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Sample records for mussinan editor michael

  1. An interview with Lucio G. Costa and Michael Aschner, section editors for toxicology.

    PubMed

    Costa, Lucio G; Aschner, Michael

    2012-11-15

    Lucio G. Costa is currently Professor of Environmental and Occupational Health Sciences at the School of Public Health at the University of Washington. Dr. Costa is a renowned neurotoxicologist whose research interests are focused on understanding the role of neurotoxic substances in neurodevelopmental disorders and other neurological, neuropsychiatric and neurodegenerative diseases. Dr Costa's research laboratory makes use of a variety of in vivo and in vitro cell culture systems, transgenic animal models and imaging techniques to study the cellular, biochemical and molecular mechanisms of neurotoxicity.Michael Aschner is the Gray E. B. Stahlman Professor of Pediatrics and Pharmacology at Vanderbilt University School of Medicine as well as a Senior Investigator at the Kennedy Center for Research on Human Development. Dr Aschner's research group has a particular interest in the neurobiology and physiology of astrocytes and the signaling mechanisms associated with central nervous system injury. Dr Aschner's laboratory studies metal uptake and distribution in the brain, investigating the mechanisms of transport of methylmercury and manganese across the capillaries of the blood-brain barrier. His research utilizes various experimental models (C. elegans, tissue cultures and rodents) to understand the acute toxicity of manganese deposition in the brains of human neonates.In this interview we find out a little more about the key issues in the field of toxicology research.

  2. Michael Polanyi 1891-1976: A Rememberance

    ERIC Educational Resources Information Center

    Manno, Bruno V.

    1977-01-01

    Michael Polanyi was on "JHP's" Board of Editors for many years, and his book, "Personal Knowledge", published in 1958, was an important factor in the development of humanistic psychology. This "rememberance" presents an overview of his personal background and the major outlines of his thought. (Editor/RK)

  3. New Editor

    NASA Astrophysics Data System (ADS)

    2007-03-01

    It is an honour and a challenge to take up the editorship of the Messenger at this time of ESO's expanding role in European and worldwide astronomy. In order to mark the change, we have made a few adjustments to the appearance without departing from the overall style that Peter Shaver had evolved during his term as editor. I would like to thank Peter for gen-tly coaching me into the position and Jutta Boxheimer, the technical editor, for the high quality of the layout.

  4. TOAD Editor

    NASA Technical Reports Server (NTRS)

    Bingle, Bradford D.; Shea, Anne L.; Hofler, Alicia S.

    1993-01-01

    Transferable Output ASCII Data (TOAD) computer program (LAR-13755), implements format designed to facilitate transfer of data across communication networks and dissimilar host computer systems. Any data file conforming to TOAD format standard called TOAD file. TOAD Editor is interactive software tool for manipulating contents of TOAD files. Commonly used to extract filtered subsets of data for visualization of results of computation. Also offers such user-oriented features as on-line help, clear English error messages, startup file, macroinstructions defined by user, command history, user variables, UNDO features, and full complement of mathematical statistical, and conversion functions. Companion program, TOAD Gateway (LAR-14484), converts data files from variety of other file formats to that of TOAD. TOAD Editor written in FORTRAN 77.

  5. MPS Editor

    NASA Technical Reports Server (NTRS)

    Mathews, William S.; Liu, Ning; Francis, Laurie K.; OReilly, Taifun L.; Schrock, Mitchell; Page, Dennis N.; Morris, John R.; Joswig, Joseph C.; Crockett, Thomas M.; Shams, Khawaja S.

    2011-01-01

    Previously, it was time-consuming to hand-edit data and then set up simulation runs to find the effect and impact of the input data on a spacecraft. MPS Editor provides the user the capability to create/edit/update models and sequences, and immediately try them out using what appears to the user as one piece of software. MPS Editor provides an integrated sequencing environment for users. It provides them with software that can be utilized during development as well as actual operations. In addition, it provides them with a single, consistent, user friendly interface. MPS Editor uses the Eclipse Rich Client Platform to provide an environment that can be tailored to specific missions. It provides the capability to create and edit, and includes an Activity Dictionary to build the simulation spacecraft models, build and edit sequences of commands, and model the effects of those commands on the spacecraft. MPS Editor is written in Java using the Eclipse Rich Client Platform. It is currently built with four perspectives: the Activity Dictionary Perspective, the Project Adaptation Perspective, the Sequence Building Perspective, and the Sequence Modeling Perspective. Each perspective performs a given task. If a mission doesn't require that task, the unneeded perspective is not added to that project's delivery. In the Activity Dictionary Perspective, the user builds the project-specific activities, observations, calibrations, etc. Typically, this is used during the development phases of the mission, although it can be used later to make changes and updates to the Project Activity Dictionary. In the Adaptation Perspective, the user creates the spacecraft models such as power, data store, etc. Again, this is typically used during development, but will be used to update or add models of the spacecraft. The Sequence Building Perspective allows the user to create a sequence of activities or commands that go to the spacecraft. It provides a simulation of the activities and

  6. Journal Editors Celebrated at Editors' Evening

    NASA Astrophysics Data System (ADS)

    Panning, Jeanette

    2014-02-01

    At the Fall Meeting, the premiere social event for AGU's many journal editors is the annual Editors' Evening, an opportunity for members to celebrate and to recognize the efforts of retiring editors. At the event, AGU president Carol Finn welcomed all those in attendance and thanked them for volunteering their time for the benefit of AGU and the wider research community.

  7. Michael Polanyi: The University and the Technological State.

    ERIC Educational Resources Information Center

    Price, G. L.

    1978-01-01

    The problem of the intellectual independence of the university within a technologically oriented society was one of the problems which motivated Michael Polanyi's inquiry into the foundations of knowledge. The key elements of his resultant attempt to supersede objectivist accounts of science are isolated, and evaluated. (Editor/RK)

  8. Interview with Michael S. Dukakis. Interview by Richard Sorian.

    PubMed

    Dukakis, M S

    1992-01-01

    In early 1991, former Massachusetts Gov. Michael Dukakis spent three months at the University of Hawaii School of Public Health studying the state's unique system of health insurance. Recently he talked with JAHP Editor in Chief Richard Sorian about the lessons he learned from looking at Hawaii's "universal health coverage" and why the experience was different in his home state. PMID:10116476

  9. DNAAlignEditor: DNA alignment editor tool

    PubMed Central

    Sanchez-Villeda, Hector; Schroeder, Steven; Flint-Garcia, Sherry; Guill, Katherine E; Yamasaki, Masanori; McMullen, Michael D

    2008-01-01

    Background With advances in DNA re-sequencing methods and Next-Generation parallel sequencing approaches, there has been a large increase in genomic efforts to define and analyze the sequence variability present among individuals within a species. For very polymorphic species such as maize, this has lead to a need for intuitive, user-friendly software that aids the biologist, often with naïve programming capability, in tracking, editing, displaying, and exporting multiple individual sequence alignments. To fill this need we have developed a novel DNA alignment editor. Results We have generated a nucleotide sequence alignment editor (DNAAlignEditor) that provides an intuitive, user-friendly interface for manual editing of multiple sequence alignments with functions for input, editing, and output of sequence alignments. The color-coding of nucleotide identity and the display of associated quality score aids in the manual alignment editing process. DNAAlignEditor works as a client/server tool having two main components: a relational database that collects the processed alignments and a user interface connected to database through universal data access connectivity drivers. DNAAlignEditor can be used either as a stand-alone application or as a network application with multiple users concurrently connected. Conclusion We anticipate that this software will be of general interest to biologists and population genetics in editing DNA sequence alignments and analyzing natural sequence variation regardless of species, and will be particularly useful for manual alignment editing of sequences in species with high levels of polymorphism. PMID:18366684

  10. Following Michael Faraday's Footprints

    NASA Astrophysics Data System (ADS)

    Galeano, Javier

    2011-01-01

    Last fall I had the good fortune of receiving financial support to shoot a documentary about Michael Faraday. I took the opportunity to learn more about this great experimentalist and to visit the highlights of places in his life. In this paper, I would like to share a list and description of some of the most remarkable places in London suitable for following Michael Faraday's footprints. There are many other places in Europe of special interest for the physics teacher,2,3 and some useful guides to help us visit places as "scientific travelers,"4,5 but this paper focuses on Michael Faraday and London. I have personally visited most of the places described below and found the experience to be really worthwhile.

  11. From the Incoming Editors.

    ERIC Educational Resources Information Center

    Reed, W. Michael; Ayersman, David J.

    1999-01-01

    This note from the new editors of the "Journal of Research on Computing in Education" (JRCE) outlines their plans for JRCE during the next three years. Discussion includes the following: review board and associate editors, book reviews, early review, format templates on the JRCE Web site, and special topics and thematic issues. (AEF)

  12. Goodbye Michael Gove

    ERIC Educational Resources Information Center

    Bassey, Michael

    2014-01-01

    Michael Gove was Secretary of State for Education from May 2010 to July 2014 when the Prime Minister sacked him. With strong opinions arising from his own life experiences and outstanding energy for reform, but severely limited understanding of education and a refusal to consult teachers and other professionals, he imposed half-baked ideas on the…

  13. Following Michael Faraday's Footprints

    ERIC Educational Resources Information Center

    Galeano, Javier

    2011-01-01

    Last fall I had the good fortune of receiving financial support to shoot a documentary about Michael Faraday. I took the opportunity to learn more about this great experimentalist and to visit the highlights of places in his life. In this paper, I would like to share a list and description of some of the most remarkable places in London suitable…

  14. Michael Faraday's Bicentenary.

    ERIC Educational Resources Information Center

    Williams, L. Pearce; And Others

    1991-01-01

    Six articles discuss the work of Michael Faraday, a chemist whose work revolutionized physics and led directly to both classical field and relativity theory. The scientist as a young man, the electromagnetic experiments of Faraday, his search for the gravelectric effect, his work on optical glass, his laboratory notebooks, and his creative use of…

  15. EDITORIAL: Message from the Editor Message from the Editor

    NASA Astrophysics Data System (ADS)

    Thomas, Paul

    2010-02-01

    award was Steven A. Sabbagh et al for the paper entitled 'Resistive wall stabilized operation in rotating high beta NSTX plasmas' (Nucl. Fusion 46 635-644). Reviews Last year I announced a revival of Nuclear Fusion Reviews, following a decision by the Board of Editors. 'A review of zonal flow experiments', by Akihide Fujisawa was the first fruit of this. In 2010, we are expecting to publish further review articles, the first of which is entitled 'Gyrokinetic simulations of turbulent transport' by Xavier Garbet, Yasuhiro Idomura, Laurent Villard and Tomo-Hiko Watanabe. Letters At the 2009 Board of Editors Meeting in Atlanta, the current letters procedure was summarized and it was noted that the peer review time for Letters is quite variable. Some are accepted within a month of submission, others take longer. Since the purpose of Letters is to provide a route for rapid communication, this is quite an important matter. It was agreed that the Board of Editors would play a more active role in the Letter approval process. If a reviewer asks for a second revision the Editor or a Board of Editors member will be queried as to whether the submission should still be treated as a Letter rather than a regular Paper. The Board of Editors The following Board of Editors members reached the end of their term in 2009: Amanda Hubbard, Yaroslav Kolesnichenko, Kunioki Mima, Boris Sharkov and Michael Ulrickson. On behalf of the Nuclear Fusion Office and the Chairman of the Board of Editors, Mitsuru Kikuchi, I would like to thank them for their efforts in support of the journal. At the same time, we welcomed: Hiroshi Azechi, Xuru Duan, Richard Hawryluk, Sergey Konovalov, Bruce Lipschultz, Peter Norreys, Francesco Romanelli, Tony Taylor and Hartmut Zohm. I am sure that such an illustrious group does not need any introduction to the readers of Nuclear Fusion and I am confident that the new members can only further the success of the journal. It is with great sadness that I have to note the

  16. Michael Faraday, media man.

    PubMed

    Fara, Patricia

    2006-03-01

    Michael Faraday was an enthusiastic portrait collector, and he welcomed the invention of photography not only as a possible means of recording observations accurately, but also as a method for advertising science and its practitioners. This article (which is part of the Science in the Industrial Revolution series) shows that like many eminent scientists, Faraday took advantage of the burgeoning Victorian media industry by posing in various roles. PMID:16332391

  17. Michael Faraday, media man.

    PubMed

    Fara, Patricia

    2006-03-01

    Michael Faraday was an enthusiastic portrait collector, and he welcomed the invention of photography not only as a possible means of recording observations accurately, but also as a method for advertising science and its practitioners. This article (which is part of the Science in the Industrial Revolution series) shows that like many eminent scientists, Faraday took advantage of the burgeoning Victorian media industry by posing in various roles.

  18. Blog life: Michael Nielsen

    NASA Astrophysics Data System (ADS)

    Nielsen, Michael

    2008-08-01

    Who is the blog written by? Michael Nielsen is a theoretical physicist who, up until June, was based at the Perimeter Institute for Theoretical Physics in Waterloo, Canada. He is a pioneer of quantum computation, contributing significantly to the theory of entangled quantum states. Last year, however, he announced a major change in the focus of his research, which now centres on the development of new tools for scientific publication and collaboration.

  19. Editors' Fall Picks

    ERIC Educational Resources Information Center

    Hoffert, Barbara; Heilbrun, Margaret; Kuzyk, Raya; Kim, Ann; McCormack, Heather; Katterjohn, Anna; Burns, Ann; Williams, Wilda

    2008-01-01

    From the fall's cascade of great new books, "Library Journal's" editors select their favorites--a dark rendition of Afghan life, a look at the "self-esteem trap," a celebration of Brooklyn activism, and much more.

  20. ISTP CDF Skeleton Editor

    NASA Technical Reports Server (NTRS)

    Chimiak, Reine; Harris, Bernard; Williams, Phillip

    2013-01-01

    Basic Common Data Format (CDF) tools (e.g., cdfedit) provide no specific support for creating International Solar-Terrestrial Physics/Space Physics Data Facility (ISTP/SPDF) standard files. While it is possible for someone who is familiar with the ISTP/SPDF metadata guidelines to create compliant files using just the basic tools, the process is error-prone and unreasonable for someone without ISTP/SPDF expertise. The key problem is the lack of a tool with specific support for creating files that comply with the ISTP/SPDF guidelines. There are basic CDF tools such as cdfedit and skeletoncdf for creating CDF files, but these have no specific support for creating ISTP/ SPDF compliant files. The SPDF ISTP CDF skeleton editor is a cross-platform, Java-based GUI editor program that allows someone with only a basic understanding of the ISTP/SPDF guidelines to easily create compliant files. The editor is a simple graphical user interface (GUI) application for creating and editing ISTP/SPDF guideline-compliant skeleton CDF files. The SPDF ISTP CDF skeleton editor consists of the following components: A swing-based Java GUI program, JavaHelp-based manual/ tutorial, Image/Icon files, and HTML Web page for distribution. The editor is available as a traditional Java desktop application as well as a Java Network Launching Protocol (JNLP) application. Once started, it functions like a typical Java GUI file editor application for creating/editing application-unique files.

  1. GUEST EDITORS' INTRODUCTION: Guest Editors' introduction

    NASA Astrophysics Data System (ADS)

    Coulson, Geoff; de Meer, Jan B.

    1997-03-01

    service management' by Gregor v Bochmann and Abdelhakim Hafid offers lessons in QoS management learned during the implementation of a prototype News-on-Demand application. Some general principles are extracted from this experience. In particular, a novel QoS adaptation technique is highlighted: transparent automatic reconfiguration of the components involved in a communication (e.g. choice of an alternative network or server at run time). An algorithm which attempts to choose optimal configurations is discussed. `Quality of service management using generic modelling and monitoring techniques', by Leonard Franken and Boudewijn Haverkort investigates the use of Petri nets as the basis of generic QoS monitoring of distributed applications. A distributed application is exploded into finegrained component parts and interactions between these parts are instrumented. The paper offers a case study of the instrumentation of a videophone application using this technique. Simulation is used to evaluate the scheme. The final two papers in the special issue are more focused and pragmatic in nature. These papers explore QoS provision in particular environments (the World Wide Web and ATM networks respectively) through reported implementation experience. `QoS management in a World Wide Web environment which supports continuous media' by Michael Fry, Aruna Seneviratne, Andreas Vogel and Varuni Witana looks at the practical provision of end to end QoS management in the World Wide Web. The paper looks beyond currently available tools such as RealAudio and StreamWorks and presents a QoS managed RTP based solution featuring an adjunct QoS management protocol. This work offers QoS management functions (e.g. QoS negotiation, adaptation and control of QoS degradation paths) directly to the user via the usual Web GUI. `A QoS adaptive multimedia transport system: design, implementation and experiences' by Andrew Campbell and Geoff Coulson offers further practical experience of QoS management

  2. Enantioselective Michael Addition of Water

    PubMed Central

    Chen, Bi-Shuang; Resch, Verena; Otten, Linda G; Hanefeld, Ulf

    2015-01-01

    The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus strains is described. Good yields and excellent enantioselectivities were achieved with this method. Deuterium labeling studies demonstrate that a Michael hydratase catalyzes the water addition exclusively with anti-stereochemistry. PMID:25529526

  3. Enantioselective Michael addition of water.

    PubMed

    Chen, Bi-Shuang; Resch, Verena; Otten, Linda G; Hanefeld, Ulf

    2015-02-01

    The enantioselective Michael addition using water as both nucleophile and solvent has to date proved beyond the ability of synthetic chemists. Herein, the direct, enantioselective Michael addition of water in water to prepare important β-hydroxy carbonyl compounds using whole cells of Rhodococcus strains is described. Good yields and excellent enantioselectivities were achieved with this method. Deuterium labeling studies demonstrate that a Michael hydratase catalyzes the water addition exclusively with anti-stereochemistry.

  4. A century of editors.

    PubMed

    Riley, R W

    1983-07-01

    They are unalike and far apart, these 13 past editors of The Journal. Between Nathan S. Davis's first issue and William R. Barclay's retirement, there was almost a century of change in medicine, society, the American Medical Association, prose style, and editorial needs. During these years, the editors ranged from the brilliant organizers John B. Hamilton and George H. Simmons to the diligent John H. Hollister and the devoted Johnson F. Hammond. There were editors with the hot determination of James C. Culbertson, John H. Talbott, and Robert H. Moser, and there were those with the cool precision of Austin Smith and Hugh H. Hussey. They varied from Morris Fishbein, who wrote and spoke "with the grade of an eagle in its unhindered soar," to Truman W. Miller, who wrote scarcely a word. Here, briefly, they are together.

  5. PANEL LIBRARY AND EDITOR

    NASA Technical Reports Server (NTRS)

    Raible, E.

    1994-01-01

    The Panel Library and Editor is a graphical user interface (GUI) builder for the Silicon Graphics IRIS workstation family. The toolkit creates "widgets" which can be manipulated by the user. Its appearance is similar to that of the X-Windows System. The Panel Library is written in C and is used by programmers writing user-friendly mouse-driven applications for the IRIS. GUIs built using the Panel Library consist of "actuators" and "panels." Actuators are buttons, dials, sliders, or other mouse-driven symbols. Panels are groups of actuators that occupy separate windows on the IRIS workstation. The application user can alter variables in the graphics program, or fire off functions with a click on a button. The evolution of data values can be tracked with meters and strip charts, and dialog boxes with text processing can be built. Panels can be stored as icons when not in use. The Panel Editor is a program used to interactively create and test panel library interfaces in a simple and efficient way. The Panel Editor itself uses a panel library interface, so all actions are mouse driven. Extensive context-sensitive on-line help is provided. Programmers can graphically create and test the user interface without writing a single line of code. Once an interface is judged satisfactory, the Panel Editor will dump it out as a file of C code that can be used in an application. The Panel Library (v9.8) and Editor (v1.1) are written in C-Language (63%) and Scheme, a dialect of LISP, (37%) for Silicon Graphics 4D series workstations running IRIX 3.2 or higher. Approximately 10Mb of disk space is required once compiled. 1.5Mb of main memory is required to execute the panel editor. This program is available on a .25 inch streaming magnetic tape cartridge in UNIX tar format for an IRIS, and includes a copy of XScheme, the public-domain Scheme interpreter used by the Panel Editor. The Panel Library Programmer's Manual is included on the distribution media. The Panel Library and

  6. Editors' Spring Picks

    ERIC Educational Resources Information Center

    Library Journal, 2011

    2011-01-01

    While they do not represent the rainbow of reading tastes American public libraries accommodate, Book Review editors are a wildly eclectic bunch. One look at their bedside tables and ereaders would reveal very little crossover. This article highlights an eclectic array of spring offerings ranging from print books to an audiobook to ebook apps. It…

  7. LDAP Browser/Editor

    SciTech Connect

    Gawor, Jarek; Laszewski, Gregor von

    2000-07-18

    The LDAP Browser/Editor provides a user-friendly Java-based interface to LDAP databases with tightly integrated browsing and editing capabilities. Entirely written in Java with help of the JFC (Swingset) and JNDI class libraries. It connects to any X.500, LDAP v2 and v3 servers and supports editing of multiple-value attributes.

  8. WRR editor Ronald Cummings

    NASA Astrophysics Data System (ADS)

    1984-04-01

    It has been nearly a year since Ronald Cummings took over as policy sciences editor of Water Resources Research (WRR), and in that time he has worked to make the journal live up to its role as “an interdisciplinary journal integrating research in the social and natural sciences of water.” Cummings takes the “interdisciplinary” part seriously. “I'd like to see a much broader range of policy issues presented to readers,” he says. “I would hope it would then stimulate interchange between our colleagues concerning evolving issues of the '80s and '90s.”Cummings brings a solid background as a resource economist to his 4-year term as editor, which began last January and runs until December 1987. Cummings succeeds Jared Cohon as policy sciences editor. Stephen J. Burges is the WRR editor for hydrological, physical, chemical, and biological sciences. Now a Professor of Economics and Director of the Program in Natural Resources Economics at the University of New Mexico, Cummings is a past president of the Association of Environmental and Resource Economists. He has been a consultant in matters of water resources management, forestry management, and energy policy for more than a decade, working on projects in both the United States and Latin America. Since joining the faculty at New Mexico in 1975, he has, among other things, worked with engineers at the Los Alamos National Laboratory in developing operation'management models for hot, dry rock geothermal systems.

  9. Editors' Fall Picks

    ERIC Educational Resources Information Center

    Heilbrun, Margaret; McCormack, Heather; Katterjohn, Anna; Kuzyk, Raya; Roncevic, Mirela; Fox, Bette-Lee; Hoffert, Barbara

    2009-01-01

    "Library Journal's" review editors select fall titles readers won't want to miss--"Waiting on a Train: The Embattled Future of Passenger Rail Service" (James McCommons); "Happy" (Alex Lemon); "Free for All: Joe Papp, the Public, and the Greatest Theater Story Ever Told" (Kenneth Turan & Joseph Papp); "In My Father's Shadow: A Daughter Remembers…

  10. Meet the APS Journal Editors

    NASA Astrophysics Data System (ADS)

    2016-05-01

    The Editors of the APS journals invite you to join them for conversation. The Editors will be available to answer questions, hear your ideas, and discuss any comments about the journals. All are welcome. Light refreshments will be served.

  11. The Solid Gold Copy Editor.

    ERIC Educational Resources Information Center

    Riblet, Carl, Jr.

    This book discusses the role of the newspaper copy editor on a daily newspaper and contains lessons instructing editors on how to prepare copy for print. The book is specifically designed to polish the skills of the already experienced newspaper copy editor, although a beginner will find the lessons useful and instructive. Contained in the lessons…

  12. Letters to the Editor

    NASA Astrophysics Data System (ADS)

    2000-11-01

    All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents The equivalence of mass and energy Peter Stansbury Head of Physics, Christ Church Grammar School, Claremont, Western Australia 6010 Comment on `A simple experiment to study parabolic surfaces' N Gauthier Department of Physics, The Royal Military College of Canada, Kingston, Ontario K7K 7B4, Canada

  13. Letters to the Editor

    NASA Astrophysics Data System (ADS)

    1997-03-01

    All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Criticisms of hands-on pseudoscience David J Fisher 27 Elderberry Road, Cardiff CF5 3RG, UK Measuring varying fields Don Koks Adelaide University, Australia Relativity at A-level: a comment David Sang 3 Ellasdale Road, Bognor Regis, PO21 2SG, UK

  14. ION Configuration Editor

    NASA Technical Reports Server (NTRS)

    Borgen, Richard L.

    2013-01-01

    The configuration of ION (Inter - planetary Overlay Network) network nodes is a manual task that is complex, time-consuming, and error-prone. This program seeks to accelerate this job and produce reliable configurations. The ION Configuration Editor is a model-based smart editor based on Eclipse Modeling Framework technology. An ION network designer uses this Eclipse-based GUI to construct a data model of the complete target network and then generate configurations. The data model is captured in an XML file. Intrinsic editor features aid in achieving model correctness, such as field fill-in, type-checking, lists of valid values, and suitable default values. Additionally, an explicit "validation" feature executes custom rules to catch more subtle model errors. A "survey" feature provides a set of reports providing an overview of the entire network, enabling a quick assessment of the model s completeness and correctness. The "configuration" feature produces the main final result, a complete set of ION configuration files (eight distinct file types) for each ION node in the network.

  15. Interview with Michael Gazzaniga.

    PubMed

    Gazzaniga, Michael

    2011-04-01

    Widely considered the father of the field of cognitive neuroscience, Professor Michael S. Gazzaniga is one of the world's premier neuroscientists. He founded the Center for Neuroscience at the University of California, Davis; the Center for Cognitive Neuroscience at Dartmouth College; the Cognitive Neuroscience Institute; Journal of Cognitive Neuroscience; and the Cognitive Neuroscience Society. He is currently the director of the Sage Center for the Study of the Mind at the University of California, Santa Barbara. Born on December 12, 1939 in Los Angeles and educated at Dartmouth College, he received his Ph.D. in psychobiology at the California Institute of Technology under the tutelage of Roger Sperry. As a graduate student, Professor Gazzaniga initiated the first lateralized testing of human split-brain patients, leading to a fundamental shift in our understanding of functional lateralization in the brain and how the cerebral hemispheres communicate with one another. His many scholarly publications and pioneering work during the last 50 years have produced significant contributions to our understanding of how the brain enables the mind. His landmark 1995 book for MIT Press, The Cognitive Neurosciences, now in its fourth edition, is recognized as the sourcebook for the field. He has also published many books accessible to a lay audience, including Mind Matters, Nature's Mind, and The Ethical Brain. PMID:21486292

  16. Interview with Michael Gazzaniga.

    PubMed

    Gazzaniga, Michael

    2011-04-01

    Widely considered the father of the field of cognitive neuroscience, Professor Michael S. Gazzaniga is one of the world's premier neuroscientists. He founded the Center for Neuroscience at the University of California, Davis; the Center for Cognitive Neuroscience at Dartmouth College; the Cognitive Neuroscience Institute; Journal of Cognitive Neuroscience; and the Cognitive Neuroscience Society. He is currently the director of the Sage Center for the Study of the Mind at the University of California, Santa Barbara. Born on December 12, 1939 in Los Angeles and educated at Dartmouth College, he received his Ph.D. in psychobiology at the California Institute of Technology under the tutelage of Roger Sperry. As a graduate student, Professor Gazzaniga initiated the first lateralized testing of human split-brain patients, leading to a fundamental shift in our understanding of functional lateralization in the brain and how the cerebral hemispheres communicate with one another. His many scholarly publications and pioneering work during the last 50 years have produced significant contributions to our understanding of how the brain enables the mind. His landmark 1995 book for MIT Press, The Cognitive Neurosciences, now in its fourth edition, is recognized as the sourcebook for the field. He has also published many books accessible to a lay audience, including Mind Matters, Nature's Mind, and The Ethical Brain.

  17. EDITORIAL: Editor's Farewell

    NASA Astrophysics Data System (ADS)

    Hudson, R. P.

    1989-01-01

    The completion of Volume 26, 1989, marked the end of my tenure as Editor of Metrologia. My association with the journal, its parent body the Comité International des Poids et Mesures, its host organization the Bureau International des Poids et Mesures, the publishers Springer-Verlag and last (but by no means least) the Editorial Board, has been a pleasant one and I trust that the subscribers will have found the product to be generally satisfactory. There have been, it is true, some disappointments along the way and I shall mention two of these while expressing the hope that the new Editor will enjoy a greater success in their regard. First is the question of circulation, which has stayed dangerously low, although the shrinkage has tapered off in the most recent years. Because of the narrow public support, the costs of production are relatively high and this, through a consequently high subscription rate, tends to enshrine the unsatisfactory state of affairs. Modest schemes to broaden the journal's appeal and bring in a wider readership have foundered upon the first step, namely, that of procuring from staff members of the national standards laboratories the hoped-for articles which would discuss the state of the art in delivering the highest-quality measurement services to the public. However, some very interesting and bolder schemes are presently under discussion. I had also hoped to leaven the journal's content a little by regularly appearing articles on the latest developments within the great national laboratories. But, as with technical review articles, it has proven very difficult to find the right authors who can also spare the time, and only a few laboratories have found it possible to collaborate. In taking my leave, it remains for me to thank all the contributors, referees and readers for their support, to express the hope of an ever brighter future for Metrologia and to wish to the new Editor, Dr D A Blackburn, a happy and successful tenure.

  18. Letters to the Editor

    NASA Astrophysics Data System (ADS)

    1997-01-01

    All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Software teaching of modular physics: SToMP Stephen Hearn Head of Science, Charterhouse, Godalming, Surrey GU7 2DX Bridging the gap or avoiding a chasm? R W West York Strengths and weaknesses of science John Bausor Christians in Science Education, Edgware, London HA8 6RR Addressing the issues Philip Britton Head of Physics, Leeds Grammar School Modern syllabuses and old textbooks: a useful synthesis Richard Barrass St Mary's College, Doncaster DN1 2ES

  19. The Meta Sketch Editor

    NASA Astrophysics Data System (ADS)

    Nóbrega, Leonel; Nunes, Nuno Jardim; Coelho, Helder

    The Model Driven Development has its foundations on metamodeling and new tools are required in order to support users on the definition and customization of their modeling languages. The MetaSketch Editor takes advantage of the current OMG technology to provide the metamodeling mechanisms required to support the integration of some widely used human-computer interaction (HCI) notation into the UML, through precise and semantically sound metamodeling extensions. With this integration, HCI field could contribute to leverage the model-driven development paradigm and support automatic generation of interactive applications

  20. Letters to the Editor

    NASA Astrophysics Data System (ADS)

    1998-03-01

    All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Comment on `Magnetic and electric field strengths of high voltage power lines and household appliances' José Luis Giordano Dept. de Ciencia y Tecnología de Materiales y Fluidos, CPSI, Universidad de Zaragoza, Spain Twins paradox S R Carson Norton College, Malton, North Yorkshire, UK On alternative ways of finding the ratio of specific heats of gases Tomas Ficker Physics Department, Technical University of Brno, Czech Republic

  1. Microbial Properties Database Editor Tutorial

    EPA Science Inventory

    A Microbial Properties Database Editor (MPDBE) has been developed to help consolidate microbial-relevant data to populate a microbial database and support a database editor by which an authorized user can modify physico-microbial properties related to microbial indicators and pat...

  2. Editors in the Electronic Age.

    ERIC Educational Resources Information Center

    Dye, Robert M., Ed.

    Intended for newspaper writers and editors, this collection of articles includes the following titles and authors: "VDTs, TV Haven't Shocked Editors" by Jay Rogers; "Opinions Vary on Electronics' Effect" by Bob Nordyke; "A Few Kind Words for the Censors" by Hugh A. Mulligan; "Those Awards Have Their Limitations" by Larry Fortner; "Obituaries Are…

  3. Message from the Editor

    NASA Astrophysics Data System (ADS)

    Stambaugh, Ronald D.

    2014-01-01

    This last year being an odd numbered year, the pages of Nuclear Fusion saw a large influx of expanded papers from the 2012 Fusion Energy Conference in San Diego. Many papers have focused on the scientific and technical challenges posed by ITER. Contributions are steadily increasing from the new superconducting tokamaks in Asia. The ITER Project continues to move ahead. Construction at the Cadarache site is quite remarkable. Buildings completed include the huge Poloidal Field Coils Winding Facility and the Headquarters building, which has been occupied by the ITER staff. Work is progressing on the Assembly building and the Cryostat Workshop. The base of the tokamak complex is being laid. Besides the construction that is taking place and will take place at the site, components from around the world have to navigate the complex route from Marseilles to the site. A test convoy replicating the dimensions and weights of the most exceptional ITER loads successfully traversed that route in 2013. We are pleased to report that the IAEA and ITER have finalized the agreement for ITER authors to publish papers in Nuclear Fusion . Nuclear Fusion is proud to continue its key role in providing the leading forum for the documentation of scientific progress and exchange of research results internationally toward fusion energy. Refereeing The Nuclear Fusion editorial office appreciates greatly the effort made by our referees to sustain the high quality of the journal. Since January 2005, we have been offering the most active referees over the past year a personal subscription to Nuclear Fusion with electronic access for one year, free of charge. We have excluded our Board Members, Guest Editors of special editions and those referees who were already listed in previous years. The following people have been selected: J.M. Canik, Oak Ridge National Laboratory, USA I.T. Chapman, Culham Centre for Fusion Energy, UK L.-G. Eriksson, Commission of the European Communities, Belgium T. Evans

  4. EDITORIAL: Editor's Introduction

    NASA Astrophysics Data System (ADS)

    Blackburn, D. A.

    1990-01-01

    Since its first issue in 1965 Metrologia has had just three editors, a history of tenure which suggests that those who hold the post find in it sufficient to interest, occupy, challenge and amuse them. I see no reason to doubt that this happy circumstance will continue and look forward to my own period as editor with the intention of retaining, insofar as I am able to interpret them, the best traditions the journal has established so far. As I take up my editorial duties I have become aware that surrounding Metrologia there is a small community of authors, reviewers and readers on whose support the success of the journal entirely depends. It is a community in which the roles change daily with some of its members engaged, even simultaneously, as reader, reviewer and author. I am well aware that the goodwill extended to me as I enter this community is in no small part due the efforts of the outgoing editor, Dr Ralph Hudson, whose easy, engaging and courteous, yet firm, relationship with authors and reviewers emerges clearly from editorial correspondence. I thank him for that he has done and wish him an active and happy retirement. A short foray into the records of Metrologia shows - in the first editorial - that four main kinds of article were originally envisaged: research articles likely to contribute to progress in fundamental scientific measurements, reports of experiments or techniques of particular importance or originality in the area of secondary measurement, articles concerning the decisions of the Comité International des Poids et Mesures, and review articles. No balance was specified but a priority was assigned to articles dealing with fundamental metrology. Of the four categories, the first two represent the core of Metrologia's activity and largely determine its reputation as a publication. For this reason, editorial implementation of the policy set by the CIPM is mainly exercised through the operation of a reviewing system which is intentionally strict

  5. An Interview with Michael Maloney.

    ERIC Educational Resources Information Center

    Tucker, Bruce

    1989-01-01

    Michael Maloney--Appalachian advocate, activist, and community organizer in Cincinnati's Over-the-Rhine neighborhood since the mid-1960s--discusses two decades of racial relations in this blighted inner city neighborhood, and the emergence of an urban Appalachian "ethnic" consciousness among transplanted mountain people. Contains 15 references.…

  6. Michael Sadler and Comparative Education

    ERIC Educational Resources Information Center

    Phillips, David

    2006-01-01

    This paper examines the work in education of Michael Sadler (1861-1943). It covers his early years in Oxford, his time as director of the Department of Special Inquiries and Reports, his periods as professor of education in Manchester and as vice-chancellor in Leeds, and his return to Oxford as Master of University College, and it assesses the…

  7. Q&A: Michael Honey

    ERIC Educational Resources Information Center

    Helicher, Karl

    2007-01-01

    The mid-1960s saw civil rights victories in Congress during Lyndon B. Johnson's presidency. In "Going Down Jericho Road," Michael Honey wrote how Martin Luther King Jr.'s final focus showed that the struggle for black and working class parity continued. The 1968 Memphis sanitation workers strike was a gritty struggle won in the streets by a host…

  8. Michael Beitz: Objects of Communication

    ERIC Educational Resources Information Center

    Hoefferle, Mary

    2014-01-01

    For this Instructional Resource, the author interviewed contemporary sculptor Michael Beitz, who uses art to explore the role of designed objects in human communication and emotional experience. This column was written in response to calls for using Enduring Understandings/Big Ideas (National Coalition for Core Arts Standards, 2013; Stewart &…

  9. A Conversation with Michael Byram

    ERIC Educational Resources Information Center

    Wagner, Manuela

    2013-01-01

    In language teaching, it has been universally acknowledged that students need not just knowledge and skill in the grammar of a language but also the ability to use the language in socially and culturally appropriate ways. In this article Michael Byram, who has been working on Intercultural Competence for quite some time in a variety of different…

  10. Letter from the Editor

    NASA Astrophysics Data System (ADS)

    Strassmeier, Klaus G.

    2009-01-01

    As of 2007, Astronomische Nachrichten -- Astronomical Notes has reached its all-time high regarding the ISI journal impact factor, with an impressive increase of 60% compared to 2005. We now rank at 1,461, as shown in the statistics below. This is solely due to the increased quality of the published articles: In 2006, Astronomische Nachrichten -- Astronomical Notes published 208 research papers and received 1,033 citations -- five citations per paper on average. In 2007, we have published 177 research papers with roughly the same number of citations. In co-operation with Wiley InterScience we have achieved an average online publication time of just 4.5 months. We hope that the year 2008 will be comparably prosperous. As in the past, publication in Astronomische Nachrichten -- Astronomical Notes continues to be free of charge. Also, all articles of the first issue of each volume can be downloaded free of charge, as can all articles labelled ``Editor's Choice'', which are additionally featured with a color image on the front cover.

  11. Letter from the Editor

    NASA Astrophysics Data System (ADS)

    Strassmeier, Klaus G.

    2008-01-01

    As of 2006, Astronomische Nachrichten -- Astronomical Notes has reached its all-time high regarding the ISI journal impact factor, with an impressive increase of 60% compared to 2005. We now rank at position 1,399, as shown in the statistics below. This is solely due to the increased number and quality of published articles: In 2006, Astronomische Nachrichten -- Astronomical Notes published 208 research papers and received 1,033 citations -- five citations per paper on average. In 2007, we have published 177 research papers, and one may be curious to see how their factor will develop. In co-operation with Wiley InterScience we have achieved an average o nline publication time of just 4.5 months. As in the past, publication in Astronomische Nachrichten -- Astronomical Notes} continues to be free of charge. Also, all articles of the first issue of each volume can be downloaded free of charge, as can all articles labelled ``Editor's Choice'', which are additionally featured with a color image on the front cover.

  12. Michael Faraday vs. the Spiritualists

    NASA Astrophysics Data System (ADS)

    Hirshfeld, Alan

    2006-12-01

    In the 1850s, renowned physicist Michael Faraday launched a public campaign against pseudoscience and spiritualism, which were rampant in England at the time. Faraday objected especially to claims that electrical or magnetic forces were responsible for paranormal phenomena, such as table-spinning and communication with the dead. Using scientific methods, Faraday unmasked the deceptions of spiritualists, clairvoyants and mediums and also laid bare the credulity of a public ill-educated in science. Despite his efforts, Victorian society's fascination with the paranormal swelled. Faraday's debacle anticipates current controversies about public science education and the interface between science and religion. This episode is one of many described in the new biography, The Electric Life of Michael Faraday (Walker & Co.), which chronicles Faraday's discoveries and his unlikely rise from poverty to the pinnacle of the English science establishment.

  13. Organocatalytic aza-Michael/retro-aza-Michael reaction: pronounced chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction.

    PubMed

    Cai, Yong-Feng; Li, Li; Luo, Meng-Xian; Yang, Ke-Fang; Lai, Guo-Qiao; Jiang, Jian-Xiong; Xu, Li-Wen

    2011-05-01

    A detailed experimental investigation of an aza-Michael reaction of aniline and chalcone is presented. A series of Cinchona alkaloid-derived organocatalysts with different functional groups were prepared and used in the aza-Michael and retro-aza-Michael reaction. There was an interesting finding that a complete reversal of stereoselectivity when a benzoyl group was introduced to the cinchonine and cinchonidine. The chirality amplification vs. time proceeds in the quinine-derived organocatalyst containing silicon-based bulky group, QN-TBS, -catalyzed aza-Michael reaction under solvent-free conditions. In addition, we have demonstrated for the first time that racemization was occurred in suitable solvents under mild conditions due to retro-aza-Michael reaction of the Michael adduct of aniline with chalcone. These indicate the equilibrium of retro-aza-Michael reaction and aza-Michael reaction produce the happening of chirality amplification in aza-Michael reaction and racemization via retro-aza-Michael reaction under different conditions, which would be beneficial to the development of novel chiral catalysts for the aza-Michael reactions.

  14. Guest Editor's introduction

    NASA Astrophysics Data System (ADS)

    1996-03-01

    pleasure to be Guest Editor and I look forward to future developments in this growing research area and expositions in Distributed Systems Engineering. Peter G Harrison Imperial College, London

  15. Message from the Editor

    NASA Astrophysics Data System (ADS)

    Stambaugh, Ronald D.

    2013-01-01

    reviewed five manuscripts in the period November 2011 to December 2012 and provided excellent advice to the authors. We have excluded our Board Members, Guest Editors of special editions and those referees who were already listed in recent years. The following people have been selected: Marina Becoulet, CEA-Cadarache, France Jiaqui Dong, Southwestern Institute of Physics, China Emiliano Fable, Max-Planck-Institut für Plasmaphysik, Germany Ambrogio Fasoli, Ecole Polytechnique Federale de Lausanne, Switzerland Eric Fredrickson, Princeton Plasma Physics Laboratory, USA Manuel Garcia-Munoz, Max-Planck-Institut fuer Plasmaphysik, Germany William Heidbrink, California University, USA Katsumi Ida, National Inst. For Fusion Science, Japan Peter Stangeby, Toronto University, Canada James Strachan, Princeton Plasma Physics Laboratory, USA Victor Yavorskij, Ukraine National Academy of Sciences, Ukraine In addition, there is a group of several hundred referees who have helped us in the past year to maintain the high scientific standard of Nuclear Fusion. At the end of this issue we give the full list of all referees for 2012. Our thanks to them!

  16. New Editors for AGU Journals

    NASA Astrophysics Data System (ADS)

    Panning, Jeanette

    2014-10-01

    John Orcutt, the editor in chief of Earth and Space Science, has filled in his editorial board with Andrea Donnellan (University of Southern California), Jonathan H. Jiang (NASA Jet Propulsion Laboratory, California Institute of Technology), Benoît Pirenne (University of Victoria, BC, Canada), and Frank Vernon (University of California, San Diego).

  17. Jack Michael's Motivation

    ERIC Educational Resources Information Center

    Miguel, Caio F.

    2013-01-01

    Among many of Jack Michael's contributions to the field of behavior analysis is his behavioral account of motivation. This paper focuses on the concept of "motivating operation" (MO) by outlining its development from Skinner's (1938) notion of "drive." Conceptually, Michael's term helped us change our focus on…

  18. Method for promoting Michael addition reactions

    DOEpatents

    Shah, Pankaj V.; Vietti, David E.; Whitman, David William

    2010-09-21

    Homogeneously dispersed solid reaction promoters having an average particle size from 0.01 .mu.m to 500 .mu.m are disclosed for preparing curable mixtures of at least one Michael donor and at least one Michael acceptor. The resulting curable mixtures are useful as coatings, adhesives, sealants and elastomers.

  19. Ron Dittemore and Michael Kostelnik

    NASA Technical Reports Server (NTRS)

    2003-01-01

    Ronald D. Dittemore (right), a 26-year NASA veteran, announces his intention to step aside as the Space Shuttle Program Manager at the Johnson Space Center in Houston to pursue other opportunities. Also pictured at the Washington, DC announcement is Michael Kostelnik, Deputy Associate Administrator for the Space Shuttle and International Space Station Programs. Dittemore, who has served as the Shuttle Program Manager for more than four years, will remain in his current position until the Columbia Accident Investigation Board finishes its investigation and a complete 'Return to Flight' path has been established. Dittemore retired recently, he had publicly planned to do so before the accident. For more information on STS-107, please see GRIN Columbia General Explanation

  20. SIERRA Editor v. 1.2.1

    SciTech Connect

    Hoffman, Edward; Friedman-Hill, Ernest; Gibson, Marcus; Heinstein, Martin; & Whittford, Greg

    2010-03-24

    The SIERRA Editor is a syntax editor for text-based input decks for the SIERRA modeling and simulations codes. The SIERRA Editor provides color coded syntax, error checking, hyperlink navigation to referenced entities (e.g. functions and materials), and visual verification of mesh entity references (blocks, sidesets, and nodesets). The SIERRA Editor helps modeling and simulation analysts who use the SIERRA codes to produce syntactically correct input decks.

  1. New Editors, Editorial Advisory Board for Eos

    NASA Astrophysics Data System (ADS)

    Richman, Barbara T.

    2010-11-01

    Eos has two new editors and, with this issue, a revitalized Editorial Advisory Board. Christina M. S. Cohen, of the California Institute of Technology, is the new editor for space sciences. She succeeds Manuel Grande, who had served since 2006. Carol A. Stein, of the University of Illinois at Chicago, is the new editor for solid Earth. She succeeds John W. Geissman, who has been solid Earth editor since 2001; he will continue through the end of 2010.

  2. Test pilot Michael R. Swann

    NASA Technical Reports Server (NTRS)

    1978-01-01

    Michael R. Swann joined the National Aeronautics and Space Administration's Dryden Flight Research Center on June 5, 1978, transferring from the NASA's Johnson Space Center, Houston, Texas, as a research pilot. Swann attended North Dakota State University, Fargo, North Dakota, from September 1968 to February 1977, where he earned his Masters in Physics. He was a member of three national honorary scholastic fraternities. Prior to joining NASA Swann served concurrently as an Aerospace Defense Command Interceptor pilot in the Air National Guard for five years and as a college physics instructor at North Dakota State University for two years. While at Johnson Space Center Mike was a pilot on high altitude earth resources and air sampling missions. He was also an instructor and check pilot for the Astronaut Space Flight Readiness Training program. As a Dryden research pilot Mike was involved with the F-111 #778 Transonic Aircraft Technology (TACT) program, F-15 # 281 Shuttle Tile tests, programs on the F-8C #802 and the PA-30 #808 Remotely Piloted Research Vehicle. He flew the Bell 47G #822 helicopter in support of research with the three-eighths-scale F-15 Spin Research Vehicle. On March 28, 1979, Mike made a pilot familiarization flight in the YF-12A #935. He also flew support flights in the F-104, C-47, T-37, T-38, and the Jetstar aircraft. Michael R. Swann was born June 5, 1949, in Fargo, North Dakota; he was fatally injured in a recreational glider accident on July 28, 1981, near California City, California.

  3. A general organocatalyzed Michael-Michael cascade reaction generates functionalized cyclohexenes.

    PubMed

    McGarraugh, Patrick G; Jones, Joshua H; Brenner-Moyer, Stacey E

    2011-08-01

    Although β-dicarbonyl compounds are regularly employed as Michael donors, intermediates arising from the Michael addition of unsaturated β-ketoesters to α,β-unsaturated aldehydes are susceptible to multiple subsequent reaction pathways. We designed cyclic unsaturated β-ketoester substrates that enabled the development of the first diphenyl prolinol silyl ether catalyzed Michael-Michael cascade reaction initiated by a β-dicarbonyl Michael donor to form cyclohexene products. The reaction conditions we developed for this Michael-Michael cascade reaction were also amenable to a variety of linear unsaturated β-ketoester substrates, including some of the same linear unsaturated β-ketoester substrates that were previously ineffective in Michael-Michael cascade reactions. These studies thus revealed that a change in simple reaction conditions, such as solvent and additives, enables the same substrate to undergo different cascade reactions, thereby accessing different molecular scaffolds. These studies also culminated in the development of a general organocatalyzed Michael-Michael cascade reaction that generates highly functionalized cyclohexenes with up to four stereocenters, in up to 97% yield, 32:1 dr, and 99% ee, in a single step from a variety of unsaturated β-ketoesters.

  4. Line-Editor Computer Program

    NASA Technical Reports Server (NTRS)

    Scott, Peter J.

