Sample records for n-csr certified shareholder

  1. 17 CFR 274.128 - Form N-CSR, certified shareholder report.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-CSR, certified... Form N-CSR, certified shareholder report. This form shall be used by registered management investment... Form N-CSR, see the List of CFR Sections Affected, which appears in the Finding Aids section of the...

  2. 17 CFR 274.128 - Form N-CSR, certified shareholder report.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form N-CSR, certified... Form N-CSR, certified shareholder report. This form shall be used by registered management investment... Form N-CSR, see the List of CFR Sections Affected, which appears in the Finding Aids section of the...

  3. 17 CFR 249.331 - Form N-CSR, certified shareholder report.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form N-CSR, certified shareholder report. 249.331 Section 249.331 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Required Under Sections 13 and 15(d) of the Securities Exchange Act of 1934 § 249.331 Form N-CSR, certified...

  4. 17 CFR 249.331 - Form N-CSR, certified shareholder report.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Form N-CSR, certified shareholder report. 249.331 Section 249.331 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Required Under Sections 13 and 15(d) of the Securities Exchange Act of 1934 § 249.331 Form N-CSR, certified...

  5. 75 FR 27927 - Diversification Requirements for Certain Defined Contribution Plans

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-05-19

    ... section 414(l) with respect to any other defined benefit plan or defined contribution plan maintained by... disclosure of the fund's portfolio holdings (for example, Form N-CSR, ``Certified Shareholder Report of... securities, as well as a direct or indirect benefit that is conditioned on investment in employer securities...

  6. 78 FR 43250 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-19

    ... combined reporting form used by registered management investment companies (``funds'') to file certified shareholder reports under the Investment Company Act of 1940 (15 U.S.C. 80a-1 et seq.) (``Investment Company...''). Specifically, Form N-CSR is to be used for reports under section 30(b)(2) of the Investment Company Act (15 U.S...

  7. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., at the time of filing of the report must sign a certification. (b) Each report on Form N-CSR filed by... company (or equivalent thereof) must sign a certification. This requirement may be satisfied by a single... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter...

  8. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ..., at the time of filing of the report must sign a certification. (b) Each report on Form N-CSR filed by... company (or equivalent thereof) must sign a certification. This requirement may be satisfied by a single... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter...

  9. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... and Form N-Q. 270.30a-2 Section 270.30a-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter) or Form N-Q (§§ 249.332 and 274.130 of this chapter) by a registered management investment company...

  10. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... and Form N-Q. 270.30a-2 Section 270.30a-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter) or Form N-Q (§§ 249.332 and 274.130 of this chapter) by a registered management investment company...

  11. 17 CFR 270.30a-2 - Certification of Form N-CSR and Form N-Q.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... and Form N-Q. 270.30a-2 Section 270.30a-2 Commodity and Securities Exchanges SECURITIES AND EXCHANGE... Form N-CSR and Form N-Q. (a) Each report filed on Form N-CSR (§§ 249.331 and 274.128 of this chapter) or Form N-Q (§§ 249.332 and 274.130 of this chapter) by a registered management investment company...

  12. Examination of Csr regulatory circuitry using epistasis analysis with RNA-seq (Epi-seq) confirms that CsrD affects gene expression via CsrA, CsrB and CsrC.

    PubMed

    Potts, Anastasia H; Leng, Yuanyuan; Babitzke, Paul; Romeo, Tony

    2018-03-29

    The Csr global regulatory system coordinates gene expression in response to metabolic status. This system utilizes the RNA binding protein CsrA to regulate gene expression by binding to transcripts of structural and regulatory genes, thus affecting their structure, stability, translation, and/or transcription elongation. CsrA activity is controlled by sRNAs, CsrB and CsrC, which sequester CsrA away from other transcripts. CsrB/C levels are partly determined by their rates of turnover, which requires CsrD to render them susceptible to RNase E cleavage. Previous epistasis analysis suggested that CsrD affects gene expression through the other Csr components, CsrB/C and CsrA. However, those conclusions were based on a limited analysis of reporters. Here, we reassessed the global behavior of the Csr circuitry using epistasis analysis with RNA seq (Epi-seq). Because CsrD effects on mRNA levels were entirely lost in the csrA mutant and largely eliminated in a csrB/C mutant under our experimental conditions, while the majority of CsrA effects persisted in the absence of csrD, the original model accounts for the global behavior of the Csr system. Our present results also reflect a more nuanced role of CsrA as terminal regulator of the Csr system than has been recognized.

  13. Regulatory Interactions of Csr Components: the RNA Binding Protein CsrA Activates csrB Transcription in Escherichia coli

    PubMed Central

    Gudapaty, Seshagirirao; Suzuki, Kazushi; Wang, Xin; Babitzke, Paul; Romeo, Tony

    2001-01-01

    The global regulator CsrA (carbon storage regulator) of Escherichia coli is a small RNA binding protein that represses various metabolic pathways and processes that are induced in the stationary phase of growth, while it activates certain exponential phase functions. Both repression and activation by CsrA involve posttranscriptional mechanisms, in which CsrA binding to mRNA leads to decreased or increased transcript stability, respectively. CsrA also binds to a small untranslated RNA, CsrB, forming a ribonucleoprotein complex, which antagonizes CsrA activity. We have further examined the regulatory interactions of CsrA and CsrB RNA. The 5′ end of the CsrB transcript was mapped, and a csrB::cam null mutant was constructed. CsrA protein and CsrB RNA levels were estimated throughout the growth curves of wild-type and isogenic csrA, csrB, rpoS, or csrA rpoS mutant strains. CsrA levels exhibited modest or negligible effects of these mutations. The intracellular concentration of CsrA exceeded the total CsrA-binding capacity of intracellular CsrB RNA. In contrast, CsrB levels were drastically decreased (∼10-fold) in the csrA mutants. CsrB transcript stability was unaffected by csrA. The expression of a csrB-lacZ transcriptional fusion containing the region from −242 to +4 bp of the csrB gene was decreased ∼20-fold by a csrA::kanR mutation in vivo but was unaffected by CsrA protein in vitro. These results reveal a significant, though most likely indirect, role for CsrA in regulating csrB transcription. Furthermore, our findings suggest that CsrA mediates an intriguing form of autoregulation, whereby its activity, but not its levels, is modulated through effects on an RNA antagonist, CsrB. PMID:11567002

  14. Identification of a Csr system in Serratia marcescens 2170.

    PubMed

    Ito, Manabu; Nomura, Kazuki; Sugimoto, Hayuki; Watanabe, Takeshi; Suzuki, Kazushi

    2014-01-01

    The carbon storage regulator (Csr) global regulatory system is conserved in many eubacteria and coordinates the expression of various genes that facilitate adaptation during the major physiological growth phase. The Csr system in Escherichia coli comprises an RNA-binding protein, CsrA; small non-coding RNAs, CsrB and CsrC; and a decay factor for small RNAs, CsrD. In this study, we identified the Csr system in Serratia marcescens 2170. S. marcescens CsrA was 97% identical to E. coli CsrA. CsrB and CsrC RNAs had typical stem-loop structures, including a GGA motif that is the CsrA binding site. CsrD was composed of N-terminal two times transmembrane region and HAMP-like, GGDEF, and EAL domains. Overexpression of S. marcescens csr genes complemented the phenotype of E. coli csr mutants. S. marcescens CsrD affected the decay of CsrB and CsrC RNAs in E. coli. These results suggest that the Csr system in S. marcescens is composed of an RNA-binding protein, two Csr small RNAs, and a decay factor for Csr small RNAs.

  15. Shareholder interests and utility competition

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Studness, C.M.

    1995-03-15

    The process of determining how to implement utility competition is often cast as a struggle between two opposing camps: shareholders and ratepayers. There are, of course, two other major players, management and regulators. The bipolar view tacitly assumes that shareholder and management interests coincide and that regulators have customer interests at heart. Neither assumption is valid. Shareholder interests deviate from management interests in important ways, just as the interests of the entrenched regulatory bureaucracy diverge from the public interest. Therefore, shareholder and management interests must be considered separately. In the past, managements have often pursued their own interests, with devastatingmore » financial impact on shareholders. Competition offers shareholders an opportunity to increase their leverage over managements, thereby increasing their returns as well.« less

  16. 75 FR 64120 - Technical Amendments to Forms N-CSR and N-SAR in Connection With the Comprehensive Iran Sanctions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-19

    ...] Technical Amendments to Forms N-CSR and N-SAR in Connection With the Comprehensive Iran Sanctions... the Comprehensive Iran Sanctions, Accountability, and Divestment Act of 2010. DATES: Effective Date... Iran Sanctions, Accountability, and Divestment Act of 2010 (``Iran Divestment Act'') into law.\\5\\ Among...

  17. Shareholding Networks in Japan

    NASA Astrophysics Data System (ADS)

    Souma, Wataru; Fujiwara, Yoshi; Aoyama, Hideaki

    2005-06-01

    The Japanese shareholding network existing at the end of March 2002 is studied empirically. The network is constructed from 2,303 listed companies and 53 non-listed financial institutions. We consider this network as a directed graph by drawing edges from shareholders to stock corporations. The lengths of the shareholder lists vary with the companies, and the most comprehensive lists contain the top 30 shareholders. Consequently, the distribution of incoming edges has an upper bound, while that of outgoing edges has no bound. The distribution of outgoing degrees is well explained by the power law function with an exponential tail. The exponent in the power law range is γ = 1.7. To understand these features from the viewpoint of a company's growth, we consider the correlations between the outgoing degree and the company's age, profit, and total assets.

  18. On the topological properties of the cross-shareholding networks of listed companies in China: Taking shareholders’ cross-shareholding relationships into account

    NASA Astrophysics Data System (ADS)

    Li, Huajiao; An, Haizhong; Gao, Xiangyun; Huang, Jiachen; Xu, Qun

    2014-07-01

    Shareholders are the owners of listed companies, and their relationships can directly affect the structure of the stock market. In this paper, we analyze the topological properties and evolution of the cross-shareholding networks of listed companies in the past 5 years in China from 2007 to 2011, an infrequently considered topic, by taking shareholders' cross-shareholding relationships into account. This analysis arrives at a deeper insight into the inner characteristics of China's stock market. We find that the cross-shareholding networks of listed companies with shareholders' cross-shareholding relationships display statistical features that reveal the stock market's complex relationships more precisely. In particular, the results show that when the shareholders' cross-shareholding relationships are considered, first, the In-degree and Out-degree of the cross-shareholding networks follow power-law distribution and the R2 of the linear regression analysis of the cumulative degree distribution is relatively higher; second, the modularity of the communities is larger; finally, both the number of members of top-ranked communities and the number of communities that have a large number of members are larger than those of which only considering the relationships between shareholders and listed companies are taken into account. Such cross-shareholding networks analysis taking shareholders' cross-shareholding relations into account would be a helpful tool for supervisory departments and for stock market researchers to grasp the inner cross-shareholding relationships of listed companies in China, and it will be also helpful for the further researches about the "agent problems" in the stock markets from a whole point of view.

  19. Regulatory Circuitry of the CsrA/CsrB and BarA/UvrY Systems of Escherichia coli

    PubMed Central

    Suzuki, Kazushi; Wang, Xin; Weilbacher, Thomas; Pernestig, Anna-Karin; Melefors, Öjar; Georgellis, Dimitris; Babitzke, Paul; Romeo, Tony

    2002-01-01

    The global regulator CsrA (carbon storage regulator) is an RNA binding protein that coordinates central carbon metabolism, activates flagellum biosynthesis and motility, and represses biofilm formation in Escherichia coli. CsrA activity is antagonized by the untranslated RNA CsrB, to which it binds and forms a globular ribonucleoprotein complex. CsrA indirectly activates csrB transcription, in an apparent autoregulatory mechanism. In the present study, we elucidate the intermediate regulatory circuitry of this system. Mutations affecting the BarA/UvrY two-component signal transduction system decreased csrB transcription but did not affect csrA′-′lacZ expression. The uvrY defect was severalfold more severe than that of barA. Both csrA and uvrY were required for optimal barA expression. The latter observation suggests an autoregulatory loop for UvrY. Ectopic expression of uvrY suppressed the csrB-lacZ expression defects caused by uvrY, csrA, or barA mutations; csrA suppressed csrA or barA defects; and barA complemented only the barA mutation. Purified UvrY protein stimulated csrB-lacZ expression approximately sixfold in S-30 transcription-translation reactions, revealing a direct effect of UvrY on csrB transcription. Disruption of sdiA, which encodes a LuxR homologue, decreased the expression of uvrY′-′lacZ and csrB-lacZ fusions but did not affect csrA′-′lacZ. The BarA/UvrY system activated biofilm formation. Ectopic expression of uvrY stimulated biofilm formation by a csrB-null mutant, indicative of a CsrB-independent role for UvrY in biofilm development. Collectively, these results demonstrate that uvrY resides downstream from csrA in a signaling pathway for csrB and that CsrA stimulates UvrY-dependent activation of csrB expression by BarA-dependent and -independent mechanisms. PMID:12193630

  20. 12 CFR 239.26 - Shareholders.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Shareholders. 239.26 Section 239.26 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Subsidiary Holding Companies § 239.26 Shareholders. (a...

  1. 12 CFR 239.26 - Shareholders.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Shareholders. 239.26 Section 239.26 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Subsidiary Holding Companies § 239.26 Shareholders. (a...

  2. 12 CFR 239.26 - Shareholders.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 4 2012-01-01 2012-01-01 false Shareholders. 239.26 Section 239.26 Banks and Banking FEDERAL RESERVE SYSTEM (CONTINUED) BOARD OF GOVERNORS OF THE FEDERAL RESERVE SYSTEM (CONTINUED) MUTUAL HOLDING COMPANIES (REGULATION MM) Subsidiary Holding Companies § 239.26 Shareholders. (a...

  3. 10 ways to create shareholder value.

    PubMed

    Rappaport, Alfred

    2006-09-01

    Executives have developed tunnel vision in their pursuit of shareholder value, focusing on short-term performance at the expense of investing in long-term growth. It's time to broaden that perspective and begin shaping business strategies in light of the competitive landscape, not the shareholder list. In this article, Alfred Rappaport offers ten basic principles to help executives create lasting shareholder value. For starters, companies should not manage earnings or provide earnings guidance; those that fail to embrace this first principle of shareholder value will almost certainly be unable to follow the rest. Additionally, leaders should make strategic decisions and acquisitions and carry assets that maximize expected value, even if near-term earnings are negatively affected as a result. During times when there are no credible value-creating opportunities to invest in the business, companies should avoid using excess cash to make investments that look good on the surface but might end up destroying value, such as ill-advised, overpriced acquisitions. It would be better to return the cash to shareholders in the form of dividends and buybacks. Rappaport also offers guidelines for establishing effective pay incentives at every level of management; emphasizes that senior executives need to lay their wealth on the line just as shareholders do; and urges companies to embrace full disclosure, an antidote to short-term earnings obsession that serves to lessen investor uncertainty, which could reduce the cost of capital and increase the share price. The author notes that a few types of companies--high-tech start-ups, for example, and severely capital-constrained organizations--cannot afford to ignore market pressures for short-term performance. Most companies with a sound, well-executed business model, however, could better realize their potential for creating shareholder value by adopting the ten principles.

  4. Minority shareholder claims foul at Stone & Webster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krizan, W.G.

    1994-05-09

    An activist minority shareholder is trying to shake up the management of one of the industry`s oldest firms, New York City-based engineering-constructor Stone & Webster Inc., The shareholder has filed a lawsuit against the 105-year-old firm, claiming that it is understanding losses from construction activities and is using the voting rights of employee-owned stock to perpetuate current management to the detriment of all shareholders.

  5. Visual analysis and exploration of complex corporate shareholder networks

    NASA Astrophysics Data System (ADS)

    Tekušová, Tatiana; Kohlhammer, Jörn

    2008-01-01

    The analysis of large corporate shareholder network structures is an important task in corporate governance, in financing, and in financial investment domains. In a modern economy, large structures of cross-corporation, cross-border shareholder relationships exist, forming complex networks. These networks are often difficult to analyze with traditional approaches. An efficient visualization of the networks helps to reveal the interdependent shareholding formations and the controlling patterns. In this paper, we propose an effective visualization tool that supports the financial analyst in understanding complex shareholding networks. We develop an interactive visual analysis system by combining state-of-the-art visualization technologies with economic analysis methods. Our system is capable to reveal patterns in large corporate shareholder networks, allows the visual identification of the ultimate shareholders, and supports the visual analysis of integrated cash flow and control rights. We apply our system on an extensive real-world database of shareholder relationships, showing its usefulness for effective visual analysis.

  6. CSR Model Implementation from School Stakeholder Perspectives

    ERIC Educational Resources Information Center

    Herrmann, Suzannah

    2006-01-01

    Despite comprehensive school reform (CSR) model developers' best intentions to make school stakeholders adhere strictly to the implementation of model components, school stakeholders implementing CSR models inevitably make adaptations to the CSR model. Adaptations are made to CSR models because school stakeholders internalize CSR model practices…

  7. The CsrR/CsrS two-component system of group A Streptococcus responds to environmental Mg2+.

    PubMed

    Gryllos, Ioannis; Levin, James C; Wessels, Michael R

    2003-04-01

    Group A streptococci control expression of key virulence determinants via the two-component sensorregulator system CsrRCsrS. The membrane-bound sensor CsrS is thought to respond to previously unknown environmental signal(s) by controlling phosphorylation of its cognate regulator component CsrR. Phosphorylation of CsrR increases its affinity for binding to the promoter regions of Csr-regulated genes to repress transcription. Here we show that environmental Mg(2+) concentration is a potent and specific stimulus for CsrRCsrS-mediated regulation. We studied the effect of divalent cations on expression of the Csr-regulated hyaluronic acid capsule genes (hasABC) by measuring chloramphenicol acetyltransferase (CAT) activity in a reporter strain of group A Streptococcus carrying a has operon promoter-cat fusion. Addition of Mg(2+), but not of Ca(2+), Mn(2+), or Zn(2+), repressed capsule gene expression by up to 80% in a dose-dependent fashion. The decrease in capsule gene transcription was associated with a marked reduction in cell-associated capsular polysaccharide. RNA hybridization analysis demonstrated reduced expression of the Csr-regulated hasABC operon, streptokinase (ska), and streptolysin S (sagA) during growth in the presence of 15 mM Mg(2+) for the wild-type strain 003CAT but not for an isogenic csrS mutant. We propose that Mg(2+) binds to CsrS to induce phosphorylation of CsrR and subsequent repression of virulence gene expression. The low concentration of Mg(2+) in extracellular body fluids predicts that the CsrRCsrS system is maintained in the inactive state during infection, thereby allowing maximal expression of critical virulence determinants in the human host.

  8. 17 CFR 240.14a-17 - Electronic shareholder forums.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Electronic shareholder forums... Securities Exchange Act of 1934 Regulation 14a: Solicitation of Proxies § 240.14a-17 Electronic shareholder... establish, maintain, or operate an electronic shareholder forum to facilitate interaction among the...

  9. 17 CFR 240.14a-17 - Electronic shareholder forums.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Electronic shareholder forums... Securities Exchange Act of 1934 Regulation 14a: Solicitation of Proxies § 240.14a-17 Electronic shareholder... establish, maintain, or operate an electronic shareholder forum to facilitate interaction among the...

  10. 17 CFR 240.14a-17 - Electronic shareholder forums.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Electronic shareholder forums... Securities Exchange Act of 1934 Regulation 14a: Solicitation of Proxies § 240.14a-17 Electronic shareholder... establish, maintain, or operate an electronic shareholder forum to facilitate interaction among the...

  11. 17 CFR 240.14a-17 - Electronic shareholder forums.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Electronic shareholder forums... Securities Exchange Act of 1934 Regulation 14a: Solicitation of Proxies § 240.14a-17 Electronic shareholder... establish, maintain, or operate an electronic shareholder forum to facilitate interaction among the...

  12. CONDITIONS FOR CSR MICROBUNCHING GAIN SUPPRESSION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tsai, Cheng Ying; Douglas, David R.; Li, Rui

    The coherent synchrotron radiation (CSR) of a high brightness electron beam traversing a series of dipoles, such as transport arcs, may result in phase space degradation. On one hand, the CSR can perturb electron transverse motion in dispersive regions along the beamline, causing emittance growth. On the other hand, the CSR effect on the longitudinal beam dynamics could result in microbunching gain enhancement. For transport arcs, several schemes have been proposed* to suppress the CSR-induced emittance growth. Similarly, several scenarios have been introduced** to suppress CSR-induced microbunching gain, which however mostly aim for linac-based machines. In this paper we trymore » to provide sufficient conditions for suppression of CSR-induced microbunching gain along a transport arc, analogous to*. Several example lattices are presented, with the relevant microbunching analyses carried out by our semi-analytical Vlasov solver***. The simulation results show that lattices satisfying the proposed conditions indeed have microbunching gain suppressed. We expect this analysis can shed light on lattice design approach that could suppress the CSR-induced microbunching gain.« less

  13. 12 CFR 7.2001 - Notice of shareholders' meetings.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AND OPERATIONS Corporate Practices § 7.2001 Notice of shareholders' meetings. A national bank must... notice of the shareholder's meeting. The articles of association, bylaws, or law applicable to a national...

  14. The ribonucleoprotein Csr network.

    PubMed

    Seyll, Ethel; Van Melderen, Laurence

    2013-11-08

    Ribonucleoprotein complexes are essential regulatory components in bacteria. In this review, we focus on the carbon storage regulator (Csr) network, which is well conserved in the bacterial world. This regulatory network is composed of the CsrA master regulator, its targets and regulators. CsrA binds to mRNA targets and regulates translation either negatively or positively. Binding to small non-coding RNAs controls activity of this protein. Expression of these regulators is tightly regulated at the level of transcription and stability by various global regulators (RNAses, two-component systems, alarmone). We discuss the implications of these complex regulations in bacterial adaptation.

  15. 26 CFR 1.815-2 - Distributions to shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....815-2 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Distributions to Shareholders § 1.815-2 Distributions to shareholders. (a) In general. Section 815 provides that every stock life insurance company subject to the tax imposed by...

  16. Measuring Credibility Perceptions in CSR Communication: A Scale Development to Test Readers’ Perceived Credibility of CSR Reports

    PubMed Central

    Lock, Irina; Seele, Peter

    2017-01-01

    Credibility is central to communication but often jeopardized by “credibility gaps.” This is especially true for communication about corporate social responsibility (CSR). To date, no tool has been available to analyze stakeholders’ credibility perceptions of CSR communication. This article presents a series of studies conducted to develop a scale to assess the perceived credibility of CSR reports, one of CSR communication’s most important tools. The scale provides a novel operationalization of credibility using validity claims of Habermas’s ideal speech situation as subdimensions. The scale development process, carried out in five studies including a literature review, a Delphi study, and three validation studies applying confirmatory factor analysis, resulted in the 16-item Perceived Credibility (PERCRED) scale. The scale shows convergent, discriminant, concurrent, and nomological validity and is the first validated measure for analyzing credibility perceptions of CSR reports. PMID:29278260

  17. Measuring Credibility Perceptions in CSR Communication: A Scale Development to Test Readers' Perceived Credibility of CSR Reports.

    PubMed

    Lock, Irina; Seele, Peter

    2017-11-01

    Credibility is central to communication but often jeopardized by "credibility gaps." This is especially true for communication about corporate social responsibility (CSR). To date, no tool has been available to analyze stakeholders' credibility perceptions of CSR communication. This article presents a series of studies conducted to develop a scale to assess the perceived credibility of CSR reports, one of CSR communication's most important tools. The scale provides a novel operationalization of credibility using validity claims of Habermas's ideal speech situation as subdimensions. The scale development process, carried out in five studies including a literature review, a Delphi study, and three validation studies applying confirmatory factor analysis, resulted in the 16-item Perceived Credibility (PERCRED) scale. The scale shows convergent, discriminant, concurrent, and nomological validity and is the first validated measure for analyzing credibility perceptions of CSR reports.

  18. 26 CFR 1.815-3 - Shareholders surplus account.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ....815-3 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Distributions to Shareholders § 1.815-3 Shareholders surplus account. (a) In general. Every stock life insurance company subject to the tax imposed by section 802 shall establish and...

  19. Circuitry Linking the Csr and Stringent Response Global Regulatory Systems

    PubMed Central

    Edwards, Adrianne N.; Patterson-Fortin, Laura M.; Vakulskas, Christopher A.; Mercante, Jeffrey W.; Potrykus, Katarzyna; Vinella, Daniel; Camacho, Martha I.; Fields, Joshua A.; Thompson, Stuart A.; Georgellis, Dimitris; Cashel, Michael; Babitzke, Paul; Romeo, Tony

    2011-01-01

    Summary CsrA protein regulates important cellular processes by binding to target mRNAs and altering their translation and/or stability. In Escherichia coli, CsrA binds to sRNAs, CsrB and CsrC, which sequester CsrA and antagonize its activity. Here, mRNAs for relA, spoT and dksA of the stringent response system were found among 721 different transcripts that copurified with CsrA. Many of the transcripts that copurified with CsrA were previously determined to respond to ppGpp and/or DksA. We examined multiple regulatory interactions between the Csr and stringent response systems. Most importantly, DksA and ppGpp robustly activated csrB/C transcription (10-fold), while they modestly activated csrA expression. We propose that CsrA-mediated regulation is relieved during the stringent response. Gel shift assays confirmed high affinity binding of CsrA to relA mRNA leader and weaker interactions with dksA and spoT. Reporter fusions, qRT-PCR, and immunoblotting showed that CsrA repressed relA expression, and (p)ppGpp accumulation during stringent response was enhanced in a csrA mutant. CsrA had modest to negligible effects on dksA and spoT expression. Transcription of dksA was negatively autoregulated via a feedback loop that tended to mask CsrA effects. We propose that the Csr system fine-tunes the stringent response and discuss biological implications of the composite circuitry. PMID:21488981

  20. Effects of Core-Shell Rubber (CSR) Nanoparticles on the Cryogenic Fracture Toughness of CSR Modified Epoxy

    NASA Technical Reports Server (NTRS)

    Wang, Jun; Magee, Daniel; Schneider, Judy; Cannon, Seth

    2009-01-01

    This study investigated the effects of core-shell rubber (CSR) nanoparticles on the mechanical properties and fracture toughness of an epoxy resin at ambient and liquid nitrogen (LN2) temperatures. Varying amounts of Kane Ace(Registered TradeMark) MX130 and Kane Ace(Registered TradeMark) MX960 toughening agent were added to a commercially available EPON 862/Epikure W epoxy resin. Elastic modulus was calculated using quasi-static tensile data. Fracture toughness was evaluated by the resulting breaking energy measured in Charpy impact tests conducted on an instrumented drop tower. The size and distribution of the CSR nanoparticles were characterized using Transmission Electron Microscopy (TEM) and Small Angle X-ray Scattering (SAXS). Scanning Electron Microscopy (SEM) was used to study the fracture surface morphology. The addition of the CSR nanoparticles increased the breaking energy with negligible change in elastic modulus and ultimate tensile stress (UTS). At ambient temperature the breaking energy increased with increasing additions of the CSR nanoparticles up to 13.8wt%, while at LN2 temperatures, it reached a plateau at much lower CSR concentration.

  1. Circuitry linking the Csr and stringent response global regulatory systems.

    PubMed

    Edwards, Adrianne N; Patterson-Fortin, Laura M; Vakulskas, Christopher A; Mercante, Jeffrey W; Potrykus, Katarzyna; Vinella, Daniel; Camacho, Martha I; Fields, Joshua A; Thompson, Stuart A; Georgellis, Dimitris; Cashel, Michael; Babitzke, Paul; Romeo, Tony

    2011-06-01

    CsrA protein regulates important cellular processes by binding to target mRNAs and altering their translation and/or stability. In Escherichia coli, CsrA binds to sRNAs, CsrB and CsrC, which sequester CsrA and antagonize its activity. Here, mRNAs for relA, spoT and dksA of the stringent response system were found among 721 different transcripts that copurified with CsrA. Many of the transcripts that copurified with CsrA were previously determined to respond to ppGpp and/or DksA. We examined multiple regulatory interactions between the Csr and stringent response systems. Most importantly, DksA and ppGpp robustly activated csrB/C transcription (10-fold), while they modestly activated csrA expression. We propose that CsrA-mediated regulation is relieved during the stringent response. Gel shift assays confirmed high affinity binding of CsrA to relA mRNA leader and weaker interactions with dksA and spoT. Reporter fusions, qRT-PCR and immunoblotting showed that CsrA repressed relA expression, and (p)ppGpp accumulation during stringent response was enhanced in a csrA mutant. CsrA had modest to negligible effects on dksA and spoT expression. Transcription of dksA was negatively autoregulated via a feedback loop that tended to mask CsrA effects. We propose that the Csr system fine-tunes the stringent response and discuss biological implications of the composite circuitry. © Published 2011. This article is a US Government work and is in the public domain in the USA.

  2. 26 CFR 1.1254-4 - Special rules for S corporations and their shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shareholder's share of the fair market value and basis, and the shareholder's section 1254 costs, for each of... shareholders. 1.1254-4 Section 1.1254-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY....1254-4 Special rules for S corporations and their shareholders. (a) In general. This section provides...

  3. CsrA Represses Translation of sdiA, Which Encodes the N-Acylhomoserine-l-Lactone Receptor of Escherichia coli, by Binding Exclusively within the Coding Region of sdiA mRNA ▿ †

    PubMed Central

    Yakhnin, Helen; Baker, Carol S.; Berezin, Igor; Evangelista, Michael A.; Rassin, Alisa; Romeo, Tony; Babitzke, Paul

    2011-01-01

    The RNA binding protein CsrA is the central component of a conserved global regulatory system that activates or represses gene expression posttranscriptionally. In every known example of CsrA-mediated translational control, CsrA binds to the 5′ untranslated region of target transcripts, thereby repressing translation initiation and/or altering the stability of the RNA. Furthermore, with few exceptions, repression by CsrA involves binding directly to the Shine-Dalgarno sequence and blocking ribosome binding. sdiA encodes the quorum-sensing receptor for N-acyl-l-homoserine lactone in Escherichia coli. Because sdiA indirectly stimulates transcription of csrB, which encodes a small RNA (sRNA) antagonist of CsrA, we further explored the relationship between sdiA and the Csr system. Primer extension analysis revealed four putative transcription start sites within 85 nucleotides of the sdiA initiation codon. Potential σ70-dependent promoters were identified for each of these primer extension products. In addition, two CsrA binding sites were predicted in the initially translated region of sdiA. Expression of chromosomally integrated sdiA′-′lacZ translational fusions containing the entire promoter and CsrA binding site regions indicates that CsrA represses sdiA expression. The results from gel shift and footprint studies demonstrate that tight binding of CsrA requires both of these sites. Furthermore, the results from toeprint and in vitro translation experiments indicate that CsrA represses translation of sdiA by directly competing with 30S ribosomal subunit binding. Thus, this represents the first example of CsrA preventing translation by interacting solely within the coding region of an mRNA target. PMID:21908661

  4. A Study of Central Sterilization Room (CSR) Control and Organization at the Naval Regional Medical Center, Oakland, California.

    DTIC Science & Technology

    1979-08-01

    management and under overall supervicion of a supervisour nurse (08-9) in charge of CSR . Individual will have operational responsibility for CSR ...mD~ ; EL ::%~ rl- CgROCOPV RESOtUTIOI TEST CMMR NAUT ON AM OF SrAsfas-ua4 I C41 0 A STUDY OF CENTRAL STERILIZATION ROOM ( CSR )a CONTROL...MUEtsrbt niie PERORIN ONIATIO C OD IS. U3JECT TR S. MNITOIN ORAIZTO REPORT NUMBER S) inres NAEmpai On theORIN organisatioN an managemen ofC theBO CSR

  5. 26 CFR 1.883-4T - Qualified shareholder stock ownership test (temporary).

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Qualified shareholder stock ownership test... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Foreign Corporations § 1.883-4T Qualified shareholder stock...)(E) through (e)(1). (2) With respect to all qualified shareholders relied upon to satisfy the 50...

  6. Regulation of Bacterial Virulence by Csr (Rsm) Systems

    PubMed Central

    Vakulskas, Christopher A.; Potts, Anastasia H.; Babitzke, Paul; Ahmer, Brian M. M.

    2015-01-01

    SUMMARY Most bacterial pathogens have the remarkable ability to flourish in the external environment and in specialized host niches. This ability requires their metabolism, physiology, and virulence factors to be responsive to changes in their surroundings. It is no surprise that the underlying genetic circuitry that supports this adaptability is multilayered and exceedingly complex. Studies over the past 2 decades have established that the CsrA/RsmA proteins, global regulators of posttranscriptional gene expression, play important roles in the expression of virulence factors of numerous proteobacterial pathogens. To accomplish these tasks, CsrA binds to the 5′ untranslated and/or early coding regions of mRNAs and alters translation, mRNA turnover, and/or transcript elongation. CsrA activity is regulated by noncoding small RNAs (sRNAs) that contain multiple CsrA binding sites, which permit them to sequester multiple CsrA homodimers away from mRNA targets. Environmental cues sensed by two-component signal transduction systems and other regulatory factors govern the expression of the CsrA-binding sRNAs and, ultimately, the effects of CsrA on secretion systems, surface molecules and biofilm formation, quorum sensing, motility, pigmentation, siderophore production, and phagocytic avoidance. This review presents the workings of the Csr system, the paradigm shift that it generated for understanding posttranscriptional regulation, and its roles in virulence networks of animal and plant pathogens. PMID:25833324

  7. Spontaneous Speech Collection for the CSR Corpus

    DTIC Science & Technology

    1992-01-01

    Menlo Park, California 94025 1. ABSTRACT As part of a pilot data collection for DARPA’s Continuous Speech Recognition ( CSR ) speech corpus, SRI...International experi- mented with the collection of spontaneous speeoh material. The bulk of the CSR pilot data was read versions of news articles from...variable. 2. INTRODUCTION The CSR (Continuous Speech Recognition) Corpus collec- tion can be considered the successor to the Resource Man- agemen t

  8. Regulation of bacterial virulence by Csr (Rsm) systems.

    PubMed

    Vakulskas, Christopher A; Potts, Anastasia H; Babitzke, Paul; Ahmer, Brian M M; Romeo, Tony

    2015-06-01

    Most bacterial pathogens have the remarkable ability to flourish in the external environment and in specialized host niches. This ability requires their metabolism, physiology, and virulence factors to be responsive to changes in their surroundings. It is no surprise that the underlying genetic circuitry that supports this adaptability is multilayered and exceedingly complex. Studies over the past 2 decades have established that the CsrA/RsmA proteins, global regulators of posttranscriptional gene expression, play important roles in the expression of virulence factors of numerous proteobacterial pathogens. To accomplish these tasks, CsrA binds to the 5' untranslated and/or early coding regions of mRNAs and alters translation, mRNA turnover, and/or transcript elongation. CsrA activity is regulated by noncoding small RNAs (sRNAs) that contain multiple CsrA binding sites, which permit them to sequester multiple CsrA homodimers away from mRNA targets. Environmental cues sensed by two-component signal transduction systems and other regulatory factors govern the expression of the CsrA-binding sRNAs and, ultimately, the effects of CsrA on secretion systems, surface molecules and biofilm formation, quorum sensing, motility, pigmentation, siderophore production, and phagocytic avoidance. This review presents the workings of the Csr system, the paradigm shift that it generated for understanding posttranscriptional regulation, and its roles in virulence networks of animal and plant pathogens. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  9. Impaired class switch recombination (CSR) in Waldenstrom macroglobulinemia (WM) despite apparently normal CSR machinery.

    PubMed

    Kriangkum, Jitra; Taylor, Brian J; Strachan, Erin; Mant, Michael J; Reiman, Tony; Belch, Andrew R; Pilarski, Linda M

    2006-04-01

    Analysis of clonotypic isotype class switching (CSR) in Waldenström macroglobulinemia (WM) and IgM monoclonal gammopathy of undetermined significance (MGUS) reveals a normal initial phase of B-cell activation as determined by constitutive and inducible expression of activation-induced cytidine deaminase (AID). Switch mu (Smu) analysis shows that large deletions are not common in WM or IgM MGUS. In CD40L/IL-4-stimulated WM cultures from 2 patients, we observed clonotypic IgG exhibiting intraclonal homogeneity associated with multiple hybrid Smu/Sgamma junctions. This suggests CSR had occurred within WM cells. Nevertheless, the estimated IgG/IgM-cell frequency was relatively low (1/1600 cells). Thus, for the majority of WM B cells, CSR does not occur even when stimulated in vitro, suggesting that the WM cell is constitutively unable to or being prevented from carrying out CSR. In contrast to WM, the majority of IgM MGUS clones exhibit intraclonal heterogeneity of IgH VDJ. Furthermore, most IgM MGUS accumulate more mutations in the upstream Smu region than do WM, making them unlikely WM progenitors. These observations suggest that switch sequence analysis may identify the subset of patients with IgM MGUS who are at risk of progression to WM.

  10. CSR-1 Slices a Balance.

    PubMed

    Yu, Ruby; Moazed, Danesh

    2016-04-07

    CSR-1 is a germline-expressed C. elegans Argonaute protein essential for viability. In this issue of Cell, Gerson-Gurwitz et al. now demonstrate a role for CSR-1 and its slicer activity in downregulating the levels of maternally deposited mRNAs to fine-tune the expression of proteins with critical roles in embryonic cell divisions. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Business Students' Perceptions of Corporate Social Responsibility

    ERIC Educational Resources Information Center

    Fitzpatrick, Julie

    2013-01-01

    Corporate social responsibility (CSR) is a key element of today's Business school curricula. Proponents of CSR have argued that a business has an obligation to balance the interests of its many stakeholders. Critics of CSR, however, have argued that a business has an obligation only to its owners--its shareholders. In this paper I examined the…

  12. A direct link between the global regulator PhoP and the Csr regulon in Y. pseudotuberculosis through the small regulatory RNA CsrC.

    PubMed

    Nuss, Aaron M; Schuster, Franziska; Kathrin Heroven, Ann; Heine, Wiebke; Pisano, Fabio; Dersch, Petra

    2014-01-01

    In this study we investigated the influence of the global response regulator PhoP on the complex regulatory cascade controlling expression of early stage virulence genes of Yersinia pseudotuberculosis via the virulence regulator RovA. Our analysis revealed the following novel features: (1) PhoP activates expression of the CsrC RNA in Y. pseudotuberculosis, leading to activation of RovA synthesis through the CsrABC-RovM cascade, (2) activation of csrC transcription is direct and PhoP is shown to bind to two separate PhoP box-like sites, (3) PhoP-mediated activation results in transcription from two different promoters closely downstream of the PhoP binding sites, leading to two distinct CsrC RNAs, and (4) the stability of the CsrC RNAs differs significantly between the Y. pseudotuberculosis strains YPIII and IP32953 due to a 20 nucleotides insertion in CsrC(IP32953), which renders the transcript more susceptible to degradation. In summary, our study showed that PhoP-mediated influence on the regulatory cascade controlling the Csr system and RovA in Y. pseudotuberculosis varies within the species, suggesting that the Csr system is a focal point to readjust and adapt the genus to different hosts and reservoirs.

  13. Telling the Investment Story: A Narrative Analysis of Shareholder Reports.

    ERIC Educational Resources Information Center

    Jameson, Daphne A.

    2000-01-01

    Analyzes shareholder reports of equity mutual funds whose total returns were high in absolute terms, but low in relative terms. Reveals that mixed-return shareholder reports use a nonlinear hyperstructure, dramatize ideas through contrasting narrators, embed a variety of subgenres, and complement verbal with visual discourse in order to make…

  14. 76 FR 54814 - Proposed Collection; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-02

    ...) under the Investment Company Act of 1940 (15 U.S.C. 80a-1 et seq.) (the ``Investment Company Act'') requires a registered investment company (``fund'') to (1) File a report with the Commission on Form N-CSR... be transmitted to shareholders under rule 30e-1 under the Investment Company Act, and (2) file with...

