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Sample records for multimodal em cirurgia

  1. Multimodality Prediction of Chaotic Time Series with Sparse Hard-Cut EM Learning of the Gaussian Process Mixture Model

    NASA Astrophysics Data System (ADS)

    Zhou, Ya-Tong; Fan, Yu; Chen, Zi-Yi; Sun, Jian-Cheng

    2017-05-01

    The contribution of this work is twofold: (1) a multimodality prediction method of chaotic time series with the Gaussian process mixture (GPM) model is proposed, which employs a divide and conquer strategy. It automatically divides the chaotic time series into multiple modalities with different extrinsic patterns and intrinsic characteristics, and thus can more precisely fit the chaotic time series. (2) An effective sparse hard-cut expectation maximization (SHC-EM) learning algorithm for the GPM model is proposed to improve the prediction performance. SHC-EM replaces a large learning sample set with fewer pseudo inputs, accelerating model learning based on these pseudo inputs. Experiments on Lorenz and Chua time series demonstrate that the proposed method yields not only accurate multimodality prediction, but also the prediction confidence interval. SHC-EM outperforms the traditional variational learning in terms of both prediction accuracy and speed. In addition, SHC-EM is more robust and insusceptible to noise than variational learning. Supported by the National Natural Science Foundation of China under Grant No 60972106, the China Postdoctoral Science Foundation under Grant No 2014M561053, the Humanity and Social Science Foundation of Ministry of Education of China under Grant No 15YJA630108, and the Hebei Province Natural Science Foundation under Grant No E2016202341.

  2. The Intersection of Multimodality and Critical Perspective: Multimodality as Subversion

    ERIC Educational Resources Information Center

    Huang, Shin-ying

    2015-01-01

    This study explores the relevance of multimodality to critical media literacy. It is based on the understanding that communication is intrinsically multimodal and multimodal communication is inherently social and ideological. By analysing two English-language learners' multimodal ensembles, the study reports on how multimodality contributes to a…

  3. The Intersection of Multimodality and Critical Perspective: Multimodality as Subversion

    ERIC Educational Resources Information Center

    Huang, Shin-ying

    2015-01-01

    This study explores the relevance of multimodality to critical media literacy. It is based on the understanding that communication is intrinsically multimodal and multimodal communication is inherently social and ideological. By analysing two English-language learners' multimodal ensembles, the study reports on how multimodality contributes to a…

  4. Multimodal Learning Clubs

    ERIC Educational Resources Information Center

    Casey, Heather

    2012-01-01

    Multimodal learning clubs link principles of motivation and engagement with 21st century technological tools and texts to support content area learning. The author describes how a sixth grade health teacher and his class incorporated multimodal learning clubs into a unit of study on human body systems. The students worked collaboratively online…

  5. Multimodal Learning Clubs

    ERIC Educational Resources Information Center

    Casey, Heather

    2012-01-01

    Multimodal learning clubs link principles of motivation and engagement with 21st century technological tools and texts to support content area learning. The author describes how a sixth grade health teacher and his class incorporated multimodal learning clubs into a unit of study on human body systems. The students worked collaboratively online…

  6. Multimode Directional Coupler

    NASA Technical Reports Server (NTRS)

    Simons, Rainee N. (Inventor); Wintucky, Edwin G. (Inventor)

    2016-01-01

    A multimode directional coupler is provided. In some embodiments, the multimode directional coupler is configured to receive a primary signal and a secondary signal at a first port of a primary waveguide. The primary signal is configured to propagate through the primary waveguide and be outputted at a second port of the primary waveguide. The multimode directional coupler also includes a secondary waveguide configured to couple the secondary signal from the primary waveguide with no coupling of the primary signal into the secondary waveguide. The secondary signal is configured to propagate through the secondary waveguide and be outputted from a port of the secondary waveguide.

  7. Multispectral analysis of multimodal images.

    PubMed

    Kvinnsland, Yngve; Brekke, Njål; Taxt, Torfinn M; Grüner, Renate

    2009-01-01

    An increasing number of multimodal images represent a valuable increase in available image information, but at the same time it complicates the extraction of diagnostic information across the images. Multispectral analysis (MSA) has the potential to simplify this problem substantially as unlimited number of images can be combined, and tissue properties across the images can be extracted automatically. We have developed a software solution for MSA containing two algorithms for unsupervised classification, an EM-algorithm finding multinormal class descriptions and the k-means clustering algorithm, and two for supervised classification, a Bayesian classifier using multinormal class descriptions and a kNN-algorithm. The software has an efficient user interface for the creation and manipulation of class descriptions, and it has proper tools for displaying the results. The software has been tested on different sets of images. One application is to segment cross-sectional images of brain tissue (T1- and T2-weighted MR images) into its main normal tissues and brain tumors. Another interesting set of images are the perfusion maps and diffusion maps, derived images from raw MR images. The software returns segmentations that seem to be sensible. The MSA software appears to be a valuable tool for image analysis with multimodal images at hand. It readily gives a segmentation of image volumes that visually seems to be sensible. However, to really learn how to use MSA, it will be necessary to gain more insight into what tissues the different segments contain, and the upcoming work will therefore be focused on examining the tissues through for example histological sections.

  8. Multimodal sequence learning.

    PubMed

    Kemény, Ferenc; Meier, Beat

    2016-02-01

    While sequence learning research models complex phenomena, previous studies have mostly focused on unimodal sequences. The goal of the current experiment is to put implicit sequence learning into a multimodal context: to test whether it can operate across different modalities. We used the Task Sequence Learning paradigm to test whether sequence learning varies across modalities, and whether participants are able to learn multimodal sequences. Our results show that implicit sequence learning is very similar regardless of the source modality. However, the presence of correlated task and response sequences was required for learning to take place. The experiment provides new evidence for implicit sequence learning of abstract conceptual representations. In general, the results suggest that correlated sequences are necessary for implicit sequence learning to occur. Moreover, they show that elements from different modalities can be automatically integrated into one unitary multimodal sequence.

  9. Programmable multimode quantum networks

    PubMed Central

    Armstrong, Seiji; Morizur, Jean-François; Janousek, Jiri; Hage, Boris; Treps, Nicolas; Lam, Ping Koy; Bachor, Hans-A.

    2012-01-01

    Entanglement between large numbers of quantum modes is the quintessential resource for future technologies such as the quantum internet. Conventionally, the generation of multimode entanglement in optics requires complex layouts of beamsplitters and phase shifters in order to transform the input modes into entangled modes. Here we report the highly versatile and efficient generation of various multimode entangled states with the ability to switch between different linear optics networks in real time. By defining our modes to be combinations of different spatial regions of one beam, we may use just one pair of multi-pixel detectors in order to measure multiple entangled modes. We programme virtual networks that are fully equivalent to the physical linear optics networks they are emulating. We present results for N=2 up to N=8 entangled modes here, including N=2, 3, 4 cluster states. Our approach introduces the highly sought after attributes of flexibility and scalability to multimode entanglement. PMID:22929783

  10. Multimodality imaging techniques.

    PubMed

    Martí-Bonmatí, Luis; Sopena, Ramón; Bartumeus, Paula; Sopena, Pablo

    2010-01-01

    In multimodality imaging, the need to combine morphofunctional information can be approached by either acquiring images at different times (asynchronous), and fused them through digital image manipulation techniques or simultaneously acquiring images (synchronous) and merging them automatically. The asynchronous post-processing solution presents various constraints, mainly conditioned by the different positioning of the patient in the two scans acquired at different times in separated machines. The best solution to achieve consistency in time and space is obtained by the synchronous image acquisition. There are many multimodal technologies in molecular imaging. In this review we will focus on those multimodality image techniques more commonly used in the field of diagnostic imaging (SPECT-CT, PET-CT) and new developments (as PET-MR). The technological innovations and development of new tracers and smart probes are the main key points that will condition multimodality image and diagnostic imaging professionals' future. Although SPECT-CT and PET-CT are standard in most clinical scenarios, MR imaging has some advantages, providing excellent soft-tissue contrast and multidimensional functional, structural and morphological information. The next frontier is to develop efficient detectors and electronics systems capable of detecting two modality signals at the same time. Not only PET-MR but also MR-US or optic-PET will be introduced in clinical scenarios. Even more, MR diffusion-weighted, pharmacokinetic imaging, spectroscopy or functional BOLD imaging will merge with PET tracers to further increase molecular imaging as a relevant medical discipline. Multimodality imaging techniques will play a leading role in relevant clinical applications. The development of new diagnostic imaging research areas, mainly in the field of oncology, cardiology and neuropsychiatry, will impact the way medicine is performed today. Both clinical and experimental multimodality studies, in

  11. Multimodal Information Exploration.

    ERIC Educational Resources Information Center

    Stock, Oliviero; Zancanaro, Massimo; Strapparava, Carlo

    1997-01-01

    Discussion of information exploration and software design in computer-based educational systems focuses on the integration of hypermedia and natural language dialog. AlFRESCO is described, an interactive natural language-centered multimodal system that was developed for users interested in frescoes and paintings. (LRW)

  12. Generating Multimodal References

    ERIC Educational Resources Information Center

    van der Sluis, Ielka; Krahmer, Emiel

    2007-01-01

    This article presents a new computational model for the generation of multimodal referring expressions (REs), based on observations in human communication. The algorithm is an extension of the graph-based algorithm proposed by Krahmer, van Erk, and Verleg (2003) and makes use of a so-called Flashlight Model for pointing. The Flashlight Model…

  13. Generating Multimodal References

    ERIC Educational Resources Information Center

    van der Sluis, Ielka; Krahmer, Emiel

    2007-01-01

    This article presents a new computational model for the generation of multimodal referring expressions (REs), based on observations in human communication. The algorithm is an extension of the graph-based algorithm proposed by Krahmer, van Erk, and Verleg (2003) and makes use of a so-called Flashlight Model for pointing. The Flashlight Model…

  14. Multimode optical fiber

    DOEpatents

    Bigot-Astruc, Marianne; Molin, Denis; Sillard, Pierre

    2014-11-04

    A depressed graded-index multimode optical fiber includes a central core, an inner depressed cladding, a depressed trench, an outer depressed cladding, and an outer cladding. The central core has an alpha-index profile. The depressed claddings limit the impact of leaky modes on optical-fiber performance characteristics (e.g., bandwidth, core size, and/or numerical aperture).

  15. Multimodal eye recognition

    NASA Astrophysics Data System (ADS)

    Zhou, Zhi; Du, Yingzi; Thomas, N. L.; Delp, Edward J., III

    2010-04-01

    Multimodal biometrics use more than one means of biometric identification to achieve higher recognition accuracy, since sometimes a unimodal biometric is not good enough used to do identification and classification. In this paper, we proposed a multimodal eye recognition system, which can obtain both iris and sclera patterns from one color eye image. Gabor filter and 1-D Log-Gabor filter algorithms have been applied as the iris recognition algorithms. In sclera recognition, we introduced automatic sclera segmentation, sclera pattern enhancement, sclera pattern template generation, and sclera pattern matching. We applied kernelbased matching score fusion to improve the performance of the eye recognition system. The experimental results show that the proposed eye recognition method can achieve better performance compared to unimodal biometric identification, and the accuracy of our proposed kernel-based matching score fusion method is higher than two classic linear matching score fusion methods: Principal Component Analysis (PCA) and Linear Discriminant Analysis (LDA).

  16. Multimodal Nonlinear Optical Microscopy

    PubMed Central

    Yue, Shuhua; Slipchenko, Mikhail N.; Cheng, Ji-Xin

    2013-01-01

    Because each nonlinear optical (NLO) imaging modality is sensitive to specific molecules or structures, multimodal NLO imaging capitalizes the potential of NLO microscopy for studies of complex biological tissues. The coupling of multiphoton fluorescence, second harmonic generation, and coherent anti-Stokes Raman scattering (CARS) has allowed investigation of a broad range of biological questions concerning lipid metabolism, cancer development, cardiovascular disease, and skin biology. Moreover, recent research shows the great potential of using CARS microscope as a platform to develop more advanced NLO modalities such as electronic-resonance-enhanced four-wave mixing, stimulated Raman scattering, and pump-probe microscopy. This article reviews the various approaches developed for realization of multimodal NLO imaging as well as developments of new NLO modalities on a CARS microscope. Applications to various aspects of biological and biomedical research are discussed. PMID:24353747

  17. A multimodal parallel architecture: A cognitive framework for multimodal interactions.

    PubMed

    Cohn, Neil

    2016-01-01

    Human communication is naturally multimodal, and substantial focus has examined the semantic correspondences in speech-gesture and text-image relationships. However, visual narratives, like those in comics, provide an interesting challenge to multimodal communication because the words and/or images can guide the overall meaning, and both modalities can appear in complicated "grammatical" sequences: sentences use a syntactic structure and sequential images use a narrative structure. These dual structures create complexity beyond those typically addressed by theories of multimodality where only a single form uses combinatorial structure, and also poses challenges for models of the linguistic system that focus on single modalities. This paper outlines a broad theoretical framework for multimodal interactions by expanding on Jackendoff's (2002) parallel architecture for language. Multimodal interactions are characterized in terms of their component cognitive structures: whether a particular modality (verbal, bodily, visual) is present, whether it uses a grammatical structure (syntax, narrative), and whether it "dominates" the semantics of the overall expression. Altogether, this approach integrates multimodal interactions into an existing framework of language and cognition, and characterizes interactions between varying complexity in the verbal, bodily, and graphic domains. The resulting theoretical model presents an expanded consideration of the boundaries of the "linguistic" system and its involvement in multimodal interactions, with a framework that can benefit research on corpus analyses, experimentation, and the educational benefits of multimodality. Copyright © 2015.

  18. Multimodal Analysis for Critical Thinking

    ERIC Educational Resources Information Center

    O'Halloran, Kay L.; Tan, Sabine; E., Marissa K. L.

    2017-01-01

    This paper proposes a pedagogical approach for teaching and learning critical thinking through multimodal analysis--that is, "multimodal analysis for critical thinking". The approach builds on the conviction that students require competencies that move beyond traditional notions of literacy to meet the changing demands posed by media and…

  19. Multimodal Biomedical Imaging Systems

    NASA Astrophysics Data System (ADS)

    Liang, Rongguang

    Optical imaging technologies can provide real-time images of tissues in vivo and have the potential to reveal biochemical and/or molecular information; therefore, they can significantly improve identification of malignancy at early stages. The ability to obtain tissue architectural morphology and molecular information in vivo, without the need for tissue excision, offers advancement in disease diagnostics and therapy. Multimodal imaging systems combining multiple imaging modalities for complementary tissue information offer a number of advantages compared with a single imaging modality and improve the diagnosis and treatment of diseases using distinct imaging techniques.

  20. Multimodality image display station

    NASA Astrophysics Data System (ADS)

    Myers, H. Joseph

    1990-07-01

    The Multi-modality Image Display Station (MIDS) is designed for the use of physicians outside of the radiology department. Connected to a local area network or a host computer, it provides speedy access to digitized radiology images and written diagnostics needed by attending and consulting physicians near the patient bedside. Emphasis has been placed on low cost, high performance and ease of use. The work is being done as a joint study with the University of Texas Southwestern Medical Center at Dallas, and as part of a joint development effort with the Mayo Clinic. MIDS is a prototype, and should not be assumed to be an IBM product.

  1. Multimodality of Learning Through Anchored Instruction

    ERIC Educational Resources Information Center

    Love, Mary Susan

    2004-01-01

    Multimodality of learning results from the intertextual relationship between multimodal design and other meaning-making modes. Meaning making is becoming more multimodal because language is continually reshaped by new forms of communication media. This article examines anchored instruction from a multimodal perspective. The first section includes…

  2. Learning multimodal latent attributes.

    PubMed

    Fu, Yanwei; Hospedales, Timothy M; Xiang, Tao; Gong, Shaogang

    2014-02-01

    The rapid development of social media sharing has created a huge demand for automatic media classification and annotation techniques. Attribute learning has emerged as a promising paradigm for bridging the semantic gap and addressing data sparsity via transferring attribute knowledge in object recognition and relatively simple action classification. In this paper, we address the task of attribute learning for understanding multimedia data with sparse and incomplete labels. In particular, we focus on videos of social group activities, which are particularly challenging and topical examples of this task because of their multimodal content and complex and unstructured nature relative to the density of annotations. To solve this problem, we 1) introduce a concept of semilatent attribute space, expressing user-defined and latent attributes in a unified framework, and 2) propose a novel scalable probabilistic topic model for learning multimodal semilatent attributes, which dramatically reduces requirements for an exhaustive accurate attribute ontology and expensive annotation effort. We show that our framework is able to exploit latent attributes to outperform contemporary approaches for addressing a variety of realistic multimedia sparse data learning tasks including: multitask learning, learning with label noise, N-shot transfer learning, and importantly zero-shot learning.

  3. [Multimodal pain therapy].

    PubMed

    Böger, A

    2014-06-01

    Chronic pain has both high prevalence and a significant economic impact in Germany. The most common chronic pain types are low back pain and headache. On the one hand, the management of chronic pain patients is incomplete, yet it is often overtreated in orthopaedic surgical settings with interventional procedures. The reason for this is the structure of outpatient management and the way it is paid for in Germany. Pain management of patients with private insurance cover is no better because of "doctor shopping". Medical guidelines could be of some help in improving the situation, but they are widely unknown, and have still to demonstrate whether they have any impact on GP treatment pathways. The "gold standard" multimodal pain therapy shows significant improvement in many studies compared to monomodal therapy regimes and interventional regimes, but is too rarely recommended by the patients' physicians, whether GPs or specialists. Because of the huge number of institutions nowadays that, for the sake of form, offer such multimodal therapies, these need to be differentiated in terms of their structural and process quality. A first step is the "k edoq" project. It is essential to improve knowledge of the principles of modern pain management. This includes better networking and communication between doctors, physiotherapists and psychologists, and at the grassroots level, providing the public with more detailed and better information.

  4. Multimode silicon nanowire transistors.

    PubMed

    Glassner, Sebastian; Zeiner, Clemens; Periwal, Priyanka; Baron, Thierry; Bertagnolli, Emmerich; Lugstein, Alois

    2014-11-12

    The combined capabilities of both a nonplanar design and nonconventional carrier injection mechanisms are subject to recent scientific investigations to overcome the limitations of silicon metal oxide semiconductor field effect transistors. In this Letter, we present a multimode field effect transistors device using silicon nanowires that feature an axial n-type/intrinsic doping junction. A heterostructural device design is achieved by employing a self-aligned nickel-silicide source contact. The polymorph operation of the dual-gate device enabling the configuration of one p- and two n-type transistor modes is demonstrated. Not only the type but also the carrier injection mode can be altered by appropriate biasing of the two gate terminals or by inverting the drain bias. With a combined band-to-band and Schottky tunneling mechanism, in p-type mode a subthreshold swing as low as 143 mV/dec and an ON/OFF ratio of up to 10(4) is found. As the device operates in forward bias, a nonconventional tunneling transistor is realized, enabling an effective suppression of ambipolarity. Depending on the drain bias, two different n-type modes are distinguishable. The carrier injection is dominated by thermionic emission in forward bias with a maximum ON/OFF ratio of up to 10(7) whereas in reverse bias a Schottky tunneling mechanism dominates the carrier transport.

  5. Multimode Silicon Nanowire Transistors

    PubMed Central

    2014-01-01

    The combined capabilities of both a nonplanar design and nonconventional carrier injection mechanisms are subject to recent scientific investigations to overcome the limitations of silicon metal oxide semiconductor field effect transistors. In this Letter, we present a multimode field effect transistors device using silicon nanowires that feature an axial n-type/intrinsic doping junction. A heterostructural device design is achieved by employing a self-aligned nickel-silicide source contact. The polymorph operation of the dual-gate device enabling the configuration of one p- and two n-type transistor modes is demonstrated. Not only the type but also the carrier injection mode can be altered by appropriate biasing of the two gate terminals or by inverting the drain bias. With a combined band-to-band and Schottky tunneling mechanism, in p-type mode a subthreshold swing as low as 143 mV/dec and an ON/OFF ratio of up to 104 is found. As the device operates in forward bias, a nonconventional tunneling transistor is realized, enabling an effective suppression of ambipolarity. Depending on the drain bias, two different n-type modes are distinguishable. The carrier injection is dominated by thermionic emission in forward bias with a maximum ON/OFF ratio of up to 107 whereas in reverse bias a Schottky tunneling mechanism dominates the carrier transport. PMID:25303290

  6. Vector-Resonance-Multimode Instability

    NASA Astrophysics Data System (ADS)

    Sergeyev, S. V.; Kbashi, H.; Tarasov, N.; Loiko, Yu.; Kolpakov, S. A.

    2017-01-01

    The modulation and multimode instabilities are the main mechanisms which drive spontaneous spatial and temporal pattern formation in a vast number of nonlinear systems ranging from biology to laser physics. Using an Er-doped fiber laser as a test bed, here for the first time we demonstrate both experimentally and theoretically a new type of a low-threshold vector-resonance-multimode instability which inherits features of multimode and modulation instabilities. The same as for the multimode instability, a large number of longitudinal modes can be excited without mode synchronization. To enable modulation instability, we modulate the state of polarization of the lasing signal with the period of the beat length by an adjustment of the in-cavity birefringence and the state of polarization of the pump wave. As a result, we show the regime's tunability from complex oscillatory to periodic with longitudinal mode synchronization in the case of resonance matching between the beat and cavity lengths. Apart from the interest in laser physics for unlocking the tunability and stability of dynamic regimes, the proposed mechanism of the vector-resonance-multimode instability can be of fundamental interest for the nonlinear dynamics of various distributed systems.

  7. Multimodal Hip Hop Productions as Media Literacies

    ERIC Educational Resources Information Center

    Turner, K. C. Nat

    2012-01-01

    This study draws on ethnographic data from a year-long multimodal media production (MMP) course and the experience of an African American female adolescent who used the production of multimodal Hip Hop texts to express her creativity and growing socially conscious view of the world. The study demonstrates how students made meaning multimodally and…

  8. Locating the Semiotic Power of Multimodality

    ERIC Educational Resources Information Center

    Hull, Glynda A.; Nelson, Mark Evan

    2005-01-01

    This article reports research that attempts to characterize what is powerful about digital multimodal texts. Building from recent theoretical work on understanding the workings and implications of multimodal communication, the authors call for a continuing empirical investigation into the roles that digital multimodal texts play in real-world…

  9. Locating the Semiotic Power of Multimodality

    ERIC Educational Resources Information Center

    Hull, Glynda A.; Nelson, Mark Evan

    2005-01-01

    This article reports research that attempts to characterize what is powerful about digital multimodal texts. Building from recent theoretical work on understanding the workings and implications of multimodal communication, the authors call for a continuing empirical investigation into the roles that digital multimodal texts play in real-world…

  10. Skill training in multimodal virtual environments.

    PubMed

    Gopher, Daniel

    2012-01-01

    Multimodal, immersive, virtual reality (VR) techniques open new perspectives for perceptual-motor skill trainers. They also introduce new risks and dangers. This paper describes the benefits and pitfalls of multimodal training and the cognitive building blocks of a multimodal, VR training simulators.

  11. Multimodal Hip Hop Productions as Media Literacies

    ERIC Educational Resources Information Center

    Turner, K. C. Nat

    2012-01-01

    This study draws on ethnographic data from a year-long multimodal media production (MMP) course and the experience of an African American female adolescent who used the production of multimodal Hip Hop texts to express her creativity and growing socially conscious view of the world. The study demonstrates how students made meaning multimodally and…

  12. Developing Multimodal Academic Literacies among College Freshmen

    ERIC Educational Resources Information Center

    Jacobs, Gloria E.

    2012-01-01

    In this article, the author draws on a semester long freshmen learning community in which multimodal texts were used as primary texts along with traditional texts to support students' academic literacy skills. Analysis shows that a multimodal text created by students contain elements of academic literacies and qualities of multimodal texts. An…

  13. Multimodal Friction Ignition Tester

    NASA Technical Reports Server (NTRS)

    Davis, Eddie; Howard, Bill; Herald, Stephen

    2009-01-01

    The multimodal friction ignition tester (MFIT) is a testbed for experiments on the thermal and mechanical effects of friction on material specimens in pressurized, oxygen-rich atmospheres. In simplest terms, a test involves recording sensory data while rubbing two specimens against each other at a controlled normal force, with either a random stroke or a sinusoidal stroke having controlled amplitude and frequency. The term multimodal in the full name of the apparatus refers to a capability for imposing any combination of widely ranging values of the atmospheric pressure, atmospheric oxygen content, stroke length, stroke frequency, and normal force. The MFIT was designed especially for studying the tendency toward heating and combustion of nonmetallic composite materials and the fretting of metals subjected to dynamic (vibrational) friction forces in the presence of liquid oxygen or pressurized gaseous oxygen test conditions approximating conditions expected to be encountered in proposed composite material oxygen tanks aboard aircraft and spacecraft in flight. The MFIT includes a stainless-steel pressure vessel capable of retaining the required test atmosphere. Mounted atop the vessel is a pneumatic cylinder containing a piston for exerting the specified normal force between the two specimens. Through a shaft seal, the piston shaft extends downward into the vessel. One of the specimens is mounted on a block, denoted the pressure block, at the lower end of the piston shaft. This specimen is pressed down against the other specimen, which is mounted in a recess in another block, denoted the slip block, that can be moved horizontally but not vertically. The slip block is driven in reciprocating horizontal motion by an electrodynamic vibration exciter outside the pressure vessel. The armature of the electrodynamic exciter is connected to the slip block via a horizontal shaft that extends into the pressure vessel via a second shaft seal. The reciprocating horizontal

  14. Multimodal pain management and arthrofibrosis.

    PubMed

    Lavernia, Carlos; Cardona, Diego; Rossi, Mark D; Lee, David

    2008-09-01

    Pain control after arthroplasty has been a key concern for orthopedic surgeons. After total knee arthroplasty (TKA), a small group of patients developed a painful joint with suboptimal range of motion. Manipulation under anesthesia increases flexion and extension while decreasing pain in most cases. The objective of the present investigation is to asses the effect of a multimodal pain management protocol on arthrofibrosis in primary TKAs. A cohort of 1136 patients who underwent primary TKA was selected. Patients were divided into 2 groups: group A had 778 procedures performed using a traditional approach to pain control; group B included 358 procedures that received multimodal pain management. Group A had an incidence of manipulation of 4.75% (37/778). Of 357 patients, 8 required manipulation in group B, which is an incidence of 2.24%. We recommend that orthopedic surgeons consider using a multimodal pain management protocol for TKA.

  15. Multimodal Neuroelectric Interface Development

    NASA Technical Reports Server (NTRS)

    Trejo, Leonard J.; Wheeler, Kevin R.; Jorgensen, Charles C.; Totah, Joseph (Technical Monitor)

    2001-01-01

    This project aims to improve performance of NASA missions by developing multimodal neuroelectric technologies for augmented human-system interaction. Neuroelectric technologies will add completely new modes of interaction that operate in parallel with keyboards, speech, or other manual controls, thereby increasing the bandwidth of human-system interaction. We recently demonstrated the feasibility of real-time electromyographic (EMG) pattern recognition for a direct neuroelectric human-computer interface. We recorded EMG signals from an elastic sleeve with dry electrodes, while a human subject performed a range of discrete gestures. A machine-teaming algorithm was trained to recognize the EMG patterns associated with the gestures and map them to control signals. Successful applications now include piloting two Class 4 aircraft simulations (F-15 and 757) and entering data with a "virtual" numeric keyboard. Current research focuses on on-line adaptation of EMG sensing and processing and recognition of continuous gestures. We are also extending this on-line pattern recognition methodology to electroencephalographic (EEG) signals. This will allow us to bypass muscle activity and draw control signals directly from the human brain. Our system can reliably detect P-rhythm (a periodic EEG signal from motor cortex in the 10 Hz range) with a lightweight headset containing saline-soaked sponge electrodes. The data show that EEG p-rhythm can be modulated by real and imaginary motions. Current research focuses on using biofeedback to train of human subjects to modulate EEG rhythms on demand, and to examine interactions of EEG-based control with EMG-based and manual control. Viewgraphs on these neuroelectric technologies are also included.

  16. Large area TES spiderweb bolometer for multi-mode cavity microwave detect

    NASA Astrophysics Data System (ADS)

    Biasotti, M.; Bagliani, D.; Ceriale, V.; Corsini, D.; De Bernardis, P.; Gatti, F.; Gualtieri, R.; Lamagna, L.; Masi, S.; Pizzigoni, G.; Schillaci, A.

    2014-07-01

    Large area spiderweb bolometers of 8 mm diameter and a mesh size of 250 μm are fabricated in order to couple with approximately the first 20 modes of a multimode EM cavity at about 140 GHz. The sensor is a Ti/Au/Ti 3 layer TES with Tc tuned in the 330-380 mK and 2 mK transition width. We describe the detector design and the fabrication process, early TES electro-thermal measurements. We also report optical coupling measurement and show the multimode coupling.

  17. A Learning Algorithm for Multimodal Grammar Inference.

    PubMed

    D'Ulizia, A; Ferri, F; Grifoni, P

    2011-12-01

    The high costs of development and maintenance of multimodal grammars in integrating and understanding input in multimodal interfaces lead to the investigation of novel algorithmic solutions in automating grammar generation and in updating processes. Many algorithms for context-free grammar inference have been developed in the natural language processing literature. An extension of these algorithms toward the inference of multimodal grammars is necessary for multimodal input processing. In this paper, we propose a novel grammar inference mechanism that allows us to learn a multimodal grammar from its positive samples of multimodal sentences. The algorithm first generates the multimodal grammar that is able to parse the positive samples of sentences and, afterward, makes use of two learning operators and the minimum description length metrics in improving the grammar description and in avoiding the over-generalization problem. The experimental results highlight the acceptable performances of the algorithm proposed in this paper since it has a very high probability of parsing valid sentences.

  18. Multimodal imaging of ischemic wounds

    NASA Astrophysics Data System (ADS)

    Zhang, Shiwu; Gnyawali, Surya; Huang, Jiwei; Liu, Peng; Gordillo, Gayle; Sen, Chandan K.; Xu, Ronald

    2012-12-01

    The wound healing process involves the reparative phases of inflammation, proliferation, and remodeling. Interrupting any of these phases may result in chronically unhealed wounds, amputation, or even patient death. Quantitative assessment of wound tissue ischemia, perfusion, and inflammation provides critical information for appropriate detection, staging, and treatment of chronic wounds. However, no method is available for noninvasive, simultaneous, and quantitative imaging of these tissue parameters. We integrated hyperspectral, laser speckle, and thermographic imaging modalities into a single setup for multimodal assessment of tissue oxygenation, perfusion, and inflammation characteristics. Advanced algorithms were developed for accurate reconstruction of wound oxygenation and appropriate co-registration between different imaging modalities. The multimodal wound imaging system was validated by an ongoing clinical trials approved by OSU IRB. In the clinical trial, a wound of 3mm in diameter was introduced on a healthy subject's lower extremity and the healing process was serially monitored by the multimodal imaging setup. Our experiments demonstrated the clinical usability of multimodal wound imaging.

  19. Multi-Modality Phantom Development

    SciTech Connect

    Huber, Jennifer S.; Peng, Qiyu; Moses, William W.

    2009-03-20

    Multi-modality imaging has an increasing role in the diagnosis and treatment of a large number of diseases, particularly if both functional and anatomical information are acquired and accurately co-registered. Hence, there is a resulting need for multi modality phantoms in order to validate image co-registration and calibrate the imaging systems. We present our PET-ultrasound phantom development, including PET and ultrasound images of a simple prostate phantom. We use agar and gelatin mixed with a radioactive solution. We also present our development of custom multi-modality phantoms that are compatible with PET, transrectal ultrasound (TRUS), MRI and CT imaging. We describe both our selection of tissue mimicking materials and phantom construction procedures. These custom PET-TRUS-CT-MRI prostate phantoms use agargelatin radioactive mixtures with additional contrast agents and preservatives. We show multi-modality images of these custom prostate phantoms, as well as discuss phantom construction alternatives. Although we are currently focused on prostate imaging, this phantom development is applicable to many multi-modality imaging applications.

  20. Multimodal Revision Techniques in Webtexts

    ERIC Educational Resources Information Center

    Ball, Cheryl E.

    2014-01-01

    This article examines how an online scholarly journal, "Kairos: Rhetoric, Technology, Pedagogy," mentors authors to revise their webtexts (interactive, digital media scholarship) for publication. Using an editorial pedagogy in which multimodal and rhetorical genre theories are merged with revision techniques found in process-based…

  1. Exostosis Bursata - Multimodality Imaging Approach.

    PubMed

    Ali, Asik Ali Mohamed; Sharma, Praveen; Rege, Rujuta; Seena, C R; Rajesh, Saveetha

    2016-09-01

    Osteochondromas or exostosis are common benign bone tumours, commonly arising from the metaphyseal region of long bones (femur, humerus, tibia). Osteochondroma of the scapula are rare and cause mechanical irritation leading to bursal formation. We hereby report a case of 30-year-old man who presented with painful chest wall swelling and its multimodality approach to establish the diagnosis.

  2. Multimodal Revision Techniques in Webtexts

    ERIC Educational Resources Information Center

    Ball, Cheryl E.

    2014-01-01

    This article examines how an online scholarly journal, "Kairos: Rhetoric, Technology, Pedagogy," mentors authors to revise their webtexts (interactive, digital media scholarship) for publication. Using an editorial pedagogy in which multimodal and rhetorical genre theories are merged with revision techniques found in process-based…

  3. Multimodality as a Sociolinguistic Resource

    ERIC Educational Resources Information Center

    Collister, Lauren Brittany

    2013-01-01

    This work explores the use of multimodal communication in a community of expert "World of Warcraft"® players and its impact on politeness, identity, and relationships. Players in the community regularly communicated using three linguistic modes quasi-simultaneously: text chat, voice chat, and face-to-face interaction. Using the…

  4. Underwater Multimode Directional Transducer Evaluation

    DTIC Science & Technology

    2003-12-01

    The work described in the present thesis is intended to establish a procedure for analyzing directional transducers for future underwater wireless...networks, as well as to carry out the performance evaluation of a multimode transducer prototype with respect to its main operational requirements

  5. Multimodality as a Sociolinguistic Resource

    ERIC Educational Resources Information Center

    Collister, Lauren Brittany

    2013-01-01

    This work explores the use of multimodal communication in a community of expert "World of Warcraft"® players and its impact on politeness, identity, and relationships. Players in the community regularly communicated using three linguistic modes quasi-simultaneously: text chat, voice chat, and face-to-face interaction. Using the…

  6. Multimode-singlemode-multimode fiber sensor for alcohol sensing application

    NASA Astrophysics Data System (ADS)

    Rofi'ah, Iftihatur; Hatta, A. M.; Sekartedjo, Sekartedjo

    2016-11-01

    Alcohol is volatile and flammable liquid which is soluble substances both on polar and non polar substances that has been used in some industrial sectors. Alcohol detection method now widely used one of them is the optical fiber sensor. In this paper used fiber optic sensor based on Multimode-Single-mode-Multimode (MSM) to detect alcohol solution at a concentration range of 0-3%. The working principle of sensor utilizes the modal interference between the core modes and the cladding modes, thus make the sensor sensitive to environmental changes. The result showed that characteristic of the sensor not affect the length of the single-mode fiber (SMF). We obtain that the sensor with a length of 5 mm of single-mode can sensing the alcohol with a sensitivity of 0.107 dB/v%.

  7. Experimental verification of MMI by singlemode-multimode-singlemode and multimode-singlemode structures

    NASA Astrophysics Data System (ADS)

    Majumder, Saikat; Ghosh, Amarnath; Roy, Bapita; Chakraborty, Rajib

    2015-06-01

    Multimode Interference (MMI) based on self imaging phenomenon is investigated using matrix approach. Experimentally MMI is verified using singlemode-multimode-singlemode and multimodesinglemode structures of optical fiber. The results obtained are also verified by BPM technique.

  8. Gastric Adenocarcinoma: A Multimodal Approach

    PubMed Central

    Quadri, Humair S.; Smaglo, Brandon G.; Morales, Shannon J.; Phillips, Anna Chloe; Martin, Aimee D.; Chalhoub, Walid M.; Haddad, Nadim G.; Unger, Keith R.; Levy, Angela D.; Al-Refaie, Waddah B.

    2017-01-01

    Despite its declining incidence, gastric cancer (GC) remains a leading cause of cancer-related deaths worldwide. A multimodal approach to GC is critical to ensure optimal patient outcomes. Pretherapy fine resolution contrast-enhanced cross-sectional imaging, endoscopic ultrasound and staging laparoscopy play an important role in patients with newly diagnosed ostensibly operable GC to avoid unnecessary non-therapeutic laparotomies. Currently, margin negative gastrectomy and adequate lymphadenectomy performed at high volume hospitals remain the backbone of GC treatment. Importantly, adequate GC surgery should be integrated in the setting of a multimodal treatment approach. Treatment for advanced GC continues to expand with the emergence of additional lines of systemic and targeted therapies. PMID:28824918

  9. Multimodal CT in stroke imaging: new concepts.

    PubMed

    Ledezma, Carlos J; Wintermark, Max

    2009-01-01

    A multimodal CT protocol provides a comprehensive noninvasive survey of acute stroke patients with accurate demonstration of the site of arterial occlusion and its hemodynamic tissue status. It combines widespread availability with the ability to provide functional characterization of cerebral ischemia, and could potentially allow more accurate selection of candidates for acute stroke reperfusion therapy. This article discusses the individual components of multimodal CT and addresses the potential role of a combined multimodal CT stroke protocol in acute stroke therapy.

  10. Multi-Mode Broadband Patch Antenna

    NASA Technical Reports Server (NTRS)

    Romanofsky, Robert R. (Inventor)

    2001-01-01

    A multi-mode broad band patch antenna is provided that allows for the same aperture to be used at independent frequencies such as reception at 19 GHz and transmission at 29 GHz. Furthermore, the multi-mode broadband patch antenna provides a ferroelectric film that allows for tuning capability of the multi-mode broadband patch antenna over a relatively large tuning range. The alternative use of a semiconductor substrate permits reduced control voltages since the semiconductor functions as a counter electrode.

  11. Decoherence of multimode thermal squeezed coherent states

    NASA Technical Reports Server (NTRS)

    Yeh, Leehwa

    1993-01-01

    It is well known that any multimode positive definite quadratic Hamiltonian can be transformed into a Hamiltonian of uncoupled harmonic oscillators. Based on this theorem, the multimode thermal squeezed coherent states are constructed in terms of density operators. Decoherence of multimode thermal squeezed coherent states is investigated via the characteristic function and it is shown that the decohered (reduced) states are still thermal squeezed coherent states in general.

  12. Advances in multimodality molecular imaging

    PubMed Central

    Zaidi, Habib; Prasad, Rameshwar

    2009-01-01

    Multimodality molecular imaging using high resolution positron emission tomography (PET) combined with other modalities is now playing a pivotal role in basic and clinical research. The introduction of combined PET/CT systems in clinical setting has revolutionized the practice of diagnostic imaging. The complementarity between the intrinsically aligned anatomic (CT) and functional or metabolic (PET) information provided in a “one-stop shop” and the possibility to use CT images for attenuation correction of the PET data has been the driving force behind the success of this technology. On the other hand, combining PET with Magnetic Resonance Imaging (MRI) in a single gantry is technically more challenging owing to the strong magnetic fields. Nevertheless, significant progress has been made resulting in the design of few preclinical PET systems and one human prototype dedicated for simultaneous PET/MR brain imaging. This paper discusses recent advances in PET instrumentation and the advantages and challenges of multimodality imaging systems. Future opportunities and the challenges facing the adoption of multimodality imaging instrumentation will also be addressed. PMID:20098557

  13. Multimodal nanoparticulate bioimaging contrast agents.

    PubMed

    Sharma, Parvesh; Singh, Amit; Brown, Scott C; Bengtsson, Niclas; Walter, Glenn A; Grobmyer, Stephen R; Iwakuma, Nobutaka; Santra, Swadeshmukul; Scott, Edward W; Moudgil, Brij M

    2010-01-01

    A wide variety of bioimaging techniques (e.g., ultrasound, computed X-ray tomography, magnetic resonance imaging (MRI), and positron emission tomography) are commonly employed for clinical diagnostics and scientific research. While all of these methods use a characteristic "energy-matter" interaction to provide specific details about biological processes, each modality differs from another in terms of spatial and temporal resolution, anatomical and molecular details, imaging depth, as well as the desirable material properties of contrast agents needed for augmented imaging. On many occasions, it is advantageous to apply multiple complimentary imaging modalities for faster and more accurate prognosis. Since most imaging modalities employ exogenous contrast agents to improve the signal-to-noise ratio, the development and use of multimodal contrast agents is considered to be highly advantageous for obtaining improved imagery from sought-after imaging modalities. Multimodal contrast agents offer improvements in patient care, and at the same time can reduce costs and enhance safety by limiting the number of contrast agent administrations required for imaging purposes. Herein, we describe the synthesis and characterization of nanoparticulate-based multimodal contrast agent for noninvasive bioimaging using MRI, optical, and photoacoustic tomography (PAT)-imaging modalities. The synthesis of these agents is described using microemulsions, which enable facile integration of the desired diversity of contrast agents and material components into a single entity.

  14. Multimodal Estimation of Distribution Algorithms.

    PubMed

    Yang, Qiang; Chen, Wei-Neng; Li, Yun; Chen, C L Philip; Xu, Xiang-Min; Zhang, Jun

    2016-02-15

    Taking the advantage of estimation of distribution algorithms (EDAs) in preserving high diversity, this paper proposes a multimodal EDA. Integrated with clustering strategies for crowding and speciation, two versions of this algorithm are developed, which operate at the niche level. Then these two algorithms are equipped with three distinctive techniques: 1) a dynamic cluster sizing strategy; 2) an alternative utilization of Gaussian and Cauchy distributions to generate offspring; and 3) an adaptive local search. The dynamic cluster sizing affords a potential balance between exploration and exploitation and reduces the sensitivity to the cluster size in the niching methods. Taking advantages of Gaussian and Cauchy distributions, we generate the offspring at the niche level through alternatively using these two distributions. Such utilization can also potentially offer a balance between exploration and exploitation. Further, solution accuracy is enhanced through a new local search scheme probabilistically conducted around seeds of niches with probabilities determined self-adaptively according to fitness values of these seeds. Extensive experiments conducted on 20 benchmark multimodal problems confirm that both algorithms can achieve competitive performance compared with several state-of-the-art multimodal algorithms, which is supported by nonparametric tests. Especially, the proposed algorithms are very promising for complex problems with many local optima.

  15. Radioactive Nanomaterials for Multimodality Imaging

    PubMed Central

    Chen, Daiqin; Dougherty, Casey A.; Yang, Dongzhi; Wu, Hongwei; Hong, Hao

    2016-01-01

    Nuclear imaging techniques, including primarily positron emission tomography (PET) and single-photon emission computed tomography (SPECT), can provide quantitative information for a biological event in vivo with ultra-high sensitivity, however, the comparatively low spatial resolution is their major limitation in clinical application. By convergence of nuclear imaging with other imaging modalities like computed tomography (CT), magnetic resonance imaging (MRI) and optical imaging, the hybrid imaging platforms can overcome the limitations from each individual imaging technique. Possessing versatile chemical linking ability and good cargo-loading capacity, radioactive nanomaterials can serve as ideal imaging contrast agents. In this review, we provide a brief overview about current state-of-the-art applications of radioactive nanomaterials in the circumstances of multimodality imaging. We present strategies for incorporation of radioisotope(s) into nanomaterials along with applications of radioactive nanomaterials in multimodal imaging. Advantages and limitations of radioactive nanomaterials for multimodal imaging applications are discussed. Finally, a future perspective of possible radioactive nanomaterial utilization is presented for improving diagnosis and patient management in a variety of diseases. PMID:27227167

  16. Multimodal Distribution of Human Cold Pain Thresholds

    PubMed Central

    Lötsch, Jörn; Dimova, Violeta; Lieb, Isabel; Zimmermann, Michael; Oertel, Bruno G.; Ultsch, Alfred

    2015-01-01

    Background It is assumed that different pain phenotypes are based on varying molecular pathomechanisms. Distinct ion channels seem to be associated with the perception of cold pain, in particular TRPM8 and TRPA1 have been highlighted previously. The present study analyzed the distribution of cold pain thresholds with focus at describing the multimodality based on the hypothesis that it reflects a contribution of distinct ion channels. Methods Cold pain thresholds (CPT) were available from 329 healthy volunteers (aged 18 – 37 years; 159 men) enrolled in previous studies. The distribution of the pooled and log-transformed threshold data was described using a kernel density estimation (Pareto Density Estimation (PDE)) and subsequently, the log data was modeled as a mixture of Gaussian distributions using the expectation maximization (EM) algorithm to optimize the fit. Results CPTs were clearly multi-modally distributed. Fitting a Gaussian Mixture Model (GMM) to the log-transformed threshold data revealed that the best fit is obtained when applying a three-model distribution pattern. The modes of the identified three Gaussian distributions, retransformed from the log domain to the mean stimulation temperatures at which the subjects had indicated pain thresholds, were obtained at 23.7 °C, 13.2 °C and 1.5 °C for Gaussian #1, #2 and #3, respectively. Conclusions The localization of the first and second Gaussians was interpreted as reflecting the contribution of two different cold sensors. From the calculated localization of the modes of the first two Gaussians, the hypothesis of an involvement of TRPM8, sensing temperatures from 25 – 24 °C, and TRPA1, sensing cold from 17 °C can be derived. In that case, subjects belonging to either Gaussian would possess a dominance of the one or the other receptor at the skin area where the cold stimuli had been applied. The findings therefore support a suitability of complex analytical approaches to detect mechanistically

  17. A cuckoo search algorithm for multimodal optimization.

    PubMed

    Cuevas, Erik; Reyna-Orta, Adolfo

    2014-01-01

    Interest in multimodal optimization is expanding rapidly, since many practical engineering problems demand the localization of multiple optima within a search space. On the other hand, the cuckoo search (CS) algorithm is a simple and effective global optimization algorithm which can not be directly applied to solve multimodal optimization problems. This paper proposes a new multimodal optimization algorithm called the multimodal cuckoo search (MCS). Under MCS, the original CS is enhanced with multimodal capacities by means of (1) the incorporation of a memory mechanism to efficiently register potential local optima according to their fitness value and the distance to other potential solutions, (2) the modification of the original CS individual selection strategy to accelerate the detection process of new local minima, and (3) the inclusion of a depuration procedure to cyclically eliminate duplicated memory elements. The performance of the proposed approach is compared to several state-of-the-art multimodal optimization algorithms considering a benchmark suite of fourteen multimodal problems. Experimental results indicate that the proposed strategy is capable of providing better and even a more consistent performance over existing well-known multimodal algorithms for the majority of test problems yet avoiding any serious computational deterioration.

  18. Multimodal Literacies in the Secondary English Classroom

    ERIC Educational Resources Information Center

    Sewell, William C.; Denton, Shawn

    2011-01-01

    To provide insight into the issue of multimodal literacy instruction, the authors explore presentation techniques and instructional activities employed in their secondary language arts classes. They collaborate on assignments that focus students on "anchored media instruction" and engage them in producing multimodal, technology-infused projects,…

  19. Multimodal Narrative Inquiry: Six Teacher Candidates Respond

    ERIC Educational Resources Information Center

    Morawski, Cynthia M.; Rottmann, Jennifer

    2016-01-01

    In this paper we present findings of a study on the implementation of a multimodal teacher narrative inquiry component, theoretically grounded by Rosenblatt's theory of transaction analysis, methodologically supported by action research and practically enacted by narrative inquiry and multimodal learning. In particular, the component offered…

  20. Multimode optical fibers: steady state mode exciter.

    PubMed

    Ikeda, M; Sugimura, A; Ikegami, T

    1976-09-01

    The steady state mode power distribution of the multimode graded index fiber was measured. A simple and effective steady state mode exciter was fabricated by an etching technique. Its insertion loss was 0.5 dB for an injection laser. Deviation in transmission characteristics of multimode graded index fibers can be avoided by using the steady state mode exciter.

  1. A Cuckoo Search Algorithm for Multimodal Optimization

    PubMed Central

    2014-01-01

    Interest in multimodal optimization is expanding rapidly, since many practical engineering problems demand the localization of multiple optima within a search space. On the other hand, the cuckoo search (CS) algorithm is a simple and effective global optimization algorithm which can not be directly applied to solve multimodal optimization problems. This paper proposes a new multimodal optimization algorithm called the multimodal cuckoo search (MCS). Under MCS, the original CS is enhanced with multimodal capacities by means of (1) the incorporation of a memory mechanism to efficiently register potential local optima according to their fitness value and the distance to other potential solutions, (2) the modification of the original CS individual selection strategy to accelerate the detection process of new local minima, and (3) the inclusion of a depuration procedure to cyclically eliminate duplicated memory elements. The performance of the proposed approach is compared to several state-of-the-art multimodal optimization algorithms considering a benchmark suite of fourteen multimodal problems. Experimental results indicate that the proposed strategy is capable of providing better and even a more consistent performance over existing well-known multimodal algorithms for the majority of test problems yet avoiding any serious computational deterioration. PMID:25147850

  2. Multimodality, Literacy and Texts: Developing a Discourse

    ERIC Educational Resources Information Center

    Bearne, Eve

    2009-01-01

    This article argues for the development of a framework through which to describe children's multimodal texts. Such a shared discourse should be capable of including different modes and media and the ways in which children integrate and combine them for their own meaning-making purposes. It should also acknowledge that multimodal texts are not…

  3. Filter. Remix. Make.: Cultivating Adaptability through Multimodality

    ERIC Educational Resources Information Center

    Dusenberry, Lisa; Hutter, Liz; Robinson, Joy

    2015-01-01

    This article establishes traits of adaptable communicators in the 21st century, explains why adaptability should be a goal of technical communication educators, and shows how multimodal pedagogy supports adaptability. Three examples of scalable, multimodal assignments (infographics, research interviews, and software demonstrations) that evidence…

  4. Filter. Remix. Make.: Cultivating Adaptability through Multimodality

    ERIC Educational Resources Information Center

    Dusenberry, Lisa; Hutter, Liz; Robinson, Joy

    2015-01-01

    This article establishes traits of adaptable communicators in the 21st century, explains why adaptability should be a goal of technical communication educators, and shows how multimodal pedagogy supports adaptability. Three examples of scalable, multimodal assignments (infographics, research interviews, and software demonstrations) that evidence…

  5. Evaluating Multimodal Literacies in Student Blogs

    ERIC Educational Resources Information Center

    O'Byrne, Barbara; Murrell, Stacey

    2014-01-01

    This research presents ways in which high school students used the multimodal and interactive affordances of blogs to create, organize, communicate and participate on an educational blog. Their actions demonstrated how plural modes of literacy are infiltrating digital environments and reshaping literacy and learning. Multimodal blogging practices…

  6. Radiolabeled Nanoparticles for Multimodality Tumor Imaging

    PubMed Central

    Xing, Yan; Zhao, Jinhua; Conti, Peter S.; Chen, Kai

    2014-01-01

    Each imaging modality has its own unique strengths. Multimodality imaging, taking advantages of strengths from two or more imaging modalities, can provide overall structural, functional, and molecular information, offering the prospect of improved diagnostic and therapeutic monitoring abilities. The devices of molecular imaging with multimodality and multifunction are of great value for cancer diagnosis and treatment, and greatly accelerate the development of radionuclide-based multimodal molecular imaging. Radiolabeled nanoparticles bearing intrinsic properties have gained great interest in multimodality tumor imaging over the past decade. Significant breakthrough has been made toward the development of various radiolabeled nanoparticles, which can be used as novel cancer diagnostic tools in multimodality imaging systems. It is expected that quantitative multimodality imaging with multifunctional radiolabeled nanoparticles will afford accurate and precise assessment of biological signatures in cancer in a real-time manner and thus, pave the path towards personalized cancer medicine. This review addresses advantages and challenges in developing multimodality imaging probes by using different types of nanoparticles, and summarizes the recent advances in the applications of radiolabeled nanoparticles for multimodal imaging of tumor. The key issues involved in the translation of radiolabeled nanoparticles to the clinic are also discussed. PMID:24505237

  7. Blending with Purpose: The Multimodal Model

    ERIC Educational Resources Information Center

    Picciano, Anthony G.

