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Sample records for multipolar induction machine

  1. Induction machine

    SciTech Connect

    Owen, W.H.

    1980-10-14

    A polyphase rotary induction machine for use as a motor or generator utilizes, a single rotor assembly having two series connected sets of rotor windings, a first stator winding disposed around the first rotor winding and means for controlling the current induced in one set of the rotor windings compared to the current induced in the other set of the rotor windings. The rotor windings may be wound rotor windings or squirrel cage windings.

  2. Induction machine

    DOEpatents

    Owen, Whitney H.

    1980-01-01

    A polyphase rotary induction machine for use as a motor or generator utilizing a single rotor assembly having two series connected sets of rotor windings, a first stator winding disposed around the first rotor winding and means for controlling the current induced in one set of the rotor windings compared to the current induced in the other set of the rotor windings. The rotor windings may be wound rotor windings or squirrel cage windings.

  3. Doubly fed induction machine

    DOEpatents

    Skeist, S. Merrill; Baker, Richard H.

    2005-10-11

    An electro-mechanical energy conversion system coupled between an energy source and an energy load including an energy converter device having a doubly fed induction machine coupled between the energy source and the energy load to convert the energy from the energy source and to transfer the converted energy to the energy load and an energy transfer multiplexer coupled to the energy converter device to control the flow of power or energy through the doubly fed induction machine.

  4. Induction of Aneuploidy, Centrosome Abnormality, Multipolar Spindle, and Multipolar Division in Cultured Mammalian Cells Exposed to an Arsenic Metabolite, Dimethylarsinate.

    PubMed

    Ochi, Takafumi

    2016-01-01

    Toxicological studies of arsenic compounds were conducted in cultured mammalian cells to investigate the effects of glutathione (GSH) depletion. Dimethylarsinate DMA(V) was not cytotoxic in cells depleted of GSH, but was found to be cytotoxic when GSH was present outside the cells. The results suggested that a reactive form of DMA(V) was generated through interaction with GSH. Dimethylarsine iodide DMI(III) was used as a model compound of DMA(III), and the biological effects were investigated. DMI(III) was about 10000 times more toxic to the cells than DMA(V). Chromosome structural aberrations and numerical changes, such as aneuploidy, were induced by DMI(III). DMA(V) induced multiple foci of the centrosome protein, γ-tubulin, which were colocalized with multipolar spindles in mitotic cells. The multiple foci coalesced into a single dot on disruption of the microtubules (MT). However, reorganization of the MT caused multiple foci of γ-tubulin, suggesting that the induction of centrosome abnormalities by DMA(V) required intact MT. Inhibition of the MT-dependent motor, kinesin, prevented formation of multiple foci of γ-tubulin, which pointed to the involvement of the MT-dependent mitotic motor, kinesin, in the maintenance of centrosome abnormalities. DMI(III) caused abnormal cytokinesis (multipolar division). In addition, DMI(III) caused morphological transformation in Syrian hamster embryo cells. Consideration of the overall process following the centrosome abnormalities caused by DMA(V) suggested a mode of cytotoxicity in which the mitotic centrosome is a critical target.

  5. Multipolar Electrostatic Energy Prediction for all 20 Natural Amino Acids Using Kriging Machine Learning.

    PubMed

    Fletcher, Timothy L; Popelier, Paul L A

    2016-06-14

    A machine learning method called kriging is applied to the set of all 20 naturally occurring amino acids. Kriging models are built that predict electrostatic multipole moments for all topological atoms in any amino acid based on molecular geometry only. These models then predict molecular electrostatic interaction energies. On the basis of 200 unseen test geometries for each amino acid, no amino acid shows a mean prediction error above 5.3 kJ mol(-1), while the lowest error observed is 2.8 kJ mol(-1). The mean error across the entire set is only 4.2 kJ mol(-1) (or 1 kcal mol(-1)). Charged systems are created by protonating or deprotonating selected amino acids, and these show no significant deviation in prediction error over their neutral counterparts. Similarly, the proposed methodology can also handle amino acids with aromatic side chains, without the need for modification. Thus, we present a generic method capable of accurately capturing multipolar polarizable electrostatics in amino acids.

  6. Multipolar electrostatics based on the Kriging machine learning method: an application to serine.

    PubMed

    Yuan, Yongna; Mills, Matthew J L; Popelier, Paul L A

    2014-04-01

    A multipolar, polarizable electrostatic method for future use in a novel force field is described. Quantum Chemical Topology (QCT) is used to partition the electron density of a chemical system into atoms, then the machine learning method Kriging is used to build models that relate the multipole moments of the atoms to the positions of their surrounding nuclei. The pilot system serine is used to study both the influence of the level of theory and the set of data generator methods used. The latter consists of: (i) sampling of protein structures deposited in the Protein Data Bank (PDB), or (ii) normal mode distortion along either (a) Cartesian coordinates, or (b) redundant internal coordinates. Wavefunctions for the sampled geometries were obtained at the HF/6-31G(d,p), B3LYP/apc-1, and MP2/cc-pVDZ levels of theory, prior to calculation of the atomic multipole moments by volume integration. The average absolute error (over an independent test set of conformations) in the total atom-atom electrostatic interaction energy of serine, using Kriging models built with the three data generator methods is 11.3 kJ mol⁻¹ (PDB), 8.2 kJ mol⁻¹ (Cartesian distortion), and 10.1 kJ mol⁻¹ (redundant internal distortion) at the HF/6-31G(d,p) level. At the B3LYP/apc-1 level, the respective errors are 7.7 kJ mol⁻¹, 6.7 kJ mol⁻¹, and 4.9 kJ mol⁻¹, while at the MP2/cc-pVDZ level they are 6.5 kJ mol⁻¹, 5.3 kJ mol⁻¹, and 4.0 kJ mol⁻¹. The ranges of geometries generated by the redundant internal coordinate distortion and by extraction from the PDB are much wider than the range generated by Cartesian distortion. The atomic multipole moment and electrostatic interaction energy predictions for the B3LYP/apc-1 and MP2/cc-pVDZ levels are similar, and both are better than the corresponding predictions at the HF/6-31G(d,p) level.

  7. Applications of Machine Learning and Rule Induction,

    DTIC Science & Technology

    1995-02-15

    An important area of application for machine learning is in automating the acquisition of knowledge bases required for expert systems. In this paper...we review the major paradigms for machine learning , including neural networks, instance-based methods, genetic learning, rule induction, and analytic

  8. Hybrid-secondary uncluttered induction machine

    DOEpatents

    Hsu, John S.

    2001-01-01

    An uncluttered secondary induction machine (100) includes an uncluttered rotating transformer (66) which is mounted on the same shaft as the rotor (73) of the induction machine. Current in the rotor (73) is electrically connected to current in the rotor winding (67) of the transformer, which is not electrically connected to, but is magnetically coupled to, a stator secondary winding (40). The stator secondary winding (40) is alternately connected to an effective resistance (41), an AC source inverter (42) or a magnetic switch (43) to provide a cost effective slip-energy-controlled, adjustable speed, induction motor that operates over a wide speed range from below synchronous speed to above synchronous speed based on the AC line frequency fed to the stator.

  9. Numerical analysis method for linear induction machines.

    NASA Technical Reports Server (NTRS)

    Elliott, D. G.

    1972-01-01

    A numerical analysis method has been developed for linear induction machines such as liquid metal MHD pumps and generators and linear motors. Arbitrary phase currents or voltages can be specified and the moving conductor can have arbitrary velocity and conductivity variations from point to point. The moving conductor is divided into a mesh and coefficients are calculated for the voltage induced at each mesh point by unit current at every other mesh point. Combining the coefficients with the mesh resistances yields a set of simultaneous equations which are solved for the unknown currents.

  10. Numerical analysis method for linear induction machines.

    NASA Technical Reports Server (NTRS)

    Elliott, D. G.

    1972-01-01

    A numerical analysis method has been developed for linear induction machines such as liquid metal MHD pumps and generators and linear motors. Arbitrary phase currents or voltages can be specified and the moving conductor can have arbitrary velocity and conductivity variations from point to point. The moving conductor is divided into a mesh and coefficients are calculated for the voltage induced at each mesh point by unit current at every other mesh point. Combining the coefficients with the mesh resistances yields a set of simultaneous equations which are solved for the unknown currents.

  11. Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach

    PubMed Central

    Pannu, V; Rida, P C G; Ogden, A; Clewley, R; Cheng, A; Karna, P; Lopus, M; Mishra, R C; Zhou, J; Aneja, R

    2012-01-01

    Centrosome amplification (CA) and resultant chromosomal instability have long been associated with tumorigenesis. However, exacerbation of CA and relentless centrosome declustering engender robust spindle multipolarity (SM) during mitosis and may induce cell death. Recently, we demonstrated that a noscapinoid member, reduced bromonoscapine, (S)-3-(R)-9-bromo-5-(4,5-dimethoxy-1,3-dihydroisobenzofuran-1-yl)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo-[4,5-g]isoquinoline (Red-Br-nos), induces reactive oxygen species (ROS)-mediated autophagy and caspase-independent death in prostate cancer PC-3 cells. Herein, we show that Red-Br-nos induces ROS-dependent DNA damage that resulted in high-grade CA and SM in PC-3 cells. Unlike doxorubicin, which causes double-stranded DNA breaks and chronic G2 arrest accompanied by ‘templated' CA, Red-Br-nos-mediated DNA damage elicits de novo CA during a transient S/G2 stall, followed by checkpoint abrogation and mitotic entry to form aberrant mitotic figures with supernumerary spindle poles. Attenuation of multipolar phenotype in the presence of tiron, a ROS inhibitor, indicated that ROS-mediated DNA damage was partly responsible for driving CA and SM. Although a few cells (∼5%) yielded to aberrant cytokinesis following an ‘anaphase catastrophe', most mitotically arrested cells (∼70%) succumbed to ‘metaphase catastrophe,' which was caspase-independent. This report is the first documentation of rapid de novo centrosome formation in the presence of parent centrosome by a noscapinoid family member, which triggers death-inducing SM via a unique mechanism that distinguishes it from other ROS-inducers, conventional DNA-damaging agents, as well as other microtubule-binding drugs. PMID:22785532

  12. Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach.

    PubMed

    Pannu, V; Rida, P C G; Ogden, A; Clewley, R; Cheng, A; Karna, P; Lopus, M; Mishra, R C; Zhou, J; Aneja, R

    2012-07-12

    Centrosome amplification (CA) and resultant chromosomal instability have long been associated with tumorigenesis. However, exacerbation of CA and relentless centrosome declustering engender robust spindle multipolarity (SM) during mitosis and may induce cell death. Recently, we demonstrated that a noscapinoid member, reduced bromonoscapine, (S)-3-(R)-9-bromo-5-(4,5-dimethoxy-1,3-dihydroisobenzofuran-1-yl)-4-methoxy-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo-[4,5-g]isoquinoline (Red-Br-nos), induces reactive oxygen species (ROS)-mediated autophagy and caspase-independent death in prostate cancer PC-3 cells. Herein, we show that Red-Br-nos induces ROS-dependent DNA damage that resulted in high-grade CA and SM in PC-3 cells. Unlike doxorubicin, which causes double-stranded DNA breaks and chronic G2 arrest accompanied by 'templated' CA, Red-Br-nos-mediated DNA damage elicits de novo CA during a transient S/G2 stall, followed by checkpoint abrogation and mitotic entry to form aberrant mitotic figures with supernumerary spindle poles. Attenuation of multipolar phenotype in the presence of tiron, a ROS inhibitor, indicated that ROS-mediated DNA damage was partly responsible for driving CA and SM. Although a few cells (∼5%) yielded to aberrant cytokinesis following an 'anaphase catastrophe', most mitotically arrested cells (∼70%) succumbed to 'metaphase catastrophe,' which was caspase-independent. This report is the first documentation of rapid de novo centrosome formation in the presence of parent centrosome by a noscapinoid family member, which triggers death-inducing SM via a unique mechanism that distinguishes it from other ROS-inducers, conventional DNA-damaging agents, as well as other microtubule-binding drugs.

  13. Multipolar electrostatics.

    PubMed

    Cardamone, Salvatore; Hughes, Timothy J; Popelier, Paul L A

    2014-06-14

    Atomistic simulation of chemical systems is currently limited by the elementary description of electrostatics that atomic point-charges offer. Unfortunately, a model of one point-charge for each atom fails to capture the anisotropic nature of electronic features such as lone pairs or π-systems. Higher order electrostatic terms, such as those offered by a multipole moment expansion, naturally recover these important electronic features. The question remains as to why such a description has not yet been widely adopted by popular molecular mechanics force fields. There are two widely-held misconceptions about the more rigorous formalism of multipolar electrostatics: (1) Accuracy: the implementation of multipole moments, compared to point-charges, offers little to no advantage in terms of an accurate representation of a system's energetics, structure and dynamics. (2) Efficiency: atomistic simulation using multipole moments is computationally prohibitive compared to simulation using point-charges. Whilst the second of these may have found some basis when computational power was a limiting factor, the first has no theoretical grounding. In the current work, we disprove the two statements above and systematically demonstrate that multipole moments are not discredited by either. We hope that this perspective will help in catalysing the transition to more realistic electrostatic modelling, to be adopted by popular molecular simulation software.

  14. Pulse-Population Modulation For Induction Machines

    NASA Technical Reports Server (NTRS)

    Hansen, Irving G.

    1989-01-01

    Low-frequency synthesizer developed to provide low-frequency waveform by synthesis from high-frequency power system. Waveform assembled by allowing conduction of discrete half cycles of high-frequency carrier. Frequency of synthesized wave controlled by pulse pattern. By controlling relationship between slip and stator frequencies, one operates induction motor either as motor or generator. Such bidirectional energy transducer used as starter/generator for engine, or as servo-mechanism for control of acceleration and deceleration. Other advantages include operation under controlled voltage-to-frequency ratios to maintain high-efficiency and high power factor, and no reflection of low-frequency noise into 20-kHz distribution bus.

  15. Induction machine condition monitoring using notch-filtered motor current

    NASA Astrophysics Data System (ADS)

    Günal, Serkan; Gökhan Ece, Dog˜an; Nezih Gerek, Ömer

    2009-11-01

    This paper presents a new approach to induction motor condition monitoring using notch-filtered motor current signature analysis (NFMCSA). Unlike most of the previous work utilizing motor current signature analysis (MCSA) using spectral methods to extract required features for detecting motor fault conditions, here NFMCSA is performed in time-domain to extract features of energy, sample extrema, and third and fourth cumulants evaluated from data within sliding time window. Six identical three-phase induction motors were used for the experimental verification of the proposed method. One healthy machine was used as a reference, while other five with different synthetic faults were used for condition detection and classification. Extracted features obtained from NFMCSA of all motors were employed in three different and popular classifiers. The proposed motor current analysis and the performance of the features used for fault detection and classification are examined at various motor load levels and it is shown that a successful induction motor condition monitoring system is developed. Developed system is also able to indicate the load level and the type of a fault in multi-dimensional feature space representation. In order to test the generality and applicability of the developed method to other induction motors, data acquired from another healthy induction motor with different number of poles and rated power is also incorporated into the system. In spite of the above difference, the proposed feature set successfully locates the healthy motor within the classification cluster of "healthy motors" on the feature space.

  16. Stator-flux-based vector control of induction machines in magnetic saturation

    SciTech Connect

    Hofmann, H.; Sanders, S.R.; Sullivan, C.

    1995-12-31

    In many variable-torque applications of induction machines it is desirable to operate the machine in magnetic saturation, thus allowing the machine to produce higher torques. Stator-flux-based control schemes have been developed as a possible alternative method of control of induction machines. Stator-flux-based control schemes need not depend on the magnetic characteristics of the machine, and hence are potentially more robust and easier to implement in magnetic saturation than rotor-flux-based control. The authors analyze the induction machine in saturation using a nonlinear {pi}-model of the machine`s magnetics, and develop a control scheme in the stator flux reference frame that is independent of magnetics. Experiments carried out on a 3 hp, 1,800 rpm wound rotor induction machine show smooth operation of the control scheme at torque levels up to at least 4 times rated torque.

  17. Pole-phase modulated toroidal winding for an induction machine

    SciTech Connect

    Miller, J.M.; Ostovic, V.

    1999-11-02

    A stator (10) for an induction machine for a vehicle has a cylindrical core (12) with inner and outer slots (26, 28) extending longitudinally along the inner and outer peripheries between the end faces (22, 24). Each outer slot is associated with several adjacent inner slots. A plurality of toroidal coils (14) are wound about the core and laid in the inner and outer slots. Each coil occupies a single inner slot and is laid in the associated outer slot thereby minimizing the distance the coil extends from the end faces and minimizing the length of the induction machine. The toroidal coils are configured for an arbitrary pole phase modulation wherein the coils are configured with variable numbers of phases and poles for providing maximum torque for cranking and switchable to another phase and pole configuration for alternator operation. An adaptor ring (36) circumferentially positioned about the stator improves mechanical strength, and provides a coolant channel manifold (34) for removing heat produced in stator windings during operation.

  18. Pole-phase modulated toroidal winding for an induction machine

    DOEpatents

    Miller, John Michael; Ostovic, Vlado

    1999-11-02

    A stator (10) for an induction machine for a vehicle has a cylindrical core (12) with inner and outer slots (26, 28) extending longitudinally along the inner and outer peripheries between the end faces (22, 24). Each outer slot is associated with several adjacent inner slots. A plurality of toroidal coils (14) are wound about the core and laid in the inner and outer slots. Each coil occupies a single inner slot and is laid in the associated outer slot thereby minimizing the distance the coil extends from the end faces and minimizing the length of the induction machine. The toroidal coils are configured for an arbitrary pole phase modulation wherein the coils are configured with variable numbers of phases and poles for providing maximum torque for cranking and switchable to a another phase and pole configuration for alternator operation. An adaptor ring (36) circumferentially positioned about the stator improves mechanical strength, and provides a coolant channel manifold (34) for removing heat produced in stator windings during operation.

  19. Emulation of Wind Power with a DC Machine to Provide Input to a Doubly-Fed Induction Machine

    DTIC Science & Technology

    2012-03-01

    The behavioral modeling of a separately excited direct current ( DC ) motor as a prime mover for a doubly-fed induction machine (DFIM) is studied in...this thesis. The output torque of the DC motor is computed in the simulation under controlled parameters. The input to the DFIM, used as a doubly-fed...induction generator (DFIG), is taken from the DC motor . In theory, the combination of the two machines can be used to emulate various wind patterns and

  20. [Rule induction algorithm for brain glioma using support vector machine].

    PubMed

    Li, Guozheng; Yang, Jie; Wang, Jiaju; Geng, Daoying

    2006-04-01

    A new proposed data mining technique, support vector machine (SVM), is used to predict the degree of malignancy in brain glioma. Based on statistical learning theory, SVM realizes the principle of data dependent structure risk minimization, so it can depress the overfitting with better generalization performance, since the prediction in medical diagnosis often deals with a small sample. SVM based rule induction algorithm is implemented in comparison with other data mining techniques such as artificial neural networks, rule induction algorithm and fuzzy rule extraction algorithm based on fuzzy max-min neural networks (FRE-FMMNN) proposed recently. Computation results by 10 fold cross validation method show that SVM can get higher prediction accuracy than artificial neural networks and FRE-FMMNN, which implies SVM can get higher accuracy and more reliability. On the whole data sets, SVM gets one rule with the classification accuracy of 89.29%, while FRE-FMMNN gets two rules of 84. 64%, in which the rule got by SVM is of quantity relation and contains more information than the two rules by FRE-FMMNN. All the above show SVM is a potential algorithm for the medical diagnosis such as the prediction of the degree of malignancy in brain glioma.

  1. Optimal efficiency vector control of induction motor drive system for drum washing machine

    NASA Astrophysics Data System (ADS)

    Lee, Won Cheol; Yu, Jae Sung; Jang, Bong An; Won, Chung Yuen

    2005-12-01

    In home appliances, electric energy is optimally controlled by using power electronics technology, creating a comfortable environment in terms of energy saving, low sound generation, and reduced time consumption. Usually simplicity and robustness make the three phase induction motor attractive for use in domestic appliance, including washing machines. Two main types of domestic washing machine have evolved. We focus on efficiency of the front loading machine favored in Europe, which has a horizontal drum axis. This paper presents the control algorithm for optimal efficiency drives of an induction motor for drum washing machine. This system uses a simple model of the induction motor that include equations of the iron losses. The proposed optimal efficiency control algorithm calculates commands of the reference torque and flux currents for the flux oriented control of the induction motor. The proposed algorithm is verified through digital simulation.

  2. Multipolar ECR plasma characterization

    SciTech Connect

    Ciubotariu, C.I.; Golovanivsky, K.S.; Bacal, M.

    1995-12-31

    There has been considerable interest in the development of intense negative ion sources for use in high-energy neutral beam heating and diagnostics systems for nuclear fusion plasmas. As it was shown by one of the authors overdense ECR plasmas seem to be an appropriate medium to produce H-ions at high rate. Overdense plasmas are a result of the microwave({mu}wave) power absorption in ECR plasma heating and magnetic field confinement. Our aim is to characterize the hydrogen plasma produced in a 2.45 GHz multipolar negative ion ECR source (ECRIN).

  3. High Performances of Five-Phase Induction Machine Feeding by A [3 × 5] Matrix Converter

    NASA Astrophysics Data System (ADS)

    Rezaoui, Mohamed Mounir; Nezli, Lazhari; Mahmoudi, Mohand Oulhadj

    2014-03-01

    In this paper, we study an analytic technique to control matrix converter for a four-quadrant five-phase induction machine drive with use PWM five intervals modulation strategy. The multiphase induction machine is feeding by a matrix converter using a three-phase network. Special emphasis is given to the sinusoidal five phase voltage in the output and five phase voltage input current modulation. Simulation results are presented.

  4. Doubly Fed Induction Machine Control For Wind Energy Conversion System

    DTIC Science & Technology

    2009-06-01

    Induction Generator (DFIG), Voltage Source Inverter (VSI), Space Vector Modulation (SVM), Wind Turbine, Field Programmable Gate Array ( FPGA ), Wind...basics of using a doubly-fed induction generator (DFIG) to convert the mechanical energy of the wind into useful electrical power that can be used to...thesis covers the basics of using a doubly-fed induction generator (DFIG) to convert the mechanical energy of the wind into useful electrical power

  5. Magnetic Induction Machines Integrated into Bulk-Micromachined Silicon

    DTIC Science & Technology

    2006-04-01

    machines were characterized in three stages: (A) electrical measurements of the stators, (B) ferrofluid tests of the stator, and (C) tethered rotor torque...the upper and lower coils for each machine. B. Ferrofluid Tests A ferrofluid , a colloidal suspension of magnetic particles in a liquid (oil) carrier...Kapton film and placed over the stator, as shown in Fig. 10. The tub was filled with a thin layer of ferrofluid (Ferrotec Corporation, Nashua, NH) that

  6. Comparison of Alternative Equivalent Circuits of Induction Motor with Real Machine Data

    NASA Astrophysics Data System (ADS)

    Bradna, J.; Bauer, J.; Fligl, S.; Hlinovsky, V.

    The algorithms based on separated control of the motor flux and torque is used in order to gain the maximum performance from the induction machine. To push the efficiency and dynamics limits of the IM to its limits mostly FOC or DTC control strategies are used. Both are based on the knowledge of the hardly measurable variable-machine flux. To obtain the information about inner machine flux models based on the machine equivalent circuit are mostly used. Therefore the accuracy of the equivalent circuits has direct influence on the accuracy of the machine control. To reduce the complexity of the mathematical model the resistances and inductances are concentrated to one component and three phase winding is assumed to be symmetrical. In order to design control strategy for the induction motor, system equations and equivalent circuit must be established at first. This paper examines and compares some of the issues of adequate machine modeling and attempts to provide a firmer basis for selection of an appropriate model and to confirm or disprove the equivalence of different approaches. The results of the IM model run up are then compared to the results obtained from the measurements on the real machine and the equivalency is discussed.

  7. Electric Machine with Boosted Inductance to Stabilize Current Control

    NASA Technical Reports Server (NTRS)

    Abel, Steve

    2013-01-01

    High-powered motors typically have very low resistance and inductance (R and L) in their windings. This makes the pulse-width modulated (PWM) control of the current very difficult, especially when the bus voltage (V) is high. These R and L values are dictated by the motor size, torque (Kt), and back-emf (Kb) constants. These constants are in turn set by the voltage and the actuation torque-speed requirements. This problem is often addressed by placing inductive chokes within the controller. This approach is undesirable in that space is taken and heat is added to the controller. By keeping the same motor frame, reducing the wire size, and placing a correspondingly larger number of turns in each slot, the resistance, inductance, torque constant, and back-emf constant are all increased. The increased inductance aids the current control but ruins the Kt and Kb selections. If, however, a fraction of the turns is moved from their "correct slot" to an "incorrect slot," the increased R and L values are retained, but the Kt and Kb values are restored to the desired values. This approach assumes that increased resistance is acceptable to a degree. In effect, the heat allocated to the added inductance has been moved from the controller to the motor body, which in some cases is preferred.

  8. Field oriented control of an induction machine in a high frequency link power system

    NASA Technical Reports Server (NTRS)

    Sul, Seung K.; Lipo, Thomas A.

    1988-01-01

    A field-oriented controlled induction machine drive operating with a high-frequency single-phase sinusoidal voltage link is presented. System performance is investigated by computer simulation and is verified by a test on a prototype system. A novel control loop to minimize the link voltage fluctuation is proposed. The capability of rapid demagnetization of the induction machine by current regulation is investigated. A current-modulation technique termed mode control is proposed, and its performance is compared with that of the conventional delta-modulation technique.

  9. Capacitance and Inductance based Rotor Ground Fault Location Method for Synchronous Machines

    NASA Astrophysics Data System (ADS)

    Palanisamy, Ramanathan

    2017-02-01

    This paper presents a capacitance and inductance based rotor ground fault location method for synchronous machines, which can detect and locate the ground fault in the rotor. The main contribution of this technique is to find the location of the ground fault in the rotor winding and reduce the repair time. This detection method is based on the measurement of inductance and capacitance of the rotor winding. It is suitable for salient pole synchronous machines. This method has been validated through experimental tests at the site.

  10. Induction squirrel cage machine design with minimization of electromagnetic noise

    SciTech Connect

    Hadj Amor, A.; Timar, P.L.; Poloujadoff, M.

    1995-12-01

    The noise created by an induction motor design, satisfying given specifications, is a function of eight independent variables. Its minimum value may be found by any unconstrained optimization technique. The minimum noise corresponds to a very expensive and heavy motor; therefore the conflict of interest must be dealt with. It is shown that the optimum design is independent of eccentricity.

  11. Induced electric fields in workers near low-frequency induction heating machines.

    PubMed

    Kos, Bor; Valič, Blaž; Kotnik, Tadej; Gajšek, Peter

    2014-04-01

    Published data on occupational exposure to induction heating equipment are scarce, particularly in terms of induced quantities in the human body. This article provides some additional information by investigating exposure to two such machines-an induction furnace and an induction hardening machine. Additionally, a spatial averaging algorithm for measured fields we developed in a previous publication is tested on new data. The human model was positioned at distances where measured values of magnetic flux density were above the reference levels. All human exposure was below the basic restriction-the lower bound of the 0.1 top percentile induced electric field in the body of a worker was 0.193 V/m at 30 cm from the induction furnace.

  12. Angular position adaptive control of a squirrel-cage-induction-machine

    SciTech Connect

    Bonilla, M.E.; Amestegui, O.M.M.; Siller-Alcala, I.I.; Galindo, R.O.

    1994-12-31

    We consider a control scheme of a squiared-cage-induction-machine which maximize the power factor and control the angular position. An adaptive control is developed since the parameters of the motor (inductances l{sub s} and l{sub r} and in particular the rotor resistance R{sub t}) change greatly with temperature and/or magnetic saturation as well as uncertainty in the measurement of any of the parameters.

  13. Application and design of induction machine damping unit (IMDU) for eliminating subsynchronous resonance

    NASA Astrophysics Data System (ADS)

    Purushothaman, Sujit

    The IEEE First and Second Benchmark Models for subsynchronous resonance (SSR) are used to analyze the damping properties of an induction machine damping unit (IMDU) coupled to the shaft of a turbo-generator set. This study investigates the rating and location of the induction machine that, without the aid of any controllers, effectively damps sub-synchronous resonance for all line series compensation levels. Eigenvalue analyses are performed on linearized models of the shaft system including the induction machine to find the optimum location. The best location of the IMDU, providing maximum damping, is next to the HP turbine at the end of the shaft. Time domain simulations are conducted to find the adequate rating of the induction machine. It is observed that a small size, high power (about 10% of the generator rating), low energy machine effectively damps SSR. The IMDU reduces peak torques in shaft sections during transients. In the study, it is demonstrated that the addition of an IMDU at the end of the shaft would have prevented the SSR events of 1970 and 1971 that caused major damage to the Mohave Desert generator shafts. A basic design of the IMDU is presented derived from a closed form solution of Maxwell's equations in squirrel cage induction motors. The solution is obtained for a cylindrical multi-layer geometry. The squirrel cage is represented by an equivalent anisotropic homogeneous medium. The effect of stator slots and teeth is included by a second anisotropic homogeneous medium. The induction motor is modeled as six concentric cylindrical layers representing the different construction components of the motor. The governing partial differential equations are solved for the excitation source, conducting and non-conducting regions. The formulas obtained allow for efficient calculations of machine performance which may help the motor designer to select the proper parameters of the machine that fit the design requirements. Accuracy of the modeling method

  14. Diagnosis of broken-bars fault in induction machines using higher order spectral analysis.

    PubMed

    Saidi, L; Fnaiech, F; Henao, H; Capolino, G-A; Cirrincione, G

    2013-01-01

    Detection and identification of induction machine faults through the stator current signal using higher order spectra analysis is presented. This technique is known as motor current signature analysis (MCSA). This paper proposes two higher order spectra techniques, namely the power spectrum and the slices of bi-spectrum used for the analysis of induction machine stator current leading to the detection of electrical failures within the rotor cage. The method has been tested by using both healthy and broken rotor bars cases for an 18.5 kW-220 V/380 V-50 Hz-2 pair of poles induction motor under different load conditions. Experimental signals have been analyzed highlighting that bi-spectrum results show their superiority in the accurate detection of rotor broken bars. Even when the induction machine is rotating at a low level of shaft load (no-load condition), the rotor fault detection is efficient. We will also demonstrate through the analysis and experimental verification, that our proposed proposed-method has better detection performance in terms of receiver operation characteristics (ROC) curves and precision-recall graph.

  15. Sensorless speed detection of squirrel-cage induction machines using stator neutral point voltage harmonics

    NASA Astrophysics Data System (ADS)

    Petrovic, Goran; Kilic, Tomislav; Terzic, Bozo

    2009-04-01

    In this paper a sensorless speed detection method of induction squirrel-cage machines is presented. This method is based on frequency determination of the stator neutral point voltage primary slot harmonic, which is dependent on rotor speed. In order to prove method in steady state and dynamic conditions the simulation and experimental study was carried out. For theoretical investigation the mathematical model of squirrel cage induction machines, which takes into consideration actual geometry and windings layout, is used. Speed-related harmonics that arise from rotor slotting are analyzed using digital signal processing and DFT algorithm with Hanning window. The performance of the method is demonstrated over a wide range of load conditions.

  16. A Novel Approach for Multi Class Fault Diagnosis in Induction Machine Based on Statistical Time Features and Random Forest Classifier

    NASA Astrophysics Data System (ADS)

    Sonje, M. Deepak; Kundu, P.; Chowdhury, A.

    2017-08-01

    Fault diagnosis and detection is the important area in health monitoring of electrical machines. This paper proposes the recently developed machine learning classifier for multi class fault diagnosis in induction machine. The classification is based on random forest (RF) algorithm. Initially, stator currents are acquired from the induction machine under various conditions. After preprocessing the currents, fourteen statistical time features are estimated for each phase of the current. These parameters are considered as inputs to the classifier. The main scope of the paper is to evaluate effectiveness of RF classifier for individual and mixed fault diagnosis in induction machine. The stator, rotor and mixed faults (stator and rotor faults) are classified using the proposed classifier. The obtained performance measures are compared with the multilayer perceptron neural network (MLPNN) classifier. The results show the much better performance measures and more accurate than MLPNN classifier. For demonstration of planned fault diagnosis algorithm, experimentally obtained results are considered to build the classifier more practical.

  17. Multipolar interference effects in nanophotonics

    NASA Astrophysics Data System (ADS)

    Liu, Wei; Kivshar, Yuri S.

    2017-03-01

    Scattering of electromagnetic waves by an arbitrary nanoscale object can be characterized by a multipole decomposition of the electromagnetic field that allows one to describe the scattering intensity and radiation pattern through interferences of dominating multipole modes excited. In modern nanophotonics, both generation and interference of multipole modes start to play an indispensable role, and they enable nanoscale manipulation of light with many related applications. Here, we review the multipolar interference effects in metallic, metal-dielectric and dielectric nanostructures, and suggest a comprehensive view on many phenomena involving the interferences of electric, magnetic and toroidal multipoles, which drive a number of recently discussed effects in nanophotonics such as unidirectional scattering, effective optical antiferromagnetism, generalized Kerker scattering with controlled angular patterns, generalized Brewster angle, and non-radiating optical anapoles. We further discuss other types of possible multipolar interference effects not yet exploited in the literature and envisage the prospect of achieving more flexible and advanced nanoscale control of light relying on the concepts of multipolar interference through full phase and amplitude engineering. This article is part of the themed issue 'New horizons for nanophotonics'.

  18. Multipolar interference effects in nanophotonics.

    PubMed

    Liu, Wei; Kivshar, Yuri S

    2017-03-28

    Scattering of electromagnetic waves by an arbitrary nanoscale object can be characterized by a multipole decomposition of the electromagnetic field that allows one to describe the scattering intensity and radiation pattern through interferences of dominating multipole modes excited. In modern nanophotonics, both generation and interference of multipole modes start to play an indispensable role, and they enable nanoscale manipulation of light with many related applications. Here, we review the multipolar interference effects in metallic, metal-dielectric and dielectric nanostructures, and suggest a comprehensive view on many phenomena involving the interferences of electric, magnetic and toroidal multipoles, which drive a number of recently discussed effects in nanophotonics such as unidirectional scattering, effective optical antiferromagnetism, generalized Kerker scattering with controlled angular patterns, generalized Brewster angle, and non-radiating optical anapoles. We further discuss other types of possible multipolar interference effects not yet exploited in the literature and envisage the prospect of achieving more flexible and advanced nanoscale control of light relying on the concepts of multipolar interference through full phase and amplitude engineering.This article is part of the themed issue 'New horizons for nanophotonics'.

  19. Single-trial classification of NIRS signals during emotional induction tasks: towards a corporeal machine interface.

    PubMed

    Tai, Kelly; Chau, Tom

    2009-11-09

    Corporeal machine interfaces (CMIs) are one of a few available options for restoring communication and environmental control to those with severe motor impairments. Cognitive processes detectable solely with functional imaging technologies such as near-infrared spectroscopy (NIRS) can potentially provide interfaces requiring less user training than conventional electroencephalography-based CMIs. We hypothesized that visually-cued emotional induction tasks can elicit forehead hemodynamic activity that can be harnessed for a CMI. Data were collected from ten able-bodied participants as they performed trials of positively and negatively-emotional induction tasks. A genetic algorithm was employed to select the optimal signal features, classifier, task valence (positive or negative emotional value of the stimulus), recording site, and signal analysis interval length for each participant. We compared the performance of Linear Discriminant Analysis and Support Vector Machine classifiers. The latency of the NIRS hemodynamic response was estimated as the time required for classification accuracy to stabilize. Baseline and activation sequences were classified offline with accuracies upwards of 75.0%. Feature selection identified common time-domain discriminatory features across participants. Classification performance varied with the length of the input signal, and optimal signal length was found to be feature-dependent. Statistically significant increases in classification accuracy from baseline rates were observed as early as 2.5 s from initial stimulus presentation. NIRS signals during affective states were shown to be distinguishable from baseline states with classification accuracies significantly above chance levels. Further research with NIRS for corporeal machine interfaces is warranted.

  20. New Technique of High-Performance Torque Control Developed for Induction Machines

    NASA Technical Reports Server (NTRS)

    Kenny, Barbara H.

    2003-01-01

    Two forms of high-performance torque control for motor drives have been described in the literature: field orientation control and direct torque control. Field orientation control has been the method of choice for previous NASA electromechanical actuator research efforts with induction motors. Direct torque control has the potential to offer some advantages over field orientation, including ease of implementation and faster response. However, the most common form of direct torque control is not suitable for the highspeed, low-stator-flux linkage induction machines designed for electromechanical actuators with the presently available sample rates of digital control systems (higher sample rates are required). In addition, this form of direct torque control is not suitable for the addition of a high-frequency carrier signal necessary for the "self-sensing" (sensorless) position estimation technique. This technique enables low- and zero-speed position sensorless operation of the machine. Sensorless operation is desirable to reduce the number of necessary feedback signals and transducers, thus improving the reliability and reducing the mass and volume of the system. This research was directed at developing an alternative form of direct torque control known as a "deadbeat," or inverse model, solution. This form uses pulse-width modulation of the voltage applied to the machine, thus reducing the necessary sample and switching frequency for the high-speed NASA motor. In addition, the structure of the deadbeat form allows the addition of the high-frequency carrier signal so that low- and zero-speed sensorless operation is possible. The new deadbeat solution is based on using the stator and rotor flux as state variables. This choice of state variables leads to a simple graphical representation of the solution as the intersection of a constant torque line with a constant stator flux circle. Previous solutions have been expressed only in complex mathematical terms without a

  1. A modular approach to the simulation of doubly-fed induction machine systems

    SciTech Connect

    Vasudevan, K.; Rao, P.S.

    1995-12-31

    Wound rotor induction machines with a variety of switching circuitry connected to the rotor side as well are used in many applications. This is especially true in applications where the rotor power is considerable. This paper presents a modular approach for simulating such systems. Changes in the mode of operation due to switch changes are taken care of automatically. Shorting of the rotor terminals automatically simulates a stator-fed operation. The approach and algorithm presented here are validated by excellent agreement with the results of earlier research workers.

  2. Fuzzy logic enhanced speed control of an indirect field-oriented induction machine drive

    SciTech Connect

    Heber, B.; Xu, L.; Tang, Y.

    1997-09-01

    Field orientation control (FOC) of induction machines has permitted fast transient response by decoupled torque and flux control. However, field orientation detuning caused by parameter variations is a major difficulty for indirect FOC methods. Traditional probability density function (PID) controllers have trouble meeting a wide range of speed tracking performance even when proper field orientation is achieved. PID controller performance is severely degraded when detuning occurs. This paper presents a fuzzy logic design approach that can meet the speed tracking requirements even when detuning occurs. Computer simulations and experimental results obtained via a general-purpose digital signal processor (DSP) system are presented.

  3. Feedback linearisation control of an induction machine augmented by single-hidden layer neural networks

    NASA Astrophysics Data System (ADS)

    Ait Abbas, Hamou; Belkheiri, Mohammed; Zegnini, Boubakeur

    2016-01-01

    We consider adaptive output feedback control methodology of highly uncertain nonlinear systems with both parametric uncertainties and unmodelled dynamics. The approach is also applicable to systems of unknown, but bounded dimension. However, the relative degree of the regulated output is assumed to be known. This new control strategy is proposed to address the tracking problem of an induction motor based on a modified field-oriented control method. The obtained controller is then augmented by an online neural network that serves as an approximator for the neglected dynamics and modelling errors. The network weight adaptation rule is derived from the Lyapunov stability analysis, that guarantees boundedness of all the error signals of the closed-loop system. Computer simulations of an output feedback controlled induction machine, augmented via single-hidden-layer neural networks, demonstrate the practical potential of the proposed control algorithm.

  4. Single-trial classification of NIRS signals during emotional induction tasks: towards a corporeal machine interface

    PubMed Central

    2009-01-01

    Background Corporeal machine interfaces (CMIs) are one of a few available options for restoring communication and environmental control to those with severe motor impairments. Cognitive processes detectable solely with functional imaging technologies such as near-infrared spectroscopy (NIRS) can potentially provide interfaces requiring less user training than conventional electroencephalography-based CMIs. We hypothesized that visually-cued emotional induction tasks can elicit forehead hemodynamic activity that can be harnessed for a CMI. Methods Data were collected from ten able-bodied participants as they performed trials of positively and negatively-emotional induction tasks. A genetic algorithm was employed to select the optimal signal features, classifier, task valence (positive or negative emotional value of the stimulus), recording site, and signal analysis interval length for each participant. We compared the performance of Linear Discriminant Analysis and Support Vector Machine classifiers. The latency of the NIRS hemodynamic response was estimated as the time required for classification accuracy to stabilize. Results Baseline and activation sequences were classified offline with accuracies upwards of 75.0%. Feature selection identified common time-domain discriminatory features across participants. Classification performance varied with the length of the input signal, and optimal signal length was found to be feature-dependent. Statistically significant increases in classification accuracy from baseline rates were observed as early as 2.5 s from initial stimulus presentation. Conclusion NIRS signals during affective states were shown to be distinguishable from baseline states with classification accuracies significantly above chance levels. Further research with NIRS for corporeal machine interfaces is warranted. PMID:19900285

  5. Inductive machine learning for improved estimation of catchment-scale snow water equivalent

    NASA Astrophysics Data System (ADS)

    Buckingham, David; Skalka, Christian; Bongard, Josh

    2015-05-01

    Infrastructure for the automatic collection of single-point measurements of snow water equivalent (SWE) is well-established. However, because SWE varies significantly over space, the estimation of SWE at the catchment scale based on a single-point measurement is error-prone. We propose low-cost, lightweight methods for near-real-time estimation of mean catchment-wide SWE using existing infrastructure, wireless sensor networks, and machine learning algorithms. Because snowpack distribution is highly nonlinear, we focus on Genetic Programming (GP), a nonlinear, white-box, inductive machine learning algorithm. Because we did not have access to near-real-time catchment-scale SWE data, we used available data as ground truth for machine learning in a set of experiments that are successive approximations of our goal of catchment-wide SWE estimation. First, we used a history of maritime snowpack data collected by manual snow courses. Second, we used distributed snow depth (HS) data collected automatically by wireless sensor networks. We compared the performance of GP against linear regression (LR), binary regression trees (BT), and a widely used basic method (BM) that naively assumes non-variable snowpack. In the first experiment set, GP and LR models predicted SWE with lower error than BM. In the second experiment set, GP had lower error than LR, but outperformed BT only when we applied a technique that specifically mitigated the possibility of over-fitting.

  6. Libration-driven multipolar instabilities

    NASA Astrophysics Data System (ADS)

    Cébron, D.; Vantieghem, S.; Herreman, W.

    2014-01-01

    We consider rotating flows in non-axisymmetric enclosures that are driven by libration, i.e. by a small periodic modulation of the rotation rate. Thanks to its simplicity, this model is relevant to various contexts, from industrial containers (with small oscillations of the rotation rate) to fluid layers of terrestial planets (with length-of-day variations). Assuming a multipolar $n$-fold boundary deformation, we first obtain the two-dimensional basic flow. We then perform a short-wavelength local stability analysis of the basic flow, showing that an instability may occur in three dimensions. We christen it the Libration Driven Multipolar Instability (LDMI). The growth rates of the LDMI are computed by a Floquet analysis in a systematic way, and compared to analytical expressions obtained by perturbation methods. We then focus on the simplest geometry allowing the LDMI, a librating deformed cylinder. To take into account viscous and confinement effects, we perform a global stability analysis, which shows that the LDMI results from a parametric resonance of inertial modes. Performing numerical simulations of this librating cylinder, we confirm that the basic flow is indeed established and report the first numerical evidence of the LDMI. Numerical results, in excellent agreement with the stability results, are used to explore the non-linear regime of the instability (amplitude and viscous dissipation of the driven flow). We finally provide an example of LDMI in a deformed spherical container to show that the instability mechanism is generic. Our results show that the previously studied libration driven elliptical instability simply corresponds to the particular case $n=2$ of a wider class of instabilities. Summarizing, this work shows that any oscillating non-axisymmetric container in rotation may excite intermittent, space-filling LDMI flows, and this instability should thus be easy to observe experimentally.

  7. Eddy current loss and coil inductance evaluation in DC machines by a PG-based F. E. Code

    SciTech Connect

    Arturi, C.M.; Ubaldini, M. )

    1991-09-01

    The present paper deals with the evaluation of both the eddy current loss and the self and mutual inductances of the commutating coils of a dc machine armature-winding for railway traction by a two-dimension PC-based finite element commercial code. The comparison among several distribution of the conductors occupying a given slot and among slots with different ratio of depth to width is made in this paper in order to determine, for a given dc machine, the best design solution with references to both the loss and the self and mutual inductances of the commutating coils.

  8. Method for reducing peak phase current and decreasing staring time for an internal combustion engine having an induction machine

    DOEpatents

    Amey, David L.; Degner, Michael W.

    2002-01-01

    A method for reducing the starting time and reducing the peak phase currents for an internal combustion engine that is started using an induction machine starter/alternator. The starting time is reduced by pre-fluxing the induction machine and the peak phase currents are reduced by reducing the flux current command after a predetermined period of time has elapsed and concurrent to the application of the torque current command. The method of the present invention also provides a strategy for anticipating the start command for an internal combustion engine and determines a start strategy based on the start command and the operating state of the internal combustion engine.

  9. Grid-connected in-stream hydroelectric generation based on the doubly fed induction machine

    NASA Astrophysics Data System (ADS)

    Lenberg, Timothy J.

    Within the United States, there is a growing demand for new environmentally friendly power generation. This has led to a surge in wind turbine development. Unfortunately, wind is not a stable prime mover, but water is. Why not apply the advances made for wind to in-stream hydroelectric generation? One important advancement is the creation of the Doubly Fed Induction Machine (DFIM). This thesis covers the application of a gearless DFIM topology for hydrokinetic generation. After providing background, this thesis presents many of the options available for the mechanical portion of the design. A mechanical turbine is then specified. Next, a method is presented for designing a DFIM including the actual design for this application. In Chapter 4, a simulation model of the system is presented, complete with a control system that maximizes power generation based on water speed. This section then goes on to present simulation results demonstrating proper operation.

  10. Comparative investigation of diagnosis media for induction machine mechanical unbalance fault.

    PubMed

    Salah, Mohamed; Bacha, Khmais; Chaari, Abdelkader

    2013-11-01

    For an induction machine, we suggest a theoretical development of the mechanical unbalance effect on the analytical expressions of radial vibration and stator current. Related spectra are described and characteristic defect frequencies are determined. Moreover, the stray flux expressions are developed for both axial and radial sensor coil positions and a substitute diagnosis technique is proposed. In addition, the load torque effect on the detection efficiency of these diagnosis media is discussed and a comparative investigation is performed. The decisive factor of comparison is the fault sensitivity. Experimental results show that spectral analysis of the axial stray flux can be an alternative solution to cover effectiveness limitation of the traditional stator current technique and to substitute the classical vibration practice.

  11. Real time automatic detection of bearing fault in induction machine using kurtogram analysis.

    PubMed

    Tafinine, Farid; Mokrani, Karim

    2012-11-01

    A proposed signal processing technique for incipient real time bearing fault detection based on kurtogram analysis is presented in this paper. The kurtogram is a fourth-order spectral analysis tool introduced for detecting and characterizing non-stationarities in a signal. This technique starts from investigating the resonance signatures over selected frequency bands to extract the representative features. The traditional spectral analysis is not appropriate for non-stationary vibration signal and for real time diagnosis. The performance of the proposed technique is examined by a series of experimental tests corresponding to different bearing conditions. Test results show that this signal processing technique is an effective bearing fault automatic detection method and gives a good basis for an integrated induction machine condition monitor.

  12. Incipient interturn fault diagnosis in induction machines using an analytic wavelet-based optimized Bayesian inference.

    PubMed

    Seshadrinath, Jeevanand; Singh, Bhim; Panigrahi, Bijaya Ketan

    2014-05-01

    Interturn fault diagnosis of induction machines has been discussed using various neural network-based techniques. The main challenge in such methods is the computational complexity due to the huge size of the network, and in pruning a large number of parameters. In this paper, a nearly shift insensitive complex wavelet-based probabilistic neural network (PNN) model, which has only a single parameter to be optimized, is proposed for interturn fault detection. The algorithm constitutes two parts and runs in an iterative way. In the first part, the PNN structure determination has been discussed, which finds out the optimum size of the network using an orthogonal least squares regression algorithm, thereby reducing its size. In the second part, a Bayesian classifier fusion has been recommended as an effective solution for deciding the machine condition. The testing accuracy, sensitivity, and specificity values are highest for the product rule-based fusion scheme, which is obtained under load, supply, and frequency variations. The point of overfitting of PNN is determined, which reduces the size, without compromising the performance. Moreover, a comparative evaluation with traditional discrete wavelet transform-based method is demonstrated for performance evaluation and to appreciate the obtained results.

  13. Commande non lineaire avec optimisation energetique de la machine a induction triphase

    NASA Astrophysics Data System (ADS)

    Fossi Tchaptchet, Marcel Stephan

    This thesis deals with the power efficiency optimization of a variable speed induction motor drives. Optimized performance is realized by adjusting the level of magnetization in the machine load. The loss model was used to analyze control strategies for optimum energy efficiency. Two control strategies were considered using 1.5 kW and 4.5 kW motors. The performance of the first strategy was performed using a vector control where the optimization approach is to determine the optimal flux to be regulated from the losses equations and then find the minimal losses. This optimal flux served set a reference to regulate the flux and then the machine losses, with a classical PI regulator. The second approach uses a non-linear controller to regulate the two outputs: the speed and the mathematical expression of losses. The results obtained give an improvement from 29.73 to 40% with the nonlinear approach and from 15.5% to 36.6% with the linear one.

  14. Multi-objective optimization of the induction machine with minimization of audible electromagnetic noise

    NASA Astrophysics Data System (ADS)

    Le Besnerais, J.; Hecquet, M.; Lanfranchi, V.; Brochet, P.

    2007-08-01

    Induction motors optimal design can involve many variables and objectives, and generally requires to make several trade-offs, especially when including the audible electromagnetic noise criterion beyond the usual performance criteria. Multiobjective optimization techniques based on Pareto optimality are useful to help us finding the most interesting solutions and decide which one(s) to adopt. However, it is not always easy to analyse the Pareto-optimal solutions obtained with such methods, especially when treating more than three objectives, and Pareto fronts may contain more data than we might think. This paper briefly describes an analytical model of the variable-speed squirrel-cage induction machine which computes both its performances and sound power level of electromagnetic origin. The model is then coupled to the Non-dominated Sorting Genetic Algorithm (NSGA-II) in order to perform global optimization with respect to several objectives (e.g. noise level, efficiency and material cost). Finally, an optimization problem is solved and analysed, and some useful visualization tools of the Pareto optimal solutions and their characteristics are presented.

  15. Practical design and operating characteristic analysis of a 10 kW HTS DC induction heating machine

    NASA Astrophysics Data System (ADS)

    Choi, Jongho; Kim, Kwangmin; Park, Minwon; Yu, In-Keun; Kim, Seokho; Sim, Kideok; Kim, Hae-jong

    2014-09-01

    Conventional induction heaters have been in operation in metal and related industries with poor energy efficiencies of only 50-60%. Also, the efficiency of atmosphere furnace, one of the various heating facilities for metal billets, is about 20%. Hence, a high temperature superconducting (HTS) DC induction heating machine to heat a rotating metal billet under uniform magnetic field generated by the 2G HTS magnet with about 80-90% of the system energy efficiency has been researched in this paper. We presented practical design specification, operational characteristics, and temperature distribution on a 10 kW class HTS DC induction heating machine which had been built and tested. The saturated temperature of an HTS no-insulated(NI) coil in the cryostat fabricated with 100 A of the operating current reached 45.9 K and the magnetic field at the centre point between two iron cores measured 0.2 T. The rotating machine for 4.1 kg of the aluminum billet was tested on 1760 rpm of the rated rotating speed. The final temperature of the aluminum billet has risen up to 500 °C for 480 s. The research outcomes are expected to be useful for the design of a large scale HTS DC induction heating machine in industries.

  16. A new self-regulated self-excited single-phase induction generator using a squirrel cage three-phase induction machine

    SciTech Connect

    Fukami, Tadashi; Imamura, Michinori; Kaburaki, Yuichi; Miyamoto, Toshio

    1995-12-31

    A new single-phase capacitor self-excited induction generator with self-regulating feature is presented. The new generator consists of a squirrel cage three-phase induction machine and three capacitors connected in series and parallel with a single phase load. The voltage regulation of this generator is very small due to the effect of the three capacitors. Moreover, since a Y-connected stator winding is employed, the waveform of the output voltage becomes sinusoidal. In this paper the system configuration and the operating principle of the new generator are explained, and the basic characteristics are also investigated by means of a simple analysis and experiments with a laboratory machine.

  17. Designing Multipolar Resonances in Dielectric Metamaterials.

    PubMed

    Butakov, Nikita A; Schuller, Jon A

    2016-12-08

    Dielectric resonators form the building blocks of nano-scale optical antennas and metamaterials. Due to their multipolar resonant response and low intrinsic losses they offer design flexibility and high-efficiency performance. These resonators are typically described in terms of a spherical harmonic decomposition with Mie theory. In experimental realizations however, a departure from spherical symmetry and the use of high-index substrates leads to new features appearing in the multipolar response. To clarify this behavior, we present a systematic experimental and numerical characterization of Silicon disk resonators. We demonstrate that for disk resonators on low-index quartz substrates, the electric and magnetic dipole modes are easily identifiable across a wide range of aspect-ratios, but that higher order peaks cannot be unambiguously associated with any specific multipolar mode. On high-index Silicon substrates, even the fundamental dipole modes do not have a clear association. When arranged into arrays, resonances are shifted and pronounced preferential forward and backward scattering conditions appear, which are not as apparent in individual resonators and may be associated with interference between multipolar modes. These findings present new opportunities for engineering the multipolar scattering response of dielectric optical antennas and metamaterials, and provide a strategy for designing nano-optical components with unique functionalities.

  18. Designing Multipolar Resonances in Dielectric Metamaterials

    PubMed Central

    Butakov, Nikita A.; Schuller, Jon A.

    2016-01-01

    Dielectric resonators form the building blocks of nano-scale optical antennas and metamaterials. Due to their multipolar resonant response and low intrinsic losses they offer design flexibility and high-efficiency performance. These resonators are typically described in terms of a spherical harmonic decomposition with Mie theory. In experimental realizations however, a departure from spherical symmetry and the use of high-index substrates leads to new features appearing in the multipolar response. To clarify this behavior, we present a systematic experimental and numerical characterization of Silicon disk resonators. We demonstrate that for disk resonators on low-index quartz substrates, the electric and magnetic dipole modes are easily identifiable across a wide range of aspect-ratios, but that higher order peaks cannot be unambiguously associated with any specific multipolar mode. On high-index Silicon substrates, even the fundamental dipole modes do not have a clear association. When arranged into arrays, resonances are shifted and pronounced preferential forward and backward scattering conditions appear, which are not as apparent in individual resonators and may be associated with interference between multipolar modes. These findings present new opportunities for engineering the multipolar scattering response of dielectric optical antennas and metamaterials, and provide a strategy for designing nano-optical components with unique functionalities. PMID:27929038

  19. Designing Multipolar Resonances in Dielectric Metamaterials

    NASA Astrophysics Data System (ADS)

    Butakov, Nikita A.; Schuller, Jon A.

    2016-12-01

    Dielectric resonators form the building blocks of nano-scale optical antennas and metamaterials. Due to their multipolar resonant response and low intrinsic losses they offer design flexibility and high-efficiency performance. These resonators are typically described in terms of a spherical harmonic decomposition with Mie theory. In experimental realizations however, a departure from spherical symmetry and the use of high-index substrates leads to new features appearing in the multipolar response. To clarify this behavior, we present a systematic experimental and numerical characterization of Silicon disk resonators. We demonstrate that for disk resonators on low-index quartz substrates, the electric and magnetic dipole modes are easily identifiable across a wide range of aspect-ratios, but that higher order peaks cannot be unambiguously associated with any specific multipolar mode. On high-index Silicon substrates, even the fundamental dipole modes do not have a clear association. When arranged into arrays, resonances are shifted and pronounced preferential forward and backward scattering conditions appear, which are not as apparent in individual resonators and may be associated with interference between multipolar modes. These findings present new opportunities for engineering the multipolar scattering response of dielectric optical antennas and metamaterials, and provide a strategy for designing nano-optical components with unique functionalities.

  20. Performances improvements and torque ripple minimization for VSI fed induction machine with direct control torque.

    PubMed

    Abdelli, R; Rekioua, D; Rekioua, T

    2011-04-01

    This paper describes a torque ripple reduction technique with constant switching frequency for direct torque control (DTC) of an induction motor (IM). This method enables a minimum torque ripple control. In order to obtain a constant switching frequency and hence a torque ripple reduction, we propose a control technique for IM. It consists of controlling directly the electromagnetic torque by using a modulated hysteresis controller. The design methodology is based on space vector modulation (SVM) of electrical machines with digital vector control. MATLAB simulations supported with experimental study are used. The simulation and experimental results of this proposed algorithm show an adequate dynamic to IM; however, the research can be extended to include synchronous motors as well. The implementation of the proposed algorithm is described. It doesn't require any PI controller in the torque control loop. The hardware inverter is controlled digitally using a Texas Instruments TMS320F240 digital signal processor (DSP) with composed C codes for generating the required references. The results obtained from simulation and experiments confirmed the feasibility of the proposed strategy compared to the conventional one.

