Science.gov

Sample records for multi-channel high time

  1. Multi-channel picosecond photon timing with microchannel plate detectors

    NASA Astrophysics Data System (ADS)

    Lapington, J. S.; Conneely, T.

    2011-08-01

    Microchannel plate-based detectors have the capability to photon-count at time resolutions which outperform solid-state devices such as the APD or SiPM, and have a geometry that lends itself to pixelated readouts. We describe a multi-channel, photon-counting microchannel plate detector optimised for photon timing in the picosecond regime. The detector was originally developed for application to time-resolved spectroscopy in the life sciences, however its performance characteristics make it suitable for applications where high time resolution and multi-channel photon-counting are required including Cherenkov light detection in nuclear physics, particle physics, and astroparticle astronomy.We describe the prototype detector, a sealed tube device comprising an optical photocathode proximity focussed to a small pore microchannel plate stack. Event charge is collected on a multi-channel readout comprising an 8×8 pixel array, manufactured on a multilayer ceramic, which provides vacuum integrity for the detector enclosure and a multi-way electrical feedthrough for the readout array. Each pixel addresses one channel of a NINO ASIC, a multi-channel preamplifier-discriminator device. The discriminator outputs are timed to 25 ps by the HPTDC time-to-digital converter ASIC, which uses a time-over-threshold technique for amplitude walk correction. We present performance measurements using a pulsed laser of the 64 channel prototype system comprising a 25 mm detector, NINO front-end, and a CAEN V1290A VME module utilising HPTDC. We discuss the next phase in the project—design and manufacture of a 40 mm detector with a 16×16 pixel2 readout coupled to custom NINO/HPTDC electronics constructed as a series of 64 channel modules, expandable to even larger channel densities.

  2. Highly time-resolved evaluation technique of instantaneous amplitude and phase difference using analytic signals for multi-channel diagnostics

    SciTech Connect

    Ohshima, S. Kobayashi, S.; Yamamoto, S.; Nagasaki, K.; Mizuuchi, T.; Kado, S.; Okada, H.; Minami, T.; Shi, N.; Konoshima, S.; Sano, F.; Lee, H. Y.; Zang, L.; Kenmochi, N.; Kasajima, K.; Ohtani, Y.; Nagae, Y.

    2014-11-15

    A fluctuation analysis technique using analytic signals is proposed. Analytic signals are suitable to characterize a single mode with time-dependent amplitude and frequency, such as an MHD mode observed in fusion plasmas since the technique can evaluate amplitude and frequency at a specific moment without limitations of temporal and frequency resolutions, which is problematic in Fourier-based analyses. Moreover, a concept of instantaneous phase difference is newly introduced, and error of the evaluated phase difference and its error reduction techniques using conditional/ensemble averaging are discussed. These techniques are applied to experimental data of the beam emission spectroscopic measurement in the Heliotron J device, which demonstrates that the technique can describe nonlinear evolution of MHD instabilities. This technique is widely applicable to other diagnostics having necessity to evaluate phase difference.

  3. A multi-channel high-? SQUID system and its application

    NASA Astrophysics Data System (ADS)

    Itozaki, Hideo; Tanaka, Saburou; Toyoda, Haruhisa; Hirano, Tetsuya; Haruta, Yasuhiro; Nomura, Masahiro; Saijou, Tetsuya; Kado, Hisashi

    1996-04-01

    A multi-channel high-temperature superconducting interference device (high-0953-2048/9/4A/011/img11 SQUID) system has been developed. Step edge junctions were employed for the SQUID. Magnetic field resolution was in the range 0953-2048/9/4A/011/img12 at 1 Hz, 0953-2048/9/4A/011/img13 at 10 Hz and 0953-2048/9/4A/011/img14 at 1 kHz. We have designed and developed 16-channel and 32-channel high-0953-2048/9/4A/011/img11 SQUID systems. We used them in a magnetically shielded room to measure magnetic signals of the human heart. We obtained clear multi-channel magnetocardiac signals, which showed clearly the R, S, and T wave peaks. A clear isofield contour map of magnetocardiac signals was also obtained. We also observed activities of the stomach using a tiny steel ball as a tracer. These data indicate that the use of the high-0953-2048/9/4A/011/img11 SQUID is feasible for these biomagnetic applications.

  4. High performance multi-channel MOSFET on InGaAs for RF amplifiers

    NASA Astrophysics Data System (ADS)

    Adhikari, Manoj Singh; Singh, Yashvir

    2017-02-01

    In this paper, we propose a multi-channel MOSFET (MC-MOSFET) on In0.53Ga0.47As for the first time by utilising trenches in the conventional planar MOSFET (CP-MOSFET) for RF amplifier applications. The proposed multi-channel MOSFET (MC-MOSFET) has two vertical-gates placed in trenches creating multiple channels in p-body for parallel conduction of drain current. High-k Al2O3 having thickness of 2 nm is used as gate dielectric in the proposed device. The TaN gate electrodes are placed in two different trenches in the p-type InGaAs layer where multiple n-channels are formed. Simultaneous conduction from multiple channels enhances the drain current (ID) and gives higher transconductance (gm) leading to improvement in overall frequency response. Two-dimensional (2D) numerical simulations of both MC-MOSFET and CP-MOSFET are performed by using ATLAS device simulator and their different performance parameters are compared. The proposed multi-channel structure provides 6.79 times higher ID, 5.57 times improvement in gm, 2.5 times increase in unity current gain (ft), 15.85% higher unilateral power gain (fmax) and suppress the short-channel effects (SCEs) as compared with the CP-MOSFET.

  5. Development of a Multi-Channel, High Frequency QRS Electrocardiograph

    NASA Technical Reports Server (NTRS)

    DePalma, Jude L.

    2003-01-01

    With the advent of the ISS era and the potential requirement for increased cardiovascular monitoring of crewmembers during extended EVAs, NASA flight surgeons would stand to benefit from an evolving technology that allows for a more rapid diagnosis of myocardial ischemia compared to standard electrocardiography. Similarly, during the astronaut selection process, NASA flight surgeons and other physicians would also stand to benefit from a completely noninvasive technology that, either at rest or during maximal exercise tests, is more sensitive than standard ECG in identifying the presence of ischemia. Perhaps most importantly, practicing cardiologists and emergency medicine physicians could greatly benefit from such a device as it could augment (or even replace) standard electrocardiography in settings where the rapid diagnosis of myocardial ischemia (or the lack thereof) is required for proper clinical decision-making. A multi-channel, high-frequency QRS electrocardiograph is currently under development in the Life Sciences Research Laboratories at JSC. Specifically the project consisted of writing software code, some of which contained specially-designed digital filters, which will be incorporated into an existing commercial software program that is already designed to collect, plot and analyze conventional 12-lead ECG signals on a desktop, portable or palm PC. The software will derive the high-frequency QRS signals, which will be analyzed (in numerous ways) and plotted alongside of the conventional ECG signals, giving the PC-viewing clinician advanced diagnostic information that has never been available previously in all 12 ECG leads simultaneously. After the hardware and software for the advanced digital ECG monitor have been fully integrated, plans are to use the monitor to begin clinical studies both on healthy subjects and on patients with known coronary artery disease in both the outpatient and hospital settings. The ultimate goal is to get the technology

  6. Laser time-of-flight measurement based on multi-channel time delay estimation

    NASA Astrophysics Data System (ADS)

    Li, Chao; Chen, Qian; Gu, Guohua; Man, Tian

    2013-03-01

    In this paper, a novel method based on multichannel time delay estimation with linear fitting correction for laser time-of-flight (TOF) measurement is described. The laser TOF measurement system is constructed with a laser source, a stop receiver channel, a reference receiver multichannel, an ADC sampling unit and a digital signal processing unit. Limited by the sampling rate, the precision of laser TOF measurement is restricted no more than the ADC sampling period in conventional methods. As this problem is considered, multi-channel correlation time delay estimation with linear fitting correction is devised. It is shown that the measuring precision is better than 2ns with multi-channel time delay estimation and not influenced by SNR. The experimental results demonstrate that the proposed method is effective and stable.

  7. Integrated multi-channel receiver for a pulsed time-of-flight laser radar

    NASA Astrophysics Data System (ADS)

    Jiang, Yan; Liu, Ruqing; Zhu, Jingguo

    2015-04-01

    An integrated multi-channel receiver for a pulsed time-of-flight (TOF) laser rangefinder has been designed in this paper. The receiver chip as an important component of the laser radar device has been implemented in a 0.18um CMOS process. It consists of sixteen channels and every channel includes preamplifier, amplifier stages, high-pass filter and a timing discriminator which contains a timing comparator and a noise comparator. Each signal paths is independent of other channels. Based on the simulations, the bandwidth and transimpedance of the amplifier channel are 652MHz, 99dBΩ. Under the simulation condition of TT corner and 27°C, the propagation delay of the discriminator is 2.15ns and the propagation delay dispersion is 223ps. The power consumption during continuous measurement is 810mW, and the operating temperature range of the device is -10~60°C.

  8. A portable multi-channel wireless NIRS device for muscle activity real-time monitoring.

    PubMed

    Yao, Pengfei; Guo, Weichao; Sheng, Xinjun; Zhang, Dingguo; Zhu, Xiangyang

    2014-01-01

    Near-infrared spectroscopy (NIRS) is a relative new technology in monitoring muscle oxygenation and hemo-dynamics. This paper presents a portable multi-channel wireless NIRS device for real-time monitoring of muscle activity. The NIRS sensor is designed miniaturized and modularized, to make multi-site monitoring convenient. Wireless communication is applied to data transmission avoiding of cumbersome wires and the whole system is highly integrated. Special care is taken to eliminate motion artifact when designing the NIRS sensor and attaching it to human skin. Besides, the system is designed with high sampling rate so as to monitor rapid oxygenation changes during muscle activities. Dark noise and long-term drift tests have been carried out, and the result indicates the device has a good performance of accuracy and stability. In vivo experiments including arterial occlusion and isometric voluntary forearm muscle contraction were performed, demonstrating the system has the ability to monitor muscle oxygenation parameters effectively even in exercise.

  9. Multi-channel holographic birfurcative neural network system for real-time adaptive EOS data analysis

    NASA Technical Reports Server (NTRS)

    Liu, Hua-Kuang; Diep, J.; Huang, K.

    1991-01-01

    Viewgraphs on multi-channel holographic bifurcative neural network system for real-time adaptive Earth Observing System (EOS) data analysis are presented. The objective is to research and develop an optical bifurcating neuromorphic pattern recognition system for making optical data array comparisons and to evaluate the use of the system for EOS data classification, reduction, analysis, and other applications.

  10. Multi-channel holographic birfurcative neural network system for real-time adaptive EOS data analysis

    NASA Technical Reports Server (NTRS)

    Liu, Hua-Kuang; Diep, J.; Huang, K.

    1991-01-01

    Viewgraphs on multi-channel holographic bifurcative neural network system for real-time adaptive Earth Observing System (EOS) data analysis are presented. The objective is to research and develop an optical bifurcating neuromorphic pattern recognition system for making optical data array comparisons and to evaluate the use of the system for EOS data classification, reduction, analysis, and other applications.

  11. Multi-channel data acquisition system with absolute time synchronization

    NASA Astrophysics Data System (ADS)

    Włodarczyk, Przemysław; Pustelny, Szymon; Budker, Dmitry; Lipiński, Marcin

    2014-11-01

    We present a low-cost, stand-alone global-time-synchronized data acquisition system. Our prototype allows recording up to four analog signals with a 16-bit resolution in variable ranges and a maximum sampling rate of 1000 S/s. The system simultaneously acquires readouts of external sensors e.g. magnetometer or thermometer. A complete data set, including a header containing timestamp, is stored on a Secure Digital (SD) card or transmitted to a computer using Universal Serial Bus (USB). The estimated time accuracy of the data acquisition is better than ±200 ns. The device is intended for use in a global network of optical magnetometers (the Global Network of Optical Magnetometers for Exotic physics - GNOME), which aims to search for signals heralding physics beyond the Standard Model, that can be generated by ordinary spin coupling to exotic particles or anomalous spin interactions.

  12. Continuous flow real-time PCR device using multi-channel fluorescence excitation and detection.

    PubMed

    Hatch, Andrew C; Ray, Tathagata; Lintecum, Kelly; Youngbull, Cody

    2014-02-07

    High throughput automation is greatly enhanced using techniques that employ conveyor belt strategies with un-interrupted streams of flow. We have developed a 'conveyor belt' analog for high throughput real-time quantitative Polymerase Chain Reaction (qPCR) using droplet emulsion technology. We developed a low power, portable device that employs LED and fiber optic fluorescence excitation in conjunction with a continuous flow thermal cycler to achieve multi-channel fluorescence detection for real-time fluorescence measurements. Continuously streaming fluid plugs or droplets pass through tubing wrapped around a two-temperature zone thermal block with each wrap of tubing fluorescently coupled to a 64-channel multi-anode PMT. This work demonstrates real-time qPCR of 0.1-10 μL droplets or fluid plugs over a range of 7 orders of magnitude concentration from 1 × 10(1) to 1 × 10(7). The real-time qPCR analysis allows dynamic range quantification as high as 1 × 10(7) copies per 10 μL reaction, with PCR efficiencies within the range of 90-110% based on serial dilution assays and a limit of detection of 10 copies per rxn. The combined functionality of continuous flow, low power thermal cycling, high throughput sample processing, and real-time qPCR improves the rates at which biological or environmental samples can be continuously sampled and analyzed.

  13. Device for modular input high-speed multi-channel digitizing of electrical data

    DOEpatents

    VanDeusen, A.L.; Crist, C.E.

    1995-09-26

    A multi-channel high-speed digitizer module converts a plurality of analog signals to digital signals (digitizing) and stores the signals in a memory device. The analog input channels are digitized simultaneously at high speed with a relatively large number of on-board memory data points per channel. The module provides an automated calibration based upon a single voltage reference source. Low signal noise at such a high density and sample rate is accomplished by ensuring the A/D converters are clocked at the same point in the noise cycle each time so that synchronous noise sampling occurs. This sampling process, in conjunction with an automated calibration, yields signal noise levels well below the noise level present on the analog reference voltages. 1 fig.

  14. Device for modular input high-speed multi-channel digitizing of electrical data

    DOEpatents

    VanDeusen, Alan L.; Crist, Charles E.

    1995-09-26

    A multi-channel high-speed digitizer module converts a plurality of analog signals to digital signals (digitizing) and stores the signals in a memory device. The analog input channels are digitized simultaneously at high speed with a relatively large number of on-board memory data points per channel. The module provides an automated calibration based upon a single voltage reference source. Low signal noise at such a high density and sample rate is accomplished by ensuring the A/D converters are clocked at the same point in the noise cycle each time so that synchronous noise sampling occurs. This sampling process, in conjunction with an automated calibration, yields signal noise levels well below the noise level present on the analog reference voltages.

  15. Self-adaptive method for high frequency multi-channel analysis of surface wave method

    USDA-ARS?s Scientific Manuscript database

    When the high frequency multi-channel analysis of surface waves (MASW) method is conducted to explore soil properties in the vadose zone, existing rules for selecting the near offset and spread lengths cannot satisfy the requirements of planar dominant Rayleigh waves for all frequencies of interest ...

  16. The dynamic time-over-threshold method for multi-channel APD based gamma-ray detectors

    NASA Astrophysics Data System (ADS)

    Orita, T.; Shimazoe, K.; Takahashi, H.

    2015-03-01

    t- Recent advances in manufacturing technology have enabled the use of multi-channel pixelated detectors in gamma-ray imaging applications. When obtaining gamma-ray measurements, it is important to obtain pulse height information in order to avoid unnecessary events such as scattering. However, as the number of channels increases, more electronics are needed to process each channel's signal, and the corresponding increases in circuit size and power consumption can result in practical problems. The time-over-threshold (ToT) method, which has recently become popular in the medical field, is a signal processing technique that can effectively avoid such problems. However, ToT suffers from poor linearity and its dynamic range is limited. We therefore propose a new ToT technique called the dynamic time-over-threshold (dToT) method [4]. A new signal processing system using dToT and CR-RC shaping demonstrated much better linearity than that of a conventional ToT. Using a test circuit with a new Gd3Al2Ga3O12 (GAGG) scintillator and an avalanche photodiode, the pulse height spectra of 137Cs and 22Na sources were measured with high linearity. Based on these results, we designed a new application-specific integrated circuit (ASIC) for this multi-channel dToT system, measured the spectra of a 22Na source, and investigated the linearity of the system.

  17. Miniature real time PCR on chip with multi-channel fiber optical fluorescence detection module.

    PubMed

    Xiang, Q; Xu, B; Li, D

    2007-08-01

    This paper presents the design and implementation of a miniature real time PCR system consisting of a disposable reactor chip, a miniature thermal cycler, and a multi-channel fiber optical fluorescence excitation/detection module. The disposable PCR chip is fabricated by using soft photolithography by PDMS (Polydimethylsiloxane) and glass. The miniature thermal cycler has a thin film heater for heating and a fan for rapid cooling. The fiber optical detection module consists of laser, filter cube, photo-detector and 1x4 fiber optical switch. It is capable of four-well real time PCR analysis. Real-time PCR detection of E. coli stx1 has been demonstrated successfully with this system.

  18. High Speed, Multi-Channel, Thermal Instrument Development in Support of HyspIRI-TIR

    NASA Technical Reports Server (NTRS)

    Johnson, William R.; Hook, Simon J.; Foote, Marc; Eng, Bjorn T.; Jau, Bruno

    2011-01-01

    The Jet Propulsion Laboratory is currently developing an end-to-end instrument which will provide a proof of concept prototype vehicle for a high data rate, multi-channel, thermal instrument in support of the Hyperspectral Infrared Imager (HyspIRI)-Thermal Infrared (TIR) space mission. HyspIRI mission was recommended by the National Research Council Decadal Survey (DS). The HyspIRI mission includes a visible shortwave infrared (SWIR) pushboom spectrometer and a multispectral whiskbroom thermal infrared (TIR) imager. The prototype testbed instrument addressed in this effort will only support the TIR. Data from the HyspIRI mission will be used to address key science questions related to the Solid Earth and Carbon Cycle and Ecosystems focus areas of the NASA Science Mission Directorate. Current designs for the HyspIRI-TIR space borne imager utilize eight spectral bands delineated with filters. The system will have 60m ground resolution, 200mK NEDT, 0.5C absolute temperature resolution with a 5-day repeat from LEO orbit. The prototype instrument will use mercury cadmium telluride (MCT) technology at the focal plane array in time delay integration mode. A custom read out integrated circuit (ROIC) will provide the high speed readout hence high data rates needed for the 5 day repeat. The current HyspIRI requirements dictate a ground knowledge measurement of 30m, so the prototype instrument will tackle this problem with a newly developed interferometeric metrology system. This will provide an absolute measurement of the scanning mirror to an order of magnitude better than conventional optical encoders. This will minimize the reliance on ground control points hence minimizing postprocessing (e.g. geo-rectification computations).

  19. High speed, multi-channel, thermal instrument development in support of HyspIRI-TIR

    NASA Astrophysics Data System (ADS)

    Johnson, William R.; Hook, Simon J.; Foote, Marc; Eng, Bjorn T.; Jau, Bruno

    2011-10-01

    The Jet Propulsion Laboratory is currently developing an end-to-end instrument which will provide a proof of concept prototype vehicle for a high data rate, multi-channel, thermal instrument in support of the Hyperspectral Infrared Imager (HyspIRI)-Thermal Infrared (TIR) space mission. HyspIRI mission was recommended by the National Research Council Decadal Survey (DS). The HyspIRI mission includes a visible shortwave infrared (SWIR) pushboom spectrometer and a multispectral whiskbroom thermal infrared (TIR) imager. The prototype testbed instrument addressed in this effort will only support the TIR. Data from the HyspIRI mission will be used to address key science questions related to the Solid Earth and Carbon Cycle and Ecosystems focus areas of the NASA Science Mission Directorate. Current designs for the HyspIRI-TIR space borne imager utilize eight spectral bands delineated with filters. The system will have 60m ground resolution, 200mK NEDT, 0.5C absolute temperature resolution with a 5-day repeat from LEO orbit. The prototype instrument will use mercury cadmium telluride (MCT) technology at the focal plane array in time delay integration mode. A custom read out integrated circuit (ROIC) will provide the high speed readout hence high data rates needed for the 5 day repeat. The current HyspIRI requirements dictate a ground knowledge measurement of 30m, so the prototype instrument will tackle this problem with a newly developed interferometeric metrology system. This will provide an absolute measurement of the scanning mirror to an order of magnitude better than conventional optical encoders. This will minimize the reliance on ground control points hence minimizing postprocessing (e.g. geo-rectification computations).

  20. High Speed, Multi-Channel, Thermal Instrument Development in Support of HyspIRI-TIR

    NASA Technical Reports Server (NTRS)

    Johnson, William R.; Hook, Simon J.; Foote, Marc; Eng, Bjorn T.; Jau, Bruno

    2011-01-01

    The Jet Propulsion Laboratory is currently developing an end-to-end instrument which will provide a proof of concept prototype vehicle for a high data rate, multi-channel, thermal instrument in support of the Hyperspectral Infrared Imager (HyspIRI)-Thermal Infrared (TIR) space mission. HyspIRI mission was recommended by the National Research Council Decadal Survey (DS). The HyspIRI mission includes a visible shortwave infrared (SWIR) pushboom spectrometer and a multispectral whiskbroom thermal infrared (TIR) imager. The prototype testbed instrument addressed in this effort will only support the TIR. Data from the HyspIRI mission will be used to address key science questions related to the Solid Earth and Carbon Cycle and Ecosystems focus areas of the NASA Science Mission Directorate. Current designs for the HyspIRI-TIR space borne imager utilize eight spectral bands delineated with filters. The system will have 60m ground resolution, 200mK NEDT, 0.5C absolute temperature resolution with a 5-day repeat from LEO orbit. The prototype instrument will use mercury cadmium telluride (MCT) technology at the focal plane array in time delay integration mode. A custom read out integrated circuit (ROIC) will provide the high speed readout hence high data rates needed for the 5 day repeat. The current HyspIRI requirements dictate a ground knowledge measurement of 30m, so the prototype instrument will tackle this problem with a newly developed interferometeric metrology system. This will provide an absolute measurement of the scanning mirror to an order of magnitude better than conventional optical encoders. This will minimize the reliance on ground control points hence minimizing postprocessing (e.g. geo-rectification computations).

  1. High-throughput hyperpolarized (13)C metabolic investigations using a multi-channel acquisition system.

    PubMed

    Lee, Jaehyuk; Ramirez, Marc S; Walker, Christopher M; Chen, Yunyun; Yi, Stacey; Sandulache, Vlad C; Lai, Stephen Y; Bankson, James A

    2015-11-01

    Magnetic resonance imaging and spectroscopy of hyperpolarized (HP) compounds such as [1-(13)C]-pyruvate have shown tremendous potential for offering new insight into disease and response to therapy. New applications of this technology in clinical research and care will require extensive validation in cells and animal models, a process that may be limited by the high cost and modest throughput associated with dynamic nuclear polarization. Relatively wide spectral separation between [1-(13)C]-pyruvate and its chemical endpoints in vivo are conducive to simultaneous multi-sample measurements, even in the presence of a suboptimal global shim. Multi-channel acquisitions could conserve costs and accelerate experiments by allowing acquisition from multiple independent samples following a single dissolution. Unfortunately, many existing preclinical MRI systems are equipped with only a single channel for broadband acquisitions. In this work, we examine the feasibility of this concept using a broadband multi-channel digital receiver extension and detector arrays that allow concurrent measurement of dynamic spectroscopic data from ex vivo enzyme phantoms, in vitro anaplastic thyroid carcinoma cells, and in vivo in tumor-bearing mice. Throughput and the cost of consumables were improved by up to a factor of four. These preliminary results demonstrate the potential for efficient multi-sample studies employing hyperpolarized agents. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. High-throughput hyperpolarized 13C metabolic investigations using a multi-channel acquisition system

    NASA Astrophysics Data System (ADS)

    Lee, Jaehyuk; Ramirez, Marc S.; Walker, Christopher M.; Chen, Yunyun; Yi, Stacey; Sandulache, Vlad C.; Lai, Stephen Y.; Bankson, James A.

    2015-11-01

    Magnetic resonance imaging and spectroscopy of hyperpolarized (HP) compounds such as [1-13C]-pyruvate have shown tremendous potential for offering new insight into disease and response to therapy. New applications of this technology in clinical research and care will require extensive validation in cells and animal models, a process that may be limited by the high cost and modest throughput associated with dynamic nuclear polarization. Relatively wide spectral separation between [1-13C]-pyruvate and its chemical endpoints in vivo are conducive to simultaneous multi-sample measurements, even in the presence of a suboptimal global shim. Multi-channel acquisitions could conserve costs and accelerate experiments by allowing acquisition from multiple independent samples following a single dissolution. Unfortunately, many existing preclinical MRI systems are equipped with only a single channel for broadband acquisitions. In this work, we examine the feasibility of this concept using a broadband multi-channel digital receiver extension and detector arrays that allow concurrent measurement of dynamic spectroscopic data from ex vivo enzyme phantoms, in vitro anaplastic thyroid carcinoma cells, and in vivo in tumor-bearing mice. Throughput and the cost of consumables were improved by up to a factor of four. These preliminary results demonstrate the potential for efficient multi-sample studies employing hyperpolarized agents.

  3. Image reconstruction of multi-channel photoacoustic and laser-ultrasound data using reverse time migration

    NASA Astrophysics Data System (ADS)

    Johnson, Jami L.; Shragge, Jeffrey; van Wijk, Kasper

    2015-03-01

    We propose a new reconstruction algorithm for photoacoustic and laser-ultrasound imaging based on reverse time migration (RTM), a time reversal imaging algorithm originally developed for exploration seismology. RTM inherently handles strong velocity heterogeneity and complex propagation paths. A successful RTM analysis with appropriate handling of boundary conditions results in enhanced signal-to-noise, accurately located structures, and minimal artifacts. A laser-ultrasound experiment begins with a source wave field generated at the surface that propagates through the sample. Acoustic scatterers in the propagation path give rise to a scattered wave field, which travels to the surface and is recorded by acoustic detectors. To reconstruct the laser-ultrasound image, a synthetic source function is forward propagated and cross-correlated with the time-reversed and back-propagated recorded (scattered) wave field to image the scatterers at the correct location. Conversely, photoacoustic waves are generated by chromophores within the sample and propagate "one-way" to the detection surface. We utilize the velocity model validated by the laser-ultrasound reconstruction to accurately reconstruct the photoacoustic image with RTM. This approach is first validated with simulations, where inclusions behave both as a photoacoustic source and an acoustic scatterer. Subsequently, we demonstrate the capabilities of RTM with tissue phantom experiments using an all-optical, multi-channel acquisition geometry.

  4. Note: Multi channel Doppler tuned spectrometer to study highly charged ions.

    PubMed

    Karn, Ranjeet K; Mishra, C N; Ahmad, Nissar; Saini, S K; Safvan, C P; Nandi, T

    2014-06-01

    We describe the design and implementation of a multi channel Doppler tuned spectrometer setup to study physics of highly charged ions at high resolution in a direct way. A unique Soller slit assembly coupled with a long one dimensional position sensitive proportional counter enables us to get distinct x-ray peaks at different angles, which allows us to cover large number of angle in one shot. By using this setup, 1s2s (3)S1 - 1s(2) (1)S0 M1 transition in He-like Fe has been resolved from its satellite line 1s2s2p ⁴P(5/2)⁰ - 1s(2)2s (2)S(1/2) M2 transition in Li-like Fe and measured the lifetime of their respective upper levels with high precision.

  5. Time-varying bispectral analysis of visually evoked multi-channel EEG

    NASA Astrophysics Data System (ADS)

    Chandran, Vinod

    2012-12-01

    Theoretical foundations of higher order spectral analysis are revisited to examine the use of time-varying bicoherence on non-stationary signals using a classical short-time Fourier approach. A methodology is developed to apply this to evoked EEG responses where a stimulus-locked time reference is available. Short-time windowed ensembles of the response at the same offset from the reference are considered as ergodic cyclostationary processes within a non-stationary random process. Bicoherence can be estimated reliably with known levels at which it is significantly different from zero and can be tracked as a function of offset from the stimulus. When this methodology is applied to multi-channel EEG, it is possible to obtain information about phase synchronization at different regions of the brain as the neural response develops. The methodology is applied to analyze evoked EEG response to flash visual stimulii to the left and right eye separately. The EEG electrode array is segmented based on bicoherence evolution with time using the mean absolute difference as a measure of dissimilarity. Segment maps confirm the importance of the occipital region in visual processing and demonstrate a link between the frontal and occipital regions during the response. Maps are constructed using bicoherence at bifrequencies that include the alpha band frequency of 8Hz as well as 4 and 20Hz. Differences are observed between responses from the left eye and the right eye, and also between subjects. The methodology shows potential as a neurological functional imaging technique that can be further developed for diagnosis and monitoring using scalp EEG which is less invasive and less expensive than magnetic resonance imaging.

  6. A real-time multi-channel monitoring system for stem cell culture process.

    PubMed

    Xicai Yue; Drakakis, E M; Lim, M; Radomska, A; Hua Ye; Mantalaris, A; Panoskaltsis, N; Cass, A

    2008-06-01

    A novel, up to 128 channels, multi-parametric physiological measurement system suitable for monitoring hematopoietic stem cell culture processes and cell cultures in general is presented in this paper. The system aims to measure in real-time the most important physical and chemical culture parameters of hematopoietic stem cells, including physicochemical parameters, nutrients, and metabolites, in a long-term culture process. The overarching scope of this research effort is to control and optimize the whole bioprocess by means of the acquisition of real-time quantitative physiological information from the culture. The system is designed in a modular manner. Each hardware module can operate as an independent gain programmable, level shift adjustable, 16 channel data acquisition system specific to a sensor type. Up to eight such data acquisition modules can be combined and connected to the host PC to realize the whole system hardware. The control of data acquisition and the subsequent management of data is performed by the system's software which is coded in LabVIEW. Preliminary experimental results presented here show that the system not only has the ability to interface to various types of sensors allowing the monitoring of different types of culture parameters. Moreover, it can capture dynamic variations of culture parameters by means of real-time multi-channel measurements thus providing additional information on both temporal and spatial profiles of these parameters within a bioreactor. The system is by no means constrained in the hematopoietic stem cell culture field only. It is suitable for cell growth monitoring applications in general.

  7. Compensation of multi-channel mismatches in high-speed high-resolution photonic analog-to-digital converter.

    PubMed

    Yang, Guang; Zou, Weiwen; Yu, Lei; Wu, Kan; Chen, Jianping

    2016-10-17

    We demonstrate a method to compensate multi-channel mismatches that intrinsically exist in a photonic analog-to-digital converter (ADC) system. This system, nominated time-wavelength interleaved photonic ADC (TWI-PADC), is time-interleaved via wavelength demultiplexing/multiplexing before photonic sampling, wavelength demultiplexing channelization, and electronic quantization. Mismatches among multiple channels are estimated in frequency domain and hardware adjustment are used to approach the device-limited accuracy. A multi-channel mismatch compensation algorithm, inspired from the time-interleaved electronic ADC, is developed to effectively improve the performance of TWI-PADC. In the experiment, we configure out a 4-channel TWI-PADC system with 40 GS/s sampling rate based on a 10-GHz actively mode-locked fiber laser. After multi-channel mismatch compensation, the effective number of bit (ENOB) of the 40-GS/s TWI-PADC system is enhanced from ~6 bits to >8.5 bits when the RF frequency is within 0.1-3.1 GHz and from ~6 bits to >7.5 bits within 3.1-12.1 GHz. The enhanced performance of the TWI-PADC system approaches the limitation determined by the timing jitter and noise.

  8. Modelling Temporal Stability of EPI Time Series Using Magnitude Images Acquired with Multi-Channel Receiver Coils

    PubMed Central

    Hutton, Chloe; Balteau, Evelyne; Lutti, Antoine; Josephs, Oliver; Weiskopf, Nikolaus

    2012-01-01

    In 2001, Krueger and Glover introduced a model describing the temporal SNR (tSNR) of an EPI time series as a function of image SNR (SNR0). This model has been used to study physiological noise in fMRI, to optimize fMRI acquisition parameters, and to estimate maximum attainable tSNR for a given set of MR image acquisition and processing parameters. In its current form, this noise model requires the accurate estimation of image SNR. For multi-channel receiver coils, this is not straightforward because it requires export and reconstruction of large amounts of k-space raw data and detailed, custom-made image reconstruction methods. Here we present a simple extension to the model that allows characterization of the temporal noise properties of EPI time series acquired with multi-channel receiver coils, and reconstructed with standard root-sum-of-squares combination, without the need for raw data or custom-made image reconstruction. The proposed extended model includes an additional parameter κ which reflects the impact of noise correlations between receiver channels on the data and scales an apparent image SNR (SNR′0) measured directly from root-sum-of-squares reconstructed magnitude images so that κ = SNR′0/SNR0 (under the condition of SNR0>50 and number of channels ≤32). Using Monte Carlo simulations we show that the extended model parameters can be estimated with high accuracy. The estimation of the parameter κ was validated using an independent measure of the actual SNR0 for non-accelerated phantom data acquired at 3T with a 32-channel receiver coil. We also demonstrate that compared to the original model the extended model results in an improved fit to human task-free non-accelerated fMRI data acquired at 7T with a 24-channel receiver coil. In particular, the extended model improves the prediction of low to medium tSNR values and so can play an important role in the optimization of high-resolution fMRI experiments at lower SNR levels. PMID:23284874

  9. A sophisticated, multi-channel data acquisition and processing system for high frequency noise research

    NASA Technical Reports Server (NTRS)

    Hall, David G.; Bridges, James

    1992-01-01

    A sophisticated, multi-channel computerized data acquisition and processing system was developed at the NASA LeRC for use in noise experiments. This technology, which is available for transfer to industry, provides a convenient, cost-effective alternative to analog tape recording for high frequency acoustic measurements. This system provides 32-channel acquisition of microphone signals with an analysis bandwidth up to 100 kHz per channel. Cost was minimized through the use of off-the-shelf components. Requirements to allow for future expansion were met by choosing equipment which adheres to established industry standards for hardware and software. Data processing capabilities include narrow band and 1/3 octave spectral analysis, compensation for microphone frequency response/directivity, and correction of acoustic data to standard day conditions. The system was used successfully in a major wind tunnel test program at NASA LeRC to acquire and analyze jet noise data in support of the High Speed Civil Transport (HSCT) program.

  10. Silicon Photomultiplier-Based Multi-Channel Gamma Ray Detector Using the Dynamic Time-Over-Threshold Method

    NASA Astrophysics Data System (ADS)

    Nakamura, Y.; Shimazoe, K.; Takahashi, H.

    2016-02-01

    Silicon photomultipliers (SiPMs), which are a relatively new type of photon detector, have received more attention in the fields of nuclear medicine and high-energy physics because of their compactness and high gain up to 106. In this work, a SiPM-based multi-channel gamma ray detector with individual read out based on the dynamic time-over-threshold (dToT) method is implemented and demonstrated as an elemental material for large-area gamma ray imager applications. The detector consists of 64 channels of KETEK SiPM PM6660 (6 × 6 mm2 containing 10,000 micro-cells of 60 × 60 μm2) coupled to an 8 × 8 array of high-energy resolution Gd3(Al,Ga)5O12(Ce) (HR-GAGG) crystals (10 × 10 × 10 mm3) segmented by a 1 mm thick BaSO4 reflector. To produce a digital pulse containing linear energy information, the dToT-based read-out circuit consists of a CR-RC shaping amplifier (2.2 μs) and comparator with a feedback component. By modelling the pulse of the SiPM, the light output, and the CR-RC shaping amplifier, the integral-non-linearity (INL) was numerically calculated in terms of the delay time and the time constant of dynamic threshold movement. The experimental results of the averaged INL and energy resolution were 5.8±1.6% and the full-width-at-half-maximum (FWHM) of 7.4±0.9% at 662 keV, respectively. The 64-channel single-mode detector module was successfully implemented, demonstrating potential for its use as an elemental material for large-area gamma ray imaging applications.

  11. Multi-channel medical device for time domain functional near infrared spectroscopy based on wavelength space multiplexing

    PubMed Central

    Re, Rebecca; Contini, Davide; Turola, Massimo; Spinelli, Lorenzo; Zucchelli, Lucia; Caffini, Matteo; Cubeddu, Rinaldo; Torricelli, Alessandro

    2013-01-01

    We have designed a compact dual wavelength (687 nm, 826 nm) multi-channel (16 sources, 8 detectors) medical device for muscle and brain imaging based on time domain functional near infrared spectroscopy. The system employs the wavelength space multiplexing approach to reduce wavelength cross-talk and increase signal-to-noise ratio. System performances have been tested on homogeneous and heterogeneous tissue phantoms following specifically designed protocols for photon migration instruments. Preliminary in vivo measurements have been performed to validate the instrument capability to monitor hemodynamic parameters changes in the arm muscle during arterial occlusion and in the adult head during a motor task experiment. PMID:24156079

  12. Multi-channel high-resolution terahertz spectrometer for analytical studies

    NASA Astrophysics Data System (ADS)

    Vaks, V.; Domracheva, E.; Pripolzin, S.; Chernyaeva, M.; Yablokov, A.

    2016-12-01

    A method of multi-channel THz spectroscopy and a sample device that embodies the method were developed and described by the authors. The device has two independent THz radiation sources and a single receiving module. The novel method allows detecting preliminary and short-living chemical compounds and therefore to studychemical reaction dynamics. This has been shown by a series of test experiments. The method can be applied to researches in Physics, Chemistry, Astronomy, Medicine, and Biology.

  13. Sub-nanosecond multi-channel time-to-digital converter for the 2-D position-sensitive neutron detectors at TriCS and AMOR

    NASA Astrophysics Data System (ADS)

    Buehler, Ch.; Greuter, U.; Frey, G.; Zaharko, O.; Koennecke, M.; Schefer, J.; Rasmussen, P.; Schaniel, D.; Clemens, D.; Gabriel, A.; Felsche, J.; Schlumpf, N.

    We have developed an ultra-fast multi-channel time-to-digital converter (mC-TDC). The mC-TDC electronics is used to read out the delay-line-based 2-D detectors of the neutron diffractometer and reflectometer TriCS and AMOR, respectively. The high time resolution of the mC-TDC ( 145 ps) allows the conversion of the position-sensitive detector signals into accurate 2-D scattering coordinates ( 2×2 mm2). The mC-TDC also generates low-jitter time-of-flight signals and incorporates an efficient two-stage pileup-rejection mechanism. Neutron rates exceeding 100000cps can be processed.

  14. RF/microwave system high-fidelity modeling and simulation: application to airborne multi-channel receiver system for angle of arrival estimation

    NASA Astrophysics Data System (ADS)

    Wu, Chen; Rajan, Sreeraman; Young, Anne; O'Regan, Christina

    2014-06-01

    In this paper, a high-fidelity RF modeling and simulation framework is demonstrated to model an airborne multi-channel receiver system that is used to estimate the angle of arrival (AoA) of received signals from a stationary emitter. The framework is based on System Tool Kit (STK®), Matlab and SystemVue®. The SystemVue-based multi-channel receiver estimates the AoA of incoming signals using adjacent channel amplitude and phase comparisons, and it estimates the Doppler frequency shift of the aircraft by processing the transmitted and received signals. The estimated AoA and Doppler frequency are compared with the ground-truth data provided by STK to validate the efficacy of the modeling process. Unlike other current RF electronic warfare simulation frameworks, the received signal described herein is formed using the received power, the propagation delay and the transmitted waveform, and does not require information such as Doppler frequency shift or radial velocity of the moving platform from the scenario; hence, the simulation is more computationally efficient. In addition, to further reduce the overall modeling and simulation time, since the high-fidelity model computation is costly, the high-fidelity electronic system model is evoked only when the received power is higher than a predetermined threshold.

  15. A multi-channel device for high-density target-selective stimulation and long-term monitoring of cells and subcellular features in C. elegans.

    PubMed

    Lee, Hyewon; Kim, Shin Ae; Coakley, Sean; Mugno, Paula; Hammarlund, Marc; Hilliard, Massimo A; Lu, Hang

    2014-12-07

    Selective cell ablation can be used to identify neuronal functions in multicellular model organisms such as Caenorhabditis elegans. The optogenetic tool KillerRed facilitates selective ablation by enabling light-activated damage of cell or subcellular components in a temporally and spatially precise manner. However, the use of KillerRed requires stimulating (5 min-1 h), culturing (~24 h) and imaging (often repeatedly) a large number of individual animals. Current manual manipulation methods are limited by their time-consuming, labor-intensive nature, and their usage of anesthetics. To facilitate large-scale selective ablation, culturing, and repetitive imaging, we developed a densely-packed multi-channel device and used it to perform high-throughput neuronal ablation on KillerRed-expressing animals. The ability to load worms in identical locations with high loading efficiency allows us to ablate selected neurons in multiple worms simultaneously. Our device also enables continuous observation of animals for 24 h following KillerRed activation, and allows the animals to be recovered for behavioural assays. We expect this multi-channel device to facilitate a broad range of long-term imaging and selective illumination experiments in neuroscience.

  16. Multi-channel digital correlator and hardware simulator for fluorescence correlation spectroscopy, dynamic light scattering and multichannel photon time stamping

    NASA Astrophysics Data System (ADS)

    Lescano, Isaac; Davis, Lloyd

    2007-11-01

    In fluorescence correlation spectroscopy and dynamic light scattering, digital correlators acquire the autocorrelation function of detected photons to measure diffusional dynamics of biomolecules and small particles. Multi-channel data from different wavelengths or scattering angles provides increased information for resolving multiple species. Similarly, in single-molecule spectroscopy and in experiments on photon entanglement, there is a need to acquire time stamps of photons from multiple detectors. To enable such advances, we have developed a cost-effective 16-channel correlator, and also a hardware simulator for a 16-channel photon detector for testing digital correlators, each based on a National Instruments R-series reconfigurable digital i/o card. The correlator scans 16 digital inputs each 6.25 ns for photon detector pulses and sends the photon time stamp and channel data to the host PC via a FIFO and 3 DMA channels, allowing >10^7 counts/s among the 16 channels. The PC calculates all autocorrelation and cross-correlations for logarithmically spaced delays in a real-time algorithm. The hardware simulator works in reverse: Simulated time stamp and channel data are sent by DMA to the card, which generates TTL pulses for the 16 digital outputs as though they came from 16 real photon detectors.

  17. Search for High Rotation Measures in Extragalactic Radio Sources I. Multi-Channel Observations at 10 GHz

    NASA Astrophysics Data System (ADS)

    Inoue, M.; Tabara, H.; Kato, T.; Aizu, K.

    1995-12-01

    Multi-channel polarimetry has been performed to detect high rotation measure (RM) at 3 cm using the Nobeyama 45-m telescope. The high RM candidates of 96 radio sources were selected to be observed, and RMs of 35 sources were derived from the observations. Since the four channels are set contiguously from 2.84 cm to 3.31 cm, |RM| can be derived uniquely up to 15000 rad m(-2) by this polarimeter. We found that there exist sources with RM of several thousands rad m(-2) . In fact, 5 sources have |RM| > 1000 rad m(-2) . On the other hand, all sources observed are well within this system limits, and therefore we suggest the observed upper limit of |RM| is around 5000 rad m(-2) for extragalactic radio sources, even taken into account the redshift of sources.

  18. Taipei's use of a multi-channel mass risk communication program to rapidly reverse an epidemic of highly communicable disease.

    PubMed

    Yen, Muh-Yong; Wu, Tsung-Shu Joseph; Chiu, Allen Wen-Hsiang; Wong, Wing-Wai; Wang, Po-En; Chan, Ta-Chien; King, Chwan-Chuen

    2009-11-23

    In September 2007, an outbreak of acute hemorrhagic conjunctivitis (AHC) occurred in Keelung City and spread to Taipei City. In response to the epidemic, a new crisis management program was implemented and tested in Taipei. Having noticed that transmission surged on weekends during the Keelung epidemic, Taipei City launched a multi-channel mass risk communications program that included short message service (SMS) messages sent directly to approximately 2.2 million Taipei residents on Friday, October 12th, 2007. The public was told to keep symptomatic students from schools and was provided guidelines for preventing the spread of the disease at home. Epidemiological characteristics of Taipei's outbreak were analyzed from 461 sampled AHC cases. Median time from exposure to onset of the disease was 1 day. This was significantly shorter for cases occurring in family clusters than in class clusters (mean+/-SD: 2.6+/-3.2 vs. 4.39+/-4.82 days, p = 0.03), as well as for cases occurring in larger family clusters as opposed to smaller ones (1.2+/-1.7 days vs. 3.9+/-4.0 days, p<0.01). Taipei's program had a significant impact on patient compliance. Home confinement of symptomatic children increased from 10% to 60% (p<0.05) and helped curb the spread of AHC. Taipei experienced a rapid decrease in AHC cases between the Friday of the SMS announcement and the following Monday, October 15, (0.70% vs. 0.36%). By October 26, AHC cases reduced to 0.01%. The success of this risk communication program in Taipei (as compared to Keelung) is further reflected through rapid improvements in three epidemic indicators: (1) significantly lower crude attack rates (1.95% vs. 14.92%, p<0.001), (2) a short epidemic period of AHC (13 vs. 34 days), and (3) a quick drop in risk level (1 approximately 2 weeks) in Taipei districts that border Keelung (the original domestic epicenter). The timely launch of this systematic, communication-based intervention proved effective at preventing a dangerous spike

  19. Taipei's Use of a Multi-Channel Mass Risk Communication Program to Rapidly Reverse an Epidemic of Highly Communicable Disease

    PubMed Central

    Yen, Muh-Yong; Wu, Tsung-Shu Joseph; Chiu, Allen Wen-Hsiang; Wong, Wing-Wai; Wang, Po-En; Chan, Ta-Chien; King, Chwan-Chuen

    2009-01-01

    Background In September 2007, an outbreak of acute hemorrhagic conjunctivitis (AHC) occurred in Keelung City and spread to Taipei City. In response to the epidemic, a new crisis management program was implemented and tested in Taipei. Methodology and Principal Findings Having noticed that transmission surged on weekends during the Keelung epidemic, Taipei City launched a multi-channel mass risk communications program that included short message service (SMS) messages sent directly to approximately 2.2 million Taipei residents on Friday, October 12th, 2007. The public was told to keep symptomatic students from schools and was provided guidelines for preventing the spread of the disease at home. Epidemiological characteristics of Taipei's outbreak were analyzed from 461 sampled AHC cases. Median time from exposure to onset of the disease was 1 day. This was significantly shorter for cases occurring in family clusters than in class clusters (mean±SD: 2.6±3.2 vs. 4.39±4.82 days, p = 0.03), as well as for cases occurring in larger family clusters as opposed to smaller ones (1.2±1.7 days vs. 3.9±4.0 days, p<0.01). Taipei's program had a significant impact on patient compliance. Home confinement of symptomatic children increased from 10% to 60% (p<0.05) and helped curb the spread of AHC. Taipei experienced a rapid decrease in AHC cases between the Friday of the SMS announcement and the following Monday, October 15, (0.70% vs. 0.36%). By October 26, AHC cases reduced to 0.01%. The success of this risk communication program in Taipei (as compared to Keelung) is further reflected through rapid improvements in three epidemic indicators: (1) significantly lower crude attack rates (1.95% vs. 14.92%, p<0.001), (2) a short epidemic period of AHC (13 vs. 34 days), and (3) a quick drop in risk level (1∼2 weeks) in Taipei districts that border Keelung (the original domestic epicenter). Conclusions and Significance The timely launch of this systematic, communication

  20. Multi-channel time-reversal receivers for multi and 1-bit implementations

    DOEpatents

    Candy, James V.; Chambers, David H.; Guidry, Brian L.; Poggio, Andrew J.; Robbins, Christopher L.

    2008-12-09

    A communication system for transmitting a signal through a channel medium comprising digitizing the signal, time-reversing the digitized signal, and transmitting the signal through the channel medium. In one embodiment a transmitter is adapted to transmit the signal, a multiplicity of receivers are adapted to receive the signal, a digitizer digitizes the signal, and a time-reversal signal processor is adapted to time-reverse the digitized signal. An embodiment of the present invention includes multi bit implementations. Another embodiment of the present invention includes 1-bit implementations. Another embodiment of the present invention includes a multiplicity of receivers used in the step of transmitting the signal through the channel medium.

  1. Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight.

    PubMed

    Elyas, Eli; Grimwood, Alex; Erler, Janine T; Robinson, Simon P; Cox, Thomas R; Woods, Daniel; Clowes, Peter; De Luca, Ramona; Marinozzi, Franco; Fromageau, Jérémie; Bamber, Jeffrey C

    2017-01-01

    Elastography, the imaging of elastic properties of soft tissues, is well developed for macroscopic clinical imaging of soft tissues and can provide useful information about various pathological processes which is complementary to that provided by the original modality. Scaling down of this technique should ply the field of cellular biology with valuable information with regard to elastic properties of cells and their environment. This paper evaluates the potential to develop such a tool by modifying a commercial optical coherence tomography (OCT) device to measure the speed of shear waves propagating in a three-dimensional (3D) medium. A needle, embedded in the gel, was excited to vibrate along its long axis and the displacement as a function of time and distance from the needle associated with the resulting shear waves was detected using four M-mode images acquired simultaneously using a commercial four-channel swept-source OCT system. Shear-wave time of arrival (TOA) was detected by tracking the axial OCT-speckle motion using cross-correlation methods. Shear-wave speed was then calculated from inter-channel differences of TOA for a single burst (the relative TOA method) and compared with the shear-wave speed determined from positional differences of TOA for a single channel over multiple bursts (the absolute TOA method). For homogeneous gels the relative method provided shear-wave speed with acceptable precision and accuracy when judged against the expected linear dependence of shear modulus on gelatine concentration (R2 = 0.95) and ultimate resolution capabilities limited by 184μm inter-channel distance. This overall approach shows promise for its eventual provision as a research tool in cancer cell biology. Further work is required to optimize parameters such as vibration frequency, burst length and amplitude, and to assess the lateral and axial resolutions of this type of device as well as to create 3D elastograms.

  2. Multi-Channel Optical Coherence Elastography Using Relative and Absolute Shear-Wave Time of Flight

    PubMed Central

    Elyas, Eli; Grimwood, Alex; Erler, Janine T.; Robinson, Simon P.; Cox, Thomas R.; Woods, Daniel; Clowes, Peter; De Luca, Ramona; Marinozzi, Franco; Fromageau, Jérémie; Bamber, Jeffrey C.

    2017-01-01

    Elastography, the imaging of elastic properties of soft tissues, is well developed for macroscopic clinical imaging of soft tissues and can provide useful information about various pathological processes which is complementary to that provided by the original modality. Scaling down of this technique should ply the field of cellular biology with valuable information with regard to elastic properties of cells and their environment. This paper evaluates the potential to develop such a tool by modifying a commercial optical coherence tomography (OCT) device to measure the speed of shear waves propagating in a three-dimensional (3D) medium. A needle, embedded in the gel, was excited to vibrate along its long axis and the displacement as a function of time and distance from the needle associated with the resulting shear waves was detected using four M-mode images acquired simultaneously using a commercial four-channel swept-source OCT system. Shear-wave time of arrival (TOA) was detected by tracking the axial OCT-speckle motion using cross-correlation methods. Shear-wave speed was then calculated from inter-channel differences of TOA for a single burst (the relative TOA method) and compared with the shear-wave speed determined from positional differences of TOA for a single channel over multiple bursts (the absolute TOA method). For homogeneous gels the relative method provided shear-wave speed with acceptable precision and accuracy when judged against the expected linear dependence of shear modulus on gelatine concentration (R2 = 0.95) and ultimate resolution capabilities limited by 184μm inter-channel distance. This overall approach shows promise for its eventual provision as a research tool in cancer cell biology. Further work is required to optimize parameters such as vibration frequency, burst length and amplitude, and to assess the lateral and axial resolutions of this type of device as well as to create 3D elastograms. PMID:28107368

  3. Simultaneous multi-channel CMW-band and MMW-band UWB monocycle pulse generation using FWM effect in a highly nonlinear photonic crystal fiber.

    PubMed

    Zhang, Fangzheng; Wu, Jian; Fu, Songnian; Xu, Kun; Li, Yan; Hong, Xiaobin; Shum, Ping; Lin, Jintong

    2010-07-19

    We propose and experimentally demonstrate a scheme to simultaneously realize multi-channel centimeter wave (CMW) band and millimeter wave (MMW) band ultra-wideband (UWB) monocycle pulse generation using four wave mixing (FWM) effect in a highly nonlinear photonic crystal fiber (HNL-PCF). Two lightwaves carrying polarity-reversed optical Gaussian pulses with appropriate time delay and another lightwave carrying a 20 GHz clock signal are launched into the HNL-PCF together. By filtering out the FWM idlers, two CMW-band UWB monocycle signals and two MMW-band UWB monocycle signals at 20 GHz are obtained simultaneously. Experimental measurements of the generated UWB monocycle pulses at individual wavelength, which comply with the FCC regulations, verify the feasibility and flexibility of proposed scheme for use in practical UWB communication systems.

  4. Investigation of verbal and visual working memory by multi-channel time-resolved functional near-infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Contini, D.; Caffini, M.; Re, R.; Zucchelli, L.; Spinelli, L.; Basso Moro, S.; Bisconti, S.; Ferrari, M.; Quaresima, V.; Cutini, S.; Torricelli, A.

    2013-03-01

    Working memory (WM) is fundamental for a number of cognitive processes, such as comprehension, reasoning and learning. WM allows the short-term maintenance and manipulation of the information selected by attentional processes. The goal of this study was to examine by time-resolved fNIRS neural correlates of the verbal and visual WM during forward and backward digit span (DF and DB, respectively) tasks, and symbol span (SS) task. A neural dissociation was hypothesised between the maintenance and manipulation processes. In particular, a dorsolateral/ventrolateral prefrontal cortex (DLPFC/VLPFC) recruitment was expected during the DB task, whilst a lateralised involvement of Brodmann Area (BA) 10 was expected during the execution of the DF task. Thirteen subjects were monitored by a multi-channel, dual-wavelength (690 and 829 nm) time-resolved fNIRS system during 3 minutes long DF and DB tasks and 4 minutes long SS task. The participants' mean memory span was calculated for each task: DF: 6.46+/-1.05 digits; DB: 5.62+/-1.26 digits; SS: 4.69+/-1.32 symbols. No correlation was found between the span level and the heart rate data (measured by pulse oximeter). As expected, DB elicited a broad activated area, in the bilateral VLPFC and the right DLPFC, whereas a more localised activation was observed over the right hemisphere during either DF (BA 10) or SS (BA 10 and 44). The robust involvement of the DLPFC during DB, compared to DF, is compatible with previous findings and with the key role of the central executive subserving in manipulating processes.

  5. Development and application of a multi-channel monitoring system for near real-time VOC measurement in a hazardous waste management facility.

    PubMed

    Je, Chung-hwan; Stone, Richard; Oberg, Steven G

    2007-09-01

    This paper describes the development and application of a multi-channel monitoring system for recording, processing, and analyzing volatile organic compound (VOC) levels discharged to the atmosphere from a walk-in hood in a hazardous waste management facility. The monitoring system consists of an array of PID (photo ionization detector) sensors and a networked control program that provides operational schematic diagram, performs data analyses, and illustrates real-time graphical displays. Furthermore, the system records potential worker exposures, exhaust filtration efficiency and environmental release levels. Multi-channel continuous monitoring of VOCs is successfully implemented during chemical bulking operations. It is shown that a real-time monitoring system is effective for early warning detection of hazardous chemicals and for predicting the performance of adsorption filters used for VOC removal. In addition, a connected local weather visualization system supports efforts to minimize potential health and environmental impacts of VOC emissions to surrounding areas.

  6. High-speed, multi-channel detector readout electronics for fast radiation detectors

    SciTech Connect

    Hennig, Wolfgang

    2012-06-22

    In this project, we are developing a high speed digital spectrometer that a) captures detector waveforms at rates up to 500 MSPS b) has upgraded event data acquisition with additional data buffers for zero dead time operation c) moves energy calculations to the FPGA to increase spectrometer throughput in fast scintillator applications d) uses a streamlined architecture and high speed data interface for even faster readout to the host PC These features are in addition to the standard functions in our existing spectrometers such as digitization, programmable trigger and energy filters, pileup inspection, data acquisition with energy and time stamps, MCA histograms, and run statistics. In Phase I, we upgraded one of our existing spectrometer designs to demonstrate the key principle of fast waveform capture using a 500 MSPS, 12 bit ADC and a Xilinx Virtex-4 FPGA. This upgraded spectrometer, named P500, performed well in initial tests of energy resolution, pulse shape analysis, and timing measurements, thus achieving item (a) above. In Phase II, we are revising the P500 to build a commercial prototype with the improvements listed in items (b)-(d). As described in the previous report, two devices were built to pursue this goal, named the Pixie-500 and the Pixie-500 Express. The Pixie-500 has only minor improvements from the Phase I prototype and is intended as an early commercial product (its production and part of its development were funded outside the SBIR). It also allows testing of the ADC performance in real applications.The Pixie-500 Express (or Pixie-500e) includes all of the improvements (b)-(d). At the end of Phase II of the project, we have tested and debugged the hardware, firmware and software of the Pixie-500 Express prototype boards delivered 12/3/2010. This proved substantially more complex than anticipated. At the time of writing, all hardware bugs have been fixed, the PCI Express interface is working, the SDRAM has been successfully tested and the SHARC

  7. A Multi-Channel Method for Retrieving Surface Temperature for High-Emissivity Surfaces from Hyperspectral Thermal Infrared Images.

    PubMed

    Zhong, Xinke; Labed, Jelila; Zhou, Guoqing; Shao, Kun; Li, Zhao-Liang

    2015-06-08

    The surface temperature (ST) of high-emissivity surfaces is an important parameter in climate systems. The empirical methods for retrieving ST for high-emissivity surfaces from hyperspectral thermal infrared (HypTIR) images require spectrally continuous channel data. This paper aims to develop a multi-channel method for retrieving ST for high-emissivity surfaces from space-borne HypTIR data. With an assumption of land surface emissivity (LSE) of 1, ST is proposed as a function of 10 brightness temperatures measured at the top of atmosphere by a radiometer having a spectral interval of 800-1200 cm(-1) and a spectral sampling frequency of 0.25 cm(-1). We have analyzed the sensitivity of the proposed method to spectral sampling frequency and instrumental noise, and evaluated the proposed method using satellite data. The results indicated that the parameters in the developed function are dependent on the spectral sampling frequency and that ST of high-emissivity surfaces can be accurately retrieved by the proposed method if appropriate values are used for each spectral sampling frequency. The results also showed that the accuracy of the retrieved ST is of the order of magnitude of the instrumental noise and that the root mean square error (RMSE) of the ST retrieved from satellite data is 0.43 K in comparison with the AVHRR SST product.

  8. A Multi-Channel Method for Retrieving Surface Temperature for High-Emissivity Surfaces from Hyperspectral Thermal Infrared Images

    PubMed Central

    Zhong, Xinke; Labed, Jelila; Zhou, Guoqing; Shao, Kun; Li, Zhao-Liang

    2015-01-01

    The surface temperature (ST) of high-emissivity surfaces is an important parameter in climate systems. The empirical methods for retrieving ST for high-emissivity surfaces from hyperspectral thermal infrared (HypTIR) images require spectrally continuous channel data. This paper aims to develop a multi-channel method for retrieving ST for high-emissivity surfaces from space-borne HypTIR data. With an assumption of land surface emissivity (LSE) of 1, ST is proposed as a function of 10 brightness temperatures measured at the top of atmosphere by a radiometer having a spectral interval of 800–1200 cm−1 and a spectral sampling frequency of 0.25 cm−1. We have analyzed the sensitivity of the proposed method to spectral sampling frequency and instrumental noise, and evaluated the proposed method using satellite data. The results indicated that the parameters in the developed function are dependent on the spectral sampling frequency and that ST of high-emissivity surfaces can be accurately retrieved by the proposed method if appropriate values are used for each spectral sampling frequency. The results also showed that the accuracy of the retrieved ST is of the order of magnitude of the instrumental noise and that the root mean square error (RMSE) of the ST retrieved from satellite data is 0.43 K in comparison with the AVHRR SST product. PMID:26061199

  9. Highly Sensitive Multi-Channel IDC Sensor Array for Low Concentration Taste Detection

    PubMed Central

    Khan, Md. Rajibur Rahaman; Kang, Shin-Won

    2015-01-01

    In this study, we designed and developed an interdigitated capacitor (IDC)-based taste sensor array to detect different taste substances. The designed taste sensing array has four IDC sensing elements. The four IDC taste sensing elements of the array are fabricated by incorporating four different types of lipids into the polymer, dioctyl phenylphosphonate (DOPP) and tetrahydrofuran (THF) to make the respective dielectric materials that are individually placed onto an interdigitated electrode (IDE) via spin coating. When the dielectric material of an IDC sensing element comes into contact with a taste substance, its dielectric properties change with the capacitance of the IDC sensing element; this, in turn, changes the voltage across the IDC, as well as the output voltage of each channel of the system. In order to assess the effectiveness of the sensing system, four taste substances, namely sourness (HCl), saltiness (NaCl), sweetness (glucose) and bitterness (quinine-HCl), were tested. The IDC taste sensor array had rapid response and recovery times of about 12.9 s and 13.39 s, respectively, with highly stable response properties. The response property of the proposed IDC taste sensor array was linear, and its correlation coefficient R2 was about 0.9958 over the dynamic range of the taste sensor array as the taste substance concentration was varied from 1 μM to 1 M. The proposed IDC taste sensor array has several other advantages, such as real-time monitoring capabilities, high sensitivity 45.78 mV/decade, good reproducibility with a standard deviation of about 0.029 and compactness, and the circuitry is based on readily available and inexpensive electronic components. The proposed IDC taste sensor array was compared with the potentiometric taste sensor with respect to sensitivity, dynamic range width, linearity and response time. We found that the proposed IDC sensor array has better performance. Finally, principal component analysis (PCA) was applied to

  10. A Generic Framework for Real-Time Multi-Channel Neuronal Signal Analysis, Telemetry Control, and Sub-Millisecond Latency Feedback Generation

    PubMed Central

    Zrenner, Christoph; Eytan, Danny; Wallach, Avner; Thier, Peter; Marom, Shimon

    2010-01-01

    Distinct modules of the neural circuitry interact with each other and (through the motor-sensory loop) with the environment, forming a complex dynamic system. Neuro-prosthetic devices seeking to modulate or restore CNS function need to interact with the information flow at the level of neural modules electrically, bi-directionally and in real-time. A set of freely available generic tools is presented that allow computationally demanding multi-channel short-latency bi-directional interactions to be realized in in vivo and in vitro preparations using standard PC data acquisition and processing hardware and software (Mathworks Matlab and Simulink). A commercially available 60-channel extracellular multi-electrode recording and stimulation set-up connected to an ex vivo developing cortical neuronal culture is used as a model system to validate the method. We demonstrate how complex high-bandwidth (>10 MBit/s) neural recording data can be analyzed in real-time while simultaneously generating specific complex electrical stimulation feedback with deterministically timed responses at sub-millisecond resolution. PMID:21060803

  11. Multi-channel analysis of surface waves MASW of models with high shear-wave velocity contrast

    USGS Publications Warehouse

    Ivanov, J.; Miller, R.D.; Peterie, S.; Zeng, C.; Xia, J.; Schwenk, T.

    2011-01-01

    We use the multi-channel analysis of surface waves MASW method to analyze synthetic seismic data calculated using models with high shear-wave velocity Vs contrast. The MASW dispersion-curve images of the Rayleigh wave are obtained using various sets of source-offset and spread-size configurations from the synthetic seismic data and compared with the theoretically calculated fundamental- and higher-mode dispersion-curves. Such tests showed that most of the dispersion-curve images are dominated by higher-mode energy at the low frequencies, especially when analyzing data from long receiver offsets and thus significantly divert from numerically expected dispersion-curve trends, which can lead to significant Vs overestimation. Further analysis showed that using data with relatively short spread lengths and source offsets can image the desired fundamental-mode of the Rayleigh wave that matches the numerically expected dispersion-curve pattern. As a result, it was concluded that it might be possible to avoid higher-mode contamination at low frequencies at sites with high Vs contrast by appropriate selection of spread size and seismic source offset. ?? 2011 Society of Exploration Geophysicists.

  12. High speed, multi-channel, user programmable digital data acquisition system.

    SciTech Connect

    Sabourov, Konstantin; Hennig, Wolfgang; Walby, Mark

    2013-11-18

    As applications for radiation detection become more demanding, and in turn improvements are made in the technology of radiation detection, there is a need for high speed digital detector readout electronics matching these improvements. Specifically, full control over the on-line processing resources of modern digital electronics is desirable so that researchers can develop custom algorithms for special applications.In the proposed effort, the 500 MHz digital readout electronics previously developed by our company will be redesigned to allow user access to the on-line processing resources. In Phase I, the division of online processing into vendor and user firmware sections has been studied on existing hardware. In Phase II, the hardware will be upgraded to better facilitate the division, and the firmware will be restructured into a robust vendor logic block (providing standard functions such as host I/O, on-board memory I/O, energy computation, MCA spectra, timestamps, waveform capture, run statistics, and triggering and timing) and a user logic block for custom algorithms (with templates and examples for frequently used functions). Investigating several options to divide online processing, it was determined that the most promising approach is to “partition” a single FPGA integrated circuit into a vendor and user section, which is supported in newer devices. The analog front end of the existing electronics proved suitable for most applications, in particular high rate measurements with germanium detectors. The design architecture for new electronics was developed, combining one of the new FPGA device with the analog front end.

  13. High-resolution multi-channel seismic images of the Queen Charlotte Fault system offshore southeastern Alaska

    NASA Astrophysics Data System (ADS)

    Miller, N. C.; Brothers, D. S.; Kluesner, J.; Balster-Gee, A.; Ten Brink, U. S.; Andrews, B. D.; Haeussler, P. J.; Watt, J. T.; Dartnell, P.; East, A. E.

    2016-12-01

    We present high-resolution multi-channel seismic (MCS) images of fault structure and sedimentary stratigraphy along the southeastern Alaska margin, where the northern Queen Charlotte Fault (QCF) cuts the shelf-edge and slope. The QCF is a dominantly strike slip system that forms the boundary between the Pacific (PA) and North American (NA) plates offshore western Canada and southeastern Alaska. The data were collected using a 64 channel, 200 m digital streamer and a 0.75-3 kJ sparker source aboard the R/V Norseman in August 2016. The survey was designed to cross a seafloor fault trace recently imaged by multibeam sonar (see adjacent poster by Brothers et al.) and to extend the subsurface information landward and seaward from the fault. Analysis of these MCS and multibeam data focus on addressing key questions that have significant implications for the kinematic and geodynamic history of the fault, including: Is the imaged surface fault in multibeam sonar the only recently-active fault trace? What is the shallow fault zone width and structure, is the internal structure of the recently-discovered pull-apart basin a dynamically developing structure? How does sediment thickness vary along the margin and how does this variation affect the fault expression? Can previous glacial sequences be identified in the stratigraphy?

  14. Imaging a soil fragipan using a high-frequency multi-channel analysis of surface wave method

    NASA Astrophysics Data System (ADS)

    Lu, Zhiqu; Wilson, Glenn V.

    2017-08-01

    The objective of this study was to noninvasively image fragipan layers using a high-frequency multi-channel analysis of surface wave (HF-MASW) method. The HF-MASW method is developed to measure the soil profile in terms of the shear wave velocity at depths up to a few meters in the vadose zone. The present MASW method uses an accelerometer as a vibration sensor to detect Rayleigh wave propagation generated by an electrodynamic shaker operating in a frequency-sweeping mode in three overlapped frequency bands. With the method, a subsurface image was obtained, i.e., the soil properties in terms of shear wave velocity of a vertical cross-section of the test site were measured, visualized, and evaluated. From the contrast of the image, the presence, depth, and extent of a fragipan were identified. The HF-MASW result was compared with field observations of a soil pit face and a 2-dimensional image obtained by penetration tests. They were in good agreement. The study demonstrated the capability of the HF-MASW technique for detection and imaging soil subsurface hard layers such as fragipan.

  15. High-Speed, Multi-Channel Serial ADC LVDS Interface for Xilinx Virtex-5 FPGA

    NASA Technical Reports Server (NTRS)

    Taylor, Gregory H.

    2012-01-01

    Analog-to-digital converters (ADCs) are used in scientific and communications instruments on all spacecraft. As data rates get higher, and as the transition is made from parallel ADC designs to high-speed, serial, low-voltage differential signaling (LVDS) designs, the need will arise to interface these in field programmable gate arrays (FPGAs). As Xilinx has released the radiation-hardened version of the Virtex-5, this will likely be used in future missions. High-speed serial ADCs send data at very high rates. A de-serializer instantiated in the fabric of the FPGA could not keep up with these high data rates. The Virtex-5 contains primitives designed specifically for high-speed, source-synchronous de-serialization, but as supported by Xilinx, can only support bitwidths of 10. Supporting bit-widths of 12 or more requires the use of the primitives in an undocumented configuration, a non-trivial task. A new SystemVerilog design was written that is simpler and uses fewer hardware resources than the reference design described in Xilinx Application Note XAPP866. It has been shown to work in a Xilinx XC5VSX24OT connected to a MAXIM MAX1438 12-bit ADC using a 50-MHz sample clock. The design can be replicated in the FPGA for multiple ADCs (four instantiations were used for a total of 28 channels).

  16. Multi-channel electronic and vibrational dynamics in polyatomic resonant high-order harmonic generation

    PubMed Central

    Ferré, A.; Boguslavskiy, A. E.; Dagan, M.; Blanchet, V.; Bruner, B. D.; Burgy, F.; Camper, A.; Descamps, D.; Fabre, B.; Fedorov, N.; Gaudin, J.; Geoffroy, G.; Mikosch, J.; Patchkovskii, S.; Petit, S.; Ruchon, T.; Soifer, H.; Staedter, D.; Wilkinson, I.; Stolow, A.; Dudovich, N.; Mairesse, Y.

    2015-01-01

    High-order harmonic generation in polyatomic molecules generally involves multiple channels of ionization. Their relative contribution can be strongly influenced by the presence of resonances, whose assignment remains a major challenge for high-harmonic spectroscopy. Here we present a multi-modal approach for the investigation of unaligned polyatomic molecules, using SF6 as an example. We combine methods from extreme-ultraviolet spectroscopy, above-threshold ionization and attosecond metrology. Fragment-resolved above-threshold ionization measurements reveal that strong-field ionization opens at least three channels. A shape resonance in one of them is found to dominate the signal in the 20–26 eV range. This resonance induces a phase jump in the harmonic emission, a switch in the polarization state and different dynamical responses to molecular vibrations. This study demonstrates a method for extending high-harmonic spectroscopy to polyatomic molecules, where complex attosecond dynamics are expected. PMID:25608712

  17. Multi-channel electronic and vibrational dynamics in polyatomic resonant high-order harmonic generation

    NASA Astrophysics Data System (ADS)

    Ferré, A.; Boguslavskiy, A. E.; Dagan, M.; Blanchet, V.; Bruner, B. D.; Burgy, F.; Camper, A.; Descamps, D.; Fabre, B.; Fedorov, N.; Gaudin, J.; Geoffroy, G.; Mikosch, J.; Patchkovskii, S.; Petit, S.; Ruchon, T.; Soifer, H.; Staedter, D.; Wilkinson, I.; Stolow, A.; Dudovich, N.; Mairesse, Y.

    2015-01-01

    High-order harmonic generation in polyatomic molecules generally involves multiple channels of ionization. Their relative contribution can be strongly influenced by the presence of resonances, whose assignment remains a major challenge for high-harmonic spectroscopy. Here we present a multi-modal approach for the investigation of unaligned polyatomic molecules, using SF6 as an example. We combine methods from extreme-ultraviolet spectroscopy, above-threshold ionization and attosecond metrology. Fragment-resolved above-threshold ionization measurements reveal that strong-field ionization opens at least three channels. A shape resonance in one of them is found to dominate the signal in the 20-26 eV range. This resonance induces a phase jump in the harmonic emission, a switch in the polarization state and different dynamical responses to molecular vibrations. This study demonstrates a method for extending high-harmonic spectroscopy to polyatomic molecules, where complex attosecond dynamics are expected.

  18. Multi-Channel High-Tc SQUID Detection System for Metallic Contaminants

    NASA Astrophysics Data System (ADS)

    Kitamura, Yoshihiro; Hatsukade, Yoshimi; Tanaka, Saburo; Ohtani, Takeyoshi; Suzuki, Shuichi

    Finding ultra-small metallic contaminants is a big issue for manufacturers of lithium-ion batteries nowadays. Therefore, we have developed high-Tc SQUID systems for detection of such fine magnetic metallic contaminants. In this paper, we constructed an eight channel high-Tc SQUID gradiometer system for inspection of a sheet electrode of a lithium ion battery with width of about 70 mm. By this system, a small iron ball of about 30 μm in diameter was successfully detected. It is shown that this system has a detectable range of 70 mm in width. These results suggest that the system is a promising tool for the detection of the contaminants in lithium ion batteries.

  19. Metallic contaminant detection system using multi-channel high Tc SQUIDs

    NASA Astrophysics Data System (ADS)

    Tanaka, Saburo; Kitamura, Yoshihiro; Hatsukade, Yoshimi; Ohtani, Takeyoshi; Suzuki, Shuichi

    2012-10-01

    We have developed the magnetic metallic contaminant detectors using multiple high Tc SQUID gradiometers for industrial products. Finding ultra-small metallic contaminants is a big issue for manufacturers producing commercial products. The quality of industrial products such as lithium ion batteries can deteriorate by the inclusion of tiny metallic contaminants. When the contamination does occur, the manufacturer of the product suffers a great loss to recall the tainted products. Metallic particles with outer dimension less than 50 μm cannot be detected by a conventional X-ray imaging. Therefore a high sensitive detection system for small foreign matters is required. However, in most of the cases, the matrix of an active material coated sheet electrode is magnetized and the magnetic signal from the matrix is large enough to mask the signal from contaminants. Thus we have developed a detection system based on a SQUID gradiometer and a horizontal magnetization to date. For practical use, we should increase the detection width of the system by employing multiple sensors. We successfully realized an eight-channel high-Tc SQUID gradiometer system for inspection of sheet electrodes of a lithium ion battery with width of at least 60 to 70 mm. Eight planar SQUID gradiometers were mounted with a separation of 9.0 mm. As a result, small iron particles of less than 50 μm were successfully measured. This result suggests that the system is a promising tool for the detection of contaminants in a lithium ion battery.

  20. Design of a Multi-Channel Ultra-High Resolution Superconducting Gamma-Ray Spectrometer

    SciTech Connect

    Friedrich, S; Terracol, S F; Miyazaki, T; Drury, O B; Ali, Z A; Cunningham, M F; Niedermayr, T R; Barbee Jr., T W; Batteux, J D; Labov, S E

    2004-11-29

    Superconducting Gamma-ray microcalorimeters operated at temperatures around {approx}0.1 K offer an order of magnitude improvement in energy resolution over conventional high-purity Germanium spectrometers. The calorimeters consist of a {approx}1 mm{sup 3} superconducting or insulating absorber and a sensitive thermistor, which are weakly coupled to a cold bath. Gamma-ray capture increases the absorber temperature in proportion to the Gamma-ray energy, this is measured by the thermistor, and both subsequently cool back down to the base temperature through the weak link. We are developing ultra-high-resolution Gamma-ray spectrometers based on Sn absorbers and superconducting Mo/Cu multilayer thermistors for nuclear non-proliferation applications. They have achieved an energy resolution between 60 and 90 eV for Gamma-rays up to 100 keV. We also build two-stage adiabatic demagnetization refrigerators for user-friendly detector operation at 0.1 K. We present recent results on the performance of single pixel Gamma-ray spectrometers, and discuss the design of a large detector array for increased sensitivity.

  1. TARGET: A multi-channel digitizer chip for very-high-energy gamma-ray telescopes

    SciTech Connect

    Bechtol, K.; Funk, S.; Okumura, A.; Ruckman, L.; Simons, A.; Tajima, H.; Vandenbroucke, J.; Varner, G.; /Hawaii U.