    2009-01-01

    The purpose of this article is to propose a blending with purpose multimodal conceptual model for designing and developing blended learning courses and programs. A blended learning model is presented that suggests teachers design instruction to meet the needs of a variety of learners. Specifically, "Blending with Purpose: The Multimodal Model"…

  8. Multimodal Pedagogies for Teacher Education in TESOL

    ERIC Educational Resources Information Center

    Yi, Youngjoo; Angay-Crowder, Tuba

    2016-01-01

    As a growing number of English language learners (ELLs) engage in digital and multimodal literacy practices in their daily lives, teachers are starting to incorporate multimodal approaches into their instruction. However, anecdotal and empirical evidence shows that teachers often feel unprepared for integrating such practices into their curricula…

  9. Evaluating Multimodal Literacies in Student Blogs

    ERIC Educational Resources Information Center

    O'Byrne, Barbara; Murrell, Stacey

    2014-01-01

    This research presents ways in which high school students used the multimodal and interactive affordances of blogs to create, organize, communicate and participate on an educational blog. Their actions demonstrated how plural modes of literacy are infiltrating digital environments and reshaping literacy and learning. Multimodal blogging practices…

  10. Literacy, Media and Multimodality: A Critical Response

    ERIC Educational Resources Information Center

    Bazalgette, Cary; Buckingham, David

    2013-01-01

    In recent years, literacy educators have increasingly recognised the importance of addressing a broader range of texts in the classroom. This article raises some critical concerns about a particular approach to this issue that has been widely promoted in recent years-- the concept of "multimodality". Multimodality theory offers a broadly…

  11. Drusen Characterization with Multimodal Imaging

    PubMed Central

    Spaide, Richard F.; Curcio, Christine A.

    2010-01-01

    Summary Multimodal imaging findings and histological demonstration of soft drusen, cuticular drusen, and subretinal drusenoid deposits provided information used to develop a model explaining their imaging characteristics. Purpose To characterize the known appearance of cuticular drusen, subretinal drusenoid deposits (reticular pseudodrusen), and soft drusen as revealed by multimodal fundus imaging; to create an explanatory model that accounts for these observations. Methods Reported color, fluorescein angiographic, autofluorescence, and spectral domain optical coherence tomography (SD-OCT) images of patients with cuticular drusen, soft drusen, and subretinal drusenoid deposits were reviewed, as were actual images from affected eyes. Representative histological sections were examined. The geometry, location, and imaging characteristics of these lesions were evaluated. A hypothesis based on the Beer-Lambert Law of light absorption was generated to fit these observations. Results Cuticular drusen appear as numerous uniform round yellow-white punctate accumulations under the retinal pigment epithelium (RPE). Soft drusen are larger yellow-white dome-shaped mounds of deposit under the RPE. Subretinal drusenoid deposits are polymorphous light-grey interconnected accumulations above the RPE. Based on the model, both cuticular and soft drusen appear yellow due to the removal of shorter wavelength light by a double pass through the RPE. Subretinal drusenoid deposits, which are located on the RPE, are not subjected to short wavelength attenuation and therefore are more prominent when viewed with blue light. The location and morphology of extracellular material in relationship to the RPE, and associated changes to RPE morphology and pigmentation, appeared to be primary determinants of druse appearance in different imaging modalities. Conclusion Although cuticular drusen, subretinal drusenoid deposits, and soft drusen are composed of common components, they are distinguishable

  12. Multimodal Treatment of Chronic Pain.

    PubMed

    Dale, Rebecca; Stacey, Brett

    2016-01-01

    Most patients with chronic pain receive multimodal treatment. There is scant literature to guide us, but when approaching combination pharmacotherapy, the practitioner and patient must weigh the benefits with the side effects; many medications have modest effect yet carry significant side effects that can be additive. Chronic pain often leads to depression, anxiety, and deconditioning, which are targets for treatment. Structured interdisciplinary programs are beneficial but costly. Interventions have their place in the treatment of chronic pain and should be a part of a multidisciplinary treatment plan. Further research is needed to validate many common combination treatments. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Metawidgets in the multimodal interface

    SciTech Connect

    Blattner, M.M. Anderson Cancer Center, Houston, TX ); Glinert, E.P.; Jorge, J.A.; Ormsby, G.R. . Dept. of Computer Science)

    1991-01-01

    We analyze two intertwined and fundamental issues concerning computer-to-human communication in the multimodal interfaces: the interplay between sound and graphics, and the role of object persistence. Our observations lead us to introduce metawidgets as abstract entities capable of manifesting themselves to users as image, as sound, or as various combinations and/or sequences of the two media. We show examples of metawidgets in action, and discuss mechanisms for choosing among alternative media for metawidget instantiation. Finally, we describe a couple of experimental microworlds we have implemented to test out some of our ideas. 17 refs., 7 figs.

  14. Untangled modes in multimode waveguides

    NASA Astrophysics Data System (ADS)

    Plöschner, Martin; Tyc, TomáÅ.¡; Čižmár, TomáÅ.¡

    2016-03-01

    Small, fibre-based endoscopes have already improved our ability to image deep within the human body. A novel approach introduced recently utilised disordered light within a standard multimode optical fibre for lensless imaging. Importantly, this approach brought very significant reduction of the instruments footprint to dimensions below 100 μm. The most important limitations of this exciting technology is the lack of bending flexibility - imaging is only possible as long as the fibre remains stationary. The only route to allow flexibility of such endoscopes is in trading-in all the knowledge about the optical system we have, particularly the cylindrical symmetry of refractive index distribution. In perfect straight step-index cylindrical waveguides we can find optical modes that do not change their spatial distribution as they propagate through. In this paper we present a theoretical background that provides description of such modes in more realistic model of real-life step-index multimode fibre taking into account common deviations in distribution of the refractive index from its ideal step-index profile. Separately, we discuss how to include the influence of fibre bending.

  15. Multimodality localization of epileptic foci

    NASA Astrophysics Data System (ADS)

    Desco, Manuel; Pascau, Javier; Pozo, M. A.; Santos, Andres; Reig, Santiago; Gispert, Juan D.; Garcia-Barreno, Pedro

    2001-05-01

    This paper presents a multimodality approach for the localization of epileptic foci using PET, MRI and EEG combined without the need of external markers. Mutual Information algorithm is used for MRI-PET registration. Dipole coordinates (provided by BESA software) are projected onto the MRI using a specifically developed algorithm. The four anatomical references used for electrode positioning (nasion, inion and two preauricular points) are located on the MRI using a triplanar viewer combined with a surface-rendering tool. Geometric transformation using deformation of the ideal sphere used for dipole calculations is then applied to match the patient's brain size and shape. Eight treatment-refractory epileptic patients have been studied. The combination of the anatomical information from the MRI, hipoperfusion areas in PET and dipole position and orientation helped the physician in the diagnosis of epileptic focus location. Neurosurgery was not indicated for patients where PET and dipole results were inconsistent; in two cases it was clinically indicated despite the mismatch, showing a negative follow up. The multimodality approach presented does not require external markers for dipole projection onto the MRI, this being the main difference with previous methods. The proposed method may play an important role in the indication of surgery for treatment- refractory epileptic patients.

  16. Multimodal signature modeling of humans

    NASA Astrophysics Data System (ADS)

    Cathcart, J. Michael; Kocher, Brian; Prussing, Keith; Lane, Sarah; Thomas, Alan

    2010-04-01

    Georgia Tech been investigating method for the detection of covert personnel in traditionally difficult environments (e.g., urban, caves). This program focuses on a detailed phenomenological analysis of human physiology and signatures with the subsequent identification and characterization of potential observables. Both aspects are needed to support the development of personnel detection and tracking algorithms. The difficult nature of these personnel-related problems dictates a multimodal sensing approach. Human signature data of sufficient and accurate quality and quantity do not exist, thus the development of an accurate signature model for a human is needed. This model should also simulate various human activities to allow motion-based observables to be exploited. This paper will describe a multimodal signature modeling approach that incorporates human physiological aspects, thermoregulation, and dynamics into the signature calculation. This approach permits both passive and active signatures to be modeled. The focus of the current effort involved the computation of signatures in urban environments. This paper will discuss the development of a human motion model for use in simulating both electro-optical signatures and radar-based signatures. Video sequences of humans in a simulated urban environment will also be presented; results using these sequences for personnel tracking will be presented.

  17. Practical multimodal care for cancer cachexia

    PubMed Central

    Maddocks, Matthew; Hopkinson, Jane; Conibear, John; Reeves, Annie; Shaw, Clare; Fearon, Ken C.H.

    2016-01-01

    Purpose of review Cancer cachexia is common and reduces function, treatment tolerability and quality of life. Given its multifaceted pathophysiology a multimodal approach to cachexia management is advocated for, but can be difficult to realise in practice. We use a case-based approach to highlight practical approaches to the multimodal management of cachexia for patients across the cancer trajectory. Recent findings Four cases with lung cancer spanning surgical resection, radical chemoradiotherapy, palliative chemotherapy and no anticancer treatment are presented. We propose multimodal care approaches that incorporate nutritional support, exercise, and anti-inflammatory agents, on a background of personalized oncology care and family-centred education. Collectively, the cases reveal that multimodal care is part of everyone's remit, often focuses on supported self-management, and demands buy-in from the patient and their family. Once operationalized, multimodal care approaches can be tested pragmatically, including alongside emerging pharmacological cachexia treatments. Summary We demonstrate that multimodal care for cancer cachexia can be achieved using simple treatments and without a dedicated team of specialists. The sharing of advice between health professionals can help build collective confidence and expertise, moving towards a position in which every team member feels they can contribute towards multimodal care. PMID:27635765

  18. A quantitative framework for the analysis of multimodal optical microscopy images

    PubMed Central

    Bower, Andrew J.; Chidester, Benjamin; Li, Joanne; Zhao, Youbo; Marjanovic, Marina; Chaney, Eric J.; Do, Minh N.

    2017-01-01

    Background Multimodal optical microscopy, a set of imaging techniques based on unique, yet complementary contrast mechanisms and spatially and temporally co-registered data acquisition, has emerged as a powerful biomedical tool. However, the analysis of the dense, high-dimensional datasets acquired by these instruments remains mostly qualitative and restricted to analysis of each modality individually. Methods Using a custom-built multimodal nonlinear optical microscope, high dimensional datasets were acquired for automated classification of functional cell states as well as identification of histopathological features in tissues slices. Supervised classification of cell death modes was performed through support vector machines (SVM) and semi-supervised classification of tissue slices was performed through the use of the expectation maximization (EM) algorithm. Results Applications of these techniques to the automated classification of cell death modes as well as to the identification of tissue components in fixed ex vivo tissue slices are presented. The analysis techniques developed provide a direct link between multimodal image contrast and biological structure and function, resulting in highly accurate classification in both settings. Conclusions Quantification of multimodal optical microscopy images through statistical modeling of the high dimensional data acquired gives a strong correlation between biological structure and function and image contrast. These methods are sensitive to the identification of diagnostic, cellular-level features important in a variety of clinical settings. PMID:28275557

  19. Multimodal Dispersion of Nanoparticles: A Comprehensive Evaluation of Size Distribution with 9 Size Measurement Methods.

    PubMed

    Varenne, Fanny; Makky, Ali; Gaucher-Delmas, Mireille; Violleau, Frédéric; Vauthier, Christine

    2016-05-01

    Evaluation of particle size distribution (PSD) of multimodal dispersion of nanoparticles is a difficult task due to inherent limitations of size measurement methods. The present work reports the evaluation of PSD of a dispersion of poly(isobutylcyanoacrylate) nanoparticles decorated with dextran known as multimodal and developed as nanomedecine. The nine methods used were classified as batch particle i.e. Static Light Scattering (SLS) and Dynamic Light Scattering (DLS), single particle i.e. Electron Microscopy (EM), Atomic Force Microscopy (AFM), Tunable Resistive Pulse Sensing (TRPS) and Nanoparticle Tracking Analysis (NTA) and separative particle i.e. Asymmetrical Flow Field-Flow Fractionation coupled with DLS (AsFlFFF) size measurement methods. The multimodal dispersion was identified using AFM, TRPS and NTA and results were consistent with those provided with the method based on a separation step prior to on-line size measurements. None of the light scattering batch methods could reveal the complexity of the PSD of the dispersion. Difference between PSD obtained from all size measurement methods tested suggested that study of the PSD of multimodal dispersion required to analyze samples by at least one of the single size particle measurement method or a method that uses a separation step prior PSD measurement.

  20. Brain Multimodality Monitoring: Updated Perspectives

    PubMed Central

    Roh, David

    2016-01-01

    The challenges posed by acute brain injury (ABI) involve the management of the initial insult in addition to downstream inflammation, edema, and ischemia that can result in secondary brain injury (SBI). SBI is often subclinical, but can be detected through physiologic changes. These changes serve as a surrogate for tissue injury/cell death and are captured by parameters measured by various monitors that measure intracranial pressure (ICP), cerebral blood flow (CBF), brain tissue oxygenation (PbtO2), cerebral metabolism, and electrocortical activity. In the ideal setting, multimodality monitoring (MMM) integrates these neurological monitoring parameters with traditional hemodynamic monitoring and the physical exam, presenting the information needed to clinicians who can intervene before irreversible damage occurs. There are now consensus guidelines on the utilization of MMM, and there continue to be new advances and questions regarding its use. In this review, we examine these recommendations, recent evidence for MMM, and future directions for MMM. PMID:27095434

  1. Multimodal unattended ground sensor (MMUGS)

    NASA Astrophysics Data System (ADS)

    Zong, Lei; Houser, Jeff; Damarla, T. Raju

    2006-05-01

    The U.S. Army Research Laboratory has developed a real-time multi-modal sensor for the purpose of personnel detection in urban terrain. Possible system usage includes force protection and sniper early warning. The sensor system includes a network of MMUGS sensors, a third-party gateway and user interface device. A MMUGS sensor consists of the following functions: sensing, processing, and communication. Each sensor is composed of multiple sensing modalities-acoustic, passive-infrared, and seismic. A MMUGS sensor is designed to be low cost and power efficient. This paper will first present an overview of the sensor architecture and then provide detailed descriptions of sub components. The paper will conclude with a detailed analysis of system performance. This paper is intended to provide details of the design, integration, and implementation of a MMUGS unit, and demonstrate the overall sensor system performance. This paper does not discuss the network aspect of the system and its affect on performance.

  2. Multimode waveguide based directional coupler

    NASA Astrophysics Data System (ADS)

    Ahmed, Rajib; Rifat, Ahmmed A.; Sabouri, Aydin; Al-Qattan, Bader; Essa, Khamis; Butt, Haider

    2016-07-01

    The Silicon-on-Insulator (SOI) based platform overcomes limitations of the previous copper and fiber based technologies. Due to its high index difference, SOI waveguide (WG) and directional couplers (DC) are widely used for high speed optical networks and hybrid Electro-Optical inter-connections; TE00-TE01, TE00-TE00 and TM00-TM00 SOI direction couplers are designed with symmetrical and asymmetrical configurations to couple with TE00, TE01 and TM00 in a multi-mode semi-triangular ring-resonator configuration which will be applicable for multi-analyte sensing. Couplers are designed with effective index method and their structural parameters are optimized with consideration to coupler length, wavelength and polarization dependence. Lastly, performance of the couplers are analyzed in terms of cross-talk, mode overlap factor, coupling length and coupling efficiency.

  3. [Multimodal pain therapy. Current situation].

    PubMed

    Kaiser, U; Sabatowski, R; Azad, S C

    2015-10-01

    A multidisciplinary approach for the management of patients with chronic pain is now well-established in many countries, especially in situations involving a complex disease process in the sense of a biopsychosocial model. Both the efficacy and cost-effectiveness of multidisciplinary pain treatment programs and their superiority compared to unimodal therapy has been documented in a number of studies, reviews and meta-analyses, in particular for patients suffering from chronic low back pain. Nevertheless, there are still major shortcomings concerning the definition of multimodal and multidisciplinary treatment and the quality of structures and processes, compared for example to the standards defined by the German Pain Society (Deutsche Schmerzgesellschaft). Furthermore, there is still no consensus on specific therapeutic approaches, the differentiation between responders and non-responders as well as on the tools required for measurement. All these questions will have to be answered by concerted efforts in a multicenter setting.

  4. DBSAR's First Multimode Flight Campaign

    NASA Technical Reports Server (NTRS)

    Rincon, Rafael F.; Vega, Manuel; Buenfil, Manuel; Geist, Alessandro; Hilliard, Lawrence; Racette, Paul

    2010-01-01

    The Digital Beamforming SAR (DBSAR) is an airborne imaging radar system that combines phased array technology, reconfigurable on-board processing and waveform generation, and advances in signal processing to enable techniques not possible with conventional SARs. The system exploits the versatility inherently in phased-array technology with a state-of-the-art data acquisition and real-time processor in order to implement multi-mode measurement techniques in a single radar system. Operational modes include scatterometry over multiple antenna beams, Synthetic Aperture Radar (SAR) over several antenna beams, or Altimetry. The radar was flight tested in October 2008 on board of the NASA P3 aircraft over the Delmarva Peninsula, MD. The results from the DBSAR system performance is presented.

  5. Multimodal Imaging in Sympathetic Ophthalmia.

    PubMed

    Mahajan, Sarakshi; Invernizzi, Alessandro; Agrawal, Rupesh; Biswas, Jyotirmay; Rao, Narsing A; Gupta, Vishali

    2017-04-01

    To show the current status of multimodal imaging and its role in supporting an early diagnosis of sympathetic ophthalmia. The diagnosis is mainly clinical supported with ancillary investigations; mainly fluorescein angiography and others, including indocyanine angiography optical coherence tomography (OCT), OCT enhanced depth imaging, autofluorescence imaging, and ultrasonography. Various imaging modalities such as OCT, autofluorescence imaging and angiography are critical in the diagnosis and management of sympathetic ophthalmia. The clinician must make adequate use of such ancillary investigations in the management of the patients. Sympathetic ophthalmia is a rare, bilateral inflammation of the uveal tract following penetrating trauma or surgery in one eye. The intraocular inflammation requires a prompt diagnosis so that the treatment can be initiated as early as possible.

  6. Multimodal MRI of experimental stroke

    PubMed Central

    Duong, Timothy Q

    2014-01-01

    Stroke is the fourth leading cause of death and the leading cause of long-term disability in the United States. Brain imaging data from experimental stroke models and stroke patients have shown that there is often a gradual progression of potentially reversible ischemic injury toward infarction. Reestablishing tissue perfusion and/or treating with neuroprotective drugs in a timely fashion are expected to salvage some ischemic tissues. Diffusion-weighted imaging based on magnetic resonance imaging (MRI) in which contrast is based on water motion can detect ischemic injury within minutes after onsets, whereas computed tomography and other imaging modalities fail to detect stroke injury for at least a few hours. Along with quantitative perfusion imaging, the perfusion-diffusion mismatch which approximates the ischemic penumbra could be imaged non-invasively. This review describes recent progresses in the development and application of multimodal MRI and image analysis techniques to study ischemic tissue at risk in experimental stroke in rats. PMID:24323751

  7. Multimodality nanotracers for cardiovascular applications.

    PubMed

    Mulder, Willem J M; Cormode, David P; Hak, Sjoerd; Lobatto, Mark E; Silvera, Stephane; Fayad, Zahi A

    2008-08-01

    Targeted imaging and therapeutics is becoming a field of prime importance in the study and treatment of cardiovascular disease; it promises to enable early diagnosis, promote improved understanding of pathology, and offer a way to improve therapeutic efficacy. Agents, particularly for cardiovascular disease, have been reported to permit the in vivo imaging, by multiple modalities, of macrophages, vascular targets such as vascular cell adhesion molecule 1, and markers for angiogenesis such as alpha(v)beta(3) integrin. In this Article, we first discuss the general concept of multimodality nanoparticles and then focus in greater depth on their clinical application for molecular imaging and therapy. Lastly, several examples of cardiovascular applications are discussed, including combined imaging and therapy approaches.

  8. An innovative multimodal/multispectral image registration method for medical images based on the Expectation-Maximization algorithm.

    PubMed

    Arce-Santana, Edgar; Campos-Delgado, Daniel U; Mejia-Rodriguez, Aldo; Reducindo, Isnardo

    2015-01-01

    In this paper, we present a methodology for multimodal/ multispectral image registration of medical images. This approach is formulated by using the Expectation-Maximization (EM) methodology, such that we estimate the parameters of a geometric transformation that aligns multimodal/multispectral images. In this framework, the hidden random variables are associated to the intensity relations between the studied images, which allow to compare multispectral intensity values between images of different modalities. The methodology is basically composed by an iterative two-step procedure, where at each step, a new estimation of the joint conditional multispectral intensity distribution and the geometric transformation is computed. The proposed algorithm was tested with different kinds of medical images, and the obtained results show that the proposed methodology can be used to efficiently align multimodal/multispectral medical images.

  9. Multi-Modal Treatment of Nocturnal Enuresis.

    ERIC Educational Resources Information Center

    Mohr, Caroline; Sharpley, Christopher F.

    1988-01-01

    The article reports a multimodal treatment of nocturnal enuresis and anxious behavior in a mildly mentally retarded woman. Behavioral treatment and removal of caffeine from the subject's diet eliminated both nocturnal enuresis and anxious behavior. (Author/DB)

  10. Multi-mode horn antenna simulation

    NASA Technical Reports Server (NTRS)

    Dod, L. R.; Wolf, J. D.

    1980-01-01

    Radiation patterns were computed for a circular multimode horn antenna using waveguide electric field radiation expressions. The circular multimode horn was considered as a possible reflector feed antenna for the Large Antenna Multifrequency Microwave Radiometer (LAMMR). This horn antenna uses a summation of the TE sub 11 deg and TM sub 11 deg modes to generate far field primary radiation patterns with equal E and H plane beamwidths and low sidelobes. A computer program for the radiation field expressions using the summation of waveguide radiation modes is described. The sensitivity of the multimode horn antenna radiation patterns to phase variations between the two modes is given. Sample radiation pattern calculations for a reflector feed horn for LAMMR are shown. The multimode horn antenna provides a low noise feed suitable for radiometric applications.

  11. Histology image search using multimodal fusion.

    PubMed

    Caicedo, Juan C; Vanegas, Jorge A; Páez, Fabian; González, Fabio A

    2014-10-01

    This work proposes a histology image indexing strategy based on multimodal representations obtained from the combination of visual features and associated semantic annotations. Both data modalities are complementary information sources for an image retrieval system, since visual features lack explicit semantic information and semantic terms do not usually describe the visual appearance of images. The paper proposes a novel strategy to build a fused image representation using matrix factorization algorithms and data reconstruction principles to generate a set of multimodal features. The methodology can seamlessly recover the multimodal representation of images without semantic annotations, allowing us to index new images using visual features only, and also accepting single example images as queries. Experimental evaluations on three different histology image data sets show that our strategy is a simple, yet effective approach to building multimodal representations for histology image search, and outperforms the response of the popular late fusion approach to combine information.

  12. Multi-Modal Treatment of Nocturnal Enuresis.

    ERIC Educational Resources Information Center

    Mohr, Caroline; Sharpley, Christopher F.

    1988-01-01

    The article reports a multimodal treatment of nocturnal enuresis and anxious behavior in a mildly mentally retarded woman. Behavioral treatment and removal of caffeine from the subject's diet eliminated both nocturnal enuresis and anxious behavior. (Author/DB)

  13. Treatment Approaches for Interstitial Cystitis: Multimodality Therapy

    PubMed Central

    Evans, Robert J

    2002-01-01

    Interstitial cystitis is an increasingly common disease characterized by urgency, frequency, and pelvic pain. Its etiology is poorly understood but is likely to be multifactorial. A proposed pathophysiology describing a cascade of events, including epithelial dysfunction, mast cell activation, and neurogenic inflammation, is presented. Using this model, multimodality therapy regimens have been developed that treat all components of this cascade. Multimodality therapy appears more effective than single agents in the treatment of interstitial cystitis. PMID:16986029

  14. Reliability of aircraft multimode optical networks

    NASA Astrophysics Data System (ADS)

    Bohata, Jan; Písařík, Michael; Zvánovec, Stanislav; Peterka, Pavel

    2014-09-01

    Results from tests and analyses of multimode optical fibers for an avionic optical network under a variety of stress conditions are presented. Experiments revealed vibrational and temperature changes of distinct multimode fibers. Results lead to the discussion of influenced insertion losses and especially reduced bandwidth corresponding to modal distribution changes. It was determined that these crucial parameters could affect system reliability when an airplane network intersects thermal and vibrational variable environments.

  15. Esthesioneuroblastoma: Multimodal management and review of literature

    PubMed Central

    Kumar, Ritesh

    2015-01-01

    Esthesioneuroblastoma (ENB) is a rare malignant neoplasm arising from the olfactory neuroepithelium. ENB constitutes only 3% of all malignant intranasal neoplasm. Because of the rarity, the number of patients of ENB treated in individual departments is small. Most of these patients presents in locally advanced stages and require multimodality treatment in form of surgery, chemotherapy and radiotherapy. Multimodality approach with a risk-adapted strategy is required to achieve good control rates while minimizing treatment related toxicity. PMID:26380824

  16. Rapid prototype modeling in a multimodality world

    NASA Astrophysics Data System (ADS)

    Bidaut, Luc; Madewell, John; Yasko, Alan

    2006-03-01

    Introduction: Rapid prototype modeling (RPM) has been used in medicine principally for bones - that are easily extracted from CT data sets - for planning orthopaedic, plastic or maxillo-facial interventions, and/or for designing custom prostheses and implants. Based on newly available technology, highly valuable multimodality approaches can now be applied to RPM, particularly for complex musculo-skeletal (MSK) tumors where multimodality often transcends CT alone. Methods: CT data sets are acquired for primary evaluation of MSK tumors in parallel with other modalities (e.g., MR, PET, SPECT). In our approach, CT is first segmented to provide bony anatomy for RPM and all other data sets are then registered to the CT reference. Parametric information relevant to the tumor's characterization is then extracted from the multimodality space and merged with the CT anatomy to produce a hybrid RPM-ready model. This model - that also accommodates digital multimodality visualization - is then produced on the latest generation of 3D printers, which permits both shapes and colors. Results: Multimodality models of complex MSK tumors have been physically produced on modern RPM equipment. This new approach has been found to be a clear improvement over the previously disconnected physical RPM and digital multimodality visualization. Conclusions: New technical developments keep opening doors to sophisticated medical applications that can directly impact the quality of patient care. Although this early work still deals with bones as base models for RPM, its use to encompass soft tissues is already envisioned for future approaches.

  17. Multimodal pain stimulation of the gastrointestinal tract

    PubMed Central

    Drewes, Asbjørn Mohr; Gregersen, Hans

    2006-01-01

    Understanding and characterization of pain and other sensory symptoms are among the most important issues in the diagnosis and assessment of patient with gastrointestinal disorders. Methods to evoke and assess experimental pain have recently developed into a new area with the possibility for multimodal stimulation (e.g., electrical, mechanical, thermal and chemical stimulation) of different nerves and pain pathways in the human gut. Such methods mimic to a high degree the pain experienced in the clinic. Multimodal pain methods have increased our basic understanding of different peripheral receptors in the gut in health and disease. Together with advanced muscle analysis, the methods have increased our understanding of receptors sensitive to mechanical, chemical and temperature stimuli in diseases, such as systemic sclerosis and diabetes. The methods can also be used to unravel central pain mechanisms, such as those involved in allodynia, hyperalgesia and referred pain. Abnormalities in central pain mechanisms are often seen in patients with chronic gut pain and hence methods relying on multimodal pain stimulation may help to understand the symptoms in these patients. Sex differences have been observed in several diseases of the gut, and differences in central pain processing between males and females have been hypothesized using multimodal pain stimulations. Finally, multimodal methods have recently been used to gain more insight into the effect of drugs against pain in the GI tract. Hence, the multimodal methods undoubtedly represents a major step forward in the future characterization and treatment of patients with various diseases of the gut. PMID:16688791

  18. Highly sensitive bending sensor based on multimode-multimode-coreoffset fiber structure

    NASA Astrophysics Data System (ADS)

    Qi, Yanhui; Ma, Lin; Sun, Jiang; Kang, Zexin; Bai, Yunlong; Jian, Shuisheng

    2015-12-01

    In this paper, we present a simple fiber optic bending sensor based on the multimode-multimode structure combining with the core-offset fiber structure. The multimode-multimode structure is composed of no core fiber (NCF) with hundreds of micrometers in length as a micro-lens for mode conversion, and single mode fiber (SMF) which can be seen as a section of special multimode fiber (MMF) when considered the cladding modes. The transmission spectrum in the experiment agrees well with the numerical model. The sensitivity of the structure can be achieved as high as 11.104 nm/m-1 in the measuring range. Meanwhile, the sensitivity of the neighboring resonance wavelength around 1546 nm exhibits approximately the same sensitivity which is 10.579 nm/m-1. Besides, the strain sensitivity is about -0.927 pm/με within the measuring strain range.

  19. Multimodal analgesia and regional anaesthesia.

    PubMed

    Tornero Tornero, C; Fernández Rodríguez, L E; Orduña Valls, J

    Multimodal analgesia provides quality analgesia, with fewer side effects due to the use of combined analgesics or analgesic techniques. Regional anaesthesia plays a fundamental role in achieving this goal. The different techniques of regional anaesthesia that include both peripheral and central blocks in either a single dose or in continuous infusion help to modulate the nociceptive stimuli that access the central level. The emergence of the ultrasound as an effective system to perform regional anaesthesia techniques has allowed the development of new regional anaesthesia techniques that formerly could not be carried out since only neurostimulation or skin references were used. It is essential to take into account that even with effective blocking it is advisable to associate other drugs by other routes, in this way we will be able to reduce the required doses individually and attempt to achieve a synergistic, not purely additive, effect. Copyright © 2017 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. Miniature multimode monolithic flextensional transducers.

    PubMed

    Hladky-Hennion, Anne-Christine; Uzgur, A Erman; Markley, Douglas C; Safari, Ahmad; Cochran, Joe K; Newnham, Robert E

    2007-10-01

    Traditional flextensional transducers classified in seven groups based on their designs have been used extensively in 1-100 kHz range for mine hunting, fish finding, oil explorations, and biomedical applications. In this study, a new family of small, low cost underwater, and biomedical transducers has been developed. After the fabrication of transducers, finite-elements analysis (FEA) was used extensively in order to optimize these miniature versions of high-power, low-frequency flextensional transducer designs to achieve broad bandwidth for both transmitting and receiving, engineered vibration modes, and optimized acoustic directivity patterns. Transducer topologies with various shapes, cross sections, and symmetries can be fabricated through high-volume, low-cost ceramic and metal extrusion processes. Miniaturized transducers posses resonance frequencies in the range of above 1 MHz to below 10 kHz. Symmetry and design of the transducer, polling patterns, driving and receiving electrode geometries, and driving conditions have a strong effect on the vibration modes, resonance frequencies, and radiation patterns. This paper is devoted to small, multimode flextensional transducers with active shells, which combine the advantages of small size and low-cost manufacturing with control of the shape of the acoustic radiation/receive pattern. The performance of the transducers is emphasized.

  1. Multimodality Instrument for Tissue Characterization

    NASA Technical Reports Server (NTRS)

    Mah, Robert W. (Inventor); Andrews, Russell J. (Inventor)

    2000-01-01

    A system with multimodality instrument for tissue identification includes a computer-controlled motor driven heuristic probe with a multisensory tip is discussed. For neurosurgical applications, the instrument is mounted on a stereotactic frame for the probe to penetrate the brain in a precisely controlled fashion. The resistance of the brain tissue being penetrated is continually monitored by a miniaturized strain gauge attached to the probe tip. Other modality sensors may be mounted near the probe tip to provide real-time tissue characterizations and the ability to detect the proximity of blood vessels, thus eliminating errors normally associated with registration of pre-operative scans, tissue swelling, elastic tissue deformation, human judgement, etc., and rendering surgical procedures safer, more accurate, and efficient. A neural network, program adaptively learns the information on resistance and other characteristic features of normal brain tissue during the surgery and provides near real-time modeling. A fuzzy logic interface to the neural network program incorporates expert medical knowledge in the learning process. Identification of abnormal brain tissue is determined by the detection of change and comparison with previously learned models of abnormal brain tissues. The operation of the instrument is controlled through a user friendly graphical interface. Patient data is presented in a 3D stereographics display. Acoustic feedback of selected information may optionally be provided. Upon detection of the close proximity to blood vessels or abnormal brain tissue, the computer-controlled motor immediately stops probe penetration.

  2. Multimodal Phantom of Liver Tissue

    PubMed Central

    Chmarra, Magdalena K.; Hansen, Rune; Mårvik, Ronald; Langø, Thomas

    2013-01-01

    Medical imaging plays an important role in patients' care and is continuously being used in managing health and disease. To obtain the maximum benefit from this rapidly developing technology, further research is needed. Ideally, this research should be done in a patient-safe and environment-friendly manner; for example, on phantoms. The goal of this work was to develop a protocol and manufacture a multimodal liver phantom that is suitable for ultrasound, computed tomography, and magnetic resonance imaging modalities. The proposed phantom consists of three types of mimicked soft tissues: liver parenchyma, tumors, and portal veins, that are made of six ingredients: candle gel, sephadex®, agarose, glycerol, distilled water, and silicone string. The entire procedure is advantageous, since preparation of the phantom is simple, rather cost-effective, and reasonably quick – it takes around 2 days. Besides, most of the phantom's parts can be reused to manufacture a new phantom. Comparison of ultrasound images of real patient's liver and the developed phantom shows that the phantom's liver tissue and its structures are well simulated. PMID:23691165

  3. Multimodality Management of Trigeminal Schwannomas.

    PubMed

    Niranjan, Ajay; Barnett, Samuel; Anand, Vijay; Agazzi, Siviero

    2016-08-01

    Patients presenting with trigeminal schwannomas require multimodality management by a skull base surgical team that can offer expertise in both transcranial and transnasal approaches as well as radiosurgical and microsurgical strategies. Improvement in neurologic symptoms, preservation of cranial nerve function, and control of mass effect are the primary goals of management for trigeminal schwannomas. Complete surgical resection is the treatment of choice but may not be possible in all cases. Radiosurgery is an option as primary management for small- to moderate-sized tumors and can be used for postoperative residuals or recurrences. Planned surgical resection followed by SRS for residual tumor is an effective option for larger trigeminal schwannomas. The endoscopic resection is an excellent approach for patients with an extradural tumor or tumors isolated to the Meckel cave. A detailed analysis of a tumor and its surroundings based on high-quality imaging can help better estimate the expected outcome from each treatment. An expert skull base team should be able to provide precise counseling for each patient's situation for selecting the best option.

  4. Multimodal imaging measures predict rearrest

    PubMed Central

    Steele, Vaughn R.; Claus, Eric D.; Aharoni, Eyal; Vincent, Gina M.; Calhoun, Vince D.; Kiehl, Kent A.

    2015-01-01

    Rearrest has been predicted by hemodynamic activity in the anterior cingulate cortex (ACC) during error-processing (Aharoni et al., 2013). Here, we evaluate the predictive power after adding an additional imaging modality in a subsample of 45 incarcerated males from Aharoni et al. (2013). Event-related potentials (ERPs) and hemodynamic activity were collected during a Go/NoGo response inhibition task. Neural measures of error-processing were obtained from the ACC and two ERP components, the error-related negativity (ERN/Ne) and the error positivity (Pe). Measures from the Pe and ACC differentiated individuals who were and were not subsequently rearrested. Cox regression, logistic regression, and support vector machine (SVM) neuroprediction models were calculated. Each of these models proved successful in predicting rearrest and SVM provided the strongest results. Multimodal neuroprediction SVM models with out of sample cross-validating accurately predicted rearrest (83.33%). Offenders with increased Pe amplitude and decreased ACC activation, suggesting abnormal error-processing, were at greatest risk of rearrest. PMID:26283947

  5. Multimodal Behavior Therapy: Case Study of a High School Student.

    ERIC Educational Resources Information Center

    Seligman, Linda

    1981-01-01

    A case study of a high school student concerned with weight problems illustrates multimodal behavior therapy and its use in a high school setting. Multimodal therapy allows the school counselor to maximize referral sources while emphasizing growth and actualization. (JAC)

  6. Multimode siloxane polymer components for optical interconnects

    NASA Astrophysics Data System (ADS)

    Bamiedakis, Nikolaos; Beals, Joseph, IV; Penty, Richard V.; White, Ian H.; DeGroot, Jon v., Jr.; Clapp, Terry V.; De Shazer, David

    2009-02-01

    This paper presents an overview of multimode waveguides and waveguide components formed from siloxane polymer materials which are suitable for use in optical interconnection applications. The components can be cost-effectively integrated onto conventional PCBs and offer increased functionality in optical transmission. The multimode waveguides exhibit low loss (0.04 dB/cm at 850 nm) and low crosstalk (< -30 dB) performance, large alignment tolerances and negligible mode mixing for short waveguide lengths. Error-free data transmission at 10 Gb/s over 1.4 m long waveguides has been successfully demonstrated. Waveguide crossings exhibit very low excess losses, below 0.01 dB/crossing, and excellent crosstalk performance. Low loss is obtained for waveguide bends with radii of curvature larger than 8 mm and 6 mm for 90° and S-shaped bends respectively. High-uniformity splitting is achieved with multimode Y-splitters even in the presence of input misalignments. Y-combiners are shown to benefit from the multimode nature of the waveguides allowing low loss combining (4 dB for an 8×1 device). A large range of power splitting ratios between 30% and 75% is achieved with multimode coupler devices. Examples of system applications benefiting from the use of these components are briefly presented including a terabit capacity optical backplane, a radio-over-fibre multicasting system and a SCM passive optical network.

  7. Multimodality image guidance system integrating X-ray fluoroscopy and ultrasound image streams with electromagnetic tracking

    NASA Astrophysics Data System (ADS)

    Gutiérrez, Luis F.; Shechter, Guy; Stanton, Douglas; Dalal, Sandeep; Elgort, Daniel; Manzke, Robert; Chan, Raymond C.; Zagorchev, Lyubomir

    2007-03-01

    This work presents an integrated system for multimodality image guidance of minimally invasive medical procedures. This software and hardware system offers real-time integration and registration of multiple image streams with localization data from navigation systems. All system components communicate over a local area Ethernet network, enabling rapid and flexible deployment configurations. As a representative configuration, we use X-ray fluoroscopy (XF) and ultrasound (US) imaging. The XF imaging system serves as the world coordinate system, with gantry geometry derived from the imaging system, and patient table position tracked with a custom-built measurement device using linear encoders. An electromagnetic (EM) tracking system is registered to the XF space using a custom imaging phantom that is also tracked by the EM system. The RMS fiducial registration error for the EM to X-ray registration was 2.19 mm, and the RMS target registration error measured with an EM-tracked catheter was 8.81 mm. The US image stream is subsequently registered to the XF coordinate system using EM tracking of the probe, following a calibration of the US image within the EM coordinate system. We present qualitative results of the system in operation, demonstrating the integration of live ultrasound imaging spatially registered to X-ray fluoroscopy with catheter localization using electromagnetic tracking.

  8. How Multimodality Works in Mathematical Activity: Young Children Graphing Motion

    ERIC Educational Resources Information Center

    Ferrara, Francesca

    2014-01-01

    This paper aims to contribute to discussions on the multimodal nature of cognition through an elaboration of the ways multimodal aspects of thinking are exploited by learners doing mathematics. Moving beyond the fact "that" multimodality occurs, this paper focuses on "how" it occurs, with particular attention drawn to the…

  9. "Filming in Progress": New Spaces for Multimodal Designing

    ERIC Educational Resources Information Center

    Mills, Kathy A.

    2010-01-01

    Global trends call for new research to investigate multimodal designing mediated by new technologies and the implications for classroom spaces. This article addresses the relationship between new technologies, students' multimodal designing, and the social production of classroom spaces. Multimodal semiotics and sociological principles are applied…

  10. "Filming in Progress": New Spaces for Multimodal Designing

    ERIC Educational Resources Information Center

    Mills, Kathy A.

    2010-01-01

    Global trends call for new research to investigate multimodal designing mediated by new technologies and the implications for classroom spaces. This article addresses the relationship between new technologies, students' multimodal designing, and the social production of classroom spaces. Multimodal semiotics and sociological principles are applied…

  11. How Multimodality Works in Mathematical Activity: Young Children Graphing Motion

    ERIC Educational Resources Information Center

    Ferrara, Francesca

    2014-01-01

    This paper aims to contribute to discussions on the multimodal nature of cognition through an elaboration of the ways multimodal aspects of thinking are exploited by learners doing mathematics. Moving beyond the fact "that" multimodality occurs, this paper focuses on "how" it occurs, with particular attention drawn to the…

  12. New Times for Multimodality? Confronting the Accountability Culture

    ERIC Educational Resources Information Center

    Siegel, Marjorie

    2012-01-01

    As new times become hard times, there may be little time for multimodality in school unless educators confront the accountability culture. This commentary reviews the arguments for multimodal transformations of school literacy curricula and explores the potential of reflective talk about multimodal meaning-making as an assessment practice. Talking…

  13. Video genre classification using multimodal features

    NASA Astrophysics Data System (ADS)

    Jin, Sung Ho; Bae, Tae Meon; Choo, Jin Ho; Ro, Yong Man

    2003-12-01

    We propose a video genre classification method using multimodal features. The proposed method is applied for the preprocessing of automatic video summarization or the retrieval and classification of broadcasting video contents. Through a statistical analysis of low-level and middle-level audio-visual features in video, the proposed method can achieve good performance in classifying several broadcasting genres such as cartoon, drama, music video, news, and sports. In this paper, we adopt MPEG-7 audio-visual descriptors as multimodal features of video contents and evaluate the performance of the classification by feeding the features into a decision tree-based classifier which is trained by CART. The experimental results show that the proposed method can recognize several broadcasting video genres with a high accuracy and the classification performance with multimodal features is superior to the one with unimodal features in the genre classification.

  14. River multimodal scenario for rehabilitation robotics.

    PubMed

    Munih, Marko; Novak, Domen; Milavec, Maja; Ziherl, Jaka; Olenšek, Andrej; Mihelj, Matjaž

    2011-01-01

    This paper presents the novel "River" multimodal rehabilitation robotics scenario that includes video, audio and haptic modalities. Elements contributing to intrinsic motivation are carefully joined in the three modalities to increase motivation of the user. The user first needs to perform a motor action, then receives a cognitive challenge that is solved with adequate motor activity. Audio includes environmental sounds, music and spoken instructions or encouraging statements. Sounds and music were classified according to the arousal-valence space. The haptic modality can provide catching, grasping, tunnel or adaptive assistance, all depending on the user's needs. The scenario was evaluated in 16 stroke users, who responded to it favourably according to the Intrinsic Motivation Inventory questionnaire. Additionally, the river multimodal environment seems to elicit higher motivation than a simpler apple pick-and-place multimodal task. © 2011 IEEE

  15. [Multimodal pain therapy: principles and indications].

    PubMed

    Arnold, B; Brinkschmidt, T; Casser, H-R; Gralow, I; Irnich, D; Klimczyk, K; Müller, G; Nagel, B; Pfingsten, M; Schiltenwolf, M; Sittl, R; Söllner, W

    2009-04-01

    Multimodal pain therapy describes an integrated multidisciplinary treatment in small groups with a closely coordinated therapeutical approach. Somatic and psychotherapeutic procedures cooperate with physical and psychological training programs. For chronic pain syndromes with complex somatic, psychological and social consequences, a therapeutic intensity of at least 100 hours is recommended. Under these conditions multimodal pain therapy has proven to be more effective than other kinds of treatment. If monodisciplinary and/or outpatient therapies fail, health insurance holders have a legitimate claim to this form of therapy.Medical indications are given for patients with chronic pain syndromes, but also if there is an elevated risk of chronic pain in the early stadium of the disease and aiming at delaying the process of chronification. Relative contraindications are a lack of motivation for behavioural change, severe mental disorders or psychopathologies and addiction problems. The availability of multimodal pain treatment centers in Germany is currently insufficient.

  16. Multimodal imaging of cutaneous wound tissue

    NASA Astrophysics Data System (ADS)

    Zhang, Shiwu; Gnyawali, Surya; Huang, Jiwei; Ren, Wenqi; Gordillo, Gayle; Sen, Chandan K.; Xu, Ronald

    2015-01-01

    Quantitative assessment of wound tissue ischemia, perfusion, and inflammation provides critical information for appropriate detection, staging, and treatment of chronic wounds. However, few methods are available for simultaneous assessment of these tissue parameters in a noninvasive and quantitative fashion. We integrated hyperspectral, laser speckle, and thermographic imaging modalities in a single-experimental setup for multimodal assessment of tissue oxygenation, perfusion, and inflammation characteristics. Algorithms were developed for appropriate coregistration between wound images acquired by different imaging modalities at different times. The multimodal wound imaging system was validated in an occlusion experiment, where oxygenation and perfusion maps of a healthy subject's upper extremity were continuously monitored during a postocclusive reactive hyperemia procedure and compared with standard measurements. The system was also tested in a clinical trial where a wound of three millimeters in diameter was introduced on a healthy subject's lower extremity and the healing process was continuously monitored. Our in vivo experiments demonstrated the clinical feasibility of multimodal cutaneous wound imaging.

  17. Instrumentation challenges in multi-modality imaging

    NASA Astrophysics Data System (ADS)

    Brasse, D.; Boisson, F.

    2016-02-01

    Based on different physical principles, imaging procedures currently used in both clinical and preclinical applications present different performance that allow researchers to achieve a large number of studies. However, the relevance of obtaining a maximum of information relating to the same subject is undeniable. The last two decades have thus seen the advent of a full-fledged research axis, the multimodal in vivo imaging. Whether from an instrumentation point of view, for medical research or the development of new probes, all these research works illustrate the growing interest of the scientific community for multimodal imaging, which can be approached with different backgrounds and perspectives from engineers to end-users point of views. In the present review, we discuss the multimodal imaging concept, which focuses not only on PET/CT and PET/MRI instrumentation but also on recent investigations of what could become a possible future in the field.

  18. An Overview of Multimodal Neuroimaging Using Nanoprobes

    PubMed Central

    Sridhar, Sriram; Mishra, Sachin; Gulyás, Miklós; Padmanabhan, Parasuraman; Gulyás, Balázs

    2017-01-01

    Nanomaterials have gained tremendous significance as contrast agents for both anatomical and functional preclinical bio-imaging. Contrary to conventional medical practices, molecular imaging plays an important role in exploring the affected cells, thus providing precision medical solutions. It has been observed that incorporating nanoprobes improves the overall efficacy of the diagnosis and treatment processes. These nano-agents and tracers are therefore often incorporated into preclinical therapeutic and diagnostic applications. Multimodal imaging approaches are well equipped with nanoprobes to explore neurological disorders, as they can display more than one type of characteristic in molecular imaging. Multimodal imaging systems are explored by researchers as they can provide both anatomical and functional details of tumors and affected tissues. In this review, we present the state-of-the-art research concerning multimodal imaging systems and nanoprobes for neuroimaging applications. PMID:28157157

  19. Fiber optic multimode displacement sensor

    NASA Astrophysics Data System (ADS)

    Fisher, Karl A.; Jarzynski, Jacek

    1996-04-01

    An underwater Optical Motion Sensor (OMS) based on a design first presented by W. B. Spillman, Schlieren multimode fiber-optic hydrophone, Applied Physics Letters 37(2), 15 July 1980, p. 145-146 is described. The displacement sensor uses the same acoustooptical intensity modulation mechanism as Spillman, however the sensing mechanism is isolated from the ambient fluid environment by a small cylindrical aluminum enclosure (1″ OD×3/4″). The enclosure contains an inertial mass and the fiber collimators. The inertial mass is suspended in the center of the enclosure by three small wires rigidly mounted to the walls. The mass and wires act as a cantilever beam system with a mechanical resonance near 100 Hz. The transduction mechanism consists of two opposed optical gratings aligned and positioned between the fiber collimators. One grating is mounted on the inertial mass while the other is mounted on the lower end cap of the enclosure. Relative motion between the gratings causes a modulation of the light transmitted through the gratings. The modulated beam is focused onto a photodetector and converted to electric current. The frequency response is flat from 200 Hz-9 kHz with a minimum detectable displacement of 0.002 A and the dynamic range is 136 dB. The small size and light weight give the sensor an effective density of 1.08 g/cm3 making it almost neutrally buoyant in water. This in conjunction with the performance characteristics make this sensor suitable for use in acoustical sensing applications.

  20. Multimodality instrument for tissue characterization

    NASA Technical Reports Server (NTRS)

    Mah, Robert W. (Inventor); Andrews, Russell J. (Inventor)

    2004-01-01

    A system with multimodality instrument for tissue identification includes a computer-controlled motor driven heuristic probe with a multisensory tip. For neurosurgical applications, the instrument is mounted on a stereotactic frame for the probe to penetrate the brain in a precisely controlled fashion. The resistance of the brain tissue being penetrated is continually monitored by a miniaturized strain gauge attached to the probe tip. Other modality sensors may be mounted near the probe tip to provide real-time tissue characterizations and the ability to detect the proximity of blood vessels, thus eliminating errors normally associated with registration of pre-operative scans, tissue swelling, elastic tissue deformation, human judgement, etc., and rendering surgical procedures safer, more accurate, and efficient. A neural network program adaptively learns the information on resistance and other characteristic features of normal brain tissue during the surgery and provides near real-time modeling. A fuzzy logic interface to the neural network program incorporates expert medical knowledge in the learning process. Identification of abnormal brain tissue is determined by the detection of change and comparison with previously learned models of abnormal brain tissues. The operation of the instrument is controlled through a user friendly graphical interface. Patient data is presented in a 3D stereographics display. Acoustic feedback of selected information may optionally be provided. Upon detection of the close proximity to blood vessels or abnormal brain tissue, the computer-controlled motor immediately stops probe penetration. The use of this system will make surgical procedures safer, more accurate, and more efficient. Other applications of this system include the detection, prognosis and treatment of breast cancer, prostate cancer, spinal diseases, and use in general exploratory surgery.

  1. MULTIMODALITY TREATMENT OF PEDIATRIC ESTHESIONEUROBLASTOMA

    PubMed Central

    Venkatramani, Rajkumar; Pan, Hubert; Furman, Wayne L.; Marron, Jonathan M.; Haduong, Josephine; Friedrich-Medina, Paola; Mahajan, Anita; Bavle, Abhishek; Wu, Hao; Chintagumpala, Murali

    2016-01-01

    Background Esthesioneuroblastoma (ENB) is a rare cancer of the nasal cavity in children. Radical surgery followed by post-operative radiation is considered the standard of care in adults. A similar approach in children can lead to significant long-term morbidity. Procedure A retrospective multi-institutional review of patients <21 years of age diagnosed with ENB between 1990 and 2014 was performed. Clinical features, treatment and outcome were obtained from the medical records. Results Twenty-four patients were identified; median age at diagnosis was 14 years (range 0.6 – 20 years). The majority (75%) were female. Headache was the most common presenting symptom, followed by nasal obstruction and epistaxis. Eight patients had Kadish stage B tumors and 16 had Kadish Stage C. Nine patients had metastatic disease. Gross total resection was achieved at diagnosis in eight patients and after neoadjuvant chemotherapy in four patients. Twenty-one patients received radiation therapy (45 Gy – 68.4 Gy). Thirteen patients received neoadjuvant chemotherapy with 84% objective response rate. Seven patients experienced disease progression or relapse; five in central nervous system, one local and one in cervical lymph node. Fifteen patients were alive at last follow-up. The 5-year disease free survival and overall survival were 74% and 73% respectively. Late effects were observed in 78% of long-term survivors. Four patients developed subsequent malignant neoplasms. Conclusions Pediatric ENB is a chemosensitive disease. Pre-operative chemotherapy based multimodal approach should be used in patients with advanced stage disease. Radiation therapy is effective for local control but lower doses should be considered in children. PMID:26514449

  2. Temperature insensitive single-mode-multimode-single-mode fiber optic structures with two multimode fibers in series.

    PubMed

    Tripathi, Saurabh Mani; Kumar, Arun; Kumar, Manoj; Bock, Wojtek J

    2014-06-01

    We propose and demonstrate a temperature insensitive single-mode-multimode-single-mode fiber optic structure consisting of two in-series multimode fibers of appropriate lengths and of opposite temperature sensitivities. A simple approximate expression to estimate the required length ratio of the multimode fiber sections has also been derived whose prediction is found in good agreement with the experiment. The study should be useful in realizing various fiber optic devices based on multimode interference with zero temperature cross sensitivity.

  3. Tunable multimode-interference bandpass fiber filter.

    PubMed

    Antonio-Lopez, J E; Castillo-Guzman, A; May-Arrioja, D A; Selvas-Aguilar, R; Likamwa, P

    2010-02-01

    We report on a wavelength-tunable filter based on multimode interference (MMI) effects. A typical MMI filter consists of a multimode fiber (MMF) spliced between two single-mode fibers (SMF). The peak wavelength response of the filter exhibits a linear dependence when the length of the MMF is modified. Therefore a capillary tube filled with refractive-index-matching liquid is used to effectively increase the length of the MMF, and thus wavelength tuning is achieved. Using this filter a ring-based tunable erbium-doped fiber laser is demonstrated with a tunability of 30 nm, covering the full C-band.

