Science.gov

Sample records for multisite spectroscopic observations

  1. Spectroscopic Observations of Merging Galaxies

    NASA Astrophysics Data System (ADS)

    Donzelli, C. J.; Pastoriza, M. G.

    2000-07-01

    In this paper we describe the spectroscopic and infrared properties of a sample of 25 merging galaxy pairs, selected from the catalog of Arp & Madore, and we compare them with those observed in a similar sample of interacting galaxies (Donzelli & Pastoriza). It is noted that mergers as well as interacting systems comprise a wide range of spectral types, going from those corresponding to well-evolved stellar populations (older than 200 Myr) to those that show clear signatures of H II regions with stellar populations younger than 8 Myr. However, merger galaxies show on average more excited spectra than interacting pairs, which could be attributed to lower gas metallicity. From the emission lines we also found that merging systems show on average higher (about a factor of 2) star formation rates than interacting galaxies. Classical diagnostic diagrams show that only three of 50 of the galaxies (6%) present some form of nuclear activity: two Seyfert galaxies and one LINER. However, through a detailed analysis of the pure emission-line spectra, we conclude that this fraction may raise up to 23% of the mergers if we consider that some galaxies host a low-luminosity active nucleus surrounded by strong star-forming regions. This latter assumption is also supported by the infrared colors of the galaxies. Regarding to the total infrared luminosities, the merging galaxies show on average an IR luminosity, log(Lir)=10.7, lower than that of interacting systems, log(Lir)=10.9. We find that only three mergers of the sample (12%) can be classified as luminous infrared galaxies, while this fraction increases to 24% in the interacting sample. Based on observations made at CASLEO. Complejo Astronómico El Leoncito is operated under agreement between the Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina and the National Universities of La Plata, Córdoba and San Juan.

  2. Spectroscopic observations of ASASSN-15bp

    NASA Astrophysics Data System (ADS)

    Williams, S. C.; Darnley, M. J.; Bode, M. F.; Copperwheat, C. M.

    2015-01-01

    We report spectroscopic observations of the optical transient ASASSN-15bp (ATel #6981) taken on 2015 January 25.31 UT using the FRODOSpec spectrograph (Barnsley et al. 2012) on the Liverpool Telescope (Steele et al. 2004).

  3. Spectroscopic observation of the rotational Doppler effect.

    PubMed

    Barreiro, S; Tabosa, J W R; Failache, H; Lezama, A

    2006-09-15

    We report on the first spectroscopic observation of the rotational Doppler shift associated with light beams carrying orbital angular momentum. The effect is evidenced as the broadening of a Hanle electromagnetically induced transparency coherence resonance on Rb vapor when the two incident Laguerre-Gaussian laser beams have opposite topological charges. The observations closely agree with theoretical predictions.

  4. AstroNet: A Tool Set for Simultaneous, Multi-Site Observations of Astronomical Objects

    NASA Technical Reports Server (NTRS)

    Chakrabarti, Supriya

    1995-01-01

    Earth-based, fully automatic "robotic" telescopes have been in routine operation for a number of years. As their number grows and their distribution becomes global, increasing attention is being given to forming networks of various sorts that will allow them, as a group, to make observations 24 hours a day in both hemispheres. We have suggested that telescopes based in space be part of this network. We further suggested that any telescope on this network be capable of asking, almost in real time, that other robotic telescopes perform support observations for them. When a target of opportunity required support observations, the system would determine which telescope(s) in the network would be most appropriate to make the observations and formulate a request to do so. Because the network would be comprised of telescopes located in widely distributed regions, this system would guarantee continuity of observations This report summarizes our efforts under this contract. We proposed to develop a set of data collection and display tools to aid simultaneous observation of astronomical targets from a number of observing sites. We planned to demonstrate the usefulness of this toolset for simultaneous multi-site observation of astronomical targets. Possible candidates or the proposed demonstration included the Extreme Ultraviolet Explorer (EUVE), International Ultraviolet Explorer (IUE), and ALEXIS, sounding rocket experiments. Ground-based observatories operated by the University of California, Berkeley, the Jet Propulsion Laboratory, and Fairborn Observatory in Mesa, Arizona were to be used to demonstrate the proposed concept. Although the demonstration was to have involved astronomical investigations, the tools were to have been applicable to a large number of scientific disciplines. The software tools and systems developed as a result of the work were to have been made available to the scientific community.

  5. Spectroscopic observations of cool degenerate star candidates

    NASA Technical Reports Server (NTRS)

    Hintzen, P.

    1986-01-01

    Spectroscopic observations are reported for 23 Luyten Half-Second degenerate star candidates and for 13 Luyten-Palomar common proper-motion pairs containing possible degenerate star components. Twenty-five degenerate stars are identified, 20 of which lack previous spectroscopy. Most of these stars are cool - Luyten color class g or later. One star, LP 77-57, shows broad continuum depressions similar to those in LHS 1126, which Liebert and Dahn attributed to pressure-shifted C2. A second degenerate star, LHS 290, exhibits apparent strong Swan bands which are blueshifted about 75 A. Further observations, including polarimetry and photometry, are required to appraise the spectroscopic peculiarities of these stars. Finally, five cool, sharp-lined DA white dwarfs have been observed to detect lines of metals and to determine line strengths. None of these DAs show signs of Mg b or the G band, and four show no evidence of Ca II K. The attempt to detect Ca MI in the fifth star, G199-71, was inconclusive.

  6. Spectroscopic observations of HZ Herculis. II

    NASA Technical Reports Server (NTRS)

    Bopp, B. W.; Grupsmith, G.; Mcmillan, R. S.; Vanden Bout, P. A.; Wootten, H. A.

    1973-01-01

    Preliminary results from an extensive series of spectroscopic observations of the HZ Her optical counterpart of the eclipsing, pulsating X-ray binary Her X-1. Spectrograms with a dispersion of 30 A/mm reveal a spectral type as late as F5 near minimum in the light curve with the G-band and metallic lines present. Narrow Fe lines show that HZ Her is not a rapid rotator. Low-dispersion (115 A/mm) spectra, obtained with 10-minute time resolution, reveal rapid (10-min) variations in the 4640 N III emission and in the 4471 He I absorbtion features. The H-beta absorption is variable in equivalent width, and shows evidence of being partially filled with emission.

  7. Using a Two-Staged Propensity Score Matching Strategy and Multilevel Modeling to Estimate Treatment Effects in a Multisite Observational Study

    ERIC Educational Resources Information Center

    Rickles, Jordan H.

    2012-01-01

    The study is designed to demonstrate and test the utility of the proposed two-stage matching method compared to other analytic methods traditionally employed for multisite observational studies. More specifically, the study addresses the following research questions: (1) How do different specifications of the matching method influence covariate…

  8. Asiago spectroscopic observation of four transients

    NASA Astrophysics Data System (ADS)

    Ochner, P.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Pastorello, A.; Tartaglia, L.; Terreran, G.; Tomasella, L.; Turatto, M.

    2015-08-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of PSN J23164332+3359476 in UGC 12474, discovered by C. Emmanouilidi; PS15bom in SDSS J232637.06-001723.0, discovered by the PS1 Science Consortium (Atel #7864); PSN J02484234+1418454 in UGC 2282, discovered by S. Leonini, M. Conti, P. Rosi, L.M. Tinjaca Ramirez and G. Guerrini of the Italian Supernovae Search Project (ISSP); and ASASSN-15mr, discovered by the All Sky Automated Survey for SuperNovae (ASAS-SN; ATel #7811).

  9. GROUND-BASED MULTISITE OBSERVATIONS OF TWO TRANSITS OF HD 80606b

    SciTech Connect

    Shporer, A.; Winn, J. N.; Dreizler, S.; Colon, K. D.; Wood-Vasey, W. M.; Cerutti, S.; Coban, L.; Costello, K.; Choi, P. I.; Morley, C.; Adams, E.; Moutou, C.; Welsh, W. F.; Pollaco, D.; Barros, S. C. C.; Starkey, D.; Bouchy, F.; DIaz, R. F.; Cabrera-Lavers, A.; Deeg, H.

    2010-10-10

    We present ground-based optical observations of the 2009 September and 2010 January transits of HD 80606b. Based on three partial light curves of the 2009 September event, we derive a midtransit time of T{sub c} [HJD] = 2455099.196 {+-} 0.026, which is about 1{sigma} away from the previously predicted time. We observed the 2010 January event from nine different locations, with most phases of the transit being observed by at least three different teams. We determine a midtransit time of T{sub c} [HJD] = 2455210.6502 {+-} 0.0064, which is within 1.3{sigma} of the time derived from a Spitzer observation of the same event.

  10. A Two-Stage Propensity Score Matching Strategy for Treatment Effect Estimation in a Multisite Observational Study

    ERIC Educational Resources Information Center

    Rickles, Jordan H.; Seltzer, Michael

    2014-01-01

    When nonrandom treatments occur across sites, within-site matching (WM) is often desirable. This approach, however, can significantly reduce treatment group sample size and exclude substantively important subgroups. To limit these drawbacks, we extend a matching approach developed by Stuart and Rubin to a multisite study. We demonstrate the…

  11. Using and Experiencing the Academic Library: A Multisite Observational Study of Space and Place

    ERIC Educational Resources Information Center

    May, Francine; Swabey, Alice

    2015-01-01

    This study examines how students are using academic library spaces and the role these spaces are playing in the campus community. Data were collected on five campuses (two community colleges, two undergraduate universities, and one technical institute) via observational seating sweeps and questionnaires. The study found remarkably similar usage…

  12. A multi-site intercomparison of integrated water vapour observations for climate change analysis

    NASA Astrophysics Data System (ADS)

    Van Malderen, R.; Brenot, H.; Pottiaux, E.; Beirle, S.; Hermans, C.; De Mazière, M.; Wagner, T.; De Backer, H.; Bruyninx, C.

    2014-08-01

    Water vapour plays a dominant role in the climate change debate. However, observing water vapour over a climatological time period in a consistent and homogeneous manner is challenging. On one hand, networks of ground-based instruments able to retrieve homogeneous integrated water vapour (IWV) data sets are being set up. Typical examples are Global Navigation Satellite System (GNSS) observation networks such as the International GNSS Service (IGS), with continuous GPS (Global Positioning System) observations spanning over the last 15+ years, and the AErosol RObotic NETwork (AERONET), providing long-term observations performed with standardized and well-calibrated sun photometers. On the other hand, satellite-based measurements of IWV already have a time span of over 10 years (e.g. AIRS) or are being merged to create long-term time series (e.g. GOME, SCIAMACHY, and GOME-2). This study performs an intercomparison of IWV measurements from satellite devices (in the visible, GOME/SCIAMACHY/GOME-2, and in the thermal infrared, AIRS), in situ measurements (radiosondes) and ground-based instruments (GPS, sun photometer), to assess their use in water vapour trends analysis. To this end, we selected 28 sites world-wide for which GPS observations can directly be compared with coincident satellite IWV observations, together with sun photometer and/or radiosonde measurements. The mean biases of the different techniques compared to the GPS estimates vary only between -0.3 to 0.5 mm of IWV. Nevertheless these small biases are accompanied by large standard deviations (SD), especially for the satellite instruments. In particular, we analysed the impact of clouds on the IWV agreement. The influence of specific issues for each instrument on the intercomparison is also investigated (e.g. the distance between the satellite ground pixel centre and the co-located ground-based station, the satellite scan angle, daytime/nighttime differences). Furthermore, we checked if the properties of

  13. Seasonal Variation of Methane Emissions in California's Urban and Rural Regions Using Multi-site Observations

    NASA Astrophysics Data System (ADS)

    Jeong, S.; Hsu, Y.; Andrews, A. E.; Bianco, L.; Newman, S.; Cui, X.; Bagley, J.; Graven, H. D.; Salameh, P.; Sloop, C.; LaFranchi, B.; Michelsen, H. A.; Bambha, R.; Weiss, R. F.; Keeling, R. F.; Fischer, M. L.

    2014-12-01

    California's commitment (Assembly Bill 32) to reduce total greenhouse gas (GHG) emissions to 1990 levels by 2020 requires quantification of current GHG emissions. We present seasonal variation of California's total CH4 emissions for summer 2013 - spring 2014, using data from a dozen sites covering urban and rural areas of California that include South Coast Air Basin (SoCAB), Central Valley, and San Francisco Bay Area. We apply a Bayesian inverse model to estimate CH4 emissions from discrete regions of California and source sectors by combining atmospheric measurements, upstream background, updated high-resolution prior emission maps developed for California, and predicted atmospheric transport from WRF-STILT. We quantify site-specific model-measurement uncertainties due to transport using simulated and observed meteorology, background estimated from oceanic and aircraft observations, and the prior emissions. In particular, we evaluate predicted transport variables in WRF with networks of surface and upper air observations. Preliminary inversion results during summer of 2013 suggest that state total CH4 emissions are 1.2 - 1.7 times higher than the current CARB inventory. Here, we extend and improve upon earlier analyses to provide a full seasonal cycle of CH4 emissions across all major urban and rural regions in California.

  14. Development and initial validation of the Observer-Rated Housing Quality Scale (OHQS) in a multisite trial of housing first.

    PubMed

    Adair, Carol E; Kopp, Brianna; Lavoie, Jennifer; Distasio, Jino; Hwang, Stephen W; Watson, Aimee; Veldhuizen, Scott; Chislett, Katherine; Voronka, Jijian; Ahmad, Muznah; Ahmed, Naveed; Goering, Paula

    2014-04-01

    Quality of housing has been shown to be related to health outcomes, including mental health and well-being, yet "objective" or observer-rated housing quality is rarely measured in housing intervention research. This may be due to a lack of standardized, reliable, and valid housing quality instruments. The objective of this research was to develop and validate the Observer-Rated Housing Quality Scale (OHQS) for use in a multisite trial of a "housing first" intervention for homeless individuals with mental illness. A list of 79 housing unit, building, and neighborhood characteristics was generated from a review of the relevant literature and three focus groups with consumers and housing service providers. The characteristics were then ranked by 47 researchers, consumers, and service providers on perceived importance, generalizability, universality of value, and evidence base. Items were then drafted, scaled (five points, half values allowed), and pretested in seven housing units and with seven raters using cognitive interviewing techniques. The draft scale was piloted in 55 housing units in Toronto and Winnipeg, Canada. Items were rated independently in each unit by two trained research assistants and a housing expert. Data were analyzed using classical psychometric approaches and intraclass correlation coefficients (ICC) for inter-rater reliability. The draft scale consisted of 34 items assessing three domains: the unit, the building, and the neighborhood. Five of 18 unit items and 3 of 7 building items displayed ceiling or floor effects and were adjusted accordingly. Internal consistency was very good (Cronbach's alpha = 0.90 for the unit items, 0.80 for the building items, and 0.92 total (unit and building)). Percent agreement ranged from 89 to 100 % within one response scale value and 67 to 91 % within one half scale value. Inter-rater reliability was also good (ICCs were 0.87 for the unit, 0.85 for the building, and 0.93 for the total scale). Three

  15. Irradiation effects on canvas oil painting: Spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Manea, Mihaela Maria; Negut, C. D.; Stanculescu, Ioana Rodica; Ponta, C. C.

    2012-10-01

    "Winter" oil painting, by Romanian contemporary artist George Alexandrescu was used as experimental model for the substantiation of gamma radiation treatment, as the best choice to stop the biological attack of paintings. In this purpose, spectroscopic and colorimetric methods were used to analyse in situ, non-destructively and non-contact, the experimental model before and after 60Co gamma irradiation. Chemical structure and colour changes were monitored by FTIR, FT-Raman and Vis reflectance spectroscopy. Negligible Infrared spectral transformations have been observed after irradiation. Furthermore, it was found that gamma irradiation did not induce any significant colour alterations. Insignificant structural and colour changes observed, recommend the use of gamma irradiation in the disinfection of oil paintings.

  16. Life after eruption - I. Spectroscopic observations of 10 nova candidates

    NASA Astrophysics Data System (ADS)

    Tappert, C.; Ederoclite, A.; Mennickent, R. E.; Schmidtobreick, L.; Vogt, N.

    2012-07-01

    We have started a project to investigate the connection of post-novae with the population of cataclysmic variables (CVs). Our first steps in this concern improving the sample of known post-novae and their properties. Here we present the recovery and/or confirmation of the old novae MT Cen, V812 Cen, V655 CrA, IL Nor, V2109 Oph, V909 Sgr, V2572 Sgr and V728 Sco. Principal photometric and spectroscopic properties of these systems are discussed. We find that V909 Sgr is a probable magnetic CV, and that V728 Sco is a high-inclination system. We furthermore suggest that the two candidate novae V734 Sco and V1310 Sgr have been misclassified and instead are Mira variables. Based on observations with ESO telescopes, proposal numbers 083.D-0158, 086.D-0428 and 087.D-0323.

  17. Constructing Counterfactuals in a Multisite Observational Study Using Propensity Score Matching and Multilevel Modeling: An Empirical Example Looking at the Effect of 8th Grade Algebra across Students and Schools

    ERIC Educational Resources Information Center

    Rickles, Jordan H.

    2011-01-01

    This study seeks to demonstrate a method for treatment effect estimation in a multisite observational study where the treatment is highly selective and the assignment mechanism varies across sites. The method is demonstrated by addressing three primary research questions about the effect of 8th grade algebra: (1) For students who take algebra in…

  18. Spectroscopic and video observations of fullerene production arcs

    SciTech Connect

    Lorents, D.C.; Stalder, K.R.; Keegan, D.M.; Ruoff, R.S.; Malhotra, R.M.

    1993-12-01

    Spatially resolved spectroscopic studies of a carbon arc operating under fullerene production conditions have been made across the visible wavelength range using an imaging Optical Multichannel Analyzer. C{sub 2} Swan bands are observed to be the major visible emissions although strong CI and CII as well as He I atomic lines are also observed. Video and photographic studies of the arc characteristics show the Swan-band emissions to be concentrated most intensely near the anode but also to appear strongly in regions well outside the electrode gap region. Vibrational and rotational temperatures of these bands provide information on the temperatures in various regions of the arc. The characteristic spatial structure of the arcs observed in the Swan-band light suggests that they are excited by electrons whose trajectories are controlled by the local electric and magnetic fields. The arc exhibits complex and interesting temporal behavior that has been observed with a video camera using short exposure times. Video film taken through a Swan-band filter clearly shows the dominant spatial features of the C{sub 2} emissions.

  19. LBT/LUCI Spectroscopic Observations of z≃7 Galaxies

    NASA Astrophysics Data System (ADS)

    Bian, Fuyan; Stark, Daniel P.; Fan, Xiaohui; Jiang, Linhua; Clément, Benjamin; Egami, Eiichi; Frye, Brenda; Green, Richard F.; McGreer, Ian D.; Cai, Zheng

    2015-06-01

    We present deep near-infrared spectroscopic observations of 13 luminous z≃ 7 Lyman break galaxies (LBGs) ({{M}UV}≃ -21) and a z≃ 9.6 lensed LBG candidate, MACS1149-JD1, using the LBT/LUCI spectrograph in the multi-object mode and long-slit mode, respectively. The z˜ 7 galaxies are selected in one of the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey/WIDE survey observations, the UKIRT Infrared Deep Sky Survey Ultra Deep Survey field, and MACS1159-JD1 is selected from the Cluster Lensing And Supernova survey with Hubble survey observations. With ˜4-5 hr integrations, the LBT spectra are sensitive to Lyα emission, with rest-frame equivalent width greater than 55 Å (E{{W}0}\\gt 55 Å) at z˜ 7 and 90 Å (E{{W}0}\\gt 90 Å) at z˜ 9.5. No Lyα emission is observed in any of the z≃ 7 LBGs. After correcting the spectroscopic incompleteness, our measurements place an upper limit on the Lyα emission fraction of {{X}Lyα }(E{{W}0}\\gt 55 { {\\mathring{{A}} }},z≃ 7)\\lt 9.8% in luminous LBGs at z≃ 7. This result is consistent with the lack of Lyα emission in z\\gt 7 LBGs in previous studies. Together with other measurements of the Lyα emission fraction in LBGs at z≃ 7, this study puts a strong constraint on the fraction of luminous z≃ 7 LBGs with large EW Lyα, {{X}Lyα }(E{{W}0}\\gt 55 { {\\mathring{{A}} }},z≃ 7)=2.6-2.6+3.2%. We estimate the expected Lyα emission fraction at z≃ 7 by extrapolating the evolution of the fraction at low redshifts and find that the observed Lyα emission fraction is lower than the expected Lyα emission fraction at the 89% significance level, consistent with expectations if Lyα emission in z≃ 7 LBGs has been suppressed by neutral hydrogen in the intergalactic medium or optically thick absorbers around the galaxies. We do not find any strong Lyα emission feature at the redshift range of z ≃ 7.3-9.7 in the MACSJ1159-JD1 spectrum, either. This is consistent with the conclusion that Lyα emission in

  20. Spectroscopic Observations of the Star Formation Regions in Nearby Galaxies

    NASA Astrophysics Data System (ADS)

    Kong, X.; Lin, L.; Li, J. R.; Zhou, X.; Zou, H.; Li, H. Y.; Chen, F. Z.; Du, W.; Fan, Z.; Mao, Y. W.; Wang, J.; Zhu, Y. N.; Zhou, Z. M.

    2014-01-01

    During the late 1990s and the first decade of the 21st century, the 8˜10 m scale ground-based telescopes are helping astronomers learn much more about how galaxies develop. The existing 2˜4 m scale telescopes become less important for astrophysical researches. To use the existing 2˜4 m scale telescopes to address important issues in cosmology and extragalactic and galactic astronomy, we have to consider very carefully which kind of things we can do, and which we can not. For this reason, the Time Allocation Committee (TAC) of the National Astronomical Observatories of China (NAOC) 2.16 m telescope decides to support some key projects since 2013. Nearby galaxies supply us with the opportunity to study galaxy dynamics and star formation on large scales, yet are close enough to reveal the details. Star formation regions in nearby galaxies provide an excellent laboratory to study the star formation processes, the evolution of massive stars, and the properties of the surrounding interstellar medium. A wealth of information can be obtained from the spectral analysis of the bright emission lines and the stellar continuum. Considering these, we proposed a long-term project ``Spectroscopic Observations of the Star Formation Regions in Nearby Galaxies'', and it becomes the key project of the NAOC 2.16 m telescope since 2013, supported with 30 dark/grey nights per year. The primary goal of this project is to observe the spectroscopy of star formation regions in 20 nearby galaxies, with the NAOC 2.16 m telescope and the Hectospec/MMT (Multiple Mirror Telescope) multifiber spectrograph by Telescope Access Program (TAP). With the spectra of a large sample of star formation regions, combining multi-wavelength data from UV to IR, we can investigate, understand, and quantify the nature of the deviation from the starbursts' IRX-β (the IR/UV ratio ``IRX'' versus the UV color ``β'') correlation. It will be important for a better understanding of the interaction of dust and

  1. Using a Two-Stage Propensity Score Matching Strategy and Multilevel Modeling to Estimate Treatment Effects in a Multisite Observational Study

    ERIC Educational Resources Information Center

    Rickles, Jordan Harry

    2012-01-01

    In this study I present, demonstrate, and test a method that extends the Stuart and Rubin (2008) multiple control group matching strategy to a multisite setting. Three primary phases define the proposed method: (1) a design phase, in which one uses a two-stage matching strategy to construct treatment and control groups that are well balanced along…

  2. Spectroscopic Observation of Chemical Interaction Between Impact-induced Vapor Clouds and the Ambient Atmosphere

    NASA Technical Reports Server (NTRS)

    Sugita, S.; Heineck, J. T.; Schultz, P. H.

    2000-01-01

    Chemical reactions within impact-induced vapor clouds were observed in laboratory experiments using a spectroscopic method. The results indicate that projectile-derived carbon-rich vapor reacts intensively with atmospheric nitrogen.

  3. Estimating CH4 and CO Emissions in California's Urban and Rural Regions Using Multi-site Observations

    NASA Astrophysics Data System (ADS)

    Jeong, S.; Andrews, A. E.; Bianco, L.; Graven, H. D.; Hsu, Y.; Newman, S.; Novakovskaia, E.; Vaca, P.; Salameh, P.; Sloop, C.; Weiss, R. F.; Keeling, R. F.; Fischer, M. L.

    2013-12-01

    California's commitment (Assembly Bill 32) to reduce total greenhouse gas (GHG) emissions to 1990 levels by 2020 (~20% reduction) requires quantification of current GHG emissions. We will present atmospheric inversion estimates of California's total CH4 emissions for summer 2013, using data from multiple sites covering urban and rural areas of California's South Coast Air Basin (SoCAB), Central Valley, and San Francisco Bay Area. We will also use measured CO from two tall-tower sites (Central Valley and SoCAB) to quantify CO emissions as well as to evaluate atmospheric transport. We use Bayesian inverse modeling to estimate the CH4 and CO emissions from discrete regions of California by combining the atmospheric measurements, upstream background, high-resolution prior emission maps, and predicted atmospheric transport from WRF-STILT. We quantify site-specific model-measurement uncertainties due to transport using meteorological data from a network of atmospheric profilers and in-situ sensors, due to background using oceanic and aircraft observations, and the prior emissions. To reduce the uncertainty in transport, we assimilate available meteorological measurements from surface and upper air stations, and wind profilers into the WRF model. Preliminary inversion results during September 2010 - June 2011 and summer of 2012 suggest that state total CH4 emissions are 1.2 - 1.8 times higher than the current CARB inventory and we will update these estimates. We expect the results of this study will significantly improve upon existing work in quantifying CH4 and CO emissions in California's urban and rural regions.

  4. Spectroscopic Observations of the Bright Afterglow of GRB021004

    NASA Astrophysics Data System (ADS)

    Harrison, Fiona

    2001-09-01

    One of the holy grails of gamma-ray burst research is to detect X-ray line signatures from an afterglow with high statistical significance. Of all possible observations, this perhaps offers the best chance of constraining the GRB mechanism and environment, and could provide the "smoking gun" signature connecting GRBs to massive stellar deaths. In order to accomplish this, we know long observations within one day of the event are necessary.

  5. Spectroscopic observation of nitrogen anions N(-) in solid matrices.

    PubMed

    Boltnev, R E; Bykhalo, I B; Krushinskaya, I N; Pelmenev, A A; Mao, S; Meraki, A; McColgan, P T; Lee, D M; Khmelenko, V V

    2016-06-21

    Analysis of old and recent experiments on thermoluminescence of cryocrystals and nanoclusters of N2, Ne, Ar, and Kr containing stabilized nitrogen atoms, suggests that the so-called γ-line may correspond to the bound-bound transition (1)D-(3)P of nitrogen anions N(-) formed in solids by the association of delocalized electrons and metastable nitrogen atoms N((2)D). The recent observations of the γ-line were accompanied by simultaneous luminescence of metastable nitrogen N((2)D) atoms and exoelectron emission. The fine structure of the γ-line at 793 nm has been experimentally observed and investigated for the first time. PMID:27241627

  6. SOHO/UVCS spectroscopic observations of coronal oscillations

    NASA Astrophysics Data System (ADS)

    Mancuso, Salvatore; Raymond, John C.; Rubinetti, Sara; Taricco, Carla

    2016-06-01

    We analyzed the temporal evolution of the intensities and Doppler shifts of two sets of high-cadence sit-and-stare observations acquired with the Ultraviolet Coronagraph Spectrometer (UVCS) on board the Solar and Heliospheric Observatory (SOHO) satellite to detect the possible signature of wave and oscillatory motions in the solar corona. The first set of data consisted of H I Lyα observations collected on 1997 December 14 at 1.43 RS above the eastern limb of the Sun. Spectral analysis of the data revealed clear Doppler-shift oscillations with period P = 14.3 min over a portion of the UVCS slit. The origin of these oscillations is attributable to the excitation of propagating fast-mode magnetoacoustic kink waves along a narrow, jet-like ejection observed higher up in the white-light corona. The second set of data consisted of O VI 1032 Å observations collected on 1996 December 19 at 1.38 RS above the north polar coronal hole. In this case, clear intensity oscillations (P = 19.5 min) and Doppler-shift oscillations (P = 7.2 min) over two different portions of the UVCS slit were detected. The origin of these oscillations is attributable to the excitation of slow-mode magnetoacoustic waves propagating along polar plumes that may partially account for heating of the plasma in the corona.

  7. Spectroscopic Observations of the 2011 Draconids Meteor Shower

    NASA Astrophysics Data System (ADS)

    Rudawska, Regina; Zender, Joe; Jenniskens, Peter; Vaubaillon, Jeremie; Koten, Pavel; Margonis, Anastasios; Tóth, Juraj; McAuliffe, Jonathan; Koschny, Detlef

    2014-08-01

    Some past October Draconid shower meteoroids fell apart in a spray of fragments at the end of their trajectory before slowing down, from which it was concluded that these were among the most fragile meteoroids known. In those instances, the dust could not be reliably traced to a particular return of the parent comet 21P/Giaconini-Zinner. On October 8th, 2011, Earth was predicted to transverse the 1900 A.D. dust ejecta of the comet. In 1900, the comet's perihelion distance first moved significantly inwards to the Sun and ejection conditions could have been unusual. An airborne observing campaign was organized, with several teams contributing imaging and spectrographic cameras to study the manner in which these meteoroids released the volatile element sodium during the ablation process in the Earth's atmosphere. IMCCE, ESA, and the SETI Institute contributed spectrographic cameras based on low-light WATEC 902H2 Ultimate, low-light LCC1, and GenII XX1332 image intensified cameras. An outburst was observed, much as predicted. Despite a lack of bright meteors, a total of 15 Draconid spectra were recorded. All show evidence of an early release of sodium. The loss of sodium was observed to coincide with the formation of a distinct wake of fragments. The observations show that 21P/Giacobini-Zinner ejected fragile meteoroids during the return in 1900. Those grains may have lost some sodium even before impacting Earth.

  8. Spectroscopic observations of southern nearby galaxies. I. NGC 2442

    NASA Astrophysics Data System (ADS)

    Bajaja, E.; Agüero, E.; Paolantonio, S.

    1999-04-01

    The galaxy NGC 2442 was observed with a REOSC spectrograph, installed in the 2.15 m CASLEO telescope, in order to derive galactic parameters from the observed optical lines and to compare them with the results of radioastronomical observations made in the continuum, at 843 MHz, with the MOST and in the CO lines with the SEST telescope. Recent publications allowed us to extend the comparison to results from interferometric observations of Hα and H I 21 cm lines and of the continuum at 1415 MHz. The long slit observations were made placing the 5farcm 8 slit at six different positions on the optical image of the galaxy. The emission line intensity ratios at the nuclear region indicate that NGC 2442 is a LINER. The electron temperature and volume density are Te ~ 14 000 K and Ne ~ 530 cm(-3) , respectively. In contrast, a spectrum of a region 87arcsec to the NE shows the typical characteristics of a H Ii region. In this case Te ~ 6,500 K and Ne ~ 10 cm(-3) . Good correlations between the distributions of intensities, velocity fields and rotation curves have been found for the optical and radio lines. It is shown that the three intensity peaks along the line at PA = 40degr were not resolved by the observations at radio frequencies. The steep central rotation curve seen in CO has been confirmed and improved showing the existence of a disc or a ring, with a radius of 12.5 arcsec, rotating at 216/sin(i) km s(-1). Two velocity components in three optical spectra obtained in the nuclear region, have been related to two small Hα regions close to the nucleus and to the central ring. Asymmetries in the distributions of the emitting sources and irregularities in their velocity fields indicate the need of modelling the galaxy before any dynamical study is attempted. Based on observations made in the Complejo Astronomico El Leoncito, operated under agreement between the Consejo Nacional de Investigaciones Cientificas y Tecnicas de la Republica Argentina and the National

  9. Physical properties of orbital debris from spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Jorgensen, K.; Africano, J.; Hamada, K.; Stansbery, E.; Sydney, P.; Kervin, P.

    2004-01-01

    Currently, certain physical properties, such as material type and albedo, of orbital debris are assumed when used to determine the size of the objects. A study to ascertain whether or not the assumed values are valid has begun using reflectance spectroscopy as a means of determining the material type of the object. What appears to some as a squiggly line is actually the reflectance of sunlight from the object. By comparing the location, depth, and width of the absorption features on the squiggly lines, the material type of the debris object is identified. Once the material type is known, the albedo of the object can be determined. This paper discusses the results from observations of large rocket bodies and satellites in both lower and geosynchronous Earth orbits (LEO and GEO, respectively) taken at the air force maui optical and supercomputing (AMOS) site located in Maui, Hawaii. Using the 1.6-m telescope and a spectral range of 0.3-0.9 μm, differences between rocket bodies of different types and launch dates, as well as satellites of different types and launch dates are determined. Variations seen in the squiggle lines are due to colors of paint, space weathering, and for the satellites, orientation and size of the solar panels. Future direction of the project will be discussed as well as plans for future observations.

  10. Spitzer mid-infrared spectroscopic observations of planetary nebulae

    NASA Astrophysics Data System (ADS)

    Mata, H.; Ramos-Larios, G.; Guerrero, M. A.; Nigoche-Netro, A.; Toalá, J. A.; Fang, X.; Rubio, G.; Kemp, S. N.; Navarro, S. G.; Corral, L. J.

    2016-06-01

    We present Spitzer Space Telescope archival mid-infrared (mid-IR) spectroscopy of a sample of 11 planetary nebulae (PNe). The observations, acquired with the Spitzer Infrared Spectrograph (IRS), cover the spectral range 5.2-14.5 μm that includes the H2 0-0 S(2) to S(7) rotational emission lines. This wavelength coverage has allowed us to derive the Boltzmann distribution and calculate the H2 rotational excitation temperature (Tex). The derived excitation temperatures have consistent values ≃900 ± 70 K for different sources despite their different structural components. We also report the detection of mid-IR ionic lines of [Ar III], [S IV], and [Ne II] in most objects, and polycyclic aromatic hydrocarbon features in a few cases. The decline of the [Ar III]/[Ne II] line ratio with the stellar effective temperature can be explained either by a true neon enrichment or by high density circumstellar regions of PNe that presumably descend from higher mass progenitor stars.

  11. Spectroscopic observations of the detached binary PG 1413 + 015

    NASA Technical Reports Server (NTRS)

    Fulbright, Michael S.; Liebert, James; Bergeron, P.; Green, Richard

    1993-01-01

    We present improved estimates of the stellar parameters of the eclipsing, precataclysmic binary system PG 1413 + 015 (GH Vir), which has an orbital period of only 8h16m. Model atmosphere fits a Balmer line profiles yield T(eff) = 48,800 +/- 1200 K and log g = 7.70 +/- 0.11 for the DAO white dwarf primary star, from which a mass of 0.51 +/- 0.04 solar mass is inferred using evolutionary models. An ultraviolet spectrum obtained with the IUE Observatory has a slope consistent with this temperature and the assumption of no interstellar extinction. A red CCD spectrum of the secondary star during the 12-minute total eclipse indicates a spectral type of M3 V-M5 V. Reanalysis of the eclipse light curve leads to an inferred radius of 0.15 solar radius and a mass of 0.10 solar mass for the secondary, the latter being marginally consistent with the spectral type. Reprocessing on the facing side of the secondary produces phase-dependent Balmer line emission and detectable variations in the continuum from 6500-9000 A. The observed levels of reprocessing are consistent with expectations based on the above stellar parameters.

  12. VizieR Online Data Catalog: Spectroscopic observations of HD 152219 (Sana, 2009)

    NASA Astrophysics Data System (ADS)

    Sana, H.

    2009-05-01

    Journal the spectroscopic observations of HD 152219 and radial velocity measurements of the Hbeta, HeI 4712, 4921, 5875, 6678 and HeII l4686 primary lines. Measurements made on data from Paper I (Sana et al., 2008, Cat. ) have also been included. (1 data file).

  13. Photoelectric and Spectroscopic Observations Related to a Possible Optical Counterpart for Pulsar CP 1919+21.

    PubMed

    Lynds, R; Maran, S P; Trumbo, D E

    1968-07-01

    Spectroscopic observations of the two stars near the pulsar CP 1919+21 are not sufficiently conclusive to permit an identification of either object with the source of the radio pulses. However, our most extensive series of photometric observations of a region of sky near the radio source position, which region includes the brighter of the two stars, suggests an approximately sinusoidal variation. It is significant that the period of the variation is double the period of the radio pulsations.

  14. Photoelectric and Spectroscopic Observations Related to a Possible Optical Counterpart for Pulsar CP 1919+21.

    PubMed

    Lynds, R; Maran, S P; Trumbo, D E

    1968-07-01

    Spectroscopic observations of the two stars near the pulsar CP 1919+21 are not sufficiently conclusive to permit an identification of either object with the source of the radio pulses. However, our most extensive series of photometric observations of a region of sky near the radio source position, which region includes the brighter of the two stars, suggests an approximately sinusoidal variation. It is significant that the period of the variation is double the period of the radio pulsations. PMID:17756510

  15. Optical Spectroscopic Observations of Gamma-Ray Blazar Candidates. VI. Further Observations from TNG, WHT, OAN, SOAR, and Magellan Telescopes

    NASA Astrophysics Data System (ADS)

    Álvarez Crespo, N.; Massaro, F.; Milisavljevic, D.; Landoni, M.; Chavushyan, V.; Patiño-Álvarez, V.; Masetti, N.; Jiménez-Bailón, E.; Strader, J.; Chomiuk, L.; Katagiri, H.; Kagaya, M.; Cheung, C. C.; Paggi, A.; D'Abrusco, R.; Ricci, F.; La Franca, F.; Smith, Howard A.; Tosti, G.

    2016-04-01

    Blazars, one of the most extreme classes of active galaxies, constitute so far the largest known population of γ-ray sources, and their number is continuously growing in the Fermi catalogs. However, in the latest release of the Fermi catalog there is still a large fraction of sources that are classified as blazar candidates of uncertain type (BCUs) for which optical spectroscopic observations are necessary to confirm their nature and their associations. In addition, about one-third of the γ-ray point sources listed in the Third Fermi-LAT Source Catalog (3FGL) are still unassociated and lacking an assigned lower-energy counterpart. Since 2012 we have been carrying out an optical spectroscopic campaign to observe blazar candidates to confirm their nature. In this paper, the sixth of the series, we present optical spectroscopic observations for 30 γ-ray blazar candidates from different observing programs we carried out with the Telescopio Nazionale Galileo, William Herschel Telescope, Observatorio Astronómico Nacional, Southern Astrophysical Research Telescope, and Magellan Telescopes. We found that 21 out of 30 sources investigated are BL Lac objects, while the remaining targets are classified as flat-spectrum radio quasars showing the typical broad emission lines of normal quasi-stellar objects. We conclude that our selection of γ-ray blazar candidates based on their multifrequency properties continues to be a successful way to discover potential low-energy counterparts of the Fermi unidentified gamma-ray sources and to confirm the nature of BCUs.

  16. Massive Young Stellar Objects in the Galactic Center. 1; Spectroscopic Identification from Spitzer/IRS Observations

    NASA Technical Reports Server (NTRS)

    An, Deokkeun; Ramirez, Solange V.; Sellgren, Kris; Arendt, Richard G.; Boogert, A. C. Adwin; Robitaille, Thomas P.; Schultheis, Mathias; Cotera, Angela S.; Smith, Howard A.; Stolovy, Susan R.

    2011-01-01

    We present results from our spectroscopic study, using the Infrared Spectrograph (IRS) onboard the Spitzer Space Telescope, designed to identify massive young stellar objects (YSOs) in the Galactic Center (GC). Our sample of 107 YSO candidates was selected based on IRAC colors from the high spatial resolution, high sensitivity Spitzer/IRAC images in the Central Molecular Zone (CMZ), which spans the central approximately 300 pc region of the Milky Way Galaxy. We obtained IRS spectra over 5 micron to 35 micron using both high- and low-resolution IRS modules. We spectroscopically identify massive YSOs by the presence of a 15.4 micron shoulder on the absorption profile of 15 micron CO2 ice, suggestive of CO2 ice mixed with CH30H ice on grains. This 15.4 micron shoulder is clearly observed in 16 sources and possibly observed in an additional 19 sources. We show that 9 massive YSOs also reveal molecular gas-phase absorption from C02, C2H2, and/or HCN, which traces warm and dense gas in YSOs. Our results provide the first spectroscopic census of the massive YSO population in the GC. We fit YSO models to the observed spectral energy distributions and find YSO masses of 8 - 23 solar Mass, which generally agree with the masses derived from observed radio continuum emission. We find that about 50% of photometrically identified YSOs are confirmed with our spectroscopic study. This implies a preliminary star formation rate of approximately 0.07 solar mass/yr at the GC.

  17. MASSIVE YOUNG STELLAR OBJECTS IN THE GALACTIC CENTER. I. SPECTROSCOPIC IDENTIFICATION FROM SPITZER INFRARED SPECTROGRAPH OBSERVATIONS

    SciTech Connect

    An, Deokkeun; RamIrez, Solange V.; Boogert, A. C. Adwin; Sellgren, Kris; Arendt, Richard G.; Schultheis, Mathias; Cotera, Angela S.; Stolovy, Susan R.

    2011-08-01

    We present results from our spectroscopic study, using the Infrared Spectrograph (IRS) on board the Spitzer Space Telescope, designed to identify massive young stellar objects (YSOs) in the Galactic center (GC). Our sample of 107 YSO candidates was selected based on Infrared Array Camera (IRAC) colors from the high spatial resolution, high sensitivity Spitzer/IRAC images in the Central Molecular Zone, which spans the central {approx}300 pc region of the Milky Way. We obtained IRS spectra over 5-35 {mu}m using both high- and low-resolution IRS modules. We spectroscopically identify massive YSOs by the presence of a 15.4 {mu}m shoulder on the absorption profile of 15 {mu}m CO{sub 2} ice, suggestive of CO{sub 2} ice mixed with CH{sub 3}OH ice on grains. This 15.4 {mu}m shoulder is clearly observed in 16 sources and possibly observed in an additional 19 sources. We show that nine massive YSOs also reveal molecular gas-phase absorption from CO{sub 2}, C{sub 2}H{sub 2}, and/or HCN, which traces warm and dense gas in YSOs. Our results provide the first spectroscopic census of the massive YSO population in the GC. We fit YSO models to the observed spectral energy distributions and find YSO masses of 8-23 M{sub sun}, which generally agree with the masses derived from observed radio continuum emission. We find that about 50% of photometrically identified YSOs are confirmed with our spectroscopic study. This implies a preliminary star formation rate of {approx}0.07 M{sub sun} yr{sup -1} at the GC.

  18. SPECTROSCOPIC OBSERVATIONS OF AN EVOLVING FLARE RIBBON SUBSTRUCTURE SUGGESTING ORIGIN IN CURRENT SHEET WAVES

    SciTech Connect

    Brannon, S. R.; Longcope, D. W.; Qiu, J.

    2015-09-01

    We present imaging and spectroscopic observations from the Interface Region Imaging Spectrograph of the evolution of the flare ribbon in the SOL2014-04-18T13:03 M-class flare event, at high spatial resolution and time cadence. These observations reveal small-scale substructure within the ribbon, which manifests as coherent quasi-periodic oscillations in both position and Doppler velocities. We consider various alternative explanations for these oscillations, including modulation of chromospheric evaporation flows. Among these, we find the best support for some form of wave localized to the coronal current sheet, such as a tearing mode or Kelvin–Helmholtz instability.

  19. Spectroscopic observation of CSS161010 and SN2016gxp by NUTS (NOT Un-biased Transient Survey)

    NASA Astrophysics Data System (ADS)

    Reynolds, T.; Dong, S.; Fraser, M.; Stritzinger, M.; Mattila, S.; Lundqvist, P.; Elias-Rosa, N.; Harmanen, J.; Kangas, T.; Somero, A.; Kuncarayakti, H.; Taddia, F.

    2016-10-01

    The Nordic Optical Telescope (NOT) Unbiased Transient Survey (NUTS; ATel #8992) reports the spectroscopic classification of the hostless transient CSS161010:045834-081803 and further observation of SN2016gxp in NGC51.

  20. ASASSN-15th (M33N 2015-12a): Additional Spectroscopic Observations

    NASA Astrophysics Data System (ADS)

    Darnley, M. J.; Williams, S. C.

    2015-12-01

    We report additional spectroscopic observations of the developing M33 nova eruption ASASSN-15th (M33N 2015-12a; see ATel #8349, #8352). The low resolution, high throughput, SPRAT instrument on the 2m fully-robotic Liverpool Telescope obtained three 600s spectra of ASASSN-15th at 2015 Dec. 10.9 UT. These spectra show significant evolution from that reported in ATel #8352, in that the deep P Cygni profiles seen in the few days after discovery have now almost completely disappeared, with the emission component of these lines growing in strength.

  1. Observation of hydrofluoric acid burns on osseous tissues by means of terahertz spectroscopic imaging.

    PubMed

    Baughman, William E; Yokus, Hamdullah; Balci, Soner; Wilbert, David Shawn; Kung, Patrick; Kim, Seongsin Margaret

    2013-07-01

    Terahertz technologies have gained great amount of attention for biomedical imaging and tissue analysis. In this study, we utilize terahertz imaging to study the effects of hydrofluoric acid on both compact bone tissue and cartilage. We compare the differences observed in the exposure for formalin fixed and raw, dried, tissue as well as those resulting from a change in hydrofluoric (HF) concentration. Measurements are performed with THz-TDS, and a variety of spectroscopic-based image reconstruction techniques are utilized to develop contrast in the features of interest.

  2. Spectroscopic observations of the counterpart of IGR J00291+5934

    NASA Astrophysics Data System (ADS)

    Roelofs, G.; Jonker, P. G.; Steeghs, D.; Torres, M.; Nelemans, G.

    2004-12-01

    Spectroscopic observations of the optical counterpart of the millisecond X-ray pulsar IGR J00291+5934 (Atel #352, 353) reported in an Atel by Fox & Kulkarni were obtained (Dec 5 00:29-01:15 UT) with the ISIS spectrograph mounted on the 4.2m William Herschel Telescope on La Palma. Weather conditions were not optimal with a seeing of ~2" and thin clouds. The spectra show weak evidence for broad emission line features near the HeII line at 4686 Angstrom and near the Halpha line at 6563 Angstrom.

  3. Observation of Frenkel and charge transfer excitons in pentacene single crystals using spectroscopic generalized ellipsometry

    NASA Astrophysics Data System (ADS)

    Qi, Dongchen; Su, Haibin; Bastjan, M.; Jurchescu, O. D.; Palstra, T. M.; Wee, Andrew T. S.; Rübhausen, M.; Rusydi, A.

    2013-09-01

    We report on the emerging and admixture of Frenkel and charge transfer (CT) excitons near the absorption onset in pentacene single crystals. Using high energy-resolution spectroscopic generalized ellipsometry with in-plane polarization dependence, the excitonic nature of three lowest lying excitations is discussed. Their distinct polarization dependence strongly indicates the presence of both Frenkel and CT types of excitons near the excitation onset. In particular, the peculiar polarization behavior of the second excitation can only be rationalized by taking into account the inherent CT transition dipole moment. This observation has important implications for the pentacene-based optoelectronic devices.

  4. Spectroscopic observations of V443 Herculis - A symbiotic binary with a low mass white dwarf

    NASA Technical Reports Server (NTRS)

    Dobrzycka, Danuta; Kenyon, Scott J.; Mikolajewska, Joanna

    1993-01-01

    We present an analysis of new and existing photometric and spectroscopic observations of the symbiotic binary V443 Herculis. This binary system consists of a normal M5 giant and a hot compact star. These two objects have comparable luminosities: about 1500 solar for the M5 giant and about 1000 solar for the compact star. We identify three nebular regions in this binary: a small, highly ionized volume surrounding the hot component, a modestly ionized shell close to the red giant photosphere, and a less dense region of intermediate ionization encompassing both binary components. The system parameters for V443 Her suggest the hot component currently declines from a symbiotic nova eruption.

  5. Adventures in the World of Pulsating Variable Stars: Multisite Photometric Campaigns

    NASA Astrophysics Data System (ADS)

    Szabó, R.

    2004-06-01

    Advantages of photometric multisite campaigns are discussed, then published or prospective results of four - preceding and ongoing - observing runs are presented. Prospects and limits of photometric observations carried out from Hungary with small (~ 1m) telescopes are also outlined.

  6. Low X-Ray Luminosity Galaxy Clusters: Main Goals, Sample Selection, Photometric and Spectroscopic Observations

    NASA Astrophysics Data System (ADS)

    Nilo Castellón, José Luis; Alonso, M. Victoria; García Lambas, Diego; Valotto, Carlos; O'Mill, Ana Laura; Cuevas, Héctor; Carrasco, Eleazar R.; Ramírez, Amelia; Astudillo, José M.; Ramos, Felipe; Jaque Arancibia, Marcelo; Ulloa, Natalie; Órdenes, Yasna

    2016-06-01

    We present our study of 19 low X-ray luminosity galaxy clusters (L{}X ˜ 0.5-45 × 1043 erg s-1), selected from the ROSAT Position Sensitive Proportional Counters Pointed Observations and the revised version of Mullis et al. in the redshift range of 0.16-0.7. This is the introductory paper of a series presenting the sample selection, photometric and spectroscopic observations, and data reduction. Photometric data in different passbands were taken for eight galaxy clusters at Las Campanas Observatory; three clusters at Cerro Tololo Interamerican Observatory; and eight clusters at the Gemini Observatory. Spectroscopic data were collected for only four galaxy clusters using Gemini telescopes. Using the photometry, the galaxies were defined based on the star-galaxy separation taking into account photometric parameters. For each galaxy cluster, the catalogs contain the point-spread function and aperture magnitudes of galaxies within the 90% completeness limit. They are used together with structural parameters to study the galaxy morphology and to estimate photometric redshifts. With the spectroscopy, the derived galaxy velocity dispersion of our clusters ranged from 507 km s-1 for [VMF98]022 to 775 km s-1 for [VMF98]097 with signs of substructure. Cluster membership has been extensively discussed taking into account spectroscopic and photometric redshift estimates. In this sense, members are the galaxies within a projected radius of 0.75 Mpc from the X-ray emission peak and with clustercentric velocities smaller than the cluster velocity dispersion or 6000 km s-1, respectively. These results will be used in forthcoming papers to study, among the main topics, the red cluster sequence, blue cloud and green populations, the galaxy luminosity function, and cluster dynamics.

  7. Chemical Nature Of Titan’s Organic Aerosols Constrained from Spectroscopic and Mass Spectrometric Observations

    NASA Astrophysics Data System (ADS)

    Imanaka, Hiroshi; Cruikshank, D. P.

    2012-10-01

    The Cassini-Huygens observations greately extend our knowledge about Titan’s organic aerosols. The Cassini INMS and CAPS observations clearly demonstrate the formation of large organic molecules in the ionosphere [1, 2]. The VIMS and CIRS instruments have revealed spectral features of the haze covering the mid-IR and far-IR wavelengths [3, 4, 5, 6]. This study attempts to speculate the possible chemical nature of Titan’s aerosols by comparing the currently available observations with our laboratory study. We have conducted a series of cold plasma experiment to investigate the mass spectrometric and spectroscopic properties of laboratory aerosol analogs [7, 8]. Titan tholins and C2H2 plasma polymer are generated with cold plasma irradiations of N2/CH4 and C2H2, respectively. Laser desorption mass spectrum of the C2H2 plasma polymer shows a reasonable match with the CAPS positive ion mass spectrum. Furthermore, spectroscopic features of the the C2H2 plasma polymer in mid-IR and far-IR wavelegths qualitatively show reasonable match with the VIMS and CIRS observations. These results support that the C2H2 plasma polymer is a good candidate material for Titan’s aerosol particles at the altitudes sampled by the observations. We acknowledge funding supports from the NASA Cassini Data Analysis Program, NNX10AF08G, and from the NASA Exobiology Program, NNX09AM95G, and the Cassini Project. [1] Waite et al. (2007) Science 316, 870-875. [2] Crary et al. (2009) Planet. Space Sci. 57, 1847-1856. [3] Bellucci et al. (2009) Icarus 201, 198-216. [4] Anderson and Samuelson (2011) Icarus 212, 762-778. [5] Vinatier et al. (2010) Icarus 210, 852-866. [6] Vinatier et al. (2012) Icarus 219, 5-12. [7] Imanaka et al. (2004) Icarus 168, 344-366. [8] Imanaka et al. (2012) Icarus 218, 247-261.

  8. High-Resolution Spectroscopic Database for the NASA Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Rothman, Laurence S.; Starr, David (Technical Monitor)

    2002-01-01

    The purpose of this project is to develop and enhance the HITRAN molecular spectroscopic database and associated software to support the observational programs of the Earth Observing System (EOS). In particular, the focus is on the EOS projects: the Atmospheric Infrared Sounder (AIRS), the High-Resolution Dynamics Limb Sounder (HIRDLS), Measurements of Pollution in the Troposphere (MOPITT), the Tropospheric Emission Spectrometer (TES), and the Stratospheric Aerosol and Gas Experiment (SAGE III). The data requirements of these programs in terms of spectroscopy are varied, but usually call for additional spectral parameters or improvements to existing molecular bands. In addition, cross-section data for heavier molecular species must be expanded and made amenable to modeling in remote sensing. The effort in the project also includes developing software and distribution to make access, manipulation, and use of HITRAN functional to the EOS program.

  9. Direct spectroscopic observation of a shallow hydrogenlike donor state in insulating SrTiO3.

    PubMed

    Salman, Z; Prokscha, T; Amato, A; Morenzoni, E; Scheuermann, R; Sedlak, K; Suter, A

    2014-10-10

    We present a direct spectroscopic observation of a shallow hydrogenlike muonium state in SrTiO(3) which confirms the theoretical prediction that interstitial hydrogen may act as a shallow donor in this material. The formation of this muonium state is temperature dependent and appears below ∼ 70K. From the temperature dependence we estimate an activation energy of ∼ 50 meV in the bulk and ∼ 23 meV near the free surface. The field and directional dependence of the muonium precession frequencies further supports the shallow impurity state with a rare example of a fully anisotropic hyperfine tensor. From these measurements we determine the strength of the hyperfine interaction and propose that the muon occupies an interstitial site near the face of the oxygen octahedron in SrTiO(3). The observed shallow donor state provides new insight for tailoring the electronic and optical properties of SrTiO(3)-based oxide interface systems.

  10. Comparing Simulated and Observed Spectroscopic Signatures of Mix in Omega Capsules

    NASA Astrophysics Data System (ADS)

    Tregillis, I. L.; Shah, R. C.; Hakel, P.; Cobble, J. A.; Murphy, T. J.; Krasheninnikova, N. S.; Hsu, S. C.; Bradley, P. A.; Schmitt, M. J.; Batha, S. H.; Mancini, R. C.

    2012-10-01

    The Defect-Induced Mix Experiment (DIME) campaign at Los Alamos National Laboratory uses multi-monochromatic X-ray imaging (MMI)footnotetextT. Nagayama, R.C. Mancini, R. Florido, et al, J. App. Phys. 109, 093303 (2011) to detect the migration of high-Z spectroscopic dopants into the hot core of an imploded capsule. We have developed an MMI post-processing tool for producing synthetic datasets from two- and three-dimensional Lagrangian numerical simulations of Omega and NIF shots. These synthetic datasets are of sufficient quality, and contain sufficient physics, that they can be analyzed in the same manner as actual MMI data. We have carried out an extensive comparison between simulated and observed MMI data for a series of polar direct-drive shots carried out at the Omega laser facility in January, 2011. The capsule diameter was 870 microns; the 15 micron CH ablators contained a 2 micron Ti-doped layer along the inner edge. All capsules were driven with 17 kJ; some capsules were manufactured with an equatorial ``trench'' defect. This talk will focus on the construction of spectroscopic-quality synthetic MMI datasets from numerical simulations, and their correlation with MMI measurements.

  11. Optical spectroscopic observations of γ-ray blazar candidates. I. Preliminary results

    SciTech Connect

    Paggi, A.; Milisavljevic, D.; D'Abrusco, R.; Smith, H. A.; Margutti, R.; Martínez-Galarza, J. R.; Landoni, M.; Grindlay, J. E.; Masetti, N.; Giroletti, M.; Jiménez-Bailón, E.; Otí-Floranes, H.; Chavushyan, V.; Massaro, F.; Funk, S.; Tosti, G.

    2014-05-01

    A significant fraction (∼30%) of the γ-ray sources listed in the second Fermi/LAT (2FGL) catalog is still of unknown origin, being not yet associated with counterparts at lower energies. Using the available information at lower energies and optical spectroscopy on the selected counterparts of these γ-ray objects, we can pinpoint their exact nature. Here, we present a pilot project pointing to assess the effectiveness of the several classification methods developed to select γ-ray blazar candidates. To this end, we report optical spectroscopic observations of a sample of five γ-ray blazar candidates selected on the basis of their infrared Wide-field Infrared Survey Explorer (WISE) colors or of their low-frequency radio properties. Blazars come in two main classes, BL Lac objects and FSRQs, showing similar optical spectra except for the stronger emission lines of the latter. For three of our sources, the almost featureless optical spectra obtained confirm their BL Lac nature, while for the source WISEJ022051.24+250927.6 we observe emission lines with equivalent width EW ∼ 31 Å, identifying it as a FSRQ with z = 0.48. The source WISEJ064459.38+603131.7, although not featuring a clear radio counterpart, shows a blazar-like spectrum with weak emission lines with EW ∼ 7 Å, yielding a redshift estimate of z = 0.36. In addition, we report optical spectroscopic observations of four WISE sources associated with known γ-ray blazars without a firm classification or redshift estimate. For the latter sources, we confirm a BL Lac classification, with a tentative redshift estimate for the source WISEJ100800.81+062121.2 of z = 0.65.

  12. Submillimetric spectroscopic observations of volatiles in comet C/2004 Q2 (Machholz)

    NASA Astrophysics Data System (ADS)

    de Val-Borro, M.; Hartogh, P.; Jarchow, C.; Rengel, M.; Villanueva, G. L.; Küppers, M.; Biver, N.; Bockelée-Morvan, D.; Crovisier, J.

    2012-09-01

    Context. Submillimeter spectroscopic observations of comets provide an important tool for understanding their chemical composition and enable a taxonomic classification. Aims: We aim to determine the production rates of several parent- and product volatiles and the 12C/13C isotopic carbon ratio in the long-period comet C/2004 Q2 (Machholz), which is likely to originate from the Oort Cloud. Methods: The line emission from several molecules in the coma was measured with high signal-to-noise ratio in January 2005 at heliocentric distance of 1.2 AU by means of high-resolution spectroscopic observations using the Submillimeter Telescope (SMT) at the Arizona Radio Observatory (ARO). Results: We have obtained production rates of several volatiles (CH3OH, HCN, H13CN, HNC, H2CO, CO, and CS) by comparing the observed and simulated line-integrated intensities. We calculated the synthetic profiles using a radiative transfer code that includes collisions between neutrals and electrons, and the effects of radiative pumping of the fundamental vibrational levels by solar infrared radiation. Furthermore, multiline observations of the CH3OH J = 7-6 series allow us to estimate the rotational temperature using the rotation diagram technique. We find that the CH3OH population distribution of the levels sampled by these lines can be described by a rotational temperature of 40 ± 3 K. Derived mixing ratios relative to hydrogen cyanide are CO/CH3OH/H2CO/CS/HNC/H13CN/HCN = 30.9/24.6/4.8/0.57/0.031/0.013/1 assuming a pointing offset of 8'' due to the uncertain ephemeris at the time of the observations and the telescope pointing error. Conclusions: The measured relative molecular abundances in C/2004 Q2 (Machholz) are between low- to typical values of those obtained in Oort Cloud comets, suggesting that it has visited the inner solar system previously and undergone thermal processing. The HNC/HCN abundance ratio of ~3.1% is comparable to that found in other comets, accounting for the

  13. Quantum simulation. Spectroscopic observation of SU(N)-symmetric interactions in Sr orbital magnetism.

    PubMed

    Zhang, X; Bishof, M; Bromley, S L; Kraus, C V; Safronova, M S; Zoller, P; Rey, A M; Ye, J

    2014-09-19

    SU(N) symmetry can emerge in a quantum system with N single-particle spin states when spin is decoupled from interparticle interactions. Taking advantage of the high measurement precision offered by an ultrastable laser, we report a spectroscopic observation of SU(N ≤ 10) symmetry in (87)Sr. By encoding the electronic orbital degree of freedom in two clock states while keeping the system open to as many as 10 nuclear spin sublevels, we probed the non-equilibrium two-orbital SU(N) magnetism via Ramsey spectroscopy of atoms confined in an array of two-dimensional optical traps; we studied the spin-orbital quantum dynamics and determined the relevant interaction parameters. This study lays the groundwork for using alkaline-earth atoms as testbeds for important orbital models. PMID:25147278

  14. Implementation of Multiple Spectroscopic Techniques to Simultaneously Observe Native and Mutated Protein Unfolding

    NASA Astrophysics Data System (ADS)

    Cull, Brennan; Ben, Kelty; Link, Justin

    A protein's natural, correctly folded structure can determine the protein's ability to carry out its function. If the unfolding process of proteins can be observed, then the relative stability can be better understood between native and mutated proteins. A global picture of the unfolding process may be completed through the studies of strategically mutated proteins using tryptophan as a probe. Horse heart cytochrome c, a thoroughly studied, model protein was used in our investigation to explore this idea. Various spectroscopic techniques such as circular dichroism (CD), absorbance, and fluorescence were simultaneously applied while slowly unfolding our protein by increasing the concentration of a chemical denaturant, guanidine hydrochloride. This provided us information about the thermodynamic properties of the protein and several mutants which can then be interpreted to gain relative stability information among mutations. Efforts to utilize these techniques on native and mutated proteins in comparison to current scientific unfolding theories will be presented in this session.

  15. Submillimetric Spectroscopic Observations of Volatiles in Comet C-2004 Q2 (Machholz)

    NASA Technical Reports Server (NTRS)

    DeVal-Borro, M.; Hartogh, P.; Jarchow, C.; Rengel, M.; Villanueva, G. L.; Kueppers, M.; Biver, N.; Bockelee-Morvan, D.; Crovisier, J.

    2012-01-01

    Submillimeter spectroscopic observations of comets provide an important tool for understanding their chemical composition and enable a taxonomic classification. Aims. We aim to determine the production rates of several parent- and product volatiles and the C-12/C-13 isotopic carbon ratio in the long-period comet C/2004 Q2 (Machholz), which is likely to originate from the Oort Cloud. Methods. The line emission from several molecules in the coma was measured with high signal-to-noise ratio in January 2005 at heliocentric distance of 1.2 AU by means of high-resolution spectroscopic observations using the Submillimeter Telescope (SMT) at the Arizona Radio Observatory (ARO). Results. We have obtained production rates of several volatiles (CH3OH, HCN, H(sup 13)CN, HNC, H2CO, CO, and CS) by comparing the observed and simulated line-integrated intensities. We calculated the synthetic profiles using a radiative transfer code that includes collisions between neutrals and electrons, and the effects of radiative pumping of the fundamental vibrational levels by solar infrared radiation. Furthermore, multiline observations of the CH3OH J = 7-6 series allow us to estimate the rotational temperature using the rotation diagram technique. We find that the CH3OH population distribution of the levels sampled by these lines can be described by a rotational temperature of 40 +/- 3 K. Derived mixing ratios relative to hydrogen cyanide are CO/CH3OH/H2CO/CS/HNC/HC-13N/HCN= 30.9/24.6/4.8/0.57/0.031/0.013/1 assuming a pointing offset of 8" due to the uncertain ephemeris at the time of the observations and the telescope pointing error. Conclusions. The measured relative molecular abundances in C/2004 Q2 (Machholz) are between low- to typical values of those obtained in Oort Cloud comets, suggesting that it has visited the inner solar system previously and undergone thermal processing. The HNC/HCN abundance ratio of approx 3.1% is comparable to that found in other comets, accounting for the

  16. Revised spectroscopic parameters of SH(+) from ALMA and IRAM 30m observations.

    PubMed

    Müller, Holger S P; Goicoechea, Javier R; Cernicharo, José; Agúndez, Marcelino; Pety, Jérôme; Cuadrado, Sara; Gerin, Maryvonne; Dumas, Gaëlle; Chapillon, Edwige

    2014-09-19

    Hydrides represent the first steps of interstellar chemistry. Sulfanylium (SH(+)), in particular, is a key tracer of energetic processes. We used ALMA and the IRAM 30 m telescope to search for the lowest frequency rotational lines of SH(+) toward the Orion Bar, the prototypical photo-dissociation region illuminated by a strong UV radiation field. On the basis of previous Herschel/HIFI observations of SH(+), we expected to detect emission of the two SH(+) hyperfine structure (HFS) components of the NJ = 10-01 fine structure (FS) component near 346 GHz. While we did not observe any lines at the frequencies predicted from laboratory data, we detected two emission lines, each ~15 MHz above the SH(+) predictions and with relative intensities and HFS splitting expected for SH(+). The rest frequencies of the two newly detected lines are more compatible with the remainder of the SH(+) laboratory data than the single line measured in the laboratory near 346 GHz and previously attributed to SH(+). Therefore, we assign these new features to the two SH(+) HFS components of the NJ = 10-01 FS component and re-determine its spectroscopic parameters, which will be useful for future observations of SH(+), in particular if its lowest frequency FS components are studied. Our observations demonstrate the suitability of these lines for SH(+) searches at frequencies easily accessible from the ground.

  17. IMAGING AND SPECTROSCOPIC OBSERVATIONS OF MAGNETIC RECONNECTION AND CHROMOSPHERIC EVAPORATION IN A SOLAR FLARE

    SciTech Connect

    Tian, Hui; Reeves, Katharine K.; Raymond, John C.; Chen, Bin; Murphy, Nicholas A.; Li, Gang; Guo, Fan; Liu, Wei

    2014-12-20

    Magnetic reconnection is believed to be the dominant energy release mechanism in solar flares. The standard flare model predicts both downward and upward outflow plasmas with speeds close to the coronal Alfvén speed. Yet, spectroscopic observations of such outflows, especially the downflows, are extremely rare. With observations of the newly launched Interface Region Imaging Spectrograph (IRIS), we report the detection of a greatly redshifted (∼125 km s{sup –1} along the line of sight) Fe XXI 1354.08 Å emission line with a ∼100 km s{sup –1} nonthermal width at the reconnection site of a flare. The redshifted Fe XXI feature coincides spatially with the loop-top X-ray source observed by RHESSI. We interpret this large redshift as the signature of downward-moving reconnection outflow/hot retracting loops. Imaging observations from both IRIS and the Atmospheric Imaging Assembly (AIA) on board the Solar Dynamics Observatory also reveal the eruption and reconnection processes. Fast downward-propagating blobs along these loops are also found from cool emission lines (e.g., Si IV, O IV, C II, Mg II) and images of AIA and IRIS. Furthermore, the entire Fe XXI line is blueshifted by ∼260 km s{sup –1} at the loop footpoints, where the cool lines mentioned above all exhibit obvious redshift, a result that is consistent with the scenario of chromospheric evaporation induced by downward-propagating nonthermal electrons from the reconnection site.

  18. High Resolution Spectroscopic Database for the NASA Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Rothman, Laurence

    2004-01-01

    The purpose of this project has been to develop and enhance the HITRAN molecular spectroscopic database and associated software to support the observational programs of the Earth Observing System (EOS). Emphasis has been on the EOS projects: the Atmospheric Infrared Sounder (AIRS), the High-Resolution Dynamics Limb Sounder (HIRDLS), Measurements of Pollution in the Troposphere (MOPITT), the Tropospheric Emission Spectrometer (TES), and the Stratospheric Aerosol and Gas Experiment (SAGE III). The HITRAN program is also involved in the Ozone Monitoring Experiment (OMI). The data requirements of these programs in terms of spectroscopy are varied with respect to constituents being observed, required remote-sensing parameters, and spectral coverage. A general requisite is for additional spectral parameters and improvements to existing molecular bands sufficient for the simulation of the observations leading to retrieval of the atmospheric state. In addition, cross-section data for heavier molecular species must be expanded and made amenable to modeling in remote sensing. The effort in the project also includes developing software and distribution to make access, manipulation, and use of HITRAN functional to the EOS program.

  19. High-Resolution Spectroscopic Database for the NASA Earth Observing System Program

    NASA Technical Reports Server (NTRS)

    Rothman, Laurence S.

    2004-01-01

    The purpose of this project is to develop and enhance the HITRAN molecular spectroscopic database and associated - software to support the observational programs of the Earth observing System (EOS). In particular, the focus is on the EOS projects: the Atmospheric Infrared Sounder (AIRS), the High-Resolution Dynamics Limb Sounder (HIRDLS), Measurements of Pollution in the Troposphere (MOPITT), the Tropospheric Emission Spectrometer (TES), and the Stratospheric Aerosol and Gas Experiment (SAGE III). The HITRAN program is also involved in the Ozone Monitoring Experiment (OMI). The data requirements of these programs in terms of spectroscopy are varied with respect to constituents being observed, required remote-sensing parameters, and spectral coverage. A general requisite is for additional spectral parameters and improvements to existing molecular bands sufficient for the simulation of the observations leading to retrieval of the atmospheric state. In addition cross-section data for heavier molecular species must be expanded and made amenable to modeling in remote sensing. The effort in the project also includes developing software and distribution to make access, manipulation, and use HITRAN functional to the EOS program.

  20. Revised spectroscopic parameters of SH(+) from ALMA and IRAM 30m observations.

    PubMed

    Müller, Holger S P; Goicoechea, Javier R; Cernicharo, José; Agúndez, Marcelino; Pety, Jérôme; Cuadrado, Sara; Gerin, Maryvonne; Dumas, Gaëlle; Chapillon, Edwige

    2014-09-19

    Hydrides represent the first steps of interstellar chemistry. Sulfanylium (SH(+)), in particular, is a key tracer of energetic processes. We used ALMA and the IRAM 30 m telescope to search for the lowest frequency rotational lines of SH(+) toward the Orion Bar, the prototypical photo-dissociation region illuminated by a strong UV radiation field. On the basis of previous Herschel/HIFI observations of SH(+), we expected to detect emission of the two SH(+) hyperfine structure (HFS) components of the NJ = 10-01 fine structure (FS) component near 346 GHz. While we did not observe any lines at the frequencies predicted from laboratory data, we detected two emission lines, each ~15 MHz above the SH(+) predictions and with relative intensities and HFS splitting expected for SH(+). The rest frequencies of the two newly detected lines are more compatible with the remainder of the SH(+) laboratory data than the single line measured in the laboratory near 346 GHz and previously attributed to SH(+). Therefore, we assign these new features to the two SH(+) HFS components of the NJ = 10-01 FS component and re-determine its spectroscopic parameters, which will be useful for future observations of SH(+), in particular if its lowest frequency FS components are studied. Our observations demonstrate the suitability of these lines for SH(+) searches at frequencies easily accessible from the ground. PMID:26525172

  1. Ground-Based Thermal-IR Spectroscopic Observations of Jupiter During the Galileo Encounter

    NASA Astrophysics Data System (ADS)

    Sada, P. V.; Jennings, D.; McCabe, G.; Deming, D.; Bjoraker, G.

    1995-12-01

    High resolution spectroscopic observations of Jupiter at selected thermal-infrared wavelengths are scheduled to be performed using CELESTE, a Goddard-developed cryogenic echelle spectrometer. These observations will be carried out in conjunction with the McMath-Pierce 60-inch Solar Telescope (KPNO/NSO) during the inital encounter phase of the Galileo spacecraft with the planet. This arrangement was successfully used in 1994-95 to perform daytime observations of Jupiter close to the Sun. The planet will be located 9(deg) away from the Sun in the sky on 7 December 1995, the day Galileo's probe is scheduled to enter the atmosphere of the planet. Galileo's entry probe is programmed to shed its heat shield and start directly sampling the atmosphere of Jupiter at a pressure level of about 100 mbar. We plan to carry out observations of a complementary nature to those of the entry probe by using molecular species which better sample the stratosphere of Jupiter. These observations, in conjunction with those obtained by Galileo, will help characterize the state of the atmosphere of Jupiter at the time of the encounter. In particular we plan to observe the 587 cm(-1) S(1) quadrupole line of H2, which yields abundance-independent temperature information on the upper troposphere and lower stratosphere of Jupiter. We also plan to measure strong stratospheric emission features from molecules such as CH4, C2H6, and C2H2. These spectral observations will be used to retrieve temperature and species abundance information with some degree of spatial discrimination. Preliminary results from these observations will be presented. (1) National Research Council Resident Research Associate. (2) Hughes/STX.

  2. Visible Spectroscopic Observation Of Asteroid 162173 (1999ju3) With The Gemini-s Telescope

    NASA Astrophysics Data System (ADS)

    Sugita, Seiji; Kuroda, D.; Kameda, S.; Hasegawa, S.; Kamata, S.; Abe, M.; Ishiguro, M.; Takato, N.; Yoshikawa, M.

    2012-10-01

    Asteroid 162173 (1999JU3; hereafter JU3) is the target of the Hayabusa-2 mission. Its visible reflectance spectra have been observed a few times [1,2], and obtained spectra exhibit a wide variety of spectral patterns ranging from a spectra with absorption in the UV region (May 1999) to a flat spectrum with a faint broad absorption centered around 0.6 microns (September 2007) and that with UV absorption and strong broad absorption centered around 0.7 micron (July 2007). The apparent large spectral variation may be due to variegation on the asteroid surface. Such variegation would make a large influence on remote sensing strategy for Hayabusa-2 before its sampling operations. In order to better constraint the spectral properties of JU3, we conducted visible spectroscopic observations at the GEMINI-South observatory 8.1-m telescope with the GMOS instrument. We could obtain three different sets of data in June and July 2012. Although the JU3 rotation phases of two of the observation are close to each other, the other is about 120 degrees away from the two. Our preliminary analyses indicate that these three spectra are slightly reddish but generally flat across the observed wavelength range (0.47 - 0.89 microns). The observed flat spectra are most similar to the spectrum obtained in September 2007, which probably has the highest signal-to-noise ratio among the previous three spectra. This result suggests that material with a flat spectrum probably covers a dominant proportion of the JU3 surface and that the other two types of previously obtained spectra may not cover a very large fraction of the JU3 surface. [1] Binzel, R. P. et al. (2001) Icarus, 151, 139-149; [2] Vilas, F. (2008) AJ, 135, 1101-1105.

  3. A SURVEY OF FAR ULTRAVIOLET SPECTROSCOPIC EXPLORER OBSERVATIONS OF CATACLYSMIC VARIABLES

    SciTech Connect

    Froning, Cynthia S.; Long, Knox S.; Gaensicke, Boris; Szkody, Paula E-mail: long@stsci.edu E-mail: szkody@alicar.astro.washington.edu

    2012-03-01

    During its lifetime, the Far Ultraviolet Spectroscopic Explorer (FUSE) was used to observe 99 cataclysmic variables (CVs) in 211 separate observations. Here, we present a survey of the moderate-resolution (R {approx_equal} 10, 000), far-ultraviolet (905-1188 A), time-averaged FUSE spectra of CVs. The FUSE spectra are morphologically diverse. They show contributions from the accretion disk, the disk chromosphere, disk outflows, and the white dwarf (WD), but the relative contribution of each component varies widely as a function of CV subtype, orbital period and evolutionary state, inclination, mass accretion rate, and magnetic field strength of the WD. The data reveal information about the structure, temperature, density and mass flow rates of the disk and disk winds, the temperature of the WD and the effects of ongoing accretion on its structure, and the long-term response of the systems to disk outbursts. The complete atlas of time-averaged FUSE spectra of CVs is available at the Multimission Archive at Space Telescope Science Institute as a High Level Science Product.

  4. Spectroscopic observations of Hot-Jupiters with the Hubble WFC3 camera

    NASA Astrophysics Data System (ADS)

    Damiano, Mario; Morello, Giuseppe; Tsiaras, Angelos; Zingales, Tiziano; Tinetti, Giovanna; ExoLights, ExoMol

    2016-10-01

    Thousands of exoplanets have been discovered with a huge range of masses, sizes and orbits. The next step to characterize them is to study their atmosphere. The atmospheres of giant planets are mostly made of hydrogen and helium. The relevant questions therefore concern the amounts of all elements other than hydrogen and helium, i.e. the heavy elements, that are present.The atmospheres of hot Jupiters present a critical advantage compared to the planets of the Solar System: their high temperature.Unlike Jupiter and Saturn, there is no cold trap in their atmosphere for species such as H2O, CH4, NH3, CO2 etc., which condense at much colder temperatures. Observations of hot gaseous exoplanets can therefore provide a unique access to their elementary composition (especially C, O, N, S) and enable the understanding of the early stage of planetary and atmospheric formation during the nebular phase and the following few millions years.Here we present new spectroscopic observations of hot-Jupiters' atmospheres obtained with the WFC3 camera. In our presentation we will focus on the data reduction method used and on the interpretation of the results through state of the art spectral retrieval models.

  5. Direct spectroscopic observation of a shallow hydrogenlike donor state in insulating SrTiO3.

    PubMed

    Salman, Z; Prokscha, T; Amato, A; Morenzoni, E; Scheuermann, R; Sedlak, K; Suter, A

    2014-10-10

    We present a direct spectroscopic observation of a shallow hydrogenlike muonium state in SrTiO(3) which confirms the theoretical prediction that interstitial hydrogen may act as a shallow donor in this material. The formation of this muonium state is temperature dependent and appears below ∼ 70K. From the temperature dependence we estimate an activation energy of ∼ 50 meV in the bulk and ∼ 23 meV near the free surface. The field and directional dependence of the muonium precession frequencies further supports the shallow impurity state with a rare example of a fully anisotropic hyperfine tensor. From these measurements we determine the strength of the hyperfine interaction and propose that the muon occupies an interstitial site near the face of the oxygen octahedron in SrTiO(3). The observed shallow donor state provides new insight for tailoring the electronic and optical properties of SrTiO(3)-based oxide interface systems. PMID:25375730

  6. Optical Spectroscopic Observations of Fragments B and C of Comet 73P/Schwassmann-Wachmann 3

    NASA Astrophysics Data System (ADS)

    Kanda, Yuichi; Mori, A.; Kobayashi, H.; Kawakita, H.