    2011-08-11

    The next-generation very-high-energy (VHE) gamma-ray observatory, the Cherenkov Telescope Array, will feature dozens of imaging atmospheric Cherenkov telescopes (IACTs), each with thousands of pixels of photosensors. To be affordable and reliable, reading out such a mega-channel array requires event recording technology that is highly integrated and modular, with a low cost per channel. We present the design and performance of a chip targeted to this application: the TeV Array Readout with GSa/s sampling and Event Trigger (TARGET). This application-specific integrated circuit (ASIC) has 16 parallel input channels, a 4096-sample buffer for each channel, adjustable input termination, self-trigger functionality, and tight window-selected readout. We report the performance of TARGET in terms of sampling frequency, power consumption, dynamic range, current-mode gain, analog bandwidth, and cross talk. The large number of channels per chip allows a low cost per channel ($10 to $20 including front-end and back-end electronics but not including photosensors) to be achieved with a TARGET-based IACT readout system. In addition to basic performance parameters of the TARGET chip itself, we present a camera module prototype as well as a second-generation chip (TARGET 2), both of which have been produced.

  2. Multi-channel microstrip transceiver arrays using harmonics for high field MR imaging in humans.

    PubMed

    Wu, Bing; Wang, Chunsheng; Lu, Jonathan; Pang, Yong; Nelson, Sarah J; Vigneron, Daniel B; Zhang, Xiaoliang

    2012-02-01

    Radio-frequency (RF) transceiver array design using primary and higher order harmonics for in vivo parallel magnetic resonance imaging imaging (MRI) and spectroscopic imaging is proposed. The improved electromagnetic decoupling performance, unique magnetic field distributions and high-frequency operation capabilities of higher-order harmonics of resonators would benefit transceiver arrays for parallel MRI, especially for ultrahigh field parallel MRI. To demonstrate this technique, microstrip transceiver arrays using first and second harmonic resonators were developed for human head parallel imaging at 7T. Phantom and human head images were acquired and evaluated using the GRAPPA reconstruction algorithm. The higher-order harmonic transceiver array design technique was also assessed numerically using FDTD simulation. Compared with regular primary-resonance transceiver designs, the proposed higher-order harmonic technique provided an improved g-factor and increased decoupling among resonant elements without using dedicated decoupling circuits, which would potentially lead to a better parallel imaging performance and ultimately faster and higher quality imaging. The proposed technique is particularly suitable for densely spaced transceiver array design where the increased mutual inductance among the elements becomes problematic. In addition, it also provides a simple approach to readily upgrade the channels of a conventional primary resonator microstrip array to a larger number for faster imaging.

  3. Multi-Channel Microstrip Transceiver Arrays Using Harmonics for High Field MR Imaging in Humans

    PubMed Central

    Wu, Bing; Wang, Chunsheng; Lu, Jonathan; Pang, Yong; Nelson, Sarah J; Vigneron, Daniel B; Zhang, Xiaoliang

    2012-01-01

    RF transceiver array design using primary and higher order harmonics for in-vivo parallel MR imaging and spectroscopic imaging is proposed. The improved electromagnetic decoupling performance, unique magnetic field distributions and high-frequency operation capabilities of higher-order harmonics of resonators would benefit transceiver arrays for parallel MRI, especially for ultrahigh field parallel MRI. To demonstrate this technique, microstrip transceiver arrays using first and second harmonic resonators were developed for human head parallel imaging at 7T. Phantom and human head images were acquired and evaluated using the GRAPPA reconstruction algorithm. The higher-order harmonic transceiver array design technique was also assessed numerically using FDTD simulation. Compared with regular primary-resonance transceiver designs, the proposed higher-order harmonic technique provided an improved g-factor and increased decoupling among resonant elements without using dedicated decoupling circuits, which would potentially lead to a better parallel imaging performance and ultimately faster and higher quality imaging. The proposed technique is particularly suitable for densely spaced transceiver array design where the increased mutual inductance among the elements becomes problematic. In addition, it also provides a simple approach to readily upgrade the channels of a conventional primary resonator microstrip array to a larger number for faster imaging. PMID:21878410

  4. An efficient VLSI implementation of on-line recursive ICA processor for real-time multi-channel EEG signal separation.

    PubMed

    Shih, Wei-Yeh; Liao, Jui-Chieh; Huang, Kuan-Ju; Fang, Wai-Chi; Cauwenberghs, Gert; Jung, Tzyy-Ping

    2013-01-01

    This paper presents an efficient VLSI implementation of on-line recursive ICA (ORICA) processor for real-time multi-channel EEG signal separation. The proposed design contains a system control unit, a whitening unit, a singular value decomposition unit, a floating matrix multiply unit and, and an ORICA weight training unit. Because the input sample rate of the ORICA processor is 128 Hz, the ORICA processor should produce independent components before the next sample is input in 1/128 s. Under the timing constraints of commutating multi-channel ORICA in real time, the design of the ORICA processor is a mixed architecture, which is designed as different hardware parallelism according to the complexity of processing units. The shared arithmetic processing unit and shared register can reduce hardware complexity and power consumption. The proposed design is implemented used TSMC 90 nm CMOS technology with 8-channel EEG processing in 128 Hz sample rate of raw data and consumes 2.827 mW at 50 MHz clock rate. The performance of the proposed design is also shown to reach 0.0078125 s latency after each EEG sample time, and the average correlation coefficient between the original source signals and extracted ORICA signals for each 1 s frame is 0.9763.

  5. Generation of multi-channel high-speed physical random numbers originated from two chaotic signals of mutually coupled semiconductor lasers

    NASA Astrophysics Data System (ADS)

    Tang, X.; Wu, Z. M.; Wu, J. G.; Deng, T.; Fan, L.; Zhong, Z. Q.; Chen, J. J.; Xia, G. Q.

    2015-01-01

    We propose and experimentally demonstrate a novel technique to generate multi-channel high-speed physical random numbers (PRNs) by taking two chaotic signal outputs from mutually coupled semiconductor lasers (MC-SLs) as entropy sources. First, through controlling the operation parameters of the MC-SL system, two time-delay signature (TDS) suppressed chaotic signals can be obtained. Next, each of these two chaotic signals is sampled by an 8 bit analog-to-digital converter (ADC) with a sampling rate of 10 GHz, and then a bitwise exclusive-OR (XOR) operation on the corresponding bits in samples of the chaotic signal and its time delayed signal is implemented to obtain 8 bit XOR data. Furthermore, through selecting the five least significant bits (LSBs) of 8 bit XOR data to form 5 bit Boolean sequences, two sets of PRN streams with a rate up to 50 Gbits s-1 are generated and successfully pass the NIST statistical tests. Finally, merging these two sets of 50 Gbits s-1 PRN streams by an interleaving operation, another set of the 100 Gbits s-1 PRN stream, which meets all the quality criteria of NIST statistical tests, is also acquired.

  6. Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

    PubMed Central

    Xu, Shicai; Zhan, Jian; Man, Baoyuan; Jiang, Shouzhen; Yue, Weiwei; Gao, Shoubao; Guo, Chengang; Liu, Hanping; Li, Zhenhua; Wang, Jihua; Zhou, Yaoqi

    2017-01-01

    Reliable determination of binding kinetics and affinity of DNA hybridization and single-base mismatches plays an essential role in systems biology, personalized and precision medicine. The standard tools are optical-based sensors that are difficult to operate in low cost and to miniaturize for high-throughput measurement. Biosensors based on nanowire field-effect transistors have been developed, but reliable and cost-effective fabrication remains a challenge. Here, we demonstrate that a graphene single-crystal domain patterned into multiple channels can measure time- and concentration-dependent DNA hybridization kinetics and affinity reliably and sensitively, with a detection limit of 10 pM for DNA. It can distinguish single-base mutations quantitatively in real time. An analytical model is developed to estimate probe density, efficiency of hybridization and the maximum sensor response. The results suggest a promising future for cost-effective, high-throughput screening of drug candidates, genetic variations and disease biomarkers by using an integrated, miniaturized, all-electrical multiplexed, graphene-based DNA array. PMID:28322227

  7. Real-time reliable determination of binding kinetics of DNA hybridization using a multi-channel graphene biosensor

    NASA Astrophysics Data System (ADS)

    Xu, Shicai; Zhan, Jian; Man, Baoyuan; Jiang, Shouzhen; Yue, Weiwei; Gao, Shoubao; Guo, Chengang; Liu, Hanping; Li, Zhenhua; Wang, Jihua; Zhou, Yaoqi

    2017-03-01

    Reliable determination of binding kinetics and affinity of DNA hybridization and single-base mismatches plays an essential role in systems biology, personalized and precision medicine. The standard tools are optical-based sensors that are difficult to operate in low cost and to miniaturize for high-throughput measurement. Biosensors based on nanowire field-effect transistors have been developed, but reliable and cost-effective fabrication remains a challenge. Here, we demonstrate that a graphene single-crystal domain patterned into multiple channels can measure time- and concentration-dependent DNA hybridization kinetics and affinity reliably and sensitively, with a detection limit of 10 pM for DNA. It can distinguish single-base mutations quantitatively in real time. An analytical model is developed to estimate probe density, efficiency of hybridization and the maximum sensor response. The results suggest a promising future for cost-effective, high-throughput screening of drug candidates, genetic variations and disease biomarkers by using an integrated, miniaturized, all-electrical multiplexed, graphene-based DNA array.

  8. Real-time multi-channel monitoring of burst-suppression using neural network technology during pediatric status epilepticus treatment.

    PubMed

    Papadelis, Christos; Ashkezari, Seyedeh Fatemeh Salimi; Doshi, Chiran; Thome-Souza, Sigride; Pearl, Phillip L; Grant, P Ellen; Tasker, Robert C; Loddenkemper, Tobias

    2016-08-01

    To develop a real-time monitoring system that has the potential to guide the titration of anesthetic agents in the treatment of pediatric status epilepticus (SE). We analyzed stored multichannel electroencephalographic (EEG) data collected from 12 pediatric patients with generalized SE. EEG recordings were initially segmented in 500ms time-windows. Features characterizing the power, frequency, and entropy of the signal were extracted from each segment. The segments were annotated as bursts (B), suppressions (S), or artifacts (A) by two electroencephalographers. The EEG features together with the annotations were inputted in a three-layer feed forward neural network (NN). The sensitivity and specificity of NNs with different architectures and training algorithms to classify segments into B, S, or A were estimated. The maximum sensitivity (95.96% for B, 89.25% for S, and 75% for A) and specificity (89.36 for B, 96.26% for S, and 99.8% for A) was observed for the NN with 10 nodes in the hidden layer. By using this NN, we designed a real-time system that estimates the burst-suppression index (BSI). Our system provides a reliable real-time estimate of multichannel BSI requiring minimal memory and computation time. The system has the potential to assist intensive care unit attendants in the continuous EEG monitoring. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  9. Mapping of calf muscle oxygenation and haemoglobin content during dynamic plantar flexion exercise by multi-channel time-resolved near-infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Torricelli, Alessandro; Quaresima, Valentina; Pifferi, Antonio; Biscotti, Giovanni; Spinelli, Lorenzo; Taroni, Paola; Ferrari, Marco; Cubeddu, Rinaldo

    2004-03-01

    A compact and fast multi-channel time-resolved near-infrared spectroscopy system for tissue oximetry was developed. It employs semiconductor laser and fibre optics for delivery of optical signals. Photons are collected by eight 1 mm fibres and detected by a multianode photomultiplier. A time-correlated single photon counting board is used for the parallel acquisition of time-resolved reflectance curves. Estimate of the reduced scattering coefficient is achieved by fitting with a standard model of diffusion theory, while the modified Lambert-Beer law is used to assess the absorption coefficient. In vivo measurements were performed on five healthy volunteers to monitor spatial changes in calf muscle (medial and lateral gastrocnemius; MG, LG) oxygen saturation (SmO2) and total haemoglobin concentration (tHb) during dynamic plantar flexion exercise performed at 50% of the maximal voluntary contraction. At rest SmO2 was 73.0 ± 0.9 and 70.5 ± 1.7% in MG and LG, respectively (P = 0.045). At the end of the exercise, SmO2 decreased (69.1 ± 1.8 and 63.8 ± 2.1% in MG and LG, respectively; P < 0.01). The LG desaturation was greater than the MG desaturation (P < 0.02). These results strengthen the role of time-resolved near-infrared spectroscopy as a powerful tool for investigating the spatial and temporal features of muscle SmO2 and tHb.

  10. Fast, multi-channel real-time processing of signals with microsecond latency using graphics processing units

    NASA Astrophysics Data System (ADS)

    Rath, N.; Kato, S.; Levesque, J. P.; Mauel, M. E.; Navratil, G. A.; Peng, Q.

    2014-04-01

    Fast, digital signal processing (DSP) has many applications. Typical hardware options for performing DSP are field-programmable gate arrays (FPGAs), application-specific integrated DSP chips, or general purpose personal computer systems. This paper presents a novel DSP platform that has been developed for feedback control on the HBT-EP tokamak device. The system runs all signal processing exclusively on a Graphics Processing Unit (GPU) to achieve real-time performance with latencies below 8 μs. Signals are transferred into and out of the GPU using PCI Express peer-to-peer direct-memory-access transfers without involvement of the central processing unit or host memory. Tests were performed on the feedback control system of the HBT-EP tokamak using forty 16-bit floating point inputs and outputs each and a sampling rate of up to 250 kHz. Signals were digitized by a D-TACQ ACQ196 module, processing done on an NVIDIA GTX 580 GPU programmed in CUDA, and analog output was generated by D-TACQ AO32CPCI modules.

  11. Fast, multi-channel real-time processing of signals with microsecond latency using graphics processing units

    SciTech Connect

    Rath, N. Levesque, J. P.; Mauel, M. E.; Navratil, G. A.; Peng, Q.; Kato, S.

    2014-04-15

    Fast, digital signal processing (DSP) has many applications. Typical hardware options for performing DSP are field-programmable gate arrays (FPGAs), application-specific integrated DSP chips, or general purpose personal computer systems. This paper presents a novel DSP platform that has been developed for feedback control on the HBT-EP tokamak device. The system runs all signal processing exclusively on a Graphics Processing Unit (GPU) to achieve real-time performance with latencies below 8 μs. Signals are transferred into and out of the GPU using PCI Express peer-to-peer direct-memory-access transfers without involvement of the central processing unit or host memory. Tests were performed on the feedback control system of the HBT-EP tokamak using forty 16-bit floating point inputs and outputs each and a sampling rate of up to 250 kHz. Signals were digitized by a D-TACQ ACQ196 module, processing done on an NVIDIA GTX 580 GPU programmed in CUDA, and analog output was generated by D-TACQ AO32CPCI modules.

  12. Fast, multi-channel real-time processing of signals with microsecond latency using graphics processing units.

    PubMed

    Rath, N; Kato, S; Levesque, J P; Mauel, M E; Navratil, G A; Peng, Q

    2014-04-01

    Fast, digital signal processing (DSP) has many applications. Typical hardware options for performing DSP are field-programmable gate arrays (FPGAs), application-specific integrated DSP chips, or general purpose personal computer systems. This paper presents a novel DSP platform that has been developed for feedback control on the HBT-EP tokamak device. The system runs all signal processing exclusively on a Graphics Processing Unit (GPU) to achieve real-time performance with latencies below 8 μs. Signals are transferred into and out of the GPU using PCI Express peer-to-peer direct-memory-access transfers without involvement of the central processing unit or host memory. Tests were performed on the feedback control system of the HBT-EP tokamak using forty 16-bit floating point inputs and outputs each and a sampling rate of up to 250 kHz. Signals were digitized by a D-TACQ ACQ196 module, processing done on an NVIDIA GTX 580 GPU programmed in CUDA, and analog output was generated by D-TACQ AO32CPCI modules.

  13. Multi-channel scanning SQUID microscopy

    NASA Astrophysics Data System (ADS)

    Lee, Su-Young

    I designed, fabricated, assembled, and tested an 8-channel high- Tc scanning SQUID system. I started by modifying an existing single-channel 77 K high-Tc scanning SQUID microscope into a multi-channel system with the goal of reducing the scanning time and improving the spatial resolution by increasing the signal-to-noise ratio S/N. I modified the window assembly, SQUID chip assembly, cold-finger, and vacuum connector. The main concerns for the multi-channel system design were to reduce interaction between channels, to optimize the use of the inside space of the dewar for more than 50 shielded wires, and to achieve good spatial resolution. In the completed system, I obtained the transfer function and the dynamic range (phimax ˜ 11phi0) for each SQUID. At 1kHz, the slew rate is about 3000 phi0/s. I also found that the white noise level varies from 5 muphi0/Hz1/2 to 20 muphi 0/Hz1/2 depending on the SQUID. A new data acquisition program was written that triggered on position and collects data from up to eight SQUIDS. To generate a single image from the multichannel system, I calibrated the tilt of the xy-stage and z-stage manually, rearranged the scanned data by cutting overlapping parts, and determined the applied field by multiplying by the mutual inductance matrix. I found that I could reduce scanning time and improve the image quality by doing so. In addition, I have analyzed and observed the effect of position noise on magnetic field images and used these results to find the position noise in my scanning SQUID microscope. My analysis reveals the relationship between spatial resolution and position noise and that my system was dominated by position noise under typical operating conditions. I found that the smaller the sensor-sample separation, the greater the effect of position noise is on the total effective magnetic field noise and on spatial resolution. By averaging several scans, I found that I could reduce position noise and that the spatial resolution can

  14. Software Compression for Partially Parallel Imaging with Multi-channels.

    PubMed

    Huang, Feng; Vijayakumar, Sathya; Akao, James

    2005-01-01

    In magnetic resonance imaging, multi-channel phased array coils enjoy a high signal to noise ratio (SNR) and better parallel imaging performance. But with the increase in number of channels, the reconstruction time and requirement for computer memory become inevitable problems. In this work, principle component analysis is applied to reduce the size of data and protect the performance of parallel imaging. Clinical data collected using a 32-channel cardiac coil are used in the experiments. Experimental results show that the proposed method dramatically reduces the processing time without much damage to the reconstructed image.

  15. The EarthScope Array Network Facility: application-driven low-latency web-based tools for accessing high-resolution multi-channel waveform data

    NASA Astrophysics Data System (ADS)

    Newman, R. L.; Lindquist, K. G.; Clemesha, A.; Vernon, F. L.

    2008-12-01

    Since April 2004 the EarthScope USArray seismic network has grown to over 400 broadband stations that stream multi-channel data in near real-time to the Array Network Facility in San Diego. Providing secure, yet open, access to real-time and archived data for a broad range of audiences is best served by a series of platform agnostic low-latency web-based applications. We present a framework of tools that interface between the world wide web and Boulder Real Time Technologies Antelope Environmental Monitoring System data acquisition and archival software. These tools provide audiences ranging from network operators and geoscience researchers, to funding agencies and the general public, with comprehensive information about the experiment. This ranges from network-wide to station-specific metadata, state-of-health metrics, event detection rates, archival data and dynamic report generation over a stations two year life span. Leveraging open source web-site development frameworks for both the server side (Perl, Python and PHP) and client-side (Flickr, Google Maps/Earth and jQuery) facilitates the development of a robust extensible architecture that can be tailored on a per-user basis, with rapid prototyping and development that adheres to web-standards.

  16. Packed multi-channels for parallel chromatographic separations in microchips.

    PubMed

    Nagy, Andrea; Gaspar, Attila

    2013-08-23

    Here we report on a simple method to fabricate microfluidic chip incorporating multi-channel systems packed by conventional chromatographic particles without the use of frits. The retaining effectivities of different bottlenecks created in the channels were studied. For the parallel multi-channel chromatographic separations several channel patterns were designed. The obtained multipackings were applied for parallel separations of dyes. The implementation of several chromatographic separation units in microscopic size makes possible faster and high throughput separations.

  17. MULTI-CHANNEL PULSE HEIGHT ANALYZER

    DOEpatents

    Boyer, K.; Johnstone, C.W.

    1958-11-25

    An improved multi-channel pulse height analyzer of the type where the device translates the amplitude of each pulse into a time duration electrical quantity which is utilized to control the length of a train of pulses forwarded to a scaler is described. The final state of the scaler for any one train of pulses selects the appropriate channel in a magnetic memory in which an additional count of one is placed. The improvement consists of a storage feature for storing a signal pulse so that in many instances when two signal pulses occur in rapid succession, the second pulse is preserved and processed at a later time.

  18. Control System for Readout Electronics of Multi-Channel Magnetocardiographs Using High-Temperature DC Superconducting Quantum Interference Devices

    NASA Astrophysics Data System (ADS)

    Kandori, Akihiko; Suzuki, Daisuke; Tsukamoto, Akira; Kumagai, Yukio; Miyashita, Tsuyoshi; Ogata, Kuniomi; Seki, Yusuke; Yokosawa, Koichi; Tsukada, Keiji

    2005-09-01

    We aimed to develop a control system for multichannel magnetocardiography (MCG) based on a high-temperature DC superconducting quantum interference device (high-Tc SQUID). To create this system, we used one oscillator as an AC bias controller to operate a multichannel high-Tc SQUID. To optimize the SQUID parameters (such as the AC bias, offset voltage), two new control sequences based on a cross-correlation method and a fast Fourier transform method were developed. Using the AC bias controller and the sequences, the typical white noise level of the SQUID was about 50--60 fT Hz-1/2 around 100 Hz. Multichannel MCG signals were detected clearly in the system with the SQUIDs. We conclude that our control system with one oscillator and new protocols can reliably operate a multichannel SQUID.

  19. Multi-channel 80-GHz RZ pulse train generation based on parametric process in highly-nonlinear fiber

    NASA Astrophysics Data System (ADS)

    Yang, Jing; Hu, Junhao; Yu, Changyuan; Yeo, Yong Kee; Wang, Yixin

    2010-03-01

    It is experimentally shown that six-channel C + L-band 80-GHz short pulse trains are generated based on parametric process in highly-nonlinear fiber (HNLF). By launching a pulsed pump and three-channel continuous wave (CW) lights into 1-km HNLF, three-channel signals are amplified and three-channel idlers are generated. The waveforms of the generated 80-GHz short pulses are measured by an auto-correlator. The bit-error-rate (BER) of each channel is analyzed numerically. In the back-to-back case, the power penalties of the generated channels are less than 1.5-dB.

  20. Towards optimal multi-channel EMG electrode configurations in muscle force estimation: a high density EMG study.

    PubMed

    Staudenmann, Didier; Kingma, Idsart; Stegeman, Dick F; van Dieën, Jaap H

    2005-02-01

    Surface EMG is an important tool in biomechanics, kinesiology and neurophysiology. In neurophysiology the concept of high-density EMG (HD-EMG), using two dimensional electrode grids, was developed for the measurement of spatiotemporal activation patterns of the underlying muscle and its motor units (MU). The aim of this paper was to determine, with the aid of a HD-EMG grid, the relative importance of a number of electrode sensor configurations for optimizing muscle force estimation. Sensor configurations are distinguished in two categories. The first category concerns dimensions: the size of a single electrode and the inter electrode distance (IED). The second category concerns the sensor's spatial distribution: the total area from which signals are obtained (collection surface) and the number of electrodes per cm(2) (collection density). Eleven subjects performed isometric arm extensions at three elbow angles and three contraction levels. Surface-EMG from the triceps brachii muscle and the external force at the wrist were measured. Compared to a single conventional bipolar electrode pair, the force estimation quality improved by about 30% when using HD-EMG. Among the sensor configurations, the collection surface alone appeared to be responsible for the major part of the EMG based force estimation quality by improving it with 25%.

  1. A multi-channel gel electrophoresis and continuous fraction collection apparatus for high throughput protein separation and characterization

    SciTech Connect

    Choi, Megan; Nordmeyer, Robert A.; Cornell, Earl; Dong, Ming; Biggin, Mark D.; Jin, Jian

    2009-10-02

    To facilitate a direct interface between protein separation by PAGE and protein identification by mass spectrometry, we developed a multichannel system that continuously collects fractions as protein bands migrate off the bottom of gel electrophoresis columns. The device was constructed using several short linear gel columns, each of a different percent acrylamide, to achieve a separation power similar to that of a long gradient gel. A Counter Free-Flow elution technique then allows continuous and simultaneous fraction collection from multiple channels at low cost. We demonstrate that rapid, high-resolution separation of a complex protein mixture can be achieved on this system using SDS-PAGE. In a 2.5 h electrophoresis run, for example, each sample was separated and eluted into 48-96 fractions over a mass range of 10-150 kDa; sample recovery rates were 50percent or higher; each channel was loaded with up to 0.3 mg of protein in 0.4 mL; and a purified band was eluted in two to three fractions (200 L/fraction). Similar results were obtained when running native gel electrophoresis, but protein aggregation limited the loading capacity to about 50 g per channel and reduced resolution.

  2. A multi-channel coronal spectrophotometer.

    NASA Technical Reports Server (NTRS)

    Landman, D. A.; Orrall, F. Q.; Zane, R.

    1973-01-01

    We describe a new multi-channel coronal spectrophotometer system, presently being installed at Mees Solar Observatory, Mount Haleakala, Maui. The apparatus is designed to record and interpret intensities from many sections of the visible and near-visible spectral regions simultaneously, with relatively high spatial and temporal resolution. The detector, a thermoelectrically cooled silicon vidicon camera tube, has its central target area divided into a rectangular array of about 100,000 pixels and is read out in a slow-scan (about 2 sec/frame) mode. Instrument functioning is entirely under PDP 11/45 computer control, and interfacing is via the CAMAC system.

  3. Exploring active layer thaw depth and water content dynamics with multi-channel GPR

    NASA Astrophysics Data System (ADS)

    Wollschlaeger, U.; Gerhards, H.; Westermann, S.; Pan, X.; Boike, J.; Schiwek, P.; Yu, Q.; Roth, K.

    2011-12-01

    In permafrost landscapes, the active layer is the highly dynamic uppermost section of the ground where many important hydrological, biological and geomorphological processes take place. Active layer hydrological processes are controlled by many different factors like thaw depth, soil textural properties, vegetation, and snow cover. These may lead to complex runoff patterns that are difficult to estimate from point measurements in boreholes. New multi-channel GPR systems provide the opportunity to non-invasively estimate reflector depth and average volumetric water content of distinct soil layers over distances ranging from some ten meters up to a few kilometers. Due to the abrupt change in dielectric permittivity between frozen and unfrozen ground, multi-channel GPR is a valuable technique for mapping the depth of the frost table along with the volumetric water content of the active layer without the need of laborious drillings or frost probe measurements. Knowing both values, the total amount of water stored in the active layer can be determined which may be used as an estimate of its latent heat content. Time series of measurements allow spatial monitoring of the progression of the thawing front. Multi-channel GPR thus offers new opportunities for monitoring active layer hydrological processes. This presentation will provide a brief introduction of the multi-channel GPR evaluation technique and will present different applications from several permafrost sites.

  4. Web-based multi-channel analyzer

    DOEpatents

    Gritzo, Russ E.

    2003-12-23

    The present invention provides an improved multi-channel analyzer designed to conveniently gather, process, and distribute spectrographic pulse data. The multi-channel analyzer may operate on a computer system having memory, a processor, and the capability to connect to a network and to receive digitized spectrographic pulses. The multi-channel analyzer may have a software module integrated with a general-purpose operating system that may receive digitized spectrographic pulses for at least 10,000 pulses per second. The multi-channel analyzer may further have a user-level software module that may receive user-specified controls dictating the operation of the multi-channel analyzer, making the multi-channel analyzer customizable by the end-user. The user-level software may further categorize and conveniently distribute spectrographic pulse data employing non-proprietary, standard communication protocols and formats.

  5. Handling Deafness Problem of Scheduled Multi-Channel Polling MACs

    NASA Astrophysics Data System (ADS)

    Jiang, Fulong; Liu, Hao; Shi, Longxing

    Combining scheduled channel polling with channel diversity is a promising way for a MAC protocol to achieve high energy efficiency and performance under both light and heavy traffic conditions. However, the deafness problem may cancel out the benefit of channel diversity. In this paper, we first investigate the deafness problem of scheduled multi-channel polling MACs with experiments. Then we propose and evaluate two schemes to handle the deafness problem. Our experiment shows that deafness is a significant reason for performance degradation in scheduled multi-channel polling MACs. A proper scheme should be chosen depending on the traffic pattern and the design objective.

  6. An integrated analog O/E/O link for multi-channel laser neurons

    SciTech Connect

    Nahmias, Mitchell A. Tait, Alexander N.; Tolias, Leonidas; Chang, Matthew P.; Ferreira de Lima, Thomas; Shastri, Bhavin J.; Prucnal, Paul R.

    2016-04-11

    We demonstrate an analog O/E/O electronic link to allow integrated laser neurons to accept many distinguishable, high bandwidth input signals simultaneously. This device utilizes wavelength division multiplexing to achieve multi-channel fan-in, a photodetector to sum signals together, and a laser cavity to perform a nonlinear operation. Its speed outpaces accelerated-time neuromorphic electronics, and it represents a viable direction towards scalable networking approaches.

  7. Multi-channel polarized thermal emitter

    DOEpatents

    Lee, Jae-Hwang; Ho, Kai-Ming; Constant, Kristen P

    2013-07-16

    A multi-channel polarized thermal emitter (PTE) is presented. The multi-channel PTE can emit polarized thermal radiation without using a polarizer at normal emergence. The multi-channel PTE consists of two layers of metallic gratings on a monolithic and homogeneous metallic plate. It can be fabricated by a low-cost soft lithography technique called two-polymer microtransfer molding. The spectral positions of the mid-infrared (MIR) radiation peaks can be tuned by changing the periodicity of the gratings and the spectral separation between peaks are tuned by changing the mutual angle between the orientations of the two gratings.

  8. A Multi-Channel Radar Receiver.

    DTIC Science & Technology

    1985-01-07

    Doppler weather radar I ’Multi-channel radar receiver -,, Dual frequency radar , Polarization...V ~ ’.= :• ’> . . S , . . .. - -. .° , . * . - . -. . . A Multi-Channel Radar Receiver 1. INTRODUCTION The 10-cm Doppler weather radar at AFGL is...cm Dual Frequency Doppler Weather Radar . Part I: The Radar System, AFGL-TR-82- 0321 (I). 4. Ussailis, J.S., Leiker, L.A.. Goodman, R.M. IV.

  9. Acquisition, processing and interpretation of high-resolution seismic data using a small-scale multi-channel system: an example from the Korea Strait inner shelf, south-east Korea

    NASA Astrophysics Data System (ADS)

    Yoo, Dong-Geun; Koo, Nam-Hyung; Lee, Ho-Young; Kim, Byoung-Yeop; Kim, Young-Jun; Cheong, Snons

    2016-10-01

    A high-resolution seismic survey was designed to improve the quality of seismic data and study the evolution of inner shelf deposits off the southern coast of Korea. A 0.5 L air gun and 6- or 8-channel streamer cable with a 5 m group interval were used as a seismic source and receiver system, respectively. Data recording was digitally performed at a shot interval of 2 s and a sample interval of 0.1 ms using a personal computer (PC)-based recording system with an analogue to digital (A/D) converter. In the data processing, deconvolution and static corrections were very effective for improving the data resolution. The data resolution and signal-to-noise (S/N) ratio were improved by using multi-channel digital seismic systems as opposed to a single-channel analogue streamer. The results show that a small-scale multi-channel seismic system is an effective way to investigate late Quaternary deposits. Seismic stratigraphic analysis of the high-resolution seismic profiles revealed that inner shelf deposits, up to 30 m thick, consist of three sedimentary units, which comprise transgressive and highstand systems tracts deposited after the last glacial period. The transgressive systems tract includes two units (I and II) separated by a ravinement surface (RS). The lower Unit I, lying below the RS, consists of estuarine sediments left behind by shoreface erosion during transgression, and represents a paralic component. The upper Unit II, including two sub-units (IIa and IIb), lies above the RS and consists of sand produced by shoreface erosion during landward transgression, which corresponds to a marine component. The uppermost Unit III lies above the maximum flooding surface and consists of thick mud clinoforms of the modern Nakdong and Seomjin subaqueous deltas. This unit likely formed during the recent sea level highstand and represents the highstand systems tract.

  10. A New Approach to Common-View Time Transfer Using All-in-View Multi-Channel GPS and GLONASS Observations

    DTIC Science & Technology

    1997-12-01

    Standards ( CGGTTS ) [4] and adopted at its last meeting in December 1997. For baselines of up to a few thousands of kilometers, there is no need to...permanent reference day for standard times adopted by the CGGTTS . In this case, multichannel receivers will not have to be updated for standhrd times

  11. Multi channel voltage control for fuel cells

    NASA Astrophysics Data System (ADS)

    Heideck, G.; Purmann, M.; Styczynski, Z.

    Cell voltage control is a safe method to evaluate the operation of the single cells even though large efforts are being made to stabilise the behaviour of the fuel cells over the whole operating range. For fully developed systems only voltage control of single cells is necessary, whereas in test benches it is necessary to record data of the voltages during operation. Normally, a lot of cells are combined to a stack so that higher total voltages can be reached. Higher voltages make possible a high efficient transformation from direct current of the stack to alternate current of the public network. Sometimes more than 100 cells are connected together whereby the open circuit voltage of a single cell amounts to approximately 1 V. Therefore, the signal processing chips show a high supply maximum rating or the resolution of the values has to be reduced. This paper presents an economically priced multi channel voltage control for single cells of a PEM-fuel cell in combination with a microprocessor control and was developed at the Chair for Electric Power Networks and Renewable Energy Sources. The developed system can transfer the data of up to 32 single cells in serial connection. The resolution amounts to 10 bits per channel. The module has its own microprocessor, which is responsible for the intermediate storage of the collected data and the transfer to the RS-232 interface. Optionally, the module can be equipped with an LCD-display of 20 × 4 letters where different menus of the measured and calculated values can be indicated. The module is designed for a voltage of 1 V per channel and can be supplied with a direct voltage of between 6 and 24 V from the fuel cell stack.

  12. Multi-channel lock-in amplifier assisted femtosecond time-resolved fluorescence non-collinear optical parametric amplification spectroscopy with efficient rejection of superfluorescence background

    SciTech Connect

    Mao, Pengcheng; Wang, Zhuan; Dang, Wei; Weng, Yuxiang

    2015-12-15

    Superfluorescence appears as an intense background in femtosecond time-resolved fluorescence noncollinear optical parametric amplification spectroscopy, which severely interferes the reliable acquisition of the time-resolved fluorescence spectra especially for an optically dilute sample. Superfluorescence originates from the optical amplification of the vacuum quantum noise, which would be inevitably concomitant with the amplified fluorescence photons during the optical parametric amplification process. Here, we report the development of a femtosecond time-resolved fluorescence non-collinear optical parametric amplification spectrometer assisted with a 32-channel lock-in amplifier for efficient rejection of the superfluorescence background. With this spectrometer, the superfluorescence background signal can be significantly reduced to 1/300–1/100 when the seeding fluorescence is modulated. An integrated 32-bundle optical fiber is used as a linear array light receiver connected to 32 photodiodes in one-to-one mode, and the photodiodes are further coupled to a home-built 32-channel synchronous digital lock-in amplifier. As an implementation, time-resolved fluorescence spectra for rhodamine 6G dye in ethanol solution at an optically dilute concentration of 10{sup −5}M excited at 510 nm with an excitation intensity of 70 nJ/pulse have been successfully recorded, and the detection limit at a pump intensity of 60 μJ/pulse was determined as about 13 photons/pulse. Concentration dependent redshift starting at 30 ps after the excitation in time-resolved fluorescence spectra of this dye has also been observed, which can be attributed to the formation of the excimer at a higher concentration, while the blueshift in the earlier time within 10 ps is attributed to the solvation process.

  13. Multi-channel lock-in amplifier assisted femtosecond time-resolved fluorescence non-collinear optical parametric amplification spectroscopy with efficient rejection of superfluorescence background

    NASA Astrophysics Data System (ADS)

    Mao, Pengcheng; Wang, Zhuan; Dang, Wei; Weng, Yuxiang

    2015-12-01

    Superfluorescence appears as an intense background in femtosecond time-resolved fluorescence noncollinear optical parametric amplification spectroscopy, which severely interferes the reliable acquisition of the time-resolved fluorescence spectra especially for an optically dilute sample. Superfluorescence originates from the optical amplification of the vacuum quantum noise, which would be inevitably concomitant with the amplified fluorescence photons during the optical parametric amplification process. Here, we report the development of a femtosecond time-resolved fluorescence non-collinear optical parametric amplification spectrometer assisted with a 32-channel lock-in amplifier for efficient rejection of the superfluorescence background. With this spectrometer, the superfluorescence background signal can be significantly reduced to 1/300-1/100 when the seeding fluorescence is modulated. An integrated 32-bundle optical fiber is used as a linear array light receiver connected to 32 photodiodes in one-to-one mode, and the photodiodes are further coupled to a home-built 32-channel synchronous digital lock-in amplifier. As an implementation, time-resolved fluorescence spectra for rhodamine 6G dye in ethanol solution at an optically dilute concentration of 10-5M excited at 510 nm with an excitation intensity of 70 nJ/pulse have been successfully recorded, and the detection limit at a pump intensity of 60 μJ/pulse was determined as about 13 photons/pulse. Concentration dependent redshift starting at 30 ps after the excitation in time-resolved fluorescence spectra of this dye has also been observed, which can be attributed to the formation of the excimer at a higher concentration, while the blueshift in the earlier time within 10 ps is attributed to the solvation process.

  14. Time-resolved multi-channel optical system for assessment of brain oxygenation and perfusion by monitoring of diffuse reflectance and fluorescence

    NASA Astrophysics Data System (ADS)

    Milej, D.; Gerega, A.; Kacprzak, M.; Sawosz, P.; Weigl, W.; Maniewski, R.; Liebert, A.

    2014-03-01

    Time-resolved near-infrared spectroscopy is an optical technique which can be applied in tissue oxygenation assessment. In the last decade this method is extensively tested as a potential clinical tool for noninvasive human brain function monitoring and imaging. In the present paper we show construction of an instrument which allows for: (i) estimation of changes in brain tissue oxygenation using two-wavelength spectroscopy approach and (ii) brain perfusion assessment with the use of single-wavelength reflectometry or fluorescence measurements combined with ICG-bolus tracking. A signal processing algorithm based on statistical moments of measured distributions of times of flight of photons is implemented. This data analysis method allows for separation of signals originating from extra- and intracerebral tissue compartments. In this paper we present compact and easily reconfigurable system which can be applied in different types of time-resolved experiments: two-wavelength measurements at 687 and 832 nm, single wavelength reflectance measurements at 760 nm (which is at maximum of ICG absorption spectrum) or fluorescence measurements with excitation at 760 nm. Details of the instrument construction and results of its technical tests are shown. Furthermore, results of in-vivo measurements obtained for various modes of operation of the system are presented.

  15. Shutter array technique for real-time non-invasive extraction of individual channel responses in multi-channel CPV modules

    NASA Astrophysics Data System (ADS)

    Cook, John P. D.; Yandt, Mark D.; Kelly, Michael; Wheeldon, Jeffrey F.; Hinzer, Karin; Schriemer, Henry

    2013-10-01

    Concentrator photovoltaic (CPV) solar energy systems use optics to concentrate direct normal incidence (DNI) sunlight onto multi-junction photovoltaic (MJPV) cells fabricated from III-V compound semiconductors on germanium substrates. The MJPV receiver, which integrates cell and bypass diode, is then mated with its concentrating optic to form a channel, and several such channels form a CPV module, in which the receivers are connected electrically in series. The two ends of the module receiver string are brought out to a single pair of electrical connections, at which point the lightcurrent- voltage (L-I-V) response of the entire module can be tested. With commercial CPV modules commonly sealed against outdoor exposure, there are no other accessible test points, and field installation on trackers further complicates access to performance data. There are many physical phenomena influencing module performance, and in early development and commercialization some of these may not yet be completely under control. Unambiguous diagnosis of such phenomena from one full-module L-I-V curve is problematic. Simple, fast test methods are needed to develop more detailed information from full-module on-tracker testing, without opening up modules in the field. We describe a test protocol, using a simple optical shutter array constructed to fit mechanically over the module. When module L-I-V curves are recorded for each of various combinations of open and closed shutters, the information can be used to identify one or more anomalous channels, and to further identify the kind of anomaly present, such as optical misalignment, conductor failure, series or shunt resistance, and so on. Simulated results from anomaly models can be compared with the measured results to identify the anomalous behaviour. Results herein are compared with direct single-channel measurements to verify the technique. The L-I-V response curves were obtained in continuous real time, an approach found to be more

  16. Precisely synchronous and cascadable multi-channel arbitrary waveform generator.

    PubMed

    Liu, Ke; Tian, Shulin; Guo, Guangkun; Xiao, Yindong

    2017-03-01

    The output bandwidth and the capability to generate multiple analog outputs with accurately adjustable relative phase are important specifications of arbitrary waveform generator (AWG). To increase the output bandwidth, AWG with a multi-memory paralleled direct digital synthesizer structure (DDS) was proposed to break through operating speed limitations of memory and field programmable gate array. But this structure does complicate synchronization of the analog outputs. This paper proposes a structure for synchronization of the outputs of multi-channel high speed AWG that generates arbitrary waveforms using a multi-memory paralleled DDS. Careful distribution of the clock and trigger signals enables elimination of the random initial phase caused by the frequency divider. Based on this structure, a four-channel 600 mega samples per second AWG is designed. An embedded clock synchronization calibration module is designed to eliminate the random phase difference caused by a frequency divider inside a digital-to-analog converter. The AWG provides a 240 MHz bandwidth, 16 mega-samples storage depth, inter-channel initial skew accuracy less than 150 ps, and 0.0001° phase resolution, which can be used to generate two pairs of I/Q signals or a pair of differential I/Q signals for the quadrature modulator. Additionally, more AWGs can be cascaded to obtain more output channels with an output timing skew between adjacent channels of less than 1.6 ns.

  17. Precisely synchronous and cascadable multi-channel arbitrary waveform generator

    NASA Astrophysics Data System (ADS)

    Liu, Ke; Tian, Shulin; Guo, Guangkun; Xiao, Yindong

    2017-03-01

    The output bandwidth and the capability to generate multiple analog outputs with accurately adjustable relative phase are important specifications of arbitrary waveform generator (AWG). To increase the output bandwidth, AWG with a multi-memory paralleled direct digital synthesizer structure (DDS) was proposed to break through operating speed limitations of memory and field programmable gate array. But this structure does complicate synchronization of the analog outputs. This paper proposes a structure for synchronization of the outputs of multi-channel high speed AWG that generates arbitrary waveforms using a multi-memory paralleled DDS. Careful distribution of the clock and trigger signals enables elimination of the random initial phase caused by the frequency divider. Based on this structure, a four-channel 600 mega samples per second AWG is designed. An embedded clock synchronization calibration module is designed to eliminate the random phase difference caused by a frequency divider inside a digital-to-analog converter. The AWG provides a 240 MHz bandwidth, 16 mega-samples storage depth, inter-channel initial skew accuracy less than 150 ps, and 0.0001° phase resolution, which can be used to generate two pairs of I/Q signals or a pair of differential I/Q signals for the quadrature modulator. Additionally, more AWGs can be cascaded to obtain more output channels with an output timing skew between adjacent channels of less than 1.6 ns.

  18. A robust channel-calibration algorithm for multi-channel in azimuth HRWS SAR imaging based on local maximum-likelihood weighted minimum entropy.

    PubMed

    Zhang, Shuang-Xi; Xing, Meng-Dao; Xia, Xiang-Gen; Liu, Yan-Yang; Guo, Rui; Bao, Zheng

    2013-12-01

    High-resolution and wide-swath (HRWS) synthetic aperture radar (SAR) is an essential tool for modern remote sensing. To effectively deal with the contradiction problem between high-resolution and low pulse repetition frequency and obtain an HRWS SAR image, a multi-channel in azimuth SAR system has been adopted in the literature. However, the performance of the Doppler ambiguity suppression via digital beam forming processing suffers the losses from the channel mismatch. In this paper, a robust channel-calibration algorithm based on weighted minimum entropy is proposed for the multi-channel in azimuth HRWS SAR imaging. The proposed algorithm is implemented by a two-step process. 1) The timing uncertainty in each channel and most of the range-invariant channel mismatches in amplitude and phase have been corrected in the pre-processing of the coarse-compensation. 2) After the pre-processing, there is only residual range-dependent channel mismatch in phase. Then, the retrieval of the range-dependent channel mismatch in phase is achieved by a local maximum-likelihood weighted minimum entropy algorithm. The simulated multi-channel in azimuth HRWS SAR data experiment is adopted to evaluate the performance of the proposed algorithm. Then, some real measured airborne multi-channel in azimuth HRWS Scan-SAR data is used to demonstrate the effectiveness of the proposed approach.

  19. Hand Motion Classification Using a Multi-Channel Surface Electromyography Sensor

    PubMed Central

    Tang, Xueyan; Liu, Yunhui; Lv, Congyi; Sun, Dong

    2012-01-01

    The human hand has multiple degrees of freedom (DOF) for achieving high-dexterity motions. Identifying and replicating human hand motions are necessary to perform precise and delicate operations in many applications, such as haptic applications. Surface electromyography (sEMG) sensors are a low-cost method for identifying hand motions, in addition to the conventional methods that use data gloves and vision detection. The identification of multiple hand motions is challenging because the error rate typically increases significantly with the addition of more hand motions. Thus, the current study proposes two new methods for feature extraction to solve the problem above. The first method is the extraction of the energy ratio features in the time-domain, which are robust and invariant to motion forces and speeds for the same gesture. The second method is the extraction of the concordance correlation features that describe the relationship between every two channels of the multi-channel sEMG sensor system. The concordance correlation features of a multi-channel sEMG sensor system were shown to provide a vast amount of useful information for identification. Furthermore, a new cascaded-structure classifier is also proposed, in which 11 types of hand gestures can be identified accurately using the newly defined features. Experimental results show that the success rate for the identification of the 11 gestures is significantly high. PMID:22438703

  20. Enhanced multi-channel model for auditory spectrotemporal integration.

    PubMed

    Oh, Yonghee; Feth, Lawrence L; Hoglund, Evelyn M

    2015-11-01

    In psychoacoustics, a multi-channel model has traditionally been used to describe detection improvement for multicomponent signals. This model commonly postulates that energy or information within either the frequency or time domain is transformed into a probabilistic decision variable across the auditory channels, and that their weighted linear summation determines optimum detection performance when compared to a critical value such as a decision criterion. In this study, representative integration-based channel models, specifically focused on signal-processing properties of the auditory periphery are reviewed (e.g., Durlach's channel model). In addition, major limitations of the previous channel models are described when applied to spectral, temporal, and spectrotemporal integration performance by human listeners. Here, integration refers to detection threshold improvements as the number of brief tone bursts in a signal is increased. Previous versions of the multi-channel model underestimate listener performance in these experiments. Further, they are unable to apply a single processing unit to signals which vary simultaneously in time and frequency. Improvements to the previous channel models are proposed by considering more realistic conditions such as correlated signal responses in the auditory channels, nonlinear properties in system performance, and a peripheral processing unit operating in both time and frequency domains.

  1. Development of a high-speed wavelength-dispersive IBIL analysis and imaging system using a multi-channel photon-counting spectrometer

    NASA Astrophysics Data System (ADS)

    Kada, Wataru; Kawabata, Shunsuke; Satoh, Takahiro; Parajuli, Raj Kumar; Yamada, Naoto; Koka, Masashi; Miura, Kenta; Hanaizumi, Osamu; Kamiya, Tomihiro

    2017-09-01

    A high-speed wavelength-dispersive ion beam induced luminescence (IBIL) detector was demonstrated using a newly developed photon-counting mode spectrometer based on a 32-channel photomultiplier tube (PMT) array combined with a high-efficiency optical grating. An integrated electrical circuit based on a field-programmable gate array was prepared to process 32 individual IBIL signals from different PMT channels. These signal were further processed conventionally by a micro-PIXE analysis system. Individual pulses corresponding to each IBIL photon incident from the PMT array were multiplexed into a single analog chain with different amplitudes corresponding to the channel number of the array. The signal had a pulse width of 2 μs in the amplitude range 0-10 V. The results suggest that the demonstrated IBIL detector can be used to detect differences in IBIL images at multiple wavelengths.

  2. Multi-channeled single chain variable fragment (scFv) based microfluidic device for explosives detection.

    PubMed

    Charles, Paul T; Davis, Jasmine; Adams, André A; Anderson, George P; Liu, Jinny L; Deschamps, Jeffrey R; Kusterbeck, Anne W

    2015-11-01

    The development of explosives detection technologies has increased significantly over the years as environmental and national security agencies implement tighter pollution control measures and methods for improving homeland security. 2, 4, 6-Trinitrotoluene (TNT), known primarily as a component in munitions, has been targeted for both its toxicity and carcinogenic properties that if present at high concentrations can be a detriment to both humans, marine and plant ecosystems. Enabling end users with environmental detection and monitoring systems capable of providing real-time, qualitative and quantitative chemical analysis of these toxic compounds would be extremely beneficial. Reported herein is the development of a multi-channeled microfluidic device immobilized with single chain fragment variable (scFv) recombinant proteins specific for the explosive, TNT. Fluorescence displacement immunoassays performed under constant flow demonstrated trace level sensitivity and specificity for TNT. The utility of three multi-channeled devices immobilized with either (1) scFv recombinant protein, (2) biotinylated-scFv (bt-scFv) and (3) monoclonal anti-TNT (whole IgG molecule) were investigated and compared. Fluorescence dose response curves, crossreactivity measurements and limits of detection (LOD) for TNT were determined. Fluorescence displacement immunoassays for TNT in natural seawater demonstrated detection limits at sub-parts-per-billion levels (0.5 ppb) utilizing the microfluidic device with immobilized bt-scFv. Published by Elsevier B.V.

  3. Anomaly Detection using Multi-channel FLAC for Supporting Diagnosis of ECG

    NASA Astrophysics Data System (ADS)

    Ye, Jiaxing; Kobayashi, Takumi; Murakawa, Masahiro; Higuchi, Tetsuya; Otsu, Nobuyuki

    In this paper, we propose an approach for abnormality detection in multi-channel ECG signals. This system serves as front end to detect the irregular sections in ECG signals, where symptoms may be observed. Thereby, the doctor can focus on only the detected suspected symptom sections, ignoring the disease-free parts. Hence the workload of the inspection by the doctors is significantly reduced and the diagnosis efficiency can be sharply improved. For extracting the predominant characteristics of multi-channel ECG signals, we propose multi-channel Fourier local auto-correlations (m-FLAC) features on multi-channel complex spectrograms. The method characterizes the amplitude and phase information as well as temporal dynamics of the multi-channel ECG signal. At the anomaly detection stage, we employ complex subspace method for statistically modeling the normal (healthy) ECG patterns as in one-class learning. Then, we investigate the input ECG signals by measuring its deviation distance to the trained subspace. The ECG sections with disordered spectral distributions can be effectively discerned based on such distance metric. To validate the proposed approach, we conducted experiments on ECG dataset. The experimental results demonstrated the effectiveness of the proposed approach including promising performance and high efficiency, compared to conventional methods.

  4. Multi-Channel Distributed Coordinated Function over Single Radio in Wireless Sensor Networks

    PubMed Central

    Campbell, Carlene E.-A.; Loo, Kok-Keong (Jonathan); Gemikonakli, Orhan; Khan, Shafiullah; Singh, Dhananjay

    2011-01-01

    Multi-channel assignments are becoming the solution of choice to improve performance in single radio for wireless networks. Multi-channel allows wireless networks to assign different channels to different nodes in real-time transmission. In this paper, we propose a new approach, Multi-channel Distributed Coordinated Function (MC-DCF) which takes advantage of multi-channel assignment. The backoff algorithm of the IEEE 802.11 distributed coordination function (DCF) was modified to invoke channel switching, based on threshold criteria in order to improve the overall throughput for wireless sensor networks (WSNs) over 802.11 networks. We presented simulation experiments in order to investigate the characteristics of multi-channel communication in wireless sensor networks using an NS2 platform. Nodes only use a single radio and perform channel switching only after specified threshold is reached. Single radio can only work on one channel at any given time. All nodes initiate constant bit rate streams towards the receiving nodes. In this work, we studied the impact of non-overlapping channels in the 2.4 frequency band on: constant bit rate (CBR) streams, node density, source nodes sending data directly to sink and signal strength by varying distances between the sensor nodes and operating frequencies of the radios with different data rates. We showed that multi-channel enhancement using our proposed algorithm provides significant improvement in terms of throughput, packet delivery ratio and delay. This technique can be considered for WSNs future use in 802.11 networks especially when the IEEE 802.11n becomes popular thereby may prevent the 802.15.4 network from operating effectively in the 2.4 GHz frequency band. PMID:22346614

  5. Multi-channel distributed coordinated function over single radio in wireless sensor networks.

    PubMed

    Campbell, Carlene E-A; Loo, Kok-Keong Jonathan; Gemikonakli, Orhan; Khan, Shafiullah; Singh, Dhananjay

    2011-01-01

    Multi-channel assignments are becoming the solution of choice to improve performance in single radio for wireless networks. Multi-channel allows wireless networks to assign different channels to different nodes in real-time transmission. In this paper, we propose a new approach, Multi-channel Distributed Coordinated Function (MC-DCF) which takes advantage of multi-channel assignment. The backoff algorithm of the IEEE 802.11 distributed coordination function (DCF) was modified to invoke channel switching, based on threshold criteria in order to improve the overall throughput for wireless sensor networks (WSNs) over 802.11 networks. We presented simulation experiments in order to investigate the characteristics of multi-channel communication in wireless sensor networks using an NS2 platform. Nodes only use a single radio and perform channel switching only after specified threshold is reached. Single radio can only work on one channel at any given time. All nodes initiate constant bit rate streams towards the receiving nodes. In this work, we studied the impact of non-overlapping channels in the 2.4 frequency band on: constant bit rate (CBR) streams, node density, source nodes sending data directly to sink and signal strength by varying distances between the sensor nodes and operating frequencies of the radios with different data rates. We showed that multi-channel enhancement using our proposed algorithm provides significant improvement in terms of throughput, packet delivery ratio and delay. This technique can be considered for WSNs future use in 802.11 networks especially when the IEEE 802.11n becomes popular thereby may prevent the 802.15.4 network from operating effectively in the 2.4 GHz frequency band.

  6. Pulse-width tunable multi-channel NRZ-to-RZ conversion with duplicate output

    NASA Astrophysics Data System (ADS)

    Yu, Yu; Zhang, Xinliang; Huang, Dexiu

    2012-01-01

    We demonstrate multi-channel non-return-to-zero (NRZ) to return-to-zero (RZ) conversions with tunable output pulse-width and single-to-dual function, using a phase modulator and an array waveguide grating (AWG), which acts both detuned multi-channel filter and demultiplexer. Four-channel NRZ signals after transmission can be converted to eight-channel RZ signals with timing jitter and extinction ratio improvement. Further transmission and bit error ratio (BER) measurements for the converted RZ signal show a good performance compared with conventional one.

  7. NHS Direct Online: a multi-channel eHealth service.

    PubMed

    Gann, Bob

    2004-01-01

    In the UK NHS Direct has developed a multi-channel e-health service for patients and the public. NHS Direct is enabling patient and citizen opportunities for fast access to information by using 24 hour telephone call centres, the web, digital interactive tv and public touch screen kiosks. This multi-channel strategy is based on the principle of providing people with maximum choice in the route by which they access information, with the assurance of consistent high quality information whichever channel they choose.

  8. TTS-3, multi-channel, multi-system GPS/GLONAS/WAAS/EGNOS receiver

    NASA Astrophysics Data System (ADS)

    Nawrocki, J.; Nogas, P.; Diak, R.; Foks, A.; Lemanski, D.

    2006-10-01

    The Astrogeodynamic Observatory (AOS) of the Space Research Centre, following a popular TTS-2, has developed a new high-performance Time Transfer System - 3 (TTS-3). The TTS-3 allows observations of GPS, GLONASS, EGNOS andWAAS satellites simultaneously in multi-channel, multi-frequency mode. The following codes are used: C/A-code for GPS, WAAS, EGNOS and GLONASS, P-code for GLONASS, and reconstructed P-code for GPS. In future the receiver will be a base for a new generation TTS-4, observing also GALILEO satellites. The receiver hardware, the treatment of the observations, and the output data fulfill the recommendations of the CCTF Group on GNSS Time Transfer Standards (CGGTTS). Data in RINEX format are also provided.

  9. Designing Multi-Channel Web Frameworks for Cultural Tourism Applications: The MUSE Case Study.

    ERIC Educational Resources Information Center

    Garzotto, Franca; Salmon, Tullio; Pigozzi, Massimiliano

    A framework for the design of multi-channel (MC) applications in the cultural tourism domain is presented. Several heterogeneous interface devices are supported including location-sensitive mobile units, on-site stationary devices, and personalized CDs that extend the on-site experience beyond the visit time thanks to personal memories gathered…

  10. Spatial filter and feature selection optimization based on EA for multi-channel EEG.

    PubMed

    Wang, Yubo; Mohanarangam, Krithikaa; Mallipeddi, Rammohan; Veluvolu, K C

    2015-01-01

    The EEG signals employed for BCI systems are generally band-limited. The band-limited multiple Fourier linear combiner (BMFLC) with Kalman filter was developed to obtain amplitude estimates of the EEG signal in a pre-fixed frequency band in real-time. However, the high-dimensionality of the feature vector caused by the application of BMFLC to multi-channel EEG based BCI deteriorates the performance of the classifier. In this work, we apply evolutionary algorithm (EA) to tackle this problem. The real-valued EA encodes both the spatial filter and the feature selection into its solution and optimizes it with respect to the classification error. Three BMFLC based BCI configurations are proposed. Our results show that the BMFLC-KF with covariance matrix adaptation evolution strategy (CMAES) has the best overall performance.

  11. Multi-channel front-end board for SiPM readout

    NASA Astrophysics Data System (ADS)

    Auger, M.; Ereditato, A.; Goeldi, D.; Kreslo, I.; Lorca, D.; Luethi, M.; von Rohr, C. Rudolf; Sinclair, J.; Weber, M. S.

    2016-10-01

    We describe a novel high-speed front-end electronic board (FEB) for interfacing an array of 32 Silicon Photo-multipliers (SiPM) with a computer. The FEB provides individually adjustable bias for the SiPMs, and performs low-noise analog signal amplification, conditioning and digitization. It provides event timing information accurate to 1.3 ns RMS. The signal-to-noise ratio of 12 is attained for the first photo-electron peak. The back-end data interface is realized on the basis of 100 Mbps Ethernet. The design allows daisy-chaining of up to 256 units into one network interface, thus enabling compact and efficient readout schemes for multi-channel scintillating detectors, using SiPMs as photo-sensors.

  12. Multi-Channel Capacitive Sensor Arrays.

    PubMed

    Wang, Bingnan; Long, Jiang; Teo, Koon Hoo

    2016-01-25

    In this paper, multi-channel capacitive sensor arrays based on microstrip band-stop filters are studied. The sensor arrays can be used to detect the proximity of objects at different positions and directions. Each capacitive sensing structure in the array is connected to an inductive element to form resonance at different frequencies. The resonances are designed to be isolated in the frequency spectrum, such that the change in one channel does not affect resonances at other channels. The inductive element associated with each capacitive sensor can be surface-mounted inductors, integrated microstrip inductors or metamaterial-inspired structures. We show that by using metamaterial split-ring structures coupled to a microstrip line, the quality factor of each resonance can be greatly improved compared to conventional surface-mounted or microstrip meander inductors. With such a microstrip-coupled split-ring design, more sensing elements can be integrated in the same frequency spectrum, and the sensitivity can be greatly improved.

  13. Multi-Channel Capacitive Sensor Arrays

    PubMed Central

    Wang, Bingnan; Long, Jiang; Teo, Koon Hoo

    2016-01-01

    In this paper, multi-channel capacitive sensor arrays based on microstrip band-stop filters are studied. The sensor arrays can be used to detect the proximity of objects at different positions and directions. Each capacitive sensing structure in the array is connected to an inductive element to form resonance at different frequencies. The resonances are designed to be isolated in the frequency spectrum, such that the change in one channel does not affect resonances at other channels. The inductive element associated with each capacitive sensor can be surface-mounted inductors, integrated microstrip inductors or metamaterial-inspired structures. We show that by using metamaterial split-ring structures coupled to a microstrip line, the quality factor of each resonance can be greatly improved compared to conventional surface-mounted or microstrip meander inductors. With such a microstrip-coupled split-ring design, more sensing elements can be integrated in the same frequency spectrum, and the sensitivity can be greatly improved. PMID:26821023

  14. From complex B(1) mapping to local SAR estimation for human brain MR imaging using multi-channel transceiver coil at 7T.

    PubMed

    Zhang, Xiaotong; Schmitter, Sebastian; Van de Moortele, Pierre-Francois; Liu, Jiaen; He, Bin

    2013-06-01

    Elevated specific absorption rate (SAR) associated with increased main magnetic field strength remains a major safety concern in ultra-high-field (UHF) magnetic resonance imaging (MRI) applications. The calculation of local SAR requires the knowledge of the electric field induced by radio-frequency (RF) excitation, and the local electrical properties of tissues. Since electric field distribution cannot be directly mapped in conventional MR measurements, SAR estimation is usually performed using numerical model-based electromagnetic simulations which, however, are highly time consuming and cannot account for the specific anatomy and tissue properties of the subject undergoing a scan. In the present study, starting from the measurable RF magnetic fields (B1) in MRI, we conducted a series of mathematical deduction to estimate the local, voxel-wise and subject-specific SAR for each single coil element using a multi-channel transceiver array coil. We first evaluated the feasibility of this approach in numerical simulations including two different human head models. We further conducted experimental study in a physical phantom and in two human subjects at 7T using a multi-channel transceiver head coil. Accuracy of the results is discussed in the context of predicting local SAR in the human brain at UHF MRI using multi-channel RF transmission.

  15. From Complex B1 Mapping to Local SAR Estimation for Human Brain MR Imaging Using Multi-channel Transceiver Coil at 7T

    PubMed Central

    Zhang, Xiaotong; Schmitter, Sebastian; Van de Moortel, Pierre-François; Liu, Jiaen

    2014-01-01

    Elevated Specific Absorption Rate (SAR) associated with increased main magnetic field strength remains as a major safety concern in ultra-high-field (UHF) Magnetic Resonance Imaging (MRI) applications. The calculation of local SAR requires the knowledge of the electric field induced by radiofrequency (RF) excitation, and the local electrical properties of tissues. Since electric field distribution cannot be directly mapped in conventional MR measurements, SAR estimation is usually performed using numerical model-based electromagnetic simulations which, however, are highly time consuming and cannot account for the specific anatomy and tissue properties of the subject undergoing a scan. In the present study, starting from the measurable RF magnetic fields (B1) in MRI, we conducted a series of mathematical deduction to estimate the local, voxel-wise and subject-specific SAR for each single coil element using a multi-channel transceiver array coil. We first evaluated the feasibility of this approach in numerical simulations including two different human head models. We further conducted experimental study in a physical phantom and in two human subjects at 7T using a multi-channel transceiver head coil. Accuracy of the results is discussed in the context of predicting local SAR in the human brain at UHF MRI using multi-channel RF transmission. PMID:23508259

  16. High resolution time interval counter

    NASA Technical Reports Server (NTRS)

    Zhang, Victor S.; Davis, Dick D.; Lombardi, Michael A.

    1995-01-01

    In recent years, we have developed two types of high resolution, multi-channel time interval counters. In the NIST two-way time transfer MODEM application, the counter is designed for operating primarily in the interrupt-driven mode, with 3 start channels and 3 stop channels. The intended start and stop signals are 1 PPS, although other frequencies can also be applied to start and stop the count. The time interval counters used in the NIST Frequency Measurement and Analysis System are implemented with 7 start channels and 7 stop channels. Four of the 7 start channels are devoted to the frequencies of 1 MHz, 5 MHz or 10 MHz, while triggering signals to all other start and stop channels can range from 1 PPS to 100 kHz. Time interval interpolation plays a key role in achieving the high resolution time interval measurements for both counters. With a 10 MHz time base, both counters demonstrate a single-shot resolution of better than 40 ps, and a stability of better than 5 x 10(exp -12) (sigma(sub chi)(tau)) after self test of 1000 seconds). The maximum rate of time interval measurements (with no dead time) is 1.0 kHz for the counter used in the MODEM application and is 2.0 kHz for the counter used in the Frequency Measurement and Analysis System. The counters are implemented as plug-in units for an AT-compatible personal computer. This configuration provides an efficient way of using a computer not only to control and operate the counters, but also to store and process measured data.

  17. Harnessing mode-selective nonlinear optics for on-chip multi-channel all-optical signal processing

    NASA Astrophysics Data System (ADS)

    Ma, Ming; Chen, Lawrence R.

    2016-11-01

    All-optical signal processing based on nonlinear optical effects allows for the realization of important functions in telecommunications including wavelength conversion, optical multiplexing/demultiplexing, Fourier transformation, and regeneration, amongst others, on ultrafast time scales to support high data rate transmission. In integrated photonic subsystems, the majority of all-optical signal processing systems demonstrated to date typically process only a single channel at a time or perform a single processing function, which imposes a serious limitation on the functionality of integrated solutions. Here, we demonstrate how nonlinear optical effects can be harnessed in a mode-selective manner to perform simultaneous multi-channel (two) and multi-functional optical signal processing (i.e., regenerative wavelength conversion) in an integrated silicon photonic device. This approach, which can be scaled to a higher number of channels, opens up a new degree of freedom for performing a broad range of multi-channel nonlinear optical signal processing functions using a single integrated photonic device.

  18. Towards a multi-channel TOF-PET system with SiPM readout

    NASA Astrophysics Data System (ADS)

    Garutti, Erika; Göttlich, Martin; Harion, Tobias; Hegemann, Niklas; Schmidt, Maximilian; Schultz-Coulon, Hans-Christian; Shen, Wei; Silenzi, Alessandro; Stamen, Rainer; Tadday, Alexander; Xu, Chen

    2012-12-01

    The goal of this project is to develop a multi-channel TOF-PET system with a 300 ps FWHM time resolution, a factor two improvement with respect to commercially available systems (Surti et al., 2007 [1]). In a TOF-PET system, the time-of-flight information can be used to improve significantly the sensitivity of the detector as shown in Karp et al. (2008) [2]. The target time resolution has been achieved in two channel systems with LYSO (Kim and Wang, 2008 [3]), the aim is to port this results into a multi-channel system. This work extends the results shown in Göttlich et al. (2010) [4], studying the stability of the detector performance in different geometries and configurations.

  19. Spectrally Shaped DP-16QAM Super-Channel Transmission with Multi-Channel Digital Back-Propagation

    NASA Astrophysics Data System (ADS)

    Maher, Robert; Xu, Tianhua; Galdino, Lidia; Sato, Masaki; Alvarado, Alex; Shi, Kai; Savory, Seb J.; Thomsen, Benn C.; Killey, Robert I.; Bayvel, Polina

    2015-02-01

    The achievable transmission capacity of conventional optical fibre communication systems is limited by nonlinear distortions due to the Kerr effect and the difficulty in modulating the optical field to effectively use the available fibre bandwidth. In order to achieve a high information spectral density (ISD), while simultaneously maintaining transmission reach, multi-channel fibre nonlinearity compensation and spectrally efficient data encoding must be utilised. In this work, we use a single coherent super-receiver to simultaneously receive a DP-16QAM super-channel, consisting of seven spectrally shaped 10GBd sub-carriers spaced at the Nyquist frequency. Effective nonlinearity mitigation is achieved using multi-channel digital back-propagation (MC-DBP) and this technique is combined with an optimised forward error correction implementation to demonstrate a record gain in transmission reach of 85%; increasing the maximum transmission distance from 3190 km to 5890 km, with an ISD of 6.60 b/s/Hz. In addition, this report outlines for the first time, the sensitivity of MC-DBP gain to linear transmission line impairments and defines a trade-off between performance and complexity.

  20. Spectrally Shaped DP-16QAM Super-Channel Transmission with Multi-Channel Digital Back-Propagation

    PubMed Central

    Maher, Robert; Xu, Tianhua; Galdino, Lidia; Sato, Masaki; Alvarado, Alex; Shi, Kai; Savory, Seb J.; Thomsen, Benn C.; Killey, Robert I.; Bayvel, Polina

    2015-01-01

    The achievable transmission capacity of conventional optical fibre communication systems is limited by nonlinear distortions due to the Kerr effect and the difficulty in modulating the optical field to effectively use the available fibre bandwidth. In order to achieve a high information spectral density (ISD), while simultaneously maintaining transmission reach, multi-channel fibre nonlinearity compensation and spectrally efficient data encoding must be utilised. In this work, we use a single coherent super-receiver to simultaneously receive a DP-16QAM super-channel, consisting of seven spectrally shaped 10GBd sub-carriers spaced at the Nyquist frequency. Effective nonlinearity mitigation is achieved using multi-channel digital back-propagation (MC-DBP) and this technique is combined with an optimised forward error correction implementation to demonstrate a record gain in transmission reach of 85%; increasing the maximum transmission distance from 3190 km to 5890 km, with an ISD of 6.60 b/s/Hz. In addition, this report outlines for the first time, the sensitivity of MC-DBP gain to linear transmission line impairments and defines a trade-off between performance and complexity. PMID:25645457

  1. Multiple-animal MR imaging using a 3T clinical scanner and multi-channel coil for volumetric analysis in a mouse tumor model.

    PubMed

    Mitsuda, Minoru; Yamaguchi, Masayuki; Furuta, Toshihiro; Nabetani, Akira; Hirayama, Akira; Nozaki, Atsushi; Niitsu, Mamoru; Fujii, Hirofumi

    2011-01-01

    Multiple small-animal magnetic resonance (MR) imaging to measure tumor volume may increase the throughput of preclinical cancer research assessing tumor response to novel therapies. We used a clinical scanner and multi-channel coil to evaluate the usefulness of this imaging to assess experimental tumor volume in mice. We performed a phantom study to assess 2-dimensional (2D) geometric distortion using 9-cm spherical and 32-cell (8×4 one-cm(2) grids) phantoms using a 3-tesla clinical MR scanner and dedicated multi-channel coil composed of 16 5-cm circular coils. Employing the multi-channel coil, we simultaneously scanned 6 or 8 mice bearing sarcoma 180 tumors. We estimated tumor volume from the sum of the product of tumor area and slice thickness on 2D spin-echo images (repetition time/echo time, 3500/16 ms; in-plane resolution, 0.195×0.195×1 mm(3)). After MR acquisition, we excised and weighed tumors, calculated reference tumor volumes from actual tumor weight assuming a density of 1.05 g/cm(3), and assessed the correlation between the estimated and reference volumes using Pearson's test. Two-dimensional geometric distortion was acceptable below 5% in the 9-cm spherical phantom and in every cell in the 32-cell phantom. We scanned up to 8 mice simultaneously using the multi-channel coil and found 11 tumors larger than 0.1 g in 12 mice. Tumor volumes were 1.04±0.73 estimated by MR imaging and 1.04±0.80 cm(3) by reference volume (average±standard deviation) and highly correlated (correlation coefficient, 0.995; P<0.01, Pearson's test). Use of multiple small-animal MR imaging employing a clinical scanner and multi-channel coil enabled accurate assessment of experimental tumor volume in a large number of mice and may facilitate high throughput monitoring of tumor response to therapy in preclinical research.

  2. FPGA-based multi-channel fluorescence lifetime analysis of Fourier multiplexed frequency-sweeping lifetime imaging

    PubMed Central

    Zhao, Ming; Li, Yu; Peng, Leilei

    2014-01-01

    We report a fast non-iterative lifetime data analysis method for the Fourier multiplexed frequency-sweeping confocal FLIM (Fm-FLIM) system [ Opt. Express22, 10221 ( 2014)24921725]. The new method, named R-method, allows fast multi-channel lifetime image analysis in the system’s FPGA data processing board. Experimental tests proved that the performance of the R-method is equivalent to that of single-exponential iterative fitting, and its sensitivity is well suited for time-lapse FLIM-FRET imaging of live cells, for example cyclic adenosine monophosphate (cAMP) level imaging with GFP-Epac-mCherry sensors. With the R-method and its FPGA implementation, multi-channel lifetime images can now be generated in real time on the multi-channel frequency-sweeping FLIM system, and live readout of FRET sensors can be performed during time-lapse imaging. PMID:25321778

  3. FPGA-based multi-channel fluorescence lifetime analysis of Fourier multiplexed frequency-sweeping lifetime imaging.

    PubMed

    Zhao, Ming; Li, Yu; Peng, Leilei

    2014-09-22

    We report a fast non-iterative lifetime data analysis method for the Fourier multiplexed frequency-sweeping confocal FLIM (Fm-FLIM) system [Opt. Express 22, 10221 (2014)]. The new method, named R-method, allows fast multi-channel lifetime image analysis in the system's FPGA data processing board. Experimental tests proved that the performance of the R-method is equivalent to that of single-exponential iterative fitting, and its sensitivity is well suited for time-lapse FLIM-FRET imaging of live cells, for example cyclic adenosine monophosphate (cAMP) level imaging with GFP-Epac-mCherry sensors. With the R-method and its FPGA implementation, multi-channel lifetime images can now be generated in real time on the multi-channel frequency-sweeping FLIM system, and live readout of FRET sensors can be performed during time-lapse imaging.

  4. Photon counting with photon number resolution through superconducting nanowires coupled to a multi-channel TDC in FPGA

    NASA Astrophysics Data System (ADS)

    Lusardi, N.; Los, J. W. N.; Gourgues, R. B. M.; Bulgarini, G.; Geraci, A.

    2017-03-01

    The paper presents a system for measuring photon statistics and photon timing in the few-photon regime down to the single-photon level. The measurement system is based on superconducting nanowire single photon detectors and a time-to-digital converter implemented into a programmable device. The combination of these devices gives high performance to the system in terms of resolution and adaptability to the actual experimental conditions. As a case of application, we present the measurement of photon statistics for coherent light states. In this measurement, we make use of 8th order single photon correlations to reconstruct with high fidelity the statistics of a coherent state with average photon number up to 4. The processing is performed by means of a tapped-delay-line time-to-digital converter architecture that also hosts an asynchronous-correlated-digital-counter implemented in a field programmable gate array device and specifically designed for performance optimization in multi-channel usage.

  5. Photon counting with photon number resolution through superconducting nanowires coupled to a multi-channel TDC in FPGA.

    PubMed

    Lusardi, N; Los, J W N; Gourgues, R B M; Bulgarini, G; Geraci, A

    2017-03-01

    The paper presents a system for measuring photon statistics and photon timing in the few-photon regime down to the single-photon level. The measurement system is based on superconducting nanowire single photon detectors and a time-to-digital converter implemented into a programmable device. The combination of these devices gives high performance to the system in terms of resolution and adaptability to the actual experimental conditions. As a case of application, we present the measurement of photon statistics for coherent light states. In this measurement, we make use of 8th order single photon correlations to reconstruct with high fidelity the statistics of a coherent state with average photon number up to 4. The processing is performed by means of a tapped-delay-line time-to-digital converter architecture that also hosts an asynchronous-correlated-digital-counter implemented in a field programmable gate array device and specifically designed for performance optimization in multi-channel usage.

  6. Dynamic multi-channel TMS with reconfigurable coil.

    PubMed

    Jiang, Ruoli; Jansen, Ben H; Sheth, Bhavin R; Chen, Ji

    2013-05-01

    Investigations of the causal involvement of particular brain areas and interconnections in behavior require an external stimulation system with reasonable spatio-temporal resolution. Current transcranial magnetic stimulation (TMS) technology is limited to stimulating a single brain area once in a given trial. Here, we present a feasibility study for a novel TMS system based on multi-channel reconfigurable coils. With this hardware, researchers will be able to stimulate multiple brain sites in any temporal order in a trial. The system employs a wire-mesh coil, constructed using x- and y-directional wires. By varying the current direction and/or strength on each wire, we can configure the proposed mesh-wire coil into a standard loop coil and figure-eight coil of varying size. This provides maximum flexibility to the experimenter in that the location and extent of stimulation on the brain surface can be modified depending on experimental requirement. Moreover, one can dynamically and automatically modify the site(s) of stimulation several times within the span of seconds. By pre-storing various sequences of excitation patterns inside a control unit, one can explore the effect of dynamic TMS on behavior, in associative learning, and as rehabilitative therapy. Here, we present a computer simulation and bench experiments that show the feasibility of the dynamically-reconfigurable coil.