  4. Multimodal MRI segmentation of ischemic stroke lesions

    PubMed Central

    Kabir, Yacine; Dojat, Michel; Scherrer, Benoît; Forbes, Florence; Garbay, Catherine

    2007-01-01

    The problem addressed in this paper is the automatic segmentation of stroke lesions on MR multi-sequences. Lesions enhance differently depending on the MR modality and there is an obvious gain in trying to account for various sources of information in a single procedure. To this aim, we propose a multimodal Markov random field model which includes all MR modalities simultaneously. The results of the multimodal method proposed are compared with those obtained with a mono-dimensional segmentation applied on each MRI sequence separately. We constructed an Atlas of blood supply territories to help clinicians in the determination of stroke subtypes and potential functional deficit. PMID:18002276

  5. Multimodal analysis of startle type responses.

    PubMed

    Ćosić, Krešimir; Popović, Siniša; Kukolja, Davor; Dropuljić, Branimir; Ivanec, Dragutin; Tonković, Mirjana

    2016-06-01

    This article presents a multimodal analysis of startle type responses using a variety of physiological, facial, and speech features. These multimodal components of the startle type response reflect complex brain-body reactions to a sudden and intense stimulus. Additionally, the proposed multimodal evaluation of reflexive and emotional reactions associated with the startle eliciting stimuli and underlying neural networks and pathways could be applied in diagnostics of different psychiatric and neurological diseases. Different startle type stimuli can be compared in the strength of their elicitation of startle responses, i.e. their potential to activate stress-related neural pathways, underlying biomarkers and corresponding behavioral reactions. An innovative method for measuring startle type responses using multimodal stimuli and multimodal feature analysis has been introduced. Individual's multimodal reflexive and emotional expressions during startle type elicitation have been assessed by corresponding physiological, speech and facial features on ten female students of psychology. Different startle eliciting stimuli like noise and airblast probes, as well as a variety of visual and auditory stimuli of different valence and arousal levels, based on International Affective Picture System (IAPS) images and/or sounds from International Affective Digitized Sounds (IADS) database, have been designed and tested. Combined together into more complex startle type stimuli, such composite stimuli can potentiate the evoked response of underlying neural networks, and corresponding neurotransmitters and neuromodulators as well; this is referred to as increased power of response elicitation. The intensity and magnitude of multimodal responses to selected startle type stimuli have been analyzed using effect sizes and medians of dominant multimodal features, i.e. skin conductance, eye blink, head movement, speech fundamental frequency and energy. The significance of the observed

  6. Chemistry of porous coordination polymers having multimodal nanospace and their multimodal functionality.

    PubMed

    Seo, Joobeom; Sakamoto, Hirotoshi; Matsuda, Ryotaro; Kitagawa, Susumu

    2010-01-01

    Remarkable advances in the recent development of porous coordination polymers (PCPs) or metal organic frameworks (MOFs) have paved the way toward functional chemistry having potential application such as molecular storage, separation, and catalysis. Moreover flexible PCPs, which are structurally transformable depending upon guest molecules adsorption/desorption, have received much attention because they provide unique properties, dissimilar to those of zeolites. PCPs can be categorized into structurally monomodal and multimodal classes. Monomodal PCPs possess single uniform pores in the framework. In contrast, multimodal PCPs have more than two types of pores in the framework. Interpenetrated PCPs can possess more than two types of pores with different sizes and shapes in the same framework depending on relative position of individual motifs, resulting in multimodal PCPs. Moreover, interpenetrated PCPs have several advantages, such as high thermal stability, flexibility, and ultramicropore for effective adsorption. In this review, chemistry of PCPs based on monomodal and multimodal PCPs are summarized and discussed.

  7. Connecting multimodality in human communication.

    PubMed

    Regenbogen, Christina; Habel, Ute; Kellermann, Thilo

    2013-01-01

    DCM analysis instead showed a pronounced top-down control. Remarkably, all connections from the dmPFC to the three other regions were modulated by the experimental conditions. This observation is in line with the presumed role of the dmPFC in the allocation of attention. In contrary, all incoming connections to the AG were modulated, indicating its key role in integrating multimodal information and supporting comprehension. Notably, the input from the FFG to the AG was enhanced when facial expressions conveyed emotional information. These findings serve as preliminary results in understanding network dynamics in human emotional communication and empathy.

  8. Connecting multimodality in human communication

    PubMed Central

    Regenbogen, Christina; Habel, Ute; Kellermann, Thilo

    2013-01-01

    DCM analysis instead showed a pronounced top-down control. Remarkably, all connections from the dmPFC to the three other regions were modulated by the experimental conditions. This observation is in line with the presumed role of the dmPFC in the allocation of attention. In contrary, all incoming connections to the AG were modulated, indicating its key role in integrating multimodal information and supporting comprehension. Notably, the input from the FFG to the AG was enhanced when facial expressions conveyed emotional information. These findings serve as preliminary results in understanding network dynamics in human emotional communication and empathy. PMID:24265613

  9. Enriching and Assessing Young Children's Multimodal Storytelling

    ERIC Educational Resources Information Center

    Wessel-Powell, Christy; Kargin, Tolga; Wohlwend, Karen E.

    2016-01-01

    This article provides primary teachers with assessment tools and curricular examples to expand writers' workshop by adding a multimodal storytelling unit on drama and filmmaking, allowing students to create engaging off-the-page stories through films and play performances that enrich writing. Too often, children's literacy abilities are assessed…

  10. Reconceptualising Poetry as a Multimodal Genre

    ERIC Educational Resources Information Center

    Newfield, Denise; D'abdon, Raphael

    2015-01-01

    This conceptual article theorises the role of poetry in English classrooms from a multimodal perspective. It discusses the gap between the practices of poetry inside and outside South African schools, particularly where English is taught as an additional language (EAL). The former is shown to be monomodal and prescriptive, while the latter is…

  11. A multimodal approach to elimination of stuttering.

    PubMed

    Beaty, D T

    1980-02-01

    Various approaches have been used in the treatment of stuttering. However, none of these approaches have been systematically incorporated via a multifaceted treatment program for the elimination of this disorder. The following case of a 15-yr.-old stutterer is presented to illustrate Lazarus' Multimodal Behavior Therapy Model, which is proposed to integrate various procedures whose singular effectiveness has been demonstrated.

  12. Multimodal Design, Learning and Cultures of Recognition

    ERIC Educational Resources Information Center

    Kress, Gunther; Selander, Staffan

    2012-01-01

    In this article, a design-oriented, multimodal understanding of learning will be outlined. There seems to be a need for a new conceptualisation of learning in an era characterised by an increasing virtual space, blended media and new communicative patterns. This means a broader understanding of learning, and a theoretical understanding of…

  13. Imagining the Possibilities in Multimodal Curriculum Design

    ERIC Educational Resources Information Center

    Albers, Peggy

    2006-01-01

    Evolution of the "old page", or written hardcopy texts, to the "new" (Kress, 2003), or electronic page, means that today's learners have experience with reading a variety of texts. Image, music, and electronic inscription (font, style, flash, and so on) are features of multimodal texts that many learners prefer to read and create. With the screen…

  14. Academic Knowledge Construction and Multimodal Curriculum Development

    ERIC Educational Resources Information Center

    Loveless, Douglas J., Ed.; Griffith, Bryant, Ed.; Bérci, Margaret E., Ed.; Ortlieb, Evan, Ed.; Sullivan, Pamela, Ed.

    2014-01-01

    While incorporating digital technologies into the classroom has offered new ways of teaching and learning into educational processes, it is essential to take a look at how the digital shift impacts teachers, school administration, and curriculum development. "Academic Knowledge Construction and Multimodal Curriculum Development" presents…

  15. Love that Book: Multimodal Response to Literature

    ERIC Educational Resources Information Center

    Dalton, Bridget; Grisham, Dana L.

    2013-01-01

    Composing with different modes--image, sound, video and the written word--to respond to and analyze literary and informational text helps students develop as readers and digital communicators. This article showcases five multimodal strategies for engaging children in rich literature-based learning using digital tools and Internet resources.

  16. The Arts, New Literacies, and Multimodality

    ERIC Educational Resources Information Center

    Albers, Peggy; Harste, Jerome C.

    2007-01-01

    The arts, multimodality, and new literacies studies, each with its own distinct principles, together can redefine literacy and what constitutes being literate. To recognize the roles that each of these fields plays in literacy necessitates a cultural shift in reading, interpreting, creating, and responding to a range of multimedia messages. The…

  17. Automatic Rejection Of Multimode Laser Pulses

    NASA Technical Reports Server (NTRS)

    Tratt, David M.; Menzies, Robert T.; Esproles, Carlos

    1991-01-01

    Characteristic modulation detected, enabling rejection of multimode signals. Monitoring circuit senses multiple longitudinal mode oscillation of transversely excited, atmospheric-pressure (TEA) CO2 laser. Facility developed for inclusion into coherent detection laser radar (LIDAR) system. However, circuit described of use in any experiment where desireable to record data only when laser operates in single longitudinal mode.

  18. Re-Imagining Pedagogies for Multimodal Selves

    ERIC Educational Resources Information Center

    Vasudevan, Lalitha

    2011-01-01

    In this chapter, the author rethinks literacy education and identity in the 21st century by engaging with the concept of multimodal selves. This conceptualization resonates with an understanding of identity as performed (Blackburn, 2005) wherein the ways of enacting oneself with and within a space encompass the intentional and unintentional…

  19. Imagining the Possibilities in Multimodal Curriculum Design

    ERIC Educational Resources Information Center

    Albers, Peggy

    2006-01-01

    Evolution of the "old page", or written hardcopy texts, to the "new" (Kress, 2003), or electronic page, means that today's learners have experience with reading a variety of texts. Image, music, and electronic inscription (font, style, flash, and so on) are features of multimodal texts that many learners prefer to read and create. With the screen…

  20. Researching Multimodal Texts: Applying a Dynamic Model.

    ERIC Educational Resources Information Center

    Clancy, Susan; Lowrie, Tom

    The arrival of the digital age requires new approaches to understand the literacies used in making meanings from multimodal communications, and a rethinking of the ways in which research into these areas can be used to support learners in the 21st century. This presentation examines the range of literacies children have developed and used to make…

  1. Nanoparticles in Higher-Order Multimodal Imaging

    NASA Astrophysics Data System (ADS)

    Rieffel, James Ki

    Imaging procedures are a cornerstone in our current medical infrastructure. In everything from screening, diagnostics, and treatment, medical imaging is perhaps our greatest tool in evaluating individual health. Recently, there has been tremendous increase in the development of multimodal systems that combine the strengths of complimentary imaging technologies to overcome their independent weaknesses. Clinically, this has manifested in the virtually universal manufacture of combined PET-CT scanners. With this push toward more integrated imaging, new contrast agents with multimodal functionality are needed. Nanoparticle-based systems are ideal candidates based on their unique size, properties, and diversity. In chapter 1, an extensive background on recent multimodal imaging agents capable of enhancing signal or contrast in three or more modalities is presented. Chapter 2 discusses the development and characterization of a nanoparticulate probe with hexamodal imaging functionality. It is my hope that the information contained in this thesis will demonstrate the many benefits of nanoparticles in multimodal imaging, and provide insight into the potential of fully integrated imaging.

  2. Multimode waveguide speckle patterns for compressive sensing.

    PubMed

    Valley, George C; Sefler, George A; Justin Shaw, T

    2016-06-01

    Compressive sensing (CS) of sparse gigahertz-band RF signals using microwave photonics may achieve better performances with smaller size, weight, and power than electronic CS or conventional Nyquist rate sampling. The critical element in a CS system is the device that produces the CS measurement matrix (MM). We show that passive speckle patterns in multimode waveguides potentially provide excellent MMs for CS. We measure and calculate the MM for a multimode fiber and perform simulations using this MM in a CS system. We show that the speckle MM exhibits the sharp phase transition and coherence properties needed for CS and that these properties are similar to those of a sub-Gaussian MM with the same mean and standard deviation. We calculate the MM for a multimode planar waveguide and find dimensions of the planar guide that give a speckle MM with a performance similar to that of the multimode fiber. The CS simulations show that all measured and calculated speckle MMs exhibit a robust performance with equal amplitude signals that are sparse in time, in frequency, and in wavelets (Haar wavelet transform). The planar waveguide results indicate a path to a microwave photonic integrated circuit for measuring sparse gigahertz-band RF signals using CS.

  3. Effects of Webcams on Multimodal Interactive Learning

    ERIC Educational Resources Information Center

    Codreanu, Tatiana; Celik, Christelle Combe

    2013-01-01

    This paper describes the multimodal pedagogical communication of two groups of online teachers; trainee tutors (second year students of the Master of Arts in Teaching French as a Foreign Language at the University Lumiere-Lyon 2) and experienced teachers based in different locations (France, Spain and Finland). They all taught French as a Foreign…

  4. Cross mode modulation in multimode fibers.

    PubMed

    Kroushkov, Dimitar I; Rademacher, Georg; Petermann, Klaus

    2013-05-15

    We show that Kerr nonlinearity induced intermodal power transfer in a particular mode group of a multimode fiber can be formulated by the same type of equation used to describe the effect of cross polarization modulation in single-mode fibers.

  5. Exostosis Bursata – Multimodality Imaging Approach

    PubMed Central

    Sharma, Praveen; Rege, Rujuta; Seena, CR; Rajesh, Saveetha

    2016-01-01

    Osteochondromas or exostosis are common benign bone tumours, commonly arising from the metaphyseal region of long bones (femur, humerus, tibia). Osteochondroma of the scapula are rare and cause mechanical irritation leading to bursal formation. We hereby report a case of 30-year-old man who presented with painful chest wall swelling and its multimodality approach to establish the diagnosis. PMID:27790547

  6. Effects of Webcams on Multimodal Interactive Learning

    ERIC Educational Resources Information Center

    Codreanu, Tatiana; Celik, Christelle Combe

    2013-01-01

    This paper describes the multimodal pedagogical communication of two groups of online teachers; trainee tutors (second year students of the Master of Arts in Teaching French as a Foreign Language at the University Lumiere-Lyon 2) and experienced teachers based in different locations (France, Spain and Finland). They all taught French as a Foreign…

  7. Academic Knowledge Construction and Multimodal Curriculum Development

    ERIC Educational Resources Information Center

    Loveless, Douglas J., Ed.; Griffith, Bryant, Ed.; Bérci, Margaret E., Ed.; Ortlieb, Evan, Ed.; Sullivan, Pamela, Ed.

    2014-01-01

    While incorporating digital technologies into the classroom has offered new ways of teaching and learning into educational processes, it is essential to take a look at how the digital shift impacts teachers, school administration, and curriculum development. "Academic Knowledge Construction and Multimodal Curriculum Development" presents…

  8. Naming Block Structures: A Multimodal Approach

    ERIC Educational Resources Information Center

    Cohen, Lynn; Uhry, Joanna

    2011-01-01

    This study describes symbolic representation in block play in a culturally diverse suburban preschool classroom. Block play is "multimodal" and can allow children to experiment with materials to represent the world in many forms of literacy. Combined qualitative and quantitative data from seventy-seven block structures were collected and analyzed.…

  9. Multimodality, Translingualism, and Rhetorical Genre Studies

    ERIC Educational Resources Information Center

    Gonzales, Laura

    2015-01-01

    This article situates one possible future for rhetorical genre studies (RGS) in the translingual, multimodal composing practices of linguistically diverse composition students. Using focus group data collected with L1 (English as a first language) and L2 (English as a second language) students at two large public state universities, the researcher…

  10. Naming Block Structures: A Multimodal Approach

    ERIC Educational Resources Information Center

    Cohen, Lynn; Uhry, Joanna

    2011-01-01

    This study describes symbolic representation in block play in a culturally diverse suburban preschool classroom. Block play is "multimodal" and can allow children to experiment with materials to represent the world in many forms of literacy. Combined qualitative and quantitative data from seventy-seven block structures were collected and analyzed.…

  11. Controllable spatiotemporal nonlinear effects in multimode fibres

    NASA Astrophysics Data System (ADS)

    Wright, Logan G.; Christodoulides, Demetrios N.; Wise, Frank W.

    2015-05-01

    Multimode fibres are of interest for next-generation telecommunications systems and the construction of high-energy fibre lasers. However, relatively little work has explored nonlinear pulse propagation in multimode fibres. Here, we consider highly nonlinear ultrashort pulse propagation in the anomalous-dispersion regime of a graded-index multimode fibre. Low modal dispersion and strong nonlinear coupling between the fibre's many spatial modes result in interesting behaviour. We observe spatiotemporal effects reminiscent of nonlinear optics in bulk media—self-focusing and multiple filamentation—at a fraction of the usual power. By adjusting the spatial initial conditions, we generate on-demand, megawatt, ultrashort pulses tunable between 1,550 and 2,200 nm dispersive waves over one octave; intense combs of visible light; and a multi-octave-spanning supercontinuum. Our results indicate that multimode fibres present unique opportunities for observing new spatiotemporal dynamics and phenomena. They also enable the realization of a new type of tunable, broadband fibre source that could be useful for many applications.

  12. Multimodal Student Interaction Online: An Ecological Perspective

    ERIC Educational Resources Information Center

    Berglund, Therese Ornberg

    2009-01-01

    This article describes the influence of tool and task design on student interaction in language learning at a distance. Interaction in a multimodal desktop video conferencing environment, FlashMeeting, is analyzed from an ecological perspective with two main foci: participation rates and conversational feedback strategies. The quantitative…

  13. Multimodal Analgesia in the Hip Fracture Patient.

    PubMed

    Fabi, David W

    2016-05-01

    Hip fracture is one of the most common injuries among the elderly and, because the population is aging, it is expected to remain a major clinical challenge and public health problem for the foreseeable future. The clinical importance of early mobilization and prompt participation in physical therapy after hip fracture surgery is now widely recognized. Because postoperative pain can impair mobility and delay physical therapy, much attention is now being paid to finding more effective ways of controlling pain after hip fracture. Oversedation with opioid drugs inhibits communication between the patient and the health care team, can delay ambulation and rehabilitation therapy, and may increase the probability of the patient requiring a skilled nursing facility, which adds further cost to the overall health care system. Multiple pain pathways contribute to the perception of postoperative pain, and although opioids are highly effective in blocking nociceptive pain through inhibition of the mu receptors, they do not block other pain pathways. Multimodal analgesia involves the use of several anesthetic and analgesic modalities that are strategically combined to block pain perception at different sites in the peripheral and central nervous systems. This balanced, multifaceted approach provides more effective control of postoperative pain than opioid drugs alone, allows lower doses of opioids to be used as part of the multimodal regimen (thereby reducing the risk of opioid-related adverse events and complications), and may facilitate more rapid recovery and improve certain outcome measures related to recovery time. One prospective randomized study evaluating the clinical value of multimodal pain management in elderly patients undergoing bipolar hip hemiarthroplasty found that a multimodal regimen, including preemptive pain medication and intraoperative periarticular injections, reduced pain on postoperative days 1 and 4, and reduced overall opioid use. This article describes

  14. Hierarchical segmentation-assisted multimodal registration for MR brain images.

    PubMed

    Lu, Huanxiang; Beisteiner, Roland; Nolte, Lutz-Peter; Reyes, Mauricio

    2013-04-01

    Information theory-based metric such as mutual information (MI) is widely used as similarity measurement for multimodal registration. Nevertheless, this metric may lead to matching ambiguity for non-rigid registration. Moreover, maximization of MI alone does not necessarily produce an optimal solution. In this paper, we propose a segmentation-assisted similarity metric based on point-wise mutual information (PMI). This similarity metric, termed SPMI, enhances the registration accuracy by considering tissue classification probabilities as prior information, which is generated from an expectation maximization (EM) algorithm. Diffeomorphic demons is then adopted as the registration model and is optimized in a hierarchical framework (H-SPMI) based on different levels of anatomical structure as prior knowledge. The proposed method is evaluated using Brainweb synthetic data and clinical fMRI images. Both qualitative and quantitative assessment were performed as well as a sensitivity analysis to the segmentation error. Compared to the pure intensity-based approaches which only maximize mutual information, we show that the proposed algorithm provides significantly better accuracy on both synthetic and clinical data.

  15. Multimodal Neuroimaging Feature Learning with Multimodal Stacked Deep Polynomial Networks for Diagnosis of Alzheimer's Disease.

    PubMed

    Shi, Jun; Zheng, Xiao; Li, Yan; Zhang, Qi; Ying, Shihui

    2017-01-19

    The accurate diagnosis of Alzheimer's disease (AD) and its early stage, i.e. mild cognitive impairment (MCI), is essential for timely treatment and possible delay of AD. Fusion of multimodal neuroimaging data, such as magnetic resonance imaging (MRI) and positron emission tomography (PET), has shown its effectiveness for AD diagnosis. The deep polynomial networks (DPN) is a recently proposed deep learning algorithm, which performs well on both large-scale and small-size datasets. In this study, a multimodal stacked DPN (MM-SDPN) algorithm, which MM-SDPN consists of two-stage SDPNs, is proposed to fuse and learn feature representation from multimodal neuroimaging data for AD diagnosis. Specifically speaking, two SDPNs are first used to learn high-level features of MRI and PET, respectively, which are then fed to another SDPN to fuse multimodal neuroimaging information. The proposed MM-SDPN algorithm is applied to the ADNI dataset to conduct both binary classification and multiclass classification tasks. Experimental results indicate that MM-SDPN is superior over the state-of-the-art multimodal feature learning based algorithms for AD diagnosis.

  16. A Multimodal Nanocomposite for Biomedical Imaging

    PubMed Central

    Wu, Aiguo; Paunesku, Tatjana; Zhang, Zhuoli; Vogt, Stefan; Lai, Barry; Maser, Jörg; Yaghmai, Vahid; Li, Debiao; Omary, Reed A.; Woloschak, Gayle E.

    2013-01-01

    A multimodal nanocomposite was designed, synthesized with super-paramagnetic core (CoFe2O4), noble metal corona (Au), and semiconductor shell (TiO2). The sizes of core, core-corona, and core-corona-shell particles were determined by TEM. This multimodal nanocrystal showed promise as a contrast agent for two of the most widely used biomedical imaging techniques: magnetic resonance imaging (MRI) and X-ray computed tomography (CT). Finally, these nanocomposites were coated with a peptide SN-50. This led to their ready uptake by the cultured cells and targeted the nanocomposites to the pores of nuclear membrane. Inside cells, this nanocomposite retained its integrity as shown by X-ray fluorescence microscopy (XFM). Inside cells imaged by XFM we found the complex elemental signature of nanoconjugates (Ti-Co-Fe-Au) always co-registered in the 2D elemental map of the cell. PMID:24817775

  17. Multimode optomechanical system in the quantum regime.

    PubMed

    Nielsen, William Hvidtfelt Padkær; Tsaturyan, Yeghishe; Møller, Christoffer Bo; Polzik, Eugene S; Schliesser, Albert

    2017-01-03

    We realize a simple and robust optomechanical system with a multitude of long-lived (Q > 10(7)) mechanical modes in a phononic-bandgap shielded membrane resonator. An optical mode of a compact Fabry-Perot resonator detects these modes' motion with a measurement rate (96 kHz) that exceeds the mechanical decoherence rates already at moderate cryogenic temperatures (10 K). Reaching this quantum regime entails, inter alia, quantum measurement backaction exceeding thermal forces and thus strong optomechanical quantum correlations. In particular, we observe ponderomotive squeezing of the output light mediated by a multitude of mechanical resonator modes, with quantum noise suppression up to -2.4 dB (-3.6 dB if corrected for detection losses) and bandwidths ≲90 kHz. The multimode nature of the membrane and Fabry-Perot resonators will allow multimode entanglement involving electromagnetic, mechanical, and spin degrees of freedom.

  18. Fock expansion of multimode pure Gaussian states

    SciTech Connect

    Cariolaro, Gianfranco; Pierobon, Gianfranco

    2015-12-15

    The Fock expansion of multimode pure Gaussian states is derived starting from their representation as displaced and squeezed multimode vacuum states. The approach is new and appears to be simpler and more general than previous ones starting from the phase-space representation given by the characteristic or Wigner function. Fock expansion is performed in terms of easily evaluable two-variable Hermite–Kampé de Fériet polynomials. A relatively simple and compact expression for the joint statistical distribution of the photon numbers in the different modes is obtained. In particular, this result enables one to give a simple characterization of separable and entangled states, as shown for two-mode and three-mode Gaussian states.

  19. Comparing Paper and Tangible, Multimodal Tools

    SciTech Connect

    McGee, David R. ); Cohen, Philip R.; Wesson, R M.; Horman, Sheilah

    2002-01-01

    Officers in command posts maintain situational awareness using paper maps, Post-it notes, and hand-written annotations. They do so because paper is robust to failure, it is portable and malleable, it offers ultra-high resolution and supports face-to-face collaboration. We report herein on an evaluation comparing maps and Post-its with a tangible multimodal system called Rasa that augments the paper tools with sensors, enabling it to recognize the multimodal language (both written and spoken) that naturally occurs there. In this study, we found that not only do users prefer Rasa to paper alone, they find it as easy or easier to use than paper tools. Moreover, Rasa introduces no discernible overhead in its operation other than error repair, yet grants the benefits inherent in digital systems. Finally, subjects confirmed that by combining physical and computational tools, Rasa is resistant to computational failure.

  20. Multimodal mechanisms of food creaminess sensation.

    PubMed

    Chen, Jianshe; Eaton, Louise

    2012-12-01

    In this work, the sensory creaminess of a set of four viscosity-matched fluid foods (single cream, evaporated milk, corn starch solution, and corn starch solution containing long chain free fatty acids) was tested by a panel of 16 assessors via controlled sensation mechanisms of smell only, taste only, taste and tactile, and integrated multimodal. It was found that all sensation channels were able to discriminate between creamy and non-creamy foods, but only the multimodal method gave creaminess ratings in agreement with the samples' fat content. Results from this study show that the presence of long chain free fatty acids has no influence on creaminess perception. It is certain that food creaminess is not a primary sensory property but an integrated sensory perception (or sensory experience) derived from combined sensations of visual, olfactory, gustatory, and tactile cues. Creamy colour, milky flavour, and smooth texture are probably the most important sensory features of food creaminess.

  1. Multimode optomechanical system in the quantum regime

    NASA Astrophysics Data System (ADS)

    Hvidtfelt Padkær Nielsen, William; Tsaturyan, Yeghishe; Møller, Christoffer Bo; Polzik, Eugene S.; Schliesser, Albert

    2017-01-01

    We realize a simple and robust optomechanical system with a multitude of long-lived (Q > 107) mechanical modes in a phononic-bandgap shielded membrane resonator. An optical mode of a compact Fabry–Perot resonator detects these modes’ motion with a measurement rate (96 kHz) that exceeds the mechanical decoherence rates already at moderate cryogenic temperatures (10 K). Reaching this quantum regime entails, inter alia, quantum measurement backaction exceeding thermal forces and thus strong optomechanical quantum correlations. In particular, we observe ponderomotive squeezing of the output light mediated by a multitude of mechanical resonator modes, with quantum noise suppression up to ‑2.4 dB (‑3.6 dB if corrected for detection losses) and bandwidths ≲90 kHz. The multimode nature of the membrane and Fabry–Perot resonators will allow multimode entanglement involving electromagnetic, mechanical, and spin degrees of freedom.

  2. Multimode fibres for micro-endoscopy

    NASA Astrophysics Data System (ADS)

    Turtaev, Sergey; Leite, Ivo T.; Čižmár, Tomáš

    2015-12-01

    There has been a tremendous effort in modern microscopy towards miniaturisation and fibre-based technology, driven by the need to access hostile or difficult environments in situ and in vivo. Most of these rely on reducing the size of endoscopes based on fibre-optic bundles, and systems incorporating microfabricated lenses. Recently, the use of standard multimode optical fibres for lensless microscopy has become possible mainly due to advances in holographic beam shaping. This article reviews the methods and techniques behind this progress paving theway towards minimally invasive in vivo imaging as well as other applications of multimode waveguides including on-chip integration of optical micro-manipulation and numerous other biophotonics techniques.

  3. Towards multimodal nonlinear optical tomography - experimental methodology

    NASA Astrophysics Data System (ADS)

    Vogler, N.; Medyukhina, A.; Latka, I.; Kemper, S.; Böhm, M.; Dietzek, B.; Popp, J.

    2011-08-01

    All-optical microspectroscopic and tomographic tools reveal great potential for clinical dermatologic diagnostics, i.e., investigation of human skin and skin diseases. While optical-coherence tomography has been complemented by two-photon fluorescence tomography and second-harmonic generation tomography, a joint study of various nonlinear optical microspectroscopies, i.e., application of the recently developed multimodal imaging approach, to sizable human-tissue samples has not been evaluated up to now. Here, we present such multimodal approach combining different nonlinear optical contrast mechanisms for imaging, namely two-photon excited fluorescence (TPF), second-harmonic generation (SHG), and coherent anti-Stokes Raman scattering (CARS) into a joint microscopic experiment. We show the potential of imaging large skin areas and discuss the information obtained in a case study comparing normal skin and keloid tissue.

  4. Multimode directionality in all-dielectric metasurfaces

    NASA Astrophysics Data System (ADS)

    Yang, Yuanqing; Miroshnichenko, Andrey E.; Kostinski, Sarah V.; Odit, Mikhail; Kapitanova, Polina; Qiu, Min; Kivshar, Yuri S.

    2017-04-01

    We demonstrate that spectrally diverse multiple magnetic dipole resonances can be excited in all-dielectric structures lacking rotational symmetry, in contrast to conventionally used spheres, disks, or spheroids. Such multiple magnetic resonances arise from hybrid Mie-Fabry-Perot modes, and can constructively interfere with induced electric dipole moments, thereby leading to novel multifrequency unidirectional scattering. Here we focus on elongated dielectric nanobars, whose magnetic resonances can be spectrally tuned by their aspect ratios. Based on our theoretical results, we suggest all-dielectric multimode metasurfaces and verify them in proof-of-principle microwave experiments. We also believe that the demonstrated property of multimode directionality is largely responsible for the best efficiency of all-dielectric metasurfaces that were recently shown to operate across multiple telecom bands.

  5. A Multimodal Nanocomposite for Biomedical Imaging

    NASA Astrophysics Data System (ADS)

    Wu, A.; Paunesku, T.; Zhang, Z.; Vogt, S.; Lai, B.; Maser, J.; Yaghmai, V.; Li, D.; Omary, R. A.; Woloschak, G. E.

    2011-09-01

    A multimodal nanocomposite was designed, synthesized with super-paramagnetic core (CoFe2O4), noble metal corona (Au), and semiconductor shell (TiO2). The sizes of core, core-corona, and core-corona-shell particles were determined by TEM. This multimodal nanocrystal showed promise as a contrast agent for two of the most widely used biomedical imaging techniques: magnetic resonance imaging (MRI) and x-ray computed tomography (CT). Finally, these nanocomposites were coated with a peptide SN-50. This led to their ready uptake by the cultured cells and targeted the nanocomposites to the pores of nuclear membrane. Inside cells, this nanocomposite retained its integrity as shown by x-ray fluorescence microscopy (XFM). Inside cells imaged by XFM we found the complex elemental signature of nanoconjugates (Ti-Co-Fe-Au) always co-registered in the 2D elemental map of the cell.

  6. Fabrication and modeling of multimode fiber lenses.

    PubMed

    Bescherer, Klaus; Munzke, Dorit; Reich, Oliver; Loock, Hans-Peter

    2013-02-01

    We report on the fabrication, modeling, and experimental verification of the emission of fiber lenses fabricated on multimode fibers in different media. Concave fiber lenses with a radius of 150 μm were fabricated onto a multimode silica fiber (100 μm core) by grinding and polishing against a ruby sphere template. In our theoretical model we assume that the fiber guides light from a Lambertian light source and that the emission cone is governed solely by the range of permitted emission angles. We investigate concave and convex lenses at 532 nm with different radii and in a variety of surrounding media from air (n(0)=1.00) to sapphire (n(0)=1.77). It was found that noticeable focusing or defocusing effects of a silica fiber lens in ethanol (n(0)=1.36) and dimethyl sulfoxide (DMSO) (n(0)=1.48) are only observed when the fiber lens radius was less than the fiber diameter.

  7. Multimodality imaging in nanomedicine and nanotheranostics

    PubMed Central

    Li, Xue; Zhang, Xue-Ning; Li, Xiao-Dong; Chang, Jin

    2016-01-01

    Accurate diagnosis of tumors needs much detailed information. However, available single imaging modality cannot provide complete or comprehensive data. Nanomedicine is the application of nanotechnology to medicine, and multimodality imaging based on nanoparticles has been receiving extensive attention. This new hybrid imaging technology could provide complementary information from different imaging modalities using only a single injection of contrast agent. In this review, we introduce recent developments in multifunctional nanoparticles and their biomedical applications to multimodal imaging and theragnosis as nanomedicine. Most of the reviewed studies are based on the intrinsic properties of nanoparticles and their application in clinical imaging technology. The imaging techniques include positron emission tomography, single-photon emission computed tomography, computerized tomography, magnetic resonance imaging, optical imaging, and ultrasound imaging. PMID:27807501

  8. Robust Multimodal Cognitive Load Measurement (RMCLM)

    DTIC Science & Technology

    2013-03-26

    Eye Activity for Cognitive Load Measurement with Emotion Interference,” Computer Methods and Programs in Biomedicine, 2012. b) Papers published in...Signals for CLM 4. Eye Activity for CLM with Emotion Interference 5. Linguistic and Grammatical Features for CLM 6. Conclusions and Future Work...Cognitive Load Measurement with Emotion Interference Attachment F Multimodal Behaviour and Interaction as Indicators of Cognitive Load Attachment G

  9. Baseline and Multimodal UAV GCS Interface Design

    DTIC Science & Technology

    2011-12-01

    duty cycles. 3.2.2 Drawing Line of Tactors Spatial - temporal patterns and perceptions of apparent movement can be generated by sequentially activating...efficacy of a multimodal GCS display for enhancing supervisory control for automated landing. It is expected that the findings from this study will have...7 2 Auditory and Tactile Displays for Enhancing Monitoring Automated UAVs ......................... 8 2.1 Literature on Auditory and Tactile

  10. Multimodal Sensor Fusion for Personnel Detection

    DTIC Science & Technology

    2011-07-01

    Multimodal Sensor Fusion for Personnel Detection Xin Jin Shalabh Gupta Asok Ray Department of Mechanical Engineering The Pennsylvania State...have con- sidered relations taken only two at a time, but we propose to explore relations between higher order cliques as future work. D. Feature...detection,” IEEE Transactions on Pattern Analysis and Machine Intelligence, vol. 23, no. 6, pp. 577–589, 2001. [11] A. Ray , “Symbolic dynamic analysis

  11. Multimodal Semantic Analysis of Public Transport Movements

    NASA Astrophysics Data System (ADS)

    Halb, Wolfgang; Neuschmied, Helmut

    We present a system for multimodal, semantic analysis of person movements that incorporates data from surveillance cameras, weather sensors, and third-party information providers. The interactive demonstration will show the automated creation of a survey of passenger transfer behavior at a public transport hub. Such information is vital for public transportation planning and the presented approach increases the cost-effectiveness and data accuracy as compared to traditional methods.

  12. Ultrabroadband Dispersive Radiation by Spatiotemporal Oscillation of Multimode Waves.

    PubMed

    Wright, Logan G; Wabnitz, Stefan; Christodoulides, Demetrios N; Wise, Frank W

    2015-11-27

    In nonlinear dynamical systems, qualitatively distinct phenomena occur depending continuously on the size of the bounded domain containing the system. For nonlinear waves, a multimode waveguide is a bounded three-dimensional domain, allowing observation of dynamics impossible in open settings. Here we study radiation emitted by bounded nonlinear waves: the spatiotemporal oscillations of solitons in multimode fiber generate multimode dispersive waves over an ultrabroadband spectral range. This work suggests routes to sources of coherent electromagnetic waves with unprecedented spectral range.

  13. Medical Image Retrieval: A Multimodal Approach

    PubMed Central

    Cao, Yu; Steffey, Shawn; He, Jianbiao; Xiao, Degui; Tao, Cui; Chen, Ping; Müller, Henning

    2014-01-01

    Medical imaging is becoming a vital component of war on cancer. Tremendous amounts of medical image data are captured and recorded in a digital format during cancer care and cancer research. Facing such an unprecedented volume of image data with heterogeneous image modalities, it is necessary to develop effective and efficient content-based medical image retrieval systems for cancer clinical practice and research. While substantial progress has been made in different areas of content-based image retrieval (CBIR) research, direct applications of existing CBIR techniques to the medical images produced unsatisfactory results, because of the unique characteristics of medical images. In this paper, we develop a new multimodal medical image retrieval approach based on the recent advances in the statistical graphic model and deep learning. Specifically, we first investigate a new extended probabilistic Latent Semantic Analysis model to integrate the visual and textual information from medical images to bridge the semantic gap. We then develop a new deep Boltzmann machine-based multimodal learning model to learn the joint density model from multimodal information in order to derive the missing modality. Experimental results with large volume of real-world medical images have shown that our new approach is a promising solution for the next-generation medical imaging indexing and retrieval system. PMID:26309389

  14. [Multimodal therapy programs for chronic pain].

    PubMed

    Kopf, A; Gjoni, E

    2015-02-01

    Chronic pain is a common and disabling disorder with major consequences for patient quality of life and it is also a major economic burden to society. The management of chronic pain comprises a large range of different intervention strategies including pharmacological therapy, non-medicinal and invasive therapeutic options. While non-pharmacological and multimodal options are underused, monomodal options, especially pharmacotherapy and invasive therapies are overused. The effectiveness of multidisciplinary and multimodal treatment programs including physical and rehabilitation interventions and psychological treatment has been extensively studied in the last two decades. Evidence from randomized controlled trials demonstrates that there is low quality evidence for the effectiveness of exercise therapy alone, there is some evidence for the effectiveness of behavioral therapy and there is at least moderate evidence for the effectiveness of multidisciplinary and multimodal treatment and other active treatment reducing pain and increasing functional capacity at short and intermediate term. Therefore, blanket coverage with provision of adequate treatment programs for chronic pain as well as studies evaluating the best composition of treatment elements are needed. The characteristics of chronic pain, the necessary assessment procedures and treatment types are described.

  15. Multimode-Optical-Fiber Imaging Probe

    NASA Technical Reports Server (NTRS)

    Jackson, Deborah

    1999-01-01

    Currently, endoscopic surgery uses single-mode fiber-bundles to obtain in vivo image information inside the orifices of the body. This limits their use to the larger natural orifices and to surgical procedures where there is plenty of room for manipulation. The knee joint, for example, can be easily viewed with a fiber optic viewer, but joints in the finger cannot. However, there are a host of smaller orifices where fiber endoscopy would play an important role if a cost effective fiber probe were developed with small enough dimensions (less than or equal to 250 microns). Examples of beneficiaries of micro-endoscopes are the treatment of the Eustatian tube of the middle ear, the breast ducts, tear ducts, coronary arteries, fallopian tubes, as well as the treatment of salivary duct parotid disease, and the neuro endoscopy of the ventricles and spinal canal. This work describes an approach for recovering images from tightly confined spaces using multimode. The concept draws upon earlier works that concentrated on image recovery after two-way transmission through a multimode fiber as well as work that demonstrated the recovery of images after one-way transmission through a multimode fiber. Both relied on generating a phase conjugated wavefront, which was predistorted with the characteristics of the fiber. The approach described here also relies on generating a phase conjugated wavefront, but utilizes two fibers to capture the image at some intermediate point (accessible by the fibers, but which is otherwise visually inaccessible).

  16. Nonclassical distance in multimode bosonic systems

    NASA Astrophysics Data System (ADS)

    Nair, Ranjith

    2017-06-01

    We revisit the notion of nonclassical distance of states of bosonic quantum systems introduced in Phys. Rev. A 35, 725 (1987), 10.1103/PhysRevA.35.725 in a general multimode setting. After reviewing its definition, we establish some of its general properties. We obtain new upper and lower bounds on the nonclassical distance in terms of the supremum of the Husimi function of the state. Considering several examples, we elucidate the cases for which our lower bound is tight, which include the multimode number states and a class of multimode NOON states. The latter provide examples of states of definite photon number n ≥2 whose nonclassical distance can be made arbitrarily close to the upper limit of 1 by increasing the number of modes. We show that the nonclassical distance of the even and odd Schrödinger cat states is bounded away from unity regardless of how macroscopic the superpositions are, and that the nonclassical distance is not necessarily monotonically increasing with respect to macroscopicity.

  17. Laplacian eigenmaps for multimodal groupwise image registration

    NASA Astrophysics Data System (ADS)

    Polfliet, Mathias; Klein, Stefan; Niessen, Wiro J.; Vandemeulebroucke, Jef

    2017-02-01

    Multimodal groupwise registration has been of growing interest to the image processing community due to developments in scanner technologies (e.g. multiparametric MRI, DCE-CT or PET-MR) that increased both the number of modalities and number of images under consideration. In this work a novel methodology is presented for multimodal groupwise registration that is based on Laplacian eigenmaps, a nonlinear dimensionality reduction technique. Compared to recently proposed dissimilarity metrics based on principal component analysis, the proposed metric should enable a better capture of the intensity relationships between different images in the group. The metric is constructed to be the second smallest eigenvalue from the eigenvector problem defined in Laplacian eigenmaps. The method was validated in three distinct experiments: a non-linear synthetic registration experiment, the registration of quantitative MRI data of the carotid artery, and the registration of multimodal data of the brain (RIRE). The results show increased accuracy and robustness compared to other state-of-the-art groupwise registration methodologies.

  18. Multimodal Neuroimaging in Schizophrenia: Description and Dissemination.

    PubMed

    Aine, C J; Bockholt, H J; Bustillo, J R; Cañive, J M; Caprihan, A; Gasparovic, C; Hanlon, F M; Houck, J M; Jung, R E; Lauriello, J; Liu, J; Mayer, A R; Perrone-Bizzozero, N I; Posse, S; Stephen, J M; Turner, J A; Clark, V P; Calhoun, Vince D

    2017-08-15

    In this paper we describe an open-access collection of multimodal neuroimaging data in schizophrenia for release to the community. Data were acquired from approximately 100 patients with schizophrenia and 100 age-matched controls during rest as well as several task activation paradigms targeting a hierarchy of cognitive constructs. Neuroimaging data include structural MRI, functional MRI, diffusion MRI, MR spectroscopic imaging, and magnetoencephalography. For three of the hypothesis-driven projects, task activation paradigms were acquired on subsets of ~200 volunteers which examined a range of sensory and cognitive processes (e.g., auditory sensory gating, auditory/visual multisensory integration, visual transverse patterning). Neuropsychological data were also acquired and genetic material via saliva samples were collected from most of the participants and have been typed for both genome-wide polymorphism data as well as genome-wide methylation data. Some results are also presented from the individual studies as well as from our data-driven multimodal analyses (e.g., multimodal examinations of network structure and network dynamics and multitask fMRI data analysis across projects). All data will be released through the Mind Research Network's collaborative informatics and neuroimaging suite (COINS).

  19. Enhancing impedance imaging through multimodal tomography.

    PubMed

    Gürsoy, Doğa; Mamatjan, Yasin; Adler, Andy; Scharfetter, Hermann

    2011-11-01

    Several noninvasive modalities including electrical impedance tomography (EIT), magnetic induction tomography (MIT), and induced-current EIT (ICEIT) have been developed for imaging the electrical conductivity distribution within a human body. Although these modalities differ in how the excitation and detection circuitry (electrodes or coils) are implemented, they share a number of common principles not only within the image reconstruction approaches but also with respect to the basic principle of generating a current density distribution inside a body and recording the resultant electric fields. In this paper, we are interested in comparing differences between these modalities and in theoretically understanding the compromises involved, despite the increased hardware cost and complexity that such a multimodal system brings along. To systematically assess the merits of combining data, we performed 3-D simulations for each modality and for the multimodal system by combining all available data. The normalized sensitivity matrices were computed for each modality based on the finite element method, and singular value decomposition was performed on the resultant matrices. We used both global and regional quality measures to evaluate and compare different modalities. This study has shown that the condition number of the sensitivity matrix obtained from the multimodal tomography with 16-electrode and 16-coil is much lower than the condition number produced in the conventional 16-channel EIT and MIT systems, and thus, produced promising results in terms of image stability. An improvement of about 20% in image resolution can be achieved considering feasible signal-to-noise ratio levels.

  20. Multimode Strong Coupling in Circuit QED

    NASA Astrophysics Data System (ADS)

    Sundaresan, Neereja; Liu, Yanbing; Sadri, Darius; Szocs, Laszlo; Underwood, Devin; Malekakhlagh, Moein; Tureci, Hakan; Houck, Andrew

    We present experimental and theoretical studies in the multimode strong coupling (MMSC) regime of cavity quantum electrodynamics (QED). In MMSC, a single atom is simultaneously coupled to a large, but discrete, number of cavity harmonics, with atom-mode coupling strengths comparable to the free spectral range (FSR). This regime is readily accessible in circuit QED, by strongly coupling a transmon qubit to a low fundamental frequency microwave cavity. We present some key results from our original experiment (PRX 5, 021035, 2015), in which a transmon qubit, resonant with the 75th harmonic of a 90 MHz cavity, reached qubit-mode coupling strengths exceeding 30MHz. When this system is coherently driven, we observed complex multimode fluorescence, with the notable formation of ultra-narrow linewidths. To better understand these unique features of multimode resonance fluorescence we developed a quantum formalism, which attributes the spectral linewidth narrowing to the correlated spontaneous emission of doubly dressed states. Finally we will share preliminary experimental results from our continuing study of MMSC, this time from a system where qubit-mode coupling strengths approach and even exceed the FSR.

  1. Multimodality bonchoscopic imaging of tracheopathica osteochondroplastica

    NASA Astrophysics Data System (ADS)

    Colt, Henri; Murgu, Septimiu D.; Ahn, Yeh-Chan; Brenner, Matt

    2009-05-01

    Results of a commercial optical coherence tomography system used as part of a multimodality diagnostic bronchoscopy platform are presented for a 61-year-old patient with central airway obstruction from tracheopathica osteochondroplastica. Comparison to results of white-light bronchoscopy, histology, and endobronchial ultrasound examination are accompanied by a discussion of resolution, penetration depth, contrast, and field of view of these imaging modalities. White-light bronchoscopy revealed irregularly shaped, firm submucosal nodules along cartilaginous structures of the anterior and lateral walls of the trachea, sparing the muscular posterior membrane. Endobronchial ultrasound showed a hyperechoic density of 0.4 cm thickness. optical coherence tomography (OCT) was performed using a commercially available, compact time-domain OCT system (Niris System, Imalux Corp., Cleveland, Ohio) with a magnetically actuating probe (two-dimensional, front imaging, and inside actuation). Images showed epithelium, upper submucosa, and osseous submucosal nodule layers corresponding with histopathology. To our knowledge, this is the first time these commercially available systems are used as part of a multimodality bronchoscopy platform to study diagnostic imaging of a benign disease causing central airway obstruction. Further studies are needed to optimize these systems for pulmonary applications and to determine how new-generation imaging modalities will be integrated into a multimodality bronchoscopy platform.

  2. Multimodal imaging of cutaneous wound tissue

    PubMed Central

    Zhang, Shiwu; Gnyawali, Surya; Huang, Jiwei; Ren, Wenqi; Gordillo, Gayle; Sen, Chandan K.; Xu, Ronald

    2015-01-01

    Abstract. Quantitative assessment of wound tissue ischemia, perfusion, and inflammation provides critical information for appropriate detection, staging, and treatment of chronic wounds. However, few methods are available for simultaneous assessment of these tissue parameters in a noninvasive and quantitative fashion. We integrated hyperspectral, laser speckle, and thermographic imaging modalities in a single-experimental setup for multimodal assessment of tissue oxygenation, perfusion, and inflammation characteristics. Algorithms were developed for appropriate coregistration between wound images acquired by different imaging modalities at different times. The multimodal wound imaging system was validated in an occlusion experiment, where oxygenation and perfusion maps of a healthy subject’s upper extremity were continuously monitored during a postocclusive reactive hyperemia procedure and compared with standard measurements. The system was also tested in a clinical trial where a wound of three millimeters in diameter was introduced on a healthy subject’s lower extremity and the healing process was continuously monitored. Our in vivo experiments demonstrated the clinical feasibility of multimodal cutaneous wound imaging. PMID:25604545

  3. Multimodal neuroimaging computing: the workflows, methods, and platforms.

    PubMed

    Liu, Sidong; Cai, Weidong; Liu, Siqi; Zhang, Fan; Fulham, Michael; Feng, Dagan; Pujol, Sonia; Kikinis, Ron

    The last two decades have witnessed the explosive growth in the development and use of noninvasive neuroimaging technologies that advance the research on human brain under normal and pathological conditions. Multimodal neuroimaging has become a major driver of current neuroimaging research due to the recognition of the clinical benefits of multimodal data, and the better access to hybrid devices. Multimodal neuroimaging computing is very challenging, and requires sophisticated computing to address the variations in spatiotemporal resolution and merge the biophysical/biochemical information. We review the current workflows and methods for multimodal neuroimaging computing, and also demonstrate how to conduct research using the established neuroimaging computing packages and platforms.

  4. Multimodal neuroimaging computing: the workflows, methods, and platforms.

    PubMed

    Liu, Sidong; Cai, Weidong; Liu, Siqi; Zhang, Fan; Fulham, Michael; Feng, Dagan; Pujol, Sonia; Kikinis, Ron

    2015-09-01

    The last two decades have witnessed the explosive growth in the development and use of noninvasive neuroimaging technologies that advance the research on human brain under normal and pathological conditions. Multimodal neuroimaging has become a major driver of current neuroimaging research due to the recognition of the clinical benefits of multimodal data, and the better access to hybrid devices. Multimodal neuroimaging computing is very challenging, and requires sophisticated computing to address the variations in spatiotemporal resolution and merge the biophysical/biochemical information. We review the current workflows and methods for multimodal neuroimaging computing, and also demonstrate how to conduct research using the established neuroimaging computing packages and platforms.

  5. Multimodal integration of anatomy and physiology classes: How instructors utilize multimodal teaching in their classrooms

    NASA Astrophysics Data System (ADS)

    McGraw, Gerald M., Jr.

    Multimodality is the theory of communication as it applies to social and educational semiotics (making meaning through the use of multiple signs and symbols). The term multimodality describes a communication methodology that includes multiple textual, aural, and visual applications (modes) that are woven together to create what is referred to as an artifact. Multimodal teaching methodology attempts to create a deeper meaning to course content by activating the higher cognitive areas of the student's brain, creating a more sustained retention of the information (Murray, 2009). The introduction of multimodality educational methodologies as a means to more optimally engage students has been documented within educational literature. However, studies analyzing the distribution and penetration into basic sciences, more specifically anatomy and physiology, have not been forthcoming. This study used a quantitative survey design to determine the degree to which instructors integrated multimodality teaching practices into their course curricula. The instrument used for the study was designed by the researcher based on evidence found in the literature and sent to members of three associations/societies for anatomy and physiology instructors: the Human Anatomy and Physiology Society; the iTeach Anatomy & Physiology Collaborate; and the American Physiology Society. Respondents totaled 182 instructor members of two- and four-year, private and public higher learning colleges collected from the three organizations collectively with over 13,500 members in over 925 higher learning institutions nationwide. The study concluded that the expansion of multimodal methodologies into anatomy and physiology classrooms is at the beginning of the process and that there is ample opportunity for expansion. Instructors continue to use lecture as their primary means of interaction with students. Email is still the major form of out-of-class communication for full-time instructors. Instructors with

  6. Multimodal Research: Addressing the Complexity of Multimodal Environments and the Challenges for CALL

    ERIC Educational Resources Information Center

    Tan, Sabine; O'Halloran, Kay L.; Wignell, Peter

    2016-01-01

    Multimodality, the study of the interaction of language with other semiotic resources such as images and sound resources, has significant implications for computer assisted language learning (CALL) with regards to understanding the impact of digital environments on language teaching and learning. In this paper, we explore recent manifestations of…

  7. Multimodal Research: Addressing the Complexity of Multimodal Environments and the Challenges for CALL

    ERIC Educational Resources Information Center

    Tan, Sabine; O'Halloran, Kay L.; Wignell, Peter

    2016-01-01

    Multimodality, the study of the interaction of language with other semiotic resources such as images and sound resources, has significant implications for computer assisted language learning (CALL) with regards to understanding the impact of digital environments on language teaching and learning. In this paper, we explore recent manifestations of…

  8. Instantiation of Multimodal Semiotic Systems in Science Classroom Discourse

    ERIC Educational Resources Information Center

    Tang, Kok-Sing

    2013-01-01

    Science classroom discourse is inherently multimodal in that scientific meanings are made through an integration of multiple semiotic systems (e.g., language, diagrams, equations). Although some studies have described this multimodal nature, few have examined and explained the relationship between the integration of multiple semiotic systems and…

  9. Teaching Visual Texts with the Multimodal Analysis Software

    ERIC Educational Resources Information Center

    Lim Fei, Victor; O'Halloran, Kay L.; Tan, Sabine; E., Marissa K. L.

