Isolation of a gammaherpesvirus similar to asinine herpesvirus-2 (AHV-2) from a mule and a survey of mules and donkeys for AHV-2 infection by real-time PCR.

PubMed

Bell, Stephanie A; Pusterla, Nicola; Balasuriya, Udeni B R; Mapes, Samantha M; Nyberg, Nicole L; MacLachlan, N James

2008-07-27

Equids are commonly infected by herpesviruses, but isolation of herpesviruses from mules has apparently not been previously reported. Furthermore, the genomic relationships among the various equid herpesviruses are poorly characterized. We describe the isolation and preliminary characterization of a mule gammaherpesvirus tentatively identified as asinine herpesvirus-2 (AHV-2; also designated equid herpesvirus-7 (EHV-7)) from the nasal secretions (NS) of a healthy mule in northern California. The virus was initially identified by transmission electron microscopic examination of lysates of cell culture inoculated with NS collected from the mule. A 913 nucleotide sequence of the DNA polymerase gene was amplified using degenerate primers, and comparison of this sequence with those of various other herpesviruses showed that the mule herpesvirus was most closely related to EHV-2 (AHV-2 sequences were not available for comparison). The sequence of a shorter portion (166 nucleotides) of the mule herpesvirus DNA polymerase gene was identical to that of the published sequence of an asinine gammaherpesvirus, previously designated as AHV-4-3 (AY054992). AHV-2 was detected by real-time polymerase chain reaction assay in the NS of approximately 8% of a cohort of 114 healthy mules and 13 donkeys.

The new Mobile Universal Lexicon Evaluation System (MULES): A test of rapid picture naming for concussion sized for the sidelines.

PubMed

Akhand, Omar; Galetta, Matthew S; Cobbs, Lucy; Hasanaj, Lisena; Webb, Nikki; Drattell, Julia; Amorapanth, Prin; Rizzo, John-Ross; Nolan, Rachel; Serrano, Liliana; Rucker, Janet C; Cardone, Dennis; Jordan, Barry D; Silverio, Arlene; Galetta, Steven L; Balcer, Laura J

2018-04-15

Measures of rapid automatized naming (RAN) have been used for over 50 years to capture vision-based aspects of cognition. The Mobile Universal Lexicon Evaluation System (MULES) is a test of rapid picture naming under investigation for detection of concussion and other neurological disorders. MULES was designed as a series of 54 grouped color photographs (fruits, random objects, animals) that integrates saccades, color perception and contextual object identification. Recent changes to the MULES test have been made to improve ease of use on the athletic sidelines. Originally an 11 × 17-inch single-sided paper, the test has been reduced to a laminated 8.5 × 11-inch double-sided version. We identified performance changes associated with transition to the new, MULES, now sized for the sidelines, and examined MULES on the sideline for sports-related concussion. We administered the new laminated MULES to a group of adult office volunteers as well as youth and collegiate athletes during pre-season baseline testing. Athletes with concussion underwent sideline testing after injury. Time scores for the new laminated MULES were compared to those for the larger version (big MULES). Among 501 athletes and office volunteers (age 16 ± 7 years, range 6-59, 29% female), average test times at baseline were 44.4 ± 14.4 s for the new laminated MULES (n = 196) and 46.5 ± 16.3 s for big MULES (n = 248). Both versions were completed by 57 participants, with excellent agreement (p < 0.001, linear regression, accounting for age). Age was a predictor of test times for both MULES versions, with longer times noted for younger participants (p < 0.001). Among 6 athletes with concussion thus far during the fall sports season (median age 15 years, range 11-21) all showed worsening of MULES scores from pre-season baseline (median 4.0 s, range 2.1-16.4). The MULES test has been converted to an 11 × 8.5-inch laminated version, with excellent agreement between versions across age groups. Feasibly administered at pre-season and in an office setting, the MULES test shows preliminary evidence of capacity to identify athletes with sports-related concussion. Copyright © 2018 Elsevier B.V. All rights reserved.

Mule deer and pronghorn migration in western Wyoming

USGS Publications Warehouse

Sawyer, H.; Lindzey, F.; McWhirter, D.

2005-01-01

Migratory mule deer (Odocoileus hemionus) and pronghorn (Antilocapra americana) populations rely on seasonal ranges to meet their annual nutritional and energetic requirements. Because seasonal ranges often occur great distances apart and across a mix of vegetation types and land ownership, maintaining migration corridors to and from these ranges can be difficult, especially if managers do not have detailed information on mule deer and pronghorn seasonal movements. We captured, radiomarked, and monitored mule deer (n = 171) and pronghorn (n = 34) in western Wyoming to document seasonal distribution patterns and migration routes. Mule deer and pronghorn migrated 20-158 km and 116-258 km, respectively, between seasonal ranges. These distances represented the longest recorded migrations for either species. We identified a number of bottlenecks along the migration routes of mule deer and pronghorn, but the most critical appeared to be the 1.6-km-wide Trapper's Point bottleneck, which was used by both mule deer and pronghorn during their spring and autumn migrations. Housing developments and roadways apparently have reduced the effective width of this bottleneck to <0.8 km. We estimate 2,500-3,500 mule deer and 1,500-2,000 pronghorn move through the bottleneck twice a year during spring and autumn migrations. Identification and protection of migration corridors and bottlenecks will be necessary to maintain mule deer and pronghorn populations throughout their range.

Post-1900 mule deer irruptions in the Intermountain West: Principal cause and influences

Treesearch

George E. Gruell

1986-01-01

Tests hypotheses for mule deer population increases between the early 1930's and mid-1960's. Concludes that livestock grazing and absence of fire converted vast areas of grasses and forbs to woody plants favored by mule deer. Mule deer populations, therefore, irrupted between 1930 and 1965 and have since experienced a decline as plant succession moves toward...

Summer trapping method for mule deer. [Nevada Test Site

DOE Office of Scientific and Technical Information (OSTI.GOV)

Giles, K.R.

1979-07-01

A summer mule deer trapping method which uses modified Clover traps in a circular corral with water as a bait is described. Drug restraint was used to facilitate safe handling of mule deer by the investigator. Fifteen mule deer were safely captured and outfitted with radio transmitters, ear tags, and reflective markers, and their movements monitored to determine migration patterns.

Does small-perimeter fencing inhibit mule deer or pronghorn use of water developments?

USGS Publications Warehouse

Larsen, R.T.; Bissonette, J.A.; Flinders, J.T.; Robinson, A.C.

2011-01-01

Wildlife water development can be an important habitat management strategy in western North America for many species, including both pronghorn (Antilocapra americana) and mule deer (Odocoileus hemionus). In many areas, water developments are fenced (often with small-perimeter fencing) to exclude domestic livestock and feral horses. Small-perimeter exclosures could limit wild ungulate use of fenced water sources, as exclosures present a barrier pronghorn and mule deer must negotiate to gain access to fenced drinking water. To evaluate the hypothesis that exclosures limit wild ungulate access to water sources, we compared use (photo counts) of fenced versus unfenced water sources for both pronghorn and mule deer between June and October 2002-2008 in western Utah. We used model selection to identify an adequate distribution and best approximating model. We selected a zero-inflated negative binomial distribution for both pronghorn and mule deer photo counts. Both pronghorn and mule deer photo counts were positively associated with sampling time and average daily maximum temperature in top models. A fence effect was present in top models for both pronghorn and mule deer, but mule deer response to small-perimeter fencing was much more pronounced than pronghorn response. For mule deer, we estimated that presence of a fence around water developments reduced photo counts by a factor of 0.25. We suggest eliminating fencing of water developments whenever possible or fencing a big enough area around water sources to avoid inhibiting mule deer. More generally, our results provide additional evidence that water development design and placement influence wildlife use. Failure to account for species-specific preferences will limit effectiveness of management actions and could compromise research results. Copyright ?? 2011 The Wildlife Society.

Influence of precipitation and crop germination on resource selection by mule deer (Odocoileus hemionus) in southwest Colorado

USGS Publications Warehouse

Carrollo, Emily M.; Johnson, Heather E.; Fischer, Justin W.; Hammond, Matthew; Dorsey, Patricia D.; Anderson, Charles; Vercauteren, Kurt C.; Walter, W. David

2017-01-01

Mule deer (Odocoileus hemionus) populations in the western United States provide many benefits to local economies but can also cause considerable damage to agriculture, particularly damage to lucrative crops. Limited information exists to understand resource selection of mule deer in response to annual variation in crop rotation and climatic conditions. We tested the hypothesis that mule deer select certain crops, and in particular sunflower, based on annual climatic variability. Our objective was to use movements, estimates of home range, and resource selection analysis to identify resources selected by mule deer. We used annually-derived crop-specific datasets along with Global Positioning System collars to monitor 14 mule deer in an agricultural area near public lands in southwestern Colorado, USA. We estimated home ranges for two winter seasons that ranged between 7.68 and 9.88 km2, and for two summer seasons that ranged between 5.51 and 6.24 km2. Mule deer selected areas closer to forest and alfalfa for most periods during 2012, but selected areas closer to sunflower in a majority of periods during 2013. Considerable annual variation in climate patterns and precipitation levels appeared to influence selection by mule deer because of variability in crop rotation and success of germination of specific crops.

Summer Watering Patterns of Mule Deer in the Great Basin Desert, USA: Implications of Differential Use by Individuals and the Sexes for Management of Water Resources

PubMed Central

Shields, Andrew V.; Larsen, Randy T.; Whiting, Jericho C.

2012-01-01

Changes in the abundance and distribution of free water can negatively influence wildlife in arid regions. Free water is considered a limiting factor for mule deer (Odocoileus hemionus) in the Great Basin Desert. Consequently, a better understanding of differential use of water by individuals and the sexes could influence the conservation and management of mule deer and water resources in their habitats. We deployed remote cameras at all known water sources (13 wildlife water developments and 4 springs) on one mountain range in western Utah, USA, during summer from 2007 to 2011 to document frequency and timing of water use, number of water sources used by males and females, and to estimate population size from individually identified mule deer. Male and female mule deer used different water sources but visited that resource at similar frequencies. Individual mule deer used few water sources and exhibited high fidelity to that resource. Wildlife water developments were frequently used by both sexes. Our results highlight the differing use of water sources by sexes and individual mule deer. This information will help guide managers when siting and reprovisioning wildlife water developments meant to benefit mule deer and will contribute to the conservation and management of this species. PMID:23125557

Influence of Precipitation and Crop Germination on Resource Selection by Mule Deer (Odocoileus hemionus) in Southwest Colorado.

PubMed

Carrollo, Emily M; Johnson, Heather E; Fischer, Justin W; Hammond, Matthew; Dorsey, Patricia D; Anderson, Charles; Vercauteren, Kurt C; Walter, W David

2017-11-09

Mule deer (Odocoileus hemionus) populations in the western United States provide many benefits to local economies but can also cause considerable damage to agriculture, particularly damage to lucrative crops. Limited information exists to understand resource selection of mule deer in response to annual variation in crop rotation and climatic conditions. We tested the hypothesis that mule deer select certain crops, and in particular sunflower, based on annual climatic variability. Our objective was to use movements, estimates of home range, and resource selection analysis to identify resources selected by mule deer. We used annually-derived crop-specific datasets along with Global Positioning System collars to monitor 14 mule deer in an agricultural area near public lands in southwestern Colorado, USA. We estimated home ranges for two winter seasons that ranged between 7.68 and 9.88 km 2 , and for two summer seasons that ranged between 5.51 and 6.24 km 2 . Mule deer selected areas closer to forest and alfalfa for most periods during 2012, but selected areas closer to sunflower in a majority of periods during 2013. Considerable annual variation in climate patterns and precipitation levels appeared to influence selection by mule deer because of variability in crop rotation and success of germination of specific crops.

Summer watering patterns of mule deer in the Great Basin Desert, USA: implications of differential use by individuals and the sexes for management of water resources.

PubMed

Shields, Andrew V; Larsen, Randy T; Whiting, Jericho C

2012-01-01

Changes in the abundance and distribution of free water can negatively influence wildlife in arid regions. Free water is considered a limiting factor for mule deer (Odocoileus hemionus) in the Great Basin Desert. Consequently, a better understanding of differential use of water by individuals and the sexes could influence the conservation and management of mule deer and water resources in their habitats. We deployed remote cameras at all known water sources (13 wildlife water developments and 4 springs) on one mountain range in western Utah, USA, during summer from 2007 to 2011 to document frequency and timing of water use, number of water sources used by males and females, and to estimate population size from individually identified mule deer. Male and female mule deer used different water sources but visited that resource at similar frequencies. Individual mule deer used few water sources and exhibited high fidelity to that resource. Wildlife water developments were frequently used by both sexes. Our results highlight the differing use of water sources by sexes and individual mule deer. This information will help guide managers when siting and reprovisioning wildlife water developments meant to benefit mule deer and will contribute to the conservation and management of this species.

Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2

PubMed Central

Zhang, Jing; Kan, Shu; Huang, Brian; Hao, Zhenyue; Mak, Tak W.; Zhong, Qing

2011-01-01

Histone deacetylases (HDACs) are major epigenetic modulators involved in a broad spectrum of human diseases including cancers. Administration of HDAC inhibitors (HDACis) leads to growth inhibition, differentiation, and apoptosis of cancer cells. Understanding the regulatory mechanism of HDACs is imperative to harness the therapeutic potentials of HDACis. Here we show that HDACi- and DNA damage-induced apoptosis are severely compromised in mouse embryonic fibroblasts lacking a HECT domain ubiquitin ligase, Mule (Mcl-1 ubiquitin ligase E3). Mule specifically targets HDAC2 for ubiquitination and degradation. Accumulation of HDAC2 in Mule-deficient cells leads to compromised p53 acetylation as well as crippled p53 transcriptional activation, accumulation, and apoptotic response upon DNA damage and Nutlin-3 treatments. These defects in Mule-null cells can be partially reversed by HDACis and fully rescued by lowering the elevated HDAC2 in Mule-null cells to the normal levels as in wild-type cells. Taken together, our results reveal a critical regulatory mechanism of HDAC2 by Mule and suggest this pathway determines the cellular response to HDACis and DNA damage. PMID:22016339

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression.

PubMed

Hao, Zhenyue; Sheng, Yi; Duncan, Gordon S; Li, Wanda Y; Dominguez, Carmen; Sylvester, Jennifer; Su, Yu-Wen; Lin, Gloria H Y; Snow, Bryan E; Brenner, Dirk; You-Ten, Annick; Haight, Jillian; Inoue, Satoshi; Wakeham, Andrew; Elford, Alisha; Hamilton, Sara; Liang, Yi; Zúñiga-Pflücker, Juan C; He, Housheng Hansen; Ohashi, Pamela S; Mak, Tak W

2017-01-13

T-cell proliferation is regulated by ubiquitination but the underlying molecular mechanism remains obscure. Here we report that Lys-48-linked ubiquitination of the transcription factor KLF4 mediated by the E3 ligase Mule promotes T-cell entry into S phase. Mule is elevated in T cells upon TCR engagement, and Mule deficiency in T cells blocks proliferation because KLF4 accumulates and drives upregulation of its transcriptional targets E2F2 and the cyclin-dependent kinase inhibitors p21 and p27. T-cell-specific Mule knockout (TMKO) mice develop exacerbated experimental autoimmune encephalomyelitis (EAE), show impaired generation of antigen-specific CD8 + T cells with reduced cytokine production, and fail to clear LCMV infections. Thus, Mule-mediated ubiquitination of the novel substrate KLF4 regulates T-cell proliferation, autoimmunity and antiviral immune responses in vivo.

KSC-08pd2294

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – The shipping container with the Multi-Use Lightweight Equipment (MULE) carrier inside comes to rest in the airlock in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The cover will be removed in the airlock. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

SeqMule: automated pipeline for analysis of human exome/genome sequencing data.

PubMed

Guo, Yunfei; Ding, Xiaolei; Shen, Yufeng; Lyon, Gholson J; Wang, Kai

2015-09-18

Next-generation sequencing (NGS) technology has greatly helped us identify disease-contributory variants for Mendelian diseases. However, users are often faced with issues such as software compatibility, complicated configuration, and no access to high-performance computing facility. Discrepancies exist among aligners and variant callers. We developed a computational pipeline, SeqMule, to perform automated variant calling from NGS data on human genomes and exomes. SeqMule integrates computational-cluster-free parallelization capability built on top of the variant callers, and facilitates normalization/intersection of variant calls to generate consensus set with high confidence. SeqMule integrates 5 alignment tools, 5 variant calling algorithms and accepts various combinations all by one-line command, therefore allowing highly flexible yet fully automated variant calling. In a modern machine (2 Intel Xeon X5650 CPUs, 48 GB memory), when fast turn-around is needed, SeqMule generates annotated VCF files in a day from a 30X whole-genome sequencing data set; when more accurate calling is needed, SeqMule generates consensus call set that improves over single callers, as measured by both Mendelian error rate and consistency. SeqMule supports Sun Grid Engine for parallel processing, offers turn-key solution for deployment on Amazon Web Services, allows quality check, Mendelian error check, consistency evaluation, HTML-based reports. SeqMule is available at http://seqmule.openbioinformatics.org.

Mule determines the apoptotic response to HDAC inhibitors by targeted ubiquitination and destruction of HDAC2.

PubMed

Zhang, Jing; Kan, Shu; Huang, Brian; Hao, Zhenyue; Mak, Tak W; Zhong, Qing

2011-12-15

Histone deacetylases (HDACs) are major epigenetic modulators involved in a broad spectrum of human diseases including cancers. Administration of HDAC inhibitors (HDACis) leads to growth inhibition, differentiation, and apoptosis of cancer cells. Understanding the regulatory mechanism of HDACs is imperative to harness the therapeutic potentials of HDACis. Here we show that HDACi- and DNA damage-induced apoptosis are severely compromised in mouse embryonic fibroblasts lacking a HECT domain ubiquitin ligase, Mule (Mcl-1 ubiquitin ligase E3). Mule specifically targets HDAC2 for ubiquitination and degradation. Accumulation of HDAC2 in Mule-deficient cells leads to compromised p53 acetylation as well as crippled p53 transcriptional activation, accumulation, and apoptotic response upon DNA damage and Nutlin-3 treatments. These defects in Mule-null cells can be partially reversed by HDACis and fully rescued by lowering the elevated HDAC2 in Mule-null cells to the normal levels as in wild-type cells. Taken together, our results reveal a critical regulatory mechanism of HDAC2 by Mule and suggest this pathway determines the cellular response to HDACis and DNA damage. © 2011 by Cold Spring Harbor Laboratory Press

Polonium assimilation and retention in mule deer and pronghorn antelope

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sejkora, K.J.

Excretion kinetics and tissue distribution of polonium-210 in mule deer and pronghorn were studied. Each animal in a captive herd of 7 mule deer and 2 pronghorn received an intraruminal injection of 4.4 ..mu..Ci of polonium chloride. Feces and urine were collected periodically over a 43-day period and daily excretion rate for each pathway was regressed as a function of time. Assimilation fractions of 0.40 and 0.51 were calculated for mule deer (n=2) and 0.60 for a pronghorn. Body burden retention functions were calculated from integrated excretion rate functions. Polonium burdens in muscle, liver, and kidney were calculated as amore » fraction of body burden from serially-sacrificed animals. Background tissue burdens in mule deer were comparable to those of other ruminants reported in the literature. Hypothetical cases were assumed which combined feeding rate of mule deer, forage concentrations of polonium, retention function, tissue burden fraction, and human intake to estimate human radiation dose. 26 references.« less

Analysis of a MULE-cyanide hydratase gene fusion in Verticillium dahliae

USDA-ARS?s Scientific Manuscript database

The genome of the phytopathogenic fungus Verticillium dahliae encodes numerous Class II “cut-and-paste” transposable elements, including those of a small group of MULE transposons. We have previously identified a fusion event between a MULE transposon sequence and sequence encoding a cyanide hydrata...

Mule Regulates the Intestinal Stem Cell Niche via the Wnt Pathway and Targets EphB3 for Proteasomal and Lysosomal Degradation.

PubMed

Dominguez-Brauer, Carmen; Hao, Zhenyue; Elia, Andrew J; Fortin, Jérôme M; Nechanitzky, Robert; Brauer, Patrick M; Sheng, Yi; Mana, Miyeko D; Chio, Iok In Christine; Haight, Jillian; Pollett, Aaron; Cairns, Robert; Tworzyanski, Leanne; Inoue, Satoshi; Reardon, Colin; Marques, Ana; Silvester, Jennifer; Cox, Maureen A; Wakeham, Andrew; Yilmaz, Omer H; Sabatini, David M; van Es, Johan H; Clevers, Hans; Sato, Toshiro; Mak, Tak W

2016-08-04

The E3 ubiquitin ligase Mule is often overexpressed in human colorectal cancers, but its role in gut tumorigenesis is unknown. Here, we show in vivo that Mule controls murine intestinal stem and progenitor cell proliferation by modulating Wnt signaling via c-Myc. Mule also regulates protein levels of the receptor tyrosine kinase EphB3 by targeting it for proteasomal and lysosomal degradation. In the intestine, EphB/ephrinB interactions position cells along the crypt-villus axis and compartmentalize incipient colorectal tumors. Our study thus unveils an important new avenue by which Mule acts as an intestinal tumor suppressor by regulation of the intestinal stem cell niche. Copyright © 2016 Elsevier Inc. All rights reserved.

Short beak and dwarfism syndrome of mule duck is caused by a distinct lineage of goose parvovirus.

PubMed

Palya, Vilmos; Zolnai, Anna; Benyeda, Zsófia; Kovács, Edit; Kardi, Veronika; Mató, Tamás

2009-04-01

From the early 1970s to the present, numerous cases of short beak and dwarfism syndrome (SBDS) have been reported in mule ducks from France. The animals showed strong growth retardation with smaller beak and tarsus. It was suggested that the syndrome was caused by goose parvovirus on the basis of serological investigation, but the causative agent has not been isolated and the disease has not so far been reproduced by experimental infection. The aim of the present study was to characterize the virus strains isolated from field cases of SBDS, and to reproduce the disease experimentally. Phylogenetic analysis proved that the parvovirus isolates obtained from SBDS of mule duck belonged to a distinct lineage of goose parvovirus-related group of waterfowl parvoviruses. The authors carried out experimental infections of 1-day-old, 2-week-old and 3-week-old mule ducks by the oral route with three different parvovirus strains: strain D17/99 of goose parvovirus from Derzsy's disease, strain FM of Muscovy duck parvovirus from the parvovirus disease of Muscovy ducks, and strain D176/02 isolated from SBDS of mule duck. The symptoms of SBDS of the mule duck could only be reproduced with the mule duck isolate (strain D176/02) following 1-day-old inoculation. Infection with a genetically different strain of goose parvovirus isolated from classical Derzsy's disease (D17/99) or with the Muscovy duck parvovirus strain (FM) did not cause any clinical symptoms or pathological lesions in mule ducks.

Estimation of survival rates from band recoveries of mule deer in Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G.C.; Bartmann, R.M.

1983-01-01

An attempt has been made to determine the survival rate of mule deer in the White River drainage basin in northwestern Colorado. During five winters, 1972-76, 1923 mule deer were trapped and marked. Survival rates were determined at yearly intervals. A FORTRAN program was used to perform the analysis.

Tolazoline-induced apnea in mule deer (Odocoileus hemionus).

PubMed

Mortenson, Jack Alan; Robison, Jason Andrew

2011-03-01

Eighteen mule deer (Odocoileus hemionus) and six Columbia black-tailed deer (Odocoileus hemionus columbianus) were held in pens and repeatedly anesthetized from April 2004 through June 2005 as part of an external parasite study. Deer were anesthetized using a combination of Telazol and xylazine hydrochloride (HCL) administered intramuscularly. Tolazoline HCL was slowly administered at 4 mg/kg intravenously to reverse the effects of xylazine with good results. For 17 of the 19 mule deer anesthesias in the fall of 2004, a mean dose of 7.3 mg/kg of intravenous tolazoline (range 6.1-8.4 mg/kg) was given by mistake. This paper describes clinical signs of apnea, muscle tensing, and fasciculations immediately following intravenous administration of tolazoline HCL in mule deer (O. hemionus) at 1.5-3 times the recommended dose. Mean dose for black-tailed deer during this time was 8.1 mg/kg (range 5.5-12.4 mg/kg) with no clinical signs as seen in the mule deer. Based on these findings, intravenous tolazoline use in mule deer is recommended at < or = 4 mg/kg.

Microsatellites indicate minimal barriers to mule deer Odocoileus hemionus dispersal across Montana, USA

USGS Publications Warehouse

Powell, John H.; Kalinowski, Steven T.; Higgs, Megan D.; Ebinger, Michael R.; Vu, Ninh V.; Cross, Paul C.

2013-01-01

To better understand the future spread of chronic wasting disease, we conducted a genetic assessment of mule deer Odocoileus hemionus population structure across the state of Montana, USA. Individual based analyses were used to test for population structure in the absence of a priori designations of population membership across the sampling area. Samples from the states of Wyoming, Colorado and Utah were also included in the analysis to provide a geographic context to the levels of population structure observed within Montana. Results showed that mule deer across our entire study region were characterized by weak isolation by distance and a lack of spatial autocorrelation at distances > 10 km. We found evidence for contemporary male bias in dispersal, with female mule deer exhibiting higher mean individual pairwise genetic distance than males. We tested for potential homogenizing effects of past translocations within Montana, but were unable to detect a genetic signature of these events. Our results indicate high levels of connectivity among mule deer populations in Montana and suggest few, if any, detectable barriers to mule deer gene flow or chronic wasting disease transmission.

Mule deer and energy development-Long-term trends of habituation and abundance.

PubMed

Sawyer, Hall; Korfanta, Nicole M; Nielson, Ryan M; Monteith, Kevin L; Strickland, Dale

2017-11-01

As the extent and intensity of energy development in North America increases, so do disturbances to wildlife and the habitats they rely upon. Impacts to mule deer are of particular concern because some of the largest gas fields in the USA overlap critical winter ranges. Short-term studies of 2-3 years have shown that mule deer and other ungulates avoid energy infrastructure; however, there remains a common perception that ungulates habituate to energy development, and thus, the potential for a demographic effect is low. We used telemetry data from 187 individual deer across a 17-year period, including 2 years predevelopment and 15 years during development, to determine whether mule deer habituated to natural gas development and if their response to disturbance varied with winter severity. Concurrently, we measured abundance of mule deer to indirectly link behavior with demography. Mule deer consistently avoided energy infrastructure through the 15-year period of development and used habitats that were an average of 913 m further from well pads compared with predevelopment patterns of habitat use. Even during the last 3 years of study, when most wells were in production and reclamation efforts underway, mule deer remained >1 km away from well pads. The magnitude of avoidance behavior, however, was mediated by winter severity, where aversion to well pads decreased as winter severity increased. Mule deer abundance declined by 36% during the development period, despite aggressive onsite mitigation efforts (e.g. directional drilling and liquid gathering systems) and a 45% reduction in deer harvest. Our results indicate behavioral effects of energy development on mule deer are long term and may affect population abundance by displacing animals and thereby functionally reducing the amount of available habitat. © 2017 The Authors. Global Change Biology Published by John Wiley & Sons Ltd.

Genetic population structure and relatedness of Colorado mule deer (Odocoileus hemionus) and incidence of chronic wasting disease

USDA-ARS?s Scientific Manuscript database

Chronic wasting disease is a transmissible spongiform encephalopathy or prion disease of farmed and free ranging mule deer, white tailed deer, Rocky Mountain elk, and moose in some areas of the United States. The disease is enzootic in herds of free ranging mule deer in the Rocky Mountain National ...

Wildlife habitats in managed rangelands—the Great Basin of southeastern Oregon: mule deer.

Treesearch

Donavin A. Leckenby; Dennis P. Sheehy; Carl H. Nellis; Richard J. Scherzinger; Ira D. Luman; Wayne Elmore; James C. Lemos; Larry Doughty; Charles E. Trainer

1982-01-01

Relationships of mule deer behavior and physiology to management of shrub steppe plant communities in the Great Basin of southeastern Oregon are presented for application in land-use planning and habitat management. Communities are considered as they are used by mule deer for thermal cover, hiding cover, forage, fawning, and fawn rearing.

Evaluation of vaginal implants for mule deer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garrott, R.A.; Bartmann, R.M.

1984-01-01

It is difficult to obtain information on the biology of the mule deer (Odocoileus hemionus) during the first several months of life because of the seclusive nature of fawns. Radio-transmitter implants were placed in the vaginas of mule deer to facilitate determining the time and location of parturition and to evaluate the effects on dams in the Piceance Basin, northwest Colorado.

Soil disturbances from horse/mule logging operations coupled with machines in the Southern United States

Treesearch

Suraj P. Shrestha; Bobby L. Lanford; Robert Rummer; Mark Dubois

2008-01-01

Forest harvesting with animals is a labor-intensive operation. While mechanized logging is very efficient for large tracts of timber, it is often disruptive to the soil. Small logging operations using animals may be less environmentally disruptive. To better understand horse/mule logging performances for soil disturbance, five different horse/mule harvesting operations...

Chemical immobilization of North American mule deer

USGS Publications Warehouse

Lange, Robert E.; Nielsen, Leon; Haigh, Jerry C.; Fowler, Murray E.

1983-01-01

The choice of agents for chemical immobilization of mule deer (Odocoileus hemionus) is a problem with a simple and effective solution, in my opinion. I recommend combinations of etorphine hydrochloride (M199©) and xylazine hydrochloride (Rompun©) administered intravenously and reversed intravenously. I have used this combination on hundreds of mule deer and have supervised its use on hundreds more. It is a forgiving combination in terms of safety to the deer. I have never seen a mortality in mule deer that I could blame on this combination of drugs, which, in my experience, has performed well under a wide variety of environmental, physiological and organizational conditions.

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling.

PubMed

Dominguez-Brauer, Carmen; Khatun, Rahima; Elia, Andrew J; Thu, Kelsie L; Ramachandran, Parameswaran; Baniasadi, Shakiba P; Hao, Zhenyue; Jones, Lisa D; Haight, Jillian; Sheng, Yi; Mak, Tak W

2017-02-14

Wnt signaling, named after the secreted proteins that bind to cell surface receptors to activate the pathway, plays critical roles both in embryonic development and the maintenance of homeostasis in many adult tissues. Two particularly important cellular programs orchestrated by Wnt signaling are proliferation and stem cell self-renewal. Constitutive activation of the Wnt pathway resulting from mutation or improper modulation of pathway components contributes to cancer development in various tissues. Colon cancers frequently bear inactivating mutations of the adenomatous polyposis coli ( APC ) gene, whose product is an important component of the destruction complex that regulates β-catenin levels. Stabilization and nuclear localization of β-catenin result in the expression of a panel of Wnt target genes. We previously showed that Mule/Huwe1/Arf-BP1 (Mule) controls murine intestinal stem and progenitor cell proliferation by modulating the Wnt pathway via c-Myc. Here we extend our investigation of Mule's influence on oncogenesis by showing that Mule interacts directly with β-catenin and targets it for degradation under conditions of hyperactive Wnt signaling. Our findings suggest that Mule uses various mechanisms to fine-tune the Wnt pathway and provides multiple safeguards against tumorigenesis.

Failure of fallow deer (Dama dama) to develop chronic wasting disease when exposed to a contaminated environment and infected mule deer (Odocoileus hemionus).

PubMed

Rhyan, Jack C; Miller, Michael W; Spraker, Terry R; McCollum, Matt; Nol, Pauline; Wolfe, Lisa L; Davis, Tracy R; Creekmore, Lynn; O'Rourke, Katherine I

2011-07-01

We monitored a herd of fallow deer (Dama dama) for evidence of prion infection for 7 yr by periodic postmortem examination of animals from the herd. The fallow deer were exposed to the chronic wasting disease (CWD) agent from mule deer by living in a paddock considered contaminated with infectivity from its history of housing CWD infected deer and, after the first year of the study, by comingling with infected mule deer (Odocoileus hemionus). At least 8 of 12 mule deer serving as sentinels for prion transmission and 25 additional mule deer serving as sources of infectivity developed clinical CWD or were otherwise confirmed to be infected with CWD via lymphoid tissue immunohistochemistry (IHC). In contrast, none of the 41 exposed fallow deer showed clinical signs suggestive of CWD, IHC staining of disease-associated prion in lymphoid or brain tissues, or evidence of spongiform degeneration in sections of brain stem at the level of the obex when sampled 18 mo to 7 yr after entering the mule deer paddock. The absence of clinical disease and negative IHC results in fallow deer housed in the same contaminated paddock for up to 7 yr and almost continuously exposed to CWD-infected mule deer for up to 6 yr suggests a species barrier or other form of resistance preventing fallow deer infection by the CWD agent or delaying progression of the disease in this species.

A versatile modular vector system for rapid combinatorial mammalian genetics.

PubMed

Albers, Joachim; Danzer, Claudia; Rechsteiner, Markus; Lehmann, Holger; Brandt, Laura P; Hejhal, Tomas; Catalano, Antonella; Busenhart, Philipp; Gonçalves, Ana Filipa; Brandt, Simone; Bode, Peter K; Bode-Lesniewska, Beata; Wild, Peter J; Frew, Ian J

2015-04-01

Here, we describe the multiple lentiviral expression (MuLE) system that allows multiple genetic alterations to be introduced simultaneously into mammalian cells. We created a toolbox of MuLE vectors that constitute a flexible, modular system for the rapid engineering of complex polycistronic lentiviruses, allowing combinatorial gene overexpression, gene knockdown, Cre-mediated gene deletion, or CRISPR/Cas9-mediated (where CRISPR indicates clustered regularly interspaced short palindromic repeats) gene mutation, together with expression of fluorescent or enzymatic reporters for cellular assays and animal imaging. Examples of tumor engineering were used to illustrate the speed and versatility of performing combinatorial genetics using the MuLE system. By transducing cultured primary mouse cells with single MuLE lentiviruses, we engineered tumors containing up to 5 different genetic alterations, identified genetic dependencies of molecularly defined tumors, conducted genetic interaction screens, and induced the simultaneous CRISPR/Cas9-mediated knockout of 3 tumor-suppressor genes. Intramuscular injection of MuLE viruses expressing oncogenic H-RasG12V together with combinations of knockdowns of the tumor suppressors cyclin-dependent kinase inhibitor 2A (Cdkn2a), transformation-related protein 53 (Trp53), and phosphatase and tensin homolog (Pten) allowed the generation of 3 murine sarcoma models, demonstrating that genetically defined autochthonous tumors can be rapidly generated and quantitatively monitored via direct injection of polycistronic MuLE lentiviruses into mouse tissues. Together, our results demonstrate that the MuLE system provides genetic power for the systematic investigation of the molecular mechanisms that underlie human diseases.

Mule cognition: a case of hybrid vigour?

PubMed

Proops, Leanne; Burden, Faith; Osthaus, Britta

2009-01-01

This study compares the behaviour of the mule (Equus asinus x Equus caballus) with that of its parent species to assess the effects of hybridization on cognition. Six mules, six ponies (E. caballus) and six donkeys (E. asinus) were given a two choice visual discrimination learning task. Each session consisted of 12 trials and pass level was reached when subjects chose the correct stimulus for at least 9 out of the 12 trials in three consecutive sessions. A record was made of how many pairs each subject learnt over 25 sessions. The mules' performance was significantly better than that of either of the parent species (Kruskal-Wallis: H(x) = 8.11, P = 0.017). They were also the only group to learn enough pairs to be able to show a successive reduction in the number of sessions required to reach criterion level. This study provides the first empirical evidence that the improved characteristics of mules may be extended from physical attributes to cognitive function.

Age and sex selectivity in trapping mule deer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Garrott, R.A.; White, G.C.

1982-01-01

A mule deer (Odocoileus hemionus) trapping experiment is described using modified Clover traps in which changes in the placement of bait and height of the trap door modified the ratio of adult does to male and female fawns captured. The mechanisms responsible for the changes in age-sex capture ratios are discussed and indicate that modified Clover traps selectivity capture mule deer, thus introducing bias into population sampling. (JMT)

Observations on coyote-mule deer interactions at Rocky Flats, Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alldredge, A.W.; Arthur, W.J. III

1980-01-01

Observations of interactions between coyotes (Canis latrans) and mule deer (Odocoileus hemionus) in N-central Colorado indicated that, upon discovering a coyote close to a herd, mule deer would become alert, bunch together and either flee or pursue the coyote. Two observations of coyotes attacking deer indicated that the rump was the probable point of attack and in one case the deer began a defense using its front hooves.

Mitochondrial and nuclear genetic relationships of deer (Odocoileus spp.) in western North America

USGS Publications Warehouse

Cronin, Matthew A.

1991-01-01

Odocoileus hemionus (mule deer and black-tailed deer) and Odocoileus virginanus (white-tailed deer) are sympatric in western North America and are characterized by distinct morphology, behavior, and allozyme allele frequencies. However, there is discordance among nuclear and mitochondrial genetic relationships, as mule deer (O. h. hemionus) and white-tailed deer have similar mitochondrial DNA (mtDNA) which is very different from that of black-tailed deer (O. h. columbianus, O. h. sitkensis). I expanded previous studies to clarify the genetic relationships of these groups by determining mtDNA haplotype and allozyme genotypes for 667 deer from several locations in northwestern North America. Different mtDNA haplotypes in mule deer, black-tailed deer, and white-tailed deer indicate that mitochondrial gene flow is restricted. Allozyme allele frequencies indicate that there is also restriction of nuclear gene flow between O. virginianus and O. hemionus, and to a lesser extent between mule deer and black-tailed deer. There is a low level of introgressive hybridization of mtDNA from mule deer and black-tailed deer into white-tailed deer populations and considerable interbreeding of mule deer and black-tailed deer in a contact zone. The discordance of mitochondrial and nuclear genomes is apparent only if mtDNA sequence divergences, and not haplotype frequencies, are considered.

Using Pop-II models to predict effects of wolf predation and hunter harvests on elk, mule deer, and moose on the northern range

USGS Publications Warehouse

Mack, John A.; Singer, Francis J.

1993-01-01

The effects of establishing a gray wolf (Canis lupus) population in Yellowstone National Park were predicted for three ungulate species—elk (Cervus elaphus), mule deer (Odocoileus hemionus), and moose (Alces alces)—using previously developed POP-II population models. We developed models for 78 and 100 wolves. For each wolf population, we ran scenarios using wolf predation rates of 9, 12, and 15 ungulates/wolf/year. With 78 wolves and the antlerless elk harvest reduced 27%, our modeled elk population estimated were 5-18% smaller than the model estimate without wolves. With 100 wolves and the antlerless elk harvest reduced 27%, our elk population estimated were 11-30% smaller than the population estimates without wolves. Wolf predation effects were greater on the modeled mule deer population than on elk. With 78 wolves and no antlerless deer harvest, we predicted the mule deer population could be 13-44% larger than without wolves. With 100 wolves and no antlerless deer harvest, the mule deer population was 0-36% larger than without wolves. After wolf recovery, our POP-II models suggested moose harvests would have to be reduced at least 50% to maintain moose numbers at the levels predicted when wolves were not present. Mule deer and moose population data are limited, and these wolf predation effects may be overestimated if population sizes or male-female ratios were underestimated in our population models. We recommend additional mule deer and moose population data be obtained.

Candidate adaptive genes associated with lineage divergence: identifying SNPs via next-generation targeted resequencing in mule deer (Odocoileus hemionus).

PubMed

Powell, John H; Amish, Stephen J; Haynes, Gwilym D; Luikart, Gordon; Latch, Emily K

2016-09-01

Mule deer (Odocoileus hemionus) are an excellent nonmodel species for empirically testing hypotheses in landscape and population genomics due to their large population sizes (low genetic drift), relatively continuous distribution, diversity of occupied habitats and phenotypic variation. Because few genomic resources are currently available for this species, we used exon data from a cattle (Bos taurus) reference genome to direct targeted resequencing of 5935 genes in mule deer. We sequenced approximately 3.75 Mbp at minimum 20X coverage in each of the seven mule deer, identifying 23 204 single nucleotide polymorphisms (SNPs) within, or adjacent to, 6886 exons in 3559 genes. We found 91 SNP loci (from 69 genes) with putatively fixed allele frequency differences between the two major lineages of mule deer (mule deer and black-tailed deer), and our estimate of mean genetic divergence (genome-wide FST  = 0.123) between these lineages was consistent with previous findings using microsatellite loci. We detected an over-representation of gamete generation and amino acid transport genes among the genes with SNPs exhibiting potentially fixed allele frequency differences between lineages. This targeted resequencing approach using exon capture techniques has identified a suite of loci that can be used in future research to investigate the genomic basis of adaptation and differentiation between black-tailed deer and mule deer. This study also highlights techniques (and an exon capture array) that will facilitate population genomic research in other cervids and nonmodel organisms. © 2016 John Wiley & Sons Ltd.

9 CFR 93.300 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

.... Animals. Cattle, sheep, goats, other ruminants, swine, horses, asses, mules, zebras, dogs, and poultry..., the varieties Americana and Australia. Horses. Horses, asses, mules, and zebras. Immediate slaughter...

9 CFR 93.300 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

.... Animals. Cattle, sheep, goats, other ruminants, swine, horses, asses, mules, zebras, dogs, and poultry..., the varieties Americana and Australia. Horses. Horses, asses, mules, and zebras. Immediate slaughter...

9 CFR 93.300 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

.... Animals. Cattle, sheep, goats, other ruminants, swine, horses, asses, mules, zebras, dogs, and poultry..., the varieties Americana and Australia. Horses. Horses, asses, mules, and zebras. Immediate slaughter...

9 CFR 93.300 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

.... Animals. Cattle, sheep, goats, other ruminants, swine, horses, asses, mules, zebras, dogs, and poultry..., the varieties Americana and Australia. Horses. Horses, asses, mules, and zebras. Immediate slaughter...

9 CFR 93.300 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

.... Animals. Cattle, sheep, goats, other ruminants, swine, horses, asses, mules, zebras, dogs, and poultry..., the varieties Americana and Australia. Horses. Horses, asses, mules, and zebras. Immediate slaughter...

The effect of terrain and female density on survival of neonatal white-tailed deer and mule deer fawns.

PubMed

Bonar, Maegwin; Manseau, Micheline; Geisheimer, Justin; Bannatyne, Travis; Lingle, Susan

2016-07-01

Juvenile survival is a highly variable life-history trait that is critical to population growth. Antipredator tactics, including an animal's use of its physical and social environment, are critical to juvenile survival. Here, we tested the hypothesis that habitat and social characteristics influence coyote (Canis latrans) predation on white-tailed deer (Odocoileus virginianus) and mule deer (O. hemionus) fawns in similar ways during the neonatal period. This would contrast to winter when the habitat and social characteristics that provide the most safety for each species differ. We monitored seven cohorts of white-tailed deer and mule deer fawns at a grassland study site in Alberta, Canada. We used logistic regression and a model selection procedure to determine how habitat characteristics, climatic conditions, and female density influenced fawn survival during the first 8 weeks of life. Fawn survival improved after springs with productive vegetation (high integrated Normalized Difference Vegetation Index values). Fawns that used steeper terrain were more likely to survive. Fawns of both species had improved survival in years with higher densities of mule deer females, but not with higher densities of white-tailed deer females, as predicted if they benefit from protection by mule deer. Our results suggest that topographical variation is a critical resource for neonates of many ungulate species, even species like white-tailed deer that use more gentle terrain when older. Further, our results raise the possibility that neonatal white-tailed fawns may benefit from associating with mule deer females, which may contribute to the expansion of white-tailed deer into areas occupied by mule deer.

Winter habitat selection of mule deer before and during development of a natural gas field

USGS Publications Warehouse

Sawyer, H.; Nielson, R.M.; Lindzey, F.; McDonald, L.L.

2006-01-01

Increased levels of natural gas exploration, development, and production across the Intermountain West have created a variety of concerns for mule deer (Odocoileus hemionus) populations, including direct habitat loss to road and well-pad construction and indirect habitat losses that may occur if deer use declines near roads or well pads. We examined winter habitat selection patterns of adult female mule deer before and during the first 3 years of development in a natural gas field in western Wyoming. We used global positioning system (GPS) locations collected from a sample of adult female mule deer to model relative frequency or probability of use as a function of habitat variables. Model coefficients and predictive maps suggested mule deer were less likely to occupy areas in close proximity to well pads than those farther away. Changes in habitat selection appeared to be immediate (i.e., year 1 of development), and no evidence of well-pad acclimation occurred through the course of the study; rather, mule deer selected areas farther from well pads as development progressed. Lower predicted probabilities of use within 2.7 to 3.7 km of well pads suggested indirect habitat losses may be substantially larger than direct habitat losses. Additionally, some areas classified as high probability of use by mule deer before gas field development changed to areas of low use following development, and others originally classified as low probability of use were used more frequently as the field developed. If areas with high probability of use before development were those preferred by the deer, observed shifts in their distribution as development progressed were toward less-preferred and presumably less-suitable habitats.

9 CFR 88.1 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... member of the Equidae family, which includes horses, asses, mules, ponies, and zebras. Equine for..., and their appurtenances, in which live cattle, sheep, swine, horses, mules, or goats are received...

9 CFR 88.1 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... member of the Equidae family, which includes horses, asses, mules, ponies, and zebras. Equine for..., and their appurtenances, in which live cattle, sheep, swine, horses, mules, or goats are received...

9 CFR 88.1 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... member of the Equidae family, which includes horses, asses, mules, ponies, and zebras. Equine for..., and their appurtenances, in which live cattle, sheep, swine, horses, mules, or goats are received...

Investigation of anatomical anomalies in Hanford Site mule deer

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tiller, B.L.; Cadwell, L.L.; Poston, T.M.

Rocky Mountain mule deer (Odocoileus hemionus hemionus), common residents of the Hanford Site, are an important part of the shrub-steppe ecosystem as well as being valued for aesthetics and hunting. Because mule deer have been protected from hunting on the Site for 50 years, the herd has developed unique population characteristics, including a large number of old animals and males with either large or atypically developed antlers, in contrast to other herds in the semi-arid regions of the Northwest. Hanford Site mule deer have been studied since 1991 because of the herd`s unique nature and high degree of public interest.more » A special study of the mule deer herd was initiated in 1993 after observations were made of a relatively large number of male deer with atypical, velvet-covered antlers. This report specifically describes our analyses of adult male deer found on the Site with atypical antlers. The report includes estimates of population densities and composition; home ranges, habitat uses, and dietary habits; natural and human-induced causes of mortality; and the herd`s overall health and reproductive status.« less

KSC-08pd2291

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – The Multi-Use Lightweight Equipment (MULE) carrier arrives at the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

Bilateral malignant seminoma with metastases in the mule: a report of two cases.

PubMed

Galofaro, V; Consiglio, C; Rapisarda, G; Marino, F

2008-02-01

We report two cases of bilateral malignant seminoma in the bursula testium of two mules, which had been slaughtered normally. Histologically, the testicular tumours consisted predominantly of large round to polyhedral cells with frequent mitotic figures. Metastases were found in the sublumbar lymph nodes. A final histopathological diagnosis of malignant seminoma with metastasis was made. To our knowledge, this paper appears to be the first report of two cases of bilateral malignant seminoma with metastases, in the mule.

Characterization of Clinically Attenuated Burkholderia mallei by Whole-Genome Sequencing: Candidate Strain for Exclusion from Select Agent Lists

DTIC Science & Technology

2008-04-01

symptoms may have been related to endotoxin . Clinical signs in the ponies and the mule were either minimal (fever) or nonexistent. All 6 equids produced ...ponies, 1 mule, 1 donkey), natural hosts, for purposes of producing antibodies. Multiple high inocula were used in some cases. Unexpectedly SAVP1 appeared...that was experimentally infected in 6 equids (4 ponies, 1 mule, 1 donkey), natural hosts, for purposes of producing antibodies. Multiple high inocula

MULE SPINNING, LOCATION UNIDENTIFIED. PHOTOCOPY OF c. 1900 VIEW. From ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

MULE SPINNING, LOCATION UNIDENTIFIED. PHOTOCOPY OF c. 1900 VIEW. From the collection of Mr. George Durette, Photographer, Manchester, N. H. - Amoskeag Millyard, Canal Street, Manchester, Hillsborough County, NH

Conserving migratory mule deer through the umbrella of sage-grouse

USGS Publications Warehouse

Copeland, H. E.; Sawyer, H.; Monteith, K. L.; Naugle, D.E.; Pocewicz, Amy; Graf, N.; Kauffman, Matthew J.

2014-01-01

Conserving migratory ungulates in increasingly human-dominated landscapes presents a difficult challenge to land managers and conservation practitioners. Nevertheless, ungulates may receive ancillary benefits from conservation actions designed to protect species of greater conservation priority where their ranges are sympatric. Greater Sage-Grouse (Centrocerus urophasianus), for example, have been proposed as an umbrella species for other sagebrush (Artemesia spp.)-dependent fauna. We examined a landscape where conservation efforts for sage-grouse overlap spatially with mule deer (Odocoileus hemionus) to determine whether sage-grouse conservation measures also might protect important mule deer migration routes and seasonal ranges. We conducted a spatial analysis to determine what proportion of migration routes, stopover areas, and winter ranges used by mule deer were located in areas managed for sage-grouse conservation. Conservation measures overlapped with 66–70% of migration corridors, 74–75% of stopovers, and 52–91% of wintering areas for two mule deer populations in the upper Green River Basin of Wyoming. Of those proportions, conservation actions targeted towards sage-grouse accounted for approximately half of the overlap in corridors and stopover areas, and nearly all overlap on winter ranges, indicating that sage-grouse conservation efforts represent an important step in conserving migratory mule deer. Conservation of migratory species presents unique challenges because although overlap with conserved lands may be high, connectivity of the entire route must be maintained as barriers to movement anywhere within the migration corridor could render it unviable. Where mule deer habitats overlap with sage-grouse core areas, our results indicate that increased protection is afforded to winter ranges and migration routes within the umbrella of sage-grouse conservation, but this protection is contingent on concentrated developments within core areas not intersecting with high-priority stopovers or corridors, and that the policy in turn does not encourage development on deer ranges outside of core areas. With the goal of protecting entire migration routes, our analysis highlights areas of potential conservation focus for mule deer, which are characterized by high exposure to residential development and use by a large proportion of migrating deer.

50 CFR 32.46 - Nebraska.

Code of Federal Regulations, 2011 CFR

2011-10-01

...-tailed deer and mule deer on designated areas of the refuge in accordance with State regulations subject... Hunting. We allow archery hunting of mule deer and white-tailed deer on designated areas of the refuge in...

36 CFR 222.50 - General procedures.

Code of Federal Regulations, 2013 CFR

2013-07-01

... adult, are equivalent to one cow, bull, steer, heifer, horse, or mule. (d) No additional charge will be... established for such use. Fees for horses, mules, or burros associated with management of permitted livestock...

9 CFR 320.1 - Records required to be kept.

Code of Federal Regulations, 2014 CFR

2014-01-01

... slaughtering any cattle, sheep, swine, goats, horses, mules, or other equines, or preparing, freezing..., horses, mules, or other equines, or parts of the carcasses of any such animals that died otherwise than...

36 CFR 222.50 - General procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

... adult, are equivalent to one cow, bull, steer, heifer, horse, or mule. (d) No additional charge will be... established for such use. Fees for horses, mules, or burros associated with management of permitted livestock...

36 CFR 222.50 - General procedures.

Code of Federal Regulations, 2012 CFR

2012-07-01

... adult, are equivalent to one cow, bull, steer, heifer, horse, or mule. (d) No additional charge will be... established for such use. Fees for horses, mules, or burros associated with management of permitted livestock...

36 CFR 222.50 - General procedures.

Code of Federal Regulations, 2014 CFR

2014-07-01

... adult, are equivalent to one cow, bull, steer, heifer, horse, or mule. (d) No additional charge will be... established for such use. Fees for horses, mules, or burros associated with management of permitted livestock...

2. VIEW OF MECHANICAL GATE LIFTING MECHANISM (MULE) AND GATE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. VIEW OF MECHANICAL GATE LIFTING MECHANISM (MULE) AND GATE LIFTING RACKS, LOOKING WEST - Nine Mile Hydroelectric Development, Powerhouse, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

36 CFR 222.50 - General procedures.

Code of Federal Regulations, 2011 CFR

2011-07-01

... adult, are equivalent to one cow, bull, steer, heifer, horse, or mule. (d) No additional charge will be... established for such use. Fees for horses, mules, or burros associated with management of permitted livestock...