  1. Induction machine Direct Torque Control system based on fuzzy adaptive control

    NASA Astrophysics Data System (ADS)

    Li, Shi-ping; Yu, Yan; Jiao, Zhen-gang; Gu, Shu-sheng

    2009-07-01

    Direct Torque Control technology is a high-performance communication control method, it uses the space voltage vector method, and then to the inverter switch state control, to obtain high torque dynamic performance. But none of the switching states is able to generate the exact voltage vector to produce the desired changes in torque and flux in most of the switching instances. This causes a high ripple in torque. To solve this problem, a fuzzy implementation of Direct Torque Control of Induction machine is presented here. Error of stator flux, error of motor electromagnetic torque and position of angle of flux are taken as fuzzy variables. In order to further solve nonlinear problem of variation parameters in direct torque control system, the paper proposes a fuzzy parameter PID adaptive control method which is suitable for the direct torque control of an asynchronous motor. The generation of its fuzzy control is obtained by analyzing and optimizing PID control step response and combining expert's experience. For this reason, it carries out fuzzy work to PID regulator of motor speed to achieve to regulate PID parameters. Therefore the control system gets swifter response velocity, stronger robustness and higher precision of velocity control. The computer simulated results verify the validity of this novel method.

  2. Real time PI-backstepping induction machine drive with efficiency optimization.

    PubMed

    Farhani, Fethi; Ben Regaya, Chiheb; Zaafouri, Abderrahmen; Chaari, Abdelkader

    2017-09-01

    This paper describes a robust and efficient speed control of a three phase induction machine (IM) subjected to load disturbances. First, a Multiple-Input Multiple-Output (MIMO) PI-Backstepping controller is proposed for a robust and highly accurate tracking of the mechanical speed and rotor flux. Asymptotic stability of the control scheme is proven by Lyapunov Stability Theory. Second, an active online optimization algorithm is used to optimize the efficiency of the drive system. The efficiency improvement approach consists of adjusting the rotor flux with respect to the load torque in order to minimize total losses in the IM. A dSPACE DS1104 R&D board is used to implement the proposed solution. The experimental results released on 3kW squirrel cage IM, show that the reference speed as well as the rotor flux are rapidly achieved with a fast transient response and without overshoot. A good load disturbances rejection response and IM parameters variation are fairly handled. The improvement of drive system efficiency reaches up to 180% at light load. Copyright © 2017 ISA. Published by Elsevier Ltd. All rights reserved.

  3. Induction machine bearing faults detection based on a multi-dimensional MUSIC algorithm and maximum likelihood estimation.

    PubMed

    Elbouchikhi, Elhoussin; Choqueuse, Vincent; Benbouzid, Mohamed

    2016-07-01

    Condition monitoring of electric drives is of paramount importance since it contributes to enhance the system reliability and availability. Moreover, the knowledge about the fault mode behavior is extremely important in order to improve system protection and fault-tolerant control. Fault detection and diagnosis in squirrel cage induction machines based on motor current signature analysis (MCSA) has been widely investigated. Several high resolution spectral estimation techniques have been developed and used to detect induction machine abnormal operating conditions. This paper focuses on the application of MCSA for the detection of abnormal mechanical conditions that may lead to induction machines failure. In fact, this paper is devoted to the detection of single-point defects in bearings based on parametric spectral estimation. A multi-dimensional MUSIC (MD MUSIC) algorithm has been developed for bearing faults detection based on bearing faults characteristic frequencies. This method has been used to estimate the fundamental frequency and the fault related frequency. Then, an amplitude estimator of the fault characteristic frequencies has been proposed and fault indicator has been derived for fault severity measurement. The proposed bearing faults detection approach is assessed using simulated stator currents data, issued from a coupled electromagnetic circuits approach for air-gap eccentricity emulating bearing faults. Then, experimental data are used for validation purposes.

  4. Electromechanical Interaction in Eccentric-Rotor Cage Induction Machine Equipped with a Self-Bearing Force Actuator

    NASA Astrophysics Data System (ADS)

    Laiho, Antti; Tammi, Kari; Orivuori, Juha; Sinervo, Anssi; Zenger, Kai; Arkkio, Antero

    In this paper, flexural rotor vibration in a two-pole cage induction machine equipped with a built-in force actuator is examined. The built-in force actuator is based on the self-bearing machine technology in which a supplementary winding is placed in the machine for force production. The built-in force actuator enables active vibration control, but also it enables excitation of the machine for purposes of condition monitoring, for instance. A low-order parametric model is derived for the actuator-rotor system. In the model, the arbitrary eccentric rotor motion is coupled with the voltage-flux equations for the supplementary winding and eccentric rotor cage. Furthermore, based on frequency-domain system identification, a control method is examined for compensating synchronous rotor vibration. Experimental results are given for a two-pole cage induction motor. The main contribution of the article is to couple eccentric rotor motion, the built-in force actuator and the mechanical rotor model to obtain a low-order parametric model of the actuator-rotor system which can be applied to control design for rotor vibration suppression.

  5. Digital signal processing control of induction machine`s torque and stator flux utilizing the direct stator flux field orientation method

    SciTech Connect

    Seiz, Julie Burger

    1997-04-01

    This paper presents a review of the Direct Stator Flux Field Orientation control method. This method can be used to control an induction motor`s torque and flux directly and is the application of interest for this thesis. This control method is implemented without the traditional feedback loops and associated hardware. Predictions are made, by mathematical calculations, of the stator voltage vector. The voltage vector is determined twice a switching period. The switching period is fixed throughout the analysis. The three phase inverter duty cycle necessary to control the torque and flux of the induction machine is determined by the voltage space vector Pulse Width Modulation (PWM) technique. Transient performance of either the flux or torque requires an alternate modulation scheme which is also addressed in this thesis. A block diagram of this closed loop system is provided. 22 figs., 7 tabs.

  6. Quantifying human subjective experience and social interaction using the eXperience Induction Machine.

    PubMed

    Bernardet, Ulysses; Väljamäe, Aleksander; Inderbitzin, Martin; Wierenga, Sytse; Mura, Anna; Verschure, Paul F M J

    2011-06-30

    With the advance of novel brain imaging technology more correlations between complex human properties and the neuronal substrate can be assessed. However, thus far, not many well-validated paradigms exist that would allow for a systematic and quantitative exploration of these phenomena. For instance, despite the rapid technological advances in the domain of mixed and virtual reality systems, a fundamental issue remains how we can define and quantify "presence". A standard approach has been to use questionnaires and self-report measures. However, it has been well established that humans' capabilities to access and externalize their internal states are limited. Hence, we have investigated the question whether other less subjective measures can be devised that can corroborate subjective self-reports on presence. In particular, we have developed a quantitative recollection task that assesses the ability of human subjects (N=40) to recollect the factual structure and organization of a structured and fully controlled experience in a human accessible mixed reality space, the eXperience Induction Machine (XIM). In this structured experience - referred to as the "Autodemo"--a virtual guide explains the key elements and properties of XIM while the user is able to freely move around in the space. To evaluate the users' experience and the amount of factual information retained about the Autodemo, we used the ITC-SOPI questionnaire and a recall test specifically designed for the Autodemo. We found significant correlations between spatial presence and engagement factors of ITC-SOPI and recall performance. Moreover we observed an interaction with the participants' gender. Our results show that we can assess correlates of "presence" by focusing on other dependent measures such as those related to memory and performance. Additionally, our work exemplifies how virtual and mixed reality systems provide new ways to address fundamental questions in psychology and cognitive neuroscience

  7. Polarizable multipolar electrostatics for cholesterol

    NASA Astrophysics Data System (ADS)

    Fletcher, Timothy L.; Popelier, Paul L. A.

    2016-08-01

    FFLUX is a novel force field under development for biomolecular modelling, and is based on topological atoms and the machine learning method kriging. Successful kriging models have been obtained for realistic electrostatics of amino acids, small peptides, and some carbohydrates but here, for the first time, we construct kriging models for a sizeable ligand of great importance, which is cholesterol. Cholesterol's mean total (internal) electrostatic energy prediction error amounts to 3.9 kJ mol-1, which pleasingly falls below the threshold of 1 kcal mol-1 often cited for accurate biomolecular modelling. We present a detailed analysis of the error distributions.

  8. Design and Performance Analysis of an Iron Core-based No-Insulation HTS Magnet for HTS DC Induction Heating Machine

    NASA Astrophysics Data System (ADS)

    Choi, Jongho; Kim, Kwangmin; Kim, Sung-Kyu; Kim, Seokho; Sim, Kideok; Park, Minwon; Yu, In-Keun

    An energy efficiency of a high temperature superconducting (HTS) DC induction heating machine is improved up to 80∼90%. The core technology in the machine is to ensure its thermal stability during operation. In this paper, we presented design details and performance analysis results of no insulation HTS magnet with an iron core for an HTS DC induction heating machine. The HTS magnet was simulated by a finite element method and an equivalent circuit analysis. In order to confirm physical performances, the magnet was fabricated and experimented with an iron core as well as without an iron core. The simulated and experimented results were analyzed in detail.

  9. Spherical tensor multipolar electrostatics and smooth particle mesh Ewald summation: a theoretical study.

    PubMed

    Zielinski, François; Popelier, Paul L A

    2014-07-01

    The point-charge approximation, typically used by classical molecular mechanics force-fields, can be overcome by a multipolar expansion. For decades multipole moments were only used in the context of the rigid body approximation but recently it has become possible to combine multipolar electrostatics with molecular flexibility. The program DL_MULTI, which is derived from DL_POLY_2, includes efficient multipolar Ewald functionality up to the hexadecapole moment but the code is restricted to rigid bodies. The incorporation of flexibility into DL_MULTI would cause too large an impact on its architecture whereas the package DL_POLY_4 offers a more attractive and sustainable route to handle multipolar electrostatics. This package inherently handles molecular flexibility, which warrants sufficiently transferable atoms or atoms that are "knowledgeable" about their chemical environment (as made possible by quantum chemical topology and machine learning). DL_MULTI uses the spherical multipole formalism, which is mathematically more involved than the Cartesian one but which is more compact. DL_POLY_4 uses the computationally efficient method of smooth particle mesh Ewald (SPME) summation, which has also been parallellized by others. Therefore, combining the strengths of DL_POLY_4 and DL_MULTI poses the challenge of merging SPME with multipolar electrostatics by spherical multipole. In an effort to recast as clearly as possible the principles behind DL_MULTI, its key equations have been reformulated by the more streamlined route involving the algebra of complex numbers, and some of these equations' peculiarities clarified. This article explores theoretically the repercussions of the merging of SPME with spherical multipole electrostatics (as implemented in DL_MULTI). Difficulties in design and implementation of possible future code are discussed.

  10. Direct Torque Control of a Three-Phase Voltage Source Inverter-Fed Induction Machine

    DTIC Science & Technology

    2013-12-01

    of three-phase induction motor using microcontroller,” S.R.M Engineering College, Tamil Nadu, India, June/July 2006. [5] Texas Instruments Europe...induction motor using microcontroller,” S.R.M Engineering College, Tamil Nadu, India, June/July 2006. [8] C. R. Nave, “Faraday’s law,” Georgia State

  11. A global optimization approach to multi-polarity sentiment analysis.

    PubMed

    Li, Xinmiao; Li, Jing; Wu, Yukeng

    2015-01-01

    Following the rapid development of social media, sentiment analysis has become an important social media mining technique. The performance of automatic sentiment analysis primarily depends on feature selection and sentiment classification. While information gain (IG) and support vector machines (SVM) are two important techniques, few studies have optimized both approaches in sentiment analysis. The effectiveness of applying a global optimization approach to sentiment analysis remains unclear. We propose a global optimization-based sentiment analysis (PSOGO-Senti) approach to improve sentiment analysis with IG for feature selection and SVM as the learning engine. The PSOGO-Senti approach utilizes a particle swarm optimization algorithm to obtain a global optimal combination of feature dimensions and parameters in the SVM. We evaluate the PSOGO-Senti model on two datasets from different fields. The experimental results showed that the PSOGO-Senti model can improve binary and multi-polarity Chinese sentiment analysis. We compared the optimal feature subset selected by PSOGO-Senti with the features in the sentiment dictionary. The results of this comparison indicated that PSOGO-Senti can effectively remove redundant and noisy features and can select a domain-specific feature subset with a higher-explanatory power for a particular sentiment analysis task. The experimental results showed that the PSOGO-Senti approach is effective and robust for sentiment analysis tasks in different domains. By comparing the improvements of two-polarity, three-polarity and five-polarity sentiment analysis results, we found that the five-polarity sentiment analysis delivered the largest improvement. The improvement of the two-polarity sentiment analysis was the smallest. We conclude that the PSOGO-Senti achieves higher improvement for a more complicated sentiment analysis task. We also compared the results of PSOGO-Senti with those of the genetic algorithm (GA) and grid search method. From

  12. Finite Element Analysis in the Estimation of Air-Gap Torque and Surface Temperature of Induction Machine

    NASA Astrophysics Data System (ADS)

    Mr., J. Ravi Kumar; Banakara, Basavaraja, Dr.

    2017-08-01

    This paper presents electromagnetic and thermal behavior of Induction Motor (IM) through the modeling and analysis by applying multiphysics coupled Finite Element Analysis (FEA). Therefore prediction of the magnetic flux, electromagnetic torque, stator and rotor losses and temperature distribution inside an operating electric motor are the most important issues during its design. Prediction and estimation of these parameters allows design engineers to decide capability of the machine for the proposed load, temperature rating and its application for which it is being designed ensuring normal motor operation at rated conditions. In this work, multiphysics coupled electromagnetic – thermal modeling and analysis of induction motor at rated and high frequency has carried out applying Arkkio’s torque method. COMSOL Multiphysics software is used for modeling and finite element analysis of IM. Transient electromagnetic torque, magnetic field distribution, speed-torque characteristics of IM were plotted and studied at different frequencies. This proposed work helps in the design and prediction of accurate performance of induction motor specific to various industrial drive applications. Results obtained are also validated with experimental analysis. The main purpose of this model is to use it as an integral part of the design aiming to system optimization of Variable Speed Drive (VSD) and its components using coupled simulations.

  13. Etude de sensibilite du profil de durete des engrenages traites thermiquement par induction en fonction des parametres machine

    NASA Astrophysics Data System (ADS)

    Barka, Noureddine

    This project involves a study of sensitivity of the hardness profile of cylindrical bars and spur gears heated by induction using finite element models (axisymmetric and 2D) combined with experimental tests. This sensitivity study is considered as the basic step towards the development of prediction models. The study mainly aims at evaluating the effect of material properties and machine parameters on the hardness profile. As the induction heating is very fast, it is reasonable to assume that the material properties are different from those measured under thermodynamic equilibrium conditions. For this reason, the study attempts to measure the effect of variations in material properties on the surface temperature using the axisymmetric model. The results show that the relative magnetic permeability is the property that most significantly influences surface temperatures and the variation of this property has a large effect on the hardness profile. The effects of specific heat and electrical conductivity are rather low, while the thermal conductivity has a negligible effect on the model developed. Moreover, the variation in temperature of austenitizing margins have limited effects on the developed model. Therefore, the use of material properties at thermodynamic equilibrium was sufficient to establish models for predicting trends. Moreover, study of global sensitivity profile of hardness as a function of machine parameters allowed, in the first place, to compare the two cases of heat to medium and high frequency, by applying them to a disc and a gear and determine the effect of the imposed current density and heating time on the hardness profile using the results of the simulations. It appears that the edge effect is smaller in the MF heating case. In addition, the 2D model can confirm that the MF power heat more the tooth root, while the HF power heat the tooth tip region. Finally, the regression models developed were used to estimate surface temperatures and depths

  14. Vibro-acoustic behaviour of an induction machine with stator inter-turn short-circuit

    NASA Astrophysics Data System (ADS)

    Jelassi, Sana; Romary, Raphael; Brudny, Jean-François

    2016-01-01

    This paper focuses on the calculation of noise and vibrations due to electromagnetic forces in rotating electrical machines in faulty conditions. The effects of a stator inter turn short circuit is analysed through an analytical model. Theoretical results give the radial forces and explain the reasons behind the noise and vibrations. They also show how inter-turn-short-circuit is responsible for additional low-mode forces, generating noise and vibrations increase. Experimental measurements are carried out to validate the theoretical results.

  15. Perturbation theory for multipolar discrete fluids.

    PubMed

    Benavides, Ana L; Gámez, Francisco

    2011-10-07

    An analytical expression for the Helmholtz free energy of discrete multipolar potentials as a function of density, temperature, and intermolecular parameters is obtained as an extension of the multipolar square-well perturbation theory [A. L. Benavides, Y. Guevara, and F. del Río, Physica A 202, 420 (1994)]. The presented procedure is suitable for the description of a more general intermolecular potential model taking into account the overlap and dispersion forces through a discrete potential represented by a sequence of square-shoulders and wells, as well as electrostatic interactions. The main advantage of this approach is that since the Helmholtz free energy is given as an explicit expression in terms of the intermolecular parameters characterizing the interaction, the properties of interest can be easily obtained through usual thermodynamic relations. Besides, since a great variety of discretized potentials can be used with this equation of state, its applicability is very vast. By varying the intermolecular parameters, some illustrative cases are considered, and their phase diagrams are tested against available simulation data. It is found that this theoretical approach is able to reproduce qualitatively and quantitatively well the vapor-liquid equilibrium of the chosen potentials with different multipole moment of varied strengths, except in the critical region. © 2011 American Institute of Physics

  16. Perturbation theory for multipolar discrete fluids

    NASA Astrophysics Data System (ADS)

    Benavides, Ana L.; Gámez, Francisco

    2011-10-01

    An analytical expression for the Helmholtz free energy of discrete multipolar potentials as a function of density, temperature, and intermolecular parameters is obtained as an extension of the multipolar square-well perturbation theory [A. L. Benavides, Y. Guevara, and F. del Río, Physica A 202, 420 (1994), 10.1016/0378-4371(94)90469-3]. The presented procedure is suitable for the description of a more general intermolecular potential model taking into account the overlap and dispersion forces through a discrete potential represented by a sequence of square-shoulders and wells, as well as electrostatic interactions. The main advantage of this approach is that since the Helmholtz free energy is given as an explicit expression in terms of the intermolecular parameters characterizing the interaction, the properties of interest can be easily obtained through usual thermodynamic relations. Besides, since a great variety of discretized potentials can be used with this equation of state, its applicability is very vast. By varying the intermolecular parameters, some illustrative cases are considered, and their phase diagrams are tested against available simulation data. It is found that this theoretical approach is able to reproduce qualitatively and quantitatively well the vapor-liquid equilibrium of the chosen potentials with different multipole moment of varied strengths, except in the critical region.

  17. The eXperience Induction Machine: A New Paradigm for Mixed-Reality Interaction Design and Psychological Experimentation

    NASA Astrophysics Data System (ADS)

    Bernardet, Ulysses; Bermúdez I Badia, Sergi; Duff, Armin; Inderbitzin, Martin; Le Groux, Sylvain; Manzolli, Jônatas; Mathews, Zenon; Mura, Anna; Väljamäe, Aleksander; Verschure, Paul F. M. J.

    The eXperience Induction Machine (XIM) is one of the most advanced mixed-reality spaces available today. XIM is an immersive space that consists of physical sensors and effectors and which is conceptualized as a general-purpose infrastructure for research in the field of psychology and human-artifact interaction. In this chapter, we set out the epistemological rational behind XIM by putting the installation in the context of psychological research. The design and implementation of XIM are based on principles and technologies of neuromorphic control. We give a detailed description of the hardware infrastructure and software architecture, including the logic of the overall behavioral control. To illustrate the approach toward psychological experimentation, we discuss a number of practical applications of XIM. These include the so-called, persistent virtual community, the application in the research of the relationship between human experience and multi-modal stimulation, and an investigation of a mixed-reality social interaction paradigm.

  18. Support vector machine based decision for mechanical fault condition monitoring in induction motor using an advanced Hilbert-Park transform.

    PubMed

    Ben Salem, Samira; Bacha, Khmais; Chaari, Abdelkader

    2012-09-01

    In this work we suggest an original fault signature based on an improved combination of Hilbert and Park transforms. Starting from this combination we can create two fault signatures: Hilbert modulus current space vector (HMCSV) and Hilbert phase current space vector (HPCSV). These two fault signatures are subsequently analysed using the classical fast Fourier transform (FFT). The effects of mechanical faults on the HMCSV and HPCSV spectrums are described, and the related frequencies are determined. The magnitudes of spectral components, relative to the studied faults (air-gap eccentricity and outer raceway ball bearing defect), are extracted in order to develop the input vector necessary for learning and testing the support vector machine with an aim of classifying automatically the various states of the induction motor.

  19. Effects of stator and rotor core ovality on induction machine behavior

    SciTech Connect

    Salon, S.J.; Burow, D.W.; DeBortoli, M.J.; Slavik, C.J.

    1996-09-01

    Asymmetries in the air gap of induction motors produce additional harmonics in the flux density and force waves. A complete transient finite element model analyzes the harmonics produced from two possible asymmetries, a stator core ovality and a rotor ovality. The analysis of the air gap flux density and magnetic force waves determined by the finite element model shows unique harmonic frequencies due to the ovality of the air gap.

  20. Effects of stator and rotor core ovality on induction machine behavior

    SciTech Connect

    Salon, S.J.; Burow, D.W.

    1995-07-01

    Asymmetries in the air gap of induction motors produce additional harmonics in the flux density and force waves. A complete transient finite element model analyzes the harmonics produced from two possible asymmetries, a stator core ovality and a rotor ovality. The analysis of the air gap flux density and magnetic force waves determined by the finite element model shows unique harmonic frequencies due to the ovality of the air gap.

  1. Voltage-Source Series Resonant Zero Current Soft Switching High-Frequency Inverter with PDM Scheme for Induction Heating Roller in Copy Machine

    NASA Astrophysics Data System (ADS)

    Feng, Yuelu; Nakaoka, Mutsuo

    This paper presents a voltage source half bridge series load resonant ZCS-PDM high frequency inverter using IGBT power module for the induction-heating roller in copy machines. The steady-state operating principle and unique features of this high frequency inverter with two ZCS-assisted inductive snubbers in series with the active power switch are presented, which can achieve stable zero current soft commutation under pulse density modulated power regulation scheme. The experimental results of cost effective ZCS-PDM inverter treated here are evaluated on basis of computer simulation ones and discussed for the induction-heating roller from a practice point of view

  2. Detection of stator winding faults in induction machines using flux and vibration analysis

    NASA Astrophysics Data System (ADS)

    Lamim Filho, P. C. M.; Pederiva, R.; Brito, J. N.

    2014-01-01

    This work aims at presenting the detection and diagnosis of electrical faults in the stator winding of three-phase induction motors using magnetic flux and vibration analysis techniques. A relationship was established between the main electrical faults (inter-turn short circuits and unbalanced voltage supplies) and the signals of magnetic flux and vibration, in order to identify the characteristic frequencies of those faults. The experimental results showed the efficiency of the conjugation of these techniques for detection, diagnosis and monitoring tasks. The results were undoubtedly impressive and can be adapted and used in real predictive maintenance programs in industries.

  3. A Global Optimization Approach to Multi-Polarity Sentiment Analysis

    PubMed Central

    Li, Xinmiao; Li, Jing; Wu, Yukeng

    2015-01-01

    Following the rapid development of social media, sentiment analysis has become an important social media mining technique. The performance of automatic sentiment analysis primarily depends on feature selection and sentiment classification. While information gain (IG) and support vector machines (SVM) are two important techniques, few studies have optimized both approaches in sentiment analysis. The effectiveness of applying a global optimization approach to sentiment analysis remains unclear. We propose a global optimization-based sentiment analysis (PSOGO-Senti) approach to improve sentiment analysis with IG for feature selection and SVM as the learning engine. The PSOGO-Senti approach utilizes a particle swarm optimization algorithm to obtain a global optimal combination of feature dimensions and parameters in the SVM. We evaluate the PSOGO-Senti model on two datasets from different fields. The experimental results showed that the PSOGO-Senti model can improve binary and multi-polarity Chinese sentiment analysis. We compared the optimal feature subset selected by PSOGO-Senti with the features in the sentiment dictionary. The results of this comparison indicated that PSOGO-Senti can effectively remove redundant and noisy features and can select a domain-specific feature subset with a higher-explanatory power for a particular sentiment analysis task. The experimental results showed that the PSOGO-Senti approach is effective and robust for sentiment analysis tasks in different domains. By comparing the improvements of two-polarity, three-polarity and five-polarity sentiment analysis results, we found that the five-polarity sentiment analysis delivered the largest improvement. The improvement of the two-polarity sentiment analysis was the smallest. We conclude that the PSOGO-Senti achieves higher improvement for a more complicated sentiment analysis task. We also compared the results of PSOGO-Senti with those of the genetic algorithm (GA) and grid search method. From

  4. Arbitrary order permanent Cartesian multipolar electrostatic interactions

    NASA Astrophysics Data System (ADS)

    Boateng, H. A.; Todorov, I. T.

    2015-01-01

    Recently, there has been a concerted effort to implement advanced classical potential energy surfaces by adding higher order multipoles to fixed point charge electrostatics in a bid to increase the accuracy of simulations of condensed phase systems. One major hurdle is the unwieldy nature of the expressions which in part has limited developers mostly to including only dipoles and quadrupoles. In this paper, we present a generalization of the Cartesian formulation of electrostatic multipolar interactions that enables the specification of an arbitrary order of multipoles. Specifically, we derive formulas for arbitrary order implementation of the particle mesh Ewald method and give a closed form formula for the stress tensor in the reciprocal space. In addition, we provide recurrence relations for common electrostatic potentials employed in molecular simulations, which allows for the generalization to arbitrary order and guarantees a computational cost that scales as O(p3) for Cartesian multipole interactions of order p.

  5. Forest discrimination with multipolarization imaging radar

    NASA Technical Reports Server (NTRS)

    Ford, J. P.; Wickland, D. E.

    1985-01-01

    The relations between polarization signatures and biophysical characteristics through a range of different forest environments were investigated using airborne synthetic-aperture (SAR) images acquired at L-band on March 1, 1984 in South Carolina. SAR data acquired in four linear polarization states with 10-m spatial resolution were encoded as color composite images and compared to US Forest Service forest stand data. The most useful correlative forest data were stand basal area, forest age, site condition index, and forest management type. It is found that the multipolarization images discriminate variation in tree density or difference in the amount of understory, but no evidence has been found for discrimination between evergreen and deciduous forest types.

  6. Forest discrimination with multipolarization imaging radar

    NASA Technical Reports Server (NTRS)

    Ford, J. P.; Wickland, D. E.

    1985-01-01

    The use of radar polarization diversity for discriminating forest canopy variables on airborne synthetic-aperture radar (SAR) images is evaluated. SAR images were acquired at L-Band (24.6 cm) simultaneously in four linear polarization states (HH, HV, VH, and VV) in South Carolina on March 1, 1984. In order to relate the polarization signatures to biophysical properties, false-color composite images were compared to maps of forest stands in the timber compartment. In decreasing order, the most useful correlative forest data are stand basal area, forest age, site condition index, and forest management type. It is found that multipolarization images discriminate variation in tree density and difference in the amount of understory, but do not discriminate between evergreen and deciduous forest types.

  7. Brazed Diamond Micropowder Bur Fabricated by Supersonic Frequency Induction Heating for Precision Machining

    NASA Astrophysics Data System (ADS)

    Ma, Bojiang; Lou, Jianpeng; Pang, Qian

    2014-04-01

    The common brazed diamond micropowder bur fabricated in a vacuum furnace produces an even brazing alloy surface. The small brazed diamond grits show low outcropping from the brazing alloy surface, and the chip space between them is small. The bur shows a low grinding efficiency and poor heat dissipation. In this study, a brazed diamond micropowder bur was fabricated by supersonic frequency induction heating. The method afforded a fluctuant surface on the brazing alloy. The brazed diamond grits with an outcropping height distributed uniformly on the fluctuant surface. The fluctuant surface showed a certain chip space. These characteristics of the tool increased the grinding efficiency and decreased the temperature of the grinding arc area. The roughness R a of the ceramic tile surface trimmed by the tool cylinder was between 0.09 and 0.12 μm. In the first 90 min, the decrease in the weight of the ceramic tile ground by the tool cylinder was higher than that ground by the tool fabricated in a vacuum furnace. When the ceramic tile was cylindrically ground, the temperature of the grinding arc area measured using a thermocouple remained below 70 °C.

  8. MULTIPOLAR PLANETARY NEBULAE: NOT AS GEOMETRICALLY DIVERSIFIED AS THOUGHT

    SciTech Connect

    Chong, S.-N.; Imai, H.; Chibueze, J.; Kwok, Sun; Tafoya, D. E-mail: sunkwok@hku.hk

    2012-12-01

    Planetary nebulae (PNe) have diverse morphological shapes, including point-symmetric and multipolar structures. Many PNe also have complicated internal structures such as tori, lobes, knots, and ansae. A complete accounting of all the morphological structures through physical models is difficult. A first step toward such an understanding is to derive the true three-dimensional structure of the nebulae. In this paper, we show that a multipolar nebula with three pairs of lobes can explain many such features, if orientation and sensitivity effects are taken into account. Using only six parameters-the inclination and position angles of each pair-we are able to simulate the observed images of 20 PNe with complex structures. We suggest that multipolar structure is an intrinsic structure of PNe and the statistics of multipolar PNe have been severely underestimated in the past.

  9. Geological applications of multipolarization SAR data

    NASA Technical Reports Server (NTRS)

    Evans, Diane L.

    1986-01-01

    Spaceborne Synthetic Aperture Radar (SAR) data acquired by SEASAT and the Shuttle Imaging Radar (SIR-A/B) operating at L-band with HH polarization were found to be useful in conjunction with other sensors for lithologic discrimination in arid environments with limited vegetation cover. In order to assess the utility of more advanced sensors for geologic research and define the unique contributions each sensor makes, remote sensing data were collected over the Deadman Butte area of the Wind River Basin, Wyoming. The Wind River Basin is an asymmetric sedimentary basin in central Wyoming created during the early Eocene Laramide orogeny. The stratigraphic section of the Deadman Butte study area, which was measured by Woodward is made up of Paleozoic and Mesozoic marine shales, siltstones, limestones, and sandstones. Sensor systems included LANDSAT 4 Thematic Mapper (TM), Thermal Infrared Multispectral Scanner (TIMS) and the Multipolarization, L-band airborne SAR, a prototype for the next Shuttle Imaging Radar (SIR-C). Sensor parameters are given.

  10. Thermal protection performance of magnetohydrodynamic heat shield system based on multipolar magnetic field

    NASA Astrophysics Data System (ADS)

    Kai, Li; Jun, Liu; Weiqiang, Liu

    2017-07-01

    In order to cover the shortage of dipole magnetic field in the magnetohydrodynamic(MHD) heat shield system, physical model of a multipolar magnetic field with central and peripheral solenoids is constructed. By employing the governing equations of three dimensional thermochemical nonequilibrium flow with electromagnetic source terms based on the low magneto-Reynolds assumption, the flow control performance of the dipole and multipolar magnetic fields are numerically simulated. To make the results comparable, two groups of cases are designed by first assuming equal stagnation magnetic induction strength and secondly assuming equal ampere-turns. Results show that, the five-magnet system, whose central polar orientation is the same with the peripheral ones, have stronger work capability and better shock control and thermal protection performance. Moreover, the five-solenoid systems are the best when the ampere-turns of the central solenoid are twice and fourth of the peripheral ones under those two circumstances respectively. Compared with the dipole magnetic field, the stagnation non-catalytic heat fluxes are decreased by a factor of 47.5% and 34.0% respectively.

  11. The multipolar stage and disruptions in neuronal migration.

    PubMed

    LoTurco, Joseph J; Bai, Jilin

    2006-07-01

    The genetic basis is now known for several disorders of neuronal migration in the developing cerebral cortex. Identification of the cellular processes mediated by the implicated genes is revealing crucial stages of neuronal migration and has the potential to reveal common cellular causes of neuronal migration disorders. We hypothesize that a newly recognized morphological stage of neuronal migration, the multipolar stage, is vulnerable and is disrupted in several disorders of neocortical development. The multipolar stage occurs as bipolar progenitor cells become radially migrating neurons. Several studies using in utero electroporation and RNAi have revealed that transition out of the multipolar stage depends on the function of filamin A, LIS1 and DCX. Mutations in the genes encoding these proteins in humans cause distinct neuronal migration disorders, including periventricular nodular heterotopia, subcortical band heterotopia and lissencephaly. The multipolar stage therefore seems to be a critical point of migration control and a vulnerable target for disruption of neocortical development. This review is part of the INMED/TINS special issue "Nature and nurture in brain development and neurological disorders", based on presentations at the annual INMED/TINS symposium (http://inmednet.com/).

  12. Excitation of dark multipolar plasmonic resonances at terahertz frequencies

    PubMed Central

    Chen, Lin; Wei, YuMing; Zang, XiaoFei; Zhu, YiMing; Zhuang, SongLin

    2016-01-01

    We experimentally observe the excitation of dark multipolar spoof localized surface plasmon resonances in a hybrid structure consisting of a corrugated metallic disk coupled with a C-shaped dipole resonator. The uncoupled corrugated metallic disk only supports a dipolar resonance in the transmission spectrum due to perfect symmetry of the structure. However, the dark multipolar spoof localized surface plasmon resonances emerge when coupled with a bright C-shaped resonator which is placed in the vicinity of the corrugated metallic disk. These excited multipolar resonances show minimum influence on the coupling distance between the C-shaped resonator and corrugated metallic disk. The resonance frequencies of the radiative modes are controlled by varying the angle of the C-shaped resonator and the inner disk radius, both of which play dominant roles in the excitation of the spoof localized surface plasmons. Observation of such a transition from the dark to radiative nature of multipolar spoof localized plasmon resonances would find potential applications in terahertz based resonant plasmonic and metamaterial devices. PMID:26903382

  13. Strategies for Business Schools in a Multi-Polar World

    ERIC Educational Resources Information Center

    Dameron, Stephanie; Durand, Thomas

    2013-01-01

    Purpose: The purpose of this paper is to examine the contours of the emerging business education and institutions in a multi-polar world and to identify the causes of the strategic convergence of management education, to explore the limitations of the dominant models of management education and to propose a range of strategic alternatives for…

  14. Strategies for Business Schools in a Multi-Polar World

    ERIC Educational Resources Information Center

    Dameron, Stephanie; Durand, Thomas

    2013-01-01

    Purpose: The purpose of this paper is to examine the contours of the emerging business education and institutions in a multi-polar world and to identify the causes of the strategic convergence of management education, to explore the limitations of the dominant models of management education and to propose a range of strategic alternatives for…

  15. Excitation of dark multipolar plasmonic resonances at terahertz frequencies

    NASA Astrophysics Data System (ADS)

    Chen, Lin; Wei, Yuming; Zang, Xiaofei; Zhu, Yiming; Zhuang, Songlin

    2016-02-01

    We experimentally observe the excitation of dark multipolar spoof localized surface plasmon resonances in a hybrid structure consisting of a corrugated metallic disk coupled with a C-shaped dipole resonator. The uncoupled corrugated metallic disk only supports a dipolar resonance in the transmission spectrum due to perfect symmetry of the structure. However, the dark multipolar spoof localized surface plasmon resonances emerge when coupled with a bright C-shaped resonator which is placed in the vicinity of the corrugated metallic disk. These excited multipolar resonances show minimum influence on the coupling distance between the C-shaped resonator and corrugated metallic disk. The resonance frequencies of the radiative modes are controlled by varying the angle of the C-shaped resonator and the inner disk radius, both of which play dominant roles in the excitation of the spoof localized surface plasmons. Observation of such a transition from the dark to radiative nature of multipolar spoof localized plasmon resonances would find potential applications in terahertz based resonant plasmonic and metamaterial devices.

  16. Radiofrequency ablation of hepatocellular carcinoma: Mono or multipolar?

    PubMed

    Cartier, Victoire; Boursier, Jérôme; Lebigot, Jérôme; Oberti, Frédéric; Fouchard-Hubert, Isabelle; Aubé, Christophe

    2016-03-01

    Thermo-ablation by radiofrequency is recognized as a curative treatment for early-stage hepatocellular carcinoma. However, local recurrence may occur because of incomplete peripheral tumor destruction. Multipolar radiofrequency has been developed to increase the size of the maximal ablation zone. We aimed to compare the efficacy of monopolar and multipolar radiofrequency for the treatment of hepatocellular carcinoma and determine factors predicting failure. A total of 171 consecutive patients with 214 hepatocellular carcinomas were retrospectively included. One hundred fifty-eight tumors were treated with an expandable monopolar electrode and 56 with a multipolar technique using several linear bipolar electrodes. Imaging studies at 6 weeks after treatment, then every 3 months, assessed local effectiveness. Radiofrequency failure was defined as persistent residual tumor after two sessions (primary radiofrequency failure) or local tumor recurrence during follow-up. This study received institutional review board approval (number 2014/77). Imaging showed complete tumor ablation in 207 of 214 lesions after the first session of radiofrequency. After a second session, only two cases of residual viable tumor were observed. During follow-up, there were 46 local tumor recurrences. Thus, radiofrequency failure occurred in 48/214 (22.4%) cases. By multivariate analysis, technique (P < 0.001) and tumor size (P = 0.023) were independent predictors of radiofrequency failure. Failure rate was lower with the multipolar technique for tumors < 25 mm (P = 0.023) and for tumors between 25 and 45 mm (P = 0.082). There was no difference for tumors ≥ 45 mm (P = 0.552). Compared to monopolar radiofrequency, multipolar radiofrequency improves tumor ablation with a subsequent lower rate of local tumor recurrence. © 2015 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

  17. The emerging multi-polar world and China's grand game

    SciTech Connect

    Gupta, Rajan

    2011-01-19

    This talk outlines a scenario describing an emerging multipolar world that is aligned with geographical regions. The stability and security of this multipolar world is examined with respect to demographics, trade (economics), resource constraints, and development. In particular I focus on Asia which has two large countries, China and India, competing for resources and markets and examine the emerging regional relations, opportunities and threats. These relationships must overcome many hurdles - the Subcontinent is in a weak position politically and strategically and faces many threats, and China's growing power could help stabilize it or create new threats. Since the fate of 1.5 billion (2.4 billion by 2050) people depends on how the Subcontinent evolves, this talk is meant to initiates a discussion of what China and India can do to help the region develop and stabilize.

  18. Multipolar radiation of quantum emitters with nanowire optical antennas

    PubMed Central

    Curto, Alberto G.; Taminiau, Tim H.; Volpe, Giorgio; Kreuzer, Mark P.; Quidant, Romain; van Hulst, Niek F.

    2013-01-01

    Multipolar transitions other than electric dipoles are generally too weak to be observed at optical frequencies in single quantum emitters. For example, fluorescent molecules and quantum dots have dimensions much smaller than the wavelength of light and therefore emit predominantly as electric dipoles. Here we demonstrate controlled emission of a quantum dot into multipolar radiation through selective coupling to a linear nanowire antenna. The antenna resonance tailors the interaction of the quantum dot with light, effectively creating a hybrid nanoscale source beyond the simple Hertz dipole. Our findings establish a basis for the controlled driving of fundamental modes in nanoantennas and metamaterials, for the understanding of the coupling of quantum emitters to nanophotonic devices such as waveguides and nanolasers, and for the development of innovative quantum nano-optics components with properties not found in nature. PMID:23612291

  19. From dipolar to multipolar interactions between ultracold Feshbach molecules

    NASA Astrophysics Data System (ADS)

    Quéméner, Goulven; Lepers, Maxence; Luc-Koenig, Eliane; Dulieu, Olivier

    2016-05-01

    Using the multipolar expansion of electrostatic and magnetostatic potential energies, we characterize the long-range interactions between two weakly-bound diatomic molecules, taking as an example the paramagnetic Er2 Feshbach molecules which were produced recently. The interaction between atomic magnetic dipoles gives rise to the usual R-3 leading term of the multipolar expansion, where R is the intermolecular distance. We show that additional terms scaling as R-5, R-7 and so on also appear, which are strongly anisotropic with respect to the orientation of the molecules. These terms can be seen as effective molecular multipole moments reflecting the spatial extension of the molecules which is non-negligible compared to R. We acknowledge the financial support of the COPOMOL project (ANR-13-IS04-0004) from Agence Nationale de la Recherche.

  20. Mapping diverse forest cover with multipolarization airborne radar

    NASA Technical Reports Server (NTRS)

    Ford, J. P.; Wickland, D. E.; Sharitz, R. R.

    1985-01-01

    Imaging radar backscatter in continuously forested areas contains information about the forest canopy; it also contains data about topography, landforms, and terrain texture. For purposes of radar image interpretation and geologic mapping researchers were interested in identifying and separating forest canopy effects from geologic or geomorphic effects on radar images. The objectives of this investigation was to evaluate forest canopy variables in multipolarization radar images under conditions where geologic and topographic variables are at a minimum. A subsidiary objective was to compare the discriminatory capabilities of the radar images with corresponding optical images of similar spatial resolution. It appears that the multipolarization images discriminate variation in tree density, but no evidence was found for discrimination between evergreen and deciduous forest types.

  1. Structural and functional classes of multipolar cells in the ventral cochlear nucleus.

    PubMed

    Doucet, John R; Ryugo, David K

    2006-04-01

    Multipolar cells in the ventral cochlear nucleus (VCN) are a structurally and functionally diverse group of projection neurons. Understanding their role in the ascending pathway involves partitioning multipolar cells into distinct populations and determining where in the brain each sends its coded messages. In this study, we used retrograde labeling techniques in rats to identify multipolar neurons that project their axons to the ipsilateral dorsal cochlear nucleus (DCN), the contralateral CN, or both structures. Three rats received injections of biotinylated dextran amine in the ipsilateral DCN and diamidino yellow in the contralateral CN. Several radiate multipolar neurons (defined by their axonal projections to the ipsilateral DCN and their dendrites that traverse VCN isofrequency sheets) were double-labeled but over 70% were not. This result suggests two distinct populations: (1) radiate-commissural (RC) multipolar cells that project to the ipsilateral DCN and the contralateral CN, and (2) radiate multipolar cells that project exclusively (in this context) to the ipsilateral DCN. In a different group of animals, we retrogradely labeled multipolar neurons that project their axons to the contralateral CN and measured the size of their cell bodies. The mean size of this population (266 +/- 156 microm2) was significantly smaller than those of RC-multipolar cells (418 +/- 140 microm2). We conclude that the CN commissural pathway is composed of at least two components: (1) RC multipolar cells and (2) commissural multipolar cells that are small- and medium-sized neurons that project exclusively (in this context) to the contralateral CN. These results identify separate structural groups of multipolar cells that may correspond to physiological unit types described in the literature. They also provide protocols for isolating and studying different populations of multipolar cells to determine the neural mechanisms that govern their responses to sound.

  2. Multipolar modes in dielectric disk resonator for wireless power transfer

    NASA Astrophysics Data System (ADS)

    Song, Mingzhao; Belov, Pavel; Kapitanova, Polina

    2017-09-01

    We demonstrate a magnetic resonant WPT system based on dielectric disk resonators and investigated the WPT efficiency as a function of separation. It has been demonstrated that the power transfer can be achieved at different multipolar modes. The numerical study shows that the highest WPT efficiency of 99% can be obtained for the MQ mode in an ideal case. However, the efficiency of MQ mode decays much faster than the MD mode which suggests that a trade-off has to be made in the practical WPT system design.

  3. Lithologic mapping in a sedimentary environment using multipolarization SAR images

    NASA Technical Reports Server (NTRS)

    Evans, D. L.; Schenck, L. R.

    1985-01-01

    Multipolarization Synthetic Aperture Radar (SAR) data from the NASA/JPL aircraft SAR were used in conjunction with LANDSAT Thematic Mapper (TM), Thermal Infrared Multispectral Scanner (TIMS), and Airborne Imaging Spectrometer (AIS) data as part of a three-year research program to evaluate the utility of remote sensing measurements for analysis of sedimentary basins. The purpose of this research effort is to construct stratigraphic columns, map variations in the lithology, geometry, and structure of sedimentary rocks in the Wind River/Bighorn Basin area, Wyoming, and to integrate remote sensing data with conventional rain models of basin formation and evolution.

  4. The Role of Angular Momentum in the Construction of Electromagnetic Multipolar Fields

    ERIC Educational Resources Information Center

    Tischler, Nora; Zambrana-Puyalto, Xavier; Molina-Terriza, Gabriel

    2012-01-01

    Multipolar solutions of Maxwell's equations are used in many practical applications and are essential for the understanding of light-matter interactions at the fundamental level. Unlike the set of plane wave solutions of electromagnetic fields, the multipolar solutions do not share a standard derivation or notation. As a result, expressions…

  5. Molecules and mechanisms that regulate multipolar migration in the intermediate zone.

    PubMed

    Cooper, Jonathan A

    2014-01-01

    Most neurons migrate with an elongated, "bipolar" morphology, extending a long leading process that explores the environment. However, when immature projection neurons enter the intermediate zone (IZ) of the neocortex they become "multipolar". Multipolar cells extend and retract cytoplasmic processes in different directions and move erratically-sideways, up and down. Multipolar cells extend axons while they are in the lower half of the IZ. Remarkably, the cells then resume radial migration: they reorient their centrosome and Golgi apparatus towards the pia, transform back to bipolar morphology, and commence locomotion along radial glia (RG) fibers. This reorientation implies the existence of directional signals in the IZ that are ignored during the multipolar stage but sensed after axonogenesis. In vivo genetic manipulation has implicated a variety of candidate directional signals, cell surface receptors, and signaling pathways, that may be involved in polarizing multipolar cells and stabilizing a pia-directed leading process for radial migration. Other signals are implicated in starting multipolar migration and triggering axon outgrowth. Here we review the molecules and mechanisms that regulate multipolar migration, and also discuss how multipolar migration affects the orderly arrangement of neurons in layers and columns in the developing neocortex.

  6. The Role of Angular Momentum in the Construction of Electromagnetic Multipolar Fields

    ERIC Educational Resources Information Center

    Tischler, Nora; Zambrana-Puyalto, Xavier; Molina-Terriza, Gabriel

    2012-01-01

    Multipolar solutions of Maxwell's equations are used in many practical applications and are essential for the understanding of light-matter interactions at the fundamental level. Unlike the set of plane wave solutions of electromagnetic fields, the multipolar solutions do not share a standard derivation or notation. As a result, expressions…

  7. Age-dating volcanic and alluvial surfaces with multipolarization data

    NASA Technical Reports Server (NTRS)

    Farr, T. G.

    1985-01-01

    A false-color multipolarization version of one of the images of Owens Valley area acquired by the JPL Synthetic Aperture Radar (SAR) is given. A geologic map of the alluvial fans there (Gillespie, 1982) is also given for comparison. In general, brightness in the multipolarization images can be seen to be inversely proportional to the age of the surfaces. A more detailed investigation of the relationship between backscatter and age of the surfaces was undertaken with calibrated aircraft SAR data. The quantitative relationship between backscatter coefficient and age for the three polarizations is shown. The straight lines connecting the measured data points imply a steady-state process, although the process or processes leading to this relationship may have operated at rates that varied with climate fluctuations, such as the glacial ages. It is expected that the relationship between radar brightness and age is a consistent one, and that with the wider availability of calibrated radar backscatter data, these relationships can be less well-known areas. The effect of variable such as past climate fluctuations, tectonic disturbance, and rock type must be understood before extension beyond the Mojave Desert region can be attempted.

  8. Anatomy of the Binary Black Hole Recoil: A Multipolar Analysis

    NASA Technical Reports Server (NTRS)

    Schnittman, Jeremy; Buonanno, Alessandra; vanMeter, James R.; Baker, John G.; Boggs, William D.; Centrella, Joan; Kelly, Bernard J.; McWilliams, Sean T.

    2007-01-01

    We present a multipolar analysis of the recoil velocity computed in recent numerical simulations of binary black hole coalescence, for both unequal masses and non-zero, non-precessing spins. We show that multipole moments up to and including 1 = 4 are sufficient to accurately reproduce the final recoil velocity (= 98%) and that only a few dominant modes contribute significantly to it (2 95%). We describe how the relative amplitude, and more importantly, the relative phase, of these few modes control the way in which the recoil builds up throughout the inspiral, merger, and ring-down phases. We also find that the numerical results can be reproduced, to a high level of accuracy, by an effective Newtonian formula for the multipole moments obtained by replacing in the Newtonian formula the radial separation with an effective radius computed from the numerical data. Beyond the merger, the numerical results are reproduced by a superposition of three Kerr quasi-normal modes. Analytic formulae, obtained by expressing the multipole moments in terms of the fundamental QNMs of a Kerr BH, are able to explain the onset and amount of '.anti-kick" for each of the simulations. Lastly, we apply this multipolar analysis to understand the remarkable difference between the amplitudes of planar and non-planar kicks for equal-mass spinning black holes.

  9. Transverse multipolar light-matter couplings in evanescent waves

    NASA Astrophysics Data System (ADS)

    Fernandez-Corbaton, Ivan; Zambrana-Puyalto, Xavier; Bonod, Nicolas; Rockstuhl, Carsten

    2016-11-01

    We present an approach to study the interaction between matter and evanescent fields. The approach is based on the decomposition of evanescent plane waves into multipoles of well-defined angular-momentum transverse to both decay and propagation directions. We use the approach to identify the origin of the recently observed directional coupling of emitters into guided modes, and of the opposite Zeeman state excitation of atoms near a fiber. We explain how to rigorously quantify both effects and show that the directionality and the difference in excitation rates grow exponentially with the multipolar order of the light-matter interaction. We also use the approach to study and maximize the transverse torque exerted by an evanescent plane wave onto a given spherical absorbing particle. All the obtained physical insights can be traced back to the two main features of the decomposition of evanescent plane waves into transverse multipolar modes: A polarization independent exponential dominance of modes with large transverse angular momentum, and a polarization-controlled parity selection rule.

  10. Comparative investigation of vibration and current monitoring for prediction of mechanical and electrical faults in induction motor based on multiclass-support vector machine algorithms

    NASA Astrophysics Data System (ADS)

    Gangsar, Purushottam; Tiwari, Rajiv

    2017-09-01

    This paper presents an investigation of vibration and current monitoring for effective fault prediction in induction motor (IM) by using multiclass support vector machine (MSVM) algorithms. Failures of IM may occur due to propagation of a mechanical or electrical fault. Hence, for timely detection of these faults, the vibration as well as current signals was acquired after multiple experiments of varying speeds and external torques from an experimental test rig. Here, total ten different fault conditions that frequently encountered in IM (four mechanical fault, five electrical fault conditions and one no defect condition) have been considered. In the case of stator winding fault, and phase unbalance and single phasing fault, different level of severity were also considered for the prediction. In this study, the identification has been performed of the mechanical and electrical faults, individually and collectively. Fault predictions have been performed using vibration signal alone, current signal alone and vibration-current signal concurrently. The one-versus-one MSVM has been trained at various operating conditions of IM using the radial basis function (RBF) kernel and tested for same conditions, which gives the result in the form of percentage fault prediction. The prediction performance is investigated for the wide range of RBF kernel parameter, i.e. gamma, and selected the best result for one optimal value of gamma for each case. Fault predictions has been performed and investigated for the wide range of operational speeds of the IM as well as external torques on the IM.

  11. Molecules and mechanisms that regulate multipolar migration in the intermediate zone

    PubMed Central

    Cooper, Jonathan A.

    2014-01-01

    Most neurons migrate with an elongated, “bipolar” morphology, extending a long leading process that explores the environment. However, when immature projection neurons enter the intermediate zone (IZ) of the neocortex they become “multipolar”. Multipolar cells extend and retract cytoplasmic processes in different directions and move erratically—sideways, up and down. Multipolar cells extend axons while they are in the lower half of the IZ. Remarkably, the cells then resume radial migration: they reorient their centrosome and Golgi apparatus towards the pia, transform back to bipolar morphology, and commence locomotion along radial glia (RG) fibers. This reorientation implies the existence of directional signals in the IZ that are ignored during the multipolar stage but sensed after axonogenesis. In vivo genetic manipulation has implicated a variety of candidate directional signals, cell surface receptors, and signaling pathways, that may be involved in polarizing multipolar cells and stabilizing a pia-directed leading process for radial migration. Other signals are implicated in starting multipolar migration and triggering axon outgrowth. Here we review the molecules and mechanisms that regulate multipolar migration, and also discuss how multipolar migration affects the orderly arrangement of neurons in layers and columns in the developing neocortex. PMID:25452716

  12. Multipolar Coupling in Hybrid Metal–Dielectric Metasurfaces

    SciTech Connect

    Guo, Rui; Rusak, Evgenia; Staude, Isabelle; Dominguez, Jason; Decker, Manuel; Rockstuhl, Carsten; Brener, Igal; Neshev, Dragomir N.; Kivshar, Yuri S.

    2016-03-02

    In this paper, we study functional hybrid metasurfaces consisting of metal–dielectric nanoantennas that direct light from an incident plane wave or from localized light sources into a preferential direction. The directionality is obtained by carefully balancing the multipolar contributions to the scattering response from the constituents of the metasurface. The hybrid nanoantennas are composed of a plasmonic gold nanorod acting as a feed element and a silicon nanodisk acting as a director element. In order to experimentally realize this design, we have developed a two-step electron-beam lithography process in combination with a precision alignment step. Finally, the optical response of the fabricated sample is measured and reveals distinct signatures of coupling between the plasmonic and the dielectric nanoantenna elements that ultimately leads to unidirectional radiation of light.

  13. Multipolar blackbody radiation shifts for single-ion clocks

    NASA Astrophysics Data System (ADS)

    Arora, Bindiya; Nandy, D. K.; Sahoo, B. K.

    2012-01-01

    Appraising the projected 10-18 fractional uncertainty in the optical frequency standards using singly ionized ions, we estimate the blackbody radiation (BBR) shifts due to the magnetic dipole (M1) and electric quadrupole (E2) multipoles of the applied external electromagnetic field. Multipolar scalar polarizabilities are determined for the singly ionized calcium (Ca+) and strontium (Sr+) ions using the relativistic coupled-cluster method, though the theory can be exercised for any single-ion clocks. The expected energy shifts for the respective clock transitions are estimated to be 4.38(3)×10-4 Hz for Ca+ and 9.50(7)×10-5 Hz for Sr+. These shifts are large enough and may be a prerequisite for the frequency standards to achieve the foreseen 10-18 precision goal.

  14. Multipolar Coupling in Hybrid Metal–Dielectric Metasurfaces

    DOE PAGES

    Guo, Rui; Rusak, Evgenia; Staude, Isabelle; ...

    2016-03-02

    In this paper, we study functional hybrid metasurfaces consisting of metal–dielectric nanoantennas that direct light from an incident plane wave or from localized light sources into a preferential direction. The directionality is obtained by carefully balancing the multipolar contributions to the scattering response from the constituents of the metasurface. The hybrid nanoantennas are composed of a plasmonic gold nanorod acting as a feed element and a silicon nanodisk acting as a director element. In order to experimentally realize this design, we have developed a two-step electron-beam lithography process in combination with a precision alignment step. Finally, the optical response ofmore » the fabricated sample is measured and reveals distinct signatures of coupling between the plasmonic and the dielectric nanoantenna elements that ultimately leads to unidirectional radiation of light.« less

  15. Multipolar interference for non-reciprocal nonlinear generation

    NASA Astrophysics Data System (ADS)

    Poutrina, Ekaterina; Urbas, Augustine

    2016-04-01

    We show that nonlinear multipolar interference allows achieving not only unidirectional, but also non-reciprocal nonlinear generation from a nanoelement, with the direction of the produced light decoupled from the direction of at least one of the excitation beams. Alternatively, it may allow inhibiting the specified nonlinear response in a nanoelement or in its periodic arrangement by reversing the direction of one of the pumps. These general phenomena exploit the fact that, contrary to the linear response case, nonlinear magneto-electric interference stems from a combination of additive and multiplicative processes and includes an interference between various terms within the electric and magnetic partial waves themselves. We demonstrate the introduced concept numerically using an example of a plasmonic dimer geometry with realistic material parameters.

  16. Multipolar interference for non-reciprocal nonlinear generation

    PubMed Central

    Poutrina, Ekaterina; Urbas, Augustine

    2016-01-01

    We show that nonlinear multipolar interference allows achieving not only unidirectional, but also non-reciprocal nonlinear generation from a nanoelement, with the direction of the produced light decoupled from the direction of at least one of the excitation beams. Alternatively, it may allow inhibiting the specified nonlinear response in a nanoelement or in its periodic arrangement by reversing the direction of one of the pumps. These general phenomena exploit the fact that, contrary to the linear response case, nonlinear magneto-electric interference stems from a combination of additive and multiplicative processes and includes an interference between various terms within the electric and magnetic partial waves themselves. We demonstrate the introduced concept numerically using an example of a plasmonic dimer geometry with realistic material parameters. PMID:27126209

  17. Does Size Matter? The Multipolar International Landscape of Nanoscience

    PubMed Central

    Jensen, Pablo; Kreimer, Pablo

    2016-01-01

    How do different countries tackle nanoscience research? Are all countries similar except for a trivial size effect, as science is often assumed to be universal? Or does size dictate large differences, as large countries are able to develop activities in all directions of research, while small countries have to specialize in some specific niches? Alternatively, is size irrelevant, as all countries have followed different historical paths, leading to different patterns of specialisation? Here, we develop an original method that uses a bottom-up definition of scientific subfields to map the international structure of any scientific field. Our analysis shows that nanoscience research does not show a universal pattern of specialisation, homothetic of that of a single global leader (e.g., the United States). Instead, we find a multipolar world, with four main ways of doing nanosciences. PMID:27992439

  18. Nanoscale interference patterns of gap-mode multipolar plasmonic fields.

    PubMed

    Tanaka, Yoshito; Sanada, Akio; Sasaki, Keiji

    2012-01-01

    Arbitrary spatial distributions of the electric field of light are formed through the interference of individual wavenumber mode fields with appropriate amplitudes and phases, while the maximum wavenumber in the far field is limited by the wavelength of light. In contrast, localized surface plasmons (LSPs) possess the ability to confine photons strongly into nanometer-scale areas, exceeding the diffraction limit. In particular, gap-mode LSPs produce single-nanometer-sized, highly intense localized fields, known as hot spots. Here, we show the nanoscale spatial profiles of the LSP fields within hot spots, which exhibit complicated fine structures, rather than single peaks. The nanopatterns are created by constructive and destructive interferences of dipolar, quadrupolar, and higher-order multipolar plasmonic modes, which can be drastically altered by controlling parameters of the excitation optical system. The analysis in this study would be useful for proposing new concepts for manipulation and control of light-matter interactions in nanospaces.