  7. Quasiclassical theory of disordered multi-channel Majorana quantum wires

    NASA Astrophysics Data System (ADS)

    Neven, Patrick; Bagrets, Dmitry; Altland, Alexander

    2013-05-01

    Multi-channel spin-orbit quantum wires, when subjected to a magnetic field and proximity coupled to an s-wave superconductor, may support Majorana states. We study what happens to these systems in the presence of disorder. Inspired by the widely established theoretical methods of mesoscopic superconductivity, we develop á la Eilenberger a quasiclassical approach to topological nanowires valid in the limit of strong spin-orbit coupling. We find that the ‘Majorana number’ {\\cal M} , distinguishing between the state with Majorana fermions (symmetry class B) and no Majorana fermions (class D), is given by the product of two Pfaffians of gapped quasiclassical Green's functions fixed by the right and left terminals connected to the wire. A numerical solution of the Eilenberger equations reveals that the class D disordered quantum wires are prone to the formation of the zero-energy anomaly (class D impurity spectral peak) in the local density of states that shares the key features of the Majorana peak. In this way, we confirm the robustness of our previous conclusions (Bagrets and Altland 2012 Phys. Rev. Lett. 109 227005) on a more restrictive system setup. Generally speaking, we find that the quasiclassical approach provides a highly efficient means to address disordered class D superconductors both in the presence and in the absence of topological structures.

  8. Multi-Channel Transfer Function with Dimensionality Reduction

    PubMed Central

    Kim, Han Suk; Schulze, Jürgen P.; Cone, Angela C.; Sosinsky, Gina E.; Martone, Maryann E.

    2010-01-01

    The design of transfer functions for volume rendering is a difficult task. This is particularly true for multi-channel data sets, where multiple data values exist for each voxel. In this paper, we propose a new method for transfer function design. Our new method provides a framework to combine multiple approaches and pushes the boundary of gradient-based transfer functions to multiple channels, while still keeping the dimensionality of transfer functions to a manageable level, i.e., a maximum of three dimensions, which can be displayed visually in a straightforward way. Our approach utilizes channel intensity, gradient, curvature and texture properties of each voxel. The high-dimensional data of the domain is reduced by applying recently developed nonlinear dimensionality reduction algorithms. In this paper, we used Isomap as well as a traditional algorithm, Principle Component Analysis (PCA). Our results show that these dimensionality reduction algorithms significantly improve the transfer function design process without compromising visualization accuracy. In this publication we report on the impact of the dimensionality reduction algorithms on transfer function design for confocal microscopy data. PMID:20582228

  9. Adaptive spatio-temporal filtering of disturbed ECGs: a multi-channel approach to heartbeat detection in smart clothing.

    PubMed

    Wiklund, Urban; Karlsson, Marcus; Ostlund, Nils; Berglin, Lena; Lindecrantz, Kaj; Karlsson, Stefan; Sandsjö, Leif

    2007-06-01

    Intermittent disturbances are common in ECG signals recorded with smart clothing: this is mainly because of displacement of the electrodes over the skin. We evaluated a novel adaptive method for spatio-temporal filtering for heartbeat detection in noisy multi-channel ECGs including short signal interruptions in single channels. Using multi-channel database recordings (12-channel ECGs from 10 healthy subjects), the results showed that multi-channel spatio-temporal filtering outperformed regular independent component analysis. We also recorded seven channels of ECG using a T-shirt with textile electrodes. Ten healthy subjects performed different sequences during a 10-min recording: resting, standing, flexing breast muscles, walking and pushups. Using adaptive multi-channel filtering, the sensitivity and precision was above 97% in nine subjects. Adaptive multi-channel spatio-temporal filtering can be used to detect heartbeats in ECGs with high noise levels. One application is heartbeat detection in noisy ECG recordings obtained by integrated textile electrodes in smart clothing.

  10. Multimodal medical image fusion using improved multi-channel PCNN.

    PubMed

    Zhao, Yaqian; Zhao, Qinping; Hao, Aimin

    2014-01-01

    Multimodal medical image fusion is a method of integrating information from multiple image formats. Its aim is to provide useful and accurate information for doctors. Multi-channel pulse coupled neural network (m-PCNN) is a recently proposed fusion model. Compared with previous methods, this network can effectively manage various types of medical images. However, it has two drawbacks: lack of control to feed function and low-level automation. The improved multi-channel PCNN proposed in this paper can adjust the impact of feed function by linking strength and adaptively compute the weighting coefficients for each pixel. Experimental results demonstrated the effectiveness of the improved m-PCNN fusion model.

  11. Multi channel FM reflection profiler for buried pipeline surveying

    SciTech Connect

    Schock, S.G.; LeBlanc, L.R.

    1996-12-31

    A towed multi-channel FM acoustic reflection profiler has been developed for locating and generating images of buried objects. One significant application of this sonar is buried pipeline surveying. The multi-channel reflection profiler uses 16 line arrays mounted in a towed vehicle to determine the position and burial depth of an 18 inch steel pipe filled with concrete buried under 1.5 meters of sand. This sonar will allow a survey vessel to continuously track a buried pipeline providing a continuous record of pipe burial depth and position.

  12. An Efficient VLSI Architecture for Multi-Channel Spike Sorting Using a Generalized Hebbian Algorithm

    PubMed Central

    Chen, Ying-Lun; Hwang, Wen-Jyi; Ke, Chi-En

    2015-01-01

    A novel VLSI architecture for multi-channel online spike sorting is presented in this paper. In the architecture, the spike detection is based on nonlinear energy operator (NEO), and the feature extraction is carried out by the generalized Hebbian algorithm (GHA). To lower the power consumption and area costs of the circuits, all of the channels share the same core for spike detection and feature extraction operations. Each channel has dedicated buffers for storing the detected spikes and the principal components of that channel. The proposed circuit also contains a clock gating system supplying the clock to only the buffers of channels currently using the computation core to further reduce the power consumption. The architecture has been implemented by an application-specific integrated circuit (ASIC) with 90-nm technology. Comparisons to the existing works show that the proposed architecture has lower power consumption and hardware area costs for real-time multi-channel spike detection and feature extraction. PMID:26287193

  13. An Efficient VLSI Architecture for Multi-Channel Spike Sorting Using a Generalized Hebbian Algorithm.

    PubMed

    Chen, Ying-Lun; Hwang, Wen-Jyi; Ke, Chi-En

    2015-08-13

    A novel VLSI architecture for multi-channel online spike sorting is presented in this paper. In the architecture, the spike detection is based on nonlinear energy operator (NEO), and the feature extraction is carried out by the generalized Hebbian algorithm (GHA). To lower the power consumption and area costs of the circuits, all of the channels share the same core for spike detection and feature extraction operations. Each channel has dedicated buffers for storing the detected spikes and the principal components of that channel. The proposed circuit also contains a clock gating system supplying the clock to only the buffers of channels currently using the computation core to further reduce the power consumption. The architecture has been implemented by an application-specific integrated circuit (ASIC) with 90-nm technology. Comparisons to the existing works show that the proposed architecture has lower power consumption and hardware area costs for real-time multi-channel spike detection and feature extraction.

  14. Method of synchronization measurement via spatial-spectral interference in coherent combination of multi-channel ultra-short pulses

    NASA Astrophysics Data System (ADS)

    Li, Z. L.; Zuo, Y. L.; Wu, Z. H.; Wang, X.; Mu, J.; Yu, H. Y.; Zhao, D.; Zhu, Q. H.; Su, J. Q.; Zhou, K. N.; Zhou, S.; Feng, X.; Zhang, S.; Liu, H. Z.

    2017-08-01

    Spatial-spectral interference fringes contain information on the time delay between pulses. By extracting the slope of the equiphase line in the spatial-spectral interference fringes, a large range and high-precision detection of the time delay is realized. Theoretical analysis is given. An experiment demonstrates the fundamental process for obtaining the time delay between two femtosecond pulses. In the current experiment the measurement range is from 0.4 fs to hundreds of fs. This method was first proposed for synchronization measurement of coherent combination of ultra-short pulses in a multi-channel system. The method can be applied at large scales in an ultra-short pulse laser facility.

  15. OCTOCAM: a fast multi-channel imager and spectrograph for the Gemini telescopes

    NASA Astrophysics Data System (ADS)

    de Ugarte Postigo, Antonio

    2015-08-01

    OCTOCAM has been proposed as a future instrument for Gemini and is currently going through a feasibility study phase. Its a multi-channel instrument based on the use of high-efficiency dichroics to divide the light into eight optical and near-infrared arms. In its imaging mode it has a field of view of 3’x3’ that is simultaneously observed in eight bands. It is also designed to obtain spectroscopy from 370 to 2,400 nm in a single shot, with a spectral resolution of ~3,000. OCTOCAM will be capable of obtaining full-Stokes spectropolarimetry to study geometry and magnetic fields of astrophysical phenomena. It will be equipped with a mini-IFU (Integral Field Unit) to perform resolved spectroscopic studies in an area of a few arcseconds. Furthermore, thanks to the use of state of the art detectors, it will be able to reach high readout speeds, allowing science cases aimed at high time-resolution. We expect full frame rate reaching speeds of tens of Hertz, which will be even higher for windowed modes. This will also mean that OCTOCAM will virtually eliminate dead times in most observing modes, allowing duty cycles of roughly 100%. In this way, OCTOCAM will cover a region of the (spectral-resolution)-(spectral-coverage)-(temporal-resolution) diagram that is not occupied by any other single instrument in the world.

  16. Single-channel and multi-channel orthogonal matching pursuit for seismic trace decomposition

    NASA Astrophysics Data System (ADS)

    Feng, Xuan; Zhang, Xuebing; Liu, Cai; Lu, Qi

    2017-02-01

    The conventional matching pursuit (MP) algorithm can decompose a 1D signal into a set of wavelet atoms adaptively. As to reflection seismic data, some applicable algorithms based on the MP decomposition has been developed, such as single-channel matching pursuit (SCMP) and multi-channel matching pursuit (MCMP). However, these algorithms cannot always select the optimal atoms, which results in less meaningful decompositions. To overcome this limitation, we introduce the idea of orthogonal matching pursuit into a multi-channel decomposition scheme, which we refer to as the multi-channel orthogonal matching pursuit (MCOMP). Each iteration of the proposed MCOMP might extract a more reasonable atom among a redundant Morlet wavelet dictionary, like the MCMP decomposition does, and estimate the corresponding amplitude more accurately by solving a least-squares problem. In order to correspond to SCMP, we also simplified the MCOMP decomposition to single-channel orthogonal matching pursuit (SCOMP) for decompositions of an individual seismic trace. We tested the proposed SCOMP algorithm on a synthetic signal and a field seismic trace. Then a field marine dataset example showed relative high resolution of the proposed MCOMP method with applications to the detection of low-frequency anomalies. These application examples all demonstrate more meaningful decomposition results and relative high convergence speed of the proposed algorithms.

  17. Multi-channel electronically scanned cryogenic pressure sensor

    NASA Technical Reports Server (NTRS)

    Chapman, John J. (Inventor); Hopson, Purnell, Jr. (Inventor); Kruse, Nancy M. H. (Inventor)

    1995-01-01

    A miniature, multi-channel, electronically scanned pressure measuring device uses electrostatically bonded silicon dies in a multielement array. These dies are bonded at specific sites on a glass, prepatterned substrate. Thermal data is multiplexed and recorded on each individual pressure measuring diaphragm. The device functions in a cryogenic environment without the need of heaters to keep the sensor at constant temperatures.

  18. A New, Scalable and Low Cost Multi-Channel Monitoring System for Polymer Electrolyte Fuel Cells

    PubMed Central

    Calderón, Antonio José; González, Isaías; Calderón, Manuel; Segura, Francisca; Andújar, José Manuel

    2016-01-01

    In this work a new, scalable and low cost multi-channel monitoring system for Polymer Electrolyte Fuel Cells (PEFCs) has been designed, constructed and experimentally validated. This developed monitoring system performs non-intrusive voltage measurement of each individual cell of a PEFC stack and it is scalable, in the sense that it is capable to carry out measurements in stacks from 1 to 120 cells (from watts to kilowatts). The developed system comprises two main subsystems: hardware devoted to data acquisition (DAQ) and software devoted to real-time monitoring. The DAQ subsystem is based on the low-cost open-source platform Arduino and the real-time monitoring subsystem has been developed using the high-level graphical language NI LabVIEW. Such integration can be considered a novelty in scientific literature for PEFC monitoring systems. An original amplifying and multiplexing board has been designed to increase the Arduino input port availability. Data storage and real-time monitoring have been performed with an easy-to-use interface. Graphical and numerical visualization allows a continuous tracking of cell voltage. Scalability, flexibility, easy-to-use, versatility and low cost are the main features of the proposed approach. The system is described and experimental results are presented. These results demonstrate its suitability to monitor the voltage in a PEFC at cell level. PMID:27005630

  19. A New, Scalable and Low Cost Multi-Channel Monitoring System for Polymer Electrolyte Fuel Cells.

    PubMed

    Calderón, Antonio José; González, Isaías; Calderón, Manuel; Segura, Francisca; Andújar, José Manuel

    2016-03-09

    In this work a new, scalable and low cost multi-channel monitoring system for Polymer Electrolyte Fuel Cells (PEFCs) has been designed, constructed and experimentally validated. This developed monitoring system performs non-intrusive voltage measurement of each individual cell of a PEFC stack and it is scalable, in the sense that it is capable to carry out measurements in stacks from 1 to 120 cells (from watts to kilowatts). The developed system comprises two main subsystems: hardware devoted to data acquisition (DAQ) and software devoted to real-time monitoring. The DAQ subsystem is based on the low-cost open-source platform Arduino and the real-time monitoring subsystem has been developed using the high-level graphical language NI LabVIEW. Such integration can be considered a novelty in scientific literature for PEFC monitoring systems. An original amplifying and multiplexing board has been designed to increase the Arduino input port availability. Data storage and real-time monitoring have been performed with an easy-to-use interface. Graphical and numerical visualization allows a continuous tracking of cell voltage. Scalability, flexibility, easy-to-use, versatility and low cost are the main features of the proposed approach. The system is described and experimental results are presented. These results demonstrate its suitability to monitor the voltage in a PEFC at cell level.

  20. Content-Based Multi-Channel Network Coding Algorithm in the Millimeter-Wave Sensor Network

    PubMed Central

    Lin, Kai; Wang, Di; Hu, Long

    2016-01-01

    With the development of wireless technology, the widespread use of 5G is already an irreversible trend, and millimeter-wave sensor networks are becoming more and more common. However, due to the high degree of complexity and bandwidth bottlenecks, the millimeter-wave sensor network still faces numerous problems. In this paper, we propose a novel content-based multi-channel network coding algorithm, which uses the functions of data fusion, multi-channel and network coding to improve the data transmission; the algorithm is referred to as content-based multi-channel network coding (CMNC). The CMNC algorithm provides a fusion-driven model based on the Dempster-Shafer (D-S) evidence theory to classify the sensor nodes into different classes according to the data content. By using the result of the classification, the CMNC algorithm also provides the channel assignment strategy and uses network coding to further improve the quality of data transmission in the millimeter-wave sensor network. Extensive simulations are carried out and compared to other methods. Our simulation results show that the proposed CMNC algorithm can effectively improve the quality of data transmission and has better performance than the compared methods. PMID:27376302

  1. Multi-channel intracavitary vaginal brachytherapy using three-dimensional optimization of source geometry.

    PubMed

    Tanderup, Kari; Lindegaard, Jacob C

    2004-01-01

    A new multi-channel vaginal cylinder has been constructed. The dose distribution is compared to that of a central channel cylinder. The source channels of the multi-channel cylinder are placed close to the treatment volume, which means that the dose gradient in the radial direction is steep. Therefore the dose is enhanced close to the cylinder surface and lowered at larger distances as compared to the central channel cylinder. Three patients were each CT-scanned twice with a vaginal cylinder in situ. CT-based 3D dose-planning studies were used to calculate the dose distribution. Dose-volume histograms (DVHs) were generated for rectum and bladder, and a quantification of high dose volumes was calculated from the DVHs. Dose to the vaginal mucosa was calculated. The dose to the critical organs depends on the depth of normalization. When the dose is normalized on the cylinder surface the hot spot dose to bladder and rectum is reduced by 16 and 17%, respectively, whereas mucosal dose remains the same. When the dose is normalized at 5 mm depth the hot spot dose to bladder and rectum is reduced by 1 and 3%, respectively, whereas mucosal dose is enhanced by 17%. The multi-channel cylinder makes it possible to spare the rectum and the bladder at the expense of enhanced mucosal dose.

  2. Content-Based Multi-Channel Network Coding Algorithm in the Millimeter-Wave Sensor Network.

    PubMed

    Lin, Kai; Wang, Di; Hu, Long

    2016-07-01

    With the development of wireless technology, the widespread use of 5G is already an irreversible trend, and millimeter-wave sensor networks are becoming more and more common. However, due to the high degree of complexity and bandwidth bottlenecks, the millimeter-wave sensor network still faces numerous problems. In this paper, we propose a novel content-based multi-channel network coding algorithm, which uses the functions of data fusion, multi-channel and network coding to improve the data transmission; the algorithm is referred to as content-based multi-channel network coding (CMNC). The CMNC algorithm provides a fusion-driven model based on the Dempster-Shafer (D-S) evidence theory to classify the sensor nodes into different classes according to the data content. By using the result of the classification, the CMNC algorithm also provides the channel assignment strategy and uses network coding to further improve the quality of data transmission in the millimeter-wave sensor network. Extensive simulations are carried out and compared to other methods. Our simulation results show that the proposed CMNC algorithm can effectively improve the quality of data transmission and has better performance than the compared methods.

  3. A compact multi-channel fluorescence sensor with ambient light suppression

    NASA Astrophysics Data System (ADS)

    Egly, Dominik; Geörg, Daniel; Rädle, Matthias; Beuermann, Thomas

    2012-03-01

    A multi-channel fluorescence sensor has been developed for process monitoring and fluorescence diagnostics. It comprises a fiber-optic set-up with an immersion probe and an intensity-modulated high power ultraviolet light-emitting diode as a light source for fluorescence excitation. By applying an electronic lock-in procedure, fluorescence signals are selectively detectable at ambient light levels of 1000 000 times higher intensity. The sensor was designed to be compact, low cost and easily adaptable to a wide field of application. The set-up was used to simultaneously monitor three important metabolic fluorophores: NAD(P)H, flavins and porphyrins during the cultivation of a baker's yeast. Moreover, the accumulation and degradation kinetics of protoporphyrin IX induced by 5-aminolevulinic acid on the skin could be recorded by the sensor. The detection limit for protoporphyrin IX was determined to be 4 × 10-11 mol L-1. The linear signal amplification of the sensor and time courses of fluorescence signals monitored during yeast fermentations were validated using a commercial CCD spectrometer. The robust and flexible set-up of the fiber-optic measurement system promises easy implementation of this non-invasive analytical tool to fluorescence monitoring and diagnostics in R&D and production.

  4. Enabling Technology for the Exploration of the Arctic Ocean - Multi Channel Seismic Reflection data acquisition

    NASA Astrophysics Data System (ADS)

    Coakley, B.; Anderson, R.; Chayes, D. N.; Goemmer, S.; Oursler, M.

    2009-12-01

    Great advances in mapping the Arctic Ocean have recently been made through the relatively routine acquisition of multibeam data from icebreakers operating on various cruise. The USCGC Healy, the German icebreaker Polarstern, the Canadian icebreaker Amundsen and the Swedish icebreaker Oden all routinely collect multibeam data, even while in heavy ice pack. This increase in data has substantially improved our knowledge of the form of the Arctic Ocean seafloor. Unfortunately, it is not possible to routinely collect Multi Channel Seismic Reflection (MCS) data while underway in the ice pack. Our inability to simply collect these data restricts how we understand many of the features that segment the basin by depriving us of the historical information that can be obtained by imaging the stratigraphy. Without these data, scientific ocean drilling, the ultimate ground truth for Marine Geology, cannot be done. The technology and expertise to collect MCS must be adapted for the particular circumstances of the Arctic Ocean. While MCS data have been collected in the Arctic Ocean, the procedures have relied on icebreakers towing equipment. Since icebreakers follow the path of least resistance through the pack, data are acquired in locations that are not scientifically optimal and rarely in the relatively straight lines necessary for optimal processing. Towing in the ice pack is also difficult, inefficient and puts this equipment at substantial risk of crushing or loss. While icebreakers are one means to collect these data, it is time to conduct a systematic evaluation of the costs and benefits of different platforms for MCS data acquisition. This evaluation should enable collection of high-quality data set at selected locations to solve scientific problems. Substantial uncertainties exist about the relative capabilities, costs and limitations for acquisition of MCS data from various platforms in the Arctic Ocean. For example; - Is it possible to collect multi-channel seismic

  5. Multi-channel photon migration study in visible Chinese human muscle for optical detection of deep vein thrombosis

    NASA Astrophysics Data System (ADS)

    Sun, Yunlong; Li, Ting

    2016-03-01

    Deep vein thrombosis (DVT) always induced venous thrombosis. Most cases of venous thrombosis were induced by deep vein thrombosis (DVT), with high incidence rate of >60% in >60 years old people. Near-infrared spectroscopy (NIRS) were reported recently to be an intriguing and potential technique in detecting DVT in clinics. However, the photon transport is still unclear, which is crucial for the image reconstruction of the updated development called as NIRS-based DVT imager. Here we employed the Monte Carlo simulation software for 3D voxelized media (MCVM) and the Visible Chinese Human (VCH) model, which segmentation is finest in the world, to simulate multi-channel photon migration in calf muscle. And the image reconstruction of DVT hemodynamic distribution was achieved. This study, for the first time, provides the most realistic 3-D multichannel photon migration for NIRS study on DVT, and explored the image reconstruction for furtherly developing a NIRS-based DVT imager.

  6. Retrieving Land Surface Temperature from Hyperspectral Thermal Infrared Data Using a Multi-Channel Method

    PubMed Central

    Zhong, Xinke; Huo, Xing; Ren, Chao; Labed, Jelila; Li, Zhao-Liang

    2016-01-01

    Land Surface Temperature (LST) is a key parameter in climate systems. The methods for retrieving LST from hyperspectral thermal infrared data either require accurate atmospheric profile data or require thousands of continuous channels. We aim to retrieve LST for natural land surfaces from hyperspectral thermal infrared data using an adapted multi-channel method taking Land Surface Emissivity (LSE) properly into consideration. In the adapted method, LST can be retrieved by a linear function of 36 brightness temperatures at Top of Atmosphere (TOA) using channels where LSE has high values. We evaluated the adapted method using simulation data at nadir and satellite data near nadir. The Root Mean Square Error (RMSE) of the LST retrieved from the simulation data is 0.90 K. Compared with an LST product from the Spinning Enhanced Visible and Infrared Imager (SEVIRI) on Meteosat, the error in the LST retrieved from the Infared Atmospheric Sounding Interferometer (IASI) is approximately 1.6 K. The adapted method can be used for the near-real-time production of an LST product and to provide the physical method to simultaneously retrieve atmospheric profiles, LST, and LSE with a first-guess LST value. The limitations of the adapted method are that it requires the minimum LSE in the spectral interval of 800–950 cm−1 larger than 0.95 and it has not been extended for off-nadir measurements. PMID:27187408

  7. Retrieving Land Surface Temperature from Hyperspectral Thermal Infrared Data Using a Multi-Channel Method.

    PubMed

    Zhong, Xinke; Huo, Xing; Ren, Chao; Labed, Jelila; Li, Zhao-Liang

    2016-05-13

    Land Surface Temperature (LST) is a key parameter in climate systems. The methods for retrieving LST from hyperspectral thermal infrared data either require accurate atmospheric profile data or require thousands of continuous channels. We aim to retrieve LST for natural land surfaces from hyperspectral thermal infrared data using an adapted multi-channel method taking Land Surface Emissivity (LSE) properly into consideration. In the adapted method, LST can be retrieved by a linear function of 36 brightness temperatures at Top of Atmosphere (TOA) using channels where LSE has high values. We evaluated the adapted method using simulation data at nadir and satellite data near nadir. The Root Mean Square Error (RMSE) of the LST retrieved from the simulation data is 0.90 K. Compared with an LST product from the Spinning Enhanced Visible and Infrared Imager (SEVIRI) on Meteosat, the error in the LST retrieved from the Infared Atmospheric Sounding Interferometer (IASI) is approximately 1.6 K. The adapted method can be used for the near-real-time production of an LST product and to provide the physical method to simultaneously retrieve atmospheric profiles, LST, and LSE with a first-guess LST value. The limitations of the adapted method are that it requires the minimum LSE in the spectral interval of 800-950 cm(-1) larger than 0.95 and it has not been extended for off-nadir measurements.

  8. Multi-channel atomic magnetometer for magnetoencephalography: a configuration study.

    PubMed

    Kim, Kiwoong; Begus, Samo; Xia, Hui; Lee, Seung-Kyun; Jazbinsek, Vojko; Trontelj, Zvonko; Romalis, Michael V

    2014-04-01

    Atomic magnetometers are emerging as an alternative to SQUID magnetometers for detection of biological magnetic fields. They have been used to measure both the magnetocardiography (MCG) and magnetoencephalography (MEG) signals. One of the virtues of the atomic magnetometers is their ability to operate as a multi-channel detector while using many common elements. Here we study two configurations of such a multi-channel atomic magnetometer optimized for MEG detection. We describe measurements of auditory evoked fields (AEF) from a human brain as well as localization of dipolar phantoms and auditory evoked fields. A clear N100m peak in AEF was observed with a signal-to-noise ratio of higher than 10 after averaging of 250 stimuli. Currently the intrinsic magnetic noise level is 4fTHz(-1/2) at 10Hz. We compare the performance of the two systems in regards to current source localization and discuss future development of atomic MEG systems. © 2013.

  9. Multi-channel medical imaging system

    SciTech Connect

    Frangioni, John V.

    2016-05-03

    A medical imaging system provides simultaneous rendering of visible light and fluorescent images. The system may employ dyes in a small-molecule form that remain in a subject's blood stream for several minutes, allowing real-time imaging of the subject's circulatory system superimposed upon a conventional, visible light image of the subject. The system may provide an excitation light source to excite the fluorescent substance and a visible light source for general illumination within the same optical guide used to capture images. The system may be configured for use in open surgical procedures by providing an operating area that is closed to ambient light. The systems described herein provide two or more diagnostic imaging channels for capture of multiple, concurrent diagnostic images and may be used where a visible light image may be usefully supplemented by two or more images that are independently marked for functional interest.

  10. MULTI-CHANNEL ELECTRIC PULSE HEIGHT ANALYZER

    DOEpatents

    Gallagher, J.D. et al.

    1960-11-22

    An apparatus is given for converting binary information into coded decimal form comprising means, in combination with a binary adder, a live memory and a source of bigit pulses, for synchronizing the bigit pulses and the adder output pulses; a source of digit pulses synchronized with every fourth bigit pulse; means for generating a conversion pulse in response to the time coincidence of the adder output pulse and a digit pulse: means having a delay equal to two bigit pulse periods coupling the adder output with the memory; means for promptly impressing said conversion pulse on the input of said memory: and means having a delay equal to one bigit pulse period for again impressing the conversion pulse on the input of the memory whereby a fourth bigit adder pulse results in the insertion into the memory of second, third and fourth bigits.

  11. Multi-channel medical imaging system

    SciTech Connect

    Frangioni, John V

    2013-12-31

    A medical imaging system provides simultaneous rendering of visible light and fluorescent images. The system may employ dyes in a small-molecule form that remain in the subject's blood stream for several minutes, allowing real-time imaging of the subject's circulatory system superimposed upon a conventional, visible light image of the subject. The system may provide an excitation light source to excite the fluorescent substance and a visible light source for general illumination within the same optical guide used to capture images. The system may be configured for use in open surgical procedures by providing an operating area that is closed to ambient light. The systems described herein provide two or more diagnostic imaging channels for capture of multiple, concurrent diagnostic images and may be used where a visible light image may be usefully supplemented by two or more images that are independently marked for functional interest.

  12. Optical-network-connected multi-channel 96-GHz-band distributed radar system

    NASA Astrophysics Data System (ADS)

    Kanno, Atsushi; Kuri, Toshiaki; Kawanishi, Tetsuya

    2015-05-01

    The millimeter-wave (MMW) radar is a promising candidate for high-precision imaging because of its short wavelength and broad range of available bandwidths. In particular in the frequency range of 92-100 GHz, which is regulated for radiolocation, an atmospheric attenuation coefficient less than 1 dB/km limits the imaging range. Therefore, a combination of MMW radar and distributed antenna system directly connected to optical fiber networks can realize both high-precision imaging and large-area surveillance. In this paper, we demonstrate a multi-channel MMW frequency-modulated continuous-wave distributed radar system connected to an analog radio-over-fiber network.

  13. Super multi-channel recording systems with UWB wireless transmitter for BMI.

    PubMed

    Suzuki, Takafumi; Ando, Hiroshi; Yoshida, Takeshi; Sawahata, Hirohito; Kawasaki, Keisuke; Hasegawa, Isao; Matsushita, Kojiro; Hirata, Masayuki; Yoshimine, Toshiki; Takizawa, Kenichi

    2014-01-01

    In order to realize a low-invasive and high accuracy Brain-Machine Interface (BMI) system for clinical applications, a super multi-channel recording system was developed in which 4096 channels of Electrocorticogram (ECoG) signal can be amplified and transmitted to outside the body by using an Ultra Wide Band (UWB) wireless system. Also, a high density, flexible electrode array made by using a Parylene-C substrate was developed that is composed of units of 32-ch recording arrays. We have succeeded in an evaluation test of UWB wireless transmitting using a body phantom system.

  14. Multi-channel optical pyrometer for sub-nanosecond temperature measurements at NDCX-I/II

    SciTech Connect

    Ni, P.A.; Bieniosek, F.M.; Waldron, W.L.

    2011-04-13

    We present a detailed technical description of a fast multi-channel pyrometer designed for warm-dense-matter (WDM) experiments with intense heavy ion beams at the neutralized-drift-compression-experiment linear accelerator (NDCX-I/II) at Lawrence Berkeley National Laboratory (LBNL). The unique features of the described instrument are its sub-nanosecond temporal resolution (100 ps rise-time) and a broad range, 1,500 K - 12,000 K of measurable brightness temperatures in the visible and near-infrared regions of the spectrum. The working scheme, calibration procedure, experimental data obtained with the pyrometer and future applications are presented.

  15. Multi channel quantum defect theory calculations of the Rydberg spectra of HCO

    NASA Astrophysics Data System (ADS)

    Douguet, Nicolas; Orel, Ann

    2014-05-01

    We present a first-principles theoretical study of the photoionization spectra of vibrationally autoionizing Rydberg states converging to excited states of HCO+. The clamped-nuclei scattering matrix, quantum defects parameters and transition dipole moments are explicitly calculated using the complex variational Kohn technique. The multi-channel quantum defect theory and vibrational frame transformation are then used to calculate the absorption spectrum. The results are compared with experimental data on double-resonance spectroscopy of the high Rydberg states of formyl radical. This work is supported by the DOE Office of Basic Energy Science and the National Science Foundation, Grant No's PHY-10-68785 and PHY-11-60611.

  16. Frequency-comb-referenced multi-channel fiber laser for DWDM communication.

    PubMed

    Chun, Byung Jae; Hyun, Sangwon; Kim, Seungman; Kim, Seung-Woo; Kim, Young-Jin

    2013-12-02

    We propose an all-fiber-based multi-channel optical scheme that enables simultaneous generation of multiple continuous-wave laser wavelengths with stabilization to the frequency comb of a femtosecond laser. The intention is to produce highly stable, accurate wavelength channels with immunity to environmental disturbance so as to enhance the transmission capacity of dense wavelength division multiplexing (DWDM) communications. Generated wavelengths lie over a wide spectral range of 5 THz about 1550 nm, each yielding a narrow linewidth of less than 24 kHz with an absolute position uncertainty of ~2.24 × 10¹² (10 s averaging) traceable directly to the atomic Rb clock.

  17. Advances in 3D soil mapping and water content estimation using multi-channel ground-penetrating radar

    NASA Astrophysics Data System (ADS)

    Moysey, S. M.

    2011-12-01

    Multi-channel ground-penetrating radar systems have recently become widely available, thereby opening new possibilities for shallow imaging of the subsurface. One advantage of these systems is that they can significantly reduce survey times by simultaneously collecting multiple lines of GPR reflection data. As a result, it is becoming more practical to complete 3D surveys - particularly in situations where the subsurface undergoes rapid changes, e.g., when monitoring infiltration and redistribution of water in soils. While 3D and 4D surveys can provide a degree of clarity that significantly improves interpretation of the subsurface, an even more powerful feature of the new multi-channel systems for hydrologists is their ability to collect data using multiple antenna offsets. Central mid-point (CMP) surveys have been widely used to estimate radar wave velocities, which can be related to water contents, by sequentially increasing the distance, i.e., offset, between the source and receiver antennas. This process is highly labor intensive using single-channel systems and therefore such surveys are often only performed at a few locations at any given site. In contrast, with multi-channel GPR systems it is possible to physically arrange an array of antennas at different offsets, such that a CMP-style survey is performed at every point along a radar transect. It is then possible to process this data to obtain detailed maps of wave velocity with a horizontal resolution on the order of centimeters. In this talk I review concepts underlying multi-channel GPR imaging with an emphasis on multi-offset profiling for water content estimation. Numerical simulations are used to provide examples that illustrate situations where multi-offset GPR profiling is likely to be successful, with an emphasis on considering how issues like noise, soil heterogeneity, vertical variations in water content and weak reflection returns affect algorithms for automated analysis of the data. Overall

  18. A Novel GBM Saliency Detection Model Using Multi-Channel MRI.

    PubMed

    Banerjee, Subhashis; Mitra, Sushmita; Shankar, B Uma; Hayashi, Yoichi

    2016-01-01

    The automatic computerized detection of regions of interest (ROI) is an important step in the process of medical image processing and analysis. The reasons are many, and include an increasing amount of available medical imaging data, existence of inter-observer and inter-scanner variability, and to improve the accuracy in automatic detection in order to assist doctors in diagnosing faster and on time. A novel algorithm, based on visual saliency, is developed here for the identification of tumor regions from MR images of the brain. The GBM saliency detection model is designed by taking cue from the concept of visual saliency in natural scenes. A visually salient region is typically rare in an image, and contains highly discriminating information, with attention getting immediately focused upon it. Although color is typically considered as the most important feature in a bottom-up saliency detection model, we circumvent this issue in the inherently gray scale MR framework. We develop a novel pseudo-coloring scheme, based on the three MRI sequences, viz. FLAIR, T2 and T1C (contrast enhanced with Gadolinium). A bottom-up strategy, based on a new pseudo-color distance and spatial distance between image patches, is defined for highlighting the salient regions in the image. This multi-channel representation of the image and saliency detection model help in automatically and quickly isolating the tumor region, for subsequent delineation, as is necessary in medical diagnosis. The effectiveness of the proposed model is evaluated on MRI of 80 subjects from the BRATS database in terms of the saliency map values. Using ground truth of the tumor regions for both high- and low- grade gliomas, the results are compared with four highly referred saliency detection models from literature. In all cases the AUC scores from the ROC analysis are found to be more than 0.999 ± 0.001 over different tumor grades, sizes and positions.

  19. A Novel GBM Saliency Detection Model Using Multi-Channel MRI

    PubMed Central

    Banerjee, Subhashis; Mitra, Sushmita; Shankar, B. Uma; Hayashi, Yoichi

    2016-01-01

    The automatic computerized detection of regions of interest (ROI) is an important step in the process of medical image processing and analysis. The reasons are many, and include an increasing amount of available medical imaging data, existence of inter-observer and inter-scanner variability, and to improve the accuracy in automatic detection in order to assist doctors in diagnosing faster and on time. A novel algorithm, based on visual saliency, is developed here for the identification of tumor regions from MR images of the brain. The GBM saliency detection model is designed by taking cue from the concept of visual saliency in natural scenes. A visually salient region is typically rare in an image, and contains highly discriminating information, with attention getting immediately focused upon it. Although color is typically considered as the most important feature in a bottom-up saliency detection model, we circumvent this issue in the inherently gray scale MR framework. We develop a novel pseudo-coloring scheme, based on the three MRI sequences, viz. FLAIR, T2 and T1C (contrast enhanced with Gadolinium). A bottom-up strategy, based on a new pseudo-color distance and spatial distance between image patches, is defined for highlighting the salient regions in the image. This multi-channel representation of the image and saliency detection model help in automatically and quickly isolating the tumor region, for subsequent delineation, as is necessary in medical diagnosis. The effectiveness of the proposed model is evaluated on MRI of 80 subjects from the BRATS database in terms of the saliency map values. Using ground truth of the tumor regions for both high- and low- grade gliomas, the results are compared with four highly referred saliency detection models from literature. In all cases the AUC scores from the ROC analysis are found to be more than 0.999 ± 0.001 over different tumor grades, sizes and positions. PMID:26752735

  20. A multi-channel integrated readout circuit (MIROC) chip for solid state charged particle detectors

    NASA Astrophysics Data System (ADS)

    He, Xiang

    2011-12-01

    Various electronic amplifier systems have been developed during the past years for solid state detectors for energetic charged particle detection. Most of them were based on the design of discrete parts or high performance hybrid packaged chips. With rapid development of modern integrated circuit industry, there are more and more integrated systems built for such applications. This work describes a novel multi-channel integrated readout circuit (MIROC) mixed-signal ASIC for solid stage charged particle detectors. The chip contains nineteen analog amplifier channels including the test channel, three on-chip 8-bit ADCs, each equipped with a 8-bit parallel-to-serial shift register, three 19-input analog multiplexers, and other digital control logic modules. This was the first known integrated readout system with multiple channels and multiple ADCs, by the time the project started. The chip is designed with special interest in 1MeV electrons. It is a highly integrated system that only requires minimal external controls, which could significantly reduce cost, space, power and total mass of the readout system, and reduce the development cycle of new instruments. MIROC chip was fabricated with IBM 7WL 0.18microm SiGe BiCMOS technology through MOSIS MEP research license, and has been tested, with key components characterized. Measured only 4mmx4mm, this highly integrated readout system has a FWHM noise below 20keV. The four configurable conversion gain levels of the amplifier chains, measured to be 164mV/MeV, 378mV/MeV, 611mV/MeV and 950mV/MeV, make the chip capable of studying energetic charged particles over the range of 100keV up to 6MeV.

  1. Automated analysis of multi-channel EEG in preterm infants.

    PubMed

    Murphy, Keelin; Stevenson, Nathan J; Goulding, Robert M; Lloyd, Rhodri O; Korotchikova, Irina; Livingstone, Vicki; Boylan, Geraldine B

    2015-09-01

    To develop and validate two automatic methods for the detection of burst and interburst periods in preterm eight-channel electroencephalographs (EEG). To perform a detailed analysis of interobserver agreement on burst and interburst periods and use this as a benchmark for the performance of the automatic methods. To examine mathematical features of the EEG signal and their potential correlation with gestational age. Multi-channel EEG from 36 infants, born at less than 30 weeks gestation was utilised, with a 10 min artifact-free epoch selected for each subject. Three independent expert observers annotated all EEG activity bursts in the dataset. Two automatic algorithms for burst/interburst detection were applied to the EEG data and their performances were analysed and compared with interobserver agreement. A total of 12 mathematical features of the EEG signal were calculated and correlated with gestational age. The mean interobserver agreement was found to be 77% while mean algorithm/observer agreement was 81%. Six of the mathematical features calculated (spectral entropy, Higuchi fractal dimension, spectral edge frequency, variance, extrema median and Hilberts transform amplitude) were found to have significant correlation with gestational age. Automatic detection of burst/interburst periods has been performed in multi-channel EEG of 36 preterm infants. The algorithm agreement with expert observers is found to be on a par with interobserver agreement. Mathematical features of EEG have been calculated which show significant correlation with gestational age. Automatic analysis of preterm multi-channel EEG is possible. The methods described here have the potential to be incorporated into a fully automatic system to quantitatively assess brain maturity from preterm EEG. Copyright © 2015 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  2. Multi-channel analysis of passive surface waves based on cross-correlations

    NASA Astrophysics Data System (ADS)

    Cheng, F.; Xia, J.; Xu, Z.; Hu, Y.

    2015-12-01

    Traditional active seismic survey can no longer be properly applied in highly populated urban areas due to restrictions in modern civilian life styles. Passive seismic methods, however, have gained much more attention from the engineering geophysics community because of their environmental friendly and deeper investigation depth. Due to extracting signal from noise has never been as comfortable as that in active seismic survey, how to make it more efficiently and accurately has been emphasized. We propose a multi-channel analysis of passive surface waves (MAPW) based on long noise sequences cross-correlations to meet the demand for increasing investigation depth by acquiring surface-wave data at a relative low-frequency range (1 Hz ≤ f ≤ 10 Hz) in urban areas. We utilize seismic interferometry to produce common virtual source gathers from one-hour-long noise records and do dispersion measurements by using the classic passive multi-channel analysis of surface waves (PMASW). We used synthetic tests to demonstrate the advantages of MAPW for various noise distributions. Results show that our method has the superiority of maximizing the analysis accuracy. Finally, we used two field data applications to demonstrate the advantages of our MAPW over the classic PMASW on isolating azimuth of the predominant noise sources and the effectivity of combined survey of active multi-channel analysis of surface waves (MASW) and MAPW. We suggest, for the field operation using MAPW, that a parallel receiver line which is close to a main road or river, if any, with one or two hours noise observation will be an effective means for an unbiased dispersion image. Keywords: passive seismic method, MAPW, MASW, cross-correlation, directional noise source, spatial-aliasing effects, inversion

  3. Efficient sequential compression of multi-channel biomedical signals.

    PubMed

    Capurro, Ignacio; Lecumberry, Federico; Martin, Alvaro; Ramirez, Ignacio; Rovira, Eugenio; Seroussi, Gadiel

    2016-06-21

    This work proposes lossless and near-lossless compression algorithms for multi-channel biomedical signals. The algorithms are sequential and efficient, which makes them suitable for low-latency and low-power signal transmission applications. We make use of information theory and signal processing tools (such as universal coding, universal prediction, and fast online implementations of multivariate recursive least squares), combined with simple methods to exploit spatial as well as temporal redundancies typically present in biomedical signals. The algorithms are tested with publicly available electroencephalogram and electrocardiogram databases, surpassing in all cases the current state of the art in near-lossless and lossless compression ratios.

  4. A multi-channel setup to study fractures in scintillators

    NASA Astrophysics Data System (ADS)

    Tantot, A.; Bouard, C.; Briche, R.; Lefèvre, G.; Manier, B.; Zaïm, N.; Deschanel, S.; Vanel, L.; Di Stefano, P. C. F.

    2016-12-01

    To investigate fractoluminescence in scintillating crystals used for particle detection, we have developed a multi-channel setup built around samples of double-cleavage drilled compression (DCDC) geometry in a controllable atmosphere. The setup allows the continuous digitization over hours of various parameters, including the applied load, and the compressive strain of the sample, as well as the acoustic emission. Emitted visible light is recorded with nanosecond resolution, and crack propagation is monitored using infrared lighting and camera. An example of application to \\text{B}{{\\text{i}}4}\\text{G}{{\\text{e}}3}{{\\text{O}}12} (BGO) is provided.

  5. Multi-Channel Adjustable DC Power Supply with Single Transformer Based on Spectral Separation

    NASA Astrophysics Data System (ADS)

    Benfeng, Zhang; Huafeng, Li; Sunan, Li

    2014-01-01

    To meet the need of multi-channel DC power supply to activate multiple macro fiber composite (MFC) material simultaneously, a novel multi-channel adjustable DC supply using single-input single-output transformer based on spectral separation is proposed. A hybrid signal containing multiple frequency bands is boosted to obtain a high-voltage signal without bands change. Several frequency selection circuits are then used to separate individual signals in different frequency band from the high-voltage signal. Finally, these signals are rectified and filtered respectively to obtain multiple channel DC voltages. The feasibility of the proposed scheme is analyzed theoretically and verified by simulation. The hybrid signal containing multiple frequency bands is constructed by MCU (Micro Control Unit) and boosted using push-pull boost circuit. Low-pass, band-pass and high-pass frequency selection circuits are used to obtain the individual high-voltage signal in different frequency bands, and the amplitude frequency response characteristics of these filters are simulated using PSpice. Experimental results prove that each part of the scheme runs reliable and the output is stable and adjustable.

  6. Envelope Interactions in Multi-Channel Amplitude Modulation Frequency Discrimination by Cochlear Implant Users

    PubMed Central

    2015-01-01

    Rationale Previous cochlear implant (CI) studies have shown that single-channel amplitude modulation frequency discrimination (AMFD) can be improved when coherent modulation is delivered to additional channels. It is unclear whether the multi-channel advantage is due to increased loudness, multiple envelope representations, or to component channels with better temporal processing. Measuring envelope interference may shed light on how modulated channels can be combined. Methods In this study, multi-channel AMFD was measured in CI subjects using a 3-alternative forced-choice, non-adaptive procedure (“which interval is different?”). For the reference stimulus, the reference AM (100 Hz) was delivered to all 3 channels. For the probe stimulus, the target AM (101, 102, 104, 108, 116, 132, 164, 228, or 256 Hz) was delivered to 1 of 3 channels, and the reference AM (100 Hz) delivered to the other 2 channels. The spacing between electrodes was varied to be wide or narrow to test different degrees of channel interaction. Results Results showed that CI subjects were highly sensitive to interactions between the reference and target envelopes. However, performance was non-monotonic as a function of target AM frequency. For the wide spacing, there was significantly less envelope interaction when the target AM was delivered to the basal channel. For the narrow spacing, there was no effect of target AM channel. The present data were also compared to a related previous study in which the target AM was delivered to a single channel or to all 3 channels. AMFD was much better with multiple than with single channels whether the target AM was delivered to 1 of 3 or to all 3 channels. For very small differences between the reference and target AM frequencies (2–4 Hz), there was often greater sensitivity when the target AM was delivered to 1 of 3 channels versus all 3 channels, especially for narrowly spaced electrodes. Conclusions Besides the increased loudness, the present results

  7. Co-integrating plasmonics with Si3N4 photonics towards a generic CMOS compatible PIC platform for high-sensitivity multi-channel biosensors: the H2020 PlasmoFab approach (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Tsiokos, Dimitris M.; Dabos, George; Ketzaki, Dimitra; Weeber, Jean-Claude; Markey, Laurent; Dereux, Alain; Giesecke, Anna Lena; Porschatis, Caroline; Chmielak, Bartos; Wahlbrink, Thorsten; Rochracher, Karl; Pleros, Nikos

    2017-05-01

    Silicon photonics meet most fabrication requirements of standard CMOS process lines encompassing the photonics-electronics consolidation vision. Despite this remarkable progress, further miniaturization of PICs for common integration with electronics and for increasing PIC functional density is bounded by the inherent diffraction limit of light imposed by optical waveguides. Instead, Surface Plasmon Polariton (SPP) waveguides can guide light at sub-wavelength scales at the metal surface providing unique light-matter interaction properties, exploiting at the same time their metallic nature to naturally integrate with electronics in high-performance ASPICs. In this article, we demonstrate the main goals of the recently introduced H2020 project PlasmoFab towards addressing the ever increasing needs for low energy, small size and high performance mass manufactured PICs by developing a revolutionary yet CMOS-compatible fabrication platform for seamless co-integration of plasmonics with photonic and supporting electronic. We demonstrate recent advances on the hosting SiN photonic hosting platform reporting on low-loss passive SiN waveguide and Grating Coupler circuits for both the TM and TE polarization states. We also present experimental results of plasmonic gold thin-film and hybrid slot waveguide configurations that can allow for high-sensitivity sensing, providing also the ongoing activities towards replacing gold with Cu, Al or TiN metal in order to yield the same functionality over a CMOS metallic structure. Finally, the first experimental results on the co-integrated SiN+plasmonic platform are demonstrated, concluding to an initial theoretical performance analysis of the CMOS plasmo-photonic biosensor that has the potential to allow for sensitivities beyond 150000nm/RIU.

  8. A wireless multi-channel bioimpedance measurement system for personalized healthcare and lifestyle.

    PubMed

    Ramos, Javier; Ausín, José Luis; Lorido, Antonio Manuel; Redondo, Francisco; Duque-Carrillo, Juan Francisco

    2013-01-01

    Miniaturized, noninvasive, wearable sensors constitute a fundamental prerequisite for pervasive, predictive, and preventive healthcare systems. In this sense, this paper presents the design, realization, and evaluation of a wireless multi-channel measurement system based on a cost-effective high-performance integrated circuit for electrical bioimpedance (EBI) measurements in the frequency range from 1 kHz to 1 MHz. The resulting on-chip spectrometer provides high measuring EBI capabilities and together with a low-cost, commercially available radio frequency transceiver device. It provides reliable wireless communication, constitutes the basic node to build EBI wireless sensor networks (EBI-WSNs). The proposed EBI-WSN behaves as a high-performance wireless multi-channel EBI spectrometer, where the number of channels is completely scalable and independently configurable to satisfy specific measurement requirements of each individual. A prototype of the EBI node leads to a very small printed circuit board of approximately 8 cm2 including chip-antenna, which can operate several years on one 3-V coin cell battery and make it suitable for long-term preventive healthcare monitoring.

  9. A duple watermarking strategy for multi-channel quantum images

    NASA Astrophysics Data System (ADS)

    Yan, Fei; Iliyasu, Abdullah M.; Sun, Bo; Venegas-Andraca, Salvador E.; Dong, Fangyan; Hirota, Kaoru

    2015-05-01

    Utilizing a stockpile of efficient transformations consisting of channel of interest, channel swapping, and quantum Fourier transforms, a duple watermarking strategy on multi-channel quantum images is proposed. It embeds the watermark image both into the spatial domain and the frequency domain of the multi-channel quantum carrier image, while also providing a quantum measurement-based algorithm to generate an unknown key that is used to protect the color information, which accompanies another key that is mainly used to scramble the spatial content of the watermark image in order to further safeguard the copyright of the carrier image. Simulation-based experiments using a watermark logo and nine building images as watermark image and carrier images, respectively, offer a duple protection for the copyright of carrier images in terms of the visible quality of the watermarked images. The proposed stratagem advances available literature in the quantum watermarking research field and sets the stage for the applications aimed at quantum data protection.

  10. Multi-channel fiber photometry for population neuronal activity recording.

    PubMed

    Guo, Qingchun; Zhou, Jingfeng; Feng, Qiru; Lin, Rui; Gong, Hui; Luo, Qingming; Zeng, Shaoqun; Luo, Minmin; Fu, Ling

    2015-10-01

    Fiber photometry has become increasingly popular among neuroscientists as a convenient tool for the recording of genetically defined neuronal population in behaving animals. Here, we report the development of the multi-channel fiber photometry system to simultaneously monitor neural activities in several brain areas of an animal or in different animals. In this system, a galvano-mirror modulates and cyclically couples the excitation light to individual multimode optical fiber bundles. A single photodetector collects excited light and the configuration of fiber bundle assembly and the scanner determines the total channel number. We demonstrated that the system exhibited negligible crosstalk between channels and optical signals could be sampled simultaneously with a sample rate of at least 100 Hz for each channel, which is sufficient for recording calcium signals. Using this system, we successfully recorded GCaMP6 fluorescent signals from the bilateral barrel cortices of a head-restrained mouse in a dual-channel mode, and the orbitofrontal cortices of multiple freely moving mice in a triple-channel mode. The multi-channel fiber photometry system would be a valuable tool for simultaneous recordings of population activities in different brain areas of a given animal and different interacting individuals.

  11. Multi-channel fiber photometry for population neuronal activity recording

    PubMed Central

    Guo, Qingchun; Zhou, Jingfeng; Feng, Qiru; Lin, Rui; Gong, Hui; Luo, Qingming; Zeng, Shaoqun; Luo, Minmin; Fu, Ling

    2015-01-01

    Fiber photometry has become increasingly popular among neuroscientists as a convenient tool for the recording of genetically defined neuronal population in behaving animals. Here, we report the development of the multi-channel fiber photometry system to simultaneously monitor neural activities in several brain areas of an animal or in different animals. In this system, a galvano-mirror modulates and cyclically couples the excitation light to individual multimode optical fiber bundles. A single photodetector collects excited light and the configuration of fiber bundle assembly and the scanner determines the total channel number. We demonstrated that the system exhibited negligible crosstalk between channels and optical signals could be sampled simultaneously with a sample rate of at least 100 Hz for each channel, which is sufficient for recording calcium signals. Using this system, we successfully recorded GCaMP6 fluorescent signals from the bilateral barrel cortices of a head-restrained mouse in a dual-channel mode, and the orbitofrontal cortices of multiple freely moving mice in a triple-channel mode. The multi-channel fiber photometry system would be a valuable tool for simultaneous recordings of population activities in different brain areas of a given animal and different interacting individuals. PMID:26504642

  12. A multi-channel fully differential programmable integrated circuit for neural recording application

    NASA Astrophysics Data System (ADS)

    Yun, Gui; Xu, Zhang; Yuan, Wang; Ming, Liu; Weihua, Pei; Kai, Liang; Suibiao, Huang; Bin, Li; Hongda, Chen

    2013-10-01

    A multi-channel, fully differential programmable chip for neural recording application is presented. The integrated circuit incorporates eight neural recording amplifiers with tunable bandwidth and gain, eight 4th-order Bessel switch capacitor filters, an 8-to-1 analog time-division multiplexer, a fully differential successive approximation register analog-to-digital converter (SAR ADC), and a serial peripheral interface for communication. The neural recording amplifier presents a programmable gain from 53 dB to 68 dB, a tunable low cut-off frequency from 0.1 Hz to 300 Hz, and 3.77 μVrms input-referred noise over a 5 kHz bandwidth. The SAR ADC digitizes signals at maximum sampling rate of 20 kS/s per channel and achieves an ENOB of 7.4. The integrated circuit is designed and fabricated in 0.18-μm CMOS mix-signal process. We successfully performed a multi-channel in-vivo recording experiment from a rat cortex using the neural recording chip.

  13. Multi-channel metallic electrode for threshold stimulation of frog's retina.

    PubMed

    Kuras, A; Gutmaniene, N

    1997-07-18

    A simple method for making a stimulating multi-channel metallic electrode is proposed. The method uses furnace-shaped multiple fine glass tubes as channel guides for inserted tungsten wires that are pulled as a unit to produce multi-channel metallic electrode with a tapered tip. By shortening the tip, the desired inter-channels distances (from tens to hundreds of micrometers) can be established with a high degree of accuracy. Such an electrode was used to stimulate the layer of ganglion cells in a frog's retina. The responses to stimuli were recorded extracellularly in the contralateral tectum from the terminal arborizations of the excited ganglion cells' axons. A larger area of the retina may be excited when several channels are used as a cathode and several others as an anode. By varying the stimulating pairs of the channels it is possible to change the site of excitation without displacing the electrode. Separate ganglion cells may be stimulated, provided the appropriate pair of channels is selected. In this case 'all-or-none' responses to the threshold stimuli are obtained in the tectum. The artefact of the stimulus is diminished effectively by joining additional channels to the anodic one.

  14. [Development of multi-channels cardiac electrophysiological polygraph with LabVIEW as software platform and its clinical application].

    PubMed

    Fan, Shounian; Jiang, Yi; Jiang, Chenxi; Yang, Tianhe; Zhang, Chengyun; Liu, Junshi; Wu, Qiang; Zheng, Yaxi; Liu, Xiaoqiao

    2004-10-01

    Polygraph has become a necessary instrument in interventional cardiology and fundamental research of medicine up to the present. In this study, a LabView development system (DS) (developed by NI in U.S.) used as software platform, a DAQ data acquisition module and universal computer used as hardware platform, were creatively coupled with our self-made low noise multi-channels preamplifier to develop Multi-channels electrocardiograph. The device possessed the functions such as real time display of physiological process, digit highpass and lowpass, 50Hz filtered and gain adjustment, instant storing, random playback and printing, and process control stimulation. Besides, it was small-sized, economically practical and easy to operate. It could advance the spread of cardiac intervention treatment in hospitals.

  15. Stacked, Filtered Multi-Channel X-Ray Diode Array

    SciTech Connect

    MacNeil, Lawrence P.; Dutra, Eric C.; Raphaelian, Mark; Compton, Steven; Jacoby, Barry

    2015-08-01

    This system meets the need for a low-cost, robust X-ray diode array to use for experiments in hostile environments on multiple platforms, and for experiments utilizing forces that may destroy the diode(s). Since these uses require a small size with a minimal single line-of-sight, a parallel array often cannot be used. So a stacked, filtered multi-channel X-ray diode array was developed that was called the MiniXRD. The design was modeled, built, and tested at National Security Technologies, LLC (NSTec) Livermore Operations (LO) to determine fundamental characteristics. Then, several different systems were fielded as ancillary “ridealong” diagnostics at several national facilities to allow us to iteratively improve the design and usability. Presented here are design considerations and experimental results. This filtered diode array is currently at Technical Readiness Level (TRL) 6.

  16. Multi-channel detector readout method and integrated circuit

    DOEpatents

    Moses, William W.; Beuville, Eric; Pedrali-Noy, Marzio

    2004-05-18

    An integrated circuit which provides multi-channel detector readout from a detector array. The circuit receives multiple signals from the elements of a detector array and compares the sampled amplitudes of these signals against a noise-floor threshold and against one another. A digital signal is generated which corresponds to the location of the highest of these signal amplitudes which exceeds the noise floor threshold. The digital signal is received by a multiplexing circuit which outputs an analog signal corresponding the highest of the input signal amplitudes. In addition a digital control section provides for programmatic control of the multiplexer circuit, amplifier gain, amplifier reset, masking selection, and test circuit functionality on each input thereof.

  17. A calibration method of the multi-channel imaging lidar

    NASA Astrophysics Data System (ADS)

    Xu, Weiming; Liu, Jun; Shu, Rong

    2014-06-01

    We design a kind of imaging LiDAR with sixteen channels, which consists of a fiber laser source, dual scanning galvanometers, range measurement circuits and information processing circuits etc. The image LiDAR provides sixteen range measurements for one laser shot and the distance accuracy of each channel is about 4cm. This paper provides a calibrate method to correct point cloud images captured with the multi-channel LiDAR. The method needs to construct different slanted planes to cover the imaging field, and establish precise plane equations in the known ground coordinates, then fit planes with point clouds data and calculate correction parameters of all channels through the error model. The image accuracy is better than 5cm processed by this calibration method.

  18. Multi-channel detector readout method and integrated circuit

    SciTech Connect

    Moses, William W.; Beuville, Eric; Pedrali-Noy, Marzio

    2006-12-12

    An integrated circuit which provides multi-channel detector readout from a detector array. The circuit receives multiple signals from the elements of a detector array and compares the sampled amplitudes of these signals against a noise-floor threshold and against one another. A digital signal is generated which corresponds to the location of the highest of these signal amplitudes which exceeds the noise floor threshold. The digital signal is received by a multiplexing circuit which outputs an analog signal corresponding the highest of the input signal amplitudes. In addition a digital control section provides for programmatic control of the multiplexer circuit, amplifier gain, amplifier reset, masking selection, and test circuit functionality on each input thereof.

  19. Miniaturized multi channel infrared optical gas sensor system

    NASA Astrophysics Data System (ADS)

    Wöllenstein, Jürgen; Eberhardt, Andre; Rademacher, Sven; Schmitt, Katrin

    2011-06-01

    Infrared spectroscopy uses the characteristic absorption of the molecules in the mid infrared and allows the determination of the gases and their concentration. Especially by the absorption at longer wavelengths between 8 μm and 12 μm, the so called "fingerprint" region, the molecules can be measured with highest selectivity. We present an infrared optical filter photometer for the analytical determination of trace gases in the air. The challenge in developing the filter photometer was the construction of a multi-channel system using a novel filter wheel concept - which acts as a chopper too- in order to measure simultaneously four gases: carbon monoxide, carbon dioxide, methane and ammonia. The system consists of a broadband infrared emitter, a long path cell with 1.7m optical path length, a filter wheel and analogue and digital signal processing. Multi channel filter photometers normally need one filter and one detector per target gas. There are small detection units with one, two or more detectors with integrated filters available on the market. One filter is normally used as reference at a wavelength without any cross-sensitivities to possible interfering gases (e.g. at 3.95 μm is an "atmospheric window" - a small spectral band without absorbing gases in the atmosphere). The advantage of a filter-wheel set-up is that a single IR-detector can be used, which reduces the signal drift enormously. Pyroelectric and thermopile detectors are often integrated in these kinds of spectrometers. For both detector types a modulation of the light is required and can be done - without an additional chopper - with the filter wheel.

  20. Integrated multi-channel nano-engineered optical hydrogen and temperature sensor detection systems for launch vehicles

    NASA Astrophysics Data System (ADS)

    Alam, M. Z.; Moreno, J.; Aitchison, J. S.; Mojahedi, M.; Kazemi, A. A.

    2008-08-01

    Launch vehicles and other satellite users need launch services that are highly reliable, less complex, easier to test, and cost effective. Being a very small molecule, hydrogen is prone to leakage through seals and micro-cracks. Hydrogen detection in space application is very challenging; public acceptance of hydrogen fuel would require the integration of a reliable hydrogen safety sensor. For detecting leakage of cryogenic fluids in spaceport facilities, launch vehicle industry and aerospace agencies are currently relying heavily on the bulky mass spectrometers, which fill one or more equipment racks, and weigh several hundred kilograms. Therefore, there is a critical need for miniaturized sensors and instruments suitable for use in space applications. This paper describes a novel multi-channel integrated nano-engineered optical sensor to detect hydrogen and monitor the temperature. The integrated optic sensor is made of multi-channel waveguide elements that measure hydrogen concentration in real Time. Our sensor is based on the use of a high index waveguide with a Ni/Pd overlay to detect hydrogen. When hydrogen is absorbed into the Ni/Pd alloy there is a change in the absorption of the material and the optical signal in the waveguide is increased. Our design uses a thin alloy (few nanometers thick) overlay which facilitates the absorption of the hydrogen and will result in a response time of approximately few seconds. Like other Pd/Pd-Ni based sensors the device response varies with temperature and hence the effects of temperature variations must be taken into account. One solution to this problem is simultaneous measurement of temperature in addition to hydrogen concentration at the same vicinity. Our approach here is to propose a temperature sensor that can easily be integrated on the same platform as the hydrogen sensor reported earlier by our group. One suitable choice of material system is silicon on insulator (SOI). Here, we propose a micro ring resonators

  1. Non cross talk multi-channel photomultiplier using guided electron multipliers

    DOEpatents

    Gomez, Javier; Majewski, Stanislaw; Weisenberger, Andrew G.

    1995-01-01

    An improved multi-channel electron multiplier is provided that exhibits zero cross-talk and high rate operation. Resistive material input and output masks are employed to control divergence of electrons. Electron multiplication takes place in closed channels. Several embodiments are provided for these channels including a continuous resistive emissive multiplier and a discrete resistive multiplier with discrete dynode chains interspaced with resistive layers-masks. Both basic embodiments provide high gain multiplication of electrons without accumulating surface charges while containing electrons to their proper channels to eliminate cross-talk. The invention can be for example applied to improve the performance of ion mass spectrometers, positron emission tomography devices, in DNA sequencing and other beta radiography applications and in many applications in particle physics.

  2. Non-cross talk multi-channel photomultiplier using guided electron multipliers

    DOEpatents

    Gomez, J.; Majewski, S.; Weisenberger, A.G.

    1995-09-26

    An improved multi-channel electron multiplier is provided that exhibits zero cross-talk and high rate operation. Resistive material input and output masks are employed to control divergence of electrons. Electron multiplication takes place in closed channels. Several embodiments are provided for these channels including a continuous resistive emissive multiplier and a discrete resistive multiplier with discrete dynode chains interspaced with resistive layers-masks. Both basic embodiments provide high gain multiplication of electrons without accumulating surface charges while containing electrons to their proper channels to eliminate cross-talk. The invention can be for example applied to improve the performance of ion mass spectrometers, positron emission tomography devices, in DNA sequencing and other beta radiography applications and in many applications in particle physics. 28 figs.

  3. Multi-channel silicon photonic receiver based on ring-resonators.

    PubMed

    Fang, Qing; Phang, Yu Ting; Tan, Chee Wei; Liow, Tsung-Yang; Yu, Ming Bin; Lo, Guo Qiang; Kwong, Dim Lee

    2010-06-21

    We demonstrated a high performance monolithically integrated multi-channel receiver fabricated on the SOI platform. This receiver is composed of a 1 x 8 Si-based ring-resonators filter and an array of high speed waveguided Ge-on-Si photodetectors. The optical channel spacing is about 1.5 nm. The responsivity of Ge-on-Si photodetector is about 1.0 A/W at the wavelength range of 1554 nm to 1564 nm. Each channel is capable of operating at a data rate of 20 Gbps, resulting in an aggregate data rate of 160 Gbps. At a BER of 1 x 10(-11), the receiver showed an optical input sensitivity of between -20 dBm and -21 dBm for each channel at 10 Gbps data rate.

  4. Multi-channel PMMA microfluidic biosensor with integrated IDUAs for electrochemical detection

    PubMed Central

    Wongkaew, Nongnoot; He, Peng; Kurth, Vanessa; Surareungchai, Werasak; Baeumner, Antje J.

    2013-01-01

    A novel multi-channel poly(methyl methacrylate) (PMMA) microfluidic biosensor with interdigitated ultramicroelectrode arrays (IDUAs) for electrochemical detection was developed. The focus of the development was a simple fabrication procedure and the realization of a reliable large IDUA that can provide detection simultaneously to several microchannels. As proof of concept, five microchannels are positioned over a large single IDUA where the channels are parallel with the length of electrode finger. The IDUAs were fabricated on the PMMA cover piece and bonded to a PMMA substrate containing the microfluidic channels using UV/ozone-assisted thermal bonding. Conditions of device fabrication were optimized realizing a rugged large IDUA within a bonded PMMA device. Gold adhesion to the PMMA, protective coatings and pressure during bonding were optimized. Its electrochemical performance was studied using amperometric detection of potassium ferri and ferro hexacyanide. Cumulative signals within the same chip showed very good linearity over a range of 0 - 38 μM (R2 = 0.98) and a limit of detection of 3.48 μM. The bonding of the device was optimized so that no cross-talk between the channels was observed which otherwise would have resulted in unreliable electrochemical responses. The highly reproducible signals achieved were comparable to those obtained with separate single-channel devices. Subsequently, the multi-channel microfluidic chip was applied to a model bioanalytical detection strategy, i.e. the quantification of specific nucleic acid sequences using a sandwich approach. Here probe-coated paramagnetic beads and probe-tagged liposomes entrapping ferri/ferro hexacyanide as the redox marker were used to bind to a single stranded DNA sequence. Flow rates of the non-ionic detergent n-octyl-β-D-glucopyranoside (OG) for liposome lysis were optimized and the detection of the target sequences was carried out coulometrically within 250 s and with a limit of detection of 12

  5. An Efficient, Highly Flexible Multi-Channel Digital Downconverter Architecture

    NASA Technical Reports Server (NTRS)

    Goodhart, Charles E.; Soriano, Melissa A.; Navarro, Robert; Trinh, Joseph T.; Sigman, Elliott H.

    2013-01-01

    In this innovation, a digital downconverter has been created that produces a large (16 or greater) number of output channels of smaller bandwidths. Additionally, this design has the flexibility to tune each channel independently to anywhere in the input bandwidth to cover a wide range of output bandwidths (from 32 MHz down to 1 kHz). Both the flexibility in channel frequency selection and the more than four orders of magnitude range in output bandwidths (decimation rates from 32 to 640,000) presented significant challenges to be solved. The solution involved breaking the digital downconversion process into a two-stage process. The first stage is a 2 oversampled filter bank that divides the whole input bandwidth as a real input signal into seven overlapping, contiguous channels represented with complex samples. Using the symmetry of the sine and cosine functions in a similar way to that of an FFT (fast Fourier transform), this downconversion is very efficient and gives seven channels fixed in frequency. An arbitrary number of smaller bandwidth channels can be formed from second-stage downconverters placed after the first stage of downconversion. Because of the overlapping of the first stage, there is no gap in coverage of the entire input bandwidth. The input to any of the second-stage downconverting channels has a multiplexer that chooses one of the seven wideband channels from the first stage. These second-stage downconverters take up fewer resources because they operate at lower bandwidths than doing the entire downconversion process from the input bandwidth for each independent channel. These second-stage downconverters are each independent with fine frequency control tuning, providing extreme flexibility in positioning the center frequency of a downconverted channel. Finally, these second-stage downconverters have flexible decimation factors over four orders of magnitude The algorithm was developed to run in an FPGA (field programmable gate array) at input data sampling rates of up to 1,280 MHz. The current implementation takes a 1,280-MHz real input, and first breaks it up into seven 160-MHz complex channels, each spaced 80 MHz apart. The eighth channel at baseband was not required for this implementation, and led to more optimization. Afterwards, 16 second stage narrow band channels with independently tunable center frequencies and bandwidth settings are implemented A future implementation in a larger Xilinx FPGA will hold up to 32 independent second-stage channels.

  6. Design and performance of a fiber array coupled multi-channel photon counting, 3D imaging, airborne lidar system

    NASA Astrophysics Data System (ADS)

    Huang, Genghua; Shu, Rong; Hou, Libing; Li, Ming

    2014-06-01

    Photon counting lidar has an ultra-high sensitivity which can be hundreds even thousands of times higher than the linear detection lidar. It can significantly increase the system's capability of detection rang and imaging density, saving size and power consumings in airborne or space-borne applications. Based on Geiger-mode Si avalanche photodiodes (Si-APD), a prototype photon counting lidar which used 8 APDs coupled with a 1×8-pixel fiber array has been made in June, 2011. The experiments with static objects showed that the photon counting lidar could operate in strong solar background with 0.04 receiving photoelectrons on average. Limited by less counting times in moving platforms, the probability of detection and the 3D imaging density would be lower than that in static platforms. In this paper, a latest fiber array coupled multi-channel photon counting, 3D imaging, airborne lidar system is introduced. The correlation range receiver algorithm of photon counting 3D imaging is improved for airborne signal photon events extraction and noise filter. The 3D imaging experiments in the helicopter shows that the false alarm rate is less than 6×10-7, and the correct rate is better than 99.9% with 4 received photoelectrons and 0.7MHz system noise on average.

  7. A customizable multi-channel loudness compensation method based on WDRC for digital hearing aids

    NASA Astrophysics Data System (ADS)

    Hu, Jiebin; Wang, Mingjiang; Ma, Min

    2017-08-01

    Loudness compensation is the most significant signal processing algorithm in digital hearing aids at present. An algorithm of multi-channel loudness compensation for embedded system has been put forward in this paper. The number of channels is customizable in this algorithm. The algorithm can set different number and different width of channels for each patient based on frequency domain wide dynamic range compression. First, according to the requirement of patient to divide the frequency domain into multiple unequal frequency bands. And then calculate the gain of each channel according to the input-output curve of sound pressure level. Finally, the time-domain impulse response of gain is computed from Mel filter banks. It is used in conjunction with speech enhancement processing in hearing aids. Simulation results show that the algorithm can effectively enhance the loudness for different frequencies.

  8. Multi-channel quantum dragons from rectangular nanotubes with even-odd structure

    NASA Astrophysics Data System (ADS)

    Inkoom, Godfred; Novotny, Mark

    Recently, a large class of nanostructures called quantum dragons have been discovered theoretically. Quantum dragons are nanostuctures with correlated disorder but have an electron transmission probability  (E) =1 for all energies E when connected to idealized leads. Hence for a single channel, the electrical conductance for a two-probe measurement should give the quantum of conductance Go =2e2/h . The time independent Schrödinger equation for the single band tight binding model is solved exactly to obtain  (E) . We have generalized the matrix method and the mapping methods of in order to study multi-channel quantum dragons for rectangular nanotubes with even-odd structure. The studies may be relevant for experimental rectangular nanotubes, such as MgO, copper phthalocyanine or some types of graphyne.. Supported in part by NSF Grant DMR-1206233.

  9. A wireless multi-channel neural amplifier for freely moving animals.

    PubMed

    Szuts, Tobi A; Fadeyev, Vitaliy; Kachiguine, Sergei; Sher, Alexander; Grivich, Matthew V; Agrochão, Margarida; Hottowy, Pawel; Dabrowski, Wladyslaw; Lubenov, Evgueniy V; Siapas, Athanassios G; Uchida, Naoshige; Litke, Alan M; Meister, Markus

    2011-02-01

    Conventional neural recording systems restrict behavioral experiments to a flat indoor environment compatible with the cable that tethers the subject to recording instruments. To overcome these constraints, we developed a wireless multi-channel system for recording neural signals from rats. The device takes up to 64 voltage signals from implanted electrodes, samples each at 20 kHz, time-division multiplexes them into one signal and transmits that output by radio frequency to a receiver up to 60 m away. The system introduces <4 μV of electrode-referred noise, comparable to wired recording systems, and outperforms existing rodent telemetry systems in channel count, weight and transmission range. This allows effective recording of brain signals in freely behaving animals. We report measurements of neural population activity taken outdoors and in tunnels. Neural firing in the visual cortex was relatively sparse, correlated even across large distances and was strongly influenced by locomotor activity.