  15. Circuitry Linking the Catabolite Repression and Csr Global Regulatory Systems of Escherichia coli.

    PubMed

    Pannuri, Archana; Vakulskas, Christopher A; Zere, Tesfalem; McGibbon, Louise C; Edwards, Adrianne N; Georgellis, Dimitris; Babitzke, Paul; Romeo, Tony

    2016-11-01

    Cyclic AMP (cAMP) and the cAMP receptor protein (cAMP-CRP) and CsrA are the principal regulators of the catabolite repression and carbon storage global regulatory systems, respectively. cAMP-CRP controls the transcription of genes for carbohydrate metabolism and other processes in response to carbon nutritional status, while CsrA binds to diverse mRNAs and regulates translation, RNA stability, and/or transcription elongation. CsrA also binds to the regulatory small RNAs (sRNAs) CsrB and CsrC, which antagonize its activity. The BarA-UvrY two-component signal transduction system (TCS) directly activates csrB and csrC (csrB/C) transcription, while CsrA does so indirectly. We show that cAMP-CRP inhibits csrB/C transcription without negatively regulating phosphorylated UvrY (P-UvrY) or CsrA levels. A crp deletion caused an elevation in CsrB/C levels in the stationary phase of growth and increased the expression of csrB-lacZ and csrC-lacZ transcriptional fusions, although modest stimulation of CsrB/C turnover by the crp deletion partially masked the former effects. DNase I footprinting and other studies demonstrated that cAMP-CRP bound specifically to three sites located upstream from the csrC promoter, two of which overlapped the P-UvrY binding site. These two proteins competed for binding at the overlapping sites. In vitro transcription-translation experiments confirmed direct repression of csrC-lacZ expression by cAMP-CRP. In contrast, cAMP-CRP effects on csrB transcription may be mediated indirectly, as it bound nonspecifically to csrB DNA. In the reciprocal direction, CsrA bound to crp mRNA with high affinity and specificity and yet exhibited only modest, conditional effects on expression. Our findings are incorporated into an emerging model for the response of Csr circuitry to carbon nutritional status. Csr (Rsm) noncoding small RNAs (sRNAs) CsrB and CsrC of Escherichia coli use molecular mimicry to sequester the RNA binding protein CsrA (RsmA) away from lower

  16. Circuitry Linking the Catabolite Repression and Csr Global Regulatory Systems of Escherichia coli

    PubMed Central

    Pannuri, Archana; Vakulskas, Christopher A.; Zere, Tesfalem; McGibbon, Louise C.; Edwards, Adrianne N.; Georgellis, Dimitris; Babitzke, Paul

    2016-01-01

    ABSTRACT Cyclic AMP (cAMP) and the cAMP receptor protein (cAMP-CRP) and CsrA are the principal regulators of the catabolite repression and carbon storage global regulatory systems, respectively. cAMP-CRP controls the transcription of genes for carbohydrate metabolism and other processes in response to carbon nutritional status, while CsrA binds to diverse mRNAs and regulates translation, RNA stability, and/or transcription elongation. CsrA also binds to the regulatory small RNAs (sRNAs) CsrB and CsrC, which antagonize its activity. The BarA-UvrY two-component signal transduction system (TCS) directly activates csrB and csrC (csrB/C) transcription, while CsrA does so indirectly. We show that cAMP-CRP inhibits csrB/C transcription without negatively regulating phosphorylated UvrY (P-UvrY) or CsrA levels. A crp deletion caused an elevation in CsrB/C levels in the stationary phase of growth and increased the expression of csrB-lacZ and csrC-lacZ transcriptional fusions, although modest stimulation of CsrB/C turnover by the crp deletion partially masked the former effects. DNase I footprinting and other studies demonstrated that cAMP-CRP bound specifically to three sites located upstream from the csrC promoter, two of which overlapped the P-UvrY binding site. These two proteins competed for binding at the overlapping sites. In vitro transcription-translation experiments confirmed direct repression of csrC-lacZ expression by cAMP-CRP. In contrast, cAMP-CRP effects on csrB transcription may be mediated indirectly, as it bound nonspecifically to csrB DNA. In the reciprocal direction, CsrA bound to crp mRNA with high affinity and specificity and yet exhibited only modest, conditional effects on expression. Our findings are incorporated into an emerging model for the response of Csr circuitry to carbon nutritional status. IMPORTANCE Csr (Rsm) noncoding small RNAs (sRNAs) CsrB and CsrC of Escherichia coli use molecular mimicry to sequester the RNA binding protein CsrA (Rsm

  17. Implementation: Measuring and Explaining the Fidelity of CSR Implementation

    ERIC Educational Resources Information Center

    Kurki, Anja; Boyle, Andrea; Aladjem, Daniel K.

    2006-01-01

    Comprehensive school reform (CSR) is only as effective as its implementation. By using data collected for the National Longitudinal Evaluation of Comprehensive School Reform (NLECSR), this article explores the factors that predict CSR model implementation and the ways that CSR model implementation varies. We found little difference in the fidelity…

  18. When Corporate Social Responsibility (CSR) Meets Organizational Psychology: New Frontiers in Micro-CSR Research, and Fulfilling a Quid Pro Quo through Multilevel Insights.

    PubMed

    Jones, David A; Willness, Chelsea R; Glavas, Ante

    2017-01-01

    Researchers, corporate leaders, and other stakeholders have shown increasing interest in Corporate Social Responsibility (CSR)-a company's discretionary actions and policies that appear to advance societal well-being beyond its immediate financial interests and legal requirements. Spanning decades of research activity, the scholarly literature on CSR has been dominated by meso- and macro-level perspectives, such as studies within corporate strategy that examine relationships between firm-level indicators of social/environmental performance and corporate financial performance. In recent years, however, there has been an explosion of micro-oriented CSR research conducted at the individual level of analysis, especially with respect to studies on how and why job seekers and employees perceive and react to CSR practices. This micro-level focus is reflected in 12 articles published as a Research Topic collection in Frontiers in Psychology (Organizational Psychology Specialty Section) titled "CSR and organizational psychology: Quid pro quo." In the present article, the authors summarize and integrate findings from these Research Topic articles. After describing some of the "new frontiers" these articles explore and create, the authors strive to fulfill a "quid pro quo" with some of the meso- and macro-oriented CSR literatures that paved the way for micro-CSR research. Specifically, the authors draw on insights from the Research Topic articles to inform a multilevel model that offers multiple illustrations of how micro-level processes among individual stakeholders can explain variability in meso (firm)-level relationships between CSR practices and corporate performance. The authors also explore an important implication of these multilevel processes for macro-level societal impact.

  19. Translational Repression of NhaR, a Novel Pathway for Multi-Tier Regulation of Biofilm Circuitry by CsrA

    PubMed Central

    Pannuri, Archana; Yakhnin, Helen; Vakulskas, Christopher A.; Edwards, Adrianne N.; Babitzke, Paul

    2012-01-01

    The RNA binding protein CsrA (RsmA) represses biofilm formation in several proteobacterial species. In Escherichia coli, it represses the production of the polysaccharide adhesin poly-β-1,6-N-acetyl-d-glucosamine (PGA) by binding to the pgaABCD mRNA leader, inhibiting pgaA translation, and destabilizing this transcript. In addition, CsrA represses genes responsible for the synthesis of cyclic di-GMP, an activator of PGA production. Here we determined that CsrA also represses NhaR, a LysR-type transcriptional regulator which responds to elevated [Na+] and alkaline pH and activates the transcription of the pgaABCD operon. Gel shift studies revealed that CsrA binds at two sites in the 5′ untranslated segment of nhaR, one of which overlaps the Shine-Dalgarno sequence. An epitope-tagged NhaR protein, expressed from the nhaR chromosomal locus, and an nhaR posttranscriptional reporter fusion (PlacUV5-nhaR′-′lacZ) both showed robust repression by CsrA. Northern blotting revealed a complex transcription pattern for the nhaAR locus. Nevertheless, CsrA did not repress nhaR mRNA levels. Toeprinting assays showed that CsrA competes effectively with the ribosome for binding to the translation initiation region of nhaR. Together, these findings indicate that CsrA blocks nhaR translation. Epistasis studies with a pgaA-lacZ transcriptional fusion confirmed a model in which CsrA indirectly represses pgaABCD transcription via NhaR. We conclude that CsrA regulates the horizontally acquired pgaABCD operon and PGA biosynthesis at multiple levels. Furthermore, nhaR repression exemplifies an expanding role for CsrA as a global regulator of stress response systems. PMID:22037401

  20. When Corporate Social Responsibility (CSR) Meets Organizational Psychology: New Frontiers in Micro-CSR Research, and Fulfilling a Quid Pro Quo through Multilevel Insights

    PubMed Central

    Jones, David A.; Willness, Chelsea R.; Glavas, Ante

    2017-01-01

    Researchers, corporate leaders, and other stakeholders have shown increasing interest in Corporate Social Responsibility (CSR)—a company’s discretionary actions and policies that appear to advance societal well-being beyond its immediate financial interests and legal requirements. Spanning decades of research activity, the scholarly literature on CSR has been dominated by meso- and macro-level perspectives, such as studies within corporate strategy that examine relationships between firm-level indicators of social/environmental performance and corporate financial performance. In recent years, however, there has been an explosion of micro-oriented CSR research conducted at the individual level of analysis, especially with respect to studies on how and why job seekers and employees perceive and react to CSR practices. This micro-level focus is reflected in 12 articles published as a Research Topic collection in Frontiers in Psychology (Organizational Psychology Specialty Section) titled “CSR and organizational psychology: Quid pro quo.” In the present article, the authors summarize and integrate findings from these Research Topic articles. After describing some of the “new frontiers” these articles explore and create, the authors strive to fulfill a “quid pro quo” with some of the meso- and macro-oriented CSR literatures that paved the way for micro-CSR research. Specifically, the authors draw on insights from the Research Topic articles to inform a multilevel model that offers multiple illustrations of how micro-level processes among individual stakeholders can explain variability in meso (firm)-level relationships between CSR practices and corporate performance. The authors also explore an important implication of these multilevel processes for macro-level societal impact. PMID:28439247

  1. Duties to stakeholders amidst pressures from shareholders: lessons from an advisory panel on transplant policy.

    PubMed

    Mongoven, Ann M

    2003-08-01

    The distinction between stakeholders and shareholders frequently employed in business ethics can illuminate challenges faced by a bioethics advisory panel. I use the distinction to reflect back on the work of an advisory panel on which I served, a panel on US transplant policy. The panel hearings were akin to a shareholders' meeting, with many stakeholders absent. In addition to 'hearing out' the shareholders who were present, the panel had duties to absent stakeholders to insure their interests were included in public discussion. While panel efforts to include stakeholder perspectives rightfully framed its report, such duties should have framed its operating procedures more robustly. The stakeholder/shareholder distinction also offers a critical prism on the actual evolution of organ allocation policy, which the panel failed to influence. Current policy embodies a compromise among shareholders that obscures major stakeholder interests. This results in under-attention to likely medical benefit of transplant, compared to other allocation criteria. Recognition of duties to stakeholders amidst pressures of shareholders complicates the notion of 'consensus' for an advisory panel. Consensus framed on terms defined only by shareholders, not stakeholders, may be an inadequate measure of public interest.

  2. 26 CFR 1.853-1 - Foreign tax credit allowed to shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Foreign tax credit allowed to shareholders. 1....853-1 Foreign tax credit allowed to shareholders. (a) In general. Under section 853, a regulated... paid by it pursuant to any income tax convention, as either a credit (under section 901) or as a...

  3. 12 CFR 552.6 - Shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... shareholders of the association for the election of directors and for the transaction of any other business of... directors may perform such acts as required by paragraphs (a) and (b) of Rule 14a-7 of the General Rules and... law or the charter. Directors, however, are elected by a plurality of the votes cast at an election of...

  4. 26 CFR 1.995-1 - Taxation of DISC income to shareholders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 10 2011-04-01 2011-04-01 false Taxation of DISC income to shareholders. 1.995... Taxation of DISC income to shareholders. (a) In general. (1) Under § 1.991-1(a), a corporation which is a... DISC, are subject to taxation on the earnings and profits of the DISC in accordance with the provisions...

  5. 78 FR 79650 - Definitions and Reporting Requirements for Shareholders of Passive Foreign Investment Companies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ...In the Rules and Regulations section of this issue of the Federal Register, the IRS and the Department of the Treasury (Treasury Department) are issuing temporary regulations that provide guidance on determining the ownership of a passive foreign investment company (PFIC), the annual filing requirements for shareholders of PFICs, and an exclusion from certain filing requirement for shareholders that constructively own interests in certain foreign corporations. The temporary regulations primarily affect shareholders of PFICs that do not currently file Form 8621, ``Information Return by a Shareholder of a Passive Foreign Investment Company or Qualified Electing Fund'', with respect to their PFIC interests. The temporary regulations also affect certain shareholders that rely on a constructive ownership exception to the requirement to file Form 5471, ``Information Return of U.S. Persons with Respect to Certain Foreign Corporations.'' The text of those temporary regulations published in this issue of the Federal Register also serves as the text of these proposed regulations.

  6. Does Practicing CSR Makes Consumers Like Your Shop More? Consumer-Retailer Love Mediates CSR and Behavioral Intentions.

    PubMed

    Ho, Ching-Wei

    2017-12-12

    This research paper was designed to examine the influence of corporate social responsibility (CSR) associations and environmental concerns on consumer-retailer love and attitude toward the retailer, as well as the subsequent effects on consumer behavioral intentions regarding the retailer, such as repeat patronage intention and willingness to pay a premium price for products offered by the retailer. In this study, a questionnaire survey was conducted on consumers for the purpose of investigating five proposed hypotheses. This research applied partial least squares (PLS) to exam the hypotheses and analyze the data. The findings of this research indicated that CSR association and environmental concern both have positive effects on consumer-retailer love and attitude toward the retailer. Also, the results showed that consumer-retailer love has a significantly positive effect on consumer attitude towards the retailer. This paper establishes that consumer-retailer love and attitude toward a retailer are main mediators of the relationship between CSR associations, environmental concern, and consumer behavioral intentions.

  7. Does Practicing CSR Makes Consumers Like Your Shop More? Consumer-Retailer Love Mediates CSR and Behavioral Intentions

    PubMed Central

    Ho, Ching-Wei

    2017-01-01

    This research paper was designed to examine the influence of corporate social responsibility (CSR) associations and environmental concerns on consumer-retailer love and attitude toward the retailer, as well as the subsequent effects on consumer behavioral intentions regarding the retailer, such as repeat patronage intention and willingness to pay a premium price for products offered by the retailer. In this study, a questionnaire survey was conducted on consumers for the purpose of investigating five proposed hypotheses. This research applied partial least squares (PLS) to exam the hypotheses and analyze the data. The findings of this research indicated that CSR association and environmental concern both have positive effects on consumer-retailer love and attitude toward the retailer. Also, the results showed that consumer-retailer love has a significantly positive effect on consumer attitude towards the retailer. This paper establishes that consumer-retailer love and attitude toward a retailer are main mediators of the relationship between CSR associations, environmental concern, and consumer behavioral intentions. PMID:29231873

  8. Circuitry linking the global Csr and σE-dependent cell envelope stress response systems.

    PubMed

    Yakhnin, Helen; Aichele, Robert; Ades, Sarah E; Romeo, Tony; Babitzke, Paul

    2017-09-18

    CsrA of Escherichia coli is an RNA-binding protein that globally regulates a wide variety of cellular processes and behaviors including carbon metabolism, motility, biofilm formation, and the stringent response. CsrB and CsrC are sRNAs that sequester CsrA, thereby preventing CsrA-mRNA interaction. RpoE (σ E ) is the extracytoplasmic stress response sigma factor of E. coli Previous RNA-seq studies identified rpoE mRNA as a CsrA target. Here we explored the regulation of rpoE by CsrA and found that CsrA represses rpoE translation. Gel mobility shift, footprint and toeprint studies identified three CsrA binding sites in the rpoE leader transcript, one of which overlaps the rpoE Shine-Dalgarno (SD) sequence, while another overlaps the rpoE translation initiation codon. Coupled in vitro transcription-translation experiments showed that CsrA represses rpoE translation by binding to these sites. We further demonstrate that σ E indirectly activates transcription of csrB and csrC , leading to increased sequestration of CsrA such that repression of rpoE by CsrA is reduced. We propose that the Csr system fine-tunes the σ E -dependent cell envelope stress response. We also identified a 51 amino acid coding sequence whose stop codon overlaps the rpoE start codon, and demonstrate that rpoE is translationally coupled with this upstream open reading frame (ORF51). Loss of coupling reduces rpoE translation by more than 50%. Identification of a translationally coupled ORF upstream of rpoE suggests that this previously unannotated protein may participate in the cell envelope stress response. In keeping with existing nomenclature, we name ORF51 as rseD , resulting in an operon arrangement of rseD-rpoE-rseA-rseB-rseC IMPORTANCE CsrA posttranscriptionally represses genes required for bacterial stress responses, including the stringent response, catabolite repression, and the RpoS (σ S )-mediated general stress response. We show that CsrA represses translation of rpoE , encoding the

  9. The global regulatory system Csr senses glucose through the phosphoenolpyruvate: carbohydrate phosphotransferase system.

    PubMed

    Pérez-Morales, Deyanira; Bustamante, Víctor H

    2016-02-01

    A novel connection between two regulatory systems controlling crucial biological processes in bacteria, the carbon storage regulator (Csr) system and the glucose-specific phosphotransferase system (PTS), is reported by Leng et al. in this issue. This involves the interaction of unphosphorylated EIIA(Glc), a component of the glucose-specific PTS, with the CsrD protein, which accelerates the decay of the CsrB and CsrC small RNAs via RNase E in Escherichia coli. As unphosphorylated EIIA(G) (lc) is generated in the presence of glucose, the PTS thus acts as a sensor of glucose for the Csr system. Interestingly, another pathway can operate for communication between the Csr system and the glucose-specific PTS. The absence of glucose generates phosphorylated EIIA(Glc) , which activates the enzyme adenylate cyclase to produce cyclic adenosine monophosphate (cAMP) that, in turn, binds to the regulator cAMP receptor protein (CRP). Leng et al. show that the complex cAMP-CRP modestly reduces CsrB decay independently of CsrD. On the other hand, a previous study indicates that the complex cAMP-CRP positively regulates the transcription of CsrB and CsrC in Salmonella enterica. Therefore, EIIA(G) (lc) could work as a molecular switch that regulates the activity of the Csr system, in response to its phosphorylation state determined by the presence or absence of glucose, in order to control gene expression. © 2015 John Wiley & Sons Ltd.

  10. Posttranscriptional regulation on a global scale: Form and function of Csr/Rsm systems

    PubMed Central

    Romeo, Tony; Vakulskas, Christopher A.; Babitzke, Paul

    2012-01-01

    Summary Originally described as a repressor of gene expression in the stationary phase of growth, CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation, motility, virulence circuitry of pathogens, quorum sensing, and stress response systems by binding to conserved sequences in its target mRNAs and altering their translation and/or turnover. While the binding of CsrA to RNA is understood at an atomic level, new mechanisms of gene activation and repression by this protein are still emerging. In the γ-proteobacteria, small noncoding RNAs (sRNAs) use molecular mimicry to sequester multiple CsrA dimers away from mRNA. In contrast, the FliW protein of Bacillus subtilis inhibits CsrA activity by binding to this protein, thereby establishing a checkpoint in flagellum morphogenesis. Turnover of CsrB and CsrC sRNAs in Escherichia coli requires a specificity protein of the GGDEF-EAL domain superfamily, CsrD, in addition to the housekeeping nucleases RNase E and PNPase. The Csr system of E. coli contains extensive autoregulatory circuitry, which governs the expression and activity of CsrA. Interaction of the Csr system with transcriptional regulatory networks results in a variety of complex response patterns. This minireview will highlight basic principles and new insights into the workings of these complex eubacterial regulatory systems. PMID:22672726

  11. 25 CFR 111.4 - Election of shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PAYMENTS § 111.4 Election of shareholders. An Indian holding equal rights in two or more tribes can share... enrolled and to relinquish in writing his claims to payments to the other. In the case of a minor the...

  12. The effect of adaptive servo ventilation (ASV) on objective and subjective outcomes in Cheyne-Stokes respiration (CSR) with central sleep apnea (CSA) in heart failure (HF): A systematic review.

    PubMed

    Yang, Hyunju; Sawyer, Amy M

    2016-01-01

    To summarize the current evidence for adaptive servo ventilation (ASV) in Cheyne-Stokes respiration (CSR) with central sleep apnea (CSA) in heart failure (HF) and advance a research agenda and clinical considerations for ASV-treated CSR-CSA in HF. CSR-CSA in HF is associated with higher overall mortality, worse outcomes and lower quality of life (QOL) than HF without CSR-CSA. Five databases were searched using key words (n = 234). Randomized controlled trials assessed objective sleep quality, cardiac, and self-reported outcomes in adults (≥18 years) with HF (n = 10). ASV has a beneficial effect on the reduction of central sleep apnea in adult patients with CSR-CSA in HF, but it is not be superior to CPAP, bilevel PPV, or supplemental oxygen in terms of sleep quality defined by polysomnography, cardiovascular outcomes, subjective daytime sleepiness, and quality of life. ASV is not recommended for CSR-CSA in HF. It is important to continue to refer HF patients for sleep evaluation to clearly discern OSA from CSR-CSA. Symptom management research, inclusive of objective and subjective outcomes, in CSR-CSA in HF adults is needed. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. 76 FR 71248 - Animal Food Labeling; Declaration of Certifiable Color Additives

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-17

    .... FDA-2009-N-0025] Animal Food Labeling; Declaration of Certifiable Color Additives AGENCY: Food and... amending its regulations regarding the declaration of certified color additives on the labels of animal... common or usual names of all color additives required to be certified by FDA. An additional purpose of...

  14. 5 CFR 847.503 - Transfers from the CSR Fund.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Transfers from the CSR Fund. 847.503 Section 847.503 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE... from the CSR Fund. For elections of NAFI retirement system coverage under § 847.441, the amount under...

  15. Post-transcriptional regulation on a global scale: form and function of Csr/Rsm systems.

    PubMed

    Romeo, Tony; Vakulskas, Christopher A; Babitzke, Paul

    2013-02-01

    Originally described as a repressor of gene expression in the stationary phase of growth, CsrA (RsmA) regulates primary and secondary metabolic pathways, biofilm formation, motility, virulence circuitry of pathogens, quorum sensing and stress response systems by binding to conserved sequences in its target mRNAs and altering their translation and/or turnover. While the binding of CsrA to RNA is understood at an atomic level, new mechanisms of gene activation and repression by this protein are still emerging. In the γ-proteobacteria, small non-coding RNAs (sRNAs) use molecular mimicry to sequester multiple CsrA dimers away from mRNA. In contrast, the FliW protein of Bacillus subtilis inhibits CsrA activity by binding to this protein, thereby establishing a checkpoint in flagellum morphogenesis. Turnover of CsrB and CsrC sRNAs in Escherichia coli requires a specificity protein of the GGDEF-EAL domain superfamily, CsrD, in addition to the housekeeping nucleases RNase E and PNPase. The Csr system of E. coli contains extensive autoregulatory circuitry, which governs the expression and activity of CsrA. Interaction of the Csr system with transcriptional regulatory networks results in a variety of complex response patterns. This minireview will highlight basic principles and new insights into the workings of these complex eubacterial regulatory systems. © 2012 Society for Applied Microbiology and Blackwell Publishing Ltd.

  16. 76 FR 58100 - Facilitating Shareholder Director Nominations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-20

    ...: Securities and Exchange Commission. ACTION: Final rule; notice of effective date. SUMMARY: This release provides notice of the effective date of the amendment to Exchange Act Rule 14a-8, the shareholder proposal rule, which will require companies to include in their proxy materials, under certain circumstances...

  17. 5 CFR 847.502 - Transfers to the CSR Fund.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Transfers to the CSR Fund. 847.502 Section 847.502 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE... to the CSR Fund. For elections of CSRS or FERS coverage under § 847.411 or FERS coverage and service...

  18. The Limits of Corporate Social Responsibility: Techniques of Neutralization, Stakeholder Management and Political CSR.

    PubMed

    Fooks, Gary; Gilmore, Anna; Collin, Jeff; Holden, Chris; Lee, Kelley

    2013-01-01

    Since scholarly interest in corporate social responsibility (CSR) has primarily focused on the synergies between social and economic performance, our understanding of how (and the conditions under which) companies use CSR to produce policy outcomes that work against public welfare has remained comparatively under-developed. In particular, little is known about how corporate decision-makers privately reconcile the conflicts between public and private interests, even though this is likely to be relevant to understanding the limitations of CSR as a means of aligning business activity with the broader public interest. This study addresses this issue using internal tobacco industry documents to explore British-American Tobacco's (BAT) thinking on CSR and its effects on the company's CSR Programme. The article presents a three-stage model of CSR development, based on Sykes and Matza's theory of techniques of neutralization, which links together: how BAT managers made sense of the company's declining political authority in the mid-1990s; how they subsequently justified the use of CSR as a tool of stakeholder management aimed at diffusing the political impact of public health advocates by breaking up political constituencies working towards evidence-based tobacco regulation; and how CSR works ideologically to shape stakeholders' perceptions of the relative merits of competing approaches to tobacco control. Our analysis has three implications for research and practice. First, it underlines the importance of approaching corporate managers' public comments on CSR critically and situating them in their economic, political and historical contexts. Second, it illustrates the importance of focusing on the political aims and effects of CSR. Third, by showing how CSR practices are used to stymie evidence-based government regulation, the article underlines the importance of highlighting and developing matrices to assess the negative social impacts of CSR.

  19. Molecular basis for the wide range of affinity found in Csr/Rsm protein-RNA recognition.

    PubMed

    Duss, Olivier; Michel, Erich; Diarra dit Konté, Nana; Schubert, Mario; Allain, Frédéric H-T

    2014-04-01

    The carbon storage regulator/regulator of secondary metabolism (Csr/Rsm) type of small non-coding RNAs (sRNAs) is widespread throughout bacteria and acts by sequestering the global translation repressor protein CsrA/RsmE from the ribosome binding site of a subset of mRNAs. Although we have previously described the molecular basis of a high affinity RNA target bound to RsmE, it remains unknown how other lower affinity targets are recognized by the same protein. Here, we have determined the nuclear magnetic resonance solution structures of five separate GGA binding motifs of the sRNA RsmZ of Pseudomonas fluorescens in complex with RsmE. The structures explain how the variation of sequence and structural context of the GGA binding motifs modulate the binding affinity for RsmE by five orders of magnitude (∼10 nM to ∼3 mM, Kd). Furthermore, we see that conformational adaptation of protein side-chains and RNA enable recognition of different RNA sequences by the same protein contributing to binding affinity without conferring specificity. Overall, our findings illustrate how the variability in the Csr/Rsm protein-RNA recognition allows a fine-tuning of the competition between mRNAs and sRNAs for the CsrA/RsmE protein.

  20. Entrance and Exit CSR Impedance for Non-Ultrarelativistic Beam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Rui; Tsai, Cheng Ying

    2017-05-01

    For a high-brightness electron beam being transported through beamlines involving bending systems, the coherent synchrotron radiation (CSR) and longitudinal space charge (LSC) interaction could often cause microbunching instability. The semi-analytical Vlasov solver for microbunching gain* depends on the impedances for the relevant collective effects. The existing results for CSR impedances are usually obtained for the ultrarelativistic limit. To extend the microbunching analysis to cases of low energies, such as the case of an ERL merger, or to density modulations at extremely small wavelength, it is necessary to extend the impedance analysis to the non-ultrarelativistic regime. In this study, we presentmore » the impedance analysis for the transient CSR interaction in the non-ultrarelativistic regime, for transients including both entrance to and exit from a magnetic dipole. These impedance results will be compared to their ultra-relativistic counterparts**, and the corresponding wakefield obtained from the impedance for low-energy beams will be compared with the existing results of transient CSR wakefield for general beam energies***.« less

  1. The Csr system regulates genome-wide mRNA stability and transcription and thus gene expression in Escherichia coli.

    PubMed

    Esquerré, Thomas; Bouvier, Marie; Turlan, Catherine; Carpousis, Agamemnon J; Girbal, Laurence; Cocaign-Bousquet, Muriel

    2016-04-26

    Bacterial adaptation requires large-scale regulation of gene expression. We have performed a genome-wide analysis of the Csr system, which regulates many important cellular functions. The Csr system is involved in post-transcriptional regulation, but a role in transcriptional regulation has also been suggested. Two proteins, an RNA-binding protein CsrA and an atypical signaling protein CsrD, participate in the Csr system. Genome-wide transcript stabilities and levels were compared in wildtype E. coli (MG1655) and isogenic mutant strains deficient in CsrA or CsrD activity demonstrating for the first time that CsrA and CsrD are global negative and positive regulators of transcription, respectively. The role of CsrA in transcription regulation may be indirect due to the 4.6-fold increase in csrD mRNA concentration in the CsrA deficient strain. Transcriptional action of CsrA and CsrD on a few genes was validated by transcriptional fusions. In addition to an effect on transcription, CsrA stabilizes thousands of mRNAs. This is the first demonstration that CsrA is a global positive regulator of mRNA stability. For one hundred genes, we predict that direct control of mRNA stability by CsrA might contribute to metabolic adaptation by regulating expression of genes involved in carbon metabolism and transport independently of transcriptional regulation.

  2. Comparative functional characterization of the CSR-1 22G-RNA pathway in Caenorhabditis nematodes

    PubMed Central

    Tu, Shikui; Wu, Monica Z.; Wang, Jie; Cutter, Asher D.; Weng, Zhiping; Claycomb, Julie M.

    2015-01-01

    As a champion of small RNA research for two decades, Caenorhabditis elegans has revealed the essential Argonaute CSR-1 to play key nuclear roles in modulating chromatin, chromosome segregation and germline gene expression via 22G-small RNAs. Despite CSR-1 being preserved among diverse nematodes, the conservation and divergence in function of the targets of small RNA pathways remains poorly resolved. Here we apply comparative functional genomic analysis between C. elegans and Caenorhabditis briggsae to characterize the CSR-1 pathway, its targets and their evolution. C. briggsae CSR-1-associated small RNAs that we identified by immunoprecipitation-small RNA sequencing overlap with 22G-RNAs depleted in cbr-csr-1 RNAi-treated worms. By comparing 22G-RNAs and target genes between species, we defined a set of CSR-1 target genes with conserved germline expression, enrichment in operons and more slowly evolving coding sequences than other genes, along with a small group of evolutionarily labile targets. We demonstrate that the association of CSR-1 with chromatin is preserved, and show that depletion of cbr-csr-1 leads to chromosome segregation defects and embryonic lethality. This first comparative characterization of a small RNA pathway in Caenorhabditis establishes a conserved nuclear role for CSR-1 and highlights its key role in germline gene regulation across multiple animal species. PMID:25510497

  3. 26 CFR 1.852-4 - Method of taxation of shareholders of regulated investment companies.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Method of taxation of shareholders of regulated investment companies. 1.852-4 Section 1.852-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... Investment Trusts § 1.852-4 Method of taxation of shareholders of regulated investment companies. (a...

  4. 26 CFR 1.852-4 - Method of taxation of shareholders of regulated investment companies.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 9 2011-04-01 2011-04-01 false Method of taxation of shareholders of regulated investment companies. 1.852-4 Section 1.852-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE... Real Estate Investment Trusts § 1.852-4 Method of taxation of shareholders of regulated investment...

  5. Stakeholders' Responses to CSR Tradeoffs: When Other-Orientation and Trust Trump Material Self-Interest

    PubMed Central

    Bridoux, Flore; Stofberg, Nicole; Den Hartog, Deanne

    2016-01-01

    When investing in corporate social responsibility (CSR), managers may strive for a win-win scenario where all stakeholders end up better off, but they may not always be able to avoid trading off stakeholders' interests. To provide guidance to managers who have to make tradeoffs, this study used a vignette-based experiment to explore stakeholders' intention to associate with a firm (i.e., buy from or become an employee) that trades off CSR directed at the stakeholders' own group (self-directed CSR) and CSR directed at another stakeholder group (other-directed CSR). Results show that stakeholders were not systematically more attracted to a firm that favors their own group over another stakeholder group. Specifically, stakeholders' other-orientation moderated their reaction to tradeoffs: stakeholders higher on other-orientation were willing to forego some material benefits to associate with a firm that treated suppliers in developing countries significantly better than its competitors, whereas stakeholders lower on other-orientation were more attracted to a firm favoring their own stakeholder group. Other-orientation also moderated reactions to tradeoffs involving the environment, although high CSR directed at the environment did not compensate for low self-directed CSR even for stakeholders higher on other-orientation. Second, the vignette study showed that trust mediated the relationship between tradeoffs and stakeholders' reactions. The study contributes first and foremost to the burgeoning literature on CSR tradeoffs and to the multimotive approach to CSR, which claims that other motives can drive stakeholders' reactions to CSR in addition to self-interest. First, it provides further evidence that studying CSR tradeoffs is important to understand both (prospective) employees' and customers' reactions to CSR-related activities. Second, it identifies other-orientation as a motive-related individual difference that explains heterogeneity in stakeholders' reactions to

  6. Stakeholders' Responses to CSR Tradeoffs: When Other-Orientation and Trust Trump Material Self-Interest.

    PubMed

    Bridoux, Flore; Stofberg, Nicole; Den Hartog, Deanne

    2015-01-01

    When investing in corporate social responsibility (CSR), managers may strive for a win-win scenario where all stakeholders end up better off, but they may not always be able to avoid trading off stakeholders' interests. To provide guidance to managers who have to make tradeoffs, this study used a vignette-based experiment to explore stakeholders' intention to associate with a firm (i.e., buy from or become an employee) that trades off CSR directed at the stakeholders' own group (self-directed CSR) and CSR directed at another stakeholder group (other-directed CSR). Results show that stakeholders were not systematically more attracted to a firm that favors their own group over another stakeholder group. Specifically, stakeholders' other-orientation moderated their reaction to tradeoffs: stakeholders higher on other-orientation were willing to forego some material benefits to associate with a firm that treated suppliers in developing countries significantly better than its competitors, whereas stakeholders lower on other-orientation were more attracted to a firm favoring their own stakeholder group. Other-orientation also moderated reactions to tradeoffs involving the environment, although high CSR directed at the environment did not compensate for low self-directed CSR even for stakeholders higher on other-orientation. Second, the vignette study showed that trust mediated the relationship between tradeoffs and stakeholders' reactions. The study contributes first and foremost to the burgeoning literature on CSR tradeoffs and to the multimotive approach to CSR, which claims that other motives can drive stakeholders' reactions to CSR in addition to self-interest. First, it provides further evidence that studying CSR tradeoffs is important to understand both (prospective) employees' and customers' reactions to CSR-related activities. Second, it identifies other-orientation as a motive-related individual difference that explains heterogeneity in stakeholders' reactions to

  7. The Csr/Rsm system of Yersinia and related pathogens: a post-transcriptional strategy for managing virulence.

    PubMed

    Heroven, Ann Kathrin; Böhme, Katja; Dersch, Petra

    2012-04-01

    This review emphasizes the function and regulation of the Csr regulatory system in the human enteropathogen Yersinia pseudotuberculosis and compares its features with the homologous Csr/Rsm systems of related pathogens. The Csr/Rsm systems of eubacteria form a complex regulatory network in which redundant non-translated Csr/Rsm-RNAs bind the RNA-binding protein CsrA/RsmA, thereby preventing its interaction with mRNA targets. The Csr system is controlled by the BarA/UvrY-type of two-component sensor-regulator systems. Apart from that, common or pathogen-specific regulators control the abundance of the Csr components. The coordinate control of virulence factors and infection-linked physiological traits by the Csr/Rsm systems helps the pathogens to adapt individually to rapidly changing conditions to which they are exposed during the different stages of an infection. As Csr/Rsm function is relevant for full virulence, it represents a target suitable for antimicrobial drug development.

  8. Promoting Reading Comprehension, Content Learning, and English Acquisition through Collaborative Strategic Reading (CSR).

    ERIC Educational Resources Information Center

    Klingner, Janette K.; Vaughn, Sharon

    1999-01-01

    Describes procedures for teaching Collaborative Strategic Reading (CSR), in which students of mixed reading and achievement levels work in small, cooperative groups to assist one another in applying reading strategies to facilitate their comprehension of content-area text. Discusses whole-class instruction of CSR strategies, implementing CSR in…

  9. 26 CFR 1.1366-2 - Limitations on deduction of passthrough items of an S corporation to its shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... shareholder's stock in the corporation (as determined under paragraph (a)(3)(i) of this section); and (ii) The... stock in an S corporation and of any indebtedness of the S corporation to the shareholder is not allowed... taxable years, with respect to the shareholder. For rules on determining the adjusted bases of stock of an...

  10. Defining, Measuring and Supporting Success: Meeting the Challenges of Comprehensive School Reform Research. CSR Connection.

    ERIC Educational Resources Information Center

    Appelbaum, Deborah; Schwartzbeck, Terri Duggan

    Many educators believe that comprehensive school reform (CSR) holds real promise for improving schools, as many CSR programs are based in research and have documented success. However, in the past year, there has been increased emphasis on CSR programs' evidence of effectiveness and scrutiny of CSR evaluations' degree of rigor. Questions exist…

  11. Identification of shareholder ethics and responsibilities in online reverse auctions for construction projects.

    PubMed

    Hatipkarasulu, Yilmaz; Gill, James H

    2004-04-01

    The increasing number of companies providing internet services and auction tools helped popularize the online reverse auction trend for purchasing commodities and services in the last decade. As a result, a number of owners, both public and private, accepted the online reverse auctions as the bidding technique for their construction projects. Owners, while trying to minimize their costs for construction projects, are also required to address their ethical responsibilities to the shareholders. In the case of online reverse auctions for construction projects, the ethical issues involved in the bidding technique directly reflects on the owner's ethical and social responsibilities to their shareholders. The goal of this paper is to identify the shareholder ethics and responsibilities in online reverse auctions for construction projects by analyzing the ethical issues for the parties involved in the process. The identification of the ethical issues and responsibilities requires clear definition and understanding of professional ethics and the roles of the involved parties. In this paper, first, the concept of professional ethics and social responsibility is described in a general form. To illustrate the ethical issues and responsibilities, a sample case of bidding for a construction project using online reverse auction techniques is presented in which the shareholders were actively involved in questioning the ethical issues. The issues involved in the bidding process and their reflection on the shareholder responsibilities are described and analyzed for each stage of the process. A brief discussion of the overall process is also included to address the general ethical issues involved in online reverse auctions.

  12. Regulation of host-pathogen interactions via the post-transcriptional Csr/Rsm system.

    PubMed

    Kusmierek, Maria; Dersch, Petra

    2018-02-01

    A successful colonization of specific hosts requires a rapid and efficient adaptation of the virulence-relevant gene expression program by bacterial pathogens. An important element in this endeavor is the Csr/Rsm system. This multi-component, post-transcriptional control system forms a central hub within complex regulatory networks and coordinately adjusts virulence properties with metabolic and physiological attributes of the pathogen. A key function is elicited by the RNA-binding protein CsrA/RsmA. CsrA/RsmA interacts with numerous target mRNAs, many of which encode crucial virulence factors, and alters their translation, stability or elongation of transcription. Recent studies highlighted that important colonization factors, toxins, and bacterial secretion systems are under CsrA/RsmA control. CsrA/RsmA deficiency impairs host colonization and attenuates virulence, making this post-transcriptional regulator a suitable drug target. The CsrA/RsmA protein can be inactivated through sequestration by non-coding RNAs, or via binding to specific highly abundant mRNAs and interacting proteins. The wide range of interaction partners and RNA targets, as well as the overarching, interlinked genetic control circuits illustrate the complexity of this regulatory system in the different pathogens. Future work addressing spatio-temporal changes of Csr/Rsm-mediated control during the course of an infection will help us to understand how bacteria reprogram their expression profile to cope with continuous changes experienced in colonized niches. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Comparative functional characterization of the CSR-1 22G-RNA pathway in Caenorhabditis nematodes.