3. VIEW OF MECHANICAL GATE LIFTING MECHANISM (MULE) AND GATE ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. VIEW OF MECHANICAL GATE LIFTING MECHANISM (MULE) AND GATE RACKS, LOOKING EAST - Nine Mile Hydroelectric Development, Powerhouse, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

4. DETAIL VIEW OF LIFTING GEAR ON MULE AND RACK ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. DETAIL VIEW OF LIFTING GEAR ON MULE AND RACK ATTACHMENT BOOKS, LOOKING EAST - Nine Mile Hydroelectric Development, Powerhouse, State Highway 291 along Spokane River, Nine Mile Falls, Spokane County, WA

KSC-08pd2290

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – The Multi-Use Lightweight Equipment (MULE) carrier is driven from the Canister Rotation Facility to the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center after the shipping container was pressure cleaned. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2315

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, technicians remove the protective cover from the Multi-Use Lightweight Equipment, or MULE, carrier. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2297

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the cover of the shipping container is lifted to reveal the Multi-Use Lightweight Equipment (MULE) carrier inside. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2316

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a technician removes the protective cover from the Multi-Use Lightweight Equipment, or MULE, carrier. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2312

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lowers the Multi-Use Lightweight Equipment, or MULE, carrier toward a stand in the high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2314

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, a technician begins removing the protective cover from the Multi-Use Lightweight Equipment, or MULE, carrier. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2298

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, arcane moves the cover of the shipping container away from its cargo, the Multi-Use Lightweight Equipment (MULE) carrier. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2289

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – At the Canister Rotation Facility at NASA's Kennedy Space Center, the shipping container with the Multi-Use Lightweight Equipment (MULE) carrier inside is pressure cleaned after its arrival. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2306

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – The Multi-Use Lightweight Equipment, or MULE, carrier is waiting to be moved onto another stand in the high bay in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Jack Pfaller

KSC-08pd2313

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Multi-Use Lightweight Equipment, or MULE, carrier rests on a stand in the high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2296

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the cover of the shipping container is lifted to reveal the Multi-Use Lightweight Equipment (MULE) carrier inside. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2305

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – The Multi-Use Lightweight Equipment, or MULE, carrier is moved into the high bay in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Jack Pfaller

KSC-08pd2311

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lowers the Multi-Use Lightweight Equipment, or MULE, carrier toward a stand in the high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2317

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – The Multi-Use Lightweight Equipment, or MULE, carrier is revealed after its protective cover was removed in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2300

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, the Multi-Use Lightweight Equipment (MULE) carrier awaits a move into the clean-room high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2292

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – A transporter moves the shipping container with the Multi-Use Lightweight Equipment (MULE) carrier toward the open doors of the airlock in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2304

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – The Multi-Use Lightweight Equipment, or MULE, carrier is being moved into the high bay in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Jack Pfaller

KSC-08pd2293

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – The shipping container with the Multi-Use Lightweight Equipment (MULE) carrier inside is moved into the airlock in the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

Identifying priority chronic wasting disease surveillance areas for mule deer in Montana

USGS Publications Warehouse

Russell, Robin E.; Gude, Justin; Anderson, N.J.; Ramsey, Jennifer M.

2015-01-01

Chronic wasting disease (CWD) is a fatal prion disease that affects a variety of ungulate species including mule deer (Odocoileus hemionus). As of 2014, no CWD cases had been reported in free-ranging ungulates in Montana. However, nearby cases in Canada, Wyoming, and the Dakotas indicated that the disease was encroaching on Montana's borders. Mule deer are native and common throughout Montana, and they represent a significant portion of the total hunter-harvested cervids in the state. The arrival of CWD in Montana may have significant ecosystem and socioeconomic impacts as well as potential consequences for wildlife management. We used 18,879 mule deer locations from 892 individual deer collected during 1975–2011 and modeled habitat selection for 7 herds in 5 of the 7 wildlife management regions in Montana. We estimated resource selection functions (RSF) in a Bayesian framework to predict summer and winter habitat preferences for mule deer. We estimated deer abundance from flyover counts for each region, and used the RSF predictions as weights to distribute the deer across the region. We then calculated the distance to the nearest known infected herds. We predicted areas of high risk of CWD infection in mule deer as areas with densities above the median density estimate and within the lowest quartile of distances to known infected herds. We identified these areas, the southeast corner of Montana and the north-central border near Alberta and Saskatchewan, as priority areas for CWD surveillance and management efforts. 

Endemic chronic wasting disease causes mule deer population decline in Wyoming.

PubMed

DeVivo, Melia T; Edmunds, David R; Kauffman, Matthew J; Schumaker, Brant A; Binfet, Justin; Kreeger, Terry J; Richards, Bryan J; Schätzl, Hermann M; Cornish, Todd E

2017-01-01

Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy affecting white-tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), Rocky Mountain elk (Cervus elaphus nelsoni), and moose (Alces alces shirasi) in North America. In southeastern Wyoming average annual CWD prevalence in mule deer exceeds 20% and appears to contribute to regional population declines. We determined the effect of CWD on mule deer demography using age-specific, female-only, CWD transition matrix models to estimate the population growth rate (λ). Mule deer were captured from 2010-2014 in southern Converse County Wyoming, USA. Captured adult (≥ 1.5 years old) deer were tested ante-mortem for CWD using tonsil biopsies and monitored using radio telemetry. Mean annual survival rates of CWD-negative and CWD-positive deer were 0.76 and 0.32, respectively. Pregnancy and fawn recruitment were not observed to be influenced by CWD. We estimated λ = 0.79, indicating an annual population decline of 21% under current CWD prevalence levels. A model derived from the demography of only CWD-negative individuals yielded; λ = 1.00, indicating a stable population if CWD were absent. These findings support CWD as a significant contributor to mule deer population decline. Chronic wasting disease is difficult or impossible to eradicate with current tools, given significant environmental contamination, and at present our best recommendation for control of this disease is to minimize spread to new areas and naïve cervid populations.

Endemic chronic wasting disease causes mule deer population decline in Wyoming

PubMed Central

DeVivo, Melia T.; Edmunds, David R.; Kauffman, Matthew J.; Schumaker, Brant A.; Binfet, Justin; Kreeger, Terry J.; Richards, Bryan J.; Schätzl, Hermann M.; Cornish, Todd E.

2017-01-01

Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy affecting white-tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), Rocky Mountain elk (Cervus elaphus nelsoni), and moose (Alces alces shirasi) in North America. In southeastern Wyoming average annual CWD prevalence in mule deer exceeds 20% and appears to contribute to regional population declines. We determined the effect of CWD on mule deer demography using age-specific, female-only, CWD transition matrix models to estimate the population growth rate (λ). Mule deer were captured from 2010–2014 in southern Converse County Wyoming, USA. Captured adult (≥ 1.5 years old) deer were tested ante-mortem for CWD using tonsil biopsies and monitored using radio telemetry. Mean annual survival rates of CWD-negative and CWD-positive deer were 0.76 and 0.32, respectively. Pregnancy and fawn recruitment were not observed to be influenced by CWD. We estimated λ = 0.79, indicating an annual population decline of 21% under current CWD prevalence levels. A model derived from the demography of only CWD-negative individuals yielded; λ = 1.00, indicating a stable population if CWD were absent. These findings support CWD as a significant contributor to mule deer population decline. Chronic wasting disease is difficult or impossible to eradicate with current tools, given significant environmental contamination, and at present our best recommendation for control of this disease is to minimize spread to new areas and naïve cervid populations. PMID:29049389

Endemic chronic wasting disease causes mule deer population decline in Wyoming

USGS Publications Warehouse

DeVivo, Melia T.; Edmunds, David R.; Kauffman, Matthew J.; Schumaker, Brant A.; Binfet, Justin; Kreeger, Terry J.; Richards, Bryan J.; Schatzl, Hermann M.; Cornish, Todd

2017-01-01

Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy affecting white-tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), Rocky Mountain elk (Cervus elaphus nelsoni), and moose (Alces alces shirasi) in North America. In southeastern Wyoming average annual CWD prevalence in mule deer exceeds 20% and appears to contribute to regional population declines. We determined the effect of CWD on mule deer demography using age-specific, female-only, CWD transition matrix models to estimate the population growth rate (λ). Mule deer were captured from 2010–2014 in southern Converse County Wyoming, USA. Captured adult (≥ 1.5 years old) deer were tested ante-mortem for CWD using tonsil biopsies and monitored using radio telemetry. Mean annual survival rates of CWD-negative and CWD-positive deer were 0.76 and 0.32, respectively. Pregnancy and fawn recruitment were not observed to be influenced by CWD. We estimated λ= 0.79, indicating an annual population decline of 21% under current CWD prevalence levels. A model derived from the demography of only CWD-negative individuals yielded; λ = 1.00, indicating a stable population if CWD were absent. These findings support CWD as a significant contributor to mule deer population decline. Chronic wasting disease is difficult or impossible to eradicate with current tools, given significant environmental contamination, and at present our best recommendation for control of this disease is to minimize spread to new areas and naïve cervid populations.

E3 ubiquitin ligase Mule targets β-catenin under conditions of hyperactive Wnt signaling

PubMed Central

Dominguez-Brauer, Carmen; Khatun, Rahima; Elia, Andrew J.; Thu, Kelsie L.; Ramachandran, Parameswaran; Baniasadi, Shakiba P.; Hao, Zhenyue; Jones, Lisa D.; Haight, Jillian; Sheng, Yi; Mak, Tak W.

2017-01-01

Wnt signaling, named after the secreted proteins that bind to cell surface receptors to activate the pathway, plays critical roles both in embryonic development and the maintenance of homeostasis in many adult tissues. Two particularly important cellular programs orchestrated by Wnt signaling are proliferation and stem cell self-renewal. Constitutive activation of the Wnt pathway resulting from mutation or improper modulation of pathway components contributes to cancer development in various tissues. Colon cancers frequently bear inactivating mutations of the adenomatous polyposis coli (APC) gene, whose product is an important component of the destruction complex that regulates β-catenin levels. Stabilization and nuclear localization of β-catenin result in the expression of a panel of Wnt target genes. We previously showed that Mule/Huwe1/Arf-BP1 (Mule) controls murine intestinal stem and progenitor cell proliferation by modulating the Wnt pathway via c-Myc. Here we extend our investigation of Mule’s influence on oncogenesis by showing that Mule interacts directly with β-catenin and targets it for degradation under conditions of hyperactive Wnt signaling. Our findings suggest that Mule uses various mechanisms to fine-tune the Wnt pathway and provides multiple safeguards against tumorigenesis. PMID:28137882

36 CFR 222.3 - Issuance of grazing and livestock use permits.

Code of Federal Regulations, 2014 CFR

2014-07-01

... be authorized without written permit. (F) Paid or free permits for horses, mules, or burros to...) Free permits for horses, mules, or burros to cooperators who clearly need National Forest System land...

9 CFR 320.1 - Records required to be kept.

Code of Federal Regulations, 2013 CFR

2013-01-01

... engages, for commerce, in the business of slaughtering any cattle, sheep, swine, goats, horses, mules, or... diseased cattle, sheep, swine, goats, horses, mules, or other equines, or parts of the carcasses of any...

36 CFR 222.3 - Issuance of grazing and livestock use permits.

Code of Federal Regulations, 2011 CFR

2011-07-01

... be authorized without written permit. (F) Paid or free permits for horses, mules, or burros to...) Free permits for horses, mules, or burros to cooperators who clearly need National Forest System land...

36 CFR 222.3 - Issuance of grazing and livestock use permits.

Code of Federal Regulations, 2012 CFR

2012-07-01

... be authorized without written permit. (F) Paid or free permits for horses, mules, or burros to...) Free permits for horses, mules, or burros to cooperators who clearly need National Forest System land...

25 CFR 167.6 - Carrying capacities.

Code of Federal Regulations, 2012 CFR

2012-04-01

...) Carrying capacities shall be stated in terms of sheep units yearlong, in the ratio of horses, mules, and..., goats, cattle, horses, mules, and burros one year of age or older shall be counted against the carrying...

9 CFR 320.1 - Records required to be kept.

Code of Federal Regulations, 2012 CFR

2012-01-01

... engages, for commerce, in the business of slaughtering any cattle, sheep, swine, goats, horses, mules, or... diseased cattle, sheep, swine, goats, horses, mules, or other equines, or parts of the carcasses of any...

Cultural Resources Investigations for Libby Reservoir, Lincoln County, Northwest, Montana. Volume 1. Environment, Archaeology, and Land Use Patterns in the Middle Kootenai River Valley.

DTIC Science & Technology

1984-12-01

by rams and ewes to late winter/spring ranges (late March), movement of females to lambing areas and males to salt licks (late May), and finally the...1981:212 of California 10-15 mule Foothills of Montana Wallmo 1981:212 3.5-11 mule Badlands of Montana Wallmo 1981:212 1-5 mule Open prairies of Montana...area compare poorly with many settings of North America. North Dakota and eastern Montana prairies , for example, approximate most closely the summer

9 CFR 355.43 - Scope and applicability of rules of practice.

Code of Federal Regulations, 2014 CFR

2014-01-01

...; INSPECTION, CERTIFICATION, AND IDENTIFICATION AS TO CLASS, QUALITY, QUANTITY, AND CONDITION Mule Meat and Animal Food, Mule Meat By-Product § 355.43 Scope and applicability of rules of practice. The rules of...

Endocrine and ultrasonographic aspects of the oestrous cycle of the mule.

PubMed

Volpe, P; Russo, M; Ianetti, L; Izzo, B

2005-12-03

The blood serum concentrations of progesterone and estradiol-17beta were measured at various stages of the oestrous cycle of seven female mules, and their reproductive tracts were examined ultrasonographically at the same stages.

5. Abandoned mule trail tunnel. 1 mile from intersection with ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. Abandoned mule trail tunnel. 1 mile from intersection with Newfound Gap Road looking SSE. - Great Smoky Mountains National Park Roads & Bridges, Clingmans Dome Road, Between Newfound Gap Road & Clingmans Dome, Gatlinburg, Sevier County, TN

9 CFR 355.43 - Scope and applicability of rules of practice.

Code of Federal Regulations, 2013 CFR

2013-01-01

...; INSPECTION, CERTIFICATION, AND IDENTIFICATION AS TO CLASS, QUALITY, QUANTITY, AND CONDITION Mule Meat and Animal Food, Mule Meat By-Product § 355.43 Scope and applicability of rules of practice. The rules of...

9 CFR 355.43 - Scope and applicability of rules of practice.

Code of Federal Regulations, 2011 CFR

2011-01-01

...; INSPECTION, CERTIFICATION, AND IDENTIFICATION AS TO CLASS, QUALITY, QUANTITY, AND CONDITION Mule Meat and Animal Food, Mule Meat By-Product § 355.43 Scope and applicability of rules of practice. The rules of...

9 CFR 355.43 - Scope and applicability of rules of practice.

Code of Federal Regulations, 2012 CFR

2012-01-01

...; INSPECTION, CERTIFICATION, AND IDENTIFICATION AS TO CLASS, QUALITY, QUANTITY, AND CONDITION Mule Meat and Animal Food, Mule Meat By-Product § 355.43 Scope and applicability of rules of practice. The rules of...

KSC-08pd2307

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane is attached to the Multi-Use Lightweight Equipment, or MULE, carrier to moved the carrier to another stand in the high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2308

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lifts the Multi-Use Lightweight Equipment, or MULE, carrier from a mobile platform to move it to another stand in the high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2309

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lifts the Multi-Use Lightweight Equipment, or MULE, carrier from a mobile platform to move it to another stand in the high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2310

NASA Image and Video Library

2008-08-06

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane lifts the Multi-Use Lightweight Equipment, or MULE, carrier from a mobile platform to move it to another stand in the high bay. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. Photo credit: NASA/Jack Pfaller

KSC-08pd2295

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, an overhead crane is attached to the shipping container with the Multi-Use Lightweight Equipment (MULE) carrier inside. The cover will be removed. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

KSC-08pd2299

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center, workers in the background detach the crane from the cover of the shipping container removed from the Multi-Use Lightweight Equipment (MULE) carrier in the foreground. The MULE is part of the payload for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

Occurrence of antibodies against Toxoplasma gondii and its isolation and genotyping in donkeys, mules, and horses in Brazil.

PubMed

Gennari, Solange M; Esmerini, Patrícia de O; Lopes, Marcos G; Soares, Herbert S; Vitaliano, Sérgio N; Cabral, Aline D; Pena, Hilda F J; Horta, Maurício C; Cavalcante, Paulo H; Fortes, Kleber P; Villalobos, Eliana M C

2015-04-15

The occurrence of antibodies against Toxoplasma gondii was determined in donkeys, mules, and horses from different regions of Brazil. Serum samples from 304 donkeys (67.11%), 118 horses (26.05%), and 31 mules (6.84%) were analyzed by means of the indirect fluorescent antibody test (cutoff=64). Antibodies against T. gondii were detected in 129 equids (28.47%) (82 donkeys, 32 horses, and 15 mules). Tissue samples from 19 seropositive and 50 seronegative animals were obtained in order to isolate the parasite by means of mouse bioassay, and T. gondii was isolated from a donkey. Through genotypic characterization of the isolate, by means of polymerase chain reaction (PCR)-restriction fragment length polymorphism (RFLP) using 11 genotypic markers, the genotype #163 (TgCkBr220), which has already been described in chickens in Brazil, was identified. Copyright © 2015 Elsevier B.V. All rights reserved.

Genetic differences in the serum proteome of horses, donkeys and mules are detectable by protein profiling.

PubMed

Henze, Andrea; Aumer, Franziska; Grabner, Arthur; Raila, Jens; Schweigert, Florian J

2011-10-01

Although horses and donkeys belong to the same genus, their genetic characteristics probably result in specific proteomes and post-translational modifications (PTM) of proteins. Since PTM can alter protein properties, specific PTM may contribute to species-specific characteristics. Therefore, the aim of the present study was to analyse differences in serum protein profiles of horses and donkeys as well as mules, which combine the genetic backgrounds of both species. Additionally, changes in PTM of the protein transthyretin (TTR) were analysed. Serum protein profiles of each species (five animals per species) were determined using strong anion exchanger ProteinChips® (Bio-Rad, Munich, Germany) in combination with surface-enhanced laser desorption ionisation-time of flight MS. The PTM of TTR were analysed subsequently by immunoprecipitation in combination with matrix-assisted laser desorption ionisation-time of flight MS. Protein profiling revealed species-specific differences in the proteome, with some protein peaks present in all three species as well as protein peaks that were unique for donkeys and mules, horses and mules or for horses alone. The molecular weight of TTR of horses and donkeys differed by 30 Da, and both species revealed several modified forms of TTR besides the native form. The mass spectra of mules represented a merging of TTR spectra of horses and donkeys. In summary, the present study indicated that there are substantial differences in the proteome of horses and donkeys. Additionally, the results probably indicate that the proteome of mules reveal a higher similarity to donkeys than to horses.

159. Credit PG&E. Using mules and horses to transport generator ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

159. Credit PG&E. Using mules and horses to transport generator base plate from Anderson, CA, to Northern California's Kilarc powerhouse, c. 1903. - Battle Creek Hydroelectric System, Battle Creek & Tributaries, Red Bluff, Tehama County, CA

25 CFR 167.6 - Carrying capacities.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., mules, and burros 1 to 5; cattle 1 to 4; goats 1 to 1. The latter figure in each case denotes sheep units. Sheep, goats, cattle, horses, mules, and burros one year of age or older shall be counted against...

25 CFR 167.6 - Carrying capacities.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., mules, and burros 1 to 5; cattle 1 to 4; goats 1 to 1. The latter figure in each case denotes sheep units. Sheep, goats, cattle, horses, mules, and burros one year of age or older shall be counted against...

25 CFR 161.1 - What definitions do I need to know?

Code of Federal Regulations, 2014 CFR

2014-04-01

... following: (1) One adult sheep or goat is equivalent to one-fifth (0.20) of an AU; (2) One adult horse, mule..., cattle, sheep, goats, mules, burros, donkeys, and llamas. Management Unit is a subdivision of a...

Letting Be: The Pedagogy of Mule Skinner. The Principal's Storybook: A Special Section

ERIC Educational Resources Information Center

Hood, Bruce L.

1975-01-01

In a discussion of the philosophy of the mythical sage, Mule Skinner, the author argues that education is most effective when teachers do not try to impose their own values and objectives on students. (JG)

8. PHOTOCOPY, 1880 STREET SCENE, called 'MULE TRAIN' (SHOWING INDIAN ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

8. PHOTOCOPY, 1880 STREET SCENE, called 'MULE TRAIN' (SHOWING INDIAN FIREWOOD VENDER WITH HEAD BURDENS OF LIGHT FIREWOOD AND TWO BURROS WITH HEAVIER FIREWOOD LOADS.) - Barrio Libre, West Kennedy & West Seventeenth Streets, Meyer & Convent Avenues, Tucson, Pima County, AZ

27 CFR 9.184 - Trinity Lakes.

Code of Federal Regulations, 2014 CFR

2014-04-01

... continue northwesterly along the contour line across Mule Creek and Snowslide Gulch in section 13, T35N/R9W; continue on the contour line, cross Little Mule Creek in section 18, T35N/R8W, and continue southeasterly...

25 CFR 161.1 - What definitions do I need to know?

Code of Federal Regulations, 2012 CFR

2012-04-01

... following: (1) One adult sheep or goat is equivalent to one-fifth (0.20) of an AU; (2) One adult horse, mule..., cattle, sheep, goats, mules, burros, donkeys, and llamas. Management Unit is a subdivision of a...

25 CFR 161.1 - What definitions do I need to know?

Code of Federal Regulations, 2011 CFR

2011-04-01

... following: (1) One adult sheep or goat is equivalent to one-fifth (0.20) of an AU; (2) One adult horse, mule..., cattle, sheep, goats, mules, burros, donkeys, and llamas. Management Unit is a subdivision of a...

27 CFR 9.184 - Trinity Lakes.

Code of Federal Regulations, 2012 CFR

2012-04-01

... continue northwesterly along the contour line across Mule Creek and Snowslide Gulch in section 13, T35N/R9W; continue on the contour line, cross Little Mule Creek in section 18, T35N/R8W, and continue southeasterly...

27 CFR 9.184 - Trinity Lakes.

Code of Federal Regulations, 2013 CFR

2013-04-01

... continue northwesterly along the contour line across Mule Creek and Snowslide Gulch in section 13, T35N/R9W; continue on the contour line, cross Little Mule Creek in section 18, T35N/R8W, and continue southeasterly...

In-network Coding for Resilient Sensor Data Storage and Efficient Data Mule Collection

NASA Astrophysics Data System (ADS)

Albano, Michele; Gao, Jie

In a sensor network of n nodes in which k of them have sensed interesting data, we perform in-network erasure coding such that each node stores a linear combination of all the network data with random coefficients. This scheme greatly improves data resilience to node failures: as long as there are k nodes that survive an attack, all the data produced in the sensor network can be recovered with high probability. The in-network coding storage scheme also improves data collection rate by mobile mules and allows for easy scheduling of data mules.

Health status of mule deer and white-tailed deer herds on the Rocky Mountain Arsenal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Creekmore, T.E.; Franson, J.C.; Sileo, L.

1994-12-31

The Rocky Mountain Arsenal is a fenced, 6,900-ha Superfund site under remediation by the US Army and the Shell Oil Company. A variety of environmental contaminants including organochlorine pesticides, metals, and nerve-gas-production by-products are in the soil or in the water on the site. The authors evaluated the health of 18 radio-collared deer (13 mule deer [Odocoileus hemionus] and 5 white-tailed deer [O. virginianus]) collected by gunshot. Prior to collection, more than 4,000 locations of the 18 deer were plotted during a period of more than 2 years. Blood samples from the euthanized animals were collected for serologic, hematologic, andmore » contaminant evaluations. Necropsies were preformed and tissues collected for histopathologic examinations and environmental contaminants analyses. Results indicate that the physical conditions of the mule deer were fair/good and of the white-tailed deer were good. Antibody prevalence against epizootic hemorrhagic disease serotype 2 was 85% and bovine virus diarrhea 56%. Two mule deer had severe testicular atrophy, and one of these animals also had antler deformities. Three mule deer had alopecia with dermatitis and hyperkeratosis. Results of heavy metal, and organochlorine pesticide analyses from blood and tissue samples and other analyses will be presented.« less

Infectious Disease and Grouping Patterns in Mule Deer.

PubMed

Mejía Salazar, María Fernanda; Waldner, Cheryl; Stookey, Joseph; Bollinger, Trent K

2016-01-01

Infectious disease dynamics are determined, to a great extent, by the social structure of the host. We evaluated sociality, or the tendency to form groups, in Rocky Mountain mule deer (Odocoileus hemionus hemionus) from a chronic wasting disease (CWD) endemic area in Saskatchewan, Canada, to better understand factors that may affect disease transmission. Using group size data collected on 365 radio-collared mule deer (2008-2013), we built a generalized linear mixed model (GLMM) to evaluate whether factors such as CWD status, season, habitat and time of day, predicted group occurrence. Then, we built another GLMM to determine factors associated with group size. Finally, we used 3 measures of group size (typical, mean and median group sizes) to quantify levels of sociality. We found that mule deer showing clinical signs of CWD were less likely to be reported in groups than clinically healthy deer after accounting for time of day, habitat, and month of observation. Mule deer groups were much more likely to occur in February and March than in July. Mixed-sex groups in early gestation were larger than any other group type in any season. Groups were largest and most likely to occur at dawn and dusk, and in open habitats, such as cropland. We discuss the implication of these results with respect to sociobiology and CWD transmission dynamics.

Evaluation of mule deer crossing structures in Nugget Canyon, Wyoming.

DOT National Transportation Integrated Search

2011-09-01

"Wildlife-vehicle collisions pose a major safety concern to motorists and can be a significant source of mortality for wildlife. A 13- : mile section of Highway 30 in southwest Wyoming has been especially problematic with an average of 130 mule deer ...

Polymorphic integrations of an endogenous gammaretrovirus in the mule deer genome.

PubMed

Elleder, Daniel; Kim, Oekyung; Padhi, Abinash; Bankert, Jason G; Simeonov, Ivan; Schuster, Stephan C; Wittekindt, Nicola E; Motameny, Susanne; Poss, Mary

2012-03-01

Endogenous retroviruses constitute a significant genomic fraction in all mammalian species. Typically they are evolutionarily old and fixed in the host species population. Here we report on a novel endogenous gammaretrovirus (CrERVγ; for cervid endogenous gammaretrovirus) in the mule deer (Odocoileus hemionus) that is insertionally polymorphic among individuals from the same geographical location, suggesting that it has a more recent evolutionary origin. Using PCR-based methods, we identified seven CrERVγ proviruses and demonstrated that they show various levels of insertional polymorphism in mule deer individuals. One CrERVγ provirus was detected in all mule deer sampled but was absent from white-tailed deer, indicating that this virus originally integrated after the split of the two species, which occurred approximately one million years ago. There are, on average, 100 CrERVγ copies in the mule deer genome based on quantitative PCR analysis. A CrERVγ provirus was sequenced and contained intact open reading frames (ORFs) for three virus genes. Transcripts were identified covering the entire provirus. CrERVγ forms a distinct branch of the gammaretrovirus phylogeny, with the closest relatives of CrERVγ being endogenous gammaretroviruses from sheep and pig. We demonstrated that white-tailed deer (Odocoileus virginianus) and elk (Cervus canadensis) DNA contain proviruses that are closely related to mule deer CrERVγ in a conserved region of pol; more distantly related sequences can be identified in the genome of another member of the Cervidae, the muntjac (Muntiacus muntjak). The discovery of a novel transcriptionally active and insertionally polymorphic retrovirus in mammals could provide a useful model system to study the dynamic interaction between the host genome and an invading retrovirus.

Habitat effects on condition of doe mule deer in arid mixed woodland-grassland

USGS Publications Warehouse

Bender, L.C.; Lomas, L.A.; Kamienski, T.

2007-01-01

Productivity of mule deer (Odocoileus hemionus Raf.) populations is closely linked to individual nutritional condition. We modeled body fat of individual does as a function of vegetation cover, composition, and water characteristics of their annual, summer, and winter home ranges in north-central New Mexico. We also modeled home range size as a function of the same characteristics. Levels of body fat were most closely and negatively related to the amount of pinyon-juniper in an individual deer's annual home range (F1,21 = 7.6; P = 0.012; r2 = 0.26). Pinyon-juniper types provided little (combined ground cover of preferred forbs and shrubs = 5.7%) mule deer forage but were included in home ranges in excess of their availability on the landscape, likely because of security cover attributes. Proportion of grasslands in home ranges was most strongly related to both annual (F1,23 = 4.9; P = 0.037; r2 = 0.18) and summer (F2,25 = 5.7; P = 0.009; r2 = 0.31) home range sizes, and home ranges increased as the grassland component increased, indicating that this habitat type was providing little value to mule deer. Grassland (0.2% combined cover of preferred forb and shrub) and montane conifer (3.2% ground cover of preferred forb and shrub) habitat types similarly lacked preferred mule deer food, and grasslands also lacked cover. Most immediate gains in mule deer habitat in north-central New Mexico may be attained by management of pinyon-juniper communities to increase forage quantity and quality while maintaining cover attributes. Gains can also be realized in grasslands, but here management must establish both cover and forage.

Nasal rhinosporidiosis in a mule.

PubMed

Berrocal, Alexis; López, Alfonso

2007-03-01

A mass was removed from the nostril of a mule that exhibited unilateral epistaxis and nasal discharge. Impression smears revealed oval structures consistent with spores of Rhinosporidium seeberi. Microscopically, the mass was composed of fibrovascular granulomatous tissue containing sporangia R. seeberi. Surgical excision and antifungal treatment proved curative.

First molecular characterisation of a Brazilian Burkholderia mallei strain isolated from a mule in 2016.

PubMed

Laroucau, K; Lucia de Assis Santana, V; Girault, G; Martin, B; Miranda da Silveira, P P; Brasil Machado, M; Joseph, M; Wernery, R; Wernery, U; Zientara, S; Madani, N

2018-01-01

We present the first molecular characterisation based on MLVA and SNP analysis of a strain of Burkholderia mallei isolated from a mule found dead in Brazil in 2016. Copyright © 2017 Elsevier B.V. All rights reserved.

Weather conditions associated with autumn migration by mule deer in Wyoming.

PubMed

Rittenhouse, Chadwick D; Mong, Tony W; Hart, Thomas

2015-01-01

Maintaining ecological integrity necessitates a proactive approach of identifying and acquiring lands to conserve unfragmented landscapes, as well as evaluating existing mitigation strategies to increase connectivity in fragmented landscapes. The increased use of highway underpasses and overpasses to restore connectivity for wildlife species offers clear conservation benefits, yet also presents a unique opportunity to understand how weather conditions may impact movement of wildlife species. We used remote camera observations (19,480) from an existing wildlife highway underpass in Wyoming and daily meteorological observations to quantify weather conditions associated with autumn migration of mule deer in 2009 and 2010. We identified minimal daily temperature and snow depth as proximate cues associated with mule deer migration to winter range. These weather cues were consistent across does and bucks, but differed slightly by year. Additionally, extreme early season snow depth or cold temperature events appear to be associated with onset of migration. This information will assist wildlife managers and transportation officials as they plan future projects to maintain and enhance migration routes for mule deer.

Improving residual feed intake of mule progeny of Muscovy ducks: genetic parameters and responses to selection with emphasis on carcass composition and fatty liver quality.

PubMed

Drouilhet, L; Basso, B; Bernadet, M-D; Cornuez, A; Bodin, L; David, I; Gilbert, H; Marie-Etancelin, C

2014-10-01

In France, about 95% of the fatty liver production comes from mule ducks, an infertile hybrid cross between female common ducks (Anas platyrhynchos) and Muscovy drakes (Cairina moschata). As a hybrid, genetic improvement of the performance of mule ducks is achieved by selection of the parental populations. Feed represents two-thirds of the total costs of duck production; thus, the breeders' main concern is to improve the birds' feed efficiency without impairing their capacity to be overfed after the growing period. To obtain insight into this economically important trait, we designed a divergent selection experiment for Muscovy sires on the basis of the residual feed intake (RFI) of their male mule progeny. Residual feed intake represents the fraction of feed intake that cannot be explained by maintenance and production requirements. Data comprised records from generations 0 to 2 with 227 Muscovy sires of 2,016 mule ducks. Growth and fat deposition were measured individually for all mule ducks. Half-sib mule ducks were placed together in 1 small pen, and the feed consumption was recorded for each pen; all half-sibs therefore had the same feed intake estimates. Heritability of RFI was high (0.83 ± 0.42), and after 2 generations of selection, the differences between lines in terms of RFI (contrast of 9.13 g/d, representing 0.76 phenotypic standard deviation; P < 0.0001) and feed conversion ratio (contrast of 0.08, representing 0.28 phenotypic standard deviation; P = 0.0003) were marked. In regard to carcass traits, the low-RFI line (high-efficiency animals) had heavier legs (476 vs. 463 g; P < 0.0001) and magret muscles (268 vs. 262 g; P = 0.001) than the high-RFI line (low-efficiency animals). No differences were observed for either the liver weight or the melting rate between the 2 lines (P > 0.46). Selection on RFI thus improves the feed efficiency of animals without impairing their capacity to produce fatty liver.

Bio-inspired secure data mules for medical sensor network

NASA Astrophysics Data System (ADS)

Muraleedharan, Rajani; Gao, Weihua; Osadciw, Lisa A.

2010-04-01

Medical sensor network consist of heterogeneous nodes, wireless, mobile and wired with varied functionality. The resources at each sensor require to be exploited minimally while sensitive information is sensed and communicated to its access points using secure data mules. In this paper, we analyze the flat architecture, where different functionality and priority information require varied resources forms a non-deterministic polynomial-time hard problem. Hence, a bio-inspired data mule that helps to obtain dynamic multi-objective solution with minimal resource and secure path is applied. The performance of the proposed approach is based on reduced latency, data delivery rate and resource cost.

Assessing cumulative impacts to elk and mule deer in the Salmon River Basin, Idaho

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Neil, T.A.; Witmer, G.W.

1988-01-01

In this paper, we illustrate the method, using the potential for cumulative impacts to elk and mule deer from multiple hydroelectric development in the Salmon River Basin of Idaho. We attempted to incorporate knowledge of elk and mule deer habitat needs into a paradigm to assess cumulative impacts and aid in the regulatory decision making process. Undoubtedly, other methods could be developed based on different needs or constraints, but we offer this technique as a means to further refine cumulative impact assessment. Our approach is divided into three phases: analysis, evaluation, and documentation. 36 refs., 2 figs., 3 tabs.

Evolutionary trajectory of Pack-MULEs is determined by their epigenetic status

USDA-ARS?s Scientific Manuscript database

Acquisition and rearrangement of host genes by transposable elements is one mechanism to increase gene diversity. The rice genome is replete in such sequences and while ~3,000 Pack- Mutator-like transposable elements containing gene sequences (Pack-MULEs) have been identified, their function remains...

Spatial and temporal interactions of elk, mule deer, and cattle.

Treesearch

Priscilla K. Coe; Bruce K. Johnson; Kelley M. Stewart; John G. Kie

2004-01-01

Elk (Cervus elaphus), mule deer (Odocoileus hemionus) and cattle share millions of acres of public and private forests and rangelands across the western United States and Canada. These three species have important social, ecological and economic values. Understanding their interspecific interactions may clarify two recurring...

Mule Deer (Odocoileus hemionus) Movement and Habitat Use Patterns in Relation to Roadways in Northwest Wyoming

DOT National Transportation Integrated Search

2013-10-01

The purpose of this study was to provide the Wyoming Department of Transportation and Wyoming Game and Fish Department with useful information about the patterns of mule deer seasonal habitat use, migration, road crossings, and wildlife-vehicle colli...

9 CFR 355.40 - Plants to furnish information for reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... the inspector assigned to that plant with a statement of the number of pounds of product certified by...] Mule Meat and Animal Food, Mule Meat By-Product ... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Plants to furnish information for...

Endocrine alterations around the time of abortion in mares impregnated with donkey or horse semen.

PubMed

Boeta, M; Zarco, L

2010-08-01

The objective of this study was to monitor and compare the concentrations of equine chorionic gonadotropin (eCG), progesterone and estrone sulphate during normal and failed pregnancies of mares impregnated with donkey or horse semen, relating their individual endocrine profiles to the time of pregnancy loss, and to the histopathologic findings in the aborted fetuses and placenta. Mares (n=54) were used, 32 of them impregnated with donkey semen and 22 impregnated with horse semen. Blood samples were taken twice a week from Day 35 to 120 of pregnancy. Ultrasonographic observations of the fetus were carried out twice a week. The incidence of abortion in mares impregnated with donkey semen (30%) was greater (P<0.05) than the 5% observed in mares impregnated with horse semen. From Week 8 to the end of the sampling period, the mean progesterone concentrations of mares with normal mule pregnancies were less (P<0.05) than those of mares with normal pregnancies with equine fetuses. The concentrations of eCG were less (P<0.05) in mule pregnancies from Week 6. Estrone sulphate concentrations were only different (P<0.05) between types of pregnancy on Weeks 13 and 14, being in this case greater with the mule pregnancies. Most of the abortions of mule fetuses were associated with lesser progesterone concentrations than the average for mares with successful mule pregnancies. Four of the abortions of mule fetuses and the only abortion of horse fetus occurred in mares with lesser progesterone and very low eCG concentrations, and were classified as caused by luteal impairment secondary to eCG deficiency; estrone sulphate concentrations were less than normal or absent before these abortions. Two mares aborted after several weeks of low progesterone concentrations in the presence of eCG concentrations that were normal for mule pregnancies, suggesting primary luteal deficiency. In three mares carrying a mule fetus, the concentrations of progesterone and estrone sulphate decreased abruptly immediately before fetal death, suggesting luteolysis due to active prostaglandin F2 alpha (PGF2alpha) secretion. It is concluded that the greater incidence of abortion in mares impregnated by donkeys is associated with different kinds of luteal malfunction. Deficiency of eCG may be a primary cause of many of these cases, either by failing to stimulate enough luteal progesterone secretion and/or by failing to protect the corpora lutea (CL) of pregnancy from endogenous PGF2alpha secretion. Copyright (c) 2010 Elsevier B.V. All rights reserved.

Effects of Cougar Predation and Nutrition on Mule Deer Population Declines in the Intermountain Province of the Columbia Basin, 2001-2002 Annual Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wielgus, Robert B.; Shipley, Lisa

2002-07-01

Construction of the Grand Coulee and Chief Joseph dams has resulted in inundation and loss of 29,125 total habitat units for mule deer and irrigation agriculture in many parts the Intermountain Province (IM) of the Columbia Basin. Mule deer in the Shrub-Steppe are ranked high priority target species for mitigation and management and are declining in most portions of the subbasins of the IM. Reasons for the decline are unknown but believed to be related to habitat changes resulting from dams and irrigation agriculture. White-tailed deer are not ranked as target species and are believed to be increasing throughout themore » basin because of habitat changes brought about by the dams and irrigation agriculture. Recent research (1997-2000) in the NE IM and adjacent Canadian portions of the Columbia Basin (conducted by this author and funded by the Columbia Basin Fish & Wildlife Compensation Program B.C.), suggest that the increasing white-tailed deer populations (because of dams and irrigation agriculture) are resulting in increased predation by cougars on mule deer (apparent competition or alternate prey hypothesis). The apparent competition hypothesis predicts that as alternate prey (white-tailed deer) densities increase, so do densities of predators, resulting in increased incidental predation on sympatric native prey (mule deer). Apparent competition can result in population declines and even extirpation of native prey in some cases. Such a phenomenon may account for declines of mule deer in the IM and throughout arid and semi-arid West where irrigation agriculture is practiced. We will test the apparent competition hypothesis by conducting a controlled, replicated ''press'' experiment in at least 2 treatment and 2 control areas of the IM subbasins by reducing densities of white-tailed deer and observing any changes in cougar predation on mule deer. Deer densities will be monitored by WADFW personnel using annual aerial surveys and/or other trend indices. Predation rates and population growth rates of deer will be determined using radio telemetry. Changes in cougar functional (kills/unit time), aggregative (cougars/unit area), numerical (offspring/cougar), and total (predation rate) responses on deer will also be monitored using radio telemetry. The experiment will be conducted and completed over a period of 5 years. Results will be used to determine the cause and try to halt the mule deer population declines. Results will also guide deer mitigation and management in the IM and throughout the North American West.« less

Effects of Cougar Predation and Nutrition on Mule Deer Population Declines in the IM Province of the Columbia Basin, Annual Report 2002-2003.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wielgus, Robert; Shipley, Lisa; Myers, Woodrow

2003-09-01

Construction of the Grand Coulee and Chief Joseph dams has resulted in inundation and loss of 29,125 total habitat units for mule deer and irrigation agriculture in many parts the Intermountain Province (IM) of the Columbia Basin. Mule deer in the Shrub-Steppe are ranked high priority target species for mitigation and management and are declining in most portions of the sub basins of the IM. Reasons for the decline are unknown but believed to be related to habitat changes resulting from dams and irrigation agriculture. White-tailed deer are believed to be increasing throughout the basin because of habitat changes broughtmore » about by the dams and irrigation agriculture. Recent research (1997-2000) in the NE IM and adjacent Canadian portions of the Columbia Basin (conducted by this author and funded by the Columbia Basin Fish & Wildlife Compensation Program B.C.), suggest that the increasing white-tailed deer populations (because of dams and irrigation agriculture) are resulting in increased predation by cougars on mule deer (apparent competition or alternate prey hypothesis). The apparent competition hypothesis predicts that as alternate prey (white-tailed deer) densities increase, so do densities of predators, resulting in increased incidental predation on sympatric native prey (mule deer). Apparent competition can result in population declines and even extirpation of native prey in some cases. Such a phenomenon may account for declines of mule deer in the IM and throughout arid and semi-arid West where irrigation agriculture is practiced. We will test the apparent competition hypothesis by conducting a controlled, replicated 'press' experiment in at least 2 treatment and 2 control areas of the IM sub basins by reducing densities of white-tailed deer and observing any changes in cougar predation on mule deer. Deer densities will be monitored by WADFW personnel using annual aerial surveys and/or other trend indices. Predation rates and population growth rates of deer will be determined using radio telemetry. Changes in cougar functional (kills/unit time), aggregative (cougars/unit area), numerical (offspring/cougar), and total (predation rate) responses on deer will also be monitored using radio telemetry. The experiment will be conducted and completed over a period of 5 years. Results will be used to determine the cause and try to halt the mule deer population declines. Results will also guide deer mitigation and management in the IM and throughout the North American West.« less

Genes involved in the establishment of hepatic steatosis in Muscovy, Pekin and mule ducks.

PubMed

Tavernier, Annabelle; Davail, Stéphane; Ricaud, Karine; Bernadet, Marie-Dominique; Gontier, Karine

2017-01-01

Our main objectives were to determine the genes involved in the establishment of hepatic steatosis in three genotypes of palmipeds. To respond to this question, we have compared Muscovy ducks, Pekin ducks and their crossbreed the mule duck fed ad libitum or overfed. We have shown a hepatic overexpression of fatty acid synthase (FAS) and di-acyl glycerol acyl transferase 2 (DGAT2) in overfed individuals, where DGAT2 seemed to be more regulated. This increase in lipogenesis genes is associated with a decrease of lipoprotein formation in Muscovy and mule ducks, especially apolipoprotein B (ApoB) and Microsomal Triglyceride Transfer Protein (MTTP), leading to lipid accumulation in liver. In Pekin ducks, MTTP expression is upregulated suggesting a better hepatic lipids exportation. Regarding lipids re-uptake, fatty acid-binding protein 4 and very-low-density-lipoprotein receptor are overexpressed in liver of mule ducks at the end of the overfeeding period. This phenomenon puts light on a mechanism unknown until today. In fact, mule can incorporate more lipids in liver than the two other genotypes leading to an intensified hepatic steatosis. To conclude, our results confirmed the genotype variability to overfeeding. Furthermore, similar observations are already described in non-alcoholic fatty liver disease in human, and ask if ducks could be an animal model to study hepatic triglyceride accumulation.

Merogonic stages of Theileria cervi in mule deer (Odocoileus hemionus).

PubMed

Wood, Jason; Johnson, Eileen M; Allen, Kelly E; Campbell, Gregory A; Rezabek, Grant; Bradway, Daniel S; Pittman, Louis L; Little, Susan E; Panciera, Roger J

2013-09-01

In February 2012, 12 farmed mule deer (Odocoileus hemionus) were moved from a facility in southwestern Oklahoma to a facility in southeastern Oklahoma that housed 100 farmed white-tailed deer (Odocoileus virginianus). Between the third and fifth weeks, 9 of the 12 mule deer had died, 4 of which were submitted for necropsy. The deer were heavily infested with Amblyomma americanum (lone star ticks). Hematologic data from 1 deer revealed severe anemia, leukocytosis, and intraerythrocytic hemoparasites consistent with Theileria spp. Microscopically, the liver, lymph nodes, and spleen contained multifocally distributed, enlarged monocytic cells whose cytoplasm was replaced by developing meronts in various stages of merogony. It appears that, upon arrival, the Theileria cervi-naïve mule deer became infested with large numbers of Theileria-infected lone star ticks leading to massive exposure of the mule deer to sporozoites of the protozoan, resulting in an acute hemolytic crisis and fatalities. The merogonic stages of T. cervi are also described. The lack of earlier reports of merogony may be due to the fact that only a single, short-lived, merogonic cycle follows exposure to sporozoites and thus merogonic stages are demonstrable for only a short period. Polymerase chain reaction testing of paraffin-embedded tissue yielded a 507-bp amplicon sequence that was 100% identical with the sequence of T. cervi previously reported from white-tailed deer in Oklahoma and from elk in Wisconsin and Indiana.

Metformin enhances TRAIL-induced apoptosis by Mcl-1 degradation via Mule in colorectal cancer cells.

PubMed

Park, Seong Hye; Lee, Dae-Hee; Kim, Jung Lim; Kim, Bo Ram; Na, Yoo Jin; Jo, Min Jee; Jeong, Yoon A; Lee, Suk-Young; Lee, Sun Il; Lee, Yong Yook; Oh, Sang Cheul

2016-09-13

Metformin is an anti-diabetic drug with a promising anti-cancer potential. In this study, we show that subtoxic doses of metformin effectively sensitize human colorectal cancer (CRC) cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL), which induces apoptosis. Metformin alone did not induce apoptosis, but significantly potentiated TRAIL-induced apoptosis in CRC cells. CRC cells treated with metformin and TRAIL showed activation of the intrinsic and extrinsic pathways of caspase activation. We attempted to elucidate the underlying mechanism, and found that metformin significantly reduced the protein levels of myeloid cell leukemia 1 (Mcl-1) in CRC cells and, the overexpression of Mcl-1 inhibited cell death induced by metformin and/or TRAIL. Further experiments revealed that metformin did not affect mRNA levels, but increased proteasomal degradation and protein stability of Mcl-1. Knockdown of Mule triggered a significant decrease of Mcl-1 polyubiquitination. Metformin caused the dissociation of Noxa from Mcl-1, which allowed the binding of the BH3-containing ubiquitin ligase Mule followed by Mcl-1ubiquitination and degradation. The metformin-induced degradation of Mcl-1 required E3 ligase Mule, which is responsible for the polyubiquitination of Mcl-1. Our study is the first report indicating that metformin enhances TRAIL-induced apoptosis through Noxa and favors the interaction between Mcl-1 and Mule, which consequently affects Mcl-1 ubiquitination.

Spatial partitioning by mule deer and elk in relation to traffic.

Treesearch

Michael J. Wisdom; Norman J. Cimon; Bruce K. Johnson; Edward O. Garton; Jack Ward. Thomas

2004-01-01

Elk (Cervus elaphus) and mule deer (Odocoileus hemionus) have overlapping ranges on millions of acres of forests and rangelands in western North America. Accurate prediction of their spatial distributions within these ranges is essential to effective land-use planning, stocking allocation and population management (Wisdom and...

Diet composition, dry matter intake and diet overlap of mule deer, elk and cattle.

Treesearch

Scott L. Findholt; Bruce K. Johnson; Daalkhaijav Damiran; Tim DelCurto; John G. Kie

2004-01-01

Mule deer (Odocoileus hemionus), elk (Cervus elaphus) and cattle share rangeland throughout much of interior western North America. Considerable debate exists about the degree to which facilitation or competition occurs for forage between these three species (Nelson 1982, Wisdom and Thomas 1996, Miller 2002).

Movements and habitat use of rocky mountain elk and mule deer.

Treesearch

Alan A. Ager; Haiganoush K. Preisler; Bruce K. Johnson; John G. Kie

2004-01-01

Understanding how ungulates use large landscapes to meet their daily needs for food, security and other resources is critical to wildlife management and conservation practices (Johnson et al. 2002). For ungulates like Rocky Mountain elk (Gems elaphui) and mule deer (Odocoileus hemionus), landscapes are a mosaic of different...

KSC-08pd2288

NASA Image and Video Library

2008-08-05

CAPE CANAVERAL, Fla. – The Multi-Use Lightweight Equipment (MULE) carrier arrives at NASA's Kennedy Space Center for the fifth and final shuttle servicing mission to NASA's Hubble Space Telescope, STS-125. The MULE carrier will join the Flight Support System, the Super Lightweight Interchangeable Carrier and the Orbital Replacement Unit Carrier in the Payload Hazardous Servicing Facility where the Hubble payload is being prepared for launch. The Relative Navigation Sensors and the New Outer Blanket Layers will be on the MULE. The payload is scheduled to go to Launch Pad 39A in mid-September to be installed into Atlantis' payload bay. Atlantis is targeted to launch Oct. 8 at 1:34 a.m. EDT. .Photo credit: NASA/Amanda Diller

Landscape development and mule deer habitat in Central Oregon

Treesearch

James A. Duncan; Theresa Burcsu

2012-01-01

This research explored the ecological consequences of rural residential development and different management regimes on a tract of former industrial timberland in central Oregon known as the Bull Springs. Forage quality and habitat suitability models for mule deer (Odocoileus hemionus) winter range were joined to the outputs of a spatially explicit...

Habitat characteristics of the Silver Lake mule deer range.

Treesearch

J. Edward Dealy

1971-01-01

Twenty-one ecosystems of the Silver Lake mule deer range in northern Lake County, Oregon, are described by site, vegetation, and soil. Discussions are included on ecosystem interrelationships, habitat value for game, and habitat manipulation. A field key to ecosystems has been developed using vegetation characteristics easily identifiable on the ground.

Does targeted grazing with small ruminants influence subsequent patch use by mule deer and cattle?

USDA-ARS?s Scientific Manuscript database

Small ruminants are increasingly being used in controlled grazing programs to target undesirable vegetation. It has not been determined how targeted juniper browsing affects subsequent use of those patches by cattle and wildlife. To determine whether cattle or mule deer used or avoided patches that ...

"Sis Cat" as Ethnographer: Self-Presentation and Self-Inscription in Zora Neale Hurston's "Mules and Men."

ERIC Educational Resources Information Center

Boxwell, D. A.

1992-01-01

Examines Zora Neale Hurston's work, particularly her collection of folklore and ethnography of the American South, "Mules and Men." Looks at the author's role, the ways the ethnographer inscribes herself into the text, and speculates about Hurston's understanding of the limits of the impersonal researcher. (JB)

25 CFR 161.1 - What definitions do I need to know?

Code of Federal Regulations, 2010 CFR

2010-04-01

... following: (1) One adult sheep or goat is equivalent to one-fifth (0.20) of an AU; (2) One adult horse, mule..., cattle, sheep, goats, mules, burros, donkeys, and llamas. Management Unit is a subdivision of a... management plan is a statement of management objectives for grazing, farming, or other agriculture management...

Multiple Event Localization in a Sparse Acoustic Sensor Network Using UAVs as Data Mules

DTIC Science & Technology

2012-12-01

necessarily reflect the position or the policy of the Government , and no official endorsement should be inferred. Path Acoustic Sensor Communication Footprint...a Microhard radio to forward the ToAs to the mule-UAV. Two Procerus Unicorn UAVs were used with different payloads. The imaging- UAV was equipped

Landscape simulation of foraging by elk, mule deer, and cattle on summer range.

Treesearch

Alan A. Ager; Bruce K. Johnson; Priscilla K. Coe; Michael J. Wisdom

2004-01-01

Cattle, mule deer (Odocoileus hemionus) and elk (Cervus elaphus) share more area of spring, summer and fall range than any other combination of wild and domestic ungulates in western North America (Wisdom and Thomas 1996). Not surprisingly, conflicts over perceived competition for forage have a long history, yet knowledge about...

Mule deer and elk winter diet as an indicator of habitat competition

Treesearch

Michael R. Frisina; Carl L. Wambolt; W. Wyatt Fraas; Glen Guenther

2008-01-01

Mule deer (Odocoileus hemionus) populations have gradually declined in recent decades, while elk (Cervus elaphus) have often increased throughout their common ranges. The cause is uncertain and a source of debate. Increasing elk numbers on these ungulate winter ranges may be causing competition for resources. We contrast winter...

Overview of the Starkey Project: mule deer and elk research for management benefits.

Treesearch

Michael J. Wisdom; Mary M. Rowland; Bruce K. Johnson; Brian L. Dick

2004-01-01

Managers have long been concerned about the welfare of mule deer (Odocoileus hemionus) and elk (Cervus elaphus) on public lands in the western United States. These two species generate millions of dollars annually to state wildlife agencies from sales of hunting licenses, and elk viewing generates millions of additional dollars...

First detection and molecular characterization of Echinococcus equinus in a mule in Turkey.

PubMed

Simsek, Sami; Cevik, Aydin

2014-10-01

Cystic echinococcosis is a zoonotic disease with a cosmopolital distribution. It is caused by the larval stages (metacestodes) of the parasite Echinococcus granulosus which infects different animal species. In this report, we present a case of E. granulosus infection in a mule and molecular characterization of the cyst. For this purpose parasite material was collected from the liver of a necropsied mule. DNA was isolated and PCR amplification of mitochondrial 12S rRNA as well as partial sequencing of mitochondrial cytochrome c oxidase subunit 1 (mt-CO1) genes were performed. Six unilocular cysts, filled with clear fluid were found in the liver and spleen. All cysts were found to be fertile. The 12S rRNA-PCR did not yield any band while mt-CO1-PCR yielded a 446 bp sized amplification product. Sequence corresponding to mt-CO1 gene was identical to a sequence reported for E. equinus (formerly G4) (Genbank accession number: KC953029). This is the first record of E. equinus as a cause of cystic echinococcosis in a mule in Turkey.