    2015-01-01

    This exploratory study introduces the systemic approach and the explicit teaching of a meta-language to provide conceptual tools for students for the analysis and interpretation of multimodal texts. Equipping students with a set of specialised vocabulary with conventionalised meanings associated with specific choices in multimodal texts empowers…

  10. Indigenous Ways with Literacies: Transgenerational, Multimodal, Placed, and Collective

    ERIC Educational Resources Information Center

    Mills, Kathy A.; Davis-Warra, John; Sewell, Marlene; Anderson, Mikayla

    2016-01-01

    This research describes some of the salient features of Indigenous ways of working with multimodal literacies in digital contexts of use that emerged within an Indigenous school community with the oversight of Aboriginal Elders. This is significant because the use of multimodal literacy practices among a growing number of Indigenous school…

  11. Level up with Multimodal Composition in Social Studies

    ERIC Educational Resources Information Center

    Dalton, Bridget

    2015-01-01

    Students find multimodal composing highly engaging. Even with students' investment in designing multimodal texts, the teaching process is complex. The purpose for writing, audience, and genre must be considered in relation to the modes, digital authoring and presentation tools, and technology devices that are available to the composer. This…

  12. Teaching Visual Texts with the Multimodal Analysis Software

    ERIC Educational Resources Information Center

    Lim Fei, Victor; O'Halloran, Kay L.; Tan, Sabine; E., Marissa K. L.

    2015-01-01

    This exploratory study introduces the systemic approach and the explicit teaching of a meta-language to provide conceptual tools for students for the analysis and interpretation of multimodal texts. Equipping students with a set of specialised vocabulary with conventionalised meanings associated with specific choices in multimodal texts empowers…

  13. The Effects of Multimodality through Storytelling Using Various Movie Clips

    ERIC Educational Resources Information Center

    Kim, SoHee

    2016-01-01

    This study examines the salient multimodal approaches for communicative competence and learners' reactions through storytelling tasks with three different modes: a silent movie clip, a movie clip with only sound effects, and a movie clip with sound effects and dialogue. In order to measure different multimodal effects and to define better delivery…

  14. Indigenous Ways with Literacies: Transgenerational, Multimodal, Placed, and Collective

    ERIC Educational Resources Information Center

    Mills, Kathy A.; Davis-Warra, John; Sewell, Marlene; Anderson, Mikayla

    2016-01-01

    This research describes some of the salient features of Indigenous ways of working with multimodal literacies in digital contexts of use that emerged within an Indigenous school community with the oversight of Aboriginal Elders. This is significant because the use of multimodal literacy practices among a growing number of Indigenous school…

  15. Using a Multimodal Learning System to Support Music Instruction

    ERIC Educational Resources Information Center

    Yu, Pao-Ta; Lai, Yen-Shou; Tsai, Hung-Hsu; Chang, Yuan-Hou

    2010-01-01

    This paper describes a multimodality approach that helps primary-school students improve their learning performance during music instruction. Multimedia instruction is an effective way to help learners create meaningful knowledge and to make referential connections between mental representations. This paper proposes a multimodal, dual-channel,…

  16. Remixing My Life: The Multimodal Literacy Memoir Assignment and STEM

    ERIC Educational Resources Information Center

    Pytash, Kristine E.; Kist, William; Testa, Elizabeth

    2017-01-01

    The authors explore the experiences and multimodal compositions of a student at a STEM (science, technology, engineering, and mathematics) high school who opted to take an elective course on multimodal autobiography. They document how her meaning making included her beliefs and perspectives about the world, as well as a finely developed aesthetic…

  17. Multimodal Pedagogies in Diverse Classrooms: Representation, Rights and Resources

    ERIC Educational Resources Information Center

    Stein, Pippa

    2012-01-01

    Multimodal Pedagogies in Diverse Classrooms examines how the classroom can become a democratic space founded on the integration of different histories, modes of representation, feelings, languages and discourses, and is essential reading for anyone interested in the connection between multimodality, pedagogy, democracy and social justice in…

  18. Composition 2.0: Toward a Multilingual and Multimodal Framework

    ERIC Educational Resources Information Center

    Fraiberg, Steven

    2010-01-01

    This article argues that tracing multimodal-multilingual literacy practices across official and unofficial spaces is key to moving composition into the twenty-first century. Key to this remixing of the field is a situated framework that locates multimodal-multilingual activities in wider genre, cultural, national, and global ecologies. (Contains 3…

  19. Cultural Shifts, Multimodal Representations, and Assessment Practices: A Case Study

    ERIC Educational Resources Information Center

    Curwood, Jen Scott

    2012-01-01

    Multimodal texts involve the presence, absence, and co-occurrence of alphabetic text with visual, audio, tactile, gestural, and spatial representations. This article explores how teachers' evaluation of students' multimodal work can be understood in terms of cognition and culture. When teachers apply a paradigm of assessment rooted in print-based…

  20. Expanding Perspectives for Comprehending Visual Images in Multimodal Texts

    ERIC Educational Resources Information Center

    Serafini, Frank

    2011-01-01

    The texts that adolescents encounter today are often multimodal, meaning they incorporate a variety of modes, including visual images, hypertext, and graphic design elements along with written text. Expanding the perspectives readers use to make sense of the multimodal texts is an important aspect of comprehension instruction. Moving beyond the…

  1. Composition at Washington State University: Building a Multimodal Bricolage

    ERIC Educational Resources Information Center

    Ericsson, Patricia; Hunter, Leeann Downing; Macklin, Tialitha Michelle; Edwards, Elizabeth Sue

    2016-01-01

    Multimodal pedagogy is increasingly accepted among composition scholars. However, putting such pedagogy into practice presents significant challenges. In this profile of Washington State University's first-year composition program, we suggest a multi-vocal and multi-theoretical approach to addressing the challenges of multimodal pedagogy. Patricia…

  2. Expanding Perspectives for Comprehending Visual Images in Multimodal Texts

    ERIC Educational Resources Information Center

    Serafini, Frank

    2011-01-01

    The texts that adolescents encounter today are often multimodal, meaning they incorporate a variety of modes, including visual images, hypertext, and graphic design elements along with written text. Expanding the perspectives readers use to make sense of the multimodal texts is an important aspect of comprehension instruction. Moving beyond the…

  3. Multimodal Teaching and Learning: Creating Spaces for Content Teachers

    ERIC Educational Resources Information Center

    Thompson, Mary

    2008-01-01

    In this article, the author describes her multimodal teaching practices in her "Adolescent Literacy Methods" course at a graduate university in the United States. By doing so, she highlights content teacher's understanding and use of various multimodal texts to effectively teach adolescents inside the classroom. In lieu of this, she raises…

  4. Using Multimodal Writing to Motivate Struggling Students to Write

    ERIC Educational Resources Information Center

    Darrington, Brett; Dousay, Tonia

    2014-01-01

    One of the reasons that many secondary students fail English classes is because they are not motivated to write. This literature review was conducted to look into the use of multimodal works to increase the motivation for struggling students to write. Change theory was used to evaluate the benefits of multimodal works compared to more traditional…

  5. Critical Visual Literacy: Multimodal Communication across the Curriculum

    ERIC Educational Resources Information Center

    Duffelmeyer, Barb Blakely; Ellertson, Anthony

    2005-01-01

    "Critical Visual Literacy: Multimodal Communication Across the Curriculum" makes the case for expanding the pedagogical space and communication possibilities in undergraduate communication-intensive and linked (learning community) courses by allowing students to create multimodal texts that deal with civic and cultural and/or discipline…

  6. Using a Multimodal Learning System to Support Music Instruction

    ERIC Educational Resources Information Center

    Yu, Pao-Ta; Lai, Yen-Shou; Tsai, Hung-Hsu; Chang, Yuan-Hou

    2010-01-01

    This paper describes a multimodality approach that helps primary-school students improve their learning performance during music instruction. Multimedia instruction is an effective way to help learners create meaningful knowledge and to make referential connections between mental representations. This paper proposes a multimodal, dual-channel,…

  7. Multimodal Pedagogies in Diverse Classrooms: Representation, Rights and Resources

    ERIC Educational Resources Information Center

    Stein, Pippa

    2012-01-01

    Multimodal Pedagogies in Diverse Classrooms examines how the classroom can become a democratic space founded on the integration of different histories, modes of representation, feelings, languages and discourses, and is essential reading for anyone interested in the connection between multimodality, pedagogy, democracy and social justice in…

  8. Critical Visual Literacy: Multimodal Communication across the Curriculum

    ERIC Educational Resources Information Center

    Duffelmeyer, Barb Blakely; Ellertson, Anthony

    2005-01-01

    "Critical Visual Literacy: Multimodal Communication Across the Curriculum" makes the case for expanding the pedagogical space and communication possibilities in undergraduate communication-intensive and linked (learning community) courses by allowing students to create multimodal texts that deal with civic and cultural and/or discipline…

  9. Level up with Multimodal Composition in Social Studies

    ERIC Educational Resources Information Center

    Dalton, Bridget

    2015-01-01

    Students find multimodal composing highly engaging. Even with students' investment in designing multimodal texts, the teaching process is complex. The purpose for writing, audience, and genre must be considered in relation to the modes, digital authoring and presentation tools, and technology devices that are available to the composer. This…

  10. Instantiation of Multimodal Semiotic Systems in Science Classroom Discourse

    ERIC Educational Resources Information Center

    Tang, Kok-Sing

    2013-01-01

    Science classroom discourse is inherently multimodal in that scientific meanings are made through an integration of multiple semiotic systems (e.g., language, diagrams, equations). Although some studies have described this multimodal nature, few have examined and explained the relationship between the integration of multiple semiotic systems and…

  11. A Multimodal Discourse Analysis of a Yoruba Song-Drama

    ERIC Educational Resources Information Center

    Olateju, Moji. A.

    2015-01-01

    This paper presents a multimodal discourse analysis of a story that has been turned into a Yoruba song-drama, highlighting the ideational, interpersonal and textual aspects of the song-drama. The data is a short song-drama meant to teach children importunity, determination and hard work through persistence. The multimodal and narrative conventions…

  12. A Multimodal Discourse Analysis of Tmall's Double Eleven Advertisement

    ERIC Educational Resources Information Center

    Hu, Chunyu; Luo, Mengxi

    2016-01-01

    From the 1990s, the multimodal turn in discourse studies makes multimodal discourse analysis a popular topic in linguistics and communication studies. An important approach to applying Systemic Functional Linguistics to non-verbal modes is Visual Grammar initially proposed by Kress and van Leeuwen (1996). Considering that commercial advertisement…

  13. Fracturing Writing Spaces: Multimodal Storytelling Ignites Process Writing

    ERIC Educational Resources Information Center

    Lenters, Kimberly; Winters, Kari-Lynn

    2013-01-01

    In this paper, we explore the affordances of literature-based, arts-infused and digital media processes for students, as multimodal practices take centre stage in an English Language Arts unit on fractured fairy tales. The study takes up the challenge of addressing multimodal literacy instruction and research in ways that utilize a range of…

  14. Multimode-Optical-Fiber Imaging Probe

    NASA Technical Reports Server (NTRS)

    Jackson, Deborah

    2000-01-01

    Currently, endoscopic surgery uses single-mode fiber-bundles to obtain in vivo image information inside orifices of the body. This limits their use to the larger natural bodily orifices and to surgical procedures where there is plenty of room for manipulation. The knee joint, for example can be easily viewed with a fiber optic viewer, but joints in the finger cannot. However, there are a host of smaller orifices where fiber endoscopy would play an important role if a cost effective fiber probe were developed with small enough dimensions (< 250 microns). Examples of beneficiaries of micro-endoscopes are the treatment of the Eustatian tube of the middle ear, the breast ducts, tear ducts, coronary arteries, fallopian tubes, as well as the treatment of salivary duct parotid disease, and the neuro endoscopy of the ventricles and spinal canal. To solve this problem, this work describes an approach for recovering images from. tightly confined spaces using multimode fibers and analytically demonstrates that the concept is sound. The proof of concept draws upon earlier works that concentrated on image recovery after two-way transmission through a multimode fiber as well as work that demonstrated the recovery of images after one-way transmission through a multimode fiber. Both relied on generating a phase conjugated wavefront which was predistorted with the characteristics of the fiber. The described approach also relies on generating a phase conjugated wavefront, but utilizes two fibers to capture the image at some intermediate point (accessible by the fibers, but which is otherwise visually unaccessible).

  15. New developments in multimodal clinical multiphoton tomography

    NASA Astrophysics Data System (ADS)

    König, Karsten

    2011-03-01

    80 years ago, the PhD student Maria Goeppert predicted in her thesis in Goettingen, Germany, two-photon effects. It took 30 years to prove her theory, and another three decades to realize the first two-photon microscope. With the beginning of this millennium, first clinical multiphoton tomographs started operation in research institutions, hospitals, and in the cosmetic industry. The multiphoton tomograph MPTflexTM with its miniaturized flexible scan head became the Prism-Award 2010 winner in the category Life Sciences. Multiphoton tomographs with its superior submicron spatial resolution can be upgraded to 5D imaging tools by adding spectral time-correlated single photon counting units. Furthermore, multimodal hybrid tomographs provide chemical fingerprinting and fast wide-field imaging. The world's first clinical CARS studies have been performed with a hybrid multimodal multiphoton tomograph in spring 2010. In particular, nonfluorescent lipids and water as well as mitochondrial fluorescent NAD(P)H, fluorescent elastin, keratin, and melanin as well as SHG-active collagen have been imaged in patients with dermatological disorders. Further multimodal approaches include the combination of multiphoton tomographs with low-resolution imaging tools such as ultrasound, optoacoustic, OCT, and dermoscopy systems. Multiphoton tomographs are currently employed in Australia, Japan, the US, and in several European countries for early diagnosis of skin cancer (malignant melanoma), optimization of treatment strategies (wound healing, dermatitis), and cosmetic research including long-term biosafety tests of ZnO sunscreen nanoparticles and the measurement of the stimulated biosynthesis of collagen by anti-ageing products.

  16. Multimode-Optical-Fiber Imaging Probe

    NASA Technical Reports Server (NTRS)

    Jackson, Deborah

    2000-01-01

    Currently, endoscopic surgery uses single-mode fiber-bundles to obtain in vivo image information inside orifices of the body. This limits their use to the larger natural bodily orifices and to surgical procedures where there is plenty of room for manipulation. The knee joint, for example can be easily viewed with a fiber optic viewer, but joints in the finger cannot. However, there are a host of smaller orifices where fiber endoscopy would play an important role if a cost effective fiber probe were developed with small enough dimensions (< 250 microns). Examples of beneficiaries of micro-endoscopes are the treatment of the Eustatian tube of the middle ear, the breast ducts, tear ducts, coronary arteries, fallopian tubes, as well as the treatment of salivary duct parotid disease, and the neuro endoscopy of the ventricles and spinal canal. To solve this problem, this work describes an approach for recovering images from. tightly confined spaces using multimode fibers and analytically demonstrates that the concept is sound. The proof of concept draws upon earlier works that concentrated on image recovery after two-way transmission through a multimode fiber as well as work that demonstrated the recovery of images after one-way transmission through a multimode fiber. Both relied on generating a phase conjugated wavefront which was predistorted with the characteristics of the fiber. The described approach also relies on generating a phase conjugated wavefront, but utilizes two fibers to capture the image at some intermediate point (accessible by the fibers, but which is otherwise visually unaccessible).

  17. Multimode entanglement in reconfigurable graph states using optical frequency combs

    NASA Astrophysics Data System (ADS)

    Cai, Y.; Roslund, J.; Ferrini, G.; Arzani, F.; Xu, X.; Fabre, C.; Treps, N.

    2017-06-01

    Multimode entanglement is an essential resource for quantum information processing and quantum metrology. However, multimode entangled states are generally constructed by targeting a specific graph configuration. This yields to a fixed experimental setup that therefore exhibits reduced versatility and scalability. Here we demonstrate an optical on-demand, reconfigurable multimode entangled state, using an intrinsically multimode quantum resource and a homodyne detection apparatus. Without altering either the initial squeezing source or experimental architecture, we realize the construction of thirteen cluster states of various sizes and connectivities as well as the implementation of a secret sharing protocol. In particular, this system enables the interrogation of quantum correlations and fluctuations for any multimode Gaussian state. This initiates an avenue for implementing on-demand quantum information processing by only adapting the measurement process and not the experimental layout.

  18. Multimode entanglement in reconfigurable graph states using optical frequency combs

    PubMed Central

    Cai, Y.; Roslund, J.; Ferrini, G.; Arzani, F.; Xu, X.; Fabre, C.; Treps, N.

    2017-01-01

    Multimode entanglement is an essential resource for quantum information processing and quantum metrology. However, multimode entangled states are generally constructed by targeting a specific graph configuration. This yields to a fixed experimental setup that therefore exhibits reduced versatility and scalability. Here we demonstrate an optical on-demand, reconfigurable multimode entangled state, using an intrinsically multimode quantum resource and a homodyne detection apparatus. Without altering either the initial squeezing source or experimental architecture, we realize the construction of thirteen cluster states of various sizes and connectivities as well as the implementation of a secret sharing protocol. In particular, this system enables the interrogation of quantum correlations and fluctuations for any multimode Gaussian state. This initiates an avenue for implementing on-demand quantum information processing by only adapting the measurement process and not the experimental layout. PMID:28585530

  19. The Role of Multimodal Analgesia in Spine Surgery.

    PubMed

    Kurd, Mark F; Kreitz, Tyler; Schroeder, Gregory; Vaccaro, Alexander R

    2017-04-01

    Optimal postoperative pain control allows for faster recovery, reduced complications, and improved patient satisfaction. Historically, pain management after spine surgery relied heavily on opioid medications. Multimodal regimens were developed to reduce opioid consumption and associated adverse effects. Multimodal approaches used in orthopaedic surgery of the lower extremity, especially joint arthroplasty, have been well described and studies have shown reduced opioid consumption, improved pain and function, and decreased length of stay. A growing body of evidence supports multimodal analgesia in spine surgery. Methods include the use of preemptive analgesia, NSAIDs, the neuromodulatory agents gabapentin and pregabalin, acetaminophen, and extended-action local anesthesia. The development of a standard approach to multimodal analgesia in spine surgery requires extensive assessment of the literature. Because a substantial number of spine surgeries are performed annually, a standardized approach to multimodal analgesia may provide considerable benefits, particularly in the context of the increased emphasis on accountability within the healthcare system.

  20. Coupled spatial multimode solitons in microcavity wires

    NASA Astrophysics Data System (ADS)

    Slavcheva, G.; Gorbach, A. V.; Pimenov, A.

    2016-12-01

    A modal expansion approach is developed and employed to investigate and elucidate the nonlinear mechanism behind the multistability and formation of coupled multimode polariton solitons in microcavity wires. With pump switched on and realistic dissipation parameters, truncating the expansion up to the second-order wire mode, our model predicts two distinct coupled soliton branches: stable and unstable. Modulational stability of the stationary homogeneous solution and soliton branches stability are studied. Our simplified 1D model is in remarkably good agreement with the full 2D mean-field Gross-Pitaevskii model, reproducing correctly the soliton existence domain upon variation of pump amplitude and the onset of multistability.

  1. Sensory Substitution and Multimodal Mental Imagery.

    PubMed

    Nanay, Bence

    2017-09-01

    Many philosophers use findings about sensory substitution devices in the grand debate about how we should individuate the senses. The big question is this: Is "vision" assisted by (tactile) sensory substitution really vision? Or is it tactile perception? Or some sui generis novel form of perception? My claim is that sensory substitution assisted "vision" is neither vision nor tactile perception, because it is not perception at all. It is mental imagery: visual mental imagery triggered by tactile sensory stimulation. But it is a special form of mental imagery that is triggered by corresponding sensory stimulation in a different sense modality, which I call "multimodal mental imagery."

  2. Multimode fiber optic wavelength division multiplexing

    NASA Technical Reports Server (NTRS)

    Spencer, J. L.

    1982-01-01

    Optical wavelength division multiplexing (WDM) systems, with signals transmitted on different wavelengths through a single optical fiber, can have increased bandwidth and fault isolation properties over single wavelength optical systems. Two WDM system designs that might be used with multimode fibers are considered and a general description of the components which could be used to implement the system are given. The components described are sources, multiplexers, demultiplexers, and detectors. Emphasis is given to the demultiplexer technique which is the major developmental component in the WDM system.

  3. Multimodal CARS microscopy of structured carbohydrate biopolymers

    PubMed Central

    Slepkov, Aaron D.; Ridsdale, Andrew; Pegoraro, Adrian F.; Moffatt, Douglas J.; Stolow, Albert

    2010-01-01

    We demonstrate the utility of multimodal coherent anti-Stokes Raman scattering (CARS) microscopy for the study of structured condensed carbohydrate systems. Simultaneous second-harmonic generation (SHG) and spectrally-scanned CARS microscopy was used to elucidate structure, alignment, and density in cellulose cotton fibers and in starch grains undergoing rapid heat-moisture swelling. Our results suggest that CARS response of the O-H stretch region (3000 cm−1–3400 cm−1), together with the commonly-measured C-H stretch (2750 cm−1–2970 cm−1) and SHG provide potentially important structural information and contrast in these materials. PMID:21258555

  4. A novel multimodal CARS miniaturized microscope

    NASA Astrophysics Data System (ADS)

    Smith, Brett; Naji, Majid; Murugkar, Sangeeta; Brideau, Craig; Stys, Peter; Anis, Hanan

    2012-03-01

    We demonstrate the operation of a novel portable, fibre delivery miniaturized multimodal microscope (exoscope) for coherent anti-Stokes Raman scattering and two-photon excitation fluorescence imaging using a single Ti:sapphire femtosecond pulsed laser. This microscope features a large mode area photonic crystal fibre for light delivery, as well as biaxial scanning microelectromechanical system mirrors and custom miniaturized optics corrected for chromatic aberration. We demonstrate imaging of polystyrene beads, two photon excitation fluorescence beads in both forward and backward (epi) directions. This miniaturized exoscope will enable in-vivo imaging of rat spinal cord.

  5. Multimodal Hallucinations in Schizophrenia and Its Management

    PubMed Central

    Kumar, Vijaya; Bagewadi, Virupakshappa; Sagar, Dayanand; Varambally, Shivarama

    2017-01-01

    A cluster of symptoms including hallucinations characterizes schizophrenia. Hallucinations that occur in more than one modality simultaneously and emanate from a single source are called multimodal hallucinations (MMHs). The occurrence of simultaneous hallucinations as the major manifestations of a psychiatric disorder often was dismissed as factitious disorder or malingering. Conversely, MMHs have been reported in severe mental disorders including schizophrenia. Here, we report MMH in two patients of treatment-resistant schizophrenia and its successful management with clozapine. The significance of MMH on the course, prognosis, and treatment resistance of schizophrenia needs to be elucidated. Further systematic research is needed to address these issues. PMID:28250565

  6. Ultrasonic motors using piezoelectric ceramic multimode vibrators.

    PubMed

    Takano, T; Tomikawa, Y; Ogasawara, T; Sugawara, S; Konno, M

    1990-01-01

    The development is reported of an ultrasonic motor using piezoelectric ceramic multimode vibrators consisting of circular or annular plates in which degenerate horizontal vibration modes of the same or different form are used. Two orthogonal nonaxisymmetric vibration modes were used in the same-form case, and the combination of a nonaxisymmetric vibration mode and a radial vibration mode was used in the different-forms case. Some details of the motor design and its experimental characteristics are presented. The ultrasonic motor presented here has a special advantage in its thin construction.

  7. Invariant measures on multimode quantum Gaussian states

    SciTech Connect

    Lupo, C.; Mancini, S.; De Pasquale, A.; Facchi, P.; Florio, G.; Pascazio, S.

    2012-12-15

    We derive the invariant measure on the manifold of multimode quantum Gaussian states, induced by the Haar measure on the group of Gaussian unitary transformations. To this end, by introducing a bipartition of the system in two disjoint subsystems, we use a parameterization highlighting the role of nonlocal degrees of freedom-the symplectic eigenvalues-which characterize quantum entanglement across the given bipartition. A finite measure is then obtained by imposing a physically motivated energy constraint. By averaging over the local degrees of freedom we finally derive the invariant distribution of the symplectic eigenvalues in some cases of particular interest for applications in quantum optics and quantum information.

  8. Cardiac sarcoidosis diagnosed by multimodality imaging.

    PubMed

    Fujikura, Kana; Garcia, Mario J

    2017-09-01

    A 66-year-old woman presented with frequent premature ventricular contractions (PVC) and akinesis of the basal septum on echocardiography. Coronary angiography was normal. Cardiac magnetic resonance showed mid-wall enhancement. Positron emission tomography showed a perfusion defect at the same location using 13N-ammonia, but increased 18-fluorodeoxyglucose uptake. These findings supported the diagnosis of cardiac sarcoidosis. High-dose steroids initially reduced frequency of PVCs but had to be withdrawn due to severe side effects. An ICD was implanted. Our case demonstrates the utility of multimodality imaging to diagnose and guide management of this entity. © 2017, Wiley Periodicals, Inc.

  9. Invariant measures on multimode quantum Gaussian states

    NASA Astrophysics Data System (ADS)

    Lupo, C.; Mancini, S.; De Pasquale, A.; Facchi, P.; Florio, G.; Pascazio, S.

    2012-12-01

    We derive the invariant measure on the manifold of multimode quantum Gaussian states, induced by the Haar measure on the group of Gaussian unitary transformations. To this end, by introducing a bipartition of the system in two disjoint subsystems, we use a parameterization highlighting the role of nonlocal degrees of freedom—the symplectic eigenvalues—which characterize quantum entanglement across the given bipartition. A finite measure is then obtained by imposing a physically motivated energy constraint. By averaging over the local degrees of freedom we finally derive the invariant distribution of the symplectic eigenvalues in some cases of particular interest for applications in quantum optics and quantum information.

  10. Multimodality imaging for resuscitated sudden cardiac death.

    PubMed

    Chen, Yingming Amy; Deva, Djeven; Kirpalani, Anish; Prabhudesai, Vikram; Marcuzzi, Danny W; Graham, John J; Verma, Subodh; Jimenez-Juan, Laura; Yan, Andrew T

    2015-01-01

    We present a case that elegantly illustrates the utility of two novel noninvasive imaging techniques, computed tomography (CT) coronary angiography and cardiac MRI, in the diagnosis and management of a 27-year-old man with exertion-induced cardiac arrest caused by an anomalous right coronary artery. CT coronary angiography with 3D reformatting delineated the interarterial course of an anomalous right coronary artery compressed between the aorta and pulmonary artery, whereas cardiac MRI showed a small myocardial infarction in the right coronary artery territory not detected on echocardiography. This case highlights the value of novel multimodality imaging techniques in the risk stratification and management of patients with resuscitated cardiac arrest.

  11. 300m transmission over multimode fiber at 25Gb/s using a multimode launch at 1310nm.

    PubMed

    Chen, Xin; Bickham, Scott R; Hurley, Jason E; Liu, Hai-Feng; Dosunmu, Olufemi I; Li, Ming-Jun

    2013-11-18

    We demonstrate the transmission of 25Gb/s multimode optical signals over a record length of 300m multimode fiber designed for high modal bandwidth at 1310nm. The power penalty is 1.8 dB at 10(-12) bit error rate level.

  12. Design and installation of a multimode microscopy system

    NASA Astrophysics Data System (ADS)

    Helm, Johannes P.; Haug, Finn-Mogens S.; Storm, Johan F.; Ottersen, Ole-Petter

    2001-04-01

    We describe design and installation of a multi-mode microscopy core facility in an environment of varied research activity in life-sciences. The experimentators can select any combination of a) microscopes (upright, upright fixed-stage, inverted), b) microscopy modes (widefield, DIC, IRDIC, widefield epifluorescence, transmission LSM, reflection and fluorescence CLSM, MPLSM), c) imaging techniques (direct observation, video observation, photography, quantitative camera-recording, flying spot scanning), d) auxiliary systems (equipment for live specimen imaging, electrophysiology, time-coordinated laser-scanning and electrophysiology, patch-clamp). The equipment is installed on one large vibration-isolating optical table (3m X 1.5m X 0.3m). Electronics, auxiliary equipment, and a fiber-coupled, remotely controlled Ar+-Kr+ laser are mounted in a rack system fixed to the ceiling. The design of the shelves allows the head of the CSLM to be moved to any of the microscopes without increasing critical cable lengths. At the same time easy access to all the units is preserved. The beam of a Titanium-Sapphire laser, controlled by means of an EOM and a prism GVD, is coupled directly to the microscopes. Three mirrors mounted on a single precision translation table are integrated into the beam steering system so that the beam can easily be redirected to any of the microscopes. All the available instruments can be operated by the educated and trained user. The system is popular among researchers in neuroanatomy, embryology, cell biology, molecular biology - including the study of protein interactions, e.g. by means of FRET, and electrophysiology. Its colocalization with an EM facility promises to provide considerable synergy effects.

  13. Multimodal biometrics system for efficient human recognition

    NASA Astrophysics Data System (ADS)

    Gupta, Phalguni; Rattani, Ajita; Mehrotra, Hunny; Kaushik, Anil K.

    2006-04-01

    This paper proposes the multimodal biometrics system for identity verification using four traits i.e., face, fingerprint, iris and signature. The proposed system is designed for applications where the training database contains a face, iris, two fingerprint images and/or one or two signature image(s) for each individual. The final decision is made by fusion at "matching score level architecture" in which feature vectors are created independently for query images and are then compared to the enrollment templates which are stored during database preparation for each biometric trait. Based on the proximity of feature vector and template, each subsystem computes its own matching score. These individual scores are finally combined into a total score, which is passed to the decision module. Multimodal system is developed through fusion of face, fingerprint, iris and signature recognition. This system is tested on IITK database and the overall accuracy of the system is found to be more than 97% accurate with FAR and FRR of 2.46% and 1.23% respectively.

  14. Multimodal brain monitoring in fulminant hepatic failure

    PubMed Central

    Paschoal Jr, Fernando Mendes; Nogueira, Ricardo Carvalho; Ronconi, Karla De Almeida Lins; de Lima Oliveira, Marcelo; Teixeira, Manoel Jacobsen; Bor-Seng-Shu, Edson

    2016-01-01

    Acute liver failure, also known as fulminant hepatic failure (FHF), embraces a spectrum of clinical entities characterized by acute liver injury, severe hepatocellular dysfunction, and hepatic encephalopathy. Cerebral edema and intracranial hypertension are common causes of mortality in patients with FHF. The management of patients who present acute liver failure starts with determining the cause and an initial evaluation of prognosis. Regardless of whether or not patients are listed for liver transplantation, they should still be monitored for recovery, death, or transplantation. In the past, neuromonitoring was restricted to serial clinical neurologic examination and, in some cases, intracranial pressure monitoring. Over the years, this monitoring has proven insufficient, as brain abnormalities were detected at late and irreversible stages. The need for real-time monitoring of brain functions to favor prompt treatment and avert irreversible brain injuries led to the concepts of multimodal monitoring and neurophysiological decision support. New monitoring techniques, such as brain tissue oxygen tension, continuous electroencephalogram, transcranial Doppler, and cerebral microdialysis, have been developed. These techniques enable early diagnosis of brain hemodynamic, electrical, and biochemical changes, allow brain anatomical and physiological monitoring-guided therapy, and have improved patient survival rates. The purpose of this review is to discuss the multimodality methods available for monitoring patients with FHF in the neurocritical care setting. PMID:27574545

  15. A Multimodal Theory of Affect Diffusion.

    PubMed

    Peters, Kim; Kashima, Yoshihisa

    2015-09-01

    There is broad consensus in the literature that affect diffuses through social networks (such that a person may "acquire" or "catch" an affective state from his or her social contacts). It is further assumed that affect diffusion primarily occurs as the result of people's tendencies to synchronize their affective actions (such as smiles and frowns). However, as we show, there is a lack of clarity in the literature about the substrate and scope of affect diffusion. One consequence of this is a difficulty in distinguishing between affect diffusion and several other affective influence phenomena that look similar but have very different consequences. There is also a growing body of evidence that action synchrony is unlikely to be the only, or indeed the most important, pathway for affect diffusion. This paper has 2 key aims: (a) to craft a formal definition of affect diffusion that does justice to the core of the phenomenon while distinguishing it from other phenomena with which it is frequently confounded and (b) to advance a theory of the mechanisms of affect diffusion. This theory, which we call the multimodal theory of affect diffusion, identifies 3 parallel multimodal mechanisms that may act as routes for affect diffusion. It also provides a basis for novel predictions about the conditions under which affect is most likely to diffuse. (c) 2015 APA, all rights reserved).

  16. Multimodal EEG Recordings, Psychometrics and Behavioural Analysis.

    PubMed

    Boeijinga, Peter H

    2015-01-01

    High spatial and temporal resolution measurements of neuronal activity are preferably combined. In an overview on how this approach can take shape, multimodal electroencephalography (EEG) is treated in 2 main parts: by experiments without a task and in the experimentally cued working brain. It concentrates first on the alpha rhythm properties and next on data-driven search for patterns such as the default mode network. The high-resolution volumic distributions of neuronal metabolic indices result in distributed cortical regions and possibly relate to numerous nuclei, observable in a non-invasive manner in the central nervous system of humans. The second part deals with paradigms in which nowadays assessment of target-related networks can align level-dependent blood oxygenation, electrical responses and behaviour, taking the temporal resolution advantages of event-related potentials. Evidence-based electrical propagation in serial tasks during performance is now to a large extent attributed to interconnected pathways, particularly chronometry-dependent ones, throughout a chain including a dorsal stream, next ventral cortical areas taking the flow of information towards inferior temporal domains. The influence of aging is documented, and results of the first multimodal studies in neuropharmacology are consistent. Finally a scope on implementation of advanced clinical applications and personalized marker strategies in neuropsychiatry is indicated.

  17. ASIC3 channels in multimodal sensory perception.

    PubMed

    Li, Wei-Guang; Xu, Tian-Le

    2011-01-19

    Acid-sensing ion channels (ASICs), which are members of the sodium-selective cation channels belonging to the epithelial sodium channel/degenerin (ENaC/DEG) family, act as membrane-bound receptors for extracellular protons as well as nonproton ligands. At least five ASIC subunits have been identified in mammalian neurons, which form both homotrimeric and heterotrimeric channels. The highly proton sensitive ASIC3 channels are predominantly distributed in peripheral sensory neurons, correlating with their roles in multimodal sensory perception, including nociception, mechanosensation, and chemosensation. Different from other ASIC subunit composing ion channels, ASIC3 channels can mediate a sustained window current in response to mild extracellular acidosis (pH 7.3-6.7), which often occurs accompanied by many sensory stimuli. Furthermore, recent evidence indicates that the sustained component of ASIC3 currents can be enhanced by nonproton ligands including the endogenous metabolite agmatine. In this review, we first summarize the growing body of evidence for the involvement of ASIC3 channels in multimodal sensory perception and then discuss the potential mechanisms underlying ASIC3 activation and mediation of sensory perception, with a special emphasis on its role in nociception. We conclude that ASIC3 activation and modulation by diverse sensory stimuli represent a new avenue for understanding the role of ASIC3 channels in sensory perception. Furthermore, the emerging implications of ASIC3 channels in multiple sensory dysfunctions including nociception allow the development of new pharmacotherapy.

  18. Multimodal communication by captive chimpanzees (Pan troglodytes)

    PubMed Central

    Russell, Jamie L.; Hopkins, William D.

    2009-01-01

    Many studies have shown that apes and monkeys are adept at cross-modal matching tasks requiring the subject to identify objects in one modality when information regarding those objects has been presented in a different modality. However, much less is known about non-human primates’ production of multimodal signaling in communicative contexts. Here, we present evidence from a study of 110 chimpanzees demonstrating that they select the modality of communication in accordance with variations in the attentional focus of a human interactant, which is consistent with previous research. In each trial, we presented desirable food to one of two chimpanzees, turning mid-way through the trial from facing one chimpanzee to facing the other chimpanzee, and documented their communicative displays, as the experimenter turned towards or away from the subjects. These chimpanzees varied their signals within a context-appropriate modality, displaying a range of different visual signals when a human experimenter was facing them and a range of different auditory or tactile (attention-getting) signals when the human was facing away from them; this finding extends previous research on multimodal signaling in this species. Thus, in the impoverished circumstances characteristic of captivity, complex signaling tactics are nevertheless exhibited by chimpanzees, suggesting continuity in intersubjective psychological processes in humans and apes. PMID:19504272

  19. Anatomy and efficiency of urban multimodal mobility

    PubMed Central

    Gallotti, Riccardo; Barthelemy, Marc

    2014-01-01

    The growth of transportation networks and their increasing interconnections, although positive, has the downside effect of an increasing complexity which make them difficult to use, to assess, and limits their efficiency. On average in the UK, 23% of travel time is lost in connections for trips with more than one mode, and the lack of synchronization decreases very slowly with population size. This lack of synchronization between modes induces differences between the theoretical quickest trip and the ‘time-respecting' path, which takes into account waiting times at interconnection nodes. We analyse here the statistics of these paths on the multilayer, temporal network of the entire, multimodal british public transportation system. We propose a statistical decomposition – the ‘anatomy' – of trips in urban areas, in terms of riding, waiting and walking times, and which shows how the temporal structure of trips varies with distance and allows us to compare different cities. Weaknesses in systems can be either insufficient transportation speed or service frequency, but the key parameter controlling their global efficiency is the total number of stop events per hour for all modes. This analysis suggests the need for better optimization strategies, adapted to short, long unimodal or multimodal trips. PMID:25371238

  20. Ten unanswered questions in multimodal communication.

    PubMed

    Partan, Sarah R

    2013-01-01

    The study of multimodal communication has become an active and vibrant field. This special issue of Behavioral Ecology and Sociobiology brings together new developments in this rapidly expanding area. In this final contribution to the special issue, I look to the future and discuss ten questions in need of further work, touching on issues ranging from theoretical modeling and the evolution of behavior to molecular mechanisms and the development of behavior. In particular, I emphasize that the use of multimodal communication allows animals to switch between sensory channels when one channel becomes too noisy, and suggest that a better understanding of this process may help us both to understand the evolution of multisensory signaling and to predict the success of species facing environmental changes that affect signaling channels, such as urbanization and climate change. An expanded section is included on the effects of climate change on animal communication across sensory channels, urging researchers to pursue this topic due to the rapidity with which the environment is currently transforming.

  1. Multimodal approach to seismic pavement testing

    USGS Publications Warehouse

    Ryden, N.; Park, C.B.; Ulriksen, P.; Miller, R.D.

    2004-01-01

    A multimodal approach to nondestructive seismic pavement testing is described. The presented approach is based on multichannel analysis of all types of seismic waves propagating along the surface of the pavement. The multichannel data acquisition method is replaced by multichannel simulation with one receiver. This method uses only one accelerometer-receiver and a light hammer-source, to generate a synthetic receiver array. This data acquisition technique is made possible through careful triggering of the source and results in such simplification of the technique that it is made generally available. Multiple dispersion curves are automatically and objectively extracted using the multichannel analysis of surface waves processing scheme, which is described. Resulting dispersion curves in the high frequency range match with theoretical Lamb waves in a free plate. At lower frequencies there are several branches of dispersion curves corresponding to the lower layers of different stiffness in the pavement system. The observed behavior of multimodal dispersion curves is in agreement with theory, which has been validated through both numerical modeling and the transfer matrix method, by solving for complex wave numbers. ?? ASCE / JUNE 2004.

  2. A multimodal behavioral approach to performance anxiety.

    PubMed

    Lazarus, Arnold A; Abramovitz, Arnold

    2004-08-01

    Cognitive-behavior therapy (CBT) stresses a trimodal assessment framework (affect, behavior, and cognition [ABC]), whereas the multimodal approach assesses seven discrete but interactive components--behavior, affect, sensation, imagery, cognition, interpersonal relationships, and drugs/biological factors (BASIC I.D.). Only complex or recalcitrant cases call for the entire seven-pronged range of multimodal interventions. Various case illustrations are offered as examples of how a clinician might proceed when confronted with problems that fall under the general heading of performance anxiety. The main example is of a violinist in a symphony orchestra whose career was in serious jeopardy because of his extreme fear of performing in public. He responded very well to a focused but elaborate desensitization procedure. The hierarchy that was eventually constructed contained many dimensions and subhierarchies featuring interlocking elements that evoked his anxiety. In addition to imaginal systematic desensitization, sessions were devoted to his actual performance in the clinical setting. As a homework assignment, he found it helpful to listen to a long-playing record of an actual rehearsal and to play along with the world-renowned orchestra and conductor. The subsequent disclosure by the client of an important sexual problem was dealt with concomitantly by using a fairly conventional counseling procedure. Therapy required 20 sessions over a 3-month period.

  3. Quantitative multi-modal NDT data analysis

    SciTech Connect

    Heideklang, René; Shokouhi, Parisa

    2014-02-18

    A single NDT technique is often not adequate to provide assessments about the integrity of test objects with the required coverage or accuracy. In such situations, it is often resorted to multi-modal testing, where complementary and overlapping information from different NDT techniques are combined for a more comprehensive evaluation. Multi-modal material and defect characterization is an interesting task which involves several diverse fields of research, including signal and image processing, statistics and data mining. The fusion of different modalities may improve quantitative nondestructive evaluation by effectively exploiting the augmented set of multi-sensor information about the material. It is the redundant information in particular, whose quantification is expected to lead to increased reliability and robustness of the inspection results. There are different systematic approaches to data fusion, each with its specific advantages and drawbacks. In our contribution, these will be discussed in the context of nondestructive materials testing. A practical study adopting a high-level scheme for the fusion of Eddy Current, GMR and Thermography measurements on a reference metallic specimen with built-in grooves will be presented. Results show that fusion is able to outperform the best single sensor regarding detection specificity, while retaining the same level of sensitivity.

  4. Multimodal oscillations in systems with strong contraction

    NASA Astrophysics Data System (ADS)

    Medvedev, Georgi; Yoo, Yun

    2007-04-01

    One- and two-parameter families of flows in R3 near an Andronov-Hopf bifurcation (AHB) are investigated in this work. We identify conditions on the global vector field, which yield a rich family of multimodal orbits passing close to a weakly unstable saddle-focus and perform a detailed asymptotic analysis of the trajectories in the vicinity of the saddle-focus. Our analysis covers both cases of sub- and supercritical AHB. For the supercritical case, we find that the periodic orbits born from the AHB are bimodal when viewed in the frame of coordinates generated by the linearization about the bifurcating equilibrium. If the AHB is subcritical, it is accompanied by the appearance of multimodal orbits, which consist of long series of nearly harmonic oscillations separated by large amplitude spikes. We analyze the dependence of the interspike intervals (which can be extremely long) on the control parameters. In particular, we show that the interspike intervals grow logarithmically as the boundary between regions of sub- and supercritical AHB is approached in the parameter space. We also identify a window of complex and possibly chaotic oscillations near the boundary between the regions of sub- and supercritical AHB and explain the mechanism generating these oscillations. This work is motivated by the numerical results for a finite-dimensional approximation of a free boundary problem modeling solid fuel combustion.

  5. Visual tracking for multi-modality computer-assisted image guidance

    NASA Astrophysics Data System (ADS)

    Basafa, Ehsan; Foroughi, Pezhman; Hossbach, Martin; Bhanushali, Jasmine; Stolka, Philipp

    2017-03-01

    With optical cameras, many interventional navigation tasks previously relying on EM, optical, or mechanical guidance can be performed robustly, quickly, and conveniently. We developed a family of novel guidance systems based on wide-spectrum cameras and vision algorithms for real-time tracking of interventional instruments and multi-modality markers. These navigation systems support the localization of anatomical targets, support placement of imaging probe and instruments, and provide fusion imaging. The unique architecture - low-cost, miniature, in-hand stereo vision cameras fitted directly to imaging probes - allows for an intuitive workflow that fits a wide variety of specialties such as anesthesiology, interventional radiology, interventional oncology, emergency medicine, urology, and others, many of which see increasing pressure to utilize medical imaging and especially ultrasound, but have yet to develop the requisite skills for reliable success. We developed a modular system, consisting of hardware (the Optical Head containing the mini cameras) and software (components for visual instrument tracking with or without specialized visual features, fully automated marker segmentation from a variety of 3D imaging modalities, visual observation of meshes of widely separated markers, instant automatic registration, and target tracking and guidance on real-time multi-modality fusion views). From these components, we implemented a family of distinct clinical and pre-clinical systems (for combinations of ultrasound, CT, CBCT, and MRI), most of which have international regulatory clearance for clinical use. We present technical and clinical results on phantoms, ex- and in-vivo animals, and patients.

  6. Performance evaluation of similarity measures for dense multimodal stereovision

    NASA Astrophysics Data System (ADS)

    Yaman, Mustafa; Kalkan, Sinan

    2016-05-01

    Multimodal imaging systems have recently been drawing attention in fields such as medical imaging, remote sensing, and video surveillance systems. In such systems, estimating depth has become possible due to the promising progress of multimodal matching techniques. We perform a systematic performance evaluation of similarity measures frequently used in the literature for dense multimodal stereovision. The evaluated measures include mutual information (MI), sum of squared distances, normalized cross-correlation, census transform, local self-similarity (LSS) as well as descriptors adopted to multimodal settings, like scale invariant feature transform (SIFT), speeded-up robust features (SURF), histogram of oriented gradients (HOG), binary robust independent elementary features, and fast retina keypoint (FREAK). We evaluate the measures over datasets we generated, compiled, and provided as a benchmark and compare the performances using the Winner Takes All method. The datasets are (1) synthetically modified four popular pairs from the Middlebury Stereo Dataset (namely, Tsukuba, Venus, Cones, and Teddy) and (2) our own multimodal image pairs acquired using the infrared and the electro-optical cameras of a Kinect device. The results show that MI and HOG provide promising results for multimodal imagery, and FREAK, SURF, SIFT, and LSS can be considered as alternatives depending on the multimodality level and the computational complexity requirements of the intended application.

  7. Towards an intelligent framework for multimodal affective data analysis.

    PubMed

    Poria, Soujanya; Cambria, Erik; Hussain, Amir; Huang, Guang-Bin

    2015-03-01

    An increasingly large amount of multimodal content is posted on social media websites such as YouTube and Facebook everyday. In order to cope with the growth of such so much multimodal data, there is an urgent need to develop an intelligent multi-modal analysis framework that can effectively extract information from multiple modalities. In this paper, we propose a novel multimodal information extraction agent, which infers and aggregates the semantic and affective information associated with user-generated multimodal data in contexts such as e-learning, e-health, automatic video content tagging and human-computer interaction. In particular, the developed intelligent agent adopts an ensemble feature extraction approach by exploiting the joint use of tri-modal (text, audio and video) features to enhance the multimodal information extraction process. In preliminary experiments using the eNTERFACE dataset, our proposed multi-modal system is shown to achieve an accuracy of 87.95%, outperforming the best state-of-the-art system by more than 10%, or in relative terms, a 56% reduction in error rate.

  8. Multimodal Task-Driven Dictionary Learning for Image Classification.

    PubMed

    Bahrampour, Soheil; Nasrabadi, Nasser M; Ray, Asok; Jenkins, William Kenneth

    2016-01-01

    Dictionary learning algorithms have been successfully used for both reconstructive and discriminative tasks, where an input signal is represented with a sparse linear combination of dictionary atoms. While these methods are mostly developed for single-modality scenarios, recent studies have demonstrated the advantages of feature-level fusion based on the joint sparse representation of the multimodal inputs. In this paper, we propose a multimodal task-driven dictionary learning algorithm under the joint sparsity constraint (prior) to enforce collaborations among multiple homogeneous/heterogeneous sources of information. In this task-driven formulation, the multimodal dictionaries are learned simultaneously with their corresponding classifiers. The resulting multimodal dictionaries can generate discriminative latent features (sparse codes) from the data that are optimized for a given task such as binary or multiclass classification. Moreover, we present an extension of the proposed formulation using a mixed joint and independent sparsity prior, which facilitates more flexible fusion of the modalities at feature level. The efficacy of the proposed algorithms for multimodal classification is illustrated on four different applications--multimodal face recognition, multi-view face recognition, multi-view action recognition, and multimodal biometric recognition. It is also shown that, compared with the counterpart reconstructive-based dictionary learning algorithms, the task-driven formulations are more computationally efficient in the sense that they can be equipped with more compact dictionaries and still achieve superior performance.

  9. Magnetic field sensing based on magnetic-fluid-clad multimode-singlemode-multimode fiber structures.

    PubMed

    Tang, Jiali; Pu, Shengli; Dong, Shaohua; Luo, Longfeng

    2014-10-14

    Magnetic field sensing based on magnetic-fluid-clad multimode-singlemode- multimode fiber structures is proposed and experimentalized. The structures are fabricated out using fiber fusion splicing techniques. The sensing principle is based on the interference between the core mode and cladding modes. Two interference dips are observed in our spectral range. Experimental results indicate that the magnetic field sensing sensitivities of 215 pm/mT and 0.5742 dB/mT are obtained for interference dip around 1595 nm. For interference dip around 1565 nm, the sensitivities are 60.5 pm/mT and 0.4821 dB/mT. The response of temperature is also investigated. The temperature sensitivity for the dip around 1595 nm is obtained to be 9.93 pm/°C.

  10. In vivo multimodal nonlinear optical imaging of mucosal tissue

    NASA Astrophysics Data System (ADS)

    Sun, Ju; Shilagard, Tuya; Bell, Brent; Motamedi, Massoud; Vargas, Gracie

    2004-05-01

    We present a multimodal nonlinear imaging approach to elucidate microstructures and spectroscopic features of oral mucosa and submucosa in vivo. The hamster buccal pouch was imaged using 3-D high resolution multiphoton and second harmonic generation microscopy. The multimodal imaging approach enables colocalization and differentiation of prominent known spectroscopic and structural features such as keratin, epithelial cells, and submucosal collagen at various depths in tissue. Visualization of cellular morphology and epithelial thickness are in excellent agreement with histological observations. These results suggest that multimodal nonlinear optical microscopy can be an effective tool for studying the physiology and pathology of mucosal tissue.

  11. Fano resonances in prism-coupled multimode square micropillar resonators

    NASA Astrophysics Data System (ADS)

    Lee, Ho-Tong; Zhou, Linjie; Poon, Andrew W.

    2005-06-01

    We report Fano resonances in a multimode square glass micropillar resonator; the resonances were obtained by using angle-resolved prism coupling. Our experiments reveal characteristically asymmetric line shapes of high-Q resonances and of detuned low-Q resonances in multimode reflection spectra. The asymmetric resonance line shapes evolve for an approximately pi phase within a 0.5° range of reflection angles. We model our observed asymmetric multimode resonances by the far-field interference between a light wave that is evanescently coupled with a high-Q mode orbit and a coherent light wave that is refractively coupled with a detuned low-Q mode orbit.

  12. Multi-modality molecular imaging for gastric cancer research

    NASA Astrophysics Data System (ADS)

    Liang, Jimin; Chen, Xueli; Liu, Junting; Hu, Hao; Qu, Xiaochao; Wang, Fu; Nie, Yongzhan

    2011-12-01

    Because of the ability of integrating the strengths of different modalities and providing fully integrated information, multi-modality molecular imaging techniques provide an excellent solution to detecting and diagnosing earlier cancer, which remains difficult to achieve by using the existing techniques. In this paper, we present an overview of our research efforts on the development of the optical imaging-centric multi-modality molecular imaging platform, including the development of the imaging system, reconstruction algorithms and preclinical biomedical applications. Primary biomedical results show that the developed optical imaging-centric multi-modality molecular imaging platform may provide great potential in the preclinical biomedical applications and future clinical translation.

  13. Investigation on a compact in-line multimode-single-mode-multimode fiber structure

    NASA Astrophysics Data System (ADS)

    Yin, Bin; Li, Yang; Liu, Zhi-bo; Feng, Suchun; Bai, Yunlong; Xu, Yao; Jian, Shuisheng

    2016-06-01

    We carried out a detailed investigation on a compact in-line multimode single-mode multimode (MSM) fiber structure. Both theoretical modal and experimental setup were established to demonstrate the transmission characteristics and the corresponding responses of the applied strain and temperature. The proposed structure simply involves a section of the single-mode fiber (SMF) spliced to two sections of multimode fiber (MMF) and lead-in and lead-out SMFs. The excited environment-sensitive cladding modes together with the fundamental mode in the central SMF form a typical Mach-Zehnder interferometer (MZI). We analyzed the transmission characteristics of the different length of the middle SMF and the MMF in detail. In the experiment, we obtained the extinction ratio of the MSM fiber structure based MZI comb spectrum which was up to 20 dB, and sensitivities of 0.7096 pm/με (0-2000 με) and 44.12 pm/°C (10-70 °C), which proved the potential sensing applications of the proposed fiber structure.