    PubMed

    Tu, Shikui; Wu, Monica Z; Wang, Jie; Cutter, Asher D; Weng, Zhiping; Claycomb, Julie M

    2015-01-01

    As a champion of small RNA research for two decades, Caenorhabditis elegans has revealed the essential Argonaute CSR-1 to play key nuclear roles in modulating chromatin, chromosome segregation and germline gene expression via 22G-small RNAs. Despite CSR-1 being preserved among diverse nematodes, the conservation and divergence in function of the targets of small RNA pathways remains poorly resolved. Here we apply comparative functional genomic analysis between C. elegans and Caenorhabditis briggsae to characterize the CSR-1 pathway, its targets and their evolution. C. briggsae CSR-1-associated small RNAs that we identified by immunoprecipitation-small RNA sequencing overlap with 22G-RNAs depleted in cbr-csr-1 RNAi-treated worms. By comparing 22G-RNAs and target genes between species, we defined a set of CSR-1 target genes with conserved germline expression, enrichment in operons and more slowly evolving coding sequences than other genes, along with a small group of evolutionarily labile targets. We demonstrate that the association of CSR-1 with chromatin is preserved, and show that depletion of cbr-csr-1 leads to chromosome segregation defects and embryonic lethality. This first comparative characterization of a small RNA pathway in Caenorhabditis establishes a conserved nuclear role for CSR-1 and highlights its key role in germline gene regulation across multiple animal species. © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research.

  14. Campylobacter jejuni CsrA Regulates Metabolic and Virulence Associated Proteins and Is Necessary for Mouse Colonization.

    PubMed

    Fields, Joshua A; Li, Jiaqi; Gulbronson, Connor J; Hendrixson, David R; Thompson, Stuart A

    2016-01-01

    Campylobacter jejuni infection is a leading bacterial cause of gastroenteritis and a common antecedent leading to Gullian-Barré syndrome. Our previous data suggested that the RNA-binding protein CsrA plays an important role in regulating several important phenotypes including motility, biofilm formation, and oxidative stress resistance. In this study, we compared the proteomes of wild type, csrA mutant, and complemented csrA mutant C. jejuni strains in an effort to elucidate the mechanisms by which CsrA affects virulence phenotypes. The putative CsrA regulon was more pronounced at stationary phase (111 regulated proteins) than at mid-log phase (25 regulated proteins). Proteins displaying altered expression in the csrA mutant included diverse metabolic functions, with roles in amino acid metabolism, TCA cycle, acetate metabolism, and various other cell processes, as well as pathogenesis-associated characteristics such as motility, chemotaxis, oxidative stress resistance, and fibronectin binding. The csrA mutant strain also showed altered autoagglutination kinetics when compared to the wild type. CsrA specifically bound the 5' end of flaA mRNA, and we demonstrated that CsrA is a growth-phase dependent repressor of FlaA expression. Finally, the csrA mutant exhibited reduced ability to colonize in a mouse model when in competition with the wild type, further underscoring the role of CsrA in C. jejuni colonization and pathogenesis.

  15. Campylobacter jejuni CsrA Regulates Metabolic and Virulence Associated Proteins and Is Necessary for Mouse Colonization

    PubMed Central

    Fields, Joshua A.; Li, Jiaqi; Gulbronson, Connor J.; Hendrixson, David R.

    2016-01-01

    Campylobacter jejuni infection is a leading bacterial cause of gastroenteritis and a common antecedent leading to Gullian-Barré syndrome. Our previous data suggested that the RNA-binding protein CsrA plays an important role in regulating several important phenotypes including motility, biofilm formation, and oxidative stress resistance. In this study, we compared the proteomes of wild type, csrA mutant, and complemented csrA mutant C. jejuni strains in an effort to elucidate the mechanisms by which CsrA affects virulence phenotypes. The putative CsrA regulon was more pronounced at stationary phase (111 regulated proteins) than at mid-log phase (25 regulated proteins). Proteins displaying altered expression in the csrA mutant included diverse metabolic functions, with roles in amino acid metabolism, TCA cycle, acetate metabolism, and various other cell processes, as well as pathogenesis-associated characteristics such as motility, chemotaxis, oxidative stress resistance, and fibronectin binding. The csrA mutant strain also showed altered autoagglutination kinetics when compared to the wild type. CsrA specifically bound the 5’ end of flaA mRNA, and we demonstrated that CsrA is a growth-phase dependent repressor of FlaA expression. Finally, the csrA mutant exhibited reduced ability to colonize in a mouse model when in competition with the wild type, further underscoring the role of CsrA in C. jejuni colonization and pathogenesis. PMID:27257952

  16. Dynamic CO₂ inhalation: a novel treatment for CSR-CSA associated with CHF.

    PubMed

    Wan, Zhi Hui; Wen, Fang Jing; Hu, Ke

    2013-05-01

    Cheyne-Stokes respiration with central sleep apnea (CSR-CSA) is very common in patients with chronic congestive heart failure (CHF). A current concept of the key pathophysiological mechanism leading to CSR-CSA is a fluctuation of PaCO2 below and above the apneic threshold. A number of therapeutic approaches for CSR-CSA have been proposed-all with varying success, some of which include various modes of positive airway pressure among other strategies. However, CO2 oscillations seen in CSR-CSA have yet to be looked at as a specific therapeutic target by current treatments. Previous studies have shown that delivery of constant CO2 is efficacious in eliminating CSR-CSA by raising PaCO2, but there are serious concerns about the potential side effects, such as unwanted elevations in ventilation, work of breathing, and sympathetic nerve activity (SNA), and consequently CO2 inhalation therapy has not been recommended as a routine option for therapy. However, recent new studies into CO2 inhalation therapy have been made that may reshape its role as therapeutic. In this review, we will focus on the recent developments of administration of dynamic CO2 in the management of CSR-CSA in CHF patients.

  17. To Sell or Not to Sell? Behavior of Shareholders During Price Collapses

    NASA Astrophysics Data System (ADS)

    Roehner, Bertrand M.

    It is a common belief that the behavior of shareholders depends upon the direction of price fluctuations: if prices increase they buy, if prices decrease they sell. That belief, however, is more based on ``common sense'' than on facts. In this paper, we present evidence for a specific class of shareholders which shows that the actual behavior of shareholders can be markedly different. For instance, they may continue to buy despite a prolonged fall in prices or they may sell even though prices climb. A closer analysis shows that a substantial proportion of investors are more influenced by the ``general social climate'' than by actual price changes. The percentage of speculative investors who optimize their portfolio on a monthly basis can be estimated and turns out to be about 5 to 10%. The results presented in this paper can be of usefulness in order to test the assumptions or the results of market simulations and models.

  18. 26 CFR 1.857-6 - Method of taxation of shareholders of real estate investment trusts.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 9 2010-04-01 2010-04-01 false Method of taxation of shareholders of real estate investment trusts. 1.857-6 Section 1.857-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT...-6 Method of taxation of shareholders of real estate investment trusts. (a) Ordinary income. Except...

  19. Will Green CSR Enhance Innovation? A Perspective of Public Visibility and Firm Transparency.

    PubMed

    Wu, Weiwei; Liu, Yexin; Chin, Tachia; Zhu, Wenzhong

    2018-02-04

    In response to the asking and requiring of stakeholders to be more environmentally responsible, firms must commit to green corporate social responsibility (CSR). Firms being green and responsible always can acquire intangible resources that are important for firm innovation. Given the scarcity of existing research addressing relevant issues in depth, this paper expands our understanding of green CSR by revealing its antecedent effects on firm innovation performance. We also include public visibility and firm transparency as contingency factors to explore the relationship between green CSR and firm innovation performance. Using data collected from publicly listed firms in China, we find that greater innovation performance is associated with an increase in firm green CSR, and the positive relationship between green CSR and innovation performance is moderated by public visibility and firm transparency. Based on the results, theoretical contributions and practical implications are outlined.

  20. 26 CFR 1.853-3 - Notice to shareholders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ...) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.853-3 Notice to shareholders. (a) General rule. If a regulated investment company makes an election under section 853(a), in the manner provided in § 1.853-4, the regulated investment company is required under...

  1. 26 CFR 1.853-3 - Notice to shareholders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ...) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.853-3 Notice to shareholders. (a) General rule. If a regulated investment company makes an election under section 853(a), in the manner provided in § 1.853-4, the regulated investment company is required under...

  2. 26 CFR 1.853-3 - Notice to shareholders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ...) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.853-3 Notice to shareholders. (a) General rule. If a regulated investment company makes an election under section 853(a), in the manner provided in § 1.853-4, the regulated investment company is required under...

  3. 26 CFR 1.853-3 - Notice to shareholders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ...) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.853-3 Notice to shareholders. (a) General rule. If a regulated investment company makes an election under section 853(a), in the manner provided in § 1.853-4, the regulated investment company is required under...

  4. Requirements management: A CSR's perspective

    NASA Technical Reports Server (NTRS)

    Thompson, Joanie

    1991-01-01

    The following subject areas are covered: customer service overview of network service request processing; Customer Service Representative (CSR) responsibility matrix; extract from a sample Memorandum of Understanding; Network Service Request Form and its instructions sample notification of receipt; and requirements management in the NASA Science Internet.

  5. Will Green CSR Enhance Innovation? A Perspective of Public Visibility and Firm Transparency

    PubMed Central

    Wu, Weiwei; Liu, Yexin; Chin, Tachia; Zhu, Wenzhong

    2018-01-01

    In response to the asking and requiring of stakeholders to be more environmentally responsible, firms must commit to green corporate social responsibility (CSR). Firms being green and responsible always can acquire intangible resources that are important for firm innovation. Given the scarcity of existing research addressing relevant issues in depth, this paper expands our understanding of green CSR by revealing its antecedent effects on firm innovation performance. We also include public visibility and firm transparency as contingency factors to explore the relationship between green CSR and firm innovation performance. Using data collected from publicly listed firms in China, we find that greater innovation performance is associated with an increase in firm green CSR, and the positive relationship between green CSR and innovation performance is moderated by public visibility and firm transparency. Based on the results, theoretical contributions and practical implications are outlined. PMID:29401714

  6. 26 CFR 1.857-6 - Method of taxation of shareholders of real estate investment trusts.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 9 2011-04-01 2011-04-01 false Method of taxation of shareholders of real estate investment trusts. 1.857-6 Section 1.857-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT... Trusts § 1.857-6 Method of taxation of shareholders of real estate investment trusts. (a) Ordinary income...

  7. CSR-1 RNAi pathway positively regulates histone expression in C. elegans

    PubMed Central

    Avgousti, Daphne C; Palani, Santhosh; Sherman, Yekaterina; Grishok, Alla

    2012-01-01

    Endogenous small interfering RNAs (endo-siRNAs) have been discovered in many organisms, including mammals. In C. elegans, depletion of germline-enriched endo-siRNAs found in complex with the CSR-1 Argonaute protein causes sterility and defects in chromosome segregation in early embryos. We discovered that knockdown of either csr-1, the RNA-dependent RNA polymerase (RdRP) ego-1, or the dicer-related helicase drh-3, leads to defects in histone mRNA processing, resulting in severe depletion of core histone proteins. The maturation of replication-dependent histone mRNAs, unlike that of other mRNAs, requires processing of their 3′UTRs through an endonucleolytic cleavage guided by the U7 snRNA, which is lacking in C. elegans. We found that CSR-1-bound antisense endo-siRNAs match histone mRNAs and mRNA precursors. Consistently, we demonstrate that CSR-1 directly binds to histone mRNA in an ego-1-dependent manner using biotinylated 2′-O-methyl RNA oligonucleotides. Moreover, we demonstrate that increasing the dosage of histone genes rescues the lethality associated with depletion of CSR-1 and EGO-1. These results support a positive and direct effect of RNAi on histone gene expression. PMID:22863779

  8. CSR-1 RNAi pathway positively regulates histone expression in C. elegans.

    PubMed

    Avgousti, Daphne C; Palani, Santhosh; Sherman, Yekaterina; Grishok, Alla

    2012-10-03

    Endogenous small interfering RNAs (endo-siRNAs) have been discovered in many organisms, including mammals. In C. elegans, depletion of germline-enriched endo-siRNAs found in complex with the CSR-1 Argonaute protein causes sterility and defects in chromosome segregation in early embryos. We discovered that knockdown of either csr-1, the RNA-dependent RNA polymerase (RdRP) ego-1, or the dicer-related helicase drh-3, leads to defects in histone mRNA processing, resulting in severe depletion of core histone proteins. The maturation of replication-dependent histone mRNAs, unlike that of other mRNAs, requires processing of their 3'UTRs through an endonucleolytic cleavage guided by the U7 snRNA, which is lacking in C. elegans. We found that CSR-1-bound antisense endo-siRNAs match histone mRNAs and mRNA precursors. Consistently, we demonstrate that CSR-1 directly binds to histone mRNA in an ego-1-dependent manner using biotinylated 2'-O-methyl RNA oligonucleotides. Moreover, we demonstrate that increasing the dosage of histone genes rescues the lethality associated with depletion of CSR-1 and EGO-1. These results support a positive and direct effect of RNAi on histone gene expression.

  9. CSR: Constrained Selfish Routing in Ad-Hoc Networks

    NASA Astrophysics Data System (ADS)

    Bassem, Christine; Bestavros, Azer

    Routing protocols for ad-hoc networks assume that the nodes forming the network are either under a single authority, or else that they would be altruistically forwarding data for other nodes with no expectation of a return. These assumptions are unrealistic since in ad-hoc networks, nodes are likely to be autonomous and rational (selfish), and thus unwilling to help unless they have an incentive to do so. Providing such incentives is an important aspect that should be considered when designing ad-hoc routing protocols. In this paper, we propose a dynamic, decentralized routing protocol for ad-hoc networks that provides incentives in the form of payments to intermediate nodes used to forward data for others. In our Constrained Selfish Routing (CSR) protocol, game-theoretic approaches are used to calculate payments (incentives) that ensure both the truthfulness of participating nodes and the fairness of the CSR protocol. We show through simulations that CSR is an energy efficient protocol and that it provides lower communication overhead in the best and average cases compared to existing approaches.

  10. Annual Reports to Shareholders: Historical Collections in Libraries

    ERIC Educational Resources Information Center

    Nixon, Judith M.

    2010-01-01

    The purpose of this article is to describe the scope and depth of the historic corporate annual report collections in twelve academic/research libraries in North America. For many decades, a few major academic business libraries have been collecting and preserving corporate Annual Reports (ARS), the reports sent to shareholders documenting the…

  11. 26 CFR 1.853-3 - Notice to shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) INCOME TAXES Regulated Investment Companies and Real Estate Investment Trusts § 1.853-3 Notice to shareholders. (a) General rule. If a regulated investment company makes an election under section 853(a), in the manner provided in § 1.853-4, the regulated investment company is required under section 853(c) to...

  12. 24 CFR 1710.504 - Cooperation among certified states and between certified states and the Secretary.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Cooperation among certified states....504 Cooperation among certified states and between certified states and the Secretary. (a) By filing... situs certified state authorities within 15 days of the date on which the developer knows, or should...

  13. Structural Rearrangement in an RsmA/CsrA Ortholog of Pseudomonas aeruginosa Creates a Dimeric RNA-Binding Protein, RsmN

    PubMed Central

    Morris, Elizabeth R.; Hall, Gareth; Li, Chan; Heeb, Stephan; Kulkarni, Rahul V.; Lovelock, Laura; Silistre, Hazel; Messina, Marco; Cámara, Miguel; Emsley, Jonas; Williams, Paul; Searle, Mark S.

    2013-01-01

    Summary In bacteria, the highly conserved RsmA/CsrA family of RNA-binding proteins functions as global posttranscriptional regulators acting on mRNA translation and stability. Through phenotypic complementation of an rsmA mutant in Pseudomonas aeruginosa, we discovered a family member, termed RsmN. Elucidation of the RsmN crystal structure and that of the complex with a hairpin from the sRNA, RsmZ, reveals a uniquely inserted α helix, which redirects the polypeptide chain to form a distinctly different protein fold to the domain-swapped dimeric structure of RsmA homologs. The overall β sheet structure required for RNA recognition is, however, preserved with compensatory sequence and structure differences, allowing the RsmN dimer to target binding motifs in both structured hairpin loops and flexible disordered RNAs. Phylogenetic analysis indicates that, although RsmN appears unique to P. aeruginosa, homologous proteins with the inserted α helix are more widespread and arose as a consequence of a gene duplication event. PMID:23954502

  14. The RNA-binding protein CsrA plays a central role in positively regulating virulence factors in Erwinia amylovora

    PubMed Central

    Ancona, Veronica; Lee, Jae Hoon; Zhao, Youfu

    2016-01-01

    The GacS/GacA two-component system (also called GrrS/GrrA) is a global regulatory system which is highly conserved among gamma-proteobacteria. This system positively regulates non-coding small regulatory RNA csrB, which in turn binds to the RNA-binding protein CsrA. However, how GacS/GacA-Csr system regulates virulence traits in E. amylovora remains unknown. Results from mutant characterization showed that the csrB mutant was hypermotile, produced higher amount of exopolysaccharide amylovoran, and had increased expression of type III secretion (T3SS) genes in vitro. In contrast, the csrA mutant exhibited complete opposite phenotypes, including non-motile, reduced amylovoran production and expression of T3SS genes. Furthermore, the csrA mutant did not induce hypersensitive response on tobacco or cause disease on immature pear fruits, indicating that CsrA is a positive regulator of virulence factors. These findings demonstrated that CsrA plays a critical role in E. amylovora virulence and suggested that negative regulation of virulence by GacS/GacA acts through csrB sRNA, which binds to CsrA and neutralizes its positive effect on T3SS gene expression, flagellar formation and amylovoran production. Future research will be focused on determining the molecular mechanism underlying the positive regulation of virulence traits by CsrA. PMID:27845410

  15. The RNA-binding protein CsrA plays a central role in positively regulating virulence factors in Erwinia amylovora.

    PubMed

    Ancona, Veronica; Lee, Jae Hoon; Zhao, Youfu

    2016-11-15

    The GacS/GacA two-component system (also called GrrS/GrrA) is a global regulatory system which is highly conserved among gamma-proteobacteria. This system positively regulates non-coding small regulatory RNA csrB, which in turn binds to the RNA-binding protein CsrA. However, how GacS/GacA-Csr system regulates virulence traits in E. amylovora remains unknown. Results from mutant characterization showed that the csrB mutant was hypermotile, produced higher amount of exopolysaccharide amylovoran, and had increased expression of type III secretion (T3SS) genes in vitro. In contrast, the csrA mutant exhibited complete opposite phenotypes, including non-motile, reduced amylovoran production and expression of T3SS genes. Furthermore, the csrA mutant did not induce hypersensitive response on tobacco or cause disease on immature pear fruits, indicating that CsrA is a positive regulator of virulence factors. These findings demonstrated that CsrA plays a critical role in E. amylovora virulence and suggested that negative regulation of virulence by GacS/GacA acts through csrB sRNA, which binds to CsrA and neutralizes its positive effect on T3SS gene expression, flagellar formation and amylovoran production. Future research will be focused on determining the molecular mechanism underlying the positive regulation of virulence traits by CsrA.

  16. 17 CFR 240.14a-8 - Shareholder proposals.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., the company must also provide in the form of proxy means for shareholders to specify by boxes a choice... held at least $2,000 in market value, or 1%, of the company's securities entitled to be voted on the... writing of any procedural or eligibility deficiencies, as well as of the time frame for your response...

  17. 12 CFR 215.9 - Disclosure of credit from member banks to executive officers and principal shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Disclosure of credit from member banks to executive officers and principal shareholders. 215.9 Section 215.9 Banks and Banking FEDERAL RESERVE SYSTEM... includes a person that controls a principal shareholder (e.g., a person that controls a bank holding...

  18. An investigation of safety climate in OHSAS 18001-certified and non-certified organizations.

    PubMed

    Ghahramani, Abolfazl

    2016-09-01

    Many organizations worldwide have implemented Occupational Health and Safety Assessment Series (OHSAS) 18001 in their premises because of the assumed positive effects of this standard on safety. Few studies have analyzed the effect of the safety climate in OHSAS 18001-certified organizations. This case-control study used a new safety climate questionnaire to evaluate three OHSAS 18001-certified and three non-certified manufacturing companies in Iran. Hierarchical regression indicated that the safety climate was influenced by OHSAS implementation and by safety training. Employees who received safety training had better perceptions of the safety climate and its dimensions than other respondents within the certified companies. This study found that the implementation of OHSAS 18001 does not guarantee improvement of the safety climate. This study also emphasizes the need for high-quality safety training for employees of the certified companies to improve the safety climate.

  19. Effects of the Global Regulator CsrA on the BarA/UvrY Two-Component Signaling System

    PubMed Central

    Camacho, Martha I.; Alvarez, Adrian F.; Gonzalez Chavez, Ricardo; Romeo, Tony; Merino, Enrique

    2014-01-01

    The hybrid sensor kinase BarA and its cognate response regulator UvrY, members of the two-component signal transduction family, activate transcription of CsrB and CsrC noncoding RNAs. These two small RNAs act by sequestering the RNA binding protein CsrA, which posttranscriptionally regulates translation and/or stability of its target mRNAs. Here, we provide evidence that CsrA positively affects, although indirectly, uvrY expression, at both the transcriptional and translational levels. We also demonstrate that CsrA is required for properly switching BarA from its phosphatase to its kinase activity. Thus, the existence of a feedback loop mechanism that involves the Csr and BarA/UvrY global regulatory systems is exposed. PMID:25535275

  20. Effects of Cryogenic Temperature on Fracture Toughness of Core-Shell Rubber (CSR) Toughened Epoxy Nanocomposites

    NASA Technical Reports Server (NTRS)

    Wang, J.; Cannon, S. A.; Magee, D.; Schneider, J. A.

    2008-01-01

    This study investigated the effects of core-shell rubber (CSR) nanoparticles on the mechanical properties and fracture toughness of an epoxy resin at ambient and liquid nitrogen (LN2) temperatures. Varying amounts of Kane Ace MX130 toughening agent were added to a commercially available EPON 862/Epikure W epoxy resin. Elastic modulus was calculated using quasi-static tensile data. Fracture toughness was evaluated by the resulting breaking energy measured in Charpy impact tests conducted on an instrumented drop tower. The size and distribution of the CSR nanoparticles were characterized using Transmission Electron Microscopy (TEM) and Small Angle X-ray Scattering (SAXS). Scanning Electron Microscopy (SEM) was used to study the fracture surface morphology. The addition of the CSR nanoparticles increased the breaking energy with negligible change in elastic modulus and ultimate tensile stress (UTS). At ambient temperature the breaking energy increased with increasing additions of the CSR nanoparticles, while at LN2 temperatures, it reached a maximum at 5 wt% CSR concentration. KEY WORDS: liquid nitrogen (LN2) properties, fracture toughness, core-shell rubber (CSR).

  1. Causes of fatal accidents for instrument-certified and non-certified private pilots.

    PubMed

    Shao, Bob Siyuan; Guindani, Michele; Boyd, Douglas D

    2014-11-01

    Instrument certification (IFR) enhances a pilot's skills in precisely controlling the aircraft and requires a higher level of standards in maintaining heading and altitude compared with the less stringent private pilot certificate. However, there have been no prior studies to compare fatal accident causes for airmen with, and without, this rating, The NTSB accident database was queried for general aviation fatal accidents for private pilots with, and without IFR certification. Exact Poisson tests were used to calculate whether two rate parameters were equal (ratio of 1), normalized to the number of IFR-rated pilots and flight hours in the given time period. Proportion tests were used to determine whether there were significant differences in fatal accident causes between IFR-certified and non-certified pilots. A logistic regression for log-odds success was used in determining the trend and effect of age on fatal accident rates. IFR certification was associated with a reduced risk of accidents due to failure to maintain obstacle/terrain clearance and spatial disorientation for day and night operations respectively. In contrast, the likelihood of fatal accident due to equipment malfunction during day operations was higher for IFR-certified pilots. The fatal accident rate decreased over the last decade for IFR-certified but not for non-IFR-certified private pilots. However, the overall accident rate for IFR-certified private pilots was more than double that of the cohort lacking this certification. Finally, we found a trend for an increased fatality rate with advancing age for both group of pilots. Our findings informs on where training and/or technology should be focused. Both training for aerodynamic stalls, which causes over a quarter of all fatal accidents, should be intensified for both IFR-certified and non-certified private pilots. Similarly, adherence to minimum safe altitudes for both groups of pilots should be encouraged toward reducing the fatal accidents

  2. The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system

    PubMed Central

    Sahr, Tobias; Rusniok, Christophe; Impens, Francis; Oliva, Giulia; Sismeiro, Odile; Coppée, Jean-Yves

    2017-01-01

    The carbon storage regulator protein CsrA regulates cellular processes post-transcriptionally by binding to target-RNAs altering translation efficiency and/or their stability. Here we identified and analyzed the direct targets of CsrA in the human pathogen Legionella pneumophila. Genome wide transcriptome, proteome and RNA co-immunoprecipitation followed by deep sequencing of a wild type and a csrA mutant strain identified 479 RNAs with potential CsrA interaction sites located in the untranslated and/or coding regions of mRNAs or of known non-coding sRNAs. Further analyses revealed that CsrA exhibits a dual regulatory role in virulence as it affects the expression of the regulators FleQ, LqsR, LetE and RpoS but it also directly regulates the timely expression of over 40 Dot/Icm substrates. CsrA controls its own expression and the stringent response through a regulatory feedback loop as evidenced by its binding to RelA-mRNA and links it to quorum sensing and motility. CsrA is a central player in the carbon, amino acid, fatty acid metabolism and energy transfer and directly affects the biosynthesis of cofactors, vitamins and secondary metabolites. We describe the first L. pneumophila riboswitch, a thiamine pyrophosphate riboswitch whose regulatory impact is fine-tuned by CsrA, and identified a unique regulatory mode of CsrA, the active stabilization of RNA anti-terminator conformations inside a coding sequence preventing Rho-dependent termination of the gap operon through transcriptional polarity effects. This allows L. pneumophila to regulate the pentose phosphate pathway and the glycolysis combined or individually although they share genes in a single operon. Thus the L. pneumophila genome has evolved to acclimate at least five different modes of regulation by CsrA giving it a truly unique position in its life cycle. PMID:28212376

  3. Global effects of the CSR-1 RNA interference pathway on transcriptional landscape

    PubMed Central

    Cecere, Germano; Hoersch, Sebastian; O’Keeffe, Sean; Sachidanandam, Ravi; Grishok, Alla

    2014-01-01

    Argonaute proteins and their small RNA co-factors short interfering RNAs (siRNAs) are known to inhibit gene expression at the transcriptional and post-transcriptional levels. In Caenorhabditis elegans, the Argonaute CSR-1 binds thousands of endogenous siRNAs (endo-siRNAs) antisense to germline transcripts and associates with chromatin in a siRNA-dependent manner. However, its role in gene expression regulation remains controversial. Here, we used a genome-wide profiling of nascent RNA transcripts to demonstrate that the CSR-1 RNAi pathway promotes sense-oriented Pol II transcription. Moreover, a loss of CSR-1 function resulted in global increase in antisense transcription and ectopic transcription of silent chromatin domains, which led to reduced chromatin incorporation of centromere-specific histone H3. Based on these findings, we propose that the CSR-1 pathway has a role in maintaining the directionality of active transcription thereby propagating the distinction between transcriptionally active and silent genomic regions. PMID:24681887

  4. 17 CFR 240.14a-17 - Electronic shareholder forums.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Electronic shareholder forums. 240.14a-17 Section 240.14a-17 Commodity and Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) GENERAL RULES AND REGULATIONS, SECURITIES EXCHANGE ACT OF 1934 Rules and Regulations Under the...

  5. Adaptation of Tri-molecular fluorescence complementation allows assaying of regulatory Csr RNA-protein interactions in bacteria.

    PubMed

    Gelderman, Grant; Sivakumar, Anusha; Lipp, Sarah; Contreras, Lydia

    2015-02-01

    sRNAs play a significant role in controlling and regulating cellular metabolism. One of the more interesting aspects of certain sRNAs is their ability to make global changes in the cell by interacting with regulatory proteins. In this work, we demonstrate the use of an in vivo Tri-molecular Fluorescence Complementation assay to detect and visualize the central regulatory sRNA-protein interaction of the Carbon Storage Regulatory system in E. coli. The Carbon Storage Regulator consists primarily of an RNA binding protein, CsrA, that alters the activity of mRNA targets and of an sRNA, CsrB, that modulates the activity of CsrA. We describe the construction of a fluorescence complementation system that detects the interactions between CsrB and CsrA. Additionally, we demonstrate that the intensity of the fluorescence of this system is able to detect changes in the affinity of the CsrB-CsrA interaction, as caused by mutations in the protein sequence of CsrA. While previous methods have adopted this technique to study mRNA or RNA localization, this is the first attempt to use this technique to study the sRNA-protein interaction directly in bacteria. This method presents a potentially powerful tool to study complex bacterial RNA protein interactions in vivo. © 2014 Wiley Periodicals, Inc.

  6. Who should set CEO pay? The press? Congress? Shareholders?

    PubMed

    Brownstein, A R; Panner, M J

    1992-01-01

    Populist fervor in an election year has transformed executive compensation from a business issue into a political one. Critics, led by Graef Crystal, author of In Search of Excess: The Overcompensation of American Executives, charge that CEOs are ripping off shareholders with their outrageous salaries while running U.S. corporations into the ground. Politicians claim overpaid CEOs are the root cause of the U.S. competitiveness problem. Add a recessionary business climate to the fact that some CEOs earn 130 times more than their lowest paid employees, and you have the makings of a populist rebellion. In a bid to appease voters, Congress is considering several bills that would limit the deductibility of "excessive executive salaries," the SEC has opened the issue to shareholder comment, and the Financial Accounting Standards Board is looking at new accounting standards for granting stock options to executives as part of company compensation schemes. Andrew R. Brownstein and Morris J. Panner say it's time to put the debate back where it belongs--in a business context. The real question is not are executives paid too much, but are shareholders getting their money's worth. Most U.S. corporations use stock compensation to link company long-term performance to executive salaries. And because of the staggering market performance of U.S. corporations in the 1980s, an overwhelming majority of CEOs are actually paid in line with their performance. Rather than cut executive pay, Brownstein and Panner suggest that corporations extend incentive-based compensation plans to all employees, thus narrowing the salary gap and establishing pay for performance at every level of the organization.

  7. 17 CFR 240.14a-8 - Shareholder proposals.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Exchange Act of 1934 Regulation 14a: Solicitation of Proxies § 240.14a-8 Shareholder proposals. Link to an amendment published at 75 FR 56782, Sept. 16, 2010. Link to a delay published at 75 FR 64641, Oct. 20, 2010. Link to an amendment published at 76 FR 6045, Feb. 2, 2011. This section addresses when a company must...

  8. Communicating CSR and Business Identity in the Chemical Industry through Mission Slogans

    ERIC Educational Resources Information Center

    Verboven, Hans

    2011-01-01

    This article analyzes the communication of corporate social responsibility (CSR) and corporate image in the chemical industry through mission slogans. Morsing's (2006) CSR communication framework is adapted for a comparative analysis of the strategies behind mission slogans. By grouping rhetorical strategies in a mission slogan into a mission…

  9. Which CSR-Related Headings Do "Fortune" 500 Companies Use on Their Websites?

    ERIC Educational Resources Information Center

    Smith, Katherine Taken; Alexander, Julie J.

    2013-01-01

    This article examines website headings used by "Fortune" 500 companies in their efforts to inform stakeholders about corporate social responsibility (CSR). Instead of using "Corporate Social Responsibility" as a heading, companies often use specific terms to identify various CSR initiatives. The purpose of this article is to identify common…

  10. 78 FR 62418 - Application of the Segregation Rules to Small Shareholders

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-22

    ... 382 policies because the capital infusion can accelerate the use of tax attributes. This is the case... shareholders of the loss corporation. Furthermore, because infusions of capital into the loss corporation...

  11. The carbon storage regulator (Csr) system exerts a nutrient-specific control over central metabolism in Escherichia coli strain Nissle 1917.

    PubMed

    Revelles, Olga; Millard, Pierre; Nougayrède, Jean-Philippe; Dobrindt, Ulrich; Oswald, Eric; Létisse, Fabien; Portais, Jean-Charles

    2013-01-01

    The role of the post-transcriptional carbon storage regulator (Csr) system in nutrient utilization and in the control of the central metabolism in E. coli reference commensal strain Nissle 1917 was investigated. Analysis of the growth capabilities of mutants altered for various components of the Csr system (csrA51, csrB, csrC and csrD mutations) showed that only the protein CsrA - the key component of the system - exerts a marked role in carbon nutrition. Attenuation of CsrA activity in the csrA51 mutant affects the growth efficiency on a broad range of physiologically relevant carbon sources, including compounds utilized by the Entner-Doudoroff (ED) pathway. Detailed investigations of the metabolomes and fluxomes of mutants and wild-type cells grown on carbon sources representative of glycolysis and of the ED pathway (glucose and gluconate, respectively), revealed significant re-adjusting of central carbon metabolism for both compounds in the csrA51 mutant. However, the metabolic re-adjusting observed on gluconate was strikingly different from that observed on glucose, indicating a nutrient-specific control of metabolism by the Csr system.

  12. The Carbon Storage Regulator (Csr) System Exerts a Nutrient-Specific Control over Central Metabolism in Escherichia coli Strain Nissle 1917

    PubMed Central

    Nougayrède, Jean-Philippe; Dobrindt, Ulrich; Oswald, Eric; Létisse, Fabien; Portais, Jean-Charles

    2013-01-01

    The role of the post-transcriptional carbon storage regulator (Csr) system in nutrient utilization and in the control of the central metabolism in E. coli reference commensal strain Nissle 1917 was investigated. Analysis of the growth capabilities of mutants altered for various components of the Csr system (csrA51, csrB, csrC and csrD mutations) showed that only the protein CsrA - the key component of the system - exerts a marked role in carbon nutrition. Attenuation of CsrA activity in the csrA51 mutant affects the growth efficiency on a broad range of physiologically relevant carbon sources, including compounds utilized by the Entner-Doudoroff (ED) pathway. Detailed investigations of the metabolomes and fluxomes of mutants and wild-type cells grown on carbon sources representative of glycolysis and of the ED pathway (glucose and gluconate, respectively), revealed significant re-adjusting of central carbon metabolism for both compounds in the csrA51 mutant. However, the metabolic re-adjusting observed on gluconate was strikingly different from that observed on glucose, indicating a nutrient-specific control of metabolism by the Csr system. PMID:23840455

  13. 12 CFR 620.6 - Disclosures in the annual report to shareholders relating to directors and senior officers.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... ADMINISTRATION FARM CREDIT SYSTEM DISCLOSURE TO SHAREHOLDERS Annual Report to Shareholders § 620.6 Disclosures in... group without naming them. (i) If applicable, when any employee who is not a senior officer has annual..., include the highly compensated employee(s) in the aggregate number and amount of compensation reported in...

  14. 12 CFR 620.6 - Disclosures in the annual report to shareholders relating to directors and senior officers.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... ADMINISTRATION FARM CREDIT SYSTEM DISCLOSURE TO SHAREHOLDERS Annual Report to Shareholders § 620.6 Disclosures in... group without naming them. (i) If applicable, when any employee who is not a senior officer has annual..., include the highly compensated employee(s) in the aggregate number and amount of compensation reported in...

  15. 17 CFR 240.14a-18 - Disclosure regarding nominating shareholders and nominees submitted for inclusion in a registrant...

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... nominating shareholders and nominees submitted for inclusion in a registrant's proxy materials pursuant to... nominees submitted for inclusion in a registrant's proxy materials pursuant to applicable state or foreign... governing documents addressing the inclusion of shareholder director nominees in the registrant's proxy...

  16. 17 CFR 240.14a-18 - Disclosure regarding nominating shareholders and nominees submitted for inclusion in a registrant...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... nominating shareholders and nominees submitted for inclusion in a registrant's proxy materials pursuant to... nominees submitted for inclusion in a registrant's proxy materials pursuant to applicable state or foreign... governing documents addressing the inclusion of shareholder director nominees in the registrant's proxy...

  17. 17 CFR 240.14a-18 - Disclosure regarding nominating shareholders and nominees submitted for inclusion in a registrant...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... nominating shareholders and nominees submitted for inclusion in a registrant's proxy materials pursuant to... nominees submitted for inclusion in a registrant's proxy materials pursuant to applicable state or foreign... governing documents addressing the inclusion of shareholder director nominees in the registrant's proxy...

  18. CSR Fields: Direct Numerical Solution of the Maxwell___s Equation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Novokhatski, A.; /SLAC

    2011-06-22

    We discuss the properties of the coherent electromagnetic fields of a very short, ultra-relativistic bunch in a rectangular vacuum chamber inside a bending magnet. The analysis is based on the results of a direct numerical solution of Maxwell's equations together with Newton's equations. We use a new dispersion-free time-domain algorithm which employs a more efficient use of finite element mesh techniques and hence produces self-consistent and stable solutions for very short bunches. We investigate the fine structure of the CSR fields including coherent edge radiation. This approach should be useful in the study of existing and future concepts of particlemore » accelerators and ultrafast coherent light sources. The coherent synchrotron radiation (CSR) fields have a strong action on the beam dynamics of very short bunches, which are moving in the bends of all kinds of magnetic elements. They are responsible for additional energy loss and energy spread; micro bunching and beam emittance growth. These fields may bound the efficiency of damping rings, electron-positron colliders and ultrafast coherent light sources, where high peak currents and very short bunches are envisioned. This is relevant to most high-brightness beam applications. On the other hand these fields together with transition radiation fields can be used for beam diagnostics or even as a powerful resource of THz radiation. A history of the study of CSR and a good collection of references can be found in [1]. Electromagnetic theory suggests several methods on how to calculate CSR fields. The most popular method is to use Lienard-Wiechert potentials. Other approach is to solve numerically the approximate equations, which are a Schrodinger type equation. These numerical methods are described in [2]. We suggest that a direct solution of Maxwell's equations together with Newton's equations can describe the detailed structure of the CSR fields [3].« less

  19. Certified Professionals in Action

    EPA Pesticide Factsheets

    Irrigation professionals certified by WaterSense labeled certifying organizations are trained in water-efficient practices. Learn more about how professionals are helping customers save water with better irrigation practices.

  20. 26 CFR 1.302-4 - Termination of shareholder's interest.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ...) Avoidance of Federal income tax. Section 302(c)(2)(B) provides that section 302(c)(2)(A) shall not apply— (1... one of its principal purposes the avoidance of Federal income tax merely because the transferee is in... TAX (CONTINUED) INCOME TAXES Effects on Recipients § 1.302-4 Termination of shareholder's interest...

  1. [Design and validation of the CSR-Hospital-SP scale to measure corporate social responsibility].

    PubMed

    Mira, José Joaquín; Lorenzo, Susana; Navarro, Isabel; Pérez-Jover, Virtudes; Vitaller, Julián

    2013-01-01

    To design and validate a scale (CSR-Hospital-SP) to determine health professionals' views on the approach of management to corporate social responsibility (CSR) in their hospital. The literature was reviewed to identify the main CSR scales and select the dimensions to be evaluated. The initial version of the scale consisted of 25 items. A convenience sample of a minimum of 224 health professionals working in five public hospitals in five autonomous regions were invited to respond. Floor and ceiling effects, internal consistency, reliability, and construct validity were analyzed. A total of 233 health professionals responded. The CSR-Hospital-SP scale had 20 items grouped into four factors. The item-total correlation was higher than 0.30; all factor loadings were greater than 0.50; 59.57% of the variance was explained; Cronbach's alpha was 0.90; Spearman-Brown's coefficient was 0.82. The CSR-Hospital-SP scale is a tool designed for hospitals that implement accountability mechanisms and promote socially responsible management approaches. Copyright © 2012 SESPAS. Published by Elsevier Espana. All rights reserved.