    1989-01-01

    ZED editing program for DEC VAX computer simple, powerful line editor for text, program source code, and nonbinary data. Excels in processing of text by use of procedure files. Also features versatile search qualifiers, global changes, conditionals, online help, hexadecimal mode, space compression, looping, logical combinations of search strings, journaling, visible control characters, and automatic detabbing. Users of Cambridge implementation devised such ZED procedures as chess games, calculators, and programs for evaluating pi. Written entirely in C.

  5. Michael Thackeray on Lithium-air Batteries

    ScienceCinema

    Thackeray, Michael

    2016-07-12

    Michael Thackeray, Distinguished Fellow at Argonne National Laboratory, speaks on the new technology Lithium-air batteries, which could potentially increase energy density by 5-10 times over lithium-ion batteries.

  6. ASK Talks with Dr. Michael Hecht

    NASA Technical Reports Server (NTRS)

    Hecht, Michael

    2003-01-01

    Michael Hecht has been a member of NASA's Jet Propulsion Laboratory (JPL) staff since 1982. He is currently Project Manager and co-investigator for the Mars Environmental Compatibility Assessment (MECA)

  7. Diastereodivergent organocatalytic asymmetric vinylogous Michael reactions.

    PubMed

    Li, Xin; Lu, Min; Dong, Yun; Wu, Wenbin; Qian, Qingqing; Ye, Jinxing; Dixon, Darren J

    2014-07-24

    One of the major challenges of modern asymmetric catalysis is the ability to selectively control the formation of all diastereoisomers of reaction products possessing multiple stereocenters. Pioneers of such diastereodivergent catalytic asymmetric processes have focused on reactions where the newly formed stereogenic centres are proximal to the active carbonyl group. To date, however, diastereodivergent reactions at remote positions remain an unmet challenge. Herein, we describe a catalyst-controlled diastereodivergence in the formation of remote stereocenters in the direct vinylogous Michael reactions of β, γ-unsaturated butenolides to α, β-unsaturated ketones. The reactions are enabled by two complementary, non-enantiomeric multifunctional catalysts, which mutually activate and organise both reactants, affording either the syn- or anti-adduct with high diastereo- and enantioselectivity. These two catalytic systems are also applicable in the Mukaiyama-Michael reactions and tandem Michael-Michael reactions.

  8. ATV2 Interview with Michael Suffredini

    NASA Video Gallery

    International Space Station Manager Michael Suffredini answers questions about the European Space Agency’s second Automated Transfer Vehicle (ATV2), Johannes Kepler, set to launch from a launch p...

  9. Enantioselective synthesis of hindered cyclic dialkyl ethers via catalytic oxa-Michael/Michael desymmetrization†

    PubMed Central

    Corbett, Michael T.; Johnson, Jeffrey S.

    2014-01-01

    An asymmetric oxa-Michael/Michael cascade reaction of p-quinols and α,β-unsaturated aldehydes provides access to hindered dialkyl ethers. A highly enantioselective oxa-Michael addition of a tertiary alcohol precedes an intramolecular cyclohexadienone desymmetrization, which allows for the concomitant formation of four contiguous stereocenters in a single step. The highly functionalized bicyclic frameworks are rapidly obtained from simple starting materials with good diastereoselection and serve as valuable precursors for further manipulation. PMID:24683449

  10. Reversible Michael additions: covalent inhibitors and prodrugs.

    PubMed

    Johansson, Martin H

    2012-11-01

    Covalent inhibition is an efficient molecular mechanism for inhibiting enzymes or modulating the function of proteins and is found in the action of many drugs and biologically active natural products. However, it is has been less appreciated that the formation of covalent bonds can be reversible or irreversible. This review focuses on biologically active compounds that are Michael acceptors and how the reversible nature of the Michael addition reaction influences biological activity and how this can be exploited in designing prodrugs.

  11. [Early career of Michael Sendivogius].

    PubMed

    Prinke, Rafał T

    2012-01-01

    One of the most influential alchemical authors of the early modern period was Michael Sendivogius whose early life is shrouded in mystery. He may be labelled the most famous Polish scientific writer between Copernicus and Marie Skłodowska-Curie, but because of the difficulties involved in researching the biography of any alchemist, there has been relatively little interest in him among Polish historians. The early work of Roman Bugaj (author of the still fundamental monograph) and Włodzimierz Hubicki (who made his research available to the international community) has been continued only by the English-born Zbigniew Szydło and the author of this article. The roots of many legends about Sendivogius were three mid-17th century short biographies, none of which is trustworthy, so it is crucial to verify the received myth and the version constructed in the 1960's and 1970's with primary sources and evidence from the recent "new historiography of alchemy". The present article examines them in the light of newly discovered sources and reinterpretation of the old ones. The genealogy of the Sedzimir family is discussed at length to show that Sendivogius most probably was not its member but only a pretender in order to assume (or prove) the status of a nobleman. Several possible hypotheses about his origins are presented. He is known to have studied at three universities (Leipzig, Vienna and Altdorf) but authors of early panegyrics dedicated to Sendivogius list more universities which he may have attended. The most interesting is that of Cambridge, listed as the first one, because practically no Poles or Czechs went there at the time. Finally, his marriage to Veronica Stiebar, a wealthy widow of a Franconian knightly family, and her interesting family relationships (links to Erasmus, Camerarius, Paracelsus and the original Doctor Faustus) are discussed. The period covered is that before Sendivogius moved to Prague in about 1597, having already been a courtier of Rudolf II

  12. Principles of Chemistry (by Michael Munowitz)

    NASA Astrophysics Data System (ADS)

    Kovac, Reviewed By Jeffrey

    2000-05-01

    At a time when almost all general chemistry textbooks seem to have become commodities designed by marketing departments to offend no one, it is refreshing to find a book with a unique perspective. Michael Munowitz has written what I can only describe as a delightful chemistry book, full of conceptual insight, that uses a novel and interesting pedagogic strategy. This is a book that has much to recommend it. This is the best-written general chemistry book I have ever read. An editor with whom I have worked recently remarked that he felt his job was to help authors make their writing sing. Well, the writing in Principles of Chemistry sings with the full, rich harmonies and creative inventiveness of the King's Singers or Chanticleer. Here is the first sentence of the introduction: "Central to any understanding of the physical world is one discovery of paramount importance, a truth disarmingly simple yet profound in its implications: matter is not continuous." This is prose to be savored and celebrated. Principles of Chemistry has a distinct perspective on chemistry: the perspective of the physical chemist. The focus is on simplicity, what is common about molecules and reactions; begin with the microscopic and build bridges to the macroscopic. The author's perspective is clear from the organization of the book. After three rather broad introductory chapters, there are four chapters that develop the quantum mechanical theory of atoms and molecules, including a strong treatment of molecular orbital theory. Unlike many books, Principles of Chemistry presents the molecular orbital approach first and introduces valence bond theory later only as an approximation for dealing with more complicated molecules. The usual chapters on descriptive inorganic chemistry are absent (though there is an excellent chapter on organic and biological molecules and reactions as well as one on transition metal complexes). Instead, descriptive chemistry is integrated into the development of

  13. Principles of Chemistry (by Michael Munowitz)

    NASA Astrophysics Data System (ADS)

    Kovac, Reviewed By Jeffrey

    2000-05-01

    At a time when almost all general chemistry textbooks seem to have become commodities designed by marketing departments to offend no one, it is refreshing to find a book with a unique perspective. Michael Munowitz has written what I can only describe as a delightful chemistry book, full of conceptual insight, that uses a novel and interesting pedagogic strategy. This is a book that has much to recommend it. This is the best-written general chemistry book I have ever read. An editor with whom I have worked recently remarked that he felt his job was to help authors make their writing sing. Well, the writing in Principles of Chemistry sings with the full, rich harmonies and creative inventiveness of the King's Singers or Chanticleer. Here is the first sentence of the introduction: "Central to any understanding of the physical world is one discovery of paramount importance, a truth disarmingly simple yet profound in its implications: matter is not continuous." This is prose to be savored and celebrated. Principles of Chemistry has a distinct perspective on chemistry: the perspective of the physical chemist. The focus is on simplicity, what is common about molecules and reactions; begin with the microscopic and build bridges to the macroscopic. The author's perspective is clear from the organization of the book. After three rather broad introductory chapters, there are four chapters that develop the quantum mechanical theory of atoms and molecules, including a strong treatment of molecular orbital theory. Unlike many books, Principles of Chemistry presents the molecular orbital approach first and introduces valence bond theory later only as an approximation for dealing with more complicated molecules. The usual chapters on descriptive inorganic chemistry are absent (though there is an excellent chapter on organic and biological molecules and reactions as well as one on transition metal complexes). Instead, descriptive chemistry is integrated into the development of

  14. Direct Diastereo- and Enantioselective Vinylogous Michael Additions of Linear Enones.

    PubMed

    Guo, Qunsheng; Fraboni, Americo J; Brenner-Moyer, Stacey E

    2016-06-01

    A direct vinylogous Michael addition using linear vinylogous Michael donors has been developed. Notably, even γ-substituted Michael donors cleanly afforded γ-alkylated products in high yield and ee by this method. Moreover, control experiments revealed that, for these and related linear vinylogous Michael donors, the size of the Michael acceptor strongly influences whether α- or γ-alkylation occurs, not simply blocking effects of cocatalysts as suggested previously.

  15. EDITORIAL: Message from the Editor Message from the Editor

    NASA Astrophysics Data System (ADS)

    Thomas, Paul

    2011-01-01

    As usual, being an even year, the 23rd IAEA Fusion Energy Conference took place at Daejeon, Korea. The event was notable not just for the quality of the presentations but also for the spectacular opening ceremony, in the presence of the Prime Minister, Kim Hwang-sik. The Prime Minister affirmed the importance of research into fusion energy research and pledged support for ITER. Such political visibility is good news, of course, but it brings with it the obligation to perform. Fortunately, good performance was much in evidence in the papers presented at the conference, of which a significant proportion contain 'ITER' in the title. Given this importance of ITER and the undertaking by the Nuclear Fusion journal to publish papers associated with Fusion Energy Conference presentations, the Nuclear Fusion Editorial Board has decided to adopt a simplified journal scope that encompasses technology papers more naturally. The scope is available from http://iopscience.iop.org/0029-5515/page/Journal%20information but is reproduced here for clarity: Nuclear Fusion publishes articles making significant advances to the field of controlled thermonuclear fusion. The journal scope includes: the production, heating and confinement of high temperature plasmas; the physical properties of such plasmas; the experimental or theoretical methods of exploring or explaining them; fusion reactor physics; reactor concepts; fusion technologies. The key to scope acceptability is now '....significant advances....' rather than any particular area of controlled thermonuclear fusion research. It is hoped that this will make scope decisions easier for the Nuclear Fusion office, the referees and the Editor.The Nuclear Fusion journal has continued to make an important contribution to the research programme and has maintained its position as the leading journal in the field. This is underlined by the fact that Nuclear Fusion has received an impact factor of 4.270, as listed in ISI's 2009 Science Citation

  16. Examining Editor-Author Ethics: Real-World Scenarios from Interviews with Three Journal Editors

    ERIC Educational Resources Information Center

    Amare, Nicole; Manning, Alan

    2009-01-01

    Those who submit manuscripts to academic journals may benefit from a better understanding of how editors weigh ethics in their interactions with authors. In an attempt to ascertain and to understand editors' ethics, we interviewed 3 current academic journal editors of technical and/or business communication journals. We asked them about the…

  17. ESO Vacancy - Editor (EDG 604)

    NASA Astrophysics Data System (ADS)

    2002-09-01

    Assignment: Within the ESO Education and Public Relations Department team, your main tasks and responsibilities will comprise: • Development, update and maintenance of the comprehensive ESO Outreach website in its new look, including preparation of related material (texts, images, etc.) to be displayed; • Design, layout and production of the ESO quarterly journal “The Messenger” (e.g. image selection and processing, technical editing, etc.), in close collaboration with the Messenger editor; • Conception and production of promotional brochures, posters and other EPR products, in close collaboration with the Head of the Education and Public Relations Dept. of ESO Press Releases and various high-level publications, including the ESO Annual Report.

  18. Letter to Editor - "Reply to RP Heaney"

    Technology Transfer Automated Retrieval System (TEKTRAN)

    A letter to the editor was submitted in reply to a letter written to the editor of the American Journal of Clinical Nutrition regarding a recent publication (Hunt, CD. and Johnson, LK. Calcium requirements: new estimations for men and women by cross-sectional statistical analyses of calcium balance...

  19. Good editorial practice: editors as educators.

    PubMed

    Marusić, M; Marusić, A

    2001-04-01

    There may be valuable research going on in the developing and financially less-privileged countries, but it usually does not reach international visibility, in spite of a large number of scientific journals in these countries. Such journals are not only invisible but, by perpetuating a vicious circle of inadequacy, may be directly damaging to the local science and research culture. We call for an international action to help journal editors in less privileged countries. International associations of editors may be leaders of these activities by defining, promoting, and perhaps controlling good editorial practice, as a main criterion for international recognition of a journal. However, the editors of small journals have the power and moral obligation to become a stronghold of quality and advancement in their scientific community. Their educational "tools" are editorial integrity and author-friendly policy. Editors can teach the authors study design, statistical analysis, precision, punctuality, research integrity, style and format of writing, and other aspects of scientific communication. The editors of "big", mainstream scientific journals can act as global educators, teaching and providing guidance to editors of small journals. The editors from developed countries as leaders, and editors from less advantageous environments as teachers are the key figures in shaping research communication in less privileged scientific communities.

  20. Linguistic Prescriptivism in Letters to the Editor

    ERIC Educational Resources Information Center

    Lukac, Morana

    2016-01-01

    The public's concern with the fate of the standard language has been well documented in the history of the complaint tradition. The print media have for centuries featured letters to the editor on questions of language use. This study examines a corpus of 258 language-related letters to the editor published in the English-speaking print media. By…

  1. A Synonym for Editor Must Be Leader.

    ERIC Educational Resources Information Center

    Konkle, Bruce E.

    2003-01-01

    Contends that in scholastic journalism, the editor might not be the best writer, designer, or photographer, but he or she must have a vision of what the final publication should be. Lists the following desirable traits of an editor: strong work ethic; motivation; organization; background knowledge; and responsibility. (PM)

  2. Technical Editor Looks at Technical Writing.

    ERIC Educational Resources Information Center

    Smith, Howard (Bud)

    1982-01-01

    The author explores problems in technical writing, the editor's role, and the author-editor relationship. He presents a list of basic writing rules to help the technical writer achieve success. These involve subject matter, deadlines, purpose, topic sentences, arrangement, clarity, idea development, examples, vocabulary, reading level, and…

  3. EDITORIAL: Message from the Editor

    NASA Astrophysics Data System (ADS)

    Thomas, Paul

    2009-01-01

    Plasmaphysik, Germany) V. Philipps (Forschungszentrum Juelich, Germany) S. Zweben (Princeton Plasma Physics Laboratory, USA) Y. Hirano (National Institute of Advanced Industrial Science and Technology, Japan) Y. Takase (Tokyo University, Japan) In addition there is a group of several hundred referees who have helped us in the past year to maintain the high scientific standard of Nuclear Fusion. At the end of this issue we give the full list of all referees for 2008. Our thanks to them! Authors The winner of the 2007 award was Clemente Angioni for the paper entitled `Density response to central electron heating: theoretical investigations and experimental observations in ASDEX Upgrade' (Nucl. Fusion 44 8277-845). The winner of the 2008 Nuclear Fusion award is Todd Evans et al for the paper `Suppression of large edge localized modes with edge resonant magnetic fields in high confinement DIII-D plasmas' (Nucl. Fusion 45 595-607). The awards were presented by the IAEA Deputy Director General, Werner Burkart, and the Chairman of the Board of Editors, Mitsuru Kikuchi, on 16 October 2008 at the 22nd IAEA Fusion Energy Conference in Geneva, Switzerland. Given the topicality of these papers for the ITER design, it is a matter of pride to the journal that the work should be published in Nuclear Fusion. Reviews Like many who have worked for a long time in the field, I still make use of Nuclear Fusion Reviews that go back 20 or 30 years. It is particularly useful, therefore, that the Board of Editors has been working to re-activate the review programme. The first fruits will appear in this issue, in the form of `A review of zonal flow experiments', by Akihide Fujisawa. The special procedures for Reviews should be noted: most specifically that they should normally be commissioned by the Board of Editors. However, not only is the Board of Editors working on a programme but I am sure that they would be pleased to consider suggestions for review subjects. Letters The reputation of Nuclear

  4. Squaramide-tertiary amine catalyzed asymmetric cascade sulfa-Michael/Michael addition via dynamic kinetic resolution: access to highly functionalized chromans with three contiguous stereocenters.

    PubMed

    Yang, Wen; Yang, Yi; Du, Da-Ming

    2013-03-15

    An efficient asymmetric cascade sulfa-Michael/Michael addition reaction catalyzed by a chiral bifunctional squaramide-tertiary amine catalyst has been developed. This organocatalytic cascade reaction provides easy access to highly functionalized chromans with three contiguous stereocenters, including one quaternary center. In addition, a novel cascade sulfa Michael/retro-sulfa-Michael/sulfa-Michael/Michael reaction process, involving dynamic kinetic resolution, is described.

  5. Michael Slote and "Sentimentalist Moral Education"

    ERIC Educational Resources Information Center

    Wren, Thomas

    2010-01-01

    Although I think most of what Michael Slote asserts in his article "Sentimentalist moral education" is correct, I worry about three important ideas that are conspicuous by their absence. The first is the possibility that human emotions and feelings are inherently cognitive, which is never considered in his psychological account of empathy. The…

  6. Solving the Housing Equation: Michael P. Johnson

    ERIC Educational Resources Information Center

    Roach, Ronald

    2005-01-01

    Dr. Michael P. Johnson, an associate professor of management science and urban affairs at the H. John Heinz III School of Public Policy and Management at Carnegie Mellon University in Pittsburgh, is taking management science tools and innovative information technology applications to the housing field. Concerned that organizations that develop and…

  7. International Humanitarian Award: Michael G. Wessells

    ERIC Educational Resources Information Center

    American Psychologist, 2009

    2009-01-01

    Michael G. Wessells, recipient of the International Humanitarian Award, is cited for his pioneering and sustained contributions to the protection of children affected by armed conflict and to the development of international guidelines for the provision of community-based, culturally responsive psychosocial support in emergencies. Wessells has…

  8. Michael Gorman vs. Web 2.0

    ERIC Educational Resources Information Center

    Chronicle of Higher Education, 2007

    2007-01-01

    In a much-discussed series of postings on the Encyclopaedia Britannica Online Web site, Michael Gorman, former president of the American Library Association and the recently retired dean of library services at California State University at Fresno, argues that the "often-anarchic world of the Internet" is saturating people's culture with a "tide…

  9. Astronaut Michael L. Coats with camera.

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Astronaut Michael L. Coats positions himself for a photographic briefing during a training session for 41-D crewmembers in the Shuttle one-g trainer at the Johnson Space Center (JSC). Coats will assume pilot duties aboard the Space Shuttle Discovery for the scheduled seven-day 41-D mission in late June. This photograph was taken for NASA by Otis Imboden.

  10. Michael Walzer's Politics, in Theory and Practice

    ERIC Educational Resources Information Center

    Williams, Jeffrey J.

    2012-01-01

    Before all the talk about "public intellectuals," Michael Walzer was one. For 50 years, he has gone back and forth between positions at Princeton and Harvard Universities and then at the Institute for Advanced Study, in Princeton, New Jersey, where he is now emeritus. His writings appear regularly in "Dissent" magazine, which he has co-edited for…

  11. Comments on Michael (1993): Establishing Operations

    ERIC Educational Resources Information Center

    Moore, J.

    2013-01-01

    The present comments concern Michael's concept of motivative variables, and the implications of that concept for our understanding of the nature of reinforcement as well as the extinction of responses maintained through positive and negative reinforcement. We note that both extinction and altering motivative variables decrease responding, but…

  12. Michael and Malott's dialog on linguistic productivity.

    PubMed

    Michael, Jack; Malott, Richard W

    2003-01-01

    This is an informal dialog between Jack Michael and Dick Malott inspired by Malott's commentary (In press) on Relational Frame Theory: A Post-Skinnerian Account of Human Language and Cognition (Hayes, Barnes-Holmes, Roche; 2001). Topics range from psychologist Skinner to linguist Hockett and from the Skinner box to verbal behavior (AKA language).

  13. Against Dogma: A Reply to Michael Swan.

    ERIC Educational Resources Information Center

    Widdowson, H. G.

    1985-01-01

    Replies to two articles by Michael Swan entitled "A Critical Look at the Communicative Approach." Argues that Swan presents a distorted version of the communicative approach so as to present his own ideas more effectively and that he fails to offer evidence for his position on the practice of English language teaching. (SED)

  14. Reframing Michael Scott: Exploring Inappropriate Workplace Communication

    ERIC Educational Resources Information Center

    Schaefer, Zachary A.

    2010-01-01

    Individuals who work in professional settings interact with others who may exhibit a variety of cultural beliefs and decision-making approaches. Page (2007) argues that cognitive diversity (i.e., how people approach and attempt to solve problems) is a vital asset in effective organizations. Michael Scott, who portrays the inept main character on…

  15. 4. Photocopy of inkandwatercolor drawing (from St. Michael's Church) Rambusch, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Photocopy of ink-and-watercolor drawing (from St. Michael's Church) Rambusch, illustrator ca. 1932-37 INTERIOR, LOOKING NORTHEAST - St. Michael's Catholic Church, 519 East Third Street, Madison, Jefferson County, IN

  16. EDITORIAL: Letter from the Editor Letter from the Editor

    NASA Astrophysics Data System (ADS)

    Pashinin, Pavel P.

    2013-01-01

    Dear readers, contributors, and members of the world laser physics community. It is a great honour for us to introduce to you our new publishing partner, IOP Publishing, a subsidiary of the Institute of Physics, United Kingdom. IOP Publishing is a world renowned authority in producing journals, magazines, websites and services that enable researchers and research organizations to present their work to a world-wide audience. Laser Physics, the first English-language scientific journal in Russia, was founded in 1990 on the initiative of Alexander M Prokhorov, a pioneer and leader in laser physics research. Professor Prokhorov served as the first Editor-in-Chief of the journal until 2002. We are proud that it is our 23rd year of publishing Laser Physics and our 10th year of publishing Laser Physics Letters. We would like to honour the memory of our friend, late Professor Igor Yevseyev, whose enthusiasm and unwavering dedication to our journals contributed most significantly to their success. It was initially his idea in 2011 to approach IOP with a partnership proposal. We deeply regret that he is no longer with us as we enter this productive alliance. Now, in partnership with IOP, we are turning a new page in providing world-wide access to the cutting-edge research results in our journals, serving our well established global audience. We see new horizons opening for our journals for years to come and hope that our readers share our enthusiasm and aspirations. Please accept our best wishes for all your new scientific endeavors in the exciting field of laser physics.

  17. Organocatalyzed cascade aza-Michael/Michael addition for the asymmetric construction of highly functionalized spiropyrazolone tetrahydroquinolines.

    PubMed

    Li, Jun-Hua; Du, Da-Ming

    2014-11-01

    An organocatalyzed diastereo- and enantioselective cascade aza-Michael/Michael addition of 2-tosylaminoenones to unsaturated pyrazolones has been developed to afford novel chiral spiropyrazolone tetrahydroquinolines containing three contiguous stereocenters. This cascade reaction proceeded well with 2 mol% chiral bifunctional tertiary amine squaramide catalyst to give the desired products in excellent yields (up to 99%) with excellent diastereoselectivity (up to >25:1 diastereomeric ratio) and high enantioselectivity (up to 91% enantiomeric excess).

  18. EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Nielsch, Kornelius

    2012-01-01

    -review, with the aim to raise the quality of our content, three years later the number of published articles has remained stable at around 220 per year, whilst the number of downloads and citations to the journal has grown. In 2011, three topical issues have been published, on: (Nano)characterization of semiconductor materials and structures (Guest Editor: Alberta Bonanni, University of Linz, Austria) Flexible OLEDs and organic electronics (Guest Editors: Jang-Joo Kim, Min-Koo Han, Cambridge University, UK, and Yong-Young Noh, Seoul National University, Korea) From heterostructures to nanostructures: an 80th birthday tribute to Zhores Alferov (Guest Editor: Dieter Bimberg, Technische Universität Berlin, Germany) For the coming years, I will strongly support that the number of published topical issues will continue on the same level or slightly rise. SST has planned the publication of the following topical issues for 2012: Non-polar and semipolar nitride semiconductors (Guest Editors: Jung Han, Yale University, USA, and Michael Kneissl, Technische Universität Berlin, Germany) Topological insulators (Guest Editors: Alberto Morpurgo, Université de Genève, Switzerland and Björn Trauzettel, Universität Basel, Switzerland) Atomic layer deposition (Guest Editor: Marek Godlewski, Polish Academy of Sciences, Poland) 50th Anniversary of the laser diode (Guest Editors: Mike Adams, Univeristy of Essex, UK and Stephane Calvez, University of Strathclyde, UK) In addition to the traditional topics of SST, I as Editor-in-chief, strongly support and welcome the submission of manuscripts on organic semiconductors, topological insulators, semiconductor nanostructures for photovoltaic, solid-state lighting and energy harvesting, IC application beyond Moore's law and fundamental works on semiconductors based on abundant materials. I am extremely optimistic about the future of SST. I believe that we will raise the standards of acceptance while maintaining the short time from submission to

  19. EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Nielsch, Kornelius

    2012-01-01

    -review, with the aim to raise the quality of our content, three years later the number of published articles has remained stable at around 220 per year, whilst the number of downloads and citations to the journal has grown. In 2011, three topical issues have been published, on: (Nano)characterization of semiconductor materials and structures (Guest Editor: Alberta Bonanni, University of Linz, Austria) Flexible OLEDs and organic electronics (Guest Editors: Jang-Joo Kim, Min-Koo Han, Cambridge University, UK, and Yong-Young Noh, Seoul National University, Korea) From heterostructures to nanostructures: an 80th birthday tribute to Zhores Alferov (Guest Editor: Dieter Bimberg, Technische Universität Berlin, Germany) For the coming years, I will strongly support that the number of published topical issues will continue on the same level or slightly rise. SST has planned the publication of the following topical issues for 2012: Non-polar and semipolar nitride semiconductors (Guest Editors: Jung Han, Yale University, USA, and Michael Kneissl, Technische Universität Berlin, Germany) Topological insulators (Guest Editors: Alberto Morpurgo, Université de Genève, Switzerland and Björn Trauzettel, Universität Basel, Switzerland) Atomic layer deposition (Guest Editor: Marek Godlewski, Polish Academy of Sciences, Poland) 50th Anniversary of the laser diode (Guest Editors: Mike Adams, Univeristy of Essex, UK and Stephane Calvez, University of Strathclyde, UK) In addition to the traditional topics of SST, I as Editor-in-chief, strongly support and welcome the submission of manuscripts on organic semiconductors, topological insulators, semiconductor nanostructures for photovoltaic, solid-state lighting and energy harvesting, IC application beyond Moore's law and fundamental works on semiconductors based on abundant materials. I am extremely optimistic about the future of SST. I believe that we will raise the standards of acceptance while maintaining the short time from submission to

  20. Selective Michael Reaction Controlled by Supersilyl Protecting Group.

    PubMed

    Izumiseki, Atsuto; Yamamoto, Hisashi

    2015-07-20

    Selective Michael reaction of organolithium reagents to supersilyl methacrylate is reported. The method was able to control a single and double Michael addition. The successful termination of the process using the supersilyl protecting group allows for the controlled, chemoselective, and diastereoselective Michael reaction.

  1. Richard Gilbert, Reporter and Assistant City Editor.

    ERIC Educational Resources Information Center

    Bender, Larry

    1988-01-01

    Looks at the experiences of Richard Gilbert, reporter and assistant editor for "The Herald Telephone," a daily newspaper in Bloomington, Indiana, and discusses Gilbert's suggested guidelines for high school journalism advisers. (MS)

  2. Fax etiquette for nurse authors and editors.

    PubMed

    Johnson, S H

    1997-01-01

    Is the facsimile (fax) machine really as great as it seems? Yes, but there is a potential for its misuse. Like all equipment, the fax machine is a tool that needs to be used wisely. This article describes the Do's and Don'ts of using the fax machine to communicate between authors and editors. Tips in this article will help authors and editors to correspond smoothly by fax and use new fax equipment options.

  3. Report of the editors, 2014.

    PubMed

    García Puig, J; Gaspar Alonso-Vega, G; Ríos Blanco, J J

    2015-01-01

    The editors of Revista Clínica Española(Rev Clin Esp) inform on their editorial activity during the last 12 months: (a) Objectives and attainments in 2014, (b) Editorial activity, 2014, and (c) 2013 impact factor. In 2014 we achieved the 5 planned objectives. We have published the 9 programmed issues and 103% of the planned papers according to the usual fixed sections. We emphasize the publication of 29 editorials, 21 of which are signed by prestigious foreign authors. From the first January to the 30th September 2014 we received 421 manuscripts (46.8 manuscripts per month), a slight lower figure to that obtained in 2013 (50.9 manuscripts per month). The acceptance rate of the 404 manuscripts whose editorial process has been concluded was 32.3% (originals, 22.4%). We asked for 315 revisions to 240 reviewers and we received 53.3% revisions in less than two weeks (10.4 days). The mean time to adopt an editorial decision for all manuscripts («accepted»/«rejected») has been 18,3 (less than half than in 2009). For «originals» this figure has dropped from 56,6 days in 2009 to 26.6 days in 2014. The mean time elapsed from manuscript reception to its on-line publication was 103 days. In 2014 the collaboration with the working groups from the Internal Medicine Spanish Foundation (FEMI) has reported 11 published manuscripts. In July 2014 we were informed that the Journal Citation Reports gave Rev Clin Esp an Impact Factor of 1,314 (year 2013). This Impact Factor without self-citations would have been 0.705 (in 2009 the global impact factor was 0,584). With the Editorial Committee farewell we welcome the new editorial team and we sincerely thank the SEMI Steering Committee, our colleagues, journal officers, reviewers, readers and authors that since 2009 have trusted on our editorial work.

  4. EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Corkum, Paul

    2011-01-01

    As a journal that reports advances in atomic, molecular and optical science (AMO), Journal of Physics B: Atomic, Molecular and Optical Physics (J. Phys. B) provides the AMO research community with three unique fora: topical reviews, tutorials and special issues. Developed under the leadership of editor Jan Michael Rost and his Editorial Board, these sections have cemented J. Phys. B's reputation as a major journal showcasing the AMO community's advances. For me, an AMO scientist, it is therefore a special pleasure to be entrusted with continuing the tradition of excellence established by Jan Michael and the Editorial Board. I intend to build on this foundation by ensuring that the journal makes full use of these tools. Topical reviews: a unique focus When J. Phys. B becomes the first journal you turn to for initial reviews about important emerging areas in your field, we as an Editorial Board will have succeeded. To us, a topical review is different from a traditional review—a topical review focuses on emerging sub-fields of AMO physics. Its function is to alert and educate our readers about emerging opportunities. Topical reviews can also serve a closely related function for readers: keeping us up-to-date with critical technologies that lie slightly outside our own fields, such as advances in free-electron lasers science, (which will surely affect our field). Our overall goal is to make your research more productive because of the topical reviews you read within the journal. Tutorials J. Phys. B tutorials are aimed at graduate students or researchers venturing into a new field. Just as in my own research group I encourage all graduate students to write their theses in a way that will be useful to both future graduate students and the larger community beyond my group, J. Phys. B has designed tutorials to fill this function on the journal scale. Thus, tutorial authors are able to write in greater depth than can be included in a paper in nature, science or in the

  5. EDITORIAL: Message from the Editor Message from the Editor

    NASA Astrophysics Data System (ADS)

    Thomas, Paul

    2012-01-01

    Board Members, Guest Editors of special editions and those referees who were already listed in the last years. The following people have been selected: Marina Becoulet, CEA Cadarache, France Russell Doerner, University of California - San Diego, USA Emiliano Fable, Max-Planck-Institut fuer Plasmaphysik, Germany Akihide Fujisawa, Kyushi University, Japan Gerardo Giruzzi, CEA Cadarache, France Grigory Kagan, LANL, USA Morten Lennholm, CCFE, UK Akinobu Matsuyama, NIFS, Japan Peter Stangeby, University of Toronto, Canada Leonid Zakharov, PPPL, USA In addition, there is a group of several hundred referees who have helped us in the past year to maintain the high scientific standard of Nuclear Fusion. At the end of this issue we give the full list of all referees for 2011. Our thanks to them! Authors The winner of the 2011 Nuclear Fusion Award is H. Urano, for the paper 'Dimensionless parameter dependence of H-mode pedestal width using hydrogen and deuterium plasmas in JT-60U' (Nucl. Fusion 48 045008). The award was presented at the Plasma Conference 2011 (Joint meeting of 28th JSPF Annual Meeting, The 29th Symposium on Plasma Processing, and Division of Plasma Physics, 2011 Autumn Meeting of The Physical Society of Japan). This is the sixth year that the International Atomic Energy Agency (IAEA) has awarded an annual prize to honour exceptional work published in Nuclear Fusion. IOP Publishing has generously made a contribution of $2500 to the award. The Nuclear Fusion Electronic Archive The journal's electronic archive has been online since the beginning of the year. The archive has been a roaring success and has contributed to the nearly 300 000 downloads of journal papers in 2011. The archive can be accessed via http://iopscience.iop.org/0029-5515/page/Archive. It has direct links to 16 landmark papers, from authors such as Artsimovich and Mercier. The Nuclear Fusion office and IOP Publishing Just as the journal depends on the authors and referees, so its success is also

  6. STS-86 Pilot Michael Bloomfield suits up

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-86 Pilot Michael J. Bloomfield relaxes for a moment while donning his launch and entry suit with the assistance of a suit technician in the Operations and Checkout Building. This will be Bloomfields first spaceflight. He and the six other crew members will depart shortly for Launch Pad 39A, where the Space Shuttle Atlantis awaits liftoff on a 10-day mission slated to be the seventh docking of the Space Shuttle with the Russian Space Station Mir.

  7. [Report of the editors, 2013].

    PubMed

    García Puig, J; Gaspar Alonso-Vega, G; Ríos Blanco, J J

    2014-01-01

    The editors of Revista Clínica Española(Rev Clin Esp) inform on their editorial activity during the last 12 months: (a) objectives and attainments, (b) editorial activity, and (c) objectives for 2014. In 2013 the most relevant modification concerning the editorial activity has been the translation into English of the 5 manuscripts with abstract contained in each issue (http://www.revclinesp.es/). From the first January to the 30th September 2013 we received 458 manuscripts (50.9 manuscripts per month), a similar figure to that obtained in 2012 (51.1 manuscripts per month). The acceptance rate of the 443 manuscripts whose editorial process has been concluded was 23.7% (originals, 11.8%). We asked for 253 revisions to 186 reviewers and we received 74.4% revisions in less than 2 weeks (10.9 days). The mean time to adopt an editorial decision for all manuscripts («accepted»/«rejected») has been 20,3 (half than in 2009). For «originals» this figure has dropped from 56.6 days in 2009 to 22.5 days in 2013. The mean time elapsed from manuscript reception to its on-line publication was 94.8 days in 2013 (110.5 in 2012 and 155.8 in 2011). In 2013 the collaboration with the working groups from the Internal Medicine Spanish Foundation has reported 17 published manuscripts. In 2013 we were informed that the Journal Citation Reports excluded Rev Clin Esp from its impact factor journal list due to its elevated self-citations. We have taken a number of actions to reduce self-citations and we expect to be a minority in 2014. Some other data concerning the editorial policy are encouraging. In this sense, manuscript citation to Rev Clin Esp published articles has seen a substantial increase from 19% in 2008 to 29% in 2012. We work to achieve the digitalization of Rev Clin Esp from 1940 to 1999 (the journal is already digitalized since 2000). The continuous renewal of the journal sections and the working groups collaboration are necessary elements to make our journal, each day

  8. [Report of the editors, 2013].

    PubMed

    García Puig, J; Gaspar Alonso-Vega, G; Ríos Blanco, J J

    2014-01-01

    The editors of Revista Clínica Española(Rev Clin Esp) inform on their editorial activity during the last 12 months: (a) objectives and attainments, (b) editorial activity, and (c) objectives for 2014. In 2013 the most relevant modification concerning the editorial activity has been the translation into English of the 5 manuscripts with abstract contained in each issue (http://www.revclinesp.es/). From the first January to the 30th September 2013 we received 458 manuscripts (50.9 manuscripts per month), a similar figure to that obtained in 2012 (51.1 manuscripts per month). The acceptance rate of the 443 manuscripts whose editorial process has been concluded was 23.7% (originals, 11.8%). We asked for 253 revisions to 186 reviewers and we received 74.4% revisions in less than 2 weeks (10.9 days). The mean time to adopt an editorial decision for all manuscripts («accepted»/«rejected») has been 20,3 (half than in 2009). For «originals» this figure has dropped from 56.6 days in 2009 to 22.5 days in 2013. The mean time elapsed from manuscript reception to its on-line publication was 94.8 days in 2013 (110.5 in 2012 and 155.8 in 2011). In 2013 the collaboration with the working groups from the Internal Medicine Spanish Foundation has reported 17 published manuscripts. In 2013 we were informed that the Journal Citation Reports excluded Rev Clin Esp from its impact factor journal list due to its elevated self-citations. We have taken a number of actions to reduce self-citations and we expect to be a minority in 2014. Some other data concerning the editorial policy are encouraging. In this sense, manuscript citation to Rev Clin Esp published articles has seen a substantial increase from 19% in 2008 to 29% in 2012. We work to achieve the digitalization of Rev Clin Esp from 1940 to 1999 (the journal is already digitalized since 2000). The continuous renewal of the journal sections and the working groups collaboration are necessary elements to make our journal, each day

  9. Report of the editors, 2014.

    PubMed

    García Puig, J; Gaspar Alonso-Vega, G; Ríos Blanco, J J

    2015-01-01

    The editors of Revista Clínica Española(Rev Clin Esp) inform on their editorial activity during the last 12 months: (a) Objectives and attainments in 2014, (b) Editorial activity, 2014, and (c) 2013 impact factor. In 2014 we achieved the 5 planned objectives. We have published the 9 programmed issues and 103% of the planned papers according to the usual fixed sections. We emphasize the publication of 29 editorials, 21 of which are signed by prestigious foreign authors. From the first January to the 30th September 2014 we received 421 manuscripts (46.8 manuscripts per month), a slight lower figure to that obtained in 2013 (50.9 manuscripts per month). The acceptance rate of the 404 manuscripts whose editorial process has been concluded was 32.3% (originals, 22.4%). We asked for 315 revisions to 240 reviewers and we received 53.3% revisions in less than two weeks (10.4 days). The mean time to adopt an editorial decision for all manuscripts («accepted»/«rejected») has been 18,3 (less than half than in 2009). For «originals» this figure has dropped from 56,6 days in 2009 to 26.6 days in 2014. The mean time elapsed from manuscript reception to its on-line publication was 103 days. In 2014 the collaboration with the working groups from the Internal Medicine Spanish Foundation (FEMI) has reported 11 published manuscripts. In July 2014 we were informed that the Journal Citation Reports gave Rev Clin Esp an Impact Factor of 1,314 (year 2013). This Impact Factor without self-citations would have been 0.705 (in 2009 the global impact factor was 0,584). With the Editorial Committee farewell we welcome the new editorial team and we sincerely thank the SEMI Steering Committee, our colleagues, journal officers, reviewers, readers and authors that since 2009 have trusted on our editorial work. PMID:25441406

  10. EDITORIAL: Letter from the Editor Letter from the Editor

    NASA Astrophysics Data System (ADS)

    Hauptmann, Peter

    2011-01-01

    Dear authors and reviewers of articles for Measurement Science and Technology, I would like to thank all those who have published papers with us in 2010, and special thanks go to those of you who have kindly reviewed articles for the journal. I would also like to take this opportunity to update you on some of the developments on the journal and look ahead to 2011. As many of you are no doubt aware, our impact factor (a measure of the average number of times recent papers are referred to by others) is currently 1.317. This is often taken as an indication of the quality and relevance of recently published research, and although as readers we develop our own instinct for journals of high quality, it is gratifying as an Editor to see the data from an independent organization (Thomson ISI) agreeing with my own assessment. Measurement Science and Technology is a journal with a broad scope covering new measurement techniques in all fields of science and engineering. I therefore find it particularly enjoyable to read summaries of recent research in our strong topical review programme as these cover many varied topics of interest. In 2010 several interesting articles by international leaders in their field were published, for example: Single-photon generation and detection, by G S Buller and R J Collins of Heriot-Watt University [1]. Fluorescence lifetime imaging microscopy in life sciences, by Jan Willem Borst and Antonie J W G Visser, from the Microspectroscopy Centre of Wageningen University [2]. Biological and chemical sensors for cancer diagnosis, by Elfriede Simon of Siemens AG [3]. I hope that these articles, and the others published in 2010 and now in 2011, will provide a useful overview for our readers, and be helpful to new researchers. When speaking to young researchers I am particularly aware that having their articles published in a timely fashion is important, and I am pleased that our publication times are highly competitive, with most authors receiving a

  11. AGU Publications Volunteers Feted At Elegant Editors' Evening

    NASA Astrophysics Data System (ADS)

    Panning, Jeanette

    2013-01-01

    The 2012 Fall Meeting Editors' Evening, held at the City Club of San Francisco, was hosted by the Publications Committee and is the premier social event for editors and associate editors attending the Fall Meeting. The evening commenced with a welcome from Carol Finn, incoming AGU president, in which she expressed her thanks to the editors and associate editors for volunteering their time to benefit AGU.

  12. [The Chilean Association of Biomedical Journal Editors].

    PubMed

    Reyes, H

    2001-01-01

    On September 29th, 2000, The Chilean Association of Biomedical Journal Editors was founded, sponsored by the "Comisión Nacional de Investigación Científica y Tecnológica (CONICYT)" (the Governmental Agency promoting and funding scientific research and technological development in Chile) and the "Sociedad Médica de Santiago" (Chilean Society of Internal Medicine). The Association adopted the goals of the World Association of Medical Editors (WAME) and therefore it will foster "cooperation and communication among Editors of Chilean biomedical journals; to improve editorial standards, to promote professionalism in medical editing through education, self-criticism and self-regulation; and to encourage research on the principles and practice of medical editing". Twenty nine journals covering a closely similar number of different biomedical sciences, medical specialties, veterinary, dentistry and nursing, became Founding Members of the Association. A Governing Board was elected: President: Humberto Reyes, M.D. (Editor, Revista Médica de Chile); Vice-President: Mariano del Sol, M.D. (Editor, Revista Chilena de Anatomía); Secretary: Anna María Prat (CONICYT); Councilors: Manuel Krauskopff, Ph.D. (Editor, Biological Research) and Maritza Rahal, M.D. (Editor, Revista de Otorrinolaringología y Cirugía de Cabeza y Cuello). The Association will organize a Symposium on Biomedical Journal Editing and will spread information stimulating Chilean biomedical journals to become indexed in international databases and in SciELO-Chile, the main Chilean scientific website (www.scielo.cl).

  13. Michael Fordham and the Journal of Analytical Psychology: the view from Hangman's Hill.

    PubMed

    Urban, Elizabeth

    2015-09-01

    This short paper was presented to a conference in honour of the 60(th) year of the JAP and was one of others that acknowledged the contribution of Michael Fordham. The subtitle refers to the paper's overview of Fordham's published oeuvre and the particular place of the Journal of Analytical Psychology, for which he was the founding editor. Fordham's contribution to a Jungian-based model of development is discussed, with reference to his papers in the British Journal of Medical Psychology. The paper notes miscellaneous pieces from Fordham's commentaries, obituaries, papers and reviews which capture not only the development of Fordham as a thinker but also his character. There is discussion of his reviews of Melanie Klein's Envy and Gratitude and manuscripts by Erich Neumann. A reminiscence of Fordham as supervisor is recounted.

  14. Michael Fordham and the Journal of Analytical Psychology: the view from Hangman's Hill.

    PubMed

    Urban, Elizabeth

    2015-09-01

    This short paper was presented to a conference in honour of the 60(th) year of the JAP and was one of others that acknowledged the contribution of Michael Fordham. The subtitle refers to the paper's overview of Fordham's published oeuvre and the particular place of the Journal of Analytical Psychology, for which he was the founding editor. Fordham's contribution to a Jungian-based model of development is discussed, with reference to his papers in the British Journal of Medical Psychology. The paper notes miscellaneous pieces from Fordham's commentaries, obituaries, papers and reviews which capture not only the development of Fordham as a thinker but also his character. There is discussion of his reviews of Melanie Klein's Envy and Gratitude and manuscripts by Erich Neumann. A reminiscence of Fordham as supervisor is recounted. PMID:26274849

  15. Obituary: Michael James Ledlow, 1964-2004

    NASA Astrophysics Data System (ADS)

    Puxley, Philip John; Grashuis, Randon M.

    2004-12-01

    Michael James Ledlow died on 5 June 2004 from a large, unsuspected brain tumor. Since 2000 he had been on the scientific staff of the Gemini Observatory in La Serena, Chile, initially as a Science Fellow and then as a tenure-track astronomer. Michael was born in Bartlesville, Oklahoma on 1 October 1964 to Jerry and Sharon Ledlow. He obtained his Bachelor Degree in astrophysics at the University of Oklahoma in 1987 and attended the University of New Mexico for his graduate work, obtaining his PhD while studying Galaxy Clusters under Frazer Owen in 1994. From 1995-1997 Michael held a postdoctoral position with Jack Burns at New Mexico State University where he used various astronomical facilities including the VLA and Apache Point Observatory to study distant galaxies. From 1998-2000 Michael rejoined the Physics and Astronomy Department at the University of New Mexico where he was a visiting professor until he moved on to Gemini. At the Gemini Observatory, Mike shared in the excitement, hard work and many long days and nights associated with bringing on-line a major new astronomical facility and its instrumentation. Following its commissioning he assisted visiting observers, supported and took data for many more remote users via the queue system, and for each he showed the same care and attention to detail evident in his own research to ensure that all got the best possible data. His research concentrated on the radio and optical properties of galaxy clusters, especially rich Abell clusters such as A2125, on luminous radio galaxies, including the detection of a powerful double radio source in the "wrong sort of galaxy," the spiral system 0313-192, and on EROs (extremely red objects), dusty galaxies barely detectable at optical wavelengths. Michael thoroughly enjoyed living in Chile and enthusiastically immersed himself in the culture of his surroundings. He and his family were actively involved with the International English Spanish Association in La Serena. He had a

  16. EDITORIAL: Letter from the Editor

    NASA Astrophysics Data System (ADS)

    Hauptmann, Peter

    2008-01-01

    Dear authors and reviewers of articles for Measurement Science and Technology, I would like to thank all those who have published papers with us in 2007, and special thanks go to those of you who have kindly reviewed articles for the journal this year. I would also like to take this opportunity to update you on some of the developments on the journal. As many of you are no doubt aware, our latest impact factor (a measure of the average number of times recent papers are referred to by others) has risen to 1.228. This is often taken as an indication of the quality and relevance of recently published research, and although as readers we develop our own instinct for journals of high quality, it is gratifying as an Editor to see the data from an independent organization agreeing with my own assessment. The popularity of the journal amongst authors and readers has prompted us to introduce a new subject classification for articles, to make it easier for readers to find articles of interest. The eight subject categories are: Measurement theory and practical developments (e.g. precision measurements, metrology, new measurement principles, signal processing techniques, theory of measurement, calibration); Sensors and sensing systems (based on physical, chemical or biological principles; micro- and nano-scale systems; sensors for physical, chemical and biological quantities); Optical and laser based techniques (e.g. fibre optics, interferometry, etc); Fluid mechanics measurements (e.g. fluid flow, velocimetry, particle sizing, etc); Imaging techniques (e.g. tomography, microscopy, holography, THz, etc); Spectroscopy (e.g. optical, acoustic, dielectric, MS, NMR, ESR, IR, UV-VIS, fluorescence, PCS, x-ray, etc); New and improved techniques for materials evaluation (e.g. non-destructive testing and evaluation, structural measurements); Novel instrumentation. We kindly ask you to assign your paper to a category when you send it to the journal. In order to maintain our rapid

  17. EDITORIAL: Message from the Editor

    NASA Astrophysics Data System (ADS)

    Thomas, Paul

    2008-01-01

    To begin, I would like to wish our readers, authors, referees and Board of Editors a successful and happy 2008 and thank them for their contributions to Nuclear Fusion in 2007. I took over the editorship of Nuclear Fusion in January, and the year has been one in which the community as a whole has been busier than ever with a variety of duties associated with the ITER project. It was with pride that we published the Progress in the ITER Physics Basis in the June issue of the journal (stacks.iop.org/NF/47/i=6). The task undertaken by the coordinators, authors and referees was a daunting one but one which led to an outstandingly successful issue. The response from readers has been phenomenal and there were in the region of 10 000 downloads of papers in the first month following publication. Looking to 2008 and beyond, the journal will endeavour to continue to support the work of the fusion community. Refereeing As we have done since January 2005, we would like to thank our top ten most loyal referees who have helped the journal with its double-referee peer-review procedure in the past year. At the Nuclear Fusion Editorial Office we are fully aware of the load we put on the shoulders of our referees. At the end of 2004 the Editorial Board decided that a gesture of gratitude should be made to our most loyal referees. We offer them a personal subscription to Nuclear Fusion with electronic access for one year, free of charge. To select the top referees we have adopted the criterion that a researcher should have acted as a referee or adjudicator for at least three different manuscripts during the period from summer 2006 to the end of 2007. We have excluded our Board members and those referees who were already listed in the top ten in the last two years. According to our records the following people met this criterion. Congratulations and many, many thanks! H.L. Berk (Texas University, USA) J.S. DeGrassie (GAT, USA) C. Deutsch (Paris University, France) N. Hayashi (JAEA

  18. EDITORIAL: Letter from the Editor

    NASA Astrophysics Data System (ADS)

    Hauptmann, Peter

    2009-01-01

    Marella de Angelis and her colleagues on precision gravimetry using atomic sensors and from Dr Peter Becker on determination of the Avogadro constant via enriched silicon-28. I recommend setting up a free e-mail alert so that you can read them as soon as they are published! As many of you are already aware, our impact factor (a measure of the average number of times recent papers are referred to by others) has risen again to 1.297. This is often taken as an indication of the quality and relevance of recently published research, and although as readers we develop our own instinct for journals of high quality, it is gratifying as an Editor to see the data from an independent organization (Thomson ISI) agreeing with my own assessment. Of course the publication of high quality articles in the journal is dependent both on you the authors who trust us with the publication of your best work and on our referees and Editorial Board Members who we depend on to maintain the high standards you have grown to expect. I must also thank our referees for their rapid response when asked to review papers for Measurement Science and Technology. On average, authors receive a decision on their article in 45 days. Therefore I would like to end this message by saying thank you again to all those who have contributed to our success in the past year, and wish you all the best for a successful 2009!