  10. The multi-channel laser focusing transceiver system and analysis of the image quality

    NASA Astrophysics Data System (ADS)

    Sui, Xin; Sun, Hongri; Yang, Kun; Qu, Zhou; Zhang, Bo; Cui, Yihan

    2015-10-01

    This paper has investigated and designed a multi-channel laser focusing transceiver system based on the combination of the laser technology, the space technology and the modern photoelectric detection technology which has the feather of wide wave band, non-chromatic aberration and high quality of image quality etc. The system could be synchronized and can change the distance of detection in a particular direction and obtain the image of atmospheric echo signals at different distances. In this paper we established a multi-channel and variable range laser focusing transceiver system that consists of a single-channel laser focusing transmitter system and a dual-channel receiving telescope system. The three channels of the system depend on the same reference axis. We propose a new method that is capable to improve the laser focusing transceiver system performance. The method is implemented by using parabolic reflector design in the primary and secondary mirror of the variable range laser focusing transmitter system, dual-channel off-axis design in the receiver system and simultaneous imaging design in the different regions of the same CCD target surface of the subsequent imaging system. The detection by two channels using off-axis design would be convenient for computing follow up information. On the base of theoretical basis of the reflective double mirror system and the theory Gaussian beam propagation, this paper calculates the actual converging sot size of the transmitter system and analyzes the wavefront aberration the defocus incidence. The oblique incidence will introduce the certain astigmatism and a small amount of coma and the defocus incidence will produce the certain coma and a small amount of spherical aberration and astigmatism. Finally, an experimental multi-channel laser focusing transceiver system was established and the image quality of the transceiver system on the base of wavefront aberrations, the spot diagram and the MTF curve of some fields is

  11. Estimation of black carbon content for biomass burning aerosols from multi-channel Raman lidar data

    NASA Astrophysics Data System (ADS)

    Talianu, Camelia; Marmureanu, Luminita; Nicolae, Doina

    2015-04-01

    Biomass burning due to natural processes (forest fires) or anthropical activities (agriculture, thermal power stations, domestic heating) is an important source of aerosols with a high content of carbon components (black carbon and organic carbon). Multi-channel Raman lidars provide information on the spectral dependence of the backscatter and extinction coefficients, embedding information on the black carbon content. Aerosols with a high content of black carbon have large extinction coefficients and small backscatter coefficients (strong absorption), while aerosols with high content of organic carbon have large backscatter coefficients (weak absorption). This paper presents a method based on radiative calculations to estimate the black carbon content of biomass burning aerosols from 3b+2a+1d lidar signals. Data is collected at Magurele, Romania, at the cross-road of air masses coming from Ukraine, Russia and Greece, where burning events are frequent during both cold and hot seasons. Aerosols are transported in the free troposphere, generally in the 2-4 km altitude range, and reaches the lidar location after 2-3 days. Optical data are collected between 2011-2012 by a multi-channel Raman lidar and follows the quality assurance program of EARLINET. Radiative calculations are made with libRadTran, an open source radiative model developed by ESA. Validation of the retrievals is made by comparison to a co-located C-ToF Aerosol Mass Spectrometer. Keywords: Lidar, aerosols, biomass burning, radiative model, black carbon Acknowledgment: This work has been supported by grants of the Romanian National Authority for Scientific Research, Programme for Research- Space Technology and Advanced Research - STAR, project no. 39/2012 - SIAFIM, and by Romanian Partnerships in priority areas PNII implemented with MEN-UEFISCDI support, project no. 309/2014 - MOBBE

  12. Multi-channel wireless mapping of gastrointestinal serosal slow wave propagation

    PubMed Central

    Paskaranandavadivel, Niranchan; Wang, Rui; Sathar, Shameer; O’Grady, Gregory; Cheng, Leo K; Farajidavar, Aydin

    2015-01-01

    Background High-resolution (HR) extracellular mapping allows accurate profiling of normal and dysrhythmic slow wave patterns. A current limitation is that cables traverse the abdominal wall or a natural orifice, risking discomfort, dislodgement or infection. Wireless approaches offer advantages, but a multi-channel system is required, capable of recording slow waves and mapping propagation with high fidelity. Methods A novel multi-channel (n=7) wireless mapping system was developed and compared to a wired commercial system. Slow wave signals were recorded from the porcine gastric and intestinal serosa in-vivo. Signals were simultaneously acquired using both systems, and were filtered and processed to map activation wavefronts. For validation, the frequency and amplitude of detected events were compared, together with the speed and direction of mapped wavefronts. Key Results The wireless device achieved comparable signal quality to the reference device, and slow wave frequencies were identical. Amplitudes of the acquired gastric and intestinal slow wave signals were consistent between the devices. During normal propagation, spatiotemporal mapping remained accurate in the wireless system, however, during ectopic dysrhythmic pacemaking, the lower sampling resolution of the wireless device led to reduced accuracy in spatiotemporal mapping. Conclusions and Inferences A novel multichannel wireless device is presented for mapping slow wave activity. The device achieved high quality signals, and has the potential to facilitate chronic monitoring studies and clinical translation of spatiotemporal mapping. The current implementation may be applied to detect normal patterns and dysrhythmia onset, but HR mapping with finely spaced arrays currently remains necessary to accurately define dysrhythmic patterns. PMID:25599978

  13. Joint Reconstruction of Multi-channel, Spectral CT Data via Constrained Total Nuclear Variation Minimization

    PubMed Central

    La Rivière, Patrick J.

    2015-01-01

    We explore the use of the recently proposed “total nuclear variation” (TVN) as a regularizer for reconstructing multi-channel, spectral CT images. This convex penalty is a natural extension of the total variation (TV) to vector-valued images and has the advantage of encouraging common edge locations and a shared gradient direction among image channels. We show how it can be incorporated into a general, data-constrained reconstruction framework and derive update equations based on the first-order, primal-dual algorithm of Chambolle and Pock. Early simulation studies based on the numerical XCAT phantom indicate that the inter-channel coupling introduced by the TVN leads to better preservation of image features at high levels of regularization, compared to independent, channel-by-channel TV reconstructions. PMID:25658985

  14. Self-aligned multi-channel silicon nanowire field-effect transistors

    NASA Astrophysics Data System (ADS)

    Zhu, Hao; Li, Qiliang; Yuan, Hui; Baumgart, Helmut; Ioannou, Dimitris E.; Richter, Curt A.

    2012-12-01

    Si nanowire field effect transistors (SiNW FETs) with multiple nanowire channels and different gate lengths have been fabricated by using a directed assembly approach combined with a standard photolithographic process. The electrical characteristics of SiNW FETs containing different numbers of nanowire channels were measured and compared. The multi-channel SiNW FETs show excellent performance: small subthreshold slope (≈75 mV/dec), large ON/OFF ratio (≈108), good break-down voltage (>30 V) and good carrier mobility (μp ≈ 100 cm2 V-1s-1). These excellent device properties were achieved by using a clean self-alignment process and an improved device structure with Schottky barriers at the source and drain contacts. Such high-performance multi-nanowire FETs are attractive for logic, memory, and sensor applications.

  15. Biomimetic Micropatterned Multi-channel Nerve Guides by Templated Electrospinning

    PubMed Central

    Jeffries, Eric; Wang, Yadong

    2012-01-01

    This report describes a new approach for fabricating micro-channels within three-dimensional electrospun constructs. These key features serve to mimic the fascicular architecture and fibrous extracellular matrix found in native nerve. Both electrospun fibers and multi-channeled structure nerve guides have become areas of increasing interest for their beneficial roles in nerve repair. However, to the best of our knowledge, this is the first report of a guide that incorporates both. Multiple parallel channels provide a greater number of defined paths and increased surface area compared to cylindrical guides. Additionally, the fibrous nature of electrospun fibers permits better mass transport than solid-walled constructs. The flexible fabrication scheme allows tailoring of nerve guide parameters such as channel diameters ranging from 33-176μm and various wall thicknesses. Channel and fiber structures were assessed by optical and electron microscope images. Geometric calculations estimated a porosity of over 85% for these guides with 16% or less from the channels. In vitro culture with Schwann cells demonstrated cellular infiltration into channels with restricted migration between fibers. Finally, cell proliferation and survival throughout the guide indicates that this design warrants future in vivo examination. PMID:22179932

  16. Local Spectral Component Decomposition for Multi-Channel Image Denoising.

    PubMed

    Rizkinia, Mia; Baba, Tatsuya; Shirai, Keiichiro; Okuda, Masahiro

    2016-07-01

    We propose a method for local spectral component decomposition based on the line feature of local distribution. Our aim is to reduce noise on multi-channel images by exploiting the linear correlation in the spectral domain of a local region. We first calculate a linear feature over the spectral components of an M -channel image, which we call the spectral line, and then, using the line, we decompose the image into three components: a single M -channel image and two gray-scale images. By virtue of the decomposition, the noise is concentrated on the two images, and thus our algorithm needs to denoise only the two gray-scale images, regardless of the number of the channels. As a result, image deterioration due to the imbalance of the spectral component correlation can be avoided. The experiment shows that our method improves image quality with less deterioration while preserving vivid contrast. Our method is especially effective for hyperspectral images. The experimental results demonstrate that our proposed method can compete with the other state-of-the-art denoising methods.

  17. A Wearable Multi-Channel fNIRS System for Brain Imaging in Freely Moving Subjects

    PubMed Central

    Piper, Sophie K.; Krueger, Arne; Koch, Stefan P.; Mehnert, Jan; Habermehl, Christina; Steinbrink, Jens; Obrig, Hellmuth; Schmitz, Christoph H.

    2013-01-01

    Functional near infrared spectroscopy (fNIRS) is a versatile neuroimaging tool with an increasing acceptance in the neuroimaging community. While often lauded for its portability, most of the fNIRS setups employed in neuroscientific research still impose usage in a laboratory environment. We present a wearable, multi-channel fNIRS imaging system for functional brain imaging in unrestrained settings. The system operates without optical fiber bundles, using eight dual wavelength light emitting diodes and eight electro-optical sensors, which can be placed freely on the subject's head for direct illumination and detection. Its performance is tested on N = 8 subjects in a motor execution paradigm performed under three different exercising conditions: (i) during outdoor bicycle riding, (ii) while pedaling on a stationary training bicycle, and (iii) sitting still on the training bicycle. Following left hand gripping, we observe a significant decrease in the deoxyhemoglobin concentration over the contralateral motor cortex in all three conditions. A significant task-related ΔHbO2 increase was seen for the non-pedaling condition. Although the gross movements involved in pedaling and steering a bike induced more motion artifacts than carrying out the same task while sitting still, we found no significant differences in the shape or amplitude of the HbR time courses for outdoor or indoor cycling and sitting still. We demonstrate the general feasibility of using wearable multi-channel NIRS during strenuous exercise in natural, unrestrained settings and discuss the origins and effects of data artifacts. We provide quantitative guidelines for taking condition-dependent signal quality into account to allow the comparison of data across various levels of physical exercise. To the best of our knowledge, this is the first demonstration of functional NIRS brain imaging during an outdoor activity in a real life situation in humans. PMID:23810973

  18. A wearable multi-channel fNIRS system for brain imaging in freely moving subjects.

    PubMed

    Piper, Sophie K; Krueger, Arne; Koch, Stefan P; Mehnert, Jan; Habermehl, Christina; Steinbrink, Jens; Obrig, Hellmuth; Schmitz, Christoph H

    2014-01-15

    Functional near infrared spectroscopy (fNIRS) is a versatile neuroimaging tool with an increasing acceptance in the neuroimaging community. While often lauded for its portability, most of the fNIRS setups employed in neuroscientific research still impose usage in a laboratory environment. We present a wearable, multi-channel fNIRS imaging system for functional brain imaging in unrestrained settings. The system operates without optical fiber bundles, using eight dual wavelength light emitting diodes and eight electro-optical sensors, which can be placed freely on the subject's head for direct illumination and detection. Its performance is tested on N=8 subjects in a motor execution paradigm performed under three different exercising conditions: (i) during outdoor bicycle riding, (ii) while pedaling on a stationary training bicycle, and (iii) sitting still on the training bicycle. Following left hand gripping, we observe a significant decrease in the deoxyhemoglobin concentration over the contralateral motor cortex in all three conditions. A significant task-related ΔHbO2 increase was seen for the non-pedaling condition. Although the gross movements involved in pedaling and steering a bike induced more motion artifacts than carrying out the same task while sitting still, we found no significant differences in the shape or amplitude of the HbR time courses for outdoor or indoor cycling and sitting still. We demonstrate the general feasibility of using wearable multi-channel NIRS during strenuous exercise in natural, unrestrained settings and discuss the origins and effects of data artifacts. We provide quantitative guidelines for taking condition-dependent signal quality into account to allow the comparison of data across various levels of physical exercise. To the best of our knowledge, this is the first demonstration of functional NIRS brain imaging during an outdoor activity in a real life situation in humans.

  19. Automated mitosis detection in histopathology using morphological and multi-channel statistics features

    PubMed Central

    Irshad, Humayun

    2013-01-01

    Context: According to Nottingham grading system, mitosis count plays a critical role in cancer diagnosis and grading. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader variations. Aims: The aim is to improve the accuracy of mitosis detection by selecting the color channels that better capture the statistical and morphological features, which classify mitosis from other objects. Materials and Methods: We propose a framework that includes comprehensive analysis of statistics and morphological features in selected channels of various color spaces that assist pathologists in mitosis detection. In candidate detection phase, we perform Laplacian of Gaussian, thresholding, morphology and active contour model on blue-ratio image to detect and segment candidates. In candidate classification phase, we extract a total of 143 features including morphological, first order and second order (texture) statistics features for each candidate in selected channels and finally classify using decision tree classifier. Results and Discussion: The proposed method has been evaluated on Mitosis Detection in Breast Cancer Histological Images (MITOS) dataset provided for an International Conference on Pattern Recognition 2012 contest and achieved 74% and 71% detection rate, 70% and 56% precision and 72% and 63% F-Measure on Aperio and Hamamatsu images, respectively. Conclusions and Future Work: The proposed multi-channel features computation scheme uses fixed image scale and extracts nuclei features in selected channels of various color spaces. This simple but robust model has proven to be highly efficient in capturing multi-channels statistical features for mitosis detection, during the MITOS international benchmark. Indeed, the mitosis detection of critical importance in cancer diagnosis is a very challenging visual task. In future work, we plan to use color deconvolution as preprocessing and Hough transform or local extrema based candidate detection

  20. Automated mitosis detection in histopathology using morphological and multi-channel statistics features.

    PubMed

    Irshad, Humayun

    2013-01-01

    According to Nottingham grading system, mitosis count plays a critical role in cancer diagnosis and grading. Manual counting of mitosis is tedious and subject to considerable inter- and intra-reader variations. The aim is to improve the accuracy of mitosis detection by selecting the color channels that better capture the statistical and morphological features, which classify mitosis from other objects. We propose a framework that includes comprehensive analysis of statistics and morphological features in selected channels of various color spaces that assist pathologists in mitosis detection. In candidate detection phase, we perform Laplacian of Gaussian, thresholding, morphology and active contour model on blue-ratio image to detect and segment candidates. In candidate classification phase, we extract a total of 143 features including morphological, first order and second order (texture) statistics features for each candidate in selected channels and finally classify using decision tree classifier. The proposed method has been evaluated on Mitosis Detection in Breast Cancer Histological Images (MITOS) dataset provided for an International Conference on Pattern Recognition 2012 contest and achieved 74% and 71% detection rate, 70% and 56% precision and 72% and 63% F-Measure on Aperio and Hamamatsu images, respectively. The proposed multi-channel features computation scheme uses fixed image scale and extracts nuclei features in selected channels of various color spaces. This simple but robust model has proven to be highly efficient in capturing multi-channels statistical features for mitosis detection, during the MITOS international benchmark. Indeed, the mitosis detection of critical importance in cancer diagnosis is a very challenging visual task. In future work, we plan to use color deconvolution as preprocessing and Hough transform or local extrema based candidate detection in order to reduce the number of candidates in mitosis and non-mitosis classes.

  1. Demonstration of a multi-channel, low-profile wire gauge for tracing wave development and detonation turning in explosives

    SciTech Connect

    Skidmore, Bradley E; Novak, Alan M; Zucker, Jonathan M; Parker, Jr, Gary R; Dickson, Peter; Foley, Timothy J; Trebs, Adam A

    2010-01-01

    The multi-channel low-profile wire gauge is a device which measures high pressure wave position via the continuous variation in length of a conductor in conjunction with a fiducial, allowing in situ measurement of wave front curvature during wave development. The gauge's low profile ({approx}250 {micro}m) and high resolution measurements (up to 0.5 nanoseconds) make it minimally intrusive and highly responsive, with a typically wave position accuracy of {+-}1 mm. Gauge construction and data analysis methods are described and waveforms are presented for Detasheet and N-9 explosives.

  2. Stacked, filtered multi-channel X-ray diode array

    SciTech Connect

    MacNeil, Lawrence; Dutra, Eric; Raphaelian, Mark; Compton, Steve; Jacoby, Barry

    2015-08-01

    There are many types of X-ray diodes used for X-ray flux or spectroscopic measurements and for estimating the spectral shape of the VUV to soft X-ray spectrum. However, a need exists for a low-cost, robust X-ray diode to use for experiments in hostile environments on multiple platforms, and for experiments that utilize forces that may destroy the diode(s). Since the typical proposed use required a small size with a minimal single line-of-sight, a parallel array could not be used. So, a stacked, filtered multi-channel X-ray diode array was developed, called the MiniXRD. To achieve significant cost savings while maintaining robustness and ease of field setup, repair, and replacement, we designed the system to be modular. The filters were manufactured in-house and cover the range from 450 eV to 5000 eV. To achieve the line-of-sight accuracy needed, we developed mounts and laser alignment techniques. We modeled and tested elements of the diode design at NSTec Livermore Operations (NSTec / LO) to determine temporal response and dynamic range, leading to diode shape and circuitry changes to optimize impedance and charge storage. The authors fielded individual and stacked systems at several national facilities as ancillary "ride-along" diagnostics to test and improve the design usability. This paper presents the MiniXRD system performance, which supports consideration as a viable low-costalternative for multiple-channel low-energy X-ray measurements. This diode array is currently at Technical Readiness Level (TRL) 6.

  3. Stacked, filtered multi-channel X-ray diode array

    NASA Astrophysics Data System (ADS)

    MacNeil, L. P.; Dutra, E. C.; Compton, S. M.; Jacoby, B. A.; Raphaelian, M. L.

    2015-08-01

    There are many types of X-ray diodes that are used for X-ray flux or spectroscopic measurements and for estimating the spectral shape of the VUV to soft X-ray spectrum. However, a need arose for a low cost, robust X-ray diode to use for experiments in hostile environments on multiple platforms, and for experiments that utilize forces that may destroy the diode(s). Since the typical proposed use required a small size with a minimal single line-of-sight, a parallel array could not be used. So, a stacked, filtered multi-channel X-ray diode array was developed, called the MiniXRD. To achieve significant cost savings while maintaining robustness and ease of field setup, repair, and replacement, we designed the system to be modular. The filters were manufactured in-house and cover the range from 450 eV to 5000 eV. To achieve the line-of-sight accuracy needed, we developed mounts and laser alignment techniques. We modeled and tested elements of the diode design at NSTec Livermore Operations (NSTec / LO) to determine temporal response and dynamic range, leading to diode shape and circuitry changes to optimize impedance and charge storage. We fielded individual and stacked systems at several national facilities as ancillary `ride-along' diagnostics to test and improve the design usability. We present the MiniXRD system performance which supports consideration as a viable low-cost alternative for multiple-channel low-energy X-ray measurements. This diode array is currently at Technical Readiness Level (TRL) 6.

  4. Solving non-Markovian open quantum systems with multi-channel reservoir coupling

    NASA Astrophysics Data System (ADS)

    Broadbent, Curtis J.; Jing, Jun; Yu, Ting; Eberly, Joseph H.

    2012-08-01

    We extend the non-Markovian quantum state diffusion (QSD) equation to open quantum systems which exhibit multi-channel coupling to a harmonic oscillator reservoir. Open quantum systems which have multi-channel reservoir coupling are those in which canonical transformation of reservoir modes cannot reduce the number of reservoir operators appearing in the interaction Hamiltonian to one. We show that the non-Markovian QSD equation for multi-channel reservoir coupling can, in some cases, lead to an exact master equation which we derive. We then derive the exact master equation for the three-level system in a vee-type configuration which has multi-channel reservoir coupling and give the analytical solution. Finally, we examine the evolution of the three-level vee-type system with generalized Ornstein-Uhlenbeck reservoir correlations numerically.

  5. EDMC: An enhanced distributed multi-channel anti-collision algorithm for RFID reader system

    NASA Astrophysics Data System (ADS)

    Zhang, YuJing; Cui, Yinghua

    2017-05-01

    In this paper, we proposes an enhanced distributed multi-channel reader anti-collision algorithm for RFID environments which is based on the distributed multi-channel reader anti-collision algorithm for RFID environments (called DiMCA). We proposes a monitor method to decide whether reader receive the latest control news after it selected the data channel. The simulation result shows that it improves interrogation delay.

  6. Refocusing capabilities in a miniaturized multi-channel multi-resolution imaging system using a tunable lens

    NASA Astrophysics Data System (ADS)

    Smeesters, L.; Belay, Gebirie Y.; Ottevaere, H.; Meuret, Youri; Thienpont, H.

    2014-05-01

    Inspired by nature, many application domains might gain from combining the multi-channel design of the compound eyes of insects and the refocusing capability of the human eye in one compact configuration. Multi-channel refocusing imaging systems are nowadays only commercially available in bulky and expensive designs since classical refocusing mechanisms cannot be integrated in a miniaturized configuration. We designed a wafer-level multi-resolution two-channel imaging system with refocusing capabilities using a voltage tunable liquid lens. One channel is able to capture a wide field-of-view image (2x40°) of a surrounding with a low angular resolution (0.078°), whereas a detailed image of a small region of interest (2x7.57°) can be obtained with the high angular resolution channel (0.0098°). The latter high angular resolution channel contains the tunable lens and therefore also the refocusing capabilities. In this paper, we first discuss the working principle, tunability and optical quality of a voltage tunable liquid lens. Based on optical characterization measurements with a Mach-Zehnder interferometer, we designed a tunable lens model. The designed tunable lens model and its validation in an imaging setup show a diffraction-limited image quality. Following, we discuss the performance of the designed two-channel imaging system. Both the wide field-of-view and high angular resolution optical channels show a diffraction-limited performance, ensuring a good image quality. Moreover, we obtained an improved depth-of-field, from 0.254m until infinity, in comparison with the current state-of-the art published wafer-level multi-channel imaging systems, which show a depth-of-field from 9m until infinity.

  7. A new RF trench-gate multi-channel laterally-diffused MOSFET on InGaAs

    NASA Astrophysics Data System (ADS)

    Payal, M.; Singh, Y.

    2017-09-01

    In this work, a new RF power trench-gate multi-channel laterally-diffused MOSFET (TGMC-LDMOS) on InGaAs is proposed. The gate-electrodes of the new structure are placed vertically in the trenches built in the drift layer. Each gate results in the formation of two channels in the p-body region of the device. The drain metal is also placed in a trench to take contact from the n+-InGaAs region located over the substrate. In a cell length of 5 {{μ }}{{m}}, the TGMC-LDMOS structure has seven channels, which conduct simultaneously to carry drain current in parallel. The formation of multi-channels in the proposed device increases the drive current ({I}{{D}}) leading to a large reduction in the specific on-resistance ({R}{{on-sp}}). Due to better control of gates on the drain current, the new structure exhibits substantially higher transconductance ({g}{{m}}) resulting in significant improvement in cut-off frequency ({f}{{T}}) and oscillation frequency ({f}\\max ). Using two-dimensional numerical simulations, a 55 V TGMC-LDMOS is demonstrated to achieve 7 times higher {I}{{D}}, 6.2 times lower {R}{{on-sp}}, 6.3 times higher peak {g}{{m}}, 2.6 times higher {f}{{T}}, and 2.5 times increase in {f}\\max in comparison to a conventional device for the identical cell length.

  8. Multi-channel beam-scanning imaging at kHz frame rates by Lissajous trajectory microscopy

    PubMed Central

    Newman, Justin A.; Sullivan, Shane Z.; Muir, Ryan D.; Sreehari, Suhas; Bouman, Charles A.; Simpson, Garth J.

    2016-01-01

    A beam-scanning microscope based on Lissajous trajectory imaging is described for achieving streaming 2D imaging with continuous frame rates up to 1.4 kHz. The microscope utilizes two fast-scan resonant mirrors to direct the optical beam on a circuitous trajectory through the field of view. By separating the full Lissajous trajectory time-domain data into sub-trajectories (partial, undersampled trajectories) effective frame-rates much higher than the repeat time of the Lissajous trajectory are achieved with many unsampled pixels present. A model-based image reconstruction (MBIR) 3D in-painting algorithm is then used to interpolate the missing data for the unsampled pixels to recover full images. The MBIR algorithm uses a maximum a posteriori estimation with a generalized Gaussian Markov random field prior model for image interpolation. Because images are acquired using photomultiplier tubes or photodiodes, parallelization for multi-channel imaging is straightforward. Preliminary results show that when combined with the MBIR in-painting algorithm, this technique has the ability to generate kHz frame rate images across 6 total dimensions of space, time, and polarization for SHG, TPEF, and confocal reflective birefringence data on a multimodal imaging platform for biomedical imaging. The use of a multi-channel data acquisition card allows for multimodal imaging with perfect image overlay. Image blur due to sample motion was also reduced by using higher frame rates. PMID:27041787

  9. Multi-channel beam-scanning imaging at kHz frame rates by Lissajous trajectory microscopy.

    PubMed

    Newman, Justin A; Sullivan, Shane Z; Muir, Ryan D; Sreehari, Suhas; Bouman, Charles A; Simpson, Garth J

    2015-03-09

    A beam-scanning microscope based on Lissajous trajectory imaging is described for achieving streaming 2D imaging with continuous frame rates up to 1.4 kHz. The microscope utilizes two fast-scan resonant mirrors to direct the optical beam on a circuitous trajectory through the field of view. By separating the full Lissajous trajectory time-domain data into sub-trajectories (partial, undersampled trajectories) effective frame-rates much higher than the repeat time of the Lissajous trajectory are achieved with many unsampled pixels present. A model-based image reconstruction (MBIR) 3D in-painting algorithm is then used to interpolate the missing data for the unsampled pixels to recover full images. The MBIR algorithm uses a maximum a posteriori estimation with a generalized Gaussian Markov random field prior model for image interpolation. Because images are acquired using photomultiplier tubes or photodiodes, parallelization for multi-channel imaging is straightforward. Preliminary results show that when combined with the MBIR in-painting algorithm, this technique has the ability to generate kHz frame rate images across 6 total dimensions of space, time, and polarization for SHG, TPEF, and confocal reflective birefringence data on a multimodal imaging platform for biomedical imaging. The use of a multi-channel data acquisition card allows for multimodal imaging with perfect image overlay. Image blur due to sample motion was also reduced by using higher frame rates.

  10. Application of multi-channel photoelastic imaging technology in array type ultrasonic nondestructive testing

    NASA Astrophysics Data System (ADS)

    Fan, Zhen-zhong; Bi, Chao

    2015-08-01

    With the rapid development of modern nondestructive testing technologies, ultrasonic phased array and Ultrasonic array testing technology has been used widely, at the same time the propagation process of ultrasonic in the material becomes more and more complex. In order to make the ultrasonic propagation path become visible and researchers can observe the acoustic field directly, considering the properties of the ultrasonic as a stress wave, according to the theory of polarized light interference, a multi-channel dynamic photoelastic imaging system is developed successfully. The system can generate many kinds of focusing ultrasonic fields in optical specimen by controlling the ultrasonic transmission delay time of each equipment channel, and the system has the ability to simulate the acoustic field's focusing process of the ultrasonic phased array. The image shot by CCD camera reflects the propagation process of the acoustic field in the specimen, and the dynamic video is formed under control of the timing circuit, and the system has the ability to save the captured image in the computer.

  11. Design and implementation of the parallel processing system of multi-channel polarization images

    NASA Astrophysics Data System (ADS)

    Li, Zhi-yong; Huang, Qin-chao

    2013-08-01

    Compared with traditional optical intensity image processing, polarization images processing has two main problems. One is that the amount of data is larger. The other is that processing tasks is more complex. To resolve these problems, the parallel processing system of multi-channel polarization images is designed by the multi-DSP technique. It contains a communication control unit (CCU) and a data processing array (DPA). CCU controls communications inside and outside the system. Its logics are designed by a FPGA chip. DPA is made up of four Digital Signal Processor (DSP) chips, which are interlinked by the loose coupling method. DPA implements processing tasks including images registration and images synthesis by parallel processing methods. The polarization images parallel processing model is designed on multi levels including the system task, the algorithm and the operation. Its program is designed by the assemble language. While the polarization image resolution is 782x582 pixels, the pixel data length is 12 bits in the experiment. After it received 3 channels of polarization image simultaneously, this system implements parallel task to acquire the target polarization characteristics. Experimental results show that this system has good real-time and reliability. The processing time of images registration is 293.343ms while the registration accuracy achieves 0.5 pixel. The processing time of images synthesis is 3.199ms.

  12. A CAMAC-based multi-channel digital delay generator for TACTIC gamma-ray telescope

    NASA Astrophysics Data System (ADS)

    Kaul, S. R.; Yadav, K. K.; Tickoo, A. K.; Koul, R.

    A programmable multi-channel CAMAC-based Digital Delay Generator (DDG) having a full scale delay of sim256ns and a resolution of sim 1ns has been developed for the TACTIC gamma-ray telescope array. The TACTIC telescope array comprises 4 times 10 m^2 altitude-azimuth mounted tracking light collectors arranged in a manner so that they represent the centre and three vertices of an equilateral triangle of side 20 m. The central element deploys a 349-pixel imaging camera and is referred to as the IMAGING Element (IE) while the three elements located at the vertices deploy low resolution 16 pixel cameras and are referred to as VERTEX Elements (VE). The function of the DDG is to achieve time synchronization between the trigger pulse from the IE and the 3 VE photomultiplier outputs so that the charge content of their respective 16 detector channels can be faithfully recorded. The unequal signal propagation time between the telescope elements arises because of their physical separation and the relative delay between them depends upon the pointing direction of the source which is being tracked by all the 4 telescope elements simultaneously. The design details of the DDG module (based on AD9500 IC) along with the edure for implementing the delays in the 3 VEs as a function of the source hour angle will be presented here.

  13. A Multi-Channel, Flex-Rigid ECoG Microelectrode Array for Visual Cortical Interfacing

    PubMed Central

    Tolstosheeva, Elena; Gordillo-González, Víctor; Biefeld, Volker; Kempen, Ludger; Mandon, Sunita; Kreiter, Andreas K.; Lang, Walter

    2015-01-01

    High-density electrocortical (ECoG) microelectrode arrays are promising signal-acquisition platforms for brain-computer interfaces envisioned, e.g., as high-performance communication solutions for paralyzed persons. We propose a multi-channel microelectrode array capable of recording ECoG field potentials with high spatial resolution. The proposed array is of a 150 mm2 total recording area; it has 124 circular electrodes (100, 300 and 500 μm in diameter) situated on the edges of concentric hexagons (min. 0.8 mm interdistance) and a skull-facing reference electrode (2.5 mm2 surface area). The array is processed as a free-standing device to enable monolithic integration of a rigid interposer, designed for soldering of fine-pitch SMD-connectors on a minimal assembly area. Electrochemical characterization revealed distinct impedance spectral bands for the 100, 300 and 500 μm-type electrodes, and for the array's own reference. Epidural recordings from the primary visual cortex (V1) of an awake Rhesus macaque showed natural electrophysiological signals and clear responses to standard visual stimulation. The ECoG electrodes of larger surface area recorded signals with greater spectral power in the gamma band, while the skull-facing reference electrode provided higher average gamma power spectral density (γPSD) than the common average referencing technique. PMID:25569757

  14. Multi-channel purge and trap system coupled with ion chromatography for the determination of alkylamines in cosmetics.

    PubMed

    Zhong, Zhixiong; Li, Gongke; Luo, Zhibin; Zhu, Binghui

    2012-02-17

    A new multi-channel purge and trap system coupled with ion chromatography for the determination of six alkylamines in cosmetics was developed. The proposed method, based on purge and trap of the volatile alkylamines, involved in a miniaturization and multi-channel integration of classical steam distillation and a simple approach for routine labs. The procedure was rapidly achieved within 10 min and the matrix interferences could be effectively eliminated. Sample pretreatment frequency was higher than 40 h(-1). The linear ranges were 0.1-15 mg L(-1) and the detection limits varied from 0.023 to 0.038 mg L(-1). This method was successfully utilized to determine the amounts of alkylamines in cosmetics with recoveries ranging from 80.3 to 105.5% and the relative standard deviations (RSDs) ranging from 0.78 to 7.5%. It was proved to be accurate, time-saving, and suitable for the determination of large numbers of cosmetics in a short time.

  15. Synchronous acquisition of multi-channel signals by single-channel ADC based on square wave modulation.

    PubMed

    Yi, Xiaoqing; Hao, Liling; Jiang, Fangfang; Xu, Lisheng; Song, Shaoxiu; Li, Gang; Lin, Ling

    2017-08-01

    Synchronous acquisition of multi-channel biopotential signals, such as electrocardiograph (ECG) and electroencephalograph, has vital significance in health care and clinical diagnosis. In this paper, we proposed a new method which is using single channel ADC to acquire multi-channel biopotential signals modulated by square waves synchronously. In this method, a specific modulate and demodulate method has been investigated without complex signal processing schemes. For each channel, the sampling rate would not decline with the increase of the number of signal channels. More specifically, the signal-to-noise ratio of each channel is n times of the time-division method or an improvement of 3.01×log2n dB, where n represents the number of the signal channels. A numerical simulation shows the feasibility and validity of this method. Besides, a newly developed 8-lead ECG based on the new method has been introduced. These experiments illustrate that the method is practicable and thus is potential for low-cost medical monitors.

  16. Synchronous acquisition of multi-channel signals by single-channel ADC based on square wave modulation

    NASA Astrophysics Data System (ADS)

    Yi, Xiaoqing; Hao, Liling; Jiang, Fangfang; Xu, Lisheng; Song, Shaoxiu; Li, Gang; Lin, Ling

    2017-08-01

    Synchronous acquisition of multi-channel biopotential signals, such as electrocardiograph (ECG) and electroencephalograph, has vital significance in health care and clinical diagnosis. In this paper, we proposed a new method which is using single channel ADC to acquire multi-channel biopotential signals modulated by square waves synchronously. In this method, a specific modulate and demodulate method has been investigated without complex signal processing schemes. For each channel, the sampling rate would not decline with the increase of the number of signal channels. More specifically, the signal-to-noise ratio of each channel is n times of the time-division method or an improvement of 3.01 ×log2n dB, where n represents the number of the signal channels. A numerical simulation shows the feasibility and validity of this method. Besides, a newly developed 8-lead ECG based on the new method has been introduced. These experiments illustrate that the method is practicable and thus is potential for low-cost medical monitors.

  17. Automated Interval velocity picking for Atlantic Multi-Channel Seismic Data

    NASA Astrophysics Data System (ADS)

    Singh, Vishwajit

    2016-04-01

    This paper described the challenge in developing and testing a fully automated routine for measuring interval velocities from multi-channel seismic data. Various approaches are employed for generating an interactive algorithm picking interval velocity for continuous 1000-5000 normal moveout (NMO) corrected gather and replacing the interpreter's effort for manual picking the coherent reflections. The detailed steps and pitfalls for picking the interval velocities from seismic reflection time measurements are describe in these approaches. Key ingredients these approaches utilized for velocity analysis stage are semblance grid and starting model of interval velocity. Basin-Hopping optimization is employed for convergence of the misfit function toward local minima. SLiding-Overlapping Window (SLOW) algorithm are designed to mitigate the non-linearity and ill- possessedness of root-mean-square velocity. Synthetic data case studies addresses the performance of the velocity picker generating models perfectly fitting the semblance peaks. A similar linear relationship between average depth and reflection time for synthetic model and estimated models proposed picked interval velocities as the starting model for the full waveform inversion to project more accurate velocity structure of the subsurface. The challenges can be categorized as (1) building accurate starting model for projecting more accurate velocity structure of the subsurface, (2) improving the computational cost of algorithm by pre-calculating semblance grid to make auto picking more feasible.

  18. Design Study of a Multi-channel Array Particle Spectrometer for Space Missions

    NASA Astrophysics Data System (ADS)

    Trindade, Andreia; Assis, P.; Brogueira, P.; Gonçalves, P.; Keating, A.; Pimenta, M.; Rodrigues, P.; Trindade, A.

    In this work, a novel particle spectrometer is proposed to fulfil the need to map the space radiation environment for future space missions and to provide more accurate scientific data. The concept of the instrument brings together new radiation-hard technologies, for the photo-sensors and scintillating materials that will improve the quality of the data, while taking into account the limited resources such as mass, power and accommodation, allocated for space radiation monitors. The Multi-channel Array Particle Spectrometer (MAPS), can measure fluxes and energy dis-tributions of protons, ions, electrons and gammas in a wide energy range based on the 3D reconstruction of the particle track through the detector and its deposited energy in the active volume. It consists on a 8 x 8 segmented scintillator block built from 3.2 x 3.2 x 20 mm3 indi-vidual LYSO:Ce rods that are readout at both ends by two 64 pixel Silicon Photo-Multipliers (SiPMs) matrices, a new generation of high gain (105-106) avalanche photodiodes working in controlled Geiger mode, that collect the scintillating light produced by the interactions of the charged particles in the crystals. Each SiPM matrix is readout by a 64 channel mixed sig-nal analog-digital ASIC, offering both particle identification and particle counting capabilities. Power cycling design of the ASIC allows to activate the particle identification block only during a pre-determined time slice, keeping the total power budget of less than 1 mW/channel. An on-board FPGA sorts the serialized data from the two ASICs and computes the trigger primitives in real-time and in an event-by-event basis. Whenever a charged particle crosses the segmented volume of the detector, the XY coordinates, given by the pixelized crystal positions, and the deposited energy in each crystal is recorded. The double readout scheme allows to compute the light collection asymmetry between both ends of the crystal and to use that information to record the

  19. Long-distance multi-channel bidirectional chaos communication based on synchronized VCSELs subject to chaotic signal injection

    NASA Astrophysics Data System (ADS)

    Xie, Yi-Yuan; Li, Jia-Chao; He, Chao; Zhang, Zhen-Dong; Song, Ting-Ting; Xu, Chang-Jun; Wang, Gui-Jin

    2016-10-01

    A novel long-distance multi-channel bidirectional chaos communication system over multiple paths based on two synchronized 1550 nm vertical-cavity surface-emitting lasers (VCSELs) is proposed and studied theoretically. These two responding VCSELs (R-VCSELs) can output similar chaotic signals served as chaotic carrier in two linear polarization (LP) modes with identical signal injection from a driving VCSEL (D-VCSEL), which is subject to optical feedback and optical injection, simultaneously. Through the numerical simulations, high quality chaos synchronization between the two R-VCSELs can be obtained. Besides, the effects of varied qualities of chaos synchronization on communication performances in 20 km single mode fiber (SMF) channels are investigated by regulating different internal parameters mismatch after adopting chaos masking (CMS) technique. With the decrease of the maximum cross correlation coefficient (Max-C) between the two R-VCSELs, the bit error rate (BER) of decoded message increase. Meanwhile, the BER can still be less than 10-9 when the Max-C degrades to 0.982. Based on high quality synchronization, when the dispersion compensating fiber (DCF) links are introduced, 4n messages of 10 Gbit/s can transmit in 180 km SMF channels over n coupling paths, bidirectionally and simultaneously. Thorough tests are carried out with detailed analysis, demonstrating long-distance, multi-channel, bidirectional chaos communication based on VCSELs with chaotic signal injection.

  20. Accuracy and Precision of Head Motion Information in Multi-Channel Free Induction Decay Navigators for Magnetic Resonance Imaging.

    PubMed

    Babayeva, Maryna; Kober, Tobias; Knowles, Benjamin; Herbst, Michael; Meuli, Reto; Zaitsev, Maxim; Krueger, Gunnar

    2015-09-01

    Free induction decay (FID) navigators were found to qualitatively detect rigid-body head movements, yet it is unknown to what extent they can provide quantitative motion estimates. Here, we acquired FID navigators at different sampling rates and simultaneously measured head movements using a highly accurate optical motion tracking system. This strategy allowed us to estimate the accuracy and precision of FID navigators for quantification of rigid-body head movements. Five subjects were scanned with a 32-channel head coil array on a clinical 3T MR scanner during several resting and guided head movement periods. For each subject we trained a linear regression model based on FID navigator and optical motion tracking signals. FID-based motion model accuracy and precision was evaluated using cross-validation. FID-based prediction of rigid-body head motion was found to be with a mean translational and rotational error of 0.14±0.21 mm and 0.08±0.13°, respectively. Robust model training with sub-millimeter and sub-degree accuracy could be achieved using 100 data points with motion magnitudes of ±2 mm and ±1° for translation and rotation. The obtained linear models appeared to be subject-specific as inter-subject application of a "universal" FID-based motion model resulted in poor prediction accuracy. The results show that substantial rigid-body motion information is encoded in FID navigator signal time courses. Although, the applied method currently requires the simultaneous acquisition of FID signals and optical tracking data, the findings suggest that multi-channel FID navigators have a potential to complement existing tracking technologies for accurate rigid-body motion detection and correction in MRI.

  1. Non-local Atlas-guided Multi-channel Forest Learning for Human Brain Labeling

    PubMed Central

    Ma, Guangkai; Gao, Yaozong; Wu, Guorong; Wu, Ligang; Shen, Dinggang

    2015-01-01

    Labeling MR brain images into anatomically meaningful regions is important in many quantitative brain researches. In many existing label fusion methods, appearance information is widely used. Meanwhile, recent progress in computer vision suggests that the context feature is very useful in identifying an object from a complex scene. In light of this, we propose a novel learning-based label fusion method by using both low-level appearance features (computed from the target image) and high-level context features (computed from warped atlases or tentative labeling maps of the target image). In particular, we employ a multi-channel random forest to learn the nonlinear relationship between these hybrid features and the target labels (i.e., corresponding to certain anatomical structures). Moreover, to accommodate the high inter-subject variations, we further extend our learning-based label fusion to a multi-atlas scenario, i.e., we train a random forest for each atlas and then obtain the final labeling result according to the consensus of all atlases. We have comprehensively evaluated our method on both LONI-LBPA40 and IXI datasets, and achieved the highest labeling accuracy, compared to the state-of-the-art methods in the literature. PMID:26942235

  2. Ultra-Low Power Fast Multi-Channel 10-Bit ADC ASIC for Readout of Particle Physics Detectors

    NASA Astrophysics Data System (ADS)

    Bugiel, S.; Dasgupta, R.; Firlej, M.; Fiutowski, T.; Idzik, M.; Kopec, M.; Moron, J.; Swientek, K.

    2016-10-01

    The design and measurement results of an ultra-low power multi-channel fast 10-bit Analog-to-Digital Converter (ADC) ASIC, developed for readout systems in future particle physics experiments, are discussed. An 8-channel prototype with a PLL-based data serialization and a fast data transmission was designed and fabricated in a 130 nm CMOS process. The ADC converts analog data with sampling rates from about 10 kS/s to 40 MS/s, with power consumption proportional to sampling rate. The resulting Figure of Merit (FOM), for sampling rates 5-40 MS/s, is 35-42 fJ/conv.-step, per ADC channel. Similar power contribution is spent for fast data serialization and the largest contribution goes to data transmission. A wide spectrum of static and dynamic measurements confirm very good performance of this multi-channel ADC with ENOB 9.2 bits, an excellent channel uniformity, and negligible crosstalk. The ADC works asynchronously and so it is not limited to systems with uniform time sampling. The ADC is designed using dynamic circuitry which eliminates static power consumption (except leakage), as a consequence it is ready for applications requiring power cycling.

  3. Note: A high count rate real-time digital processing method for PGNAA data acquisition system.

    PubMed

    Liu, Yuzhe; Chen, Lian; Li, Feng; Liang, Futian; Jin, Ge

    2017-07-01

    The prompt gamma neutron activation analysis (PGNAA) technique is a real-time online method to analyze the composition of industrial materials. This paper presents a data acquisition system with a high count rate and real-time digital processing method for PGNAA. Limited by the decay time of the detector, the ORTEC multi-channel analyzer (MCA) can normally achieve an average count rate of 100 kcps. However, this system uses an electrical technique to increase the average count rate and reduce dead time, and guarantees good accuracy. Since the measuring time is usually limited to about 120 s, in order to accelerate the accumulation rate of spectrum and reduce the statistical error, the average count rate is expected to reach more than 500 kcps.

  4. Note: A high count rate real-time digital processing method for PGNAA data acquisition system

    NASA Astrophysics Data System (ADS)

    Liu, Yuzhe; Chen, Lian; Li, Feng; Liang, Futian; Jin, Ge

    2017-07-01

    The prompt gamma neutron activation analysis (PGNAA) technique is a real-time online method to analyze the composition of industrial materials. This paper presents a data acquisition system with a high count rate and real-time digital processing method for PGNAA. Limited by the decay time of the detector, the ORTEC multi-channel analyzer (MCA) can normally achieve an average count rate of 100 kcps. However, this system uses an electrical technique to increase the average count rate and reduce dead time, and guarantees good accuracy. Since the measuring time is usually limited to about 120 s, in order to accelerate the accumulation rate of spectrum and reduce the statistical error, the average count rate is expected to reach more than 500 kcps.

  5. Audio representations of multi-channel EEG: a new tool for diagnosis of brain disorders

    PubMed Central

    Vialatte, François B; Dauwels, Justin; Musha, Toshimitsu; Cichocki, Andrzej

    2012-01-01

    Objective: The objective of this paper is to develop audio representations of electroencephalographic (EEG) multichannel signals, useful for medical practitioners and neuroscientists. The fundamental question explored in this paper is whether clinically valuable information contained in the EEG, not available from the conventional graphical EEG representation, might become apparent through audio representations. Methods and Materials: Music scores are generated from sparse time-frequency maps of EEG signals. Specifically, EEG signals of patients with mild cognitive impairment (MCI) and (healthy) control subjects are considered. Statistical differences in the audio representations of MCI patients and control subjects are assessed through mathematical complexity indexes as well as a perception test; in the latter, participants try to distinguish between audio sequences from MCI patients and control subjects. Results: Several characteristics of the audio sequences, including sample entropy, number of notes, and synchrony, are significantly different in MCI patients and control subjects (Mann-Whitney p < 0.01). Moreover, the participants of the perception test were able to accurately classify the audio sequences (89% correctly classified). Conclusions: The proposed audio representation of multi-channel EEG signals helps to understand the complex structure of EEG. Promising results were obtained on a clinical EEG data set. PMID:23383399

  6. Audio representations of multi-channel EEG: a new tool for diagnosis of brain disorders.

    PubMed

    Vialatte, François B; Dauwels, Justin; Musha, Toshimitsu; Cichocki, Andrzej

    2012-01-01

    The objective of this paper is to develop audio representations of electroencephalographic (EEG) multichannel signals, useful for medical practitioners and neuroscientists. The fundamental question explored in this paper is whether clinically valuable information contained in the EEG, not available from the conventional graphical EEG representation, might become apparent through audio representations. Music scores are generated from sparse time-frequency maps of EEG signals. Specifically, EEG signals of patients with mild cognitive impairment (MCI) and (healthy) control subjects are considered. Statistical differences in the audio representations of MCI patients and control subjects are assessed through mathematical complexity indexes as well as a perception test; in the latter, participants try to distinguish between audio sequences from MCI patients and control subjects. Several characteristics of the audio sequences, including sample entropy, number of notes, and synchrony, are significantly different in MCI patients and control subjects (Mann-Whitney p < 0.01). Moreover, the participants of the perception test were able to accurately classify the audio sequences (89% correctly classified). The proposed audio representation of multi-channel EEG signals helps to understand the complex structure of EEG. Promising results were obtained on a clinical EEG data set.

  7. A Radiation Hard Multi-Channel Digitizer ASIC for Operation in the Harsh Jovian Environment

    NASA Technical Reports Server (NTRS)

    Aslam, Shahid; Aslam, S.; Akturk, A.; Quilligan, G.

    2011-01-01

    ultimately impact the surface of Europa after the mission is completed. The current JEO mission concept includes a range of instruments on the payload, to monitor dynamic phenomena (such as Io's volcanoes and Jupiters atmosphere), map the Jovian magnetosphere and its interactions with the Galilean satellites, and characterize water oceans beneath the ice shells of Europa and Ganymede. The payload includes a low mass (3.7 Kg) and low power (< 5 W) Thermal Instrument (TI) concept for measuring possible warm thermal anomalies on Europa s cold surface caused by recent (< 10,000 years) eruptive activity. Regions of anomalously high heat flow will be identified by thermal mapping using a nadir pointing, push-broom filter radiometer that provides far-IR imagery in two broad band spectral wavelength regions, 8-20 m and 20-100 m, for surface temperature measurements with better than a 2 K accuracy and a spatial resolution of 250 m/pixel obtained from a 100 Km orbit. The temperature accuracy permits a search for elevated temperatures when combined with albedo information. The spatial resolution is sufficient to resolve Europa's larger cracks and ridge axial valleys. In order to accomplish the thermal mapping, the TI uses sensitive thermopile arrays that are readout by a custom designed low-noise Multi-Channel Digitizer (MCD) ASIC that resides very close to the thermopile linear array outputs. Both the thermopile array and the MCD ASIC will need to show full functionality within the harsh Jovian radiation environment, operating at cryogenic temperatures, typically 150 K to 170 K. In the following, a radiation mitigation strategy together with a low risk Radiation-Hardened-By-Design (RHBD) methodology using commercial foundry processes is given for the design and manufacture of a MCD ASIC that will meet this challenge.

  8. Electrical properties of flexible multi-channel Si nanowire field-effect transistors depending on the number of Si nanowires.

    PubMed

    Kim, Do Hoon; Lee, Su Jeong; Lee, Sang Hoon; Myoung, Jae-Min

    2016-05-25

    Flexible multi-channel Si nanowire (NW) field-effect transistors (FETs) were investigated to determine the effect of the number of Si NWs. The Langmuir-Blodgett method was applied for the formation of well-aligned Si NW monolayers, and an ion-gel with a high dielectric constant was used as a gate insulator in a top-gate TFT structure to secure flexibility. Like typical nanoelectronic devices, the drain current changed with the number of Si NWs. However, unlike previous reports, the mobility of the multi-channel Si NW FETs increased from 42.8 to 124.6 cm(2) V(-1) s(-1) as the number of Si NWs was increased from 1 to 58. To verify the feasibility of our approach, the electrical performance of the TFTs fabricated on a flexible polyimide (PI) substrate was analyzed in respect of the bending strain (0.08-1.51%) and bending cycle (up to 12 000 cycles). As the number of Si NWs was increased, the trade-off between electrical and mechanical properties during bending tests was confirmed, and the appropriate number of Si NWs was optimized for a flexible FET with excellent performance.

  9. 802.11s based multi-radio multi-channel mesh networking for fractionated spacecraft

    NASA Astrophysics Data System (ADS)

    Michel, Tony; Thapa, Bishal; Taylor, Steve

    802.11s is a new IEEE standard for mesh networking. It defines the protocols needed to build mobile ad hoc networks that operate over 802.11a, b, g and n waveforms running on inexpensive, and high performance commercial WiFi stations. We have developed a new capability to add to the 802.11s that uses multiple directional radio links that can operate simultaneously within a single mesh node. This is the basis of our multi-channel multi-radio mesh network used in the DARPA F6 program called F6Net. We have developed an analysis and emulation facility that lets us model the F6Net and evaluate the performance in a real world experimentation setup. This paper presents an “ Over-the-Air” experimentation testbed that uses standard Commercial Off-The-Shelf (COTS) 2.4GHz WiFi dongles in an indoor environment, and a shared-code simulation testbed that uses hardware simulated drivers within NS3's channel simulation facility to test 80211s network. To the best of our knowledge, this is the first work that provides a comprehensive evaluation platform with a full-fledged COTS hardware/software prototype to evaluate 802.11s network. Furthermore, we explain the design and development of multi-radio mesh extension for 802.11s that yields a robust and scalable mesh network suitable for clusters of LEO satellites.

  10. Clinical application of DEX/CRH test and multi-channel NIRS in patients with depression.

    PubMed

    Kinoshita, Shinya; Kanazawa, Tetsufumi; Kikuyama, Hiroki; Yoneda, Hiroshi

    2016-08-31

    To reduce the number of patients with depression, biomarkers for clarifying psychiatric disorders are warranted. Numerous candidates have been proposed; however, near-infrared spectroscopy (NIRS) with multi-channel probes and a dexamethasone/corticotropin-releasing hormone (DEX/CRH) test are still surviving for practical demand. Thirty-one outpatients with depressed moods were analyzed using both biological tests. The non-suppressors, as indicated by the DEX/CRH test, exhibited a high severity on the Hamilton Depression Scale and severe anxiety on the State Trait Anxiety Scale. In addition, a unique response was identified via NIRS in the same group suggested by the DEX/CRH assessment. The results obtained from these biological tests did not fit well with the category defined by operative diagnostic criteria, such as the Diagnostic and Statistical Manual of Mental Disorders or The International Classification of Diseases. Thus, it is critical that the utility evaluations of candidate biomarkers not be assessed by comparisons with the categorized criteria for a specific psychiatric disorder. Trial registration UMIN000013214, Registered 21 February 2014.

  11. Salt Plug Formation Caused by Decreased River Discharge in a Multi-channel Estuary

    PubMed Central

    Shaha, Dinesh Chandra; Cho, Yang-Ki

    2016-01-01

    Freshwater input to estuaries may be greatly altered by the river barrages required to meet human needs for drinking water and irrigation and prevent salt water intrusion. Prior studies have examined the salt plugs associated with evaporation and salt outwelling from tidal salt flats in single-channel estuaries. In this work, we discovered a new type of salt plug formation in the multi-channel Pasur River Estuary (PRE) caused by decreasing river discharges resulting from an upstream barrage. The formation of a salt plug in response to changes in river discharge was investigated using a conductivity-temperature-depth (CTD) recorder during spring and neap tides in the dry and wet seasons in 2014. An exportation of saline water from the Shibsa River Estuary (SRE) to the PRE through the Chunkhuri Channel occurred during the dry season, and a salt plug was created and persisted from December to June near Chalna in the PRE. A discharge-induced, relatively high water level in the PRE during the wet season exerted hydrostatic pressure towards the SRE from the PRE and thereby prevented the intrusion of salt water from the SRE to the PRE. PMID:27255892

  12. Underwater target classification using the wing BOSS and multi-channel decision fusion

    NASA Astrophysics Data System (ADS)

    Wachowski, Neil; Azimi-Sadjadi, Mahmood R.; Cartmill, Jered

    2007-04-01

    In this paper, two different multi-aspect underwater target classification systems are evaluated based on their ability to correctly detect and classify mine-like objects. These methods are tested on a recently collected database that consists of sonar returns from various buried mine-like and non-mine-like objects in different operating and environmental conditions. In one approach, coherent features are extracted from the data using canonical correlation analysis (CCA) between two sonar pings. Classification is performed using a collaborative multi-aspect classifier (CMAC), which utilizes a group of collaborative decision-making agents capable of producing a high-confidence final decision based on these features. The second approach uses features generated by a multi-channel coherence analysis (MCA), which is an extension of CCA utilizing multiple sonar pings. The MCA features are then applied to a simple classifier. Results are presented in terms of correct classification rate and general detection and classification performance of each system in relation to the various operating and environmental conditions.

  13. Salt Plug Formation Caused by Decreased River Discharge in a Multi-channel Estuary

    NASA Astrophysics Data System (ADS)

    Shaha, Dinesh Chandra; Cho, Yang-Ki

    2016-06-01

    Freshwater input to estuaries may be greatly altered by the river barrages required to meet human needs for drinking water and irrigation and prevent salt water intrusion. Prior studies have examined the salt plugs associated with evaporation and salt outwelling from tidal salt flats in single-channel estuaries. In this work, we discovered a new type of salt plug formation in the multi-channel Pasur River Estuary (PRE) caused by decreasing river discharges resulting from an upstream barrage. The formation of a salt plug in response to changes in river discharge was investigated using a conductivity-temperature-depth (CTD) recorder during spring and neap tides in the dry and wet seasons in 2014. An exportation of saline water from the Shibsa River Estuary (SRE) to the PRE through the Chunkhuri Channel occurred during the dry season, and a salt plug was created and persisted from December to June near Chalna in the PRE. A discharge-induced, relatively high water level in the PRE during the wet season exerted hydrostatic pressure towards the SRE from the PRE and thereby prevented the intrusion of salt water from the SRE to the PRE.

  14. Multi-channel and multi-scale mid-level image representation for scene classification

    NASA Astrophysics Data System (ADS)

    Yang, Jinfu; Yang, Fei; Wang, Guanghui; Li, Mingai

    2017-03-01

    Convolutional neural network (CNN)-based approaches have received state-of-the-art results in scene classification. Features from the output of fully connected (FC) layers express one-dimensional semantic information but lose the detailed information of objects and the spatial information of scene categories. On the contrary, deep convolutional features have been proved to be more suitable for describing an object itself and the spatial relations among objects in an image. In addition, the feature map from each layer is max-pooled within local neighborhoods, which weakens the invariance of global consistency and is unfavorable to scenes with highly complicated variation. To cope with the above issues, an orderless multi-channel mid-level image representation on pre-trained CNN features is proposed to improve the classification performance. The mid-level image representation of two channels from the FC layer and the deep convolutional layer are integrated at multi-scale levels. A sum pooling approach is also employed to aggregate multi-scale mid-level image representation to highlight the importance of the descriptors beneficial for scene classification. Extensive experiments on SUN397 and MIT 67 indoor datasets demonstrate that the proposed method achieves promising classification performance.

  15. Dimensionality Reduction on Multi-Dimensional Transfer Functions for Multi-Channel Volume Data Sets

    PubMed Central

    Kim, Han Suk; Schulze, Jürgen P.; Cone, Angela C.; Sosinsky, Gina E.; Martone, Maryann E.

    2011-01-01

    The design of transfer functions for volume rendering is a non-trivial task. This is particularly true for multi-channel data sets, where multiple data values exist for each voxel, which requires multi-dimensional transfer functions. In this paper, we propose a new method for multi-dimensional transfer function design. Our new method provides a framework to combine multiple computational approaches and pushes the boundary of gradient-based multi-dimensional transfer functions to multiple channels, while keeping the dimensionality of transfer functions at a manageable level, i.e., a maximum of three dimensions, which can be displayed visually in a straightforward way. Our approach utilizes channel intensity, gradient, curvature and texture properties of each voxel. Applying recently developed nonlinear dimensionality reduction algorithms reduces the high-dimensional data of the domain. In this paper, we use Isomap and Locally Linear Embedding as well as a traditional algorithm, Principle Component Analysis. Our results show that these dimensionality reduction algorithms significantly improve the transfer function design process without compromising visualization accuracy. We demonstrate the effectiveness of our new dimensionality reduction algorithms with two volumetric confocal microscopy data sets. PMID:21841914

  16. Dimensionality Reduction on Multi-Dimensional Transfer Functions for Multi-Channel Volume Data Sets.

    PubMed

    Kim, Han Suk; Schulze, Jürgen P; Cone, Angela C; Sosinsky, Gina E; Martone, Maryann E

    2010-09-21

    The design of transfer functions for volume rendering is a non-trivial task. This is particularly true for multi-channel data sets, where multiple data values exist for each voxel, which requires multi-dimensional transfer functions. In this paper, we propose a new method for multi-dimensional transfer function design. Our new method provides a framework to combine multiple computational approaches and pushes the boundary of gradient-based multi-dimensional transfer functions to multiple channels, while keeping the dimensionality of transfer functions at a manageable level, i.e., a maximum of three dimensions, which can be displayed visually in a straightforward way. Our approach utilizes channel intensity, gradient, curvature and texture properties of each voxel. Applying recently developed nonlinear dimensionality reduction algorithms reduces the high-dimensional data of the domain. In this paper, we use Isomap and Locally Linear Embedding as well as a traditional algorithm, Principle Component Analysis. Our results show that these dimensionality reduction algorithms significantly improve the transfer function design process without compromising visualization accuracy. We demonstrate the effectiveness of our new dimensionality reduction algorithms with two volumetric confocal microscopy data sets.

  17. Monitoring of ion implantation in microelectronics production environment using multi-channel reflectometry

    NASA Astrophysics Data System (ADS)

    Ebersbach, Peter; Urbanowicz, Adam M.; Likhachev, Dmitry; Hartig, Carsten

    2016-03-01

    Optical metrology techniques such as ellipsometry and reflectometry are very powerful for routine process monitoring and control in the modern semiconductor manufacturing industry. However, both methods rely on optical modeling therefore, the optical properties of all materials in the stack need to be characterized a priori or determined during characterization. Some processes such as ion implantation and subsequent annealing produce slight variations in material properties within wafer, wafer-to-wafer, and lot-to-lot; such variation can degrade the dimensional measurement accuracy for both unpatterned optical measurements as well as patterned (2D and 3D) scatterometry measurements. These variations can be accounted for if the optical model of the structure under investigation allows one to extract not just dimensional but also material information already residing within the optical spectra. This paper focuses on modeling of ion implanted and annealed poly Si stacks typically used in high-k technology. Monitoring of ion implantation is often a blind spot in mass production due to capability issues and other limitations of common methods. Typically, the ion implantation dose can be controlled by research-grade ellipsometers with extended infrared range. We demonstrate that multi-channel spectroscopic reflectometry can also be used for ion implant monitoring in the mass-production environment. Our findings are applicable across all technology nodes.

  18. Proximal ADMM for multi-channel image reconstruction in spectral X-ray CT.

    PubMed

    Sawatzky, Alex; Xu, Qiaofeng; Schirra, Carsten O; Anastasio, Mark A

    2014-08-01

    The development of spectral X-ray computed tomography (CT) using binned photon-counting detectors has received great attention in recent years and has enabled selective imaging of contrast agents loaded with K-edge materials. A practical issue in implementing this technique is the mitigation of the high-noise levels often present in material-decomposed sinogram data. In this work, the spectral X-ray CT reconstruction problem is formulated within a multi-channel (MC) framework in which statistical correlations between the decomposed material sinograms can be exploited to improve image quality. Specifically, a MC penalized weighted least squares (PWLS) estimator is formulated in which the data fidelity term is weighted by the MC covariance matrix and sparsity-promoting penalties are employed. This allows the use of any number of basis materials and is therefore applicable to photon-counting systems and K-edge imaging. To overcome numerical challenges associated with use of the full covariance matrix as a data fidelity weight, a proximal variant of the alternating direction method of multipliers is employed to minimize the MC PWLS objective function. Computer-simulation and experimental phantom studies are conducted to quantitatively evaluate the proposed reconstruction method.

  19. Development of multi-channel gated integrator and PXI-DAQ system for nuclear detector arrays

    NASA Astrophysics Data System (ADS)

    Kong, Jie; Su, Hong; Chen, Zhi-Qiang; Dong, Cheng-Fu; Qian, Yi; Gao, Shan-Shan; Zhou, Chao-Yang; Lu, Wan; Ye, Rui-Ping; Ma, Jun-Bing

    2010-10-01

    A multi-channel gated integrator and PXI based data acquisition system have been developed for nuclear detector arrays with hundreds of detector units. The multi-channel gated integrator can be controlled by a programmable GI controller. The PXI-DAQ system consists of NI PXI-1033 chassis with several PXI-DAQ cards. The system software has a user-friendly GUI which is written in C language using LabWindows/CVI under Windows XP operating system. The performance of the PXI-DAQ system is very reliable and capable of handling event rate up to 40 kHz.

  20. Study on the separation performance of the multi-channel reduced graphene oxide membranes

    NASA Astrophysics Data System (ADS)

    Zhao, Yongjiao; Li, Chun; Fan, Xiaoyan; Wang, Jiesheng; Yuan, Guang; Song, Xinxiang; Chen, Jing; Li, Zhangde

    2016-10-01

    The multi-channel reduced graphene oxide membranes with separation function have been synthesized by a simple hydrothermal reduction method and vacuum filtration. In the as-synthesized membranes, the size, number, and type of the nanochannels can be controlled by the reduced temperature. The flux and retention rate of solution are investigated by filtering different size dye molecules. The interception and adsorption effect in the separation process are discussed. Furthermore, the sizes of the nanochannels in the membranes prepared by the different reduced temperatures are estimated. The results indicate that the multi-channel reduced graphene oxide membranes have potential application in water purification area.

  1. The Use of Continuous Wavelet Transform Based on the Fast Fourier Transform in the Analysis of Multi-channel Electrogastrography Recordings.

    PubMed

    Komorowski, Dariusz; Pietraszek, Stanislaw

    2016-01-01

    This paper presents the analysis of multi-channel electrogastrographic (EGG) signals using the continuous wavelet transform based on the fast Fourier transform (CWTFT). The EGG analysis was based on the determination of the several signal parameters such as dominant frequency (DF), dominant power (DP) and index of normogastria (NI). The use of continuous wavelet transform (CWT) allows for better visible localization of the frequency components in the analyzed signals, than commonly used short-time Fourier transform (STFT). Such an analysis is possible by means of a variable width window, which corresponds to the scale time of observation (analysis). Wavelet analysis allows using long time windows when we need more precise low-frequency information, and shorter when we need high frequency information. Since the classic CWT transform requires considerable computing power and time, especially while applying it to the analysis of long signals, the authors used the CWT analysis based on the fast Fourier transform (FFT). The CWT was obtained using properties of the circular convolution to improve the speed of calculation. This method allows to obtain results for relatively long records of EGG in a fairly short time, much faster than using the classical methods based on running spectrum analysis (RSA). In this study authors indicate the possibility of a parametric analysis of EGG signals using continuous wavelet transform which is the completely new solution. The results obtained with the described method are shown in the example of an analysis of four-channel EGG recordings, performed for a non-caloric meal.

  2. Developing imaging capabilities of multi-channel detectors comparable to traditional x-ray detector technology for industrial and security applications

    NASA Astrophysics Data System (ADS)

    Jimenez, Edward S.; Collins, Noelle M.; Holswade, Erica A.; Devonshire, Madison L.; Thompson, Kyle R.

    2016-10-01

    This work will investigate the imaging capabilities of the Multix multi-channel linear array detector and its potential suitability for big-data industrial and security applications versus that which is currently deployed. Multi-channel imaging data holds huge promise in not only finer resolution in materials classification, but also in materials identification and elevated data quality for various radiography and computed tomography applications. The potential pitfall is the signal quality contained within individual channels as well as the required exposure and acquisition time necessary to obtain images comparable to those of traditional configurations. This work will present results of these detector technologies as they pertain to a subset of materials of interest to the industrial and security communities; namely, water, copper, lead, polyethylene, and tin.

  3. Preliminary Interpretations of Multi-Channel Seismic Reflection and Magnetic Data on North Anatolian Fault (NAF) in the Eastern Marmara Region, Turkey

    NASA Astrophysics Data System (ADS)

    Gözde Okut Toksoy, Nigar; Kurt, Hülya; İşseven, Turgay

    2017-04-01

    The North Anatolian Fault (NAF) is 1600 km long, right lateral strike-slip fault nearly E-W elongated between Karlıova in the east and Saros Gulf in the west. NAF splays into two major strands near the west of Bolu city as Northern and Southern strands. Northern strand passes Sapanca Lake and extends towards west and reaches Marmara Sea through the Gulf of Izmit. The area has high seismicity; 1999 Kocaeli (Mw=7.4) and 1999 Düzce (Mw=7.2) earthquakes caused approximately 150 km long surface rupture between the Gulf of Izmit and Bolu. The rupture has four distinct fault segments as Gölcük, Sapanca, Sakarya, and Karadere from west to east. In this study multi-channel seismic and magnetic data are collected for the first time on the Sapanca Segment to investigate the surficial and deeper geometry of the NAF. Previously, the NAF in the eastern Marmara region is investigated using by paleo-seismological data from trenches on the surface rupture of fault or the geomorphological data (Lettis et al., 2000; Dikbaş and Akyüz, 2010) which have shallower depth targets. Crustal structure and seismic velocities for Central Anatolia and eastern Marmara regions are obtained from deeper targeted refraction data (Gürbüz et al., 1992). However, their velocity models do not have the spatial resolution to determine details of the fault zone structure. Multi-channel seismic and magnetic data in this study were acquired on two N-S directed profiles crossing NAF perpendicularly near Kartepe on the western part of the Sapanca Lake in October 2016. The receiver interval is 5 m, shot interval is 5-10 m, and the total length of the profiles are approximately 1400 m. Buffalo Gun is used as a seismic source for deeper penetration. Conventional seismic reflection processing steps are applied to the data. These are geometry definition, editing, filtering, static correction, velocity analysis and deconvolution, stacking and migration. Echos seismic software package in Geophysical Department

  4. Using image synthesis for multi-channel registration of different image modalities

    PubMed Central

    Chen, Min; Jog, Amod; Carass, Aaron; Prince, Jerry L.

    2015-01-01

    This paper presents a multi-channel approach for performing registration between magnetic resonance (MR) images with different modalities. In general, a multi-channel registration cannot be used when the moving and target images do not have analogous modalities. In this work, we address this limitation by using a random forest regression technique to synthesize the missing modalities from the available ones. This allows a single channel registration between two different modalities to be converted into a multi-channel registration with two mono-modal channels. To validate our approach, two openly available registration algorithms and five cost functions were used to compare the label transfer accuracy of the registration with (and without) our multi-channel synthesis approach. Our results show that the proposed method produced statistically significant improvements in registration accuracy (at an α level of 0.001) for both algorithms and all cost functions when compared to a standard multi-modal registration using the same algorithms with mutual information. PMID:26246653

  5. Raman Spectroscopy of Bacillus megaterium Using an Optical Multi-channel Analyzer

    NASA Astrophysics Data System (ADS)

    Layne, Scott P.; Bigio, Irving J.

    1986-01-01

    Using a spectrometer equipped with an optical multi-channel analyzer as the detector, we have observed the Stokes laser-Raman spectra of metabolically active B. megaterium from 930-1720 cm-1. No Raman lines attributable to the metabolic process nor the cells themselves were found. This result is consistent with our previous laser-Raman measurements of synchronous E. coli cultures.

  6. Using image synthesis for multi-channel registration of different image modalities.

    PubMed

    Chen, Min; Jog, Amod; Carass, Aaron; Prince, Jerry L

    2015-02-21

    This paper presents a multi-channel approach for performing registration between magnetic resonance (MR) images with different modalities. In general, a multi-channel registration cannot be used when the moving and target images do not have analogous modalities. In this work, we address this limitation by using a random forest regression technique to synthesize the missing modalities from the available ones. This allows a single channel registration between two different modalities to be converted into a multi-channel registration with two mono-modal channels. To validate our approach, two openly available registration algorithms and five cost functions were used to compare the label transfer accuracy of the registration with (and without) our multi-channel synthesis approach. Our results show that the proposed method produced statistically significant improvements in registration accuracy (at an α level of 0.001) for both algorithms and all cost functions when compared to a standard multi-modal registration using the same algorithms with mutual information.

  7. Flood tolerance evaluation of bottomland oaks in a multi-channel field laboratory

    Treesearch

    Mark V. Coggeshall; J. W. Van Sambeek; Scott E. Schlarbaum

    2005-01-01

    A multi-channel field laboratory was designed and constructed by the University of Missouri Center for Agroforestry at the Horticulture and Agroforestry Research Center to assess the flood tolerance of forages and hardwood seedlings. This facility located in the Missouri River floodplain consists of twelve 6-m wide x 180-m long channels that had minimal disturbance to...

  8. A Multi-Channel Approach for Collaborative Web-Based Learning

    ERIC Educational Resources Information Center

    Azeta, A. A.

    2008-01-01

    This paper describes an architectural framework and a prototype implementation of a web-based multi-channel e-Learning application that allows students, lecturers and the research communities to collaborate irrespective of the communication device a user is carrying. The application was developed based on the concept of "right once run on any…

  9. A multi-channel, optically coupled spark gap monitor system

    SciTech Connect

    Gribble, R.; Barnes, G.A.

    1987-10-01

    A spark gap monitor system has been installed on FRX-C Large Source Modification, a theta pinch experiment which forms field-reversed configuration (FRC) compact toroids. The field reversing theta pinch produces a vacuum magnetic field of 10kG inside the single turn, 2-m-long straight 0.7-id coil by discharging in series two 50kV, 200..mu..F capacitor banks with a total of 140 2.8..mu..F capacitors each with a start spark-gap switch and a ''piggy-back'' crowbar spark-gap switch. Efficient operation of the bank requires information on the timing and function of each capacitor-spark gap unit. Diagnosing the capacitor-spark-gap unit load cable current (approximately 3kA per cable) is complicated by the fact that the ground return for the capacitor is of a relatively high impedance. Units that are allowed to prefire or postfire not only degrade the performance of the bank but will self destruct or destroy their neighbors. To provide this information without introducing high voltage transients into the data acquisition and control system as optically coupled, 140 channel gap monitor system has been installed. Simplicity and reliability were key requirements in the design of the system. A resistor made of thin wall stainless steel tubing replaces a short section of the braid on one load cable on each capacitor. The voltage developed across the resistor provides the current source to drive an LED. The relatively linear output from the LED is transmitted through approximately 30m of fiber optic cable to the FRX-C control room. The signal is received by a photo diode and simple amplifier circuit that feeds the signal into a 12 channel charge integrating ADC CAMAC module for processing by the computer. The information provided by this system informs the operator as to when and how each gap fired. 2 refs., 8 figs.

  10. TUKAN—An 8K Pulse Height Analyzer and Multi-Channel Scaler With a PCI or a USB Interface

    NASA Astrophysics Data System (ADS)

    Guzik, Z.; Borsuk, S.; Traczyk, K.; Plominski, M.

    2006-02-01

    In this paper we present two types of 8K-channel analyzers designed for spectroscopy and intensity versus time measurements. The first type (Tukan-8K-PCI) incorporates a PCI interface and is designed to be plugged into a PCI slot of a normal PC. The second type (Tukan-8K-USB) incorporates a USB interface. It is mounted in a separate screened box and can be powered either directly from the USB port or from an external dc source (wall adapter or battery). Each type of device may operate in either of two independent operational modes: Multi Channel Analysis (MCA) and Multi-Channel Scaling (MCS). The most crucial component for the MCA mode-the Peak Detect and Hold circuit-is featuring a novel architecture based on a diamond transistor. Its analog stage can accept analog pulses with rise times as short as 100 ns and has a differential linearity below 1% with sliding scale averaging over the full scale. The functionality includes automatic stop on a programmable count in the Region-Of-Interest (ROI) and on preset live- or real time. The MCS mode works at medium counting rates of up to 8 MHz. The dwell time, the number of channels and single or multi-sweep mode may be preset. Each of these parameters can also be controlled externally via four user configurable logical I/O lines. A single Altera FLEX 10KE30 FPGA provides all control functions and incorporates PCI interface. The USB interface is based on FTDI FIFO controller. Advanced and user-friendly software has been developed for the analyzer

  11. Retrievals on Tropical small scale humidity variability from multi-channel microwave radiometer

    NASA Astrophysics Data System (ADS)

    Zhang, Jianhao; Zuidema, Paquita; Turner, David

    2016-04-01

    Small-scale atmospheric humidity structure is important to many atmospheric process studies. In the Tropics especially, convection is sensitive to small variations in humidity. High temporal-resolution humidity profiles and spatially-resolved humidity fields are valuable for understanding the relationship of convection to tropical humidity, such as at convectively-induced cold pools and as part of the shallow-to-deep cloud transition. Radiosondes can provide high resolution vertical profiles of temperature and humidity, but are relatively infrequent. Microwave radiometers (MWR) are able to profile and scan autonomously and output measurements frequently (~1 Hz). To date, few assessments of microwave humidity profiling in the Tropics have been undertaken. Löhnert et al. (2009) provide one evaluation for Darwin, Australia. We build on this using four months of data from the equatorial Indian Ocean, at Gan Island, collected from University of Miami's (UM) multi-channel radiometer during the Dynamics of Madden-Julian Oscillation (DYNAMO) field campaign. Liquid Water Path (LWP) and Water Vapor Path (WVP) are physically retrieved using the MWR RETrieval (MWRRET) algorithm (Turner et al., 2007b), and humidity profiles in the tropics are retrieved using the Integrated Profiling Technique (Löhnert et al., 2004). Tropical temperature variability is weak and a climatological temperature profile is assumed, with humidity information drawn from five channels between 22 to 30 GHz. Scanning measurements were coordinated with the scanning pattern of NCAR's S-Pol-Ka radar. An analysis of the humidity information content gathered from both the profiling and scanning measurements will be presented.

  12. Anisoplanatic studies and Fried parameter estimation via multi-channel laser communication system

    NASA Astrophysics Data System (ADS)

    Sergeyev, A.; Roggemann, M.

    The knowledge of the turbulence conditions and the ability to describe its properties are the key aspects to improve performance and extend the range of optical communication systems. The developed multi-channel, outdoor 3.2 km, partially over water, turbulence measurement and monitoring communication platform is directed to collect significant amount of the experimental data with the goal of statistically describe atmospheric turbulence. The communication system described in this paper has two transmitters and two receivers. The transmitter side is equipped with the laser and the bank of 14 horizontally, in-line mounted LEDs. The receiver side consists of two channels for wave front sensor (WFS) and point spread function (PSF) measurements. Data collected via both channels is further used for Fried parameter estimation and anisoplanatic studies. In this article authors provide comprehensive analysis of the turbulence statistics extracted from the experimental data. Statistics of Freid parameter r0 is derived from 6 Tb of data collected through 40 days time interval, and under various day and night atmospheric conditions. These data collected from WFS and PSF channels are digitally post processed and results obtained from PSF measurements are compared with the ones derived from the WFS data. Consistent results obtained via both channels allows authors to conclude that the entire system performs reliably and generates trustworthy results. Results extracted from the data collected via both channels show significant fluctuations of r0 with the values ranging from 2mm and up to 20 cm. The data collected from the PSF channel is also used for measurements of anisoplanetic effects. Theoretically, the severe anisoplanatic conditions found in horizontally imaging scenarios can be approximated by a finite number of phase screens placed along the imaging path. However, comparison of adjacent PSFs generated in this manner reveals significant correlation a- angles much larger

  13. Measurement of mode coupling distribution along a few-mode fiber using a synchronous multi-channel OTDR.

    PubMed

    Nakazawa, Masataka; Yoshida, Masato; Hirooka, Toshihiko

    2014-12-15

    We describe the nondestructive measurement of mode coupling along a few-mode fiber using a synchronous multi-channel optical time-domain reflectometer (OTDR). By installing a few-mode fiber (FMF) coupler made with a phase mask method, we excite the LP01 mode in an FMF under the test as an input mode, and then we detect backward Rayleigh scattered LP11a or LP11b modes, which were generated as a result of the mode coupling through the coupler. The mode coupling distribution between the LP01 and LP11a,b modes along the test FMF was successfully measured with a 10-m spatial resolution by obtaining the ratio between the backscattered LP01 mode and LP11a or LP11b. The value of the mode coupling obtained with the present method agreed well with that obtained with the conventional transmission method.