    2008-09-01

    We carried out optical low-dispersion spectroscopic observations of the brightest fragments "B” and "C” of comet 73P/Schwasmann-Wachmann 3 (hereafter SW3) by the 2-m "NAYUTA” telescope with the optical spectrograph MALLS at NHAO (Nishi-Harima Astronomical Observatory) in Japan. Comet SW3 is known as a split comet, and its fragments are the best targets to investigate homogeneity of the cometary nucleus. We observed fragments "B” and "C” in 2006 early and middle of May, in the vicinity of the closest approach to the Earth on 2006 May 12, UT. Comet SW3 approached less than 0.07AU from the Earth provided us high spatial resolution data of its coma. We report the gas production rate ratios of CN, C2, and NH2 relative to H2O and the gas-to-dust ratios of fragments "B” and "C". Both fragments are significantly depleted in C2 compared with other comets, and these fragments are similar to each other in chemical composition. This result suggests that the nucleus of the parent body of comet SW3 was homogeneous in chemistry.

  7. Far Ultraviolet Spectroscopic Explorer Observations of the Active Cool Star AB Doradus

    NASA Astrophysics Data System (ADS)

    Ake, T. B.; Dupree, A. K.; Young, P. R.; Linsky, J. L.; Malina, R. F.; Griffiths, N. W.; Siegmund, O. H. W.; Woodgate, B. E.

    2000-07-01

    Far-ultraviolet spectra were obtained of the active cool star AB Doradus (HD 36705) during the calibration and checkout period of the Far Ultraviolet Spectroscopic Explorer (FUSE) satellite. Observations in this early phase of the mission were taken at a resolving power of 12,000-15,000 (~20-25 km s-1) and covered the spectral range 905-1187 Å. The integrated spectrum exhibits strong, rotationally broadened stellar emission from C III (λλ977, 1175) and O VI (λλ1032, 1037) and many weaker lines. Strong emission lines of C III and O VI exhibit broad wings. The C III λ977 profile shows blueshifted absorption at ~30 km s-1, and C II λ1036 absorption appears superposed on emission in the wing of O VI λ1037. Rotational modulation of C III and O VI is present, in harmony with its photometric variability. Flares were detected in the brightest lines, and subexposures were analyzed to examine flux and profile variations. Downflows that extend to 600 km s-1 during a flare are found in the O VI profiles. These early observations demonstrate that FUSE will be an exceptional instrument for studying chromospheres in cool stars.

  8. Additional spectroscopic observations and Swift monitoring of the M31 nova iPTF16bqy (ASASSN-16hf)

    NASA Astrophysics Data System (ADS)

    Chinetti, K.; Darnley, M. J.; Page, K. L.; Williams, S. C.

    2016-08-01

    We report additional spectroscopic observations of the M31 nova, iPTF16bqy (ASASSN-16hf, ATels #9245, #9248). iPTF16bqy was initially classified as a Fe II nova based on spectra obtained 2016 July 14 and 15 (ATel #9248), about two days after discovery.

  9. NIR SPECTROSCOPIC OBSERVATION OF MASSIVE GALAXIES IN THE PROTOCLUSTER AT z = 3.09

    SciTech Connect

    Kubo, Mariko; Yamada, Toru; Ichikawa, Takashi; Kajisawa, Masaru; Matsuda, Yuichi; Tanaka, Ichi

    2015-01-20

    We present the results of near-infrared spectroscopic observations of the K-band-selected candidate galaxies in the protocluster at z = 3.09 in the SSA22 field. We observed 67 candidates with K {sub AB} < 24 and confirmed redshifts of the 39 galaxies at 2.0 < z {sub spec} < 3.4. Of the 67 candidates, 24 are certainly protocluster members with 3.04 ≤ z {sub spec} ≤ 3.12, which are massive red galaxies that have been unidentified in previous optical observations of the SSA22 protocluster. Many distant red galaxies (J – K {sub AB} > 1.4), hyper extremely red objects (J – K {sub AB} > 2.1), Spitzer MIPS 24 μm sources, active galactic nuclei (AGNs) as well as the counterparts of Lyα blobs and the AzTEC/ASTE 1.1 mm sources in the SSA22 field are also found to be protocluster members. The mass of the SSA22 protocluster is estimated to be ∼2-5 × 10{sup 14} M {sub ☉}, and this system is plausibly a progenitor of the most massive clusters of galaxies in the current universe. The reddest (J – K {sub AB} ≥ 2.4) protocluster galaxies are massive galaxies with M {sub star} ∼ 10{sup 11} M {sub ☉} showing quiescent star formation activities and plausibly dominated by old stellar populations. Most of these massive quiescent galaxies host moderately luminous AGNs detected by X-ray. There are no significant differences in the [O III] λ5007/Hβ emission line ratios and [O III] λ5007 line widths and spatial extents of the protocluster galaxies from those of massive galaxies at z ∼ 2-3 in the general field.

  10. Spectroscopic Observations and Analysis of the Unusual Type Ia SN1999ac

    SciTech Connect

    Garavini, G.; Aldering, G.; Amadon, A.; Amanullah, R.; Astier,P.; Balland, C.; Blanc, G.; Conley, A.; Dahlen, T.; Deustua, S.E.; Ellis,R.; Fabbro, S.; Fadeyev, V.; Fan, X.; Folatelli, G.; Frye, B.; Gates,E.L.; Gibbons, R.; Goldhaber, G.; Goldman, B.; Goobar, A.; Groom, D.E.; Haissinski, J.; Hardin, D.; Hook, I.; Howell, D.A.; Kent, S.; Kim, A.G.; Knop, R.A.; Kowalski, M.; Kuznetsova, N.; Lee, B.C.; Lidman, C.; Mendez,J.; Miller, G.J.; Moniez, M.; Mouchet, M.; Mourao, A.; Newberg, H.; Nobili, S.; Nugent, P.E.; Pain, R.; Perdereau, O.; Perlmutter, S.; Quimby, R.; Regnault, N.; Rich, J.; Richards, G.T.; Ruiz-Lapuente, P.; Schaefer, B.E.; Schahmaneche, K.; Smith, E.; Spadafora, A.L.; Stanishev,V.; Thomas, R.C.; Walton, N.A.; Wang, L.; Wood-Vasey, W.M.

    2005-07-12

    The authors present optical spectra of the peculiar Type Ia supernova (SN Ia) 1999ac. The data extend from -15 to +42 days with respect to B-band maximum and reveal an event that is unusual in several respects. prior to B-band maximum, the spectra resemble those of SN 1999aa, a slowly declining event, but possess stronger Si II and Ca II signatures (more characteristic of a spectroscopically normal SN). Spectra after B-band maximum appear more normal. The expansion velocities inferred from the Iron lines appear to be lower than average; whereas, the expansion velocity inferred from Calcium H and K are higher than average. The expansion velocities inferred from the Iron lines appear to be lower than average; whereas, the expansion velocity inferred from Calcium H and K are higher than average. The expansion velocities inferred from Si II are among the slowest ever observed, though SN 1999ac is not particularly dim. The analysis of the parameters v{sub 10}(Si II), R(Si II), v, and {Delta}m{sub 15} further underlines the unique characteristics of SN 1999ac. They find convincing evidence of C II {lambda}6580 in the day -15 spectrum with ejection velocity v > 16,000 km s{sup -1}, but this signature disappears by day -9. This rapid evolution at early times highlights the importance of extremely early-time spectroscopy.

  11. Vertical profiling of methane and carbon dioxide using high resolution near-infrared heterodyne spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Rodin, Alexander; Klimchuk, Artem; Churbanov, Dmitry; Pereslavtseva, Anastasia; Spiridonov, Maxim; Nadezhdinskyi, Alexander

    2014-05-01

    We present new method of monitoring greenhouse gases using spectroscopic observations of solar radiation passed through the atmosphere with spectral resolution ΛvδΛ up to 108. Such a high resolution is achieved by heterodyne technique and allows to retrieve full information about spectral line shape which, in turn, is used to distinguish contribution of different atmospheric layers to the resulting absorption. Weak absorption line at 6056.5 cm-1 was selected for CO2 measurements and a quartet of lines centered at 6057 cm-1for CH4. The instrument setup includes Sun tracker with a microtelescope and chopper, diode DFB laser used as a local oscillator, a bundle of single mode optical fibers that provides medium for radiation transfer and beam coupling, reference cell with depressurized methane for LO frequency stabilization, and Fabry-Perot etalon for LO frequency calibration. A commercial p-i-n diode with squared detector replaces a mixer and IF spectrometer, providing measurement of heterodyne beating within a bandpass of few MHz, which determines the effective spectral resolution of the instrument. Spectral coverage within narrow range (about 1 cm-1) is provided by ramping the LO frequency based on feedback from the reference channel. Observations of Sun in the Moscow region have resulted for the first time in measurements of the atmospheric transmission near 1.65 μm with sub-Doppler spectral resolution. In order to retrieve vertical profiles of methane and carbon dioxide we developed the inversion algorithm implementing Tikhonov regularization approach. With measured transmission having S/N ratio of 100 or higher, the uncertainty of CH4 profile is about 10 ppb, with the uncertainty of CO2 profile at 1 ppm. This techniques is promising an affordable opportunity or widespread monitoring of greenhouse gases and may be implemented on existing ground-based stations. This work has been supported by the grant of Russian Ministry of education and science #11.G34.31.0074

  12. First spectroscopic observations of the substellar companion of the young debris disk star PZ Telescopii

    NASA Astrophysics Data System (ADS)

    Schmidt, T. O. B.; Mugrauer, M.; Neuhäuser, R.; Vogt, N.; Witte, S.; Hauschildt, P. H.; Helling, Ch.; Seifahrt, A.

    2014-06-01

    Context. In 2010 a substellar companion to the solar analog pre-main sequence star PZ Tel and member of the approximately 12 Myr old β Pic moving group was found by high-contrast direct imaging independently by two teams. Aims: In order to determine the basic parameters of this companion more precisely and independent of evolutionary models, hence age-independent, we obtained follow-up spectroscopic observations of the primary and companion. Methods: We used the Spectrograph for INtegral Field Observations in the Near Infrared (SINFONI) at the Very Large Telescope Unit 4/Yepun of ESO's Paranal Observatory in the H + K band and processed the data using the spectral deconvolution technique. The resulting spectrum of the companion was then compared to a grid of Drift-Phoenix synthetic model spectra, a combination of a general-purpose model atmosphere code with a non-equilibrium, stationary cloud and dust model, using a χ2 minimization analysis. Results: We find a best fitting spectral type of G6.5 for PZ Tel A. The extracted spectrum of the substellar companion, at a spatial position compatible with earlier orbit estimates, yields a temperature Teff = 2500-115+138 K, a visual extinction AV = 0.53-0.53+0.84 mag, a surface gravity of log g = 3.50-0.30+0.51 dex, and a metallicity at the edge of the grid of [M/H] = 0.30-0.30 dex. Conclusions: We derive a luminosity of log(Lbol/L⊙) = -2.66-0.08+0.06, a radius of R = 2.42-0.34+0.28 RJup, and a mass of M = 7.5-4.3+16.9 MJup for the PZ Tel companion, which is consistent with most earlier estimates using photometry alone. Combining our results with evolutionary models, we find a best-fitting mass of about 21 Jupiter masses at an age corresponding to the recently determined lithium depletion age of 7-2+4 Myr. Hence, the PZ Tel companion is most likely a wide brown dwarf companion in the 12-4+8 Myr old β Pic moving group. Based on observations made with ESO Telescopes at the La Silla Paranal Observatory under program ID 087

  13. Robotic observations of the most eccentric spectroscopic binary in the sky

    NASA Astrophysics Data System (ADS)

    Strassmeier, K. G.; Weber, M.; Granzer, T.

    2013-11-01

    Context. The visual A component of the Gliese 586AB system is a double-lined spectroscopic binary consisting of two cool stars with the exceptional orbital eccentricity of 0.976. Such an extremely eccentric system may be important for our understanding of low-mass binary formation. Aims: Precise stellar masses, ages, orbital elements, and rotational periods are a prerequisite for comparing stellar observations to angular-momentum evolution models. Methods: We present a total of 598 high-resolution échelle spectra from our robotic facility STELLA from 2006-2012, which we used to compute orbital elements of unprecedented accuracy. New Johnson VI photometry for the two visual components is also presented. Results: Our double-lined orbital solution for the A system has average velocity residuals for a measure of unit weight of 41 m s-1 for the G9V primary and 258 m s-1 for the M0V secondary, better by a factor ≈10 than the discovery orbit. The orbit constrains the eccentricity to 0.97608 ± 0.00004 and the orbital period to 889.8195 ± 0.0003 d. The masses of the two components are 0.87 ± 0.05 M⊙ and 0.58 ± 0.03 M⊙ if the inclination is 55 ± 1.5° as determined from adaptive-optics images, that is good to only 6% due to the error of the inclination, although the minimum masses reached a precision of 0.3%. The flux ratio Aa:Ab in the optical is between 30:1 in Johnson-B and 11:1 in I. Radial velocities of the visual B-component (K0-1V) appear constant to within 130 m s-1 over six years. Sinusoidal modulations of Teff of Aa with an amplitude of ≈55 K are seen with the orbital period. Component Aa appears warmest at periastron and coolest at apastron, indicating atmospheric changes induced by the high orbital eccentricity. No light variations larger than approximately 4 mmag are detected for A, while a photometric period of 8.5 ± 0.2 d with an amplitude of 7 mmag is discovered for the active star B, which we interpret to be its rotation period. We estimate an

  14. Astrometric and spectroscopic confirmation of a brown dwarf companion to GSC 08047-00232. VLT/NACO deep imaging and spectroscopic observations

    NASA Astrophysics Data System (ADS)

    Chauvin, G.; Lagrange, A.-M.; Lacombe, F.; Dumas, C.; Mouillet, D.; Zuckerman, B.; Gendron, E.; Song, I.; Beuzit, J.-L.; Lowrance, P.; Fusco, T.

    2005-02-01

    We report VLT/NACO imaging observations of the stars GSC 08047-00232 and HIP 6856, probable members of the large Tucana-Horologium association. During our previous ADONIS/SHARPII deep imaging survey, a substellar candidate companion was discovered around each star. Based on VLT/NACO astrometric measurements, we find that GSC 08047-00232 and the faint candidate companion near to it share the same proper motion with a significance of 3.1 σ. On the contrary, the candidate companion to HIP 6856 is probably a background object with a significance of 4.3 σ. We also detect a new fainter and closer candidate companion to HIP 6856, but which is likely a background object too with a significance of 4 σ. Recent VLT/NACO spectroscopic measurements of GSC 08047-00232 finally confirm the substellar nature of this young brown dwarf with a derived spectral type M 9.5±1. GSC 08047-00232 B, with an estimated mass of 25±10 MJup and an effective temperature of 2100±200 K, is presently the third substellar companion identified among young, nearby associations. Based on observations obtained at the VLT in ESO with programs 70.C-0677 and 072.C-0644.

  15. OPTICAL SPECTROSCOPIC OBSERVATIONS OF GAMMA-RAY BLAZAR CANDIDATES. IV. RESULTS OF THE 2014 FOLLOW-UP CAMPAIGN

    SciTech Connect

    Ricci, F.; Massaro, F.; Landoni, M.; D’Abrusco, R.; Milisavljevic, D.; Paggi, A.; Smith, Howard A.; Stern, D.; Masetti, N.; Tosti, G.

    2015-05-15

    The extragalactic γ-ray sky is dominated by the emission arising from blazars, one of the most peculiar classes of radio-loud active galaxies. Since the launch of Fermi several methods were developed to search for blazars as potential counterparts of unidentified γ-ray sources (UGSs). To confirm the nature of the selected candidates, optical spectroscopic observations are necessary. In 2013 we started a spectroscopic campaign to investigate γ-ray blazar candidates selected according to different procedures. The main goals of our campaign are: (1) to confirm the nature of these candidates, and (2) whenever possible, determine their redshifts. Optical spectroscopic observations will also permit us to verify the robustness of the proposed associations and check for the presence of possible source class contaminants to our counterpart selection. This paper reports the results of observations carried out in 2014 in the northern hemisphere with Kitt Peak National Observatory and in the southern hemisphere with the Southern Astrophysical Research telescopes. We also report three sources observed with the Magellan and Palomar telescopes. Our selection of blazar-like sources that could be potential counterparts of UGSs is based on their peculiar infrared colors and on their combination with radio observations both at high and low frequencies (i.e., above and below ∼1 GHz) in publicly available large radio surveys. We present the optical spectra of 27 objects. We confirm the blazar-like nature of nine sources that appear to be potential low-energy counterparts of UGSs. Then we present new spectroscopic observations of 10 active galaxies of uncertain type associated with Fermi sources, classifying all of them as blazars. In addition, we present the spectra for five known γ-ray blazars with uncertain redshift estimates and three BL Lac candidates that were observed during our campaign. We also report the case for WISE J173052.85−035247.2, candidate counterpart of the

  16. How Can Multi-Site Evaluations Be Participatory?

    ERIC Educational Resources Information Center

    Lawrenz, Frances; Huffman, Douglas

    2003-01-01

    Multi-site evaluations are becoming increasingly common in federal funding portfolios. Although much thought has been given to multi-site evaluation, there has been little emphasis on how it might interact with participatory evaluation. Therefore, this paper reviews several National Science Foundation educational, multi-site evaluations for the…

  17. Culture and Influence in Multisite Evaluation

    ERIC Educational Resources Information Center

    Kirkhart, Karen E.

    2011-01-01

    Understanding the influence of multisite evaluation requires careful consideration of cultural context. The author illustrates dimensions of influence and culture with excerpts from four National Science Foundation evaluation case studies and summarizes what influence teaches everyone about culture and what culture teaches everyone about…

  18. Spectroscopic observations of bright and dark emission features on the night side of venus.

    PubMed

    Bell, J F; Crisp, D; Lucey, P G; Ozoroski, T A; Sinton, W M; Willis, S C; Campbell, B A

    1991-05-31

    Near-infrared spectra of a bright and a dark thermal emission feature on the night side of Venus have been obtained from 2.2 to 2.5 micrometers (microm) at a spectral resolution of 1200 to 1500. Both bright and dark features show numerous weak absorption bands produced by CO(2), CO, water vapor, and other gases. The bright feature (hot spot) emits more radiation than the dark feature (cold spot) throughout this spectral region, but the largest contrasts occur between 2.21 and 2.32 microm, where H(2)SO(4) clouds and a weak CO(2) band provide the only known sources of extinction. The contrast decreases by 55 to 65 percent at wavelengths longer than 2.34 microm, where CO, clouds, and water vapor also absorb and scatter upwelling radiation. This contrast reduction may provide direct spectroscopic evidence for horizontal variations in the water vapor concentrations in the Venus atmosphere at levels below the cloud tops. PMID:17842954

  19. Spectroscopic observations of bright and dark emission features on the night side of venus.

    PubMed

    Bell, J F; Crisp, D; Lucey, P G; Ozoroski, T A; Sinton, W M; Willis, S C; Campbell, B A

    1991-05-31

    Near-infrared spectra of a bright and a dark thermal emission feature on the night side of Venus have been obtained from 2.2 to 2.5 micrometers (microm) at a spectral resolution of 1200 to 1500. Both bright and dark features show numerous weak absorption bands produced by CO(2), CO, water vapor, and other gases. The bright feature (hot spot) emits more radiation than the dark feature (cold spot) throughout this spectral region, but the largest contrasts occur between 2.21 and 2.32 microm, where H(2)SO(4) clouds and a weak CO(2) band provide the only known sources of extinction. The contrast decreases by 55 to 65 percent at wavelengths longer than 2.34 microm, where CO, clouds, and water vapor also absorb and scatter upwelling radiation. This contrast reduction may provide direct spectroscopic evidence for horizontal variations in the water vapor concentrations in the Venus atmosphere at levels below the cloud tops.

  20. Thermal treatment effects imposed on solid DNA cationic lipid complex with hexadecyltrimethylammonium chloride, observed by variable angle spectroscopic ellipsometry

    SciTech Connect

    Nizioł, Jacek

    2014-12-21

    DNA cationic lipid complexes are materials of properties required for applications in organic electronics and optoelectronics. Often, their thermal stability demonstrated by thermogravimetry is cited in the literature as important issue. However, little is known about processes occurring in heated solid DNA cationic lipid complexes. In frame of this work, thin films of Deoxyribonucleic acid-hexadecyltrimethylammonium chloride (DNA-CTMA) were deposited on silicon wafers. Samples were thermally annealed, and simultaneously, their optical functions were measured by spectroscopic ellipsometry. At lower temperatures, thermal expansion coefficient of solid DNA-CTMA was negative, but at higher temperatures positive. Thermally induced modification of absorption spectrum in UV-vis was observed. It occurred at a range of temperatures higher than this of DNA denaturation in solution. The observed phenomenon was irreversible, at least in time scale of the experiment (one day)

  1. OPTICAL SPECTROSCOPIC OBSERVATIONS OF γ-RAY BLAZAR CANDIDATES. III. THE 2013/2014 CAMPAIGN IN THE SOUTHERN HEMISPHERE

    SciTech Connect

    Landoni, M.; Massaro, F.; Paggi, A.; D’Abrusco, R.; Milisavljevic, D.; Smith, H. A.; Masetti, N.; Tosti, G.; Chomiuk, L.; Strader, J.; Cheung, C. C.

    2015-05-15

    We report the results of our exploratory program carried out with the southern Astrophysical Research telescope aimed at associating counterparts and establishing the nature of the Fermi Unidentified γ-ray Sources (UGSs). We selected the optical counterparts of six UGSs from the Fermi catalog on the basis of our recently discovered tight connection between infrared and γ-ray emission found for the γ-ray blazars detected by the Wide-Field Infrared Survey Explorer in its all-sky survey. We perform for the first time a spectroscopic study of the low-energy counterparts of the Fermi UGSs, in the optical band, confirming the blazar-like nature of the whole sample. We also present new spectroscopic observations of six active galaxies of uncertain type associated with Fermi sources which appear to be BL Lac objects. Finally, we report the spectra collected for six known γ-ray blazars belonging to the Roma BZCAT that were obtained to establish their nature or better estimate their redshifts. Two interesting cases of high redshift and extremely luminous BL Lac objects (z ≥ 1.18 and z ≥ 1.02, based on the detection of Mg ii intervening systems) are also discussed.

  2. Bias and Bias Correction in Multisite Instrumental Variables Analysis of Heterogeneous Mediator Effects

    ERIC Educational Resources Information Center

    Reardon, Sean F.; Unlu, Fatih; Zhu, Pei; Bloom, Howard S.

    2014-01-01

    We explore the use of instrumental variables (IV) analysis with a multisite randomized trial to estimate the effect of a mediating variable on an outcome in cases where it can be assumed that the observed mediator is the only mechanism linking treatment assignment to outcomes, an assumption known in the IV literature as the exclusion restriction.…

  3. Bias and Bias Correction in Multi-Site Instrumental Variables Analysis of Heterogeneous Mediator Effects

    ERIC Educational Resources Information Center

    Reardon, Sean F.; Unlu, Faith; Zhu, Pei; Bloom, Howard

    2013-01-01

    We explore the use of instrumental variables (IV) analysis with a multi-site randomized trial to estimate the effect of a mediating variable on an outcome in cases where it can be assumed that the observed mediator is the only mechanism linking treatment assignment to outcomes, as assumption known in the instrumental variables literature as the…

  4. Optical Spectroscopic Observations of γ-Ray Blazar Candidates. III. The 2013/2014 Campaign in the Southern Hemisphere

    NASA Astrophysics Data System (ADS)

    Landoni, M.; Massaro, F.; Paggi, A.; D'Abrusco, R.; Milisavljevic, D.; Masetti, N.; Smith, H. A.; Tosti, G.; Chomiuk, L.; Strader, J.; Cheung, C. C.

    2015-05-01

    We report the results of our exploratory program carried out with the southern Astrophysical Research telescope aimed at associating counterparts and establishing the nature of the Fermi Unidentified γ-ray Sources (UGSs). We selected the optical counterparts of six UGSs from the Fermi catalog on the basis of our recently discovered tight connection between infrared and γ-ray emission found for the γ-ray blazars detected by the Wide-Field Infrared Survey Explorer in its all-sky survey. We perform for the first time a spectroscopic study of the low-energy counterparts of the Fermi UGSs, in the optical band, confirming the blazar-like nature of the whole sample. We also present new spectroscopic observations of six active galaxies of uncertain type associated with Fermi sources which appear to be BL Lac objects. Finally, we report the spectra collected for six known γ-ray blazars belonging to the Roma BZCAT that were obtained to establish their nature or better estimate their redshifts. Two interesting cases of high redshift and extremely luminous BL Lac objects (z ≥ 1.18 and z ≥ 1.02, based on the detection of Mg ii intervening systems) are also discussed. Based on observations obtained at the southern Astrophysical Research (SOAR) telescope, which is a joint project of the Ministério da Ciência, Tecnologia, e Inovação (MCTI) da República Federativa do Brasil, the U.S. National Optical Astronomy Observatory (NOAO), the University of North Carolina at Chapel Hill (UNC), and Michigan State University (MSU).

  5. Spectroscopic Observations of Steep Spectrum Narrow-Line Seyfert 1 Galaxies

    NASA Technical Reports Server (NTRS)

    Leighly, Karen

    1999-01-01

    ROSAT observations of narrow-line Seyfert 1s found consistently steep spectra and rapid variability, but ASCA observations show more diversity, very different to classical Seyfert 1s. However, in 3 NLS1s, ASCA finds common characteristics of these exciting new class of AGN (active galactic nuclei): a very strong high temperature soft excess, weak hard tail, a possible blue shifted ionized oxygen edge, and rapid large amplitude variability characterized by flares and quiescent periods. It is necessary to observe many more such objects in order to understand the physical processes underlying the different phenomenology in ASCA. ASCA observations of two NLS1s discovered by ROSAT's all sky survey were proposed and an observation of one of these objects, RX J0439-45, was awarded. The results of spectral and variability analysis are included in Leighly 1999ab, and preliminary results are found in Leighly 1998ab.

  6. An Overview of Ultraviolet Through Infrared Reflectance Spectroscopic Observations of Mercury During the First MESSENGER Flyby

    NASA Astrophysics Data System (ADS)

    Izenberg, N. R.; McClintock, W. E.; Holsclaw, G. M.; Robinson, M. S.; Blewett, D. T.; Domingue, D. L.; Head, J. W.; Jensen, E. A.; Kochte, M. C.; Lankton, M. R.; Murchie, S. L.; Sprague, A. L.; Vilas, F.; Solomon, S. C.

    2008-05-01

    During the first MESSENGER flyby of Mercury on January 14, 2008, the Mercury Atmospheric and Surface Composition Spectrometer (MASCS) measured reflectance spectra from Mercury's surface over the wavelength range 220-1450 nm. These are the first high-spatial-resolution (<10 km) spectra at any wavelength and the first reported ultraviolet (UV, wavelength < 360 nm) observations of the surface. MASCS observed the sunlit surface for approximately 14 minutes after closest approach, acquiring over 650 spectra with the Visible and Infrared Spectrograph (VIRS) detectors of MASCS sensitive to wavelengths of 350-1450 nm. MASCS also obtained just under four grating scans in the middle ultraviolet (220-320 nm) using MASCS's Ultraviolet and Visible Spectrometer (UVVS) component. Most of the near-equatorial ground track of the observation covered terrain in the previously unseen hemisphere of Mercury but also crossed into the hemisphere viewed by Mariner 10 south of Mozart crater and in Tir Planitia. Ground-based observations of Mercury reveal a surface with a red, nearly featureless spectrum in the visible and near-infrared (wavelengths greater than ~ 500 nm) that has been interpreted as evidence for a largely iron-poor feldspathic composition. Initial analyses of VIRS spectra also show strongly red-sloped, near featureless spectra, appearing to support contentions of low iron abundance in surface materials. However, interpretation of Mercury's spectral reflectance is complicated by our lack of knowledge about the effects on its surface materials of space weathering, which both suppresses the strength of spectral absorption features and reddens the spectrum. Brightness variations and absorption bands in ultraviolet reflectance may help determine both the nature and extent of processes that modify observed reflectance at longer wavelengths. MASCS surface observation data demonstrate spectral variations across the Mercury surface that can be related to previous telescopic

  7. Detection of High-Frequency Oscillations and Damping from Multi-slit Spectroscopic Observations of the Corona

    NASA Astrophysics Data System (ADS)

    Samanta, T.; Singh, J.; Sindhuja, G.; Banerjee, D.

    2016-01-01

    During the total solar eclipse of 11 July 2010, multi-slit spectroscopic observations of the solar corona were performed from Easter Island, Chile. To search for high-frequency waves, observations were taken at a high cadence in the green line at 5303 Å that is due to [Fe xiv] and the red line at 6374 Å that is due to [Fe x]. The data were analyzed to study the periodic variations in intensity, Doppler velocity, and line width using wavelet analysis. The data with high spectral and temporal resolution enabled us to study the rapid dynamical changes within coronal structures. We find that at certain locations, each parameter shows significant oscillation with periods ranging from 6 - 25 s. For the first time, we were able to detect damping of high-frequency oscillations with periods of about 10 s. If the observed damped oscillations are due to magnetohydrodynamic waves, then they can contribute significantly to the heating of the corona. From a statistical study we try to characterize the nature of the observed oscillations while considering the distribution of power in different line parameters.

  8. Time Series Spectroscopic and Photometric Observations of the Massive DAV BPM 37093

    NASA Astrophysics Data System (ADS)

    Nitta, Atsuko; Kepler, S. O.; Chene, Andre–Nicolas; Koester, D.; Provencal, J. L.; Sullivan, D. J.; Chote, Paul; Safeko, Ramotholo; Kanaan, Antonio; Romero, Alejandra; Corti, Mariela; Corti, Mariela; Kilic, Mukremin; Winget, D. E.

    2015-06-01

    BPM 37093 was the first of only a handful of massive (1.05+/-0.05 M⊙; Bergeron 2004;Koester & Allard 2000) white dwarf pulsators discovered (Kanaan et al. 1992). These stars are particularly interesting because the crystallized mass-fraction as a function of mass and temperature is poorly constrained by observation, yet this process adds 1-2 Gyr uncertainty in ages of the oldest white dwarf stars observed and hence, in the ages of associations that contain them (Abrikosov 1960; Kirzhnits 1960; Salpeter 1961). Last year, we discovered that ESO uses BPM 37093 as a standard star and extracted corresponding spectra from the public archive. The data suggested a large variation in the observed hydrogen line profiles that could potentially be due to pulsations, but the measurement did not reach a detection-quality threshold. To further explore this possibility, though, we obtained 4hrs of continuous time series spectroscopy of BPM 37093 with Gemini in the Northern Spring of 2014. We present our preliminary results from these data along with those from the accompanying time series photometric observations we gathered from Mt. John (New Zealand), South African Astronomical Observatory (SAAO), Panchromatic Robotic optical Monitoring and Polarimetry Telescopes (PROMPT) in Chile, and Complejo Astronomico El Leoncito (Argentina) to support the Gemini observations.

  9. Spatially Resolved Spectroscopic Observations of Na and K in the Tail of Comet C/2011 L4 (PanSTARRS)

    NASA Astrophysics Data System (ADS)

    Cochran, Anita L.; Wooden, D. H.; McKay, A. J.; Cauzzi, G.; Reardon, K.; Tozzi, G.

    2013-10-01

    We used the Dunn Solar Telescope (DST) of The National Solar Observatory to obtain spectroscopic observations of comet C/2011 L4 (PanSTARRS) on 13 and 14 March 2013. The DST has the advantage for comet observations that one can observe the comet when it is close to the Sun. At the time of our observations, comet PanSTARRS was at 0.31 and 0.32 AU heliocentric distance. We used the Horizontal Spectrograph to observe five different spectral regions of the coma. The resolving power was 50,000 - 60,000. The slit was 0.3 arcsec wide and 171 arcsec long. At the comet's geocentric distance, the slit covered 1.43e5 km. The comet was approximately centered on the slit. We observed strong emissions from sodium (D1@589.592nm and D2@588.995nm) and potassium (D1@770.108nm and D2@671.701nm), along with a weak continuum. Lithium was not detected. The sodium was visible on the optocenter and the tailward side of the comet and extended to the edge of the slit (i.e. at least 70,000km tailward). It shifted redward at larger cometocentric distances, attributable to the acceleration of sodium by solar radiation pressure. The potassium was much weaker than the sodium and does not appear to extend as far from the optocenter. In this paper, we will show the distribution of these gases and compare their relative strengths. We will discuss the effects of the different photodissociative lifetimes of sodium and potassium and how they dictate what we observed.

  10. The composition of M-type asteroids: Synthesis of spectroscopic and radar observations

    NASA Astrophysics Data System (ADS)

    Neeley, J. R.; Ockert-Bell, M. E.; Clark, B. E.; Shepard, M. K.; Cloutis, E. A.; Fornasier, S.; Bus, S. J.

    2011-10-01

    This work updates our and expands our long term radar-driven observational campaign of 27 main-belt asteroids (MBAs) focused on Bus-DeMeo Xc- and Xk-type objects (Tholen X and M class asteroids) using the Arecibo radar and NASA Infrared Telescope Facilities (IRTF). Seventeen of our targets were near-simultaneously observed with radar and those observations are described in companion paper (Shepard et al., 2010). We utilized visible wavelength for a more complete compositional analysis of our targets. Compositional evidence is derived from our target asteroid spectra using three different methods: 1) a χ2 search for spectral matches in the RELAB database, 2) parametric comparisons with meteorites and 3) linear discriminant analysis. This paper synthesizes the results of the RELAB search, parametric comparisons, and linear discriminant analysis with compositional suggestions based on radar observations. We find that for six of seventeen targets with radar data, our spectral results are consistent with their radar analog (16 Psyche, 21 Lutetia, 69 Hesperia, 135 Hertha, 216 Kleopatra, and 497 Iva). For twenty out of twenty-seven objects our statistical comparisons with RELAB meteorites result in consistent analog identification, providing a degree of confidence in our parametric methods.

  11. IN-SITU SEQUESTRATION OF ZINC: SPECTROSCOPIC OBSERVATIONS FROM A FIELD STUDY

    EPA Science Inventory

    Zinc concentrations in the soil and groundwater at the Indian Head Naval Warfare Center, located in Charles County Maryland, have been observed at levels exceeding 20 g/kg and 25 mg/L respectively due to the operation of a zinc recovery furnace during WWI. Erosion of the site due...

  12. Spectroscopic observations of the Uranus' satellite Miranda in Near-IR

    NASA Astrophysics Data System (ADS)

    Gourgeot, F.; Dumas, C.; Merlin, F.; Vernazza, P.; Alvarez-Candal, A.

    2013-09-01

    We present new Near-IR spectra of the Uranus' icy satellite Miranda. This body is probably the most remarkable of all satellites of Uranus, displaying series of surface features such as faults, craters and largescale upwelling, remnant of a geologically very active past. The observations were performed first at the Palomar Observatory with the PHARO instrument (Palomar High Angular Resolution Observer) and then at the Mauna Kea Observatory with SpeX instrument based on the IRTF (Infra-Red Telescope Facility). Water ice is clearly visible in K-band (large 2.0 μm absorption band) and crystalline water ice (at 1.65 μm) seems to cover the most part of the satellite's surface. We focused the study in H band on the 1.42-1.72 μm range at observations dates corresponding to the leading and trailing hemispheres of Miranda. Contrary to the other outer Uranus' moons (Grundy et al. 2006), we did not found any significative differences between both hemispheres in this spectral range. We also studied the possible presence of volatiles like ammonia hydrate and do not exclude the possible presence of a tiny 2.22 μm band yet observed by Bauer et al. 2002. No significant features of carbon dioxide were identified on any spectra. We performed spectral models, based on bi-hemispherical reflectance theory (Hapke 1993) in order to obtain more details on the chemical compounds possibly present on the surface of this Uranian satellite.

  13. Non-LTE Inversion of Spectropolarimetric and Spectroscopic Observations of a Small Active-region Filament Observed at the VTT

    NASA Astrophysics Data System (ADS)

    Schwartz, P.; Balthasar, H.; Kuckein, C.; Koza, J.; Gömöry, P.; Rybák, J.; Kučera, A.; Heinzel, P.

    2016-04-01

    An active region mini-filament was observed by VTT simultaneously in the HeI 10 830 Å triplet by the TIP 1 spectropolarimeter, in Hα by the TESOS Fabry-Pérot interferometer, and in Ca II 8542 Å by the VTT spectrograph. The spectropolarimetric data were inverted using the HAZEL code and Hα profiles were modelled solving a NLTE radiative transfer in a simple isobaric and isothermal 2D slab irradiated both from bottom and sides. It was found that the mini-filament is composed of horizontal fluxtubes, along which the cool plasma of T˜10 000 K can flow by very large - even supersonic - velocities.

  14. The composition of M-type asteroids II: Synthesis of spectroscopic and radar observations

    NASA Astrophysics Data System (ADS)

    Neeley, J. R.; Clark, B. E.; Ockert-Bell, M. E.; Shepard, M. K.; Conklin, J.; Cloutis, E. A.; Fornasier, S.; Bus, S. J.

    2014-08-01

    This work updates and expands on results of our long-term radar-driven observational campaign of main-belt asteroids (MBAs) focused on Bus-DeMeo Xc- and Xk-type objects (Tholen X and M class asteroids) using the Arecibo radar and NASA Infrared Telescope Facilities (Ockert-Bell, M.E., Clark, B.E., Shepard, M.K., Rivkin, A.S., Binzel, R.P., Thomas, C.A., DeMeo, F.E., Bus, S.J., Shah, S. [2008]. Icarus 195, 206-219; Ockert-Bell, M.E., Clark, B.E., Shepard, M.K., Issacs, R.A., Cloutis, E.A., Fornasier, S., Bus, S.J. [2010]. Icarus 210, 674-692; Shepard, M.K. et al. [2008a]. Icarus 193, 20-38; Shepard, M.K. et al. [2008b]. Icarus 195, 184-205; Shepard, M.K. et al. [2010]. Icarus 215, 547-551). Eighteen of our targets were near-simultaneously observed with radar and those observations are described in Shepard et al. (Shepard, M.K. et al. [2010]. Icarus 215, 547-551). We combine our near-infrared data with available visible wavelength data for a more complete compositional analysis of our targets. Compositional evidence is derived from our target asteroid spectra using two different methods, a χ2 search for spectral matches in the RELAB database and parametric comparisons with meteorites. We present four new methods of parametric comparison, including discriminant analysis. Discriminant analysis identifies meteorite type with 85% accuracy. This paper synthesizes the results of these two analog search algorithms and reconciles those results with analogs suggested from radar data (Shepard, M.K. et al. [2010]. Icarus 215, 547-551). We have observed 29 asteroids, 18 in conjunction with radar observations. For eighteen out of twenty-nine objects observed (62%) our compositional predictions are consistent over two or more methods applied. We find that for our Xc and Xk targets the best fit is an iron meteorite for 34% of the samples. Enstatite chondrites were best fits for 6 of our targets (21%). Stony-iron meteorites were best fits for 2 of our targets (7%). A discriminant

  15. REACTION DYNAMICS. Spectroscopic observation of resonances in the F + H2 reaction.

    PubMed

    Kim, Jongjin B; Weichman, Marissa L; Sjolander, Tobias F; Neumark, Daniel M; Kłos, Jacek; Alexander, Millard H; Manolopoulos, David E

    2015-07-31

    Photodetachment spectroscopy of the FH2(-) and FD2(-) anions allows for the direct observation of reactive resonances in the benchmark reaction F + H2 → HF + H. Using cooled anion precursors and a high-resolution electron spectrometer, we observe several narrow peaks not seen in previous experiments. Theoretical calculations, based on a highly accurate F + H2 potential energy surface, convincingly assign these peaks to resonances associated with quasibound states in the HF + H and DF + D product arrangements and with a quasibound state in the transition state region of the F + H2 reaction. The calculations also reveal quasibound states in the reactant arrangement, which have yet to be resolved experimentally.

  16. Evidence for CO in Jupiter's atmosphere from airborne spectroscopic observations at 5 microns

    NASA Technical Reports Server (NTRS)

    Larson, H. P.; Fink, U.; Treffers, R. R.

    1978-01-01

    High-altitude (12.4 km) spectra of Jupiter recorded at the Kuiper Airborne Observatory are analyzed for the presence of CO absorption lines. A line-by-line comparison of Jupiter's spectrum with that of carbon monoxide is presented, as well as a correlation analysis that includes the influence of other gases present in Jupiter's atmosphere (CH4, NH3, H2O, PH3, and GeH4). The resulting evidence points strongly to the presence of carbon monoxide in Jupiter's atmosphere, thus strengthening Beer's evidence for it. Possible explanations for the existence and observability of Jovian CO, including convection from hotter, deeper layers or decomposition of organic molecules, are explored. A recent suggestion that the Jovian CO is restricted to stratospheric levels is not supported by the observations.

  17. Spectroscopic observations of the displacement dynamics of physically adsorbed molecules-CO on C60

    NASA Astrophysics Data System (ADS)

    Yuan, Chunqing; Yates, John T.

    2016-10-01

    In this paper, we observed physically adsorbed CO molecules on C60 surface being displaced by impinging noble gas atoms (He, Ne, Ar, Kr), either through a dynamic displacement process or an exothermic replacement process, depending on their adsorption energies. This displacement mechanism could shift from one to the other depending on the surface coverage and temperature. Furthermore, rotational energy of the impinging molecules may also contribute to the dynamic displacement process by supplying additional energy.

  18. Impact of Spectroscopic Line Parameters on Carbon Monoxide Column Density Retrievals from Shortwave Infrared Nadir Observations

    NASA Astrophysics Data System (ADS)

    Schmidt, Denise; Gimeno Garcia, Sebastian; Schreier, Franz; Lichtenberg, Gunter

    2015-06-01

    Among the various input data required for the retrieval of atmospheric state parameters from infrared remote sensing observations molecular spectroscopy line data have a central role, because their quality is critical for the quality of the final product. Here we discuss the impact of the line parameters on vertical column densities (VCD) estimated from short wave infrared nadir observations. Using BIRRA (the Beer InfraRed Retrieval Algorithm) comprising a line-by-line radiative transfer code (forward model) and a separable nonlinear least squares solver for inversion we retrieve carbon monoxide from observations of SCIAMACHY aboard Envisat. Retrievals using recent versions of HITRAN und GEISA have been performed and the results are compared in terms of residual norms, molecular density scaling factors, their corresponding errors, and the final VCD product. The retrievals turn out to be quite similar for all three databases, so a definite recommendation in favor of one of these databases is difficult for the considered spectral range around 2:3 μm . Nevertheless, HITRAN 2012 appears to be advantageous when evaluating the different quality criteria.

  19. HST spectroscopic observations of Jupiter after the collision of comet Shoemaker-Levy 9.

    PubMed

    Noll, K S; McGrath, M A; Trafton, L M; Atreya, S K; Caldwell, J J; Weaver, H A; Yelle, R V; Barnet, C; Edgington, S

    1995-03-01

    Ultraviolet spectra obtained with the Hubble Space Telescope identified at least 10 molecules and atoms in the perturbed stratosphere near the G impact site, most never before observed in Jupiter. The large mass of sulfur-containing material, more than 10(14) grams in S2 alone, indicates that many of the sulfur-containing molecules S2, CS2, CS, H2S, and S+ may be derived from a sulfur-bearing parent molecule native to Jupiter. If so, the fragment must have penetrated at least as deep as the predicted NH4SH cloud at a pressure of approximately 1 to 2 bars. Stratospheric NH3 was also observed, which is consistent with fragment penetration below the cloud tops. Approximately 10(7) grams of neutral and ionized metals were observed in emission, including Mg II, Mg I, Si I, Fe I, and Fe II. Oxygen-containing molecules were conspicuous by their absence; upper limits for SO2, SO, CO, SiO, and H2O are derived.

  20. SPECTROSCOPIC OBSERVATIONS OF PLANETARY NEBULAE IN THE NORTHERN SPUR OF M31

    SciTech Connect

    Fang, X.; Liu, X.-W.; Zhang, Y.; Garcia-Benito, R.

    2013-09-10

    We present spectroscopy of three planetary nebulae (PNe) in the Northern Spur of the Andromeda galaxy (M31) obtained with the Double Spectrograph on the 5.1 m Hale Telescope at the Palomar Observatory. The samples were selected from the observations of Merrett et al. Our purpose is to investigate the formation of the substructures of M31 using PNe as a tracer of chemical abundances. The [O III] {lambda}4363 line is detected in the spectra of two objects, enabling temperature determinations. Ionic abundances are derived from the observed collisionally excited lines, and elemental abundances of nitrogen, oxygen, neon, sulfur, and argon are estimated. We study the correlations between oxygen and the {alpha}-element abundance ratios using our sample and the M31 disk and bulge PNe from the literature. In one of the three PNe, we observed a relatively higher oxygen abundance compared to the disk sample of M31 at similar galactocentric distances. The results of at least one of the three Northern Spur PNe might be in line with the proposed possible origin of the Northern Spur substructure of M31, i.e., the Northern Spur is connected to the Southern Stream and both substructures comprise the tidal debris of the satellite galaxies of M31.

  1. The composition of M-type asteroids: Synthesis of spectroscopic and radar observations

    NASA Astrophysics Data System (ADS)

    Ockert-Bell, M. E.; Clark, B. E.; Shepard, M. K.; Isaacs, R. A.; Cloutis, E. A.; Fornasier, S.; Bus, S. J.

    2010-12-01

    We have conducted a radar-driven observational campaign of 22 main-belt asteroids (MBAs) focused on Bus-DeMeo Xc- and Xk-type objects (Tholen X and M class asteroids) using the Arecibo radar and NASA Infrared Telescope Facilities (IRTF). Sixteen of our targets were near-simultaneously observed with radar and those observations are described in a companion paper (Shepard, M.K., and 19 colleagues [2010]. Icarus, in press). We find that most of the highest metal-content asteroids, as suggested by radar, tend to exhibit silicate absorption features at both 0.9 and 1.9 μm, and the lowest metal-content asteroids tend to exhibit either no bands or only the 0.9 μm band. Eleven of the asteroids were observed at several rotational longitudes in the near-infrared and significant variations in continuum slope were found for nine in the spectral regions 1.1-1.45 μm and 1.6-2.3 μm. We utilized visible wavelength data (Bus, S.J., Binzel, R.P. [2002b]. Icarus 158, 146-177; Fornasier, S., Clark, B.E., Dotto, E., Migliorini, A., Ockert-Bell, M., Barucci, M.A. [2010]. Icarus 210, 655-673.) for a more complete compositional analysis of our targets. Compositional evidence is derived from our target asteroid spectra using two different methods: (1) a χ2 search for spectral matches in the RELAB database, and (2) parametric comparisons with meteorites. This paper synthesizes the results of the RELAB search and the parametric comparisons with compositional suggestions based on radar observations. We find that for six of the seven asteroids with the highest iron abundances, our spectral results are consistent with the radar evidence (16 Psyche, 216 Kleopatra, 347 Pariana, 758 Mancunia, 779 Nina, and 785 Zwetana). Three of the seven asteroids with the lowest metal abundances, our spectral results are consistent with the radar evidence (21 Lutetia, 135 Hertha, 497 Iva). The remaining seven asteroids (22 Kalliope, 97 Klotho, 110 Lydia, 129 Antigone, 224 Oceana, 678 Fredegundis, and 771

  2. Mass spectroscopic observation of shock-induced chemistry in liquid CS2.

    PubMed

    Engelke, Ray; Blais, Normand C; Sheffield, Stephen A

    2008-01-10

    We have observed, via time-of-flight mass spectrometry, 13 chemical species more massive than CS2 produced by shocking liquid CS2 to very high pressure/temperature. The stoichiometry of three of these species is uniquely determined from the 12CS2 experiments; these species are C2S2, C3S2, and C4S2. The stoichiometry of the other 10 structures cannot be uniquely determined from 12CS2 experiments. However, by redoing the experiments using isotopically labeled CS2 (i.e., 13CS2), we determined the stoichiometry of nine of the remaining structures. The nine structures are Sn (n = 3-8) and CS3, C2S5, and C4S6. A structure with mass 297.1 amu was also observed in the 12CS2 experiments but was not detected in the 13CS2 experiments. This structure must be C6S7, C14S4, or C22S; given the low carbon content of the other observed carbon species, it is probably C6S7. The shockwaves to which the CS2 molecules were subjected were produced by the detonation of high mass-density solid explosives. The explosives used were either a plastic bonded form of cyclotetramethlylene tetranitramine or pure hexanitrostilbene. Numerical compressible fluid-mechanical simulations were done to estimate the pressures, temperatures, and time scales of the processes that occurred in the shocked CS2. The results obtained in the present experiments are related to earlier work on CS2's chemical reactivity that used both shockwave methods and static techniques to produce very high pressure.

  3. The Composition of M-type Asteroids: Synthesis of Spectroscopic and Radar Observations.

    NASA Astrophysics Data System (ADS)

    Bell, Maureen; Clark, B. E.; Shepard, M. K.; Issacs, R. A.; Cloutis, E. A.; Fornasier, S.; Bus, S. J.

    2010-10-01

    We have conducted a radar-driven observational campaign of 22 main-belt asteroids (MBAs) focused on Bus-DeMeo Xc- and Xk-type objects (Tholen X and M class asteroids) using the Arecibo radar and NASA Infrared Telescope Facilities (IRTF). Sixteen of our targets were near-simultaneously observed with radar. We find that most of the highest metal-content asteroids, as suggested by radar, tend to exhibit silicate absorption features at both 0.9 and 1.9 microns, and the lowest metal-content asteroids tend to exhibit either no bands or only the 0.9 microns band. Eleven of the asteroids were observed at several rotational longitudes in the near-infrared and significant variations in continuum slope were found for nine in the spectral regions 1.1-1.45 microns and 1.6-2.3 microns. Compositional evidence is derived from our target asteroid spectra using two different methods: 1) a Chi-squared search for spectral matches in the RELAB database, and 2) parametric comparisons with meteorites. We find that for four of the seven asteroids with the highest iron abundances, our spectral results are consistent with each other and with the radar evidence pointing to an iron meteorite composition (16 Psyche, 216 Kleopatra, 347 Pariana, and 779 Nina). Four asteroids have radar analogs consistent with either our parametric comparison or our RELAB analog type (21 Lutetia, 135 Hertha, 497 Iva, and 758 Mancunia ). The remaining eight asteroids (22 Kalliope, 97 Klotho, 110 Lydia, 129 Antigone, 224 Oceana, 678 Fredegundis, 771 Libera, and 785 Zwetana) have ambiguous compositional interpretations when comparing the spectral analogs to the radar analogs.

  4. The solar-like CoRoT target HD 170987: spectroscopic and seismic observations

    NASA Astrophysics Data System (ADS)

    Mathur, S.; García, R. A.; Catala, C.; Bruntt, H.; Mosser, B.; Appourchaux, T.; Ballot, J.; Creevey, O. L.; Gaulme, P.; Hekker, S.; Huber, D.; Karoff, C.; Piau, L.; Régulo, C.; Roxburgh, I. W.; Salabert, D.; Verner, G. A.; Auvergne, M.; Baglin, A.; Chaplin, W. J.; Elsworth, Y.; Michel, E.; Samadi, R.; Sato, K.; Stello, D.

    2010-07-01

    Context. The CoRoT mission is in its third year of observation and the data from the second long run in the galactic centre direction are being analysed. The solar-like oscillating stars that have been observed up to now have given some interesting results, specially concerning the amplitudes that are lower than predicted. We present here the results from the analysis of the star HD 170987. Aims: The goal of this research work is to characterise the global parameters of HD 170987. We look for global seismic parameters such as the mean large separation, maximum amplitude of the modes, and surface rotation because the signal-to-noise ratio in the observations does not allow us to measure individual modes. We also aim to retrieve the parameters of the star and its chemical composition. Methods: We studied the chemical composition of the star through ground-based observations performed with the NARVAL spectrograph. We used several methods to calculate the global parameters from the acoustic oscillations based on CoRoT data. The light curve of the star has been interpolated with inpainting algorithms to reduce the effect of data gaps. Results: We found the power excess related to p modes in the range [400-1200] μHz with a mean large separation of 55.2 ± 0.8 μHz with a probability above 95 % that increases to 55.9 ± 0.2 μHz in a higher frequency range [500-1250] μHz and a rejection level of 1%. A hint of the variation of this quantity with frequency was also found. The rotation period of the star is estimated to be around 4.3 days with an inclination axis of i = 50° +20-13. We measured a bolometric amplitude per radial mode in a range [2.4-2.9] ppm around 1000 μHz. Finally we estimate the stellar mass with a grid of models, M = 1.43 ± 0.05 M_⊙, the radius, R = 1.96 ± 0.046 R_⊙, and the age ~2.4 Gyr. The CoRoT space mission, launched on 2006 December 27, has been developed and is operated by CNES, with the contribution of Austria, Belgium, Brazil, ESA (RSSD

  5. Spectroscopic observations of the candidate star coincident with A0620-00

    NASA Technical Reports Server (NTRS)

    Gull, T. R.; Henize, K. G.; York, D. G.; Snow, T. P., Jr.

    1976-01-01

    Several spectra of the optical object identified with the X-ray flare source A0620-00 have been obtained at 5 A/mm with the Cassegrain echelle spectrograph on the 4-m Mayall telescope at Kitt Peak National Observatory. These spectra reveal no significant stellar lines, but the flux distribution in the range 4250-7400 A, dereddened for a color excess of 0.9 mag, is similar to that of an O star. The color excess, which is derived from the observed strength of the 5780-A diffuse interstellar band, and the velocities and strengths of the interstellar Na I D lines imply that the object is between 1.5 and 2.5 kpc from the sun. If a distance of 2 kpc is adopted, then the luminosity of the source in the observed wavelength region is roughly 5 by 10 to the 35th power erg/s. The possibility that this object is a slow nova is discussed.

  6. Imaging and spectroscopic observations of a filament channel and the implications for the nature of counter-streamings

    SciTech Connect

    Chen, P. F.; Fang, C.; Harra, L. K.

    2014-03-20

    The dynamics of a filament channel are observed with imaging and spectroscopic telescopes before and during the filament eruption on 2011 January 29. The extreme ultraviolet (EUV) spectral observations reveal that there are no EUV counterparts of the Hα counter-streamings in the filament channel, implying that the ubiquitous Hα counter-streamings found by previous research are mainly due to longitudinal oscillations of filament threads, which are not in phase between each other. However, there exist larger-scale patchy counter-streamings in EUV along the filament channel from one polarity to the other, implying that there is another component of unidirectional flow (in the range of ±10 km s{sup –1}) inside each filament thread in addition to the implied longitudinal oscillation. Our results suggest that the flow direction of the larger-scale patchy counter-streaming plasma in the EUV is related to the intensity of the plage or active network, with the upflows being located at brighter areas of the plage and downflows at the weaker areas. We propose a new method to determine the chirality of an erupting filament on the basis of the skewness of the conjugate filament drainage sites. This method suggests that the right-skewed drainage corresponds to sinistral chirality, whereas the left-skewed drainage corresponds to dextral chirality.

  7. The "Cool Algol" BD+05 706 : Photometric observations of a new eclipsing double-lined spectroscopic binary

    NASA Astrophysics Data System (ADS)

    Marschall, L. A.; Torres, G.; Neuhauser, R.

    1998-05-01

    BVRI Observations of the star BD+05 706, carried out between January, 1997, and April 1998 using the 0.4m reflector and Photometrics CCD camera at the Gettysburg College Observatory, show that the star is an eclipsing binary system with a light curve characteristic of a class of semi-detached binaries known as the "cool Algols". These results are in good agreement with the previous report of BD+05 706 as a cool Algol by Torres, Neuhauser, and Wichmann,(Astron. J., 115, May 1998) who based their classification on the strong X-ray emission detected by Rosat and on a series of spectroscopic observations of the radial velocities of both components of the system obtained at the Oak Ridge Observatory, the Fred L. Whipple Observatory, and the Multiple Mirror Telescope. Only 10 other examples of cool Algols are known, and the current photometric light curve, together with the radial velocity curves obtained previously, allows us to derive a complete solution for the physical parameters of each component, providing important constraints on models for these interesting systems.

  8. Spectroscopic and photometric observations confirm XSS J12270-4859 in a low state

    NASA Astrophysics Data System (ADS)

    Casares Velazquez, J.; de Martino, D.; Mason, E.; D'Avanzo, P.; Campana, S.; Fugazza, D.; Covino, S.; Belloni, T.; Munoz-Darias, T.; Cornelisse, R.; Nicastro, L.

    2014-01-01

    We have observed the low-mass X-ray binary and gamma-ray source XSS J12270-4859/1FGL 1227.9-4852/2FGL 1227.7-4853 (de Martino et al. 2010, A&A 515, A25) on 2013 Dec 14.31, 15.32, 17.30 and 18.26 using the ESO NTT telescope. We employed EFOSC2 and Gr.#19 covering the range 4435-5109 Ang at 2.3 Ang resolution. Three 900s spectra and four 1200s spectra were obtained over the 4 nights. The spectra show metallic absorptions typical of mid/late G stars with no evidence for emission lines in any of them.

  9. Extreme-Ultraviolet Spectroscopic Observation of Direct Coronal Heating During a C-Class Solar Flare

    NASA Technical Reports Server (NTRS)

    Brosius, Jeffrey W.

    2012-01-01

    With the Coronal Diagnostic Spectrometer operating in rapid cadence (9.8 s) stare mode during a C6.6 flare on the solar disk, we observed a sudden brightening of Fe xix line emission (formed at temperature T ˜ 8 MK) above the pre-flare noise without a corresponding brightening of emission from ions formed at lower temperatures, including He i (0.01 MK), Ov (0.25 MK), and Si xii (2 MK). The sudden brightening persisted as a plateau of Fe xix intensity that endured more than 11 minutes. The Fe xix emission at the rise and during the life of the plateau showed no evidence of significant bulk velocity flows, and hence cannot be attributed to chromospheric evaporation. However, the line width showed a significant broadening at the rise of the plateau, corresponding to nonthermal velocities of at least 89 km s-1 due to reconnection outflows or turbulence. During the plateau He i, Ov, and Si xii brightened at successively later times starting about 3.5 minutes after Fe xix, which suggests that these brightenings were produced by thermal conduction from the plasma that produced the Fe xix line emission; however, we cannot rule out the possibility that they were produced by a weak beam of nonthermal particles. We interpret an observed shortening of the Ov wavelength for about 1.5 minutes toward the middle of the plateau to indicate new upward motions driven by the flare, as occurs during gentle chromospheric evaporation; relative to a quiescent interval shortly before the flare, the Ov upward velocity was around -10 km s-1.

  10. Direct spectroscopic observation of multiple-charged-ion acceleration by an intense femtosecond-pulse laser.

    PubMed

    Zhidkov, A G; Sasaki, A; Tajima, T; Auguste, T; D'Olivera, P; Hulin, S; Monot, P; Faenov, A Y; Pikuz, T A; Skobelev, I Y

    1999-09-01

    We have observed evidence of the emission of energetic He-and H-like ions of fluorine more than 1 MeV produced via the optical field ionization (OFI) from a solid target irradiated by an intense I=(2-4)x10(18) W/cm(2) (60 fs, lambda=800 nm), obliquely incident p-polarized pulse laser. The measured blue wing of He(alpha), He(beta), and Ly(alpha) lines of fluorine shows a feature of the Doppler-shifted spectrum due to the self-similar ion expansion dominated by superthermal electrons with the temperature T(h) approximately 100 keV. Using a collisional particle-in-cell simulation, which incorporates the nonlocal-thermodynamic-equilibrium ionization including OFI, we have obtained the plasma temperature, line shape, and maximal energy of accelerated ions, which agree well with those determined from the experimental spectra. The red wing of ion spectra gives the temperature of bulk plasma electrons.

  11. Direct spectroscopic observation of ion deceleration accompanying laser plasma-wall interaction

    NASA Astrophysics Data System (ADS)

    Renner, O.; Krouský, E.; Liska, R.; Šmíd, M.; Larroche, O.; Dalimier, E.; Rosmej, F. B.

    2010-08-01

    Interactions of plasma jets with solid surfaces are extensively studied in context with development of future fusion devices. In experiments carried out on the iodine laser system PALS, the energetic ions were produced at double-foil Al/Mg targets irradiated by one or two counter-propagating laser beams. The plasma jets from the rear surface of the laser-exploded Al foil streamed towards the Mg target representing the wall preheated by the action of the high-energy photons, particle and/or laser beams. Instead of being trapped by the cold secondary-target material, the forward-accelerated Al ions collided with the counter-propagating matter ejected from the wall. The environmental conditions in near-wall plasmas were analyzed with the high-resolution x-ray spectroscopy and temporally-resolved x-ray imaging. The deceleration of the incident Al ions in the near-wall region was directly observed and quantitatively characterized via Doppler shifts of the J-satellite from the Al Lya spectral group. The interaction scenario was modelled using the 2D arbitrary Lagrangian Eulerian hydrocode PALE and the multifluid code MULTIF.

  12. X-Ray Spectroscopic Observations with ASCA and BeppoSAX

    NASA Astrophysics Data System (ADS)

    Kaastra, J. S.

    Introduction X-ray spectroscopy The ASCA and BeppoSAX missions The most prominent spectral features observable with ASCA and - BeppoSAX A Few Notes on Spectral Data Fitting Introduction Data binning Model binning Calibration uncertainties Spectral deconvolution Statistics Low count rates Data presentation Plasma models Stellar Coronae Introduction Differential emission measure distribution techniques Temperature structure Abundances Flares Stellar evolution Hot Stars Introduction Normal O and B stars Luminous blue variables Wolf-Rayet stars Protostars and T Tauri Stars Introduction X-ray emission from protostars X-ray emission from T Tauri stars Cataclysmic Variables Introduction Non-magnetic cataclysmic variables Intermediate polars Polars High-Mass X-Ray Binaries Introduction Vela X-1 Cyg X-3 Cen X-3 SS 433 Other cases Low-Mass X-Ray Binaries Introduction 4U 1626-67 Cir X-1 Supernova Remnants Introduction Oxygen-ricg remnats: Cas A Young type Ia remnants Old shell-like remnants Synchrotron X-ray emission from SNRs Crab-like remnants Center-filled thermal remnants Jets interacting with SNRs Isolated pulsars The Magellanic Cloud SNRs Supernova explosions in distant galaxies Extended X-Ray Emission from Normal Galaxies The galactic ridge The galactic center X-ray emission from other normal galaxies Seyfert 1 Galaxies The iron line Warm absorbers The power law component Soft components Low-luminosity AGN Broad-line radio galaxies Seyfert 2 Galaxies Introduction NGC 1068 NGC 6552 NGC 4945 NGC 1808 Other cases Intermediate cases: narrow-line emission galaxies and others Quasars Radio-quiet quasars Radio-loud quasars Type 2 quasars BL Lac objects Clusters of Galaxies Temperature distribtuion of the hot medium The cooling flow and the central temperature distribtuion Mass distribution Groups of galaxies Cluster mergers and dynamical evolution Optical-depth effects The quest for the Hubble constant Abundances in nearby clusters Abundances in distant clusters Abundances

  13. Spectroscopic properties of explosive volcanism within the Caloris basin with MESSENGER observations

    NASA Astrophysics Data System (ADS)

    Besse, S.; Doressoundiram, A.; Benkhoff, J.

    2015-12-01

    Volcanism on Mercury has been indisputably identified at various locations on the surface, by means of both effusive and explosive volcanism. Its characterization is crucial to understand the evolution of the planet, in particular the thermal evolution of the mantle, and the volatile content of the planet. This analysis presents a detailed view of the pyroclastic deposits of the Caloris basin. Observations from the Mercury Atmospheric and Surface Composition Spectrometer (MASCS) are used to understand the spectral characteristics of the pyroclastic deposits, both in the visible and near-infrared. Additional calibration steps are proposed to reconcile the difference of absolute reflectance between the visible (VIS) and near-infrared (NIR) detectors. These calibration steps allow the use of the full spectral range of the MASCS instrument. Pyroclastic deposits exhibit a redder spectral slope in the VIS and NIR. This spectral slope diminishes toward the edge of the deposits to match that of Mercury's average surface. Spectral properties in the ultraviolet (UV) also change as a function of distance to the vent. Only the UV properties unambiguously separate the pyroclastic deposits from Mercury's average spectra. The spectral variations are consistent with a lower iron content of the pyroclastic deposits with respect to the average surface of Mercury, similar to what has been proposed for pyrolcastic deposits on the lunar surface. Nonetheless, given the limited illumination conditions diversity of the MASCS instrument, other causes such as grain size, space weathering, and bulk composition could also be accounted for the spectral variations. Variability of the pyroclastic deposits' properties within the entire basin are potentially identified between the three main clusters, and could be related to space weathering of deposits of different ages.

  14. A Bayesian Estimation for Spica's Apsidal Period from 111 years of Spectroscopic Observations

    NASA Astrophysics Data System (ADS)

    Aufdenberg, Jason P.; Robinette, Timothy M.

    2015-01-01

    Toward the goal of constraining the short period (P = 4.01 d) massive binary star Spica's apsidal constant, which in turn constrains the internal structure of the primary star (B1.5 IV), we have modified the Bayesian Markov Chain Monte Carlo code EXOFAST (Eastman et al. 2013) to fit six radial velocity (RV) data sets obtained between 1889 to 2000. The code was modified to take radial velocity input from two stars rather than a single exoplanet host star. In addition the apsidal period (U) and the RV amplitude of the secondary star (K2) have been added as fit parameters, and the longitude of periastron is now a function of time. Measurements from Vogel (1889), Baker (1910), Struve & Ebigghausen (1934), Struve et al. (1958), Shobbrook et al. (1972) and Riddle (2000) provide 338 and 239 RV measurements for the primary and secondary stars respectively.Preliminary results yield: (1) a median apsidal period (U) of 118.9±1.3 years with 68% confidence consistent with the value of Herbison-Evans et al. (1971), 124±11 years. The ratio of the orbital period to the apsidal period (P/U), one of three parameters needed for observationally determined apsidal-motion constant k2obs (Claret & Willems 2002), is now tentatively constrained to 1%, P/U = 9.24±0.01x10-5. (2) The eccentricity is constrained in our solution with an uncertainty of 9%, down from an uncertainly of 20% found by Riddle (2000). (3) The uncertainty in k2obs is dominated by the uncertainty of the ratio of the primary star radius, R1,to the semi-major axis, a, since k2obs is proportional to (R1/a)5. The semi-major axis can be found from a●sini which is constrained with an uncertainty of 3%, similar to previous work. The influence of the prior values on the posterior distributions will be described. The next step is to constrain the inclination from the light curve and long-baseline near-IR interferometry.

  15. Herschel spectroscopic observations of the compact obscured nucleus in Zw 049.057

    NASA Astrophysics Data System (ADS)

    Falstad, N.; González-Alfonso, E.; Aalto, S.; van der Werf, P. P.; Fischer, J.; Veilleux, S.; Meléndez, M.; Farrah, D.; Smith, H. A.

    2015-08-01

    Context. The luminous infrared galaxy Zw 049.057 contains a compact obscured nucleus where a considerable amount of the galaxy's luminosity is generated. This nucleus contains a dusty environment that is rich in molecular gas. One approach to probing this kind of environment and to revealing what is hidden behind the dust is to study the rotational lines of molecules that couple well with the infrared radiation emitted by the dust. Aims: We probe the physical conditions in the core of Zw 049.057 and establish the nature of its nuclear power source (starburst or active galactic nucleus). Methods: We observed Zw 049.057 with the Photodetector Array Camera and Spectrometer (PACS) and the Spectral and Photometric Imaging Receiver (SPIRE) onboard the Herschel Space Observatory in rotational lines of H2O, H218O, OH, 18OH, and [O I]. We modeled the unresolved core of the galaxy using a spherically symmetric radiative transfer code. To account for the different excitation requirements of the various molecular transitions, we use multiple components and different physical conditions. Results: We present the full high-resolution SPIRE FTS spectrum of Zw 049.057, along with relevant spectral scans in the PACS range. We find that a minimum of two different components (nuclear and extended) are required in order to account for the rich molecular line spectrum of Zw 049.057. The nuclear component has a radius of 10-30 pc, a very high infrared surface brightness (~1014L⊙kpc-2), warm dust (Td > 100 K), and a very large H2 column density (NH2 = 1024-1025 cm-2). The modeling also indicates high nuclear H2O (~5 × 10-6) and OH (~4 × 10-6) abundances relative to H2 as well as a low 16O/18O-ratio of 50-100. We also find a prominent infall signature in the [O I] line. We tentatively detect a 500 km s-1 outflow in the H2O 313 → 202 line. Conclusions: The high surface brightness of the core indicates the presence of either a buried active galactic nucleus or a very dense nuclear

  16. Nitrogen Isotopic Ratio of Cometary Ammonia from High-resolution Optical Spectroscopic Observations of C/2014 Q2 (Lovejoy)

    NASA Astrophysics Data System (ADS)

    Shinnaka, Yoshiharu; Kawakita, Hideyo

    2016-11-01

    The icy materials present in comets provide clues to the origin and evolution of our solar system and planetary systems. High-resolution optical spectroscopic observations of comet C/2014 Q2 (Lovejoy) were performed on 2015 January 11 (at 1.321 au pre-perihelion) with the High Dispersion Spectrograph mounted on the Subaru Telescope on Maunakea, Hawaii. We derive the 14N/15N ratio of NH2 (126 ± 25), as well as the ortho-to-para abundance ratios (OPRs) of the H2O+ ion (2.77 ± 0.24) and NH2 (3.38 ± 0.07), which correspond to nuclear spin temperatures of >24 K (3σ lower limit) and 27 ± 2 K, respectively. We also derive the intensity ratio of the green-to-red doublet of forbidden oxygen lines (0.107 ± 0.007). The ammonia in the comet must have formed under low-temperature conditions at ∼10 K or less to reproduce the observed 14N/15N ratio in this molecule if it is assumed that the 15N-fractionation of ammonia occurred via ion–molecule chemical reactions. However, this temperature is inconsistent with the nuclear spin temperatures of water and ammonia estimated from the OPRs. The interpretation of the nuclear spin temperature as the temperature at molecular formation may therefore be incorrect. An isotope-selective photodissociation of molecular nitrogen by protosolar ultraviolet radiation might play an important role in the 15N-fractionation observed in cometary volatiles.

  17. Spectroscopic observation of Lyα emitters at z ∼ 7.7 and implications on re-ionization

    SciTech Connect

    Faisst, A. L.; Carollo, C. M.; Capak, P.; Scarlata, C.; Scoville, N.

    2014-06-10

    We present spectroscopic follow-up observations on two bright Lyα emitter (LAE) candidates originally found by Krug et al. at a redshift of z ∼ 7.7 using the Multi-Object Spectrometer for Infra-Red Exploration at Keck. We rule out any line emission at the >5σ level for both objects, putting on solid ground a previous null result for one of the objects. The limits inferred from the non-detections rule out the previous claim of no or even reversed evolution between 5.7 < z < 7.7 in the Lyα luminosity function (LF) and suggest a drop in the Lyα LF consistent with that seen in Lyman break galaxy (LBG) samples. We model the redshift evolution of the LAE LF using the LBG UV-continuum LF and the observed rest-frame equivalent width distribution. From the comparison of our empirical model with the observed LAE distribution, we estimate lower limits of the neutral hydrogen fraction to be 50%-70% at z ∼ 7.7. Together with this, we find a strong evolution in the Lyα optical depth characterized by (1 + z){sup 2.2} {sup ±} {sup 0.5} beyond z = 6, indicative of a strong evolution of the intergalactic medium. Finally, we extrapolate the LAE LF to z ∼ 9 using our model and show that it is unlikely that large area surveys, like UltraVISTA or Euclid, pick up LAEs at this redshift assuming the current depths and area.

  18. Suzaku X-Ray and Optical Spectroscopic Observations of SS 433 in the 2006 April Multiwavelength Campaign

    NASA Astrophysics Data System (ADS)

    Kubota, Kaori; Ueda, Yoshihiro; Kawai, Nobuyuki; Kotani, Taro; Namiki, Masaaki; Kinugasa, Kenzo; Ozaki, Shinobu; Iijima, Takashi; Fabrika, Sergei; Yuasa, Takayuki; Yamada, Shin'ya; Makishima, Kazuo

    2010-04-01

    We report on results of the 2006 April multiwavelength campaign of SS 433, focusing on X-ray data observed with Suzaku at two orbital phases (in- and out-of-eclipse phases) and on simultaneous optical spectroscopic observations. Analyzing the FeXXV Kα lines originating from the jets, we detected a rapid variability of the Doppler shifts, dz/dt ≈ 0.019/0.33d-1, which is larger than those expected from the precession and/or nodding motion. This phenomenon probably corresponds to ``jitter'' motions observed for the first time in X-rays, for which significant variabilities in both the jet angle and the intrinsic speed are required. From time lags between optical Doppler curves and X-ray ones, we estimated a distance between the optical jets and the base to be ˜(3--4) × 1014cm. Based on the radiatively cooling jet model, we determined that the innermost temperatures of the jets are T0 = 13±2 keV for the out-of-eclipse phase and 16±3keV for the in-eclipse (the average of the blue and red jets) from the line intensity ratio of FeXXV Kα and FeXXVI Kα. While the broad-band-continuum spectra over the 5-40keV band in eclipse is consistent with a multitemperature-bremsstrahlung emission expected from the jets and its reflection component from cold matter, the out-of-eclipse spectrum is harder than the jet emission with the base temperature determined above, implying the presence of an additional hard component.

  19. Detection of optical path in spectroscopic space-based observations of greenhouse gases: Application to GOSAT data processing

    NASA Astrophysics Data System (ADS)

    Oshchepkov, Sergey; Bril, Andrey; Maksyutov, Shamil; Yokota, Tatsuya

    2011-07-01

    We present a method to detect optical path modification due to atmospheric light scattering in space-based greenhouse gas spectroscopic sounding. This method, which was applied to the analysis of radiance spectra measured by the Greenhouse Gases Observing Satellite (GOSAT), is based on the path length probability density function (PPDF) and on retrieval of PPDF parameters from radiance spectra in the oxygen A-band of absorption at 0.76 μm. We show that these parameters can be effectively used to characterize the impact of atmospheric light scattering on carbon dioxide retrieval in the atmospheric carbon dioxide (CO2) absorption bands at 1.6 μm and 2.0 μm. The threshold for PPDF parameters is set so that the optical-path modification is negligible, and these settings are recommended as a basic guideline for selecting the clearest atmospheric scenarios. An example of data processing for six global GOSAT repeat cycles in April and July 2009 shows that PPDF-based selection efficiently removes CO2 retrieval biases associated with subvisible cirrus and sandstorm activities.

  20. The Role of Involvement and Use in Multisite Evaluations

    ERIC Educational Resources Information Center

    Lawrenz, Frances; King, Jean A.; Ooms, Ann

    2011-01-01

    A cross-case analysis of four National Science Foundation (NSF) case studies identified both unique details and common themes related to promoting the use and influence of multisite evaluations. The analysis provided evidence of diverse evaluation use by stakeholders and suggested that people taking part in the multisite evaluations perceived…

  1. Building a Community of Evaluation Practice within a Multisite Program

    ERIC Educational Resources Information Center

    Goodyear, Leslie K.

    2011-01-01

    New and novel uses of evaluation processes and findings are possible when a community of practice develops as evaluation stakeholders participate in multisite evaluations in multiple ways. Developing such communities takes advantage of what makes multisite evaluations special. This chapter uses the example of the Innovative Technology Experiences…

  2. A Mixed Methods Sampling Methodology for a Multisite Case Study

    ERIC Educational Resources Information Center

    Sharp, Julia L.; Mobley, Catherine; Hammond, Cathy; Withington, Cairen; Drew, Sam; Stringfield, Sam; Stipanovic, Natalie

    2012-01-01

    The flexibility of mixed methods research strategies makes such approaches especially suitable for multisite case studies. Yet the utilization of mixed methods to select sites for these studies is rarely reported. The authors describe their pragmatic mixed methods approach to select a sample for their multisite mixed methods case study of a…

  3. A multisite validity study of self-reported anesthesia outcomes.

    PubMed

    Walker, Peter; Pekmezaris, Renee; Lesser, Martin L; Nouryan, Christian N; Rosinia, Frank; Pratt, Kathy; LaVopa, Catherine

    2012-01-01

    The purpose of this study was to assess the validity of a multisite anesthesia voluntary adverse event reporting process. A data validation methodology was used through medical chart review on live records at 3 facilities (N = 600). The per-item aggregated error rate among all 42 data items was 0.3%: 0.1% for quality indicators, 1.3% for demographic/status variables, and 1.7% for administrative items. The per-patient error rate among all 42 data items was 6.3%: 3.0% for quality indicators, 1.7% for demographic/status variables, and 3.0% for administrative items. Trends such as better accuracy for more serious events continue, but observed error rates were lower than those found in previous surveys-an indication that, while further study is needed, nonpunitive voluntary reporting may reduce errors in anesthesia care. PMID:22326979

  4. Spectroscopically resolved far-IR observations of the massive star-forming region G5.89-0.39

    NASA Astrophysics Data System (ADS)

    Leurini, S.; Wyrowski, F.; Wiesemeyer, H.; Gusdorf, A.; Güsten, R.; Menten, K. M.; Gerin, M.; Levrier, F.; Hübers, H. W.; Jacobs, K.; Ricken, O.; Richter, H.