  19. EDITORIAL: Letter from the Editor

    NASA Astrophysics Data System (ADS)

    Hauptmann, Peter

    2006-12-01

    Dear authors and reviewers of articles for Measurement Science and Technology, I would like to thank all those who have published papers with us in 2006, and special thanks go to those of you who have kindly reviewed articles for the journal this year. I would also like to take this opportunity to update you on some of the developments on the journal this year. As many of you are no doubt aware our impact factor (a measure of the average number of times recent papers are referred to by others) has remained above 1 for the second year in a row. This is often taken as an indication of the quality and relevance of recently published research, and although as readers we develop our own instinct for journals of high quality, it is gratifying as an Editor to see the data from an independent organization agreeing with my own assessment. This year we have welcomed several new faces to our Editorial Board and International Advisory Board. We are delighted to welcome Professor Hirofumi Yamada of the University of Kyoto as a representative from Japan. From China we have been joined by Professor Xuzong Chen of Peking University and Professor Zhiyi Wei of Chinese Academy of Sciences, Beijing. Professor Ivan Marusic from University of Minnesota and Dr Paul Williams of the National Institute of Standards and Technology in Boulder have joined as North American representatives. As usual you will be able to submit your articles through them or direct to the Editorial Office in Bristol, UK. As part of our ongoing initiative to give our authors' work the highest visibility, all articles are freely available online for 30 days from the date of publication, allowing all researchers to read and view the latest research as soon as it is published, and this year there have been many interesting articles to read! As regular readers are aware, Measurement Science and Technology publishes special issues and features, which highlight an area of current interest. This year's topics included

  20. Open Simulation Laboratories [Guest editors' introduction

    SciTech Connect

    Alexander, Francis J.; Meneveau, Charles

    2015-09-01

    The introduction for the special issue on open simulation laboratories, the guest editors describe how OSLs will become more common as their potential is better understood and they begin providing access to valuable datasets to much larger segments of the scientific community. Moreover, new analysis tools and ways to do science will inevitably develop as a result.

  1. A Visual Editor in Java for View

    NASA Technical Reports Server (NTRS)

    Stansifer, Ryan

    2000-01-01

    In this project we continued the development of a visual editor in the Java programming language to create screens on which to display real-time data. The data comes from the numerous systems monitoring the operation of the space shuttle while on the ground and in space, and from the many tests of subsystems. The data can be displayed on any computer platform running a Java-enabled World Wide Web (WWW) browser and connected to the Internet. Previously a special-purpose program bad been written to display data on emulations of character-based display screens used for many years at NASA. The goal now is to display bit-mapped screens created by a visual editor. We report here on the visual editor that creates the display screens. This project continues the work we bad done previously. Previously we had followed the design of the 'beanbox,' a prototype visual editor created by Sun Microsystems. We abandoned this approach and implemented a prototype using a more direct approach. In addition, our prototype is based on newly released Java 2 graphical user interface (GUI) libraries. The result has been a visually more appealing appearance and a more robust application.

  2. Are Editors Out of the Tenure Process?

    ERIC Educational Resources Information Center

    Howard, Jennifer

    2007-01-01

    University presses have complained for years that tenure committees unfairly expect their editors to be arbiters of what counts as tenure-worthy work. At the same time, the presses have been caught in a business-side squeeze between dwindling sales (and shrinking subsidies) and the ever-greater pressure on scholars to publish. In this article, the…

  3. Michael Faraday and his contribution to anesthesia.

    PubMed

    Bergman, N A

    1992-10-01

    Michael Faraday (1791-1867) was a protégé of Humphry Davy. He became one of Davy's successors as Professor of Chemistry at the Royal Institution of Great Britain. Of Faraday's many brilliant discoveries in chemistry and physics, probably the best remembered today is his work on electromagnetic induction. Faraday's contribution to introduction of anesthesia was his published announcement in 1818 that inhalation of the vapor of ether produced the same effects on mentation and consciousness as the breathing of nitrous oxide. He most likely became familiar with the central nervous system effects of nitrous oxide through his association with Davy, an avid user of the gas. Sulfuric ether was a common, convenient, cheap, and easily available substance, in contrast to nitrous oxide, which required expensive, cumbersome, and probably not widely available apparatus for its production and administration. The capability for inhaling intoxicating vapors eventually became commonly available with the use of ether instead of the gas. The first surgical anesthetics were a consequence of the resulting student "ether frolics." The 1818 announcement on breathing ether vapor was published anonymously; however, notations in Faraday's handwriting in some of his personal books clearly establish Michael Faraday as the author of this brief communication. PMID:1416178

  4. Michael Faraday and his contribution to anesthesia.

    PubMed

    Bergman, N A

    1992-10-01

    Michael Faraday (1791-1867) was a protégé of Humphry Davy. He became one of Davy's successors as Professor of Chemistry at the Royal Institution of Great Britain. Of Faraday's many brilliant discoveries in chemistry and physics, probably the best remembered today is his work on electromagnetic induction. Faraday's contribution to introduction of anesthesia was his published announcement in 1818 that inhalation of the vapor of ether produced the same effects on mentation and consciousness as the breathing of nitrous oxide. He most likely became familiar with the central nervous system effects of nitrous oxide through his association with Davy, an avid user of the gas. Sulfuric ether was a common, convenient, cheap, and easily available substance, in contrast to nitrous oxide, which required expensive, cumbersome, and probably not widely available apparatus for its production and administration. The capability for inhaling intoxicating vapors eventually became commonly available with the use of ether instead of the gas. The first surgical anesthetics were a consequence of the resulting student "ether frolics." The 1818 announcement on breathing ether vapor was published anonymously; however, notations in Faraday's handwriting in some of his personal books clearly establish Michael Faraday as the author of this brief communication.

  5. Organocatalytic enantioselective Michael-Michael-Michael-aldol condensation reactions: control of five stereocenters in a quadruple-cascade asymmetric synthesis of highly functionalized hexahydrophenanthrenes.

    PubMed

    Raja, Arun; Hong, Bor-Cherng; Lee, Gene-Hsiang

    2014-11-01

    A cascade organocatalysis has been developed for the enantioselective synthesis of a highly functionalized hexahydrophenanthrene-2-carbaldehyde containing five contiguous stereogenic centers with high diastereoselectivity and high enantioselectivity (>99% ee). The one-pot method comprises a cascade of organocatalytic Michael-Michael-Michael-aldol reactions of 2-methyl-1,5-dinitro-3-((E)-2-nitrovinyl)benzene and α,β-unsaturated aldehydes (e.g., cinnamaldehyde). The structure and absolute configuration of a product were confirmed by X-ray analysis of an appropriate derivative.

  6. OPM Scheme Editor 2: A graphical editor for specifying object-protocol structures

    SciTech Connect

    Chen, I-Min A.; Markowitz, V.M.; Pang, F.; Ben-Shachar, O.

    1993-07-01

    This document describes an X-window based Schema Editor for the Object-Protocol Model (OPM). OPM is a data model that supports the specification of complex object and protocol classes. objects and protocols are qualified in OPM by attributes that are defined over (associated with) value classes. Connections of object and protocol classes are expressed in OPM via attributes. OPM supports the specification (expansion) of protocols in terms of alternative and sequences of component (sub) protocols. The OPM Schema Editor allows specifying, displaying, modifying, and browsing through OPM schemas. The OPM Schema Editor generates an output file that can be used as input to an OPM schema translation tool that maps OPM schemas into definitions for relational database management systems. The OPM Schema Editor was implemented using C++ and the X11 based Motif toolkit, on Sun SPARCstation under Sun Unix OS 4.1. This document consists of the following parts: (1) A tutorial consisting of seven introductory lessons for the OPM Schema Editor. (2) A reference manual describing all the windows and functions of the OPM Schema Editor. (3) An appendix with an overview of OPM.

  7. From the Board of Editors: on Plagiarism

    NASA Astrophysics Data System (ADS)

    2005-04-01

    From the Board of Editors: on Plagiarism

    Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission: Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur

  8. Editor and Student Views on the Censorship Game.

    ERIC Educational Resources Information Center

    Raburn, Josephine

    Out of 200 newspaper editors randomly selected from a directory, 64 responded to a questionnaire eliciting their opinions on the subject materials most often censored by groups in the United States. The editors' responses were compared to those of 121 freshmen at Cameron University (Oklahoma). A majority of the editors supported the First…

  9. Editors' Attitudes toward Functions of the Community Press.

    ERIC Educational Resources Information Center

    Flocke, Elizabeth Lynne

    A study focused on isolating the differences in perceptions community newspaper editors have about the functions of their newspapers, and determining how those attitudes affect the editors' definition of news and, ultimately, the content of the newspapers. The study hypothesized (1) that the perceptions community newspaper editors have toward the…

  10. Language and Intercultural Education: An Interview with Michael Byram

    ERIC Educational Resources Information Center

    Porto, Melina

    2013-01-01

    This article reports an interview with Michael Byram, Professor Emeritus, University of Durham in the United Kingdom, during his visit to Argentina in September 2011. Michael Byram is one of the main international referents in intercultural education. The interview addresses issues such as language education, intercultural and citizenship…

  11. Doing It All: Michael Sullivan--Weeks Public Library, NH

    ERIC Educational Resources Information Center

    Library Journal, 2005

    2005-01-01

    Michael Sullivan is a juggler--not a metaphorical one, a real one. He's also a library director, storyteller, competitive chess player, poet, speaker, and former children's librarian who continues to work with the kids in his community. This article summarizes the accomplishments and work of Michael Sullivan.

  12. 76 FR 10352 - Keyser, Michael J.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-02-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Keyser, Michael J.; Notice of Filing Take notice that on February 15, 2011, Michael J. Keyser submitted for filing, an application for authority to hold interlocking...

  13. Michael J. Meaney: Award for Distinguished Scientific Contributions

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents Michael J. Meaney as one of the winners of the American Psychological Association's Award for Distinguished Scientific Contributions (2012). Michael J. Meaney has taken the phenomenon of "handling" of newborn rats and opened a new area of investigation that has given new meaning to epigenetics via his work demonstrating transgenerational…

  14. Michael Young and the Curriculum Field in South Africa

    ERIC Educational Resources Information Center

    Hoadley, Ursula

    2015-01-01

    The paper addresses the question of what we should make of Michael Young's recent work with respect to curriculum theory by considering the particular case of South African curriculum reform. The paper thus traces two trajectories: the evolution of Michael Young's ideas over time and South African curriculum reform in the post-apartheid period.…

  15. Michael Naranjo, The Story of an American Indian.

    ERIC Educational Resources Information Center

    Nelson, Mary Carroll

    Michael Naranjo is a Pueblo Indian who, after much searching, has become a talented sculptor. The son of a Baptist minister, Michael grew up observing nature and exploring the countryside around Santa Clara (New Mexico), his birthplace. When he was nine, his family moved to Taos, where he watched the ceremonies of the Taos Pueblos with…

  16. Michael Faraday's Contributions to Archaeological Chemistry.

    PubMed

    Moshenska, Gabriel

    2015-08-01

    The analysis of ancient artefacts is a long but largely neglected thread within the histories of archaeology and chemistry. This paper examines Michael Faraday's contributions to this nascent field, drawing on his published correspondence and the works of his antiquarian collaborators, and focusing in particular on his analyses of Romano-British and ancient Egyptian artefacts. Faraday examined the materials used in ancient Egyptian mummification, and provided the first proof of the use of lead glazes on Roman ceramics. Beginning with an assessment of Faraday's personal interests and early work on antiquities with Humphry Davy, this paper critically examines the historiography of archaeological chemistry and attempts to place Faraday's work within its institutional, intellectual, and economic contexts. PMID:26307911

  17. Michael Maier--nine newly discovered letters.

    PubMed

    Lenke, Nils; Roudet, Nicolas; Tilton, Hereward

    2014-02-01

    The authors provide a transcription, translation, and evaluation of nine newly discovered letters from the alchemist Michael Maier (1568-1622) to Gebhardt Johann von Alvensleben (1576-1631), a noble landholder in the vicinity of Magdeburg. Stemming from the final year of his life, this correspondence casts new light on Maier's biography, detailing his efforts to secure patronage amid the financial crisis of the early Thirty Years' War. While his ill-fated quest to perfect potable gold continued to form the central focus of his patronage suits, Maier also offered his services in several arts that he had condemned in his printed works, namely astrology and "supernatural" magic. Remarks concerning his previously unknown acquaintance with Heinrich Khunrath call for a re-evaluation of Maier's negotiation of the discursive boundaries between Lutheran orthodoxy and Paracelsianism. The letters also reveal Maier's substantial contribution to a work previously ascribed solely to the English alchemist Francis Anthony. PMID:25241502

  18. Michael Faraday's Contributions to Archaeological Chemistry.

    PubMed

    Moshenska, Gabriel

    2015-08-01

    The analysis of ancient artefacts is a long but largely neglected thread within the histories of archaeology and chemistry. This paper examines Michael Faraday's contributions to this nascent field, drawing on his published correspondence and the works of his antiquarian collaborators, and focusing in particular on his analyses of Romano-British and ancient Egyptian artefacts. Faraday examined the materials used in ancient Egyptian mummification, and provided the first proof of the use of lead glazes on Roman ceramics. Beginning with an assessment of Faraday's personal interests and early work on antiquities with Humphry Davy, this paper critically examines the historiography of archaeological chemistry and attempts to place Faraday's work within its institutional, intellectual, and economic contexts.

  19. Michael Maier--nine newly discovered letters.

    PubMed

    Lenke, Nils; Roudet, Nicolas; Tilton, Hereward

    2014-02-01

    The authors provide a transcription, translation, and evaluation of nine newly discovered letters from the alchemist Michael Maier (1568-1622) to Gebhardt Johann von Alvensleben (1576-1631), a noble landholder in the vicinity of Magdeburg. Stemming from the final year of his life, this correspondence casts new light on Maier's biography, detailing his efforts to secure patronage amid the financial crisis of the early Thirty Years' War. While his ill-fated quest to perfect potable gold continued to form the central focus of his patronage suits, Maier also offered his services in several arts that he had condemned in his printed works, namely astrology and "supernatural" magic. Remarks concerning his previously unknown acquaintance with Heinrich Khunrath call for a re-evaluation of Maier's negotiation of the discursive boundaries between Lutheran orthodoxy and Paracelsianism. The letters also reveal Maier's substantial contribution to a work previously ascribed solely to the English alchemist Francis Anthony.

  20. STS-97 Crew Interviews: Michael J. Bloomfield

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Live footage of a preflight interview with Pilot Michael J. Bloomfield is shown. The interview addresses many different questions including why Bloomfield became interested in the space program, the events and people that influence him and ultimately led to his interest, and his vigorous training in the astronaut program. Other interesting information that this one-on-one interview discusses are the main goals of the STS-97 mission, its scheduled docking with the new International Space Station (ISS), and its delivery of the first set of U.S.-provided solar arrays, batteries, and radiators. Bloomfield briefly discusses his responsibilities during the much-anticipated docking as well as during the scheduled space-walks.

  1. STS-109 Crew Interviews: Michael J. Massimino

    NASA Technical Reports Server (NTRS)

    2002-01-01

    STS-109 Mission Specialist Michael J. Massimino is seen during a prelaunch interview. He answers questions about his inspiration to become an astronaut, his career path, and his most memorable experiences. He gives details on the mission's goals and objectives, which focus on the refurbishing of the Hubble Space Telescope, and his role in the mission. He explains the plans for the rendezvous of the Columbia Orbiter with the Hubble Space Telescope. He provides details and timelines for each of the planned Extravehicular Activities (EVAs), which include replacing the solar arrays, changing the Power Control Unit, installing the Advanced Camera for Surveys (ACS), and installing a new Cryocooler for the Near Infrared Camera and Multi-Object Spectrometer (NICMOS). He also describes the break-out plan in place for these spacewalks. The interview ends with Massimino explaining the details of a late addition to the mission's tasks, which is to replace a reaction wheel on the Hubble Space Telescope.

  2. Evolutionary theory in letters to the editor.

    PubMed

    Silva, Eric Orion; Lowe, Clayton Cory

    2015-05-01

    This research note presents the results of a content analysis of 234 letters to the editors that discuss evolutionary theory and were published in American newspapers. We find that letters to the editor both support and hinder the cause of teaching evolutionary theory in American secondary schools. On the one hand, anti-evolutionary theory messages are marginalized in the letters section. This marginalization signals a low level of legitimacy for creationism. It might also contribute to the sense of tension that sustains creationist identities. On the other hand, relatively few letters explicitly note the fact that scientists or the scientific community accept evolution. Interestingly, the obscuration of the scientific community's support for evolutionary theory occurs both in letters supporting and opposing evolutionary theory.

  3. Evolutionary theory in letters to the editor.

    PubMed

    Silva, Eric Orion; Lowe, Clayton Cory

    2015-05-01

    This research note presents the results of a content analysis of 234 letters to the editors that discuss evolutionary theory and were published in American newspapers. We find that letters to the editor both support and hinder the cause of teaching evolutionary theory in American secondary schools. On the one hand, anti-evolutionary theory messages are marginalized in the letters section. This marginalization signals a low level of legitimacy for creationism. It might also contribute to the sense of tension that sustains creationist identities. On the other hand, relatively few letters explicitly note the fact that scientists or the scientific community accept evolution. Interestingly, the obscuration of the scientific community's support for evolutionary theory occurs both in letters supporting and opposing evolutionary theory. PMID:25540333

  4. From the Board of Editors: on Plagiarism

    NASA Astrophysics Data System (ADS)

    2005-05-01

    Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission: Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur-self-plagiarism and plagiarism from others' works. Self-plagiarism is the publication of substantially

  5. Meet the Editors: Water Resources Research

    NASA Astrophysics Data System (ADS)

    Kumar, Mohi

    2006-02-01

    On 1 January 2005, a five-member team assumed editorial responsibility for Water Resources Research (WRR). A year later the team of Brian Berkowitz, Amilcare Porporato, Thomas Torgersen, Scott Tyler, and Editor-in-Chief Marc Parlange are pleased with the successes of several changes to the journal. ``WRR is the international stage where new and emerging ideas are discussed and where the directions for scientific research in all aspects of hydrology are charted,'' explained Porporato. ``This is the reason why we have worked hard with our associate editors to attract `opinion papers,' `inspired reviews,' and, more recently, `rapid communications.''' The aim of these new paper types is to encourage discussion of water resource issues relevant to society and to quickly present new results that advance theoretical, mathematical, technological, and experimental observations, Porporato said.

  6. New Editors Appointed for Sections of Journal of Geophysical Research

    NASA Astrophysics Data System (ADS)

    2009-04-01

    New editors have been appointed for the Atmospheres, Biogeosciences, and Oceans sections of the Journal of Geophysical Research (JGR). Joost de Gouw (NOAA, Boulder, Colo.) and Renyi Zhang (Texas A&M, College Station) are filling the vacancies of retiring Atmospheres section editors John Austin and Jose Fuentes. De Gouw and Zhang join the continuing editors Steven Ghan and Yinon Rudich. Sara Pryor (Indiana University, Bloomington) is joining the Atmospheres section editorial board as an associate editor now; she will transition to editor in January 2010.

  7. Ethical responsibilities of editors, reviewers, and authors.

    PubMed

    Cowell, H R

    2000-09-01

    Scientific misconduct, which is neither new nor unique, is prevalent in the medical literature. Although fabrication of data obviously is unethical, and although ethical rules of conduct for certain aspects of medical studies, such as informed consent, are theoretically accepted worldwide, numerous authors do not adhere to ethical rules of conduct. Ethically, the editor is responsible, as a gatekeeper, for ensuring that material to be published is accurate and valid. Thus, the editor's main responsibility is to the reader. Nonetheless, the editor also must serve the author by selecting unbiased reviewers and by providing the assurance that material will be selected for publication based solely on the scientific quality of the material. Peer reviewers are obligated to maintain a posture of confidentiality throughout the review process. Authors are responsible for adequate planning before undertaking a study, and for safeguarding patients' rights during the study. The author must read all cited references completely, strive for accuracy, and be certain that the material reported is valid, because it will be used in the treatment of patients. Hopefully, awareness of the ethical problems related to medical writing will provide a clearer understanding of the ethical aspects of medical writing.

  8. The editor-referee system and publication an editor's view of the process

    NASA Astrophysics Data System (ADS)

    Shore, S. N.

    2011-07-01

    This chapter explains the functioning of scientific journals from the editorial side of the process. Both the history and current functioning of scientific journals are reviewed with a particular emphasis on the evolution of the referee's role. In its current form, the evaluation of a submission is interactive between the three parties - the author(s), editors, and reviewers. The editors serve as the mediators and final evaluators, seeking advice from one or more contacted experts who are in the special position of evaluating the science, presentation, and significance of the work. The chapter explains how this proceeds, and its advantages, pitfalls, and criteria - scientific, archival, and ethical - and how these have evolved historically and consensually. Since referees and editors are also authors, the symbiosis of the process is one of its strengths, since all participants exchange roles.

  9. From the Board of Editors: on Plagiarism

    NASA Astrophysics Data System (ADS)

    2005-04-01

    From the Board of Editors: on Plagiarism

    Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission: Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur

  10. Two papers by Michael Fordham (d.1995).

    PubMed

    Astor, James

    2010-11-01

    The Journal has decided to publish a selection of previously unpublished papers from the Michael Fordham archives, which are being prepared for publication by James Astor and Elizabeth Urban, and of which the two papers published here are the first, both dating from the 1950s. 'Analyst and Priest' seems to be addressed to an audience of mainly religious people who are interested in the relation between psychology and religion and to whom Fordham is introducing some basic Jungian concepts and ways of thinking. The analyst in this lecture is the advocate of a new science, the priest an established figure with a role in society and rituals to perform. As the paper progresses he refines the differences between priest and analyst in terms of individual development versus a philosophy of life. The paper ends with a plea for co-operation between priest and analyst. 'Analyst and Scientist' was a radio talk given in 1956. In this paper Fordham makes the case for paying attention to the irrational. He draws support from Pauli and Polanyi. His theme is to show the scientific value of the subjective. From this he describes the scientific basis for Jung's comparative method and consequently of archetypal psychology.

  11. Obituary: Michael John Klein, 1940-2005

    NASA Astrophysics Data System (ADS)

    Gulkis, Samuel

    2006-12-01

    Michael John Klein died on 14 May 2005 at home in South Pasadena, California. The cause of death was tongue cancer that metastasized to the lungs. He was a non-smoker. Mike was a passionate radio astronomer, a trusted astronomical observer, an educator and a family man. Mike was born on 19 January 1940 in Ames, Iowa, the son of Florence Marie (Graf) and Fred Michael Klein. His mother was a homemaker, and his father was a banker. Mike had two older sisters, Lois Jean (Klein) Flauher and Marilyn June (Klein) Griffin. In 1962, Mike married his high school sweetheart Barbara Dahlberg, who survives him along with their three children, Kristin Marie (Klein) Shields, Michael John Klein Jr., Timothy Joel Klein, and six grandchildren. Mike developed a love for astronomy early in his life, and credited an early morning, newspaper-delivery route that he had at age twelve, which took him outside well before sunrise. He told family members that as he walked along his route, he stared into the sky and wondered what everything was. He studied sky charts, located stars, and began to understand how the planets shifted their positions relative to the stars each day. Another big influence in Mike's life was his brother in-law, Jim Griffin. Jim helped Mike understand that his passion for science did not have to remain a hobby, but could and should become a career. Jim's encouragement led Mike to attend Iowa State University in Ames, where he earned a BS in electrical engineering in 1962. Mike then started graduate school in electrical engineering at Michigan State, but after one semester transferred to the University of Michigan, Ann Arbor, where he earned an MS (1966) and PhD (1968) in astronomy. His doctoral dissertation, under the direction of Professor Fred Haddock, was based on extensive observations of the planets and examined the physical and thermal properties of planetary atmospheres and surfaces. Mike was awarded a Resident Research Associate position at JPL by the National

  12. Two papers by Michael Fordham (d.1995).

    PubMed

    Astor, James

    2010-11-01

    The Journal has decided to publish a selection of previously unpublished papers from the Michael Fordham archives, which are being prepared for publication by James Astor and Elizabeth Urban, and of which the two papers published here are the first, both dating from the 1950s. 'Analyst and Priest' seems to be addressed to an audience of mainly religious people who are interested in the relation between psychology and religion and to whom Fordham is introducing some basic Jungian concepts and ways of thinking. The analyst in this lecture is the advocate of a new science, the priest an established figure with a role in society and rituals to perform. As the paper progresses he refines the differences between priest and analyst in terms of individual development versus a philosophy of life. The paper ends with a plea for co-operation between priest and analyst. 'Analyst and Scientist' was a radio talk given in 1956. In this paper Fordham makes the case for paying attention to the irrational. He draws support from Pauli and Polanyi. His theme is to show the scientific value of the subjective. From this he describes the scientific basis for Jung's comparative method and consequently of archetypal psychology. PMID:20961314

  13. Race, punishment, and the Michael Vick experience.

    PubMed

    Piquero, Alex R; Piquero, Nicole Leeper; Gertz, Marc; Baker, Thomas; Batton, Jason; Barnes, J C

    2011-01-01

    Objective. The relationship between race and crime has been contentious, focusing primarily on offending and incarceration patterns among minorities. There has been some limited work on public perceptions of criminal punishment, and findings show that while minorities believe in the role and rule of law, they simultaneously perceive the justice system as acting in a biased and/or unfair manner. Two limitations have stalled this literature. First, research has focused mainly on criminal punishments to the neglect of noncriminal punishments. Second, most studies have not examined whether race remains salient after considering other demographic variables or discrimination and legitimacy attitudes.Methods. Using data from 400 adults, we examine how race affects perceptions of criminal punishment and subsequent reinstatement into the National Football League in the case of Michael Vick, a star professional quarterback who pled guilty to charges of operating an illegal dog-fighting ring.Results. Findings show that whites are more likely to view Vick's punishment as too soft and that he should not be reinstated, while nonwhites had the opposite views. Race remained significant after controlling for other variables believed to be related to punishment perceptions.Conclusion. Attitudes toward both criminal punishment and NFL reinstatement vary across race such that there exists important divides in how individuals perceive the system meting out punishment and subsequently reintegrating offenders back into society. These results underscore that white and nonwhites perceive the law and its administration differently.

  14. From the Board of Editors: on Plagiarism

    NASA Astrophysics Data System (ADS)

    2005-03-01

    Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur-self-plagiarism and plagiarism from others' works. Self-plagiarism is the publication of substantially similar scientific content

  15. MPS Editor - An Integrated Sequencing Environment

    NASA Technical Reports Server (NTRS)

    Streiffert, Barbara A.; O'Reilly, Taifun; Schrock, Mitchell; Catchen, Jaime

    2010-01-01

    In today's operations environment, the teams are smaller and need to be more efficient while still ensuring the safety and success of the mission. In addition, teams often begin working on a mission in its early development phases and continue on the team through actual operations. For these reasons the operations teams want to be presented with a software environment that integrates multiple needed software applications as well as providing them with context sensitive editing support for entering commands and sequences of commands. At Jet Propulsion Laboratory, the Multi-Mission Planning and Sequencing (MPS) Editor provided by the Multi-Mission Ground Systems and Services (MGSS) supports those operational needs.

  16. Satellite Sees Hurricane Leslie and Tropical Storm Michael in Atlantic

    NASA Video Gallery

    A movie of satellite observations from Sept. 2-5, 2012, shows Leslie strengthen into a Hurricane on September 5 as it nears Bermuda, and tiny Tropical Storm Michael in the central Atlantic Ocean. T...

  17. Astronaut Michael Foale on RMS arm during EVA

    NASA Technical Reports Server (NTRS)

    1995-01-01

    Astronaut C. Michael Foale (red stripe), mission specialist, on the Remote Manipulator System (RMS) arm prepares to grab SPARTAN 204 as astronaut Bernard A. Harris Jr., payload commander, looks on during the STS-63 extravehicular activity (EVA).

  18. STS-107 M.S Michael Anderson at SPACEHAB

    NASA Technical Reports Server (NTRS)

    2000-01-01

    KENNEDY SPACE CENTER, FLA. -- At SPACEHAB, STS-107 Mission Specialist Michael Anderson (gloved, in center) gets hands-on experience with equipment. Identified as a research mission, STS-107 is scheduled for launch July 19, 2001

  19. Michael López-Alegría Profile

    NASA Video Gallery

    Meet NASA astronaut Michael López-Alegría, a veteran of four spaceflights. He has logged over 257 days in space and performed 10 spacewalks. Learn what inspired him to become such a successful astr...

  20. A Tisket, A Tasket--Out of the Editor's Basket

    NASA Astrophysics Data System (ADS)

    Williams, Kathryn R.

    2001-05-01

    In September 1940, the Journal introduced Out of the Editor's Basket for short items of interest: excerpts from letters, pamphlets, newspapers, and periodicals. By 1950, however, the Editor's Basket had evolved into a bulletin board for descriptions of new products and services, and it now contains almost exclusively press releases about recently marketed items. Now over 60 years old, the Editor's Basket still provides interesting tidbits for the Journal's broad readership.

  1. From the Board of Editors: on Plagiarism

    NASA Astrophysics Data System (ADS)

    2005-05-01

    Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission: Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur-self-plagiarism and plagiarism from others' works. Self-plagiarism is the publication of substantially

  2. From the Board of Editors: on Plagiarism

    NASA Astrophysics Data System (ADS)

    2005-04-01

    Dear Colleagues: There has been a significant increase in the number of duplicate submissions and plagiarism cases reported in all major journals, including the journals of the Optical Society of America. Duplicate submissions and plagiarism can take many forms, and all of them are violations of professional ethics, the copyright agreement that an author signs along with the submission of a paper, and OSA's published Author Guidelines. There must be a significant component of new science for a paper to be publishable. The copying of large segments of text from previously published or in-press papers with only minor cosmetic changes is not acceptable and can lead to the rejection of papers. Duplicate submission: Duplicate submission is the most common ethics violation encountered. Duplicate submission is the submission of substantially similar papers to more than one journal. There is a misperception in a small fraction of the scientific community that duplicate submission is acceptable because it sometimes takes a long time to get a paper reviewed and because one of the papers can be withdrawn at any time. This is a clear violation of professional ethics and of the copyright agreement that is signed on submission. Duplicate submission harms the whole community because editors and reviewers waste their time and in the process compound the time it takes to get a paper reviewed for all authors. In cases of duplicate submission, the Editor of the affected OSA journal will consult with the Editor of the other journal involved to determine the proper course of action. Often that action will be the rejection of both papers. Plagiarism: Plagiarism is a serious breach of ethics and is defined as the substantial replication, without attribution, of significant elements of another document already published by the same or other authors. Two types of plagiarism can occur-self-plagiarism and plagiarism from others' works. Self-plagiarism is the publication of substantially

  3. EDITORIAL: Incoming Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Lidström, Suzanne

    2012-04-01

    When Professor Anders Bárány took over as the Executive Editor of Physica Scripta, in 1986, he talked of his trepidation at having to 'dress himself' in his predecessor's 'editorial coveralls'. At that time, they had been worn by Professor Nils Robert Nilsson, a major figure in the physics community, for almost 20 years. Just one year prior to this, Professor Roger Wäppling had been recruited to the position of Subeditor in conjunction with a decision to expand the number of contributions in the field of condensed matter physics, to turn it into one of the dominant subjects in the broad-based journal. Physica Scripta had already gained a reputation for being a high quality journal with wide coverage of both experimental and theoretical physics. Interestingly, in the mid 1980s, the number of papers submitted had been growing and an impressive 250 submissions per year had been attained, with all of the manuscripts being handled in-house. Not many miles away in the town of Uppsala, a group of English students was stepping off a train on a magnificent snowy day in January to embark on their final year projects. A couple of us enjoyed ourselves so much that we stayed on afterwards as PhD students, thereby encountering the mixed pleasure of studying physics in a second language for the first time. I used to copy the notes down meticulously in Swedish, then try to work backwards with a textbook to improve my language skills. One day, returning from a particularly incomprehensible lecture on solid state physics, I showed my roommates my notes and asked if they could please explain what the lecture had been about: 'I don't know', they replied, 'but this bit is about sheep!' Meanwhile, back at Physica Scripta, the journal continued to flourish: 400 submissions were received in 1996, and the march of progress was well underway. Manuscripts could now be sent in on disks and Physica Scripta was available on the World Wide Web. Roger was appointed to manage the journal and

  4. John F. Dewey—Tectonics Editor

    NASA Astrophysics Data System (ADS)

    Richman, Barbara T.

    ‘I want the journal to acquire a reputation for very rapid, fair, and accurate reviewing,’ asserted John F. Dewey, editor-in-chief of AGU's newest journal, Tectonics. Dewey said that he will rule the bimonthly, which will begin publication in February, ‘with a bit of a rod of iron’ to ensure that Tectonics is ‘where only original and important papers are published.’‘I'm going to be very strict with reviewers,’ Dewey explained in his quick British clip. ‘If the review does not come back to me within 10 days to 2 weeks, I'll review the paper myself. I'm also going to have a system whereby, if a paper needs major surgery after being refereed, it will be rejected. Papers will have to be in virtually publishable condition before they are first submitted,’ he said.

  5. Advisers, Editors and Principals Judge First Amendment Cases.

    ERIC Educational Resources Information Center

    Broussard, E. Joseph; Blackmon, C. Robert

    1978-01-01

    A test of the knowledge of 378 high school publications advisers, editors, and principals regarding First Amendment rights revealed that advisers had the most knowledge, followed by editors and then by principals. Characteristics of the most knowledgeable advisers were then identified. (GT)

  6. Peer reviews and the role of a journal editor

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Obtaining peer reviews for manuscripts submitted to scientific journals is becoming increasingly difficult. Changes to the system are necessary, and editors must cultivate and maintain a solid base of reviewers to help evaluate journal submissions. This article outlines some steps editors can and sh...

  7. Journal Editor Perceptions of Universities: Some Empirical Evidence

    ERIC Educational Resources Information Center

    Mainardes, Emerson Wagner; Raposo, Mario; Alves, Helena

    2012-01-01

    Out of considerations as to the importance of university relationships with their various stakeholders, the primary objective of this research project was to identify the perceptions of academic journal editors regarding universities. Editors were asked to provide their perceptions on: (a) the relevance of universities to academic publications;…

  8. Newspaper Ethics and Managing Editors: The Evolution of APME's Code.

    ERIC Educational Resources Information Center

    De Mott, John

    A review of the 42-year development of the professional code of ethics of the Associated Press Managing Editors (APME) demonstrates an effort to elevate newspaper ethical standards around the country. Following the example of the American Society of Newspaper Editors in establishing its "Canons of Journalism" in 1923, the APME formed a criteria…

  9. How Managing Editors View and Deal with Newspaper Ethical Issues.

    ERIC Educational Resources Information Center

    Anderson, Douglas

    1987-01-01

    Claims there is awareness and concern about journalism ethics among daily newspaper managing editors. Asserts that although ethical issues are being addressed to some degree, greater efforts could be made to see that reporters and editors are apprised of codes of ethics. (MM)

  10. Editors and author resource centers actively used by attendees

    NASA Astrophysics Data System (ADS)

    Major, Barbara

    2012-02-01

    At the 2011 Fall Meeting, as in previous years, the Editors Resource Center located on the second floor of Moscone West was buzzing with activity: editors talking with other editors, collaborating with associate editors, speaking with authors, and meeting with students. In addition, several editors took part in "Meet the Editor" informal sessions, a new feature introduced for the 2011 meeting to strengthen the partnership between authors and editors. The map "Where are you from?" (see photo), outside the Editors Resource Center, drew the attention of many attendees who were eager to place their colored dots on the map. The Author Resource Center, located in the AGU Marketplace, became a hub for AGU veteran authors and potential authors alike. Staff were there to answer both editorial and technical questions, especially the most frequent one: What happens after my paper is accepted? The running slideshow that described all aspects of the AGU publications program sparked a myriad of questions, which AGU staff were happy to answer.

  11. COBrA: a bio-ontology editor.

    PubMed

    Aitken, Stuart; Korf, Roman; Webber, Bonnie; Bard, Jonathan

    2005-03-01

    COBrA is a Java-based ontology editor for bio-ontologies that distinguishes itself from other editors by supporting the linking of concepts between two ontologies, and providing sophisticated analysis and verification functions. In addition to the Gene Ontology and Open Biology Ontologies formats, COBrA can import and export ontologies in the Semantic Web formats RDF, RDFS and OWL.

  12. Martin Stutzmann: Editor, Teacher, Scientist and Friend

    NASA Astrophysics Data System (ADS)

    Cardona, Manuel

    2005-03-01

    On 2 January 1995 Martin Stutzmann became Editor-in-Chief of physica status solidi, replacing Professor E. Gutsche, who had led the journal through the stormy period involving the fall of the Iron Curtain, the unification of Germany and the change in its Eastern part, where physica status solidi was based, from socialism as found in the real world (a German concept) to real world capitalism. In 1995 it was thought that the process had been completed (we should have known better!) and after the retirement of Prof. Gutsche the new owners of physica status solidi (Wiley-VCH) decided that a change in scientific management was desirable to adapt to the new socio-political facts and to insure the scientific continuity of the journal.Martin had moved in 1993 from my department at the Max-Planck-Institute to Munich where he soon displayed a tremendous amount of science man- agement ability during the build-up of the Walter Schottky Institute. The search for a successor as Edi- tor-in-Chief was not easy: the job was not very glamorous after the upheavals which had taken place in the editorial world following the political changes. Somebody in the Editorial Boards must have suggested Martin Stutzmann. I am sure that there was opposition: one usually looks for a well-established person ready to leave his direct involvement in science and take up a new endeavor of a more administrative nature. Nevertheless, the powers that be soon realized that Martin was an excellent, if somewhat unconventional candidate who had enough energy to remain a topnotch scientist and to lead the journal in the difficult times ahead: he was offered the job. In the negotiations that followed, he insisted in getting the administrative structures that would allow him to improve the battered quality of the journal and to continue his scientific productivity. Today we are happy to see that he succeeded in both endeavors. The journal has since grown in size and considerably improved its quality

  13. EDITORIAL: Incoming Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Lidström, Suzanne

    2012-04-01

    When Professor Anders Bárány took over as the Executive Editor of Physica Scripta, in 1986, he talked of his trepidation at having to 'dress himself' in his predecessor's 'editorial coveralls'. At that time, they had been worn by Professor Nils Robert Nilsson, a major figure in the physics community, for almost 20 years. Just one year prior to this, Professor Roger Wäppling had been recruited to the position of Subeditor in conjunction with a decision to expand the number of contributions in the field of condensed matter physics, to turn it into one of the dominant subjects in the broad-based journal. Physica Scripta had already gained a reputation for being a high quality journal with wide coverage of both experimental and theoretical physics. Interestingly, in the mid 1980s, the number of papers submitted had been growing and an impressive 250 submissions per year had been attained, with all of the manuscripts being handled in-house. Not many miles away in the town of Uppsala, a group of English students was stepping off a train on a magnificent snowy day in January to embark on their final year projects. A couple of us enjoyed ourselves so much that we stayed on afterwards as PhD students, thereby encountering the mixed pleasure of studying physics in a second language for the first time. I used to copy the notes down meticulously in Swedish, then try to work backwards with a textbook to improve my language skills. One day, returning from a particularly incomprehensible lecture on solid state physics, I showed my roommates my notes and asked if they could please explain what the lecture had been about: 'I don't know', they replied, 'but this bit is about sheep!' Meanwhile, back at Physica Scripta, the journal continued to flourish: 400 submissions were received in 1996, and the march of progress was well underway. Manuscripts could now be sent in on disks and Physica Scripta was available on the World Wide Web. Roger was appointed to manage the journal and

  14. Michael hydratase alcohol dehydrogenase or just alcohol dehydrogenase?

    PubMed Central

    2014-01-01

    The Michael hydratase – alcohol dehydrogenase (MhyADH) from Alicycliphilus denitrificans was previously identified as a bi-functional enzyme performing a hydration of α,β-unsaturated ketones and subsequent oxidation of the formed alcohols. The investigations of the bi-functionality were based on a spectrophotometric assay and an activity staining in a native gel of the dehydrogenase. New insights in the recently discovered organocatalytic Michael addition of water led to the conclusion that the previously performed experiments to identify MhyADH as a bi-functional enzyme and their results need to be reconsidered and the reliability of the methodology used needs to be critically evaluated. PMID:24949265

  15. Lipase-catalyzed aza-Michael reaction on acrylate derivatives.

    PubMed

    Steunenberg, Peter; Sijm, Maarten; Zuilhof, Han; Sanders, Johan P M; Scott, Elinor L; Franssen, Maurice C R

    2013-04-19

    A methodology has been developed for an efficient and selective lipase-catalyzed aza-Michael reaction of various amines (primary and secondary) with a series of acrylates and alkylacrylates. Reaction parameters were tuned, and under the optimal conditions it was found that Pseudomonas stutzeri lipase and Chromobacterium viscosum lipase showed the highest selectivity for the aza-Michael addition to substituted alkyl acrylates. For the first time also, some CLEAs were examined that showed a comparable or higher selectivity and yield than the free enzymes and other formulations.

  16. Obituary: Michael John Seaton, 1923-2007

    NASA Astrophysics Data System (ADS)

    Pradhan, Anil; Nahar, Sultana

    2007-12-01

    Professor Michael John Seaton, hailed as the "Father of Atomic Astrophysics," passed away on May 29, 2007. He was one of the few Honorary Fellows of both the American Astronomical Society and the American Physical Society, so honored for his monumental contributions to both physics and astronomy. Mike Seaton was born on January 16, 1923 in Bristol, England. He attended Wallington County High School. But his leftist political activities, even at that stage, led to his expulsion, though he was eventually allowed to matriculate. He enlisted in the Royal Air Force as a navigator during the Second World War, and flew many dangerous missions. His legendary concentration and precision are reflected in the following anecdote. Once after a bombing mission his aircraft was lost in fog over the Alps. Seaton calculated the position and coordinates in flight to guide the aircraft. When the fog lifted, the crew found themselves flying perilously close to the mountains, but made it safely back. His associates often said, "A Seaton calculation is carried out as if his life depended on it." After the War he was admitted to University College London (UCL) as an undergraduate. Thereafter, he spent all of his professional career at UCL. Seaton received his Batchelor's degree in 1948, and his Ph.D. in 1951. His tenure at UCL coincided with the golden age of atomic astrophysics, for he was largely responsible for it. Seaton was elected Fellow of the Royal Society in 1967, and as President of the Royal Astronomical Society (RAS) in 1978. He was the recipient of an Honorary Doctorate from the Observatoire de Paris, an Honorary D.Sc. from the Queen's University of Belfast, the Gold Medal for Astronomy by the RAS, the Guthrie Medal by the Institute of Physics, the Royal Society Hughes award for lifetime work by the RAS, and several other prestigious awards. Nevertheless, as Alex Dalgarno recently remarked, Seaton was not part of the establishment because he chose not to be. Though rooted in

  17. Team of three JGR-Space Physics editors appointed

    NASA Astrophysics Data System (ADS)

    Three editors from the United States, Europe, and Asia have been appointed to lead JGR-Space Physics into the new millennium. This new team will recognize and foster the substantial contributions that scientists from the international community make to the journal. Janet Luhmann, a Senior Fellow at the Space Sciences Laboratory, University of California, Berkeley, will serve as Senior Editor. Luhmann will play a coordinating role for the regional editors, which will be especially important as the Union moves into electronic publishing and adopts new ways of using the technology to publish research findings.

  18. Retirement of J. Gary Eden as Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Jagadish, Chennupati; Jelinkova, Helena; Fainman, Yeshaiahu; Dawson, Martin; Ermers, Ysabel

    2016-01-01

    After nine years of dedicated service as Editor-in-Chief of Progress in Quantum Electronics (PQE), J. Gary Eden has retired at the end of December 2015. During his term as the Editor-in-Chief, PQE has grown significantly in size and quality and he has given generously of his time in advising authors, referees, editors, and the journal staff. Gary is an exceptional scientist and a generous individual who has given so much to the community. He is always very positive in every situation, and has created positive environment and supported people with utmost enthusiasm.

  19. ESDAPT - APT PROGRAMMING EDITOR AND INTERPRETER

    NASA Technical Reports Server (NTRS)

    Premack, T.

    1994-01-01

    ESDAPT is a graphical programming environment for developing APT (Automatically Programmed Tool) programs for controlling numerically controlled machine tools. ESDAPT has a graphical user interface that provides the user with an APT syntax sensitive text editor and windows for displaying geometry and tool paths. APT geometry statement can also be created using menus and screen picks. ESDAPT interprets APT geometry statements and displays the results in its view windows. Tool paths are generated by batching the APT source to an APT processor (COSMIC P-APT recommended). The tool paths are then displayed in the view windows. Hardcopy output of the view windows is in color PostScript format. ESDAPT is written in C-language, yacc, lex, and XView for use on Sun4 series computers running SunOS. ESDAPT requires 4Mb of disk space, 7Mb of RAM, and MIT's X Window System, Version 11 Release 4, or OpenWindows version 3 for execution. Program documentation in PostScript format and an executable for OpenWindows version 3 are provided on the distribution media. The standard distribution medium for ESDAPT is a .25 inch streaming magnetic tape cartridge (Sun QIC-24) in UNIX tar format. This program was developed in 1992.