  14. Materials characterization for process integration of multi-channel gate all around (GAA) devices

    NASA Astrophysics Data System (ADS)

    Muthinti, Gangadhara Raja; Loubet, Nicolas; Chao, Robin; de la Peña, Abraham A.; Li, Juntao; Guillorn, Michael A.; Yamashita, Tenko; Kanakasabapathy, Sivananda; Gaudiello, John; Cepler, Aron J.; Sendelbach, Matthew; Emans, Susan; Wolfling, Shay; Ger, Avron; Kandel, Daniel; Koret, Roy; Lee, Wei Ti; Gin, Peter; Matney, Kevin; Wormington, Matthew

    2017-03-01

    Multi-channel gate all around (GAA) semiconductor devices march closer to becoming a reality in production as their maturity in development continues. From this development, an understanding of what physical parameters affecting the device has emerged. The importance of material property characterization relative to that of other physical parameters has continued to increase for GAA architecture when compared to its relative importance in earlier architectures. Among these materials properties are the concentration of Ge in SiGe channels and the strain in these channels and related films. But because these properties can be altered by many different process steps, each one adding its own variation to these parameters, their characterization and control at multiple steps in the process flow is crucial. This paper investigates the characterization of strain and Ge concentration, and the relationships between these properties, in the PFET SiGe channel material at the earliest stages of processing for GAA devices. Grown on a bulk Si substrate, multiple pairs of thin SiGe/Si layers that eventually form the basis of the PFET channel are measured and characterized in this study. Multiple measurement techniques are used to measure the material properties. In-line X-Ray Photoelectron Spectroscopy (XPS) and Low Energy X-Ray Fluorescence (LE-XRF) are used to characterize Ge content, while in-line High Resolution X-Ray Diffraction (HRXRD) is used to characterize strain. Because both patterned and un-patterned structures were investigated, scatterometry (also called optical critical dimension, or OCD) is used to provide valuable geometrical metrology.

  15. Multi-Channel Seismic Images of the Mariana Forearc: EW0202 Initial Results

    NASA Astrophysics Data System (ADS)

    Oakley, A. J.; Goodliffe, A. M.; Taylor, B.; Moore, G. F.; Fryer, P.

    2002-12-01

    During the Spring of 2002, the Mariana Subduction Factory was surveyed using multi-channel seismics (MCS) as the first major phase of a US-Japanese collaborative NSF-MARGINS funded project. The resulting geophysical transects extend from the Pacific Plate to the West Mariana remnant arc. For details of this survey, including the results from the back-arc, refer to Taylor et al. (this session). The incoming Pacific Plate and its accompanying seamounts are deformed by plate flexure, resulting in extension of the upper crust as it enters the subduction zone. The resultant trench parallel faults dominate the bathymetry and MCS data. Beneath the forearc, in the southern transects near Saipan, the subducting slab is imaged to a distance of 50-60 km arcward. In addition to ubiquitous trench parallel normal faulting, a N-S transect of the forearc clearly shows normal faults perpendicular to the trench resulting from N-S extension. On the east side of the Mariana Ridge, thick sediment packages extend into the forearc. Directly east of Saipan and Tinian, a large, deeply scouring slide mass is imaged. Several serpentine mud volcanoes (Big Blue, Turquoise and Celestial) were imaged on the Mariana Forearc. Deep horizontal reflectors (likely original forearc crust) are imaged under the flanks of some of these seamounts. A possible "throat" reflector is resolved on multiple profiles at the summit of Big Blue, the northern-most seamount in the study area. The flanks of Turquoise seamount terminate in toe thrusts that represent uplift and rotation of surrounding sediments as the volcano grows outward. These thrusts form a basal ridge around the seamount similar to that previously noted encircling Conical Seamount. Furthermore, MCS data has revealed that some forearc highs previously thought to be fault blocks are in actuality mud volcanoes.

  16. Smart multi-channel two-dimensional micro-gas chromatography for rapid workplace hazardous volatile organic compounds measurement.

    PubMed

    Liu, Jing; Seo, Jung Hwan; Li, Yubo; Chen, Di; Kurabayashi, Katsuo; Fan, Xudong

    2013-03-07

    We developed a novel smart multi-channel two-dimensional (2-D) micro-gas chromatography (μGC) architecture that shows promise to significantly improve 2-D μGC performance. In the smart μGC design, a non-destructive on-column gas detector and a flow routing system are installed between the first dimensional separation column and multiple second dimensional separation columns. The effluent from the first dimensional column is monitored in real-time and decision is then made to route the effluent to one of the second dimensional columns for further separation. As compared to the conventional 2-D μGC, the greatest benefit of the smart multi-channel 2-D μGC architecture is the enhanced separation capability of the second dimensional column and hence the overall 2-D GC performance. All the second dimensional columns are independent of each other, and their coating, length, flow rate and temperature can be customized for best separation results. In particular, there is no more constraint on the upper limit of the second dimensional column length and separation time in our architecture. Such flexibility is critical when long second dimensional separation is needed for optimal gas analysis. In addition, the smart μGC is advantageous in terms of elimination of the power intensive thermal modulator, higher peak amplitude enhancement, simplified 2-D chromatogram re-construction and potential scalability to higher dimensional separation. In this paper, we first constructed a complete smart 1 × 2 channel 2-D μGC system, along with an algorithm for automated control/operation of the system. We then characterized and optimized this μGC system, and finally employed it in two important applications that highlight its uniqueness and advantages, i.e., analysis of 31 workplace hazardous volatile organic compounds, and rapid detection and identification of target gas analytes from interference background.

  17. Development and Experimental Validation of a Dry Non-Invasive Multi-Channel Mouse Scalp EEG Sensor through Visual Evoked Potential Recordings

    PubMed Central

    Kim, Donghyeon; Yeon, Chanmi; Kim, Kiseon

    2017-01-01

    In this paper, we introduce a dry non-invasive multi-channel sensor for measuring brainwaves on the scalps of mice. The research on laboratory animals provide insights to various practical applications involving human beings and other animals such as working animals, pets, and livestock. An experimental framework targeting the laboratory animals has the potential to lead to successful translational research when it closely resembles the environment of real applications. To serve scalp electroencephalography (EEG) research environments for the laboratory mice, the dry non-invasive scalp EEG sensor with sixteen electrodes is proposed to measure brainwaves over the entire brain area without any surgical procedures. We validated the proposed sensor system with visual evoked potential (VEP) experiments elicited by flash stimulations. The VEP responses obtained from experiments are compared with the existing literature, and analyzed in temporal and spatial perspectives. We further interpret the experimental results using time-frequency distribution (TFD) and distance measurements. The developed sensor guarantees stable operations for in vivo experiments in a non-invasive manner without surgical procedures, therefore exhibiting a high potential to strengthen longitudinal experimental studies and reliable translational research exploiting non-invasive paradigms. PMID:28208777

  18. Observation of three-dimensional structures of quasi-periodic echoes associated with mid-latitude sporadic-E layers by MU radar ultra-multi-channel system

    NASA Astrophysics Data System (ADS)

    Saito, S.; Yamamoto, M.; Hashiguchi, H.; Maegawa, A.

    2006-07-01

    Quasi-periodic (QP) backscatter observed by VHF radars associated with the mid-latitude Sporadic-E (Es) layers is characterized by distinct striations on range-time-intensity (RTI) plots. Two competing models claim to explain the structure of unstable regions that scatter the radar waves: horizontally drifting patches at an almost constant altitude and unstable regions elongated in altitude along the geomagnetic field line. We have conducted interferometric imaging observations of QP radar echoes to investigate spatial structures of QP echoes, precisely. Kyoto University's newly developed ultra-multi-channel receiving system of middle and upper atmosphere (MU) radar was used. We used 19 independent channels for the radar imaging, and determined the three-dimensional structure and the motion of the QP echoes. During the observation from 30 May to 02 June 2005, well-defined QP echoes were observed on the nights of 31 May, 01 June, and 02 June 2005. Some of QP echoes were found at altitudes higher than 120 km and appeared to descend in altitude as they approached the radar. This result suggests that backscatter regions are developed along the geomagnetic field line from Es layer altitudes to as high as 130 km and that the fluctuations in plasma density and electric field observed by Pfaff et al. (2005) using in-situ measurements form a part of QP echoes.

  19. Nonlinear Dynamics of Multi-Channel Binocular Vision.

    DTIC Science & Technology

    1985-12-13

    behavioral organization, have translated these principles into real-time adaptive neural networks, have used these models to unify the explanation of...the funding cycle. In addition to our modelling work. several articles reporting experimental results on surface perception (shape-from-shading) have...1985 Books +1. Grossberg. S.. Neural Models in Psychology: The Grossberg Lectures. P. Killeen and D. Hestenes (Eds.). Hillsdale. NJ: Erlbaum. 1985

  20. Nonlinear Dynamics of Multi-Channel Binocular Vision.

    DTIC Science & Technology

    1984-03-07

    terprets and generalizes Land’s retinex theory of color vision, and unifies the explanation of monocular and binocular brightness data. The simulated...induction, and filling-in of discounted illuminants 3nd scotomas. The theory also physically interprets and generalizes Land’s retinex theory. These...cortex. B. SENSORY-MOTOR CONTROL Visual representations influence and are influenced by processes of motor control. A real-time theory has been

  1. Multi-Channel Parametric Estimator Fast Block Matrix Inverses

    DTIC Science & Technology

    2007-04-01

    updates for cp, dp, e c p[n], and edp[n] are a part of the fast MC algorithm, but not shown here. The inverse matrix ( XpX H p )−1 can be explicitly...Rangaswamy, M. C. Wicks, R. Adve, and T. B. Hale, “Space-time adaptive procesing : a knowledge-based perspective for airborne radar,” IEEE Signal Processing

  2. Multi-channel amplifier system for computerized topographic EEG analysis.

    PubMed

    Coppola, R; Morgan, N T

    1987-08-01

    Topographic analysis of EEG and evoked potentials requires the computer processing of data from multi-lead recording. The use of 20 or more channels is now quite common, straining the resources of the usual EEG machine. We present a design for a high gain, low noise, 32-channel amplifier matched to computer data acquisition requirements. Low cost and small size are additional benefits to the design.

  3. Multi-Channel Integrated Circuits For Use In Research With Radioactive Ion Beams

    NASA Astrophysics Data System (ADS)

    Engel, G. L.; Vangapally, V.; Duggireddi, N.; Sobotka, L. G.; Elson, J. M.; Charity, R. J.

    2011-06-01

    The Integrated Circuits Design Research Laboratory at Southern Illinois University Edwardsville (SIUE) has been collaborating over the past several years with the Nuclear Reactions Group at Washington University (WU) on the development of a family of custom, multi-channel Integrated Circuits (ICs). To date, the collaboration has successfully produced two micro-chips. The first was an analog shaped and peak sensing chip known as HINP16C (Heavy Ion Nuclear Physics—16 Channel). The second chip, christened PSD8C (Pulse Shape Discrimination—8 Channel), was designed to logically complement (in terms of detector types) the HINP16C chip. The HINP16C chip, for use with solid-state detectors, produces sparsified analog pulse trains for both linear (pulse height) and timing (relative to an external reference) signals. A shaper and peak detector are implemented in the linear branch, and a pseudo Constant-Fraction Discriminator (CFD) and Time-to-Voltage Converter (TVC) are implemented in the logic/timing branch. The internal and external gain options make the chip suitable for use in a wide variety of applications. PSD8C greatly simplifies the pulse-processing electronics needed for large arrays of scintillation detectors. As the PSD8C employs user-controlled, multi-region charge integration, particle identification is inherent in the design. Each of the three pulse-height sub-channels consists of a gated integrator with eight programmable charging rates and an externally programmable gate generator that defines the start (with 4 time ranges) and the width (with 4 time ranges) of the gate, relative to an external discriminator signal. Moreover, each channel on the chip also contains a TVC. This paper describes the design, capabilities, and features of the HINP16C and PSD8C ICs along with a description of how the chips are being used. It also discusses modifications and enhancements which have been made to both chips and their associated prototypical systems in order to

  4. Multi-channel Scaler Cards Improve Data Collection

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Scientists interested in exploring the intricacies and dynamics of Earth's climate and ecosystems continually need smaller, lighter instrumentation that can be placed onboard various sensing platforms, such as Unmanned Aerial Vehicles (UAVs). Responding to a need for improved data collection for remote atmospheric measurement systems, ASRC Aerospace Corporation, of Greenbelt, Maryland, developed a series of low-power, highly integrated, multichannel scaler (MCS) cards. The cards were designed to meet the needs of NASA's ground-based and airborne Light Detection and Ranging (LIDAR) photoncounting programs. They can rapidly collect thousands of data points during a continuous scan of the atmosphere.

  5. Multi-Channel Electronically Scanned Cryogenic Pressure Sensor And Method For Making Same

    NASA Technical Reports Server (NTRS)

    Chapman, John J. (Inventor); Hopson, Purnell, Jr. (Inventor); Holloway, Nancy M. (Inventor)

    2001-01-01

    A miniature, multi-channel, electronically scanned pressure measuring device uses electrostatically bonded silicon dies in a multi-element array. These dies are bonded at specific sites on a glass, pre-patterned substrate. Thermal data is multiplexed and recorded on each individual pressure measuring diaphragm. The device functions in a cryogenic environment without the need of heaters to keep the sensor at constant temperatures.

  6. Avian embryo monitoring during incubation using multi-channel diffuse speckle contrast analysis

    PubMed Central

    Yeo, Chaebeom; Park, Hyun-cheol; Lee, Kijoon; Song, Cheol

    2015-01-01

    Determining the survival rate of avian embryos during incubation is essential for cost-saving in the poultry industry. A multi-channel diffuse speckle contrast analysis (DSCA) system, comprising four optical fiber channels, is proposed to achieve noninvasive in vivo measurements of deep tissue flow. The system was able to monitor chick embryo vital signs over the entire incubation period. Moreover, it proved useful in distinguishing between chick embryos in healthy and weakened conditions. PMID:26819820

  7. Multi-channel orbital angular momentum detection with metahologram.

    PubMed

    Rui, Guanghao; Ma, Yanbao; Gu, Bing; Zhan, Qiwen; Cui, Yiping

    2016-09-15

    Orbital angular momentum (OAM) is an intrinsic property of light that has attracted increasing attention recently. In a wide range of applications that involve OAM, it is often crucial to discern the OAM states with high fidelity. In this Letter, we propose a novel method to extend the detectable range of the OAM states by adopting a multi-sector metahologram. The incident light carrying OAM would be focused by the metahologram into surface plasmon waves with separated propagation directions that are spatially sampled by multiple subwavelength detectors. Through quantizing and mapping the detector signals into a lookup table, a wide range of OAM states could be distinguished. The principle reported in this Letter may find important applications in optical communications and information processing with the OAM states.

  8. Method of multi-channel data readout and acquisition

    DOEpatents

    Degtiarenko, Pavel V.; Popov, Vladimir E.

    2010-06-15

    A method for dealing with the problem of simultaneous continuous readout of large number of data channels from the set of multiple sensors in instances where the use of multiple amplitude-to-digital converters is not practical or causes undesirable extra noise and distortion in the data. The new method uses sensor front-end s and subsequent electronics to transform the analog input signals and encode them into a series of short pulses that can be transmitted to a long distance via a high frequency transmission line without information loss. Upon arrival at a destination data decoder and analyzer device, the series of short pulses can be decoded and transformed back, to obtain, store, and utilize the sensor information with the required accuracy.

  9. A robotic multi-channel platform for interstitial photodynamic therapy

    PubMed Central

    Sharikova, Anna V.; Finlay, Jarod C.; Dimofte, Andreea; Zhu, Timothy C.

    2015-01-01

    A custom-made robotic multichannel platform for interstitial photodynamic therapy (PDT) and diffuse optical tomography (DOT) was developed and tested in a phantom experiment. The system, which was compatible with the operating room (OR) environment, had 16 channels for independent positioning of light sources and/or isotropic detectors in separate catheters. Each channel’s motor had an optical encoder for position feedback, with resolution of 1.5 mm, and a maximum speed of 5 cm/s. Automatic calibration of detector positions was implemented using an optical diode beam that defined the starting position of each motor, and by means of feedback algorithms controlling individual channels. As a result, the accuracy of zero position of 0.1 mm for all channels was achieved. We have also employed scanning procedures where detectors automatically covered the appropriate range around source positions. Thus, total scan time for a typical optical properties (OP) measurement throughout the phantom was about 1.5 minutes with point sources. The OP were determined based on the measured light fluence rates. These enhancements allow a tremendous improvement of treatment quality for a bulk tumor compared to the systems employed in previous clinical trials. PMID:25914794

  10. Parallel encryption for multi-channel images based on an optical joint transform correlator

    NASA Astrophysics Data System (ADS)

    Liu, Jie; Bai, Tingzhu; Shen, Xueju; Dou, Shuaifeng; Lin, Chao; Cai, Jianjun

    2017-08-01

    We propose an optical encryption method allowing the parallel encryption for multi-channel images based on a joint transform correlator (JTC). Distinguished from the conventional multi-image encryption methods, our proposed cryptosystem can encrypt multi-channel images simultaneously into a single ciphertext, which also can be used to recover arbitrary original images with corresponding keys. This method can achieve the compressed storage of ciphertext. In order to avoid the cross talk between multi-channel images, we restrict the respective joint power spectrum (JPS) into a specific area with optimized phase masks and split the multiple JPS by controlling the position of single JPS using the linear phase shifts. All of these operations are realized by optimizing and designing the phase masks which can be flexibly reconfigured on the spatial light modulator (SLM), leading to a feasible optical implementation with no increase of optical hardware and complexity. Computer simulations provide the validation for it. Experimental implementation is performed in a JTC-based cryptosystem to further verify the feasibility of our proposed method.

  11. Development of refined MCNPX-PARET multi-channel model for transient analysis in research reactors

    SciTech Connect

    Kalcheva, S.; Koonen, E.; Olson, A. P.

    2012-07-01

    Reactivity insertion transients are often analyzed (RELAP, PARET) using a two-channel model, representing the hot assembly with specified power distribution and an average assembly representing the remainder of the core. For the analysis of protected by the reactor safety system transients and zero reactivity feedback coefficients this approximation proves to give adequate results. However, a more refined multi-channel model representing the various assemblies, coupled through the reactivity feedback effects to the whole reactor core is needed for the analysis of unprotected transients with excluded over power and period trips. In the present paper a detailed multi-channel PARET model has been developed which describes the reactor core in different clusters representing typical BR2 fuel assemblies. The distribution of power and reactivity feedback in each cluster of the reactor core is obtained from a best-estimate MCNPX calculation using the whole core geometry model of the BR2 reactor. The sensitivity of the reactor response to power, temperature and energy distributions is studied for protected and unprotected reactivity insertion transients, with zero and non-zero reactivity feedback coefficients. The detailed multi-channel model is compared vs. simplified fewer-channel models. The sensitivities of transient characteristics derived from the different models are tested on a few reactivity insertion transients with reactivity feedback from coolant temperature and density change. (authors)

  12. An Interactive Visualization Tool for Multi-channel Confocal Microscopy Data in Neurobiology Research

    PubMed Central

    Wan, Yong; Otsuna, Hideo; Chien, Chi-Bin; Hansen, Charles

    2010-01-01

    Confocal microscopy is widely used in neurobiology for studying the three-dimensional structure of the nervous system. Confocal image data are often multi-channel, with each channel resulting from a different fluorescent dye or fluorescent protein; one channel may have dense data, while another has sparse; and there are often structures at several spatial scales: subneuronal domains, neurons, and large groups of neurons (brain regions). Even qualitative analysis can therefore require visualization using techniques and parameters fine-tuned to a particular dataset. Despite the plethora of volume rendering techniques that have been available for many years, the techniques standardly used in neurobiological research are somewhat rudimentary, such as looking at image slices or maximal intensity projections. Thus there is a real demand from neurobiologists, and biologists in general, for a flexible visualization tool that allows interactive visualization of multi-channel confocal data, with rapid fine-tuning of parameters to reveal the three-dimensional relationships of structures of interest. Together with neurobiologists, we have designed such a tool, choosing visualization methods to suit the characteristics of confocal data and a typical biologist’s workflow. We use interactive volume rendering with intuitive settings for multidimensional transfer functions, multiple render modes and multi-views for multi-channel volume data, and embedding of polygon data into volume data for rendering and editing. As an example, we apply this tool to visualize confocal microscopy datasets of the developing zebrafish visual system. PMID:19834225

  13. Load-adaptive practical multi-channel communications in wireless sensor networks.

    PubMed

    Islam, Md Shariful; Alam, Muhammad Mahbub; Hong, Choong Seon; Lee, Sungwon

    2010-01-01

    In recent years, a significant number of sensor node prototypes have been designed that provide communications in multiple channels. This multi-channel feature can be effectively exploited to increase the overall capacity and performance of wireless sensor networks (WSNs). In this paper, we present a multi-channel communications system for WSNs that is referred to as load-adaptive practical multi-channel communications (LPMC). LPMC estimates the active load of a channel at the sink since it has a more comprehensive view of the network behavior, and dynamically adds or removes channels based on the estimated load. LPMC updates the routing path to balance the loads of the channels. The nodes in a path use the same channel; therefore, they do not need to switch channels to receive or forward packets. LPMC has been evaluated through extensive simulations, and the results demonstrate that it can effectively increase the delivery ratio, network throughput, and channel utilization, and that it can decrease the end-to-end delay and energy consumption.

  14. Estimating neugebauer primaries for multi-channel spectral printing modeling

    NASA Astrophysics Data System (ADS)

    Slavuj, Radovan; Coppel, Ludovic G.; Olen, Melissa; Hardeberg, Jon Yngve

    2014-02-01

    Multichannel printer modeling has been an active area of research in the field of spectral printing. The most commonly used models for characterization of such systems are the spectral Neugebauer (SN) and its extensions. This work addresses issues that can arise during calibration and testing of the SN model when modelling a 7-colorant printer. Since most substrates are limited in their capacity to take in large amount of ink, it is not always possible to print all colorant combinations necessary to determine the Neugebauer primaries (NP). A common solution is to estimate the nonprintable Neugebauer primaries from the single colorant primaries using the Kubelka-Munk (KM) optical model. In this work we test whether a better estimate can be obtained using general radiative transfer theory, which better represents the angular variation of the reflectance from highly absorbing media, and takes surface scattering into account. For this purpose we use the DORT2002 model. We conclude DORT2002 does not offer significant improvements over KM in the estimation of the NPs, but a significant improvement is obtained when using a simple surface scattering model. When the estimated primaries are used as inputs to the SN model instead of measured ones, it is found the SN model performs the same or better in terms of color difference and spectral error. If the mixed measured and estimated primaries are used as inputs to the SN model, it performs better than using either measured or estimated.

  15. Nonlocal atlas-guided multi-channel forest learning for human brain labeling

    SciTech Connect

    Ma, Guangkai; Gao, Yaozong; Wu, Guorong; Wu, Ligang; Shen, Dinggang

    2016-02-15

    Purpose: It is important for many quantitative brain studies to label meaningful anatomical regions in MR brain images. However, due to high complexity of brain structures and ambiguous boundaries between different anatomical regions, the anatomical labeling of MR brain images is still quite a challenging task. In many existing label fusion methods, appearance information is widely used. However, since local anatomy in the human brain is often complex, the appearance information alone is limited in characterizing each image point, especially for identifying the same anatomical structure across different subjects. Recent progress in computer vision suggests that the context features can be very useful in identifying an object from a complex scene. In light of this, the authors propose a novel learning-based label fusion method by using both low-level appearance features (computed from the target image) and high-level context features (computed from warped atlases or tentative labeling maps of the target image). Methods: In particular, the authors employ a multi-channel random forest to learn the nonlinear relationship between these hybrid features and target labels (i.e., corresponding to certain anatomical structures). Specifically, at each of the iterations, the random forest will output tentative labeling maps of the target image, from which the authors compute spatial label context features and then use in combination with original appearance features of the target image to refine the labeling. Moreover, to accommodate the high inter-subject variations, the authors further extend their learning-based label fusion to a multi-atlas scenario, i.e., they train a random forest for each atlas and then obtain the final labeling result according to the consensus of results from all atlases. Results: The authors have comprehensively evaluated their method on both public LONI-LBPA40 and IXI datasets. To quantitatively evaluate the labeling accuracy, the authors use the

  16. Nonlocal atlas-guided multi-channel forest learning for human brain labeling

    PubMed Central

    Ma, Guangkai; Gao, Yaozong; Wu, Guorong; Wu, Ligang; Shen, Dinggang

    2016-01-01

    Purpose: It is important for many quantitative brain studies to label meaningful anatomical regions in MR brain images. However, due to high complexity of brain structures and ambiguous boundaries between different anatomical regions, the anatomical labeling of MR brain images is still quite a challenging task. In many existing label fusion methods, appearance information is widely used. However, since local anatomy in the human brain is often complex, the appearance information alone is limited in characterizing each image point, especially for identifying the same anatomical structure across different subjects. Recent progress in computer vision suggests that the context features can be very useful in identifying an object from a complex scene. In light of this, the authors propose a novel learning-based label fusion method by using both low-level appearance features (computed from the target image) and high-level context features (computed from warped atlases or tentative labeling maps of the target image). Methods: In particular, the authors employ a multi-channel random forest to learn the nonlinear relationship between these hybrid features and target labels (i.e., corresponding to certain anatomical structures). Specifically, at each of the iterations, the random forest will output tentative labeling maps of the target image, from which the authors compute spatial label context features and then use in combination with original appearance features of the target image to refine the labeling. Moreover, to accommodate the high inter-subject variations, the authors further extend their learning-based label fusion to a multi-atlas scenario, i.e., they train a random forest for each atlas and then obtain the final labeling result according to the consensus of results from all atlases. Results: The authors have comprehensively evaluated their method on both public LONI_LBPA40 and IXI datasets. To quantitatively evaluate the labeling accuracy, the authors use the

  17. Very Fast Algorithms and Detection Performance of Multi-Channel and 2-D Parametric Adaptive Matched Filters for Airborne Radar

    DTIC Science & Technology

    2007-06-05

    tive to the AMF, [1] and [5] discovered that multi-channel and two-dimensional parametric estimation approaches could (1) reduce the computational...dimensional (2-D) parametric estimation using the 2-D least-squares-based lattice algorithm [4]. The specifics of the inverse are found in the next...non- parametric estimation techniques • Least square error (LSE) vs mean square error (MSE) • Primarily multi-channel (M-C) structures; also try 2-D

  18. Multi-Channel Seismic Images of the Mariana Trough: EW0202 Initial Results

    NASA Astrophysics Data System (ADS)

    Taylor, B.; Goodliffe, A. M.; Moore, G. F.; Oakley, A. J.; Fryer, P.

    2002-12-01

    As the first major phase of a US-Japanese collaborative NSF-MARGINS funded project titled "Multi-scale seismic imaging of the Mariana Subduction factory", we collected 5124 km of multi-channel seismic (MCS) data between 14N and 19N across the Mariana subduction-arc-back-arc system. Using the R/V Maurice Ewing, we deployed a 6-km, 480-channel streamer and shot every 50 m using a 20-airgun array (6817 cu in). Coincident gravity, magnetic, and Hydrosweep DS2 data were collected on all 48 lines. The entire MCS dataset, with a common midpoint interval of 6.25 m, was processed through migration during the 30-day cruise. The resulting geophysical transects extend from the Pacific Plate, across the forearc (including several serpentine mud volcanoes), active arc and rifted margin, and back-arc spreading center to the remnant arc. The margins of the back-arc basin are irregular in plan form and contain arc salients that are almost surrounded by back-arc crust. Well-imaged, normal-fault bounded blocks are commonly juxtaposed against back-arc crust with few resolvable internal reflectors. A boundary of this type, with a prominent magnetic anomaly, is imaged on two MCS lines that cross the active arc south of Anatahan volcano at 16.2N. From the position of this boundary, to the east of the arc line, we infer that Anatahan is built on back-arc crust. This likely results in oceanic crust being sandwiched between arc extrusives and cumulates. Other active arc volcanoes may be built on or through rifted former-arc crust. Near 17.5N, 143.5E, an east-dipping low-angle normal fault (approximately 20 degree dip) is imaged beneath the graben at the boundary between the eastern edge of the West Mariana Ridge remnant arc and the oldest crust of the Mariana Trough. North of DSDP Site 451, on the rifted edge of the West Mariana Ridge, there are reflectors at 10-10.5 seconds two-way travel time that may be from the Moho. The back-arc spreading center has an hourglass-shaped inflated segment

  19. Multi-channel programmable power supply with temperature compensation for silicon sensors.

    PubMed

    Shukla, R A; Achanta, V G; Dugad, S R; Freeman, J; Garde, C S; Gupta, S K; Khandekar, P D; Kurup, A M; Lokhandwala, S S; Los, S; Prabhu, S S; Rakshe, P S

    2016-01-01

    Silicon Photo-Multipliers (SiPMs) are increasingly becoming popular for discrete photon counting applications due to the wealth of advantages they offer over conventional photo-detectors such as photo-multiplier tubes and hybrid photo-diodes. SiPMs are used in variety of applications ranging from high energy physics and nuclear physics experiments to medical diagnostics. The gain of a SiPM is directly proportional to the difference between applied and breakdown voltage of the device. However, the breakdown voltage depends critically on the ambient temperature and has a large temperature co-efficient in the range of 40-60 mV/°C resulting in a typical gain variation of 3%-5%/°C [Dinu et al., in IEEE Nuclear Science Symposium, Medical Imaging Conference and 17th Room Temperature Semiconductor Detector Workshop (IEEE, 2010), p. 215]. We plan to use the SiPM as a replacement for PMT in the cosmic ray experiment (GRAPES-3) at Ooty [Gupta et al., Nucl. Instrum. Methods Phys. Res., Sect. A 540, 311 (2005)]. There the SiPMs will be operated in an outdoor environment subjected to temperature variation of about 15 °C over a day. A gain variation of more than 50% was observed for such large variations in the temperature. To stabilize the gain of the SiPM under such operating conditions, a low-cost, multi-channel programmable power supply (0-90 V) was designed that simultaneously provides the bias voltage to 16 SiPMs. The programmable power supply (PPS) was designed to automatically adjust the operating voltage for each channel with a built-in closed loop temperature feedback mechanism. The PPS provides bias voltage with a precision of 6 mV and measures the load current with a precision of 1 nA. Using this PPS, a gain stability of 0.5% for SiPM (Hamamatsu, S10931-050P) has been demonstrated over a wide temperature range of 15 °C. The design methodology of the PPS system, its validation, and the results of the tests carried out on the SiPM is presented in this

  20. Multi-channel programmable power supply with temperature compensation for silicon sensors

    SciTech Connect

    Shukla, R. A.; Achanta, V. G.; Dugad, S. R. Kurup, A. M.; Lokhandwala, S. S.; Prabhu, S. S.; Freeman, J.; Los, S.; Garde, C. S.; Khandekar, P. D.; Gupta, S. K.; Rakshe, P. S.

    2016-01-15

    Silicon Photo-Multipliers (SiPMs) are increasingly becoming popular for discrete photon counting applications due to the wealth of advantages they offer over conventional photo-detectors such as photo-multiplier tubes and hybrid photo-diodes. SiPMs are used in variety of applications ranging from high energy physics and nuclear physics experiments to medical diagnostics. The gain of a SiPM is directly proportional to the difference between applied and breakdown voltage of the device. However, the breakdown voltage depends critically on the ambient temperature and has a large temperature co-efficient in the range of 40-60 mV/°C resulting in a typical gain variation of 3%-5%/°C [Dinu et al., in IEEE Nuclear Science Symposium, Medical Imaging Conference and 17th Room Temperature Semiconductor Detector Workshop (IEEE, 2010), p. 215]. We plan to use the SiPM as a replacement for PMT in the cosmic ray experiment (GRAPES-3) at Ooty [Gupta et al., Nucl. Instrum. Methods Phys. Res., Sect. A 540, 311 (2005)]. There the SiPMs will be operated in an outdoor environment subjected to temperature variation of about 15 °C over a day. A gain variation of more than 50% was observed for such large variations in the temperature. To stabilize the gain of the SiPM under such operating conditions, a low-cost, multi-channel programmable power supply (0-90 V) was designed that simultaneously provides the bias voltage to 16 SiPMs. The programmable power supply (PPS) was designed to automatically adjust the operating voltage for each channel with a built-in closed loop temperature feedback mechanism. The PPS provides bias voltage with a precision of 6 mV and measures the load current with a precision of 1 nA. Using this PPS, a gain stability of 0.5% for SiPM (Hamamatsu, S10931-050P) has been demonstrated over a wide temperature range of 15 °C. The design methodology of the PPS system, its validation, and the results of the tests carried out on the SiPM is presented in this

  1. Multi-channel programmable power supply with temperature compensation for silicon sensors

    NASA Astrophysics Data System (ADS)

    Shukla, R. A.; Achanta, V. G.; Dugad, S. R.; Freeman, J.; Garde, C. S.; Gupta, S. K.; Khandekar, P. D.; Kurup, A. M.; Lokhandwala, S. S.; Los, S.; Prabhu, S. S.; Rakshe, P. S.

    2016-01-01

    Silicon Photo-Multipliers (SiPMs) are increasingly becoming popular for discrete photon counting applications due to the wealth of advantages they offer over conventional photo-detectors such as photo-multiplier tubes and hybrid photo-diodes. SiPMs are used in variety of applications ranging from high energy physics and nuclear physics experiments to medical diagnostics. The gain of a SiPM is directly proportional to the difference between applied and breakdown voltage of the device. However, the breakdown voltage depends critically on the ambient temperature and has a large temperature co-efficient in the range of 40-60 mV/°C resulting in a typical gain variation of 3%-5%/°C [Dinu et al., in IEEE Nuclear Science Symposium, Medical Imaging Conference and 17th Room Temperature Semiconductor Detector Workshop (IEEE, 2010), p. 215]. We plan to use the SiPM as a replacement for PMT in the cosmic ray experiment (GRAPES-3) at Ooty [Gupta et al., Nucl. Instrum. Methods Phys. Res., Sect. A 540, 311 (2005)]. There the SiPMs will be operated in an outdoor environment subjected to temperature variation of about 15 °C over a day. A gain variation of more than 50% was observed for such large variations in the temperature. To stabilize the gain of the SiPM under such operating conditions, a low-cost, multi-channel programmable power supply (0-90 V) was designed that simultaneously provides the bias voltage to 16 SiPMs. The programmable power supply (PPS) was designed to automatically adjust the operating voltage for each channel with a built-in closed loop temperature feedback mechanism. The PPS provides bias voltage with a precision of 6 mV and measures the load current with a precision of 1 nA. Using this PPS, a gain stability of 0.5% for SiPM (Hamamatsu, S10931-050P) has been demonstrated over a wide temperature range of 15 °C. The design methodology of the PPS system, its validation, and the results of the tests carried out on the SiPM is presented in this article. The

  2. Simulation-based validation for four- dimensional multi-channel ultrasound current source density imaging.

    PubMed

    Wang, Zhaohui; Witte, Russell S

    2014-03-01

    Ultrasound current source density imaging (UCSDI), which has application to the heart and brain, exploits the acoustoelectric (AE) effect and Ohm's law to detect and map an electrical current distribution. In this study, we describe 4-D UCSDI simulations of a dipole field for comparison and validation with bench-top experiments. The simulations consider the properties of the ultrasound pulse as it passes through a conductive medium, the electric field of the injected dipole, and the lead field of the detectors. In the simulation, the lead fields of detectors and electric field of the dipole were calculated by the finite element (FE) method, and the convolution and correlation in the computation of the detected AE voltage signal were accelerated using 3-D fast Fourier transforms. In the bench-top experiment, an electric dipole was produced in a bath of 0.9% NaCl solution containing two electrodes, which injected an ac pulse (200 Hz, 3 cycles) ranging from 0 to 140 mA. Stimulating and recording electrodes were placed in a custom electrode chamber made on a rapid prototype printer. Each electrode could be positioned anywhere on an x-y grid (5 mm spacing) and individually adjusted in the depth direction for precise control of the geometry of the current sources and detecting electrodes. A 1-MHz ultrasound beam was pulsed and focused through a plastic film to modulate the current distribution inside the saline-filled tank. AE signals were simultaneously detected at a sampling frequency of 15 MHz on multiple recording electrodes. A single recording electrode is sufficient to form volume images of the current flow and electric potentials. The AE potential is sensitive to the distance from the dipole, but is less sensitive to the angle between the detector and the dipole. Multi-channel UCSDI potentially improves 4-D mapping of bioelectric sources in the body at high spatial resolution, which is especially important for diagnosing and guiding treatment of cardiac and

  3. Simulation-Based Validation for Four-Dimensional Multi-Channel Ultrasound Current Source Density Imaging

    PubMed Central

    Wang, Zhaohui; Witte, Russell S.

    2015-01-01

    Ultrasound current source density imaging (UCSDI), which has application to the heart and brain, exploits the acoustoelectric (AE) effect and Ohm's law to detect and map an electrical current distribution. In this study, we describe 4-D UCSDI simulations of a dipole field for comparison and validation with bench-top experiments. The simulations consider the properties of the ultrasound pulse as it passes through a conductive medium, the electric field of the injected dipole, and the lead field of the detectors. In the simulation, the lead fields of detectors and electric field of the dipole were calculated by the finite element (FE) method, and the convolution and correlation in the computation of the detected AE voltage signal were accelerated using 3-D fast Fourier transforms. In the bench-top experiment, an electric dipole was produced in a bath of 0.9% NaCl solution containing two electrodes, which injected an ac pulse (200 Hz, 3 cycles) ranging from 0 to 140 mA. Stimulating and recording electrodes were placed in a custom electrode chamber made on a rapid prototype printer. Each electrode could be positioned anywhere on an x-y grid (5 mm spacing) and individually adjusted in the depth direction for precise control of the geometry of the current sources and detecting electrodes. A 1-MHz ultrasound beam was pulsed and focused through a plastic film to modulate the current distribution inside the saline-filled tank. AE signals were simultaneously detected at a sampling frequency of 15 MHz on multiple recording electrodes. A single recording electrode is sufficient to form volume images of the current flow and electric potentials. The AE potential is sensitive to the distance from the dipole, but is less sensitive to the angle between the detector and the dipole. Multi-channel UCSDI potentially improves 4-D mapping of bioelectric sources in the body at high spatial resolution, which is especially important for diagnosing and guiding treatment of cardiac and

  4. Comparison of planform multi-channel network characteristics of alluvial and bedrock constrained large rivers

    NASA Astrophysics Data System (ADS)

    Carling, P. A.; Meshkova, L.; Robinson, R. A.

    2011-12-01

    The Mekong River in northern Cambodia is an multi-channel mixed bedrock-alluvial river but it was poorly researched until present. Preliminary study of the Mekong geomorphology was conducted by gathering existing knowledge of its geological and tectonic settings, specific riparian vegetation and ancient alluvial terraces in which the river has incised since the Holocene. Altogether this process has allowed a geomorphological portrait of the river to be composed within the Quaternary context. Following this outline, the planform characteristics of the Mekong River network are compared, using analysis of channel network and islands configurations, with the fluvial patterns of the Orange River (South Africa), Upper Columbia River (Canada) and the Ganga River (India, Bangladesh). These rivers are selected as examples of multi-channel mixed bedrock alluvial, anastomosed alluvial and braided alluvial rivers respectively. Network parameters such as channel bifurcation angles asymmetry, sinuosity, braid intensity and island morphometric shape metrics are compared and contrasted between bedrock and alluvial systems. In addition, regional and local topographic trend surfaces produced for each river planform help explain the local changes in river direction and the degree of anastomosis, and distinguish the bedrock-alluvial rivers from the alluvial rivers. Variations between planform characteristics are to be explained by channel forming processes and in the case of mixed bedrock-alluvial rivers mediated by structural control. Channel metrics (derived at the reach-scale) provide some discrimination between different multi-channel patterns but are not always robust when considered singly. In contrast, island shape metrics (obtained at subreach-scale) allow robust discrimination between alluvial and bedrock systems.

  5. A Multi-Channel Method for Detecting Periodic Forced Oscillations in Power Systems

    SciTech Connect

    Follum, James D.; Tuffner, Francis K.

    2016-11-14

    Forced oscillations in electric power systems are often symptomatic of equipment malfunction or improper operation. Detecting and addressing the cause of the oscillations can improve overall system operation. In this paper, a multi-channel method of detecting forced oscillations and estimating their frequencies is proposed. The method operates by comparing the sum of scaled periodograms from various channels to a threshold. A method of setting the threshold to specify the detector's probability of false alarm while accounting for the correlation between channels is also presented. Results from simulated and measured power system data indicate that the method outperforms its single-channel counterpart and is suitable for real-world applications.

  6. Note: Design principles of a linear array multi-channel effusive metal-vapor atom source

    SciTech Connect

    Jana, B.; Majumder, A.; Thakur, K. B.; Das, A. K.

    2013-10-15

    Atomic beams can easily be produced by allowing atoms to effuse through a channel. In an earlier investigation [A. Majumder et al., Vacuum 83, 989 (2009)], we had designed, fabricated, and characterized an effusive metal-vapor source using collinear-array of multi-channel. In this note, we describe the theoretical basis of designing the source. Atom density in atomic beam has been estimated using a set of analytical expressions for long-channel operated in transparent mode. Parametric studies on aspect ratio of channel, inter-channel separation, beam width, and vertical distance from the source are carried out. They are useful in providing physical picture and optimizing design parameters.

  7. A Beamforming Approach to Phase-Amplitude Modulation Analysis of Multi-Channel EEG

    PubMed Central

    Sampson, A.L.; Babadi, B.; Prerau, M.J.; Mukamel, E.A.; Brown, E.N.; Purdon, P.L.

    2013-01-01

    Phase-amplitude modulation is a form of cross frequency coupling where the phase of one frequency influences the amplitude of another higher frequency. It has been observed in neurophysiological recordings during sensory, motor, and cognitive tasks, as well as during general anesthesia. In this paper, we describe a novel beamforming procedure to improve estimation of phase-amplitude modulation. We apply this method to 64-channel EEG data recorded during propofol general anesthesia. The method improves the sensitivity of phase-amplitude analyses, and can be applied to a variety of multi-channel neuroscience data where phase-amplitude modulation is present. PMID:23367474

  8. Note: An underwater multi-channel plasma array for water sterilization

    NASA Astrophysics Data System (ADS)

    Yang, Y.; Kim, H.; Starikovskiy, A.; Cho, Y. I.; Fridman, A.

    2011-09-01

    A simple yet effective method to generate multi-channel plasma array in water is presented in this paper. Thin circular metal disks sandwiched between dielectric layers were used, allowing the production of large-volume underwater plasma array with higher stability. The system can be further scaled up by stacking multiple metal disks, making it suitable for large-scale industrial water treatment. Generation of UV and reactive species was identified by optical emission spectroscopy. Sterilization experiments were performed. Results show that the device was effective in deactivating E. coli in water over a wide range of initial concentrations ranging from 104 to 108 CFU/ml.

  9. Reprocessing of multi-channel seismic-reflection data collected in the Chukchi Sea

    USGS Publications Warehouse

    Agena, W.F.; Lee, M.W.; Hart, P.E.

    2001-01-01

    Contained on this set of two CD-ROMs are stacked and migrated multi-channel seismic-reflection data for 44 lines recorded in the Chukchi Sea, northern Alaska, by the United States Geological Survey in 1977, 1978, and 1980. All data were reprocessed by the USGS in 2000 using updated methods. The resulting final data have both increased temporal and spatial resolution thus providing improved interpretability. An added benefit of these CD-ROMs is that they are a more stable, long-term archival medium for the data.

  10. Pre-experiment testing of the Multi Channel Systems 16-channel preamplifier CPA16

    SciTech Connect

    Patin, J B; Stoyer, M A; Moody, K J; Friensehner, A V

    2003-11-03

    The 16-channel preamplifier model CPA16 from Multi Channel Systems was studied. The CPA16 preamplifier/amplifier module is a candidate to be used as the preamplifiers and amplifiers for the focal plane detectors of the Mass Analyzer of Super Heavy Atoms (MASHA). The equipment used to test the CPA16, the results of testing the CPA16 with a pulser, a mixed {sup 229}Th/{sup 148}Gd source and a {sup 252}Cf source, and a summary of the results will be presented.

  11. Investigation of ultra wideband multi-channel dichroic beamsplitters from 0.3 to 52 microns

    NASA Technical Reports Server (NTRS)

    Zhang, K. Q.; Hunneman, R.; Seeley, J. S.; Hawkins, G. J.

    1990-01-01

    The development of a set of multi-channel dichroics which includes a 6 channel dichroic operating over the wavelength region from 0.3 to 52 microns is described. In order to achieve the optimum performance, the optical constraints of PbTe, Ge, and CdTe coatings in the strongly absorptive region have been determined by use of a new iterative method using normal incidence reflectance measurement of the multilayer together with initial values of energy gap and infinite refractive index for the semiconductor model. The design and manufacture of the dichroics is discussed and the final results are presented.

  12. Joint MR-PET Reconstruction Using a Multi-Channel Image Regularizer.

    PubMed

    Knoll, Florian; Holler, Martin; Koesters, Thomas; Otazo, Ricardo; Bredies, Kristian; Sodickson, Daniel K

    2017-01-01

    While current state of the art MR-PET scanners enable simultaneous MR and PET measurements, the acquired data sets are still usually reconstructed separately. We propose a new multi-modality reconstruction framework using second order Total Generalized Variation (TGV) as a dedicated multi-channel regularization functional that jointly reconstructs images from both modalities. In this way, information about the underlying anatomy is shared during the image reconstruction process while unique differences are preserved. Results from numerical simulations and in-vivo experiments using a range of accelerated MR acquisitions and different MR image contrasts demonstrate improved PET image quality, resolution, and quantitative accuracy.

  13. Multi-channel beam-scanning imaging at kHz frame rates by Lissajous trajectory microscopy

    NASA Astrophysics Data System (ADS)

    Newman, Justin A.; Sullivan, Shane Z.; Muir, Ryan D.; Sreehari, Suhas; Bouman, Charles A.; Simpson, Garth J.

    2015-03-01

    A beam-scanning microscope based on Lissajous trajectory imaging is described for achieving streaming 2D imaging with continuous frame rates up to 1.4 kHz. The microscope utilizes two fast-scan resonant mirrors to direct the optical beam on a circuitous trajectory through the field of view. By separating the full Lissajous trajectory time-domain data into sub-trajectories (partial, undersampled trajectories) effective frame-rates much higher than the repeat time of the Lissajous trajectory are achieved with many unsampled pixels present. A model-based image reconstruction (MBIR) 3D in-painting algorithm is then used to interpolate the missing data for the unsampled pixels to recover full images. The MBIR algorithm uses a maximum a posteriori estimation with a generalized Gaussian Markov random field prior model for image interpolation. Because images are acquired using photomultiplier tubes or photodiodes, parallelization for multi-channel imaging is straightforward. Preliminary results show that when combined with the MBIR in-painting algorithm, this technique has the ability to generate kHz frame rate images across 6 total dimensions of space, time, and polarization for SHG, TPEF, and confocal reflective birefringence data on a multimodal imaging platform for biomedical imaging. The use of a multichannel data acquisition card allows for multimodal imaging with perfect image overlay. Image blur due to sample motion was also reduced by using higher frame rates.

  14. Multi-Channel Seismic Images of Neogene Rifting in the Northern Mona Passage Between Puerto Rico and Hispaniola

    NASA Astrophysics Data System (ADS)

    Mondziel, S. A.; Grindlay, N. R.; Mann, P.; Escalona, A.

    2006-12-01

    Highly oblique (70°) convergence is occurring along the northeastern North America-Caribbean plate boundary offshore northern Puerto Rico and the Virgin Islands. Complicating the tectonic setting is the oblique collision of the 20 km-thick SE Bahamas carbonate platform that impedes the northeasterly movement of Hispaniola, leaving Puerto Rico and the Virgin Islands to separate along north-trending extensional structures in the Mona Passage. Over 220 km of multi-channel seismic data collected in 1995 on the R/V Maurice Ewing were processed to investigate the geometry and timing of the opening of the Mona Canyon, a 20-30-km-wide, 120-km-long, and 2-3-km-deep basinal feature within the northern Mona Passage and Puerto Rico trench. Multibeam bathymetry and sidescan sonar data were combined with the profile data to evaluate the activity of faults at the seafloor. These data reveal that the Mona Canyon is underlain by a half-graben structure that is imaged to 5.5 seconds two-way travel time (stwt), ~11 km below seafloor (bsf). The master fault bounding the eastern edge of the canyon forms a continuous fault over a distance of tens of kms, exhibits a throw of up to 5 stwt, and dips an average of 70° to the west. An antithetic fault forms the western edge of the Mona Canyon, can also be traced for tens of kms, exhibits a throw of up to 2 stwt, and has a large slump deposit along its base. The history and kinematics of fault motions can be deduced from the late Oligocene-Pliocene carbonate platform present on both sides of the faulted Mona Canyon. To the east (footwall of the master fault), the carbonate platform is ~0.7 km thick and horizontal. To the west (footwall of the antithetic normal fault) the platform is twice as thick (~1.4 km) and also horizontal. The thicker platform section to the west indicates that space was created by sub-horizontal sliding along the listric master fault at depth; the thinner platform section to the east suggests that this area was the

  15. Multi-channel, fiber-based seed pulse distribution system for femtosecond-level synchronized chirped pulse amplifiers

    NASA Astrophysics Data System (ADS)

    Horáček, Martin; Indra, Lukáš; Green, Jonathan T.; Naylon, Jack A.; Tykalewicz, Boguslaw; Novák, Jakub; Batysta, František; Mazanec, Tomáš; Horáček, Jakub; Antipenkov, Roman; Hubka, Zbyněk; Boge, Robert; Bakule, Pavel; Rus, Bedřich

    2017-01-01

    We report on the design and performance of a fiber-based, multi-channel laser amplifier seed pulse distribution system. The device is designed to condition and distribute low energy laser pulses from a mode-locked oscillator to multiple, highly synchronized, high energy amplifiers integrated into a laser beamline. Critical functions such as temporal pulse stretching well beyond 100 ps/nm, pulse picking, and fine control over the pulse delay up to 300 ps are all performed in fiber eliminating the need for bulky and expensive grating stretchers, Pockels cells, and delay lines. These functions are characterized and the system as a whole is demonstrated by seeding two high energy amplifiers in the laser beamline. The design of this system allows for complete computer control of all functions, including tuning of dispersion, and is entirely hands-free. The performance of this device and its subsystems will be relevant to those developing lasers where reliability, size, and cost are key concerns in addition to performance; this includes those developing large-scale laser systems similar to ours and also those developing table-top experiments and commercial systems.

  16. Multi-channel, fiber-based seed pulse distribution system for femtosecond-level synchronized chirped pulse amplifiers.

    PubMed

    Horáček, Martin; Indra, Lukáš; Green, Jonathan T; Naylon, Jack A; Tykalewicz, Boguslaw; Novák, Jakub; Batysta, František; Mazanec, Tomáš; Horáček, Jakub; Antipenkov, Roman; Hubka, Zbyněk; Boge, Robert; Bakule, Pavel; Rus, Bedřich

    2017-01-01

    We report on the design and performance of a fiber-based, multi-channel laser amplifier seed pulse distribution system. The device is designed to condition and distribute low energy laser pulses from a mode-locked oscillator to multiple, highly synchronized, high energy amplifiers integrated into a laser beamline. Critical functions such as temporal pulse stretching well beyond 100 ps/nm, pulse picking, and fine control over the pulse delay up to 300 ps are all performed in fiber eliminating the need for bulky and expensive grating stretchers, Pockels cells, and delay lines. These functions are characterized and the system as a whole is demonstrated by seeding two high energy amplifiers in the laser beamline. The design of this system allows for complete computer control of all functions, including tuning of dispersion, and is entirely hands-free. The performance of this device and its subsystems will be relevant to those developing lasers where reliability, size, and cost are key concerns in addition to performance; this includes those developing large-scale laser systems similar to ours and also those developing table-top experiments and commercial systems.

  17. Cross contrast multi-channel image registration using image synthesis for MR brain images.

    PubMed

    Chen, Min; Carass, Aaron; Jog, Amod; Lee, Junghoon; Roy, Snehashis; Prince, Jerry L

    2017-02-01

    Multi-modal deformable registration is important for many medical image analysis tasks such as atlas alignment, image fusion, and distortion correction. Whereas a conventional method would register images with different modalities using modality independent features or information theoretic metrics such as mutual information, this paper presents a new framework that addresses the problem using a two-channel registration algorithm capable of using mono-modal similarity measures such as sum of squared differences or cross-correlation. To make it possible to use these same-modality measures, image synthesis is used to create proxy images for the opposite modality as well as intensity-normalized images from each of the two available images. The new deformable registration framework was evaluated by performing intra-subject deformation recovery, intra-subject boundary alignment, and inter-subject label transfer experiments using multi-contrast magnetic resonance brain imaging data. Three different multi-channel registration algorithms were evaluated, revealing that the framework is robust to the multi-channel deformable registration algorithm that is used. With a single exception, all results demonstrated improvements when compared against single channel registrations using the same algorithm with mutual information. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Omnidirectional and multi-channel filtering by photonic quantum wells with negative-index materials.

    PubMed

    Lin, Mi; Ouyang, Zhengbiao; Xu, Jun; Qiu, Gaoxin

    2009-03-30

    We propose a type of photonic quantum well made of two different photonic crystals with negative- and positive-index materials. It is demonstrated by transfer matrix method that, omnidirectional and multichannel filtering can be achieved. Resonance tunneling modes, or the multi-channel filtering modes, are found to exist when a passband of the well photonic crystal is located inside the gap of the barrier photonic crystals. And for each passband of the well photonic crystal in the photonic bandgap of the barrier photonic crystal, the number of modes is the same as the number of periods in the well photonic crystals. Moreover, the modes are insensitive to the incident angle from 0 to 85 degrees and the scaling of the barrier photonic crystals at a certain range. Such structures are useful for all-direction receiving, sending, or linking-up of multi-channel signals in wireless-communication networks. And they can be applied in signal-detection systems to enhance signal-detection sensitivity.

  19. SVM-Based Spectral Analysis for Heart Rate from Multi-Channel WPPG Sensor Signals.

    PubMed

    Xiong, Jiping; Cai, Lisang; Wang, Fei; He, Xiaowei

    2017-03-03

    Although wrist-type photoplethysmographic (hereafter referred to as WPPG) sensor signals can measure heart rate quite conveniently, the subjects' hand movements can cause strong motion artifacts, and then the motion artifacts will heavily contaminate WPPG signals. Hence, it is challenging for us to accurately estimate heart rate from WPPG signals during intense physical activities. The WWPG method has attracted more attention thanks to the popularity of wrist-worn wearable devices. In this paper, a mixed approach called Mix-SVM is proposed, it can use multi-channel WPPG sensor signals and simultaneous acceleration signals to measurement heart rate. Firstly, we combine the principle component analysis and adaptive filter to remove a part of the motion artifacts. Due to the strong relativity between motion artifacts and acceleration signals, the further denoising problem is regarded as a sparse signals reconstruction problem. Then, we use a spectrum subtraction method to eliminate motion artifacts effectively. Finally, the spectral peak corresponding to heart rate is sought by an SVM-based spectral analysis method. Through the public PPG database in the 2015 IEEE Signal Processing Cup, we acquire the experimental results, i.e., the average absolute error was 1.01 beat per minute, and the Pearson correlation was 0.9972. These results also confirm that the proposed Mix-SVM approach has potential for multi-channel WPPG-based heart rate estimation in the presence of intense physical exercise.

  20. SVM-Based Spectral Analysis for Heart Rate from Multi-Channel WPPG Sensor Signals

    PubMed Central

    Xiong, Jiping; Cai, Lisang; Wang, Fei; He, Xiaowei

    2017-01-01

    Although wrist-type photoplethysmographic (hereafter referred to as WPPG) sensor signals can measure heart rate quite conveniently, the subjects’ hand movements can cause strong motion artifacts, and then the motion artifacts will heavily contaminate WPPG signals. Hence, it is challenging for us to accurately estimate heart rate from WPPG signals during intense physical activities. The WWPG method has attracted more attention thanks to the popularity of wrist-worn wearable devices. In this paper, a mixed approach called Mix-SVM is proposed, it can use multi-channel WPPG sensor signals and simultaneous acceleration signals to measurement heart rate. Firstly, we combine the principle component analysis and adaptive filter to remove a part of the motion artifacts. Due to the strong relativity between motion artifacts and acceleration signals, the further denoising problem is regarded as a sparse signals reconstruction problem. Then, we use a spectrum subtraction method to eliminate motion artifacts effectively. Finally, the spectral peak corresponding to heart rate is sought by an SVM-based spectral analysis method. Through the public PPG database in the 2015 IEEE Signal Processing Cup, we acquire the experimental results, i.e., the average absolute error was 1.01 beat per minute, and the Pearson correlation was 0.9972. These results also confirm that the proposed Mix-SVM approach has potential for multi-channel WPPG-based heart rate estimation in the presence of intense physical exercise. PMID:28273818

  1. Application of a multi-channel system for continuous monitoring and an early warning system.

    PubMed

    Lee, J H; Song, C H; Kim, B C; Gu, M B

    2006-01-01

    A multi-channel continuous toxicity monitoring system developed in our laboratory, based on two-stage mini-bioreactors, was successfully implemented in the form of computer-based data acquisition. The multi-channel system consists of a series of a two-stage minibioreactor systems connected by a fiber optic probe to a luminometer, and uses genetically engineered bioluminescent bacteria for the detection of the potential toxicity from the soluble chemicals. This system can be stably and continuously operated due to the separation of the culture reactor from the test reactor and accomplish easy and long-term monitoring without system shut down by abrupt inflows of severe polluting chemicals. Four different recombinant bioluminescent bacteria were used in different channels so that the modes of the samples toxicities can be reasonably identified and evaluated based upon the response signature of each channel. The bioluminescent signatures were delivered from four channels by switching one at once, while the data is automatically logged to an IBM compatible computer. We also achieved the enhancement of the system through the manipulation of the dilution rate and the use of thermo-lux fusion strains. Finally, this system is now being implemented to a drinking water reservoir and river for remote sensing as an early warning system.

  2. A schedule-based multi-channel MAC protocol for wireless sensor networks.

    PubMed

    Hamid, Md Abdul; Abdullah-Al-Wadud, M; Chong, Ilyoung

    2010-01-01

    Due to the half-duplex property of the sensor radio and the broadcast nature of wireless medium, limited bandwidth remains a pressing issue for wireless sensor networks (WSNs). The design of multi-channel MAC protocols has attracted the interest of many researchers as a cost effective solution to meet the higher bandwidth demand for the limited bandwidth in WSN. In this paper, we present a scheduled-based multi-channel MAC protocol to improve network performance. In our protocol, each receiving node selects (schedules) some timeslot(s), in which it may receive data from the intending sender(s). The timeslot selection is done in a conflict free manner, where a node avoids the slots that are already selected by others in its interference range. To minimize the conflicts during timeslot selection, we propose a unique solution by splitting the neighboring nodes into different groups, where nodes of a group may select the slots allocated to that group only. We demonstrate the effectiveness of our approach thorough simulations in terms of performance parameters such as aggregate throughput, packet delivery ratio, end-to-end delay, and energy consumption.

  3. Robust detection of multiple sclerosis lesions from intensity-normalized multi-channel MRI

    NASA Astrophysics Data System (ADS)

    Karpate, Yogesh; Commowick, Olivier; Barillot, Christian

    2015-03-01

    Multiple sclerosis (MS) is a disease with heterogeneous evolution among the patients. Quantitative analysis of longitudinal Magnetic Resonance Images (MRI) provides a spatial analysis of the brain tissues which may lead to the discovery of biomarkers of disease evolution. Better understanding of the disease will lead to a better discovery of pathogenic mechanisms, allowing for patient-adapted therapeutic strategies. To characterize MS lesions, we propose a novel paradigm to detect white matter lesions based on a statistical framework. It aims at studying the benefits of using multi-channel MRI to detect statistically significant differences between each individual MS patient and a database of control subjects. This framework consists in two components. First, intensity standardization is conducted to minimize the inter-subject intensity difference arising from variability of the acquisition process and different scanners. The intensity normalization maps parameters obtained using a robust Gaussian Mixture Model (GMM) estimation not affected by the presence of MS lesions. The second part studies the comparison of multi-channel MRI of MS patients with respect to an atlas built from the control subjects, thereby allowing us to look for differences in normal appearing white matter, in and around the lesions of each patient. Experimental results demonstrate that our technique accurately detects significant differences in lesions consequently improving the results of MS lesion detection.

  4. Developmental changes in frontal lobe function during a verbal fluency task: a multi-channel near-infrared spectroscopy study.

    PubMed

    Tando, Tomoko; Kaga, Yoshimi; Ishii, Sayaka; Aoyagi, Kakuro; Sano, Fumikazu; Kanemura, Hideaki; Sugita, Kanji; Aihara, Masao

    2014-11-01

    Near-infrared spectroscopy (NIRS) is commonly used to investigate continuous changes of brain activation and has excellent time resolution. Verbal fluency task (VFT) is widely used as a neuropsychological test of frontal lobe function. The aim of this study was to investigate normal developmental change in frontal lobe function during VFT performance using multi-channel NIRS, specifically focusing on oxygenation hemoglobin (oxyHb) changes. The subjects were 9 adults and 37 childrens who were all healthy right-handed volunteers. Children were divided into four age groups (group A, 6-8 years; group B, 9-11 years; group C, 12-14 years; group D, 15-18 years). The [oxyHb] changes were measured with 22 channels of NIRS during VFT. We defined the frontopolar region as the region of interest for analysis, and calculated the Z-score to compare the data between groups. The task performance changed with age. There were significant differences between group A and other groups. The Z-score of [oxyHb] also significantly increased with age, when comparing adults to groups A and B. The task performances decreased with time in all groups. In contrast, [oxyHb] only continued to increase in the adult group. The verbal retrieval functions begin to mature in early adolescence and continue to grow up to adulthood. Copyright © 2014 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  5. Characterization of 3D MEMS structural dynamics with a conformal multi-channel fiber optic heterodyne vibrometer

    NASA Astrophysics Data System (ADS)

    Kilpatrick, James; Apostol, Adela; Markov, Vladimir

    Insight into transient structural interactions, including coupled vibrations and modal non-degeneracy (mode splitting) is important to the development of current and next generation vibratory gyroscopes and MEMS resonators. Device optimization based on characterization of these effects is currently time consuming and limited by the requirement to perform spatially distributed measurements with existing single point sensors. In addition, the effects of interest and the diagnosis of their underlying causes and dependences are not readily revealed by traditional modal and finite element analyses. This paper, accordingly, discusses the design of a novel multi-channel fiber-optic heterodyne vibrometer which addresses this requirement directly. We describe a fiber-optic interferometer design which incorporates many standard fiber-optic telecommunications components, configured to support dynamic imaging of the real-time structural behavior of macro and micro vibratory resonators, including planar and 3D micro electromechanical systems (MEMS). The capabilities of the new sensor are illustrated by representative data obtained from a variety of 3D vibratory MEMS structures currently under development.

  6. Linear and nonlinear analyses of multi-channel mechanomyographic recordings reveal heterogeneous activation of wrist extensors in presence of delayed onset muscle soreness.

    PubMed

    Madeleine, Pascal; Hansen, Ernst A; Samani, Afshin

    2014-12-01

    In this study, we applied multi-channel mechanomyographic (MMG) recordings in combination with linear and nonlinear analyses to investigate muscular and musculotendinous effects of high intensity eccentric exercise. Twelve accelerometers arranged in a 3 × 4 matrix over the dominant elbow muscles were used to detect MMG activity in 12 healthy participants. Delayed onset muscle soreness was induced by repetitive high intensity eccentric contractions of the wrist extensor muscles. Average rectified values (ARV) as well as percentage of recurrence (%REC) and percentage of determinism (%DET) extracted from recurrence quantification analysis were computed from data obtained during static-dynamic contractions performed before exercise, immediately after exercise, and in presence of muscle soreness. A linear mixed model was used for the statistical analysis. The ARV, %REC, and %DET maps revealed heterogeneous MMG activity over the wrist extensor muscles before, immediately after, and in presence of muscle soreness (P<0.01). The ARVs were higher while the %REC and %DET were lower in presence of muscle soreness compared with before exercise (P<0.05). The study provides new key information on linear and nonlinear analyses of multi-channel MMG recordings of the wrist extensor muscles following eccentric exercise that results in muscle soreness. Recurrence quantification analysis can be suggested as a tool for detection of MMG changes in presence of muscle soreness.

  7. BDNF gene delivery within and beyond templated agarose multi-channel guidance scaffolds enhances peripheral nerve regeneration

    NASA Astrophysics Data System (ADS)

    Gao, Mingyong; Lu, Paul; Lynam, Dan; Bednark, Bridget; Campana, W. Marie; Sakamoto, Jeff; Tuszynski, Mark

    2016-12-01

    Objective. We combined implantation of multi-channel templated agarose scaffolds with growth factor gene delivery to examine whether this combinatorial treatment can enhance peripheral axonal regeneration through long sciatic nerve gaps. Approach. 15 mm long scaffolds were templated into highly organized, strictly linear channels, mimicking the linear organization of natural nerves into fascicles of related function. Scaffolds were filled with syngeneic bone marrow stromal cells (MSCs) secreting the growth factor brain derived neurotrophic factor (BDNF), and lentiviral vectors expressing BDNF were injected into the sciatic nerve segment distal to the scaffold implantation site. Main results. Twelve weeks after injury, scaffolds supported highly linear regeneration of host axons across the 15 mm lesion gap. The incorporation of BDNF-secreting cells into scaffolds significantly increased axonal regeneration, and additional injection of viral vectors expressing BDNF into the distal segment of the transected nerve significantly enhanced axonal regeneration beyond the lesion. Significance. Combinatorial treatment with multichannel bioengineered scaffolds and distal growth factor delivery significantly improves peripheral nerve repair, rivaling the gold standard of autografts.

  8. High Accuracy Time Transfer Synchronization

    DTIC Science & Technology

    1994-12-01

    HIGH ACCURACY TIME TRANSFER SYNCHRONIZATION Paul Wheeler, Paul Koppang, David Chalmers, Angela Davis, Anthony Kubik and William Powell U.S. Naval...Observatory Washington, DC 20392 Abstract In July 1994, the US Naval Observatory (USNO) Time Service System Engineering Division conducted a...field test to establish a baseline accuracy for two-way satellite time transfer synchro- nization. Three Hewlett-Packard model 5071 high performance

  9. Do you see what I hear: experiments in multi-channel sound and 3D visualization for network monitoring?

    NASA Astrophysics Data System (ADS)

    Ballora, Mark; Hall, David L.

    2010-04-01

    Detection of intrusions is a continuing problem in network security. Due to the large volumes of data recorded in Web server logs, analysis is typically forensic, taking place only after a problem has occurred. This paper describes a novel method of representing Web log information through multi-channel sound, while simultaneously visualizing network activity using a 3-D immersive environment. We are exploring the detection of intrusion signatures and patterns, utilizing human aural and visual pattern recognition ability to detect intrusions as they occur. IP addresses and return codes are mapped to an informative and unobtrusive listening environment to act as a situational sound track of Web traffic. Web log data is parsed and formatted using Python, then read as a data array by the synthesis language SuperCollider [1], which renders it as a sonification. This can be done either for the study of pre-existing data sets or in monitoring Web traffic in real time. Components rendered aurally include IP address, geographical information, and server Return Codes. Users can interact with the data, speeding or slowing the speed of representation (for pre-existing data sets) or "mixing" sound components to optimize intelligibility for tracking suspicious activity.

  10. A multi-channel opto-electronic sensor to accurately monitor heart rate against motion artefact during exercise.

    PubMed

    Alzahrani, Abdullah; Hu, Sijung; Azorin-Peris, Vicente; Barrett, Laura; Esliger, Dale; Hayes, Matthew; Akbare, Shafique; Achart, Jérôme; Kuoch, Sylvain

    2015-10-12

    This study presents the use of a multi-channel opto-electronic sensor (OEPS) to effectively monitor critical physiological parameters whilst preventing motion artefact as increasingly demanded by personal healthcare. The aim of this work was to study how to capture the heart rate (HR) efficiently through a well-constructed OEPS and a 3-axis accelerometer with wireless communication. A protocol was designed to incorporate sitting, standing, walking, running and cycling. The datasets collected from these activities were processed to elaborate sport physiological effects. t-test, Bland-Altman Agreement (BAA), and correlation to evaluate the performance of the OEPS were used against Polar and Mio-Alpha HR monitors. No differences in the HR were found between OEPS, and either Polar or Mio-Alpha (both p > 0.05); a strong correlation was found between Polar and OEPS (r: 0.96, p < 0.001); the bias of BAA 0.85 bpm, the standard deviation (SD) 9.20 bpm, and the limits of agreement (LOA) from -17.18 bpm to +18.88 bpm. For the Mio-Alpha and OEPS, a strong correlation was found (r: 0.96, p < 0.001); the bias of BAA 1.63 bpm, SD 8.62 bpm, LOA from -15.27 bpm to +18.58 bpm. These results demonstrate the OEPS to be capable of carrying out real time and remote monitoring of heart rate.

  11. Research on multi - channel interactive virtual assembly system for power equipment under the “VR+” era

    NASA Astrophysics Data System (ADS)

    Ren, Yilong; Duan, Xitong; Wu, Lei; He, Jin; Xu, Wu

    2017-06-01

    With the development of the “VR+” era, the traditional virtual assembly system of power equipment has been unable to satisfy our growing needs. In this paper, based on the analysis of the traditional virtual assembly system of electric power equipment and the application of VR technology in the virtual assembly system of electric power equipment in our country, this paper puts forward the scheme of establishing the virtual assembly system of power equipment: At first, we should obtain the information of power equipment, then we should using OpenGL and multi texture technology to build 3D solid graphics library. After the completion of three-dimensional modeling, we can use the dynamic link library DLL package three-dimensional solid graphics generation program to realize the modularization of power equipment model library and power equipment model library generated hidden algorithm. After the establishment of 3D power equipment model database, we set up the virtual assembly system of 3D power equipment to separate the assembly operation of the power equipment from the space. At the same time, aiming at the deficiency of the traditional gesture recognition algorithm, we propose a gesture recognition algorithm based on improved PSO algorithm for BP neural network data glove. Finally, the virtual assembly system of power equipment can really achieve multi-channel interaction function.

  12. Comprehensive multi-channel multi-dimensional counter-current chromatography for separation of tanshinones from Salvia miltiorrhiza Bunge.

    PubMed

    Meng, Jie; Yang, Zhi; Liang, Junling; Zhou, Hui; Wu, Shihua

    2014-01-03

    Multi-dimensional chromatography offers the increased resolution and peak capacity by coupling of multiple columns with the same or different separation mechanisms. In this work, a novel multi-channel multi-dimensional counter-current chromatography (CCC) has been successfully constructed and used for several two-dimensional (2D) and three-dimensional (3D) CCC separations including 2D A×B/A×C, A×B-C and A-B×C, and 3D A×B×C systems. These 2D and 3D CCC systems were further applied to separate the bioactive tanshinones from the extract of Tanshen (or Danshen, Salvia miltiorrhiza Bunge), a famous Traditional Chinese Medicine (TCM). As a result, the developed 2D and 3D CCC methods were successful and efficient for resolving the tanshinones from complex extracts. Compared to the 1D multiple columns CCC separation, the 2D and 3D CCC decrease analysis time, reduce solvent consumption and increase sample throughput significantly. It may be widely used for current drug development, metabolomic analysis and natural product isolation.

  13. A Multi-Channel Opto-Electronic Sensor to Accurately Monitor Heart Rate against Motion Artefact during Exercise

    PubMed Central

    Alzahrani, Abdullah; Hu, Sijung; Azorin-Peris, Vicente; Barrett, Laura; Esliger, Dale; Hayes, Matthew; Akbare, Shafique; Achart, Jérôme; Kuoch, Sylvain

    2015-01-01

    This study presents the use of a multi-channel opto-electronic sensor (OEPS) to effectively monitor critical physiological parameters whilst preventing motion artefact as increasingly demanded by personal healthcare. The aim of this work was to study how to capture the heart rate (HR) efficiently through a well-constructed OEPS and a 3-axis accelerometer with wireless communication. A protocol was designed to incorporate sitting, standing, walking, running and cycling. The datasets collected from these activities were processed to elaborate sport physiological effects. t-test, Bland-Altman Agreement (BAA), and correlation to evaluate the performance of the OEPS were used against Polar and Mio-Alpha HR monitors. No differences in the HR were found between OEPS, and either Polar or Mio-Alpha (both p > 0.05); a strong correlation was found between Polar and OEPS (r: 0.96, p < 0.001); the bias of BAA 0.85 bpm, the standard deviation (SD) 9.20 bpm, and the limits of agreement (LOA) from −17.18 bpm to +18.88 bpm. For the Mio-Alpha and OEPS, a strong correlation was found (r: 0.96, p < 0.001); the bias of BAA 1.63 bpm, SD 8.62 bpm, LOA from −15.27 bpm to +18.58 bpm. These results demonstrate the OEPS to be capable of carrying out real time and remote monitoring of heart rate. PMID:26473860

  14. Calculation of BER in multi-channel silicon optical interconnects: comparative analysis of strip and photonic crystal waveguides

    NASA Astrophysics Data System (ADS)

    You, Jie; Lavdas, Spyros; Panoiu, Nicolae C.

    2016-05-01

    We present an effective approach to evaluate the performance of multi-channel silicon (Si) photonic systems. The system is composed of strip Si photonic waveguides (Si-PhWs) with uniform cross-section or photonic-crystal (PhC) Si waveguides (Si-PhCWs), combined with a set of direct-detection receivers. Moreover, the optical field in each channel is the superposition of a continuous-wave nonreturn-to-zero ON-OFF keying modulated signal and a white Gaussian noise. In order to characterize the optical signal propagation in the waveguides, an accurate mathematical model describing all relevant linear and nonlinear optical effects and its linearized version is employed. In addition, two semi-analytical methods, time- and frequency-domain Karhunen-Loève series expansion, are used to assess the system bit-error-rate (BER). Our analysis reveals that Si-PhCWs provide similar performance as Si-PhWs, but for 100× shorter length. Importantly, much worse BER is achieved in Si-PhCWs when one operates in slow-light regime, due to the enhanced linear and nonlinear effects.

  15. BioSigPlot: an opensource tool for the visualization of multi-channel biomedical signals with Matlab.

    PubMed

    Boudet, Samuel; Peyrodie, Laurent; Gallois, Philippe; de l'Aulnoit, Denis Houzé; Cao, Hua; Forzy, Gérard

    2013-01-01

    This paper presents a Matlab-based software (MathWorks inc.) called BioSigPlot for the visualization of multi-channel biomedical signals, particularly for the EEG. This tool is designed for researchers on both engineering and medicine who have to collaborate to visualize and analyze signals. It aims to provide a highly customizable interface for signal processing experimentation in order to plot several kinds of signals while integrating the common tools for physician. The main advantages compared to other existing programs are the multi-dataset displaying, the synchronization with video and the online processing. On top of that, this program uses object oriented programming, so that the interface can be controlled by both graphic controls and command lines. It can be used as EEGlab plug-in but, since it is not limited to EEG, it would be distributed separately. BioSigPlot is distributed free of charge (http://biosigplot.sourceforge.net), under the terms of GNU Public License for non-commercial use and open source development.

  16. Implementation of the multi-channel monolith reactor in an optimisation procedure for heterogeneous oxidation catalysts based on genetic algorithms.