    2015-12-01

    Context. The fine-structure line of atomic oxygen at 63 μm ([OI]63μm) is an important diagnostic tool in different fields of astrophysics: it is for example predicted to be the main coolant in several environments of star-forming regions (SFRs). However, our knowledge of this line relies on observations with low spectral resolution, and the real contribution of each component (photon-dominated region, jet) in the complex environment of SFRs to its total flux is poorly understood. Aims: We investigate the contribution of jet and photon-dominated region emission, and of absorption to the [OI]63μm line towards the hot gas around the ultra-compact Hii region G5.89-0.39 and study the far-IR line luminosity of the source in different velocity regimes through spectroscopically resolved spectra of atomic oxygen, [CII], CO, OH, and H2O. Methods: We mapped G5.89-0.39 in [OI]63μm and in CO(16-15) with the GREAT receiver onboard SOFIA. We also observed the central position of the source in the ground-state OH 2Π3/2 J = 5/2 → J = 3/2 triplet and in the excited OH 2Π1/2 J = 3/2 → J = 1/2 triplets with SOFIA. These data were complemented with APEX CO(6-5) and CO(7-6) maps and with Herschel/HIFI maps and single-pointing observations in lines of [CII], H2O, and HF. Results: The [OI] spectra in G5.89-0.39 are severely contaminated by absorptions from the source envelope and from different clouds along the line of sight. Emission is detected only at high velocities, and it is clearly associated with the compact north-south outflows traced by extremely high-velocity emission in low-J CO lines. The mass-loss rate and the energetics of the jet system derived from the [OI]63μm line agree well with previous estimates from CO, thus suggesting that the molecular outflows in G5.89-0.39 are driven by the jet system seen in [OI]. The far-IR line luminosity of G5.89-0.39 is dominated by [OI] at high-velocities; the second coolant in this velocity regime is CO, while [CII], OH and H2O

  5. Far Ultraviolet Spectroscopic Explorer Observations of the Seyfert 1.5 Galaxy NGC 5548 in a Low State

    NASA Technical Reports Server (NTRS)

    Brotherton, M. S.; Green, R. F.; Kriss, G. A.; Oegerle, W.; Kaiser, M. E.; Zheng, W.; Hutchings, J. B.; Fisher, Richard R. (Technical Monitor)

    2001-01-01

    We present far-ultraviolet spectra of the Seyfert 1.5 galaxy NGC 5548 obtained in 2000 June with the Far Ultraviolet Spectroscopic Explorer (FUSE). Our data span the observed wavelength range 915-1185 A at a resolution of approximately 20 km s(exp -1). The spectrum shows a weak continuum and emission from O VI (lambda)(lambda)1032, 1038, C III (lambda)977, and He II (lambda)1085. The FUSE data were obtained when the AGN (Active Galactic Nuclei) was in a low state, which has revealed strong, narrow O VI emission lines. We also resolve intrinsic, associated absorption lines of O VI and the Lyman series. Several distinct kinematic components are present, spanning a velocity range of approximately 0 to -1300 km s(exp -1) relative to systemic, with kinematic structure similar to that seen in previous observations of longer wavelength ultraviolet (UV) lines. We explore the relationships between the far-UV (ultraviolet) absorbers and those seen previously in the UV and X-rays. We find that the high-velocity UV absorption component is consistent with being low-ionization, contrary to some previous claims, and is consistent with its non-detection in high-resolution X-ray spectra. The intermediate velocity absorbers, at -300 to -400 km s(exp -1), show H I and O VI column densities consistent with having contributions from both a high-ionization X-ray absorber and a low-ionization UV absorber. No single far-UV absorbing component can be solely identified with the X-ray absorber.

  6. Mixed mechanisms of multi-site phosphorylation.

    PubMed

    Suwanmajo, Thapanar; Krishnan, J

    2015-06-01

    Multi-site phosphorylation is ubiquitous in cell biology and has been widely studied experimentally and theoretically. The underlying chemical modification mechanisms are typically assumed to be distributive or processive. In this paper, we study the behaviour of mixed mechanisms that can arise either because phosphorylation and dephosphorylation involve different mechanisms or because phosphorylation and/or dephosphorylation can occur through a combination of mechanisms. We examine a hierarchy of models to assess chemical information processing through different mixed mechanisms, using simulations, bifurcation analysis and analytical work. We demonstrate how mixed mechanisms can show important and unintuitive differences from pure distributive and processive mechanisms, in some cases resulting in monostable behaviour with simple dose-response behaviour, while in other cases generating new behaviour-like oscillations. Our results also suggest patterns of information processing that are relevant as the number of modification sites increases. Overall, our work creates a framework to examine information processing arising from complexities of multi-site modification mechanisms and their impact on signal transduction. PMID:25972433

  7. Long-term dynamics of multisite phosphorylation

    PubMed Central

    Rubinstein, Boris Y.; Mattingly, Henry H.; Berezhkovskii, Alexander M.; Shvartsman, Stanislav Y.

    2016-01-01

    Multisite phosphorylation cycles are ubiquitous in cell regulation systems and are studied at multiple levels of complexity, from molecules to organisms, with the ultimate goal of establishing predictive understanding of the effects of genetic and pharmacological perturbations of protein phosphorylation in vivo. Achieving this goal is essentially impossible without mathematical models, which provide a systematic framework for exploring dynamic interactions of multiple network components. Most of the models studied to date do not discriminate between the distinct partially phosphorylated forms and focus on two limiting reaction regimes, distributive and processive, which differ in the number of enzyme–substrate binding events needed for complete phosphorylation or dephosphorylation. Here we use a minimal model of extracellular signal-related kinase regulation to explore the dynamics of a reaction network that includes all essential phosphorylation forms and arbitrary levels of reaction processivity. In addition to bistability, which has been studied extensively in distributive mechanisms, this network can generate periodic oscillations. Both bistability and oscillations can be realized at high levels of reaction processivity. Our work provides a general framework for systematic analysis of dynamics in multisite phosphorylation systems. PMID:27226482

  8. Long-term dynamics of multisite phosphorylation.

    PubMed

    Rubinstein, Boris Y; Mattingly, Henry H; Berezhkovskii, Alexander M; Shvartsman, Stanislav Y

    2016-07-15

    Multisite phosphorylation cycles are ubiquitous in cell regulation systems and are studied at multiple levels of complexity, from molecules to organisms, with the ultimate goal of establishing predictive understanding of the effects of genetic and pharmacological perturbations of protein phosphorylation in vivo. Achieving this goal is essentially impossible without mathematical models, which provide a systematic framework for exploring dynamic interactions of multiple network components. Most of the models studied to date do not discriminate between the distinct partially phosphorylated forms and focus on two limiting reaction regimes, distributive and processive, which differ in the number of enzyme-substrate binding events needed for complete phosphorylation or dephosphorylation. Here we use a minimal model of extracellular signal-related kinase regulation to explore the dynamics of a reaction network that includes all essential phosphorylation forms and arbitrary levels of reaction processivity. In addition to bistability, which has been studied extensively in distributive mechanisms, this network can generate periodic oscillations. Both bistability and oscillations can be realized at high levels of reaction processivity. Our work provides a general framework for systematic analysis of dynamics in multisite phosphorylation systems. PMID:27226482

  9. OBSERVING THE FINE STRUCTURE OF LOOPS THROUGH HIGH-RESOLUTION SPECTROSCOPIC OBSERVATIONS OF CORONAL RAIN WITH THE CRISP INSTRUMENT AT THE SWEDISH SOLAR TELESCOPE

    SciTech Connect

    Antolin, P.; Rouppe van der Voort, L. E-mail: v.d.v.l.rouppe@astro.uio.no

    2012-02-01

    Observed in cool chromospheric lines, such as H{alpha} or Ca II H, coronal rain corresponds to cool and dense plasma falling from coronal heights. Considered as a peculiar sporadic phenomenon of active regions, it has not received much attention since its discovery more than 40 years ago. Yet, it has been shown recently that a close relationship exists between this phenomenon and the coronal heating mechanism. Indeed, numerical simulations have shown that this phenomenon is most likely due to a loss of thermal equilibrium ensuing from a heating mechanism acting mostly toward the footpoints of loops. We present here one of the first high-resolution spectroscopic observations of coronal rain, performed with the CRisp Imaging Spectro Polarimeter (CRISP) instrument at the Swedish Solar Telescope. This work constitutes the first attempt to assess the importance of coronal rain in the understanding of the coronal magnetic field in active regions. With the present resolution, coronal rain is observed to literally invade the entire field of view. A large statistical set is obtained in which dynamics (total velocities and accelerations), shapes (lengths and widths), trajectories (angles of fall of the blobs), and thermodynamic properties (temperatures) of the condensations are derived. Specifically, we find that coronal rain is composed of small and dense chromospheric cores with average widths and lengths of {approx}310 km and {approx}710 km, respectively, average temperatures below 7000 K, displaying a broad distribution of falling speeds with an average of {approx}70 km s{sup -1}, and accelerations largely below the effective gravity along loops. Through estimates of the ion-neutral coupling in the blobs we show that coronal rain acts as a tracer of the coronal magnetic field, thus supporting the multi-strand loop scenario, and acts as a probe of the local thermodynamic conditions in loops. We further elucidate its potential in coronal heating. We find that the cooling

  10. Follow-up spectroscopic observations of HD 107148 B: A new white dwarf companion of an exoplanet host star

    NASA Astrophysics Data System (ADS)

    Mugrauer, M.; Dinçel, B.

    2016-07-01

    We report on our follow-up spectroscopy of HD 1071478 B, a recently detected faint co-moving companion of the exoplanet host star HD 107148 A. The companion is separated from its primary star by about 35 arcsec (or 1790 AU of projected separation) and its optical and near infrared photometry is consistent with a white dwarf, located at the distance of HD 107148 A. In order to confirm the white dwarf nature of the co-moving companion, we obtained follow-up spectroscopic observations of HD 107148 B with CAFOS at the CAHA 2.2 m telescope. According to our CAFOS spectroscopy HD 107148 B is a DA white dwarf with an effective temperature in the range between 5900 and 6400 K. The properties of HD 107148 B can further be constrained with the derived effective temperature and the known visual and infrared photometry of the companion, using evolutionary models of DA white dwarfs. We obtain for HD 107148 B a mass of 0.56±0.05 M_⊙, a luminosity of (2.0±0.2)×10-4 L_⊙, log g [cm s-2])=7.95±0.09, and a cooling age of 2100±270 Myr. With its white dwarf companion the exoplanet host star HD 107148 A forms an evolved stellar system, which hosts at least one exoplanet. So far, only few of these evolved systems are known, which represent only about 5 % of all known exoplanet host multiple stellar systems. HD 107148 B is the second confirmed white dwarf companion of an exoplanet host star with a projected separation to its primary star of more than 1000 AU. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).

  11. Follow-up spectroscopic observations of HD 107148 B: A new white dwarf companion of an exoplanet host star

    NASA Astrophysics Data System (ADS)

    Mugrauer, M.; Dinçel, B.

    2016-07-01

    We report on our follow-up spectroscopy of HD 1071478 B, a recently detected faint co-moving companion of the exoplanet host star HD 107148 A. The companion is separated from its primary star by about 35 arcsec (or 1790 AU of projected separation) and its optical and near infrared photometry is consistent with a white dwarf, located at the distance of HD 107148 A. In order to confirm the white dwarf nature of the co-moving companion, we obtained follow-up spectroscopic observations of HD 107148 B with CAFOS at the CAHA 2.2 m telescope. According to our CAFOS spectroscopy HD 107148 B is a DA white dwarf with an effective temperature in the range between 5900 and 6400 K. The properties of HD 107148 B can further be constrained with the derived effective temperature and the known visual and infrared photometry of the companion, using evolutionary models of DA white dwarfs. We obtain for HD 107148 B a mass of 0.56±0.05 M_ȯ, a luminosity of (2.0±0.2)×10-4 L_ȯ, log g [cm s-2])=7.95±0.09, and a cooling age of 2100±270 Myr. With its white dwarf companion the exoplanet host star HD 107148 A forms an evolved stellar system, which hosts at least one exoplanet. So far, only few of these evolved systems are known, which represent only about 5 % of all known exoplanet host multiple stellar systems. HD 107148 B is the second confirmed white dwarf companion of an exoplanet host star with a projected separation to its primary star of more than 1000 AU. Based on observations collected at the Centro Astronómico Hispano Alemán (CAHA) at Calar Alto, operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC).

  12. Evaluation of spectroscopic databases through radiative transfer simulations compared to observations. Application to the validation of GEISA 2015 with IASI and TCCON

    NASA Astrophysics Data System (ADS)

    Armante, Raymond; Scott, Noelle; Crevoisier, Cyril; Capelle, Virginie; Crepeau, Laurent; Jacquinet, Nicole; Chédin, Alain

    2016-09-01

    The quality of spectroscopic parameters that serve as input to forward radiative transfer models are essential to fully exploit remote sensing of Earth atmosphere. However, the process of updating spectroscopic databases in order to provide the users with a database that insures an optimal characterization of spectral properties of molecular absorption for radiative transfer modeling is challenging. The evaluation of the databases content and the underlying choices made by the managing team is thus a crucial step. Here, we introduce an original and powerful approach for evaluating spectroscopic parameters: the Spectroscopic Parameters And Radiative Transfer Evaluation (SPARTE) chain. The SPARTE chain relies on the comparison between forward radiative transfer simulations made by the 4A radiative transfer model and observations of spectra made from various observations collocated over several thousands of well-characterized atmospheric situations. Averaging the resulting 'calculated-observed spectral' residuals minimizes the random errors coming from both the radiometric noise of the instruments and the imperfect description of the atmospheric state. The SPARTE chain can be used to evaluate any spectroscopic databases, from the visible to the microwave, using any type of remote sensing observations (ground-based, airborne or space-borne). We show that the comparison of the shape of the residuals enables: (i) identifying incorrect line parameters (line position, intensity, width, pressure shift, etc.), even for molecules for which interferences between the lines have to be taken into account; (ii) proposing revised values, in cooperation with contributing teams; and (iii) validating the final updated parameters. In particular, we show that the simultaneous availability of two databases such as GEISA and HITRAN helps identifying remaining issues in each database. The SPARTE chain has been here applied to the validation of the update of GEISA-2015 in 2 spectral regions

  13. Latent Variable Regression 4-Level Hierarchical Model Using Multisite Multiple-Cohorts Longitudinal Data. CRESST Report 801

    ERIC Educational Resources Information Center

    Choi, Kilchan

    2011-01-01

    This report explores a new latent variable regression 4-level hierarchical model for monitoring school performance over time using multisite multiple-cohorts longitudinal data. This kind of data set has a 4-level hierarchical structure: time-series observation nested within students who are nested within different cohorts of students. These…

  14. Multisite Interactions in Lattice-Gas Models

    NASA Astrophysics Data System (ADS)

    Einstein, T. L.; Sathiyanarayanan, R.

    For detailed applications of lattice-gas models to surface systems, multisite interactions often play at least as significant a role as interactions between pairs of adatoms that are separated by a few lattice spacings. We recall that trio (3-adatom, non-pairwise) interactions do not inevitably create phase boundary asymmetries about half coverage. We discuss a sophisticated application to an experimental system and describe refinements in extracting lattice-gas energies from calculations of total energies of several different ordered overlayers. We describe how lateral relaxations complicate matters when there is direct interaction between the adatoms, an issue that is important when examining the angular dependence of step line tensions. We discuss the connector model as an alternative viewpoint and close with a brief account of recent work on organic molecule overlayers.

  15. Multisite EPR Oximetry from Multiple Quadrature Harmonics

    PubMed Central

    Ahmad, R.; Som, S.; Johnson, D.H.; Zweier, J.L.; Kuppusamy, P.; Potter, L.C.

    2011-01-01

    Multisite continuous wave (CW) electron paramagnetic resonance (EPR) oximetry using multiple quadrature field modulation harmonics is presented. First, a recently developed digital receiver is used to extract multiple harmonics of field modulated projection data. Second, a forward model is presented that relates the projection data to unknown parameters, including linewidth at each site. Third, a maximum likelihood estimator of unknown parameters is reported using an iterative algorithm capable of jointly processing multiple quadrature harmonics. The data modeling and processing are applicable for parametric lineshapes under nonsaturating conditions. Joint processing of multiple harmonics leads to 2-3 fold acceleration of EPR data acquisition. For demonstration in two spatial dimensions, both simulations and phantom studies on an L-band system are reported. PMID:22154283

  16. Unlimited multistability in multisite phosphorylation systems.

    PubMed

    Thomson, Matthew; Gunawardena, Jeremy

    2009-07-01

    Reversible phosphorylation on serine, threonine and tyrosine is the most widely studied posttranslational modification of proteins. The number of phosphorylated sites on a protein (n) shows a significant increase from prokaryotes, with n /= 150 sites. Multisite phosphorylation has many roles and site conservation indicates that increasing numbers of sites cannot be due merely to promiscuous phosphorylation. A substrate with n sites has an exponential number (2(n)) of phospho-forms and individual phospho-forms may have distinct biological effects. The distribution of these phospho-forms and how this distribution is regulated have remained unknown. Here we show that, when kinase and phosphatase act in opposition on a multisite substrate, the system can exhibit distinct stable phospho-form distributions at steady state and that the maximum number of such distributions increases with n. Whereas some stable distributions are focused on a single phospho-form, others are more diffuse, giving the phospho-proteome the potential to behave as a fluid regulatory network able to encode information and flexibly respond to varying demands. Such plasticity may underlie complex information processing in eukaryotic cells and suggests a functional advantage in having many sites. Our results follow from the unusual geometry of the steady-state phospho-form concentrations, which we show to constitute a rational algebraic curve, irrespective of n. We thereby reduce the complexity of calculating steady states from simulating 3 x 2(n) differential equations to solving two algebraic equations, while treating parameters symbolically. We anticipate that these methods can be extended to systems with multiple substrates and multiple enzymes catalysing different modifications, as found in posttranslational modification 'codes' such as the histone code. Whereas simulations struggle with exponentially increasing molecular complexity

  17. Spectroscopic mode identification of main-sequence non-radially pulsating stars

    NASA Astrophysics Data System (ADS)

    Maisonneuve, F.; Pollard, K. R.; Cottrell, P. L.; Kilmartin, P. M.; Wright, D. J.; De Cat, P.

    2010-07-01

    We are undertaking an extensive observational campaign of a number of non-radially pulsating stars using the high-resolution HERCULES spectrograph on the 1.0-m telescope at the Mt John University Observatory. This is part of a large world-wide multi-site campaign to improve mode-identification techniques in non-radially pulsating stars, particularly for g-mode pulsators. This paper outlines our campaign and presents preliminary results for one γ Doradus star, HD 40745, and one β Cephei star, HD 61068. We have used a representative cross-correlation line-profile technique presented by Wright in 2008 to extract line profiles and these have then been analyzed using the FAMIAS package due to Zima published in 2006 to derive a spectroscopic mode identification.

  18. A digital toolkit to implement and manage a multisite study.

    PubMed

    Lasater, Kathie; Johnson, Elizabeth; Hodson-Carlton, Kay; Siktberg, Linda; Sideras, Stephanie

    2012-03-01

    Calls for multisite studies are increasing in nursing education. However, the challenge of implementing consistent protocols and maintaining rigorous standards across sites can be daunting. One purpose of a recent multisite, collaborative, simulation study was to evaluate a digital toolkit's effectiveness for managing a multisite study. We describe the digital toolkit composed of Web-based technologies used to manage a study involving five sites including one United Kingdom site. The digital toolkit included a wiki, a project Web site to coordinate the protocols and study materials, software to organize study materials, and a secure location for sharing data. Most of these are familiar tools; however, combined as a toolkit, they became a useful management system. Web-based communication strategies and coordinated technical support served as key adjuncts to foster collaboration. This article also offers practical implications and recommendations for using a digital toolkit in other multisite studies.

  19. Optical low-dispersion spectroscopic observations of Comet 103P/Hartley 2 at Koyama Astronomical Observatory during the EPOXI flyby

    NASA Astrophysics Data System (ADS)

    Shinnaka, Yoshiharu; Kawakita, Hideyo; Kobayashi, Hitomi; Naka, Chiharu; Arai, Akira; Arasaki, Takayuki; Kitao, Eiji; Taguchi, Gaku; Ikeda, Yuji

    2013-02-01

    We performed low-dispersion spectroscopic observations of Comet 103P/Hartley 2 in optical wavelengths using the LOSA/F2 mounted on the 1.3 m-Araki telescope at Koyama Astronomical Observatory on UT 2010 November 4 during the close approach of the Deep Impact spacecraft to the nucleus of Comet 103P/Hartley 2 in the EPOXI mission flyby. Our observations have revealed the chemistry of the coma at optical wavelengths; including CN, C3, C2 and NH2 along with H2O from [OI] emission at 6300 Å. Resultant mixing ratios of these radicals put the comet into the normal group in chemical composition. The mixing ratios with respect to H2O obtained in our observations are basically consistent with the previous optical spectro-photometric observations of Comet 103P/Hartley 2 in 1991 by A'Hearn et al. (A'Hearn, M.F., Millis, R.L., Schleicher, D.G., Osip, D.J., Birch, P.V. [1995]. Icarus 118, 223-270), the optical spectroscopic observations in 1998 by Fink (Fink, U. [2009]. Icarus 201, 311-334) and also consistent with the observations on UT 2010 October 27 and 29 by Lara et al. (Lara, L.M., Lin, Z.-Y., Meech, K. [2011]. Astron. Astrophys. 532, A87) (but only for the ratio relative to CN).

  20. Nonlinear instabilities of multi-site breathers in Klein-Gordon lattices

    SciTech Connect

    Cuevas-Maraver, Jesus; Kevrekidis, Panayotis G.; Pelinovsky, Dmitry E.

    2015-12-14

    Here, we explore the possibility of multi-site breather states in a nonlinear Klein–Gordon lattice to become nonlinearly unstable, even if they are found to be spectrally stable. The mechanism for this nonlinear instability is through the resonance with the wave continuum of a multiple of an internal mode eigenfrequency in the linearization of excited breather states. For the nonlinear instability, the internal mode must have its Krein signature opposite to that of the wave continuum. This mechanism is not only theoretically proposed, but also numerically corroborated through two concrete examples of the Klein–Gordon lattice with a soft (Morse) and a hard (Φ4) potential. Compared to the case of the nonlinear Schrödinger lattice, the Krein signature of the internal mode relative to that of the wave continuum may change depending on the period of the multi-site breather state. For the periods for which the Krein signatures of the internal mode and the wave continuum coincide, multi-site breather states are observed to be nonlinearly stable.

  1. Nonlinear instabilities of multi-site breathers in Klein-Gordon lattices

    DOE PAGES

    Cuevas-Maraver, Jesus; Kevrekidis, Panayotis G.; Pelinovsky, Dmitry E.

    2015-12-14

    Here, we explore the possibility of multi-site breather states in a nonlinear Klein–Gordon lattice to become nonlinearly unstable, even if they are found to be spectrally stable. The mechanism for this nonlinear instability is through the resonance with the wave continuum of a multiple of an internal mode eigenfrequency in the linearization of excited breather states. For the nonlinear instability, the internal mode must have its Krein signature opposite to that of the wave continuum. This mechanism is not only theoretically proposed, but also numerically corroborated through two concrete examples of the Klein–Gordon lattice with a soft (Morse) and amore » hard (Φ4) potential. Compared to the case of the nonlinear Schrödinger lattice, the Krein signature of the internal mode relative to that of the wave continuum may change depending on the period of the multi-site breather state. For the periods for which the Krein signatures of the internal mode and the wave continuum coincide, multi-site breather states are observed to be nonlinearly stable.« less

  2. A nonparametric kernel regression model for downscaling multisite daily precipitation in the Mahanadi basin

    NASA Astrophysics Data System (ADS)

    Kannan, S.; Ghosh, Subimal

    2013-03-01

    Hydrologic impacts of global climate change are usually assessed by downscaling large-scale climate variables, simulated by general circulation models (GCMs), to local-scale hydrometeorological variables. Conventional multisite statistical downscaling techniques often fail to capture spatial dependence of rainfall amounts as well as hydrometeorological extremes. To overcome these limitations, a downscaling algorithm is proposed, which first simulates the rainfall state of an entire study area/river basin, from large-scale climate variables, with classification and regression trees, and then projects multisite rainfall amounts using a nonparametric kernel regression estimator, conditioned on the estimated rainfall state. The concept of a common rainfall state for the entire study area, using it as an input for projections of rainfall amount, is found to be advantageous in capturing the cross correlation between rainfalls at different downscaling locations. Temporal variability and extremities of rainfall are captured in downscaling with multivariate kernel regression. The proposed model is applied for downscaling daily monsoon precipitation at eight locations in the Mahanadi River basin of eastern India. The model performance is compared, with a recently developed conditional random field based as well as with established multisite downscaling models, and is found to be superior. Analysis of future rainfall scenarios, projected with the developed downscaling model, reveals considerable changes in rainfall intensity and dry and wet spell lengths, among other things, at different locations. An increasing trend of rainfall is projected for the lower (southern) Mahanadi River basin, and a decreasing trend is observed in the upper (northern) Mahanadi River basin.

  3. Variations in the D/H Ratio of Extended Sight Lines from Far Ultraviolet Spectroscopic Explorer Observations

    NASA Astrophysics Data System (ADS)

    Oliveira, Cristina M.; Hébrard, Guillaume

    2006-12-01

    We use new FUSE data to determine the column densities of interstellar D I, N I, O I, Fe II, and H2 along the HD 41161 and HD 53975 sight lines. Together with N(H I) from the literature, we derive D/H, N/H, and O/H ratios. These sight lines have logN(H I)>21.00 and probe gas up to ~1300 pc, allowing us to determine the gas-phase D/H ratio in a hydrogen column density range, logN(H)>20.70, where the only five measurements available in the literature yield a weighted average of D/H=(0.86+/-0.08)×10-5. We find D/H=(2.14+0.51-0.43)×10-5 along the HD 41161 sight line. This ratio is ~3 σ higher than the weighted mean D/H ratio quoted above, while the D/H ratio for the HD 53975 line of sight, D/H=(1.02+0.23-0.20)×10-5, agrees within the 1 σ uncertainties. Our D/H measurement along the HD 41161 sight line presents the first evidence of variations of D/H at high N(H). Our result seems to indicate either that the long sight lines that, according to the deuterium depletion model, are dominated by cold undisturbed gas where deuterium would be depleted onto carbonaceous grains occur at higher N(H) than previously thought, or that the clumping of low D/H values in the literature for the long sight lines has another explanation. Both of the O/H ratios derived here, (9.12+2.15-1.83)×10-4 and (5.37+1.35-1.14)×10-4 (for HD 41161 and HD 53975, respectively), are higher than what has been found by other authors. Finally, we derive (N/H)×105=8.32+2.09-1.76 and 5.07+1.45-1.21, and (D/O)×102=2.29+0.40-0.35 and 1.91+0.51-0.43, for HD 41161 and HD 53975, respectively. In addition, the relatively high signal-to-noise ratio of the HD 41161 data allows us to place constraints on the f-values of some neutral chlorine transitions present in the FUSE bandpass for which only theoretical values are available. Based on observations made with the NASA-CNES-CSA Far Ultraviolet Spectroscopic Explorer. FUSE is operated for NASA by the Johns Hopkins University under NASA contract NAS5-32985.

  4. Multisite adsorption of cadmium on goethite

    SciTech Connect

    Venema, P.; Hiemstra, T.; Riemsdijk, W.H. van

    1996-11-10

    Recently a new general ion adsorption model has been developed for ion binding to mineral surfaces (Hiemstra and van Riemsdijk, 1996). The model uses the Pauling concept of charge distribution (CD) and is an extension of the multi-site complexation (MUSIC) approach. In the CD-MUSIC model the charge of an adsorbing ion that forms an inner sphere complex is distributed over its ligands, which are present in two different electrostatic planes. In this paper the authors have applied the CD-MUSIC model to the adsorption of metal cations, using an extended data set for cadmium adsorbing on goethite. The adsorption of cadmium and the cadmium-proton exchange ratio were measured as function of metal ion concentration, pH, and ionic strength. The data could be described well, taking into account the surface heterogeneity resulting from the presence of two different crystal planes (the dominant 110 face and the minor 021 face). The surface species used in the model are consistent with recent EXAFS data. In accordance with the EXAFS results, high-affinity complexes at the 021 face were used in the model.

  5. The Wasilewski sample of emission-line galaxies - Follow-up CCD imaging and spectroscopic and IRAS observations

    NASA Technical Reports Server (NTRS)

    Bothun, Gregory D.; Schmitz, Mark; Halpern, Jules P.; Lonsdale, Carol J.; Impey, Chris

    1989-01-01

    The results of an extensive imaging and spectroscopic follow-up of the objective prism-selected emission line galaxy (ELG) sample of Wasilewski (1982) are presented. Fluxes at 12, 25, 60, and 100 microns were also obtained from the coadded IRAS survey data. ELGs found by objective prism surveys are found to be generally small and underluminous galaxies which usually have higher than average optical surface brightness. The Seyfert detection rate in objective prism surveys is roughly 10 percent and the ratio of the space densities of Seyfert 2 to Seyfert 1 galaxies is significantly larger than unity. Most of the galaxies selected by objective prism surveys are star-forming, late-type spirals which often show disturbed morphology. About 25 percent of the galaxies detected by the surveys are faint, high-excitation metal-poor compact H II regions.

  6. Multi-site continuous spectroscopy. 2: Spectrophotometry and energy budget of exceptional white-light flares on HR 1099 from the MUSICOS 89 campaign

    NASA Astrophysics Data System (ADS)

    Foing, B. H.; Char, S.; Ayres, T.; Catala, C.; Neff, J. E.; Zhai, D. S.; Catalano, S.; Cutispoto, G.; Jankov, S.; Rodono, M.; Simon, T.; Akan, C.; Aslanov, A.; Avellar, P.; Baudrand, J.; Beust, H.; Cao, H.; Chatzichristou, H.; Cuby, J. G.; Czarny, J.; de La Reza, R.; Dreux, M.; Felenbok, P.; Ferlet, R.; Frasca, A.; Floquet, M.; Ghosh, K.; Guo, Z.; Guerin, J.; Hao, J. X.; Houdebine, E. R.; Huang, L.; Hubert, A. M.; Hubert, H.; Huovelin, J.; Hron, J.; Ibanoglu, C.; Jiang, S.; Keskin, V.; Lagrange-Henri, A. M.; Lecontel, J. M.; Li, Q.; Mavridis, L.; Nolthenius, R.; Petrov, P.; Savanov, I.; Scherbakov, A.; Tuominen, I.; Vidal-Madjar, A.; Zhang, R.; Zhang, X.

    1994-12-01

    We report results from the December 89 multi-site continuous observing campaign (MUSICOS (MUlti-SIte COntinuous Spectroscopic) 89) dedicated to the study of surface active structures and flares on the RS CVn-type system HR 1099 (= V711 Tau). This system has been observed by up to 17 telescopes around the globe during this campaign. We obtained complete phase coverage for Doppler imaging of photospheric spots. Quasi-simultaneously, we observed the modulation of Ca II K line profile due to chromospheric plage regions. At least two exceptional white-light flares on 14 Dec. 15:00 UT and 15 Dec. 1:00 UT (the largest such optical flare episode ever reported in a RS CVn system) were detected photometrically with typical rise and decay times of 60-90 min, and with remarkable spectral dynamic signatures in H-alpha with longer decay time scale. Equivalent colors, temperature excesses and projected flare areas (0.55 and 0.89 solar disc areas) were derived for the two optical flares. We estimate the energy budget for these two events, with respective peak intensities of radiative losses of 1.65 and 14 x 1033 erg/s and integrated losses over the white-light event duration of a few hours of 8 x 1036 and 1038 ergs (in the 3100-5900 A range), indicating a total energy balance several times these values. The emission was also measured in the H-alpha and H-Beta lines during these flares with a ratio of flare optical emission over Balmer emission 3-4 times larger compared to other flares on dwarfs. More than one day after the last white-light flare, part of the flare decay phase was also measured with IUE in UV lines of low and high excitation; the extrapolated transition region EUV losses are found similar to the derived Balmer line losses. Both flares were shown to occur near the limb. We derive their physical area, and estimate their densities, column mass, and penetration depth. From Balmer line broadening and flows, we derive a kinetic energy budget comparable to the radiative

  7. Real-Time Enrollment Dashboard For Multisite Clinical Trials

    PubMed Central

    Mattingly, William A; Kelley, Robert R; Wiemken, Timothy L; Chariker, Julia H; Peyrani, Paula; Guinn, Brian E; Binford, Laura E; Buckner, Kimberley; Ramirez, Julio

    2015-01-01

    Objective Achieving patient recruitment goals are critical for the successful completion of a clinical trial. We designed and developed a web-based dashboard for assisting in the management of clinical trial screening and enrollment. Materials and Methods We use the dashboard to assist in the management of two observational studies of community-acquired pneumonia. Clinical research associates and managers using the dashboard were surveyed to determine its effectiveness as compared with traditional direct communication. Results The dashboard has been in use since it was first introduced in May of 2014. Of the 23 staff responding to the survey, 77% felt that it was easier or much easier to use the dashboard for communication than to use direct communication. Conclusion We have designed and implemented a visualization dashboard for managing multi-site clinical trial enrollment in two community acquired pneumonia studies. Information dashboards are a useful tool for clinical trial management. They can be used as a standalone trial information tool or included into a larger management system. PMID:26878068

  8. Optical spectroscopic observations of blazars and γ-ray blazar candidates in the Sloan digital sky survey data release nine

    SciTech Connect

    Massaro, F.; Masetti, N.; D'Abrusco, R.; Paggi, A.; Funk, S.

    2014-10-01

    We present an analysis of the optical spectra available in the Sloan Digital Sky Survey data release nine (SDSS DR9) for the blazars listed in the ROMA-BZCAT and for the γ-ray blazar candidates selected according to their IR colors. First, we adopt a statistical approach based on Monte Carlo simulations to find the optical counterparts of the blazars listed in the ROMA-BZCAT catalog. Then, we crossmatched the SDSS spectroscopic catalog with our selected samples of blazars and γ-ray blazar candidates, searching for those with optical spectra available to classify our blazar-like sources and, whenever possible, to confirm their redshifts. Our main objectives are to determine the classification of uncertain blazars listed in the ROMA-BZCAT and to discover new gamma-ray blazars. For the ROMA-BZCAT sources, we investigated a sample of 84 blazars, confirming the classification for 20 of them and obtaining 18 new redshift estimates. For the γ-ray blazars, indicated as potential counterparts of unassociated Fermi sources or with uncertain nature, we established the blazar-like nature of 8 out of the 27 sources analyzed and confirmed 14 classifications.

  9. Development of a high dynamic range spectroscopic system for observation of neutral hydrogen atom density distribution in Large Helical Device core plasma

    SciTech Connect

    Fujii, K. Atsumi, S.; Watanabe, S.; Shikama, T.; Hasuo, M.; Goto, M.; Morita, S.

    2014-02-15

    We report development of a high dynamic range spectroscopic system comprising a spectrometer with 30% throughput and a camera with a low-noise fast-readout complementary metal-oxide semiconductor sensor. The system achieves a 10{sup 6} dynamic range (∼20 bit resolution) and an instrumental function approximated by a Voigt profile with Gauss and Lorentz widths of 31 and 0.31 pm, respectively, for 656 nm light. The application of the system for line profile observations of the Balmer-α emissions from high temperature plasmas generated in the Large Helical Device is also presented. In the observed line profiles, emissions are detected in far wings more than 1.0 nm away from the line center, equivalent to neutral hydrogen atom kinetic energies above 1 keV. We evaluate atom density distributions in the core plasma by analyzing the line profiles.

  10. A review of multisite pacing to achieve cardiac resynchronization therapy.

    PubMed

    Rinaldi, Christopher Aldo; Burri, Haran; Thibault, Bernard; Curnis, Antonio; Rao, Archana; Gras, Daniel; Sperzel, Johannes; Singh, Jagmeet P; Biffi, Mauro; Bordachar, Pierre; Leclercq, Christophe

    2015-01-01

    Non-response to cardiac resynchronization therapy remains a significant problem in up to 30% of patients. Multisite stimulation has emerged as a way of potentially overcoming non-response. This may be achieved by the use of multiple leads placed within the coronary sinus and its tributaries (dual-vein pacing) or more recently by the use of multipolar (quadripolar) left ventricular pacing leads which can deliver pacing stimuli at multiple sites within the same vein. This review covers the role of multisite pacing including the interaction with the underlying pathophysiology, the current and planned studies, and the potential pitfalls of this technology. PMID:25214507

  11. Time-Resolved Spectroscopic Observation of Deposition Processes of Ultrananocrystalline Diamond/Amorphous Carbon Composite Films by Using a Coaxial Arc Plasma Gun

    NASA Astrophysics Data System (ADS)

    Hanada, Kenji; Yoshitake, Tsuyoshi; Nishiyama, Takashi; Nagayama, Kunihito

    2010-08-01

    The deposition of ultrananocrystalline diamond (UNCD)/amorphous carbon composite films using a coaxial arc plasma gun in vacuum and, for comparison, in a 53.3 Pa hydrogen atmosphere was spectroscopically observed using a high-speed camera equipped with narrow-band-pass filters. UNCD crystallites with diameters of approximately 1.6 nm were formed even in vacuum. These extremely small crystallites imply that the formation is predominantly due to nucleation without the subsequent growth. Even in vacuum, emissions from C+ ions, C atoms, and C2 dimers lasted for approximately 100 µs, although the emission lifetimes of these species are generally 10 ns. We consider that the nucleation is due to the supersaturated environment containing excited carbon species with large number densities.

  12. Multi-Sited Ethnography and the Field of Educational Research

    ERIC Educational Resources Information Center

    Pierides, Dean

    2010-01-01

    This paper responds to the challenge of how educational research might be practised in a contemporary world that is no longer necessarily organised by nearness and unity. Focusing on ethnography, it argues for what a multi-sited imaginary contributes to research in the field of education. By giving prominence to the notion of multi-sited…

  13. A Multisite Cluster Randomized Field Trial of Open Court Reading

    ERIC Educational Resources Information Center

    Borman, Geoffrey D.; Dowling, N. Maritza; Schneck, Carrie

    2008-01-01

    In this article, the authors report achievement outcomes of a multisite cluster randomized field trial of Open Court Reading 2005 (OCR), a K-6 literacy curriculum published by SRA/McGraw-Hill. The participants are 49 first-grade through fifth-grade classrooms from predominantly minority and poor contexts across the nation. Blocking by grade level…

  14. Hydrological modeling using a multi-site stochastic weather generator

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Weather data is usually required at several locations over a large watershed, especially when using distributed models for hydrological simulations. In many applications, spatially correlated weather data can be provided by a multi-site stochastic weather generator which considers the spatial correl...

  15. The clustering of galaxies in the completed SDSS-III Baryon Oscillation Spectroscopic Survey: Observational systematics and baryon acoustic oscillations in the correlation function

    NASA Astrophysics Data System (ADS)

    Ross, Ashley J.; Beutler, Florian; Chuang, Chia-Hsun; Pellejero-Ibanez, Marcos; Seo, Hee-Jong; Vargas-Magaña, Mariana; Cuesta, Antonio J.; Percival, Will J.; Burden, Angela; Sánchez, Ariel G.; Grieb, Jan Niklas; Reid, Beth; Brownstein, Joel R.; Dawson, Kyle S.; Eisenstein, Daniel J.; Ho, Shirley; Kitaura, Francisco-Shu; Nichol, Robert C.; Olmstead, Matthew D.; Prada, Francisco; Rodríguez-Torres, Sergio A.; Saito, Shun; Salazar-Albornoz, Salvador; Schneider, Donald P.; Thomas, Daniel; Tinker, Jeremy; Tojeiro, Rita; Wang, Yuting; White, Martin; Zhao, Gong-bo

    2016-09-01

    We present baryon acoustic oscillation (BAO) scale measurements determined from the clustering of 1.2 million massive galaxies with redshifts 0.2 < z < 0.75 distributed over 9300 square degrees, as quantified by their redshift-space correlation function. In order to facilitate these measurements, we define, describe, and motivate the selection function for galaxies in the final data release (DR12) of the SDSS III Baryon Oscillation Spectroscopic Survey (BOSS). This includes the observational footprint, masks for image quality and Galactic extinction, and weights to account for density relationships intrinsic to the imaging and spectroscopic portions of the survey. We simulate the observed systematic trends in mock galaxy samples and demonstrate that they impart no bias on baryon acoustic oscillation (BAO) scale measurements and have a minor impact on the recovered statistical uncertainty. We measure transverse and radial BAO distance measurements in 0.2 < z < 0.5, 0.5 < z < 0.75, and (overlapping) 0.4 < z < 0.6 redshift bins. In each redshift bin, we obtain a precision that is 2.7 per cent or better on the radial distance and 1.6 per cent or better on the transverse distance. The combination of the redshift bins represents 1.8 per cent precision on the radial distance and 1.1 per cent precision on the transverse distance. This paper is part of a set that analyses the final galaxy clustering dataset from BOSS. The measurements and likelihoods presented here are combined with others in Alam et al. (2016) to produce the final cosmological constraints from BOSS.

  16. Photometric and Spectroscopic Analysis of Classical Novae: An Examination of Their Observational Characteristics and Greater Astronomical Impact

    NASA Astrophysics Data System (ADS)

    Helton, Lorren Andrew

    2010-12-01

    Classical novae (CNe) are violent thermonuclear explosions arising on the surface of white dwarfs in binary systems and are contributors to the chemical evolution of the interstellar medium through the production and ejection of copious amounts of metal-rich material. Observations and modeling of CNe eruptions illuminate numerous fundamental processes of astrophysical interest, including non-equilibrium thermonuclear runaway, radiative processes in dynamic nebular environments, binary star interaction, as well as dust condensation and grain growth. Here I summarize key findings from selected Galactic CNe observed as part of a 5 year, panchromatic optical/infrared observing campaign using Spitzer, Gemini, and other ground based optical facilities. In particular, I present detailed analysis of nova V1065 Centauri, including photoionization analysis of the emission lines, which enabled the derivation of abundances in the ejecta, and radiative transport modeling of the dust emission features, which allowed determination of the composition and characteristics of the dust in this system. I present analysis of three novae, V1974 Cygni, V382 Velorum, and V1494 Aquilae, observed from 4.4--15.5 years after outburst, discuss the characteristics of the nebulae at these late times, and estimate the abundances in their ejecta. In the case of V1494 Aql, I also report the first detection of neon. Finally, I present observations of three novae, DZ Crucis, V2361 Cygni, and V2362 Cygni, that exhibited unidentified infrared (UIR) features in their mid-infrared spectra, which exhibited unusual characteristics. I relate these features to other dusty novae in which features with similar characteristics were observed, and discuss possible sources for the UIR carriers. Analysis of the data obtained in the CNe monitoring campaign presented here highlights the need for synoptic observations obtained with broad wavelength coverage. Observations of V1065 Cen, which exhibited spectra rich in

  17. Replication and Comparison of the Newly Proposed ADOS-2, Module 4 Algorithm in ASD without ID: A Multi-Site Study

    ERIC Educational Resources Information Center

    Pugliese, Cara E.; Kenworthy, Lauren; Bal, Vanessa Hus; Wallace, Gregory L.; Yerys, Benjamin E.; Maddox, Brenna B.; White, Susan W.; Popal, Haroon; Armour, Anna Chelsea; Miller, Judith; Herrington, John D.; Schultz, Robert T.; Martin, Alex; Anthony, Laura Gutermuth

    2015-01-01

    Recent updates have been proposed to the Autism Diagnostic Observation Schedule-2 Module 4 diagnostic algorithm. This new algorithm, however, has not yet been validated in an independent sample without intellectual disability (ID). This multi-site study compared the original and revised algorithms in individuals with ASD without ID. The revised…

  18. Spectroscopic observations of the peculiar low-mass X-ray binary XSS J12270-4859

    NASA Astrophysics Data System (ADS)

    de Martino, D.; Velazquez, J. Casares; Mason, E.; Kotze, M.; Buckley, D. A. H.; Bonnet-Bidaud, J.-M.; Belloni, T.; Mouchet, M.; Falanga, M.

    2013-12-01

    The enigmatic low-mass X-ray binary XSS J12270-4859 associated to the Fermi/LAT Gamma ray source 1FGL 1227.9-4852/2FGL 1227.7-4853 (de Martino et al. 2010, A&A 515, A25; Hill et al. 2011, MNRAS 415, 235; de Martino et al. 2013, A&A 550, A89) was extensively observed from radio to gamma rays but its orbital period is still unknown. Pretorius (2009, MNRAS, 395, 386) did not find a period in time resolved optical observations.

  19. High-dispersion spectroscopic observations of Venus during 1968 and 1969 II. The carbon-dioxide band at 8689A

    NASA Technical Reports Server (NTRS)

    Schorn, R. A. J.; Woszczyk, A.; Young, L. D. G.

    1974-01-01

    Thirty well-exposed photographic plates showing the spectrum of the carbon dioxide band at 8689A in the atmosphere of Venus were obtained during 1968 and 1969. All spectra were obtained at a dispersion of 2 A/mm for Venus phase angles varying from 10 deg. to 126 deg. Rotational temperatures ranging from 236 K to 274 K were found. The average value of the rotational temperature is 246 + or - 1 K (one standard deviation); for 1967 observations, the rotational temperatures ranged from 222 to 248 K, with an average value of 238 + or - 4 K. The variation of the equivalent width of the 8689A band, with Venus phase angle, was very similar for the two sets of observations (53 plates). The temporal variations, of approximately 30 percent, were comparable with the phase variations over this limited range of phase angle.

  20. Thermal infrared spectroscopic observations of Mars from the Kuiper Airborne Observatory (KAO): Constraints on past climates and weathering products

    NASA Technical Reports Server (NTRS)

    Roush, Ted L.; Pollack, James B.; Witteborn, Fred C.; Bregman, Jesse D.; Bell, James F., III; Sitton, Bradley

    1995-01-01

    Spectral observations providing evidence for the presence of volatile-bearing minerals on the surface of Mars were obtained in 1988 and 1990 from the KAO. The 1988 data suggest the presence of 1-3 weight percent (wt%) of carbonate/bicarbonate and 10-15 wt% sulfate/bisulfate associated with martian atmospheric dust. Estimates of the optical depths are approximately 0.60 and approximately 0.35 in 1988 and 1990, respectively.

  1. A nested multisite daily rainfall stochastic generation model

    NASA Astrophysics Data System (ADS)

    Srikanthan, Ratnasingham; Pegram, Geoffrey G. S.

    2009-06-01

    SummaryThis paper describes a nested multisite daily rainfall generation model which preserves the statistics at daily, monthly and annual levels of aggregation. A multisite two-part daily model is nested in multisite monthly, then annual models. A multivariate set of fourth order Markov chains is used to model the daily occurrence of rainfall; the daily spatial correlation in the occurrence process is handled by using suitably correlated uniformly distributed variates via a Normal Scores Transform (NST) obtained from a set of matched multinormal pseudo-random variates, following Wilks [Wilks, D.S., 1998. Multisite generalisation of a daily stochastic precipitation generation model. Journal of Hydrology 210, 178-191]; we call it a hidden covariance model. A spatially correlated two parameter gamma distribution is used to obtain the rainfall depths; these values are also correlated via a specially matched hidden multinormal process. For nesting, the generated daily rainfall sequences at all the sites are aggregated to monthly rainfall values and these values are modified by a set of lag-1 autoregressive multisite monthly rainfall models. The modified monthly rainfall values are aggregated to annual rainfall and these are then modified by a lag-1 autoregressive multisite annual model. This nesting process ensures that the daily, monthly and annual means and covariances are preserved. The model was applied to a region with 30 rainfall sites, one of the five sets reported by Srikanthan [Srikanthan, R., 2005. Stochastic Generation of Daily Rainfall Data at a Number of Sites. Technical Report 05/7, CRC for Catchment Hydrology. Monash University, 66p]. A comparison of the historical and generated statistics shows that the model preserves all the important characteristics of rainfall at the daily, monthly and annual time scales, including the spatial structure. There are some outstanding features that need to be improved: depths of rainfall on isolated wet days and

  2. {sup 13}C-METHYL FORMATE: OBSERVATIONS OF A SAMPLE OF HIGH-MASS STAR-FORMING REGIONS INCLUDING ORION-KL AND SPECTROSCOPIC CHARACTERIZATION

    SciTech Connect

    Favre, Cécile; Bergin, Edwin A.; Crockett, Nathan R.; Neill, Justin L.; Carvajal, Miguel; Field, David; Jørgensen, Jes K.; Bisschop, Suzanne E.; Brouillet, Nathalie; Despois, Didier; Baudry, Alain; Kleiner, Isabelle; Margulès, Laurent; Huet, Thérèse R.; Demaison, Jean E-mail: miguel.carvajal@dfa.uhu.es

    2015-01-01

    We have surveyed a sample of massive star-forming regions located over a range of distances from the Galactic center for methyl formate, HCOOCH{sub 3}, and its isotopologues H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3}. The observations were carried out with the APEX telescope in the frequency range 283.4-287.4 GHz. Based on the APEX observations, we report tentative detections of the {sup 13}C-methyl formate isotopologue HCOO{sup 13}CH{sub 3} toward the following four massive star-forming regions: Sgr B2(N-LMH), NGC 6334 IRS 1, W51 e2, and G19.61-0.23. In addition, we have used the 1 mm ALMA science verification observations of Orion-KL and confirm the detection of the {sup 13}C-methyl formate species in Orion-KL and image its spatial distribution. Our analysis shows that the {sup 12}C/{sup 13}C isotope ratio in methyl formate toward the Orion-KL Compact Ridge and Hot Core-SW components (68.4 ± 10.1 and 71.4 ± 7.8, respectively) are, for both the {sup 13}C-methyl formate isotopologues, commensurate with the average {sup 12}C/{sup 13}C ratio of CO derived toward Orion-KL. Likewise, regarding the other sources, our results are consistent with the {sup 12}C/{sup 13}C in CO. We also report the spectroscopic characterization, which includes a complete partition function, of the complex H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3} species. New spectroscopic data for both isotopomers H{sup 13}COOCH{sub 3} and HCOO{sup 13}CH{sub 3}, presented in this study, have made it possible to measure this fundamentally important isotope ratio in a large organic molecule for the first time.

  3. NEAR-CONTEMPORANEOUS OPTICAL SPECTROSCOPIC AND INFRARED PHOTOMETRIC OBSERVATIONS OF CANDIDATE HERBIG Ae/Be STARS IN THE MAGELLANIC CLOUDS

    SciTech Connect

    Rush, Bradley W.; Bjorkman, Karen S.; Wisniewski, John P. E-mail: Karen.Bjorkman@utoledo.edu

    2011-08-15

    We present near-IR (J, H, Ks) photometry for 27 of the 28 candidate Herbig Ae/Be stars in the Small and Large Magellanic Clouds (SMC and LMC) identified via the EROS1 and EROS2 surveys as well as near-contemporaneous optical (H{alpha}) spectroscopy for 21 of these 28 candidates. Our observations extend previous efforts to determine the evolutionary status of these objects. We compare the IR brightness and colors of a subset of our sample with archival ground-based IR data and find evidence of statistically significant photometric differences for EROS LMC HAeBe candidates (ELHC) 5, 7, 12, 18, and 21 in one or more filters. In all cases, these near-IR photometric variations exhibit a gray color as compared to earlier epoch data. The {approx}1 mag IR brightening and minimal change in the H{alpha} emission strength we observe in ELHC 7 is consistent with previous claims that it is a UX Ori type HAe/Be star, which is occasionally obscured by dust clouds. We also detect a {approx}1 mag IR brightening of ELHC 12, but find little evidence of a similar large-scale change in its H{alpha} line strength, suggesting that its behavior could also be caused by a UX Ori-like event. The {approx}0.5 mag IR variability we observe for ELHC 21, which also exhibited little evidence of a change in its H{alpha} emission strength, could conceivably be caused by a major recent enhancement in the density of the inner disk region of a classical Be star. We also report the first near-IR photometry for two EROS SMC HAeBe Candidates (ESHC) stars and the first H{alpha} spectroscopy for one ELHC and five ESHC stars. Although H{alpha} emission is detected in all of these new observations, they do not exhibit a strong near-IR excess. It is therefore possible that many of these objects may be classical Be stars rather than Herbig Ae/Be stars.

  4. Pulsation in the atmosphere of the roAp star HD 24712. I. Spectroscopic observations and radial velocity measurements

    NASA Astrophysics Data System (ADS)

    Ryabchikova, T.; Sachkov, M.; Weiss, W. W.; Kallinger, T.; Kochukhov, O.; Bagnulo, S.; Ilyin, I.; Landstreet, J. D.; Leone, F.; Lo Curto, G.; Lüftinger, T.; Lyashko, D.; Magazzù, A.

    2007-02-01

    Aims:We have investigated the structure of the pulsating atmosphere of one of the best studied rapidly oscillating Ap stars, HD 24712. Methods: For this purpose we analyzed spectra collected during 2001-2004. An extensive data set was obtained in 2004 simultaneously with the photometry of the Canadian MOST mini-satellite. This allows us to connect directly atmospheric dynamics observed as radial velocity variations with light variations seen in photometry. Results: We directly derived for the first time and for different chemical elements, respectively ions, phase shifts between photometric and radial velocity pulsation maxima indicating, as we suggest, different line formation depths in the atmosphere. This allowed us to estimate for the first time the propagation velocity of a pulsation wave in the outer stellar atmosphere of a roAp star to be slightly lower than the sound speed. We confirm large pulsation amplitudes (150-400 m s-1) for REE lines and the Hα core, while spectral lines of the other elements (Mg, Si, Ca, and Fe-peak elements) have nearly constant velocities. We did not find different pulsation amplitudes and phases for the lines of rare-earth elements before and after the Balmer jump, which supports the hypothesis of REE concentration in the upper atmosphere above the hydrogen line-forming layers. We also discuss radial velocity amplitudes and phases measured for individual spectral lines as tools for a 3D tomography of the atmosphere of HD 24712. Based on observations collected at the Canada-France-Hawaii Telescope (CFHT), at the Nordic Optical Telescope (NOT), at the European Southern Observatory, Paranal, Chile, (DDT-274.D-5011), at the Telescopio Nazionale Galileo (TNG), and from MOST, a Canadian Space Agency mission operated jointly by Dynacon, Inc., the University of Toronto Institute of Aerospace Studies, and the University of British Columbia, with assistance from the University of Vienna. Tables 4, 5 and Fig. 9 are only available in

  5. Compact Solar Spectroscopic Column CO2, CH4, H2O and HOD Observations: Performance Evaluation at TCCON Sites

    NASA Astrophysics Data System (ADS)

    Butterfield, Z.; Lindenmaier, R.; Dubey, M. K.; Hedelius, J.; Wunch, D.; Wennberg, P. O.; Podolske, J. R.; Iraci, L. T.; Hillyard, P. W.; Hase, F.

    2014-12-01

    Monitoring, reporting and verification (MRV) of natural sources and sinks and anthropogenic emission of carbon dioxide (CO2) and methane (CH4) are crucial to predict climate change and develop transparent accounting policies to contain climate forcing. Remote sensing technologies are beginning to monitor CO2 and CH4 from ground and space (OCO-2 and GOSAT) with solar spectroscopy enabling direct MRV. However, current ground based coverage is sparse due to the need for large and expensive high-resolution spectrometers that are part of the Total Column Carbon Observing Network (TCCON, Bruker 125HR). This limits our MRV and satellite validation abilities, both regionally and globally. There are striking monitoring gaps in Asia, South America and Africa where the CO2 emissions are growing and there is a large uncertainty in fluxes from land use change, biomass burning and rainforest vulnerability. To fill this gap we evaluate the precision, accuracy and stability of our new compact, affordable and easy to use low-resolution spectrometer (Bruker EM27SUN) by comparing it with the much larger high-resolution TCCON instruments for column CO2, CH4, H2O and HOD. Results from Four Corners, Los Alamos, Caltech and Dryden-Armstrong sites show that our EM27SUN captures the variability of the aforementioned constituents very well, but has low and high offsets for CO2 and CH4, respectively. These off-the-shelf spectrometers should dramatically expand the coverage of regional column CO2 and CH4 observations, particularly in gap regions that include the rainforest. We will present opportunities that we are exploring to help enable transparent and reliable MRV and measurement of the coupled water-carbon cycle in tropical ecosystems.

  6. Spectroscopic and photometric observations of the selected Algol-type binaries - II. V2080 Cygni and V2365 Ophiuchi

    NASA Astrophysics Data System (ADS)

    Ibanoǧlu, C.; Evren, S.; Taş, G.; Çakırlı, Ö.; Bozkurt, Z.; Afşar, M.; Frasca, A.; Sipahi, E.; Dal, H. A.; Özdarcan, O.; Çamurdan, D. Zengin; Çamurdan, M.

    2008-02-01

    This paper is the second in the planned series of investigations. We present new radial velocities and photometric observations of V2080 Cyg and V2365 Oph. New UBV photometric data and radial velocities were analysed for the systems' parameters. While V2080 Cyg consists of two nearly equal F-type main-sequence stars, V2365 Oph has two different components, namely an early A-type primary and a G-type secondary star. New ephemerides are calculated for both systems. The masses of the component stars have been derived as 1.19 +/- 0.02 and 1.16 +/- 0.02Msolar for V2080 Cyg and 1.97 +/- 0.02 and 1.06 +/- 0.01Msolar for V2365 Oph. The effective temperatures and reddening of the systems have been estimated from Johnson wide-band UBV photometric calibrations. The radii have been measured by simultaneous fitting the UBV light curves using Wilson-Devinney code and are 1.60 +/- 0.01Rsolar for both components of V2080 Cyg and 2.19 +/- 0.01 and 0.934 +/- 0.004Rsolar for V2365 Oph. The absolute parameters of the stars in both systems lie within the same ranges in the mass-radius, mass-effective temperature, mass-luminosity and luminosity-effective temperature planes as in detached Algol systems. A comparison between the properties of the systems of interest and the predictions of theoretical evolutionary models is undertaken in the logg-logTeff, logR- logM and radius-log age diagrams. The model predictions match the measured properties of V2080 Cyg for an age of about 5.6 Gyr and a `solar' metal abundance (Z = 0.019), indicating the components near the end of their core hydrogen-burning phases. However, the position of the components of V2365 Oph on the Hertzsprung-Russell (HR) diagram is best reproduced with evolutionary models for somewhat metal-deficient (Z = 0.004) stars. We found an age of about 700 Myr, with the primary component slightly evolved off the zero-age main-sequence and the secondary one still very close to it. From the basic stellar parameters we have also

  7. Transient IR Spectroscopic Observation of Singlet and Triplet States of 2-Nitrofluorene: Revisiting the Photophysics of Nitroaromatics.

    PubMed

    Larsen, Martin A B; Thøgersen, Jan; Stephansen, Anne B; Peon, Jorge; Sølling, Theis I; Keiding, Søren R

    2016-01-14

    The dynamics of 2-nitrofluorene (2-NF) in deuterated acetonitrile is studied using UV pump, IR probe femtosecond transient absorption spectroscopy. Upon excitation to the vibrationally excited S1 state, the excited-state population of 2-NF branches into two different relaxation pathways. One route leads to intersystem crossing (ISC) to the triplet manifold within a few hundred femtoseconds and the other to internal conversion (IC) to the ground state. The experiments indicate that after relaxation to the energetic minimum on S1, 2-NF undergoes internal conversion to the ground state in about 15 ps. IC within the triplet manifold is also observed as the initially populated triplet state relaxes to T1 in about 6 ps. Rotational anisotropy measurements corroborate the assignment of the transient IR frequencies and indicate a rotational diffusion time of 2-NF in the solvent of about 14 ps. The combined set of results provides a unified picture of the dynamics in photoexcited 2-NF. This to our knowledge is the first example using femtosecond vibrational spectroscopy for the study of the fundamental photoinduced processes in nitroaromatic compounds. PMID:26669456

  8. Proton Adsorption onto Alumina: Extension of Multisite Complexation (MUSIC) Theory.

    PubMed

    Nagashima; Blum

    1999-09-01

    The adsorption isotherm of protons onto a commercial gamma-alumina sample was determined in aqueous nitric acid with sodium nitrate as a background electrolyte. Three discrete regions could be discerned in the log-log plots of the proton isotherm determined at the solution pH 5 to 2. The multisite complexation (MUSIC) model was modified to analyze the simultaneous adsorption of protons onto various kinds of surface species. Copyright 1999 Academic Press. PMID:10441408

  9. Proton adsorption onto alumina: extension of multisite complexation (MUSIC) theory

    SciTech Connect

    Nagashima, K.; Blum, F.D.

    1999-09-01

    The adsorption isotherm of protons onto a commercial {gamma}-alumina sample was determined in aqueous nitric acid with sodium nitrate as a background electrolyte. Three discrete regions could be discerned in the log-log plots of the proton isotherm determined at the solution pH 5 to 2. The multisite complexation (MUSIC) model was modified to analyze the simultaneous adsorption of protons onto various kinds of surface species.

  10. Proton Adsorption onto Alumina: Extension of Multisite Complexation (MUSIC) Theory.

    PubMed

    Nagashima; Blum

    1999-09-01

    The adsorption isotherm of protons onto a commercial gamma-alumina sample was determined in aqueous nitric acid with sodium nitrate as a background electrolyte. Three discrete regions could be discerned in the log-log plots of the proton isotherm determined at the solution pH 5 to 2. The multisite complexation (MUSIC) model was modified to analyze the simultaneous adsorption of protons onto various kinds of surface species. Copyright 1999 Academic Press.

  11. Observational and laboratory studies of optical properties of black and brown carbon particles in the atmosphere using spectroscopic techniques

    NASA Astrophysics Data System (ADS)

    Nakayama, Tomoki; Matsumi, Yutaka

    2015-04-01

    Light absorption and scattering by aerosols are as an important contributor to radiation balance in the atmosphere. Black carbon (BC) is considered to be the most potent light absorbing material in the visible region of the spectrum, although light absorbing organic carbon (brown carbon or BrC) and mineral dust may also act as sources of significant absorption, especially in the ultraviolet (UV) and shorter visible wavelength regions. The optical properties of such particles depend on wavelength, particle size and shape, morphology, coating, and complex refractive index (or chemical composition), and therefore accurate in situ measurements of the wavelength dependence of the optical properties of particles are needed. Recently, cavity ring-down spectroscopy (CRDS) and photoacoustic spectroscopy (PAS) have been used for the direct measurements of extinction and absorption coefficients of particles suspended in air. We have applied these techniques to the observational studies of optical properties of BC and BrC in an urban site in Japan and to the laboratory studies of optical properties of secondary organic aerosols (SOAs) generated from a variety of biogenic and anthropogenic volatile organic compounds and those of diesel exhaust particles (DEPs). In the presentation, the basic principles of these techniques and the results obtained in our studies and in the recent literatures will be overviewed. References Guo, X. et al., Measurement of the light absorbing properties of diesel exhaust particles using a three-wavelength photoacoustic spectrometer, Atmos. Environ., 94, 428-437 (2014). Nakayama, T. et al., Measurements of aerosol optical properties in central Tokyo during summertime using cavity ring-down spectroscopy: Comparison with conventional techniques, Atmos. Environ., 44, 3034-3042 (2010). Nakayama, T. et al., Laboratory studies on optical properties of secondary organic aerosols generated during the photooxidation of toluene and the ozonolysis of alpha

  12. Study of diatoms/aqueous solution interface. I. Acid-base equilibria and spectroscopic observation of freshwater and marine species

    NASA Astrophysics Data System (ADS)

    Gélabert, A.; Pokrovsky, O. S.; Schott, J.; Boudou, A.; Feurtet-Mazel, A.; Mielczarski, J.; Mielczarski, E.; Mesmer-Dudons, N.; Spalla, O.

    2004-10-01

    This work reports on a concerted study of diatom-water interfaces for two marine planktonic ( Thalassiosira weissflogii= TW, Skeletonema costatum= SC) and two freshwater periphytic species ( Achnanthidium minutissimum= AMIN, Navicula minima= NMIN). Proton surface adsorption was measured at 25°C, pH of 3 to 11 and ionic strength of 0.001 to 1.0 M via potentiometric titration using a limited residence time reactor. Electrophoretic mobility of living cells and their frustules was measured as a function of pH and ionic strength. Information on the chemical composition and molecular structure of diatoms surfaces was obtained using FT-IR (in situ attenuated total reflectance) and X-ray Photoelectron Spectroscopy (XPS). The surface area of living cells and their frustules in aqueous solutions was quantified using Small Angle X-ray Scattering Spectroscopy (SAXS). These observations allowed us to identify the nature and to determine the concentration of the major surface functional groups (carboxyl, amine and silanol) responsible for the amphoteric behavior of cell surfaces in aqueous solutions. Taking into account the relative proportion of surface sites inferred from XPS and FT-IR measurements, a surface complexation model of diatom-solution interfaces was generated on the basis of surface titration results. The cell-normalized ratios of the three major surface sites {>COOH}: {>NH 3}: {>SiOH} are 1:1:0.1, 1:10:0, 1:1:0.4 and 1:1:0.3 for TW, SC, AMIN and NMIN, respectively. The total amount of proton/hydroxyl active surface sites for investigated species ranges from 1 (NMIN) to 9 (SC) mmol/g dry weight. Normalization of these site densities to the area of siliceous skeleton yields values between 0.3 (NMIN) and 0.9 mmol/m 2 (SC) which are an order of magnitude higher than corresponding values for organic-free frustules or amorphous silica. This suggests that the amphoteric properties and possibly the affinity for metal adsorption of diatom cultures are essentially

  13. Expansion of the gateway multisite recombination cloning toolkit.

    PubMed

    Shearin, Harold K; Dvarishkis, Alisa R; Kozeluh, Craig D; Stowers, R Steven

    2013-01-01

    Precise manipulation of transgene expression in genetic model organisms has led to advances in understanding fundamental mechanisms of development, physiology, and genetic disease. Transgene construction is, however, a precondition of transgene expression, and often limits the rate of experimental progress. Here we report an expansion of the modular Gateway MultiSite recombination-cloning platform for high efficiency transgene assembly. The expansion includes two additional destination vectors and entry clones for the LexA binary transcription system, among others. These new tools enhance the expression levels possible with Gateway MultiSite generated transgenes and make possible the generation of LexA drivers and reporters with Gateway MultiSite cloning. In vivo data from transgenic Drosophila functionally validating each novel component are presented and include neuronal LexA drivers, LexAop2 red and green fluorescent synaptic vesicle reporters, TDC2 and TRH LexA, GAL4, and QF drivers, and LexAop2, UAS, and QUAS channelrhodopsin2 T159C reporters.

  14. Multiperiod planning tool for multisite pig production systems.

    PubMed

    Nadal-Roig, E; Plà, L M

    2014-09-01

    This paper presents a multiperiod planning tool for multisite pig production systems based on Linear Programming (LP). The aim of the model is to help pig managers of multisite systems in making short-term decisions (mainly related to pig transfers between farms and batch management in fattening units) and mid-term or long-term decisions (according to company targets and expansion strategy). The model skeleton follows the structure of a three-site system that can be adapted to any multisite system present in the modern pig industry. There are three basic phases, namely, piglet production, rearing pigs, and fattening. Each phase involves a different set of farms; therefore, transportation between farms and delivering of pigs to the abattoir are under consideration. The model maximizes the total gross margin calculated from the income of sales to the abattoir and the production costs over the time horizon considered. Production cost depends on each type of farm involved in the process. Parameters like number of farms per phase and distance, farm capacity, reproduction management policies, feeding and veterinary expenses, and transportation costs are taken into account. The model also provides a schedule of transfers between farms in terms of animals to be transported and number of trucks involved. The use of the model is illustrated with a case study based on a real instance of a company located in Catalonia (Spain).

  15. Dynamics of allosteric action in multisite protein modification

    NASA Astrophysics Data System (ADS)

    Milotti, Edoardo; Del Fabbro, Alessio; Dalla Pellegrina, Chiara; Chignola, Roberto

    2007-06-01

    Protein functions in cells may be activated or modified by the attachment of several kinds of chemical groups. While protein phosphorylation, i.e., the attachment of a phosphoryl (PO3-) group, is the most studied form of protein modification, and is known to regulate the functions of many proteins, protein behavior can also be modified by nitrosylation, acetylation, methylation, etc. A protein can have multiple modification sites, and displays some form of transition only when enough sites are modified. In a previous paper we have modeled the generic equilibrium properties of multisite protein modification [R. Chignola, C. Dalla Pellegrina, A. Del Fabbro, E. Milotti, Physica A 371 (2006) 463] and we have shown that it can account both for sharp, robust thresholds and for information transfer between processes with widely separated timescales. Here we use the same concepts to expand that analysis starting from a dynamical description of multisite modification: we give analytical results for the basic dynamics and numerical results in an example where the modification chain is cascaded with a Michaelis-Menten step. We modify the dynamics and analyze an example with realistic phosphorylation/dephosphorylation steps, and give numerical evidence of the independence of the allosteric effect from the details of the attachment-detachment processes. We conclude that multisite protein modification is dynamically equivalent to the classic allosteric effect.

  16. Multisite ion model in concentrated solutions of divalent cations (MgCl2 and CaCl2): osmotic pressure calculations.

    PubMed

    Saxena, Akansha; García, Angel E

    2015-01-01

    Accurate force field parameters for ions are essential for meaningful simulation studies of proteins and nucleic acids. Currently accepted models of ions, especially for divalent ions, do not necessarily reproduce the right physiological behavior of Ca(2+) and Mg(2+) ions. Saxena and Sept (J. Chem. Theor. Comput. 2013, 9, 3538-3542) described a model, called the multisite-ion model, where instead of treating the ions as an isolated sphere, the charge was split into multiple sites with partial charge. This model provided accurate inner shell coordination of the ion with biomolecules and predicted better free energies for proteins and nucleic acids. Here, we expand and refine the multisite model to describe the behavior of divalent ions in concentrated MgCl2 and CaCl2 electrolyte solutions, eliminating the unusual ion-ion pairing and clustering of ions which occurred in the original model. We calibrate and improve the parameters of the multisite model by matching the osmotic pressure of concentrated solutions of MgCl2 to the experimental values and then use these parameters to test the behavior of CaCl2 solutions. We find that the concentrated solutions of both divalent ions exhibit the experimentally observed behavior with correct osmotic pressure, the presence of solvent separated ion pairs instead of direct ion pairs, and no aggregation of ions. The improved multisite model for (Mg(2+) and Ca(2+)) can be used in classical simulations of biomolecules at physiologically relevant salt concentrations.

  17. Spectroscopic Observations of the Planets

    NASA Technical Reports Server (NTRS)

    Owen, Tobias

    1998-01-01

    During the period under review, the main effort of the research supported by this grant was concentrated on Titan, Iapetus, and two comets, Comet Hyakutake and Comet Hale-Bopp. Significant discoveries were made in each case as summarized in the report.

  18. Spectroscopic Observations of UU Cas

    NASA Astrophysics Data System (ADS)

    Markov, H.; Vince, I.; Markova, N.; Djurasevic, G.

    2010-09-01

    High dispersion (R = 30000) spectra of the eclipsing binary system UU Cas are presented for the first time. Spectra covering 15 different phases were taken in two spectral regions - the vicinity of H_α and another centered on 5800Å. Seven spectral lines were identified in common. Four of them belonging to the brighter component were used to construct radial velocity curve. Some constrains on the spectral classification of the components are presented.

  19. Hard X-ray Spectroscopic, Microwave and H-alpha Linear Polarization Studies with Hard X-Ray Observations from HESSI

    NASA Technical Reports Server (NTRS)

    Kiplinger, Alan L.

    2005-01-01

    The Principal Investigator (P.I.) has been pursuing a three year grant under NASA's Sun-Earth Connection Guest Investigator Program in support of the Ramaty High Energy Solar Spectroscopic Imager (RHESSI). An objective of these efforts is to combine X-ray and other data on solar flares, coronal mass ejections and interplanetary particle events in order to obtain a more comprehensive recognition of signatures, and understanding of interplanetary proton events. Thus, part of these efforts are to investigate if signatures seen in hard X-rays and microwaves can lead to better predictions of interplanetary proton events that can be dangerous to astronauts and spacecraft. The original proposal was written in May, 2000 and it discusses a three-pronged approach for data comparisons with three new types of instrumentation observing at X-ray, microwave and optical wavelengths. The major impetus behind this work and the proposal is that the P.I. discovered a strong correlation between a particular type of hard X-ray signature seen in spectral evolutions and interplanetary proton events (Kiplinger, 1995). The basic signature is that hard X-ray flux peaks either exhibit spectra that soften on their decays (Le. show fewer and fewer high energy X-rays with time) or they harden during decays (i.e. high energy X-rays decay significantly slower that lower energy X-rays). This signature is called progressive hardening. Studies were conducted over an eight-year period of data from the Hard X-Ray Burst Spectrometer (HXRBS) of the Solar maximum mission. Out of the 750 well observed flares studied, 41 flares had major associated proton events. Of these, 29 events were predicted on the basis of progressive hardening for a hit rate of 71%. The 152 largest flares had a hit rate of 82%.

  20. Candidate Water Vapor Lines to Locate the H2O Snowline through High-dispersion Spectroscopic Observations. I. The Case of a T Tauri Star

    NASA Astrophysics Data System (ADS)

    Notsu, Shota; Nomura, Hideko; Ishimoto, Daiki; Walsh, Catherine; Honda, Mitsuhiko; Hirota, Tomoya; Millar, T. J.

    2016-08-01

    Inside the H2O snowline of protoplanetary disks, water evaporates from the dust-grain surface into the gas phase, whereas it is frozen out onto the dust in the cold region beyond the snowline. H2O ice enhances the solid material in the cold outer part of a disk, which promotes the formation of gas-giant planet cores. We can regard the H2O snowline as the surface that divides the regions between rocky and gaseous giant planet formation. Thus observationally measuring the location of the H2O snowline is crucial for understanding the planetesimal and planet formation processes, and the origin of water on Earth. In this paper, we find candidate water lines to locate the H2O snowline through future high-dispersion spectroscopic observations. First, we calculate the chemical composition of the disk and investigate the abundance distributions of H2O gas and ice, and the position of the H2O snowline. We confirm that the abundance of H2O gas is high not only in the hot midplane region inside the H2O snowline but also in the hot surface layer of the outer disk. Second, we calculate the H2O line profiles and identify those H2O lines that are promising for locating the H2O snowline: the identified lines are those that have small Einstein A coefficients and high upper state energies. The wavelengths of the candidate H2O lines range from mid-infrared to sub-millimeter, and they overlap with the regions accessible to the Atacama Large Millimeter/sub-millimeter Array and future mid-infrared high-dispersion spectrographs (e.g., TMT/MICHI, SPICA).

  1. Spectroscopic detection

    DOEpatents

    Woskov, Paul P.; Hadidi, Kamal

    2003-01-01

    In embodiments, spectroscopic monitor monitors modulated light signals to detect low levels of contaminants and other compounds in the presence of background interference. The monitor uses a spectrometer that includes a transmissive modulator capable of causing different frequency ranges to move onto and off of the detector. The different ranges can include those with the desired signal and those selected to subtract background contributions from those with the desired signal. Embodiments of the system are particularly useful for monitoring metal concentrations in combustion effluent.

  2. Spectroscopic Classifications of Optical Transients with SOAR

    NASA Astrophysics Data System (ADS)

    Foley, R. J.; Hounsell, R. A.; Downing, S.; Pan, Y.-C.; Scolnic, D.; Jha, S. W.; Rest, A.; Smith, K. W.; Wright, D.; Smartt, S. J.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.

    2015-07-01

    We report the following classifications of optical transients from spectroscopic observations with the Goodman spectrograph (wavelength range 3100 - 7100) on the Southern Astrophysical Research (SOAR) telescope.

  3. Observations of the Neupert Effect with the Solar Dynamics Observatory, Reuven Ramaty High Energy Solar Spectroscopic Imager, and Geostationary Operational Environmental Satellite

    NASA Astrophysics Data System (ADS)

    Schonfeld, Sam J.; Chamberlin, P. C.

    2012-01-01

    The Neupert Effect is an empirically observed correlation between the hard X-rays (HXR) and the time derivative of soft X-rays (SXR) emitted during the impulsive phase of a solar flare. According to standard models of magnetic reconnection driven flares, accelerated electron beams are responsible for creating the HXR Bremsstrahlung radiation in the Transition Region and upper Chromosphere. This energy input should also heat the relatively low-temperature Chromospheric plasma, increasing the intensity of extreme ultraviolet (EUV) emission lines. The launch of the Extreme Ultraviolet Variability Experiment (EVE) on board the Solar Dynamics observatory (SDO) has for the first time provided measurements of the solar irradiance spectra with 0.1 nm spectral resolution over the range 6.5-37 nm at 10-second cadence and nearly 100% duty cycle. Comparisons were made using the EUV spectral data from EVE, SXR measured by the X-Ray Spectrometer (XRS) on the Geostationary Operational Environmental Satellites (GOES), and HXR recorded with the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI). The first focus of the investigation looked at the timing of the HXR, time derivative of soft X-ray, and the Helium-II 304Å doublet. The second focus compared He II images taken by the Atmospheric Imaging Assembly (AIA) (also on SDO) to x-ray images taken by RHESSI to compare the spatial location and area of the lower atmospheric energy emissions. We investigated all M class and above flares between May 1st 2010 and June 1st 2011 with complete coverage by all three instruments totaling 31 events. Of these, 77% (24) showed the expected Neupert Effect with 70% (17) of these events also displaying He-II profiles consistent with the electron beam heating model. This collaboration was organized through the SESI internship program at GSFC and funded by the Catholic University of America.

  4. SPECTROSCOPIC OBSERVATIONS OF SN 2012fr: A LUMINOUS, NORMAL TYPE Ia SUPERNOVA WITH EARLY HIGH-VELOCITY FEATURES AND A LATE VELOCITY PLATEAU

    SciTech Connect

    Childress, M. J.; Scalzo, R. A.; Sim, S. A.; Tucker, B. E.; Yuan, F.; Schmidt, B. P.; Cenko, S. B.; Filippenko, A. V.; Silverman, J. M.; Contreras, C.; Hsiao, E. Y.; Phillips, M.; Morrell, N.; Jha, S. W.; McCully, C.; Anderson, J. P.; De Jaeger, T.; Forster, F.; Benetti, S.; Bufano, F.; and others

    2013-06-10

    We present 65 optical spectra of the Type Ia SN 2012fr, 33 of which were obtained before maximum light. At early times, SN 2012fr shows clear evidence of a high-velocity feature (HVF) in the Si II {lambda}6355 line that can be cleanly decoupled from the lower velocity ''photospheric'' component. This Si II {lambda}6355 HVF fades by phase -5; subsequently, the photospheric component exhibits a very narrow velocity width and remains at a nearly constant velocity of {approx}12,000 km s{sup -1} until at least five weeks after maximum brightness. The Ca II infrared triplet exhibits similar evidence for both a photospheric component at v Almost-Equal-To 12,000 km s{sup -1} with narrow line width and long velocity plateau, as well as an HVF beginning at v Almost-Equal-To 31,000 km s{sup -1} two weeks before maximum. SN 2012fr resides on the border between the ''shallow silicon'' and ''core-normal'' subclasses in the Branch et al. classification scheme, and on the border between normal and high-velocity Type Ia supernovae (SNe Ia) in the Wang et al. system. Though it is a clear member of the ''low velocity gradient'' group of SNe Ia and exhibits a very slow light-curve decline, it shows key dissimilarities with the overluminous SN 1991T or SN 1999aa subclasses of SNe Ia. SN 2012fr represents a well-observed SN Ia at the luminous end of the normal SN Ia distribution and a key transitional event between nominal spectroscopic subclasses of SNe Ia.