  14. Multimodal Protein Constructs for Herbivore Insect Control

    PubMed Central

    Sainsbury, Frank; Benchabane, Meriem; Goulet, Marie-Claire; Michaud, Dominique

    2012-01-01

    Transgenic plants expressing combinations of microbial or plant pesticidal proteins represent a promising tool for the efficient, durable control of herbivorous insects. In this review we describe current strategies devised for the heterologous co-expression of pesticidal proteins in planta, some of which have already shown usefulness in plant protection. Emphasis is placed on protein engineering strategies involving the insertion of single DNA constructs within the host plant genome. Multimodal fusion proteins integrating complementary pesticidal functions along a unique polypeptide are first considered, taking into account the structural constraints associated with protein or protein domain grafting to biologically active proteins. Strategies that allow for the co- or post-translational release of two or more pesticidal proteins are then considered, including polyprotein precursors releasing free proteins upon proteolytic cleavage, and multicistronic transcripts for the parallel translation of single protein-encoding mRNA sequences. PMID:22822457

  15. Interactive multi-mode blade impact analysis

    NASA Technical Reports Server (NTRS)

    Alexander, A.; Cornell, R. W.

    1978-01-01

    The theoretical methodology used in developing an analysis for the response of turbine engine fan blades subjected to soft-body (bird) impacts is reported, and the computer program developed using this methodology as its basis is described. This computer program is an outgrowth of two programs that were previously developed for the purpose of studying problems of a similar nature (a 3-mode beam impact analysis and a multi-mode beam impact analysis). The present program utilizes an improved missile model that is interactively coupled with blade motion which is more consistent with actual observations. It takes into account local deformation at the impact area, blade camber effects, and the spreading of the impacted missile mass on the blade surface. In addition, it accommodates plate-type mode shapes. The analysis capability in this computer program represents a significant improvement in the development of the methodology for evaluating potential fan blade materials and designs with regard to foreign object impact resistance.

  16. Disentangling multimodal processes in social categorization.

    PubMed

    Slepian, Michael L

    2015-03-01

    The current work examines the role of sensorimotor processes (manipulating whether visual exposure to hard and soft stimuli encourage sensorimotor simulation) and metaphor processes (assessing whether participants have understanding of a pertinent metaphor: "hard" Republicans and "soft" Democrats) in social categorization. Using new methodology to disassociate these multimodal processes (i.e., semantic, metaphoric, and sensorimotoric), the current work demonstrates that both sensorimotor and metaphor processes, combined, are needed to find an effect upon conceptual processing, providing evidence in support of the combined importance of these two theorized components. When participants comprehended the metaphor of hard Republicans and soft Democrats, and when encouraged to simulate sensorimotor experiences of hard and soft stimuli, those stimuli influenced categorization of faces as Republican and Democrat.

  17. Bimodal and multimodal plant biomass particle mixtures

    DOEpatents

    Dooley, James H.

    2013-07-09

    An industrial feedstock of plant biomass particles having fibers aligned in a grain, wherein the particles are individually characterized by a length dimension (L) aligned substantially parallel to the grain, a width dimension (W) normal to L and aligned cross grain, and a height dimension (H) normal to W and L, wherein the L.times.H dimensions define a pair of substantially parallel side surfaces characterized by substantially intact longitudinally arrayed fibers, the W.times.H dimensions define a pair of substantially parallel end surfaces characterized by crosscut fibers and end checking between fibers, and the L.times.W dimensions define a pair of substantially parallel top and bottom surfaces, and wherein the particles in the feedstock are collectively characterized by having a bimodal or multimodal size distribution.

  18. Multimodality Imaging Findings of a Renal Aspergilloma

    PubMed Central

    Bulakçı, Mesut; Kartal, Merve Gülbiz; Çelenk, Erhan; Tunçer, Sena; Kılıçaslan, Işın

    2016-01-01

    Background Renal aspergillosis is a rare infection that usually occurs in persons with a predisposition for this condition. Its differential diagnosis includes primary and metastatic renal malignancies, pyelonephritis and secondary abscess formation, granulomatous disorders, and renal infarction. We aim to stress the role of multimodality imaging and percutaneous biopsy in the diagnosis of this condition. Case Report We present diffusion weighted imaging (DWI) and positron emission tomography-computed tomography (PET-CT) findings in addition to conventional imaging modalities in a 55-year-old man with secondary renal aspergilloma. Conclusion Radiological imaging methods are an integral part of diagnostic workup for renal aspergillosis. A definitive diagnosis is made by histopathological and/or microbiological examination of the material obtained via percutaneous biopsy under guidance of imaging methods. PMID:27994929

  19. Multimodal sensing: enhanced functionality with data compression

    NASA Astrophysics Data System (ADS)

    Krishna, Sanjay

    2010-04-01

    The past decade has seen a dramatic development in the infrared imaging systems. New material systems, novel fabrication schemes and creative read out circuit and system designs have all driven the third generation systems towards large format focal plane arrays with multicolor capability and high operating temperature. This paper explores the possibility of development of next generation infrared imagers. Could it be a bio-inspired infrared retina similar to the human eye? The conjecture is that the next generation systems will have two distinctive features that is present in the eye. They are (a) the ability to sense multimodal information including spectral, polarization, dynamic range, phase and (b) the intelligence to only send only small pieces of information to the central processing unit.

  20. Portable, miniaturized, fibre delivered, multimodal CARS exoscope.

    PubMed

    Smith, Brett; Naji, Majid; Murugkar, Sangeeta; Alarcon, Emilio; Brideau, Craig; Stys, Peter; Anis, Hanan

    2013-07-15

    We demonstrate for the first time, a portable multimodal coherent anti-Stokes Raman scattering microscope (exoscope) for minimally invasive in-vivo imaging of tissues. This device is based around a micro-electromechanical system scanning mirror and miniaturized optics with light delivery accomplished by a photonic crystal fibre. A single Ti:sapphire femtosecond pulsed laser is used as the light source to produce CARS, two photon excitation fluorescence and second harmonic generation images. The high resolution and distortion-free images obtained from various resolution and bio-samples, particularly in backward direction (epi) successfully demonstrate proof of concept, and pave the path towards future non or minimally-invasive in vivo imaging.

  1. Managing hyperemesis gravidarum: a multimodal challenge.

    PubMed

    Jueckstock, J K; Kaestner, R; Mylonas, I

    2010-07-15

    Up to 90% of pregnant women experience nausea and vomiting. When prolonged or severe, this is known as hyperemesis gravidarum (HG), which can, in individual cases, be life threatening. In this article the aetiology, diagnosis and treatment strategies will be presented based on a selective literature review. Treatment strategies range from outpatient dietary advice and antiemetic drugs to hospitalization and intravenous (IV) fluid replacement in persistent or severe cases. Alternative methods, such as acupuncture, are not yet evidence based but sometimes have a therapeutic effect.In most cases, the condition is self limiting and subsides by around 20 weeks gestation. More severe forms require medical intervention once other organic causes of nausea and vomiting have been excluded. In addition, a psychosomatic approach is often helpful.In view of its potential complexity, general practitioners and obstetricians should be well informed about HG and therapy should be multimodal.

  2. TDRS multimode transponder program. Phase 1: Design

    NASA Technical Reports Server (NTRS)

    Cnossen, R. S.

    1972-01-01

    The use of geosynchronous tracking and data relay satellites (TDRS) which can serve both low data rate users at VHF and high data rate users at other frequencies is considered. The effects of radio frequency interference from the earth and of multipath propagation due to reflections from the earth are expected to pose problems for the TDRS system at VHF. Investigations suggest several modulation techniques that offer promise to overcome these problems. This report provides a complete design of a VHF/UHF multimode transponder and its associated ground support equipment. The transponder is designed for installation aboard an aircraft and will demonstrate candidate modulation techniques to provide the required information for the design of an eventual VHF/UHF transponder suitable for installation in a user satellite, capable of operating as part of a TDRS system.

  3. Multimodal event streams for virtual reality

    NASA Astrophysics Data System (ADS)

    von Spiczak, J.; Samset, E.; DiMaio, S.; Reitmayr, G.; Schmalstieg, D.; Burghart, C.; Kikinis, R.

    2007-01-01

    Applications in the fields of virtual and augmented reality as well as image-guided medical applications make use of a wide variety of hardware devices. Existing frameworks for interconnecting low-level devices and high-level application programs do not exploit the full potential for processing events coming from arbitrary sources and are not easily generalizable. In this paper, we will introduce a new multi-modal event processing methodology using dynamically-typed event attributes for event passing between multiple devices and systems. The existing OpenTracker framework was modified to incorporate a highly flexible and extensible event model, which can store data that is dynamically created and arbitrarily typed at runtime. The main factors impacting the library's throughput were determined and the performance was shown to be sufficient for most typical applications. Several sample applications were developed to take advantage of the new dynamic event model provided by the library, thereby demonstrating its flexibility and expressive power.

  4. The multimodal treatment of eating disorders

    PubMed Central

    HALMI, KATHERINE A.

    2005-01-01

    The treatment of eating disorders is based on a multimodal model, recognizing that these disorders do not have a single cause or a predictable course. The treatment strategy is determined by the severity of illness and the specific eating disorder diagnosis. For the treatment of anorexia nervosa, the key elements are medical management, behavioral therapy, cognitive therapy and family therapy, while pharmacotherapy is at best an adjunct to other therapies. In bulimia nervosa, the treatment of choice is cognitive-behavioral therapy, but a greater improvement in mood and anxiety occurs when antidepressant therapy is added. In binge eating disorder, cognitive-behavioral therapy and interpersonal therapy produce substantial and long-lasting changes and pharmacological treatment has often a useful role. PMID:16633511

  5. Multimodal device for assessment of skin malformations

    NASA Astrophysics Data System (ADS)

    Bekina, A.; Garancis, V.; Rubins, U.; Spigulis, J.; Valeine, L.; Berzina, A.

    2013-11-01

    A variety of multi-spectral imaging devices is commercially available and used for skin diagnostics and monitoring; however, an alternative cost-efficient device can provide an advanced spectral analysis of skin. A compact multimodal device for diagnosis of pigmented skin lesions was developed and tested. A polarized LED light source illuminates the skin surface at four different wavelengths - blue (450 nm), green (545 nm), red (660 nm) and infrared (940 nm). Spectra of reflected light from the 25 mm wide skin spot are imaged by a CMOS sensor. Four spectral images are obtained for mapping of the main skin chromophores. The specific chromophore distribution differences between different skin malformations were analyzed and information of subcutaneous structures was consecutively extracted.

  6. Temporal Multimode Storage of Entangled Photon Pairs

    NASA Astrophysics Data System (ADS)

    Tiranov, Alexey; Strassmann, Peter C.; Lavoie, Jonathan; Brunner, Nicolas; Huber, Marcus; Verma, Varun B.; Nam, Sae Woo; Mirin, Richard P.; Lita, Adriana E.; Marsili, Francesco; Afzelius, Mikael; Bussières, Félix; Gisin, Nicolas

    2016-12-01

    Multiplexed quantum memories capable of storing and processing entangled photons are essential for the development of quantum networks. In this context, we demonstrate and certify the simultaneous storage and retrieval of two entangled photons inside a solid-state quantum memory and measure a temporal multimode capacity of ten modes. This is achieved by producing two polarization-entangled pairs from parametric down-conversion and mapping one photon of each pair onto a rare-earth-ion-doped (REID) crystal using the atomic frequency comb (AFC) protocol. We develop a concept of indirect entanglement witnesses, which can be used as Schmidt number witnesses, and we use it to experimentally certify the presence of more than one entangled pair retrieved from the quantum memory. Our work puts forward REID-AFC as a platform compatible with temporal multiplexing of several entangled photon pairs along with a new entanglement certification method, useful for the characterization of multiplexed quantum memories.

  7. Automatic processing of multimodal tomography datasets.

    PubMed

    Parsons, Aaron D; Price, Stephen W T; Wadeson, Nicola; Basham, Mark; Beale, Andrew M; Ashton, Alun W; Mosselmans, J Frederick W; Quinn, Paul D

    2017-01-01

    With the development of fourth-generation high-brightness synchrotrons on the horizon, the already large volume of data that will be collected on imaging and mapping beamlines is set to increase by orders of magnitude. As such, an easy and accessible way of dealing with such large datasets as quickly as possible is required in order to be able to address the core scientific problems during the experimental data collection. Savu is an accessible and flexible big data processing framework that is able to deal with both the variety and the volume of data of multimodal and multidimensional scientific datasets output such as those from chemical tomography experiments on the I18 microfocus scanning beamline at Diamond Light Source.

  8. Hardware-accelerated multimodality volume fusion

    NASA Astrophysics Data System (ADS)

    Hong, Helen; Bae, Juhee; Kye, Heewon; Shin, Yeong-Gil

    2005-04-01

    In this paper, we propose a novel technique of multimodality volume fusion using a graphics hardware. Our 3D texture based volume fusion algorithm consists of three steps: First, two volumes of different modalities are loaded into the texture memory in the GPU. Second, textured slices of two volumes along the same proxy geometry are combined with various compositing functions. Third, all the composited slices are alpha blended. We have implemented our algorithm using HLSL (High Level Shader Language). Our method shows that the exact depth of each volume and the realistic views with interactive rate in comparison with the software-based image integration. Experimental results using MR and PET brain images and the angiography with a stent show that over composting operation is more useful for clinical application.

  9. Automatic processing of multimodal tomography datasets

    PubMed Central

    Parsons, Aaron D.; Price, Stephen W. T.; Wadeson, Nicola; Basham, Mark; Beale, Andrew M.; Ashton, Alun W.; Mosselmans, J. Frederick. W.; Quinn, Paul. D.

    2017-01-01

    With the development of fourth-generation high-brightness synchrotrons on the horizon, the already large volume of data that will be collected on imaging and mapping beamlines is set to increase by orders of magnitude. As such, an easy and accessible way of dealing with such large datasets as quickly as possible is required in order to be able to address the core scientific problems during the experimental data collection. Savu is an accessible and flexible big data processing framework that is able to deal with both the variety and the volume of data of multimodal and multidimensional scientific datasets output such as those from chemical tomography experiments on the I18 microfocus scanning beamline at Diamond Light Source. PMID:28009564

  10. Multimodal interfaces with voice and gesture input

    SciTech Connect

    Milota, A.D.; Blattner, M.M.

    1995-07-20

    The modalities of speech and gesture have different strengths and weaknesses, but combined they create synergy where each modality corrects the weaknesses of the other. We believe that a multimodal system such a one interwining speech and gesture must start from a different foundation than ones which are based solely on pen input. In order to provide a basis for the design of a speech and gesture system, we have examined the research in other disciplines such as anthropology and linguistics. The result of this investigation was a taxonomy that gave us material for the incorporation of gestures whose meanings are largely transparent to the users. This study describes the taxonomy and gives examples of applications to pen input systems.

  11. Condensation of thresholds in multimode microlasers

    NASA Astrophysics Data System (ADS)

    Ge, Li; Cao, Hui; Stone, A. Douglas

    2017-02-01

    We show from ab initio laser theory that by choosing an appropriate spatial pump profile, many different spatial modes of a typical microlaser can be turned on at the same pump energy, substantially increasing the number N of simultaneous lasing modes. The optimal pump profile can be obtained simply from knowledge of the space-dependent saturated gain profile when the system is uniformly pumped up to the N th modal threshold. We test this general result by applying it to a two-dimensional diffusive random laser and a microdisk laser. Achieving highly multimode lasing at reasonable pump powers is useful for reducing the spatial coherence of laser sources, making them suitable for use in speckle-free imaging and other applications.

  12. Image registration techniques for multimodal sensors

    NASA Astrophysics Data System (ADS)

    Altinalev, Tevfik; Cetin, Enis A.; Yardimci, Yasemin C.

    2002-08-01

    Image registration refers to the problem of spatially aligning two or more images. A challenging problem in this area is the registration of images obtained by different types of sensors. In general such images have different gray level characteristics and commonly used techniques such as those based on area correlations cannot be applied directly. On the other hand, contours representing the region boundaries are preserved in most cases. Therefore, contour based registration techniques are applicable to multimodal sensors. In this paper, various registration techniques based on subband decomposition and projection along x and y directions are introduced. The effect of binarization is investigated. Unknown translation and scaling parameters are computed using cross-correlation methods over the projections. Performance of the algorithms is compared.

  13. Robust temporal alignment of multimodal cardiac sequences

    NASA Astrophysics Data System (ADS)

    Perissinotto, Andrea; Queirós, Sandro; Morais, Pedro; Baptista, Maria J.; Monaghan, Mark; Rodrigues, Nuno F.; D'hooge, Jan; Vilaça, João. L.; Barbosa, Daniel

    2015-03-01

    Given the dynamic nature of cardiac function, correct temporal alignment of pre-operative models and intraoperative images is crucial for augmented reality in cardiac image-guided interventions. As such, the current study focuses on the development of an image-based strategy for temporal alignment of multimodal cardiac imaging sequences, such as cine Magnetic Resonance Imaging (MRI) or 3D Ultrasound (US). First, we derive a robust, modality-independent signal from the image sequences, estimated by computing the normalized cross-correlation between each frame in the temporal sequence and the end-diastolic frame. This signal is a resembler for the left-ventricle (LV) volume curve over time, whose variation indicates different temporal landmarks of the cardiac cycle. We then perform the temporal alignment of these surrogate signals derived from MRI and US sequences of the same patient through Dynamic Time Warping (DTW), allowing to synchronize both sequences. The proposed framework was evaluated in 98 patients, which have undergone both 3D+t MRI and US scans. The end-systolic frame could be accurately estimated as the minimum of the image-derived surrogate signal, presenting a relative error of 1.6 +/- 1.9% and 4.0 +/- 4.2% for the MRI and US sequences, respectively, thus supporting its association with key temporal instants of the cardiac cycle. The use of DTW reduces the desynchronization of the cardiac events in MRI and US sequences, allowing to temporally align multimodal cardiac imaging sequences. Overall, a generic, fast and accurate method for temporal synchronization of MRI and US sequences of the same patient was introduced. This approach could be straightforwardly used for the correct temporal alignment of pre-operative MRI information and intra-operative US images.

  14. Preterm EEG: a multimodal neurophysiological protocol.

    PubMed

    Stjerna, Susanna; Voipio, Juha; Metsäranta, Marjo; Kaila, Kai; Vanhatalo, Sampsa

    2012-02-18

    Since its introduction in early 1950s, electroencephalography (EEG) has been widely used in the neonatal intensive care units (NICU) for assessment and monitoring of brain function in preterm and term babies. Most common indications are the diagnosis of epileptic seizures, assessment of brain maturity, and recovery from hypoxic-ischemic events. EEG recording techniques and the understanding of neonatal EEG signals have dramatically improved, but these advances have been slow to penetrate through the clinical traditions. The aim of this presentation is to bring theory and practice of advanced EEG recording available for neonatal units. In the theoretical part, we will present animations to illustrate how a preterm brain gives rise to spontaneous and evoked EEG activities, both of which are unique to this developmental phase, as well as crucial for a proper brain maturation. Recent animal work has shown that the structural brain development is clearly reflected in early EEG activity. Most important structures in this regard are the growing long range connections and the transient cortical structure, subplate. Sensory stimuli in a preterm baby will generate responses that are seen at a single trial level, and they have underpinnings in the subplate-cortex interaction. This brings neonatal EEG readily into a multimodal study, where EEG is not only recording cortical function, but it also tests subplate function via different sensory modalities. Finally, introduction of clinically suitable dense array EEG caps, as well as amplifiers capable of recording low frequencies, have disclosed multitude of brain activities that have as yet been overlooked. In the practical part of this video, we show how a multimodal, dense array EEG study is performed in neonatal intensive care unit from a preterm baby in the incubator. The video demonstrates preparation of the baby and incubator, application of the EEG cap, and performance of the sensory stimulations.

  15. Rethinking Resources: Multimodal Pedagogies in the ESL Classroom.

    ERIC Educational Resources Information Center

    Stein, Pippa

    2000-01-01

    Describes a process for rethinking resources in the English-as-a-Second-Language classroom. Rethinking resources is possible through multimodal pedagogies that recognize students as remakers and transformers of the representational resources available to them. (Author/VWL)

  16. Reliability-Based Decision Fusion in Multimodal Biometric Verification Systems

    NASA Astrophysics Data System (ADS)

    Kryszczuk, Krzysztof; Richiardi, Jonas; Prodanov, Plamen; Drygajlo, Andrzej

    2007-12-01

    We present a methodology of reliability estimation in the multimodal biometric verification scenario. Reliability estimation has shown to be an efficient and accurate way of predicting and correcting erroneous classification decisions in both unimodal (speech, face, online signature) and multimodal (speech and face) systems. While the initial research results indicate the high potential of the proposed methodology, the performance of the reliability estimation in a multimodal setting has not been sufficiently studied or evaluated. In this paper, we demonstrate the advantages of using the unimodal reliability information in order to perform an efficient biometric fusion of two modalities. We further show the presented method to be superior to state-of-the-art multimodal decision-level fusion schemes. The experimental evaluation presented in this paper is based on the popular benchmarking bimodal BANCA database.

  17. Manifold learning based registration algorithms applied to multimodal images.

    PubMed

    Azampour, Mohammad Farid; Ghaffari, Aboozar; Hamidinekoo, Azam; Fatemizadeh, Emad

    2014-01-01

    Manifold learning algorithms are proposed to be used in image processing based on their ability in preserving data structures while reducing the dimension and the exposure of data structure in lower dimension. Multi-modal images have the same structure and can be registered together as monomodal images if only structural information is shown. As a result, manifold learning is able to transform multi-modal images to mono-modal ones and subsequently do the registration using mono-modal methods. Based on this application, in this paper novel similarity measures are proposed for multi-modal images in which Laplacian eigenmaps are employed as manifold learning algorithm and are tested against rigid registration of PET/MR images. Results show the feasibility of using manifold learning as a way of calculating the similarity between multimodal images.

  18. Three-dimensional multimodal image-guidance for neurosurgery

    SciTech Connect

    Peters, T.; Munger, P.; Comeau, R.; Evans, A.; Olivier, A.; Davey, B.

    1996-04-01

    The authors address the use of multimodality imaging as an aid to the planning and guidance of neurosurgical procedures, and discuss the integration of anatomical (CT and MRI), vascular (DSA), and functional (PET) data for presentation to the surgeon during surgery. The workstation is an enhancement of a commercially available system, and in addition to the guidance offered via a hand-held probe, it incorporates the use of multimodality imaging and adds enhanced realism to the surgeon through the use of a stereoscopic three-dimensional (3-D) image display. The probe may be visualized stereoscopically in single or multimodality images. The integration of multimodality data in this manner provides the surgeon with a complete overview of brain structures on which he is performing surgery, or through which he is passing probes or cannulas, enabling him to avoid critical vessels and/or structures of functional significance.

  19. Rethinking Resources: Multimodal Pedagogies in the ESL Classroom.

    ERIC Educational Resources Information Center

    Stein, Pippa

    2000-01-01

    Describes a process for rethinking resources in the English-as-a-Second-Language classroom. Rethinking resources is possible through multimodal pedagogies that recognize students as remakers and transformers of the representational resources available to them. (Author/VWL)

  20. Towards a compact fiber laser for multimodal imaging

    NASA Astrophysics Data System (ADS)

    Nie, Bai; Saytashev, Ilyas; Dantus, Marcos

    2014-03-01

    We report on multimodal depth-resolved imaging of unstained living Drosophila Melanogaster larva using sub-50 fs pulses centered at 1060 nm wavelength. Both second harmonic and third harmonic generation imaging modalities are demonstrated.

  1. 2016 SmartWay Multimodal Carrier Tool Demonstration

    EPA Pesticide Factsheets

    This EPA presentation provides information on the SmartWay Transport Partnership Multimodal Tool; carrier categories, emission metrics, performance reports, completing the tool, data collection and usage, and the 2016 schedule.

  2. Participatory Classification in a System for Assessing Multimodal Transportation Patterns

    DTIC Science & Technology

    2015-02-17

    potential problem on new users. The aggregated classifiers can be used to bootstrap at the initial stage of the classification . However, ongoing collection...Participatory Classification in a System for Assessing Multimodal Transportation Patterns Kalyanaraman Shankari Mogeng Yin Randy H. Katz David E...Participatory Classification in a System for Assessing Multimodal Transportation Patterns 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT

  3. A Single-Photon Subtractor for Multimode Quantum States

    NASA Astrophysics Data System (ADS)

    Ra, Young-Sik; Jacquard, Clément; Averchenko, Valentin; Roslund, Jonathan; Cai, Yin; Dufour, Adrien; Fabre, Claude; Treps, Nicolas

    2016-05-01

    In the last decade, single-photon subtraction has proved to be key operations in optical quantum information processing and quantum state engineering. Implementation of the photon subtraction has been based on linear optics and single-photon detection on single-mode resources. This technique, however, becomes unsuitable with multimode resources such as spectrally multimode squeezed states or continuous variables cluster states. We implement a single-photon subtractor for such multimode resources based on sum-frequency generation and single-photon detection. An input multimode quantum state interacts with a bright control beam whose spectrum has been engineered through ultrafast pulse-shaping. The multimode quantum state resulting from the single-photon subtractor is analyzed with multimode homodyne detection whose local oscillator spectrum is independently engineered. We characterize the single-photon subtractor via coherent-state quantum process tomography, which provides its mode-selectivity and subtraction modes. The ability to simultaneously control the state engineering and its detection ensures both flexibility and scalability in the production of highly entangled non-Gaussian quantum states.

  4. Teleportation of continuous variable multimode Greeberger Horne Zeilinger entangled states

    NASA Astrophysics Data System (ADS)

    He, Guangqiang; Zhang, Jingtao; Zeng, Guihua

    2008-11-01

    Quantum teleportation protocols of continuous variable (CV) Greeberger-Horne-Zeilinger (GHZ) and Einstein-Podolsky-Rosen (EPR) entangled states are proposed, and are generalized to teleportation of arbitrary multimode GHZ entangled states described by Van Loock and Braunstein (2000 Phys. Rev. Lett. 84 3482). Each mode of a multimode entangled state is teleported using a CV EPR entangled pair and classical communication. The analytical expression of fidelity for the multimode Gaussian states which evaluates the teleportation quality is presented. The analytical results show that the fidelity is a function of both the squeezing parameter r, which characterizes the multimode entangled state to be teleported, and the channel parameter p, which characterizes the EPR pairs shared by Alice and Bob. The fidelity increases with increasing p, but decreases with increasing r, i.e., it is more difficult to teleport the more perfect multimode entangled states. The entanglement degree of the teleported multimode entangled states increases with increasing both r and p. In addition, the fact is proved that our teleportation protocol of EPR entangled states using parallel EPR pairs as quantum channels is the best case of the protocol using four-mode entangled states (Adhikari et al 2008 Phys. Rev. A 77 012337).

  5. Two-photon excitation endoscopy through a multimode optical fiber

    NASA Astrophysics Data System (ADS)

    Morales Delgado, Edgar E.; Psaltis, Demetri; Moser, Christophe

    2016-03-01

    The vast number of propagating solutions to the wave equation in multimode optical fibers represents a larger information capacity than provided by fiber bundles of the same diameter. Therefore, in the field of imaging, multimode fibers potentially allow the transmission of images with higher resolution. However, image transmission through multimode fibers is not direct as in the fiber bundle case, in which each of the fiber cores can relay a portion of the distal image. In multimode fiber transmission, a distribution of intensity is scrambled in time and space by the propagating modes, leading to a speckle-like pattern that does not resemble the initial distribution. Here, we demonstrate two-photon excitation imaging of fluorescent beads through a multimode optical fiber. We show that our method maintains the advantages of two-photon excitation microscopy compared to single-photon excitation such as reduced photo-bleaching, deeper penetration depth and sectioning capability. Our method is based on time-gated digital phase conjugation, which allows the generation of focused pulses on the other side of a multimode fiber. To acquire an image, the focused femtosecond pulse is scanned in a three-dimensional mesh, producing two-photon excitation on each spatial location of the sample. By collecting the fluorescence through the fiber, a 3D two-photon image is reconstructed.

  6. Mode coupling in multimode plastic optical fiber

    NASA Astrophysics Data System (ADS)

    Wang, Jing

    1999-10-01

    In this thesis, we report the results of our experimental and theoretical studies of mode coupling in multi-mode optical fibers. We demonstrate that strong mode coupling in poly(methyl methacrylate) (PMMA) based multi-mode plastic optical fibers (POFs) effectively increases the bandwidth performance by a factor of as much as an order of magnitude. We investigate in detail the physical mechanisms of mode coupling. The most important feature of an optical fiber waveguide is its bandwidth, which defines its information carrying capacity. A major limitation on the bandwidth of multi- mode glass and plastic optical fibers is modal dispersion, in which different optical modes propagate at different velocities and the dispersion grows linearly with length. Modal dispersion in an optical fiber waveguide is reduced through mode coupling by allowing the energy packets of a signal pulse at different times to occupy different modes as they are propagating down the waveguide. With mode coupling, pulse broadening varies only as a characteristic square root function of the fiber length as opposed to following the usual linear dependence The bandwidths of both step index (SI) and graded index (GI) POF samples are carefully measured in the time domain and determined to be 80 +/- 10 MHz per 100m for SI POF and 3.0 +/- 0.4 GHz per 100m for GI POF. The index profiles are first directly measured by standard high accuracy techniques, such as the near field method, the refracted near field ray method, and the transverse interferometric method (TIM), and then probed with the highly sensitive differential mode delay (DMD) measurement. We developed a highly efficient numerical methodology based on the Streifer-Kurtz WKB theory for solving the scalar wave equation in fiber waveguides and implemented the new method in MathematicaTM to simulate fiber optical transmission characteristics for an arbitrary given index profile, such as the DMD profile, impulse response, and bandwidth performance

  7. Variations in the Use of Perioperative Multimodal Analgesic Therapy.

    PubMed

    Ladha, Karim S; Patorno, Elisabetta; Huybrechts, Krista F; Liu, Jun; Rathmell, James P; Bateman, Brian T

    2016-04-01

    Practice guidelines for perioperative pain management recommend that multimodal analgesic therapy should be used for all postsurgical patients. However, the proportion of patients who actually receive this evidence-based approach is unknown. The objective of this study was to describe hospital-level patterns in the utilization of perioperative multimodal analgesia. Data for the study were obtained from the Premier Research Database. Patients undergoing below-knee amputation, open lobectomy, total knee arthroplasty, and open colectomy between 2007 and 2014 were included in the analysis. Patients were considered to have multimodal therapy if they received one or more nonopioid analgesic therapies. Mixed-effects logistic regression models were used to estimate the hospital-specific frequency of multimodal therapy use while adjusting for the case mix of patients and hospital characteristics and accounting for random variation. The cohort consisted of 799,449 patients who underwent a procedure at 1 of 315 hospitals. The mean probability of receiving multimodal therapy was 90.4%, with 95% of the hospitals having a predicted probability between 42.6 and 99.2%. A secondary analysis examined whether patients received two or more nonopioid analgesics, which gave an average predicted probability of 54.2%, with 95% of the hospitals having a predicted probability between 9.3 and 93.2%. In this large nationwide sample of surgical admissions in the United States, the authors observed tremendous variation in the utilization of multimodal therapy not accounted for by patient or hospital characteristics. Efforts should be made to identify why there are variations in the use of multimodal analgesic therapy and to promote its adoption in appropriate patients.

  8. Variations in the Use of Perioperative Multimodal Analgesic Therapy

    PubMed Central

    Ladha, Karim S.; Patorno, Elisabetta; Huybrechts, Krista F.; Liu, Jun; Rathmell, James P.; Bateman, Brian T.

    2016-01-01

    Objective Practice guidelines for perioperative pain management recommend that multimodal analgesic therapy should be used for all post-surgical patients. However, the proportion of patients whom actually receive this evidence-based approach is currently unknown. The objective of this study was to describe hospital-level patterns in the utilization of perioperative multimodal analgesia. Methods Data for the study were obtained from the Premier Research Database. Patients undergoing below-knee amputation, open lobectomy, total knee arthroplasty and open colectomy between 2007 and 2014 were included in the analysis. Patients were considered to have multimodal therapy if they received one or more non-opioid analgesic therapies. Mixed-effects logistic regression models were used to estimate the hospital-specific frequency of multimodal therapy use while adjusting for the case-mix of patients and hospital characteristics and accounting for random variation. Results The cohort consisted of 799,449 patients who underwent a procedure at one of 315 hospitals. The mean probability of receiving multimodal therapy was 90.4%, with 95% of the hospitals having a predicted probability between 42.6% and 99.2%. In a secondary analysis, we examined whether patients received two or more non-opioid analgesics, which gave an average predicted probability of 54.2%, with 95% of the hospitals having a predicted probability between 9.3% and 93.2%. Conclusion In this large nationwide sample of surgical admissions in the United States we observed tremendous variation in the utilization of multimodal therapy use not accounted for by patient or hospital characteristics. Efforts should be made to identify why there are variations in the use of multimodal analgesic therapy and to promote its adoption in appropriate patients. PMID:26835644

  9. Feature matching evaluation for multimodal correspondence

    NASA Astrophysics Data System (ADS)

    Gesto-Diaz, M.; Tombari, F.; Gonzalez-Aguilera, D.; Lopez-Fernandez, L.; Rodriguez-Gonzalvez, P.

    2017-07-01

    This paper proposes a study and evaluation of approaches aimed at image matching under different modalities, together with a survey of methodologies used for performance comparison in this specific context, and, finally, a novel algorithm for image matching. First, a new dataset is introduced to overcome the limitations of existing datasets, which includes modalities such as visible, thermal, intensity and depth images. This dataset is used to compare the state of the art of feature detectors and descriptors. Template matching techniques commonly used to carry out multimodal correspondence are also adapted and compared therein. In total, 28 different combinations of detectors and descriptors are evaluated. In addition, the detectors' repeatability and the assessment of matching results based on Receiving Operating Characteristic (ROC) curve associated to all tested detector-descriptor combinations are presented, highlighting the best performing pairs. Finally, a novel Adaptive Pairwise Matching (APM) algorithm created to improve the robustness of matching towards outliers is also proposed and tested within our evaluation framework.

  10. Haptic-Multimodal Flight Control System Update

    NASA Technical Reports Server (NTRS)

    Goodrich, Kenneth H.; Schutte, Paul C.; Williams, Ralph A.

    2011-01-01

    The rapidly advancing capabilities of autonomous aircraft suggest a future where many of the responsibilities of today s pilot transition to the vehicle, transforming the pilot s job into something akin to driving a car or simply being a passenger. Notionally, this transition will reduce the specialized skills, training, and attention required of the human user while improving safety and performance. However, our experience with highly automated aircraft highlights many challenges to this transition including: lack of automation resilience; adverse human-automation interaction under stress; and the difficulty of developing certification standards and methods of compliance for complex systems performing critical functions traditionally performed by the pilot (e.g., sense and avoid vs. see and avoid). Recognizing these opportunities and realities, researchers at NASA Langley are developing a haptic-multimodal flight control (HFC) system concept that can serve as a bridge between today s state of the art aircraft that are highly automated but have little autonomy and can only be operated safely by highly trained experts (i.e., pilots) to a future in which non-experts (e.g., drivers) can safely and reliably use autonomous aircraft to perform a variety of missions. This paper reviews the motivation and theoretical basis of the HFC system, describes its current state of development, and presents results from two pilot-in-the-loop simulation studies. These preliminary studies suggest the HFC reshapes human-automation interaction in a way well-suited to revolutionary ease-of-use.

  11. Nanosecond laser damage of optical multimode fibers

    NASA Astrophysics Data System (ADS)

    Mann, Guido; Krüger, Jörg

    2016-07-01

    For pulse laser materials processing often optical step index and gradient index multimode fibers with core diameters ranging from 100 to 600 μm are used. The design of a high power fiber transmission system must take into account limitations resulting from both surface and volume damage effects. Especially, breakdown at the fiber end faces and selffocusing in the fiber volume critically influence the fiber performance. At least operation charts are desirable to select the appropriate fiber type for given laser parameters. In industry-relevant studies the influence of fiber core diameter and end face preparation on laser-induced (surface) damage thresholds (LIDT) was investigated for frequently used all-silica fiber types (manufacturer LEONI). Experiments on preform material (initial fiber material) and compact specimens (models of the cladding and coating material) accompanied the tests performed in accordance with the relevant LIDT standards ISO 21254-1 and ISO 21254-2 for 1-on-1 and S-on-1 irradiation conditions, respectively. The relation beam diameter vs. LIDT was investigated for fused silica fibers. Additionally, laser-induced (bulk) damage thresholds of fused silica preform material F300 (manufacturer Heraeus) in dependence on external mechanical stress simulating fiber bending were measured. All experiments were performed with 10-ns laser pulses at 1064 and 532 nm wavelength with a Gaussian beam profile.

  12. Multimodal entity coreference for cervical dysplasia diagnosis.

    PubMed

    Song, Dezhao; Kim, Edward; Huang, Xiaolei; Patruno, Joseph; Munoz-Avila, Hector; Heflin, Jeff; Long, L Rodney; Antani, Sameer

    2015-01-01

    Cervical cancer is the second most common type of cancer for women. Existing screening programs for cervical cancer, such as Pap Smear, suffer from low sensitivity. Thus, many patients who are ill are not detected in the screening process. Using images of the cervix as an aid in cervical cancer screening has the potential to greatly improve sensitivity, and can be especially useful in resource-poor regions of the world. In this paper, we develop a data-driven computer algorithm for interpreting cervical images based on color and texture. We are able to obtain 74% sensitivity and 90% specificity when differentiating high-grade cervical lesions from low-grade lesions and normal tissue. On the same dataset, using Pap tests alone yields a sensitivity of 37% and specificity of 96%, and using HPV test alone gives a 57% sensitivity and 93% specificity. Furthermore, we develop a comprehensive algorithmic framework based on Multimodal Entity Coreference for combining various tests to perform disease classification and diagnosis. When integrating multiple tests, we adopt information gain and gradient-based approaches for learning the relative weights of different tests. In our evaluation, we present a novel algorithm that integrates cervical images, Pap, HPV, and patient age, which yields 83.21% sensitivity and 94.79% specificity, a statistically significant improvement over using any single source of information alone.

  13. Practical applications of multimodal NDT data

    NASA Astrophysics Data System (ADS)

    Frankle, Robert S.

    1993-01-01

    Today's powerful computer workstations enable multimodal nondestructive testing (NDT) to be used for such practical applications as detecting and evaluating defects in structures. Radiography (x ray) and ultrasonics (UT) are examples of two different nondestructive tests, or modalities, which measure characteristics of materials and structures without affecting them. Traditionally, NDT produced an analog result, such as an image on x-ray film, which was difficult to review, interpret, and store. New and more powerful digital NDT techniques, such as industrial x-ray computed tomography (CT), produce digital output that is readily amenable to computerized analysis and storage. Computers are now available with sufficient memory and performance to support interactive processing of digital NDT data sets, which can easily exceed 100 megabytes. Numerous data sets can be stored on small, inexpensive tape cassettes. Failure Analysis Associates, Inc. (FaAA) has developed software-based techniques for using NDT to identify defects in structures. These techniques are also used to visualize the NDT data and to analyze the structural integrity of parts containing NDT-detected defects. FaAA's approach employs state-of-the-art scientific visualization and computer workstation technology. For some types of materials, such as advanced composites, data from different NDT modalities are needed to locate different types of defects. Applications of this technology include assessment of impact damage in composite aerospace structures, investigation of failed assemblies, and evaluation of metallic casting defects.

  14. Multimodal interaction for human-robot teams

    NASA Astrophysics Data System (ADS)

    Burke, Dustin; Schurr, Nathan; Ayers, Jeanine; Rousseau, Jeff; Fertitta, John; Carlin, Alan; Dumond, Danielle

    2013-05-01

    Unmanned ground vehicles have the potential for supporting small dismounted teams in mapping facilities, maintaining security in cleared buildings, and extending the team's reconnaissance and persistent surveillance capability. In order for such autonomous systems to integrate with the team, we must move beyond current interaction methods using heads-down teleoperation which require intensive human attention and affect the human operator's ability to maintain local situational awareness and ensure their own safety. This paper focuses on the design, development and demonstration of a multimodal interaction system that incorporates naturalistic human gestures, voice commands, and a tablet interface. By providing multiple, partially redundant interaction modes, our system degrades gracefully in complex environments and enables the human operator to robustly select the most suitable interaction method given the situational demands. For instance, the human can silently use arm and hand gestures for commanding a team of robots when it is important to maintain stealth. The tablet interface provides an overhead situational map allowing waypoint-based navigation for multiple ground robots in beyond-line-of-sight conditions. Using lightweight, wearable motion sensing hardware either worn comfortably beneath the operator's clothing or integrated within their uniform, our non-vision-based approach enables an accurate, continuous gesture recognition capability without line-of-sight constraints. To reduce the training necessary to operate the system, we designed the interactions around familiar arm and hand gestures.

  15. Multimode bolometer development for the PIXIE instrument

    NASA Astrophysics Data System (ADS)

    Nagler, Peter C.; Crowley, Kevin T.; Denis, Kevin L.; Devasia, Archana M.; Fixsen, Dale J.; Kogut, Alan J.; Manos, George; Porter, Scott; Stevenson, Thomas R.

    2016-07-01

    The Primordial Inflation Explorer (PIXIE) is an Explorer-class mission concept designed to measure the polar- ization and absolute intensity of the cosmic microwave background. In the following, we report on the design, fabrication, and performance of the multimode polarization-sensitive bolometers for PIXIE, which are based on silicon thermistors. In particular we focus on several recent advances in the detector design, including the implementation of a scheme to greatly raise the frequencies of the internal vibrational modes of the large-area, low-mass optical absorber structure consisting of a grid of micromachined, ion-implanted silicon wires. With ˜ 30 times the absorbing area of the spider-web bolometers used by Planck, the tensioning scheme enables the PIXIE bolometers to be robust in the vibrational and acoustic environment at launch of the space mission. More generally, it could be used to reduce microphonic sensitivity in other types of low temperature detectors. We also report on the performance of the PIXIE bolometers in a dark cryogenic environment.

  16. Multimode Bolometer Development for the PIXIE Instrument

    NASA Technical Reports Server (NTRS)

    Nagler, Peter C.; Crowley, Kevin T.; Denis, Kevin L.; Devasia, Archana M.; Fixsen, Dale J.; Kogut, Alan J.; Manos, George; Porter, Scott; Stevenson, Thomas R.

    2016-01-01

    The Primordial Inflation Explorer (PIXIE) is an Explorer-class mission concept designed to measure the polarization and absolute intensity of the cosmic microwave background. In the following, we report on the design, fabrication, and performance of the multimode polarization-sensitive bolometers for PIXIE, which are based on silicon thermistors. In particular we focus on several recent advances in the detector design, including the implementation of a scheme to greatly raise the frequencies of the internal vibrational modes of the large-area, low-mass optical absorber structure consisting of a grid of micromachined, ion-implanted silicon wires. With approximately 30 times the absorbing area of the spider-web bolometers used by Planck, the tensioning scheme enables the PIXIE bolometers to be robust in the vibrational and acoustic environment at launch of the space mission. More generally, it could be used to reduce microphonic sensitivity in other types of low temperature detectors. We also report on the performance of the PIXIE bolometers in a dark cryogenic environment.

  17. Normalized entropy measure for multimodality image alignment

    NASA Astrophysics Data System (ADS)

    Studholme, Colin; Hawkes, David J.; Hill, Derek L.

    1998-06-01

    Automated multi-modality 3D medical image alignment has been an active area of research for many years. There have been a number of recent papers proposing and investigating the use of entropy derived measures of brain image alignment. Any registration measure must allow us to choose between transformation estimates based on the similarity of images within their volume of overlap. Since 3D medical images often have a limited extent and overlap, the similarity measure for the two transformation estimates may be derived from two very different regions within the images. Direct measures of information such as the joint entropy and mutual information will therefore be a function of, not only image similarity in the region of overlap, but also of the local image content within the overlap. In this paper we present a new measure, normalized mutual information, which is simply the ratio of the sum of the marginal entropies and the joint entropy. The effect of changing overlap on current entropy measures and this normalized measure are compared using a simple image model and experiments on clinical MR-PET and MR-CT image data. Results indicate that the normalized entropy measure provides significantly improved behavior over a range of imaged fields of view.

  18. Multimodal imaging system for dental caries detection

    NASA Astrophysics Data System (ADS)

    Liang, Rongguang; Wong, Victor; Marcus, Michael; Burns, Peter; McLaughlin, Paul

    2007-02-01

    Dental caries is a disease in which minerals of the tooth are dissolved by surrounding bacterial plaques. A caries process present for some time may result in a caries lesion. However, if it is detected early enough, the dentist and dental professionals can implement measures to reverse and control caries. Several optical, nonionized methods have been investigated and used to detect dental caries in early stages. However, there is not a method that can singly detect the caries process with both high sensitivity and high specificity. In this paper, we present a multimodal imaging system that combines visible reflectance, fluorescence, and Optical Coherence Tomography (OCT) imaging. This imaging system is designed to obtain one or more two-dimensional images of the tooth (reflectance and fluorescence images) and a three-dimensional OCT image providing depth and size information of the caries. The combination of two- and three-dimensional images of the tooth has the potential for highly sensitive and specific detection of dental caries.

  19. Pain Management in Pregnancy: Multimodal Approaches

    PubMed Central

    Shah, Shalini; Banh, Esther T.; Koury, Katharine; Bhatia, Gaurav; Nandi, Roneeta; Gulur, Padma

    2015-01-01

    Nonobstetrical causes of pain during pregnancy are very common and can be incapacitating if not treated appropriately. Recent reports in the literature show that a significant percentage of pregnant women are treated with opioids during pregnancy. To address common pain conditions that present during pregnancy and the available pharmacological and nonpharmacological treatment options, for each of the pain conditions identified, a search using MEDLINE, PubMed, Embase, and Cochrane databases was performed. The quality of the evidence was evaluated in the context of study design. This paper is a narrative summary of the results obtained from individual reviews. There were significant disparities in the studies in terms of design, research and methodology, and outcomes analyzed. There is reasonable evidence available for pharmacological approaches; however, these are also associated with adverse events. Evidence for nonpharmacological approaches is limited and hence their efficacy is unclear, although they do appear to be primarily safe. A multimodal approach using a combination of nonpharmacological and pharmacological options to treat these pain conditions is likely to have the most benefit while limiting risk. Research trials with sound methodology and analysis of outcome data are needed. PMID:26448875

  20. Multimodal pore formation in calcium phosphate cements.

    PubMed

    Lodoso-Torrecilla, Irene; van Gestel, Nicole A P; Diaz-Gomez, Luis; Grosfeld, Eline-Claire; Laperre, Kjell; Wolke, Joop G C; Smith, Brandon T; Arts, Jacobus J; Mikos, AntoniosG; Jansen, John A; Hofmann, Sandra; van den Beucken, Jeroen J J P

    2017-09-23

    Calcium phosphate cements (CPCs) are commonly used as bone substitute materials. However, their slow degradation rate and lack of macroporosity hinders new bone formation. Poly(DL-lactic-co-glycolic acid) (PLGA) incorporation is of great interest as, upon degradation, produces acidic by-products that enhance CPC degradation. Yet, new bone formation is delayed until PLGA degradation occurs a few weeks after implantation. Therefore, the aim of this study was to accelerate the early stage pore formation within CPCs in vitro. With that purpose, we incorporated the water-soluble porogen sucrose at different weight percentages (10 or 20 wt.%) to CPC and CPC/PLGA composites. The results revealed that incorporation of sucrose porogens increased mass loss within the first week of in vitro degradation in groups containing sucrose compared to control groups. After week 1, a further mass loss was observed related to PLGA and CPC degradation. Macroporosity analysis confirmed that macroporosity formation is influenced by the dissolution of sucrose at an early stage and by the degradation of PLGA and CPC at a later stage. We concluded that the combination of sucrose and PLGA porogens in CPC is a promising approach to promote early stage bone tissue ingrowth and complete replacement of CPC via multimodal pore formation. This article is protected by copyright. All rights reserved. © 2017 Wiley Periodicals, Inc.

  1. Multimodal pediatric pain management (part 2).

    PubMed

    Friedrichsdorf, Stefan J

    2017-01-20

    Dr Stefan Friedrichsdorf speaks to Commissioning Editor Jade Parker: Stefan Friedrichsdorf, MD, is medical director of the Department of Pain Medicine, Palliative Care and Integrative Medicine at Children's Hospitals and Clinics of Minnesota in Minneapolis/St Paul, MN, USA, home to one of the largest and most comprehensive programs of its kind in the country. The pain and palliative care program is devoted to control acute, chronic/complex and procedural pain for inpatients and outpatients in close collaboration with all pediatric subspecialties at Children's Minnesota. The team also provides holistic, interdisciplinary care for children and teens with life limiting or terminal diseases and their families. Integrative medicine provides and teaches integrative, nonpharmacological therapies (such as massage, acupuncture/acupressure, biofeedback, aromatherapy and self-hypnosis) to provide care that promotes optimal health and supports the highest level of functioning in all individual children's activities. In this second part of the interview they discuss multimodal (opioid-sparing) analgesia for hospitalized children in pain and how analgesics and adjuvant medications, interventions, rehabilitation, psychological and integrative therapies act synergistically for more effective pediatric pain control with fewer side effects than a single analgesic or modality.

  2. Fluorescent magnetic hybrid nanoprobe for multimodal bioimaging

    PubMed Central

    Bright, Vanessa

    2011-01-01

    A fluorescent magnetic hybrid imaging nanoprobe (HINP) was fabricated by conjugation of superparamagnetic Fe3O4 nanoparticles and visible light-emitting (~600 nm) fluorescent CdTe/CdS quantum dots (QDs). The assembly strategy used the covalent linking of the oxidized dextran shell of magnetic particles to the glutathione ligands of QDs. Synthesized HINP formed stable water-soluble colloidal dispersions. The structure and properties of the particles were characterized by transmission electron and atomic force microscopy, energy dispersive X-ray analysis and inductively coupled plasma optical emission spectroscopy, dynamic light scattering analysis, optical absorption and photoluminescence spectroscopy, and fluorescent imaging. The luminescence imaging region of the nanoprobe was extended to the near-infrared (NIR) (~800 nm) by conjugation of superparamagnetic nanoparticles with synthesized CdHgTe/CdS QDs. Cadmium, mercury based QDs in HINP can be easily replaced by novel water soluble glutathione stabilized AgInS2/ZnS QDs to present a new class of cadmium-free multimodal imaging agents. Observed NIR photoluminescence of fluorescent magnetic nanocomposites supports their use for bioimaging. The developed HINP provides dual-imaging channels for simultaneous optical and magnetic resonance imaging. PMID:21597146

  3. Monomolecular multimodal fluorescence-radioisotope imaging agents.

    PubMed

    Zhang, Zongren; Liang, Kexian; Bloch, Sharon; Berezin, Mikhail; Achilefu, Samuel

    2005-01-01

    Diagnosis of diseases by different imaging methods can provide complementary information about the functional status of diseased tissues or organs. To overcome the current difficulties in coregistering images from different imaging modalities with a high degree of accuracy, we prepared near-infrared (NIR) monomolecular multimodal imaging agents (MOMIAs) consisting of a heptamethine carbocyanine and 111In-DOTA chelate that served as antennae for optical and scintigraphic imaging, respectively. Their spectral properties clearly show that coordination of indium to MOMIA increased the fluorescence intensity of the compounds. The MOMIAs are exceptionally stable in biological media and serum up to 24 h at 37 degrees C. Biodistribution of the compounds in mice obtained by fluorescence photon and gamma-counts demonstrated a similar distribution trend of the molecular probe in different tissues, suggesting that the detected fluorescence and gamma-emissions emanated from the same source (MOMIA). At 24 h postinjection, the MOMIAs were excreted by the renal and hepatobiliary systems and the blood level of a representative MOMIA was very low, thereby reducing background noise caused by circulating molecular probes. These findings demonstrate the feasibility of preparing single molecules with the capacity to emit discernible and diagnostic fluorescent and gamma-radiations for optical and nuclear imaging of living organisms.

  4. Multimodal Detection of Depression in Clinical Interviews

    PubMed Central

    Dibeklioğlu, Hamdi; Hammal, Zakia; Yang, Ying; Cohn, Jeffrey F.