  20. EDITORIAL: Incoming Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Webb, Steve

    2006-01-01

    Physics in Medicine and Biology (PMB) is a journal that originated in the UK but is now rightly regarded as one of the pre-eminent international journals for the publication of material coming within its remit. It is 50 years old and its maturity is an outcome of the consistent support of high performing authors, a supportive and professional publishing house, dedicated referees, many vigorous and conscientious editorial boards and the collective input of the 10 previous Editors as listed in his incoming editorial (January 2000 issue) by the retiring Editor, Professor Alun Beddoe. The scientific climate and it associated publication modus operandi in the 1950s was very different from that at the current time and the journal has evolved to reflect this. Hence today the scope of content is somewhat broader, the size of the journal is vastly greater, the whole publication process is slicker and more efficient and a paper in PMB is highly prized by its authors and those who look to quality factors and impact. The quality of the journal still relies on the voluntary labour and expertise of its busy international referees and Board members. For many years I have tried to place my own research material in PMB and encourage my teams to do likewise, not only acknowledging the prestige of the journal but also because of the extraordinarily fast turnaround time of all the processes without any loss of quality. This serves us very well and the publishing team are to be congratulated. Some things seem to change more slowly or not at all, however. The prediction, when I started my research career, that books and journals would be dinosaurs by now has manifestly not come true and, whilst most of us are addicted (and why not?) to the electronic ways of doing things that can be done by more traditional ways, PMB and a packet of reprints from time to time arriving by post still has a reassuring feel despite the fact that the papers have been `on-line' for a while before. An incoming

  1. EDITORIAL: Incoming Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Webb, Steve

    2006-01-01

    Physics in Medicine and Biology (PMB) is a journal that originated in the UK but is now rightly regarded as one of the pre-eminent international journals for the publication of material coming within its remit. It is 50 years old and its maturity is an outcome of the consistent support of high performing authors, a supportive and professional publishing house, dedicated referees, many vigorous and conscientious editorial boards and the collective input of the 10 previous Editors as listed in his incoming editorial (January 2000 issue) by the retiring Editor, Professor Alun Beddoe. The scientific climate and it associated publication modus operandi in the 1950s was very different from that at the current time and the journal has evolved to reflect this. Hence today the scope of content is somewhat broader, the size of the journal is vastly greater, the whole publication process is slicker and more efficient and a paper in PMB is highly prized by its authors and those who look to quality factors and impact. The quality of the journal still relies on the voluntary labour and expertise of its busy international referees and Board members. For many years I have tried to place my own research material in PMB and encourage my teams to do likewise, not only acknowledging the prestige of the journal but also because of the extraordinarily fast turnaround time of all the processes without any loss of quality. This serves us very well and the publishing team are to be congratulated. Some things seem to change more slowly or not at all, however. The prediction, when I started my research career, that books and journals would be dinosaurs by now has manifestly not come true and, whilst most of us are addicted (and why not?) to the electronic ways of doing things that can be done by more traditional ways, PMB and a packet of reprints from time to time arriving by post still has a reassuring feel despite the fact that the papers have been `on-line' for a while before. An incoming

  2. Martin Stutzmann: Editor, Teacher, Scientist and Friend

    NASA Astrophysics Data System (ADS)

    Cardona, Manuel

    2005-02-01

    On 2 January 1995 Martin Stutzmann became Editor-in-Chief of physica status solidi, replacing Professor E. Gutsche, who had led the journal through the stormy period involving the fall of the Iron Curtain, the unification of Germany and the change in its Eastern part, where physica status solidi was based, from socialism as found in the real world (a German concept) to real world capitalism. In 1995 it was thought that the process had been completed (we should have known better!) and after the retirement of Prof. Gutsche the new owners of physica status solidi (Wiley-VCH) decided that a change in scientific management was desirable to adapt to the new socio-political facts and to insure the scientific continuity of the journal.Martin had moved in 1993 from my department at the Max-Planck-Institute to Munich where he soon displayed a tremendous amount of science man- agement ability during the build-up of the Walter Schottky Institute. The search for a successor as Edi- tor-in-Chief was not easy: the job was not very glamorous after the upheavals which had taken place in the editorial world following the political changes. Somebody in the Editorial Boards must have suggested Martin Stutzmann. I am sure that there was opposition: one usually looks for a well-established person ready to leave his direct involvement in science and take up a new endeavor of a more administrative nature. Nevertheless, the powers that be soon realized that Martin was an excellent, if somewhat unconventional candidate who had enough energy to remain a topnotch scientist and to lead the journal in the difficult times ahead: he was offered the job. In the negotiations that followed, he insisted in getting the administrative structures that would allow him to improve the battered quality of the journal and to continue his scientific productivity. Today we are happy to see that he succeeded in both endeavors. The journal has since grown in size and considerably improved its quality

  3. Editorial independence and the editor-owner relationship: good editors never die, they just cross the line.

    PubMed

    Lapeña, J F

    2009-12-01

    The concept of editorial freedom or independence is examined in the light of the editor-owner relationship. Like individual and national freedom or independence, it is a rhetorical concept whose realisation flows from internal achievement as much as it depends on external validation. This freedom entails roles and responsibilities embodied in specific codes of practice for editors, such as the guidelines espoused by the International Committee of Medical Journal Editors and the World Association of Medical Editors. The calling to embody these guidelines makes editing a vocation that demands isolation and distancing, separation and solitude. It involves bracketing one's biases, prejudgments and preconceptions. With such detachment comes real freedom; one that requires a moral fibre and trustworthiness that uphold truth and right, whether in full view of public scrutiny, or in the aloneness of private secrecy. The stereotypical tension between academic and commercial concerns highlights the editor-owner relationship, and bears directly on editorial independence. In practice, journal owners overstep their prerogatives. The absence of clear contracts defining editorial independence and the lack of established mechanisms governing the editor-owner relationship affect many small- to medium-sized journals in developing countries. Even large journals in developed and democratic nations or totalitarian states and societies are not spared. At the end of the day, editorial freedom exists only insofar as it is tolerated, or until editors cross the line. PMID:20087545

  4. Michael Polanyi on the Education and Knowledge of Scientists.

    ERIC Educational Resources Information Center

    Jacobs, Struan

    2000-01-01

    Explains why teachers addressing the nature of science should know the work of Michael Polanyi. Outlines Polanyi's intellectual career and examines his ideas on the education of scientists, research, and knowledge. Polanyi presaged Kuhn, Feyerabend, and the constructivists, yet insisted that science produces true knowledge about reality. (Contains…

  5. Aza-Michael Reaction for an Undergraduate Organic Chemistry Laboratory

    ERIC Educational Resources Information Center

    Nigam, Manisha; Rush, Brittney; Patel, Jay; Castillo, Raul; Dhar, Preeti

    2016-01-01

    A green, aza-Michael reaction is described that can be used to teach undergraduate students conjugate addition of nitrogen nucleophile to an a,ß-unsaturated ester. Students analyze spectral data of the product obtained from the assigned reaction to determine product structure and propose the mechanism of its formation. The experiment requires…

  6. The Holocaust and Education: An Interview with Michael Berenbaum.

    ERIC Educational Resources Information Center

    Goldberg, Mark

    1997-01-01

    In January 1997, Michael Berenbaum became president and chief executive officer of Survivors of the Shoah Visual History Foundation, the organization established by filmmaker Steven Spielberg after completing "Schindler's List." Since 1994, the foundation has been recording eyewitness testimony on the Holocaust. Berenbaum's mandate is to share…

  7. Writing before the Letter: Reading Michael Ondaatje's "Handwriting"

    ERIC Educational Resources Information Center

    Festino, Cielo G.

    2006-01-01

    The purpose of this paper is to offer a reading of "Handwriting", the book of poems by the Canadian-Sri Lankan author, Michael Ondaatje, in which he recovers the recent and ancient cultural history of the island through his reading of different types of scripts and languages. The texts that Ondaatje rewrites in his poems are visual, written, oral…

  8. Reading Michael Apple--The Sociological Imagination at Work

    ERIC Educational Resources Information Center

    Ball, Stephen J.

    2007-01-01

    This article discusses Michael Apple's contribution to the sociology of education and education policy analysis and the politics of education. It focuses on ways of "reading" Apple as an intellectual and an activist and looks at the trajectory of his work over a long and illustrious career.

  9. HEADSTONES OF BERNARD AND MICHAEL JODD, FATHERANDSON CIVILIANS RESPONSIBLE FOR ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    HEADSTONES OF BERNARD AND MICHAEL JODD, FATHER-AND-SON CIVILIANS RESPONSIBLE FOR CONSTRUCTION OF BRICK PERIMETER WALL WHO DIED OF YELLOW FEVER DURING WALL CONSTRUCTION. VIEW TO WEST. - Baton Rouge National Cemetery, 220 North 19th Street, Baton Rouge, East Baton Rouge Parish, LA

  10. Michael Stipe Wake-Up Song and Greeting

    NASA Video Gallery

    The four astronauts of the final space shuttle mission are greeted by R.E.M. front man Michael Stipe and the group’s hit, "Man on the Moon" to begin Flight Day 7. On recording this song for the A...

  11. Major Michael J. Colburn: A Passion for Music Shapes Lives

    ERIC Educational Resources Information Center

    Colburn, Michael J.

    2004-01-01

    This article is adapted from a speech given by Major Michael J. Colburn executive officer and senior assistant director of the United States Marine Band, to the MENC Summer Leadership Conference July 12-15, 2003 at the MENC national headquarters in Reston, Virginia. In this article, Colburn shares three personal anecdotes that he considers to be…

  12. What Works, Works Everywhere: Q&A with Michael Barber

    ERIC Educational Resources Information Center

    Crow, Tracy

    2009-01-01

    This article presents an interview with Michael Barber, a partner at McKinsey & Company, leading its global education practice. He has been working on major challenges of performance, organization, and reform in government and the public services, especially education, in the U.S., U.K., and other countries. Barber was instrumental in preparing…

  13. Perfil de Michael López- Alegría

    NASA Video Gallery

    Conoce al astronauta de la NASA Michael López-Alegría, veterano de cuatro vuelos espaciales. Lleva registrados 257 días en el espacio y llevó a cabo 10 paseos espaciales. Conoce lo que lo inspiró a...

  14. "No More Excuses": Michael M. Crow on Analytics

    ERIC Educational Resources Information Center

    Crow, Michael M.

    2012-01-01

    Michael M. Crow became the 16th president of Arizona State University in July 2002, with the goal of transforming ASU into what he calls a "New American University"--an institution combining the highest levels of academic excellence, inclusiveness to a broad demographic, and maximum societal impact. His view included increasing graduate numbers,…

  15. The Epistemic Criterion: A Response to Michael Hand

    ERIC Educational Resources Information Center

    Cooling, Trevor

    2014-01-01

    This article is a response to Michael Hand's critique in this issue of my response to his use of the epistemic criterion as the sole means for identifying whether or not an issue should be identified as controversial. I argue that he has misunderstood my intention in suggesting that I was seeking to replace the epistemic criterion. Rather my…

  16. Michael Young, Knowledge and Curriculum: An International Dialogue

    ERIC Educational Resources Information Center

    Deng, Zongyi

    2015-01-01

    This issue of the "Journal of Curriculum Studies" presents a symposium on the recent work of Michael Young. Contemporary curriculum theory has little specific to say about how knowledge is selected, organized and transformed into curriculum content for teaching and learning. Over the last two decades, Young has taken a rather different…

  17. A Good Time: A Conversation with C. Michael Nelson

    ERIC Educational Resources Information Center

    Zabel, Robert; Kaff, Marilyn; Teagarden, Jim

    2015-01-01

    C. Michael Nelson began his special education career as a teacher of adolescents with learning and behavior disorders. He has worked as a child psychologist and as a professor with the Department of Special Education and Rehabilitation Counseling at the University of Kentucky. He coordinated the graduate Personnel Preparation Program for Teachers…

  18. Michael Young and the Politics of the School Curriculum

    ERIC Educational Resources Information Center

    Morgan, John

    2015-01-01

    Michael Young's work is central to debates about knowledge and the school curriculum. In recent years he has renounced his early argument that school subjects represent the "knowledge of the powerful", arguing instead that access and equality for all students are dependent on ensuring that all get access to "powerful…

  19. STS-73 MS Michael E. Lopez-Alegria suits up

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-73 Mission Specialist Michael E. Lopez-Alegria is donning his launch/entry suit in the Operations and Checkout Building. The seven-member crew of Mission STS-73 will depart shortly for Launch Pad 39B, where the Space Shuttle Columbia awaits another liftoff attempt at 9:50 a.m. EDT.

  20. Insight into the Mechanism of the Michael Reaction.

    PubMed

    Giraldo, Carolina; Gómez, Sara; Weinhold, Frank; Restrepo, Albeiro

    2016-07-01

    The mechanism for the nucleophilic addition step of the Michael reaction between methanethiol as a model Michael donor and several α-substituted methyl acrylates (X=F, Cl, Me, H, CN, NO2 ) as model Michael acceptors is described in detail. We suggest a novel way to condense electrophilic Fukui functions at specific atoms in terms of the contributions from the atomic orbitals to the LUMO or, more generally, to the orbital controlling the reaction. This procedure correctly associates activation energies to local electrophilic Fukui indices for the cases treated in this work. The calculated reaction barriers strongly depend on the nature of the substituent. As a general rule, activation energies are governed by structural changes, although electronic factors are significant for electron-withdrawing groups. Nucleophilic addition to Michael receptors is best described as a highly nonsynchronous process, in which the geometry of the transition state comprises a nonplanar six-membered ring. Formation of the S⋅⋅⋅C bond, which defines the interaction between the reactants, progresses ahead of all other primitive processes in the early stages of the transformation. In view of our results, we postulate that highly complex chemical reactions, as is the case for the nucleophilic addition step studied herein, that involve cleavage/formation of a total of six bonds, lower their activation energies by favoring nonsynchronicity, that is, for these types of systems, primitive changes should advance at different rates.

  1. Astronaut Michael Clifford takes a break during bailout training

    NASA Technical Reports Server (NTRS)

    1993-01-01

    Astronaut Michael R.U. (Rich) Clifford takes a break while video taping crew mates in training in the JSC Weightless Environment Training Facility (WETF). He is pictured with Trent G. Keeple, a member of the training staff assigned to STS-59.

  2. Educational Implications of Michael Fishbane's "Sacred Attunement: A Jewish Theology"

    ERIC Educational Resources Information Center

    Marom, Daniel

    2008-01-01

    This article posits Michael Fishbane's Judaic scholarship as a prime resource for Jewish education. The link between the two fields can be made through a translation of the theological underpinnings of Fishbane's insights into Judaism to educational purposes and practices. Initial work with Jewish educators on establishing this link encouraged…

  3. Genres and Genre Theory: A Response to Michael Rosen

    ERIC Educational Resources Information Center

    Christie, Frances

    2013-01-01

    This paper responds to Michael Rosen's blog entries, "How Genre Theory Saved the World", arguing that genre theory in the tradition of systemic functional linguistics (SFL) has made an important contribution to language and literacy pedagogy. It emerged in the Australian context in about 1980 and was initially developed in response to…

  4. Tweeting Prayers and Communicating Grief over Michael Jackson Online

    ERIC Educational Resources Information Center

    Sanderson, Jimmy; Cheong, Pauline Hope

    2010-01-01

    Death and bereavement are human experiences that new media helps facilitate alongside creating new social grief practices that occur online. This study investigated how people's postings and tweets facilitated the communication of grief after pop music icon Michael Jackson died. Drawing on past grief research, religion, and new media studies, a…

  5. Michael Scott: An Individual and the International System

    ERIC Educational Resources Information Center

    Reardon, Betty

    1971-01-01

    This article describes the efforts of Michael Scott in trying to gain dignity and justice for victims of political violence. It indicates that, though limited, there are still nonviolent recourses open to those who will not use the war system. (Author/JB)

  6. 78 FR 69661 - Michael Canales v. Edison International, EIX, Southern California Edison; Notice of Complaint

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-20

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Michael Canales v. Edison International, EIX, Southern California Edison....1, Michael Canales (Complainant) filed a formal complaint against Edison International, EIX...

  7. Dr. Michael DeBakey "is a magician of the heart…"

    MedlinePlus

    ... Home Current Issue Past Issues Then & Now Dr. Michael DeBakey "is a magician of the heart…" Past ... NLM's David Nash and admiring students from the Michael E. DeBakey High School for Health Professionals in ...

  8. Bibliography or Bust: The "Angst" of Scholarly Editors.

    ERIC Educational Resources Information Center

    Costa, Richard Hauer

    1980-01-01

    Provides evidence indicating not only that the market for articles on literature and language is saturated with submissions, but that the glut creates burgeoning problems for editors, including the problem of rejecting publishable items. (RL)

  9. Developing Taste and Judgment: Correctness and the Technical Editor.

    ERIC Educational Resources Information Center

    Amsden, Dorothy Corner; Sanders, Scott P.

    1985-01-01

    Provides a practical discussion for an editing course of the manner in which editors and writers routinely consult reference tools as they work and use what they find as the basis for editorial judgment and creativity. (HTH)

  10. Expert system for predicting reaction conditions: the Michael reaction case.

    PubMed

    Marcou, G; Aires de Sousa, J; Latino, D A R S; de Luca, A; Horvath, D; Rietsch, V; Varnek, A

    2015-02-23

    A generic chemical transformation may often be achieved under various synthetic conditions. However, for any specific reagents, only one or a few among the reported synthetic protocols may be successful. For example, Michael β-addition reactions may proceed under different choices of solvent (e.g., hydrophobic, aprotic polar, protic) and catalyst (e.g., Brønsted acid, Lewis acid, Lewis base, etc.). Chemoinformatics methods could be efficiently used to establish a relationship between the reagent structures and the required reaction conditions, which would allow synthetic chemists to waste less time and resources in trying out various protocols in search for the appropriate one. In order to address this problem, a number of 2-classes classification models have been built on a set of 198 Michael reactions retrieved from literature. Trained models discriminate between processes that are compatible and respectively processes not feasible under a specific reaction condition option (feasible or not with a Lewis acid catalyst, feasible or not in hydrophobic solvent, etc.). Eight distinct models were built to decide the compatibility of a Michael addition process with each considered reaction condition option, while a ninth model was aimed to predict whether the assumed Michael addition is feasible at all. Different machine-learning methods (Support Vector Machine, Naive Bayes, and Random Forest) in combination with different types of descriptors (ISIDA fragments issued from Condensed Graphs of Reactions, MOLMAP, Electronic Effect Descriptors, and Chemistry Development Kit computed descriptors) have been used. Models have good predictive performance in 3-fold cross-validation done three times: balanced accuracy varies from 0.7 to 1. Developed models are available for the users at http://infochim.u-strasbg.fr/webserv/VSEngine.html . Eventually, these were challenged to predict feasibility conditions for ∼50 novel Michael reactions from the eNovalys database (originally

  11. Expert system for predicting reaction conditions: the Michael reaction case.

    PubMed

    Marcou, G; Aires de Sousa, J; Latino, D A R S; de Luca, A; Horvath, D; Rietsch, V; Varnek, A

    2015-02-23

    A generic chemical transformation may often be achieved under various synthetic conditions. However, for any specific reagents, only one or a few among the reported synthetic protocols may be successful. For example, Michael β-addition reactions may proceed under different choices of solvent (e.g., hydrophobic, aprotic polar, protic) and catalyst (e.g., Brønsted acid, Lewis acid, Lewis base, etc.). Chemoinformatics methods could be efficiently used to establish a relationship between the reagent structures and the required reaction conditions, which would allow synthetic chemists to waste less time and resources in trying out various protocols in search for the appropriate one. In order to address this problem, a number of 2-classes classification models have been built on a set of 198 Michael reactions retrieved from literature. Trained models discriminate between processes that are compatible and respectively processes not feasible under a specific reaction condition option (feasible or not with a Lewis acid catalyst, feasible or not in hydrophobic solvent, etc.). Eight distinct models were built to decide the compatibility of a Michael addition process with each considered reaction condition option, while a ninth model was aimed to predict whether the assumed Michael addition is feasible at all. Different machine-learning methods (Support Vector Machine, Naive Bayes, and Random Forest) in combination with different types of descriptors (ISIDA fragments issued from Condensed Graphs of Reactions, MOLMAP, Electronic Effect Descriptors, and Chemistry Development Kit computed descriptors) have been used. Models have good predictive performance in 3-fold cross-validation done three times: balanced accuracy varies from 0.7 to 1. Developed models are available for the users at http://infochim.u-strasbg.fr/webserv/VSEngine.html . Eventually, these were challenged to predict feasibility conditions for ∼50 novel Michael reactions from the eNovalys database (originally

  12. Adapting a thesis to publication style: meeting editors' expectations.

    PubMed

    Johnson, S H

    1996-01-01

    Every year hundreds of thesis reports are completed by graduate students. Many of these end up on nursing journal editors' desks, only to be rejected. What characteristics of a thesis lead to rejection? How can authors develop quality research manuscripts? How can faculty teach graduate students the difference between a thesis and manuscript. This article answers these questions by providing advice from 15 critical care and research journal editors.

  13. ANNOUNCEMENT: Greetings from the Editor and Publisher

    NASA Astrophysics Data System (ADS)

    Wäppling, Roger; Williams, Sarah

    2006-01-01

    Physica Scripta is an international physics journal published for the Royal Swedish Academy of Sciences on behalf of the Nordic Science Academies and Physical Societies. This issue marks the beginning of the partnership between the Royal Swedish Academy of Sciences and Institute of Physics Publishing (IOP). We look forward to a fruitful relationship in which Physica Scripta can profit from the international reach of IOP. Authors and readers will benefit from advance publication of articles on the web prior to receiving each month's journal issue. The peer-review system will continue to be managed by Professor Roger Wäppling who will assess each paper before assigning it to an external editor or sending it for refereeing. IOP will receive new article submissions and generate electronic documents suitable for use in the refereeing process. The editorial office in Sweden will then be responsible for these manuscripts up to the final publication decision. Accepted articles will be sent to IOP for copy-editing, typesetting, production and distribution. We aim to provide our authors, referees and readers with an enhanced service for this well-established journal. IOP will maintain and augment Physica Scripta's record in publishing a broad range of high-quality research papers and we will continue to publish Topical Issues as supplements to the regular 12 issues. The popular Comments articles will continue to be published in conjunction with regular papers under this new partnership. We hope that our subscribers will continue to enjoy reading Physica Scripta as a valuable resource for general physics research.

  14. Domino Michael-Michael and Aldol-Aldol Reactions: Diastereoselective Synthesis of Functionalized Cyclohexanone Derivatives Containing Quaternary Carbon Center.

    PubMed

    Ghorai, Manas K; Halder, Sandipan; Das, Subhomoy

    2015-10-01

    A simple strategy for the synthesis of highly functionalized cyclohexanone derivatives containing an all-carbon quaternary center from α-(aryl/alkyl)methylidene-β-keto esters or β-diketones via a K-enolate mediated domino Michael-Michael reaction sequence with moderate to good yield and excellent diastereoselectivity (de > 99%) is described. Interestingly, Li-base mediated reaction of α-arylmethylidene-β-diketones affords functionalized 3,5-dihydroxy cyclohexane derivatives as the kinetically controlled products via a domino aldol-aldol reaction sequence with excellent diastereoselectivity. Li-enolates of the β-keto esters or β-diketones undergo facile domino Michael-Michael reaction with nitro-olefins to afford the corresponding nitrocyclohexane derivatives in good yields and excellent diastereoselectivity (de > 99%). The formation of the products and the observed stereoselectivity were explained by plausible mechanisms and supported by extensive computational study. An asymmetric version of the protocol was explored with (L)-menthol derived nonracemic substrates, and the corresponding nonracemic cyclohexanone derivatives containing an all-carbon quaternary center were obtained with excellent stereoselectivity (de, ee > 99%).

  15. 76 FR 55904 - Michael J. Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... Energy Regulatory Commission Michael J. Donahue; Notice of Termination of Exemption By Implied Surrender...: Michael J. Donahue. e. Name and Location of Project: The Fairbanks Mill Project is located on the Sleeper... Information: Mr. Michael J. Donahue, Route 3, Box 269, Lincoln, NH 03251. h. FERC Contact: Tom Papsidero,...

  16. 76 FR 58264 - Michael J. Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ... Energy Regulatory Commission Michael J. Donahue; Notice of Termination of Exemption by Implied Surrender...: Michael J. Donahue. e. Name and Location of Project: The Fairbanks Mill Project is located on the Sleeper... Information: Mr. Michael J. Donahue, Route 3, Box 269, Lincoln, NH 03251. h. FERC Contact: Tom Papsidero,...

  17. EDITORIAL: Incoming Editor-in-Chief Incoming Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Birch, David

    2012-01-01

    It is a pleasure and an honour for me to be taking over as Editor-in-Chief of Measurement Science and Technology. MST is well known across research communities worldwide as a leading journal in which to publish new techniques and instrumentation. It has gained this enviable position largely because of the excellent guidance of its Editorial Board and dedicated staff at Institute of Physics Publishing over many years. I want to highlight in particular the contribution of the outgoing Editor Peter Hauptmann, and other Editors before him, in making the journal truly international. We thank Peter immensely for all his hard work in leading the journal, having exceptionally served two terms, each of five years. I come into the post of Editor at a very interesting and challenging time for research. The global recession is leading to cuts in research funding in many countries, researchers and their outputs are coming under closer scrutiny than ever before, and more is being expected of them. Journals play a critical role in monitoring and maintaining research standards, but we should be careful not to assume that journal Impact Factor is the sole measure of research quality. Although expediency may sometimes demand it, Impact Factor, as practitioners know, is subject dependent. One of the great things about science and technology for me is its level playing field. The key point is still innovation no matter where the work is done or where it is published. MST has a long pedigree of being the natural home of the highest quality papers from leading researchers wishing to report novel instrumentation and techniques. 2013 will mark the 90th anniversary of MST and we look forward to celebrating in style its sustained success. I recall with pride the first paper I published in Journal of Physics E: Scientific Instruments (as MST was previously titled) back in 1977. The paper reported the design and application of an early fluorescence lifetime spectrometer that I had constructed

  18. Tribute to Professor Anthony J. McMichael

    PubMed Central

    Swaminathan, Ashwin; Lucas, Robyn M.; Harley, David

    2014-01-01

    Emeritus Professor A. J. “Tony” McMichael (1942–2014) was an internationally renowned and pioneering Australian academic and advocate in epidemiology, who was passionate about understanding the influences of the environment on human health. In an illustrious career spanning more than four decades, he made significant contributions to the scientific community and policy discourse—including ground-breaking research related to the health of children. McMichael was a prolific academic writer with over 300 peer-reviewed papers; 160 book chapters and two sole-authored books. However, his outstanding talent was for integrating complex and seemingly unrelated strands from the environmental and health sciences into a cohesive narrative—and highlighting its relevance to lay persons, scientists and governments alike. He was instrumental in validating this nascent field of research and inspiring many others to follow his lead. PMID:27417490

  19. STS-73 MS Michael E. Lopez-Alegria suits up

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-73 Mission Specialist Michael E. Lopez-Alegria finishes donning his launch/entry suit in the Operations and Checkout Building as a suit technician lends a helping hand. The seven crew members assigned to Mission STS-73 will depart shortly for Launch Pad 39B, where the Space Shuttle Columbia awaits them and a liftoff scheduled to occur no earlier than 10:46 a.m. EDT.

  20. STS-107 Payload Commander Michael Anderson suits up for TCDT

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-107 Payload Commander Michael Anderson completes suit check prior to Terminal Countdown Demonstration Test activities, which include a simulated launch countdown at the pad. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. Launch is planned for Jan. 16, 2003, between 10 a.m. and 2 p.m. EST aboard Space Shuttle Columbia. .

  1. Anti-Selective Organocatalytic Michael Addition between Phenylacetaldehyde and Nitrostyrene.

    PubMed

    Donadío, Lucía Gandolfi; Galetti, Mariana A; Giorgi, Gianluca; Rasparini, Marcello; Comin, Maria J

    2016-09-01

    Using the reaction between phenylacetaldehyde and nitrostyrene catalyzed by pyrrolidine as a simple model, we have studied the diastereochemical outcome of the organocatalytic Michael reactions between benzylic aldehydes and nitrostyrenes. We found that the anti adduct was obtained in high yield and diastereoselection as was demonstrated by the X-ray structure of the product. In situ NMR studies showed a different reaction pathway when compared to aliphatic aldehydes that yield the syn adduct as major isomer. PMID:27442526

  2. An Update: 1976 and 1987 Editors' Predictions of Audience Reactions to Videotex and A Comparison: 1987 Audience Reactions and 1976 and 1987 Editors' Predictions.

    ERIC Educational Resources Information Center

    Davenport, Lucinda D.

    To discover if editors' perceptions of audience opinions had changed and to determine the accuracy of editors' predictions regarding readers' reactions to using videotex, a 1987 study repeated a 1976 survey of Associated Press managing editors, and compared the responses with the original survey results. Surveys were sent to 302 Associated Press…

  3. Writing filter processes for the SAGA editor, appendix G

    NASA Technical Reports Server (NTRS)

    Kirslis, Peter A.

    1985-01-01

    The SAGA editor provides a mechanism by which separate processes can be invoked during an editing session to traverse portions of the parse tree being edited. These processes, termed filter processes, read, analyze, and possibly transform the parse tree, returning the result to the editor. By defining new commands with the editor's user defined command facility, which invoke filter processes, authors of filter can provide complex operations as simple commands. A tree plotter, pretty printer, and Pascal tree transformation program were already written using this facility. The filter processes are introduced, parse tree structure is described and the library interface made available to the programmer. Also discussed is how to compile and run filter processes. Examples are presented to illustrate aspect of each of these areas.

  4. SIRE: A Simple Interactive Rule Editor for NICBES

    NASA Technical Reports Server (NTRS)

    Bykat, Alex

    1988-01-01

    To support evolution of domain expertise, and its representation in an expert system knowledge base, a user-friendly rule base editor is mandatory. The Nickel Cadmium Battery Expert System (NICBES), a prototype of an expert system for the Hubble Space Telescope power storage management system, does not provide such an editor. In the following, a description of a Simple Interactive Rule Base Editor (SIRE) for NICBES is described. The SIRE provides a consistent internal representation of the NICBES knowledge base. It supports knowledge presentation and provides a user-friendly and code language independent medium for rule addition and modification. The SIRE is integrated with NICBES via an interface module. This module provides translation of the internal representation to Prolog-type rules (Horn clauses), latter rule assertion, and a simple mechanism for rule selection for its Prolog inference engine.

  5. Visions of Students Today: A Message from the Editors

    ERIC Educational Resources Information Center

    Wentzell, G. W.; Richlin, L.; Cox. M. D.

    2012-01-01

    In Michael Wesch's (2007) now widely seen video "A Vision of Students Today" (http://www.youtube.com/watch?v=dGCJ46vyR9o), a camera pans across a large, traditional classroom where college students hold up messages about themselves as members of the current generation of learners, who have been dubbed Millennials (Howe & Strauss, 2000). The video…

  6. EDITORIAL: New Editor-in-Chief for Nanotechnology New Editor-in-Chief for Nanotechnology

    NASA Astrophysics Data System (ADS)

    Couzin, Nina

    2009-01-01

    Nanotechnology is proud to announce the appointment of Professor Mark Reed, Yale University, as the new Editor-in-Chief from January 2009. Mark Reed holds the Harold Hodgkinson Chair of Engineering and Applied Science at Yale University. He has made significant contributions in the areas of quantum dots, electronic transport in nanoscale and mesoscopic systems, artificially structured materials and devices, and molecular electronics. Professor Reed has been associated with the journal as an Editorial Board member for a number of years and we are delighted that he has agreed to take on the scientific leadership of the journal in its 20th year. We also take the opportunity to thank Professor Mark Welland, Cambridge University, for his work as Editor-in-Chief since 2001, and for presiding over the re-launch and remarkable growth of the journal since then. Nanotechnology is unique in that it was the first peer-reviewed journal in the area of nanoscience, the first issue appearing in 1990. Since then it has established a distinguished publication record and has become a leading journal covering all aspects of nanoscale science and technology, as well as specializing in in-depth, comprehensive articles not seen in letter format journals. Published weekly and featuring subject sections, the journal is truly multidisciplinary in nature and is an excellent medium to quickly deliver your research results to readers worldwide. Nanotechnology is proud to be offering some of the fastest publication times around (less than three months on average from receipt to online publication). We offer free online access to all published papers for 30 days, ensuring that anyone with access to the internet will be able to read your paper. We were also the first journal to give our authors the opportunity to communicate their research to a wider audience through nanotechweb.org and other IOP websites. See the journal's homepage at www.iop.org/Journals/nano for more details. We are looking

  7. Martin Stutzmann: Editor, Teacher, Scientist and Friend

    NASA Astrophysics Data System (ADS)

    Cardona, Manuel

    2005-02-01

    On 2 January 1995 Martin Stutzmann became Editor-in-Chief of physica status solidi, replacing Professor E. Gutsche, who had led the journal through the stormy period involving the fall of the Iron Curtain, the unification of Germany and the change in its Eastern part, where physica status solidi was based, from socialism as found in the real world (a German concept) to real world capitalism. In 1995 it was thought that the process had been completed (we should have known better!) and after the retirement of Prof. Gutsche the new owners of physica status solidi (Wiley-VCH) decided that a change in scientific management was desirable to adapt to the new socio-political facts and to insure the scientific continuity of the journal.Martin had moved in 1993 from my department at the Max-Planck-Institute to Munich where he soon displayed a tremendous amount of science man- agement ability during the build-up of the Walter Schottky Institute. The search for a successor as Edi- tor-in-Chief was not easy: the job was not very glamorous after the upheavals which had taken place in the editorial world following the political changes. Somebody in the Editorial Boards must have suggested Martin Stutzmann. I am sure that there was opposition: one usually looks for a well-established person ready to leave his direct involvement in science and take up a new endeavor of a more administrative nature. Nevertheless, the powers that be soon realized that Martin was an excellent, if somewhat unconventional candidate who had enough energy to remain a topnotch scientist and to lead the journal in the difficult times ahead: he was offered the job. In the negotiations that followed, he insisted in getting the administrative structures that would allow him to improve the battered quality of the journal and to continue his scientific productivity. Today we are happy to see that he succeeded in both endeavors. The journal has since grown in size and considerably improved its quality

  8. Martin Stutzmann: Editor, Teacher, Scientist and Friend

    NASA Astrophysics Data System (ADS)

    Cardona, Manuel

    2005-03-01

    On 2 January 1995 Martin Stutzmann became Editor-in-Chief of physica status solidi, replacing Professor E. Gutsche, who had led the journal through the stormy period involving the fall of the Iron Curtain, the unification of Germany and the change in its Eastern part, where physica status solidi was based, from socialism as found in the real world (a German concept) to real world capitalism. In 1995 it was thought that the process had been completed (we should have known better!) and after the retirement of Prof. Gutsche the new owners of physica status solidi (Wiley-VCH) decided that a change in scientific management was desirable to adapt to the new socio-political facts and to insure the scientific continuity of the journal.Martin had moved in 1993 from my department at the Max-Planck-Institute to Munich where he soon displayed a tremendous amount of science man- agement ability during the build-up of the Walter Schottky Institute. The search for a successor as Edi- tor-in-Chief was not easy: the job was not very glamorous after the upheavals which had taken place in the editorial world following the political changes. Somebody in the Editorial Boards must have suggested Martin Stutzmann. I am sure that there was opposition: one usually looks for a well-established person ready to leave his direct involvement in science and take up a new endeavor of a more administrative nature. Nevertheless, the powers that be soon realized that Martin was an excellent, if somewhat unconventional candidate who had enough energy to remain a topnotch scientist and to lead the journal in the difficult times ahead: he was offered the job. In the negotiations that followed, he insisted in getting the administrative structures that would allow him to improve the battered quality of the journal and to continue his scientific productivity. Today we are happy to see that he succeeded in both endeavors. The journal has since grown in size and considerably improved its quality

  9. Chemopreventive Agents from Physalis minima Function as Michael Reaction Acceptors

    PubMed Central

    Men, Ruizhi; Li, Ning; Ding, Chihong; Tang, Yingzhan; Xing, Yachao; Ding, Wanjing; Ma, Zhongjun

    2016-01-01

    Background: The fruits of some varieties of genus Physalis have been used as delicious fruits and functional food in the Northeast of China. Materials and Methods: To reveal the functional material basis, we performed bioactivity-guided phytochemical research and chemopreventive effect assay of the constituents from Physalis minima. Results: It was demonstrated that the ethyl acetate extract of P. minima L. (EEPM) had potential quinone reductase (QR) inducing activity with induction ratio (IR, QR induction activity) value of 1.47 ± 0.24, and glutathione binding property as potential Michael reaction acceptors (with an α, β-unsaturated ketone moiety). Furthermore, bioactivity-guided phytochemical research led eight compounds (1–8), which were elucidated as 3-isopropyl-5-acetoxycyclohexene-2-one-1 (1), isophysalin B (2), physalin G (3), physalin D (4), physalin I (5), physordinose B (6), stigmasterol-3-O-β-D-glucopyranoside (7) and 5α-6β-dihydroxyphysalin R (8) on the basis of nuclear magnetic resonance spectroscopy analyses and HRESIMS. Then, isophysalin B (2) and physordinose B (6) showed significant QR inducing activity with IR value of 2.80 ± 0.19 and 2.38 ± 0.46, respectively. SUMMARY An ultra-performance liquid chromatographic method with glutathione as the substrate was used to detect the Michael reaction acceptors in extracts of Physalis minima (EPM)We investigated the chemical constituents of EPM guided by biological activity methodIsophysalin B (1) and physordinose B (6) showed strong quinone reductase inducing activity with induction ratio values of 2.80 ± 0.19 and 2.38 ± 0.46This study generated useful information for consumers and many encourage researchers to utilize edible fruits from Physalis as a source of phytochemicals Abbreviations used: EPM: Extracts of Physalis minima, EEPM: Ethyl acetate extract of Physalis minima L., GSH: Glutathione, MRAs: Michael reaction acceptors, QR: Quinone reductase. PMID:27279713

  10. STS-107 Payload Commander Michael Anderson suits up for TCDT

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - STS-107 Payload Commander Michael Anderson smiles as he undergoes suit check prior to Terminal Countdown Demonstration Test activities, which include a simulated launch countdown at the pad. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. Launch is planned for Jan. 16, 2003, between 10 a.m. and 2 p.m. EST aboard Space Shuttle Columbia. .

  11. STS-84 M.S. Michael Foale arriving for TCDT

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-84 Mission Specialist C. Michael Foale, who will become the fifth U.S. astronaut to live and work on the Russian Space Station Mir, arrives at KSCs Shuttle Landing Facility for the STS-84 Terminal Countdown Demonstration Test (TCDT), a dress rehearsal for launch. Foale will be dropped off on Mir when the Space Shuttle Atlantis docks with Mir next month. He will become a member of the Mir 23 crew, replacing U.S. astronaut Jerry M. Linenger, who will return to Earth on Atlantis after about four months on the orbiting station. STS-84 will be the sixth Shuttle- Mir docking. Liftoff is targeted for May 15.

  12. STS-89 M.S. Michael Anderson suits up

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Michael Anderson smiles as he completes the donning of his launch/entry suit in the Operations and Checkout (O&C) Building. A major in the U.S. Air Force, Anderson has a master of science degree in physics from Creighton University. He and six fellow crew members will soon depart the O&C and head for Launch Pad 39A, where the Space Shuttle Endeavour will lift off during a launch window that opens at 9:43 p.m. EST, Jan. 22. STS-89 is the eighth of nine planned missions to dock the Space Shuttle with Russia's Mir space station.

  13. STS-73 MS Michael E. Lopez-Alegria suits up

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-73 Mission Specialist Michael E. Lopez-Alegria dons his launch/entry suit in the Operations and Checkout Building with assistance from a suit technician. STS-73 will be the first trip into space for Lopez-Alegria, who considers both Madrid, Spain, and Mission Viejo, California, to be his hometowns. Lopez-Alegria and six fellow crew members will departly shortly for Launch Pad 39B, where the Space Shuttle Columbia is undergoing final preparations for liftoff during a two and a half launch window opening at 9:41 a.m. EDT, Oct. 7.

  14. STS-107 Payload Commander Michael Anderson checks equipment at SPACEHAB

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-107 Payload Commander Michael Anderson checks equipment during training at SPACEHAB. STS-107 is a research mission. The primary payload is the first flight of the SHI Research Double Module (SHI/RDM). The experiments range from material sciences to life sciences (many rats). Also part of the payload is the Fast Reaction Experiments Enabling Science, Technology, Applications and Research (FREESTAR) that incorporates eight high priority secondary attached shuttle experiments. STS-107 is scheduled to launch July 11, 2002

  15. STS-69 Mission Specialist Michael L. Gernhardt suits up

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-69 Mission Specialist Michael L. Gernhardt dons his launch/entry suit in the Operations and Checkout Building with assistance from a suit technician. STS-69 will be the first spaceflight for Gernhardt, who is scheduled to perform an extravehicular activity, or spacewalk, during the course of the mission. He and four fellow crew members will depart shortly for Launch Pad 39A, where the Space Shuttle Endeavour awaits liftoff during a two and a half hour window opening at 11:09 a.m. EDT.

  16. STS-81 Commander Michael Baker at SLF for TCDT

    NASA Technical Reports Server (NTRS)

    1996-01-01

    STS-81 Mission Commander Michael A. Baker arrives at KSC's Shuttle Landing Facility in his NASA T-38 jet. He and five other crew members will participate in the Terminal Countdown Demonstration Test (TCDT), a dress rehearsal for the planned Jan. 12 launch. STS-81 will be the fifth Shuttle-Mir docking. During the flight, Mission Specialist J.M. 'Jerry' Linenger will transfer to the Russian Mir Space Station for an extended stay, replacing astronaut John E. Blaha, who will return to Earth on the Space Shuttle orbiter Atlantis at the conclusion of the scheduled nine-day STS-81 mission.

  17. Most Business Editors Find Journalism Graduates Still Unprepared

    ERIC Educational Resources Information Center

    Pardue, Mary Jane

    2014-01-01

    In 2002, a study was published in "Newspaper Research Journal" that explored the preparedness of graduating journalism students to cover business news. In 2012, a follow-up survey of business editors at the nation's daily newspapers was done to see whether progress had been made in the training of journalism students for the…

  18. Developing and Presenting Auditory Demonstrations: Two Sound Editor Programs

    ERIC Educational Resources Information Center

    Firment, Michael J.

    2006-01-01

    Experiencing examples of auditory phenomena can clarify textbook and lecture explanations. The addition of visual displays to auditory demonstrations can make them more understandable. Two sound editor programs, Audacity[R] and Adobe Audition Pro 2.0[R], provide excellent capabilities for the display and authoring of auditory demonstrations.…

  19. Publishing in Educational Psychology Journals: Comments from Editors

    ERIC Educational Resources Information Center

    Nihalani, Priya K.; Mayrath, Michael C.

    2008-01-01

    The following paper emphasizes the importance of publishing and learning how to publish in educational psychology journals. We have compiled a set of recommendations based on advice from editors in the field and several other sources on how to publish. Additionally, this paper provides a step-by-step guide that graduate students and junior faculty…

  20. Particle size fraction -Response: Letter to the Editors

    EPA Science Inventory

    To the Editors: We, the undersigned, would like to comment on the article by Cho et al. (Cho et al. 2009), which was published in the November 2009 issue (volume 11, number 11, page 1682-1689) of Environmental Health Perspectives. We read the paper with great interest as the dis...

  1. The Editor and the Fund Raiser: Partners or Adversaries?

    ERIC Educational Resources Information Center

    Collins, Walt; Hincker, Lawrence; Yoe, Mary Ruth; Loyless, Darrell

    1999-01-01

    In a panel format, experienced college publications editors and development professionals discussed their responses to three scenarios describing clashes between alumni magazine staff and development officers: writing donor profiles; reporting negative campus news; and publishing campaign materials in the alumni magazine. Excerpts of the…

  2. Help Students to Be Skillful Editors. Ready to Write.

    ERIC Educational Resources Information Center

    Avery, Carol

    1993-01-01

    Elementary students can become good editors by using editing skills during the writing process. Teachers must present and repeat editing topics in minilessons, provide reminders of particular skills that were addressed, teach students to use editing resources, and expect students to develop proper usage gradually. (SM)

  3. Advice for a young editor: my journey in dental journalism.

    PubMed

    Curtis, Eric K

    2005-01-01

    Editing is sometimes a good route to writing; it may certainly be useful for an editor to understand the writer's point of view. Tips are offered regarding building writing skills, developing personal discipline, and generating story ideas. Writing and editing can be a way of finding out who one is.

  4. LETTER TO EDITOR ON ARTICLE "ARSENIC MEANS BUSINESS"

    EPA Science Inventory

    The letter to the editor was written to point out that different forms of arsenic are found in source waters and that the technologies listed in the article such as POU RO will not necessarily be effective on all waters. The letter pointed out that most technologies are more eff...

  5. Using a Computerized Text-Editor in Freshman Composition.

    ERIC Educational Resources Information Center

    Gerrard, Lisa

    To determine how useful a computerized text editor would be in helping students to revise their papers, an interactive text manipulation system (Wylbur) was made available to two classes of freshman composition students at the University of California, Los Angeles. Since the course received no advance publicity, students did not know when they…

  6. IN DEFENSE OF ECORISK ASSESSMENT (LETTER TO EDITOR)

    EPA Science Inventory

    Dear Editor: We are writing to convey a more accurate portrayal of the status of ecological ("environmental" in Europe) risk assessment that was presented in the recent article by M. Power and L.S. McCarty (Fallacies in Ecological Risk Assessment Practices," August 1997, pp 370A-...

  7. September 2016 Letter to the Editor-in-Chief.

    PubMed

    2016-09-01

    Letter to the Editor-in-Chief of JOSPT as follows: "One More Cause of Failure to Validate a CPR: Overfitting" with Author's Response J Orthop Sports Phys Ther 2016;46(9):811-812. doi:10.2519/jospt.2016.0202. PMID:27581182

  8. An Editor's View of the State of Applied Developmental Psychology.

    ERIC Educational Resources Information Center

    Cocking, Rodney R.

    Addressed are issues and problems of definition that arose in establishing a new scientific journal. Specifically, the problems considered are those confronting the "Journal of Applied Developmental Psychology" (JADP) in its first 5 years of existence. The first matter of definition discussed is the editor's role. Ways in which editorial power was…

  9. Editor and authors' psychology and the chance of teaching.

    PubMed

    Grammaticos, Philip C

    2006-01-01

    It is the duty of the editor to communicate with the authors who submit their scientific work for publication. The question arises as to the best way to perform this communication. The goal is to publish papers that would make their authors proud and the readers of the journal, satisfied. This goal is expressed with honesty, kindness, politeness, diplomacy and when the editor communicated with authors from other Countries, the advice of a person familiar with the traditions of these Countries may be welcome. The unpleasant editor's duty to inform the authors of their paper being rejected, can be expressed either by writing a brief straight forward letter or by giving a more detailed answer or finally, by explaining to the authors their errors in a detailed manner, in other words, by giving them advice and consultation. In his reply to the authors whose paper has been rejected, the editor may touch a sensitive part of their behavior. Authors may consider their paper as "their intellectual child". Some times authors make unacceptable mistakes that may or may not be revealed by the reviewers. Explaining in detail errors and thus counseling the authors, is hard work for the editor but not always appreciated by the authors. The value of counseling and teaching has been emphasized even by ancient philosophers but nowadays enthusiasm in learning is sometimes lacking. Is there a solution to the above? Perhaps if "the instructions to authors" of a journal specified clearly the "submission terms" for accepting a paper for publication, then the authors could be self-evaluated and perhaps all parties concerned would be happier.

  10. Primary-tertiary diamine-catalyzed Michael addition of ketones to isatylidenemalononitrile derivatives.

    PubMed

    Kumar, Akshay; Chimni, Swapandeep Singh

    2014-01-01

    Simple primary-tertiary diamines easily derived from natural primary amino acids were used to catalyze the Michael addition of ketones with isatylidenemalononitrile derivatives. Diamine 1a in combination with D-CSA as an additive provided Michael adducts in high yield (up to 94%) and excellent enantioselectivity (up to 99%). The catalyst 1a was successfully used to catalyze the three-component version of the reaction by a domino Knoevenagel-Michael sequence. The Michael adduct 4a was transformed into spirooxindole 6 by a reduction with sodium borohydride in a highly enantioselective manner.