  5. Multi-Sited Global Ethnography and Travel: Gendered Journeys in Three Registers

    ERIC Educational Resources Information Center

    Epstein, Debbie; Fahey, Johannah; Kenway, Jane

    2013-01-01

    This paper joins a barely begun conversation about multi-sited and global ethnography in educational research; a conversation that is likely to intensify along with growing interest in the links between education, globalisation, internationalisation and transnationalism. Drawing on an ongoing multi-sited global ethnography of elite schools and…

  6. A Multisite-Binding Switchable Fluorescent Probe for Monitoring Mitochondrial ATP Level Fluctuation in Live Cells.

    PubMed

    Wang, Lu; Yuan, Lin; Zeng, Xian; Peng, Juanjuan; Ni, Yong; Er, Jun Cheng; Xu, Wang; Agrawalla, Bikram Keshari; Su, Dongdong; Kim, Beomsue; Chang, Young-Tae

    2016-01-26

    Adenosine triphosphate (ATP), commonly produced in mitochondria, is required by almost all the living organisms; thus fluorescent probes for monitoring mitochondrial ATP levels fluctuation are essential and highly desired. Herein, we report a multisite-binding switchable fluorescent probe, ATP-Red 1, which selectively and rapidly responds to intracellular concentrations of ATP. Live-cell imaging indicated that ATP-Red 1 mainly localized to mitochondria with good biocompatibility and membrane penetration. In particular, with the help of ATP-Red 1, we successfully observed not only the decreased mitochondrial ATP levels in the presence of KCN and starvation state, but also the increased mitochondrial ATP levels in the early stage of cell apoptosis. These results indicate that ATP-Red 1 is a useful tool for investigating ATP-relevant biological processes.

  7. Spectroscopic Binary Stars

    NASA Astrophysics Data System (ADS)

    Batten, A.; Murdin, P.

    2000-11-01

    Historically, spectroscopic binary stars were binary systems whose nature was discovered by the changing DOPPLER EFFECT or shift of the spectral lines of one or both of the component stars. The observed Doppler shift is a combination of that produced by the constant RADIAL VELOCITY (i.e. line-of-sight velocity) of the center of mass of the whole system, and the variable shift resulting from the o...

  8. Lessons Learned From an International, Multisite Simulation Research Study.

    PubMed

    Foronda, Cynthia; Alhusen, Jeanne

    2016-01-01

    The purpose of this article is to describe the process and lessons learned in conducting an international, multisite simulation research study. Key lessons include asking site leaders to complete human subjects training early, applying for a deferral agreement for multiple sites, standardization, seeking consultation, considering differences in simulation centers, and having a back-up plan if committed team members are unable to progress. Although challenging, this process yields many rewards and raises the state of the science to improve pedagogy and student learning outcomes. PMID:26779693

  9. Benzenecarboxylate surface complexation at the goethite (α-FeOOH)/water interface: II. Linking IR spectroscopic observations to mechanistic surface complexation models for phthalate, trimellitate, and pyromellitate

    NASA Astrophysics Data System (ADS)

    Boily, Jean-François; Persson, Per; Sjöberg, Staffan

    2000-10-01

    A study combining information from infrared spectroscopy and adsorption experiments was carried out to investigate phthalate, trimellitate, and pyromellitate complexes at the goethite (α-FeOOH)/water interface. Infrared spectra showed evidence for inner-sphere complexes below pH 6 and outer-sphere complexes in the pH range 3 to 9. Normalized infrared peak areas were used as a semi-quantitative tool to devise diagrams showing the molecular level surface speciation as a function of pH. Surface complexation models that simultaneously predict these diagrams, the proton balance data and the ligand adsorption data were developed with surface complexation theory. Surface complexation modeling was carried out with a Charge Distribution Multisite Complexation Model (CD-MUSIC), assuming goethite particles with surfaces represented by the {110} plane (90% of total particle surface area) and by the {001} plane (10% of total particle surface area). Inner-sphere complexes were described as mononuclear chelates at the {001} plane, whereas outer-sphere complexes were described as binuclear complexes with singly coordinated sites on the {110} plane. The Three-Plane Model (TPM) was used to described surface electrostatics and to distribute the charges of the inner- and the outer-sphere complexes on different planes of adsorption.

  10. Multisite multivariate modeling of daily precipitation and temperature in the Canadian Prairie Provinces using generalized linear models

    NASA Astrophysics Data System (ADS)

    Asong, Zilefac E.; Khaliq, M. N.; Wheater, H. S.

    2016-02-01

    Based on the Generalized Linear Model (GLM) framework, a multisite stochastic modelling approach is developed using daily observations of precipitation and minimum and maximum temperatures from 120 sites located across the Canadian Prairie Provinces: Alberta, Saskatchewan and Manitoba. Temperature is modeled using a two-stage normal-heteroscedastic model by fitting mean and variance components separately. Likewise, precipitation occurrence and conditional precipitation intensity processes are modeled separately. The relationship between precipitation and temperature is accounted for by using transformations of precipitation as covariates to predict temperature fields. Large scale atmospheric covariates from the National Center for Environmental Prediction Reanalysis-I, teleconnection indices, geographical site attributes, and observed precipitation and temperature records are used to calibrate these models for the 1971-2000 period. Validation of the developed models is performed on both pre- and post-calibration period data. Results of the study indicate that the developed models are able to capture spatiotemporal characteristics of observed precipitation and temperature fields, such as inter-site and inter-variable correlation structure, and systematic regional variations present in observed sequences. A number of simulated weather statistics ranging from seasonal means to characteristics of temperature and precipitation extremes and some of the commonly used climate indices are also found to be in close agreement with those derived from observed data. This GLM-based modelling approach will be developed further for multisite statistical downscaling of Global Climate Model outputs to explore climate variability and change in this region of Canada.

  11. Direct spectroscopic observation of singlet oxygen quenching and kinetic studies of physical and chemical singlet oxygen quenching rate constants of synthetic antioxidants (BHA, BHT, and TBHQ) in methanol.

    PubMed

    Lee, Jun Hyun; Jung, Mun Yhung

    2010-08-01

    Singlet oxygen quenching by synthetic antioxidants (BHA, BHT, and TBHQ) was directly observed by spectroscopic monitoring of luminescence at 1268 nm. The luminescence data showed unambiguous evidence of singlet oxygen quenching by synthetic phenolic antioxidants with the highest activity for TBHQ, followed by BHA and BHT. The protective activities of these synthetic antioxidants on alpha-terpinene oxidation with chemically-induced singlet oxygen under dark further confirmed their singlet oxygen quenching abilities. Total singlet oxygen quenching rate constants (k(r) + k(q)) of BHA, BHT, and TBHQ were determined in a system containing alpha-terpinene (as a singlet oxygen trap) and methylene blue (as a sensitizer) during light irradiation, and the values were 5.14 x 10(7), 3.41 x 10(6), and 1.99 x 10(8) M(-1)s(-1), respectively. After the k(r) value of alpha-terpinene was first determined, the k(r) values of the synthetic antioxidants were calculated by measuring their relative reaction rates with singlet oxygen to that of alpha-terpinene under the identical conditions. The k(r) values of the BHA, BHT, and TBHQ were 3.90 x 10(5), 1.23 x 10(5), and 2.93 x 10(6), M(-1)s(-1). The percent partition of chemical quenching over total singlet oxygen quenching (k(r) x 100)/(k(r) + k(q)) for BHA, BHT, and TBHQ were 0.76%, 3.61%, and 1.47%, respectively. The results showed that the synthetic antioxidants quench singlet oxygen almost exclusively through the mechanism of physical quenching. This represents the first report on the singlet oxygen quenching mechanism of these synthetic antioxidants. Practical Application: The synthetic antioxidants, especially TBHQ, have been found to have a strong singlet oxygen quenching ability. This article also clearly showed that singlet oxygen quenching by synthetic antioxidants was mainly by the physical quenching mechanism. The results suggested that these synthetic antioxidants, especially TBHQ, could be used practically for the protection

  12. High-resolution spectroscopic observations of binary stars and yellow stragglers in three open clusters: NGC 2360, NGC 3680, and NGC 5822

    SciTech Connect

    Sales Silva, J. V.; Peña Suárez, V. J.; Katime Santrich, O. J.; Pereira, C. B.; Drake, N. A.; Roig, F. E-mail: jearim@on.br E-mail: claudio@on.br E-mail: froig@on.br

    2014-11-01

    Binary stars in open clusters are very useful targets in constraining the nucleosynthesis process. The luminosities of the stars are known because the distances of the clusters are also known, so chemical peculiarities can be linked directly to the evolutionary status of a star. In addition, binary stars offer the opportunity to verify a relationship between them and the straggler population in both globular and open clusters. We carried out a detailed spectroscopic analysis to derive the atmospheric parameters for 16 red giants in binary systems and the chemical composition of 11 of them in the open clusters NGC 2360, NGC 3680, and NGC 5822. We obtained abundances of C, N, O, Na, Mg, Al, Ca, Si, Ti, Ni, Cr, Y, Zr, La, Ce, and Nd. The atmospheric parameters of the studied stars and their chemical abundances were determined using high-resolution optical spectroscopy. We employ the local thermodynamic equilibrium model atmospheres of Kurucz and the spectral analysis code MOOG. The abundances of the light elements were derived using the spectral synthesis technique. We found that the stars NGC 2360-92 and 96, NGC 3680-34, and NGC 5822-4 and 312 are yellow straggler stars. We show that the spectra of NGC 5822-4 and 312 present evidence of contamination by an A-type star as a secondary star. For the other yellow stragglers, evidence of contamination is given by the broad wings of the Hα. Detection of yellow straggler stars is important because the observed number can be compared with the number predicted by simulations of binary stellar evolution in open clusters. We also found that the other binary stars are not s-process enriched, which may suggest that in these binaries the secondary star is probably a faint main-sequence object. The lack of any s-process enrichment is very useful in setting constraints for the number of white dwarfs in the open cluster, a subject that is related to the birthrate of these kinds of stars in open clusters and also to the age of a

  13. Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System

    PubMed Central

    2016-01-01

    Multisite phosphorylation is a common pathway to regulate protein function, activity, and interaction pattern in vivo, but routine biochemical analysis is often insufficient to identify the number and order of individual phosphorylation reactions and their mechanistic impact on the protein behavior. Here, we integrate complementary mass spectrometry (MS)-based approaches to characterize a multisite phosphorylation-regulated protein system comprising Polo-like kinase 1 (Plk1) and its coactivators Aurora kinase A (Aur-A) and Bora, the interplay of which is essential for mitotic entry after DNA damage-induced cell cycle arrest. Native MS and cross-linking–MS revealed that Aur-A/Bora-mediated Plk1 activation is accompanied by the formation of Aur-A/Bora and Plk1/Bora heterodimers. We found that the Aur-A/Bora interaction is independent of the Bora phosphorylation state, whereas the Plk1/Bora interaction is dependent on extensive Bora multisite phosphorylation. Bottom-up and top-down proteomics analyses showed that Bora multisite phosphorylation proceeds via a well-ordered sequence of site-specific phosphorylation reactions, whereby we could reveal the involvement of up to 16 phosphorylated Bora residues. Ion mobility spectrometry–MS demonstrated that this multisite phosphorylation primes a substantial structural rearrangement of Bora, explaining the interdependence between extensive Bora multisite phosphorylation and Plk1/Bora complex formation. These results represent a first benchmark of our multipronged MS strategy, highlighting its potential to elucidate the mechanistic and structural implications of multisite protein phosphorylation. PMID:27504491

  14. In-Situ Measurements of HCN and CH3CN in the Pacific Troposphere: Sources, Sinks, and Comparisons with Spectroscopic Observations

    NASA Technical Reports Server (NTRS)

    Singh, Hanwant B.; Salas, L.; Herlth, D.; Czech, E.; Viezee, W.; Li, Q.; Jacob, D. J.; Blake, D.; Sachse, G.; Harward, C. N.; Hipskind, R. Stephen (Technical Monitor)

    2002-01-01

    We report the first in-situ measurements of hydrogen cyanide (HCN) and acetonitrile (CH3CN) from the Pacific troposphere (0-12 km) obtained during the NASA/Trace-P mission (Feb.-April, 2001). Mean HCN and CH3CN mixing ratios of 243 (+/-118) ppt and 149 (+/-56) ppt respectively, were measured. The in-situ observations correspond to a total HCN column of 4.4-4.9 x 10(exp 15) molec. cm(exp -2) and a CH3CN column of 2.8-3.0 x 10(exp 15) molec. cm(exp -2). This HCN column is in good agreement with available spectroscopic observations. The atmospheric concentrations of HCN and CH3CN were greatly influenced by outflow of pollution from Asia. There is a linear relationship between the mixing ratios of HCN and CH3CN, and in turn these are well correlated with tracers of biomass combustion (e.g. CH3Cl, CO). Relative enhancements with respect to known tracers of biomass combustion within selected plumes in the free troposphere, and pollution episodes in the boundary layer allow an estimation of a global biomass burning source of 0.8+/-0.4 Tg (N)/y for HCN and 0.4+/-0.1 Tg (N)/y for CH3CN. In comparison, emissions from automobiles and industry are quite small (<0.05 Tg (N)/y). The vertical structure of HCN and CH3CN indicated reduced mixing ratios in the MBL (Marine Boundary Layer). Using, a simple box model, the observed gradients across the top of the MBL are used to derive an oceanic flux of 6.7 x 10(exp -15) g (N) cm(exp -2)/s for HCN and 4.8 x 10(exp -15) g (N) cm(exp -2)/s for CH3CN. An air-sea exchange model is used to conclude that this flux can be maintained if the oceans are under-saturated in HCN and CH3CN by 23% and 17%, respectively. It is inferred that oceanic loss is a dominant sink for these nitrites, and they deposit some 1.3 Tg (N) of nitrogen annually to the oceans. Assuming reaction with OH radicals and loss to the oceans as the major removal processes, a mean atmospheric residence time of 4.7 months for HCN and 5.1 months for CH3CN is calculated. A global

  15. Adsorption of zwitterionic fluoroquinolone antibacterials to goethite: a charge distribution-multisite complexation model.

    PubMed

    Paul, Tias; Liu, Jinyong; Machesky, Michael L; Strathmann, Timothy J

    2014-08-15

    Fluoroquinolone (FQ) antibacterials are aquatic contaminants of emerging concern (CEC), and adsorption to mineral surfaces is expected to play an important role in the fate, transport, and treatment of FQs. This study characterizes and models the adsorption of a zwitterionic FQ, ofloxacin (OFX), to goethite (α-FeOOH) over a wide range of pH (3-11), OFX concentration (20-500 μM), and electrolyte compositions (0.001-0.1M NaCl and NaClO4). Comparing OFX adsorption to structural analogues demonstrates that the carboxylate group is essential for binding to goethite. ATR-FTIR measurements indicate that FQs complex to goethite surfaces through carboxylate and carbonyl oxygen atoms, and that ClO4(-) co-adsorbs with OFX. Adsorption of the zwitterionic OFX increases with increasing ionic strength and is enhanced in NaClO4 relative to NaCl electrolyte, whereas adsorption of a non-zwitterionic analogue is insensitive to ionic strength. A CD-MUSIC (charge distribution-multisite complexation) model, incorporating multiple modes of surface complexation constrained by spectroscopic measurements and the crystallographic distribution of goethite surface sites, yields accurate predictions over wide-ranging solution conditions. According to the model, OFX adsorbs predominantly by inner-sphere complexation on terminal surfaces of the rod-shaped goethite crystals in NaCl electrolyte, and OFX-ClO4(-) ion pairing in NaClO4 induces formation of additional inner- and outer-sphere surface complexes on multiple crystal faces of goethite.

  16. Spectroscopically Unlocking Exoplanet Characteristics

    NASA Astrophysics Data System (ADS)

    Lewis, Nikole

    2016-05-01

    Spectroscopy plays a critical role in a number of areas of exoplanet research. The first exoplanets were detected by precisely measuring Doppler shifts in high resolution (R ~ 100,000) stellar spectra, a technique that has become known as the Radial Velocity (RV) method. The RV method provides critical constraints on exoplanet masses, but is currently limited to some degree by robust line shape predictions. Beyond the RV method, spectroscopy plays a critical role in the characterization of exoplanets beyond their mass and radius. The Hubble Space Telescope has spectroscopically observed the atmospheres of exoplanets that transit their host stars as seen from Earth giving us key insights into atmospheric abundances of key atomic and molecular species as well as cloud optical properties. Similar spectroscopic characterization of exoplanet atmospheres will be carried out at higher resolution (R ~ 100-3000) and with broader wavelength coverage with the James Webb Space Telescope. Future missions such as WFIRST that seek to the pave the way toward the detection and characterization of potentially habitable planets will have the capability of directly measuring the spectra of exoplanet atmospheres and potentially surfaces. Our ability to plan for and interpret spectra from exoplanets relies heavily on the fidelity of the spectroscopic databases available and would greatly benefit from further laboratory and theoretical work aimed at optical properties of atomic, molecular, and cloud/haze species in the pressure and temperature regimes relevant to exoplanet atmospheres.

  17. Spectroscopic pulsational frequency identification and mode determination of γ Doradus star HD 12901

    NASA Astrophysics Data System (ADS)

    Brunsden, E.; Pollard, K. R.; Cottrell, P. L.; Wright, D. J.; De Cat, P.

    2012-12-01

    Using multisite spectroscopic data collected from three sites, the frequencies and pulsational modes of the γ Doradus star HD 12901 were identified. A total of six frequencies in the range 1-2 d-1 were observed, their identifications supported by multiple line-profile measurement techniques and previously published photometry. Five frequencies were of sufficient signal-to-noise ratio for mode identification, and all five displayed similar three-bump standard deviation profiles which were fitted well with (l,m) = (1,1) modes. These fits had reduced χ2 values of less than 18. We propose that this star is an excellent candidate to test models of non-radially pulsating γ Doradus stars as a result of the presence of multiple (1,1) modes. This paper includes data taken at the Mount John University Observatory of the University of Canterbury (New Zealand), the McDonald Observatory of the University of Texas at Austin (Texas, USA) and the European Southern Observatory at La Silla (Chile).

  18. Multi-site identification of a distributed hydrological nitrogen model using Bayesian uncertainty analysis

    NASA Astrophysics Data System (ADS)

    Jiang, Sanyuan; Jomaa, Seifeddine; Büttner, Olaf; Meon, Günter; Rode, Michael

    2015-10-01

    For capturing spatial variations of runoff and nutrient fluxes attributed to catchment heterogeneity, multi-site hydrological water quality monitoring strategies are increasingly put into practice. This study aimed to investigate the impacts of spatially distributed streamflow and streamwater Inorganic Nitrogen (IN) concentration observations on the identification of a continuous time, spatially semi-distributed and process-based hydrological water quality model HYPE (HYdrological Predictions for the Environment). A Bayesian inference based approach DREAM(ZS) (DiffeRential Evolution Adaptive Metrololis algorithm) was combined with HYPE to implement model optimisation and uncertainty analysis on streamflow and streamwater IN concentration simulations at a nested meso scale catchment in central Germany. To this end, a 10-year period (1994-1999 for calibration and 1999-2004 for validation) was utilised. We compared the parameters' posterior distributions, modelling performance using the best estimated parameter set and 95% prediction confidence intervals at catchment outlet for the calibration period that were derived from single-site calibration (SSC) and multi-site calibration (MSC) modes. For SSC, streamflow and streamwater IN concentration observations at only the catchment outlet were used. While, for MSC, streamflow and streamwater IN concentration observations from both catchment outlet and two internal sites were considered. Results showed that the uncertainty intervals of hydrological water quality parameters' posterior distributions estimated from MSC, were narrower than those obtained from SSC. In addition, it was found that the MSC outperformed SSC on streamwater IN concentration simulations at internal sites for both calibration and validation periods, while the influence on streamflow modelling performance was small. This can be explained by the "nested" nature of the catchment and high correlation between discharge observations from different sites

  19. Adaptation to cesarean birth: implementation of an international multisite study.

    PubMed

    Fawcett, Jacqueline; Aber, Cynthia; Weiss, Marianne; Haussler, Susan; Myers, Sheila Taylor; King, Charlette; Newton, Jennifer; Silva, Virginia

    2005-07-01

    The purpose of this column is to describe the implementation of an international multisite Roy adaptation model-based study of women's perceptions of and responses to cesarean birth. The need for the study arose from the concern that women's childbearing needs may not be met to their full satisfaction, especially if the infant is born by cesarean. Serendipity and networking played a part in the selection of four study sites in the United States (Boston, Milwaukee, Norfolk, Oklahoma City) and two in other countries (Finland, Australia). Data were collected by nursing students and staff nurses. Post-hoc consideration of the diversity of study sites revealed opportunities for examination of the influence of the contextual stimuli of culture and geographic region on the women's adaptation to cesarean birth. Strategies used to foster integration of teaching, practice, and research are discussed. PMID:15976041

  20. Ultrasensitivity part II: multisite phosphorylation, stoichiometric inhibitors, and positive feedback.

    PubMed

    Ferrell, James E; Ha, Sang Hoon

    2014-11-01

    In this series of reviews, we are examining ultrasensitive responses, the switch-like input-output relationships that contribute to signal processing in a wide variety of signaling contexts. In the first part of this series, we explored one mechanism for generating ultrasensitivity, zero-order ultrasensitivity, where the saturation of two converting enzymes allows the output to switch from low to high over a tight range of input levels. In this second installment, we focus on three conceptually distinct mechanisms for ultrasensitivity: multisite phosphorylation, stoichiometric inhibitors, and positive feedback. We also examine several related mechanisms and concepts, including cooperativity, reciprocal regulation, coherent feed-forward regulation, and substrate competition, and provide several examples of signaling processes where these mechanisms are known or are suspected to be applicable. PMID:25440716

  1. Four-dimensional multi-site two-photon excitation

    NASA Astrophysics Data System (ADS)

    Daria, Vincent R.; Stricker, Christian; Bowman, Richard; Bachor, Hans-A.; Redman, Stephen

    2010-02-01

    We use the holographic method to project an arbitrary array of diffraction-limited focal spots suitable for multi-site twophoton excitation. The spot array can be projected arbitrarily within a three-dimensional (3D) volume, while the fourth dimension in time is attributed to high temporal resolution via high-speed non-iterative calculation of the hologram using a video graphics accelerator board. We show that the spots have sufficient energy and spatiotemporal photon density for localized two-photon excitation at individual spots in the array. The significance of this work points to 3D microscopy, non-linear micro-fabrication, volume holographic optical storage and biomedical instrumentation. In neuroscience, timecritical release of neurotransmitters at multiple sites within complex dendritic trees of neurons can lead to insights on the mechanisms of information processing in the brain.

  2. Multi-site Phosphorylation Regulates Bim Stability and Apoptotic Activity

    PubMed Central

    Hübner, Anette; Barrett, Tamera; Flavell, Richard A.; Davis, Roger J.

    2008-01-01

    The pro-apoptotic BH3-only protein Bim is established to be an important mediator of signaling pathways that induce cell death. Multi-site phosphorylation of Bim by several members of the MAP kinase group is implicated as a regulatory mechanism that controls the apoptotic activity of Bim. To test the role of Bim phosphorylation in vivo, we constructed mice with a series of mutant alleles that express phosphorylation-defective Bim proteins. We show that mutation of the phosphorylation site Thr-112 causes decreased binding of Bim to the anti-apoptotic protein Bcl2 and can increase cell survival. In contrast, mutation of the phosphorylation sites Ser-55, Ser-65, and Ser-73 can cause increased apoptosis because of reduced proteasomal degradation of Bim. Together, these data indicate that phosphorylation can regulate Bim by multiple mechanisms and that the phosphorylation of Bim on different sites can contribute to the sensitivity of cellular apoptotic responses. PMID:18498746

  3. Power estimation for non-standardized multisite studies.

    PubMed

    Keshavan, Anisha; Paul, Friedemann; Beyer, Mona K; Zhu, Alyssa H; Papinutto, Nico; Shinohara, Russell T; Stern, William; Amann, Michael; Bakshi, Rohit; Bischof, Antje; Carriero, Alessandro; Comabella, Manuel; Crane, Jason C; D'Alfonso, Sandra; Demaerel, Philippe; Dubois, Benedicte; Filippi, Massimo; Fleischer, Vinzenz; Fontaine, Bertrand; Gaetano, Laura; Goris, An; Graetz, Christiane; Gröger, Adriane; Groppa, Sergiu; Hafler, David A; Harbo, Hanne F; Hemmer, Bernhard; Jordan, Kesshi; Kappos, Ludwig; Kirkish, Gina; Llufriu, Sara; Magon, Stefano; Martinelli-Boneschi, Filippo; McCauley, Jacob L; Montalban, Xavier; Mühlau, Mark; Pelletier, Daniel; Pattany, Pradip M; Pericak-Vance, Margaret; Cournu-Rebeix, Isabelle; Rocca, Maria A; Rovira, Alex; Schlaeger, Regina; Saiz, Albert; Sprenger, Till; Stecco, Alessandro; Uitdehaag, Bernard M J; Villoslada, Pablo; Wattjes, Mike P; Weiner, Howard; Wuerfel, Jens; Zimmer, Claus; Zipp, Frauke; Hauser, Stephen L; Oksenberg, Jorge R; Henry, Roland G

    2016-07-01

    A concern for researchers planning multisite studies is that scanner and T1-weighted sequence-related biases on regional volumes could overshadow true effects, especially for studies with a heterogeneous set of scanners and sequences. Current approaches attempt to harmonize data by standardizing hardware, pulse sequences, and protocols, or by calibrating across sites using phantom-based corrections to ensure the same raw image intensities. We propose to avoid harmonization and phantom-based correction entirely. We hypothesized that the bias of estimated regional volumes is scaled between sites due to the contrast and gradient distortion differences between scanners and sequences. Given this assumption, we provide a new statistical framework and derive a power equation to define inclusion criteria for a set of sites based on the variability of their scaling factors. We estimated the scaling factors of 20 scanners with heterogeneous hardware and sequence parameters by scanning a single set of 12 subjects at sites across the United States and Europe. Regional volumes and their scaling factors were estimated for each site using Freesurfer's segmentation algorithm and ordinary least squares, respectively. The scaling factors were validated by comparing the theoretical and simulated power curves, performing a leave-one-out calibration of regional volumes, and evaluating the absolute agreement of all regional volumes between sites before and after calibration. Using our derived power equation, we were able to define the conditions under which harmonization is not necessary to achieve 80% power. This approach can inform choice of processing pipelines and outcome metrics for multisite studies based on scaling factor variability across sites, enabling collaboration between clinical and research institutions. PMID:27039700

  4. Power estimation for non-standardized multisite studies.

    PubMed

    Keshavan, Anisha; Paul, Friedemann; Beyer, Mona K; Zhu, Alyssa H; Papinutto, Nico; Shinohara, Russell T; Stern, William; Amann, Michael; Bakshi, Rohit; Bischof, Antje; Carriero, Alessandro; Comabella, Manuel; Crane, Jason C; D'Alfonso, Sandra; Demaerel, Philippe; Dubois, Benedicte; Filippi, Massimo; Fleischer, Vinzenz; Fontaine, Bertrand; Gaetano, Laura; Goris, An; Graetz, Christiane; Gröger, Adriane; Groppa, Sergiu; Hafler, David A; Harbo, Hanne F; Hemmer, Bernhard; Jordan, Kesshi; Kappos, Ludwig; Kirkish, Gina; Llufriu, Sara; Magon, Stefano; Martinelli-Boneschi, Filippo; McCauley, Jacob L; Montalban, Xavier; Mühlau, Mark; Pelletier, Daniel; Pattany, Pradip M; Pericak-Vance, Margaret; Cournu-Rebeix, Isabelle; Rocca, Maria A; Rovira, Alex; Schlaeger, Regina; Saiz, Albert; Sprenger, Till; Stecco, Alessandro; Uitdehaag, Bernard M J; Villoslada, Pablo; Wattjes, Mike P; Weiner, Howard; Wuerfel, Jens; Zimmer, Claus; Zipp, Frauke; Hauser, Stephen L; Oksenberg, Jorge R; Henry, Roland G

    2016-07-01

    A concern for researchers planning multisite studies is that scanner and T1-weighted sequence-related biases on regional volumes could overshadow true effects, especially for studies with a heterogeneous set of scanners and sequences. Current approaches attempt to harmonize data by standardizing hardware, pulse sequences, and protocols, or by calibrating across sites using phantom-based corrections to ensure the same raw image intensities. We propose to avoid harmonization and phantom-based correction entirely. We hypothesized that the bias of estimated regional volumes is scaled between sites due to the contrast and gradient distortion differences between scanners and sequences. Given this assumption, we provide a new statistical framework and derive a power equation to define inclusion criteria for a set of sites based on the variability of their scaling factors. We estimated the scaling factors of 20 scanners with heterogeneous hardware and sequence parameters by scanning a single set of 12 subjects at sites across the United States and Europe. Regional volumes and their scaling factors were estimated for each site using Freesurfer's segmentation algorithm and ordinary least squares, respectively. The scaling factors were validated by comparing the theoretical and simulated power curves, performing a leave-one-out calibration of regional volumes, and evaluating the absolute agreement of all regional volumes between sites before and after calibration. Using our derived power equation, we were able to define the conditions under which harmonization is not necessary to achieve 80% power. This approach can inform choice of processing pipelines and outcome metrics for multisite studies based on scaling factor variability across sites, enabling collaboration between clinical and research institutions.

  5. Exploiting Multisite Gateway and pENFRUIT plasmid collection for fruit genetic engineering.

    PubMed

    Estornell, Leandro H; Granell, Antonio; Orzaez, Diego

    2012-01-01

    MultiSite Gateway cloning techniques based on homologous recombination facilitate the combinatorial assembly of basic genetic pieces (i.e., promoters, CDS, and terminators) into gene expression or gene silencing cassettes. pENFRUIT is a collection of MultiSite Triple Gateway Entry vectors dedicated to genetic engineering in fruits. It comprises a number of fruit-operating promoters as well as C-terminal tags adapted to the Gateway standard. In this way, flanking regulatory/labeling sequences can be easily Gateway-assembled with a given gene of interest for its ectopic expression or silencing in fruits. The resulting gene constructs can be analyzed in stable transgenic plants or in transient expression assays, the latter allowing fast testing of the increasing number of combinations arising from MultiSite methodology. A detailed description of the use of MultiSite cloning methodology for the assembly of pENFRUIT elements is presented. PMID:22351021

  6. The relationship between involvement in and use of evaluation in multi-site evaluations.

    PubMed

    Roseland, Denise; Lawrenz, Frances; Thao, Mao

    2015-02-01

    This research explores the relationship between participation in evaluation and the use of evaluation findings and processes within three large-scale multi-site evaluations. Using canonical correlation analysis and a collection of 20 interviews, this study describes and tests the relationship between these two critical conceptual powerhouses in evaluation. Using data that were collected as a part of the NSF-funded research Beyond Evaluation Use (Lawrenz & King, 2009), this study found that some theories and beliefs about participatory evaluation contribute to use and influence in similar ways as in single-site evaluations. The differences identified in this research highlight potential planning and implementation considerations that might allow multi-site evaluators and funders of multi-site evaluation to enhance use and influence of multi-site evaluations.

  7. High-Accuracy Quartic Force Field Calculations for the Spectroscopic Constants and Vibrational Frequencies of 1(exp 1)A' l-C3H(-): A Possible Link to Lines Observed in the Horsehead Nebula PDR

    NASA Technical Reports Server (NTRS)

    Fortenberry, Ryan C.; Huang, Xinchuan; Crawford, T. Daniel; Lee, Timothy J.

    2013-01-01

    It has been shown that rotational lines observed in the Horsehead nebula photon-dominated-region (PDR) are probably not caused by l-C3H+, as was originally suggested. In the search for viable alternative candidate carriers, quartic force fields are employed here to provide highly accurate rotational constants, as well as fundamental vibrational frequencies, for another candidate carrier: 1 (sup 1)A' C3H(-). The ab initio computed spectroscopic constants provided in this work are, compared to those necessary to define the observed lines, as accurate as the computed spectroscopic constants for many of the known interstellar anions. Additionally, the computed D-eff for C3H(-) is three times closer to the D deduced from the observed Horsehead nebula lines relative to l-C3H(+). As a result, 1 (sup 1)A' C3H(-). is a more viable candidate for these observed rotational transitions and would be the seventh confirmed interstellar anion detected within the past decade and the first C(sub n)H(-) molecular anion with an odd n.

  8. Increasing the ranks of academic researchers in mental health: a multisite approach to postdoctoral fellowship training.

    PubMed

    O'Hara, Ruth; Cassidy-Eagle, Erin L; Beaudreau, Sherry A; Eyler, Lisa T; Gray, Heather L; Giese-Davis, Janine; Hubbard, Jeffrey; Yesavage, Jerome A

    2010-01-01

    This report highlights the use of multisite training for psychiatry and psychology postdoctoral fellows developing careers in academic clinical research in the field of mental health. The objective is to describe a model of training for young investigators to establish independent academic clinical research careers, including (1) program structure and eligibility, (2) program goals and development of a multisite curriculum, (3) use of technology for implementing the program across multiple sites, and (4) advantages and challenges of this multisite approach. In 2000, in collaboration with the Veterans Affairs (VA) Mental Illness Research, Education and Clinical Centers (MIRECCs), the VA Office of Academic Affiliations launched the Special Fellowship Program in Advanced Psychiatry and Psychology. Each of the 10 currently participating VA sites across the United States is affiliated with a MIRECC and an academic medical institution. In the first five years of this fellowship program, 83 fellows (34 psychiatrists and 49 psychologists) have participated. The success of this multisite approach is evidenced by the 58 fellows who have already graduated from the program: 70% have entered academic clinical research positions, and over 25 have obtained independent extramural grant support from the VA or the National Institutes of Health. Multisite training results in a greater transfer of knowledge and capitalizes on the nationwide availability of experts, creating unique networking and learning opportunities for trainees. The VA's multisite fellowship program plays a valuable role in preparing substantial numbers of psychiatry and psychology trainees for a range of academic clinical research and leadership positions in the field of mental health.

  9. The value and potential of multisited ethnography for science education research: a review of Jrène Rahm's Science in the Making at the Margin

    NASA Astrophysics Data System (ADS)

    Beeman-Cadwallader, Nicole

    2012-03-01

    Rahm sought to illuminate how children and youth make meaning of science in three out-of-school time programs, and the identity work that is done through the trajectory of their youth toward their young adulthood. Through using multisited ethnography, she asserts that we can learn more about what the youth say about their science learning and science literacy development in these programs. She has revealed through her rich data the potential value of multisited ethnography for science education research. A similar theme of insider/outsider status to science emerged in each of the three sites. The nature of the data collected in Rahm's multisited ethnography allowed for the unveiling of the similarities in this theme, but also made evident the nuanced ways that this theme presented itself differently across the three sites. The additional potential came through in the varied data Rahm could have delved into and did not. A unique characteristic of ethnographic research, that is not necessarily present in other research methods, is that a wide array of varied data is collected. An analysis of documents, images, and observational field notes, which go beyond interview data, may provide deeper understandings previously untouched in science education.

  10. A DVD Spectroscope: A Simple, High-Resolution Classroom Spectroscope

    ERIC Educational Resources Information Center

    Wakabayashi, Fumitaka; Hamada, Kiyohito

    2006-01-01

    Digital versatile disks (DVDs) have successfully made up an inexpensive but high-resolution spectroscope suitable for classroom experiments that can easily be made with common material and gives clear and fine spectra of various light sources and colored material. The observed spectra can be photographed with a digital camera, and such images can…

  11. Spectroscopic survey of LAMOST

    NASA Astrophysics Data System (ADS)

    Zhao, Yongheng

    2014-07-01

    LAMOST is a special reflecting Schmidt telescope. LAMOST breaks through the bottleneck of the large scale spectroscopic survey observation with both large aperture (effective aperture of 3.6 - 4.9m) and wide field of view (5 degrees). It is an innovative active reflecting Schmidt configuration achieved by changing mirror surface continuously to achieve a series different reflecting Schmidt system in different moments. By using the parallel controllable fiber positioning technique, the focal surface of 1.75 meters in diameter accommodates 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST is the telescope of the highest spectrum acquiring rate. As a national large scientific project, LAMOST project was proposed formally in 1996. The construction was started in 2001 and completed in 2008. After commission period, LAMOST pilot survey was started in October 2011 and spectroscopic survey began in September 2012. From October 2011 to June 2013, LAMOST has obtained more than 2 million spectra of celestial objects. There are 1.7 million spectra of stars, in which the stellar parameters (effective temperature, surface gravity, metalicitiy and radial velocity) of more than 1 million stars was obtained. In the first period of spectroscopic survey of LAMOST, 5 million of stellar spectra will be obtained and will make substantial contribution to the study of the stellar astrophysics and the structure of the Galaxy, such as the spheroid substructure of the Galaxy, the galactic gravitational potential and the distribution of the dark matter in the Galaxy, the extremely metal poor stars and hypervelocity stars, the 3D extinction in the Galaxy, the structure of thin and thick disks of the Galaxy, and so on.

  12. Construction and probing of multisite chiral catalysts: dendrimer fixation of c2-symmetrical diphosphinerhodium complexes.

    PubMed

    Engel, Gerald D; Gade, Lutz H

    2002-09-16

    A series of chiral phosphine-functionalized poly(propyleneimine) (PPI) dendrimers was synthesized by the reaction of carboxyl-linked C(2)-chiral pyrphos ligand (pyrphos=3,4-bis(diphenylphosphino)pyrrolidine) with zeroth-fourth generation PPI using ethyl-N,N-dimethylaminopropylcarbodiimide (EDC)/1-hydroxybenzotriazol as a coupling reagent. The dendrimers obtained were characterized by NMR spectroscopy and elemental analysis as well as FAB and MALDI-TOF mass spectrometry, which established their molecular masses of up to 20 700 amu. Metalation of the multi-site phosphines with [Rh(COD)(2)]BF(4) cleanly yielded the cationic rhododendrimers containing up to 32 metal centers (for the fourth generation species), representing the largest chiral phosphine dendrimer catalyst studied to date. The complete metalation of the chiral phosphine sites was demonstrated by (31)P NMR spectroscopy and the observation of the coordination-shifted AB part of the ABX spin system (delta(A)=33.9, delta(B)=32.9; (1)J(Rh,P)=150, 153 Hz; (2)J(P,P)=28 Hz). The relationship between the size/generation of the dendrimer and its catalytic properties was established in the asymmetric hydrogenation of Z-methyl-alpha-acetamidocinammate and dimethyl itaconate. A decrease in both activity and selectivity of the dendrimer catalysts was observed on going to the higher generations. PMID:12298024

  13. Spectroscopic survey of LAMOST

    NASA Astrophysics Data System (ADS)

    Zhao, Yongheng

    2015-08-01

    LAMOST is a special reflecting Schmidt telescope. LAMOST breaks through the bottleneck of the large scale spectroscopic survey observation with both large aperture (effective aperture of 3.6 - 4.9m) and wide field of view (5 degrees). It is an innovative active reflecting Schmidt configuration achieved by changing mirror surface continuously to achieve a series different reflecting Schmidt system in different moments. By using the parallel controllable fiber positioning technique, the focal surface of 1.75 meters in diameter accommodates 4000 optical fibers. Also, LAMOST has 16 spectrographs with 32 CCD cameras. LAMOST is the telescope of the highest spectrum acquiring rate.In the spectroscopic survey of LAMOST from October 2011 to June 2014, LAMOST has obtained more than 4.13 million spectra of celestial objects. There are 3.27 million spectra of stars, in which the stellar parameters of 2.16 million stars were obtained.In the five-year regular survey upto 2017, LAMOST will obtaine 5 million stellar spectra, which would make substantial contribution to the study of the stellar astrophysics and the structure of the Galaxy, such as the spheroid substructure of the Galaxy, the galactic gravitational potential and the distribution of the dark matter in the Galaxy, the extremely metal poor stars and hypervelocity stars, the 3D extinction in the Galaxy, the structure of thin and thick disks of the Galaxy, and so on.

  14. Four-dimensional multi-site photolysis of caged neurotransmitters.

    PubMed

    Go, Mary Ann; To, Minh-Son; Stricker, Christian; Redman, Stephen; Bachor, Hans-A; Stuart, Greg J; Daria, Vincent R

    2013-01-01

    Neurons receive thousands of synaptic inputs that are distributed in space and time. The systematic study of how neurons process these inputs requires a technique to stimulate multiple yet highly targeted points of interest along the neuron's dendritic tree. Three-dimensional multi-focal patterns produced via holographic projection combined with two-photon photolysis of caged compounds can provide for highly localized release of neurotransmitters within each diffraction-limited focus, and in this way emulate simultaneous synaptic inputs to the neuron. However, this technique so far cannot achieve time-dependent stimulation patterns due to fundamental limitations of the hologram-encoding device and other factors that affect the consistency of controlled synaptic stimulation. Here, we report an advanced technique that enables the design and application of arbitrary spatio-temporal photostimulation patterns that resemble physiological synaptic inputs. By combining holographic projection with a programmable high-speed light-switching array, we have overcome temporal limitations with holographic projection, allowing us to mimic distributed activation of synaptic inputs leading to action potential generation. Our experiments uniquely demonstrate multi-site two-photon glutamate uncaging in three dimensions with submillisecond temporal resolution. Implementing this approach opens up new prospects for studying neuronal synaptic integration in four dimensions. PMID:24348330

  15. Four-dimensional multi-site photolysis of caged neurotransmitters

    PubMed Central

    Go, Mary Ann; To, Minh-Son; Stricker, Christian; Redman, Stephen; Bachor, Hans-A.; Stuart, Greg J.; Daria, Vincent R.

    2013-01-01

    Neurons receive thousands of synaptic inputs that are distributed in space and time. The systematic study of how neurons process these inputs requires a technique to stimulate multiple yet highly targeted points of interest along the neuron's dendritic tree. Three-dimensional multi-focal patterns produced via holographic projection combined with two-photon photolysis of caged compounds can provide for highly localized release of neurotransmitters within each diffraction-limited focus, and in this way emulate simultaneous synaptic inputs to the neuron. However, this technique so far cannot achieve time-dependent stimulation patterns due to fundamental limitations of the hologram-encoding device and other factors that affect the consistency of controlled synaptic stimulation. Here, we report an advanced technique that enables the design and application of arbitrary spatio-temporal photostimulation patterns that resemble physiological synaptic inputs. By combining holographic projection with a programmable high-speed light-switching array, we have overcome temporal limitations with holographic projection, allowing us to mimic distributed activation of synaptic inputs leading to action potential generation. Our experiments uniquely demonstrate multi-site two-photon glutamate uncaging in three dimensions with submillisecond temporal resolution. Implementing this approach opens up new prospects for studying neuronal synaptic integration in four dimensions. PMID:24348330

  16. Implementing nutrition diagnosis at a multisite health care organization.

    PubMed

    Van Heukelom, Holly; Fraser, Valli; Koh, Jiak-Chin; McQueen, Kay; Vogt, Kara; Johnson, Frances

    2011-01-01

    The American Dietetic Association Nutrition Care Process (NCP) is designed to improve patient care and interdisciplinary communication through the consistent use of standardized nutrition language. Supported by Dietitians of Canada, the NCP has been gaining prominence across Canada. In spring 2009, registered dietitians at Providence Health Care, an academic, multisite health care organization in Vancouver, British Columbia, began using the NCP with a focus on nutrition diagnosis. The success of nutrition diagnosis at Providence Health Care has depended on support from the Clinical Nutrition Department leadership, commitment from the NCP champions, regularly scheduled lunch-and-learn sessions, revised nutrition assessment forms with a section for nutrition diagnosis statements, and the Pocket Guide for International Dietetics & Nutrition Terminology (IDNT) Reference Manual. Audit results from June through August 2010 showed a 92% nutrition diagnosis completion rate for acute-care and long-term care sites within Providence Health Care. Ongoing audits will be used to evaluate the accuracy and quality of nutrition diagnosis statements. This evaluation will allow Providence Health Care dietitians to move forward with nutrition intervention.

  17. Spectroscopic Classifications of Optical Transients with SOAR

    NASA Astrophysics Data System (ADS)

    Hounsell, R. A.; Miller, J. A.; Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.; Smith, K. W.; Wright, D.; Smartt, S. J.; Huber, M.; Chambers, K. C.; Flewelling, H.; Willman, M.; Primak, N.; Schultz, A.; Gibson, B.; Magnier, E.; Waters, C.; Tonry, J.; Wainscoat, R. J.

    2016-06-01

    We report the following classifications of optical transients from spectroscopic observations with the Goodman spectrograph on the SOAR 4-m telescope. Targets were supplied by the Pan-STARRS Survey for Transients (PSST).

  18. THE BOLOCAM GALACTIC PLANE SURVEY. X. A COMPLETE SPECTROSCOPIC CATALOG OF DENSE MOLECULAR GAS OBSERVED TOWARD 1.1 mm DUST CONTINUUM SOURCES WITH 7.°5 ≤ l ≤ 194°

    SciTech Connect

    Shirley, Yancy L.; Svoboda, Brian; Ellsworth-Bowers, Timothy P.; Schlingman, Wayne M.; Ginsburg, Adam; Battersby, Cara; Stringfellow, Guy; Glenn, Jason; Bally, John; Rosolowsky, Erik; Gerner, Thomas; Mairs, Steven; Dunham, Miranda K.

    2013-11-01

    The Bolocam Galactic Plane Survey (BGPS) is a 1.1 mm continuum survey of dense clumps of dust throughout the Galaxy covering 170 deg{sup 2}. We present spectroscopic observations using the Heinrich Hertz Submillimeter Telescope of the dense gas tracers, HCO{sup +} and N{sub 2}H{sup +} 3-2, for all 6194 sources in the BGPS v1.0.1 catalog between 7.°5 ≤ l ≤ 194°. This is the largest targeted spectroscopic survey of dense molecular gas in the Milky Way to date. We find unique velocities for 3126 (50.5%) of the BGPS v1.0.1 sources observed. Strong N{sub 2}H{sup +} 3-2 emission (T {sub mb} > 0.5 K) without HCO{sup +} 3-2 emission does not occur in this catalog. We characterize the properties of the dense molecular gas emission toward the entire sample. HCO{sup +} is very sub-thermally populated and the 3-2 transitions are optically thick toward most BGPS clumps. The median observed line width is 3.3 km s{sup –1} consistent with supersonic turbulence within BGPS clumps. We find strong correlations between dense molecular gas integrated intensities and 1.1 mm peak flux and the gas kinetic temperature derived from previously published NH{sub 3} observations. These intensity correlations are driven by the sensitivity of the 3-2 transitions to excitation conditions rather than by variations in molecular column density or abundance. We identify a subset of 113 sources with stronger N{sub 2}H{sup +} than HCO{sup +} integrated intensity, but we find no correlations between the N{sub 2}H{sup +}/HCO{sup +} ratio and 1.1 mm continuum flux density, gas kinetic temperature, or line width. Self-absorbed profiles are rare (1.3%)

  19. HIGH-ACCURACY QUARTIC FORCE FIELD CALCULATIONS FOR THE SPECTROSCOPIC CONSTANTS AND VIBRATIONAL FREQUENCIES OF 1{sup 1} A' l-C{sub 3}H{sup -}: A POSSIBLE LINK TO LINES OBSERVED IN THE HORSEHEAD NEBULA PHOTODISSOCIATION REGION

    SciTech Connect

    Fortenberry, Ryan C.; Lee, Timothy J.; Huang, Xinchuan; Crawford, T. Daniel

    2013-07-20

    It has been shown that rotational lines observed in the Horsehead nebula photodissociation region (PDR) are probably not caused by l-C{sub 3}H{sup +}, as was originally suggested. In the search for viable alternative candidate carriers, quartic force fields are employed here to provide highly accurate rotational constants, as well as fundamental vibrational frequencies, for another candidate carrier: 1 {sup 1} A' C{sub 3}H{sup -}. The ab initio computed spectroscopic constants provided in this work are, compared to those necessary to define the observed lines, as accurate as the computed spectroscopic constants for many of the known interstellar anions. Additionally, the computed D{sub eff} for C{sub 3}H{sup -} is three times closer to the D deduced from the observed Horsehead nebula lines relative to l-C{sub 3}H{sup +}. As a result, 1 {sup 1} A' C{sub 3}H{sup -} is a more viable candidate for these observed rotational transitions. It has been previously proposed that at least C{sub 6}H{sup -} may be present in the Horsehead nebular PDR formed by way of radiative attachment through its dipole-bound excited state. C{sub 3}H{sup -} could form in a similar way through its dipole-bound state, but its valence excited state increases the number of relaxation pathways possible to reach the ground electronic state. In turn, the rate of formation for C{sub 3}H{sup -} could be greater than the rate of its destruction. C{sub 3}H{sup -} would be the seventh confirmed interstellar anion detected within the past decade and the first C{sub n}H{sup -} molecular anion with an odd n.

  20. The Bolocam Galactic Plane Survey. X. A Complete Spectroscopic Catalog of Dense Molecular Gas Observed toward 1.1 mm Dust Continuum Sources with 7.°5 <= l <= 194°

    NASA Astrophysics Data System (ADS)

    Shirley, Yancy L.; Ellsworth-Bowers, Timothy P.; Svoboda, Brian; Schlingman, Wayne M.; Ginsburg, Adam; Rosolowsky, Erik; Gerner, Thomas; Mairs, Steven; Battersby, Cara; Stringfellow, Guy; Dunham, Miranda K.; Glenn, Jason; Bally, John

    2013-11-01

    The Bolocam Galactic Plane Survey (BGPS) is a 1.1 mm continuum survey of dense clumps of dust throughout the Galaxy covering 170 deg2. We present spectroscopic observations using the Heinrich Hertz Submillimeter Telescope of the dense gas tracers, HCO+ and N2H+ 3-2, for all 6194 sources in the BGPS v1.0.1 catalog between 7.°5 <= l <= 194°. This is the largest targeted spectroscopic survey of dense molecular gas in the Milky Way to date. We find unique velocities for 3126 (50.5%) of the BGPS v1.0.1 sources observed. Strong N2H+ 3-2 emission (T mb > 0.5 K) without HCO+ 3-2 emission does not occur in this catalog. We characterize the properties of the dense molecular gas emission toward the entire sample. HCO+ is very sub-thermally populated and the 3-2 transitions are optically thick toward most BGPS clumps. The median observed line width is 3.3 km s-1 consistent with supersonic turbulence within BGPS clumps. We find strong correlations between dense molecular gas integrated intensities and 1.1 mm peak flux and the gas kinetic temperature derived from previously published NH3 observations. These intensity correlations are driven by the sensitivity of the 3-2 transitions to excitation conditions rather than by variations in molecular column density or abundance. We identify a subset of 113 sources with stronger N2H+ than HCO+ integrated intensity, but we find no correlations between the N2H+/HCO+ ratio and 1.1 mm continuum flux density, gas kinetic temperature, or line width. Self-absorbed profiles are rare (1.3%).

  1. Coping Skills Among Adolescent Suicide Attempters: Results of a Multisite Study

    PubMed Central

    Mirkovic, Bojan; Labelle, Réal; Guilé, Jean-Marc; Belloncle, Vincent; Bodeau, Nicolas; Knafo, Alexandra; Condat, Agnès; Bapt-Cazalets, Nathalie; Marguet, Christophe; Breton, Jean-Jacques; Cohen, David; Gérardin, Priscille

    2015-01-01

    Objectives: A multisite study was undertaken to advance our understanding of how coping skills, depression, and suicidal ideation are related among adolescents who attempt suicide. Two hypotheses were postulated: productive coping and nonproductive coping would be associated, respectively, with lower and higher depression scores when age, sex, and stressful life events (SLEs) were controlled; and productive coping and nonproductive coping would be associated, respectively, with the presence and absence of suicidal ideation when age, sex, and SLEs were controlled. Methods: Participants were 167 adolescents (13 to 17 years of age) hospitalized for attempting suicide in 5 pediatric departments across France. Four instruments were administered: the Kiddie Schedule for Affective Disorders and Schizophrenia—Present and Lifetime Version, the Adolescent Coping Scale, the Life Events Questionnaire, and the Columbia-Suicide Severity Rating Scale. Descriptive analyses and univariate and multiple regression models were completed. Results: Both hypotheses were confirmed. Focus on the positive emerged as a significant variable in both models; depression emerged as a significant variable in the suicidal ideation model. The only sex difference observed was that girls made greater use of wishful thinking and seek social support. Conclusions: These findings suggest that coping skills are important mechanisms through which depression and suicidal ideation are maintained after attempting suicide. In intervening with adolescents who have attempted suicide, it may be useful to emphasize cognitive work geared to looking on the bright side, positive thinking, and fighting depression. PMID:25886670

  2. Multisite, multimodal neuroimaging of chronic urological pelvic pain: Methodology of the MAPP Research Network.

    PubMed

    Alger, Jeffry R; Ellingson, Benjamin M; Ashe-McNalley, Cody; Woodworth, Davis C; Labus, Jennifer S; Farmer, Melissa; Huang, Lejian; Apkarian, A Vania; Johnson, Kevin A; Mackey, Sean C; Ness, Timothy J; Deutsch, Georg; Harris, Richard E; Clauw, Daniel J; Glover, Gary H; Parrish, Todd B; Hollander, Jan den; Kusek, John W; Mullins, Chris; Mayer, Emeran A

    2016-01-01

    The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network is an ongoing multi-center collaborative research group established to conduct integrated studies in participants with urologic chronic pelvic pain syndrome (UCPPS). The goal of these investigations is to provide new insights into the etiology, natural history, clinical, demographic and behavioral characteristics, search for new and evaluate candidate biomarkers, systematically test for contributions of infectious agents to symptoms, and conduct animal studies to understand underlying mechanisms for UCPPS. Study participants were enrolled in a one-year observational study and evaluated through a multisite, collaborative neuroimaging study to evaluate the association between UCPPS and brain structure and function. 3D T1-weighted structural images, resting-state fMRI, and high angular resolution diffusion MRI were acquired in five participating MAPP Network sites using 8 separate MRI hardware and software configurations. We describe the neuroimaging methods and procedures used to scan participants, the challenges encountered in obtaining data from multiple sites with different equipment/software, and our efforts to minimize site-to-site variation. PMID:27408791

  3. Multisite, multimodal neuroimaging of chronic urological pelvic pain: Methodology of the MAPP Research Network.

    PubMed

    Alger, Jeffry R; Ellingson, Benjamin M; Ashe-McNalley, Cody; Woodworth, Davis C; Labus, Jennifer S; Farmer, Melissa; Huang, Lejian; Apkarian, A Vania; Johnson, Kevin A; Mackey, Sean C; Ness, Timothy J; Deutsch, Georg; Harris, Richard E; Clauw, Daniel J; Glover, Gary H; Parrish, Todd B; Hollander, Jan den; Kusek, John W; Mullins, Chris; Mayer, Emeran A

    2016-01-01

    The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network is an ongoing multi-center collaborative research group established to conduct integrated studies in participants with urologic chronic pelvic pain syndrome (UCPPS). The goal of these investigations is to provide new insights into the etiology, natural history, clinical, demographic and behavioral characteristics, search for new and evaluate candidate biomarkers, systematically test for contributions of infectious agents to symptoms, and conduct animal studies to understand underlying mechanisms for UCPPS. Study participants were enrolled in a one-year observational study and evaluated through a multisite, collaborative neuroimaging study to evaluate the association between UCPPS and brain structure and function. 3D T1-weighted structural images, resting-state fMRI, and high angular resolution diffusion MRI were acquired in five participating MAPP Network sites using 8 separate MRI hardware and software configurations. We describe the neuroimaging methods and procedures used to scan participants, the challenges encountered in obtaining data from multiple sites with different equipment/software, and our efforts to minimize site-to-site variation.

  4. Multi-site telemammography system: preliminary assessment of technical and operational issues

    NASA Astrophysics Data System (ADS)

    Drescher, John M.; Maitz, Glenn S.; Traylor, Christopher; Leader, J. Ken; Clearfield, Ronald J.; Shah, Ratan; Ganott, Marie A.; Pugliese, Francine; Duffner, Dian; Lockhart, Janet; Gur, David

    2003-05-01

    Our goal was to develop an inexpensive, high-quality, multi-site telemammography system, implemented with low-level data connections that provided a communication link for an "almost real-time" response from a radiologist (central site) to remote "underserved" sites. The remote sites digitize mammographic films using high-resolution, laser digitizers. Images are automatically cropped, compressed (wavelet-based), and encrypted prior to transmission. At the central site images are decrypted, decompressed, unsharp masked, and displayed using automatically determined LUTs. The sites communicate instantly via a "chat box." Remote sites 1, 2, and 3 are 15, 20, and 90 miles from the central site, respectively, and connected by POTS (sites 1 and 2) and LAN (site 3). Only minimal noticeable difference at compression levels of 50:1 and 75:1 could be identified unless magnified to extreme levels. Two experienced observers rated the LUTs for 200 images as "acceptable" to "excellent." Average cycle times to digitize, transmit and receive cases (four films each) at 75:1 compression were 5.97, 6.85, and 5.77 min/case from sites 1, 2, and 3, respectively. Unique data-handling schemes significantly decrease the image file size and allow successful transmission in a reliable, timely manner. Over 1000 cases have been transmitted to date. Messaging was found to be easy to use.

  5. Report From the Working Group Conference on Multisite Trial Design for Cognitive Remediation in Schizophrenia

    PubMed Central

    Keefe, Richard S. E.; Vinogradov, Sophia; Medalia, Alice; Silverstein, Steven M.; Bell, Morris D.; Dickinson, Dwight; Ventura, Joseph; Marder, Stephen R.; Stroup, T. Scott

    2011-01-01

    The National Institute of Mental Health (NIMH)-Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) Project and related efforts have stimulated the initiation of several studies of pharmacologic treatments for cognitive impairment in schizophrenia. Cognitive remediation may provide an excellent platform for the provision of new learning opportunities and the acquisition of new skills for patients who are engaged in pharmacologic trials to improve cognition. However, it is not clear how a cognitive remediation intervention would be employed in multisite clinical trials. A meeting of experts on cognitive remediation and related methodological topics was convened to address the feasibility and study design issues for the development of a multisite trial of cognitive remediation in schizophrenia called the Cognitive Remediation in the Schizophrenia Trials Network study. This report details the findings from this meeting, which included the following 4 conclusions. (1) A multisite trial of a cognitive remediation intervention using a network of diverse research sites would be of great scientific value. (2) Various interventions could be employed for this multisite trial. (3) Programs that do not address key motivational and interpersonal aspects of cognitive remediation may benefit from supplementation with “bridging groups” that allows patients to meet with others and to apply their newly acquired cognitive skills to everyday life. (4) Before a multisite efficacy trial is initiated, a pilot study could demonstrate the feasibility of conducting a trial using a cognitive remediation intervention. PMID:20194249

  6. Observation of the origin of d0 magnetism in ZnO nanostructures using X-ray-based microscopic and spectroscopic techniques.

    PubMed

    Singh, Shashi B; Wang, Yu-Fu; Shao, Yu-Cheng; Lai, Hsuan-Yu; Hsieh, Shang-Hsien; Limaye, Mukta V; Chuang, Chen-Hao; Hsueh, Hung-Chung; Wang, Hsaiotsu; Chiou, Jau-Wern; Tsai, Hung-Ming; Pao, Chih-Wen; Chen, Chia-Hao; Lin, Hong-Ji; Lee, Jyh-Fu; Wu, Chun-Te; Wu, Jih-Jen; Pong, Way-Faung; Ohigashi, Takuji; Kosugi, Nobuhiro; Wang, Jian; Zhou, Jigang; Regier, Tom; Sham, Tsun-Kong

    2014-08-01

    Efforts have been made to elucidate the origin of d(0) magnetism in ZnO nanocactuses (NCs) and nanowires (NWs) using X-ray-based microscopic and spectroscopic techniques. The photoluminescence and O K-edge and Zn L3,2-edge X-ray-excited optical luminescence spectra showed that ZnO NCs contain more defects than NWs do and that in ZnO NCs, more defects are present at the O sites than at the Zn sites. Specifically, the results of O K-edge scanning transmission X-ray microscopy (STXM) and the corresponding X-ray-absorption near-edge structure (XANES) spectroscopy demonstrated that the impurity (non-stoichiometric) region in ZnO NCs contains a greater defect population than the thick region. The intensity of O K-edge STXM-XANES in the impurity region is more predominant in ZnO NCs than in NWs. The increase in the unoccupied (occupied) density of states at/above (at/below) the conduction-band minimum (valence-band maximum) or the Fermi level is related to the population of defects at the O sites, as revealed by comparing the ZnO NCs to the NWs. The results of O K-edge and Zn L3,2-edge X-ray magnetic circular dichroism demonstrated that the origin of magnetization is attributable to the O 2p orbitals rather than the Zn d orbitals. Further, the local density approximation (LDA) + U verified that vacancies in the form of dangling or unpaired 2p states (due to Zn vacancies) induced a significant local spin moment in the nearest-neighboring O atoms to the defect center, which was determined from the uneven local spin density by analyzing the partial density of states of O 2p in ZnO.

  7. How Institutional and University Counselor Policies Effectively Respond to Victims of Cyber Violent Acts: A Multisite Case Study

    ERIC Educational Resources Information Center

    Richards, Gretchen M.

    2012-01-01

    This multisite case study examined how institutional and university counselor policies effectively respond to cyber violent acts. Stake's (2006) multisite case study methodology was used to identify seven themes from current literature. Two sites with four participants were selected. The participants included two counseling directors and the…

  8. Middle-Eastern plant communities tolerate 9 years of drought in a multi-site climate manipulation experiment.

    PubMed

    Tielbörger, Katja; Bilton, Mark C; Metz, Johannes; Kigel, Jaime; Holzapfel, Claus; Lebrija-Trejos, Edwin; Konsens, Irit; Parag, Hadas A; Sternberg, Marcelo

    2014-10-06

    For evaluating climate change impacts on biodiversity, extensive experiments are urgently needed to complement popular non-mechanistic models which map future ecosystem properties onto their current climatic niche. Here, we experimentally test the main prediction of these models by means of a novel multi-site approach. We implement rainfall manipulations--irrigation and drought--to dryland plant communities situated along a steep climatic gradient in a global biodiversity hotspot containing many wild progenitors of crops. Despite the large extent of our study, spanning nine plant generations and many species, very few differences between treatments were observed in the vegetation response variables: biomass, species composition, species richness and density. The lack of a clear drought effect challenges studies classifying dryland ecosystems as most vulnerable to global change. We attribute this resistance to the tremendous temporal and spatial heterogeneity under which the plants have evolved, concluding that this should be accounted for when predicting future biodiversity change.

  9. A risk assessment method for multi-site damage

    NASA Astrophysics Data System (ADS)

    Millwater, Harry Russell, Jr.

    This research focused on developing probabilistic methods suitable for computing small probabilities of failure, e.g., 10sp{-6}, of structures subject to multi-site damage (MSD). MSD is defined as the simultaneous development of fatigue cracks at multiple sites in the same structural element such that the fatigue cracks may coalesce to form one large crack. MSD is modeled as an array of collinear cracks with random initial crack lengths with the centers of the initial cracks spaced uniformly apart. The data used was chosen to be representative of aluminum structures. The structure is considered failed whenever any two adjacent cracks link up. A fatigue computer model is developed that can accurately and efficiently grow a collinear array of arbitrary length cracks from initial size until failure. An algorithm is developed to compute the stress intensity factors of all cracks considering all interaction effects. The probability of failure of two to 100 cracks is studied. Lower bounds on the probability of failure are developed based upon the probability of the largest crack exceeding a critical crack size. The critical crack size is based on the initial crack size that will grow across the ligament when the neighboring crack has zero length. The probability is evaluated using extreme value theory. An upper bound is based on the probability of the maximum sum of initial cracks being greater than a critical crack size. A weakest link sampling approach is developed that can accurately and efficiently compute small probabilities of failure. This methodology is based on predicting the weakest link, i.e., the two cracks to link up first, for a realization of initial crack sizes, and computing the cycles-to-failure using these two cracks. Criteria to determine the weakest link are discussed. Probability results using the weakest link sampling method are compared to Monte Carlo-based benchmark results. The results indicate that very small probabilities can be computed

  10. Patterns of multisite pain and associations with risk factors

    PubMed Central

    Coggon, David; Ntani, Georgia; Palmer, Keith T.; Felli, Vanda E.; Harari, Raul; Barrero, Lope H.; Felknor, Sarah A.; Gimeno, David; Cattrell, Anna; Vargas-Prada, Sergio; Bonzini, Matteo; Solidaki, Eleni; Merisalu, Eda; Habib, Rima R.; Sadeghian, Farideh; Masood Kadir, M.; Warnakulasuriya, Sudath S.P.; Matsudaira, Ko; Nyantumbu, Busisiwe; Sim, Malcolm R.; Harcombe, Helen; Cox, Ken; Marziale, Maria H.; Sarquis, Leila M.; Harari, Florencia; Freire, Rocio; Harari, Natalia; Monroy, Magda V.; Quintana, Leonardo A.; Rojas, Marianela; Salazar Vega, Eduardo J.; Harris, E. Clare; Serra, Consol; Martinez, J. Miguel; Delclos, George; Benavides, Fernando G.; Carugno, Michele; Ferrario, Marco M.; Pesatori, Angela C.; Chatzi, Leda; Bitsios, Panos; Kogevinas, Manolis; Oha, Kristel; Sirk, Tuuli; Sadeghian, Ali; Peiris-John, Roshini J.; Sathiakumar, Nalini; Wickremasinghe, A. Rajitha; Yoshimura, Noriko; Kelsall, Helen L.; Hoe, Victor C.W; Urquhart, Donna M.; Derrett, Sarah; McBride, David; Herbison, Peter; Gray, Andrew

    2013-01-01

    To explore definitions for multisite pain, and compare associations with risk factors for different patterns of musculoskeletal pain, we analysed cross-sectional data from the Cultural and Psychosocial Influences on Disability (CUPID) study. The study sample comprised 12,410 adults aged 20–59 years from 47 occupational groups in 18 countries. A standardised questionnaire was used to collect information about pain in the past month at each of 10 anatomical sites, and about potential risk factors. Associations with pain outcomes were assessed by Poisson regression, and characterised by prevalence rate ratios (PRRs). Extensive pain, affecting 6–10 anatomical sites, was reported much more frequently than would be expected if the occurrence of pain at each site were independent (674 participants vs 41.9 expected). In comparison with pain involving only 1–3 sites, it showed much stronger associations (relative to no pain) with risk factors such as female sex (PRR 1.6 vs 1.1), older age (PRR 2.6 vs 1.1), somatising tendency (PRR 4.6 vs 1.3), and exposure to multiple physically stressing occupational activities (PRR 5.0 vs 1.4). After adjustment for number of sites with pain, these risk factors showed no additional association with a distribution of pain that was widespread according to the frequently used American College of Rheumatology criteria. Our analysis supports the classification of pain at multiple anatomical sites simply by the number of sites affected, and suggests that extensive pain differs importantly in its associations with risk factors from pain that is limited to only a small number of anatomical sites. PMID:23727463

  11. Spectroscopic characterization of the isolated SF6- and C4F8- anions: observation of very long harmonic progressions in symmetric deformation modes upon photodetachment.

    PubMed

    Bopp, Joseph C; Roscioli, Joseph R; Johnson, Mark A; Miller, Thomas M; Viggiano, A A; Villano, Stephanie M; Wren, Scott W; Lineberger, W Carl

    2007-02-22

    Spectroscopic studies of the SF6- and c-C4F8- anions are reported to provide experimental benchmarks for theoretical predictions of their structures and electron binding energies. The photoelectron spectrum of SF6- is dominated by a long progression in the S-F stretching mode, with an envelope consistent with theoretical predictions that the anion preserves the Oh symmetry of the neutral, but has a longer S-F bond length. This main progression occurs with an unexpectedly strong contribution from a second mode, however, whose characteristic energy does not correspond to any of the neutral SF6 fundamental vibrations in its ground electronic state. The resulting doublet pattern is evident when the bare ion is prepared with low internal energy content (i.e., using N2 carrier gas in a free jet or liquid nitrogen-cooling in a flowing afterglow) but is much better resolved in the spectrum of the SF6-.Ar complex. The infrared predissociation spectrum of SF6-.Ar consists of a strong band at 683(5) cm(-1), which we assign to the nu3 (t1u) fundamental, the same mode that yields the strong 948 cm(-1) infrared transition in neutral SF6. One qualitatively interesting aspect of the SF6- behavior is the simple structure of its photoelectron spectrum, which displays uncluttered, harmonic bands in an energy region where the neutral molecule contains about 2 eV of vibrational excitation. We explore this effect further in the c-C4F8- anion, which also presents a system that is calculated to undergo large, symmetrical distortion upon electron attachment to the neutral. The photoelectron spectrum of this species is dominated by a long, single vibrational progression, this time involving the symmetric ring-breathing mode. Like the SF6- case, the c-C4F8- spectrum is remarkably isolated and harmonic in spite of the significant internal excitation of a relatively complex molecular framework. Both these perfluorinated anions thus share the property that the symmetrical deformation of the

  12. Implementation and validation of a Wilks-type multi-site daily precipitation generator over a typical Alpine river catchment

    NASA Astrophysics Data System (ADS)

    Keller, D. E.; Fischer, A. M.; Frei, C.; Liniger, M. A.; Appenzeller, C.; Knutti, R.

    2015-05-01

    Many climate impact assessments require high-resolution precipitation time series that have a spatio-temporal correlation structure consistent with observations, for simulating either current or future climate conditions. In this respect, weather generators (WGs) designed and calibrated for multiple sites are an appealing statistical downscaling technique to stochastically simulate multiple realisations of possible future time series consistent with the local precipitation characteristics and their expected future changes. In this study, we present the implementation and validation of a multi-site daily precipitation generator re-built after the methodology described in Wilks (1998). The generator consists of several Richardson-type WGs run with spatially correlated random number streams. This study aims at investigating the capabilities, the added value and the limitations of the precipitation generator for a typical Alpine river catchment in the Swiss Alpine region under current climate. The calibrated multi-site WG is skilful at individual sites in representing the annual cycle of the precipitation statistics, such as mean wet day frequency and intensity as well as monthly precipitation sums. It reproduces realistically the multi-day statistics such as the frequencies of dry and wet spell lengths and precipitation sums over consecutive wet days. Substantial added value is demonstrated in simulating daily areal precipitation sums in comparison to multiple WGs that lack the spatial dependency in the stochastic process. Limitations are seen in reproducing daily and multi-day extreme precipitation sums, observed variability from year to year and in reproducing long dry spell lengths. Given the performance of the presented generator, we conclude that it is a useful tool to generate precipitation series consistent with the mean climatic aspects and likely helpful to be used as a downscaling technique for climate change scenarios.

  13. Tools and Methods for Risk Management in Multi-Site Engineering Projects

    NASA Astrophysics Data System (ADS)

    Zhou, Mingwei; Nemes, Laszlo; Reidsema, Carl; Ahmed, Ammar; Kayis, Berman

    In today's highly global business environment, engineering and manufacturing projects often involve two or more geographically dispersed units or departments, research centers or companies. This paper attempts to identify the requirements for risk management in a multi-site engineering project environment, and presents a review of the state-of-the-art tools and methods that can be used to manage risks in multi-site engineering projects. This leads to the development of a risk management roadmap, which will underpin the design and implementation of an intelligent risk mapping system.

  14. Observation of the origin of d0 magnetism in ZnO nanostructures using X-ray-based microscopic and spectroscopic techniques

    NASA Astrophysics Data System (ADS)

    Singh, Shashi B.; Wang, Yu-Fu; Shao, Yu-Cheng; Lai, Hsuan-Yu; Hsieh, Shang-Hsien; Limaye, Mukta V.; Chuang, Chen-Hao; Hsueh, Hung-Chung; Wang, Hsaiotsu; Chiou, Jau-Wern; Tsai, Hung-Ming; Pao, Chih-Wen; Chen, Chia-Hao; Lin, Hong-Ji; Lee, Jyh-Fu; Wu, Chun-Te; Wu, Jih-Jen; Pong, Way-Faung; Ohigashi, Takuji; Kosugi, Nobuhiro; Wang, Jian; Zhou, Jigang; Regier, Tom; Sham, Tsun-Kong

    2014-07-01

    Efforts have been made to elucidate the origin of d0 magnetism in ZnO nanocactuses (NCs) and nanowires (NWs) using X-ray-based microscopic and spectroscopic techniques. The photoluminescence and O K-edge and Zn L3,2-edge X-ray-excited optical luminescence spectra showed that ZnO NCs contain more defects than NWs do and that in ZnO NCs, more defects are present at the O sites than at the Zn sites. Specifically, the results of O K-edge scanning transmission X-ray microscopy (STXM) and the corresponding X-ray-absorption near-edge structure (XANES) spectroscopy demonstrated that the impurity (non-stoichiometric) region in ZnO NCs contains a greater defect population than the thick region. The intensity of O K-edge STXM-XANES in the impurity region is more predominant in ZnO NCs than in NWs. The increase in the unoccupied (occupied) density of states at/above (at/below) the conduction-band minimum (valence-band maximum) or the Fermi level is related to the population of defects at the O sites, as revealed by comparing the ZnO NCs to the NWs. The results of O K-edge and Zn L3,2-edge X-ray magnetic circular dichroism demonstrated that the origin of magnetization is attributable to the O 2p orbitals rather than the Zn d orbitals. Further, the local density approximation (LDA) + U verified that vacancies in the form of dangling or unpaired 2p states (due to Zn vacancies) induced a significant local spin moment in the nearest-neighboring O atoms to the defect center, which was determined from the uneven local spin density by analyzing the partial density of states of O 2p in ZnO.Efforts have been made to elucidate the origin of d0 magnetism in ZnO nanocactuses (NCs) and nanowires (NWs) using X-ray-based microscopic and spectroscopic techniques. The photoluminescence and O K-edge and Zn L3,2-edge X-ray-excited optical luminescence spectra showed that ZnO NCs contain more defects than NWs do and that in ZnO NCs, more defects are present at the O sites than at the Zn sites

  15. Spectroscopic measurements of solar wind generation

    NASA Technical Reports Server (NTRS)

    Kohl, J. L.; Withbroe, G. L.; Zapata, C. A.; Noci, G.

    1983-01-01

    Spectroscopically observable quantities are described which are sensitive to the primary plasma parameters of the solar wind's source region. The method is discussed in which those observable quantities are used as constraints in the construction of empirical models of various coronal structures. Simulated observations are used to examine the fractional contributions to observed spectral intensities from coronal structures of interest which co-exist with other coronal structures along simulated lines-of-sight. The sensitivity of spectroscopic observables to the physical parameters within each of those structures is discussed.

  16. Spectroscopic ellipsometry on lamellar gratings

    NASA Astrophysics Data System (ADS)

    Antos, R.; Ohlidal, I.; Mistrik, J.; Murakami, K.; Yamaguchi, T.; Pistora, J.; Horie, M.; Visnovsky, S.

    2005-05-01

    Deep lamellar diffraction gratings fabricated by etching a transparent quartz plate are studied using spectroscopic ellipsometry. The rigorous coupled-wave analysis is used to calculate the optical response of the gratings. Three parameters of the rectangular profile are determined by utilizing the least-square method. Detailed investigation of the spectral dependences demonstrates the uniqueness of the solution. Observing the spectral dependences of Wood anomalies suggests that even complicated profiles can be fitted with high authenticity.

  17. Single nanoparticle tracking spectroscopic microscope

    DOEpatents

    Yang, Haw; Cang, Hu; Xu, Cangshan; Wong, Chung M.

    2011-07-19

    A system that can maintain and track the position of a single nanoparticle in three dimensions for a prolonged period has been disclosed. The system allows for continuously imaging the particle to observe any interactions it may have. The system also enables the acquisition of real-time sequential spectroscopic information from the particle. The apparatus holds great promise in performing single molecule spectroscopy and imaging on a non-stationary target.

  18. Ground state dissociation pathways for 3,4,-dichloro-1,2,5-thiadiazole: Spectroscopic observation and fate of NCsbnd C(Cl2)sbnd Ndbnd S isomer

    NASA Astrophysics Data System (ADS)

    Srinivas, D.; Upadhyaya, Hari P.

    2016-09-01

    Photodissociation pathways for 3,4-dichloro-1,2,5-thiadiazole was investigated in its ground state at various wavelengths in the UV region. The photolysis products were identified by the UV absorption and emission spectroscopy. Molecular chlorine (Cl2) elimination was observed using absorption methods in the UV region. UV absorption and quantum calculation confirms the migration of chlorine atom and subsequent ring opening to form NCsbnd C(Cl2)sbnd Ndbnd S isomer. Multiphotonic excitation leading to the UV emission in the vicinity of 389 nm was observed due to the formation of CN(B2Σ+) moiety. New UV absorption bands observed at ∼255 and ∼290 nm were assigned to the its isomer NCsbnd C(Cl2)sbnd Ndbnd S.

  19. Simultaneous retrieval of atmospheric CO2 and light path modification from space-based spectroscopic observations of greenhouse gases: methodology and application to GOSAT measurements over TCCON sites.

    PubMed

    Oshchepkov, Sergey; Bril, Andrey; Yokota, Tatsuya; Yoshida, Yukio; Blumenstock, Thomas; Deutscher, Nicholas M; Dohe, Susanne; Macatangay, Ronald; Morino, Isamu; Notholt, Justus; Rettinger, Markus; Petri, Christof; Schneider, Matthias; Sussman, Ralf; Uchino, Osamu; Velazco, Voltaire; Wunch, Debra; Belikov, Dmitry

    2013-02-20

    This paper presents an improved photon path length probability density function method that permits simultaneous retrievals of column-average greenhouse gas mole fractions and light path modifications through the atmosphere when processing high-resolution radiance spectra acquired from space. We primarily describe the methodology and retrieval setup and then apply them to the processing of spectra measured by the Greenhouse gases Observing SATellite (GOSAT). We have demonstrated substantial improvements of the data processing with simultaneous carbon dioxide and light path retrievals and reasonable agreement of the satellite-based retrievals against ground-based Fourier transform spectrometer measurements provided by the Total Carbon Column Observing Network (TCCON).

  20. Simultaneous retrieval of atmospheric CO2 and light path modification from space-based spectroscopic observations of greenhouse gases: methodology and application to GOSAT measurements over TCCON sites.