  19. Does Size Matter? The Multipolar International Landscape of Nanoscience.

    PubMed

    Levin, Luciano; Jensen, Pablo; Kreimer, Pablo

    2016-01-01

    How do different countries tackle nanoscience research? Are all countries similar except for a trivial size effect, as science is often assumed to be universal? Or does size dictate large differences, as large countries are able to develop activities in all directions of research, while small countries have to specialize in some specific niches? Alternatively, is size irrelevant, as all countries have followed different historical paths, leading to different patterns of specialisation? Here, we develop an original method that uses a bottom-up definition of scientific subfields to map the international structure of any scientific field. Our analysis shows that nanoscience research does not show a universal pattern of specialisation, homothetic of that of a single global leader (e.g., the United States). Instead, we find a multipolar world, with four main ways of doing nanosciences.

  20. Induction synchrotron

    NASA Astrophysics Data System (ADS)

    Takayama, Ken; Kishiro, Junichi

    2000-08-01

    A novel proton synchrotron employing induction cells instead of radio frequency cavities is proposed. The major feature of the barrier bucket acceleration, where acceleration and longitudinal focusing are independently achieved is theoretically discussed with the help of multi-particle simulations. It is proved that barrier bucket acceleration allows ultimate use of longitudinal phase-space and is quite effective to substantially increase the beam intensity in synchrotrons. Engineering aspects of key devices to realize the novel synchrotron, a ferri/ferro-magnetic material loaded induction cell and a modulator being rapidly switched in synchronization with beam acceleration are described in detail. The idea is applied to an existing machine (the KEK 12 GeV-PS) and high-intensity proton rings such as JHF, ESS, and SNS and their predicted improvement in machine performance is given with numerical values for each case.

  1. Prdm8 regulates the morphological transition at multipolar phase during neocortical development.

    PubMed

    Inoue, Mayuko; Kuroda, Takao; Honda, Aya; Komabayashi-Suzuki, Mariko; Komai, Tae; Shinkai, Yoichi; Mizutani, Ken-ichi

    2014-01-01

    Here, we found that the PR domain protein Prdm8 serves as a key regulator of the length of the multipolar phase by controlling the timing of morphological transition. We used a mouse line with expression of Prdm8-mVenus reporter and found that Prdm8 is predominantly expressed in the middle and upper intermediate zone during both the late and terminal multipolar phases. Prdm8 expression was almost coincident with Unc5D expression, a marker for the late multipolar phase, although the expression of Unc5D was found to be gradually down-regulated to the point at which mVenus expression was gradually up-regulated. This expression pattern suggests the possible involvement of Prdm8 in the control of the late and terminal multipolar phases, which controls the timing for morphological transition. To test this hypothesis, we performed gain- and loss-of-function analysis of neocortical development by using in utero electroporation. We found that the knockdown of Prdm8 results in premature change from multipolar to bipolar morphology, whereas the overexpression of Prdm8 maintained the multipolar morphology. Additionally, the postnatal analysis showed that the Prdm8 knockdown stimulated the number of early born neurons, and differentiated neurons located more deeply in the neocortex, however, majority of those cells could not acquire molecular features consistent with laminar location. Furthermore, we found the candidate genes that were predominantly utilized in both the late and terminal multipolar phases, and these candidate genes included those encoding for guidance molecules. In addition, we also found that the expression level of these guidance molecules was inhibited by the introduction of the Prdm8 expression vector. These results indicate that the Prdm8-mediated regulation of morphological changes that normally occur during the late and terminal multipolar phases plays an important role in neocortical development.

  2. Multipolar migration: the third mode of radial neuronal migration in the developing cerebral cortex.

    PubMed

    Tabata, Hidenori; Nakajima, Kazunori

    2003-11-05

    Two distinct modes of radial neuronal migration, locomotion and somal translocation, have been reported in the developing cerebral cortex. Although these two modes of migration have been well documented, the cortical intermediate zone contains abundant multipolar cells, and they do not resemble the cells migrating by locomotion or somal translocation. Here, we report that these multipolar cells express neuronal markers and extend multiple thin processes in various directions independently of the radial glial fibers. Time-lapse analysis of living slices revealed that the multipolar cells do not have any fixed cell polarity, and that they very dynamically extend and retract multiple processes as their cell bodies slowly move. They do not usually move straight toward the pial surface during their radial migration, but instead frequently change migration direction and rate; sometimes they even remain in almost the same position, especially when they are in the subventricular zone. Occasionally, the multipolar cells jump tangentially during their radial migration. Because the migration modality of these cells clearly differs from locomotion or somal translocation, we refer to their novel type of migration as "multipolar migration." In view of the high proportion of cells exhibiting multipolar migration, this third mode of radial migration must be an important type of migration in the developing cortex.

  3. Multipolar correlations between reactants in crystalline and semiamorphous zeolites

    SciTech Connect

    Mandeville, J.B.; Golub, J.; Kozak, J.J.

    1988-03-24

    The authors study the role of multipolar correlations in influencing the efficiency of reaction between a fixed target molecule and a diffusing coreactant in zeolites that exhibit both crystalline and semiamorphous structures. They focus on zeolite A and construct a geometrical model whose framework structure and attendant channel patterns have the same topology as the 26-hedral cavities of type I of this aluminosilicate. They consider reaction partners interacting via (attractiverepulsive) ion-ion, angle-averaged ion-dipole, and angle-averaged dipole-dipole potentials V(r), and by coupling the theory of finite Markov processes with a lattice version of the Debye-Smoluchowski theory of encounter-controlled reactions, they quantify the differences in the diffusion-controlled rate constant k/sub D/ for reactions taking place in crystalline regions of finite extent (rafts) versus those occurring in crystalline regions surrounded by an amorphous aluminosilicate structure. Calculations based on the model introduced in this paper suggest that much of the marked cation-exchange activity and catalytic activity of fully crystalline zeolites is already captured by semiamorphous zeolites containing raft structures having the spatial extent of those found in recent experimental work by Thomas and Bursill

  4. Potential applications of multipolarization SAR for pine plantation biomass estimation

    NASA Technical Reports Server (NTRS)

    Wu, S. T.

    1985-01-01

    This study was conducted as a part of the research tasks under the Radar Land Cover Analysis Program. The Radar Land Cover Analysis objective is, through utilization of multisensor data, to gain a basic understanding of the measurements and data characteristics in the visible-IR-microwave regions of the electromagnetic spectrum associated with specific surface features and cover types. Since the results of analysis of data acquired by Shuttle Imaging Radar (SIR-A) and LANDSAT Thematic Mapper (TM) over the study area were reported (NSTL/ERL Report No. 228, December 1984), this study focused on the analysis and evaluation of the L-band multipolarization airborne SAR data acquired over a southeastern pine forest scene. The data acquisition mission was flown on September 8 and 9, 1983. The HH, HV polarizations and the VV, VH polarizations were used on the first and the second day, respectively. Due to instrumentation difficulties, the digital recorder recorded only the second day's data. Because of this, only the VV and VH polarization data were used in this analysis. However, the HH and HV polarization images were available for visual comparison. It appears that SAR digital numbers correlate with the index of green biomass.

  5. Configuration analysis and optimization on multipolar Galatea trap

    NASA Astrophysics Data System (ADS)

    Tong, W. M.; Tao, B. Q.; Jin, X. J.; Li, Z. W.

    2016-10-01

    Multipolar Galatea magnetic trap simulation model was established with the finite element simulation software COMSOL Multiphysics. Analyses about the magnetic section configuration show that better magnetic configuration should make more plasma stay in the weak magnetic field rather than the annular magnetic shell field. Then an optimization model was established with axial electromagnetic force, weak magnetic field area and average magnetic mirror ratio as the optimization goals and with the currents of myxines as design variables. Select appropriate weight coefficients and get optimization results by applying genetic algorithm. Results show that the superiority of the target value of typical application parameters, including the average magnetic mirror can reduce more than 5%, the weak magnetic field area can increase at least 65%, at the same time, axial electromagnetic force acting on the outer myxines can be reduced to less than 50 N. Finally, the results were proved by COMSOL Multiphysics and the results proved the optimized magnetic trap configuration with more plasma in the weak magnetic field can reduce the plasma diffusion velocity and is more conducive for the constraint of plasma.

  6. Configuration analysis and optimization on multipolar Galatea trap

    SciTech Connect

    Tong, W. M. Tao, B. Q.; Jin, X. J.; Li, Z. W.

    2016-10-15

    Multipolar Galatea magnetic trap simulation model was established with the finite element simulation software COMSOL Multiphysics. Analyses about the magnetic section configuration show that better magnetic configuration should make more plasma stay in the weak magnetic field rather than the annular magnetic shell field. Then an optimization model was established with axial electromagnetic force, weak magnetic field area and average magnetic mirror ratio as the optimization goals and with the currents of myxines as design variables. Select appropriate weight coefficients and get optimization results by applying genetic algorithm. Results show that the superiority of the target value of typical application parameters, including the average magnetic mirror can reduce more than 5%, the weak magnetic field area can increase at least 65%, at the same time, axial electromagnetic force acting on the outer myxines can be reduced to less than 50 N. Finally, the results were proved by COMSOL Multiphysics and the results proved the optimized magnetic trap configuration with more plasma in the weak magnetic field can reduce the plasma diffusion velocity and is more conducive for the constraint of plasma.

  7. A multipolar approach to the interatomic covalent interaction energy.

    PubMed

    Francisco, Evelio; Menéndez Crespo, Daniel; Costales, Aurora; Martín Pendás, Ángel

    2017-04-30

    Interatomic exchange-correlation energies correspond to the covalent energetic contributions to an interatomic interaction in real space theories of the chemical bond, but their widespread use is severely limited due to their computationally intensive character. In the same way as the multipolar (mp) expansion is customary used in biomolecular modeling to approximate the classical Coulomb interaction between two charge densities ρA(r) and ρB(r), we examine in this work the mp approach to approximate the interatomic exchange-correlation (xc) energies of the Interacting Quantum Atoms method. We show that the full xc mp series is quickly divergent for directly bonded atoms (1-2 pairs) albeit it works reasonably well most times for 1- n (n > 2) interactions. As with conventional perturbation theory, we show numerically that the xc series is asymptotically convergent and that, a truncated xc mp approximation retaining terms up to l1+l2=2 usually gives relatively accurate results, sometimes even for directly bonded atoms. Our findings are supported by extensive numerical analyses on a variety of systems that range from several standard hydrogen bonded dimers to typically covalent or aromatic molecules. The exact algebraic relationship between the monopole-monopole xc mp term and the inter-atomic bond order, as measured by the delocalization index of the quantum theory of atoms in molecules, is also established. © 2017 Wiley Periodicals, Inc.

  8. Ordering in linear multipolar colloids driven by an external field.

    PubMed

    Alarcón-Waess, O

    2006-08-14

    An approach to describe a linear multipolar colloid driven by an external field is developed by considering a colloid which in absence of the field is low structured and its coupling potential is axially symmetric. The equilibrium correlation of one component of the orientation tensor, self and collective, is computed up to linear order in density, which can be measured in an appropriate light scattering experiment. The self-correlation is written in terms of the second and fourth order parameters. All the equilibrium quantities are computed up to two-body level. This is done by assuming that the two-body equilibrium density function is given by the Boltzmann distribution, whereas the one-body density function is computed as solution of the equilibrium N-body Smoluchowski equation in the absence of hydrodynamic interactions. These observables, self and collective, as well as the second and fourth order parameters are able to describe when the colloid would evolve to an orientationally ordered phase. Explicit results for the dipole and quadrupole moments are reported. These results predict a different alignment with the external field for each moment. A relationship is provided between second and fourth order parameters, predicting the critical value of the external field in which the colloid goes into an axially symmetric phase.

  9. Relationships between multipolarized radar backscatter and slash pine stand parameters

    NASA Technical Reports Server (NTRS)

    Hussin, Yousif Ali; Hoffer, Roger M.

    1989-01-01

    Multipolarized L-band (24.5 cm) aircraft radar data was obtained for a primarily forested area in northern Florida. Based on the results of previous studies by Hoffer and Hussin (1989), a swath of medium incidence angle (35-25 deg) data was defined. Three groups of slash pine stands were located in the data: 4- to 17-year-old plantations, 18- to 48-year-old plantations, and 16- to 53-year-old natural stands. Stand data obtained from the forest-products companies operating in the area include age, tree height, diameter-at-breast height, basal area, volume (cords/acre), and density (trees/acre). Each of these stand parameters were compared to each of the four polarizations (HH, VV, VH, and HV) of the radar data for each group of stands. Statistically significant relationships were found between the radar backscatter and the forest stand parameters only for the 4- to 17-year-old slash pine plantation stands. In general, the cross-polarized radar backscatter was more highly correlated with the various stand parameters than the like-polarized backscatter, and the VV-polarized data were more highly correlated than the HH-polarized data.

  10. A simple and practical control of the authenticity of organic sugarcane samples based on the use of machine-learning algorithms and trace elements determination by inductively coupled plasma mass spectrometry.

    PubMed

    Barbosa, Rommel M; Batista, Bruno L; Barião, Camila V; Varrique, Renan M; Coelho, Vinicius A; Campiglia, Andres D; Barbosa, Fernando

    2015-10-01

    A practical and easy control of the authenticity of organic sugarcane samples based on the use of machine-learning algorithms and trace elements determination by inductively coupled plasma mass spectrometry is proposed. Reference ranges for 32 chemical elements in 22 samples of sugarcane (13 organic and 9 non organic) were established and then two algorithms, Naive Bayes (NB) and Random Forest (RF), were evaluated to classify the samples. Accurate results (>90%) were obtained when using all variables (i.e., 32 elements). However, accuracy was improved (95.4% for NB) when only eight minerals (Rb, U, Al, Sr, Dy, Nb, Ta, Mo), chosen by a feature selection algorithm, were employed. Thus, the use of a fingerprint based on trace element levels associated with classification machine learning algorithms may be used as a simple alternative for authenticity evaluation of organic sugarcane samples.

  11. Multi-Polarization Reconfigurable Antenna for Wireless Biomedical System.

    PubMed

    Wong, Hang; Lin, Wei; Huitema, Laure; Arnaud, Eric

    2017-06-01

    This paper presents a multi-polarization reconfigurable antenna with four dipole radiators for biomedical applications in body-centric wireless communication system (BWCS). The proposed multi-dipole antenna with switchable 0°, +45°, 90° and -45° linear polarizations is able to overcome the polarization mismatching and multi-path distortion in complex wireless channels as in BWCS. To realize this reconfigurable feature for the first time among all the reported antenna designs, we assembled four dipoles together with 45° rotated sequential arrangements. These dipoles are excited by the same feeding source provided by a ground tapered Balun. A metallic reflector is placed below the dipoles to generate a broadside radiation. By introducing eight PIN diodes as RF switches between the excitation source and the four dipoles, we can control a specific dipole to operate. As the results, 0°, +45°, 90° and -45° linear polarizations can be switched correspondingly to different operating dipoles. Experimental results agree with the simulation and show that the proposed antenna well works in all polarization modes with desirable electrical characteristics. The antenna has a wide impedance bandwidth of 34% from 2.2 to 3.1 GHz (for the reflection coefficient ≤ -10 dB) and exhibits a stable cardioid-shaped radiation pattern across the operating bandwidth with a peak gain of 5.2 dBi. To validate the effectiveness of the multi-dipole antenna for biomedical applications, we also designed a meandered PIFA as the implantable antenna. Finally, the communication link measurement shows that our proposed antenna is able to minimize the polarization mismatching and maintains the optimal communication link thanks to its polarization reconfigurability.

  12. Electrophysiological channel interactions using focused multipolar stimulation for cochlear implants

    NASA Astrophysics Data System (ADS)

    George, Shefin S.; Shivdasani, Mohit N.; Wise, Andrew K.; Shepherd, Robert K.; Fallon, James B.

    2015-12-01

    Objective. Speech intelligibility with existing multichannel cochlear implants (CIs) is thought to be limited by poor spatial selectivity and interactions between CI channels caused by overlapping activation with monopolar (MP) stimulation. Our previous studies have shown that focused multipolar (FMP) and tripolar (TP) stimulation produce more restricted neural activation in the inferior colliculus (IC), compared to MP stimulation. Approach. This study explored interactions in the IC produced by simultaneous stimulation of two CI channels. We recorded multi-unit neural activity in the IC of anaesthetized cats with normal and severely degenerated spiral ganglion neuron populations in response to FMP, TP and MP stimulation from a 14 channel CI. Stimuli were applied to a ‘fixed’ CI channel, chosen toward the middle of the cochlear electrode array, and the effects of simultaneously stimulating a more apical ‘test’ CI channel were measured as a function of spatial separation between the two stimulation channels and stimulus level of the fixed channel. Channel interactions were quantified by changes in neural responses and IC threshold (i.e., threshold shift) elicited by simultaneous stimulation of two CI channels, compared to stimulation of the test channel alone. Main results. Channel interactions were significantly lower for FMP and TP than for MP stimulation (p < 0.001), whereas no significant difference was observed between FMP and TP stimulation. With MP stimulation, threshold shifts increased with decreased inter-electrode spacing and increased stimulus levels of the fixed channel. For FMP and TP stimulation, channel interactions were found to be similar for different inter-electrode spacing and stimulus levels of the fixed channel. Significance. The present study demonstrates how the degree of channel interactions in a CI can be controlled using stimulation configurations such as FMP and TP; such knowledge is essential in enhancing CI function in complex

  13. Potential application of multipolarization SAR for pine-plantation biomass estimation

    NASA Technical Reports Server (NTRS)

    Wu, Shih-Tseng

    1987-01-01

    This paper presents the technique and the potential utility of multipolarization Synthetic Aperture Radar (SAR) data for pine-plantation biomass estimation. Three channels of SAR data, one from the Shuttle Imaging Radar SIR-A and the other two from the aircraft SAR, were acquired over the Baldwin County, Alabama, study area. The SIR-A data were acquired with HH polarization and the aircraft SAR data with VV and VH polarizations. Linear regression techniques are used to estimate the pine-plantation biomass, tree height, and age using 21 test plots. The results indicate that the multipolarization data are highly related to the plantation biomass. The results suggest a potential application of multipolarization SAR for pine-plantation biomass estimation.

  14. Planar multipolar cells in the cochlear nucleus project to medial olivocochlear neurons in mouse.

    PubMed

    Darrow, Keith N; Benson, Thane E; Brown, M Christian

    2012-05-01

    Medial olivocochlear (MOC) neurons originate in the superior olivary complex and project to the cochlea, where they act to reduce the effects of noise masking and protect the cochlea from damage. MOC neurons respond to sound via a reflex pathway; however, in this pathway the cochlear nucleus cell type that provides input to MOC neurons is not known. We investigated whether multipolar cells of the ventral cochlear nucleus have projections to MOC neurons by labeling them with injections into the dorsal cochlear nucleus. The projections of one type of labeled multipolar cell, planar neurons, were traced into the ventral nucleus of the trapezoid body, where they were observed terminating on MOC neurons (labeled in some cases by a second cochlear injection of FluoroGold). These terminations formed what appear to be excitatory synapses, i.e., containing small, round vesicles and prominent postsynaptic densities. These data suggest that cochlear nucleus planar multipolar neurons drive the MOC neuron's response to sound.

  15. Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos.

    PubMed

    Vitale, Ilio; Senovilla, Laura; Jemaà, Mohamed; Michaud, Mickaël; Galluzzi, Lorenzo; Kepp, Oliver; Nanty, Lisa; Criollo, Alfredo; Rello-Varona, Santiago; Manic, Gwenola; Métivier, Didier; Vivet, Sonia; Tajeddine, Nicolas; Joza, Nicholas; Valent, Alexander; Castedo, Maria; Kroemer, Guido

    2010-04-07

    Tetraploidy can constitute a metastable intermediate between normal diploidy and oncogenic aneuploidy. Here, we show that the absence of p53 is not only permissive for the survival but also for multipolar asymmetric divisions of tetraploid cells, which lead to the generation of aneuploid cells with a near-to-diploid chromosome content. Multipolar mitoses (which reduce the tetraploid genome to a sub-tetraploid state) are more frequent when p53 is downregulated and the product of the Mos oncogene is upregulated. Mos inhibits the coalescence of supernumerary centrosomes that allow for normal bipolar mitoses of tetraploid cells. In the absence of p53, Mos knockdown prevents multipolar mitoses and exerts genome-stabilizing effects. These results elucidate the mechanisms through which asymmetric cell division drives chromosomal instability in tetraploid cells.

  16. Multipolar mitosis of tetraploid cells: inhibition by p53 and dependency on Mos

    PubMed Central

    Vitale, Ilio; Senovilla, Laura; Jemaà, Mohamed; Michaud, Mickaël; Galluzzi, Lorenzo; Kepp, Oliver; Nanty, Lisa; Criollo, Alfredo; Rello-Varona, Santiago; Manic, Gwenola; Métivier, Didier; Vivet, Sonia; Tajeddine, Nicolas; Joza, Nicholas; Valent, Alexander; Castedo, Maria; Kroemer, Guido

    2010-01-01

    Tetraploidy can constitute a metastable intermediate between normal diploidy and oncogenic aneuploidy. Here, we show that the absence of p53 is not only permissive for the survival but also for multipolar asymmetric divisions of tetraploid cells, which lead to the generation of aneuploid cells with a near-to-diploid chromosome content. Multipolar mitoses (which reduce the tetraploid genome to a sub-tetraploid state) are more frequent when p53 is downregulated and the product of the Mos oncogene is upregulated. Mos inhibits the coalescence of supernumerary centrosomes that allow for normal bipolar mitoses of tetraploid cells. In the absence of p53, Mos knockdown prevents multipolar mitoses and exerts genome-stabilizing effects. These results elucidate the mechanisms through which asymmetric cell division drives chromosomal instability in tetraploid cells. PMID:20186124

  17. Numerical simulation of multipolar configuration and prepulse technique to obtain spatially reverse recruitment order.

    PubMed

    Dali, Melissa; Rossel, Olivier; Guiraud, David

    2016-08-01

    In the context of functional electrical stimulation of peripheral nerves, the control of a specific motor or sensory functions may need selective stimulation to target the desired effect without others. In implanted stimulation, spatial selectivity is obtained using multipolar CUFF electrodes with specific spread of the current over each contact. Furthermore, electrical stimulation recruits large fibers before small ones, whereas the targeted function could be elicited by a specific fiber type i.e. fiber diameter. In our work, numerical simulations were used to investigate the combination of multipolar configuration and prepulses, in order to obtain spatially reverse recruitment order. Multipolar stimulation provides efficient spatial selectivity, whereas sub-threshold prepulses were used to reverse recruitment order with a reasonable increase of the injected charges. We compared several selective configurations combined with prepulses to show that some are able to guarantee both the spatial selectivity while one fiber's diameter can be preferentially activated.

  18. Potential application of multipolarization SAR for pine-plantation biomass estimation

    SciTech Connect

    Wu, S.T.

    1987-05-01

    This paper presents the techniques and the potential utility of multipolarization Synthetic Aperture Radar (SAR) data for pine-plantation biomass estimation. Three channels of SAR data, one from the Shuttle Imaging Radar SIR-A and the other two from the aircraft SAR, were acquired over the Baldwin County, Alabama, study area. The SIR-A data were acquired with HH polarization and the aircraft SAR data with VV and VH polarizations. Linear regression techniques are used to estimate the pine-plantation biomass, tree height, and age using 21 test plots. The results indicate that the multipolarization data are highly related to the plantation biomass. The results suggest a potential application of multipolarization SAR for pine-plantation biomass estimation.

  19. Short-Term Results of Laparoscopic Radiofrequency Ablation Using a Multipolar System for Localized Hepatocellular Carcinoma

    PubMed Central

    Morimoto, Naoki; Isoda, Norio; Takaoka, Yoshinari; Hirosawa, Takuya; Watanabe, Shunji; Otake, Toshiya; Murayama, Kozue; Fujieda, Takeshi; Tsukui, Mamiko; Miyata, Natsumi; Ono, Kohei; Yamaguchi, Shota; Yamamoto, Hironori

    2017-01-01

    Background and Aim Multipolar radiofrequency ablation (RFA) is feasible for the treatment of hepatocellular carcinoma (HCC) for which a large ablative area is planned, and it imposes a light physical burden on patients. Multipolar RFA via the percutaneous approach is performed in the majority of cases, but the efficacy of multipolar RFA with a laparoscopic approach has rarely been studied. This study aimed to evaluate the efficacy and safety of multipolar laparoscopic RFA (LRA) for localized HCC over the short term. Methods From January 2014 to January 2016, 77 consecutive patients with 130 HCCs treated by multipolar LRA were assessed. One to three bipolar needle applicators were inserted under laparoscopic ultrasonography guidance, regardless of tumor location. We intended to achieve parallel insertions and no-touch ablation as much as possible. Results The median size of the main tumor was 22 mm (range, 10-42 mm). The median follow-up time was 13.6 months (range, 3.1-24.8 months). In all cases, a sufficient ablative area was obtained as planned, without thermal injury of adjacent organs. During the follow-up period, all patients were alive with no local tumor progression, while intrahepatic recurrence distant from the primary site occurred in 7 patients. The 2-year local tumor progression-free survival rate and overall cancer-free survival rate were 100 and 81.6%, respectively. There were no procedural major complications caused prolonging the hospitalization, and all patients were discharged without subjective symptoms 4-7 days after LRA. Conclusions Multipolar LRA was efficacious in the treatment of localized HCCs by safely achieving a good ablative area. PMID:28275580

  20. Machine Learning

    NASA Astrophysics Data System (ADS)

    Hoffmann, Achim; Mahidadia, Ashesh

    The purpose of this chapter is to present fundamental ideas and techniques of machine learning suitable for the field of this book, i.e., for automated scientific discovery. The chapter focuses on those symbolic machine learning methods, which produce results that are suitable to be interpreted and understood by humans. This is particularly important in the context of automated scientific discovery as the scientific theories to be produced by machines are usually meant to be interpreted by humans. This chapter contains some of the most influential ideas and concepts in machine learning research to give the reader a basic insight into the field. After the introduction in Sect. 1, general ideas of how learning problems can be framed are given in Sect. 2. The section provides useful perspectives to better understand what learning algorithms actually do. Section 3 presents the Version space model which is an early learning algorithm as well as a conceptual framework, that provides important insight into the general mechanisms behind most learning algorithms. In section 4, a family of learning algorithms, the AQ family for learning classification rules is presented. The AQ family belongs to the early approaches in machine learning. The next, Sect. 5 presents the basic principles of decision tree learners. Decision tree learners belong to the most influential class of inductive learning algorithms today. Finally, a more recent group of learning systems are presented in Sect. 6, which learn relational concepts within the framework of logic programming. This is a particularly interesting group of learning systems since the framework allows also to incorporate background knowledge which may assist in generalisation. Section 7 discusses Association Rules - a technique that comes from the related field of Data mining. Section 8 presents the basic idea of the Naive Bayesian Classifier. While this is a very popular learning technique, the learning result is not well suited for

  1. Accuracy and tractability of a kriging model of intramolecular polarizable multipolar electrostatics and its application to histidine.

    PubMed

    Kandathil, Shaun M; Fletcher, Timothy L; Yuan, Yongna; Knowles, Joshua; Popelier, Paul L A

    2013-08-05

    We propose a generic method to model polarization in the context of high-rank multipolar electrostatics. This method involves the machine learning technique kriging, here used to capture the response of an atomic multipole moment of a given atom to a change in the positions of the atoms surrounding this atom. The atoms are malleable boxes with sharp boundaries, they do not overlap and exhaust space. The method is applied to histidine where it is able to predict atomic multipole moments (up to hexadecapole) for unseen configurations, after training on 600 geometries distorted using normal modes of each of its 24 local energy minima at B3LYP/apc-1 level. The quality of the predictions is assessed by calculating the Coulomb energy between an atom for which the moments have been predicted and the surrounding atoms (having exact moments). Only interactions between atoms separated by three or more bonds ("1, 4 and higher" interactions) are included in this energy error. This energy is compared with that of a central atom with exact multipole moments interacting with the same environment. The resulting energy discrepancies are summed for 328 atom-atom interactions, for each of the 29 atoms of histidine being a central atom in turn. For 80% of the 539 test configurations (outside the training set), this summed energy deviates by less than 1 kcal mol(-1). Copyright © 2013 Wiley Periodicals, Inc.

  2. p53 Dependent Centrosome Clustering Prevents Multipolar Mitosis in Tetraploid Cells

    PubMed Central

    Yi, Qiyi; Zhao, Xiaoyu; Huang, Yun; Ma, Tieliang; Zhang, Yingyin; Hou, Heli; Cooke, Howard J.; Yang, Da-Qing; Wu, Mian; Shi, Qinghua

    2011-01-01

    Background p53 abnormality and aneuploidy often coexist in human tumors, and tetraploidy is considered as an intermediate between normal diploidy and aneuploidy. The purpose of this study was to investigate whether and how p53 influences the transformation from tetraploidy to aneuploidy. Principal Findings Live cell imaging was performed to determine the fates and mitotic behaviors of several human and mouse tetraploid cells with different p53 status, and centrosome and spindle immunostaining was used to investigate centrosome behaviors. We found that p53 dominant-negative mutation, point mutation, or knockout led to a 2∼ 33-fold increase of multipolar mitosis in N/TERT1, 3T3 and mouse embryonic fibroblasts (MEFs), while mitotic entry and cell death were not significantly affected. In p53-/- tetraploid MEFs, the ability of centrosome clustering was compromised, while centrosome inactivation was not affected. Suppression of RhoA/ROCK activity by specific inhibitors in p53-/- tetraploid MEFs enhanced centrosome clustering, decreased multipolar mitosis from 38% to 20% and 16% for RhoA and ROCK, respectively, while expression of constitutively active RhoA in p53+/+ tetraploid 3T3 cells increased the frequency of multipolar mitosis from 15% to 35%. Conclusions p53 could not prevent tetraploid cells entering mitosis or induce tetraploid cell death. However, p53 abnormality impaired centrosome clustering and lead to multipolar mitosis in tetraploid cells by modulating the RhoA/ROCK signaling pathway. PMID:22076149

  3. Evidence of multipolar response of Bacteriorhodopsin by noncollinear second harmonic generation.

    PubMed

    Bovino, F A; Larciprete, M C; Sibilia, C; Váró, G; Gergely, C

    2012-06-18

    Noncollinear second harmonic generation from a Bacteriorhodopsin (BR) oriented multilayer film was systematically investigated by varying the polarization state of both fundamental beams. Both experimental results and theoretical simulations, show that the resulting polarization mapping is an useful tool to put in evidence the optical chirality of the investigated film as well as the corresponding multipolar contributions to the nonlinear.

  4. Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex.

    PubMed

    Liu, Xiuxin; Sun, Lin; Torii, Masaaki; Rakic, Pasko

    2012-05-22

    The prospective pyramidal neurons, migrating from the proliferative ventricular zone to the overlaying cortical plate, assume multipolar morphology while passing through the transient subventricular zone. Here, we show that this morphogenetic transformation, from the bipolar to the mutipolar and then back to bipolar again, is associated with expression of connexin 43 (Cx43) and, that knockdown of Cx43 retards, whereas its overexpression enhances, this morphogenetic process. In addition, we have observed that knockdown of Cx43 reduces expression of p27, whereas overexpression of p27 rescues the effect of Cx43 knockdown in the multipolar neurons. Furthermore, functional gap junction/hemichannel domain, and the C-terminal domain of Cx43, independently enhance the expression of p27 and promote the morphological transformation and migration of the multipolar neurons in the SVZ/IZ. Collectively, these results indicate that Cx43 regulates the passage of migrating neurons through their multipolar stage via p27 signaling and that interference with this process, by either genetic and/or environmental factors, may cause cortical malformations.

  5. Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex

    PubMed Central

    Liu, Xiuxin; Sun, Lin; Torii, Masaaki; Rakic, Pasko

    2012-01-01

    The prospective pyramidal neurons, migrating from the proliferative ventricular zone to the overlaying cortical plate, assume multipolar morphology while passing through the transient subventricular zone. Here, we show that this morphogenetic transformation, from the bipolar to the mutipolar and then back to bipolar again, is associated with expression of connexin 43 (Cx43) and, that knockdown of Cx43 retards, whereas its overexpression enhances, this morphogenetic process. In addition, we have observed that knockdown of Cx43 reduces expression of p27, whereas overexpression of p27 rescues the effect of Cx43 knockdown in the multipolar neurons. Furthermore, functional gap junction/hemichannel domain, and the C-terminal domain of Cx43, independently enhance the expression of p27 and promote the morphological transformation and migration of the multipolar neurons in the SVZ/IZ. Collectively, these results indicate that Cx43 regulates the passage of migrating neurons through their multipolar stage via p27 signaling and that interference with this process, by either genetic and/or environmental factors, may cause cortical malformations. PMID:22566616

  6. Corneal endothelial cells possess an elaborate multipolar shape to maximize the basolateral to apical membrane area

    PubMed Central

    Harrison, Theresa A.; He, Zhiguo; Boggs, Kristin; Thuret, Gilles; Liu, Hong-Xiang

    2016-01-01

    Purpose The corneal endothelium is widely believed to consist of geometrically regular cells interconnected by junctional complexes. However, while en face visualization of the endothelial apical surface reveals characteristic polygonal borders, the overall form of the component cells has rarely been observed. Methods To visualize the shape of individual endothelial cells within the native monolayer, two independent Cre/LoxP-based cell labeling approaches were used. In the first, a P0-Cre mouse driver strain was bred to an R26-tdTomato reporter line to map neural crest–derived endothelial cells with cytosolic red fluorescent protein. In the second, HPRT-Cre induction of small numbers of green and red fluorescent protein–filled cells within a background of unlabeled cells was achieved using a dual-color reporter system, mosaic analysis with double markers (MADM). Selective imaging of the endothelial lateral membranes at different apicobasal levels was accomplished after staining with antibodies to ZO-1 and the neural cell adhesion molecule (NCAM). Results When viewed in their entirety in whole-mount preparations, fluorescent protein–filled cells appear star-shaped, extending multiple dendritic processes that radiate outward in the plane of the monolayer. Examination of rare cases where cells expressing different fluorescent proteins lie directly adjacent to one another reveals that these long processes undergo extensive interdigitation. The resulting overlap allows individual cells to extend over a greater area than if the cell boundaries were mutually exclusive. Anti-NCAM staining of these interlocking peripheral cell extensions reveals an elaborate system of lateral membrane folds that, when viewed in optical sections, increase in complexity from the apical to the basal pole. This not only produces a substantial increase in the basolateral, relative to the apical, membrane but also greatly extends the paracellular pathway as a highly convoluted space

  7. Corneal endothelial cells possess an elaborate multipolar shape to maximize the basolateral to apical membrane area.

    PubMed

    Harrison, Theresa A; He, Zhiguo; Boggs, Kristin; Thuret, Gilles; Liu, Hong-Xiang; Defoe, Dennis M

    2016-01-01

    The corneal endothelium is widely believed to consist of geometrically regular cells interconnected by junctional complexes. However, while en face visualization of the endothelial apical surface reveals characteristic polygonal borders, the overall form of the component cells has rarely been observed. To visualize the shape of individual endothelial cells within the native monolayer, two independent Cre/LoxP-based cell labeling approaches were used. In the first, a P0-Cre mouse driver strain was bred to an R26-tdTomato reporter line to map neural crest-derived endothelial cells with cytosolic red fluorescent protein. In the second, HPRT-Cre induction of small numbers of green and red fluorescent protein-filled cells within a background of unlabeled cells was achieved using a dual-color reporter system, mosaic analysis with double markers (MADM). Selective imaging of the endothelial lateral membranes at different apicobasal levels was accomplished after staining with antibodies to ZO-1 and the neural cell adhesion molecule (NCAM). When viewed in their entirety in whole-mount preparations, fluorescent protein-filled cells appear star-shaped, extending multiple dendritic processes that radiate outward in the plane of the monolayer. Examination of rare cases where cells expressing different fluorescent proteins lie directly adjacent to one another reveals that these long processes undergo extensive interdigitation. The resulting overlap allows individual cells to extend over a greater area than if the cell boundaries were mutually exclusive. Anti-NCAM staining of these interlocking peripheral cell extensions reveals an elaborate system of lateral membrane folds that, when viewed in optical sections, increase in complexity from the apical to the basal pole. This not only produces a substantial increase in the basolateral, relative to the apical, membrane but also greatly extends the paracellular pathway as a highly convoluted space. Our analysis indicates that, far

  8. HIGH GRADIENT INDUCTION ACCELERATOR

    SciTech Connect

    Caporaso, G J; Sampayan, S; Chen, Y; Blackfield, D; Harris, J; Hawkins, S; Holmes, C; Krogh, M; Nelson, S; Nunnally, W; Paul, A; Poole, B; Rhodes, M; Sanders, D; Selenes, K; Sullivan, J; Wang, L; Watson, J

    2007-06-21

    A new type of compact induction accelerator is under development at the Lawrence Livermore National Laboratory that promises to increase the average accelerating gradient by at least an order of magnitude over that of existing induction machines. The machine is based on the use of high gradient vacuum insulators, advanced dielectric materials and switches and is stimulated by the desire for compact flash x-ray radiography sources. Research describing an extreme variant of this technology aimed at proton therapy for cancer will be described. Progress in applying this technology to several applications will be reviewed.

  9. Business Machines

    ERIC Educational Resources Information Center

    Pactor, Paul

    1970-01-01

    The U.S. Department of Labor has projected a 106 percent increase in the demand for office machine operators over the next 10 years. Machines with a high frequency of use include printing calculators, 10-key adding machines, and key punch machines. The 12th grade is the logical time for teaching business machines. (CH)

  10. Wnt signaling regulates multipolar-to-bipolar transition of migrating neurons in the cerebral cortex.

    PubMed

    Boitard, Michael; Bocchi, Riccardo; Egervari, Kristof; Petrenko, Volodymyr; Viale, Beatrice; Gremaud, Stéphane; Zgraggen, Eloisa; Salmon, Patrick; Kiss, Jozsef Z

    2015-03-03

    The precise timing of pyramidal cell migration from the ventricular germinal zone to the cortical plate is essential for establishing cortical layers, and migration errors can lead to neurodevelopmental disorders underlying psychiatric and neurological diseases. Here, we report that Wnt canonical as well as non-canonical signaling is active in pyramidal precursors during radial migration. We demonstrate using constitutive and conditional genetic strategies that transient downregulation of canonical Wnt/β-catenin signaling during the multipolar stage plays a critical role in polarizing and orienting cells for radial migration. In addition, we show that reduced canonical Wnt signaling is triggered cell autonomously by time-dependent expression of Wnt5A and activation of non-canonical signaling. We identify ephrin-B1 as a canonical Wnt-signaling-regulated target in control of the multipolar-to-bipolar switch. These findings highlight the critical role of Wnt signaling activity in neuronal positioning during cortical development.

  11. A novel network of multipolar bursting interneurons generates theta frequency oscillations in neocortex.

    PubMed

    Blatow, Maria; Rozov, Andrei; Katona, Istvan; Hormuzdi, Sheriar G; Meyer, Axel H; Whittington, Miles A; Caputi, Antonio; Monyer, Hannah

    2003-06-05

    GABAergic interneurons can phase the output of principal cells, giving rise to oscillatory activity in different frequency bands. Here we describe a new subtype of GABAergic interneuron, the multipolar bursting (MB) cell in the mouse neocortex. MB cells are parvalbumin positive but differ from fast-spiking multipolar (FS) cells in their morphological, neurochemical, and physiological properties. MB cells are reciprocally connected with layer 2/3 pyramidal cells and are coupled with each other by chemical and electrical synapses. MB cells innervate FS cells but not vice versa. MB to MB cell as well as MB to pyramidal cell synapses exhibit paired-pulse facilitation. Carbachol selectively induced synchronized theta frequency oscillations in MB cells. Synchrony required both gap junction coupling and GABAergic chemical transmission, but not excitatory glutamatergic input. Hence, MB cells form a distinct inhibitory network, which upon cholinergic drive can generate rhythmic and synchronous theta frequency activity, providing temporal coordination of pyramidal cell output.

  12. Hubble space telescope observations and geometric models of compact multipolar planetary nebulae

    SciTech Connect

    Hsia, Chih-Hao; Chau, Wayne; Zhang, Yong; Kwok, Sun E-mail: wwlljj1314@gmail.com E-mail: sunkwok@hku.hk

    2014-05-20

    We report high angular resolution Hubble Space Telescope observations of 10 compact planetary nebulae (PNs). Many interesting internal structures, including multipolar lobes, arcs, two-dimensional rings, tori, and halos, are revealed for the first time. These results suggest that multipolar structures are common among PNs, and these structures develop early in their evolution. From three-dimensional geometric models, we have determined the intrinsic dimensions of the lobes. Assuming the lobes are the result of interactions between later-developed fast winds and previously ejected asymptotic giant branch winds, the geometric structures of these PNs suggest that there are multiple phases of fast winds separated by temporal variations and/or directional changes. A scenario of evolution from lobe-dominated to cavity-dominated stages is presented. The results reported here will provide serious constraints on any dynamical models of PNs.

  13. Magnetar giant flares in multipolar magnetic fields. I. Fully and partially open eruptions of flux ropes

    SciTech Connect

    Huang, Lei; Yu, Cong E-mail: cyu@ynao.ac.cn

    2014-04-01

    We propose a catastrophic eruption model for the enormous energy release of magnetars during giant flares, in which a toroidal and helically twisted flux rope is embedded within a force-free magnetosphere. The flux rope stays in stable equilibrium states initially and evolves quasi-statically. Upon the loss of equilibrium, the flux rope cannot sustain the stable equilibrium states and erupts catastrophically. During the process, the magnetic energy stored in the magnetosphere is rapidly released as the result of destabilization of global magnetic topology. The magnetospheric energy that could be accumulated is of vital importance for the outbursts of magnetars. We carefully establish the fully open fields and partially open fields for various boundary conditions at the magnetar surface and study the relevant energy thresholds. By investigating the magnetic energy accumulated at the critical catastrophic point, we find that it is possible to drive fully open eruptions for dipole-dominated background fields. Nevertheless, it is hard to generate fully open magnetic eruptions for multipolar background fields. Given the observational importance of the multipolar magnetic fields in the vicinity of the magnetar surface, it would be worthwhile to explore the possibility of the alternative eruption approach in multipolar background fields. Fortunately, we find that flux ropes may give rise to partially open eruptions in the multipolar fields, which involve only partial opening of background fields. The energy release fractions are greater for cases with central-arcaded multipoles than those with central-caved multipoles that emerged in background fields. Eruptions would fail only when the centrally caved multipoles become extremely strong.

  14. Multipolar polarizabilities and two-body dispersion coefficients for Na by a variationally stable procedure

    NASA Astrophysics Data System (ADS)

    Sun, Qiu-Feng; Huang, Shi-Zhong

    2011-11-01

    Based on the weakest bound electron potential model theory, the ground-state wave function of Na is investigated. The variationally stable procedure of Gao and Starace is then employed to evaluate the static multipolar polarizabilities of Na, and the two-body dispersion coefficients for the Na-Na system. Calculated values show that our results are in general agreement with those previously reported in the literature.

  15. Force-balance model of suppression of multipolar division in cancer cells with extra centrosomes

    NASA Astrophysics Data System (ADS)

    Zhu, Jie

    2013-03-01

    Cancer cells often possess extra centrosomes which have the potential to cause cell death due to catastrophic multipolar division. Many cancer cells, however, are able to escape multipolar mitosis by clustering the extra centrosomes to form bipolar spindles. The mechanism of centrosome clustering is therefore of great interest to the development of anti-cancer drugs because the de-clustering of extra centrosomes provides an appealing way to eliminate cancer cells while keeping healthy cells intact. We present a physical model assuming 1) dynamic centrosomal microtubules interact with chromosomes by both pushing on chromosome arms and pulling along kinetochores; 2) these microtubules interact with force generators associated with actin/adhesion structures at the cell boundary; and 3) motors act on anti-parallel microtubules from different centrosomes. We find via computer simulations that chromosomes tend to aggregate near the cell center while centrosomes can be either clustered to form bipolar spindles or scattered to form multipolar spindles, depending on the strengths of relative forces, cell shape and adhesion geometry. The model predictions agree with data from cells plated on adhesive micropatterns and from biochemically or genetically perturbed cells. Furthermore, our model is able to explain various microtubule distributions in interphase cells on patterned substrates. This work was supported by NSF

  16. RP58 regulates the multipolar-bipolar transition of newborn neurons in the developing cerebral cortex.

    PubMed

    Ohtaka-Maruyama, Chiaki; Hirai, Shinobu; Miwa, Akiko; Heng, Julian Ik-Tsen; Shitara, Hiroshi; Ishii, Rie; Taya, Choji; Kawano, Hitoshi; Kasai, Masataka; Nakajima, Kazunori; Okado, Haruo

    2013-02-21

    Accumulating evidence suggests that many brain diseases are associated with defects in neuronal migration, suggesting that this step of neurogenesis is critical for brain organization. However, the molecular mechanisms underlying neuronal migration remain largely unknown. Here, we identified the zinc-finger transcriptional repressor RP58 as a key regulator of neuronal migration via multipolar-to-bipolar transition. RP58(-/-) neurons exhibited severe defects in the formation of leading processes and never shifted to the locomotion mode. Cre-mediated deletion of RP58 using in utero electroporation in RP58(flox/flox) mice revealed that RP58 functions in cell-autonomous multipolar-to-bipolar transition, independent of cell-cycle exit. Finally, we found that RP58 represses Ngn2 transcription to regulate the Ngn2-Rnd2 pathway; Ngn2 knockdown rescued migration defects of the RP58(-/-) neurons. Our findings highlight the critical role of RP58 in multipolar-to-bipolar transition via suppression of the Ngn2-Rnd2 pathway in the developing cerebral cortex.

  17. Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate.

    PubMed

    Westerlund, Nina; Zdrojewska, Justyna; Padzik, Artur; Komulainen, Emilia; Björkblom, Benny; Rannikko, Emmy; Tararuk, Tanya; Garcia-Frigola, Cristina; Sandholm, Jouko; Nguyen, Laurent; Kallunki, Tuula; Courtney, Michael J; Coffey, Eleanor T

    2011-03-01

    Cell migration is the consequence of the sum of positive and negative regulatory mechanisms. Although appropriate migration of neurons is a principal feature of brain development, the negative regulatory mechanisms remain obscure. We found that JNK1 was highly active in developing cortex and that selective inhibition of JNK in the cytoplasm markedly increased both the frequency of exit from the multipolar stage and radial migration rate and ultimately led to an ill-defined cellular organization. Moreover, regulation of multipolar-stage exit and radial migration in Jnk1(-/-) (also known as Mapk8) mice, resulted from consequential changes in phosphorylation of the microtubule regulator SCG10 (also called stathmin-2). Expression of an SCG10 mutant that mimics the JNK1-phosphorylated form restored normal migration in the brains of Jnk1(-/-) mouse embryos. These findings indicate that the phosphorylation of SCG10 by JNK1 is a fundamental mechanism that governs the transition from the multipolar stage and the rate of neuronal cell movement during cortical development.

  18. Multipolar Effects in the Optical Active Second Harmonic Generation from Sawtooth Chiral Metamaterials

    PubMed Central

    Su, Huimin; Guo, Yuxiang; Gao, Wensheng; Ma, Jie; Zhong, Yongchun; Tam, Wing Yim; Chan, C. T.; Wong, Kam Sing

    2016-01-01

    Based on the facts that chiral molecules response differently to left- and right-handed circular polarized light, chiroptical effects are widely employed for determining structure chirality, detecting enantiomeric excess, or controlling chemical reactions of molecules. Compared to those in natural materials, chiroptical behaviors can be significantly amplified in chiral plasmonic metamaterials due to the concentrated local fields in the structure. The on-going research towards giant chiroptical effects in metamaterial generally focus on optimizing the field-enhancement effects. However, the observed chiroptical effects in metamaterials rely on more complicated factors and various possibilities towards giant chiroptical effects remains unexplored. Here we study the optical-active second harmonic generation (SHG) behaviors in a pair of planar sawtooth gratings with mirror-imaged patterns. Significant multipolar effects were observed in the polarization-dependent SHG curves. We show that the chirality of the nanostructure not only give rise to nonzero chiral susceptibility tensor components within the electric-dipole approximation, but also lead to different levels of multipolar interactions for the two orthogonal circular polarizations that further enhance the nonlinear optical activity of the material. Our results thus indicate novel ways to optimize nonlinear plasmonic structures and achieve giant chiroptical response via multipolar interactions. PMID:26911449

  19. Cytotoxicity of paclitaxel in breast cancer is due to chromosome missegregation on multipolar spindles

    PubMed Central

    Zasadil, Lauren M.; Andersen, Kristen A.; Yeum, Dabin; Rocque, Gabrielle B.; Wilke, Lee G.; Tevaarwerk, Amye J.; Raines, Ronald T.; Burkard, Mark E.; Weaver, Beth A.

    2014-01-01

    The blockbuster chemotherapy drug paclitaxel is widely presumed to cause cell death in tumors as a consequence of mitotic arrest, as it does at concentrations routinely used in cell culture. However, we determine here that paclitaxel levels in primary breast tumors are well below those required to elicit sustained mitotic arrest. Instead, cells in these lower concentrations of drug proceed through mitosis without substantial delay and divide their chromosomes on multipolar spindles, resulting in chromosome missegregation and cell death. Consistent with these cell culture data, the majority of mitotic cells in primary human breast cancers contain multipolar spindles after paclitaxel treatment. Contrary to the previous hypothesis, we find that mitotic arrest is dispensable for tumor regression in patients. These results demonstrate that mitotic arrest is not responsible for the efficacy of paclitaxel, which occurs due to chromosome missegregation on highly abnormal, multipolar spindles. This mechanistic insight may be used to improve selection of future anti-mitotic drugs and to identify a biomarker with which to select patients likely to benefit from paclitaxel. PMID:24670687

  20. Efficacy of multipolar radiofrequency with pulsed magnetic field therapy for the treatment of abdominal cellulite.

    PubMed

    Wanitphakdeedecha, Rungsima; Sathaworawong, Angkana; Manuskiatti, Woraphong; Sadick, Neil S

    2017-08-01

    Cellulite is a metabolic condition, predominately seen in females, that affects the subcutaneous tissue of the posterolateral thighs, buttocks, pelvic region, and abdomen. It is characterized by skin dimpling and lumpiness resembling an orange peel. Despite the wide range of treatment options for patients with cellulite, there is a paucity of empirical data supporting their efficacy. The objective of this study was to evaluate the efficacy of a new-generation multipolar radiofrequency (RF) device for the treatment of cellulite. A multipolar RF device with pulsed magnetic fields was used to treat abdominal cellulite. Twenty-five healthy adult females with stage II or stage III abdominal cellulite underwent 8 weekly treatments. Assessments were performed at baseline and at weeks 1, 4, and 12 following the final treatment. Reduction in subcutaneous thickness in the axial and sagittal plane of the abdomen was observed at 1 week following treatment initiation. Results from self-reported questionnaires revealed a significantly high level of patient satisfaction (60%). Assessments by a blinded investigator at one, four, and twelve weeks after the final treatment demonstrated a significant improvement in cellulite appearance. No adverse effects were reported and the treatment was well tolerated. This study demonstrates the safety, efficacy, and subject satisfaction of multipolar RF with pulsed magnetic field therapy in the treatment of abdominal cellulite.

  1. Progress in Induction Linacs

    SciTech Connect

    Caporaso, G J

    2000-09-27

    This presentation will be a broad survey of progress in induction technology over the past four years. Much work has been done on accelerators for hydrodynamic test radiography and other applications. Solid-state pulsers have been developed which can provide unprecedented flexibility and precision in pulse format and accelerating voltage for both ion and electron induction machines. Induction linacs can now be built which can operate with MHz repetition rates. Solid-state technology has also made possible the development of fast kickers for precision control of high current beams. New insulator technology has been developed which will improve conventional induction linacs in addition to enabling a new class of high gradient induction linacs.

  2. Machine Shop Grinding Machines.

    ERIC Educational Resources Information Center

    Dunn, James

    This curriculum manual is one in a series of machine shop curriculum manuals intended for use in full-time secondary and postsecondary classes, as well as part-time adult classes. The curriculum can also be adapted to open-entry, open-exit programs. Its purpose is to equip students with basic knowledge and skills that will enable them to enter the…

  3. Analysis and design of asymmetrical reluctance machine

    NASA Astrophysics Data System (ADS)

    Harianto, Cahya A.

    Over the past few decades the induction machine has been chosen for many applications due to its structural simplicity and low manufacturing cost. However, modest torque density and control challenges have motivated researchers to find alternative machines. The permanent magnet synchronous machine has been viewed as one of the alternatives because it features higher torque density for a given loss than the induction machine. However, the assembly and permanent magnet material cost, along with safety under fault conditions, have been concerns for this class of machine. An alternative machine type, namely the asymmetrical reluctance machine, is proposed in this work. Since the proposed machine is of the reluctance machine type, it possesses desirable feature, such as near absence of rotor losses, low assembly cost, low no-load rotational losses, modest torque ripple, and rather benign fault conditions. Through theoretical analysis performed herein, it is shown that this machine has a higher torque density for a given loss than typical reluctance machines, although not as high as the permanent magnet machines. Thus, the asymmetrical reluctance machine is a viable and advantageous machine alternative where the use of permanent magnet machines are undesirable.

  4. Energy saving concepts relating to induction generators

    NASA Technical Reports Server (NTRS)

    Nola, F. J.

    1980-01-01

    Energy saving concepts relating to induction generators are presented. The first describes a regenerative scheme using an induction generator as a variable load for prime movers under test is described. A method for reducing losses in induction machines used specifically as wind driven generators is also described.

  5. Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein–Ligand Complexes

    DOE PAGES

    Pollock, Jonathan; Borkin, Dmitry; Lund, George; ...

    2015-08-19

    Multipolar interactions involving fluorine and the protein backbone have been frequently observed in protein–ligand complexes. Such fluorine–backbone interactions may substantially contribute to the high affinity of small molecule inhibitors. Here we found that introduction of trifluoromethyl groups into two different sites in the thienopyrimidine class of menin–MLL inhibitors considerably improved their inhibitory activity. In both cases, trifluoromethyl groups are engaged in short interactions with the backbone of menin. In order to understand the effect of fluorine, we synthesized a series of analogues by systematically changing the number of fluorine atoms, and we determined high-resolution crystal structures of the complexes withmore » menin. Here, we found that introduction of fluorine at favorable geometry for interactions with backbone carbonyls may improve the activity of menin–MLL inhibitors as much as 5- to 10-fold. In order to facilitate the design of multipolar fluorine–backbone interactions in protein–ligand complexes, we developed a computational algorithm named FMAP, which calculates fluorophilic sites in proximity to the protein backbone. We demonstrated that FMAP could be used to rationalize improvement in the activity of known protein inhibitors upon introduction of fluorine. Furthermore, FMAP may also represent a valuable tool for designing new fluorine substitutions and support ligand optimization in drug discovery projects. Analysis of the menin–MLL inhibitor complexes revealed that the backbone in secondary structures is particularly accessible to the interactions with fluorine. Lastly, considering that secondary structure elements are frequently exposed at protein interfaces, we postulate that multipolar fluorine–backbone interactions may represent a particularly attractive approach to improve inhibitors of protein–protein interactions.« less

  6. Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein-Ligand Complexes.

    PubMed

    Pollock, Jonathan; Borkin, Dmitry; Lund, George; Purohit, Trupta; Dyguda-Kazimierowicz, Edyta; Grembecka, Jolanta; Cierpicki, Tomasz

    2015-09-24

    Multipolar interactions involving fluorine and the protein backbone have been frequently observed in protein-ligand complexes. Such fluorine-backbone interactions may substantially contribute to the high affinity of small molecule inhibitors. Here we found that introduction of trifluoromethyl groups into two different sites in the thienopyrimidine class of menin-MLL inhibitors considerably improved their inhibitory activity. In both cases, trifluoromethyl groups are engaged in short interactions with the backbone of menin. In order to understand the effect of fluorine, we synthesized a series of analogues by systematically changing the number of fluorine atoms, and we determined high-resolution crystal structures of the complexes with menin. We found that introduction of fluorine at favorable geometry for interactions with backbone carbonyls may improve the activity of menin-MLL inhibitors as much as 5- to 10-fold. In order to facilitate the design of multipolar fluorine-backbone interactions in protein-ligand complexes, we developed a computational algorithm named FMAP, which calculates fluorophilic sites in proximity to the protein backbone. We demonstrated that FMAP could be used to rationalize improvement in the activity of known protein inhibitors upon introduction of fluorine. Furthermore, FMAP may also represent a valuable tool for designing new fluorine substitutions and support ligand optimization in drug discovery projects. Analysis of the menin-MLL inhibitor complexes revealed that the backbone in secondary structures is particularly accessible to the interactions with fluorine. Considering that secondary structure elements are frequently exposed at protein interfaces, we postulate that multipolar fluorine-backbone interactions may represent a particularly attractive approach to improve inhibitors of protein-protein interactions.

  7. Post-Newtonian factorized multipolar waveforms for spinning, nonprecessing black-hole binaries

    SciTech Connect

    Pan, Yi; Buonanno, Alessandra; Racine, Etienne; Fujita, Ryuichi; Tagoshi, Hideyuki

    2011-03-15

    We generalize the factorized resummation of multipolar waveforms introduced by Damour, Iyer, and Nagar to spinning black holes. For a nonspinning test particle spiraling a Kerr black hole in the equatorial plane, we find that factorized multipolar amplitudes which replace the residual relativistic amplitude f{sub lm} with its lth root, {rho}{sub lm}=f{sub lm}{sup 1/l}, agree quite well with the numerical amplitudes up to the Kerr-spin value q{<=}0.95 for orbital velocities v{<=}0.4. The numerical amplitudes are computed solving the Teukolsky equation with a spectral code. The agreement for prograde orbits and large spin values of the Kerr black-hole can be further improved at high velocities by properly factoring out the lower-order post-Newtonian contributions in {rho}{sub lm}. The resummation procedure results in a better and systematic agreement between numerical and analytical amplitudes (and energy fluxes) than standard Taylor-expanded post-Newtonian approximants. This is particularly true for higher-order modes, such as (2,1), (3,3), (3,2), and (4,4), for which less spin post-Newtonian terms are known. We also extend the factorized resummation of multipolar amplitudes to generic mass-ratio, nonprecessing, spinning black holes. Lastly, in our study we employ new, recently computed, higher-order post-Newtonian terms in several subdominant modes and compute explicit expressions for the half and one-and-half post-Newtonian contributions to the odd-parity (current) and even-parity (odd) multipoles, respectively. Those results can be used to build more accurate templates for ground-based and space-based gravitational-wave detectors.