  2. Global effects of the CSR-1 RNA interference pathway on the transcriptional landscape.

    PubMed

    Cecere, Germano; Hoersch, Sebastian; O'Keeffe, Sean; Sachidanandam, Ravi; Grishok, Alla

    2014-04-01

    Argonaute proteins and their small RNA cofactors short interfering RNAs are known to inhibit gene expression at the transcriptional and post-transcriptional levels. In Caenorhabditis elegans, the Argonaute CSR-1 binds thousands of endogenous siRNAs (endo-siRNAs) that are antisense to germline transcripts. However, its role in gene expression regulation remains controversial. Here we used genome-wide profiling of nascent RNA transcripts and found that the CSR-1 RNA interference pathway promoted sense-oriented RNA polymerase II transcription. Moreover, a loss of CSR-1 function resulted in global increase in antisense transcription and ectopic transcription of silent chromatin domains, which led to reduced chromatin incorporation of centromere-specific histone H3. On the basis of these findings, we propose that the CSR-1 pathway helps maintain the directionality of active transcription, thereby propagating the distinction between transcriptionally active and silent genomic regions.

  3. Protection of germline gene expression by the C. elegans Argonaute CSR-1.

    PubMed

    Wedeles, Christopher J; Wu, Monica Z; Claycomb, Julie M

    2013-12-23

    In Caenorhabditis elegans, the Piwi-interacting small RNA (piRNA)-mediated germline surveillance system encodes more than 30,000 unique 21-nucleotide piRNAs, which silence a variety of foreign nucleic acids. What mechanisms allow endogenous germline-expressed transcripts to evade silencing by the piRNA pathway? One likely candidate in a protective mechanism is the Argonaute CSR-1, which interacts with 22G-small RNAs that are antisense to nearly all germline-expressed genes. Here, we use an in vivo RNA tethering assay to demonstrate that the recruitment of CSR-1 to a transcript licenses expression of the transcript, protecting it from piRNA-mediated silencing. Licensing occurs mainly at the level of transcription, as we observe changes in pre-mRNA levels consistent with transcriptional activation when CSR-1 is tethered. Furthermore, the recruitment of CSR-1 to a previously silenced locus transcriptionally activates its expression. Together, these results demonstrate a rare positive role for an endogenous Argonaute pathway in heritably licensing and protecting germline transcripts.

  4. Difficulties of Alternatively Certified Teachers

    ERIC Educational Resources Information Center

    Schonfeld, Irvin Sam; Feinman, Samantha J.

    2012-01-01

    This daily diary study followed, over a 2-week period, 252 beginning New York City public school teachers. Seventy percent were alternatively certified (New York City Teaching Fellows) and the rest, traditionally certified teachers. Alternatively certified teachers were more likely to experience stressors such as violent incidents and classroom…

  5. Acute stress responses: A review and synthesis of ASD, ASR, and CSR.

    PubMed

    Isserlin, Leanna; Zerach, Gadi; Solomon, Zahava

    2008-10-01

    Toward the development of a unifying diagnosis for acute stress responses this article attempts to find a place for combat stress reaction (CSR) within the spectrum of other defined acute stress responses. This article critically compares the diagnostic criteria of acute stress disorder (ASD), acute stress reaction (ASR), and CSR. Prospective studies concerning the predictive value of ASD, ASR, and CSR are reviewed. Questions, recommendations, and implications for clinical practice are raised concerning the completeness of the current acute stress response diagnoses, the heterogeneity of different stressors, the scope of expected outcomes, and the importance of decline in function as an indicator of future psychological, psychiatric, and somatic distress. PsycINFO Database Record 2009 APA.

  6. How Do Internal and External CSR Affect Employees' Organizational Identification? A Perspective from the Group Engagement Model

    PubMed Central

    Hameed, Imran; Riaz, Zahid; Arain, Ghulam A.; Farooq, Omer

    2016-01-01

    The literature examines the impact of firms' corporate social responsibility (CSR) activities on employees' organizational identification without considering that such activities tend to have different targets. This study explores how perceived external CSR (efforts directed toward external stakeholders) and perceived internal CSR (efforts directed toward employees) activities influence employees' organizational identification. In so doing, it examines the alternative underlying mechanisms through which perceived external and internal CSR activities build employees' identification. Applying the taxonomy prescribed by the group engagement model, the study argues that the effects of perceived external and internal CSR flow through two competing mechanisms: perceived external prestige and perceived internal respect, respectively. Further, it is suggested that calling orientation (how employees see their work contributions) moderates the effects induced by these alternative forms of CSR. The model draws on survey data collected from a sample of 414 employees across five large multinationals in Pakistan. The results obtained using structural equation modeling support these hypotheses, reinforcing the notion that internal and external CSR operate through different mediating mechanisms and more interestingly employees' calling orientation moderates these relationships to a significant degree. Theoretical contributions and practical implications of results are discussed in detail. PMID:27303345

  7. How Do Internal and External CSR Affect Employees' Organizational Identification? A Perspective from the Group Engagement Model.

    PubMed

    Hameed, Imran; Riaz, Zahid; Arain, Ghulam A; Farooq, Omer

    2016-01-01

    The literature examines the impact of firms' corporate social responsibility (CSR) activities on employees' organizational identification without considering that such activities tend to have different targets. This study explores how perceived external CSR (efforts directed toward external stakeholders) and perceived internal CSR (efforts directed toward employees) activities influence employees' organizational identification. In so doing, it examines the alternative underlying mechanisms through which perceived external and internal CSR activities build employees' identification. Applying the taxonomy prescribed by the group engagement model, the study argues that the effects of perceived external and internal CSR flow through two competing mechanisms: perceived external prestige and perceived internal respect, respectively. Further, it is suggested that calling orientation (how employees see their work contributions) moderates the effects induced by these alternative forms of CSR. The model draws on survey data collected from a sample of 414 employees across five large multinationals in Pakistan. The results obtained using structural equation modeling support these hypotheses, reinforcing the notion that internal and external CSR operate through different mediating mechanisms and more interestingly employees' calling orientation moderates these relationships to a significant degree. Theoretical contributions and practical implications of results are discussed in detail.

  8. CDE-1 affects chromosome segregation through uridylation of CSR-1-bound siRNAs.

    PubMed

    van Wolfswinkel, Josien C; Claycomb, Julie M; Batista, Pedro J; Mello, Craig C; Berezikov, Eugene; Ketting, René F

    2009-10-02

    We have studied the function of a conserved germline-specific nucleotidyltransferase protein, CDE-1, in RNAi and chromosome segregation in C. elegans. CDE-1 localizes specifically to mitotic chromosomes in embryos. This localization requires the RdRP EGO-1, which physically interacts with CDE-1, and the Argonaute protein CSR-1. We found that CDE-1 is required for the uridylation of CSR-1 bound siRNAs, and that in the absence of CDE-1 these siRNAs accumulate to inappropriate levels, accompanied by defects in both meiotic and mitotic chromosome segregation. Elevated siRNA levels are associated with erroneous gene silencing, most likely through the inappropriate loading of CSR-1 siRNAs into other Argonaute proteins. We propose a model in which CDE-1 restricts specific EGO-1-generated siRNAs to the CSR-1 mediated, chromosome associated RNAi pathway, thus separating it from other endogenous RNAi pathways. The conserved nature of CDE-1 suggests that similar sorting mechanisms may operate in other animals, including mammals.

  9. The Csr System Regulates Escherichia coli Fitness by Controlling Glycogen Accumulation and Energy Levels.

    PubMed

    Morin, Manon; Ropers, Delphine; Cinquemani, Eugenio; Portais, Jean-Charles; Enjalbert, Brice; Cocaign-Bousquet, Muriel

    2017-10-31

    In the bacterium Escherichia coli , the posttranscriptional regulatory system Csr was postulated to influence the transition from glycolysis to gluconeogenesis. Here, we explored the role of the Csr system in the glucose-acetate transition as a model of the glycolysis-to-gluconeogenesis switch. Mutations in the Csr system influence the reorganization of gene expression after glucose exhaustion and disturb the timing of acetate reconsumption after glucose exhaustion. Analysis of metabolite concentrations during the transition revealed that the Csr system has a major effect on the energy levels of the cells after glucose exhaustion. This influence was demonstrated to result directly from the effect of the Csr system on glycogen accumulation. Mutation in glycogen metabolism was also demonstrated to hinder metabolic adaptation after glucose exhaustion because of insufficient energy. This work explains how the Csr system influences E. coli fitness during the glycolysis-gluconeogenesis switch and demonstrates the role of glycogen in maintenance of the energy charge during metabolic adaptation. IMPORTANCE Glycogen is a polysaccharide and the main storage form of glucose from bacteria such as Escherichia coli to yeasts and mammals. Although its function as a sugar reserve in mammals is well documented, the role of glycogen in bacteria is not as clear. By studying the role of posttranscriptional regulation during metabolic adaptation, for the first time, we demonstrate the role of sugar reserve played by glycogen in E. coli Indeed, glycogen not only makes it possible to maintain sufficient energy during metabolic transitions but is also the key component in the capacity of cells to resume growth. Since the essential posttranscriptional regulatory system Csr is a major regulator of glycogen accumulation, this work also sheds light on the central role of posttranscriptional regulation in metabolic adaptation. Copyright © 2017 Morin et al.

  10. 26 CFR 1.6035-1 - Returns of U.S. officers, directors and 10-percent shareholders of foreign personal holding...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., directors and 10-percent shareholders of foreign personal holding companies for taxable years beginning... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Returns of U.S. officers, directors and 10-percent shareholders of foreign personal holding companies for taxable years beginning after September 3...

  11. 26 CFR 1.6035-1 - Returns of U.S. officers, directors and 10-percent shareholders of foreign personal holding...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    .... officers, directors and 10-percent shareholders of foreign personal holding companies for taxable years... 26 Internal Revenue 13 2011-04-01 2011-04-01 false Returns of U.S. officers, directors and 10-percent shareholders of foreign personal holding companies for taxable years beginning after September 3...

  12. An experimental test of CSR theory using a globally calibrated ordination method

    PubMed Central

    Li, Yuanzhi

    2017-01-01

    Can CSR theory, in conjunction with a recently proposed globally calibrated CSR ordination (“StrateFy”), using only three easily measured leaf traits (leaf area, specific leaf area and leaf dry matter content) predict the functional signature of herbaceous vegetation along experimentally manipulated gradients of soil fertility and disturbance? To determine this, we grew 37 herbaceous species in mixture for five years in 24 experimental mesocosms differing in factorial levels of soil resources (stress) and density-independent mortality (disturbance). We measured 16 different functional traits and then ordinated the resulting vegetation within the CSR triangle using StrateFy. We then calculated community-weighted mean (CWM) values of the competitor (CCWM), stress-tolerator (SCWM) and ruderal (RCWM) scores for each mesocosm. We found a significant increase in SCWM from low to high stress mesocosms, and an increase in RCWM from lowly to highly disturbed mesocosms. However, CCWM did not decline significantly as intensity of stress or disturbance increased, as predicted by CSR theory. This last result likely arose because our herbaceous species were relatively poor competitors in global comparisons and thus no strong competitors in our species pool were selectively favoured in low stress and low disturbed mesocosms. Variation in the 13 other traits, not used by StrateFy, largely argeed with the predictions of CSR theory. StrateFy worked surprisingly well in our experimental study except for the C-dimension. Despite loss of some precision, it has great potential applicability in future studies due to its simplicity and generality. PMID:28388622

  13. An experimental test of CSR theory using a globally calibrated ordination method.

    PubMed

    Li, Yuanzhi; Shipley, Bill

    2017-01-01

    Can CSR theory, in conjunction with a recently proposed globally calibrated CSR ordination ("StrateFy"), using only three easily measured leaf traits (leaf area, specific leaf area and leaf dry matter content) predict the functional signature of herbaceous vegetation along experimentally manipulated gradients of soil fertility and disturbance? To determine this, we grew 37 herbaceous species in mixture for five years in 24 experimental mesocosms differing in factorial levels of soil resources (stress) and density-independent mortality (disturbance). We measured 16 different functional traits and then ordinated the resulting vegetation within the CSR triangle using StrateFy. We then calculated community-weighted mean (CWM) values of the competitor (CCWM), stress-tolerator (SCWM) and ruderal (RCWM) scores for each mesocosm. We found a significant increase in SCWM from low to high stress mesocosms, and an increase in RCWM from lowly to highly disturbed mesocosms. However, CCWM did not decline significantly as intensity of stress or disturbance increased, as predicted by CSR theory. This last result likely arose because our herbaceous species were relatively poor competitors in global comparisons and thus no strong competitors in our species pool were selectively favoured in low stress and low disturbed mesocosms. Variation in the 13 other traits, not used by StrateFy, largely argeed with the predictions of CSR theory. StrateFy worked surprisingly well in our experimental study except for the C-dimension. Despite loss of some precision, it has great potential applicability in future studies due to its simplicity and generality.

  14. Orientation of Agri-Food Companies to CSR And Consumer Perception: A Survey on Two Italian Companies.

    PubMed

    Civero, Gennaro; Rusciano, Vincenzo; Scarpato, Debora

    2018-05-07

    Corporate Social Responsibility (CSR) is the most important tool for implementing Sustainability Guidelines for Business (US20030018487A1), delivering economic, social and environmental benefits for all the stakeholders and is currently the focus of international studies and debates (US7260559B1), especially in the agri-food sector as demonstrated by recent patents (CA2862273A1). In most agri-food businesses operating in Italy, there is little effectiveness in the communication strategies of this instrument to the stakeholders since they are often not advanced. Identifying the first two food companies in the European ranking of the 6th CSR Online Awards, through an empirical survey on consumers, their level of perception of the CSR strategies communication of this companies will be analyzed. In both case studies analyzed, there is the presence of a Sustainability Orientation and the evolution of CSR tools within such companies and their promotion and communication to all the stakeholders. Despite this, the level of perception of respondents on the CSR strategies communication of this companies and the promotion of CSR instruments is not optimal. The interviewed consumers has not enriched its knowledge on CSR due to the lack of an adequate communication strategy for both case studies. Consequently, to raise awareness on the subject, there is still a great deal of cooperation needed between public institutions, local communities, businesses and citizens. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  15. A Csr-type regulatory system, including small non-coding RNAs, regulates the global virulence regulator RovA of Yersinia pseudotuberculosis through RovM.

    PubMed

    Heroven, Ann Kathrin; Böhme, Katja; Rohde, Manfred; Dersch, Petra

    2008-06-01

    The MarR-type regulator RovA controls expression of virulence genes of Yersinia pseudotuberculosis in response to environmental signals. Using a genetic strategy to discover components that influence rovA expression, we identified new regulatory factors with homology to components of the carbon storage regulator system (Csr). We showed that overexpression of a CsrB- or a CsrC-type RNA activates rovA, whereas a CsrA-like protein represses RovA synthesis. We further demonstrate that influence of the Csr system on rovA is indirect and occurs through control of the LysR regulator RovM, which inhibits rovA transcription. The CsrA protein had also a major influence on the motility of Yersinia, which was independent of RovM. The CsrB and CsrC RNAs are differentially expressed in Yersinia. CsrC is highly induced in complex but not in minimal media, indicating that medium-dependent rovM expression is mediated through CsrC. CsrB synthesis is generally very low. However, overexpression of the response regulator UvrY was found to activate CsrB production, which in turn represses CsrC synthesis independent of the growth medium. In summary, the post-transcriptional Csr-type components were shown to be key regulators in the co-ordinated environmental control of physiological processes and virulence factors, which are crucial for the initiation of Yersinia infections.

  16. A Comparison of Retention Rates of Alternatively Certified and Traditional Certified Teachers.

    ERIC Educational Resources Information Center

    Dial, Micah

    1992-01-01

    A survey of 2,500 teachers entering a large urban school district over the last 7 years showed that alternatively certified teachers were as likely as traditional, university-certified teachers to remain in the profession and pay back the school district's initial investment in teacher training. Many become committed to teaching as a meaningful…

  17. 12 CFR 327.2 - Certified statements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... ASSESSMENTS In General § 327.2 Certified statements. (a) Required. (1) The certified statement shall also be...) The quarterly certified statement invoice shall reflect the institution's risk assignment, assessment base, assessment computation, and assessment amount, for each quarterly assessment period. (b...

  18. 7 CFR 1221.4 - Certified organization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 10 2010-01-01 2010-01-01 false Certified organization. 1221.4 Section 1221.4 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING... organization. Certified organization means any organization that has been certified by the Secretary pursuant...

  19. The Culture of Corporate Social Responsibility (CSR) in the Academic Framework: Some Literary Implications

    ERIC Educational Resources Information Center

    Mehta, Sandhya Rao

    2011-01-01

    Corporate Social Responsibility (CSR) is swiftly emerging as an integral part of corporate culture and discourse. Associated with notions of responsibility, accountability and community involvement, it remains privileged with concerns that increasingly define the new millennium. Less developed, however, is the relevance of CSR ideas to academic…

  20. 7 CFR 945.7 - Certified seed potatoes.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Certified seed potatoes. 945.7 Section 945.7... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN CERTAIN... Certified seed potatoes. Certified seed potatoes means and includes all potatoes officially certified and...

  1. 7 CFR 945.7 - Certified seed potatoes.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 8 2011-01-01 2011-01-01 false Certified seed potatoes. 945.7 Section 945.7... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN CERTAIN... Certified seed potatoes. Certified seed potatoes means and includes all potatoes officially certified and...

  2. 7 CFR 945.7 - Certified seed potatoes.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 8 2013-01-01 2013-01-01 false Certified seed potatoes. 945.7 Section 945.7... AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN CERTAIN... Certified seed potatoes. Certified seed potatoes means and includes all potatoes officially certified and...

  3. 7 CFR 945.7 - Certified seed potatoes.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 8 2014-01-01 2014-01-01 false Certified seed potatoes. 945.7 Section 945.7... AGREEMENTS AND ORDERS; FRUITS, VEGETABLES, NUTS), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN CERTAIN... Certified seed potatoes. Certified seed potatoes means and includes all potatoes officially certified and...

  4. 7 CFR 945.7 - Certified seed potatoes.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 8 2012-01-01 2012-01-01 false Certified seed potatoes. 945.7 Section 945.7... Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE IRISH POTATOES GROWN IN CERTAIN... Certified seed potatoes. Certified seed potatoes means and includes all potatoes officially certified and...

  5. 40 CFR 158.350 - Certified limits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Certified limits. 158.350 Section 158.350 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.350 Certified limits. The applicant must propose certified...

  6. 40 CFR 158.350 - Certified limits.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 24 2014-07-01 2014-07-01 false Certified limits. 158.350 Section 158.350 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.350 Certified limits. The applicant must propose certified...

  7. 40 CFR 158.350 - Certified limits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Certified limits. 158.350 Section 158.350 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.350 Certified limits. The applicant must propose certified...

  8. 40 CFR 158.350 - Certified limits.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 25 2012-07-01 2012-07-01 false Certified limits. 158.350 Section 158.350 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.350 Certified limits. The applicant must propose certified...

  9. 40 CFR 158.350 - Certified limits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Certified limits. 158.350 Section 158.350 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR PESTICIDES Product Chemistry § 158.350 Certified limits. The applicant must propose certified...

  10. Biofilm Formation and Dispersal under the Influence of the Global Regulator CsrA of Escherichia coli

    PubMed Central

    Jackson, Debra W.; Suzuki, Kazushi; Oakford, Lawrence; Simecka, Jerry W.; Hart, Mark E.; Romeo, Tony

    2002-01-01

    The predominant mode of growth of bacteria in the environment is within sessile, matrix-enclosed communities known as biofilms. Biofilms often complicate chronic and difficult-to-treat infections by protecting bacteria from the immune system, decreasing antibiotic efficacy, and dispersing planktonic cells to distant body sites. While the biology of bacterial biofilms has become a major focus of microbial research, the regulatory mechanisms of biofilm development remain poorly defined and those of dispersal are unknown. Here we establish that the RNA binding global regulatory protein CsrA (carbon storage regulator) of Escherichia coli K-12 serves as both a repressor of biofilm formation and an activator of biofilm dispersal under a variety of culture conditions. Ectopic expression of the E. coli K-12 csrA gene repressed biofilm formation by related bacterial pathogens. A csrA knockout mutation enhanced biofilm formation in E. coli strains that were defective for extracellular, surface, or regulatory factors previously implicated in biofilm formation. In contrast, this csrA mutation did not affect biofilm formation by a glgA (glycogen synthase) knockout mutant. Complementation studies with glg genes provided further genetic evidence that the effects of CsrA on biofilm formation are mediated largely through the regulation of intracellular glycogen biosynthesis and catabolism. Finally, the expression of a chromosomally encoded csrA′-′lacZ translational fusion was dynamically regulated during biofilm formation in a pattern consistent with its role as a repressor. We propose that global regulation of central carbon flux by CsrA is an extremely important feature of E. coli biofilm development. PMID:11741870

  11. Complex regulatory network encompassing the Csr, c-di-GMP and motility systems of Salmonella Typhimurium.

    PubMed

    Jonas, Kristina; Edwards, Adrianne N; Ahmad, Irfan; Romeo, Tony; Römling, Ute; Melefors, Ojar

    2010-02-01

    Bacterial survival depends on the ability to switch between sessile and motile lifestyles in response to changing environmental conditions. In many species, this switch is governed by (3'-5')-cyclic-diguanosine monophosphate (c-di-GMP), a signalling molecule, which is metabolized by proteins containing GGDEF and/or EAL domains. Salmonella Typhimurium contains 20 such proteins. Here, we show that the RNA-binding protein CsrA regulates the expression of eight genes encoding GGDEF, GGDEF-EAL and EAL domain proteins. CsrA bound directly to the mRNA leaders of five of these genes, suggesting that it may regulate these genes post-transcriptionally. The c-di-GMP-specific phosphodiesterase STM3611, which reciprocally controls flagella function and production of biofilm matrix components, was regulated by CsrA binding to the mRNA, but was also indirectly regulated by CsrA through the FlhDC/FliA flagella cascade and STM1344. STM1344 is an unconventional (c-di-GMP-inactive) EAL domain protein, recently identified as a negative regulator of flagella gene expression. Here, we demonstrate that CsrA directly downregulates expression of STM1344, which in turn regulates STM3611 through fliA and thus reciprocally controls motility and biofilm factors. Altogether, our data reveal that the concerted and complex regulation of several genes encoding GGDEF/EAL domain proteins allows CsrA to control the motility-sessility switch in S. Typhimurium at multiple levels.

  12. 7 CFR 983.7 - Certified pistachios.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 8 2010-01-01 2010-01-01 false Certified pistachios. 983.7 Section 983.7 Agriculture... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE PISTACHIOS GROWN IN CALIFORNIA, ARIZONA, AND NEW MEXICO Definitions § 983.7 Certified pistachios. Certified pistachios are those that meet...

  13. 12 CFR 327.2 - Certified statements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... that, to the best of his or her knowledge and belief, the information shown on the quarterly certified... belief, the information shown on the quarterly certified statement invoice is not true, correct, and... quarterly certified statement invoice under paragraph (e)(2), that will result in a change to deposit...

  14. Prospects for searching the η→e+e- rare decay at the CSR

    NASA Astrophysics Data System (ADS)

    Ji, Chang-Sheng; Shao, Ming; Zhang, Hui; Chen, Hong-Fang; Zhang, Yi-Fei

    2013-04-01

    We study the possibility of searching the η→e+e- rare decay on the Cooling Storage Ring (CSR) at Lanzhou. The main features of the proposed Internal Target Experiment (ITE) and External Target Facility (ETF) are included in the Monte Carlo simulation. Both the beam condition at the CSR and the major physics backgrounds are carefully taken into account. We conclude that the ITE is more suitable for such a study due to better detector acceptance and higher beam density. At the maximum designed luminosity (1034 cm-2 s-1), η→e+e- events can be collected every ~400 seconds at the CSR. With a mass resolution of 1 MeV, the expected signal-to-background (S/B) ratio is around 1.

  15. Teacher quality: a comparison of National Board-certified and non-Board-certified teachers of deaf students.

    PubMed

    Scheetz, Nanci A; Martin, David S

    2006-01-01

    THE STUDY was designed to identify specific components of teacher excellence, focusing initially on the characteristics of the small number of teachers of the deaf who are certified by the National Board for Professional Teaching Standards (NBPTS), then comparing those with the characteristics of other teachers identified as master teachers by university faculty in teacher preparation in deafness. Classroom observation, written lesson plans, teacher questionnaires on beliefs, and content analysis of interactive electronic focus groups were used to compare the two groups of teachers. Results indicated similarities between Board-certified and non-Board-certified master teachers in regard to teacher behaviors and commitment to well-founded pedagogical principles. Differences were found in classroom priorities and in the greater level of interconnectivity expressed by Board-certified teachers as the result of becoming Board certified. Recommendations are made for preparing teachers of deaf students.

  16. How the Process of the CSR Activities Works on Private Hospitals and Pharmaceutical Firms: Multiple Case Study from Strategic Perspective.

    PubMed

    Yıldırım, Mustafa; Dinçer, Mustafa Abdül Metin

    2018-06-23

    The phenomenon of corporate social responsibility "CSR" has stimulated lots of debates and disagreement among the business scholars. One of the most howling sounds comes from strategy and CSR thinkers. Strategic thinkers of this debate believe that CSR is not only an accountability action but also it is countability action. Due to this countability action heavily based on profit, the scholar of strategy field stated that strategic thinking lens should revise the phenomenon of CSR and the result of its activities. To this end in this study, we examine the CSR activities, especially philanthropy activities (sports, art sponsorships, etc.) from strategy perspectives. And the question of this study is "How the process of the CSR activities work on private hospitals and pharmaceutical firms?" In this framework, private hospitals, pharmaceutical firms in Turkey, and their CSR activity and global compact reports are used as the cases of the study. We make qualitative content analysis, and the documents in this study are analyzed with qualitative analysis software (MAXQDA). The results which were obtained from the analysis are considered important by the researchers since it is shown in this multiple case study that private hospitals and pharmaceutical firms have to focus on some specific points in their social responsibility activities to get competitive superiority for themselves and gain profit in the long term. While the CSR orientation of the private hospitals concentrates on sports dimension, the direction of pharmaceutical firms is on education dimension. In both fields, the cases construct their CSR activities on these two dimensions or relate their other CSR activities with these dimensions.

  17. The RNA binding protein CsrA controls c-di-GMP metabolism by directly regulating the expression of GGDEF proteins

    PubMed Central

    Jonas, Kristina; Edwards, Adrianne N.; Simm, Roger; Romeo, Tony; Römling, Ute; Melefors, Öjar

    2009-01-01

    Summary The carbon storage regulator CsrA is an RNA binding protein that controls carbon metabolism, biofilm formation and motility in various eubacteria. Nevertheless, in Escherichia coli only five target mRNAs have been shown to be directly regulated by CsrA at the post-transcriptional level. Here we identified two new direct targets for CsrA, ycdT and ydeH, both of which encode proteins with GGDEF domains. A csrA mutation caused mRNA levels of ycdT and ydeH to increase more than 10-fold. RNA mobility shift assays confirmed the direct and specific binding of CsrA to the mRNA leaders of ydeH and ycdT. Overexpression of ycdT and ydeH resulted in a more than 20-fold increase in the cellular concentration of the second messenger c-di-GMP, implying that both proteins possess diguanylate cyclase activity. Phenotypic characterization revealed that both proteins are involved in the regulation of motility in a c-di-GMP dependent manner. CsrA was also found to regulate the expression of five additional GGDEF/EAL proteins and a csrA mutation led to modestly increased cellular levels of c-di-GMP. All together, these data demonstrate a global role for CsrA in the regulation of c-di-GMP metabolism by regulating the expression of GGDEF proteins at the post-transcriptional level. PMID:18713317

  18. Norwegian farmers ceasing certified organic production: characteristics and reasons.

    PubMed

    Flaten, Ola; Lien, Gudbrand; Koesling, Matthias; Løes, Anne-Kristin

    2010-12-01

    This article examines the characteristics of and reasons for Norwegian farmers' ceasing or planning to cease certified organic production. We gathered cross-sectional survey data in late 2007 from organic farmers deregistering between January 2004 and September 2007 (n=220), and similar data from a random sample of farmers with certified organic management in 2006 (n=407). Of the respondents deregistering by November 2007, 17% had quit farming altogether, 61% now farmed conventionally, and 21% were still farming by organic principles, but without certification. Nearly one in four organic farmers in 2007 indicated that they planned to cease certification within the next 5-10 years. From the two survey samples, we categorised farmers who expect to be deregistered in 5-10 years into three groups: conventional practices (n=139), continuing to farm using organic principles (uncertified organic deregistrants, n=105), and stopped farming (n=33). Of the numerous differences among these groups, two were most striking: the superior sales of uncertified organic deregistrants through consumer-direct marketing and the lowest shares of organic land among conventional deregistrants. We summarised a large number of reasons for deregistering into five factors through factor analysis: economics, regulations, knowledge-exchange, production, and market access. Items relating to economics and regulations were the primary reasons offered for opting out. The regression analysis showed that the various factors were associated with several explanatory variables. Regulations, for example, figured more highly among livestock farmers than crop farmers. The economic factor strongly reflected just a few years of organic management. Policy recommendations for reducing the number of dropouts are to focus on economics, environmental attitudes, and the regulatory issues surrounding certified organic production. Copyright © 2010 Elsevier Ltd. All rights reserved.

  19. 30 CFR 77.100 - Certified person.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Certified person. 77.100 Section 77.100 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY SAFETY STANDARDS, SURFACE COAL MINES AND SURFACE WORK AREAS OF UNDERGROUND COAL MINES Qualified and Certified Persons § 77.100 Certified...

  20. Buy Certified-Verified Green Power

    EPA Pesticide Factsheets

    Green power products eligible to be certified by an independent third party against national standards. As a matter of best practice and consumer protection, EPA strongly encourages organizations to purchase these types of certified green power products.

  1. 48 CFR 15.403-5 - Instructions for submission of certified cost or pricing data and data other than certified cost...

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... submission of certified cost or pricing data and data other than certified cost or pricing data. 15.403-5... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.403-5 Instructions for submission of certified cost or pricing data and data other than certified cost or pricing data. (a) Taking into...

  2. 48 CFR 15.403-5 - Instructions for submission of certified cost or pricing data and data other than certified cost...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... submission of certified cost or pricing data and data other than certified cost or pricing data. 15.403-5... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.403-5 Instructions for submission of certified cost or pricing data and data other than certified cost or pricing data. (a) Taking into...

  3. 48 CFR 15.403-5 - Instructions for submission of certified cost or pricing data and data other than certified cost...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... submission of certified cost or pricing data and data other than certified cost or pricing data. 15.403-5... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.403-5 Instructions for submission of certified cost or pricing data and data other than certified cost or pricing data. (a) Taking into...

  4. 48 CFR 15.403-5 - Instructions for submission of certified cost or pricing data and data other than certified cost...

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... submission of certified cost or pricing data and data other than certified cost or pricing data. 15.403-5... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.403-5 Instructions for submission of certified cost or pricing data and data other than certified cost or pricing data. (a) Taking into...

  5. 48 CFR 15.403-5 - Instructions for submission of certified cost or pricing data and data other than certified cost...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... submission of certified cost or pricing data and data other than certified cost or pricing data. 15.403-5... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Contract Pricing 15.403-5 Instructions for submission of certified cost or pricing data and data other than certified cost or pricing data. (a) Taking into...

  6. Certified records manager exam

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1990-01-01

    The Institute of Certified Records Managers (ICRM) is a non-profit, certifying organization of professional records managers and administrators. ICRM members are experienced in information requirements, records and information systems, and the related office systems and technologies. All members have met certification requirements and have received the Certified Records Manager (CRM) designation. As the field of information and records management moves toward standardization, and as the application of new technologies and technicalities complicate the measurement and demonstration of professional competence, the need for a means of identifying persons who have basic competency increases. The ICRM is providing such a means bymore » testing and certifying basic knowledge. More and more job announcements are requiring this evidence of competency. Unfortunately, as an organization, NIRMA has a relatively small number of CRMs. The goal of the ICRM Development Group is two-fold; (1) to encourage NIRMA members to obtain their certification by providing basic information and support and; (2) to develop the Nuclear Specialist test module which will demonstrate that bearers have demonstrated expertise in nuclear records management as well as basic competencies. This report covers the examination process.« less

  7. A Comparison of the Ethical Beliefs of Certified Rehabilitation Counselors and National Certified Counselors

    ERIC Educational Resources Information Center

    Tarvydas, V. M.; Leahy, M. J.; Saunders, J. L.

    2004-01-01

    Results of a national survey of certified rehabilitation counselors (CRCs) are compared with those obtained by Gibson and Pope (1993) from a national sample of national certified counselors (NCCs) to determine their beliefs about whether particular behaviors are ethical, and the degree of consensus or controversy about these behaviors.…

  8. 26 CFR 1.1291-1 - Taxation of U.S. persons that are shareholders of PFICs that are not pedigreed QEFs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Taxation of U.S. persons that are shareholders of PFICs that are not pedigreed QEFs. 1.1291-1 Section 1.1291-1 Internal Revenue INTERNAL REVENUE... Determining Capital Gains and Losses § 1.1291-1 Taxation of U.S. persons that are shareholders of PFICs that...

  9. 26 CFR 1.1291-1 - Taxation of U.S. persons that are shareholders of PFICs that are not pedigreed QEFs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Taxation of U.S. persons that are shareholders of PFICs that are not pedigreed QEFs. 1.1291-1 Section 1.1291-1 Internal Revenue INTERNAL REVENUE... Rules for Determining Capital Gains and Losses § 1.1291-1 Taxation of U.S. persons that are shareholders...

  10. Reduced expression of the global regulator protein CsrA in Legionella pneumophila affects virulence-associated regulators and growth in Acanthamoeba castellanii.

    PubMed

    Forsbach-Birk, Vera; McNealy, Tamara; Shi, Chunwei; Lynch, Damien; Marre, Reinhard

    2004-07-01

    Legionella bacteria have a developmental cycle in which they go from existing in the aquatic environment to replicating inside eukaryotic host cells. The adaptation to the new environment requires an efficient regulatory system. Overexpression of CsrA, a global regulatory protein found in a variety of gram-negative bacteria has been shown to suppress virulence-associated traits in Legionella pneumophila. Since evidence resulting only from overproduction may not be sufficient to validate the role of a regulatory protein, a csrA mutant strain, CsrA(-), with a drastically reduced production of CsrA, was created. Using RNA slot blots and Western blotting it was shown that fliA and flaA, genes which contribute to flagellation, were expressed early in the mutant. Additionally, in CsrA(-) the levels of the stationary-phase sigma factor, RpoS, and a recently described regulator of virulence traits, LetE, were increased. Growth curves of CsrA(-) bacteria were delayed with pigment production occurring at the same OD578 but at reduced levels in the mutant. Replication ability of the CsrA(-) mutant in amoebae was also affected. Based on these results, we could show that CsrA is involved in the regulation of the bacterial switch from the replicative to the transmissible form.

  11. 26 CFR 1.995-1 - Taxation of DISC income to shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 26 Internal Revenue 10 2010-04-01 2010-04-01 false Taxation of DISC income to shareholders. 1.995...) INCOME TAX (CONTINUED) INCOME TAXES Domestic International Sales Corporations § 1.995-1 Taxation of DISC... to taxation on the earnings and profits of the DISC in accordance with the provisions of chapter 1 of...

  12. 45 CFR 155.225 - Certified application counselors.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... agency, to certify its staff members or volunteers to act as certified application counselors who perform...) of this section; (ii) Directly certifying individual staff members or volunteers of Exchange... or volunteer enters into an agreement with the Exchange to comply with the standards and requirements...

  13. Closing the Achievement Gap: Urban Schools. CSR Connection.

    ERIC Educational Resources Information Center

    Porter, Kathleen; Soper, Stephanie

    This report reviews efforts to reform urban schools, focusing on initiatives in Tennessee and California as examples from which distric leaders may draw useful lessons. The report suggests that comprehensive school reform (CSR) offers promise to struggling urban schools by focusing on transforming the academic climate, school culture, and…

  14. 7 CFR 201.69 - Classes of certified seed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Classes of certified seed. 201.69 Section 201.69..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.69 Classes of certified seed. (a) Classes of certified seed are as follows...

  15. 7 CFR 201.69 - Classes of certified seed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Classes of certified seed. 201.69 Section 201.69..., Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.69 Classes of certified seed. (a) Classes of certified seed are as follows...

  16. 26 CFR 1.852-7 - Additional information required in returns of shareholders.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.852-7 Additional information required in returns of shareholders. Any person who fails or refuses to comply with the demand of a regulated investment company for the written statements...

  17. 26 CFR 1.852-7 - Additional information required in returns of shareholders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.852-7 Additional information required in returns of shareholders. Any person who fails or refuses to comply with the demand of a regulated investment company for the written statements...

  18. 26 CFR 1.852-7 - Additional information required in returns of shareholders.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.852-7 Additional information required in returns of shareholders. Any person who fails or refuses to comply with the demand of a regulated investment company for the written statements...

  19. 26 CFR 1.852-7 - Additional information required in returns of shareholders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.852-7 Additional information required in returns of shareholders. Any person who fails or refuses to comply with the demand of a regulated investment company for the written statements...

  20. Status and Assessments of CSR GRACE Level-2 Data Products

    NASA Astrophysics Data System (ADS)

    Bettadpur, Srinivas; Kang, Zhigui; Nagel, Peter; Pastor, Rick; Poole, Steve; Ries, John; Save, Himanshu

    2015-04-01

    The joint NASA/DLR GRACE mission has successfully operated for more than 13 years, and has provided a remarkable record of global mass flux due to a large variety of geophysical and climate processes at various spatio-temporal scales. The University of Texas Center for Space Research (CSR) hosts the mission PI, and is responsible for delivery of operational (presently denoted as Release-05 or RL05) gravity field data products. In addition, CSR generates and distributes a variety of other gravity field data products, including products generated from the use of satellite laser ranging data. This poster will provide an overview of all these data products, their relative quality, potential applications, and future plans for their development and delivery.

  1. The Argonaute CSR-1 and its 22G-RNA cofactors are required for holocentric chromosome segregation.

    PubMed

    Claycomb, Julie M; Batista, Pedro J; Pang, Ka Ming; Gu, Weifeng; Vasale, Jessica J; van Wolfswinkel, Josien C; Chaves, Daniel A; Shirayama, Masaki; Mitani, Shohei; Ketting, René F; Conte, Darryl; Mello, Craig C

    2009-10-02

    RNAi-related pathways regulate diverse processes, from developmental timing to transposon silencing. Here, we show that in C. elegans the Argonaute CSR-1, the RNA-dependent RNA polymerase EGO-1, the Dicer-related helicase DRH-3, and the Tudor-domain protein EKL-1 localize to chromosomes and are required for proper chromosome segregation. In the absence of these factors chromosomes fail to align at the metaphase plate and kinetochores do not orient to opposing spindle poles. Surprisingly, the CSR-1-interacting small RNAs (22G-RNAs) are antisense to thousands of germline-expressed protein-coding genes. Nematodes assemble holocentric chromosomes in which continuous kinetochores must span the expressed domains of the genome. We show that CSR-1 interacts with chromatin at target loci but does not downregulate target mRNA or protein levels. Instead, our findings support a model in which CSR-1 complexes target protein-coding domains to promote their proper organization within the holocentric chromosomes of C. elegans.

  2. 30 CFR 70.202 - Certified person; sampling.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Certified person; sampling. 70.202 Section 70... HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Sampling Procedures § 70.202 Certified person; sampling. (a) The respirable dust sampling required by this part shall be done by a certified person. (b...

  3. 30 CFR 70.202 - Certified person; sampling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Certified person; sampling. 70.202 Section 70... HEALTH MANDATORY HEALTH STANDARDS-UNDERGROUND COAL MINES Sampling Procedures § 70.202 Certified person; sampling. (a) The respirable dust sampling required by this part shall be done by a certified person. (b...

  4. Effects of Core-Shell Rubber (CSR) Nanoparticles on the Fracture Toughness of an Epoxy Resin at Cryogenic Temperatures

    NASA Technical Reports Server (NTRS)

    Wang, J.; Cannon, S. A.; Schneider, J. A.

    2008-01-01

    This study investigates the effects of core-shell rubber (CSR) nanoparticles on the fracture toughness of an epoxy resin at liquid nitrogen (LN2) temperatures. Varying amounts of Kane Ace (Registered TradeMark) MX130 toughening agent were added to a commercially available EPON 862/W epoxy resin. Resulting fracture toughness was evaluated by the use of Charpy impact tests conducted on an instrumented drop tower. The size and distribution of the CSR nanoparticles were characterized using Transmission Electric Microscopy (TEM) and Small Angle X-ray Scattering (SAXS). Up to nominal 4.6% addition of the CSR nanoparticles, resulted in a nearly 5 times increase in the measured breaking energy. However, further increases in the amount of CSR nanoparticles had no appreciable affect on the breaking energy.