    PubMed

    Oshchepkov, Sergey; Bril, Andrey; Yokota, Tatsuya; Yoshida, Yukio; Blumenstock, Thomas; Deutscher, Nicholas M; Dohe, Susanne; Macatangay, Ronald; Morino, Isamu; Notholt, Justus; Rettinger, Markus; Petri, Christof; Schneider, Matthias; Sussman, Ralf; Uchino, Osamu; Velazco, Voltaire; Wunch, Debra; Belikov, Dmitry

    2013-02-20

    This paper presents an improved photon path length probability density function method that permits simultaneous retrievals of column-average greenhouse gas mole fractions and light path modifications through the atmosphere when processing high-resolution radiance spectra acquired from space. We primarily describe the methodology and retrieval setup and then apply them to the processing of spectra measured by the Greenhouse gases Observing SATellite (GOSAT). We have demonstrated substantial improvements of the data processing with simultaneous carbon dioxide and light path retrievals and reasonable agreement of the satellite-based retrievals against ground-based Fourier transform spectrometer measurements provided by the Total Carbon Column Observing Network (TCCON). PMID:23435008

  1. Testing the Feasibility of Fidelity Evaluation in a Multisite, Multiprogram Initiative

    ERIC Educational Resources Information Center

    Cornish, Disa Lubker; Losch, Mary E.; Avery, Mitchell

    2016-01-01

    Monitoring fidelity of implementation is a critical task when initiating evidence-based programs. This pilot study sought to identify best practices in a fidelity monitoring process and determine the feasibility of continuing a fidelity monitoring process with a multisite, multiprogram initiative. A fidelity log was created for each of 11…

  2. Documenting the Impact of Multisite Evaluations on the Science, Technology, Engineering, and Mathematics Field

    ERIC Educational Resources Information Center

    Roseland, Denise; Greenseid, Lija O.; Volkov, Boris B.; Lawrenz, Frances

    2011-01-01

    This chapter discusses the impact that four multisite National Science Foundation (NSF) evaluations had on the broader field of science, technology, engineering, and mathematics education and evaluation. Three approaches were used to investigate the broader impact of these evaluations on the field: (a) a citation analysis, (b) an on-line survey,…

  3. The Validation of the Evaluation Involvement Scale for Use in Multisite Settings

    ERIC Educational Resources Information Center

    Toal, Stacie A.

    2009-01-01

    Evaluation researchers and practitioners acknowledge that involving stakeholders in the planning and implementation of an evaluation increases buy-in, understanding, and use. With the recent increase in multi-site evaluations of large federal programs, evaluators must think differently about how to encourage meaningful collaboration by…

  4. Intraclass Correlations for Three-Level Multi-Site Cluster-Randomized Trials of Science Achievement

    ERIC Educational Resources Information Center

    Westine, Carl D.

    2015-01-01

    A cluster-randomized trial (CRT) relies on random assignment of intact clusters to treatment conditions, such as classrooms or schools (Raudenbush & Bryk, 2002). One specific type of CRT, a multi-site CRT (MSCRT), is commonly employed in educational research and evaluation studies (Spybrook & Raudenbush, 2009; Spybrook, 2014; Bloom,…

  5. Brief Treatments for Cannabis Dependence: Findings From a Randomized Multisite Trial

    ERIC Educational Resources Information Center

    Babor, Thomas F.

    2004-01-01

    This study evaluated the efficacy of 2 brief interventions for cannabis-dependent adults. A multisite randomized controlled trial compared cannabis use outcomes across 3 study conditions: (a) 2 sessions of motivational enhancement therapy (MET); (b) 9 sessions of multicomponent therapy that included MET, cognitive-behavioral therapy, and case…

  6. Multi-Site Ethnography, Hypermedia and the Productive Hazards of Digital Methods: A Struggle for Liveness

    ERIC Educational Resources Information Center

    Gallagher, Kathleen; Freeman, Barry

    2011-01-01

    This article explores the possibilities and frustrations of using digital methods in a multi-sited ethnographic research project. The project, "Urban School Performances: The interplay, through live and digital drama, of local-global knowledge about student engagement", is a study of youth and teachers in drama classrooms in contexts of schooling…

  7. Power Calculations for Moderators in Multi-Site Cluster Randomized Trials

    ERIC Educational Resources Information Center

    Spybrook, Jessaca; Kelcey, Ben; Dong, Nianbo

    2016-01-01

    Cluster randomized trials (CRTs), or studies in which intact groups of individuals are randomly assigned to a condition, are becoming more common in evaluation studies of educational programs. A specific type of CRT in which clusters are randomly assigned to treatment within blocks or sites, known as multisite cluster randomized trials (MSCRTs),…

  8. Positive Family Intervention for Severe Challenging Behavior I: A Multisite Randomized Clinical Trial

    ERIC Educational Resources Information Center

    Durand, V. Mark; Hieneman, Meme; Clarke, Shelley; Wang, Mo; Rinaldi, Melissa L.

    2013-01-01

    The present study was a multisite randomized clinical trial assessing the effects of adding a cognitive-behavioral intervention to positive behavior support (PBS). Fifty-four families who met the criteria of (a) having a child with a developmental disability, (b) whose child displayed serious challenging behavior (e.g., aggression, self-injury,…

  9. The 2002 Multisite Conference on the Future of School Psychology: Next Steps

    ERIC Educational Resources Information Center

    Dawson, Margaret; Cummings, Jack A.; Harrison, Patti L.; Short, Rick J.; Gorin, Susan; Palomares, Ron

    2003-01-01

    Eleven broad themes emerged from the 2002 multisite conference on the Future of School Psychology. After the conference, strategies developed by the participants were clustered into the following domains: (a) advocacy and public policy; (b) research and knowledge base; (c) collaboration and communication; (d) practice; (e) preservice training; and…

  10. The 2002 Multisite Conference on the Future of School Psychology: Next Steps

    ERIC Educational Resources Information Center

    Dawson, Margaret; Cummings, Jack A.; Harrison, Patti L.; Short, Rick J.; Gorin, Susan; Palomares, Ron

    2004-01-01

    Eleven broad themes emerged from the 2002 multisite conference on the Future of School Psychology. After the conference, strategies developed by the participants were clustered into the following domains: (a) advocacy and public policy; (b) research and knowledge base; (c) collaboration and communication; (d) practice; (e) preservice training; and…

  11. Childhood Traumatic Grief: A Multi-Site Empirical Examination of the Construct and Its Correlates

    ERIC Educational Resources Information Center

    Brown, Elissa J.; Amaya-Jackson, Lisa; Cohen, Judith; Handel, Stephanie; De Bocanegra, Heike Thiel; Zatta, Eileen; Goodman, Robin F.; Mannarino, Anthony

    2008-01-01

    This study evaluated the construct of childhood traumatic grief (CTG) and its correlates through a multi-site assessment of 132 bereaved children and adolescents. Youth completed a new measure of the characteristics, attributions, and reactions to exposure to death (CARED), as well as measures of CTG, posttraumatic stress disorder (PTSD),…

  12. A Multisite Psychotherapy and Medication Trial for Depressed Adolescents: Background and Benefits

    ERIC Educational Resources Information Center

    Kratochvil, Christopher J.; Simons, Anne; Vitiello, Benedetto; Walkup, John; Emslie, Graham; Rosenberg, David; March, John S.

    2005-01-01

    The Treatment for Adolescents With Depression Study (TADS) is an NIMH-supported multisite clinical trial that compares the effectiveness of a depression-specific cognitive behavioral therapy (CBT), medication management with fluoxetine (FLX), the combination of CBT and FLX (COMB), and medical management with pill placebo (PBO). TADS was…

  13. Toward Better Research on--and Thinking about--Evaluation Influence, Especially in Multisite Evaluations

    ERIC Educational Resources Information Center

    Mark, Melvin M.

    2011-01-01

    Evaluation is typically carried out with the intention of making a difference in the understandings and actions of stakeholders and decision makers. The author provides a general review of the concepts of evaluation "use," evaluation "influence," and "influence pathways," with connections to multisite evaluations. The study of evaluation influence…

  14. Parental Engagement in Home Visiting Programs--Findings from the Parents as Teachers Multisite Evaluation.

    ERIC Educational Resources Information Center

    Wagner, Mary; Spiker, Donna; Gerlach-Downie, Suzanne; Hernandez, Frances

    This report presents the findings of a reassessment of an ongoing, multi-site evaluation of the Parents as Teachers (PAT) home visiting program. The evaluation had, from its inception, included data collection and analyses regarding engagement; however, a reassessment of research questions driving the evaluation shifted engagement from a secondary…

  15. Learning about and from a Distribution of Program Impacts Using Multisite Trials

    ERIC Educational Resources Information Center

    Raudenbush, Stephen W.; Bloom, Howard S.

    2015-01-01

    The present article provides a synthesis of the conceptual and statistical issues involved in using multisite randomized trials to learn about and from a distribution of heterogeneous program impacts across individuals and/or program sites. Learning "about" such a distribution involves estimating its mean value, detecting and quantifying…

  16. Statistical Analysis for Multisite Trials Using Instrumental Variables with Random Coefficients

    ERIC Educational Resources Information Center

    Raudenbush, Stephen W.; Reardon, Sean F.; Nomi, Takako

    2012-01-01

    Multisite trials can clarify the average impact of a new program and the heterogeneity of impacts across sites. Unfortunately, in many applications, compliance with treatment assignment is imperfect. For these applications, we propose an instrumental variable (IV) model with person-specific and site-specific random coefficients. Site-specific IV…

  17. Simultaneous high and moderate spectroscopic observations of Saturn at selected locations on the disk in the 6000-6825 A region

    NASA Astrophysics Data System (ADS)

    Moreno, F.; Molina, A.

    1990-04-01

    Moderate and high-resolution spectra have been obtained at various positions on Saturn's disk in the spectral range 6000-6825 A. The observations were carried out using the 2.2 m and 1.52 m telescopes at the Calar Alto Observatory (Spain) simultaneously. The spatial variations of the equivalent widths of the absorption features of H2, CH4, and NH3 existing in this spectral range are shown and compared with those obtained by other scientists. These results are used to constrain some typical atmospheric parameters. An inhomogeneous cloud model for the atmosphere of Saturn is used in which an extended haze overlies a dense cloud deck. The optical depth of the haze is constrainted by the observations to the value of about 13 in the equation region. The model is consistent with an enrichment of carbon in Saturn's atmosphere by a factor of two with respect to the solar value.

  18. Biasing Potential Replica Exchange Multi-Site λ-Dynamics for Efficient Free Energy Calculations

    PubMed Central

    Armacost, Kira A.; Goh, Garrett B.; Brooks, Charles L.

    2016-01-01

    Traditional free energy calculation methods are well known for their drawbacks in scalability and speed in converging results particularly for calculations with large perturbations. In the present work, we report on the development of biasing potential replica exchange multi-site λ-dynamics (BP-REX MSλD), which is a free energy method that is capable of performing simultaneous alchemical free energy transformations, including perturbations between flexible moieties. BP-REX MSλD and the original MSλD are applied to a series of symmetrical 2,5-benzoquinone derivatives covering a diverse chemical space and range of conformational flexibility. Improved λ-space sampling is observed for the BP-REX MSλD simulations, yielding a 2–5-fold increase in the number of transitions between substituents compared to traditional MSλD. We also demonstrate the efficacy of varying the value of c, the parameter that controls the ruggedness of the landscape mediating the sampling of λ-states, based on the flexibility of the fragment. Finally, we developed a protocol for maximizing the transition frequency between fragments. This protocol reduces the “kinetic barrier” for alchemically transforming fragments by grouping and ordering based on volume. These findings are applied to a challenging test set involving a series of geldanamycin-based inhibitors of heat shock protein 90 (Hsp90). Even though the perturbations span volume changes by as large as 60 Å3, the values for the free energy change achieve an average unsigned error (AUE) of 1.5 kcal/mol relative to experimental Kd measurements with a reasonable correlation (R = 0.56). Our results suggest that the BP-REX MSλD algorithm is a highly efficient and scalable free energy method, which when utilized will enable routine calculations on the order of hundreds of compounds using only a few simulations. PMID:26579773

  19. Resolving Spectral Lines with a Periscope-Type DVD Spectroscope

    ERIC Educational Resources Information Center

    Wakabayashi, Fumitaka

    2008-01-01

    A new type of DVD spectroscope, the periscope type, is described and the numerical analysis of the observed emission and absorption spectra is demonstrated. A small and thin mirror is put inside and an eighth part of a DVD is used as a grating. Using this improved DVD spectroscope, one can observe and photograph visible spectra more easily and…

  20. Spectroscopic optical coherence elastography

    PubMed Central

    Adie, Steven G.; Liang, Xing; Kennedy, Brendan F.; John, Renu; Sampson, David D.; Boppart, Stephen A.

    2010-01-01

    We present an optical technique to image the frequency-dependent complex mechanical response of a viscoelastic sample. Three-dimensional hyperspectral data, comprising two-dimensional B-mode images and a third dimension corresponding to vibration frequency, were acquired from samples undergoing external mechanical excitation in the audio-frequency range. We describe the optical coherence tomography (OCT) signal when vibration is applied to a sample and detail the processing and acquisition techniques used to extract the local complex mechanical response from three-dimensional data that, due to a wide range of vibration frequencies, possess a wide range of sample velocities. We demonstrate frequency-dependent contrast of the displacement amplitude and phase of a silicone phantom containing inclusions of higher stiffness. Measurements of an ex vivo tumor margin demonstrate distinct spectra between adipose and tumor regions, and images of displacement amplitude and phase demonstrated spatially-resolved contrast. Contrast was also observed in displacement amplitude and phase images of a rat muscle sample. These results represent the first demonstration of mechanical spectroscopy based on B-mode OCT imaging. Spectroscopic optical coherence elastography (S-OCE) provides a high-resolution imaging capability for the detection of tissue pathologies that are characterized by a frequency-dependent viscoelastic response. PMID:21164898

  1. Spectroscopic optical coherence elastography.

    PubMed

    Adie, Steven G; Liang, Xing; Kennedy, Brendan F; John, Renu; Sampson, David D; Boppart, Stephen A

    2010-12-01

    We present an optical technique to image the frequency-dependent complex mechanical response of a viscoelastic sample. Three-dimensional hyperspectral data, comprising two-dimensional B-mode images and a third dimension corresponding to vibration frequency, were acquired from samples undergoing external mechanical excitation in the audio-frequency range. We describe the optical coherence tomography (OCT) signal when vibration is applied to a sample and detail the processing and acquisition techniques used to extract the local complex mechanical response from three-dimensional data that, due to a wide range of vibration frequencies, possess a wide range of sample velocities. We demonstrate frequency-dependent contrast of the displacement amplitude and phase of a silicone phantom containing inclusions of higher stiffness. Measurements of an ex vivo tumor margin demonstrate distinct spectra between adipose and tumor regions, and images of displacement amplitude and phase demonstrated spatially-resolved contrast. Contrast was also observed in displacement amplitude and phase images of a rat muscle sample. These results represent the first demonstration of mechanical spectroscopy based on B-mode OCT imaging. Spectroscopic optical coherence elastography (S-OCE) provides a high-resolution imaging capability for the detection of tissue pathologies that are characterized by a frequency-dependent viscoelastic response. PMID:21164898

  2. Calibration method for spectroscopic systems

    DOEpatents

    Sandison, David R.

    1998-01-01

    Calibration spots of optically-characterized material placed in the field of view of a spectroscopic system allow calibration of the spectroscopic system. Response from the calibration spots is measured and used to calibrate for varying spectroscopic system operating parameters. The accurate calibration achieved allows quantitative spectroscopic analysis of responses taken at different times, different excitation conditions, and of different targets.

  3. Calibration method for spectroscopic systems

    DOEpatents

    Sandison, D.R.

    1998-11-17

    Calibration spots of optically-characterized material placed in the field of view of a spectroscopic system allow calibration of the spectroscopic system. Response from the calibration spots is measured and used to calibrate for varying spectroscopic system operating parameters. The accurate calibration achieved allows quantitative spectroscopic analysis of responses taken at different times, different excitation conditions, and of different targets. 3 figs.

  4. Spectroscopic Observation of the Stardust Re-Entry in the Near UV with SLIT: Deduction of Surface Temperatures and Plasma Radiation

    NASA Technical Reports Server (NTRS)

    Winter, Michael W.; Trumble, Kerry A.

    2010-01-01

    Thermal radiation of the heat-shield and the emission of the post-shock layer around the Stardust capsule, during its re-entry, were detected by a NASA-led observation campaign aboard NASA's DC-8 airborne observatory involving teams from several nations. The German SLIT experiment used a conventional spectrometer, in a Czerny-Turner configuration (300 mm focal length and a 600 lines/mm grating), fed by fiber optics, to cover a wavelength range from 324 nm to 456 nm with a pixel resolution of 0.08 nm. The reentering spacecraft was tracked m uansuinaglly a camera with a view angle of 20 degrees, and light from the capsule was collected using a small mirror telescope with a view angle of only 0.45 degrees. Data were gathered with a measurement frequency of 5 Hz in a 30-second time interval around the point of maximum heating until the capsule left the field of view. The emission of CN (as a major ablation product), N2(+) and different atoms were monitored successfully during that time. Due to the nature of the experimental set up, spatial resolution of the radiation field was not possible. Therefore, all measured values represent an integration of radiation from the visible part of the glowing heat shield, and from the plasma in the post-shock region. Further, due to challenges in tracking not every spectrum gathered contained data. The measured spectra can be split up into two parts: (i) continuum spectra which represent a superposition of the heat shield radiation and the continuum radiation of potential dust particles in the plasma, and (ii) line spectra from the plasma in the shock layer. Planck temperatures (interpreted as the surface temperatures of the Stardust heat shield) were determined assuming either a constant surface temperature, or a temperature distribution deduced from numerical simulation. The constant surface temperatures are in good agreement with numerical simulations, but the peak values at the stagnation point are significantly lower than those

  5. Spectroscopic observations of 14N/15N ratios in both NH2 and CN in comet C/2013 US10 (Catalina)

    NASA Astrophysics Data System (ADS)

    Shinnaka, Yoshiharu; Kawakita, Hideyo

    2016-10-01

    Comet is one of the primordial small bodies in the solar system and probably it has kept the information about the evolution of materials from the pre-solar molecular cloud to the solar nebula.Isotopic ratio in volatiles is one of the primordial properties of comets. A heavier isotopes trend to be captured into a molecule by chemical reactions under very low-temperature conditions (called as fractionation). For instance, D/H ratio of water (HDO/H2O) in comet is enriched in D atom than the elemental abundance ratios of D/H in entire solar system [1]. Based on the observed D/H ratios in cometary water, a presumed temperature is ~20–50 K as the formation temperature of water (most abundant volatiles in cometary nucleus), by assuming water formed in gas-phase chemistry [2].Besides, the nitrogen isotopic ratios (14N/15N) have been determined from CN and HCN (which is believed a dominant "parent" species of CN in the coma) in >20 comets [3,4]. They demonstrated cometary HCN and CN show high 15N-fractionation with respect to the proto-solar value by a factor of ~3 and with a small diversity. Moreover, 14N/15N ratios in NH3 in comets has been determined from intensity ratios of NH2 isotopologues [5,6,7], and both 15N-fractionation as much as HCN in comets and a small diversity are seen in those 14N/15N ratios in NH3. However, there is a few reports about 14N/15N ratios in both HCN and NH3 in the same comets, and discussions about the relationship between these 14N/15N ratios have not been yet.We present 14N/15N ratios in both NH2 and CN in comet C/2013 US10 (Catalina). High-resolution optical spectra of the comet were taken with the HDS spectrograph mounted on the Subaru Telescope (Hawaii) on UT 2016 January 2–3. We will discuss about the origins of these volatiles based on the 14N/15N ratios.This work was supported by Graint-in-Aid for JSPS Fellows, 15J10864 (YS).References:[1] Lis et al., 2013, ApJ 774, L3[2] Millar et al., 1989, ApJ 340, 906[3] Bockelée-Morvan et

  6. Synchrotron-based far-infrared spectroscopic investigation and ab initio calculations of 3-oxetanone: observation and analysis of the ν7 band and the Coriolis coupled ν16 and ν20 bands.

    PubMed

    Chen, Ziqiu; van Wijngaarden, Jennifer

    2012-09-27

    Rotationally resolved vibrational spectra of the four-membered heterocycle 3-oxetanone (c-C(3)H(4)O(2)) have been investigated in the 360-720 cm(-1) region with a resolution of 0.000 959 cm(-1) using synchrotron radiation from the Canadian Light Source. The observed bands correspond to motions best described as C═O deformation out-of-plane (ν(20)) at 399.6 cm(-1), C═O deformation in-plane (ν(16)) at 448.2 cm(-1), and the ring deformation (ν(7)) at 685.0 cm(-1). Infrared ground state combination differences along with previously reported pure rotational transitions were used to obtain the ground state spectroscopic parameters. Band centers, rotational and centrifugal distortion constants for the ν(7), ν(16), and ν(20) vibrational excited states were accurately determined by fitting a total of 10,319 assigned rovibrational transitions in a global analysis. The two adjacent carbonyl deformation bands, ν(16) and ν(20), were found to be mutually perturbed through a first-order a-type Coriolis interaction which was accounted for in the multiband analysis. The band centers agree within 3% of the ab initio estimates using DFT theory.

  7. A comparison of multi-site daily rainfall downscaling techniques under Australian conditions

    NASA Astrophysics Data System (ADS)

    Frost, Andrew J.; Charles, Stephen P.; Timbal, Bertrand; Chiew, Francis H. S.; Mehrotra, R.; Nguyen, Kim C.; Chandler, Richard E.; McGregor, John L.; Fu, Guobin; Kirono, Dewi G. C.; Fernandez, Elodie; Kent, David M.

    2011-09-01

    SummarySix methods of downscaling GCM simulations to multi-site daily precipitation were applied to a set of 30 rain gauges located within South-Eastern Australia. The methods were tested at reproducing a range of statistics important within hydrological studies including inter-annual variability and spatial coherency using both NCEP/NCAR reanalysis and GCM predictors, thus testing the validity of GCM downscaled predictions. The methods evaluated, all having found application in Australia previously, are: (1) the dynamical downscaling Conformal-Cubic Atmospheric Model (CCAM) of McGregor (2005); the historical data based (2) Scaling method applied by Chiew et al. (2009) and (3) Analogue method of Timbal (2004); and three stochastic methods, (4) the GLIMCLIM (Generalised Linear Model for daily Climate time series) software package ( Chandler, 2002), (5) the Non-homogeneous Hidden Markov Model (NHMM) of Charles et al. (1999), and (6) the modified Markov model-kernel probability density estimation (MMM-KDE) downscaling technique of Mehrotra and Sharma (2007). The results showed that the simple Scaling approach provided relatively robust results for a range of statistics when GCM forcing data was used, and was therefore recommended for regional water availability and planning studies (subject to certain limitations as mentioned in conclusion section). The stochastic methods better capture changes to a fuller range of rainfall statistics and are recommended for detailed catchment modelling studies. In particular, the stochastic methods show better results for daily extreme rainfall (e.g. flooding/low flow) as the simulations are not based purely on temporal/spatial rainfall patterns observed in the past, and a hybrid GLIMCLIM occurrence-KDE amounts model is recommended based on performance for individual statistics. For GCM downscaled simulations, biases in annual mean and standard deviation of ±5% and -30% were observed typically, and no single model performed well

  8. Sonication effect on the reaction of 4-bromo-1-methylbenzene with sodium sulfide in liquid-liquid multi-site phase-transfer catalysis condition - kinetic study.

    PubMed

    Abimannan, Pachaiyappan; Selvaraj, Varathan; Rajendran, Venugopal

    2015-03-01

    The synthesis of di-p-tolylsulfane from the reaction of 4-bromo-1-methylbenzene (BMB) with sodium sulfide was carried out using a multi-site phase-transfer catalyst (MPTC) viz., 1,4-dihexyl-1,4-diazoniabicyclo[2.2.2]octanium dibromide and ultrasonic irradiation in a liquid-liquid reaction condition. The overall reaction rate is greatly enhanced when catalyzed by multi-site phase-transfer catalyst (MPTC) combined with sonication (40 kHz, 300 W) in a batch reactor than catalyzed by MPTC without sonication. Effects on the reaction due to various operating conditions, such as agitation speed, different ultrasound frequencies, different phase-transfer catalysts, different organic solvents, the amount of MPTC, temperature, amount of sodium sulfide, effect of sodium hydroxide, volume of n-hexane and the concentration of 4-bromo-1-methylbenzene. The reaction obeys a pseudo first-order rate law and a suitable mechanism was proposed based on the experimental observation.

  9. Spectroscopic observations of comet Austin (1989c)

    NASA Technical Reports Server (NTRS)

    Heyd, Rodney; Wyckoff, Susan; Wehinger, Peter; Mack, Peter

    1992-01-01

    Longslit CCD spectra (lambda = 5100-6400 A, delta(lambda) approximately 3 A) were obtained with the Michigan-Dartmouth-MIT 1.3 meter telescope in May 1990 (r = 0.74 AU, delta = 0.50 AU). The spectra were reduced with the Interactive data Reduction and Analysis Facility (IRAF). Spectral extractions offset sunward and tailward from the nucleus were analyzed. Species identified in the spectra include the following: C2, NH2(10-0), NH2(9-0), H2O(+), and CO(+). Spatial extractions of rotational line intensities in the NH2(10-0) band extend approximately 10(exp 4.5) km from the nucleus. A fit of the vectorial model to the NH2(10-0) spatial profile is consistent with an NH3 parent molecule. The NH2 production rate and an ammonia to water abundance ratio, NH3/H2O approximately 3 percent, were derived. The ammonia abundance obtained for comet Austin is consistent with that found for several other comets and is indicative of comet formation under very homogeneous conditions.

  10. Spectroscopic Classification of PS16ccj with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-05-01

    We report the classification of PS16ccj from spectroscopic observation with KOSMOS on the Mayall telescope. The observation was made on 2016 May 05 UT. We classify PS16ccj as a SN Ia near maximum light.

  11. Evaluating the Impact of Interventions in the Multisite Violence Prevention Study

    PubMed Central

    Miller-Johnson, Shari; Sullivan, Terri N.; Simon, Thomas R.

    2009-01-01

    This paper discusses the procedures and measures that were developed and utilized to evaluate the impact of the GREAT (Guiding Responsibility and Expectations in Adolescents Today and Tomorrow) programs in the Multisite Violence Prevention Project (MVPP). First, we describe the three different samples used to examine the impact of the programs, and the different sources of data used to assess these samples. Next, we outline procedures used to collect and manage the data. In the last section, we summarize the final set of measures selected for use in this study. Throughout the paper, we highlight ways in which the participating institutions collaborated to develop consistent procedures for use across the four sites. Overall, the paper provides important information related to the evaluation of violence prevention efforts, particularly for working effectively in multisite collaborative studies. PMID:14732187

  12. Issues in Designing and Implementing a Spanish-Language Multi-Site Clinical Trial

    PubMed Central

    Suarez-Morales, Lourdes; Matthews, Julie; Martino, Steve; Ball, Samuel A.; Rosa, Carmen; Farentinos, Christine; Szapocznik, José; Carroll, Kathleen M.

    2013-01-01

    To address at least in part health disparities in Hispanic populations, the NIDA Clinical Trials Network implemented the first multi-site randomized clinical trial of substance abuse treatment conducted entirely in Spanish. This trial was intended to evaluate the effectiveness of Motivational Enhancement Therapy in a diverse population of Hispanics. In the conduct of this trial, several barriers to the successful implementation of a Spanish-language multi-site trial had to be addressed, including the appropriate translation of assessment instruments, shortage of appropriately trained Spanish-speaking clinical staff, and barriers to recruitment and retention of this population. To encourage similar research, strategies are described that were developed by the study team to meet these challenges. PMID:17612825

  13. From Controlled Trial to Community Adoption: The Multisite Translational Community Trial

    PubMed Central

    Murimi, Mary; Gonzalez, Anjelica; Njike, Valentine; Green, Lawrence W.

    2011-01-01

    Methods for translating the findings of controlled trials, such as the Diabetes Prevention Program, into real-world community application have not been clearly defined. A standardized research methodology for making and evaluating such a transition is needed. We introduce the multisite translational community trial (mTCT) as the research analog to the multisite randomized controlled trial. The mTCT is adapted to incorporate the principles and practices of community-based participatory research and the increased relevance and generalizability gained from diverse community settings. The mTCT is a tool designed to bridge the gap between what a clinical trial demonstrates can work in principle and what is needed to make it workable and effective in real-world settings. Its utility could be put to the test, in particular with practice-based research networks such as the Prevention Research Centers. PMID:21680935

  14. Spectroscopic Survey of Cool Stars

    NASA Astrophysics Data System (ADS)

    Linsky, J.

    This program will obtain far-UV spectra of cool stars that span a broad range of spectral type and luminosity class. It is our intention to obtain these spectra early in the FUSE program and to provide the spectra quickly to the user community in order to guide potential guest investigators in designing their observing programs. The specific science objectives include: (1) studying transition region dynamics (winds and downflows), (2) modeling the thermal structure of transition regions, (3) measuring electron densities, (4) search for low temperature coronae, (5) studying molecular excitation and fluorescence processes, and (6) inferring how the transition regions of spectroscopic binary systems differ from those of single stars.

  15. MASCARA: the multi-site all-sky CAameRA: concept and first results

    NASA Astrophysics Data System (ADS)

    Lesage, A.-L.; Spronck, J. F. P.; Stuik, R.; Bettonvil, F.; Pollaco, D.; Snellen, I. A. G.

    2014-07-01

    MASCARA, the Multi-site All-Sky CAmeRA, will consist of several fully-automated stations distributed across the globe. Its goal is to find exoplanets transiting the brightest stars, in the mV = 4 to 8 magnitude range, currently probed neither by space- nor by ground-based surveys. The nearby transiting planet systems that MASCARA is expected to discover will be key targets for future detailed planet atmosphere observations. The target population for MASCARA consists mostly of hot Jupiters. The main requirement set on MASCARA to detect these planets around stars down to magnitude 8 is to reach a minimum Signal-to-Noise Ratio of 100 within one hour of observation. Each MASCARA station consists of five low-noise off-the-shelf full-frame CCD cameras, fitted with standard Canon 24 mm , f/1.4 lenses, monitoring the near-entire sky down to magnitude 8 at that location. Measurements have demonstrated that the required Signal-to-Noise Ratio of 100, can be achieved in less than thirty minutes. MASCARA aims at deploying several stations world-wide to provide a nearly continuous coverage of the dark sky, at sub-minute cadence. While at the faint end MASCARA is limited mainly by photon noise, at the bright end scintillation and red noise become the limiting factors. Instrumental noise sources are reduced by placing the cameras in a fixed orientation and in a temperature controlled environment. By defocusing and allowing stars to drift over the detector, the impact of pixel-to-pixel variations on the photometry are minimized, while taking exposures at fixed sidereal times allows accurate cross-calibration of consecutive nights. The exposure time of 6.4 seconds gives rise to a high data acquisition rate of a MASCARA station, around 500GB per night. In order to minimize data transport and data storage requirements, the raw images are reduced to produce accurate light curves in nearly real time. The first MASCARA station will be integrated on La Palma during the summer of 2014

  16. Multisite organic-inorganic hybrid catalysts for the direct sustainable synthesis of GABAergic drugs.

    PubMed

    Leyva-Pérez, Antonio; García-García, Pilar; Corma, Avelino

    2014-08-11

    Multisite organic-inorganic hybrid catalysts have been prepared and applied in a new general, practical, and sustainable synthetic procedure toward industrially relevant GABA derivatives. The domino sequence is composed of seven chemical transformations which are performed in two one-pot reactions. The method produces both enantiomeric forms of the product in high enantiopurity as well as the racemate in good yields after a single column purification step. This protocol highlights major process intensification, catalyst recyclability, and low waste generation.

  17. Multi-level assessment protocol (MAP) for adoption in multi-site clinical trials

    PubMed Central

    Guydish, J.; Manser, S.T.; Jessup, M.; Tajima, B.; Sears, C.; Montini, T.

    2010-01-01

    The National Institute on Drug Abuse (NIDA) Clinical Trials Network (CTN) is intended to test promising drug abuse treatment models in multi-site clinical trials, and to support adoption of new interventions into clinical practice. Using qualitative research methods we asked: How might the technology of multi-site clinical trials be modified to better support adoption of tested interventions? A total of 42 participants, representing 8 organizational levels ranging from clinic staff to clinical trial leaders, were interviewed about their role in the clinical trial, its interactions with clinics, and intervention adoption. Among eight clinics participating in the clinical trial, we found adoption of the tested intervention in one clinic only. In analysis of interview data we identified four conceptual themes which are likely to affect adoption and may be informative in future multi-site clinical trials. We offer the conclusion that planning for adoption in the early stages of protocol development will better serve the aim of integrating new interventions into practice. PMID:20890376

  18. Copula-based method for multisite monthly and daily streamflow simulation

    NASA Astrophysics Data System (ADS)

    Chen, Lu; Singh, Vijay P.; Guo, Shenglian; Zhou, Jianzhong; Zhang, Junhong

    2015-09-01

    Multisite stochastic simulation of streamflow sequences is needed for water resources planning and management. In this study, a new copula-based method is proposed for generating long-term multisite monthly and daily streamflow data. A multivariate copula, which is established based on bivariate copulas and conditional probability distributions, is employed to describe temporal dependences (single site) and spatial dependences (between sites). Monthly or daily streamflows at multiple sites are then generated by sampling from the conditional copula. Three tributaries of Colorado River and the upper Yangtze River are selected to evaluate the proposed methodology. Results show that the generated data at both higher and lower time scales can capture the distribution properties of the single site and preserve the spatial correlation of streamflows at different locations. The main advantage of the method is that the trivairate copula can be established using three bivariate copulas and the model parameters can be easily estimated using the Kendall tau rank correlation coefficient, which makes it possible to generate daily streamflow data. The method provides a new tool for multisite stochastic simulation.

  19. Copula-based method for Multisite Monthly and Daily Streamflow Simulation

    NASA Astrophysics Data System (ADS)

    Chen, L.; Dai, M.; Singh, V. P.; Guo, S.

    2014-12-01

    Multisite stochastic simulation of streamflow sequences is needed for water resources planning and management. In this study, a new copula-based method is proposed for generating long-term multisite monthly and daily streamflow data. A multivariate copula, which is established based on bivariate copulas and conditional probability distributions, is employed to describe temporal dependences (single site) and spatial dependences (between sites). Monthly or daily streamflows at multiple sites are then generated by sampling from the conditional copula. Three tributaries of Colorado River and the upper Yangtze River are selected to evaluate the proposed methodology. Results show that the generated data at both higher and lower time scales can capture the distribution properties of the single site and preserve the spatial correlation of streamflows at different locations. The main advantage of the method is that the model parameters can be easily estimated using Kendall tau rank correlation coefficient, which makes it possible to generate daily streamflow data. The method provides a new tool for multisite stochastic simulation.

  20. Progress in centralised ethics review processes: Implications for multi-site health evaluations.

    PubMed

    Prosser, Brenton; Davey, Rachel; Gibson, Diane

    2015-04-01

    Increasingly, public sector programmes respond to complex social problems that intersect specific fields and individual disciplines. Such responses result in multi-site initiatives that can span nations, jurisdictions, sectors and organisations. The rigorous evaluation of public sector programmes is now a baseline expectation. For evaluations of large and complex multi-site programme initiatives, the processes of ethics review can present a significant challenge. However in recent years, there have been new developments in centralised ethics review processes in many nations. This paper provides the case study of an evaluation of a national, inter-jurisdictional, cross-sector, aged care health initiative and its encounters with Australian centralised ethics review processes. Specifically, the paper considers progress against the key themes of a previous five-year, five nation study (Fitzgerald and Phillips, 2006), which found that centralised ethics review processes would save time, money and effort, as well as contribute to more equitable workloads for researchers and evaluators. The paper concludes with insights for those charged with refining centralised ethics review processes, as well as recommendations for future evaluators of complex multi-site programme initiatives.

  1. Fundamental spectroscopic studies of carbenes and hydrocarbon radicals

    SciTech Connect

    Gottlieb, C.A.; Thaddeus, P.

    1993-12-01

    Highly reactive carbenes and carbon-chain radicals are studied at millimeter wavelengths by observing their rotational spectra. The purpose is to provide definitive spectroscopic identification, accurate spectroscopic constants in the lowest vibrational states, and reliable structures of the key intermediates in reactions leading to aromatic hydrocarbons and soot particles in combustion.

  2. MultiSite Gateway-Compatible Cell Type-Specific Gene-Inducible System for Plants1[OPEN

    PubMed Central

    Siligato, Riccardo; Wang, Xin; Yadav, Shri Ram; Lehesranta, Satu; Ma, Guojie; Ursache, Robertas; Sevilem, Iris; Zhang, Jing; Gorte, Maartje; Prasad, Kalika; Heidstra, Renze

    2016-01-01

    A powerful method to study gene function is expression or overexpression in an inducible, cell type-specific system followed by observation of consequent phenotypic changes and visualization of linked reporters in the target tissue. Multiple inducible gene overexpression systems have been developed for plants, but very few of these combine plant selection markers, control of expression domains, access to multiple promoters and protein fusion reporters, chemical induction, and high-throughput cloning capabilities. Here, we introduce a MultiSite Gateway-compatible inducible system for Arabidopsis (Arabidopsis thaliana) plants that provides the capability to generate such constructs in a single cloning step. The system is based on the tightly controlled, estrogen-inducible XVE system. We demonstrate that the transformants generated with this system exhibit the expected cell type-specific expression, similar to what is observed with constitutively expressed native promoters. With this new system, cloning of inducible constructs is no longer limited to a few special cases but can be used as a standard approach when gene function is studied. In addition, we present a set of entry clones consisting of histochemical and fluorescent reporter variants designed for gene and promoter expression studies. PMID:26644504

  3. Multisite, open-label, prospective trial of lamotrigine for geriatric bipolar depression: a preliminary report

    PubMed Central

    Sajatovic, Martha; Gildengers, Ariel; Jurdi, Rayan K Al; Gyulai, Laszlo; Cassidy, Kristin A; Greenberg, Rebecca L; Bruce, Martha L; Mulsant, Benoit H; Have, Thomas Ten; Young, Robert C

    2013-01-01

    Aims This is a multisite, 12-week, open-label trial of lamotrigine augmentation in 57 older adults (≥ 60 years; mean ± SD age = 66.5 ± 6.7 years) with either type I or type II bipolar depression. Methods Primary outcome measure was change from baseline on the Montgomery-Åsberg Depression Rating Scale (MADRS). Secondary outcome measures included Hamilton Depression Rating Scale (HAM-D), Clinical Global Impression-Bipolar version (CGI-BP), and the WHO-Disability Assessment Schedule II (WHO-DAS II). The Udvalg for Kliniske Undersøgelser (UKU) was used to assess side effects. Results A total of 77.2% of the study subjects had bipolar I disorder. The mean (SD) lamotrigine dose was 150.9 (68.5) mg/day. There was significant improvement in the MADRS, HAM-D, CGI-BP, and in most domains on the WHO-DAS II. For patients for whom final MADRS score was available: 31 (57.4%) met remission criteria and 35 (64.8%) met response criteria. There were 19/57 (33.3%) who dropped out of the study prematurely, with 6 dropouts due to adverse events (4 cases of rash, 1 manic switch, and 1 hyponatremia). Two cases of rash were possibly drug related and were resolved with drug discontinuation. The most common UKU adverse effects were reduced sleep duration (n = 14, 24.6%), weight loss (n = 12, 21.1%), increased dream activity (n = 12, 21.1%), polyuria/polydipsia (n = 11, 19.3%), weight gain (n = 9, 15.8%), diminished sexual desire (n = 9, 15.8%), increased sleep (n = 9, 15.8%), lassitude/fatigue (n = 8, 14%), and unsteady gait (n = 8, 14%). No significant changes in electrocardiogram or laboratory tests were observed. Conclusions In bipolar depressed elders, lamotrigine was associated with improvement in depression, psychopathology, and functional status. There was a moderate number of adverse events, although relationship of adverse events (particularly falls) to study medication could not be clearly determined in this uncontrolled trial. Controlled studies are needed to further

  4. MAMA Spectroscopic Throughputs

    NASA Astrophysics Data System (ADS)

    Lennon, Daniel

    2009-07-01

    This activity sets new baseline post-SM4 sensitivity/throughput measurements for all the STIS/MAMA spectroscopic modes, and establishes if there changes with respect to perfomance prior to the LVPS failure. It also checks the NUV focus of STIS and its dependence on wavelength.

  5. Asiago spectroscopic classification of SN 2016fmt

    NASA Astrophysics Data System (ADS)

    Nascimbeni, V.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Ochner, P.; Pastorello, A.; Terreran, G.; Tomasella, L.; Turatto, M.

    2016-08-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic observation of AT 2016fmt discovered by Fabrizio Ciabattari of the Italian Supernova Search Project (ISSP) in NGC 606, who reports a discovery magnitude of 17.8 on UT 2016-08-28 02:52:48.

  6. Spectroscopic mode identification in gamma Doradus stars

    NASA Astrophysics Data System (ADS)

    Rylvia Pollard, Karen

    2015-08-01

    The MUSICIAN programme at the University of Canterbury has been successfully identifying frequencies and pulsation modes in many gamma Doradus stars using hundreds of precise, high resolution spectroscopic observations. This paper describes some of these frequency and mode identifications and the emerging patterns of the programme.

  7. Reduced Frontoparietal Activity in Schizophrenia Is Linked to a Specific Deficit in Goal Maintenance: A Multisite Functional Imaging Study.

    PubMed

    Poppe, Andrew B; Barch, Deanna M; Carter, Cameron S; Gold, James M; Ragland, John Daniel; Silverstein, Steven M; MacDonald, Angus W

    2016-09-01

    Patients with schizophrenia (SZ) previously demonstrated specific deficits in an executive function known as goal maintenance, associated with reduced middle frontal gyrus (MFG) activity. This study aimed to validate a new tool-the Dot Pattern Expectancy (DPX) task-developed to facilitate multisite imaging studies of goal maintenance deficits in SZ or other disorders. Additionally, it sought to arrive at recommendations for scan length for future studies using the DPX. Forty-seven SZ and 56 healthy controls (HC) performed the DPX in 3-Tesla functional magnetic resonance imaging (fMRI) scanners at 5 sites. Group differences in DPX-related activity were examined with whole brain voxelwise analyses. SZs showed the hypothesized specific performance deficits with as little as 1 block of data. Reduced activity in SZ compared with HC was observed in bilateral frontal pole/MFG, as well as left posterior parietal lobe. Efficiency analyses found significant group differences in activity using 18 minutes of scan data but not 12 minutes. Several behavioral and imaging findings from the goal maintenance literature were robustly replicated despite the use of different scanners at different sites. We did not replicate a previous correlation with disorganization symptoms among patients. Results were consistent with an executive/attention network dysfunction in the higher levels of a cascading executive system responsible for goal maintenance. Finally, efficiency analyses found that 18 minutes of scanning during the DPX task is sufficient to detect group differences with a similar sample size.

  8. Spectroscopic Low Coherence Interferometry

    NASA Astrophysics Data System (ADS)

    Bosschaart, Nienke; van Leeuwen, T. G.; Aalders, Maurice C.; Hermann, Boris; Drexler, Wolfgang; Faber, Dirk J.

    Low-coherence interferometry (LCI) allows high-resolution volumetric imaging of tissue morphology and provides localized optical properties that can be related to the physiological status of tissue. This chapter discusses the combination of spatial and spectroscopic information by means of spectroscopic OCT (sOCT) and low-coherence spectroscopy (LCS). We describe the theory behind these modalities for the assessment of spatially resolved optical absorption and (back)scattering coefficient spectra. These spectra can be used for the highly localized quantification of chromophore concentrations and assessment of tissue organization on (sub)cellular scales. This leads to a wealth of potential clinical applications, ranging from neonatology for the determination of billibrubin concentrations, to oncology for the optical assessment of the aggressiveness of a cancerous lesion.

  9. Multivariate real-time assessment of droughts via copula-based multi-site Hazard Trajectories and Fans

    NASA Astrophysics Data System (ADS)

    Salvadori, G.; De Michele, C.

    2015-07-01

    Droughts, like floods, represent the most dangerous, and costly, water cycle expressions, with huge impacts on society and built environment. Droughts are events occurring over a certain region, lasting several weeks or months, and involving multiple variables: thus, a multivariate, multi-site, approach is most appropriate for their statistical characterization. In this methodological work, hydrological droughts are considered, and a multivariate approach is proposed, by regarding as relevant variables the duration and the average intensity. A multivariate, multi-site, frequency analysis is presented, based on the Theory of Copulas and the joint Survival Kendall's Return Periods, by investigating the historical drought episodes occurred at five main river sections of the Po river (Northern Italy), the most important Italian basin. The tool of Dynamic Return Period is used, and the new concepts of Hazard Trajectories and Fans are introduced, in order to provide useful indications for a valuable multi-site real-time assessment of droughts.

  10. Spectroscopic Classifications of Optical Transients with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Miller, J.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-04-01

    We report the following classifications of optical transients from spectroscopic observations with the KOSMOS on the Mayall telescope. Targets were supplied by the Pan-STARRS Survey for Transients (PSST).

  11. Spectroscopic Classifications of AT2016esx with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Kilpatrick, C. D.; Siebert, M. R.; Coulter, D. A.; Foley, R. J.; Pan, Y.-C.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    We report a classification of ASASSN-16io = AT2016esx from spectroscopic observations with KOSMOS on the KPNO Mayall 4-m telescope. Targets were supplied by the All-Sky Automated Survey for Supernovae (ASAS-SN).

  12. Spectroscopic Classifications of Optical Transients with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Kilpatrick, C. D.; Siebert, M. R.; Foley, R. J.; Pan, Y.-C.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    We report the following classifications of optical transients from spectroscopic observations with KOSMOS on the KPNO Mayall 4-m telescope. Targets were supplied by Shunsuke Nagata, POSS, and ASAS-SN.

  13. Process evaluation of the Hunter Illawarra Kids Challenge Using Parent Support study: a multisite randomized controlled trial for the management of child obesity.

    PubMed

    Jones, Rachel A; Warren, Janet M; Okely, Anthony D; Collins, Clare E; Morgan, Philip J; Cliff, Dylan P; Burrows, Tracy; Cleary, Jane; Baur, Louise A

    2010-11-01

    The purposes of this article are to (a) outline findings from secondary or process outcome data of the Hunter Illawarra Kids Challenge Using Parent Support (HIKCUPS) study and (b) inform the design and development of future research interventions and practice in the management of child obesity. Data were collected by means of facilitator evaluations, independent session observation, attendance records, and parent questionnaires. Internal validity and reliability of the program delivery were high. All parents reported positive changes in their children as a result of the physical activity program, the dietary modification program, or both. Most participants completed the home activities, but more than half reported that finding time to do them was problematic. Facilitator review indicated that future programs should specifically cater to children of similar age or same sex, allow adequate time for explanation of complex nutritional concepts, and use intrinsic motivators for participants. Recommendations for future interventions, specifically the implementation of subsequent HIKCUPS or other multisite effectiveness studies, are detailed.

  14. A Hybrid Approach for Precipitation Simulation Using the Multi-site Neyman-Scott Rainfall Pulse Model and the Analog Method

    NASA Astrophysics Data System (ADS)

    Kaheil, Y. H.; Lohmann, D.; Goteti, G.; Katz, B. G.; RMS Model Dev Team

    2011-12-01

    The Multi-site Neyman-Scott Rainfall Pulse model (MNSRP) was previously implemented in many studies over different climate zones and is known for its capability to accurately capture the statistical and the geostatistical properties of the precipitation process up to the third moment, which is a key factor in extreme precipitation analysis. However, due to the purely stochastic nature of the model, larger spatial precipitation patterns cannot be captured, especially when the model is implemented over large regions. The Analog Method (AM) uses observed precipitation EOFs to accurately simulate precipitation spatially. The quality of the AM simulations suffers in arid and semi-arid regions where the statistical properties of the precipitation process are harder to capture. The Hybrid Approach (HA) uses the AM simulations to locally rank the MNSRP simulations for each month. Case studies in different climatic regions in the US show that the new approach compares favorably to each individual model.

  15. Reliability of an fMRI Paradigm for Emotional Processing in a Multisite Longitudinal Study

    PubMed Central

    Gee, Dylan G.; McEwen, Sarah C.; Forsyth, Jennifer K.; Haut, Kristen M.; Bearden, Carrie E.; Addington, Jean; Goodyear, Bradley; Cadenhead, Kristin S.; Mirzakhanian, Heline; Cornblatt, Barbara A.; Olvet, Doreen; Mathalon, Daniel H.; McGlashan, Thomas H.; Perkins, Diana O.; Belger, Aysenil; Seidman, Larry J.; Thermenos, Heidi; Tsuang, Ming T.; van Erp, Theo G.M.; Walker, Elaine F.; Hamann, Stephan; Woods, Scott W.; Constable, Todd; Cannon, Tyrone D.

    2015-01-01

    Multisite neuroimaging studies can facilitate the investigation of brain-related changes in many contexts, including patient groups that are relatively rare in the general population. Though multisite studies have characterized the reliability of brain activation during working memory and motor functional magnetic resonance imaging tasks, emotion processing tasks, pertinent to many clinical populations, remain less explored. A traveling participants study was conducted with eight healthy volunteers scanned twice on consecutive days at each of the eight North American Longitudinal Prodrome Study sites. Tests derived from generalizability theory showed excellent reliability in the amygdala (Eρ2=0.82), inferior frontal gyrus (IFG;Eρ2=0.83), anterior cingulate cortex (ACC;Eρ2=0.76), insula (Eρ2=0.85), and fusiform gyrus (Eρ2=0.91) for maximum activation and fair to excellent reliability in the amygdala (Eρ2=0.44), IFG (Eρ2=0.48), ACC (Eρ2=0.55), insula (Eρ2=0.42), and fusiform gyrus (Eρ2=0.83) for mean activation across sites and test days. For the amygdala, habituation (Eρ2=0.71) was more stable than mean activation. In a second investigation, data from 111 healthy individuals across sites were aggregated in a voxelwise, quantitative meta-analysis. When compared with a mixed effects model controlling for site, both approaches identified robust activation in regions consistent with expected results based on prior single-site research. Overall, regions central to emotion processing showed strong reliability in the traveling participants study and robust activation in the aggregation study. These results support the reliability of blood oxygen level-dependent signal in emotion processing areas across different sites and scanners and may inform future efforts to increase efficiency and enhance knowledge of rare conditions in the population through multisite neuroimaging paradigms. PMID:25821147

  16. Provider perceptions of knowledge exchange and communication in a multisite family health team

    PubMed Central

    Slater, Morgan; Nicholas, Emily; Leung, Fok-Han; Lofters, Aisha

    2016-01-01

    Abstract Objective To describe providers’ self-reported knowledge and use of family health team (FHT) services and to explore attitudes and perspectives about communication issues among health care professionals active within a large multisite FHT. Design Electronic questionnaire. Setting A multisite FHT in Toronto, Ont. Participants Health care professionals active within the FHT (N = 90). Main outcome measures The survey captured demographic characteristics, including the respondents’ roles and experience; knowledge about services available within the FHT; use of services; and perceived communication issues within the FHT. Results Forty-six health care professionals participated (51% response rate). While respondents were highly aware of the clinical resources and services offered at their own site of practice (95% agreed or strongly agreed), only 54% were aware of services offered at other sites within the FHT. Internal referrals for certain specialty services were high (ie, methadone management, obstetric care, intrauterine device insertion, and psychiatry), but less than 50% of other referrals (ie, sports medicine, joint injections, or tropical medicine) were to physicians within the FHT, despite physicians within the FHT offering services in these areas of expertise. Only 60% of respondents believed that patients had equal access to all of the services within the FHT, and 42% agreed or strongly agreed that patients were unlikely to travel between sites to access services. Roughly one-quarter of respondents believed that physicians were unlikely to refer patients to another site within the FHT to receive health care services. Most respondents agreed that the geographic distribution of the sites negatively affected communication within the FHT (68% agreed or strongly agreed). Conclusion Geographic dispersion of team members in a multisite FHT had a negative effect on provider knowledge of available services, perceived patient access to services, and

  17. Approaches and Recommendations for Simulating Extreme Precipitation Years in Multi-site Experiments

    NASA Astrophysics Data System (ADS)

    Knapp, A.; Collins, S. L.; Dukes, J.; Loik, M. E.; Phillips, R.; Sala, O. E.; Smith, M.

    2015-12-01

    Worldwide, human activities are exposing all ecosystems to increases in atmospheric CO2, N and temperature. Precipitation also is being altered globally, but increases in precipitation variability and extremes are expected to have greater impacts on ecosystem function than changes in means. Determining how and why ecosystems differ in their sensitivity to precipitation extremes (i.e., drought) is key to forecasting future ecosystem structure and function at the global scale. Coordinated multi-site experiments can be invaluable for assessing differential sensitivity of ecosystems (deserts, grasslands, forests, etc.) to precipitation extremes. However, determining treatment levels in these experiments presents unique problems because extremes in precipitation are defined statistically, based on historical context, and thus can differ dramatically among sites. Therefore, while multi-site experiments with fixed treatment levels may be appropriate for assessing ecosystem sensitivity to CO2 or warming, they may provide less mechanistic insight for studying extremes. We propose that for multi-site experiments focused on variability and extremes, the amount of precipitation removed or added to impose precipitation extremes should be site-specific (not fixed across sites) and matched to the historical climate record. Further, because extreme wet and dry years differ from each other in other attributes (event size, number of events, consecutive dry days, etc.) treatments should incorporate realistic alterations in these precipitation attributes as well. We show that for most ecosystem types globally, experimental infrastructure that passively reduces each rainfall event can realistically simulate drought, with the addition of a few large precipitation events realistically simulating extreme wet years. Thus, while treatment levels required to impose extreme precipitation years should vary among ecosystems, alterations in precipitation attributes can be imposed uniformly.

  18. Adsorption preference reversal phenomenon from multisite-occupancy theory for two-dimensional lattices

    NASA Astrophysics Data System (ADS)

    Matoz-Fernandez, D. A.; Ramirez-Pastor, A. J.

    2014-08-01

    The statistical thermodynamics of polyatomic species mixtures adsorbed on two-dimensional substrates was developed on a generalization in the spirit of the lattice-gas model and the classical Guggenheim-DiMarzio approximation. In this scheme, the coverage and temperature dependence of the Helmholtz free energy and chemical potential are given. The formalism leads to the exact statistical thermodynamics of binary mixtures adsorbed in one dimension, provides a close approximation for two-dimensional systems accounting multisite occupancy and allows to discuss the dimensionality and lattice structure effects on the known phenomenon of adsorption preference reversal.

  19. The Benefits and Challenges of Preconsent in a Multisite, Pediatric Sickle Cell Intervention Trial.

    PubMed

    Nimmer, Mark; Czachor, Jason; Turner, Laura; Thomas, Bobbe; Woodford, Ashley L; Carpenter, Karli; Gonzalez, Victor; Liem, Robert I; Ellison, Angela; Casper, T Charles; Brousseau, David C

    2016-09-01

    Enrollment of patients in sickle cell intervention trials has been challenging due to difficulty in obtaining consent from a legal guardian and lack of collaboration between emergency medicine and hematology. We utilized education and preconsent in a pediatric multisite sickle cell intervention trial to overcome these challenges. Overall, 48 patients were enrolled after being preconsented. Variable Institutional Review Board policies related to preconsent validity and its allowable duration decreased the advantages of preconsent at some sites. The utility of preconsent for future intervention trials largely depends on local Institutional Review Board policies. Preeducation may also benefit the consent process, regardless of site differences. PMID:27081930

  20. The 2003-2004 multisite photometric campaign for the β Cephei and eclipsing star 16 (EN) Lacertae with an appendix on 2 Andromedae, the variable comparison star

    NASA Astrophysics Data System (ADS)

    Jerzykiewicz, M.; Handler, G.; Daszyńska-Daszkiewicz, J.; Pigulski, A.; Poretti, E.; Rodríguez, E.; Amado, P. J.; Kołaczkowski, Z.; Uytterhoeven, K.; Dorokhova, T. N.; Dorokhov, N. I.; Lorenz, D.; Zsuffa, D.; Kim, S.-L.; Bourge, P.-O.; Acke, B.; De Ridder, J.; Verhoelst, T.; Drummond, R.; Movchan, A. I.; Lee, J.-A.; Stȩślicki, M.; Molenda-Żakowicz, J.; Garrido, R.; Kim, S.-H.; Michalska, G.; Paparó, M.; Antoci, V.; Aerts, C.

    2015-11-01

    A multisite photometric campaign for the β Cephei and eclipsing variable 16 Lacertae is reported. 749 h of high-quality differential photoelectric Strömgren, Johnson and Geneva time series photometry were obtained with 10 telescopes during 185 nights. After removing the pulsation contribution, an attempt was made to solve the resulting eclipse light curve by means of the computer program EBOP. Although a unique solution was not obtained, the range of solutions could be constrained by comparing computed positions of the secondary component in the Hertzsprung-Russell diagram with evolutionary tracks. For three high-amplitude pulsation modes, the uvy and the Geneva UBG amplitude ratios are derived and compared with the theoretical ones for spherical-harmonic degrees ℓ ≤ 4. The highest degree, ℓ = 4, is shown to be incompatible with the observations. One mode is found to be radial, one is ℓ = 1, while in the remaining case ℓ = 2 or 3. The present multisite observations are combined with the archival photometry in order to investigate the long-term variation of the amplitudes and phases of the three high-amplitude pulsation modes. The radial mode shows a non-sinusoidal variation on a time-scale of 73 yr. The ℓ = 1 mode is a triplet with unequal frequency spacing, giving rise to two beat-periods, 720.7 d and 29.1 yr. The amplitude and phase of the ℓ = 2 or 3 mode vary on time-scales of 380.5 d and 43 yr. The light variation of 2 And, one of the comparison stars, is discussed in the appendix.

  1. Mauna Kea Observatory infrared observations

    NASA Technical Reports Server (NTRS)

    Jefferies, J. T.

    1974-01-01

    Galactic and solar system infrared observations are reported using a broad variety of radiometric and spectroscopic instrumentation. Infrared programs and papers published during this period are listed.

  2. Observations of active chromosphere stars

    NASA Technical Reports Server (NTRS)

    Africano, J. L.; Klimke, A.; Stencel, R. E.; Noah, P. V.; Bopp, B. W.

    1983-01-01

    It is pointed out that spectroscopic signatures of stellar chromospheric activity are readily observable. The present study is concerned with new photometric and spectroscopic observations of active-chromosphere RS CVn, BY Dra, and FK Com stars. Attention is given to the first results of a synoptic monitoring program of many active chromosphere stars. During the time from 1980 to 1982, photometric and spectroscopic observations of 10 known or suspected active-chromosphere objects were made. The results regarding the individual stars are discussed. Seven stars observed with the International Ultraviolet Explorer (IUE) are all spectroscopic binaries.

  3. Multifunction Imaging and Spectroscopic Instrument

    NASA Technical Reports Server (NTRS)

    Mouroulis, Pantazis

    2004-01-01

    A proposed optoelectronic instrument would perform several different spectroscopic and imaging functions that, heretofore, have been performed by separate instruments. The functions would be reflectance, fluorescence, and Raman spectroscopies; variable-color confocal imaging at two different resolutions; and wide-field color imaging. The instrument was conceived for use in examination of minerals on remote planets. It could also be used on Earth to characterize material specimens. The conceptual design of the instrument emphasizes compactness and economy, to be achieved largely through sharing of components among subsystems that perform different imaging and spectrometric functions. The input optics for the various functions would be mounted in a single optical head. With the exception of a targeting lens, the input optics would all be aimed at the same spot on a specimen, thereby both (1) eliminating the need to reposition the specimen to perform different imaging and/or spectroscopic observations and (2) ensuring that data from such observations can be correlated with respect to known positions on the specimen. The figure schematically depicts the principal components and subsystems of the instrument. The targeting lens would collect light into a multimode optical fiber, which would guide the light through a fiber-selection switch to a reflection/ fluorescence spectrometer. The switch would have four positions, enabling selection of spectrometer input from the targeting lens, from either of one or two multimode optical fibers coming from a reflectance/fluorescence- microspectrometer optical head, or from a dark calibration position (no fiber). The switch would be the only moving part within the instrument.

  4. Coarse-graining polymer solutions: A critical appraisal of single- and multi-site models

    NASA Astrophysics Data System (ADS)

    D'Adamo, G.; Menichetti, R.; Pelissetto, A.; Pierleoni, C.

    2015-09-01

    We critically discuss and review the general ideas behind single- and multi-site coarse-grained (CG) models as applied to macromolecular solutions in the dilute and semi-dilute regime. We first consider single-site models with zero-density and density-dependent pair potentials. We highlight advantages and limitations of each option in reproducing the thermodynamic behavior and the large-scale structure of the underlying reference model. As a case study we consider solutions of linear homopolymers in a solvent of variable quality. Secondly, we extend the discussion to multi-component systems presenting, as a test case, results for mixtures of colloids and polymers. Specifically, we found the CG model with zero-density potentials to be unable to predict fluid-fluid demixing in a reasonable range of densities for mixtures of colloids and polymers of equal size. For larger colloids, the polymer volume fractions at which phase separation occurs are largely overestimated. CG models with density-dependent potentials are somewhat less accurate than models with zero-density potentials in reproducing the thermodynamics of the system and, although they present a phase separation, they significantly underestimate the polymer volume fractions along the binodal. Finally, we discuss a general multi-site strategy, which is thermodynamically consistent and fully transferable with the number of sites, and that allows us to overcome most of the limitations discussed for single-site models.

  5. A novel high channel-count system for acute multisite neuronal recordings.

    PubMed

    Hofmann, Ulrich G; Folkers, Andre; Mösch, Florian; Malina, Thomas; Menne, Kerstin M L; Biella, Gerardo; Fagerstedt, Patriq; De Schutter, Erik; Jensen, Winnie; Yoshida, Ken; Hoehl, Dirk; Thomas, Uwe; Kindlundh, Maria G; Norlin, Peter; de Curtis, Marco

    2006-08-01

    Multisite recording represents a suitable condition to study microphysiology and network interactions in the central nervous system and, therefore, to understand brain functions. Several different materials and array configurations have been proposed for the development of new probes utilized to record brain activity from experimental animal models. We describe new multisite silicon probes that broaden the currently available application base for neuroscientists. The array arrangement of the probes recording sites was extended to increase their spatial resolution. Probes were integrated with a newly developed electronic hardware and novel software for advanced real-time processing and analysis. The new system, based on 32- and 64-electrode silicon probes, proved very valuable to record field potentials and single unit activity from the olfactory-limbic cortex of the in vitro isolated guinea-pig brain preparation and to acutely record unit activity at multiple sites from the cerebellar cortex in vivo. The potential advantages of the new system in comparison to the currently available technology are discussed.

  6. A multi-site dose ranging study of nalmefene in the treatment of alcohol dependence.

    PubMed

    Anton, Raymond F; Pettinati, Helen; Zweben, Allen; Kranzler, Henry R; Johnson, Bankole; Bohn, Michael J; McCaul, Mary E; Anthenelli, Robert; Salloum, Ihsan; Galloway, Gantt; Garbutt, James; Swift, Robert; Gastfriend, David; Kallio, Antero; Karhuvaara, Sakari

    2004-08-01

    The opiate antagonist nalmefene has been shown in 2 single-site studies to reduce alcohol consumption and relapse drinking in alcohol-dependent individuals. This safety and preliminary multisite efficacy study evaluated 3 doses of nalmefene (5, 20, or 40 mg) in a double-blind comparison to placebo over a 12-week treatment period in 270 recently abstinent outpatient alcohol-dependent individuals. Participants concomitantly received 4 sessions of a motivational enhancement therapy (with a medication compliance component) delivered from trained counselors. Although more subjects in the active medication groups terminated the study early secondary to adverse events, the rates did not differ significantly from that of placebo. The 20-mg/d group experienced more insomnia, dizziness, and confusion, while the 5-mg group also had more dizziness and the 40-mg group had more nausea than the placebo group. Most of these symptoms were mild and improved over time. Although all subjects had a reduction in heavy drinking days, craving, gamma-glutamyl transferase, and carbohydrate-deficient transferrin concentrations over the course of the study, there was no difference between the active medication and placebo groups on these measures. The time to first heavy drinking day was also not significantly different between the placebo and the active treatment groups. This relatively small multisite trial showed that nalmefene was reasonably well tolerated in recently abstinent alcoholics. However, possibly because of variation among the sites or the comparatively small sample size, there was no evidence of superior efficacy outcomes with nalmefene treatment.

  7. Combinatorial profiling of chromatin-binding modules reveals multi-site discrimination

    PubMed Central

    Garske, Adam L.; Oliver, Samuel S.; Wagner, Elise K.; Musselman, Catherine A.; LeRoy, Gary; Garcia, Benjamin A.; Kutateladze, Tatiana G.; Denu, John M.

    2009-01-01

    Specific interactions between post-translational modifications (PTMs) and chromatin-binding proteins are central to the idea of a ‘histone code’. Here, a 5000-member, PTM-randomized, combinatorial peptide library based on the N-terminus of histone H3 was utilized to interrogate multi-site specificity of six chromatin-binding modules, which read the methylation status of K4. We found that T3 phosphorylation, R2 methylation, and T6 phosphorylation are critical additional PTMs that modulate the ability to recognize and bind histone H3. Notably, phosphorylation of T6 yielded the most varied effect on protein binding, suggesting an important regulatory mechanism for readers of the H3 tail. Mass spectrometry and antibody-based evidence indicate that this previously uncharacterized modification exists on native H3, and NMR analysis of ING2 revealed the structural basis for discrimination. These investigations reveal a continuum of binding affinities in which multi-site PTM recognition involves both switch- and rheostat-like properties, yielding graded effects that depend on the inherent ‘reader’ specificity. PMID:20190764

  8. eGEMs: Pathways to Success for Multisite Clinical Data Research.

    PubMed

    McGraw Jd, Deven C; Leiter Jd, Alice B

    2013-01-01

    There are numerous and significant challenges associated with leveraging electronic clinical data (ECD) for purposes beyond treating an individual patient and getting paid for that care. Optimizing this secondary use of clinical data is a key underpinning of many health reform goals and triggers numerous issues related to data stewardship and, more broadly, data governance. These challenges often involve legal, policy, and procedural issues related to the access, use, and disclosure of electronic health record (EHR) data for quality improvement and research. This paper contributes to the ongoing discussion of health data governance by detailing the experiences of nine multisite research initiatives across the country. The rich set of experiences from these initiatives, as well as a number of resources used by project participants to work through various challenges, are documented and collected here for others wishing to learn from their collective efforts. The paper does not attempt to catalog the full spectrum of governance issues that could potentially surface in the course of multisite research projects using ECD. Rather, the goal was to provide a snapshot in time of data-sharing challenges and navigation strategies, as well as validation that privacy-protective, legally compliant clinical data sharing across sites is currently possible. Finally, the paper also provides a foundation and framing for a broader community resource on governance-a "governance toolkit"-that will create a virtual space for the further discussion and sharing of promising practices.

  9. Flexible split-ring electrode for insect flight biasing using multisite neural stimulation.

    PubMed

    Tsang, Wei Mong; Stone, Alice L; Aldworth, Zane N; Hildebrand, John G; Daniel, Tom L; Akinwande, Akintunde Ibitayo; Voldman, Joel

    2010-07-01

    We describe a flexible multisite microelectrode for insect flight biasing using neural stimulation. The electrode is made of two layers of polyimide (PI) with gold sandwiched in between in a split-ring geometry. The split-ring design in conjunction with the flexibility of the PI allows for a simple insertion process and provides good attachment between the electrode and ventral nerve cord of the insect. Stimulation sites are located at the ends of protruding tips that are circularly distributed inside the split-ring structure. These protruding tips penetrate into the connective tissue surrounding the nerve cord. We have been able to insert the electrode into pupae of the giant sphinx moth Manduca sexta as early as seven days before the adult moth emerges, and we are able to use the multisite electrode to deliver electrical stimuli that evoke multidirectional, graded abdominal motions in both pupae and adult moths. Finally, in loosely tethered flight, we have used stimulation through the flexible microelectrodes to alter the abdominal angle, thus causing the flying moth to deviate to the left or right of its intended path.

  10. Diffusion modifies the connectivity of kinetic schemes for multisite binding and catalysis.

    PubMed

    Gopich, Irina V; Szabo, Attila

    2013-12-01

    The simplest way to describe the influence of the relative diffusion of the reactants on the time course of bimolecular reactions is to modify or renormalize the phenomenological rate constants that enter into the rate equations of conventional chemical kinetics. However, for macromolecules with multiple inequivalent reactive sites, this is no longer sufficient, even in the low concentration limit. The physical reason is that an enzyme (or a ligand) that has just modified (or dissociated from) one site can bind to a neighboring site rather than diffuse away. This process is not described by the conventional chemical kinetics, which is only valid in the limit that diffusion is fast compared with reaction. Using an exactly solvable many-particle reaction-diffusion model, we show that the influence of diffusion on the kinetics of multisite binding and catalysis can be accounted for by not only scaling the rates, but also by introducing new connections into the kinetic scheme. The rate constants that describe these new transitions or reaction channels turn out to have a transparent physical interpretation: The chemical rates are scaled by the appropriate probabilities that a pair of reactants, which are initially in contact, bind rather than diffuse apart. The theory is illustrated by application to phosphorylation of a multisite substrate.

  11. Progressive Reduction in Cortical Thickness as Psychosis Develops: A Multisite Longitudinal Neuroimaging Study of Youth at Elevated Clinical Risk

    PubMed Central

    Cannon, Tyrone D.; Chung, Yoonho; He, George; Sun, Daqiang; Jacobson, Aron; van Erp, Theo G. M.; McEwen, Sarah; Addington, Jean; Bearden, Carrie E.; Cadenhead, Kristin; Cornblatt, Barbara; Mathalon, Daniel H.; McGlashan, Thomas; Perkins, Diana; Jeffries, Clark; Seidman, Larry J.; Tsuang, Ming; Walker, Elaine; Woods, Scott W.; Heinssen, Robert

    2014-01-01

    Background Individuals at clinical high-risk (CHR) who progress to fully psychotic symptoms have been observed to show a steeper rate of cortical gray matter reduction compared with those without symptomatic progression and with healthy controls. Whether such changes reflect processes associated with the pathophysiology of schizophrenia or exposure to antipsychotic drugs is unknown. Methods In this multisite study, 274 CHR cases, including 35 who converted to psychosis, and 135 healthy comparison subjects were scanned with MRI at baseline, 12-month follow-up, and/or the point of conversion for those who developed fully psychotic symptoms. Results In a traveling subjects sub-study, we observed excellent reliability for measures of cortical thickness and subcortical volumes. Controlling for multiple comparisons throughout the brain, CHR converters showed a steeper rate of gray matter loss in right superior frontal, middle frontal, and medial orbitofrontal cortical regions, as well as a greater rate of expansion of the third ventricle, compared with CHR non-converters and healthy controls. Differential tissue loss was present among cases who had not received antipsychotic medications during the inter-scan interval and was predicted by baseline levels of an aggregate measure of pro-inflammatory cytokines in plasma. Conclusions These findings demonstrate that the brain changes are not explained by exposure to antipsychotic drugs, but likely play a role in psychosis pathophysiology. Given that the cortical changes were more pronounced among cases with briefer durations of prodromal symptoms, contributing factors may predominantly play a role in acute-onset forms of psychosis. PMID:25034946

  12. Gender Differences in Clinical Outcomes among HIV-Positive Individuals on Antiretroviral Therapy in Canada: A Multisite Cohort Study

    PubMed Central

    Cescon, Angela; Patterson, Sophie; Chan, Keith; Palmer, Alexis K.; Margolese, Shari; Burchell, Ann N.; Cooper, Curtis; Klein, Marina B.; Machouf, Nima; Montaner, Julio S. G.; Tsoukas, Chris; Hogg, Robert S.; Raboud, Janet M.; Loutfy, Mona R.

    2013-01-01

    Background Cohort data examining differences by gender in clinical responses to combination antiretroviral therapy (ART) remain inconsistent and have yet to be explored in a multi-province Canadian setting. This study investigates gender differences by injection drug use (IDU) history in virologic responses to ART and mortality. Methods Data from the Canadian Observational Cohort (CANOC) collaboration, a multisite cohort study of HIV-positive individuals initiating ART after January 1, 2000, were included. This analysis was restricted to participants with a follow-up HIV-RNA plasma viral load measure and known IDU history. Weibull hazard regression evaluated time to virologic suppression (2 consecutive measures <50 copies/mL), rebound (>1000 copies/mL after suppression), and all-cause mortality. Sensitivity analyses explored the impact of presumed ART use in pregnancy on virologic outcomes. Results At baseline, women (1120 of 5442 participants) were younger (median 36 vs. 41 years) and more frequently reported IDU history (43.5% vs. 28.8%) (both p<0.001). Irrespective of IDU history, in adjusted multivariable analyses women were significantly less likely to virologically suppress after ART initiation and were at increased risk of viral load rebound. In adjusted time to death analysis, no differences by gender were noted. After adjusting for presumed ART use in pregnancy, observed gender differences in time to virologic suppression for non-IDU, and time to virologic rebound for IDU, became insignificant. Conclusions HIV-positive women in CANOC are at heightened risk for poor clinical outcomes. Further understanding of the intersections between gender and other factors augmenting risk is needed to maximize the benefits of ART. PMID:24391803

  13. On the use of multi-algorithm, genetically adaptive multi-objective method for multi-site calibration of the SWAT model

    SciTech Connect

    Zhang, Xuesong; Srinivasan, Raghavan; Van Liew, M.

    2010-04-15

    With the availability of spatially distributed data, distributed hydrologic models are increasingly used for simulation of spatially varied hydrologic processes to understand and manage natural and human activities that affect watershed systems. Multi-objective optimization methods have been applied to calibrate distributed hydrologic models using observed data from multiple sites. As the time consumed by running these complex models is increasing substantially, selecting efficient and effective multi-objective optimization algorithms is becoming a nontrivial issue. In this study, we evaluated a multi-algorithm, genetically adaptive multi-objective method (AMALGAM) for multi-site calibration of a distributed hydrologic model—Soil and Water Assessment Tool (SWAT), and compared its performance with two widely used evolutionary multi-objective optimization (EMO) algorithms (i.e. Strength Pareto Evolutionary Algorithm 2 (SPEA2) and Non-dominated Sorted Genetic Algorithm II (NSGA-II)). In order to provide insights into each method’s overall performance, these three methods were tested in four watersheds with various characteristics. The test results indicate that the AMALGAM can consistently provide competitive or superior results compared with the other two methods. The multi-method search framework of AMALGAM, which can flexibly and adaptively utilize multiple optimization algorithms, makes it a promising tool for multi-site calibration of the distributed SWAT. For practical use of AMALGAM, it is suggested to implement this method in multiple trials with relatively small number of model runs rather than run it once with long iterations. In addition, incorporating different multiobjective optimization algorithms and multi-mode search operators into AMALGAM deserves further research.

  14. Learning "about" and "from" Variation in Program Impacts Using Multisite Trials. MDRC Working Papers on Research Methodology

    ERIC Educational Resources Information Center

    Raudenbush, Stephen W.; Bloom, Howard S.

    2015-01-01

    The present paper, which is intended for a diverse audience of evaluation researchers, applied social scientists, and research funders, provides a broad overview of the conceptual and statistical issues involved in using multisite randomized trials to learn "about" and "from" variation in program effects across…

  15. Collaborative Imaginaries and Multi-Sited Ethnography: Space-Time Dimensions of Engagement in an Afterschool Science Programme for Girls

    ERIC Educational Resources Information Center

    Rahm, Jrene

    2012-01-01

    Temporal and spatial configurations that constitute learning and identity work across practices have been little explored in studies of science literacy development. Grounded in multi-sited ethnography, this paper explores diverse girls' engagement with and identity work in science locally, inside a newsletter activity in an afterschool programme…

  16. Distortions in Distributions of Impact Estimates in Multi-Site Trials: The Central Limit Theorem Is Not Your Friend

    ERIC Educational Resources Information Center

    May, Henry

    2014-01-01

    Interest in variation in program impacts--How big is it? What might explain it?--has inspired recent work on the analysis of data from multi-site experiments. One critical aspect of this problem involves the use of random or fixed effect estimates to visualize the distribution of impact estimates across a sample of sites. Unfortunately, unless the…

  17. Development and Implementation of a Multisite Evaluation for the Women, Co-Occurring Disorders and Violence Study

    ERIC Educational Resources Information Center

    Giard, Julienne; Hennigan, Karen; Huntington, Nicholas; Vogel, Wendy; Rinehart, Debbie; Mazelis, Ruta; Nadlicki, Terri; Veysey, Bonita M.

    2005-01-01

    In this article we describe the development and implementation of the Substance Abuse and Mental Health Services Administration's (SAMHSA's) multisite Women, Co-Occurring Disorders and Violence Study (WCDVS), highlighting some of the challenges encountered, decisions made, and lessons learned. Four themes are discussed. First, the unique…

  18. Year One Results from the Multisite Randomized Evaluation of the i3 Scale-Up of Reading Recovery

    ERIC Educational Resources Information Center

    May, Henry; Gray, Abigail; Sirinides, Philip; Goldsworthy, Heather; Armijo, Michael; Sam, Cecile; Gillespie, Jessica N.; Tognatta, Namrata

    2015-01-01

    Reading Recovery (RR) is a short-term, one-to-one intervention designed to help the lowest achieving readers in first grade. This article presents first-year results from the multisite randomized controlled trial (RCT) and implementation study under the $55 million Investing in Innovation (i3) Scale-Up Project. For the 2011-2012 school year, the…

  19. An Examination of Diversity within Three Southeastern Academic Libraries: A Mixed-Methods, Multi-Site Study

    ERIC Educational Resources Information Center

    Shaffer, Christopher A.

    2014-01-01

    The purpose of this study was to determine the extent to which three academic libraries in the Southeastern United States could be considered diverse. This was a multi-site, mixed methods study. It examined the climate and culture of the libraries, which was assessed through two methods; the first, through survey responses from full-time faculty…

  20. Awareness of Diagnosis and Knowledge of HPV in Women Patients: Data from a Multi-Site Study

    ERIC Educational Resources Information Center

    McCree, Donna Hubbard; Daley, Ellen M.; Gorbach, Pamina; Hamm, Robert M.; Sharpe, Patricia A.; Brandt, Heather M.; McFarlane, Mary; Kerndt, Peter; McDermott, Robert J.; Perrin, Karen M.; St. Lawrence, Janet S.

    2010-01-01

    Background: Persistent infection with high-risk types of human papillomavirus (HPV) is associated with cervical and other anogenital cancers. Purpose: This paper reports results of awareness of an HPV diagnosis and HPV knowledge from a multi-site study of HPV knowledge, attitudes and behavior, and the impact of an HPV diagnosis on women and their…

  1. Efficacy of a Process Improvement Intervention on Inmate Awareness of HIV Services: A Multi-Site Trial

    PubMed Central

    Hiller, Matthew L.; Albizu-García, Carmen E.; Pich, Michele; Patterson, Yvonne; O’Connell, Daniel J.