Short Communication Quick method for identifying horse (Equus caballus) and donkey (Equus asinus) hybrids.

PubMed

Franco, M M; Santos, J B F; Mendonça, A S; Silva, T C F; Antunes, R C; Melo, E O

2016-09-23

The domestication of the Equus genus 5000-6000 years ago has influenced the history of human civilization. As soon as horse and donkey species had been domesticated, they were crossbred, producing humanity's first documented attempt at animal genome manipulation. Since then, the mule (male donkey x female horse) and the reciprocal cross (the hinny, male horse x female donkey) have been the most common equine hybrids in the world. Due to their hybrid vigor, mules and hinnies have been intensively used for carrying loads and people and for tilling the land. Despite their importance, visual distinction of mules and hinnies is difficult due to high phenotypic resemblance. However, the distinction between these two hybrids is of pivotal importance for equid breeders and ranchers. In this study, an easy, low-cost, effective, and fast multiplex-polymerase chain reaction method was developed to distinguish the maternal origin of mules and hinnies, targeting the hyper-variable mitochondrial DNA D-loop region. This methodology can help breeders, ranchers, animal science professionals, and researchers manage their equine herds with more confidence and precision.

Ubiquitylation-dependent regulation of NEIL1 by Mule and TRIM26 is required for the cellular DNA damage response.

PubMed

Edmonds, Matthew J; Carter, Rachel J; Nickson, Catherine M; Williams, Sarah C; Parsons, Jason L

2017-01-25

Endonuclease VIII-like protein 1 (NEIL1) is a DNA glycosylase involved in initiating the base excision repair pathway, the major cellular mechanism for repairing DNA base damage. Here, we have purified the major E3 ubiquitin ligases from human cells responsible for regulation of NEIL1 by ubiquitylation. Interestingly, we have identified two enzymes that catalyse NEIL1 polyubiquitylation, Mcl-1 ubiquitin ligase E3 (Mule) and tripartite motif 26 (TRIM26). We demonstrate that these enzymes are capable of polyubiquitylating NEIL1 in vitro, and that both catalyse ubiquitylation of NEIL1 within the same C-terminal lysine residues. An siRNA-mediated knockdown of Mule or TRIM26 leads to stabilisation of NEIL1, demonstrating that these enzymes are important in regulating cellular NEIL1 steady state protein levels. Similarly, a mutant NEIL1 protein lacking residues for ubiquitylation is more stable than the wild type protein in vivo We also demonstrate that cellular NEIL1 protein is induced in response to ionising radiation (IR), although this occurs specifically in a Mule-dependent manner. Finally we show that stabilisation of NEIL1, particularly following TRIM26 siRNA, contributes to cellular resistance to IR. This highlights the importance of Mule and TRIM26 in maintaining steady state levels of NEIL1, but also those required for the cellular DNA damage response. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

The effect of a topical anaesthetic formulation, systemic flunixin and carprofen, singly or in combination, on cortisol and behavioural responses of Merino lambs to mulesing.

PubMed

Paull, D R; Lee, C; Colditz, I G; Atkinson, S J; Fisher, A D

2007-03-01

To determine the pain responses of lambs to mulesing, and the effectiveness of potential analgesic treatments. Merino lambs (n=64) were allocated at 5 weeks of age to eight treatment groups: 1) sham mules; 2) conventional mules; 3) topical anaesthetic, incorporating lignocaine, bupivicaine, adrenaline and cetrimide, applied immediately after mulesing; 4) flunixin + topical anaesthetic, with flunixin administered 2.5 mg/kg s.c. 90 min before mulesing; 5) carprofen + topical anaesthetic, with carprofen administered 4 mg/kg s.c. 90 min before mulesing; 6) carprofen, administered as above; 7) flunixin, administered as above; and 8) carprofen + flunixin, administered as above. Plasma cortisol was measured at 0, 0.5, 6, 12 and 24 h relative to mulesing. Animal behaviour, including posture, was recorded for 12 h after mulesing. The conventional mules lambs exhibited large increases in plasma cortisol, reduced lying and increased standing with a hunched back compared with sham mules animals. Topical anaesthetic reduced the cortisol peak to mulesing and hunched standing, and increased lying compared with the conventional mules treatment, but generally did not result in values equivalent to sham mules animals. Carprofen, flunixin, and carprofen + flunixin treatments did not reduce the cortisol response to mulesing but substantially ameliorated some changes in behavioural postures. Flunixin + topical anaesthetic reduced the cortisol peak following mulesing and substantially ameliorated most changes in behavioural postures. Carprofen + topical anaesthetic abolished the cortisol peak following mulesing and substantially ameliorated most changes in behavioural postures. All mulesed animals lost weight in the week after mulesing regardless of analgesic administration, but there were no significant differences in growth rate between any of the eight treatments over the 3 weeks after mulesing. Analgesics can moderate the pain response of lambs to mulesing. The welfare outcome for lambs of mulesing could be improved by use of a combination of local anaesthetic and long acting non-steroidal anti-inflammatory drug.

Guaiphenesin-ketamine-xylazine infusion to maintain anesthesia in mules undergoing field castration.

PubMed

Vullo, Cecilia; Carluccio, Augusto; Robbe, Domenico; Meligrana, Marina; Petrucci, Linda; Catone, Giuseppe

2017-10-11

In order to determine whether a combination of guaiphenesin, ketamine and xylazine can induce safe and satisfactory anaesthesia in mules undergoing field castration, eight healthy adult intact male mules were employed. They were premedicated with intravenous (IV) xylazine (1.3 mg/kg); an additional dose of xylazine (0.3 mg/kg IV) was administered in case of inadequate depth of sedation. Anaesthesia was induced with IV thiopental (6 mg/kg). The quality of sedation and induction was recorded. Anaesthesia was maintained with an infusion of guaiphenesin (50 mg/mL), ketamine (2 mg/mL) and xylazine (1 mg/mL) (GKX). The spermatic cord of each testis was infiltrated with 5 mL of 2% lidocaine. During anaesthesia heart rate (HR), respiratory rate (RR), rectal temperature (RT) and haemoglobin oxygen saturation (SpO 2 ) were measured every 5 min. The data were analysed with simple one-way analysis of variance (ANOVA). A P value < 0.05 was considered statistically significant. Time of anesthesia, time of surgery and time of recovery were recorded. Only one mule required an additional dose of xylazine to achieve a satisfactory depth of sedation. Thiopental at the dose of 6 mg/kg IV resulted in smooth induction and lateral recumbency in all animals. GKX provided adequate anaesthesia to perform castration in all mules. Muscle relaxation was deemed adequate and physiological variables remained stable and within references values during the anaesthesia and did not change in response to surgical stimulation. Time (mean ± standard deviation) from the end of the infusion to sternal recumbency and time from sternal recumbency to standing were 27.7 ± 4.6 and 30.1 ± 7.7 min, respectively. The combination of xylazine, thiopental and GKX provides satisfactory short-term anaesthesia in mules undergoing field castration.

Behavior of mule deer on the Keating Winter Range.

Treesearch

W.B. Fowler; J.E. Dealy

1987-01-01

Observations are presented from 4 years of record, 1976 to 1979, on behavior of mule deer (Odocoileus hemionus) in relation to site variables on the Keating Winter Range in northeastern Oregon. Analyses of animal use per unit area showed that the preferential selection of cells was related primarily to static site variables and secondarily to...

Nutritive value of mule deer forages on ponderosa pine summer range in Arizona

Treesearch

P. J. Urness; D. J. Neff; R. K. Watkins

1975-01-01

Chemical analyses and apparent in vitro dry matter digestibilities were obtained for mule deer (Odocoileus hemionus) forages appearing in monthly diets. Relative values among individual forage species were calculated based upon nutrient contents and percentage composition in the diet. These data provide land managers with the means to more precisely assess some impacts...

"Forty Acres and a Mule" as a Pedagogical Motif

ERIC Educational Resources Information Center

Burch, Kerry

2008-01-01

This essay revisits an iconic yet now languishing phrase in United States political culture--"Forty Acres and a Mule"--to clarify the meaning of freedom and to assess the contemporary meaning of its betrayal by the U.S. government immediately after the Civil War. Among the few citizens for whom the phrase still retains a semblance of…

Seasonal neighbors: residential development encroaches on mule deer winter range in central Oregon

Treesearch

Marie Oliver; Jeff Kline

2012-01-01

Mule deer populations in central Oregon are in decline, largely because of habitat loss. Several factors are likely contributors. Encroaching juniper and invasive cheatgrass are replacing deer forage with high nutritional value, such as bitterbrush and sagebrush. Fire suppression and reduced timber harvests mean fewer acres of early successional forest, which also...

Forage selection by mule deer: does niche breadth increase with population density.

Treesearch

M.C. Nicholson; R.T. Bowyer; J.G. Kie

2006-01-01

Effects of population density of mule deer Odocoileus hemionus on forage selection were investigated by comparing diet characteristics of two subpopulations of deer in southern California, USA, that differed in population density during winter. Quality of diet for deer, as indexed by faecal crude protein, was higher at the low-density site than at...

KSC-2009-2708

NASA Image and Video Library

2009-04-16

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Multi-Use Lightweight Equipment, or MULE, carrier is lowered into the payload canister where it will be installed. The MULE contains hardware for the STS-125 mission to service NASA's Hubble Space Telescope. The carrier will deliver the MULE and other carriers to Launch Pad 39A for installation into Atlantis' payload bay. Atlantis' 11-day flight is targeted for launch May 12. The mission will include five spacewalks in which astronauts will refurbish and upgrade the telescope with state-of-the-art science instruments. As a result, Hubble's capabilities will be expanded and its operational lifespan extended through at least 2014. Photo credit: NASA/Tim Jacobs

KSC-2009-2705

NASA Image and Video Library

2009-04-16

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Multi-Use Lightweight Equipment, or MULE, carrier is moved toward the payload canister where it will be installed. The MULE contains hardware for the STS-125 mission to service NASA's Hubble Space Telescope. The carrier will deliver the MULE and other carriers to Launch Pad 39A for installation into Atlantis' payload bay. Atlantis' 11-day flight is targeted for launch May 12. The mission will include five spacewalks in which astronauts will refurbish and upgrade the telescope with state-of-the-art science instruments. As a result, Hubble's capabilities will be expanded and its operational lifespan extended through at least 2014. Photo credit: NASA/Tim Jacobs

KSC-2009-2707

NASA Image and Video Library

2009-04-16

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Multi-Use Lightweight Equipment, or MULE, carrier is lowered toward the payload canister where it will be installed. The MULE contains hardware for the STS-125 mission to service NASA's Hubble Space Telescope. The carrier will deliver the MULE and other carriers to Launch Pad 39A for installation into Atlantis' payload bay. Atlantis' 11-day flight is targeted for launch May 12. The mission will include five spacewalks in which astronauts will refurbish and upgrade the telescope with state-of-the-art science instruments. As a result, Hubble's capabilities will be expanded and its operational lifespan extended through at least 2014. Photo credit: NASA/Tim Jacobs

KSC-2009-2706

NASA Image and Video Library

2009-04-16

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Multi-Use Lightweight Equipment, or MULE, carrier is moved toward the payload canister where it will be installed. The MULE contains hardware for the STS-125 mission to service NASA's Hubble Space Telescope. The carrier will deliver the MULE and other carriers to Launch Pad 39A for installation into Atlantis' payload bay. Atlantis' 11-day flight is targeted for launch May 12. The mission will include five spacewalks in which astronauts will refurbish and upgrade the telescope with state-of-the-art science instruments. As a result, Hubble's capabilities will be expanded and its operational lifespan extended through at least 2014. Photo credit: NASA/Tim Jacobs

Regulation of human MutYH DNA glycosylase by the E3 ubiquitin ligase mule.

PubMed

Dorn, Julia; Ferrari, Elena; Imhof, Ralph; Ziegler, Nathalie; Hübscher, Ulrich

2014-03-07

Oxidation of DNA is a frequent and constantly occurring event. One of the best characterized oxidative DNA lesions is 7,8-dihydro-8-oxoguanine (8-oxo-G). It instructs most DNA polymerases to preferentially insert an adenine (A) opposite 8-oxo-G instead of the appropriate cytosine (C) thus showing miscoding potential. The MutY DNA glycosylase homologue (MutYH) recognizes A:8-oxo-G mispairs and removes the mispaired A giving way to the canonical base excision repair that ultimately restores undamaged guanine (G). Here we characterize for the first time in detail a posttranslational modification of the human MutYH DNA glycosylase. We show that MutYH is ubiquitinated in vitro and in vivo by the E3 ligase Mule between amino acids 475 and 535. Mutation of five lysine residues in this region significantly stabilizes MutYH, suggesting that these are the target sites for ubiquitination. The endogenous MutYH protein levels depend on the amount of expressed Mule. Furthermore, MutYH and Mule physically interact. We found that a ubiquitination-deficient MutYH mutant shows enhanced binding to chromatin. The mutation frequency of the ovarian cancer cell line A2780, analyzed at the HPRT locus can be increased upon oxidative stress and depends on the MutYH levels that are regulated by Mule. This reflects the importance of tightly regulated MutYH levels in the cell. In summary our data show that ubiquitination is an important regulatory mechanism for the essential MutYH DNA glycosylase in human cells.

Home range and habitat selection patterns of mule deer in a restoration-treated ponderosa pine forest

Treesearch

R. Fenner Yarborough; Catherine S. Wightman

2008-01-01

(Please note, this is an abstract only) Forest restoration treatments are currently being conducted throughout the state of Arizona. Restoration treatments open the existing forest structure and may improve foraging habitat for mule deer (Odocoileus hemionus) but may reduce the suitability of day bed sites or decrease fawn recruitment due to removal of sufficient...

Observations of captive Rocky Mountain mule deer behavior

DOE Office of Scientific and Technical Information (OSTI.GOV)

Halford, D.K.; Arthur, W.J. III; Alldredge, A.W.

1987-01-31

Observations were made near Fort Collins, Colorado on the behavior of a captive herd of Rocky Mountain mule deer (Odocoileus hemionus hemionus). Comparisons in general behavior patterns were made between captive and wild deer. Similar behavior was exhibited by captive and wild deer. Captive deer (as well as other species) may be useful for study of certain behavioral aspects of their wild counterparts.

Multi-Modal Interaction for Robotic Mules

DTIC Science & Technology

2014-02-26

Multi-Modal Interaction for Robotic Mules Glenn Taylor, Mike Quist, Matt Lanting, Cory Dunham , Patrick Theisen, Paul Muench Abstract...Taylor, Mike Quist, Matt Lanting, Cory Dunham , and Patrick Theisen are with Soar Technology, Inc. (corresponding author: 734-887- 7620; email: glenn...soartech.com; quist@soartech.com; matt.lanting@soartech.com; dunham @soartech.com; patrick.theisen@soartech.com Paul Muench is with US Army TARDEC

Use of curlleaf mountain-mahogany by mule deer on a transition range.

Treesearch

J. Edward Dealy; Paul J. Edgerton; Wayne G. Williams

1986-01-01

Using the pellet-group sampling method, we concluded that migrating mule deer showed no preference in use between two ratios of curlleaf mountain-mahogany cover and openings on a northern California transition range. Where there is a need to develop forage openings in transition habitats dominated by dense thickets of curlleaf mountain-mahogany, manipulation of cover...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Efroymson, Rebecca Ann; Hargrove, William Walter; Suter, Glenn

A multi-stressor risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework. The focus of the assessment was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, M60-A1 tanks. This paper focuses on the wildlife risk assessment for the helicopter overflight. The primary stressors were sound and the view of the aircraft. Exposure to desert mule deer (Odocoileus hemionus crooki) was quantified using Air Force sound contour programs NOISEMAP and MR_NMAP, which gave very different results. Slant distance from helicopters to deermore » was also used as a measure of exposure that integrated risk from sound and view of the aircraft. Exposure-response models for the characterization of effects consisted of behavioral thresholds in sound exposure level or maximum sound level units or slant distance. Available sound thresholds were limited for desert mule deer, but a distribution of slant-distance thresholds was available for ungulates. The risk characterization used a weight-of-evidence approach and concluded that risk to mule deer behavior from the Apache overflight is uncertain, but that no risk to mule deer abundance and reproduction is expected.« less

Diets of mule deer within steppe vegetation of south central Washington. [Dietary preferences at three locations on the Hanford Reservation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uresk, D. W.; Uresk, V. A.

1978-01-01

The diets of mule deer (Odocoileus hemionus hemionus) on shrub-steppe rangeland of south central Washington were estimated by microhistological examination of fecal pellets. On rangelands, it is necessary to know the diets of herbivores and availability of forage plants to provide information for formulating better management programs for both plants and animals. The purpose of this study was to determine the dietary habits of mule deer at three locations on the 200 area plateau of the Hanford Reservation in south central Washington. The study area has not been grazed by livestock since 1943, but small mammals such as the black-tailedmore » hare (Lepus californicus) and ground squirrels (Citellus townsendi) do feed there.« less

The Starkey databases: spatial-environmental relations of North American elk, mule deer, and cattle at the Starkey Experimental Forest and Range in northeastern Oregon.

Treesearch

John G. Kie; Alan A. Ager; Norman J. Cimon; Michael J. Wisdom; Mary M. Rowland; Priscilla K. Coe; Scott L. Findholt; Bruce K. Johnson; Martin Vavra

2004-01-01

In the late 1980s, the Starkey Project was initiated to study interactions among North American elk (Cervus elaphus), mule deer (Odocoileus hemionus) and domestic cattle at Starkey Experimental Forest and Range (Starkey) in northeastern Oregon. As part of the Starkey Project, an automated radio telemetry system was developed to...

Beyond Carrots and Sticks: Toward a Transformative Model of Division I Athletics

ERIC Educational Resources Information Center

Clubb, Sandy Hatfield

2012-01-01

The old expression about the carrot and the stick, which refers to the application of reward and punishment to induce action, dates back to the days when pack mules were used for transportation. The mules would move toward carrots that dangled just ahead of them--and move all the faster because they feared drivers with sticks behind them. In 2012,…

FIRST AFRICAN CASE OF SPOROTRICHOSIS BEURMANI: TRANSMISSION OF SPOROTRICHOSIS FROM MULE TO MAN

DTIC Science & Technology

indefinite; its animal victims die of exhaustion. However, the classic iodine-iodide treatment for human sporotrichosis was found to be effective. This...particular sporotrichosis is of interest in human clinical study, since it can be transmitted from the animal to a healthy human. In fact, this first African case of human sporotrichosis was a case of mule-to-man infection.

Effects of cellulose levels on the apparent digestibility of feeds eaten by mule deer

Treesearch

Henry L. Short

1966-01-01

Three artificial diets that varied in cellulose content but were similar in protein and energy levels were fed to three mule deer according to a latin square design. Food intake for each deer, on each diet, during each feeding period was similar. Energy and dry matter digestion varied between diets (P < 0.05) and both digestible energy and digestible dry matter...

Individual and Population Level Resource Selection Patterns of Mountain Lions Preying on Mule Deer along an Urban-Wildland Gradient.

PubMed

Benson, John F; Sikich, Jeff A; Riley, Seth P D

2016-01-01

Understanding population and individual-level behavioral responses of large carnivores to human disturbance is important for conserving top predators in fragmented landscapes. However, previous research has not investigated resource selection at predation sites of mountain lions in highly urbanized areas. We quantified selection of natural and anthropogenic landscape features by mountain lions at sites where they consumed their primary prey, mule deer (Odocoileus hemionus), in and adjacent to urban, suburban, and rural areas in greater Los Angeles. We documented intersexual and individual-level variation in the environmental conditions present at mule deer feeding sites relative to their availability across home ranges. Males selected riparian woodlands and areas closer to water more than females, whereas females selected developed areas marginally more than males. Females fed on mule deer closer to developed areas and farther from riparian woodlands than expected based on the availability of these features across their home ranges. We suggest that mortality risk for females and their offspring associated with encounters with males may have influenced the different resource selection patterns between sexes. Males appeared to select mule deer feeding sites mainly in response to natural landscape features, while females may have made kills closer to developed areas in part because these are alternative sites where deer are abundant. Individual mountain lions of both sexes selected developed areas more strongly within home ranges where development occurred less frequently. Thus, areas near development may represent a trade-off for mountain lions such that they may benefit from foraging near development because of abundant prey, but as the landscape becomes highly urbanized these benefits may be outweighed by human disturbance.

Niche relationships within a guild of ungulate species in Yellowstone National Park, Wyoming, following release from artificial controls

USGS Publications Warehouse

Singer, Francis J.; Norland, Jack E.

1994-01-01

Niche relationships and diet overlaps were compared among elk (Cervus elaphus), bison (Bison bison), bighorn sheep (Ovis canadensis), mule deer (Odocoileus hemionus), and pronghorn antelope (Antilocapra americana) between 1967–1970 and 1986–1988, a period when total ungulate numbers nearly tripled on Yellowstone's northern range. Ungulate species ratios on Yellowstone's northern winter range during the latter period were 100 elk : 10 mule deer : 3 bison : 2 pronghorns : 1 bighorns. Elk numbers were positively correlated to bison, mule deer, and pronghorn numbers (r2 = 0.76, 0.97, and 0.48, respectively, P < 0.01). Few other changes in habitat use or habitat overlap occurred, and diets for only 2 of the 10 species pairs, elk-bighorn (Spearman's rank order coefficient (RHO) = 0.55, P < 0.05) and mule deer – pronghorn (RHO = 0.64, P < 0.05), were significantly associated with each other. Bison consumed more grass and fewer sedges, mule deer more fringed sage (Artemisia frigida) and more rabbit-brush (Chrysothamnus spp.), and bighorn sheep more grasses and fewer sedges, while pronghorns ate less saltsage (Atriplex nuttalli) but more big sagebrush (Artemisia tridentata) during 1986–1988 than during 1967–1970. Bison expanded their range and bison and bighorn sheep used a wider variety of habitats. We found little evidence of change in competitive interactions between ungulate species. A few diet and habitat overlaps increased, the opposite of the prediction from the competitive exclusion principle amongst species, suggesting that intraspecific competition was more important. Several explanations are proposed for the lack of changes in niche relationships during a period of near tripling in density of the ungulate guild.

Hair coat properties of donkeys, mules and horses in a temperate climate.

PubMed

Osthaus, B; Proops, L; Long, S; Bell, N; Hayday, K; Burden, F

2018-05-01

There are clear differences between donkeys and horses in their evolutionary history, physiology, behaviour and husbandry needs. Donkeys are often kept in climates that they are not adapted to and as such may suffer impaired welfare unless protection from the elements is provided. To compare some of the hair coat properties of donkeys, mules and horses living outside, throughout the year, in the temperate climate of the UK. Longitudinal study. Hair samples were taken from 42 animals: 18 donkeys (4 females, 14 males), 16 horses (6 females, 10 males) and eight mules (5 females, 3 males), in March, June, September and December. The weight, length and width of hair were measured, across the four seasons, as indicators of the hair coat insulation properties. Donkeys' hair coats do not significantly differ across the seasons. All three measurements of the insulation properties of the hair samples indicate that donkeys do not grow a winter coat and that their hair coat was significantly lighter, shorter and thinner than that of horses and mules in winter. In contrast, the hair coats of horses changed significantly between seasons, growing thicker in winter. The measurements cover only a limited range of features that contribute to the thermoregulation of an animal. Further research is needed to assess shelter preferences by behavioural measures, and absolute heat loss via thermoimaging. Donkeys, and to a lesser extent mules, appear not to be as adapted to colder, wet climates as horses, and may therefore require additional protection from the elements, such as access to a wind and waterproof shelter, in order for their welfare needs to be met. © 2017 The Authors. Equine Veterinary Journal published by John Wiley & Sons Ltd on behalf of EVJ Ltd.

Individual and Population Level Resource Selection Patterns of Mountain Lions Preying on Mule Deer along an Urban-Wildland Gradient

PubMed Central

Benson, John F.; Sikich, Jeff A.; Riley, Seth P. D.

2016-01-01

Understanding population and individual-level behavioral responses of large carnivores to human disturbance is important for conserving top predators in fragmented landscapes. However, previous research has not investigated resource selection at predation sites of mountain lions in highly urbanized areas. We quantified selection of natural and anthropogenic landscape features by mountain lions at sites where they consumed their primary prey, mule deer (Odocoileus hemionus), in and adjacent to urban, suburban, and rural areas in greater Los Angeles. We documented intersexual and individual-level variation in the environmental conditions present at mule deer feeding sites relative to their availability across home ranges. Males selected riparian woodlands and areas closer to water more than females, whereas females selected developed areas marginally more than males. Females fed on mule deer closer to developed areas and farther from riparian woodlands than expected based on the availability of these features across their home ranges. We suggest that mortality risk for females and their offspring associated with encounters with males may have influenced the different resource selection patterns between sexes. Males appeared to select mule deer feeding sites mainly in response to natural landscape features, while females may have made kills closer to developed areas in part because these are alternative sites where deer are abundant. Individual mountain lions of both sexes selected developed areas more strongly within home ranges where development occurred less frequently. Thus, areas near development may represent a trade-off for mountain lions such that they may benefit from foraging near development because of abundant prey, but as the landscape becomes highly urbanized these benefits may be outweighed by human disturbance. PMID:27411098

Walking on thin ice! Identifying methamphetamine "drug mules" on digital plain radiography.

PubMed

Abdul Rashid, S N; Mohamad Saini, S B; Abdul Hamid, S; Muhammad, S J; Mahmud, R; Thali, M J; Flach, P M

2014-04-01

The purpose of this study was to retrospectively evaluate the sensitivity, specificity and accuracy of identifying methamphetamine (MA) internal payloads in "drug mules" by plain abdominal digital radiography (DR). The study consisted of 35 individuals suspected of internal MA drug containers. A total of 59 supine digital radiographs were collected. An overall calculation regarding the diagnostic accuracy for all "drug mules" and a specific evaluation concerning the radiological appearance of drug packs as well as the rate of clearance and complications in correlation with the reader's experience were performed. The gold standard was the presence of secured drug packs in the faeces. There were 16 true-positive "drug mules" identified. DR of all drug carriers for Group 1 (forensic imaging experienced readers, n = 2) exhibited a sensitivity of 100%, a mean specificity of 76.3%, positive predictive value (PPV) of 78.5%, negative predictive value (NPV) of 100% and a mean accuracy 87.2%. Group 2 (inexperienced readers, n = 3) showed a lower sensitivity (93.7%), a mean specificity of 86%, a PPV of 86.5%, an NPV of 94.1% and a mean accuracy of 89.5%. The interrater agreement within Group 1 was 0.72 and within Group 2 averaged to 0.79, indicating a fair to very good agreement. DR is a valuable screening tool in cases of MA body packers with huge internal payloads being associated with a high diagnostic insecurity. Diagnostic insecurity on plain films may be overcome by low-dose CT as a cross-sectional imaging modality and addressed by improved radiological education in reporting drug carriers on imaging. Diagnostic signs (double-condom and halo signs) on digital plain radiography are specific in MA "drug mules", although DR is associated with high diagnostic insecurity and underreports the total internal payload.

Effect of feed consumption levels on growth performance and carcass composition during the force-feeding period in foie gras production of male Mule ducks.

PubMed

Wen, Z G; Jiang, Y; Tang, J; Xie, M; Yang, P L; Hou, S S

2016-09-01

In order to avoid excess feed consumption during the force-feeding period in foie gras production, a dose-response experiment with seven feed consumption levels (450, 540, 630, 720, 810, 900, 990 g/day per bird) was conducted to evaluate the effects of feed consumption levels on growth performance and carcass composition of male Mule ducks from 91 to 102 days of age. One-day-old Mule ducklings (sterile and artificial hybrid of male Albatre Muscovy duck and female Pekin duck were fed a two-phase commercial diets for ad libitum intake from hatching to 91 days of age, followed by graded feeding levels of a corn diet by force-feeding from 91 to 102 days of age. Fifty-six 91-day-old male Mule ducks with similar BW were randomly assigned to seven treatments, with eight birds per treatment. Birds were housed in individual pens. At 102 days of age, final BW was measured and BW gain and feed conversion ratio of ducks from each treatment were calculated from day 91 to 102, and then all ducks were slaughtered to evaluate the yields of skin with subcutaneous fat, abdominal fat, breast meat (including pectoralis major and pectoralis minor), leg meat (including thigh and drum stick), and liver. Significant differences in BW gain, total liver weight and liver relative weight were observed among the treatments (P<0.001). According to the broken-line regression analysis, the optimal feed consumption levels of male Mule ducks from 91 to 102 days of age for maximum BW gain, total liver weight and liver relative weight were 217, 227 and 216 g feed/kg BW0.75·per day, respectively.

Weather severity index on a mule deer winter range. [Odocoileus hemionus hemionus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leckenby, D.A.; Adams, A.W.

1986-05-01

Temperature, wind, and snow conditions predictably affect the nutrition, behavior, distribution, productivity, and mortality of free-ranging cattle and big game in winter. Indexing of data obtained with commonly available weather instruments to reflect episodes of positive and negative energy balances of free-ranging ruminants could aid scheduling of feeding programs and planning of cover-forage manipulations. Such a weather severity index was developed and tested over 11 winters. Plausible levels of stress and episodes of relative severity were depicted during winters when mule deer exhibited low, moderate, and high mortality. The index curves mirrored over-winter declines of fat reserves probably sustained bymore » mule deer. Lesser weather severity was predicted and measured in a western juniper woodland than in an adjacent rabbitbrush steppe community in southcentral Oregon. 32 references, 3 figures, 2 tables.« less

Design Description for Team-Based Execution of Autonomous Missions (TEAM), Spiral 1

DTIC Science & Technology

2008-11-18

TEAM), Spiral 1 Doc. #: Version: 1.0 Date: November 18, 2008 Page 12 of 39 Visualization Framework (WorldWind) Hibernate / Hibernate ...Spatial hibernate -properties XML Mapping WCS WFSWMS Enterprise Service Bus (Mule) Messaging, Data Transformation, Intelligent Routing Workflow Engine...government selected solutions. Neither these nor Mule® are deliverable, but the government may opt to use them if it so chooses. jBPM, java Business

Big sagebrush in pinyon-juniper woodlands: Using forest inventory and analysis data as a management tool for quantifying and monitoring mule deer habitat

Treesearch

Chris Witt; Paul L. Patterson

2011-01-01

We used Interior West Forest Inventory and Analysis (IW-FIA) data to identify conditions where pinyon-juniper woodlands provide security cover, thermal cover, and suitable amounts of big sagebrush (Artemisia tridentata spp.) forage to mule deer in Utah. Roughly one quarter of Utah's pinyon-juniper woodlands had a big sagebrush component in their understory....

Tagging studies of mule deer fawns on the Hanford Site, 1969 to 1977

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eberhardt, L.E.; Hedlund, J.D.; Rickard, W.H.

1979-10-01

From 1969 to 1977, 346 mule deer (Odocoileus hemionus) fawns were tagged and released on islands and shoreline habitat associated with the Columbia River on the Hanford Site in south-central Washington. The purpose was to determine the movement of mule deer along the Columbia River shoreline from the Hanford Site through tag recovery. Twenty-one tagged deer have been killed primarily by hunters near the Hanford Site or on areas of the Hanford Site open to public access. Movements of up to 113 km from Hanford have been documented. Although the Columbia River at Hanford is one of the largest andmore » most swift-flowing rivers in North America it is not an impassable barrier to mule deer. River islands are important and perhaps critical fawining habitat for the local deer herd. The selection of these islands by pregnant female deer is apparently influenced by predation, human access, and recreational use of islands. The number of fawns captured decreased during the latter years of the study (1974 to 1977). This is probably a reflection of an actual decrease in deer productivity, particularly along the upper stretch of the Columbia flowing through the Hanford Site. The reasons for this apparent decrease are unkown.« less

"Atypical" chronic wasting disease in PRNP genotype 225FF mule deer.

PubMed

Wolfe, Lisa L; Fox, Karen A; Miller, Michael W

2014-07-01

We compared mule deer (Odocoileus hemionus) of two different PRNP genotypes (225SS, 225FF) for susceptibility to chronic wasting disease (CWD) in the face of environmental exposure to infectivity. All three 225SS deer had immunohistochemistry (IHC)-positive tonsil biopsies by 710 days postexposure (dpe), developed classic clinical signs by 723-1,200 dpe, and showed gross and microscopic pathology, enzyme-linked immunosorbent assay (ELISA) results, and IHC staining typical of prion disease in mule deer. In contrast, although all three 225FF deer also became infected, the two individuals surviving >720 dpe had consistently negative biopsies, developed more-subtle clinical signs of CWD, and died 924 or 1,783 dpe. The 225FF deer were "suspect" by ELISA postmortem but showed negative or equivocal IHC staining of lymphoid tissues; both clinically affected 225FF deer had spongiform encephalopathy in the absence of IHC staining in the brain tissue. The experimental cases resembled three cases encountered among five additional captive 225FF deer that were not part of our experiment but also died from CWD. Aside from differences in clinical disease presentation and detection, 225FF mule deer also showed other, more-subtle, atypical traits that may help to explain the rarity of this genotype in natural populations, even in the presence of enzootic CWD.

2005 NDIA Combat Vehicles Conference. Volume 2- Thursday Presentations and Videos

DTIC Science & Technology

2005-09-22

Mounted Combat System MULE: (Countermine) MULE: (Transport) Class II Class III Class IV Armed Robotic Vehicle ARV RSTA ARV Assault FCS Recovery and...Vehicles – Infantry Carrier Vehicle (ICV) – Armed Robotic Vehicle - Assault (ARV (A)) – Recon & Surveillance Vehicle (RSV)  Training Ammo for AP & AB...Holtz and Mr. Dick Williams, Boeing Mr. Dean Vanderstelt, General Dynamics Land Systems ( GDLS ) Mr. Mike Zoltoski, TARDEC Mr. Peter DeMasi, Program

Suspected ivermectin toxicosis in a miniature mule foal causing blindness.

PubMed

Plummer, Caryn E; Kallberg, Maria E; Ollivier, Franck J; Brooks, Dennis E; Gelatt, Kirk N

2006-01-01

A 9-week-old miniature mule foal presented to the Veterinary Medical Teaching Hospital for acute blindness, ataxia, and depression following an overdose of an over-the-counter ivermectin-based de-worming medication. Ophthalmic examination and electrodiagnostic evaluation eliminated outer retinal abnormalities as the primary cause of the bilateral blindness, implicating instead a central neurologic effect of the drug. With symptomatic and supportive care, the foal recovered fully and regained its vision.

Ultrasonographic features of the mule embryo, fetus and fetal-placental unit.

PubMed

Paolucci, M; Palombi, C; Sylla, L; Stradaioli, G; Monaci, M

2012-01-15

The aim of this study was to establish baseline ultrasound data concerning the mule conceptus during gestation. Ten multiparous Trotter mares were artificially inseminated with chilled semen from an Amiatino jack donkey. Daily transrectal ultrasonography was carried out from the day of ovulation until Day 50 of gestation to determine the following: first detection of the embryonic vesicle (EV), mobility phase, EV diameter, day of EV fixation, changes in EV shape, date of yolk sac regression and embryo crown-rump length. Monthly ultrasonic assessments from Day 50 of gestation to term were carried out. These assessments included an evaluation of fetal well-being and the growth of the mule conceptus, which were monitored using the following variables: cardiac activity, fetal activity and presentation, fetal fluid echogenicity, combined thickness of the utero-placenta unit and fetal orbital and aortic diameter. Mule EV first detection was observed earlier (37% at Day 8) than that observed in the equine pregnancy. EV diameter at first detection was 4.6 ± 1.1 mm. At Day 10, 75% of EVs were detected. EV fixation occurred on Day 17.1 ± 1.1, with a mean EV diameter of 2.5 ± 0.2 cm. EV growth rate was 4.04 mm/day from Days 11 to 16, 0.4 mm/day from Days 16 to 28 and 1.78 mm/day from Days 28 to 45 of pregnancy. The embryo proper was first detected on Day 19.9 ± 1.9 (average length 2.4 ± 1.4 mm), and the embryonic heartbeat was first detected on Day 24 ± 2.4. The fetal carotid pulse was observed at six months of gestation and provided a good means by which to estimate fetal cardiac activity in advanced gestation. The fetal heart rate was recorded from Month 2 of gestation to term. The mean ± SD of the combined uteroplacental thickness was assessed at the cervical-placental junction and at the ventral abdomen in mares between Months 2 and 5 until term, respectively. An abnormal fetal-placental unit and fetal inactivity was observed in association with abortion. Mule-conceptus biometric measurements correlated significantly with the gestational age, and these data were used to predict an unusually large mule fetus, which might result in dystocia. In conclusion, we can assume that early diagnosis of pregnancy failure and assessment of fetal biophysical profile and growth charts could improve the chances of gestation completion in mule-pregnant mares. The early detection of mares at risk for an abnormal pregnancy or delivery may increase the success of prompt treatments, therefore preventing costly emergency procedures and allowing proper obstetrical and neonatal assistance. Copyright © 2012 Elsevier Inc. All rights reserved.

Lead in mule deer forage in Rocky Mountain National Park, Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harrison, P.D.; Dyer, M.I.

1984-01-01

Mule deer (Odocoileus hemionus) forage collected from roadsides in Rocky Mountain National Park, Colorado, contained lead (Pb) concentrations ranging from 0.8 to >50 ..mu..g/g. Concentrations were inversely correlated with distance from the roadway. Equations developed to estimate deer absorption of Pb from contaminated roadside vegetation indicate that deer in some age-classes need only to consume 1.4% of their daily intake of forage from roadsides before consuming excessive amounts of Pb.

Dysautonomia in a six-year-old mule in the United States.

PubMed

Wright, A; Beard, L; Bawa, B; Bras, J

2010-03-01

Equine dysautonomia, also known as equine grass sickness (EGS), is a well documented disease in several countries. To the authors' knowledge, EGS has not been reported previously in North America. This report describes EGS in a 6-year-old female mule in the USA. Failure initially to consider EGS resulted in a delayed diagnosis. EGS should be considered as a differential diagnosis and appropriate diagnostic tests performed in similar cases in North America.

Leg pairs as virtual wheels

NASA Astrophysics Data System (ADS)

Howe, Russel; Duttweiler, Mark; Khanlian, Luke; Setrakian, Mark

2005-05-01

We propose the use of virtual wheels as the starting point of a new vehicle design. Each virtual wheel incorporates a pair of simple legs that, by simulating the rotary motion and ground contact of a traditional wheel, combine many of the benefits of legged and wheeled motion. We describe the use of virtual wheels in the design of a robotic mule, presenting an analysis of the mule's mobility the results of our efforts to model and build such a device.

Food habits of pumas in northwestern Sonora, Mexico

USGS Publications Warehouse

Rosas-Rosas, O. C.; Valdez, R.; Bender, L.C.; Daniel, D.

2003-01-01

It is questionable whether food-habits studies of pumas conducted in the southwestern United States can be extrapolated to northwestern Mexico, because of differences in management, distribution, and abundance of wildlife. We determined food habits of pumas (Puma concolor) in the Sonoran Desert of northwestern Sonora, Mexico. Based on studies in the western United States, we hypothesized that desert mule deer (Odocoileus hemionus) were the major food source of pumas in Sonoran Desert habitats of Mexico. The study area supports populations of desert mule deer, white-tailed deer (Odocoileus virginianus), lagomorphs (Lepus spp. and Sylvilagus audubonii), collared peccary (Pecari tajacu), and the largest population (???300 individuals) of desert bighorn sheep (Ovis canadensis) in Sonora. Based on pugmark characteristics, we recorded 3 different adult resident pumas in approximately 90 km2. We analyzed 60 puma fecal samples collected September 1996-November 1998. Primary prey items based on frequency of occurrence and estimated biomass consumed were desert bighorn sheep (40% and 45%, respectively), lagomorphs (33%, 19%), deer (17%, 17%), and collared peccary (15%, 11%). The high percentage of desert bighorn sheep in puma diets may be due to high abundance relative to mule deer, which declined in number during our study. No differences were found in puma diets between seasons (??22=2.4526, P=0.2934). Fluctuations in mule deer populations in northwestern Sonora may influence prey selection by pumas.

Immobilization of mule deer with thiafentanil (A-3080) or thiafentanil plus xylazine.

PubMed

Wolfe, Lisa L; Lance, William R; Miller, Michael W

2004-04-01

We evaluated thiafentanil oxalate (A-3080) for the immobilization of mule deer (Odocoileus hemionus) under laboratory and field conditions. In a crossover experiment comparing recommended (0.1 mg/kg) and 2x recommended thiafentanil doses in captive deer, both produced rapid induction and immobilization. Mean induction was shorter (P = 0.013) for the 2x group (1.9 vs. 3 min); mean reversals for both groups were rapid (recommended = 0.9 min after naltrexone injection; 2x = 1 min) and did not differ (P = 0.29). Six free-ranging mule deer were immobilized with 7 mg thiafentanil and four with 10 mg; mean induction was 2.3 min for both groups (95% confidence interval [CI]: 7 mg, 1.2-3.4; 10 mg, 1.9-2.8), and mean reversal was <1 min for both groups. Of 165 free-ranging deer darted with various combinations of thiafentanil and xylazine, we successfully immobilized 148 (90%). Mean induction ranged from 2.1 to 4.9 min for different drug combinations. Reversals were not compared because naltrexone and yohimbine doses varied, but overall mean reversal was 1.9 min (95% CI, 1.7-2.1 min) after injection of naltrexone and yohimbine intravenously (i.v.); naltrexone:thiafentanil ratios ranging from 10:1 to 43:1 provided mean recoveries ranging from 1.5 to 2.3 min. All 25 deer fitted with radio collars were alive at 30 days postcapture. On the basis of overall reliability and effectiveness, drug volumes, and ease of handling drugged animals, we recommend using a combination of 10-12 mg thiafentanil (0.15-0.2 mg/kg) and 100 mg xylazine to immobilize mule deer; immobilization can be effectively reversed with 100 mg naltrexone or more and 15 mg yohimbine or more i.v. Where feasible, we also recommend the use of transmitter darts when immobilizing mule deer with opioids in order to maximize recovery of darted deer and to ensure that missed darts are found.

Re-evaluating neonatal-age models for ungulates: Does model choice affect survival estimates?

USGS Publications Warehouse

Grovenburg, Troy W.; Monteith, Kevin L.; Jacques, Christopher N.; Klaver, Robert W.; DePerno, Christopher S.; Brinkman, Todd J.; Monteith, Kyle B.; Gilbert, Sophie L.; Smith, Joshua B.; Bleich, Vernon C.; Swanson, Christopher C.; Jenks, Jonathan A.

2014-01-01

New-hoof growth is regarded as the most reliable metric for predicting age of newborn ungulates, but variation in estimated age among hoof-growth equations that have been developed may affect estimates of survival in staggered-entry models. We used known-age newborns to evaluate variation in age estimates among existing hoof-growth equations and to determine the consequences of that variation on survival estimates. During 2001–2009, we captured and radiocollared 174 newborn (≤24-hrs old) ungulates: 76 white-tailed deer (Odocoileus virginianus) in Minnesota and South Dakota, 61 mule deer (O. hemionus) in California, and 37 pronghorn (Antilocapra americana) in South Dakota. Estimated age of known-age newborns differed among hoof-growth models and varied by >15 days for white-tailed deer, >20 days for mule deer, and >10 days for pronghorn. Accuracy (i.e., the proportion of neonates assigned to the correct age) in aging newborns using published equations ranged from 0.0% to 39.4% in white-tailed deer, 0.0% to 3.3% in mule deer, and was 0.0% for pronghorns. Results of survival modeling indicated that variability in estimates of age-at-capture affected short-term estimates of survival (i.e., 30 days) for white-tailed deer and mule deer, and survival estimates over a longer time frame (i.e., 120 days) for mule deer. Conversely, survival estimates for pronghorn were not affected by estimates of age. Our analyses indicate that modeling survival in daily intervals is too fine a temporal scale when age-at-capture is unknown given the potential inaccuracies among equations used to estimate age of neonates. Instead, weekly survival intervals are more appropriate because most models accurately predicted ages within 1 week of the known age. Variation among results of neonatal-age models on short- and long-term estimates of survival for known-age young emphasizes the importance of selecting an appropriate hoof-growth equation and appropriately defining intervals (i.e., weekly versus daily) for estimating survival.

African horse sickness in Portugal: a successful eradication programme.

PubMed Central

Portas, M.; Boinas, F. S.; Oliveira E Sousa, J.; Rawlings, P.

1999-01-01

African horse sickness (AHS) was diagnosed for the first time in southern Portugal in autumn 1989, following outbreaks in Spain. AHS virus presence was confirmed by virus isolation and serotyping. An eradication campaign with four sanitary zones was set up by Central Veterinary Services in close collaboration with private organizations. Vaccination began on 6 October. In February 1990, vaccination was extended to all Portuguese equines (170000 animals). There were 137 outbreaks on 104 farms: 206 of the equidae present died (16%) or were slaughtered (14%); 81.5% were horses, 10.7% were donkeys and 7.8% were mules. Clinical AHS occurred more frequently in horses than donkeys and mules. In the vaccinated population, 82 animals (62.2% horses and 37.8% mules and donkeys), died or were slaughtered due to suspected or confirmed AHS. One year after ending vaccination, December 1991, Portugal was declared free of AHS. Cost of eradication was US$1955513 (US$11.5/Portuguese equine). PMID:10579455

Asynchronous vegetation phenology enhances winter body condition of a large mobile herbivore.

PubMed

Searle, Kate R; Rice, Mindy B; Anderson, Charles R; Bishop, Chad; Hobbs, N T

2015-10-01

Understanding how spatial and temporal heterogeneity influence ecological processes forms a central challenge in ecology. Individual responses to heterogeneity shape population dynamics, therefore understanding these responses is central to sustainable population management. Emerging evidence has shown that herbivores track heterogeneity in nutritional quality of vegetation by responding to phenological differences in plants. We quantified the benefits mule deer (Odocoileus hemionus) accrue from accessing habitats with asynchronous plant phenology in northwest Colorado over 3 years. Our analysis examined both the direct physiological and indirect environmental effects of weather and vegetation phenology on mule deer winter body condition. We identified several important effects of annual weather patterns and topographical variables on vegetation phenology in the home ranges of mule deer. Crucially, temporal patterns of vegetation phenology were linked with differences in body condition, with deer tending to show poorer body condition in areas with less asynchronous vegetation green-up and later vegetation onset. The direct physiological effect of previous winter precipitation on mule deer body condition was much less important than the indirect effect mediated by vegetation phenology. Additionally, the influence of vegetation phenology on body fat was much stronger than that of overall vegetation productivity. In summary, changing annual weather patterns, particularly in relation to seasonal precipitation, have the potential to alter body condition of this important ungulate species during the critical winter period. This finding highlights the importance of maintaining large contiguous areas of spatially and temporally variable resources to allow animals to compensate behaviourally for changing climate-driven resource patterns.

Neonatal isoerythrolysis in horse foals and a mule foal: 18 cases (1988-2003).

PubMed

Boyle, Ashley G; Magdesian, K Gary; Ruby, Rebecca E

2005-10-15

To assess data regarding clinical features, clinicopathologic and blood gas variables, and outcome from horse and mule foals with confirmed neonatal isoerythrolysis (NI). Retrospective case series. 17 horse and 1 mule foals. Medical records of foals (< 14 days old) with NI were reviewed. Information collected included signalment; clinical examination findings; results of hematologic, serum and plasma biochemical, and venous blood gas analyses and urinalysis; treatments; and outcome. Data from 17 horse foals and 1 mule foal with NI (mean age, 71 hours) were evaluated. Many foals had high serum indirect and direct bilirubin concentrations and sorbitol dehydrogenase activity. Whole blood immunoglobulin concentrations were < 400 mg/dL in 4 of 15 foals. Fresh whole blood transfusions were administered to 10 of 18 foals. Among the blood factors implicated in 11 foals, one (Dg) had not previously been associated with NI. Of 10 foals that received blood transfusions, 7 had significant improvements in Hct and hemoglobin concentration and 2 had significant improvements in central venous oxygen tension. Fifteen foals survived to discharge. Data suggest that blood factor Dg may be associated with NI in foals. Liver disease may be concurrent with NI in foals, and NI can develop in foals with inadequate passive transfer of colostral antibodies. Whole blood transfusions were successful at increasing oxygen-carrying capacity and improving peripheral tissue oxygenation in NI-affected foals. With appropriate treatment, the prognosis for foals with NI is good.

Comparative cardiopulmonary effects of carfentanil-xylazine and medetomidine-ketamine used for immobilization of mule deer and mule deer/white-tailed deer hybrids.

PubMed Central

Caulkett, N A; Cribb, P H; Haigh, J C

2000-01-01

Three mule deer and 4 mule deer/white-tailed deer hybrids were immobilized in a crossover study with carfentanil (10 microg/kg) + xylazine (0.3 mg/kg) (CX), and medetomidine (100 microg/kg) + ketamine (2.5 mg/kg) (MK). The deer were maintained in left lateral recumbency for 1 h with each combination. Deer were immobilized with MK in 230+/-68 s (mean +/- SD) and with CX in 282+/-83 seconds. Systolic, mean and diastolic arterial pressure were significantly higher with MK. Heart rate, PaO2, PaCO2, pH, and base excess were not significantly different between treatments. Base excess and pH increased significantly over time with both treatments. Both treatments produced hypoventilation (PaCO2 > 50 mm Hg) and hypoxemia (PaO2 < 60 mm Hg). PaO2 increased significantly over time with CX. Body temperature was significantly (P<0.05) higher with CX compared to MK. Ventricular premature contractions, atrial premature contractions, and a junctional escape rhythm were noted during CX immobilization. No arrhythmias were noted during MK immobilization. Quality of immobilization was superior with MK, with no observed movement present for the 60 min of immobilization. Movement of the head and limbs occurred in 4 animals immobilized with CX. The major complication observed with both of these treatments was hypoxemia, and supplemental inspired oxygen is recommended during immobilization. Hyperthermia can further complicate immobilization with CX, reinforcing the need for supplemental oxygen. PMID:10680659

Species-wide phylogeography of North American mule deer (Odocoileus hemionus): cryptic glacial refugia and postglacial recolonization.

PubMed

Latch, Emily K; Heffelfinger, James R; Fike, Jennifer A; Rhodes, Olin E

2009-04-01

Quaternary climatic oscillations greatly influenced the present-day population genetic structure of animals and plants. For species with high dispersal and reproductive potential, phylogeographic patterns resulting from historical processes can be cryptic, overshadowed by contemporary processes. Here we report a study of the phylogeography of Odocoileus hemionus, a large, vagile ungulate common throughout western North America. We examined sequence variation of mitochondrial DNA (control region and cytochrome b) within and among 70 natural populations across the entire range of the species. Among the 1766 individual animals surveyed, we recovered 496 haplotypes. Although fine-scale phylogenetic structure was weakly resolved using phylogenetic methods, network analysis clearly revealed the presence of 12 distinct haplogroups. The spatial distribution of haplogroups showed a strong genetic discontinuity between the two morphological types of O. hemionus, mule deer and black-tailed deer, east and west of the Cascade Mountains in the Pacific Northwest. Within the mule deer lineage, we identified several haplogroups that expanded before or during the Last Glacial Maximum, suggesting that mule deer persisted in multiple refugia south of the ice sheets. Patterns of genetic diversity within the black-tailed deer lineage suggest a single refugium along the Pacific Northwest coast, and refute the hypothesis that black-tailed deer persisted in one or more northern refugia. Our data suggest that black-tailed deer recolonized areas in accordance with the pattern of glacial retreat, with initial recolonization northward along a coastal route and secondary recolonization inland.

A robust nonlinear skid-steering control design applied to the MULE (6x6) unmanned ground vehicle

NASA Astrophysics Data System (ADS)

Kaloust, Joseph

2006-05-01

The paper presents a robust nonlinear skid-steering control design concept. The control concept is based on the recursive/backstepping control design technique and is capable of compensating for uncertainties associated with sensor noise measurements and/or system dynamic state uncertainties. The objective of this control design is to demonstrate the performance of the nonlinear controller under uncertainty associate with road traction (rough off-road and on-road terrain). The MULE vehicle is used in the simulation modeling and results.

Experimental contagious ecthyma in mule deer, white-tailed deer, pronghorn and wapiti.

PubMed

Lance, W R; Hibler, C P; DeMartini, J

1983-07-01

Hand-reared mule deer fawns (Odocoileus hemionus), white-tailed deer fawns (Odocoileus virginianus), pronghorn fawns (Antilocapra americana) and wapiti calves (Cervus elaphus nelsoni) were exposed to contagious ecthyma lesion material obtained from Rocky Mountain bighorn sheep (Ovis canadensis canadensis) to determine the susceptibility and pathogenesis in these species. All four species developed mucocutaneous proliferative lesions of the oral cavity, grossly and histologically compatible with contagious ecthyma. The limited clinical responses to the virus indicated that contagious ecthyma would not seriously impact free-ranging individuals.