    PubMed

    Breuer, Christian; Lucas, Martin; Schütze, Frank-Walter; Claus, Peter

    2007-01-01

    A multi-criteria optimisation procedure based on genetic algorithms is carried out in search of advanced heterogeneous catalysts for total oxidation. Simple but flexible software routines have been created to be applied within a search space of more then 150,000 individuals. The general catalyst design includes mono-, bi- and trimetallic compositions assembled out of 49 different metals and depleted on an Al2O3 support in up to nine amount levels. As an efficient tool for high-throughput screening and perfectly matched to the requirements of heterogeneous gas phase catalysis - especially for applications technically run in honeycomb structures - the multi-channel monolith reactor is implemented to evaluate the catalyst performances. Out of a multi-component feed-gas, the conversion rates of carbon monoxide (CO) and a model hydrocarbon (HC) are monitored in parallel. In combination with further restrictions to preparation and pre-treatment a primary screening can be conducted, promising to provide results close to technically applied catalysts. Presented are the resulting performances of the optimisation process for the first catalyst generations and the prospect of its auto-adaptation to specified optimisation goals.

  17. An online multi-channel SSVEP-based brain-computer interface using a canonical correlation analysis method.

    PubMed

    Bin, Guangyu; Gao, Xiaorong; Yan, Zheng; Hong, Bo; Gao, Shangkai

    2009-08-01

    In recent years, there has been increasing interest in using steady-state visual evoked potential (SSVEP) in brain-computer interface (BCI) systems. However, several aspects of current SSVEP-based BCI systems need improvement, specifically in relation to speed, user variation and ease of use. With these improvements in mind, this paper presents an online multi-channel SSVEP-based BCI system using a canonical correlation analysis (CCA) method for extraction of frequency information associated with the SSVEP. The key parameters, channel location, window length and the number of harmonics, are investigated using offline data, and the result used to guide the design of the online system. An SSVEP-based BCI system with six targets, which use nine channel locations in the occipital and parietal lobes, a window length of 2 s and the first harmonic, is used for online testing on 12 subjects. The results show that the proposed BCI system has a high performance, achieving an average accuracy of 95.3% and an information transfer rate of 58 +/- 9.6 bit min(-1). The positive characteristics of the proposed system are that channel selection and parameter optimization are not required, the possible use of harmonic frequencies, low user variation and easy setup.

  18. An online multi-channel SSVEP-based brain-computer interface using a canonical correlation analysis method

    NASA Astrophysics Data System (ADS)

    Bin, Guangyu; Gao, Xiaorong; Yan, Zheng; Hong, Bo; Gao, Shangkai

    2009-08-01

    In recent years, there has been increasing interest in using steady-state visual evoked potential (SSVEP) in brain-computer interface (BCI) systems. However, several aspects of current SSVEP-based BCI systems need improvement, specifically in relation to speed, user variation and ease of use. With these improvements in mind, this paper presents an online multi-channel SSVEP-based BCI system using a canonical correlation analysis (CCA) method for extraction of frequency information associated with the SSVEP. The key parameters, channel location, window length and the number of harmonics, are investigated using offline data, and the result used to guide the design of the online system. An SSVEP-based BCI system with six targets, which use nine channel locations in the occipital and parietal lobes, a window length of 2 s and the first harmonic, is used for online testing on 12 subjects. The results show that the proposed BCI system has a high performance, achieving an average accuracy of 95.3% and an information transfer rate of 58 ± 9.6 bit min-1. The positive characteristics of the proposed system are that channel selection and parameter optimization are not required, the possible use of harmonic frequencies, low user variation and easy setup.

  19. Improved version of the printed circuit board (PCB) modular multi-channel microdrive for extracellular electrophysiological recordings.

    PubMed

    Tóth, Attila; Petykó, Zoltán; Máthé, Kálmán; Szabó, Imre; Czurkó, András

    2007-01-15

    The modular multi-channel PCB microdrive was described some years ago, since then several improvements were introduced while using these drives. Utilizing several years of experience with the original PCB microdrive we redesigned it to improve its stability and usability. The application of the printed circuit board technology and the extensive use of flexible fused silica capillaries for fabrication of the microdrive are described in detail. The improved design led to a low cost and light-weight multi-channel microdrive with outstanding modularity for extracellular field, single unit or multiunit tetrode recording up to 64/128 channels.

  20. All-optical multi-channel wavelength conversion of Nyquist 16 QAM signal using a silicon waveguide.

    PubMed

    Long, Yun; Liu, Jun; Hu, Xiao; Wang, Andong; Zhou, Linjie; Zou, Kaiheng; Zhu, Yixiao; Zhang, Fan; Wang, Jian

    2015-12-01

    We experimentally demonstrate on-chip all-optical multi-channel wavelength conversion of Nyquist 16 ary quadrature amplitude modulation (16 QAM) signal in a silicon waveguide. The measured optical signal-to-noise ratio (OSNR) penalties of wavelength conversion are ∼2  dB. The observed constellations of converted idlers indicate favorable performance of silicon-waveguide-based multi-channel wavelength conversion. We also experimentally study and compare the phase-conjugated wavelength conversion by degenerate four-wave mixing (FWM) and transparent wavelength conversion by non-degenerate FWM in the silicon waveguide.

  1. Quantum and quasiclassical dynamics of the multi-channel H + H2S reaction

    NASA Astrophysics Data System (ADS)

    Qi, Ji; Lu, Dandan; Song, Hongwei; Li, Jun; Yang, Minghui

    2017-03-01

    The prototypical multi-channel reaction H + H2S → H2 + SH/H + H2S has been investigated using the full-dimensional quantum scattering and quasi-classical trajectory methods to unveil the underlying competition mechanism between different product channels and the mode specificity. This reaction favors the abstraction channel over the exchange channel. For both channels, excitations in the two stretching modes promote the reaction with nearly equal efficiency and are more efficient than the bending mode excitation. However, they are all less efficient than the translational energy. In addition, the experimentally observed non-Arrhenius temperature dependence of the thermal rate constants is reasonably reproduced by the quantum dynamics calculations, confirming that the non-Arrhenius behavior is caused by the pronounced quantum tunneling.

  2. Design of a multi-channel free space optical interconnection component

    NASA Astrophysics Data System (ADS)

    Jia, Da-Gong; Zhang, Pei-Song; Jing, Wen-Cai; Tan, Jun; Zhang, Hong-Xia; Zhang, Yi-Mo

    2008-11-01

    A multi-channel free space optical interconnection component, fiber optic rotary joint, was designed using a Dove prism. When the Dove prism is rotated an angle of α around the longitudinal axis, the image rotates an angle of 2 α. The optical interconnection component consists of the signal transmission system, Dove prim and driving mechanism. The planetary gears are used to achieve the speed ratio of 2:1 between the total optical interconnection component and the Dove prism. The C-lenses are employed to couple different optical signals in the signal transmission system. The coupling loss between the receiving fiber of stationary part and the transmitting fiber of rotary part is measured.

  3. Telephone speech enhancement for hearing-impaired listeners using multi-channel compression

    NASA Astrophysics Data System (ADS)

    Natarajan, Harikrishna P.; Krishnamurthy, Ashok K.; Feth, Lawrence L.

    2002-05-01

    Elderly listeners with sensorineural hearing impairment usually have difficulty with telephone communication if they do not use a hearing aid or telephone amplifier. In many cases, these devices may not be readily available or maybe uncomfortable to use. We describe here an alternative strategy to enhance the speech by pre-processing the signal before sending it over the telephone line. The pre-processing is based on a multi-channel compression algorithm that modifies the critical band spectrum of the speech signal to bring it within the dynamic hearing range of the listener, while also compensating for the effects of the telephone line. We describe the algorithm and the results of a simulation study in which the Articulation Index (AI) is used to measure the intelligibility enhancement, and the Glasberg, Moore and Stone (1999) model is used to simulate the effects of the hearing loss.

  4. Note: an underwater multi-channel plasma array for water sterilization.

    PubMed

    Yang, Y; Kim, H; Starikovskiy, A; Cho, Y I; Fridman, A

    2011-09-01

    A simple yet effective method to generate multi-channel plasma array in water is presented in this paper. Thin circular metal disks sandwiched between dielectric layers were used, allowing the production of large-volume underwater plasma array with higher stability. The system can be further scaled up by stacking multiple metal disks, making it suitable for large-scale industrial water treatment. Generation of UV and reactive species was identified by optical emission spectroscopy. Sterilization experiments were performed. Results show that the device was effective in deactivating E. coli in water over a wide range of initial concentrations ranging from 10(4) to 10(8) CFU/ml. © 2011 American Institute of Physics

  5. Design of a novel multi channel photonic crystal fiber polarization beam splitter

    NASA Astrophysics Data System (ADS)

    Zhao, Yunyan; Li, Shuguang; Wang, Xinyu; Wang, Guangyao; Shi, Min; Wu, Junjun

    2017-10-01

    A kind of multi channel dual-core photonic crystal fiber polarization beam splitter is designed. We analyze the effects of the lattice parameters and the thickness of gold layer on the beam splitting by the finite element method. Numerical results show that the thickness of metal layer and the size of the air holes near the fiber cores are closely linked with the nature of the polarization beam splitter. We also obtain that extinction ratio can reach -73.87 dB at 1 . 55 μm wavelength and at 1 . 41 μm, 1 . 65 μm extinction ratio can reach 30.8978 dB and 31.1741 dB, respectively. The comparison of the effect on the characteristic of the photonic crystal fiber with coating no gold is also taken into account.

  6. [Decoupling of multi-channel RF coil and its application in the intraoperative MRI].

    PubMed

    Xin, Xuegang; Han, Jijun; Feng, Yanqiu; Chen, Wufan

    2011-04-01

    The coupling from different elements of the multi-channel coil leads to the splitting of the resonance frequency and deviation from the Lamor frequency. Decoupling between different elements is the key technology in the design of the radiofrequency (RF) coil. The electrical decoupling circuits should vary with different arrangements of the elements. A novel method of decoupling for the RF coil used in the intraoperative MR-guided focused ultrasound system is reported in the paper. The prototype RF coil was made according to the proposed decoupling method. The bench test of the prototype showed that the performance of the decoupling of the coil was excellent. The images in vivo were acquired with the designed prototype RF coil.

  7. Multi-channel multi-carrier generation using multi-wavelength frequency shifting recirculating loop.

    PubMed

    Li, Xinying; Yu, Jianjun; Dong, Ze; Zhang, Junwen; Shao, Yufeng; Chi, Nan

    2012-09-24

    We propose and experimentally demonstrate a novel scheme to generate optical frequency-locked multi-channel multi-carriers (MCMC), using a recirculating frequency shifter (RFS) loop based on multi-wavelength frequency shifting single side band (MWFS-SSB) modulation. In this scheme, optical subcarriers with multiple wavelengths can be generated each round. Furthermore, the generated MCMC are frequency- and phase-locked within each channel, and therefore can be effectively used for WDM superchannel. Dual-wavelength frequency shifting SSB modulation is carried out with dual-wavelength optical seed source in our experimental demonstration. Using this scheme, we successfully generate dual-channel multi-carriers, and one channel has 28 subcarriers while the other has 29 ones with 25-GHz subcarrier spacing. We also experimentally demonstrate that this kind of source can be used to carry 50-Gb/s optical polarization-division-multiplexing quadrature phase shift keying (PDM-QPSK) signal.

  8. Palm print image recovery and de-noising via multi-channel wavelet filter bank.

    PubMed

    Qiao, Y-H; Li, F-Q; Qiao, A-K; Zhang, J-H; Liang, K; Zeng, Y-J

    2006-01-01

    In this paper, a 3-channel wavelet transform method is introduced to recover palm print images following serious deformation. The deformation processing is actually a kind of digital re-sampling. A filter bank consisting of three filters is implemented for wavelet decomposition of the palm print image, and then a procedure of binary interpolation is performed after the image is reconstructed by another filter bank consisting of another three filters. The design of multi-channel wavelet filter bank is based on the Quadrature Mirror Filter (QMF) method. Because the noise is caused by the Morie stripe, the images are further de-noised after the geometry deformation is addressed. Acceptable results have been obtained.

  9. Reduction of group delay ripple of multi-channel chirped fiber gratings using adiabatic UV correction

    NASA Astrophysics Data System (ADS)

    Reyes, P. I.; Sumetsky, M.; Litchinitser, N. M.; Westbrook, P. S.

    2004-06-01

    We demonstrate reduction of group delay ripple (GDR) from 24 ps to 9 ps peak to peak in a four channel 43 Gb/s dispersion compensating chirped fiber grating by adiabatic UV post processing. The eye opening penalty due to the grating GDR was improved from ~2dB to <1dB for all of the channels over a range of carrier frequencies of 15GHz. Our results demonstrate that at 43 Gb/s, the adiabatic UV correction technique is sufficient to substantially improve multi-channel fiber grating performance. We also discuss three limitations of the correction technique which cause GDR to vary from channel to channel: Noise in the sampling function, cladding mode loss, and varying channel reflectivity. While these limitations are visible in our results they do not reduce the effectiveness of the adiabatic correction for our gratings.

  10. Multi-channel far-infrared HL-2A interferometer-polarimetera)

    NASA Astrophysics Data System (ADS)

    Zhou, Y.; Deng, Z. C.; Li, Y. G.; Yi, J.

    2012-10-01

    An HL-2A interferometer is upgraded to a multi-channel interferometer/polarimeter, which includes four chords for the interferometer and four chords for the polarimeter. The far-infrared lasers (at λ = 432.5 μm and 30 mW power) are used to probe plasmas horizontally in the midplane of HL-2A. A conventional heterodyne technique is used for the interferometer. Two counter-rotating circularly polarized waves are used to measure the Faraday rotation effect. A fast-phase comparator with temporal resolution of 1 μs and phase resolution 0.1° is developed. Further, the distortion of the polarization caused by the beam-splitters and the other optical components is also investigated.

  11. Multi-channel far-infrared HL-2A interferometer-polarimeter.

    PubMed

    Zhou, Y; Deng, Z C; Li, Y G; Yi, J

    2012-10-01

    An HL-2A interferometer is upgraded to a multi-channel interferometer∕polarimeter, which includes four chords for the interferometer and four chords for the polarimeter. The far-infrared lasers (at λ = 432.5 μm and 30 mW power) are used to probe plasmas horizontally in the midplane of HL-2A. A conventional heterodyne technique is used for the interferometer. Two counter-rotating circularly polarized waves are used to measure the Faraday rotation effect. A fast-phase comparator with temporal resolution of 1 μs and phase resolution 0.1° is developed. Further, the distortion of the polarization caused by the beam-splitters and the other optical components is also investigated.

  12. MS lesion segmentation using a multi-channel patch-based approach with spatial consistency

    NASA Astrophysics Data System (ADS)

    Mechrez, Roey; Goldberger, Jacob; Greenspan, Hayit

    2015-03-01

    This paper presents an automatic method for segmentation of Multiple Sclerosis (MS) in Magnetic Resonance Images (MRI) of the brain. The approach is based on similarities between multi-channel patches (T1, T2 and FLAIR). An MS lesion patch database is built using training images for which the label maps are known. For each patch in the testing image, k similar patches are retrieved from the database. The matching labels for these k patches are then combined to produce an initial segmentation map for the test case. Finally a novel iterative patch-based label refinement process based on the initial segmentation map is performed to ensure spatial consistency of the detected lesions. A leave-one-out evaluation is done for each testing image in the MS lesion segmentation challenge of MICCAI 2008. Results are shown to compete with the state-of-the-art methods on the MICCAI 2008 challenge.

  13. Field experiments of multi-channel oceanographic fluorescence lidar for oil spill and chlorophyll- a detection

    NASA Astrophysics Data System (ADS)

    Li, Xiaolong; Zhao, Chaofang; Ma, Youjun; Liu, Zhishen

    2014-08-01

    A Multi-channel Oceanographic Fluorescence Lidar (MOFL), with a UV excitation at 355 nm and multiple receiving channels at typical wavelengths of fluorescence from oil spills and chlorophyll- a (Chl- a), has been developed using the Laser-induced Fluorescence (LIF) technique. The sketch of the MOFL system equipped with a compact multi-channel photomultiplier tube (MPMT) is introduced in the paper. The methods of differentiating the oil fluorescence from the background water fluorescence and evaluating the Chl- a concentration are described. Two field experiments were carried out to investigate the field performance of the system, i.e., an experiment in coastal areas for oil pollution detection and an experiment over the Yellow Sea for Chl- a monitoring. In the coastal experiment, several oil samples and other fluorescence substances were used to analyze the fluorescence spectral characteristics for oil identification, and to estimate the thickness of oil films at the water surface. The experiment shows that both the spectral shape of fluorescence induced from surface water and the intensity ratio of two channels ( I 495/ I 405) are essential to determine oil-spill occurrence. In the airborne experiment, MOFL was applied to measure relative Chl- a concentrations in the upper layer of the ocean. A comparison of relative Chl- a concentration measurements by MOFL and the Moderate Resolution Imaging Spectroradiometer (MODIS) indicates that the two datasets are in good agreement. The results show that the MOFL system is capable of monitoring oil spills and Chl- a in the upper layer of ocean water.

  14. Scale-free brain quartet: artistic filtering of multi-channel brainwave music.

    PubMed

    Wu, Dan; Li, Chaoyi; Yao, Dezhong

    2013-01-01

    To listen to the brain activities as a piece of music, we proposed the scale-free brainwave music (SFBM) technology, which translated scalp EEGs into music notes according to the power law of both EEG and music. In the present study, the methodology was extended for deriving a quartet from multi-channel EEGs with artistic beat and tonality filtering. EEG data from multiple electrodes were first translated into MIDI sequences by SFBM, respectively. Then, these sequences were processed by a beat filter which adjusted the duration of notes in terms of the characteristic frequency. And the sequences were further filtered from atonal to tonal according to a key defined by the analysis of the original music pieces. Resting EEGs with eyes closed and open of 40 subjects were utilized for music generation. The results revealed that the scale-free exponents of the music before and after filtering were different: the filtered music showed larger variety between the eyes-closed (EC) and eyes-open (EO) conditions, and the pitch scale exponents of the filtered music were closer to 1 and thus it was more approximate to the classical music. Furthermore, the tempo of the filtered music with eyes closed was significantly slower than that with eyes open. With the original materials obtained from multi-channel EEGs, and a little creative filtering following the composition process of a potential artist, the resulted brainwave quartet opened a new window to look into the brain in an audible musical way. In fact, as the artistic beat and tonal filters were derived from the brainwaves, the filtered music maintained the essential properties of the brain activities in a more musical style. It might harmonically distinguish the different states of the brain activities, and therefore it provided a method to analyze EEGs from a relaxed audio perspective.

  15. Scale-Free Brain Quartet: Artistic Filtering of Multi-Channel Brainwave Music

    PubMed Central

    Wu, Dan; Li, Chaoyi; Yao, Dezhong

    2013-01-01

    To listen to the brain activities as a piece of music, we proposed the scale-free brainwave music (SFBM) technology, which translated scalp EEGs into music notes according to the power law of both EEG and music. In the present study, the methodology was extended for deriving a quartet from multi-channel EEGs with artistic beat and tonality filtering. EEG data from multiple electrodes were first translated into MIDI sequences by SFBM, respectively. Then, these sequences were processed by a beat filter which adjusted the duration of notes in terms of the characteristic frequency. And the sequences were further filtered from atonal to tonal according to a key defined by the analysis of the original music pieces. Resting EEGs with eyes closed and open of 40 subjects were utilized for music generation. The results revealed that the scale-free exponents of the music before and after filtering were different: the filtered music showed larger variety between the eyes-closed (EC) and eyes-open (EO) conditions, and the pitch scale exponents of the filtered music were closer to 1 and thus it was more approximate to the classical music. Furthermore, the tempo of the filtered music with eyes closed was significantly slower than that with eyes open. With the original materials obtained from multi-channel EEGs, and a little creative filtering following the composition process of a potential artist, the resulted brainwave quartet opened a new window to look into the brain in an audible musical way. In fact, as the artistic beat and tonal filters were derived from the brainwaves, the filtered music maintained the essential properties of the brain activities in a more musical style. It might harmonically distinguish the different states of the brain activities, and therefore it provided a method to analyze EEGs from a relaxed audio perspective. PMID:23717527

  16. Simulation of the High Performance Time to Digital Converter for the ATLAS Muon Spectrometer trigger upgrade

    NASA Astrophysics Data System (ADS)

    Meng, X. T.; Levin, D. S.; Chapman, J. W.; Zhou, B.

    2016-09-01

    The ATLAS Muon Spectrometer endcap thin-Resistive Plate Chamber trigger project compliments the New Small Wheel endcap Phase-1 upgrade for higher luminosity LHC operation. These new trigger chambers, located in a high rate region of ATLAS, will improve overall trigger acceptance and reduce the fake muon trigger incidence. These chambers must generate a low level muon trigger to be delivered to a remote high level processor within a stringent latency requirement of 43 bunch crossings (1075 ns). To help meet this requirement the High Performance Time to Digital Converter (HPTDC), a multi-channel ASIC designed by CERN Microelectronics group, has been proposed for the digitization of the fast front end detector signals. This paper investigates the HPTDC performance in the context of the overall muon trigger latency, employing detailed behavioral Verilog simulations in which the latency in triggerless mode is measured for a range of configurations and under realistic hit rate conditions. The simulation results show that various HPTDC operational configurations, including leading edge and pair measurement modes can provide high efficiency (>98%) to capture and digitize hits within a time interval satisfying the Phase-1 latency tolerance.

  17. High resolution time interval meter

    DOEpatents

    Martin, A.D.

    1986-05-09

    Method and apparatus are provided for measuring the time interval between two events to a higher resolution than reliability available from conventional circuits and component. An internal clock pulse is provided at a frequency compatible with conventional component operating frequencies for reliable operation. Lumped constant delay circuits are provided for generating outputs at delay intervals corresponding to the desired high resolution. An initiation START pulse is input to generate first high resolution data. A termination STOP pulse is input to generate second high resolution data. Internal counters count at the low frequency internal clock pulse rate between the START and STOP pulses. The first and second high resolution data are logically combined to directly provide high resolution data to one counter and correct the count in the low resolution counter to obtain a high resolution time interval measurement.

  18. Real-time broadband terahertz spectroscopic imaging by using a high-sensitivity terahertz camera

    NASA Astrophysics Data System (ADS)

    Kanda, Natsuki; Konishi, Kuniaki; Nemoto, Natsuki; Midorikawa, Katsumi; Kuwata-Gonokami, Makoto

    2017-02-01

    Terahertz (THz) imaging has a strong potential for applications because many molecules have fingerprint spectra in this frequency region. Spectroscopic imaging in the THz region is a promising technique to fully exploit this characteristic. However, the performance of conventional techniques is restricted by the requirement of multidimensional scanning, which implies an image data acquisition time of several minutes. In this study, we propose and demonstrate a novel broadband THz spectroscopic imaging method that enables real-time image acquisition using a high-sensitivity THz camera. By exploiting the two-dimensionality of the detector, a broadband multi-channel spectrometer near 1 THz was constructed with a reflection type diffraction grating and a high-power THz source. To demonstrate the advantages of the developed technique, we performed molecule-specific imaging and high-speed acquisition of two-dimensional (2D) images. Two different sugar molecules (lactose and D-fructose) were identified with fingerprint spectra, and their distributions in one-dimensional space were obtained at a fast video rate (15 frames per second). Combined with the one-dimensional (1D) mechanical scanning of the sample, two-dimensional molecule-specific images can be obtained only in a few seconds. Our method can be applied in various important fields such as security and biomedicine.

  19. Real-time broadband terahertz spectroscopic imaging by using a high-sensitivity terahertz camera

    PubMed Central

    Kanda, Natsuki; Konishi, Kuniaki; Nemoto, Natsuki; Midorikawa, Katsumi; Kuwata-Gonokami, Makoto

    2017-01-01

    Terahertz (THz) imaging has a strong potential for applications because many molecules have fingerprint spectra in this frequency region. Spectroscopic imaging in the THz region is a promising technique to fully exploit this characteristic. However, the performance of conventional techniques is restricted by the requirement of multidimensional scanning, which implies an image data acquisition time of several minutes. In this study, we propose and demonstrate a novel broadband THz spectroscopic imaging method that enables real-time image acquisition using a high-sensitivity THz camera. By exploiting the two-dimensionality of the detector, a broadband multi-channel spectrometer near 1 THz was constructed with a reflection type diffraction grating and a high-power THz source. To demonstrate the advantages of the developed technique, we performed molecule-specific imaging and high-speed acquisition of two-dimensional (2D) images. Two different sugar molecules (lactose and D-fructose) were identified with fingerprint spectra, and their distributions in one-dimensional space were obtained at a fast video rate (15 frames per second). Combined with the one-dimensional (1D) mechanical scanning of the sample, two-dimensional molecule-specific images can be obtained only in a few seconds. Our method can be applied in various important fields such as security and biomedicine. PMID:28198395

  20. Task Dependent Prefrontal Dysfunction in Persons with Asperger's Disorder Investigated with Multi-Channel Near-Infrared Spectroscopy

    ERIC Educational Resources Information Center

    Iwanami, Akira; Okajima, Yuka; Ota, Haruhisa; Tani, Masayuki; Yamada, Takashi; Hashimoro, Ryuichiro; Kanai, Chieko; Watanabe, Hiromi; Yamasue, Hidenori; Kawakubo, Yuki; Kato, Nobumasa

    2011-01-01

    Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder…

  1. Task Dependent Prefrontal Dysfunction in Persons with Asperger's Disorder Investigated with Multi-Channel Near-Infrared Spectroscopy

    ERIC Educational Resources Information Center

    Iwanami, Akira; Okajima, Yuka; Ota, Haruhisa; Tani, Masayuki; Yamada, Takashi; Hashimoro, Ryuichiro; Kanai, Chieko; Watanabe, Hiromi; Yamasue, Hidenori; Kawakubo, Yuki; Kato, Nobumasa

    2011-01-01

    Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder…

  2. Multi-channel non-return-to-zero format to return-to-zero format conversion with duplicate output

    NASA Astrophysics Data System (ADS)

    Yu, Yu; Zhang, Xinliang; Huang, Dexiu

    2010-12-01

    We demonstrate multi-channel regenerative non-return-to-zero (NRZ) to return-to-zero (RZ) conversions with tunable output pulse-width and single-to-dual function, using a phase modulator and an array waveguide grating (AWG). Transmission and bit error ratio (BER) show a good performance for the converted RZ signal compared with conventional one.

  3. A Novel Erbium-Doped Fiber Amplifier Simulator for Gain Excursion Estimation in Multi-Channel Dynamic Optical Network

    NASA Astrophysics Data System (ADS)

    Roy, Sharbani; Priye, Vishnu

    2012-01-01

    A novel erbium-doped fiber amplifier simulator designed using the SIMULINK toolbox of MATLAB 7.0 (The MathWorks, Natick, MA, USA) is reported in this article. The present simulator has an ability to incorporate multi-channel amplification simultaneously in both the C- and L-bands. It is realized by defining new FUNCTION block sets and replacing the MATLAB FUNCTION block set reported earlier for multi-channel amplification. Spectral variation of gain for an erbium-doped fiber amplifier simulator is first verified in both the C- and L-bands. Next, the simulator is employed to study gain excursion in a multi-channel dynamic optical network, where the change in the gain excursion by varying the pump power has also been estimated. The present approach to estimate the gain excursion will find applications in quantifying inter-channel cross-talk due to cross-gain saturation among co-propagating multi-channels in a dynamic optical network.

  4. [Characteristics of single event-related cerebral hemodynamics during verbal task in emotionally charged state measured by multi-channel near-infrared spectroscopy (NIRS) in patients with schizophrenia: comparison with healthy subjects].

    PubMed

    Shoji, Yoshihisa; Morita, Kiichiro; Mori, Keiichiro; Yamamoto, Hiroko; Fujiki, Ryo; Ishii, Youhei; Uchimura, Naohisa

    2013-01-01

    Neared infrared spectroscopy (NIRS) is one of the recently developed methodologies which can measure cerebral blood volumes to determine the blood hemoglobin (Hb) concentration simultaneously at multiple points with marked time resolution. Monitoring the changes in the Hb concentration yields site-specific readings on blood flow and, thus, on neural activities. The aim of this study was to examine the characteristics of a single event-related oxyhemoglobin concentration [oxy-Hb] changes in patients with schizophrenia using multi-channel NIRS during a word generation task, Japanese 'Shiritori', and single-word generation task in an emotionally charged state induced by three facial expressions of "crying", "neutral", and "smiling" babies' photographs. Thirty-four patients with schizophrenia and 34 age-matched healthy controls participated in the present study after giving consent. In healthy controls, [oxy-Hb] changes when viewing the "crying" baby's photograph were significantly larger than when viewing the "smiling" baby's photograph. On the other hand, in patients with schizophrenia, [oxy-Hb] changes when viewing the "smiling" baby's photograph were significantly larger than when viewing the "crying" baby's photograph. These results suggest that cautions/execution functions in patients with schizophrenia during the single event word "Shiritori" task measured by multi-channel NIRS were impaired. It was also suggested that, in patients with schizophrenia, the affective reaction influenced by each photograph may be different from healthy controls (mismatch). Multi-channel NIRS can be a useful tool for research and clinical purposes in psychiatry.

  5. The 2D method for determining the temperatures field of the gas flow at the outlet of a multi-channel heat exchanger

    NASA Astrophysics Data System (ADS)

    Slesareva, E. Yu; Elistratov, S. L.; Ovchinnikov, V. V.

    2016-10-01

    The method for experimental determination of energy efficiency in the multichannel heat exchanger was tested. The visualization of a temperatures field has been performed to determine the thermal structure of gas flows with the use of fast-response fine- meshed wire. Thermograms of the temperature fields of the multi-channels assembly at the outlet were registered by thermal imaging camera. Results show that the 2D method provides a sufficient time resolution for the temperature field for the steady-state gas flow regime, heat generation, and nonsteady regime. The 2D method allows us to determine the gas stream parameters at the channel outlet in real time, which are necessary for determining the efficiency of the heat exchanger. Qualitative and quantitative characters of temperature changes in the thermograms are consistent with modern physical understanding of the gas flow in channels.

  6. Multi-DSP and FPGA based Multi-channel Direct IF/RF Digital receiver for atmospheric radar

    NASA Astrophysics Data System (ADS)

    Yasodha, Polisetti; Jayaraman, Achuthan; Kamaraj, Pandian; Durga rao, Meka; Thriveni, A.

    2016-07-01

    Modern phased array radars depend highly on digital signal processing (DSP) to extract the echo signal information and to accomplish reliability along with programmability and flexibility. The advent of ASIC technology has made various digital signal processing steps to be realized in one DSP chip, which can be programmed as per the application and can handle high data rates, to be used in the radar receiver to process the received signal. Further, recent days field programmable gate array (FPGA) chips, which can be re-programmed, also present an opportunity to utilize them to process the radar signal. A multi-channel direct IF/RF digital receiver (MCDRx) is developed at NARL, taking the advantage of high speed ADCs and high performance DSP chips/FPGAs, to be used for atmospheric radars working in HF/VHF bands. Multiple channels facilitate the radar t be operated in multi-receiver modes and also to obtain the wind vector with improved time resolution, without switching the antenna beam. MCDRx has six channels, implemented on a custom built digital board, which is realized using six numbers of ADCs for simultaneous processing of the six input signals, Xilinx vertex5 FPGA and Spartan6 FPGA, and two ADSPTS201 DSP chips, each of which performs one phase of processing. MCDRx unit interfaces with the data storage/display computer via two gigabit ethernet (GbE) links. One of the six channels is used for Doppler beam swinging (DBS) mode and the other five channels are used for multi-receiver mode operations, dedicatedly. Each channel has (i) ADC block, to digitize RF/IF signal, (ii) DDC block for digital down conversion of the digitized signal, (iii) decoding block to decode the phase coded signal, and (iv) coherent integration block for integrating the data preserving phase intact. ADC block consists of Analog devices make AD9467 16-bit ADCs, to digitize the input signal at 80 MSPS. The output of ADC is centered around (80 MHz - input frequency). The digitized data is fed

  7. Biphasic DC measurement approach for enhanced measurement stability and multi-channel sampling of self-sensing multi-functional structural materials doped with carbon-based additives

    NASA Astrophysics Data System (ADS)

    Downey, Austin; D'Alessandro, Antonella; Ubertini, Filippo; Laflamme, Simon; Geiger, Randall

    2017-06-01

    Investigation of multi-functional carbon-based self-sensing structural materials for structural health monitoring applications is a topic of growing interest. These materials are self-sensing in the sense that they can provide measurable electrical outputs corresponding to physical changes such as strain or induced damage. Nevertheless, the development of an appropriate measurement technique for such materials is yet to be achieved, as many results in the literature suggest that these materials exhibit a drift in their output when measured with direct current (DC) methods. In most of the cases, the electrical output is a resistance and the reported drift is an increase in resistance from the time the measurement starts due to material polarization. Alternating current methods seem more appropriate at eliminating the time drift. However, published results show they are not immune to drift. Moreover, the use of multiple impedance measurement devices (LCR meters) does not allow for the simultaneous multi-channel sampling of multi-sectioned self-sensing materials due to signal crosstalk. The capability to simultaneously monitor multiple sections of self-sensing structural materials is needed to deploy these multi-functional materials for structural health monitoring. Here, a biphasic DC measurement approach with a periodic measure/discharge cycle in the form of a square wave sensing current is used to provide consistent, stable resistance measurements for self-sensing structural materials. DC measurements are made during the measurement region of the square wave while material depolarization is obtained during the discharge region of the periodic signal. The proposed technique is experimentally shown to remove the signal drift in a carbon-based self-sensing cementitious material while providing simultaneous multi-channel measurements of a multi-sectioned self-sensing material. The application of the proposed electrical measurement technique appears promising for real-time

  8. Fast and accurate multi-channel B1+ mapping based on the TIAMO technique for 7T UHF body MRI.

    PubMed

    Brunheim, Sascha; Gratz, Marcel; Johst, Sören; Bitz, Andreas Karsten; Fiedler, Thomas M; Ladd, Mark Edward; Quick, Harald Hartmut; Orzada, Stephan

    2017-10-09

    Current methods for mitigation of transmit field B1+ inhomogeneities at ultrahigh field (UHF) MRI by multi-channel radiofrequency (RF) shimming rely on accurate B1+ mapping. This can be time consuming when many RF channels have to be mapped for in vivo body MRI, where the B1 maps should ideally be acquired within a single breath-hold. Therefore, a new B1+ mapping technique (B1TIAMO) is proposed. The performance of this technique is validated against an established method (DREAM) in phantom measurements for a cylindrical head phantom with an 8-channel transmit/receive (Tx/Rx) array. Furthermore, measurements for a 32-channel Tx/Rx remote array are conducted in a large body phantom and the |B1+| map reliability is validated against simulations of the transmit RF field distribution. Finally, in vivo results of this new mapping technique for human abdomen are presented. For the head phantom (8-channel Tx/Rx coil), the single |B1+| comparison between B1 TIAMO, the direct DREAM measurements, and simulation data showed good agreement with 10-19% difference. For the large body phantom (32-channel Tx/Rx coil), B1TIAMO matched the RF field simulations well. The results demonstrate the potential to acquire 32 accurate single-channel B1+ maps for large field-of-view body imaging within only a single breath-hold of 16 s at 7T UHF MRI. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  9. Fusion of detected multi-channel maternal electrocardiogram (ECG) R-wave peak locations.

    PubMed

    Yu, Qiong; Guan, Qun; Li, Ping; Liu, Tie-Bing; Huang, Xiao-Lin; Zhao, Ying; Liu, Hong-Xing; Wang, Yuan-Qing

    2016-01-08

    Almost all promising non-invasive foetal ECG extraction methods involve accurately determining maternal ECG R-wave peaks. However, it is not easy to robustly detect accurate R-wave peaks of the maternal ECG component in an acquired abdominal ECG since it often has a low signal-to-noise ratio (SNR), sometimes containing a large foetal ECG component or other noises and interferences. This paper discusses, under the condition of acquiring multi-channel abdominal ECG signals, how to improve the robustness of maternal ECG R-wave peak detection. On the basis of summarising the current single channel ECG R-wave peak detection methods, the paper proposed a specific fusion algorithm of detected multi-channel maternal ECG R-wave peak locations. The proposed entire algorithm was then tested using two databases; one database, created by us, was composed of 343 groups of 8-channel data collected from 78 pregnant women, and the other one, called the challenge database, was from the Physionet/Computing in Cardiology Challenge 2013, including 175 groups of 4-channel data. When using these databases, each group of data was classified into two parts, called the training part and the validation test part respectively; the training part was the first 8.192 s of each group of data and the validation test part was the next 8.192 s. To show the results, three evaluation parameters-sensitivity (Se), positive predictive value (PPV) and F1-are used. The validation test results for the database we collected are Se = 99.93 %, PPV = 99.98 %, and F1 = 99.95 %, while the results for the challenge database are Se = 99.91 %, PPV = 99.86 %, and F1 = 99.88 %. The results of the test show that the robustness of our proposed whole fusion algorithm was superior to that of other outstanding algorithms for maternal R-wave detection, and is much better than that of single channel maternal R-wave detection algorithms.

  10. Sex differences in variances of multi-channel surface electromyography distribution of the vastus lateralis muscle during isometric knee extension in young adults.

    PubMed

    Nishikawa, Yuichi; Watanabe, Kohei; Takahashi, Tetsuya; Hosomi, Naohisa; Orita, Naoya; Mikami, Yukio; Maruyama, Hirofumi; Kimura, Hiroaki; Matsumoto, Masayasu

    2017-03-01

    The aim of the present study was to compare spatial electromyographic potential distribution during force production between healthy young female and male using multi-channel surface electromyography (multi-SEMG). Thirty healthy subjects (15 females) performed sustained isometric knee extension at 10% maximal voluntary contraction (MVC) task for 120 s. Multi-SEMG signals from the vastus lateralis muscle were detected and the modified entropy, coefficient of variation (CV), and correlation coefficient determined. The modified entropy and CV showed significant interaction and difference between females and males at all time points during the 10% MVC task. The correlation coefficient in females was significantly lower at 90 and 120 s than that of males. The multi-SEMG potential distribution pattern in females showed more varied motor unit recruitment during sustained low-intensity isometric contraction than that of males. Variations in motor unit recruitment may result from recruitment and/or de-recruitment of motor units.

  11. Dosimetric comparison of interstitial brachytherapy with multi-channel vaginal cylinder plans in patients with vaginal tumors.

    PubMed

    Mendez, Lucas C; Paudel, Moti; Wronski, Matt; Ravi, Ananth; Barbera, Lisa; Leung, Eric

    2017-05-18

    To evaluate the dosimetric performance of multi-channel vaginal cylinder (MCVC) against interstitial brachytherapy (ISBT) for the treatment of vaginal tumors. Vaginal tumors with extension of > 0.5 cm and ≤ 2 cm from the lateral vaginal wall and/or ≤ 1 cm in height above the vaginal vault were retrospectively selected from a ISBT registry trial database. The selected patients were treated with ISBT and targets included the intermediate (IRCTV) or high-risk (HRCTV) clinical target volumes. For technique comparison, a 35 mm MCVC was registered with the interstitial intra-vaginal cylinder. Bladder and rectum contours were transferred from the ISBT to the MCVC-BT plans. Vaginal mucosa was achieved by 3 mm uniform expansion from cylinder surface. Both the ISBT and MCVC-BT plans were optimized using the Inverse Planning Simulated Annealing optimization algorithm. After normalizing target D90 to 700 cGy, dose to organs at risk were measured and compared between ISBT and MCVC plans. Six interstitial patient plans met the inclusion criteria for this study. Four patients had vaginal primaries and two recurrent cancers in the vagina. Lower doses to bladder and rectum were seen with ISBT plans. In half of the MCVC plans, the rectal dose met the recommended constraints. For plans in which the rectal constraint was not met, the target volumes were abutting the rectum and had a cranial-caudal length ≥ 5 cm. Dose to vaginal mucosa was lower in ISBT plans directed to the HRCTVs, although no difference was seen in circumferential IRCTVs. Overall, ISBT results in decreased dose to OARs as compared to MCVC. However, MCVC BT results in acceptable doses to OARs with possible improvement in vaginal doses for circumferential targets. Careful consideration to tumor geometry and location may help guide optimal techniques in vaginal tumor brachytherapy.

  12. An Improved Cloud Classification Algorithm for China’s FY-2C Multi-Channel Images Using Artificial Neural Network

    PubMed Central

    Liu, Yu; Xia, Jun; Shi, Chun-Xiang; Hong, Yang

    2009-01-01

    The crowning objective of this research was to identify a better cloud classification method to upgrade the current window-based clustering algorithm used operationally for China’s first operational geostationary meteorological satellite FengYun-2C (FY-2C) data. First, the capabilities of six widely-used Artificial Neural Network (ANN) methods are analyzed, together with the comparison of two other methods: Principal Component Analysis (PCA) and a Support Vector Machine (SVM), using 2864 cloud samples manually collected by meteorologists in June, July, and August in 2007 from three FY-2C channel (IR1, 10.3–11.3 μm; IR2, 11.5–12.5 μm and WV 6.3–7.6 μm) imagery. The result shows that: (1) ANN approaches, in general, outperformed the PCA and the SVM given sufficient training samples and (2) among the six ANN networks, higher cloud classification accuracy was obtained with the Self-Organizing Map (SOM) and Probabilistic Neural Network (PNN). Second, to compare the ANN methods to the present FY-2C operational algorithm, this study implemented SOM, one of the best ANN network identified from this study, as an automated cloud classification system for the FY-2C multi-channel data. It shows that SOM method has improved the results greatly not only in pixel-level accuracy but also in cloud patch-level classification by more accurately identifying cloud types such as cumulonimbus, cirrus and clouds in high latitude. Findings of this study suggest that the ANN-based classifiers, in particular the SOM, can be potentially used as an improved Automated Cloud Classification Algorithm to upgrade the current window-based clustering method for the FY-2C operational products. PMID:22346714

  13. An Improved Cloud Classification Algorithm for China's FY-2C Multi-Channel Images Using Artificial Neural Network.

    PubMed

    Liu, Yu; Xia, Jun; Shi, Chun-Xiang; Hong, Yang

    2009-01-01

    The crowning objective of this research was to identify a better cloud classification method to upgrade the current window-based clustering algorithm used operationally for China's first operational geostationary meteorological satellite FengYun-2C (FY-2C) data. First, the capabilities of six widely-used Artificial Neural Network (ANN) methods are analyzed, together with the comparison of two other methods: Principal Component Analysis (PCA) and a Support Vector Machine (SVM), using 2864 cloud samples manually collected by meteorologists in June, July, and August in 2007 from three FY-2C channel (IR1, 10.3-11.3 μm; IR2, 11.5-12.5 μm and WV 6.3-7.6 μm) imagery. The result shows that: (1) ANN approaches, in general, outperformed the PCA and the SVM given sufficient training samples and (2) among the six ANN networks, higher cloud classification accuracy was obtained with the Self-Organizing Map (SOM) and Probabilistic Neural Network (PNN). Second, to compare the ANN methods to the present FY-2C operational algorithm, this study implemented SOM, one of the best ANN network identified from this study, as an automated cloud classification system for the FY-2C multi-channel data. It shows that SOM method has improved the results greatly not only in pixel-level accuracy but also in cloud patch-level classification by more accurately identifying cloud types such as cumulonimbus, cirrus and clouds in high latitude. Findings of this study suggest that the ANN-based classifiers, in particular the SOM, can be potentially used as an improved Automated Cloud Classification Algorithm to upgrade the current window-based clustering method for the FY-2C operational products.

  14. A multi-channel continuous water toxicity monitoring system: its evaluation and application to water discharged from a power plant.

    PubMed

    Kim, Byoung Chan; Gu, Man Bock

    2005-10-01

    A multi-channel continuous water toxicity monitoring system was, after confirming the systems' performance, implemented to samples of water discharged from power plants to detect and classify their toxicity using several recombinant bioluminescent bacteria. Each channel of the system is composed of a series of two mini-bioreactors to enable a continuous operation, i.e., without system interruption due to highly toxic samples. A different recombinant bacterial strain was present in each channel: DPD2540 (fabA::lux CDABE), DPD2794 (recA::luxCDABE), and TV1061 (grpE::luxCDABE), which are induced by cell membrane-, DNA-, and protein-damaging agents, respectively. GC2 (lac::luxCDABE) is a constitutive strain, whose bioluminescence is reduced by an increase in cellular toxicity. Phenol and mitomycin C (MMC) were used for evaluating the system's performance to detect toxic chemicals. These samples were injected into the second mini-bioreactor according to a step or bell-curve manner. The field samples used in this study were obtained from the water discharged from two different power plants in Korea--from a nuclear power plant and a thermo-electronic power plant--and were injected into the second mini-bioreactor to initiate the toxicity test. Each channel showed specific bioluminescent (BL) response profiles due to the toxic compounds present in the water samples. Comparing the BL signals between the standard toxic chemical samples and discharged water samples, the equivalent toxicity of the field water could be estimated. Finally, it was proved that this novel continuous toxicity monitoring system can be used as an alternative tool for the quick monitoring and control of water quality, as well as aid in the setting up of a new monitoring strategy to protect the source of tap water and in the prevention of polluted water discharge.

  15. Numerical Modeling of Tidal Dynamics and Transport in the Multi-channel Estuary of the Mekong River

    NASA Astrophysics Data System (ADS)

    Vo, T. Q.; Reyns, J.; Kernkamp, H.; Roelvink, J. A.; Van der Wegen, M.

    2016-02-01

    The Mekong estuary is an area of high biodiversity in which the ecosystem has been influenced not only by natural factors but also by anthropogenic impacts (Quang et al., 2010). The former determine the water circulation such as tide propagation, river discharge and outflow plume behavior, while the latter consist of full-dyke systems in the flood zone, saline protection systems along the coast and in general much reduced mangrove forests along the river banks and coasts. These factors influence the coastal system directly and indirectly by changing the sediment dynamics. This study aims at understanding the tidal characteristics of this multi-channel estuary by simulating the water circulation and investigating impacts of tidal forcing on the flow regime. In order to achieve these objectives, a process-based approach by using Delft3D Flexible Mesh is applied to calculate the water regime in the delta. In addition, the model has been calibrated and validated through comparison of simulated and observed tidal harmonics during different discharge stages. The results show a good agreement between simulation and observation. The model will be used to understand the system-wide sediment dynamics in all the main branches of the tide-influenced Mekong delta, from Kratié in Cambodia to the East Sea shelf. An overview of the grid is given in the attached figure. The model includes a large stretch of shelf to enable studying the seasonal plume characteristics and is driven by astronomical boundary conditions at the seaward boundary and imposed discharges at Kratié; the Tonle Sap lake in Cambodia is included as it exerts a strong control on the upstream water levels. Acknowledgements: This study was funded by ONR under Grant N00014-12-1-0433 Modeling the Mekong Delta at three different scales

  16. Development of multi-channel apparatus for electron-atom Compton scattering to study the momentum distribution of atoms in a molecule

    NASA Astrophysics Data System (ADS)

    Yamazaki, Masakazu; Hosono, Masaki; Tang, Yaguo; Takahashi, Masahiko

    2017-06-01

    We have developed multi-channel apparatus for electron-atom Compton scattering to study the momentum distribution of atoms in a molecule. It combines the features of both a spherical electron energy analyzer and a large-area position sensitive detector, thereby having an ability to cover almost completely the azimuthal angle range available for quasi-elastic electron Rutherford backscattering at an angle of 135°. Details and performance of the apparatus are reported, together with experimental results measured for Xe and CH4 at an incident electron energy of 2 keV. In particular, it is shown that the instrumental sensitivity is remarkably high, which has increased the signal count rate by nearly three orders of magnitude compared to existing setups. This technical progress would be useful for advancing atomic momentum spectroscopy studies.

  17. Development of multi-channel apparatus for electron-atom Compton scattering to study the momentum distribution of atoms in a molecule.

    PubMed

    Yamazaki, Masakazu; Hosono, Masaki; Tang, Yaguo; Takahashi, Masahiko

    2017-06-01

    We have developed multi-channel apparatus for electron-atom Compton scattering to study the momentum distribution of atoms in a molecule. It combines the features of both a spherical electron energy analyzer and a large-area position sensitive detector, thereby having an ability to cover almost completely the azimuthal angle range available for quasi-elastic electron Rutherford backscattering at an angle of 135°. Details and performance of the apparatus are reported, together with experimental results measured for Xe and CH4 at an incident electron energy of 2 keV. In particular, it is shown that the instrumental sensitivity is remarkably high, which has increased the signal count rate by nearly three orders of magnitude compared to existing setups. This technical progress would be useful for advancing atomic momentum spectroscopy studies.

  18. Detection of Multiple Innervation Zones from Multi-Channel Surface EMG Recordings with Low Signal-to-Noise Ratio Using Graph-Cut Segmentation

    PubMed Central

    Farahi, Morteza; Rojas, Monica; Mañanas, Miguel Angel; Farina, Dario

    2016-01-01

    Knowledge of the location of muscle Innervation Zones (IZs) is important in many applications, e.g. for minimizing the quantity of injected botulinum toxin for the treatment of spasticity or for deciding on the type of episiotomy during child delivery. Surface EMG (sEMG) can be noninvasively recorded to assess physiological and morphological characteristics of contracting muscles. However, it is not often possible to record signals of high quality. Moreover, muscles could have multiple IZs, which should all be identified. We designed a fully-automatic algorithm based on the enhanced image Graph-Cut segmentation and morphological image processing methods to identify up to five IZs in 60-ms intervals of very-low to moderate quality sEMG signal detected with multi-channel electrodes (20 bipolar channels with Inter Electrode Distance (IED) of 5 mm). An anisotropic multilayered cylinder model was used to simulate 750 sEMG signals with signal-to-noise ratio ranging from -5 to 15 dB (using Gaussian noise) and in each 60-ms signal frame, 1 to 5 IZs were included. The micro- and macro- averaged performance indices were then reported for the proposed IZ detection algorithm. In the micro-averaging procedure, the number of True Positives, False Positives and False Negatives in each frame were summed up to generate cumulative measures. In the macro-averaging, on the other hand, precision and recall were calculated for each frame and their averages are used to determine F1-score. Overall, the micro (macro)-averaged sensitivity, precision and F1-score of the algorithm for IZ channel identification were 82.7% (87.5%), 92.9% (94.0%) and 87.5% (90.6%), respectively. For the correctly identified IZ locations, the average bias error was of 0.02±0.10 IED ratio. Also, the average absolute conduction velocity estimation error was 0.41±0.40 m/s for such frames. The sensitivity analysis including increasing IED and reducing interpolation coefficient for time samples was performed

  19. Reprocessing of multi-channel seismic-reflection data collected in the Beaufort Sea

    USGS Publications Warehouse

    Agena, W.F.; Lee, Myung W.; Hart, P.E.

    2000-01-01

    Contained on this set of two CD-ROMs are stacked and migrated multi-channel seismic-reflection data for 65 lines recorded in the Beaufort Sea by the United States Geological Survey in 1977. All data were reprocessed by the USGS using updated processing methods resulting in improved interpretability. Each of the two CD-ROMs contains the following files: 1) 65 files containing the digital seismic data in standard, SEG-Y format; 2) 1 file containing navigation data for the 65 lines in standard SEG-P1 format; 3) an ASCII text file with cross-reference information for relating the sequential trace numbers on each line to cdp numbers and shotpoint numbers; 4) 2 small scale graphic images (stacked and migrated) of a segment of line 722 in Adobe Acrobat (R) PDF format; 5) a graphic image of the location map, generated from the navigation file; 6) PlotSeis, an MS-DOS Application that allows PC users to interactively view the SEG-Y files; 7) a PlotSeis documentation file; and 8) an explanation of the processing used to create the final seismic sections (this document).

  20. Hyperbolic Positioning with Antenna Arrays and Multi-Channel Pseudolite for Indoor Localization

    PubMed Central

    Fujii, Kenjirou; Sakamoto, Yoshihiro; Wang, Wei; Arie, Hiroaki; Schmitz, Alexander; Sugano, Shigeki

    2015-01-01

    A hyperbolic positioning method with antenna arrays consisting of proximately-located antennas and a multi-channel pseudolite is proposed in order to overcome the problems of indoor positioning with conventional pseudolites (ground-based GPS transmitters). A two-dimensional positioning experiment using actual devices is conducted. The experimental result shows that the positioning accuracy varies centimeter- to meter-level according to the geometric relation between the pseudolite antennas and the receiver. It also shows that the bias error of the carrier-phase difference observables is more serious than their random error. Based on the size of the bias error of carrier-phase difference that is inverse-calculated from the experimental result, three-dimensional positioning performance is evaluated by computer simulation. In addition, in the three-dimensional positioning scenario, an initial value convergence analysis of the non-linear least squares is conducted. Its result shows that initial values that can converge to a right position exist at least under the proposed antenna setup. The simulated values and evaluation methods introduced in this work can be applied to various antenna setups; therefore, by using them, positioning performance can be predicted in advance of installing an actual system. PMID:26437405

  1. Prefrontal activation during two Japanese Stroop tasks revealed with multi-channel near-infrared spectroscopy.

    PubMed

    Watanabe, Yukina; Sumitani, Satsuki; Hosokawa, Mai; Ohmori, Tetsuro

    2015-01-01

    The Stroop task is sometimes used in psychiatric research to elicit prefrontal activity, which presumably reflects cognitive functioning. Although there are two Stroop tasks (Kana script and Kanji script) in Japan, it is unclear whether these tasks elicit the same hemoglobin changes. Moreover, it is unclear whether psychological conditions or characteristics influence hemoglobin changes in the Japanese Stroop task. The aim of this study was to clarify whether hemoglobin changes elicited by the two Japanese Stroop tasks accurately reflected cognitive functioning. Hemoglobin changes were measured with multi-channel near-infrared spectroscopy (NIRS) in 100 healthy Japanese participants performing two Japanese Stroop tasks. The Beck-Depression Inventory (BDI), State-Trait-Anxiety Inventory (STAI), and Maudsley Obsessive Compulsive Inventory (MOCI) were administered to participants to identify psychological conditions or personality characteristics. Compared with the Kanji task, the Kana task produced a greater Stroop effect and a larger increase in oxyhemoglobin (oxy-Hb) concentration. Moreover there were no significant correlations between oxy-Hb concentration and BDI, STAI-trait, STAI-state, or MOCI scores. Therefore we found that a participant's psychological conditions or characteristics did not influence the hemodynamic changes during either task. These data suggest the Kana Stroop task is more useful than the Kanji Stroop task for NIRS studies in psychiatric research.

  2. Automatic seizure detection based on the combination of newborn multi-channel EEG and HRV information

    NASA Astrophysics Data System (ADS)

    Mesbah, Mostefa; Balakrishnan, Malarvili; Colditz, Paul B.; Boashash, Boualem

    2012-12-01

    This article proposes a new method for newborn seizure detection that uses information extracted from both multi-channel electroencephalogram (EEG) and a single channel electrocardiogram (ECG). The aim of the study is to assess whether additional information extracted from ECG can improve the performance of seizure detectors based solely on EEG. Two different approaches were used to combine this extracted information. The first approach, known as feature fusion, involves combining features extracted from EEG and heart rate variability (HRV) into a single feature vector prior to feeding it to a classifier. The second approach, called classifier or decision fusion, is achieved by combining the independent decisions of the EEG and the HRV-based classifiers. Tested on recordings obtained from eight newborns with identified EEG seizures, the proposed neonatal seizure detection algorithms achieved 95.20% sensitivity and 88.60% specificity for the feature fusion case and 95.20% sensitivity and 94.30% specificity for the classifier fusion case. These results are considerably better than those involving classifiers using EEG only (80.90%, 86.50%) or HRV only (85.70%, 84.60%).

  3. A multi-channel magnetic induction tomography measurement system for human brain model imaging.

    PubMed

    Xu, Zheng; Luo, Haijun; He, Wei; He, Chuanhong; Song, Xiaodong; Zahng, Zhanglong

    2009-06-01

    This paper proposes a multi-channel magnetic induction tomography measurement system for biological conductivity imaging in a human brain model. A hemispherical glass bowl filled with a salt solution is used as the human brain model; meanwhile, agar blocks of different conductivity are placed in the solution to simulate the intracerebral hemorrhage. The excitation and detection coils are fixed co-axially, and the axial gradiometer is used as the detection coil in order to cancel the primary field. On the outer surface of the glass bowl, 15 sensor units are arrayed in two circles as measurement parts, and a single sensor unit for cancelling the phase drift is placed beside the glass bowl. The phase sensitivity of our system is 0.204 degrees /S m(-1) with the excitation frequency of 120 kHz and the phase noise is in the range of -0.03 degrees to +0.05 degrees . Only the coaxial detection coil is available for each excitation coil; therefore, 15 phase data are collected in each measurement turn. Finally, the two-dimensional images of conductivity distribution are obtained using an interpolation algorithm. The frequency-varying experiment indicates that the imaging quality becomes better as the excitation frequency is increased.

  4. Multi-Channel RF System for MRI-Guided Transurethral Ultrasound Thermal Therapy

    NASA Astrophysics Data System (ADS)

    Yak, Nicolas; Asselin, Matthew; Chopra, Rajiv; Bronskill, Michael

    2009-04-01

    MRI-guided transurethral ultrasound thermal therapy is an approach to treating localized prostate cancer which targets precise deposition of thermal energy within a confined region of the gland. This treatment requires a system incorporating a heating applicator with multiple planar ultrasound transducers and associated RF electronics to control individual elements independently in order to achieve accurate 3D treatment. We report the design, construction, and characterization of a prototype multi-channel system capable of controlling 16 independent RF signals for a 16-element heating applicator. The main components are a control computer, microcontroller, and a 16-channel signal generator with 16 amplifiers, each incorporating a low-pass filter and transmitted/reflected power detection circuit. Each channel can deliver from 0.5 to 10 W of electrical power and good linearity from 3 to 12 MHz. Harmonic RF signals near the Larmor frequency of a 1.5 T MRI were measured to be below -30 dBm and heating experiments within the 1.5 T MR system showed no significant decrease in SNR of the temperature images. The frequency and power for all 16 channels could be changed in less than 250 ms, which was sufficiently rapid for proper performance of the control algorithms. A common backplane design was chosen which enabled an inexpensive, modular approach for each channel resulting in an overall system with minimal footprint.

  5. Multi-channel biodetection via resonant microcavities coupled to a photonic crystal waveguide

    NASA Astrophysics Data System (ADS)

    Guillermain, Elisa; Fauchet, Philippe M.

    2009-02-01

    Photonic crystal (PhC) microcavities present multiple advantages for rapid, accurate, label-free, and sensitive detection. But their principle of operation (observation of a peak in transmission) makes their integration in serial arrays difficult. Here we report on multiple resonant cavities coupled to a single photonic crystal waveguide. The device configuration consists of a PhC waveguide with a defect line along which light is guided. Several resonant microcavities, created by modifying the radius of a hole adjacent to the defect line, are coupled to the waveguide. This PhC device, operating as a multi-channel sensor, maintains the advantages of the PhC microcavities and allows for serial arrays: Light is globally transmitted through the waveguide, except for the wavelengths corresponding to the resonant modes of the microcavities. The transmission spectrum shows as many dips as there are cavities. Simulations show that the sensitivity of such structures allows the detection of single particles -typically a virus. Preliminary results show the fabrication and characterization of a double-channel structure with small defects as a solvent sensor.

  6. Optimization of multi-channel neutron focusing guides for extreme sample environments

    NASA Astrophysics Data System (ADS)

    Di Julio, D. D.; Lelièvre-Berna, E.; Courtois, P.; Andersen, K. H.; Bentley, P. M.

    2014-07-01

    In this work, we present and discuss simulation results for the design of multichannel neutron focusing guides for extreme sample environments. A single focusing guide consists of any number of supermirror-coated curved outer channels surrounding a central channel. Furthermore, a guide is separated into two sections in order to allow for extension into a sample environment. The performance of a guide is evaluated through a Monte-Carlo ray tracing simulation which is further coupled to an optimization algorithm in order to find the best possible guide for a given situation. A number of population-based algorithms have been investigated for this purpose. These include particle-swarm optimization, artificial bee colony, and differential evolution. The performance of each algorithm and preliminary results of the design of a multi-channel neutron focusing guide using these methods are described. We found that a three-channel focusing guide offered the best performance, with a gain factor of 2.4 compared to no focusing guide, for the design scenario investigated in this work.

  7. Hyperbolic Positioning with Antenna Arrays and Multi-Channel Pseudolite for Indoor Localization.

    PubMed

    Fujii, Kenjirou; Sakamoto, Yoshihiro; Wang, Wei; Arie, Hiroaki; Schmitz, Alexander; Sugano, Shigeki

    2015-09-30

    A hyperbolic positioning method with antenna arrays consisting of proximately-located antennas and a multi-channel pseudolite is proposed in order to overcome the problems of indoor positioning with conventional pseudolites (ground-based GPS transmitters). A two-dimensional positioning experiment using actual devices is conducted. The experimental result shows that the positioning accuracy varies centimeter- to meter-level according to the geometric relation between the pseudolite antennas and the receiver. It also shows that the bias error of the carrier-phase difference observables is more serious than their random error. Based on the size of the bias error of carrier-phase difference that is inverse-calculated from the experimental result, three-dimensional positioning performance is evaluated by computer simulation. In addition, in the three-dimensional positioning scenario, an initial value convergence analysis of the non-linear least squares is conducted. Its result shows that initial values that can converge to a right position exist at least under the proposed antenna setup. The simulated values and evaluation methods introduced in this work can be applied to various antenna setups; therefore, by using them, positioning performance can be predicted in advance of installing an actual system.

  8. Fabrication and validation of a multi-channel type microfluidic chip for electrokinetic streaming potential devices.

    PubMed

    Chun, Myung-Suk; Shim, Min Suk; Choi, Nak Won

    2006-02-01

    To elaborate on the applicability of the electrokinetic micro power generation, we designed and fabricated the silicon-glass as well as the PDMS-glass microfluidic chips with the unique features of a multi-channel. Besides miniaturizing the device, the key advantage of our microfluidic chip utilization lies in the reduction in water flow rate. Both a distributor and a collector taking the tapered duct geometry are positioned aiming the uniform distribution of water flow into all individual channels of the chip, in which several hundreds of single microchannels are assembled in parallel. A proper methodology is developed accompanying the deep reactive ion etching as well as the anodic bonding, and optimum process conditions necessary for hard and soft micromachining are presented. It has been shown experimentally and theoretically that the silicon-based microchannel leads to increasing streaming potential and higher external current compared to those of the PDMS-based one. A proper comparison between experimental results and theoretical computations allows justification of the validity of our novel devices. It is useful to recognize that a material inducing a higher magnitude of zeta potential has an advantage for obtaining higher power density under the same external resistance.

  9. Multi-channel linear descriptors for event-related EEG collected in brain computer interface

    NASA Astrophysics Data System (ADS)

    Pei, Xiao-mei; Zheng, Chong-xun; Xu, Jin; Bin, Guang-yu; Wang, Hong-wu

    2006-03-01

    By three multi-channel linear descriptors, i.e. spatial complexity (Ω), field power (Σ) and frequency of field changes (Φ), event-related EEG data within 8-30 Hz were investigated during imagination of left or right hand movement. Studies on the event-related EEG data indicate that a two-channel version of Ω, Σ and Φ could reflect the antagonistic ERD/ERS patterns over contralateral and ipsilateral areas and also characterize different phases of the changing brain states in the event-related paradigm. Based on the selective two-channel linear descriptors, the left and right hand motor imagery tasks are classified to obtain satisfactory results, which testify the validity of the three linear descriptors Ω, Σ and Φ for characterizing event-related EEG. The preliminary results show that Ω, Σ together with Φ have good separability for left and right hand motor imagery tasks, which could be considered for classification of two classes of EEG patterns in the application of brain computer interfaces.

  10. A novel multi-channel quadrature Doppler backward scattering reflectometer on the HL-2A tokamak

    NASA Astrophysics Data System (ADS)

    Shi, Zhongbing; Zhong, Wulu; Jiang, Min; Yang, Zengchen; Zhang, Boyu; Shi, Peiwan; Chen, Wei; Wen, Jie; Chen, Chengyuan; Fu, Bingzhong; Liu, Zetian; Ding, Xuantong; Yang, Qingwei; Duan, Xuru

    2016-11-01

    A novel 16-channel fixed frequency Doppler backward scattering (DBS) reflectometer system has been developed on the HL-2A tokamak. This system is based on the filter-based feedback loop microwave source (FFLMS) technique, which has lower phase noise and lower power variation compared with present tunable frequency generation and comb frequency array generation techniques [J. C. Hillesheim et al. Rev. Sci. Instrum. 80, 083507 (2009) and W. A. Peebles et al. Rev. Sci. Instrum. 81, 10D902 (2010)]. The 16-channel DBS system is comprised of four × four-frequency microwave transmitters and direct quadrature demodulation receivers. The working frequencies are 17-24 GHz and 31-38 GHz with the frequency interval of 1 GHz. They are designed to measure the localized intermediate wave-number (k⊥ρ ˜ 1-2, k⊥ ˜ 2-9 cm-1) density fluctuations and the poloidal rotation velocity profile of turbulence. The details of the system design and laboratory tests are presented. Preliminary results of Doppler spectra measured by the multi-channel DBS reflectometer systems are obtained. The plasma rotation and turbulence distribution during supersonic molecular beam injection are analyzed.

  11. The Research of China's Civil Aviation Passenger Multi-Channel Service Technology Platform

    NASA Astrophysics Data System (ADS)

    Zhibing, Xue; Xinming, Wang

    IATA is promoting Simplifying the Business. The traditional passenger services and business process, such as ticketing, airport counters, had a great influence. The airlines have the passenger service and convenience as the next product development requirements. With civil aviation industry and their company's products construction, the authors propose a solution of passenger multi-channel service product platform. The solution is to streamline the business as the breakthrough point, around the convenience of passengers travel services to travelers as the center, using the current mainstream and the latest IT technology to establish passenger service product platform. The solution will promote DCS e-ticketing business development and service channel diversity. In this paper, the research results have been applied in the product platform construction of the authors' company. The practice shows that through traditional business with the latest IT technologies, traditional passenger services into the emerging service model, passenger service product platform has strong advantages and characteristics. Based on the platform, various types of service products is growing rapidly.

  12. Single layer, multi-channel band-gear system for rotary joint

    NASA Technical Reports Server (NTRS)

    Kong, Kin Yuen (Inventor)

    1998-01-01

    A multi-channel band-gear system for a rotary joint has a ring gear assembly with a conducting ring band in electrical contact with corresponding conducting bands of a set of intermediary planetary gears, which in turn are in electrical contact with a conducting sun band of a sun gear assembly. The ring band is formed with a plurality of conducting segments which are electrically insulated from each other and positioned angularly in a circumferential direction of the ring gear, such that separate electrical power/signal channels are formed across the rotary joint. In a preferred embodiment having continuously connected channels, the ring band has four conducting segments at 90.degree. intervals, the sun band has two conducting segments at 180.degree. intervals, and three planetary bands are in rolling electrical contact at 120.degree. intervals between the ring band segments and the sun band segments, forming two continuously connected channels in a single layer of the band-gear system. Multiple sets of ring gear, planetary gear, and sun gear assemblies may be used in a stacked configuration in a single axial layer to further increase the number of channels provided through the band-gear system.

  13. Detection of trace materials with Fourier transform infrared spectroscopy using a multi-channel detector.

    PubMed

    Chan, K L Andrew; Kazarian, Sergei G

    2006-01-01

    FTIR spectroscopy is one of the most powerful methods for material characterization. However, the sensitivity of this analytical tool is often very limited especially for materials with weak infrared absorption or when spectral bands of the targeted trace material overlap with the spectral bands of major components. Fortunately, for heterogeneous samples, there is an opportunity to improve the sensitivity of detection by using an imaging approach. This paper explores the opportunity of enhancing the sensitivity of FTIR spectroscopy to detect trace amounts of materials using the FTIR imaging approach based on a focal plane array (FPA) detector. Model sample tablets of ibuprofen in hydroxypropyl methylcellulose (HPMC) have been used to exemplify the detection limits of FTIR spectroscopy using: (a) a conventional mercury cadmium telluride (MCT) detector and (b) a FPA detector. The sensitivity level was compared and it has been found that for this particular set of samples, the lowest concentration of ibuprofen in HPMC that can be detected using attenuated total reflection (ATR) measuring mode with the single element MCT detector was 0.35 wt% while using the FPA detector, the presence of drug has been detected in a sample that contains as little as 0.075 wt% of drug. The application of using this enhanced sensitivity offered by the multi-channel detector to probe trace amounts of drug particles left on the surface of a finger after handling a small amount of the drug has also been demonstrated. These results have broad implications for forensic, biomedical and pharmaceutical research.

  14. Multi-channel poloidal correlation reflectometry on experimental advanced superconducting tokamak

    NASA Astrophysics Data System (ADS)

    Qu, H.; Zhang, T.; Han, X.; Xiang, H. M.; Wen, F.; Geng, K. N.; Wang, Y. M.; Kong, D. F.; Cai, J. Q.; Huang, C. B.; Gao, Y.; Gao, X.; Zhang, S.

    2016-11-01

    A new multi-channel poloidal correlation reflectometry is developed at Experimental Advanced Superconducting Tokamak. Eight dielectric resonator oscillators with frequencies of 12.5 GHz, 13.5 GHz, 14.5 GHz, 15 GHz, 15.5 GHz, 16 GHz, 17 GHz, and 18 GHz are used as sources. Signals from the sources are up-converted to V band using active quadruplers and then coupled together. The output waves are launched by one single antenna after passing through a 20 dB directional coupler which can provide the reference signal. Two poloidally separated antennae are installed to receive the reflected waves from plasma. The reference and reflected signals are down-converted by mixing with a quadrupled signal from a phase-locked source with a frequency of 14.2 GHz and the IF signals pass through the filter bank. The resulting signals from the mixers are detected by I/Q demodulators. The setup enables the measurement of density fluctuation at 8 (radial) × 2 (poloidal) spatial points. A coherent mode with an increasing velocity from 50 kHz to 100 kHz is observed by using the system. The mode is located in the steep gradient region of the pedestal.

  15. Multi-channel ECG data compression using compressed sensing in eigenspace.

    PubMed

    Singh, A; Sharma, L N; Dandapat, S

    2016-06-01

    In recent years, compressed sensing (CS) has emerged as a potential alternative to traditional data compression techniques for resource-constrained telemonitoring applications. In the present work, a CS framework of data reduction is proposed for multi-channel electrocardiogram (MECG) signals in eigenspace. The sparsity of dimension-reduced eigenspace MECG signals is exploited to apply CS. First, principal component analysis (PCA) is applied over the MECG data to retain diagnostically important ECG features in a few principal eigenspace signals based on maximum variance. Then, the significant eigenspace signals are randomly projected over a sparse binary sensing matrix to obtain the reduced dimension compressive measurement vectors. The compressed measurements are quantized using a uniform quantizer and encoded by a lossless Huffman encoder. The signal recovery is carried out by an orthogonal matching pursuit (OMP) algorithm. The proposed method is evaluated on the MECG signals from PTB and CSE multilead measurement library databases. The average value of percentage root mean square difference (PRD) across the PTB database is found to be 5.24% at a compression ratio (CR)=17.76 in Lead V3 of PTB database. The visual signal quality of the reconstructed MECG signals is validated through mean opinion score (MOS), found to be 6.66%, which implies very good quality signal reconstruction. Copyright © 2016 Elsevier Ltd. All rights reserved.

  16. A Wireless Multi-Channel Recording System for Freely Behaving Mice and Rats

    PubMed Central

    Holtzman, Tahl; Ruther, Patrick; Dalley, Jeffrey W.; Lopez, Alberto; Rossi, Mark A.; Barter, Joseph W.; Salas-Meza, Daniel; Herwik, Stanislav; Holzhammer, Tobias; Morizio, James; Yin, Henry H.

    2011-01-01

    To understand the neural basis of behavior, it is necessary to record brain activity in freely moving animals. Advances in implantable multi-electrode array technology have enabled researchers to record the activity of neuronal ensembles from multiple brain regions. The full potential of this approach is currently limited by reliance on cable tethers, with bundles of wires connecting the implanted electrodes to the data acquisition system while impeding the natural behavior of the animal. To overcome these limitations, here we introduce a multi-channel wireless headstage system designed for small animals such as rats and mice. A variety of single unit and local field potential signals were recorded from the dorsal striatum and substantia nigra in mice and the ventral striatum and prefrontal cortex simultaneously in rats. This wireless system could be interfaced with commercially available data acquisition systems, and the signals obtained were comparable in quality to those acquired using cable tethers. On account of its small size, light weight, and rechargeable battery, this wireless headstage system is suitable for studying the neural basis of natural behavior, eliminating the need for wires, commutators, and other limitations associated with traditional tethered recording systems. PMID:21765934

  17. Block sparsity-based joint compressed sensing recovery of multi-channel ECG signals.

    PubMed

    Singh, Anurag; Dandapat, Samarendra

    2017-04-01

    In recent years, compressed sensing (CS) has emerged as an effective alternative to conventional wavelet based data compression techniques. This is due to its simple and energy-efficient data reduction procedure, which makes it suitable for resource-constrained wireless body area network (WBAN)-enabled electrocardiogram (ECG) telemonitoring applications. Both spatial and temporal correlations exist simultaneously in multi-channel ECG (MECG) signals. Exploitation of both types of correlations is very important in CS-based ECG telemonitoring systems for better performance. However, most of the existing CS-based works exploit either of the correlations, which results in a suboptimal performance. In this work, within a CS framework, the authors propose to exploit both types of correlations simultaneously using a sparse Bayesian learning-based approach. A spatiotemporal sparse model is employed for joint compression/reconstruction of MECG signals. Discrete wavelets transform domain block sparsity of MECG signals is exploited for simultaneous reconstruction of all the channels. Performance evaluations using Physikalisch-Technische Bundesanstalt MECG diagnostic database show a significant gain in the diagnostic reconstruction quality of the MECG signals compared with the state-of-the art techniques at reduced number of measurements. Low measurement requirement may lead to significant savings in the energy-cost of the existing CS-based WBAN systems.

  18. Multi-channel poloidal correlation reflectometry on experimental advanced superconducting tokamak.

    PubMed

    Qu, H; Zhang, T; Han, X; Xiang, H M; Wen, F; Geng, K N; Wang, Y M; Kong, D F; Cai, J Q; Huang, C B; Gao, Y; Gao, X; Zhang, S

    2016-11-01

    A new multi-channel poloidal correlation reflectometry is developed at Experimental Advanced Superconducting Tokamak. Eight dielectric resonator oscillators with frequencies of 12.5 GHz, 13.5 GHz, 14.5 GHz, 15 GHz, 15.5 GHz, 16 GHz, 17 GHz, and 18 GHz are used as sources. Signals from the sources are up-converted to V band using active quadruplers and then coupled together. The output waves are launched by one single antenna after passing through a 20 dB directional coupler which can provide the reference signal. Two poloidally separated antennae are installed to receive the reflected waves from plasma. The reference and reflected signals are down-converted by mixing with a quadrupled signal from a phase-locked source with a frequency of 14.2 GHz and the IF signals pass through the filter bank. The resulting signals from the mixers are detected by I/Q demodulators. The setup enables the measurement of density fluctuation at 8 (radial) × 2 (poloidal) spatial points. A coherent mode with an increasing velocity from 50 kHz to 100 kHz is observed by using the system. The mode is located in the steep gradient region of the pedestal.