    2015-01-01

    The prevalence of HIV among U.S. inmates is much greater than in the general population, creating public health concerns and cost issues for the criminal justice system. The HIV Services and Treatment Implementation in Corrections protocol of the NIDA funded Criminal Justice Drug Abuse Treatment Studies cooperative tested the efficacy of an organizational process improvement strategy on improving HIV services in correctional facilities. For this paper, we analyzed efficacy of this strategy on improving inmate awareness and perceptions of HIV services. The study used a multi-site (n=28) clustered randomized trial approach. Facilities randomized to the experimental condition used a coach-driven local change team approach to improve HIV services at their facility. Facilities in the control condition were given a directive to improve HIV services on their own. Surveys about awareness and perceptions of HIV services were administered anonymously to inmates who were incarcerated in study facilities at baseline (n=1253) and follow-up (n=1048). A series of one-way ANOVAs were run to test whether there were differences between inmates in the experimental and control facilities at baseline and follow-up. Differences were observed at baseline, with the experimental group having significantly lower scores than the control group on key variables. But, at post-test, following the intervention, these differences were no longer significant. Taken in context of the findings from the main study, these results suggest that the change team approach to improving HIV services in correctional facilities is efficacious for improving inmates’ awareness and perceptions of HIV services. PMID:26203411

  2. Promotoras de Salud: roles, responsibilities, and contributions in a multisite community-based randomized controlled trial.

    PubMed

    Messias, DeAnne K Hilfinger; Parra-Medina, Deborah; Sharpe, Patricia A; Treviño, Laura; Koskan, Alexis M; Morales-Campos, Daisy

    2013-01-01

    There is widespread recognition of the cultural and linguistic appropriateness of (a Spanish term for community health workers [CHW]) in health education and outreach among Hispanic communities. Yet, there are significant gaps in the literature regarding the preparation, implementation, and evaluation of ' engagement in research. To address this gap, we examine ' research-related training, roles, responsibilities, and contributions in a community-based participatory research project involving a multisite randomized controlled trial (RCT) of a physical activity intervention for Mexican-origin women in Texas and South Carolina. We identify both benefits and challenges associated with ' engagement as community researchers; examine variations and differences in roles and responsibilities related to the research contexts, sites, settings, and individual characteristics; and discuss implications for research and practice. PMID:24695944

  3. MASCARA: The Multi-site All-Sky CAmeRA

    NASA Astrophysics Data System (ADS)

    Snellen, Inas; Stuik, Remko; Otten, Gilles; Bettonvil, Felix; Navarro, Ramon; Kenworthy, Matthew; de Mooij, Ernst; ter Horst, Rik; Le Poole, Rudolf; Lesage, Anna-Lea; Spronck, Julien

    2013-04-01

    The Multi-site All-Sky CAmeRA, MASCARA, is an instrument currently in the design phase, that is aimed to find the brightest transiting planet systems in the sky. It will consist of several stations across the globe, each monitoring the near-entire sky using a battery of CCD-detectors plus wide-field lenses, targeting stars in the V = 4 - 8 magnitude range. MASCARA will be able to detect individual transits from Jupiter-size planets over this whole magnitude range, while smaller planets will be found by co-adding transit events. We expect to discover up to a dozen bright transit systems in this way. These will be extremely valuable for atmospheric follow-up studies.

  4. Multi-site production planning in hybrid make-to-stock/make-to-order production environment

    NASA Astrophysics Data System (ADS)

    Rafiei, Hamed; Rabbani, Masoud; Kokabi, Reza

    2014-06-01

    Today competitive environment has enforced practitioners and researchers to pay great attention to issues enhancing both production and marketing competitiveness. To do so, it has been obligatory for the firms to consider production side activities while customer requirements are on the other side of competition. In this regard, hybrid make-to-stock (MTS)/make-to-order (MTO) production systems have revealed outstanding results. This paper addresses multi-site production planning of a hybrid manufacturing firm for the first time in the hybrid systems' body of literature. In this regard, a network of suppliers, manufacturers and customers is considered for which a mixed-integer mathematical model is proposed. Objective function of the proposed mathematical model seeks to maximize profitability of the manufacturing firm. Because of computational complexity of the developed mathematical model, a genetic algorithm is developed upon which numerical experiments are reported in order to show validity and applicability of the proposed model.

  5. Multisite silicon neural probes with integrated silicon nitride waveguides and gratings for optogenetic applications

    PubMed Central

    Shim, Euijae; Chen, Yu; Masmanidis, Sotiris; Li, Mo

    2016-01-01

    Optimal optogenetic perturbation of brain circuit activity often requires light delivery in a precise spatial pattern that cannot be achieved with conventional optical fibers. We demonstrate an implantable silicon-based probe with a compact light delivery system, consisting of silicon nitride waveguides and grating couplers for out-of-plane light emission with high spatial resolution. 473 nm light is coupled into and guided in cm-long waveguide and emitted at the output grating coupler. Using the direct cut-back and out-scattering measurement techniques, the propagation optical loss of the waveguide is measured to be below 3 dB/cm. The grating couplers provide collimated light emission with sufficient irradiance for neural stimulation. Finally, a probe with multisite light delivery with three output grating emitters from a single laser input is demonstrated. PMID:26941111

  6. Field fracturing multi-sites project. Annual report, August 1, 1995--July 31, 1996

    SciTech Connect

    1996-12-31

    The objective of the Field Fracturing Multi-Sites Project (M-Site) is to conduct experiments to definitively determine hydraulic fracture dimensions using remote well and treatment well diagnostic techniques. In addition, experiments are to be conducted to provide data that will resolve significant unknowns with regard to hydraulic fracture modeling, fracture fluid rheology and fracture treatment design. These experiments will be supported by a well-characterized subsurface environment, as well as surface facilities and equipment conducive to acquiring high-quality data. The primary Project goal is to develop a fully characterized, tight reservoir-typical, field-scale hydraulic fracturing test site to diagnose, characterize, and test hydraulic fracturing technology and performance. It is anticipated that the research work being conducted by the multi-disciplinary team of GRI and DOE contractors will lead to the development of a commercial fracture mapping tool/service.

  7. Brief strategic family therapy for adolescent drug abusers: a multi-site effectiveness study.

    PubMed

    Robbins, Michael S; Szapocznik, José; Horigian, Viviana E; Feaster, Daniel J; Puccinelli, Marc; Jacobs, Petra; Burlew, Kathy; Werstlein, Robert; Bachrach, Ken; Brigham, Greg

    2009-05-01

    Brief strategic family therapy (BSFT) is a manualized treatment designed to address aspects of family functioning associated with adolescent drug use and behavior problems (J. Szapocznik, U. Hervis, S. Schwartz, (2003). Brief strategic family therapy for adolescent drug abuse. (NIH Publication No. 03-4751). Bethesda, MD: National Institute on Drug Abuse). Within the National Institute on Drug Abuse's (NIDA's) Clinical Trials Network, BSFT is being compared to treatment as usual (TAU) in a multisite, prospective randomized clinical trial for drug using adolescents and their families in outpatient settings. The effectiveness of BSFT is being compared to TAU in reducing adolescent drug use, conduct problems, and sexually risky behaviors as well as in improving family functioning and adolescent prosocial behaviors. This paper describes the following aspects of the study: specific aims, research design and study organization, assessment of primary and secondary outcomes, study treatments, data analysis plan, and data monitoring and safety reporting.

  8. Childhood traumatic grief: a multi-site empirical examination of the construct and its correlates.

    PubMed

    Brown, Elissa J; Amaya-Jackson, Lisa; Cohen, Judith; Handel, Stephanie; Thiel De Bocanegra, Heike; Zatta, Eileen; Goodman, Robin F; Mannarino, Anthony

    2008-01-01

    This study evaluated the construct of childhood traumatic grief (CTG) and its correlates through a multi-site assessment of 132 bereaved children and adolescents. Youth completed a new measure of the characteristics, attributions, and reactions to exposure to death (CARED), as well as measures of CTG, posttraumatic stress disorder (PTSD), depression, and anger. CTG was distinct from but highly correlated with PTSD, depression, and, to a lesser degree, anger. In contrast to a recent study of complicated grief, CTG severity was significantly associated with the degree to which the death was viewed as traumatic. CTG was also associated with caregivers' emotional reaction at the time of the death and caregivers' current sadness. Clinical implications and recommendations for future research are discussed.

  9. Existence of multisite intrinsic localized modes in one-dimensional Debye crystals

    SciTech Connect

    Koukouloyannis, V.; Kourakis, I.

    2007-07-15

    The existence of highly localized multisite oscillatory structures (discrete multibreathers) in a nonlinear Klein-Gordon chain which is characterized by an inverse dispersion law is proven and their linear stability is investigated. The results are applied in the description of vertical (transverse, off-plane) dust grain motion in dusty plasma crystals, by taking into account the lattice discreteness and the sheath electric and/or magnetic field nonlinearity. Explicit values from experimental plasma discharge experiments are considered. The possibility for the occurrence of multibreathers associated with vertical charged dust grain motion in strongly coupled dusty plasmas (dust crystals) is thus established. From a fundamental point of view, this study aims at providing a rigorous investigation of the existence of intrinsic localized modes in Debye crystals and/or dusty plasma crystals and, in fact, suggesting those lattices as model systems for the study of fundamental crystal properties.

  10. A frailty-contagion model for multi-site hourly precipitation driven by atmospheric covariates

    NASA Astrophysics Data System (ADS)

    Koch, Erwan; Naveau, Philippe

    2015-04-01

    Accurate stochastic simulations of hourly precipitation are needed for impact studies at local spatial scales. Statistically, hourly precipitation data represent a difficult challenge. They are non-negative, skewed, heavy tailed, contain a lot of zeros (dry hours) and they have complex temporal structures (e.g., long persistence of dry episodes). Inspired by frailty-contagion approaches used in finance and insurance, we propose a multi-site precipitation simulator that, given appropriate regional atmospheric variables, can simultaneously handle dry events and heavy rainfall periods. One advantage of our model is its conceptual simplicity in its dynamical structure. In particular, the temporal variability is represented by a common factor based on a few classical atmospheric covariates like temperatures, pressures and others. Our inference approach is tested on simulated data and applied on measurements made in the northern part of French Brittany.

  11. Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

    PubMed Central

    Gault, Joseph; Ferber, Mathias; Machata, Silke; Imhaus, Anne-Flore; Malosse, Christian; Charles-Orszag, Arthur; Millien, Corinne; Bouvier, Guillaume; Bardiaux, Benjamin; Péhau-Arnaudet, Gérard; Klinge, Kelly; Podglajen, Isabelle; Ploy, Marie Cécile; Seifert, H. Steven; Nilges, Michael; Chamot-Rooke, Julia; Duménil, Guillaume

    2015-01-01

    The ability of pathogens to cause disease depends on their aptitude to escape the immune system. Type IV pili are extracellular filamentous virulence factors composed of pilin monomers and frequently expressed by bacterial pathogens. As such they are major targets for the host immune system. In the human pathogen Neisseria meningitidis, strains expressing class I pilins contain a genetic recombination system that promotes variation of the pilin sequence and is thought to aid immune escape. However, numerous hypervirulent clinical isolates express class II pilins that lack this property. This raises the question of how they evade immunity targeting type IV pili. As glycosylation is a possible source of antigenic variation it was investigated using top-down mass spectrometry to provide the highest molecular precision on the modified proteins. Unlike class I pilins that carry a single glycan, we found that class II pilins display up to 5 glycosylation sites per monomer on the pilus surface. Swapping of pilin class and genetic background shows that the pilin primary structure determines multisite glycosylation while the genetic background determines the nature of the glycans. Absence of glycosylation in class II pilins affects pilus biogenesis or enhances pilus-dependent aggregation in a strain specific fashion highlighting the extensive functional impact of multisite glycosylation. Finally, molecular modeling shows that glycans cover the surface of class II pilins and strongly decrease antibody access to the polypeptide chain. This strongly supports a model where strains expressing class II pilins evade the immune system by changing their sugar structure rather than pilin primary structure. Overall these results show that sequence invariable class II pilins are cloaked in glycans with extensive functional and immunological consequences. PMID:26367394

  12. The brain-derived neurotrophic factor pathway, life stress, and chronic multi-site musculoskeletal pain

    PubMed Central

    Milaneschi, Yuri; Jansen, Rick; Elzinga, Bernet M; Dekker, Joost; Penninx, Brenda WJH

    2016-01-01

    Introduction Brain-derived neurotrophic factor (BDNF) disturbances and life stress, both independently and in interaction, have been hypothesized to induce chronic pain. We examined whether (a) the BDNF pathway (val66met genotype, gene expression, and serum levels), (b) early and recent life stress, and (c) their interaction are associated with the presence and severity of chronic multi-site musculoskeletal pain. Methods Cross-sectional data are from 1646 subjects of the Netherlands Study of Depression and Anxiety. The presence and severity of chronic multi-site musculoskeletal pain were determined using the Chronic Pain Grade (CPG) questionnaire. The BDNF val66met polymorphism, BDNF gene expression, and BDNF serum levels were measured. Early life stress before the age of 16 was assessed by calculating a childhood trauma index using the Childhood Trauma Interview. Recent life stress was assessed as the number of recent adverse life events using the List of Threatening Events Questionnaire. Results Compared to val66val, BDNF met carriers more often had chronic pain, whereas no differences were found for BDNF gene expression and serum levels. Higher levels of early and recent stress were both associated with the presence and severity of chronic pain (p < 0.001). No interaction effect was found for the BDNF pathway with life stress in the associations with chronic pain presence and severity. Conclusions This study suggests that the BDNF gene marks vulnerability for chronic pain. Although life stress did not alter the impact of BDNF on chronic pain, it seems an independent factor in the onset and persistence of chronic pain. PMID:27145806

  13. Model-data fusion across ecosystems: from multi-site optimizations to global simulations

    NASA Astrophysics Data System (ADS)

    Kuppel, S.; Peylin, P.; Maignan, F.; Chevallier, F.; Kiely, G.; Montagnani, L.; Cescatti, A.

    2014-05-01

    This study uses a variational data assimilation framework to simultaneously constrain a global ecosystem model with eddy covariance measurements of daily net carbon (NEE) and latent heat (LE) fluxes from a large number of sites grouped in seven plant functional types (PFTs). It is an attempt to bridge the gap between the numerous site-specific parameter optimization works found in the literature and the generic parameterization used by most land surface models within each PFT. The present multi-site approach allows deriving PFT-generic sets of optimized parameters enhancing the agreement between measured and simulated fluxes at most of the sites considered, with performances often comparable to those of the corresponding site-specific optimizations. Besides reducing the PFT-averaged model-data root-mean-square difference (RMSD) and the associated daily output uncertainty, the optimization improves the simulated CO2 balance at tropical and temperate forests sites. The major site-level NEE adjustments at the seasonal scale are: reduced amplitude in C3 grasslands and boreal forests, increased seasonality in temperate evergreen forests, and better model-data phasing in temperate deciduous broadleaf forests. Conversely, the poorer performances in tropical evergreen broadleaf forests points to deficiencies regarding the modeling of phenology and soil water stress for this PFT. An evaluation with data-oriented estimates of photosynthesis (GPP) and ecosystem respiration (Reco) rates indicates distinctively improved simulations of both gross fluxes. The multi-site parameter sets are then tested against CO2 concentrations measured at 53 locations around the globe, showing significant adjustments of the modeled seasonality of atmospheric CO2 concentration, whose relevance seems PFT-dependent, along with an improved interannual variability. Lastly, a global scale evaluation with remote sensing NDVI measurements indicates an improvement of the simulated seasonal variations of

  14. Model-data fusion across ecosystems: from multisite optimizations to global simulations

    NASA Astrophysics Data System (ADS)

    Kuppel, S.; Peylin, P.; Maignan, F.; Chevallier, F.; Kiely, G.; Montagnani, L.; Cescatti, A.

    2014-11-01

    This study uses a variational data assimilation framework to simultaneously constrain a global ecosystem model with eddy covariance measurements of daily net ecosystem exchange (NEE) and latent heat (LE) fluxes from a large number of sites grouped in seven plant functional types (PFTs). It is an attempt to bridge the gap between the numerous site-specific parameter optimization works found in the literature and the generic parameterization used by most land surface models within each PFT. The present multisite approach allows deriving PFT-generic sets of optimized parameters enhancing the agreement between measured and simulated fluxes at most of the sites considered, with performances often comparable to those of the corresponding site-specific optimizations. Besides reducing the PFT-averaged model-data root-mean-square difference (RMSD) and the associated daily output uncertainty, the optimization improves the simulated CO2 balance at tropical and temperate forests sites. The major site-level NEE adjustments at the seasonal scale are reduced amplitude in C3 grasslands and boreal forests, increased seasonality in temperate evergreen forests, and better model-data phasing in temperate deciduous broadleaf forests. Conversely, the poorer performances in tropical evergreen broadleaf forests points to deficiencies regarding the modelling of phenology and soil water stress for this PFT. An evaluation with data-oriented estimates of photosynthesis (GPP - gross primary productivity) and ecosystem respiration (Reco) rates indicates distinctively improved simulations of both gross fluxes. The multisite parameter sets are then tested against CO2 concentrations measured at 53 locations around the globe, showing significant adjustments of the modelled seasonality of atmospheric CO2 concentration, whose relevance seems PFT-dependent, along with an improved interannual variability. Lastly, a global-scale evaluation with remote sensing NDVI (normalized difference vegetation index

  15. Spectroscopic Survey of Circumstellar Disks in Orion

    NASA Astrophysics Data System (ADS)

    Contreras, Maria; Hernandez, Jesus; Olguin, Lorenzo; Briceno, Cesar

    2013-07-01

    As a second stage of a project focused on characterizing candidate stars bearing a circumstellar disk in Orion, we present a spectroscopic follow-up of a set of about 170 bright stars. The present set of stars was selected by their optical (UBVRI) and infrared behavior in different color-color and color-magnitude diagrams. Observations were carried out at the Observatorio Astronomico Nacional located at the Sierra San Pedro Martir in B.C., Mexico and at the Observatorio Guillermo Haro in Cananea, Sonora, Mexico. Low-resolution spectra were obtained for all candidates in the sample. Using the SPTCLASS code, we have obtained spectral types and equivalent widths of the Li I 6707 and Halpha lines for each one of the stars. This project is a cornerstone of a large scale survey aimed to obtain stellar parameters in a homogeneous way using spectroscopic data. This work was partially supported by UNAM-PAPIIT grant IN-109311.

  16. THE zCOSMOS 10k-BRIGHT SPECTROSCOPIC SAMPLE

    SciTech Connect

    Lilly, Simon J.; Maier, Christian; Carollo, Marcella; Caputi, Karina; Le Brun, Vincent; Kneib, Jean-Paul; Le Fevre, Olivier; De la Torre, Sylvain; De Ravel, Loic; Mainieri, Vincenzo; Mignoli, Marco; Zamorani, Gianni; Bardelli, Sandro; Bolzonella, Micol; Coppa, Graziano; Scodeggio, Marco; Contini, Thierry; Bongiorno, Angela; Cucciati, Olga

    2009-10-01

    We present spectroscopic redshifts of a large sample of galaxies with I {sub AB} < 22.5 in the COSMOS field, measured from spectra of 10,644 objects that have been obtained in the first two years of observations in the zCOSMOS-bright redshift survey. These include a statistically complete subset of 10,109 objects. The average accuracy of individual redshifts is 110 km s{sup -1}, independent of redshift. The reliability of individual redshifts is described by a Confidence Class that has been empirically calibrated through repeat spectroscopic observations of over 600 galaxies. There is very good agreement between spectroscopic and photometric redshifts for the most secure Confidence Classes. For the less secure Confidence Classes, there is a good correspondence between the fraction of objects with a consistent photometric redshift and the spectroscopic repeatability, suggesting that the photometric redshifts can be used to indicate which of the less secure spectroscopic redshifts are likely right and which are probably wrong, and to give an indication of the nature of objects for which we failed to determine a redshift. Using this approach, we can construct a spectroscopic sample that is 99% reliable and which is 88% complete in the sample as a whole, and 95% complete in the redshift range 0.5 < z < 0.8. The luminosity and mass completeness levels of the zCOSMOS-bright sample of galaxies is also discussed.

  17. Spectroscopic Detection of Pathogens

    SciTech Connect

    ALAM,M. KATHLEEN; TIMLIN,JERILYN A.; MARTIN,LAURA E.; HJELLE,DRIAN; LYONS,RICK; GARRISON,KRISTIN

    2000-11-01

    The goal of this LDRD Research project was to provide a preliminary examination of the use of infrared spectroscopy as a tool to detect the changes in cell cultures upon activation by an infectious agent. Due to a late arrival of funding, only 5 months were available to transfer and setup equipment at UTTM,develop cell culture lines, test methods of in-situ activation and collect kinetic data from activated cells. Using attenuated total reflectance (ATR) as a sampling method, live cell cultures were examined prior to and after activation. Spectroscopic data were collected from cells immediately after activation in situ and, in many cases for five successive hours. Additional data were collected from cells activated within a test tube (pre-activated), in both transmission mode as well as in ATR mode. Changes in the infrared data were apparent in the transmission data collected from the pre-activated cells as well in some of the pre-activated ATR data. Changes in the in-situ activated spectral data were only occasionally present due to (1) the limited time cells were studied and (2) incomplete activation. Comparison of preliminary data to infrared bands reported in the literature suggests the primary changes seen are due an increase in ribonucleic acid (RNA) production. This work will be continued as part of a 3 year DARPA grant.

  18. Spectroscopic classification of supernova candidates

    NASA Astrophysics Data System (ADS)

    Hodgkin, S. T.; Hall, A.; Fraser, M.; Campbell, H.; Wyrzykowski, L.; Kostrzewa-Rutkowska, Z.; Pietro, N.

    2014-09-01

    We report the spectroscopic classification of four supernovae at the 2.5m Isaac Newton Telescope on La Palma, using the Intermediate Dispersion Spectrograph and the R300V grating (3500-8000 Ang; ~6 Ang resolution).

  19. Spectroscopic Classification of PS16chs with SOAR/Goodman

    NASA Astrophysics Data System (ADS)

    Miller, J. A.; Hounsell, R. A.; Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-05-01

    We report the classification of PS16chs from spectroscopic observation with the Goodman spectrograph on the SOAR telescope. The observation was made on 2016 May 08 UT. We classify PS16chs as a SN Ia near maximum light at z = 0.19.

  20. A general Bayesian framework for calibrating and evaluating stochastic models of annual multi-site hydrological data

    NASA Astrophysics Data System (ADS)

    Frost, Andrew J.; Thyer, Mark A.; Srikanthan, R.; Kuczera, George

    2007-07-01

    SummaryMulti-site simulation of hydrological data are required for drought risk assessment of large multi-reservoir water supply systems. In this paper, a general Bayesian framework is presented for the calibration and evaluation of multi-site hydrological data at annual timescales. Models included within this framework are the hidden Markov model (HMM) and the widely used lag-1 autoregressive (AR(1)) model. These models are extended by the inclusion of a Box-Cox transformation and a spatial correlation function in a multi-site setting. Parameter uncertainty is evaluated using Markov chain Monte Carlo techniques. Models are evaluated by their ability to reproduce a range of important extreme statistics and compared using Bayesian model selection techniques which evaluate model probabilities. The case study, using multi-site annual rainfall data situated within catchments which contribute to Sydney's main water supply, provided the following results: Firstly, in terms of model probabilities and diagnostics, the inclusion of the Box-Cox transformation was preferred. Secondly the AR(1) and HMM performed similarly, while some other proposed AR(1)/HMM models with regionally pooled parameters had greater posterior probability than these two models. The practical significance of parameter and model uncertainty was illustrated using a case study involving drought security analysis for urban water supply. It was shown that ignoring parameter uncertainty resulted in a significant overestimate of reservoir yield and an underestimation of system vulnerability to severe drought.

  1. Quasi-static and multi-site high velocity impact response of composite structures

    NASA Astrophysics Data System (ADS)

    Deka, Lakshya

    Understanding of low and high velocity transverse impact of laminated fiber reinforced composites is of interest in military, aerospace, marine and civilian structures. Recent advances in the field of numerical simulation provide a means of predicting the performance characteristics of layered materials for impact protection. The overall objective of this work is to investigate the behavior of laminated composites which include both thermoplastic and thermoset systems subjected to quasi-static, low and high velocity impact; both from an experimental and numerical modeling view point. To analyze this problem, a series of quasi-static, low and high velocity impact tests have been performed on laminated composite plates namely E-glass/polypropylene, S2-glass/epoxy and carbon/polyphenylene sulphide. To analyze the perforation mechanism, ballistic limit and damage evolution, an explicit three-dimensional finite element code LS-DYNA is used. Selecting proper material models and contact definition is one of the major criteria for obtaining accurate numerical simulation. Material model 162 (MAT 162), a progressive failure model based on modified Hashin's criteria and continuum damage mechanics (CDM) has been assigned to predict failure of the laminate. This approach is used because during transverse impact, a composite laminate undergoes progressive damage. The laminate and the projectile are meshed using brick elements with single integration points. The impact velocity ranges from 180 to 400 m s -1. This work focuses on three main aspects; (i) To obtain static and dynamic material properties to incorporate into the finite element model and predict the ballistic limit of a composite laminate based on the information from quasi-static punch shear test; (ii) To understand penetration, material erosion, ballistic limit and delamination mechanisms for single and multi-site high velocity (or ballistic) impact of composite laminates; (iii) To investigate the different failure

  2. Problematising Short-Term Participant Observation and Multi-Method Ethnographic Studies

    ERIC Educational Resources Information Center

    Brockmann, Michaela

    2011-01-01

    This article reports on a study of apprentices in England and Germany designed to explore young people's learner identities over time and in relation to particular learning environments. The research adopts a multi-method ethnographic approach, combining biographical interviews with multi-site participant observation. The article problematises the…

  3. Preliminary results on the fracture analysis of multi-site cracking of lap joints in aircraft skins

    NASA Astrophysics Data System (ADS)

    Beuth, J. L., Jr.; Hutchinson, John W.

    1992-07-01

    Results of a fracture mechanics analysis relevant to fatigue crack growth at rivets in lap joints of aircraft skins are presented. Multi-site damage (MSD) is receiving increased attention within the context of problems of aging aircraft. Fracture analyses previously carried out include small-scale modeling of rivet/skin interactions, larger-scale two-dimensional models of lap joints similar to that developed here, and full scale three-dimensional models of large portions of the aircraft fuselage. Fatigue testing efforts have included flat coupon specimens, two-dimensional lap joint tests, and full scale tests on specimens designed to closely duplicate aircraft sections. Most of this work is documented in the proceedings of previous symposia on the aging aircraft problem. The effect MSD has on the ability of skin stiffeners to arrest the growth of long skin cracks is a particularly important topic that remains to be addressed. One of the most striking features of MSD observed in joints of some test sections and in the joints of some of the older aircraft fuselages is the relative uniformity of the fatigue cracks from rivet to rivet along an extended row of rivets. This regularity suggests that nucleation of the cracks must not be overly difficult. Moreover, it indicates that there is some mechanism which keeps longer cracks from running away from shorter ones, or, equivalently, a mechanism for shorter cracks to catch-up with longer cracks. This basic mechanism has not been identified, and one of the objectives of the work is to see to what extent the mechanism is revealed by a fracture analysis of the MSD cracks. Another related aim is to present accurate stress intensity factor variations with crack length which can be used to estimate fatigue crack growth lifetimes once cracks have been initiated. Results are presented which illustrate the influence of load shedding from rivets with long cracks to neighboring rivets with shorter cracks. Results are also included

  4. Preliminary results on the fracture analysis of multi-site cracking of lap joints in aircraft skins

    NASA Technical Reports Server (NTRS)

    Beuth, J. L., Jr.; Hutchinson, John W.

    1992-01-01

    Results of a fracture mechanics analysis relevant to fatigue crack growth at rivets in lap joints of aircraft skins are presented. Multi-site damage (MSD) is receiving increased attention within the context of problems of aging aircraft. Fracture analyses previously carried out include small-scale modeling of rivet/skin interactions, larger-scale two-dimensional models of lap joints similar to that developed here, and full scale three-dimensional models of large portions of the aircraft fuselage. Fatigue testing efforts have included flat coupon specimens, two-dimensional lap joint tests, and full scale tests on specimens designed to closely duplicate aircraft sections. Most of this work is documented in the proceedings of previous symposia on the aging aircraft problem. The effect MSD has on the ability of skin stiffeners to arrest the growth of long skin cracks is a particularly important topic that remains to be addressed. One of the most striking features of MSD observed in joints of some test sections and in the joints of some of the older aircraft fuselages is the relative uniformity of the fatigue cracks from rivet to rivet along an extended row of rivets. This regularity suggests that nucleation of the cracks must not be overly difficult. Moreover, it indicates that there is some mechanism which keeps longer cracks from running away from shorter ones, or, equivalently, a mechanism for shorter cracks to catch-up with longer cracks. This basic mechanism has not been identified, and one of the objectives of the work is to see to what extent the mechanism is revealed by a fracture analysis of the MSD cracks. Another related aim is to present accurate stress intensity factor variations with crack length which can be used to estimate fatigue crack growth lifetimes once cracks have been initiated. Results are presented which illustrate the influence of load shedding from rivets with long cracks to neighboring rivets with shorter cracks. Results are also included

  5. The Gaia-ESO Public Spectroscopic Survey

    NASA Astrophysics Data System (ADS)

    Gilmore, G.; Randich, S.; Asplund, M.; Binney, J.; Bonifacio, P.; Drew, J.; Feltzing, S.; Ferguson, A.; Jeffries, R.; Micela, G.; Negueruela, I.; Prusti, T.; Rix, H.-W.; Vallenari, A.; Alfaro, E.; Allende-Prieto, C.; Babusiaux, C.; Bensby, T.; Blomme, R.; Bragaglia, A.; Flaccomio, E.; François, P.; Irwin, M.; Koposov, S.; Korn, A.; Lanzafame, A.; Pancino, E.; Paunzen, E.; Recio-Blanco, A.; Sacco, G.; Smiljanic, R.; Van Eck, S.; Walton, N.; Aden, D.; Aerts, C.; Affer, L.; Alcala, J.-M.; Altavilla, G.; Alves, J.; Antoja, T.; Arenou, F.; Argiroffi, C.; Asensio Ramos, A.; Bailer-Jones, C.; Balaguer-Nunez, L.; Bayo, A.; Barbuy, B.; Barisevicius, G.; Barrado y Navascues, D.; Battistini, C.; Bellas Velidis, I.; Bellazzini, M.; Belokurov, V.; Bergemann, M.; Bertelli, G.; Biazzo, K.; Bienayme, O.; Bland-Hawthorn, J.; Boeche, C.; Bonito, S.; Boudreault, S.; Bouvier, J.; Brandao, I.; Brown, A.; de Bruijne, J.; Burleigh, M.; Caballero, J.; Caffau, E.; Calura, F.; Capuzzo-Dolcetta, R.; Caramazza, M.; Carraro, G.; Casagrande, L.; Casewell, S.; Chapman, S.; Chiappini, C.; Chorniy, Y.; Christlieb, N.; Cignoni, M.; Cocozza, G.; Colless, M.; Collet, R.; Collins, M.; Correnti, M.; Covino, E.; Crnojevic, D.; Cropper, M.; Cunha, M.; Damiani, F.; David, M.; Delgado, A.; Duffau, S.; Edvardsson, B.; Eldridge, J.; Enke, H.; Eriksson, K.; Evans, N. W.; Eyer, L.; Famaey, B.; Fellhauer, M.; Ferreras, I.; Figueras, F.; Fiorentino, G.; Flynn, C.; Folha, D.; Franciosini, E.; Frasca, A.; Freeman, K.; Fremat, Y.; Friel, E.; Gaensicke, B.; Gameiro, J.; Garzon, F.; Geier, S.; Geisler, D.; Gerhard, O.; Gibson, B.; Gomboc, A.; Gomez, A.; Gonzalez-Fernandez, C.; Gonzalez Hernandez, J.; Gosset, E.; Grebel, E.; Greimel, R.; Groenewegen, M.; Grundahl, F.; Guarcello, M.; Gustafsson, B.; Hadrava, P.; Hatzidimitriou, D.; Hambly, N.; Hammersley, P.; Hansen, C.; Haywood, M.; Heber, U.; Heiter, U.; Held, E.; Helmi, A.; Hensler, G.; Herrero, A.; Hill, V.; Hodgkin, S.; Huelamo, N.; Huxor, A.; Ibata, R.; Jackson, R.; de Jong, R.; Jonker, P.; Jordan, S.; Jordi, C.; Jorissen, A.; Katz, D.; Kawata, D.; Keller, S.; Kharchenko, N.; Klement, R.; Klutsch, A.; Knude, J.; Koch, A.; Kochukhov, O.; Kontizas, M.; Koubsky, P.; Lallement, R.; de Laverny, P.; van Leeuwen, F.; Lemasle, B.; Lewis, G.; Lind, K.; Lindstrom, H. P. E.; Lobel, A.; Lopez Santiago, J.; Lucas, P.; Ludwig, H.; Lueftinger, T.; Magrini, L.; Maiz Apellaniz, J.; Maldonado, J.; Marconi, G.; Marino, A.; Martayan, C.; Martinez-Valpuesta, I.; Matijevic, G.; McMahon, R.; Messina, S.; Meyer, M.; Miglio, A.; Mikolaitis, S.; Minchev, I.; Minniti, D.; Moitinho, A.; Momany, Y.; Monaco, L.; Montalto, M.; Monteiro, M. J.; Monier, R.; Montes, D.; Mora, A.; Moraux, E.; Morel, T.; Mowlavi, N.; Mucciarelli, A.; Munari, U.; Napiwotzki, R.; Nardetto, N.; Naylor, T.; Naze, Y.; Nelemans, G.; Okamoto, S.; Ortolani, S.; Pace, G.; Palla, F.; Palous, J.; Parker, R.; Penarrubia, J.; Pillitteri, I.; Piotto, G.; Posbic, H.; Prisinzano, L.; Puzeras, E.; Quirrenbach, A.; Ragaini, S.; Read, J.; Read, M.; Reyle, C.; De Ridder, J.; Robichon, N.; Robin, A.; Roeser, S.; Romano, D.; Royer, F.; Ruchti, G.; Ruzicka, A.; Ryan, S.; Ryde, N.; Santos, N.; Sanz Forcada, J.; Sarro Baro, L. M.; Sbordone, L.; Schilbach, E.; Schmeja, S.; Schnurr, O.; Schoenrich, R.; Scholz, R.-D.; Seabroke, G.; Sharma, S.; De Silva, G.; Smith, M.; Solano, E.; Sordo, R.; Soubiran, C.; Sousa, S.; Spagna, A.; Steffen, M.; Steinmetz, M.; Stelzer, B.; Stempels, E.; Tabernero, H.; Tautvaisiene, G.; Thevenin, F.; Torra, J.; Tosi, M.; Tolstoy, E.; Turon, C.; Walker, M.; Wambsganss, J.; Worley, C.; Venn, K.; Vink, J.; Wyse, R.; Zaggia, S.; Zeilinger, W.; Zoccali, M.; Zorec, J.; Zucker, D.; Zwitter, T.; Gaia-ESO Survey Team

    2012-03-01

    The Gaia-ESO Public Spectroscopic Survey has begun and will obtain high quality spectroscopy of some 100000 Milky Way stars, in the field and in open clusters, down to magnitude 19, systematically covering all the major components of the Milky Way. This survey will provide the first homogeneous overview of the distributions of kinematics and chemical element abundances in the Galaxy. The motivation, organisation and implementation of the Gaia-ESO Survey are described, emphasising the complementarity with the ESA Gaia mission. Spectra from the very first observing run of the survey are presented.

  6. Facilitating outpatient treatment entry following detoxification for injection drug use: a multisite test of three interventions.

    PubMed

    Campbell, Barbara K; Fuller, Bret E; Lee, Eun Sul; Tillotson, Carrie; Woelfel, Tiffany; Jenkins, Lindsay; Robinson, James; Booth, Robert E; McCarty, Dennis

    2009-06-01

    A multisite, randomized trial within the National Drug Abuse Treatment Clinical Trials Network (CTN) was conducted to test 3 interventions to enhance treatment initiation following detoxification: (a) a single session, therapeutic alliance intervention (TA) added to usual treatment; (b) a 2-session, counseling and education, HIV/HCV risk reduction intervention (C&E), added to usual treatment; and (c) treatment as usual (TAU) only. Injection drug users (n=632) enrolled in residential detoxification at 8 community treatment programs were randomized to 1 of the 3 study conditions. TA participants reported entering outpatient treatment sooner and in greater numbers than TAU participants. Reported treatment entry for C&E fell between TA and TAU with no significant differences between C&E and the other conditions. There were no differences among the interventions in retention, as measured by weeks of outpatient treatment for all participants who reported treatment entry. Alliance building interventions appear to be effective in facilitating transfer from detoxification to outpatient treatment, but additional treatment engagement interventions may be necessary to improve retention. PMID:19586142

  7. Fracture analysis of multi-site cracking in fuselage lap joints

    NASA Astrophysics Data System (ADS)

    Beuth, J. L.; Hutchinson, J. W.

    1994-09-01

    A two-dimensional plane stress elastic fracture mechanics analysis of a cracked lap joint fastened by rigid pins is presented and results are applied to the problem of multi-site damage (MSD) in riveted lap joints of aircraft fuselage skins. Two problems are addressed, the problem of equal length MSD cracks and the problem of alternating length MSD cracks. For the problem of equal length cracks, two models of rivet/skin interactions are studied and the role of residual stresses due to the riveting process is explored. Stress intensity factors are obtained as a function of normalized crack length. Also, the load distribution among rivet rows and the compliance change of the joint due to MSD cracking are obtained. For the problem of alternating length cracks, attention is focussed on how load is distributed between columns of rivets and how this load shedding can alter crack tip stress intensity factors. The equal and alternating length crack analyses reveal no clear-cut mechanism to explain the relative uniformity of fatigue cracks emerging from lap joint rivet holes in actual aircraft and in mechanical lap joint tests.

  8. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users

    PubMed Central

    Carroll, Kathleen M.; Martino, Steve; Ball, Samuel A.; Nich, Charla; Frankforter, Tami; Anez, Luis M; Paris, Manuel; Suarez-Morales, Lourdes; Szapocznik, José; Miller, William R.; Rosa, Carmen; Matthews, Julie; Farentinos, Chris

    2009-01-01

    Hispanic individuals are underrepresented in clinical and research populations and often excluded from clinical trials in the US. Hence, there are few data on the effectiveness of most empirically validated therapies for Hispanic substance users. We conducted a multisite randomized trial comparing the effectiveness of three individual sessions of motivational enhancement therapy (MET) to three individual sessions of counseling as usual (CAU) on treatment retention and frequency of substance use, with all assessment and treatment sessions conducted in Spanish among 405 individuals seeking treatment for any type of current substance use. Treatment exposure was good, with 66% of participants completing all three protocol sessions. Although both interventions resulted in reductions in substance use during the 4-week therapy phase, there were no significant treatment condition by time interactions nor site by treatment condition interactions. Results suggest that the individual treatments delivered in Spanish were both attractive to and effective with this heterogeneous group of Hispanic adults, but the differential effectiveness of MET may be limited to those whose primary substance use problem is alcohol and may be fairly modest in magnitude. PMID:19803579

  9. Multisite Infection with Mycobacterium abscessus after Replacement of Breast Implants and Gluteal Lipofilling.

    PubMed

    Rüegg, Eva; Cheretakis, Alexandre; Modarressi, Ali; Harbarth, Stephan; Pittet-Cuénod, Brigitte

    2015-01-01

    Introduction. Medical tourism for aesthetic surgery is popular. Nontuberculous mycobacteria (NTM) occasionally cause surgical-site infections. As NTM grow in biofilms, implantations of foreign bodies are at risk. Due to late manifestation, infections occur when patients are back home, where they must be managed properly. Case Report. A 39-year-old healthy female was referred for acute infection of the right gluteal area. Five months before, she had breast implants replacement, abdominal liposuction, and gluteal lipofilling in Mexico. Three months postoperatively, implants were removed for NTM-infection in Switzerland. Adequate antibiotic treatment was stopped after seven days for drug-related hepatitis. At entrance, gluteal puncture for bacterial analysis was performed. MRI showed large subcutaneous collection. Debridement under general anaesthesia was followed by open wound management. Total antibiotic treatment was 20 weeks. Methods. Bacterial analysis of periprosthetic and gluteal liquids included Gram-stain plus acid-fast stain, and aerobic, anaerobic and mycobacterial cultures.  Results. In periprosthetic fluid, Mycobacterium abscessus, Propionibacterium, and Staphylococcus epidermidis were identified. The same M. abscessus strain was found gluteally. The gluteal wound healed within six weeks. At ten months' follow-up, gluteal asymmetry persists for deep scarring. Conclusion. This case presents major complications of multisite aesthetic surgery. Surgical-site infections in context of medical tourism need appropriate bacteriological investigations, considering potential NTM-infections.

  10. Multisite Infection with Mycobacterium abscessus after Replacement of Breast Implants and Gluteal Lipofilling

    PubMed Central

    Rüegg, Eva; Cheretakis, Alexandre; Modarressi, Ali; Harbarth, Stephan; Pittet-Cuénod, Brigitte

    2015-01-01

    Introduction. Medical tourism for aesthetic surgery is popular. Nontuberculous mycobacteria (NTM) occasionally cause surgical-site infections. As NTM grow in biofilms, implantations of foreign bodies are at risk. Due to late manifestation, infections occur when patients are back home, where they must be managed properly. Case Report. A 39-year-old healthy female was referred for acute infection of the right gluteal area. Five months before, she had breast implants replacement, abdominal liposuction, and gluteal lipofilling in Mexico. Three months postoperatively, implants were removed for NTM-infection in Switzerland. Adequate antibiotic treatment was stopped after seven days for drug-related hepatitis. At entrance, gluteal puncture for bacterial analysis was performed. MRI showed large subcutaneous collection. Debridement under general anaesthesia was followed by open wound management. Total antibiotic treatment was 20 weeks. Methods. Bacterial analysis of periprosthetic and gluteal liquids included Gram-stain plus acid-fast stain, and aerobic, anaerobic and mycobacterial cultures.  Results. In periprosthetic fluid, Mycobacterium abscessus, Propionibacterium, and Staphylococcus epidermidis were identified. The same M. abscessus strain was found gluteally. The gluteal wound healed within six weeks. At ten months' follow-up, gluteal asymmetry persists for deep scarring. Conclusion. This case presents major complications of multisite aesthetic surgery. Surgical-site infections in context of medical tourism need appropriate bacteriological investigations, considering potential NTM-infections. PMID:25893122

  11. Outcome of ECT by Race in the CORE Multi-Site Study

    PubMed Central

    Williams, Mark; Rummans, Teresa; Sampson, Shirlene; Knapp, Rebecca; Mueller, Martina; Husain, Mustafa M.; Fink, Max; Rasmussen, Keith; O’Connor, Kevin; Smith, Glenn; Petrides, George; Kellner, Charles H.

    2014-01-01

    Objective The authors examine the differences in outcome between black and white patients receiving ECT as a part of the CORE multi-site study. Methods A total of 624 patients were enrolled in an NIMH-funded, randomized controlled ECT trial comparing the efficacy of continuation ECT versus continuation pharmacotherapy between 1997 and 2004. This analysis focuses on the 32 black and 483 white patients who participated in phase I of the study. The authors compared baseline demographic and clinical variables, and acute outcomes of these two groups. Results Compared to whites, far fewer blacks participated in the study. Those who did were less likely to have failed adequate medication trials and were more likely to have psychotic features. Their initial HAMD24 scores were higher than whites, and they showed a greater reduction in these HAMD24 scores by the end of the treatment period. While sample size limited the statistical significance of the findings, black patients also showed a higher rate of remission after an acute phase of ECT. Conclusions This study found that black and white patients with major depressive disorder had comparable outcomes. We also found that fewer black patients received ECT than whites, a difference that has been reported in other samples. PMID:18580553

  12. Multisite Promiscuity in the Processing of Endogenous Substrates By Human Carboxylesterase 1

    SciTech Connect

    Bencharit, S.; Edwards, C.C.; Morton, C.L.; Howard-Williams, E.L.; Kuhn, P.; Potter, P.M.; Redinbo, M.R.; /North Carolina U. /St. Jude Children's Hosp., Memphis /SLAC, SSRL

    2007-01-16

    Human carboxylesterase 1 (hCE1) is a drug and endobiotic-processing serine hydrolase that exhibits relatively broad substrate specificity. It has been implicated in a variety of endogenous cholesterol metabolism pathways including the following apparently disparate reactions: cholesterol ester hydrolysis (CEH), fatty acyl Coenzyme A hydrolysis (FACoAH), acyl-Coenzyme A:cholesterol acyltransfer (ACAT), and fatty acyl ethyl ester synthesis (FAEES). The structural basis for the ability of hCE1 to perform these catalytic actions involving large substrates and products has remained unclear. Here we present four crystal structures of the hCE1 glycoprotein in complexes with the following endogenous substrates or substrate analogues: Coenzyme A, the fatty acid palmitate, and the bile acids cholate and taurocholate. While the active site of hCE1 was known to be promiscuous and capable of interacting with a variety of chemically distinct ligands, these structures reveal that the enzyme contains two additional ligand-binding sites and that each site also exhibits relatively non-specific ligand-binding properties. Using this multisite promiscuity, hCE1 appears structurally capable of assembling several catalytic events depending, apparently, on the physiological state of the cellular environment. These results expand our understanding of enzyme promiscuity and indicate that, in the case of hCE1, multiple non-specific sites are employed to perform distinct catalytic actions.

  13. Multisite and multivariable statistical downscaling using a Gaussian copula quantile regression model

    NASA Astrophysics Data System (ADS)

    Ben Alaya, M. A.; Chebana, F.; Ouarda, T. B. M. J.

    2016-09-01

    Statistical downscaling techniques are required to refine atmosphere-ocean global climate data and provide reliable meteorological information such as a realistic temporal variability and relationships between sites and variables in a changing climate. To this end, the present paper introduces a modular structure combining two statistical tools of increasing interest during the last years: (1) Gaussian copula and (2) quantile regression. The quantile regression tool is employed to specify the entire conditional distribution of downscaled variables and to address the limitations of traditional regression-based approaches whereas the Gaussian copula is performed to describe and preserve the dependence between both variables and sites. A case study based on precipitation and maximum and minimum temperatures from the province of Quebec, Canada, is used to evaluate the performance of the proposed model. Obtained results suggest that this approach is capable of generating series with realistic correlation structures and temporal variability. Furthermore, the proposed model performed better than a classical multisite multivariate statistical downscaling model for most evaluation criteria.

  14. Listserv use enhances quality and safety in multisite quality improvement efforts.

    PubMed

    Neily, Julia; Mills, Peter D; Surott-Kimberly, B C; Weeks, William Brinson

    2004-01-01

    A listserv is an e-mail group to which people subscribe based upon common interests. We used a retrospective study to examine the relationship between listserv use and team success for health care quality improvement efforts. We hypothesized high listserv use would be associated with team success. Eighty-seven Department of Veterans Affairs teams participated in facilitated quality improvement efforts to address three areas: improving safety in high-hazard areas, improving the disability evaluation process, and reducing falls and related injuries. We coded messages sent to the listserv according to sender (faculty or participant), team, and content. We correlated the volume of messages sent per team with team success and with team and facility characteristics. Teams with high listserv contributions were more likely to complete their first test of change, report facility use of nonpunitive methods of investigating medical incidents, and report their information systems were useful. We found a negative correlation between listserv contribution and the number of face-to-face meetings and a physician as an active team member, but we found no relationship between team success and listserv contribution. Team listserv contribution was not associated with team success in multisite quality improvement efforts. Successful teams may be accessing information on the listserv but not sending a message to indicate use.

  15. Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction.

    PubMed

    Hardy, Tara; Lee, Miseon; Hames, Rebecca S; Prosser, Suzanna L; Cheary, Donna-Marie; Samant, Mugdha D; Schultz, Francisca; Baxter, Joanne E; Rhee, Kunsoo; Fry, Andrew M

    2014-06-01

    During mitotic entry, centrosomes separate to establish the bipolar spindle. Delays in centrosome separation can perturb chromosome segregation and promote genetic instability. However, interphase centrosomes are physically tethered by a proteinaceous linker composed of C-Nap1 (also known as CEP250) and the filamentous protein rootletin. Linker disassembly occurs at the onset of mitosis in a process known as centrosome disjunction and is triggered by the Nek2-dependent phosphorylation of C-Nap1. However, the mechanistic consequences of C-Nap1 phosphorylation are unknown. Here, we demonstrate that Nek2 phosphorylates multiple residues within the C-terminal domain of C-Nap1 and, collectively, these phosphorylation events lead to loss of oligomerization and centrosome association. Mutations in non-phosphorylatable residues that make the domain more acidic are sufficient to release C-Nap1 from the centrosome, suggesting that it is an increase in overall negative charge that is required for this process. Importantly, phosphorylation of C-Nap1 also perturbs interaction with the core centriolar protein, Cep135, and interaction of endogenous C-Nap1 and Cep135 proteins is specifically lost in mitosis. We therefore propose that multisite phosphorylation of C-Nap1 by Nek2 perturbs both oligomerization and Cep135 interaction, and this precipitates centrosome disjunction at the onset of mitosis. PMID:24695856

  16. User Satisfaction Evaluation of the EHR4CR Query Builder: A Multisite Patient Count Cohort System

    PubMed Central

    Soto-Rey, Iñaki; N'Dja, Aurèle; Cunningham, James; Newe, Axel; Trinczek, Benjamin; Lafitte, Caroline; Sedlmayr, Brita; Fritz, Fleur

    2015-01-01

    The Electronic Health Records for Clinical Research (EHR4CR) project aims to develop services and technology for the leverage reuse of Electronic Health Records with the purpose of improving the efficiency of clinical research processes. A pilot program was implemented to generate evidence of the value of using the EHR4CR platform. The user acceptance of the platform is a key success factor in driving the adoption of the EHR4CR platform; thus, it was decided to evaluate the user satisfaction. In this paper, we present the results of a user satisfaction evaluation for the EHR4CR multisite patient count cohort system. This study examined the ability of testers (n = 22 and n = 16 from 5 countries) to perform three main tasks (around 20 minutes per task), after a 30-minute period of self-training. The System Usability Scale score obtained was 55.83 (SD: 15.37), indicating a moderate user satisfaction. The responses to an additional satisfaction questionnaire were positive about the design of the interface and the required procedure to design a query. Nevertheless, the most complex of the three tasks proposed in this test was rated as difficult, indicating a need to improve the system regarding complicated queries. PMID:26539525

  17. Evaluation of Speech-Perception Training for Hearing Aid Users: A Multisite Study in Progress.

    PubMed

    Miller, James D; Watson, Charles S; Dubno, Judy R; Leek, Marjorie R

    2015-11-01

    Following an overview of theoretical issues in speech-perception training and of previous efforts to enhance hearing aid use through training, a multisite study, designed to evaluate the efficacy of two types of computerized speech-perception training for adults who use hearing aids, is described. One training method focuses on the identification of 109 syllable constituents (45 onsets, 28 nuclei, and 36 codas) in quiet and in noise, and on the perception of words in sentences presented in various levels of noise. In a second type of training, participants listen to 6- to 7-minute narratives in noise and are asked several questions about each narrative. Two groups of listeners are trained, each using one of these types of training, performed in a laboratory setting. The training for both groups is preceded and followed by a series of speech-perception tests. Subjects listen in a sound field while wearing their hearing aids at their usual settings. The training continues over 15 to 20 visits, with subjects completing at least 30 hours of focused training with one of the two methods. The two types of training are described in detail, together with a summary of other perceptual and cognitive measures obtained from all participants. PMID:27587914

  18. Computerized ambulatory monitoring in psychiatry: a multi-site collaborative study of acceptability, compliance, and reactivity.

    PubMed

    Johnson, Elizabeth I; Grondin, Olivier; Barrault, Marion; Faytout, Malika; Helbig, Sylvia; Husky, Mathilde; Granholm, Eric L; Loh, Catherine; Nadeau, Louise; Wittchen, Hans-Ulrich; Swendsen, Joel

    2009-01-01

    Computerized ambulatory monitoring overcomes a number of methodological and conceptual challenges to studying mental disorders, however concerns persist regarding the feasibility of this approach with severe psychiatric samples and the potential of intensive monitoring to influence data quality. This multi-site investigation evaluates these issues in four independent samples. Patients with schizophrenia (n = 56), substance dependence (n = 85), anxiety disorders (n = 45), and a non-clinical sample (n = 280) were contacted to participate in investigations using computerized ambulatory monitoring. Micro-computers were used to administer electronic interviews several times per day for a one-week period. Ninety-five percent of contacted individuals agreed to participate in the study, and minimum compliance was achieved by 96% of these participants. Seventy-eight percent of all programmed assessments were completed overall, and only 1% of micro-computers were not returned to investigators. There was no evidence that missing data or response time increased over the duration of the study, suggesting that fatigue effects were negligible. The majority of variables investigated did not change in frequency as a function of study duration, however some evidence was found that socially sensitive behaviors changed in a manner consistent with reactivity.

  19. Magnetospheric accretion onto the T Tauri star AA Tauri. I. Constraints from multisite spectrophotometric monitoring

    NASA Astrophysics Data System (ADS)

    Bouvier, J.; Chelli, A.; Allain, S.; Carrasco, L.; Costero, R.; Cruz-Gonzalez, I.; Dougados, C.; Fernández, M.; Martín, E. L.; Ménard, F.; Mennessier, C.; Mujica, R.; Recillas, E.; Salas, L.; Schmidt, G.; Wichmann, R.

    1999-09-01

    We have monitored the photometric, spectroscopic and polarimetric variations of the classical T Tauri star (CTTS) AA Tau over a period of a month. The light curve consists of more than 260 measurements in each of the B and V-bands over a continuous time period of 30 days and more than 180 measurements in the R and I-bands. This provides unprecedented detail of the photometric variations of a CTTS on timescales ranging from hours to weeks. We find that AA Tau's light curve is quite unlike that of most other CTTS. It exhibits a roughly constant brightness level, interrupted by quasi-cyclic fading episodes with an amplitude of 1.4 mag in BVRI filters. We interpret this behaviour as resulting from quasi-periodic occultations of the stellar photosphere by opaque circumstellar material. The interpretation derives from the lack of significant color variations associated with the fading of the system and is strengthened by the higher polarization level measured when the system is faint. We argue that the occultations are produced by a warp in AA Tau's inner disk which presumably results from the dynamical interaction between the disk and the stellar magnetosphere. We present a model that accounts for the observations quite naturally if we assume that the stellar magnetosphere is a large-scale dipole tilted onto the stellar rotational axis which disrupts the disk at the corotation radius. We derive the geometrical properties of AA Tau's accretion zone in the framework of this model and constrain the location of veiling and Balmer line emitting regions. Although AA Tau's light curve is atypical, the constraints derived here on the structure of its accretion zone may apply as well to other CTTS. It is probably only because AA Tau is seen at a peculiar inclination, close to edge-on, that occultations are conspicuous and its photometric behaviour so clearly reveals this phenomenon. Based on observations obtained at Haute-Provence and Pic du Midi Observatories (France), San

  20. Soft tissue imaging with photon counting spectroscopic CT

    NASA Astrophysics Data System (ADS)

    Shikhaliev, Polad M.

    2015-03-01

    The purpose of this work was experimental investigation of photon counting spectroscopic CT (PCS-CT) imaging of anatomical soft tissue with clinically relevant size. The imaging experiments were performed using a spectroscopic CT system based on CdZnTe photon counting detector with two rows of pixels, 256 pixels in each row, 1  ×  1 mm2 pixel size, and 25.6 cm detector length. The detector could split the x-ray energy spectrum to 5 regions (energy bins), and acquire 5 multi-energy (spectroscopic) CT images in a single CT scan. A sample of round shaped anatomical soft tissue of 14 cm diameter including lean and fat was used for imaging. To avoid the negative effect of anatomical noise on quantitative analysis, a spectroscopic CT phantom with tissue equivalent solid materials was used. The images were acquired at 60, 90, and 120 kVp tube voltages, and spectroscopic image series were acquired with 3 and 5 energy bins. Spectroscopic CT numbers were introduced and used to evaluate an energy selective image series. The anatomical soft tissue with 14 cm diameter was visualized with good quality and without substantial artifacts by the photon counting spectroscopic CT system. The effects of the energy bin crosstalk on spectroscopic CT numbers were quantified and analyzed. The single and double slice PCS-CT images were acquired and compared. Several new findings were observed, including the effect of soft tissue non-uniformity on image artifacts, unique status of highest energy bin, and material dependent visualization in spectroscopic image series. Fat-lean decomposition was performed using dual energy subtraction and threshold segmentation methods, and compared. Using K-edge filtered x-rays improved fat-lean decomposition as compared to conventional x-rays. Several new and important aspects of the PCS-CT were investigated. These include imaging soft tissue with clinically relevant size, single- and double-slice PCS-CT imaging, using spectroscopic CT

  1. Ground-based search for the brightest transiting planets with the Multi-site All-Sky CAmeRA: MASCARA

    NASA Astrophysics Data System (ADS)

    Snellen, Ignas A. G.; Stuik, Remko; Navarro, Ramon; Bettonvil, Felix; Kenworthy, Matthew; de Mooij, Ernst; Otten, Gilles; ter Horst, Rik; le Poole, Rudolf

    2012-09-01

    The Multi-site All-sky CAmeRA MASCARA is an instrument concept consisting of several stations across the globe, with each station containing a battery of low-cost cameras to monitor the near-entire sky at each location. Once all stations have been installed, MASCARA will be able to provide a nearly 24-hr coverage of the complete dark sky, down to magnitude 8, at sub-minute cadence. Its purpose is to find the brightest transiting exoplanet systems, expected in the V=4-8 magnitude range - currently not probed by space- or ground-based surveys. The bright/nearby transiting planet systems, which MASCARA will discover, will be the key targets for detailed planet atmosphere observations. We present studies on the initial design of a MASCARA station, including the camera housing, domes, and computer equipment, and on the photometric stability of low-cost cameras showing that a precision of 0.3-1% per hour can be readily achieved. We plan to roll out the first MASCARA station before the end of 2013. A 5-station MASCARA can within two years discover up to a dozen of the brightest transiting planet systems in the sky.

  2. A spectroscopic investigation of MU SGR

    NASA Astrophysics Data System (ADS)

    Leediarv, L.

    The results of a spectroscopic study of the binary star Mu Sgr are presented. The spectroscopic observations were carried out using the coude spectrograph attached to the two-meter reflecting telescope at the Bulgarian Astronomical Observatory. Additional photometric data were obtained using the S2/68 telescope on board the TD-1 satellite. The microturbulent velocities and the chemical composition of the atmosphere of the primary component of Mu Sgr were determined according to a growth curve, and the results were found to agree with the observations of Kohl (1932). The color excess E(B-V) was equal to about 0.32 mag, and the magnitude in violet was about 7.8 mag. The radius of the primary component is estimated to be about 105 solar radius, based on the Blackwell-Shallis (1977) method. On the basis of the spectrophotometric data, it is concluded that Mu Sgr should be classified in the B6 spectral class, instead of the B8 class as proposed by Barlow and Cohen (1977).

  3. EPSILON AURIGAE: AN IMPROVED SPECTROSCOPIC ORBITAL SOLUTION

    SciTech Connect

    Stefanik, Robert P.; Torres, Guillermo; Lovegrove, Justin; Latham, David W.; Zajac, Joseph; Pera, Vivian E.; Mazeh, Tsevi

    2010-03-15

    A rare eclipse of the mysterious object {epsilon} Aurigae will occur in 2009-2011. We report an updated single-lined spectroscopic solution for the orbit of the primary star based on 20 years of monitoring at the CfA, combined with historical velocity observations dating back to 1897. There are 518 new CfA observations obtained between 1989 and 2009. Two solutions are presented. One uses the velocities outside the eclipse phases together with mid-times of previous eclipses, from photometry dating back to 1842, which provide the strongest constraint on the ephemeris. This yields a period of 9896.0 {+-} 1.6 days (27.0938 {+-} 0.0044 years) with a velocity semi-amplitude of 13.84 {+-} 0.23 km s{sup -1} and an eccentricity of 0.227 {+-} 0.011. The middle of the current ongoing eclipse predicted by this combined fit is JD 2,455,413.8 {+-} 4.8, corresponding to 2010 August 5. If we use only the radial velocities, we find that the predicted middle of the current eclipse is nine months earlier. This would imply that the gravitating companion is not the same as the eclipsing object. Alternatively, the purely spectroscopic solution may be biased by perturbations in the velocities due to the short-period oscillations of the supergiant.

  4. Synergies between spectroscopic and asteroseismic surveys

    NASA Astrophysics Data System (ADS)

    Fu, Jianning; De Cat, Peter; Ren, An-Bing; Yang, Xiao-Hu; Catanzaro, Giovanni; Corbally, Christopher J.; Frasca, Antonio; Gray, Richard O.; Cecylia Molenda-Zakowicz, Joanna; Shi, Jian-Rong; Ali, Luo; Zhang, Haotong

    2015-08-01

    The NASA Kepler satellite has provided unprecedented high duty-cycle, high-precision light curves for a large number of stars by continuously monitoring a field of view in Cygnus-Lyra region, leading to great progress in both discovering exoplanets and characterizing planet-hosting stars by means of asteroseismic methods. The asteroseismic survey allows the investigation of stars covering the whole H-R diagram. However, the low precision of effective temperatures and surface gravities in the KIC10 catalogue and the lack of information on chemical composition, metallicity and rotation rate prevent asteroseismic modeling, requiring spectroscopic observations for thousands of asteroseismic targets in the Kepler field in a homogeneous way.In 2010, we initiated the LAMOST-Kepler project which aimed at collecting low-resolution spectra for as many objects from the KIC10 catalogue as possible, with the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST), a 4-m telescope equipped with 4,000 optical fibers. The first round of observations has been completed in fall 2014, covering all the 14 sub-fields at least once, resulting in more than 100,000 low-resolution spectra. The stellar atmospheric parameters are then derived and the results have been confirmed to be consistent with those reported in the literature based on high-resolution spectroscopy.

  5. sick: The Spectroscopic Inference Crank

    NASA Astrophysics Data System (ADS)

    Casey, Andrew R.

    2016-03-01

    There exists an inordinate amount of spectral data in both public and private astronomical archives that remain severely under-utilized. The lack of reliable open-source tools for analyzing large volumes of spectra contributes to this situation, which is poised to worsen as large surveys successively release orders of magnitude more spectra. In this article I introduce sick, the spectroscopic inference crank, a flexible and fast Bayesian tool for inferring astrophysical parameters from spectra. sick is agnostic to the wavelength coverage, resolving power, or general data format, allowing any user to easily construct a generative model for their data, regardless of its source. sick can be used to provide a nearest-neighbor estimate of model parameters, a numerically optimized point estimate, or full Markov Chain Monte Carlo sampling of the posterior probability distributions. This generality empowers any astronomer to capitalize on the plethora of published synthetic and observed spectra, and make precise inferences for a host of astrophysical (and nuisance) quantities. Model intensities can be reliably approximated from existing grids of synthetic or observed spectra using linear multi-dimensional interpolation, or a Cannon-based model. Additional phenomena that transform the data (e.g., redshift, rotational broadening, continuum, spectral resolution) are incorporated as free parameters and can be marginalized away. Outlier pixels (e.g., cosmic rays or poorly modeled regimes) can be treated with a Gaussian mixture model, and a noise model is included to account for systematically underestimated variance. Combining these phenomena into a scalar-justified, quantitative model permits precise inferences with credible uncertainties on noisy data. I describe the common model features, the implementation details, and the default behavior, which is balanced to be suitable for most astronomical applications. Using a forward model on low-resolution, high signal

  6. Spectroscopic study of sprites

    NASA Astrophysics Data System (ADS)

    Kanmae, Takeshi

    Optical emissions from sprites--large electric discharges in the mesosphere caused by intense lightning strokes--have been studied for decades. Studies have identified that sprite emissions are primarily composed of molecular band emissions of nitrogen and notably identified the near ultraviolet and blue emission from the N2+ First Negative system, which provided direct evidence of ionization in sprites. This implies that further evidence of the ionization may be provided by the visible and near infrared emission from the N2+ Meinel system, which is more accessible from ground-based platforms, though anticipated strong quenching in the mesosphere and below have made the presence of the emission somewhat controversial. To investigate the presence of the Meinel emission along the vertical extent of sprites, we made ground-based spectral observations in 2005. The observed spectra were mainly composed of the N2 First Positive system, and no or little indication of the Meinel bands were found. This study suggests that the quenching is indeed severe at sprite altitude, and it is difficult to study the ionization process in sprites via the Meinel emission. In addition, the data allowed us to investigate details of the First Positive emission from sprites. The observed First Positive spectra showed that the vibrational distribution of the upper state varies along the vertical extent of sprites, which is in agreement with previous reports, and furthermore this study indicates that the variation is associated with altitude, implying that collisional energy transfer processes play roles in exciting the First Positive emission, particularly at lower altitudes. Recent high-speed imaging observations have revealed the very dynamic nature of sprites: they develop within a few to 10 ms in forms of streamers and columnar glows. The underlying electron energies in these features have been inferred from their emissions in previous measurements, but they lacked either sufficient

  7. Spectroscopic Classification of ASASSN-15tx as a CV

    NASA Astrophysics Data System (ADS)

    Bersier, D.; Copperwheat, C.

    2015-12-01

    We report a spectroscopic observation of ASASSN-15tx (ATel #8400) obtained with the 2m robotic Liverpool Telescope (+SPRAT low-resolution spectrograph) on 2015 Dec 11.9078 UT. The spectrum, covering the 400-800 nm range, is blue and nearly featureless.

  8. Spectroscopic Classifications of Optical Transients with SOAR/Goodman

    NASA Astrophysics Data System (ADS)

    Miller, J. A.; Hounsell, R. A.; Pan, Y.-C.; Kilpatrick, C. D.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    We report a classification of optical transients from spectroscopic observations with the Goodman spectrograph on the SOAR telescope. Targets were supplied by the All-Sky Automated Survey for Supernovae (ASAS-SN) and the Pan-STARRS Survey for Transients (PSST).

  9. Spectroscopic Classifications of Optical Transients with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-06-01

    We report the following classifications of optical transients from spectroscopic observations with KOSMOS on the KPNO Mayall 4-m telescope. Targets were supplied by the Pan-STARRS Survey for Transients (PSST), All-Sky Automated Survey for Supernovae (ASAS-SN) and MASTER.

  10. Spectroscopic Classifications of Optical Transients with Mayall/KOSMOS

    NASA Astrophysics Data System (ADS)

    Pan, Y.-C.; Kilpatrick, C. D.; Siebert, M. R.; Foley, R. J.; Jha, S. W.; Rest, A.; Scolnic, D.

    2016-08-01

    We report the following classifications of optical transients from spectroscopic observations with KOSMOS on the KPNO Mayall 4-m telescope. Targets were supplied by the Pan-STARRS Survey for Transients (PSST) and the All-Sky Automated Survey for Supernovae (ASAS-SN).

  11. Spectroscopic Classification of ASASSN-16bx and ASASSN-16cy

    NASA Astrophysics Data System (ADS)

    Frank, S.; Prieto, J. L.; Stanek, K. Z.

    2016-03-01

    We report optical spectroscopic observations of ASASSN-16bx (ATel #8712) and ASASSN-16cy (ATel #8801) obtained by S. Frank on UT 2016 March 14-15 with OSMOS (range 398-686 nm) mounted on the MDM 2.4m telescope at KPNO.

  12. NIST laboratory program on atomic spectroscopic data for astronomy

    NASA Astrophysics Data System (ADS)

    Martin, W. C.; Dalton, G. R.; Fuhr, J. R.; Kelleher, D. E.; Kramida, A.; Mohr, P. J.; Musgrove, A.; Reader, J.; Saloman, E. B.; Sansonetti, C. J.; Sugar, J.; Wiersma, G. G.; Wiese, W. L.; Zucker, D.; Blaise, J.; Wyart, J.-F.; Eichhorn, G.; Grant, C. S.

    Our research program includes the observation and energy-level analysis of several heavy-element spectra of astrophysical interest, as well as the experimental determination of transition probabilities for numerous lines of C I, N I, N II, and O II. Current NIST work on critical compilation of atomic spectroscopic data and on electronic databases is also outlined (37 Refs.)

  13. Multimodal Spectroscopic Study of Amyloid Fibril Polymorphism.

    PubMed

    VandenAkker, Corianne C; Schleeger, Michael; Bruinen, Anne L; Deckert-Gaudig, Tanja; Velikov, Krassimir P; Heeren, Ron M A; Deckert, Volker; Bonn, Mischa; Koenderink, Gijsje H

    2016-09-01

    Amyloid fibrils are a large class of self-assembled protein aggregates that are formed from unstructured peptides and unfolded proteins. The fibrils are characterized by a universal β-sheet core stabilized by hydrogen bonds, but the molecular structure of the peptide subunits exposed on the fibril surface is variable. Here we show that multimodal spectroscopy using a range of bulk- and surface-sensitive techniques provides a powerful way to dissect variations in the molecular structure of polymorphic amyloid fibrils. As a model system, we use fibrils formed by the milk protein β-lactoglobulin, whose morphology can be tuned by varying the protein concentration during formation. We investigate the differences in the molecular structure and composition between long, straight fibrils versus short, wormlike fibrils. We show using mass spectrometry that the peptide composition of the two fibril types is similar. The overall molecular structure of the fibrils probed with various bulk-sensitive spectroscopic techniques shows a dominant contribution of the β-sheet core but no difference in structure between straight and wormlike fibrils. However, when probing specifically the surface of the fibrils with nanometer resolution using tip-enhanced Raman spectroscopy (TERS), we find that both fibril types exhibit a heterogeneous surface structure with mainly unordered or α-helical structures and that the surface of long, straight fibrils contains markedly more β-sheet structure than the surface of short, wormlike fibrils. This finding is consistent with previous surface-specific vibrational sum-frequency generation (VSFG) spectroscopic results ( VandenAkker et al. J. Am. Chem. Soc. , 2011 , 133 , 18030 - 18033 , DOI: 10.1021/ja206513r ). In conclusion, only advanced vibrational spectroscopic techniques sensitive to surface structure such as TERS and VSFG are able to reveal the difference in structure that underlies the distinct morphology and rigidity of different amyloid

  14. Galaxy And Mass Assembly (GAMA): spectroscopic analysis

    NASA Astrophysics Data System (ADS)

    Hopkins, A. M.; Driver, S. P.; Brough, S.; Owers, M. S.; Bauer, A. E.; Gunawardhana, M. L. P.; Cluver, M. E.; Colless, M.; Foster, C.; Lara-López, M. A.; Roseboom, I.; Sharp, R.; Steele, O.; Thomas, D.; Baldry, I. K.; Brown, M. J. I.; Liske, J.; Norberg, P.; Robotham, A. S. G.; Bamford, S.; Bland-Hawthorn, J.; Drinkwater, M. J.; Loveday, J.; Meyer, M.; Peacock, J. A.; Tuffs, R.; Agius, N.; Alpaslan, M.; Andrae, E.; Cameron, E.; Cole, S.; Ching, J. H. Y.; Christodoulou, L.; Conselice, C.; Croom, S.; Cross, N. J. G.; De Propris, R.; Delhaize, J.; Dunne, L.; Eales, S.; Ellis, S.; Frenk, C. S.; Graham, Alister W.; Grootes, M. W.; Häußler, B.; Heymans, C.; Hill, D.; Hoyle, B.; Hudson, M.; Jarvis, M.; Johansson, J.; Jones, D. H.; van Kampen, E.; Kelvin, L.; Kuijken, K.; López-Sánchez, Á.; Maddox, S.; Madore, B.; Maraston, C.; McNaught-Roberts, T.; Nichol, R. C.; Oliver, S.; Parkinson, H.; Penny, S.; Phillipps, S.; Pimbblet, K. A.; Ponman, T.; Popescu, C. C.; Prescott, M.; Proctor, R.; Sadler, E. M.; Sansom, A. E.; Seibert, M.; Staveley-Smith, L.; Sutherland, W.; Taylor, E.; Van Waerbeke, L.; Vázquez-Mata, J. A.; Warren, S.; Wijesinghe, D. B.; Wild, V.; Wilkins, S.

    2013-04-01

    The Galaxy And Mass Assembly (GAMA) survey is a multiwavelength photometric and spectroscopic survey, using the AAOmega spectrograph on the Anglo-Australian Telescope to obtain spectra for up to ˜300 000 galaxies over 280 deg2, to a limiting magnitude of rpet < 19.8 mag. The target galaxies are distributed over 0 < z ≲ 0.5 with a median redshift of z ≈ 0.2, although the redshift distribution includes a small number of systems, primarily quasars, at higher redshifts, up to and beyond z = 1. The redshift accuracy ranges from σv ≈ 50 km s-1 to σv ≈ 100 km s-1 depending on the signal-to-noise ratio of the spectrum. Here we describe the GAMA spectroscopic reduction and analysis pipeline. We present the steps involved in taking the raw two-dimensional spectroscopic images through to flux-calibrated one-dimensional spectra. The resulting GAMA spectra cover an observed wavelength range of 3750 ≲ λ ≲ 8850 Å at a resolution of R ≈ 1300. The final flux calibration is typically accurate to 10-20 per cent, although the reliability is worse at the extreme wavelength ends, and poorer in the blue than the red. We present details of the measurement of emission and absorption features in the GAMA spectra. These measurements are characterized through a variety of quality control analyses detailing the robustness and reliability of the measurements. We illustrate the quality of the measurements with a brief exploration of elementary emission line properties of the galaxies in the GAMA sample. We demonstrate the luminosity dependence of the Balmer decrement, consistent with previously published results, and explore further how Balmer decrement varies with galaxy mass and redshift. We also investigate the mass and redshift dependencies of the [N II]/Hα versus [O III]/Hβ spectral diagnostic diagram, commonly used to discriminate between star forming and nuclear activity in galaxies.

  15. Spectroscopic Orbits for 15 Late-type Stars

    NASA Astrophysics Data System (ADS)

    Willmarth, Daryl W.; Fekel, Francis C.; Abt, Helmut A.; Pourbaix, Dimitri

    2016-08-01

    Spectroscopic orbital elements are determined for 15 stars with periods from 8 to 6528 days with six orbits computed for the first time. Improved astrometric orbits are computed for two stars and one new orbit is derived. Visual orbits were previously determined for four stars, four stars are members of multiple systems, and five stars have Hipparcos “G” designations or have been resolved by speckle interferometry. For the nine binaries with previous spectroscopic orbits, we determine improved or comparable elements. For HD 28271 and HD 200790, our spectroscopic results support the conclusions of previous authors that the large values of their mass functions and lack of detectable secondary spectrum argue for the secondary in each case being a pair of low-mass dwarfs. The orbits given here may be useful in combination with future interferometric and Gaia satellite observations.

  16. Ab-initio calculations of interactions between Cu adatoms on Cu(1 1 0): Sensitivity of strong multi-site interactions to adatom relaxations

    NASA Astrophysics Data System (ADS)

    Sathiyanarayanan, Rajesh; Einstein, T. L.

    2009-08-01

    We have parameterized the various interactions between Cu adatoms on Cu(1 1 0) using density-functional theory based ab-initio calculations. Our results indicate that in addition to pair interactions, 3-adatom and 4-adatom interactions of significant strengths are present in this system. This further stresses the importance of multi-site interactions in constructing a complete lattice-gas picture. Even though adding these multi-site interactions leads to good convergence in interaction energies, we find that some multi-site interactions are very sensitive to adatom relaxations. This makes the application of a simple lattice-gas picture inadequate for such surfaces. We also parameterize adatom interactions on this surface using the recently developed connector model. The connector model parameterization is as efficient as the parameterization using lattice-gas model. Further, we present diffusion barriers for nearest-neighbor (NN) and next-nearest-neighbor (NNN) hops on this surface.

  17. Control of Pteridium aquilinum: Meta-analysis of a Multi-site Study in the UK

    PubMed Central

    Stewart, Gavin; Cox, Emma; Le Duc, Mike; Pakeman, Robin; Pullin, Andrew; Marrs, Rob

    2008-01-01

    Background and Aims A great deal of money is spent controlling invasive weeds as part of international and national policies. It is essential that the funded treatments work across the region in which the policies operate. We argue that experiments across multiple sites are required to validate these programs as results from single sites may be misleading. Here, the control of Pteridium aquilinum (bracken) is used as a test example to address the following four questions. (1) Does the effectiveness of P. aquilinum-control treatments vary across sites? (2) Is the best treatment identified in previous research (cutting twice per year) consistent at all sites, and if not why not? (3) Is treatment performance related to P. aquilinum rhizome mass, litter cover or litter depth at the various sites? (4) Does successful P. aquilinum control influence species richness? Methods Pteridium aquilinum‐control treatments were monitored for 10 years using six replicated experiments and analysed using meta-analysis. Meta-regressions were used to explore heterogeneity between sites. Key Results The effectiveness of treatments varied between sites depending on the measure used to assess P. aquilinum performance. In general, cutting twice per year was the most successful treatment but on some sites other, less expensive treatments were as good. The effectiveness of treatments at different sites was not related to rhizome mass, but the effectiveness of most applied treatments were inversely related to post-control litter. Effective treatment was also associated with high species richness. Conclusions It is concluded that successful development of national weed control programs requires multi-site experimental approaches. Here, meta-analyses demonstrate that variation in effectiveness between sites could be explained in part by pre-specified variables. Reliance on data from a single site for policy formulation is therefore clearly dangerous. PMID:18337356

  18. Crack Growth Prediction Methodology for Multi-Site Damage: Layered Analysis and Growth During Plasticity

    NASA Technical Reports Server (NTRS)

    James, Mark Anthony

    1999-01-01

    A finite element program has been developed to perform quasi-static, elastic-plastic crack growth simulations. The model provides a general framework for mixed-mode I/II elastic-plastic fracture analysis using small strain assumptions and plane stress, plane strain, and axisymmetric finite elements. Cracks are modeled explicitly in the mesh. As the cracks propagate, automatic remeshing algorithms delete the mesh local to the crack tip, extend the crack, and build a new mesh around the new tip. State variable mapping algorithms transfer stresses and displacements from the old mesh to the new mesh. The von Mises material model is implemented in the context of a non-linear Newton solution scheme. The fracture criterion is the critical crack tip opening displacement, and crack direction is predicted by the maximum tensile stress criterion at the crack tip. The implementation can accommodate multiple curving and interacting cracks. An additional fracture algorithm based on nodal release can be used to simulate fracture along a horizontal plane of symmetry. A core of plane strain elements can be used with the nodal release algorithm to simulate the triaxial state of stress near the crack tip. Verification and validation studies compare analysis results with experimental data and published three-dimensional analysis results. Fracture predictions using nodal release for compact tension, middle-crack tension, and multi-site damage test specimens produced accurate results for residual strength and link-up loads. Curving crack predictions using remeshing/mapping were compared with experimental data for an Arcan mixed-mode specimen. Loading angles from 0 degrees to 90 degrees were analyzed. The maximum tensile stress criterion was able to predict the crack direction and path for all loading angles in which the material failed in tension. Residual strength was also accurately predicted for these cases.