What You See Depends on Your Point of View: Comparison of Greenness Indices Across Spatial and Temporal Scales and What That Means for Mule Deer Migration and Fitness

NASA Astrophysics Data System (ADS)

Miller, B. W.; Chong, G.; Steltzer, H.; Aikens, E.; Morisette, J. T.; Talbert, C.; Talbert, M.; Shory, R.; Krienert, J. M.; Gurganus, D.

2015-12-01

Climate change models for the north­ern Rocky Mountains predict warming and changes in water availability that may alter vegetation. Changes to vegetation may include timing of plant life-history events, or phenology, such as green-up, flower­ing, and senescence. These changes could make forage available earlier in the growing season, but shifts in phenol­ogy may also result in earlier senescence (die-off or dormancy) and reduced overall production. Greenness indices such as the normalized difference vegetation index (NDVI) are regularly used to quantify greenness over large areas using remotely sensed reflectance data. The timing and scale of current satellite data, however, may be insufficient to capture fine-scale differences in phenology that are important indicators of habitat quality. The Wyoming Range Mule Deer herd is one of the largest in the west but it declined precipitously in the early 1990s and has not recovered. Accurate measurement of greenness over space and time would allow managers to better understand the role of plant phenology and productivity in mule deer population dynamics, for example. To connect spatial and temporal patterns of plant productivity with habitat quality, we compare greenness patterns (MODIS data) with migratory mule deer movement (GPS collars). Sagebrush systems provide winter habitat for mule deer. To understand sagebrush phenology as an indicator of productivity, we constructed NDVI time series and compared dates of phenological stages and magnitudes of greenness from three perspectives: at-surface/species-specific (mantis sensors: downward looking, <1m above vegetation); near surface/site-specific (PhenoCam: oblique, 2m); and satellite/landscape-scale (varied platforms). Greenness indices from these sensors contribute unique insights to understanding vegetation phenology, snow cover and reflectance. Understanding phenology and productivity at multiple scales can help guide resource management decisions related to habitat quality, and evaluate what remotely sensed phenology measurements mean on the ground. Monitoring changes in phenology and productivity over the long-term can provide insight into ecosystem responses to climate change.

Influence of grand-mother diet on offspring performances through the male line in Muscovy duck.

PubMed

Brun, Jean-Michel; Bernadet, Marie-Dominique; Cornuez, Alexis; Leroux, Sophie; Bodin, Loys; Basso, Benjamin; Davail, Stéphane; Jaglin, Mathilde; Lessire, Michel; Martin, Xavier; Sellier, Nadine; Morisson, Mireille; Pitel, Frédérique

2015-12-21

In mammals, multigenerational environmental effects have been documented by either epidemiological studies in human or animal experiments in rodents. Whether such phenomena also occur in birds for more than one generation is still an open question. The objective of this study was to investigate if a methionine deficiency experienced by a mother (G0) could affect her grand-offspring phenotypes (G2 hybrid mule ducks and G2 purebred Muscovy ducks), through their Muscovy sons (G1). Muscovy drakes are used for the production of mule ducks, which are sterile offspring of female common duck (Anas platyrhynchos) and Muscovy drakes (Cairina moschata). In France, mule ducks are bred mainly for the production of "foie gras", which stems from hepatic steatosis under two weeks of force-feeding (FF). Two groups of female Muscovy ducks received either a methionine deficient diet or a control diet. Their sons were mated to Muscovy or to common duck females to produce Muscovy or Mule ducks, respectively. Several traits were measured in the G2 progenies, concerning growth, feed efficiency during FF, body composition after FF, and quality of foie gras and magret. In the G2 mule duck progeny, grand-maternal methionine deficiency (GMMD) decreased 4, 8, and 12 week body weights but increased weight gain and feed efficiency during FF, and abdominal fat weight. The plasmatic glucose and triglyceride contents at the end of FF were higher in the methionine deficient group. In the G2 purebred Muscovy progeny, GMMD tended to decrease 4 week body weight in both sexes, and decreased weight gain between the ages of 4 and 12 weeks, 12 week body weight, and body weight at the end of FF in male offspring only. GMMD tended to increase liver weight and increased the carcass proportion of liver in both sexes. Altogether, these results show that the mother's diet is able to affect traits linked to growth and to lipid metabolism in the offspring of her sons, in Muscovy ducks. Whether this transmission through the father of information induced in the grand-mother by the environment is epigenetic remains to be demonstrated.

Development of a duplex semi-nested PCR assay for detection of classical goose parvovirus and novel goose parvovirus-related virus in sick or dead ducks with short beak and dwarfism syndrome.

PubMed

Li, Pengfei; Zhang, Ruihua; Chen, Junhao; Sun, Dapeng; Lan, Jingjing; Lin, Shaoli; Song, Shasha; Xie, Zhijing; Jiang, Shijin

2017-11-01

Duck short beak and dwarfism syndrome (SBDS) is an emerging infectious disease caused by a novel goose parvovirus-related virus (NGPV) in China. Until now, it remains uncertain whether the Cherry Valley ducks and mule ducks with SBDS are co-infected with classical goose parvovirus (GPV) and NGPV. In this study, a duplex semi-nested PCR assay with high specificity and sensitivity was developed for detection of the two viruses. Using the duplex PCR assay, NGPV was tested positive in all the 15 duck flocks with SBDS, whereas classical GPV was not detected in all the 133 sick and dead ducks collected from East China. A total of 87 (91.58%) Cherry Valley ducks aged from 5 to 18days and 35 (92.11%) mule ducks aged from 17 to 25days were detected positive for NGPV. In the NGPV-positive ducks, the virus detection rates were 81.97% to 8.20% in heart, liver, spleen, lung, kidney, pancreas, bile, thymus, bursa of Fabricius, and brain. The results indicated that NGPV was prevalent in the duck flocks of East China, whereas classical GPV was not detected in Cherry Valley ducks and mule ducks with SBDS. NGPV has extensive tissue tropism in Cherry Valley duck and mule duck, which could invade both the central and peripheral immune organs and break through the blood-brain barrier of ducks. Copyright © 2017 Elsevier B.V. All rights reserved.

Probiotics Strains Modulate Gut Microbiota and Lipid Metabolism in Mule Ducks

PubMed Central

Even, Maxime; Davail, Stéphane; Rey, Mikael; Tavernier, Annabelle; Houssier, Marianne; Bernadet, Marie Dominique; Gontier, Karine; Pascal, Géraldine; Ricaud, Karine

2018-01-01

Background: Livestock production should respond to societal, environmental and economic changes. Since 2006 and the ban on antibiotics as growth factors in European Union, the use of probiotics has become widespread and has demonstrated the effect of intestinal microbiota on the performance of farm animals. Objective: The aim of this study was to investigate the effect of supplementation with Lactobacillus salivarius (as a probiotics strain or combined with other strains) on zootechnical performance, metabolic and immune gene expression and intestinal microbiota diversity in mule ducks using high-throughput sequencing and real-time PCR. Method: The mule ducks were reared for 79 days and overfed for 12 days with or without probiotics. Samples were collected at 14 (starting period) and 91 days (end of overfeeding period), 3 hours post feeding. Results: Irrespective of digestive content, age, level of feed intake or supplementation with probiotics, Firmicutes, Proteobacteria and Bacteroidetes were the dominant phyla in the bacterial community in mule ducks. At 14 days, both the ileal and cecal samples were dominated by Firmicutes (in particular the Clostridiales order). Overfeeding induced a shift between Clostridiales and Lactobacillales in the ileal samples whereas in the cecal samples, the relative abundance of Firmicutes decreased. Overfeeding also induced hepatic over-expression of Fatty Acid Synthase (FAS) and of the lipid transporter gene Fatty Acid Binding Protein 4 (FABP4). This increase in lipid metabolism genes is associated with a decrease in inflammatory response. Conclusion: Finally, probiotic supplementation had only a slight impact on gene expression and microbiota diversity, both at 14 days and after overfeeding. PMID:29755604

Probiotics Strains Modulate Gut Microbiota and Lipid Metabolism in Mule Ducks.

PubMed

Even, Maxime; Davail, Stéphane; Rey, Mikael; Tavernier, Annabelle; Houssier, Marianne; Bernadet, Marie Dominique; Gontier, Karine; Pascal, Géraldine; Ricaud, Karine

2018-01-01

Livestock production should respond to societal, environmental and economic changes. Since 2006 and the ban on antibiotics as growth factors in European Union, the use of probiotics has become widespread and has demonstrated the effect of intestinal microbiota on the performance of farm animals. The aim of this study was to investigate the effect of supplementation with Lactobacillus salivarius (as a probiotics strain or combined with other strains) on zootechnical performance, metabolic and immune gene expression and intestinal microbiota diversity in mule ducks using high-throughput sequencing and real-time PCR. The mule ducks were reared for 79 days and overfed for 12 days with or without probiotics. Samples were collected at 14 (starting period) and 91 days (end of overfeeding period), 3 hours post feeding. Irrespective of digestive content, age, level of feed intake or supplementation with probiotics, Firmicutes , Proteobacteria and Bacteroidetes were the dominant phyla in the bacterial community in mule ducks. At 14 days, both the ileal and cecal samples were dominated by Firmicutes (in particular the Clostridiales order). Overfeeding induced a shift between Clostridiales and Lactobacillales in the ileal samples whereas in the cecal samples, the relative abundance of Firmicutes decreased. Overfeeding also induced hepatic over-expression of Fatty Acid Synthase ( FAS ) and of the lipid transporter gene Fatty Acid Binding Protein 4 ( FABP4 ). This increase in lipid metabolism genes is associated with a decrease in inflammatory response. Finally, probiotic supplementation had only a slight impact on gene expression and microbiota diversity, both at 14 days and after overfeeding.

Comparison of helicopter and ground surveys for North American elk Cervus elaphus and mule deer Odocoileus hemionus population composition

USGS Publications Warehouse

Bender, L.C.; Myers, W.L.; Gould, W.R.

2003-01-01

Both ground and helicopter surveys are commonly used to collect sex and age composition data for ungulates. Little attention has been paid, however, to whether data collected by each technique are similar. We compared helicopter and ground composition data for both elk Cervus elaphus and mule deer Odocoileus hemionus across a variety of habitats in the state of Washington, USA. We found that ground and helicopter counts differed (P's < 0.002) consistently in male age structure estimates for elk, and that the two survey methods differed in estimates of adult sex ratios for mule deer (P = 0.023). Counts from helicopters provided larger sample sizes, tended to be more consistent annually in their results, and were corroborated by other demographic studies of the test populations. We conclude that helicopter and ground surveys differ for male age structure and perhaps male:female ratios, but are similar for young:female ratios. Managers should maintain a standardized technique using the same survey vehicle for trend analysis of composition data.

Silicification of holocene soils in northern Monitor Valley, Nevada

NASA Astrophysics Data System (ADS)

Chadwick, O. A.; Hendricks, D. M.; Nettleton, W. D.

1989-02-01

Chemical, physical, and microscopic data for three soils in the northern Monitor Valley are analyzed. The soils ranked in order of increasing age are: Mule, Rotinom, and Nayped. The procedures and techniques used to obtain and study that data are described. It is observed that: (1) redistribution of carbonate is detectable in all soils; (2) clay illuviation is insignificant in the Mule soil, weak but identifiable in the Rotinom soil, and significant in the Nayped soil; and (3) the maximum sodium adsorption ratio (SAR) and electrical conductivity (EC) for the Mule soil is between 64-89 cm, for the Rotinom soil the values are below 100 cm, and for Nayped the maximum SAR values range from 51-117 cm and maximum EC values are between 117-152 cm. The relationship between volcanic glass weathering and the amount of silica cementation in the soils is studied. It is noted that silicification of Monitor Valley holocene soils is due to there being enough moisture to release silica from volcanic glass, but not enough to leach the weathering products from the profile.

Thermal Analysis of Solid Fuels in an Inert Atmosphere

NASA Astrophysics Data System (ADS)

Kijo-Kleczkowska, Agnieszka; Szumera, Magdalena; Środa, Katarzyna

2017-12-01

The paper takes the analysis of thermal studies of different types of fuels. It allowed diversification of fuels depending on their composition and origin. Consideration of coal, biomass and waste (coal mule, sewage sludge) as fuel is nowadays an important aspect of energy in our country. It should be emphasized that Poland power engineering is based up to 95% on coal - the primary fuel. Mining industry, forced to deliver power engineering more and better fuel, must however, use a deeper cleaning of coal. This results in a continuous increase waste in the form of mule flotation. The best method of disposing these mule is combustion and co-combustion with other fuels. On the other hand, commonly increasing awareness state of the environment and the need to reduce CO2 emissions energy industry have committed to implement alternative solutions in order to gain power, through, i.a.: development technologies use of biomass, which is one of the most promising renewable energy sources in Poland. The paper presents the results of research TG-DTA fuels made in an inert atmosphere.

AGE AND REPEATED BIOPSY INFLUENCE ANTEMORTEM PRP(CWD) TESTING IN MULE DEER (ODOCOILEUS HEMIONUS) IN COLORADO, USA.

PubMed

Geremia, Chris; Hoeting, Jennifer A; Wolfe, Lisa L; Galloway, Nathan L; Antolin, Michael F; Spraker, Terry R; Miller, Michael W; Hobbs, N Thompson

2015-10-01

Biopsy of rectal mucosa-associated lymphoid tissue provides a useful, but imperfect, live-animal test for chronic wasting disease (CWD) in mule deer (Odocoileus hemionus). It is difficult and expensive to complete these tests on free-ranging animals, and wildlife health managers will benefit from methods that can accommodate test results of varying quality. To this end, we developed a hierarchical Bayesian model to estimate the probability that an individual is infected based on test results. Our model was estimated with the use of data on 210 adult female mule deer repeatedly tested during 2010-14. The ability to identify infected individuals correctly declined with age and may have been influenced by repeated biopsy. Fewer isolated lymphoid follicles (where PrP(CWD) accumulates) were obtained in biopsies of older deer and the proportion of follicles showing PrP(CWD) was reduced. A deer's genotype in the prion gene (PRNP) also influenced detection. At least five follicles were needed in a biopsy to assure a 95% accurate test in PRNP genotype 225SS deer.

Hungry Horse Dam Wildlife Habitat Enhancement Project: Long-Term Habitat Management Plan, Elk and Mule Deer Winter Range Enhancement, Firefighter Mountain and Spotted Bear Winter Ranges.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Casey, Daniel; Malta, Patrick

1990-06-01

Project goals are to rehabilitate 1120 acres of big game (elk and mule deer, Odocoileus hemionus) winter range on the Hungry Horse and Spotted Bear Districts of Flathead National Forest lands adjacent to Hungry Horse Reservoir. This project represents the initial phase of implementation toward the mitigation goal. A minimum of 547 acres Trust-funded enhancements are called for in this plan. The remainder are part of the typical Forest Service management activities for the project area. Monitor and evaluate the effects of project implementation on the big game forage base and elk and mule deer populations in the project area.more » Monitor enhancement success to determine effective acreage to be credited against mitigation goal. Additional enhancement acreage will be selected elsewhere in the Flathead Forest or other lands adjacent'' to the reservoir based on progress toward the mitigation goal as determined through monitoring. The Wildlife Mitigation Trust Fund Advisory Committee will serve to guide decisions regarding future enhancement efforts. 7 refs.« less

Silicification of holocene soils in northern Monitor Valley, Nevada

NASA Technical Reports Server (NTRS)

Chadwick, O. A.; Hendricks, D. M.; Nettleton, W. D.

1989-01-01

Chemical, physical, and microscopic data for three soils in the northern Monitor Valley are analyzed. The soils ranked in order of increasing age are: Mule, Rotinom, and Nayped. The procedures and techniques used to obtain and study that data are described. It is observed that: (1) redistribution of carbonate is detectable in all soils; (2) clay illuviation is insignificant in the Mule soil, weak but identifiable in the Rotinom soil, and significant in the Nayped soil; and (3) the maximum sodium adsorption ratio (SAR) and electrical conductivity (EC) for the Mule soil is between 64-89 cm, for the Rotinom soil the values are below 100 cm, and for Nayped the maximum SAR values range from 51-117 cm and maximum EC values are between 117-152 cm. The relationship between volcanic glass weathering and the amount of silica cementation in the soils is studied. It is noted that silicification of Monitor Valley holocene soils is due to there being enough moisture to release silica from volcanic glass, but not enough to leach the weathering products from the profile.

Kootenai River Wildlife Habitat Enhancement Project : Long-term Bighorn Sheep/Mule Deer Winter and Spring Habitat Improvement Project : Wildlife Mitigation Project, Libby Dam, Montana : Management Plan.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yde, Chis

1990-06-01

The Libby hydroelectric project, located on the Kootenai River in northwestern Montana, resulted in several impacts to the wildlife communities which occupied the habitats inundated by Lake Koocanusa. Montana Department of Fish, Wildlife and Parks, in cooperation with the other management agencies, developed an impact assessment and a wildlife and wildlife habitat mitigation plan for the Libby hydroelectric facility. In response to the mitigation plan, Bonneville Power Administration funded a cooperative project between the Kootenai National Forest and Montana Department of Fish, Wildlife and Parks to develop a long-term habitat enhancement plan for the bighorn sheep and mule deer wintermore » and spring ranges adjacent to Lake Koocanusa. The project goal is to rehabilitate 3372 acres of bighorn sheep and 16,321 acres of mule deer winter and spring ranges on Kootenai National Forest lands adjacent to Lake Koocanusa and to monitor and evaluate the effects of implementing this habitat enhancement work. 2 refs.« less

Mountain lions prey selectively on prion-infected mule deer

PubMed Central

Krumm, Caroline E.; Conner, Mary M.; Hobbs, N. Thompson; Hunter, Don O.; Miller, Michael W.

2010-01-01

The possibility that predators choose prey selectively based on age or condition has been suggested but rarely tested. We examined whether mountain lions (Puma concolor) selectively prey upon mule deer (Odocoileus hemionus) infected with chronic wasting disease, a prion disease. We located kill sites of mountain lions in the northern Front Range of Colorado, USA, and compared disease prevalence among lion-killed adult (≥2 years old) deer with prevalence among sympatric deer taken by hunters in the vicinity of kill sites. Hunter-killed female deer were less likely to be infected than males (odds ratios (OR) = 0.2, 95% confidence intervals (CI) = 0.1–0.6; p = 0.015). However, both female (OR = 8.5, 95% CI = 2.3–30.9) and male deer (OR = 3.2, 95% CI = 1–10) killed by a mountain lion were more likely to be infected than same-sex deer killed in the vicinity by a hunter (p < 0.001), suggesting that mountain lions in this area actively selected prion-infected individuals when targeting adult mule deer as prey items. PMID:19864271

KSC-2009-2704

NASA Image and Video Library

2009-04-16

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Multi-Use Lightweight Equipment, or MULE, carrier is lifted from its workstand to move it to the payload canister. The MULE contains hardware for the STS-125 mission to service NASA's Hubble Space Telescope. Atlantis' 11-day flight is targeted for launch May 12. The mission will include five spacewalks in which astronauts will refurbish and upgrade the telescope with state-of-the-art science instruments. As a result, Hubble's capabilities will be expanded and its operational lifespan extended through at least 2014. Photo credit: NASA/Tim Jacobs

KSC-2009-2703

NASA Image and Video Library

2009-04-16

CAPE CANAVERAL, Fla. – In the Payload Hazardous Servicing Facility at NASA's Kennedy Space Center in Florida, the Multi-Use Lightweight Equipment, or MULE, carrier is being lifted from its workstand to move it to the payload canister. The MULE contains hardware for the STS-125 mission to service NASA's Hubble Space Telescope. Atlantis' 11-day flight is targeted for launch May 12. The mission will include five spacewalks in which astronauts will refurbish and upgrade the telescope with state-of-the-art science instruments. As a result, Hubble's capabilities will be expanded and its operational lifespan extended through at least 2014. Photo credit: NASA/Tim Jacobs

KSC-08pd2640

NASA Image and Video Library

2008-09-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility at NASA’s Kennedy Space Center, the Multi-Use Logistic Equipment, or MULE, carrier is lowered into the payload canister. It is being placed next to the Flight Support System carrier already in the canister. The MULE is one of four associated with the STS-125 mission to service the Hubble Space Telescope. It will be installed in the payload canister for transfer to Launch Pad 39A. At the pad, all the carriers will be loaded into space shuttle Atlantis’ payload bay. Launch of Atlantis is targeted for Oct. 10. Photo credit: NASA/Jack Pfaller

KSC-08pd2639

NASA Image and Video Library

2008-09-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility at NASA’s Kennedy Space Center, the Multi-Use Logistic Equipment, or MULE, carrier is lowered toward the payload canister. It will be placed next to the Flight Support System carrier already in place. The MULE is one of four associated with the STS-125 mission to service the Hubble Space Telescope. It will be installed in the payload canister for transfer to Launch Pad 39A. At the pad, all the carriers will be loaded into space shuttle Atlantis’ payload bay. Launch of Atlantis is targeted for Oct. 10. Photo credit: NASA/Jack Pfaller

Quantifying Vertical Exhumation in Intracontinental Strike-Slip Faults: the Garlock fault zone, southern California

NASA Astrophysics Data System (ADS)

Chinn, L.; Blythe, A. E.; Fendick, A.

2012-12-01

New apatite fission-track ages show varying rates of vertical exhumation at the eastern terminus of the Garlock fault zone. The Garlock fault zone is a 260 km long east-northeast striking strike-slip fault with as much as 64 km of sinistral offset. The Garlock fault zone terminates in the east in the Avawatz Mountains, at the intersection with the dextral Southern Death Valley fault zone. Although motion along the Garlock fault west of the Avawatz Mountains is considered purely strike-slip, uplift and exhumation of bedrock in the Avawatz Mountains south of the Garlock fault, as recently as 5 Ma, indicates that transpression plays an important role at this location and is perhaps related to a restricting bend as the fault wraps around and terminates southeastward along the Avawatz Mountains. In this study we complement extant thermochronometric ages from within the Avawatz core with new low temperature fission-track ages from samples collected within the adjacent Garlock and Southern Death Valley fault zones. These thermochronometric data indicate that vertical exhumation rates vary within the fault zone. Two Miocene ages (10.2 (+5.0/-3.4) Ma, 9.0 (+2.2/-1.8) Ma) indicate at least ~3.3 km of vertical exhumation at ~0.35 mm/yr, assuming a 30°C/km geothermal gradient, along a 2 km transect parallel and adjacent to the Mule Spring fault. An older Eocene age (42.9 (+8.7/-7.3) Ma) indicates ~3.3 km of vertical exhumation at ~0.08 mm/yr. These results are consistent with published exhumation rates of 0.35 mm/yr between ~7 and ~4 Ma and 0.13 mm/yr between ~15 and ~9 Ma, as determined by apatite fission-track and U-Th/He thermochronometry in the hanging-wall of the Mule Spring fault. Similar exhumation rates on both sides of the Mule Spring fault support three separate models: 1) Thrusting is no longer active along the Mule Spring fault, 2) Faulting is dominantly strike-slip at the sample locations, or 3) Miocene-present uplift and exhumation is below detection levels using apatite fission-track thermochronometry. In model #1 slip on the Mule Spring fault may have propagated towards the range front, and may be responsible for the fault-propagation-folding currently observed along the northern branch of the Southern Death Valley fault zone. Model #2 may serve to determine where faulting has historically included a component of thrust faulting to the east of sample locations. Model #3 would further determine total offset along the Mule Spring fault from Miocene-present. Anticipated fission-track and U-Th/He data will help distinguish between these alternative models.

Prevalence of equine herpesvirus-1 and equine herpesvirus-4 infections in equidae species in Turkey as determined by ELISA and multiplex nested PCR.

PubMed

Ataseven, Veysel S; Dağalp, Seval B; Güzel, Murat; Başaran, Zeynep; Tan, Mehmet T; Geraghty, Bob

2009-04-01

In this report we examined the presence of specific antibodies against equine herpesvirus type 1 (EHV-1), and equine herpesvirus type 4 (EHV-4) in several equidae, including mules, donkeys, horses. The presence of EHV-1 and EHV-4 in respiratory diseases of equids, and ability of multiplex nested polymerase chain reaction (PCR) screening in simultaneous diagnosis of horses acutely infected by EHV-1 and EHV-4 were also investigated. Sera from 504 horses, mules and donkeys sampled were tested for the presence of EHV-1 and EHV-4 specific antibodies. Blood samples taken from 21 symptomatic horses and nasal swabs taken from 40 symptomatic horses were tested for the presence of EHV-1 and EHV-4 by a multiplex nested PCR. A total of 14.3% (3/21) of buffy coat samples and 32.5% (13/40) nasal swab samples were found to contain EHV-1 DNA, while 19% (4/21) buffy coat samples and 22.5% (9/40) nasal swab samples were found to be positive for EHV-4 DNA. By species, 14.5% of horses, 37.2% of mules and 24.2% of donkeys tested were EHV-1 seropositive. EHV-4 specific antibodies were detected in 237 (81.7%) of 290 horse sera tested. Results from this investigation demonstrate that EHV-1 and EHV-4 are prevalent throughout the equid population, and that donkeys and mules might also represent an important source of infection for other equids. We also showed that the multiplex nested PCR assay might be useful for diagnosis of mixed respiratory infections in horses due to EHV-1 and EHV-4.

Stopover ecology of a migratory ungulate

USGS Publications Warehouse

Sawyer, Hall; Kauffman, Matthew J.

2011-01-01

1. Birds that migrate long distances use stopover sites to optimize fuel loads and complete migration as quickly as possible. Stopover use has been predicted to facilitate a time-minimization strategy in land migrants as well, but empirical tests have been lacking, and alternative migration strategies have not been considered. 2. We used fine-scale movement data to evaluate the ecological role of stopovers in migratory mule deer Odocoileus hemionus— a land migrant whose fitness is strongly influenced by energy intake rather than migration speed. 3. Although deer could easily complete migrations (range 18–144 km) in several days, they took an average of 3 weeks and spent 95% of that time in a series of stopover sites that had higher forage quality than movement corridors. Forage quality of stopovers increased with elevation and distance from winter range. Mule deer use of stopovers corresponded with a narrow phenological range, such that deer occupied stopovers 44 days prior to peak green-up, when forage quality was presumed to be highest. Mule deer used one stopover for every 5∙3 and 6∙7 km travelled during spring and autumn migrations, respectively, and used the same stopovers in consecutive years. 4. Study findings indicate that stopovers play a key role in the migration strategy of mule deer by allowing individuals to migrate in concert with plant phenology and maximize energy intake rather than speed. Our results suggest that stopover use may be more common among non-avian taxa than previously thought and, although the underlying migration strategies of temperate ungulates and birds are quite different, stopover use is important to both. 5. Exploring the role of stopovers in land migrants broadens the scope of stopover ecology and recognizes that the applied and theoretical benefits of stopover ecology need not be limited to avian taxa.

Health status and relative exposure of mule deer and white-tailed deer to soil contaminants at the rocky mountain arsenal

USGS Publications Warehouse

Creekmore, Terry E.; Whittaker, Donald G.; Roy, Richard R.; Franson, J. Christian; Baker, Dan L.

1999-01-01

We evaluated the health of 18 radio-collared deer [13 mule deer (Odocoileus hemionus) and 5 white-tailed deer (O. virginianus)] from the Rocky Mountain Arsenal, near Denver, Colorado, USA, a Superfund site contaminated with a variety of materials, including organochlorine pesticides, metals, and nerve gas production by-products. Radio-collared deer were tracked for 1 to 3 years (1989–1992) to identify relative exposure to contaminants based on telemetry locations plotted on grid maps depicting known soil contaminant concentrations. At the end of the study, all animals were in fair or good body condition at the time of necropsy. Mean ages of mule deer and white-tailed deer were 7.4 (range 4–12) and 10.6 years (range 5–17), respectively. At necropsy, tissues were collected from the deer for serology, histopathology, and analysis for eight chlorinated hydrocarbons and two metals. Detectable residues of mercury were found in the kidneys of 10 deer (range 0.055–0.096 μg/g), dieldrin was found in fat (n = 9) (range 0.02–0.72 μg/g), liver (n = 4) (range 0.017–0.12 μg/g), and brain (n = 1, 0.018 μg/g), and DDE was found in the muscle of one animal (0.02 μg/g). Relative exposure estimates derived from telemetry and soil contamination data were correlated with tissue levels of dieldrin (p < 0.001) and mercury (p = 0.05). Two mule deer had severe testicular atrophy, and one of these animals also had antler deformities. The prevalence of antibodies against epizootic hemorrhagic disease serotype 2 was 85%.

Body weight and rumen-reticulum capacity in tule elk and mule deer

USGS Publications Warehouse

Weckerly, F.W.; Bleich, V.C.; Chetkiewicz, C.-L.B.; Ricca, M.A.

2003-01-01

The relationship between body size and rumen-reticulum capacity among conspecific individuals is predicted to be isometric. We examined whether the relationship between body weight and rumen-reticulum capacity was isometric in adult male and female rule elk (Cervus elaphus nannodes) and in adult female mule deer (Odocoileus hemionus). We detected no effect of sex on this relationship in elk, and the slope of the regression was 1.0 for one measure of rumen-reticulum capacity and <1.0 for another. Among deer, the slope of the relationship was <1.0 in one measure of rumen-reticulum capacity, and we detected no relationship with the other.

Healthcare Supported by Data Mule Networks in Remote Communities of the Amazon Region

PubMed Central

Coutinho, Mauro Margalho; Efrat, Alon; Richa, Andrea

2014-01-01

This paper investigates the feasibility of using boats as data mule nodes, carrying medical ultrasound videos from remote and isolated communities in the Amazon region in Brazil, to the main city of that area. The videos will be used by physicians to perform remote analysis and follow-up routine of prenatal examinations of pregnant women. Two open source simulators (the ONE and NS-2) were used to evaluate the results obtained utilizing a CoDPON (continuous displacement plan oriented network). The simulations took into account the connection times between the network nodes (boats) and the number of nodes on each boat route. PMID:27433519

MOLECULAR SURVEILLANCE FOR BARTONELLA, BORRELIA, AND RICKETTSIA SPECIES IN TICKS FROM DESERT BIGHORN SHEEP ( OVIS CANADENSIS) AND MULE DEER ( ODOCOILEUS HEMIONUS) IN SOUTHERN CALIFORNIA, USA.

PubMed

Billeter, Sarah A; Osikowicz, Lynn M; Burns, Joseph E; Konde, Lora; Gonzales, Ben J; Hu, Renjie; Kosoy, Michael Y

2018-01-01

:  Ticks (Acari: Ixodidae) were collected from 44 desert bighorn sheep ( Ovis canadensis) and 10 mule deer ( Odocoileus hemionus) in southern California, US during health inspections in 2015-16. Specimens were identified and screened by PCR analysis to determine the presence and prevalence of Bartonella, Borrelia, and Rickettsia species in ticks associated with these wild ruminants. None of the 60 Dermacentor hunteri and 15 Dermacentor albipictus ticks tested yielded positive PCR results. Additional tick specimens should be collected and tested to determine the prevalence of these confirmed or suspected tickborne pathogens within ruminant populations.

Application of the Hands-On Donkey Tool for Assessing the Welfare of Working Equids at Tuliman, Mexico.

PubMed

Galindo, F; de Aluja, A; Cagigas, R; Huerta, L A; Tadich, T A

2018-01-01

Equids are still used for diverse chores in Mexico and are essential for the livelihoods of numerous families. Appropriate health and behavior are prerequisites for performing work without affecting welfare. This study aimed to assess the welfare of working equids in Tuliman, applying the hands-on donkey tool. This tool evaluates five dimensions (behavior, body condition score [BCS], wounds, lameness, and other health issues) and was applied to 438 working equids (horses, mules, and donkeys). The Kruskall-Wallis test was applied to investigate differences between species and sex. Donkeys were more common; they also presented more positive behaviors and less lameness (p < 0.05). No differences were found for BCS among species on a scale ranging from 1 to 5 (mean BCS for donkeys = 1.9; mules = 2; and horses = 1.8). Mares had significantly lower BCS (mean = 1.5) than stallions (p < 0.05) and geldings (mean = 1.9). Overall mules had better welfare evaluations. The tool allowed detection of welfare issues in working equids; a practical outcome would be implementing local welfare strategies according to its results.

Ungulate exclusion, conifer thinning and mule deer forage in northeastern New Mexico

USGS Publications Warehouse

Kramer, David W.; Sorensen, Grant E.; Taylor, Chase A.; Cox, Robert D.; Gipson, Philip S.; Cain, James W.

2015-01-01

The southwestern United States has experienced expansion of conifer species (Juniperus spp. and Pinus ponderosa) into areas of semi-arid grassland over the past century. The expansion of conifers can limit palatable forage and reduce grass and forb communities. Conifer species are sometimes thinned through hydraulic mulching or selective cutting. We assessed the effects of these treatments on mule deer (Odocoileus hemionus) habitat in northeastern New Mexico to determine if conifer thinning improved cover of preferred forage species for mule deer in areas with and without ungulates. We measured plant cover and occurrence of preferred forage species in the summers of 2011 and 2012. An ongoing regional drought probably reduced vegetation response, with preferred forage species and herbaceous cover responding to conifer thinning or ungulate exclusion immediately following treatment, but not the following year. In 2011, areas that received thinning treatments had a higher abundance of preferred forage when compared to sites with no treatment. Grass coverage exhibited an immediate response in 2011, with ungulate exclosures containing 8% more coverage than areas without exclosures. The results suggest that conifer thinning and ungulate exclusion may elicit a positive response, however in the presence of drought; the positive effects are only short-term.

The deep layers of a Paleozoic arc: geochemistry of the Copley-Balaklala series, northern California

NASA Astrophysics Data System (ADS)

Brouxel, Marc; Lapierre, Henriette; Michard, Annie; Albarède, Francis

1987-10-01

REE, Zr, Nb concentrations and Sr, Nd isotope compositions have been measured in Copley basalts and andesites, Balaklala rhyolites, and Mule Mountain trondhjemites (northern California) which represent the deep layers of a well preserved intra-oceanic island arc of Siluro-Devonian age. 87Sr/ 86Sr is shifted towards high values (up to 0.707) whereas Ce is preferentially removed from rhyolites. A large proportion of the analyzed samples including some acidic rocks shows a pronounced depletion in light REE. The ɛ Nd(T) values of most Copley, Balaklala, and Mule Mountain rocks fall in the range +6 to +8 which suggests that they originated from a normal MORB-type source ( ɛ Nd(T) ≈ +9 ) contaminated with either sediments or an OIB-type component. In modern island arcs, only the shallow levels are accessible: comparison with the Copley-Balaklala-Mule Mountain Series suggests that, at depth, an immature island arc is likely to comprise thick layers of LILE-depleted tholeiites and rhyolites intensely altered by pervasive circulation of seawater. Least-square solutions of trace element models suggest that rhyolites and trondhjemites represent remelting of mafic volcanics from the arc basement rather than residual melts of basalt-andesite differentiation.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Daniel Steven; Efroymson, Rebecca Ann; Hargrove, William Walter

A multiple stressor risk assessment was conducted at Yuma Proving Ground, Arizona, as a demonstration of the Military Ecological Risk Assessment Framework. The focus was a testing program at Cibola Range, which involved an Apache Longbow helicopter firing Hellfire missiles at moving targets, M60- A1 tanks. This paper describes the ecological risk assessment for the missile launch and detonation. The primary stressor associated with this activity was sound. Other minor stressors included the detonation impact, shrapnel, and fire. Exposure to desert mule deer (Odocoileus hemionus crooki) was quantified using the Army sound contour program BNOISE2, as well as distances frommore » the explosion to deer. Few effects data were available from related studies. Exposure-response models for the characterization of effects consisted of human "disturbance" and hearing damage thresholds in units of C-weighted decibels (sound exposure level) and a distance-based No Observed Adverse Effects Level for moose and cannonfire. The risk characterization used a weight-of-evidence approach and concluded that risk to mule deer behavior from the missile firing was likely for a negligible number of deer, but that no risk to mule deer abundance and reproduction is expected.« less

Non-invasive genetic sampling of Southern Mule Deer (Odocoileus hemionus fuliginatus) reveals limited movement across California State Route 67 in San Diego County

USGS Publications Warehouse

Mitelberg, Anna; Vandergast, Amy

2016-01-01

—The Southern Mule Deer is a mobile but non-migratory large mammal found throughout southern California and is a covered species in the San Diego Multi-Species Conservation Plan. We assessed deer movement and population connectivity across California State Route 67 and two smaller roads in eastern San Diego County using non-invasive genetic sampling. We collected deer scat pellets between April and November 2015, and genotyped pellets at 15 microsatellites and a sex determination marker. We successfully genotyped 71 unique individuals from throughout the study area and detected nine recapture events. Recaptures were generally found close to original capture locations (within 1.5 km). We did not detect recaptures across roads; however, pedigree analysis detected 21 first order relative pairs, of which approximately 20% were found across State Route 67. Exact tests comparing allele frequencies between groups of individuals in pre-defined geographic clusters detected significant genetic differentiation across State Route 67. In contrast, the assignment-based algorithm of STRUCTURE supported a single genetic cluster across the study area. Our data suggest that State Route 67 may reduce, but does not preclude, movement and gene flow of Southern Mule Deer.

Sequence analysis of the msp4 gene of Anaplasma ovis strains

USGS Publications Warehouse

de la Fuente, J.; Atkinson, M.W.; Naranjo, V.; Fernandez de Mera, I. G.; Mangold, A.J.; Keating, K.A.; Kocan, K.M.

2007-01-01

Anaplasma ovis (Rickettsiales: Anaplasmataceae) is a tick-borne pathogen of sheep, goats and wild ruminants. The genetic diversity of A. ovis strains has not been well characterized due to the lack of sequence information. In this study, we evaluated bighorn sheep (Ovis canadensis) and mule deer (Odocoileus hemionus) from Montana for infection with A. ovis by serology and sequence analysis of the msp4 gene. Antibodies to Anaplasma spp. were detected in 37% and 39% of bighorn sheep and mule deer analyzed, respectively. Four new msp4 genotypes were identified. The A. ovis msp4 sequences identified herein were analyzed together with sequences reported previously for the characterization of the genetic diversity of A. ovis strains in comparison with other Anaplasma spp. The results of these studies demonstrated that although A. ovis msp4 genotypes may vary among geographic regions and between sheep and deer hosts, the variation observed was less than the variation observed between A. marginale and A. phagocytophilum strains. The results reported herein further confirm that A. ovis infection occurs in natural wild ruminant populations in Western United States and that bighorn sheep and mule deer may serve as wildlife reservoirs of A. ovis. ?? 2006.

Hydrology of an abandoned coal-mining area near McCurtain, Haskell County, Oklahoma

USGS Publications Warehouse

Slack, L.J.

1983-01-01

Water quality was investigated from October 1980 to May 1983 in an area of abandoned coal mines in Haskell county, Oklahoma. Bedrock in the area is shale, siltstone, sandstone, and the McAlester (Stigler) and Hartshorne coals of the McAlester Formation and Hartshorne Sandstone of Pennsylvanian age. The two coal beds, upper and lower Hartshorne, associated with the Hartshorne Sandstone converge or are separated by a few feet or less of bony coal or shale in the McCurtain area. Many small faults cut the Hartshorne coal in all the McCurtain-area mines. The main avenues of water entry to and movement through the bedrock are the exposed bedding-plane openings between layers of sandstone, partings between laminae of shale, fractures and joints developed during folding and faulting laminae of shale, fractures and joints developed during folding and faulting of the brittle rocks, and openings caused by surface mining--the overburden being shattered and broken to form spoil. Water-table conditions exist in bedrock and spoil in the area. Mine pond water is in direct hydraulic connections with water in the spoil piles and the underlying Hartshorne Sandstone. Sulfate is the best indicator of the presence of coal-mine drainage in both surface and ground water in the Oklahoma coal field. Median sulfate concentrations for four sites on Mule Creek ranged from 26 to 260 milligrams per liter. Median sulfate concentrations increased with increased drainage from unreclaimed mined areas. The median sulfate concentration in Mule Creek where it drains the reclaimed area is less than one-third of that at the next site downstream where the stream begins to drain abandoned (unreclaimed) mine lands. Water from Mule Creek predominantly is a sodium sulfate type. Maximum and median values for specific conductance and concentrations of calcium, magnesium, sodium, sulfate, chloride, dissolved solids, and alkalinity increase as Mule Creek flows downstream and drains increasing areas of abandoned (unreclaimed) mining lands. Constituent concentrations in Mule Creek, except those for dissolved solids, iron, manganese, and sulfate, generally do not exceed drinking-water limits. Reclamation likely would result in decreased concentrations of dissolved solids, calcium, magnesium, sodium, sulfate, and alkalinity in Mule Creek in the vicinity of the reclaimed area. Ground water in the area is moderately hard to very hard alkaline water with a median pH of 7.2 to 7.6. It predominately is a sodium sulfate type and, except for dissolved solids, iron manganese, and sulfate, constituent concentrations generally do not exceed drinking-water limits. Ground-water quality would likely be unchanged by reclamation. The quality of water in the two mine ponds is quite similar to that of the shallow ground water in the area. Constituents in water from both ponds generally do not exceed drinking-water limits and the water quality is unlikely to be changed by reclamation in the area.

Selection for Duration of Fertility and Mule Duck White Plumage Colour in a Synthetic Strain of Ducks (Anas platyrhynchos).

PubMed

Liu, H C; Huang, J F; Lee, S R; Liu, H L; Hsieh, C H; Huang, C W; Huang, M C; Tai, C; Poivey, J P; Rouvier, R; Cheng, Y S

2015-05-01

A synthetic strain of ducks (Anas platyrhynchos) was developed by introducing genes for long duration of fertility to be used as mother of mule ducklings and a seven-generation selection experiment was conducted to increase the number of fertile eggs after a single artificial insemination (AI) with pooled Muscovy semen. Reciprocal crossbreeding between Brown Tsaiya LRI-2 (with long duration of fertility) and Pekin L-201 (with white plumage mule ducklings) ducks produced the G0. Then G1 were intercrossed to produce G2 and so on for the following generations. Each female duck was inseminated 3 times, at 26, 29, and 32 weeks of age. The eggs were collected for 14 days from day 2 after AI. Individual data regarding the number of incubated eggs (Ie), the number of fertile eggs at candling at day 7 of incubation (F), the total number of dead embryos (M), the maximum duration of fertility (Dm) and the number of hatched mule ducklings (H) with plumage colour were recorded. The selection criterion was the breeding values of the best linear unbiased prediction animal model for F. The results show high percentage of exhibited heterosis in G2 for traits to improve (19.1% for F and 12.9% for H); F with a value of 5.92 (vs 3.74 in the Pekin L-201) was improved in the G2. Heritabilities were found to be low for Ie (h (2) = 0.07±0.03) and M (h (2) = 0.07±0.01), moderately low for Dm (h (2) = 0.13±0.02), of medium values for H (h (2) = 0.20±0.03) and F (h (2) = 0.23±0.03). High and favourable genetic correlations existed between F and Dm (rg = 0.93), between F and H (rg = 0.97) and between Dm and H (rg = 0.90). The selection experiment showed a positive trend for phenotypic values of F (6.38 fertile eggs in G10 of synthetic strain vs 5.59 eggs in G4, and 3.74 eggs in Pekin L-201), with correlated response for increasing H (5.73 ducklings in G10 vs 4.86 in G4, and 3.09 ducklings in Pekin L-201) and maximum duration of the fertile period without increasing the embryo mortality rate. The average predicted genetic response for F was 40% of genetic standard deviation per generation of selection. The mule ducklings' feather colour also was improved. It was concluded that this study provided results for a better understanding of the genetics of the duration of fertility traits in the common female duck bred for mule and that the selection of a synthetic strain was effective method of improvement.

Compensatory mortality in mule deer populations. Technical progress report

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G.C.

1986-03-15

The hypothesis of compensatory mortality is critical to understanding population dynamics of wildlife species. This is vital regardless of whether populations are managed for recreational hunting or habitats are altered via energy development projects. The purpose of research summarized herein is to test for compensatory mortality during winter in the juvenile (fawn) portion of a mule deer population. In the fall of 1985, sixty fawns were radio collared on both the control and treatment sites of the Little Hills study area. Thirty-three adult females also were telemetered, bringing the total instrumented population to 167 at the onset of winter. 10more » refs., 1 fig., 6 tabs.« less

Equine protozoal myeloencephalitis due to Neospora hughesi and equine motor neuron disease in a mule.

PubMed

Finno, Carrie J; Eaton, Joshua Seth; Aleman, Monica; Hollingsworth, Steven R

2010-07-01

A 23-year-old female mule was presented for bilateral ocular abnormalities and an abnormal pelvic limb gait. Anisocoria, unilateral enophthalmos, medial strabismus, ptosis, pupillary light reflex deficits, and bilateral reticulated pigmentary retinopathy were observed on ophthalmic examination. Neurologic abnormalities included right-sided facial nerve paralysis, extensive symmetric muscle atrophy, and asymmetric pelvic limb ataxia with an abnormal pelvic limb gait. A positive titer (1:40) for equine protozoal myeloencephalitis (EPM) associated with Neospora hughesi was obtained from cerebrospinal fluid with minimal (<1 red blood cell/microL) blood contamination. Muscle biopsies of the sacrocaudalis dorsalis medialis muscle revealed predominantly type I neurogenic muscle atrophy, consistent with a diagnosis of equine motor neuron disease (EMND). Treatment included a 2-month course of ponazuril (5 mg/kg PO q24 h), vitamin E (8000 IU PO q24 h), and selenium (2 mg PO q24 h). Clinical improvement was not observed after 2 months although the mule remained stable. Clinical deterioration was reported upon discontinuation of the ponazuril after a 2-month course. Concurrent disease with EPM associated with N. hughesi and EMND should be considered in cases demonstrating cranial nerve abnormalities, pronounced symmetric muscle atrophy, unusual asymmetric gait abnormalities, and reticulated pigmentary retinopathy.

Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein.

PubMed

Sandberg, Malin K; Al-Doujaily, Huda; Sigurdson, Christina J; Glatzel, Markus; O'Malley, Catherine; Powell, Caroline; Asante, Emmanuel A; Linehan, Jacqueline M; Brandner, Sebastian; Wadsworth, Jonathan D F; Collinge, John

2010-10-01

Chronic wasting disease (CWD) is a prion disease that affects free-ranging and captive cervids, including mule deer, white-tailed deer, Rocky Mountain elk and moose. CWD-infected cervids have been reported in 14 USA states, two Canadian provinces and in South Korea. The possibility of a zoonotic transmission of CWD prions via diet is of particular concern in North America where hunting of cervids is a popular sport. To investigate the potential public health risks posed by CWD prions, we have investigated whether intracerebral inoculation of brain and spinal cord from CWD-infected mule deer transmits prion infection to transgenic mice overexpressing human prion protein with methionine or valine at polymorphic residue 129. These transgenic mice have been utilized in extensive transmission studies of human and animal prion disease and are susceptible to BSE and vCJD prions, allowing comparison with CWD. Here, we show that these mice proved entirely resistant to infection with mule deer CWD prions arguing that the transmission barrier associated with this prion strain/host combination is greater than that observed with classical BSE prions. However, it is possible that CWD may be caused by multiple prion strains. Further studies will be required to evaluate the transmission properties of distinct cervid prion strains as they are characterized.

Mule deer spatial association patterns and potential implications for transmission of an epizootic disease.

PubMed

Mejía-Salazar, María Fernanda; Goldizen, Anne W; Menz, Clementine S; Dwyer, Ross G; Blomberg, Simon P; Waldner, Cheryl L; Cullingham, Catherine I; Bollinger, Trent K

2017-01-01

Animal social behaviour can have important effects on the long-term dynamics of diseases. In particular, preferential spatial relationships between individuals can lead to differences in the rates of disease spread within a population. We examined the concurrent influence of genetic relatedness, sex, age, home range overlap, time of year, and prion disease status on proximal associations of adult Rocky Mountain mule deer (Odocoileus hemionus hemionus) in a chronic wasting disease endemic area. We also quantified the temporal stability of these associations across different sex, age, and disease status classes. We used three years of high frequency telemetry data from 74 individuals to record encounters within 25 m of each other, and to calculate seasonal home range overlap measured by volume of intersection (VI). The strength of pairwise spatial association between adult mule deer was independent of genetic relatedness, age and disease status. Seasonal variation in association strength was not consistent across years, perhaps due to annual changes in weather conditions. The influence of home range overlap on association strength varied seasonally, whereby associations were stronger in pre-rut and fawning than in the rest of the seasons. The sexes of individuals also interacted with both VI and season. At increasing levels of VI, associations were stronger between females than between males and between females and males. The strongest associations in pre-rut were between males, while the strongest in rut were between females and males. The temporal stability of associations was markedly dependant on the sex and the diagnosis of the associating pair. Our findings highlight the importance of considering concurrent effects of biological and environmental factors when seeking to understand the role of social preference in behavioural ecology and disease spread. Applying this knowledge in epidemiological modelling will shed light on the dynamics of disease transmission among mule deer.

Weather and Prey Predict Mammals' Visitation to Water.

PubMed

Harris, Grant; Sanderson, James G; Erz, Jon; Lehnen, Sarah E; Butler, Matthew J

2015-01-01

Throughout many arid lands of Africa, Australia and the United States, wildlife agencies provide water year-round for increasing game populations and enhancing biodiversity, despite concerns that water provisioning may favor species more dependent on water, increase predation, and reduce biodiversity. In part, understanding the effects of water provisioning requires identifying why and when animals visit water. Employing this information, by matching water provisioning with use by target species, could assist wildlife management objectives while mitigating unintended consequences of year-round watering regimes. Therefore, we examined if weather variables (maximum temperature, relative humidity [RH], vapor pressure deficit [VPD], long and short-term precipitation) and predator-prey relationships (i.e., prey presence) predicted water visitation by 9 mammals. We modeled visitation as recorded by trail cameras at Sevilleta National Wildlife Refuge, New Mexico, USA (June 2009 to September 2014) using generalized linear modeling. For 3 native ungulates, elk (Cervus Canadensis), mule deer (Odocoileus hemionus), and pronghorn (Antilocapra americana), less long-term precipitation and higher maximum temperatures increased visitation, including RH for mule deer. Less long-term precipitation and higher VPD increased oryx (Oryx gazella) and desert cottontail rabbits (Sylvilagus audubonii) visitation. Long-term precipitation, with RH or VPD, predicted visitation for black-tailed jackrabbits (Lepus californicus). Standardized model coefficients demonstrated that the amount of long-term precipitation influenced herbivore visitation most. Weather (especially maximum temperature) and prey (cottontails and jackrabbits) predicted bobcat (Lynx rufus) visitation. Mule deer visitation had the largest influence on coyote (Canis latrans) visitation. Puma (Puma concolor) visitation was solely predicted by prey visitation (elk, mule deer, oryx). Most ungulate visitation peaked during May and June. Coyote, elk and puma visitation was relatively consistent throughout the year. Within the diel-period, activity patterns for predators corresponded with prey. Year-round water management may favor species with consistent use throughout the year, and facilitate predation. Providing water only during periods of high use by target species may moderate unwanted biological costs.

Weather and Prey Predict Mammals’ Visitation to Water

PubMed Central

Harris, Grant; Sanderson, James G.; Erz, Jon; Lehnen, Sarah E.; Butler, Matthew J.

2015-01-01

Throughout many arid lands of Africa, Australia and the United States, wildlife agencies provide water year-round for increasing game populations and enhancing biodiversity, despite concerns that water provisioning may favor species more dependent on water, increase predation, and reduce biodiversity. In part, understanding the effects of water provisioning requires identifying why and when animals visit water. Employing this information, by matching water provisioning with use by target species, could assist wildlife management objectives while mitigating unintended consequences of year-round watering regimes. Therefore, we examined if weather variables (maximum temperature, relative humidity [RH], vapor pressure deficit [VPD], long and short-term precipitation) and predator-prey relationships (i.e., prey presence) predicted water visitation by 9 mammals. We modeled visitation as recorded by trail cameras at Sevilleta National Wildlife Refuge, New Mexico, USA (June 2009 to September 2014) using generalized linear modeling. For 3 native ungulates, elk (Cervus Canadensis), mule deer (Odocoileus hemionus), and pronghorn (Antilocapra americana), less long-term precipitation and higher maximum temperatures increased visitation, including RH for mule deer. Less long-term precipitation and higher VPD increased oryx (Oryx gazella) and desert cottontail rabbits (Sylvilagus audubonii) visitation. Long-term precipitation, with RH or VPD, predicted visitation for black-tailed jackrabbits (Lepus californicus). Standardized model coefficients demonstrated that the amount of long-term precipitation influenced herbivore visitation most. Weather (especially maximum temperature) and prey (cottontails and jackrabbits) predicted bobcat (Lynx rufus) visitation. Mule deer visitation had the largest influence on coyote (Canis latrans) visitation. Puma (Puma concolor) visitation was solely predicted by prey visitation (elk, mule deer, oryx). Most ungulate visitation peaked during May and June. Coyote, elk and puma visitation was relatively consistent throughout the year. Within the diel-period, activity patterns for predators corresponded with prey. Year-round water management may favor species with consistent use throughout the year, and facilitate predation. Providing water only during periods of high use by target species may moderate unwanted biological costs. PMID:26560518

Mule deer spatial association patterns and potential implications for transmission of an epizootic disease

PubMed Central

Goldizen, Anne W.; Menz, Clementine S.; Dwyer, Ross G.; Blomberg, Simon P.; Waldner, Cheryl L.; Cullingham, Catherine I.; Bollinger, Trent K.