  19. A novel multi-channel quadrature Doppler backward scattering reflectometer on the HL-2A tokamak.

    PubMed

    Shi, Zhongbing; Zhong, Wulu; Jiang, Min; Yang, Zengchen; Zhang, Boyu; Shi, Peiwan; Chen, Wei; Wen, Jie; Chen, Chengyuan; Fu, Bingzhong; Liu, Zetian; Ding, Xuantong; Yang, Qingwei; Duan, Xuru

    2016-11-01

    A novel 16-channel fixed frequency Doppler backward scattering (DBS) reflectometer system has been developed on the HL-2A tokamak. This system is based on the filter-based feedback loop microwave source (FFLMS) technique, which has lower phase noise and lower power variation compared with present tunable frequency generation and comb frequency array generation techniques [J. C. Hillesheim et al. Rev. Sci. Instrum. 80, 083507 (2009) and W. A. Peebles et al. Rev. Sci. Instrum. 81, 10D902 (2010)]. The 16-channel DBS system is comprised of four × four-frequency microwave transmitters and direct quadrature demodulation receivers. The working frequencies are 17-24 GHz and 31-38 GHz with the frequency interval of 1 GHz. They are designed to measure the localized intermediate wave-number (k⊥ρ ∼ 1-2, k⊥ ∼ 2-9 cm(-1)) density fluctuations and the poloidal rotation velocity profile of turbulence. The details of the system design and laboratory tests are presented. Preliminary results of Doppler spectra measured by the multi-channel DBS reflectometer systems are obtained. The plasma rotation and turbulence distribution during supersonic molecular beam injection are analyzed.

  20. A wireless multi-channel recording system for freely behaving mice and rats.

    PubMed

    Fan, David; Rich, Dylan; Holtzman, Tahl; Ruther, Patrick; Dalley, Jeffrey W; Lopez, Alberto; Rossi, Mark A; Barter, Joseph W; Salas-Meza, Daniel; Herwik, Stanislav; Holzhammer, Tobias; Morizio, James; Yin, Henry H

    2011-01-01

    To understand the neural basis of behavior, it is necessary to record brain activity in freely moving animals. Advances in implantable multi-electrode array technology have enabled researchers to record the activity of neuronal ensembles from multiple brain regions. The full potential of this approach is currently limited by reliance on cable tethers, with bundles of wires connecting the implanted electrodes to the data acquisition system while impeding the natural behavior of the animal. To overcome these limitations, here we introduce a multi-channel wireless headstage system designed for small animals such as rats and mice. A variety of single unit and local field potential signals were recorded from the dorsal striatum and substantia nigra in mice and the ventral striatum and prefrontal cortex simultaneously in rats. This wireless system could be interfaced with commercially available data acquisition systems, and the signals obtained were comparable in quality to those acquired using cable tethers. On account of its small size, light weight, and rechargeable battery, this wireless headstage system is suitable for studying the neural basis of natural behavior, eliminating the need for wires, commutators, and other limitations associated with traditional tethered recording systems.

  1. Signal acquisition module design for multi-channel surface magnetic resonance sounding system

    NASA Astrophysics Data System (ADS)

    Lin, Tingting; Chen, Wuqiang; Du, Wenyuan; Zhao, Jing

    2015-11-01

    To obtain a precise 2D/3D image of fissure or karst water, multi-channel magnetic resonance sounding (MRS) systems using edge-to-edge or overlapping receiving coils are needed. Thus, acquiring a nano-volt signal for a small amount of the aquifer and suppressing the mutual coupling between adjacent coils are two important issues for the design of the signal acquisition module in the system. In the present study, we propose to use a passive low pass filter, consisted of a resistance (R) and capacitance (C), to inhibit the mutual coupling effects of the coils. Four low-noise operational amplifiers LT1028, OPA124, AD745, and OP27 were compared with respect to achieving the lowest system noise. As a result, 3 pieces of LT1028 were chosen and connected in parallel to serve as preamplifier, with a sensitivity of 1.4 nV/√Hz at 2 kHz. Experimental results are presented for 2D MRS groundwater investigations conducted in the suburb of Changchun, China. The inversion result is consistent with the result of drilling log, suggesting that the signal acquisition module is well developed.

  2. A Cardiac Early Warning System with Multi Channel SCG and ECG Monitoring for Mobile Health

    PubMed Central

    Sahoo, Prasan Kumar; Thakkar, Hiren Kumar; Lee, Ming-Yih

    2017-01-01

    Use of information and communication technology such as smart phone, smart watch, smart glass and portable health monitoring devices for healthcare services has made Mobile Health (mHealth) an emerging research area. Coronary Heart Disease (CHD) is considered as a leading cause of death world wide and an increasing number of people die prematurely due to CHD. Under such circumstances, there is a growing demand for a reliable cardiac monitoring system to catch the intermittent abnormalities and detect critical cardiac behaviors which lead to sudden death. Use of mobile devices to collect Electrocardiography (ECG), Seismocardiography (SCG) data and efficient analysis of those data can monitor a patient’s cardiac activities for early warning. This paper presents a novel cardiac data acquisition method and combined analysis of Electrocardiography (ECG) and multi channel Seismocardiography (SCG) data. An early warning system is implemented to monitor the cardiac activities of a person and accuracy assessment of the early warning system is conducted for the ECG data only. The assessment shows 88% accuracy and effectiveness of our proposed analysis, which implies the viability and applicability of the proposed early warning system. PMID:28353681

  3. A Cardiac Early Warning System with Multi Channel SCG and ECG Monitoring for Mobile Health.

    PubMed

    Sahoo, Prasan Kumar; Thakkar, Hiren Kumar; Lee, Ming-Yih

    2017-03-29

    Use of information and communication technology such as smart phone, smart watch, smart glass and portable health monitoring devices for healthcare services has made Mobile Health (mHealth) an emerging research area. Coronary Heart Disease (CHD) is considered as a leading cause of death world wide and an increasing number of people die prematurely due to CHD. Under such circumstances, there is a growing demand for a reliable cardiac monitoring system to catch the intermittent abnormalities and detect critical cardiac behaviors which lead to sudden death. Use of mobile devices to collect Electrocardiography (ECG), Seismocardiography (SCG) data and efficient analysis of those data can monitor a patient's cardiac activities for early warning. This paper presents a novel cardiac data acquisition method and combined analysis of Electrocardiography (ECG) and multi channel Seismocardiography (SCG) data. An early warning system is implemented to monitor the cardiac activities of a person and accuracy assessment of the early warning system is conducted for the ECG data only. The assessment shows 88% accuracy and effectiveness of our proposed analysis, which implies the viability and applicability of the proposed early warning system.

  4. High accuracy time transfer synchronization

    NASA Technical Reports Server (NTRS)

    Wheeler, Paul J.; Koppang, Paul A.; Chalmers, David; Davis, Angela; Kubik, Anthony; Powell, William M.

    1995-01-01

    In July 1994, the U.S. Naval Observatory (USNO) Time Service System Engineering Division conducted a field test to establish a baseline accuracy for two-way satellite time transfer synchronization. Three Hewlett-Packard model 5071 high performance cesium frequency standards were transported from the USNO in Washington, DC to Los Angeles, California in the USNO's mobile earth station. Two-Way Satellite Time Transfer links between the mobile earth station and the USNO were conducted each day of the trip, using the Naval Research Laboratory(NRL) designed spread spectrum modem, built by Allen Osborne Associates(AOA). A Motorola six channel GPS receiver was used to track the location and altitude of the mobile earth station and to provide coordinates for calculating Sagnac corrections for the two-way measurements, and relativistic corrections for the cesium clocks. This paper will discuss the trip, the measurement systems used and the results from the data collected. We will show the accuracy of using two-way satellite time transfer for synchronization and the performance of the three HP 5071 cesium clocks in an operational environment.

  5. High resolution time interval counter

    DOEpatents

    Condreva, K.J.

    1994-07-26

    A high resolution counter circuit measures the time interval between the occurrence of an initial and a subsequent electrical pulse to two nanoseconds resolution using an eight megahertz clock. The circuit includes a main counter for receiving electrical pulses and generating a binary word--a measure of the number of eight megahertz clock pulses occurring between the signals. A pair of first and second pulse stretchers receive the signal and generate a pair of output signals whose widths are approximately sixty-four times the time between the receipt of the signals by the respective pulse stretchers and the receipt by the respective pulse stretchers of a second subsequent clock pulse. Output signals are thereafter supplied to a pair of start and stop counters operable to generate a pair of binary output words representative of the measure of the width of the pulses to a resolution of two nanoseconds. Errors associated with the pulse stretchers are corrected by providing calibration data to both stretcher circuits, and recording start and stop counter values. Stretched initial and subsequent signals are combined with autocalibration data and supplied to an arithmetic logic unit to determine the time interval in nanoseconds between the pair of electrical pulses being measured. 3 figs.

  6. High resolution time interval counter

    DOEpatents

    Condreva, Kenneth J.

    1994-01-01

    A high resolution counter circuit measures the time interval between the occurrence of an initial and a subsequent electrical pulse to two nanoseconds resolution using an eight megahertz clock. The circuit includes a main counter for receiving electrical pulses and generating a binary word--a measure of the number of eight megahertz clock pulses occurring between the signals. A pair of first and second pulse stretchers receive the signal and generate a pair of output signals whose widths are approximately sixty-four times the time between the receipt of the signals by the respective pulse stretchers and the receipt by the respective pulse stretchers of a second subsequent clock pulse. Output signals are thereafter supplied to a pair of start and stop counters operable to generate a pair of binary output words representative of the measure of the width of the pulses to a resolution of two nanoseconds. Errors associated with the pulse stretchers are corrected by providing calibration data to both stretcher circuits, and recording start and stop counter values. Stretched initial and subsequent signals are combined with autocalibration data and supplied to an arithmetic logic unit to determine the time interval in nanoseconds between the pair of electrical pulses being measured.

  7. Effects on humans elicited by inhaling the fragrance of essential oils: sensory test, multi-channel thermometric study and forehead surface potential wave measurement on basil and peppermint.

    PubMed

    Satoh, Tomoko; Sugawara, Yoshiaki

    2003-01-01

    The effects on humans inhaling the fragrance of essential oils were examined in terms of a sensory test, a multi-channel skin thermometer study and a portable forehead surface electroencephalographic (IBVA-EEG) measurement. The essential oils examined in this study were those of basil and peppermint, because our previous sensory test had indicated an opposite effect of these essential oils when mental work was undertaken; the inhalation of basil produced a more favorable impression after work than before work, whereas peppermint produced an unfavorable impression under these circumstances. For subjects administered basil or peppermint before and after mental work using an inhalator, a series of multi-channel skin thermometer studies and IBVA-EEG measurements were conducted. Using such paired odorants, our results showed that when compared between before and after mental work assigned to subjects: (1) the inhalation of basil, in which a favorable impression was predominant on the whole in terms of the sensory evaluation spectrum, was shown to be associated upward tendency in finger-tip skin temperature; (2) whereas these situations were opposite in the case of peppermint, in which the reversed (unfavorable) feature in sensory profiling was accompanied by a decrease in the magnitude of beta waves and a decrease in the finger-tip skin temperature both based on Welch's method, even at p < 0.01, implying a decreasing propensity of the aroused state and of the arousal response. The elucidation of such sensory and physiological endpoints of paired odorants would be of primary importance for human chemoreception science, because these are only rarely recorded during the same experiments, and this paradigm is highly informative about non-verbal responses to odorants.

  8. Implementation of a galvanically isolated low-noise power supply board for multi-channel headstage preamplifiers.

    PubMed

    Tóth, Attila; Máthé, Kálmán; Petykó, Zoltán; Szabó, Imre; Czurkó, András

    2008-06-15

    Custom made multi-channel headstage preamplifiers are traditionally powered by battery. By the use of an isolated unregulated DC/DC converter integrated circuit (DCP010512B from Texas Instruments Inc., TX, USA), here we describe the implementation of a galvanically isolated low-noise power supply board for multi-channel headstage preamplifiers. The implemented galvanically isolated power supply board provides the same quality noise free recording as the battery power supply. The non-isolated part of the power supply board is powered by standard 230 V AC/6 V DC wall mount adapter or USB cable. The described galvanically isolated power supply board can replace the batteries in preamplifier power supplies without any deterioration of the quality of recordings.

  9. Distributed capillary adiabatic tissue homogeneity model in parametric multi-channel blind AIF estimation using DCE-MRI.

    PubMed

    Kratochvíla, Jiří; Jiřík, Radovan; Bartoš, Michal; Standara, Michal; Starčuk, Zenon; Taxt, Torfinn

    2016-03-01

    One of the main challenges in quantitative dynamic contrast-enhanced (DCE) MRI is estimation of the arterial input function (AIF). Usually, the signal from a single artery (ignoring contrast dispersion, partial volume effects and flow artifacts) or a population average of such signals (also ignoring variability between patients) is used. Multi-channel blind deconvolution is an alternative approach avoiding most of these problems. The AIF is estimated directly from the measured tracer concentration curves in several tissues. This contribution extends the published methods of multi-channel blind deconvolution by applying a more realistic model of the impulse residue function, the distributed capillary adiabatic tissue homogeneity model (DCATH). In addition, an alternative AIF model is used and several AIF-scaling methods are tested. The proposed method is evaluated on synthetic data with respect to the number of tissue regions and to the signal-to-noise ratio. Evaluation on clinical data (renal cell carcinoma patients before and after the beginning of the treatment) gave consistent results. An initial evaluation on clinical data indicates more reliable and less noise sensitive perfusion parameter estimates. Blind multi-channel deconvolution using the DCATH model might be a method of choice for AIF estimation in a clinical setup. © 2015 Wiley Periodicals, Inc.

  10. MuLoG, or How to Apply Gaussian Denoisers to Multi-Channel SAR Speckle Reduction?

    NASA Astrophysics Data System (ADS)

    Deledalle, Charles-Alban; Denis, Loic; Tabti, Sonia; Tupin, Florence

    2017-09-01

    Speckle reduction is a longstanding topic in synthetic aperture radar (SAR) imaging. Since most current and planned SAR imaging satellites operate in polarimetric, interferometric or tomographic modes, SAR images are multi-channel and speckle reduction techniques must jointly process all channels to recover polarimetric and interferometric information. The distinctive nature of SAR signal (complex-valued, corrupted by multiplicative fluctuations) calls for the development of specialized methods for speckle reduction. Image denoising is a very active topic in image processing with a wide variety of approaches and many denoising algorithms available, almost always designed for additive Gaussian noise suppression. This paper proposes a general scheme, called MuLoG (MUlti-channel LOgarithm with Gaussian denoising), to include such Gaussian denoisers within a multi-channel SAR speckle reduction technique. A new family of speckle reduction algorithms can thus be obtained, benefiting from the ongoing progress in Gaussian denoising, and offering several speckle reduction results often displaying method-specific artifacts that can be dismissed by comparison between results.

  11. MuLoG, or How to Apply Gaussian Denoisers to Multi-Channel SAR Speckle Reduction?

    PubMed

    Deledalle, Charles-Alban; Denis, Loic; Tabti, Sonia; Tupin, Florence

    2017-09-01

    Speckle reduction is a longstanding topic in synthetic aperture radar (SAR) imaging. Since most current and planned SAR imaging satellites operate in polarimetric, interferometric, or tomographic modes, SAR images are multi-channel and speckle reduction techniques must jointly process all channels to recover polarimetric and interferometric information. The distinctive nature of SAR signal (complex-valued, corrupted by multiplicative fluctuations) calls for the development of specialized methods for speckle reduction. Image denoising is a very active topic in image processing with a wide variety of approaches and many denoising algorithms available, almost always designed for additive Gaussian noise suppression. This paper proposes a general scheme, called MuLoG (MUlti-channel LOgarithm with Gaussian denoising), to include such Gaussian denoisers within a multi-channel SAR speckle reduction technique. A new family of speckle reduction algorithms can thus be obtained, benefiting from the ongoing progress in Gaussian denoising, and offering several speckle reduction results often displaying method-specific artifacts that can be dismissed by comparison between results.

  12. Optimization of a multi-channel parabolic guide for the material science diffractometer STRESS-SPEC at FRM II

    NASA Astrophysics Data System (ADS)

    Rebelo Kornmeier, Joana; Ostermann, Andreas; Hofmann, Michael; Gibmeier, Jens

    2014-02-01

    Neutron strain diffractometers usually use slits to define a gauge volume within engineering samples. In this study a multi-channel parabolic neutron guide was developed to be used instead of the primary slit to minimise the loss of intensity and vertical definition of the gauge volume when using slits placed far away from the measurement position in bulky components. The major advantage of a focusing guide is that the maximum flux is not at the exit of the guide as for a slit system but at the focal point relatively far away from the exit of the guide. Monte Carlo simulations were used to optimise the multi-channel parabolic guide with respect to the instrument characteristics of the diffractometer STRESS-SPEC at the FRM II neutron source. Also the simulations are in excellent agreement with experimental measurements using the optimised multi-channel parabolic guide at the neutron diffractometer. In addition the performance of the guide was compared to the standard slit setup at STRESS-SPEC using a single bead weld sample used in earlier round robin tests for residual strain measurements.

  13. A three-dimensional tomographic velocity model above Mid Atlantic magma chamber from simulated seafloor multi-channel seismic refraction experiment

    NASA Astrophysics Data System (ADS)

    Arnulf, A. F.; Harding, A. J.; Kent, G.; Singh, S. C.

    2009-12-01

    With multi-channel seismic (MCS) data recorded on the sea surface, refraction arrivals from the upper crust typically arrive as secondary arrivals after the seafloor reflection, and therefore they do not contain any information on near seafloor velocity. Here we use a Synthetic On Bottom Experiment (SOBE) method to downward continue both shots and receivers to a depth close to the seafloor, which causes refraction arrivals from the upper crust to become first arrivals that can be followed to close to zero source receiver offsets, providing information about near surface velocity. Moreover, the high density of shots and receivers in MCS-based travel-time tomography produces a multiplicity of ray paths never reached by classical travel time tomography methods based on OBS datasets, and hence providing a high-resolution velocity of the sub-surface. We have applied this new technique to the MCS data from the SISMOMAR 3D seismic reflection survey carried out in 2005 over the Lucky Strike Segment of the Mid-Atlantic Ridge. The survey area was 18.55 km by 3.8 km, with a shot spacing of 37.5 m, receiver spacing of 12.5 m and the line spacing of 100 m. It has been the first segment of the MAR to be shown to have a quasi-steady state magma chamber, and we are creating now a high resolution velocity model to investigate in detail the links between magmatism, hydrothermal circulation and faulting in this segment. First, the data was downward continued to 1.0-1.7 km below the sea surface. Then a highly efficient algorithm was used to pick ~800,000 travel times. Because of the the high density of ray paths (up to 7 million), the first arrivals of every fifth shots was picked. To control the picking consistency along a line, picks from the preceding shot was used to guide the current one. Travel time residuals, ~10 ms, and chi-squared of the final 2D model testify to excellent picking accuracy. A 3D velocity cube was then interpolated using ten equi-spaced 2D velocity models

  14. A dynamic multi-channel speech enhancement system for distributed microphones in a car environment

    NASA Astrophysics Data System (ADS)

    Matheja, Timo; Buck, Markus; Fingscheidt, Tim

    2013-12-01

    Supporting multiple active speakers in automotive hands-free or speech dialog applications is an interesting issue not least due to comfort reasons. Therefore, a multi-channel system for enhancement of speech signals captured by distributed distant microphones in a car environment is presented. Each of the potential speakers in the car has a dedicated directional microphone close to his position that captures the corresponding speech signal. The aim of the resulting overall system is twofold: On the one hand, a combination of an arbitrary pre-defined subset of speakers' signals can be performed, e.g., to create an output signal in a hands-free telephone conference call for a far-end communication partner. On the other hand, annoying cross-talk components from interfering sound sources occurring in multiple different mixed output signals are to be eliminated, motivated by the possibility of other hands-free applications being active in parallel. The system includes several signal processing stages. A dedicated signal processing block for interfering speaker cancellation attenuates the cross-talk components of undesired speech. Further signal enhancement comprises the reduction of residual cross-talk and background noise. Subsequently, a dynamic signal combination stage merges the processed single-microphone signals to obtain appropriate mixed signals at the system output that may be passed to applications such as telephony or a speech dialog system. Based on signal power ratios between the particular microphone signals, an appropriate speaker activity detection and therewith a robust control mechanism of the whole system is presented. The proposed system may be dynamically configured and has been evaluated for a car setup with four speakers sitting in the car cabin disturbed in various noise conditions.

  15. Multi-channel transport experiments at Alcator C-Mod and comparison with gyrokinetic simulationsa)

    NASA Astrophysics Data System (ADS)

    White, A. E.; Howard, N. T.; Greenwald, M.; Reinke, M. L.; Sung, C.; Baek, S.; Barnes, M.; Candy, J.; Dominguez, A.; Ernst, D.; Gao, C.; Hubbard, A. E.; Hughes, J. W.; Lin, Y.; Mikkelsen, D.; Parra, F.; Porkolab, M.; Rice, J. E.; Walk, J.; Wukitch, S. J.; Team, Alcator C-Mod

    2013-05-01

    Multi-channel transport experiments have been conducted in auxiliary heated (Ion Cyclotron Range of Frequencies) L-mode plasmas at Alcator C-Mod [Marmar and Alcator C-Mod Group, Fusion Sci. Technol. 51(3), 3261 (2007)]. These plasmas provide good diagnostic coverage for measurements of kinetic profiles, impurity transport, and turbulence (electron temperature and density fluctuations). In the experiments, a steady sawtoothing L-mode plasma with 1.2 MW of on-axis RF heating is established and density is scanned by 20%. Measured rotation profiles change from peaked to hollow in shape as density is increased, but electron density and impurity profiles remain peaked. Ion or electron heat fluxes from the two plasmas are the same. The experimental results are compared directly to nonlinear gyrokinetic theory using synthetic diagnostics and the code GYRO [Candy and Waltz, J. Comput. Phys. 186, 545 (2003)]. We find good agreement with experimental ion heat flux, impurity particle transport, and trends in the fluctuation level ratio (T˜e/Te)/(n ˜e/ne), but underprediction of electron heat flux. We find that changes in momentum transport (rotation profiles changing from peaked to hollow) do not correlate with changes in particle transport, and also do not correlate with changes in linear mode dominance, e.g., Ion Temperature Gradient versus Trapped Electron Mode. The new C-Mod results suggest that the drives for momentum transport differ from drives for heat and particle transport. The experimental results are inconsistent with present quasilinear models, and the strong sensitivity of core rotation to density remains unexplained.

  16. A new algebraic method for quantitative proton density mapping using multi-channel coil data.

    PubMed

    Cordes, Dietmar; Yang, Zhengshi; Zhuang, Xiaowei; Sreenivasan, Karthik; Mishra, Virendra; Hua, Le H

    2017-08-01

    A difficult problem in quantitative MRI is the accurate determination of the proton density, which is an important quantity in measuring brain tissue organization. Recent progress in estimating proton density in vivo has been based on using the inverse linear relationship between the longitudinal relaxation rate T1 and proton density. In this study, the same type of relationship is being used, however, in a more general framework by constructing 3D basis functions to model the receiver bias field. The novelty of this method is that the basis functions developed are suitable to cover an entire range of inverse linearities between T1 and proton density. The method is applied by parcellating the human brain into small cubes with size 30mm x 30mm x 30mm. In each cube the optimal set of basis functions is determined to model the receiver coil sensitivities using multi-channel (32 element) coil data. For validation, we use arbitrary data from a numerical phantom where the data satisfy the conventional MR signal equations. Using added noise of different magnitude and realizations, we show that the proton densities obtained have a bias close to zero and also low noise sensitivity. The obtained root-mean-square-error rate is less than 0.2% for the estimated proton density in a realistic 3D simulation. As an application, the method is used in a small cohort of MS patients, and proton density values for specific brain structures are determined. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Multi-channel transport experiments at Alcator C-Mod and comparison with gyrokinetic simulations

    SciTech Connect

    White, A. E.; Howard, N. T.; Greenwald, M.; Reinke, M. L.; Sung, C.; Baek, S.; Barnes, M.; Dominguez, A.; Ernst, D.; Gao, C.; Hubbard, A. E.; Hughes, J. W.; Lin, Y.; Parra, F.; Porkolab, M.; Rice, J. E.; Walk, J.; Wukitch, S. J.; Team, Alcator C-Mod; Candy, J.; and others

    2013-05-15

    Multi-channel transport experiments have been conducted in auxiliary heated (Ion Cyclotron Range of Frequencies) L-mode plasmas at Alcator C-Mod [Marmar and Alcator C-Mod Group, Fusion Sci. Technol. 51(3), 3261 (2007)]. These plasmas provide good diagnostic coverage for measurements of kinetic profiles, impurity transport, and turbulence (electron temperature and density fluctuations). In the experiments, a steady sawtoothing L-mode plasma with 1.2 MW of on-axis RF heating is established and density is scanned by 20%. Measured rotation profiles change from peaked to hollow in shape as density is increased, but electron density and impurity profiles remain peaked. Ion or electron heat fluxes from the two plasmas are the same. The experimental results are compared directly to nonlinear gyrokinetic theory using synthetic diagnostics and the code GYRO [Candy and Waltz, J. Comput. Phys. 186, 545 (2003)]. We find good agreement with experimental ion heat flux, impurity particle transport, and trends in the fluctuation level ratio (T(tilde sign){sub e}/T{sub e})/(ñ{sub e}/n{sub e}), but underprediction of electron heat flux. We find that changes in momentum transport (rotation profiles changing from peaked to hollow) do not correlate with changes in particle transport, and also do not correlate with changes in linear mode dominance, e.g., Ion Temperature Gradient versus Trapped Electron Mode. The new C-Mod results suggest that the drives for momentum transport differ from drives for heat and particle transport. The experimental results are inconsistent with present quasilinear models, and the strong sensitivity of core rotation to density remains unexplained.

  18. Operations Considerations in Designing a High Speed Multi Channel Data Acquisition System

    DTIC Science & Technology

    1985-06-01

    performance monitoring and evaluation system (PMES). The system, Which is similar to that of PBFA I [1], consists of approximately 300 channels of single...will be found and new system capabilities must be added; References 1. E. L. Neau and W. B. Boyer, "PBFA-II Performance Monitoring and Evaluation System

  19. Multi-Channel Validation of Nonlinear Gyrokinetic Simulations in Alcator C-Mod I-mode Plasmas

    NASA Astrophysics Data System (ADS)

    Creely, A. J.

    2016-10-01

    New multi-channel validation of nonlinear gyrokinetic simulations (GYRO) is carried out for I-mode plasmas on Alcator C-Mod, utilizing heat fluxes, profile stiffness, and density and temperature fluctuations. I-mode plasmas are characterized by high energy confinement, similar to H-mode, but with L-mode-like particle confinement, making them favorable for reactors due to natural absence of ELMs, but without impurity accumulation [Whyte NF 2010]. At C-Mod, I-mode plasmas have been obtained across a wide range of plasma currents (Ip = 0.55-1.2MA) and magnetic fields (Bt = 2.8-8.0T). I-mode is also actively studied at ASDEX Upgrade, DIII-D and other tokamaks [Hubbard NF 2016]. Open questions remain regarding core transport in I-mode compared to L and H-mode, making validation studies in I-mode of great interest. Previous work at C-Mod found that ITG/TEM-scale GYRO simulations can match both electron and ion heat fluxes within error bars in I-mode [White PoP 2015], suggesting that multi-scale, cross-scale coupling effects [Howard PoP 2016] may be less important in I-mode than in L-mode. Adding the constraint of experimental perturbative heat diffusivity, however, revealed that ITG/TEM scale simulations do not adequately capture the high profile stiffness in I-mode [Creely NF 2016]. These results motivated more comprehensive comparisons of gyrokinetic simulations with I-mode plasmas. This talk expands upon past I-mode GYRO validation work to simultaneously constrain nonlinear gyrokinetic simulations with experimental electron and ion heat fluxes, electron temperature fluctuations measured with Correlation ECE, density fluctuations measured with Phase Contrast Imaging and reflectometry, and the temperature profile stiffness measured using partial sawtooth heat pulses. This work is supported by the US DOE under Grants DE-SC0006419 and DEFC02-99ER54512-CMOD.

  20. A numerical model prediction for boiling multi channel flow rate distribution and application in 600MW supercritical variable-pressure once-through boiler with vertical tube coils

    NASA Astrophysics Data System (ADS)

    Chen, Tingkuan; Xu, Jinliang; Wu, Lucheng

    1996-04-01

    Flow rate distribution is important in a multi channel system when the flow is heated non-uniformly. This paper describes a steady state approach for obtaining the flow distribution among various tubes of complex multi channel system. Based on the present approach, a program has been developed, which is directly applied in thermal hydraulic design and investigation of 600MW supercritical variable-pressure once through boiler.

  1. Estimation of human circadian phase via a multi-channel ambulatory monitoring system and a multiple regression model.

    PubMed

    Kolodyazhniy, Vitaliy; Späti, Jakub; Frey, Sylvia; Götz, Thomas; Wirz-Justice, Anna; Kräuchi, Kurt; Cajochen, Christian; Wilhelm, Frank H

    2011-02-01

    Reliable detection of circadian phase in humans using noninvasive ambulatory measurements in real-life conditions is challenging and still an unsolved problem. The masking effects of everyday behavior and environmental input such as physical activity and light on the measured variables need to be considered critically. Here, we aimed at developing techniques for estimating circadian phase with the lowest subject burden possible, that is, without the need of constant routine (CR) laboratory conditions or without measuring the standard circadian markers, (rectal) core body temperature (CBT), and melatonin levels. In this validation study, subjects (N = 16) wore multi-channel ambulatory monitoring devices and went about their daily routine for 1 week. The devices measured a large number of physiological, behavioral, and environmental variables, including CBT, skin temperatures, cardiovascular and respiratory function, movement/posture, ambient temperature, and the spectral composition and intensity of light received at eye level. Sleep diaries were logged electronically. After the ambulatory phase, subjects underwent a 32-h CR procedure in the laboratory for measuring unmasked circadian phase based on the "midpoint" of the salivary melatonin profile. To overcome the complex masking effects of confounding variables during ambulatory measurements, multiple regression techniques were applied in combination with the cross-validation approach to subject-independent prediction of circadian phase. The most accurate estimate of circadian phase was achieved using skin temperatures, irradiance for ambient light in the blue spectral band, and motion acceleration as predictors with lags of up to 24 h. Multiple regression showed statistically significant improvement of variance of prediction error over the traditional approaches to determining circadian phase based on single predictors (motion acceleration or sleep log), although CBT was intentionally not included as the predictor

  2. A Personalized Multi-Channel FES Controller Based on Muscle Synergies to Support Gait Rehabilitation after Stroke

    PubMed Central

    Ferrante, Simona; Chia Bejarano, Noelia; Ambrosini, Emilia; Nardone, Antonio; Turcato, Anna M.; Monticone, Marco; Ferrigno, Giancarlo; Pedrocchi, Alessandra

    2016-01-01

    It has been largely suggested in neuroscience literature that to generate a vast variety of movements, the Central Nervous System (CNS) recruits a reduced set of coordinated patterns of muscle activities, defined as muscle synergies. Recent neurophysiological studies have recommended the analysis of muscle synergies to finely assess the patient's impairment, to design personalized interventions based on the specific nature of the impairment, and to evaluate the treatment outcomes. In this scope, the aim of this study was to design a personalized multi-channel functional electrical stimulation (FES) controller for gait training, integrating three novel aspects: (1) the FES strategy was based on healthy muscle synergies in order to mimic the neural solutions adopted by the CNS to generate locomotion; (2) the FES strategy was personalized according to an initial locomotion assessment of the patient and was designed to specifically activate the impaired biomechanical functions; (3) the FES strategy was mapped accurately on the altered gait kinematics providing a maximal synchronization between patient's volitional gait and stimulation patterns. The novel intervention was tested on two chronic stroke patients. They underwent a 4-week intervention consisting of 30-min sessions of FES-supported treadmill walking three times per week. The two patients were characterized by a mild gait disability (walking speed > 0.8 m/s) at baseline. However, before treatment both patients presented only three independent muscle synergies during locomotion, resembling two different gait abnormalities. After treatment, the number of extracted synergies became four and they increased their resemblance with the physiological muscle synergies, which indicated a general improvement in muscle coordination. The originally merged synergies seemed to regain their distinct role in locomotion control. The treatment benefits were more evident for one patient, who achieved a clinically important change

  3. The structural elements and tectonics of the Lake Van basin (Eastern Anatolia) from multi-channel seismic reflection profiles

    NASA Astrophysics Data System (ADS)

    Toker, Mustafa; Sengor, A. M. Celal; Demirel Schluter, Filiz; Demirbag, Emin; Cukur, Deniz; Imren, Caner; Niessen, Frank

    2017-05-01

    This study analyzed multi-channel seismic reflection data from Lake Van, Eastern Anatolia, to provide key information on the structural elements, deformational patterns and overall tectonic structure of the Lake Van basin. The seismic data reveal three subbasins (the Tatvan, northern and Ahlat subbasins) separated by structural ridges (the northern and Ahlat ridges). The Tatvan basin is a tilted wedge-block in the west, it is a relatively undeformed and flat-lying deep basin, forming a typical example of strike-slip sedimentation. Seismic sections reveal that the deeper sedimentary sections of the Tatvan basin are locally folded, gently in the south and more intensely further north, suggesting a probable gravitational ;wedge-block; instability, oblique to the northern margin. The northern subbasin, bounded by normal oblique faults, forms a basin-margin graben structure that is elongated in a northeast-southwest direction. The east-west trending Ahlat ridge forms a fault-wedged sedimentary ridge and appears to offset by reverse oblique faults forming as a push-up rhomb horst structure. The Ahlat subbasin is a fault-wedged trough fill that is elongated in the west-east direction and appears as a horst-foot graben formed by the normal oblique faults. The northeast-southwest directed northern ridge is a faulted crestal terrace of a sublacustrine basement block. Its step-like morphology, in response to the downfaulting of the Tatvan basin, as well as its backthrusted appearance, indicates the normal oblique nature of the bounding faults. The lacustrine shelf and slope show distinctive stratigraphic features; progradational deltas, submerged fluvial channels, distorted and collapsed beddings and soft sediment deformation structures, characterizing a highly unstable nature of shelf caused by strong oblique faulting and related earthquakes. The faulting caused uplift of the Çarpanak spur zone, together with the northeastern Erek delta, deformation of deltaic structures

  4. Rayleigh waves ellipticity and mode mis-identificationin multi-channel analysis of surface waves

    NASA Astrophysics Data System (ADS)

    Boaga, J.; Cassiani, G.; Strobbia, C. L.; Vignoli, G.

    2012-12-01

    The Surface Wave Method is a popular tool for geotechnical characterization since it supplies a cost effective testing procedure capable of retrieving the shear wave velocity structure of the near surface. Several acquisition and processing approaches have been developed to infer the Rayleigh wave dispersion curve which is then inverted. Typically, single component vertical and multi channel receivers are used. In most cases the inversion of the dispersion properties is carried out assuming that the experimental dispersion curve corresponds to a single mode, mostly the fundamental Rayleigh mode, unless clear evidence dictates the existence of a more complex response, e,g. in presence of low velocity layers and inversely dispersive sites. A correct identification of the modes is essential to avoid serious misinterpretation of the subsoil model. Here we consider the typical case of higher mode mis-identification known as 'osculation' ('kissing'). In general it is called 'osculation point' the point where the energy peak shifts at low frequencies from the fundamental to the first higher mode. This jump occurs, with a continuous smooth transition, around a well-define frequency where the two modes get very close to each other reaching similar Rayleigh velocity. It is known 'osculation' happens generally in presence of strong velocity contrasts, typically with a fast bedrock underlying loose sediments. The practical limitations of the acquired data affect the spectral and modal resolution, making it often impossible to identify the presence of more than one mode. In some cases, modes have a common root and cannot be separated at the osculation point. In such cases, mode misidentification can create a large overestimation of the bedrock velocity and a large error on its depth. In this work we examine the subsoil conditions that can generate this unwanted condition, and the common field acquisition procedures that can contribute to producing data having such deceptive

  5. On the capabilities of the multi-channel singular spectrum method for extracting the main periodic and non-periodic variability from weekly GRACE data

    NASA Astrophysics Data System (ADS)

    Rangelova, E.; Sideris, M. G.; Kim, J. W.

    2012-03-01

    We study the capabilities of the method of multi-channel singular spectrum analysis (MSSA) to extract periodic signals from the Gravity Recovery and Climate Experiment (GRACE) gravity field solutions. As a non-parametric method and because of the data-adaptive nature of the base functions, the MSSA allows for modelling of non-periodic variations. In addition, it can identify modulated oscillations in the presence of noise. In our study, we analyze a complete 6-year weekly time series of the GFZ-produced GRACE spherical harmonic coefficients of degree and order 30. The MSSA filtering reduces the average root-mean-square (RMS) of the mass variability over the oceans by more than 60% when all but the annual, semi-annual and long-term variations in the spherical harmonic coefficients are filtered out. While the high variance annual signal can be extracted from the GRACE data straightforwardly, the semi-annual and long-term modes identified in the low variance portion of the data eigen-spectrum are mixed. Moreover, the semi-annual variability is contaminated by the S2 tidal alias signal shown in an example for the Hudson Bay region to possibly alter the typical two-peak seasonal cycle of the water mass anomalies. Also, some long-term modes indicate that a variation exists with a 2.1-2.5 years period, possibly of a hydrology origin, which was found by previous studies in the GFZ GRACE data. On land, we analyze time series of basin averages in Amazon, Congo, Mississippi and Nelson rivers basins computed from the filtered GRACE and Global Land Data Assimilation System (GLDAS)/Noah model coefficients. The analysis is performed in two steps: (1) an approximation of the series of basin average is computed from the identified annual, semi-annual and long-term variations in the spherical harmonic coefficients and (2) to improve the approximation, the residual variability in the basin average series is analyzed by means of singular spectrum analysis. Time lags between the

  6. Multi-channel EEG-based sleep stage classification with joint collaborative representation and multiple kernel learning.

    PubMed

    Shi, Jun; Liu, Xiao; Li, Yan; Zhang, Qi; Li, Yingjie; Ying, Shihui

    2015-10-30

    Electroencephalography (EEG) based sleep staging is commonly used in clinical routine. Feature extraction and representation plays a crucial role in EEG-based automatic classification of sleep stages. Sparse representation (SR) is a state-of-the-art unsupervised feature learning method suitable for EEG feature representation. Collaborative representation (CR) is an effective data coding method used as a classifier. Here we use CR as a data representation method to learn features from the EEG signal. A joint collaboration model is established to develop a multi-view learning algorithm, and generate joint CR (JCR) codes to fuse and represent multi-channel EEG signals. A two-stage multi-view learning-based sleep staging framework is then constructed, in which JCR and joint sparse representation (JSR) algorithms first fuse and learning the feature representation from multi-channel EEG signals, respectively. Multi-view JCR and JSR features are then integrated and sleep stages recognized by a multiple kernel extreme learning machine (MK-ELM) algorithm with grid search. The proposed two-stage multi-view learning algorithm achieves superior performance for sleep staging. With a K-means clustering based dictionary, the mean classification accuracy, sensitivity and specificity are 81.10 ± 0.15%, 71.42 ± 0.66% and 94.57 ± 0.07%, respectively; while with the dictionary learned using the submodular optimization method, they are 80.29 ± 0.22%, 71.26 ± 0.78% and 94.38 ± 0.10%, respectively. The two-stage multi-view learning based sleep staging framework outperforms all other classification methods compared in this work, while JCR is superior to JSR. The proposed multi-view learning framework has the potential for sleep staging based on multi-channel or multi-modality polysomnography signals. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. First Results from the Multi-beam Bathymetry and Multi-channel Seismic Reflection Data offshore Cide-Sinop, Southern Black Sea shelf

    NASA Astrophysics Data System (ADS)

    Alp, Y. I.; Ocakoglu, N.; Kılıc, F.; Ozel, A. O.

    2016-12-01

    The morphological and seismic features offshore Cide-Sinop at the Southern Black Sea shelf area were first time investigated by multi-beam bathymetric and multi-channel seismic reflection data under the Research Project of The Scientific and Technological Research Council of Turkey (TUBİTAK-ÇAYDAG-114Y057). Multi-beam bathymetric data were collected between 2002-2008 from onboard the research vessels TCG Çubuklu and TCG Çeşme run by the Turkish Navy, Department of Navigation, Hydrography and Oceanography (TN-DNHO) with the system an Elac-Nautic 1050D. Multi-channel seismic reflection data were collected by Turkish Petroleum Corporation (TPAO) Company in 1991. Multi-beam measurements cover 2.59 km2 areas and depths change from -1 to -500 m. Elevation data were digitized from contour lines of 1/25K topo-maps of General Command of Mapping, with the contour interval of 10 m and supplementary 5 m contours in areas of low relief. Contour and shore lines, multi-beam points were interpolated into DEMs of pixel size 10 m and 5 m respectively, using Annudem algorithm. The Geographic Information System (GIS) software was used to analyse and visualize the two data sets. Seismic reflection data were processed by conventional methods under `Echos' seismic data processing software and time migrated seismic sections were produced. DEMs were combined with seismic reflection sections to understand the morphological and morphodynamic character of the study area. First results indicate that offshore Cide-Sinop is characterised by a quite smooth and large shelf plain with an approx. 25 km wide and the water depth of about -100 m. The bathymetry gently deepens from inner shelf toward shelf break at -120 m isobath. Slope angles from 0 to 1 degrees at the shelf plain, increases about to 10 degrees beyond the shelf edge. The large shelf plain is widely characterized by sand dunes with an average height of 10 meters form E-W oriented belts of 500-1000 m in width. Toward offshore

  8. Development of hard X-ray spectrometer with high time resolution on the J-TEXT tokamak

    NASA Astrophysics Data System (ADS)

    Ma, T. K.; Chen, Z. Y.; Huang, D. W.; Tong, R. H.; Yan, W.; Wang, S. Y.; Dai, A. J.; Wang, X. L.

    2017-06-01

    A hard X-ray (HXR) spectrometer has been developed to study the runaway electrons during the sawtooth activities and during the runaway current plateau phase on the J-TEXT tokamak. The spectrometer system contains four NaI scintillator detectors and a multi-channel analyzer (MCA) with 0.5 ms time resolution. The dedicated peak detection circuit embedded in the MCA provides a pulse height analysis at count rate up to 1.2 million counts per second (Mcps), which is the key to reach the high time resolution. The accuracy and reliability of the system have been verified by comparing with the hardware integrator of HXR flux. The temporal evolution of HXR flux in different energy ranges can be obtained with high time resolution by this dedicated HXR spectrometer. The response of runaway electron transport with different energy during the sawtooth activities can be studied. The energy evolution of runaway electrons during the plateau phase of runaway current can be obtained.

  9. Portable e-Tongue based on Multi-channel LAPS Array with PVC Membrane for Rapid Environment Detection

    NASA Astrophysics Data System (ADS)

    Ha, D.; Yu, H.; Hu, N.; Wu, C. X.; Zhou, J.; Kirsanov, Dmitry; Legin, Andrey; Wang, P.

    2011-09-01

    A new kind of portable e-Tongue based on multi-channel LAPS array with PVC membrane has been designed for the rapid detection of environment situation, especially the seawater. It has the great advantages of depositing membranes which are offered by Chemistry Department, Saint-Petersburg State University on the sensors artificially with convenience and efficiency. To detect various heavy metal ions (Pb2+, Cd2+, Zn2+) simultaneously, respective Polyvinyl Chloride (PVC) membrane could be prepared on the surface of the silicon-based sensor in different channel.

  10. Cortical neural excitations in rats in vivo with using a prototype of a wireless multi-channel microstimulation system.

    PubMed

    Hayashida, Yuki; Umehira, Yuichi; Takatani, Kouki; Futami, Shigetoshi; Kameda, Seiji; Kamata, Takatsugu; Khan, Arif Ullah; Takeuchi, Yoshinori; Imai, Masaharu; Yagi, Tetsuya

    2015-08-01

    Understanding neural responses to multi-site electrical stimuli would be of essential importance for developing cortical neural prostheses. In order to provide a tool for such studies in experimental animals, we recently constructed a prototype of a wireless multi-channel microstimulation system, consisting of a stimulator chip, wireless data/power transmitters and receivers, and microcomputers. The proper operations of the system in cortical neural excitations were examined in anesthetized rats in vivo, with utilizing the voltage-sensitive dye imaging technique.

  11. The effect of multi-channel wide dynamic range compression, noise reduction, and the directional microphone on horizontal localization performance in hearing aid wearers.

    PubMed

    Keidser, Gitte; Rohrseitz, Kristin; Dillon, Harvey; Hamacher, Volkmar; Carter, Lyndal; Rass, Uwe; Convery, Elizabeth

    2006-10-01

    This study examined the effect that signal processing strategies used in modern hearing aids, such as multi-channel WDRC, noise reduction, and directional microphones have on interaural difference cues and horizontal localization performance relative to linear, time-invariant amplification. Twelve participants were bilaterally fitted with BTE devices. Horizontal localization testing using a 360 degrees loudspeaker array and broadband pulsed pink noise was performed two weeks, and two months, post-fitting. The effect of noise reduction was measured with a constant noise present at 80 degrees azimuth. Data were analysed independently in the left/right and front/back dimension and showed that of the three signal processing strategies, directional microphones had the most significant effect on horizontal localization performance and over time. Specifically, a cardioid microphone could decrease front/back errors over time, whereas left/right errors increased when different microphones were fitted to left and right ears. Front/back confusions were generally prominent. Objective measurements of interaural differences on KEMAR explained significant shifts in left/right errors. In conclusion, there is scope for improving the sense of localization in hearing aid users.

  12. Latency study of the High Performance Time to Digital Converter for the ATLAS Muon Spectrometer trigger upgrade

    NASA Astrophysics Data System (ADS)

    Meng, X. T.; Levin, D. S.; Chapman, J. W.; Li, D. C.; Yao, Z. E.; Zhou, B.

    2017-02-01

    The High Performance Time to Digital Converter (HPTDC), a multi-channel ASIC designed by the CERN Microelectronics group, has been proposed for the digitization of the thin-Resistive Plate Chambers (tRPC) in the ATLAS Muon Spectrometer Phase-1 upgrade project. These chambers, to be staged for higher luminosity LHC operation, will increase trigger acceptance and reduce or eliminate the fake muon trigger rates in the barrel-endcap transition region, corresponding to pseudo-rapidity range 1<|η|<1.3. Low level trigger candidates must be flagged within a maximum latency of 1075 ns, thus imposing stringent signal processing time performance requirements on the readout system in general, and on the digitization electronics in particular. This paper investigates the HPTDC signal latency performance based on a specially designed evaluation board coupled with an external FPGA evaluation board, when operated in triggerless mode, and under hit rate conditions expected in Phase-I. This hardware based study confirms previous simulations and demonstrates that the HPTDC in triggerless operation satisfies the digitization timing requirements in both leading edge and pair modes.

  13. Multiplex multivariate recurrence network from multi-channel signals for revealing oil-water spatial flow behavior

    NASA Astrophysics Data System (ADS)

    Gao, Zhong-Ke; Dang, Wei-Dong; Yang, Yu-Xuan; Cai, Qing

    2017-03-01

    The exploration of the spatial dynamical flow behaviors of oil-water flows has attracted increasing interests on account of its challenging complexity and great significance. We first technically design a double-layer distributed-sector conductance sensor and systematically carry out oil-water flow experiments to capture the spatial flow information. Based on the well-established recurrence network theory, we develop a novel multiplex multivariate recurrence network (MMRN) to fully and comprehensively fuse our double-layer multi-channel signals. Then we derive the projection networks from the inferred MMRNs and exploit the average clustering coefficient and the spectral radius to quantitatively characterize the nonlinear recurrent behaviors related to the distinct flow patterns. We find that these two network measures are very sensitive to the change of flow states and the distributions of network measures enable to uncover the spatial dynamical flow behaviors underlying different oil-water flow patterns. Our method paves the way for efficiently analyzing multi-channel signals from multi-layer sensor measurement system.

  14. Surface EMG and muscle fatigue: multi-channel approaches to the study of myoelectric manifestations of muscle fatigue.

    PubMed

    Marco, Gazzoni; Alberto, Botter; Taian, Vieira

    2017-05-01

    In a broad view, fatigue is used to indicate a degree of weariness. On a muscular level, fatigue posits the reduced capacity of muscle fibres to produce force, even in the presence of motor neuron excitation via either spinal mechanisms or electric pulses applied externally. Prior to decreased force, when sustaining physically demanding tasks, alterations in the muscle electrical properties take place. These alterations, termed myoelectric manifestation of fatigue, can be assessed non-invasively with a pair of surface electrodes positioned appropriately on the target muscle; traditional approach. A relatively more recent approach consists of the use of multiple electrodes. This multi-channel approach provides access to a set of physiologically relevant variables on the global muscle level or on the level of single motor units, opening new fronts for the study of muscle fatigue; it allows for: (i) a more precise quantification of the propagation velocity, a physiological variable of marked interest to the study of fatigue; (ii) the assessment of regional, myoelectric manifestations of fatigue; (iii) the analysis of single motor units, with the possibility to obtain information about motor unit control and fibre membrane changes. This review provides a methodological account on the multi-channel approach for the study of myoelectric manifestation of fatigue and on the experimental conditions to which it applies, as well as examples of their current applications.

  15. Label-free voltammetric detection of MicroRNAs at multi-channel screen printed array of electrodes comparison to graphite sensors.

    PubMed

    Erdem, Arzum; Congur, Gulsah

    2014-01-01

    The multi-channel screen-printed array of electrodes (MUX-SPE16) was used in our study for the first time for electrochemical monitoring of nucleic acid hybridization related to different miRNA sequences (miRNA-16, miRNA-15a and miRNA-660, i.e, the biomarkers for Alzheimer disease). The MUX-SPE16 was also used for the first time herein for the label-free electrochemical detection of nucleic acid hybridization combined magnetic beads (MB) assay in comparison to the disposable pencil graphite electrode (PGE). Under the principle of the magnetic beads assay, the biotinylated inosine substituted DNA probe was firstly immobilized onto streptavidin coated MB, and then, the hybridization process between probe and its complementary miRNA sequence was performed at MB surface. The voltammetric transduction was performed using differential pulse voltammetry (DPV) technique in combination with the single-use graphite sensor technologies; PGE and MUX-SPE16 for miRNA detection by measuring the guanine oxidation signal without using any external indicator. The features of single-use sensor technologies, PGE and MUX-SPE16, were discussed concerning to their reproducibility, detection limit, and selectivity compared to the results in the earlier studies presenting the electrochemical miRNA detection related to different miRNA sequences.

  16. A 12-bit, 1 MS/s SAR-ADC for a CZT-based multi-channel gamma-ray imager using a new digital calibration method

    NASA Astrophysics Data System (ADS)

    Liu, W.; Wei, T.; Yang, L.; Hu, Y.

    2016-03-01

    The successive approximation register-analog to digital converter (SAR-ADC) is widely used in the CdZnTe-based gamma-ray imager because of its outstanding characteristics of low power consumption, relatively high resolution, and small die size. This study proposes a digital bit-by-bit calibration method using an input ramp signal to further improve the conversion precision and power consumption of an SAR-ADC. The proposed method is based on the sub-radix-2 redundant architecture and the perturbation technique. The proposed calibration algorithm is simpler, more stable, and faster than traditional approaches. The prototype chip of the 12-bit, 1 MS/s radiation-hardened SAR-ADC has been designed and fabricated using the TSMC 0.35 μm 2P4M CMOS process. This SAR-ADC consumes 3 mW power and occupies a core area of 856× 802μm2. The digital bit-by-bit calibration algorithm is implemented via MATLAB for testing flexibility. The effective number of bits for this digitally calibrated SAR-ADC reaches 11.77 bits. The converter exhibits high conversion precision, low power consumption, and radiation-hardened design. Therefore, this SAR-ADC is suitable for multi-channel gamma-ray imager applications.

  17. Fluorescence-based Sensing of 2,4,6-Trinitrotoluene (TNT) Using a Multi-channeled Poly(methyl methacrylate) (PMMA) Microimmunosensor

    PubMed Central

    Charles, Paul T.; Adams, Andre A.; Howell, Peter B.; Trammell, Scott A.; Deschamps, Jeffrey R.; Kusterbeck, Anne W.

    2010-01-01

    Fluorescence immunoassays employing monoclonal antibodies directed against the explosive 2,4,6-trinitrotoluene (TNT) were conducted in a multi-channel microimmunosensor. The multi-channel microimmunosensor was prepared in poly (methyl methacrylate) (PMMA) via hot embossing from a brass molding tool. The multi-channeled microfluidic device was sol-gel coated to generate a siloxane surface that provided a scaffold for antibody immobilization. AlexaFluor-cadaverine-trinitrobenzene (AlexaFluor-Cad-TNB) was used as the reporter molecule in a displacement immunoassay. The limit of detection was 1–10 ng/mL (ppb) with a linear dynamic range that covered three orders of magnitude. In addition, antibody crossreactivity was investigated using hexahydro-1,3,5-triazine (RDX), HMX, 2,4-dinitrotoluene (DNT), 4-nitrotoluene (4-NT) and 2-amino-4,6-DNT. PMID:22315573

  18. Imaging observations of nighttime mid-latitude F-region field-aligned irregularities by an MU radar ultra-multi-channel system

    NASA Astrophysics Data System (ADS)

    Saito, S.; Yamamoto, M.; Hashiguchi, H.

    2008-08-01

    Mid-latitude F-region field-aligned irregularities (FAIs) were studied by using the middle-and-upper atmosphere (MU) radar ultra-multi-channel system with the radar imaging technique. On 12 June 2006, F-region FAI echoes with a period of about one hour were observed intermittently. These echoes were found to be embedded in medium-scale traveling ionospheric disturbances (MSTIDs) observed as variations of total electron content (TEC). The echoes drifting away from (toward) the radar were observed in the depletion (enhancement) phase of the MSTID. The Doppler velocity of the echoes is consistent with the range rates in the the range-time-intensity (RTI) maps. Fine scale structures with a spatial scale of 10 km or less were found by the radar imaging analysis. Those structures with positive Doppler velocities (moving away from the radar) appeared to drift north- (up-) westward, and those with negative Doppler velocities south- (down-) eastward approximately along the wavefronts of the MSTID. FAIs with positive Doppler velocities filling TEC depletion regions were observed.

  19. A multi-channel low-power system-on-chip for single-unit recording and narrowband wireless transmission of neural signal.

    PubMed

    Bonfanti, A; Ceravolo, M; Zambra, G; Gusmeroli, R; Spinelli, A S; Lacaita, A L; Angotzi, G N; Baranauskas, G; Fadiga, L

    2010-01-01

    This paper reports a multi-channel neural recording system-on-chip (SoC) with digital data compression and wireless telemetry. The circuit consists of a 16 amplifiers, an analog time division multiplexer, an 8-bit SAR AD converter, a digital signal processor (DSP) and a wireless narrowband 400-MHz binary FSK transmitter. Even though only 16 amplifiers are present in our current die version, the whole system is designed to work with 64 channels demonstrating the feasibility of a digital processing and narrowband wireless transmission of 64 neural recording channels. A digital data compression, based on the detection of action potentials and storage of correspondent waveforms, allows the use of a 1.25-Mbit/s binary FSK wireless transmission. This moderate bit-rate and a low frequency deviation, Manchester-coded modulation are crucial for exploiting a narrowband wireless link and an efficient embeddable antenna. The chip is realized in a 0.35- εm CMOS process with a power consumption of 105 εW per channel (269 εW per channel with an extended transmission range of 4 m) and an area of 3.1 × 2.7 mm(2). The transmitted signal is captured by a digital TV tuner and demodulated by a wideband phase-locked loop (PLL), and then sent to a PC via an FPGA module. The system has been tested for electrical specifications and its functionality verified in in-vivo neural recording experiments.

  20. Pockmarks, fluid flow, and sediments outboard of the deformation front at the Cascadia Subduction Zone from analysis of multi-channel seismic and multi-beam sonar data

    NASA Astrophysics Data System (ADS)

    Gibson, J. C.; Carbotte, S. M.; Han, S.; Carton, H. D.; Canales, P.; Nedimovic, M. R.

    2013-12-01

    Evidence of active fluid flow and the nature of the sediment section near the Cascadia deformation front are explored using multi-channel (MCS) seismic and multi-beam sonar data collected in summer 2012 using the R/V Marcus G. Langseth during the Juan de Fuca Ridge to Trench Survey. The MCS data were collected along two full plate transects (the 'Oregon' and 'Washington' transects) and one trench parallel line using a 6600 cubic inch source, and an 8 km streamer with 636 channels (12.5 m spacing). The MCS data pre-stack processing sequence includes geometry definition, trace editing, F-K filter, and deconvolution. Velocity analysis is performed via semblance and constant velocity stacks in order to create a velocity model of the sediments and upper oceanic crust. The traces are then stacked, and post-stack time migrated. The sonar data were collected using the R/V Langseth's Kongsberg EM122 1°x1° multi-beam sonar with 288 beams and 432 total soundings across track. Using MB-system the sonar data are cleaned, and the bathymetry data are then gridded at 35 m, while the backscatter data are gridded at 15 m. From the high-resolution mapping data 48 pockmarks varying in diameter from 50 m - 1 km are identified within 60 km outboard of the deformation front. The surface expression of these large features in an area of heavy sedimentation is likely indicative of active fluid flow. In order to gain sub-seafloor perspective on these features the MCS data are draped below the bathymetry/backscatter grids using QPS Fledermaus. From this perspective, specific locations for detailed velocity and attribute analysis of the sediment section are chosen. Sediment velocity and attribute analysis also provide insight into apparent differences in the sediment section and décollement formation along the Oregon and Washington plate transects. While both lines intersect areas of dense pockmark concentration, the area around the Oregon transect has been shown to contain a continuous

  1. Dual instrument for Flare and CME onset observations - Double solar Coronagraph with Solar Chromospheric Detector and Coronal Multi-channel Polarimeter at Lomnicky stit Observatory

    NASA Astrophysics Data System (ADS)

    Kucera, Ales; Tomczyk, Steven; Rybak, Jan; Sewell, Scott; Gomory, Peter; Schwartz, Pavol; Ambroz, Jaroslav; Kozak, Matus

    2015-08-01

    We report on unique dual instrument developed for simultaneous measurements of velocity and magnetic fields in the solar chromosphere and corona. We describe the technical parameters and capability of the Coronal Multi-channel Polarimeter (CoMP-S) and Solar Chromospheric detector (SCD) mounted at the Double solar coronagraph at Lomnicky Stit Observatory and working simultaneously with strictly parallel pointing of both coronagraphs. The CoMP-S is 2D spectropolarimeter designed for observations of VIS and near-IR emission lines of prominences and corona with operating spectral range: 500 - 1100 nm, sequential measurement of several VIS and near-IR lines. Its field of view is 14 arcmin x 11 arcmin. It consists of 4-stage calcite Lyot filter followed by the ferro-liquid crystal polarizer and four cameras (2 visible, 2 infrared). The capability is to deliver 2D full Stokes I, Q, U, V, using registration with 2 IR cameras (line + background) and 2 VIS cameras (line + background) SCD is a single beam instrument to observe bright chromosphere. It is a combination of tunable filter and polarimeter. Spectral resolution of the SCD ranges from 0.046 nm for observations of the HeI 1083 nm line up to to 25 pm is for observation of the HeI 587.6 nm line. The birefringent filter of the SCD has high spectral resolution, as well as spatial resolution (1.7 arcseconds) and temporal resolution (10 seconds) First results are also reported and discussed.

  2. Examination of Single- and Multi-Channel GPR Bridge Deck Condition Assessment Methods with Comparison to Complementary NDE Results

    NASA Astrophysics Data System (ADS)

    Romero, Francisco A.; Manacorda, Guido; Simi, Alessandro; Gucunski, Nenad; Parvardeh, Hooman

    2013-04-01

    A sixteen-channel GPR system which houses both longitudinally- and transversely-polarized, 2.0 GHz antenna elements within a single housing was compared with a single-channel GPR system that was separately using both 1.5GHz and 2.6GHz antennas oriented in the transverse polarization, for the purpose of determining effectiveness of bridge deck condition assessment. The multi-channel system has obvious benefits which include closely-spaced GPR antennas (channels) that provide better lateral resolution, as well as combined data sets from co-linear antennas oriented in both the transverse and longitudinal polarizations, which has benefits for imaging within the deck's internal structure. However, the primary objective was to determine whether the multi-channel system would perform in a similar manner to proven single-channel GPR technology during an attenuation-based GPR condition assessment on an older, partially deteriorated deck in northwestern New Jersey that is annually exposed to freeze-thaw conditions as well as de-icing salts. These assessments were made by focusing on identifying the strongest reflections from the upper mat of transversely-oriented rebars within the deck and comparing reflection strength, or conversely, attenuation of the GPR signal, from each of the 'picked' GPR rebar responses. Coordinates for each of the GPR picks, along with amplitude or attenuation measurements, were gridded and contour-plotted for the purpose of identifying areas identified as either relatively deteriorated or sound. Initially, results were compared for data with no applied correction that takes into account GPR signal attenuation with increasing depth within the concrete deck. Final GPR maps were produced incorporating a depth-correction technique similar to what is described by Barnes, et. al., Romero, et. al, and Gucunski, et. al., a process which has been clearly demonstrated to better correlate GPR results with not only ground truth (cores, sounding) but also with

  3. Widefield TSCSPC-systems with large-area-detectors: application in simultaneous multi-channel-FLIM

    NASA Astrophysics Data System (ADS)

    Stepanov, Sergei; Bakhlanov, Sergei; Drobchenko, Evgeny; Eckert, Hann-Jörg; Kemnitz, Klaus

    2010-11-01

    Novel proximity-type Time- and Space-Correlated Single Photon Counting (TSCSPC) crossed-delay-line (DL)- and multi-anode (MA)-systems of outstanding performance and homogeneity were developed, using large-area detector heads of 25 and 40 mm diameter. Instrument response functions IRF(space) = (60 +/- 5) μm FWHM and IRF(time) = (28 +/- 3) ps FWHM were achieved over the full 12 cm2 area of the detector. Deadtime at throughput of 105 cps is 10% for "high-resolution" system and 5% in the "video"-system at 106 cps, at slightly reduced time- and space resolution. A fluorescence lifetime of (3.5 +/- 1) ps can be recovered from multi-exponential dynamics of a single living cyanobacterium (Acaryochloris marina). The present large-area detectors are particularly useful in simultaneous multichannel applications, such as 2-colour anisotropy or 4-colour lifetime imaging, utilizing dual- or quad-view image splitters. The long-term stability, low- excitation-intensity (< 100 mW/cm2) widefield systems enable minimal-invasive observation, without significant bleaching or photodynamic reactions, thus allowing long-period observation of up to several hours in living cells.

  4. MULTI-CHANNEL PULSED DOPPLER SIGNAL PROCESSING FOR VASCULAR MEASUREMENTS IN MICE

    PubMed Central

    Reddy, Anilkumar K.; Madala, Sridhar; Jones, Alan D.; Caro, Walter A.; Eberth, John F.; Pham, Thuy T.; Taffet, George E.; Hartley, Craig J.

    2009-01-01

    The small size, high heart rate, and small tissue displacement of a mouse require small sensors that are capable of high spatial and temporal tissue displacement resolutions and multichannel data acquisition systems with high sampling rates for simultaneous measurement of high fidelity signals. We developed and evaluated an ultrasound-based mouse vascular research system (MVRS) that can be used to characterize vascular physiology in normal, transgenic, surgically altered, and disease models of mice. The system consists of multiple 10/20MHz ultrasound transducers, analog electronics for Doppler displacement and velocity measurement, signal acquisition and processing electronics, and personal computer based software for real-time and offline analysis. In-vitro testing of the system showed that it is capable of measuring tissue displacement as low as 0.1 µm and tissue velocity (µm/s) starting from 0. The system can measure blood velocities up to 9 m/s (with 10 MHz Doppler at a PRF of 125 kHz) and has a temporal resolution of 0.1 milliseconds. Ex-vivo tracking of an excised mouse carotid artery wall using our Doppler technique and a video pixel tracking technique showed high correlation (R2=0.99). The system can be used to measure diameter changes, augmentation index, impedance spectra, pulse wave velocity, characteristic impedance, forward and backward waves, reflection coefficients, coronary flow reserve, and cardiac motion in murine models. The system will facilitate the study of mouse vascular mechanics and arterial abnormalities resulting in significant impact on the evaluation and screening of vascular disease in mice. PMID:19854566

  5. Design of the multi-channel electroencephalography-based brain-computer interface with novel dry sensors.

    PubMed

    Wu, Shang-Lin; Liao, Lun-De; Liou, Chang-Hong; Chen, Shi-An; Ko, Li-Wei; Chen, Bo-Wei; Wang, Po-Sheng; Chen, Sheng-Fu; Lin, Chin-Teng

    2012-01-01

    The traditional brain-computer interface (BCI) system measures the electroencephalography (EEG) signals by the wet sensors with the conductive gel and skin preparation processes. To overcome the limitations of traditional BCI system with conventional wet sensors, a wireless and wearable multi-channel EEG-based BCI system is proposed in this study, including the wireless EEG data acquisition device, dry spring-loaded sensors, a size-adjustable soft cap. The dry spring-loaded sensors are made of metal conductors, which can measure the EEG signals without skin preparation and conductive gel. In addition, the proposed system provides a size-adjustable soft cap that can be used to fit user's head properly. Indeed, the results are shown that the proposed system can properly and effectively measure the EEG signals with the developed cap and sensors, even under movement. In words, the developed wireless and wearable BCI system is able to be used in cognitive neuroscience applications.

  6. New approach to information fusion for Lipschitz classifiers ensembles: Application in multi-channel C-OTDR-monitoring systems

    SciTech Connect

    Timofeev, Andrey V.; Egorov, Dmitry V.

    2016-06-08

    This paper presents new results concerning selection of an optimal information fusion formula for an ensemble of Lipschitz classifiers. The goal of information fusion is to create an integral classificatory which could provide better generalization ability of the ensemble while achieving a practically acceptable level of effectiveness. The problem of information fusion is very relevant for data processing in multi-channel C-OTDR-monitoring systems. In this case we have to effectively classify targeted events which appear in the vicinity of the monitored object. Solution of this problem is based on usage of an ensemble of Lipschitz classifiers each of which corresponds to a respective channel. We suggest a brand new method for information fusion in case of ensemble of Lipschitz classifiers. This method is called “The Weighing of Inversely as Lipschitz Constants” (WILC). Results of WILC-method practical usage in multichannel C-OTDR monitoring systems are presented.

  7. Examination of the temporal effect in a flow injection analysis system using multi-channel absorbance detection.

    PubMed

    Lin, Shu-Hui; Chang, Kai-Chieh; Chen, Yu-Chun; Yu, Tiing; Pai, Su-Cheng

    2009-05-22

    In addition to the Poiseuille effect, a so-called temporal effect was proposed recently to elucidate the commonly observed tailing peak signals of flow injection analysis (FIA). A multi-channel absorbance detector was used in this study to obtain the FIA peaks on both the spatial and temporal coordinates. The temporal effect was analyzed by comparison of the profiles between the experimental and the corresponding Gaussian peaks, and by comparison of asymmetry factors between the spatial and the temporal peaks. The temporal effect appeared to be the major factor under flow rates ranging from 0.5 to 8 ml min (-1). This was despite the presence of a spatially frontal peak observed in the FIA tubing, which was found to result in a tailing peak on the temporal coordinate due to this discussed cause. In addition, the temporal effect became greater as the flow rate increased.

  8. ARX filtering of single-sweep movement-related brain macropotentials in mono- and multi-channel recordings.

    PubMed

    Capitanio, L; Filligoi, G C; Liberati, D; Cerutti, S; Babiloni, F; Fattorini, L; Urbano, A

    1994-03-01

    A technique of stochastic parametric identification and filtering is applied to the analysis of single-sweep event-related potentials. This procedure, called AutoRegressive with n eXogenous inputs (ARXn), models the recorded signal as the sum of n+1 signals: the background EEG activity, modeled as an autoregressive process driven by white noise, and n signals, one of which represents a filtered version of a reference signal carrying the average information contained in each sweep. The other (n-1) signals could represent various sources of noise (i.e., artifacts, EOG, etc.). An evaluation of the effects of both artifact suppression and accurate selection of the average signal on mono- or multi-channel scalp recordings is presented.

  9. New approach to information fusion for Lipschitz classifiers ensembles: Application in multi-channel C-OTDR-monitoring systems

    NASA Astrophysics Data System (ADS)

    Timofeev, Andrey V.; Egorov, Dmitry V.

    2016-06-01

    This paper presents new results concerning selection of an optimal information fusion formula for an ensemble of Lipschitz classifiers. The goal of information fusion is to create an integral classificatory which could provide better generalization ability of the ensemble while achieving a practically acceptable level of effectiveness. The problem of information fusion is very relevant for data processing in multi-channel C-OTDR-monitoring systems. In this case we have to effectively classify targeted events which appear in the vicinity of the monitored object. Solution of this problem is based on usage of an ensemble of Lipschitz classifiers each of which corresponds to a respective channel. We suggest a brand new method for information fusion in case of ensemble of Lipschitz classifiers. This method is called "The Weighing of Inversely as Lipschitz Constants" (WILC). Results of WILC-method practical usage in multichannel C-OTDR monitoring systems are presented.

  10. A multi-channel fibre-optic link for analog telemetry

    SciTech Connect

    Shubaly, M.R.; Plato, J.G.

    1983-08-01

    Control of an ion beam injector requires a reliable telemetry link for analog signals between the high voltage dome and ground. This paper describes a selfscanning, self-checking system capable of transmitting up to sixteen channels of analog data (in each direction) with eight bit resolution over a dual light link. The technique used is serial transmission of eight bit words using standard UART's (Universal Asynchronous Receiver Transmitter) which provide much of the error detection and timing. Two versions, one stand-alone for manual control, the other an input/output interface board that plugs into a control microcomputer, have been designed. For sixteen channels, the data is updated every 3.2 milliseconds. The simple design and low parts count provide a low cost analog telemetry system.

  11. Plasmonic Nanoholes in a Multi-Channel Microarray Format for Parallel Kinetic Assays and Differential Sensing

    PubMed Central

    Im, Hyungsoon; Lesuffleur, Antoine; Lindquist, Nathan C.; Oh, Sang-Hyun

    2009-01-01

    We present nanohole arrays in a gold film integrated with a 6-channel microfluidic chip for parallel measurements of molecular binding kinetics. Surface plasmon resonance effects in the nanohole arrays enable real-time label-free measurements of molecular binding events in each channel, while adjacent negative reference channels can record measurement artifacts such as bulk solution index changes, temperature variations, or changing light absorption in the liquid. Using this platform, streptavidin-biotin specific binding kinetics are measured at various concentrations with negative controls. A high-density microarray of 252 biosensing pixels is also demonstrated with a packing density of 106 sensing elements/cm2, which can potentially be coupled with a massively parallel array of microfluidic channels for protein microarray applications. PMID:19284776

  12. Chemotherapeutic (cyclophosphamide) effects on rat breast tumor hemodynamics monitored by multi-channel NIRS

    NASA Astrophysics Data System (ADS)

    Kim, Jae G.; Zhao, Dawen; Mason, Ralph P.; Liu, Hanli

    2005-04-01

    We previously suggested that the two time constants quantified from the increase of tumor oxyhemoglobin concentration, ▵ [HbO2], during hyperoxic gas intervention are associated with two blood flow/perfusion rates in well perfused and poorly perfused regions of tumors. In this study, our hypothesis is that when cancer therapy is applied to a tumor, changes in blood perfusion will occur and be detected by the NIRS. For experiments, systemic chemotherapy, cyclophosphamide (CTX), was applied to two groups of rats bearing syngeneic 13762NF mammary adenocarcinomas: one group received a single high dose i. p. (200 mg/kg CTX) and the other group continuous low doses (20 mg/kg CTX i. p. for 10 days). Time courses of changes in tumor ▵ [HbO2] were measured at four different locations on the breast tumors non-invasively with an inhaled gas sequence of air-oxygen-air before and after CTX administration. Both rat body weight and tumor volume decreased after administration of high dose CTX, but continuous low doses showed decrease of tumor volume only. Baselines (without any therapy) intra- and inter-tumor heterogeneity of vascular oxygenation during oxygen inhalation were similar to our previous observations. After CTX treatment, significant changes in vascular hemodynamic response to oxygen inhalation were observed from both groups. By fitting the increase of ▵ [HbO2] during oxygen inhalation, we have obtained changes of vascular structure ratio and also of perfusion rate ratio before and after chemotherapy. The preliminary results suggest that cyclophosphamide has greatest effect on the well perfused tumor vasculature. Overall, our study supports our earlier hypothesis, proving that the effects of chemotherapy in tumor may be monitored non-invasively by using NIRS to detect changes of hemodynamics induced with respiratory challenges.

  13. Evolutionary Algorithm Based Feature Optimization for Multi-Channel EEG Classification

    PubMed Central

    Wang, Yubo; Veluvolu, Kalyana C.

    2017-01-01

    The most BCI systems that rely on EEG signals employ Fourier based methods for time-frequency decomposition for feature extraction. The band-limited multiple Fourier linear combiner is well-suited for such band-limited signals due to its real-time applicability. Despite the improved performance of these techniques in two channel settings, its application in multiple-channel EEG is not straightforward and challenging. As more channels are available, a spatial filter will be required to eliminate the noise and preserve the required useful information. Moreover, multiple-channel EEG also adds the high dimensionality to the frequency feature space. Feature selection will be required to stabilize the performance of the classifier. In this paper, we develop a new method based on Evolutionary Algorithm (EA) to solve these two problems simultaneously. The real-valued EA encodes both the spatial filter estimates and the feature selection into its solution and optimizes it with respect to the classification error. Three Fourier based designs are tested in this paper. Our results show that the combination of Fourier based method with covariance matrix adaptation evolution strategy (CMA-ES) has the best overall performance. PMID:28203141

  14. Sub-nanosecond time resolved light emission study for diffuse discharges in air under steep high voltage pulses

    NASA Astrophysics Data System (ADS)

    Tardiveau, P.; Magne, L.; Marode, E.; Ouaras, K.; Jeanney, P.; Bournonville, B.

    2016-10-01

    Pin-to-plane discharges in centimetre air gaps and standard conditions of pressure and temperature are generated under very high positive nanosecond scale voltage pulses. The experimental study is based on recordings of sub-nanosecond time resolved and Abel-processed light emission profiles and their complete correlation to electrical current waveforms. The effects of the voltage pulse features (amplitude between 20 and 90 kV, rise time between 2 and 5.2 ns, and time rate between 4 and 40 kV · ns-1) and the electrode configuration (gap distance between 10 and 30 mm, pin radius between 10 and 200 µm, copper, molybdenum or tungsten pin material) are described. A three time period development can be found: a glow-like structure with monotonic light profiles during the first 1.5 ns whose size depends on time voltage rate, a shell-like structure with bimodal profiles whose duration and extension in space depends on rise time, and either diffuse or multi-channel regime for the connection to the cathode plane according to gap distance. The transition of the light from monotonic to bimodal patterns reveals the relative effects and dynamics of streamer space charge and external laplacian field. A classical 2D-fluid model for streamer propagation has been used and adapted for very high and steep voltage pulses. It shows the formation of a strong space charge (streamer) very close to the pin, but also a continuity of emission between the pin and the streamer, and electric fields higher than the critical ionization field (28 kV · cm-1 in air) almost in the whole gap and very early in the discharge propagation.

  15. OCTOCAM: a fast multi-channel imager and spectrograph proposed for the Gemini Observatory

    NASA Astrophysics Data System (ADS)

    de Ugarte Postigo, A.; Roming, P.; Thöne, C. C.; van der Horst, A. J.; Pope, S.; García Vargas, M. L.; Sánchez-Blanco, E.; Maldonado Medina, M.; Content, R.; Snik, F.; Killough, R.; Winters, G.; Persson, K.; Jeffers, S.; Riva, A.; Bianco, A.; Zanutta, A.

    2016-08-01

    OCTOCAM has been proposed to the Gemini Observatory as a workhorse imager and spectrograph that will fulfill the needs of a large number of research areas in the 2020s. It is based on the use of high-efficiency dichroics to divide the incoming light in eight different channels, four optical and four infrared, each optimized for its wavelength range. In its imaging mode, it will observe a field of 3'x3' simultaneously in g, r, i, z, Y, J, H, and KS bands. It will obtain long-slit spectroscopy covering the range from 3700 to 23500 Å with a resolution of 4000 and a slit length of 3 arcminutes. To avoid slit losses, the instrument it will be equipped with an atmospheric dispersion corrector for the complete spectral range. Thanks to the use of state of the art detectors, OCTOCAM will allow high time-resolution observations and will have negligible overheads in classical observing modes. It will be equipped with a unique integral field unit that will observe in the complete spectral range with an on-sky coverage of 9.7"x6.8", composed of 17 slitlets, 0.4" wide each. Finally, a state-of-the-art polarimetric unit will allow us to obtain simultaneous full Stokes spectropolarimetry of the range between 3700 and 22000 Å.