  11. EDITORIAL: Outgoing Editor-in-Chief Outgoing Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Hauptmann, Peter

    2012-01-01

    I started in 2002 as Editor-in-Chief of a well established journal—MST (Measurement Science and Technology). It was a time when modern means of communication offered new opportunities for the scientific community—for all scientists and engineers whether at universities, in industry or at other institutions—to access better quality information in a shorter time. This development helped us to be more efficient in our daily scientific work and to anticipate new trends faster than before. A flood of information was created by different search engines. A few online journals or journals published in emerging countries with a similar profile to MST appeared on the market. MST had to provide new answers in response to these developments. In 2002 I postulated two requirements to the journal. Firstly, the publisher has to be up to date. My impression over the years has been that IOPP is excellently organized. That has made it easier for the board members and all our reviewers to concentrate on the scientific aspects of our input to the journal. During all my visits to Bristol or my contacts with the IOPP staff I always met very professional and enthusiastic staff members. They have not only supported and encouraged the ideas and initiatives of the Editorial Board members, but they have also worked hard on establishing one of the most effective journal operations in the field of measurement science and technology. Many authors are well aware of this. Thus I am able to declare that the first requirement for a successful journal has been met. Secondly, the scientific level has to be high and the journal should attract readers from all over the world. This task was the responsibility of the Editorial Board members and of myself. Our strategy was on the one hand to ensure continuity in MST but on the other hand to be open to new trends and developments. Examples of these new aspects of the journal are fields like micro- and nanometrology, measurement techniques for

  12. How Do Washington's Newspaper Editors Evaluate Their Sources of Agricultural News?--A Survey.

    ERIC Educational Resources Information Center

    Sampson, M. W.

    This report presents the results of a questionnaire sent to the daily and weekly newspaper editors in Washington to evaluate their sources of agricultural news. Responses were obtained from 16 of 21 daily newspaper editors queried and 63 of 140 weekly editors. The questionnaire was designed to check the accuracy of newspapers' mailing addresses,…

  13. FLAn: A Free Hypermedia Editor to Create Foreign Language Learning Units

    ERIC Educational Resources Information Center

    Kilickaya, Ferit, Ed.

    2011-01-01

    Glossing words is done via special software called multimedia editors. Foreign Language Annotator (FLAn), created by Thibeault (2011), is one of these multimedia editors. FLAn (Foreign Language Annotator), a free hypermedia editor that works on both Macs and PCs, allows instructors to turn static texts into dynamic learning units by attaching…

  14. PREFACE: Introductory remarks from the Editors Introductory remarks from the Editors

    NASA Astrophysics Data System (ADS)

    Knobloch, E.; Meseguer, A.; Marques, F.

    2012-06-01

    The local organizers of the 4th BIFD (Bifurcations and Instabilities in Fluid Dynamics) Symposium held in Barcelona on 18-21 July 2011 would like to thank the editors of Fluid Dynamics Research for offering us the opportunity of publishing a peer-reviewed special issue of the journal with a selection of the contributions presented at this conference. We thank both the authors and the referees for working with us on the rather tight schedule necessary to release the issue within one year of the date of the conference. We also thank the invited speakers, B Eckhardt, L Tuckerman, and J M Vega, for contributing keynote papers to this special issue. The series of BIFD symposia started as a small workshop in Madeira, Portugal, in 2004 with no more than 20 participants. This number increased rapidly during the second and third symposia held in 2006 (Denmark) and 2009 (United Kingdom), with 40 and 110 participants, respectively. The 4th BIFD symposium has consolidated this event as one of the leading conferences in hydrodynamic stability, with nearly 200 participants from around the world. The main goal of this conference is to bring together scientists and engineers from different disciplines directly or indirectly related to fluid dynamics, bifurcation theory and hydrodynamic stability theory. The conference covered many research areas within the aforementioned fields, ranging from thermal, shear and centrifugal flows to biofluids, films, drops, viscoelastic flows and magnetohydrodynamics. The structure of the conference, with invited plenary talks and focused sessions, helped the participants find their home in the conference and share state-of-the-art knowledge within the field of hydrodynamic instabilities. The financial support from MICINN (Spanish Ministry of Science and Innovation, Grant no FIS2009-08065-E) and UPC (Universitat Politècnica de Catalunya) is greatly appreciated. The local organizers would also like to thank ETSAB (Barcelona School of Architecture

  15. From the desk of the Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Hei, Tom K.

    2015-07-01

    Life Sciences in Space Research had a prominent presence at the International Congress of Radiation Research (ICRR) meeting held in Kyoto, Japan from May 25th-29th, with seven of the eleven editors attending the meeting. A journal booth was also put up at the pre-ICRR satellite meeting on Space Radiation and Heavy Ions in Therapy (SRHITS) held a few days earlier in Osaka. Since the inception of LSSR last year, the editors and publisher have promoted the journal at a number of major conferences including COSPAR 2014 in Moscow, the annual meeting of the Radiation Research Society and the NASA Space Radiation Investigators Meeting. These efforts have increased awareness of the journal among investigators in space life sciences and related fields. The number of monthly downloads of articles from the journal website averages 2000, a respectable number for a brand new journal.

  16. The Digital Audio Editor as a Teaching and Laboratory Tool

    NASA Astrophysics Data System (ADS)

    Latta, Gregory

    2001-10-01

    Digital audio editors such as Software Audio Workshop and Cool Edit Pro are powerful tools used in the radio and audio recording fields for editing digital audio. However, they are also powerful tools in the physics classroom and laboratory. During this presentation the author will show how a digital audio editor, combined with a library of audio .wav files produced by the author as part of sabbatical work, can be used to: 1. demonstrate quantitatively and qualitatively the relationship between the decibel, sound intensity, and loudness perception, 2. demonstrate quantitatively and qualitatively the relationship between frequency and pitch perception, 3. perform additive and subtractive sound synthesis, 4. demonstrate comb filtering, 5. demonstrate constructive and destructive interference, and 6. turn the computer into an accurate signal generator (sine wave, square wave, etc.) with a frequency resolution of 1Hz. Availability of the required software and .wav file library will also be discussed.

  17. William E. Edmonston, Jr.: Editor, 1968-1976.

    PubMed

    Kihlstrom, John F; Frischholz, Edward J

    2010-10-01

    This article is part of an occasional series profiling editors of the American Journal of Clinical Hypnosis (AJCH). William E. Edmonston was the second editor, succeeding Milton H. Erickson. His research focused on the use of conditioning paradigms and psychophysiological measures to explore a wide variety of hypnotic phenomena, leading to a "neo-Pavlovian" theory of neutral hypnosis as physiological relaxation (anesis). A longtime professor of psychology at Colgate University, he created an interdisciplinary undergraduate major in neuroscience, and was named New York State College Professor of the Year in 1988. He gave the Journal a new look, and a greater balance of clinical and experimental papers. The article also provides background on George Barton Cutten, George H. Estabrooks, and Frank A. Pattie, pioneers of hypnosis who were linked to Edmonston.

  18. 75 FR 22436 - Michael Williams-Control Exemption-St. Maries River Railroad, Inc.

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-04-28

    ... Surface Transportation Board Michael Williams-Control Exemption-St. Maries River Railroad, Inc. Michael Williams (applicant),\\1\\ a noncarrier, has filed a verified notice of exemption to acquire control of St... from STMA's parent, Potlatch Land & Lumber, LLC, by Williams Group, Inc. (WG).\\2\\ Applicant...

  19. 77 FR 61596 - Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-10-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Wheatley, Michael I.; Garrison, Drummond E.; Notice of Filing Take notice that on September 28, 2012, Michael I. Wheatley and Drummond E. Garrison submitted for filing,...

  20. A Response to Michael Newman's "Calling Transformative Learning into Question: Some Mutinous Thoughts"

    ERIC Educational Resources Information Center

    Cranton, Patricia; Kasl, Elizabeth

    2012-01-01

    This article presents the authors' response to Michael Newman's "Calling Transformative Learning into Question: Some Mutinous Thoughts". The authors begin by noting their appreciation of Michael Newman's challenge to transformative learning theory. In their response, the authors review and comment on the fatal flaws presented by Newman and then…

  1. 77 FR 41181 - CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey, v. Massachusetts...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-12

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey... (PURPA), CAlifornians for Renewable Energy, Inc., Michael E. Boyd, and Robert M. Sarvey...

  2. Markets, Marx, Modernity and Mathematics Education: A Response to Michael Apple.

    ERIC Educational Resources Information Center

    Gates, Peter

    This paper is a response to Michael Apple's paper, "What Postmodernists Forget: Cultural Capital and Official Knowledge." The paper advocates Michael's identification of the current dangers and processes of the growth of new right ideologies in the development of subjectivity, society, and education. The differences in success in the education…

  3. Reference Accuracy: Authors', Reviewers', Editors', and Publishers' Contributions

    PubMed Central

    2014-01-01

    Scientific authors are responsible for the accuracy of their writings and references to others' works. However, relying on authors is not enough when it comes to processing their manuscripts. Joint efforts of authors, peer reviewers, editors, and publishers throughout the publishing process may prevent most reference errors. This article analyzes essential aspects of bibliographic management and focuses on the importance of validating references by all stakeholders of scholarly publishing. PMID:25469055

  4. Towards a document structure editor for software requirements analysis

    NASA Technical Reports Server (NTRS)

    Kowalski, Vincent J.; Lekkos, Anthony A.

    1986-01-01

    Of the six or seven phases of the software engineering life cycle, requirements analysis tends to be the least understood and the least formalized. Correspondingly, a scarcity of useful software tools exist which aid in the development of user and system requirements. It is proposed that requirements analysis should culminate in a set of documents similar to those that usually accompany a delivered Software product. The design of a software tool, the Document Structure Editor, which facilitates the development of such documentation.

  5. STS-107 Crew Interviews: Michael Anderson, Mission Specialist

    NASA Technical Reports Server (NTRS)

    2002-01-01

    STS-107 Mission Specialist 3 and Payload Commander Michael Anderson is seen during this preflight interview, where he gives a quick overview of the mission before answering questions about his inspiration to become an astronaut and his career path. He outlines his role in the mission in general, and specifically in conducting onboard science experiments. He discusses the following instruments and sets of experiments in detail: CM2 (Combustion Module 2), FREESTAR (Fast Reaction Enabling Science Technology and Research, MEIDEX (Mediterranean Israeli Dust Experiment) and MGM (Mechanics of Granular Materials). Anderson also mentions on-board activities and responsibilities during launch and reentry, mission training, and microgravity research. In addition, he touches on the dual work-shift nature of the mission, the use of crew members as research subjects including pre and postflight monitoring activities, the emphasis on crew safety during training and the value of international cooperation.

  6. Expedition 8 Crew Interviews: C. Michael Foale - CDR

    NASA Technical Reports Server (NTRS)

    2003-01-01

    C. Michael Foale, Commander of the Expedition 8 crew to the International Space Station (ISS), answers interview questions in this video. The questions cover: 1) The goals of the Expedition; 2) How his Mir experience prepared him for long-duration spaceflight; 3) The reaction the Columbia accident where he was training in Star City, Russia; 4) Why the rewards of spaceflight are worth the risks; 5) Why he wanted to become an astronaut; 6) His career path; 7) His influences; 8) His path of study; 9) His responsibilities on a mission; 10) What a Soyuz capsule is like; 11) What the oncoming and offgoing ISS crews will do together; 12) How the ISS science mission will be advanced during his stay; 13) Training and plans for extravehicular activity (EVA); 14) Return to Flight of Shuttle; 15) What is needed to make his mission a success; 16) The most valuable contribution of the ISS.

  7. STS-83 Mission Specialist Michael L. Gernhardt suits up

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-83 Mission Specialist Michael L. Gernhardt is assisted into his launch/entry suit in the Operations and Checkout (O&C) Building. He first flew in this capacity on STS-69. He has been a professional deep sea diver and engineer and holds a doctorate in bioengineering. Gernhardt will be in charge of the Blue shift and as flight engineer will operate and maintain the orbiter while Halsell and Still are asleep as members of the Red shift. He will also back them up on the flight deck during the ascent and re- entry phases of the mission. Gernhardt and six fellow crew members will shortly depart the O&C and head for Launch Pad 39A, where the Space Shuttle Columbia will lift off during a launch window that opens at 2:00 p.m. EST, April 4.

  8. STS-94 Mission Specialist Michael Gernhardt suits up

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-94 Mission Specialist Michael L. Gernhardt is assisted into his launch/entry suit by a suit technician in the Operations and Checkout (O&C) Building. He first flew in this capacity on STS- 69. He has been a professional deep sea diver and engineer and holds a doctorate in bioengineering. Gernhardt will be in charge of the Blue shift and as flight engineer will operate and maintain the orbiter while Halsell and Still are asleep as members of the Red shift. He will also back them up on the flight deck during the ascent and re-entry phases of the mission. Gernhardt and six fellow crew members will shortly depart the O&C and head for Launch Pad 39A, where the Space Shuttle Columbia will lift off during a launch window that opens at 1:50 a.m. EDT, July opportunity to lift off before Florida summer rain showers reached the space center.

  9. Astronaut C. Michael Foale prepares to return to JSC

    NASA Technical Reports Server (NTRS)

    1997-01-01

    At the Skid Strip on Cape Canaveral Air Station, astronaut C. Michael Foale prepares to return to the Johnson Space Center in Houston, TX. The Oct. 6 landing of the Space Shuttle orbiter Atlantis following the successful STS-86 mission returned Foale to Earth after an approximate four-and-a-half-month stay aboard the Russian Space Station Mir. Foale, a member of the Mir 24 crew, was dropped off on the Russian space station during the STS-84 mission in mid-May. He joined the STS-86 crew aboard Atlantis for the return trip to Earth. STS-86 was the seventh docking of the Space Shuttle with the Mir. STS-86 Mission Specialist David A. Wolf replaced Foale on the Russian station.

  10. STS-84 M.S. Michael Foale suits up

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-84 Mission Specialist C. Michael Foale laughs during a rare moment of relaxation just a few hours before the scheduled launch. Foale is donning his launch and entry suit in the Operations and Checkout Building. This will be Foales fourth space flight. Foale and six other crew members will depart shortly for Launch Pad 39A, where the Space Shuttle Atlantis awaits liftoff on a mission to dock with the Russian Space Station Mir. Foale will transfer to Mir for an approximate four- month stay, replacing U.S. astronaut and Mir 23 crew member Jerry M. Linenger, who has been on the Russian space station since Jan. 15. Linenger will return to Earth on Atlantis.

  11. Astronaut C. Michael Foale prepares to return to JSC

    NASA Technical Reports Server (NTRS)

    1997-01-01

    At the Skid Strip on Cape Canaveral Air Station, astronaut C. Michael Foale and his children (5-year-old Jenna, left, and 3- year-old Ian, in Foale's arms) prepare to return to the Johnson Space Center in Houston, TX. The Oct. 6 landing of the Space Shuttle orbiter Atlantis following the successful STS-86 mission returned Foale to Earth after an approximate four-and-a-half- month stay aboard the Russian Space Station Mir. Foale, a member of the Mir 24 crew, was dropped off on the Russian space station during the STS-84 mission in mid-May. He joined the STS-86 crew aboard Atlantis for the return trip to Earth. STS-86 was the seventh docking of the Space Shuttle with the Mir. STS-86 Mission Specialist David A. Wolf replaced Foale on the Russian station.

  12. Unprecedented Double aza-Michael Addition within a Sapphyrin Core.

    PubMed

    Figueira, Flávio; Marques, Igor; Farinha, Andreia S F; Tomé, Augusto C; Cavaleiro, José A S; Silva, Artur M S; Sessler, Jonathan; Félix, Vítor; Tomé, João P C

    2016-09-26

    A novel sapphyrin derivative was obtained from the reaction between a free-base sapphyrin and dimethyl acetylenedicarboxylate (DMAD). The formation of the new compound involved a double aza-Michael addition of two pyrrolic NH groups to a DMAD molecule, with the formation of a disubstituted ethano bridge. The NMR spectral data reveal a product with an unsymmetrical structure; DFT calculations provided support for a structure in which the ethano bridge links two adjacent pyrrole units. The present study provides a seemingly unprecedented example of an N,N'-dinucleophile reacting with DMAD to form a heterocyclic compound in which the two N-atoms are linked to the two sp(3) carbon atoms derived from a substituted acetylene. PMID:27533480

  13. Michael Crotty and nursing phenomenology: criticism or critique?

    PubMed

    Barkway, P

    2001-09-01

    In 1996 Michael Crotty published the text Phenomenology and nursing research in which he criticised many nurse researchers' interpretation of the methodology of phenomenology and their utilisation of phenomenology as a method for undertaking qualitative nursing research. Crotty's thesis proposes that the research conducted by nurses is not phenomenology according to the European tradition, but a North American hybrid. Subsequently, debate has occurred amongst nurses as to whether Crotty's work is a scholarly, reasoned critique or a severe, judgmental, fault-finding criticism of nursing research. Considering the increasing utilisation of phenomenology as a methodology that informs nursing research, this debate is an important one and has implications for the conduct of research. This article examines this debate and the implications of Crotty's work for phenomenological research in nursing.

  14. Authors, editors, and the signs, symptoms and causes of plagiarism

    PubMed Central

    Shashok, Karen

    2011-01-01

    Plagiarism and inadequate citing appear to have reached epidemic proportions in research publication. This article discusses how plagiarism is defined and suggests some possible causes for the increase in the plagiarism disease. Most editors do not have much tolerance for text re-use with inadequate citation regardless of reasons why words are copied from other sources without correct attribution. However, there is now some awareness that re-use of words in research articles to improve the writing or “the English” (which has become a common practice) should be distinguished from intentional deceit for the purpose of stealing other authors’ ideas (which appears to remain a very rare practice). Although it has become almost as easy for editors to detect duplicate text as it is for authors to re-use text from other sources, editors often fail to consider the reasons why researchers resort to this strategy, and tend to consider any text duplication as a symptom of serious misconduct. As a result, some authors may be stigmatized unfairly by being labeled as plagiarists. The article concludes with practical advice for researchers on how to improve their writing and citing skills and thus avoid accusations of plagiarism. PMID:21957412

  15. Authors, editors, and the signs, symptoms and causes of plagiarism.

    PubMed

    Shashok, Karen

    2011-07-01

    Plagiarism and inadequate citing appear to have reached epidemic proportions in research publication. This article discusses how plagiarism is defined and suggests some possible causes for the increase in the plagiarism disease. Most editors do not have much tolerance for text re-use with inadequate citation regardless of reasons why words are copied from other sources without correct attribution. However, there is now some awareness that re-use of words in research articles to improve the writing or "the English" (which has become a common practice) should be distinguished from intentional deceit for the purpose of stealing other authors' ideas (which appears to remain a very rare practice). Although it has become almost as easy for editors to detect duplicate text as it is for authors to re-use text from other sources, editors often fail to consider the reasons why researchers resort to this strategy, and tend to consider any text duplication as a symptom of serious misconduct. As a result, some authors may be stigmatized unfairly by being labeled as plagiarists. The article concludes with practical advice for researchers on how to improve their writing and citing skills and thus avoid accusations of plagiarism. PMID:21957412

  16. Statement on Publication Ethics for Editors and Publishers.

    PubMed

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Voronov, Alexander A; Gorin, Sergey V; Koroleva, Anna M; Kitas, George D

    2016-09-01

    The digitization and related developments in journal editing and publishing necessitate increasing the awareness of all stakeholders of science communication in the emerging global problems and possible solutions. Journal editors and publishers are frequently encountered with the fast-growing problems of authorship, conflicts of interest, peer review, research misconduct, unethical citations, and inappropriate journal impact metrics. While the number of erroneous and unethical research papers and wasteful, or 'predatory', journals is increasing exponentially, responsible editors are urged to 'clean' the literature by correcting or retracting related articles. Indexers are advised to implement measures for accepting truly influential and ethical journals and delisting sources with predatory publishing practices. Updating knowledge and skills of authors, editors and publishers, developing and endorsing recommendations of global editorial associations, and (re)drafting journal instructions can be viewed as potential tools for improving ethics of academic journals. The aim of this Statement is to increase awareness of all stakeholders of science communication of the emerging ethical issues in journal editing and publishing and initiate a campaign of upgrading and enforcing related journal instructions. PMID:27510376

  17. An editor's considerations in publishing industry-sponsored studies.

    PubMed

    Droller, Michael J

    2015-03-01

    The fundamental responsibility of a journal editor is to assure that studies accepted for publication provide rigorous original scientific information and reviews that are considered important to the readership. The fundamental requirements of such reports from an editor's perspective include objectivity and transparency in each of the study design, implementation of investigation methods, acquisition of data, inclusive analysis and interpretation of results, appropriate application of statistical methods, presentation of outcomes in the context of a balanced and comprehensive review of relevant literature, and meaningful conclusions. In proceeding on these presumptions, editors then have the responsibility of obtaining rigorous, objective, and constructive reviews of these reports so that they can make an unbiased decision regarding their disposition. The fundamental objective in this is to enhance the ultimate scientific validity and value of the work if and when it is accepted for publication. Guidelines have been advanced by several organizations to identify how such editorial responsibilities can be fulfilled. These guidelines also pertain to investigators, authors, and sponsors of the studies, which the various reports and reviews describe. The present article reviews these guidelines as they relate to both industry-sponsored and investigator-initiated investigations and as relevant to the variety of reports that a scientific/medical journal such as Urologic Oncology: Seminars and Original Investigations receives for publication.

  18. CMS Configuration Editor: GUI based application for user analysis job

    NASA Astrophysics Data System (ADS)

    de Cosa, A.

    2011-12-01

    We present the user interface and the software architecture of the Configuration Editor for the CMS experiment. The analysis workflow is organized in a modular way integrated within the CMS framework that organizes in a flexible way user analysis code. The Python scripting language is adopted to define the job configuration that drives the analysis workflow. It could be a challenging task for users, especially for newcomers, to develop analysis jobs managing the configuration of many required modules. For this reason a graphical tool has been conceived in order to edit and inspect configuration files. A set of common analysis tools defined in the CMS Physics Analysis Toolkit (PAT) can be steered and configured using the Config Editor. A user-defined analysis workflow can be produced starting from a standard configuration file, applying and configuring PAT tools according to the specific user requirements. CMS users can adopt this tool, the Config Editor, to create their analysis visualizing in real time which are the effects of their actions. They can visualize the structure of their configuration, look at the modules included in the workflow, inspect the dependences existing among the modules and check the data flow. They can visualize at which values parameters are set and change them according to what is required by their analysis task. The integration of common tools in the GUI needed to adopt an object-oriented structure in the Python definition of the PAT tools and the definition of a layer of abstraction from which all PAT tools inherit.

  19. A perspective on computer documentation: System developer vs. technical editor

    SciTech Connect

    Carnes, E.T.; Truett, L.F.

    1995-12-31

    Between the computer-knowledgeable {open_quotes}techie{close_quotes} and the technical writer is a chasm created by differences in knowledge bases and skills. Although this gap is widened by misunderstandings and misconceptions of system development roles, it is bridged by mutual need and dual appreciation. Often the editor/writer is {open_quotes}behind{close_quotes} from beginning to end. The writer normally joins the team after the programmers are well into system development and do not want to {open_quotes}waste time{close_quotes} discussing fundamentals. The writer is usually excluded from technical discussions because it is assumed that he/she would not understand anyway. Later in the system development cycle, the writer has no time to polish the documentation before a new version of the software is issued which implies that the documentation must be revised. Nevertheless, the editor/writer`s product is critical for the end-user`s appreciation of the software, a fact which promotes unity to complete the comprehensive package of software and documentation. This paper explores the planks in the bridge that spans the chasm between developers and their fundamental PR agents, the technical editors/writers. This paper defines approaches (e.g., The Circling Theory) and techniques (Bold Thrust!) employed for effective communication -- between software developer and technical writer as well as between the software and the end-user.

  20. Statement on Publication Ethics for Editors and Publishers.

    PubMed

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Voronov, Alexander A; Gorin, Sergey V; Koroleva, Anna M; Kitas, George D

    2016-09-01

    The digitization and related developments in journal editing and publishing necessitate increasing the awareness of all stakeholders of science communication in the emerging global problems and possible solutions. Journal editors and publishers are frequently encountered with the fast-growing problems of authorship, conflicts of interest, peer review, research misconduct, unethical citations, and inappropriate journal impact metrics. While the number of erroneous and unethical research papers and wasteful, or 'predatory', journals is increasing exponentially, responsible editors are urged to 'clean' the literature by correcting or retracting related articles. Indexers are advised to implement measures for accepting truly influential and ethical journals and delisting sources with predatory publishing practices. Updating knowledge and skills of authors, editors and publishers, developing and endorsing recommendations of global editorial associations, and (re)drafting journal instructions can be viewed as potential tools for improving ethics of academic journals. The aim of this Statement is to increase awareness of all stakeholders of science communication of the emerging ethical issues in journal editing and publishing and initiate a campaign of upgrading and enforcing related journal instructions.

  1. Statement on Publication Ethics for Editors and Publishers

    PubMed Central

    2016-01-01

    The digitization and related developments in journal editing and publishing necessitate increasing the awareness of all stakeholders of science communication in the emerging global problems and possible solutions. Journal editors and publishers are frequently encountered with the fast-growing problems of authorship, conflicts of interest, peer review, research misconduct, unethical citations, and inappropriate journal impact metrics. While the number of erroneous and unethical research papers and wasteful, or 'predatory', journals is increasing exponentially, responsible editors are urged to 'clean' the literature by correcting or retracting related articles. Indexers are advised to implement measures for accepting truly influential and ethical journals and delisting sources with predatory publishing practices. Updating knowledge and skills of authors, editors and publishers, developing and endorsing recommendations of global editorial associations, and (re)drafting journal instructions can be viewed as potential tools for improving ethics of academic journals. The aim of this Statement is to increase awareness of all stakeholders of science communication of the emerging ethical issues in journal editing and publishing and initiate a campaign of upgrading and enforcing related journal instructions. PMID:27510376

  2. STS-84 Mission Specialist C. Michael Foale in white room

    NASA Technical Reports Server (NTRS)

    1997-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-84 Mission Specialist C. Michael Foale prepares to enter the Space Shuttle Atlantis at Launch Pad 39A with help from white room closeout crew members. The fourth Shuttle mission of 1997 will be the sixth docking of the Space Shuttle with the Russian Space Station Mir. The commander is Charles J. Precourt. The pilot is Eileen Marie Collins. The five mission specialists are C. Michael Foale, Carlos I. Noriega, Edward Tsang Lu, Jean-Francois Clervoy of the European Space Agency and Elena V. Kondakova of the Russian Space Agency. The planned nine-day mission will include the exchange of Foale for U.S. astronaut and Mir 23 crew member Jerry M. Linenger, who has been on Mir since Jan. 15. Linenger transferred to Mir during the last docking mission, STS-81; he will return to Earth on Atlantis. Foale is slated to remain on Mir for about four months until he is replaced in September by STS-86 Mission Specialist Wendy B. Lawrence. During the five days Atlantis is scheduled to be docked with the Mir, the STS-84 crew and the Mir 23 crew, including two Russian cosmonauts, Commander Vasily Tsibliev and Flight Engineer Alexander Lazutkin, will participate in joint experiments. The STS-84 mission also will involve the transfer of more than 7,300 pounds of water, logistics and science equipment to and from the Mir. Atlantis is carrying a nearly 300-pound oxygen generator to replace one of two Mir units which have experienced malfunctions. The oxygen it generates is used for breathing by the Mir crew.

  3. Greetings from the new Editor-in-Chief, Ronald Stambaugh Greetings from the new Editor-in-Chief, Ronald Stambaugh

    NASA Astrophysics Data System (ADS)

    Stambaugh, Ronald

    2012-04-01

    I am very pleased to join the outstanding leadership team for the journal Nuclear Fusion as Scientific Editor. The journal's high position in the field of fusion energy research derives in no small measure from the efforts of the IAEA team in Vienna, the production and marketing of IOP Publishing, the Board of Editors led by its chairman Mitsuru Kikuchi, the Associate Editor for Inertial Confinement Max Tabak and the outgoing Scientific Editor, Paul Thomas. During Paul's five year tenure submissions have grown by over 40%. The usage of the electronic journal has grown year by year with about 300 000 full text downloads of Nuclear Fusion articles in 2011, an impressive figure due in part to the launch of the full 50 year archive. High quality has been maintained while times for peer review and publishing have been reduced and the journal achieved some of the highest impact factors ever (as high as 4.27). The journal has contributed greatly to building the international scientific basis for fusion. I was privileged to serve from 2003 to 2010 as chairman of the Coordinating Committee for the International Tokamak Physics Activity (ITPA) which published in Nuclear Fusion the first ITER Physics Basis (1999) and its later update (2007). The scientific basis that has been developed to date for fusion has led to the construction of major facilities to demonstrate the production of power-plant relevant levels of fusion reactions. We look forward to the journal continuing to play a key role in the international effort toward fusion energy as these exciting major facilities and the various approaches to fusion continue to be developed. It is clear that Nuclear Fusion maintains its position in the field because of the perceived high quality of the submissions, the refereeing and the editorial processes, and the availability and utility of the online journal. The creation of the Nuclear Fusion Prize, led by the Board of Editors chairman Mitsuru Kikuchi, for the most outstanding

  4. 77 FR 30047 - Notice of Opportunity for Public Comment on Surplus Property Release at Michael J Smith Field...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-05-21

    ... Michael J Smith Field, Beaufort, NC AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice... approximately 7.5 acres of airport property, located at the Michael J Smith Field, be used for aeronautical... Authority to release approximately 7.5 acres of airport property at the Michael J Smith Field. The...

  5. 78 FR 3913 - Public Land Order No. 7807: Withdrawal of Public Lands for the Camp Michael Monsoor Mountain...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-17

    ... Bureau of Land Management Public Land Order No. 7807: Withdrawal of Public Lands for the Camp Michael... mining laws, for a period of 20 years for use by the Department of the Navy for the Camp Michael Monsoor... public use for the Department of the Navy. The area, known as Camp Michael Monsoor Mountain...

  6. 75 FR 62635 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-12

    ... AFFAIRS Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program... needed to determine patients' satisfaction with services provided by or through the Michael E. DeBakey.... Title: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form 10-0476. OMB...

  7. 77 FR 69550 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-19

    ... AFFAIRS Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program... provided by or through the Michael E. DeBakey Home Care Program. DATES: Written comments and... information technology. Title: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form...

  8. Switchable stereocontrolled divergent synthesis induced by aza-Michael addition of deactivated primary amines under acid catalysis.

    PubMed

    Amara, Z; Drège, E; Troufflard, C; Retailleau, P; Tran Huu-Dau, M-E; Joseph, D

    2014-11-24

    Switchable tandem intramolecular aza-Michael/Michael and double aza-Michael reactions allow the oriented synthesis of highly functionalised cyclic skeletons. Conjugate addition of deactivated anilines triggers chemo- and stereo-divergent ring-closure reaction pathways with a striking selectivity depending on reaction conditions.

  9. Michael Tuomey's 1848 geological survey of South Carolina

    USGS Publications Warehouse

    Nystrom, P.G.

    1999-01-01

    One hundred and fifty years ago, Michael Tuomey completed his 'Report on the Geology of South Carolina,' the result of four years of arduous labor. The report is the first detailed and comprehensive geological description of the entire state, and it includes a geological map that shows the distribution of Coastal Plain and Piedmont-Blue Ridge units. In the sesquicentennial of Tuomey's survey, it is fitting that we recognize his important early contribution to the geology of South Carolina and the southeast. Tuomey's report is a 293-page volume with a 48-page appendix and an index. Although he gave a complete depiction of Coastal Plain geology and delineated Cretaceous, Lower Eocene, Eocene, Miocene, Post-Pliocene, and alluvial units on his map, the emphasis herein is on his mapping of the Piedmont and Blue Ridge. The metamorphic units he delineated are clay slate, mica slate, talcose slate, hornblende slate, gneiss, and lime rock. Gneiss is the most extensive unit on the map. His map shows many elements of the geologic framework we recognize today. The distribution of his clay slate unit corresponds closely with the Carolina slate and Bel Air belts as we know them now. The gneiss between the two clay slate areas matches the Kiokee belt. Areas of mica slate approximate the northern part of the Kings Mountain belt and the Chauga belt. He also recognized that his talcose slate unit was associated with gold deposits. Granitic and basaltic intrusive rocks are also delineated on the map. It shows the Newberry, Columbia, and Liberty Hill granites we recognize today. Basaltic intrusives outlined include the Bush River of western Newberry County, Dutchmans Creek, Big Wateree Creek, and Ogden gabbros. He described the regional extent of diabase dikes as occuring from Virginia to Alabama, noted their preferred direction and diagrammed their near-vertical orientation. He also referred to the distinctive soil and topography that develops on the large gabbros. Michael Tuomey

  10. Regulation of human dihydrodiol dehydrogenase by Michael acceptor xenobiotics.

    PubMed

    Ciaccio, P J; Jaiswal, A K; Tew, K D

    1994-06-01

    A human oxidoreductase (H-37) that is overexpressed in ethacrynic acid-resistant HT29 colon cells (Ciaccio, P. J., Stuart, J.E., and Tew, K.D. (1993) Mol. Pharmacol. 43, 845-853) has been identified as a dihydrodiol dehydrogenase. Translated protein from a dihydrodiol dehydrogenase cDNA isolated from a library prepared from ethacrynic acid-resistant HT29 cell poly(A+) RNA was recognized by anti-H-37 IgG and was identical in molecular weight with H-37. The isolated cDNA was identical in both nucleotide and amino acid sequences with the recently cloned liver dihydrodiol dehydrogenase (Stolz, A., Hammond, L., Lou, H., Takikawa, H., Ronk, M., and Shively, J.E. (1993) J. Biol. Chem. 268, 10448-10457). Using this cDNA as probe, we have examined its induction by Michael acceptors. The steady state dihydrodiol dehydrogenase mRNA level in the ethacrynic acid-resistant line was increased 30-fold relative to that of wild-type cells. Twenty-four hour treatment of wild-type cells with ethacrynic acid or dimethyl maleate increased mRNA 10-fold and 5-fold, respectively. These changes are accompanied by both increased protein expression and increased NADP-dependent 1-acenaphthenol oxidative activity in cell cytosol. In gel shift assays, compared to wild type controls, increased binding of NAD(P)H quinone oxidoreductase human antioxidant response element (hARE) DNA to redox labile protein complexes present in treated and resistant cell nuclear extract was observed. Ethacrynic acid induced CAT activity 2-fold in Hepa1 cells stably transfected with NAD(P)H quinone oxidoreductase hARE-tk-CAT chimeric gene construct. Thus, dihydrodiol dehydrogenase protein is inducible by de novo synthesis from mRNA by structurally related monofunctional inducer Michael acceptors. Altered in vitro binding of nuclear protein to the hARE is indirect evidence for the involvement of an element similar to hARE in the regulation of dihydrodiol dehydrogenase by these agents. PMID:7515059

  11. EDITORIAL: Greetings from the new Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Bhattacharya, P.

    2004-04-01

    On 1 January, 2004, I assumed the position of Editor-in-Chief of Journal of Physics D: Applied Physics. I will start by saying that I will do my best to justify the confidence of the journal management and publishing staff in my abilities. I was fortunate to have been able to work, as an Editorial Board member, with my predecessor, the previous Editor-in-Chief, Professor Allister Ferguson. Allister has provided a high degree of intellectual stewardship for the journal in the last five years. He has made the job appear a worthy challenge for me. I therefore take this opportunity to thank Allister on behalf of the Editorial Board and publishing staff of the journal. Several other factors contributed to my decision to accept this position. The first is the group of people who actually go about the business of publishing. The Senior Publisher, Nicola Gulley (and her predecessor Sophy Le Masurier); the Managing Editor, Jill Membrey; the Publishing Administrators, Nina Blakesley and Sarah Towell; the Production Editor, Katie Gerrard and their office staff form an amazing group and have managed to make the operation of the journal incredibly efficient. An index of this is the speed with which incoming manuscripts are processed. The average time between the receipt of a manuscript and its web publication, if accepted, is 130 days. This is three to five times shorter than for most other journals. A factor that contributes to this success is a responsive pool of referees that the publishing staff have as a valuable resource. Ultimately, the standard bearers of any journal are the referees. Therefore, a grateful `thank you' is due from all of us at J. Phys. D to all our referees, who diligently perform this honourable task. The Associate Editors of the journal, Professors Lawler, Margaritondo and O'Grady, also provide immense scientific leadership. They help in defining new directions for the journal and in the publishing process. Last, but not least, a remarkable asset of

  12. Problems faced by editors of peer reviewed medical journals.

    PubMed

    Jawaid, Shaukat A

    2004-01-01

    Forty-six medical and dental journals are published from Pakistan of which only 29 are currently recognized by the Pakistan Medical and Dental Council. Only a few are peer reviewed. Six are indexed in Medline while EMBASE Excerpta Medica and World Health Organization Index Medicus for Eastern Mediterranean Region cover others. Editors of the peer reviewed medical journals are faced with numerous problems, which relate to the authors. Some of these are: shortage of quality of manuscripts, poor quality of reviewers, problems with indexation in international indexing services particularly Medline, duplicate submission and authorship and lastly, financial problems. Patronage from the Pharma industry is the major source of revenue which itself has serious implications. Editing a medical journal is a very stressful job and the editors have to work under too many pressures. A lot of useful data is presented at medical conferences, but a vast majority of it remains unpublished for various reasons, which adversely affects the citation rate from scientists from the developing third world countries in the world of medical literature. A few lectures on medical writing and research methodology to final year medical students will expose them to the art of medical writing. Specialty organizations can be persuaded to have a session on medical writing at their conferences, which will be extremely helpful not only to the potential new authors but also others, thereby improving the quality of their manuscripts. In addition to regular seminars, workshops for authors, reviewers and training courses for editors, subscribing to local medical journals by healthcare professionals and libraries are some of the measures that will help improve the situation to a great extent.

  13. EDITORIAL: Greetings from the new Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Garcia, Ephrahim

    2008-02-01

    I am Professor Ephrahim Garcia, an Associate Professor at Sibley School of Mechanical and Aerospace Engineering at Cornell University in Ithaca, New York. I have been at Cornell University since 2002, spent four years as a Program Manager at the Defense Advanced Research Project Agency from 1998-2002, and before that seven years at the Department of Mechanical Engineering at Vanderbilt University in Nashville, Tennessee. I have served on the Editorial Advisory Board of Smart Materials and Structures (SMS) for the last six years. It is a humbling thing to be asked to take up the post of Editor-in-Chief in a field with so many talented researchers. I would like to say a heartfelt thanks to the members of the Editorial Board and IOP Publishing for their confidence in me. Most importantly, I would like to thank Professor Vijay Varadan of the University of Arkansas and Professor Richard Claus of Virginia Polytechnic Institute and State University for their efforts in launching the journal 16 years ago. They have been stewards, promoters and, especially Vijay, key to the operation and function of SMS for all these years, and our research community is indebted to them. Professors Varadan and Claus have dedicated their careers to the area of smart materials and structures and we are very grateful for their leadership, mentoring and contribution. SMS is a thriving journal offering papers on all technical areas concerned with smart materials, systems and structures from the micro- and nanoscale to the macroscale. The journal is undergoing some major changes, including the recent transferal of papers to IOP Publishing's peer-review management system. With this new system authors can expect fast publication times of around 4 or 5 months from submission, and excellent author service. In this world of ever changing technology, the Editorial Board and I aim to reduce the time to publication for researchers in this exciting area of science and engineering. I am in the process of

  14. The Matrix Editor for symbolic Jacobians in ALPAL

    SciTech Connect

    Painter, J.F.

    1991-12-01

    ALPAL is a Macsyma-based tool that automatically generates code to solve nonlinear integro-differential equations, given a very high-level specification of the equations to be solved and the numerical methods to be used. The Matrix Editor is a graphical, interactive tool for specifying the handling of Jacobian matrices and linear solvers. It automates such routine but difficult tasks as correctly converting from the data structures used for computing the Jacobian to data structures used by a linear solver. The user specifies what to do only at a high, natural level of abstraction.

  15. Astronaut Michael Collins Undergoes Communications Systems Final Check

    NASA Technical Reports Server (NTRS)

    1969-01-01

    Dunned in his space suit, Command Module (CM) pilot Michael Collins does a final check of his communications system before the boarding of the Apollo 11 mission. Launched via a Saturn V launch vehicle, the first manned lunar mission launched from the Kennedy Space Center, Florida on July 16, 1969 and safely returned to Earth on July 24, 1969. The Saturn V vehicle was developed by the Marshall Space Flight Center (MSFC) under the direction of Dr. Wernher von Braun. The 3-man crew aboard the flight consisted of astronauts Collins; Neil A. Armstrong, Mission Commander; and Edwin E. Aldrin, Jr., Lunar Module (LM) Pilot. Armstrong was the first human to ever stand on the lunar surface, followed by Edwin (Buzz) Aldrin. Meanwhile, astronaut Collins piloted the CM in a parking orbit around the Moon. During a 2½ hour surface exploration, the crew collected 47 pounds of lunar surface material which was returned to Earth for analysis. With the success of Apollo 11, the national objective to land men on the Moon and return them safely to Earth had been accomplished.

  16. STS-103 M.S. Michael Foale during TCDT activities

    NASA Technical Reports Server (NTRS)

    1999-01-01

    STS-103 Mission Specialist C. Michael Foale (Ph.D.) is ready to take his turn at driving a small armored personnel carrier that is part of emergency egress training during Terminal Countdown Demonstration Test (TCDT) activities. The tracked vehicle could be used by the crew in the event of an emergency at the pad during which the crew must make a quick exit from the area. The TCDT also provides simulated countdown exercises and opportunities to inspect the mission payloads in the orbiter's payload bay. STS-103 is a 'call-up' mission due to the need to replace and repair portions of the Hubble Space Telescope. Although Hubble is operating normally and conducting its scientific observations, only three of its six gyroscopes are working properly. Four EVA's are planned to make the necessary repairs and replacements on the telescope. The other STS-103 crew members are Commander Curtis L. Brown Jr., Pilot Scott J. Kelly, and Mission Specialists Steven L. Smith , John M. Grunsfeld (Ph.D.), and Claude Nicollier of Switzerland and Jean-Frangois Clervoy of France, who are with the European Space Agency. The mission is targeted for launch Dec. 6 at 2:37 a.m. EST.

  17. 29 CFR 793.8 - “News editor.”

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false âNews editor.â 793.8 Section 793.8 Labor Regulations... Exemption § 793.8 “News editor.” A news editor is an employee who gathers, edits and rewrites the news. He may also select and prepare news items for broadcast and present the news on the air. An employee...

  18. 29 CFR 793.8 - “News editor.”

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false âNews editor.â 793.8 Section 793.8 Labor Regulations... Exemption § 793.8 “News editor.” A news editor is an employee who gathers, edits and rewrites the news. He may also select and prepare news items for broadcast and present the news on the air. An employee...

  19. Suppression of pro-inflammatory and proliferative pathways by diferuloylmethane (curcumin) and its analogues dibenzoylmethane, dibenzoylpropane, and dibenzylideneacetone: role of Michael acceptors and Michael donors.

    PubMed

    Anand, Preetha; Sung, Bokyung; Kunnumakkara, Ajaikumar B; Rajasekharan, Kallikat N; Aggarwal, Bharat B

    2011-12-15

    Curcumin, a diferuloylmethane, has been shown to exhibit anti-inflammatory and anti-proliferative activities. Whereas curcumin has both a Michael acceptor and a Michael donor units, its analogues dibenzoylmethane (DBM, a component of licorice) and dibenzoylpropane (DBP) have a Michael donor but not a Michael acceptor unit, and the analogue dibenzylideneacetone (DBA) has a Michael acceptor unit. In the current report, we investigated the potency of DBM, DBP, and DBA in relation to curcumin for their ability to suppress TNF-induced NF-κB activation, NF-κB-regulated gene products, and cell proliferation. We found that all four agents were active in suppressing NF-κB activation; curcumin was most active and DBM was least active. When examined for its ability to inhibit the direct DNA binding activity of p65, a subunit of NF-κB, only DBP inhibited the binding. For inhibition of TNF-induced IKK activation, DBA was most active. For suppression of TNF-induced expression of NF-κB-regulated gene products such as COX-2 (inflammation marker), cyclin D1 (proliferation marker), and VEGF (angiogenesis marker), DBA and curcumin were more active than DBM. Similarly for suppression of proliferation of leukemia (KBM-5), T cell leukemia (Jurkat), prostate (DU145), and breast (MDA-MB-231) cancer cells, curcumin and DBA were most active and DBP was least active. Overall, our results indicate that although curcumin and its analogues exhibit activities to suppress inflammatory pathways and cellular proliferation, a lack of Michael acceptor units in DBM and DBP can reduce their activities.

  20. Gene targeting, genome editing: from Dolly to editors.

    PubMed

    Tan, Wenfang; Proudfoot, Chris; Lillico, Simon G; Whitelaw, C Bruce A

    2016-06-01

    One of the most powerful strategies to investigate biology we have as scientists, is the ability to transfer genetic material in a controlled and deliberate manner between organisms. When applied to livestock, applications worthy of commercial venture can be devised. Although initial methods used to generate transgenic livestock resulted in random transgene insertion, the development of SCNT technology enabled homologous recombination gene targeting strategies to be used in livestock. Much has been accomplished using this approach. However, now we have the ability to change a specific base in the genome without leaving any other DNA mark, with no need for a transgene. With the advent of the genome editors this is now possible and like other significant technological leaps, the result is an even greater diversity of possible applications. Indeed, in merely 5 years, these 'molecular scissors' have enabled the production of more than 300 differently edited pigs, cattle, sheep and goats. The advent of genome editors has brought genetic engineering of livestock to a position where industry, the public and politicians are all eager to see real use of genetically engineered livestock to address societal needs. Since the first transgenic livestock reported just over three decades ago the field of livestock biotechnology has come a long way-but the most exciting period is just starting.

  1. Gene targeting, genome editing: from Dolly to editors.

    PubMed

    Tan, Wenfang; Proudfoot, Chris; Lillico, Simon G; Whitelaw, C Bruce A

    2016-06-01

    One of the most powerful strategies to investigate biology we have as scientists, is the ability to transfer genetic material in a controlled and deliberate manner between organisms. When applied to livestock, applications worthy of commercial venture can be devised. Although initial methods used to generate transgenic livestock resulted in random transgene insertion, the development of SCNT technology enabled homologous recombination gene targeting strategies to be used in livestock. Much has been accomplished using this approach. However, now we have the ability to change a specific base in the genome without leaving any other DNA mark, with no need for a transgene. With the advent of the genome editors this is now possible and like other significant technological leaps, the result is an even greater diversity of possible applications. Indeed, in merely 5 years, these 'molecular scissors' have enabled the production of more than 300 differently edited pigs, cattle, sheep and goats. The advent of genome editors has brought genetic engineering of livestock to a position where industry, the public and politicians are all eager to see real use of genetically engineered livestock to address societal needs. Since the first transgenic livestock reported just over three decades ago the field of livestock biotechnology has come a long way-but the most exciting period is just starting. PMID:26847670

  2. Reconstruct: a free editor for serial section microscopy.

    PubMed

    Fiala, J C

    2005-04-01

    Many microscopy studies require reconstruction from serial sections, a method of analysis that is sometimes difficult and time-consuming. When each section is cut, mounted and imaged separately, section images must be montaged and realigned to accurately analyse and visualize the three-dimensional (3D) structure. Reconstruct is a free editor designed to facilitate montaging, alignment, analysis and visualization of serial sections. The methods used by Reconstruct for organizing, transforming and displaying data enable the analysis of series with large numbers of sections and images over a large range of magnifications by making efficient use of computer memory. Alignments can correct for some types of non-linear deformations, including cracks and folds, as often encountered in serial electron microscopy. A large number of different structures can be easily traced and placed together in a single 3D scene that can be animated or saved. As a flexible editor, Reconstruct can reduce the time and resources expended for serial section studies and allows a larger tissue volume to be analysed more quickly.