  8. Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein–Ligand Complexes

    PubMed Central

    2015-01-01

    Multipolar interactions involving fluorine and the protein backbone have been frequently observed in protein–ligand complexes. Such fluorine–backbone interactions may substantially contribute to the high affinity of small molecule inhibitors. Here we found that introduction of trifluoromethyl groups into two different sites in the thienopyrimidine class of menin–MLL inhibitors considerably improved their inhibitory activity. In both cases, trifluoromethyl groups are engaged in short interactions with the backbone of menin. In order to understand the effect of fluorine, we synthesized a series of analogues by systematically changing the number of fluorine atoms, and we determined high-resolution crystal structures of the complexes with menin. We found that introduction of fluorine at favorable geometry for interactions with backbone carbonyls may improve the activity of menin–MLL inhibitors as much as 5- to 10-fold. In order to facilitate the design of multipolar fluorine–backbone interactions in protein–ligand complexes, we developed a computational algorithm named FMAP, which calculates fluorophilic sites in proximity to the protein backbone. We demonstrated that FMAP could be used to rationalize improvement in the activity of known protein inhibitors upon introduction of fluorine. Furthermore, FMAP may also represent a valuable tool for designing new fluorine substitutions and support ligand optimization in drug discovery projects. Analysis of the menin–MLL inhibitor complexes revealed that the backbone in secondary structures is particularly accessible to the interactions with fluorine. Considering that secondary structure elements are frequently exposed at protein interfaces, we postulate that multipolar fluorine–backbone interactions may represent a particularly attractive approach to improve inhibitors of protein–protein interactions. PMID:26288158

  9. Multipolar moments of weak lensing signal around clusters. Weighing filaments in harmonic space

    NASA Astrophysics Data System (ADS)

    Gouin, C.; Gavazzi, R.; Codis, S.; Pichon, C.; Peirani, S.; Dubois, Y.

    2017-09-01

    Context. Upcoming weak lensing surveys such as Euclid will provide an unprecedented opportunity to quantify the geometry and topology of the cosmic web, in particular in the vicinity of lensing clusters. Aims: Understanding the connectivity of the cosmic web with unbiased mass tracers, such as weak lensing, is of prime importance to probe the underlying cosmology, seek dynamical signatures of dark matter, and quantify environmental effects on galaxy formation. Methods: Mock catalogues of galaxy clusters are extracted from the N-body PLUS simulation. For each cluster, the aperture multipolar moments of the convergence are calculated in two annuli (inside and outside the virial radius). By stacking their modulus, a statistical estimator is built to characterise the angular mass distribution around clusters. The moments are compared to predictions from perturbation theory and spherical collapse. Results: The main weakly chromatic excess of multipolar power on large scales is understood as arising from the contraction of the primordial cosmic web driven by the growing potential well of the cluster. Besides this boost, the quadrupole prevails in the cluster (ellipsoidal) core, while at the outskirts, harmonic distortions are spread on small angular modes, and trace the non-linear sharpening of the filamentary structures. Predictions for the signal amplitude as a function of the cluster-centric distance, mass, and redshift are presented. The prospects of measuring this signal are estimated for current and future lensing data sets. Conclusions: The Euclid mission should provide all the necessary information for studying the cosmic evolution of the connectivity of the cosmic web around lensing clusters using multipolar moments and probing unique signatures of, for example, baryons and warm dark matter.

  10. Multipolar electromagnetic fields around neutron stars: exact vacuum solutions and related properties

    NASA Astrophysics Data System (ADS)

    Pétri, J.

    2015-06-01

    The magnetic field topology in the surrounding of neutron stars is one of the key questions in pulsar magnetospheric physics. A very extensive literature exists about the assumption of a dipolar magnetic field but very little progress has been made in attempts to include multipolar components in a self-consistent way. In this paper, we study the effect of multipolar electromagnetic fields anchored in the star. We give exact analytical solutions in closed form for any order l and apply them to the retarded point quadrupole (l = 2), hexapole (l = 3) and octopole (l = 4), a generalization of the retarded point dipole (l = 1). We also compare the Poynting flux from each multipole and show that the spin-down luminosity depends on the ratio R/rL, R being the neutron star radius and rL the light-cylinder radius. Therefore the braking index also depends on R/rL. As such multipole fields possess very different topology, most importantly smaller length scales compared to the dipolar field, especially close to the neutron star, we investigate the deformation of the polar caps induced by these multipolar fields. Such fields could have a strong impact on the interpretation of the pulsed radio emission suspected to emanate from these polar caps as well as on the inferred geometry deduced from the high-energy light-curve fitting and on the magnetic field strength. Discrepancies between the two-pole caustic model and our new multipole caustic model are emphasized with the quadrupole field. To this respect, we demonstrate that working with only a dipole field can be very misleading.

  11. Rational Design of Orthogonal Multipolar Interactions with Fluorine in Protein–Ligand Complexes

    SciTech Connect

    Pollock, Jonathan; Borkin, Dmitry; Lund, George; Purohit, Trupta; Dyguda-Kazimierowicz, Edyta; Grembecka, Jolanta; Cierpicki, Tomasz

    2015-08-19

    Multipolar interactions involving fluorine and the protein backbone have been frequently observed in protein–ligand complexes. Such fluorine–backbone interactions may substantially contribute to the high affinity of small molecule inhibitors. Here we found that introduction of trifluoromethyl groups into two different sites in the thienopyrimidine class of menin–MLL inhibitors considerably improved their inhibitory activity. In both cases, trifluoromethyl groups are engaged in short interactions with the backbone of menin. In order to understand the effect of fluorine, we synthesized a series of analogues by systematically changing the number of fluorine atoms, and we determined high-resolution crystal structures of the complexes with menin. Here, we found that introduction of fluorine at favorable geometry for interactions with backbone carbonyls may improve the activity of menin–MLL inhibitors as much as 5- to 10-fold. In order to facilitate the design of multipolar fluorine–backbone interactions in protein–ligand complexes, we developed a computational algorithm named FMAP, which calculates fluorophilic sites in proximity to the protein backbone. We demonstrated that FMAP could be used to rationalize improvement in the activity of known protein inhibitors upon introduction of fluorine. Furthermore, FMAP may also represent a valuable tool for designing new fluorine substitutions and support ligand optimization in drug discovery projects. Analysis of the menin–MLL inhibitor complexes revealed that the backbone in secondary structures is particularly accessible to the interactions with fluorine. Lastly, considering that secondary structure elements are frequently exposed at protein interfaces, we postulate that multipolar fluorine–backbone interactions may represent a particularly attractive approach to improve inhibitors of protein–protein interactions.

  12. Optical Photometry of BY Cam Modeled Using a Multipolar Magnetic Field Structure

    NASA Astrophysics Data System (ADS)

    Morales, John; Mason, P. A.; Zhilkin, A.; Bisikalo, D. V.; Robinson, E. L.

    2014-01-01

    We present new high-speed broad-band optical photometry of the asynchronous polar (magnetic cataclysmic variable) BY Cam. Observations were obtained at the 2.1-m Otto Struve Telescope of McDonald observatory with 3s integration times. In an attempt to understand the complex changes in accretion flow geometry, we performed full 3D MHD simulations assuming a variety of white dwarf magnetic field structures including both aligned and non-aligned dipole plus quadrupole field components. We compare model predictions with photometry and various phases of the beat cycle and find that synthetic light curves derived from a multipolar field structure are consistent with the optical photometry.

  13. Effective medium multipolar tensor analysis of second-harmonic generation from metal nanoparticles

    NASA Astrophysics Data System (ADS)

    Zdanowicz, Mariusz; Kujala, Sami; Husu, Hannu; Kauranen, Martti

    2011-02-01

    We present a detailed multipolar tensor analysis of second-harmonic (SH) generation from arrays of L-shaped gold nanoparticles. We define three effective nonlinear tensors, which include electric dipoles only (Aeee) and lowest-order magnetic (and quadrupole) effects at the fundamental (Aeem) and the SH (Amee) frequency. The components of the various tensors are distinguished through their different transformations as the experimental geometry is varied. The response is dominated by electric-dipole effects. However, the higher multipoles also play a significant role and are more important at the fundamental frequency than at the SH frequency. The results correlate well with the particles' plasmonic resonances and symmetry rules.

  14. Database machines

    NASA Technical Reports Server (NTRS)

    Stiefel, M. L.

    1983-01-01

    The functions and performance characteristics of data base machines (DBM), including machines currently being studied in research laboratories and those currently offered on a commerical basis are discussed. The cost/benefit considerations that must be recognized in selecting a DBM are discussed, as well as the future outlook for such machines.

  15. The Development of the Multipolar Magnesium Cell: A Case History of International Cooperation in a Competitive World

    NASA Astrophysics Data System (ADS)

    Sivilotti, Olivo G.

    The author conceived the first multipolar magnesium electrolytic cell in the late 1970s, in order to offset the impact of an 80kA monopolar cell developed in cooperation with Osaka Titanium Company (OTC) being licensed by Alcan to a major competitor of OTC. During the 1980s the commercial value of the multipolar magnesium cell technology was established. The 1990s saw significant further progress by OTC, while attempts by Alcan to commercialize it in magnesium production plants met with technical difficulties and failure, due primarily to the lack of magnesium chloride feed of adequate quality. Now the author plans to commercialize a new multipolar cell design with a target productivity of 8-10 tons/day and a unit power consumption of 8.5-10 KWHR/kg of magnesium.

  16. MEG (Magnetoencephalography) multipolar modeling of distributed sources using RAP-MUSIC (Recursively Applied and Projected Multiple Signal Characterization)

    SciTech Connect

    Mosher, J. C.; Baillet, S.; Jerbi, K.; Leahy, R. M.

    2001-01-01

    We describe the use of truncated multipolar expansions for producing dynamic images of cortical neural activation from measurements of the magnetoencephalogram. We use a signal-subspace method to find the locations of a set of multipolar sources, each of which represents a region of activity in the cerebral cortex. Our method builds up an estimate of the sources in a recursive manner, i.e. we first search for point current dipoles, then magnetic dipoles, and finally first order multipoles. The dynamic behavior of these sources is then computed using a linear fit to the spatiotemporal data. The final step in the procedure is to map each of the multipolar sources into an equivalent distributed source on the cortical surface. The method is illustrated through an application to epileptic interictal MEG data.

  17. Properties of liquid water from a systematic refinement of a high-rank multipolar electrostatic potential.

    PubMed

    Shaik, Majeed S; Liem, Steven Y; Popelier, Paul L A

    2010-05-07

    We build on previous work [S. Y. Liem and P. L. A. Popelier, J. Chem. Theory Comput. 4, 353 (2008)], where for the first time, a high-rank multipolar electrostatic potential was used in molecular dynamics simulations of liquid water at a wide range of pressures and temperatures, and using a multipolar Ewald summation. Water is represented as a rigid body, with atomic multipole moments defined by quantum chemical topology partitioning its gas phase electron density. The effect of the level of theory on the local structure of liquid water is systematically addressed. Values for Lennard-Jones (LJ) parameters are optimized, for both oxygen and hydrogen atoms, against bulk properties. The best LJ parameters were then used in a set of simulations at 30 different temperatures (1 atm) and another set at 11 different pressures (at 298 K). Inclusion of the hydrogen LJ parameters significantly increases the self-diffusion coefficient. The behavior of bulk properties was studied and the local water structure analyzed by both radial and spatial distribution functions. Comparisons with familiar point-charge potentials, such as TIP3P, TIP4P, TIP5P, and simple point charge, show the benefits of multipole moments.

  18. Effects of Multipolar Radiofrequency and Pulsed Electromagnetic Field Treatment for Face and Neck Rejuvenation

    PubMed Central

    de Oliveira, Thais Cristina Ferraz; Rocha, Sheyla de Fatima Soares; Ramos, Daniel Gontijo; Ramos, Camila Gontijo; Carvalho, Michelle Vanessa dos Anjos

    2017-01-01

    Skin aging is a gradual process that leads to wrinkle formation, laxity, and overall changes in skin appearance. In recent years, the demands to noninvasive treatments for facial rejuvenation increased, along with a variety of technologies and devices, such as radiofrequency. The present study aimed to evaluate the clinical effects of a multipolar radiofrequency and pulsed electromagnetic field treatment for face and neck rejuvenation. Eleven patients with mild to moderate grades of photoaging underwent eight radiofrequency and pulsed electromagnetic field treatment sessions, once a week. Clinical photographs were taken before and a week after the end of the treatment, and improvement of facial skin parameters was evaluated by two different investigators. Significant improvement in skin laxity was observed in all eleven patients (100%). Improvement in facial contour was noted in 73% and 100% of patients when analyzed by investigators A and B, respectively. The score for overall improvement in skin condition was 3 ± 0.78 for investigator A and 3.6 ± 0.67 for investigator B. All patients were satisfied with the procedure and noted significant improvement in the skin. The combined multipolar radiofrequency and pulsed electromagnetic field device is effective and safe for treatment of aged skin in Brazilian patients. PMID:28373880

  19. An axosomatic and axodendritic multipolar neuron in the lizard cerebral cortex.

    PubMed Central

    Bernabeu, A; Martinez-Guijarro, F J; de la Iglesia, J A; Lopez-Garcia, C

    1994-01-01

    The morphology and synaptic organisation of a type of multipolar neuron of the lizard cerebral cortex were studied by Golgi impregnation, intracellular injection of horseradish peroxidase, electron microscopy, and immunocytochemistry. It is a GABA-immunoreactive interneuron and most likely parvalbumin-immunoreactive. Its conspicuous axonal arbor is characterised by an initial segment arising from the soma or from a juxtasomatic dendritic segment. The initial axon segment ramifies and gives rise to thick myelinated segments that terminate in short unmyelinated branches studded with thick boutons 'en passant' that (1) make axosomatic synapses on bipyramidal neuronal somata and (2) synapse on initial apical dendritic segments of bipyramidal neurons forming climbing-like cartridges. The dendrites extend throughout the thickness of the cortex, receiving synaptic input from a variety of sources of which the most prominent is that of zinc-positive boutons coming from granule cells of the medial cortex. According to its synaptology, this interneuron may play a role in regulating the activity of bipyramidal neurons by both feed-forward and feed-back inhibition mechanisms. From a comparative standpoint, it may be related to the sparsely spiny or nonspiny multipolar neurons of the stratum oriens of the mammalian hippocampus. Images Fig. 1 Fig. 4 Fig. 6 Fig. 7 Fig. 8 PMID:7928645

  20. Induction motor control

    NASA Astrophysics Data System (ADS)

    Hansen, Irving G.

    Electromechanical actuators developed to date have commonly ultilized permanent magnet (PM) synchronous motors. More recently switched reluctance (SR) motors have been advocated due to their robust characteristics. Implications of work which utilized induction motors and advanced control techniques are discussed. When induction motors are operated from an energy source capable of controlling voltages and frequencies independently, drive characteristics are obtained which are superior to either PM or SR motors. By synthesizing the machine frequency from a high-frequency carrier (nominally 20 kHz), high efficiencies, low distortion, and rapid torque response are available. At this time multiple horsepower machine drives were demonstrated, and work is on-going to develop a 20 hp average, 40 hp peak class of aerospace actuators. This effort is based upon high-frequency power distribution and management techniques developed by NASA for Space Station Freedom.

  1. Induction motor control

    NASA Technical Reports Server (NTRS)

    Hansen, Irving G.

    1990-01-01

    Electromechanical actuators developed to date have commonly ultilized permanent magnet (PM) synchronous motors. More recently switched reluctance (SR) motors have been advocated due to their robust characteristics. Implications of work which utilized induction motors and advanced control techniques are discussed. When induction motors are operated from an energy source capable of controlling voltages and frequencies independently, drive characteristics are obtained which are superior to either PM or SR motors. By synthesizing the machine frequency from a high-frequency carrier (nominally 20 kHz), high efficiencies, low distortion, and rapid torque response are available. At this time multiple horsepower machine drives were demonstrated, and work is on-going to develop a 20 hp average, 40 hp peak class of aerospace actuators. This effort is based upon high-frequency power distribution and management techniques developed by NASA for Space Station Freedom.

  2. Induction motor control

    NASA Technical Reports Server (NTRS)

    Hansen, Irving G.

    1990-01-01

    Electromechanical actuators developed to date have commonly utilized permanent magnet (PM) synchronous motors. More recently switched reluctance (SR) motors have been advocated due to their robust characteristics. Implications of work which utilizes induction motors and advanced control techniques are discussed. When induction motors are operated from an energy source capable of controlling voltages and frequencies independently, drive characteristics are obtained which are superior to either PM or SR motors. By synthesizing the machine frequency from a high frequency carrier (nominally 20 kHz), high efficiencies, low distortion, and rapid torque response are available. At this time multiple horsepower machine drives were demonstrated, and work is on-going to develop a 20 hp average, 40 hp peak class of aerospace actuators. This effort is based upon high frequency power distribution and management techniques developed by NASA for Space Station Freedom.

  3. Induction motor control

    NASA Technical Reports Server (NTRS)

    Hansen, Irving G.

    1990-01-01

    Electromechanical actuators developed to date have commonly ultilized permanent magnet (PM) synchronous motors. More recently switched reluctance (SR) motors have been advocated due to their robust characteristics. Implications of work which utilized induction motors and advanced control techniques are discussed. When induction motors are operated from an energy source capable of controlling voltages and frequencies independently, drive characteristics are obtained which are superior to either PM or SR motors. By synthesizing the machine frequency from a high-frequency carrier (nominally 20 kHz), high efficiencies, low distortion, and rapid torque response are available. At this time multiple horsepower machine drives were demonstrated, and work is on-going to develop a 20 hp average, 40 hp peak class of aerospace actuators. This effort is based upon high-frequency power distribution and management techniques developed by NASA for Space Station Freedom.

  4. Integrated Inverter For Driving Multiple Electric Machines

    DOEpatents

    Su, Gui-Jia [Knoxville, TN; Hsu, John S [Oak Ridge, TN

    2006-04-04

    An electric machine drive (50) has a plurality of inverters (50a, 50b) for controlling respective electric machines (57, 62), which may include a three-phase main traction machine (57) and two-phase accessory machines (62) in a hybrid or electric vehicle. The drive (50) has a common control section (53, 54) for controlling the plurality of inverters (50a, 50b) with only one microelectronic processor (54) for controlling the plurality of inverters (50a, 50b), only one gate driver circuit (53) for controlling conduction of semiconductor switches (S1-S10) in the plurality of inverters (50a, 50b), and also includes a common dc bus (70), a common dc bus filtering capacitor (C1) and a common dc bus voltage sensor (67). The electric machines (57, 62) may be synchronous machines, induction machines, or PM machines and may be operated in a motoring mode or a generating mode.

  5. Superconducting Electric Machines for Ship Propulsion.

    DTIC Science & Technology

    1977-02-14

    ship propulsion applications. These concepts evolved from previous work at MIT on superconducting AC machines. The superconducting machines considered were: (1) multipole, low-speed motors, (2) torque compensated motors, (3) high-speed generator, (4) rotating air-gap armature induction motor, (5) thyristor switched AC motors. The first four machine types were studied theoretically while experimental models were constructed of the last two. Preliminary designs were completed...of the five mahcines for an appropriate ship ... propulsion application. In

  6. Miniature Gas-Circulating Machine

    NASA Technical Reports Server (NTRS)

    Swift, Walter L.; Valenzuela, Javier A.; Sixsmith, Herbert; Nutt, William E.

    1993-01-01

    Proposed gas-circulating machine consists essentially of centrifugal pump driven by induction motor. Noncontact bearings suppress wear and contamination. Used to circulate helium (or possibly hydrogen or another gas) in regeneration sorption-compressor refrigeration system aboard spacecraft. Also proves useful in terrestrial applications in which long life, reliability, and low contamination essential.

  7. Electric machine

    DOEpatents

    El-Refaie, Ayman Mohamed Fawzi [Niskayuna, NY; Reddy, Patel Bhageerath [Madison, WI

    2012-07-17

    An interior permanent magnet electric machine is disclosed. The interior permanent magnet electric machine comprises a rotor comprising a plurality of radially placed magnets each having a proximal end and a distal end, wherein each magnet comprises a plurality of magnetic segments and at least one magnetic segment towards the distal end comprises a high resistivity magnetic material.

  8. Nesting-driven multipolar order in CeB6 from photoemission tomography

    NASA Astrophysics Data System (ADS)

    Koitzsch, A.; Heming, N.; Knupfer, M.; Büchner, B.; Portnichenko, P. Y.; Dukhnenko, A. V.; Shitsevalova, N. Y.; Filipov, V. B.; Lev, L. L.; Strocov, V. N.; Ollivier, J.; Inosov, D. S.

    2016-03-01

    Some heavy fermion materials show so-called hidden-order phases which are invisible to many characterization techniques and whose microscopic origin remained controversial for decades. Among such hidden-order compounds, CeB6 is of model character due to its simple electronic configuration and crystal structure. Apart from more conventional antiferromagnetism, it shows an elusive phase at low temperatures, which is commonly associated with multipolar order. Here we show that this phase roots in a Fermi surface instability. This conclusion is based on a full 3D tomographic sampling of the electronic structure by angle-resolved photoemission and comparison with inelastic neutron scattering data. The hidden order is mediated by itinerant electrons. Our measurements will serve as a paradigm for the investigation of hidden-order phases in f-electron systems, but also generally for situations where the itinerant electrons drive orbital or spin order.

  9. Nesting-driven multipolar order in CeB6 from photoemission tomography.

    PubMed

    Koitzsch, A; Heming, N; Knupfer, M; Büchner, B; Portnichenko, P Y; Dukhnenko, A V; Shitsevalova, N Y; Filipov, V B; Lev, L L; Strocov, V N; Ollivier, J; Inosov, D S

    2016-03-15

    Some heavy fermion materials show so-called hidden-order phases which are invisible to many characterization techniques and whose microscopic origin remained controversial for decades. Among such hidden-order compounds, CeB6 is of model character due to its simple electronic configuration and crystal structure. Apart from more conventional antiferromagnetism, it shows an elusive phase at low temperatures, which is commonly associated with multipolar order. Here we show that this phase roots in a Fermi surface instability. This conclusion is based on a full 3D tomographic sampling of the electronic structure by angle-resolved photoemission and comparison with inelastic neutron scattering data. The hidden order is mediated by itinerant electrons. Our measurements will serve as a paradigm for the investigation of hidden-order phases in f-electron systems, but also generally for situations where the itinerant electrons drive orbital or spin order.

  10. Nesting-driven multipolar order in CeB6 from photoemission tomography

    PubMed Central

    Koitzsch, A.; Heming, N.; Knupfer, M.; Büchner, B.; Portnichenko, P. Y.; Dukhnenko, A. V; Shitsevalova, N. Y.; Filipov, V. B.; Lev, L. L.; Strocov, V. N.; Ollivier, J.; Inosov, D. S.

    2016-01-01

    Some heavy fermion materials show so-called hidden-order phases which are invisible to many characterization techniques and whose microscopic origin remained controversial for decades. Among such hidden-order compounds, CeB6 is of model character due to its simple electronic configuration and crystal structure. Apart from more conventional antiferromagnetism, it shows an elusive phase at low temperatures, which is commonly associated with multipolar order. Here we show that this phase roots in a Fermi surface instability. This conclusion is based on a full 3D tomographic sampling of the electronic structure by angle-resolved photoemission and comparison with inelastic neutron scattering data. The hidden order is mediated by itinerant electrons. Our measurements will serve as a paradigm for the investigation of hidden-order phases in f-electron systems, but also generally for situations where the itinerant electrons drive orbital or spin order. PMID:26976632

  11. Output of acoustical sources. [effects of structural elements and background flow on immobile multipolar point radiation

    NASA Technical Reports Server (NTRS)

    Levine, H.

    1980-01-01

    Acoustic radiation from a source, here viewed as an immobile point singularity with periodic strength and a given multipolar nature, is affected by the presence of nearly structural elements (e.g., rigid or impedance surfaces) as well as that of a background flow in the medium. An alternative to the conventional manner of calculating the net source output by integrating the energy flux over a distant control surface is described; this involves a direct evaluation of the secondary wavefunction at the position of the primary source and obviates the need for a (prospectively difficult) flux integration. Various full and half-planar surface configurations with an adjacent source are analyzed in detail, and the explicit results obtained, in particular, for the power factor of a dipole brings out a substantial rise in its output as the source nears the sharp edge of a half-plane.

  12. Output of acoustical sources. [effects of structural elements and background flow on immobile multipolar point radiation

    NASA Technical Reports Server (NTRS)

    Levine, H.

    1980-01-01

    Acoustic radiation from a source, here viewed as an immobile point singularity with periodic strength and a given multipolar nature, is affected by the presence of nearly structural elements (e.g., rigid or impedance surfaces) as well as that of a background flow in the medium. An alternative to the conventional manner of calculating the net source output by integrating the energy flux over a distant control surface is described; this involves a direct evaluation of the secondary wavefunction at the position of the primary source and obviates the need for a (prospectively difficult) flux integration. Various full and half-planar surface configurations with an adjacent source are analyzed in detail, and the explicit results obtained, in particular, for the power factor of a dipole brings out a substantial rise in its output as the source nears the sharp edge of a half-plane.

  13. Characterizing forest stands with multi-incidence angle and multi-polarized SAR data

    NASA Technical Reports Server (NTRS)

    Hoffer, R. M.; Lozano-Garcia, D. F.; Gillespie, D. D.

    1987-01-01

    The potential for using HH-polarized L-band SAR data obtained at different incidence angles from satellite altitudes to identify and map different forest cover types and stand density classes is studied. Reasonably accurate results are obtained if the speckle characteristics of the data are suppressed by low-pass spatial filters and a contextual classification algorithm. Multipolarized L-band SAR data obtained from aircraft altitudes over the same test site are also analyzed to assess the relationships between polarization and forest stand characteristics. It is found that incidence angle controls, to a very large extent, the characteristics of the data and the type of information that can be obtained from L-band, HH-polarized satellite SAR data. Cross-polarization of L-band SAR data enhances and differentiates various forest stand characteristics which cannot be defined using only the like-polarized data, and vice-versa.

  14. FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.

    PubMed

    La Fata, Giorgio; Gärtner, Annette; Domínguez-Iturza, Nuria; Dresselaers, Tom; Dawitz, Julia; Poorthuis, Rogier B; Averna, Michele; Himmelreich, Uwe; Meredith, Rhiannon M; Achsel, Tilmann; Dotti, Carlos G; Bagni, Claudia

    2014-12-01

    Deficiencies in fragile X mental retardation protein (FMRP) are the most common cause of inherited intellectual disability, fragile X syndrome (FXS), with symptoms manifesting during infancy and early childhood. Using a mouse model for FXS, we found that Fmrp regulates the positioning of neurons in the cortical plate during embryonic development, affecting their multipolar-to-bipolar transition (MBT). We identified N-cadherin, which is crucial for MBT, as an Fmrp-regulated target in embryonic brain. Furthermore, spontaneous network activity and high-resolution brain imaging revealed defects in the establishment of neuronal networks at very early developmental stages, further confirmed by an unbalanced excitatory and inhibitory network. Finally, reintroduction of Fmrp or N-cadherin in the embryo normalized early postnatal neuron activity. Our findings highlight the critical role of Fmrp in the developing cerebral cortex and might explain some of the clinical features observed in patients with FXS, such as alterations in synaptic communication and neuronal network connectivity.

  15. An improved experimental databank of transferable multipolar atom models--ELMAM2. Construction details and applications.

    PubMed

    Domagała, Sławomir; Fournier, Bertrand; Liebschner, Dorothee; Guillot, Benoît; Jelsch, Christian

    2012-05-01

    ELMAM2 is a generalized and improved library of experimentally derived multipolar atom types. The previously published ELMAM database is restricted mostly to protein atoms. The current database is extended to common functional groups encountered in organic molecules and is based on optimized local axes systems taking into account the local pseudosymmetry of the molecular fragment. In this approach, the symmetry-restricted multipoles have zero populations, while others take generally significant values. The various applications of the database are described. The deformation electron densities, electrostatic potentials and interaction energies calculated for several tripeptides and aromatic molecules are calculated using ELMAM2 electron-density parameters and compared with the former ELMAM database and density functional theory calculations.

  16. Multifrequency, Multipolarization External Calibration of the SIR-C/X-SAR Radars

    NASA Technical Reports Server (NTRS)

    Freeman, Anthony; Sarabandi, K.

    1996-01-01

    Progress and the future plans for the following objectives are discussed: (1) Assess the accuracy at which the SIR-C/X-SAR standard data products can be calibrated through the use of ground calibrators to estimate the end-to-end system polarization calibration constants (or distortion parameters) and incorporate the constants into the data processing; (2) Study the cross-calibration between three multipolarization systems: SIR-C, the National Aeronautics and Space Administration/Jet Propulsion Laboratory (NASA/JPL) DC-8 SAR, and the University of Michigan ground-based polarimetric scatterometer; (3) Evaluate the calibration "stability" of SIR-C/X-SAR (measured by variations in the calibration constants) over the range swath width and over a specified distance in azimuth. Variations over a 12-hour period (between ascending and descending passes) will also be studied; and (4) Develop a cost-effective calibration plan including development of inexpensive polarimetric active calibrators.

  17. Estimation of Soil Moisture with L-band Multi-polarization Radar

    NASA Technical Reports Server (NTRS)

    Shi, J.; Chen, K. S.; Kim, Chung-Li Y.; Van Zyl, J. J.; Njoku, E.; Sun, G.; O'Neill, P.; Jackson, T.; Entekhabi, D.

    2004-01-01

    Through analyses of the model simulated data-base, we developed a technique to estimate surface soil moisture under HYDROS radar sensor (L-band multi-polarizations and 40deg incidence) configuration. This technique includes two steps. First, it decomposes the total backscattering signals into two components - the surface scattering components (the bare surface backscattering signals attenuated by the overlaying vegetation layer) and the sum of the direct volume scattering components and surface-volume interaction components at different polarizations. From the model simulated data-base, our decomposition technique works quit well in estimation of the surface scattering components with RMSEs of 0.12,0.25, and 0.55 dB for VV, HH, and VH polarizations, respectively. Then, we use the decomposed surface backscattering signals to estimate the soil moisture and the combined surface roughness and vegetation attenuation correction factors with all three polarizations.

  18. The resveratrol analogue trimethoxystilbene inhibits cancer cell growth by inducing multipolar cell mitosis.

    PubMed

    Traversi, Gianandrea; Fiore, Mario; Percario, Zulema; Degrassi, Francesca; Cozzi, Renata

    2017-03-01

    Natural compounds are extensively studied for their potential use in traditional and non-traditional medicine. Several natural and synthetic Resveratrol analogues have shown interesting biological activities in the field of cancer chemoprevention. In the present study, we have focused on the ability of Resveratrol and two methoxylated derivatives (Trimethoxystilbene and Pterostilbene) to inhibit human cancer cell growth particularly analyzing their ability to interfere with tubulin dynamics at mitosis. We show that Trimethoxystilbene, differently from Resveratrol and Pterostilbene, alters microtubule polymerization dynamics in HeLa cells specifically inducing multipolar spindles and mitotic arrest coupled to a reduction of cell growth and an increase in apoptotic death by mitotic catastrophe. This work demonstrates that the structural modification of Rsv causes substantial changes in the mechanism of action of the derivatives. The presence of three extra methyl groups renders Trimethoxy very efficient in impairing cell proliferation by inducing mitotic catastrophe in cancer cells. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  19. Comparisons of wind speed retrieval methods on C-band multi-polarization SAR measurements

    NASA Astrophysics Data System (ADS)

    Ren, Lin; Yang, Jingsong; Zheng, Gang; Wang, Juan; Wang, Difeng

    2014-10-01

    This paper compares the wind speed retrieval methods on C-band multi-polarization SAR measurements to find out the most appropriate one for each polarization data. The RADARSAT-2 SAR quad-polarization (VV+HH+VH+HV) data and NDBC buoy wind data were collocated. For VVpolarization, the retrieved wind speed are compared among four geophysical model function (GMF). For HH polarization, the retrieved wind speed are compared among four polarization ratio model (PR) based on CMOD5 GMF. For VH polarization, the retrieved wind speed are compared between two linear models. Comparisons show all of three polarimetric SAR data have the ability of retrieving wind speed. Based on the error analysis, the commendatory methods are proposed for each polarization.

  20. Phonon Dynamics and Multipolar Isomorphic Transition in β-Pyrochlore KOs2O6

    NASA Astrophysics Data System (ADS)

    Hattori, Kazumasa

    2011-02-01

    We investigate with a microscopic model anharmonic K-cation oscillation observed by neutron experiments in β-pyrochlore superconductor KOs2O6, which also shows a mysterious first-order structural transition at Tp = 7.5 K. We have identified a set of microscopic model parameters that successfully reproduce the observed tem perature dependence and the superconducting transition temperature. Considering changes in the parameters at Tp, we can explain puzzling experimental results about electron--phonon coupling and neutron data. Our analysis demonstrates that the first-order transition is multipolar transition driven by the octupolar component of K-cation oscillations. The octupole moment does not change the symmetry and is characteristic to noncentrosymmetric K-cation potential.

  1. The multiple functions of T stellate/multipolar/chopper cells in the ventral cochlear nucleus.

    PubMed

    Oertel, Donata; Wright, Samantha; Cao, Xiao-Jie; Ferragamo, Michael; Bal, Ramazan

    2011-06-01

    Acoustic information is brought to the brain by auditory nerve fibers, all of which terminate in the cochlear nuclei, and is passed up the auditory pathway through the principal cells of the cochlear nuclei. A population of neurons variously known as T stellate, type I multipolar, planar multipolar, or chopper cells forms one of the major ascending auditory pathways through the brainstem. T Stellate cells are sharply tuned; as a population they encode the spectrum of sounds. In these neurons, phasic excitation from the auditory nerve is made more tonic by feedforward excitation, coactivation of inhibitory with excitatory inputs, relatively large excitatory currents through NMDA receptors, and relatively little synaptic depression. The mechanisms that make firing tonic also obscure the fine structure of sounds that is represented in the excitatory inputs from the auditory nerve and account for the characteristic chopping response patterns with which T stellate cells respond to tones. In contrast with other principal cells of the ventral cochlear nucleus (VCN), T stellate cells lack a low-voltage-activated potassium conductance and are therefore sensitive to small, steady, neuromodulating currents. The presence of cholinergic, serotonergic and noradrenergic receptors allows the excitability of these cells to be modulated by medial olivocochlear efferent neurons and by neuronal circuits associated with arousal. T Stellate cells deliver acoustic information to the ipsilateral dorsal cochlear nucleus (DCN), ventral nucleus of the trapezoid body (VNTB), periolivary regions around the lateral superior olivary nucleus (LSO), and to the contralateral ventral lemniscal nuclei (VNLL) and inferior colliculus (IC). It is likely that T stellate cells participate in feedback loops through both medial and lateral olivocochlear efferent neurons and they may be a source of ipsilateral excitation of the LSO.

  2. The Fate of Chrysotile-Induced Multipolar Mitosis and Aneuploid Population in Cultured Lung Cancer Cells

    PubMed Central

    de Araujo Cortez, Beatriz; Quassollo, Gonzalo; Caceres, Alfredo; Machado-Santelli, Glaucia Maria

    2011-01-01

    Chrysotile is one of the six types of asbestos, and it is the only one that can still be commercialized in many countries. Exposure to other types of asbestos has been associated with serious diseases, such as lung carcinomas and pleural mesotheliomas. The association of chrysotile exposure with disease is controversial. However, in vitro studies show the mutagenic potential of chrysotile, which can induce DNA and cell damage. The present work aimed to analyze alterations in lung small cell carcinoma cultures after 48 h of chrysotile exposure, followed by 2, 4 and 8 days of recovery in fiber-free culture medium. Some alterations, such as aneuploid cell formation, increased number of cells in G2/M phase and cells in multipolar mitosis were observed even after 8 days of recovery. The presence of chrysotile fibers in the cell cultures was detected and cell morphology was observed by laser scanning confocal microscopy. After 4 and 8 days of recovery, only a few chrysotile fragments were present in some cells, and the cellular morphology was similar to that of control cells. Cells transfected with the GFP-tagged α-tubulin plasmid were treated with chrysotile for 24 or 48 h and cells in multipolar mitosis were observed by time-lapse microscopy. Fates of these cells were established: retention in metaphase, cell death, progression through M phase generating more than two daughter cells or cell fusion during telophase or cytokinesis. Some of them were related to the formation of aneuploid cells and cells with abnormal number of centrosomes. PMID:21483691

  3. Spatial Restriction of Neural Activation Using Focused Multipolar Stimulation With a Retinal Prosthesis.

    PubMed

    Spencer, Thomas C; Fallon, James B; Thien, Patrick C; Shivdasani, Mohit N

    2016-06-01

    The resolution provided by present state-of-the-art retinal prostheses is severely limiting for recipients, partly due to the broad spread of activation in the retina in response to monopolar (MP) electrical stimulation. Focused multipolar (FMP) stimulation has been shown to restrict neural activation in the cochlea compared to MP stimulation. We extended the FMP stimulation technique to a two-dimensional electrode array and compared its efficacy to MP and hexapolar (HP) stimulation in the retina. Normally-sighted cats (n = 6) were implanted with a suprachoroidal electrode array containing 42 electrodes. Multichannel multiunit spiking activity was recorded from the visual cortex in response to MP, HP, and FMP retinal stimulation. When inferring retinal spread using voltage recordings off the stimulating array, FMP stimulation showed significantly reduced voltages in regions surrounding the primary stimulating electrode. When measuring the retinal and cortical selectivity of neural responses, FMP and HP stimulation showed significantly higher selectivity compared to MP stimulation (separate 2-way ANOVAs, P < 0.05). However, the lowest cortical thresholds for each stimulating electrode were higher for FMP and HP compared to MP stimulation (1-way ANOVA, P < 0.001). No significant differences were observed between FMP and HP stimulation in any measures. Focused multipolar and HP stimulation using a two-dimensional array are promising techniques to reduce the spread of activation for a retinal prosthesis. Clinical application would be expected to result in smaller phosphenes; thus, reducing phosphene overlap between electrodes and increasing the resolution at the expense of higher thresholds for activation.

  4. Evolution of the mirror machine

    SciTech Connect

    Damm, C. C.

    1983-08-18

    The history of the magnetic-mirror approach to a fusion reactor is primarily the history of our understanding and control of several crucial physics issues, coupled with progress in the technology of heating and confining a reacting plasma. The basic requirement of an MHD-stable plasma equilibrium was achieved following the early introduction of minimum-B multipolar magnetic fields. In refined form, the same magnetic-well principle carries over to our present experiments and to reactor designs. The higher frequency microinstabilities, arising from the non-Maxwellian particle distributions inherent in mirror machines, have gradually come under control as theoretical prescriptions for distribution functions have been applied in the experiments. Even with stability, the classical plasma leakage through the mirrors posed a serious question for reactor viability until the principle of electrostatic axial stoppering was applied in the tandem mirror configuration. Experiments to test this principle successfully demonstrated the substantial improvement in confinement predicted. Concurrent with advances in mirror plasma physics, development of both high-power neutral beam injectors and high-speed vacuum pumping techniques has played a crucial role in ongoing experiments. Together with superconducting magnets, cryogenic pumping, and high-power radiofrequency heating, these technologies have evolved to a level that extrapolates readily to meet the requirements of a tandem mirror fusion reactor.

  5. Machine Learning

    DTIC Science & Technology

    1990-04-01

    DTIC i.LE COPY RADC-TR-90-25 Final Technical Report April 1990 MACHINE LEARNING The MITRE Corporation Melissa P. Chase Cs) CTIC ’- CT E 71 IN 2 11990...S. FUNDING NUMBERS MACHINE LEARNING C - F19628-89-C-0001 PE - 62702F PR - MOlE S. AUTHO(S) TA - 79 Melissa P. Chase WUT - 80 S. PERFORMING...341.280.5500 pm I " Aw Sig rill Ia 2110-01 SECTION 1 INTRODUCTION 1.1 BACKGROUND Research in machine learning has taken two directions in the problem of

  6. Ultrastructure and immunocytochemical characteristics of cells in the octopus cell area of the rat cochlear nucleus: comparison with multipolar cells.

    PubMed

    Alibardi, Lorenzo

    2003-01-01

    Cells in the octopus cell area of the rat ventral cochlear nucleus have been connected to the monaural interpretation of spectral patterns of sound such as those derived from speech. This is possible by their fast onset of firing after each octopus cell and its dendrites have been contacted by many auditory fibres carrying different frequencies. The cytological characteristics that make these large cells able to perform such a function have been studied with ultrastructural immunocytochemistry for glycine, GABA and glutamate, and compared to that of other multipolar neurons of other regions of the ventral cochlear nucleus. Cells in the octopus cell area have an ultrastructure similar to large-giant D-multipolar neurons present in other areas of the cochlear nucleus, from which they differ by the presence of a larger excitatory axo-somatic synaptic input and larger mitochondria. Octopus cells are glycine and GABA negative, and glutamate positive with different degree. Large octopus cells receive more axo-somatic boutons than smaller octopus cells. Fusiform octopus cells are found sparsely within the intermediate acoustic striae. These cells are large to giant excitatory neurons (23-35 microm) with 62-85% of their irregular perimeter covered with large axo-somatic synaptic boutons. Most boutons contain round vesicles and are glycine and GABA negative but glutamate positive. The latter excitatory boutons represent about 70% of the input to octopus cells. Glycine positive boutons with flat and pleomorphic vesicles account for 9-10% of the input while GABA-ergic boutons with pleomorphic vesicles represent about 20% of the synaptic input. Other few, multipolar cells within the rat octopus cell area are surrounded by more inhibitory than excitatory terminals which contain flat and pleomorphic vesicles, a feature distinctive from that of true octopus cells. The latter resemble multipolar cells seen outside the octopus cell area that project to the contralateral inferior

  7. Induction linear accelerators

    NASA Astrophysics Data System (ADS)

    Birx, Daniel

    1992-03-01

    Among the family of particle accelerators, the Induction Linear Accelerator is the best suited for the acceleration of high current electron beams. Because the electromagnetic radiation used to accelerate the electron beam is not stored in the cavities but is supplied by transmission lines during the beam pulse it is possible to utilize very low Q (typically<10) structures and very large beam pipes. This combination increases the beam breakup limited maximum currents to of order kiloamperes. The micropulse lengths of these machines are measured in 10's of nanoseconds and duty factors as high as 10-4 have been achieved. Until recently the major problem with these machines has been associated with the pulse power drive. Beam currents of kiloamperes and accelerating potentials of megavolts require peak power drives of gigawatts since no energy is stored in the structure. The marriage of liner accelerator technology and nonlinear magnetic compressors has produced some unique capabilities. It now appears possible to produce electron beams with average currents measured in amperes, peak currents in kiloamperes and gradients exceeding 1 MeV/meter, with power efficiencies approaching 50%. The nonlinear magnetic compression technology has replaced the spark gap drivers used on earlier accelerators with state-of-the-art all-solid-state SCR commutated compression chains. The reliability of these machines is now approaching 1010 shot MTBF. In the following paper we will briefly review the historical development of induction linear accelerators and then discuss the design considerations.

  8. Monel Machining

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Castle Industries, Inc. is a small machine shop manufacturing replacement plumbing repair parts, such as faucet, tub and ballcock seats. Therese Castley, president of Castle decided to introduce Monel because it offered a chance to improve competitiveness and expand the product line. Before expanding, Castley sought NERAC assistance on Monel technology. NERAC (New England Research Application Center) provided an information package which proved very helpful. The NASA database was included in NERAC's search and yielded a wealth of information on machining Monel.

  9. Point-by-point pulmonary vein antrum isolation guided by intracardiac echocardiography and 3D mapping and duty-cycled multipolar AF ablation: effect of multipolar ablation on procedure duration and fluoroscopy time.

    PubMed

    Khaykin, Yaariv; Zarnett, Lauren; Friedlander, Daniel; Wulffhart, Zaev A; Whaley, Bonnie; Giewercer, David; Tsang, Bernice; Verma, Atul

    2012-09-01

    Pulmonary vein antrum isolation (PVAI) guided by intracardiac echocardiography and a roaming circular mapping catheter is an effective treatment modality for atrial fibrillation. Unfortunately, the complexity of this technique leads to long procedure times and high fluoroscopy exposure. Single-catheter multipolar ablation holds the promise to reduce these parameters. This study examined the effect of the conventional point-by-point PVAI with that of single-catheter multipolar ablation on the procedural characteristics and clinical outcomes of atrial fibrillation ablation. Referred patients underwent PVAI guided by a magnetic-based 3D mapping (CARTO 3(®) System; group 1) or duty-cycled multipolar AF ablation using the pulmonary vein ablation catheter (PVAC, group 2) between June 2010 and May 2011. Data were analyzed from 19 patients in group 1 and 31 patients in group 2. There was no significant difference in the length of the procedure between the two groups (135 ± 26 vs 125 ± 25 min, P = 0.20). Patients who underwent ablation using PVAC spent significantly less time in the procedure room pre- and post-procedure than those who underwent conventional PVAI (205 ± 38 vs 179 ± 30 min, P = 0.02) and had a significantly shorter fluoroscopy exposure (50 ± 16 vs 36 ± 14 min, P = 0.003) and radiofrequency energy delivery time (54 ± 26 vs 32 ± 33 min, P = 0.02). No differences in safety and efficacy were seen between the groups. Single-catheter multipolar AF ablation was associated with significantly lower fluoroscopy duration, radiofrequency energy delivery time, and the time the patient spent in the procedure room before and after ablation, although measured short-term clinical outcomes were similar.

  10. Gravitational induction

    NASA Astrophysics Data System (ADS)

    Bini, Donato; Cherubini, Christian; Chicone, Carmen; Mashhoon, Bahram

    2008-11-01

    We study the linear post-Newtonian approximation to general relativity known as gravitoelectromagnetism (GEM); in particular, we examine the similarities and differences between GEM and electrodynamics. Notwithstanding some significant differences between them, we find that a special nonstationary metric in GEM can be employed to show explicitly that it is possible to introduce gravitational induction within GEM in close analogy with Faraday's law of induction and Lenz's law in electrodynamics. Some of the physical implications of gravitational induction are briefly discussed.

  11. Reelin, Rap1 and N-cadherin orient the migration of multipolar neurons in the developing neocortex.

    PubMed

    Jossin, Yves; Cooper, Jonathan A

    2011-06-01

    Projection neurons migrate from the ventricular zone to the neocortical plate during the development of the mouse brain. Their overall movement is radial, but they become multipolar and move nonradially in the intermediate zone. Here we show that Reelin, the Rap1 GTPase and N-cadherin (NCad) are important for multipolar neurons to polarize their migration toward the cortical plate. Inhibition and rescue experiments indicated that Reelin regulates migration through Rap1 and Akt, and that the Rap1-regulated GTPases RalA, RalB, Rac1 and Cdc42 are also involved. We found that Rap1 regulated the plasma membrane localization of NCad and NCad rescued radial polarization when Rap1 was inhibited. However, inhibition of Rap1 or NCad had little effect on glia-dependent locomotion. We propose a multistep mechanism in which Reelin activates Rap1, Rap1 upregulates NCad, and NCad is needed to orient cell migration.

  12. Inductive reasoning.

    PubMed

    Hayes, Brett K; Heit, Evan; Swendsen, Haruka

    2010-03-01

    Inductive reasoning entails using existing knowledge or observations to make predictions about novel cases. We review recent findings in research on category-based induction as well as theoretical models of these results, including similarity-based models, connectionist networks, an account based on relevance theory, Bayesian models, and other mathematical models. A number of touchstone empirical phenomena that involve taxonomic similarity are described. We also examine phenomena involving more complex background knowledge about premises and conclusions of inductive arguments and the properties referenced. Earlier models are shown to give a good account of similarity-based phenomena but not knowledge-based phenomena. Recent models that aim to account for both similarity-based and knowledge-based phenomena are reviewed and evaluated. Among the most important new directions in induction research are a focus on induction with uncertain premise categories, the modeling of the relationship between inductive and deductive reasoning, and examination of the neural substrates of induction. A common theme in both the well-established and emerging lines of induction research is the need to develop well-articulated and empirically testable formal models of induction. Copyright © 2010 John Wiley & Sons, Ltd. For further resources related to this article, please visit the WIREs website.

  13. ADAM17 is critical for multipolar exit and radial migration of neuronal intermediate progenitor cells in mice cerebral cortex.

    PubMed

    Li, Qingyu; Zhang, Zhengyu; Li, Zengmin; Zhou, Mei; Liu, Bin; Pan, Le; Ma, Zhixing; Zheng, Yufang

    2013-01-01

    The radial migration of neuronal progenitor cells is critical for the development of cerebral cortex layers. They go through a critical step transforming from multipolar to bipolar before outward migration. A Disintegrin and Metalloprotease 17 (ADAM17) is a transmembrane protease which can process many substrates involved in cell-cell interaction, including Notch, ligands of EGFR, and some cell adhesion molecules. In this study, we used in utero electroporation to knock down or overexpress ADAM17 at embryonic day 14.5 (E14.5) in neuronal progenitor cells to examine the role of ADAM17 in cortical embryonic neurogenesis. Our results showed that the radial migration of ADAM17-knocked down cells were normal till E16.5 and reached the intermediate zone (IZ). Then most transfected cells stopped migration and stayed at the IZ to inner cortical plate (CP) layer at E18.5, and there was higher percentage of multipolar cells at IZ layer in the ADAM17-knocked down group compared to the cells in control group. Marker staining revealed that those ADAM17-knocked down cells differentiated normally from neural stem cells (NSCs) to neuronal intermediate progenitor cells (nIPCs) but did not differentiate into mature neurons. The migration and multipolar exit defects caused by ADAM17 knockdown could be partially rescued by over-expressing an shRNA resistant ADAM17, while overexpressing ADAM17 alone did not affect the radial migration. Taken together, our results showed for the first time that, ADAM17 is critical in regulating the multipolar-stage exit and radial migration of the nIPCs during telencephalon cortex development in mice.

  14. Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate.

    PubMed

    Miyoshi, Goichi; Fishell, Gord

    2012-06-21

    Pyramidal cells of the cerebral cortex are born in the ventricular zone and migrate through the intermediate zone to enter into the cortical plate. In the intermediate zone, these migrating precursors move tangentially and initiate the extension of their axons by transiently adopting a characteristic multipolar morphology. We observe that expression of the forkhead transcription factor FoxG1 is dynamically regulated during this transitional period. By utilizing conditional genetic strategies, we show that the downregulation of FoxG1 at the beginning of the multipolar cell phase induces Unc5D expression, the timing of which ultimately determines the laminar identity of pyramidal neurons. In addition, we demonstrate that the re-expression of FoxG1 is required for cells to transit out of the multipolar cell phase and to enter into the cortical plate. Thus, the dynamic expression of FoxG1 during migration within the intermediate zone is essential for the proper assembly of the cerebral cortex.

  15. Huntingtin-Mediated Multipolar-Bipolar Transition of Newborn Cortical Neurons Is Critical for Their Postnatal Neuronal Morphology.

    PubMed

    Barnat, Monia; Le Friec, Julien; Benstaali, Caroline; Humbert, Sandrine

    2017-01-04

    In the developing cortex, projection neurons undergo multipolar-bipolar transition, radial-directed migration, and maturation. The contribution of these developmental steps to the structure of the adult cortex is not completely understood. Here, we report that huntingtin (HTT), the protein mutated in Huntington's disease, is enriched in polarizing projection neurons. The depletion of HTT in postmitotic projection neurons leads to the mislocalization of layer-specific neuronal populations in the mouse neocortex. HTT is required for the multipolar-bipolar transition of projection neurons and for the maintenance of their bipolar shape during their radial migration. HTT mediates these effects in vivo through the regulation of RAB11-dependent N-Cadherin trafficking. Importantly, HD pathological HTT alters RAB11-dependent neuronal migration. Finally, we show that the cortical defects resulting from the postmitotic loss of HTT specifically during embryonic development affect neuronal morphology at adulthood. Our data reveal a new HTT-RAB11-N-Cadherin pathway regulating multipolar-bipolar transition with direct implications for mature brain. VIDEO ABSTRACT.

  16. Multipolarity of the 2-→1- , ground-state transition in 210Bi via multivariable angular correlation analysis

    NASA Astrophysics Data System (ADS)

    Cieplicka-Oryńczak, N.; Szpak, B.; Leoni, S.; Fornal, B.; Bazzacco, D.; Blanc, A.; Bocchi, G.; Bottoni, S.; de France, G.; Jentschel, M.; Köster, U.; Mutti, P.; Simpson, G.; Soldner, T.; Ur, C.; Urban, W.

    2016-07-01

    The multipolarity of the main transition leading to the ground state in 210Bi was investigated using the angular correlations of γ rays. The analyzed γ -coincidence data were obtained from the 209Bi(n ,γ )210Bi experiment performed at Institut Laue-Langevin Grenoble at the PF1B cold-neutron facility. The EXILL (EXOGAM at the ILL) multidetector array, consisting of 16 high-purity germanium detectors, was used to detect γ transitions. The mixing ratio of the 320-keV γ ray was defined by minimizing a multivariable χΣ2 function constructed from the coefficients of angular correlation functions for seven pairs of strong transitions in 210Bi. As a result, the almost pure M 1 multipolarity of the 320-keV γ ray was obtained, with an E 2 admixture of less than 0.6% only (95% confidence limit). Based on this multipolarity the neutron-capture cross section leading to the ground state in 210Bi, that decays in turn to radiotoxic 210Po, was determined to be within the limits 21.3(9) and 21.5(9) mb. This result is important for nuclear reactor applications.

  17. Tuberculoventral neurons project to the multipolar cell area but not to the octopus cell area of the posteroventral cochlear nucleus.

    PubMed

    Wickesberg, R E; Whitlon, D; Oertel, D

    1991-11-15

    Tuberculoventral neurons in the deep layer of the dorsal cochlear nucleus (DCN) provide frequency-specific inhibition to neurons in the anteroventral cochlear nucleus (AVCN) of the mouse (Wickesberg and Oertel, '88, '90). The present experiments examine the projection from the deep DCN to the posteroventral cochlear nucleus (PVCN). Horseradish peroxidase (HRP) injections into the PVCN reveal that the multipolar cell area, but not the octopus cell area, is innervated by neurons in the deep layer of the DCN. Injections into the multipolar cell area, in the rostral and ventral PVCN, labeled neurons across the entire rostrocaudal extent of the deep DCN. The labeled tuberculoventral neurons generally lay within the band of labeled auditory nerve terminals in the DCN. Injections of HRP into the octopus cell area, in the dorsal caudal PVCN, labeled almost no cells within the band of auditory nerve fiber terminals that were labeled by the same injection. The inhibition from tuberculoventral neurons onto ventral cochlear nucleus (VCN) neurons is likely to be mediated by glycine (Wickesberg and Oertel, '90). Slices of the cochlear nuclear complex were immunolabeled by an antibody against glycine conjugated with glutaraldehyde to bovine serum albumin (Wenthold et al., '87). Glycine-like immunoreactivity was found throughout the DCN, the AVCN and the multipolar cell area, but there was little labeling in the octopus cell area. This finding provides independent evidence that tuberculoventral neurons do not innervate the octopus cell area and indicates that the octopus cell area is anatomically and functionally distinct.

  18. Induction technology optimization code

    SciTech Connect

    Caporaso, G.J.; Brooks, A.L.; Kirbie, H.C.

    1992-08-21

    A code has been developed to evaluate relative costs of induction accelerator driver systems for relativistic klystrons. The code incorporates beam generation, transport and pulsed power system constraints to provide an integrated design tool. The code generates an injector/accelerator combination which satisfies the top level requirements and all system constraints once a small number of design choices have been specified (rise time of the injector voltage and aspect ratio of the ferrite induction cores, for example). The code calculates dimensions of accelerator mechanical assemblies and values of all electrical components. Cost factors for machined parts, raw materials and components are applied to yield a total system cost. These costs are then plotted as a function of the two design choices to enable selection of an optimum design based on various criteria. The Induction Technology Optimization Study (ITOS) was undertaken to examine viable combinations of a linear induction accelerator and a relativistic klystron (RK) for high power microwave production. It is proposed, that microwaves from the RK will power a high-gradient accelerator structure for linear collider development. Previous work indicates that the RK will require a nominal 3-MeV, 3-kA electron beam with a 100-ns flat top. The proposed accelerator-RK combination will be a high average power system capable of sustained microwave output at a 300-Hz pulse repetition frequency. The ITOS code models many combinations of injector, accelerator, and pulse power designs that will supply an RK with the beam parameters described above.

  19. Multipolar mitosis and aneuploidy after chrysotile treatment: a consequence of abscission failure and cytokinesis regression.

    PubMed

    Cortez, Beatriz Araujo; Rezende-Teixeira, Paula; Redick, Sambra; Doxsey, Stephen; Machado-Santelli, Glaucia Maria

    2016-02-23

    Chrysotile, like other types of asbestos, has been associated with mesothelioma, lung cancer and asbestosis. However, the cellular abnormalities induced by these fibers involved in cancer development have not been elucidated yet. Previous works show that chrysotile fibers induce features of cancer cells, such as aneuploidy, multinucleation and multipolar mitosis. In the present study, normal and cancer derived human cell lines were treated with chrysotile and the cellular and molecular mechanisms related to generation of aneuploid cells was elucidated. The first alteration observed was cytokinesis regression, the main cause of multinucleated cells formation and centrosome amplification. The multinucleated cells formed after cytokinesis regression were able to progress through cell cycle and generated aneuploid cells after abnormal mitosis. To understand the process of cytokinesis regression, localization of cytokinetic proteins was investigated. It was observed mislocalization of Anillin, Aurora B, Septin 9 and Alix in the intercellular bridge, and no determination of secondary constriction and abscission sites. Fiber treatment also led to overexpression of genes related to cancer, cytokinesis and cell cycle. The results show that chrysotile fibers induce cellular and molecular alterations in normal and tumor cells that have been related to cancer initiation and progression, and that tetraploidization and aneuploid cell formation are striking events after fiber internalization, which could generate a favorable context to cancer development.

