Normal reference values of diastolic strain rate in healthy individuals: Chronological trends and the comparison according to genders.

PubMed

Sun, Byung Joo; Park, Jae-Hyeong; Kim, Jeongai; Choi, Jin-Oh; Lee, Ju-Hee; Shin, Mi-Seung; Kim, Mi-Jeong; Jung, Hae Ok; Park, Jeong Rang; Sohn, Il Suk; Kim, Hyungseop; Kim, Hyung-Kwan; Cho, Goo-Yeong; Park, Jin-Sun; Shim, Chi Young; Shin, Sung Hee; Kim, Kye Hun; Kim, Woo-Shik; Park, Seung Woo

2018-06-19

Recently, the diastolic strain rate (DSR) utilizing speckle-tracking echocardiography has been proposed as a novel parameter for left ventricular diastolic function. We aimed to present normal reference data for those in a large-sized, selected group of healthy individuals. The current study was a part of the Normal echOcardiogRaphic Measurements in KoreAn popuLation (NORMAL), a prospective nationwide survey from 23 centers in Korea. We analyzed 447 subjects (age 48 ± 15 years, 234 females) without any history of cardiovascular disease and presented the early and late DSRs (SR e and SR a , respectively) in a total and gender-/age-specified groups. Among the total subjects, the mean SR e and SR a were 1.6 ± 0.4 S -1 and 0.8 ± 0.3 S -1 , respectively. With increasing age, there were significant trends of decreasing SR e and increasing SR a . Although both gender groups showed comparable age, the female group presented significantly higher SR e compared to male subjects with age of 20-59 years, which diminished after the age of 60 years. However, the SR a was comparable between genders in all age groups. On multiple linear regression, age showed independent associations with both SR e (β = -0.132, P = .010) and SR a (β = 0.440, P < .001), whereas gender did not show any association with SR e or SR a . We present normal reference data of a novel parameter, DSR, in a large-sized selected group with healthy Korean subjects. Additionally, we present significant age-related changes both in SR e and SR a without the impact of their gender. © 2018 Wiley Periodicals, Inc.

Polarization-Engineered Ga-Face GaN-Based Heterostructures for Normally-Off Heterostructure Field-Effect Transistors

NASA Astrophysics Data System (ADS)

Kim, Hyeongnam; Nath, Digbijoy; Rajan, Siddharth; Lu, Wu

2013-01-01

Polarization-engineered Ga-face GaN-based heterostructures with a GaN cap layer and an AlGaN/ p-GaN back barrier have been designed for normally-off field-effect transistors (FETs). The simulation results show that an unintentionally doped GaN cap and p-GaN layer in the buffer primarily deplete electrons in the channel and the Al0.2Ga0.8N back barrier helps to pinch off the channel. Experimentally, we have demonstrated a normally-off GaN-based field-effect transistor on the designed GaN cap/Al0.3Ga0.7N/GaN channel/Al0.2Ga0.8N/ p-GaN/GaN heterostructure. A positive threshold voltage of 0.2 V and maximum transconductance of 2.6 mS/mm were achieved for 80- μm-long gate devices. The device fabrication process does not require a dry etching process for gate recessing, while highly selective etching of the GaN cap against a very thin Al0.3GaN0.7N top barrier has to be performed to create a two-dimensional electron gas for both the ohmic and access regions. A self-aligned, selective etch of the GaN cap in the access region is introduced, using the gate metal as an etch mask. The absence of gate recess etching is promising for uniform and repeatable threshold voltage control in normally-off AlGaN/GaN heterostructure FETs for power switching applications.

Nitrogen trends in rivers of the conterminous U.S. in the context of land use and sources

NASA Astrophysics Data System (ADS)

Stets, E.; Sprague, L. A.