  5. 30 CFR 90.202 - Certified person; sampling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Certified person; sampling. 90.202 Section 90... Sampling Procedures § 90.202 Certified person; sampling. (a) The respirable dust sampling required by this... on sampling of respirable coal mine dust. (c) A person may be temporarily certified by MSHA to take...

  6. 30 CFR 71.202 - Certified person; sampling.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Certified person; sampling. 71.202 Section 71... Sampling Procedures § 71.202 Certified person; sampling. (a) The respirable dust sampling required by this... on sampling of respirable coal mine dust. (c) A person may be temporarily certified by MSHA to take...

  7. 30 CFR 71.202 - Certified person; sampling.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Certified person; sampling. 71.202 Section 71... Sampling Procedures § 71.202 Certified person; sampling. (a) The respirable dust sampling required by this... on sampling of respirable coal mine dust. (c) A person may be temporarily certified by MSHA to take...

  8. 30 CFR 90.202 - Certified person; sampling.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Certified person; sampling. 90.202 Section 90... Sampling Procedures § 90.202 Certified person; sampling. (a) The respirable dust sampling required by this... on sampling of respirable coal mine dust. (c) A person may be temporarily certified by MSHA to take...

  9. The RNA Binding Protein CsrA Is a Pleiotropic Regulator of the Locus of Enterocyte Effacement Pathogenicity Island of Enteropathogenic Escherichia coli▿

    PubMed Central

    Bhatt, Shantanu; Edwards, Adrianne Nehrling; Nguyen, Hang Thi Thu; Merlin, Didier; Romeo, Tony; Kalman, Daniel

    2009-01-01

    The attaching and effacing (A/E) pathogen enteropathogenic Escherichia coli (EPEC) forms characteristic actin-filled membranous protrusions upon infection of host cells termed pedestals. Here we examine the role of the RNA binding protein CsrA in the expression of virulence genes and proteins that are necessary for pedestal formation. The csrA mutant was defective in forming actin pedestals on epithelial cells and in disrupting transepithelial resistance across polarized epithelial cells. Consistent with reduced pedestal formation, secretion of the translocators EspA, EspB, and EspD and the effector Tir was substantially reduced in the csrA mutant. Purified CsrA specifically bound to the sepL espADB mRNA leader, and the corresponding transcript levels were reduced in the csrA mutant. In contrast, Tir synthesis was unaffected in the csrA mutant. Reduced secretion of Tir appeared to be in part due to decreased synthesis of EscD, an inner membrane architectural protein of the type III secretion system (TTSS) and EscF, a protein that forms the protruding needle complex of the TTSS. These effects were not mediated through the locus of enterocyte effacement (LEE) transcriptional regulator GrlA or Ler. In contrast to the csrA mutant, multicopy expression of csrA repressed transcription from LEE1, grlRA, LEE2, LEE5, escD, and LEE4, an effect mediated by GrlA and Ler. Consistent with its role in other organisms, CsrA also regulated flagellar motility and glycogen levels. Our findings suggest that CsrA governs virulence factor expression in an A/E pathogen by regulating mRNAs encoding translocators, effectors, or transcription factors. PMID:19581394

  10. A cellular stress response (CSR) that interacts with NADPH-P450 reductase (NPR) is a new regulator of hypoxic response.

    PubMed

    Oguro, Ami; Koyama, Chika; Xu, Jing; Imaoka, Susumu

    2014-02-28

    NADPH-P450 reductase (NPR) was previously found to contribute to the hypoxic response of cells, but the mechanism was not clarified. In this study, we identified a cellular stress response (CSR) as a new factor interacting with NPR by a yeast two-hybrid system. Overexpression of CSR enhanced the induction of erythropoietin and hypoxia response element (HRE) activity under hypoxia in human hepatocarcinoma cell lines (Hep3B), while knockdown of CSR suppressed them. This new finding regarding the interaction of NPR with CSR provides insight into the function of NPR in hypoxic response. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. I Will Do It If I Enjoy It! The Moderating Effect of Seeking Sensory Pleasure When Exposed to Participatory CSR Campaigns.

    PubMed

    Ruiz de Maya, Salvador; Lardín-Zambudio, Rafaela; López-López, Inés

    2015-01-01

    In an attempt to gain differentiation, companies are allocating resources to corporate social responsibility (CSR) initiatives. At the same time, they are giving consumers a more active role in the process of creating value. In this sense, consumer participation represents a new approach to gain competitive advantage. However, the effectiveness of consumer participation in CSR campaigns still remains unknown. With the purpose of shedding light on this issue, this paper shows that participatory CSR campaigns lead to greater consumer perceptions of CSR, which in turn results in more favorable attitudes toward the company. Furthermore, the effect is stronger for sensory pleasure seekers, whose involvement with the experience is greater. The findings contribute to the CSR literature and reveal important implications for marketers.

  12. I Will Do It If I Enjoy It! The Moderating Effect of Seeking Sensory Pleasure When Exposed to Participatory CSR Campaigns

    PubMed Central

    Ruiz de Maya, Salvador; Lardín-Zambudio, Rafaela; López-López, Inés

    2016-01-01

    In an attempt to gain differentiation, companies are allocating resources to corporate social responsibility (CSR) initiatives. At the same time, they are giving consumers a more active role in the process of creating value. In this sense, consumer participation represents a new approach to gain competitive advantage. However, the effectiveness of consumer participation in CSR campaigns still remains unknown. With the purpose of shedding light on this issue, this paper shows that participatory CSR campaigns lead to greater consumer perceptions of CSR, which in turn results in more favorable attitudes toward the company. Furthermore, the effect is stronger for sensory pleasure seekers, whose involvement with the experience is greater. The findings contribute to the CSR literature and reveal important implications for marketers. PMID:26779070

  13. The CSR-1 endogenous RNAi pathway ensures accurate transcriptional reprogramming during the oocyte-to-embryo transition in Caenorhabditis elegans.

    PubMed

    Fassnacht, Christina; Tocchini, Cristina; Kumari, Pooja; Gaidatzis, Dimos; Stadler, Michael B; Ciosk, Rafal

    2018-03-01

    Endogenous RNAi (endoRNAi) is a conserved mechanism for fine-tuning gene expression. In the nematode Caenorhabditis elegans, several endoRNAi pathways are required for the successful development of reproductive cells. The CSR-1 endoRNAi pathway promotes germ cell development, primarily by facilitating the expression of germline genes. In this study, we report a novel function for the CSR-1 pathway in preventing premature activation of embryonic transcription in the developing oocytes, which is accompanied by a general Pol II activation. This CSR-1 function requires its RNase activity, suggesting that, by controlling the levels of maternal mRNAs, CSR-1-dependent endoRNAi contributes to an orderly reprogramming of transcription during the oocyte-to-embryo transition.

  14. CsrA Participates in a PNPase Autoregulatory Mechanism by Selectively Repressing Translation of pnp Transcripts That Have Been Previously Processed by RNase III and PNPase

    PubMed Central

    Park, Hongmarn; Yakhnin, Helen; Connolly, Michael; Romeo, Tony

    2015-01-01

    ABSTRACT Csr is a conserved global regulatory system that represses or activates gene expression posttranscriptionally. CsrA of Escherichia coli is a homodimeric RNA binding protein that regulates transcription elongation, translation initiation, and mRNA stability by binding to the 5′ untranslated leader or initial coding sequence of target transcripts. pnp mRNA, encoding the 3′ to 5′ exoribonuclease polynucleotide phosphorylase (PNPase), was previously identified as a CsrA target by transcriptome sequencing (RNA-seq). Previous studies also showed that RNase III and PNPase participate in a pnp autoregulatory mechanism in which RNase III cleavage of the untranslated leader, followed by PNPase degradation of the resulting 5′ fragment, leads to pnp repression by an undefined translational repression mechanism. Here we demonstrate that CsrA binds to two sites in pnp leader RNA but only after the transcript is fully processed by RNase III and PNPase. In the absence of processing, both of the binding sites are sequestered in an RNA secondary structure, which prevents CsrA binding. The CsrA dimer bridges the upstream high-affinity site to the downstream site that overlaps the pnp Shine-Dalgarno sequence such that bound CsrA causes strong repression of pnp translation. CsrA-mediated translational repression also leads to a small increase in the pnp mRNA decay rate. Although CsrA has been shown to regulate translation and mRNA stability of numerous genes in a variety of organisms, this is the first example in which prior mRNA processing is required for CsrA-mediated regulation. IMPORTANCE CsrA protein represses translation of numerous mRNA targets, typically by binding to multiple sites in the untranslated leader region preceding the coding sequence. We found that CsrA represses translation of pnp by binding to two sites in the pnp leader transcript but only after it is processed by RNase III and PNPase. Processing by these two ribonucleases alters the m

  15. 26 CFR 1.1366-1 - Shareholder's share of items of an S corporation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... election to expense certain depreciable business expenses (section 179); medical, dental, etc., expenses... (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Small Business Corporations and Their Shareholders § 1.1366-1... used in the trade or business and involuntary conversions), grouped by applicable holding periods, by...

  16. 40 CFR 141.28 - Certified laboratories.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 141.28 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Monitoring and Analytical Requirements § 141.28 Certified... certified by the State except that measurements of alkalinity, calcium, conductivity, disinfectant residual...

  17. 40 CFR 141.28 - Certified laboratories.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 141.28 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) NATIONAL PRIMARY DRINKING WATER REGULATIONS Monitoring and Analytical Requirements § 141.28 Certified... certified by the State except that measurements of alkalinity, calcium, conductivity, disinfectant residual...

  18. 75 FR 66589 - Shareholder Approval of Executive Compensation and Golden Parachute Compensation

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-28

    ... 14A(b)(2). \\26\\ Exchange Act Section 14A(c). For a more detailed discussion of the advisory nature of... the shareholder votes required by Rule 14a-21, including disclosure of the non-binding nature of the...-binding nature of the vote. We are proposing to require additional disclosure so that information about...

  19. The CSR-1 endogenous RNAi pathway ensures accurate transcriptional reprogramming during the oocyte-to-embryo transition in Caenorhabditis elegans

    PubMed Central

    Tocchini, Cristina; Kumari, Pooja; Gaidatzis, Dimos

    2018-01-01

    Endogenous RNAi (endoRNAi) is a conserved mechanism for fine-tuning gene expression. In the nematode Caenorhabditis elegans, several endoRNAi pathways are required for the successful development of reproductive cells. The CSR-1 endoRNAi pathway promotes germ cell development, primarily by facilitating the expression of germline genes. In this study, we report a novel function for the CSR-1 pathway in preventing premature activation of embryonic transcription in the developing oocytes, which is accompanied by a general Pol II activation. This CSR-1 function requires its RNase activity, suggesting that, by controlling the levels of maternal mRNAs, CSR-1-dependent endoRNAi contributes to an orderly reprogramming of transcription during the oocyte-to-embryo transition. PMID:29579041

  20. A T0/Trigger detector for the External Target Experiment at CSR

    NASA Astrophysics Data System (ADS)

    Hu, D.; Shao, M.; Sun, Y.; Li, C.; Chen, H.; Tang, Z.; Zhang, Y.; Zhou, J.; Zeng, H.; Zhao, X.; You, W.; Song, G.; Deng, P.; Lu, J.; Zhao, L.

    2017-06-01

    A new T0/Trigger detector based on multi-gap resistive plate chamber (MRPC) technology has been constructed and tested for the external target experiment (ETE) at HIRFL-CSR. It measures the multiplicity and timing information of particles produced in heavy-ion collisions at the target region, providing necessary event collision time (T0) and collision centrality with high precision. Monte-Carlo simulation shows a time resolution of several tens of picosecond can be achieved at central collisions. The experimental tests have been performed for this prototype detector at the CSR-ETE. The preliminary results are shown to demonstrate the performance of the T0/Trigger detector.

  1. Certified Electronics Recyclers

    EPA Pesticide Factsheets

    Learn how EPA encourages all electronics recyclers become certified by demonstrating to an accredited, independent third-party auditor and that they meet specific standards to safely recycle and manage electronics.

  2. Tied Mixtures in the Lincoln Robust CSR

    DTIC Science & Technology

    1989-01-01

    reporting burden for the collection of information is estimated to average 1 hour per response , including the time for reviewing instructions, searching...TITLE AND SUBTITLE Tied Mixtures in the Lincoln Robust CSR 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d...ABSTRACT 18. NUMBER OF PAGES 10 19a. NAME OF RESPONSIBLE PERSON a. REPORT unclassified b. ABSTRACT unclassified c. THIS PAGE unclassified

  3. 22 CFR 92.62 - Captioning and certifying depositions.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 22 Foreign Relations 1 2011-04-01 2011-04-01 false Captioning and certifying depositions. 92.62... SERVICES Depositions and Letters Rogatory § 92.62 Captioning and certifying depositions. The notarizing officer should prepare a caption for every deposition; should certify on the deposition that the witness...

  4. 22 CFR 92.62 - Captioning and certifying depositions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Captioning and certifying depositions. 92.62... SERVICES Depositions and Letters Rogatory § 92.62 Captioning and certifying depositions. The notarizing officer should prepare a caption for every deposition; should certify on the deposition that the witness...

  5. Effects of CSR Generated from Upstream Bends in a Laser Plasma Storage Ring

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mitchell, C.; Qiang, J.; Venturini, M.

    The recent proposal [1] of a Laser Plasma Storage Ring (LPSR) envisions the use of a laser-plasma (LP) acceleration module to inject an electron beam into a compact 500 MeV storage ring. Electron bunches generated by LP methods are naturally very short (tens of femtoseconds), presenting peak currents on the order of 10 kA or higher. Of obvious concern is the impact of collective effects and in particular Coherent Synchrotron Radiation (CSR) on the beam dynamics in the storage ring. Available simulation codes (e.g. Elegant [2]) usually include transient CSR effects but neglect the contribution of radiation emitted from trailingmore » magnets. In a compact storage ring, with dipole magnets close to each other, cross talking between different magnets could in principle be important.In this note we investigate this effect for the proposed LPSR and show that, in fact, this effect is relatively small. However our analysis also indicates that CSR effects in general would be quite strong and deserve a a careful study.« less

  6. Certified Nurses' Aide Job-Related Curriculum.

    ERIC Educational Resources Information Center

    Massachusetts Career Development Inst., Springfield.

    This document, which is designed for students preparing to become a certified nurses' aide, contains instructional text and learning activities organized in nine sections. The following topics are covered: the role of the certified nurse's aide (job duties, personal health, professionalism, code of ethics); infection control (the infection…

  7. 26 CFR 1.1298-3 - Deemed sale or deemed dividend election by a U.S. person that is a shareholder of a former PFIC.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... its stock in the former PFIC for its fair market value on the termination date, as defined in... sale election, the shareholder's stock with respect to which the election was made under this paragraph... the deemed dividend election, the shareholder's stock with respect to which the election was made...

  8. The post-transcriptional regulatory system CSR controls the balance of metabolic pools in upper glycolysis of Escherichia coli.

    PubMed

    Morin, Manon; Ropers, Delphine; Letisse, Fabien; Laguerre, Sandrine; Portais, Jean-Charles; Cocaign-Bousquet, Muriel; Enjalbert, Brice

    2016-05-01

    Metabolic control in Escherichia coli is a complex process involving multilevel regulatory systems but the involvement of post-transcriptional regulation is uncertain. The post-transcriptional factor CsrA is stated as being the only regulator essential for the use of glycolytic substrates. A dozen enzymes in the central carbon metabolism (CCM) have been reported as potentially controlled by CsrA, but its impact on the CCM functioning has not been demonstrated. Here, a multiscale analysis was performed in a wild-type strain and its isogenic mutant attenuated for CsrA (including growth parameters, gene expression levels, metabolite pools, abundance of enzymes and fluxes). Data integration and regulation analysis showed a coordinated control of the expression of glycolytic enzymes. This also revealed the imbalance of metabolite pools in the csrA mutant upper glycolysis, before the phosphofructokinase PfkA step. This imbalance is associated with a glucose-phosphate stress. Restoring PfkA activity in the csrA mutant strain suppressed this stress and increased the mutant growth rate on glucose. Thus, the carbon storage regulator system is essential for the effective functioning of the upper glycolysis mainly through its control of PfkA. This work demonstrates the pivotal role of post-transcriptional regulation to shape the carbon metabolism. © 2016 John Wiley & Sons Ltd.

  9. 7 CFR 97.122 - Certified seed only election.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Certified seed only election. 97.122 Section 97.122... PLANT VARIETY AND PROTECTION Reissuance of Certificate § 97.122 Certified seed only election. When an... of certified seed, a new certificate may be issued upon return of the original certificate to the...

  10. 7 CFR 97.122 - Certified seed only election.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Certified seed only election. 97.122 Section 97.122... PLANT VARIETY AND PROTECTION Reissuance of Certificate § 97.122 Certified seed only election. When an... of certified seed, a new certificate may be issued upon return of the original certificate to the...

  11. List of EPA Certified Forced-Air Furnaces

    EPA Pesticide Factsheets

    The EPA-Certified Forced-Air Furnace list contains EPA-certified forced-air furnaces that meet the 2015 NSPS for New Residential Wood Heaters, New Residential Hydronic Heaters and Forced-Air Furnaces.

  12. ENERGY STAR Certified Data Center Storage

    EPA Pesticide Factsheets

    Certified models meet all ENERGY STAR requirements as listed in the Version 1.0 ENERGY STAR Program Requirements for Data Center Storage that are effective as of December 2, 2013. A detailed listing of key efficiency criteria are available at http://www.energystar.gov/certified-products/detail/data_center_storage

  13. 26 CFR 1.852-4 - Method of taxation of shareholders of regulated investment companies.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... investment companies. 1.852-4 Section 1.852-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.852-4 Method of taxation of shareholders of regulated investment...

  14. 26 CFR 1.852-4 - Method of taxation of shareholders of regulated investment companies.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... investment companies. 1.852-4 Section 1.852-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.852-4 Method of taxation of shareholders of regulated investment...

  15. 26 CFR 1.852-4 - Method of taxation of shareholders of regulated investment companies.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... investment companies. 1.852-4 Section 1.852-4 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Regulated Investment Companies and Real Estate Investment Trusts § 1.852-4 Method of taxation of shareholders of regulated investment...

  16. Thymineless death is inhibited by CsrA in Escherichia coli lacking the SOS response.

    PubMed

    Hamilton, Holly M; Wilson, Ray; Blythe, Martin; Nehring, Ralf B; Fonville, Natalie C; Louis, Edward J; Rosenberg, Susan M

    2013-11-01

    Thymineless death (TLD) is the rapid loss of colony-forming ability in bacterial, yeast and human cells starved for thymine, and is the mechanism of action of common chemotherapeutic drugs. In Escherichia coli, significant loss of viability during TLD requires the SOS replication-stress/DNA-damage response, specifically its role in inducing the inhibitor of cell division, SulA. An independent RecQ- and RecJ-dependent TLD pathway accounts for a similarly large additional component of TLD, and a third SOS- and RecQ/J-independent TLD pathway has also been observed. Although two groups have implicated the SOS-response in TLD, an SOS-deficient mutant strain from an earlier study was found to be sensitive to thymine deprivation. We performed whole-genome resequencing on that SOS-deficient strain and find that, compared with the SOS-proficient control strain, it contains five mutations in addition to the SOS-blocking lexA(Ind(-)) mutation. One of the additional mutations, csrA, confers TLD sensitivity specifically in SOS-defective strains. We find that CsrA, a carbon storage regulator, reduces TLD in SOS- or SulA-defective cells, and that the increased TLD that occurs in csrA(-) SOS-defective cells is dependent on RecQ. We consider a hypothesis in which the modulation of nucleotide pools by CsrA might inhibit TLD specifically in SOS-deficient (SulA-deficient) cells. Copyright © 2013 Elsevier B.V. All rights reserved.

  17. The certifying surgeons

    PubMed Central

    Bloor, D. U.

    1981-01-01

    The origin and work of the nineteenth century certifying surgeons is described. Their place within the broad spectrum of general practice is emphasized and their efforts to improve the welfare of children is noted. PMID:7021817

  18. A multitasking Argonaute: exploring the many facets of C. elegans CSR-1.

    PubMed

    Wedeles, Christopher J; Wu, Monica Z; Claycomb, Julie M

    2013-12-01

    While initial studies of small RNA-mediated gene regulatory pathways focused on the cytoplasmic functions of such pathways, identifying roles for Argonaute/small RNA pathways in modulating chromatin and organizing the genome has become a topic of intense research in recent years. Nuclear regulatory mechanisms for Argonaute/small RNA pathways appear to be widespread, in organisms ranging from plants to fission yeast, Caenorhabditis elegans to humans. As the effectors of small RNA-mediated gene regulatory pathways, Argonaute proteins guide the chromatin-directed activities of these pathways. Of particular interest is the C. elegans Argonaute, chromosome segregation and RNAi deficient (CSR-1), which has been implicated in such diverse functions as organizing the holocentromeres of worm chromosomes, modulating germline chromatin, protecting the genome from foreign nucleic acid, regulating histone levels, executing RNAi, and inhibiting translation in conjunction with Pumilio proteins. CSR-1 interacts with small RNAs known as 22G-RNAs, which have complementarity to 25 % of the protein coding genes. This peculiar Argonaute is the only essential C. elegans Argonaute out of 24 family members in total. Here, we summarize the current understanding of CSR-1 functions in the worm, with emphasis on the chromatin-directed activities of this ever-intriguing Argonaute.

  19. 21 CFR 82.6 - Certifiable mixtures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... PROVISIONALLY LISTED COLORS AND SPECIFICATIONS General Provisions § 82.6 Certifiable mixtures. (a) A batch of a mixture which contains no straight color listed in subpart C or D may be certified for use in food, drugs... provisions of this part, for use only in drugs and cosmetics, if: (1) Each coal-tar color used as an...

  20. 76 FR 19310 - Information Collection; Certified State Mediation Program

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-07

    ... DEPARTMENT OF AGRICULTURE Farm Service Agency Information Collection; Certified State Mediation... supports the Certified State Mediation Program. The information collection is necessary to ensure the grant... submit comments by any of the following methods: Mail: Carol Wagner, Certified State Mediation Program...

  1. 26 CFR 1.1297-3 - Deemed sale or deemed dividend election by a U.S. person that is a shareholder of a section 1297...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... election with respect to a section 1297(e) PFIC shall be treated as having sold all of its stock in the... recognized. After the deemed sale election, the shareholder's stock with respect to which the election was... basis. A shareholder that makes the deemed sale election increases its adjusted basis of the PFIC stock...

  2. 7 CFR 205.662 - Noncompliance procedure for certified operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Administrative Compliance § 205.662... of a certified operation by a certifying agent or a State organic program's governing State official... demonstrates that each noncompliance has been resolved, the certifying agent or the State organic program's...

  3. Acute abdomen due to group A streptococcus bacteremia caused by an isolate with a mutation in the csrS gene.

    PubMed

    Kaneko, Masahiko; Maruta, Masaki; Shikata, Hisaharu; Hanayama, Masakazu; Ikebe, Tadayoshi

    2015-11-01

    Streptococcus pyogenes (group A streptococcus) is an aerobic gram-positive coccus that causes infections ranging from non-invasive pharyngitis to severely invasive necrotizing fasciitis. Mutations in csrS/csrR and rgg, negative regulator genes of group A streptococcus, are crucial factors in the pathogenesis of streptococcal toxic shock syndrome, which is a severe, invasive infection characterized by sudden onset of shock and multiorgan failure, resulting in a high mortality rate. Here we present a case of group A streptococcal bacteremia in a 28-year-old Japanese woman with no relevant previous medical history. The patient developed progressive abdominal symptoms that may have been due to spontaneous bacterial peritonitis, followed by a state of shock, which did not fulfill the proposed criteria for streptococcal toxic shock. The isolate was found to harbor a mutation in the negative regulator csrS gene, whereas the csrR and rgg genes were intact. It was noteworthy that this strain carrying a csrS mutation had caused group A streptococcal bacteremia characterized by acute abdomen as the presenting symptom in a young individual who had been previously healthy. This case indicates that group A streptococcus with csrS mutations has potential virulence factors that are associated with the onset of group A streptococcal bacteremia that does not meet the diagnostic criteria for streptococcal toxic shock syndrome. Copyright © 2015 Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

  4. 7 CFR 201.67 - Seed certifying agency standards and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Seed certifying agency standards and procedures. 201...) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.67 Seed certifying agency standards and procedures. In order to qualify as a seed certifying agency for purposes of section 101(a)(25) of the Federal...

  5. 7 CFR 201.67 - Seed certifying agency standards and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Seed certifying agency standards and procedures. 201...) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.67 Seed certifying agency standards and procedures. In order to qualify as a seed certifying agency for purposes of section 101(a)(25) of the Federal...

  6. 31 CFR 315.57 - When a certifying officer may not certify.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (Continued) FISCAL SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS GOVERNING U.S. SAVINGS BONDS, SERIES A, B, C, D, E, F, G, H, J, AND K, AND U.S. SAVINGS NOTES Certifying Officers § 315...

  7. CSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline

    PubMed Central

    Campbell, Anne C.; Updike, Dustin L.

    2015-01-01

    Germ granules (P granules) in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency. Sterility in the absence of P granules is often accompanied by the misexpression of soma-specific proteins and the initiation of somatic differentiation in germ cells. To investigate whether this is caused by the accumulation of somatic transcripts, we performed mRNA-seq on dissected germlines with and without P granules. Strikingly, we found that somatic transcripts do not increase in the young adult germline when P granules are impaired. Instead, we found that impairing P granules causes sperm-specific mRNAs to become highly overexpressed. This includes the accumulation of major sperm protein (MSP) transcripts in germ cells, a phenotype that is suppressed by feminization of the germline. A core component of P granules, the endo-siRNA-binding Argonaute protein CSR-1, has recently been ascribed with the ability to license transcripts for germline expression. However, impairing CSR-1 has very little effect on the accumulation of its mRNA targets. Instead, we found that CSR-1 functions with P granules to prevent MSP and sperm-specific mRNAs from being transcribed in the hermaphrodite germline. These findings suggest that P granules protect germline integrity through two different mechanisms, by (1) preventing the inappropriate expression of somatic proteins at the level of translational regulation, and by (2) functioning with CSR-1 to limit the domain of sperm-specific expression at the level of transcription. PMID:25968310

  8. CSR-1 and P granules suppress sperm-specific transcription in the C. elegans germline.

    PubMed

    Campbell, Anne C; Updike, Dustin L

    2015-05-15

    Germ granules (P granules) in C. elegans are required for fertility and function to maintain germ cell identity and pluripotency. Sterility in the absence of P granules is often accompanied by the misexpression of soma-specific proteins and the initiation of somatic differentiation in germ cells. To investigate whether this is caused by the accumulation of somatic transcripts, we performed mRNA-seq on dissected germlines with and without P granules. Strikingly, we found that somatic transcripts do not increase in the young adult germline when P granules are impaired. Instead, we found that impairing P granules causes sperm-specific mRNAs to become highly overexpressed. This includes the accumulation of major sperm protein (MSP) transcripts in germ cells, a phenotype that is suppressed by feminization of the germline. A core component of P granules, the endo-siRNA-binding Argonaute protein CSR-1, has recently been ascribed with the ability to license transcripts for germline expression. However, impairing CSR-1 has very little effect on the accumulation of its mRNA targets. Instead, we found that CSR-1 functions with P granules to prevent MSP and sperm-specific mRNAs from being transcribed in the hermaphrodite germline. These findings suggest that P granules protect germline integrity through two different mechanisms, by (1) preventing the inappropriate expression of somatic proteins at the level of translational regulation, and by (2) functioning with CSR-1 to limit the domain of sperm-specific expression at the level of transcription. © 2015. Published by The Company of Biologists Ltd.

  9. 30 CFR 90.203 - Certified person; maintenance and calibration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... COAL MINE SAFETY AND HEALTH MANDATORY HEALTH STANDARDS-COAL MINERS WHO HAVE EVIDENCE OF THE DEVELOPMENT OF PNEUMOCONIOSIS Sampling Procedures § 90.203 Certified person; maintenance and calibration. (a) Approved sampling devices shall be maintained and calibrated by a certified person. (b) To be certified, a...

  10. Meeting the Needs of Alternatively Certified Teachers.

    ERIC Educational Resources Information Center

    Chesley, Lynne Scott; Wood, Fred H.; Zepeda, Sally J.

    1997-01-01

    The unique needs of alternatively certified teachers merit a customized induction program. This paper presents data from a recent study of beginning alternatively certified teachers in Oklahoma, examining characteristics of the teachers studied, frustrations among new teachers, insufficient resources and materials, training needs, relationships…

  11. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TREASURY (CONTINUED) LIQUIDATION OF DUTIES Conversion of Foreign Currency § 159.34 Certified quarterly rate. (a) Countries for which quarterly rate is certified. For the currency of each of the following... York for such foreign currency for a day in that quarter: Australia, Austria, Belgium, Brazil, Canada...

  12. 25 CFR 81.23 - Posting and certifying election results.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Posting and certifying election results. 81.23 Section 81... REORGANIZATION UNDER A FEDERAL STATUTE § 81.23 Posting and certifying election results. (a) The results of the... appropriate public places determined by the election board. (b) The election board shall certify the results...

  13. 25 CFR 81.23 - Posting and certifying election results.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Posting and certifying election results. 81.23 Section 81... REORGANIZATION UNDER A FEDERAL STATUTE § 81.23 Posting and certifying election results. (a) The results of the... appropriate public places determined by the election board. (b) The election board shall certify the results...

  14. 25 CFR 81.23 - Posting and certifying election results.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Posting and certifying election results. 81.23 Section 81... REORGANIZATION UNDER A FEDERAL STATUTE § 81.23 Posting and certifying election results. (a) The results of the... appropriate public places determined by the election board. (b) The election board shall certify the results...

  15. 25 CFR 81.23 - Posting and certifying election results.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Posting and certifying election results. 81.23 Section 81... REORGANIZATION UNDER A FEDERAL STATUTE § 81.23 Posting and certifying election results. (a) The results of the... appropriate public places determined by the election board. (b) The election board shall certify the results...

  16. 25 CFR 81.23 - Posting and certifying election results.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Posting and certifying election results. 81.23 Section 81... REORGANIZATION UNDER A FEDERAL STATUTE § 81.23 Posting and certifying election results. (a) The results of the... appropriate public places determined by the election board. (b) The election board shall certify the results...

  17. Nuclear stopping and collective flow in CSR/LanZhou energy region

    NASA Astrophysics Data System (ADS)

    Luo, X.-F.; Dong, X.; Shao, M.; Li, C.; Chen, H.-F.; Wu, K.-J.; Xu, H.-S.

    2011-06-01

    Nuclear stopping and collective flow for two pairs of symmetric colliding nuclei: 238U+238U and 129Xe+129Xe, which are proposed to be accelerated on Cooling Storage Ring (CSR), External Target Facility (ETF), LanZhou, China, are studied by a hadronic transport model ART1.0. The incident beam energy of Uranium and Xenon can be delivered up to 520 MeV/nucleon and 900MeV/nucleon, respectively. At this CSR energy region, the hot, dense nuclear matter are thought to be obtained in the lab, which is an idea circumstance to study the nuclear equation of state (EoS). As deformation of the Uranium nuclei, it is predicted that significant large baryon density in the tip-tip U+U collision patterns and the large elliptic flow in body-body collision pattern are both avail to study the nuclear EoS.

  18. A call to action on women's health: putting corporate CSR standards for workplace health on the global health agenda.

    PubMed

    Wofford, David; MacDonald, Shawn; Rodehau, Carolyn

    2016-11-04

    Business operates within a Corporate Social Responsibility (CSR) system that the global health community should harness to advance women's health and related sustainable development goals for workers and communities in low- and middle-income countries. Corporations and their vast networks of supplier companies, particularly in manufacturing and agribusiness, employ millions of workers, increasingly comprised of young women, who lack access to health information, products and services. However, occupational safety and health practices focus primarily on safety issues and fail to address the health needs, including reproductive health, of women workers. CSR policy has focused on shaping corporate policies and practices related to the environment, labor, and human rights, but has also ignored the health needs of women workers. The authors present a new way for global health to understand CSR - as a set of regulatory processes governed by civil society, international institutions, business, and government that set, monitor, and enforce emerging standards related to the role of business in society. They call this the CSR system. They argue that the global health community needs to think differently about the role of corporations in public health, which has been as "partners," and that the global health practitioners should play the same advocacy role in the CSR system for corporate health policies as it does for government and international health policies.

  19. Self-Certified Sickness Absence among Young Municipal Employees-Changes from 2002 to 2016 and Occupational Class Differences.

    PubMed

    Sumanen, Hilla; Pietiläinen, Olli; Mänty, Minna

    2017-09-26

    We examined changes in self-certified, one-to-three day sickness absence (SA) among young employees from 2002 to 2016 and the magnitude of occupational class differences during that period. All 18-34-year-old employees of the City of Helsinki, Finland were included (2002-2016, n = ~11,725 per year). Employer's personnel and SA registers were used. Occupational class was categorized to four groups. Changes in self-certified SA from 2002 to 2016 were analyzed with Joinpoint regression and the magnitudes of occupational class differences were estimated with the relative index of inequality (RII). Most of the trends first increased and turned to decrease in 2007/2010. Managers and professionals had the least amount of SA, but steadily increasing trends were observed among men. Self-certified SA followed only partially the typical socioeconomic gradient, as routine non-manuals had the highest levels of SA. The magnitude of occupational class differences in self-certified SA was stable during the study period only among women. Self-certified SA and occupational class differences have increased in recent years among men in the lower occupational classes. Socioeconomic differences exist in self-certified SA among young employees, but gradient is only partial. Overall, high amounts of self-certified SA especially in the lower occupational classes require further studies and preventive measures.

  20. Quantitative Financial Analysis of Alternative Energy Efficiency Shareholder Incentive Mechanisms

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cappers, Peter; Goldman, Charles; Chait, Michele

    2008-08-03

    Rising energy prices and climate change are central issues in the debate about our nation's energy policy. Many are demanding increased energy efficiency as a way to help reduce greenhouse gas emissions and lower the total cost of electricity and energy services for consumers and businesses. Yet, as the National Action Plan on Energy Efficiency (NAPEE) pointed out, many utilities continue to shy away from seriously expanding their energy efficiency program offerings because they claim there is insufficient profit-motivation, or even a financial disincentive, when compared to supply-side investments. With the recent introduction of Duke Energy's Save-a-Watt incentive mechanism andmore » ongoing discussions about decoupling, regulators and policymakers are now faced with an expanded and diverse landscape of financial incentive mechanisms, Determining the 'right' way forward to promote deep and sustainable demand side resource programs is challenging. Due to the renaissance that energy efficiency is currently experiencing, many want to better understand the tradeoffs in stakeholder benefits between these alternative incentive structures before aggressively embarking on a path for which course corrections can be time-consuming and costly. Using a prototypical Southwest utility and a publicly available financial model, we show how various stakeholders (e.g. shareholders, ratepayers, etc.) are affected by these different types of shareholder incentive mechanisms under varying assumptions about program portfolios. This quantitative analysis compares the financial consequences associated with a wide range of alternative incentive structures. The results will help regulators and policymakers better understand the financial implications of DSR program incentive regulation.« less

  1. 30-Day Mortality and Readmission after Hemorrhagic Stroke among Medicare Beneficiaries in Joint Commission Primary Stroke Center Certified and Non-Certified Hospitals

    PubMed Central

    Lichtman, Judith H.; Jones, Sara B.; Leifheit-Limson, Erica C.; Wang, Yun; Goldstein, Larry B.

    2012-01-01

    Background and Purpose Ischemic stroke patients treated at Joint Commission Primary Stroke Center (JC-PSC) certified hospitals have better outcomes. Data reflecting the impact of JC-PSC status on outcomes after hemorrhagic stroke are limited. We determined whether 30-day mortality and readmission rates after hemorrhagic stroke differed for patients treated at JC-PSC certified versus non-certified hospitals. Methods The study included all fee-for-service Medicare beneficiaries ≥65 years old with a primary discharge diagnosis of subarachnoid hemorrhage (SAH) or intracerebral hemorrhage (ICH) in 2006. Covariate-adjusted logistic and Cox proportional hazards regression assessed the effect of care at a JC-PSC certified hospital on 30-day mortality and readmission. Results There were 2,305 SAH and 8,708 ICH discharges from JC-PSC certified hospitals and 3,892 SAH and 22,564 ICH discharges from non-certified hospitals. Unadjusted in-hospital mortality (SAH: 27.5% vs. 33.2%, p<0.0001; ICH: 27.9% vs. 29.6%, p=0.003) and 30-day mortality (SAH: 35.1% vs. 44.0%, p<0.0001; ICH: 39.8% vs. 42.4%, p<0.0001) were lower in JC-PSC hospitals, but 30-day readmission rates were similar (SAH: 17.0% vs. 17.0%, p=0.97; ICH: 16.0% vs. 15.5%; p=0.29). Risk-adjusted 30-day mortality was 34% lower (OR 0.66, 95% CI 0.58–0.76) after SAH and 14% lower (OR 0.86, 95% CI 0.80–0.92) after ICH for patients discharged from JC-PSC certified hospitals. There was no difference in 30-day risk-adjusted readmission rates for SAH or ICH based on JC-PSC status. Conclusions Patients treated at JC-PSC certified hospitals had lower risk-adjusted mortality rates for both SAH and ICH but similar 30-day readmission rates as compared with non-certified hospitals. PMID:22033986

  2. 20 CFR 403.155 - Does SSA certify records?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the disclosure and will not certify copies of records that have left our custody. A request for certified copies of records previously released is considered a new request for records. Fees for this...

  3. 20 CFR 403.155 - Does SSA certify records?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... the disclosure and will not certify copies of records that have left our custody. A request for certified copies of records previously released is considered a new request for records. Fees for this...

  4. The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression.

    PubMed

    Seth, Meetu; Shirayama, Masaki; Gu, Weifeng; Ishidate, Takao; Conte, Darryl; Mello, Craig C

    2013-12-23

    Organisms can develop adaptive sequence-specific immunity by reexpressing pathogen-specific small RNAs that guide gene silencing. For example, the C. elegans PIWI-Argonaute/piwi-interacting RNA (piRNA) pathway recruits RNA-dependent RNA polymerase (RdRP) to foreign sequences to amplify a transgenerational small-RNA-induced epigenetic silencing signal (termed RNAe). Here, we provide evidence that, in addition to an adaptive memory of silenced sequences, C. elegans can also develop an opposing adaptive memory of expressed/self-mRNAs. We refer to this mechanism, which can prevent or reverse RNAe, as RNA-induced epigenetic gene activation (RNAa). We show that CSR-1, which engages RdRP-amplified small RNAs complementary to germline-expressed mRNAs, is required for RNAa. We show that a transgene with RNAa activity also exhibits accumulation of cognate CSR-1 small RNAs. Our findings suggest that C. elegans adaptively acquires and maintains a transgenerational CSR-1 memory that recognizes and protects self-mRNAs, allowing piRNAs to recognize foreign sequences innately, without the need for prior exposure

  5. The C. elegans CSR-1 Argonaute pathway counteracts epigenetic silencing to promote germline gene expression

    PubMed Central

    Seth, Meetu; Shirayama, Masaki; Gu, Weifeng; Ishidate, Takao; Conte, Darryl; Mello, Craig C.