  3. End notes: two unpublished presentations by Michael Fordham.

    PubMed

    Urban, Elizabeth

    2013-09-01

    Following the publication in this journal of two of Fordham's unpublished papers selected by James Astor (2010, 55, 5), the editors have asked me to select a further two. I have chosen two clinical pieces, one clinical notes and the other notes that refine his previous thinking, which Fordham wrote at the end of his life. Both are examples of the way Fordham continued throughout his analytic work to turn to patients as his primary source of learning. Fordham presented the first piece, 'A case study', to Parkside Clinic in 1988. Its subject is his last child patient, a nine-year-old boy with behaviour problems that destroyed the analytic frame. The second is clearly for an SAP (Society of Analytical Psychology) audience and written probably around 1992-93. It is titled 'Some comments on transference and countertransference' and contains material from the patient who has become known through papers in this journal as 'K'. The two pieces are presented together within a commentary rather than separately with footnotes, in order to provide some context for Fordham's thinking in his late years. PMID:24010777

  4. Letters to the editor: definitely not children of a lesser god.

    PubMed

    Papanas, N; Georgiadis, G S; Maltezos, E; Lazarides, M K

    2009-10-01

    Letters to the editor are brief texts that are published in a special section of medical journals. There are two types of letters to the editor: the observation and the comment. The former presents original work, while the latter constitutes criticism on work already published in the same journal. Although short, letters to the editor require as much effort and discipline in writing as, indeed, any other manuscript. Clarity and brevity should be their principal values. It is also important to comply with the journals' instructions for correspondence. Thus, eloquent letters to the editor may promote knowledge and enable fruitful exchange of ideas.

  5. Chiral Aminophosphines as Catalysts for Enantioselective Double-Michael Indoline Syntheses

    PubMed Central

    Khong, San N.; Kwon, Ohyun

    2014-01-01

    The bisphosphine-catalyzed double-Michael addition of dinucleophiles to electron-deficient acetylenes is an efficient process for the synthesis of many nitrogen-containing heterocycles. Because the resulting heterocycles contain at least one stereogenic center, this double-Michael reaction would be even more useful if an asymmetric variant of the reaction were to be developed. Aminophosphines can also facilitate the double-Michael reaction and chiral amines are more readily available in Nature and synthetically; therefore, in this study we prepared several new chiral aminophosphines. When employed in the asymmetric double-Michael reaction between ortho-tosylamidophenyl malonate and 3-butyn-2-one, the chiral aminophosphines produced indolines in excellent yields with moderate asymmetric induction. PMID:22580397

  6. Tandem bis-aza-Michael addition reaction of amines in aqueous medium promoted by polystyrenesulfonic Acid

    EPA Science Inventory

    An efficient and environmentally benign tandem bis-aza-Michael addition of amines catalyzed by polystyrene sulfonic acid (PSSA) is described. This operationally simple high yielding microwave assisted synthetic protocol proceeded in water in the absence of any organic solvent.

  7. High Blood Cholesterol Q&A Dr. Michael Lauer | NIH MedlinePlus the Magazine

    MedlinePlus

    ... this page please turn Javascript on. Feature: High Cholesterol High Blood Cholesterol Q&A with Dr. Michael Lauer Past Issues / ... heavier and older, what does recent research on cholesterol and heart health tell us that Americans need ...

  8. Theory and practice in action: the contributions of Michael Perkins to clinical linguistics.

    PubMed

    Damico, Jack S; Lynch, Karen E

    2013-01-01

    This article reviews the scholarly contributions of Michael R. Perkins in the discipline of clinical linguistics and provides some indication of the reasons that he has been so successful. Three primary attributes were described through an analysis of his publications.

  9. Trimethylsilylethynyl ketones as surrogates for ethynyl ketones in the double Michael reaction.

    PubMed

    Holeman, Derrick S; Rasne, Ravindra M; Grossman, Robert B

    2002-05-01

    Trimethylsilylethynyl ketones can be desilylated in the presence of a tethered carbon diacid and induced to undergo a double Michael reaction in situ. The trimethylsilylethynyl ketones can serve as surrogates of ethynyl ketones that are difficult to prepare or isolate.

  10. Design of reversible, cysteine-targeted Michael acceptors guided by kinetic and computational analysis.

    PubMed

    Krishnan, Shyam; Miller, Rand M; Tian, Boxue; Mullins, R Dyche; Jacobson, Matthew P; Taunton, Jack

    2014-09-10

    Electrophilic probes that covalently modify a cysteine thiol often show enhanced pharmacological potency and selectivity. Although reversible Michael acceptors have been reported, the structural requirements for reversibility are poorly understood. Here, we report a novel class of acrylonitrile-based Michael acceptors, activated by aryl or heteroaryl electron-withdrawing groups. We demonstrate that thiol adducts of these acrylonitriles undergo β-elimination at rates that span more than 3 orders of magnitude. These rates correlate inversely with the computed proton affinity of the corresponding carbanions, enabling the intrinsic reversibility of the thiol-Michael reaction to be tuned in a predictable manner. We apply these principles to the design of new reversible covalent kinase inhibitors with improved properties. A cocrystal structure of one such inhibitor reveals specific noncovalent interactions between the 1,2,4-triazole activating group and the kinase. Our experimental and computational study enables the design of new Michael acceptors, expanding the palette of reversible, cysteine-targeted electrophiles.

  11. Helical-Peptide-Catalyzed Enantioselective Michael Addition Reactions and Their Mechanistic Insights.

    PubMed

    Ueda, Atsushi; Umeno, Tomohiro; Doi, Mitsunobu; Akagawa, Kengo; Kudo, Kazuaki; Tanaka, Masakazu

    2016-08-01

    Helical peptide foldamer catalyzed Michael addition reactions of nitroalkane or dialkyl malonate to α,β-unsaturated ketones are reported along with the mechanistic considerations of the enantio-induction. A wide variety of α,β-unsaturated ketones, including β-aryl, β-alkyl enones, and cyclic enones, were found to be catalyzed by the helical peptide to give Michael adducts with high enantioselectivities (up to 99%). On the basis of X-ray crystallographic analysis and depsipeptide study, the amide protons, N(2)-H and N(3)-H, at the N terminus in the α-helical peptide catalyst were crucial for activating Michael donors, while the N-terminal primary amine activated Michael acceptors through the formation of iminium ion intermediates.

  12. STS-34 Pilot Michael J. McCulley during T-30 press briefing at JSC

    NASA Technical Reports Server (NTRS)

    1989-01-01

    STS-34 Atlantis, Orbiter Vehicle (OV) 104, Pilot Michael J. McCulley reflects on a question during the thirty days before launch (T-30) press briefing in the JSC Auditorium and Public Affairs Facility Bldg 2 briefing room.

  13. A Generic Metadata Editor Supporting System Using Drupal CMS

    NASA Astrophysics Data System (ADS)

    Pan, J.; Banks, N. G.; Leggott, M.

    2011-12-01

    Metadata handling is a key factor in preserving and reusing scientific data. In recent years, standardized structural metadata has become widely used in Geoscience communities. However, there exist many different standards in Geosciences, such as the current version of the Federal Geographic Data Committee's Content Standard for Digital Geospatial Metadata (FGDC CSDGM), the Ecological Markup Language (EML), the Geography Markup Language (GML), and the emerging ISO 19115 and related standards. In addition, there are many different subsets within the Geoscience subdomain such as the Biological Profile of the FGDC (CSDGM), or for geopolitical regions, such as the European Profile or the North American Profile in the ISO standards. It is therefore desirable to have a software foundation to support metadata creation and editing for multiple standards and profiles, without re-inventing the wheels. We have developed a software module as a generic, flexible software system to do just that: to facilitate the support for multiple metadata standards and profiles. The software consists of a set of modules for the Drupal Content Management System (CMS), with minimal inter-dependencies to other Drupal modules. There are two steps in using the system's metadata functions. First, an administrator can use the system to design a user form, based on an XML schema and its instances. The form definition is named and stored in the Drupal database as a XML blob content. Second, users in an editor role can then use the persisted XML definition to render an actual metadata entry form, for creating or editing a metadata record. Behind the scenes, the form definition XML is transformed into a PHP array, which is then rendered via Drupal Form API. When the form is submitted the posted values are used to modify a metadata record. Drupal hooks can be used to perform custom processing on metadata record before and after submission. It is trivial to store the metadata record as an actual XML file

  14. Roseopurpurins: Chemical Diversity Enhanced by Convergent Biosynthesis and Forward and Reverse Michael Additions.

    PubMed

    Shang, Zhuo; Khalil, Zeinab; Li, Li; Salim, Angela A; Quezada, Michelle; Kalansuriya, Pabasara; Capon, Robert J

    2016-09-01

    Cultures of the estuarine fungus Penicillium roseopurpureum (CMB-MF038) yielded a diverse array of polyketides, many of which were related via a highly convergent biosynthetic pathway. In addition to revising and assigning structures, and documenting chemical and biological properties, pro-drug cytotoxic properties were attributed to roseopurpurins H (10) and I (11) on the basis of in situ reverse Michael addition to a cytotoxic Michael acceptor (12). PMID:27537356

  15. A Fresh Wind is Blowing in from Asia Professor Michael Raghunath Arrives at ZHAW Waedenswil.

    PubMed

    Heinzelmann, Elsbeth

    2016-01-01

    In summer 2016, Michael Raghunath from the National University of Singapore (NUS) will take over the professorship from Ursula Graf-Hausner in cell culture technology and tissue engineering at ZHAW Life Sciences and Facility Management. What are his objectives and the corresponding strategies? What challenges will he face, what will he choose to focus on? Michael Raghunath was kind enough to let us have a look behind the scenes. PMID:27363381

  16. Portable EDITOR (PEDITOR): A portable image processing system. [satellite images

    NASA Technical Reports Server (NTRS)

    Angelici, G.; Slye, R.; Ozga, M.; Ritter, P.

    1986-01-01

    The PEDITOR image processing system was created to be readily transferable from one type of computer system to another. While nearly identical in function and operation to its predecessor, EDITOR, PEDITOR employs additional techniques which greatly enhance its portability. These cover system structure and processing. In order to confirm the portability of the software system, two different types of computer systems running greatly differing operating systems were used as target machines. A DEC-20 computer running the TOPS-20 operating system and using a Pascal Compiler was utilized for initial code development. The remaining programmers used a Motorola Corporation 68000-based Forward Technology FT-3000 supermicrocomputer running the UNIX-based XENIX operating system and using the Silicon Valley Software Pascal compiler and the XENIX C compiler for their initial code development.

  17. Educating science editors: is there a comprehensive strategy?

    PubMed Central

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Gorin, Sergey V.; Kitas, George D.

    2014-01-01

    The article considers available options to educate science editors in the fast-transforming digital environment. There is no single course or resource that can cover their constantly changing and diversifying educational needs. The involvement in research, writing, and reviewing is important for gaining editing skills, but that is not all. Membership in editorial associations and access to updated scholarly information in the field are mandatory for maintaining editorial credentials. Learned associations offer access to a few widely-recognized periodicals. There are also formal training courses covering issues in science writing and ethical editing, but no high-level evidence data exist to promote any of these. Networking with like-minded specialists within the global and regional editorial associations seems a useful strategy to upgrade editorial skills and resolve problems with the quality control and digitization of scholarly periodicals. PMID:25559840

  18. A Diagram Editor for Efficient Biomedical Knowledge Capture and Integration

    PubMed Central

    Yu, Bohua; Jakupovic, Elvis; Wilson, Justin; Dai, Manhong; Xuan, Weijian; Mirel, Barbara; Athey, Brian; Watson, Stanley; Meng, Fan

    2008-01-01

    Understanding the molecular mechanisms underlying complex disorders requires the integration of data and knowledge from different sources including free text literature and various biomedical databases. To facilitate this process, we created the Biomedical Concept Diagram Editor (BCDE) to help researchers distill knowledge from data and literature and aid the process of hypothesis development. A key feature of BCDE is the ability to capture information with a simple drag-and-drop. This is a vast improvement over manual methods of knowledge and data recording and greatly increases the efficiency of the biomedical researcher. BCDE also provides a unique concept matching function to enforce consistent terminology, which enables conceptual relationships deposited by different researchers in the BCDE database to be mined and integrated for intelligible and useful results. We hope BCDE will promote the sharing and integration of knowledge from different researchers for effective hypothesis development. PMID:21347131

  19. The X-windows interactive navigation data editor

    NASA Technical Reports Server (NTRS)

    Rinker, G. C.

    1992-01-01

    A new computer program called the X-Windows Interactive Data Editor (XIDE) was developed and demonstrated as a prototype application for editing radio metric data in the orbit-determination process. The program runs on a variety of workstations and employs pull-down menus and graphical displays, which allow users to easily inspect and edit radio metric data in the orbit data files received from the Deep Space Network (DSN). The XIDE program is based on the Open Software Foundation OSF/Motif Graphical User Interface (GUI) and has proven to be an efficient tool for editing radio metric data in the navigation operations environment. It was adopted by the Magellan Navigation Team as their primary data-editing tool. Because the software was designed from the beginning to be portable, the prototype was successfully moved to new workstation environments. It was also itegrated into the design of the next-generation software tool for DSN multimission navigation interactive launch support.

  20. Educating science editors: is there a comprehensive strategy?

    PubMed

    Gasparyan, Armen Yuri; Yessirkepov, Marlen; Gorin, Sergey V; Kitas, George D

    2014-12-01

    The article considers available options to educate science editors in the fast-transforming digital environment. There is no single course or resource that can cover their constantly changing and diversifying educational needs. The involvement in research, writing, and reviewing is important for gaining editing skills, but that is not all. Membership in editorial associations and access to updated scholarly information in the field are mandatory for maintaining editorial credentials. Learned associations offer access to a few widely-recognized periodicals. There are also formal training courses covering issues in science writing and ethical editing, but no high-level evidence data exist to promote any of these. Networking with like-minded specialists within the global and regional editorial associations seems a useful strategy to upgrade editorial skills and resolve problems with the quality control and digitization of scholarly periodicals.

  1. Advanced software development workstation project: Engineering scripting language. Graphical editor

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Software development is widely considered to be a bottleneck in the development of complex systems, both in terms of development and in terms of maintenance of deployed systems. Cost of software development and maintenance can also be very high. One approach to reducing costs and relieving this bottleneck is increasing the reuse of software designs and software components. A method for achieving such reuse is a software parts composition system. Such a system consists of a language for modeling software parts and their interfaces, a catalog of existing parts, an editor for combining parts, and a code generator that takes a specification and generates code for that application in the target language. The Advanced Software Development Workstation is intended to be an expert system shell designed to provide the capabilities of a software part composition system.

  2. An Internet-based ontology editor for medical appropriateness criteria.

    PubMed

    Kahn, C E

    1998-04-01

    Appropriateness criteria and practice guidelines seek to promote the cost-effectiveness use of medical interventions, and can be most useful when integrated with computer-based patient records and order-entry systems. Building an abstract model (ontology) of appropriateness criteria can require considerable effort among investigators at geographically dispersed institutions. To facilitate the construction and maintenance of ontologies for clinical appropriateness criteria, the author developed an Internet-based system for viewing and editing the knowledge model. The system, called NEON (Network-based Editor for ONtologies), uses the World Wide Web as a platform-independent user interface. NEON allows users to edit the indexing terms and the semantic network that form the ontology for a set of appropriateness criteria. Ontologies built using the system can be imported and exported using an open, internationally standardized format based on the Standard Generalized Markup Language (SGML).

  3. Letter to the editor of TAAP, in response to letter from Anders et al.

    EPA Science Inventory

    To the Editor, Toxicology and Applied Pharmacology: We would like to address the letter to the editor submitted by Anders et al. regarding the substantive issues raised regarding our paper "Evaluation of two different metabolic hypotheses for dichloromethane toxicity using physi...

  4. Letters to the Editor: Public Writing as a Response to Reading.

    ERIC Educational Resources Information Center

    Rinehammer, Nora

    A study conducted by the copy editor of a small daily newspaper in Porter County, Indiana examines readers' motivations for writing letters to the editor. Analysis was based on letters that appeared in "The Vidette Messenger" September 16-30, 1992. Of 75 letters, 32 were responses to information published in the paper during the last 2 weeks. All…

  5. Magazine Article Placement: How Editors, Regular Contributors, and Novice Writers Rate Query Letters.

    ERIC Educational Resources Information Center

    Jolliffe, Lee

    About 350,000 freelance magazine articles were purchased by magazine editors last year from the 22,000 freelancers and 225,000 would-be freelancers in the United States. A study examined the factors editors judge most important in selecting freelance magazine article proposals, using factor analysis and qualitative examination of persuasive…

  6. Debunking the Mutilated Boy: A Study of Newspaper Editors and an Inflammatory Rumor.

    ERIC Educational Resources Information Center

    Brown, Lee

    A study examined how newspaper editors resolve issues relating to rumors--that is whether to cover stories which may turn out to be false. The "mutilated boy" rumor was chosen for its antiquity and endurance, its powerful theme, and its ability to create intense anxiety in a community. Thirty-three of the 86 editors who responded to the…

  7. New Technology and the Writer/Editor Relationship: Shifting Electronic Realities.

    ERIC Educational Resources Information Center

    Endres, Kathleen L.; Schierhorn, Ann B.

    1995-01-01

    Examines the role new technology is playing in the magazine writer/editor relationship. Finds that editors report the new technology is affecting their relationship with writers, and that free-lancers are less apt to use expensive new technology than staff writers. (SR)

  8. 29 CFR 793.11 - Combination announcer, news editor and chief engineer.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 3 2011-07-01 2011-07-01 false Combination announcer, news editor and chief engineer. 793.11 Section 793.11 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT... editor and chief engineer. The 13(b)(9) exemption, as was made clear during the debate on the...

  9. "Clones," Codes, and Conflicts of Interest in Cartooning: Cartoonists and Editors Look at Ethics.

    ERIC Educational Resources Information Center

    Riffe, Daniel; And Others

    A study examined differences between political cartoonists and op-ed page editors on both traditional ethical issues (such as conflicts of interest) and the special, style-related concerns of editorial cartoonists. Hypotheses proposed were that editors and cartoonists (1) would condemn "cloning" or copying, reflecting an ethical principle…

  10. 29 CFR 793.11 - Combination announcer, news editor and chief engineer.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Combination announcer, news editor and chief engineer. 793...)(9) OF THE FAIR LABOR STANDARDS ACT Requirements for Exemption § 793.11 Combination announcer, news... as a news editor. In such cases, the primary employment test under the section 13(b)(9)...

  11. Adolescent Sexual Initiation through the Lens of Letters to the Editor Published in Polish Teenage Magazines

    ERIC Educational Resources Information Center

    Kopacz, Marek S.; Bajka-Kopacz, Aleksandra

    2012-01-01

    Almost all teenage magazines invite readers to submit questions concerning relationships, published as letters to the editor, popularly called "advice columns," often containing explicit questions about sexuality. This study aims to examine, firstly, how themes related to sexual initiation are presented in letters to the editor published in Polish…

  12. A "Situational" and "Coorientational" Measure of Specialized Magazine Editors' Perceptions of Readers.

    ERIC Educational Resources Information Center

    Jeffers, Dennis W.

    A study was undertaken of specialized magazine editors' perceptions of audience characteristics as well as the perceived role of their publications. Specifically, the study examines the relationship between the editors' perceptions of reader problem recognition, level of involvement, constraint recognition, and possession of reference criteria and…

  13. The Editor and Publisher as Public Official: The Ultimate Conflict of Interest.

    ERIC Educational Resources Information Center

    Sneed, Don

    A fifteen-item Likert scale and indepth personal interviews were used to collect data in a study that examined whether five individuals who held both the role of editor and public official were perceived as able to perform in a socially responsible manner as editors of their community newspapers in their estimation and in the estimation of a…

  14. One-pot synthesis of (-)-oseltamivir and mechanistic insights into the organocatalyzed Michael reaction.

    PubMed

    Mukaiyama, Takasuke; Ishikawa, Hayato; Koshino, Hiroyuki; Hayashi, Yujiro

    2013-12-23

    The one-pot sequential synthesis of (-)-oseltamivir has been achieved without evaporation or solvent exchange in 36% yield over seven reactions. The key step was the asymmetric Michael reaction of pentan-3-yloxyacetaldehyde with (Z)-N-2-nitroethenylacetamide, catalyzed by a diphenylprolinol silyl ether. The use of a bulky O-silyl-substituted diphenylprolinol catalyst, chlorobenzene as a solvent, and HCO2 H as an acid additive, were key to produce the first Michael adduct in both excellent yield and excellent diastereo- and enantioselectivity. Investigation into the effect of acid demonstrated that an acid additive accelerates not only the E-Z isomerization of the enamines derived from pentan-3-yloxyacetaldehyde with diphenylprolinol silyl ether, but also ring opening of the cyclobutane intermediate and the addition reaction of the enamine to (Z)-N-2-nitroethenylacetamide. The transition-state model for the Michael reaction of pentan-3-yloxyacetaldehyde with (Z)-N-2-nitroethenylacetamide was proposed by consideration of the absolute configuration of the major and minor isomers of the Michael product with the results of the Michael reaction of pentan-3-yloxyacetaldehyde with phenylmaleimide and naphthoquinone.

  15. THE NEW ONLINE METADATA EDITOR FOR GENERATING STRUCTURED METADATA

    SciTech Connect

    Devarakonda, Ranjeet; Shrestha, Biva; Palanisamy, Giri; Hook, Leslie A; Killeffer, Terri S; Boden, Thomas A; Cook, Robert B; Zolly, Lisa; Hutchison, Viv; Frame, Mike; Cialella, Alice; Lazer, Kathy

    2014-01-01

    Nobody is better suited to describe data than the scientist who created it. This description about a data is called Metadata. In general terms, Metadata represents the who, what, when, where, why and how of the dataset [1]. eXtensible Markup Language (XML) is the preferred output format for metadata, as it makes it portable and, more importantly, suitable for system discoverability. The newly developed ORNL Metadata Editor (OME) is a Web-based tool that allows users to create and maintain XML files containing key information, or metadata, about the research. Metadata include information about the specific projects, parameters, time periods, and locations associated with the data. Such information helps put the research findings in context. In addition, the metadata produced using OME will allow other researchers to find these data via Metadata clearinghouses like Mercury [2][4]. OME is part of ORNL s Mercury software fleet [2][3]. It was jointly developed to support projects funded by the United States Geological Survey (USGS), U.S. Department of Energy (DOE), National Aeronautics and Space Administration (NASA) and National Oceanic and Atmospheric Administration (NOAA). OME s architecture provides a customizable interface to support project-specific requirements. Using this new architecture, the ORNL team developed OME instances for USGS s Core Science Analytics, Synthesis, and Libraries (CSAS&L), DOE s Next Generation Ecosystem Experiments (NGEE) and Atmospheric Radiation Measurement (ARM) Program, and the international Surface Ocean Carbon Dioxide ATlas (SOCAT). Researchers simply use the ORNL Metadata Editor to enter relevant metadata into a Web-based form. From the information on the form, the Metadata Editor can create an XML file on the server that the editor is installed or to the user s personal computer. Researchers can also use the ORNL Metadata Editor to modify existing XML metadata files. As an example, an NGEE Arctic scientist use OME to register

  16. In Situ Observation of Thiol Michael Addition to a Reversible Covalent Drug in a Crystalline Sponge.

    PubMed

    Duplan, Vincent; Hoshino, Manabu; Li, Wei; Honda, Tadashi; Fujita, Makoto

    2016-04-11

    A reversible Michael addition reaction between thiol nucleophiles and cyanoenones has been previously postulated to be the mechanism-of-action of a new family of reversible covalent drugs. However, the hypothetical Michael adducts in this mechanism have only been detected by spectroscopic methods in solution. Herein, the crystallographic observation of reversible Michael addition with a potent cyanoenone drug candidate by means of the crystalline-sponge method is reported. After inclusion of the cyanoenone substrate, the sponge crystal was treated with a thiol solution. Subsequent crystallographic analysis confirmed the single-crystal-to-single-crystal transformation of the substrate into the impermanent Michael adduct.

  17. X-24B with Test Pilot Michael V. Love

    NASA Technical Reports Server (NTRS)

    1973-01-01

    This photo shows Air Force Lieutenant Colonel Michael V. Love in front of the X-24B lifting-body research vehicle at Edwards Air Force Base in 1973. Love was assigned as a project pilot on the joint NASA-USAF X-24B Lifting Body flight test program at the NASA Flight Research Center. He made a total of 12 flights in the plane from October 4, 1973 until July 15, 1975. Love flew it to a speed of Mach 1.76 on October 25, 1974, a record for the X-24B. Love attended the USAF Test Pilot School and remained as an instructor there from 1969 through 1971. He was a test pilot at Edwards when assigned to fly to the X-24B. Love was a combat veteran of Vietnam and was awarded the Distinguished Flying Cross with two Oak Leaf clusters. Love perished while attempting an emergency landing in an RF-4C on March 1, 1976. The X-24B was the last aircraft to fly in the Dryden Flight Research Center's manned lifting body program. The X-24 was one of a group of lifting bodies flown by the NASA Flight Research Center (now Dryden Flight Research Center), Edwards, California, in a joint program with the U.S. Air Force at Edwards Air Force Base from 1963 to 1975. The lifting bodies were used to demonstrate the ability of pilots to maneuver and safely land wingless vehicles designed to fly back to Earth from space and be landed like an airplane at a predetermined site. Lifting bodies' aerodynamic lift, essential to flight in the atmosphere, was obtained from their shape. The addition of fins and control surfaces allowed the pilots to stabilize and control the vehicles and regulate their flight paths. Built by Martin Aircraft Company, Maryland, for the U.S. Air Force, the X-24A was a bulbous vehicle shaped like a teardrop with three vertical fins at the rear for directional control. It weighed 6,270 pounds, was 24.5 feet long and 11.5 feet wide (measuring just the fuselage, not the distance between the tips of the outboard fins). Its first unpowered glide flight was on April 17, 1969, with Air

  18. The Best Stylists: A Survey of Editors, and Implications for the Teaching of Style in Freshman Composition Courses.

    ERIC Educational Resources Information Center

    Spigelmire, Lynne

    A survey of 112 editors from magazines, newspapers, and publishing houses was conducted to obtain their judgments about prose style, the best prose stylists, and representative works by those stylists. Of the 112 editors surveyed, only 22 responded with useful data. The results indicated very little consensus among editors, and almost no…

  19. The New Online Metadata Editor for Generating Structured Metadata

    NASA Astrophysics Data System (ADS)

    Devarakonda, R.; Shrestha, B.; Palanisamy, G.; Hook, L.; Killeffer, T.; Boden, T.; Cook, R. B.; Zolly, L.; Hutchison, V.; Frame, M. T.; Cialella, A. T.; Lazer, K.

    2014-12-01

    Nobody is better suited to "describe" data than the scientist who created it. This "description" about a data is called Metadata. In general terms, Metadata represents the who, what, when, where, why and how of the dataset. eXtensible Markup Language (XML) is the preferred output format for metadata, as it makes it portable and, more importantly, suitable for system discoverability. The newly developed ORNL Metadata Editor (OME) is a Web-based tool that allows users to create and maintain XML files containing key information, or metadata, about the research. Metadata include information about the specific projects, parameters, time periods, and locations associated with the data. Such information helps put the research findings in context. In addition, the metadata produced using OME will allow other researchers to find these data via Metadata clearinghouses like Mercury [1] [2]. Researchers simply use the ORNL Metadata Editor to enter relevant metadata into a Web-based form. How is OME helping Big Data Centers like ORNL DAAC? The ORNL DAAC is one of NASA's Earth Observing System Data and Information System (EOSDIS) data centers managed by the ESDIS Project. The ORNL DAAC archives data produced by NASA's Terrestrial Ecology Program. The DAAC provides data and information relevant to biogeochemical dynamics, ecological data, and environmental processes, critical for understanding the dynamics relating to the biological components of the Earth's environment. Typically data produced, archived and analyzed is at a scale of multiple petabytes, which makes the discoverability of the data very challenging. Without proper metadata associated with the data, it is difficult to find the data you are looking for and equally difficult to use and understand the data. OME will allow data centers like the ORNL DAAC to produce meaningful, high quality, standards-based, descriptive information about their data products in-turn helping with the data discoverability and

  20. A general overview of the organocatalytic intramolecular aza-Michael reaction.

    PubMed

    Sánchez-Roselló, María; Aceña, José Luis; Simón-Fuentes, Antonio; del Pozo, Carlos

    2014-11-01

    The organocatalytic intramolecular aza-Michael reaction gives access to enantiomerically enriched nitrogen-containing heterocycles in a very simple manner. Enals, enones, conjugated esters and nitro olefins have been employed as Michael acceptors, while moderate nitrogen nucleophiles such as sulphonamides, carbamates and amides have been shown to be appropriate Michael donors in this type of reaction. Additionally, the process has been performed under both covalent and non-covalent catalysis, with diaryl prolinols, imidazolidinones, thioureas and chiral binol phosphoric acids being the most frequently used catalysts. The level of efficiency reached with this protocol is demonstrated by the implementation of numerous tandem processes, as well as the total synthesis of several natural products.

  1. Michael addition reactions for the modification of gold nanoparticles facilitated by hyperbaric conditions.

    PubMed

    Hartlen, Kurtis D; Ismaili, Hossein; Zhu, Jun; Workentin, Mark S

    2012-01-10

    The chemical interfacial modification of organic solvent soluble 2.4 ± 0.5 nm maleimide-modified monolayer protected gold nanoparticles (2-C(12)AuNPs) with primary or secondary amines via Michael addition reactions is demonstrated. Michael addition reactions between 2-C(12)AuNPs and primary or secondary amines at ambient temperature and pressure and under the conditions where the AuNP is soluble and stable are possible albeit sluggish, often taking days to weeks to go to completion. The rates and efficacies of the these same reactions are drastically increased at hyperbaric pressure conditions (11 000 atm) with no observed adverse effect to the gold nanoparticle stability. The resulting Michael addition adducts (3-C(12)AuNPs) formed from 2-C(12)AuNPs and the corresponding amines were characterized by TEM and by comparison of the (1)H NMR spectra of the 3-C(12)AuNPs with those of model reactions of the same amines with N-dodecylmaleimide, 2. The Michael addition reactions occur more readily with 2 rather than 2-C(12)AuNPs, consistent with the local environment of the latter imposing additional steric or other barriers to the reaction. The use of hyperbaric conditions makes the reaction of the organic solvent soluble 2-C(12)AuNP via Michael addition a viable interfacial modification process that is otherwise impractical. The results also suggest that it is a useful protocol for facilitating Michael addition reactions generally in solution at low temperatures.

  2. Training the unseasoned technical writer-editor: From the trainee's perspective

    SciTech Connect

    Gibbs, B.R.

    1991-01-01

    Many unseasoned technical writer-editors who are not adequately trained may become seasoned inadequately trained technical writer-editors. This problem can occur when a trainee is involved in an ineffective training program, but it can be alleviated by the trainer's assessing the unseasoned writer's talents, becoming involved with the trainee's growth in writing and editing skills, and helping him to visualize his potential as a technical writer-editor. Assessment, support, mentoring, and nurturing are important elements in the trainee's growth process and in any good training or internship program. 1 ref.

  3. [Michael Lazarevich Gershanovich--one of the founders of cancer chemotherapy in Russia].

    PubMed

    Semiglazova, T Iu; Filatova, L V; Stukov, A N

    2014-01-01

    Michael Lazarevich Gershanovich was born 90 years ago. He has made a significant contribution to foundation and development of chemotherapy for malignant tumors. Doctor of Medical Sciences, Professor, Laureate of the State Prize of the Russian Federation, Honored Scientist of the Russian Federation, Academician of the Russian Academy of Natural Sciences, a member of the Editorial Board of the Journal "Problems in Oncology" ("Voprosy Onkologii), member of the World Club of Petersburgians, a retired lieutenant-colonel Michael Lazarevich, until his last day (16.12.2013), was the head of the Department of Medical Oncology of the N.N.Petrov Research Institute of Oncology, St. Petersburg. PMID:25552077

  4. Michael addition/pericyclization/rearrangement--a multicomponent strategy for the synthesis of substituted resorcinols.

    PubMed

    Liu, Yu; Doyle, Michael P

    2012-08-21

    The combination of methyl 3,7-dioxo-2-diazo-4-octenoate from the zinc triflate catalyzed Mukaiyama-Michael reaction of methyl 3-tert-butylsilyloxy-2-diazobutenoate and 4-methoxy-3-buten-2-one with Michael acceptors (methyl vinyl ketone, N-phenylmaleimide, β-nitrovinylarenes) in the presence of a catalytic amount of base provides convenient access to highly substituted resorcinol derivatives. This transformation is achieved in an efficient one-pot multi-component transformation by the sequential addition of the reagents.

  5. Copper-catalyzed asymmetric conjugate addition of organometallic reagents to extended Michael acceptors

    PubMed Central

    Schmid, Thibault E; Drissi-Amraoui, Sammy; Crévisy, Christophe; Baslé, Olivier

    2015-01-01

    Summary The copper-catalyzed asymmetric conjugate addition (ACA) of nucleophiles onto polyenic Michael acceptors represents an attractive and powerful methodology for the synthesis of relevant chiral molecules, as it enables in a straightforward manner the sequential generation of two or more stereogenic centers. In the last decade, various chiral copper-based catalysts were evaluated in combination with different nucleophiles and Michael acceptors, and have unambiguously demonstrated their usefulness in the control of the regio- and enantioselectivity of the addition. The aim of this review is to report recent breakthroughs achieved in this challenging field. PMID:26734090

  6. Copper-catalyzed asymmetric conjugate addition of organometallic reagents to extended Michael acceptors.

    PubMed

    Schmid, Thibault E; Drissi-Amraoui, Sammy; Crévisy, Christophe; Baslé, Olivier; Mauduit, Marc

    2015-01-01

    The copper-catalyzed asymmetric conjugate addition (ACA) of nucleophiles onto polyenic Michael acceptors represents an attractive and powerful methodology for the synthesis of relevant chiral molecules, as it enables in a straightforward manner the sequential generation of two or more stereogenic centers. In the last decade, various chiral copper-based catalysts were evaluated in combination with different nucleophiles and Michael acceptors, and have unambiguously demonstrated their usefulness in the control of the regio- and enantioselectivity of the addition. The aim of this review is to report recent breakthroughs achieved in this challenging field.

  7. Aza-Michael Mono-addition Using Acidic Alumina under Solventless Conditions.

    PubMed

    Bosica, Giovanna; Abdilla, Roderick

    2016-06-22

    Aza-Michael reactions between primary aliphatic and aromatic amines and various Michael acceptors have been performed under environmentally-friendly solventless conditions using acidic alumina as a heterogeneous catalyst to selectively obtain the corresponding mono-adducts in high yields. Ethyl acrylate was the main acceptor used, although others such as acrylonitrile, methyl acrylate and acrylamide were also utilized successfully. Bi-functional amines also gave the mono-adducts in good to excellent yields. Such compounds can serve as intermediates for the synthesis of anti-cancer and antibiotic drugs.

  8. Pyrrolidinyl-sulfamide derivatives as a new class of bifunctional organocatalysts for direct asymmetric Michael addition of cyclohexanone to nitroalkenes.

    PubMed

    Chen, Jia-Rong; Fu, Liang; Zou, You-Quan; Chang, Ning-Jie; Rong, Jian; Xiao, Wen-Jing

    2011-07-21

    A series of chiral pyrrolidinyl-sulfamide derivatives have been identified as efficient bifunctional organocatalysts for the direct Michael addition of cyclohexanone to a wide range of nitroalkenes. The desired Michael adducts were obtained in high chemical yields and excellent stereoselectivities (up to 99/1 dr and 95% ee).

  9. Decarboxylative 1,4-Addition of α-Oxocarboxylic Acids with Michael Acceptors Enabled by Photoredox Catalysis.

    PubMed

    Wang, Guang-Zu; Shang, Rui; Cheng, Wan-Min; Fu, Yao

    2015-10-01

    Enabled by iridium photoredox catalysis, 2-oxo-2-(hetero)arylacetic acids were decarboxylatively added to various Michael acceptors including α,β-unsaturated ester, ketone, amide, aldehyde, nitrile, and sulfone at room temperature. The reaction presents a new type of acyl Michael addition using stable and easily accessible carboxylic acid to formally generate acyl anion through photoredox-catalyzed radical decarboxylation. PMID:26366608

  10. 78 FR 66970 - In the Matter of Michael J. Buhrman; Order Prohibiting Involvement in NRC-Licensed Activities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... be filed in accordance with the NRC E-Filing rule (72 FR 49139, August 28, 2007). The E-Filing... COMMISSION In the Matter of Michael J. Buhrman; Order Prohibiting Involvement in NRC-Licensed Activities (Effective Immediately) I. Michael J. Buhrman was formerly employed as a senior reactor operator (SRO) at...

  11. 76 FR 44901 - Californians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. California Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-27

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Californians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v..., Californians for Renewable Energy, Inc. (CARE), acting on behalf of its members, Michael E. Boyd, and Robert...

  12. 78 FR 6851 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-31

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS AFFAIRS Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program....'' SUPPLEMENTARY INFORMATION: Title: Patient Satisfaction Survey Michael E. DeBakey Home Care Program, VA Form...

  13. 77 FR 40878 - Californians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey, v. California Public...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Californians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey... Utility Regulatory Policies Act of 1978 (PURPA), Californians for Renewable Energy, Inc., Michael E....

  14. 76 FR 624 - Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-05

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF VETERANS AFFAIRS Proposed Information Collection (Patient Satisfaction Survey Michael E. DeBakey Home Care Program.... 2900-New (VA Form 10-0476).'' SUPPLEMENTARY INFORMATION: Title: Patient Satisfaction Survey Michael...

  15. Science publishing: A day in the life of an APS editor

    NASA Astrophysics Data System (ADS)

    Thomas, Katherine

    2015-03-01

    I will share my experience in working as an editor for a scholarly journal. The talk will include information on my career path, the skills and qualifications needed, and give insight into my day-to-day activities

  16. Uniform requirements for manuscripts submitted to biomedical journals. International Committee of Medical Journal Editors.

    PubMed Central

    1994-01-01

    In the 13 years since it was first published the "Uniform requirements for manuscripts submitted to biomedical journals" (the Vancouver style), developed by the International Committee of Medical Journal Editors, has been widely accepted by both authors and editors; over 400 journals have stated that they will consider manuscripts that conform to its requirements. This is the fourth edition of the "Uniform requirements." PMID:8287338

  17. EDITORIAL: Message from the new Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Dendy, R.

    2005-01-01

    On 1 January 2005 I become Editor-in-Chief of Plasma Physics and Controlled Fusion. I look forward to assisting contributors, referees and the Board in maintaining the high standards of this international journal, whose bibliometric impact factor has consistently matched or exceeded that of other journals in the field. The robust, good health of Plasma Physics and Controlled Fusion reflects that of its user communities. With a decision to proceed to the construction of ITER apparently imminent, magnetic confinement fusion research is preparing to take a major step forwards. A new generation of laser-plasma interaction facilities for inertial fusion research is also rising at key sites around the world. Technical progress in our field is underpinned by scientific excellence, and the publication of results in Plasma Physics and Controlled Fusion will, I hope, continue to play its part. The journal will continue to offer the benefits of refereeing by two experts, combined with the rapid turnaround achieved by the highly efficient editorial office at the Institute of Physics Publishing in Bristol. Looking elsewhere, there may be opportunities for gentle incremental broadening of the scientific scope of the journal, in the medium term. One looks in particular to those branches of plasma physics that, in recent years, have become more strongly represented in the series of conferences organized by the Plasma Physics Division of the European Physical Society. The recent special issue of Plasma Physics and Controlled Fusion (Plasma Phys. Control. Fusion 46 (2004) B1--592) provides an indication. Finally, it is a pleasure to thank my predecessor, Professor Ian Hutchinson of the Massachusetts Institute of Technology, for handing on his role with the journal in such promising condition.

  18. Q & A with Ed Tech Leaders: Interview with J. Michael Spector

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.; Fulgham, Susan M.

    2015-01-01

    J. Michael Spector's academic preparation was in philosophy--epistemology and logic, primarily. His dissertation was on skepticism in modern philosophy, and that led him to a deep-seated appreciation for classical skepticism. The word "skeptic" is derived from the Greek word "skepsis," which means investigation. While the…

  19. Organocatalytic Michael addition/intramolecular Julia-Kocienski olefination for the preparation of nitrocyclohexenes.

    PubMed

    Rodrigo, Eduardo; García Ruano, José Luis; Cid, M Belén

    2013-11-01

    An asymmetric organocatalytic [3 + 3] annulation strategy based on a Michael addition/intramolecular Julia-Kocienski olefination sequence has been developed for the synthesis of 4-substituted-5-nitrocyclohex-1-ene compounds. The strategy is an alternative to the direct reluctant enantioselective Diels-Alder approach. The potential of the methodology has been demonstrated with a concise enantioselective formal synthesis of trandolapril.

  20. Design of Reversible, Cysteine-Targeted Michael Acceptors Guided by Kinetic and Computational Analysis

    PubMed Central

    2015-01-01

    Electrophilic probes that covalently modify a cysteine thiol often show enhanced pharmacological potency and selectivity. Although reversible Michael acceptors have been reported, the structural requirements for reversibility are poorly understood. Here, we report a novel class of acrylonitrile-based Michael acceptors, activated by aryl or heteroaryl electron-withdrawing groups. We demonstrate that thiol adducts of these acrylonitriles undergo β-elimination at rates that span more than 3 orders of magnitude. These rates correlate inversely with the computed proton affinity of the corresponding carbanions, enabling the intrinsic reversibility of the thiol-Michael reaction to be tuned in a predictable manner. We apply these principles to the design of new reversible covalent kinase inhibitors with improved properties. A cocrystal structure of one such inhibitor reveals specific noncovalent interactions between the 1,2,4-triazole activating group and the kinase. Our experimental and computational study enables the design of new Michael acceptors, expanding the palette of reversible, cysteine-targeted electrophiles. PMID:25153195

  1. The Journey Is the Film Is the Journey: Michael Winterbottom's "In This World"

    ERIC Educational Resources Information Center

    Farrier, David

    2008-01-01

    This essay examines Michael Winterbottom's 2002 film "In This World," which follows the journey of two Afghan migrants from Peshawar to London. Winterbottom's preparation involved travelling from London to Peshawar and then in reverse overland as far as Istanbul; he then returned to Peshawar and filmed the same journey using two non-professional…

  2. Vision and Elusiveness in Philosophy of Education: R. S. Peters on the Legacy of Michael Oakeshott

    ERIC Educational Resources Information Center

    Williams, Kevin

    2009-01-01

    Despite his elusiveness on important issues, there is much in Michael Oakeshott's educational vision that Richard Peters quite rightly wishes to endorse. The main aim of this essay is, however, to consider Peters' justifiable critique of three features of Oakeshott's work. These are (1) the rigidity of his distinction between vocational and…

  3. Neuroscientific Investigator of High Mathematical Ability: An Interview with Michael W. O'Boyle

    ERIC Educational Resources Information Center

    Kalbfleisch, M. Layne

    2008-01-01

    This article presents an interview with Michael W. O'Boyle, a neuroscientific investigator of high mathematical ability. O'Boyle is a professor in the Department of Human Development and Family Studies, Texas Tech University, and Adjunct Professor of Pharmacology and Neuroscience, School of Medicine, Texas Tech University Health Sciences Center.…

  4. A tribute to Michael R. Raupach for contributions to aeolian fluid dynamics

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Since the early work of Bagnold in the 1940s, aeolian research has grown to become a major integral part of earth-system studies. Many individuals have contributed to this development, and Dr. Michael R. Raupach (MR2, 1950 – 2015) was one of the most outstanding. MR2 worked for about a decade (1985 ...

  5. Michael Pressley's Contributions to the History and Future of Strategies Research

    ERIC Educational Resources Information Center

    Harris, Karen R.; Alexander, Patricia; Graham, Steve

    2008-01-01

    The history of strategies research during the past quarter century has been a story of significant conceptualizations and reconceptualizations regarding the nature, development, and teaching of cognitive and metacognitive strategies. Theoretical models, empirical research, and discussions contributed by Michael Pressley have been central to…

  6. An Interview with Michael Horn: Blending Education for High-Octane Motivation

    ERIC Educational Resources Information Center

    Patterson, Gregory A.

    2012-01-01

    Blended learning holds the potential of improving the way we educate students and of making them more motivated. Blended education--the melding of information technology based distance learning with school attendance--is perhaps the best way to educate students for 21st century skills, says Michael Horn in a "Kappan" interview. Horn points out…

  7. The power of virtual integration: an interview with Dell Computer's Michael Dell. Interview by Joan Magretta.

    PubMed

    Dell, M

    1998-01-01

    Michael Dell started his computer company in 1984 with a simple business insight. He could bypass the dealer channel through which personal computers were then being sold and sell directly to customers, building products to order. Dell's direct model eliminated the dealer's markup and the risks associated with carrying large inventories of finished goods. In this interview, Michael Dell provides a detailed description of how his company is pushing that business model one step further, toward what he calls virtual integration. Dell is using technology and information to blur the traditional boundaries in the value chain between suppliers, manufacturers, and customers. The individual pieces of Dell's strategy--customer focus, supplier partnerships, mass customization, just-in-time manufacturing--may be all be familiar. But Michael Dell's business insight into how to combine them is highly innovative. Direct relationships with customers create valuable information, which in turn allows the company to coordinate its entire value chain back through manufacturing to product design. Dell describes how his company has come to achieve this tight coordination without the "drag effect" of ownership. Dell reaps the advantages of being vertically integrated without incurring the costs, all the while achieving the focus, agility, and speed of a virtual organization. As envisioned by Michael Dell, virtual integration may well become a new organizational model for the information age. PMID:10177868

  8. The power of virtual integration: an interview with Dell Computer's Michael Dell. Interview by Joan Magretta.

    PubMed

    Dell, M

    1998-01-01

    Michael Dell started his computer company in 1984 with a simple business insight. He could bypass the dealer channel through which personal computers were then being sold and sell directly to customers, building products to order. Dell's direct model eliminated the dealer's markup and the risks associated with carrying large inventories of finished goods. In this interview, Michael Dell provides a detailed description of how his company is pushing that business model one step further, toward what he calls virtual integration. Dell is using technology and information to blur the traditional boundaries in the value chain between suppliers, manufacturers, and customers. The individual pieces of Dell's strategy--customer focus, supplier partnerships, mass customization, just-in-time manufacturing--may be all be familiar. But Michael Dell's business insight into how to combine them is highly innovative. Direct relationships with customers create valuable information, which in turn allows the company to coordinate its entire value chain back through manufacturing to product design. Dell describes how his company has come to achieve this tight coordination without the "drag effect" of ownership. Dell reaps the advantages of being vertically integrated without incurring the costs, all the while achieving the focus, agility, and speed of a virtual organization. As envisioned by Michael Dell, virtual integration may well become a new organizational model for the information age.

  9. What Work Do the Concepts of "Language" and "Literature" Do for Michael Rosenak?

    ERIC Educational Resources Information Center

    Levisohn, Jon A.

    2014-01-01

    Michael Rosenak uses the twin metaphors of "language" and "literature," borrowed from Oakeshott and Peters, to argue that the goal of education is initiation into a language. This goal transcends the study of literature in that language. It includes, as well, the development of the capacity both to critique literature and to…

  10. Michael Eric Dyson: A Scholar and a Hip-Hop Preacher.

    ERIC Educational Resources Information Center

    Fletcher, Michael A.

    2000-01-01

    Introduces Michael Eric Dyson, an African American man who grew up in the ghetto and eventually received a PhD from Princeton University. Today, he is a professor at DePaul University, the author of a radically revisionist new biography of Martin Luther King, Jr., a lecturer and talk show guest, a Baptist preacher, and a self-styled hip-hop…

  11. Michael Peters' Lyotardian Account of Postmodernism and Education: Some Epistemic Problems and Naturalistic Solutions

    ERIC Educational Resources Information Center

    Clark, John A.

    2006-01-01

    Postmodernism has established a significant hold in educational thought and some of the most important ideas are to be found in the writings of Michael Peters. This paper examines his postmodern stance and use of Lyotard's account of knowledge, and from a naturalist point of view raises a number of objections centred on science as a metanarrative,…

  12. Little Mosie from the Margaree: A Biography of Moses Michael Coady.

    ERIC Educational Resources Information Center

    Welton, Michael R.