    2016-01-01

    Current methods for depression assessment depend almost entirely on clinical interview or self-report ratings. Such measures lack systematic and efficient ways of incorporating behavioral observations that are strong indicators of psychological disorder. We compared a clinical interview of depression severity with automatic measurement in 48 participants undergoing treatment for depression. Interviews were obtained at 7-week intervals on up to four occasions. Following standard cut-offs, participants at each session were classified as remitted, intermediate, or depressed. Logistic regression classifiers using leave-one-out validation were compared for facial movement dynamics, head movement dynamics, and vocal prosody individually and in combination. Accuracy (remitted versus depressed) for facial movement dynamics was higher than that for head movement dynamics; and each was substantially higher than that for vocal prosody. Accuracy for all three modalities together reached 88.93%, exceeding that for any single modality or pair of modalities. These findings suggest that automatic detection of depression from behavioral indicators is feasible and that multimodal measures afford most powerful detection. PMID:27213186

  5. Recent Advances in Higher-Order, Multimodal, Biomedical Imaging Agents.

    PubMed

    Rieffel, James; Chitgupi, Upendra; Lovell, Jonathan F

    2015-09-16

    Advances in biomedical imaging have spurred the development of integrated multimodal scanners, usually capable of two simultaneous imaging modes. The long-term vision of higher-order multimodality is to improve diagnostics or guidance through the analysis of complementary, data-rich, co-registered images. Synergies achieved through combined modalities could enable researchers to better track diverse physiological and structural events, analyze biodistribution and treatment efficacy, and compare established and emerging modalities. Higher-order multimodal approaches stand to benefit from molecular imaging probes and, in recent years, contrast agents that have hypermodal characteristics have increasingly been reported in preclinical studies. Given the chemical requirements for contrast agents representing various modalities to be integrated into a single entity, the higher-order multimodal agents reported so far tend to be of nanoparticulate form. To date, the majority of reported nanoparticles have included components that are active for magnetic resonance. Herein, recent progress in higher-order multimodal imaging agents is reviewed, spanning a range of material and structural classes, and demonstrating utility in three (or more) imaging modalities.

  6. The dynamics of multimodal integration: The averaging diffusion model.

    PubMed

    Turner, Brandon M; Gao, Juan; Koenig, Scott; Palfy, Dylan; L McClelland, James

    2017-03-08

    We combine extant theories of evidence accumulation and multi-modal integration to develop an integrated framework for modeling multimodal integration as a process that unfolds in real time. Many studies have formulated sensory processing as a dynamic process where noisy samples of evidence are accumulated until a decision is made. However, these studies are often limited to a single sensory modality. Studies of multimodal stimulus integration have focused on how best to combine different sources of information to elicit a judgment. These studies are often limited to a single time point, typically after the integration process has occurred. We address these limitations by combining the two approaches. Experimentally, we present data that allow us to study the time course of evidence accumulation within each of the visual and auditory domains as well as in a bimodal condition. Theoretically, we develop a new Averaging Diffusion Model in which the decision variable is the mean rather than the sum of evidence samples and use it as a base for comparing three alternative models of multimodal integration, allowing us to assess the optimality of this integration. The outcome reveals rich individual differences in multimodal integration: while some subjects' data are consistent with adaptive optimal integration, reweighting sources of evidence as their relative reliability changes during evidence integration, others exhibit patterns inconsistent with optimality.

  7. User expertise in speech centered multimodal human computer interaction

    NASA Astrophysics Data System (ADS)

    Chandrasekaran, Rajesh; Dusan, Sorin; Flanagan, James L.

    2004-10-01

    Multimodal interfaces aim to permit natural communication by speech and gesture. Typically the speech modality bears the principal information in the interaction with gesture complementing spoken commands. A continuing challenge is how to correlate and interpret the simultaneous inputs to estimate meaning and user intent. User expertise and familiarity figure prominently in the interpretation. The present research studies the effect of user expertise on multimodal human computer interaction. Users are classified into experienced and inexperienced depending on the amount of their exposure and interaction with multimodal systems. Each user is asked to perform simple tasks using a multimodal system. For each task the automatically recognized speech input is time stamped and the lag or lead of the gesture input is computed with respect to this time stamp. The time interval around the time stamp in which all the users' gesture inputs occur is determined. For experienced users this interval averages 56.9% less than that for inexperienced users. The implication is that for experienced users the spoken input are the corresponding gesture input are more closely related in time than for inexperienced users. This behavior can be exploited in multimodal systems to increase efficiency and reduce time of response for the system.

  8. High-contrast qubit interactions using multimode cavity QED.

    PubMed

    McKay, David C; Naik, Ravi; Reinhold, Philip; Bishop, Lev S; Schuster, David I

    2015-02-27

    We introduce a new multimode cavity QED architecture for superconducting circuits that can be used to implement photonic memories, more efficient Purcell filters, and quantum simulations of photonic materials. We show that qubit interactions mediated by multimode cavities can have exponentially improved contrast for two qubit gates without sacrificing gate speed. Using two qubits coupled via a three-mode cavity system we spectroscopically observe multimode strong couplings up to 102 MHz and demonstrate suppressed interactions off resonance of 10 kHz when the qubits are ≈600  MHz detuned from the cavity resonance. We study Landau-Zener transitions in our multimode systems and demonstrate quasiadiabatic loading of single photons into the multimode cavity in 25 ns. We introduce an adiabatic gate protocol to realize a controlled-Z gate between the qubits in 95 ns and create a Bell state with 94.7% fidelity. This corresponds to an on/off ratio (gate contrast) of 1000.

  9. [Multimodal pain therapy - implementation of process management - an attempt to consider management approaches].

    PubMed

    Dunkel, Marion; Kramp, Melanie

    2012-07-01

    The combination of medical and economical proceedings allows new perspectives in the illustration of medical workflows. Considering structural and developmental aspects multimodal therapy programs show similarities with typical subjects of economic process systems. By pointing out the strategic appearance of the multimodal pain therapy concept multimodal approaches can be described to some extent by using management approaches. E. g., an economic process landscape can be used to represent procedures of a multimodal pain therapy program. © Georg Thieme Verlag Stuttgart · New York.

  10. Multimodal Representations of Identity in the English-as-an-Additional-Language Classroom in South Africa

    ERIC Educational Resources Information Center

    Kajee, Leila

    2011-01-01

    This paper explores the multimodal engagement of English-as-an-additional-language (EAL) students in a classroom in Johannesburg. Within a social semiotic framework, and using constructions of design and identity to understand the students' multimodal engagement, the paper argues that multimodal representations offer EAL students from…

  11. New Technologies, New Possibilities for the Arts and Multimodality in English Language Arts

    ERIC Educational Resources Information Center

    Williams, Wendy R.

    2014-01-01

    This article discusses the arts, multimodality, and new technologies in English language arts. It then turns to the example of the illuminated text--a multimodal book report consisting of animated text, music, and images--to consider how art, multimodality, and technology can work together to support students' reading of literature and inspire…

  12. Multimodality, Ethnodrama, and the Preparation of Pre-Service Teachers of Writing

    ERIC Educational Resources Information Center

    Hobson, Sarah

    2014-01-01

    Given the prevalence of multimodal texts in today's world, it is not surprising that adolescent literacies are as dynamic, multimodal and visual as the texts with which they interact. As Kress & Van Leeuwen (1996) have outlined, the multimodal texts that make up a large percentage of our world consist of a range of modes (auditory,…

  13. New Technologies, New Possibilities for the Arts and Multimodality in English Language Arts

    ERIC Educational Resources Information Center

    Williams, Wendy R.

    2014-01-01

    This article discusses the arts, multimodality, and new technologies in English language arts. It then turns to the example of the illuminated text--a multimodal book report consisting of animated text, music, and images--to consider how art, multimodality, and technology can work together to support students' reading of literature and inspire…

  14. The Work of Comics Collaborations: Considerations of Multimodal Composition for Writing Scholarship and Pedagogy

    ERIC Educational Resources Information Center

    Scanlon, Molly J.

    2015-01-01

    Though multimodality is increasingly incorporated into our pedagogies and scholarship, explorations of collaborative multimodal composition are lacking. Existing literature on collaborative writing focuses predominately on texts either composed in singular modes or by a single author, neglecting the ways in which multimodal texts are composed…

  15. The Work of Comics Collaborations: Considerations of Multimodal Composition for Writing Scholarship and Pedagogy

    ERIC Educational Resources Information Center

    Scanlon, Molly J.

    2015-01-01

    Though multimodality is increasingly incorporated into our pedagogies and scholarship, explorations of collaborative multimodal composition are lacking. Existing literature on collaborative writing focuses predominately on texts either composed in singular modes or by a single author, neglecting the ways in which multimodal texts are composed…

  16. MULTIMODAL IMAGING IN VORTEX VEIN VARICES.

    PubMed

    Veronese, Chiara; Staurenghi, Giovanni; Pellegrini, Marco; Maiolo, Chiara; Primavera, Laura; Morara, Mariachiara; Armstrong, Grayson W; Ciardella, Antonio P

    2017-03-22

    The aim of this study is to describe the clinical presentation of vortex vein varices with multimodal imaging. The authors carried out a retrospective case series of eight patients (7 female, 1 male) with an average age of 60.2 years (min 8, max 84, median 68.5) presenting with vortex vein varices. All patients were evaluated at the Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy and at Luigi Sacco Hospital, University of Milan, Milan, Italy. Patients underwent complete ophthalmologic examinations, including best corrected visual acuity, intraocular pressure, anterior segment, and fundus examination. Imaging studies, including fundus color photography, near-infrared reflectance imaging, fundus autofluorescence, fluorescein angiography, indocyanine green angiography, and spectral-domain enhanced depth imaging optical coherence tomography were also performed. Ultra-widefield fluorescein angiography and ultra-widefield indocyanine angiography using the Heidelberg Retina Angiograph and the Staurenghi 230 SLO Retina Lens were used to demonstrate the disappearance of all retinal lesions when pressure was applied to the globe. All eight cases initially presented to the emergency room. One patient presented secondary to trauma, two patients presented for suspected hemangioma, whereas the other five were referred to the authors' hospitals for suspected retinal lesions. On examination, retinal abnormalities were identified in all 8 patients, with 7 (87.5%) oculus dexter and 1 (12.5%) oculus sinister, and with 1 (12.5%) inferotemporally, 3 (37.5%) superonasally, 3 (37.5%) inferonasally, and 1 (12.5%) inferiorly. Fundus color photography showed an elevated lesion in seven patients and a nonelevated red lesion in one patient. In all patients, near-infrared reflectance imaging showed a hyporeflective lesion in the periphery of the retina. Fundus autofluorescence identified round hypofluorescent rings surrounding weakly hyperfluorescent lesions in all

  17. Multimodal intrathecal analgesia in refractory cancer pain.

    PubMed

    Mastenbroek, Thierry C; Kramp-Hendriks, Bianca J; Kallewaard, Jan Willem; Vonk, Johanna M

    2017-01-01

    Cancer pain treatment has improved over the last decades. The majority of this population can be treated effectively with analgesics following the Guidelines of the original World Health Organisation (WHO). Unfortunately 10-15% of these patients still suffer from severe and refractory cancer pain, especially in the terminal phases of disease and require additional pain management modalities. Therefore, end-stage clinical interventions are particularly needed to minimize the perception of pain. With intrathecal therapy (ITT), drugs are delivered close to their site of action in the central nervous system avoiding first-pass metabolism and blood-brain barrier. It may improve analgesia with a smaller dose and possibly achieve a reduction in systemic or cerebral side effects compared to oral supplied medication alone. Multimodal analgesia enables further dose reduction with improved analgesia and fewer side effects. In this retrospective research we investigated the effectiveness and side-effect profile of intrathecal morphine, bupivacaine and clonidine. Patients were followed until death occurred. Pain scores and side effects were recorded before initiating ITT (T0), just after initiating ITT (T1), at hospital discharge (T2), in the ambulant setting (T3) and the last obtained scores before death occurred (T4). Nine patients were included who suffered from severe and refractory cancer pain, not reacting to conventional pain management or had intolerable side effects. Primary tumour location was pancreatic (4), urothelial (3) and prostate (2). Primary pain was considered neuropathic or mixed neuropathic-nociceptive. The treatment team consisted of an anaesthetist, specialized nurse in coordination with primary physician, treating oncologist and specialized home care. All patients were free of pain after initiation of the intrathecal therapy. The average follow-up period was 11 weeks in which there was a slight increase in NRS-score. In the last days before death

  18. Multimodal Sensory Distortions in Postpartum Exacerbation of Schizophrenia.

    PubMed

    Mehta, Urvakhsh Meherwan; Naveen Kumar, C; Venkatasubramanian, Ganesan; Thirthalli, Jagadisha

    Sensory distortions of body image commonly occur during migraine, seizures, nondominant cortical infarcts and hallucinogen abuse. We report the case of a 30-year-old woman with paranoid schizophrenia presenting with postpartum onset multimodal sensory distortions in the absence of any neurological disorders or substance use. Her symptoms involved persistent facial/body metamorphopsia (distorted images) and vocal paracousis (distorted voices), in the absence of visual hallucinations, illusions or agnosia. Neuropsychological assessments revealed deficits on visual processing tasks. Neuroimaging, electroencephalography and ophthalmological evaluation revealed no abnormalities. The multimodal sensory distortions responded to antipsychotic treatment, paralleling improvement in other schizophrenia psychopathology, over a period of one month. Prominent and persistent multimodal sensory distortions like metamorphopsia and paracousis in the presence of psychotic symptoms warrant a detailed neurological and general medical work-up. These symptoms presenting in the absence of neurological or substance use disorders may be a component of schizophrenia.

  19. A Multimodal User Authentication System Using Faces and Gestures

    PubMed Central

    Choi, Hyunsoek; Park, Hyeyoung

    2015-01-01

    As a novel approach to perform user authentication, we propose a multimodal biometric system that uses faces and gestures obtained from a single vision sensor. Unlike typical multimodal biometric systems using physical information, the proposed system utilizes gesture video signals combined with facial images. Whereas physical information such as face, fingerprints, and iris is fixed and not changeable, behavioral information such as gestures and signatures can be freely changed by the user, similar to a password. Therefore, it can be a countermeasure when the physical information is exposed. We aim to investigate the potential possibility of using gestures as a signal for biometric system and the robustness of the proposed multimodal user authentication system. Through computational experiments on a public database, we confirm that gesture information can help to improve the authentication performance. PMID:26247018

  20. Quantitative multimodality imaging in cancer research and therapy.

    PubMed

    Yankeelov, Thomas E; Abramson, Richard G; Quarles, C Chad

    2014-11-01

    Advances in hardware and software have enabled the realization of clinically feasible, quantitative multimodality imaging of tissue pathophysiology. Earlier efforts relating to multimodality imaging of cancer have focused on the integration of anatomical and functional characteristics, such as PET-CT and single-photon emission CT (SPECT-CT), whereas more-recent advances and applications have involved the integration of multiple quantitative, functional measurements (for example, multiple PET tracers, varied MRI contrast mechanisms, and PET-MRI), thereby providing a more-comprehensive characterization of the tumour phenotype. The enormous amount of complementary quantitative data generated by such studies is beginning to offer unique insights into opportunities to optimize care for individual patients. Although important technical optimization and improved biological interpretation of multimodality imaging findings are needed, this approach can already be applied informatively in clinical trials of cancer therapeutics using existing tools. These concepts are discussed herein.

  1. Object recognition through a multi-mode fiber

    NASA Astrophysics Data System (ADS)

    Takagi, Ryosuke; Horisaki, Ryoichi; Tanida, Jun

    2017-04-01

    We present a method of recognizing an object through a multi-mode fiber. A number of speckle patterns transmitted through a multi-mode fiber are provided to a classifier based on machine learning. We experimentally demonstrated binary classification of face and non-face targets based on the method. The measurement process of the experimental setup was random and nonlinear because a multi-mode fiber is a typical strongly scattering medium and any reference light was not used in our setup. Comparisons between three supervised learning methods, support vector machine, adaptive boosting, and neural network, are also provided. All of those learning methods achieved high accuracy rates at about 90% for the classification. The approach presented here can realize a compact and smart optical sensor. It is practically useful for medical applications, such as endoscopy. Also our study indicated a promising utilization of artificial intelligence, which has rapidly progressed, for reducing optical and computational costs in optical sensing systems.

  2. Multimode model for projective photon-counting measurements

    SciTech Connect

    Tualle-Brouri, Rosa; Ourjoumtsev, Alexei; Dantan, Aurelien; Grangier, Philippe; Wubs, Martijn; Soerensen, Anders S.

    2009-07-15

    We present a general model to account for the multimode nature of the quantum electromagnetic field in projective photon-counting measurements. We focus on photon-subtraction experiments, where non-Gaussian states are produced conditionally. These are useful states for continuous-variable quantum-information processing. We present a general method called mode reduction that reduces the multimode model to an effective two-mode problem. We apply this method to a multimode model describing broadband parametric down-conversion, thereby improving the analysis of existing experimental results. The main improvement is that spatial and frequency filters before the photon detector are taken into account explicitly. We find excellent agreement with previously published experimental results, using fewer free parameters than before, and discuss the implications of our analysis for the optimized production of states with negative Wigner functions.

  3. Content-based TV sports video retrieval using multimodal analysis

    NASA Astrophysics Data System (ADS)

    Yu, Yiqing; Liu, Huayong; Wang, Hongbin; Zhou, Dongru

    2003-09-01

    In this paper, we propose content-based video retrieval, which is a kind of retrieval by its semantical contents. Because video data is composed of multimodal information streams such as video, auditory and textual streams, we describe a strategy of using multimodal analysis for automatic parsing sports video. The paper first defines the basic structure of sports video database system, and then introduces a new approach that integrates visual stream analysis, speech recognition, speech signal processing and text extraction to realize video retrieval. The experimental results for TV sports video of football games indicate that the multimodal analysis is effective for video retrieval by quickly browsing tree-like video clips or inputting keywords within predefined domain.

  4. Joint sparse representation for robust multimodal biometrics recognition.

    PubMed

    Shekhar, Sumit; Patel, Vishal M; Nasrabadi, Nasser M; Chellappa, Rama

    2014-01-01

    Traditional biometric recognition systems rely on a single biometric signature for authentication. While the advantage of using multiple sources of information for establishing the identity has been widely recognized, computational models for multimodal biometrics recognition have only recently received attention. We propose a multimodal sparse representation method, which represents the test data by a sparse linear combination of training data, while constraining the observations from different modalities of the test subject to share their sparse representations. Thus, we simultaneously take into account correlations as well as coupling information among biometric modalities. A multimodal quality measure is also proposed to weigh each modality as it gets fused. Furthermore, we also kernelize the algorithm to handle nonlinearity in data. The optimization problem is solved using an efficient alternative direction method. Various experiments show that the proposed method compares favorably with competing fusion-based methods.

  5. Multimodality Image Fusion-Guided Procedures: Technique, Accuracy, and Applications

    SciTech Connect

    Abi-Jaoudeh, Nadine; Kruecker, Jochen; Kadoury, Samuel; Kobeiter, Hicham; Venkatesan, Aradhana M. Levy, Elliot Wood, Bradford J.

    2012-10-15

    Personalized therapies play an increasingly critical role in cancer care: Image guidance with multimodality image fusion facilitates the targeting of specific tissue for tissue characterization and plays a role in drug discovery and optimization of tailored therapies. Positron-emission tomography (PET), magnetic resonance imaging (MRI), and contrast-enhanced computed tomography (CT) may offer additional information not otherwise available to the operator during minimally invasive image-guided procedures, such as biopsy and ablation. With use of multimodality image fusion for image-guided interventions, navigation with advanced modalities does not require the physical presence of the PET, MRI, or CT imaging system. Several commercially available methods of image-fusion and device navigation are reviewed along with an explanation of common tracking hardware and software. An overview of current clinical applications for multimodality navigation is provided.

  6. Multimode guidance project low frequency ECM simulator: Hardware description

    NASA Astrophysics Data System (ADS)

    Kaye, H. M.

    1982-10-01

    The Multimode Guidance(MMG) Project, part of the Army/Navy Area Defense SAM Technology Prototyping Program, was established to conduct a feasibility demonstration of multimode guidance concepts. Prototype guidance units for advanced, long range missiles are being built and tested under MMG Project sponsorship. The Johns Hopkins University Applied Physics Laboratory has been designated as Government Agent for countermeasures for this project. In support of this effort, a family of computer-controlled ECM simulators is being developed for validation of contractor's multimode guidance prototype designs. The design of the Low Frequency ECM Simulator is documented in two volumes. This report, Volume A, describes the hardware design of the simulator; Volume B describes the software design. This computer-controlled simulator can simulate up to six surveillance frequency jammers in B through F bands and will be used to evaluate the performance of home-on-jamming guidance modes in multiple jammer environments.

  7. Multimodal imaging in a case of deferoxamine induced maculopathy

    PubMed Central

    Gelman, Rony; Kiss, Szilard; Tsang, Stephen H.

    2014-01-01

    Purpose To report a case of deferoxomine induced maculopathy and present the use of multimodal retinal imaging to study this disease entity. Methods Observational case report of one patient. Multimodal imaging with fundus autofluorescence (FAF), infrared imaging (IR), and spectral-domain optical coherence tomography (SD-OCT) was used to investigate the macular changes induced by deferoxamine toxicity. Results A 53 year-old male with a history of beta-thalassemia presented with decreased vision in both eyes one month after initiating deferoxamine therapy. IR imaging showed areas of increased stippled infrared intensity through the macula. FAF revealed diffuse areas of stippled hyperautofluorescence and hypoautofluorescence. SD-OCT changes included disruption of the ellipsoid zone, attenuation of the photoreceptors, and deposits within the retinal pigment epithelium. Conclusions We describe a case of deferoxomine induced maculopathy and present the use of multimodal retinal imaging to study this disease entity. PMID:25372534

  8. Students' Multimodal Construction of the Work-Energy Concept

    NASA Astrophysics Data System (ADS)

    Tang, Kok-Sing; Chee Tan, Seng; Yeo, Jennifer

    2011-09-01

    This article examines the role of multimodalities in representing the concept of work-energy by studying the collaborative discourse of a group of ninth-grade physics students engaging in an inquiry-based instruction. Theorising a scientific concept as a network of meaning relationships across semiotic modalities situated in human activity, this article analyses the students' interactions through their use of natural language, mathematical symbolism, depiction, and gestures, and examines the intertextual meanings made through the integration of these modalities. Results indicate that the thematic integration of multimodalities is both difficult and necessary for students in order to construct a scientific understanding that is congruent with the physics curriculum. More significantly, the difficulties in multimodal integration stem from the subtle differences in the categorical, quantitative, and spatial meanings of the work-energy concept whose contrasts are often not made explicit to the students. The implications of these analyses and findings for science teaching and educational research are discussed.

  9. A Multi-Sample Standoff Multimodal Biometric System

    SciTech Connect

    Barstow, Del R; Patlolla, Dilip Reddy; Mann, Christopher J; Boehnen, Chris Bensing

    2012-01-01

    Abstract The data captured by existing standoff biometric systems typically has lower biometric recognition performance than their close range counterparts due to imaging challenges, pose challenges, and other factors. To assist in overcoming these limitations systems typically perform in a multi-modal capacity such as Honeywell s Combined Face and Iris (CFAIRS) [21] system. While this improves the systems performance, standoff systems have yet to be proven as accurate as their close range equivalents. We will present a standoff system capable of operating up to 7 meters in range. Unlike many systems such as the CFAIRS our system captures high quality 12 MP video allowing for a multi-sample as well as multi-modal comparison. We found that for standoff systems multi-sample improved performance more than multi-modal. For a small test group of 50 subjects we were able to achieve 100% rank one recognition performance with our system.

  10. Multifunctional nanostructured materials for multimodal cancer imaging and therapy.

    PubMed

    Liao, Jinfeng; Qi, Tingting; Chu, Bingyang; Peng, Jinrong; Luo, Feng; Qian, Zhiyong

    2014-01-01

    This paper reviews the recent research and development of multifunctional nanostructured materials for multimodal imaging and therapy. The biomedical applications for multifunctional imaging, diagnosis and therapy are discussed for several nanostructured materials such as polymeric nanoparticles, magnetic nanoparticles, gold nanomaterials, carbon materials, quantum dots and silica nanoparticles. Due to the unique features of nanostructured materials including the large surface area, structural diversity, multifunctionality, and long circulation time in blood, these materials have emerged as attractive preferences for optimized therapy. Multimodal imaging can be introduced to nanostructured materials for precise and fast diagnosis of cancer, which overcomes the shortcoming of single-imaging modality. Meanwhile, nanostructured materials can be also used to deliver therapeutic agents to the disease site in order to accomplish multimodal imaging and simultaneous diagnosis and therapy.

  11. Object recognition through a multi-mode fiber

    NASA Astrophysics Data System (ADS)

    Takagi, Ryosuke; Horisaki, Ryoichi; Tanida, Jun

    2017-02-01

    We present a method of recognizing an object through a multi-mode fiber. A number of speckle patterns transmitted through a multi-mode fiber are provided to a classifier based on machine learning. We experimentally demonstrated binary classification of face and non-face targets based on the method. The measurement process of the experimental setup was random and nonlinear because a multi-mode fiber is a typical strongly scattering medium and any reference light was not used in our setup. Comparisons between three supervised learning methods, support vector machine, adaptive boosting, and neural network, are also provided. All of those learning methods achieved high accuracy rates at about 90% for the classification. The approach presented here can realize a compact and smart optical sensor. It is practically useful for medical applications, such as endoscopy. Also our study indicated a promising utilization of artificial intelligence, which has rapidly progressed, for reducing optical and computational costs in optical sensing systems.

  12. Modelling multimodal expression of emotion in a virtual agent

    PubMed Central

    Pelachaud, Catherine

    2009-01-01

    Over the past few years we have been developing an expressive embodied conversational agent system. In particular, we have developed a model of multimodal behaviours that includes dynamism and complex facial expressions. The first feature refers to the qualitative execution of behaviours. Our model is based on perceptual studies and encompasses several parameters that modulate multimodal behaviours. The second feature, the model of complex expressions, follows a componential approach where a new expression is obtained by combining facial areas of other expressions. Lately we have been working on adding temporal dynamism to expressions. So far they have been designed statically, typically at their apex. Only full-blown expressions could be modelled. To overcome this limitation, we have defined a representation scheme that describes the temporal evolution of the expression of an emotion. It is no longer represented by a static definition but by a temporally ordered sequence of multimodal signals. PMID:19884148

  13. Effect of multimode entanglement on lossy optical quantum metrology

    NASA Astrophysics Data System (ADS)

    Knott, P. A.; Proctor, T. J.; Nemoto, Kae; Dunningham, J. A.; Munro, W. J.

    2014-09-01

    In optical interferometry multimode entanglement is often assumed to be the driving force behind quantum enhanced measurements. Recent work has shown this assumption to be false: single-mode quantum states perform just as well as their multimode entangled counterparts. We go beyond this to show that when photon losses occur, an inevitability in any realistic system, multimode entanglement is actually detrimental to obtaining quantum enhanced measurements. We specifically apply this idea to a superposition of coherent states, demonstrating that these states show a robustness to loss that allows them to significantly outperform their competitors in realistic systems. A practically viable measurement scheme is then presented that allows measurements close to the theoretical bound, even with loss. These results promote an alternate way of approaching optical quantum metrology using single-mode states that we expect to have great implications for the future.

  14. Novel technique for mode selection in a multimode fiber laser.

    PubMed

    Daniel, J M O; Chan, J S P; Kim, J W; Sahu, J K; Ibsen, M; Clarkson, W A

    2011-06-20

    A simple technique for transverse mode selection in a large-mode-area (multimode) fiber laser is described. The technique exploits the different spectral responses of feedback elements based on a fiber Bragg grating and a volume Bragg grating to achieve wavelength-dependent mode filtering. This approach has been applied to a cladding-pumped thulium-doped fiber laser with a multimode core to achieve a single-spatial-mode output beam with a beam propagation factor (M2) of 1.05 at 1923 nm. Without mode selection the free-running fiber laser has a multimode output beam with an M2 parameter of 3.3. Selective excitation of higher order modes is also possible via the technique and preliminary results for laser oscillation on the LP11 mode are also discussed along with the prospects for scaling to higher power levels.

  15. "Multimodal Contrast" from the Multivariate Analysis of Hyperspectral CARS Images

    NASA Astrophysics Data System (ADS)

    Tabarangao, Joel T.

    The typical contrast mechanism employed in multimodal CARS microscopy involves the use of other nonlinear imaging modalities such as two-photon excitation fluorescence (TPEF) microscopy and second harmonic generation (SHG) microscopy to produce a molecule-specific pseudocolor image. In this work, I explore the use of unsupervised multivariate statistical analysis tools such as Principal Component Analysis (PCA) and Vertex Component Analysis (VCA) to provide better contrast using the hyperspectral CARS data alone. Using simulated CARS images, I investigate the effects of the quadratic dependence of CARS signal on concentration on the pixel clustering and classification and I find that a normalization step is necessary to improve pixel color assignment. Using an atherosclerotic rabbit aorta test image, I show that the VCA algorithm provides pseudocolor contrast that is comparable to multimodal imaging, thus showing that much of the information gleaned from a multimodal approach can be sufficiently extracted from the CARS hyperspectral stack itself.

  16. [Multimodal medical image registration using cubic spline interpolation method].

    PubMed

    He, Yuanlie; Tian, Lianfang; Chen, Ping; Wang, Lifei; Ye, Guangchun; Mao, Zongyuan

    2007-12-01

    Based on the characteristic of the PET-CT multimodal image series, a novel image registration and fusion method is proposed, in which the cubic spline interpolation method is applied to realize the interpolation of PET-CT image series, then registration is carried out by using mutual information algorithm and finally the improved principal component analysis method is used for the fusion of PET-CT multimodal images to enhance the visual effect of PET image, thus satisfied registration and fusion results are obtained. The cubic spline interpolation method is used for reconstruction to restore the missed information between image slices, which can compensate for the shortage of previous registration methods, improve the accuracy of the registration, and make the fused multimodal images more similar to the real image. Finally, the cubic spline interpolation method has been successfully applied in developing 3D-CRT (3D Conformal Radiation Therapy) system.

  17. Quantitative multimodality imaging in cancer research and therapy

    PubMed Central

    Yankeelov, Thomas E.; Abramson, Richard G.; Quarles, C. Chad

    2016-01-01

    Advances in hardware and software have enabled the realization of clinically feasible, quantitative multimodality imaging of tissue pathophysiology. Earlier efforts relating to multimodality imaging of cancer have focused on the integration of anatomical and functional characteristics, such as PET–CT and single-photon emission CT (SPECT–CT), whereas more-recent advances and applications have involved the integration of multiple quantitative, functional measurements (for example, multiple PET tracers, varied MRI contrast mechanisms, and PET–MRI), thereby providing a more-comprehensive characterization of the tumour phenotype. The enormous amount of complementary quantitative data generated by such studies is beginning to offer unique insights into opportunities to optimize care for individual patients. Although important technical optimization and improved biological interpretation of multimodality imaging findings are needed, this approach can already be applied informatively in clinical trials of cancer therapeutics using existing tools. These concepts are discussed herein. PMID:25113842

  18. Multimodal evaluation of the amygdala's functional connectivity.

    PubMed

    Kerestes, Rebecca; Chase, Henry W; Phillips, Mary L; Ladouceur, Cecile D; Eickhoff, Simon B

    2017-01-09

    The amygdala is one of the most extensively studied human brain regions and undisputedly plays a central role in many psychiatric disorders. However, an outstanding question is whether connectivity of amygdala subregions, specifically the centromedial (CM), laterobasal (LB) and superficial (SF) nuclei, are modulated by brain state (i.e., task vs. rest). Here, using a multimodal approach, we directly compared meta-analytic connectivity modeling (MACM) and specific co-activation likelihood estimation (SCALE)-derived estimates of CM, LB and SF task-based co-activation to the functional connectivity of these nuclei as assessed by resting state fmri (rs-fmri). Finally, using a preexisting resting state functional connectivity-derived cortical parcellation, we examined both MACM and rs-fmri amygdala subregion connectivity with 17 large-scale networks, to explicitly address how the amygdala interacts with other large-scale neural networks. Analyses revealed strong differentiation of CM, LB and SF connectivity patterns with other brain regions, both in task-dependent and task-independent contexts. All three regions, however, showed convergent connectivity with the right ventrolateral prefrontal cortex (VLPFC) that was not driven by high base rate levels of activation. Similar patterns of connectivity across rs-fmri and MACM were observed for each subregion, suggesting a similar network architecture of amygdala connectivity with the rest of the brain across tasks and resting state for each subregion, that may be modified in the context of specific task demands. These findings support animal models that posit a parallel model of amygdala functioning, but importantly, also modify this position to suggest integrative processing in the amygdala.

  19. Driver drowsiness detection using multimodal sensor fusion

    NASA Astrophysics Data System (ADS)

    Andreeva, Elena O.; Aarabi, Parham; Philiastides, Marios G.; Mohajer, Keyvan; Emami, Majid

    2004-04-01

    This paper proposes a multi-modal sensor fusion algorithm for the estimation of driver drowsiness. Driver sleepiness is believed to be responsible for more than 30% of passenger car accidents and for 4% of all accident fatalities. In commercial vehicles, drowsiness is blamed for 58% of single truck accidents and 31% of commercial truck driver fatalities. This work proposes an innovative automatic sleep-onset detection system. Using multiple sensors, the driver"s body is studied as a mechanical structure of springs and dampeners. The sleep-detection system consists of highly sensitive triple-axial accelerometers to monitor the driver"s upper body in 3-D. The subject is modeled as a linear time-variant (LTV) system. An LMS adaptive filter estimation algorithm generates the transfer function (i.e. weight coefficients) for this LTV system. Separate coefficients are generated for the awake and asleep states of the subject. These coefficients are then used to train a neural network. Once trained, the neural network classifies the condition of the driver as either awake or asleep. The system has been tested on a total of 8 subjects. The tests were conducted on sleep-deprived individuals for the sleep state and on fully awake individuals for the awake state. When trained and tested on the same subject, the system detected sleep and awake states of the driver with a success rate of 95%. When the system was trained on three subjects and then retested on a fourth "unseen" subject, the classification rate dropped to 90%. Furthermore, it was attempted to correlate driver posture and sleepiness by observing how car vibrations propagate through a person"s body. Eight additional subjects were studied for this purpose. The results obtained in this experiment proved inconclusive which was attributed to significant differences in the individual habitual postures.

  20. Quantitative multimodal multiparametric imaging in Alzheimer's disease.

    PubMed

    Zhao, Qian; Chen, Xueqi; Zhou, Yun

    2016-03-01

    Alzheimer's disease (AD) is a progressive neurodegenerative disorder, causing changes in memory, thinking, and other dysfunction of brain functions. More and more people are suffering from the disease. Early neuroimaging techniques of AD are needed to develop. This review provides a preliminary summary of the various neuroimaging techniques that have been explored for in vivo imaging of AD. Recent advances in magnetic resonance (MR) techniques, such as functional MR imaging (fMRI) and diffusion MRI, give opportunities to display not only anatomy and atrophy of the medial temporal lobe, but also at microstructural alterations or perfusion disturbance within the AD lesions. Positron emission tomography (PET) imaging has become the subject of intense research for the diagnosis and facilitation of drug development of AD in both animal models and human trials due to its non-invasive and translational characteristic. Fluorodeoxyglucose (FDG) PET and amyloid PET are applied in clinics and research departments. Amyloid beta (Aβ) imaging using PET has been recognized as one of the most important methods for the early diagnosis of AD, and numerous candidate compounds have been tested for Aβ imaging. Besides in vivo imaging method, a lot of ex vivo modalities are being used in the AD researches. Multiphoton laser scanning microscopy, neuroimaging of metals, and several metal bioimaging methods are also mentioned here. More and more multimodality and multiparametric neuroimaging techniques should improve our understanding of brain function and open new insights into the pathophysiology of AD. We expect exciting results will emerge from new neuroimaging applications that will provide scientific and medical benefits.

  1. Multimodality Local Therapy for Retroperitoneal Sarcoma

    SciTech Connect

    Paryani, Nitesh N.; Zlotecki, Robert A.; Swanson, Erika L.; Morris, Christopher G.; Grobmyer, Stephen R.; Hochwald, Steven N.; Marcus, Robert B.; Indelicato, Daniel J.

    2012-03-01

    Purpose: Soft-tissue sarcomas of the retroperitoneum are rare tumors comprising less than 1% of all malignancies. Although surgery continues as the mainstay of treatment, the large size of these tumors coupled with their proximity to critical structures make resection with wide margins difficult to achieve. The role and timing of radiotherapy are controversial. This study updates our institutional experience using multimodality local therapy for resectable retroperitoneal sarcoma and identifies prognostic factors impacting disease control and survival. Methods and Materials: Between 1974 and 2007, 58 patients with nonmetastatic retroperitoneal sarcoma were treated with surgery and radiation at University of Florida. The median age at radiotherapy was 57 years old (range, 18-80 years). Forty-two patients received preoperative radiotherapy and 16 received postoperative radiotherapy. Nineteen patients received 1.8 Gy once daily and 39 patients received 1.2 Gy twice daily. Variables analyzed for prognostic value included age, grade, kidney involvement, histology, de novo versus recurrent presentation, tumor diameter, margin status, radiotherapy sequencing (preoperative vs. postoperative), total radiation dose, fractionation scheme, and treatment era. Results: The 5-year overall survival, cause-specific survival, and local control rates were 49%, 58%, and 62%, respectively. Nearly two-thirds of disease failures involved a component of local progression. On multivariate analysis, only margin status was significantly associated with improved 5-year local control (85%, negative margins; 63%, microscopic positive margins; 0%, gross positive margins; p < 0.0001) and 5-year overall survival (64%, negative margins; 56%, microscopic positive margins; 13%, gross positive margins; p = 0.0012). Thirty-one Grade 3 or greater toxicities were observed in 22 patients, including two treatment-related deaths (3%). Conclusion: For retroperitoneal sarcoma, local control remains a

  2. Multimodal cues improve prey localization under complex environmental conditions

    PubMed Central

    Rhebergen, F.; Taylor, R. C.; Ryan, M. J.; Page, R. A.; Halfwerk, W.

    2015-01-01

    Predators often eavesdrop on sexual displays of their prey. These displays can provide multimodal cues that aid predators, but the benefits in attending to them should depend on the environmental sensory conditions under which they forage. We assessed whether bats hunting for frogs use multimodal cues to locate their prey and whether their use varies with ambient conditions. We used a robotic set-up mimicking the sexual display of a male túngara frog (Physalaemus pustulosus) to test prey assessment by fringe-lipped bats (Trachops cirrhosus). These predatory bats primarily use sound of the frog's call to find their prey, but the bats also use echolocation cues returning from the frog's dynamically moving vocal sac. In the first experiment, we show that multimodal cues affect attack behaviour: bats made narrower flank attack angles on multimodal trials compared with unimodal trials during which they could only rely on the sound of the frog. In the second experiment, we explored the bat's use of prey cues in an acoustically more complex environment. Túngara frogs often form mixed-species choruses with other frogs, including the hourglass frog (Dendropsophus ebraccatus). Using a multi-speaker set-up, we tested bat approaches and attacks on the robofrog under three different levels of acoustic complexity: no calling D. ebraccatus males, two calling D. ebraccatus males and five D. ebraccatus males. We found that bats are more directional in their approach to the robofrog when more D. ebraccatus males were calling. Thus, bats seemed to benefit more from multimodal cues when confronted with increased levels of acoustic complexity in their foraging environments. Our data have important consequences for our understanding of the evolution of multimodal sexual displays as they reveal how environmental conditions can alter the natural selection pressures acting on them. PMID:26336176

  3. Automatic identification of reticular pseudodrusen using multimodal retinal image analysis.

    PubMed

    van Grinsven, Mark J J P; Buitendijk, Gabriëlle H S; Brussee, Corina; van Ginneken, Bram; Hoyng, Carel B; Theelen, Thomas; Klaver, Caroline C W; Sánchez, Clara I

    2015-01-08

    To examine human performance and agreement on reticular pseudodrusen (RPD) detection and quantification by using single- and multimodality grading protocols and to describe and evaluate a machine learning system for the automatic detection and quantification of reticular pseudodrusen by using single- and multimodality information. Color fundus, fundus autofluoresence, and near-infrared images of 278 eyes from 230 patients with or without presence of RPD were used in this study. All eyes were scored for presence of RPD during single- and multimodality setups by two experienced observers and a developed machine learning system. Furthermore, automatic quantification of RPD area was performed by the proposed system and compared with human delineations. Observers obtained a higher performance and better interobserver agreement for RPD detection with multimodality grading, achieving areas under the receiver operating characteristic (ROC) curve of 0.940 and 0.958, and a κ agreement of 0.911. The proposed automatic system achieved an area under the ROC of 0.941 with a multimodality setup. Automatic RPD quantification resulted in an intraclass correlation (ICC) value of 0.704, which was comparable with ICC values obtained between single-modality manual delineations. Observer performance and agreement for RPD identification improved significantly by using a multimodality grading approach. The developed automatic system showed similar performance as observers, and automatic RPD area quantification was in concordance with manual delineations. The proposed automatic system allows for a fast and accurate identification and quantification of RPD, opening the way for efficient quantitative imaging biomarkers in large data set analysis. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.

  4. Multimodal cues improve prey localization under complex environmental conditions.

    PubMed

    Rhebergen, F; Taylor, R C; Ryan, M J; Page, R A; Halfwerk, W

    2015-09-07

    Predators often eavesdrop on sexual displays of their prey. These displays can provide multimodal cues that aid predators, but the benefits in attending to them should depend on the environmental sensory conditions under which they forage. We assessed whether bats hunting for frogs use multimodal cues to locate their prey and whether their use varies with ambient conditions. We used a robotic set-up mimicking the sexual display of a male túngara frog (Physalaemus pustulosus) to test prey assessment by fringe-lipped bats (Trachops cirrhosus). These predatory bats primarily use sound of the frog's call to find their prey, but the bats also use echolocation cues returning from the frog's dynamically moving vocal sac. In the first experiment, we show that multimodal cues affect attack behaviour: bats made narrower flank attack angles on multimodal trials compared with unimodal trials during which they could only rely on the sound of the frog. In the second experiment, we explored the bat's use of prey cues in an acoustically more complex environment. Túngara frogs often form mixed-species choruses with other frogs, including the hourglass frog (Dendropsophus ebraccatus). Using a multi-speaker set-up, we tested bat approaches and attacks on the robofrog under three different levels of acoustic complexity: no calling D. ebraccatus males, two calling D. ebraccatus males and five D. ebraccatus males. We found that bats are more directional in their approach to the robofrog when more D. ebraccatus males were calling. Thus, bats seemed to benefit more from multimodal cues when confronted with increased levels of acoustic complexity in their foraging environments. Our data have important consequences for our understanding of the evolution of multimodal sexual displays as they reveal how environmental conditions can alter the natural selection pressures acting on them.

  5. Multimode fiber focusing lens based on plasmonic structures

    NASA Astrophysics Data System (ADS)

    Xu, Yihang; Lu, Yongjiao; Zhu, Zheng; Shi, Jinhui; Guan, Chunying; Yuan, Libo

    2016-10-01

    In the present work, a compact all-fiber plasmonic focusing beam generator with single and multiple spots is proposed and demonstrated in a conventional multimode fiber. Here, the focusing beam generator is composed of air slit arrays perforated through the gold films deposited on the end facet of a multimode fiber. The array of nanoscale slits with varying widths is used to modulate phase distribution of the focused light. An all-fiber focusing beam generator provides many advantages, such as self-alignment, high flexibility, lower insert loss, and easy portability, which is of importance to realize optical trapping, micromanipulation, beam shaping, and fiber integrated devices.

  6. Multimodal Analgesia for Acute Postoperative and Trauma-Related Pain.

    PubMed

    Polomano, Rosemary C; Fillman, Mechele; Giordano, Nicholas A; Vallerand, April Hazard; Nicely, Kelly L Wiltse; Jungquist, Carla R

    2017-03-01

    : Multimodal analgesia, which combines analgesic drugs from different classes and employs analgesic techniques that target different mechanisms of pain, is recommended in the treatment of acute postoperative and trauma-related pain because its synergistic effect maximizes pain relief at lower analgesic doses, thereby reducing the risk of adverse drug effects. Using a case-based approach, this article reviews various multimodal analgesic therapies used in the treatment of acute pain; discusses their benefits; and summarizes findings from related research, recommendations from evidence-based practice guidelines, and expert consensus reports.

  7. Vaccine-enhanced artificial immune system for multimodal function optimization.

    PubMed

    Woldemariam, Kumlachew M; Yen, Gary G

    2010-02-01

    This paper emulates a biological notion in vaccines to promote exploration in the search space for solving multimodal function optimization problems using artificial immune systems (AISs). In this method, we first divide the decision space into equal subspaces. The vaccine is then randomly extracted from each subspace. A few of these vaccines, in the form of weakened antigens, are then injected into the algorithm to enhance the exploration of global and local optima. The goal of this process is to lead the antibodies to unexplored areas. Using this biologically motivated notion, we design the vaccine-enhanced AIS for multimodal function optimization, achieving promising performance.

  8. State deadbeat response and observability in multi-modal systems

    NASA Technical Reports Server (NTRS)

    Conner, L. T., Jr.; Stanford, D. P.

    1984-01-01

    Two aspects of multimodal systems are examined. It is shown that any completely controllable system with state dimension n not exceeding three allows a choice of feedback matrices resulting in a state deadbeat response. Some of the results presented here are valid for arbitrary n, and it is suggested that for all n the state deadbeat response can be obtained under the hypothesis of complete controllability. The controllability canonical form for a multimodal system is refined by introducing a notion of observability which is dual to controllability for these systems.

  9. Multimodality imaging assessment for Thoraflex hybrid total arch replacement.

    PubMed

    Wong, Randolph Hl; Ho, Jacky Yk; Underwood, Malcolm J

    2016-06-01

    Conventionally, aortic pathologies involving the ascending, arch, and descending thoracic aorta are treated by a staged operation. The Thoraflex device is a composite 4-branched graft with a distal endovascular stent, which allows one-stage treatment of these pathologies. We describe our multimodality hybrid approach for total arch replacement using the Thoraflex device with the adjunct of intraoperative 3-dimensional transesophageal echocardiography, Endo-EYE endoscopy, and on-table aortography in a hybrid operating room. These multimodality assessments can ascertain adequate sealing of a distal aortic tear and proper opening of the endograft, and provide on-table functional assessment of false lumen hemodynamics. Early results are promising.

  10. Design, Performance and Optimization for Multimodal Radar Operation

    PubMed Central

    Bhat, Surendra S.; Narayanan, Ram M.; Rangaswamy, Muralidhar

    2012-01-01

    This paper describes the underlying methodology behind an adaptive multimodal radar sensor that is capable of progressively optimizing its range resolution depending upon the target scattering features. It consists of a test-bed that enables the generation of linear frequency modulated waveforms of various bandwidths. This paper discusses a theoretical approach to optimizing the bandwidth used by the multimodal radar. It also discusses the various experimental results obtained from measurement. The resolution predicted from theory agrees quite well with that obtained from experiments for different target arrangements.

  11. Multi-modality neuro-monitoring: conventional clinical trial design.

    PubMed

    Georgiadis, Alexandros L; Palesch, Yuko Y; Zygun, David; Hemphill, J Claude; Robertson, Claudia S; Leroux, Peter D; Suarez, Jose I

    2015-06-01

    Multi-modal monitoring has become an integral part of neurointensive care. However, our approach is at this time neither standardized nor backed by data from randomized controlled trials. The goal of the second Neurocritical Care Research Conference was to discuss research priorities in multi-modal monitoring, what research tools are available, as well as the latest advances in clinical trial design. This section of the meeting was focused on how such a trial should be designed so as to maximize yield and avoid mistakes of the past.

  12. Interference of speckle patterns projected by multimode fibers

    NASA Astrophysics Data System (ADS)

    Lomer, M.; Rodriguez-Cobo, L.; Madruga, F.; Lopez-Higuera, J. M.

    2015-08-01

    In this paper, the interference speckle patterns generated by multimode optical fibers are described. In our experience two types of interference are present, random interference between modes propagated in the fiber that give rise to speckle pattern, and not random speckle interference patterns using a Michelson interferometer generating a pattern of conventional interference. Multimode fibers using different materials and core radii have been obtained interference patterns quality characteristic reducing the effects of modal noise in fiber speckle patterns. Experimental results and their potential applications are presented.

  13. A 4MM-Wave composite mode multimode conical feedhorn

    NASA Astrophysics Data System (ADS)

    Lin, Zhisheng; Du, Zhengmi; Chen, Shener

    1996-10-01

    A 4MM-Wave composite mode multimode conical feedhorn has been developed. Its mode-ratios are calculated and its formulas of the radiation patterns are derived. The measurement results of one and two dimension radiation patterns, measured by the automatic measurement system which we had researched, and the properties of band width and sidelobe are given. Theoretical analyses and measurements show that at the centre frequency 69.1GHZ, down to -23dB, the radiation pattern is rotationally symmetric, in this range there is not any sidelobe existing, the band width is 4.5 GHZ. The multimode feedhorn is thus of certain practical using value.

  14. Osm-Oriented Method of Multimodal Route Planning

    NASA Astrophysics Data System (ADS)

    Li, X.; Wu, Q.; Chen, L.; Xiong, W.; Jing, N.

    2015-07-01

    With the increasing pervasiveness of basic facilitate of transportation and information, the need of multimodal route planning is becoming more essential in the fields of communication and transportation, urban planning, logistics management, etc. This article mainly described an OSM-oriented method of multimodal route planning. Firstly, it introduced how to extract the information we need from OSM data and build proper network model and storage model; then it analysed the accustomed cost standard adopted by most travellers; finally, we used shortest path algorithm to calculate the best route with multiple traffic means.

  15. [Principles of fast track surgery. Multimodal perioperative therapy programme].

    PubMed

    Kehlet, H

    2009-08-01

    Recent evidence has documented that a combination of single-modality evidence-based care principles into a multimodal effort to enhance postoperative recovery (the fast track methodology) has led to enhanced recovery with reduced medical morbidity, need for hospitalisation and convalescence. Nevertheless, general implementation of fast track surgery has been relatively slow despite concomitant economic benefits. Further improvement in postoperative outcome may be obtained by developments within each care principle with a specific focus on minimally invasive surgery, effective multimodal, non-opioid analgesia and pharmacological stress reduction.

  16. Multimodal medical information retrieval with unsupervised rank fusion.

    PubMed

    Mourão, André; Martins, Flávio; Magalhães, João

    2015-01-01

    Modern medical information retrieval systems are paramount to manage the insurmountable quantities of clinical data. These systems empower health care experts in the diagnosis of patients and play an important role in the clinical decision process. However, the ever-growing heterogeneous information generated in medical environments poses several challenges for retrieval systems. We propose a medical information retrieval system with support for multimodal medical case-based retrieval. The system supports medical information discovery by providing multimodal search, through a novel data fusion algorithm, and term suggestions from a medical thesaurus. Our search system compared favorably to other systems in 2013 ImageCLEFMedical. Copyright © 2014 Elsevier Ltd. All rights reserved.

  17. Experimental Study on Bioluminescence Tomography with Multimodality Fusion

    PubMed Central

    Lv, Yujie; Tian, Jie; Cong, Wenxiang; Wang, Ge

    2007-01-01

    To verify the influence of a priori information on the nonuniqueness problem of bioluminescence tomography (BLT), the multimodality imaging fusion based BLT experiment is performed by multiview noncontact detection mode, which incorporates the anatomical information obtained by the microCT scanner and the background optical properties based on diffuse reflectance measurements. In the reconstruction procedure, the utilization of adaptive finite element methods (FEMs) and a priori permissible source region refines the reconstructed results and improves numerical robustness and efficiency. The comparison between the absence and employment of a priori information shows that multimodality imaging fusion is essential to quantitative BLT reconstruction. PMID:18256736

  18. Rotary propagation characteristics of light in multimode-single mode-multimode fiber structures using ray tracing method

    NASA Astrophysics Data System (ADS)

    Gao, Hong-yun; Wu, Zi-wei; Xu, Zhe-xiong-yan; Li, Min

    2015-07-01

    The mode theory is the main way to study the propagation characteristics of light in fiber so far, but it is not suitable for analysis of light in duct. By using ray-tracing method, the rotary propagation characteristics of light in multimode-single mode-multimode (MSM) fiber structures are analyzed in this paper. Firstly, the light ray in fiber can propagate around an inscribed circle, and the central axis of this fiber is the propagation axis. Secondly, the radius of the inscribed circle is decided by both incident angle and incident position, and its variation is between 0 and R M, where R M is the radius of the multimode fiber. Lastly, the bigger the ratio of core and cladding diameter is, the higher the propagation efficiency is.