    2014-01-01

    SUMMARY Organisms can develop adaptive sequence-specific immunity by re-expressing pathogen-specific small RNAs that guide gene silencing. For example, the C. elegans PIWI-Argonaute/piRNA pathway recruits RNA-dependent RNA polymerase RdRP to foreign sequences to amplify a trans-generational small RNA-induced epigenetic silencing signal (termed RNAe). Here we provide evidence that in addition to an adaptive memory of silenced sequences, C. elegans can also develop an opposing adaptive memory of expressed/self mRNAs. We refer to this mechanism, which can prevent or reverse RNAe as RNA-induced epigenetic gene activation (RNAa). We show that CSR-1, which engages RdRP-amplified small RNAs complementary to germline-expressed mRNAs, is required for RNAa. We show that a transgene with RNAa activity also exhibits accumulation of cognate CSR-1 small RNAs. Our findings suggest that C. elegans adaptively acquires and maintains a trans-generational CSR-1 memory that recognizes and protects self mRNAs, allowing piRNAs to recognize foreign sequences innately, without need for prior exposure. PMID:24360782

  6. 19 CFR 159.36 - Multiple certified rates.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... multiple rates have been certified for a foreign currency, the rate to be used for Customs purposes shall... TREASURY (CONTINUED) LIQUIDATION OF DUTIES Conversion of Foreign Currency § 159.36 Multiple certified rates... rates of exchange (e.g., official and free) for a foreign currency: (a) Rates to be published. When the...

  7. 7 CFR 97.143 - Certified seed only.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Certified seed only. 97.143 Section 97.143 Agriculture... PLANT VARIETY AND PROTECTION Marking Or Labeling Provisions § 97.143 Certified seed only. (a) Upon filing an application, or amendment thereto, specifying seed of the variety is to be sold by variety name...

  8. 7 CFR 97.143 - Certified seed only.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Certified seed only. 97.143 Section 97.143 Agriculture... PLANT VARIETY AND PROTECTION Marking Or Labeling Provisions § 97.143 Certified seed only. (a) Upon filing an application, or amendment thereto, specifying seed of the variety is to be sold by variety name...

  9. 26 CFR 1.857-6 - Method of taxation of shareholders of real estate investment trusts.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Real Estate Investment Trusts § 1.857-6 Method of taxation of shareholders of real estate investment trusts. (a) Ordinary income... receiving dividends from a real estate investment trust shall include such dividends in gross income for the...

  10. 26 CFR 1.857-6 - Method of taxation of shareholders of real estate investment trusts.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Real Estate Investment Trusts § 1.857-6 Method of taxation of shareholders of real estate investment trusts. (a) Ordinary income... receiving dividends from a real estate investment trust shall include such dividends in gross income for the...

  11. 26 CFR 1.857-6 - Method of taxation of shareholders of real estate investment trusts.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES (CONTINUED) Real Estate Investment Trusts § 1.857-6 Method of taxation of shareholders of real estate investment trusts. (a) Ordinary income... receiving dividends from a real estate investment trust shall include such dividends in gross income for the...

  12. 78 FR 79652 - Taxation of U.S. Persons That Are Shareholders of Section 1291 Funds

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-31

    ... DEPARTMENT OF THE TREASURY Internal Revenue Service 26 CFR Part 1 [REG-113350-13] RIN 1545-BL56 Taxation of U.S. Persons That Are Shareholders of Section 1291 Funds AGENCY: Internal Revenue Service (IRS), Treasury. ACTION: Partial withdrawal of notice of proposed rulemaking. SUMMARY: This document withdraws a...

  13. 26 CFR 1.951-1 - Amounts included in gross income of United States shareholders.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... corporation it had distributed pro rata to its shareholders an amount which bears the same ratio to its... bears the same ratio to the subpart F income of such corporation for the taxable year as the part of... received by B 15 (ii) B's pro rata share of the amount which bears the same ratio to M Corporation's...

  14. 26 CFR 1.951-1 - Amounts included in gross income of United States shareholders.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... corporation it had distributed pro rata to its shareholders an amount which bears the same ratio to its... bears the same ratio to the subpart F income of such corporation for the taxable year as the part of... received by B 15 (ii) B's pro rata share of the amount which bears the same ratio to M Corporation's...

  15. 19 CFR 159.35 - Certified daily rate.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... TREASURY (CONTINUED) LIQUIDATION OF DUTIES Conversion of Foreign Currency § 159.35 Certified daily rate. The daily buying rate of foreign currency which is determined by the Federal Reserve Bank of New York and certified to the Secretary of the Treasury in accordance with 31 U.S.C. 5151(e) shall be used for...

  16. Certified Athletic Trainers in Our Secondary Schools.

    ERIC Educational Resources Information Center

    Stopka, Christine; Shimon, Jane M.; Horodyski, MaryBeth; Deere, Randy; Bolger, Christine

    2002-01-01

    Describes the medical, legal, and educational benefits of having a certified athletic trainer in the secondary school, explaining that they can prevent or lessen the severity of an injury or chance of re-injury. The article presents eight options for hiring a certified athletic trainer and offers suggestions and resources for locating one. (SM)

  17. Comprehensive School Reform Models: A Study Guide for Comparing CSR Models (and How Well They Meet Minnesota's Learning Standards).

    ERIC Educational Resources Information Center

    St. John, Edward P.; Loescher, Siri; Jacob, Stacy; Cekic, Osman; Kupersmith, Leigh; Musoba, Glenda Droogsma

    A growing number of schools are exploring the prospect of applying for funding to implement a Comprehensive School Reform (CSR) model. But the process of selecting a CSR model can be complicated because it frequently involves self-study and a review of models to determine which models best meet the needs of the school. This study guide is intended…

  18. Human Resource Development: An Examination of Perceived Training Needs of Certified Rehabilitation Counselors.

    ERIC Educational Resources Information Center

    Szymanski, Edna Mora; And Others

    1993-01-01

    Investigated human resource development needs of certified rehabilitation counselors (n=1,535). Counselors reported development needs in vocational services; medical/psychosocial aspects; case management/services; and social, cultural, and environmental issues. Significant differences in development needs were found across job levels, job…

  19. 7 CFR 201.70 - Limitations of generations for certified seed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Limitations of generations for certified seed. 201.70... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.70 Limitations of generations for certified seed...

  20. 7 CFR 201.70 - Limitations of generations for certified seed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Limitations of generations for certified seed. 201.70... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.70 Limitations of generations for certified seed...

  1. 7 CFR 457.145 - Potato crop insurance-certified seed endorsement.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 6 2013-01-01 2013-01-01 false Potato crop insurance-certified seed endorsement. 457... INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE COMMON CROP INSURANCE REGULATIONS § 457.145 Potato crop insurance—certified seed endorsement. The Potato Crop Insurance Certified Seed Endorsement Provisions for...

  2. 7 CFR 457.145 - Potato crop insurance-certified seed endorsement.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 6 2012-01-01 2012-01-01 false Potato crop insurance-certified seed endorsement. 457... INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE COMMON CROP INSURANCE REGULATIONS § 457.145 Potato crop insurance—certified seed endorsement. The Potato Crop Insurance Certified Seed Endorsement Provisions for...

  3. 7 CFR 457.145 - Potato crop insurance-certified seed endorsement.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 6 2014-01-01 2014-01-01 false Potato crop insurance-certified seed endorsement. 457... INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE COMMON CROP INSURANCE REGULATIONS § 457.145 Potato crop insurance—certified seed endorsement. The Potato Crop Insurance Certified Seed Endorsement Provisions for...

  4. 7 CFR 457.145 - Potato crop insurance-certified seed endorsement.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 6 2011-01-01 2011-01-01 false Potato crop insurance-certified seed endorsement. 457... INSURANCE CORPORATION, DEPARTMENT OF AGRICULTURE COMMON CROP INSURANCE REGULATIONS § 457.145 Potato crop insurance—certified seed endorsement. The Potato Crop Insurance Certified Seed Endorsement Provisions for...

  5. 7 CFR 205.661 - Investigation of certified operations.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Administrative Compliance § 205.661 Investigation of... regulations of this part concerning production and handling operations certified as organic by the certifying...

  6. 13 CFR 120.812 - Probationary period for newly certified CDCs.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... certified CDCs. 120.812 Section 120.812 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development Company Loan Program (504) Certification Procedures to Become A Cdc § 120.812 Probationary period for newly certified CDCs. (a) Newly certified CDCs will be on probation for a period of two...

  7. 13 CFR 120.812 - Probationary period for newly certified CDCs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... certified CDCs. 120.812 Section 120.812 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development Company Loan Program (504) Certification Procedures to Become A Cdc § 120.812 Probationary period for newly certified CDCs. (a) Newly certified CDCs will be on probation for a period of two...

  8. 13 CFR 120.812 - Probationary period for newly certified CDCs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... certified CDCs. 120.812 Section 120.812 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development Company Loan Program (504) Certification Procedures to Become A Cdc § 120.812 Probationary period for newly certified CDCs. (a) Newly certified CDCs will be on probation for a period of two...

  9. 13 CFR 120.812 - Probationary period for newly certified CDCs.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... certified CDCs. 120.812 Section 120.812 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION BUSINESS LOANS Development Company Loan Program (504) Certification Procedures to Become A Cdc § 120.812 Probationary period for newly certified CDCs. (a) Newly certified CDCs will be on probation for a period of two...

  10. 47 CFR 15.202 - Certified operating frequency range.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Certified operating frequency range. 15.202 Section 15.202 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Intentional Radiators § 15.202 Certified operating frequency range. Client devices that operate in a master...

  11. Study on the ownership balance and the efficiency of mixed ownership enterprises from the perspective of heterogeneous shareholders

    PubMed Central

    Yin, Zhujia; Liu, Lijuan; Wang, Haidong

    2018-01-01

    Based on the database data of Chinese industrial enterprises from 2000 to 2007 and the LP method, this paper measures the total factor productivity of enterprises and investigates the effect of different mixed ownership forms on enterprises’ efficiency and the effect of heterogeneous ownership balance on the mixed ownership enterprises’ efficiency. The state-owned enterprise and mixed ownership enterprise are identified by the enterprise’s paid-up capital. The results show that, on the whole, for the mixed ownership enterprise, the higher the diversification degree of the shareholders is, the higher the efficiency becomes, and in different types of industries, the mixed forms of shareholders have different effects on the efficiency of enterprises. The heterogeneous ownership balance and the enterprise efficiency show nonlinear U-type relationships. Both the higher and lower heterogeneous ownership balance degrees will promote the enterprise’s efficiency. However, when the ownership balance degree is in the range of [0.2 0.5], the increase in ownership balance will lead to the decline of enterprise efficiency. Therefore, when introducing non-state-owned capital, state-owned enterprises should take full account of their own characteristics by rationally controlling the shareholding ratio of non-state-owned capital and play the positive role of a mixed ownership structure in corporate governance with appropriate ownership balances. PMID:29614126

  12. 26 CFR 1.951-1 - Amounts included in gross income of United States shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... pro rata to its shareholders an amount which bears the same ratio to its subpart F income for such... ratio to the subpart F income of such corporation for the taxable year as the part of such year during... by B 15 (ii) B's pro rata share of the amount which bears the same ratio to M Corporation's subpart F...

  13. Two Approaches to Curriculum Development for Educating for Sustainability and CSR

    ERIC Educational Resources Information Center

    Stubbs, Wendy; Schapper, Jan

    2011-01-01

    Purpose: The purpose of this paper is to report on efforts to develop two stand-alone subjects on sustainability and corporate social responsibility (CSR) in a mainstream business curriculum at Monash University, Australia. Design/methodology/approach: This paper presents details on the educational rationale and design of the two subjects in…

  14. 76 FR 80741 - TRICARE: Certified Mental Health Counselors

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-27

    ...] TRICARE: Certified Mental Health Counselors AGENCY: Office of the Secretary, Department of Defense. ACTION... would allow licensed or certified mental health counselors to be able to independently provide care to... health counselors (MHCs) are authorized to practice only with physician referral and supervision. This...

  15. 33 CFR 159.17 - Changes to certified devices.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 2 2011-07-01 2011-07-01 false Changes to certified devices. 159.17 Section 159.17 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) POLLUTION MARINE SANITATION DEVICES Certification Procedures § 159.17 Changes to certified...

  16. 42 CFR 414.54 - Payment for certified nurse-midwives' services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Payment for certified nurse-midwives' services. 414... Physicians and Other Practitioners § 414.54 Payment for certified nurse-midwives' services. For services...)(1)(K) of the Act for the payment of certified nurse-midwife services may not exceed 65 percent of...

  17. 42 CFR 414.54 - Payment for certified nurse-midwives' services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Payment for certified nurse-midwives' services. 414... Physicians and Other Practitioners § 414.54 Payment for certified nurse-midwives' services. (a) For services...)(1)(K) of the Act for the payment of certified nurse-midwife services may not exceed 65 percent of...

  18. 36 CFR 61.6 - Certified local government programs.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Certified local government... INTERIOR PROCEDURES FOR STATE, TRIBAL, AND LOCAL GOVERNMENT HISTORIC PRESERVATION PROGRAMS § 61.6 Certified local government programs. (a) Each approved State program must provide a mechanism for certification...

  19. 36 CFR 61.6 - Certified local government programs.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Certified local government... INTERIOR PROCEDURES FOR STATE, TRIBAL, AND LOCAL GOVERNMENT HISTORIC PRESERVATION PROGRAMS § 61.6 Certified local government programs. (a) Each approved State program must provide a mechanism for certification...

  20. 7 CFR 766.114 - State-certified mediation or voluntary meeting of creditors.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false State-certified mediation or voluntary meeting of... Programs § 766.114 State-certified mediation or voluntary meeting of creditors. (a) A borrower who is...) State-certified mediation; or (2) Voluntary meeting of creditors when a State does not have a certified...

  1. The Impact of Mentoring on Alternatively Certified Teachers

    ERIC Educational Resources Information Center

    Kesler, Becky

    2013-01-01

    The purpose of this study was to explore the perceived effectiveness of mentoring for teachers certified through non-traditional avenues. This quantitative study investigated the type and amount of support teachers certified through the Arkansas Non-traditional Licensure Program (NTLP) and the Master of Arts in Teaching Program (MATP) received…

  2. 12 CFR 1253.6 - Certifying and nullifying an approval.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... this paragraph, an Enterprise's authority to offer a new product or engage in a new activity by reason... PRODUCTS § 1253.6 Certifying and nullifying an approval. (a) An Enterprise shall certify, through an...

  3. An Analysis of a District-Led Leadership Seminar on the Dispositions of Certified Staff Members

    ERIC Educational Resources Information Center

    Rupprecht, Michael J.

    2013-01-01

    The purpose of this study was to determine whether or not a district-led, grow-your-own leadership seminar had a significant impact on the dispositions of its members compared to staff members who did not participate in the program. The participants involved (N = 20) included a naturally formed group of certified staff members (n = 10) who…

  4. 12 CFR 563.43 - Loans by savings associations to their executive officers, directors and principal shareholders.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Loans by savings associations to their... § 563.43 Loans by savings associations to their executive officers, directors and principal shareholders...) that is a savings and loan holding company. A company has control over a saving association if it...

  5. 43 CFR 44.23 - How does the Department certify payment computations?

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Certified Public Accountant, or an independent public accountant, that the statement has been audited in... guidelines that State auditors, independent Certified Public Accountants, or independent public accountants... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How does the Department certify payment...

  6. Financing of certified centers: a willingness-to-pay analysis.

    PubMed

    Thiel, Falk C; Scharl, Anton; Hildebrandt, Thomas; Kotziabassis, Efstratios; Schrauder, Michael G; Bani, Mayada R; Müller, Andreas; Hauzenberger, Tanja; Loehberg, Christian R; Jud, Sebastian M; Fasching, Peter A; Hartmann, Arndt; Schulz-Wendtland, Rüdiger; Strnad, Vratislav; Beckmann, Matthias W; Lux, Michael Patrick

    2013-03-01

    Although care in certified breast centers is now established throughout Germany, numerous services are still not being reimbursed. This also affects other centers involved in the specialty of gynecology such as gynecological cancer centers, perinatal centers, and endometriosis centers. Although a certified center is entitled to charge additional fees, these are in most cases not reimbursed. Calculation of additional costs is limited by the fact that data from the Institute for the Hospital Reimbursement System (Institut für das Entgeltsystem im Krankenhaus, InEK) do not reflect interdisciplinary services and procedures. For decision-makers, society's willingness to pay is an important factor in guiding decisions on the basis of social priorities. A hypothetical maximum willingness to pay can be calculated using a willingness-to-pay analysis, making it possible to identify deficiencies in the arbitrary setting of health budgets at the macro-level. In a multicenter study conducted between November 2009 and December 2010, 2,469 patients at a university hospital and at a non-university hospital were asked about the extent of their awareness of certified centers, the influence of centers on hospital presentation, and about personal attitudes toward quality-oriented reimbursement. A subjective assessment of possible additional charges was calculated using a willingness-to-pay analysis. In the overall group, 53.4 % of the patients were aware of what a certified center is and 27.4 % had specific information (obstetrics 40.0/32.3 %; mastology 66.8/23.2 %; gynecological oncology 54.7/27.3 %; P < 0.001). For 43.8 %, a certified center was one reason or the major reason for presentation (obstetrics 26.2 %; mastology 66.8 %; gynecological oncology 46.6 %; P < 0.001). A total of 72.6 % were in favor of quality-oriented reimbursement and 69.7 % were in favor of an additional charge for a certified center amounting to €538.56 (mastology €643.65, obstetrics €474

  7. 42 CFR 410.77 - Certified nurse-midwives' services: Qualifications and conditions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Certified nurse-midwives' services: Qualifications... Medical and Other Health Services § 410.77 Certified nurse-midwives' services: Qualifications and conditions. (a) Qualifications. For Medicare coverage of his or her services, a certified nurse-midwife must...

  8. 42 CFR 410.77 - Certified nurse-midwives' services: Qualifications and conditions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Certified nurse-midwives' services: Qualifications... Medical and Other Health Services § 410.77 Certified nurse-midwives' services: Qualifications and conditions. (a) Qualifications. For Medicare coverage of his or her services, a certified nurse-midwife must...

  9. 9 CFR 149.5 - Offsite identification and segregation of certified swine.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... of certified swine. 149.5 Section 149.5 Animals and Animal Products ANIMAL AND PLANT HEALTH... § 149.5 Offsite identification and segregation of certified swine. Certified swine moved from a..., collection point, or slaughter facility, must remain segregated from noncertified swine at all times and...

  10. 9 CFR 149.5 - Offsite identification and segregation of certified swine.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... of certified swine. 149.5 Section 149.5 Animals and Animal Products ANIMAL AND PLANT HEALTH... § 149.5 Offsite identification and segregation of certified swine. Certified swine moved from a..., collection point, or slaughter facility, must remain segregated from noncertified swine at all times and...

  11. 9 CFR 149.5 - Offsite identification and segregation of certified swine.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... of certified swine. 149.5 Section 149.5 Animals and Animal Products ANIMAL AND PLANT HEALTH... § 149.5 Offsite identification and segregation of certified swine. Certified swine moved from a..., collection point, or slaughter facility, must remain segregated from noncertified swine at all times and...

  12. 9 CFR 149.5 - Offsite identification and segregation of certified swine.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... of certified swine. 149.5 Section 149.5 Animals and Animal Products ANIMAL AND PLANT HEALTH... § 149.5 Offsite identification and segregation of certified swine. Certified swine moved from a..., collection point, or slaughter facility, must remain segregated from noncertified swine at all times and...

  13. 9 CFR 149.5 - Offsite identification and segregation of certified swine.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... of certified swine. 149.5 Section 149.5 Animals and Animal Products ANIMAL AND PLANT HEALTH... § 149.5 Offsite identification and segregation of certified swine. Certified swine moved from a..., collection point, or slaughter facility, must remain segregated from noncertified swine at all times and...

  14. Occupational safety and health aspects of corporate social responsibility (CSR) in Japanese companies listed on the Tokyo Stock Exchange (TSE) first section.

    PubMed

    Kawashita, Futoshi; Taniyama, Yukari; Hwi, Song You; Fujisaki, Takeshi; Kameda, Takashi; Mori, Koji

    2005-11-01

    Recently, corporate social responsibility (CSR) is becoming widely recognized as an issue for Japanese companies. Corporate responsibility for employees is considered important by various stakeholders, and occupational safety and health is regarded as one of these responsibilities. The present authors examined this issue from the viewpoint of corporate management by analysis of statements found in CSR-related reports. For companies listed on the First Section of the Tokyo Stock Exchange (TSE), we searched for CSR-related reports, and titles and contents, based on two established guidelines: the GRI Sustainability Reporting Guidelines 2002 as the international reference and the Environmental Reporting Guidelines of the Ministry of the Environment, Government of Japan, as the domestic reference. Corporations that published CSR reports were 26.3% (416/1,581) of the total, and large differences were recognized by type of industry. Comparing the numbers of pages for various contents, more concern was shown about the environment than about social activity, indicating the environment to be the main issue of CSR in Japan. In the items included in the guidelines, many matters about occupational accidents were mentioned, but it was found that statements regarding HIV/AIDS, which is not of such strong social concern in Japan, and statements regarding the costs of safety that are difficult to calculate were few. However, statements regarding mental health, which is of high interest socially, were many, even though this issue is not included in the two guidelines used. In revising the guidelines, these matters should be reviewed. In the future, continuance of analysis of CSR-related reports with regard to changes and comparisons with overseas reports will help improve occupational safety and health.

  15. [Development of the certified reference material of mercury in lyophilized human urine].

    PubMed

    Zhao, Wei; Zhang, Fu-gang; DU, Hui-fang; Pan, Ya-juan; Yan, Hui-fang

    2011-02-01

    To develop the certified reference material of mercury in lyophilized human urine. Human urine samples from normal level mercury districts were filtered, homogenized, dispensed, lyophilized and radio-sterilized. Homogeneity test, stability inspection and certification were conducted using a atom fluorescence spectrophotometric method. The physical and chemical stability of the certified reference material were assessed for 18 months. The certified values are based on analysis made by three independent laboratories. The certified values are as follows: low level was (35.6 ± 2.1) µg/L, high level was (50.5 ± 3.0) µg/L. The certified reference material of mercury in lyophilized human urine in this research reached the national certified reference material requirements and could be used for the quality control.

  16. 7 CFR 201.74 - Labeling of all classes of certified seed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 3 2011-01-01 2011-01-01 false Labeling of all classes of certified seed. 201.74... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.74 Labeling of all classes of certified seed. (a...

  17. 7 CFR 201.74 - Labeling of all classes of certified seed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Labeling of all classes of certified seed. 201.74... SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.74 Labeling of all classes of certified seed. (a...

  18. Bright luminescence of Vibrio fischeri aconitase mutants reveals a connection between citrate and the Gac/Csr regulatory system.

    PubMed

    Septer, Alecia N; Bose, Jeffrey L; Lipzen, Anna; Martin, Joel; Whistler, Cheryl; Stabb, Eric V

    2015-01-01

    The Gac/Csr regulatory system is conserved throughout the γ-proteobacteria and controls key pathways in central carbon metabolism, quorum sensing, biofilm formation and virulence in important plant and animal pathogens. Here we show that elevated intracellular citrate levels in a Vibrio fischeri aconitase mutant correlate with activation of the Gac/Csr cascade and induction of bright luminescence. Spontaneous or directed mutations in the gene that encodes citrate synthase reversed the bright luminescence of aconitase mutants, eliminated their citrate accumulation and reversed their elevated expression of CsrB. Our data elucidate a correlative link between central metabolic and regulatory pathways, and they suggest that the Gac system senses a blockage at the aconitase step of the tricarboxylic acid cycle, either through elevated citrate levels or a secondary metabolic effect of citrate accumulation, and responds by modulating carbon flow and various functions associated with host colonization, including bioluminescence. © 2014 John Wiley & Sons Ltd.

  19. 26 CFR 1.1291-0 - Treatment of shareholders of certain passive foreign investment companies; table of contents.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 26 Internal Revenue 11 2011-04-01 2011-04-01 false Treatment of shareholders of certain passive... passive foreign investment companies; table of contents. This section contains a listing of the headings...) Former PFIC. (j) Definitions. (1) Passive foreign investment company (PFIC). (2) Types of PFICs. (i...

  20. Diagnosis of poor safety culture as a major shortcoming in OHSAS 18001-certified companies.

    PubMed

    Ghahramani, Abolfazl

    2017-04-07

    The evaluation of safety performance in occupational health and safety assessment series (OHSAS) 18001-certified companies provides useful information about the quality of the management system. A certified organization should employ an adequate level of safety management and a positive safety culture to achieve a satisfactory safety performance. The present study conducted in six manufacturing companies: three OHSAS 18001-certified, and three non-certified to assess occupational health and safety (OHS) as well as OHSAS 18001 practices. The certified companies had a better OHS practices compared with the non-certified companies. The certified companies slightly differed in OHS and OHSAS 18001 practices and one of the certified companies had the highest activity rates for both practices. The results indicated that the implemented management systems have not developed and been maintained appropriately in the certified companies. The in-depth analysis of the collected evidence revealed shortcomings in safety culture improvement in the certified companies. This study highlights the importance of safety culture to continuously improve the quality of OHSAS 18001 and to properly perform OHS/OHSAS 18001 practices in the certified companies.

  1. Diagnosis of poor safety culture as a major shortcoming in OHSAS 18001-certified companies

    PubMed Central

    GHAHRAMANI, Abolfazl

    2016-01-01

    The evaluation of safety performance in occupational health and safety assessment series (OHSAS) 18001-certified companies provides useful information about the quality of the management system. A certified organization should employ an adequate level of safety management and a positive safety culture to achieve a satisfactory safety performance. The present study conducted in six manufacturing companies: three OHSAS 18001-certified, and three non-certified to assess occupational health and safety (OHS) as well as OHSAS 18001 practices. The certified companies had a better OHS practices compared with the non-certified companies. The certified companies slightly differed in OHS and OHSAS 18001 practices and one of the certified companies had the highest activity rates for both practices. The results indicated that the implemented management systems have not developed and been maintained appropriately in the certified companies. The in-depth analysis of the collected evidence revealed shortcomings in safety culture improvement in the certified companies. This study highlights the importance of safety culture to continuously improve the quality of OHSAS 18001 and to properly perform OHS/OHSAS 18001 practices in the certified companies. PMID:28025422

  2. Certified Athletic Trainers as Certified Teachers: A Model for Making It Happen

    ERIC Educational Resources Information Center

    Unruh, Nita; Unruh, Scott; Scantling, Ed

    2008-01-01

    School administrators don't usually consider hiring a certified athletic trainer for managing the medical issues that arise from students' participation in athletics, perhaps because they believe it would be too expensive to hire someone solely to manage injury and illness for just a portion of the students. Since it is important to provide…

  3. Lon protease modulates virulence traits in Erwinia amylovora by direct monitoring of major regulators and indirectly through the Rcs and Gac-Csr regulatory systems.

    PubMed

    Lee, Jae Hoon; Ancona, Veronica; Zhao, Youfu

    2018-04-01

    Lon, an ATP-dependent protease in bacteria, influences diverse cellular processes by degrading damaged, misfolded and short-lived regulatory proteins. In this study, we characterized the effects of lon mutation and determined the molecular mechanisms underlying Lon-mediated virulence regulation in Erwinia amylovora, an enterobacterial pathogen of apple. Erwinia amylovora depends on the type III secretion system (T3SS) and the exopolysaccharide (EPS) amylovoran to cause disease. Our results showed that mutation of the lon gene led to the overproduction of amylovoran, increased T3SS gene expression and the non-motile phenotype. Western blot analyses showed that mutation in lon directly affected the accumulation and stability of HrpS/HrpA and RcsA. Mutation in lon also indirectly influenced the expression of flhD, hrpS and csrB through the accumulation of the RcsA/RcsB proteins, which bind to the promoter of these genes. In addition, lon expression is under the control of CsrA, possibly at both the transcriptional and post-transcriptional levels. Although mutation in csrA abolished both T3SS and amylovoran production, deletion of the lon gene in the csrA mutant only rescued amylovoran production, but not T3SS. These results suggest that CsrA might positively control both T3SS and amylovoran production partly by suppressing Lon, whereas CsrA may also play a critical role in T3SS by affecting unknown targets. © 2017 BSPP AND JOHN WILEY & SONS LTD.

  4. A Case Study of the Partnership Schools Comprehensive School Reform (CSR) Model

    ERIC Educational Resources Information Center

    Epstein, Joyce L.

    2005-01-01

    This case study reports the feasibility of the Partnership Schools Comprehensive School Reform (CSR) model for school improvement in a Title I elementary school. Interviews were conducted and documents were collected for 3 years to study whether and how the school implemented key policy attributes--specificity, consistency, authority, power, and…

  5. 76 FR 28403 - National Registry of Certified Medical Examiners

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ... [Docket No. FMCSA-2008-0363] RIN 2126-AA97 National Registry of Certified Medical Examiners ACTION: Notice... by training providers in implementing the National Registry of Certified Medical Examiners (National... included minimum training requirements for medical examiners. The draft guidance announced by this notice...

  6. Synthesizing Certified Code

    NASA Technical Reports Server (NTRS)

    Whalen, Michael; Schumann, Johann; Fischer, Bernd

    2002-01-01

    Code certification is a lightweight approach to demonstrate software quality on a formal level. Its basic idea is to require producers to provide formal proofs that their code satisfies certain quality properties. These proofs serve as certificates which can be checked independently. Since code certification uses the same underlying technology as program verification, it also requires many detailed annotations (e.g., loop invariants) to make the proofs possible. However, manually adding theses annotations to the code is time-consuming and error-prone. We address this problem by combining code certification with automatic program synthesis. We propose an approach to generate simultaneously, from a high-level specification, code and all annotations required to certify generated code. Here, we describe a certification extension of AUTOBAYES, a synthesis tool which automatically generates complex data analysis programs from compact specifications. AUTOBAYES contains sufficient high-level domain knowledge to generate detailed annotations. This allows us to use a general-purpose verification condition generator to produce a set of proof obligations in first-order logic. The obligations are then discharged using the automated theorem E-SETHEO. We demonstrate our approach by certifying operator safety for a generated iterative data classification program without manual annotation of the code.

  7. Doing well while fighting river blindness: the alignment of a corporate drug donation programme with responsibilities to shareholders.

    PubMed

    Hernando, Yolanda; Colwell, Kaela; Wright, Brian D

    2016-10-01

    Using the example of Merck's donations of ivermectin, to show how tax incentives and non-profit collaborators can make corporate largesse consistent with obligations to maximise returns to shareholders. We obtained information from publicly available data and estimated Merck's tax deductions according to the US Internal Revenue Code. Reviews of Merck-Kitasato contracts and personal interviews provided additional information regarding key lessons from this collaboration. Our best estimate of the direct cost to Merck of the ivermectin tablets donated during 2005-2011 is around US$ 600 million, well below the stated value of US$ 3.8 billion. Our calculation of tax write-offs reduces the net cost to around US$ 180 million in that period. Indirect market benefits and effects on goodwill further enhanced the compatibility of Merck's donation programme with the company's profit-maximising objective. The case offers lessons for effective management of collaborations with public and non-profit organisations. Merck's role in the donation of ivermectin for the treatment of onchocerciasis is widely and justly acknowledged as a prime example of corporate largesse in the public interest. It is nevertheless important to note that several public and non-profit collaborators, and United States taxpayers, played significant roles in increasing Merck's incentives, and indeed ability, to conduct the donation programme that changed so many lives in poor countries, while meeting its responsibilities to shareholders. Overall, the record indicates responsible corporate management of Merck's ivermectin programme and demonstrates the feasibility of socially responsible policies in a manner compatible with obligations to shareholders. © 2016 John Wiley & Sons Ltd.

  8. 7 CFR 762.106 - Preferred and certified lender programs.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Preferred and certified lender programs. 762.106 Section 762.106 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.106 Preferred and certified lender...

  9. 7 CFR 762.106 - Preferred and certified lender programs.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Preferred and certified lender programs. 762.106 Section 762.106 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS GUARANTEED FARM LOANS § 762.106 Preferred and certified lender...

  10. High-frequency signal and noise estimates of CSR GRACE RL04

    NASA Astrophysics Data System (ADS)

    Bonin, Jennifer A.; Bettadpur, Srinivas; Tapley, Byron D.

    2012-12-01

    A sliding window technique is used to create daily-sampled Gravity Recovery and Climate Experiment (GRACE) solutions with the same background processing as the official CSR RL04 monthly series. By estimating over shorter time spans, more frequent solutions are made using uncorrelated data, allowing for higher frequency resolution in addition to daily sampling. Using these data sets, high-frequency GRACE errors are computed using two different techniques: assuming the GRACE high-frequency signal in a quiet area of the ocean is the true error, and computing the variance of differences between multiple high-frequency GRACE series from different centers. While the signal-to-noise ratios prove to be sufficiently high for confidence at annual and lower frequencies, at frequencies above 3 cycles/year the signal-to-noise ratios in the large hydrological basins looked at here are near 1.0. Comparisons with the GLDAS hydrological model and high frequency GRACE series developed at other centers confirm CSR GRACE RL04's poor ability to accurately and reliably measure hydrological signal above 3-9 cycles/year, due to the low power of the large-scale hydrological signal typical at those frequencies compared to the GRACE errors.

  11. Digging Deep for Meaning: A Critical Hermeneutic Analysis of CEO Letters to Shareholders in the Oil Industry.

    ERIC Educational Resources Information Center

    Prasad, Anshuman; Mir, Raza

    2002-01-01

    Uses the methodology of critical hermeneutics to analyze Chief Executive Officers' letters to shareholders in the United States petroleum industry during the 1970s and 1980s. Suggests these letters were deployed to produce a certain attitude toward OPEC (Organization of Petroleum Exporting Countries) among their readers that deflected attention of…

  12. Dynamic Mechanical Properties and Fracture Surface Morphologies of Core-Shell Rubber (CSR) Toughened Epoxy at Liquid Nitrogen (Ln2) Temperatures

    NASA Technical Reports Server (NTRS)

    Wang, J.; Magee, D.; Schneider, J. A.

    2009-01-01

    The dynamic mechanical properties and fracture surface morphologies were evaluated for a commercial epoxy resin toughened with two types of core-shell rubber (CSR) toughening agents (Kane Ace(Registered TradeMark) MX130 and MX960). The impact resistance (R) was evaluated by the resulting breaking energy measured in Charpy impact tests conducted on an instrumented drop tower. The resulting fracture surface morphologies were examined using Scanning Electron Microscopy (SEM). Fractographic observations of the CSR toughened epoxy tested at ambient temperature, showed a fracture as characterized by slender dendrite textures with large voids. The increasing number of dendrites and decreasing size of scale-like texture with more CSR particles corresponded with increased R. As the temperature decreased to Liquid Nitrogen (LN 2), the fracture surfaces showed a fracture characterized by a rough, torn texture containing many river markings and deep furrows.

  13. 7 CFR 1280.103 - Certified organization.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE LAMB PROMOTION, RESEARCH, AND INFORMATION ORDER Lamb Promotion, Research, and Information Order Definitions § 1280.103 Certified...

  14. 10 CFR 504.9 - Environmental requirements for certifying powerplants.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ....9 Section 504.9 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS § 504.9... use of natural gas or petroleum, or both, as a primary energy source in any certifying powerplant... fuel as a primary energy source in a certifying powerplant. (a) NEPA compliance. Except as provided in...

  15. 10 CFR 504.9 - Environmental requirements for certifying powerplants.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ....9 Section 504.9 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS § 504.9... use of natural gas or petroleum, or both, as a primary energy source in any certifying powerplant... fuel as a primary energy source in a certifying powerplant. (a) NEPA compliance. Except as provided in...

  16. 10 CFR 504.9 - Environmental requirements for certifying powerplants.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ....9 Section 504.9 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS § 504.9... use of natural gas or petroleum, or both, as a primary energy source in any certifying powerplant... fuel as a primary energy source in a certifying powerplant. (a) NEPA compliance. Except as provided in...

  17. 10 CFR 504.9 - Environmental requirements for certifying powerplants.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ....9 Section 504.9 Energy DEPARTMENT OF ENERGY (CONTINUED) ALTERNATE FUELS EXISTING POWERPLANTS § 504.9... use of natural gas or petroleum, or both, as a primary energy source in any certifying powerplant... fuel as a primary energy source in a certifying powerplant. (a) NEPA compliance. Except as provided in...

  18. 40 CFR 85.1407 - Notification of intent to certify.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Urban Bus Rebuild Requirements § 85.1407... certifier that use of its certified equipment will not cause a substantial increase to urban bus engine... § 85.1403(b) for all affected urban bus operators as specified in § 85.1401, the notification shall...

  19. 40 CFR 85.1407 - Notification of intent to certify.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Urban Bus Rebuild Requirements § 85.1407... certifier that use of its certified equipment will not cause a substantial increase to urban bus engine... § 85.1403(b) for all affected urban bus operators as specified in § 85.1401, the notification shall...

  20. 40 CFR 85.1407 - Notification of intent to certify.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Urban Bus Rebuild Requirements § 85.1407... certifier that use of its certified equipment will not cause a substantial increase to urban bus engine... § 85.1403(b) for all affected urban bus operators as specified in § 85.1401, the notification shall...

  1. 40 CFR 85.1407 - Notification of intent to certify.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) CONTROL OF AIR POLLUTION FROM MOBILE SOURCES Urban Bus Rebuild Requirements § 85.1407... certifier that use of its certified equipment will not cause a substantial increase to urban bus engine... § 85.1403(b) for all affected urban bus operators as specified in § 85.1401, the notification shall...

  2. 26 CFR 1.956-1 - Shareholder's pro rata share of a controlled foreign corporation's increase in earnings invested...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... controlled foreign corporation's investment of earnings in United States property—(1) Dividend limitation... foreign corporation's increase in earnings invested in United States property. 1.956-1 Section 1.956-1...) INCOME TAXES Controlled Foreign Corporations § 1.956-1 Shareholder's pro rata share of a controlled...

  3. ENERGY STAR Certified Vending Machines

    EPA Pesticide Factsheets

    Certified models meet all ENERGY STAR requirements as listed in the Version 3.0 ENERGY STAR Program Requirements for Refrigerated Beverage Vending Machines that are effective as of March 1, 2013. A detailed listing of key efficiency criteria are available at

  4. 76 FR 14366 - National Registry of Certified Medical Examiners

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-16

    ... [Docket No. FMCSA-2008-0363] RIN 2126-AA97 National Registry of Certified Medical Examiners AGENCY... Certified Medical Examiners (NRCME) published on December 1, 2008. In the comments on the NPRM, a commenter inquired as to what a motor carrier had to do to verify that a medical examiner's certificate had been...

  5. 42 CFR 441.153 - Team certifying need for services.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 4 2013-10-01 2013-10-01 false Team certifying need for services. 441.153 Section... § 441.153 Team certifying need for services. Certification under § 441.152 must be made by terms..., certification must be made by an independent team that— (1) Includes a physician; (2) Has competence in...

  6. 42 CFR 441.153 - Team certifying need for services.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 4 2011-10-01 2011-10-01 false Team certifying need for services. 441.153 Section... § 441.153 Team certifying need for services. Certification under § 441.152 must be made by terms..., certification must be made by an independent team that— (1) Includes a physician; (2) Has competence in...

  7. 42 CFR 441.153 - Team certifying need for services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 4 2014-10-01 2014-10-01 false Team certifying need for services. 441.153 Section... § 441.153 Team certifying need for services. Certification under § 441.152 must be made by terms..., certification must be made by an independent team that— (1) Includes a physician; (2) Has competence in...

  8. 42 CFR 441.153 - Team certifying need for services.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 4 2012-10-01 2012-10-01 false Team certifying need for services. 441.153 Section... § 441.153 Team certifying need for services. Certification under § 441.152 must be made by terms..., certification must be made by an independent team that— (1) Includes a physician; (2) Has competence in...

  9. 42 CFR 441.153 - Team certifying need for services.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Team certifying need for services. 441.153 Section... § 441.153 Team certifying need for services. Certification under § 441.152 must be made by terms..., certification must be made by an independent team that— (1) Includes a physician; (2) Has competence in...

  10. The lamaze certified childbirth educator: standards of practice.

    PubMed

    Lothian, Judith A

    2007-01-01

    A student in a Lamaze Childbirth Educator Program expresses concern that some Lamaze Certified Childbirth Educators (LCCE educators) do not teach classes that reflect Lamaze standards. In this column, the ethical and professional standards of the LCCE educator and the challenges the childbirth educator experiences while practicing in the current maternity-care environment are presented and discussed. Lamaze International's Code of Ethics for Lamaze Certified Childbirth Educators provides guidance when dealing with these challenges.