2017-12-01

Tremendous efforts have been undertaken to improve the quality of water throughout the United States over the past several decades. The goal of decreasing nitrogen concentrations and fluxes from U.S. rivers has had mixed success and the results are often difficult to quantify. The U.S. Geological Survey has undertaken a study to describe trends in water quality at hundreds of river and stream locations in the conterminous U.S. using a broad data set from national, state, local, and tribal entities. This study represents the largest and most comprehensive analysis of trends in water quality in the U.S. to date. During the period 1992-2012, nitrate (NO3) decreased at 132 sites and increased at 88 sites. Total nitrogen (TN) decreased at 91 sites and increased at 55 sites. The median trend for both NO3 and TN was slightly downward, at -0.04 and -0.11 mg N L-1, respectively. For both NO3 and TN, downward trends were more common in agricultural and urban sites while upward trends were more common at undeveloped sites. Decreases in TN were largest in rivers for which NO3 was a large proportion of TN, which is indicative of significant anthropogenic nitrogen inputs. Across all sites and land use types, trends in TN were highly correlated with trends in NO3, suggesting that changes in NO3 have been a large contributor to TN trends. While overall the largest decreases in NO3 and TN primarily occurred in heavily agricultural areas, decreases were also common in watersheds with higher percentage urban development. Likewise, the largest decreases in NO3 deposition were found in more developed watersheds, suggesting that decreasing atmospheric deposition may be related to NO3 trends at the more developed locations. Despite these improvements, fluxes of nitrogen to the coastal ocean have been largely static over the past several decades, underscoring the continuing need for nutrient management in many parts of the conterminous U.S.

El Nino during the 1990s: Harbinger of Climatic Change or Normal Fluctuation?

NASA Technical Reports Server (NTRS)

Wilson, Robert M.

1999-01-01

Today, El Nino refers to the extreme warming episodes of the globally effective, coupled ocean-atmospheric interaction commonly known as ENSO (i.e., "El Nino-Southern Oscillation"). Concerning its observed decadal frequency and severity, El Nino during the 1990s has often been regarded as being anomalous. Results of analysis reported herein, however, appear to mitigate this belief. For example, regarding the frequency and severity of El Nino, the decade of the 1990s is found to compare quite favorably with that of preceding decades. Hence, the 1990s probably should not be regarded as being anomalous. On the other hand, the number of El Nino-related months per decade has sharply increased during the 1990s, as compared to the preceding four decades, hinting of a marginally significant upward trend. Perhaps, this is an indication that the Earth is now experiencing an ongoing global climatic change. Continued vigilance during the new millennium, therefore, is of paramount importance for determining whether or not this "hint" of a global change is real or if it merely reflects a normal fluctuation of climate.

Version 8 SBUV Ozone Profile Trends Compared with Trends from a Zonally Averaged Chemical Model

NASA Technical Reports Server (NTRS)

Rosenfield, Joan E.; Frith, Stacey; Stolarski, Richard

2004-01-01

Linear regression trends for the years 1979-2003 were computed using the new Version 8 merged Solar Backscatter Ultraviolet (SBUV) data set of ozone profiles. These trends were compared to trends computed using ozone profiles from the Goddard Space Flight Center (GSFC) zonally averaged coupled model. Observed and modeled annual trends between 50 N and 50 S were a maximum in the higher latitudes of the upper stratosphere, with southern hemisphere (SH) trends greater than northern hemisphere (NH) trends. The observed upper stratospheric maximum annual trend is -5.5 +/- 0.9 % per decade (1 sigma) at 47.5 S and -3.8 +/- 0.5 % per decade at 47.5 N, to be compared with the modeled trends of -4.5 +/- 0.3 % per decade in the SH and -4.0 +/- 0.2% per decade in the NH. Both observed and modeled trends are most negative in winter and least negative in summer, although the modeled seasonal difference is less than observed. Model trends are shown to be greatest in winter due to a repartitioning of chlorine species and the increasing abundance of chlorine with time. The model results show that trend differences can occur depending on whether ozone profiles are in mixing ratio or number density coordinates, and on whether they are recorded on pressure or altitude levels.