2017-01-01

Animal social behaviour can have important effects on the long-term dynamics of diseases. In particular, preferential spatial relationships between individuals can lead to differences in the rates of disease spread within a population. We examined the concurrent influence of genetic relatedness, sex, age, home range overlap, time of year, and prion disease status on proximal associations of adult Rocky Mountain mule deer (Odocoileus hemionus hemionus) in a chronic wasting disease endemic area. We also quantified the temporal stability of these associations across different sex, age, and disease status classes. We used three years of high frequency telemetry data from 74 individuals to record encounters within 25 m of each other, and to calculate seasonal home range overlap measured by volume of intersection (VI). The strength of pairwise spatial association between adult mule deer was independent of genetic relatedness, age and disease status. Seasonal variation in association strength was not consistent across years, perhaps due to annual changes in weather conditions. The influence of home range overlap on association strength varied seasonally, whereby associations were stronger in pre-rut and fawning than in the rest of the seasons. The sexes of individuals also interacted with both VI and season. At increasing levels of VI, associations were stronger between females than between males and between females and males. The strongest associations in pre-rut were between males, while the strongest in rut were between females and males. The temporal stability of associations was markedly dependant on the sex and the diagnosis of the associating pair. Our findings highlight the importance of considering concurrent effects of biological and environmental factors when seeking to understand the role of social preference in behavioural ecology and disease spread. Applying this knowledge in epidemiological modelling will shed light on the dynamics of disease transmission among mule deer. PMID:28388681

Detection of QTL controlling metabolism, meat quality, and liver quality traits of the overfed interspecific hybrid mule duck.

PubMed

Kileh-Wais, M; Elsen, J M; Vignal, A; Feves, K; Vignoles, F; Fernandez, X; Manse, H; Davail, S; André, J M; Bastianelli, D; Bonnal, L; Filangi, O; Baéza, E; Guéméné, D; Genêt, C; Bernadet, M D; Dubos, F; Marie-Etancelin, C

2013-02-01

The mule duck, an interspecific hybrid obtained by crossing common duck (Anas platyrhynchos) females with Muscovy (Cairina moschata) drakes, is widely used for fatty liver production. The purpose of the present study was to detect and map single and pleiotropic QTL that segregate in the common duck species, and influence the expression of traits in their overfed mule duck offspring. To this end, we generated a common duck backcross (BC) population by crossing Kaiya and heavy Pekin experimental lines, which differ notably in regard to the BW and overfeeding ability of their mule progeny. The BC females were mated to Muscovy drakes and, on average, 4 male mule ducks hatched per BC female (1600 in total) and were measured for growth, metabolism during growth and the overfeeding period, overfeeding ability, and the quality of their breast meat and fatty liver. The phenotypic value of BC females was estimated for each trait by assigning to each female the mean value of the phenotypes of her offspring. Estimations allowed for variance, which depended on the number of male offspring per BC and the heritability of the trait considered. The genetic map used for QTL detection consisted of 91 microsatellite markers aggregated into 16 linkage groups (LG) covering a total of 778 cM. Twenty-two QTL were found to be significant at the 1% chromosome-wide threshold level using the single-trait detection option of the QTLMap software. Most of the QTL detected were related to the quality of breast meat and fatty liver: QTL for meat pH 20 min post mortem were mapped to LG4 (at the 1% genome-wide significance level), and QTL for meat lipid content and cooking losses were mapped to LG2a. The QTL related to fatty liver weight and liver protein and lipid content were for the most part detected on LG2c and LG9. Multitrait analysis highlighted the pleiotropic effects of QTL in these chromosome regions. Apart from the strong QTL for plasma triglyceride content at the end of the overfeeding period mapped to chromosome Z using single-trait analysis, all metabolic trait QTL were detected with the multitrait approach: the QTL mapped to LG14 and LG21 affected the plasma cholesterol and triglyceride contents, whereas the QTL mapped to LG2a seemed to impact glycemia and the basal plasma corticosterone content. A greater density genetic map will be needed to further fine map the QTL.

Geologic setting and genesis of the Mule Canyon low-sulfidation epithermal gold-silver deposit, north-central Nevada

USGS Publications Warehouse

John, D.A.; Hofstra, A.H.; Fleck, R.J.; Brummer, J.E.; Saderholm, E.C.

2003-01-01

The Mule Canyon mine exploited shallow, low-sulfidation, epithermal Au-Ag deposits that lie near the west side of the Northern Nevada rift in northern Lander County, Nevada. Mule Canyon consists of six small deposits that contained premining reserves of about 8.2 Mt at an average grade of 3.81 g Au/tonne. It is an uncommon mafic end member of low-sulfidation Au-Ag deposits associated with tholeiitic bimodal basalt-rhyolite magmatism. The ore is hosted by a basalt-andesite eruptive center that formed between about 16.4 to 15.8 Ma during early mafic eruptions related to regionally extensive bimodal magmatism. Hydrothermal alteration and Au-Ag ores formed at about 15.6 Ma and were tightly controlled by north-northwest- to north-striking high-angle fault and breccia zones developed during rifting, emplacement of mafic dikes, and eruption of mafic lava flows. Hydrothermal alteration assemblages are zoned outward from fluid conduits in the sequence silica-adularia, adularia-smectite, smectite (intermediate argillic), and smectite-carbonate (propylitic). All alteration types contain abundant pyrite and/or marcasite ?? arsenopyrite. Field relations indicate that silica-adularia alteration is superimposed on argillic and propylitic alteration. Little or no steam-heated acid-sulfate alteration is present, probably the result of a near-surface water table during hydrothermal alteration and ore deposition. Two distinct ore types are present at Mule Canyon: early replacement and later open-space filling. Replacement ores consist of disseminated and vesicle-filling pyrite, marcasite, and arsenopyrite in argillically altered or weakly silicified rocks. Ore minerals consist of Au-bearing arsenopyrite and arsenian pyrite overgrowths on earlier-formed pyrite and marcasite. Open-space filling ores include narrow stockwork quartz-adularia veins, banded and crustiform opaline and chalcedonic silica-adularia veins, silica-adularia cemented breccias, and sparse carbonate-pyrite and/or marcasite veins. Ore minerals consist mostly of electrum and Ag sulfide and selenide minerals, with minor to major amounts of pyrite, marcasite, and arsenopyrite, and local stibnite. Both types of ores have similar geochemical signatures, characterized by high Au, Ag, As, Sb, and Se contents, locally high Hg, Mo, Tl, and W contents, and low Cu, Pb, and Zn contents. Stable isotope data indicate that ore fluids consisted dominantly of meteoric water that evolved by deep circulation through Paleozoic sedimentary rocks at low water/rock ratios (about 1) and high temperatures (>200??C). Calculated isotopic compositions of ore fluids are ??18OH2O = -3 to -7 per mil, ??DH2O = -107 to -124 per mil, ??13CCO2 = 0 to -6 per mil, and ??34SH2S = -3 to +8 per mil. The ore fluids obtained much of their H2S and CO2 and probably scavenged ore metals and trace elements from the Paleozoic sedimentary rocks. Some H2S and CO2 may have been derived from degassing Miocene magmas. Mule Canyon formed at shallow depths, probably about 100 m below the paleosurface. Ore fluids were dilute, nearly neutral in pH, reduced, H2S-rich, and CO2-bearing. Peak temperatures in ore zones reached 230?? to 265??C at nearly lithostatic pressures when some crystalline quartz ?? adularia precipitated, but most ore formed at temperatures <200??C at near hydrostatic pressures and was accompanied by precipitation of opaline and chalcedonic silica ?? adularia ?? calcite and dolomite. Deposition of gold in As-rich overgrowths on pyrite and/or marcasite in disseminated ores occurred owing to decreasing H2S in the ore fluids resulting from sulfidation reactions. Later electrum and Ag selenide precipitation in open spaces occurred owing to boiling, loss of H2S to the vapor phase, and cooling. Mule Canyon is similar to most other low-sulfidation Au-Ag deposits associated with Miocene tholeiitic bimodal basalt-rhyolite magmatism in the Great Basin, such as Sleeper, Midas, and Buckhorn. Major differences at Mule Canyon are

Characterization of Prdm9 in equids and sterility in mules.

PubMed

Steiner, Cynthia C; Ryder, Oliver A

2013-01-01

Prdm9 (Meisetz) is the first speciation gene discovered in vertebrates conferring reproductive isolation. This locus encodes a meiosis-specific histone H3 methyltransferase that specifies meiotic recombination hotspots during gametogenesis. Allelic differences in Prdm9, characterized for a variable number of zinc finger (ZF) domains, have been associated with hybrid sterility in male house mice via spermatogenic failure at the pachytene stage. The mule, a classic example of hybrid sterility in mammals also exhibits a similar spermatogenesis breakdown, making Prdm9 an interesting candidate to evaluate in equine hybrids. In this study, we characterized the Prdm9 gene in all species of equids by analyzing sequence variation of the ZF domains and estimating positive selection. We also evaluated the role of Prdm9 in hybrid sterility by assessing allelic differences of ZF domains in equine hybrids. We found remarkable variation in the sequence and number of ZF domains among equid species, ranging from five domains in the Tibetan kiang and Asiatic wild ass, to 14 in the Grevy's zebra. Positive selection was detected in all species at amino acid sites known to be associated with DNA-binding specificity of ZF domains in mice and humans. Equine hybrids, in particular a quartet pedigree composed of a fertile mule showed a mosaic of sequences and number of ZF domains suggesting that Prdm9 variation does not seem by itself to contribute to equine hybrid sterility.

Health status and relative exposure of mule deer and white-tailed deer to soil contaminants at the Rocky Mountain Arsenal

DOE Office of Scientific and Technical Information (OSTI.GOV)

Creekmore, T.E.; Franson, J.C.; Whittaker, D.G.

1999-02-01

The authors evaluated the health of 18 radio-collared deer [13 mule deer (Odocoileus hemionus) and 5 white-tailed deer (O. virginianus)] from the Rocky Mountain Arsenal, near Denver, Colorado, USA, a Superfund site contaminated with a variety of materials, including organochlorine pesticides, metals and nerve gas production by-products. Radio-collared deer were tracked for 1 to 3 years (1989--1992) to identify relative exposure to contaminants based on telemetry locations plotted on grid maps depicting known soil contaminant concentrations. At the end of the study, all animals were in fair or good body condition at the time of necropsy. Mean ages of mulemore » deer and white-tailed deer were 7.4 and 10.6 years, respectively. At necropsy, tissues were collected from the deer for serology, histopathology, and analysis for eight chlorinated hydrocarbons and two metals. Detectable residues of mercury were found in the kidneys of 10 deer, dieldrin was found in fat, liver, and brain, and DDE was found in the muscle of one animal. Relative exposure estimates derived from telemetry and soil contamination data were correlated with tissue levels of dieldrin and mercury. Two mule deer had severe testicular atrophy, and one of these animals also had antler deformities. The prevalence of antibodies against epizootic hemorrhagic disease serotype 2 was 85%.« less

Chlamydia psittaci in ducks: a hidden health risk for poultry workers.

PubMed

Vorimore, Fabien; Thébault, Anne; Poisson, Sonia; Cléva, Didier; Robineau, Joseph; de Barbeyrac, Bertille; Durand, Benoit; Laroucau, Karine

2015-02-01

Chlamydia psittaci is a zoonotic pathogen associated primarily with avian chlamydiosis also referred as psittacosis. Human psittacosis can lead to severe cases of respiratory disease. The mule duck is one of the main bird hybrids associated with human cases of psittacosis in France. In order to better understand the epidemiology of avian chlamydiosis, monitoring studies were performed in both breeder flocks and mule duck flocks. Surveys conducted in one professional duck bredding organization revealed little shedding in breeder flocks, whereas heavy but asymptomatic C. psittaci shedding was observed in most of the mule duck flocks, mostly when birds were reared in open range conditions on farms. Human cases of psittacosis linked to duck breeder flocks and their progeny led to detection of heavy shedders in all the suspected flocks despite no birds showing clinical signs. Offspring of one of the infected female flocks was analyzed and also proved to be infected by C. psittaci. Field studies suggest that C. psittaci infections in duck farms involve horizontal and probably vertical transmission but that the environment also plays an important role in maintaining infection on farms. In the light of the widespread occurrence of C. psittaci on duck farms, it has become urgent to clearly identify sources of contamination in order to take appropriate field management measures to minimize worker exposure. © FEMS 2014. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Identifying and prioritizing ungulate migration routes for landscape-level conservation

USGS Publications Warehouse

Sawyer, Hall; Kauffman, Matthew J.; Nielson, Ryan M.; Horne, Jon S.

2009-01-01

As habitat loss and fragmentation increase across ungulate ranges, identifying and prioritizing migration routes for conservation has taken on new urgency. Here we present a general framework using the Brownian bridge movement model (BBMM) that: (1) provides a probabilistic estimate of the migration routes of a sampled population, (2) distinguishes between route segments that function as stopover sites vs. those used primarily as movement corridors, and (3) prioritizes routes for conservation based upon the proportion of the sampled population that uses them. We applied this approach to a migratory mule deer (Odocoileus hemionus) population in a pristine area of southwest Wyoming, USA, where 2000 gas wells and 1609 km of pipelines and roads have been proposed for development. Our analysis clearly delineated where migration routes occurred relative to proposed development and provided guidance for on-the-ground conservation efforts. Mule deer migration routes were characterized by a series of stopover sites where deer spent most of their time, connected by movement corridors through which deer moved quickly. Our findings suggest management strategies that differentiate between stopover sites and movement corridors may be warranted. Because some migration routes were used by more mule deer than others, proportional level of use may provide a reasonable metric by which routes can be prioritized for conservation. The methods we outline should be applicable to a wide range of species that inhabit regions where migration routes are threatened or poorly understood.

Genomic and pathogenic analysis of a Muscovy duck parvovirus strain causing short beak and dwarfism syndrome without tongue protrusion.

PubMed

Fu, Qiuling; Huang, Yu; Wan, Chunhe; Fu, Guanghua; Qi, Baomin; Cheng, Longfei; Shi, Shaohua; Chen, Hongmei; Liu, Rongchang; Chen, Zhenhai

2017-12-01

In 2008, clinical cases of short beak and dwarfism syndrome (SBDS) caused by Muscovy duck parvovirus (MDPV) infection were found in mule duck and Taiwan white duck farms in Fujian, China. A MDPV LH strain causing duck SBDS without tongue protrusion was isolated in this study. Phylogenetic analysis show that the MDPV LH strain was clustered together with other MDPV strains, but divergent from GPV isolates. Two major fragment deletions were found in the inverted terminal repeats (ITR) of MDPV LH similar to the ones in the ITR of MDPV GX5, YY and SAAS-SHNH strains. To investigate the pathogenicity of the MDPV LH strain, virus infection of young mule ducks was performed. The infected ducks showed SBDS symptoms including retard growth and shorten beaks without tongue protrusion. Atrophy of thymus, spleen and bursa of Fabricius was identified in the infected ducks. The results show that MDPV LH strain is moderately pathogenic to mule duck, leading to occurrence of SBDS. As far as we know, it is the first study showing that SBDS without tongue protrusion, and atrophy of thymus, spleen and bursa of Fabricius possibly associated with immunosuppression were found in the MDPV-infected ducks. The established duck-MDPV-SBDS system will help us to further work on the virus pathogenesis and develop efficacious vaccine against MDPV infection. Copyright © 2017. Published by Elsevier Ltd.

Characterization of Prdm9 in Equids and Sterility in Mules

PubMed Central

Steiner, Cynthia C.; Ryder, Oliver A.

2013-01-01

Prdm9 (Meisetz) is the first speciation gene discovered in vertebrates conferring reproductive isolation. This locus encodes a meiosis-specific histone H3 methyltransferase that specifies meiotic recombination hotspots during gametogenesis. Allelic differences in Prdm9, characterized for a variable number of zinc finger (ZF) domains, have been associated with hybrid sterility in male house mice via spermatogenic failure at the pachytene stage. The mule, a classic example of hybrid sterility in mammals also exhibits a similar spermatogenesis breakdown, making Prdm9 an interesting candidate to evaluate in equine hybrids. In this study, we characterized the Prdm9 gene in all species of equids by analyzing sequence variation of the ZF domains and estimating positive selection. We also evaluated the role of Prdm9 in hybrid sterility by assessing allelic differences of ZF domains in equine hybrids. We found remarkable variation in the sequence and number of ZF domains among equid species, ranging from five domains in the Tibetan kiang and Asiatic wild ass, to 14 in the Grevy’s zebra. Positive selection was detected in all species at amino acid sites known to be associated with DNA-binding specificity of ZF domains in mice and humans. Equine hybrids, in particular a quartet pedigree composed of a fertile mule showed a mosaic of sequences and number of ZF domains suggesting that Prdm9 variation does not seem by itself to contribute to equine hybrid sterility. PMID:23613924

Effects of starch and fibre in pelleted diets on nutritional status of mule deer (Odocoileus hemionus) fawns.

PubMed

McCusker, S; Shipley, L A; Tollefson, T N; Griffin, M; Koutsos, E A

2011-08-01

To compare the effects of a low-starch, high-fibre diet [LSHF; 51.6% neutral detergent fibre (NDF), 3.0% starch, 14.8% crude protein (CP)] and a high-starch, low-fibre diet (HSLF; 33.3% NDF, 20.0% starch, 19.6% CP) on the nutritional status of captive exotic ruminants, 16 mule deer (Odocoileus hemionus) were fed one of these two diets ad libitum with ≤25% alfalfa hay cubes from 10 days to 68 weeks of age. During five sampling periods beginning in November and spaced 6-12 weeks apart thereafter, feed intake, rumen and blood chemistry, faecal scores, growth and body condition were measured. Dry matter intake, digestible energy intake, time spent ruminating and feeding and blood acetate concentration were greater for deer fed LSHF (p < 0.05 for all). Lower dietary CP led to reduced blood urea nitrogen for deer consuming LSHF (p = 0.004). Deer had the same faecal scores, growth and body fat among treatments (all p > 0.05). These findings show pelleted diets with less starch, more fibre, and reduced protein met the energy and protein requirements of growing mule deer, a medium-sized browsing ruminant, as well as traditional grain-based diets while more closely mimicking natural forages and stimulating a more natural feeding behaviour. © 2010 Blackwell Verlag GmbH.

9 CFR 93.200 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

..., swine, horses, asses, mules, zebras, dogs, and poultry. Communicable disease. Any contagious, infectious... duties required under this subpart. Operator. For the purpose of § 93.209, any person operating an...

Association mapping of genetic risk factors for chronic wasting disease in wild deer

USGS Publications Warehouse

Tomomi Matsumoto,; Samuel, Michael D.; Trent Bollinger,; Margo Pybus,; David W. Coltman,

2013-01-01

Chronic wasting disease (CWD) is a fatal transmissible spongiform encephalopathy affecting North American cervids. We assessed the feasibility of association mapping CWD genetic risk factors in wild white-tailed deer (Odocoileus virginianus) and mule deer (Odocoileus hemionus) using a panel of bovine microsatellite markers from three homologous deer linkage groups predicted to contain candidate genes. These markers had a low cross-species amplification rate (27.9%) and showed weak linkage disequilibrium (<1 cM). Markers near the prion protein and the neurofibromin 1 (NF1) genes were suggestively associated with CWD status in white-tailed deer (P = 0.006) and mule deer (P = 0.02), respectively. This is the first time an association between the NF1 region and CWD has been reported.

Large native ungulates

Treesearch

Bryce Rickel

2005-01-01

This chapter addresses the large native ungulates (American bison (Bos bison), elk (Cervus elaphus), white-tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), and pronghorn (Antilocapra americana) of the grasslands. The information presented includes...

Sex impact on the quality of fatty liver and its genetic determinism in mule ducks.

PubMed

Marie-Etancelin, C; Retailleau, B; Alinier, A; Vitezica, Z G

2015-09-01

Recent changes to French regulations now allow farmers to produce "foie gras" from both male and female mule ducks. The aim of this study was to assess the quality of female fatty liver and to compare, from a phenotypic and genetic point of view, liver quality in males and females. A total of 914 mule ducks (591 males and 323 females), hatched in a single pedigree batch, were reared until 86 d of age and then force-fed for 12 d, before being slaughtered. Carcasses and livers were weighed and liver quality was assessed by grading the extent of liver veining and measuring the liver melting rate, either after sterilization of 60 g of liver or pasteurization of 180 g of liver. Sexual dimorphism was observed in favor of males, with a difference of approximately 10% in carcass and liver weights and up to 54% for the liver melting rate. Moreover, one-third of female livers showed moderate to high veining, whereas this was not the case for male livers. The fatty livers of female mule ducks are, therefore, of poorer quality and could not be transformed into a product with the appellation "100% fatty liver." According to sex and parental line, heritability values ranged from 0.12 ± 0.05 to 0.18 ± 0.07 for fatty liver weight and from 0.09 ± 0.05 to 0.18 ± 0.05 for the 2 melting rate traits. The genetic correlations between the fatty liver weight and both melting rates were high (greater than +0.80) in the Muscovy population, whereas in the Pekin population, the liver weight and melting rates were less strongly correlated (estimates ranging from +0.36 ± 0.30 to +0.45 ± 0.28). Selection for lower liver melting rates without reducing the liver weight would, therefore, be easier to achieve in the Pekin population. Finally, as the 2 melting rate measurements are highly correlated (0.91 and over 0.95 for phenotypic and genetic correlations, respectively), we suggest using the easiest method, that is, sterilization of 60 g of liver.

9 CFR 75.1-75.3 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-01-01

... INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS COMMUNICABLE DISEASES IN HORSES, ASSES, PONIES, MULES, AND ZEBRAS Dourine in Horses and Asses §§ 75.1-75.3 [Reserved] Equine Infectious...

9 CFR 75.1-75.3 - [Reserved

Code of Federal Regulations, 2013 CFR

2013-01-01

... INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS COMMUNICABLE DISEASES IN HORSES, ASSES, PONIES, MULES, AND ZEBRAS Dourine in Horses and Asses §§ 75.1-75.3 [Reserved] Equine Infectious...

9 CFR 75.1-75.3 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-01-01

... INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS COMMUNICABLE DISEASES IN HORSES, ASSES, PONIES, MULES, AND ZEBRAS Dourine in Horses and Asses §§ 75.1-75.3 [Reserved] Equine Infectious...

9 CFR 75.1-75.3 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-01-01

... INTERSTATE TRANSPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS COMMUNICABLE DISEASES IN HORSES, ASSES, PONIES, MULES, AND ZEBRAS Dourine in Horses and Asses §§ 75.1-75.3 [Reserved] Equine Infectious...

38. Historic photograph, photographer unknown, c. 1944. VIEW SHOWING BURROS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

38. Historic photograph, photographer unknown, c. 1944. VIEW SHOWING BURROS (OR MULES) CROSSING BRIDGE, LOOKING NORTHEAST. - Verde River Sheep Bridge, Spanning Verde River (Tonto National Forest), Cave Creek, Maricopa County, AZ

26 CFR 20.2055-2 - Transfers not exclusively for charitable purposes.

Code of Federal Regulations, 2010 CFR

2010-04-01

..., hogs, horses, mules, donkeys, sheep, goats, captive furbearing animals, chickens, turkeys, pigeons, and... death or the alternate valuation date determined pursuant to an election under section 2032. (i) For...

26 CFR 20.2055-2 - Transfers not exclusively for charitable purposes.

Code of Federal Regulations, 2011 CFR

2011-04-01

..., hogs, horses, mules, donkeys, sheep, goats, captive furbearing animals, chickens, turkeys, pigeons, and... death or the alternate valuation date determined pursuant to an election under section 2032. (i) For...

Assessing impacts of oil-shale development on the Piceance Basin mule deer herd

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G.C.; Garrott, R.A.

Development of energy resources on big game ranges generally negatively impacts these important wildlife resources. Although habitat disturbance is generally important, this impact is overshadowed by the negative impacts due to an increasing human population in the area. Increased human activities particularly stress animals during winter periods when inadequate nutrition levels may have already severely impacted the population. Increased road traffic and poaching causes additional deaths, which a decline in survival rates expected, or at least changes in the cause of mortality. This paper describes the experimental design to monitor and mitigate the impact of oil shale development in northwesternmore » Colorado on the Piceance Basin mule deer herd. Biotelemetry techniques are used to measure changes through time in movements, habitat utilization, and survival rates between control and treatment areas. 2 figures.« less

Mule deer passage beneath an overland coal conveyor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Greenwood, C.L.; Dalton, L.B.

1984-07-31

Presently, information pertaining to migration and daily movement patterns of big game in relation to overland conveyors or large diameter pipelines is sparse. A literature review showed that moose, caribou, reindeer, and dall sheep will pass beneath or over large diameter pipeline systems. But no information was found relative to big game crossing coal conveyor systems. Mule deer passage beneath an overland coal conveyor in Carbon County, Utah, was studied during spring 1981. Deer avoided crossing at underpass opportunities where the clearance was less than 50 cm. Clearances between 50 and 90 cm were selected for crossing. Deer passed beneathmore » the conveyor during day and nighttime conditions and while the conveyor was either operating or idle. Recommendations are discussed for designing conveyors and pipelines to facilitate big game passage. 13 references, 2 tables.« less

Oil on the water: Government regulation of a carcinogen in the twentieth-century Lancashire cotton spinning industry.

PubMed

Higgins, David; Tweedale, Geoffrey

2010-01-01

In the Lancashire cotton textile industry, mule spinners were prone to a chronic and sometimes fatal skin cancer (often affecting the groin). The disease had reached epidemic proportions by the 1920s, which necessitated action by the government, employers, and trade unions. In contrast to previous accounts, this article focuses on the government's reaction to mule spinners' cancer. Using official records in the National Archives, the slow introduction of health and safety measures by the government is explored in detail. Although obstructionism by the employers played a key role, one of the reasons for government inaction was the ambiguity of scientific research on engineering oils. On the other hand, prolonged scientific research suited a government policy that was framed around self regulation - a policy that had proved largely ineffective by the 1950s.

Petrography and geochemistry characteristics of the lower Cretaceous Muling Formation from the Laoheishan Basin, Northeast China: implications for provenance and tectonic setting

NASA Astrophysics Data System (ADS)

Song, Yu; Liu, Zhaojun; Meng, Qingtao; Wang, Yimeng; Zheng, Guodong; Xu, Yinbo

2017-06-01

The petrography, mineralogy and geochemistry of sedimentary rocks from the lower Cretaceous Muling Formation (K1ml) in the Laoheishan basin, northeast (NE) China are studied to determine the weathering intensity, provenance and tectonic setting of the source region. Petrographic data indicate the average quartz-feldspar-lithic fragments (QFL) of the sandstone is Q = 63 %, F = 22 %, and L = 15 %. Lithic fragments mainly contain volcanic clasts that derived from surrounding basement. X-ray diffraction (XRD) data reveal abundant clay and detrital minerals (e.g. quartz), as well as minor calcite in the fine-grained sediments. The Hf contents and element concentration ratios such as Al2O3/TiO2, Co/Th, La/Sc, and La/Th are comparable to sediments derived from felsic and intermediate igneous rocks. The strong genetic relationship with the igneous rocks from the northwest and northeast areas provides evidence that the sediments of the Muling Formation (K1ml) in the Laoheishan basin have been derived from this area. The chemical index of alteration (CIA) and index of chemical variability (ICV) reveal an intensive weathering in the source region of the sediments. The multidimensional tectonic discrimination diagrams indicate that the source rocks of K1ml are mainly derived from the collision system. However, they may also comprise sediments derived from the continental rift system. The results are consistent with the geology of the study area.

An evaluation of a mitigation strategy for deer-vehicle collisions

USGS Publications Warehouse

Bissonette, John A.; Rosa, Silvia

2012-01-01

High mule deer Odocoileus hemionus mortality in southwestern Utah led to the establishment of a mitigation strategy with two major objectives: 1) reduction of wildlife-vehicle collisions and 2) restoration of landscape connectivity to facilitate wildlife movement across the roaded landscape. During our study, we assessed the effectiveness of the mitigation measures in reducing mule deer mortality in the following ways: 1) we compared the number of deer-vehicle collisions in the newly fenced area with a control area without fencing; 2) we analyzed the ‘end-of-the-fence’ problem, defined here as increased mortality of mule deer at the ends of the 2.4-m high exclusion fences; and 3) we evaluated the frequency of animal crossings of the new underpasses using remotely-sensed cameras and compared them with crossing frequency rates for a 20-year-old control underpass. We compared six years of pre-construction mortality (during 1998-2003) with two years of post-construction data on mortality (during 2005-2006) and found a 98.5% decline in deer mortalities in the treatment (i.e. fenced, jump-outs and underpasses) vs a 2.9% decline in the control (i.e. no fences, no jump-outs and no underpasses). We detected no end-of-the-fence problems related to deer mortality. Migratory movements during fall and spring were clearly reflected in the use of underpass. Overall results demonstrated that the mitigation strategy was effective and reduced the number of deer-vehicle accidents, while allowing wildlife movement across the landscape.

Identifying and prioritizing ungulate migration routes for landscape-level conservation

USGS Publications Warehouse

Sawyer, H.; Kauffman, M.J.; Nielson, R.M.; Horne, J.S.

2009-01-01

As habitat loss and fragmentation increase across ungulate ranges, identifying and prioritizing migration routes for conservation has taken on new urgency. Here we present a general framework using the Brownian bridge movement model (BBMM) that: (1) provides a probabilistic estimate of the migration routes of a sampled population, (2) distinguishes between route segments that function as stopover sites vs. those used primarily as movement corridors, and (3) prioritizes routes for conservation based upon the proportion of the sampled population that uses them. We applied this approach to a migratory mule deer (Odocoileus hemionus) population in a pristine area of southwest Wyoming, USA, where 2000 gas wells and 1609 km of pipelines and roads have been proposed for development. Our analysis clearly delineated where migration routes occurred relative to proposed development and provided guidance for on-the-ground conservation efforts. Mule deer migration routes were characterized by a series of stopover sites where deer spent most of their time, connected by movement corridors through which deer moved quickly. Our findings suggest management strategies that differentiate between stopover sites and movement corridors may be warranted. Because some migration routes were used by more mule deer than others, proportional level of use may provide a reasonable metric by which routes can be prioritized for conservation. The methods we outline should be applicable to a wide range of species that inhabit regions where migration routes are threatened or poorly understood. ?? 2009 by the Ecological Society of America.

Incidence of Burkholderia mallei infection among indigenous equines in India.

PubMed

Malik, Praveen; Singha, Harisankar; Goyal, Sachin K; Khurana, Sandip K; Tripathi, Badri Naryan; Dutt, Abha; Singh, Dabal; Sharma, Neeraj; Jain, Sanjay

2015-01-01

Burkholderia mallei is the causative agent of glanders which is a highly contagious and fatal disease of equines. Considering the nature and severity of the disease in equines, and potential of transmission to human beings, glanders is recognised as a 'notifiable' disease in many countries. An increasing number of glanders outbreaks throughout the Asian continents, including India, have been noticed recently. In view of the recent re-emergence of the disease, the present study was undertaken to estimate the prevalence of glanders among indigenous equines from different parts of India. Serum samples were analysed by complement fixation test (CFT) and ELISA for the detection of B mallei specific antibodies. A total of 7794 equines, which included 4720 horses, 1881 donkeys and 1193 mules were sampled from April 2011 to December 2014 from 10 states of India. Serologically, 36 equines (pony=7, mules=10, horses=19) were found to be positive for glanders by CFT and indirect-ELISA. The highest number of cases were detected in Uttar Pradesh (n=31) followed by Himachal Pradesh (n=4) and Chhattisgarh (n=1). Isolation of B mallei was attempted from nasal and abscess swabs collected from seropositive equines. Four isolates of B mallei were cultured from nasal swabs of two mules and two ponies. Identity of the isolates was confirmed by PCR and sequencing of fliP gene fragment. The study revealed circulation of B mallei in northern India and the need for continued surveillance to support the eradication.

Incidence of Burkholderia mallei infection among indigenous equines in India

PubMed Central

Malik, Praveen; Singha, Harisankar; Goyal, Sachin K; Khurana, Sandip K; Tripathi, Badri Naryan; Dutt, Abha; Singh, Dabal; Sharma, Neeraj; Jain, Sanjay

2015-01-01

Burkholderia mallei is the causative agent of glanders which is a highly contagious and fatal disease of equines. Considering the nature and severity of the disease in equines, and potential of transmission to human beings, glanders is recognised as a ‘notifiable’ disease in many countries. An increasing number of glanders outbreaks throughout the Asian continents, including India, have been noticed recently. In view of the recent re-emergence of the disease, the present study was undertaken to estimate the prevalence of glanders among indigenous equines from different parts of India. Serum samples were analysed by complement fixation test (CFT) and ELISA for the detection of B mallei specific antibodies. A total of 7794 equines, which included 4720 horses, 1881 donkeys and 1193 mules were sampled from April 2011 to December 2014 from 10 states of India. Serologically, 36 equines (pony=7, mules=10, horses=19) were found to be positive for glanders by CFT and indirect-ELISA. The highest number of cases were detected in Uttar Pradesh (n=31) followed by Himachal Pradesh (n=4) and Chhattisgarh (n=1). Isolation of B mallei was attempted from nasal and abscess swabs collected from seropositive equines. Four isolates of B mallei were cultured from nasal swabs of two mules and two ponies. Identity of the isolates was confirmed by PCR and sequencing of fliP gene fragment. The study revealed circulation of B mallei in northern India and the need for continued surveillance to support the eradication. PMID:26457190

CROSS TRANSMISSION OF 'GIARDIA'

EPA Science Inventory

Giardia cysts isolated from fecal samples obtained from humans (Homo sapiens), beaver (Castor canadensis), dogs (Canis familiaris), cats (Felis domesticus), bighorn X mouflon sheep (Ovis canadensis X O. musimon), guinea pig (Cavis porcellus), muskrat (Ondatra ziethica) and mule d...

3. Historic American Buildings Survey E. W. Russell, Photographer, June ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Historic American Buildings Survey E. W. Russell, Photographer, June 19, 1936 OLD MULE GIN HOUSE LOOKING S. E. - Cotton Gin & Well Sweep, Cliatt Plantation, State Route 165, Cottonton, Russell County, AL

1. Historic American Buildings Survey E. W. Russell, Photographer, June ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. Historic American Buildings Survey E. W. Russell, Photographer, June 19, 1936 OLD MULE GIN HOUSE LOOKING N. W. - Cotton Gin & Well Sweep, Cliatt Plantation, State Route 165, Cottonton, Russell County, AL

Evidence for de-sulfidation to form native electrum in the Fire Creek epithermal gold-silver deposit, north-central Nevada

NASA Astrophysics Data System (ADS)

Perez, J.; Day, J. M.; Cook, G. W.

2012-12-01

The Fire Creek property is a newly developed and previously unstudied epithermal Au-Ag deposit located in the Northern Shoshone range of north central Nevada. The mineralization occurs within and above en echelon N-NW trending basaltic dykes that are hosted within a co-genetic and bimodal suite of mid-Miocene basalts and andesites formed in association with the Yellowstone hotspot-track. Previous studies of Au-Ag mineralization in the Great Basin have focused primarily on extensively mined and/or low-grade deposits. Therefore, the ability for unrestricted sampling of a major Au-Ag deposit early in its exploration and development represents an opportunity for refined understanding of epithermal ore genesis processes. New petrology reveals at least two distinct pulses of mineralization that in relative order of timing are: 1) S-rich veins which are associated with initial host-rock alteration; 2) quartz- and/or calcite-rich veins which vary from fine-grained to lath-like quartz crystals with large calcite crystals in vein centers. Native electrum occurs only within the second phase of mineralization and typically occurs within quartz and adjacent to cross-cut first-phase S-rich veins. In places the electrum appears to replace or form overgrowths around existing sulfide phases. High levels of gold and silver are found in both the first (0.8 g Au/tonne) and second-phase pulses (37 g Au/tonne). Fire Creek shares many similarities with its northern neighbor, the Mule Canyon Au-Ag deposit, with high Fe sulfide contents for some of the ores, altered wall-rocks and the presence of narrow and discontinuous gold-bearing siliceous veins. Like Fire Creek, Mule Canyon possesses two distinct mineralizing phases, a sulfide rich and a late stage calcite/silica assemblage. The first pulse appears to be identical in both locations with a variation of disseminated to euhedral iron-sulfides and associated intense alteration of host rock. However, Fire Creek differs from Mule Canyon in that the second phase of mineralization shows spatial and petrographic association with coarser silica and carbon phases. Conversely associations of electrum in Mule Canyon are typically with chalcedony or opal veins and hydrothermal breccia matrices (John et al. Econ. Geol. 98, 425-463, 2003). Opal and chalcedony phases do not appear within fracture-filled veins in Fire Creek, but occur as cap rocks on the surface. These associations are likely driven by impingement of basaltic dikes into ground waters in both the Fire Creek and Mule Canyon deposits. However, in the case of Fire Creek, our study demonstrates that there is a clear spatial dependence between the electrum, primary S-rich mineralized veins and phases of coarse carbonate and silica. We postulate that this occurs through increased brecciation and sub-surface boiling of hydrothermal fluids leading to de-sulfidation and a marked change in alteration and mineral assemblage.

3. Photocopy of c. 1906 photograph looking E at water ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

3. Photocopy of c. 1906 photograph looking E at water tower showing corn grinding shed to the left and mule barn to the rear. - Laurel Valley Sugar Plantation, State Route 308, Thibodaux, Lafourche Parish, LA

29 CFR 780.120 - Raising of “livestock.”

Code of Federal Regulations, 2010 CFR

2010-07-01

..., mules, donkeys, and goats. It does not include such animals as albino and other rats, mice, guinea pigs... F. 2d 1), but employees employed in propagating or farming of fish may qualify for exemption under...

Pronghorn and Mule Deer Use of Underpasses and Overpasses Along US Highway 191, Wyoming

DOT National Transportation Integrated Search

2015-09-01

The seasonal migrations of ungulates are increasingly threatened by various forms of anthropogenic disturbance, including roads, fences, and other infrastructure. While roadway impacts (i.e., wildlifevehicle collisions and landscape permeability) ...

Psoroptic scabies

USGS Publications Warehouse

Lange, R.E.; Thorne, E. Tom; Kingston, Newton; Jolly, William R.; Bergstrom, Robert C.

1982-01-01

Scabies, caused by mites of the genus Psoroptes, is widespread in free-ranging desert bighorn sheet, Rocky Mountain bighorn sheep, elk, and white-tailed deer. It has been identified on captive mule deer and may have been present on bison.

Human land use influences chronic wasting disease prevalence in mule deer

USGS Publications Warehouse

Farnsworth, Matthew L.; Wolfe, L.L.; Hobbs, N.T.; Burnham, K.P.; Williams, E.S.; Theobald, D.M.; Conner, M.M.; Miller, M.W.

2005-01-01

Human alteration of landscapes can affect the distribution, abundance, and behavior of wildlife. We explored the effects of human land use on the prevalence of chronic wasting disease (CWD) in mule deer (Odocoileus hemionus) populations residing in north-central Colorado. We chose best approximating models estimating CWD prevalence in relation to differences in human land use, sex, and geographic location. Prevalence was higher in developed areas and among male deer, suggesting anthropogenic influences on the occurrence of disease. We also found a relatively high degree of variation in prevalence across the three study sites, suggesting that spatial patterns in disease may be influenced by other factors operating at a broader, landscape scale. Our results suggest that multiple factors, including changes in land use, differences in exposure risk between sexes, and landscape-scaled heterogeneity, are associated with CWD prevalence in north-central Colorado.

Mineral resources of the Fish Creek Canyon, Road Canyon, and Mule Canyon Wilderness Study Areas, San Juan County, Utah

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bove, D.J.; Shawe, D.R.; Lee, G.K.

1989-01-01

This book reports the Fish Creek Canyon (UT-060-204), Road Canyon(UT-060-201), and Mule Canyon (UT-060-205B) Wilderness Study Areas, which comprise 40,160 acres, 52,420 acres, and 5,990 acres, respectively, studied for their mineral endowment. A search of federal, state, and county records showed no current or previous mining-claim activity. No mineral resources were identified during field examination of the study areas. Sandstone and sand and gravel have no unique qualities but could have limited local use for road metal or other construction purposes. However, similar materials are abundant outside the study areas. The three study areas have moderate resource potential for undiscoveredmore » oil and gas and low resource potential for undiscovered metals, including uranium and thorium, coal, and geothermal energy.« less

Evidence of Bovine viral diarrhea virus Infection in Three Species of Sympatric Wild Ungulates in Nevada: Life History Strategies May Maintain Endemic Infections in Wild Populations

PubMed Central

Wolff, Peregrine L.; Schroeder, Cody; McAdoo, Caleb; Cox, Mike; Nelson, Danielle D.; Evermann, James F.; Ridpath, Julia F.

2016-01-01

Evidence for bovine viral diarrhea virus (BVDV) infection was detected in 2009–2010 while investigating a pneumonia die-off in Rocky Mountain bighorn sheep (Ovis canadensis, canadensis), and sympatric mountain goats (Oreamnos americanum) in adjacent mountain ranges in Elko County, Nevada. Seroprevalence to BVDV-1 was 81% (N = 32) in the bighorns and 100% (N = 3) in the mountain goats. Serosurveillance from 2011 to 2015 of surviving bighorns and mountain goats as well as sympatric mule deer (Odocoileus hemionus), indicated a prevalence of 72% (N = 45), 45% (N = 51), and 51% (N = 342) respectively. All species had antibody titers to BVDV1 and BVDV2. BVDV1 was isolated in cell culture from three bighorn sheep and a mountain goat kid. BVDV2 was isolated from two mule deer. Six deer (N = 96) sampled in 2013 were positive for BVDV by antigen-capture ELISA on a single ear notch. Wild ungulates and cattle concurrently graze public and private lands in these two mountain ranges, thus providing potential for interspecies viral transmission. Like cattle, mule deer, mountain goats, and bighorn sheep can be infected with BVDV and can develop clinical disease including immunosuppression. Winter migration patterns that increase densities and species interaction during the first and second trimester of gestation may contribute to the long term maintenance of the virus in these wild ungulates. More studies are needed to determine the population level impacts of BVDV infection on these three species. PMID:27014215

Dietary response of sympatric deer to fire using stable isotope analysis of liver tissue

USGS Publications Warehouse

Walter, W. David; Zimmerman, T.J.; Leslie, David M.; Jenks, J.A.

2009-01-01

Carbon (??13C) and nitrogen (??15N) isotopes in biological samples from large herbivores identify photosynthetic pathways (C3 vs. C4) of plants they consumed and can elucidate potential nutritional characteristics of dietary selection. Because large herbivores consume a diversity of forage types, ??13C and ??15N in their tissue can index ingested and assimilated diets through time. We assessed ??13C and ??15N in metabolically active liver tissue of sympatric mule deer (Odocoileus hemionus) and white-tailed deer (O. virginianus) to identify dietary disparity resulting from use of burned and unburned areas in a largely forested landscape. Interspecific variation in dietary disparity of deer was documented 2-3 years post-fire in response to lag-time effects of vegetative response to burning and seasonal (i.e., summer, winter) differences in forage type. Liver ??13C for mule deer were lower during winter and higher during summer 2 years post-fire on burned habitat compared to unburned habitat suggesting different forages were consumed by mule deer in response to fire. Liver ??15N for both species were higher on burned than unburned habitat during winter and summer suggesting deer consumed more nutritious forage on burned habitat during both seasons 2 and 3 years post-fire. Unlike traditional methods of dietary assessment that do not measure uptake of carbon and nitrogen from dietary components, analyses of stable isotopes in liver or similar tissue elucidated ??13C and ??15N assimilation from seasonal dietary components and resulting differences in the foraging ecology of sympatric species in response to fire.

Prevalence and persistence of Taylorella asinigenitalis in male donkeys.

PubMed

Donahue, James M; Timoney, Peter J; Carleton, Carla L; Marteniuk, Judy V; Sells, Stephen F; Meade, Barry J

2012-12-07

This study was undertaken to investigate the prevalence of Taylorella asinigenitalis in a subset of the donkey population of Michigan and in other equids on farms on which the organism was identified. Other aims were to further characterize the carrier state in terms of persistence and preferred sites of colonization of T. asinigenitalis in the male donkey as well as determine the genotype of any isolates of the organism. Initial testing of 43 donkeys and 1 mule turned up 4 (9.3%) donkeys culture positive for T. asinigenitalis. The 4 culture-positive donkeys resided on 2 farms accommodating a collective total of 89 equids, of which 23 (25.8%) were confirmed positive for T. asinigenitalis. The positive equid population on the 2 farms comprised 14 (67%) of 21 gelded donkeys, 8 (36.4%) of 22 intact male donkeys, and 1 (25%) of 4 gelded horses. T. asinigenitalis was not isolated from 27 female donkeys, 11 female horses, 2 female mules, 1 male horse, or 1 male mule resident on these premises. Isolations of the bacterium were obtained from a number of male donkeys whenever they were sampled over a span of 33 months; preferential sites of isolation were the urethral fossa (fossa glandis), dorsal diverticulum of the urethral sinus, and terminal urethra. Isolates of T. asinigenitalis from the 23 culture-positive equids comprised 2 genotypes, one identical to the type strain isolated in California in 1997, and the other identical to 2 strains isolated from donkey jacks in Kentucky in 1998. Copyright © 2012 Elsevier B.V. All rights reserved.

Modeling the relationships between quality and biochemical composition of fatty liver in mule ducks.

PubMed

Theron, L; Cullere, M; Bouillier-Oudot, M; Manse, H; Dalle Zotte, A; Molette, C; Fernandez, X; Vitezica, Z G

2012-09-01

The fatty liver of mule ducks (i.e., French "foie gras") is the most valuable product in duck production systems. Its quality is measured by the technological yield, which is the opposite of the fat loss during cooking. The purpose of this study was to determine whether biochemical measures of fatty liver could be used to accurately predict the technological yield (TY). Ninety-one male mule ducks were bred, overfed, and slaughtered under commercial conditions. Fatty liver weight (FLW) and biochemical variables, such as DM, lipid (LIP), and protein content (PROT), were collected. To evaluate evidence for nonlinear fat loss during cooking, we compared regression models describing linear and nonlinear relations between biochemical measures and TY. We detected significantly greater (P = 0.02) linear relation between DM and TY. Our results indicate that LIP and PROT follow a different pattern (linear) than DM and showed that LIP and PROT are nonexclusive contributing factors to TY. Other components, such as carbohydrates, other than those measured in this study, could contribute to DM. Stepwise regression for TY was performed. The traditional model with FLW was tested. The results showed that the weight of the liver is of limited value in the determination of fat loss during cooking (R(2) = 0.14). The most accurate TY prediction equation included DM (in linear and quadratic terms), FLW, and PROT (R(2) = 0.43). Biochemical measures in the fatty liver were more accurate predictors of TY than FLW. The model is useful in commercial conditions because DM, PROT, and FLW are noninvasive measures.

Modular assembly of transposable element arrays by microsatellite targeting in the guayule and rice genomes.

PubMed

Valdes Franco, José A; Wang, Yi; Huo, Naxin; Ponciano, Grisel; Colvin, Howard A; McMahan, Colleen M; Gu, Yong Q; Belknap, William R

2018-04-19

Guayule (Parthenium argentatum A. Gray) is a rubber-producing desert shrub native to Mexico and the United States. Guayule represents an alternative to Hevea brasiliensis as a source for commercial natural rubber. The efficient application of modern molecular/genetic tools to guayule improvement requires characterization of its genome. The 1.6 Gb guayule genome was sequenced, assembled and annotated. The final 1.5 Gb assembly, while fragmented (N 50  = 22 kb), maps > 95% of the shotgun reads and is essentially complete. Approximately 40,000 transcribed, protein encoding genes were annotated on the assembly. Further characterization of this genome revealed 15 families of small, microsatellite-associated, transposable elements (TEs) with unexpected chromosomal distribution profiles. These SaTar (Satellite Targeted) elements, which are non-autonomous Mu-like elements (MULEs), were frequently observed in multimeric linear arrays of unrelated individual elements within which no individual element is interrupted by another. This uniformly non-nested TE multimer architecture has not been previously described in either eukaryotic or prokaryotic genomes. Five families of similarly distributed non-autonomous MULEs (microsatellite associated, modularly assembled) were characterized in the rice genome. Families of TEs with similar structures and distribution profiles were identified in sorghum and citrus. The sequencing and assembly of the guayule genome provides a foundation for application of current crop improvement technologies to this plant. In addition, characterization of this genome revealed SaTar elements with distribution profiles unique among TEs. Satar targeting appears based on an alternative MULE recombination mechanism with the potential to impact gene evolution.

9 CFR 327.26 - Official import inspection marks and devices.

Code of Federal Regulations, 2010 CFR

2010-01-01

... horsemeat food products. EC11SE91.027 For application to mule and other (nonhorse) equine carcasses, primal parts, and cuts, not in containers. EC11SE91.028 For application to outside containers of equine meat...

Hyperelastosis in the Horse

USDA-ARS?s Scientific Manuscript database

Equine hyperelastosis cutis, also known as dermatosporaxis and Ehlers-Danlos Syndrome (HERDA), is an autosomal recessive inheritable disease and has been reported in Thoroughbreds, Morgans, Haflingers , Hanoverians, a Swiss Warmblood, a mule and several Arabian cross horses in the United Kingdom, U...

Wildlife accident reduction study and monitoring : Arizona State Route 64

DOT National Transportation Integrated Search

2012-11-01

"The research team assessed elk (Cervus elaphus), mule deer (Odocoileus hemionus), and pronghorn (Antilocapra : americana) movements and vehicle collision patterns from 2007 through 2009 along a 57 mi stretch of State Route : (SR) 64 to develop strat...

75 FR 22863 - Notice of Permit Applications Received Under the Antarctic Conservation Act of 1978 (Pub. L. 95-541)

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-30

.... Applicant: Stevem D. Emslie, Department of Biology and Marine Biology, University of North Carolina... Point, Anvers Island, Palmer Archipelago, ASPA 143-Marine Plain, Mule Peninsula, Vestfold Hills, ASPA...

DEVELOPMENT OF AN EMAT IN-LINE INSPECTION SYSTEM FOR DETECTION, DISCRIMINATION, AND GRADING OF STRESS CORROSION CRACKING IN PIPELINES

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jeff Aron; Jeff Jia; Bruce Vance

2005-02-01

This report describes prototypes, measurements, and results for a project to develop a prototype pipeline in-line inspection (ILI) tool that uses electromagnetic acoustic transducers (EMATs) to detect and grade stress corrosion cracking (SCC). The introduction briefly provides motivation and describes SCC, gives some background on EMATs and guided ultrasonic waves, and reviews promising results of a previous project using EMATs for SCC. The experimental section then describes lab measurement techniques and equipment, the lab mouse and prototypes for a mule, and scan measurements made on SCC. The mouse was a moveable and compact EMAT setup. The prototypes were even moremore » compact circuits intended to be pulled or used in an ILI tool. The purpose of the measurements was to determine the best modes, transduction, and processing to use, to characterize the transducers, and to prove EMATs and mule components could produce useful results. Next, the results section summarizes the measurements and describes the mouse scans, processing, prototype circuit operating parameters, and performance for SH0 scans. Results are given in terms of specifications--like SNR, power, insertion loss--and parametric curves--such as signal amplitude versus magnetic bias or standoff, reflection or transmission coefficients versus crack depth. Initially, lab results indicated magnetostrictive transducers using both SH0 and SV1 modes would be worthwhile to pursue in a practical ILI system. However, work with mule components showed that SV1 would be too dispersive, so SV1 was abandoned. The results showed that reflection measurements, when normalized by the direct arrival are sensitive to and correlated with SCC. This was not true for transmission measurements. Processing yields a high data reduction, almost 60 to 1, and permits A and C scan display techniques and software already in use for pipeline inspection. An analysis of actual SH0 scan results for SCC of known dimensions showed that length and depth could be determined for deep enough cracks. Defect shadow and short length effects were apparent but may be taken into account. The SH0 scan was done with the mule prototype circuits and permanent magnet EMATs. These gave good enough results that this hardware and the processing techniques are very encouraging for use in a practical ILI tool.« less

Deciphering mechanisms underlying the genetic variation of general production and liver quality traits in the overfed mule duck by pQTL analyses.