  19. Identifying environmental sounds: a multimodal mapping study

    PubMed Central

    Tomasino, Barbara; Canderan, Cinzia; Marin, Dario; Maieron, Marta; Gremese, Michele; D'Agostini, Serena; Fabbro, Franco; Skrap, Miran

    2015-01-01

    Our environment is full of auditory events such as warnings or hazards, and their correct recognition is essential. We explored environmental sounds (ES) recognition in a series of studies. In study 1 we performed an Activation Likelihood Estimation (ALE) meta-analysis of neuroimaging experiments addressing ES processing to delineate the network of areas consistently involved in ES processing. Areas consistently activated in the ALE meta-analysis were the STG/MTG, insula/rolandic operculum, parahippocampal gyrus and inferior frontal gyrus bilaterally. Some of these areas truly reflect ES processing, whereas others are related to design choices, e.g., type of task, type of control condition, type of stimulus. In study 2 we report on 7 neurosurgical patients with lesions involving the areas which were found to be activated by the ALE meta-analysis. We tested their ES recognition abilities and found an impairment of ES recognition. These results indicate that deficits of ES recognition do not exclusively reflect lesions to the right or to the left hemisphere but both hemispheres are involved. The most frequently lesioned area is the hippocampus/insula/STG. We made sure that any impairment in ES recognition would not be related to language problems, but reflect impaired ES processing. In study 3 we carried out an fMRI study on patients (vs. healthy controls) to investigate how the areas involved in ES might be functionally deregulated because of a lesion. The fMRI evidenced that controls activated the right IFG, the STG bilaterally and the left insula. We applied a multimodal mapping approach and found that, although the meta-analysis showed that part of the left and right STG/MTG activation during ES processing might in part be related to design choices, this area was one of the most frequently lesioned areas in our patients, thus highlighting its causal role in ES processing. We found that the ROIs we drew on the two clusters of activation found in the left and in

  20. Sharing Solutions: Persistence and Grounding in Multimodal Collaborative Problem Solving

    ERIC Educational Resources Information Center

    Dillenbourg, Pierre; Traum, David

    2006-01-01

    This article reports on an exploratory study of the relationship between grounding and problem solving in multimodal computer-mediated collaboration. This article examines two different media, a shared whiteboard and a MOO environment that includes a text chat facility. A study was done on how the acknowledgment rate (how often partners give…

  1. Multimodality and Immigrant Children (Response to Marni Binder)

    ERIC Educational Resources Information Center

    Campano, Gerald; Low, David

    2011-01-01

    This response to Marni Binder reflects upon two examples of (im)migrant children's artwork and challenges the dominant notion that (im)migration experiences--and their subsequent portrayals--can be fit into neat slots. The authors position multimodal composing opportunities as affording children a vital instrument for deploying their full semiotic…

  2. Multimodality and Immigrant Children (Response to Marni Binder)

    ERIC Educational Resources Information Center

    Campano, Gerald; Low, David

    2011-01-01

    This response to Marni Binder reflects upon two examples of (im)migrant children's artwork and challenges the dominant notion that (im)migration experiences--and their subsequent portrayals--can be fit into neat slots. The authors position multimodal composing opportunities as affording children a vital instrument for deploying their full semiotic…

  3. Reading Multimodal Texts: Perceptual, Structural and Ideological Perspectives

    ERIC Educational Resources Information Center

    Serafini, Frank

    2010-01-01

    This article presents a tripartite framework for analyzing multimodal texts. The three analytical perspectives presented include: (1) perceptual, (2) structural, and (3) ideological analytical processes. Using Anthony Browne's picturebook "Piggybook" as an example, assertions are made regarding what each analytical perspective brings to the…

  4. "Convince Me!" Valuing Multimodal Literacies and Composing Public Service Announcements

    ERIC Educational Resources Information Center

    Selfe, Richard J.; Selfe, Cynthia L.

    2008-01-01

    For some teachers, the increasing attention to digital and multimodal composing in English and Language Arts classrooms has brought into sharp relief the profession's investment in print as the primary means of expression. Although new forms of communication that combine words, still and moving images, and animation have begun to dominate digital…

  5. Multimodal Science Teachers' Discourse in Modeling the Water Cycle

    ERIC Educational Resources Information Center

    Marquez, Conxita; Izquierdo, Merce; Espinet, Mariona

    2006-01-01

    The paper presents an intensive study of a micro-event aiming at the characterization of teacher's discourse from a multimodal communication perspective in a secondary school science classroom dealing with the topic of "water cycle." The research addresses the following questions: (a) What communicative modes are used by the teacher?, (b) what…

  6. Highly efficient multimode diode-pumped Yb:KYW laser

    NASA Astrophysics Data System (ADS)

    Kuznetsov, S. A.; Pivtsov, V. S.; Semenko, A. V.; Bagayev, S. N.

    2017-01-01

    Record high differential efficiency (53.2%) and full optical efficiency (48%) for a multimode diode-pumped Yb:KYW laser have been achieved. The characteristics of the laser and methods for improving its efficiency using a distributed Bragg reflector tapered diode laser (DBR TDL) are discussed.

  7. Multimodal Geographic Information Systems: Adding Haptic and Auditory Displays.

    ERIC Educational Resources Information Center

    Jeong, Wooseob

    2001-01-01

    This study consists of two experiments. Pitch, volume, and tempo in auditory-haptic geographic information systems were compared in terms of effectiveness for multimodal interface; volume was determined to be better. Auditory display with volume and haptic display with vibration were compared and the results showed that, in more complex geographic…

  8. Multimodal Bivariate Thematic Maps: Auditory and Haptic Display.

    ERIC Educational Resources Information Center

    Jeong, Wooseob; Gluck, Myke

    2002-01-01

    Explores the possibility of multimodal bivariate thematic maps by utilizing auditory and haptic (sense of touch) displays. Measured completion time of tasks and the recall (retention) rate in two experiments, and findings confirmed the possibility of using auditory and haptic displays in geographic information systems (GIS). (Author/LRW)

  9. Multimodal Geographic Information Systems: Adding Haptic and Auditory Display.

    ERIC Educational Resources Information Center

    Jeong, Wooseob; Gluck, Myke

    2003-01-01

    Investigated the feasibility of adding haptic and auditory displays to traditional visual geographic information systems (GISs). Explored differences in user performance, including task completion time and accuracy, and user satisfaction with a multimodal GIS which was implemented with a haptic display, auditory display, and combined display.…

  10. Transmodal Redesign in Music and Literacy: Diverse Multimodal Classrooms

    ERIC Educational Resources Information Center

    Tomlinson, Michelle M.

    2015-01-01

    Two classrooms of diverse 5-year-old children were set the task of exploring ways of realising music invention through the semiotic import of composing resources. In both a rural and an inner-urban setting in Australia, children demonstrated syncretism in bilingual practices in communication. Visual multimodal analysis demonstrated how children…

  11. Border Crossings and Multimodal Composition in the Arts

    ERIC Educational Resources Information Center

    Morrison, Andrew

    2005-01-01

    Developmental and development-oriented learning with digital media are discussed in relation to the concepts border crossings and multimodal composition. The first concept refers to a transveral of disciplines and recombinations of elements from them. Local-global relations in knowledge building are covered. The second refers to the collaborative…

  12. Multimodality Approach to Methadone Treatment of Narcotic Addicts

    ERIC Educational Resources Information Center

    Brill, Leon; Chambers, Carl D.

    1971-01-01

    This multimodality approach is geared primarily to the goal of abstinence. For addicts who cannot achieve this goal, methadone maintenance is suggested as the next step. The modalities described range from low-dose maintenance for clinic outpatients to intensive rehabilitation in a methadone maintenance residential center facility. (Author)

  13. Norms of quantum Gaussian multi-mode channels

    NASA Astrophysics Data System (ADS)

    Frank, Rupert L.; Lieb, Elliott H.

    2017-06-01

    We compute the Sp→Sp norm of a general Gaussian gauge-covariant multi-mode channel for any 1 ≤ p < ∞ , where Sp is a Schatten space. As a consequence, we verify the Gaussian optimizer conjecture and the multiplicativity conjecture in these cases.

  14. Multimodal Analgesia, Current Concepts, and Acute Pain Considerations.

    PubMed

    Helander, Erik M; Menard, Bethany L; Harmon, Chris M; Homra, Ben K; Allain, Alexander V; Bordelon, Gregory J; Wyche, Melville Q; Padnos, Ira W; Lavrova, Anna; Kaye, Alan D

    2017-01-01

    Management of acute pain following surgery using a multimodal approach is recommended by the American Society of Anesthesiologists whenever possible. In addition to opioids, drugs with differing mechanisms of actions target pain pathways resulting in additive and/or synergistic effects. Some of these agents include alpha 2 agonists, NMDA receptor antagonists, gabapentinoids, dexamethasone, NSAIDs, acetaminophen, and duloxetine. Alpha 2 agonists have been shown to have opioid-sparing effects, but can cause hypotension and bradycardia and must be taken into consideration when administered. Acetaminophen is commonly used in a multimodal approach, with recent evidence lacking for the use of IV over oral formulations in patients able to take medications by mouth. Studies involving gabapentinoids have been mixed with some showing benefit; however, future large randomized controlled trials are needed. Ketamine is known to have powerful analgesic effects and, when combined with magnesium and other agents, may have a synergistic effect. Dexamethasone reduces postoperative nausea and vomiting and has been demonstrated to be an effective adjunct in multimodal analgesia. The serotonin-norepinephrine reuptake inhibitor, duloxetine, is a novel agent, but studies are limited and further evidence is needed. Overall, a multimodal analgesic approach should be used when treating postoperative pain, as it can potentially reduce side effects and provide the benefit of treating pain through different cellular pathways.

  15. [Multimodal pain therapy in Germany: structure and quality].

    PubMed

    Casser, Hans-Raimund; Nagel, Bernd

    2016-01-01

    Multimodal Pain Management is a comprehensive treatment of complex chronic pain syndromes. In addition to medical therapy various other specialized therapeutical interventions based on the biopsychosocial model of pain origin and chronic pain development are added.Medical indications are given for patients with chronic pain syndromes, but also if there is an elevated risk of chronic pain in the early stadium of the disease and aiming at delaying the process of chronification. Multimodal pain management has been included in the official catalogue of the recognized medical procedure for day clinic units as well as for inpatients pain management. As there is still a lack of clarity and of consistency about the implementation of multimodal pain management the ad-hoc-Kommission on multimodal interdisciplinary pain management of the German Pain Society has proposed a position paper that has been worked out in a multilevel and interdisciplinary consensus process. Moreover a basic tool for documentation and quality management of pain therapy was developed by the German Pain Society (KEDOQ-Schmerz) as the data basis for nationwide, cross-sectional and independent scientific research in health services in Germany. In future KEDOQ-Schmerz will also used as a method for external quality management in chronic pain therapy in Germany. © Georg Thieme Verlag Stuttgart · New York.

  16. Drawing Near and Pushing Away: Critical Positioning in Multimodal Composition

    ERIC Educational Resources Information Center

    Doerr-Stevens, Candance

    2016-01-01

    As the tools and modes of literate practice continually emerge, so too must our critical approaches to understanding their expression. While media production has been praised for its potential to provide youth a voice to challenge dominant narratives, various questions remain as to what happens at the multimodal levels of composition in terms of…

  17. Multimodal MRI classification in vascular mild cognitive impairment.

    PubMed

    Diciotti, Stefano; Ciulli, Stefano; Ginestroni, Andrea; Salvadori, Emilia; Poggesi, Anna; Pantoni, Leonardo; Inzitari, Domenico; Mascalchi, Mario; Toschi, Nicola

    2015-08-01

    Vascular mild cognitive impairment (VMCI) is a disorder in which multimodal MRI can add significant value by combining diffusion tensor imaging (DTI) with brain morphometry. In this study we implemented and compared machine learning techniques for multimodal classification between 58 VMCI patients and 29 healthy subjects as well as for discrimination (within the VMCI group) between patients with different cognitive performances. For each subject, a cortical feature vector was constructed based on cortical parcellation and cortical and subcortical volumetric segmentation and a DTI feature vector was formed by combining descriptive statistical metrics related to the distribution of DTI invariants within white matter. We employed both a sequential minimal optimization and a functional tree classifier, using feature selection and 10-fold cross-validation, and compared their performances in monomodal and multimodal classification for both classification problems (healthy subjects vs VMCI and prediction of cognitive performance). While monomodal classification resulted in satisfactory performance in most cases, turning from monomodal to multimodal classification resulted in an improvement of the performance in the discrimination between VMCI patients with low cognitive performance and healthy subjects by up to 10% in sensitivity (leaving specificity unchanged). We therefore are able to confirm the usefulness of machine learning techniques in discriminating diseased states based on neuroimaging data.

  18. Challenges in Transcribing Multimodal Data: A Case Study

    ERIC Educational Resources Information Center

    Helm, Francesca; Dooly, Melinda

    2017-01-01

    Computer-mediated communication (CMC) once meant principally text-based communication mediated by computers, but rapid technological advances in recent years have heralded an era of multimodal communication with a growing emphasis on audio and video synchronous interaction. As CMC, in all its variants (text chats, video chats, forums, blogs, SMS,…

  19. Multimodal Play and Adolescents: Notes on Noticing Laughter

    ERIC Educational Resources Information Center

    Vasudevan, Lalitha

    2015-01-01

    In this article, I explore laughter as a form of multimodal play in which adolescents' engage across contexts and in various configurations. With a few recent exceptions, a focus on unscripted play is largely missing from ongoing research and discussion about the education of adolescents. Whereas the space to play has been vitally important to the…

  20. "Rap Universal": Using Multimodal Media Production to Develop ICT Literacies

    ERIC Educational Resources Information Center

    Turner, K. C. Nat

    2011-01-01

    Through a multimodal media production literacy intervention in an extended-day program, culturally and linguistically diverse youth developed valuable information and communication technology literacies, including: (1) Specific how-to skills useful in future academic, professional, social, and civic contexts; (2) Abilities to critically interpret…

  1. Shrek Meets Vygotsky: Rethinking Adolescents' Multimodal Literacy Practices in Schools

    ERIC Educational Resources Information Center

    Mills, Kathy A.

    2010-01-01

    Recent research has emphasized the multimodal and digital nature of adolescent literacy practices. These practices cross multiple social spaces, particularly settings outside of schools. This article re-examines current research to yield three caveats that counter assumptions about the pervasiveness, relevance, and spontaneity of youths'…

  2. Learning from Picturebooks: Reading and Writing Multimodally in First Grade

    ERIC Educational Resources Information Center

    Martens, Prisca; Martens, Ray; Doyle, Michelle Hassay; Loomis, Jenna; Aghalarov, Stacy

    2013-01-01

    This article shares the authors' work with first graders and how, through various reading, writing, and art experiences around picturebooks, the children learned to read and communicate through art along with written language. The work is grounded in multimodality theory and the belief that all modes (particularly art for the purposes of this…

  3. Speckle reduction in OCT with multimode source fiber

    NASA Astrophysics Data System (ADS)

    Kim, Jeehyun; Kim, Eunha K.; Miller, Donald T.; Milner, Thomas E.

    2004-06-01

    Speckle noise in OCT images originates in the high spatial coherence that allows interference between light backscattered from the tissue specimen. Speckle reduction techniques on which many investigators have reported all rely on averaging independent intensity images of the speckle field. Recently, we completed an experiment to test speckle reduction by averaging independent intensity images formed by incoherent spatial modes emitted from a broadband light source. Broadband light coupled into a multimode optical fiber produces a number of spatial modes that propagate along the waveguide at distinct velocities. When the spatial modes propagate length, modes become mutually incoherent. When the multimode fiber is placed in the source path of a Michelson interferometer, each spatial mode produces an intensity image of an independent speckle field. To illustrate speckle averaging using independent spatial modes, we recorded low-coherence interferograms of a scattering metallic surface using single mode and multimode source fiber. The interferogram recorded using a single mode source fiber is indicative of that observed by conventional OCT. Speckle noise in the interferogram recorded using the multimode source fiber is substantially reduced compared to the single mode case.

  4. Multi-modal CT in Stroke Imaging: New Concepts

    PubMed Central

    Ledezma, Carlos J.; Wintermark, Max

    2009-01-01

    A multimodal CT protocol provides a comprehensive non-invasive survey of acute stroke patients with accurate demonstration of the site of arterial occlusion and its hemodynamic tissue status. It combines widespread availability with the ability to provide functional characterization of cerebral ischemia, and could potentially allow more accurate selection of candidates for acute stroke reperfusion therapy. PMID:19195537

  5. Severe Speech Sound Disorders: An Integrated Multimodal Intervention

    ERIC Educational Resources Information Center

    King, Amie M.; Hengst, Julie A.; DeThorne, Laura S.

    2013-01-01

    Purpose: This study introduces an integrated multimodal intervention (IMI) and examines its effectiveness for the treatment of persistent and severe speech sound disorders (SSD) in young children. The IMI is an activity-based intervention that focuses simultaneously on increasing the "quantity" of a child's meaningful productions of target words…

  6. Children Creating Multimodal Stories about a Familiar Environment

    ERIC Educational Resources Information Center

    Kervin, Lisa; Mantei, Jessica

    2017-01-01

    Storytelling is a practice that enables children to apply their literacy skills. This article shares a collaborative literacy strategy devised to enable children to create multimodal stories about their familiar school environment. The strategy uses resources, including the children's own drawings, images from Google Maps, and the Puppet Pals…

  7. A Sense of Audience in Young Children's Multimodal Information Books

    ERIC Educational Resources Information Center

    Dong, Hongmei

    2010-01-01

    Elementary children's sense of audience related to their multimodal information writing was examined. Forty-six third graders' interviews about the books that they created at the end of a science unit were analyzed to understand children's conception of audience, the connection between their sense of audience and their composing process, and their…

  8. A Multimodal Neural Network Recruited by Expertise with Musical Notation

    ERIC Educational Resources Information Center

    Wong, Yetta Kwailing; Gauthier, Isabel

    2010-01-01

    Prior neuroimaging work on visual perceptual expertise has focused on changes in the visual system, ignoring possible effects of acquiring expert visual skills in nonvisual areas. We investigated expertise for reading musical notation, a skill likely to be associated with multimodal abilities. We compared brain activity in music-reading experts…

  9. Connecting, Creating and Composing: A Shared Multimodal Journey

    ERIC Educational Resources Information Center

    Krause, Margaret B.

    2015-01-01

    Given the dynamic nature of our society, literacy conceptualizations are constantly being redefined. While print literacy continues to be the primary literacy within elementary classroom, the growing nature of technological capabilities, social networking, and multimodal affordances require educators to delve into explorations of how children can…

  10. Transnational Children Orchestrating Competing Voices in Multimodal, Digital Autobiographies

    ERIC Educational Resources Information Center

    Pandya, Jessica Zacher; Pagdilao, Kathleah Consul; Kim, Enok Aeloch

    2015-01-01

    Background/Context: Prior research on multimodal, digital composition has highlighted the need for educators to bring such practices into classrooms, yet little research has been done to show what kinds of products children create and what those products can tell us as researchers about how children articulate their life experiences. We draw on…

  11. A Multimodal Approach in Dealing with Older Clients.

    ERIC Educational Resources Information Center

    Weikel, William J.

    1990-01-01

    Notes that older persons underuse community-based and outpatient mental health services, yet are overrepresented in inpatient facilities. Argues for increased programing targeted for elderly client. Advocates use of multimodal model as efficient method of service delivery and provides sample case study using BASIC ID (Behavior, Affect, Sensation,…

  12. Shrek Meets Vygotsky: Rethinking Adolescents' Multimodal Literacy Practices in Schools

    ERIC Educational Resources Information Center

    Mills, Kathy A.

    2010-01-01

    Recent research has emphasized the multimodal and digital nature of adolescent literacy practices. These practices cross multiple social spaces, particularly settings outside of schools. This article re-examines current research to yield three caveats that counter assumptions about the pervasiveness, relevance, and spontaneity of youths'…

  13. Multi-modal locomotion: from animal to application.

    PubMed

    Lock, R J; Burgess, S C; Vaidyanathan, R

    2014-03-01

    The majority of robotic vehicles that can be found today are bound to operations within a single media (i.e. land, air or water). This is very rarely the case when considering locomotive capabilities in natural systems. Utility for small robots often reflects the exact same problem domain as small animals, hence providing numerous avenues for biological inspiration. This paper begins to investigate the various modes of locomotion adopted by different genus groups in multiple media as an initial attempt to determine the compromise in ability adopted by the animals when achieving multi-modal locomotion. A review of current biologically inspired multi-modal robots is also presented. The primary aim of this research is to lay the foundation for a generation of vehicles capable of multi-modal locomotion, allowing ambulatory abilities in more than one media, surpassing current capabilities. By identifying and understanding when natural systems use specific locomotion mechanisms, when they opt for disparate mechanisms for each mode of locomotion rather than using a synergized singular mechanism, and how this affects their capability in each medium, similar combinations can be used as inspiration for future multi-modal biologically inspired robotic platforms.

  14. Comprehension Strategy Instruction for Multimodal Texts in Science

    ERIC Educational Resources Information Center

    Alvermann, Donna E.; Wilson, Amy Alexandra

    2011-01-01

    This article highlights examples from a middle-school science teacher's instruction using multimodal texts. Its importance lies in reconciling narrowed definitions of reading (and hence reading instruction) with the need to develop students' critical awareness as they engage with multiple sign systems, or semiotic resources, used for constructing…

  15. Utilizing Multi-Modal Literacies in Middle Grades Science

    ERIC Educational Resources Information Center

    Saurino, Dan; Ogletree, Tamra; Saurino, Penelope

    2010-01-01

    The nature of literacy is changing. Increased student use of computer-mediated, digital, and visual communication spans our understanding of adolescent multi-modal capabilities that reach beyond the traditional conventions of linear speech and written text in the science curriculum. Advancing technology opens doors to learning that involve…

  16. Multimodal Composition and the Common Core State Standards

    ERIC Educational Resources Information Center

    Dalton, Bridget

    2013-01-01

    The Common Core State Standards call for an expanded view of literacy instruction, one where children learn to critically consume and produce text using technology and media. This article describes how a Digital Writers' Workshop can be a vehicle for integrating multimodal composition into the classroom. It offers general workshop principles and…

  17. A Plurisemiotic Study of Multimodal Interactive Teaching through Videoconferencing

    ERIC Educational Resources Information Center

    Codreanu, Tatiana; Celik, Christelle Combe

    2012-01-01

    The aim of the study is to describe and analyze webcam pedagogical communication between a French Foreign Language tutor and two students during seven online classes. It tries to answer the following question: how does the tutor in a multimodal learning environment change her semio-discursive behavior from the first to the last session? We analyze…

  18. Transnational Children Orchestrating Competing Voices in Multimodal, Digital Autobiographies

    ERIC Educational Resources Information Center

    Pandya, Jessica Zacher; Pagdilao, Kathleah Consul; Kim, Enok Aeloch

    2015-01-01

    Background/Context: Prior research on multimodal, digital composition has highlighted the need for educators to bring such practices into classrooms, yet little research has been done to show what kinds of products children create and what those products can tell us as researchers about how children articulate their life experiences. We draw on…

  19. Designing Is Learning: An Investigation of Designing Multimodal Texts

    ERIC Educational Resources Information Center

    Hall, Matthew

    2013-01-01

    This qualitative study analyzed the meaning-making practices of urban adolescents participating in a college preparatory program featuring philosophical inquiry into cosmopolitanism and the creation of multimodal texts. In contrast to studies of composing that focus on individual outcomes, this dissertation traced group meaning making. The study…

  20. Learning through Story: A Collaborative, Multimodal Arts Approach

    ERIC Educational Resources Information Center

    Barton, Georgina; Baguley, Margaret

    2014-01-01

    Literate practice in the arts encompasses both aesthetics and creativity. It is also multimodal in nature and often collaborative. This article presents data collected from a small multi-age school, with children from Prep to Year 7, during their preparation for an end-of-year show. The children had studied the topics of conservation and…

  1. Learning to Teach Generative Meaning-Making through Multimodal Inquiry

    ERIC Educational Resources Information Center

    Loretto, Adam; Chisholm, James S.

    2012-01-01

    This classroom narrative describes the transformation of one beginning English/language arts (ELA) teacher's perspective and practice as the teacher enacted multimodal inquiry activities that were the focus of both traditional and action research projects. Drawing on field notes, transcripts of classroom discourse, and student-produced artefacts,…

  2. Learning from Picturebooks: Reading and Writing Multimodally in First Grade

    ERIC Educational Resources Information Center

    Martens, Prisca; Martens, Ray; Doyle, Michelle Hassay; Loomis, Jenna; Aghalarov, Stacy

    2013-01-01

    This article shares the authors' work with first graders and how, through various reading, writing, and art experiences around picturebooks, the children learned to read and communicate through art along with written language. The work is grounded in multimodality theory and the belief that all modes (particularly art for the purposes of this…

  3. Multimodal Geographic Information Systems: Adding Haptic and Auditory Display.

    ERIC Educational Resources Information Center

    Jeong, Wooseob; Gluck, Myke

    2003-01-01

    Investigated the feasibility of adding haptic and auditory displays to traditional visual geographic information systems (GISs). Explored differences in user performance, including task completion time and accuracy, and user satisfaction with a multimodal GIS which was implemented with a haptic display, auditory display, and combined display.…

  4. Ultrasonic Motors Using Piezoelectric Ceramic Multi-Mode Vibrators

    NASA Astrophysics Data System (ADS)

    Takano, Takehiro; Tomikawa, Yoshiro; Ogasawara, Toshiharu; Sugawara, Sumio; Konnon, Masashi

    1988-01-01

    The purpose of this paper is to report development of an ultrasonic motor using piezoelectric ceramic multi-mode vibrators of circular or annular plates, in which degenerate horizontal vibration modes of the same or different form are used. Some constructions of the motor and its experimental characteristics are presented. The ultrasonic motor investigated herein shows special merit in its thin construction.

  5. An Examination of ESL Taiwanese University Students' Multimodal Reading Responses

    ERIC Educational Resources Information Center

    Lee, Hsiao-Chien

    2013-01-01

    This article reports an empirical study conducted in a Taiwanese English as a second language university class. Reader response theory is the theoretical framework guiding the study. Fifty-nine university students were encouraged to collaboratively create multimodal responses to a classic English reading. Taking an aesthetic reading stance, the…

  6. Promoting Multilingual Communicative Competence through Multimodal Academic Learning Situations

    ERIC Educational Resources Information Center

    Kyppö, Anna; Natri, Teija

    2016-01-01

    This paper presents information on the factors affecting the development of multilingual and multicultural communicative competence in interactive multimodal learning environments in an academic context. The interdisciplinary course in multilingual interaction offered at the University of Jyväskylä aims to enhance students' competence in…

  7. Discrimination of skin diseases using the multimodal imaging approach

    NASA Astrophysics Data System (ADS)

    Vogler, N.; Heuke, S.; Akimov, D.; Latka, I.; Kluschke, F.; Röwert-Huber, H.-J.; Lademann, J.; Dietzek, B.; Popp, J.

    2012-06-01

    Optical microspectroscopic tools reveal great potential for dermatologic diagnostics in the clinical day-to-day routine. To enhance the diagnostic value of individual nonlinear optical imaging modalities such as coherent anti-Stokes Raman scattering (CARS), second harmonic generation (SHG) or two-photon excited fluorescence (TPF), the approach of multimodal imaging has recently been developed. Here, we present an application of nonlinear optical multimodal imaging with Raman-scattering microscopy to study sizable human-tissue cross-sections. The samples investigated contain both healthy tissue and various skin tumors. This contribution details the rich information content, which can be obtained from the multimodal approach: While CARS microscopy, which - in contrast to spontaneous Raman-scattering microscopy - is not hampered by single-photon excited fluorescence, is used to monitor the lipid and protein distribution in the samples, SHG imaging selectively highlights the distribution of collagen structures within the tissue. This is due to the fact, that SHG is only generated in structures which lack inversion geometry. Finally, TPF reveals the distribution of autofluorophores in tissue. The combination of these techniques, i.e. multimodal imaging, allows for recording chemical images of large area samples and is - as this contribution will highlight - of high clinically diagnostic value.

  8. Drawing Near and Pushing Away: Critical Positioning in Multimodal Composition

    ERIC Educational Resources Information Center

    Doerr-Stevens, Candance

    2016-01-01

    As the tools and modes of literate practice continually emerge, so too must our critical approaches to understanding their expression. While media production has been praised for its potential to provide youth a voice to challenge dominant narratives, various questions remain as to what happens at the multimodal levels of composition in terms of…

  9. A simultaneous multimodal imaging system for tissue functional parameters

    NASA Astrophysics Data System (ADS)

    Ren, Wenqi; Zhang, Zhiwu; Wu, Qiang; Zhang, Shiwu; Xu, Ronald

    2014-02-01

    Simultaneous and quantitative assessment of skin functional characteristics in different modalities will facilitate diagnosis and therapy in many clinical applications such as wound healing. However, many existing clinical practices and multimodal imaging systems are subjective, qualitative, sequential for multimodal data collection, and need co-registration between different modalities. To overcome these limitations, we developed a multimodal imaging system for quantitative, non-invasive, and simultaneous imaging of cutaneous tissue oxygenation and blood perfusion parameters. The imaging system integrated multispectral and laser speckle imaging technologies into one experimental setup. A Labview interface was developed for equipment control, synchronization, and image acquisition. Advanced algorithms based on a wide gap second derivative reflectometry and laser speckle contrast analysis (LASCA) were developed for accurate reconstruction of tissue oxygenation and blood perfusion respectively. Quantitative calibration experiments and a new style of skinsimulating phantom were designed to verify the accuracy and reliability of the imaging system. The experimental results were compared with a Moor tissue oxygenation and perfusion monitor. For In vivo testing, a post-occlusion reactive hyperemia (PORH) procedure in human subject and an ongoing wound healing monitoring experiment using dorsal skinfold chamber models were conducted to validate the usability of our system for dynamic detection of oxygenation and perfusion parameters. In this study, we have not only setup an advanced multimodal imaging system for cutaneous tissue oxygenation and perfusion parameters but also elucidated its potential for wound healing assessment in clinical practice.

  10. Transmodal Redesign in Music and Literacy: Diverse Multimodal Classrooms

    ERIC Educational Resources Information Center

    Tomlinson, Michelle M.

    2015-01-01

    Two classrooms of diverse 5-year-old children were set the task of exploring ways of realising music invention through the semiotic import of composing resources. In both a rural and an inner-urban setting in Australia, children demonstrated syncretism in bilingual practices in communication. Visual multimodal analysis demonstrated how children…

  11. Connecting, Creating and Composing: A Shared Multimodal Journey

    ERIC Educational Resources Information Center

    Krause, Margaret B.

    2015-01-01

    Given the dynamic nature of our society, literacy conceptualizations are constantly being redefined. While print literacy continues to be the primary literacy within elementary classroom, the growing nature of technological capabilities, social networking, and multimodal affordances require educators to delve into explorations of how children can…

  12. Beyond Talking Heads: Sourced Comics and the Affordances of Multimodality

    ERIC Educational Resources Information Center

    Dickinson, Hannah; Werner, Maggie M.

    2015-01-01

    This article analyzes the genre of the sourced comic as an important pedagogical tool in the development of both alphabetic and multimodal literacies. We argue that sourced comics provide multiple design elements with which students can explore their complex relationships with scholarly sources, make visible various power relations informing…

  13. A Springboard Rather than a Bridge: Diving into Multimodal Literacy

    ERIC Educational Resources Information Center

    Graham, Meadow Sherrill; Benson, Sheila

    2010-01-01

    In the authors' experience as teacher educators, many preservice teachers view literacy as a print-bound process. With multimodal literacy becoming more important as many states push for 21st-century learning standards, the authors are always looking for ways to help students break their concepts of literacy away from the printed page. As they…

  14. "Imaginings": Reflections on Plurilingual Students' Creative Multimodal Works

    ERIC Educational Resources Information Center

    Stille, Saskia; Prasad, Gail

    2015-01-01

    The purpose of this article is to illustrate the potential contribution of a multimodal approach to English language teaching and learning in the educational context. Collaborating with English as a second language (ESL) and classroom teachers to explore ways to improve pedagogy in multilingual, multicultural schools, the authors discovered many…

  15. Berlin Kompass: Multimodal Gameful Empowerment for Foreign Language Learning

    ERIC Educational Resources Information Center

    Kallioniemi, Pekka; Posti, Laura-Pihkala; Hakulinen, Jaakko; Turunen, Markku; Keskinen, Tuuli; Raisamo, Roope

    2015-01-01

    This article presents an innovative, gameful, multimodal, and authentic learning environment for training of oral communication in a foreign language--a virtual adventure called Berlin Kompass. After a brief presentation of the pedagogical and technological backgrounds, the system is described. Central results of a series of pilots in autumn 2013…

  16. Designing Is Learning: An Investigation of Designing Multimodal Texts

    ERIC Educational Resources Information Center

    Hall, Matthew

    2013-01-01

    This qualitative study analyzed the meaning-making practices of urban adolescents participating in a college preparatory program featuring philosophical inquiry into cosmopolitanism and the creation of multimodal texts. In contrast to studies of composing that focus on individual outcomes, this dissertation traced group meaning making. The study…

  17. Multimodal Counseling of Childhood Encopresis: A Case Example.

    ERIC Educational Resources Information Center

    Gumaer, Jim

    1990-01-01

    Provides information regarding childhood disorder of encopresis and presents multimodal therapy techniques for school counselors who cannot successfully refer clients. Presents a case study of a teenage boy suffering from encopresis who was referred for counseling. Suggests specific treatment strategies including behavior modification, nutrition…

  18. Reading Multimodal Texts: Perceptual, Structural and Ideological Perspectives

    ERIC Educational Resources Information Center

    Serafini, Frank

    2010-01-01

    This article presents a tripartite framework for analyzing multimodal texts. The three analytical perspectives presented include: (1) perceptual, (2) structural, and (3) ideological analytical processes. Using Anthony Browne's picturebook "Piggybook" as an example, assertions are made regarding what each analytical perspective brings to the…

  19. Multimodal Geographic Information Systems: Adding Haptic and Auditory Displays.

    ERIC Educational Resources Information Center

    Jeong, Wooseob

    2001-01-01

    This study consists of two experiments. Pitch, volume, and tempo in auditory-haptic geographic information systems were compared in terms of effectiveness for multimodal interface; volume was determined to be better. Auditory display with volume and haptic display with vibration were compared and the results showed that, in more complex geographic…

  20. Orchestrating Literacies: Print Literacy Learning Opportunities within Multimodal Intergenerational Ensembles

    ERIC Educational Resources Information Center

    McKee, Lori L.; Heydon, Rachel M.

    2015-01-01

    This exploratory case study considered the opportunities for print literacy learning within multimodal ensembles that featured art, singing and digital media within the context of an intergenerational programme that brought together 13 kindergarten children (4 and 5 years) with seven elder companions. Study questions concerned how reading and…

  1. "Rap Universal": Using Multimodal Media Production to Develop ICT Literacies

    ERIC Educational Resources Information Center

    Turner, K. C. Nat

    2011-01-01

    Through a multimodal media production literacy intervention in an extended-day program, culturally and linguistically diverse youth developed valuable information and communication technology literacies, including: (1) Specific how-to skills useful in future academic, professional, social, and civic contexts; (2) Abilities to critically interpret…

  2. Multimodality in Malaysian Schools: The Case for the Graphic Novel

    ERIC Educational Resources Information Center

    Rajendra, Thusha Rani

    2015-01-01

    This paper aims at exploring the benefits of including graphic novels as a wholesome supplement in Malaysian schools. Research has indicated that the mono-modality of traditional linear texts may impede comprehension. The emphasis on multi-literacies clearly scaffold the need to employ multimodality in the classrooms; hence the suggestion of…

  3. Podcasting and Performativity: Multimodal Invention in an Advanced Writing Class

    ERIC Educational Resources Information Center

    Jones, Leigh A.

    2010-01-01

    This article points composition scholars toward two bodies of theory that are gaining attention in our discipline, performance studies and multimodal discourse theory. Each raises important questions about the ways we teach writing, the kinds of composition processes we value, and the means by which students construct authority in the university.…

  4. A Mediated Discourse Analysis (MDA) Approach to Multimodal Data

    ERIC Educational Resources Information Center

    Dooly, Melinda

    2017-01-01

    Just as research in language learning is moving beyond the four walls of the classroom, there is a growing awareness that language use (and simultaneous learning) takes place in increasingly complex and interconnected ways, in particular through the use of technology. This chapter summarizes an investigation into multimodal communicative…

  5. Wavelength tuning of fiber lasers using multimode interference effects.

    PubMed

    Selvas, R; Torres-Gomez, I; Martinez-Rios, A; Alvarez-Chavez, J; May-Arrioja, D; Likamwa, P; Mehta, A; Johnson, E

    2005-11-14

    We report on a novel scheme to fabricate a simple, cheap, and compact tunable fiber laser. The tuning is realized by splicing a piece of single-mode fiber to one end of an active double-clad fiber, while the other end of the single-mode fiber is spliced to a 15 mm long section of 105/125 multimode fiber. The fluorescence signal entering into the multimode fiber will be reproduced as single images at periodic intervals along the propagation direction of the fiber. The length of the multimode fiber is chosen to be slightly shorter than the first re-imaging point, such that the signal coming out from the single mode fiber is obtained in free space, where a broadband mirror retroreflects the fluorescence signal. Since the position of the re-imaging point is wavelength dependent, different wavelengths will be imaged at different positions. Therefore, wavelength tuning is easily obtained by adjusting the distance between the broadband mirror and the multimode fiber facet end. Using this principle, the tunable fiber laser revealed a tunability of 8 nm, ranging from 1088-1097 nm, and an output power of 500 mW. The simplicity of the setup makes this a very cost-effective tunable fiber laser.

  6. Multimodal Composition and the Common Core State Standards

    ERIC Educational Resources Information Center

    Dalton, Bridget

    2013-01-01

    The Common Core State Standards call for an expanded view of literacy instruction, one where children learn to critically consume and produce text using technology and media. This article describes how a Digital Writers' Workshop can be a vehicle for integrating multimodal composition into the classroom. It offers general workshop principles and…

  7. A Multimodal Neural Network Recruited by Expertise with Musical Notation

    ERIC Educational Resources Information Center

    Wong, Yetta Kwailing; Gauthier, Isabel

    2010-01-01

    Prior neuroimaging work on visual perceptual expertise has focused on changes in the visual system, ignoring possible effects of acquiring expert visual skills in nonvisual areas. We investigated expertise for reading musical notation, a skill likely to be associated with multimodal abilities. We compared brain activity in music-reading experts…

  8. Multimodal imaging of lung cancer and its microenvironment (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Hariri, Lida P.; Niederst, Matthew J.; Mulvey, Hillary; Adams, David C.; Hu, Haichuan; Chico Calero, Isabel; Szabari, Margit V.; Vakoc, Benjamin J.; Hasan, Tayyaba; Bouma, Brett E.; Engelman, Jeffrey A.; Suter, Melissa J.

    2016-03-01

    Despite significant advances in targeted therapies for lung cancer, nearly all patients develop drug resistance within 6-12 months and prognosis remains poor. Developing drug resistance is a progressive process that involves tumor cells and their microenvironment. We hypothesize that microenvironment factors alter tumor growth and response to targeted therapy. We conducted in vitro studies in human EGFR-mutant lung carcinoma cells, and demonstrated that factors secreted from lung fibroblasts results in increased tumor cell survival during targeted therapy with EGFR inhibitor, gefitinib. We also demonstrated that increased environment stiffness results in increased tumor survival during gefitinib therapy. In order to test our hypothesis in vivo, we developed a multimodal optical imaging protocol for preclinical intravital imaging in mouse models to assess tumor and its microenvironment over time. We have successfully conducted multimodal imaging of dorsal skinfold chamber (DSC) window mice implanted with GFP-labeled human EGFR mutant lung carcinoma cells and visualized changes in tumor development and microenvironment facets over time. Multimodal imaging included structural OCT to assess tumor viability and necrosis, polarization-sensitive OCT to measure tissue birefringence for collagen/fibroblast detection, and Doppler OCT to assess tumor vasculature. Confocal imaging was also performed for high-resolution visualization of EGFR-mutant lung cancer cells labeled with GFP, and was coregistered with OCT. Our results demonstrated that stromal support and vascular growth are essential to tumor progression. Multimodal imaging is a useful tool to assess tumor and its microenvironment over time.

  9. Beyond Talking Heads: Sourced Comics and the Affordances of Multimodality

    ERIC Educational Resources Information Center

    Dickinson, Hannah; Werner, Maggie M.

    2015-01-01

    This article analyzes the genre of the sourced comic as an important pedagogical tool in the development of both alphabetic and multimodal literacies. We argue that sourced comics provide multiple design elements with which students can explore their complex relationships with scholarly sources, make visible various power relations informing…

  10. Comprehension Strategy Instruction for Multimodal Texts in Science

    ERIC Educational Resources Information Center

    Alvermann, Donna E.; Wilson, Amy Alexandra

    2011-01-01

    This article highlights examples from a middle-school science teacher's instruction using multimodal texts. Its importance lies in reconciling narrowed definitions of reading (and hence reading instruction) with the need to develop students' critical awareness as they engage with multiple sign systems, or semiotic resources, used for constructing…

  11. A multimeric MR-optical contrast agent for multimodal imaging†

    PubMed Central

    Harrison, Victoria S. R.; Carney, Christiane E.; Macrenaris, Keith W.

    2015-01-01

    We describe the design, synthesis and in vitro evaluation of a multimodal and multimeric contrast agent. The agent consists of three macrocyclic Gd(III) chelates conjugated to a fluorophore and possesses high relaxivity, water solubility, and is nontoxic. The modular synthesis is amenable for the incorporation of a variety of fluorophores to generate molecular constructs for a number of applications. PMID:25137290

  12. Multimodal Counseling of Childhood Encopresis: A Case Example.

    ERIC Educational Resources Information Center

    Gumaer, Jim

    1990-01-01

    Provides information regarding childhood disorder of encopresis and presents multimodal therapy techniques for school counselors who cannot successfully refer clients. Presents a case study of a teenage boy suffering from encopresis who was referred for counseling. Suggests specific treatment strategies including behavior modification, nutrition…

  13. "Imaginings": Reflections on Plurilingual Students' Creative Multimodal Works

    ERIC Educational Resources Information Center

    Stille, Saskia; Prasad, Gail

    2015-01-01

    The purpose of this article is to illustrate the potential contribution of a multimodal approach to English language teaching and learning in the educational context. Collaborating with English as a second language (ESL) and classroom teachers to explore ways to improve pedagogy in multilingual, multicultural schools, the authors discovered many…

  14. Multimodality Approach to Methadone Treatment of Narcotic Addicts

    ERIC Educational Resources Information Center

    Brill, Leon; Chambers, Carl D.

    1971-01-01

    This multimodality approach is geared primarily to the goal of abstinence. For addicts who cannot achieve this goal, methadone maintenance is suggested as the next step. The modalities described range from low-dose maintenance for clinic outpatients to intensive rehabilitation in a methadone maintenance residential center facility. (Author)

  15. Multimodal Science Teachers' Discourse in Modeling the Water Cycle

    ERIC Educational Resources Information Center

    Marquez, Conxita; Izquierdo, Merce; Espinet, Mariona

    2006-01-01

    The paper presents an intensive study of a micro-event aiming at the characterization of teacher's discourse from a multimodal communication perspective in a secondary school science classroom dealing with the topic of "water cycle." The research addresses the following questions: (a) What communicative modes are used by the teacher?, (b) what…

  16. Orchestrating Literacies: Print Literacy Learning Opportunities within Multimodal Intergenerational Ensembles

    ERIC Educational Resources Information Center

    McKee, Lori L.; Heydon, Rachel M.

    2015-01-01

    This exploratory case study considered the opportunities for print literacy learning within multimodal ensembles that featured art, singing and digital media within the context of an intergenerational programme that brought together 13 kindergarten children (4 and 5 years) with seven elder companions. Study questions concerned how reading and…

  17. Multiscale Climate Emulator of Multimodal Wave Spectra: MUSCLE-spectra

    NASA Astrophysics Data System (ADS)

    Rueda, A.; Hegermiller, C.; Alvarez Antolinez, J. A.; Camus, P.; Vitousek, S.; Ruggiero, P.; Barnard, P.; Erikson, L. H.; Tomas, A.; Mendez, F. J.

    2016-12-01

    Characterization of multimodal directional wave spectra is important for many offshore and coastal applications, such as marine forecasting, coastal hazard assessment, and design of offshore wave energy farms and coastal structures. However, the multivariate and multiscale nature of wave climate variability makes this problem complex yet tractable using computationally-expensive numerical models. So far, the skill of statistical-downscaling models based parametric (unimodal) wave conditions is limited in large ocean basins such as the Pacific. The recent availability of long-term directional spectral data from buoys and wave hindcast models allows for development of stochastic models that include multimodal sea-state parameters. This work introduces a statistical-downscaling framework based on weather types to predict multimodal wave spectra (e.g., significant wave height, mean wave period, and mean wave direction from different storm systems, including sea and swells) from large-scale atmospheric pressure fields. For each weather type, variables of interest are modeled using the categorical distribution for the sea-state type, the Generalized Extreme Value (GEV) distribution for wave height and wave period, a multivariate Gaussian copula for the interdependence between variables, and a Markov chain model for the chronology of daily weather types. We apply the model to the Southern California coast, where local seas and swells from both the Northern and Southern Hemispheres contribute to the multimodal wave spectrum. This work allows attribution of particular extreme multimodal wave events to specific atmospheric conditions, expanding knowledge of time-dependent, climate-driven offshore and coastal sea-state conditions that have a significant influence on local nearshore processes, coastal morphology, and flood hazards.

  18. Multimodally controlled intelligent telerobot for people with disabilities

    NASA Astrophysics Data System (ADS)

    Kazi, Zunaid; Chen, Shoupu; Beitler, Matthew; Chester, Daniel; Foulds, Richard

    1996-12-01

    This paper reports on the current status of the multimodal user supervised interface and intelligent control (MUSIIC) project, which is working towards the development of an intelligent assistive telemanipulative system for people with motor disabilities. Our MUSIIC strategy overcomes the limitations of previous approaches by integrating a multimodal RUI (robot user interface) and a semi-autonomous reactive planner that will allow users with severe motor disabilities to manipulate objects in an unstructured domain. The multimodal user interface is a speech and deictic (pointing) gesture based control that guides the operation of a semi-autonomous planner controlling the assistive telerobot. MUSIIC uses a vision system to determine the three-dimensional shape, pose and color of objects and surfaces which are in the environment, and as well as an object-oriented knowledge base and planning system which superimposes information about common objects in the three-dimensional world. This approach allows the users to identify objects and tasks via a multimodal user interface which interprets their deictic gestures and a restricted natural language like speech input. The multimodal interface eliminates the need for general purpose object recognition by binding the users speech and gesture input to a locus in the domain of interest. The underlying knowledge-driven planner, combines information obtained from the user, the stereo vision mechanism as well as the knowledge bases to adapt previously learned plans to perform new tasks and also to manipulate newly introduced objects into the workspace. Therefore, what we have is a flexible and intelligent telemanipulative system that functions as an assistive robot for people with motor disabilities.

  19. The Stability of Multi-modal Traffic Network

    NASA Astrophysics Data System (ADS)

    Han, Ling-Hui; Sun, Hui-Jun; Zhu, Cheng-Juan; Wu, Jian-Jun; Jia, Bin

    2013-07-01

    There is an explicit and implicit assumption in multimodal traffic equilibrium models, that is, if the equilibrium exists, then it will also occur. The assumption is very idealized; in fact, it may be shown that the quite contrary could happen, because in multimodal traffic network, especially in mixed traffic conditions the interaction among traffic modes is asymmetric and the asymmetric interaction may result in the instability of traffic system. In this paper, to study the stability of multimodal traffic system, we respectively present the travel cost function in mixed traffic conditions and in traffic network with dedicated bus lanes. Based on a day-to-day dynamical model, we study the evolution of daily route choice of travelers in multimodal traffic network using 10000 random initial values for different cases. From the results of simulation, it can be concluded that the asymmetric interaction between the cars and buses in mixed traffic conditions can lead the traffic system to instability when traffic demand is larger. We also study the effect of travelers' perception error on the stability of multimodal traffic network. Although the larger perception error can alleviate the effect of interaction between cars and buses and improve the stability of traffic system in mixed traffic conditions, the traffic system also become instable when the traffic demand is larger than a number. For all cases simulated in this study, with the same parameters, traffic system with dedicated bus lane has better stability for traffic demand than that in mixed traffic conditions. We also find that the network with dedicated bus lane has higher portion of travelers by bus than it of mixed traffic network. So it can be concluded that building dedicated bus lane can improve the stability of traffic system and attract more travelers to choose bus reducing the traffic congestion.

  20. Multimodality Monitoring, Inflammation, and Neuroregeneration in Subarachnoid Hemorrhage

    PubMed Central

    Nogueira, Ariel B.; Esteves Veiga, José C.; Teixeira, Manoel J.

    2014-01-01

    BACKGROUND: Stroke, including subarachnoid hemorrhage (SAH), is one of the leading causes of morbidity and mortality worldwide. The mortality rate of poor-grade SAH ranges from 34% to 52%. In an attempt to improve SAH outcomes, clinical research on multimodality monitoring has been performed, as has basic science research on inflammation and neuroregeneration (which can occur due to injury-induced neurogenesis). Nevertheless, the current literature does not focus on the integrated study of these fields. Multimodality monitoring corresponds to physiological data obtained during clinical management by both noninvasive and invasive methods. Regarding inflammation and neuroregeneration, evidence suggests that, in all types of stroke, a proinflammatory phase and an anti-inflammatory phase occur consecutively; these phases affect neurogenesis, which is also influenced by other pathophysiological features of stroke, such as ischemia, seizures, and spreading depression. OBJECTIVE: To assess whether injury-induced neurogenesis is a prognostic factor in poor-grade SAH that can be monitored and modulated. METHODS: We propose a protocol for multimodality monitoring-guided hypothermia in poor-grade SAH in which cellular and molecular markers of inflammation and neuroregeneration can be monitored in parallel with clinical and multimodal data. EXPECTED OUTCOMES: This study may reveal correlations between markers of inflammation and neurogenesis in blood and cerebrospinal fluid, based on clinical and multimodality monitoring parameters. DISCUSSION: This protocol has the potential to lead to new therapies for acute, diffuse, and severe brain diseases. ABBREVIATIONS: BBB, blood-brain barrier CPP, cerebral perfusion pressure EEG, electroencephalography ICP, intracranial pressure IL, interleukin MCA, middle cerebral artery SAH, subarachnoid hemorrhage SD, spreading depression SGZ, subgranular zone SVZ, subventricular zone TCD, transcranial Doppler PMID:25050583

  1. Multimodal optimization using a bi-objective evolutionary algorithm.

    PubMed

    Deb, Kalyanmoy; Saha, Amit

    2012-01-01

    In a multimodal optimization task, the main purpose is to find multiple optimal solutions (global and local), so that the user can have better knowledge about different optimal solutions in the search space and as and when needed, the current solution may be switched to another suitable optimum solution. To this end, evolutionary optimization algorithms (EA) stand as viable methodologies mainly due to their ability to find and capture multiple solutions within a population in a single simulation run. With the preselection method suggested in 1970, there has been a steady suggestion of new algorithms. Most of these methodologies employed a niching scheme in an existing single-objective evolutionary algorithm framework so that similar solutions in a population are deemphasized in order to focus and maintain multiple distant yet near-optimal solutions. In this paper, we use a completely different strategy in which the single-objective multimodal optimization problem is converted into a suitable bi-objective optimization problem so that all optimal solutions become members of the resulting weak Pareto-optimal set. With the modified definitions of domination and different formulations of an artificially created additional objective function, we present successful results on problems with as large as 500 optima. Most past multimodal EA studies considered problems having only a few variables. In this paper, we have solved up to 16-variable test problems having as many as 48 optimal solutions and for the first time suggested multimodal constrained test problems which are scalable in terms of number of optima, constraints, and variables. The concept of using bi-objective optimization for solving single-objective multimodal optimization problems seems novel and interesting, and more importantly opens up further avenues for research and application.