Υ production in U + U collisions at √{sN N}=193 GeV measured with the STAR experiment

NASA Astrophysics Data System (ADS)

Adamczyk, L.; Adkins, J. K.; Agakishiev, G.; Aggarwal, M. M.; Ahammed, Z.; Alekseev, I.; Anderson, D. M.; Aoyama, R.; Aparin, A.; Arkhipkin, D.; Aschenauer, E. C.; Ashraf, M. U.; Attri, A.; Averichev, G. S.; Bai, X.; Bairathi, V.; Bellwied, R.; Bhasin, A.; Bhati, A. K.; Bhattarai, P.; Bielcik, J.; Bielcikova, J.; Bland, L. C.; Bordyuzhin, I. G.; Bouchet, J.; Brandenburg, J. D.; Brandin, A. V.; Bunzarov, I.; Butterworth, J.; Caines, H.; Calderón de la Barca Sánchez, M.; Campbell, J. M.; Cebra, D.; Chakaberia, I.; Chaloupka, P.; Chang, Z.; Chatterjee, A.; Chattopadhyay, S.; Chen, J. H.; Chen, X.; Cheng, J.; Cherney, M.; Christie, W.; Contin, G.; Crawford, H. J.; Das, S.; De Silva, L. C.; Debbe, R. R.; Dedovich, T. G.; Deng, J.; Derevschikov, A. A.; Didenko, L.; Dilks, C.; Dong, X.; Drachenberg, J. L.; Draper, J. E.; Du, C. M.; Dunkelberger, L. E.; Dunlop, J. C.; Efimov, L. G.; Engelage, J.; Eppley, G.; Esha, R.; Esumi, S.; Evdokimov, O.; Eyser, O.; Fatemi, R.; Fazio, S.; Federic, P.; Fedorisin, J.; Feng, Z.; Filip, P.; Finch, E.; Fisyak, Y.; Flores, C. E.; Fulek, L.; Gagliardi, C. A.; Garand, D.; Geurts, F.; Gibson, A.; Girard, M.; Greiner, L.; Grosnick, D.; Gunarathne, D. S.; Guo, Y.; Gupta, A.; Gupta, S.; Guryn, W.; Hamad, A. I.; Hamed, A.; Haque, R.; Harris, J. W.; He, L.; Heppelmann, S.; Heppelmann, S.; Hirsch, A.; Hoffmann, G. W.; Horvat, S.; Huang, H. Z.; Huang, B.; Huang, T.; Huang, X.; Huck, P.; Humanic, T. J.; Igo, G.; Jacobs, W. W.; Jentsch, A.; Jia, J.; Jiang, K.; Jowzaee, S.; Judd, E. G.; Kabana, S.; Kalinkin, D.; Kang, K.; Kauder, K.; Ke, H. W.; Keane, D.; Kechechyan, A.; Khan, Z.; Kikoła, D. P.; Kisel, I.; Kisiel, A.; Kochenda, L.; Koetke, D. D.; Kosarzewski, L. K.; Kraishan, A. F.; Kravtsov, P.; Krueger, K.; Kumar, L.; Lamont, M. A. C.; Landgraf, J. M.; Landry, K. D.; Lauret, J.; Lebedev, A.; Lednicky, R.; Lee, J. H.; Li, Y.; Li, C.; Li, X.; Li, W.; Li, X.; Lin, T.; Lisa, M. A.; Liu, F.; Liu, Y.; Ljubicic, T.; Llope, W. J.; Lomnitz, M.; Longacre, R. S.; Luo, X.; Luo, S.; Ma, G. L.; Ma, R.; Ma, L.; Ma, Y. G.; Magdy, N.; Majka, R.; Manion, A.; Margetis, S.; Markert, C.; Matis, H. S.; McDonald, D.; McKinzie, S.; Meehan, K.; Mei, J. C.; Miller, Z. W