PubMed

François, Yoannah; Vignal, Alain; Molette, Caroline; Marty-Gasset, Nathalie; Davail, Stéphane; Liaubet, Laurence; Marie-Etancelin, Christel

2017-04-19

The aim of this study was to analyse the mechanisms that underlie phenotypic quantitative trait loci (QTL) in overfed mule ducks by identifying co-localized proteomic QTL (pQTL). The QTL design consisted of three families of common ducks that were progeny-tested by using 294 male mule ducks. This population of common ducks was genotyped using a genetic map that included 334 genetic markers located across 28 APL chromosomes (APL for Anas platyrhynchos). Mule ducks were phenotyped for 49 traits related to growth, metabolism, overfeeding ability and meat and fatty liver quality, and 326 soluble fatty liver proteins were quantified. One hundred and seventy-six pQTL and 80 phenotypic QTL were detected at the 5% chromosome-wide significance threshold. The great majority of the identified pQTL were trans-acting and localized on a chromosome other than that carrying the coding gene. The most significant pQTL (1% genome-wide significance) were found for alpha-enolase on APL18 and fatty acid synthase on APL24. Some proteins were associated with numerous pQTL (for example, 17 and 14 pQTL were detected for alpha-enolase and apolipoprotein A1, respectively) and pQTL hotspots were observed on some chromosomes (APL18, 24, 25 and 29). We detected 66 co-localized phenotypic QTL and pQTL for which the significance of the two-trait QTL (2t-QTL) analysis was higher than that of the strongest QTL using a single-trait approach. Among these, 16 2t-QTL were pleiotropic. For example, on APL15, melting rate and abundance of two alpha-enolase spots appeared to be impacted by a single locus that is involved in the glycolytic process. On APLZ, we identified a pleiotropic QTL that modified both the blood level of glucose at the beginning of the force-feeding period and the concentration of glutamate dehydrogenase, which, in humans, is involved in increased glucose absorption by the liver when the glutamate dehydrogenase 1 gene is mutated. We identified pleiotropic loci that affect metabolic pathways linked to glycolysis or lipogenesis, and in the end to fatty liver quality. Further investigation, via transcriptomics and metabolomics approaches, is required to confirm the biomarkers that were found to impact the genetic variability of these phenotypic traits.

Vector ecology of equine piroplasmosis

USDA-ARS?s Scientific Manuscript database

Equine piroplasmosis (EP) is a disease of equidae including horses, donkeys, mules and zebras caused by either of two protozoan parasites, Theileria equi or Babesia caballi. These parasites are biologically transmitted between hosts via tick-vectors and although they have inherent differences, they ...

4. Photocopy of c. 1906 photograph taken from top of ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

4. Photocopy of c. 1906 photograph taken from top of water tower looking E showing mule barn and yard; building adjacent to mill pond is not identified. - Laurel Valley Sugar Plantation, State Route 308, Thibodaux, Lafourche Parish, LA

Effectiveness of wildlife crossing structures to minimize traffic collisions with mule deer and other wildlife in Nevada.

DOT National Transportation Integrated Search

2015-04-15

Maintenance of movement corridors is a fundamental component of conservation of biological diversity, and is especially important for terrestrial species that migrate extended distances. Movement corridors for largebodied species present unusual c...

Artemisia tridenata seed bank densities following wildfires

USDA-ARS?s Scientific Manuscript database

Big sagebrush (Artemisia spp.) is a critical shrub to such sagebrush obligate species as sage grouse, (Centocercus urophasianus), mule deer (Odocoileus hemionus), and pygmy rabbit (Brachylagus idahoensis). Big sagebrush do not sprout after wildfires and big sagebrush seed is generally short-lived a...

Big sagebrush seed bank densities following wildfires

USDA-ARS?s Scientific Manuscript database

Big sagebrush (Artemisia spp.) is a critical shrub to many wildlife species including sage grouse (Centrocercus urophasianus), mule deer (Odocoileus hemionus), and pygmy rabbit (Brachylagus idahoensis). Big sagebrush is killed by wildfires and big sagebrush seed is generally short-lived and do not s...

Accumulation and elimination of polychlorinated dibenzo-p-dioxins and dibenzofurans in mule ducks.

PubMed

Wu, Ting-Wei; Lee, Jai-Wei; Liu, Hsueh-Yen; Lin, Wei-Hsiao; Chu, Chun-Yen; Lin, Sheng-Lun; Chang-Chien, Guo Ping; Yu, Chi

2014-11-01

In Taiwan, a food safety crisis involving a presence of high concentrations of dioxin residues in duck eggs occurred in 2004. The dioxin content in duck meat sampled from supermarkets was also reported to be substantially higher than in products from other farm animals. Despite increased awareness of the potential for contamination and exposure to dioxins, the accumulation and elimination of dioxins in ducks have not been well characterized. In the present study, mule ducks were fed capsules containing polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) for 14 days and the trial was continued for another 28 days without PCDD/Fs supplementation. Ducks were sacrificed on the 14th, 28th, and 42nd days from the beginning of administration and samples of abdominal fat, breast, and liver tissue were obtained. The concentrations of PCDD/Fs were analyzed in the samples to investigate their distribution and elimination in various duck tissues. The bioaccumulation of PCDD/Fs in ducks was found to be tissue-dependent. In the abdominal fat, the bioconcentration factor was negatively correlated with the degree of chlorination. Conversely, more chlorinated PCDD/Fs (hexa- or hepta-congeners) were associated with higher bioconcentration in the liver and breast tissue. In terms of the efficiency of PCDD/Fs elimination, the liver was found to be the fastest, followed by the breast and the abdominal fat. The clearance rate positively correlated with the degree of chlorination, as determined by comparing the apparent elimination rate constant (k) of PCDD/Fs in various tissues. Overall, lower k values observed in this study imply that mule ducks have a reduced clearance of PCDD/Fs in comparison with layer and broiler chickens. Copyright © 2014 Elsevier B.V. All rights reserved.

Regulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination

PubMed Central

Markkanen, Enni; van Loon, Barbara; Ferrari, Elena; Parsons, Jason L.; Dianov, Grigory L.; Hübscher, Ulrich

2012-01-01

It is of pivotal importance for genome stability that repair DNA polymerases (Pols), such as Pols λ and β, which all exhibit considerably reduced fidelity when replicating undamaged DNA, are tightly regulated, because their misregulation could lead to mutagenesis. Recently, we found that the correct repair of the abundant and highly miscoding oxidative DNA lesion 7,8-dihydro-8-oxo-2′-deoxyguanine (8-oxo-G) is performed by an accurate repair pathway that is coordinated by the MutY glycosylase homologue (MutYH) and Pol λ in vitro and in vivo. Pol λ is phosphorylated by Cdk2/cyclinA in late S and G2 phases of the cell cycle, promoting Pol λ stability by preventing it from being targeted for proteasomal degradation by ubiquitination. However, it has remained a mystery how the levels of Pol λ are controlled, how phosphorylation promotes its stability, and how the engagement of Pol λ in active repair complexes is coordinated. Here, we show that the E3 ligase Mule mediates the degradation of Pol λ and that the control of Pol λ levels by Mule has functional consequences for the ability of mammalian cells to deal with 8-oxo-G lesions. Furthermore, we demonstrate that phosphorylation of Pol λ by Cdk2/cyclinA counteracts its Mule-mediated degradation by promoting recruitment of Pol λ to chromatin into active 8-oxo-G repair complexes through an increase in Pol λ’s affinity to chromatin-bound MutYH. Finally, MutYH appears to promote the stability of Pol λ by binding it to chromatin. In contrast, Pol λ not engaged in active repair on chromatin is subject for proteasomal degradation. PMID:22203964

An analysis of human pathogens found in horse/mule manure along the John Muir Trail in Kings Canyon and Sequoia and Yosemite National Parks.

PubMed

Derlet, Robert Wayne; Carlson, James Reynolds

2002-01-01

To determine the prevalence of microorganisms that are potentially pathogenic for humans in horse/mule manure along the John Muir Trail (JMT). Random samples of horse/mule manure were collected along sections of the JMT in Yosemite, Kings Canyon, and Sequoia national parks (NP), as well as in portions of the Pacific Crest Trail (PCT) and selected JMT/PCT access trails. Convenience samples of wild animal scat found within I mile of trails were also collected. The fresh specimens were individually preserved both in 0.9% saline and polyvinyl alcohol (PVA)-containing tubes and stored at 4 degrees C until time of analysis. Bacteriological analysis was performed using standard microbiology laboratory procedures. PVA samples were stained with trichrome and were then examined by a parasitologist. Collection: A total of 186 trail miles were sampled, including 113 on the JMT (Yosemite 37, Kings 53, and Sequoia 23). The PCT samplings included 24 miles, and NP and wilderness area access trails added an additional 49 miles. A total of 102 samples were collected, which included 81 samples from pack animals and 21 identified as having come from wild animals. Pack Animal Bacteria: All plated specimens grew large numbers of commensal gut flora. Potential pathogenic bacteria were found in only 12 samples and included Hafnia alvei (4), Serratia odorifera (1), Citrobacter freundii (1), Escherichia vulneris (1), Clostridium clostridioforme (1), Yersinia enterocolitica (1), Sherwinella putraformus (1), and Enterobacter spp (4). No Escherichia coli O157, Salmonella, or Aeromonas were found. Microscopic examination for protozoal organisms revealed occasional commensal ciliates and I Giardia. Wild Animal Pathogens: One specimen grew Y enterocolitica, and another grew Enterobacter amnigenus. We found a low prevalence of human pathogens in pack animal manure on the JMT.

Diets and habitat analyses of mule deer on the 200 areas of the Hanford Site in southcentral Washington

DOE Office of Scientific and Technical Information (OSTI.GOV)

Uresk, D.W.; Uresk, V.A.

1980-10-01

Forty-four food items were identified in the fecal pellets of the mule deer (Odocoileus hemionus hemionus) on three areas of the Hanford Site. Microscopic analysis of plant fragments indicated that bitterbrush was the most common species occurring in the diets of deer from the B-C Cribs area. Russian thistle (Salsola kali) and goldenrod (Solidago sp.) were the most abundant plants found in the fecal pellets collected from B Pond and Gable Mountain Pond habitats, respectively. The similarity in diets among the habitats was low, ranging from 10% to 16%. Preference indices of forage plants among sites were not similar (7%more » to 19%). The B-C Cribs, B Pond and Gable Mountain Pond habitats were characterized for canopy cover and frequency of occurrence of plant species. Twelve species were sampled in the B-C Cribs and B Pond areas; 22 species were identified on the Gable Mountain site. The most commonly occurring plant was cheatgrass (Bromus tectorum) in all three sites. The similarity in frequency and canopy cover of plants was low among sites. Mule deer inhabiting the Hanford site can serve as a pathway for movement of radioactive material from low-level radioactive waste management areas to man. Maximum levels of /sup 137/Cs found in deer pellet groups collected from B Pond and Gable Mountain Pond areas were 100 pCi/g and 128 pCi/g, respectively. Background levels were reported at B-C Cribs area. Maximum /sup 90/Sr values found in deer pellets at B Pond were 107 pCi/g and 184 pCi/g at Gable Mountain Pond.« less

Scrotal cancer in the north-west of England, 1962-68

PubMed Central

Lee, W. R.; Alderson, M. R.; Downes, Jean E.

1972-01-01

Lee, W. R., Alderson, M. R., and Downes, J. E. (1972).Brit. J. industr. Med.,29, 188-195. Scrotal cancer in the north-west of England, 1962-68. During the seven years 1962 to 1968 there were 103 cases of scrotal cancer reported to the Manchester Regional Cancer Registry. It was possible to obtain reasonably full occupational histories concerning 89 of these cases either from the men themselves or from close relatives. Fifty-one had been mule spinners, 40 of whom had worked in no other industry with a hazard of scrotal cancer, but the other 11 had. Another 19 men had never been mule spinners but had worked in occupations with a recognized hazard of this condition. Of the remainder, 14 had worked in occupations with a possible risk, although perhaps not generally recognized as such, and in five no clear cause was apparent. Because of the small numbers, it was possible to compare the observed and expected incidences only in broad occupational groups and these showed a statistically significant excess (P<0·001) only in textile workers and unskilled workers. However, our findings, taken with those of earlier workers, suggest that further attention might be given to four other groups, namely, automatic lathe operators, road workers, dye workers, and chain makers. Cancer of the scrotum tends to be a disease of the elderly. In 42% of men (other than mule spinners) scrotal cancer developed after the men had passed the age of retirement and therefore too late for routine medical examination at the workplace to be of any value. Fifty of the men had died, but scrotal cancer was registered as the underlying cause in only 19 and appeared on the death certificate in a further four. PMID:5063206

The type localities of the mule deer, Odocoileus hemionus (Rafinesque, 1817), and the Kansas white-tailed deer, Odocoileus virginianus macrourus (Rafinesque, 1817), are not where we thought they were

USGS Publications Warehouse

Woodman, Neal

2013-01-01

Among the iconic mammals of the North American West is the mule deer (Odocoileus hemionus). This species and a western subspecies of the white-tailed deer (Odocoileus virginianus macrourus) were two of seven mammals originally named and described as new species in 1817 by Constantine S. Rafinesque. Rafinesque never saw the animals that he named. Instead, he followed the then-acceptable practice of basing his new species on animals characterized in another published work, in this case the putative journal of Charles Le Raye, a French Canadian fur trader who was said to have traversed the upper Missouri River region before the Lewis and Clark Expedition and whose journal described some of the wildlife in detail. Unlike the mule deer, whose existence has been established by generations of biologists, wildlife management professionals, and sportsmen, Le Raye and his journal have since been proven to be fraudulent. Because Rafinesque's names were published in accordance with the taxonomic conventions of his time, they remain available, but, based on the questionable source of his descriptions, the identities and type localities of the species must be viewed as unreliable. Fortunately, much of the Le Raye journal was derived from other, verifiable contemporary sources. In particular, the descriptions of the two deer were based on the published journal of Patrick Gass, a member of the Lewis and Clark Expedition. Using the Gass journal as the original source of Rafinesque's descriptions, the type localities for the two deer can be reliably placed in Lyman County, South Dakota.

Movement reveals scale dependence in habitat selection of a large ungulate

USGS Publications Warehouse

Northrup, Joseph; Anderson, Charles R.; Hooten, Mevin B.; Wittemyer, George

2016-01-01

Ecological processes operate across temporal and spatial scales. Anthropogenic disturbances impact these processes, but examinations of scale dependence in impacts are infrequent. Such examinations can provide important insight to wildlife–human interactions and guide management efforts to reduce impacts. We assessed spatiotemporal scale dependence in habitat selection of mule deer (Odocoileus hemionus) in the Piceance Basin of Colorado, USA, an area of ongoing natural gas development. We employed a newly developed animal movement method to assess habitat selection across scales defined using animal-centric spatiotemporal definitions ranging from the local (defined from five hour movements) to the broad (defined from weekly movements). We extended our analysis to examine variation in scale dependence between night and day and assess functional responses in habitat selection patterns relative to the density of anthropogenic features. Mule deer displayed scale invariance in the direction of their response to energy development features, avoiding well pads and the areas closest to roads at all scales, though with increasing strength of avoidance at coarser scales. Deer displayed scale-dependent responses to most other habitat features, including land cover type and habitat edges. Selection differed between night and day at the finest scales, but homogenized as scale increased. Deer displayed functional responses to development, with deer inhabiting the least developed ranges more strongly avoiding development relative to those with more development in their ranges. Energy development was a primary driver of habitat selection patterns in mule deer, structuring their behaviors across all scales examined. Stronger avoidance at coarser scales suggests that deer behaviorally mediated their interaction with development, but only to a degree. At higher development densities than seen in this area, such mediation may not be possible and thus maintenance of sufficient habitat with lower development densities will be a critical best management practice as development expands globally.

2. Historic American Buildings Survey Alex Bush, Photographer, December 29, ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

2. Historic American Buildings Survey Alex Bush, Photographer, December 29, 1934. REAR SHOWING COURT AND WELL HOUSE. Figures in photo (l to r): 'Old Dunk' (mule), 'Aunt Lizzie' Bryan (cook), Needham Bryan, unknown - Perrin-Willis House, County Road 19, Forkland, Greene County, AL

9 CFR 92.1 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... animal kingdom, except man, including: Cattle, sheep, goats, other ruminants, swine, horses, asses, mules... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Definitions. 92.1 Section 92.1 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE EXPORTATION...

Radioecology of natural systems in Colordao. Fourteenth annual progress report, May 1, 1975--July 31, 1976. [Pu diffusion in terrestrial ecosystems at Rocky Flats Plant

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whicker, F.W.

1976-08-01

This report summarizes project activities during the period May 1, 1975 through July 31, 1976. The major study on the distribution and levels of Pu in major components of the terrestrial ecosystem at Rocky Flats was completed. Supportive studies on the ecology and pathology of small mammals and their role in Pu transport were essentially completed as well. Detailed studies on mule deer food habits, population dynamics, and movements at Rocky Flats are progressing. These studies are designed to measure the potential of mule deer in transporting Pu to uncontrolled areas. Alpha autoradiographic studies designed to measure Pu particle sizemore » and distribution and spatial patterns in soil were initiated. Field and greenhouse transport pathways from soil to vegetation are in progress and some early results reported. The status of studies on seasonal kinetics of Cs in a montane lake and stable lead geochemistry in an alpine lake watershed are also reported.« less

Compensatory mortality in mule deer populations: Technical progress report. [Odocoileus hemionus

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G.C.

1987-07-15

The hypothesis of compensatory mortality is critical to understanding population dynamics of wildlife species. This research tested for compensatory mortality in the juvenile (fawn) portion of a mule deer population. In the fall of 1986, 60 fawns were telemetered on both the control and treatment sites of the Little Hills study area. Thirteen adult females also were telemetered which, together with 31 telemetered adults already present, brought the total instrumented population to 164 at the onset of winter. Experimental manipulation to test for compensation in the population was successful, with 18% of the population on the treatment area (328 animals)more » removed. Line transect estimates of deer groups/ha were 0.12 +- 0.030 (D +- SE) for the control area and 0.14 +- 0.028 for the treatment area, giving 1727 individuals on the control area and 1490 on the treatment area. Thus the number of deer was measurably decreased on the treatment area by the removal operation.« less

Constraints on the tectonics of the Mule Mountains thrust system, southeast California and southwest Arizona

USGS Publications Warehouse

Tosdal, R.M.

1990-01-01

The Mule Mountains thrust system crops out discontinuously over a 100-km-strike length in this Blythe-Quartzsite region. Along the thrust system, middle and upper crustal metamorphic and plutonic rocks of Proterozoic and Mesozoic age are thrust N-NE (015??-035??) over a lower plate metamorphic terrane. Stratigraphic, petrologic, and Pb isotopic ties for Jurassic granitoids and for Jurassic(?) and Cretaceous sedimentary rocks across the various parts of the thrust system indicate that related crustal blocks are superposed and preclude it from having large displacements. Deformation occurred under low greenschist facies metamorphic conditions in the upper crust. Movement along the thrust system was probably limited to no more than a few tens of kilometers and occurred between 79??2 Ma and 70??4 Ma. Results suggest that the thrust system forms the southern boundary of the narow zone of Cretaceous intracratonic deformation, and it is one of the last tectonic events in the zone prior to regional cooling. -from Author

Effect of liquid nitrogen pre-treatment on various types of wool waste fibres for biogas production.

PubMed

Kuzmanova, Elena; Zhelev, Nikolai; Akunna, Joseph C

2018-05-01

This study investigated the role of liquid nitrogen (LN 2 ) in increasing microbial accessibility of wool proteins for biogas production. It involves a mechanical size reduction of four different types of raw wool fibres, namely, Blackface, Bluefaced Leicester, Texel and Scotch Mule, in presence of liquid nitrogen, followed by the determination of the methane production potential of the pre-treated wool fibres. The highest methane yield, 157.3 cm 3 g -1 VS, was obtained from pre-treated Scotch mule wool fibre culture, and represented more than 80% increase when compared to the yield obtained from its raw equivalent culture. The increase in biogas yield was attributed to the effectiveness of LN 2 in enhancing particle size reduction and the consequent increase in wool solubility and bioavailability. Results also showed that LN 2 pre-treatment can enhance size reduction but has limited effect on the molecular structure. The study also showed that the biogas potential of waste wool fibres varies with the type and source of wool.

Planning-Support for Mitigation of Wildlife-Vehicle Collisions and Highway Impacts on Migration Routes in Wyoming

DOT National Transportation Integrated Search

2016-08-23

Wyoming is home to abundant big game, including long-distance migratory species such as mule deer, elk, and pronghorn. Where these animals movement patterns intersect with roads, vehicles often hit animals. This poses a threat both to highway safe...

1. GENERAL VIEW OF OUTBUILDINGS, FROM BACK TO FOREGROUND IS ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. GENERAL VIEW OF OUTBUILDINGS, FROM BACK TO FOREGROUND IS THE CORN CRIB, PART OF A HOG PEN SEEN PAST THE BARN, THE BARN AND ATTACHED MULE SHED AND A MEAT HOUSE - Coffren House, Barn-Shed, 10007 Croom Road, Croom, Prince George's County, MD

Association analysis of PRNP gene region with chronic wasting disease in Rocky Mountain elk

USDA-ARS?s Scientific Manuscript database

Background: Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) of cervids including whitetail (Odocoileus virginianus) and mule deer (Odocoileus hemionus), Rocky Mountain elk (Cervus elaphus nelsoni), and moose (Alces alces). A leucine variant at position 132 (132L) in...

Using integration technology as a strategic advantage.

PubMed

Fry, P A

1993-08-01

The underlying premise of the Managed Competition Act previously cited is that through managed competition providers will be forced to lower care costs while increasing the level of positive care outcomes. Because it may also be that tomorrow's hospitals will find a severe rationing of technology, what can they do to prepare? Most of the systems in place today already have built within them all the necessary potential to address this premise and technology requirement with no change, no conversion, no expense for new equipment and software, and no disruption in day-to-day operations, just a little re-engineering. Today, however, these systems are similar to a 20-mule team pulling in different directions: all the power is there, but the wagon remains motionless and totally unable to reach its objective. It takes a skilled wagonmaster to bring them together, to make the mules work as a cohesive unit, to make the power of 20 mules greater than the sum of 20 mules. So it is and will be for the hospital of tomorrow. System integration is no longer a question of whether but of when. Those hospitals that use it today as a strategic advantage will be in a better position tomorrow to use it as a competitive strategic advantage in an environment that will reward low cost and high positive care outcomes and will penalize those that cannot compete. The technology is already here and economically within reach of nearly every hospital, just waiting to be used. The question that must nag all of us who want to make the health care system of America better is, Why not make the when now? Rich Helppie, president of Superior Consultant Company, summarized the solution well: The old ways will not give way to the new overnight. The re-engineering process in healthcare must evolve. Compared to the last 20 years, however, such evolution may appear to be a massive, forthright, complete, comprehensive, drastic and rapid revolution. Survival is the name of the game, and for healthcare organizations to survive, they must join the re-engineering revolution. When that happens, the "Americanized" health care system might look like the community network shown in Figure 7, which is a networked integration of all the systems used in the community working together and exchanging information, with hospitals exchanging information with other hospitals and sharing it with physicians, clinics, laboratories, radiology centers, universities, employers, payors, and governmental agencies.(ABSTRACT TRUNCATED AT 400 WORDS)

Experimental oral transmission of chronic wasting disease to reindeer (Rangifer tarandus tarandus)

USDA-ARS?s Scientific Manuscript database

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy or TSE of wild and farmed cervid ruminants in the North America, including white tailed, black tailed and mule deer, Rocky Mountain elk and Shira's moose. CWD, like the other TSEs, is associated with accumulation of an abnorm...

The Starkey project: history, facilities, and data collection methods for ungulate research.

Treesearch

Mary M. Rowland; Larry D. Bryant; Bruce K. Johnson; James H. Noyes; Michael J. Wisdom; Jack Ward Thomas

1997-01-01

In the 1980s resource managers were increasingly concerned about effects of timber harvest on ungulates in National Forests. Land and resource management plans incorporated restrictions on timber harvest to maintain cover for Rocky Mountain elk (Cervus elaphus nelsoni V. Bailey) and mule deer (Odocoileus hemionus...

Has the Starkey Project delivered on its commitments?

Treesearch

Jack Ward Thomas; Michael J. Wisdom

2004-01-01

The Starkey Project was conceived from intense debate about how best to manage habitats and populations of mule deer (Odocoileus hemionus) and elk (Cervus elaphus) in western North America (Rowland et al. 1997). Founders of the research effort promised to provide definitive knowledge about effects of the dominant public land...

12 CFR 32.3 - Lending limits.

Code of Federal Regulations, 2014 CFR

2014-01-01

... association's combined general limit. For purposes of this subsection, the term “livestock” includes dairy and beef cattle, hogs, sheep, goats, horses, mules, poultry and fish, whether or not held for resale. (ii... does not meet the requirements of the exception. (4) Loans secured by dairy cattle. A national bank's...

12 CFR 32.3 - Lending limits.

Code of Federal Regulations, 2012 CFR

2012-01-01

... “livestock” includes dairy and beef cattle, hogs, sheep, goats, horses, mules, poultry and fish, whether or... resulting lien does not meet the requirements of the exception. (4) Loans secured by dairy cattle. A... dairy cattle of paper given in payment for the cattle may not exceed 10 percent of the bank's capital...

12 CFR 32.3 - Lending limits.

Code of Federal Regulations, 2013 CFR

2013-01-01

... association's combined general limit. For purposes of this subsection, the term “livestock” includes dairy and beef cattle, hogs, sheep, goats, horses, mules, poultry and fish, whether or not held for resale. (ii... does not meet the requirements of the exception. (4) Loans secured by dairy cattle. A national bank's...

12 CFR 32.3 - Lending limits.

Code of Federal Regulations, 2011 CFR

2011-01-01

... “livestock” includes dairy and beef cattle, hogs, sheep, goats, horses, mules, poultry and fish, whether or... resulting lien does not meet the requirements of the exception. (4) Loans secured by dairy cattle. A... dairy cattle of paper given in payment for the cattle may not exceed 10 percent of the bank's capital...

KSC-02pd0103

NASA Image and Video Library

2002-01-29

KENNEDY SPACE CENTER, FLA. -- Workers in the Vertical Processing Facility get the Large Orbital Protective Enclosure (LOPE) ready to move to the Multi-Use Lightweight Equipment (MULE) carrier. The LOPE contains part of the payload on the Hubble Space Telescope Servicing Mission, STS-109, scheduled to launch Feb. 28 from Launch Pad 39A

The effects of downy brome invasion on mule deer habitat

USDA-ARS?s Scientific Manuscript database

Downy brome (Bromus tectorum), also widely known as cheatgrass, is a highly invasive exotic weed that has spread over millions of hectares of rangelands throughout the Intermountain West. Native to Eurasia, this early maturing annual provides a fine textured fuel that increases the chance, rate, sea...

Detection and impact of BVDV in wild ruminants

USDA-ARS?s Scientific Manuscript database

While BVDV is most commonly associated with cattle there is evidence, based on virus isolation and/or serology, that BVDV replicates in a wide variety of domesticated and wild ruminants including cervidae such as white tail deer, mule deer, fallow deer, elk, red deer, roe deer, and mousedeer and cap...

The Public Trustee: Ostrich, Mule or Owl?

ERIC Educational Resources Information Center

Pittenger, John C.

The role of state college trustees and their interaction with state government are considered. It is suggested that the trustee should be concerned about what is best for postsecondary education in the state generally as well as for the specific institution. The future trends indicate declining college enrollments, which require planning…

Wild ungulate herbivory suppresses deciduous woody plant establishment following salmonid stream restoration

Treesearch

Joshua P. Averett; Bryan A. Endress; Mary M. Rowland; Bridgett J. Naylor; Michael J. Wisdom

2017-01-01

Domestic and wild ungulates can exert strong influences on riparian woody vegetation establishment, yet little is known about how wild ungulate herbivory affects riparian restoration in the absence of cattle. We evaluated elk (Cervus elaphus) and mule deer (Odocoileus hemionus) impacts on the establishment of deciduous woody...

KSC-02pd0102

NASA Image and Video Library

2002-01-29

KENNEDY SPACE CENTER, FLA. -- Workers in the Vertical Processing Facility get the Large Orbital Protective Enclosure (LOPE) ready to move to the Multi-Use Lightweight Equipment (MULE) carrier. The LOPE contains part of the payload on the Hubble Space Telescope Servicing Mission, STS-109, scheduled to launch Feb. 28 from Launch Pad 39A

KSC-02pd0101

NASA Image and Video Library

2002-01-29

KENNEDY SPACE CENTER, FLA. -- Workers in the Vertical Processing Facility get the Large Orbital Protective Enclosure (LOPE) ready to move to the Multi-Use Lightweight Equipment (MULE) carrier. The LOPE contains part of the payload on the Hubble Space Telescope Servicing Mission, STS-109, scheduled to launch Feb. 28 from Launch Pad 39A

9 CFR 313.15 - Mechanical; captive bolt.

Code of Federal Regulations, 2010 CFR

2010-01-01

... slaughtering of sheep, swine, goats, calves, cattle, horses, mules, and other equines by using captive bolt... regard to kind, breed, size, age, and sex of the animal to produce the desired results. (2) Special... varies, depending on kind, breed, size, age, and sex of the animal. Young swine, lambs, and calves...

9 CFR 313.15 - Mechanical; captive bolt.

Code of Federal Regulations, 2011 CFR

2011-01-01

... slaughtering of sheep, swine, goats, calves, cattle, horses, mules, and other equines by using captive bolt... regard to kind, breed, size, age, and sex of the animal to produce the desired results. (2) Special... varies, depending on kind, breed, size, age, and sex of the animal. Young swine, lambs, and calves...

Techniques to construct New Zealand elk-proof fence.

Treesearch

Larry D. Bryant; Jack W. Thomas; Mary M. Rowland

1993-01-01

An elk-proof fence was built in 1987 at the Starkey Experimental Forest and Range in northeast Oregon. The 25,000-acre research enclosure holds several hundred Rocky Mountain elk (Cervus elaphus nelsoni V. Bailey) and Rocky Mountain mule deer (Odocoileus hemionus hemionus Rafinesque) year round. The fence, constructed with high...

The Starkey habitat database for ungulate research: construction, documentation, and use.

Treesearch

Mary M. Rowland; Priscilla K. Coe; Rosemary J. Stussy; [and others].

1998-01-01

The Starkey Project, a large-scale, multidisciplinary research venture, began in 1987 in the Starkey Experimental Forest and Range in northeast Oregon. Researchers are studying effects of forest management on interactions and habitat use of mule deer (Odocoileus hemionus hemionus), elk (Cervus elaphus nelsoni), and cattle. A...

9 CFR 351.2 - Terms defined.

Code of Federal Regulations, 2011 CFR

2011-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Definitions § 351.2 Terms defined. When used in..., horses, mules and other equines. (k) Technical animal fat means animal fat eligible for exportation, or storage for exportation, in accordance with § 325.11 of this chapter. (l) Certified technical animal fat...

9 CFR 351.2 - Terms defined.

Code of Federal Regulations, 2012 CFR

2012-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Definitions § 351.2 Terms defined. When used in..., horses, mules and other equines. (k) Technical animal fat means animal fat eligible for exportation, or storage for exportation, in accordance with § 325.11 of this chapter. (l) Certified technical animal fat...

9 CFR 351.2 - Terms defined.

Code of Federal Regulations, 2013 CFR

2013-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Definitions § 351.2 Terms defined. When used in..., horses, mules and other equines. (k) Technical animal fat means animal fat eligible for exportation, or storage for exportation, in accordance with § 325.11 of this chapter. (l) Certified technical animal fat...

9 CFR 351.2 - Terms defined.

Code of Federal Regulations, 2014 CFR

2014-01-01

... CERTIFICATION CERTIFICATION OF TECHNICAL ANIMAL FATS FOR EXPORT Definitions § 351.2 Terms defined. When used in..., horses, mules and other equines. (k) Technical animal fat means animal fat eligible for exportation, or storage for exportation, in accordance with § 325.11 of this chapter. (l) Certified technical animal fat...

[Equine recurrent uveitis].

PubMed

Spiess, B M

1997-01-01

Equine recurrent uveitis is an important ocular disease and the most common cause for blindness in horses and mules worldwide. The anatomy, physiology, immunology and inflammatory reactions of the uveal tract are discussed. Possible etiologies and the clinical signs are described. A detailed description of possible therapies is given and the prognosis is discussed.

Multimodal Sensor Fusion for Personnel Detection

DTIC Science & Technology

2011-07-01

video ). Efficacy of UGS systems is often limited by high false alarm rates because the onboard data processing algorithms may not be able to correctly...humans) and animals (e.g., donkeys , mules, and horses). The humans walked alone and in groups with and without backpacks; the animals were led by their

A Common Parvovirus in Deer from California, USA.

PubMed

Li, Linlin; Woods, Leslie; Gerstenberg, Greg; Deng, Xutao; Delwart, Eric

2016-10-01

We characterize the genome of the first reported deer parvovirus, Ungulate tetraparvovirus 5, which we detected by PCR in multiple tissues from 2/9 California mule deer ( Odocoileus hemionus californicus) with hair loss syndrome (HLS) and in 4/12 deer without HLS, suggesting this common infection does not cause HLS.

Chronic Wasting Disease Prions in Elk Antler Velvet

USDA-ARS?s Scientific Manuscript database

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy or prion disease of captive and free ranging white tailed deer, mule deer, Rocky Mountain elk and moose in the some parts of the United States and Canada. The presence of the disease has sharply curtailed movement of captive...

Immunization with synthetic peptide vaccine fails to protect mule deer (Odocoileus hemionus) from chronic wasting disease

USDA-ARS?s Scientific Manuscript database

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy of deer and elk. The disorder is characterized by accumulation of an abnormally folded isoform of the normal cellular prion protein. Disease prevalence in farmed herds of white tailed deer can exceed 80%. Attempts to control ...

Forty Acres and a Mule: A Critical Audit of California's "Williams" Legislation Implementation and the Implications for Educational Leaders

ERIC Educational Resources Information Center

Vang, Maiyoua

2012-01-01

This study investigated educational leaders' critical evaluations of California's landmark contemporary school equity legislation "Williams v. the State of California". Qualitative interview analysis indicated that leaders perceived the equity measure to be necessary but insufficient in advancing the larger project of educational…

Protocols for care and handling of deer and elk at the Starkey Experimental Forest and Range.

Treesearch

Michael J. Wisdom; John G. Cook; Mary M. Rowland; James H. Noyes

1993-01-01

Several hundred Rocky Mountain elk (Cervus elaphus nelsoni V. Bailey) and Rocky Mountain mule deer (Odocoileus hemionus hemionus Rafinesque) inhabit a fenced, 25,000-acre enclosure at the Starkey Experimental Forest and Range in the Blue Mountains of northeast Oregon. Research there requires handling...

Army Sustainment. Volume 43, Issue 2. March-April 2011

DTIC Science & Technology

2011-04-01

the night before. Barker notes, “Like the men, the animals were nearly mad with thirst,” and consequentially “a number of mules made a dash for the...5-month siege. The majority of these cap- tives died of starvation, exhaustion, disease, or cruelty by their Turkish captors. The fall of Kut

Mountain Goats (Oreamnos americanum) at the livestock/wildlife interface: A susceptible species

USDA-ARS?s Scientific Manuscript database

Mountain goats (Oreamnos americanum) were first introduced into the East Humboldt and Ruby Mountains of Elko County, Nevada in the 1960’s. These contiguous mountain ranges are also home to introduced Rocky Mountain bighorn sheep and native mule deer and are surrounded by both public and private rang...

Still No 40 Acres, Still No Mule

ERIC Educational Resources Information Center

Keels, Crystal L.

2005-01-01

The simple mention of reparations for African-Americans in the United States can be counted on to generate a firestorm. When it comes to the issue of recompense for injustices Black Americans have suffered throughout U.S. history--slavery, Jim Crow segregation, and other political and social mechanisms designed to maintain racial inequality--the…

How does targeted grazing with small ruminants influence subsequent patch use by mule deer and cattle?

USDA-ARS?s Scientific Manuscript database

Targeted grazing with small ruminants has been suggested as a means to control one-seed juniper encroachment (Juniperus monosperma Englem. Sarg) and enhance habitat for livestock and wildlife. We determined the short term influence of a localized targeted grazing treatment with goats and sheep cond...

Uncovering Teacher Leadership

ERIC Educational Resources Information Center

Ackerman, Richard; Mackenzie, Sarah V.

2006-01-01

Teacher leaders are the pack mules of effective school improvement because they carry the weight of responsibility for ensuring that reforms take root in the classroom and deepen the learning of all students. They continually think about the gap in schools between the real and the ideal, and the discrepancies that they witness compel them to push…

The New Frontier: Conquering the World Wide Web by Mule.

ERIC Educational Resources Information Center

Gresham, Morgan

1999-01-01

Examines effects of teaching hypertext markup language on students' perceptions of class goals in a networked composition classroom. Suggests sending documents via file transfer protocol by command line and viewing the Web with a textual browser shifted emphasis from writing to coding. Argues that helping students identify a balance between…

Weathered antlers as a source of DNA

Treesearch

Roy G. Lopez; Paul Beier

2012-01-01

We tested antlers of Coues white-tailed (Odocoileus virginianus couesi) and mule deer (O. hemionus) in various stages of natural decomposition to determine the degree of weathering that cast antlers could endure and still yield usable DNA. Based on physical characteristics, we partitioned antlers into 7 weathering categories ranging from freshly cast (class 1) to...

Animal Diseases Caused by Orbiviruses, Algeria

PubMed Central

Madani, Hafsa; Casal, Jordi; Alba, Anna; Allepuz, Alberto; Cêtre-Sossah, Catherine; Hafsi, Leila; Kount-Chareb, Houria; Bouayed-Chaouach, Nadera; Saadaoui, Hassiba

2011-01-01

Antibodies against bluetongue virus were detected in cattle, sheep, goats, and camels in Algeria in 2008. Antibodies against epizootic hemorrhagic disease virus were detected in cattle, but antibodies against African horse sickness virus were not detected in horses and mules. Epizootic hemorrhagic disease in northern Africa poses a major risk for the European Union. PMID:22172371

Modification of mixed-conifer forests by ruminant herbivores in the Blue Mountains ecological province.

Treesearch

Robert A. Riggs; Arthur R. Tiedemann; John G. Cook; et al.

2000-01-01

Secondary plant succession and the accumulation of biomass and nutrients were documented at seven ruminant exclosures in Abies and Pseudotsuga forests variously disturbed by logging, burning, and grass seeding. Long-term (25 or more years) foraging by Rocky Mountain mule deer (Odocoileus hemionus) and Rocky Mountain elk (Cervus elaphus...

Shrub-steppe vegetation trend, Middle Fork Salmon River, Idaho

Treesearch

James M. Peek

2000-01-01

The Middle Fork Salmon River drainage of the Frank Church River-Of-No-Return Wilderness has a history of livetock grazing from 1890 to 1950, and changes in grazing pressure from native ungulates. High mule deer (Odocoileus hemionus) populations occurred between 1940 and 1960, and high elk (Cervus elaphus) populations occurred in...

Utilization and cost for animal logging operations

Treesearch

Suraj P. Shrestha; Bobby L. Lanford

2001-01-01

Forest harvesting with animals is a labor-intensive operation. Due to the development of efficient machines and high volume demands from the forest products industry, mechanization of logging developed very fast, leaving behind the traditional horse and mule logging. It is expensive to use machines on smaller woodlots, which require frequent moves if mechanically...

Ungulate ecology of ponderosa pine ecosystems in the northwest

Treesearch

Martin Vavra; Kenric Walburger; Timothy DelCurto

2005-01-01

Ponderosa pine ecosystems provide important foraging habitats for both wild and domestic ungulates. Livestock typically graze ponderosa pine ecosystems from May through October. Mule deer and elk may utilize these habitats on a yearlong basis in some areas. Stand density has a significant effect on understory production. Competition for soil moisture and nitrogen limit...

25 CFR 161.207 - What livestock are authorized to graze?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 1 2010-04-01 2010-04-01 false What livestock are authorized to graze? 161.207 Section... LANDS GRAZING PERMITS General Provisions § 161.207 What livestock are authorized to graze? The following livestock are authorized to graze on the Navajo Partitioned Lands: horses, cattle, sheep, goats, mules...

50 CFR 32.20 - Alabama.

Code of Federal Regulations, 2014 CFR

2014-10-01

... hunting. One adult may supervise no more than two youth hunters. 4. We prohibit the use of horses, mules... #4 shot or smaller (see § 32.2(k)), rifles and handguns using rim-fire ammunition only, or archery... licensed and permitted adult 21 years of age or older, and must remain with the adult while hunting. One...

The Fort Valley Experimental Forest, ponderosa pine, and wildlife habitat research

Treesearch

David R. Patton

2008-01-01

Wildlife research at the Fort Valley Experimental Forest began with studies to determine how to control damage by wildlife and livestock to ponderosa pine (Pinus ponderosa) reproduction and tree growth. Studies on birds, small mammals, and mule deer (Odocoileus hemionus) browsing were initiated in the early 1930s and 1940s but...

Learning Qualitative and Quantitative Reasoning in a Microworld for Elastic Impacts.

ERIC Educational Resources Information Center

Ploetzner, Rolf; And Others

1990-01-01

Discusses the artificial-intelligence-based microworld DiBi and MULEDS, a multilevel diagnosis system. Developed to adapt tutoring style to the individual learner. Explains that DiBi sets up a learning environment, and simulates elastic impacts as a subtopic of classical mechanics, and supporting reasoning on different levels of mental domain…

9 CFR 75.1-75.3 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-01-01

... 9 Animals and Animal Products 1 2014-01-01 2014-01-01 false [Reserved] 75.1-75.3 Section 75.1-75.3 Animals and Animal Products ANIMAL AND PLANT HEALTH INSPECTION SERVICE, DEPARTMENT OF AGRICULTURE..., ASSES, PONIES, MULES, AND ZEBRAS Dourine in Horses and Asses §§ 75.1-75.3 [Reserved] Equine Infectious...

Integrating livestock production and wildlife in a sagebrush-grass ecosystem

Treesearch

Michael L. Wolfe; Gregg E. Simonds; Rick Danvir; William J. Hopkin

1996-01-01

Management of a 775-km2, privately-owned ranch in northeastern Utah exemplifies a progressive approach to utilizing domestic livestock and wild ungulates, elk (Cervus elaphus), mule deer (Odocoileus hemionus), and pronghorn (Antilocapra americana), for economic return while maintaining or enhancing land health. The management program on the Deseret Ranch includes the...

Detached and Unsustainable: Central Tensions in Teacher Research Capstones and the Possibilities for Reimagined Inquiry

ERIC Educational Resources Information Center

Fulmer, Ellie Fitts; Bodner, Jill

2017-01-01

With increased frequency, teacher education programs require candidates to engage in practice-based research capstones (e.g., Lattimer, 2012; Mule, 2006). Yet, experience provides evidence that newly credentialed teachers regularly disregard the practice of teacher inquiry immediately after graduation, prompting the authors to ask, "how can…

Mobilization of a plant transposon by expression of the transposon-encoded anti-silencing factor.

PubMed

Fu, Yu; Kawabe, Akira; Etcheverry, Mathilde; Ito, Tasuku; Toyoda, Atsushi; Fujiyama, Asao; Colot, Vincent; Tarutani, Yoshiaki; Kakutani, Tetsuji

2013-08-28

Transposable elements (TEs) have a major impact on genome evolution, but they are potentially deleterious, and most of them are silenced by epigenetic mechanisms, such as DNA methylation. Here, we report the characterization of a TE encoding an activity to counteract epigenetic silencing by the host. In Arabidopsis thaliana, we identified a mobile copy of the Mutator-like element (MULE) with degenerated terminal inverted repeats (TIRs). This TE, named Hiun (Hi), is silent in wild-type plants, but it transposes when DNA methylation is abolished. When a Hi transgene was introduced into the wild-type background, it induced excision of the endogenous Hi copy, suggesting that Hi is the autonomously mobile copy. In addition, the transgene induced loss of DNA methylation and transcriptional activation of the endogenous Hi. Most importantly, the trans-activation of Hi depends on a Hi-encoded protein different from the conserved transposase. Proteins related to this anti-silencing factor, which we named VANC, are widespread in the non-TIR MULEs and may have contributed to the recent success of these TEs in natural Arabidopsis populations.

Bayesian Modeling of Prion Disease Dynamics in Mule Deer Using Population Monitoring and Capture-Recapture Data

PubMed Central

Geremia, Chris; Miller, Michael W.; Hoeting, Jennifer A.; Antolin, Michael F.; Hobbs, N. Thompson

2015-01-01

Epidemics of chronic wasting disease (CWD) of North American Cervidae have potential to harm ecosystems and economies. We studied a migratory population of mule deer (Odocoileus hemionus) affected by CWD for at least three decades using a Bayesian framework to integrate matrix population and disease models with long-term monitoring data and detailed process-level studies. We hypothesized CWD prevalence would be stable or increase between two observation periods during the late 1990s and after 2010, with higher CWD prevalence making deer population decline more likely. The weight of evidence suggested a reduction in the CWD outbreak over time, perhaps in response to intervening harvest-mediated population reductions. Disease effects on deer population growth under current conditions were subtle with a 72% chance that CWD depressed population growth. With CWD, we forecasted a growth rate near one and largely stable deer population. Disease effects appear to be moderated by timing of infection, prolonged disease course, and locally variable infection. Long-term outcomes will depend heavily on whether current conditions hold and high prevalence remains a localized phenomenon. PMID:26509806

Intracerebral Malignant Plasmacytoma in a Mule Deer (Odocoileus hemionus).

PubMed

Clancy, C S; Roug, A; Armien, A G; Van Wettere, A J

2016-01-01

A wild, mature, gravid female mule deer (Odocoileus hemionus) was presented with marked neurological signs, including abnormal behaviour, circling and incoordination. The animal was humanely destroyed and submitted for diagnostic investigation. Grossly, a well-demarcated, 3 × 3 × 3 cm intracranial mass replaced the left olfactory bulb and frontal lobe. Histologically, there was a highly cellular, infiltrative and unencapsulated neoplastic mass of round cells with eccentrically located nuclei. Neoplastic cells were immunohistochemically labelled for lambda immunoglobulin light chain. Clusters of CD20- and CD79a-positive cells were scattered throughout the tumour and CD3- and Iba1-positive cells diffusely infiltrated the neoplasm. Ultrastructurally, the cytoplasm of the neoplastic cells had prominent rough endoplasmic reticulum with a variable degree of dilation. Histopathological, immunohistochemical and electron microscopical results were diagnostic for a solitary extramedullary plasmacytoma. Intracranial neoplasms are rarely diagnosed in wildlife species, but they should be included in the differential diagnosis for potential causes of central nervous system disease. Copyright © 2016 Elsevier Ltd. All rights reserved.

Adenoviral hemorrhagic disease in California mule deer, 1990-2014.

PubMed

Woods, Leslie W; Schumaker, Brant A; Pesavento, Patricia A; Crossley, Beate M; Swift, Pamela K

2018-03-01

We reviewed case records from the California Animal Health and Food Safety (CAHFS) laboratory and the California Department of Fish and Wildlife (CDFW) spanning 25 years (1990-2014) for all deer accessions submitted to CAHFS for pathology and/or histopathology, with and without a diagnosis of adenoviral hemorrhagic disease (AHD), in order to determine the prevalence of AHD in California. We also examined spatial and temporal distribution, age, and mule deer subspecies in deer that died from AHD. Of 483 deer submitted to CAHFS for diagnostic testing in 1990-2014, 17.2% were diagnosed with confirmed AHD, and 26.5% were confirmed plus suspected cases of AHD. Columbian black-tailed deer ( Odocoileus hemionus columbianus), particularly fawns and juveniles, were most frequently affected. Deer adenovirus ( Odocoileus adenovirus 1; OdAdV-1) was detected by immunohistochemistry in archived CDFW formalin-fixed, paraffin-embedded tissues from deer that died in mortality events in 1981, 1983, and 1986-1987. OdAdV-1 is a common cause of hemorrhagic disease mortality events in California deer, and mortality as a result of AHD is documented as early as 1981.

On the water transport of animals with special reference to Denmark.

PubMed

Katić, Ivan; Bajt, Vesna Vucevac

2009-01-01

Transport of animals by water is a very old way of transport because it is relatively cheap and safe, with a minimum loss of animals. Waterways have been used for the transport of living animals and various goods from ancient times, for example in Ancient Egypt and the Roman Empire. Later, Vikings were so successful in their conquests because they always had trained horses aboard. It is believed that the colonization of America was possible because Spaniards were also bringing many horses with them. Danish possessions in the Caribbean owe much of their economic success in the period between 1820 and 1920 to permanent supply of cheap mules and other equides from South America. Mules were used for agricultural purposes and for work in sugar-cane mills. In the 20th century, a significant number of animals was transported to German and British colonies in South Africa. During the First and the Second World War, animals were also transported by water; measures were taken to meet the fundamental physiological requirements, and a veterinarian accompanied animals on long voyages. These precautions resulted in minimum transport losses.

Retrospective investigation of chronic wasting disease of cervids at the Toronto Zoo, 1973–2003

PubMed Central

Dubé, Caroline; Mehren, Kay G.; Barker, Ian K.; Peart, Brian L.; Balachandran, Aru

2006-01-01

The occurrence of chronic wasting disease (CWD) at the Toronto Zoo was investigated retrospectively, based on an examination of management, animal health, and postmortem records, and immunohistochemical studies. Records of animal movements, clinical signs, and postmortem findings were examined for all cervids 1973–2003. All available samples of fixed, wax-embedded lymphoid or central nervous system tissue from cervids that died at the Toronto Zoo from 1973 to 2003, > 12 months of age, were tested, using prion protein immunostaining. Chronic wasting disease prion antigen was detected in 8 of 105 animals tested: 7 mule deer and 1 black-tailed deer. The most likely method of introduction was the importation of CWD-infected animals from a zoo in the United States. Animal-to-animal contact and environmental contamination were the most likely methods of spread of CWD at the zoo. No mule deer left the Toronto Zoo site, and the last animal with CWD died in 1981. Historic findings and ongoing testing of cervids indicate that the Toronto Zoo collection has very low risk of currently being infected with CWD. PMID:17217088

Movement reveals scale dependence in habitat selection of a large ungulate.

PubMed

Northrup, Joseph M; Anderson, Charles R; Hooten, Mevin B; Wittemyer, George

2016-12-01

Ecological processes operate across temporal and spatial scales. Anthropogenic disturbances impact these processes, but examinations of scale dependence in impacts are infrequent. Such examinations can provide important insight to wildlife-human interactions and guide management efforts to reduce impacts. We assessed spatiotemporal scale dependence in habitat selection of mule deer (Odocoileus hemionus) in the Piceance Basin of Colorado, USA, an area of ongoing natural gas development. We employed a newly developed animal movement method to assess habitat selection across scales defined using animal-centric spatiotemporal definitions ranging from the local (defined from five hour movements) to the broad (defined from weekly movements). We extended our analysis to examine variation in scale dependence between night and day and assess functional responses in habitat selection patterns relative to the density of anthropogenic features. Mule deer displayed scale invariance in the direction of their response to energy development features, avoiding well pads and the areas closest to roads at all scales, though with increasing strength of avoidance at coarser scales. Deer displayed scale-dependent responses to most other habitat features, including land cover type and habitat edges. Selection differed between night and day at the finest scales, but homogenized as scale increased. Deer displayed functional responses to development, with deer inhabiting the least developed ranges more strongly avoiding development relative to those with more development in their ranges. Energy development was a primary driver of habitat selection patterns in mule deer, structuring their behaviors across all scales examined. Stronger avoidance at coarser scales suggests that deer behaviorally mediated their interaction with development, but only to a degree. At higher development densities than seen in this area, such mediation may not be possible and thus maintenance of sufficient habitat with lower development densities will be a critical best management practice as development expands globally. © 2016 by the Ecological Society of America.

Simultaneous separation of taxon-specific crystallins from Mule duck and characterization of their enzymatic activities and structures.

PubMed

Wang, Chih-Hsien; Huang, Chia-Chi; Chen, Wenlung

2017-05-15

Methods to obtain pure proteins in large amounts are indispensible in protein research. We report here a large-scale/simultaneous isolation of taxon-specific crystallins (ɛ- and δ-crystallin) from the eye lenses of Mule duck. We also investigate the compositions, enzymatic activities, and structures of these purified taxon-specific proteins. A relatively mild method of ion-exchange chromatography was developed to fractionate ɛ-crystallin and δ-crystallin in large amount, ca. ∼6.60mg/g-lens and ∼41.0mg/g-lens, respectively. Both crystallins were identified by electrophoresis, HPLC, and MALDI-TOF-MS. ɛ-Crystallin, with native composition of M r 142kDa, consisted of two subunits of 35kDa and 36kDa, while δ-Crystallin, with native molecular mass of 200kDa, comprised single subunit of M r ∼50kDa. Both ɛ- and δ-crystallin were tetramers. The former showed lactate dehydrogenase (LDH) activity, while the latter appeared slightly active in an argininosuccinate lyase (ASL) assay. Raman spectroscopic results indicated that the secondary structures of ɛ- and δ-crystallin were predominantly α-helix as evidenced by the vibrational stretching of amide III over 1260cm -1 and amide I at 1255cm -1 , in greatly contrast to the anti-parallel β-sheet of α- and β-crystallin as demonstrated by amide III at 1238cm -1 and amide I at 1672cm -1 . The microenvironments of aromatic amino acids and the status of thiol groups also vary in different crystallins. The compositions, enzyme activities, and structures of the ɛ- and δ-crystalline of Mule duck are different from those of Muscovy duck (Cairina moschata) or Kaiya duck (Anas Platyrhynchos var. domestica), which reflect faithfully species specificity. Copyright © 2017 Elsevier B.V. All rights reserved.