  11. About the EPA Plan to Certify Applicators in Indian Country

    EPA Pesticide Factsheets

    Restricted use pesticides (RUPs) require special care to avoid harming human health or the environment. They can only be sold to or used by certified applicators. The EPA Plan applies to certified applicators who intend to apply RUPs in Indian Country.

  12. 43 CFR 44.23 - How does the Department certify payment computations?

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Certified Public Accountant, or an independent public accountant, that the statement has been audited in... guidelines that State auditors, independent Certified Public Accountants, or independent public accountants...

  13. 43 CFR 44.23 - How does the Department certify payment computations?

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Certified Public Accountant, or an independent public accountant, that the statement has been audited in... guidelines that State auditors, independent Certified Public Accountants, or independent public accountants...

  14. 43 CFR 44.23 - How does the Department certify payment computations?

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Certified Public Accountant, or an independent public accountant, that the statement has been audited in... guidelines that State auditors, independent Certified Public Accountants, or independent public accountants...

  15. 43 CFR 44.23 - How does the Department certify payment computations?

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Certified Public Accountant, or an independent public accountant, that the statement has been audited in... guidelines that State auditors, independent Certified Public Accountants, or independent public accountants...

  16. 40 CFR 60.1685 - What if all the certified operators must be temporarily offsite?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... onsite. (2) Submit a status report and corrective action summary to the Administrator every 4 weeks... hours, but for 2 weeks or less, and no other certified operator is onsite, the provisionally certified... weeks, and no other certified operator is onsite, the provisionally certified control room operator may...

  17. The Lamaze Certified Childbirth Educator: Standards of Practice

    PubMed Central

    Lothian, Judith A.

    2007-01-01

    A student in a Lamaze Childbirth Educator Program expresses concern that some Lamaze Certified Childbirth Educators (LCCE educators) do not teach classes that reflect Lamaze standards. In this column, the ethical and professional standards of the LCCE educator and the challenges the childbirth educator experiences while practicing in the current maternity-care environment are presented and discussed. Lamaze International's Code of Ethics for Lamaze Certified Childbirth Educators provides guidance when dealing with these challenges. PMID:18408808

  18. A comparison of certified and noncertified pet foods.

    PubMed

    Brown, R G

    1997-11-01

    The market presents the buyer with a wide array of pet food choices. Marketing pet foods has changed in the last decade and today foods may be bought at a variety of outlets. The present study compares nutrient composition, digestibility, and effect on urine pH (cat foods only) of selected certified and noncertified pet foods from different outlets. The selected foods were considered analogous in terms of declared ingredients and macronutrient profiles. The analytical methods used were those of the Association of Official Analytical Chemists as described in the Pet Food Certification Protocol of the Canadian Veterinary Medical Association. The test foods were sampled 4 times from August 1994 to July 1995. Both certified and noncertified products met the nutritional requirements on a consistent basis, although 1 of the noncertified dog foods consistently failed to meet the zinc requirements. This same product also failed to meet the Canadian Veterinary Medical Association's standards for concentrations of protein, calcium, and phosphorus. One of the noncertified cat foods failed to meet the recommended calcium level. With the exception of fat digestion in 1 noncertified food, there were no statistically significant differences in major nutrient digestibility between certified and noncertified pet foods. There were some statistically significant differences in digestibility within both the certified and noncertified groups of foods. The practical significance of any of the statistical differences in digestibility is uncertain. Urine pH observed in cats fed noncertified test diets was variable, with some values greater than 7.0 as a maximum or 6.5 as an average. The general conclusion of this study was that the commonly available certified products were the nutritional equal of those foods that position themselves as "premium."

  19. A comparison of certified and noncertified pet foods.

    PubMed Central

    Brown, R G

    1997-01-01

    The market presents the buyer with a wide array of pet food choices. Marketing pet foods has changed in the last decade and today foods may be bought at a variety of outlets. The present study compares nutrient composition, digestibility, and effect on urine pH (cat foods only) of selected certified and noncertified pet foods from different outlets. The selected foods were considered analogous in terms of declared ingredients and macronutrient profiles. The analytical methods used were those of the Association of Official Analytical Chemists as described in the Pet Food Certification Protocol of the Canadian Veterinary Medical Association. The test foods were sampled 4 times from August 1994 to July 1995. Both certified and noncertified products met the nutritional requirements on a consistent basis, although 1 of the noncertified dog foods consistently failed to meet the zinc requirements. This same product also failed to meet the Canadian Veterinary Medical Association's standards for concentrations of protein, calcium, and phosphorus. One of the noncertified cat foods failed to meet the recommended calcium level. With the exception of fat digestion in 1 noncertified food, there were no statistically significant differences in major nutrient digestibility between certified and noncertified pet foods. There were some statistically significant differences in digestibility within both the certified and noncertified groups of foods. The practical significance of any of the statistical differences in digestibility is uncertain. Urine pH observed in cats fed noncertified test diets was variable, with some values greater than 7.0 as a maximum or 6.5 as an average. The general conclusion of this study was that the commonly available certified products were the nutritional equal of those foods that position themselves as "premium." PMID:9360790

  20. A study of compliance with environmental regulations of ISO 14001 certified companies in Korea.

    PubMed

    Kwon, Dong-Myung; Seo, Min-Seok; Seo, Yong-Chil

    2002-08-01

    This article investigates the impact of ISO 14001 certification on the compliance with environmental regulations by Korean companies. The impact of ISO 14001 certification on the industry was studied through a questionnaire survey and the compliance of environmental regulations were investigated using government-released data. The motivation for an environment management system was a result of the current international situation and the need to maintain fair competition. ISO 14001 certification has been recognized as an essential strategy for industrial competition and to improve company/product recognition. The certified and non-certified companies' environmental regulation violation (ERV) rates were 3.5% and 11.6%, respectively, in 1997. In 1998, the ERV rate had an eight-time difference with 1.0% and 8.5% for certified and non-certified companies, respectively. Annual regulation violation rates were reduced from 3.5% in 1997 to 1.0% in 1998 with certified companies and from 11.6% in 1997 to 8.5% in 1998 with their non-certified counterparts, respectively. ISO 14001 certified companies showed more improvement than non-certified companies in regards to environmental performance.

  1. 77 FR 5415 - National Organic Program: Notice of Draft Guidance for Accredited Certifying Agents, Certified...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-03

    ... in order to be excluded from the organic certification requirements of Part 205. The NOSB recommended... handling operations that are or are not excluded from organic certification. The draft guidance proposes... excluded from certification and, therefore, must be certified organic operations. \\1\\ NOSB Recommendation...

  2. Astrochemistry in TSR and CSR Ion Storage Rings

    NASA Astrophysics Data System (ADS)

    Novotny, Oldrich

    2017-04-01

    Dissociative recombination (DR) of molecular ions plays a key role in controlling the charge density and composition of the cold interstellar medium (ISM). Experimental data on DR are required in order to understand the chemical network in the ISM and related processes such as star formation from molecular clouds. Needed data include not only total reaction cross sections, but also the chemical composition and excitation states of the neutral products. Utilizing the TSR storage ring in Heidelberg, Germany, we have carried out DR measurements for astrophysically important molecular ions. We use a merged electron-ion beams technique combined with event-by-event fragment counting and fragment imaging. The count rate of detected neutral DR products yields the absolute DR rate coefficient. Imaging the distribution of fragment distances provides information on the kinetic energy released including the states of both the initial molecule and the final products. Additional kinetic energy sensitivity of the employed detector allows for identification of fragmentation channels by fragment-mass combination within each dissociation event. Such combined information is essential for studies on DR of polyatomic ions with multi-channel breakup. The recently commissioned Cryogenic Storage Ring (CSR) in Heidelberg, Germany, extends the experimental capabilities of TSR by operation at cryogenic temperatures down to 6 K. At these conditions residual gas densities down to 100 cm-3 can be reached resulting in beam storage times of several hours. Long storage in the cold environment allows the ions to relax down to their rotational ground state, thus mimicking well the conditions in the cold ISM. A variety of astrophysically relevant reactions will be investigated at these conditions, such as DR, electron impact excitation, ion-neutral collisions, etc. We report our TSR results on DR of HCl+ and D2Cl+. We also present first results from the CSR commissioning experiments.

  3. 78 FR 79010 - Criteria to Certify Coal Mine Rescue Teams

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-27

    ... to Certify Coal Mine Rescue Teams AGENCY: Mine Safety and Health Administration, Labor. ACTION... updated the coal mine rescue team certification criteria. The Mine Improvement and New Emergency Response... mine operator to certify the qualifications of a coal mine rescue team is that team members are...

  4. 29 CFR 2509.08-2 - Interpretive bulletin relating to the exercise of shareholder rights and written statements of...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., fiduciaries also need to take into account costs when deciding whether and how to exercise their shareholder... into account in determining whether the exercise of such rights (e.g., the voting of a proxy..., statements may need to take into account factors such as the plan's funding policy and its liquidity needs as...

  5. Liability of corporate shareholders and successor corporations for abandoned sites under the Comprehensive Environmental Response, Compensation and Liability Act. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1984-06-13

    The directive identifies legal principles bearing on the extent to which corporate shareholders and successor corporations may be held liable for response costs that arise as a result of a release at a hazardous waste facility.

  6. Teacher Efficacy of Alternative and Traditionally Certified Special Education Teachers

    ERIC Educational Resources Information Center

    Green, Sean Michael

    2012-01-01

    A teacher shortage in the area of special education has led to an increase in the number of alternatively certified special education teachers. Many alternative certification programs focus on content knowledge rather than pedagogical training, allowing many alternatively certified teachers into the classroom with little pedagogical training.…

  7. Global Regulatory Mutations in csrA and rpoS Cause Severe Central Carbon Stress in Escherichia coli in the Presence of Acetate

    PubMed Central

    Wei, Bangdong; Shin, Sooan; LaPorte, David; Wolfe, Alan J.; Romeo, Tony

    2000-01-01

    The csrA gene encodes a small RNA-binding protein, which acts as a global regulator in Escherichia coli and other bacteria (T. Romeo, Mol. Microbiol. 29:1321–1330, 1998). Its key regulatory role in central carbon metabolism, both as an activator of glycolysis and as a potent repressor of glycogen biosynthesis and gluconeogenesis, prompted us to examine the involvement of csrA in acetate metabolism and the tricarboxylic acid (TCA) cycle. We found that growth of csrA rpoS mutant strains was very poor on acetate as a sole carbon source. Surprisingly, growth also was inhibited specifically by the addition of modest amounts of acetate to rich media (e.g., tryptone broth). Cultures grown in the presence of ≥25 mM acetate consisted substantially of glycogen biosynthesis (glg) mutants, which were no longer inhibited by acetate. Several classes of glg mutations were mapped to known and novel loci. Several hypotheses were examined to provide further insight into the effects of acetate on growth and metabolism in these strains. We determined that csrA positively regulates acs (acetyl-coenzyme A synthetase; Acs) expression and isocitrate lyase activity without affecting key TCA cycle enzymes or phosphotransacetylase. TCA cycle intermediates or pyruvate, but not glucose, galactose, or glycerol, restored growth and prevented the glg mutations in the presence of acetate. Furthermore, amino acid uptake was inhibited by acetate specifically in the csrA rpoS strain. We conclude that central carbon flux imbalance, inhibition of amino acid uptake, and a deficiency in acetate metabolism apparently are combined to cause metabolic stress by depleting the TCA cycle. PMID:10692369

  8. 7 CFR 201.73 - Processors and processing of all classes of certified seed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.73 Processors and processing... of certified seed: (a) Facilities shall be available to perform processing without introducing... 7 Agriculture 3 2010-01-01 2010-01-01 false Processors and processing of all classes of certified...

  9. 7 CFR 201.73 - Processors and processing of all classes of certified seed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.73 Processors and processing... of certified seed: (a) Facilities shall be available to perform processing without introducing... 7 Agriculture 3 2011-01-01 2011-01-01 false Processors and processing of all classes of certified...

  10. 7 CFR 201.73 - Processors and processing of all classes of certified seed.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.73 Processors and processing... of certified seed: (a) Facilities shall be available to perform processing without introducing... 7 Agriculture 3 2013-01-01 2013-01-01 false Processors and processing of all classes of certified...

  11. 7 CFR 201.73 - Processors and processing of all classes of certified seed.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.73 Processors and processing... of certified seed: (a) Facilities shall be available to perform processing without introducing... 7 Agriculture 3 2012-01-01 2012-01-01 false Processors and processing of all classes of certified...

  12. 7 CFR 201.73 - Processors and processing of all classes of certified seed.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.73 Processors and processing... of certified seed: (a) Facilities shall be available to perform processing without introducing... 7 Agriculture 3 2014-01-01 2014-01-01 false Processors and processing of all classes of certified...

  13. Farmers’ decision analysis to select certified palm oil seedlings in Lampung, Indonesia

    NASA Astrophysics Data System (ADS)

    Utoyo, Bambang; Yolandika, Clara

    2018-03-01

    This research aimed to analyse (1) decission making process of certified and uncertified palm oil seedlings and (2) factors that influence farmer decision to select certified and uncertified palm oil seedlings. This research was conducted in some districts in Lampung, such as Mesuji, Central Lampung, Tulang Bawang, North Lampung, Way Kanan and South Lampung. The respondents consisted of 30 farmers using certified seeds and 30 farmers using uncertified seeds. The study was conducted from January to May 2017. In addition, factors that influence farmer decision was analysed by logistic regression model. The results showed that decision making on the use of certified or uncertified palm seeds by farmers through the stages: introduction of problems or needs, searching of information, alternative evaluation, purchasing decisions, and post-purchase behaviour. Factors that significantly influence farmer's decision to use certified seeds were land area, seeds price, external influenced, and farmers’ perception.

  14. CsrB, a noncoding regulatory RNA, is required for BarA-dependent expression of biocontrol traits in Rahnella aquatilis HX2.

    PubMed

    Mei, Li; Xu, Sanger; Lu, Peng; Lin, Haiping; Guo, Yanbin; Wang, Yongjun

    2017-01-01

    Rahnella aquatilis is ubiquitous and its certain strains have the applicative potent as a plant growth-promoting rhizobacteria. R. aquatilis HX2 is a biocontrol agent to produce antibacterial substance (ABS) and showed efficient biocontrol against crown gall caused by Agrobacterium vitis on sunflower and grapevine plants. The regulatory network of the ABS production and biocontrol activity is still limited known. In this study, a transposon-mediated mutagenesis strategy was used to investigate the regulators that involved in the biocontrol activity of R. aquatilis HX2. A 366-nt noncoding RNA CsrB was identified in vitro and in vivo, which regulated ABS production and biocontrol activity against crown gall on sunflower plants, respectively. The predicted product of noncoding RNA CsrB contains 14 stem-loop structures and an additional ρ-independent terminator harpin, with 23 characteristic GGA motifs in the loops and other unpaired regions. CsrB is required for ABS production and biocontrol activity in the biocontrol regulation by a two-component regulatory system BarA/UvrY in R. aquatilis HX2. The noncoding RNA CsrB regulates BarA-dependent ABS production and biocontrol activity in R. aquatilis HX2. To the best of our knowledge, this is the first report of noncoding RNA as a regulator for biocontrol function in R. aquatilis.

  15. CsrB, a noncoding regulatory RNA, is required for BarA-dependent expression of biocontrol traits in Rahnella aquatilis HX2

    PubMed Central

    Lu, Peng; Lin, Haiping; Guo, Yanbin

    2017-01-01

    Background Rahnella aquatilis is ubiquitous and its certain strains have the applicative potent as a plant growth-promoting rhizobacteria. R. aquatilis HX2 is a biocontrol agent to produce antibacterial substance (ABS) and showed efficient biocontrol against crown gall caused by Agrobacterium vitis on sunflower and grapevine plants. The regulatory network of the ABS production and biocontrol activity is still limited known. Methodology/Principal findings In this study, a transposon-mediated mutagenesis strategy was used to investigate the regulators that involved in the biocontrol activity of R. aquatilis HX2. A 366-nt noncoding RNA CsrB was identified in vitro and in vivo, which regulated ABS production and biocontrol activity against crown gall on sunflower plants, respectively. The predicted product of noncoding RNA CsrB contains 14 stem-loop structures and an additional ρ-independent terminator harpin, with 23 characteristic GGA motifs in the loops and other unpaired regions. CsrB is required for ABS production and biocontrol activity in the biocontrol regulation by a two-component regulatory system BarA/UvrY in R. aquatilis HX2. Conclusion/Significance The noncoding RNA CsrB regulates BarA-dependent ABS production and biocontrol activity in R. aquatilis HX2. To the best of our knowledge, this is the first report of noncoding RNA as a regulator for biocontrol function in R. aquatilis. PMID:29091941

  16. Get Your Automotive Program Nationally Certified!

    ERIC Educational Resources Information Center

    Lundquist, Patricia A.

    2000-01-01

    Automotive programs that nationally certified enhance student recruitment and give students better employment opportunities. Technicians who earn the Automotive Service Excellence credential have joined the ranks of professionals in the automotive service industry. (Author/JOW)

  17. 26 CFR 1.6035-1 - Returns of U.S. officers, directors and 10-percent shareholders of foreign personal holding...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., together with an explanation of any changes in stock holdings during the taxable year, (ii) The name and... changes in the holdings of such securities during the taxable year, (iii) The name and address of each... corporate, shareholder, and income information for the foreign personal holding company's annual accounting...

  18. 20 CFR 416.804 - Certified copy in lieu of original.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Certified copy in lieu of original. 416.804 Section 416.804 Employees' Benefits SOCIAL SECURITY ADMINISTRATION SUPPLEMENTAL SECURITY INCOME FOR THE AGED, BLIND, AND DISABLED Determination of Age § 416.804 Certified copy in lieu of original. In lieu of...

  19. 7 CFR 201.71 - Establishing the source of all classes of certified seed.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... seed. 201.71 Section 201.71 Agriculture Regulations of the Department of Agriculture (Continued... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.71 Establishing the source of all classes of certified seed. The certifying agency shall have evidence of the class and source of...

  20. 7 CFR 201.71 - Establishing the source of all classes of certified seed.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... seed. 201.71 Section 201.71 Agriculture Regulations of the Department of Agriculture (Continued... (CONTINUED) FEDERAL SEED ACT FEDERAL SEED ACT REGULATIONS Certified Seed § 201.71 Establishing the source of all classes of certified seed. The certifying agency shall have evidence of the class and source of...

  1. 30 CFR 285.705 - When must I use a Certified Verification Agent (CVA)?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... INTERIOR OFFSHORE RENEWABLE ENERGY ALTERNATE USES OF EXISTING FACILITIES ON THE OUTER CONTINENTAL SHELF Facility Design, Fabrication, and Installation Certified Verification Agent § 285.705 When must I use a Certified Verification Agent (CVA)? You must use a CVA to review and certify the Facility Design Report, the...

  2. Research on the relationships of the domestic mutual investment of China based on the cross-shareholding networks of the listed companies

    NASA Astrophysics Data System (ADS)

    Ma, Yuan-yuan; Zhuang, Xin-tian; Li, Ling-xuan

    2011-02-01

    Enterprises are the core power and the carriers to promote the country's economy developing sustainably and rapidly; the listed enterprises are the outstanding companies which can represent the economic level at the places where the enterprises are located, so we establish the cross-shareholding networks of the listed companies between 2002 and 2009, and then analyze the mutual investment at company-level, province-level and region-level. We have researched the overall trend of economic development and the overall tendency of capital flow of China in the recent 8 years based on the cross-shareholding networks, the influence of a global economic crisis on the stock markets and the overall economics of China in 2008 and the recovery of the economy after the economic crisis. Moreover, we analyze the variations of the cross-shareholding networks and the influence of the state-owned large and medium enterprises listing frequently on Chinese stock markets. We divide the provinces of China into 3 main categories according to their industrial situations. Though the analysis, we find that the wealth gap between the different areas is not significantly reduced even though the government has carried out strategies such as the Development of the West Regions and the Rejuvenation of Old Industrial Bases in Northeastern China. We analyze the cumulative distribution function of the degree of the vertices and use large amounts of data to do empirical analysis. The methods used include the hierarchical cluster analysis, regression analysis, etc.

  3. Personnel Profile: Characteristics of Certified Public School Employees 1980-1981 through 1990-1991.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of LEA Personnel Services.

    This report provides information on selected characteristics of certified public school employees between 1980-81 and 1990-91. Information on certified personnel in 1989-90 was not available. Certified employees are grouped into function areas such as teachers, principals, guidance counselors, etc., based on each person's primary work assignment.…

  4. Value-based HR practices, i-deals and clinical error control with CSR as a moderator.

    PubMed

    Luu, Tuan; Rowley, Chris; Siengthai, Sununta; Thanh Thao, Vo

    2017-05-08

    Purpose Notwithstanding the rising magnitude of system factors in patient safety improvement, "human factors" such as idiosyncratic deals (i-deals) which also contribute to the adjustment of system deficiencies should not be neglected. The purpose of this paper is to investigate the role of value-based HR practices in catalyzing i-deals, which then influence clinical error control. The research further examines the moderating role of corporate social responsibility (CSR) on the effect of value-based HR practices on i-deals. Design/methodology/approach The data were collected from middle-level clinicians from hospitals in the Vietnam context. Findings The research results confirmed the effect chain from value-based HR practices through i-deals to clinical error control with CSR as a moderator. Originality/value The HRM literature is expanded through enlisting i-deals and clinical error control as the outcomes of HR practices.

  5. Certified reference materials and reference methods for nuclear safeguards and security.

    PubMed

    Jakopič, R; Sturm, M; Kraiem, M; Richter, S; Aregbe, Y

    2013-11-01

    Confidence in comparability and reliability of measurement results in nuclear material and environmental sample analysis are established via certified reference materials (CRMs), reference measurements, and inter-laboratory comparisons (ILCs). Increased needs for quality control tools in proliferation resistance, environmental sample analysis, development of measurement capabilities over the years and progress in modern analytical techniques are the main reasons for the development of new reference materials and reference methods for nuclear safeguards and security. The Institute for Reference Materials and Measurements (IRMM) prepares and certifices large quantities of the so-called "large-sized dried" (LSD) spikes for accurate measurement of the uranium and plutonium content in dissolved nuclear fuel solutions by isotope dilution mass spectrometry (IDMS) and also develops particle reference materials applied for the detection of nuclear signatures in environmental samples. IRMM is currently replacing some of its exhausted stocks of CRMs with new ones whose specifications are up-to-date and tailored for the demands of modern analytical techniques. Some of the existing materials will be re-measured to improve the uncertainties associated with their certified values, and to enable laboratories to reduce their combined measurement uncertainty. Safeguards involve the quantitative verification by independent measurements so that no nuclear material is diverted from its intended peaceful use. Safeguards authorities pay particular attention to plutonium and the uranium isotope (235)U, indicating the so-called 'enrichment', in nuclear material and in environmental samples. In addition to the verification of the major ratios, n((235)U)/n((238)U) and n((240)Pu)/n((239)Pu), the minor ratios of the less abundant uranium and plutonium isotopes contain valuable information about the origin and the 'history' of material used for commercial or possibly clandestine purposes, and

  6. ENERGY STAR Certified Audio Video

    EPA Pesticide Factsheets

    Certified models meet all ENERGY STAR requirements as listed in the Version 3.0 ENERGY STAR Program Requirements for Audio Video Equipment that are effective as of May 1, 2013. A detailed listing of key efficiency criteria are available at http://www.energystar.gov/index.cfm?c=audio_dvd.pr_crit_audio_dvd

  7. ENERGY STAR Certified Ventilating Fans

    EPA Pesticide Factsheets

    Certified models meet all ENERGY STAR requirements as listed in the Version 4.0 ENERGY STAR Program Requirements for Ventilating Fans that are effective as of October 1, 2015. A detailed listing of key efficiency criteria are available at http://www.energystar.gov/index.cfm?c=vent_fans.pr_crit_vent_fans

  8. ENERGY STAR Certified Ceiling Fans

    EPA Pesticide Factsheets

    Certified models meet all ENERGY STAR requirements as listed in the Version 3.0 ENERGY STAR Program Requirements for Ceiling Fans that are effective as of April 1, 2012. A detailed listing of key efficiency criteria are available at http://www.energystar.gov/index.cfm?c=ceiling_fans.pr_crit_ceiling_fans

  9. An Entrepreneurial Learning Exercise as a Pedagogical Tool for Teaching CSR: A Peruvian Study

    ERIC Educational Resources Information Center

    Farber, Vanina A.; Prialé, María Angela; Fuchs, Rosa María

    2015-01-01

    This paper reports on an exploratory cross-sectional study of the value of an entrepreneurial learning exercise as a tool for examining the entrepreneurship dimension of corporate social responsibility (CSR). The study used grounded theory to analyse diaries kept by graduate (MBA) students during the "20 Nuevos Soles Project". From the…

  10. Follow-Up Study of Rural Schools Implementing CSR Programs in the Southwest. Research Report.

    ERIC Educational Resources Information Center

    Carlson, Robert V.

    Case studies of five small and isolated rural schools in the Southwest focused on their ability to fully implement Comprehensive School Reform Demonstration (CSR) programs over the 3-year period of their federal grants. Data were gathered via interviews with school personnel, classroom observations, document reviews, and telephone interviews with…

  11. 40 CFR 80.1611 - Standards and requirements for certified ethanol denaturant.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... certified ethanol denaturant. 80.1611 Section 80.1611 Protection of Environment ENVIRONMENTAL PROTECTION....1611 Standards and requirements for certified ethanol denaturant. Producers and importers of ethanol denaturant that is suitable for the manufacture of denatured fuel ethanol (DFE) meeting federal quality...

  12. 40 CFR 161.175 - Certified limits.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... how the certified limits were arrived at (e.g., sample analysis, quantitative estimate based on....175 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data Requirements § 161.175...

  13. 20 CFR 416.804 - Certified copy in lieu of original.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Certified copy in lieu of original. 416.804... AGED, BLIND, AND DISABLED Determination of Age § 416.804 Certified copy in lieu of original. In lieu of the original of any record, except a Bible or other family record, there may be submitted as evidence...

  14. Progress towards CSR RL06 GRACE gravity solutions

    NASA Astrophysics Data System (ADS)

    Save, Himanshu

    2017-04-01

    The GRACE project plans to re-processes the GRACE mission data in order to be consistent with the first gravity products released by the GRACE-FO project. The next generation Release-06 (RL06) gravity products from GRACE will include the improvements in GRACE Level-1 data products, background gravity models and the processing methodology. This paper will outline the planned improvements for CSR - RL06 and discuss the preliminary results. This paper will discuss the evolution of the quality of the GRACE solutions, especially over the past few years. We will also discuss the possible challenges we may face in connecting/extending the measurements of mass fluxes from the GRACE era to the GRACE-FO era due quality of the GRACE solutions from recent years.

  15. 13 CFR 124.1003 - How does a firm become certified as an SDB?

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... as an SDB? 124.1003 Section 124.1003 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION 8(a... certified as an SDB? (a) All firms that are current Participants in SBA's 8(a) BD program are automatically deemed to be certified SDBs. (b) Any firm seeking to be certified as an SDB in order to represent that it...

  16. 13 CFR 124.1003 - How does a firm become certified as an SDB?

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... as an SDB? 124.1003 Section 124.1003 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION 8(a... certified as an SDB? (a) All firms that are current Participants in SBA's 8(a) BD program are automatically deemed to be certified SDBs. (b) Any firm seeking to be certified as an SDB in order to represent that it...

  17. 13 CFR 124.1003 - How does a firm become certified as an SDB?

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... as an SDB? 124.1003 Section 124.1003 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION 8(a... certified as an SDB? (a) All firms that are current Participants in SBA's 8(a) BD program are automatically deemed to be certified SDBs. (b) Any firm seeking to be certified as an SDB in order to represent that it...

  18. 13 CFR 124.1003 - How does a firm become certified as an SDB?

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... as an SDB? 124.1003 Section 124.1003 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION 8(a... certified as an SDB? (a) All firms that are current Participants in SBA's 8(a) BD program are automatically deemed to be certified SDBs. (b) Any firm seeking to be certified as an SDB in order to represent that it...

  19. 13 CFR 124.1003 - How does a firm become certified as an SDB?

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... as an SDB? 124.1003 Section 124.1003 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION 8(a... certified as an SDB? (a) All firms that are current Participants in SBA's 8(a) BD program are automatically deemed to be certified SDBs. (b) Any firm seeking to be certified as an SDB in order to represent that it...

  20. The Use of Certified Mail in Mail Surveys. Research Memorandum No. 73-25.

    ERIC Educational Resources Information Center

    Echternacht, Gary J.; McCaffrey, Patty J.

    The cost effectiveness of using certified mail as a device to raise response rates in mail surveys is investigated. Of the three optional services offered by the Post Office when sending certified mail, the base certified rate was recommended, since the Post Office often failed to perform the more expensive services. A sample of 120 students from…

  1. Certified organic vegetable production for market

    USDA-ARS?s Scientific Manuscript database

    Federal guidelines for organic certification in 2002 provided structure for producers and processors to market certified organic foods. The guidelines provide general provisions and processes for obtaining and maintaining organic certification, but did not specify best management practices for crop...

  2. 26 CFR 1.955-1 - Shareholder's pro rata share of amount of previously excluded subpart F income withdrawn from...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    .... Pursuant to section 951(a)(1)(A)(ii) and the regulations thereunder, a United States shareholder of a... countries at the close of the taxable year, minus (ii) The amount (if any) by which recognized losses on...) The sum of the controlled foreign corporation's earnings and profits (or deficit in earnings and...

  3. 26 CFR 1.902-3 - Credit for domestic corporate shareholder of a foreign corporation for foreign income taxes paid...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... the United States. (3) Second-tier corporation. (i) In the case of dividends paid to a first-tier... shareholder ending after that date, the foreign corporation is a “second-tier corporation” if at least 10... corporation by a foreign corporation before January 13, 1971, the foreign corporation is a “second-tier...

  4. Exploring the Rhetorical Use of Interactional Metadiscourse: A Comparison of Letters to Shareholders of American and Chinese Financial Companies

    ERIC Educational Resources Information Center

    Xiaoqin, Liu

    2017-01-01

    By taking Hyland and Tse's (2004) interactional metadiscourse model, this study attempts to compare the incidence of the interactional metadiscourse markers in letters to shareholders of American and Chinese companies in the financial industry and their rhetorical functions. This study makes American corpus of 41 letters and Chinese corpus of 37…

  5. Regulation of Controlled Substance Prescribing: An Overview for Certified Nurse-Midwives and Certified Midwives.

    PubMed

    Osborne, Kathryn

    2017-05-01

    In addition to the regulation of prescriptive authority and prescribing practices conducted by individual states, the prescription of controlled substances is also regulated at the federal level by the US Drug Enforcement Administration (DEA). While there are variations in state laws relative to controlled substance prescribing, federal law is uniform across states as established by the Controlled Substances Act (21 United States Code § 801-890) and the DEA Regulations (Title 21, Code of Federal Regulations). The only controlled substance for which states have authorized use that is outside the regulations set forth in the Controlled Substances Act is marijuana for the treatment of certain medical conditions. A review of statutes and administrative rules for all 50 states and the District of Columbia revealed that certified midwives (CMs) are authorized to prescribe controlled substances only in the state of New York, and there are variations across states in the regulation of controlled substance prescribing by certified nurse-midwives (CNMs). The purpose of this article is to examine the federal regulation of controlled substance prescribing by the US DEA and common variations in state regulations relative to controlled substance prescribing. © 2017 by the American College of Nurse-Midwives.

  6. Regulation of prescriptive authority for certified nurse-midwives and certified midwives: a national overview.

    PubMed

    Osborne, Kathryn

    2011-01-01

    Certified nurse-midwives (CNMs) and certified midwives (CMs) provide primary care to women across the lifespan. Yet these primary care providers face barriers to practice that include restrictive state laws and regulations regarding prescriptive authority. The purpose of this review is to critically examine and report the regulatory requirements relative to prescriptive authority for CNMs/CMs in the United States. State statutes and rules relative to midwifery practice were reviewed for all 50 United States and the District of Columbia. CNMs have been granted the authority to write prescriptions in all 50 United States and the District of Columbia, while CMs have been granted prescriptive authority only in the state of New York. Prescriptive authority for CNMs and CMs is regulated by individual state agencies and regulatory boards. Regulations regarding prescriptive authority for CNMs and CMs vary widely from state to state and are described, with a summary for each state presented. While CNMs are granted fully independent prescriptive authority in some states, the regulatory requirements relative to prescriptive authority for CNMs/CMs limit patients' access to necessary services in most states. © 2011 by the American College of Nurse-Midwives.

  7. 24 CFR 3286.411 - Certifying installation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... manufactured home has been installed in accordance with: (i) An installation design and instructions that have... URBAN DEVELOPMENT MANUFACTURED HOME INSTALLATION PROGRAM Installer Responsibilities of Installation in...; or (ii) An installation design and instructions that have been prepared and certified by a...

  8. 40 CFR 161.175 - Certified limits.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 25 2013-07-01 2013-07-01 false Certified limits. 161.175 Section 161.175 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data Requirements § 161.175...

  9. 40 CFR 161.175 - Certified limits.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Certified limits. 161.175 Section 161.175 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS DATA REQUIREMENTS FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data Requirements § 161.175...

  10. 40 CFR 80.1644 - Sampling and testing requirements for producers and importers of certified ethanol denaturant.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... producers and importers of certified ethanol denaturant. 80.1644 Section 80.1644 Protection of Environment... ethanol denaturant. (a) Sample and test each batch of certified ethanol denaturant. (1) Producers and importers of certified ethanol denaturant shall collect a representative sample from each batch of certified...

  11. 26 CFR 1.955A-1 - Shareholder's pro rata share of amount of previously excluded subpart F income withdrawn from...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... section 951(a)(1)(A)(iii) and the regulations thereunder, a United States shareholder of such controlled... (ii) The amount (if any) by which recognized losses on sales or exchanges by such corporation during... sum of (1) the controlled foreign corporation's earnings and profits (or deficit in earnings and...

  12. Sustainable Eco Coastal Development Through Corporate Social Responsibility (CSR) Program

    NASA Astrophysics Data System (ADS)

    Rakhmanissazly, Arsi; Mursito Ardy, Yong; Abdullah

    2017-02-01

    Besides technical problems the company’s operational constraints that may effect high deficiency for the company is the company - community conflicts. Company - community conflict can also arise depends on the geographic conditions and characteristics of the community itself. Some studies has show that coastal community have higher level of social risk when compared to non-coastal community. Also, the coastal community ussually only rely on what sea provides as their main livelihood. Because of the level of education still contemtible the community couldn’t optimized the potential of their own area. Corporate Social Responsibility (CSR) har emerged as an important approach for addressing the social and environmental impact of company activities. Through CSR program, PT Pertamina EP Asset 3 Tambun Field (PEP) try to form value integration by utilizing resources from the community and the company by making sustainable eco - coastal living in Desa Tambaksari, Karawang, one of PEP working area. Using sustainable livelihood approach begin with compiling data by doing social mapping PEP has initiate the area to becoming Fish Processing Industry Centre. By implementing PDCA in every steps of the program, PEP has multiplied some other programs such as Organic Fish Feed Processing, Seaweed Farming and Waste Bank for Green Coastal Village. These program is PEP’s effort to create a sustainability environment by enhancing the community’s potentials as well as resolving social problems around Tambaksari. The most important result besides getting our license to operate from the community, is the community itself can grow into an eco coastal sustainable system.

  13. 41 CFR 101-42.1102-6 - Noncertified and certified electronic products.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... certified electronic products. 101-42.1102-6 Section 101-42.1102-6 Public Contracts and Property Management... certified electronic products. (a) Utilization requirements.(1) Excess electronic items for which radiation... shall identify noncertified electronic products and shall contain a statement that the items may not be...

  14. 41 CFR 101-42.1102-6 - Noncertified and certified electronic products.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... certified electronic products. 101-42.1102-6 Section 101-42.1102-6 Public Contracts and Property Management... certified electronic products. (a) Utilization requirements.(1) Excess electronic items for which radiation... shall identify noncertified electronic products and shall contain a statement that the items may not be...

  15. 41 CFR 101-42.1102-6 - Noncertified and certified electronic products.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... certified electronic products. 101-42.1102-6 Section 101-42.1102-6 Public Contracts and Property Management... certified electronic products. (a) Utilization requirements.(1) Excess electronic items for which radiation... shall identify noncertified electronic products and shall contain a statement that the items may not be...

  16. 41 CFR 101-42.1102-6 - Noncertified and certified electronic products.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... certified electronic products. 101-42.1102-6 Section 101-42.1102-6 Public Contracts and Property Management... certified electronic products. (a) Utilization requirements.(1) Excess electronic items for which radiation... shall identify noncertified electronic products and shall contain a statement that the items may not be...

  17. 9 CFR 355.29 - Composition of certified products for dogs, cats, and other carnivora.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... dogs, cats, and other carnivora. 355.29 Section 355.29 Animals and Animal Products FOOD SAFETY AND... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER... Composition of Certified Products § 355.29 Composition of certified products for dogs, cats, and other...

  18. 9 CFR 355.29 - Composition of certified products for dogs, cats, and other carnivora.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... dogs, cats, and other carnivora. 355.29 Section 355.29 Animals and Animal Products FOOD SAFETY AND... PRODUCTS INSPECTION AND VOLUNTARY INSPECTION AND CERTIFICATION CERTIFIED PRODUCTS FOR DOGS, CATS, AND OTHER... Composition of Certified Products § 355.29 Composition of certified products for dogs, cats, and other...

  19. 9 CFR 355.29 - Composition of certified products for dogs, cats, and other carnivora.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... for human food purposes; (iii) Certified animal protein supplement may contain not more than 3 percent... protein supplement shall contain not less than 3 percent fat. (2) Certified pet food supplement shall... carnivora. (a) Composition of canned or semi-moist certified maintenance food. (1) Only ingredients which...

  20. 9 CFR 355.29 - Composition of certified products for dogs, cats, and other carnivora.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... for human food purposes; (iii) Certified animal protein supplement may contain not more than 3 percent... protein supplement shall contain not less than 3 percent fat. (2) Certified pet food supplement shall... carnivora. (a) Composition of canned or semi-moist certified maintenance food. (1) Only ingredients which...

  1. 9 CFR 355.29 - Composition of certified products for dogs, cats, and other carnivora.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... for human food purposes; (iii) Certified animal protein supplement may contain not more than 3 percent... protein supplement shall contain not less than 3 percent fat. (2) Certified pet food supplement shall... carnivora. (a) Composition of canned or semi-moist certified maintenance food. (1) Only ingredients which...

  2. Medicaid estate planning: practices and perceptions of Medicaid workers, elder law attorneys, and certified financial planners.

    PubMed

    Walker, L; Gruman, C; Robison, J

    1998-08-01

    This study examined Medicaid estate planning (MEP) through the experiences and perceptions of three groups in Connecticut: Medicaid eligibility workers (n = 128), elder law attorneys (n = 41), and certified financial planners (n = 29). Respondent groups varied significantly with regard to their perceptions of prevalence and magnitude of MEP, the nature of transferred assets, mechanisms for transfers, and characteristics of the "typical" client participating in asset divestiture for the purpose of qualifying for Medicaid. This substantial lack of concordance among those professionals most closely involved with MEP poses challenges for policy and research in this area.

  3. Integrating Districts in Comprehensive School Reform in the Middle-Grades: Lessons from Middle Start CSR

    ERIC Educational Resources Information Center

    Gopalan, Pritha

    2004-01-01

    This report compares district leaders' perspectives on changes in school capacity, student outcomes and district policy over three years of implementation of Middle Start (MS), a comprehensive school reform program to demonstrate the potential for improving the effectiveness and sustainability of CSR at the school level through integrating…

  4. 48 CFR 52.215-12 - Subcontractor Certified Cost or Pricing Data.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Cost or Pricing Data. 52.215-12 Section 52.215-12 Federal Acquisition Regulations System FEDERAL... Provisions and Clauses 52.215-12 Subcontractor Certified Cost or Pricing Data. As prescribed in 15.408(d), insert the following clause: Subcontractor Certified Cost or Pricing Data (OCT 2010) (a) Before awarding...