  2. Systemic multimodal approach to speech therapy treatment in autistic children.

    PubMed

    Tamas, Daniela; Marković, Slavica; Milankov, Vesela

    2013-01-01

    Conditions in which speech therapy treatment is applied in autistic children are often not in accordance with characteristics of opinions and learning of people with autism. A systemic multimodal approach means motivating autistic people to develop their language speech skill through the procedure which allows reliving of their personal experience according to the contents that are presented in the their natural social environment. This research was aimed at evaluating the efficiency of speech treatment based on the systemic multimodal approach to the work with autistic children. The study sample consisted of 34 children, aged from 8 to 16 years, diagnosed to have different autistic disorders, whose results showed a moderate and severe clinical picture of autism on the Childhood Autism Rating Scale. The applied instruments for the evaluation of ability were the Childhood Autism Rating Scale and Ganzberg II test. The study subjects were divided into two groups according to the type of treatment: children who were covered by the continuing treatment and systemic multimodal approach in the treatment, and children who were covered by classical speech treatment. It is shown that the systemic multimodal approach in teaching autistic children affects the stimulation of communication, socialization, self-service and work as well as that the progress achieved in these areas of functioning was retainable after long time, too. By applying the systemic multimodal approach when dealing with autistic children and by comparing their achievements on tests applied before, during and after the application of this mode, it has been concluded that certain improvement has been achieved in the functionality within the diagnosed category. The results point to a possible direction in the creation of new methods, plans and programs in dealing with autistic children based on empirical and interactive learning.

  3. Multiscale climate emulator of multimodal wave spectra: MUSCLE-spectra

    NASA Astrophysics Data System (ADS)

    Rueda, Ana; Hegermiller, Christie A.; Antolinez, Jose A. A.; Camus, Paula; Vitousek, Sean; Ruggiero, Peter; Barnard, Patrick L.; Erikson, Li H.; Tomás, Antonio; Mendez, Fernando J.

    2017-02-01

    Characterization of multimodal directional wave spectra is important for many offshore and coastal applications, such as marine forecasting, coastal hazard assessment, and design of offshore wave energy farms and coastal structures. However, the multivariate and multiscale nature of wave climate variability makes this complex problem tractable using computationally expensive numerical models. So far, the skill of statistical-downscaling model-based parametric (unimodal) wave conditions is limited in large ocean basins such as the Pacific. The recent availability of long-term directional spectral data from buoys and wave hindcast models allows for development of stochastic models that include multimodal sea-state parameters. This work introduces a statistical downscaling framework based on weather types to predict multimodal wave spectra (e.g., significant wave height, mean wave period, and mean wave direction from different storm systems, including sea and swells) from large-scale atmospheric pressure fields. For each weather type, variables of interest are modeled using the categorical distribution for the sea-state type, the Generalized Extreme Value (GEV) distribution for wave height and wave period, a multivariate Gaussian copula for the interdependence between variables, and a Markov chain model for the chronology of daily weather types. We apply the model to the southern California coast, where local seas and swells from both the Northern and Southern Hemispheres contribute to the multimodal wave spectrum. This work allows attribution of particular extreme multimodal wave events to specific atmospheric conditions, expanding knowledge of time-dependent, climate-driven offshore and coastal sea-state conditions that have a significant influence on local nearshore processes, coastal morphology, and flood hazards.

  4. Toward investigation of Brillouin scattering in multimode polymer and silica optical fibers

    NASA Astrophysics Data System (ADS)

    Wosniok, Aleksander; Schreier, Andy

    2017-05-01

    In this paper, we present a study aimed at characterizing the optimal fiber optic components for Brillouin sensing in multimode fibers. For this purpose the use of single-mode and multimode circulators as well as couplers typically used in the Brillouin measurement setups was investigated. On the one hand the undesired coupling losses between conventional fiber optic measurement system components and a multimode sensor fiber can be overcome by replacing the singlemode components with their own multimode equivalents. On the other hand the use of multimode fiber optic circulators and multimode couplers affects the mode distribution of laser light which can impair the measurement signal backscattered in the multimode sensor fibers. In view of an increasing interest in high strain measurements using polymer optical fibers (POFs) as Brillouin-distributed sensors the investigation on Brillouin scattering effects in multimode fibers (MMFs) was performed on a low-loss perfluorinated graded-index polymer optical fiber (PFGI-POF). The obtained results were compared with those of a standard graded-index multimode (GI-MMF) silica glass optical fiber (GOF). This study confirms the relevance of the adaptation of the measurement system components to the use of the multimode sensor fibers. In addition, due to mode coupling effects occurring in the tested POF itself, the results show differences in the yield of the components adaptation in the sensory implementation of the two kinds of the tested optical fibers.

  5. Real-time resilient focusing through a bending multimode fiber.

    PubMed

    Caravaca-Aguirre, Antonio M; Niv, Eyal; Conkey, Donald B; Piestun, Rafael

    2013-05-20

    Multimode optical fibers are attractive for biomedical and sensing applications because they possess a small cross section and can bend over small radii of curvature. However, mode phase-velocity dispersion and random mode coupling change with bending, temperature, and other perturbations, producing scrambling interference among propagating modes; hence preventing its use for focusing or imaging. To tackle this problem we introduce a system capable of re-focusing light through a multimode fiber in 37ms, one order of magnitude faster than demonstrated in previous reports. As a result, the focus spot can be maintained during significant bending of the fiber, opening numerous opportunities for endoscopic imaging and energy delivery applications. We measure the transmission matrix of the fiber by projecting binary-amplitude computer generated holograms using a digital micro-mirror device controlled by a field programmable gate array. The system shows two orders of magnitude enhancements of the focus spot relative to the background.

  6. Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging

    PubMed Central

    Kuijten, Maayke M. P.; Hannah Degeling, M.; Chen, John W.; Wojtkiewicz, Gregory; Waterman, Peter; Weissleder, Ralph; Azzi, Jamil; Nicolay, Klaas; Tannous, Bakhos A.

    2015-01-01

    Liposomes are spherical, self-closed structures formed by lipid bilayers that can encapsulate drugs and/or imaging agents in their hydrophilic core or within their membrane moiety, making them suitable delivery vehicles. We have synthesized a new liposome containing gadolinium-DOTA lipid bilayer, as a targeting multimodal molecular imaging agent for magnetic resonance and optical imaging. We showed that this liposome has a much higher molar relaxivities r1 and r2 compared to a more conventional liposome containing gadolinium-DTPA-BSA lipid. By incorporating both gadolinium and rhodamine in the lipid bilayer as well as biotin on its surface, we used this agent for multimodal imaging and targeting of tumors through the strong biotin-streptavidin interaction. Since this new liposome is thermosensitive, it can be used for ultrasound-mediated drug delivery at specific sites, such as tumors, and can be guided by magnetic resonance imaging. PMID:26610702

  7. Neural Network-Based Multimode Fiber-Optic Information Transmission

    NASA Astrophysics Data System (ADS)

    Marusarz, Ronald K.; Sayeh, Mohammad R.

    2001-01-01

    A new technique for transmitting information through multimode fiber-optic cables is presented. This technique sends parallel channels through the fiber-optic cable, thereby greatly improving the data transmission rate compared with that of the current technology, which uses serial data transmission through single-mode fiber. An artificial neural network is employed to decipher the transmitted information from the received speckle pattern. Several different preprocessing algorithms are developed, tested, and evaluated. These algorithms employ average region intensity, distributed individual pixel intensity, and maximum mean-square-difference optimal group selection methods. The effect of modal dispersion on the data rate is analyzed. An increased data transmission rate by a factor of 37 over that of single-mode fibers is realized. When implementing our technique, we can increase the channel capacity of a typical multimode fiber by a factor of 6.

  8. Multimodal science teachers' discourse in modeling the water cycle

    NASA Astrophysics Data System (ADS)

    Márquez, Conxita; Izquierdo, Mercè; Espinet, Mariona

    2006-03-01

    The paper presents an intensive study of a micro-event aiming at the characterization of teacher's discourse from a multimodal communication perspective in a secondary school science classroom dealing with the topic of water cycle. The research addresses the following questions: (a) What communicative modes are used by the teacher?, (b) what role do the different communicative modes play within teacher's discourse?, and (c) what are the relationships among communicative modes being used by the teacher? Theoretical framework is developed based on three strands: multimodal communication, science teaching and learning as modeling, and social semotics and Halliday's functional grammar. An analytic scheme guiding teachers' discourse analysis is presented and results discussed. Implications for science teacher education are drawn that would contribute to the improvement of science teacher education.

  9. Recent advances in molecular, multimodal and theranostic ultrasound imaging.

    PubMed

    Kiessling, Fabian; Fokong, Stanley; Bzyl, Jessica; Lederle, Wiltrud; Palmowski, Moritz; Lammers, Twan

    2014-06-01

    Ultrasound (US) imaging is an exquisite tool for the non-invasive and real-time diagnosis of many different diseases. In this context, US contrast agents can improve lesion delineation, characterization and therapy response evaluation. US contrast agents are usually micrometer-sized gas bubbles, stabilized with soft or hard shells. By conjugating antibodies to the microbubble (MB) surface, and by incorporating diagnostic agents, drugs or nucleic acids into or onto the MB shell, molecular, multimodal and theranostic MBs can be generated. We here summarize recent advances in molecular, multimodal and theranostic US imaging, and introduce concepts how such advanced MB can be generated, applied and imaged. Examples are given for their use to image and treat oncological, cardiovascular and neurological diseases. Furthermore, we discuss for which therapeutic entities incorporation into (or conjugation to) MB is meaningful, and how US-mediated MB destruction can increase their extravasation, penetration, internalization and efficacy.

  10. The problem of multimodal concurrent serial order in behavior.

    PubMed

    Kolodny, Oren; Edelman, Shimon

    2015-09-01

    The "problem of serial order in behavior," as formulated and discussed by Lashley (1951), is arguably more pervasive and more profound both than originally stated and than currently appreciated. We spell out two complementary aspects of what we term the generalized problem of behavior: (i) multimodality, stemming from the disparate nature of the sensorimotor variables and processes that underlie behavior, and (ii) concurrency, which reflects the parallel unfolding in time of these processes and of their asynchronous interactions. We illustrate these on a number of examples, with a special focus on language, briefly survey the computational approaches to multimodal concurrency, offer some hypotheses regarding the manner in which brains address it, and discuss some of the broader implications of these as yet unresolved issues for cognitive science.

  11. Using multimodal mining to drive clinical guidelines development.

    PubMed

    Pasche, Emilie; Gobeill, Julien; Teodoro, Douglas; Vishnyakova, Dina; Gaudinat, Arnaud; Ruch, Patrick; Lovis, Christian

    2011-01-01

    We present exploratory investigations of multimodal mining to help designing clinical guidelines for antibiotherapy. Our approach is based on the assumption that combining various sources of data, such as the literature, a clinical datawarehouse, as well as information regarding costs will result in better recommendations. Compared to our baseline recommendation system based on a question-answering engine built on top of PubMed, an improvement of +16% is observed when clinical data (i.e. resistance profiles) are injected into the model. In complement to PubMed, an alternative search strategy is reported, which is significantly improved by the use of the combined multimodal approach. These results suggest that combining literature-based discovery with structured data mining can significantly improve effectiveness of decision-support systems for authors of clinical practice guidelines.

  12. Research of the multimodal brain-tumor segmentation algorithm

    NASA Astrophysics Data System (ADS)

    Lu, Yisu; Chen, Wufan

    2015-12-01

    It is well-known that the number of clusters is one of the most important parameters for automatic segmentation. However, it is difficult to define owing to the high diversity in appearance of tumor tissue among different patients and the ambiguous boundaries of lesions. In this study, a nonparametric mixture of Dirichlet process (MDP) model is applied to segment the tumor images, and the MDP segmentation can be performed without the initialization of the number of clusters. A new nonparametric segmentation algorithm combined with anisotropic diffusion and a Markov random field (MRF) smooth constraint is proposed in this study. Besides the segmentation of single modal brain tumor images, we developed the algorithm to segment multimodal brain tumor images by the magnetic resonance (MR) multimodal features and obtain the active tumor and edema in the same time. The proposed algorithm is evaluated and compared with other approaches. The accuracy and computation time of our algorithm demonstrates very impressive performance.

  13. A bioinspired multi-modal flying and walking robot.

    PubMed

    Daler, Ludovic; Mintchev, Stefano; Stefanini, Cesare; Floreano, Dario

    2015-01-19

    With the aim to extend the versatility and adaptability of robots in complex environments, a novel multi-modal flying and walking robot is presented. The robot consists of a flying wing with adaptive morphology that can perform both long distance flight and walking in cluttered environments for local exploration. The robot's design is inspired by the common vampire bat Desmodus rotundus, which can perform aerial and terrestrial locomotion with limited trade-offs. Wings' adaptive morphology allows the robot to modify the shape of its body in order to increase its efficiency during terrestrial locomotion. Furthermore, aerial and terrestrial capabilities are powered by a single locomotor apparatus, therefore it reduces the total complexity and weight of this multi-modal robot.

  14. Two-photon quantum walk in a multimode fiber

    PubMed Central

    Defienne, Hugo; Barbieri, Marco; Walmsley, Ian A.; Smith, Brian J.; Gigan, Sylvain

    2016-01-01

    Multiphoton propagation in connected structures—a quantum walk—offers the potential of simulating complex physical systems and provides a route to universal quantum computation. Increasing the complexity of quantum photonic networks where the walk occurs is essential for many applications. We implement a quantum walk of indistinguishable photon pairs in a multimode fiber supporting 380 modes. Using wavefront shaping, we control the propagation of the two-photon state through the fiber in which all modes are coupled. Excitation of arbitrary output modes of the system is realized by controlling classical and quantum interferences. This report demonstrates a highly multimode platform for multiphoton interference experiments and provides a powerful method to program a general high-dimensional multiport optical circuit. This work paves the way for the next generation of photonic devices for quantum simulation, computing, and communication. PMID:27152325

  15. Angular momentum effects in multimodal fission of {sup 226}Th

    SciTech Connect

    Chubarian, G.G.; Hurst, B.J.; OKelly, D.; Schmitt, R.P.; Itkis, M.G.; Kondratiev, N.A.; Kozulin, E.M.; Oganessian, Y.T.; Pashkevich, V.V.; Pokrovsky, I.V.; Salamatin, V.S.; Rusanov, A.Y.; Calabretta, L.; Maiolino, C.; Lukashin, K.; Agodi, C.; Bellia, G.; Hanappe, F.; Liatard, E.; Huck, A.; Stuttge, L.

    1998-12-01

    The {gamma}-rays from the multimodal fission of the {sup 226}Th formed in {sup 18}O+{sup 208}Pb was investigated at the near- and sub-barrier energies. The corresponding excitation energies at the saddle point, E{sub sp}{sup {asterisk}}, ranged from 23 to 26 MeV. The average {gamma}-ray multiplicities and relative {gamma}-ray energies as a function of the mass of the fission fragments exhibits a complex structure and strong variations. Such strong variations have never been previously observed in heavy ion-induced fusion-fission reactions. Obtained results may be explained with the influence of shell effects on the properties of the fission fragments. Present work is the one in series of investigation of the multimodal fission phenomena in At-Th region. {copyright} {ital 1998 American Institute of Physics.}

  16. Modification of species-based differential evolution for multimodal optimization

    NASA Astrophysics Data System (ADS)

    Idrus, Said Iskandar Al; Syahputra, Hermawan; Firdaus, Muliawan

    2015-12-01

    At this time optimization has an important role in various fields as well as between other operational research, industry, finance and management. Optimization problem is the problem of maximizing or minimizing a function of one variable or many variables, which include unimodal and multimodal functions. Differential Evolution (DE), is a random search technique using vectors as an alternative solution in the search for the optimum. To localize all local maximum and minimum on multimodal function, this function can be divided into several domain of fitness using niching method. Species-based niching method is one of method that build sub-populations or species in the domain functions. This paper describes the modification of species-based previously to reduce the computational complexity and run more efficiently. The results of the test functions show species-based modifications able to locate all the local optima in once run the program.

  17. MULTIMODALITY IMAGING: BEYOND PET/CT AND SPECT/CT

    PubMed Central

    Cherry, Simon R.

    2009-01-01

    Multimodality imaging with PET/CT and SPECT/CT has become commonplace in clinical practice and in preclinical and basic medical research. Do other combinations of imaging modalities have a similar potential to impact medical science and clinical medicine? The combination of PET or SPECT with MRI is an area of active research at the present time, while other, perhaps less obvious combinations, including CT/MR and PET/optical also are being studied. In addition to the integration of the instrumentation, there are parallel developments in synthesizing imaging agents that can be viewed by multiple imaging modalities. Is the fusion of PET and SPECT with CT the ultimate answer in multimodality imaging, or is it just the first example of a more general trend towards harnessing the complementary nature of the different modalities on integrated imaging platforms? PMID:19646559

  18. Mode Launcher Design for the Multi-moded DLDS

    SciTech Connect

    Li, Zenghai

    2003-04-30

    The DLDS (Delay Line Distribution System) power delivery system proposed by KEK combines several klystrons to obtain the high peak power required to drive a TeV scale linear collider. In this system the combined klystron output is subdivided into shorter pulses by proper phasing of the sources, and each subpulse is delivered to various accelerator sections via separate waveguides. A cost-saving improvement suggested by SLAC is to use a single multimoded waveguide to deliver the power of all the subpulses. This scheme requires a mode launcher that can deliver each subpulse by way of a different waveguide mode through selective phasing of the sources when combining their power. We present a compact design for such a mode launcher that converts the power from four rectangular waveguide feeds to separate modes in a multi-moded circular guide through coupling slots. Such a design has been simulated and found to satisfy the requirements for high efficiency and low surface fields.

  19. Vestibular system: the many facets of a multimodal sense.

    PubMed

    Angelaki, Dora E; Cullen, Kathleen E

    2008-01-01

    Elegant sensory structures in the inner ear have evolved to measure head motion. These vestibular receptors consist of highly conserved semicircular canals and otolith organs. Unlike other senses, vestibular information in the central nervous system becomes immediately multisensory and multimodal. There is no overt, readily recognizable conscious sensation from these organs, yet vestibular signals contribute to a surprising range of brain functions, from the most automatic reflexes to spatial perception and motor coordination. Critical to these diverse, multimodal functions are multiple computationally intriguing levels of processing. For example, the need for multisensory integration necessitates vestibular representations in multiple reference frames. Proprioceptive-vestibular interactions, coupled with corollary discharge of a motor plan, allow the brain to distinguish actively generated from passive head movements. Finally, nonlinear interactions between otolith and canal signals allow the vestibular system to function as an inertial sensor and contribute critically to both navigation and spatial orientation.

  20. Combining Multi-modal Features for Social Media Analysis

    NASA Astrophysics Data System (ADS)

    Nikolopoulos, Spiros; Giannakidou, Eirini; Kompatsiaris, Ioannis; Patras, Ioannis; Vakali, Athena

    In this chapter we discuss methods for efficiently modeling the diverse information carried by social media. The problem is viewed as a multi-modal analysis process where specialized techniques are used to overcome the obstacles arising from the heterogeneity of data. Focusing at the optimal combination of low-level features (i.e., early fusion), we present a bio-inspired algorithm for feature selection that weights the features based on their appropriateness to represent a resource. Under the same objective of optimal feature combination we also examine the use of pLSA-based aspect models, as the means to define a latent semantic space where heterogeneous types of information can be effectively combined. Tagged images taken from social sites have been used in the characteristic scenarios of image clustering and retrieval, to demonstrate the benefits of multi-modal analysis in social media.

  1. Raman Plus X: Biomedical Applications of Multimodal Raman Spectroscopy

    PubMed Central

    Das, Nandan K.; Dai, Yichuan; Liu, Peng; Hu, Chuanzhen; Tong, Lieshu; Chen, Xiaoya

    2017-01-01

    Raman spectroscopy is a label-free method of obtaining detailed chemical information about samples. Its compatibility with living tissue makes it an attractive choice for biomedical analysis, yet its translation from a research tool to a clinical tool has been slow, hampered by fundamental Raman scattering issues such as long integration times and limited penetration depth. In this review we detail the how combining Raman spectroscopy with other techniques yields multimodal instruments that can help to surmount the translational barriers faced by Raman alone. We review Raman combined with several optical and non-optical methods, including fluorescence, elastic scattering, OCT, phase imaging, and mass spectrometry. In each section we highlight the power of each combination along with a brief history and presentation of representative results. Finally, we conclude with a perspective detailing both benefits and challenges for multimodal Raman measurements, and give thoughts on future directions in the field. PMID:28686212

  2. Creating Tangible Interfaces by Augmenting Physical Objects with Multimodal Language

    SciTech Connect

    McGee, David R. ); Cohen, Philip R.

    2001-01-01

    Rasa is a tangible augmented reality environment that digitally enhances the existing paper-based command and control capability in a military command post. By observing and understanding the users' speech, pen, and touch-based multimodal language, Rasa computationally augments the physical objects on a command post map, linking these items to digital representations of the same; for example, linking a paper map to the world and Post-it notes to military units. Herein, we give a thorough account of Rasa's underlying multiagent framework, and its recognition, understanding, and multimodal integration components. Moreover, we examine five properties of language: generativity, comprehensibility, compositionality, referentiality, and, at times, persistence--that render it suitable as an augmentation approach, contrasting these properties to those of other augmentation methods. It is these properties of language that allow users of Rasa to augment physical objects, transforming them into tangible interfaces.

  3. A biconical taper multi-mode fiber SERS sensor

    NASA Astrophysics Data System (ADS)

    Bai, Hua; Chen, Zhenyi; Chen, Na; Guo, Qiang; Zhang, Kun; Pang, Fufei; Wang, Tingyun

    2010-12-01

    A surface-enhanced Raman scattering (SERS) optical fiber sensor using biconical taper multi-mode fiber (MMF) is proposed. It is fabricated by fused elongating a multi-mode fiber and then coated the silver colloid on its waist. The main advantage of this sensor is that it can increase the SERS active substrate region to make more molecules be excited to produce Raman signal. Silver colloid is selected as the active substrate of SERS. A modified immobilizing process is introduced to increase the thickness of the immobilized layer and reduce the preparation time. Various concentration of R6G is used to detect the performance of the sensor. Strong Raman signal is detected from the waist of the tapered fiber. The detection sensitivity is up to 10-9M.

  4. Numerical modelling of multimode fibre-optic communication lines

    SciTech Connect

    Sidelnikov, O S; Fedoruk, M P; Sygletos, S; Ferreira, F

    2016-01-31

    The results of numerical modelling of nonlinear propagation of an optical signal in multimode fibres with a small differential group delay are presented. It is found that the dependence of the error vector magnitude (EVM) on the differential group delay can be reduced by increasing the number of ADC samples per symbol in the numerical implementation of the differential group delay compensation algorithm in the receiver. The possibility of using multimode fibres with a small differential group delay for data transmission in modern digital communication systems is demonstrated. It is shown that with increasing number of modes the strong coupling regime provides a lower EVM level than the weak coupling one. (fibre-optic communication lines)

  5. Multi-modal image registration using structural features.

    PubMed

    Kasiri, Keyvan; Clausi, David A; Fieguth, Paul

    2014-01-01

    Multi-modal image registration has been a challenging task in medical images because of the complex intensity relationship between images to be aligned. Registration methods often rely on the statistical intensity relationship between the images which suffers from problems such as statistical insufficiency. The proposed registration method works based on extracting structural features by utilizing the complex phase and gradient-based information. By employing structural relationships between different modalities instead of complex similarity measures, the multi-modal registration problem is converted into a mono-modal one. Therefore, conventional mono-modal similarity measures can be utilized to evaluate the registration results. This new registration paradigm has been tested on magnetic resonance (MR) brain images of different modes. The method has been evaluated based on target registration error (TRE) to determine alignment accuracy. Quantitative results demonstrate that the proposed method is capable of achieving comparable registration accuracy compared to the conventional mutual information.

  6. Raman Plus X: Biomedical Applications of Multimodal Raman Spectroscopy.

    PubMed

    Das, Nandan K; Dai, Yichuan; Liu, Peng; Hu, Chuanzhen; Tong, Lieshu; Chen, Xiaoya; Smith, Zachary J

    2017-07-07

    Raman spectroscopy is a label-free method of obtaining detailed chemical information about samples. Its compatibility with living tissue makes it an attractive choice for biomedical analysis, yet its translation from a research tool to a clinical tool has been slow, hampered by fundamental Raman scattering issues such as long integration times and limited penetration depth. In this review we detail the how combining Raman spectroscopy with other techniques yields multimodal instruments that can help to surmount the translational barriers faced by Raman alone. We review Raman combined with several optical and non-optical methods, including fluorescence, elastic scattering, OCT, phase imaging, and mass spectrometry. In each section we highlight the power of each combination along with a brief history and presentation of representative results. Finally, we conclude with a perspective detailing both benefits and challenges for multimodal Raman measurements, and give thoughts on future directions in the field.

  7. Multimode laser emission from dye doped polymer optical fiber.

    PubMed

    Sheeba, Mavila; Thomas, Kannampuzha J; Rajesh, Mandamparambil; Nampoori, Vadakkedathu P N; Vallabhan, Chakkalakkal P G; Radhakrishnan, Padmanabhan

    2007-11-20

    Multimode laser emission is observed in a polymer optical fiber doped with a mixture of Rhodamine 6G (Rh 6G) and Rhodamine B (Rh B) dyes. Tuning of laser emission is achieved by using the mixture of dyes due to the energy transfer occurring from donor molecule (Rh 6G) to acceptor molecule (Rh B). The dye doped poly(methyl methacrylate)-based polymer optical fiber is pumped axially at one end of the fiber using a 532 nm pulsed laser beam from a Nd:YAG laser and the fluorescence emission is collected from the other end. At low pump energy levels, fluorescence emission is observed. When the energy is increased beyond a threshold value, laser emission occurs with a multimode structure. The optical feedback for the gain medium is provided by the cylindrical surface of the optical fiber, which acts as a cavity. This fact is confirmed by the mode spacing dependence on the diameter of the fiber.

  8. Melanoma detection using smartphone and multimode hyperspectral imaging

    NASA Astrophysics Data System (ADS)

    MacKinnon, Nicholas; Vasefi, Fartash; Booth, Nicholas; Farkas, Daniel L.

    2016-04-01

    This project's goal is to determine how to effectively implement a technology continuum from a low cost, remotely deployable imaging device to a more sophisticated multimode imaging system within a standard clinical practice. In this work a smartphone is used in conjunction with an optical attachment to capture cross-polarized and collinear color images of a nevus that are analyzed to quantify chromophore distribution. The nevus is also imaged by a multimode hyperspectral system, our proprietary SkinSpect™ device. Relative accuracy and biological plausibility of the two systems algorithms are compared to assess aspects of feasibility of in-home or primary care practitioner smartphone screening prior to rigorous clinical analysis via the SkinSpect.

  9. [Multimodal neuromonitoring for the critical care management of acute coma].

    PubMed

    Ltaief, Z; Ben-Hamouda, N; Suys, T; Daniel, R T; Rossetti, A O; Oddo, M

    2014-12-10

    Management of neurocritical care patients is focused on the prevention and treatment of secondary brain injury, i.e. the number of pathophysiological intracerebral (edema, ischemia, energy dysfunction, seizures) and systemic (hyperthermia, disorders of glucose homeostasis) events that occur following the initial insult (stroke, hemorrhage, head trauma, brain anoxia) that may aggravate patient outcome. The current therapeutic paradigm is based on multimodal neuromonitoring, including invasive (intracranial pressure, brain oxygen, cerebral microdialysis) and non-invasive (transcranial doppler, near-infrared spectroscopy, EEG) tools that allows targeted individualized management of acute coma in the early phase. The aim of this review is to describe the utility of multimodal neuromonitoring for the critical care management of acute coma.

  10. The multimodal approach to the treatment of minor depression.

    PubMed

    Lazarus, A A

    1992-01-01

    The multimodal approach endeavors to achieve rapid remission of depressive symptoms and significant relapse prevention. It is predicated on the assumption that it is usually insufficient to facilitate the acquisition of insight, dispute irrational ideas, and change negative automatic thoughts. In addition to the foregoing, behavioral deficits, sensory overloads, and negative imagery must be identified and remedied, and antidepressant medication should be considered. This paper outlines a seven-pronged approach in the treatment of "minor" depression. Some of the procedures include: assertiveness training, a "sensate focus" of enjoyable events, coping imagery, time projection, cognitive disputation, role-playing, desensitization, family therapy, and biological prophylaxis. In essence, this broad-based approach recommends that attention be paid not only to cognitive issues, but also to specific behaviors, sensations, images, interpersonal relationships, and other interactive effects. The multimodal framework (BASIC I.D.) enables the practitioner to administer the necessary measures in a systematic and comprehensive manner.

  11. Multimode resonant Auger scattering from the ethene molecule.

    PubMed

    Liu, Ji-Cai; Nicolas, Christophe; Sun, Yu-Ping; Flammini, Roberto; O'Keeffe, Patrick; Avaldi, Lorenzo; Morin, Paul; Kimberg, Victor; Kosugi, Nobuhiro; Gel'mukhanov, Faris; Miron, Catalin

    2011-05-12

    Resonant Auger spectra of ethene molecule have been measured with vibrational resolution at several excitation energies in the region of the C1s(-1)1b(2g)(π*) resonance. The main features observed in the experiment have been assigned and are accurately interpreted on the basis of ab initio multimode calculations. Theory explains the extended vibrational distribution of the resonant Auger spectra and its evolution as a function of the excitation energy by multimode excitation during the scattering process. As a result, the resonant Auger spectra display two qualitatively different spectral features following the Raman and non-Raman dispersion laws, respectively. Calculations show that two observed thresholds of formation of non-Raman spectral bands are related to the "double-edge" structure of the X-ray absorption spectrum.

  12. Multimodal targeted high relaxivity thermosensitive liposome for in vivo imaging

    NASA Astrophysics Data System (ADS)

    Kuijten, Maayke M. P.; Hannah Degeling, M.; Chen, John W.; Wojtkiewicz, Gregory; Waterman, Peter; Weissleder, Ralph; Azzi, Jamil; Nicolay, Klaas; Tannous, Bakhos A.

    2015-11-01

    Liposomes are spherical, self-closed structures formed by lipid bilayers that can encapsulate drugs and/or imaging agents in their hydrophilic core or within their membrane moiety, making them suitable delivery vehicles. We have synthesized a new liposome containing gadolinium-DOTA lipid bilayer, as a targeting multimodal molecular imaging agent for magnetic resonance and optical imaging. We showed that this liposome has a much higher molar relaxivities r1 and r2 compared to a more conventional liposome containing gadolinium-DTPA-BSA lipid. By incorporating both gadolinium and rhodamine in the lipid bilayer as well as biotin on its surface, we used this agent for multimodal imaging and targeting of tumors through the strong biotin-streptavidin interaction. Since this new liposome is thermosensitive, it can be used for ultrasound-mediated drug delivery at specific sites, such as tumors, and can be guided by magnetic resonance imaging.

  13. Management of pediatric hepatocellular carcinoma: A multimodal approach.

    PubMed

    Kohorst, Mira A; Warad, Deepti M; Matsumoto, Jane M; Heimbach, Julie K; El-Youssef, Mounif; Arndt, Carola A S; Rodriguez, Vilmarie; Nageswara Rao, Amulya A

    2017-09-01

    HCC is rare in the pediatric population, but is the second most common liver malignancy in children. Survival rates for primary unresectable HCC have been dismal. The objective of this study was to describe our experience with a multimodal approach for the management of unresectable HCC in two adolescent patients and to review the literature. Both patients are currently alive with no recurrence at 51 and 29 months post-transplant. Multimodality treatment involving chemotherapy with doxorubicin, cisplatin, and sorafenib; TACE; timely liver transplantation; and post-transplant therapy with sorafenib and mTOR inhibitors may help improve outcomes and prolong survival in pediatric patients with unresectable HCC. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Multimodal optical molecular image reconstruction with frequency domain measurements.

    PubMed

    Bartels, M; Chen, W; Bardhan, R; Ke, S; Halas, N J; Wareing, T; McGhee, J; Joshi, A

    2009-01-01

    Multimodality molecular imaging is becoming more and more important to understand both the structural and the functional characteristics of tissue, organs and tumors. So far, invasive nuclear methods utilizing ionizing radiation have been the "gold standard" of molecular imaging. We investigate non-contact, non-invasive, patient-tolerant and inexpensive near infrared (NIR) frequency domain optical tomography (FDOT) as a functional complement to structural X-ray computed tomography (CT) data. We show a novel multifrequency NIR FDOT approach both in transmission and reflectance mode and employ radiative transport equation (RTE) for 3D reconstruction of a target with novel fluorescent gold nanoshell indocyanine green (NS ICG) in an ex vivo nude mouse. The results demonstrate that gold NS ICG with multifrequency NIR FDOT is a promising fluorophore for multimodal optical molecular image reconstruction.

  15. Recent Advances in Molecular, Multimodal and Theranostic Ultrasound Imaging

    PubMed Central

    Kiessling, Fabian; Fokong, Stanley; Bzyl, Jessica; Lederle, Wiltrud; Palmowski, Moritz; Lammers, Twan

    2014-01-01

    Ultrasound (US) imaging is an exquisite tool for the non-invasive and real-time diagnosis of many different diseases. In this context, US contrast agents can improve lesion delineation, characterization and therapy response evaluation. US contrast agents are usually micrometer-sized gas bubbles, stabilized with soft or hard shells. By conjugating antibodies to the microbubble (MB) surface, and by incorporating diagnostic agents, drugs or nucleic acids into or onto the MB shell, molecular, multimodal and theranostic MB can be generated. We here summarize recent advances in molecular, multimodal and theranostic US imaging, and introduce concepts how such advanced MB can be generated, applied and imaged. Examples are given for their use to image and treat oncological, cardiovascular and neurological diseases. Furthermore, we discuss for which therapeutic entities incorporation into (or conjugation to) MB is meaningful, and how US-mediated MB destruction can increase their extravasation, penetration, internalization and efficacy. PMID:24316070

  16. [Multimodal therapy concepts for failed back surgery syndrome].

    PubMed

    Casser, Hans-Raimund

    2016-09-01

    Failed back surgery syndrome (FBSS) is a frequent complication (15-40 %) of lumbar disc surgery and is rarely successfully treated by surgery with the exception of a re-prolapse associated with radicular pain. Multimodal pain treatment, however, is indicated by a lack of pathoanatomical correlates, unclear cause and psychosocial risk factors.This review describes a standardized non-operative treatment starting with broad interdisciplinary clarification by medical, psychological and physiotherapeutic means (assessment).If the conditions for multimodal pain therapy are met, the OPS 8‑918-procedure can be applied to avoid chronic developing pain. In doing so, the already issued quality standards and guidelines for documentation should be respected.

  17. Multimodal spatial calibration for accurately registering EEG sensor positions.

    PubMed

    Zhang, Jianhua; Chen, Jian; Chen, Shengyong; Xiao, Gang; Li, Xiaoli

    2014-01-01

    This paper proposes a fast and accurate calibration method to calibrate multiple multimodal sensors using a novel photogrammetry system for fast localization of EEG sensors. The EEG sensors are placed on human head and multimodal sensors are installed around the head to simultaneously obtain all EEG sensor positions. A multiple views' calibration process is implemented to obtain the transformations of multiple views. We first develop an efficient local repair algorithm to improve the depth map, and then a special calibration body is designed. Based on them, accurate and robust calibration results can be achieved. We evaluate the proposed method by corners of a chessboard calibration plate. Experimental results demonstrate that the proposed method can achieve good performance, which can be further applied to EEG source localization applications on human brain.

  18. Multimodal Spatial Calibration for Accurately Registering EEG Sensor Positions

    PubMed Central

    Chen, Shengyong; Xiao, Gang; Li, Xiaoli

    2014-01-01

    This paper proposes a fast and accurate calibration method to calibrate multiple multimodal sensors using a novel photogrammetry system for fast localization of EEG sensors. The EEG sensors are placed on human head and multimodal sensors are installed around the head to simultaneously obtain all EEG sensor positions. A multiple views' calibration process is implemented to obtain the transformations of multiple views. We first develop an efficient local repair algorithm to improve the depth map, and then a special calibration body is designed. Based on them, accurate and robust calibration results can be achieved. We evaluate the proposed method by corners of a chessboard calibration plate. Experimental results demonstrate that the proposed method can achieve good performance, which can be further applied to EEG source localization applications on human brain. PMID:24803954

  19. Two-photon quantum walk in a multimode fiber.

    PubMed

    Defienne, Hugo; Barbieri, Marco; Walmsley, Ian A; Smith, Brian J; Gigan, Sylvain

    2016-01-01

    Multiphoton propagation in connected structures-a quantum walk-offers the potential of simulating complex physical systems and provides a route to universal quantum computation. Increasing the complexity of quantum photonic networks where the walk occurs is essential for many applications. We implement a quantum walk of indistinguishable photon pairs in a multimode fiber supporting 380 modes. Using wavefront shaping, we control the propagation of the two-photon state through the fiber in which all modes are coupled. Excitation of arbitrary output modes of the system is realized by controlling classical and quantum interferences. This report demonstrates a highly multimode platform for multiphoton interference experiments and provides a powerful method to program a general high-dimensional multiport optical circuit. This work paves the way for the next generation of photonic devices for quantum simulation, computing, and communication.

  20. Multimodal Multipart Learning for Action Recognition in Depth Videos.

    PubMed

    Shahroudy, Amir; Ng, Tian-Tsong; Yang, Qingxiong; Wang, Gang

    2016-10-01

    The articulated and complex nature of human actions makes the task of action recognition difficult. One approach to handle this complexity is dividing it to the kinetics of body parts and analyzing the actions based on these partial descriptors. We propose a joint sparse regression based learning method which utilizes the structured sparsity to model each action as a combination of multimodal features from a sparse set of body parts. To represent dynamics and appearance of parts, we employ a heterogeneous set of depth and skeleton based features. The proper structure of multimodal multipart features are formulated into the learning framework via the proposed hierarchical mixed norm, to regularize the structured features of each part and to apply sparsity between them, in favor of a group feature selection. Our experimental results expose the effectiveness of the proposed learning method in which it outperforms other methods in all three tested datasets while saturating one of them by achieving perfect accuracy.

  1. Multimode nondestructive detecting method for high-speed rail defects

    NASA Astrophysics Data System (ADS)

    Sun, Mingjian; Cheng, Xingzhen; Wan, Guangnan; Liu, Ting; Fu, Ying; Wang, Yan

    2015-11-01

    It is very important to detect the surface defects of the high-speed rail for security concerns. A multimode detecting method, which integrates high resolution of optical image, high precision of photoacoustic detection and strong penetration of ultrasound detecting, is proposed for the rail defect detection. Utilizing the surface defect characteristics obtained from optical signal, the photoacoustic and ultrasound scanning region could be determined, and rail shallow and internal defect characteristics can be acquired subsequently. Eventually, fusing three modal signals mentioned above, the information of the entire rail defect, including type, extension trend and depth can be detected. It has been proved that the multimode method can improve the detecting efficiency, and enlarge the detection range in the meantime.

  2. Angular momentum effects in multimodal fission of 226Th

    NASA Astrophysics Data System (ADS)

    Chubarian, G. G.; Hurst, B. J.; O'Kelly, D.; Schmitt, R. P.; Itkis, M. G.; Kondratiev, N. A.; Kozulin, E. M.; Oganessian, Yu. Ts.; Pashkevich, V. V.; Pokrovsky, I. V.; Salamatin, V. S.; Rusanov, A. Ya.; Calabretta, L.; Maiolino, C.; Lukashin, K.; Agodi, C.; Bellia, G.; Hanappe, F.; Liatard, E.; Huck, A.; Stuttgé, L.

    1998-12-01

    The γ-rays from the multimodal fission of the 226Th formed in 18O+208Pb was investigated at the near- and sub-barrier energies. The corresponding excitation energies at the saddle point, Esp*, ranged from 23 to 26 MeV. The average γ-ray multiplicities and relative γ-ray energies as a function of the mass of the fission fragments exhibits a complex structure and strong variations. Such strong variations have never been previously observed in heavy ion-induced fusion-fission reactions. Obtained results may be explained with the influence of shell effects on the properties of the fission fragments. Present work is the one in series of investigation of the multimodal fission phenomena in At-Th region.

  3. Multimode-Guided-Wave Ultrasonic Scanning of Materials

    NASA Technical Reports Server (NTRS)

    Roth, Don

    2006-01-01

    Two documents discuss a method of characterizing advanced composite materials by use of multimode-guided ultrasonic waves. A transmitting transducer excites modulated (e.g., pulsed) ultrasonic waves at one location on a surface of a plate specimen. The waves interact with microstructure and flaws as they propagate through the specimen to a receiving transducer at a different location. The received signal is analyzed to determine the total (multimode) ultrasonic response of the specimen and utilize this response to evaluate microstructure and flaws. The analysis is performed by software that extracts parameters of signals in the time and frequency domains. Scanning is effected by using computer-controlled motorized translation stages to position the transducers at specified pairs of locations and repeating the measurement, data-acquisition, and data-analysis processes at the successive locations. One document presents results of a scan of a specimen containing a delamination.

  4. Multimode delay compensation in fibers with profile distortions.

    PubMed

    Marcuse, D

    1979-12-01

    Multimode fibers with power-law index profiles achieve maximum bandwidth for a well-defined optimum value of the exponent a of the power-law function. Even slight sinusoidal fluctuations superimposed on the ideal power-law profile reduce the signal bandwidth of the fiber dramatically. It is shown in this paper that phase reversal of the sinusoidal fluctuation at the midpoint of the fiber leads to substantial compensation of the multimode time delay dispersion. This investigation proves that sinusoidal (and of course more general) perturbations superimposed on perfect power-law index profiles lead to less severe degradation of the fiber bandwidth if their phases vary as a function of the fiber length coordinate z.

  5. Mono- and multimodal registration of optical breast images

    NASA Astrophysics Data System (ADS)

    Pearlman, Paul C.; Adams, Arthur; Elias, Sjoerd G.; Mali, Willem P. Th. M.; Viergever, Max A.; Pluim, Josien P. W.

    2012-08-01

    Optical breast imaging offers the possibility of noninvasive, low cost, and high sensitivity imaging of breast cancers. Poor spatial resolution and a lack of anatomical landmarks in optical images of the breast make interpretation difficult and motivate registration and fusion of these data with subsequent optical images and other breast imaging modalities. Methods used for registration and fusion of optical breast images are reviewed. Imaging concerns relevant to the registration problem are first highlighted, followed by a focus on both monomodal and multimodal registration of optical breast imaging. Where relevant, methods pertaining to other imaging modalities or imaged anatomies are presented. The multimodal registration discussion concerns digital x-ray mammography, ultrasound, magnetic resonance imaging, and positron emission tomography.

  6. EMS Student Handbook.

    ERIC Educational Resources Information Center

    Ogle, Patrick

    This student guide is one of a series of self-contained materials for students enrolled in an emergency medical services (EMS) training program. Discussed in the individual sections of the guide are the following topics: the purpose and history of EMS professionals; EMS training, certification and examinations (national and state certification and…

  7. Multimodal Imaging of Spike Propagation: A Technical Case Report

    PubMed Central

    Tanaka, N.; Grant, P.E.; Suzuki, N.; Madsen, J.R.; Bergin, A.M.; Hämäläinen, M.S; Stufflebeam, S.M.

    2012-01-01

    SUMMARY We report an 11-year-old boy with intractable epilepsy, who had cortical dysplasia in the right superior frontal gyrus. Spatiotemporal source analysis of MEG and EEG spikes demonstrated a similar time course of spike propagation from the superior to inferior frontal gyri, as observed on intracranial EEG. The tractography reconstructed from DTI showed a fiber connection between these areas. Our multimodal approach demonstrates spike propagation and a white matter tract guiding the propagation. PMID:21960488

  8. Multimode circuit quantum electrodynamics with hybrid metamaterial transmission lines.

    PubMed

    Egger, D J; Wilhelm, F K

    2013-10-18

    Quantum transmission lines are central to superconducting and hybrid quantum computing. In this work we show how coupling them to a left-handed transmission line allows circuit QED to reach a new regime: multimode ultrastrong coupling. Out of the many potential applications of this novel device, we discuss the preparation of multipartite entangled states and the simulation of the spin-boson model where a quantum phase transition is reached up to finite size effects.

  9. Multimode-diode-pumped gas (alkali-vapor) laser

    SciTech Connect

    Page, R H; Beach, R J; Kanz, V K

    2005-08-22

    We report the first demonstration of a multimode-diode-pumped gas laser--Rb vapor operating on the 795 nm resonance transition. Peak output of {approx}1 Watt was obtained using a volume-Bragg-grating stabilized pump diode array. The laser's output radiance exceeded the pump radiance by a factor greater than 2000. Power scaling (by pumping with larger diode arrays) is therefore possible.

  10. MINERVA - A Multi-Modal Radiation Treatment Planning System

    SciTech Connect

    D. E. Wessol; C. A. Wemple; D. W. Nigg; J. J. Cogliati; M. L. Milvich; C. Frederickson; M. Perkins; G. A. Harkin

    2004-10-01

    Recently, research efforts have begun to examine the combination of BNCT with external beam photon radiotherapy (Barth et al. 2004). In order to properly prepare treatment plans for patients being treated with combinations of radiation modalities, appropriate planning tools must be available. To facilitiate this, researchers at the Idaho National Engineering and Environmental Laboratory (INEEL)and Montana State University (MSU) have undertaken development of a fully multi-modal radiation treatment planning system.

  11. Multimodality imaging of adult gastric emergencies: A pictorial review

    PubMed Central

    Sunnapwar, Abhijit; Ojili, Vijayanadh; Katre, Rashmi; Shah, Hardik; Nagar, Arpit

    2017-01-01

    Acute gastric emergencies require urgent surgical or nonsurgical intervention because they are associated with high morbidity and mortality. Imaging plays an important role in diagnosis since the clinical symptoms are often nonspecific and radiologist may be the first one to suggest a diagnosis as the imaging findings are often characteristic. The purpose of this article is to provide a comprehensive review of multimodality imaging (plain radiograph, fluoroscopy, and computed tomography) of various life threatening gastric emergencies. PMID:28515579

  12. Bichromatic emission and multimode dynamics in bidirectional ring lasers

    SciTech Connect

    Perez-Serrano, Antonio; Javaloyes, Julien; Balle, Salvador

    2010-04-15

    The multimode dynamics of a two-level ring laser is explored numerically using a bidirectional traveling wave model retaining the spatial effects due to the presence of counter-propagating electric fields in the population inversion. Dynamical regimes where the emission in each direction occurs at different wavelengths are studied. Mode-locked unidirectional emission for large gain bandwidth and relatively small detuning is reported.

  13. Numerical aperture of multimode fibers by several methods - Resolving differences

    NASA Astrophysics Data System (ADS)

    Franzen, Douglas L.; Young, Matt; Cherin, Allen H.; Head, E. D.; Hackert, Michael J.

    1989-06-01

    An industry-wide study among members of the Electronic Industries Association was conducted to document differences among three numerical aperture measurement methods. Results on 12 multimode graded-index fibers indicate systematic differences exist among commonly used far-field and index-profile techniques. Differences can be explained by a wavelength-dependent factor and choice of definitions. Conversion factors can be used to relate the various methods.

  14. Multimodal brain monitoring reduces major neurologic complications in cardiac surgery.

    PubMed

    Zanatta, Paolo; Messerotti Benvenuti, Simone; Bosco, Enrico; Baldanzi, Fabrizio; Palomba, Daniela; Valfrè, Carlo

    2011-12-01

    Although adverse neurologic outcomes are common complications of cardiac surgery, intraoperative brain monitoring has not received adequate attention. The aim of the present study was to evaluate the effectiveness of multimodal brain monitoring in the prevention of major brain injury and reducing the duration of mechanical ventilation, intensive care unit, and postoperative hospital stays after cardiac surgery. A retrospective, observational, controlled study. A single-center regional hospital. One thousand seven hundred twenty-one patients who had undergone cardiac surgery with cardiopulmonary bypass from July 2007 to July 2010. One hundred sixty-six patients with multimodal brain monitoring and a control group without brain monitoring (N = 1,555) were compared retrospectively. Multimodal brain monitoring was performed for 166 patients, consisting of intraoperative recordings of somatosensory-evoked potentials, electroencephalography, and transcranial Doppler. The incidence of major neurologic complications and the duration of mechanical ventilation, intensive care unit, and postoperative hospital stays were considered. Patients with brain monitoring had a significantly lower incidence of perioperative major neurologic complications (0%) than those without monitoring (4.06%, p = 0.01) and required significantly shorter periods of mechanical ventilation (p = 0.001) and intensive care unit stays (p = 0.01) than controls. The length of postoperative hospital stays did not differ significantly between the 2 groups (p = 0.57). This preliminary study suggests that multimodal brain monitoring can reduce the incidence of neurologic complications as well as hospital costs associated with post-cardiac surgery patient care. Furthermore, intraoperative brain monitoring provides useful information about brain functioning, blood flow velocity, and metabolism, which may guide the anesthesiologist during surgery. Copyright © 2011 Elsevier Inc. All rights reserved.

  15. Multimodal Task-Driven Dictionary Learning for Image Classification

    DTIC Science & Technology

    2015-12-18

    36]. This is achieved by formulating it as a bilevel optimization problem [37], [38]. In particular, a stochastic gradient descent algorithm has...multimodal dictionary learning is smooth and can be solved using a stochastic 3 gradient descent algorithm. 1 • Flexible feature-level fusion: An extension of...efficient online algorithm is proposed in [19] to find the dictionary D as the minimizer of the following stochastic cost over the convex set D: g (D

  16. Construction of a multimodal CT-video chest model

    NASA Astrophysics Data System (ADS)

    Byrnes, Patrick D.; Higgins, William E.

    2014-03-01

    Bronchoscopy enables a number of minimally invasive chest procedures for diseases such as lung cancer and asthma. For example, using the bronchoscope's continuous video stream as a guide, a physician can navigate through the lung airways to examine general airway health, collect tissue samples, or administer a disease treatment. In addition, physicians can now use new image-guided intervention (IGI) systems, which draw upon both three-dimensional (3D) multi-detector computed tomography (MDCT) chest scans and bronchoscopic video, to assist with bronchoscope navigation. Unfortunately, little use is made of the acquired video stream, a potentially invaluable source of information. In addition, little effort has been made to link the bronchoscopic video stream to the detailed anatomical information given by a patient's 3D MDCT chest scan. We propose a method for constructing a multimodal CT-video model of the chest. After automatically computing a patient's 3D MDCT-based airway-tree model, the method next parses the available video data to generate a positional linkage between a sparse set of key video frames and airway path locations. Next, a fusion/mapping of the video's color mucosal information and MDCT-based endoluminal surfaces is performed. This results in the final multimodal CT-video chest model. The data structure constituting the model provides a history of those airway locations visited during bronchoscopy. It also provides for quick visual access to relevant sections of the airway wall by condensing large portions of endoscopic video into representative frames containing important structural and textural information. When examined with a set of interactive visualization tools, the resulting fused data structure provides a rich multimodal data source. We demonstrate the potential of the multimodal model with both phantom and human data.

  17. The Johns Hopkins University multimodal dataset for human action recognition

    NASA Astrophysics Data System (ADS)

    Murray, Thomas S.; Mendat, Daniel R.; Pouliquen, Philippe O.; Andreou, Andreas G.

    2015-05-01

    The Johns Hopkins University MultiModal Action (JHUMMA) dataset contains a set of twenty-one actions recorded with four sensor systems in three different modalities. The data was collected with a data acquisition system that includes three independent active sonar devices at three different frequencies and a Microsoft Kinect sensor that provides both RGB and Depth data. We have developed algorithms for human action recognition from active acoustics and provide benchmark baseline recognition performance results.

  18. Multimodal images of chronic branch retinal vein occlusion

    PubMed Central

    Schwartz, Stephen G; Monroig, Armando; Flynn, Harry W

    2017-01-01

    Two illustrative cases of chronic branch retinal vein occlusion are presented with multimodal imaging, including commercially available optical coherence tomography angiography. In these two patients, retinal ischemia and collateral vessels were well imaged without the need to use traditional fluorescein angiography. Optical coherence tomography angiography provides useful information for the diagnosis and management of patients with branch retinal vein occlusion and other retinal vascular diseases. PMID:28496373

  19. Multimode-diode-pumped gas (alkali-vapor) laser.

    PubMed

    Page, Ralph H; Beach, Raymond J; Kanz, V Keith; Krupke, William F

    2006-02-01

    We report what we believe to be the first demonstration of a multimode-diode-pumped gas laser: Rb vapor operating on the 795 nm D1 resonance transition. Peak output of approximately 1 W was obtained using a volume-Bragg-grating stabilized pump diode array. The laser's output radiance exceeded the pump radiance by a factor greater than 2000. Power scaling (by pumping with larger diode arrays) is therefore possible.

  20. Multimode tapered optical light pipe for illumination systems

    NASA Astrophysics Data System (ADS)

    Romańczuk, Patryk; Pietrzycki, Marcin; Źmojda, Jacek; Kochanowicz, Marcin; Dorosz, Dominik

    2015-09-01

    In the article the multimode tapered optical light pipe for illumination systems was investigated. Based on tree light emitting diodes at the wavelength of 460 nm (blue), 528 nm (green) and 631 nm (red) possibility of white light emission on the output surface of the tapered light pipe was submitted. Influence of optical power of LEDs on the colour coordinates (CIE-1931) has been investigated.