.; Minaev, N. G.; Mioduszewski, S.; Mishra, D.; Mohanty, B.; Mondal, M. M.; Morozov, D. A.; Mustafa, M. K.; Nandi, B. K.; Nasim, Md.; Nayak, T. K.; Nigmatkulov, G.; Niida, T.; Nogach, L. V.; Nonaka, T.; Novak, J.; Nurushev, S. B.; Odyniec, G.; Ogawa, A.; Oh, K.; Okorokov, V. A.; Olvitt, D.; Page, B. S.; Pak, R.; Pan, Y. X.; Pandit, Y.; Panebratsev, Y.; Pawlik, B.; Pei, H.; Perkins, C.; Pile, P.; Pluta, J.; Poniatowska, K.; Porter, J.; Posik, M.; Poskanzer, A. M.; Pruthi, N. K.; Przybycien, M.; Putschke, J.; Qiu, H.; Quintero, A.; Ramachandran, S.; Ray, R. L.; Reed, R.; Rehbein, M. J.; Ritter, H. G.; Roberts, J. B.; Rogachevskiy, O. V.; Romero, J. L.; Roth, J. D.; Ruan, L.; Rusnak, J.; Rusnakova, O.; Sahoo, N. R.; Sahu, P. K.; Sakrejda, I.; Salur, S.; Sandweiss, J.; Sarkar, A.; Schambach, J.; Scharenberg, R. P.; Schmah, A. M.; Schmidke, W. B.; Schmitz, N.; Seger, J.; Seyboth, P.; Shah, N.; Shahaliev, E.; Shanmuganathan, P. V.; Shao, M.; Sharma, M. K.; Sharma, A.; Sharma, B.; Shen, W. Q.; Shi, Z.; Shi, S. S.; Shou, Q. Y.; Sichtermann, E. P.; Sikora, R.; Simko, M.; Singha, S.; Skoby, M. J.; Smirnov, D.; Smirnov, N.; Solyst, W.; Song, L.; Sorensen, P.; Spinka, H. M.; Srivastava, B.; Stanislaus, T. D. S.; Stepanov, M.; Stock, R.; Strikhanov, M.; Stringfellow, B.; Sugiura, T.; Sumbera, M.; Summa, B.; Sun, Y.; Sun, Z.; Sun, X. M.; Surrow, B.; Svirida, D. N.; Tang, Z.; Tang, A. H.; Tarnowsky, T.; Tawfik, A.; Thäder, J.; Thomas, J. H.; Timmins, A. R.; Tlusty, D.; Todoroki, T.; Tokarev, M.; Trentalange, S.; Tribble, R. E.; Tribedy, P.; Tripathy, S. K.; Tsai, O. D.; Ullrich, T.; Underwood, D. G.; Upsal, I.; Van Buren, G.; van Nieuwenhuizen, G.; Varma, R.; Vasiliev, A. N.; Vertesi, R.; Videbæk, F.; Vokal, S.; Voloshin, S. A.; Vossen, A.; Wang, G.; Wang, J. S.; Wang, F.; Wang, Y.; Wang, Y.; Webb, J. C.; Webb, G.; Wen, L.; Westfall, G. D.; Wieman, H.; Wissink, S. W.; Witt, R.; Wu, Y.; Xiao, Z. G.; Xie, G.; Xie, W.; Xin, K.; Xu, Z.; Xu, H.; Xu, N.; Xu, J.; Xu, Y. F.; Xu, Q. H.; Yang, Y.; Yang, Y.; Yang, S.; Yang, Q.; Yang, Y.; Yang, C.; Ye, Z.; Ye, Z.; Yi, L.; Yip, K.; Yoo, I.-K.; Yu, N.; Zbroszczyk, H.; Zha, W.; Zhang, J.; Zhang, Z.; Zhang, J.; Zhang, S.; Zhang, X. P.; Zhang, J. B.; Zhang, Y.; Zhang, S.; Zhao, J.; Zhong, C.; Zhou, L.; Zhu, X.; Zoulkarneeva, Y.; Zyzak, M.; STAR Collaboration