Testicular lesions and antler abnormalities in Colorado, USA mule deer (Odocoileus hemionus): a possible role for epizootic hemorrhagic disease virus.

PubMed

Fox, Karen A; Diamond, Brandon; Sun, Feng; Clavijo, Alfonso; Sneed, Loyd; Kitchen, Donald N; Wolfe, Lisa L

2015-01-01

Antler abnormalities of deer and other cervids often result from testicular lesions and decreased levels of testosterone, inhibiting normal cycles of antler growth. Affected males have antlers with retained velvet, numerous short, misshapen points ("cactus bucks"), and failure to shed these abnormal antlers annually. In Colorado, US, we observed a high occurrence of "cactus bucks" in mule deer (Odocoileus hemionus) populations after management efforts to increase the number of mature male deer in the state. Affected males consistently had antibody to epizootic hemorrhagic disease virus serotype 2 (EHDV-2), and examination of the testes of these animals demonstrated nonspecific end-stage lesions of chronic inflammation, fibrosis, and mineralization. To examine more acute stages of testicular lesions, and to screen for EHDV specifically within the testes, we sampled 16 male mule deer from affected herds, but with essentially normal antlers (n = 14) or retained velvet only (n = 2). Testicular and epididymal lesions identified from these samples included necrotizing vasculitis (n = 2), hemorrhage (n = 6), edema (n = 2), seminiferous tubular necrosis (n = 5), orchitis (n = 5), epididymitis (n = 10), hypospermia (n = 6), and end-stage lesions of seminiferous tubular loss (n = 2), fibrosis (n = 2), and mineralization (n = 2). Each of the 16 cases was blindly scored on the basis of number of histologic lesions, with a median score of two. Five of seven (71%) testes that were PCR positive for EHDV had lesion scores above the median, whereas none of the nine (0%) EHDV PCR-negative testes had lesion scores above the median, suggesting an association between testicular lesions and detection of EHDV RNA in the testes (P = 0.003). Although the role of EHDV infection remains unconfirmed, the association between testicular and epididymal lesions and presence of EHDV RNA in the affected tissues suggests that cactus buck antlers may be a sequela of EHDV infection.

Compensatory mortality in mule deer populations: Final technical report, January 1, 1985--December 31, 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

White, G.C.

1989-03-01

The hypothesis of compensatory mortality is critical to understanding population dynamics of wildlife species. This knowledge is vital regardless of whether populations are managed for recreational hunting or habitats are altered via energy development projects. This research tested for compensatory mortality in the juvenile (fawn) portion of a mule deer population. Two experimental manipulations were used employing radio-collared deer. In this study, /approximately/20% of the population was moved from a treatment area and fawn survival rates compared to those on the control area. In the pasture study, deer were stocked in pastures at 3 densities of 44, 89, and 139more » deer/km/sup 2/. Lowering of density in the field portion of the study did not appear to affect fawn survival. This is attributed to not removing enough animals for existing range conditions that have been imparted by high deer densities during the last 3 decades. Also, the effect of removal was tempered by an increase in yearling males brought about by antler-point restrictions during the harvest. Deer removed from the treatment area were used to stock 3 large pastures at low, medium, and high densities of 44, 89, and 139 deer/km/sup 2/, respectively. Fawn survival was significantly different between densities (P < 0.001), with the low density pasture showing the highest survival and the high density pasture showing the lowest survival. The main cause of death was starvation suggesting that food supplies were limiting. A strong compensatory mortality process is operating in this mule deer population as evidenced by the pasture data. We did not detect this process in the field portion of the study because the removal of /approximately/20% of the population was insufficient to allow an immediate improvement in fawn nutrition. The density-dependent survival response in the controlled pasture study demonstrated that compensatory mortality is operating in this population. 57 refs., 7 figs., 6 tabs.« less

Boron isotopes at the catchment scale, a new potential tool to infer critical zone processes.

NASA Astrophysics Data System (ADS)

Gaillardet, J.; Noireaux, J.; Braun, J. J.; Riotte, J.; Louvat, P.; Bouchez, J.; Lemarchand, D.; Muddu, S.; Mohan Kumar, M.; Candaudap, F.

2017-12-01

Boron is a mid-mass element that has two isotopes, 10B and 11B. These isotopes are largely fractioned by a number of chemical, biological and physical processes. Boron as a great affinity for clays and is useful for life, making it a double tracer of critical zone processes. This study focuses on the Mule Hole Critical Zone Observatory in South India. This is part of the French Research Infrastructure OZCAR and has benefited from the fruitful Indo-French collaboration (Indo-French Cell for Water Sciences) for more that 15 years. Boron and its isotopes were measured in the different compartment of the CZ in Mule Hole, vegetation, atmosphere, throughfall, soil, soil water, river water and compared to the behavior of other elements. The well constrained hydrology in Mule Hole allowed us to calculate the main fluxes affecting boron in the Critical Zone and came to the first order conclusion that the recycling of boron by vegetation is by far the most important flux within the system, reaching 15-20 times the catchment outlet flux. From an isotopic point of view, the total range of variation is measured between -3 ‰ and 77‰, with a bedrock value at 10‰ in classical delta unit, making boron a well suited tracer for constraining CZ processes. The flux of boron most enriched in heavy boron is the throughfall, showing the importance of biological processes in controlling the boron isotopic composition of the stream. Boron in soils in depleted in the heavy isotope but is enriched in boron compared to the bedrock, a surprising situation that we interpret as the legacy of a previous stage of transient weathering. These results indicate a strong decoupling between the behaviors of boron at the surface of the CZ and at depth.

Ancient human mitochondrial DNA and radiocarbon analysis of archived quids from the Mule Spring Rockshelter, Nevada, USA.

PubMed

Hamilton-Brehm, Scott D; Hristova, Lidia T; Edwards, Susan R; Wedding, Jeffrey R; Snow, Meradeth; Kruger, Brittany R; Moser, Duane P

2018-01-01

Chewed and expectorated quids, indigestible stringy fibers from the roasted inner pulp of agave or yucca root, have proven resilient over long periods of time in dry cave environments and correspondingly, although little studied, are common in archaeological archives. In the late 1960s, thousands of quids were recovered from Mule Spring Rockshelter (Nevada, USA) deposits and stored without consideration to DNA preservation in a museum collection, remaining unstudied for over fifty years. To assess the utility of these materials as repositories for genetic information about past inhabitants of the region and their movements, twenty-one quids were selected from arbitrary excavation depths for detailed analysis. Human mitochondrial DNA sequences from the quids were amplified by PCR and screened for diagnostic single nucleotide polymorphisms. Most detected single nucleotide polymorphisms were consistent with recognized Native American haplogroup subclades B2a5, B2i1, C1, C1c, C1c2, and D1; with the majority of the sample set consistent with subclades C1, C1c, and C1c2. In parallel with the DNA analysis, each quid was radiocarbon dated, revealing a time-resolved pattern of occupancy from 347 to 977 calibrated years before present. In particular, this dataset reveals strong evidence for the presence of haplogroup C1/C1c at the Southwestern edge of the US Great Basin from ~670 to 980 cal YBP, which may temporally correspond with the beginnings of the so-called Numic Spread into the region. The research described here demonstrates an approach which combines targeted DNA analysis with radiocarbon age dating; thus enabling the genetic analysis of archaeological materials of uncertain stratigraphic context. Here we present a survey of the maternal genetic profiles from people who used the Mule Spring Rockshelter and the historic timing of their utilization of a key natural resource.

Effect of kisspeptin-10, LH and hCG on serum testosterone concentrations in stallions, donkeys and mules.

PubMed

Akhtar, Rana Waseem; Shah, Syed Aftab Hussain; Qureshi, Irfan Zia

2017-10-15

This study was conducted to determine the response of serum testosterone (T) in male equines (stallions, donkeys and mules) after administering intravenous doses of kisspeptin-10 (KP-10), human chorionic gonadotropin (hCG) and luteinizing hormone (LH) and saline as a control. The animals were divided into four groups of three each: Group I, 3 ml of 0.95% saline; Group II, 50 μg KP-10; Group III, 2500 IU hCG and group IV, 400 μg LH. The administration of KP-10 and hCG to stallions resulted in a significant increase in serum T concentration at 240 min; whereas it was significantly higher at 30, 60, 120, and 240 min with LH treatment as compared to pre-dose concentrations. Both KP-10 and hCG significantly elevated the T concentrations in donkeys at 120 and 240 min, respectively; whereas it was significantly higher at 60, 120, and 240 min with LH treatment as compared to pre-dose concentration. Both KP-10 and LH elevated T in donkeys at 240 min as compared to the control and hCG concentrations. After 120 and 240 min, T concentrations in mules were higher (p < 0.05) with administration of KP-10, hCG and LH as compared to the control. In conclusion, the administration of KP-10, hCG and LH elevate the serum T concentration in normal male equines. It is suggested that KP-10 may be useful in situations where an increase in T is desired. Further work is required to determine the effect of KP-10 on T in male equids with reproductive abnormalities before it can be used in clinical situations. Copyright © 2017 Elsevier Inc. All rights reserved.

Increases in residential and energy development are associated with reductions in recruitment for a large ungulate.

PubMed

Johnson, Heather E; Sushinsky, Jessica R; Holland, Andrew; Bergman, Eric J; Balzer, Trevor; Garner, James; Reed, Sarah E

2017-02-01

Land-use change due to anthropogenic development is pervasive across the globe and commonly associated with negative consequences for biodiversity. While land-use change has been linked to shifts in the behavior and habitat-use patterns of wildlife species, little is known about its influence on animal population dynamics, despite the relevance of such information for conservation. We conducted the first broad-scale investigation correlating temporal patterns of land-use change with the demographic rates of mule deer, an iconic species in the western United States experiencing wide-scale population declines. We employed a unique combination of long-term (1980-2010) data on residential and energy development across western Colorado, in conjunction with congruent data on deer recruitment, to quantify annual changes in land-use and correlate those changes with annual indices of demographic performance. We also examined annual variation in weather conditions, which are well recognized to influence ungulate productivity, and provided a basis for comparing the relative strength of different covariates in their association with deer recruitment. Using linear mixed models, we found that increasing residential and energy development within deer habitat were correlated with declining recruitment rates, particularly within seasonal winter ranges. Residential housing had two times the magnitude of effect of any other factor we investigated, and energy development had an effect size similar to key weather variables known to be important to ungulate dynamics. This analysis is the first to correlate a demographic response in mule deer with residential and energy development at large spatial extents relevant to population performance, suggesting that further increases in these development types on deer ranges are not compatible with the goal of maintaining highly productive deer populations. Our results underscore the significance of expanding residential development on mule deer populations, a factor that has received little research attention in recent years, despite its rapidly increasing footprint across the landscape. © 2016 The Authors. Global Change Biology Published by John Wiley & Sons Ltd.

Hepatic minerals of white-tailed and mule deer in the southern Black Hills, South Dakota

USGS Publications Warehouse

Zimmerman, T.J.; Jenks, J.A.; Leslie, David M.; Neiger, R.D.

2008-01-01

Because there is a paucity of information on the mineral requirements of free-ranging deer, data are needed from clinically healthy deer to provide a basis for the diagnosis of mineral deficiencies. To our knowledge, no reports are available on baseline hepatic mineral concentrations from sympatric white-tailed deer (Odocoileus virginianus) and mule deer (Odocoileus hemionus) using different habitats in the Northern Great Plains. We assessed variation in hepatic minerals of female white-tailed deer (n=42) and mule deer (n=41). Deer were collected in February and August 2002 and 2003 from study areas in Custer and Pennington Counties, South Dakota, in and adjacent to a wildfire burn. Hepatic samples were tested for levels (parts per million; ppm) of aluminum (Al), antimony (Sb), arsenic (As), barium (Ba), boron (B), cadmium (Cd), calcium (Ca), chromium (Cr), cobalt (Co), copper (Cu), iron (Fe), lead (Pb), magnesium (Mg), manganese (Mn), mercury (Hg), molybdenum (Mo), nickel (Ni), phosphorus (P), potassium (K), selenium (Se), sodium (Na), sulfur (S), thalium (T1), and zinc (Zn). We predicted that variability in element concentrations would occur between burned and unburned habitat due to changes in plant communities and thereby forage availability. We determined that Zn, Cu, and Ba values differed (P???0.05) between habitats. Because of the nutritional demands of gestation and lactation, we hypothesized that elemental concentrations would vary depending on reproductive status; Cd, Cu, Ca, P, Mn, Mo, Na, and Zn values differed (P???0.05) by reproductive status. We also hypothesized that, due to variation in feeding strategies and morphology between deer species, hepatic elemental concentrations would reflect dietary differences; Ca, Cu, K, Co, Mo, Se, and Zn differed (P???0.05) between species. Further research is needed to determine causes of variation in hepatic mineral levels due to habitat, reproductive status, and species. ?? Wildlife Disease Association 2008.

Combustion of Coal-Mule Briquettes / Spalanie Brykietów Z Mułu Węglowego

NASA Astrophysics Data System (ADS)

Kijo-Kleczkowska, Agnieszka

2013-09-01

Combustion technologies coal-mule fuels create a number of new possibilities for organising combustion processes so that they fulfil contemporary requirements (e.g., in terms of the environment protection- related issues). The paper describes the problems of coal-mule fuel combustion that have acquired a wider significance as the quality requirements of coal combustion in power plants have been growing. Coal mines that want to fulfill expectations of power industry workers have been forced to develop and modernize plants of coal wet cleaning. It all results in the growing amount of waste arising in the process of coal wet cleaning which contains smaller and smaller coal undersizes. In this situation the concept of direct combustion of the above mentioned waste and their co-combustion with other fuels, coal and biomass, seems to be attractive. Biomass is one from the most promising sources of renewable energy. The main aim of the paper is to identify the mechanism and kinetics of combustion of coal-mule fuels and their co- -combustion with coal and biomass in the briquettes form based on extensive experimental research in air. Niekorzystny bilans paliwowy naszego kraju powoduje nadmierne obciążenie środowiska, wywołane emisją CO2, NOx, SO2 i pyłów, a także powiększeniem powierzchni koniecznych na składowanie wciąż narastających stałych odpadów paleniskowych. Górnictwo, od którego energetyka oczekuje coraz lepszego paliwa, musi stosować głębsze wzbogacanie węgla. Powoduje to ciągłą produkcję odpadów w postaci mułów poflotacyjnych. Najlepszą metodą utylizacji tych mułów jest ich spalanie w postaci zawiesin, a także ich współspalanie z innymi paliwami, węglem czy biomasą. Biomasa jest bowiem jednym z najbardziej obiecujących źródeł OZE, a jej współspalanie z paliwami węglowymi znajduje w ostatnich latach coraz szersze zastosowanie zarówno w kraju, jak i na świecie. W tej sytuacji istotne jest prowadzenie badań naukowych, mających na celu identyfikację przebiegu procesu spalania paliw, utworzonych nie tylko z mułów poflotacyjnych, ale również z mieszaniny mułów węglowych oraz pyłów węgla i biomasy. Niniejsza praca podejmuje mechanizm i kinetykę spalania oraz współspalania wspomnianych paliw w postaci brykietów, prowadzonego w strumieniu powietrza

Revisions of rump fat and body scoring indices for deer, elk, and moose

USGS Publications Warehouse

Cook, Rachel C.; Cook, John G.; Stephenson, Thomas R.; Myers, Woodrow L.; Mccorquodale, Scott M.; Vales, David J.; Irwin, Larry L.; Hall, P. Briggs; Spencer, Rocky D.; Murphie, Shannon L.; Schoenecker, Kathryn A.; Miller, Patrick J.

2010-01-01

Because they do not require sacrificing animals, body condition scores (BCS), thickness of rump fat (MAXFAT), and other similar predictors of body fat have advanced estimating nutritional condition of ungulates and their use has proliferated in North America in the last decade. However, initial testing of these predictors was too limited to assess their reliability among diverse habitats, ecotypes, subspecies, and populations across the continent. With data collected from mule deer (Odocoileus hemionus), elk (Cervus elaphus), and moose (Alces alces) during initial model development and data collected subsequently from free-ranging mule deer and elk herds across much of the western United States, we evaluated reliability across a broader range of conditions than were initially available. First, to more rigorously test reliability of the MAXFAT index, we evaluated its robustness across the 3 species, using an allometric scaling function to adjust for differences in animal size. We then evaluated MAXFAT, rump body condition score (rBCS), rLIVINDEX (an arithmetic combination of MAXFAT and rBCS), and our new allometrically scaled rump-fat thickness index using data from 815 free-ranging female Roosevelt and Rocky Mountain elk (C. e. roosevelti and C. e. nelsoni) from 19 populations encompassing 4 geographic regions and 250 free-ranging female mule deer from 7 populations and 2 regions. We tested for effects of subspecies, geographic region, and captive versus free-ranging existence. Rump-fat thickness, when scaled allometrically with body mass, was related to ingesta-free body fat over a 38–522-kg range of body mass (r2 = 0.87; P < 0.001), indicating the technique is remarkably robust among at least the 3 cervid species of our analysis. However, we found an underscoring bias with the rBCS for elk that had >12% body fat. This bias translated into a difference between subspecies, because Rocky Mountain elk tended to be fatter than Roosevelt elk in our sample. Effects of observer error with the rBCS also existed for mule deer with moderate to high levels of body fat, and deer body size significantly affected accuracy of the MAXFAT predictor. Our analyses confirm robustness of the rump-fat index for these 3 species but highlight the potential for bias due to differences in body size and to observer error with BCS scoring. We present alternative LIVINDEX equations where potential bias from rBCS and bias due to body size are eliminated or reduced. These modifications improve the accuracy of estimating body fat for projects intended to monitor nutritional status of herds or to evaluate nutrition's influence on population demographics.

3 CFR 8868 - Proclamation 8868 of September 21, 2012. Establishment of the Chimney Rock National Monument

Code of Federal Regulations, 2013 CFR

2013-01-01

... of the San Juan Mountains. Migratory mule deer and elk herds pass through the area each fall and... turkeys, river otters, bald eagles, golden eagles, mountain lions, bats, woodpeckers, and many species of... usually found farther south grow there, including a species of cholla cactus that does not occur naturally...

Characterization of the first case of naturally occurring chronic wasting disease in a captive red deer (Cervus elaphus) in North America

USDA-ARS?s Scientific Manuscript database

Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) affecting cervids that is caused by the accumulation of an abnormal prion protein. CWD has been diagnosed in captive and free-ranging elk (Cervus canadensis), mule deer (Odocoileus hemionus), white-tailed deer (Odocoile...

Chronic wasting disease in bank voles: characterisation of the shortest incubation time model for prion diseases

USDA-ARS?s Scientific Manuscript database

In order to assess the susceptibility of bank voles to chronic wasting disease (CWD), we inoculated voles carrying isoleucine or methionine at codon 109 (Bv109I and Bv109M, respectively) with CWD isolates from elk, mule deer and white-tailed deer. Efficient transmission rate (100%) was observed with...

Protocols for care and handling of deer and elk at the Starkey Experimental Forest and Range.

Treesearch

M.J. Wisdom; J.G. Cook; M.M. Rowland; J.H. Noyes

1993-01-01

Several hundred Rocky Mountain elk (Cervus elaphus nelsomi V. Bailey and Rocky Mountain mule deer (Odocoileus hemionus hemionus Rafinesque) inhabit a fenced, 25,000-acre enclosure at the Starkey Experimental Forest and Range in the Blue Mountains of northeast Oregon. Research there requires handling most of these animals each...

"Forty Acres and a Mule," With Interest: The Constitutionality of Black Capitalism, Benign School Quotas, and Other Statutory Racial Classifications

ERIC Educational Resources Information Center

Elden, Gary

1969-01-01

This article traces the growth and assesses contemporary patterns and consequences of, discrimination against the American Negro. The author contends that public policies designed to support black capitalism" and implement school racial quotas, are not only legal but necessary means toward achieving true equality of opportunity. (JH)

"On the Hurricane Deck of a Mule": Teaching Adults To Read Using Language-Experience and Oral History Techniques.

ERIC Educational Resources Information Center

Bear, Donald R.

Designed to instruct adult literacy teachers in using Language-Experience and Oral History techniques and distributed statewide to teachers in Nevada, this manual presents reading materials, diagnostic packages, and guidelines for adult literacy program organization. The first of three chapters begins with an introduction to the manual, and…

Experimental oral transmission of chronic wasting disease to red deer (Cervus elaphus elaphus): Early detection and late stage distribution of protease-resistant prion protein

USDA-ARS?s Scientific Manuscript database

Chronic wasting disease CWD is the transmissible spongiform encephalopathy or prion disease of wild and farmed cervid ruminants, including Rocky Mountain elk (Cervus elaphus nelsoni), white tailed deer (Odocoileus virginianus), mule deer (Odocoileus hemionus), or moose (Alces alces). Reliable data ...

Proceedings of the 15th wildland shrub symposium; June 17-19, 2008; Bozeman, MT

Treesearch

Carl L. Wambolt; Stanley G. Kitchen; Michael R. Fisina; Bok Sowell; Richard B. Keigley; Patsy Palacios; Jill Robinson

2011-01-01

The 35 papers in this proceedings are divided into four sections; the first includes an introduction to the symposium theme of Shrublands as wildlands and wildlife habitat, along with keynote addresses discussing geographic affiliations of eastern Montana's "great Plains Flora" and methodology for surveying mule deer winter range habitat use and...

Challenges in identifying and determining the impacts of infection with pestiviruses on the herd health of free ranging cervid populations

USDA-ARS?s Scientific Manuscript database

Although most commonly associated with the infection of domestic livestock, the replication of pestiviruses, in particular bovine viral diarrhea virus (BVDV), occurs in a wide range of free ranging cervids including white-tailed deer, mule deer, fallow deer, elk, red deer, roe deer, eland and moused...

Colic Caused by Panicum maximum Toxicosis in Equidae in Northern Brazil

USDA-ARS?s Scientific Manuscript database

In the Amazon region of northern Brazil, Panicum maximum cultivars Mombaça, Tanzânia, and Massai cause severe colic and death in horses and mules. The disease occurs in the rainy season, when sprouting pastures are grazed by equidae. In the 8 separate disease outbreaks studied, a total of 52 out of ...

9 CFR 312.3 - Official marks and devices to identify inspected and passed equine products.

Code of Federal Regulations, 2010 CFR

2010-01-01

... inspected and passed equine products. 312.3 Section 312.3 Animals and Animal Products FOOD SAFETY AND... § 312.3 Official marks and devices to identify inspected and passed equine products. (a) The official... § 317.2 of this subchapter to identify inspected and passed mule and other (nonhorse) equine carcasses...

Towards Commanding Unmanned Ground Vehicle Movement in Unfamiliar Environments Using Unconstrained English: Initial Research Results

DTIC Science & Technology

2007-06-01

constrained list of command words could be valuable in many systems, as would the ability of driverless vehicles to navigate through a route...Sensemaking in UGVs • Future Combat Systems UGV roles – Driverless trucks – Robotic mules (soldier, squad aid) – Intelligent munitions – And more! • Some

Keep trophy records honest: Identifying whitetail/mule deer hybrids

Treesearch

Jim Heffelfinger; Renee Prive; David Paetkau; Carlos Alcala-Galvan; Roy Lopez; Irv Kornfield; Eldon Buckner

2012-01-01

Humans have always been fascinated by hybrids. Consider such classic monsters as Wolfman, Dracula, and Mothmanor heroes such as Spiderman, Batman, and Catwoman. This trend pre-dates Hollywood by millennia; the "Minotaur" in Greek mythology was half man and half bull. Our fascination with creatures that are half one thing and half another extends to wildlife....

Wetlands Research Program. Corps of Engineers Wetlands Delineation Manual. Appendix C. Section 1. Region O - California.

DTIC Science & Technology

1987-01-01

baccharis FAG B. sergiZoides A. Gray Squaw waterveed baccharis FAC B. viminea DC. Mule fat FACW 3acopa eiserii (Kell.) Penn. Eisen bacopa OBL B. nobs ia...nr ao Bacopa ORL Barbarea orthoceras Ledeb. Erectpod vintercress B. vutgaris R. Br. Bitter vintercress FACW Bassia hyasopifoZia (Pallas) Kuntze

A multi-scale evaluation of pack stack effects on subalpine meadow plant communities in the Sierra Nevada

USDA-ARS?s Scientific Manuscript database

We evaluated the influence of pack stock (i.e., horse and mule) use on meadow plant communities in Sequoia and Yosemite National Parks in the Sierra Nevada mountains of California. Meadows were sampled to account for inherent variability across multiple scales by: 1) controlling for among-meadow var...

9 CFR 355.43 - Scope and applicability of rules of practice.

Code of Federal Regulations, 2010 CFR

2010-01-01

... Animal Food, Mule Meat By-Product § 355.43 Scope and applicability of rules of practice. The rules of... 9 Animals and Animal Products 2 2010-01-01 2010-01-01 false Scope and applicability of rules of practice. 355.43 Section 355.43 Animals and Animal Products FOOD SAFETY AND INSPECTION SERVICE, DEPARTMENT...

A Case Study in User Support for Managing OpenSim Based Multi User Learning Environments

ERIC Educational Resources Information Center

Perera, Indika; Miller, Alan; Allison, Colin

2017-01-01

Immersive 3D Multi User Learning Environments (MULE) have shown sufficient success to warrant their consideration as a mainstream educational paradigm. These are based on 3D Multi User Virtual Environment platforms (MUVE), and although they have been used for various innovative educational projects their complex permission systems and large…

Implications of managing the timing and intensity of herbivory for conservation of Arizona leatherflower

Treesearch

Joyce Maschinski

2001-01-01

For rare plants, the question of whether and to what extent wild and domestic herbivores influence growth, reproduction, and survival can be critical to preservation. The sensitive species, Clematis hirsutissima var. arizonica, grows on Forest Service lands where cattle, elk, mule deer, and numerous small mammals forage. In a 3-year clipping experiment, I examined the...

User's Guide to "MULE"; McGill University Language for Education. A Computer-Assisted Instruction Author Language.

ERIC Educational Resources Information Center

Roid, Gale H.

A computer-assisted instruction (CAI) author language and operating system is available for use by McGill instructors on the university's IBM 360/65 RAX Time-Sharing System. Instructors can use this system to prepare lessons which allow the computer and a student to "converse" in natural language. The instructor prepares a lesson by…

Clues from Dinosaurs, Mules, and the Bull Snake: Our Field in the 21st Century. The Second Delphine Hanna Interdisciplinary Lecture 1993.

ERIC Educational Resources Information Center

Corbin, Charles B.

1993-01-01

Delphine Hanna was a pioneer in interdisciplinary scholarship and establishment of professional programs in physical education. The paper suggests physical education must follow her example to survive in the future, noting how the profession got where it is, where it is going, and how it can get there. (SM)

26 CFR 1.182-4 - Definition of “land suitable for use in farming”, etc.

Code of Federal Regulations, 2010 CFR

2010-04-01

... (continued) § 1.182-4 Definition of “land suitable for use in farming”, etc. For purposes of section 182, the term land suitable for use in farming means land which, as a result of the land clearing activities... term livestock includes cattle, hogs, horses, mules, donkeys, sheep, goats, captive fur-bearing animals...

77 FR 27111 - Office of Commercial Space Transportation (AST); Notice of Availability of the Final...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-08

... Policy Act of 1969, as amended (NEPA; 42 U.S.C. 4321 et seq.), Council on Environmental Quality NEPA... Base Library, 95 SPTG/SVMG, 5 West Yeager Blvd., Building 2665, Edwards AFB, CA 93524-1295. Kern County Library, Boron Branch, 26967 20 Mule Team Road, Boron, CA 93516. Kern County Library, California City...

Effects of season and scale on response of elk and mule deer to habitat manipulation

Treesearch

Ryan A. Long; Janet L. Rachlow; John G. Kie

2008-01-01

Manipulation of forest habitat via mechanical thinning or prescribed fire has become increasingly common across western North America. Nevertheless, empirical research on effects of those activities on wildlife is limited, although prescribed fire in particular often is assumed to benefit large herbivores. We evaluated effects of season and spatial scale on response of...

Elk and mule deer responses to variation in hunting pressure.

Treesearch

Bruce K. Johnson; Alan A. Ager; James H. Noyes; Norm Cimon

2004-01-01

Hunting can exert a variety of effects on both targeted and nontargeted ungulates, and animals either run or hide in response to hunting pressure. If animals successfully elude hunters by running, the energetic cost may deplete fat reserves needed for survival during winter in temperate regions. If animals successfully elude hunters by hiding, there may be an energetic...

9 CFR 75.4 - Interstate movement of equine infectious anemia reactors and approval of laboratories, diagnostic...

Code of Federal Regulations, 2010 CFR

2010-01-01

...: (1) The description, including age, breed, color, sex, and distinctive markings when present (such as... self-locking device on one end and a slot on the other end, which forms a loop when the ends are..., including name, age, sex, breed, color, and markings. Reactor. Any horse, ass, mule, pony or zebra which is...

Hikers and recreational stock users: Predicting and managing recreation conflicts in three wildernesses

Treesearch

Alan E. Watson; Michael J. Niccolucci; Daniel R. Williams

1993-01-01

A long-term problem that continues to grow in many wildland areas is the displeasure hikers express about meeting recreational livestock (primarily horses and mules) and seeing impacts from stock use. Three studies were conducted to provide a broad look at this interaction in wilderness and some of the contributors to the conflict between hikers and horse users....

Effects of off-road recreation on mule deer and elk.

Treesearch

Michael J. Wisdom; Alan A. Ager; Haiganoush K. Preisler; Norman J. Cimon; Bruce K. Johnson

2004-01-01

Off-road recreation is increasing rapidly in the United States, especially on public land (Havlick 2002, U.S. Department of Agriculture Forest Service 2004). An expansive network of roads provides easy access to much public land, which facilitates off-road uses in the form of all-terrain vehicles (ATVs), horses, mountain bikes and foot traffic. No research, however,...

Anticipating forest and range land development in central Oregon (USA) for landscape analysis, with an example application involving mule deer

Treesearch

Jeffrey D. Kline; Alissa Moses; Theresa Burcsu

2010-01-01

Forest policymakers, public lands managers, and scientists in the Pacific Northwest (USA) seek ways to evaluate the landscape-level effects of policies and management through the multidisciplinary development and application of spatially explicit methods and models. The Interagency Mapping and Analysis Project (IMAP) is an ongoing effort to generate landscape-wide...

WLCI researchers employ new approaches to help managers conserve deer migrations

USGS Publications Warehouse

Allen, Leslie A.; Kauffman, Matthew J.

2012-01-01

Elk, mule deer, pronghorn antelope, moose, and bighorn sheep are iconic animals of the American West. These hooved animals, known as ungulates, commonly travel 30–60 miles between seasonal ranges. These migrations between winter and summer ranges are vital for survival and reproduction. As habitat fragmentation continues, the conservation of ungulate migration routes has received considerable attention in the West and across the globe. For example, it is estimated that many ungulate migration routes in the Greater Yellowstone Ecosystem have already been lost. The traditional migration routes of Wyoming ungulates are threatened by unprecedented levels of energy development and by increasing levels of rural ranchette development (including fences, structures, and roads). In the past, migration corridors have been mapped based primarily on the expert opinions of state game managers, but long-term conservation of Wyoming's ungulate migration routes requires a better understanding of migration ecology and more sophisticated management tools. Wyoming Landscape Conservation Initiative (WLCI) researchers investigated the migration of a large mule deer herd across the Dad and Wild Horse winter ranges in southwest Wyoming, where 2,000 gas wells and 1,609 kilometers of pipelines and roads have been proposed for development.

Random X inactivation in the mule and horse placenta.

PubMed

Wang, Xu; Miller, Donald C; Clark, Andrew G; Antczak, Douglas F

2012-10-01

In eutherian mammals, dosage compensation of X-linked genes is achieved by X chromosome inactivation. X inactivation is random in embryonic and adult tissues, but imprinted X inactivation (paternal X silencing) has been identified in the extra-embryonic membranes of the mouse, rat, and cow. Few other species have been studied for this trait, and the data from studies of the human placenta have been discordant or inconclusive. Here, we quantify X inactivation using RNA sequencing of placental tissue from reciprocal hybrids of horse and donkey (mule and hinny). In placental tissue from the equid hybrids and the horse parent, the allelic expression pattern was consistent with random X inactivation, and imprinted X inactivation can clearly be excluded. We characterized horse and donkey XIST gene and demonstrated that XIST allelic expression in female hybrid placental and fetal tissues is negatively correlated with the other X-linked genes chromosome-wide, which is consistent with the XIST-mediated mechanism of X inactivation discovered previously in mice. As the most structurally and morphologically diverse organ in mammals, the placenta also appears to show diverse mechanisms for dosage compensation that may result in differences in conceptus development across species.

Parental genomes mix in mule and human cell nuclei.

PubMed

Hepperger, Claudia; Mayer, Andreas; Merz, Julia; Vanderwall, Dirk K; Dietzel, Steffen

2009-06-01

Whether chromosome sets inherited from father and mother occupy separate spaces in the cell nucleus is a question first asked over 110 years ago. Recently, the nuclear organization of the genome has come increasingly into focus as an important level of epigenetic regulation. In this context, it is indispensable to know whether or not parental genomes are spatially separated. Genome separation had been demonstrated for plant hybrids and for the early mammalian embryo. Conclusive studies for somatic mammalian cell nuclei are lacking because homologous chromosomes from the two parents cannot be distinguished within a species. We circumvented this problem by investigating the three-dimensional distribution of chromosomes in mule lymphocytes and fibroblasts. Genomic DNA of horse and donkey was used as probes in fluorescence in situ hybridization under conditions where only tandem repetitive sequences were detected. We thus could determine the distribution of maternal and paternal chromosome sets in structurally preserved interphase nuclei for the first time. In addition, we investigated the distribution of several pairs of chromosomes in human bilobed granulocytes. Qualitative and quantitative image evaluation did not reveal any evidence for the separation of parental genomes. On the contrary, we observed mixing of maternal and paternal chromosome sets.

Prevalence of lesions in incisors of mule deer from Colorado Springs, Colorado

DOE Office of Scientific and Technical Information (OSTI.GOV)

Borrero, L.M.; Scanlon, P.F.

1995-12-31

Lesions in teeth may be influenced by exposure to fluorides, malnutrition and trauma. Incisors of 228 mule deer (Odocoileus hemionus) taken from the USAF Academy, Colorado Springs, CO during the 1993 hunting season were examined for lesions. A classification scheme (scale = 0--5) for lesions was derived from the method of Shupe et al. 1963. Lesions were present in at least one incisor of 84.6% of deer. Of the deer with lesions, 86% had at least one tooth with very slight effect (one to few white spots), 9.8% had a slight effect (generalized mottling), 2.6% had a moderate effect (generalizedmore » mottling and wear), 10.04% had a marked effect (mottling and hypoplasia of the enamel) , and 0.5 % ad severe effects (hypoplasia of the enamel and abnormal wear). Lesions that affect the enamel are produced during the period of formation of the tooth. The severity of lesions depends on the cause and the length of exposure to the causative agent. Generally mottling and hypoplasia of the enamel are associated with fluorosis. The relationship of lesions to bone and tooth fluoride concentrations was examined.« less

Sensor4PRI: A Sensor Platform for the Protection of Railway Infrastructures

PubMed Central

Cañete, Eduardo; Chen, Jaime; Díaz, Manuel; Llopis, Luis; Rubio, Bartolomé

2015-01-01

Wireless Sensor Networks constitute pervasive and distributed computing systems and are potentially one of the most important technologies of this century. They have been specifically identified as a good candidate to become an integral part of the protection of critical infrastructures. In this paper we focus on railway infrastructure protection and we present the details of a sensor platform designed to be integrated into a slab track system in order to carry out both installation and maintenance monitoring activities. In the installation phase, the platform helps operators to install the slab tracks in the right position. In the maintenance phase, the platform collects information about the structural health and behavior of the infrastructure when a train travels along it and relays the readings to a base station. The base station uses trains as data mules to upload the information to the internet. The use of a train as a data mule is especially suitable for collecting information from remote or inaccessible places which do not have a direct connection to the internet and require less network infrastructure. The overall aim of the system is to deploy a permanent economically viable monitoring system to improve the safety of railway infrastructures. PMID:25734648

Use of yohimbine and 4-aminopyridine to antagonize xylazine-induced immobilization in North American Cervidae.

PubMed

Renecker, L A; Olsen, C D

1985-12-01

Four captive moose (Alces alces), 4 mule deer (Odocoileus hemionus), and 5 white-tailed deer (Odocoileus virginianus) were immobilized with xylazine (0.63 to 1.29 mg/kg of body weight, IM). Mean induction times for the moose were 17 minutes and for the deer, 14 and 10 minutes, respectively. According to published data and past experience, the dosage of xylazine used would be expected to provide 115, 120, and 100 minutes of immobilization in captive moose, mule deer, and white-tailed deer, respectively. In the present study, maximal sedation of the moose and deer was reversed with successive injections (given IV) of yohimbine (0.15 mg/kg) and 4-aminopyridine (0.26 to 0.29 mg/kg). These produced sternal recumbency-to-arousal intervals of 1 to 15 minutes and recumbency-to-standing or walking intervals of 1 to 24 minutes. Relapses to recumbency were not observed. The injections of the reversal drugs produced marked increases in respiratory rate and heart in the moose and deer, without occurrence of muscle tremors or convulsions. The administrations of yohimbine and 4-aminopyridine markedly enhanced the speed of recovery from xylazine-induced immobilization in moose and deer.

Isolation and characterization of a distinct duck-origin goose parvovirus causing an outbreak of duckling short beak and dwarfism syndrome in China.

PubMed

Chen, Shilong; Wang, Shao; Cheng, Xiaoxia; Xiao, Shifeng; Zhu, Xiaoli; Lin, Fengqiang; Wu, Nanyang; Wang, Jinxiang; Huang, Meiqing; Zheng, Min; Chen, Shaoying; Yu, Fusong

2016-09-01

Many mule duck and Cherry Valley duck flocks in different duck-producing regions of China have shown signs of an apparently new disease designated "short beak and dwarfism syndrome" (SBDS) since 2015. The disease is characterized by dyspraxia, weight loss, a protruding tongue, and high morbidity and low mortality rates. In order to characterize the etiological agent, a virus designated SBDSV M15 was isolated from allantoic fluid of dead embryos following serial passage in duck embryos. This virus causes a cytopathic effect in duck embryo fibroblast (DEF) cells. Using monoclonal antibody diagnostic assays, the SBDSV M15 isolate was positive for the antigen of goose parvovirus but not Muscovy duck parvovirus. A 348-bp (2604-2951) VP1gene fragment was amplified, and its sequence indicated that the virus was most closely related to a Hungarian GPV strain that was also isolated from mule ducks with SBDS disease. A similar disease was reproduced by inoculating birds with SBDSV M15. Together, these data indicate that SBDSV M15 is a GPV-related parvovirus causing SBDS disease and that it is divergent from classical GPV isolates.

The Fort Valley Experimental Forest, ponderosa pine, and wildlife habitat research (P-53)

Treesearch

David R. Patton

2008-01-01

Wildlife research at the Fort Valley Experimental Forest began with studies to determine how to control damage by wildlife and livestock to ponderosa pine (Pinus ponderosa) reproduction and tree growth. Studies on birds, small mammals, and mule deer (Odocoileus hemionus) browsing were initiated in the early 1930s and 1940s but these were short term efforts to develop...

Women Warriors: Why the Robotics Revolution Changes the Combat Equation

DTIC Science & Technology

2015-01-01

combat fight due in large part to advances in robotics and autonomous systems. From exoskeletons to robotic mules, technology is reducing the...kick-started innovation in this area in 2001 by funding labs, industry, and universities under the Exoskeletons for Human Performance Augmentation...and fledgling programs of record. The Human Load Carrier (HULC), for example, is a hydraulic- powered exoskeleton made of titanium that allows

The Animal Pathogen-Like Type III Secretion System is Required for the Intracellular Survival of Burkholderia mallei within J774.2 Macrophages

DTIC Science & Technology

2006-03-30

for B. mallei are horses, donkeys, and mules (solipeds), but other animals, including mice, hamsters, guinea pigs, monkeys , lions, and dogs, are...Spa/Prg and Shigella Ipa/Mxi/Spa TTS networks, are important for in vitro and in vivo survival of these pathogenic Burkholderia species (9–12, 14, 15

Effects of replacing corn with sorghum on the performance of overfed mule ducks.

PubMed

Arroyo, J; Dubois, J P; Lavigne, F; Brachet, M; Fortun-Lamothe, L

2016-06-01

The aim of this trial was to study the effects of replacing yellow corn (C) with condensed tannin-free sorghum (S) during the finishing period (F period; age 53 to 79 d) and/or overfeeding period (O period; age 80 to 91 d) on the performance of overfed mule ducks. 192 ducks were divided into 4 groups (48 in each) differing in the cereal (yellow corn or sorghum) included in the diet given during the F and/or the O periods, using a 2 × 2 factorial arrangement of treatments : SS, SC, CS, CC. At the end of the O period, the birds were slaughtered after 10 h of fasting to measure foie gras and magret qualities. Mortality (1%; P > 0.05) and weight gain (2,030 g; P > 0.05) during the O period were similar in the 4 groups. At the end of the O period, birds overfed with sorghum had foie gras that was heavier (723 vs. 694 g in CS+SS vs. CC+SC, respectively; P < 0.05) and less yellow (24.40 vs. 38.59 for b* in CS+SS vs. CC+SC, respectively; P < 0.001) than birds overfed with corn. Fat loss during foie gras cooking was similar in the 4 groups (18%; P > 0.05), but the foie gras was less yellow in birds overfed with sorghum (14.84 vs. 26.01 for b* in CS+SS vs. CC+SC, respectively; P < 0.001). Weight of magret was similar in the 4 groups (491 g, P > 0.05) but the color of the breast muscle and skin of magret was less yellow in birds overfed with sorghum compared with corn (12.26 vs. 12.92 and 13.84 vs. 18.30 in CS+SS vs. CC+SC, respectively; P < 0.001). In conclusion, the replacement of yellow corn with sorghum during finishing and/or overfeeding is possible and useful in a mule duck foie gras production system because it increases foie gras weight without decreasing the weight of magret However, it changes the quality of the products, mainly their color. © 2016 Poultry Science Association Inc.

Impact of selection for residual feed intake on production traits and behavior of mule ducks.

PubMed

Drouilhet, L; Monteville, R; Molette, C; Lague, M; Cornuez, A; Canario, L; Ricard, E; Gilbert, H

2016-09-01

A divergent selection experiment of Muscovy sires based on the residual feed intake (RFI) of their male mule progeny was initiated in 2009. Using electronic feeders, the aim of this study was to establish whether 3 generations of selection for RFI had an impact on feeding behavior traits and general behavior, and to examine its effect on liver and meat quality. Eighty mule ducks, issued from 8 Muscovy drakes per line with extreme RFI, were tested in a pen equipped with 4 electronic feeders. Feeding behaviors were recorded from 3 to 7 wk after hatching under ad libitum feeding conditions. Then animals were prepared for overfeeding with a 3-week period of restricted feeding, and overfed during 12 d before slaughter. The RFI was significantly lower in the low RFI line than in the high RFI line (-5.4 g/d, P = 0.0005) and daily feed intake was reduced both over the entire test period (-5 g/d, P = 0.049) and on a weekly basis (P = 0.006). Weekly and total feed conversion ratios were also significantly lower (-0.08, P = 0.03 and -0.06, P = 0.01, respectively). Low RFI ducks had more frequent meals, spent as much time eating as high RFI ducks, and their feeding rate was lower when analyzed at the wk level only. Additionally no significant correlation between feed efficiency and feeding behavior traits was evidenced, indicating only limited relationships between RFI and feeding patterns. Some differences in behavioral responses to stressors (open field test combined with a test measuring the response to human presence) suggested that a lower RFI is associated with less fearfulness. Selection for RFI had no effect on liver weight and quality and a slightly deleterious impact on meat quality (decreased drip loss and L*). Finally, low RFI animals had higher body weights after restricted feeding from wk 10 to wk 12 and after overfeeding than high RFI ducks. This suggests that selection for reduced RFI until 7 wk of age increases the feed efficiency up to slaughter. © The Author 2016. Published by Oxford University Press on behalf of Poultry Science Association.

Impact of selection for residual feed intake on production traits and behavior of mule ducks

PubMed Central

Drouilhet, L.; Monteville, R.; Molette, C.; Lague, M.; Cornuez, A.; Canario, L.; Ricard, E.; Gilbert, H.

2016-01-01

A divergent selection experiment of Muscovy sires based on the residual feed intake (RFI) of their male mule progeny was initiated in 2009. Using electronic feeders, the aim of this study was to establish whether 3 generations of selection for RFI had an impact on feeding behavior traits and general behavior, and to examine its effect on liver and meat quality. Eighty mule ducks, issued from 8 Muscovy drakes per line with extreme RFI, were tested in a pen equipped with 4 electronic feeders. Feeding behaviors were recorded from 3 to 7 wk after hatching under ad libitum feeding conditions. Then animals were prepared for overfeeding with a 3-week period of restricted feeding, and overfed during 12 d before slaughter. The RFI was significantly lower in the low RFI line than in the high RFI line (−5.4 g/d, P = 0.0005) and daily feed intake was reduced both over the entire test period (−5 g/d, P = 0.049) and on a weekly basis (P = 0.006). Weekly and total feed conversion ratios were also significantly lower (−0.08, P = 0.03 and −0.06, P = 0.01, respectively). Low RFI ducks had more frequent meals, spent as much time eating as high RFI ducks, and their feeding rate was lower when analyzed at the wk level only. Additionally no significant correlation between feed efficiency and feeding behavior traits was evidenced, indicating only limited relationships between RFI and feeding patterns. Some differences in behavioral responses to stressors (open field test combined with a test measuring the response to human presence) suggested that a lower RFI is associated with less fearfulness. Selection for RFI had no effect on liver weight and quality and a slightly deleterious impact on meat quality (decreased drip loss and L*). Finally, low RFI animals had higher body weights after restricted feeding from wk 10 to wk 12 and after overfeeding than high RFI ducks. This suggests that selection for reduced RFI until 7 wk of age increases the feed efficiency up to slaughter. PMID:27333975

The Port Royal Experiment: Forty Acres and a Mule? A Unit of Study for Grades 8-12.

ERIC Educational Resources Information Center

Vigilante, David

This unit is one of a series that represents specific moments in history from which students focus on the meanings of landmark events. By studying a crucial turning-point in history, students become aware that choices had to be made by real human beings, that those decisions were the result of specific factors, and that they set in motion a series…

25. GENERAL VIEW FROM SOUTH: LANE TO UNIONTOWN LEADS OUT ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

25. GENERAL VIEW FROM SOUTH: LANE TO UNIONTOWN LEADS OUT OF FOREGROUND TO RIGHT; ORIGINAL BAKEHOUSE IN LEFT CENTER, LEFT OF TREE; MULE BARN OF 1906 IN RIGHT CENTER FOREGROUND; 19TH-CENTURY BARN WITH ADDITIONS AT EXTREME LEFT Photocopy of early 20th-century photograph Collection of Springer Homestead Archives, c/o Gerald Cunningham, Jessup, Maryland - Levi Springer House, Fan Hollow Road, Uniontown, Fayette County, PA

Sacred Cows and Stubborn Mules: The Imperative to Reform the US Code

DTIC Science & Technology

2013-02-14

National Guard have also added specialized domestic military missions like the Chemical, Biological , Radiological and Nuclear (CBRN) Response Enterprise...lists cyber and EMP as exigent future threats, adding that the most predictable future megatrend is empowerment. “Individuals and small groups will...and include a Defense CBRN Response Force (DCRF) and two CBRN Response Elements (CRE). The US Marines also maintain two Chemical, Biological Incident

Development of an Autonomous Navigation Technology Test Vehicle

DTIC Science & Technology

2004-08-01

as an independent thread on processors using the Linux operating system. The computer hardware selected for the nodes that host the MRS threads...communications system design. Linux was chosen as the operating system for all of the single board computers used on the Mule. Linux was specifically...used for system analysis and development. The simple realization of multi-thread processing and inter-process communications in Linux made it a

The Ohio & Erie Canal: Catalyst of Economic Development for Ohio. Teaching with Historic Places.

ERIC Educational Resources Information Center

Ayers, Deborah

In the 19th century, canal boats pulled along by mules carried much cargo. The canal boat was the family business, their livelihood, and their home. In Ohio, these boats glided gracefully along the Ohio and Erie Canal, heavily laden with lumber on its way north to Lake Erie where it was transferred to a lake freighter and sent to Buffalo (New…

Effects of dietary fructose on liver steatosis in overfed mule ducks.

PubMed

Davail, S; Rideau, N; Bernadet, M D; André, J M; Guy, G; Hoo-Paris, R

2005-01-01

Overfeeding of some waterfowl species results in obesity, which is mainly characterized by a dramatic hepatic steatosis induced by strong accumulation of lipids synthesized from dietary glucose in the liver. In mammals, fructose is known to be able to raise plasma triacylglycerol concentrations significantly; consequently, this may induce obesity. The aim of this study was to assess the effect of partial replacement of dietary glucose provided by corn starch with fructose on metabolism and fatty liver production in the Mule ducks. On the basis of 9.5 kg maize (132,920 kJ) given twice a day for 14 days, a supplementation of 9,800 kJ was provided in form of glucose, sucrose or high fructose corn syrup (HFCS: 50 % glucose, 42 % fructose and 8 % other saccharides). Fatty liver weight in ducks fed with glucose supplementation was 499 +/- 21 g. Sucrose or HFCS supplementation brought about a significant increase in liver weight (+ 18.7 % and + 16.3 % vs. glucose supplementation respectively, p < 0.05). These results suggest that the dietary fructose favors the liver steatosis by increasing hepatic lipogenesis. Postprandial plasma insulin concentrations were similar in ducks fed diets with or without fructose, suggesting that the effect of fructose on liver steatosis is not mediated by insulin.

West Foster Creek 2007 Follow-up Habitat Evaluation Procedures (HEP) Report.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ashley, Paul R.

A follow-up habitat evaluation procedures (HEP) analysis was conducted on the West Foster Creek (Smith acquisition) wildlife mitigation site in May 2007 to determine the number of additional habitat units to credit Bonneville Power Administration (BPA) for providing funds to enhance and maintain the project site as partial mitigation for habitat losses associated with construction of Grand Coulee Dam. The West Foster Creek 2007 follow-up HEP survey generated 2,981.96 habitat units (HU) or 1.51 HUs per acre for a 34% increase (+751.34 HUs) above baseline HU credit (the 1999 baseline HEP survey generated 2,230.62 habitat units or 1.13 HUs permore » acre). The 2007 follow-up HEP analysis yielded 1,380.26 sharp-tailed grouse (Tympanuchus phasianellus) habitat units, 879.40 mule deer (Odocoileus hemionus) HUs, and 722.29 western meadowlark (Sturnella neglecta) habitat units. Mule deer and sharp-tailed grouse habitat units increased by 346.42 HUs and 470.62 HUs respectively over baseline (1999) survey results due largely to cessation of livestock grazing and subsequent passive restoration. In contrast, the western meadowlark generated slightly fewer habitat units in 2007 (-67.31) than in 1999, because of increased shrub cover, which lowers habitat suitability for that species.« less

Functional analysis of Normalized Difference Vegetation Index curves reveals overwinter mule deer survival is driven by both spring and autumn phenology

PubMed Central

Hurley, Mark A.; Hebblewhite, Mark; Gaillard, Jean-Michel; Dray, Stéphane; Taylor, Kyle A.; Smith, W. K.; Zager, Pete; Bonenfant, Christophe

2014-01-01

Large herbivore populations respond strongly to remotely sensed measures of primary productivity. Whereas most studies in seasonal environments have focused on the effects of spring plant phenology on juvenile survival, recent studies demonstrated that autumn nutrition also plays a crucial role. We tested for both direct and indirect (through body mass) effects of spring and autumn phenology on winter survival of 2315 mule deer fawns across a wide range of environmental conditions in Idaho, USA. We first performed a functional analysis that identified spring and autumn as the key periods for structuring the among-population and among-year variation of primary production (approximated from 1 km Advanced Very High Resolution Radiometer Normalized Difference Vegetation Index (NDVI)) along the growing season. A path analysis showed that early winter precipitation and direct and indirect effects of spring and autumn NDVI functional components accounted for 45% of observed variation in overwinter survival. The effect size of autumn phenology on body mass was about twice that of spring phenology, while direct effects of phenology on survival were similar between spring and autumn. We demonstrate that the effects of plant phenology vary across ecosystems, and that in semi-arid systems, autumn may be more important than spring for overwinter survival. PMID:24733951

A petrologic comparison of Triassic plutonism in the San Gabriel and Mule Mountains, southern California

NASA Astrophysics Data System (ADS)

Barth, Andrew P.; Tosdal, R. M.; Wooden, J. L.