  19. Brief interventions to reduce Ecstasy use: a multi-site randomized controlled trial.

    PubMed

    Norberg, Melissa M; Hides, Leanne; Olivier, Jake; Khawar, Laila; McKetin, Rebecca; Copeland, Jan

    2014-11-01

    Studies examining the ability of motivational enhancement therapy (MET) to augment education provision among ecstasy users have produced mixed results and none have examined whether treatment fidelity was related to ecstasy use outcomes. The primary objectives of this multi-site, parallel, two-group randomized controlled trial were to determine if a single-session of MET could instill greater commitment to change and reduce ecstasy use and related problems more so than an education-only intervention and whether MET sessions delivered with higher treatment fidelity are associated with better outcomes. The secondary objective was to assess participants' satisfaction with their assigned interventions. Participants (N=174; Mage=23.62) at two Australian universities were allocated randomly to receive a 15-minute educational session on ecstasy use (n=85) or a 50-minute session of MET that included an educational component (n=89). Primary outcomes were assessed at baseline, and then at 4-, 16-, and 24-weeks postbaseline, while the secondary outcome measure was assessed 4-weeks postbaseline by researchers blind to treatment allocation. Overall, the treatment fidelity was acceptable to good in the MET condition. There were no statistical differences at follow-up between the groups on the primary outcomes of ecstasy use, ecstasy-related problems, and commitment to change. Both intervention groups reported a 50% reduction in their ecstasy use and a 20% reduction in the severity of their ecstasy-related problems at the 24-week follow up. Commitment to change slightly improved for both groups (9%-17%). Despite the lack of between-group statistical differences on primary outcomes, participants who received a single session of MET were slightly more satisfied with their intervention than those who received education only. MI fidelity was not associated with ecstasy use outcomes. Given these findings, future research should focus on examining mechanisms of change. Such work may

  20. Multi-Site Evidence for Marine Nitrogen Fixation in Mid-Cretaceous Black Shales

    NASA Astrophysics Data System (ADS)

    Yum, J.; Meyers, P. A.; Bernasconi, S.

    2004-12-01

    High concentrations of organic carbon in Cretaceous black shales imply levels of sustained export production of organic matter that are unknown in the modern ocean where marine productivity is usually limited by availability of dissolved nitrate. However, if a mid-water anoxic zone expands upward into the photic zone, then nitrogen-fixing cyanobacteria can flourish. These organisms produce organic matter having an isotopic composition close to atmospheric nitrogen (0 per mil). We have compared the carbon and nitrogen isotopic and total organic carbon compositions of Albian to Santonian black shale sequences from the Demerara Rise in the equatorial Atlantic, the Kerguelan Plateau in the southern Indian Ocean, the Hatteras Rise in the western North Atlantic Ocean, the Angola Basin in the eastern South Atlantic Ocean, and the Cape Verde Rise in the eastern North Atlantic Ocean . Nitrogen isotope compositions that become lighter as organic carbon concentrations increase indicate that organic matter production was enhanced by a consortium of primary producers that included nitrogen-fixers. Expansion of an intensified oxygen minimum zone into the photic zone probably permitted coexistence of algae and of cyanobacteria, the latter functioning best under low-oxygen conditions and not being limited by nitrate availability. Improved preservation of the exported organic matter in an intensified near-surface oxygen minimum zone is implied by C/N ratios that increase to 40 as organic carbon concentrations increase. Periods of wetter climate evidently created periods of increased surface stratification of Cretaceous oceans that led to enhanced cyanobacterial primary productivity, magnified organic matter export, and deposition of the organic-carbon-rich black shales. Our multi-site comparison suggests that climate-related gradients in the degree of surface stratification led to associated gradients in export production of organic matter.

  1. Reliability of neuroanatomical measurements in a multisite longitudinal study of youth at risk for psychosis.

    PubMed

    Cannon, Tyrone D; Sun, Frank; McEwen, Sarah Jacobson; Papademetris, Xenophon; He, George; van Erp, Theo G M; Jacobson, Aron; Bearden, Carrie E; Walker, Elaine; Hu, Xiaoping; Zhou, Lei; Seidman, Larry J; Thermenos, Heidi W; Cornblatt, Barbara; Olvet, Doreen M; Perkins, Diana; Belger, Aysenil; Cadenhead, Kristin; Tsuang, Ming; Mirzakhanian, Heline; Addington, Jean; Frayne, Richard; Woods, Scott W; McGlashan, Thomas H; Constable, R Todd; Qiu, Maolin; Mathalon, Daniel H; Thompson, Paul; Toga, Arthur W

    2014-05-01

    Multisite longitudinal neuroimaging designs are used to identify differential brain structural change associated with onset or progression of disease. The reliability of neuroanatomical measurements over time and across sites is a crucial aspect of power in such studies. Prior work has found that while within-site reliabilities of neuroanatomical measurements are excellent, between-site reliability is generally more modest. Factors that may increase between-site reliability include standardization of scanner platform and sequence parameters and correction for between-scanner variations in gradient nonlinearities. Factors that may improve both between- and within-site reliability include use of registration algorithms that account for individual differences in cortical patterning and shape. In this study 8 healthy volunteers were scanned twice on successive days at 8 sites participating in the North American Prodrome Longitudinal Study (NAPLS). All sites employed 3 Tesla scanners and standardized acquisition parameters. Site accounted for 2 to 30% of the total variance in neuroanatomical measurements. However, site-related variations were trivial (<1%) among sites using the same scanner model and 12-channel coil or when correcting for between-scanner differences in gradient nonlinearity and scaling. Adjusting for individual differences in sulcal-gyral geometries yielded measurements with greater reliabilities than those obtained using an automated approach. Neuroimaging can be performed across multiple sites at the same level of reliability as at a single site, achieving within- and between-site reliabilities of 0.95 or greater for gray matter density in the majority of voxels in the prefrontal and temporal cortical surfaces as well as for the volumes of most subcortical structures. PMID:23982962

  2. L-lactate measures in brain tissue with ceramic-based multisite microelectrodes.

    PubMed

    Burmeister, Jason J; Palmer, Michael; Gerhardt, Greg A

    2005-03-15

    A newly developed multisite array microelectrode for in vivo measurements of L-lactate is presented. The resulting microelectrode is composed of three functional layers. First, Nafion is used to repel interfering electroactive anions, such as ascorbate. Second, L-lactate oxidase immobilized onto the recording sites is used to convert L-lactate to hydrogen peroxide. The H2O2 produced is proportional to L-lactate concentrations and is quantified at the platinum recording sites. Third, a layer of polyurethane is coated over the L-lactate oxidase to adjust the linear range of the microelectrode to one that is compatible with in vivo measurements. This layer reduces the amount of L-lactate that diffuses to the enzyme while not significantly limiting oxygen diffusion. The resulting L-lactate microelectrodes were linear to 20 mM (R2 = 0.997 +/- 0.001) and beyond in some cases with detection limits of 0.078 +/- 0.013 mM (n = 12). The selectivity and response time of these electrodes make them suitable for in vivo measurements in brain tissue. Self-referencing recordings may be utilized to further improve the selectivity of the recordings. However this is not necessary for most applications in the brain, because the resting and stimulated levels of dopamine (DA), norepinephrine (NE), and other potentially interfering cations are two to three orders of magnitude lower than that of in vivo L-lactate, which is in the millimolar range. Preliminary in vivo measures of L-lactate in the brain of anesthetized rats support that the microelectrodes are capable of measuring rapid endogenous changes in vivo. PMID:15681193

  3. Electronic Cigarette Marketing Online: a Multi-Site, Multi-Product Comparison

    PubMed Central

    Sidhu, Anupreet K; Valente, Thomas W

    2015-01-01

    Background Electronic cigarette awareness and use has been increasing rapidly. E-cigarette brands have utilized social networking sites to promote their products, as the growth of the e-cigarette industry has paralleled that of Web 2.0. These online platforms are cost-effective and have unique technological features and user demographics that can be attractive for selective marketing. The popularity of multiple sites also poses a risk of exposure to social networks where e-cigarette brands might not have a presence. Objective To examine the marketing strategies of leading e-cigarette brands on multiple social networking sites, and to identify how affordances of the digital media are used to their advantage. Secondary analyses include determining if any brands are benefitting from site demographics, and exploring cross-site diffusion of marketing content through multi-site users. Methods We collected data from two e-cigarette brands from four social networking sites over approximately 2.5 years. Content analysis is used to search for themes, population targeting, marketing strategies, and cross-site spread of messages. Results Twitter appeared to be the most frequently used social networking site for interacting directly with product users. Facebook supported informational broadcasts, such as announcements regarding political legislation. E-cigarette brands also differed in their approaches to their users, from informal conversations to direct product marketing. Conclusions E-cigarette makers use different strategies to market their product and engage their users. There was no evidence of direct targeting of vulnerable populations, but the affordances of the different sites are exploited to best broadcast context-specific messages. We developed a viable method to study cross-site diffusion, although additional refinement is needed to account for how different types of digital media are used. PMID:27227129

  4. Multisite haplotype on cattle chromosome 3 is associated with quantitative trait locus effects on lactation traits.

    PubMed

    Cohen-Zinder, Miri; Donthu, Ravikiran; Larkin, Denis M; Kumar, Charu Gupta; Rodriguez-Zas, Sandra L; Andropolis, Kalista E; Oliveira, Rosane; Lewin, Harris A

    2011-11-01

    The goal of this study was to identify candidate genes and DNA polymorphisms for quantitative trait loci (QTL) affecting milk yield (MY), fat yield (FY), and protein yield (PY) previously mapped to bovine chromosome 3 (BTA3). To accomplish this, 373 half-siblings sired by three bulls previously shown to be segregating for lactation trait QTL, and 263 additional sires in the U.S. Dairy Bull DNA Repository (DBDR) were genotyped for 2,500 SNPs within a 16.3 Mbp QTL critical region on BTA3. Targeted resequencing of ∼1.8 Mbp within the QTL critical region of one of the QTL heterozygous sires identified additional polymorphisms useful for association studies. Twenty-three single nucleotide polymorphisms (SNPs) within a fine-mapped region were associated with effects on breeding values for MY, FY, or PY in DBDR sires, of which five SNPs were in strong linkage disequilibrium in the population. This multisite haplotype included SNPs located within exons or promoters of four tightly linked genes: RAP1A, ADORA3, OVGP1, and C3H1orf88. An SNP within RAP1A showed strong evidence of a recent selective sweep based on integrated haplotype score and was also associated with breeding value for PY. Because of its known function in alveolar lumen formation in the mammary gland, RAP1A is thus a strong candidate gene for QTL effects on lactation traits. Our results provide a detailed assessment of a QTL region that will be a useful guide for complex traits analysis in humans and other noninbred species.

  5. Spectroscopic Study of Multiple IRAS Galaxies

    NASA Astrophysics Data System (ADS)

    Mickaelian, A. M.; Hovhannisyan, L. R.; Sargsyan, L. A.

    2003-04-01

    Spectroscopic observations by the 2.6 m BAO telescope of IRAS galaxies identified on the basis of the First Byurakan Survey (BIG objects) are reported. Slit spectra were obtained for 16 objects, including components of 7 multiple systems and 2 individual galaxies. The red shifts were measured, and the radial velocities, distances, absolute stellar magnitudes, and infrared and far infrared luminosities were calculated. A diagnostic diagram has been constructed based on the intensity ratios of emission lines and the activity types of the objects have been determined. Two LINERs, five galaxies with composite spectra (Comp, one of which has Sy2 features) and seven HII regions were found. Two objects are ultraluminous IR galaxies (ULIG). It is shown that all the multiple systems are physical pairs or groups. The observed high IR luminosity confirms the view that ULIG/HLIGs may be associated with interactions of galaxies.

  6. Ca(2+)-induced movement of tropomyosin in skeletal muscle thin filaments observed by multi-site FRET.

    PubMed Central

    Bacchiocchi, Corrado; Lehrer, Sherwin S

    2002-01-01

    To obtain information on Ca(2+)-induced tropomyosin (Tm) movement in Ca(2+)-regulated muscle thin filaments, frequency-domain fluorescence energy transfer data were collected between 5-(2-iodoacetyl-amino-ethyl-amino)naphthalene-1-sulfonic acid at Cys-190 of Tm and phalloidin-tetramethylrhodamine B isothiocyanate bound to F-actin. Two models were used to fit the experimental data: an atomic coordinate (AC) model coupled with a search algorithm that varies the position and orientation of Tm on F-actin, and a double Gaussian distance distribution (DD) model. The AC model showed that little or no change in transfer efficiency is to be expected between different sites on F-actin and Tm if Ca(2+) causes azimuthal movement of Tm of the magnitude suggested by structural data (C. Xu, R. Craig, L. Tobacman, R. Horowitz, and W. Lehman. 1999. Biophys. J. 77:985-992). However, Ca(2+) produced a small but significant change in our phase/modulation versus frequency data, showing that changes in lifetime decay can be detected even when a change of the steady-state transfer efficiency is very small. A change in Tm azimuthal position of 17 on the actin filament obtained with the AC model indicates that solution data are in reasonable agreement with EM image reconstruction data. In addition, the data indicate that Tm also appears to rotate about its axis, resulting in a rolling motion over the F-actin surface. The DD model showed that the distance from one of the two chains of Tm to F-actin was mainly affected, further verifying that Ca(2+) causes Tm to roll over the F-actin surface. The width of the distance distributions indicated that the position of Tm in absence and in presence of Ca(2+) is well defined with appreciable local flexibility. PMID:11867466

  7. Spectroscopic enhancement in nanoparticles embedded glasses

    NASA Astrophysics Data System (ADS)

    Sahar, M. R.; Ghoshal, S. K.

    2014-09-01

    This presentation provides an overview of the recent progress in the enhancement of the spectroscopic characteristics of the glass embedded with nanoparticles (NPs). Some of our research activities with few significantly new results are highlighted and facilely analyzed. The science and technology dealing with the manipulation of the physical properties of rare earth doped inorganic glasses by embedding metallic NPs or nanoclusters produce the so-called 'nanoglass'. Meanwhile, the spectroscopic enhancement relates the intensity of the luminescence measured at certain transition. The enhancement which expectedly due to the 'plasmonics wave' (referring to the coherent coupling of photons to free electron oscillations called plasmon) occurs at the interface between a conductor and a dielectric. Plasmonics being an emerging concept in advanced optical material of nanophotonics has given this material the ability to exploit the optical response at nanoscale and opened up a new avenue in metal-based glass optics. There is a vast array of plasmonic NPs concepts yet to be explored, with applications spanning solar cells, (bio) sensing, communications, lasers, solid-state lighting, waveguides, imaging, optical data transfer, display and even bio-medicine. Localized surface plasmon resonance (LSPR) can enhance the optical response of nanoglass by orders of magnitude as observed. The luminescence enhancement and surface enhanced Raman scattering (SERS) are new paradigm of research. The enhancement of luminescence due to the influence of metallic NPs is the recurring theme of this paper.

  8. Spectroscopic enhancement in nanoparticles embedded glasses

    SciTech Connect

    Sahar, M. R. Ghoshal, S. K.

    2014-09-25

    This presentation provides an overview of the recent progress in the enhancement of the spectroscopic characteristics of the glass embedded with nanoparticles (NPs). Some of our research activities with few significantly new results are highlighted and facilely analyzed. The science and technology dealing with the manipulation of the physical properties of rare earth doped inorganic glasses by embedding metallic NPs or nanoclusters produce the so-called 'nanoglass'. Meanwhile, the spectroscopic enhancement relates the intensity of the luminescence measured at certain transition. The enhancement which expectedly due to the 'plasmonics wave' (referring to the coherent coupling of photons to free electron oscillations called plasmon) occurs at the interface between a conductor and a dielectric. Plasmonics being an emerging concept in advanced optical material of nanophotonics has given this material the ability to exploit the optical response at nanoscale and opened up a new avenue in metal-based glass optics. There is a vast array of plasmonic NPs concepts yet to be explored, with applications spanning solar cells, (bio) sensing, communications, lasers, solid-state lighting, waveguides, imaging, optical data transfer, display and even bio-medicine. Localized surface plasmon resonance (LSPR) can enhance the optical response of nanoglass by orders of magnitude as observed. The luminescence enhancement and surface enhanced Raman scattering (SERS) are new paradigm of research. The enhancement of luminescence due to the influence of metallic NPs is the recurring theme of this paper.

  9. From the (1B) Spectroscopic State to the Photochemical Product of the Ultrafast Ring-Opening of 1,3-Cyclohexadiene: A Spectral Observation of the Complete Reaction Path.

    PubMed

    Pemberton, Christine C; Zhang, Yao; Saita, Kenichiro; Kirrander, Adam; Weber, Peter M

    2015-08-20

    All stages of the electrocyclic ring-opening of 1,3-cyclohexadiene (CHD) were observed by time-resolved photoionization-photoelectron spectroscopy. Spectra of the 1B state, previously unobserved using time-resolved methods, were obtained upon optical excitation using ultrashort laser pulses at 4.60 or 4.65 eV, followed by ionization with pulses at 3.81, 3.85, and 4.10 eV, revealing a 1B lifetime of 30 fs. In an experiment using 3.07 eV probe photons and a 4.69 eV pump, we observed a time-sequenced progression of Rydberg states that includes s, p, and d states of the series n = 3 to 6. The sequentiality of the Rydberg signals points to an ionization mechanism that captures the molecule on different points along the reaction path in 2A. A dynamic fit of the Rydberg signals, coupled with MS-CASPT2 calculations, reveals that as the wavepacket moves down the potential energy surface it acquires kinetic energy at a rate of 28 eV/ps before reaching the conical intersection to the 1A ground state. During the reaction, the terminal carbon atoms separate at a speed of 16 Å/ps. A deconvolution of the Rydberg signals from a broad feature assigned to structurally disperse 1,3,5-hexatriene (HT) shows the formation of the open-chain hexatriene structure with an onset 142 fs after the initial absorption of a pump photon. The experimental observations are discussed in the context of recent ultrafast X-ray scattering experiments and theoretical quantum dynamics simulations. PMID:26192201

  10. The 1997 spectroscopic GEISA databank.

    NASA Astrophysics Data System (ADS)

    Jacquinet-Husson, N.; Arie, E.; Ballard, J.; Barbe, A.; Bjoraker, G.; Bonnet, B.; Brown, L. R.; Camy-Peyret, C.; Champion, J. P.; Chedin, A.; Chursin, A.; Clerbaux, C.; Duxbury, G.; Flaud, J.-M.; Fourrie, N.; Fayt, A.; Graner, G.; Gamache, R.; Goldman, A.; Golovko, V.; Guelachvili, G.; Hartmann, J. M.; Hilico, J. C.; Hillman, J.; Lefevre, G.; Lellouch, E.; Mikhailenko, S. N.; Naumenko, O. V.; Nemtchinov, V.; Newnham, D. A.; Nikitin, A.; Orphal, J.; Perrin, A.; Reuter, D. C.; Rinsland, C. P.; Rosenmann, L.; Rothman, L. S.; Scott, N. A.; Selby, J.; Sinitsa, L. N.; Sirota, J. M.; Smith, A. M.; Smith, K. M.; Tyuterev, V. G.; Tipping, R. H.; Urban, S.; Varanasi, P.; Weber, M.

    1999-05-01

    The current version GEISA-97 of the computer-accessible database system GEISA (Gestion et Etude des Informations Spectroscopiques Atmospheriques: Management and Study of Atmospheric Spectroscopic Information) is described. This catalogue contains 1,346,266 entries. These are the spectroscopic parameters required to describe adequately the individual spectral lines belonging to 42 molecules (96 isotopic species) and located between 0 and 22656 cm-1. The featured molecules are of interest in studies of the terrestrial as well as the other planetary atmospheres, especially those of the giant planets. GEISA-97 contains also a catalog of absorption cross-sections of molecules such as chlorofluorocarbons which exhibit unresolvable spectra. The modifications and improvements made to the earlier edition (GEISA-92) and the data management software are described.

  11. Mid-infrared spectroscopic investigation

    NASA Technical Reports Server (NTRS)

    Salisbury, John W.; Vergo, Norma; Walter, Louis

    1987-01-01

    Mid-infrared spectroscopic research efforts are discussed. The development of a new instrumentation to permit advanced measurements in the mid-infrared region of the spectrum, the development of a special library of well-characterized mineral and rock specimens for interpretation of remote sensing data, and cooperative measurements of the spectral signatures of analogues of materials that may be present on the surfaces of asteroids, planets or their Moons are discussed.

  12. Spectroscopic confirmation of the dwarf nova nature of GR Orionis

    NASA Astrophysics Data System (ADS)

    Arai, Akira; Nogami, Daisaku

    2013-02-01

    We spectroscopically observed GR Ori with the 2.0-m Nayuta Telescope at Nishi-Harima Astronomical Observatory on 2013 February 13. This observation was carried out with the low resolution mode (R~1,000) of the optical spectrograph MALLS which covers the wavelength of 4,000-6,800 A. GR Ori was discovered as a possible nova in 1916 (Thiele 1916, Astron. Nachr., 202, 213), but has long been suspected to be a dwarf nova (e.g.

  13. Time-resolved infrared-spectroscopic observation of relaxation and reaction processes during and after infrared-multiphoton excitation of 12CF3I and 13CF3I with shaped nanosecond pulses

    NASA Astrophysics Data System (ADS)

    Quack, Martin; Schwarz, René; Seyfang, Georg

    1992-06-01

    We have produced shaped infrared laser pulses of several kinds ranging from about 2-100 ns duration using a line tuned CO2 laser combined with intracavity absorbers and a CdTe electro-optical switch. The time-dependent infrared absorption of 12CF3I and 13CF3I during and after infrared-multiphoton excitation with these pulses was followed by means of a line tuned continuous wave-CO2 laser and a fast HgCdTe infrared detector (time resolution about 1 ns). The effective time-dependent absorption cross section shows fluence-dependent decay at large fluence with an effective exponential decay constant kI,σ≂1.12 cm2 J-1. This can be interpreted by first generation and then decay by further radiative pumping of highly excited levels of CF3I. The results have been analyzed by master equation modeling using a nonlinear case B/C master equation for multiphoton excitation and very simple models for the absorption properties of highly excited molecules. After nanosecond excitation to very high levels, one finds unimolecular decay CF3I→CF3+I with distinct rate constants (2±1)×108 and (5±4)×106 s-1, which corresponds to ensembles of molecules differing by one CO2 -laser quantum of energy, in agreement with unimolecular rate theory and master equation models. The most striking observation is a slow, collision-free intramolecular rovibrational redistribution process observed by real time spectroscopy on the nanosecond time scale for molecules excited by modest fluence corresponding to typical average energies of five CO2 laser quanta and somewhat more.

  14. Ten Steps to Conducting a Large, Multi-Site, Longitudinal Investigation of Language and Reading in Young Children

    PubMed Central

    Farquharson, Kelly; Murphy, Kimberly A.

    2016-01-01

    Purpose: This paper describes methodological procedures involving execution of a large-scale, multi-site longitudinal study of language and reading comprehension in young children. Researchers in the Language and Reading Research Consortium (LARRC) developed and implemented these procedures to ensure data integrity across multiple sites, schools, and grades. Specifically, major features of our approach, as well as lessons learned, are summarized in 10 steps essential for successful completion of a large-scale longitudinal investigation in early grades. Method: Over 5 years, children in preschool through third grade were administered a battery of 35 higher- and lower-level language, listening, and reading comprehension measures (RCM). Data were collected from children, their teachers, and their parents/guardians at four sites across the United States. Substantial and rigorous effort was aimed toward maintaining consistency in processes and data management across sites for children, assessors, and staff. Conclusion: With appropriate planning, flexibility, and communication strategies in place, LARRC developed and executed a successful multi-site longitudinal research study that will meet its goal of investigating the contribution and role of language skills in the development of children's listening and reading comprehension. Through dissemination of our design strategies and lessons learned, research teams embarking on similar endeavors can be better equipped to anticipate the challenges. PMID:27064308

  15. Facebook as a tool for communication, collaboration, and informal knowledge exchange among members of a multisite family health team

    PubMed Central

    Lofters, Aisha K; Slater, Morgan B; Nicholas Angl, Emily; Leung, Fok-Han

    2016-01-01

    Objective To implement and evaluate a private Facebook group for members of a large Ontario multisite Family Health Team (FHT) to facilitate improved communication and collaboration. Design Program implementation and subsequent survey of team members. Setting A large multisite FHT in Toronto, Ontario. Participants Health professionals of the FHT. Main outcome measures Usage patterns and self-reported perceptions of the Facebook group by team members. Results At the time of the evaluation survey, the Facebook group had 43 members (37.4% of all FHT members). Activity in the group was never high, and posts by team members who were not among the researchers were infrequent throughout the study period. The content of posts fell into two broad categories: 1) information that might be useful to various team members and 2) questions posed by team members that others might be able to answer. Of the 26 team members (22.6%) who completed the evaluation survey, many reported that they never logged into the Facebook page (16 respondents), and never used it to communicate with team members outside of their own site of practice (19 respondents). Only six respondents reported no concerns with using Facebook as a professional communication tool; the most frequent concerns were regarding personal and patient privacy. Conclusion The use of social media by health care practitioners is becoming ubiquitous. However, the issues of privacy concerns and determining how to use social media without adding to provider workload must be addressed to make it a useful tool in health care. PMID:26869796

  16. Spectroscopic properties of UV active medium Ce3+:LiSr0.8Ca0.2AlF6

    NASA Astrophysics Data System (ADS)

    Nizamutdinov, A. S.; Shavelev, A. A.; Marisov, M. A.; Semashko, V. V.

    2016-02-01

    The aim of this work is phase composition and near UV spectroscopic studies of UV active media in fluoride crystals with colquiriite structure, such as Ce3+:LiSr0.8Ca0.2AlF6. Colquiriite structure mixed crystals show higher segregation coefficient of Ce3+ activator ions than common LiCaAlF6 hosts. An important result is based on the fact that this enhancement was achieved for two types of Ce3+ centers in a multisite Ce:LiSr0.8Ca0.2AlF6 system. Thus, it provides a higher gain coefficient for the 5d-4f transitions of Ce3+ ions and it spans a wider continuous wavelength tuning range between 280 and 320 nm for tunable Ce:LiSr0.8Ca0.2AlF6 laser systems.

  17. Acrylonitrile is a multisite carcinogen in male and female B6C3F1 mice.

    PubMed

    Ghanayem, Burhan I; Nyska, Abraham; Haseman, Joseph K; Bucher, John R

    2002-07-01

    Acrylonitrile is a heavily produced unsaturated nitrile, which is used in the production of synthetic fibers, plastics, resins, and rubber. Acrylonitrile is a multisite carcinogen in rats after exposure via gavage, drinking water, or inhalation. No carcinogenicity studies of acrylonitrile in a second animal species were available. The current studies were designed to assess the carcinogenicity of acrylonitrile in B6C3F1 mice of both sexes. Acrylonitrile was administered by gavage at 0, 2.5, 10, or 20 mg/kg/day, 5 days per week, for 2 years. Urinary thiocyanate and N-acetyl-S-(2-cyanoethyl)-L-cysteine were measured as markers of exposure to acrylonitrile. In general, there were dose-related increases in urinary thiocyanate and N-acetyl-S-(2-cyanoethyl)-L-cysteine concentrations in all dosed groups of mice and at all time points. Survival was significantly (p < 0.001) reduced in the top dose (20 mg/kg) group of male and female mice relative to controls. The incidence of forestomach papillomas and carcinomas was increased in mice of both sexes in association with an increase in forestomach epithelial hyperplasia. The incidence of Harderian gland adenomas and carcinomas was also markedly increased in the acrylonitrile-dosed groups. In female mice, the incidence of benign or malignant granulosa cell tumors (combined) in the ovary in the 10 mg/kg dose group was greater than that in the vehicle control group, but because of a lack of dose response, this was considered an equivocal finding. In addition, the incidences of atrophy and cysts in the ovary of the 10 and 20 mg/kg dose groups were significantly increased. The incidences of alveolar/bronchiolar adenoma or carcinoma (combined) were significantly increased in female mice treated with acrylonitrile at 10 mg/kg/day for 2 years. This was also considered an equivocal result. In conclusion, these studies demonstrated that acrylonitrile causes multiple carcinogenic effects after gavage administration to male and female B6

  18. Performance of physician-certified verbal autopsies: multisite validation study using clinical diagnostic gold standards

    PubMed Central

    2011-01-01

    Background Physician review of a verbal autopsy (VA) and completion of a death certificate remains the most widely used approach for VA analysis. This study provides new evidence about the performance of physician-certified verbal autopsy (PCVA) using defined clinical diagnostic criteria as a gold standard for a multisite sample of 12,542 VAs. The study was also designed to analyze issues related to PCVA, such as the impact of a second physician reader on the cause of death assigned, the variation in performance with and without household recall of health care experience (HCE), and the importance of local information for physicians reading VAs. Methods The certification was performed by 24 physicians. The assignment of VA was random and blinded. Each VA was certified by one physician. Half of the VAs were reviewed by a different physician with household recall of health care experience included. The completed death certificate was processed for automated ICD-10 coding of the underlying cause of death. PCVA was compared to gold standard cause of death assignment based on strictly defined clinical diagnostic criteria that are part of the Population Health Metrics Research Consortium (PHMRC) gold standard verbal autopsy study. Results For individual cause assignment, the overall chance-corrected concordance for PCVA against the gold standard cause of death is less than 50%, with substantial variability by cause and physician. Physicians assign the correct cause around 30% of the time without HCE, and addition of HCE improves performance in adults to 45% and slightly higher in children to 48%. Physicians estimate cause-specific mortality fractions (CSMFs) with considerable error for adults, children, and neonates. Only for neonates for a cause list of six causes with HCE is accuracy above 0.7. In all three age groups, CSMF accuracy improves when household recall of health care experience is available. Conclusions Results show that physician coding for cause of death

  19. Random forests for verbal autopsy analysis: multisite validation study using clinical diagnostic gold standards

    PubMed Central

    2011-01-01

    Background Computer-coded verbal autopsy (CCVA) is a promising alternative to the standard approach of physician-certified verbal autopsy (PCVA), because of its high speed, low cost, and reliability. This study introduces a new CCVA technique and validates its performance using defined clinical diagnostic criteria as a gold standard for a multisite sample of 12,542 verbal autopsies (VAs). Methods The Random Forest (RF) Method from machine learning (ML) was adapted to predict cause of death by training random forests to distinguish between each pair of causes, and then combining the results through a novel ranking technique. We assessed quality of the new method at the individual level using chance-corrected concordance and at the population level using cause-specific mortality fraction (CSMF) accuracy as well as linear regression. We also compared the quality of RF to PCVA for all of these metrics. We performed this analysis separately for adult, child, and neonatal VAs. We also assessed the variation in performance with and without household recall of health care experience (HCE). Results For all metrics, for all settings, RF was as good as or better than PCVA, with the exception of a nonsignificantly lower CSMF accuracy for neonates with HCE information. With HCE, the chance-corrected concordance of RF was 3.4 percentage points higher for adults, 3.2 percentage points higher for children, and 1.6 percentage points higher for neonates. The CSMF accuracy was 0.097 higher for adults, 0.097 higher for children, and 0.007 lower for neonates. Without HCE, the chance-corrected concordance of RF was 8.1 percentage points higher than PCVA for adults, 10.2 percentage points higher for children, and 5.9 percentage points higher for neonates. The CSMF accuracy was higher for RF by 0.102 for adults, 0.131 for children, and 0.025 for neonates. Conclusions We found that our RF Method outperformed the PCVA method in terms of chance-corrected concordance and CSMF accuracy for

  20. Spectroscopic study of solar twins and analogues

    NASA Astrophysics Data System (ADS)

    Datson, Juliet; Flynn, Chris; Portinari, Laura

    2015-02-01

    Context. Many large stellar surveys have been and are still being carried out, providing huge amounts of data, for which stellar physical parameters will be derived. Solar twins and analogues provide a means to test the calibration of these stellar catalogues because the Sun is the best-studied star and provides precise fundamental parameters. Solar twins should be centred on the solar values. Aims: This spectroscopic study of solar analogues selected from the Geneva-Copenhagen Survey (GCS) at a resolution of 48 000 provides effective temperatures and metallicities for these stars. We test whether our spectroscopic parameters, as well as the previous photometric calibrations, are properly centred on the Sun. In addition, we search for more solar twins in our sample. Methods: The methods used in this work are based on literature methods for solar twin searches and on methods we developed in previous work to distinguish the metallicity-temperature degeneracies in the differential comparison of spectra of solar analogues versus a reference solar reflection spectrum. Results: We derive spectroscopic parameters for 148 solar analogues (about 70 are new entries to the literature) and verify with a-posteriori differential tests that our values are well-centred on the solar values. We use our dataset to assess the two alternative calibrations of the GCS parameters; our methods favour the latest revision. We show that the choice of spectral line list or the choice of asteroid or time of observation does not affect the results. We also identify seven solar twins in our sample, three of which are published here for the first time. Conclusions: Our methods provide an independent means to differentially test the calibration of stellar catalogues around the values of a well-known benchmark star, which makes our work interesting for calibration tests of upcoming Galactic surveys. Based on observations made with ESO Telescopes at the La Silla Observatory under programme ID 077.D

  1. Asiago spectroscopic classification of ASASSN-16bp

    NASA Astrophysics Data System (ADS)

    Tomasella, L.; Pastorello, A.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Ochner, P.; Tartaglia, L.; Terreran, G.; Turatto, M.

    2016-02-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of ASASSN-16bp ( = AT 2016adq), discovered by All Sky Automated Survey for SuperNovae ASAS-SN (see Shappee et al. 2014, ApJ, 788, 48 and http://www.astronomy.ohio-state.edu/~assassin/index.shtml ), in CGCG 336-041 (Atel #8666) The observation was performed with the Asiago 1.82 m Copernico Telescope (+AFOSC; range 340-820 nm; resolution 1.4 nm). Name | Discovery UT | Obs. Date UT |z | Type | Phase |Notes ASASSN-16bp | 20160209.61 | 20160211.11 |0.034194 | Ia | ~10d | (1) (1) Also known as SN2016adq in CGCG 336-041 (z=0.034194, d=145 Mpc, via NED).

  2. The Development of a Strategic Plan To Provide a Multisite Electronic Engineering Technology Program at the Community College of Allegheny County.

    ERIC Educational Resources Information Center

    Cunningham, Pearly

    A project was undertaken to develop a strategic plan to implement a multisite electronic engineering technology (EET) program at Pennsylvania's Community College of Allegheny County. Specifically, the project sought to determine how electronic communication technologies could provide a virtual learning community for the program; appropriate plans…

  3. Interracial Contact and Racial Constancy: A Multi-Site Study of Racial Intergroup Bias in 3-5 Year Old Anglo-British Children

    ERIC Educational Resources Information Center

    Rutland, Adam; Cameron, Lindsey; Bennett, Laura; Ferrell, Jennifer

    2005-01-01

    This paper examined the influence of interracial contact and racial constancy on the racial intergroup bias of young Anglo-British children. This multi-site study was conducted in areas of Great Britain that varied in terms of racial diversity. The study also investigated whether preschool children express bias on positive, but not negative,…

  4. Sensitivity of the Modified Children's Yale-Brown Obsessive Compulsive Scale to Detect Change: Results from Two Multi-Site Trials

    ERIC Educational Resources Information Center

    Scahill, Lawrence; Sukhodolsky, Denis G.; Anderberg, Emily; Dimitropoulos, Anastasia; Dziura, James; Aman, Michael G.; McCracken, James; Tierney, Elaine; Hallett, Victoria; Katz, Karol; Vitiello, Benedetto; McDougle, Christopher

    2016-01-01

    Repetitive behavior is a core feature of autism spectrum disorder. We used 8-week data from two federally funded, multi-site, randomized trials with risperidone conducted by the Research Units on Pediatric Psychopharmacology Autism Network to evaluate the sensitivity of the Children's Yale-Brown Obsessive Compulsive Scale modified for autism…

  5. WWC Review of the Report "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Randomized Experiment." What Works Clearinghouse Single Study Review

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2015

    2015-01-01

    For the 2013 study, "Transfer Incentives for High-Performing Teachers: Final Results from a Multisite Randomized Experiment," researchers examined the impact of the Talent Transfer Initiative (TTI) on students' reading and mathematics achievement in 10 school districts. The TTI enabled principals of low-performing schools to provide…

  6. The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network

    ERIC Educational Resources Information Center

    Schendel, Diana E.; DiGuiseppi, Carolyn; Croen, Lisa A.; Fallin, M. Daniele; Reed, Philip L.; Schieve, Laura A.; Wiggins, Lisa D.; Daniels, Julie; Grether, Judith; Levy, Susan E.; Miller, Lisa; Newschaffer, Craig; Pinto-Martin, Jennifer; Robinson, Cordelia; Windham, Gayle C.; Alexander, Aimee; Aylsworth, Arthur S.; Bernal, Pilar; Bonner, Joseph D.; Blaskey, Lisa; Bradley, Chyrise; Collins, Jack; Ferretti, Casara J.; Farzadegan, Homayoon; Giarelli, Ellen; Harvey, Marques; Hepburn, Susan; Herr, Matthew; Kaparich, Kristina; Landa, Rebecca; Lee, Li-Ching; Levenseller, Brooke; Meyerer, Stacey; Rahbar, Mohammad H.; Ratchford, Andria; Reynolds, Ann; Rosenberg, Steven; Rusyniak, Julie; Shapira, Stuart K.; Smith, Karen; Souders, Margaret; Thompson, Patrick Aaron; Young, Lisa; Yeargin-Allsopp, Marshalyn

    2012-01-01

    The Study to Explore Early Development (SEED), a multisite investigation addressing knowledge gaps in autism phenotype and etiology, aims to: (1) characterize the autism behavioral phenotype and associated developmental, medical, and behavioral conditions and (2) investigate genetic and environmental risks with emphasis on immunologic, hormonal,…

  7. The Challenges and Benefits of Employing a Mobile Research Fellow to Facilitate Team Work on a Large, Interdisciplinary, Multi-Sited Project

    ERIC Educational Resources Information Center

    Sugden, Fraser; Punch, Samantha

    2014-01-01

    Over the last few years research funding has increasingly moved in favour of large, multi-partner, interdisciplinary and multi-site research projects. This article explores the benefits and challenges of employing a full-time research fellow to work across multiple field sites, with all the local research teams, on an international,…

  8. The Value and Potential of Multisited Ethnography for Science Education Research: A Review of Jrene Rahm's "Science in the Making at the Margin"

    ERIC Educational Resources Information Center

    Beeman-Cadwallader, Nicole

    2012-01-01

    Rahm sought to illuminate how children and youth make meaning of science in three out-of-school time programs, and the identity work that is done through the trajectory of their youth toward their young adulthood. Through using multisited ethnography, she asserts that we can learn more about what the youth say about their science learning and…

  9. The Setting-up of Multi-Site School Collaboratives: The Benefits of This Organizational Reform in Terms of Networking Opportunities and Their Effects

    ERIC Educational Resources Information Center

    Mifsud, Denise

    2015-01-01

    This article, which is set within the Maltese education scenario of unfolding decentralization through the setting-up of multi-site school collaboratives (legally termed "colleges") via a policy mandate, explores a particular aspect of this reform--that of "networking". This is examined in terms of the potential for…

  10. Sources of Site Differences in the Efficacy of a Multisite Clinical Trial: The Treatment of SSRI-Resistant Depression in Adolescents

    ERIC Educational Resources Information Center

    Spirito, Anthony; Abebe, Kaleab Z.; Iyengar, Satish; Brent, David; Vitiello, Benedetto; Clarke, Gregory; Wagner, Karen Dineen; Asarnow, Joan; Emslie, Graham; Keller, Martin

    2009-01-01

    Site differences in treatment outcomes are not often highlighted when the results of multisite randomized clinical trials (MRCTs) are reported. The primary analyses of a 6-site MRCT, the Treatment of SSRI-Resistant Depression in Adolescents (TORDIA) study, showed substantial variation by site in the performance of a medication-only condition and a…

  11. Measurement characteristics of activity-related psychosocial measures in 8- to 10-year-old African-American girls in the Girls health Enrichment Multisite Study (GEMS)

    Technology Transfer Automated Retrieval System (TEKTRAN)

    BACKGROUND: This paper presents reliability and validity analyses of physical activity-related psychosocial questionnaires completed by 8- to 10-year-old African-American girls at baseline and follow-up assessments of pilot intervention studies in the Girls health Enrichment Multi-site Study (GEMS)....

  12. Revealing the ISM in high redshift starburst galaxies: An analysis of Herschel PACS and SPIRE FTS spectroscopic observations of HerMES and H-ATLAS-selected lensed galaxies

    NASA Astrophysics Data System (ADS)

    Cooray, Asantha

    In the quest to develop a fundamental understanding of galaxy formation and evolution, observations of dusty star-forming galaxies (DSFGs) promise significant progress this decade. The importance of DSFGs is highlighted by the fact that half of the energy emitted by extragalactic sources emerges as dust-reprocessed light at infrared (IR) to sub millimeter wavelength. In the post-herschel\\ era, we are now at a unique position to tackle some of the key questions on galaxy formation and evolution because of the large area Herschel's Key Project surveys (HerMES and H-ATLAS). In particular those surveys have allowed us to identify a sample of 250 strongly gravitationally lensed DSFGs at z > 1. They give us a unique opportunity to dissect the detailed structures and kinematics of DSFGs. The Herschel Science Archive also contains individual follow up data on 44 and 25 of the brightest sources with SPIRE-FTS and PACS, respectively, in the spectroscopy mode, taking over 250 hours in four open-time programs. Only one of the 44 SPIRE FTS targets has yet to appear in the published literature. One of the four include an open-time 2 PACS spectroscopy program that was led at UCI by a former postdoc from the PI's group. That program was initially approved at Priority 2 in 2011, but was triggered in late 2012 and achieved 100% completion during the last two weeks of Herschel lifetime in May 2013. This archival analysis, interpretation, and modeling program involves two parts: (i) PACS spectroscopy in 50 to 200 microns of 25 lensed galaxies in the fine-structure emission lines [SiII]34, [SIII]33, [OIV]26, [OIII]52, [NIII]57 and [OI]63, and the molecular hydrogen H_2 S(0) and S(1). (ii) SPIRE FTS spectroscopy of 44 lensed galaxies, including above 25, over the wavelength range of 200 to 600 microns targeting [CII]158, [OIII]88, [OI]63/145, and [NI]122. The analysis will lead to a better understanding of the ISM of starbursting galaxies that span 1 < z < 3.1 range in redshift and a

  13. Predicting Future Space-Based Slitless Spectroscopic Surveys Using the WFC3 Infrared Spectroscopic Parallels (WISP)

    NASA Astrophysics Data System (ADS)

    Colbert, James W.; Teplitz, H.; Malkan, M.; Atek, H.; Ross, N.; Siana, B.; Henry, A.; McCarthy, P.; Bunker, A.; Scarlata, C.

    2012-01-01

    Future space telescopes are likely to make extensive use of slitless grism spectroscopy in the near-IR over large areas of sky. Both ESA's recently selected Euclid mission and the WFIRST mission being studied by NASA plan slitless spectroscopic surveys to obtain redshifts over thousands of square degrees. The HST WFC3 camera has two near-infrared grisms, G102 and G141, covering 0.8-1.6 microns, making it perfect the perfect laboratory for predicting what these future missions will find. We present results from the WFC3 Infrared Spectroscopic Parallels (WISP) program, which has been taking deep WFC3 observations using both grisms at random locations across the sky in parallel with primary COS observations. The WISP survey presently consists of more than 150 fields, covering 700 square arcminutes, reaching fluxes of 5 x 10-17 ergs/s/cm2. We will present completeness corrected number counts, luminosity functions, and predicted counts for the proposed future missions. We will also discuss the issue of line identification of the emission lines, particularly H-alpha and [OIII]5007 which often have similar fluxes and equivalent widths.

  14. Violence and non-violence-related injuries and alcohol in women from developed and developing countries: a multi-site emergency room study.

    PubMed

    da Silva, Rosiane Lopes; Diehl, Alessandra; Cherpitel, Cheryl J; Figlie, Neliana B

    2015-02-01

    This study sought to analyze the association between alcohol consumption and the occurrence of injuries in women attending the emergency room (ER) from developing and developed countries. The sample consisted of ER data from women in 15 countries that were collected as part of two multi-site studies using similar methodologies: the Emergency Room Collaborative Alcohol Analysis Project (ERCAAP), and World Health Organization Collaborative Study on Alcohol and Injuries (WHO Study). Women ranged in age from 18 to 98years. Those from developed countries had higher levels of education (43% completed high-school) than women from developing countries (37%). Over half of the women from developing countries reported they had not consumed alcohol in the last 12months (abstentious), while 2% reported drinking every day. In addition, current drinking women from developing countries reported more binge drinking episodes (33% reported 5 to 11 drinks and 15% reported 12 or more drinks on an occasion) compared to those from developed countries (28% and 11%, respectively). Violence-related injury was more prevalent in developing countries (18%) compared to developed countries (9%). An association between injury and the frequency of alcohol consumption in the last 12months was observed in both developing and developed countries. Although women from developing countries who suffered violence-related injuries were more likely to demonstrate alcohol abstinence or have lower rates of daily alcohol consumption, these women drank in a more dangerous way, and violence-related injuries were more likely to occur in these women than in those living in developed countries.

  15. Spectroscopic signature for ferroelectric ice

    NASA Astrophysics Data System (ADS)

    Wójcik, Marek J.; Gług, Maciej; Boczar, Marek; Boda, Łukasz

    2014-09-01

    Various forms of ice exist within our galaxy. Particularly intriguing type of ice - ‘ferroelectric ice' was discovered experimentally and is stable in temperatures below 72 K. This form of ice can generate enormous electric fields and can play an important role in planetary formation. In this letter we present Car-Parrinello simulation of infrared spectra of ferroelectric ice and compare them with spectra of hexagonal ice. Librational region of the spectra can be treated as spectroscopic signature of ice XI and can be of help to identify ferroelectric ice in the Universe.

  16. The far ultraviolet spectroscopic explorer

    NASA Technical Reports Server (NTRS)

    Boggess, A.

    1982-01-01

    The scientific objectives and performance characteristics of a new astronomy mission referred to as the far ultraviolet spectroscopic explorer, or FUSE are being defined by a team involving people experienced instrumental requirements that best meet the scientific needs. The team is intended to have a lifetime of about one year, ending with the submission of a report to NASA which could be used as the basis for an engineering design study. The principal objective of FUSE is to obtain astronomical spectra at wavelengths shorter than is possible with the Space Telescope.

  17. The GEISA Spectroscopic Database System in its latest Edition

    NASA Astrophysics Data System (ADS)

    Jacquinet-Husson, N.; Crépeau, L.; Capelle, V.; Scott, N. A.; Armante, R.; Chédin, A.

    2009-04-01

    GEISA (Gestion et Etude des Informations Spectroscopiques Atmosphériques: Management and Study of Spectroscopic Information)[1] is a computer-accessible spectroscopic database system, designed to facilitate accurate forward planetary radiative transfer calculations using a line-by-line and layer-by-layer approach. It was initiated in 1976. Currently, GEISA is involved in activities related to the assessment of the capabilities of IASI (Infrared Atmospheric Sounding Interferometer on board the METOP European satellite -http://earth-sciences.cnes.fr/IASI/)) through the GEISA/IASI database[2] derived from GEISA. Since the Metop (http://www.eumetsat.int) launch (October 19th 2006), GEISA/IASI is the reference spectroscopic database for the validation of the level-1 IASI data, using the 4A radiative transfer model[3] (4A/LMD http://ara.lmd.polytechnique.fr; 4A/OP co-developed by LMD and Noveltis with the support of CNES). Also, GEISA is involved in planetary research, i.e.: modelling of Titan's atmosphere, in the comparison with observations performed by Voyager: http://voyager.jpl.nasa.gov/, or by ground-based telescopes, and by the instruments on board the Cassini-Huygens mission: http://www.esa.int/SPECIALS/Cassini-Huygens/index.html. The updated 2008 edition of GEISA (GEISA-08), a system comprising three independent sub-databases devoted, respectively, to line transition parameters, infrared and ultraviolet/visible absorption cross-sections, microphysical and optical properties of atmospheric aerosols, will be described. Spectroscopic parameters quality requirement will be discussed in the context of comparisons between observed or simulated Earth's and other planetary atmosphere spectra. GEISA is implemented on the CNES/CNRS Ether Products and Services Centre WEB site (http://ether.ipsl.jussieu.fr), where all archived spectroscopic data can be handled through general and user friendly associated management software facilities. More than 350 researchers are

  18. Comet Observations with SIRTF

    NASA Technical Reports Server (NTRS)

    Cruikshank, Dale P.

    2003-01-01

    Comet observations are included in the programs of the Guaranteed Time Observers (GTO) on the Space Infrared Telescope Facility (SIRTF), scheduled to be in space and operational for five years beginning in late 2003. SIRTF is a cryogenic telescope with three basic instruments for imaging, photometry and spectroscopy from 3.6 m to 160 m. All of these capabilities will be used in studies of comets. The intent is to study the infrared radiation (emission) from comets (and dust tails, where relevant) in all stages of evolution, starting with Kuiper Belt objects and Centaurs (thermal emission at 24,70, and 160 m to derive dimensions and albedos). Active comets will be observed spectroscopically and in deep thermal images. Several known or suspected extinct comets will be observed spectroscopically (5-37 m) for information on their surface compositions. There are opportunities for Guest Observers (GO) to propose additional comet work. .

  19. Neutron-Proton Asymmetry Dependence of Spectroscopic Factors in Ar Isotopes

    SciTech Connect

    Lee, Jenny; Tsang, Betty; Shapira, Dan

    2010-01-01

    Spectroscopic factors have been extracted for proton-rich 34Ar and neutron-rich 46Ar using the (p, d) neutron transfer reaction. The experimental results show little reduction of the ground state neutron spectroscopic factor of the proton-rich nucleus 34Ar compared to that of 46Ar. The results suggest that correlations, which generally reduce such spectroscopic factors, do not depend strongly on the neutron-proton asymmetry of the nucleus in this isotopic region as was reported in knockout reactions. The present results are consistent with results from systematic studies of transfer reactions but inconsistent with the trends observed in knockout reaction measurements.

  20. Spectroscopic Engineering in the Submillimeter

    NASA Astrophysics Data System (ADS)

    De Lucia, Frank C.

    2013-06-01

    The field of high-resolution spectroscopy, as represented by the community that supports this meeting, has continued to grow and prosper, in no small part because the field has continued to evolve. Much of this evolution could fall under the rubric, Spectroscopic Engineering. This is especially true in the submillimeter where spectroscopists have taken on much broader roles in fields that have grown out of submillimeter spectroscopy. With specific examples from spectroscopic remote and point sensing, astronomy and atmospheric science, imaging, and process control, opportunities and paths forward for will be considered. Emphasis will be placed on the underlying physics that drives the optimization of applications. Since this is Columbus, at least one complex Hamiltonian will be shown. We will also discuss: What are the opportunities for young people entering the field and how might they be optimized? Is spectroscopy as a tool, less noble than spectroscopy as a science? Is what we do really physics (or even chemistry)? Where does what we do fit into the structure of academia, government, and industry?

  1. Spectroscopic imaging in electron microscopy

    SciTech Connect

    Pennycook, Stephen J; Colliex, C.

    2012-01-01

    In the scanning transmission electron microscope, multiple signals can be simultaneously collected, including the transmitted and scattered electron signals (bright field and annular dark field or Z-contrast images), along with spectroscopic signals such as inelastically scattered electrons and emitted photons. In the last few years, the successful development of aberration correctors for the electron microscope has transformed the field of electron microscopy, opening up new possibilities for correlating structure to functionality. Aberration correction not only allows for enhanced structural resolution with incident probes into the sub-angstrom range, but can also provide greater probe currents to facilitate mapping of intrinsically weak spectroscopic signals at the nanoscale or even the atomic level. In this issue of MRS Bulletin, we illustrate the power of the new generation of electron microscopes with a combination of imaging and spectroscopy. We show the mapping of elemental distributions at atomic resolution and also the mapping of electronic and optical properties at unprecedented spatial resolution, with applications ranging from graphene to plasmonic nanostructures, and oxide interfaces to biology.

  2. A photometrically and spectroscopically confirmed population of passive spiral galaxies

    NASA Astrophysics Data System (ADS)

    Fraser-McKelvie, Amelia; Brown, Michael J. I.; Pimbblet, Kevin A.; Dolley, Tim; Crossett, Jacob P.; Bonne, Nicolas J.

    2016-10-01

    We have identified a population of passive spiral galaxies from photometry and integral field spectroscopy. We selected z < 0.035 spiral galaxies that have WISE colours consistent with little mid-infrared emission from warm dust. Matched aperture photometry of 51 spiral galaxies in ultraviolet, optical and mid-infrared show these galaxies have colours consistent with passive galaxies. Six galaxies form a spectroscopic pilot study and were observed using the Wide-Field Spectrograph to check for signs of nebular emission from star formation. We see no evidence of substantial nebular emission found in previous red spiral samples. These six galaxies possess absorption-line spectra with 4000 Å breaks consistent with an average luminosity-weighted age of 2.3 Gyr. Our photometric and integral field spectroscopic observations confirm the existence of a population of local passive spiral galaxies, implying that transformation into early-type morphologies is not required for the quenching of star formation.

  3. The magnetic field of the hot spectroscopic binary HD 5550

    NASA Astrophysics Data System (ADS)

    Neiner, C.; Alecian, E.

    2015-12-01

    HD 5550 is a spectroscopic binary composed of two A stars observed with Narval at TBL in the frame of the BinaMIcS (Binarity and Magnetic Interactions in various classes of Stars) Large Program. One component of the system is found to be an Ap star with a surprisingly weak dipolar field of ˜65 G. The companion is an Am star for which no magnetic field is detected, with a detection threshold on the dipolar field of ˜40 G. The system is tidally locked, the primary component is synchronised with the orbit, but the system is probably not completely circularised yet. This work is only the second detailed study of magnetic fields in a hot short-period spectroscopic binary. More systems are currently being observed with both Narval at TBL and ESPaDOnS at CFHT within the BinaMIcS project, with the goal of understanding how magnetism can impact binary evolution and vice versa.

  4. A modified potential for HO2 with spectroscopic accuracy.

    PubMed

    Brandão, João; Rio, Carolina M A; Tennyson, Jonathan

    2009-04-01

    Seven ground state potential energy surfaces for the hydroperoxyl radical are compared. The potentials were determined from either high-quality ab initio calculations, fits to spectroscopic data, or a combination of the two approaches. Vibration-rotation calculations are performed on each potential and the results compared with experiment. None of the available potentials is entirely satisfactory although the best spectroscopic results are obtained using the Morse oscillator rigid bender internal dynamics potential [Bunker et al., J. Mol. Spectrosc. 155, 44 (1992)]. We present modifications of the double many-body expansion IV potential of Pastrana et al. [J. Chem. Phys. 94, 8093 (1990)]. These new potentials reproduce the observed vibrational levels and observed vibrational levels and rotational constants, respectively, while preserving the good global properties of the original potential. PMID:19355734

  5. A modified potential for HO2 with spectroscopic accuracy

    NASA Astrophysics Data System (ADS)

    Brandão, João; Rio, Carolina M. A.; Tennyson, Jonathan

    2009-04-01

    Seven ground state potential energy surfaces for the hydroperoxyl radical are compared. The potentials were determined from either high-quality ab initio calculations, fits to spectroscopic data, or a combination of the two approaches. Vibration-rotation calculations are performed on each potential and the results compared with experiment. None of the available potentials is entirely satisfactory although the best spectroscopic results are obtained using the Morse oscillator rigid bender internal dynamics potential [Bunker et al., J. Mol. Spectrosc. 155, 44 (1992)]. We present modifications of the double many-body expansion IV potential of Pastrana et al. [J. Chem. Phys. 94, 8093 (1990)]. These new potentials reproduce the observed vibrational levels and observed vibrational levels and rotational constants, respectively, while preserving the good global properties of the original potential.

  6. Kinetics and spectroscopic observations of atrazine dealkylation on manganese oxides

    SciTech Connect

    Malengreau, N.; Sposito, G.; Cheney, M.A.; Crowley, D.E.

    1997-12-31

    Abiotic transformations of organic pollutants are often neglected in remediation scenarios but nonetheless can contribute significantly to detoxification. Mn oxide minerals are capable of degrading organic pollutants adsorbed to their surfaces by both redox and proton-promoted mechanisms. Concurrently with calorimetric, gas-pressure, chromatographic, and ESR methods, we used ICP, DRS, DRIFT, and FTIR spectroscopies to investigate atrazine degradation on three Mn oxides. We found that N-dealkylation can occur abiotically, leading to the formation of deethylatrazine and deisopropylatrazine. The Mn extractability after degradation of atrazine was highly dependent on the Mn oxide. Extractable Mn increased with time for cryptomelane, was constant for pyrolusite, and remained very low for birnessite. The extractable Mn is Mn(II). UV signatures of atrazine by-products were different from one another and were used to trace degradation products at the Mn oxide surface. Mechanistic interpretation of the in situ reaction kinetics and thermodynamics will be discussed.

  7. Balloon-borne spectroscopic observation of the infrared hydroxyl airglow.

    PubMed

    Lowe, R P; Lytle, E A

    1973-03-01

    A balloon-borne grating spectrometer has been used to study the spectrum of the airglow between 1.8 microm and 3.6 microm and its diurnal variation. The principal features identified are the bands of the Deltaupsilon = 2 and Deltaupsilon = 1 sequences of the vibration-rotation spectrum of OH. The brightness of the 1-0 band at night was measured to be in the range 270-400 kR on two flights. A sudden decrease in the intensity of the hydroxyl bands occurred in morning twilight at a solar depression of 4 degrees and is ascribed to the photodissociation of ozone. The temperature, as indicated by the Q/R branch ratio, rose from 170 K at night to 255 K at noon indicating a reduction in the height of the emitting layer during the day.

  8. Multi-site campaign for transit timing variations of WASP-12 b: possible detection of a long-period signal of planetary origin

    NASA Astrophysics Data System (ADS)

    Maciejewski, G.; Dimitrov, D.; Seeliger, M.; Raetz, St.; Bukowiecki, Ł.; Kitze, M.; Errmann, R.; Nowak, G.; Niedzielski, A.; Popov, V.; Marka, C.; Goździewski, K.; Neuhäuser, R.; Ohlert, J.; Hinse, T. C.; Lee, J. W.; Lee, C.-U.; Yoon, J.-N.; Berndt, A.; Gilbert, H.; Ginski, Ch.; Hohle, M. M.; Mugrauer, M.; Röll, T.; Schmidt, T. O. B.; Tetzlaff, N.; Mancini, L.; Southworth, J.; Dall'Ora, M.; Ciceri, S.; Zambelli, R.; Corfini, G.; Takahashi, H.; Tachihara, K.; Benkő, J. M.; Sárneczky, K.; Szabo, Gy. M.; Varga, T. N.; Vaňko, M.; Joshi, Y. C.; Chen, W. P.

    2013-03-01

    Aims: The transiting planet WASP-12 b was identified as a potential target for transit-timing studies because a departure from a linear ephemeris has been reported in the literature. Such deviations could be caused by an additional planet in the system. We attempt to confirm the claimed variations in transit timing and interpret their origin. Methods: We organised a multi-site campaign to observe transits by WASP-12 b in three observing seasons, using 0.5-2.6-metre telescopes. Results: We obtained 61 transit light curves, many of them with sub-millimagnitude precision. The simultaneous analysis of the best-quality datasets allowed us to obtain refined system parameters, which agree with values reported in previous studies. The residuals versus a linear ephemeris reveal a possible periodic signal that may be approximated by a sinusoid with an amplitude of 0.00068 ± 0.00013 d and period of 500 ± 20 orbital periods of WASP-12 b. The joint analysis of timing data and published radial velocity measurements results in a two-planet model that explains observations better than do single-planet scenarios. We hypothesise that WASP-12 b might not be the only planet in the system, and there might be the additional 0.1 MJup body on a 3.6-d eccentric orbit. A dynamical analysis indicates that the proposed two-planet system is stable on long timescales. Partly based on (1) data collected with the Nordic Optical Telescope, operated on the island of La Palma jointly by Denmark, Finland, Iceland, Norway, and Sweden, in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias, (2) observations made at the Centro Astronómico Hispano Alemán (CAHA), operated jointly by the Max-Planck Institut für Astronomie and the Instituto de Astrofísica de Andalucía (CSIC), (3) data collected with telescopes at the Rozhen National Astronomical Observatory, and (4) observations obtained with telescopes of the University Observatory Jena, which is operated

  9. Spectroscopic ellipsometry study of novel nanostructured transparent conducting oxide structures

    NASA Astrophysics Data System (ADS)

    Khosroabadi, Akram A.; Norwood, R. A.

    2013-02-01

    Spectroscopic ellipsometry has been used to find the optical constants, including refractive index, extinction coefficient, thickness and volume fraction of nanostructured transparent conducting oxides including indium tin oxide (ITO) and indium zinc oxide (IZO). We observed sharp features in the ellipsometry data, with the spectral peaks and positions depending on the nanostructure dimensions and material. A superposition of Lorentzian oscillators and the effective medium approximation has been applied to determine the volume ratio of voids and nanopillars, thereby providing the effective optical constants.

  10. Highlights of the Brazilian Solar Spectroscope (bss)

    NASA Astrophysics Data System (ADS)

    Sawant, Hanumant; Cecatto, José; Meszarosova, Hana; Faria, Claudio; Fernandes, Francisco; Karlicky, Marian; Andrade, Maria

    The digital, decimetric (1000-2500 MHz) Brazilian Solar Spectroscope (BSS) with high time (10- 1000 ms) and frequency (1-10 MHz) resolution is in regular operation since April, 1998, at the National Space Research Institute (INPE) at Sao Jose dos Campos, Brazil. The BSS has now been upgraded with a new digital data acquisition and data processing system. The new version of the BSS has a 14 bit A/D unit which permits improved combination of the observational parameters with a capability to record up to 200 frequency channels available in a selectable frequency range of 1000-2500 MHz. It permits data acquisition up to 5 ms time resolution with a limited number of frequency channels. The software system of the BSS is composed by two distinct modules: The first, data acquisition system provides a flexible Graphical User Interface (GUI) that allows one to choose a number of observational parameters. The second module is the real time visualization system that permits real time visualization of the observed dynamic spectrum and additionally has procedures for visualization and preliminary analysis of the recorded solar spectra. Using the new visualization system, we have realized two new types of dm-radio fine structures: narrow band type III bursts with positive/negative group frequency drift and dots-emissions arranged in zebras and fibers.

  11. Development of a Multi-Site and Multi-Device Webgis-Based Tool for Tidal Current Energy Development

    NASA Astrophysics Data System (ADS)

    Ang, M. R. C. O.; Panganiban, I. K.; Mamador, C. C.; De Luna, O. D. G.; Bausas, M. D.; Cruz, J. P.

    2016-06-01

    A multi-site, multi-device and multi-criteria decision support tool designed to support the development of tidal current energy in the Philippines was developed. Its platform is based on Geographic Information Systems (GIS) which allows for the collection, storage, processing, analyses and display of geospatial data. Combining GIS tools with open source web development applications, it becomes a webGIS-based marine spatial planning tool. To date, the webGIS-based tool displays output maps and graphs of power and energy density, site suitability and site-device analysis. It enables stakeholders and the public easy access to the results of tidal current energy resource assessments and site suitability analyses. Results of the initial development showed that it is a promising decision support tool for ocean renewable energy project developments.

  12. Completion Report for Multi-Site Incentive MRT 2779 Implement ASC Tripod Initiative by 30SEP08

    SciTech Connect

    East, D; Cerutti, J; Noe, J; Cupps, K; Loncaric, J; Sturtevant, J

    2008-09-22

    This report provides documentation and evidence for the completion of the deployment of the Tripod common operating system (TripodOS, also known as and generally referred to below as TOSS). Background documents for TOSS are provided in Appendices A and B, including the initial TOSS proposal accepted by ASC HQ and Executives in July 2007 and a Governance Model defined by a Tri-Lab working group in September 2007. Appendix C contains a document that clarifies the intent and requirements for the completion criteria associated with MRT 2779. The deployment of TOSS is a Multi-Site Incentive from the ASC FY08-09 Implementation Plan due at the end of Quarter 4 in FY08.

  13. Social-cognitive theory mediators of behavior change in the National Institute of Mental Health Multisite HIV Prevention Trial.

    PubMed

    2001-09-01

    The National Institute of Mental Health Multisite HIV Prevention Trial was a trial of an intervention to reduce sexual HIV risk behaviors among 3,706 low-income at-risk men and women at 7 U.S. research sites. The intervention, based on social-cognitive theory and designed to influence behavior change by improving expected outcomes of condom use and increasing knowledge, skills, and self-efficacy to execute safer sex behaviors, was effective relative to a control condition in reducing sexual risk behavior. At 3 months after completion of the intervention, measures of these potential mediators were higher in the intervention than in the control condition. Although the effect of the intervention on sexual risk behavior was significantly reduced when the variables were controlled statistically, supporting the hypothesis of their mediation of the intervention effect, most of the effect remained unexplained, indicating the influence of unmeasured factors on outcome.

  14. A MultiSite Gateway Toolkit for Rapid Cloning of Vertebrate Expression Constructs with Diverse Research Applications

    PubMed Central

    Fowler, Daniel K.; Stewart, Scott; Seredick, Steve; Eisen, Judith S.

    2016-01-01

    Recombination-based cloning is a quick and efficient way to generate expression vectors. Recent advancements have provided powerful recombinant DNA methods for molecular manipulations. Here, we describe a novel collection of three-fragment MultiSite Gateway cloning system-compatible vectors providing expanded molecular tools for vertebrate research. The components of this toolkit encompass a broad range of uses such as fluorescent imaging, dual gene expression, RNA interference, tandem affinity purification, chemically-inducible dimerization and lentiviral production. We demonstrate examples highlighting the utility of this toolkit for producing multi-component vertebrate expression vectors with diverse primary research applications. The vectors presented here are compatible with other Gateway toolkits and collections, facilitating the rapid generation of a broad range of innovative DNA constructs for biological research. PMID:27500400

  15. Development and implementation of a quality assurance infrastructure in a multisite home visitation program in Ohio and Kentucky.

    PubMed

    Ammerman, Robert T; Putnam, Frank W; Kopke, Jonathan E; Gannon, Thomas A; Short, Jodie A; Van Ginkel, Judith B; Clark, Margaret J; Carrozza, Mark A; Spector, Alan R

    2007-01-01

    As home visitation programs go to scale, numerous challenges are faced in implementation and quality assurance. This article describes the origins and implementation of Every Child Succeeds, a multisite home visitation program in southwestern Ohio and Northern Kentucky. In order to optimize quality assurance and generate new learning for the field, a Web-based system (eECS) was designed to systematically collect and use data. Continuous quality assurance procedures derived from business and industry have been established. Findings from data collection have documented outcomes, and have identified clinical needs that potentially undermine the impact of home visitation. An augmented module approach has been used to address these needs, and a program to treat maternal depression is described as an example of this approach. Challenges encountered are also discussed.

  16. Spectroscopic Needs for Imaging Dark Energy Experiments

    SciTech Connect

    Newman, Jeffrey A.; Slosar, Anze; Abate, Alexandra; Abdalla, Filipe B.; Allam, Sahar; Allen, Steven W.; Ansari, Reza; Bailey, Stephen; Barkhouse, Wayne A.; Beers, Timothy C.; Blanton, Michael R.; Brodwin, Mark; Brownstein, Joel R.; Brunner, Robert J.; Carrasco-Kind, Matias; Cervantes-Cota, Jorge; Chisari, Nora Elisa; Colless, Matthew; Comparat, Johan; Coupon, Jean; Cheu, Elliott; Cunha, Carlos E.; de la Macorra, Alex; Dell’Antonio, Ian P.; Frye, Brenda L.; Gawiser, Eric J.; Gehrels, Neil; Grady, Kevin; Hagen, Alex; Hall, Patrick B.; Hearin, Andrew P.; Hildebrandt, Hendrik; Hirata, Christopher M.; Ho, Shirley; Honscheid, Klaus; Huterer, Dragan; Ivezic, Zeljko; Kneib, Jean -Paul; Kruk, Jeffrey W.; Lahav, Ofer; Mandelbaum, Rachel; Marshall, Jennifer L.; Matthews, Daniel J.; Menard, Brice; Miquel, Ramon; Moniez, Marc; Moos, H. W.; Moustakas, John; Papovich, Casey; Peacock, John A.; Park, Changbom; Rhodes, Jason; Sadeh, Iftach; Schmidt, Samuel J.; Stern, Daniel K.; Tyson, J. Anthony; von der Linden, Anja; Wechsler, Risa H.; Wood-Vasey, W. M.; Zentner, A.

    2015-03-15

    Ongoing and near-future imaging-based dark energy experiments are critically dependent upon photometric redshifts (a.k.a. photo-z’s): i.e., estimates of the redshifts of objects based only on flux information obtained through broad filters. Higher-quality, lower-scatter photo-z’s will result in smaller random errors on cosmological parameters; while systematic errors in photometric redshift estimates, if not constrained, may dominate all other uncertainties from these experiments. The desired optimization and calibration is dependent upon spectroscopic measurements for secure redshift information; this is the key application of galaxy spectroscopy for imaging-based dark energy experiments. Hence, to achieve their full potential, imaging-based experiments will require large sets of objects with spectroscopically-determined redshifts, for two purposes: Training: Objects with known redshift are needed to map out the relationship between object color and z (or, equivalently, to determine empirically-calibrated templates describing the rest-frame spectra of the full range of galaxies, which may be used to predict the color-z relation). The ultimate goal of training is to minimize each moment of the distribution of differences between photometric redshift estimates and the true redshifts of objects, making the relationship between them as tight as possible. The larger and more complete our “training set” of spectroscopic redshifts is, the smaller the RMS photo-z errors should be, increasing the constraining power of imaging experiments; Requirements: Spectroscopic redshift measurements for ~30,000 objects over >~15 widely-separated regions, each at least ~20 arcmin in diameter, and reaching the faintest objects used in a given experiment, will likely be necessary if photometric redshifts are to be trained and calibrated with conventional techniques. Larger, more complete samples (i.e., with longer exposure times) can improve photo-z algorithms and reduce scatter

  17. Spectroscopic Needs for Imaging Dark Energy Experiments

    DOE PAGES

    Newman, Jeffrey A.; Slosar, Anze; Abate, Alexandra; Abdalla, Filipe B.; Allam, Sahar; Allen, Steven W.; Ansari, Reza; Bailey, Stephen; Barkhouse, Wayne A.; Beers, Timothy C.; et al

    2015-03-15

    Ongoing and near-future imaging-based dark energy experiments are critically dependent upon photometric redshifts (a.k.a. photo-z’s): i.e., estimates of the redshifts of objects based only on flux information obtained through broad filters. Higher-quality, lower-scatter photo-z’s will result in smaller random errors on cosmological parameters; while systematic errors in photometric redshift estimates, if not constrained, may dominate all other uncertainties from these experiments. The desired optimization and calibration is dependent upon spectroscopic measurements for secure redshift information; this is the key application of galaxy spectroscopy for imaging-based dark energy experiments. Hence, to achieve their full potential, imaging-based experiments will require large setsmore » of objects with spectroscopically-determined redshifts, for two purposes: Training: Objects with known redshift are needed to map out the relationship between object color and z (or, equivalently, to determine empirically-calibrated templates describing the rest-frame spectra of the full range of galaxies, which may be used to predict the color-z relation). The ultimate goal of training is to minimize each moment of the distribution of differences between photometric redshift estimates and the true redshifts of objects, making the relationship between them as tight as possible. The larger and more complete our “training set” of spectroscopic redshifts is, the smaller the RMS photo-z errors should be, increasing the constraining power of imaging experiments; Requirements: Spectroscopic redshift measurements for ~30,000 objects over >~15 widely-separated regions, each at least ~20 arcmin in diameter, and reaching the faintest objects used in a given experiment, will likely be necessary if photometric redshifts are to be trained and calibrated with conventional techniques. Larger, more complete samples (i.e., with longer exposure times) can improve photo-z algorithms and reduce

  18. The Hubble Spectroscopic Legacy Archive

    NASA Astrophysics Data System (ADS)

    Peeples, Molly S.; Tumlinson, Jason; Fox, Andrew; Aloisi, Alessandra; Ayres, Thomas R.; Danforth, Charles; Fleming, Scott W.; Jenkins, Edward B.; Jedrzejewski, Robert I.; Keeney, Brian A.; Oliveira, Cristina M.

    2016-01-01

    With no future space ultraviolet instruments currently planned, the data from the UV spectrographs aboard the Hubble Space Telescope have a legacy value beyond their initial science goals. The Hubble Spectroscopic Legacy Archive will provide to the community new science-grade combined spectra for all publicly available data obtained by the Cosmic Origins Spectrograph (COS) and the Space Telescope Imaging Spectrograph (STIS). These data will be packaged into "smart archives" according to target type and scientific themes to facilitate the construction of archival samples for common science uses. A new "quick look" capability will make the data easy for users to quickly access, assess the quality of, and download for archival science starting in Cycle 24, with the first generation of these products for the FUV modes of COS available online via MAST in early 2016.

  19. Spectroscopic Subsystems in Nearby Wide Binaries

    NASA Astrophysics Data System (ADS)

    Tokovinin, Andrei

    2015-12-01

    Radial velocity (RV) monitoring of solar-type visual binaries has been conducted at the CTIO/SMARTS 1.5 m telescope to study short-period systems. The data reduction is described, and mean and individual RVs of 163 observed objects are given. New spectroscopic binaries are discovered or suspected in 17 objects, and for some of them the orbital periods could be determined. Subsystems are efficiently detected even in a single observation by double lines and/or by the RV difference between the components of visual binaries. The potential of this detection technique is quantified by simulation and used for statistical assessment of 96 wide binaries within 67 pc. It is found that 43 binaries contain at least one subsystem, and the occurrence of subsystems is equally probable in either primary or secondary components. The frequency of subsystems and their periods matches the simple prescription proposed by the author. The remaining 53 simple wide binaries with a median projected separation of 1300 AU have an RV difference distribution between their components that is not compatible with the thermal eccentricity distribution f (e) = 2e but rather matches the uniform eccentricity distribution.

  20. SPECTROSCOPIC SUBSYSTEMS IN NEARBY WIDE BINARIES

    SciTech Connect

    Tokovinin, Andrei

    2015-12-15

    Radial velocity (RV) monitoring of solar-type visual binaries has been conducted at the CTIO/SMARTS 1.5 m telescope to study short-period systems. The data reduction is described, and mean and individual RVs of 163 observed objects are given. New spectroscopic binaries are discovered or suspected in 17 objects, and for some of them the orbital periods could be determined. Subsystems are efficiently detected even in a single observation by double lines and/or by the RV difference between the components of visual binaries. The potential of this detection technique is quantified by simulation and used for statistical assessment of 96 wide binaries within 67 pc. It is found that 43 binaries contain at least one subsystem, and the occurrence of subsystems is equally probable in either primary or secondary components. The frequency of subsystems and their periods matches the simple prescription proposed by the author. The remaining 53 simple wide binaries with a median projected separation of 1300 AU have an RV difference distribution between their components that is not compatible with the thermal eccentricity distribution f (e) = 2e but rather matches the uniform eccentricity distribution.

  1. Rado Köveslighety's spectroscopic work

    NASA Astrophysics Data System (ADS)

    Balázs, Lajos G.; Vargha, Magda; Zsoldos, Endre

    2008-07-01

    Kirchhoff and Bunsen's revolutionary discovery of spectral analysis in 1859 showed that observation of spectra made it possible to study the chemical composition of emitting bodies. Thermodynamics predicted the existence of black body radiation. The first successful spectral equation of black body radiation was the theory of continuous spectra of celestial bodies by Rado von Kövesligethy (published in 1885 in Hungarian, in 1890 in German). Kövesligethy made several assumptions on the matter-radiation interaction. Based on these assumptions, he derived a spectral equation with the following properties: the spectral distribution of radiation depended only on the temperature, the total irradiated energy was finite (fifteen years before Planck!) and the wavelength of the intensity maximum was inversely proportional to the temperature (eight years before Wien!). Using his spectral equation, he estimated the temperature of several celestial bodies, including the Sun. As a byproduct he developed a theory of spectroscopic instruments. He presented a comprehensive discussion on the quantitative relationship between astrophysical spectra and the observer, equipped with some kind of instrument (telescope, spectrograph, detector, etc.). We briefly summarize his main results.

  2. Spectroscopic and Interferometric Measurements of Nine K Giant Stars

    NASA Astrophysics Data System (ADS)

    Baines, Ellyn K.; Döllinger, Michaela P.; Guenther, Eike W.; Hatzes, Artie P.; Hrudkovu, Marie; van Belle, Gerard T.

    2016-09-01

    We present spectroscopic and interferometric measurements for a sample of nine K giant stars. These targets are of particular interest because they are slated for stellar oscillation observations. Our improved parameters will directly translate into reduced errors in the final masses for these stars when interferometric radii and asteroseismic densities are combined. Here, we determine each star’s limb-darkened angular diameter, physical radius, luminosity, bolometric flux, effective temperature, surface gravity, metallicity, and mass. When we compare our interferometric and spectroscopic results, we find no systematic offsets in the diameters and the values generally agree within the errors. Our interferometric temperatures for seven of the nine stars are hotter than those determined from spectroscopy with an average difference of about 380 K.