  20. Cholesterol oxidase: ultrahigh-resolution crystal structure and multipolar atom model-based analysis.

    PubMed

    Zarychta, Bartosz; Lyubimov, Artem; Ahmed, Maqsood; Munshi, Parthapratim; Guillot, Benoît; Vrielink, Alice; Jelsch, Christian

    2015-04-01

    Examination of protein structure at the subatomic level is required to improve the understanding of enzymatic function. For this purpose, X-ray diffraction data have been collected at 100 K from cholesterol oxidase crystals using synchrotron radiation to an optical resolution of 0.94 Å. After refinement using the spherical atom model, nonmodelled bonding peaks were detected in the Fourier residual electron density on some of the individual bonds. Well defined bond density was observed in the peptide plane after averaging maps on the residues with the lowest thermal motion. The multipolar electron density of the protein-cofactor complex was modelled by transfer of the ELMAM2 charge-density database, and the topology of the intermolecular interactions between the protein and the flavin adenine dinucleotide (FAD) cofactor was subsequently investigated. Taking advantage of the high resolution of the structure, the stereochemistry of main-chain bond lengths and of C=O···H-N hydrogen bonds was analyzed with respect to the different secondary-structure elements.

  1. The Shaping of the Multipolar Pre-planetary Nebula CRL 618 by Multidirectional Bullets

    NASA Astrophysics Data System (ADS)

    Huang, Po-Sheng; Lee, Chin-Fei; Moraghan, Anthony; Smith, Michael

    2016-04-01

    In order to understand the formation of the multipolar structures of the pre-planetary nebula CRL 618, we perform 3D simulations using a multidirectional bullet model. The optical lobes of CRL 618 and fast molecular outflows at the tips of the lobes have been found to have similar expansion ages of ˜100 yr. Additional fast molecular outflows were found near the source along the outflow axes with ages of ˜45 yr, suggesting a second episode of bullet ejections. Thus, in our simulations, two episodes of bullet ejections are assumed. The shaping process is simulated using the ZEUS-3D hydrodynamics code that includes molecular and atomic cooling. In addition, molecular chemistry is also included to calculate the CO intensity maps. Our results show the following: (1) Multiepoch bullets interacting with the toroidal dense core can produce the collimated multiple lobes as seen in CRL 618. The total mass of the bullets is ˜0.034 M⊙, consistent with the observed high-velocity (HV) CO emission in fast molecular outflows. (2) The simulated CO J = 3-2 intensity maps show that the low-velocity cavity wall and the HV outflows along the lobes are reasonably consistent with the observations. The position-velocity diagram of the outflows along the outflow axes shows a linear increase of velocity with distance, similar to the observations. The ejections of these bullets could be due to magnetorotational explosions or nova-like explosions around a binary companion.

  2. The Slope Imaging Multi-Polarization Photon-Counting Lidar: Development and Performance Results

    NASA Technical Reports Server (NTRS)

    Dabney, Phillip

    2010-01-01

    The Slope Imaging Multi-polarization Photon-counting Lidar is an airborne instrument developed to demonstrate laser altimetry measurement methods that will enable more efficient observations of topography and surface properties from space. The instrument was developed through the NASA Earth Science Technology Office Instrument Incubator Program with a focus on cryosphere remote sensing. The SIMPL transmitter is an 11 KHz, 1064 nm, plane-polarized micropulse laser transmitter that is frequency doubled to 532 nm and split into four push-broom beams. The receiver employs single-photon, polarimetric ranging at 532 and 1064 nm using Single Photon Counting Modules in order to achieve simultaneous sampling of surface elevation, slope, roughness and depolarizing scattering properties, the latter used to differentiate surface types. Data acquired over ice-covered Lake Erie in February, 2009 are documenting SIMPL s measurement performance and capabilities, demonstrating differentiation of open water and several ice cover types. ICESat-2 will employ several of the technologies advanced by SIMPL, including micropulse, single photon ranging in a multi-beam, push-broom configuration operating at 532 nm.

  3. Multipolar phase in frustrated spin-1/2 and spin-1 chains

    NASA Astrophysics Data System (ADS)

    Parvej, Aslam; Kumar, Manoranjan

    2017-08-01

    The J1-J2 spin-chain model with nearest-neighbor J1 and next-nearest-neighbor antiferromagnetic J2 interaction is one of the most popular frustrated magnetic models. This model system has been extensively studied theoretically and applied to explain the magnetic properties of the real low-dimensional materials. However, the existence of different phases for the J1-J2 model in an axial magnetic field h is either not understood or has been controversial. In this paper, we show the existence of higher order p >4 multipolar phase near the critical point (J2/J1)c=-0.25 . The criterion to detect the quadrupolar or spin nematic (SN)/spin density wave of type two (SDW2) phase using the inelastic neutron scattering (INS) experiment data is also discussed, and INS data of LiCuVO4 compound is modeled. We discuss the dimerized and degenerate ground state in the quadrupolar phase. The major contribution of binding energy in the spin-1/2 system comes from the longitudinal component of the nearest-neighbor bonds. We also study spin nematic /SDW2 phase in spin-1 system in large J2/J1 limit.

  4. Multipolar mitosis and aneuploidy after chrysotile treatment: a consequence of abscission failure and cytokinesis regression

    PubMed Central

    Cortez, Beatriz Araujo; Teixeira, Paula Rezende; Redick, Sambra; Doxsey, Stephen; Machado-Santelli, Glaucia Maria

    2016-01-01

    Chrysotile, like other types of asbestos, has been associated with mesothelioma, lung cancer and asbestosis. However, the cellular abnormalities induced by these fibers involved in cancer development have not been elucidated yet. Previous works show that chrysotile fibers induce features of cancer cells, such as aneuploidy, multinucleation and multipolar mitosis. In the present study, normal and cancer derived human cell lines were treated with chrysotile and the cellular and molecular mechanisms related to generation of aneuploid cells was elucidated. The first alteration observed was cytokinesis regression, the main cause of multinucleated cells formation and centrosome amplification. The multinucleated cells formed after cytokinesis regression were able to progress through cell cycle and generated aneuploid cells after abnormal mitosis. To understand the process of cytokinesis regression, localization of cytokinetic proteins was investigated. It was observed mislocalization of Anillin, Aurora B, Septin 9 and Alix in the intercellular bridge, and no determination of secondary constriction and abscission sites. Fiber treatment also led to overexpression of genes related to cancer, cytokinesis and cell cycle. The results show that chrysotile fibers induce cellular and molecular alterations in normal and tumor cells that have been related to cancer initiation and progression, and that tetraploidization and aneuploid cell formation are striking events after fiber internalization, which could generate a favorable context to cancer development. PMID:26788989

  5. The Slope Imaging Multi-Polarization Photon-Counting Lidar: Development and Performance Results

    NASA Technical Reports Server (NTRS)

    Dabney, Phillip

    2010-01-01

    The Slope Imaging Multi-polarization Photon-counting Lidar is an airborne instrument developed to demonstrate laser altimetry measurement methods that will enable more efficient observations of topography and surface properties from space. The instrument was developed through the NASA Earth Science Technology Office Instrument Incubator Program with a focus on cryosphere remote sensing. The SIMPL transmitter is an 11 KHz, 1064 nm, plane-polarized micropulse laser transmitter that is frequency doubled to 532 nm and split into four push-broom beams. The receiver employs single-photon, polarimetric ranging at 532 and 1064 nm using Single Photon Counting Modules in order to achieve simultaneous sampling of surface elevation, slope, roughness and depolarizing scattering properties, the latter used to differentiate surface types. Data acquired over ice-covered Lake Erie in February, 2009 are documenting SIMPL s measurement performance and capabilities, demonstrating differentiation of open water and several ice cover types. ICESat-2 will employ several of the technologies advanced by SIMPL, including micropulse, single photon ranging in a multi-beam, push-broom configuration operating at 532 nm.

  6. Role of the multipolar electrostatic interaction energy components in strong and weak cation-π interactions.

    PubMed

    Kadlubanski, Pawel; Calderón-Mojica, Katherine; Rodriguez, Weyshla A; Majumdar, D; Roszak, Szczepan; Leszczynski, Jerzy

    2013-08-22

    Density functional and Møller-Plesset second-order perturbation (MP2) calculations have been carried out on various model cation-π complexes formed through the interactions of Mg(2+), Ca(2+), and NH4(+) cations with benzene, p-methylphenol, and 3-methylindole. Partial hydration of the metal cations was also considered in these model studies to monitor the effect of hydration of cations in cation-π interactions. The binding energies of these complexes were computed from the fully optimized structures using coupled cluster calculations including triple excitations (CCSD(T)) and Gaussian-G4-MP2 (G4MP2) techniques. An analysis of the charge sharing between the donor (the π-systems) and the acceptors (the cations) together with the partitioning of total interaction energies revealed that the strong and weak cation-π interactions have similar electrostatic interaction properties. Further decomposition of such electrostatic terms into their multipolar components showed the importance of the charge-dipole, charge-quadrupole, and charge-octopole terms in shaping the electrostatic forces in such interactions. The computed vibrational spectra of the complexes were analyzed for the specific cation-π interaction modes and have been shown to contain the signature of higher order electrostatic interaction energy components (quadrupole and octopole) in such interactions.

  7. Spatially resolved simulations of membrane reactions and dynamics: Multipolar reaction DPD

    NASA Astrophysics Data System (ADS)

    Füchslin, R. M.; Maeke, T.; McCaskill, J. S.

    2009-08-01

    Biophysical chemistry of mesoscale systems and quantitative modeling in systems biology now require a simulation methodology unifying chemical reaction kinetics with essential collective physics. This will enable the study of the collective dynamics of complex chemical and structural systems in a spatially resolved manner with a combinatorially complex variety of different system constituents. In order to allow a direct link-up with experimental data (e.g. high-throughput fluorescence images) the simulations must be constructed locally, i.e. mesoscale phenomena have to emerge from local composition and interactions that can be extracted from experimental data. Under suitable conditions, the simulation of such local interactions must lead to processes such as vesicle budding, transport of membrane-bounded compartments and protein sorting, all of which result from a sophisticated interplay between chemical and mechanical processes and require the link-up of different length scales. In this work, we show that introducing multipolar interactions between particles in dissipative particle dynamics (DPD) leads to extended membrane structures emerging in a self-organized manner and exhibiting the necessary mechanical stability for transport, correct scaling behavior, and membrane fluidity so as to provide a two-dimensional self-organizing dynamic reaction environment for kinetic studies in the context of cell biology. Supplementary material in the form of video files available from the Journal web page at 10.1140/epje/i2009-10482-x and are accessible for authorised users. in here

  8. Two-site fluctuations and multipolar intersite exchange interactions in strongly correlated systems

    NASA Astrophysics Data System (ADS)

    Pourovskii, L. V.

    2016-09-01

    An approach is proposed for evaluating dipolar and multipolar intersite interactions in strongly correlated materials. This approach is based on the single-site dynamical mean-field theory (DMFT) in conjunction with the atomic approximation for the local self-energy. Starting from the local-moment paramagnetic state described by DMFT, we derive intersite interactions by considering the response of the DMFT grand potential to small fluctuations of atomic configurations on two neighboring sites. The present method is validated by applying it to one-band and two-band eg Hubbard models on the simple-cubic 3 d lattice. It is also applied to study the spin-orbital order in the parent cubic structure of ternary chromium fluoride KCrF3. We obtain the onset of a G-type antiferro-orbital order at a significantly lower temperature compared to that in real distorted KCrF3. In contrast, its layered A-type antiferromagnetic order and Néel temperature are rather well reproduced. The calculated full Kugel-Khomskii Hamiltonian contains spin-orbital coupling terms inducing a misalignment in the antiferro-orbital order upon the onset of antiferromagnetism.

  9. THE SHAPING OF THE MULTIPOLAR PRE-PLANETARY NEBULA CRL 618 BY MULTIDIRECTIONAL BULLETS

    SciTech Connect

    Huang, Po-Sheng; Lee, Chin-Fei; Moraghan, Anthony; Smith, Michael

    2016-04-01

    In order to understand the formation of the multipolar structures of the pre-planetary nebula CRL 618, we perform 3D simulations using a multidirectional bullet model. The optical lobes of CRL 618 and fast molecular outflows at the tips of the lobes have been found to have similar expansion ages of ∼100 yr. Additional fast molecular outflows were found near the source along the outflow axes with ages of ∼45 yr, suggesting a second episode of bullet ejections. Thus, in our simulations, two episodes of bullet ejections are assumed. The shaping process is simulated using the ZEUS-3D hydrodynamics code that includes molecular and atomic cooling. In addition, molecular chemistry is also included to calculate the CO intensity maps. Our results show the following: (1) Multiepoch bullets interacting with the toroidal dense core can produce the collimated multiple lobes as seen in CRL 618. The total mass of the bullets is ∼0.034 M{sub ⊙}, consistent with the observed high-velocity (HV) CO emission in fast molecular outflows. (2) The simulated CO J = 3–2 intensity maps show that the low-velocity cavity wall and the HV outflows along the lobes are reasonably consistent with the observations. The position–velocity diagram of the outflows along the outflow axes shows a linear increase of velocity with distance, similar to the observations. The ejections of these bullets could be due to magnetorotational explosions or nova-like explosions around a binary companion.

  10. Workout Machine

    NASA Technical Reports Server (NTRS)

    1995-01-01

    The Orbotron is a tri-axle exercise machine patterned after a NASA training simulator for astronaut orientation in the microgravity of space. It has three orbiting rings corresponding to roll, pitch and yaw. The user is in the middle of the inner ring with the stomach remaining in the center of all axes, eliminating dizziness. Human power starts the rings spinning, unlike the NASA air-powered system. Marketed by Fantasy Factory (formerly Orbotron, Inc.), the machine can improve aerobic capacity, strength and endurance in five to seven minute workouts.

  11. CT-guided Bipolar and Multipolar Radiofrequency Ablation (RF Ablation) of Renal Cell Carcinoma: Specific Technical Aspects and Clinical Results

    SciTech Connect

    Sommer, C. M.; Lemm, G.; Hohenstein, E.; Bellemann, N.; Stampfl, U.; Goezen, A. S.; Rassweiler, J.; Kauczor, H. U.; Radeleff, B. A.; Pereira, P. L.

    2013-06-15

    Purpose. This study was designed to evaluate the clinical efficacy of CT-guided bipolar and multipolar radiofrequency ablation (RF ablation) of renal cell carcinoma (RCC) and to analyze specific technical aspects between both technologies. Methods. We included 22 consecutive patients (3 women; age 74.2 {+-} 8.6 years) after 28 CT-guided bipolar or multipolar RF ablations of 28 RCCs (diameter 2.5 {+-} 0.8 cm). Procedures were performed with a commercially available RF system (Celon AG Olympus, Berlin, Germany). Technical aspects of RF ablation procedures (ablation mode [bipolar or multipolar], number of applicators and ablation cycles, overall ablation time and deployed energy, and technical success rate) were analyzed. Clinical results (local recurrence-free survival and local tumor control rate, renal function [glomerular filtration rate (GFR)]) and complication rates were evaluated. Results. Bipolar RF ablation was performed in 12 procedures and multipolar RF ablation in 16 procedures (2 applicators in 14 procedures and 3 applicators in 2 procedures). One ablation cycle was performed in 15 procedures and two ablation cycles in 13 procedures. Overall ablation time and deployed energy were 35.0 {+-} 13.6 min and 43.7 {+-} 17.9 kJ. Technical success rate was 100 %. Major and minor complication rates were 4 and 14 %. At an imaging follow-up of 15.2 {+-} 8.8 months, local recurrence-free survival was 14.4 {+-} 8.8 months and local tumor control rate was 93 %. GFR did not deteriorate after RF ablation (50.8 {+-} 16.6 ml/min/1.73 m{sup 2} before RF ablation vs. 47.2 {+-} 11.9 ml/min/1.73 m{sup 2} after RF ablation; not significant). Conclusions. CT-guided bipolar and multipolar RF ablation of RCC has a high rate of clinical success and low complication rates. At short-term follow-up, clinical efficacy is high without deterioration of the renal function.

  12. Machine rates for selected forest harvesting machines

    Treesearch

    R.W. Brinker; J. Kinard; Robert Rummer; B. Lanford

    2002-01-01

    Very little new literature has been published on the subject of machine rates and machine cost analysis since 1989 when the Alabama Agricultural Experiment Station Circular 296, Machine Rates for Selected Forest Harvesting Machines, was originally published. Many machines discussed in the original publication have undergone substantial changes in various aspects, not...

  13. Wacky Machines

    ERIC Educational Resources Information Center

    Fendrich, Jean

    2002-01-01

    Collectors everywhere know that local antique shops and flea markets are treasure troves just waiting to be plundered. Science teachers might take a hint from these hobbyists, for the next community yard sale might be a repository of old, quirky items that are just the things to get students thinking about simple machines. By introducing some…

  14. Wacky Machines

    ERIC Educational Resources Information Center

    Fendrich, Jean

    2002-01-01

    Collectors everywhere know that local antique shops and flea markets are treasure troves just waiting to be plundered. Science teachers might take a hint from these hobbyists, for the next community yard sale might be a repository of old, quirky items that are just the things to get students thinking about simple machines. By introducing some…

  15. Induction voidmeter

    DOEpatents

    Anderson, T.T.; Roop, C.J.; Schmidt, K.J.; Brewer, J.

    1983-12-21

    An induction voidmeter for detecting voids in a conductive fluid may comprise: a four arm bridge circuit having two adjustable circuit elements connected as opposite arms of said bridge, an input branch, and an output branch; two induction coils, bifilarly wound together, connected as the remaining two opposing arms of said bridge circuit and positioned such that the conductive fluid passes through said coils; means for applying an AC excitation signal to said input branch; and means for detecting the output signal generated in response to said excitation signal across said output branch. The induction coils may be located outside or inside a non-magnetic pipe containing the conductive fluid.

  16. Induction voidmeter

    DOEpatents

    Anderson, Thomas T.; Roop, Conard J.; Schmidt, Kenneth J.; Brewer, John

    1986-01-01

    An induction voidmeter for detecting voids in a conductive fluid may comprise: a four arm bridge circuit having two adjustable circuit elements connected as opposite arms of said bridge circuit, an input branch, and an output branch; two induction coils, bifilarly wound together, connected as the remaining two opposing arms of said bridge circuit and positioned such that the conductive fluid passes through said coils; applying an AC excitation signal to said input branch; and detecting the output signal generated in response to said excitation signal across said output branch. The induction coils may be located outside or inside a non-magnetic pipe containing the conductive fluid.

  17. A Double-Sided Linear Primary Permanent Magnet Vernier Machine

    PubMed Central

    2015-01-01

    The purpose of this paper is to present a new double-sided linear primary permanent magnet (PM) vernier (DSLPPMV) machine, which can offer high thrust force, low detent force, and improved power factor. Both PMs and windings of the proposed machine are on the short translator, while the long stator is designed as a double-sided simple iron core with salient teeth so that it is very robust to transmit high thrust force. The key of this new machine is the introduction of double stator and the elimination of translator yoke, so that the inductance and the volume of the machine can be reduced. Hence, the proposed machine offers improved power factor and thrust force density. The electromagnetic performances of the proposed machine are analyzed including flux, no-load EMF, thrust force density, and inductance. Based on using the finite element analysis, the characteristics and performances of the proposed machine are assessed. PMID:25874250

  18. A double-sided linear primary permanent magnet vernier machine.

    PubMed

    Du, Yi; Zou, Chunhua; Liu, Xianxing

    2015-01-01

    The purpose of this paper is to present a new double-sided linear primary permanent magnet (PM) vernier (DSLPPMV) machine, which can offer high thrust force, low detent force, and improved power factor. Both PMs and windings of the proposed machine are on the short translator, while the long stator is designed as a double-sided simple iron core with salient teeth so that it is very robust to transmit high thrust force. The key of this new machine is the introduction of double stator and the elimination of translator yoke, so that the inductance and the volume of the machine can be reduced. Hence, the proposed machine offers improved power factor and thrust force density. The electromagnetic performances of the proposed machine are analyzed including flux, no-load EMF, thrust force density, and inductance. Based on using the finite element analysis, the characteristics and performances of the proposed machine are assessed.

  19. Drilling Machines: Vocational Machine Shop.

    ERIC Educational Resources Information Center

    Thomas, John C.

    The lessons and supportive information in this field tested instructional block provide a guide for teachers in developing a machine shop course of study in drilling. The document is comprised of operation sheets, information sheets, and transparency masters for 23 lessons. Each lesson plan includes a performance objective, material and tools,…

  20. Equivalence Between Squirrel Cage and Sheet Rotor Induction Motor

    NASA Astrophysics Data System (ADS)

    Dwivedi, Ankita; Singh, S. K.; Srivastava, R. K.

    2016-06-01

    Due to topological changes in dual stator induction motor and high cost of its fabrication, it is convenient to replace the squirrel cage rotor with a composite sheet rotor. For an experimental machine, the inner and outer stator stampings are normally available whereas the procurement of rotor stampings is quite cumbersome and is not always cost effective. In this paper, the equivalence between sheet/solid rotor induction motor and squirrel cage induction motor has been investigated using layer theory of electrical machines, so as to enable one to utilize sheet/solid rotor in dual port experimental machines.

  1. Multipolar Ewald Methods, 2: Applications Using a Quantum Mechanical Force Field

    PubMed Central

    2015-01-01

    A fully quantum mechanical force field (QMFF) based on a modified “divide-and-conquer” (mDC) framework is applied to a series of molecular simulation applications, using a generalized Particle Mesh Ewald method extended to multipolar charge densities. Simulation results are presented for three example applications: liquid water, p-nitrophenylphosphate reactivity in solution, and crystalline N,N-dimethylglycine. Simulations of liquid water using a parametrized mDC model are compared to TIP3P and TIP4P/Ew water models and experiment. The mDC model is shown to be superior for cluster binding energies and generally comparable for bulk properties. Examination of the dissociative pathway for dephosphorylation of p-nitrophenylphosphate shows that the mDC method evaluated with the DFTB3/3OB and DFTB3/OPhyd semiempirical models bracket the experimental barrier, whereas DFTB2 and AM1/d-PhoT QM/MM simulations exhibit deficiencies in the barriers, the latter for which is related, in part, to the anomalous underestimation of the p-nitrophenylate leaving group pKa. Simulations of crystalline N,N-dimethylglycine are performed and the overall structure and atomic fluctuations are compared with the experiment and the general AMBER force field (GAFF). The QMFF, which was not parametrized for this application, was shown to be in better agreement with crystallographic data than GAFF. Our simulations highlight some of the application areas that may benefit from using new QMFFs, and they demonstrate progress toward the development of accurate QMFFs using the recently developed mDC framework. PMID:25691830

  2. Multipolar Ewald methods, 2: applications using a quantum mechanical force field.

    PubMed

    Giese, Timothy J; Panteva, Maria T; Chen, Haoyuan; York, Darrin M

    2015-02-10

    A fully quantum mechanical force field (QMFF) based on a modified “divide-and-conquer” (mDC) framework is applied to a series of molecular simulation applications, using a generalized Particle Mesh Ewald method extended to multipolar charge densities. Simulation results are presented for three example applications: liquid water, p-nitrophenylphosphate reactivity in solution, and crystalline N,N-dimethylglycine. Simulations of liquid water using a parametrized mDC model are compared to TIP3P and TIP4P/Ew water models and experiment. The mDC model is shown to be superior for cluster binding energies and generally comparable for bulk properties. Examination of the dissociative pathway for dephosphorylation of p-nitrophenylphosphate shows that the mDC method evaluated with the DFTB3/3OB and DFTB3/OPhyd semiempirical models bracket the experimental barrier, whereas DFTB2 and AM1/d-PhoT QM/MM simulations exhibit deficiencies in the barriers, the latter for which is related, in part, to the anomalous underestimation of the p-nitrophenylate leaving group pKa. Simulations of crystalline N,N-dimethylglycine are performed and the overall structure and atomic fluctuations are compared with the experiment and the general AMBER force field (GAFF). The QMFF, which was not parametrized for this application, was shown to be in better agreement with crystallographic data than GAFF. Our simulations highlight some of the application areas that may benefit from using new QMFFs, and they demonstrate progress toward the development of accurate QMFFs using the recently developed mDC framework.

  3. Magnetar giant flares in multipolar magnetic fields. II. Flux rope eruptions with current sheets

    SciTech Connect

    Huang, Lei; Yu, Cong E-mail: cyu@ynao.ac.cn

    2014-11-20

    We propose a physical mechanism to explain giant flares and radio afterglows in terms of a magnetospheric model containing both a helically twisted flux rope and a current sheet (CS). With the appearance of a CS, we solve a mixed boundary value problem to get the magnetospheric field based on a domain decomposition method. We investigate properties of the equilibrium curve of the flux rope when the CS is present in background multipolar fields. In response to the variations at the magnetar surface, it quasi-statically evolves in stable equilibrium states. The loss of equilibrium occurs at a critical point and, beyond that point, it erupts catastrophically. New features show up when the CS is considered. In particular, we find two kinds of physical behaviors, i.e., catastrophic state transition and catastrophic escape. Magnetic energy would be released during state transitions. This released magnetic energy is sufficient to drive giant flares, and the flux rope would, therefore, go away from the magnetar quasi-statically, which is inconsistent with the radio afterglow. Fortunately, in the latter case, i.e., the catastrophic escape, the flux rope could escape the magnetar and go to infinity in a dynamical way. This is more consistent with radio afterglow observations of giant flares. We find that the minor radius of the flux rope has important implications for its eruption. Flux ropes with larger minor radii are more prone to erupt. We stress that the CS provides an ideal place for magnetic reconnection, which would further enhance the energy release during eruptions.

  4. Evaluation of focused multipolar stimulation for cochlear implants in long-term deafened cats

    NASA Astrophysics Data System (ADS)

    George, Shefin S.; Wise, Andrew K.; Fallon, James B.; Shepherd, Robert K.

    2015-06-01

    Objective. Focused multipolar (FMP) stimulation has been shown to produce restricted neural activation using intracochlear stimulation in animals with a normal population of spiral ganglion neurons (SGNs). However, in a clinical setting, the widespread loss of SGNs and peripheral fibres following deafness is expected to influence the effectiveness of FMP. Approach. We compared the efficacy of FMP stimulation to both monopolar (MP) and tripolar (TP) stimulation in long-term deafened cat cochleae (n = 8). Unlike our previous study, these cochleae contained <10% of the normal SGN population adjacent to the electrode array. We also evaluated the effect of electrode position on stimulation modes by using either modiolar facing or lateral wall facing half-band electrodes. The spread of neural activity across the inferior colliculus, a major nucleus within the central auditory pathway, was used as a measure of spatial selectivity. Main results. In cochleae with significant SGN degeneration, we observed that FMP and TP stimulation resulted in greater spatial selectivity than MP stimulation (p < 0.001). However, thresholds were significantly higher for FMP and TP stimulation compared to MP stimulation (p < 0.001). No difference between FMP and TP stimulation was found in any measures. The high threshold levels for FMP stimulation was significantly reduced without compromising spatial selectivity by varying the degree of current focusing (referred as ‘partial-FMP’ stimulation). Spatial selectivity of all stimulation modes was unaffected by the electrode position. Finally, spatial selectivity in long-term deafened cochleae was significantly less than that of cochleae with normal SGN population (George S S et al 2014 J. Neural Eng. 11 065003). Significance. The present results indicate that the greater spatial selectivity of FMP and TP stimulation over MP stimulation is maintained in cochleae with significant neural degeneration and is not adversely affected by electrode

  5. Post-fall-back evolution of multipolar magnetic fields and radio pulsar activation

    NASA Astrophysics Data System (ADS)

    Igoshev, A. P.; Elfritz, J. G.; Popov, S. B.

    2016-11-01

    It has long been unclear if the small-scale magnetic structures on the neutron star (NS) surface could survive the fall-back episode. The study of the Hall cascade by Cumming, Arras & Zweibel hinted that energy in small-scales structures should dissipate on short time-scales. Our new 2D magneto-thermal simulations suggest the opposite. For the first ˜10 kyr after the fall-back episode with accreted mass 10-3 M⊙, the observed NS magnetic field appears dipolar, which is insensitive to the initial magnetic topology. In framework of the Ruderman & Sutherland, vacuum gap model during this interval, non-thermal radiation is strongly suppressed. After this time, the initial (i.e. multipolar) structure begins to re-emerge through the NS crust. We distinguish three evolutionary epochs for the re-emergence process: the growth of internal toroidal field, the advection of buried poloidal field, and slow Ohmic diffusion. The efficiency of the first two stages can be enhanced when small-scale magnetic structure is present. The efficient re-emergence of high-order harmonics might significantly affect the curvature of the magnetospheric field lines in the emission zone. So, only after few 104 yr would be the NS starts shining as a pulsar again, which is in correspondence with radio silence of central compact objects. In addition, these results can explain the absence of good candidates for thermally emitting NSs with freshly re-emerged field among radio pulsars (), as NSs have time to cool down, and supernova remnants can already dissipate.

  6. Evaluation of focused multipolar stimulation for cochlear implants in acutely deafened cats

    NASA Astrophysics Data System (ADS)

    George, Shefin S.; Wise, Andrew K.; Shivdasani, Mohit N.; Shepherd, Robert K.; Fallon, James B.

    2014-12-01

    Objective. The conductive nature of the fluids and tissues of the cochlea can lead to broad activation of spiral ganglion neurons using contemporary cochlear implant stimulation configurations such as monopolar (MP) stimulation. The relatively poor spatial selectivity is thought to limit implant performance, particularly in noisy environments. Several current focusing techniques have been proposed to reduce the spread of activation with the aim towards achieving improved clinical performance. Approach. The present research evaluated the efficacy of focused multipolar (FMP) stimulation, a relatively new focusing technique in the cochlea, and compared its efficacy to both MP stimulation and tripolar (TP) stimulation. The spread of neural activity across the inferior colliculus (IC), measured by recording the spatial tuning curve, was used as a measure of spatial selectivity. Adult cats (n = 6) were acutely deafened and implanted with an intracochlear electrode array before multi-unit responses were recorded across the cochleotopic gradient of the contralateral IC. Recordings were made in response to acoustic and electrical stimulation using the MP, TP and FMP configurations. Main results. FMP and TP stimulation resulted in greater spatial selectivity than MP stimulation. However, thresholds were significantly higher (p < 0.001) for FMP and TP stimulation compared to MP stimulation. There were no differences found in spatial selectivity and threshold between FMP and TP stimulation. Significance. The greater spatial selectivity of FMP and TP stimulation would be expected to result in improved clinical performance. However, further research will be required to demonstrate the efficacy of these modes of stimulation after longer durations of deafness.

  7. Fullerene Machines

    NASA Technical Reports Server (NTRS)

    Globus, Al; Saini, Subhash

    1998-01-01

    Recent computational efforts at NASA Ames Research Center and computation and experiment elsewhere suggest that a nanotechnology of machine phase functionalized fullerenes may be synthetically accessible and of great interest. We have computationally demonstrated that molecular gears fashioned from (14,0) single-walled carbon nanotubes and benzyne teeth should operate well at 50-100 gigahertz. Preliminary results suggest that these gears can be cooled by a helium atmosphere and a laser motor can power fullerene gears if a positive and negative charge have been added to form a dipole. In addition, we have unproven concepts based on experimental and computational evidence for support structures, computer control, a system architecture, a variety of components, and manufacture. Combining fullerene machines with the remarkable mechanical properties of carbon nanotubes, there is some reason to believe that a focused effort to develop fullerene nanotechnology could yield materials with tremendous properties.

  8. Fullerene Machines

    NASA Technical Reports Server (NTRS)

    Globus, Al; Saini, Subhash (Technical Monitor)

    1998-01-01

    Fullerenes possess remarkable properties and many investigators have examined the mechanical, electronic and other characteristics of carbon SP2 systems in some detail. In addition, C-60 can be functionalized with many classes of molecular fragments and we may expect the caps of carbon nanotubes to have a similar chemistry. Finally, carbon nanotubes have been attached to t he end of scanning probe microscope (Spill) tips. Spills can be manipulated with sub-angstrom accuracy. Together, these investigations suggest that complex molecular machines made of fullerenes may someday be created and manipulated with very high accuracy. We have studied some such systems computationally (primarily functionalized carbon nanotube gears and computer components). If such machines can be combined appropriately, a class of materials may be created that can sense their environment, calculate a response, and act. The implications of such hypothetical materials are substantial.

  9. Charging machine

    DOEpatents

    Medlin, John B.

    1976-05-25

    A charging machine for loading fuel slugs into the process tubes of a nuclear reactor includes a tubular housing connected to the process tube, a charging trough connected to the other end of the tubular housing, a device for loading the charging trough with a group of fuel slugs, means for equalizing the coolant pressure in the charging trough with the pressure in the process tubes, means for pushing the group of fuel slugs into the process tube and a latch and a seal engaging the last object in the group of fuel slugs to prevent the fuel slugs from being ejected from the process tube when the pusher is removed and to prevent pressure liquid from entering the charging machine.

  10. On the possibility to detect multipolar order in URu2Si2 by the electric quadrupolar transition of resonant elastic x-ray scattering

    NASA Astrophysics Data System (ADS)

    Wang, Y. L.; Fabbris, G.; Meyers, D.; Sung, N. H.; Baumbach, R. E.; Bauer, E. D.; Ryan, P. J.; Kim, J.-W.; Liu, X.; Dean, M. P. M.; Kotliar, G.; Dai, X.

    2017-08-01

    Resonant elastic x-ray scattering is a powerful technique for measuring multipolar order parameters. In this paper, we theoretically and experimentally study the possibility of using this technique to detect the proposed multipolar order parameters in URu2Si2 at the U-L3 edge with the electric quadrupolar transition. Based on an atomic model, we calculate the azimuthal dependence of the quadrupolar transition at the U-L3 edge. The results illustrate the potential of this technique for distinguishing different multipolar order parameters. We then perform experiments on ultraclean single crystals of URu2Si2 at the U-L3 edge to search for the predicted signal, but do not detect any indications of multipolar moments within the experimental uncertainty. We theoretically estimate the orders of magnitude of the cross section and the expected count rate of the quadrupolar transition and compare them to the dipolar transitions at the U-M4 and U-L3 edges, clarifying the difficulty in detecting higher order multipolar order parameters in URu2Si2 in the current experimental setup.

  11. Machine vision

    SciTech Connect

    Horn, D.

    1989-06-01

    To keep up with the speeds of modern production lines, most machine vision applications require very powerful computers (often parallel-processing machines), which process millions of points of data in real time. The human brain performs approximately 100 billion logical floating-point operations each second. That is 400 times the speed of a Cray-1 supercomputer. The right software must be developed for parallel-processing computers. The NSF has awarded Rensselaer Polytechnic Institute (Troy, N.Y.) a $2 million grant for parallel- and image-processing software research. Over the last 15 years, Rensselaer has been conducting image-processing research, including work with high-definition TV (HDTV) and image coding and understanding. A similar NSF grant has been awarded to Michigan State University (East Lansing, Mich.) Neural networks are supposed to emulate human learning patterns. These networks and their hardware implementations (neurocomputers) show a great deal of promise for machine vision systems because they allow the systems to understand the use sensory data input more effectively. Neurocomputers excel at pattern-recognition tasks when input data are fuzzy or the vision algorithm is not optimal and is difficult to ascertain.

  12. Viruses: sophisticated biological machines.

    PubMed

    Rossmann, Michael G; Rao, Venigalla B

    2012-01-01

    Virus infection involves coordination of a series of molecular machines, including entry machines, replication machines, assembly machines, and genome packaging machines, leading to the production of infectious virions. This chapter provides an introduction to various viral molecular machines described in this book.

  13. The body-centered cubic structure of methyllithium tetramer crystal: staggered methyl conformation by electrostatic stabilization via intratetramer multipolarization.

    PubMed

    Ohta, Yusuke; Demura, Akimitsu; Okamoto, Takuya; Hitomi, Haruko; Nagaoka, Masataka

    2006-06-29

    The methyllithium tetramer (CH3Li)4 structure in the bcc crystal has been theoretically optimized with the use of density functional theory calculations under the periodic boundary condition. The X-ray structure shows that the methyl-group conformation in tetramer in crystal takes the staggered form rather than the eclipsed form that is taken in the isolated tetramer, i.e., the crystal packing effect, and this has been reproduced for the first time. It is concluded that the staggered form is advantageous in crystal, as a whole, due to the larger electrostatic stabilization via the induced intratetramer multipolarization, although it should cause, simultaneously, smaller destabilization in intratetramer electronic energy.

  14. [Morphometry of giant multipolar neurons of the brain stem reticular formation in rats on board the Kosmos-1667 biosatellite].

    PubMed

    Belichenko, P V; Leontovich, T A

    1989-05-01

    Giant multipolar neurons of nucleus reticularis gigantocellularis of rats which had been kept on board the biosatellite "Kosmos-1667" were morphometrically studied. There was a trend towards the increase in the cellular surface, the maximum diameter of dendritic field, the volume of the whole dendritic territory in the test group ad in the control experimental group kept on the earth. A reliable decrease in dendritic mass oriented to nucleus vestibularis and an increase in dendritic mass oriented to the midline were also found in test group, as compared to 3 control groups. Our data were discussed in the light of nervous tissue plasticity in adult mammals.

  15. 4-Benzoyl-3,4-dihydro-2H-1,4-benzoxazine-2-carbonitrile: refinement using a multipolar atom model.

    PubMed

    Ejsmont, Krzysztof; Joly, Jean Pierre; Wenger, Emmanuel; Guillot, Benoit; Jelsch, Christian

    2009-07-01

    The structural model for the title compound, C(16)H(12)N(2)O(2), was refined using a multipolar atom model transferred from an experimental electron-density database. The refinement showed some improvements of crystallographic statistical indices when compared with a conventional spherical neutral-atom refinement. The title compound adopts a half-chair conformation. The amide N atom lies almost in the plane defined by the three neighbouring C atoms. In the crystal structure, molecules are linked by weak intermolecular C-H...O and C-H...pi hydrogen bonds.

  16. Analysis of Multi-Polarization Switching in Vertical-Cavity Surface-Emitting Lasers Using Multi-peak gain model

    NASA Astrophysics Data System (ADS)

    Hsu, Chuan; Chen, Yu-Fong; Chin, Pei-Hou; Quadir, Shaham; Li, Yueh-Chen; Wu, Yu-Heng; Yen, Tsu-Chiang

    2013-03-01

    This research investigated the mulit-polarization switching (MPS) in vertical-cavity surface-emitting lasers (VCSELs) at constant temperature by simple multi-peak gain model.In experimental results, the phenomenon of the polarization switching (PS) in the VCSEL were arduous to definite quantitative analysis. A simple multi-peak gain model which included the temperature effect and current effect was established to match the MPS in the VCSEL. Simulation results match the experimental results well and shoe that the variation of temperature is a affecting factor of MPS. Therefore, the simple multi-peak gain model contributed a good understanding of multi-polarization switching in VCSELs.

  17. TEMPO machine

    SciTech Connect

    Rohwein, G.J.; Lancaster, K.T.; Lawson, R.N.

    1986-06-01

    TEMPO is a transformer powered megavolt pulse generator with an output pulse of 100 ns duration. The machine was designed for burst mode operation at pulse repetition rates up to 10 Hz with minimum pulse-to-pulse voltage variations. To meet the requirement for pulse duration a nd a 20-..omega.. output impedance within reasonable size constraints, the pulse forming transmission line was designed as two parallel water-insulated, strip-type Blumleins. Stray capacitance and electric fields along the edges of the line elements were controlled by lining the tank with plastic sheet.

  18. A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex.

    PubMed

    Yoshinaga, Satoshi; Ohkubo, Takahiro; Sasaki, Shinji; Nuriya, Mutsuo; Ogawa, Yukino; Yasui, Masato; Tabata, Hidenori; Nakajima, Kazunori

    2012-08-22

    In the developing mammalian cerebral cortex, excitatory neurons are generated in the ventricular zone (VZ) and subventricular zone; these neurons migrate toward the pial surface. The neurons generated in the VZ assume a multipolar morphology and remain in a narrow region called the multipolar cell accumulation zone (MAZ) for ∼24 h, in which they extend and retract multiple processes dynamically. They eventually extend an axon tangentially and begin radial migration using a migratory mode called locomotion. Despite the potential biological importance of the process movement of multipolar cells, the molecular mechanisms remain to be elucidated. Here, we observed that the processes of mouse multipolar cells were actin rich and morphologically resembled the filopodia and lamellipodia in growth cones; thus, we focused on the actin-remodeling proteins Lamellipodin (Lpd) and Ena/vasodilator-stimulated phosphoprotein (VASP). Lpd binds to phosphatidylinositol (3,4)-bisphosphate [PI(3,4)P₂] and recruits Ena/VASP, which promotes the assembly of actin filaments, to the plasma membranes. In situ hybridization and immunohistochemistry revealed that Lpd is expressed in multipolar cells in the MAZ. The functional silencing of either Lpd or Ena/VASP decreased the number of primary processes. Immunostaining and a Förster resonance energy transfer analysis revealed the subcellular localization of PI(3,4)P₂ at the tips of the processes. A knockdown experiment and treatment with an inhibitor for Src homology 2-containing inositol phosphatase-2, a 5-phosphatase that produces PI(3,4)P₂ from phosphatidylinositol (3,4,5)-triphosphate, decreased the number of primary processes. Our observations suggest that PI(3,4)P₂, Lpd, and Ena/VASP are involved in the process movement of multipolar migrating cells.

  19. Evaluation of focused multipolar stimulation for cochlear implants: a preclinical safety study

    NASA Astrophysics Data System (ADS)

    Shepherd, Robert K.; Wise, Andrew K.; Enke, Ya Lang; Carter, Paul M.; Fallon, James B.

    2017-08-01

    Objective. Cochlear implants (CIs) have a limited number of independent stimulation channels due to the highly conductive nature of the fluid-filled cochlea. Attempts to develop highly focused stimulation to improve speech perception in CI users includes the use of simultaneous stimulation via multiple current sources. Focused multipolar (FMP) stimulation is an example of this approach and has been shown to reduce interaction between stimulating channels. However, compared with conventional biphasic current pulses generated from a single current source, FMP is a complex stimulus that includes extended periods of stimulation before charge recovery is achieved, raising questions on whether chronic stimulation with this strategy is safe. The present study evaluated the long-term safety of intracochlear stimulation using FMP in a preclinical animal model of profound deafness. Approach. Six cats were bilaterally implanted with scala tympani electrode arrays two months after deafening, and received continuous unilateral FMP stimulation at levels that evoked a behavioural response for periods of up to 182 d. Electrode impedance, electrically-evoked compound action potentials (ECAPs) and auditory brainstem responses (EABRs) were monitored periodically over the course of the stimulation program from both the stimulated and contralateral control cochleae. On completion of the stimulation program cochleae were examined histologically and the electrode arrays were evaluated for evidence of platinum (Pt) corrosion. Main results. There was no significant difference in electrode impedance between control and chronically stimulated electrodes following long-term FMP stimulation. Moreover, there was no significant difference between ECAP and EABR thresholds evoked from control or stimulated cochleae at either the onset of stimulation or at completion of the stimulation program. Chronic FMP stimulation had no effect on spiral ganglion neuron (SGN) survival when compared with

  20. Induction generator powered coaxial launchers

    SciTech Connect

    Nalty, K.E.; Driga, M.D. . Dept. of Electrical and Computer Engineering)

    1991-01-01

    Most coaxial accelerator concepts to date have used switched power supplies to energize coils in the vicinity of the projectile, or have tolerated a grossly oversized power supply which energizes all coils during the course of the launch. Coordination of the switching, while engineeringly possible, provides opportunities for failure which reduces the reliability of the system as compared to a passively activated system requiring no switching. Excitation of un-used sections of a launcher dramatically reduces launch efficiency, and increases both power supply and cooling requirements. A launcher design which avoids the need for switching and automatically excites only the windings in the vicinity of the projectile is presented in this paper. The energy store for the launcher consists of rotating induction machines. The excitation for the launcher is provided by an excitation winding on the projectile, which makes the projectile act like the rotor of a synchronous condenser. This combination of super-synchronous induction machines (the energy stores) and synchronous alternators (the projectile) is called an induction generator. This paper provides a description of the induction generator powered launcher concept, and investigates scaling laws to assess the applicability of this technology for tactical and space launch applications.

  1. Hippocampal pyramidal neurons switch from a multipolar migration mode to a novel "climbing" migration mode during development.

    PubMed

    Kitazawa, Ayako; Kubo, Ken-ichiro; Hayashi, Kanehiro; Matsunaga, Yuki; Ishii, Kazuhiro; Nakajima, Kazunori

    2014-01-22

    The hippocampus plays important roles in brain functions. Despite the importance of hippocampal functions, recent analyses of neuronal migration have mainly been performed on the cerebral neocortex, and the cellular mechanisms responsible for the formation of the hippocampus are not yet completely understood. Moreover, why a prolonged time is required for hippocampal neurons to complete their migration has been unexplainable for several decades. We analyzed the migratory profile of neurons in the developing mouse hippocampal CA1 region and found that the hippocampal pyramidal neurons generated near the ventricle became postmitotic multipolar cells and accumulated in the multipolar cell accumulation zone (MAZ) in the late stage of development. The hippocampal neurons passed through the pyramidal layer by a unique mode of migration. Their leading processes were highly branched and made contact with many radial fibers. Time-lapse imaging revealed that the migrating cells changed their scaffolds from the original radial fibers to other radial fibers, and as a result they proceed in a zigzag manner, with long intervals. The migrating cells in the hippocampus reminded us of "rock climbers" that instead of using their hands to pull up their bodies were using their leading processes to pull up their cell bodies. Because this mode of migration had never been described, we called it the "climbing" mode. The change from the "climbing" mode in the hippocampus to the "locomotion" mode in the neocortex may have contributed to the brain expansion during evolution.

  2. Excitatory cortical neurons with multipolar shape establish neuronal polarity by forming a tangentially oriented axon in the intermediate zone.

    PubMed

    Hatanaka, Yumiko; Yamauchi, Kenta

    2013-01-01

    The formation of axon-dendrite polarity is crucial for neuron to make the proper information flow within the brain. Although the processes of neuronal polarity formation have been extensively studied using neurons in dissociated culture, the corresponding developmental processes in vivo are still unclear. Here, we illuminate the initial steps of morphological polarization of excitatory cortical neurons in situ, by sparsely labeling their neuroepithelial progenitors using in utero electroporation and then examining their neuronal progeny in brain sections and in slice cultures. Morphological analysis showed that an axon-like long tangential process formed in progeny cells in the intermediate zone (IZ). Time-lapse imaging analysis using slice culture revealed that progeny cells with multipolar shape, after alternately extending and retracting their short processes for several hours, suddenly elongated a long process tangentially. These cells then transformed into a bipolar shape, extending a pia-directed leading process, and migrated radially leaving the tangential process behind, which gave rise to an "L-shaped" axon. Our findings suggest that neuronal polarity in these cells is established de novo from a nonpolarized stage in vivo and indicate that excitatory cortical neurons with multipolar shape in the IZ initiate axon outgrowth before radial migration into the cortical plate.

  3. The Optical-Infared Study and Geometric Model of Young Multipolar Planetary nebula -- IRAS 21282+5050

    NASA Astrophysics Data System (ADS)

    Hsia, Chih-Hao; Chau, Wayne; Kwok, Sun

    2015-08-01

    We present high angular resolution Hubble Space Telescope (HST) optical and near-infrared imaging of the famous compact planetary nebula (PN) IRAS 21282+5050. Optical images of this object reveal several complex morphological structures including three pairs of lobes and an elliptical shell lying close to the plane of the sky. From near-infrared observations, we found a dust torus which is oriented nearly perpendicular to the major axis of elliptical shell. The results suggest that IRAS 21282+5050 (IRAS 21282) is indeed a multipolar PN, and these structures developed in the early stage on its evolutionary track. We also constructed this object by a three-dimensional (3D) model and determined the dimensions of these intrinsic structures. Assuming these lobes are shaped by wind interactions, the presence of these geometric structures has been suggested as the result of multiple phases of fast winds with temporal and directional variations. Based on the visualization of 3D model of this object viewed from different orientations, the appearance of IRAS 21282 shows similar intrinsic structures as other multipolar PNs.

  4. Application of multipolar charge models and molecular dynamics simulations to study stark shifts in inhomogeneous electric fields.

    PubMed

    Devereux, Michael; Plattner, Nuria; Meuwly, Markus

    2009-11-26

    Atomic multipole moments are used to investigate vibrational frequency shifts of CO and H(2) in uniform and inhomogeneous electric fields using ab initio calculations and Molecular Dynamics (MD) simulations. The importance of using atomic multipole moments that can accurately represent both molecular electrostatics and the vibrational response of the molecule to changes in the local electric field is highlighted. The vibrational response of CO to applied uniform and inhomogeneous electric fields is examined using Density Functional Theory calculations for a range of test fields, and the results are used to assess the performance of different atomic multipole models. In uniform fields, the calculated Stark tuning rates of Deltamu = 0.52 cm(-1)/(MV/cm) (DFT), Deltamu = 0.55 cm(-1)/(MV/cm) (fluctuating three-point charge model), and Deltamu = 0.64 cm(-1)/(MV/cm) (Multipole model up to octupole), compare favorably with the experimentally measured value of 0.67 cm(-1)/(MV/cm). For H(2), which has no permanent dipole moment, CCSD(T) calculations demonstrate the importance of bond-weakening effects in force fields in response to the applied inhomogeneous electric field. Finally, CO in hexagonal ice is considered as a test system to highlight the performance of selected multipolar models in MD simulations. The approach discussed here can be applied to calibrate a range of multipolar charge models for diatomic probes, with applications to interpret Stark spectroscopy measurements in protein active sites.

  5. Dependence of the probabilities of the electric-multipole electron transitions in W{sup 24+} on multipolarity

    SciTech Connect

    Gaigalas, Gediminas; Rudzikas, Zenonas; Rynkun, Pavel; Alkauskas, Andrius

    2011-03-15

    Usually it is accepted that the probabilities of the electric-multipole electron transitions are rapidly decreasing functions of their multipolarity. Therefore while calculating the probabilities of electronic transitions between the configurations of certain chosen parities, it seems sufficient to take into account the first nonzero term, i.e., to consider the electron transitions of lowest multipolarity permitted by the exact selection rules. This paper aims at verifying this assumption on the example of electric-octupole transitions in W{sup 24+} ion. For this purpose the large-scale multiconfiguration Hartree-Fock and Dirac-Fock calculations have been performed for the configurations [Kr]4d{sup 10}4f{sup 4} and [Kr]4d{sup 10}4f{sup 3}5s energy levels of W{sup 24+} ion. The relativistic corrections were taken into account in the quasirelativistic Breit-Pauli and fully relativistic Breit (taking into account QED effects) approximations. The role of correlation, relativistic, and QED corrections is discussed. Line strengths, oscillator strengths, and transition probabilities in Coulomb and Babushkin gauges are presented for E1 and E3 transitions among these levels.

  6. Comparative analysis of transverse intrafascicular multichannel, longitudinal intrafascicular and multipolar cuff electrodes for the selective stimulation of nerve fascicles

    NASA Astrophysics Data System (ADS)

    Badia, Jordi; Boretius, Tim; Andreu, David; Azevedo-Coste, Christine; Stieglitz, Thomas; Navarro, Xavier

    2011-06-01

    The selection of a suitable nerve electrode for neuroprosthetic applications implies a trade-off between invasiveness and selectivity, wherein the ultimate goal is achieving the highest selectivity for a high number of nerve fascicles by the least invasiveness and potential damage to the nerve. The transverse intrafascicular multichannel electrode (TIME) is intended to be transversally inserted into the peripheral nerve and to be useful to selectively activate subsets of axons in different fascicles within the same nerve. We present a comparative study of TIME, LIFE and multipolar cuff electrodes for the selective stimulation of small nerves. The electrodes were implanted on the rat sciatic nerve, and the activation of gastrocnemius, plantar and tibialis anterior muscles was recorded by EMG signals. Thus, the study allowed us to ascertain the selectivity of stimulation at the interfascicular and also at the intrafascicular level. The results of this study indicate that (1) intrafascicular electrodes (LIFE and TIME) provide excitation circumscribed to the implanted fascicle, whereas extraneural electrodes (cuffs) predominantly excite nerve fascicles located superficially; (2) the minimum threshold for muscle activation with TIME and LIFE was significantly lower than with cuff electrodes; (3) TIME allowed us to selectively activate the three tested muscles when stimulating through different active sites of one device, both at inter- and intrafascicular levels, whereas selective activation using multipolar cuff (with a longitudinal tripolar stimulation configuration) was only possible for two muscles, at the interfascicular level, and LIFE did not activate selectively more than one muscle in the implanted nerve fascicle.

  7. Incommensurate short-range multipolar order parameter of phase II in Ce3Pd20Si6

    NASA Astrophysics Data System (ADS)

    Portnichenko, P. Y.; Paschen, S.; Prokofiev, A.; Vojta, M.; Cameron, A. S.; Mignot, J.-M.; Ivanov, A.; Inosov, D. S.

    2016-12-01

    The clathrate compound Ce3Pd20Si6 is a heavy-fermion metal that exhibits magnetically hidden order at low temperatures. Reputedly, this exotic type of magnetic ground state, known as "phase II", could be associated with the ordering of Ce 4 f quadrupolar moments. In contrast to conventional (dipolar) order, it has vanishing Bragg intensity in zero magnetic field and, as a result, has escaped direct observation by neutron scattering until now. Here we report the observation of diffuse magnetic neutron scattering induced by an application of magnetic field along either the [1 1 ¯0 ] or the [001 ] direction within phase II. The broad elastic magnetic signal that surrounds the (111) structural Bragg peak can be attributed to a short-range G -type antiferromagnetic arrangement of field-induced dipoles modulated by the underlying multipolar order on the simple-cubic sublattice of Ce ions occupying the 8 c Wyckoff site. In addition, for magnetic fields applied along the [001 ] direction, the diffuse magnetic peaks in Ce3Pd20Si6 become incommensurate, suggesting a more complex modulated structure of the underlying multipolar order that can be continuously tuned by a magnetic field.

  8. Parallel machines: Parallel machine languages

    SciTech Connect

    Iannucci, R.A. )

    1990-01-01

    This book presents a framework for understanding the tradeoffs between the conventional view and the dataflow view with the objective of discovering the critical hardware structures which must be present in any scalable, general-purpose parallel computer to effectively tolerate latency and synchronization costs. The author presents an approach to scalable general purpose parallel computation. Linguistic Concerns, Compiling Issues, Intermediate Language Issues, and hardware/technological constraints are presented as a combined approach to architectural Develoement. This book presents the notion of a parallel machine language.

  9. Inductive System Health Monitoring

    NASA Technical Reports Server (NTRS)

    Iverson, David L.

    2004-01-01

    The Inductive Monitoring System (IMS) software was developed to provide a technique to automatically produce health monitoring knowledge bases for systems that are either difficult to model (simulate) with a computer or which require computer models that are too complex to use for real time monitoring. IMS uses nominal data sets collected either directly from the system or from simulations to build a knowledge base that can be used to detect anomalous behavior in the system. Machine learning and data mining techniques are used to characterize typical system behavior by extracting general classes of nominal data from archived data sets. IMS is able to monitor the system by comparing real time operational data with these classes. We present a description of learning and monitoring method used by IMS and summarize some recent IMS results.

  10. Mining machine

    SciTech Connect

    Becker, H.R.

    1984-12-04

    A mining machine is disclosed comprising a mobile base and a cutting head assembly at a forward end of the mobile base having a cutter drum rotatable about an output shaft disposed along the longitudinal axis of the cutter drum. A drive system for the cutting head assembly comprises at least one motor for driving at least one toothed motor pinion and a generally cylindrical combination gear having generally circular end surfaces. A bevel or face gear is formed in at least one of the end surfaces, having teeth adapted to mate with and be driven by the toothed motor pinion. The combination gear has a worm gear formed in the outside cylindrical surface, which is disposed in driving engagement with the teeth of an output gear integrally and coaxially connected to the output shaft of the cutter drum.

  11. The Importance of Why: An Intelligence Approach for a Multi-Polar World

    DTIC Science & Technology

    2016-04-04

    ADDRESS(ES) Joint Forces Staff College Joint Advanced Warfighting School 7800 Hampton Blvd Norfolk, VA 23511-1702 8. PERFORMING ORGANIZATION REPORT...characteristics, the Joint Force must educate intelligence practitioners in complexity theory, advance inductive and abductive cognitive methods...This page intentionally left blank. NATIONAL DEFENSE UNIVERSITY JOINT FORCES STAFF COLLEGE

  12. Machine musicianship

    NASA Astrophysics Data System (ADS)

    Rowe, Robert

    2002-05-01

    The training of musicians begins by teaching basic musical concepts, a collection of knowledge commonly known as musicianship. Computer programs designed to implement musical skills (e.g., to make sense of what they hear, perform music expressively, or compose convincing pieces) can similarly benefit from access to a fundamental level of musicianship. Recent research in music cognition, artificial intelligence, and music theory has produced a repertoire of techniques that can make the behavior of computer programs more musical. Many of these were presented in a recently published book/CD-ROM entitled Machine Musicianship. For use in interactive music systems, we are interested in those which are fast enough to run in real time and that need only make reference to the material as it appears in sequence. This talk will review several applications that are able to identify the tonal center of musical material during performance. Beyond this specific task, the design of real-time algorithmic listening through the concurrent operation of several connected analyzers is examined. The presentation includes discussion of a library of C++ objects that can be combined to perform interactive listening and a demonstration of their capability.