    This book examines the life of the Reverend Moses Michael Coady (1890-1959), a Roman Catholic priest who led the Antigonish Movement. During the Antigonish Movement, residents of the small maritime town of Antigonish, Nova Scotia, worked to achieve a nonviolent alternative to communism and fascism and to effect the social and economic…

  13. From Gouldner to Gramsci: The Making of Michael Apple's "Ideology and Curriculum"

    ERIC Educational Resources Information Center

    Gottesman, Isaac

    2012-01-01

    Michael Apple's "Ideology and Curriculum", published in 1979, helped initiate a broad turn in the field of education in the United States to Marxist thought as a lens through which to analyze the relationship between school and society. This classic text continues to inform scholarship in the field. While "Ideology" has received considerable…

  14. 76 FR 21406 - Michael J. Aruta, M.D.; Decision and Order

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-15

    ... Decision of the Administrative Law Judge (76 FR 19420). In preparing the document for publication, the... at 76 FR 19420 under the third column. Dated: April 8, 2011. Michele M. Leonhart, Administrator... Enforcement Administration Michael J. Aruta, M.D.; Decision and Order ACTION: Correction. On Thursday, April...

  15. Asymmetric Michael addition reactions of nitroalkanes to 2-furanones catalyzed by bifunctional thiourea catalysts.

    PubMed

    Bai, Zhushuang; Ji, Ling; Ge, Zemei; Wang, Xin; Li, Runtao

    2015-05-21

    The first bifunctional thiourea catalyzed asymmetric Michael addition reactions of nitroalkanes to 2-furanones are described. The highly functionalized γ-lactones with two or three consecutive stereogenic carbons were obtained in high yields (up to 99%), high diastereoselectivities (up to >20 : 1 dr) and enantioselectivities (up to >99% ee).

  16. On Not Abolishing Faith Schools: A Response to Michael Hand and H. Siegel

    ERIC Educational Resources Information Center

    Groothuis, Douglas

    2004-01-01

    This article finds Michael's Hand's argument for the abolition of faith schools to be deficient because key premises of his argument seem false. I argue that the concept of knowledge that Hand employs in arguing that no religious proposition is known to be true is overly strict. I reject Siegel's attempt to amend Hand's argument to make it…

  17. Training and Mastery of Techniques in Wittgenstein's Later Philosophy: A Response to Michael Luntley

    ERIC Educational Resources Information Center

    Stickney, Jeff

    2008-01-01

    Responding to Michael Luntley's article, "Learning, Empowerment and Judgement," the author shows he cannot successfully make the following three moves: (1) dissolve the analytic distinction between learning by training and learning by reasoning, while advocating the latter; (2) diminish the role of training in Wittgenstein's philosophy, nor…

  18. Irish Education for the 21st Century. Michael Enright Commemorative Project.

    ERIC Educational Resources Information Center

    Ward, Noel, Ed.; Dooney, Triona, Ed.

    The essays in this collection contribute to the ongoing discussion about the state of Irish education on the threshold of a new century. The various contributors examine issues that will be priorities for education planners in Ireland. These essays have been collected as a tribute to Irish educator and politician Michael Enright. The essays are:…

  19. Broadening the Debate: Comments on Michael J. Feuer's "Moderating the Debate"

    ERIC Educational Resources Information Center

    Robertson, Emily

    2009-01-01

    In "Moderating the Debate: Rationality and the Promise of American Education", Michael Feuer argues that insights from cognitive science and the theory of bounded rationality can help us understand why educational policy makers overreach in seeking optimal solutions to educational problems. In this essay, Emily Robertson argues that cognitive…

  20. C. P. Snow's "The Two Cultures": Michael Polanyi's Response and Context

    ERIC Educational Resources Information Center

    Jacobs, Struan

    2011-01-01

    C. P. Snow's "The Two Cultures" controversially contrasted science and literature, suggesting that neither scientists nor literary intellectuals have much in common with, and seldom bother speaking to, the other. Responding to Snow, Michael Polanyi argued that specialization has made modern culture, not twofold but manifold. In his major work,…

  1. Michael E. Barnes: Award for Distinguished Professional Contributions to Institutional Practice

    ERIC Educational Resources Information Center

    American Psychologist, 2012

    2012-01-01

    Presents a short biography on the winner of the American Psychological Association's Award for Distinguished Professional Contributions to Institutional Practice. The 2012 winner is Michael E. Barnes for his pioneering leadership, dedication, and distinguished contributions to juvenile justice. As chief psychologist of the Superior Court of the…

  2. A Response to Michael W. Apple's "Theory, Research, and the Critical Scholar/Activist"

    ERIC Educational Resources Information Center

    Leonardo, Zeus

    2010-01-01

    Michael Apple's prescient review of Anyon et al.'s "Theory and Educational Research" reminds the educational community of the importance of purpose. In his own work, he has been consistent in--actually, insistent on--emphasizing the struggle over political projects. This is not an issue concerning only the Left as the scapegoat for the disparaging…

  3. Learning to Lose: Rurality, Transience, and Belonging (A Companion to Michael Corbett)

    ERIC Educational Resources Information Center

    Kelly, Ursula A.

    2009-01-01

    In this commentary, the author focuses on the central point of Michael Corbett's book "Learning to Leave". Education, and in particular what is called "rural" education, is premised on loss. This loss is often not fully articulated, but it is deep and abiding. It is registered in efforts to stop the flow of people and resources, to resist…

  4. The Benevolent Technocrat: Michael Dukakis' Strategy in the 1988 Presidential Debates.

    ERIC Educational Resources Information Center

    Herbeck, Dale A.

    Michael Dukakis lost the presidential campaign debates of 1988 (or at least failed to capitalize as much as he might have) because he understood the debates to be genuine debates. Consequently, Dukakis acted as a debater generating an image of himself as a "benevolent technocrat," which was an error. It must be pointed out that the presidential…

  5. Wolff-Michael Roth's passibility: at the limits of the constructivist metaphor: a book review

    NASA Astrophysics Data System (ADS)

    Brendel, Michelle

    2014-12-01

    Wolff-Michael Roth deconstructs the preeminent role conceded to constructivism in Science Education and demonstrates how we learn and know through pain, suffering, love or passion. This review explores his book "Passibility: At the Limits of the Constructivist Metaphor" through the eyes of an outsider to the world of science education.

  6. Why Do We Need a Philosophy of Education? The Forgotten Insights of Michael John Demiashkevich

    ERIC Educational Resources Information Center

    Senechal, Diana

    2010-01-01

    For many decades, American schools have been mired in jargon and confused values. A few exceptional books have shown the way through the thicket of educational ideas, policies, and practices. The work of Michael John Demiashkevich belongs to this set and offers a special philosophical perspective. In "An Introduction to the Philosophy of…

  7. Michael Shaffer, 6th July 1936 to 23rd March 2009: A heartfelt tribute

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Mr. Michael Shaffer, Retired Pyraloidea Curator, at the Natural History Museum, London, England, passed away on March 23, 2009. He was an acknowledged world expert on Pyraloidea, a group of agriculturally important moths. He was curator of the largest Pyraloidea type collection in the world, and a...

  8. Q & A with Ed Tech Leaders: Interview with Michael W. Allen

    ERIC Educational Resources Information Center

    Shaughnessy, Michael F.

    2014-01-01

    Michael W. Allen, the Chairman and CEO of Allen Interactions, is an architect of interactive multimedia learning and is recognized for his many insights, inventions, and presentations. With over 50 years of experience in e-learning, both in academic and corporate settings, he is known for his role in creating Authorware and overseeing the work of…

  9. Moral Education and Education in Altruism: Two Replies to Michael Hand

    ERIC Educational Resources Information Center

    White, John

    2016-01-01

    This article is a critical discussion of two recent papers by Michael Hand on moral education. The first is his "Towards a Theory of Moral Education", published in the "Journal of Philosophy of Education" in 2014 (Volume 48, Issue 4). The second is a chapter called "Beyond Moral Education?" in an edited book of new…

  10. "Raising Standards" or Reducing Aspirations and Opportunities Still Further? Michael Gove and Examination Reforms

    ERIC Educational Resources Information Center

    Allen, Martin

    2013-01-01

    Well before the examinations grade crisis of 2012, Michael Gove had set out clear intentions for reforming public examinations. Though he claimed to be improving examinations and assessment by replicating practices that took place in high-performing countries and thus improving the ability of the UK economy to "compete", this…

  11. Education, Philosophy and Politics: The Selected Works of Michael A. Peters. World Library of Educationalists

    ERIC Educational Resources Information Center

    Peters, Michael A.

    2012-01-01

    In the World Library of Educationalists series, international experts themselves compile career-long collections of what they judge to be their finest pieces--extracts from books, key articles, salient research findings, major theoretical and/practical contributions--so the world can read them in a single manageable volume. Michael A. Peters has…

  12. Schools as "Poetry-Friendly Places": Michael Rosen on Poetry in the Curriculum

    ERIC Educational Resources Information Center

    Xerri, Daniel

    2014-01-01

    This article explores the views of children's poet Michael Rosen in relation to poetry in education. It is based on an interview in which Rosen not only discusses the significance of encouraging young people to engage with poetry at school but also analyzes a number of threats to poetry's place in the English curriculum. This article…

  13. STS-34 Pilot Michael J. McCulley uses ARRIFLEX camera equipment

    NASA Technical Reports Server (NTRS)

    1989-01-01

    STS-34 Atlantis, Orbiter Vehicle (OV) 104, Pilot Michael J. McCulley squints while looking through ARRIFLEX camera eye piece during camera briefing at JSC. McCulley rests part of the camera on his shoulder as he operates it.

  14. Astronaut C. Michael Foale is briefed on use of Sky Genie

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Astronaut C. Michael Foale, STS-63 mission specialist, is briefed on the use of Sky Genie device by Karin L. Porter. The device would aid in emergency egress operations aboard a troubled Space Shuttle. Porter, an employee of Rockwell International, helps train astronauts in egress procedures at JSC's Shuttle mockup and integration laboratory.

  15. The Educational Philosophies of Mordecai Kaplan and Michael Rosenak: Surprising Similarities and Illuminating Differences

    ERIC Educational Resources Information Center

    Schein, Jeffrey; Caplan, Eric

    2014-01-01

    The thoughts of Mordecai Kaplan and Michael Rosenak present surprising commonalities as well as illuminating differences. Similarities include the perception that Judaism and Jewish education are in crisis, the belief that Jewish peoplehood must include commitment to meaningful content, the need for teachers to teach from a position of…

  16. Michael Faraday on the Learning of Science and Attitudes of Mind.

    ERIC Educational Resources Information Center

    Crawford, Elspeth

    1998-01-01

    Makes use of Michael Faraday's ideas on learning, focusing on his attitudes toward the unknowns of science and the development of an attitude that improves scientific decision making. This approach acknowledges that there is an inner struggle involved in facing unknowns. (DDR)

  17. Michael Oakeshott's Philosophy of Education and Its Implications for Instructional Design Theory and Practice.

    ERIC Educational Resources Information Center

    Tripp, Steven

    Michael Oakeshott, an English political philosopher, wrote extensively about education and how people learn political skills. Much of what he wrote may have interesting implications for instructional systems design. This paper is an explication of two aspects of Oakeshott's writings. The first deals with the nature of knowledge and its…

  18. Subjectivity and Cultural Adjustment in Mathematics Education: A Response to Wolff-Michael Roth

    ERIC Educational Resources Information Center

    Brown, Tony

    2012-01-01

    In this volume, Wolff-Michael Roth provides a critical but partial reading of Tony Brown's book "Mathematics Education and Subjectivity". The reading contrasts Brown's approach with Roth's own conception of subjectivity as derived from the work of Vygotsky, in which Roth aims to "reunite" psychology and sociology. Brown's book, however, focuses on…

  19. Report of the world association of medical editors: agenda for the future.

    PubMed

    2001-04-01

    During a 3-day meeting at Bellagio in January 2001, a group of 20 editors from 12 countries in 5 continents met to map out a strategy for the World Association of Medical Editors (WAME)'s continued development in the service of medical editors over the next several years. The group: 1) Developed a statement of principles on the standards of professionalism and responsibilities of editors (this statement will be posted on the Web site after electronic consultation with and comment by WAME editors); 2) Agreed to assess the extent to which these principles are reflected in practice and to explore barriers to their adoption, using data from a survey and focus groups; 3) Developed and outlined an on-line program for distance learning, targeted at new editors; 4) Planned for formal evaluation of the educational outreach program; and 5) Agreed to support regional initiatives to strengthen local editorial capacity. Underpinning all past and proposed future activities is the WAME Web site. The ambitious plans outlined above will require extensive development of the site, plans for which were made at the Bellagio meeting.

  20. Successful treatment of recalcitrant candidal intertrigo with Dr Michaels® (Fungatinex®) product family.

    PubMed

    Hercogovấ, J; Tirant, M; Bayer, P; Coburn, M; Donnelly, B; Kennedy, T; Gaibor, J; Arora, M; Clews, L; Fioranelli, M; Gianfaldoni, S; Chokoeva, A A; Tchernev, G; Wollina, U; Novotny, F; Roccia, M G; Maximov, G K; França, K; Lotti, T

    2016-01-01

    Candidal intertrigo is an infection of the skin caused by Candida albicans that typically occurs in opposing cutaneous or muco-cutaneous surfaces. Because Candidiasis requires a damaged and moist environment for infection, it typically occurs in areas of friction such as the skin folds of the body. Candidal intertrigo is often difficult to treat and results are often unsatisfactory. In addition, there is a lack of evidence-based literature supporting prevention and treatments for candidal intertrigo. The aim of the study was to evaluate the efficacy of Dr Michaels® (also branded as Fungatinex®) products in the treatment of fungal intertrigo, in 20 women and 2 men with a mean age of 72. Five patients (3 female and 2 male) had type 2 diabetes and 16 (14 female and 2 male) were obese. The patients were treated with Dr Michaels® (Fungatinex®) moisturising bar, topical ointment (twice daily application) and oral herbal formulation, PSC 200 two tablets twice daily with food. After 2 weeks of treatment, the lesions had mostly resolved in all patients with only slight erythema evident. After six weeks of treatment using the moisturising bar, topical ointment and oral herbal formulations from the Dr Michaels® (Fungatinex®) product family, the lesions had totally resolved in 18 patients, while 4 patients had to continue the therapeutic protocol for another 2 weeks. Our results demonstrate that the Dr Michaels® (Fungatinex®) complementary product family is efficacious in the treatment of recalcitrant candidal intertrigo. Furthermore, this study highlights that the Dr Michaels® (Fungatinex®) product family is fast-acting and well tolerated with no serious adverse events reported. These data have important implications for resistant cases of candidal intertrigo where traditional therapies have failed. PMID:27498664

  1. EDITORIAL: Greetings from the new Editor-in-Chief Greetings from the new Editor-in-Chief

    NASA Astrophysics Data System (ADS)

    Gardner, Jason S.

    2012-01-01

    As I begin my tenure as Editor-in-Chief of Journal of Physics: Condensed Matter (JPCM), I look upon this opportunity as both an honour and a real challenge. The journal is in great shape thanks to the work of my predecessors, Marshall Stoneham and David Ferry. The journal's solid reputation is based largely on the work these gentlemen have done over the past decade. The other main reason for the success of JPCM is the amazing staff in Bristol; keep up the good work, please. When discussing the journal with scientists from all corners of the globe, one thing is always mentioned—JPCM is a very reliable journal with well-written, high-quality papers, and a fast but rigorous peer-review process that provides fair, detailed and constructive referee reports for the benefit of authors. This is due almost entirely to our great authors and referees; we rely on them every day—thank you. As the new Editor-in-Chief I hope to continue to improve still further the journal's status in condensed matter science. As mentioned above, our reputation is excellent, but the reality is that we live in a world of bibliometrics and rankings. Over the past few years JPCM has been repositioned as a journal at the forefront of condensed matter physics, and the impact of the journal should increase further as a result of continued emphasis on commissioning in cutting-edge areas identified by the Editorial Board and the journal team. In addition to regular papers, JPCM has a number of other content streams that authors and readers can benefit from. Fast track communications (FTCs) offer exceptionally fast publication for work of the highest impact and urgency. By their select nature, FTCs benefit from personal treatment by the Editorial Board and the average receipt-to-first-decision time is just 11 days (the average receipt-to-publication time is just 45 days). Topical reviews in JPCM make the journal one of the most authoritative sources of review content for condensed matter physics

  2. EDITORIAL: Thank you and farewell from the Founding Editor

    NASA Astrophysics Data System (ADS)

    Baskes, Mike

    2005-07-01

    I have been involved with Modelling and Simulation in Materials Science and Engineering (MSMSE) from the very beginning when it was merely an idea, over 14 years ago, to the current journal that is well supported by the community. During my time as Editor there have been many changes in the journal, including the introduction of electronic submissions, web-based services and free printed colour where it is essential to the article, as well as completely free colour online. The journal has seen excellent growth in the number and quality of submissions and the number of articles published continues to rise, enabling us to expand the journal to eight issues in 2005. Web accesses and downloads have greatly surpassed even my wildest dreams. In my opinion, the emergence of MSMSE as a top materials modelling journal has confirmed the vision of Institute of Physics Publishing (IOPP) and the Executive Board that this area of science and engineering was ripe for a specialized journal. I feel that, having seen the journal through the early years and watched it grow into a successful arena for multidisciplinary materials research, it is now an appropriate time for me to hand over the reins. The journal has a great foundation for future growth and development and is supported by an excellent Editorial Board, who have given me a great deal of help and advice over the years. I feel sure that they will continue to support the journal when Bill Curtin, Brown University, takes over on 1 July 2005. Bill has the diverse experience in modelling at the atomic, dislocation, and continuum levels to lead the journal to new heights. Finally I would like to thank all of the readers, authors and referees who have greatly contributed to MSMSE over the years. Thank you for your support and help, and I hope you will continue to support the journal. Last, but not least, I would like to thank the staff at IOPP. Without their expert assistance, the journal could not have been as successful as it is

  3. CHAIRMEN'S PREFACE AND EDITORS' NOTE: Unification of Fundamental Interactions

    NASA Astrophysics Data System (ADS)

    Brink, Lars; Nilsson, Jan S.; Salomonson, Per; Skagerstam, Bo-Sture

    1987-01-01

    Vainshtein. We had hoped that the Nobel Symposium should be a signal for improved relations between East and West, but in this respect we failed. The Symposium was held in the small town of Marstrand, a summer resort on an island outside Göteborg. The idea was to have it relatively close to home and to show the participants perhaps the best part of the local nature. Another motive was to keep the participants semi-isolated to provide ample time for discussions. With the somewhat heavy programme we found that even so, the days were not long enough. This Symposium was the second Nobel Symposium on elementary particle physics. The first one, also organized by our group, was held in 1968. We hope and believe that the next one need not be awaited another 18 years! The Symposium was made possible by a generous grant from the Nobel Foundation. An additional grant from the Royal Swedish Academy of Sciences was also essential. A grant from Nordita made it possible to invite some ten Nordic observers. We also gratefully acknowledge help with the organization of the Symposium from the city of Goteborg, the city of Kungälv, Volvo, Skandinaviska Enskilda banken, Ericsson AB and IBM Sweden. We thank all the participants for all their efforts, to come to our remote part of the world, to give excellent talks, to write up their talks astonishingly quickly and to share with us so much of their knowledge and expertise. Last but not least we are indebted to the members of the organizing committee, members of the group and the secretarial staff. Goteborg, August 1986 Editors' NoteIn these Proceedings the lectures are given in the order of their oral presentation at the Symposium. Regrettably, a few contributors could not participate (V. Gribov, A. Linde, V. Ogievetsky, M. Shifman and A. M. Polyakov). Their contributions have been placed close to the end of the Proceedings. As these authors did not have the opportunity of correcting the proofs, responsibility for printing errors must rest with

  4. Highly Enantioselective Aza-Michael Reaction between Alkyl Amines and β-Trifluoromethyl β-Aryl Nitroolefins.

    PubMed

    Wang, Leming; Chen, Jiean; Huang, Yong

    2015-12-14

    The aza-Michael addition reaction is a vital transformation for the synthesis of functionalized chiral amines. Despite intensive research, enantioselective aza-Michael reactions with alkyl amines as the nitrogen donor have not been successful. We report the use of chiral N-heterocyclic carbenes (NHCs) as noncovalent organocatalysts to promote a highly selective aza-Michael reaction between primary alkyl amines and β-trifluoromethyl β-aryl nitroolefins. In contrast to classical conjugate-addition reactions, a strategy of HOMO-raising activation was used. Chiral trifluoromethylated amines were synthesized in high yield (up to 99 %) with excellent enantioselectivity (up to 98 % ee).

  5. US health journal editors' opinions and policies on research in race, ethnicity, and health.

    PubMed

    Bennett, T; Bhopal, R

    1998-07-01

    Health research on race and ethnicity has been criticized for lacking rigor in conceptualization, terminology, and analysis. Scientific journals' editorial processes help determine research quality. This survey assessed editors' awareness of current debates, attitudes toward recent recommendations, and involvement in developing editorial policies. Twenty-nine editors of health journals with impact factors of > or = 1 (based on citation ratings) were sent a questionnaire including four key problems identified in research literature and recommendations from federal agencies; 23 (79%) responded. Seven editors relevant policies. Two had read the federal directive on racial and ethnic classification; one was aware of its current review. Most perceived the four key problems as uncommon. The majority agreed with Public Health Service recommendations on race and ethnicity research, except for analyzing effects of racism. Approximately 20% had discussed issues with co-editors, editorial boards, or reviewers. About 40% saw further discussion as beneficial; four planned to draft guidelines. Editors' potential for helping resolve problems in race/ethnicity research is not being realized. Greater participation would be beneficial to public health research and practice.

  6. [The relevance of the International Committee of Medical Journal Editors (ICMJE) for medical publishing and research].

    PubMed

    Reyes, Humberto B

    2014-01-01

    The International Committee of Medical Journal Editors is a leading independent institution providing guidance for the report of biomedical research and health related topics in medical journals. Established in 1978, it is currently constituted by editors of fourteen general medical journals from different countries, plus one representative for the US National Library of Medicine and one representative for the World Association of Biomedical Journal Editors. Since 1978 the Committee provides a document, originally named "Uniform Requirements…", "to help authors, editors, and others involved in peer review and biomedical publishing create and distribute accurate, clear, unbiased medical journal articles". This document has been updated several times and the last version was released in August 2013, now renamed "Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals", available in www.icmje.org and citable as "ICMJE Recommendations". A vast proportion of medical journals, worldwide, have adopted these recommendations as rules. The ICMJE discusses and provides guidance on several relevant aspects including criteria on authorship, peer review, scientific misconduct, conflicts of interest, clinical trials registration, good editorial practices, the relations between editors and journal owners, the protection of individuals subject to medical research, the solvency of electronic publications, among others. The 2013 ICMJE Annual Meeting took place in Santiago, Chile, in November 4 and 5. The photograph shows attendants to the final session.

  7. US health journal editors' opinions and policies on research in race, ethnicity, and health.

    PubMed Central

    Bennett, T.; Bhopal, R.

    1998-01-01

    Health research on race and ethnicity has been criticized for lacking rigor in conceptualization, terminology, and analysis. Scientific journals' editorial processes help determine research quality. This survey assessed editors' awareness of current debates, attitudes toward recent recommendations, and involvement in developing editorial policies. Twenty-nine editors of health journals with impact factors of > or = 1 (based on citation ratings) were sent a questionnaire including four key problems identified in research literature and recommendations from federal agencies; 23 (79%) responded. Seven editors relevant policies. Two had read the federal directive on racial and ethnic classification; one was aware of its current review. Most perceived the four key problems as uncommon. The majority agreed with Public Health Service recommendations on race and ethnicity research, except for analyzing effects of racism. Approximately 20% had discussed issues with co-editors, editorial boards, or reviewers. About 40% saw further discussion as beneficial; four planned to draft guidelines. Editors' potential for helping resolve problems in race/ethnicity research is not being realized. Greater participation would be beneficial to public health research and practice. PMID:9685775

  8. STK Integrated Message Production List Editor (SIMPLE) for CEO Operations

    NASA Technical Reports Server (NTRS)

    Trenchard, Mike; Heydorn, James

    2014-01-01

    Late in fiscal year 2011, the Crew Earth Observations (CEO) team was tasked to upgrade and replace its mission planning and mission operations software systems, which were developed in the Space Shuttle era of the 1980s and 1990s. The impetuses for this change were the planned transition of all workstations to the Windows 7 64-bit operating system and the desire for more efficient and effective use of Satellite Tool Kit (STK) software required for reliable International Space Station (ISS) Earth location tracking. An additional requirement of this new system was the use of the same SQL database of CEO science sites from the SMMS, which was also being developed. STK Integrated Message Production List Editor (SIMPLE) is the essential, all-in-one tool now used by CEO staff to perform daily ISS mission planning to meet its requirement to acquire astronaut photography of specific sites on Earth. The sites are part of a managed, long-term database that has been defined and developed for scientific, educational, and public interest. SIMPLE's end product is a set of basic time and location data computed for an operator-selected set of targets that the ISS crew will be asked to photograph (photography is typically planned 12 to 36 hours out). The CEO operator uses SIMPLE to (a) specify a payload operations planning period; (b) acquire and validate the best available ephemeris data (vectors) for the ISS during the planning period; (c) ingest and display mission-specific site information from the CEO database; (d) identify and display potential current dynamic event targets as map features; (e) compute and display time and location information for each target; (f) screen and select targets based on known crew availability constraints, obliquity constraints, and real-time evaluated constraints to target visibility due to illumination (sun elevation) and atmospheric conditions (weather); and finally (g) incorporate basic, computed time and location information for each selected

  9. Michael K. Scullin: Psi Chi/APA Edwin B. Newman Graduate Research Award.

    PubMed

    2011-11-01

    Presents Michael K. Scullin as the 2011 winner of the American Psychological Association Psi Chi/APA Edwin B. Newman Graduate Research Award. "For an outstanding research paper that examines the relationship between prospective memory in executing a goal and various lapses of time from 20 minutes up to a 12- hour wake delay and a 12-hour sleep delay. The results suggest that consolidation processes active during sleep increase the probability of goal execution. The paper, titled 'Remembering to Execute a Goal: Sleep On It!' was published in Psychological Science in 2010 and was the basis for Michael K. Scullin's selection as the recipient of the 2011 Psi Chi/APA Edwin B. Newman Graduate Research Award. Mark A. McDaniel, PhD, served as faculty research advisor." (PsycINFO Database Record (c) 2011 APA, all rights reserved).

  10. Sir Michael Francis Addison Woodruff (1911-2001) FRS DSc MD MS FRCS.

    PubMed

    Leigh, Winston

    2011-02-01

    Michael Woodruff performed the first successful renal transplant in the UK and described the technique of joining the ureter of the transplant to the bladder. He contributed to all aspects of transplantation biology and was responsible for the design of the first purpose-built transplant unit in the world. As a Japanese prisoner of war at Changi in Singapore, Michael Woodruff studied the effects of malnutrition and devised a machine for extracting vitamins and trace elements from grass. After the war he demonstrated that the anterior chamber of the eye was an immunologically privileged site. He was the first person to describe 'adaptation'. He showed that antilymphocytic serum was effective as an immunosuppressive agent for homografts.

  11. Synthesis of dithiafulvene-quinone donor-acceptor systems: isolation of a Michael adduct.

    PubMed

    Lissau, Henriette; Jevric, Martyn; Madsen, Anders Østergaard; Nielsen, Mogens Brøndsted

    2015-06-01

    π-Conjugated donor-acceptor systems based on dithiafulvene (DTF) donor units and various acceptor units have attracted attention for their linear and nonlinear optical properties. The reaction between p-benzoquinone and a 1,3-dithiole phosphonium salt, deprotonated by lithium hexamethyldisilazide (LiHMDS), gave a product mixture from which the Michael adduct [systematic name: dimethyl 2-(3-hydroxy-6-oxocyclohexa-2,4-dien-1-ylidene)-2H-1,3-dithiole-4,5-dicarboxylate], C13H10O6S2, was isolated. It is likely that one of the unidentified products obtained previously by others from related reactions could be a similar Michael adduct.

  12. Accessing N-Stereogenicity through a Double Aza-Michael Reaction: Mechanistic Insights.

    PubMed

    Kohrt, Sonja; Santschi, Nico; Cvengroš, Ján

    2016-01-01

    Further development of the chemistry and applications of chiral compounds that possess configurationally stable stereogenic nitrogen atoms is hampered by the lack of efficient strategies to access such compounds in an enantiomerically pure form. Esters of propiolic acid and chiral alcohols were evaluated as cheap and readily available Michael acceptors in a diastereoselective synthesis of N-stereogenic compounds by means of a double aza-Michael conjugate addition. Diastereomeric ratios of up to 74:26 and high yields were achieved with (-)-menthyl propiolate as a substrate. Furthermore, a detailed mechanistic investigation was undertaken to shed some light on the course of this domino transformation. Kinetic studies revealed that the protic-solvent additive acts as a Brønsted acid and activates the ester toward the initial attack of the tetrahydrodiazocine partner. Conversely, acidic conditions proved unfavorable during the final cyclization step that provides the product.

  13. Highlighting High Performance: Michael E. Capuano Early Childhood Center; Somerville, Massachusetts

    SciTech Connect

    Not Available

    2006-03-01

    This brochure describes the key high-performance building features of the Michael E. Capuano Early Childhood Center. The brochure was paid for by the Massachusetts Technology Collaborative as part of their Green Schools Initiative. High-performance features described are daylighting and energy-efficient lighting, indoor air quality, solar and wind energy, building envelope, heating and cooling systems, water conservation, and acoustics. Energy cost savings are also discussed.

  14. Deracemizing organocatalyzed Michael addition reactions of 2-(arylthio)cyclobutanones with β-nitrostyrenes.

    PubMed

    Luridiana, Alberto; Frongia, Angelo; Aitken, David J; Guillot, Regis; Sarais, Giorgia; Secci, Francesco

    2016-04-01

    Organocatalyzed Michael addition reactions of 2-(arylthio)cyclobutanones with trans-β-nitrostyrenes have been carried out using a bifunctional thiourea-primary amine catalyst, providing diastereoisomerically and enantiomerically enriched 2-alkyl-2-(arylthio)cyclobutanones having two contiguous stereocenters of which one is a chiral quaternary center. The absolute configuration of these novel adducts was assigned by X-ray diffraction analysis and a transition-state model is proposed to explain the observed stereoselectivities.

  15. Thiourea catalyzed organocatalytic enantioselective Michael addition of diphenyl phosphite to nitroalkenes.

    PubMed

    Alcaine, Ana; Marqués-López, Eugenia; Merino, Pedro; Tejero, Tomás; Herrera, Raquel P

    2011-04-21

    Bifunctional thiourea catalyzes the enantioselective Michael addition reaction of diphenyl phosphite to nitroalkenes. This methodology provides a facile access to enantiomerically enriched β-nitrophosphonates, precursors for the preparation of synthetically and biologically useful β-aminophosphonic acids. DFT level of computational calculations invoke the attack of the diphenyl phosphite to the nitroolefin by the Re face, this give light to this scarcely explored process update in the literature. The computational calculations support the absolute configuration obtained in the final adducts.

  16. Stereodivergent Organocatalytic Intramolecular Michael Addition/Lactonization for the Asymmetric Synthesis of Substituted Dihydrobenzofurans and Tetrahydrofurans

    PubMed Central

    Belmessieri, Dorine; de la Houpliere, Alix; Calder, Ewen D D; Taylor, James E; Smith, Andrew D

    2014-01-01

    A stereodivergent asymmetric Lewis base catalyzed Michael addition/lactonization of enone acids into substituted dihydrobenzofuran and tetrahydrofuran derivatives is reported. Commercially available (S)-(−)-tetramisole hydrochloride gives products with high syn diastereoselectivity in excellent enantioselectivity (up to 99:1 d.r.syn/anti, 99 % eesyn), whereas using a cinchona alkaloid derived catalyst gives the corresponding anti-diastereoisomers as the major product (up to 10:90 d.r.syn/anti, 99 % eeanti). PMID:24989672

  17. STS-113 Mission Specialist Michael Lopez-Alegria looks over the P1 Truss

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-113 Mission Specialist Michael Lopez-Alegria looks over the P1 Integrated Truss Structure, the primary payload for the mission. The P1 truss will be attached to the central truss segment, S0 Truss, during spacewalks. The payload also includes the Crew and Equipment Translation Aid (CETA) Cart B that can be used by spacewalkers to move along the truss with equipment. STS-113 is scheduled to launch Oct. 6, 2002.

  18. STS-69 MS Michael L. Gernhardt greets his mother at SLF

    NASA Technical Reports Server (NTRS)

    1995-01-01

    STS-69 Mission Specialist Michael L. Gernhardt (right) gets a chance to say hi to his mother, Suzanne Winters, and her husband Doug, after the STS-69 flight crew arrived at KSC's Shuttle Landing Facility. The five astronauts assigned to the mission are looking forward to a liftoff aboard the Space Shuttle Endeavour during a two and a half hour window opening at 11:09 a.m. EDT, Sept. 7.

  19. Group 12, 1987 ASCAN C. Michael Foale sits at the pilots station in JSC's FFT

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Group 12, 1987 Astronaut Candidate (ASCAN) C. Michael Foale sits at the forward flight deck pilots station controls in JSC's Full Fuselage Trainer (FFT). The FFT is used to familiarize the astronauts with the hardware in the cockpit of the Space Shuttle orbiters. It is one of the mockup training devices located in the Mockup and Integration Laboratory (MAIL) Bldg 9NE. Foale is one of 15 ASCANs recently selected by NASA.

  20. Michael's Marathon: My Experience of Overcoming Illiteracy as an Adult. Literacy Lessons.

    ERIC Educational Resources Information Center

    Marquet, Michael

    Michael Marquet of New Zealand left school 10 years ago, not able to read or write and with a serious speech problem. He had spent 9 years in a special class and had learned very little. He had completed 2 years of high school and left at the end of the fourth form, at the age of 15 and with no qualifications. However, he had participated in a…

  1. A celebration of mechanics: from nano to macro. The J. Michael T. Thompson Festschrift issue.

    PubMed

    Elishakoff, Isaac

    2013-06-28

    This Theme Issue is dedicated to the topic 'Mechanics: from nano to macro' and marks the 75th birthday of Dr J. Michael T. Thompson, Fellow of the Royal Society, whose current affiliations are as follows: (i) Honorary Fellow, Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge; (ii) Emeritus Professor of Nonlinear Dynamics, Department of Civil, Environmental and Geomatic Engineering, University College London; and (iii) Professor of Theoretical and Applied Dynamics (Distinguished Sixth Century Chair, part-time), University of Aberdeen. He also serves as Chairman of the Board of Directors at ES-Consult (consulting engineers) in Copenhagen, Denmark. The pertinent question that arises from the very start is: should we first salute Michael and then describe the Theme Issue, or vice versa? Indeed, according to Blaise Pascal (1623-1662), the last thing one discovers in composing a work is what to put first. I would like to take the liberty of deviating from the tradition of the Philosophical Transactions and start with the tribute to Michael; after all he is the prime cause of this Theme Issue.

  2. Role of editors and journals in detecting and preventing scientific misconduct: strengths, weaknesses, opportunities, and threats.

    PubMed

    Marusic, Ana; Katavic, Vedran; Marusic, Matko

    2007-09-01

    Scientific journals have a central place in protecting research integrity because published articles are the most visible documentation of research. We used SWOT analysis to audit (S)trengths and (W)eaknesses as internal and (O)pportunities and (T)hreats as external factors affecting journals' responsibility in addressing research integrity issues. Strengths include editorial independence, authority and expertise, power to formulate editorial policies, and responsibility for the integrity of published records. Weaknesses stem from having no mandate for legal action, reluctance to get involved, and lack of training. Opportunities for editors are new technologies for detecting misconduct, policies by editorial organization or national institutions, and greater transparency of published research. Editors face threats from the lack of legal regulation and culture of research integrity in academic communities, lack of support from stakeholders in scientific publishing, and different pressures. Journal editors cannot be the policing force of the scientific community but they should actively ensure the integrity of the scientific record.

  3. Transferable Output ASCII Data (TOAD) editor version 1.0 user's guide

    NASA Technical Reports Server (NTRS)

    Bingel, Bradford D.; Shea, Anne L.; Hofler, Alicia S.

    1991-01-01

    The Transferable Output ASCII Data (TOAD) editor is an interactive software tool for manipulating the contents of TOAD files. The TOAD editor is specifically designed to work with tabular data. Selected subsets of data may be displayed to the user's screen, sorted, exchanged, duplicated, removed, replaced, inserted, or transferred to and from external files. It also offers a number of useful features including on-line help, macros, a command history, an 'undo' option, variables, and a full compliment of mathematical functions and conversion factors. Written in ANSI FORTRAN 77 and completely self-contained, the TOAD editor is very portable and has already been installed on SUN, SGI/IRIS, and CONVEX hosts.

  4. Surface Modified Particles By Multi-Step Michael-Type Addition And Process For The Preparation Thereof

    DOEpatents

    Cook, Ronald Lee; Elliott, Brian John; Luebben, Silvia DeVito; Myers, Andrew William; Smith, Bryan Matthew

    2005-05-03

    A new class of surface modified particles and a multi-step Michael-type addition surface modification process for the preparation of the same is provided. The multi-step Michael-type addition surface modification process involves two or more reactions to compatibilize particles with various host systems and/or to provide the particles with particular chemical reactivities. The initial step comprises the attachment of a small organic compound to the surface of the inorganic particle. The subsequent steps attach additional compounds to the previously attached organic compounds through reactive organic linking groups. Specifically, these reactive groups are activated carbon—carbon pi bonds and carbon and non-carbon nucleophiles that react via Michael or Michael-type additions.

  5. Rh(III)-Catalyzed C-H Bond Addition/Amine-Mediated Cyclization of Bis-Michael Acceptors.

    PubMed

    Potter, Tyler J; Ellman, Jonathan A

    2016-08-01

    A Rh(III)-catalyzed C-H bond addition/primary amine-promoted cyclization of bis-Michael acceptors is reported. The C-H bond addition step occurs with high chemoselectivity, and the subsequent intramolecular Michael addition, mediated by a primary amine catalyst, sets three contiguous stereocenters with high diastereoselectivity. A broad range of directing groups and both aromatic and alkenyl C-H bonds were shown to be effective in this transformation, affording functionalized piperidines, tetrahydropyrans, and cyclohexanes.

  6. An interactive editor for definition of touch-sensitive zones for a graphic display

    NASA Technical Reports Server (NTRS)

    Monroe, Burt L., III; Jones, Denise R.

    1987-01-01

    In the continuing effort to develop more efficient man-machine communications methods, touch displays have shown potential as straightforward input systems. The development of software necessary to handle such systems, however, can become tedious. In order to reduce the need for redundant programming, a touch editor has been developed which allows a programmer to interactively define touch-sensitive areas for a graphic display. The information produced during the editing process is written to a data file, which can be accessed easily when needed by an application program. This paper outlines the structure, logic, and use of the editor, as well as the hardware with which it is presently compatible.

  7. Improving the quality of papers submitted to dental journals: Transcription of session for editors, associate editors, publishers and others with an interest in scientific publishing held at IADR meeting in Cape Town on Wednesday, 25 June 2014.

    PubMed

    Eaton, Kenneth A; Giannobile, William V; Sourgen, Deborah L; Balaji, S M; Honkala, Eino; Lynch, Christopher D

    2015-08-01

    This satellite symposium was the fourth in a series for editors, publishers, reviewers and all those with an interest in scientific publishing. It was held on Wednesday 25th June 2014 at the IADR International meeting in Cape Town, South Africa. The symposium attracted more than 180 attendees. This symposium placed an emphasis on how the quality of papers submitted to dental journals could be improved. The panel included representation from editors, researchers and publishers from North America, India and the Gulf States. The symposium identified a number of challenges for editors and publishers, including the poor quality of many papers submitted to dental and other scientific journals, plagiarism, attempted duplicate publication and sometimes fraudulent results. Where possible speakers are identified by name. A subsequent symposium was held during the IADR meeting in Boston on March 11th 2015. Involvement open to editors, associate editors, publishers and others with an interest in scientific publishing.

  8. Improving the quality of papers submitted to dental journals: Transcription of session for editors, associate editors, publishers and others with an interest in scientific publishing held at IADR meeting in Cape Town on Wednesday, 25 June 2014.

    PubMed

    Eaton, Kenneth A; Giannobile, William V; Sourgen, Deborah L; Balaji, S M; Honkala, Eino; Lynch, Christopher D

    2015-08-01

    This satellite symposium was the fourth in a series for editors, publishers, reviewers and all those with an interest in scientific publishing. It was held on Wednesday 25th June 2014 at the IADR International meeting in Cape Town, South Africa. The symposium attracted more than 180 attendees. This symposium placed an emphasis on how the quality of papers submitted to dental journals could be improved. The panel included representation from editors, researchers and publishers from North America, India and the Gulf States. The symposium identified a number of challenges for editors and publishers, including the poor quality of many papers submitted to dental and other scientific journals, plagiarism, attempted duplicate publication and sometimes fraudulent results. Where possible speakers are identified by name. A subsequent symposium was held during the IADR meeting in Boston on March 11th 2015. Involvement open to editors, associate editors, publishers and others with an interest in scientific publishing. PMID:25748020

  9. EDITORIAL: Editorial from the new Editor-in-Chief for 2014 Editorial from the new Editor-in-Chief for 2014

    NASA Astrophysics Data System (ADS)

    Graham, W. G.

    2014-02-01

    I am honoured to take on the leadership of Plasma Sources Science and Technology (PSST) as the successor to Professor Mark J Kushner, with whom I have had the pleasure to work on the journal for many years. Under Mark's insightful and energetic leadership over the last six years, PSST has cemented its position as the journal of choice within its subject area and is now one of the most successful journals in the field. In this first issue of 2014, I would like to reflect on some of the events and achievements of 2013. At the start of the year the PSST Editorial Board, recognizing the vital importance of atomic, molecular and optical (AMO) data to low-temperature plasma physics, agreed that PSST would accept papers reporting such new data, generated through both experiment and theory. Jonathan Tennyson joined the Editorial Board to represent this area. In March Anne Bourdon joined the Associate Editor team and has since then played a key part in the journal's review process alongside our other Editors. During the autumn, PSST moved to a new editorial management system. In December Deborah O'Connell was awarded the 2013 Hershkowitz Early Career Award and Review and joins the Editorial Board as of 2014. I would also like to thank Miles Turner for his work in leading the drafting of a guide on the details necessary in the reporting of the results of computer simulations; the main conclusions of this report have been incorporated into the journal policy. Overall 2013 has been another successful year for PSST; paper submissions were up by 8% on the previous year and there was the highest ever number of downloads of PSST papers in one year. Another noteworthy feature of 2013 was the continuing improvement in publication times while maintaining our high standards for acceptance and providing expert feedback coupled with encouragement particularly to younger researchers and groups. Largely as a result of the hard work of our referees and Associate Editors, the average time

  10. What Editors and Journalism Educators Expect from Journalism Education; An ANPA News Research Center Survey. News Research Bulletin No. 12.

    ERIC Educational Resources Information Center

    Hulteng, John L.

    The purpose of this survey was to assemble data about the expectations of editors and journalism educators as to journalism education, with the objective of providing a basis for an informed dialogue about ways to advance and support education for journalism. Some of the findings were: editors much less than educators perceived newly-hired…

  11. A Study of the Coorientation of High School Principals, Journalism Teachers, and Local Newspaper Editors in Selected Iowa Communities.

    ERIC Educational Resources Information Center

    Peterson, Jane W.

    A study investigated the extent to which high school journalism teachers, principals, and local newspaper editors in selected Iowa communities have a common understanding of each other and the issues of high school journalism. A questionnaire sent to 187 newspaper editors, high school principals, and journalism teachers was returned by 118…

  12. Advancing the Profession through Journals: The Editor-Author-Profession Partnership [in HRD].

    ERIC Educational Resources Information Center

    1995

    These three papers are from a symposium on professional journals that was facilitated by Wim J. Nijhoff at the 1995 Academy of Human Resource Development (HRD) conference. "Advancing the Profession through Journals: The Editor-Author-Profession Partnership" (Gary N. McLean) describes the purpose and operation of the "Human Resource Development…

  13. Editorial: Conflict of interest policy for Editors of The American Journal of Clinical Nutrition

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Integrity in the publication process requires impartiality at all levels of review. The American Journal of Clinical Nutrition (AJCN) adheres to the policy of the International Committee of Medical Journal Editors (ICMJE), Uniform Requirements for Manuscripts Submitted to Biomedical Journals: Writin...

  14. The Newspaper Editor As Graphic Strategist. ANPA News Research Report No. 27.

    ERIC Educational Resources Information Center

    Garcia, Mario R.

    This report discusses the graphic strategies available to editors for positioning the day's news. The purposes of the report are: (1) to introduce those in charge of designing the newspaper page to the structural approach to design (the structural approach is defined as incorporating horizontal and vertical structures in the available spaces,…

  15. Professional Wisdom and Writing for Publication: Qualitative Interviews with Editors and Authors in Early Childhood Education

    ERIC Educational Resources Information Center

    Jalongo, Mary Renck

    2013-01-01

    College and university faculty members specializing in early childhood education face some unique challenges in scholarly writing. The purpose of this research was to use open-ended interviews as a way to gather the collective wisdom of a group of key informants about academic writing and publishing in the field. Twenty-two editors and/or authors,…

  16. An International Call for Democratizing the Academic Journal Culture from a Community of Editors

    ERIC Educational Resources Information Center

    Mullen, Carol A.; Pryor, Caroline R.; Browne-Ferrigno, Tricia; Harris, Sandra L.

    2013-01-01

    In our reflective essay from our multiple perspectives as journal editors, peer reviewers, and published authors, we present ideas about editorial support, democracy, and innovation in the publishing process. As four tenured professors who work in universities in the states of Illinois, Virginia, Texas, and Kentucky, we are a community of editors…

  17. Light chain editors of anti-DNA receptors in human B cells.

    PubMed

    Kalinina, Olga; Wang, Yue; Sia, Kevin; Radic, Marko; Cazenave, Pierre-André; Weigert, Martin

    2014-02-10

    Receptor editing is a mechanism of self-tolerance used in newly generated B cells. The expressed heavy (H) or light (L) chain of an autoreactive receptor is replaced by upstream V genes which eliminate or modify autoreactivity. Editing of anti-DNA receptors has been characterized in anti-DNA transgenic mouse models including 3H9, 3H9/56R, and their revertant 3H9GL. Certain L chains, termed editors, rescue anti-DNA B cells by neutralizing or modifying DNA binding of the H chain. This editing mechanism acts on the natural H chain repertoire; endogenous H chains with anti-DNA features are expressed primarily in combination with editor L chains. We ask whether a similar set of L chains exists in the human repertoire, and if so, do they edit H chains with anti-DNA signatures? We compared the protein sequences of mouse editors to all human L chains and found several human L chains similar to mouse editors. These L chains diminish or veto anti-DNA binding when expressed with anti-DNA H chains. The human H chains expressed with these L chains also have relatively high arginine (Arg) content in the H chain complementarity determining region (H3), suggesting that receptor editing plays a role in establishing tolerance to DNA in humans.

  18. Persnickety editor, Founding Father, Mentor and Friend: The Legacy of Fred Mumpton

    NASA Technical Reports Server (NTRS)

    Ming, Douglas W.

    2006-01-01

    This paper is a tribute to Dr Fred Munpton, the founder of the International Committee on Natural Zeolites (ICNZ), by one of his students, who later succeed him as president of the ICNZ. The tribute reflects on Dr. Mumpton's skills as an editor and his zeal for the study of natural zeolites.

  19. Using letters to the editor to try to bring science to the public

    NASA Astrophysics Data System (ADS)

    Aubrecht, Gordon

    2009-10-01

    The local paper here, the Delaware Gazette, publishes many letters from global warming skeptics and people ignorant of energy policy. I explain how I attempt to bring some sense to the situation through reply letters to the editor. Scientists need to express scientific views in public as our duty to fellow citizens.

  20. Learning the Attachment Theory with the CM-ED Concept Map Editor

    ERIC Educational Resources Information Center

    Rueda, U.; Arruarte, A.; Elorriaga, J. A.; Herran, E.

    2009-01-01

    This paper presents a study carried out at the University of the Basque Country UPV/EHU with the aim of evaluating the CM-ED (concept map editor) with social education students. Concept mapping is a widely accepted technique that promotes meaningful learning. Graphically representing concepts of the learning domain and relationships between them…

  1. Guidelines for Reviewers and the Editor at the Nuclear Safety Information Center.

    ERIC Educational Resources Information Center

    Whetsel, H. B.