  16. High energy real-time imaging studies

    SciTech Connect

    Haskins, J.J.; Dolan, K.W.; Perkins, D.E.; Rikard, D.; Schneberk, D.J.

    1993-04-01

    Performance characteristics of high energy real-time radiography (RTR) systems were optimized by interchanging components and varying optical coupling methods. Phosphor screens, fiber optic scintillation plates, monolithic high density glass scintillation plates, mirror coatings, different cameras and integration times were studied. X-ray sources were 4- and 9-MeV linear accelerators. High density monolithic glass, high resolution and wide dynamic range CCD cameras, and special focusing and fixturing methods have provided significantly improved spatial resolution and contrast for our high energy real-rime imaging. RTR systems with improved performance characteristics and proper translational/rotational staging were adapted for computed tomography applications.

  17. Real-time, high frequency QRS electrocardiograph

    NASA Technical Reports Server (NTRS)

    Schlegel, Todd T. (Inventor); DePalma, Jude L. (Inventor); Moradi, Saeed (Inventor)

    2006-01-01

    Real time cardiac electrical data are received from a patient, manipulated to determine various useful aspects of the ECG signal, and displayed in real time in a useful form on a computer screen or monitor. The monitor displays the high frequency data from the QRS complex in units of microvolts, juxtaposed with a display of conventional ECG data in units of millivolts or microvolts. The high frequency data are analyzed for their root mean square (RMS) voltage values and the discrete RMS values and related parameters are displayed in real time. The high frequency data from the QRS complex are analyzed with imbedded algorithms to determine the presence or absence of reduced amplitude zones, referred to herein as RAZs. RAZs are displayed as go, no-go signals on the computer monitor. The RMS and related values of the high frequency components are displayed as time varying signals, and the presence or absence of RAZs may be similarly displayed over time.

  18. HAI: A novel airborne multi-channel hygrometer for fast multi-phase H2O quantification: Performance of the HAI instrument during the first flights on the German HALO aircraft

    NASA Astrophysics Data System (ADS)

    Buchholz, B.; Ebert, V.; Kraemer, M.; Afchine, A.

    2014-12-01

    Common gas phase H2O measurements on fast airborne platforms e.g. using backward facing or "Rosemount"-inlets can lead to a high risk of ice and droplets contamination. In addition, currently no single hygrometer exists that allows a simultaneous, high-speed measurement of all phases (gas, liquid, ice) with the same detection principle. In the rare occasions multi-phase measurements are realized, gas-and condensed-phase observations rely on different methods, instruments and calibration strategies so that precision and accuracy levels are quite difficult to quantify. This is effectively avoided by the novel TDLAS instrument, HAI, Hygrometer for Atmospheric Investigation, which allows a simultaneous, high speed, multi-phase detection without any sensor calibration in a unique "2+2" channel concept. Hai combines two independent wavelength channels, at 1.4 µm and at 2.6 µm, for a wide dynamic range from 1 to 30 000 ppmv, with a simultaneous closed path (extractive) and open path detection. Thus, "Total", i.e. gas-phase plus condensed-phase water is measured by sampling via a forward facing inlet into "closed-path" extractive cells. A selective, sampling-free, high speed gas phase detection is realized via a dual-wavelength "open-path" cell placed outside of the aircraft fuselage. All channels can be sampled with 120 Hz (measurement cycle time Dt=1.6 ms) allowing an unprecedented spatial resolution of 30 cm at 900 km/h. The evaluation of the individual multi-channel raw-data is done post flight, without any channel interdependencies, in calibration-free mode, thus allowing fast, accurate and precise multi-phase water detection in flight. The performance could be shown in more than 200 net flights hours in three scientific flight campaigns (TACTS, ESMVal, ML-CIRRUS) on the new German HALO aircraft. In addition the level of the accuracy of the calibration free evaluation was evaluated at the German national primary water vapor standard.

  19. Fabrication of a cyclic olefin copolymer planar waveguide embedded in a multi-channel poly(methyl methacrylate) fluidic chip for evanescence excitation.

    PubMed

    Okagbare, Paul I; Emory, Jason M; Datta, Proyag; Goettert, Jost; Soper, Steven A

    2010-01-07

    The fabrication and characterization of a novel cyclic olefin copolymer (COC) waveguide embedded in a poly(methyl methacrylate), PMMA, fluidic chip configured in a multi-channel format with an integrated monolithic prism for evanescent fluorescence excitation are reported. The fabrication approach allowed the embedded waveguide to be situated orthogonal to a series of fluidic channels within the PMMA wafer to sample fluorescent solutions in these channels using the evanescence properties of the waveguide. Construction of the device was achieved using several fabrication techniques including high precision micromilling, hot embossing and stenciling of a polymer melt to form the waveguide and coupling prism. A waveguide channel was fabricated in the fluidic chip's cover plate, also made from PMMA, and was loaded with a COC solution using a pre-cast poly(dimethylsiloxane), PDMS, stencil containing a prism-shaped recess. The PMMA substrate contained multiple channels (100 microm wide x 30 microm deep with a pitch of 100 microm) that were situated orthogonal to the waveguide to allow penetration of the evanescent field into the sampling solution. The optical properties of the waveguide in terms of its transmission properties and penetration depth of the evanescent field in the adjacent solution were evaluated. Finally, the device was used for laser-induced fluorescence evanescent excitation of a dye solution hydrodynamically flowing through multiple microfluidic channels in the chip and processed using a microscope equipped with a charge-coupled device (CCD) for parallel readout. The device and optical system were able to image 11 channels simultaneously with a limit-of-detection of 7.1 x 10(-20) mol at a signal-to-noise ratio of 2. The waveguide was simple to manufacture and could be scaled to illuminate much higher channel numbers making it appropriate for high-throughput measurements using evanescent excitation.

  20. The Development of Multi-Channel GPS Receivers at the CSIR - National Metrology Laboratory

    DTIC Science & Technology

    2000-11-01

    generation of Consultative Committee on Time and Frequency (CCTF) Sub-group on GPS and GLONASS Time Transfer Standards ( CGGTTS ) GPS data format files...and remote programmability available on the market at the time. 130 SOFTWARE The software developed had to generate data files in the CGGTTS GPS...firmware command [4]. According to the CGGTTS directives, a Common View (CV) track is 780 seconds long, and has 52 data points, to which a

  1. Calibration of the R/V Marcus G. Langseth Seismic Array in shallow Cascadia waters using the Multi-Channel Streamer

    NASA Astrophysics Data System (ADS)

    Crone, T. J.; Tolstoy, M.; Carton, H. D.

    2013-12-01

    In the summer of 2012, two multi-channel seismic (MCS) experiments, Cascadia Open-Access Seismic Transects (COAST) and Ridge2Trench, were conducted in the offshore Cascadia region. An area of growing environmental concern with active source seismic experiments is the potential impact of the received sound on marine mammals, but data relating to this issue is limited. For these surveys sound level 'mitigation radii' are established for the protection of marine mammals, based on direct arrival modeling and previous calibration experiments. Propagation of sound from seismic arrays can be accurately modeled in deep-water environments, but in shallow and sloped environments the complexity of local geology and bathymetry can make it difficult to predict sound levels as a function of distance from the source array. One potential solution to this problem is to measure the received levels in real-time using the ship's streamer (Diebold et al., 2010), which would allow the dynamic determination of suitable mitigation radii. We analyzed R/V Langseth streamer data collected on the shelf and slope off the Washington coast during the COAST experiment to measure received levels in situ up to 8 km away from the ship. Our analysis shows that water depth and bathymetric features can affect received levels in shallow water environments. The establishment of dynamic mitigation radii based on local conditions may help maximize the safety of marine mammals while also maximizing the ability of scientists to conduct seismic research. With increasing scientific and societal focus on subduction zone environments, a better understanding of shallow water sound propagation is essential for allowing seismic exploration of these hazardous environments to continue. Diebold, J. M., M. Tolstoy, L. Doermann, S. Nooner, S. Webb, and T. J. Crone (2010) R/V Marcus G. Langseth Seismic Source: Modeling and Calibration. Geochemistry, Geophysics, Geosystems, 11, Q12012, doi:10.1029/2010GC003216.

  2. Enhancement of absorption and resistance of motion utilizing a multi-channel opto-electronic sensor to effectively monitor physiological signs during sport exercise

    NASA Astrophysics Data System (ADS)

    Alzahrani, Abdullah; Hu, Sijung; Azorin-Peris, Vicente; Barrett, Laura; Esliger, Dale; Hayes, Matthew; Akbare, Shafique; Achart, Jérôme; Kuoch, Sylvain

    2015-03-01

    This study presents an effective engineering approach for human vital signs monitoring as increasingly demanded by personal healthcare. The aim of this work is to study how to capture critical physiological parameters efficiently through a well-constructed electronic system and a robust multi-channel opto-electronic patch sensor (OEPS), together with a wireless communication. A unique design comprising multi-wavelength illumination sources and a rapid response photo sensor with a 3-axis accelerometer enables to recover pulsatile features, compensate motion and increase signal-to-noise ratio. An approved protocol with designated tests was implemented at Loughborough University a UK leader in sport and exercise assessment. The results of sport physiological effects were extracted from the datasets of physical movements, i.e. sitting, standing, waking, running and cycling. t-test, Bland-Altman and correlation analysis were applied to evaluate the performance of the OEPS system against Acti-Graph and Mio-Alpha.There was no difference in heart rate measured using OEPS and both Acti-Graph and Mio-Alpha (both p<0.05). Strong correlations were observed between HR measured from the OEPS and both the Acti-graph and Mio-Alpha (r = 0.96, p<0.001). Bland-Altman analysis for the Acti-Graph and OEPS found the bias 0.85 bpm, the standard deviation 9.20 bpm, and the limits of agreement (LOA) -17.18 bpm to +18.88 bpm for lower and upper limits of agreement respectively, for the Mio-Alpha and OEPS the bias is 1.63 bpm, standard deviation SD8.62 bpm, lower and upper limits of agreement, - 15.27 bpm and +18.58 bpm respectively. The OEPS demonstrates a real time, robust and remote monitoring of cardiovascular function.

  3. Structure study of sodium disilicate glass in a Paris-Edinburgh cell using monochromatic x-ray diffraction and a multi-channel collimator

    NASA Astrophysics Data System (ADS)

    Yu, T.; Prescher, C.; Wang, Y.; Prakapenka, V.; Eng, P. J.; Kono, Y.; Stubbs, J.; Shen, G.

    2014-12-01

    The ratio of non-bridging oxygen to tetrahedrally coordinated cation (NBO/T) represents the degree of polymerization and is one well-known way of structurally categorizing amorphous silicates. A number of studies show that at ambient temperature ultrasonic sound velocities (both longitudinal and transverse) of SiO2 (Zha et al., 1994; Yokoyama et al., 2010; Kono et al., 2011) and other polymerized silicate glasses, including sodium disilicate which we recently studied (Yu et al., in prep), decrease with increasing pressure and reach minima between 2-3GPa, above which the velocities turn around and display a normal, positive pressure dependence. To systematically study the velocity profile of amorphous silicates and their relationship with the NBO/T value and detailed local structure, synthesized sodium disilicate glass was loaded into a Paris-Edinburgh (PE) cell to investigate pressure induced structure change using X-ray total scattering and pair distribution function (PDF) analysis at the GSECARS 13-ID-C beamline at the APS. X-ray diffraction data of the glass sample has been collected up to 3GPa at ambient temperature by utilizing a 60KeV monochromatic X-ray beam. We used a new multi-channel collimator (MCC; cf., Mezouar et al., 2002) to effectively remove unwanted scattering signal from the surrounding pressure media, and interfaced the Paris-Edinburgh cell (PEC) with the general-purpose diffractometer to decrease data collection time for glass structure measurement by more than one order of magnitude comparing with energy dispersive X-ray diffraction method. Results of our recent silicate glass structure measurements will be presented. We acknowledge the supports of COMPRES on facility development, of GSECARS and HPCAT for the Paris-Edinburgh press system.

  4. China's first intermediate resolution multi-channel seismic survey in the northern Victoria Land Basin and Terror Rift, Ross Sea, Antarctica

    NASA Astrophysics Data System (ADS)

    Shen, Zhongyan; Gao, Jinyao; Zhang, Tao; Wang, Wei; Ding, Weifeng; Zhang, Sheng

    2017-04-01

    The West Antarctic Rift System (WARS) represents one of the largest active continental rift systems on Earth and is less well known than other rift systems because it is largely covered by thick ice. The Terror Rift (TR), superimposing on the Victoria Land Basin (VLB) in the western Ross Sea, is identified as the most recent deformational zone of the WARS, thus will provide knowledge of the active deformation process of the WARS. The structure and kinematics of the TR is under debate. Originally, the TR was thought to consist of two parts: the Discovery Graben and the magmatically-intruded Lee Arch. New denser seismic grid in the middle and southern segments of the TR revealed a different structure of the Lee Arch while the northern segment of the TR is not well studied. The glacial history of the VLB/TR region is another attractive issue to the geologists since this area records the behavior information of EAIS and WAIS. In the southern part of the VLB, especially in the McMurdo Sound, the framework of the glacial history is well established after several deep cores which recovery the whole stratigraphic sequences since the onset of the glaciation. However, the glacial history of the northern part of the VLB/TR is less well studied and here we emphasize its importance because the northern part of the VLB/TR is a link between the well-studied southern VLB and the sediment-well-preserved Northern Basin. During the 32nd Chinese National Antarctic Research Expedition, on the board of the RV XueLong, we collected intermediate resolution multi-channel seismic reflection data in the northern VLB/TR. These data will establish new constraints on the timing of deformation, structure and kinematics of the TR, and the history of the EAIS and WAIS.

  5. Giving High School Students More Time

    ERIC Educational Resources Information Center

    Nagel, David

    2008-01-01

    A recent Web search returned more than 1.1 billion hits for the phrase "time management," a concept that school leaders hear in seminars, read about in books, and are trained in during professional development. But, like principals, students too need the advantage of a little more time. One high school in Indiana is giving students the…

  6. Precision Timing Calorimeter for High Energy Physics

    DOE PAGES

    Anderson, Dustin; Apresyan, Artur; Bornheim, Adolf; ...

    2016-04-01

    Here, we present studies on the performance and characterization of the time resolution of LYSO-based calorimeters. Results for an LYSO sampling calorimeter and an LYSO-tungsten Shashlik calorimeter are presented. We also demonstrate that a time resolution of 30 ps is achievable for the LYSO sampling calorimeter. Timing calorimetry is described as a tool for mitigating the effects due to the large number of simultaneous interactions in the high luminosity environment foreseen for the Large Hadron Collider.

  7. Assembly of a Multi-channel Video System to Simultaneously Record Cerebral Emboli with Cerebral Imaging

    PubMed Central

    Stoner-Duncan, Benjamin; Kim, Sae Jin; Mergeche, Joanna L.; Anastasian, Zirka H.; Heyer, Eric J.

    2011-01-01

    Stroke remains a significant risk of carotid revascularization for atherosclerotic disease. Emboli generated at the time of treatment either using endarterectomy or stent-angioplasty may progress with blood flow and lodge in brain arteries. Recently, the use of protection devices to trap emboli created at the time of revascularization has helped to establish a role for stent-supported angioplasty compared with endarterectomy. Several devices have been developed to reduce or detect emboli that may be dislodged during carotid artery stenting (CAS) to treat carotid artery stenosis. A significant challenge in assessing the efficacy of these devices is precisely determining when emboli are dislodged in real-time. To address this challenge, we devised a method of simultaneously recording fluoroscopic images, transcranial Doppler (TCD) data, vital signs, and digital video of the patient/physician. This method permits accurate causative analysis and allows procedural events to be precisely correlated to embolic events in real-time. PMID:21441834

  8. Coulomb time delays in high harmonic generation

    NASA Astrophysics Data System (ADS)

    Torlina, Lisa; Smirnova, Olga

    2017-02-01

    Measuring the time it takes to remove an electron from an atom or molecule during photoionization has been the focus of a number of recent experiments using newly developed attosecond spectroscopies. The interpretation of such measurements, however, depends critically on the measurement protocol and the specific observables available in each experiment. One such protocol relies on high harmonic generation. In this paper, we derive rigorous and general expressions for ionisation and recombination times in high harmonic generation experiments. We show that these times are different from, but related to, ionisation times measured in photoelectron spectroscopy: that is, those obtained using the attosecond streak camera, RABBITT and attoclock methods. We then proceed to use the analytical R-matrix theory to calculate these times and compare them with experimental values.

  9. Web-based access to near real-time and archived high-density time-series data: cyber infrastructure challenges & developments in the open-source Waveform Server

    NASA Astrophysics Data System (ADS)

    Reyes, J. C.; Vernon, F. L.; Newman, R. L.; Steidl, J. H.

    2010-12-01

    The Waveform Server is an interactive web-based interface to multi-station, multi-sensor and multi-channel high-density time-series data stored in Center for Seismic Studies (CSS) 3.0 schema relational databases (Newman et al., 2009). In the last twelve months, based on expanded specifications and current user feedback, both the server-side infrastructure and client-side interface have been extensively rewritten. The Python Twisted server-side code-base has been fundamentally modified to now present waveform data stored in cluster-based databases using a multi-threaded architecture, in addition to supporting the pre-existing single database model. This allows interactive web-based access to high-density (broadband @ 40Hz to strong motion @ 200Hz) waveform data that can span multiple years; the common lifetime of broadband seismic networks. The client-side interface expands on it's use of simple JSON-based AJAX queries to now incorporate a variety of User Interface (UI) improvements including standardized calendars for defining time ranges, applying on-the-fly data calibration to display SI-unit data, and increased rendering speed. This presentation will outline the various cyber infrastructure challenges we have faced while developing this application, the use-cases currently in existence, and the limitations of web-based application development.

  10. Application of a multi-channel microfluidic chip on the simultaneous detection of DNAs by using microbead-quantum dots.

    PubMed

    Le, Ngoc Tam; Kim, Jong Sung

    2014-12-01

    Several researches have shown that cancer is caused by genetic mutations especially in genes involved in cell growth and regulation. Ras family members are frequently found in their mutated, oncogenic forms in human tumors. Mutant RAS proteins are constitutively active, owing to reduce intrinsic GTPase activity and insensitivity to GTPase-activating protein (GAPs). In total, activating mutations in the RAS genes occur in approximately 20% of all human cancers, mainly in codon 12, 13 or 61. Activating mutations in the NRAS gene not only result in the reduction of intrinsic GTPase activity but also in the induction of resistance against molecules inducing such activity. In this paper, we reported a rapid, simple and portable method for detecting the mutant types of NRAS genes codon 12 and 61 simultaneously by using bead-quantum dots (QDs) based multi-channel microfluidic chip. Probe DNAs are conjugated to bead-QDs and packed in the pillars of channels in the microfluidic chip. After injection of target DNAs and intercalating dyes, the fluorescence quenching of QDs by intercalating dye was observed due to FRET phenomena. The platform can be effortlessly applied in other biological and clinical areas.

  11. Intravital imaging of mouse colonic adenoma using MMP-based molecular probes with multi-channel fluorescence endoscopy.

    PubMed

    Oh, Gyungseok; Yoo, Su Woong; Jung, Yebin; Ryu, Yeon-Mi; Park, Youngrong; Kim, Sang-Yeob; Kim, Ki Hean; Kim, Sungjee; Myung, Seung-Jae; Chung, Euiheon

    2014-05-01

    Intravital imaging has provided molecular, cellular and anatomical insight into the study of tumor. Early detection and treatment of gastrointestinal (GI) diseases can be enhanced with specific molecular markers and endoscopic imaging modalities. We present a wide-field multi-channel fluorescence endoscope to screen GI tract for colon cancer using multiple molecular probes targeting matrix metalloproteinases (MMP) conjugated with quantum dots (QD) in AOM/DSS mouse model. MMP9 and MMP14 antibody (Ab)-QD conjugates demonstrate specific binding to colonic adenoma. The average target-to-background (T/B) ratios are 2.10 ± 0.28 and 1.78 ± 0.18 for MMP14 Ab-QD and MMP9 Ab-QD, respectively. The overlap between the two molecular probes is 67.7 ± 8.4%. The presence of false negative indicates that even more number of targeting could increase the sensitivity of overall detection given heterogeneous molecular expression in tumors. Our approach indicates potential for the screening of small or flat lesions that are precancerous.

  12. Benchmarking and qualification of the NUFREQ-NPW code for best estimate prediction of multi-channel core stability margins

    SciTech Connect

    Taleyarkhan, R.; Lahey, R.T. Jr.; McFarlane, A.F.; Podowski, M.Z.

    1988-01-01

    The NUFREQ-NPW code was modified and set up at Westinghouse, USA for mixed fuel type multi-channel core-wide stability analysis. The resulting code, NUFREQ-NPW, allows for variable axial power profiles between channel groups and can handle mixed fuel types. Various models incorporated into NUFREQ-NPW were systematically compared against the Westinghouse channel stability analysis code MAZDA-NF, for which the mathematical model was developed, in an entirely different manner. Excellent agreement was obtained which verified the thermal-hydraulic modeling and coding aspects. Detailed comparisons were also performed against nuclear-coupled reactor core stability data. All thirteen Peach Bottom-2 EOC-2/3 low flow stability tests were simulated. A key aspect for code qualification involved the development of a physically based empirical algorithm to correct for the effect of core inlet flow development on subcooled boiling. Various other modeling assumptions were tested and sensitivity studies performed. Good agreement was obtained between NUFREQ-NPW predictions and data. Moreover, predictions were generally on the conservative side. The results of detailed direct comparisons with experimental data using the NUFREQ-NPW code; have demonstrated that BWR core stability margins are conservatively predicted, and all data trends are captured with good accuracy. The methodology is thus suitable for BWR design and licensing purposes. 11 refs., 12 figs., 2 tabs.

  13. Hypofrontality in panic disorder and major depressive disorder assessed by multi-channel near-infrared spectroscopy.

    PubMed

    Ohta, Haruhisa; Yamagata, Bun; Tomioka, Hiroi; Takahashi, Taro; Yano, Madoka; Nakagome, Kazuyuki; Mimura, Masaru

    2008-01-01

    Panic disorder is a common and debilitating psychiatric disease; yet, the neurobiology of this disorder is not fully understood. Deficits in the prefrontal inhibitory control over hyperactivity of the anxiety-related neural circuit are implicated in the pathophysiological core of panic disorder. The aims of this study were to investigate whether panic disorder reveals frontal lobe dysfunction while performing the word fluency test by using multi-channel near-infrared spectroscopy and to compare the findings in panic disorder with those in major depressive disorder. Twenty-one patients with panic disorder, 17 patients with major depressive disorder, and 24 healthy control subjects participated in the study. Both patients with panic disorder and with major depressive disorder showed similarly attenuated increases in oxy-hemoglobin during the word fluency test in the bilateral frontal regions, when compared to healthy control participants. Hypofrontality in panic disorder and major depressive disorder was most prominent in the left medial inferior frontal lobe. This study clarified that hypofrontality in panic disorder is evident even with neutral stimuli of little emotional load.

  14. Development of the RF Front-end of a Multi-Channel Microwave Radiometer for Internal Body Temperature Measurements

    NASA Astrophysics Data System (ADS)

    Karabetsos, Sotiris; Koulouras, Grigorios; Charamis, Panagiotis; Adamidis, George; Vardiambasis, Ioannis O.; Nassiopoulos, Athanasios

    2015-09-01

    Microwave Thermograph (MT) is based on measuring the electromagnetic field spontaneously emitted by a body in micro-wave frequency range. In microwave radiometers, temperature measurement is made by measuring the thermal noise power. The primary module that is used for detecting this thermal noise power is the RF Front-end, which must meet very challenging requirements in terms of accuracy for measuring the noise power at the input of the receiver. The work that will be presented here will exhibit the design approaches and specifications as well as the trade-offs and performance criteria towards the development and prototyping of the RF Front-end for a Multi-Channel Microwave Radiometer for internal body temperature measurements in the l-4GHz frequency bands. The RF Front-end is intended to be integrated and be a part of a full Microwave Radiometer device that targets early detection of malignant tumours. The latter relate with the increase of temperature in cancerous cells and the precise detection of the temperature difference, which is the goal of the radiometer.

  15. Functional connectivity during phonemic and semantic verbal fluency test: a multi-channel near infrared spectroscopy study (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Huang, Chun-Jung; Sun, Chia-Wei; Chou, Po-Han; Chuang, Ching-Cheng

    2016-03-01

    Verbal fluency tests (VFT) are widely used neuropsychological tests of frontal lobe and have been frequently used in various functional brain mapping studies. There are two versions of VFT based on the type of cue: the letter fluency task (LFT) and the category fluency task (CFT). However, the fundamental aspect of the brain connectivity across spatial regions of the fronto-temporal regions during the VFTs has not been elucidated to date. In this study we hypothesized that different cortical functional connectivity over bilateral fronto-temporal regions can be observed by means of multi-channel fNIRS in the LFT and the CFT respectively. Our results from fNIRS (ETG-4000) showed different patterns of brain functional connectivity consistent with these different cognitive requirements. We demonstrate more brain functional connectivity over frontal and temporal regions during LFT than CFT, and this was in line with previous brain activity studies using fNIRS demonstrating increased frontal and temporal region activation during LFT and CFT and more pronounced frontal activation by the LFT.

  16. A Multi-channel Semicircular Canal Neural Prosthesis Using Electrical Stimulation to Restore 3D Vestibular Sensation

    PubMed Central

    Della Santina, Charles C.; Migliaccio, Americo A.; Patel, Amit H.

    2009-01-01

    Bilateral loss of vestibular sensation can be disabling. Those afflicted suffer illusory visual field movement during head movements, chronic disequilibrium and postural instability due to failure of vestibulo-ocular and vestibulo-spinal reflexes. A neural prosthesis that emulates the normal transduction of head rotation by semicircular canals could significantly improve quality of life for these patients. Like the 3 semicircular canals in a normal ear, such a device should at least transduce 3 orthogonal (or linearly separable) components of head rotation into activity on corresponding ampullary branches of the vestibular nerve. We describe the design, circuit performance and in vivo application of a head-mounted, semi-implantable multi-channel vestibular prosthesis that encodes head movement in 3 dimensions as pulse-frequency-modulated electrical stimulation of 3 or more ampullary nerves. In chinchillas treated with intratympanic gentamicin to ablate vestibular sensation bilaterally, prosthetic stimuli elicited a partly compensatory angular vestibulo-ocular reflex in multiple planes. Minimizing misalignment between the axis of eye and head rotation, apparently caused by current spread beyond each electrode’s targeted nerve branch, emerged as a key challenge. Increasing stimulation selectivity via improvements in electrode design, surgical technique and stimulus protocol will likely be required to restore AVOR function over the full range of normal behavior. PMID:17554821

  17. Equalization enhanced phase noise in Nyquist-spaced superchannel transmission systems using multi-channel digital back-propagation.

    PubMed

    Xu, Tianhua; Liga, Gabriele; Lavery, Domaniç; Thomsen, Benn C; Savory, Seb J; Killey, Robert I; Bayvel, Polina

    2015-09-14

    Superchannel transmission spaced at the symbol rate, known as Nyquist spacing, has been demonstrated for effectively maximizing the optical communication channel capacity and spectral efficiency. However, the achievable capacity and reach of transmission systems using advanced modulation formats are affected by fibre nonlinearities and equalization enhanced phase noise (EEPN). Fibre nonlinearities can be effectively compensated using digital back-propagation (DBP). However EEPN which arises from the interaction between laser phase noise and dispersion cannot be efficiently mitigated, and can significantly degrade the performance of transmission systems. Here we report the first investigation of the origin and the impact of EEPN in Nyquist-spaced superchannel system, employing electronic dispersion compensation (EDC) and multi-channel DBP (MC-DBP). Analysis was carried out in a Nyquist-spaced 9-channel 32-Gbaud DP-64QAM transmission system. Results confirm that EEPN significantly degrades the performance of all sub-channels of the superchannel system and that the distortions are more severe for the outer sub-channels, both using EDC and MC-DBP. It is also found that the origin of EEPN depends on the relative position between the carrier phase recovery module and the EDC (or MC-DBP) module. Considering EEPN, diverse coding techniques and modulation formats have to be applied for optimizing different sub-channels in superchannel systems.

  18. Equalization enhanced phase noise in Nyquist-spaced superchannel transmission systems using multi-channel digital back-propagation

    PubMed Central

    Xu, Tianhua; Liga, Gabriele; Lavery, Domaniç; Thomsen, Benn C.; Savory, Seb J.; Killey, Robert I.; Bayvel, Polina

    2015-01-01

    Superchannel transmission spaced at the symbol rate, known as Nyquist spacing, has been demonstrated for effectively maximizing the optical communication channel capacity and spectral efficiency. However, the achievable capacity and reach of transmission systems using advanced modulation formats are affected by fibre nonlinearities and equalization enhanced phase noise (EEPN). Fibre nonlinearities can be effectively compensated using digital back-propagation (DBP). However EEPN which arises from the interaction between laser phase noise and dispersion cannot be efficiently mitigated, and can significantly degrade the performance of transmission systems. Here we report the first investigation of the origin and the impact of EEPN in Nyquist-spaced superchannel system, employing electronic dispersion compensation (EDC) and multi-channel DBP (MC-DBP). Analysis was carried out in a Nyquist-spaced 9-channel 32-Gbaud DP-64QAM transmission system. Results confirm that EEPN significantly degrades the performance of all sub-channels of the superchannel system and that the distortions are more severe for the outer sub-channels, both using EDC and MC-DBP. It is also found that the origin of EEPN depends on the relative position between the carrier phase recovery module and the EDC (or MC-DBP) module. Considering EEPN, diverse coding techniques and modulation formats have to be applied for optimizing different sub-channels in superchannel systems. PMID:26365422

  19. Gait training assisted by multi-channel functional electrical stimulation early after stroke: study protocol for a randomized controlled trial.

    PubMed

    van Bloemendaal, Maijke; Bus, Sicco A; de Boer, Charlotte E; Nollet, Frans; Geurts, Alexander C H; Beelen, Anita

    2016-10-01

    Many stroke survivors suffer from paresis of lower limb muscles, resulting in compensatory gait patterns characterised by asymmetries in spatial and temporal parameters and reduced walking capacity. Functional electrical stimulation has been used to improve walking capacity, but evidence is mostly limited to the orthotic effects of peroneal functional electrical stimulation in the chronic phase after stroke. The aim of this study is to investigate the therapeutic effects of up to 10 weeks of multi-channel functional electrical stimulation (MFES)-assisted gait training on the restoration of spatiotemporal gait symmetry and walking capacity in subacute stroke patients. In a proof-of-principle study with a randomised controlled design, 40 adult patients with walking deficits who are admitted for inpatient rehabilitation within 31 days since the onset of stroke are randomised to either MFES-assisted gait training or conventional gait training. Gait training is delivered in 30-minute sessions each workday for up to 10 weeks. The step length symmetry ratio is the primary outcome. Blinded assessors conduct outcome assessments at baseline, every 2 weeks during the intervention period, immediately post intervention and at 3-month follow-up. This study aims to provide preliminary evidence for the feasibility and effectiveness of MFES-assisted gait rehabilitation early after stroke. Results will inform the design of a larger multi-centre trial. This trial is registered at the Netherlands Trial Register (number NTR4762 , registered 28 August 2014).

  20. Pitch control of multi-channel graded-index core polymer waveguide for optical PCB using the Mosquito method

    NASA Astrophysics Data System (ADS)

    Kinoshita, Ryota; Suganuma, Daisuke; Ishigure, Takaaki

    2014-03-01

    We successfully fabricate multi-channel GI circular-core polymer waveguides with precisely controlled pitches utilizing the Mosquito method. The Mosquito method is a very simple method for fabricating GI-core polymer optical waveguides that utilizes a micro dispenser. In this method, a viscous core monomer is directly dispensed into a cladding monomer layer before UV cured, and circular cores are formed by curing both the core and cladding under a UV exposure. Here, it is a concern that a needle position accuracy influences on the interchannel pitch when parallel cores are fabricated by parallel repetitive scan of a single needle. However, we succeeded in controlling the pitch with the Mosquito method and then, GI-core waveguides with 250.7+/-5.2 μm, 126.7+/-2.6 μm and 61.7+/-3.4 μm are successfully fabricated for the pre-set values of 250 μm, 125 μm and 62.5 μm, respectively. Then, we demonstrate a 4 × 10 Gbps transmission over the fabricated GI-core waveguide by connecting the waveguide to an MMF ribbon with a 250-μm pitch, which is realized because the pitch of the fabricated waveguide is accurately controlled to 250 μm.

  1. Equalization enhanced phase noise in Nyquist-spaced superchannel transmission systems using multi-channel digital back-propagation

    NASA Astrophysics Data System (ADS)

    Xu, Tianhua; Liga, Gabriele; Lavery, Domaniç; Thomsen, Benn C.; Savory, Seb J.; Killey, Robert I.; Bayvel, Polina

    2015-09-01

    Superchannel transmission spaced at the symbol rate, known as Nyquist spacing, has been demonstrated for effectively maximizing the optical communication channel capacity and spectral efficiency. However, the achievable capacity and reach of transmission systems using advanced modulation formats are affected by fibre nonlinearities and equalization enhanced phase noise (EEPN). Fibre nonlinearities can be effectively compensated using digital back-propagation (DBP). However EEPN which arises from the interaction between laser phase noise and dispersion cannot be efficiently mitigated, and can significantly degrade the performance of transmission systems. Here we report the first investigation of the origin and the impact of EEPN in Nyquist-spaced superchannel system, employing electronic dispersion compensation (EDC) and multi-channel DBP (MC-DBP). Analysis was carried out in a Nyquist-spaced 9-channel 32-Gbaud DP-64QAM transmission system. Results confirm that EEPN significantly degrades the performance of all sub-channels of the superchannel system and that the distortions are more severe for the outer sub-channels, both using EDC and MC-DBP. It is also found that the origin of EEPN depends on the relative position between the carrier phase recovery module and the EDC (or MC-DBP) module. Considering EEPN, diverse coding techniques and modulation formats have to be applied for optimizing different sub-channels in superchannel systems.

  2. Intravital imaging of mouse colonic adenoma using MMP-based molecular probes with multi-channel fluorescence endoscopy

    PubMed Central

    Oh, Gyungseok; Yoo, Su Woong; Jung, Yebin; Ryu, Yeon-Mi; Park, Youngrong; Kim, Sang-Yeob; Kim, Ki Hean; Kim, Sungjee; Myung, Seung-Jae; Chung, Euiheon

    2014-01-01

    Intravital imaging has provided molecular, cellular and anatomical insight into the study of tumor. Early detection and treatment of gastrointestinal (GI) diseases can be enhanced with specific molecular markers and endoscopic imaging modalities. We present a wide-field multi-channel fluorescence endoscope to screen GI tract for colon cancer using multiple molecular probes targeting matrix metalloproteinases (MMP) conjugated with quantum dots (QD) in AOM/DSS mouse model. MMP9 and MMP14 antibody (Ab)-QD conjugates demonstrate specific binding to colonic adenoma. The average target-to-background (T/B) ratios are 2.10 ± 0.28 and 1.78 ± 0.18 for MMP14 Ab-QD and MMP9 Ab-QD, respectively. The overlap between the two molecular probes is 67.7 ± 8.4%. The presence of false negative indicates that even more number of targeting could increase the sensitivity of overall detection given heterogeneous molecular expression in tumors. Our approach indicates potential for the screening of small or flat lesions that are precancerous. PMID:24877024

  3. A multi-channel image reconstruction method for grating-based X-ray phase-contrast computed tomography

    NASA Astrophysics Data System (ADS)

    Xu, Qiaofeng; Sawatzky, Alex; Anastasio, Mark A.

    2014-03-01

    In this work, we report on the development of an advanced multi-channel (MC) image reconstruction algorithm for grating-based X-ray phase-contrast computed tomography (GB-XPCT). The MC reconstruction method we have developed operates by concurrently, rather than independently as is done conventionally, reconstructing tomographic images of the three object properties (absorption, small-angle scattering, refractive index). By jointly estimating the object properties by use of an appropriately defined penalized weighted least squares (PWLS) estimator, the 2nd order statistical properties of the object property sinograms, including correlations between them, can be fully exploited to improve the variance vs. resolution tradeoff of the reconstructed images as compared to existing methods. Channel-independent regularization strategies are proposed. To solve the MC reconstruction problem, we developed an advanced algorithm based on the proximal point algorithm and the augmented Lagrangian method. By use of experimental and computer-simulation data, we demonstrate that by exploiting inter-channel noise correlations, the MC reconstruction method can improve image quality in GB-XPCT.

  4. A 12-bit 1 MS/s SAR-ADC for multi-channel CdZnTe detectors

    NASA Astrophysics Data System (ADS)

    Wei, Liu; Tingcun, Wei; Bo, Li; Panjie, Guo; Yongcai, Hu

    2015-04-01

    This paper presents a low power, area-efficient and radiation-hardened 12-bit 1 MS/s successive approximation register (SAR) analog-to-digital converter (ADC) for multi-channel CdZnTe (CZT) detector applications. In order to improve the SAR-ADC's accuracy, a novel comparator is proposed in which the offset voltage is self-calibrated and also a new architecture for the unit capacitor array is proposed to reduce the capacitance mismatches in the charge-redistribution DAC. The ability to radiation-harden the SAR-ADC is enhanced through circuit and layout design technologies. The prototype chip was fabricated using a TSMC 0.35 μm 2P4M CMOS process. At a 3.3/5 V power supply and a sampling rate of 1 MS/s, the proposed SAR-ADC achieves a peak signal to noise and distortion ratio (SINAD) of 67.64 dB and consumes only 10 mW power. The core of the prototype chip occupies an active area of 1180 × 1080 μm2. Project supported by the Special-Funded Program on National Key Scientific Instruments and Equipment Development (No. 2011YQ040082).

  5. Evaluation of the potential of soil remediation by direct multi-channel pulsed corona discharge in soil.

    PubMed

    Wang, Tie Cheng; Qu, Guangzhou; Li, Jie; Liang, Dongli

    2014-01-15

    A novel approach, named multi-channel pulsed corona discharge in soil, was developed for remediating organic pollutants contaminated soil, with p-nitrophenol (PNP) as the model pollutant. The feasibility of PNP degradation in soil was explored by evaluating effects of pulse discharge voltage, air flow rate and soil moisture on PNP degradation. Based on roles of chemically active species and evolution of degradation intermediates, PNP degradation processes were discussed. Experimental results showed that about 89.4% of PNP was smoothly degraded within 60min of discharge treatment at pulse discharge voltage 27kV, soil moisture 5% and air flow rate 0.8Lmin(-1), and the degradation process fitted the first-order kinetic model. Increasing pulse discharge voltage was found to be favorable for PNP degradation, but not for energy yield. There existed appropriate air flow rate and soil moisture for obtaining gratifying PNP degradation efficacy. Roles of radical scavenger and measurement of active species suggested that ozone, H2O2, and OH radicals played very important roles in PNP degradation. CN bond in PNP molecule was cleaved, and the main intermediate products such as hydroquinone, benzoquinone, catechol, phenol, acetic acid, formic acid, oxalic acid, NO2(-) and NO3(-) were identified. Possible pathway of PNP degradation in soil in such a system was proposed.

  6. Precision timing measurements for high energy photons

    SciTech Connect

    Anderson, Dustin; Apreysan, Artur; Bornheim, Adi; Duarte, Javier; Newman, Harvey; Pena, Cristian; Ronzhin, Anatoly; Spiropulu, Maria; Trevor, Jason; Xie, Si; Zhu, Ren-Yuan

    2014-11-21

    Particle colliders operating at high luminosities present challenging environments for high energy physics event reconstruction and analysis. We discuss how timing information, with a precision on the order of 10 ps, can aid in the reconstruction of physics events under such conditions. We present calorimeter based timing measurements from test beam experiments in which we explore the ultimate timing precision achievable for high energy photons or electrons of 10 GeV and above. Using a prototype calorimeter consisting of a 1.7×1.7×1.7 cm3 lutetium–yttrium oxyortho-silicate (LYSO) crystal cube, read out by micro-channel plate photomultipliers, we demonstrate a time resolution of 33.5±2.1 ps for an incoming beam energy of 32 GeV. In a second measurement, using a 2.5×2.5×20 cm3 LYSO crystal placed perpendicularly to the electron beam, we achieve a time resolution of 59±11 ps using a beam energy of 4 GeV. We also present timing measurements made using a shashlik-style calorimeter cell made of LYSO and tungsten plates, and demonstrate that the apparatus achieves a time resolution of 54±5 ps for an incoming beam energy of 32 GeV.

  7. Fetal cardiac activity analysis during twin pregnancy using a multi-channel SQUID system

    NASA Astrophysics Data System (ADS)

    Costa Monteiro, E.; Schleussner, E.; Kausch, S.; Grimm, B.; Schneider, A.; Hall Barbosa, C.; Haueisen, J.

    2001-05-01

    The use of SQUID magnetometers for non-invasive in utero assessment of cardiac electrical disturbances has already been shown to be a valuable clinical tool. In this way, its applicability also for the complicated case of twin pregnancy, in which the proximity of the cardiac magnetic source of each fetus can hamper the individual analysis of cardiac electrical activity, is of clinical interest. In this paper, we present fetal magnetocardiography performed on a mother pregnant of twins with 26 weeks gestational age, measured inside a magnetically shielded room, by using two identical 31-channel low- Tc SQUID magnetometer systems. Each sensor array has been positioned over one of the fetuses, according to its heart position previously assessed with the aid of ultrasound measurements. The raw data is initially averaged in time and, afterwards, analyzed by means of time plots and isofield maps. The time recordings allow the study of the morphology of each fetus’ cardiac signal and the cardiac time intervals. The resultant equivalent dipole obtained from the isofield maps indicates the position and orientation of each fetus heart. The results agree with the ultrasound analysis performed immediately before the measurements and used to obtain the approximate location of the fetuses’ hearts. Since a distinct analysis of the cardiac electrical activity of each fetus could be achieved, the results indicate the potential of the fetal magnetocardiography in the individual antenatal diagnosis of each one of the fetuses of a twin pregnancy.

  8. An oject oriented environment for multi-channel signal analysis and understanding

    SciTech Connect

    Maurer, W.J.; Dowla, F.U.

    1994-11-15

    We describe an interactive signal analysis an understanding tool for multichannel signals. The system, written entirely in the C++ language, takes full advantage of the modern workstation GUI tools and integrates traditional signal-processing methods with intelligent domain-specific tools for the exploration and analysis of semistructured problems. By semistructured problems, we mean problems that require a high degree of interactive analysis, and further, the analysis steps are highly adaptive. In other words, a finite number of rules cannot be used to obtain a good solution to the problem.

  9. A Novel Multi-Channel MAC Protocol for Cluster Based Wireless Multimedia Sensor Networks

    NASA Astrophysics Data System (ADS)

    Wei, Lu; Longmei, Zhang

    An energy efficient, scalable and collision free MAC protocol, DTFMM, is presented in this paper, which combines frequency and time division principles for medium sharing. It is based on clustered network topology, and the protocol employs a distributed local coordinate algorithm for assigning channels among clusters to enable simultaneous non-interfering data collection. Intra-cluster transmissions are scheduled by cluster head (CH) based on time slot. CHs aggregate the gathered data and forward it over inter-CH paths to the base-station based on minimum spanning tree routing. Distinct channels are adopted by the independent branches of the inter-CH routing tree. Data transmission on a branch is further scheduled in depth-first ordering. DTFMM allows nodes to stay in sleeping mode for the longest duration and thus it minimizes energy consumption. Simulation demonstrated superiority of DTFMM in terms of convergent rate, throughput and delay performance when compared with well-known protocol MMSN.

  10. Equations of Motion of a Ground Moving Target for a Multi-Channel Spaceborne SAR

    DTIC Science & Technology

    2009-03-01

    function of the receive phase center index p (= 1, 2, 3, etc.) along the antenna and the pulse (or slow) time t: Rp(t) = R0 +(p−1)D(Ψ−Φ0)+(Vtr − Vsr )(t...radial acceleration component. R0, Φ0, Vtr, Vta, and Atr are defined for time t0. Vsr depends onVs and Φ0 in a predictable way. Vs,Vg, andVe vary slowly...l’impulsion (lent) : Rp(t) = R0 +(p−1)D(Ψ−Φ0)+(Vtr − Vsr )(t − t0) + (p−1)D R0 (Vta −Vg)(t − t0)+ 1 2 ( V 2e −2VsVta R0 +Atr ) (t − t0) 2 Les équations

  11. Developing fetal motor-cardiovascular coordination analyzed from multi-channel magnetocardiography.

    PubMed

    Schmidt, A; Schneider, U; Witte, O W; Schleußner, E; Hoyer, D

    2014-10-01

    Fetal movements (FM) related heart rate accelerations (AC) are an important maturation criterion. Since Doppler-based time resolution is not sufficient for accompanying heart rate variability analysis, the work is aimed at a comprehensive FM-AC analysis using magnetocardiographic recordings from fetuses during sleep.We identify FM and AC by independent component analysis and automatic recognition algorithms. We investigate associations between FM and AC of different magnitude by means of event coincidence and time series cross-correlation over the maturation period of 21-40 weeks of gestation (WGA).FM related AC appear with increasing AC magnitude and WGA. Vice versa, AC related FM appear independent of WGA, but more frequently with increasing AC amplitude. The FM-AC correlation exists already at 21 WGA and further increases with WGA while the variability of its time delay decreases. Hence, FM and AC are clearly associated over the whole investigated maturation period. The increase of FM related AC runs parallel to the increasing AC magnitude.The MCG methodology was confirmed and results from previous Doppler-based analyses reproduced. Hence, MCG recordings allow the collective analysis of heart rate variability based maturation indices and FM related AC. This synergism may improve the diagnosis of fetal developmental disorders.

  12. Design study for multi-channel tape recorder system, volume 1

    NASA Technical Reports Server (NTRS)

    1972-01-01

    The means of storing multispectral, high resolution sensor data on an Earth observing satellite are studied. It is concluded that this is best done digitally on a multi-track, longitudinal, magnetic tape recorder. The machine proposed will store 8 X 10 to the 10th power bits of data on 1040 m of 51 mm-wide magnetic tape mounted on two co-planar reels.

  13. Field test results with the targeted search MCSA. [multi-channel spectrum analyzer for SETI

    NASA Technical Reports Server (NTRS)

    Tarter, J. C.

    1988-01-01

    In April 1985, a 74,000 channel prototype of the multichannel spectrum analyzer (MCSA) that NASA plans to use in a systematic search for extraterrestrial intelligence (SETI) was installed at DSS13, a 26 meter R&D antenna facility at the Goldstone Deep Space Network (DSN) site. Since that time the instrumentation has been used to validate the performance of signal detection algorithms using locally injected signals and the weak carriers from distant spacecraft. This paper describes results from the Goldstone Field Tests and plans to move the prototype equipment to other sites where SETI may be conducted in the future.

  14. Joint Spectrum Allocation and Scheduling in Multi-Radio Multi-Channel Cognitive Radio Wireless Networks

    DTIC Science & Technology

    2010-04-01

    radios in node y. The time required to solve this problem can be significantly decreased if a greedy clique decomposition of the conflict graph is...performed. Specifically, a set of cliques © Qi, i = 1, 2, ...Q ª are found such that if yj ∈ χ (xk), then there is a clique Qi such that xk ∈ Qi and yj ∈ Qi...and trace files. The propagation simulator is based on ray -tracing and accounts for reflections off of the ground and off of buildings, transmission

  15. Field test results with the targeted search MCSA. [multi-channel spectrum analyzer for SETI

    NASA Technical Reports Server (NTRS)

    Tarter, J. C.

    1988-01-01

    In April 1985, a 74,000 channel prototype of the multichannel spectrum analyzer (MCSA) that NASA plans to use in a systematic search for extraterrestrial intelligence (SETI) was installed at DSS13, a 26 meter R&D antenna facility at the Goldstone Deep Space Network (DSN) site. Since that time the instrumentation has been used to validate the performance of signal detection algorithms using locally injected signals and the weak carriers from distant spacecraft. This paper describes results from the Goldstone Field Tests and plans to move the prototype equipment to other sites where SETI may be conducted in the future.

  16. Multi-channel MRI segmentation with graph cuts using spectral gradient and multidimensional Gaussian mixture model

    NASA Astrophysics Data System (ADS)

    Lecoeur, Jérémy; Ferré, Jean-Christophe; Collins, D. Louis; Morrisey, Sean P.; Barillot, Christian

    2009-02-01

    A new segmentation framework is presented taking advantage of multimodal image signature of the different brain tissues (healthy and/or pathological). This is achieved by merging three different modalities of gray-level MRI sequences into a single RGB-like MRI, hence creating a unique 3-dimensional signature for each tissue by utilising the complementary information of each MRI sequence. Using the scale-space spectral gradient operator, we can obtain a spatial gradient robust to intensity inhomogeneity. Even though it is based on psycho-visual color theory, it can be very efficiently applied to the RGB colored images. More over, it is not influenced by the channel assigment of each MRI. Its optimisation by the graph cuts paradigm provides a powerful and accurate tool to segment either healthy or pathological tissues in a short time (average time about ninety seconds for a brain-tissues classification). As it is a semi-automatic method, we run experiments to quantify the amount of seeds needed to perform a correct segmentation (dice similarity score above 0.85). Depending on the different sets of MRI sequences used, this amount of seeds (expressed as a relative number in pourcentage of the number of voxels of the ground truth) is between 6 to 16%. We tested this algorithm on brainweb for validation purpose (healthy tissue classification and MS lesions segmentation) and also on clinical data for tumours and MS lesions dectection and tissues classification.

  17. A multi-channel monolithic Ge detector system for fluorescence x-ray absorption spectroscopy

    SciTech Connect

    Bucher, J.J.; Allen, P.G.; Edelstein, N.M.; Shuh, D.K.; Madden, N.W.; Cork, C.; Luke, P.; Pehl, D.; Malone, D.

    1995-03-01

    Construction and performance of a monolithic quad-pixel Ge detector for fluorescence x-ray absorption spectroscopy (XAS) at synchrotron radiation sources are described. The detector semiconductor element has an active surface area of 4.0 cm{sup 2} which is electrically separated into four 1.0 cm{sup 2} pixels, with little interfacial dead volume. Spatial response of the array shows that cross-talk between adjacent pixels is < 10% for 5.9 keV photons that fall within 0.5 mm of the pixel boundaries. The detector electronics system uses pre-amplifiers built at LBNL with commercial Tennelec Model TC 244 amplifiers. Using an {sup 55}Fe test source (MnK{sub {alpha}}, 5.9 keV), energy resolution of better than 200 eV is achieved with a 4 {mu}sec peaking time. At 0.5 {mu}sec peaking time, pulse pileup results in a 75% throughput efficiency for an incoming count rate of 100 kHz. Initial XAS fluoresncece measurements at the beamline 4 wiggler end stations at SSRL show that the detector system has several advantages over commercial x-ray spectrometers for low-concentration counting.

  18. Identification of motion from multi-channel EMG signals for control of prosthetic hand.

    PubMed

    Geethanjali, P; Ray, K K

    2011-09-01

    The authors in this paper propose an effective and efficient pattern recognition technique from four channel electromyogram (EMG) signals for control of multifunction prosthetic hand. Time domain features such as mean absolute value, number of zero crossings, number of slope sign changes and waveform length are considered for pattern recognition. The patterns are classified using simple logistic regression (SLR) technique and decision tree (DT) using J48 algorithm. In this study six specific hand and wrist motions are identified from the EMG signals obtained from ten different able-bodied. By considering relevant dominant features for pattern recognition, the processing time as well as memory space of the SLR and DT classifiers is found to be less in comparison with neural network (NN), k-nearest neighbour model 1 (kNN-Model-1), k-nearest neighbour model 2 (kNN-Model-2) and linear discriminant analysis. The classification accuracy of SLR classifier is found to be 91 ± 1.9%.

  19. Foetal magnetocardiography with a multi-channel HTS rf SQUID gradiometer

    NASA Astrophysics Data System (ADS)

    Zhang, Y.; Wolters, N.; Lomparski, D.; Zander, W.; Banzet, M.; Schubert, J.; Krause, H.-J.; Geue, D.; van Leeuwen, P.

    2006-05-01

    Foetal magnetocardiography (fMCG) is a promising technique for prenatal cardiac diagnosis. In this paper, we discuss the special requirements of a system for fMCG measurements. A SQUID system incorporating five HTS rf SQUID magnetometers has been developed and constructed. Four magnetometers are arranged at the bottom of the cryostat in a 4 cm × 4 cm square configuration. One reference magnetometer is located 20 cm above the plane to form four first-order axial gradiometers with the four bottom magnetometers. The magnetometer with a 18 mm diameter flux focuser, which reaches a field sensitivity of 20-30 fT Hz-1/2, proved sufficient for recording foetal magnetocardiograms in a magnetically shielded room. The cardiac activities of two foetuses (31st and 33rd weeks of gestation) were recorded in 90 Hz bandwidth. The foetal QRS peak signals ranged from 4 to 7 pT and could easily be identified in the real-time gradiometer outputs with a signal-to-noise ratio of up to five. Furthermore, the averaged fMCG data enabled the determination of de- and repolarization time intervals. Overall, the fMCG signals proved of sufficient quality to perform foetal heart diagnostics.

  20. Low noise multi-channel biopotential wireless data acquisition system for dry electrodes

    NASA Astrophysics Data System (ADS)

    Pandian, P. S.; Whitchurch, Ashwin K.; Abraham, Jose K.; Bhusan Baskey, Himanshu; Radhakrishnan, J. K.; Varadan, Vijay K.; Padaki, V. C.; Bhasker Rao, K. U.; Harbaugh, R. E.

    2008-03-01

    The bioelectrical potentials generated within the human body are the result of electrochemical activity in the excitable cells of the nervous, muscular or glandular tissues. The ionic potentials are measured using biopotential electrodes which convert ionic potentials to electronic potentials. The commonly monitored biopotential signals are Electrocardiogram (ECG), Electroencephalogram (EEG) and Electromyogram (EMG). The electrodes used to monitor biopotential signals are Ag-AgCl and gold, which require skin preparation by means of scrubbing to remove the dead cells and application of electrolytic gel to reduce the skin contact resistance. The gels used in biopotential recordings dry out when used for longer durations and add noise to the signals and also prolonged use of gels cause irritations and rashes to skin. Also noises such as motion artifact and baseline wander are added to the biopotential signals as the electrode floats over the electrolytic gel during monitoring. To overcome these drawbacks, dry electrodes are used, where the electrodes are held against the skin surface to establish contact with the skin without the need for electrolytic fluids or gels. The major drawback associated with the dry electrodes is the high skin-electrode impedance in the low frequency range between 0.1-120 Hz, which makes it difficult to acquire clean and noise free biopotential signals. The paper presents the design and development of biopotential data acquisition and processing system to acquire biopotential signals from dry electrodes. The electrode-skin-electrode- impedance (ESEI) measurements was carried out for the dry electrodes by impedance spectroscopy. The biopotential signals are processed using an instrumentation amplifier with high CMRR and high input impedance achieved by boot strapping the input terminals. The signals are band limited by means of a second order Butterworth band pass filters to eliminate noise. The processed biopotential signals are digitized

  1. A neural signal processor for an implantable multi-channel cortical recording microsystem.

    PubMed

    Sodagar, Amir M; Wise, Kensall D; Najafi, Khalil

    2006-01-01

    A 64-channel neural processor has been developed for use in an implantable neural recording microsystem. In the scan mode, the processor is capable of detecting positive, negative, and biphasic spikes with programmable thresholds. It collects action potential information from the input channels, tags the activities with the associated channel address, compresses and finally packs the activity information in a serial digital bit stream to be sent to an external host. In the monitor mode, two channels can be selected and viewed at high resolution for studies where the entire signal is of interest.

  2. Alignment method of optical registration for multi-channel CCD camera

    NASA Astrophysics Data System (ADS)

    Xin, Jia; Yue, Guo

    2016-10-01

    The mapping satellite is use of the multichip CCD assemble technology to meet the precision landscape positioning requirements. The size of a single CCD cannot meet the requirements of modern optical system. High cost and special technology are required for the resolution. In order to apply space camera to the measurement in large field of view and high resolution, the technology of optical assembly with several CCD is discussed. And a reflector based butting system was adopted. To extend the field of view, an optical butting system is proposed. Aiming at the problems of vignette and decline of modulation transfer function caused by butting, a reflector based butting system which has nine mirrors was investigated. This paper introduced the structure design of a long array and the principle of optical butting. The basic idea of this system is to split the optical image into several parts, so that they can be detected by different sensors. The mirror is used in conventional imaging system; divide the optical image into two parts. To eliminate the vignette distortion caused by the optical system and keep high signal to noise ratio, the sensors receiving the two focal image parts are placed with a little overlapping so that they can compensate each other. In order to ensure the key techniques of mirror location accuracy, a new alignment method was proposed about locating conversation components, mainly aimed at enhancing assembly accuracy of linear array CCD.A high quality image can be obtained by butting the two image parts. Its principle, methods of adjusting and testing as well as the structure of focal plane are described. The assembly with nine TDICCDs is finished on the facility which is composed of a long work-distance microscope and a precise X-Y rail, using the method in which the mechanical adjusting is applied. Compared with convention system, this method can satisfy the linearity accuracy and overlapping pixels tolerance of 0.2 detector pixel sizes. And can

  3. Multi-channel transmit/receive metal detector coil design for vehicular applications

    NASA Astrophysics Data System (ADS)

    Yesil, Mehmet Ali; Yeǧin, Korkut; Bellikli, Hasan; Tura, Levent; Nazlı, Hakki; Daǧ, Mahmut

    2014-05-01

    Metal detector coil design has been matured to great extent over the years. However, vehicle mounted or remotely operated metal detectors require different specifications and these specifications dictate multiple transmit and receive coils operating in various settings. Unlike handheld operation, detector is more susceptible to metallic body of the vehicle. Moreover, ground calibration is also different than handheld devices. Coil geometries and intercoupling between them play a significant role in system design and performance. In this study, we study different coil geometries for vehicular applications. Starting from well-known coil geometries, we placed coils on dry, wet and ferrous soil to understand the interaction mechanism. Simulation studies are performed in frequency domain but the results are all applicable to time domain pulse based detector systems.

  4. Analysis of propagation of multi-channel EEG in the test of sustained attention.

    PubMed

    Nan, Yan; Wang, Jue; Xue, Steve An; Sheng, Hengsong; Jiao, Yongfen; Wang, Jing

    2010-01-01

    the psychological construct 'sustained attention' describes a basic component of attention characterized by the subject's readiness to detect rarely and unpredictably occurring signals over prolonged periods of time. In this study, six healthy volunteers underwent a sustained attention to response task (SART), while their electroencephalographic (EEG) were recorded contemporarily. Directed Transfer Function (DTF) was used as estimator for direction of propagation of EEG function coupling. The results of DTF showed that the information flux within EEG functional coupling changed when attention condition changed from inattention state to sustained attention state, principally at alpha and beta rhythms. The DTF could be used to evaluate sustained attention condition and they might be used for research on damage of attention mechanisms of ADHD and TBI diseases in future.

  5. Multi-Channel Magnetocardiogardiography System Based on Low-Tc SQUIDs in an Unshielded Environment

    NASA Astrophysics Data System (ADS)

    Kong, Xiangyan; Zhang, Shulin; Wang, Yongliang; Zeng, Jia; Xie, Xiaoming

    Magnetocardiography (MCG) using superconducting quantum interference devices (SQUIDs) is a new medical diagnostic tool measuring biomagnetic signals that are generated by the electrical activity of the human heart. This technique is completely passive, contactless, and it has an advantage in the early diagnosis of heart diseases. We developed the first unshielded four-channel MCG system based on low-Tc DC SQUIDs in China. Instead of using a costly magnetically shielded room, the environmental noise suppression was realized by using second-order gradiometers and three-axis reference magnetometer. The measured magnetic field resolution of the system is better than 1 pT, and multi-cycle human heart signals can be recorded directly. Also, with the infrared positioning system, 48 points data collection can be realized by moving the non-magnetic bed nine times.

  6. A multi-channel acoustics monitor for perioperative respiratory monitoring: preliminary data.

    PubMed

    Jafarian, Kamal; Amineslami, Majid; Hassani, Kamran; Navidbakhsh, Mahdi; Lahiji, Mohammad Niakan; Doyle, D John

    2016-02-01

    This study pertains to a six-channel acoustic monitoring system for use in patient monitoring during or after surgery. The base hardware consists of a USB data acquisition system, a custom-built six-channel amplification system, and a series of microphones of various designs. The software is based on the MATLAB platform with data acquisition drivers installed. The displayed information includes: time domain signals, frequency domain signals, and tools to aid in the detection of endobronchial intubation. We hypothesize that the above mentioned arrangement may be helpful to the anesthesiologist in recognizing clinical conditions like wheezing, bronchospasm, endobronchial intubation, and apnea. The study also evaluated various types of microphone designs used to transduce breath sounds. The system also features selectable band-pass filtering using MATLAB algorithms as well as a collection of recordings obtained with the system to establish what respiratory acoustic signals look like under various conditions.

  7. The suppression of coherent noise from another airgun source in marine multi-channel seismic data

    NASA Astrophysics Data System (ADS)

    Hsu, Ho-Han; Liu, Char-Shine; Chang, Jih-Hsin; Tsai, You-Tsung; Chiu, Shye-Donq

    2016-12-01

    During seismic investigations, multiple and unexpected sources may cause serious interference on seismic records, and coherent noise generated by another unwanted active source could result in extremely poor data quality. Because airgun arrays have been widely used as the sound source in marine seismic surveys, the noise generated by another airgun array usually has similar characteristics to the primary signals in both frequency bands and wave forms, so the suppression of this type of coherent noise is very difficult. In practice, seismic crews try to avoid conducting multiple surveys simultaneously in a same area, so the source interference problem normally does not occur, and suppression of coherent noise from another active source has rarely been discussed and proposed before. This paper presents a dataset in which part of the records are contaminated by shot noise from another seismic vessel, and proposes a hybrid approach to suppress the coherent noise from that unwanted seismic source. Noise subtraction and primary signal preservation within different data properties are considered to begin the noise suppression. Based on different noise characteristics from various source directions and wave propagation paths, coherence noise can be separated from primary signals in frequency-wave number (F-K), frequency-time (F-T) and intercept time-slowness (tau-p) domains, respectively. This hybrid coherent noise suppression approach involves applying three different filters, F-K, F-T and tau-p, to the contaminated dataset. Our results show that most of the coherent noise generated by another seismic source could be suppressed, and seismic images could be substantially improved.

  8. Thin crust in the southern Nansen Basin imaged with multi-channel seismic data

    NASA Astrophysics Data System (ADS)

    Lutz, Rüdiger; Franke, Dieter; Berglar, Kai; Heyde, Ingo; Klitzke, Peter

    2017-04-01

    We study the oldest crust of the Nansen Basin formed at the slow spreading Gakkel Ridge in the Arctic Ocean and its transition to the continental northern Barents Sea margin. Our data cover the transition from the continental northern Barents Sea margin across a narrow continental margin into the oceanic Nansen Basin. Across the margin, the seafloor drops down more than 2 km over a distance of about 10 km accompanied by two large normal faults, clearly imaged in seismic data. We interpret this as the expression of a transform margin. The crust in the southern Nansen Basin does not resemble the style of typical oceanic crust and the continent ocean boundary might be situated several tens of kilometers north of the transform margin as defined by deeply-reaching normal faults. Farther to the north, normal faults separate individual rotated blocks. Towards Gakkel Ridge faults bend and form listric normal faults which root in an undulating reflector at a depth of 0.3-1.3 s (TWT) below the top of the acoustic basement. Magnetic anomalies are well developed in the Nansen Basin and interpreted by various authors to at least chron C24. An analysis of these anomalies show, that spreading velocities at the Gakkel Ridge changed over time from slow to ultra-slow spreading at present. Our reflection seismic data image 170 km of the Nansen Basin and reach magnetic anomaly C22 at the northernmost part, thus covering a time span of about 5 Myr. In this contribution, we discuss the nature of the crust and the transition from continental rifting to slow seafloor spreading. Potentially, the continent-ocean transition is formed by blocks of extended continental crust. Farther to the north, exhumed mantle-derived rocks may form the blocks.

  9. THREE-DIMENSIONAL INNERVATION ZONE IMAGING FROM MULTI-CHANNEL SURFACE EMG RECORDINGS

    PubMed Central

    LIU, YANG; NING, YONG; LI, SHENG; ZHOU, PING; RYMER, WILLIAM Z.; ZHANG, YINGCHUN

    2017-01-01

    There is an unmet need to accurately identify the locations of innervation zones (IZs) of spastic muscles, so as to guide botulinum toxin (BTX) injections for the best clinical outcome. A novel 3-dimensional IZ imaging (3DIZI) approach was developed by combining the bioelectrical source imaging and surface electromyogram (EMG) decomposition methods to image the 3D distribution of IZs in the target muscles. Surface IZ locations of motor units (MUs), identified from the bipolar map of their motor unit action potentials (MUAPs) were employed as a prior knowledge in the 3DIZI approach to improve its imaging accuracy. The performance of the 3DIZI approach was first optimized and evaluated via a series of designed computer simulations, and then validated with the intramuscular EMG data, together with simultaneously recorded 128-channel surface EMG data from the biceps of two subjects. Both simulation and experimental validation results demonstrate the high performance of the 3DIZI approach in accurately reconstructing the distributions of IZs and the dynamic propagation of internal muscle activities in the biceps from high-density surface EMG recordings. PMID:26160432

  10. Three-Dimensional Innervation Zone Imaging from Multi-Channel Surface EMG Recordings.

    PubMed

    Liu, Yang; Ning, Yong; Li, Sheng; Zhou, Ping; Rymer, William Z; Zhang, Yingchun

    2015-09-01

    There is an unmet need to accurately identify the locations of innervation zones (IZs) of spastic muscles, so as to guide botulinum toxin (BTX) injections for the best clinical outcome. A novel 3D IZ imaging (3DIZI) approach was developed by combining the bioelectrical source imaging and surface electromyogram (EMG) decomposition methods to image the 3D distribution of IZs in the target muscles. Surface IZ locations of motor units (MUs), identified from the bipolar map of their MU action potentials (MUAPs) were employed as a prior knowledge in the 3DIZI approach to improve its imaging accuracy. The performance of the 3DIZI approach was first optimized and evaluated via a series of designed computer simulations, and then validated with the intramuscular EMG data, together with simultaneously recorded 128-channel surface EMG data from the biceps of two subjects. Both simulation and experimental validation results demonstrate the high performance of the 3DIZI approach in accurately reconstructing the distributions of IZs and the dynamic propagation of internal muscle activities in the biceps from high-density surface EMG recordings.

  11. 3kk: the Optical-NIR Multi-Channel Nasmyth Imager for the Wendelstein Fraunhofer Telescope

    NASA Astrophysics Data System (ADS)

    Lang-Bardl, Florian; Hodapp, Klaus; Jacobson, Shane; Bender, Ralf; Gössl, Claus; Fabricius, Maximilian; Grupp, Frank; Hopp, Ulrich; Mitsch, Wolfgang

    2010-07-01

    The Ludwig-Maximilians-Universität München operates an astrophysical observatory on the summit of Mt. Wendelstein1 which will be equipped with a modern 2m-class, robotic telescope.2 One Nasmyth port of the new Fraunhofer telescope is designed to deliver the excellent (< 0.8" median) seeing of the site [1, Fig. 1] for a smaller FoV of 60 arcmin2 without any corrector optics at optical and NIR wavebands. Thus, it will be optimized for fast multi-wavelength follow-up observations of targets of opportunities (e.g. Gamma-Ray-bursts) or efficient photometric redshift determinations of huge numbers of galaxy clusters identified in optical (PanSTARRS), SZ (Planck) or X-ray (eROSITA) surveys. We present the design of a compact 3 channel camera which serves these science requirements, built partly from commercially available Fairchild-2k optical CCD3 cameras (Apogee), coupled with small Bonn Shutters,4 and mounted on commercial high precision linear stages for differential focusing. A specially designed beam-splitter system maintains the high optical quality. The NIR camera is built in cooperation with the Institute for Astronomy in Hawaii. The combined operation of this camera with two spectrographs at the same telescope port has already been presented at SPIE 2008.5

  12. Complex metrology on 3D structures using multi-channel OCD

    NASA Astrophysics Data System (ADS)

    Kagalwala, Taher; Mahendrakar, Sridhar; Vaid, Alok; Isbester, Paul K.; Cepler, Aron; Kang, Charles; Yellai, Naren; Sendelbach, Matthew; Ko, Mihael; Ilgayev, Ovadia; Katz, Yinon; Tamam, Lilach; Osherov, Ilya

    2017-03-01

    Device scaling has not only driven the use of measurements on more complex structures, in terms of geometry, materials, and tighter ground rules, but also the need to move away from non-patterned measurement sites to patterned ones. This is especially of concern for very thin film layers that have a high thickness dependence on structure geometry or wafer pattern factor. Although 2-dimensional (2D) sites are often found to be sufficient for process monitoring and control of very thin films, sometimes 3D sites are required to further simulate structures within the device. The measurement of film thicknesses only a few atoms thick on complex 3D sites, however, are very challenging. Apart from measuring thin films on 3D sites, there is also a critical need to measure parameters on 3D sites, which are weak and less sensitive for OCD (Optical Critical Dimension) metrology, with high accuracy and precision. Thus, state-ofthe-art methods are needed to address such metrology challenges. This work introduces the concept of Enhanced OCD which uses various methods to improve the sensitivity and reduce correlations for weak parameters in a complex measurement. This work also describes how more channels of information, when used correctly, can improve the precision and accuracy of weak, non-sensitive or complex parameters of interest.

  13. A floating multi-channel picoammeter for micropattern gaseous detector current monitoring

    NASA Astrophysics Data System (ADS)

    Utrobicic, A.; Kovacic, M.; Erhardt, F.; Poljak, N.; Planinic, M.

    2015-11-01

    This paper presents a concept of a multiple channel picoammeter suitable for operation at a high voltage. To ensure floating operation, 1 kHz readout rate and low battery usage, the picoammeter employs an optical fibre for data transmission. The analogue conditioning section consists of a transimpedance amplifier that is connected to a 16 bit ΣΔ ADC which is integrated into the microcontroller. Simultaneous reception of data sent from multiple picoammeter units is achieved using an FPGA device and a USB interface to the host PC. A prototype with a ± 125 nA range was constructed. The paper includes a calibration procedure of the prototype and an example of a current leakage test conducted on a 10×10 cm2 GEM foil. The resolution achieved by the prototype in a 15 min test at 0.5 nA bias was 6.5 pA FWHM.

  14. Diffractive element design for generating multi-channel structured light field

    NASA Astrophysics Data System (ADS)

    Wang, Jia-Zhou; Pang, Hui; Zhang, Man; Shi, Li-Fang; Cao, A.-Xiu; Deng, Qi-Ling; Hu, Song

    2016-10-01

    With the advantages of small structure and high efficiency, the diffractive element is widely used in the construction of a structured light 3D measurement system. But the working wavelength of diffraction element is single, and the light field generated by the diffraction element is only one channel. We make the original single channel into three channels, so as to achieve from the serial algorithm to parallel algorithm to improve the measurement speed. Based on the lattice light field and the design method of multi wavelength diffraction elements, and in the premise of ensuring the number of points, the traditional lattice points of light field are divided into three channels. These channels are regarded as the target fields, and the diffraction element for generating color structure light field is designed.

  15. Studies on Physical Properties of Snow Based on Multi Channel Microwave Radiometer

    NASA Technical Reports Server (NTRS)

    Tsuchiya, K.; Takeda, K.

    1985-01-01

    The analysis of the data observed over a snow field with a breadboard model of MSR (microwave scanning radiometer) to be installed in MOS-1 (Marine Observation Satellite-1) indicates that: (1) the influence of incident angle on brightness temperature is larger in horizontal polarization component than in vertical polarization component. The effect of incident angle depends upon the property of snow with larger value for dry snow; (2) the difference of snow surface configuration consisting of artifically made parallel ditches of 5 cm depth and 5 cm width with spacing of 10 and 30 cm respectively which are oriented normal to electrical axis do not affect brightness temperature significantly; and (3) there is high negative correlation between brightness temperature and snow depth up to the depth of 70 cm which suggests that the snow depth can be measured with a two channel microwave radiometer up to this depth.

  16. Coherent pulse detection and multi-channel coherent detection based on a single balanced homodyne receiver.

    PubMed

    Lee, Wangkuen; Izadpanah, Hoss; Delfyett, Peter J; Menendez, Ron; Etemad, Shahab

    2007-03-05

    The performance of coherent pulse detection (CPD) and multichannel coherent detection (MCCD) based on a single dual-balanced homodyne receiver was experimentally demonstrated using a gratingcoupled hybridly mode-locked semiconductor laser. Compared with direct detection, a high coherent gain of over 10 dB, as well as an SNR improvement of over 5 dB, was obtained in both detection schemes. Our experimental results have confirmed that the coherent detection processes in CPD and MCCD are nearly the same based on a square-root LO power dependence. Nevertheless, the MCCD scheme has shown an advantage in a path-length error over the CPD scheme, revealing 2~3 dB improvement in sensitivities.

  17. Design, modeling, and analysis of multi-channel demultiplexer/demodulator

    NASA Technical Reports Server (NTRS)

    Lee, David D.; Woo, K. T.

    1991-01-01

    Traditionally, satellites have performed the function of a simple repeater. Newer data distribution satellite architectures, however, require demodulation of many frequency division multiplexed uplink channels by a single demultiplexer/demodulator unit, baseband processing and routing of individual voice/data circuits, and remodulation into time division multiplexed (TDM) downlink carriers. The TRW MCDD (Multichannel Demultiplexer/Multirate Demodulator) operates on a 37.4 MHz composite input signal. Individual channel data rates are either 64 Kbps or 2.048 Mbps. The wideband demultiplexer divides the input signal into 1.44 MHz segments containing either a single 2.048 Mbps channel or thirty two 64 Kbps channels. In the latter case, the narrowband demultiplexer further divides the single 1.44 MHz wideband channel into thirty two 45 KHz narrowband channels. With this approach the time domain Fast Fourier Transformation (FFT) channelizer processing capacity is matched well to the bandwidth and number of channels to be demultiplexed. By using a multirate demodulator fewer demodulators are required while achieving greater flexibility. Each demodulator can process a wideband channel or thirty two narrowband channels. Either all wideband channels, a mixture of wideband and narrowband channels, or all narrowband channels can be demodulated. The multirate demodulator approach also has lower nonrecurring costs since only one design and development effort is needed. TRW has developed a proof of concept (POC) model which fully demonstrates the signal processing fuctions of MCDD. It is capable of processing either three 2.048 Mbps channels or two 2.048 Mbps channels and thirty two 64 Kbps channels. An overview of important MCDD system engineering issues is presented as well as discussion on some of the Block Oriented System Simulation analyses performed for design verification and selection of operational parameters of the POC model. Systems engineering analysis of the POC

  18. Functional connectivity among multi-channel EEGs when working memory load reaches the capacity.

    PubMed

    Zhang, Dan; Zhao, Huipo; Bai, Wenwen; Tian, Xin

    2016-01-15

    Evidence from behavioral studies has suggested a capacity existed in working memory. As the concept of functional connectivity has been introduced into neuroscience research in the recent years, the aim of this study is to investigate the functional connectivity in the brain when working memory load reaches the capacity. 32-channel electroencephalographs (EEGs) were recorded for 16 healthy subjects, while they performed a visual working memory task with load 1-6. Individual working memory capacity was calculated according to behavioral results. Short-time Fourier transform was used to determine the principal frequency band (theta band) related to working memory. The functional connectivity among EEGs was measured by the directed transform function (DTF) via spectral Granger causal analysis. The capacity was 4 calculated from the behavioral results. The power was focused in th