  13. Machine wanting.

    PubMed

    McShea, Daniel W

    2013-12-01

    Wants, preferences, and cares are physical things or events, not ideas or propositions, and therefore no chain of pure logic can conclude with a want, preference, or care. It follows that no pure-logic machine will ever want, prefer, or care. And its behavior will never be driven in the way that deliberate human behavior is driven, in other words, it will not be motivated or goal directed. Therefore, if we want to simulate human-style interactions with the world, we will need to first understand the physical structure of goal-directed systems. I argue that all such systems share a common nested structure, consisting of a smaller entity that moves within and is driven by a larger field that contains it. In such systems, the smaller contained entity is directed by the field, but also moves to some degree independently of it, allowing the entity to deviate and return, to show the plasticity and persistence that is characteristic of goal direction. If all this is right, then human want-driven behavior probably involves a behavior-generating mechanism that is contained within a neural field of some kind. In principle, for goal directedness generally, the containment can be virtual, raising the possibility that want-driven behavior could be simulated in standard computational systems. But there are also reasons to believe that goal-direction works better when containment is also physical, suggesting that a new kind of hardware may be necessary. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Laser transmitter design and performance for the slope imaging multi-polarization photon-counting lidar (SIMPL) instrument

    NASA Astrophysics Data System (ADS)

    Yu, Anthony W.; Harding, David J.; Dabney, Philip W.

    2016-03-01

    The Slope Imaging Multi-polarization Photon-counting Lidar (SIMPL) is a polarimetric, two-color, multi-beam push broom laser altimeter developed through the NASA Earth Science Technology Office Instrument Incubator Program. It has flown successfully on multiple airborne platforms beginning in 2008.1 It was developed to demonstrate new altimetry capabilities that combine height measurements and information about surface composition and properties. In this talk we will discuss the laser transmitter design and performance and present recent science data collected over the Greenland ice sheet and arctic sea ice in support of the second NASA Ice Cloud and land Elevation Satellite (ICESat-2) mission to be launched in 2017.2

  15. NDUFV2 regulates neuronal migration in the developing cerebral cortex through modulation of the multipolar-bipolar transition.

    PubMed

    Chen, Tianda; Wu, Qinwei; Zhang, Yang; Zhang, Dai

    2015-11-02

    Abnormalities during brain development are tightly linked several psychiatric disorders. Mutations in NADH dehydrogenase ubiquinone flavoprotein 2 (NDUFV2) are responsible for schizophrenia, bipolar disorder and Parkinson׳s disease. However, the function of NDUFV2 during brain development remains unclear. Here we reported that ndufv2 is expressed in the developing cerebral cortex. In utero suppression of ndufv2 arrested neuronal migration, leading to accumulation of ectopic neurons in the intermediate zone. ndufv2 inhibition did not affect radial glia scaffold, progenitor cells or neurons survival. However, the loss of ndufv2 impairs neuronal multipolar-bipolar transition in vivo and polarization in vitro. Moreover, ndufv2 affected actin cytoskeleton and tubulin stabilization in cortical neurons. Overall, our findings establish a new NDUFV2 dependent mechanism underlying neuronal migration and psychiatric disorders.

  16. Multipolar theory of blackbody radiation shift of atomic energy levels and its implications for optical lattice clocks

    SciTech Connect

    Porsev, Sergey G.; Derevianko, Andrei

    2006-08-15

    Blackbody radiation (BBR) shifts of the {sup 3}P{sub 0}-{sup 1}S{sub 0} clock transition in the divalent atoms Mg, Ca, Sr, and Yb are evaluated. The dominant electric-dipole contributions are computed using accurate relativistic many-body techniques of atomic structure. At room temperatures, the resulting uncertainties in the E1 BBR shifts are large and substantially affect the projected 10{sup -18} fractional accuracy of the optical-lattice-based clocks. A peculiarity of these clocks is that the characteristic BBR wavelength is comparable to the {sup 3}P fine-structure intervals. To evaluate relevant M1 and E2 contributions, a theory of multipolar BBR shifts is developed. The resulting corrections, although presently masked by the uncertainties in the E1 contribution, are required at the 10{sup -18} accuracy goal.

  17. Flotation machine

    SciTech Connect

    Zlobin, M.N.; Permyakov, G.P.; Nemarov, A.A.; Metsik, V.M.; Medetsky, J.V.; Taraban, N.T.

    1993-08-10

    A flotation machine is described for beneficiating minerals comprising: a vertical cylindrical chamber for circulating a flotation pulp; a downwardly tapered bottom connected to said vertical cylindrical chamber; feed pipe means for feeding the flotation pulp carrying mineral particles of fine fraction, particles of the useful ingredient of the fine fraction being capable of floating up from the volume of said aerated pulp; discharge pipe means connected to the tapered bottom near its lowest point for discharging gangue; an annular trough for collecting froth concentrate at the top of said chamber; a group of frustoconical shells each having bases of different diameters and a tapered surface secured axially in said chamber and spaced equidistantly from one another height wise of said chamber; aerator means for aerating the flotation pulp secured to the walls of said chamber and communicating therewith to provide aerated water into said chamber; means for feeding mineral particles of coarse fraction, particles of the useful ingredient of the coarse fraction being capable of floating in the froth layer of the flotation pulp, in the form of a hydrocyclone having a cylindrical casing positioned axially over said chamber and a downwardly tapering outlet directed downwardly to feed the coarse particles to said chamber; feed pipe means for feeding the flotation pulp carrying mineral particles of coarse fraction positioned tangentially at said cylindrical casing of the hydrocyclone; and evacuation means for evacuating the liquid phase of the flotation pulp positioned tangentially at said casing of the hydrocyclone over said feed pipe means and connected to said feed pipe means for feeding the flotation pulp carrying mineral particles of the fine fraction.

  18. v-Src-induced nuclear localization of YAP is involved in multipolar spindle formation in tetraploid cells.

    PubMed

    Kakae, Keiko; Ikeuchi, Masayoshi; Kuga, Takahisa; Saito, Youhei; Yamaguchi, Naoto; Nakayama, Yuji

    2017-01-01

    The protein-tyrosine kinase, c-Src, is involved in a variety of signaling events, including cell division. We have reported that v-Src, which is a mutant variant of the cellular proto-oncogene, c-Src, causes delocalization of Aurora B kinase, resulting in a furrow regression in cytokinesis and the generation of multinucleated cells. However, the effect of v-Src on mitotic spindle formation is unknown. Here we show that v-Src-expressing HCT116 and NIH3T3 cells undergo abnormal cell division, in which cells separate into more than two cells. Upon v-Src expression, the proportion of multinucleated cells is increased in a time-dependent manner. Flow cytometry analysis revealed that v-Src increases the number of cells having a ≥4N DNA content. Microscopic analysis showed that v-Src induces the formation of multipolar spindles with excess centrosomes. These results suggest that v-Src induces multipolar spindle formation by generating multinucleated cells. Tetraploidy activates the tetraploidy checkpoint, leading to a cell cycle arrest of tetraploid cells at the G1 phase, in which the nuclear exclusion of the transcription co-activator YAP plays a critical role. In multinucleated cells that are induced by cytochalasin B and the Plk1 inhibitor, YAP is excluded from the nucleus. However, v-Src prevents this nuclear exclusion of YAP through a decrease in the phosphorylation of YAP at Ser127 in multinucleated cells. Furthermore, v-Src decreases the expression level of p53, which also plays a critical role in the cell cycle arrest of tetraploid cells. These results suggest that v-Src promotes abnormal spindle formation in at least two ways: generation of multinucleated cells and a weakening of the tetraploidy checkpoint.

  19. Applied machine vision

    SciTech Connect

    Not Available

    1984-01-01

    This book presents the papers given at a conference on robot vision. Topics considered at the conference included the link between fixed and flexible automation, general applications of machine vision, the development of a specification for a machine vision system, machine vision technology, machine vision non-contact gaging, and vision in electronics manufacturing.

  20. Machine Shop Lathes.

    ERIC Educational Resources Information Center

    Dunn, James

    This guide, the second in a series of five machine shop curriculum manuals, was designed for use in machine shop courses in Oklahoma. The purpose of the manual is to equip students with basic knowledge and skills that will enable them to enter the machine trade at the machine-operator level. The curriculum is designed so that it can be used in…

  1. Time (hole?) machines

    NASA Astrophysics Data System (ADS)

    Manchak, John Byron

    2014-11-01

    Within the context of general relativity, we consider a type of "time machine" and introduce the related "hole machine". We review what is known about each and add results of our own. We conclude that (so far) the hole machine advocate is in a better position than the time machine advocate.

  2. [Leak of anesthetic gases inside the anesthesia machine].

    PubMed

    Tanaka, Tadashi; Masaki, Go; Kato, Hidetaka; Takita, Eiichi; Sugai, Naosuke

    2006-05-01

    We experienced the leak of anesthetic gases inside the anesthesia machine in spite of performing the leak test before its use. After induction of anesthesia, a laryngeal mask airway was inserted and the patient was ventilated manually. At the beginning we could not find any signs of machine troubles. High airway pressure occurred immediately after switching to the mechanical ventilation. Because we could not detect the details of the machine trouble, tidal volume was set lower and the surgery was continued. After surgery, we found a crack in a fresh gas circuit valve. We have to check the anesthesia machine regularly and know its duration of use.

  3. 3MI: The Multi-Viewing Multi-Channel Multi-Polarization Imaging Mission of the EUMETSAT Polar System - Second Generation (EPS-SG) dedicated to aerosol characterization

    NASA Astrophysics Data System (ADS)

    Marbach, Thierry; Phillips, Pepe; Schlüssel, Peter

    2013-05-01

    The EPS-SG Multi-Viewing Multi-Channel Multi-Polarization Imaging Mission (3MI) is a radiometer dedicated to aerosol characterization for climate monitoring, air quality forecasts and Numerical Weather Prediction (NWP). The purpose of the 3MI concept, likewise that of the heritage missions POLarization and Directionality of the Earth's Reflectances (POLDER) and Polarization & Anisotropy of Reflectances for Atmospheric Sciences coupled with Observations from a Lidar (PARASOL), is to reconstruct a multi-spectral (from 410 to 2130 nm), multi-polarization (-60°, 0°, and +60°), and multi-angular (14 views) image of the Earth outgoing radiance at the top of the atmosphere (TOA) in order to resolve the directional anisotropy and the microphysical properties of aerosol.

  4. The 5'-flanking region of the RP58 coding sequence shows prominent promoter activity in multipolar cells in the subventricular zone during corticogenesis.

    PubMed

    Ohtaka-Maruyama, C; Hirai, S; Miwa, A; Takahashi, A; Okado, H

    2012-01-10

    Pyramidal neurons of the neocortex are produced from progenitor cells located in the neocortical ventricular zone (VZ) and subventricular zone (SVZ) during embryogenesis. RP58 is a transcriptional repressor that is strongly expressed in the developing brain and plays an essential role in corticogenesis. The expression of RP58 is strictly regulated in a time-dependent and spatially restricted manner. It is maximally expressed in E15-16 embryonic cerebral cortex, localized specifically to the cortical plate and SVZ of the neocortex, hippocampus, and parts of amygdala during brain development, and found in glutamatergic but not GABAergic neurons. Identification of the promoter activity underlying specific expression patterns provides important clues to their mechanisms of action. Here, we show that the RP58 gene promoter is activated prominently in multipolar migrating cells, the first in vivo analysis of RP58 promoter activity in the brain. The 5.3 kb 5'-flanking genomic DNA of the RP58 coding region demonstrates promoter activity in neurons both in vitro and in vivo. This promoter is highly responsive to the transcription factor neurogenin2 (Ngn2), which is a direct upstream activator of RP58 expression. Using in utero electroporation, we demonstrate that RP58 gene promoter activity is first detected in a subpopulation of pin-like VZ cells, then prominently activated in migrating multipolar cells in the multipolar cell accumulation zone (MAZ) located just above the VZ. In dissociated primary cultured cortical neurons, RP58 promoter activity mimics in vivo expression patterns from a molecular standpoint that RP58 is expressed in a fraction of Sox2-positive progenitor cells, Ngn2-positive neuronal committed cells, and Tuj1-positive young neurons, but not in Dlx2-positive GABAergic neurons. Finally, we show that Cre recombinase expression under the control of the RP58 gene promoter is a feasible tool for conditional gene switching in post-mitotic multipolar migrating

  5. [Modulating effect of dopamine on amplitude of GABA-produced chemocontrolled currents in multipolar spinal cord neurons of ammocaete].

    PubMed

    Bukinich, A A

    2010-01-01

    By using the patch-clamp method in the whole cell configuration, modulating effect of dopamine on GABA-activated currents has been studied on isolated multipolar spinal cord neurons of the ammocaete (larva of the lamprey Lampetra planeri). At application of dopamine (5 microM), there was observed in some cases a decrease of the GABA-activated current, on average, by 33.3 +/- 8.7 (n = 8, p < 0.01), in other cases--an increase of the amplitude, on average, by 37.3 +/- 11.8% (n = 5, p < 0.01). Concentration of GABA amounted to 2 mM. Study of action of agonists of D1- and D2-receptors on amplitude of che-mocontrolled currents has shown that agonist of D1-receptors (+)-SKF-38393 (5 microM) decreases the GABA-activated current amplitude, on average, by 63.1 +/- 11.7% (n = 8, p < 0.01); the agonist of D2-receptors (-)-quinpirole (5 microM) produces in various cells the dopamine-like effects: an increase of the GABA-activated current amplitude, on average, by 61.0 +/- 13.8% (n = 8, p < 0.01) and a decrease of amplitude, on average, by 55.7 +/- 2.0 % (n = 6, p < 0.01). It has been shown that antagonist of D2-receptors sulpiride (5 microM) does not block effects produced by dopamine. The dopamine effects were partially blocked by antagonist of D1-receptors (+)-SCH-23390 (5 microM): a decrease of the GABA-activated amplitude current amounted, on average, to 11.7 +/- 1.8 % (n = 7, p < 0.01), while an increase of amplitude--8.3 +/- 2.0 % (n = 5,p < 0.01). At the same time, effects of agonist of D1-receptors quinpirole (5 microM) were partially blocked by antagonist of D1-receptors (+)-SCH-23390: a decrease of the GABA-activated current amplitude amounted, on average, to 9.2 +/- 3.4 % (n = 6, p < 0.01) and an increase of amplitude--6.3 +/- 1.8 % (n = 10, p < 0.01). The obtained data indicate differences of mechanisms of the receptor-mediated effect of agonists of dopamine receptors on GABA-activated and potential-activated currents of multipolar neurons of the ammocaete spinal

  6. The development and migration of large multipolar neurons into the cochlear nucleus of the North American opossum.

    PubMed

    Willard, F H; Martin, G F

    1986-06-01

    We have studied the maturation of the inferior colliculus and cochlear nuclei of the North American opossum with particular emphasis on the large multipolar neurons of the cochlear nucleus. These neurons include the principal and giant cells of the dorsal cochlear nucleus (DCN) and the large neurons of the ventral cochlear nucleus (VCN), all of which can be labelled by horseradish peroxidase (HRP) injections into the contralateral inferior colliculus (IC). The size of these neurons, their characteristic Nissl patterns, and their labelling density after injections into the IC render them distinguishable from other neurons in this nuclei, even in young animals. In Nissl-stained sections of newborn opossums, a band of horizontally oriented neurons can be identified dorsomedial to the vestibular nerve root. This band extends from an apparent cytogenetic zone close to the sulcus limitans, to, but not within, the presumptive cochlear nucleus. Between birth and estimated postnatal day 22 (EPND 22) the band shifts laterally, eventually becoming incorporated into the cochlear nucleus. Many neurons in this band have perinuclear caps of Nissl substance similar to those present in the principal cells of the adult DCN. Injections of HRP into the IC as early as EPND 5 (17 days after conception) labelled neurons in the band referred to above but not in the presumptive cochlear nucleus. By EPND 15, labelled cells were clustered mainly within the nucleus proper. Most of these cells were located in the DCN, but a few were scattered in the dorsocentral VCN. Consistent labelling of small neurons in VCN was not obtained until sometime later. From EPND 15 to EPND 20 most of the labelled cells in DCN reoriented in the vertical plane, aligned in layer II, and differentiated into principal neurons. Some, however, remained deep to layer II and differentiated into giant neurons. The heavily labelled cells in VCN differentiated into large neurons. Our results suggest that the large multipolar

  7. Tube Alinement for Machining

    NASA Technical Reports Server (NTRS)

    Garcia, J.

    1984-01-01

    Tool with stepped shoulders alines tubes for machining in preparation for welding. Alinement with machine tool axis accurate to within 5 mils (0.13mm) and completed much faster than visual setup by machinist.

  8. Women, Men, and Machines.

    ERIC Educational Resources Information Center

    Form, William; McMillen, David Byron

    1983-01-01

    Data from the first national study of technological change show that proportionately more women than men operate machines, are more exposed to machines that have alienating effects, and suffer more from the negative effects of technological change. (Author/SSH)

  9. Stirling machine operating experience

    NASA Technical Reports Server (NTRS)

    Ross, Brad; Dudenhoefer, James E.

    1991-01-01

    Numerous Stirling machines have been built and operated, but the operating experience of these machines is not well known. It is important to examine this operating experience in detail, because it largely substantiates the claim that Stirling machines are capable of reliable and lengthy lives. The amount of data that exists is impressive, considering that many of the machines that have been built are developmental machines intended to show proof of concept, and were not expected to operate for any lengthy period of time. Some Stirling machines (typically free-piston machines) achieve long life through non-contact bearings, while other Stirling machines (typically kinematic) have achieved long operating lives through regular seal and bearing replacements. In addition to engine and system testing, life testing of critical components is also considered.

  10. Unified approach to multipolar polarisation and charge transfer for ions: microhydrated Na+.

    PubMed

    Mills, Matthew J L; Hawe, Glenn I; Handley, Christopher M; Popelier, Paul L A

    2013-11-07

    Electrostatic effects play a large part in determining the properties of chemical systems. In addition, a treatment of the polarisation of the electron distribution is important for many systems, including solutions of monatomic ions. Typically employed methods for describing polarisable electrostatics use a number of approximations, including atom-centred point charges and polarisation methods that require iterative calculation on the fly. We present a method that treats charge transfer and polarisation on an equal footing. Atom-centred multipole moments describe the charge distribution of a chemical system. The variation of these multipole moments with the geometry of the surrounding atoms is captured by the machine learning method kriging. The interatomic electrostatic interaction can be computed using the resulting predicted multipole moments. This allows the treatment of both intra- and interatomic polarisation with the same method. The proposed method does not return explicit polarisabilities but instead, predicts the result of the polarisation process. An application of this new method to the sodium cation in a water environment is described. The performance of the method is assessed by comparison of its predictions of atomic multipole moments and atom-atom electrostatic interaction energies to exact results. The kriging models are able to predict the electrostatic interaction energy between the ion and all water atoms within 4 kJ mol(-1) for any of the external test set Na(+)(H2O)6 configurations.

  11. WAVE2-Abi2 complex controls growth cone activity and regulates the multipolar-bipolar transition as well as the initiation of glia-guided migration.

    PubMed

    Xie, Min-Jue; Yagi, Hideshi; Kuroda, Kazuki; Wang, Chen-Chi; Komada, Munekazu; Zhao, Hong; Sakakibara, Akira; Miyata, Takaki; Nagata, Koh-Ichi; Oka, Yuichiro; Iguchi, Tokuichi; Sato, Makoto

    2013-06-01

    Glia-guided migration (glia-guided locomotion) during radial migration is a characteristic yet unique mode of migration. In this process, the directionality of migration is predetermined by glial processes and not by growth cones. Prior to the initiation of glia-guided migration, migrating neurons transform from multipolar to bipolar, but the molecular mechanisms underlying this multipolar-bipolar transition and the commencement of glia-guided migration are not fully understood. Here, we demonstrate that the multipolar-bipolar transition is not solely a cell autonomous event; instead, the interaction of growth cones with glial processes plays an essential role. Time-lapse imaging with lattice assays reveals the importance of vigorously active growth cones in searching for appropriate glial scaffolds, completing the transition, and initiating glia-guided migration. These growth cone activities are regulated by Abl kinase and Cdk5 via WAVE2-Abi2 through the phosphorylation of tyrosine 150 and serine 137 of WAVE2. Neurons that do not display such growth cone activities are mispositioned in a more superficial location in the neocortex, suggesting the significance of growth cones for the final location of the neurons. This process occurs in spite of the "inside-out" principle in which later-born neurons are situated more superficially.

  12. The Iowa wave machines

    NASA Astrophysics Data System (ADS)

    Daffron, John D.; Greenslade, Thomas B.; Stille, Dale

    2010-03-01

    Wave machines are a staple of demonstration lectures, and a good pair of wave machines can make the idea of transverse and longitudinal waves clearly evident to students. The demonstration apparatus collection of the University of Iowa contains examples of transverse and longitudinal wave machines that will be of interest to readers of The Physics Teacher. These machines probably date from about 1925 and may have been locally produced. You too can build them.

  13. Your Sewing Machine.

    ERIC Educational Resources Information Center

    Peacock, Marion E.

    The programed instruction manual is designed to aid the student in learning the parts, uses, and operation of the sewing machine. Drawings of sewing machine parts are presented, and space is provided for the student's written responses. Following an introductory section identifying sewing machine parts, the manual deals with each part and its…

  14. Automatic Inspection During Machining

    NASA Technical Reports Server (NTRS)

    Ransom, Clyde L.

    1988-01-01

    In experimental manufacturing process, numerically-controlled machine tool temporarily converts into inspection machine by installing electronic touch probes and specially-developed numerical-control software. Software drives probes in paths to and on newly machined parts and collects data on dimensions of parts.

  15. Apprentice Machine Theory Outline.

    ERIC Educational Resources Information Center

    Connecticut State Dept. of Education, Hartford. Div. of Vocational-Technical Schools.

    This volume contains outlines for 16 courses in machine theory that are designed for machine tool apprentices. Addressed in the individual course outlines are the following topics: basic concepts; lathes; milling machines; drills, saws, and shapers; heat treatment and metallurgy; grinders; quality control; hydraulics and pneumatics;…

  16. Machining lead wafers

    SciTech Connect

    Schamaun, R.T.

    1987-09-01

    Recently, MEC-6 machined some 4-inch-diameter lead wafers to precision tolerances. The tolerance on the wafer thickness was +-0.000080 inch. A diamond tool was used to machine the wafers on a Moore No. 3 lathe. This report discusses the methods used to machine the wafers, the fixtures used to hold the wafers, and the inspection methods and results.

  17. Cable-Twisting Machine

    NASA Technical Reports Server (NTRS)

    Kurnett, S.

    1982-01-01

    New cable-twisting machine is smaller and faster than many production units. Is useful mainly in production of short-run special cables. Already-twisted cable can be fed along axis of machine. Faster operation than typical industrial cable-twisting machines possible by using smaller spools of wire.

  18. Induction generator-induction motor wind-powered pumping system

    SciTech Connect

    Miranda, M.S.; Lyra, R.O.C.; Silva, S.R.

    1997-12-31

    The energy storage matter plays an important role in wind-electric conversion systems for isolated applications. Having that in mind, two different approaches can be basically considered: either the immediate conversion of the generated electric energy, as in a water pumping system or electric energy storage for later use, as in a battery charging system. Due to some features such as no need of an external reactive power source and, sometimes, a gearbox, permanent-magnet synchronous generators have been broadly used in low rated power isolated systems. Despite that, system performance can be affected when the generator is feeding an inductive load (e.g., an induction motor) under variable-speed-variable-frequency operational conditions. Since there is no effective flux control, motor overload may occur at high wind speeds. Thus, good system performance can be obtained through additional control devices which may increase system cost. Although being rugged and cheap, induction machines always work as a reactive power drain; therefore, they demand an external reactive power source. Considering that, reactive static compensators appear as an attractive alternative to the cost x performance problem. In addition to that, different control strategies can be used so that system performance can be improved.

  19. Realistic sampling of amino acid geometries for a multipolar polarizable force field

    PubMed Central

    Hughes, Timothy J.; Cardamone, Salvatore

    2015-01-01

    The Quantum Chemical Topological Force Field (QCTFF) uses the machine learning method kriging to map atomic multipole moments to the coordinates of all atoms in the molecular system. It is important that kriging operates on relevant and realistic training sets of molecular geometries. Therefore, we sampled single amino acid geometries directly from protein crystal structures stored in the Protein Databank (PDB). This sampling enhances the conformational realism (in terms of dihedral angles) of the training geometries. However, these geometries can be fraught with inaccurate bond lengths and valence angles due to artefacts of the refinement process of the X‐ray diffraction patterns, combined with experimentally invisible hydrogen atoms. This is why we developed a hybrid PDB/nonstationary normal modes (NM) sampling approach called PDB/NM. This method is superior over standard NM sampling, which captures only geometries optimized from the stationary points of single amino acids in the gas phase. Indeed, PDB/NM combines the sampling of relevant dihedral angles with chemically correct local geometries. Geometries sampled using PDB/NM were used to build kriging models for alanine and lysine, and their prediction accuracy was compared to models built from geometries sampled from three other sampling approaches. Bond length variation, as opposed to variation in dihedral angles, puts pressure on prediction accuracy, potentially lowering it. Hence, the larger coverage of dihedral angles of the PDB/NM method does not deteriorate the predictive accuracy of kriging models, compared to the NM sampling around local energetic minima used so far in the development of QCTFF. © 2015 The Authors. Journal of Computational Chemistry Published by Wiley Periodicals, Inc. PMID:26235784

  20. Realistic sampling of amino acid geometries for a multipolar polarizable force field.

    PubMed

    Hughes, Timothy J; Cardamone, Salvatore; Popelier, Paul L A

    2015-09-15

    The Quantum Chemical Topological Force Field (QCTFF) uses the machine learning method kriging to map atomic multipole moments to the coordinates of all atoms in the molecular system. It is important that kriging operates on relevant and realistic training sets of molecular geometries. Therefore, we sampled single amino acid geometries directly from protein crystal structures stored in the Protein Databank (PDB). This sampling enhances the conformational realism (in terms of dihedral angles) of the training geometries. However, these geometries can be fraught with inaccurate bond lengths and valence angles due to artefacts of the refinement process of the X-ray diffraction patterns, combined with experimentally invisible hydrogen atoms. This is why we developed a hybrid PDB/nonstationary normal modes (NM) sampling approach called PDB/NM. This method is superior over standard NM sampling, which captures only geometries optimized from the stationary points of single amino acids in the gas phase. Indeed, PDB/NM combines the sampling of relevant dihedral angles with chemically correct local geometries. Geometries sampled using PDB/NM were used to build kriging models for alanine and lysine, and their prediction accuracy was compared to models built from geometries sampled from three other sampling approaches. Bond length variation, as opposed to variation in dihedral angles, puts pressure on prediction accuracy, potentially lowering it. Hence, the larger coverage of dihedral angles of the PDB/NM method does not deteriorate the predictive accuracy of kriging models, compared to the NM sampling around local energetic minima used so far in the development of QCTFF.

  1. The vapor-liquid interface potential of (multi)polar fluids and its influence on ion solvation.

    PubMed

    Horváth, Lorand; Beu, Titus; Manghi, Manoel; Palmeri, John

    2013-04-21

    The interface between the vapor and liquid phase of quadrupolar-dipolar fluids is the seat of an electric interfacial potential whose influence on ion solvation and distribution is not yet fully understood. To obtain further microscopic insight into water specificity we first present extensive classical molecular dynamics simulations of a series of model liquids with variable molecular quadrupole moments that interpolates between SPC/E water and a purely dipolar liquid. We then pinpoint the essential role played by the competing multipolar contributions to the vapor-liquid and the solute-liquid interface potentials in determining an important ion-specific direct electrostatic contribution to the ionic solvation free energy for SPC/E water-dominated by the quadrupolar and dipolar parts-beyond the dominant polarization one. Our results show that the influence of the vapor-liquid interfacial potential on ion solvation is strongly reduced due to the strong partial cancellation brought about by the competing solute-liquid interface potential.

  2. Automated Wetland Delineation from Multi-Frequency and Multi-Polarized SAR Images in High Temporal and Spatial Resolution

    NASA Astrophysics Data System (ADS)

    Moser, L.; Schmitt, A.; Wendleder, A.

    2016-06-01

    Water scarcity is one of the main challenges posed by the changing climate. Especially in semi-arid regions where water reservoirs are filled during the very short rainy season, but have to store enough water for the extremely long dry season, the intelligent handling of water resources is vital. This study focusses on Lac Bam in Burkina Faso, which is the largest natural lake of the country and of high importance for the local inhabitants for irrigated farming, animal watering, and extraction of water for drinking and sanitation. With respect to the competition for water resources an independent area-wide monitoring system is essential for the acceptance of any decision maker. The following contribution introduces a weather and illumination independent monitoring system for the automated wetland delineation with a high temporal (about two weeks) and a high spatial sampling (about five meters). The similarities of the multispectral and multi-polarized SAR acquisitions by RADARSAT-2 and TerraSAR-X are studied as well as the differences. The results indicate that even basic approaches without pre-classification time series analysis or post-classification filtering are already enough to establish a monitoring system of prime importance for a whole region.

  3. Numerical simulation and performance improvement of a multi-polar concentric Halbach cylindrical magnet for magnetic refrigeration

    NASA Astrophysics Data System (ADS)

    You, Yonghua; Guo, Yue; Xiao, Shuifang; Yu, Shen; Ji, Hu; Luo, Xiaobing

    2016-05-01

    Multi-polar concentric Halbach cylinders of magnets could generate the magnetic field varying considerably in the annular gaps, thus were applied in the rotary magnetic refrigerators. In the current investigation, a six-polar concentric Halbach cylinder is developed based on the ideal concentric one by the numerical simulation with COMSOL Multiphysics. Cylinder radii are optimized and magnet material profiles are adjusted for a better overall performance (Λcool). Moreover, the segmentation on the concentric cylinder is conducted for an easy fabrication, and the edge effect of finite-length device is studied. With the present investigation, it is found that a larger external radius of external cylinder facilitates a larger flux density in the high field region (| B | bar high), while Λcool could be worse. Meanwhile, with the removal of magnet materials enclosed by the equipotential lines of magnetic vector potential, the magnetic flux density in low field region (| B | bar low) drops from 0.271 to 0.0136 T, and Λcool rises from 1.36 to 1.85 T0.7. Moreover, a proper segmentation would not degrade the difference between | B | bar high and | B | bar low, on the contrary, Λcool rises by about 20.2% due to magnet materials lack for efficiency replaced by soft irons. Finally, current 3D simulation indicates the edge effect on Λcool could be trivial.

  4. Change vector analysis method for inundation change detection using multi-temporal multi-polarized SAR images

    NASA Astrophysics Data System (ADS)

    Shen, Guozhuang; Guo, Huadong; Liao, Jingjuan

    2007-11-01

    With the all-weather and day-night imaging capability, synthetic aperture radar (SAR) plays an important role in inundation extent change detection. Inundation extent change detection using SAR will be easy as a result of the dark image tones yielded by specular reflection. Change vector analysis (CVA) method, an effective change detection method, is also a valuable inundation extent change detection method. In CVA method, change magnitude and change direction can be generated separately, which can be used to determine change areas and change types. CVA method also has the ability to process any number of spectral bands and to produce detailed change information. In this paper, CVA method was applied to inundation extent change detection using multi-temporal multi-polarization ENVISAT ASAR alternative polarization images acquired on 2004-08-29, 2004-12-12 and 2005-03-27. The test site is located in Poyang Lake wetland, where land surface had different inundation extent when images were acquired. Firstly these 3 phases of images were registered together. Then the change vectors were calculated using these images. After that change magnitude and direction cosine images were produced. At last the change areas and the corresponding change type were extracted separately using decision tree method. The result indicates that CVA method has potential utility in inundation extent change detection.

  5. Multipolar phases and magnetically hidden order: review of the heavy-fermion compound Ce1-x La x B6.

    PubMed

    Cameron, Alistair S; Friemel, Gerd; Inosov, Dmytro S

    2016-06-01

    Cerium hexaboride is a cubic f-electron heavy-fermion compound that displays a rich array of low-temperature magnetic ordering phenomena which have been the subject of investigation for more than 50 years. Its complex behaviour is the result of competing interactions, with both itinerant and local electrons playing important roles. Investigating this material has proven to be a substantial challenge, in particular because of the appearance of a 'magnetically hidden order' phase, which remained elusive to neutron-scattering investigations for many years. It was not until the development of modern x-ray scattering techniques that the long suspected multipolar origin of this phase was confirmed. Doping with non-magnetic lanthanum dilutes the magnetic cerium sublattice and reduces the f-electron count, bringing about substantial changes to the ground state with the emergence of new phases and quantum critical phenomena. To this day, Ce1-x La x B6 and its related compounds remain a subject of intense interest. Despite the substantial progress in understanding their behaviour, they continue to reveal new and unexplained physical phenomena. Here we present a review of the accumulated body of knowledge on this family of materials in order to provide a firm standpoint for future investigations.

  6. Quantum machine learning

    NASA Astrophysics Data System (ADS)

    Biamonte, Jacob; Wittek, Peter; Pancotti, Nicola; Rebentrost, Patrick; Wiebe, Nathan; Lloyd, Seth

    2017-09-01

    Fuelled by increasing computer power and algorithmic advances, machine learning techniques have become powerful tools for finding patterns in data. Quantum systems produce atypical patterns that classical systems are thought not to produce efficiently, so it is reasonable to postulate that quantum computers may outperform classical computers on machine learning tasks. The field of quantum machine learning explores how to devise and implement quantum software that could enable machine learning that is faster than that of classical computers. Recent work has produced quantum algorithms that could act as the building blocks of machine learning programs, but the hardware and software challenges are still considerable.

  7. Quantum machine learning.

    PubMed

    Biamonte, Jacob; Wittek, Peter; Pancotti, Nicola; Rebentrost, Patrick; Wiebe, Nathan; Lloyd, Seth

    2017-09-13

    Fuelled by increasing computer power and algorithmic advances, machine learning techniques have become powerful tools for finding patterns in data. Quantum systems produce atypical patterns that classical systems are thought not to produce efficiently, so it is reasonable to postulate that quantum computers may outperform classical computers on machine learning tasks. The field of quantum machine learning explores how to devise and implement quantum software that could enable machine learning that is faster than that of classical computers. Recent work has produced quantum algorithms that could act as the building blocks of machine learning programs, but the hardware and software challenges are still considerable.

  8. Clamping in Boltzmann machines.

    PubMed

    Livesey, M

    1991-01-01

    A certain assumption that appears in the proof of correctness of the standard Boltzmann machine learning procedure is investigated. The assumption, called the clamping assumption, concerns the behavior of a Boltzmann machine when some of its units are clamped to a fixed state. It is argued that the clamping assumption is essentially an assertion of the time reversibility of a certain Markov chain underlying the behavior of the Boltzmann machine. As such, the clamping assumption is generally false, though it is certainly true of the Boltzmann machines themselves. The author also considers how the concept of the Boltzmann machine may be generalized while retaining the validity of the clamping assumption.

  9. Perspex machine: VII. The universal perspex machine

    NASA Astrophysics Data System (ADS)

    Anderson, James A. D. W.

    2006-01-01

    The perspex machine arose from the unification of projective geometry with the Turing machine. It uses a total arithmetic, called transreal arithmetic, that contains real arithmetic and allows division by zero. Transreal arithmetic is redefined here. The new arithmetic has both a positive and a negative infinity which lie at the extremes of the number line, and a number nullity that lies off the number line. We prove that nullity, 0/0, is a number. Hence a number may have one of four signs: negative, zero, positive, or nullity. It is, therefore, impossible to encode the sign of a number in one bit, as floating-point arithmetic attempts to do, resulting in the difficulty of having both positive and negative zeros and NaNs. Transrational arithmetic is consistent with Cantor arithmetic. In an extension to real arithmetic, the product of zero, an infinity, or nullity with its reciprocal is nullity, not unity. This avoids the usual contradictions that follow from allowing division by zero. Transreal arithmetic has a fixed algebraic structure and does not admit options as IEEE, floating-point arithmetic does. Most significantly, nullity has a simple semantics that is related to zero. Zero means "no value" and nullity means "no information." We argue that nullity is as useful to a manufactured computer as zero is to a human computer. The perspex machine is intended to offer one solution to the mind-body problem by showing how the computable aspects of mind and, perhaps, the whole of mind relates to the geometrical aspects of body and, perhaps, the whole of body. We review some of Turing's writings and show that he held the view that his machine has spatial properties. In particular, that it has the property of being a 7D lattice of compact spaces. Thus, we read Turing as believing that his machine relates computation to geometrical bodies. We simplify the perspex machine by substituting an augmented Euclidean geometry for projective geometry. This leads to a general

  10. Prediction and identification of the magnetic field close to electric machines

    NASA Astrophysics Data System (ADS)

    Papadopoulos, Peter J.; Ioannides, Maria G.

    1999-04-01

    The magnetic field around an electric machine operating at full load is predicted numerically and identified experimentally. A precise model of a three-phase induction machine is constructed considering the machine geometry, the windings and the stator and rotor materials. The field distribution close to the machine is determined using the discrete element technique, and actual measurements are carried out for identification purposes. An approximate human model is constructed and the magnetic field inside the human body is computed for a distance of 1 and 5 m from the machine. The magnetic field density is determined at specific points, and the induced current densities are computed.

  11. Four quadrant control of induction motors

    NASA Technical Reports Server (NTRS)

    Hansen, Irving G.

    1991-01-01

    Induction motors are the nation's workhorse, being the motor of choice in most applications due to their simple rugged construction. It has been estimated that 14 to 27 percent of the country's total electricity use could be saved with adjustable speed drives. Until now, induction motors have not been suited well for variable speed or servo-drives, due to the inherent complexity, size, and inefficiency of their variable speed controls. Work at NASA Lewis Research Center on field oriented control of induction motors using pulse population modulation method holds the promise for the desired drive electronics. The system allows for a variable voltage to frequency ratio which enables the user to operate the motor at maximum efficiency, while having independent control of both the speed and torque of an induction motor in all four quadrants of the speed torque map. Multiple horsepower machine drives were demonstrated, and work is on-going to develop a 20 hp average, 40 hp peak class of machine. The pulse population technique, results to date, and projections for implementation of this existing new motor control technology are discussed.

  12. Four quadrant control of induction motors

    NASA Astrophysics Data System (ADS)

    Hansen, Irving G.

    1991-03-01

    Induction motors are the nation's workhorse, being the motor of choice in most applications due to their simple rugged construction. It has been estimated that 14 to 27 percent of the country's total electricity use could be saved with adjustable speed drives. Until now, induction motors have not been suited well for variable speed or servo-drives, due to the inherent complexity, size, and inefficiency of their variable speed controls. Work at NASA Lewis Research Center on field oriented control of induction motors using pulse population modulation method holds the promise for the desired drive electronics. The system allows for a variable voltage to frequency ratio which enables the user to operate the motor at maximum efficiency, while having independent control of both the speed and torque of an induction motor in all four quadrants of the speed torque map. Multiple horsepower machine drives were demonstrated, and work is on-going to develop a 20 hp average, 40 hp peak class of machine. The pulse population technique, results to date, and projections for implementation of this existing new motor control technology are discussed.

  13. Fault Tolerant State Machines

    NASA Technical Reports Server (NTRS)

    Burke, Gary R.; Taft, Stephanie

    2004-01-01

    State machines are commonly used to control sequential logic in FPGAs and ASKS. An errant state machine can cause considerable damage to the device it is controlling. For example in space applications, the FPGA might be controlling Pyros, which when fired at the wrong time will cause a mission failure. Even a well designed state machine can be subject to random errors us a result of SEUs from the radiation environment in space. There are various ways to encode the states of a state machine, and the type of encoding makes a large difference in the susceptibility of the state machine to radiation. In this paper we compare 4 methods of state machine encoding and find which method gives the best fault tolerance, as well as determining the resources needed for each method.

  14. Machine tool locator

    DOEpatents

    Hanlon, John A.; Gill, Timothy J.

    2001-01-01

    Machine tools can be accurately measured and positioned on manufacturing machines within very small tolerances by use of an autocollimator on a 3-axis mount on a manufacturing machine and positioned so as to focus on a reference tooling ball or a machine tool, a digital camera connected to the viewing end of the autocollimator, and a marker and measure generator for receiving digital images from the camera, then displaying or measuring distances between the projection reticle and the reference reticle on the monitoring screen, and relating the distances to the actual position of the autocollimator relative to the reference tooling ball. The images and measurements are used to set the position of the machine tool and to measure the size and shape of the machine tool tip, and examine cutting edge wear. patent

  15. Multipolarity remanences in lower oceanic crustal gabbros recovered by drilling at Hess Deep (Integrated Ocean Drilling Program Expedition 345)

    NASA Astrophysics Data System (ADS)

    Morris, Antony; Horst, Andrew; Friedman, Sarah; Nozaka, Toshio

    2015-04-01

    A long-term goal of the scientific ocean drilling community is to understand the processes by which the ocean crust is constructed through magmatism, deformation, metamorphism and hydrothermal cooling. Insights into the magnetic properties of the lower crust have come from drilling at oceanic core complexes and in tectonic windows. At the Hess Deep Rift, propagation of the Cocos-Nazca Ridge into young, fast-spreading East Pacific Rise crust exposes a dismembered, but nearly complete lower crustal section. Here, IODP Expedition 345 (Site U1415) recovered primitive plutonic lithologies including gabbro, troctolitic gabbro and olivine gabbronorite. These rocks exhibit cumulate textures similar to those found in layered basic intrusions and some ophiolite complexes. Metamorphism is dominated by background greenschist facies alteration associated with cataclastic deformation that likely results from Cocos-Nazca rifting. Some intervals display complex, multiple remanence components within individual samples. A high temperature component unblocks above 500°-520°C and an intermediate temperature component of nearly antipodal direction unblocks between 425°-450°C and 500°-520°C. In addition, a few samples display a third component that unblocks between 100-350°C that is nearly parallel to the highest temperature component. These multiple, nearly antipodal components suggest that remanence was acquired in different geomagnetic chrons, and represent the first multipolarity remanences seen in Pacific lower oceanic crust. Similar remanence structures, however, have been reported in lower crustal gabbros recovered from slow-spreading rate crust along the Mid-Atlantic Ridge, and have been interpreted to reflect protracted accretion or protracted cooling. In contrast, at Hess Deep unblocking temperatures appear consistent with temperatures inferred for successive phases of alteration, suggesting an alteration history spanning at least two polarity chrons.

  16. Multipolarity Remanences in Lower Oceanic Crustal Gabbros Recovered By Drilling at Hess Deep (Integrated Ocean Drilling Program Expedition 345)

    NASA Astrophysics Data System (ADS)

    Morris, A.; Horst, A. J.; Friedman, S. A.

    2014-12-01

    A long-term goal of the scientific ocean drilling community is to understand the processes by which the ocean crust is constructed through magmatism, deformation, metamorphism and hydrothermal cooling. Insights into the magnetic properties of the lower crust have come from drilling at oceanic core complexes and in tectonic windows. At the Hess Deep Rift, propagation of the Cocos-Nazca Ridge into young, fast-spreading East Pacific Rise crust exposes a dismembered, but nearly complete lower crustal section. Here, IODP Expedition 345 (Site U1415) recovered primitive plutonic lithologies including gabbro, troctolitic gabbro and olivine gabbronorite. These rocks exhibit cumulate textures similar to those found in layered basic intrusions and some ophiolite complexes. Metamorphism is dominated by background greenschist facies alteration associated with cataclastic deformation that likely results from Cocos-Nazca rifting. Some intervals display complex, multiple remanence components within individual samples. A high temperature component unblocks above 500°-520°C and an intermediate temperature component of nearly antipodal direction unblocks between 425°-450°C and 500°-520°C. In addition, a few samples display a third component that unblocks between 100-350°C that is nearly parallel to the highest temperature component. These multiple, nearly antipodal components suggest that remanence was acquired in different geomagnetic chrons, and represent the first multipolarity remanences seen in Pacific lower oceanic crust. Similar remanence structures, however, have been reported in lower crustal gabbros recovered from slow-spreading rate crust along the Mid-Atlantic Ridge, and have been interpreted to reflect protracted accretion or protracted cooling. In contrast, at Hess Deep unblocking temperatures appear consistent with temperatures inferred for successive phases of alteration, suggesting an alteration history spanning at least two polarity chrons.

  17. Chaotic Boltzmann machines

    PubMed Central

    Suzuki, Hideyuki; Imura, Jun-ichi; Horio, Yoshihiko; Aihara, Kazuyuki

    2013-01-01

    The chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented. PMID:23558425

  18. Perspex machine II: visualization

    NASA Astrophysics Data System (ADS)

    Anderson, James A. D. W.

    2004-12-01

    We review the perspex machine and improve it by reducing its halting conditions to one condition. We also introduce a data structure, called the "access column," that can accelerate a wide class of perspex programs. We show how the perspex can be visualised as a tetrahedron, artificial neuron, computer program, and as a geometrical transformation. We discuss the temporal properties of the perspex machine, dissolve the famous time travel paradox, and present a hypothetical time machine. Finally, we discuss some mental properties and show how the perspex machine solves the mind-body problem and, specifically, how it provides one physical explanation for the occurrence of paradigm shifts.

  19. Perspex machine II: visualization

    NASA Astrophysics Data System (ADS)

    Anderson, James A. D. W.

    2005-01-01

    We review the perspex machine and improve it by reducing its halting conditions to one condition. We also introduce a data structure, called the "access column," that can accelerate a wide class of perspex programs. We show how the perspex can be visualised as a tetrahedron, artificial neuron, computer program, and as a geometrical transformation. We discuss the temporal properties of the perspex machine, dissolve the famous time travel paradox, and present a hypothetical time machine. Finally, we discuss some mental properties and show how the perspex machine solves the mind-body problem and, specifically, how it provides one physical explanation for the occurrence of paradigm shifts.

  20. Machine listening intelligence

    NASA Astrophysics Data System (ADS)

    Cella, C. E.

    2017-05-01

    This manifesto paper will introduce machine listening intelligence, an integrated research framework for acoustic and musical signals modelling, based on signal processing, deep learning and computational musicology.

  1. Progress in machine consciousness.

    PubMed

    Gamez, David

    2008-09-01

    This paper is a review of the work that has been carried out on machine consciousness. A clear overview of this diverse field is achieved by breaking machine consciousness down into four different areas, which are used to understand its aims, discuss its relationship with other subjects and outline the work that has been carried out so far. The criticisms that have been made against machine consciousness are also covered, along with its potential benefits, and the work that has been done on analysing systems for signs of consciousness. Some of the social and ethical issues raised by machine consciousness are examined at the end of the paper.

  2. Chaotic Boltzmann machines

    NASA Astrophysics Data System (ADS)

    Suzuki, Hideyuki; Imura, Jun-Ichi; Horio, Yoshihiko; Aihara, Kazuyuki

    2013-04-01

    The chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented.

  3. Chaotic Boltzmann machines.

    PubMed

    Suzuki, Hideyuki; Imura, Jun-ichi; Horio, Yoshihiko; Aihara, Kazuyuki

    2013-01-01

    The chaotic Boltzmann machine proposed in this paper is a chaotic pseudo-billiard system that works as a Boltzmann machine. Chaotic Boltzmann machines are shown numerically to have computing abilities comparable to conventional (stochastic) Boltzmann machines. Since no randomness is required, efficient hardware implementation is expected. Moreover, the ferromagnetic phase transition of the Ising model is shown to be characterised by the largest Lyapunov exponent of the proposed system. In general, a method to relate probabilistic models to nonlinear dynamics by derandomising Gibbs sampling is presented.

  4. Modernization of machines laboratory

    SciTech Connect

    Mako, T.J.; Kasten, D.; Kent, J.C.; Turner, S.C. )

    1992-01-01

    The Ohio State University has maintained an undergraduate machinery laboratory using 10 to 15 hp AC and DC machines. a recent gift from the American Electric Power Service Corporation is being used to modernize the laboratory. This modernization includes the electrical and mechanical refurbishment of the 10 to 15 hp machines, the development of a computerized data acquisition system, and the specification and purchase of a three-machine (1 to 2 hp) table-top unit with variable speed drives. This paper will present information about the computerized data acquisition system and how it is being used by the students to investigate machine characteristics.

  5. Short Circuit Analysis of Induction Machines Wind Power Application

    SciTech Connect

    Starke, Michael R; Smith, Travis M; Howard, Dustin; Harley, Ronald

    2012-01-01

    he short circuit behavior of Type I (fixed speed) wind turbine-generators is analyzed in this paper to aid in the protection coordination of wind plants of this type. A simple network consisting of one wind turbine-generator is analyzed for two network faults: a three phase short circuit and a phase A to ground fault. Electromagnetic transient simulations and sequence network calculations are compared for the two fault scenarios. It is found that traditional sequence network calculations give accurate results for the short circuit currents in the balanced fault case, but are inaccurate for the un-faulted phases in the unbalanced fault case. The time-current behavior of the fundamental frequency component of the short circuit currents for both fault cases are described, and found to differ significantly in the unbalanced and balanced fault cases

  6. Multipolar radiofrequency ablation using internally cooled electrodes in ex vivo bovine liver: correlation between volume of coagulation and amount of applied energy.

    PubMed

    Clasen, Stephan; Rempp, Hansjörg; Schmidt, Diethard; Schraml, Christina; Hoffmann, Rüdiger; Claussen, Claus D; Pereira, Philippe L

    2012-01-01

    To evaluate the relationship between applied energy and volume of coagulation induced by multipolar radiofrequency (RF) ablation. Multipolar RF ablations (n=80) were performed in ex vivo bovine liver. Three bipolar applicators with two electrodes located on each applicator shaft were placed in a triangular array. The power-output (75-225 W) and the distance between the different applicators (2, 3, 4, 5 cm) were systematically varied. The volume of confluent white coagulation and the amount of applied energy were assessed. Based on our experimental data the relationship between the volume of coagulation and applied energy was assessed by nonlinear regression analysis. The variability explained by the model was determined by the parameter r(2). The volume of coagulation increases with higher amounts of applied energy. The maximum amount of energy was applied at a power-output of 75 W and an applicator distance of 5 cm. The corresponding maximum volume of coagulation was 324 cm(3) and required an application of 453 kJ. The relationship between amount of applied energy (E) and volume (V) of coagulation can be described by the function, V=4.39E(0.7) (r(2)=0.88). By approximation the volume of coagulation can be calculated by the linear function V=0.61E+40.7 (r(2)=0.87). Ex vivo the relationship between volume of coagulation and amount of applied energy can be described by mathematical modeling. The amount of applied energy correlates to the volume of coagulation and may be a useful parameter to monitor multipolar RF ablation. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

  7. Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex.

    PubMed

    Ohshima, Toshio; Hirasawa, Motoyuki; Tabata, Hidenori; Mutoh, Tetsuji; Adachi, Tomoko; Suzuki, Hiromi; Saruta, Keiko; Iwasato, Takuji; Itohara, Shigeyoshi; Hashimoto, Mistuhiro; Nakajima, Kazunori; Ogawa, Masaharu; Kulkarni, Ashok B; Mikoshiba, Katsuhiko

    2007-06-01

    The mammalian cerebral cortex consists of six layers that are generated via coordinated neuronal migration during the embryonic period. Recent studies identified specific phases of radial migration of cortical neurons. After the final division, neurons transform from a multipolar to a bipolar shape within the subventricular zone-intermediate zone (SVZ-IZ) and then migrate along radial glial fibres. Mice lacking Cdk5 exhibit abnormal corticogenesis owing to neuronal migration defects. When we introduced GFP into migrating neurons at E14.5 by in utero electroporation, we observed migrating neurons in wild-type but not in Cdk5(-/-) embryos after 3-4 days. Introduction of the dominant-negative form of Cdk5 into the wild-type migrating neurons confirmed specific impairment of the multipolar-to-bipolar transition within the SVZ-IZ in a cell-autonomous manner. Cortex-specific Cdk5 conditional knockout mice showed inverted layering of the cerebral cortex and the layer V and callosal neurons, but not layer VI neurons, had severely impaired dendritic morphology. The amount of the dendritic protein Map2 was decreased in the cerebral cortex of Cdk5-deficient mice, and the axonal trajectory of cortical neurons within the cortex was also abnormal. These results indicate that Cdk5 is required for proper multipolar-to-bipolar transition, and a deficiency of Cdk5 results in abnormal morphology of pyramidal neurons. In addition, proper radial neuronal migration generates an inside-out pattern of cerebral cortex formation and normal axonal trajectories of cortical pyramidal neurons.

  8. Method and device for determining bond separation strength using induction heating

    NASA Technical Reports Server (NTRS)

    Coultrip, Robert H. (Inventor); Johnson, Samuel D. (Inventor); Copeland, Carl E. (Inventor); Phillips, W. Morris (Inventor); Fox, Robert L. (Inventor)

    1994-01-01

    An induction heating device includes an induction heating gun which includes a housing, a U-shaped pole piece having two spaced apart opposite ends defining a gap there between, the U-shaped pole piece being mounted in one end of the housing, and a tank circuit including an induction coil wrapped around the pole piece and a capacitor connected to the induction coil. A power source is connected to the tank circuit. A pull test machine is provided having a stationary chuck and a movable chuck, the two chucks holding two test pieces bonded together at a bond region. The heating gun is mounted on the pull test machine in close proximity to the bond region of the two test pieces, whereby when the tank circuit is energized, the two test pieces are heated by induction heating while a tension load is applied to the two test pieces by the pull test machine to determine separation strength of the bond region.

  9. Electromagnetic induction methods

    USDA-ARS?s Scientific Manuscript database

    Electromagnetic induction geophysical methods are finding greater and greater use for agricultural purposes. Electromagnetic induction methods measure the electrical conductivity (or resistivity) for a bulk volume of soil directly beneath the surface. An instrument called a ground conductivity meter...

  10. Drum cutter mining machine

    SciTech Connect

    Oberste-beulmann, K.; Schupphaus, H.

    1980-02-19

    A drum cutter mining machine includes a machine frame with a winch having a drive wheel to engage a rack or chain which extends along the path of travel by the mining machine to propel the machine along a mine face. The mining machine is made up of discrete units which include a machine body and machine housings joined to opposite sides of the machine body. The winch is either coupled through a drive train with a feed drive motor or coupled to the drive motor for cutter drums. The machine housings each support a pivot shaft coupled by an arm to a drum cutter. One of these housings includes a removable end cover and a recess adapted to receive a support housing for a spur gear system used to transmit torque from a feed drive motor to a reduction gear system which is, in turn, coupled to the drive wheel of the winch. In one embodiment, a removable end cover on the machine housing provides access to the feed drive motor. The feed drive motor is arranged so that the rotational axis of its drive output shaft extends transversely to the stow side of the machine frame. In another embodiment, the reduction gear system is arranged at one side of the pivot shaft for the cutter drum while the drive motor therefor is arranged at the other side of the pivot shaft and coupled thereto through the spur gear system. In a further embodiment, the reduction gear system is disposed between the feed motor and the pivot shaft.

  11. Diamond machine tool face lapping machine

    DOEpatents

    Yetter, H.H.

    1985-05-06

    An apparatus for shaping, sharpening and polishing diamond-tipped single-point machine tools. The isolation of a rotating grinding wheel from its driving apparatus using an air bearing and causing the tool to be shaped, polished or sharpened to be moved across the surface of the grinding wheel so that it does not remain at one radius for more than a single rotation of the grinding wheel has been found to readily result in machine tools of a quality which can only be obtained by the most tedious and costly processing procedures, and previously unattainable by simple lapping techniques.

  12. Machine learning of fault characteristics from rocket engine simulation data

    NASA Technical Reports Server (NTRS)

    Ke, Min; Ali, Moonis

    1990-01-01

    Transformation of data into knowledge through conceptual induction has been the focus of our research described in this paper. We have developed a Machine Learning System (MLS) to analyze the rocket engine simulation data. MLS can provide to its users fault analysis, characteristics, and conceptual descriptions of faults, and the relationships of attributes and sensors. All the results are critically important in identifying faults.

  13. Establishment of M1 multipolarity of a 6.5 (micro)2n resonance in 172Yb at E(gamma) = 3.3 MeV

    SciTech Connect

    Schiller, A; Voinov, A; Algin, E; Becker, J A; Bernstein, L A; Garrett, P E; Guttormsen, M; Nelson, R O; Rekstad, J; Siem, S

    2004-02-04

    Two-step-cascade spectra in {sup 172}Yb have been measured after thermal neutron capture. they are compared to calculations based on experimental values of the level density and radiative strength function (RSF) obtained from the {sup 173}Yb(3{sup 3}He,{alpha}{gamma}){sup 172}Yb reaction. The multipolarity of a 6.5(15) {mu}{sub N}{sup 2} resonance at E{sub {gamma}} = 3.3(1) MeV in the RSF is determined to be M1 by this comparison.

  14. 5-(3,4-Dimethoxybenzyl)-7-isopropyl-1,3,5-triazepane-2,6-dione acetonitrile solvate refined using a multipolar atom model.

    PubMed

    Ejsmont, Krzysztof; Boeglin, Joel; Didierjean, Claude; Guichard, Gilles; Jelsch, Christian

    2010-06-01

    The crystal structure of the title compound, C(16)H(23)N(3)O(4).CH(3)CN, was refined using a multipolar atom model transferred from an experimental electron-density database. The refinement showed some improvement in crystallographic statistical indices compared with the independent atom model. The triazepane ring adopts a twist-boat conformation. In the crystal structure, the molecule forms intermolecular contacts with 14 different neighbours. There are two N-H...O and one C-H...O intermolecular hydrogen bond.

  15. Multipolarity analysis for {sup 14}C high-energy resonance populated by ({sup 18}O,{sup 16}O) two-neutron transfer reaction

    SciTech Connect

    Carbone, D. Cavallaro, M.; Bondì, M.; Agodi, C.; Cunsolo, A.; Cappuzzello, F.; Azaiez, F.; Franchoo, S.; Khan, E.; Bonaccorso, A.; Fortunato, L.; Foti, A.; Linares, R.; Lubian, J.; Scarpaci, J. A.; Vitturi, A.