    The main purpose of this report is to help novice reviewers accelerate their apprenticeship at the Nuclear Safety Information Center, a computerized information service sponsored by the U.S. Atomic Energy Commission. Guidelines for reviewers are presented in Part 1; Part 2 contains guidelines for the novice editor. The goal of the reviewers and…

  2. University-government relationships in the training of technical writers-editors

    NASA Technical Reports Server (NTRS)

    Stohrer, Freda F.; Pinelli, Thomas E.

    1979-01-01

    Traditional and nontraditional methods of training technical writers-editors are reviewed. Combining work experience with classroom instruction in the form of cooperative education provides a method of strengthening the Federal career service in professional occupations. The NASA Langley experience that successfully introduced students to the special demands of technical writing and editing is described.

  3. Improving the Yield of Rural Education Research: An Editor's Swan Song

    ERIC Educational Resources Information Center

    Coladarci, Theodore

    2007-01-01

    In my 15th and final year as JRRE editor, I identify methodological and substantive shortcomings in the rural education research literature and, in turn, suggest strategies for improvement. I structure my observations around the following considerations: describing the rural context of research, making the rural argument, framing the research…

  4. Evolution of Novice Programming Environments: The Structure Editors of Carnegie Mellon University.

    ERIC Educational Resources Information Center

    Miller, Philip; And Others

    1994-01-01

    Describes three projects at Carnegie Mellon University (Pennsylvania) that developed novice programming environments based on structure editors: GNOME, MacGNOME and ACSE (Advanced Computing for Science Education). Tracks the evolution of the programming environments and courses, documenting important lessons and discoveries about novice…

  5. SPADE: A Grammar Based Editor for Planning and Debugging Programs. AI Memo 386.

    ERIC Educational Resources Information Center

    Miller, Mark L.; Goldstein, Ira P.

    The Structured Planning and Debugging Editor (SPADE) is a new kind of interactive programming environment in which computer programs are generated by explicitly articulating planning decisions. The design of SPADE is based upon the development of a grammar of plans from a taxonomy of basic planning techniques. The utility of this approach to…

  6. Guidelines, editors, pharma and the biological paradigm shift.

    PubMed

    Singh, Ajai R; Singh, Shakuntala A

    2007-01-01

    relatively recent survey of 2002, it was found that about 60% of 192 authors of clinical practice guidelines reported they had financial connections with the companies whose drugs were under consideration. There is a strong case for making CPGs based not just on effectivity but cost effectivity. The various ramifications of this need to be spelt out. Work of bodies like the Appraisal of Guidelines Research and Evaluation (AGREE) Collaboration and Guidelines Advisory Committee (GAC) are also worth a close look.Even the actions of Foundations that work for disease amelioration have come under scrutiny. The process of setting up 'Best Practices' Guidelines for interactions between the pharmaceutical industry and clinicians has already begun and can have important consequences for patient care. Similarly, Good Publication Practice (GPP) for pharmaceutical companies have also been set up aimed at improving the behaviour of drug companies while reporting drug trialsThe rapidly increasing trend toward influence and control by industry has become a concern for many. It is of such importance that the Association of American Medical Colleges has issued two relatively new documents - one, in 2001, on how to deal with individual conflicts of interest; and the other, in 2002, on how to deal with institutional conflicts of interest in the conduct of clinical research. Academic Medical Centers (AMCs), as also medical education and research institutions at other places, have to adopt means that minimize their conflicts of interest.Both medical associations and research journal editors are getting concerned with individual and institutional conflicts of interest in the conduct of clinical research and documents are now available which address these issues. The 2001 ICMJE revision calls for full disclosure of the sponsor's role in research, as well as assurance that the investigators are independent of the sponsor, are fully accountable for the design and conduct of the trial, have

  7. Guidelines, editors, pharma and the biological paradigm shift.

    PubMed

    Singh, Ajai R; Singh, Shakuntala A

    2007-01-01

    relatively recent survey of 2002, it was found that about 60% of 192 authors of clinical practice guidelines reported they had financial connections with the companies whose drugs were under consideration. There is a strong case for making CPGs based not just on effectivity but cost effectivity. The various ramifications of this need to be spelt out. Work of bodies like the Appraisal of Guidelines Research and Evaluation (AGREE) Collaboration and Guidelines Advisory Committee (GAC) are also worth a close look.Even the actions of Foundations that work for disease amelioration have come under scrutiny. The process of setting up 'Best Practices' Guidelines for interactions between the pharmaceutical industry and clinicians has already begun and can have important consequences for patient care. Similarly, Good Publication Practice (GPP) for pharmaceutical companies have also been set up aimed at improving the behaviour of drug companies while reporting drug trialsThe rapidly increasing trend toward influence and control by industry has become a concern for many. It is of such importance that the Association of American Medical Colleges has issued two relatively new documents - one, in 2001, on how to deal with individual conflicts of interest; and the other, in 2002, on how to deal with institutional conflicts of interest in the conduct of clinical research. Academic Medical Centers (AMCs), as also medical education and research institutions at other places, have to adopt means that minimize their conflicts of interest.Both medical associations and research journal editors are getting concerned with individual and institutional conflicts of interest in the conduct of clinical research and documents are now available which address these issues. The 2001 ICMJE revision calls for full disclosure of the sponsor's role in research, as well as assurance that the investigators are independent of the sponsor, are fully accountable for the design and conduct of the trial, have

  8. Diagnosis: Michael Moore--media paint filmmaker to be health care system's main problem.

    PubMed

    Kao, Caroline

    2008-01-01

    The media reporting on Sicko, Michael Moore's documentary about the failures of the U.S. health care system, provides an example of how corporate media continue to twist and restrict the much-needed debate on health care reform. Aside from an occasional concession that having 46 million uninsured Americans is indeed problematic, the media's hype-filled conversation on health care avoids the issues and echoes old myths about the dangers of "government-run" and "socialized" health care. But in the face of the media demonization, universal health care is remarkably popular among the public. PMID:18341130

  9. Michael E. Lamb: Award for Distinguished Senior Career Contributions to Psychology in the Public Interest.

    PubMed

    2015-11-01

    The APA Awards for Distinguished Contributions to Psychology in the Public Interest recognize persons who have advanced psychology as a science and/or profession by a single extraordinary achievement or a lifetime of outstanding contributions in the public interest. The 2015 co-recipient of the Award for Distinguished Senior Career Contributions to Psychology in the Public Interest is Michael E. Lamb. Lamb was selected because his "work profoundly shaped the fields of developmental psychology, social welfare, child and family policy, and law." Lamb's award citation, biography, and a selected bibliography are presented here.

  10. A Promiscuous De Novo Retro-Aldolase Catalyzes Asymmetric Michael Additions via Schiff Base Intermediates.

    PubMed

    Garrabou, Xavier; Beck, Tobias; Hilvert, Donald

    2015-05-01

    Recent advances in computational design have enabled the development of primitive enzymes for a range of mechanistically distinct reactions. Here we show that the rudimentary active sites of these catalysts can give rise to useful chemical promiscuity. Specifically, RA95.5-8, designed and evolved as a retro-aldolase, also promotes asymmetric Michael additions of carbanions to unsaturated ketones with high rates and selectivities. The reactions proceed by amine catalysis, as indicated by mutagenesis and X-ray data. The inherent flexibility and tunability of this catalyst should make it a versatile platform for further optimization and/or mechanistic diversification by directed evolution. PMID:25777153

  11. A summary of seven- and eight-membered ring sultam syntheses via three Michael addition reactions.

    PubMed

    Niu, Ben; Xie, Ping; Wang, Min; Wang, Yanjie; Zhao, Wannian; Pittman, Charles U; Zhou, Aihua

    2015-08-01

    A series of seven- and eight-membered ring -N,O-, -N,N-, and -N,S-sultams were effectively synthesized via tandem reactions involving oxa-, aza-, and thia-Michael addition to vinyl sulfonamides. These reactions are summarized here since they enrich current synthetic methodologies for sultams and provide a good example of sultam diversity-oriented synthesis. All reactions proceeded under relatively mild and environmentally friendly conditions, and all these reactions are quite suitable for the rapid preparation of sultam compound libraries, which are valuable for biological activity explorations.

  12. Conversion of Substrate Analogs Suggests a Michael Cyclization in Iridoid Biosynthesis

    PubMed Central

    Lindner, Stephanie; Geu-Flores, Fernando; Bräse, Stefan; Sherden, Nathaniel H.; O’Connor, Sarah E.

    2014-01-01

    Summary The core structure of the iridoid monoterpenes is formed by a unique cyclization reaction. The enzyme that catalyzes this reaction, iridoid synthase, is mechanistically distinct from other terpene cyclases. Here we describe the synthesis of two substrate analogs to probe the mechanism of iridoid synthase. Enzymatic assay of these substrate analogs along with clues from the product profile of the native substrate strongly suggest that iridoid synthase utilizes a Michael reaction to achieve cyclization. This improved mechanistic understanding will facilitate the exploitation of the potential of iridoid synthase to synthesize new cyclic compounds from nonnatural substrates. PMID:25444551

  13. Supported bifunctional thioureas as recoverable and reusable catalysts for enantioselective nitro-Michael reactions

    PubMed Central

    Ceballos, Miriam; Maestro, Alicia; Sanz, Isabel

    2016-01-01

    Summary The catalytic activity of different supported bifunctional thioureas on sulfonylpolystyrene resins has been studied in the nitro-Michael addition of different nucleophiles to trans-β-nitrostyrene derivatives. The activity of the catalysts depends on the length of the tether linking the chiral thiourea to the polymer. The best results were obtained with the thiourea derived from (L)-valine and 1,6-hexanediamine. The catalysts can be used in only 2 mol % loading, and reused for at least four cycles in neat conditions. The ball milling promoted additions also worked very well. PMID:27340453

  14. Construction of highly functionalized diazoacetoacetates via catalytic Mukaiyama-Michael reactions.

    PubMed

    Liu, Yu; Zhang, Yu; Jee, Noel; Doyle, Michael P

    2008-04-17

    Functionalized diazo acetoacetates are prepared by an efficient Mukaiyama-Michael reaction between methyl 3-(trialkylsilanoxy)-2-diazo-3-butenoate and alpha,beta-unsaturated enones. Vinyl ether and ketone derivatives are both accessible in good to excellent yield through this methodology. The mild Lewis acid zinc(II) triflate is the optimal catalyst, and its loading can be as low as 0.1 mol %. In addition, zinc triflate was also found to be a superior catalyst for the related Mukaiyama-aldol reaction.

  15. Densely Substituted L-Proline Esters as Catalysts for Asymmetric Michael Additions of Ketones to Nitroalkenes.

    PubMed

    Ruiz-Olalla, Andrea; Retamosa, María de Gracia; Cossío, Fernando P

    2015-06-01

    Homochiral methyl 4-aminopyrrolidine-2-carboxylates are readily obtained by means of asymmetric (3 + 2) cycloadditions between azomethine ylides and nitroalkenes, followed by catalytic hydrogenation of the intermediate 4-nitro cycloadducts. These 4-aminopyrrolidine-2-carboxylate esters belong to the L-series of natural amino acids and catalyze asymmetric Michael additions of ketones to nitroalkenes. However, the enantioselectivity observed with these novel unnatural organocatalysts is opposite to that obtained with L-proline. Since both 4-nitro and 4-amino L-proline esters are efficient organocatalysts of aldol reactions, these results permit to modulate asymmetric quimioselective aldol and conjugate addition reactions.

  16. Asymmetric anti-selective Michael reaction of imidazole-modified ketones with trans-β-nitroalkenes.

    PubMed

    Yang, Dongxu; Wang, Linqing; Li, Dan; Han, Fengxia; Zhao, Depeng; Wang, Rui

    2015-01-19

    The successful application of imidazole-modified ketones in asymmetric anti-selective Michael reactions with trans-β-nitroalkenes is presented by employing a newly developed 3-bromothiophene-modified chiral diamine ligand. The corresponding conjugate adduct was submitted to further transformations with Grignard reagents to solve the problem of α-site selectivity of simple linear ketones. Additionally, the syn-selective product was obtained by treating the anti-selective adduct with a simple base. In this way, the site-specific products for both diastereomers in the asymmetric conjugate addition of simple ketones to nitroalkenes can be obtained. PMID:25446668

  17. Squaramide-Catalyzed Enantioselective Michael Addition of Masked Acyl Cyanides to Substituted Enones

    PubMed Central

    2013-01-01

    Masked acyl cyanide (MAC) reagents are shown to be effective umpolung synthons for enantioselective Michael addition to substituted enones. The reactions are catalyzed by chiral squaramides and afford adducts in high yields (90–99%) and with excellent enantioselectivities (85–98%). The addition products are unmasked to produce dicyanohydrins that, upon treatment with a variety of nucleophiles, provide γ-keto acids, esters, and amides. The use of this umpolung synthon has enabled, in enantiomerically enriched form, the first total synthesis of the prenylated phenol (+)-fornicin C. PMID:24090310

  18. Michael E. Barnes: Award for Distinguished Professional Contributions to Institutional Practice.

    PubMed

    2012-11-01

    Presents a short biography on the winner of the American Psychological Association's Award for Distinguished Professional Contributions to Institutional Practice. The 2012 winner is Michael E. Barnes for his pioneering leadership, dedication, and distinguished contributions to juvenile justice. As chief psychologist of the Superior Court of the District of Columbia's Child Guidance Clinic, Barnes and his staff have provided exceptional psychological service to thousands of adjudicated youths, developed an APA-accredited internship program, and supervised the development of a juvenile mental health court that diverts mentally ill court-involved youth from delinquency proceedings and into treatment.

  19. STS-113 Mission Specialist Michael Lopez-Alegria suits up for launch

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - STS-113 Mission Specialist Michael Lopez-Alegria suits up for launch. He will be making his third Shuttle flight. The primary mission for the crew is bringing the Expedition 6 crew to the Station and returning the Expedition 5 crew to Earth. The major objective of the mission is delivery of the Port 1 (P1) Integrated Truss Assembly, which will be attached to the port side of the S0 truss. Three spacewalks are planned to install and activate the truss and its associated equipment. Launch of Space Shuttle Endeavour on mission STS-113 is scheduled for 8:15 p.m. EST.

  20. STS-107 Payload Commander Michael Anderson during TCDT M113 training activities

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- -- STS-107 Payload Commander Michael Anderson takes a break during training on the operation of an M113 armored personnel carrier during Terminal Countdown Demonstration Test activities, a standard part of launch preparations. STS-107 is a mission devoted to research and will include more than 80 experiments that will study Earth and space science, advanced technology development, and astronaut health and safety. Launch is planned for Jan. 16, 2003, between 10 a.m. and 2 p.m. EST aboard Space Shuttle Columbia.

  1. STS-84 M.S. Michael Foale on M-113 carrier at TCDT

    NASA Technical Reports Server (NTRS)

    1997-01-01

    STS-84 Mission Specialist C. Michael Foale rides in an M-113 armored personnel carrier as part of the Terminal Countdown Demonstration Test (TCDT) activities. STS-84 aboard the Space Shuttle Atlantis will be the sixth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Foale will transfer to the space station and become a member of the Mir 23 crew, replacing U.S. astronaut Jerry M. Linenger, who will return to Earth aboard Atlantis. Foale will live and work on Mir until mid-September when his replacement is expected to arrive on the STS-86 mission. STS-84 is targeted for a May 15 liftoff.

  2. STS-89 Mission Specialist Michael Anderson is assisted with his flight suit in the white room

    NASA Technical Reports Server (NTRS)

    1998-01-01

    STS-89 Mission Specialist Michael Anderson is assisted with his ascent and re-entry flight suit in the white room at Launch Pad 39A before entering Space Shuttle Endeavour for launch. The STS- 89 mission will be the eighth docking of the Space Shuttle with the Russian Space Station Mir. After docking, Mission Specialist Andrew Thomas, Ph.D., will transfer to the space station, succeeding David Wolf, M.D., who will return to Earth aboard Endeavour. Dr. Thomas will live and work on Mir until June. STS- 89 is scheduled for a Jan. 22 liftoff at 9:48 p.m.

  3. STS-113 Mission Specialist Michael Lopez-Alegria suits up before launch

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- STS-113 Mission Specialist Michael Lopez-Alegria suits up before launch. This will be his third Shuttle flight. The primary mission is bringing the Expedition 6 crew to the Station and returning the Expedition 5 crew to Earth. The major objective of the mission is delivery of the Port 1 (P1) Integrated Truss Assembly, which will be attached to the port side of the S0 truss. Three spacewalks are planned to install and activate the truss and its associated equipment. Launch of Space Shuttle Endeavour on mission STS-113 is scheduled for Nov. 11 at 12:58 a.m. EST.

  4. Michael Servetus (1511-1553): physician and heretic who described the pulmonary circulation.

    PubMed

    Bosmia, Anand; Watanabe, Koichi; Shoja, Mohammadali M; Loukas, Marios; Tubbs, R Shane

    2013-07-31

    The purpose of this paper is to provide an overview of the life of the physician and theologian Michael Servetus and to discuss his analysis of the pulmonary circulation. Writers have praised Servetus for his commitment to educating his colleagues about what he heralded as the truth, and criticized him for his perceived arrogance. Servetus made contributions to the fields of geography, astrology, theology, and medicine. This paper refers to the translation of a portion of Servetus' book Christianismi Restitutio by Charles D. O'Malley. PMID:22748500

  5. Cinchona Alkaloid Catalyzed Sulfa-Michael Addition Reactions Leading to Enantiopure β-Functionalized Cysteines.

    PubMed

    Breman, Arjen C; Telderman, Suze E M; van Santen, Roy P M; Scott, Jamie I; van Maarseveen, Jan H; Ingemann, Steen; Hiemstra, Henk

    2015-11-01

    Sulfa-Michael additions to α,β-unsaturated N-acylated oxazolidin-2-ones and related α,β-unsaturated α-amino acid derivatives have been enantioselectively catalyzed by Cinchona alkaloids functionalized with a hydrogen bond donating group at the C6' position. The series of Cinchona alkaloids includes known C6' (thio)urea and sulfonamide derivatives and several novel species with a benzimidazole, squaramide or a benzamide group at the C6' position. The sulfonamides were especially suited as bifunctional organocatalysts as they gave the products in very good diastereoselectivity and high enantioselectivity. In particular, the C6' sulfonamides catalyzed the reaction with the α,β-unsaturated α-amino acid derivatives to afford the products in a diastereomeric ratio as good as 93:7, with the major isomer being formed in an ee of up to 99%. The products of the organocatalytic sulfa-Michael addition to α,β-unsaturated α-amino acid derivatives were subsequently converted in high yields to enantiopure β-functionalized cysteines suitable for native chemical ligation.

  6. Sustained release formulation of erythropoietin using hyaluronic acid hydrogels crosslinked by Michael addition.

    PubMed

    Hahn, Sei Kwang; Oh, Eun Ju; Miyamoto, Hajime; Shimobouji, Tsuyoshi

    2006-09-28

    A novel sustained release formulation of erythropoietin (EPO) was successfully developed using hyaluronic acid (HA) hydrogels crosslinked by Michael addition. Adipic acid dihydrazide grafted HA (HA-ADH) was prepared and then modified into methacrylated HA (HA-MA). (1)H NMR analysis showed that the degrees of HA-ADH and HA-MA modification were 69 and 29 mol%, respectively. Using the specific crosslinkers of dithiothreitol (DTT) and peptide linker, EPO was loaded during HA-MA hydrogel preparation by Michael addition chemistry between thiol and methacrylate groups. The amount of EPO recovered from both hydrogels after degradation with hyaluronidase SD (HAse SD) was about 90%. The crosslinking reaction with peptide linker (GCYKNRDCG) was faster than that with DTT. The gelation time was about 30 min for peptide linker and 180 min for DTT. In vitro release test of EPO from HA-MA hydrogel at 37 degrees C showed that EPO was released rapidly for 2 days and then slowly up to 7 days from HA-MA hydrogels. The released EPO appeared to be intact from the analysis with RP-HPLC. According to in vivo release test of EPO from HA-MA hydrogels crosslinked with the peptide linker in Sprague-Dawley (SD) rats, elevated plasma concentration of EPO was maintained up to 7 days. There was no adverse effect during and after the in vivo tests. PMID:16781096

  7. Tuning the stereoselectivity of a DNA-catalyzed michael addition through covalent modification.

    PubMed

    Dey, Surjendu; Jäschke, Andres

    2015-09-14

    Complexes of G-quadruplex DNA and Cu(II) ions have previously been applied as catalysts in asymmetric reactions, but the largely unspecific and noncovalent nature of the interaction has impeded understanding of the structural basis of catalysis. To better control the formation of a catalytically competent species, DNA quadruplexes were derivatized with linker-bpy-Cu(II) complexes in a site-specific manner and applied in asymmetric aqueous Michael additions. These modified quadruplexes exhibited high rate acceleration and stereoselectivity. Different factors were found to be important for the catalytic performance of the modified G-quadruplexes, among them, the position of modification, the topology of the quadruplex, the nature of the ligand, and the length of the linker between the ligand and DNA. Moving the same ligand by just two nucleotides inverted the stereochemical outcome: quadruplexes modified at position 10 formed the (-)-enantiomer with up to 92 % ee, while DNA derivatized at position 12 formed the (+)-enantiomer with up to 75 % ee. This stereopreference was maintained when applied to structurally different Michael acceptors. This work demonstrates a new and simple way to tune the stereoselectivity in DNA-based asymmetric catalysis.

  8. Evaluation of GPS Coverage for the X-33 Michael-6 Trajectory

    NASA Technical Reports Server (NTRS)

    Lundberg, John B.

    1998-01-01

    The onboard navigational system for the X-33 test flights will be based on the use of measurements collected from the Embedded Global Positioning System (GPS)/INS system. Some of the factors which will affect the quality of the GPS contribution to the navigational solution will be the number of pseudorange measurements collected at any instant in time, the distribution of the GPS satellites within the field of view, and the inherent noise level of the GPS receiver. The distribution of GPS satellites within the field of view of the receiver's antenna will depend on the receiver's position, the time of day, pointing direction of the antenna, and the effective cone angle of the antenna. The number of pseudorange measurements collected will depend upon these factors as well as the time required to lock onto a GPS satellite signal once the GPS satellite comes into the field of view of the antenna and the number of available receiver channels. The objective of this study is to evaluate the GPS coverage resulting from the proposed antenna pointing directions, the proposed antenna cone angles, and the effects due to the time of day for the X-33 Michael-6 trajectory from launch at Edwards AFB, California, to the start of the Terminal Area Energy Management (TAEM) phase on approach to Michael AAF, Utah.

  9. [Co-editors and editors with Jewish origins of the first German journals for anaesthesia. Their fate under National Socialism and an attempt at a biographical appreciation].

    PubMed

    Goerig, M; Goetz, A E

    2010-09-01

    The decision to publish the journals Der Schmerz and Narkose und Anaesthesie in 1928 was an important step towards the professionalization of anaesthesiology in Germany. The appearance of both journals, which for economic reasons merged into Schmerz - Narkose - Anaesthesie 1 year later, was initiated and vehemently supported by Jewish physicians. As editors and co-editors they were deeply involved with the editorial tasks of the journals for years from the early beginnings. When the National Socialistic Party took over the government in Germany many of the Jewish colleagues were forced to quit their editorial tasks, were eliminated and replaced by "Arians", they were persecuted and often arrested, forced to emigrate or decided to commit suicide due to inhumane personal circumstances. It is our intention to recall the biography and the terrible fate of the nearly unknown Jewish members of the editorial board of the first German anaesthesia journals. Moreover the biographic sketches promote a continuous discussion about the victims of an inhumane and barbarous ideology. PMID:20842476

  10. Base-dependent stereodivergent intramolecular aza-Michael reaction: asymmetric synthesis of 1,3-disubstituted isoindolines.

    PubMed

    Fustero, Santos; Herrera, Lidia; Lázaro, Ruben; Rodríguez, Elsa; Maestro, Miguel A; Mateu, Natalia; Barrio, Pablo

    2013-08-26

    The nucleophilic addition (A(N)) / intramolecular aza-Michael reaction (IMAMR) process on Ellman's tert-butylsulfinyl imines, bearing a Michael acceptor in the ortho position, is studied. This reaction affords 1,3-disubstituted isoindolines with a wide range of substituents in good yields and diastereoselectivities. Interestingly, careful choice of the base for the aza-Michael step allows either the cis or the trans diastereoisomers to be exclusively obtained. This stereodivergent cyclization has enabled the synthesis of C2-symmetric bisacetate-substituted isoindolines. In addition, bisacetate isoindolines bearing two well-differentiated ester moieties are also noteworthy because they may allow for the orthogonal synthesis of β,β'-dipeptides using a single nitrogen atom as a linchpin.

  11. Programming the Navier-Stokes computer: An abstract machine model and a visual editor

    NASA Technical Reports Server (NTRS)

    Middleton, David; Crockett, Tom; Tomboulian, Sherry

    1988-01-01

    The Navier-Stokes computer is a parallel computer designed to solve Computational Fluid Dynamics problems. Each processor contains several floating point units which can be configured under program control to implement a vector pipeline with several inputs and outputs. Since the development of an effective compiler for this computer appears to be very difficult, machine level programming seems necessary and support tools for this process have been studied. These support tools are organized into a graphical program editor. A programming process is described by which appropriate computations may be efficiently implemented on the Navier-Stokes computer. The graphical editor would support this programming process, verifying various programmer choices for correctness and deducing values such as pipeline delays and network configurations. Step by step details are provided and demonstrated with two example programs.

  12. Writing a narrative biomedical review: considerations for authors, peer reviewers, and editors.

    PubMed

    Gasparyan, Armen Yuri; Ayvazyan, Lilit; Blackmore, Heather; Kitas, George D

    2011-11-01

    Review articles comprehensively covering a specific topic are crucial for successful research and academic projects. Most editors consider review articles for special and regular issues of journals. Writing a review requires deep knowledge and understanding of a field. The aim of this review is to analyze the main steps in writing a narrative biomedical review and to consider points that may increase the chances of success. We performed a comprehensive search through MEDLINE, EMBASE, Scopus, and Web of Science using the following keywords: review of the literature, narrative review, title, abstract, authorship, ethics, peer review, research methods, medical writing, scientific writing, and writing standards. Opinions expressed in the review are also based on personal experience as authors, peer reviewers, and editors.

  13. A polystyrene-supported 9-amino(9-deoxy)epi quinine derivative for continuous flow asymmetric Michael reactions.

    PubMed

    Izquierdo, Javier; Ayats, Carles; Henseler, Andrea H; Pericàs, Miquel A

    2015-04-14

    A polystyrene (PS)-supported 9-amino(9-deoxy)epi quinine derivative catalyzes Michael reactions affording excellent levels of conversion and enantioselectivity using different nucleophiles and structurally diverse enones. The highly recyclable, immobilized catalyst has been used to implement a single-pass, continuous flow process (residence time: 40 min) that can be operated for 21 hours without significant decrease in conversion and with improved enantioselectivity with respect to batch operation. The flow process has also been used for the sequential preparation of a small library of enantioenriched Michael adducts.

  14. How is research publishing going to progress in the next 20 years?: transcription of session for editors, associate editors, publishers and others with an interest in scientific publishing held at IADR meeting in Seattle on Wednesday, 20 March 2013.

    PubMed

    Eaton, Kenneth A; Rex Holland, G; Giannobile, William V; Hancocks, Stephen; Robinson, Peter G; Lynch, Christopher D

    2014-03-01

    On March 20th 2013, a one-hour session for Editors, Associate Editors, Publishers and others with an interest in scientific publishing was held at the IADR International Session in Seattle. Organised by Kenneth Eaton and Christopher Lynch (Chair and Secretary, respectively, of the British Dental Editors Forum), the meeting sought to bring together leading international experts in dental publishing, as well as authors, reviewers and students engaged in research. The meeting was an overwhelming success, with more than 100 attendees. A panel involving four leading dental editors led a discussion on anticipated developments in publishing dental research with much involvement and contribution from audience members. This was the third such meeting held at the IADR for Editors, Associate Editors, Publishers and others with an interest in scientific publishing. A follow-up session will take place in Cape Town on 25 June 2014 as part of the annual IADR meeting. The transcript of the Seattle meeting is reproduced in this article. Where possible speakers are identified by name. At the first time of mention their role/position is also stated, thereafter only their name appears. We are grateful to Stephen Hancocks Ltd. for their generous sponsorship of this event. For those who were not able to attend the authors hope this article gives a flavour of the discussions and will encourage colleagues to attend future events. Involvement is open to Editors, Associate Editors, Publishers and others with an interest in scientific publishing. It is a very open group and all those with an interest will be welcome to join in.

  15. How is research publishing going to progress in the next 20 years? Transcription of session for editors, associate editors, publishers and others with an interest in scientific publishing held at IADR meeting in Seattle on Wednesday, 20 March 2013.

    PubMed

    Eaton, K A; Holland, G R; Giannobile, W V; Hancocks, S; Robinson, P G; Lynch, C D

    2014-05-01

    On March 20th 2013, a one-hour session for Editors, Associate Editors, Publishers and others with an interest in scientific publishing was held at the IADR International Session in Seattle. Organised by Kenneth Eaton and Chris Lynch (Chair and Secretary, respectively, of the British Dental Editors Forum), the meeting sought to bring together leading international experts in dental publishing, as well as authors, reviewers and students engaged in research. The meeting was an overwhelming success, with more than 100 attendees. A panel involving four leading dental editors led a discussion on anticipated developments in publishing dental research with much involvement and contribution from audience members. This was the third such meeting held at the IADR for Editors, Associate Editors, Publishers and others with an interest in scientific publishing. A follow up session will take place in Cape Town on 25 June 2014 as part of the annual IADR meeting. The transcript of the meeting is reproduced in this article. Where possible speakers are identified by name. At the first time of mention their role/ position is also stated, thereafter only their name appears. We are grateful to Stephen Hancocks Ltd for their generous sponsorship of this event. For those who were not able to attend the authors hope this article gives a flavour of the discussions and will encourage colleagues to attend future events. Involvement is open to Editors, Associate Editors, Publishers and others with an interest in scientific publishing. It is a very open group and all those with an interest will be welcome to join in.

  16. Conflicts of interest in biomedical publications: considerations for authors, peer reviewers, and editors.

    PubMed

    Gasparyan, Armen Yuri; Ayvazyan, Lilit; Akazhanov, Nurbek A; Kitas, George D

    2013-12-01

    This article overviews evidence on common instances of conflict of interest (COI) in research publications from general and specialized fields of biomedicine. Financial COIs are viewed as the most powerful source of bias, which may even distort citation outcomes of sponsored publications. The urge to boost journal citation indicators by stakeholders of science communication is viewed as a new secondary interest, which may compromize the interaction between authors, peer reviewers and editors. Comprehensive policies on disclosure of financial and non-financial COIs in scholarly journals are presented as proxies of their indexing in evidence-based databases, and examples of successful medical journals are discussed in detail. Reports on clinical trials, systematic reviews, meta-analyses and clinical practice guidelines may be unduly influenced by author-pharmaceutical industry relations, but these publications do not always contain explicit disclosures to allow the readers to judge the reliability of the published conclusions and practice-changing recommendations. The article emphasizes the importance of adhering to the guidance on COI from learned associations such as the International Committee of Medical Journal Editors (ICMJE). It also considers joint efforts of authors, peer reviewers and editors as a foundation for appropriately defining and disclosing potential COIs.

  17. Improving rural newspaper coverage of nutrition stories: an educational assessment of editors' attitudes and learning needs.

    PubMed

    Nothwehr, Faryle; Chrisman, Matthew; Andsager, Julie L

    2014-11-01

    Local newspapers are an important source of information for rural residents but often lack accurate or helpful nutrition-related information. To improve the quantity and quality of nutrition stories in rural, local newspapers, it is important to understand the perspective of editors. An online survey of 51 rural Midwest editors was conducted to assess attitudes toward writing nutrition stories, sources of information, perceived challenges, and interest in learning more about writing such stories. Of respondents, 49% were female, and 63% had at least a 4-year college degree. Through a mix of closed- and open-ended questions, the majority indicated positive attitudes toward nutrition stories, were confident in their abilities to write them, and expressed interest in learning more. Challenges cited include lack of print space, small staff, lack of specific requests from readers for nutrition stories, and the need to avoid offending local agricultural businesses. Results should be useful in planning an educational intervention for editors. Meanwhile, public health practitioners should provide concise press releases to their local newspapers about their activities. Also, greater expressions of appreciation from public health professionals and other readers may lead to higher prioritization of nutrition-related stories, and ultimately to an environment more supportive of healthy eating.

  18. Reply to B. Meunier's Letter to the Editor Re: Brewer G. J.; Nutrients 2015, 7, 10053-10064.

    PubMed

    Brewer, George J

    2016-01-01

    In a letter to the editor, Meunier [1] apparently attempts to discredit the copper-2 hypothesis for causation of the Alzheimer's disease (AD) epidemic in developed countries proposed by myself in a review in this journal [2].[...]. PMID:27556487

  19. Organocatalytic and enantioselective Michael reaction between α-nitroesters and nitroalkenes. Syn/anti-selectivity control using catalysts with the same absolute backbone chirality.

    PubMed

    Martínez, Jose I; Uria, Uxue; Muñiz, Maria; Reyes, Efraím; Carrillo, Luisa; Vicario, Jose L

    2015-01-01

    The asymmetric and catalytic Michael reaction between α-nitroesters and nitroalkenes has been studied in the presence of two bifunctional catalysts both containing the same absolute chirality at the carbon backbone. The reaction performed in similar conditions allows us to control the syn or anti selectivity of the Michael adduct obtaining good yields and high enantiocontrol in all cases.

  20. Science against modernism: the relevance of the social theory of Michael Polanyi.

    PubMed

    Thorpe, C

    2001-03-01

    Science, as an institution, is widely taken by sociologists to exemplify the modern tendency towards vesting trust and authority in impersonal offices and procedures, rather than in embodied human individuals. Such views of science face an important challenge in the social philosophy of Michael Polanyi. His work provides important insights into the continuing role of embodied personal authority and tradition in science and, hence, in late modernity. I explicate Polanyi's relevance for social theory, through a comparison with Weber's essay 'Science as a Vocation'. An understanding of the personal dimensions of trust and authority in science suggests practical limits to the position of Giddens on the disembedding of social relations and on the scepticism and reflexivity of modernity.

  1. Carbocations as Lewis acid catalysts in Diels-Alder and Michael addition reactions.

    PubMed

    Bah, Juho; Franzén, Johan

    2014-01-20

    In general, Lewis acid catalysts are metal-based compounds that owe their reactivity to a low-lying empty orbital. However, one potential Lewis acid that has received negligible attention as a catalyst is the carbocation. We have demonstrated the potential of the carbocation as a highly powerful Lewis acid catalyst for organic reactions. The stable and easily available triphenylmethyl (trityl) cation was found to be a highly efficient catalyst for the Diels-Alder reaction for a range of substrates. Catalyst loadings as low as 500 ppm, excellent yields, and good endo/exo selectivities were achieved. Furthermore, by changing the electronic properties of the substituents on the tritylium ion, the Lewis acidity of the catalyst could be tuned to control the outcome of the reaction. The ability of this carbocation as a Lewis acid catalyst was also further extended to the Michael reaction.

  2. Michael Reaction of 3-aAryl-2,4-Dicarboethoxy-5-Hydroxy-5-Methylcyclohexanones

    PubMed Central

    El-Ablack, Fawzia Zakaria; Metwally, M. A.; Khalil, A. M.

    2015-01-01

    Summary The reaction of 3-aryl-2,4-dicarboethoxy-5-hydroxy-5-methylcyclohexanones 1with benzalacetone, dibenzalacetone, benzalacetophenone, and 4-benzal-1-phenyl-3-methyl pyrazolone has been investigated to give Michael compounds 2-5. hydrolysis of the dioxo derivative 4 afforded1,5-dicarbonyl derivative 6which On condensation with hydrazine and/or substituted hydrazine and hydroxylamine produced1,2-diazepine and 1,2-oxazepine derivatives 7,8 respectively. Reaction of β-Keto ester 1 with 1,3-diphenylacetone afforded 9. The structures of the hitherto unknown compounds have been confirmed by analytical and spectral data. The newly synthesized compounds have been screened to test their antimicrobial and antifungal activity. PMID:26689538

  3. Effect of method of heterogenization of ephedrine and reaction conditions on the enantioselectivity of Michael additions

    SciTech Connect

    Krotov, V.V.; Staroverov, S.M.; Nesterenko, P.N.; Lisichkin. G.V.

    1987-11-10

    A series of heterogeneous catalysts for asymmetric Michael additions was synthesized based on ephedrine chemically bound to the surface of silica. The length of the hydrocarbon chain binding the active center to the support surface affects the sign of rotation of the reaction product from the asymmetric addition of thiophenol to benzylideneacetophenone. Grafting ephedrine to the silica surface via a short hydrocarbon chain results in a change in the configuration of the reaction product. Silanol groups on the silica surface are involved in the transition state, as evidenced by data obtained using silica which has been exhaustively treated with trimethylchlorosilane. The absolute specific rotation of 1,3-diphenyl-3-thiophenylpropan-1-one has been established.

  4. Science against modernism: the relevance of the social theory of Michael Polanyi.

    PubMed

    Thorpe, C

    2001-03-01

    Science, as an institution, is widely taken by sociologists to exemplify the modern tendency towards vesting trust and authority in impersonal offices and procedures, rather than in embodied human individuals. Such views of science face an important challenge in the social philosophy of Michael Polanyi. His work provides important insights into the continuing role of embodied personal authority and tradition in science and, hence, in late modernity. I explicate Polanyi's relevance for social theory, through a comparison with Weber's essay 'Science as a Vocation'. An understanding of the personal dimensions of trust and authority in science suggests practical limits to the position of Giddens on the disembedding of social relations and on the scepticism and reflexivity of modernity. PMID:11321228

  5. STS-113 M.S. Michael Lopez-Alegriain White Room before launch

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. -- In the White Room on Launch Pad 39A, STS-113 Mission Specialist Michael Lopez-Alegria is helped with his launch and entry suit before entering Space Shuttle Endeavour. Closeout Crew members helping are (from left) Rick Welty, United Space Alliance Vehicle Closeout chief, Bobby Wright, USA mechanical technician, and Danny Wyatt, NASA Quality Assurance specialist. The launch will carry the Expedition 6 crew to the Station and return the Expedition 5 crew to Earth. The major objective of the mission is delivery of the Port 1 (P1) Integrated Truss Assembly, which will be attached to the port side of the S0 truss. Three spacewalks are planned to install and activate the truss and its associated equipment. Launch of Space Shuttle Endeavour on mission STS-113 is scheduled for Nov. 23 at 7:50 p.m. EST.

  6. STS-113 M.S. Michael Lopez-Alegria suits up for the second launch attempt

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - STS-113 Mission Specialist Michael Lopez-Alegria suits up for the second launch attempt of mission STS-113. The previous launch on Nov. 22 was scrubbed due to poor weather conditions at the Transoceanic Abort Landing sites. He will be making his third Shuttle flight. The launch will carry the Expedition 6 crew to the Station and return the Expedition 5 crew to Earth. The major objective of the mission is delivery of the Port 1 (P1) Integrated Truss Assembly, which will be attached to the port side of the S0 truss. Three spacewalks are planned to install and activate the truss and its associated equipment. Launch of Space Shuttle Endeavour on mission STS-113 is now scheduled for Nov. 23 at 7:50 p.m. EST.

  7. STS-92 M.S. Michael Lopez-Alegria suits up for launch

    NASA Technical Reports Server (NTRS)

    2000-01-01

    During suitup in the Operations and Checkout Building, STS-92 Mission Specialist Michael E. Lopez-Alegria smiles and clasps his hands in anticipation of a second launch attempt. He and the rest of the crew will be heading out to the Astrovan for the ride to Launch Pad 39A. During the 11-day mission to the International Space Station, four extravehicular activities (EVAs), or spacewalks, are planned for construction. The payload includes the Integrated Truss Structure Z-1 and the third Pressurized Mating Adapter. The Z-1 truss is the first of 10 that will become the backbone of the Space Station, eventually stretching the length of a football field. PMA-3 will provide a Shuttle docking port for solar array installation on the sixth Station flight and Lab installation on the seventh Station flight. Launch is scheduled for 7:17 p.m. EDT. Landing is expected Oct. 22 at 2:10 p.m. EDT.

  8. STS-113 M.S. Michael Lopez-Alegria arrives at KSC for launch

    NASA Technical Reports Server (NTRS)

    2002-01-01

    KENNEDY SPACE CENTER, FLA. - STS-113 Mission Specialist Michael Lopez-Alegria arrives at the KSC Shuttle Landing Facility to get ready for launch. STS-113 is the 16th American assembly flight to the International Space Station. The primary mission is bringing the Expedition 6 crew to the Station and returning the Expedition 5 crew to Earth. The major objective of the mission is delivery of the Port 1 (P1) Integrated Truss Assembly, which will be attached to the port side of the S0 truss. Three spacewalks are planned to install and activate the truss and its associated equipment. Launch of Space Shuttle Endeavour on mission STS-113 is scheduled for Nov. 11 between midnight and 4 a.m. EST.

  9. STS-113 Crew Interviews: Michael Lopez-Alegria, Mission Specialist 1

    NASA Technical Reports Server (NTRS)

    2002-01-01

    STS-113 Mission Specialist 1 Michael Lopez-Alegria is seen during this preflight interview where he gives a quick overview of the mission before answering questions about his inspiration to become an astronaut and his career path. Lopez-Alegria outlines his role in the mission in general, and specifically during the docking and extravehicular activities (EVAs). He describes the payload (P1 truss) and the crew transfer activities (the crew of Expedition Six is replacing the crew of Expedition Five on the International Space Station (ISS)). Lopez-Alegria discusses the planned EVAs in detail and outlines what supplies will be left for the resident crew. He ends with his thoughts on the importance of the ISS as the second anniversary of human occupation of the Space Station approaches.

  10. Michael Faraday on the Learning of Science and Attitudes of Mind

    NASA Astrophysics Data System (ADS)

    Crawford, Elspeth

    The paper makes use of Michael Faraday's ideas about learning, in particular his thoughts about attitudes to the unknowns of science and the development of an attitude which improves scientific decision-making. An invented scenario involving nursery school children demonstrates some attitudes displayed there. Discussion of the scenario and variation in possible outcomes suggests that Faraday's views are relevant to scientific learning in general. The main thesis of the paper is that it is central to learning in science to acknowledge that there is an inner struggle involved in facing unknowns, and that empathy with the fears and expectations of learners is an essential quality if genuinely scientific thought is to develop. It is suggested, following Faraday, that understanding our own feelings while we teach is a pre-requisite to enabling such empathy and that only then will we be in a position to evaluate accurately whether or not our pupils are thinking scientifically.

  11. Insights on the Application of the Retro Michael-Type Addition on Maleimide-Functionalized Gold Nanoparticles in Biology and Nanomedicine.

    PubMed

    Weissman, Max R; Winger, Kathleen T; Ghiassian, Sara; Gobbo, Pierangelo; Workentin, Mark S

    2016-03-16

    The glutathione-mediated retro Michael-type addition reaction is demonstrated to take place at the interface of small water-soluble maleimide-functionalized gold nanoparticles (Maleimide-AuNP). The retro Michael-type addition reaction can be blocked by hydrolyzing the Michael addition thioether adduct at the nanoparticle's interface under reaction conditions that do not cause AuNP decomposition. This procedure "locks" the molecule of interest onto the Maleimide-AuNP template for potential uses in medical imaging and bioconjugation, ensuring no loss of the molecular cargo from the nanocarrier. On the other hand, the glutathione-mediated retro Michael-type addition reaction can be exploited for delivering a molecular payload. As a proof of concept, a fluorogenic molecular cargo was incorporated onto a Maleimide-AuNP and delivered via the glutathione-mediated retro Michael-type addition reaction.

  12. Sight, Sound, and Knowledge: Michael Polanyi's Epistemology as an Attempt to Redress the Sensory Imbalance in Modern Western Thought

    ERIC Educational Resources Information Center

    Jardine, Murray

    2011-01-01

    The author argues that Michael Polanyi's philosophy of science can be understood as an (unconscious) attempt to recapture elements of experience largely forgotten or repressed in modernity. Specifically, the author argues that Polanyi's epistemology appears to draw on elements of oral-aural experience that have been relatively ignored by the…

  13. Attending to hidden realities: contributions from the work of Michael Polanyi to supervision in pastoral care and counseling.

    PubMed

    Rodgerson, Thomas E

    2008-01-01

    In this article, the author suggests that concepts from the work of Michael Polanyi--such as the tacit dimension, subsidiary awareness, and commitment to a yet unrevealed, hidden reality--provide a theoretical basis for understanding the unique formation involved in pastoral care and counseling supervision.

  14. Effective Integration of Technology and Instruction. Q&A with Michael Jay. REL Mid-Atlantic Educator Effectiveness Webinar Series

    ERIC Educational Resources Information Center

    Regional Educational Laboratory Mid-Atlantic, 2015

    2015-01-01

    In this webinar, long-time educator and developer of education technology Michael Jay discussed the importance of using technology to support learning and gave examples of how teachers can integrate technology into their instruction based on the Common Core State Standards and the Next Generation Science Standards. The PowerPoint presentation and…

  15. Highly enantioselective Michael addition reactions of 2-substituted benzofuran-3(2H)-ones to nitroolefins.

    PubMed

    Zhang, Zhi-Pei; Dong, Nan; Li, Xin; Cheng, Jin-Pei

    2015-10-21

    A highly enantioselective Michael addition reaction of 2-substituted benzofuran-3(2H)-ones to nitroolefins was promoted by a bifunctional squaramide catalyst. As a result, a number of chiral 2,2'-substituted benzofuran-3-one derivatives, bearing adjacent quaternary-tertiary stereocenters, were efficiently synthesized with excellent enantioselectivities.

  16. Enantioselective synthesis of benzofurans and benzoxazines via an olefin cross-metathesis-intramolecular oxo-Michael reaction.

    PubMed

    Zhang, Jun-Wei; Cai, Quan; Gu, Qing; Shi, Xiao-Xin; You, Shu-Li

    2013-09-11

    Chiral phosphoric acid and Hoveyda-Grubbs II were found to catalyze an olefin cross-metathesis-intramolecular oxo-Michael cascade reaction of the ortho-allylphenols and enones to provide a variety of benzofuran and benzoxazine derivatives in moderate to good yields and enantioselectivity. PMID:23884172

  17. 78 FR 2391 - CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v. Pacific Gas and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission CAlifornians for Renewable Energy, Inc., Michael E. Boyd, Robert M. Sarvey v... and Procedure of the Federal Energy Regulatory Commission (FERC); CAlifornians for Renewable...

  18. A Symposium on the Relevance of Michael Polanyi's Insights to a Reformulated Understanding of Science, Technology, and Society

    ERIC Educational Resources Information Center

    Mead, Walter B.

    2011-01-01

    This is intended as an introductory statement to the explorations undertaken in the essays that follow. The authors of these essays attempt to introduce the reader to some of the insights of Michael Polanyi and their implications for the reader who wishes to come to a greater understanding of modern technological society, which--for better or…

  19. Enantioselective synthesis of benzofurans and benzoxazines via an olefin cross-metathesis-intramolecular oxo-Michael reaction.

    PubMed

    Zhang, Jun-Wei; Cai, Quan; Gu, Qing; Shi, Xiao-Xin; You, Shu-Li

    2013-09-11

    Chiral phosphoric acid and Hoveyda-Grubbs II were found to catalyze an olefin cross-metathesis-intramolecular oxo-Michael cascade reaction of the ortho-allylphenols and enones to provide a variety of benzofuran and benzoxazine derivatives in moderate to good yields and enantioselectivity.

  20. Antimicrobial and antifouling hydrogels formed in situ from polycarbonate and poly(ethylene glycol) via Michael addition.

    PubMed

    Liu, Shao Qiong; Yang, Chuan; Huang, Yuan; Ding, Xin; Li, Yan; Fan, Wei Min; Hedrick, James L; Yang, Yi-Yan

    2012-12-18

    A novel class of antimicrobial cationic polycarbonate/PEG hydrogels are designed and synthesized by Michael addition chemistry. These hydrogels demonstrate strong broad-spectrum antimicrobial activities against various clinically isolated multidrug-resistant microbes. Moreover, they exhibit nonfouling properties and prevent the substrate from microbial adhesion. These antimicrobial and antifouling gels are promising materials as catheter coatings and wound dressings to prevent infections.