2016-12-01

We present a measurement of the inclusive production of Υ mesons in U+U collisions at √{sN N}=193 GeV at midrapidity (|y |<1 ). Previous studies in central Au+Au collisions at √{sN N}=200 GeV show a suppression of Υ (1S+2S+3S) production relative to expectations from the Υ yield in p+p collisions scaled by the number of binary nucleon-nucleon collisions (Ncoll), with an indication that the Υ (1S) state is also suppressed. The present measurement extends the number of participant nucleons in the collision (Npart) by 20% compared to Au+Au collisions, and allows us to study a system with higher energy density. We observe a suppression in both the Υ (1 S +2 S +3 S ) and Υ (1 S ) yields in central U+U data, which consolidates and extends the previously observed suppression trend in Au+Au collisions.

Normality of different orders for Cantor series expansions

NASA Astrophysics Data System (ADS)

Airey, Dylan; Mance, Bill

2017-10-01

Let S \\subseteq {N} have the property that for each k \\in S the set (S - k) \\cap {N} \\setminus S has asymptotic density 0. We prove that there exists a basic sequence Q where the set of numbers Q-normal of all orders in S but not Q-normal of all orders not in S has full Hausdorff dimension. If the function \

Snow in Castile-León: trends and variability

NASA Astrophysics Data System (ADS)

Merino, A.; Campos, L.; López, L.; García-Ortega, E.; Sánchez, J. L.; Marcos, J. L.; Guerrero-Higueras, A. M.

2012-04-01

The location of Castile and León, inside the Iberian Peninsula, in the Northwestern quadrant, determines, in large measure, the climatic conditions of its territory, granting it very characteristic traits, mostly in the mountainous areas. It is important to note that during a large part of the year, the region is under the influence of Jet Stream, and thus, gives way to very diverse dynamic situations, which turn into different and heterogeneous types of weather. So, in many areas of the region, especially in the most elevated areas, these synoptic and mesoscale situations generate snow precipitation. We should point out that snowfall is one of the principal meteorological risks of Castile and León. Thus, on average, in some mountainous areas there are more than 40 events of snowfall registered annually, with the month of January being the month in which the highest frequency of snowfall appears. The social repercussions of this snowfall are represented in the isolation of places, essentially mountainous, highways being blocked, increase in traffic accidents, etc. As proof of this, it is this type of episode that receives ample coverage by the media, which has a linear relationship with the social perception of risk. As such, the objective of the current work is to analyze the annual trend of days with snow in the different meteorological stations pertaining to AEMET placed in the Community. The period of study is from 1960-2010. Additionally, we have also evaluated trends in annual days of freezing temperature and annual absolute minimum temperature, with the objective of facilitating a meteorological interpretation of the trends obtained on days with snowfall. Finally, the results show that in the majority of stations, a significant negative trend in days with snowfall and annual days with freezing temperatures, and a positive trend in annual absolute minimum temperatures. However, we observed variability in the different regions in the area of study

Water-quality trends in the nation’s rivers and streams, 1972–2012—Data preparation, statistical methods, and trend results

USGS Publications Warehouse

Oelsner, Gretchen P.; Sprague, Lori A.; Murphy, Jennifer C.; Zuellig, Robert E.; Johnson, Henry M.; Ryberg, Karen R.; Falcone, James A.; Stets, Edward G.; Vecchia, Aldo V.; Riskin, Melissa L.; De Cicco, Laura A.; Mills, Taylor J.; Farmer, William H.