  5. 49 CFR 567.7 - Requirements for persons who alter certified vehicles.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 49 Transportation 6 2013-10-01 2013-10-01 false Requirements for persons who alter certified vehicles. 567.7 Section 567.7 Transportation Other Regulations Relating to Transportation (Continued) NATIONAL HIGHWAY TRAFFIC SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CERTIFICATION § 567.7 Requirements for persons who alter certified vehicles...

  6. 31 CFR 357.31 - Certifying individuals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Certifying individuals. 357.31 Section 357.31 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... institutions, corporate central credit unions, and institutions that are members of Treasury-recognized...

  7. 31 CFR 306.45 - Certifying individuals.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... employees of depository institutions, corporate central credit unions, and institutions that are members of... certifying individual's presence after he or she has established the identity of the person seeking the... prescribed in procedures established by the Department. (4) Officers and employees of corporate central...

  8. 31 CFR 306.45 - Certifying individuals.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... employees of depository institutions, corporate central credit unions, and institutions that are members of... certifying individual's presence after he or she has established the identity of the person seeking the... prescribed in procedures established by the Department. (4) Officers and employees of corporate central...

  9. 31 CFR 306.45 - Certifying individuals.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... employees of depository institutions, corporate central credit unions, and institutions that are members of... certifying individual's presence after he or she has established the identity of the person seeking the... prescribed in procedures established by the Department. (4) Officers and employees of corporate central...

  10. 31 CFR 306.45 - Certifying individuals.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... employees of depository institutions, corporate central credit unions, and institutions that are members of... certifying individual's presence after he or she has established the identity of the person seeking the... prescribed in procedures established by the Department. (4) Officers and employees of corporate central...

  11. Teacher Quality: A Comparison of National Board--Certified and Non--Board--Certified Teachers of Deaf Students

    ERIC Educational Resources Information Center

    Scheetz, Nanci A.; Martin, David S.

    2006-01-01

    The study was designed to identify specific components of teacher excellence, focusing initially on the characteristics of the small number of teachers of the deaf who are certified by the National Board for Professional Teaching Standards (NBPTS), then comparing those with the characteristics of other teachers identified as master teachers by…

  12. 40 CFR 60.1195 - What if all the certified operators must be temporarily offsite?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... corrective action summary to the Administrator every 4 weeks following the initial notification. If the... facility operator and certified shift supervisor are offsite for more than 12 hours, but for 2 weeks or... facility operator and certified shift supervisor are offsite for more than 2 weeks, and no other certified...

  13. 40 CFR 62.15140 - What if all the certified operators must be temporarily offsite?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... more than 12 hours, but for 2 weeks or less, and no other certified operator is onsite, the... more than 2 weeks and no other certified operator is onsite, the provisionally certified control room... supervisor is onsite. (2) Submit a status report and corrective action summary to the Administrator every 4...

  14. 40 CFR 62.15140 - What if all the certified operators must be temporarily offsite?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... more than 12 hours, but for 2 weeks or less, and no other certified operator is onsite, the... more than 2 weeks and no other certified operator is onsite, the provisionally certified control room... supervisor is onsite. (2) Submit a status report and corrective action summary to the Administrator every 4...

  15. 40 CFR 1054.690 - What bond requirements apply for certified engines?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Before introducing certified engines into U.S. commerce, you must post a bond to cover any potential... importing engines that have been certified by someone else. Note that you might also post bond under this... test conducted by EPA officials or having been found by EPA to be noncompliant under applicable...

  16. 40 CFR 1054.690 - What bond requirements apply for certified engines?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Before introducing certified engines into U.S. commerce, you must post a bond to cover any potential... importing engines that have been certified by someone else. Note that you might also post bond under this... test conducted by EPA officials or having been found by EPA to be noncompliant under applicable...

  17. 40 CFR 1054.690 - What bond requirements apply for certified engines?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Before introducing certified engines into U.S. commerce, you must post a bond to cover any potential... importing engines that have been certified by someone else. Note that you might also post bond under this... test conducted by EPA officials or having been found by EPA to be noncompliant under applicable...

  18. 40 CFR 1054.690 - What bond requirements apply for certified engines?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Before introducing certified engines into U.S. commerce, you must post a bond to cover any potential... importing engines that have been certified by someone else. Note that you might also post bond under this... test conducted by EPA officials or having been found by EPA to be noncompliant under applicable...

  19. 40 CFR 1054.690 - What bond requirements apply for certified engines?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Before introducing certified engines into U.S. commerce, you must post a bond to cover any potential... importing engines that have been certified by someone else. Note that you might also post bond under this... test conducted by EPA officials or having been found by EPA to be noncompliant under applicable...

  20. 31 CFR 357.31 - Certifying individuals.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... SERVICE, DEPARTMENT OF THE TREASURY BUREAU OF THE PUBLIC DEBT REGULATIONS GOVERNING BOOK-ENTRY TREASURY... DIRECT Legacy Treasury Direct Book-Entry Securities System (Legacy Treasury Direct) § 357.31 Certifying... has placed an endorsement on the form reading substantially as follows: “Absence of signature by owner...

  1. 31 CFR 306.45 - Certifying individuals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Certifying individuals. 306.45 Section 306.45 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... employees of depository institutions, corporate central credit unions, and institutions that are members of...

  2. The drift chamber array at the external target facility in HIRFL-CSR

    NASA Astrophysics Data System (ADS)

    Sun, Y. Z.; Sun, Z. Y.; Wang, S. T.; Duan, L. M.; Sun, Y.; Yan, D.; Tang, S. W.; Yang, H. R.; Lu, C. G.; Ma, P.; Yu, Y. H.; Zhang, X. H.; Yue, K.; Fang, F.; Su, H.

    2018-06-01

    A drift chamber array at the External Target Facility in HIRFL-CSR has been constructed for three-dimensional particle tracking in high-energy radioactive ion beam experiments. The design, readout, track reconstruction program and calibration procedures for the detector are described. The drift chamber array was tested in a 311 AMeV 40Ar beam experiment. The detector performance based on the measurements of the beam test is presented. A spatial resolution of 230 μm is achieved.

  3. Job Analysis of the Professional Requirements of the Certified Financial Planner.

    ERIC Educational Resources Information Center

    Skurnik, Larry

    A study examined the job functions of certified financial planners, the areas of knowledge needed by new financial planners, the links between these knowledge areas and the job functions of financial planners, and the validity of the examinations currently used by the College of Financial Planning to certify financial planners. A multimethod…

  4. Environmental impact of non-certified versus certified (ASC) intensive Pangasius aquaculture in Vietnam, a comparison based on a statistically supported LCA.

    PubMed

    Nhu, Trang T; Schaubroeck, Thomas; Henriksson, Patrik J G; Bosma, Roel; Sorgeloos, Patrick; Dewulf, Jo

    2016-12-01

    Pangasius production in Vietnam is widely known as a success story in aquaculture, the fastest growing global food system because of its tremendous expansion by volume, value and the number of international markets to which Pangasius has been exported in recent years. While certification schemes are becoming significant features of international fish trade and marketing, an increasing number of Pangasius producers have followed at least one of the certification schemes recognised by international markets to incorporate environmental and social sustainability practices in aquaculture, typically the Pangasius Aquaculture Dialogue (PAD) scheme certified by the Aquaculture Stewardship Council (ASC). An assessment of the environmental benefit of applying certification schemes on Pangasius production, however, is still needed. This article compared the environmental impact of ASC-certified versus non-ASC certified intensive Pangasius aquaculture, using a statistically supported LCA. We focused on both resource-related (water, land and total resources) and emissions-related (global warming, acidification, freshwater and marine eutrophication) categories. The ASC certification scheme was shown to be a good approach for determining adequate environmental sustainability, especially concerning emissions-related categories, in Pangasius production. However, the non-ASC certified farms, due to the large spread, the impact (e.g., water resources and freshwater eutrophication) was possibly lower for a certain farm. However, this result was not generally prominent. Further improvements in intensive Pangasius production to inspire certification schemes are proposed, e.g., making the implementation of certification schemes more affordable, well-oriented and facilitated; reducing consumed feed amounts and of the incorporated share in fishmeal, especially domestic fishmeal, etc. However, their implementation should be vetted with key stakeholders to assess their feasibility. Copyright

  5. The phase slip factor of the electrostatic cryogenic storage ring CSR

    NASA Astrophysics Data System (ADS)

    Grieser, Manfred; von Hahn, Robert; Vogel, Stephen; Wolf, Andreas

    2017-07-01

    To determine the momentum spread of an ion beam from the measured revolution frequency distribution, the knowledge of the phase slip factor of the storage ring is necessary. The slip factor was measured for various working points of the cryogenic storage ring CSR at MPI for Nuclear Physics, Heidelberg and was compared with simulations. The predicted functional relationship of the slip factor and the horizontal tune depends on the different islands of stability, which has been experimentally verified. This behavior of the slip factor is in clear contrast to that of magnetic storage rings.

  6. 49 CFR 240.129 - Criteria for monitoring operational performance of certified engineers.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... certified engineers. 240.129 Section 240.129 Transportation Other Regulations Relating to Transportation... LOCOMOTIVE ENGINEERS Component Elements of the Certification Process § 240.129 Criteria for monitoring operational performance of certified engineers. (a) Each railroad's program shall include criteria and...

  7. 49 CFR 240.129 - Criteria for monitoring operational performance of certified engineers.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... certified engineers. 240.129 Section 240.129 Transportation Other Regulations Relating to Transportation... LOCOMOTIVE ENGINEERS Component Elements of the Certification Process § 240.129 Criteria for monitoring operational performance of certified engineers. (a) Each railroad's program shall include criteria and...

  8. 49 CFR 240.129 - Criteria for monitoring operational performance of certified engineers.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... certified engineers. 240.129 Section 240.129 Transportation Other Regulations Relating to Transportation... LOCOMOTIVE ENGINEERS Component Elements of the Certification Process § 240.129 Criteria for monitoring operational performance of certified engineers. (a) Each railroad's program shall include criteria and...

  9. 31 CFR 346.14 - Certifying officers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Certifying officers. 346.14 Section 346.14 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... imprint of the corporate seal, or, where the institution is an authorized issuing agent for United States...

  10. 31 CFR 341.14 - Certifying officers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 31 Money and Finance: Treasury 2 2010-07-01 2010-07-01 false Certifying officers. 341.14 Section 341.14 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) FISCAL... imprint of the corporate seal, or, where the institution is an authorized issuing agent for United States...

  11. 30 CFR 75.100 - Certified person.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Certified person. 75.100 Section 75.100 Mineral Resources MINE SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR COAL MINE SAFETY AND HEALTH MANDATORY... and Qualification Center, P.O. Box 25367, Denver Federal Center, Denver, Colorado 80225. (2) A person...

  12. Assessment of long-term impact of formal certified cardiopulmonary resuscitation training program among nurses.

    PubMed

    Saramma, P P; Raj, L Suja; Dash, P K; Sarma, P S

    2016-04-01

    Cardiopulmonary resuscitation (CPR) and emergency cardiovascular care guidelines are periodically renewed and published by the American Heart Association. Formal training programs are conducted based on these guidelines. Despite widespread training CPR is often poorly performed. Hospital educators spend a significant amount of time and money in training health professionals and maintaining basic life support (BLS) and advanced cardiac life support (ACLS) skills among them. However, very little data are available in the literature highlighting the long-term impact of these training. To evaluate the impact of formal certified CPR training program on the knowledge and skill of CPR among nurses, to identify self-reported outcomes of attempted CPR and training needs of nurses. Tertiary care hospital, Prospective, repeated-measures design. A series of certified BLS and ACLS training programs were conducted during 2010 and 2011. Written and practical performance tests were done. Final testing was undertaken 3-4 years after training. The sample included all available, willing CPR certified nurses and experience matched CPR noncertified nurses. SPSS for Windows version 21.0. The majority of the 206 nurses (93 CPR certified and 113 noncertified) were females. There was a statistically significant increase in mean knowledge level and overall performance before and after the formal certified CPR training program (P = 0.000). However, the mean knowledge scores were equivalent among the CPR certified and noncertified nurses, although the certified nurses scored a higher mean score (P = 0.140). Formal certified CPR training program increases CPR knowledge and skill. However, significant long-term effects could not be found. There is a need for regular and periodic recertification.

  13. 48 CFR 52.215-13 - Subcontractor Certified Cost or Pricing Data-Modifications.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Cost or Pricing Data-Modifications. 52.215-13 Section 52.215-13 Federal Acquisition Regulations System... Text of Provisions and Clauses 52.215-13 Subcontractor Certified Cost or Pricing Data—Modifications. As prescribed in 15.408(e), insert the following clause: Subcontractor Certified Cost or Pricing Data...

  14. Effect of Certified Personal Trainer Services on Stage of Exercise Behavior and Exercise Mediators in Female College Students

    ERIC Educational Resources Information Center

    Fischer, Donald V.; Bryant, Jennifer

    2008-01-01

    Objective: The authors examined the effect of certified personal trainer services on exercise behavior by using the transtheoretical model of behavioral change. Participants: Female college students (n = 449) completed surveys during the first week (T1) and last week (T2) of the fall semester. Methods: Students receiving personal trainer services…

  15. Network of listed companies based on common shareholders and the prediction of market volatility

    NASA Astrophysics Data System (ADS)

    Li, Jie; Ren, Da; Feng, Xu; Zhang, Yongjie

    2016-11-01

    In this paper, we build a network of listed companies in the Chinese stock market based on common shareholding data from 2003 to 2013. We analyze the evolution of topological characteristics of the network (e.g., average degree, diameter, average path length and clustering coefficient) with respect to the time sequence. Additionally, we consider the economic implications of topological characteristic changes on market volatility and use them to make future predictions. Our study finds that the network diameter significantly predicts volatility. After adding control variables used in traditional financial studies (volume, turnover and previous volatility), network topology still significantly influences volatility and improves the predictive ability of the model.

  16. 30 CFR 884.17 - Other uses by certified States and Indian tribes.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... tribes. 884.17 Section 884.17 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT... certified States and Indian tribes. (a) The State reclamation plan may provide for construction of specific... applications for uses other than coal reclamation by certified States and Indian tribes may be submitted in...

  17. 30 CFR 884.17 - Other uses by certified States and Indian tribes.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... tribes. 884.17 Section 884.17 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT... certified States and Indian tribes. (a) The State reclamation plan may provide for construction of specific... applications for uses other than coal reclamation by certified States and Indian tribes may be submitted in...

  18. A Study of How Certified and Noncertified Automotive Curriculum Impact Student Achievement

    ERIC Educational Resources Information Center

    VanDalsem, B.

    2010-01-01

    The purpose of this case study was to examine whether written curriculum for Automotive Service Excellence (ASE) certified and non-certified training programs better prepares students for entry-level positions. The theoretical framework based on research by Frase described methodologies for comparing curricula at the system, school, and classroom…

  19. A Comparison of Student Academic Achievement between Alternatively and Traditionally Certified Teachers

    ERIC Educational Resources Information Center

    Stephens, Mary W.

    2007-01-01

    This research study evaluated the achievement of students who were taught by traditionally certified teachers with students who were taught by alternatively certified teachers or those seeking certification through an alternative certification program. The primary purpose of the study was to examine significant differences, if any, in student…

  20. ENERGY STAR Certified Geothermal Heat Pumps

    EPA Pesticide Factsheets

    Certified models meet all ENERGY STAR requirements as listed in the Version 3.0 ENERGY STAR Program Requirements for Geothermal Heat Pumps that are effective as of January 1, 2012. A detailed listing of key efficiency criteria are available at http://www.energystar.gov/index.cfm?c=geo_heat.pr_crit_geo_heat_pumps

  1. 42 CFR 410.69 - Services of a certified registered nurse anesthetist or an anesthesiologist's assistant: Basic...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... certified registered nurse anesthetist or an anesthesiologist's assistant: Basic rule and definitions. (a... registered nurse anesthetist or an anesthesiologist's assistant who is legally authorized to perform the... an anesthesiologist's assistant and a certified registered nurse anesthetist. Certified registered...

  2. Characteristics of official and experimental GRACE time series by GFZ and CSR - with applications to polar signals

    NASA Astrophysics Data System (ADS)

    Horvath, Alexander; Horwath, Martin; Pail, Roland

    2014-05-01

    The Release-05 monthly solutions by the three centers of the GRACE Science and Data System are a significant improvement with respect to the previous Release 4. Meanwhile, previous assessments have revealed different noise levels between the solutions by CSR, GFZ and JPL, and also different amplitudes of interannual signal in the solutions by GFZ as compared to the two other centers. Encouraged by the science community, GFZ and CSR have kindly provided additional sets of time series. GFZ has reprocessed the RL05 monthly solutions (up to degree and order 90) with revised processing. CSR has made available monthly solutions with standard processing up to degree and order 96, in addition to their solutions up to degree and order 60. We compare these different time series with respect to their signal and noise content and analyze them on global and regional scale. For the regional scale our special interest is paid on Antarctica and on revealing polar signals such as ice mass trends and GIA. Following the necessity of destriping, an optimal choice for the setup of the Swenson & Wahr filter approach is evaluated to adapt to the specific signal and noise level in Antarctica. Furthermore we analyze the potential benefit of mixed time series solutions in order to combine the strengths of the solutions available. Concerning the question for an optimal maximum degree we suggest that for resolving large polar ice mass changes, it would be beneficial to provide gravity field variations even beyond degree 90.

  3. Reflections on International Certified Nursing Assistants.

    PubMed

    Shaw, Penelope Ann

    2017-01-01

    The author, a former university faculty member who taught English to speakers of other languages and now a nursing home resident, shares her observations about how English language proficiency, culture, and religious differences affect her care. She provides examples of communication challenges that can be annoying or cause harm, her coping strategies, and reasons many certified nursing assistants might never be fully fluent in English. She explains how international certified nursing assistants can benefit residents because of skills developed by family-centered care in their countries of origin. She also discusses related issues-the importance of being culturally competent about U.S. culture. She points out how religiousness not only affects residents but is a buffer for staff against the stress of physically and emotionally demanding low-wage work. Overall, the author likes receiving care from individuals from other countries, finding reward in comparing how her personal struggle with illness and paralysis resonates with the trauma of migration and how learning firsthand about varying beliefs and attitudes clarifies her identity and place in world history.

  4. Assessment of long-term impact of formal certified cardiopulmonary resuscitation training program among nurses

    PubMed Central

    Saramma, P. P.; Raj, L. Suja; Dash, P. K.; Sarma, P. S.

    2016-01-01

    Context: Cardiopulmonary resuscitation (CPR) and emergency cardiovascular care guidelines are periodically renewed and published by the American Heart Association. Formal training programs are conducted based on these guidelines. Despite widespread training CPR is often poorly performed. Hospital educators spend a significant amount of time and money in training health professionals and maintaining basic life support (BLS) and advanced cardiac life support (ACLS) skills among them. However, very little data are available in the literature highlighting the long-term impact of these training. Aims: To evaluate the impact of formal certified CPR training program on the knowledge and skill of CPR among nurses, to identify self-reported outcomes of attempted CPR and training needs of nurses. Setting and Design: Tertiary care hospital, Prospective, repeated-measures design. Subjects and Methods: A series of certified BLS and ACLS training programs were conducted during 2010 and 2011. Written and practical performance tests were done. Final testing was undertaken 3–4 years after training. The sample included all available, willing CPR certified nurses and experience matched CPR noncertified nurses. Statistical Analysis Used: SPSS for Windows version 21.0. Results: The majority of the 206 nurses (93 CPR certified and 113 noncertified) were females. There was a statistically significant increase in mean knowledge level and overall performance before and after the formal certified CPR training program (P = 0.000). However, the mean knowledge scores were equivalent among the CPR certified and noncertified nurses, although the certified nurses scored a higher mean score (P = 0.140). Conclusions: Formal certified CPR training program increases CPR knowledge and skill. However, significant long-term effects could not be found. There is a need for regular and periodic recertification. PMID:27303137

  5. 42 CFR 410.69 - Services of a certified registered nurse anesthetist or an anesthesiologist's assistant: Basic...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... certified registered nurse anesthetist or an anesthesiologist's assistant: Basic rule and definitions. (a... registered nurse anesthetist or an anesthesiologist's assistant who is legally authorized to perform the... assistant and a certified registered nurse anesthetist. Certified registered nurse anesthetist means a...

  6. 42 CFR 410.69 - Services of a certified registered nurse anesthetist or an anesthesiologist's assistant: Basic...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... certified registered nurse anesthetist or an anesthesiologist's assistant: Basic rule and definitions. (a... registered nurse anesthetist or an anesthesiologist's assistant who is legally authorized to perform the... assistant and a certified registered nurse anesthetist. Certified registered nurse anesthetist means a...

  7. A Preliminary Investigation of Why Few Special Educators Are Nationally Board Certified

    ERIC Educational Resources Information Center

    Benson, Teddi L.; Agran, Martin; Yocom, Dorothy Jean

    2010-01-01

    In 2006, special education teachers made up 12% of the educational workforce but only 7% of National Board Certified teachers. In contrast, general education teachers made up 88% of the educational workforce and 93% of National Board Certified teachers. This study surveyed a sample of special education teachers who successfully completed…

  8. 40 CFR 85.1412 - Maintenance and submittal of records for equipment certifiers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... original equipment being replaced; (4) A description of the quality control plan used to monitor production... taken in implementing the quality control plan, and any subsequent analyses of that data; and (6) All in... the equipment certifier has offered to sell its certified equipment for less than the life cycle cost...

  9. 40 CFR 85.1412 - Maintenance and submittal of records for equipment certifiers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... original equipment being replaced; (4) A description of the quality control plan used to monitor production... taken in implementing the quality control plan, and any subsequent analyses of that data; and (6) All in... the equipment certifier has offered to sell its certified equipment for less than the life cycle cost...

  10. Why Do National Board Certified Teachers from Generation X Leave the Classroom?

    ERIC Educational Resources Information Center

    Crain, Julie Christi

    2013-01-01

    This qualitative multiple case study focused on National Board Certified teachers from Generation X who have left the classroom. The study explored aspects of the teaching profession, the National Board Certification process, and Generation X as potential influences for National Board Certified teachers from Generation X to leave the classroom.…

  11. 76 FR 15049 - Proposed Information Collection (Designation of Certifying Official(s)); Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-18

    ... (Designation of Certifying Official(s)); Comment Request AGENCY: Veterans Benefits Administration, Department of Veterans Affairs. ACTION: Notice. SUMMARY: The Veterans Benefits Administration (VBA), Department... individuals authorized to certify reports on behalf of an educational institution or job training...

  12. Alternative Fuels Data Center: Status Update: E25 Dispensers Certified, E15

    Science.gov Websites

    Alternative Fuels Data Center: Status Update: E25 Dispensers Certified, E15 Warranty Upgraded, and Testing on Ethanol Blends Continues (May 2010) on Facebook Tweet about Alternative Fuels Data Center: Status Update Twitter Bookmark Alternative Fuels Data Center: Status Update: E25 Dispensers Certified, E15 Warranty

  13. 40 CFR 85.1412 - Maintenance and submittal of records for equipment certifiers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... the equipment certifier has offered to sell its certified equipment for less than the life cycle cost... during testing of the equipment and subsequent analyses based on that data, including the mileage and the... taken in implementing the quality control plan, and any subsequent analyses of that data; and (6) All in...

  14. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE..., Netherlands, New Zealand, Norway, People's Republic of China, Philippines, Portugal, Republic of South Africa... Customs purposes in connection with merchandise exported on such date. (2) Certified daily rate. If the...

  15. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE..., Netherlands, New Zealand, Norway, People's Republic of China, Philippines, Portugal, Republic of South Africa... Customs purposes in connection with merchandise exported on such date. (2) Certified daily rate. If the...

  16. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE..., Netherlands, New Zealand, Norway, People's Republic of China, Philippines, Portugal, Republic of South Africa... Customs purposes in connection with merchandise exported on such date. (2) Certified daily rate. If the...

  17. 19 CFR 159.34 - Certified quarterly rate.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE..., Netherlands, New Zealand, Norway, People's Republic of China, Philippines, Portugal, Republic of South Africa... Customs purposes in connection with merchandise exported on such date. (2) Certified daily rate. If the...

  18. 19 CFR 115.6 - Designated Certifying Authorities.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS... containers and road vehicles. The Commissioner has designated the following Certifying Authorities for containers and road vehicles as defined in this part: (1) The American Bureau of Shipping, ABS Plaza, 16855...

  19. 19 CFR 115.6 - Designated Certifying Authorities.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS... containers and road vehicles. The Commissioner has designated the following Certifying Authorities for containers and road vehicles as defined in this part: (1) The American Bureau of Shipping, ABS Plaza, 16855...

  20. 19 CFR 115.6 - Designated Certifying Authorities.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS... containers and road vehicles. The Commissioner has designated the following Certifying Authorities for containers and road vehicles as defined in this part: (1) The American Bureau of Shipping, ABS Plaza, 16855...

  1. 19 CFR 115.6 - Designated Certifying Authorities.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS... containers and road vehicles. The Commissioner has designated the following Certifying Authorities for containers and road vehicles as defined in this part: (1) The American Bureau of Shipping, ABS Plaza, 16855...

  2. 19 CFR 115.6 - Designated Certifying Authorities.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... OF THE TREASURY CARGO CONTAINER AND ROAD VEHICLE CERTIFICATION PURSUANT TO INTERNATIONAL CUSTOMS... containers and road vehicles. The Commissioner has designated the following Certifying Authorities for containers and road vehicles as defined in this part: (1) The American Bureau of Shipping, ABS Plaza, 16855...

  3. NBL CRM 112-A: A new certified isotopic composition

    NASA Astrophysics Data System (ADS)

    Thomas, R. B.; Essex, R. M.; Mason, P.

    2007-12-01

    NBL CRM 112-A Uranium Metal Assay Standard is commonly used as a natural uranium isotopic reference material within the earth science mass spectrometry community. The metal is from the same parent material as NBS SRM 960, the uranyl nitrate solution, CRM 145, and the high-purity uranyl nitrate solution CRM 145-B. Because CRM 112-A has not yet been certified for isotopic composition, it has been assumed that this material has a natural 235U/238U (0.0072527), and the δ234U has been determined by measurement (e.g. -37.1‰; Cheng et al., 2000). These values have been widely used to calibrate the concentration of spikes and standards, and to correct measurements for instrument or mass bias. New, preliminary, isotopic measurements on CRM 145 and CRM 112-A performed at New Brunswick Laboratory suggest that these reference materials have a slightly lower 235U/238U and δ234U than have been commonly used. If this is the case, then data using the accepted values may be slightly biased. The significance of this bias will depend on the uncertainty of the measurement, how the CRM 112-A data is used to correct measurement data, the cited values that were used to correct the data, and the final certified values of the CRM. This fall, New Brunswick Laboratory is certifying the isotopic composition of the CRM 112-A metal using high precision thermal ionization mass spectrometry techniques. Upon completion of certification, the new CRM 112- A standard with certified isotopic ratios will provide the earth science community with a well characterized and traceable reference for calibrating and correcting their mass spectrometry measurement systems.

  4. 19 CFR 10.57 - Certified seed potatoes, and seed corn or maize.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Certified seed potatoes, and seed corn or maize... Provisions Potatoes, Corn, Or Maize § 10.57 Certified seed potatoes, and seed corn or maize. Claim for classification as seed potatoes under subheading 0701.10.00, as seed corn (maize) under subheading 1005.10...

  5. 19 CFR 10.57 - Certified seed potatoes, and seed corn or maize.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Certified seed potatoes, and seed corn or maize... Provisions Potatoes, Corn, Or Maize § 10.57 Certified seed potatoes, and seed corn or maize. Claim for classification as seed potatoes under subheading 0701.10.00, as seed corn (maize) under subheading 1005.10...

  6. 19 CFR 10.57 - Certified seed potatoes, and seed corn or maize.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 19 Customs Duties 1 2014-04-01 2014-04-01 false Certified seed potatoes, and seed corn or maize... Provisions Potatoes, Corn, Or Maize § 10.57 Certified seed potatoes, and seed corn or maize. Claim for classification as seed potatoes under subheading 0701.10.00, as seed corn (maize) under subheading 1005.10...

  7. 19 CFR 10.57 - Certified seed potatoes, and seed corn or maize.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 19 Customs Duties 1 2013-04-01 2013-04-01 false Certified seed potatoes, and seed corn or maize... Provisions Potatoes, Corn, Or Maize § 10.57 Certified seed potatoes, and seed corn or maize. Claim for classification as seed potatoes under subheading 0701.10.00, as seed corn (maize) under subheading 1005.10...

  8. 19 CFR 10.57 - Certified seed potatoes, and seed corn or maize.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 19 Customs Duties 1 2012-04-01 2012-04-01 false Certified seed potatoes, and seed corn or maize... Provisions Potatoes, Corn, Or Maize § 10.57 Certified seed potatoes, and seed corn or maize. Claim for classification as seed potatoes under subheading 0701.10.00, as seed corn (maize) under subheading 1005.10...

  9. Preventing School Dropout and Ensuring Success for English Language Learners and Native American Students. CSR Connection.

    ERIC Educational Resources Information Center

    Housman, Naomi G.; Martinez, Monica R.

    This Spring 2002 issue of the occasional paper, CSR Connection, reports on information that builds the capacity of schools to raise the academic achievement of all students. The success of English language learners and Native American students in U.S. public schools has been, and continues to be, impeded by deep "disconnects" between schools and…

  10. Comparision of alternatively certified and traditionally certified Missouri high school science teachers' perceptions of self-efficacy during the induction period

    NASA Astrophysics Data System (ADS)

    Gaither, Linda

    Sixty percent of America's teachers choose traditional baccalaureate programs while the remaining choose one of several alternative pathways. While certification/training is certainly important to preparing effective teachers, other research indicates that teacher efficacy serves as the foundation of teacher behaviors and classroom practice. The purpose of this study ( N = 94 induction high school science teachers) was to determine the relationships between certification pathway and opportunities to observe modeling; between years of experience and personal teaching efficacy; and teachers' perceptions of what characteristics/ experiences best explain personal teaching efficacy. The Teacher Sense of Efficacy Scale was used in an on-line survey for Phase 1 (n = 91), to measure teacher self-efficacy. In Phase 2, a basic qualitative study was conducted using telephone interviews ( n = 2) and a focus group (n = 4) along with a series of short essay questions from the online survey (n = 91). The findings indicate a significant relationship (p = 0.01) between years of teaching and overall personal teaching-efficacy, student engagement, and instructional strategies; a relationship between opportunities to see modeling and certification pathway, where traditionally certified teachers had significantly more opportunities (p = 0.000); and a relationship between classroom management and opportunities to see modeling (p = 0.005). Qualitative analyses confirmed that traditionally-prepared teachers saw a range of "modeling" and model teachers; respondents related such opportunities to more effective teaching, especially in the realm of classroom management. As more teachers choose alternative certification, it is imperative that adequate opportunities to observe teaching strategies are modeled during the certification process and once teachers enter the classroom; they must have intrinsic and extrinsic support to be successful.

  11. Certifying an Irreducible 1024-Dimensional Photonic State Using Refined Dimension Witnesses.

    PubMed

    Aguilar, Edgar A; Farkas, Máté; Martínez, Daniel; Alvarado, Matías; Cariñe, Jaime; Xavier, Guilherme B; Barra, Johanna F; Cañas, Gustavo; Pawłowski, Marcin; Lima, Gustavo

    2018-06-08

    We report on a new class of dimension witnesses, based on quantum random access codes, which are a function of the recorded statistics and that have different bounds for all possible decompositions of a high-dimensional physical system. Thus, it certifies the dimension of the system and has the new distinct feature of identifying whether the high-dimensional system is decomposable in terms of lower dimensional subsystems. To demonstrate the practicability of this technique, we used it to experimentally certify the generation of an irreducible 1024-dimensional photonic quantum state. Therefore, certifying that the state is not multipartite or encoded using noncoupled different degrees of freedom of a single photon. Our protocol should find applications in a broad class of modern quantum information experiments addressing the generation of high-dimensional quantum systems, where quantum tomography may become intractable.

  12. Certifying an Irreducible 1024-Dimensional Photonic State Using Refined Dimension Witnesses

    NASA Astrophysics Data System (ADS)

    Aguilar, Edgar A.; Farkas, Máté; Martínez, Daniel; Alvarado, Matías; Cariñe, Jaime; Xavier, Guilherme B.; Barra, Johanna F.; Cañas, Gustavo; Pawłowski, Marcin; Lima, Gustavo

    2018-06-01

    We report on a new class of dimension witnesses, based on quantum random access codes, which are a function of the recorded statistics and that have different bounds for all possible decompositions of a high-dimensional physical system. Thus, it certifies the dimension of the system and has the new distinct feature of identifying whether the high-dimensional system is decomposable in terms of lower dimensional subsystems. To demonstrate the practicability of this technique, we used it to experimentally certify the generation of an irreducible 1024-dimensional photonic quantum state. Therefore, certifying that the state is not multipartite or encoded using noncoupled different degrees of freedom of a single photon. Our protocol should find applications in a broad class of modern quantum information experiments addressing the generation of high-dimensional quantum systems, where quantum tomography may become intractable.

  13. 42 CFR 405.2414 - Nurse practitioner, physician assistant, and certified nurse midwife services.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 2 2014-10-01 2014-10-01 false Nurse practitioner, physician assistant, and... practitioner, physician assistant, and certified nurse midwife services. (a) Professional services are payable..., physician assistant, or certified nurse midwife who is employed by, or receives compensation from, the RHC...

  14. Exponential gain of randomness certified by quantum contextuality

    NASA Astrophysics Data System (ADS)

    Um, Mark; Zhang, Junhua; Wang, Ye; Wang, Pengfei; Kim, Kihwan

    2017-04-01

    We demonstrate the protocol of exponential gain of randomness certified by quantum contextuality in a trapped ion system. The genuine randomness can be produced by quantum principle and certified by quantum inequalities. Recently, randomness expansion protocols based on inequality of Bell-text and Kochen-Specker (KS) theorem, have been demonstrated. These schemes have been theoretically innovated to exponentially expand the randomness and amplify the randomness from weak initial random seed. Here, we report the experimental evidence of such exponential expansion of randomness. In the experiment, we use three states of a 138Ba + ion between a ground state and two quadrupole states. In the 138Ba + ion system, we do not have detection loophole and we apply a methods to rule out certain hidden variable models that obey a kind of extended noncontextuality.

  15. The need to certify products to CDRH Regulations.

    PubMed

    Weiner, R

    1994-06-01

    Laser products that are sold in the United States are required to comply with the regulations published by the Center for Devices and Radiological Health (CDRH) within the US Food and Drug Administration [1]. The need to certify products is straightforward in most instances, however, the applicability of the regulations is not as clear for: lasers sold only to Original Equipment Manufacturers (OEMs) as components for incorporation into end-use products, end-use products that contain lasers which have already been certified by their manufacturers, and end-use products that are being imported into the US and that already comply with international laser safety standards. This article will discuss these applications in an attempt to clarify the need for certification by laser product manufacturers and importers. The discussion applies equally for lasers and laser systems.

  16. 7 CFR 205.103 - Recordkeeping by certified operations.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 205.103 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) ORGANIC FOODS PRODUCTION ACT PROVISIONS NATIONAL ORGANIC PROGRAM Applicability § 205.103 Recordkeeping by certified...

  17. 25 CFR 170.506 - What are the minimum qualifications for certified bridge inspectors?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false What are the minimum qualifications for certified bridge... Program Facilities Bridge Inspection § 170.506 What are the minimum qualifications for certified bridge inspectors? The person responsible for the bridge inspection team must meet the qualifications for bridge...

  18. Supporting and Fostering the Development of Alternatively Certified Teachers: Creating a Collaborative Community

    ERIC Educational Resources Information Center

    Preach, Deborah

    2013-01-01

    First-year alternatively certified teachers face significant challenges as they attempt to address the complexities of classroom teaching, particularly when they are assigned to teach in urban school settings. As the number of alternatively certified teachers continues to increase, it is important to provide them with professional development…

  19. The cryogenic storage ring CSR

    NASA Astrophysics Data System (ADS)

    von Hahn, R.; Becker, A.; Berg, F.; Blaum, K.; Breitenfeldt, C.; Fadil, H.; Fellenberger, F.; Froese, M.; George, S.; Göck, J.; Grieser, M.; Grussie, F.; Guerin, E. A.; Heber, O.; Herwig, P.; Karthein, J.; Krantz, C.; Kreckel, H.; Lange, M.; Laux, F.; Lohmann, S.; Menk, S.; Meyer, C.; Mishra, P. M.; Novotný, O.; O'Connor, A. P.; Orlov, D. A.; Rappaport, M. L.; Repnow, R.; Saurabh, S.; Schippers, S.; Schröter, C. D.; Schwalm, D.; Schweikhard, L.; Sieber, T.; Shornikov, A.; Spruck, K.; Sunil Kumar, S.; Ullrich, J.; Urbain, X.; Vogel, S.; Wilhelm, P.; Wolf, A.; Zajfman, D.

    2016-06-01

    An electrostatic cryogenic storage ring, CSR, for beams of anions and cations with up to 300 keV kinetic energy per unit charge has been designed, constructed, and put into operation. With a circumference of 35 m, the ion-beam vacuum chambers and all beam optics are in a cryostat and cooled by a closed-cycle liquid helium system. At temperatures as low as (5.5 ± 1) K inside the ring, storage time constants of several minutes up to almost an hour were observed for atomic and molecular, anion and cation beams at an energy of 60 keV. The ion-beam intensity, energy-dependent closed-orbit shifts (dispersion), and the focusing properties of the machine were studied by a system of capacitive pickups. The Schottky-noise spectrum of the stored ions revealed a broadening of the momentum distribution on a time scale of 1000 s. Photodetachment of stored anions was used in the beam lifetime measurements. The detachment rate by anion collisions with residual-gas molecules was found to be extremely low. A residual-gas density below 140 cm-3 is derived, equivalent to a room-temperature pressure below 10-14 mbar. Fast atomic, molecular, and cluster ion beams stored for long periods of time in a cryogenic environment will allow experiments on collision- and radiation-induced fragmentation processes of ions in known internal quantum states with merged and crossed photon and particle beams.

  20. The cryogenic storage ring CSR.

    PubMed

    von Hahn, R; Becker, A; Berg, F; Blaum, K; Breitenfeldt, C; Fadil, H; Fellenberger, F; Froese, M; George, S; Göck, J; Grieser, M; Grussie, F; Guerin, E A; Heber, O; Herwig, P; Karthein, J; Krantz, C; Kreckel, H; Lange, M; Laux, F; Lohmann, S; Menk, S; Meyer, C; Mishra, P M; Novotný, O; O'Connor, A P; Orlov, D A; Rappaport, M L; Repnow, R; Saurabh, S; Schippers, S; Schröter, C D; Schwalm, D; Schweikhard, L; Sieber, T; Shornikov, A; Spruck, K; Sunil Kumar, S; Ullrich, J; Urbain, X; Vogel, S; Wilhelm, P; Wolf, A; Zajfman, D

    2016-06-01

    An electrostatic cryogenic storage ring, CSR, for beams of anions and cations with up to 300 keV kinetic energy per unit charge has been designed, constructed, and put into operation. With a circumference of 35 m, the ion-beam vacuum chambers and all beam optics are in a cryostat and cooled by a closed-cycle liquid helium system. At temperatures as low as (5.5 ± 1) K inside the ring, storage time constants of several minutes up to almost an hour were observed for atomic and molecular, anion and cation beams at an energy of 60 keV. The ion-beam intensity, energy-dependent closed-orbit shifts (dispersion), and the focusing properties of the machine were studied by a system of capacitive pickups. The Schottky-noise spectrum of the stored ions revealed a broadening of the momentum distribution on a time scale of 1000 s. Photodetachment of stored anions was used in the beam lifetime measurements. The detachment rate by anion collisions with residual-gas molecules was found to be extremely low. A residual-gas density below 140 cm(-3) is derived, equivalent to a room-temperature pressure below 10(-14) mbar. Fast atomic, molecular, and cluster ion beams stored for long periods of time in a cryogenic environment will allow experiments on collision- and radiation-induced fragmentation processes of ions in known internal quantum states with merged and crossed photon and particle beams.