    2015-10-15

    The {sup 12}C({sup 18}O,{sup 16}O){sup 14}C reaction at 84 MeV incident energy has been explored up to high excitation energy of the residual nucleus thanks to the use of the MAGNEX spectrometer to detect the ejectiles. In the region above the two-neutron separation energy, a resonance has been observed at 16.9 MeV. A multipolarity analysis of the cross section angular distribution indicates an L = 0 character for such a transition.

  16. Teaching Arrangement Inductively.

    ERIC Educational Resources Information Center

    Mendelson, Michael

    1988-01-01

    Argues that teaching arrangement inductively offers an alternative to the standard imitation of business communication text models. Asserts that the inductive method stimulates individual rather than formulaic responses to the problems of organization, and that inductively-trained writers see arrangements as a powerful element in persuasive…

  17. Inductive Reasoning and Writing

    ERIC Educational Resources Information Center

    Rooks, Clay; Boyd, Robert

    2003-01-01

    Induction, properly understood, is not merely a game, nor is it a gimmick, nor is it an artificial way of explaining an element of reasoning. Proper understanding of inductive reasoning--and the various types of reasoning that the authors term inductive--enables the student to evaluate critically other people's writing and enhances the composition…

  18. Induction into Learning Communities

    ERIC Educational Resources Information Center

    Fulton, Kathleen; Yoon, Irene; Lee, Christine

    2005-01-01

    This paper presents the National Commission on Teaching and America's Future (NCTAF) vision for new teacher induction into strong schools that support a career of continuous professional growth. The paper examines data on induction's impact on teacher retention and emerging information on induction's effects on improving student learning, and goes…

  19. BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE MAKES BOTH MOLD HALVES INDIVIDUALLY WHICH ARE LATER ROTATED, ASSEMBLED, AND LOWERED TO POURING CONVEYORS BY ASSISTING MACHINES. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

  20. BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BRITISH MOLDING MACHINE, PBQ AUTOMATIC COPE AND DRAG MOLDING MACHINE MAKES BOTH MOLD HALVES INDIVIDUALLY WHICH ARE LATER ROTATED, ASSEMBLED, AND LOWERED TO POURING CONVEYORS BY ASSISTING MACHINES. - Southern Ductile Casting Company, Casting, 2217 Carolina Avenue, Bessemer, Jefferson County, AL

  1. 14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to north (90mm lens). - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  2. THE TEACHING MACHINE.

    ERIC Educational Resources Information Center

    KLEIN, CHARLES; WAYNE, ELLIS

    THE ROLE OF THE TEACHING MACHINE IS COMPARED WITH THE ROLE OF THE PROGRAMED TEXTBOOK. THE TEACHING MACHINE IS USED FOR INDIVIDUAL INSTRUCTION, CONTAINS AND PRESENTS PROGRAM CONTENT IN STEPS, PROVIDES A MEANS WHEREBY THE STUDENT MAY RESPOND TO THE PROGRAM, PROVIDES THE STUDENT WITH IMMEDIATE INFORMATION OF SOME KIND CONCERNING HIS RESPONSE THAT CAN…

  3. Simple Machines Made Simple.

    ERIC Educational Resources Information Center

    St. Andre, Ralph E.

    Simple machines have become a lost point of study in elementary schools as teachers continue to have more material to cover. This manual provides hands-on, cooperative learning activities for grades three through eight concerning the six simple machines: wheel and axle, inclined plane, screw, pulley, wedge, and lever. Most activities can be…

  4. Machining heavy plastic sections

    NASA Technical Reports Server (NTRS)

    Stalkup, O. M.

    1967-01-01

    Machining technique produces consistently satisfactory plane-parallel optical surfaces for pressure windows, made of plexiglass, required to support a photographic study of liquid rocket combustion processes. The surfaces are machined and polished to the required tolerances and show no degradation from stress relaxation over periods as long as 6 months.

  5. Technique for Machining Glass

    NASA Technical Reports Server (NTRS)

    Rice, S. H.

    1982-01-01

    Process for machining glass with conventional carbide tools requires a small quantity of a lubricant for aluminum applied to area of glass to be machined. A carbide tool is then placed against workpiece with light pressure. Tool is raised periodically to clear work of glass dust and particles. Additional lubricant is applied as it is displaced.

  6. Simple Machine Junk Cars

    ERIC Educational Resources Information Center

    Herald, Christine

    2010-01-01

    During the month of May, the author's eighth-grade physical science students study the six simple machines through hands-on activities, reading assignments, videos, and notes. At the end of the month, they can easily identify the six types of simple machine: inclined plane, wheel and axle, pulley, screw, wedge, and lever. To conclude this unit,…

  7. Human Machine Learning Symbiosis

    ERIC Educational Resources Information Center

    Walsh, Kenneth R.; Hoque, Md Tamjidul; Williams, Kim H.

    2017-01-01

    Human Machine Learning Symbiosis is a cooperative system where both the human learner and the machine learner learn from each other to create an effective and efficient learning environment adapted to the needs of the human learner. Such a system can be used in online learning modules so that the modules adapt to each learner's learning state both…

  8. Simple Machines Made Simple.

    ERIC Educational Resources Information Center

    St. Andre, Ralph E.

    Simple machines have become a lost point of study in elementary schools as teachers continue to have more material to cover. This manual provides hands-on, cooperative learning activities for grades three through eight concerning the six simple machines: wheel and axle, inclined plane, screw, pulley, wedge, and lever. Most activities can be…

  9. Machine Translation Project

    NASA Technical Reports Server (NTRS)

    Bajis, Katie

    1993-01-01

    The characteristics and capabilities of existing machine translation systems were examined and procurement recommendations were developed. Four systems, SYSTRAN, GLOBALINK, PC TRANSLATOR, and STYLUS, were determined to meet the NASA requirements for a machine translation system. Initially, four language pairs were selected for implementation. These are Russian-English, French-English, German-English, and Japanese-English.

  10. Compound taper milling machine

    NASA Technical Reports Server (NTRS)

    Campbell, N. R.

    1969-01-01

    Simple, inexpensive milling machine tapers panels from a common apex to a uniform height at panel edge regardless of the panel perimeter configuration. The machine consists of an adjustable angled beam upon which the milling tool moves back and forth above a rotatable table upon which the workpiece is held.

  11. The Hooey Machine.

    ERIC Educational Resources Information Center

    Scarnati, James T.; Tice, Craig J.

    1992-01-01

    Describes how students can make and use Hooey Machines to learn how mechanical energy can be transferred from one object to another within a system. The Hooey Machine is made using a pencil, eight thumbtacks, one pushpin, tape, scissors, graph paper, and a plastic lid. (PR)

  12. Semantics via Machine Translation

    ERIC Educational Resources Information Center

    Culhane, P. T.

    1977-01-01

    Recent experiments in machine translation have given the semantic elements of collocation in Russian more objective criteria. Soviet linguists in search of semantic relationships have attempted to devise a semantic synthesis for construction of a basic language for machine translation. One such effort is summarized. (CHK)

  13. Stirling machine operating experience

    SciTech Connect

    Ross, B.; Dudenhoefer, J.E.

    1994-09-01

    Numerous Stirling machines have been built and operated, but the operating experience of these machines is not well known. It is important to examine this operating experience in detail, because it largely substantiates the claim that stirling machines are capable of reliable and lengthy operating lives. The amount of data that exists is impressive, considering that many of the machines that have been built are developmental machines intended to show proof of concept, and are not expected to operate for lengthy periods of time. Some Stirling machines (typically free-piston machines) achieve long life through non-contact bearings, while other Stirling machines (typically kinematic) have achieved long operating lives through regular seal and bearing replacements. In addition to engine and system testing, life testing of critical components is also considered. The record in this paper is not complete, due to the reluctance of some organizations to release operational data and because several organizations were not contacted. The authors intend to repeat this assessment in three years, hoping for even greater participation.

  14. An asymptotical machine

    NASA Astrophysics Data System (ADS)

    Cristallini, Achille

    2016-07-01

    A new and intriguing machine may be obtained replacing the moving pulley of a gun tackle with a fixed point in the rope. Its most important feature is the asymptotic efficiency. Here we obtain a satisfactory description of this machine by means of vector calculus and elementary trigonometry. The mathematical model has been compared with experimental data and briefly discussed.

  15. Biological Molecular Machines

    NASA Astrophysics Data System (ADS)

    Kurzyński, Michał

    2007-11-01

    Like small molecules taking part in usual chemical reactions, biological molecular machines perform their functions owing to thermal fluctuations and the only difference consists in more complex and specially organized internal dynamics. It is this dynamics that determines processes of free energy transduction in molecular machines. The case of the actomyosin motor is considered in some detail.

  16. Machine Translation Project

    NASA Technical Reports Server (NTRS)

    Bajis, Katie

    1993-01-01

    The characteristics and capabilities of existing machine translation systems were examined and procurement recommendations were developed. Four systems, SYSTRAN, GLOBALINK, PC TRANSLATOR, and STYLUS, were determined to meet the NASA requirements for a machine translation system. Initially, four language pairs were selected for implementation. These are Russian-English, French-English, German-English, and Japanese-English.

  17. Technique for Machining Glass

    NASA Technical Reports Server (NTRS)

    Rice, S. H.

    1982-01-01

    Process for machining glass with conventional carbide tools requires a small quantity of a lubricant for aluminum applied to area of glass to be machined. A carbide tool is then placed against workpiece with light pressure. Tool is raised periodically to clear work of glass dust and particles. Additional lubricant is applied as it is displaced.

  18. Simple Machine Junk Cars

    ERIC Educational Resources Information Center

    Herald, Christine

    2010-01-01

    During the month of May, the author's eighth-grade physical science students study the six simple machines through hands-on activities, reading assignments, videos, and notes. At the end of the month, they can easily identify the six types of simple machine: inclined plane, wheel and axle, pulley, screw, wedge, and lever. To conclude this unit,…

  19. Micro-machining.

    PubMed

    Brinksmeier, Ekkard; Preuss, Werner

    2012-08-28

    Manipulating bulk material at the atomic level is considered to be the domain of physics, chemistry and nanotechnology. However, precision engineering, especially micro-machining, has become a powerful tool for controlling the surface properties and sub-surface integrity of the optical, electronic and mechanical functional parts in a regime where continuum mechanics is left behind and the quantum nature of matter comes into play. The surprising subtlety of micro-machining results from the extraordinary precision of tools, machines and controls expanding into the nanometre range-a hundred times more precise than the wavelength of light. In this paper, we will outline the development of precision engineering, highlight modern achievements of ultra-precision machining and discuss the necessity of a deeper physical understanding of micro-machining.

  20. Introduction to machine learning.

    PubMed

    Baştanlar, Yalin; Ozuysal, Mustafa

    2014-01-01

    The machine learning field, which can be briefly defined as enabling computers make successful predictions using past experiences, has exhibited an impressive development recently with the help of the rapid increase in the storage capacity and processing power of computers. Together with many other disciplines, machine learning methods have been widely employed in bioinformatics. The difficulties and cost of biological analyses have led to the development of sophisticated machine learning approaches for this application area. In this chapter, we first review the fundamental concepts of machine learning such as feature assessment, unsupervised versus supervised learning and types of classification. Then, we point out the main issues of designing machine learning experiments and their performance evaluation. Finally, we introduce some supervised learning methods.

  1. Machine tool evaluation and machining operation development

    SciTech Connect

    Morris, T.O.; Kegg, R.

    1997-03-15

    The purpose of this CRADA was to support Cincinnati Milacron`s needs in fabricating precision components, from difficult to machine materials, while maintaining and enhancing the precision manufacturing skills of the Oak Ridge Complex. Oak Ridge and Cincinnati Milacron personnel worked in a team relationship wherein each contributed equally to the success of the program. Process characterization, control technologies, machine tool capabilities, and environmental issues were the primary focus areas. In general, Oak Ridge contributed a wider range of expertise in machine tool testing and monitoring, and environmental testing on machining fluids to the defined tasks while Cincinnati Milacron personnel provided equipment, operations-specific knowledge and shop-floor services to each task. Cincinnati Milacron was very pleased with the results of all of the CRADA tasks. However, some of the environmental tasks were not carried through to a desired completion due to an expanding realization of need as the work progressed. This expansion of the desired goals then exceeded the time length of the CRADA. Discussions are underway on continuing these tasks under either a Work for Others agreement or some alternate funding.

  2. Pulsed IR inductive lasers

    NASA Astrophysics Data System (ADS)

    Razhev, A. M.; Churkin, D. S.; Kargapol'tsev, E. S.

    2014-07-01

    Pulsed inductive discharge is a new alternative method of pumping active gas laser media. The work presents results of experimental investigations of near, mid, and far IR inductive gas lasers (H2, HF, and CO2) operating at different transitions of atoms and molecules with different mechanisms of formation of inversion population. The excitation systems of a pulsed inductive cylindrical discharge (pulsed inductively coupled plasma) and pulsed RF inductive discharge in the gases are developed. Various gas mixtures including H2, N2, He, Ne, F2, NF3, and SF6 are used. Characteristics of near IR H2 laser radiation are investigated. Maximal pulse peak power of 7 kW is achieved. The possibility of using a pulsed inductive discharge as a new method of pumping HF laser active medium is demonstrated. The pulsed RF inductive CO2 laser is created and a total efficiency of 17% is achieved.

  3. Dissociation and serenity induction.

    PubMed

    Zoellner, Lori A; Sacks, Matthew B; Foa, Edna B

    2007-09-01

    Dissociation is a common experience during or immediately after a traumatic event; yet, most of the current knowledge regarding dissociation is retrospective in nature. The aim of the present study investigated a non-pharmacological method of dissociative induction with a clinical sample. Participants with PTSD and non-trauma exposed participants were randomly assigned to receive either a dissociative induction, or a serenity induction, based on modified Velten mood induction procedures. Participants receiving the dissociative induction reported higher state-dissociation than those receiving the serenity induction. The PTSD group reported greater state dissociation than the non-trauma exposed group, regardless of induction. State dissociation was related to trait dissociation, PTSD severity, and depression. The present results provide an initial demonstration of the viability for inducing state dissociation in the laboratory with a PTSD sample.

  4. General methodology to optimize damping functions to account for charge penetration effects in electrostatic calculations using multicentered multipolar expansions.

    PubMed

    Werneck, Araken S; Filho, Tarcísio M Rocha; Dardenne, Laurent E

    2008-01-17

    We developed a methodology to optimize exponential damping functions to account for charge penetration effects when computing molecular electrostatic properties using the multicentered multipolar expansion method (MME). This methodology is based in the optimization of a damping parameter set using a two-step fast local fitting procedure and the ab initio (Hartree-Fock/6-31G** and 6-31G**+) electrostatic potential calculated in a set of concentric grid of points as reference. The principal aspect of the methodology is a first local fitting step which generates a focused initial guess to improve the performance of a simplex method avoiding the use of multiple runs and the choice of initial guesses. Three different strategies for the determination of optimized damping parameters were tested in the following studies: (1) investigation of the error in the calculation of the electrostatic interaction energy for five hydrogen-bonded dimers at standard and nonstandard hydrogen-bonded geometries and at nonequilibrium geometries; (2) calculation of the electrostatic molecular properties (potential and electric field) for eight small molecular systems (methanol, ammonia, water, formamide, dichloromethane, acetone, dimethyl sulfoxide, and acetonitrile) and for the 20 amino acids. Our results show that the methodology performs well not only for small molecules but also for relatively larger molecular systems. The analysis of the distinct parameter sets associated with different optimization strategies show that (i) a specific parameter set is more suitable and more general for electrostatic interaction energy calculations, with an average absolute error of 0.46 kcal/mol at hydrogen-bond geometries; (ii) a second parameter set is more suitable for electrostatic potential and electric field calculations at and outside the van der Waals (vdW) envelope, with an average error decrease >72% at the vdW surface. A more general amino acid damping parameter set was constructed from the

  5. [Peculiarities of dopamine receptors on the membrane of spinal cord multipolar neurons of the brook lamprey Lampetra planeri].

    PubMed

    Bukinich, A a; Tsvetkov, E A; Veselkin, N P

    2007-01-01

    On isolated multiporal neurons of spinal cord of amniocoete larva of the brook lamprey Lampetra planeri, by the patch-clamp method in configuration "the whole cell", a modulating effect of dopamine on potential-activated Na+ currents was studied. Application of dopamine (10 microM) was shown to produce a complex action on the sodium current amplitude. In some cases a decrease of the amplitude, on average, by 13.5 +/- 2.2% was found, while in others--an increase, on average, by 8.6 +/- 6.1%. The modulation dopamine effect was not accompanied by any changes either of the threshold of the current appearance or of resistance of neuronal cell membranes. Pharmacological analysis with use of dopamine agonist has shown that the agonist of D1-receptors (-)-SKF-38393 (10 microM) decreases the Na+ current amplitude, whereas the agonist of D2-receptors (-)-quinpirole (10 microM) can produce in different cells both an increase, by 30.7 +/- 17.0 %, and a decrease, by 13.2 +/- 3.1%, of the Na+ current amplitude. The obtained data indicate the existence of D1- and D2-receptors on the membrane of multipolar spinal neurons of the amniocoete larva of the brook lamprey. Study of action of antagonists has shown that the antagonist of D1-receptors (+)-SCH-23390 (10 microM) does not affect action of the agonist of D1-receptors (-)-SKF-38393 (10 microM); the antagonist of D2-receptors (-)-sulpiride (10 microM) blocks completely effects both of the agonist of D1-receptors (-)-SKF-38393 (10 microM) and of the agonist of D2-receptors (-)-quinpirole (10 microM). The antagonist of D1-receptors (+)-SCH-23390 (10 microM) produced no effect on action of the agonist of D1-receptors (-)-SKF-38393 (10 microM). The obtained data indicate peculiarities of dopamine receptors of Cyclostomata as compared with those in mammals.

  6. Circle diagram approach for self excited induction generators

    SciTech Connect

    Muljadi, E.; Carlin, P.W.; Osgood, R.M.

    1993-05-01

    When an induction generator is connected to a utility line supply, the voltage and frequency at the terminal output are the same as the voltage and frequency of the utility line supply to which the generator is connected. The reactive power needed by the induction generator is supplied by the utility and the real power is returned to the utility. With a fixed frequency dictated by the utility, the induction machine starts generating above the synchronous speed. The range of speed is also limited by the slip. At a very high slip, the copper losses increases as the current increases. On the other hand, in an isolated operation, the induction generator operates in self-excitation mode. It determines its own voltage and frequency. These two quantities depend on the size of the AC capacitor, the induction machine parameters, the electrical load, and the speed of the generator. The operating speed of the induction generator is extended without generating excessive loss. This paper presents an analytical study by utilizing a circle diagram to illustrate the operation of the induction generator in isolated operation. The steady-state calculations are presented to support the analysis. Possible applications for the system in variable-speed generation are currently under investigation. The output can be directly connected to equipment that is non-sensitive to the frequency (a heater, battery charger, etc.) or can be connected to a converter to get a fixed-frequency AC output.

  7. Performance Analysis of Saturated Induction Motors by Virtual Tests

    ERIC Educational Resources Information Center

    Ojaghi, M.; Faiz, J.; Kazemi, M.; Rezaei, M.

    2012-01-01

    Many undergraduate-level electrical machines textbooks give detailed treatments of the performance of induction motors. Students can deepen this understanding of motor performance by performing the appropriate practical work in laboratories or in simulation using proper software packages. This paper considers various common and less-common tests…

  8. Performance Analysis of Saturated Induction Motors by Virtual Tests

    ERIC Educational Resources Information Center

    Ojaghi, M.; Faiz, J.; Kazemi, M.; Rezaei, M.

    2012-01-01

    Many undergraduate-level electrical machines textbooks give detailed treatments of the performance of induction motors. Students can deepen this understanding of motor performance by performing the appropriate practical work in laboratories or in simulation using proper software packages. This paper considers various common and less-common tests…

  9. Induction accelerators and free-electron lasers at LLNL: Beam Research Program

    SciTech Connect

    Briggs, R.J.

    1989-02-15

    Linear induction accelerators have been developed to produce pulses of charged particles at voltages exceeding the capabilities of single-stage, diode-type accelerators and at currents too high rf accelerators. In principle, one can accelerate charged particles to arbitrarily high voltages using a multistage induction machine. The advent of magnetic pulse power systems makes sustained operation at high repetition rates practical, and high-average-power capability is very likely to open up many new applications of induction machines. In Part A of this paper, we survey the US induction linac technology, emphasizing electron machines. We also give a simplified description of how induction machines couple energy to the electron beam to illustrate many general issues that designers of high-brightness and high-average-power induction linacs must consider. We give an example of the application of induction accelerator technology to the relativistic klystron, a power source for high-gradient accelerators. In Part B we address the application of LIAs to free-electron lasers. The multikiloampere peak currents available from linear induction accelerators make high-gain, free-electron laser amplifier configurations feasible. High extraction efficiencies in a single mass of the electron beam are possible if the wiggler parameters are appropriately ''tapered'', as recently demonstrated at millimeter wavelengths on the 4-MeV ELF facility. Key issues involved in extending the technology to shorter wavelengths and higher average powers are described. Current FEL experiments at LLNL are discussed. 5 refs., 16 figs.

  10. Multipolar, time-dynamical model for the loss compensation and lasing of a spherical plasmonic nanoparticle spaser immersed in an active gain medium

    PubMed Central

    Veltri, Alessandro; Chipouline, Arkadi; Aradian, Ashod

    2016-01-01

    The plasmonic response of a metal nanoparticle in the presence of surrounding gain elements is studied, using a space and time-dependent model, which integrates a quantum formalism to describe the gain and a classical treatment for the metal. Our model fully takes into account the influence of the system geometry (nanosphere) and offers for the first time, the possibility to describe the temporal evolution of the fields and the coupling among the multipolar modes of the particle. We calculate the lasing threshold value for all multipoles of the spaser, and demonstrate that the dipolar one is lowest. The onset of the lasing instability, in the linear regime, is then studied both with and without external field forcing. We also study the behaviour of the system below the lasing threshold, with the external field, demonstrating the existence of an amplification regime where the nanoparticle’s plasmon is strongly enhanced as the threshold is approached. Finally, a qualitative discussion is provided on later, non-linear stages of the dynamics and the approach to the steady-state of the spaser; in particular, it is shown that, for the considered geometry, the spasing is necessarily multi-modal and multipolar modes are always activated. PMID:27625072

  11. C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development.

    PubMed

    Shah, Bhavin; Lutter, Daniela; Bochenek, Magdalena L; Kato, Katsuhiro; Tsytsyura, Yaroslav; Glyvuk, Natalia; Sakakibara, Akira; Klingauf, Jürgen; Adams, Ralf H; Püschel, Andreas W

    2016-01-01

    The establishment of a polarized morphology is essential for the development and function of neurons. During the development of the mammalian neocortex, neurons arise in the ventricular zone (VZ) from radial glia cells (RGCs) and leave the VZ to generate the cortical plate (CP). During their migration, newborn neurons first assume a multipolar morphology in the subventricular zone (SVZ) and lower intermediate zone (IZ). Subsequently, they undergo a multi-to-bipolar (MTB) transition to become bipolar in the upper IZ by developing a leading process and a trailing axon. The small GTPases Rap1A and Rap1B act as master regulators of neural cell polarity in the developing mouse neocortex. They are required for maintaining the polarity of RGCs and directing the MTB transition of multipolar neurons. Here we show that the Rap1 guanine nucleotide exchange factor (GEF) C3G (encoded by the Rapgef1 gene) is a crucial regulator of the MTB transition in vivo by conditionally inactivating the Rapgef1 gene in the developing mouse cortex at different time points during neuronal development. Inactivation of C3G results in defects in neuronal migration, axon formation and cortical lamination. Live cell imaging shows that C3G is required in cortical neurons for both the specification of an axon and the initiation of radial migration by forming a leading process.

  12. Multipolar, time-dynamical model for the loss compensation and lasing of a spherical plasmonic nanoparticle spaser immersed in an active gain medium

    NASA Astrophysics Data System (ADS)

    Veltri, Alessandro; Chipouline, Arkadi; Aradian, Ashod

    2016-09-01

    The plasmonic response of a metal nanoparticle in the presence of surrounding gain elements is studied, using a space and time-dependent model, which integrates a quantum formalism to describe the gain and a classical treatment for the metal. Our model fully takes into account the influence of the system geometry (nanosphere) and offers for the first time, the possibility to describe the temporal evolution of the fields and the coupling among the multipolar modes of the particle. We calculate the lasing threshold value for all multipoles of the spaser, and demonstrate that the dipolar one is lowest. The onset of the lasing instability, in the linear regime, is then studied both with and without external field forcing. We also study the behaviour of the system below the lasing threshold, with the external field, demonstrating the existence of an amplification regime where the nanoparticle’s plasmon is strongly enhanced as the threshold is approached. Finally, a qualitative discussion is provided on later, non-linear stages of the dynamics and the approach to the steady-state of the spaser; in particular, it is shown that, for the considered geometry, the spasing is necessarily multi-modal and multipolar modes are always activated.

  13. Machine Learning and Radiology

    PubMed Central

    Wang, Shijun; Summers, Ronald M.

    2012-01-01

    In this paper, we give a short introduction to machine learning and survey its applications in radiology. We focused on six categories of applications in radiology: medical image segmentation, registration, computer aided detection and diagnosis, brain function or activity analysis and neurological disease diagnosis from fMR images, content-based image retrieval systems for CT or MRI images, and text analysis of radiology reports using natural language processing (NLP) and natural language understanding (NLU). This survey shows that machine learning plays a key role in many radiology applications. Machine learning identifies complex patterns automatically and helps radiologists make intelligent decisions on radiology data such as conventional radiographs, CT, MRI, and PET images and radiology reports. In many applications, the performance of machine learning-based automatic detection and diagnosis systems has shown to be comparable to that of a well-trained and experienced radiologist. Technology development in machine learning and radiology will benefit from each other in the long run. Key contributions and common characteristics of machine learning techniques in radiology are discussed. We also discuss the problem of translating machine learning applications to the radiology clinical setting, including advantages and potential barriers. PMID:22465077

  14. The Basic Anaesthesia Machine

    PubMed Central

    Gurudatt, CL

    2013-01-01

    After WTG Morton's first public demonstration in 1846 of use of ether as an anaesthetic agent, for many years anaesthesiologists did not require a machine to deliver anaesthesia to the patients. After the introduction of oxygen and nitrous oxide in the form of compressed gases in cylinders, there was a necessity for mounting these cylinders on a metal frame. This stimulated many people to attempt to construct the anaesthesia machine. HEG Boyle in the year 1917 modified the Gwathmey's machine and this became popular as Boyle anaesthesia machine. Though a lot of changes have been made for the original Boyle machine still the basic structure remains the same. All the subsequent changes which have been brought are mainly to improve the safety of the patients. Knowing the details of the basic machine will make the trainee to understand the additional improvements. It is also important for every practicing anaesthesiologist to have a thorough knowledge of the basic anaesthesia machine for safe conduct of anaesthesia. PMID:24249876

  15. The basic anaesthesia machine.

    PubMed

    Gurudatt, Cl

    2013-09-01

    After WTG Morton's first public demonstration in 1846 of use of ether as an anaesthetic agent, for many years anaesthesiologists did not require a machine to deliver anaesthesia to the patients. After the introduction of oxygen and nitrous oxide in the form of compressed gases in cylinders, there was a necessity for mounting these cylinders on a metal frame. This stimulated many people to attempt to construct the anaesthesia machine. HEG Boyle in the year 1917 modified the Gwathmey's machine and this became popular as Boyle anaesthesia machine. Though a lot of changes have been made for the original Boyle machine still the basic structure remains the same. All the subsequent changes which have been brought are mainly to improve the safety of the patients. Knowing the details of the basic machine will make the trainee to understand the additional improvements. It is also important for every practicing anaesthesiologist to have a thorough knowledge of the basic anaesthesia machine for safe conduct of anaesthesia.

  16. DNA-based machines.

    PubMed

    Wang, Fuan; Willner, Bilha; Willner, Itamar

    2014-01-01

    The base sequence in nucleic acids encodes substantial structural and functional information into the biopolymer. This encoded information provides the basis for the tailoring and assembly of DNA machines. A DNA machine is defined as a molecular device that exhibits the following fundamental features. (1) It performs a fuel-driven mechanical process that mimics macroscopic machines. (2) The mechanical process requires an energy input, "fuel." (3) The mechanical operation is accompanied by an energy consumption process that leads to "waste products." (4) The cyclic operation of the DNA devices, involves the use of "fuel" and "anti-fuel" ingredients. A variety of DNA-based machines are described, including the construction of "tweezers," "walkers," "robots," "cranes," "transporters," "springs," "gears," and interlocked cyclic DNA structures acting as reconfigurable catenanes, rotaxanes, and rotors. Different "fuels", such as nucleic acid strands, pH (H⁺/OH⁻), metal ions, and light, are used to trigger the mechanical functions of the DNA devices. The operation of the devices in solution and on surfaces is described, and a variety of optical, electrical, and photoelectrochemical methods to follow the operations of the DNA machines are presented. We further address the possible applications of DNA machines and the future perspectives of molecular DNA devices. These include the application of DNA machines as functional structures for the construction of logic gates and computing, for the programmed organization of metallic nanoparticle structures and the control of plasmonic properties, and for controlling chemical transformations by DNA machines. We further discuss the future applications of DNA machines for intracellular sensing, controlling intracellular metabolic pathways, and the use of the functional nanostructures for drug delivery and medical applications.

  17. Inferring Mealy Machines

    NASA Astrophysics Data System (ADS)

    Shahbaz, Muzammil; Groz, Roland

    Automata learning techniques are getting significant importance for their applications in a wide variety of software engineering problems, especially in the analysis and testing of complex systems. In recent studies, a previous learning approach [1] has been extended to synthesize Mealy machine models which are specifically tailored for I/O based systems. In this paper, we discuss the inference of Mealy machines and propose improvements that reduces the worst-time learning complexity of the existing algorithm. The gain over the complexity of the proposed algorithm has also been confirmed by experimentation on a large set of finite state machines.

  18. Machine Tool Software

    NASA Technical Reports Server (NTRS)

    1988-01-01

    A NASA-developed software package has played a part in technical education of students who major in Mechanical Engineering Technology at William Rainey Harper College. Professor Hack has been using (APT) Automatically Programmed Tool Software since 1969 in his CAD/CAM Computer Aided Design and Manufacturing curriculum. Professor Hack teaches the use of APT programming languages for control of metal cutting machines. Machine tool instructions are geometry definitions written in APT Language to constitute a "part program." The part program is processed by the machine tool. CAD/CAM students go from writing a program to cutting steel in the course of a semester.

  19. Quantum Boltzmann Machine

    NASA Astrophysics Data System (ADS)

    Kulchytskyy, Bohdan; Andriyash, Evgeny; Amin, Mohammed; Melko, Roger

    The field of machine learning has been revolutionized by the recent improvements in the training of deep networks. Their architecture is based on a set of stacked layers of simpler modules. One of the most successful building blocks, known as a restricted Boltzmann machine, is an energetic model based on the classical Ising Hamiltonian. In our work, we investigate the benefits of quantum effects on the learning capacity of Boltzmann machines by extending its underlying Hamiltonian with a transverse field. For this purpose, we employ exact and stochastic training procedures on data sets with physical origins.

  20. 16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Interior, Machine Shop, Roundhouse Machine Shop Extension, Southern Pacific Railroad Carlin Shops, view to south (90mm lens). Note the large segmental-arched doorway to move locomotives in and out of Machine Shop. - Southern Pacific Railroad, Carlin Shops, Roundhouse Machine Shop Extension, Foot of Sixth Street, Carlin, Elko County, NV

  1. Tunnel boring machine

    SciTech Connect

    Snyder, L. L.

    1985-07-09

    A tunnel boring machine for controlled boring of a curvilinear tunnel including a rotating cutter wheel mounted on the forward end of a thrust cylinder assembly having a central longitudinal axis aligned with the cutter wheel axis of rotation; the thrust cylinder assembly comprising a cylinder barrel and an extendable and retractable thrust arm received therein. An anchoring assembly is pivotally attached to the rear end of the cylinder barrel for anchoring the machine during a cutting stroke and providing a rear end pivot axis during curved cutting strokes. A pair of laterally extending, extendable and retractable arms are fixedly mounted at a forward portion of the cylinder barrel for providing lateral displacement in a laterally curved cutting mode and for anchoring the machine between cutting strokes and during straight line boring. Forward and rear transverse displacement and support assemblies are provided to facilitate cutting in a transversely curved cutting mode and to facilitate machine movement between cutting strokes.

  2. Molecular Machines: Nanoscale gadgets

    NASA Astrophysics Data System (ADS)

    Garcia-Garibay, Miguel A.

    2008-06-01

    Meeting their biological counterparts halfway, artificial molecular machines embedded in liquid crystals, crystalline solids and mesoporous materials are poised to meet the demands of the next generation of functional materials.

  3. Sequential inductive learning

    SciTech Connect

    Gratch, J.

    1996-12-31

    This article advocates a new model for inductive learning. Called sequential induction, it helps bridge classical fixed-sample learning techniques (which are efficient but difficult to formally characterize), and worst-case approaches (which provide strong statistical guarantees but are too inefficient for practical use). Learning proceeds as a sequence of decisions which are informed by training data. By analyzing induction at the level of these decisions, and by utilizing the only enough data to make each decision, sequential induction provides statistical guarantees but with substantially less data than worst-case methods require. The sequential inductive model is also useful as a method for determining a sufficient sample size for inductive learning and as such, is relevant to learning problems where the preponderance of data or the cost of gathering data precludes the use of traditional methods.

  4. Approaches to Machine Learning.

    DTIC Science & Technology

    1984-02-16

    The field of machine learning strives to develop methods and techniques to automatic the acquisition of new information, new skills, and new ways of organizing existing information. In this article, we review the major approaches to machine learning in symbolic domains, covering the tasks of learning concepts from examples, learning search methods, conceptual clustering, and language acquisition. We illustrate each of the basic approaches with paradigmatic examples. (Author)

  5. Sealing intersecting vane machines

    DOEpatents

    Martin, Jedd N.; Chomyszak, Stephen M.

    2005-06-07

    The invention provides a toroidal intersecting vane machine incorporating intersecting rotors to form primary and secondary chambers whose porting configurations minimize friction and maximize efficiency. Specifically, it is an object of the invention to provide a toroidal intersecting vane machine that greatly reduces the frictional losses through intersecting surfaces without the need for external gearing by modifying the width of one or both tracks at the point of intermeshing. The inventions described herein relate to these improvements.

  6. Sealing intersecting vane machines

    DOEpatents

    Martin, Jedd N.; Chomyszak, Stephen M.

    2007-06-05

    The invention provides a toroidal intersecting vane machine incorporating intersecting rotors to form primary and secondary chambers whose porting configurations minimize friction and maximize efficiency. Specifically, it is an object of the invention to provide a toroidal intersecting vane machine that greatly reduces the frictional losses through intersecting surfaces without the need for external gearing by modifying the width of one or both tracks at the point of intermeshing. The inventions described herein relate to these improvements.

  7. Maraging Steel Machining Improvements

    DTIC Science & Technology

    2007-04-23

    APR 2007 2. REPORT TYPE Technical, Success Story 3. DATES COVERED 01-12-2006 to 23-04-2007 4. TITLE AND SUBTITLE Maraging Steel Machining...consumers of cobalt-strengthened maraging steel . An increase in production requires them to reduce the machining time of certain operations producing... maraging steel ; Success Stories 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 1 18. NUMBER OF PAGES 1 19a. NAME OF RESPONSIBLE

  8. Flexible machining systems described

    NASA Astrophysics Data System (ADS)

    Butters, H. J.

    1985-03-01

    The rationalization and gradual automation of short rotationally symmetric parts in the Saalfeld VEB Machine Tool Factory was carried out in three stages: (1) part-specific manufacturing; (2) automated production line for manufacturing toothed gears; and (3) automated manufacturing section for short rotationally symmetric parts. The development of numerically controlled machine tools and of industrial robot technology made possible automated manufacturing. The design of current facilities is explored, manufacturing control is examined, experience is reported.

  9. Human-machine interactions

    DOEpatents

    Forsythe, J. Chris; Xavier, Patrick G.; Abbott, Robert G.; Brannon, Nathan G.; Bernard, Michael L.; Speed, Ann E.

    2009-04-28

    Digital technology utilizing a cognitive model based on human naturalistic decision-making processes, including pattern recognition and episodic memory, can reduce the dependency of human-machine interactions on the abilities of a human user and can enable a machine to more closely emulate human-like responses. Such a cognitive model can enable digital technology to use cognitive capacities fundamental to human-like communication and cooperation to interact with humans.

  10. Metalworking and machining fluids

    DOEpatents

    Erdemir, Ali; Sykora, Frank; Dorbeck, Mark

    2010-10-12

    Improved boron-based metal working and machining fluids. Boric acid and boron-based additives that, when mixed with certain carrier fluids, such as water, cellulose and/or cellulose derivatives, polyhydric alcohol, polyalkylene glycol, polyvinyl alcohol, starch, dextrin, in solid and/or solvated forms result in improved metalworking and machining of metallic work pieces. Fluids manufactured with boric acid or boron-based additives effectively reduce friction, prevent galling and severe wear problems on cutting and forming tools.

  11. Could a machine think

    SciTech Connect

    Churchland, P.M.; Churchland, P.S. )

    1990-01-01

    There are many reasons for saying yes. One of the earliest and deepest reason lay in two important results in computational theory. The first was Church's thesis, which states that every effectively computable function is recursively computable. The second important result was Alan M. Turing's demonstration that any recursively computable function can be computed in finite time by a maximally simple sort of symbol-manipulating machine that has come to be called a universal Turing machine. This machine is guided by a set of recursively applicable rules that are sensitive to the identity, order and arrangement of the elementary symbols it encounters as input. The authors reject the Turing test as a sufficient condition for conscious intelligence. They base their position of the specific behavioral failures of the classical SM machines and on the specific virtues of machines with a more brain-like architecture. These contrasts show that certain computational strategies have vast and decisive advantages over others where typical cognitive tasks are concerned, advantages that are empirically inescapable. Clearly, the brain is making systematic use of these computational advantage. But it need not be the only physical system capable of doing so. Artificial intelligence, in a nonbiological but massively parallel machine, remain a compelling and discernible prospect.

  12. The Knife Machine. Module 15.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    This module on the knife machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers one topic: performing special operations on the knife machine (a single needle or multi-needle machine which sews and cuts at the same time). These components are provided: an introduction, directions, an objective,…

  13. The Buttonhole Machine. Module 13.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    This module on the bottonhole machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers two topics: performing special operations on the buttonhole machine (parts and purpose) and performing special operations on the buttonhole machine (gauged buttonholes). For each topic these components are…

  14. The Knife Machine. Module 15.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    This module on the knife machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers one topic: performing special operations on the knife machine (a single needle or multi-needle machine which sews and cuts at the same time). These components are provided: an introduction, directions, an objective,…

  15. Non-traditional machining techniques

    SciTech Connect

    Day, Robert D; Fierro, Frank; Garcia, Felix P; Hatch, Douglass J; Randolph, Randall B; Reardon, Patrick T; Rivera, Gerald

    2008-01-01

    During the course of machining targets for various experiments it sometimes becomes necessary to adapt fixtures or machines, which are designed for one function, to another function. When adapting a machine or fixture is not adequate, it may be necessary to acquire a machine specifically designed to produce the component required. In addition to the above scenarios, the features of a component may dictate that multi-step machining processes are necessary to produce the component. This paper discusses the machining of four components where adaptation, specialized machine design, or multi-step processes were necessary to produce the components.

  16. One-year clinical outcome after ablation with a novel multipolar irrigated ablation catheter for treatment of atrial fibrillation: potential implications for clinical use.

    PubMed

    Wakili, Reza; Siebermair, Johannes; Fichtner, Stephanie; Sinner, Moritz F; Klocker, Eva; Olesch, Lucia; Hilberath, Jan N; Sarai, Samira; Clauss, Sebastian; Sattler, Stefan; Kääb, Stefan; Estner, Heidi L

    2016-08-01

    Pulmonary vein isolation (PVI) is an established therapy for atrial fibrillation (AF). However, PVI remains a time-consuming procedure. A novel multipolar irrigated radiofrequency (RF) ablation catheter (nMARQ™) is aiming to improve PVI. We investigated the influence on procedural parameters and assessed clinical outcomes after PVI using this novel catheter. Fifty-eight consecutive patients with paroxysmal AF were equally allocated (n = 29/group) to PVI treatment with (i) the novel multipolar ablation catheter (nMARQ™) and (ii) a standard single-tip ablation catheter (SAC). Study endpoints included procedure time, fluoroscopy time, radiation dose, RF time, number of energy applications, and clinical outcome defined as freedom from AF after a single procedure. Successful PVI was confirmed by a separate circular, multipolar mapping catheter in all patients treated with the nMARQ™. Pulmonary vein isolation was achieved in 100% in the SAC group. In the nMARQ™ group, PVI was suggested in all patients. However, confirmatory mapping revealed persistent pulmonary vein (PV) conduction in 19 out of 29 nMARQ™ patients. These patients underwent further ablation, which still failed to achieve PVI in 5 of the 29 nMARQ™ patients, mainly due to significant temperature rise in the oesophagus and device-related limitations reaching the right inferior PV. Mean fluoroscopy time (31 ± 12 vs. 23 ± 10 min, P < 0.05) and (132 ± 37 vs. 109 ± 30 min, P < 0.05) were longer in nMARQ™ vs. SAC patients. Radiofrequency time was shorter in nMARQ™ vs. SAC group (21 ± 9 vs. 35 ± 12 min, P < 0.001). Radiation dose and the number of energy applications did not differ between both groups. Clinical outcome analysis revealed no significant differences (nMARQ™: 72 vs. SAC: 72%) after a mean follow-up of 373 ± 278 days. The use of the nMARQ™ catheter is associated with important device-related limitations to achieve successful PVI. However, clinical outcomes were equivalent in n

  17. Electro-mechanical energy conversion system having a permanent magnet machine with stator, resonant transfer link and energy converter controls

    DOEpatents

    Skeist, S. Merrill; Baker, Richard H.

    2006-01-10

    An electro-mechanical energy conversion system coupled between an energy source and an energy load comprising an energy converter device including a permanent magnet induction machine coupled between the energy source and the energy load to convert the energy from the energy source and to transfer the converted energy to the energy load and an energy transfer multiplexer to control the flow of power or energy through the permanent magnetic induction machine.

  18. Electrostatic Forces: Formulas for the First Derivatives of a Polarizable, Anisotropic Electrostatic Potential Energy Function Based on Machine Learning.

    PubMed

    Mills, Matthew J L; Popelier, Paul L A

    2014-09-09

    Explicit formulas are derived analytically for the first derivatives of a (i) polarizable, (ii) high-rank multipolar electrostatic potential energy function for (iii) flexible molecules. The potential energy function uses a machine learning method called Kriging to predict the local-frame multipole moments of atoms defined via the Quantum Chemical Topology (QCT) approach. These atomic multipole moments then interact via an interaction tensor based on spherical harmonics. Atom-centered local coordinate frames are used, constructed from the internal geometry of the molecular system. The forces involve derivatives of both this geometric dependence and of the trained kriging models. In the near future, these analytical forces will enable molecular dynamics and geometry optimization calculations as part of the QCT force field.

  19. Procedure to Perform Real-Time Reconstruction of the Magnetic Flux in FTU Using RTAI Virtual Machine

    NASA Astrophysics Data System (ADS)

    Sadeghi, Yahya

    2012-06-01

    One of the important topics of plasma equilibrium issue in a tokamak is to determine and reconstruct the magnetic iso-flux surfaces using plasma boundary condition (in Shafranov, Sov Phys JETP Engl Transl 37:775, 1960). The equilibrium code ODIN is based on the technique using the multi-polar moments method (in Alladio and Crisanti, Nuclear Fusion 26:1143, 1986) which results from homogeneous solution of the Grad-Shafranov equation. This method is used to reconstruct the magnetic flux and equilibrium in the Frascati Tokamak Upgrade experiment. The real-time reconstruction of the magnetic field map is important to compute quantities necessary to control the plasma. In this paper we address the procedure to perform real-time reconstruction of the magnetic flux (based on ODIN) on RTAI virtual machine. As result of the real-time implementation, we will show the time evolution of the reconstructed magnetic iso-flux surfaces.

  20. Induction: Making the Leap

    ERIC Educational Resources Information Center

    Ling, Lorraine M.

    2009-01-01

    This article provides a critical examination of a variety of approaches to induction focusing especially upon Australia and other Pacific Rim countries. The question of the purposes induction serves for graduate teachers, experienced teachers and education systems is addressed in terms of whether it is a technical exercise which preserves the…

  1. Foundation doctors' induction experiences.

    PubMed

    Miles, Susan; Kellett, Joanne; Leinster, Sam J

    2015-07-24

    It is well established that trainee doctors struggle with the transition from medical school to starting work and feel unprepared for many aspects of their new role. There is evidence that suitable induction experiences improve competence and confidence, but available data indicate that trainee doctors on the UK Foundation Programme are commonly not experiencing useful inductions. The aim of the reported research was to explore trainee doctors' experiences with induction during their first year of the Foundation Programme to identify the most useful characteristics. A questionnaire was designed to explore trainee doctors' experiences with induction at two points during their first Foundation year, during the first and third of three rotations, to enable all induction experiences on offer during the year to be surveyed. Data were collected using an anonymous questionnaire distributed during a teaching session, with an online version available for those trainees not present. Questions gathered information about characteristics of the inductions, usefulness of components of the inductions and what gaps exist. 192 Foundation trainee doctors completed the questionnaire during Rotation 1 and 165 during Rotation 3. The findings indicated that induction experiences at the beginning of the year, including the local Preparation for Professional Practice week, were more useful than those received for later rotations. Longer inductions were more useful than shorter. Departmental inductions were generally only moderately helpful and they missed many important characteristics. Gaps in their inductions identified by many trainees matched those aspects judged to be most useful by those trainees who had experienced these characteristics. Many Foundation trainee doctors are experiencing inadequate inductions, notably at the department level. Trainees are starting rotations in new departments without rudimentary knowledge about their role and responsibilities in that department

  2. Principles of Induction Accelerators

    NASA Astrophysics Data System (ADS)

    Briggs*, Richard J.

    The basic concepts involved in induction accelerators are introduced in this chapter. The objective is to provide a foundation for the more detailed coverage of key technology elements and specific applications in the following chapters. A wide variety of induction accelerators are discussed in the following chapters, from the high current linear electron accelerator configurations that have been the main focus of the original developments, to circular configurations like the ion synchrotrons that are the subject of more recent research. The main focus in the present chapter is on the induction module containing the magnetic core that plays the role of a transformer in coupling the pulsed power from the modulator to the charged particle beam. This is the essential common element in all these induction accelerators, and an understanding of the basic processes involved in its operation is the main objective of this chapter. (See [1] for a useful and complementary presentation of the basic principles in induction linacs.)

  3. Extreme ultraviolet lithography machine

    DOEpatents

    Tichenor, Daniel A.; Kubiak, Glenn D.; Haney, Steven J.; Sweeney, Donald W.

    2000-01-01

    An extreme ultraviolet lithography (EUVL) machine or system for producing integrated circuit (IC) components, such as transistors, formed on a substrate. The EUVL machine utilizes a laser plasma point source directed via an optical arrangement onto a mask or reticle which is reflected by a multiple mirror system onto the substrate or target. The EUVL machine operates in the 10-14 nm wavelength soft x-ray photon. Basically the EUV machine includes an evacuated source chamber, an evacuated main or project chamber interconnected by a transport tube arrangement, wherein a laser beam is directed into a plasma generator which produces an illumination beam which is directed by optics from the source chamber through the connecting tube, into the projection chamber, and onto the reticle or mask, from which a patterned beam is reflected by optics in a projection optics (PO) box mounted in the main or projection chamber onto the substrate. In one embodiment of a EUVL machine, nine optical components are utilized, with four of the optical components located in the PO box. The main or projection chamber includes vibration isolators for the PO box and a vibration isolator mounting for the substrate, with the main or projection chamber being mounted on a support structure and being isolated.

  4. Organisms ≠ Machines.

    PubMed

    Nicholson, Daniel J

    2013-12-01

    The machine conception of the organism (MCO) is one of the most pervasive notions in modern biology. However, it has not yet received much attention by philosophers of biology. The MCO has its origins in Cartesian natural philosophy, and it is based on the metaphorical redescription of the organism as a machine. In this paper I argue that although organisms and machines resemble each other in some basic respects, they are actually very different kinds of systems. I submit that the most significant difference between organisms and machines is that the former are intrinsically purposive whereas the latter are extrinsically purposive. Using this distinction as a starting point, I discuss a wide range of dissimilarities between organisms and machines that collectively lay bare the inadequacy of the MCO as a general theory of living systems. To account for the MCO's prevalence in biology, I distinguish between its theoretical, heuristic, and rhetorical functions. I explain why the MCO is valuable when it is employed heuristically but not theoretically, and finally I illustrate the serious problems that arise from the rhetorical appeal to the MCO. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. The Bearingless Electrical Machine

    NASA Technical Reports Server (NTRS)

    Bichsel, J.

    1992-01-01

    Electromagnetic bearings allow the suspension of solids. For rotary applications, the most important physical effect is the force of a magnetic circuit to a high permeable armature, called the MAXWELL force. Contrary to the commonly used MAXWELL bearings, the bearingless electrical machine will take advantage of the reaction force of a conductor carrying a current in a magnetic field. This kind of force, called Lorentz force, generates the torque in direct current, asynchronous and synchronous machines. The magnetic field, which already exists in electrical machines and helps to build up the torque, can also be used for the suspension of the rotor. Besides the normal winding of the stator, a special winding was added, which generates forces for levitation. So a radial bearing, which is integrated directly in the active part of the machine, and the motor use the laminated core simultaneously. The winding was constructed for the levitating forces in a special way so that commercially available standard ac inverters for drives can be used. Besides wholly magnetic suspended machines, there is a wide range of applications for normal drives with ball bearings. Resonances of the rotor, especially critical speeds, can be damped actively.

  6. Transferred multipolar atom model for 10β,17β-dihydroxy-17α-methylestr-4-en-3-one dihydrate obtained from the biotransformation of methyloestrenolone.

    PubMed

    Faroque, Muhammad Umer; Yousuf, Sammer; Zafar, Salman; Choudhary, M Iqbal; Ahmed, Maqsood

    2016-05-01

    Biotransformation is the structural modification of compounds using enzymes as the catalysts and it plays a key role in the synthesis of pharmaceutically important compounds. 10β,17β-Dihydroxy-17α-methylestr-4-en-3-one dihydrate, C19H28O3·2H2O, was obtained from the fungal biotransformation of methyloestrenolone. The structure was refined using the classical independent atom model (IAM) and a transferred multipolar atom model using the ELMAM2 database. The results from the two refinements have been compared. The ELMAM2 refinement has been found to be superior in terms of the refinement statistics. It has been shown that certain electron-density-derived properties can be calculated on the basis of the transferred parameters for crystals which diffract to ordinary resolution.

  7. Multi-Frequency and Multi-Polarization Study on SAR-Based Coastal AReas Characterization: The Case of the Yellow River Delta

    NASA Astrophysics Data System (ADS)

    Buono, Andrea; Nunziata, Ferdinando; Migliaccio, Maurizio; Li, Xiaofeng; Shen, Dongliang; Ding, Xianwen

    2016-08-01

    The Yellow River is the most sediment-filled river and the sixth-longest one in the world. It is of paramount importance for safe navigation, local economy and environment due to the presence of floods, farms, aquacultures and pollution. Further, the Yellow River delta is characterized by several physical phenomena due to both natural and anthropogenic processes: sedimentation, erosion, floods, pollution, etc.In this study, actual partially-overlapped L-/C-band fully- polarimetric (FP) synthetic aperture radar (SAR) data are used to investigate the scattering properties of the Yellow River delta, whose very complex area is characterized by different environments as recorded by ground truth data acquired during a ship-based in-situ campaign. Preliminary results witness that multi-polarization and multi-frequency SAR measurements allow inferring more physical information in such a complex environment that can be used as starting point for developing ad hoc classification algorithms.

  8. A theoretical analysis of HLA-DRbeta1*0301-CLIP complex using the first three multipolar moments of the electrostatic field.

    PubMed

    Balbín, Alejandro; Cárdenas, Constanza; Villaveces, José Luis; Patarroyo, Manuel E

    2006-09-01

    Interactions between the HLA-DRbeta1*0301 molecule and several occupying peptides obtained from computational substitutions made to the CLIP peptide are studied. The exploration was carried out using a vector composed of the first three terms of the multipolar expansion of the electrostatic field, namely, charge (q), dipole (d) and quadrupole (C). Comparisons between pocket-peptide interactions established that the binding pockets for this HLA molecule are ordered in terms of their importance for binding peptides, as follows: P1 > P4 > P6 > P7 > P9. A set of electrostatically distinct amino acids that determine interaction stability and specificity were identified for each pocket. The beta74R residue was especially identified as being the key amino acid mediating the occupying peptide binding for pocket 4; this residue has been recently associated with Graves' disease.

  9. Per-point and per-field contextual classification of multipolarization and multiple incidence angle aircraft L-band radar data

    NASA Technical Reports Server (NTRS)

    Hoffer, Roger M.; Hussin, Yousif Ali

    1989-01-01

    Multipolarized aircraft L-band radar data are classified using two different image classification algorithms: (1) a per-point classifier, and (2) a contextual, or per-field, classifier. Due to the distinct variations in radar backscatter as a function of incidence angle, the data are stratified into three incidence-angle groupings, and training and test data are defined for each stratum. A low-pass digital mean filter with varied window size (i.e., 3x3, 5x5, and 7x7 pixels) is applied to the data prior to the classification. A predominately forested area in northern Florida was the study site. The results obtained by using these image classifiers are then presented and discussed.

  10. Brown coal preparation machines

    SciTech Connect

    Bleckmann, H.; Sitte, W.; Kellerwessel, H.

    1981-05-01

    Lignite usually requires comminuting and screening before being used as a fuel in power plants. Reduction machines normally used for coarse crushing bituminous coal, such as jaw crushers, roll crushers, and impact crushers, are not generally suitable for lignite as they require a brittle feed and large grain size. In contrast to these requirements, lignite can be easily compressed and has a small grain size. Therefore, special crusher types have been developed for the coarse reduction of lignite. These machines resemble roll crushers but subject the feed to shearing and tearing forces rather than to compressive stress. It is often necessary to screen the lignite to remove the undersize or to limit the maximum particle size before the next comminution process. Screening the lignite is a particularly difficult operation due to the high water content and the presence of clay minerals which tend to clog the screening machines. These problems can be overcome with multi-roll sizers.

  11. Micro-machined resonator

    DOEpatents

    Godshall, N.A.; Koehler, D.R.; Liang, A.Y.; Smith, B.K.

    1993-03-30

    A micro-machined resonator, typically quartz, with upper and lower micro-machinable support members, or covers, having etched wells which may be lined with conductive electrode material, between the support members is a quartz resonator having an energy trapping quartz mesa capacitively coupled to the electrode through a diaphragm; the quartz resonator is supported by either micro-machined cantilever springs or by thin layers extending over the surfaces of the support. If the diaphragm is rigid, clock applications are available, and if the diaphragm is resilient, then transducer applications can be achieved. Either the thin support layers or the conductive electrode material can be integral with the diaphragm. In any event, the covers are bonded to form a hermetic seal and the interior volume may be filled with a gas or may be evacuated. In addition, one or both of the covers may include oscillator and interface circuitry for the resonator.

  12. Micro-machined resonator

    DOEpatents

    Godshall, Ned A.; Koehler, Dale R.; Liang, Alan Y.; Smith, Bradley K.

    1993-01-01

    A micro-machined resonator, typically quartz, with upper and lower micro-machinable support members, or covers, having etched wells which may be lined with conductive electrode material, between the support members is a quartz resonator having an energy trapping quartz mesa capacitively coupled to the electrode through a diaphragm; the quartz resonator is supported by either micro-machined cantilever springs or by thin layers extending over the surfaces of the support. If the diaphragm is rigid, clock applications are available, and if the diaphragm is resilient, then transducer applications can be achieved. Either the thin support layers or the conductive electrode material can be integral with the diaphragm. In any event, the covers are bonded to form a hermetic seal and the interior volume may be filled with a gas or may be evacuated. In addition, one or both of the covers may include oscillator and interface circuitry for the resonator.

  13. Was the Devonian geomagnetic field dipolar or multipolar? Palaeointensity studies of Devonian igneous rocks from the Minusa Basin (Siberia) and the Kola Peninsula dykes, Russia

    NASA Astrophysics Data System (ADS)

    Shcherbakova, V. V.; Biggin, A. J.; Veselovskiy, R. V.; Shatsillo, A. V.; Hawkins, L. M. A.; Shcherbakov, V. P.; Zhidkov, G. V.

    2017-05-01

    Defining variations in the behaviour of the geomagnetic field through geological time is critical to understanding the dynamics of Earth's core and its response to mantle convection and planetary evolution. Furthermore, the question of whether the axial dipole dominance of the recent palaeomagnetic field persists through the whole of Earth's history is fundamental to determining the reliability of palaeogeographic reconstructions and the efficacy of the magnetosphere in shielding Earth from solar wind radiation. Previous palaeomagnetic directional studies have suggested that the palaeofield had a complex configuration in the Devonian period (419-359 Ma). Here we present new high-quality palaeointensity determinations from rocks aged between 408 and 375 Ma from the Minusa Basin (southern Siberia), and the Kola Peninsula that enable the first reliable investigation of the strength of the field during this enigmatic period. Palaeointensity experiments were performed using the thermal Thellier, microwave Thellier and Wilson methods on 165 specimens from 25 sites. Six out of eight successful sites from the Minusa Basin and all four successful sites from the Kola Peninsula produced extremely low palaeointensities (<10 μT). These findings challenge the uniformitarian view of the palaeomagnetic field: field intensities of nearly an order of magnitude lower than Neogene values (except during relatively rare geomagnetic excursions and reversals) together with the widespread appearance of strange directions found in the Devonian suggest that the Earth's field during this time may have had a dominantly multipolar geometry. A persistent, low intensity multipolar magnetic field and associated diminished magnetosphere would increase the impact of solar particles on the Earth's magnetosphere, ionosphere and atmosphere with potential major implications for Earth's climate and biosphere.