1990-11-01

Triassic magmatism in the southwest U.S. Cordillera forms a semicontinuous magmatic arc extending from northwestern Nevada to southeastern California. Quartz monzodioritic and quartz monzonitic rocks and associated diorites and granites are widespread in southeastern California, and we suggest that these rocks represent exposure of a structurally deeper part of the Triassic arc, where it was emplaced into comparatively thick Proterozoic crust. Elemental and isotopic data suggest that Triassic quartz monzodiorites and quartz monzonites in the Mule and San Gabriel Mountains were derived from a relatively undepleted, nonradiogenic mafic lithospheric source, with virtually no upper crustal interaction. Very limited data for associated Triassic(?) diorites indicate a wide range in composition and a surprisingly radiogenic isotopic signature. Younger Triassic(?) granites record a strong geochemical signature of interaction with continental crust, including inherited zircon and high initial Sr ratios but comparatively less radiogenic Pb isotopic compositions. The major and trace element geochemistry of Late Triassic plutonic rocks in southeastern California is similar in many respects to alkalic components of the Triassic arc in the Mojave Desert. However, contemporaneous rocks farther north have a calc-alkalic signature, perhaps reflecting the variation in age and composition of lithosphere across which the Triassic arc was constructed.

A petrologic comparison of Triassic plutonism in the San Gabriel and Mule Mountains, southern California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barth, A.P.; Tosdal, R.M.; Wooden, J.L.

1990-11-10

Triassic magmatism in the southwest US Cordillera forms a semicontinuous magmatic arc extending from northwestern Nevada to southeastern California. Quartz monzodioritic and quartz monzonitic rocks and associated diorites and granites are widespread in southeastern California, and the authors suggest that these rocks represent exposure of a structurally deeper part of the Triassic arc, where it was emplaced into comparatively thick Proterozoic crust. Elemental and isotopic data suggest that Triassic quartz monzodiorites and quartz monzonites in the Mule and San Gabriel Mountains were derived from a relatively undepleted, nonradiogenic mafic lithospheric source, with virtually no upper crustal interaction. Very limited datamore » for associated Triassic ( ) diorites indicate a wide range in composition and a surprisingly radiogenic isotopic signature. Younger Triassic( ) granites record a strong geochemical signature of interaction with continental crust, including inherited zircon and high initial Sr ratios but comparatively less radiogenic Pb isotopic compositions. The major and trace element geochemistry of Late Triassic plutonic rocks in southeastern California is similar in many respects to akalic components of the Triassic arc in the Mojave Desert. However, contemporaneous rocks farther north have a calc-alkalic signature, perhaps reflecting the variation in age and composition of lithosphere across which the Triassic arc was constructed.« less

EVALUATION OF A TEST AND CULL STRATEGY FOR REDUCING PREVALENCE OF CHRONIC WASTING DISEASE IN MULE DEER ( ODOCOILEUS HEMIONUS).

PubMed

Wolfe, Lisa L; Watry, Mary Kay; Sirochman, Michael A; Sirochman, Tracey M; Miller, Michael W

2018-04-18

  We evaluated a test and cull strategy for lowering chronic wasting disease (CWD) prevalence in a naturally-infected, free-ranging mule deer ( Odocoileus hemionus) herd wintering in the town of Estes Park, Colorado, USA and in nearby Rocky Mountain National Park. We tested 48-68% of the estimated number of adult (≥1 yr old) deer annually for 5 yr via tonsil biopsy immunohistochemistry (IHC), collecting 1,251 samples from >700 individuals and removing IHC-positive deer. Among males, CWD prevalence during the last 3 yr of selective culling was lower (one-sided Fisher's exact test P=0.014) than in the period prior. In contrast, CWD prevalence among females before culling and after culling were equivalent ( P=0.77). Relatively higher annual testing of males (mean 77%) compared to females (mean 51%) might have contributed to differences seen in responses to management. A more intensive and sustained effort or modified spatial approach might have reduced prevalence more consistently in both sexes. Limitations of this technique in wider management application include cost and labor as well as property access and animal tolerance to repeated capture. However, elements of this approach could potentially be used to augment harvest-based disease management.

Evaluation of repetitive extragenic palindromic-PCR for discrimination of fecal Escherichia coli from humans, and different domestic- and wild-animals.

PubMed

Mohapatra, Bidyut R; Broersma, Klaas; Nordin, Rick; Mazumder, Asit

2007-01-01

The objective of this study was to investigate the potential of repetitive extragenic palindromic anchored polymerase chain reaction (rep-PCR) in differentiating fecal Escherichia coli isolates of human, domestic- and wild-animal origin that might be used as a molecular tool to identify the possible source(s) of fecal pollution of source water. A total of 625 fecal E. coli isolates of human, 3 domestic- (cow, dog and horse) and 7 wild-animal (black bear, coyote, elk, marmot, mule deer, raccoon and wolf) species were characterized by rep-PCR DNA fingerprinting technique coupled with BOX A1R primer and discriminant analysis. Discriminant analysis of rep-PCR DNA fingerprints of fecal E. coli isolates from 11 host sources revealed an average rate of correct classification of 79.89%, and 84.6%, 83.8%, 83.3%, 82.5%, 81.6%, 80.8%, 79.8%, 79.3%, 77.4%, 73.2% and 63.6% of elk, human, marmot, mule deer, cow, coyote, raccoon, horse, dog, wolf and black bear fecal E. coli isolates were assigned to the correct host source. These results suggest that rep-PCR DNA fingerprinting procedures can be used as a source tracking tool for detection of human- as well as animal-derived fecal contamination of water.

Echinococcus granulosus in gray wolves and ungulates in Idaho and Montana, USA.

PubMed

Foreyt, William J; Drew, Mark L; Atkinson, Mark; McCauley, Deborah

2009-10-01

We evaluated the small intestines of 123 gray wolves (Canis lupus) that were collected from Idaho, USA (n=63), and Montana, USA (n=60), between 2006 and 2008 for the tapeworm Echinococcus granulosus. The tapeworm was detected in 39 of 63 wolves (62%) in Idaho, USA, and 38 of 60 wolves (63%) in Montana, USA. The detection of thousands of tapeworms per wolf was a common finding. In Idaho, USA, hydatid cysts, the intermediate form of E. granulosus, were detected in elk (Cervus elaphus), mule deer (Odocoileus hemionus), and a mountain goat (Oreamnos americanus). In Montana, USA, hydatid cysts were detected in elk. To our knowledge, this is the first report of adult E. granulosus in Idaho, USA, or Montana, USA. It is unknown whether the parasite was introduced into Idaho, USA, and southwestern Montana, USA, with the importation of wolves from Alberta, Canada, or British Columbia, Canada, into Yellowstone National Park, Wyoming, USA, and central Idaho, USA, in 1995 and 1996, or whether the parasite has always been present in other carnivore hosts, and wolves became a new definitive host. Based on our results, the parasite is now well established in wolves in these states and is documented in elk, mule deer, and a mountain goat as intermediate hosts.

Using Wireless Sensor Networks and Trains as Data Mules to Monitor Slab Track Infrastructures.

PubMed

Cañete, Eduardo; Chen, Jaime; Díaz, Manuel; Llopis, Luis; Reyna, Ana; Rubio, Bartolomé

2015-06-26

Recently, slab track systems have arisen as a safer and more sustainable option for high speed railway infrastructures, compared to traditional ballasted tracks. Integrating Wireless Sensor Networks within these infrastructures can provide structural health related data that can be used to evaluate their degradation and to not only detect failures but also to predict them. The design of such systems has to deal with a scenario of large areas with inaccessible zones, where neither Internet coverage nor electricity supply is guaranteed. In this paper we propose a monitoring system for slab track systems that measures vibrations and displacements in the track. Collected data is transmitted to passing trains, which are used as data mules to upload the information to a remote control center. On arrival at the station, the data is stored in a database, which is queried by an application in order to detect and predict failures. In this paper, different communication architectures are designed and tested to select the most suitable system meeting such requirements as efficiency, low cost and data accuracy. In addition, to ensure communication between the sensing devices and the train, the communication system must take into account parameters such as train speed, antenna coverage, band and frequency.

Using Wireless Sensor Networks and Trains as Data Mules to Monitor Slab Track Infrastructures

PubMed Central

Cañete, Eduardo; Chen, Jaime; Díaz, Manuel; Llopis, Luis; Reyna, Ana; Rubio, Bartolomé

2015-01-01

Recently, slab track systems have arisen as a safer and more sustainable option for high speed railway infrastructures, compared to traditional ballasted tracks. Integrating Wireless Sensor Networks within these infrastructures can provide structural health related data that can be used to evaluate their degradation and to not only detect failures but also to predict them. The design of such systems has to deal with a scenario of large areas with inaccessible zones, where neither Internet coverage nor electricity supply is guaranteed. In this paper we propose a monitoring system for slab track systems that measures vibrations and displacements in the track. Collected data is transmitted to passing trains, which are used as data mules to upload the information to a remote control center. On arrival at the station, the data is stored in a database, which is queried by an application in order to detect and predict failures. In this paper, different communication architectures are designed and tested to select the most suitable system meeting such requirements as efficiency, low cost and data accuracy. In addition, to ensure communication between the sensing devices and the train, the communication system must take into account parameters such as train speed, antenna coverage, band and frequency. PMID:26131668

2007 Combat Vehicles Conference - Today’s Challenges: Fighting, Sustaining, Modernizing and Transforming

DTIC Science & Technology

2007-10-24

Programs) 1 . FCS MULE .wmv format 2. FCS NLOS Crate Of Fire .wmv format 3. FCS Robotic Convoy .wmv format 4. FCS...included in these sessions will be two “back by popular demand” highlights from previous conferences: 1 ) an update on combat operations in iraq from...15 am - 11:30 am general session general sessiOn - sessiOn 1 : “today’s challenges: fighting, sustaining, modernizing and transforming

Environmental and Water Quality Operational Studies. Environmental Features for Streamside Levee Projects.

DTIC Science & Technology

1985-08-01

Lyon 1976, Lyon and Basile 1979, Lyon and Jenson 1980) showed that windrows over 1.5 ft tall are avoided by mule deer and elk. Thus, brush piles...various State pesticide control authorities. Label directions and general regulations promulgated by these agencies have the power of law and should be...matters, relative attractiveness of alternative baits can vary with season. 606. Like other pesticides , rodenticides are strictly controlled 0 by

Breast Cancer Vaccines Based on Dendritic Cells and the Chemokines

DTIC Science & Technology

1998-07-01

Cancer 50: 289, 1992. 13 . Restifo NP, Esquivel F, Dawakami Y , Yewdell JW, Mule JJ, Rosenberg SA, Bennink JR: Identification of human cancers... 13 . REPORT TYPE AND DATES COVERED Annual (l. Jul 97 - 30 Jun 98) 4. TITLE AND SUBTITLE 5. FUNDING NUMBERS Breast Cancer Vaccines Based on Dendritic...SUPPLEMENTARY NOTES 19981210 109 - 12a. DISTRIBUTION I AVAILABILITY STATEMENT 12b. DISTRIBUTION CODE Approved for public release; distribution unlimited 13

JPRS Report, East Asia, Southeast Asia

DTIC Science & Technology

1988-05-03

Bayan Chief on Impact , Criticism of Efforts ’.’.’.’."’." 39 Election Official Says Postponement Geared To Defeat Rebel Candidates """ŕ"! 43...duplicating machines, 22 typewriters, three televi- sion sets, one video deck, four radio cassettes, two cameras, 23 elephants , 24 horses/mules, 1,451...daw (Navy) vessels are on constant patrol and 132 fish- poaching vessels, 111 black-market vessels and 1,409 fish poachers were seized between 21

Environmental Assessment for the Indoor Training Facility, U.S. Air Force Academy, Colorado Springs, Colorado

DTIC Science & Technology

2010-05-01

Cadet Area. Aluminum would be 35 used on all columns , beam cladding, and window frame trim to provide a visual connection 36 FINAL EA – USAFA INDOOR...and intramural sports played at the Academy. 17 The facility exterior would be white precast concrete, blue polycarbonate, aluminum and 18 glass. The...present there provide a high degree of connectivity between habitat types and 11 maintain migration corridors. Mule deer (Odocoileus hemionus), elk

Multi-Sensory Features for Personnel Detection at Border Crossings

DTIC Science & Technology

2011-07-08

challenging problem. Video sensors consume high amounts of power and require a large volume for storage. Hence, it is preferable to use non- imaging sensors...temporal distribution of gait beats [5]. At border crossings, animals such as mules, horses, or donkeys are often known to carry loads. Animal hoof...field, passive ultrasonic, sonar, and both infrared and visi- ble video sensors. Each sensor suite is placed along the path with a spacing of 40 to

Private Rogers L. Taylor: Prisoner of the Japanese

DTIC Science & Technology

2015-04-01

cooking , its body closely resembled that of a human baby. Other soldiers recall their memories regarding the local fare on Bataan. Lajzer recounted...Horse meat stunk so bad it was revolting. The cooks would boil it and then fry it over an open fire so it could be eaten. … Believe me, mules...gathering wood and water for cooking but the worst was the burial detail, which Taylor begrudgingly performed. This is not a detail he spoke of

Long-term outcome associated with intratumoral chemotherapy with cisplatin for cutaneous tumors in equidae: 573 cases (1995-2004).

PubMed

Théon, Alain P; Wilson, W David; Magdesian, K Gary; Pusterla, Nicola; Snyder, Jack R; Galuppo, Larry D

2007-05-15

To determine outcome associated with cutaneous tumors treated via intratumoral chemotherapy with cisplatin and identify risk factors affecting local tumor control and complications in equidae. Retrospective case series. 573 equidae with 630 cutaneous tumors. Medical records of horses, mules, donkeys, and ponies with cutaneous tumors treated via intratumoral chemotherapy with cisplatin were analyzed. 549 horses, 13 mules, 8 donkeys, and 3 ponies with 630 histologically confirmed cutaneous tumors were included. Tumors included sarcoids (n = 409), squamous cell carcinomas (151), soft tissue sarcomas (28), cutaneous lymphomas (26), and melanomas (16). Overall cure rate, defined as local control at 4 years, was 93.3%. For all tumor stages combined, cure rates after 1 course of treatment were 96.3% for sarcoids, 96% for lymphomas, 88% for squamous cell carcinomas, 85% for soft tissue sarcomas, and 81% for melanomas. Treatment protocol, tumor stage, and prior treatment were significant prognostic factors for tumor control. Treatment efficacy was lower for large tumors, those with gross postoperative residual disease, and those that had been treated previously with other modalities. Treatment was well tolerated. Local reactions were more likely to occur and to be more severe after the third and fourth treatment sessions. Results confirmed the value of intratumoral chemotherapy with cisplatin for treatment of cutaneous tumors in equidae. The results cannot be extrapolated to other formulations of cisplatin or other protocols that might be used.

KRIBB11 accelerates Mcl-1 degradation through an HSF1-independent, Mule-dependent pathway in A549 non-small cell lung cancer cells.

PubMed

Kang, Min-Jung; Yun, Hye Hyeon; Lee, Jeong-Hwa

2017-10-21

The Bcl-2 family protein, Mcl-1 is known to have anti-apoptotic functions, and depletion of Mcl-1 by cellular stresses favors the apoptotic process. Moreover, Mcl-1 levels are frequently increased in various cancer cells, including non-small cell lung cancer (NSCLC), and is implicated in resistance to conventional chemotherapy and in cancer metastasis. In this study, we demonstrated that KRIBB11 accelerates the proteasomal degradation of Mcl-1 in the NSCLC cell line, A549. While KRIBB11 is an inhibitor of HSF1, we found that KRIBB11 induced Mcl-1 degradation in an HSF1-independent manner. Furthermore, this process was triggered via increase ubiquitination by the E3 ligase, Mule, rather than via de-ubiquitination by USP9X. Additionally, we found that Mcl-1 levels were only transiently reduced by KRIBB11: Mcl-1 levels were gradually restored as KRIBB11 activity diminished. However, we found that this effect was blocked in BIS (Bcl-2 interacting cell death suppressor, also called BAG3)-depleted cells, and that BIS prevents Mcl-1 from undergoing HSP70-driven proteasomal degradation, through an interaction with HSP70. Taken together, our results suggest that targeting Mcl-1 with KRIBB11 treatment, while simultaneously downregulating BIS, could be a therapeutic strategy in NSCLC. Copyright © 2017 Elsevier Inc. All rights reserved.

Magnetic properties of a new obsidian source, west Antelope Creek, Grant County, New Mexico

NASA Astrophysics Data System (ADS)

Sternberg, R. S.; Samuels, R.; Feinberg, J. M.; Shackley, M. S.

2013-12-01

This work is part of a Keck Geology Consortium project on characterizing obsidian sources in New Mexico using magnetic and geochemical properties. We collected over 3,000 samples, many of which were georeferenced, from 10 obsidian sources at three locales - Mule creek, Mt. Taylor, and Valles Caldera. One of the Mule Creek sources, herein called the west Antelope Creek (wAC) source, was previously unknown. The 143 samples collected at this source covered about 1 km2, but were not individually georeferenced. We plan to characterize the magnetic and chemical properties of this source to see if it is distinguishable from other nearby sources and useful for provenancing archaeological obsidians. Initial measurements on 34 specimens from 20 samples show NRM values range from 1-80 Am2/kg, and low-field susceptibilities range from 1.2-96 x 10-8 mass specific SI units. When there were two specimens from the same sample, results were in good agreement. The measurements define a rather broad field in NRM-susceptibility space compared to other Southwestern sources examined to date, and a considerably larger field than from the nearby Antelope Creek (AC) source. The previously measured NRM and susceptibility values from AC are all in the high end on both dimensions of the wAC field, so that these fields overlap but in many cases could be distinguished.

Development of a range-extended electric vehicle powertrain for an integrated energy systems research printed utility vehicle

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chambon, Paul; Curran, Scott; Huff, Shean

Rapid vehicle and powertrain development has become essential to for the design and implementation of vehicles that meet and exceed the fuel efficiency, cost, and performance targets expected by today’s consumer while keeping pace with reduced development cycle and more frequent product releases. Advances in large-scale additive manufacturing have provided the means to bridge hardware-in-the-loop (HIL) experimentation and preproduction mule chassis evaluation, recently. Our paper details the accelerated development of a printed range-extended electric vehicle (REEV) by Oak Ridge National Laboratory, by paralleling hardware-in-the-loop development of the powertrain with rapid chassis prototyping using big area additive manufacturing (BAAM). BAAM’s abilitymore » to accelerate the mule vehicle development from computer-aided design to vehicle build is explored. The use of a hardware-in-the-loop laboratory is described as it is applied to the design of a range-extended electric powertrain to be installed in a printed prototype vehicle. Furthermore, the integration of the powertrain and the opportunities and challenges it presents are described in this work. A comparison of offline simulation, HIL and chassis rolls results is presented to validate the development process. Chassis dynamometer results for battery electric and range extender operation are analyzed to show the benefits of the architecture.« less

Development of a range-extended electric vehicle powertrain for an integrated energy systems research printed utility vehicle

DOE PAGES

Chambon, Paul; Curran, Scott; Huff, Shean; ...

2017-01-29

Rapid vehicle and powertrain development has become essential to for the design and implementation of vehicles that meet and exceed the fuel efficiency, cost, and performance targets expected by today’s consumer while keeping pace with reduced development cycle and more frequent product releases. Advances in large-scale additive manufacturing have provided the means to bridge hardware-in-the-loop (HIL) experimentation and preproduction mule chassis evaluation, recently. Our paper details the accelerated development of a printed range-extended electric vehicle (REEV) by Oak Ridge National Laboratory, by paralleling hardware-in-the-loop development of the powertrain with rapid chassis prototyping using big area additive manufacturing (BAAM). BAAM’s abilitymore » to accelerate the mule vehicle development from computer-aided design to vehicle build is explored. The use of a hardware-in-the-loop laboratory is described as it is applied to the design of a range-extended electric powertrain to be installed in a printed prototype vehicle. Furthermore, the integration of the powertrain and the opportunities and challenges it presents are described in this work. A comparison of offline simulation, HIL and chassis rolls results is presented to validate the development process. Chassis dynamometer results for battery electric and range extender operation are analyzed to show the benefits of the architecture.« less

Evaluation of road expansion and connectivity mitigation for wildlife in southern California

USGS Publications Warehouse

Alonso, Robert S.; Lyren, Lisa M.; Boydston, Erin E.; Haas, Christopher D.; Crooks, Kevin R.

2014-01-01

We designed a remote-camera survey to study how the expansion of California State Route 71 (CA-71) and implementation of connectivity mitigation affected the use of underpasses by large mammals in southern California. Based on detections by cameras, the use of underpasses by bobcats (Lynx rufus) was higher within the area of expansion and mitigation after construction than before, but there was no difference in use of underpasses in the impact zone compared to the control zone before or after construction. Use of underpasses by coyotes (Canis latrans) was higher in the control zone than in the impact zone, but there was no difference in use before and after construction. Small numbers of detections of mule deer (Odocoileus hemionus) at only a few underpasses precluded comparison between control and impact zones. However, a comparison of use before and after construction revealed that use of underpasses by mule deer was slightly higher post-construction. We cannot fully attribute increased detections post-construction to mitigative efforts, because other factors, such as availability of habitat, urbanization, or demography, also may have influenced use of underpasses along CA-71. Nonetheless, even with the expansion of the freeway and subsequent increase in volume of traffic, mitigative structures along CA-71 did allow for continued movement and, hence, connectivity across the roadway for large mammals.

KSC-08pd2637

NASA Image and Video Library

2008-09-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility at NASA’s Kennedy Space Center, the Multi-Use Logistic Equipment, or MULE, carrier is moved toward the payload canister. The carrier is one of four associated with the STS-125 mission to service the Hubble Space Telescope. It will be installed in the payload canister for transfer to Launch Pad 39A. At the pad, all the carriers will be loaded into space shuttle Atlantis’ payload bay. Launch of Atlantis is targeted for Oct. 10. Photo credit: NASA/Jack Pfaller

KSC-08pd2636

NASA Image and Video Library

2008-09-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility at NASA’s Kennedy Space Center, an overhead crane lifts the Multi-Use Logistic Equipment, or MULE, carrier. The carrier is one of four associated with the STS-125 mission to service the Hubble Space Telescope. It will be installed in the payload canister for transfer to Launch Pad 39A. At the pad, all the carriers will be loaded into space shuttle Atlantis’ payload bay. Launch of Atlantis is targeted for Oct. 10. Photo credit: NASA/Jack Pfaller

KSC-08pd2638

NASA Image and Video Library

2008-09-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility at NASA’s Kennedy Space Center, the Multi-Use Logistic Equipment, or MULE, carrier is moved toward the payload canister. The carrier is one of four associated with the STS-125 mission to service the Hubble Space Telescope. It will be installed in the payload canister for transfer to Launch Pad 39A. At the pad, all the carriers will be loaded into space shuttle Atlantis’ payload bay. Launch of Atlantis is targeted for Oct. 10. Photo credit: NASA/Jack Pfaller

KSC-08pd2635

NASA Image and Video Library

2008-09-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility at NASA’s Kennedy Space Center, an overhead crane lifts the Multi-Use Logistic Equipment, or MULE, carrier. The carrier is one of four associated with the STS-125 mission to service the Hubble Space Telescope. It will be installed in the payload canister for transfer to Launch Pad 39A. At the pad, all the carriers will be loaded into space shuttle Atlantis’ payload bay. Launch of Atlantis is targeted for Oct. 10. Photo credit: NASA/Jack Pfaller

A Disruption of ctpA Encoding Carboxy-Terminal Protease Attenuates Burkholderia mallei and Induces Partial Protection in CD1 Mice

DTIC Science & Technology

2008-06-03

etiologic agent of glanders in solipeds (horses, mules and donkeys), and incidentally in carnivores and humans. Little is known about the molecular...disintegrated cell envelopes. Furthermore, relative to the wild type, the ctpA mutant displayed slower growth in vitro and less ability to survive in...IgG2a and were partially protected against chal- lenge with wild type B. mallei ATCC 23344. These findings suggest that CtpA regulates in vitro growth

Environmental Assessment for the Construction and Operation of a New Facility to House the Center for Character and Leadership Development Program

DTIC Science & Technology

2010-06-30

OF FORMULATION OF ALTERNATIVES A series of meetings between a jury of advisors and stakeholders resulted in two proposals (Alternative 1 and...following: mule and white-tail deer, black bear, mountain lion , small-footed bat, least ch ipmunk, several mouse species, cottontail rabbit, red fox ...Page I 21 Table 3-2 National and Colorado Ambient Air Quality Standards Pollutant National Colorado Carbon Monoxide (CO) 8-hour average 9 ppm 10 mg

Cultural Resource Survey for the Consolidated Space Operations Center Project Near Colorado Springs, El Paso County, Colorado.

DTIC Science & Technology

1982-01-01

fauna, to attract hunters prehistorically. I But as this area was not prime habitable land for humans, it probably also did not support large herds ...Rocky Mountain areas. The Archaic people were less dependent on herd movement, thus their socio-economic systems changed. This adaptation to a changing...coyotes, skunks, ground squirrels, pocket gophers, wolves, mule deer, white- tail deer, beaver, and porcupine (Larsen 1981; Goodlng 1977:4; Eddy 1981:7

Effects of dietary protein level during rearing period and age at overfeeding on magret and foie gras quality in male mule ducks.

PubMed

Arroyo, Julien; Molette, Caroline; Lavigne, Franck; Margetyal, Carole; Amador, Olivier; Dubois, Jean-Pierre; Fortun-Lamothe, Laurence

2018-03-01

The aim of this trial was to study the effects of dietary protein content during the rearing period on the performance of mule ducks, according to age at overfeeding (O). Ducks (n = 612) were divided into four groups differing in the protein content in the diet offered during the starting period (S, 0-20 days; S l vs. S h : 150 vs. 175 g/kg crude protein (CP)) and growing-finishing period (GF; 21-67 or 81 days, depending on age at O; GF l vs. GF h : 133 vs. 152 g/kg CP). The relative weight of pectoral muscle was lower when ducks were fed a low protein diet during S (-5%, P < 0.01) or GF period (-6%, P < 0.001) at 68 days and higher in ducks of the S l GF h group (+6%; P < 0.05) at 82 days. Both foie gras and magret weights fell when ducks were fed S l or GF l (P < 0.05 and < 0.01). Mortality during the O period was higher in ducks fed the S l diet and overfed at late age (7.4% vs. 0%; P < 0.01). In conclusion, a reduction in the dietary protein supply should be recommended only during the GF period for ducks overfed at a late age. © 2017 Japanese Society of Animal Science.

CAPTURE OF FREE-RANGING MULE DEER (ODOCOILEUS HEMIONUS) WITH A COMBINATION OF MEDETOMIDINE, AZAPERONE, AND ALFAXALONE.

PubMed

Mathieu, Amélie; Caulkett, Nigel; Stent, Patrick M; Schwantje, Helen M

2017-04-01

The combination of medetomidine, azaperone, and alfaxalone has been successfully used to anesthetize captive white-tailed deer ( Odocoileus virginianus ). This same combination was utilized to immobilize free-ranging female mule deer ( Odocoileus hemionus ; MD) in urban and nonurban environments (14 urban MD, 14 nonurban MD) in British Columbia, Canada. Physiologic data were collected to assess the safety and reliability of this drug combination under field conditions. Each deer received estimated dosages of 0.15 mg/kg medetomidine, 0.2 mg/kg azaperone, and 0.5 mg/kg alfaxalone intramuscularly via a remote darting system. Inductions were calm and rapid (mean time to sternal recumbency: urban MD, 6.4±2.2 min; nonurban MD, 8.2±4.1 min). Supplemental drugs were required to induce lateral recumbency in five deer, four of which had experienced initial dart failure (mean time to lateral recumbency: urban MD, 8.5±3.8 min; nonurban MD, 18.7±16.5 min). Recoveries were smooth and uneventful (time to standing: urban MD, 12.5±3.4 min; nonurban MD, 9.0±3.5 min) for all but one debilitated nonurban MD that died shortly after atipamezole administration (at five times the medetomidine dose). The major side effects of the combination were hypoxemia and hypercapnia. The combination of medetomidine, azaperone, and alfaxalone proved suitable for the immobilization of urban and nonurban free-ranging MD.

Colic caused by Panicum maximum toxicosis in equidae in northern Brazil.

PubMed

Cerqueira, Valíria D; Riet-Correa, Gabriela; Barbosa, José D; Duarte, Marcos D; Oliveira, Carlos M C; de Oliveira, Carlos A; Tokarnia, Carlos; Lee, Stephen T; Riet-Correa, Franklin

2009-11-01

In the Amazon region of northern Brazil, Panicum maximum cultivars Mombaça, Tanzânia, and Massai cause severe colic and death in horses and mules. The disease occurs in the rainy season, when sprouting pastures are grazed by equidae. In the 8 separate disease outbreaks studied, a total of 52 out of 153 equidae were affected, including 19 that died (10 mules and 9 horses). Clinical signs were colic and abdominal dilatation, with a clinical manifestation period of 12 hr to 4 days. Serum activities of gamma-glutamyl transferase and aspartate aminotransferase were within reference intervals; however, serum urea nitrogen and creatinine concentrations were occasionally elevated. The primary gross and histologic lesions were observed in the digestive system. The stomach, small intestine, and large intestine had severe hemorrhages and occasional mucosal erosions and ulcerations. Ulceration and hemorrhage of the urinary bladder were rarely observed. Histologic examination revealed diffuse lymphoplasmacytic gastritis and enteritis with severe congestion, hemorrhage, and occasional epithelial necrosis and ulceration. Lymphocellular necrosis was occasionally observed within gut-associated lymphoid tissue. Tubular nephrosis occurred in some animals. Degeneration and occasional necrosis of bile duct epithelial cells and degeneration of hepatocytes were observed in the liver. Toxic pastures were negative for diosgenin- and yamogenin-based saponins, and oxalate concentrations were within reference intervals for the species. The toxin or toxins causing disease and the reason for the toxicity of the plant in the northern region are unknown.

Karst show caves - how DTN technology as used in space assists automatic environmental monitoring and tourist protection - experiment in Postojna cave

NASA Astrophysics Data System (ADS)

Gabrovšek, F.; Grašič, B.; Božnar, M. Z.; Mlakar, P.; Udén, M.; Davies, E.

2013-10-01

The paper presents an experiment demonstrating a novel and successful application of Delay- and Disruption-Tolerant Networking (DTN) technology for automatic data transfer in a karst cave Early Warning and Measuring System. The experiment took place inside the Postojna Cave in Slovenia, which is open to tourists. Several automatic meteorological measuring stations are set up inside the cave, as an adjunct to the surveillance infrastructure; the regular data transfer provided by the DTN technology allows the surveillance system to take on the role of an Early Warning System (EWS). One of the stations is set up alongside the railway tracks, which allows the tourist to travel inside the cave by train. The experiment was carried out by placing a DTN "data mule" (a DTN-enabled computer with WiFi connection) on the train and by upgrading the meteorological station with a DTN-enabled WiFi transmission system. When the data mule is in the wireless drive-by mode, it collects measurement data from the station over a period of several seconds as the train passes the stationary equipment, and delivers data at the final train station by the cave entrance. This paper describes an overview of the experimental equipment and organisation allowing the use of a DTN system for data collection and an EWS inside karst caves where there is a regular traffic of tourists and researchers.

Karst show caves - how DTN technology as used in space assists automatic environmental monitoring and tourist protection - experiment in Postojna Cave

NASA Astrophysics Data System (ADS)

Gabrovšek, F.; Grašič, B.; Božnar, M. Z.; Mlakar, P.; Udén, M.; Davies, E.

2014-02-01

The paper presents an experiment demonstrating a novel and successful application of delay- and disruption-tolerant networking (DTN) technology for automatic data transfer in a karst cave early warning and measuring system. The experiment took place inside the Postojna Cave in Slovenia, which is open to tourists. Several automatic meteorological measuring stations are set up inside the cave, as an adjunct to the surveillance infrastructure; the regular data transfer provided by the DTN technology allows the surveillance system to take on the role of an early warning system (EWS). One of the stations is set up alongside the railway tracks, which allows the tourist to travel inside the cave by train. The experiment was carried out by placing a DTN "data mule" (a DTN-enabled computer with WiFi connection) on the train and by upgrading the meteorological station with a DTN-enabled WiFi transmission system. When the data mule is in the wireless drive-by mode, it collects measurement data from the station over a period of several seconds as the train without stopping passes the stationary equipment, and delivers data at the final train station by the cave entrance. This paper describes an overview of the experimental equipment and organization allowing the use of a DTN system for data collection and an EWS inside karst caves where there is regular traffic of tourists and researchers.

Seroprevalence and Risk Factors for Theileria equi Infection in Equines from Khyber Pakhtunkhwa Province, Pakistan

PubMed Central

AFRIDI, Muhammad Jamal Khan; MIAN, Abdul Hafeez; SAQIB, Muhammad; ABBAS, Ghazanfar; ALI, Javid; MANSOOR, Muhammad Khalid; SIAL, Awais ur Rahman; RASHEED, Imaad; HUSSAIN, Muhammad Hammad

2017-01-01

Background: Theileria equi is a tick borne protozoan parasite which causes piroplasmosis among equines worldwide. The present study was aimed to determine seroprevalence of T. equi in donkeys, horses, and mules from two equine populated districts (Peshawar and Charsadda) of Khyber Pakhtunkhwa (KPK), Pakistan. Methods: A total of 393 equine (195 horses, 194 donkeys and 4 mules) serum samples were collected from five and four randomly selected localities in Charsadda (n = 193) and Peshawar (n = 200), respectively. The presence of antibodies to T. equi was determined using a commercially available competitive enzyme-linked immunosorbent assay. Results: An overall seroprevalence of 38.2% (n=150) was observed among all the tested animals suggesting a higher seropositivity among equids belonging to Charsada (50.3%) as compared to Peshawar (27.5%). Binary logistic regression analysis revealed that being a donkey (OR 2.94), having tick infestation (OR 4.32), history of voiding red (i.e., blood containing) urine (OR 3.97) and anemia (OR 2.1) were the factors significantly associated with the seroprevalence of T. equi. For animals with higher anti-T. equi antibody titers, a strong association of seroprevalence for T. equi was recorded with species, age, sex, tick infestation, anemia and history of hematuria. Conclusion: The present study indicates a high level of exposure of working equids to T. equi in KPK region, Pakistan. Future studies should focus on tick vector identification and other factors responsible for spread of the disease. PMID:29317885

Radioecology of natural systems. Fifteenth annual progress report, August 1, 1976--July 31, 1977. [Plutonium transport in terrestrial ecosystems at Rocky Flats Plant with emphasis on biological effects on mule deer and coyotes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Whicker, F.W.

1977-08-01

This report summarizes project activities during the period August 1, 1976 through July 31, 1977. Four major areas of effort are reported, namely plutonium behavior in a terrestrial ecosystem at Rocky Flats, mule deer and coyote studies at Rocky Flats, ecological consequences of transuranics in the terrestrial environment, and lead geochemistry of an alpine lake ecosystem. Much of the first area of effort involved the synthesis of data and preparation of manuscripts, although some new data are reported on plutonium levels in small mammals, plant uptake of plutonium from contaminated soil, and plutonium deposition rates on macroplot 1. The mulemore » deer studies generated a substantial body of new information which will permit quantitative assessment of plutonium dispersion by deer that utilize contaminated areas. These studies involve population dynamics, movement and use patterns, food habits, ingestion rates of contaminated soil and vegetation and plutonium burdens of deer tissues. A related study of coyote food habits in summer at Rocky Flats is reported. A manuscript dealing with the question of ecological effects of transuranics was prepared. This manuscript incorporates data from Rocky Flats on characteristics of natural populations which occupy ecologically similar areas having differing levels of plutonium contamination. The lead geochemistry studies continued to generate new data but the data are not yet reported.« less

Mineral licks: motivational factors for visitation and accompanying disease risk at communal use sites of elk and deer.

PubMed

Lavelle, Michael J; Phillips, Gregory E; Fischer, Justin W; Burke, Patrick W; Seward, Nathan W; Stahl, Randal S; Nichols, Tracy A; Wunder, Bruce A; VerCauteren, Kurt C

2014-12-01

Free-ranging cervids acquire most of their essential minerals through forage consumption, though occasionally seek other sources to account for seasonal mineral deficiencies. Mineral sources occur as natural geological deposits (i.e., licks) or as anthropogenic mineral supplements. In both scenarios, these sources commonly serve as focal sites for visitation. We monitored 11 licks in Rocky Mountain National Park, north-central Colorado, using trail cameras to quantify daily visitation indices (DVI) and soil consumption indices (SCI) for Rocky Mountain elk (Cervus elaphus) and mule deer (Odocoileus hemionus) during summer 2006 and documented elk, mule deer, and moose (Alces alces) visiting licks. Additionally, soil samples were collected, and mineral concentrations were compared to discern levels that explain rates of visitation. Relationships between response variables; DVI and SCI, and explanatory variables; elevation class, moisture class, period of study, and concentrations of minerals were examined. We found that DVI and SCI were greatest at two wet, low-elevation licks exhibiting relatively high concentrations of manganese and sodium. Because cervids are known to seek Na from soils, we suggest our observed association of Mn with DVI and SCI was a likely consequence of deer and elk seeking supplemental dietary Na. Additionally, highly utilized licks such as these provide an area of concentrated cervid occupation and interaction, thus increasing risk for environmental transmission of infectious pathogens such as chronic wasting disease, which has been shown to be shed in the saliva, urine, and feces of infected cervids.

Using remotely sensed indices of primary productivity to evaluate large mammal abundance and movement in the arid Southwestern United States

NASA Astrophysics Data System (ADS)

Stoner, D.; Edwards, T.; Sexton, J. O.; Nagol, J.; Sims, A.; Ironside, K.; Choate, D.; Longshore, K.; Anand, A.; Mattson, D.

2013-12-01

Southwestern ecoregions are marked by topographic and climatic variability, which facilitates the coexistence of large herbivores exploiting different dietary niches. Mountain ungulates buffer this variability through physiological and behavioral adaptations such as fat accumulation and seasonal migrations. However, projected climatic shifts imply changes in vegetation biomass and phenology, and therefore mammalian distributions. Here we evaluate how the distribution of primary productivity and phenological rhythms influence abundance and seasonal movements of three widely distributed ungulate species and their principal predator. We used spatio-temporal patterns in the Normalized Difference Vegetation Index (NDVI) derived from MODerate-resolution Imaging Spectrometer (MODIS) measurements at 250-m, daily resolution to explain spatial variability in the abundance of mule deer, elk, and bighorn sheep. Ungulate population response to NDVI was assessed using annual survey data collected by state wildlife agencies with jurisdiction on and around the Colorado Plateau ecoregion. We used NDVI-ungulate relationships to evaluate the spatial requirements and potential densities of cougars; a predator whose diet, density, and distribution is closely tied to these species. Cougar location data were combined from nine radio-telemetry studies conducted over a range of climatic conditions. Focal ungulates demonstrated differing responses to patterns in NDVI. Mule deer abundance corresponded to the timing of green-up (late spring), elk abundance correlated best with peak green biomass (July-Aug), and bighorn showed no relationship to NDVI. Seasonal movements also differed, with deer migrating between distinct summer and winter ranges; bighorn residing on annual ranges, and elk demonstrating a mixed pattern of residency and migration. Cougar movements did not correspond to phenology per se, but home range size and diet diversity varied inversely with NDVI. Projected shifts in the timing and amount of precipitation suggest three considerations for large mammal conservation in the Southwest. First, being tied to June NDVI, mule deer distribution is likely to track areas defined by relatively early growing seasons, whereas elk abundance is likely to increase in response to enhanced summer precipitation. Second, in mesic environments bighorn sheep are both poor competitors and susceptible to predation. To the extent that bighorn sheep are forced to share ranges with deer or elk, they may be adversely affected by changing climate. Lastly, shifts in ungulate abundance may lead cougars to switch prey in some localities, or contract from the drier portions of their current range as energetic costs rise beyond threshold values.

Hybrid Vehicle Program. Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1984-06-01

This report summarizes the activities on the Hybrid Vehicle Program. The program objectives and the vehicle specifications are reviewed. The Hybrid Vehicle has been designed so that maximum use can be made of existing production components with a minimum compromise to program goals. The program status as of the February 9-10 Hardware Test Review is presented, and discussions of the vehicle subsystem, the hybrid propulsion subsystem, the battery subsystem, and the test mule programs are included. Other program aspects included are quality assurance and support equipment. 16 references, 132 figures, 47 tables.

Localization with Sparse Acoustic Sensor Network Using UAVs as Information-Seeking Data Mules

DTIC Science & Technology

2013-05-01

technique to differentiate among several sources. 2.2. AoA Estimation AoA Models. The kth of NAOA AoA sensors produces an angular measurement modeled...squares sense. θ̂ = arg min φ 3∑ i=1 ( ̂τi0 − eTφ ri )2 (9) The minimization was done by gridding the one-dimensional angular space and finding the optimum...Latitude E5500 laptop running FreeBSD and custom Java applications to process and store the raw audio signals. Power Source: The laptop was powered for an

VLSI (Very Large Scale Integration) Design Tools, Reference Manual, Release 3.0.

DTIC Science & Technology

1985-08-01

generators/mult prior to running mult. The generated layout is output in directory 1ca in caesar cells with names of the form "caesarame*oca. Mut is a cft ...vlsa) spice(1.vlsi), User’s Guide to AML VLSI Dodgen Tools Reference Manual, UW/NW VLSI Consortium, University of Washington, (Christopher Terman, MIT...of the form ’caesarname..ca. Muls is a cft -based program and therefore also produces *.bd fiIls ’Caesaramew may not begin with the string mule. The

KSC-08pd3257

NASA Image and Video Library

2008-10-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility, or PHSF, at NASA's Kennedy Space Center in Florida, a crane lowers the Multi-Use Lightweight Equipment, or MULE, carrier toward a stand. The carrier contains hardware for the STS-125 Hubble Space Telescope servicing mission that has been returned to the PHSF to await a new launch date for the mission. Atlantis' targeted launch on Oct. 14 was delayed when a system that transfers science data from the orbiting observatory to Earth malfunctioned on Sept. 27. The new target launch date is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd3258

NASA Image and Video Library

2008-10-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility, or PHSF, at NASA's Kennedy Space Center in Florida, a crane lowers the Multi-Use Lightweight Equipment, or MULE, carrier toward a stand. The carrier contains hardware for the STS-125 Hubble Space Telescope servicing mission that has been returned to the PHSF to await a new launch date for the mission. Atlantis' targeted launch on Oct. 14 was delayed when a system that transfers science data from the orbiting observatory to Earth malfunctioned on Sept. 27. The new target launch date is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd3256

NASA Image and Video Library

2008-10-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility, or PHSF, at NASA's Kennedy Space Center in Florida, a crane moves the Multi-Use Lightweight Equipment, or MULE, carrier toward a stand. The carrier contains hardware for the STS-125 Hubble Space Telescope servicing mission that has been returned to the PHSF to await a new launch date for the mission. Atlantis' targeted launch on Oct. 14 was delayed when a system that transfers science data from the orbiting observatory to Earth malfunctioned on Sept. 27. The new target launch date is under review. Photo credit: NASA/Kim Shiflett

KSC-08pd3259

NASA Image and Video Library

2008-10-17

CAPE CANAVERAL, Fla. - In the Payload Hazardous Servicing Facility, or PHSF, at NASA's Kennedy Space Center in Florida, a crane lowers the Multi-Use Lightweight Equipment, or MULE, carrier onto a stand. The carrier contains hardware for the STS-125 Hubble Space Telescope servicing mission that has been returned to the PHSF to await a new launch date for the mission. Atlantis' targeted launch on Oct. 14 was delayed when a system that transfers science data from the orbiting observatory to Earth malfunctioned on Sept. 27. The new target launch date is under review. Photo credit: NASA/Kim Shiflett

Chronic Wasting Disease

USGS Publications Warehouse

Richards, Bryan

2007-01-01

Chronic wasting disease (CWD) is an always-fatal, neurological illness occurring in North American cervids (members of the deer family), including white-tailed deer, mule deer, elk and moose. Since its discovery in 1967, CWD has spread geographically and increased in prevalence locally. CWD is contagious; it can be transmitted freely within and among free-ranging populations. It is likely that diseased animals can transmit CWD to healthy animals long before they become clinically ill. Managing CWD in free-ranging populations is extremely difficult, therefore preventative measures designed to reduce the chance for disease spread are critically important.

Inventory and analysis of natural vegetation and related resources from space and high altitude photography

NASA Technical Reports Server (NTRS)

Poulton, C. E.

1972-01-01

A multiple sampling technique was developed whereby spacecraft photographs supported by aircraft photographs could be used to quantify plant communities. Large scale (1:600 to 1:2,400) color infrared aerial photographs were required to identify shrub and herbaceous species. These photos were used to successfully estimate a herbaceous standing crop biomass. Microdensitometry was used to discriminate among specific plant communities and individual plant species. Large scale infrared photography was also used to estimate mule deer deaths and population density of northern pocket gophers.

Identifying environmental features for land management decisions

NASA Technical Reports Server (NTRS)

1981-01-01

The benefits of changes in management organization and facilities for the Center for Remote Sensing and Cartography in Utah are reported as well as interactions with and outreach to state and local agencies. Completed projects are described which studied (1) Unita Basin wetland/land use; (2) Davis County foothill development; (3) Farmington Bay shoreline fluctuation; (4) irrigation detection; and (5) satellite investigation of snow cover/mule deer relationships. Techniques developed for composite computer mapping, contrast enhancement, U-2 CIR/LANDSAT digital interface; factor analysis, and multivariate statistical analysis are described.

Assessment of Chlamydia psittaci Shedding and Environmental Contamination as Potential Sources of Worker Exposure throughout the Mule Duck Breeding Process

PubMed Central

Hulin, V.; Bernard, P.; Vorimore, F.; Aaziz, R.; Cléva, D.; Robineau, J.; Durand, B.; Angelis, L.

2015-01-01

Chlamydia psittaci is an obligate intracellular bacterium responsible for avian chlamydiosis, otherwise known as psittacosis, a zoonotic disease that may lead to severe atypical pneumonia. This study was conducted on seven mule duck flocks harboring asymptomatic birds to explore the circulation and persistence of C. psittaci during the entire breeding process and assess the potential sources of worker exposure. Cloacal swabs and air samples were taken on each occasion requiring humans to handle the birds. In parallel, environmental samples, including dust, water, and soil, were collected. Specific real-time PCR analyses revealed the presence of C. psittaci in all flocks but with three different shedding patterns involving ducks about the age of 4, 8, and 12 weeks with heavy, moderate, and low excretion levels, respectively. Air samples were only positive in flocks harboring heavy shedders. Dust in flocks with heavy or moderate shedders carried chlamydial loads strongly associated with the loads detected in avian and soil samples. Environmental contamination, significantly correlated with shedding dynamics, was considered to be the most probable source of exposure. The high prevalence of bacteriophage Chp1 in all flocks, mostly jointly present with chlamydia, suggests an important factor in C. psittaci persistence, thus creating a greater risk for humans. A survey conducted in these flocks regarding farming practices and activities showed that disinfection seems to be the most promising practice for reducing C. psittaci prevalence in ducks and that the place and the duration of action during operations seem to be potential risk factors. Strict adherence to good practices is strongly recommended. PMID:26712548

Establishment of a definitive protocol for the diagnosis and management of body packers (drug mules).

PubMed

Mandava, Nageswara; Chang, Richard S; Wang, John H; Bertocchi, Michael; Yrad, Jonathan; Allamaneni, Shyam; Aboian, Edouard; Lall, Malini H; Mariano, Rosalind; Richards, Neil

2011-02-01

'Mules' or body packers are people who transport illegal drugs by packet ingestion into the gastrointestinal tract. These people are otherwise healthy and their management should maintain minimal morbidity. In this study, experience with body packers is presented and an algorithm for conservative and surgical management is provided. The clinical patient database for all body packer admissions at Mary Immaculate Hospital of the Caritas Health Care Inc. from 1993 to 2005 was interrogated. 56 patients (4.5%) required admission out of a total of 1250 subjects confirmed to be body packers and apprehended by United State Customs officials at JFK International Airport, New York. The retrieved patient data were analysed retrospectively. 70% of the body packers were men, with a male to female ratio of 2.8 to 1. The mean age was 33 years and 52% were from Columbia. Heroin was the most common illegally transported substance (73%). 25 patients (45%) required surgical intervention, whereas 31 patients (55%) were successfully managed conservatively. Indications for intervention included: bowel obstruction, packet rupture/toxicity, and delayed progression of packet transit on conservative management. Multiple intraoperative manoeuvres were used to remove the foreign bodies: gastrotomy, enterotomy and colotomy. Wound infection was the most common complication and is associated with distal enterotomy and colotomy. Men were more likely to present as body packers than women. Proximal enterotomies are preferred and multiple enterotomies should be avoided. A confirmatory radiological study is needed to demonstrate complete clearance of packets. A systematic protocol for the management of body packers results in minimal morbidity and no mortality.

Anticipating Forest and Range Land Development in Central Oregon (USA) for Landscape Analysis, with an Example Application Involving Mule Deer

NASA Astrophysics Data System (ADS)

Kline, Jeffrey D.; Moses, Alissa; Burcsu, Theresa

2010-05-01

Forest policymakers, public lands managers, and scientists in the Pacific Northwest (USA) seek ways to evaluate the landscape-level effects of policies and management through the multidisciplinary development and application of spatially explicit methods and models. The Interagency Mapping and Analysis Project (IMAP) is an ongoing effort to generate landscape-wide vegetation data and models to evaluate the integrated effects of disturbances and management activities on natural resource conditions in Oregon and Washington (USA). In this initial analysis, we characterized the spatial distribution of forest and range land development in a four-county pilot study region in central Oregon. The empirical model describes the spatial distribution of buildings and new building construction as a function of population growth, existing development, topography, land-use zoning, and other factors. We used the model to create geographic information system maps of likely future development based on human population projections to inform complementary landscape analyses underway involving vegetation, habitat, and wildfire interactions. In an example application, we use the model and resulting maps to show the potential impacts of future forest and range land development on mule deer ( Odocoileus hemionus) winter range. Results indicate significant development encroachment and habitat loss already in 2000 with development located along key migration routes and increasing through the projection period to 2040. The example application illustrates a simple way for policymakers and public lands managers to combine existing data and preliminary model outputs to begin to consider the potential effects of development on future landscape conditions.

Constraints on the tectonics of the Mule Mountains Thrust System, southeast California and southwest Arizona

NASA Astrophysics Data System (ADS)

Tosdal, Richard M.

1990-11-01

The Mule Mountains thrust system crops out discontinuously over a 100-km-strike length in the Blythe-Quartzsite region of southeast California and southwest Arizona. Along the thrust system, middle and upper crustal metamorphic and plutonic rocks of Proterozoic and Mesozoic age are thrust north-northeastward (015° to 035°) over a lower plate metamorphic terrane that formed part of the Proterozoic North American craton, its Paleozoic sedimentary rock cover, overlying Mesozoic volcanic and sedimentary rocks, and the intruding Jurassic and Cretaceous granitic rocks. Stratigraphic, petrologic, and Pb isotopic ties for Jurassic granitoids and for Jurassic(?) and Cretaceous sedimentary rocks across the various parts of the thrust system indicate that related crustal blocks are superposed and preclude it from having large displacements. The thick-skinned thrust system is structurally symmetrical along its length with a central domain of synmetamorphic thrust faults that are flanked by western and eastern domains where lower plate synclines underlie the thrusts. Deformation occurred under low greenschist facies metamorphic conditions in the upper crust. Movement along the thrust system was probably limited to no more than a few tens of kilometers and occurred between 79±2 Ma and 70±4 Ma. The superposition of related rocks and the geometry of the thrust system preclude it from being a major tectonic boundary of post-Middle Jurassic age, as has been previously proposed. Rather, the thrust system forms the southern boundary of the narrow zone of Cretaceous intracratonic deformation, and it is one of the last tectonic events in the zone prior to regional cooling.

Exotic pediculosis and hair-loss syndrome in deer (Odocoileus hemionus) populations in California.

PubMed

Roug, Annette; Swift, Pamela; Puschner, Birgit; Gerstenberg, Greg; Mertins, James W; Johnson, Christine Kreuder; Torres, Steve; Mortensen, Jack; Woods, Leslie

2016-07-01

Infestation with nonnative, "exotic" lice was first noted in Washington black-tailed deer (Odocoileus hemionus columbianus) in 1994 and has since then spread throughout the western United States. In California, infestation with the exotic louse Damalinia (Cervicola) sp. was first detected in black-tailed deer from northern California in 2004, and, in 2009, the exotic louse species Bovicola tibialis and Linognathus africanus were identified on mule deer (Odocoileus hemionus californicus) in central Sierra Nevada in association with a mortality event. Exotic lice have since been detected in various locations throughout the state. We describe the geographic distribution of these exotic lice within California, using data from 520 live-captured and 9 postmortem-sampled, free-ranging mule deer examined between 2009 and 2014. Data from live-captured deer were used to assess possible associations between louse infestation and host age, host sex, migratory behavior, season, and blood selenium and serum copper concentrations. Damalinia (Cervicola) sp. and B. tibialis lice were distinctively distributed geographically, with D. (Cervicola) sp. infesting herds in northern and central coastal California, B. tibialis occurring in the central coastal mountains and the Sierra Nevada, and L. africanus occurring only sporadically. Younger age classes and low selenium concentrations were significantly associated with exotic louse infestation, whereas no significant relationship was detected with serum copper levels. Our results show that exotic lice are widespread in California, and younger age classes with low blood selenium concentrations are more likely to be infested with lice than older deer. © 2016 The Author(s).