  3. Silicon immersion gratings and their spectroscopic applications

    NASA Astrophysics Data System (ADS)

    Ge, Jian; Zhao, Bo; Powell, Scott; Fletcher, Adam; Wan, Xiaoke; Chang, Liang; Jakeman, Hali; Koukis, Dimitrios; Tanner, David B.; Ebbets, Dennis; Weinberg, Jonathan; Lipscy, Sarah; Nyquist, Rich; Bally, John

    2012-09-01

    Silicon immersion gratings (SIGs) offer several advantages over the commercial echelle gratings for high resolution infrared (IR) spectroscopy: 3.4 times the gain in dispersion or ~10 times the reduction in the instrument volume, a multiplex gain for a large continuous wavelength coverage and low cost. We present results from lab characterization of a large format SIG of astronomical observation quality. This SIG, with a 54.74 degree blaze angle (R1.4), 16.1 l/mm groove density, and 50x86 mm2 grating area, was developed for high resolution IR spectroscopy (R~70,000) in the near IR (1.1-2.5 μm). Its entrance surface was coated with a single layer of silicon nitride antireflection (AR) coating and its grating surface was coated with a thin layer of gold to increase its throughput at 1.1-2.5 μm. The lab measurements have shown that the SIG delivered a spectral resolution of R=114,000 at 1.55 μm with a lab testing spectrograph with a 20 mm diameter pupil. The measured peak grating efficiency is 72% at 1.55 μm, which is consistent with the measurements in the optical wavelengths from the grating surface at the air side. This SIG is being implemented in a new generation cryogenic IR spectrograph, called the Florida IR Silicon immersion grating spectrometer (FIRST), to offer broad-band high resolution IR spectroscopy with R=72,000 at 1.4-1.8 um under a typical seeing condition in a single exposure with a 2kx2k H2RG IR array at the robotically controlled Tennessee State University 2-meter Automatic Spectroscopic Telescope (AST) at Fairborn Observatory in Arizona. FIRST is designed to provide high precision Doppler measurements (~4 m/s) for the identification and characterization of extrasolar planets, especially rocky planets in habitable zones, orbiting low mass M dwarf stars. It will also be used for other high resolution IR spectroscopic observations of such as young stars, brown dwarfs, magnetic fields, star formation and interstellar mediums. An optimally designed

  4. An empirical evaluation of three vibrational spectroscopic methods for detection of aflatoxins in maize.

    PubMed

    Lee, Kyung-Min; Davis, Jessica; Herrman, Timothy J; Murray, Seth C; Deng, Youjun

    2015-04-15

    Three commercially available vibrational spectroscopic techniques, including Raman, Fourier transform near infrared reflectance (FT-NIR), and Fourier transform infrared (FTIR) were evaluated to help users determine the spectroscopic method best suitable for aflatoxin analysis in maize (Zea mays L.) grain based on their relative efficiency and predictive ability. Spectral differences of Raman and FTIR spectra were more marked and pronounced among aflatoxin contamination groups than those of FT-NIR spectra. From the observations and findings in our current and previous studies, Raman and FTIR spectroscopic methods are superior to FT-NIR method in terms of predictive power and model performance for aflatoxin analysis and they are equally effective and accurate in predicting aflatoxin concentration in maize. The present study is considered as the first attempt to assess how spectroscopic techniques with different physical processes can influence and improve accuracy and reliability for rapid screening of aflatoxin contaminated maize samples.

  5. Streamlining IRB review in multisite trials through single-study IRB Cooperative Agreements: experience of the Beta-Carotene and Retinol Efficacy Trial (CARET).

    PubMed

    Thornquist, Mark D; Edelstein, Cim; Goodman, Gary E; Omenn, Gilbert S

    2002-02-01

    With their extensive data and specimen repositories, clinical trials are a long-term, valuable resource to health researchers. However, assuring protection of participants' rights can be challenging, particularly when such trials are conducted at multiple sites with multiple Institutional Review Boards (IRBs). One little-used mechanism that can streamline IRB review in multisite trials while maintaining participants' protections is the single-study IRB Cooperative Agreement. This agreement is entirely different from reciprocity agreements between institutions. Beginning in 1996, the Beta-Carotene and Retinol Efficacy Trial established single-study IRB Cooperative Agreements among its performance sites, which reduced the average time to complete IRB approval from over 6 months to 1 month for each of many substudies. We describe our experience and make recommendations for other multisite clinical trials.

  6. Spectroscopic study of the extremely fast rotating star 44 Geminorum

    NASA Astrophysics Data System (ADS)

    Iliev, L.; Vennes, S.; Kawka, A.; Kubat, J.; Nemeth, P.; Borisov, G.; KRaus, M.

    Stars with extremely fast rotation represent interesting challenge to modern understanding of the stellar evolution. The reasons why such a spin-up process should occur during the evolution to otherwise normal star are still not well understood. Already in the beginning of the XX century Otto Struve proposed that fast rotation of the group of stars spectroscopically classified as Be could be the main reason for the formation of observed disks of circumstellar material around them. This circumstellar material is responsible for the emission lines observed in the spectrum of Be-stars as well as for the whole complex of spectral and photometrical patterns called in general Be-phenomenon.

  7. Distributed hydrological modeling in a large-scale watershed of Northern China: multi-site model calibration, validation, and sensitivity analysis

    NASA Astrophysics Data System (ADS)

    Wang, S.; Zhang, Z.; Sun, G.; Strauss, P.; Guo, J.; Tang, Y.

    2012-05-01

    Model calibration is a complex task for large watersheds, especially for those in a heterogeneous mountain environment where multi-objective calibration strategy is essential. That may improve a model's capability to capture the spatial variations of the internal hydrologic variables. This study used the physically-based distributed hydrologic model, MIKESHE, to contrast a lumped calibration protocol that uses data measured at one single outlet to a multi-site calibration method which employed streamflow measurements at three separate stations within the large Chaohe River basin in Northern China. The results showed that, the single-site calibrated model was able to sufficiently simulate the hydrographs for two of the three stations (Nash-sutchliffe coefficient of 0.65-0.75, and correlation coefficient 0.81-0.87 during the testing period), but model performance was poor at the third station (EF only 0.44). By using the multi-site measurements model calibration reached a compromise between the different stations, the model reasonably representing the hydrographs of all three stations with EF ranging from 0.59-0.72. The modeling calibration results suggested that the dominant hydrological processes varied across the large watershed with upstream area dominated by slow groundwater and middle- and down-stream areas dominated by relatively quick interflow. We conclude that to account for the different hydrological process of watershed with large heterogeneity, it is necessary to employ a multi-site calibration protocol to reduce prediction errors.

  8. Automated pipelines for spectroscopic analysis

    NASA Astrophysics Data System (ADS)

    Allende Prieto, C.

    2016-09-01

    The Gaia mission will have a profound impact on our understanding of the structure and dynamics of the Milky Way. Gaia is providing an exhaustive census of stellar parallaxes, proper motions, positions, colors and radial velocities, but also leaves some glaring holes in an otherwise complete data set. The radial velocities measured with the on-board high-resolution spectrograph will only reach some 10 % of the full sample of stars with astrometry and photometry from the mission, and detailed chemical information will be obtained for less than 1 %. Teams all over the world are organizing large-scale projects to provide complementary radial velocities and chemistry, since this can now be done very efficiently from the ground thanks to large and mid-size telescopes with a wide field-of-view and multi-object spectrographs. As a result, automated data processing is taking an ever increasing relevance, and the concept is applying to many more areas, from targeting to analysis. In this paper, I provide a quick overview of recent, ongoing, and upcoming spectroscopic surveys, and the strategies adopted in their automated analysis pipelines.

  9. SDSS spectroscopic survey of stars

    SciTech Connect

    Ivezic, Zeljko; Schlegel, D.; Uomoto, A.; Bond, N.; Beers, T.; Allende Prieto, C.; Wilhelm, R.; Lee, Y.Sun; Sivarani, T.; Juric, M.; Lupton, R.; /Washington U., Seattle, Astron. Dept. /LBL, Berkeley /Johns Hopkins U. /Princeton U. /Michigan State U. /Texas U. /Texas Tech. /UC, Santa Cruz /Fermilab /Naval Observ., Flagstaff /Drexel U.

    2007-01-01

    In addition to optical photometry of unprecedented quality, the Sloan Digital Sky Survey (SDSS) is also producing a massive spectroscopic database. They discuss determination of stellar parameters, such as effective temperature, gravity and metallicity from SDSS spectra, describe correlations between kinematics and metallicity, and study their variation as a function of the position in the Galaxy. They show that stellar parameter estimates by Beers et al. show a good correlation with the position of a star in the g-r vs. u-g color-color diagram, thereby demonstrating their robustness as well as a potential for photometric parameter estimation methods. Using Beers et al. parameters, they find that the metallicity distribution of the Milky Way stars at a few kpc from the galactic plane is bimodal with a local minimum at [Z/Z{sub {circle_dot}}] {approx} -1.3. The median metallicity for the low-metallicity [Z/Z{sub {circle_dot}}] < =1.3 subsample is nearly independent of Galactic cylindrical coordinates R and z, while it decreases with z for the high-metallicity [Z/Z{sub {circle_dot}}] > -1.3 sample. they also find that the low-metallicity sample has {approx} 2.5 times larger velocity dispersion and that it does not rotate (at the {approx} 10 km/s level), while the rotational velocity of the high-metallicity sample decreases smoothly with the height above the galactic plane.

  10. Vibrational spectroscopic characterization of fluoroquinolones

    NASA Astrophysics Data System (ADS)

    Neugebauer, U.; Szeghalmi, A.; Schmitt, M.; Kiefer, W.; Popp, J.; Holzgrabe, U.

    2005-05-01

    Quinolones are important gyrase inhibitors. Even though they are used as active agents in many antibiotics, the detailed mechanism of action on a molecular level is so far not known. It is of greatest interest to shed light on this drug-target interaction to provide useful information in the fight against growing resistances and obtain new insights for the development of new powerful drugs. To reach this goal, on a first step it is essential to understand the structural characteristics of the drugs and the effects that are caused by the environment in detail. In this work we report on Raman spectroscopical investigations of a variety of gyrase inhibitors (nalidixic acid, oxolinic acid, cinoxacin, flumequine, norfloxacin, ciprofloxacin, lomefloxacin, ofloxacin, enoxacin, sarafloxacin and moxifloxacin) by means of micro-Raman spectroscopy excited with various excitation wavelengths, both in the off-resonance region (532, 633, 830 and 1064 nm) and in the resonance region (resonance Raman spectroscopy at 244, 257 and 275 nm). Furthermore DFT calculations were performed to assign the vibrational modes, as well as for an identification of intramolecular hydrogen bonding motifs. The effect of small changes in the drug environment was studied by adding successively small amounts of water until physiological low concentrations of the drugs in aqueous solution were obtained. At these low concentrations resonance Raman spectroscopy proved to be a useful and sensitive technique. Supplementary information was obtained from IR and UV/vis spectroscopy.

  11. The X-type asteroids: spectroscopic results

    NASA Astrophysics Data System (ADS)

    Fornasier, S.; Clark, B. E.; Dotto, E.

    2011-10-01

    We have carried out a spectroscopic survey in the 2004-2007 years of X-type asteroids in the visible and near infrared range at the NTT, TNG and IRTF telescopes. In this paper we present new VIS-NIR spectra of 24 asteroids belonging to the X type as defined by Tholen & Barucci [1], that is an "E-M-P" type asteroid for which albedo information was not available at the time of their classification. We find a large variety of near-infrared spectral behaviors within the X class, and we identify weak absorption bands in spectra of 11 asteroids. Our spectra, together with the new albedo values [2], can be used to suggest new Tholen classifications for these objects. To constrain their compositions, we conduct a search for meteorite analogues using the RELAB database, and we model the asteroid surface composition with geographical mixtures of selected minerals when a meteorite match is not satisfactory. In addition, we present an analysis of X complex spectral slope values and class distributions in the asteroid main belt, where we include previously published observations ofMand E-type asteroids obtained during the same survey [3,4].

  12. Spectroscopic characterization of inductive binding in ions

    NASA Astrophysics Data System (ADS)

    Lessen, D.; Asher, R. L.; Brucat, P. J.

    1990-12-01

    Molecular ions without conventional covalent bonds have been synthesized via supersonic adiabatic expansion and studied in a tandem time-of-fligth mass spectrometer. Resonant laser photofragmentation of these ions reveal a wealth of vibrational and electronic structure previously unknown. The ground and excited state "bond" strengths of transition-metal rare-gas diatomic ions (MRg+) are determined spectroscopically. The vibrational structure of these diatomics has been analyzed using model metal rare-gas interatomic potential that incorporates only charge induced-dipole as the attractive force. This potential is used to predict the binding energy and structure of the MRg+n, n = 2-14, clusters. V+ is predicted to be four coordinate in its first "solvation shell" with Ar in accord with experimental observation. The dynamic of the MRg+n ions is probed by classical trajectory analysis of a model many-body potential. An example demonstrates that the lowest energy structure of a cluster can be less important to its dynamical structure at finite temperature than higher-lying, lower-symmetry isomers. Resonant photodissociation spectroscopy is used to show the existence of the charge dipole bound V(OH2)+ in both ground and excited states.

  13. IMPROVED SPECTROSCOPIC PARAMETERS FOR TRANSITING PLANET HOSTS

    SciTech Connect

    Torres, Guillermo; Holman, Matthew J.; Carter, Joshua A.; Fischer, Debra A.; Sozzetti, Alessandro; Buchhave, Lars A.; Winn, Joshua N.

    2012-10-01

    We report homogeneous spectroscopic determinations of the effective temperature, metallicity, and projected rotational velocity for the host stars of 56 transiting planets. Our analysis is based primarily on the stellar parameter classification (SPC) technique. We investigate systematic errors by examining subsets of the data with two other methods that have often been used in previous studies (Spectroscopy Made Easy (SME) and MOOG). The SPC and SME results, both based on comparisons between synthetic spectra and actual spectra, show strong correlations between T{sub eff}, [Fe/H], and log g when solving for all three quantities simultaneously. In contrast the MOOG results, based on a more traditional curve-of-growth approach, show no such correlations. To combat the correlations and improve the accuracy of the temperatures and metallicities, we repeat the SPC analysis with a constraint on log g based on the mean stellar density that can be derived from the analysis of the transit light curves. Previous studies that have not taken advantage of this constraint have been subject to systematic errors in the stellar masses and radii of up to 20% and 10%, respectively, which can be larger than other observational uncertainties, and which also cause systematic errors in the planetary mass and radius.

  14. Asiago spectroscopic classification of SN 2016gdt

    NASA Astrophysics Data System (ADS)

    Ochner, P.; Benetti, S.; Cappellaro, E.; Elias-Rosa, N.; Pastorello, A.; Tomasella, L.; Turatto, M.; Terreran, G.

    2016-09-01

    The Asiago Transient Classification Program (Tomasella et al. 2014, AN, 335, 841) reports the spectroscopic classification of SN2016gdt in IC1407. The target was supplied by the Italian Supernovae Search Project (ISSP).

  15. MAMA Spectroscopic Sensitivity and Focus Monitor

    NASA Astrophysics Data System (ADS)

    Lennon, Daniel

    2009-07-01

    Monitor sensitivity of each MAMA grating mode to detect any change due tocontamination or other causes. Also monitor the STIS focus in a spectroscopic and animaging mode.Whenever possible, obtain parallel airglow spectra with COS.

  16. Spectroscopic orbits and variations of RS Ophiuchi

    NASA Astrophysics Data System (ADS)

    Brandi, E.; Quiroga, C.; Mikołajewska, J.; Ferrer, O. E.; García, L. G.

    2009-04-01

    Aims: The aims of our study are to improve the orbital elements of the giant and to derive the spectroscopic orbit for the white dwarf companion of the symbiotic system RS Oph. Spectral variations related to the 2006 outburst are also studied. Methods: We performed an analysis of about seventy optical and near infrared spectra of RS Oph that were acquired between 1998 and June 2008. The spectroscopic orbits were obtained by measuring the radial velocities of the cool component absorption lines and the broad Hα emission wings, which seem to be associated with the hot component. A set of cF-type absorption lines were also analyzed for a possible connection with the hot component motion. Results: A new period of 453.6 days and a mass ratio, q = M_g/Mh = 0.59 ± 0.05 were determined. Assuming a massive white dwarf as the hot component (Mh = 1.2-1.4 M⊙) the red giant mass is Mg = 0.68-0.80 M⊙ and the orbit inclination, i = 49°-52°. The cF-type lines are not associated with either binary component, and are most likely formed in the material streaming towards the hot component. We also confirm the presence of the Li I doublet in RS Oph and its radial velocities fit very well to the M-giant radial velocity curve. Regardless of the mechanism involved to produce lithium, its origin is most likely from within the cool giant rather than material captured by the giant at the time of the nova explosion. The quiescent spectra reveal a correlation of the H I and He I emission line fluxes with the monochromatic magnitudes at 4800 Å, indicating that the hot component activity is responsible for those flux variations. We also discuss the spectral characteristics around 54-55 and 240 days after the 2006 outburst. In April 2006 most of the emission lines present a broad pedestal with a strong and narrow component at about -20 km s-1 and two other extended emission components at -200 and +150 km s-1. These components could originate in a bipolar gas outflow supporting the model

  17. Handbook of Basic Atomic Spectroscopic Data

    National Institute of Standards and Technology Data Gateway

    SRD 108 Handbook of Basic Atomic Spectroscopic Data (Web, free access)   This handbook provides a selection of the most important and frequently used atomic spectroscopic data. The compilation includes data for the neutral and singly-ionized atoms of all elements hydrogen through einsteinium (Z = 1-99). The wavelengths, intensities, and spectrum assignments are given for each element, and the data for the approximately 12,000 lines of all elements are also collected into a single table.

  18. HIPPARCOS PHOTOCENTRIC ORBITS OF 72 SINGLE-LINED SPECTROSCOPIC BINARIES

    SciTech Connect

    Ren Shulin; Fu Yanning E-mail: fyn@pmo.ac.cn

    2013-03-15

    By fitting the Hipparcos Intermediate Astrometric Data (HIAD), photocentric orbits can be obtained for the single-lined spectroscopic binaries (SB1s). In previous work, a simplifying approximation used in the fitting process was that the photocenter coincides with the primary, but simple arguments based on a mass-luminosity relation show that this approximation will introduce non-negligible deviation into photocentric orbits of a few SB1s. By fitting the revised HIAD without the approximation, the present paper tries to provide reliable photocentric orbits for those SB1s in the 9th Catalogue of Orbits of Spectroscopic Binaries having a reliable spectroscopic orbit of period between 50 days and 3.2 years. After a stringent assessment and screening process, we finally accept the photocentric orbits of 72 systems. Among these results, 37 orbits are obtained here for the first time. So far, only three of these systems are resolved with a known relative orbit. For each of them, the paired photocentric and relative orbits are in reasonably good agreement. For the 25 systems with a main-sequence primary, the masses of component stars and the semimajor axes of relative orbits are estimated for the purpose of planning ground-based observations.

  19. The Effect of Preoperative Subcutaneous Fat Thickness on Surgical Site Infection Risk in Patients Undergoing Colorectal Surgery: Results of a Multisite, Prospective Cohort Study.

    PubMed

    Nakagawa, Hiromi; Ohno, Kaori; Ikeda, Shunya; Muto, Masaki

    2016-08-01

    Surgical site infection (SSI) is one of the most frequent postoperative complications among patients undergoing elective colorectal surgery. A multisite, prospective cohort study was conducted to investigate whether the thickness of subcutaneous fat (TSF) influences the occurrence of SSI in patients undergoing colorectal surgery. Participants included patients scheduled to receive colorectal laparotomy for colorectal cancer and who were under the care of a wound ostomy continence nurse at 17 participating general hospitals in Japan. Patients were not eligible to participate if they had undergone emergency surgery, reoperation, or laparoscopic surgery. Demographic, wound, and surgical data and American Society of Anesthesiologists (ASA) scale scores were collected and assessed, along with nutritional status, TSF, body mass index, and risk factors for SSI (ie, length of surgery and wound classification). The incidence of SSI and nutritional conditions was assessed weekly for 30 days after surgery. Of the 155 participants (mean age 68.9 ± 10.8 years, 53 [34.2%] of whom were women), 90 (58.1%) underwent rectal surgery, and the remaining 65 underwent colon surgery. Seventy-two (72, 46.5%) of the 155 patients underwent colostomy surgery; 24 (15.5%) developed a SSI. The mean onset of SSI was 7.3 ± 2.9 days after surgery and commonly observed in the stoma group when the ASA score was 3 or higher (P = 0.02). Patients who developed SSI resumed oral dietary intake later than those without SSI (7.4 days versus 4.6 days, P = 0.02). Multivariate analysis indicated TSF >15 mm (P = 0.01), Alb level <3.5 g/dL at postoperative days 14 (P = 0.03) and 21 (P = 0.02), and total protein level <6.8 g/dL at postoperative day 7 (P = 0.02) were statistically significantly correlated with SSI occurrence. These results suggest preoperative TSF and preoperative and postoperative serum albumin levels are independent risk factors for SSI in patients undergoing colorectal surgery, confirming

  20. Multisite high resolution measurements of carbon monoxide along Greenland ice cores: evidence for in-situ production and potential for atmospheric reconstruction

    NASA Astrophysics Data System (ADS)

    Faïn, Xavier; Chappellaz, Jérôme; Rhodes, Rachael; Stowasser, Christopher; Blunier, Thomas; McConnell, Joseph; Brook, Edward; Desbois, Thibault; Romanini, Daniele

    2014-05-01

    Carbon monoxide (CO) is the principal sink for hydroxyl radicals (OH) in the troposphere. Consequently, changes in atmospheric CO levels can considerably perturb the oxidizing capacity of the atmosphere, affecting mixing ratios of a host of chemical species oxidized by OH, including methane. In addition, CO variations (and changes in its stable isotopic composition) are expected to be good tracers of changes in biomass burning emissions. Investigating past mixing ratios of carbon monoxide is thus a promising approach towards reducing uncertainty related to the past oxidative capacity of the atmosphere and biogeochemical cycling of methane. Recent developments in optical spectrometry (Optical Feedback Cavity Enhanced Absorption Spectrometry, OFCEAS), combined with continuous flow analysis (CFA) systems, allow efficient, precise measurements of CO concentrations in ice cores. Coupling our OFCEAS spectrometer with the CFA melter operated at DRI (Reno, USA) provided the first continuous CO measurements along the NEEM (Greenland) core covering the last 1800 yr at an unprecedented resolution. Although the most recent section of this record (i.e., since 1700 AD) agreed with existing discrete CO measurements from the Eurocore ice core and the deep NEEM firn, it was difficult to interpret in terms of atmospheric CO variation due to high frequency, high amplitudes spikes related to in-situ production (Faïn et al., Climate of the Past Discussion). During a recent 8-week analytical campaign, three different ice archives from Greenland were melted on the DRI CFA and analyzed continuously for CO with the OFCEAS spectrometer: (i) the D4 core (spanning the last 170 yr), (ii) the NEEM core (extending the existing record from 200 AD to 800 BC), and (iii) the Tunu core (spanning the last 1800 yr). Although in-situ production of CO is observed at all sites, these new records reveal different CO patterns and trends. This multisite approach allows us to better characterize the

  1. The Sydney Multisite Intervention of LaughterBosses and ElderClowns (SMILE) study: cluster randomised trial of humour therapy in nursing homes

    PubMed Central

    Low, Lee-Fay; Brodaty, Henry; Goodenough, Belinda; Spitzer, Peter; Bell, Jean-Paul; Fleming, Richard; Casey, Anne-Nicole; Liu, Zhixin; Chenoweth, Lynn

    2013-01-01

    Objectives To determine whether humour therapy reduces depression (primary outcome), agitation and behavioural disturbances and improves social engagement and quality-of-life in nursing home residents. Design The Sydney Multisite Intervention of LaughterBosses and ElderClowns study was a single-blind cluster randomised controlled trial of humour therapy. Setting 35 Sydney nursing homes. Participants All eligible residents within geographically defined areas within each nursing home were invited to participate. Intervention Professional ‘ElderClowns’ provided 9–12 weekly humour therapy sessions, augmented by resident engagement by trained staff ‘LaughterBosses’. Controls received usual care. Measurements Depression scores on the Cornell Scale for Depression in Dementia, agitation scores on the Cohen-Mansfield Agitation Inventory, behavioural disturbance scores on the Neuropsychiatric Inventory, social engagement scores on the withdrawal subscale of Multidimensional Observation Scale for Elderly Subjects, and self-rated and proxy-rated quality-of-life scores on a health-related quality-of-life tool for dementia, the DEMQOL. All outcomes were measured at the participant level by researchers blind to group assignment. Randomisation Sites were stratified by size and level of care then assigned to group using a random number generator. Results Seventeen nursing homes (189 residents) received the intervention and 18 homes (209 residents) received usual care. Groups did not differ significantly over time on the primary outcome of depression, or on behavioural disturbances other than agitation, social engagement and quality of life. The secondary outcome of agitation was significantly reduced in the intervention group compared with controls over 26 weeks (time by group interaction adjusted for covariates: p=0.011). The mean difference in change from baseline to 26 weeks in Blom-transformed agitation scores after adjustment for covariates was 0.17 (95% CI 0

  2. Using Spectroscopic Profiles to Study the Morphology of Comets

    NASA Astrophysics Data System (ADS)

    Harris, Ien; Pierce, Donna M.; Cochran, Anita L.

    2016-10-01

    We have used the integral-field unit spectrograph (the George and Cynthia Mitchell Spectrograph) on the 2.7m Harlan J. Smith telescope at McDonald Observatory to obtain spectroscopic images of the comae of several comets. The images were obtained for various radical species (C2, C3. CH, CN, NH2). Radial and azimuthal average profiles of the radical species were created to enhance any observed cometary coma morphological features. We compare the observed coma features across the observed species and over the different observation periods in order to constrain possible rotational states of the observed comets. We will present results for several comets, including 2009P1 (Garradd). This work was funded by NASA's Planetary Atmospheres program (Award No. NNX14AH186).

  3. Tissue classification of large-scale multi-site MR data using fuzzy k-nearest neighbor method

    NASA Astrophysics Data System (ADS)

    Ghayoor, Ali; Paulsen, Jane S.; Kim, Regina E. Y.; Johnson, Hans J.

    2016-03-01

    This paper describes enhancements to automate classification of brain tissues for multi-site degenerative magnetic resonance imaging (MRI) data analysis. Processing of large collections of MR images is a key research technique to advance our understanding of the human brain. Previous studies have developed a robust multi-modal tool for automated tissue classification of large-scale data based on expectation maximization (EM) method initialized by group-wise prior probability distributions. This work aims to augment the EM-based classification using a non-parametric fuzzy k-Nearest Neighbor (k-NN) classifier that can model the unique anatomical states of each subject in the study of degenerative diseases. The presented method is applicable to multi-center heterogeneous data analysis and is quantitatively validated on a set of 18 synthetic multi-modal MR datasets having six different levels of noise and three degrees of bias-field provided with known ground truth. Dice index and average Hausdorff distance are used to compare the accuracy and robustness of the proposed method to a state-of-the-art classification method implemented based on EM algorithm. Both evaluation measurements show that presented enhancements produce superior results as compared to the EM only classification.

  4. Multi-site videoconferencing for home-based education of older people with chronic conditions: the Telehealth Literacy Project.

    PubMed

    Banbury, Annie; Parkinson, Lynne; Nancarrow, Susan; Dart, Jared; Gray, Len; Buckley, Jennene

    2014-10-01

    We examined the acceptability of multi-site videoconferencing as a method of providing group education to older people in their homes. There were 9 groups comprising 52 participants (mean age 73 years) with an average of four chronic conditions. Tablet computers or PCs were installed in participant's homes and connected to the Internet by the National Broadband Network (high-speed broad band network) or by the 4G wireless network. A health literacy and self-management programme was delivered by videoconference for 5 weeks. Participants were able to view and interact with all group members and the facilitator on their devices. During the study, 44 group videoconferences were conducted. Evaluation included 16 semi-structured interviews, 3 focus groups and a journal detailing project implementation. The participants reported enjoying home-based group education by videoconference and found the technology easy to use. Using home-based groups via videoconference was acceptable for providing group education, and considered particularly valuable for people living alone and/or with limited mobility. Audio difficulties were the most commonly reported problem. Participants connected with 4G experienced more problems (audio and visual) than participants on the National Broadband Network and those living in multi-dwelling residences reported more problems than those living in single-dwelling residences. Older people with little computer experience can be supported to use telehealth equipment. Telehealth has the potential to improve access to education about chronic disease self-management.

  5. Provision of pandemic disease information by health sciences librarians: a multisite comparative case series*†‡§

    PubMed Central

    Featherstone, Robin M; Boldt, R. Gabriel; Torabi, Nazi; Konrad, Shauna-Lee

    2012-01-01

    Objective: The research provides an understanding of pandemic information needs and informs professional development initiatives for librarians in disaster medicine. Methods: Utilizing a multisite, comparative case series design, the researchers conducted semi-structured interviews and examined supplementary materials in the form of organizational documents, correspondence, and websites to create a complete picture of each case. The rigor of the case series was ensured through data and investigator triangulation. Interview transcripts were coded using NVivo to identify common themes and points of comparison. Results: Comparison of the four cases revealed a distinct difference between “client-initiated” and “librarian-initiated” provision of pandemic information. Librarian-initiated projects utilized social software to “push” information, whereas client-initiated projects operated within patron-determined parameters to deliver information. Health care administrators were identified as a key audience for pandemic information, and news agencies were utilized as essential information sources. Librarians' skills at evaluating available information proved crucial for selecting best-quality evidence to support administrative decision making. Conclusions: Qualitative analysis resulted in increased understanding of pandemic information needs and identified best practices for disseminating information during periods of high organizational stress caused by an influx of new cases of an unknown infectious disease. PMID:22514506

  6. Causal Interactions Within a Frontal-Cingulate-Parietal Network During Cognitive Control: Convergent Evidence from a Multisite-Multitask Investigation.

    PubMed

    Cai, Weidong; Chen, Tianwen; Ryali, Srikanth; Kochalka, John; Li, Chiang-Shan R; Menon, Vinod

    2016-05-01

    Cognitive control plays an important role in goal-directed behavior, but dynamic brain mechanisms underlying it are poorly understood. Here, using multisite fMRI data from over 100 participants, we investigate causal interactions in three cognitive control tasks within a core Frontal-Cingulate-Parietal network. We found significant causal influences from anterior insula (AI) to dorsal anterior cingulate cortex (dACC) in all three tasks. The AI exhibited greater net causal outflow than any other node in the network. Importantly, a similar pattern of causal interactions was uncovered by two different computational methods for causal analysis. Furthermore, the strength of causal interaction from AI to dACC was greater on high, compared with low, cognitive control trials and was significantly correlated with individual differences in cognitive control abilities. These results emphasize the importance of the AI in cognitive control and highlight its role as a causal hub in the Frontal-Cingulate-Parietal network. Our results further suggest that causal signaling between the AI and dACC plays a fundamental role in implementing cognitive control and are consistent with a two-stage cognitive control model in which the AI first detects events requiring greater access to cognitive control resources and then signals the dACC to execute load-specific cognitive control processes. PMID:25778346

  7. The BHIVES collaborative: organization and evaluation of a multisite demonstration of integrated buprenorphine/naloxone and HIV treatment.

    PubMed

    Weiss, Linda; Egan, James E; Botsko, Michael; Netherland, Julie; Fiellin, David A; Finkelstein, Ruth

    2011-03-01

    Substance abuse is associated with poor medical and quality-of-life outcomes among HIV-infected individuals. Although drug treatment may reduce these negative consequences, for many patients, options are limited. Buprenorphine/naloxone, an opioid agonist treatment that can be prescribed in the United States in office-based settings, can be used to expand treatment capacity and integrate substance abuse services into HIV care. Recognizing this potential, the US Health Resources and Services Administration funded the development and implementation of demonstration projects that integrated HIV care and buprenorphine/naloxone treatment at 10 sites across the country. An Evaluation and Technical Assistance Center provided programmatic and clinical support as well as oversight for an evaluation that examined the processes for and outcomes of integrated care. The evaluation included patient-level self-report and chart abstractions as well as provider and site level data collected through surveys and in-depth interviews. Although multisite demonstrations pose implementation and evaluation challenges, our experience demonstrates that these can, in part, be addressed through ongoing communication and technical assistance as well as a comprehensive evaluation design that incorporates multiple research methods and data sources. Although limitations to evaluation findings persist, they may be balanced by the scope and "real-world" context of the initiative. PMID:21317598

  8. Minimal Models for Cell-Cycle Control Based on Competitive Inhibition and Multisite Phosphorylations of Cdk Substrates

    PubMed Central

    Gérard, Claude; Tyson, John J.; Novák, Béla

    2013-01-01

    The eukaryotic cell cycle is characterized by alternating oscillations in the activities of cyclin-dependent kinase (Cdk) and the anaphase-promoting complex (APC). Successful completion of the cell cycle is dependent on the precise, temporally ordered appearance of these activities. A modest level of Cdk activity is sufficient to initiate DNA replication, but mitosis and APC activation require an elevated Cdk activity. In present-day eukaryotes, this temporal order is provided by a complex network of regulatory proteins that control both Cdk and APC activities via sharp thresholds, bistability, and time delays. Using simple computational models, we show here that these dynamical features of cell-cycle organization could emerge in a control system driven by a single Cdk/cyclin complex and APC wired in a negative-feedback loop. We show that ordered phosphorylation of cellular proteins could be explained by multisite phosphorylation/dephosphorylation and competition of substrates for interconverting kinase (Cdk) and phosphatase. In addition, the competition of APC substrates for ubiquitylation can create and maintain sustained oscillations in cyclin levels. We propose a sequence of models that gets closer and closer to a realistic model of cell-cycle control in yeast. Since these models lack the elaborate control mechanisms characteristic of modern eukaryotes, they suggest that bistability and time delay may have characterized eukaryotic cell divisions before the current cell-cycle control network evolved in all its complexity. PMID:23528096

  9. Autoinhibition and Polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase Haspin to mitosis

    PubMed Central

    Ghenoiu, Cristina; Wheelock, Michael S.; Funabiki, Hironori

    2013-01-01

    SUMMARY The mitosis-specific phosphorylation of Histone H3 at Thr3 (H3T3ph) plays an important role in chromosome segregation by recruiting Aurora B. H3T3 phosphorylation is catalyzed by Haspin, an atypical protein kinase, whose kinase domain is intrinsically active without phosphorylation at the activation loop. We report here the molecular basis for Haspin inhibition during interphase and its reactivation in M phase. We identify a conserved basic segment that autoinhibits Haspin during interphase. This autoinhibition is neutralized when Cdk1 phosphorylates the N terminus of Haspin to recruit Polo-like kinase (Plk1/Plx1), which in turn further phosphorylates multiple sites at the Haspin N terminus. While Plx1, but not Aurora B, is critical for H3T3 phosphorylation in Xenopus egg extracts, Plk1 and Aurora B both promote this modification in human cells. Thus, M phase-specific H3T3 phosphorylation is governed by the combinatorial action of mitotic kinases that neutralizes Haspin autoinhibition through a mechanism dependent on multisite phosphorylation. PMID:24184212

  10. Autoinhibition and Polo-dependent multisite phosphorylation restrict activity of the histone H3 kinase Haspin to mitosis.

    PubMed

    Ghenoiu, Cristina; Wheelock, Michael S; Funabiki, Hironori

    2013-12-12

    The mitosis-specific phosphorylation of histone H3 at Thr3 (H3T3ph) plays an important role in chromosome segregation by recruiting Aurora B. H3T3 phosphorylation is catalyzed by Haspin, an atypical protein kinase whose kinase domain is intrinsically active without phosphorylation at the activation loop. Here, we report the molecular basis for Haspin inhibition during interphase and its reactivation in M phase. We identify a conserved basic segment that autoinhibits Haspin during interphase. This autoinhibition is neutralized when Cdk1 phosphorylates the N terminus of Haspin in order to recruit Polo-like kinase (Plk1/Plx1), which, in turn, further phosphorylates multiple sites at the Haspin N terminus. Although Plx1, and not Aurora B, is critical for H3T3 phosphorylation in Xenopus egg extracts, Plk1 and Aurora B both promote this modification in human cells. Thus, M phase-specific H3T3 phosphorylation is governed by the combinatorial action of mitotic kinases that neutralizes Haspin autoinhibition through a mechanism dependent on multisite phosphorylation. PMID:24184212

  11. Motivational interviewing to improve treatment engagement and outcome in individuals seeking treatment for substance abuse: A multisite effectiveness study

    PubMed Central

    Carroll, Kathleen M.; Ball, Samuel A.; Nich, Charla; Martino, Steve; Frankforter, Tami L.; Farentinos, Christiane; Kunkel, Lynn E.; Mikulich-Gilbertson, Susan K.; Morgenstern, Jon; Obert, Jeanne L.; Polcin, Doug; Snead, Ned; Woody, George E.

    2008-01-01

    Despite recent emphasis on integrating empirically validated treatment into clinical practice, there are little data on whether manual-guided behavioral therapies can be implemented in standard clinical practice and whether incorporation of such techniques is associated with improved outcomes. The effectiveness of integrating motivational interviewing (MI) techniques into the initial contact and evaluation session was evaluated in a multisite randomized clinical trial. Participants were 423 substance users entering outpatient treatment in five community-based treatment settings, who were randomized to receive either the standard intake/evaluation session at each site or the same session in which MI techniques and strategies were integrated. Clinicians were drawn from the staff of the participating programs and were randomized either to learn and implement MI or to deliver the standard intake/evaluation session. Independent analyses of 315 session audiotapes suggested the two forms of treatment were highly discriminable and that clinicians trained to implement MI tended to have higher skill ratings. Regarding outcomes, for the sample as a whole, participants assigned to MI had significantly better retention through the 28-day follow-up than those assigned to the standard intervention. There were no significant effects of MI on substance use outcomes at either the 28-day or 84-day follow-up. Results suggest that community-based clinicians can effectively implement MI when provided training and supervision, and that integrating MI techniques in the earliest phases of treatment may have positive effects on retention early in the course of treatment. PMID:16169159

  12. Control of microtubule dynamics by oncoprotein 18: dissection of the regulatory role of multisite phosphorylation during mitosis.

    PubMed Central

    Larsson, N; Marklund, U; Gradin, H M; Brattsand, G; Gullberg, M

    1997-01-01

    Oncoprotein 18 (Op18; also termed p19, 19K, metablastin, stathmin, and prosolin) is a conserved protein that regulates microtubule (MT) dynamics. Op18 is multisite phosphorylated on four Ser residues during mitosis; two of these Ser residues, Ser-25 and Ser-38, are targets for cyclin-dependent protein kinases (CDKs), and the other two Ser residues, Ser-16 and Ser-63, are targets for an unidentified protein kinase. Mutations of the two CDK sites have recently been shown to result in a mitotic block caused by destabilization of MTs. To understand the role of Op18 in regulation of MT dynamics during mitosis, in this study we dissected the functions of all four phosphorylation sites of Op18 by combining genetic, morphological, and biochemical analyses. The data show that all four phosphorylation sites are involved in switching off Op18 activity during mitosis, an event that appears to be essential for formation of the spindle during metaphase. However, the mechanisms by which specific sites down-regulate Op18 activity differ. Hence, dual phosphorylation on the CDK sites Ser-25 and Ser-38 appears to be required for phosphorylation of Ser-16 and Ser-63; however, by themselves, the CDK sites are of only minor importance in direct regulation of Op18 activity. Subsequent phosphorylation of either Ser-16, Ser-63, or both efficiently switches off Op18 activity. PMID:9271428

  13. Child sexual abuse prevention training for childcare professionals: an independent multi-site randomized controlled trial of Stewards of Children.

    PubMed

    Rheingold, Alyssa A; Zajac, Kristyn; Chapman, Jason E; Patton, Meghan; de Arellano, Michael; Saunders, Benjamin; Kilpatrick, Dean

    2015-04-01

    Given the significant rates and deleterious consequences of childhood sexual abuse (CSA), identifying effective primary prevention approaches is a clear priority. There isa growing awareness that childcare professionals (e.g.,teachers, childcare personnel, clergy) are in a unique position to engage in prevention efforts due to high accessibility to children and expertise in child development. However, CSA prevention programs targeting childcare professionals have received insufficient attention. The goal of this study was toc on duct an independent multi-site controlled evaluation of an existing CSA prevention program, Stewards of Children, offered through both in-person and web-based formats. This study included 352 childcare professionals recruited from children’s advocacy centers across three states. Participants were randomly assigned to one of three conditions: (1) inperson training, (2) web-based training, or (3) waitlist control. Dependent variables included CSA knowledge, CSA attitudes,and self-reported CSA preventive behaviors. Results indicated that Stewards impacted knowledge, attitudes, and preventive behaviors. No differences were found between training modalities (i.e., in-person versus web-based) on knowledge and preventive behaviors. Results indicate that brief trainings for childcare professionals may impact CSA prevention efforts.

  14. The galaxy population of Abell 1367: photometric and spectroscopic data

    NASA Astrophysics Data System (ADS)

    Kriwattanawong, W.; Moss, C.; James, P. A.; Carter, D.

    2011-03-01

    Aims: Photometric and spectroscopic observations of the galaxy population of the galaxy cluster Abell 1367 have been obtained, over a field of 34' × 90', covering the cluster centre out to a radius of ~2.2 Mpc. Optical broad- and narrow-band imaging was used to determine galaxy luminosities, diameters and morphologies, and to study current star formation activity of a sample of cluster galaxies. Near-infrared imaging was obtained to estimate integrated stellar masses, and to aid the determination of mean stellar ages and metallicities for the future investigation of the star formation history of those galaxies. Optical spectroscopic observations were also taken, to confirm cluster membership of galaxies in the sample through their recession velocities. Methods.U, B and R broad-band and Hα narrow-band imaging observations were carried out using the Wide Field Camera (WFC) on the 2.5 m Isaac Newton Telescope on La Palma, covering the field described above. J and K near-infrared imaging was obtained using the Wide Field Camera (WFCAM) on the 3.8 m UK Infrared Telescope on Mauna Kea, covering a somewhat smaller field of 0.75 square degrees on the cluster centre. The spectroscopic observations were carried out using a multifibre spectrograph (WYFFOS) on the 4.2 m William Herschel Telecope on La Palma, over the same field as the optical imaging observations. Results: Our photometric data give optical and near-infrared isophotal magnitudes for 303 galaxies in our survey regions, down to stated diameter and B-band magnitude limits, determined within R24 isophotal diameters. Our spectroscopic data of 328 objects provide 84 galaxies with detections of emission and/or absorption lines. Combining these with published spectroscopic data gives 126 galaxies within our sample for which recession velocities are known. Of these, 72 galaxies are confirmed as cluster members of Abell 1367, 11 of which are identified in this study and 61 are reported in the literature. Hα equivalent

  15. Picosecond flash spectroscopic studies on ultraviolet stabilizers and stabilized polymers

    NASA Technical Reports Server (NTRS)

    Scott, G. W.

    1982-01-01

    Spectroscopic and excited state decay kinetics are reported for monomeric and polymeric forms of ultraviolet stabilizers in the 2-(2'-hydroxyphenyl)-benzotriazole and 2-hydroxybenzophenone classes. For some of these molecules in various solvents at room temperature, (1) ground state absorption spectra, (2) emission spectra, (3) picosecond time-resolved transient absorption spectra, (4) ground state absorption recovery kinetics, (5) emission kinetics, and (6) transient absorption kinetics are reported. In the solid state at low temperatures, emission spectra and their temperature dependent kinetics up to approximately 200K as well as, in one case, the 12K excitation spectra of the observed dual emission are also reported.

  16. VizieR Online Data Catalog: GEEC2 spectroscopic survey of Galaxy groups (Balogh+, 2014)

    NASA Astrophysics Data System (ADS)

    Balogh, M. L.; McGee, S. L.; Mok, A.; Wilman, D. J.; Finoguenov, A.; Bower, R. G.; Mulchaey, J. S.; Parker, L. C.; Tanaka, M.

    2015-04-01

    GEEC2 is a spectroscopic survey of galaxies in 11 groups, one of which was serendipitously discovered in the background of the target, within the COSMOS field. The spectroscopy was obtained with GMOS-South over two semesters (2010A and 2011A). The original goal of the survey was to observe ~20 groups, with 3-4 spectroscopic masks each, to allow an investigation of the intrinsic scatter within group populations. However, repeated attempts to complete the programme have been thwarted by bad weather, scheduling conflicts at Gemini, and variance in ranking from semester to semester. Following the lack of any time awarded in 2012B, attempts to extend the sample have been abandoned for the moment. Details of the target selection and spectroscopic observations have been presented in Papers I-III. (4 data files).

  17. Spectroscopic indicators of life on other planets

    NASA Astrophysics Data System (ADS)

    Kasting, James F.

    2008-10-01

    Astronomers have now identified over 300 extrasolar planets orbiting nearby stars. Most of these planets have been found by using ground-based instruments to measure Doppler shifts in the spectrum of the parent star. For stars similar to our Sun, this method is unable to find planets as small as Earth. Within the next two (three?) decades, however, NASA hopes to launch space-based telescopes that will be able to search directly for extrasolar planets. NASA's planned Terrestrial Planet Finder (TPF) missions, will look for Earth-like planets around nearby stars and, if they exist, provide spectroscopic information on their atmospheres. TPF-C will be a coronagraph that operates in the visible/near-IR. A variant of this idea, called TPF-O, would replace the internal coronagraph with a free-flying occulting disk. TPF-I is envisioned as a free-flying interferometer operating in the thermal-IR. On a planet like modern Earth, TPF-C or TPF--O should be able to see absorption bands of O2, H2O, and possibly O3. TPF-I would be able to see CO2, H2O, and O3. Both O2 and O3 are considered to be good indicators of life for planets orbiting within the liquid water habitable zone of their parent star. Even better evidence for life would be the simultaneous observation of O2 (or O3) and a reduced gas such as CH4 or N2O. That may not be possible with a first-generation TPF instrument but should ultimately be possible in the more distant future.

  18. The SPHEREx All-Sky Spectroscopic Survey

    NASA Astrophysics Data System (ADS)

    Unwin, Stephen C.; SPHEREx Science Team, SPHEREx Project Team

    2016-06-01

    SPHEREx is a mission to conduct an optical-near-IR survey of the entire sky with a spectrum at every pixel location. It was selected by NASA for a Phase A study in its Small Explorer Program; if selected, development would begin in 2016, and the observatory would start a 2-year prime mission in 2020. An all-sky spectroscopic survey can be used to tackle a wide range of science questions. The SPHEREx science team is focusing on three: (1) Probing the physics of inflation through measuring non-Gaussianity from the study of large-scale structure; (2) Studying the origin of water and biogenic molecules in a wide range of physical and chemical environments via ice absorption spectra; (3) Charting the history of star formation in the universe through intensity mapping of the large-scale spatial power. The instrument is a small wide-field telescope operating in the range of 0.75 - 4.8 µm at a spectral resolution of 41.5 in the optical and 150 at the long-wavelength end. It observes in a sun-sync low-earth orbit, covering the sky like WISE and COBE. SPHEREx is a simple instrument that requires no new technology. The Phase A design has substantial technical and resource margins and can be built with low risk. It is a partnership between Caltech and JPL, with Ball Aerospace and the Korea Astronomy and Space Science Institute as major partners. This research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration.

  19. The SPHEREx All-Sky Spectroscopic Survey

    NASA Astrophysics Data System (ADS)

    Unwin, Stephen C.; SPHEREx Science Team, SPHEREx Project Team

    2016-06-01

    SPHEREx is a mission to conduct an optical-near-IR survey of the entire sky with a spectrum at every pixel location. It was selected by NASA for a Phase A study in its Small Explorer Program; if selected, development would begin in 2016, and the observatory would start a 2-year prime mission in 2020. An all-sky spectroscopic survey can be used to tackle a wide range of science questions. The SPHEREx science team is focusing on three: (1) Probing the physics of inflation through measuring non-Gaussianity from the study of large-scale structure; (2) Studying the origin of water and biogenic molecules in a wide range of physical and chemical environments via ice absorption spectra; (3) Charting the history of star formation in the universe through intensity mapping of the large-scale spatial power. The instrument is a small wide-field telescope operating in the range of 0.75 - 4.8 µm at a spectral resolution of 41.5 in the optical and 150 at the long-wavelength end. It observes in a sun-sync low-earth orbit, covering the sky like WISE and COBE. SPHEREx is a simple instrument that requires no new technology. The Phase A design has substantial technical and resource margins and can be built with low risk. It is a partnership between Caltech and JPL, with Ball Aerospace and the Korea Astronomy and Space Science Institute as major partners. This research was carried out at the Jet Propulsion Laboratory, California Institute of Technology, under a contract with the National Aeronautics and Space Administration. © 2016 California Institute of Technology. Government sponsorship acknowledged.

  20. Optical Spectroscopic Monitoring of Parachute Yarn Aging

    SciTech Connect

    Tallant, D.R.; Garcia, M.J.; Simpson, R.L.; Behr, V.L.; Whinery, L.D.; Peng, L.W.

    1999-04-01

    Optical spectroscopic techniques were evaluated as nondestructive monitors of the aging of parachutes in nuclear weapons. We analyzed thermally aged samples of nylon and Kevlar webbing by photoluminescence spectroscopy and reflection spectroscopy. Infrared analysis was also performed to help understand the degradation mechanisms of the polymer materials in the webbing. The photoluminescence and reflection spectra were analyzed by chemometric data treatment techniques to see if aged-induced changes in the spectra correlated to changes in measured tensile strength. A correlation was found between the shapes of the photoluminescent bands and the measured tensile strengths. Photoluminescent spectra can be used to predict the tensile strengths of nylon and Kevlar webbing with sufficient accuracy to categorize the webbing sample as above rated tensile strength, marginal or below rated tensile strength. The instrumentation required to perform the optical spectroscopic measurement can be made rugged, compact and portable. Thus, optical spectroscopic techniques offer a means for nondestructive field monitoring of parachutes in the enduring stockpile/

  1. Spectroscopic survey of M-type asteroids

    NASA Astrophysics Data System (ADS)

    Fornasier, S.; Clark, B. E.; Dotto, E.; Migliorini, A.; Ockert-Bell, M.; Barucci, M. A.

    2010-12-01

    M-type asteroids, as defined in the Tholen taxonomy (Tholen, D.J. [1984]. Asteroid Taxonomy from Cluster Analysis of Photometry. Ph.D. Dissertation, University of Arizona, Tucson), are medium albedo bodies supposed to have a metallic composition and to be the progenitors both of differentiated iron-nickel meteorites and enstatite chondrites. We carried out a spectroscopic survey in the visible and near infrared wavelength range (0.4-2.5 μm) of 30 asteroids chosen from the population of asteroids initially classified as Tholen M-types, aiming to investigate their surface composition. The data were obtained during several observing runs during the years 2004-2007 at the TNG, NTT, and IRTF telescopes. We computed the spectral slopes in several wavelength ranges for each observed asteroid, and we searched for diagnostic spectral features. We confirm a large variety of spectral behaviors for these objects as their spectra are extended into the near infrared, including the identification of weak absorption bands, mainly of the 0.9 μm band tentatively attributed to orthopyroxene, and of the 0.43 μm band that may be associated to chlorites and Mg-rich serpentines or pyroxene minerals such us pigeonite or augite. A comparison with previously published data indicates that the surfaces of several asteroids belonging to the M-class may vary significantly. We attempt to constrain the asteroid surface compositions of our sample by looking for meteorite spectral analogs in the RELAB database and by modeling with geographical mixtures of selected meteorites/minerals. We confirm that iron meteorites, pallasites, and enstatite chondrites are the best matches to most objects in our sample, as suggested for M-type asteroids. For 22 Kalliope, we demonstrate that a synthetic mixture obtained enriching a pallasite meteorite with small amounts (1-2%) of silicates well reproduce the spectral behavior including the observed 0.9 μm feature. The presence of subtle absorption features on

  2. A SPECTROSCOPIC CENSUS OF THE M82 STELLAR CLUSTER POPULATION

    SciTech Connect

    Konstantopoulos, I. S.; Westmoquette, M. S.; Bastian, N.; Smith, L. J.; Trancho, G.

    2009-08-20

    We present a spectroscopic study of the stellar cluster population of M82, the archetype starburst galaxy, based primarily on new Gemini-North multi-object spectroscopy of 49 star clusters. These observations constitute the largest to date spectroscopic data set of extragalactic young clusters, giving virtually continuous coverage across the galaxy; we use these data to deduce information about the clusters as well as the M82 post-starburst disk and nuclear starburst environments. Spectroscopic age dating places clusters in the nucleus and disk between (7, 15) and (30, 270) Myr, with distribution peaks at {approx}10 and 140 Myr, respectively. We find cluster radial velocities (RVs) in the range v{sub R} in (-160, 220)km s{sup -1} (with respect to the galaxy center), and line-of-sight Na I D interstellar absorption line velocities v {sup NaID}{sub R} in (-75, 200) km s{sup -1}, in many cases entirely decoupled from the clusters. As the disk cluster RVs lie on the flat part of the galaxy rotation curve, we conclude that they comprise a regularly orbiting system. Our observations suggest that the largest part of the population was created as a result of the close encounter with M81 {approx}220 Myr ago. Clusters in the nucleus are found in solid body rotation on the bar. The possible detection of Wolf-Rayet features in their spectra indicates that cluster formation continues in the central starburst zone. We also report the potential discovery of two old populous clusters in the halo of M82, aged {approx}>8 Gyr. Using these measurements and simple dynamical considerations, we derive a toy model for the invisible physical structure of the galaxy, and confirm the existence of two dominant spiral arms.

  3. THE BARYON OSCILLATION SPECTROSCOPIC SURVEY OF SDSS-III

    SciTech Connect

    Dawson, Kyle S.; Ahn, Christopher P.; Bolton, Adam S.; Schlegel, David J.; Bailey, Stephen; Anderson, Scott F.; Bhardwaj, Vaishali; Aubourg, Eric; Bautista, Julian E.; Beifiori, Alessandra; Berlind, Andreas A.; Bizyaev, Dmitry; Brewington, Howard; Blake, Cullen H.; Blanton, Michael R.; Blomqvist, Michael; Borde, Arnaud; Brandt, W. N.; and others

    2013-01-01

    The Baryon Oscillation Spectroscopic Survey (BOSS) is designed to measure the scale of baryon acoustic oscillations (BAO) in the clustering of matter over a larger volume than the combined efforts of all previous spectroscopic surveys of large-scale structure. BOSS uses 1.5 million luminous galaxies as faint as i = 19.9 over 10,000 deg{sup 2} to measure BAO to redshifts z < 0.7. Observations of neutral hydrogen in the Ly{alpha} forest in more than 150,000 quasar spectra (g < 22) will constrain BAO over the redshift range 2.15 < z < 3.5. Early results from BOSS include the first detection of the large-scale three-dimensional clustering of the Ly{alpha} forest and a strong detection from the Data Release 9 data set of the BAO in the clustering of massive galaxies at an effective redshift z = 0.57. We project that BOSS will yield measurements of the angular diameter distance d{sub A} to an accuracy of 1.0% at redshifts z = 0.3 and z = 0.57 and measurements of H(z) to 1.8% and 1.7% at the same redshifts. Forecasts for Ly{alpha} forest constraints predict a measurement of an overall dilation factor that scales the highly degenerate D{sub A} (z) and H {sup -1}(z) parameters to an accuracy of 1.9% at z {approx} 2.5 when the survey is complete. Here, we provide an overview of the selection of spectroscopic targets, planning of observations, and analysis of data and data quality of BOSS.

  4. Spectroscopic studies on aquatic angiosperm

    NASA Astrophysics Data System (ADS)

    Ozawa, Atsumi; Oomizo, Nana; Fujinami, Rieko; Imaichi, Ryoko; Imai, Hajime

    2011-01-01

    Reflectance, transmittance and absorbance spectra were observed of Hydrobryum japonicum, a kind of Aquatic angiosperm, over the wavelength range from 300 to 780 nm. Three remarkable peaks were observed at 380, 430, and at 680 nm in the absorbance curve, which were assigned to the two pigments flavonoid and chlorophyll. The functions of these pigments of making photosynthesis inevitable for the botanical activity and of protecting the plant from the heat given by the sunlight were discussed.

  5. Hierarchical Models of Social Competence in Preschool Children: A Multisite, Multinational Study

    ERIC Educational Resources Information Center

    Vaughn, Brian E.; Shin, Nana; Kim, Mina; Coppola, Gabrielle; Krzysik, Lisa; Santos, Antonio J.; Peceguina, Ines; Daniel, Joao R.; Verissimo, Manuela; DeVries, Anthon; Elphick, Eric; Ballentina, Xiomara; Bost, Kelly K.; Newell, Wanda Y.; Miller, Ellaine B.; Snider, J. Blake; Korth, Byran

    2009-01-01

    The generality of a multilevel factorial model of social competence (SC) for preschool children was tested in a 5-group, multinational sample (N = 1,540) using confirmatory factor analysis. The model fits the observed data well, and tests constraining paths for measured variables to their respective first-order factors across samples also fit…

  6. A multi-site stochastic weather generator of daily precipitation and temperature

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Stochastic weather generators are used to generate time series of climate variables that have statistical properties similar to those of observed data. Most stochastic weather generators work for a single site, and can only generate climate data at a single point, or independent time series at sever...

  7. Multisite longitudinal reliability of tract-based spatial statistics in diffusion tensor imaging of healthy elderly subjects.

    PubMed

    Jovicich, Jorge; Marizzoni, Moira; Bosch, Beatriz; Bartrés-Faz, David; Arnold, Jennifer; Benninghoff, Jens; Wiltfang, Jens; Roccatagliata, Luca; Picco, Agnese; Nobili, Flavio; Blin, Oliver; Bombois, Stephanie; Lopes, Renaud; Bordet, Régis; Chanoine, Valérie; Ranjeva, Jean-Philippe; Didic, Mira; Gros-Dagnac, Hélène; Payoux, Pierre; Zoccatelli, Giada; Alessandrini, Franco; Beltramello, Alberto; Bargalló, Núria; Ferretti, Antonio; Caulo, Massimo; Aiello, Marco; Ragucci, Monica; Soricelli, Andrea; Salvadori, Nicola; Tarducci, Roberto; Floridi, Piero; Tsolaki, Magda; Constantinidis, Manos; Drevelegas, Antonios; Rossini, Paolo Maria; Marra, Camillo; Otto, Josephin; Reiss-Zimmermann, Martin; Hoffmann, Karl-Titus; Galluzzi, Samantha; Frisoni, Giovanni B

    2014-11-01

    Large-scale longitudinal neuroimaging studies with diffusion imaging techniques are necessary to test and validate models of white matter neurophysiological processes that change in time, both in healthy and diseased brains. The predictive power of such longitudinal models will always be limited by the reproducibility of repeated measures acquired during different sessions. At present, there is limited quantitative knowledge about the across-session reproducibility of standard diffusion metrics in 3T multi-centric studies on subjects in stable conditions, in particular when using tract based spatial statistics and with elderly people. In this study we implemented a multi-site brain diffusion protocol in 10 clinical 3T MRI sites distributed across 4 countries in Europe (Italy, Germany, France and Greece) using vendor provided sequences from Siemens (Allegra, Trio Tim, Verio, Skyra, Biograph mMR), Philips (Achieva) and GE (HDxt) scanners. We acquired DTI data (2 × 2 × 2 mm(3), b = 700 s/mm(2), 5 b0 and 30 diffusion weighted volumes) of a group of healthy stable elderly subjects (5 subjects per site) in two separate sessions at least a week apart. For each subject and session four scalar diffusion metrics were considered: fractional anisotropy (FA), mean diffusivity (MD), radial diffusivity (RD) and axial (AD) diffusivity. The diffusion metrics from multiple subjects and sessions at each site were aligned to their common white matter skeleton using tract-based spatial statistics. The reproducibility at each MRI site was examined by looking at group averages of absolute changes relative to the mean (%) on various parameters: i) reproducibility of the signal-to-noise ratio (SNR) of the b0 images in centrum semiovale, ii) full brain test-retest differences of the diffusion metric maps on the white matter skeleton, iii) reproducibility of the diffusion metrics on atlas-based white matter ROIs on the white matter skeleton. Despite the differences of MRI scanner

  8. Multisite-specific archaeosine tRNA-guanine transglycosylase (ArcTGT) from Thermoplasma acidophilum, a thermo-acidophilic archaeon.

    PubMed

    Kawamura, Takuya; Hirata, Akira; Ohno, Satoshi; Nomura, Yuichiro; Nagano, Tomoko; Nameki, Nobukazu; Yokogawa, Takashi; Hori, Hiroyuki

    2016-02-29

    Archaeosine (G(+)), which is found only at position 15 in many archaeal tRNA, is formed by two steps, the replacement of the guanine base with preQ0 by archaeosine tRNA-guanine transglycosylase (ArcTGT) and the subsequent modification of preQ0 to G(+) by archaeosine synthase. However, tRNA(Leu) from Thermoplasma acidophilum, a thermo-acidophilic archaeon, exceptionally has two G(+)13 and G(+)15 modifications. In this study, we focused on the biosynthesis mechanism of G(+)13 and G(+)15 modifications in this tRNA(Leu). Purified ArcTGT from Pyrococcus horikoshii, for which the tRNA recognition mechanism and structure were previously characterized, exchanged only the G15 base in a tRNA(Leu) transcript with (14)C-guanine. In contrast, T. acidophilum cell extract exchanged both G13 and G15 bases. Because T. acidophilum ArcTGT could not be expressed as a soluble protein in Escherichia coli, we employed an expression system using another thermophilic archaeon, Thermococcus kodakarensis. The arcTGT gene in T. kodakarensis was disrupted, complemented with the T. acidophilum arcTGT gene, and tRNA(Leu) variants were expressed. Mass spectrometry analysis of purified tRNA(Leu) variants revealed the modifications of G(+)13 and G(+)15 in the wild-type tRNA(Leu). Thus, T. acidophilum ArcTGT has a multisite specificity and is responsible for the formation of both G(+)13 and G(+)15 modifications.

  9. A multi-site, randomized study of strengths-based case management with substance-abusing parolees.

    PubMed

    Prendergast, Michael; Frisman, Linda; Sacks, Joann Y; Staton-Tindall, Michele; Greenwell, Lisa; Lin, Hsiu-Ju; Cartier, Jerry

    2011-09-01

    OBJECTIVES: To test whether strengths-based case management provided during an inmate's transition from incarceration to the community increases participation in community substance abuse treatment, enhances access to needed social services, and improves drug use, crime, and HIV risk outcomes. METHODS: In a multi-site trial, inmates (men and women) in four states (n = 812) were randomly assigned (within site) to receive either Transitional Case Management (TCM group), based on strengths-based principles, or standard parole services (SR group). Data were collected at baseline and at 3 and 9 months following release from prison. Analyses compared the two groups with respect to services received and to drug use, crime, and HIV risk behavior outcomes. RESULTS: There were no significant differences between parolees in the TCM group and the SR group on outcomes related to participation in drug abuse treatment, receipt of social services, or drug use, crime, and HIV risk behaviors. For specific services (e.g., residential treatment, mental health), although significant differences were found for length of participation or for number of visits, the number of participants in these services was small and the direction of effect was not consistent. CONCLUSION: In contrast to positive findings in earlier studies of strengths-based case management with mental-health and drug-abuse clients, this study found that case management did not improve treatment participation or behavioral outcomes for parolees with drug problems. The discussion includes possible reasons for the findings and suggestions for modifications to the intervention that could be addressed in future research.

  10. Reliability of neuroanatomical measurements in a multi-site longitudinal study of youth at risk for psychosis

    PubMed Central

    Cannon, Tyrone D.; Sun, Frank; McEwen, Sarah Jacobson; Papademetris, Xenophon; He, George; van Erp, Theo G.M.; Jacobson, Aron; Bearden, Carrie E.; Walker, Elaine; Hu, Xiaoping; Zhou, Lei; Seidman, Larry J.; Thermenos, Heidi W.; Cornblatt, Barbara; Olvet, Doreen M.; Perkins, Diana; Belger, Aysenil; Cadenhead, Kristin; Tsuang, Ming; Mirzakhanian, Heline; Addington, Jean; Frayne, Richard; Woods, Scott W.; McGlashan, Thomas H.; Constable, R. Todd; Qiu, Maolin; Mathalon, Daniel H.; Thompson, Paul; Toga, Arthur W.

    2013-01-01

    Multi-site longitudinal neuroimaging designs are used to identify differential brain structural change associated with onset or progression of disease. The reliability of neuroanatomical measurements over time and across sites is a crucial aspect of power in such studies. Prior work has found that while within-site reliabilities of neuroanatomical measurements are excellent, between-site reliability is generally more modest. Factors that may increase between-site reliability include standardization of scanner platform and sequence parameters and correction for between-scanner variations in gradient nonlinearities. Factors that may improve both between- and within-site reliability include use of registration algorithms that account for individual differences in cortical patterning and shape. In this study 8 healthy volunteers were scanned twice on successive days at 8 sites participating in the North American Prodrome Longitudinal Study (NAPLS). All sites employed 3 Tesla scanners and standardized acquisition parameters. Site accounted for 2 to 30% of the total variance in neuroanatomical measurements. However, site-related variations were trivial (<1%) among sites using the same scanner model and 12-channel coil or when correcting for between-scanner differences in gradient nonlinearity and scaling. Adjusting for individual differences in sulcal-gyral geometries yielded measurements with greater reliabilities than those obtained using an automated approach. Neuroimaging can be performed across multiple sites at the same level of reliability as at a single site, achieving within- and between-site reliabilities of 0.95 or greater for gray matter density in the majority of voxels in the prefrontal and temporal cortical surfaces as well as for the volumes of most subcortical structures. PMID:23982962

  11. Multi-site thrombus imaging and fibrin content estimation with a single whole-body PET scan in rats

    PubMed Central

    Blasi, Francesco; Oliveira, Bruno L; Rietz, Tyson A.; Rotile, Nicholas J; Naha, Pratap C; Cormode, David P; Izquierdo-Garcia, David; Catana, Ciprian; Caravan, Peter

    2015-01-01

    Objective Thrombosis is a leading cause of morbidity and mortality worldwide. Current diagnostic strategies rely on imaging modalities that are specific for distinct vascular territories, but a thrombus-specific whole-body imaging approach is still missing. Moreover, imaging techniques to assess thrombus composition are underdeveloped, although therapeutic strategies may benefit from such technology. Therefore, our goal was to test whether positron emission tomography (PET) with the fibrin-binding probe 64Cu-FBP8 allows multi-site thrombus detection and fibrin content estimation. Approach and Results Thrombosis was induced in Sprague-Dawley rats (n=32) by ferric chloride application on both carotid artery and femoral vein. 64Cu-FBP8-PET/CT imaging was performed 1, 3 or 7 days after thrombosis to detect thrombus location and to evaluate age-dependent changes in target uptake. Ex vivo biodistribution, autoradiography and histopathology were performed to validate imaging results. Arterial and venous thrombi were localized on fused PET/CT images with high accuracy (97.6%, 95% confidence interval: 92–100%). A single whole-body PET/MR imaging session was sufficient to reveal the location of both arterial and venous thrombi after 64Cu-FBP8 administration. PET imaging showed that probe uptake was greater in younger clots than in older ones for both arterial and venous thrombosis (P<0.0001). Quantitative histopathology revealed an age-dependent reduction of thrombus fibrin content (P<0.001), consistent with PET results. Biodistribution and autoradiography further confirmed the imaging findings. Conclusions We demonstrated that 64Cu-FBP8-PET is a feasible approach for whole-body thrombus detection, and that molecular imaging of fibrin can provide, noninvasively, insight into clot composition. PMID:26272938

  12. Stimulant Abuser Groups to Engage in 12-Step (STAGE-12): A Multisite Trial in the NIDA Clinical Trials Network

    PubMed Central

    Donovan, Dennis M.; Daley, Dennis C.; Brigham, Gregory S.; Hodgkins, Candace C.; Perl, Harold I.; Garrett, Sharon; Doyle, Suzanne; Floyd, Anthony S.; Knox, Patricia C.; Botero, Christopher; Kelly, Thomas; Killeen, Therese; Hayes, Carole; Baumhofer, Nicole Kau’i; Seamans, Cindy; Zammarelli, Lucy

    2012-01-01

    Aims The study evaluated the effectiveness of an 8-week combined group plus individual 12-step facilitative intervention on stimulant drug use and 12-step meeting attendance and service. Design Multisite randomized controlled trial, with assessments at baseline, mid-treatment, end of treatment, and 3- and 6-month post-randomization follow-ups (FU). Setting Intensive outpatient substance treatment programs. Participants Individuals with stimulant use disorders (n = 471) randomly assigned to treatment as usual (TAU) or TAU into which the STAGE-12 intervention was integrated. Measurements Urinalysis and self-reports of substance use and 12-step attendance and activities. Intervention Group sessions focused on increasing acceptance of 12-step principles; individual sessions incorporated an intensive referral procedure connecting participants to 12-step volunteers. Findings Compared to TAU, STAGE-12 participants had significantly greater odds of self-reported stimulant abstinence during the active 8-week treatment phase; however, among those who had not achieved abstinence during this period, STAGE-12 participants had more days of use. STAGE-12 participants had lower ASI Drug Composite scores at and a significant reduction from baseline to the 3-month FU, attended 12-step meetings on a greater number of days during the early phase of active treatment, engaged in more other types of 12-step activities throughout the active treatment phase and the entire FU period, and had more days of self-reported service at meetings from mid-treatment through the 6-month FU. Conclusions The present findings are mixed with respect to the impact of integrating the STAGE-12 intervention into intensive outpatient drug treatment compared to TAU on stimulant drug use. However, the results more clearly indicate that individuals in STAGE-12 had higher rates of 12-step meeting attendance and were engaged in more related activities throughout both the active treatment phase and the entire 6

  13. Responsiveness of the Eating Disorders Quality of Life Scale (EDQLS) in a longitudinal multi-site sample

    PubMed Central

    2010-01-01

    Background In eating disorders (EDs), treatment outcome measurement has traditionally focused on symptom reduction rather than functioning or quality of life (QoL). The Eating Disorders Quality of Life Scale (EDQLS) was recently developed to allow for measurement of broader outcomes. We examined responsiveness of the EDQLS in a longitudinal multi-site study. Methods The EDQLS and comparator generic QoL scales were collected in person at baseline, and 3 and 6 months from 130 participants (mean age 25.6 years; range 14-60) in 12 treatment programs in four Canadian provinces. Total score differences across the time points and responsiveness were examined using both anchor- and distribution-based methods. Results 98 (75%) and 85 (65%) responses were received at 3 and 6 months respectively. No statistically significant differences were found between the baseline sample and those lost to follow-up on any measured characteristic. Mean EDQLS total scores increased from 110 (SD = 24) to 124.5 (SD = 29) at 3 months and 129 (SD = 28) at 6 months, and the difference by time was tested using a general linear model (GLM) to account for repeated measurement (p < .001). Responsiveness was good overall (Cohen's d = .61 and .80), and confirmed using anchor methods across 5 levels of self-reported improvement in health status (p < .001). Effect sizes across time were moderate or large for for all age groups. Internal consistency (Chronbach's alpha=.96) held across measurement points and patterns of responsiveness held across subscales. EDQLS responsiveness exceeded that of the Quality of Life Inventory, the Short Form-12 (mental and physical subscales) and was similar to the 16-dimension quality of life scale. Conclusions The EDQLS is responsive to change in geographically diverse and clinically heterogeneous programs over a relatively short time period in adolescents and adults. It shows promise as an outcome measure for both research and clinical practice. PMID:20701776

  14. Rater Training for a Multi-Site, International Clinical Trial: What Mood Symptoms may be most Difficult to Rate?

    PubMed Central

    Sajatovic, Martha; Gaur, Richa; Tatsuoka, Curtis; De Santi, Susan; Lee, Nathan; Laredo, Judith; Tripathi, Sulabh

    2011-01-01

    Aims Given resource constraints in conducting clinical trials, it is critical that rater training focuses on scale items wherein standardization is most challenging. This analysis examined mood disorder symptom ratings submitted in an online rater training program conducted preparatory to the initiation of a multi-site, international mood disorder treatment trial. Ratings were entered online and analyzed for consistency and variability, and compared to established standards (Gold Consensus Ratings/ GCRs). Methods Raters participated in web-based rater training on the Hamilton Depression Rating Scale (HAM-D), Montgomery Asberg Rating Scale (MADRS), and Young Mania Rating Scale (YMRS). Training included integration of didactic materials and videos of two bipolar depressed patients interviewed by two U.S. clinicians. Raters viewed the videos and rated the mood scales. Inter-rater agreement was assessed using Kappa statistics. Ratings between the raters and the GCRs for individual scale items were assessed using McNemar test for paired binomial proportions. Results 194 raters from 16 countries, 80 sites and speaking 20 different languages participated. Interrater agreement on videos ratings ranged from substantial to moderate (HAM-D, Kappa video A = 0.72, video B = 0.65, p < 0.001), (MADRS, Kappa = 0.65 and 0.47, p < 0.001), (YMRS, Kappa = 0.75, and 0.64, p < 0.001). There was no significant difference on agreement based upon on English proficiency, clinical experience, or by country. Scale items that differed from the GCR on the HAM-D were depressed mood, delayed insomnia, retardation, and anxiety (psychic). Items that differed on the MADRS were apparent sadness, inner tension, concentration difficulties, lassitude and inability to feel. Items that differed on the YMRS were irritability and disruptive behavior. Conclusions Identification of specific rating scale items in which rater variability is greatest may facilitate training approaches that target these areas for

  15. Vibrational spectroscopic evidence for (NO)3 formation on Cu(111)

    NASA Astrophysics Data System (ADS)

    Koshida, H.; Okuyama, H.; Hatta, S.; Aruga, T.

    2016-08-01

    The formation of (NO)3 on Cu(111) was recently reported based on scanning tunneling microscopy observations [A. Shiotari et al., J. Chem. Phys. 141, 134705 (2014)]. We herein report studies into this system using electron energy loss spectroscopy and verify the above findings through vibrational analysis. For the surface covered with mixed isotopes of N16O and N18O, we observed four peaks corresponding to N-O stretching vibrations, which were ascribed to the four isotopic combinations of the trimer. Dynamic coupling within the trimer was evaluated from model calculations of the coupled oscillators. Furthermore, we observed hindered rotation and translation modes in the dipole scattering regime, suggesting that the molecular axis is tilted from the surface normal. These results provide spectroscopic support for the formation of (NO)3 on Cu(111).

  16. Spectroscopic properties of nuclear skyrme energy density functionals.

    PubMed

    Tarpanov, D; Dobaczewski, J; Toivanen, J; Carlsson, B G

    2014-12-19

    We address the question of how to improve the agreement between theoretical nuclear single-particle energies (SPEs) and observations. Empirically, in doubly magic nuclei, the SPEs can be deduced from spectroscopic properties of odd nuclei that have one more or one less neutron or proton. Theoretically, bare SPEs, before being confronted with observations, must be corrected for the effects of the particle vibration coupling (PVC). In the present work, we determine the PVC corrections in a fully self-consistent way. Then, we adjust the SPEs, with PVC corrections included, to empirical data. In this way, the agreement with observations, on average, improves; nevertheless, large discrepancies still remain. We conclude that the main source of disagreement is still in the underlying mean fields, and not in including or neglecting the PVC corrections.

  17. Vibrational spectroscopic evidence for (NO)3 formation on Cu(111).

    PubMed

    Koshida, H; Okuyama, H; Hatta, S; Aruga, T

    2016-08-01

    The formation of (NO)3 on Cu(111) was recently reported based on scanning tunneling microscopy observations [A. Shiotari et al., J. Chem. Phys. 141, 134705 (2014)]. We herein report studies into this system using electron energy loss spectroscopy and verify the above findings through vibrational analysis. For the surface covered with mixed isotopes of N(16)O and N(18)O, we observed four peaks corresponding to N-O stretching vibrations, which were ascribed to the four isotopic combinations of the trimer. Dynamic coupling within the trimer was evaluated from model calculations of the coupled oscillators. Furthermore, we observed hindered rotation and translation modes in the dipole scattering regime, suggesting that the molecular axis is tilted from the surface normal. These results provide spectroscopic support for the formation of (NO)3 on Cu(111). PMID:27497570

  18. Multi-site tumor sampling (MSTS) improves the performance of histological detection of intratumor heterogeneity in clear cell renal cell carcinoma (CCRCC).

    PubMed

    Guarch, Rosa; Cortés, Jesús M; Lawrie, Charles H; López, José I

    2016-01-01

    Current standard-of-care tumor sampling protocols for CCRCC (and other cancers) are not efficient at detecting intratumoural heterogeneity (ITH). We have demonstrated in silico that an alternative protocol, multi-site tumor sampling (MSTS) based upon the divide and conquer (DAC) algorithm, can significantly increase the efficiency of ITH detection without extra costs. Now we test this protocol on routine hematoxylin-eosin (HE) sections in a series of 38 CCRCC cases. MSTS was found to outperform traditional sampling when detecting either high grade (p=0.0136) or granular/eosinophilic cells (p=0.0114). We therefore propose that MSTS should be used in routine clinical practice. PMID:27635226

  19. Multi-site tumor sampling (MSTS) improves the performance of histological detection of intratumor heterogeneity in clear cell renal cell carcinoma (CCRCC)

    PubMed Central

    Guarch, Rosa; Cortés, Jesús M.

    2016-01-01

    Current standard-of-care tumor sampling protocols for CCRCC (and other cancers) are not efficient at detecting intratumoural heterogeneity (ITH). We have demonstrated in silico that an alternative protocol, multi-site tumor sampling (MSTS) based upon the divide and conquer (DAC) algorithm, can significantly increase the efficiency of ITH detection without extra costs. Now we test this protocol on routine hematoxylin-eosin (HE) sections in a series of 38 CCRCC cases. MSTS was found to outperform traditional sampling when detecting either high grade (p=0.0136) or granular/eosinophilic cells (p=0.0114). We therefore propose that MSTS should be used in routine clinical practice. PMID:27635226

  20. Research Partnerships between Academic Institutions and American Indian and Alaska Native Tribes and Organizations: Effective Strategies and Lessons Learned in a Multi-Site CTN Study

    PubMed Central

    Thomas, Lisa Rey; Rosa, Carmen; Forcehimes, Alyssa; Donovan, Dennis M.

    2012-01-01

    Community Based and Tribally Based Participatory Research (CBPR/TPR) are approaches that can be successful for developing ethical and effective research partnerships between academic institutions and Tribes and Native organizations. The NIDA Clinical Trials Network funded a multi-site, exploratory study using CBPR/TPR to begin to better understand substance abuse issues of concern to some Tribes and Native organizations as well as strengths and resources that exist in these communities to address these concerns. Each of the five sites is briefly described and a summary of the common themes for developing these collaborative research efforts is provided. PMID:21854275