  14. Reduction of Fluoroscopic Exposure Using a New Fluoroscopy Integrating Technology in a 3D-Mapping System During Pulmonary Vein Isolation With a Circular Multipolar Irrigated Catheter.

    PubMed

    Blockhaus, Christian; Schmidt, Jan; Kurt, Muhammed; Clasen, Lukas; Brinkmeyer, Christoph; Katsianos, Efstratios; Müller, Patrick; Gerguri, Shqipe; Kelm, Malte; Shin, Dong-In; Makimoto, Hisaki

    2016-05-25

    Pulmonary vein isolation (PVI) is a cornerstone therapy in patients with atrial fibrillation (AF). With increasing numbers of PVI procedures, demand arises to reduce the cumulative fluoroscopic radiation exposure for both the physician and the patient. New technologies are emerging to address this issue. Here, we report our first experiences with a new fluoroscopy integrating technology in addition to a current 3D-mapping system. The new fluoroscopy integrating system (FIS) with 3D-mapping was used prospectively in 15 patients with AF. Control PVI cases (n = 37) were collected retrospectively as a complete series. Total procedure time (skin to skin), fluoroscopic time, and dose-area-product (DAP) data were analyzed. All PVI procedures were performed by one experienced physician using a commercially available circular multipolar irrigated ablation catheter. All PVI procedures were successfully undertaken without major complications. Baseline characteristics of the two groups showed no significant differences. In the group using the FIS, the fluoroscopic time and DAP were significantly reduced from 571 ± 187 seconds versus 1011 ± 527 seconds (P = 0.0029) and 4342 ± 2073 cGycm(2) versus 6208 ± 3314 cGycm(2) (P = 0.049), respectively. Mean procedure time was not significantly affected and was 114 ± 31 minutes versus 104 ± 24 minutes (P = 0.23) by the FIS.The use of the new FIS with the current 3D-mapping system enables a significant reduction of the total fluoroscopy time and DAP compared to the previous combination of 3D-mapping system plus normal fluoroscopy during PVI utilizing a circular multipolar irrigated ablation catheter. However, the concomitant total procedure time is not affected. Thus, the new system reduces the radiation exposure for both the physicians and patients.

  15. Was the Devonian geomagnetic field dipolar or multipolar? Palaeointensity studies of Devonian igneous rocks from the Minusa Basin (Siberia) and the Kola Peninsula dykes, Russia

    NASA Astrophysics Data System (ADS)

    Shcherbakova, V. V.; Biggin, A. J.; Veselovskiy, R. V.; Shatsillo, A. V.; Hawkins, L.; Shcherbakov, V. P.; Zhidkov, G. V.

    2017-02-01

    Defining variations in the behaviour of the geomagnetic field through geological time is critical to understanding the dynamics of Earth's core and its response to mantle convection and planetary evolution. Furthermore, the question of whether the axial dipole dominance of the recent palaeomagnetic field persists through the whole of Earth's history is fundamental to determining the reliability of palaeogeographic reconstructions and the efficacy of the magnetosphere in shielding Earth from solar wind radiation. Previous palaeomagnetic directional studies have suggested that the palaeofield had a complex configuration in the Devonian period (419-359 Ma). Here we present new palaeointensity determinations from rocks aged between 408 and 375 Ma from the Minusa Basin (southern Siberia), and the Kola Peninsula to investigate the strength of the field during this enigmatic period. Palaeointensity experiments were performed using the thermal Thellier, microwave Thellier, and Wilson methods on 165 specimens from 25 sites. Six out of eight successful sites from the Minusa Basin and all four successful sites from the Kola Peninsula produced extremely low palaeointensities (< 10 μT). These findings challenge the uniformitarian view of the palaeomagnetic field: field intensities of nearly an order of magnitude lower than Neogene values (except during relatively rare geomagnetic excursions and reversals) together with the widespread appearance of strange directions found in the Devonian suggest that the Earth's field during this time may have had a dominantly multipolar geometry. A persistent, low intensity multipolar magnetic field and associated diminished magnetosphere would increase the impact of solar particles on the Earth's magnetosphere, ionosphere and atmosphere with potential major implications for Earth's climate and biosphere.

  16. [transversion of cell polarity from Bi- to multipolarity is the mechanism determining multiple spore formation in Anaerobacter polyendosporus PS-1T].

    PubMed

    Duda, V I; Suzina, N E; Polivtseva, V N; Gafarov, A B; Shorokhova, A P; Machulin, A V

    2014-01-01

    The number of spores formed in a single cell ofAnaerobacterpolyendosporus PS-1T is significantly influenced by the composition of nutrient media. Depending on carbohydrate concentration in synthetic medium, the number of spores may vary from one-two to five-seven. Investigation of spore formation by fluorescence and electron microscopy revealed that on media with 0.5-1.0% glucose or galactose most of the vegetative cells remained rod-shaped after cessation of cell division in the culture. Their nucleoids were localized at cell poles close to the polar site of the cytoplasmic membrane. Forespores were formed at one or both of these poles. A satellite nucleoid (operator) was detected close to each forespore. In the variant with bipolar organization of mother cells only one or two spores per cell were formed. In the second variant of cultivation, when the cells grew at low galactose concentrations (0.1-0.3%), most of the vegetative cells increased in volume and became oval or spherical after cessation of cell division in the culture. Epifluorescence microscopy with nucleic acids-specific fluorochromes (DAPI and acridine orange) revealed the presence of multiple (six to nine) nucleoids in these cells. The nucleoids were located at the cell periphery in close contact with the cytoplasmic membrane. These nucleoids became the centers (poles) for forespore formation. Thus, in the early stationary phase transversion from bipolar to multipolar cells occurred during the early stationary phase. Cessation of cell division combined with continuing replication of the nucleoids resulted in formation on multinuclear cells. The multiplicity of nucleoides and multipolarity of these cells were prerequisites determining endogenous polysporogenesis, occurring as synchronous formation of three to seven twin spores in a number of the oval and spherical cells.

  17. Paradigms for machine learning

    NASA Technical Reports Server (NTRS)

    Schlimmer, Jeffrey C.; Langley, Pat

    1991-01-01

    Five paradigms are described for machine learning: connectionist (neural network) methods, genetic algorithms and classifier systems, empirical methods for inducing rules and decision trees, analytic learning methods, and case-based approaches. Some dimensions are considered along with these paradigms vary in their approach to learning, and the basic methods are reviewed that are used within each framework, together with open research issues. It is argued that the similarities among the paradigms are more important than their differences, and that future work should attempt to bridge the existing boundaries. Finally, some recent developments in the field of machine learning are discussed, and their impact on both research and applications is examined.

  18. Autonomous quantum thermodynamic machines

    NASA Astrophysics Data System (ADS)

    Tonner, Friedemann; Mahler, Günter

    2005-12-01

    We investigate the dynamics of a quantum system consisting of a single spin coupled to an oscillator and sandwiched between two thermal baths at different temperatures. By means of an adequately designed Lindblad equation, it is shown that this device can function as a thermodynamic machine exhibiting Carnot-type cycles. For the present model, this means that when run as a heat engine, coherent motion of the oscillator is amplified. Contrary to the quantum computer, such a machine has a quantum as well as a classical limit. Away from the classical limit, it asymptotically approaches a stationary transport scenario.

  19. Refrigerating machine oil

    SciTech Connect

    Nozawa, K.

    1981-03-17

    Refrigerating machine oil to be filled in a sealed motorcompressor unit constituting a refrigerating cycle system including an electric refrigerator, an electric cold-storage box, a small-scaled electric refrigerating show-case, a small-scaled electric cold-storage show-case and the like, is arranged to have a specifically enhanced property, in which smaller initial driving power consumption of the sealed motor-compressor and easier supply of the predetermined amount of the refrigerating machine oil to the refrigerating system are both guaranteed even in a rather low environmental temperature condition.

  20. Intersecting vane machines

    DOEpatents

    Bailey, H. Sterling; Chomyszak, Stephen M.

    2007-01-16

    The invention provides a toroidal intersecting vane machine incorporating intersecting rotors to form primary and secondary chambers whose porting configurations minimize friction and maximize efficiency. Specifically, it is an object of the invention to provide a toroidal intersecting vane machine that greatly reduces the frictional losses through meshing surfaces without the need for external gearing by modifying the function of one or the other of the rotors from that of "fluid moving" to that of "valving" thereby reducing the pressure loads and associated inefficiencies at the interface of the meshing surfaces. The inventions described herein relate to these improvements.

  1. Precision Robotic Assembly Machine

    ScienceCinema

    None

    2016-07-12

    The world's largest laser system is the National Ignition Facility (NIF), located at Lawrence Livermore National Laboratory. NIF's 192 laser beams are amplified to extremely high energy, and then focused onto a tiny target about the size of a BB, containing frozen hydrogen gas. The target must be perfectly machined to incredibly demanding specifications. The Laboratory's scientists and engineers have developed a device called the "Precision Robotic Assembly Machine" for this purpose. Its unique design won a prestigious R&D-100 award from R&D Magazine.

  2. Precision Robotic Assembly Machine

    SciTech Connect

    2009-08-14

    The world's largest laser system is the National Ignition Facility (NIF), located at Lawrence Livermore National Laboratory. NIF's 192 laser beams are amplified to extremely high energy, and then focused onto a tiny target about the size of a BB, containing frozen hydrogen gas. The target must be perfectly machined to incredibly demanding specifications. The Laboratory's scientists and engineers have developed a device called the "Precision Robotic Assembly Machine" for this purpose. Its unique design won a prestigious R&D-100 award from R&D Magazine.

  3. New photolithography stepping machine

    SciTech Connect

    Hale, L.; Klingmann, J.; Markle, D.

    1995-03-08

    A joint development project to design a new photolithography steeping machine capable of 150 nanometer overlay accuracy was completed by Ultratech Stepper and the Lawrence Livermore National Laboratory. The principal result of the project is a next-generation product that will strengthen the US position in step-and-repeat photolithography. The significant challenges addressed and solved in the project are the subject of this report. Design methods and new devices that have broader application to precision machine design are presented in greater detail while project specific information serves primarily as background and motivation.

  4. Machining in Microgravity

    NASA Astrophysics Data System (ADS)

    Vincent, Graylan

    2003-01-01

    A CNC mill was flown aboard NASA's KC-135 ``Weightless Wonder'' microgravity research aircraft to investigate the effect of gravity on the machining process and to demonstrate the feasibility and functionality of a CNC mill in a weightless environment, such as aboard the International Space Station. The experiment hypothesis was that the surface roughness of milling cuts made in microgravity would be of higher quality than cuts made in a gravitational environment due to increased chip removal. The technical problems associated with microgravity machining (such as the chip removal and collection process), and the engineering solutions to these problems were also evaluated in this experiment.

  5. Automated fiber pigtailing machine

    DOEpatents

    Strand, Oliver T.; Lowry, Mark E.

    1999-01-01

    The Automated Fiber Pigtailing Machine (AFPM) aligns and attaches optical fibers to optoelectonic (OE) devices such as laser diodes, photodiodes, and waveguide devices without operator intervention. The so-called pigtailing process is completed with sub-micron accuracies in less than 3 minutes. The AFPM operates unattended for one hour, is modular in design and is compatible with a mass production manufacturing environment. This machine can be used to build components which are used in military aircraft navigation systems, computer systems, communications systems and in the construction of diagnostics and experimental systems.

  6. Automated fiber pigtailing machine

    DOEpatents

    Strand, O.T.; Lowry, M.E.

    1999-01-05

    The Automated Fiber Pigtailing Machine (AFPM) aligns and attaches optical fibers to optoelectronic (OE) devices such as laser diodes, photodiodes, and waveguide devices without operator intervention. The so-called pigtailing process is completed with sub-micron accuracies in less than 3 minutes. The AFPM operates unattended for one hour, is modular in design and is compatible with a mass production manufacturing environment. This machine can be used to build components which are used in military aircraft navigation systems, computer systems, communications systems and in the construction of diagnostics and experimental systems. 26 figs.

  7. Automated Discovery of Machine-Specific Code Improvements

    DTIC Science & Technology

    1984-12-01

    32 ·-1 Lemma 1: There are n X E Pr comparisons required to find all complete matches of l ength r-o k, and all partial matches of up to length k...These extensions generate at most n Xpr partial matches of length l + 1. Since Pr < n 1 by the induction hypothesis, which extends the induction. P1+1...Prescribed by ANSI Std Z39-18 Automated Discovery of Machine-Specific Code Impro vements Copyright @ 1984 by Peter Bernard Kessler If I had the

  8. How induction generators work

    SciTech Connect

    Nailen, R.L.

    1980-06-01

    The operating principles of the induction generator, which is a standard squirrel cage motor in which the shaft is coupled to and driven by an engine or turbine at a rate above its synchronous speed and which, under these conditions, produces electrical power, are described. The advantages of induction generators, e.g., low cost, simplicity, frequency and voltage controlled by the utility system, no synchronizing controls needed, and the advantages of using small induction generators run by wind turbines, small gas turbines and in low head hydro plants are discussed. (LCL)

  9. Direct reading inductance meter

    NASA Technical Reports Server (NTRS)

    Kolby, R. B. (Inventor)

    1977-01-01

    A direct reading inductance meter comprised of a crystal oscillator and an LC tuned oscillator is presented. The oscillators function respectively to generate a reference frequency, f(r), and to generate an initial frequency, f(0), which when mixed produce a difference equal to zero. Upon connecting an inductor of small unknown value in the LC circuit to change its resonant frequency to f(x), a difference frequency (f(r)-f(x)) is produced that is very nearly a linear function of the inductance of the inductor. The difference frequency is measured and displayed on a linear scale in units of inductance.

  10. Properties of inductive reasoning.

    PubMed

    Heit, E

    2000-12-01

    This paper reviews the main psychological phenomena of inductive reasoning, covering 25 years of experimental and model-based research, in particular addressing four questions. First, what makes a case or event generalizable to other cases? Second, what makes a set of cases generalizable? Third, what makes a property or predicate projectable? Fourth, how do psychological models of induction address these results? The key results in inductive reasoning are outlined, and several recent models, including a new Bayesian account, are evaluated with respect to these results. In addition, future directions for experimental and model-based work are proposed.

  11. 14. Machine in north 1922 section of Building 59. Machine ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Machine in north 1922 section of Building 59. Machine is 24' Jointer made by Oliver Machinery Co. Camera pointed E. - Puget Sound Naval Shipyard, Pattern Shop, Farragut Avenue, Bremerton, Kitsap County, WA

  12. BRASS FOUNDRY MACHINE ROOM USED TO MACHINE CAST BRONZE PIECES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    BRASS FOUNDRY MACHINE ROOM USED TO MACHINE CAST BRONZE PIECES FOR VALVES AND PREPARE BRONZE VALVE BODIES FOR ASSEMBLY. - Stockham Pipe & Fittings Company, Brass Foundry, 4000 Tenth Avenue North, Birmingham, Jefferson County, AL

  13. 12. Photocopied August 1978. CHANNELING MACHINES, NOVEMBER 1898. THESE MACHINES ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photocopied August 1978. CHANNELING MACHINES, NOVEMBER 1898. THESE MACHINES BLOCKED OUT SECTIONS IN THE ROCK CUT IN PREPARATION FOR DRILLING AND BLASTING. (17) - Michigan Lake Superior Power Company, Portage Street, Sault Ste. Marie, Chippewa County, MI

  14. 42. MACHINE SHOP Machine shop area with small parts bins ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    42. MACHINE SHOP Machine shop area with small parts bins on the right and pipe storage racks on the left. Remains of the power drive system are suspended from the ceiling. - Hovden Cannery, 886 Cannery Row, Monterey, Monterey County, CA

  15. Machine speech and speaking about machines

    SciTech Connect

    Nye, A.

    1996-12-31

    Current philosophy of language prides itself on scientific status. It boasts of being no longer contaminated with queer mental entities or idealist essences. It theorizes language as programmable variants of formal semantic systems, reimaginable either as the properly epiphenomenal machine functions of computer science or the properly material neural networks of physiology. Whether or not such models properly capture the physical workings of a living human brain is a question that scientists will have to answer. I, as a philosopher, come at the problem from another direction. Does contemporary philosophical semantics, in its dominant truth-theoretic and related versions, capture actual living human thought as it is experienced, or does it instead reflect, regardless of (perhaps dubious) scientific credentials, pathology of thought, a pathology with a disturbing social history.

  16. Support vector machines

    NASA Technical Reports Server (NTRS)

    Garay, Michael J.; Mazzoni, Dominic; Davies, Roger; Wagstaff, Kiri

    2004-01-01

    Support Vector Machines (SVMs) are a type of supervised learning algorith,, other examples of which are Artificial Neural Networks (ANNs), Decision Trees, and Naive Bayesian Classifiers. Supervised learning algorithms are used to classify objects labled by a 'supervisor' - typically a human 'expert.'.

  17. The Answer Machine.

    ERIC Educational Resources Information Center

    Feldman, Susan

    2000-01-01

    Discusses information retrieval systems and the need to have them adapt to user needs, integrate information in any format, reveal patterns and trends in information, and answer questions. Topics include statistics and probability; natural language processing; intelligent agents; concept mapping; machine-aided indexing; text mining; filtering;…

  18. Machine Parts as Metaphor.

    ERIC Educational Resources Information Center

    Porter, Gerald

    The connection between Language for Specific Purposes (LSP) and literature is discussed with examples of technical vocabulary drawn from a variety of writers, with particular attention to a sketch by the British dramatist Harold Pinter, "Trouble in the Works," which makes extensive use of the terminology of machine parts. It is noted…

  19. Laser machining of explosives

    SciTech Connect

    Perry, Michael D.; Stuart, Brent C.; Banks, Paul S.; Myers, Booth R.; Sefcik, Joseph A.

    2000-01-01

    The invention consists of a method for machining (cutting, drilling, sculpting) of explosives (e.g., TNT, TATB, PETN, RDX, etc.). By using pulses of a duration in the range of 5 femtoseconds to 50 picoseconds, extremely precise and rapid machining can be achieved with essentially no heat or shock affected zone. In this method, material is removed by a nonthermal mechanism. A combination of multiphoton and collisional ionization creates a critical density plasma in a time scale much shorter than electron kinetic energy is transferred to the lattice. The resulting plasma is far from thermal equilibrium. The material is in essence converted from its initial solid-state directly into a fully ionized plasma on a time scale too short for thermal equilibrium to be established with the lattice. As a result, there is negligible heat conduction beyond the region removed resulting in negligible thermal stress or shock to the material beyond a few microns from the laser machined surface. Hydrodynamic expansion of the plasma eliminates the need for any ancillary techniques to remove material and produces extremely high quality machined surfaces. There is no detonation or deflagration of the explosive in the process and the material which is removed is rendered inert.

  20. History of wood machining

    Treesearch

    Peter Koch

    1967-01-01

    The history of wood machining is closely tied to advanced in metallurgy and power sources. It has been strongly and continuously shaped by prevailing economic forces and the rise and decline of other contemporary industries. This paper sketches a few of the highlights, with emphasis on developments in North America.

  1. Copy Machine Art.

    ERIC Educational Resources Information Center

    Sommer, Jean

    1984-01-01

    Images created with copy machines make children feel successful, as their work acquires the authority of being printed. Students can learn advanced processes like electrostatic image-making and can get involved in projects like making collages. They acquire an appreciation of design and of two-dimensional composition. (CS)

  2. Biomimetic machine vision system.

    PubMed

    Harman, William M; Barrett, Steven F; Wright, Cameron H G; Wilcox, Michael

    2005-01-01

    Real-time application of digital imaging for use in machine vision systems has proven to be prohibitive when used within control systems that employ low-power single processors without compromising the scope of vision or resolution of captured images. Development of a real-time machine analog vision system is the focus of research taking place at the University of Wyoming. This new vision system is based upon the biological vision system of the common house fly. Development of a single sensor is accomplished, representing a single facet of the fly's eye. This new sensor is then incorporated into an array of sensors capable of detecting objects and tracking motion in 2-D space. This system "preprocesses" incoming image data resulting in minimal data processing to determine the location of a target object. Due to the nature of the sensors in the array, hyperacuity is achieved thereby eliminating resolutions issues found in digital vision systems. In this paper, we will discuss the biological traits of the fly eye and the specific traits that led to the development of this machine vision system. We will also discuss the process of developing an analog based sensor that mimics the characteristics of interest in the biological vision system. This paper will conclude with a discussion of how an array of these sensors can be applied toward solving real-world machine vision issues.

  3. Cybernetic anthropomorphic machine systems

    NASA Technical Reports Server (NTRS)

    Gray, W. E.

    1974-01-01

    Functional descriptions are provided for a number of cybernetic man machine systems that augment the capacity of normal human beings in the areas of strength, reach or physical size, and environmental interaction, and that are also applicable to aiding the neurologically handicapped. Teleoperators, computer control, exoskeletal devices, quadruped vehicles, space maintenance systems, and communications equipment are considered.

  4. Working with Simple Machines

    ERIC Educational Resources Information Center

    Norbury, John W.

    2006-01-01

    A set of examples is provided that illustrate the use of work as applied to simple machines. The ramp, pulley, lever and hydraulic press are common experiences in the life of a student, and their theoretical analysis therefore makes the abstract concept of work more real. The mechanical advantage of each of these systems is also discussed so that…

  5. Protein thin film machines.

    PubMed

    Federici, Stefania; Oliviero, Giulio; Hamad-Schifferli, Kimberly; Bergese, Paolo

    2010-12-01

    We report the first example of microcantilever beams that are reversibly driven by protein thin film machines fueled by cycling the salt concentration of the surrounding solution. We also show that upon the same salinity stimulus the drive can be completely reversed in its direction by introducing a surface coating ligand. Experimental results are throughout discussed within a general yet simple thermodynamic model.

  6. Support vector machines

    NASA Technical Reports Server (NTRS)

    Garay, Michael J.; Mazzoni, Dominic; Davies, Roger; Wagstaff, Kiri

    2004-01-01

    Support Vector Machines (SVMs) are a type of supervised learning algorith,, other examples of which are Artificial Neural Networks (ANNs), Decision Trees, and Naive Bayesian Classifiers. Supervised learning algorithms are used to classify objects labled by a 'supervisor' - typically a human 'expert.'.

  7. Machine Aids to Translation.

    ERIC Educational Resources Information Center

    Brinkmann, Karl-Heinz

    1981-01-01

    Describes the TEAM Program System of the Siemens Language Services Department, particularly the main features of its terminology data bank. Discusses criteria to which stored terminology must conform and methods of data bank utilization. Concludes by summarizing the consequences that machine-aided translation development has had for the…

  8. The Art Machine.

    ERIC Educational Resources Information Center

    Vertelney, Harry; Grossberger, Lucia

    1983-01-01

    Introduces educators to possibilities of computer graphics using an inexpensive computer system which takes advantage of existing equipment (35mm camera, super 8 movie camera, VHS video cassette recorder). The concept of the "art machine" is explained, highlighting input and output devices (X-Y plotter, graphic tablets, video…

  9. Working with Simple Machines

    ERIC Educational Resources Information Center

    Norbury, John W.

    2006-01-01

    A set of examples is provided that illustrate the use of work as applied to simple machines. The ramp, pulley, lever and hydraulic press are common experiences in the life of a student, and their theoretical analysis therefore makes the abstract concept of work more real. The mechanical advantage of each of these systems is also discussed so that…

  10. Machine Aids to Translation.

    ERIC Educational Resources Information Center

    Brinkmann, Karl-Heinz

    1981-01-01

    Describes the TEAM Program System of the Siemens Language Services Department, particularly the main features of its terminology data bank. Discusses criteria to which stored terminology must conform and methods of data bank utilization. Concludes by summarizing the consequences that machine-aided translation development has had for the…

  11. Introduction to Exploring Machines

    ERIC Educational Resources Information Center

    Early Childhood Today, 2006

    2006-01-01

    Young children are fascinated by how things "work." They are at a stage of development where they want to experiment with the many ways to use an object or take things apart and put them back together. In the process of exploring tools and machines, children use the scientific method and problem-solving skills. They observe how things work, wonder…

  12. Giving Machines the Vision

    NASA Technical Reports Server (NTRS)

    1999-01-01

    Amherst Systems manufactures foveal machine vision technology and systems commercially available to end-users and system integrators. This technology was initially developed under NASA contracts NAS9-19335 (Johnson Space Center) and NAS1-20841 (Langley Research Center). This technology is currently being delivered to university research facilities and military sites. More information may be found in www.amherst.com.

  13. Electrical Discharge Machining.

    ERIC Educational Resources Information Center

    Montgomery, C. M.

    The manual is for use by students learning electrical discharge machining (EDM). It consists of eight units divided into several lessons, each designed to meet one of the stated objectives for the unit. The units deal with: introduction to and advantages of EDM, the EDM process, basic components of EDM, reaction between forming tool and workpiece,…

  14. Introduction to Exploring Machines

    ERIC Educational Resources Information Center

    Early Childhood Today, 2006

    2006-01-01

    Young children are fascinated by how things "work." They are at a stage of development where they want to experiment with the many ways to use an object or take things apart and put them back together. In the process of exploring tools and machines, children use the scientific method and problem-solving skills. They observe how things work, wonder…

  15. 8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF THE MACHINE SHOP. BY 1966, THE MACHINE SHOP HANDLED PRIMARILY STAINLESS STEEL COMPONENTS, WHICH WERE SENT TO THE MACHINE SHOP TO BE FORMED INTO THEIR FINAL SHAPES. (7/24/70) - Rocky Flats Plant, General Manufacturing, Support, Records-Central Computing, Southern portion of Plant, Golden, Jefferson County, CO

  16. Induction melter apparatus

    DOEpatents

    Roach, Jay A [Idaho Falls, ID; Richardson, John G [Idaho Falls, ID; Raivo, Brian D [Idaho Falls, ID; Soelberg, Nicholas R [Idaho Falls, ID

    2008-06-17

    Apparatus and methods of operation are provided for a cold-crucible-induction melter for vitrifying waste wherein a single induction power supply may be used to effect a selected thermal distribution by independently energizing at least two inductors. Also, a bottom drain assembly may be heated by an inductor and may include an electrically resistive heater. The bottom drain assembly may be cooled to solidify molten material passing therethrough to prevent discharge of molten material therefrom. Configurations are provided wherein the induction flux skin depth substantially corresponds with the central longitudinal axis of the crucible. Further, the drain tube may be positioned within the induction flux skin depth in relation to material within the crucible or may be substantially aligned with a direction of flow of molten material within the crucible. An improved head design including four shells forming thermal radiation shields and at least two gas-cooled plenums is also disclosed.

  17. Induction heating coupler

    NASA Technical Reports Server (NTRS)

    Fox, Robert L. (Inventor); Copeland, Carl E. (Inventor); Swaim, Robert J. (Inventor); Coultrip, Robert H. (Inventor); Johnston, David F. (Inventor); Phillips, W. Morris (Inventor); Johnson, Samuel D. (Inventor); Dinkins, James R. (Inventor); Buckley, John D. (Inventor)

    1994-01-01

    An induction heating device includes a handle having a hollow interior and two opposite ends, a wrist connected to one end of the handle, a U-shaped pole piece having two spaced apart ends, a tank circuit including an induction coil wrapped around the pole piece and a capacitor connected to the induction coil, a head connected to the wrist and including a housing for receiving the U-shaped pole piece, the two spaced apart ends of the pole piece extending outwardely beyond the housing, and a power source connected to the tank circuit. When the tank circuit is energized and a susceptor is placed in juxtaposition to the ends of the U-shaped pole piece, the susceptor is heated by induction heating due to magnetic flux passing between the two ends of the pole piece.

  18. Enhancing Induction Coil Reliability

    NASA Astrophysics Data System (ADS)

    Kreter, K.; Goldstein, R.; Yakey, C.; Nemkov, V.

    2014-12-01

    In induction hardening, thermal fatigue is one of the main copper failure modes of induction heat treating coils. There have been papers published that describe this failure mode and others that describe some good design practices. The variables previously identified as the sources of thermal fatigue include radiation from the part surface, frequency, current, concentrator losses, water pressure and coil wall thickness. However, there is very little quantitative data on the factors that influence thermal fatigue in induction coils is available in the public domain. By using finite element analysis software this study analyzes the effect of common design variables of inductor cooling, and quantifies the relative importance of these variables. A comprehensive case study for a single shot induction coil with Fluxtrol A concentrator applied is used for the analysis.

  19. Thermal kinetic inductance detector

    DOEpatents

    Cecil, Thomas; Gades, Lisa; Miceli, Antonio; Quaranta, Orlando

    2016-12-20

    A microcalorimeter for radiation detection that uses superconducting kinetic inductance resonators as the thermometers. The detector is frequency-multiplexed which enables detector systems with a large number of pixels.

  20. Intense X-ray machine for penetrating radiography

    NASA Astrophysics Data System (ADS)

    Lucht, Roy A.; Eckhouse, Shimon

    Penetrating radiography has been used for many years in the nuclear weapons research programs. Infrequently penetrating radiography has been used in conventional weapons research programs. For example the Los Alamos PHERMEX machine was used to view uranium rods penetrating steel for the GAU-8 program, and the Ector machine was used to see low density regions in forming metal jets. The armor/anti-armor program at Los Alamos has created a need for an intense flash X-ray machine that can be dedicated to conventional weapons research. The Balanced Technology Initiative, through DARPA, has funded the design and construction of such a machine at Los Alamos. It will be an 8- to 10-MeV diode machine capable of delivering a dose of 500 R at 1 m with a spot size of less than 5 mm. The machine used an 87.5-stage low inductance Marx generator that charges up a 7.4-(Omega), 32-ns water line. The water line is discharged through a self-breakdown oil switch into a 12.4-(Omega) water line that rings up the voltage into the high impendance X-ray diode. A long (233-cm) vacuum drift tube is used to separate the large diameter oil-insulated diode region from the X-ray source area that may be exposed to high overpressures by the explosive experiments. The electron beam is selffocused at the target area using a low pressure background gas.

  1. Linear induction accelerator

    DOEpatents

    Buttram, M.T.; Ginn, J.W.

    1988-06-21

    A linear induction accelerator includes a plurality of adder cavities arranged in a series and provided in a structure which is evacuated so that a vacuum inductance is provided between each adder cavity and the structure. An energy storage system for the adder cavities includes a pulsed current source and a respective plurality of bipolar converting networks connected thereto. The bipolar high-voltage, high-repetition-rate square pulse train sets and resets the cavities. 4 figs.

  2. Induction of the Proepicardium.

    PubMed

    Maya-Ramos, Lisandro; Cleland, James; Bressan, Michael; Mikawa, Takashi

    2013-09-01

    The proepicardium is a transient extracardiac embryonic tissue that gives rise to the epicardium and a number of coronary vascular cell lineages. This important extracardiac tissue develops through multiple steps of inductive events, from specification of multiple cell lineages to morphogenesis. This article will review our current understanding of inductive events involved in patterning of the proepicardium precursor field, specification of cell types within the proepicardium, and their extension and attachment to the heart.

  3. Induction Heating Systems

    NASA Technical Reports Server (NTRS)

    1991-01-01

    Induction heating technology, a magnetic non-deforming process, was developed by Langley researchers to join plastic and composite components in space. Under NASA license, Inductron Corporation uses the process to produce induction heating systems and equipment for numerous applications. The Torobonder, a portable system, comes with a number of interchangeable heads for aircraft repair. Other developments are the E Heating Head, the Toroid Joining Gun, and the Torobrazer. These products perform bonding applications more quickly, safely and efficiently than previous methods.

  4. Induction launcher design considerations

    NASA Technical Reports Server (NTRS)

    Driga, M. D.; Weldon, W. F.

    1989-01-01

    New concepts in the design of induction accelerators and their power supplies for space and military applications are discussed. Particular attention is given to a piecewise-rising-frequency power supply in which each elementary generator (normal compulsator or rising frequency generator) has a different base frequency. A preliminary design of a coaxial induction accelerator for a hypersonic real gas facility is discussed to illustrate the concepts described.

  5. Tattoo machines, needles and utilities.

    PubMed

    Rosenkilde, Frank

    2015-01-01

    Starting out as a professional tattooist back in 1977 in Copenhagen, Denmark, Frank Rosenkilde has personally experienced the remarkable development of tattoo machines, needles and utilities: all the way from home-made equipment to industrial products of substantially improved quality. Machines can be constructed like the traditional dual-coil and single-coil machines or can be e-coil, rotary and hybrid machines, with the more convenient and precise rotary machines being the recent trend. This development has resulted in disposable needles and utilities. Newer machines are more easily kept clean and protected with foil to prevent crosscontaminations and infections. The machines and the tattooists' knowledge and awareness about prevention of infection have developed hand-in-hand. For decades, Frank Rosenkilde has been collecting tattoo machines. Part of his collection is presented here, supplemented by his personal notes. © 2015 S. Karger AG, Basel.

  6. Hinged Shields for Machine Tools

    NASA Technical Reports Server (NTRS)

    Lallande, J. B.; Poland, W. W.; Tull, S.

    1985-01-01

    Flaps guard against flying chips, but fold away for tool setup. Clear plastic shield in position to intercept flying chips from machine tool and retracted to give operator access to workpiece. Machine shops readily make such shields for own use.

  7. Hinged Shields for Machine Tools

    NASA Technical Reports Server (NTRS)

    Lallande, J. B.; Poland, W. W.; Tull, S.

    1985-01-01

    Flaps guard against flying chips, but fold away for tool setup. Clear plastic shield in position to intercept flying chips from machine tool and retracted to give operator access to workpiece. Machine shops readily make such shields for own use.

  8. Induction as Knowledge Integration

    NASA Technical Reports Server (NTRS)

    Smith, Benjamin D.; Rosenbloom, Paul S.

    1996-01-01

    Two key issues for induction algorithms are the accuracy of the learned hypothesis and the computational resources consumed in inducing that hypothesis. One of the most promising ways to improve performance along both dimensions is to make use of additional knowledge. Multi-strategy learning algorithms tackle this problem by employing several strategies for handling different kinds of knowledge in different ways. However, integrating knowledge into an induction algorithm can be difficult when the new knowledge differs significantly from the knowledge the algorithm already uses. In many cases the algorithm must be rewritten. This paper presents Knowledge Integration framework for Induction (KII), a KII, that provides a uniform mechanism for integrating knowledge into induction. In theory, arbitrary knowledge can be integrated with this mechanism, but in practice the knowledge representation language determines both the knowledge that can be integrated, and the costs of integration and induction. By instantiating KII with various set representations, algorithms can be generated at different trade-off points along these dimensions. One instantiation of KII, called RS-KII, is presented that can implement hybrid induction algorithms, depending on which knowledge it utilizes. RS-KII is demonstrated to implement AQ-11, as well as a hybrid algorithm that utilizes a domain theory and noisy examples. Other algorithms are also possible.

  9. Soft Computing Application in Fault Detection of Induction Motor

    SciTech Connect

    Konar, P.; Puhan, P. S.; Chattopadhyay, P. Dr.

    2010-10-26

    The paper investigates the effectiveness of different patter classifier like Feed Forward Back Propagation (FFBPN), Radial Basis Function (RBF) and Support Vector Machine (SVM) for detection of bearing faults in Induction Motor. The steady state motor current with Park's Transformation has been used for discrimination of inner race and outer race bearing defects. The RBF neural network shows very encouraging results for multi-class classification problems and is hoped to set up a base for incipient fault detection of induction motor. SVM is also found to be a very good fault classifier which is highly competitive with RBF.

  10. The Security of Machine Learning

    DTIC Science & Technology

    2008-04-24

    Machine learning has become a fundamental tool for computer security, since it can rapidly evolve to changing and complex situations. That...adaptability is also a vulnerability: attackers can exploit machine learning systems. We present a taxonomy identifying and analyzing attacks against machine ...We use our framework to survey and analyze the literature of attacks against machine learning systems. We also illustrate our taxonomy by showing

  11. Automatically-Programed Machine Tools

    NASA Technical Reports Server (NTRS)

    Purves, L.; Clerman, N.

    1985-01-01

    Software produces cutter location files for numerically-controlled machine tools. APT, acronym for Automatically Programed Tools, is among most widely used software systems for computerized machine tools. APT developed for explicit purpose of providing effective software system for programing NC machine tools. APT system includes specification of APT programing language and language processor, which executes APT statements and generates NC machine-tool motions specified by APT statements.

  12. Automatically-Programed Machine Tools

    NASA Technical Reports Server (NTRS)

    Purves, L.; Clerman, N.

    1985-01-01

    Software produces cutter location files for numerically-controlled machine tools. APT, acronym for Automatically Programed Tools, is among most widely used software systems for computerized machine tools. APT developed for explicit purpose of providing effective software system for programing NC machine tools. APT system includes specification of APT programing language and language processor, which executes APT statements and generates NC machine-tool motions specified by APT statements.

  13. Beam dynamics in the ETA and ATA 10 kA linear induction accelerators: observations and issues

    SciTech Connect

    Briggs, R.J.; Birx, D.L.; Caporaso, G.J.; Fessenden, T.J.; Hester, R.E.; Melendez, R.; Neil, V.K.; Paul, A.C.; Struve, K.W.

    1981-03-06

    The 10 kA ETA and ATA linear induction accelerators are described. Beam instability is the major concern in these high current machines, and the current status of theoretical understanding, and experimental investigations with the 8 cavity ETA, are reviewed. Modifications to the induction cavities are described that have essentially eliminated the transverse resonant modes seen in the ETA.

  14. Machine Shop Fundamentals: Part I.

    ERIC Educational Resources Information Center

    Kelly, Michael G.; And Others

    These instructional materials were developed and designed for secondary and adult limited English proficient students enrolled in machine tool technology courses. Part 1 includes 24 lessons covering introduction, safety and shop rules, basic machine tools, basic machine operations, measurement, basic blueprint reading, layout, and bench tools.…

  15. Isomap based supporting vector machine

    NASA Astrophysics Data System (ADS)

    Liang, W. N.

    2015-12-01

    This research presents a new isomap based supporting vector machine method. Isomap is a dimension reduction method which is able to analyze nonlinear relationship of data on manifolds. Accordingly, support vector machine is established on the isomap manifold to classify given and predict unknown data. A case study of the isomap based supporting vector machine for environmental planning problems is conducted.

  16. The Chainstitch Machine. Module 18.

    ERIC Educational Resources Information Center

    South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

    This module on the chainstitch machine, one in a series dealing with industrial sewing machines, their attachments, and operation, covers one topic: performing special operations on the chainstitch machine. These components are provided: an introduction, directions, an objective, learning activities, student information, a student self-check, and…

  17. Audio-Visual Teaching Machines.

    ERIC Educational Resources Information Center

    Dorsett, Loyd G.

    An audiovisual teaching machine (AVTM) presents programed audio and visual material simultaneously to a student and accepts his response. If his response is correct, the machine proceeds with the lesson; if it is incorrect, the machine so indicates and permits another choice (linear) or automatically presents supplementary material (branching).…

  18. Interferometer systems in machine industry

    NASA Astrophysics Data System (ADS)

    Rzepka, Janusz; Pienkowski, Janusz; Sambor, Slawomir; Budzyn, Grzegorz

    2003-10-01

    In the report the arrangements of laser interferometers for machine history are presented; the laser interferometer LSP30 for investigation of geometry of machine tools, the setup for inspection of ball screw and laser liner for CNC machine. Outstanding feature of the interferometers is the stabilization system of laser frequency using surface stabilized ferroelectric liquid cells (SSFLC).

  19. Comparisons between designs for single-sided linear electric motors: Homopolar synchronous and induction

    NASA Astrophysics Data System (ADS)

    Nondahl, T. A.; Richter, E.

    1980-09-01

    A design study of two types of single sided (with a passive rail) linear electric machine designs, namely homopolar linear synchronous machines (LSM's) and linear induction machines (LIM's), is described. It is assumed the machines provide tractive effort for several types of light rail vehicles and locomotives. These vehicles are wheel supported and require tractive powers ranging from 200 kW to 3735 kW and top speeds ranging from 112 km/hr to 400 km/hr. All designs are made according to specified magnetic and thermal criteria. The LSM advantages are a higher power factor, much greater restoring forces for track misalignments, and less track heating. The LIM advantages are no need to synchronize the excitation frequency precisely to vehicle speed, simpler machine construction, and a more easily anchored track structure. The relative weights of the two machine types vary with excitation frequency and speed; low frequencies and low speeds favor the LSM.

  20. Effect of Machining Velocity in Nanoscale Machining Operations

    NASA Astrophysics Data System (ADS)

    Islam, Sumaiya; Ibrahim, Raafat; Khondoker, Noman

    2015-04-01

    The aim of this study is to investigate the generated forces and deformations of single crystal Cu with (100), (110) and (111) crystallographic orientations at nanoscale machining operation. A nanoindenter equipped with nanoscratching attachment was used for machining operations and in-situ observation of a nano scale groove. As a machining parameter, the machining velocity was varied to measure the normal and cutting forces. At a fixed machining velocity, different levels of normal and cutting forces were generated due to different crystallographic orientations of the specimens. Moreover, after machining operation percentage of elastic recovery was measured and it was found that both the elastic and plastic deformations were responsible for producing a nano scale groove within the range of machining velocities from 250-1000 nm/s.

  1. A Boltzmann machine for the organization of intelligent machines

    NASA Technical Reports Server (NTRS)

    Moed, Michael C.; Saridis, George N.

    1989-01-01

    In the present technological society, there is a major need to build machines that would execute intelligent tasks operating in uncertain environments with minimum interaction with a human operator. Although some designers have built smart robots, utilizing heuristic ideas, there is no systematic approach to design such machines in an engineering manner. Recently, cross-disciplinary research from the fields of computers, systems AI and information theory has served to set the foundations of the emerging area of the design of intelligent machines. Since 1977 Saridis has been developing an approach, defined as Hierarchical Intelligent Control, designed to organize, coordinate and execute anthropomorphic tasks by a machine with minimum interaction with a human operator. This approach utilizes analytical (probabilistic) models to describe and control the various functions of the intelligent machine structured by the intuitively defined principle of Increasing Precision with Decreasing Intelligence (IPDI) (Saridis 1979). This principle, even though resembles the managerial structure of organizational systems (Levis 1988), has been derived on an analytic basis by Saridis (1988). The purpose is to derive analytically a Boltzmann machine suitable for optimal connection of nodes in a neural net (Fahlman, Hinton, Sejnowski, 1985). Then this machine will serve to search for the optimal design of the organization level of an intelligent machine. In order to accomplish this, some mathematical theory of the intelligent machines will be first outlined. Then some definitions of the variables associated with the principle, like machine intelligence, machine knowledge, and precision will be made (Saridis, Valavanis 1988). Then a procedure to establish the Boltzmann machine on an analytic basis will be presented and illustrated by an example in designing the organization level of an Intelligent Machine. A new search technique, the Modified Genetic Algorithm, is presented and proved

  2. Wholly Synthetic Molecular Machines.

    PubMed

    Cheng, Chuyang; Stoddart, J Fraser

    2016-06-17

    The past quarter of a century has witnessed an increasing engagement on the part of physicists and chemists in the design and synthesis of molecular machines de novo. This minireview traces the development of artificial molecular machines from their prototypes in the form of shuttles and switches to their emergence as motors and pumps where supplies of energy in the form of chemical fuel, electrochemical potential and light activation become a minimum requirement for them to function away from equilibrium. The challenge facing this rapidly growing community of scientists and engineers today is one of putting wholly synthetic molecules to work, both individually and as collections. Here, we highlight some of the recent conceptual and practical advances relating to the operation of wholly synthetic rotary and linear motors. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Engineering molecular machines

    NASA Astrophysics Data System (ADS)

    Erman, Burak

    2016-04-01

    Biological molecular motors use chemical energy, mostly in the form of ATP hydrolysis, and convert it to mechanical energy. Correlated thermal fluctuations are essential for the function of a molecular machine and it is the hydrolysis of ATP that modifies the correlated fluctuations of the system. Correlations are consequences of the molecular architecture of the protein. The idea that synthetic molecular machines may be constructed by designing the proper molecular architecture is challenging. In their paper, Sarkar et al (2016 New J. Phys. 18 043006) propose a synthetic molecular motor based on the coarse grained elastic network model of proteins and show by numerical simulations that motor function is realized, ranging from deterministic to thermal, depending on temperature. This work opens up a new range of possibilities of molecular architecture based engine design.

  4. Safety features in anaesthesia machine.

    PubMed

    Subrahmanyam, M; Mohan, S

    2013-09-01

    Anaesthesia is one of the few sub-specialties of medicine, which has quickly adapted technology to improve patient safety. This application of technology can be seen in patient monitoring, advances in anaesthesia machines, intubating devices, ultrasound for visualisation of nerves and vessels, etc., Anaesthesia machines have come a long way in the last 100 years, the improvements being driven both by patient safety as well as functionality and economy of use. Incorporation of safety features in anaesthesia machines and ensuring that a proper check of the machine is done before use on a patient ensures patient safety. This review will trace all the present safety features in the machine and their evolution.

  5. Machining fiber-reinforced composites

    NASA Astrophysics Data System (ADS)

    Komanduri, Ranga

    1993-04-01

    Compared to high tool wear and high costs of tooling of fiber-reinforced composites (FRCs), noncontact material-removal processes offer attractive alternative. Noncontact machining methods can also minimize dust, noise, and extensive plastic deformation and consequent heat generation associated with conventional machining of FRCs, espacially those with an epoxy matrix. The paper describes the principles involved in and the details of machining of FRCs by laser machining, water jet-cutting and abrasive water jet-cutting, and electrical discharge machining of composites, as well as the limitations of each method.

  6. FMS precision machining

    SciTech Connect

    Burnham, M.W.

    1980-01-01

    In evaluating the technical obstacles and accuracy limits to producing a Precision Flexible Manufacturing System, a current system is subjected to an error budget analysis. It is noted that to make complex part geometries with tolerances in the lower thousandths range, machining to tenths is required for process control. Actual parts made to tenths are illustrated, along with a discussion of the requirements for automation and for process control.

  7. Powerful Yet Tiny Machine

    NASA Technical Reports Server (NTRS)

    2004-01-01

    This image taken at JPL shows the Moessbauer spectrometer, an instrument on the Mars Exploration Rover Spirit that detects iron-bearing minerals in martian rocks and soil. Located on the rover's instrument deployment device, or 'arm,' this machine uses two pieces of radioactive cobalt-57, each about the size of pencil erasers, to determine with a high degree of accuracy the composition and abundance of iron-bearing minerals too difficult to detect by other means.

  8. Quantum Virtual Machine (QVM)

    SciTech Connect

    McCaskey, Alexander J.

    2016-11-18

    There is a lack of state-of-the-art HPC simulation tools for simulating general quantum computing. Furthermore, there are no real software tools that integrate current quantum computers into existing classical HPC workflows. This product, the Quantum Virtual Machine (QVM), solves this problem by providing an extensible framework for pluggable virtual, or physical, quantum processing units (QPUs). It enables the execution of low level quantum assembly codes and returns the results of such executions.

  9. Swinging Atwood's Machine

    NASA Astrophysics Data System (ADS)

    Tufillaro, Nicholas B.; Abbott, Tyler A.; Griffiths, David J.

    1984-10-01

    We examine the motion of an Atwood's Machine in which one of the masses is allowed to swing in a plane. Computer studies reveal a rich variety of trajectories. The orbits are classified (bounded, periodic, singular, and terminating), and formulas for the critical mass ratios are developed. Perturbative techniques yield good approximations to the computer-generated trajectories. The model constitutes a simple example of a nonlinear dynamical system with two degrees of freedom.

  10. Making Atwood's machine ``work''

    NASA Astrophysics Data System (ADS)

    Johnson, Gordon O.

    2001-03-01

    PASCO scientific's Smart Pulley™, a lightweight, low-friction pulley and a photogate, begs to be used as an Atwood's machine to determine the acceleration of gravity, g. Unfortunately ignoring the mass and friction of the pulley results in poor values of g. In this paper a procedure is outlined that includes the effects of the pulley's inertia and friction. As a result, the value of g may be determined to an accuracy of 0.1%.

  11. Evolution of Replication Machines

    PubMed Central

    Yao, Nina Y.; O'Donnell, Mike E.

    2016-01-01

    The machines that decode and regulate genetic information require the translation, transcription and replication pathways essential to all living cells. Thus, it might be expected that all cells share the same basic machinery for these pathways that were inherited from the primordial ancestor cell from which they evolved. A clear example of this is found in the translation machinery that converts RNA sequence to protein. The translation process requires numerous structural and catalytic RNAs and proteins, the central factors of which are homologous in all three domains of life, bacteria, archaea and eukarya. Likewise, the central actor in transcription, RNA polymerase, shows homology among the catalytic subunits in bacteria, archaea and eukarya. In contrast, while some “gears” of the genome replication machinery are homologous in all domains of life, most components of the replication machine appear to be unrelated between bacteria and those of archaea and eukarya. This review will compare and contrast the central proteins of the “replisome” machines that duplicate DNA in bacteria, archaea and eukarya, with an eye to understanding the issues surrounding the evolution of the DNA replication apparatus. PMID:27160337

  12. Architectures for intelligent machines

    NASA Technical Reports Server (NTRS)

    Saridis, George N.

    1991-01-01

    The theory of intelligent machines has been recently reformulated to incorporate new architectures that are using neural and Petri nets. The analytic functions of an intelligent machine are implemented by intelligent controls, using entropy as a measure. The resulting hierarchical control structure is based on the principle of increasing precision with decreasing intelligence. Each of the three levels of the intelligent control is using different architectures, in order to satisfy the requirements of the principle: the organization level is moduled after a Boltzmann machine for abstract reasoning, task planning and decision making; the coordination level is composed of a number of Petri net transducers supervised, for command exchange, by a dispatcher, which also serves as an interface to the organization level; the execution level, include the sensory, planning for navigation and control hardware which interacts one-to-one with the appropriate coordinators, while a VME bus provides a channel for database exchange among the several devices. This system is currently implemented on a robotic transporter, designed for space construction at the CIRSSE laboratories at the Rensselaer Polytechnic Institute. The progress of its development is reported.

  13. Universal Memcomputing Machines.

    PubMed

    Traversa, Fabio Lorenzo; Di Ventra, Massimiliano

    2015-11-01

    We introduce the notion of universal memcomputing machines (UMMs): a class of brain-inspired general-purpose computing machines based on systems with memory, whereby processing and storing of information occur on the same physical location. We analytically prove that the memory properties of UMMs endow them with universal computing power (they are Turing-complete), intrinsic parallelism, functional polymorphism, and information overhead, namely, their collective states can support exponential data compression directly in memory. We also demonstrate that a UMM has the same computational power as a nondeterministic Turing machine, namely, it can solve nondeterministic polynomial (NP)-complete problems in polynomial time. However, by virtue of its information overhead, a UMM needs only an amount of memory cells (memprocessors) that grows polynomially with the problem size. As an example, we provide the polynomial-time solution of the subset-sum problem and a simple hardware implementation of the same. Even though these results do not prove the statement NP = P within the Turing paradigm, the practical realization of these UMMs would represent a paradigm shift from the present von Neumann architectures, bringing us closer to brain-like neural computation.

  14. Machine Learning in Medicine.

    PubMed

    Deo, Rahul C

    2015-11-17

    Spurred by advances in processing power, memory, storage, and an unprecedented wealth of data, computers are being asked to tackle increasingly complex learning tasks, often with astonishing success. Computers have now mastered a popular variant of poker, learned the laws of physics from experimental data, and become experts in video games - tasks that would have been deemed impossible not too long ago. In parallel, the number of companies centered on applying complex data analysis to varying industries has exploded, and it is thus unsurprising that some analytic companies are turning attention to problems in health care. The purpose of this review is to explore what problems in medicine might benefit from such learning approaches and use examples from the literature to introduce basic concepts in machine learning. It is important to note that seemingly large enough medical data sets and adequate learning algorithms have been available for many decades, and yet, although there are thousands of papers applying machine learning algorithms to medical data, very few have contributed meaningfully to clinical care. This lack of impact stands in stark contrast to the enormous relevance of machine learning to many other industries. Thus, part of my effort will be to identify what obstacles there may be to changing the practice of medicine through statistical learning approaches, and discuss how these might be overcome.

  15. Making molecular machines work.

    PubMed

    Browne, Wesley R; Feringa, Ben L

    2006-10-01

    In this review we chart recent advances in what is at once an old and very new field of endeavour--the achievement of control of motion at the molecular level including solid-state and surface-mounted rotors, and its natural progression to the development of synthetic molecular machines. Besides a discussion of design principles used to control linear and rotary motion in such molecular systems, this review will address the advances towards the construction of synthetic machines that can perform useful functions. Approaches taken by several research groups to construct wholly synthetic molecular machines and devices are compared. This will be illustrated with molecular rotors, elevators, valves, transporters, muscles and other motor functions used to develop smart materials. The demonstration of molecular machinery is highlighted through recent examples of systems capable of effecting macroscopic movement through concerted molecular motion. Several approaches to illustrate how molecular motor systems have been used to accomplish work are discussed. We will conclude with prospects for future developments in this exciting field of nanotechnology.

  16. CNC electrical discharge machining centers

    SciTech Connect

    Jaggars, S.R.

    1991-10-01

    Computer numerical control (CNC) electrical discharge machining (EDM) centers were investigated to evaluate the application and cost effectiveness of establishing this capability at Allied-Signal Inc., Kansas City Division (KCD). In line with this investigation, metal samples were designed, prepared, and machined on an existing 15-year-old EDM machine and on two current technology CNC EDM machining centers at outside vendors. The results were recorded and evaluated. The study revealed that CNC EDM centers are a capability that should be established at KCD. From the information gained, a machine specification was written and a shop was purchased and installed in the Engineering Shop. The older machine was exchanged for a new model. Additional machines were installed in the Tool Design and Fabrication and Precision Microfinishing departments. The Engineering Shop machine will be principally used for the following purposes: producing deep cavities in small corner radii, machining simulated casting models, machining difficult-to-machine materials, and polishing difficult-to-hand polish mold cavities. 2 refs., 18 figs., 3 tabs.

  17. High Performance Variable Speed Drive System and Generating System with Doubly Fed Machines

    NASA Astrophysics Data System (ADS)

    Tang, Yifan

    Doubly fed machines are another alternative for variable speed drive systems. The doubly fed machines, including doubly fed induction machine, self-cascaded induction machine and doubly excited brushless reluctance machine, have several attractive advantages for variable speed drive applications, the most important one being the significant cost reduction with a reduced power converter rating. With a better understanding, improved machine design, flexible power converters and innovated controllers, the doubly fed machines could favorably compete for many applications, which may also include variable speed power generations. The goal of this research is to enhance the attractiveness of the doubly fed machines for both variable speed drive and variable speed generator applications. Recognizing that wind power is one of the favorable clean, renewable energy sources that can contribute to the solution to the energy and environment dilemma, a novel variable-speed constant-frequency wind power generating system is proposed. By variable speed operation, energy capturing capability of the wind turbine is improved. The improvement can be further enhanced by effectively utilizing the doubly excited brushless reluctance machine in slip power recovery configuration. For the doubly fed machines, a stator flux two -axis dynamic model is established, based on which a flexible active and reactive power control strategy can be developed. High performance operation of the drive and generating systems is obtained through advanced control methods, including stator field orientation control, fuzzy logic control and adaptive fuzzy control. System studies are pursued through unified modeling, computer simulation, stability analysis and power flow analysis of the complete drive system or generating system with the machine, the converter and the control. Laboratory implementations and tested results with a digital signal processor system are also presented.

  18. Wrapper Induction Software

    SciTech Connect

    2011-08-18

    Wrapper Induction is a software package that allows for unsupervised, semi-supervised, and manual extraction of social media data independent of language or site architecture. A large range of blog formats is available to individuals as means of publishing data to the internet. Blogs are a source of rich information for analysts. With a growing volume of information and blog engines, there is an increased need for automatic or semi-automatic extraction of that data for processing to help deliver results to analysts. Wrapper Induction is designed to automatically or semi-automatically create a template that can be used to harvest blog data from websites. Blogs are in a variety of formats and languages. Wrapper Induction creates a template and extracts blog data in a way that is independent of a specified blog format or language.

  19. Inductive Queries for a Drug Designing Robot Scientist

    NASA Astrophysics Data System (ADS)

    King, Ross D.; Schierz, Amanda; Clare, Amanda; Rowland, Jem; Sparkes, Andrew; Nijssen, Siegfried; Ramon, Jan

    It is increasingly clear that machine learning algorithms need to be integrated in an iterative scientific discovery loop, in which data is queried repeatedly by means of inductive queries and where the computer provides guidance to the experiments that are being performed. In this chapter, we summarise several key challenges in achieving this integration of machine learning and data mining algorithms in methods for the discovery of Quantitative Structure Activity Relationships (QSARs). We introduce the concept of a robot scientist, in which all steps of the discovery process are automated; we discuss the representation of molecular data such that knowledge discovery tools can analyse it, and we discuss the adaptation of machine learning and data mining algorithms to guide QSAR experiments.

  20. Inductive dielectric analyzer

    NASA Astrophysics Data System (ADS)

    Agranovich, Daniel; Polygalov, Eugene; Popov, Ivan; Ben Ishai, Paul; Feldman, Yuri

    2017-03-01

    One of the approaches to bypass the problem of electrode polarization in dielectric measurements is the free electrode method. The advantage of this technique is that, the probing electric field in the material is not supplied by contact electrodes, but rather by electromagnetic induction. We have designed an inductive dielectric analyzer based on a sensor comprising two concentric toroidal coils. In this work, we present an analytic derivation of the relationship between the impedance measured by the sensor and the complex dielectric permittivity of the sample. The obtained relationship was successfully employed to measure the dielectric permittivity and conductivity of various alcohols and aqueous salt solutions.