2017-04-04

Since passage of the Clean Water Act in 1972, Federal, State, and local governments have invested billions of dollars to reduce pollution entering rivers and streams. To understand the return on these investments and to effectively manage and protect the Nation’s water resources in the future, we need to know how and why water quality has been changing over time. As part of the National Water-Quality Assessment Project, of the U.S. Geological Survey’s National Water-Quality Program, data from the U.S. Geological Survey, along with multiple other Federal, State, Tribal, regional, and local agencies, have been used to support the most comprehensive assessment conducted to date of surface-water-quality trends in the United States. This report documents the methods used to determine trends in water quality and ecology because these methods are vital to ensuring the quality of the results. Specific objectives are to document (1) the data compilation and processing steps used to identify river and stream sites throughout the Nation suitable for water-quality, pesticide, and ecology trend analysis, (2) the statistical methods used to determine trends in target parameters, (3) considerations for water-quality, pesticide, and ecology data and streamflow data when modeling trends, (4) sensitivity analyses for selecting data and interpreting trend results with the Weighted Regressions on Time, Discharge, and Season method, and (5) the final trend results at each site. The scope of this study includes trends in water-quality concentrations and loads (nutrient, sediment, major ion, salinity, and carbon), pesticide concentrations and loads, and metrics for aquatic ecology (fish, invertebrates, and algae) for four time periods: (1) 1972–2012, (2) 1982–2012, (3) 1992–2012, and (4) 2002–12. In total, nearly 12,000 trends in concentration, load, and ecology metrics were evaluated in this study; there were 11,893 combinations of sites, parameters, and trend periods. The

Evaluation of the ASOS impact on climatic normals and assessment of variable-length time periods in calculation of normals

NASA Astrophysics Data System (ADS)

Kauffman, Chad Matthew

The temperature and precipitation that describe the norm of daily, monthly, and seasonal climate conditions are ``climate normals.'' They are usually calculated based on climate data covering a 30-year period, and updated in every 10 years. The next update will take place in year 2001. Because of the advent of the Automated Surface Observations Systems (ASOS) beginning in early 1990s and recognized temperature bias between ASOS and the conventional temperature sensors there is an uncertainty of how the ASOS data should be used to calculate the 1971-2000 temperature normal. This study examined the uncertainty and offered a method to minimize it. It showed that the ASOS bias has a measurable impact on the new 30-year temperature normal. The impact varies among stations and climate regions. Some stations with a cooling trend in ASOS temperature have a cooler normal for their temperature, while others with a warming trend have a warmer normal for temperature. These quantitative evaluations of ASOS effect for stations and regions can be used to reduce ASOS bias in temperature normals. This study also evaluated temperature normals for different length periods and compared them to the 30-year normal. It showed that the difference between the normals, is smaller in maritime climate than in continental temperate climate. In the former, the six- year normal describes a similar temperature variation as the 30-year normal does. In the latter, the 18-year normal starts to resemble the temperature variation that the 30-year normal describes. These results provide a theoretical basis for applying different normals in different regions. The study further compared temperature normal for different periods and identified a seasonal shift in climate change in the southwestern U.S. where the summer maximum temperature has shifted to a late summer month and the winter minimum temperature shifted to an early winter month in the past 30 years.

Spectra of normal and nutrient-deficient maize leaves

NASA Technical Reports Server (NTRS)

Al-Abbas, A. H.; Barr, R.; Hall, J. D.; Crane, F. L.; Baumgardner, M. F.

1973-01-01

Reflectance, transmittance and absorptance spectra of normal and six types of nutrient-deficient (N, P, K, S, Mg, and Ca) maize (Zea mays L.) leaves were analyzed at 30 selected wavelengths from 500 to 2600 nm. The analysis of variance showed significant differences in reflectance, transmittance and absorptance in the visible wavelengths among leaf numbers 3, 4, and 5, among the seven treatments, and among the interactions of leaf number and treatments. In the infrared wavelengths only treatments produced significant differences. The chlorophyll content of leaves was reduced in all nutrient-deficient treatments. Percent moisture was increased in S-, Mg-, and N-deficiencies. Polynomial regression analysis of leaf thickness and leaf moisture content showed that these two variables were significantly and directly related. Leaves from the P- and Ca-deficient plants absorbed less energy in the near infrared than the normal plants; S-, Mg-, K-, and N-deficient leaves absorbed more than the normal. Both S- and N-deficient leaves had higher temperatues than normal maize leaves.

U.S. wood pallet material use trends

Treesearch

Philip A. Araman; Robert J. Bush; E.Bradley Hager

2010-01-01

A series of five studies conducted by the Virginia Tech Department of Wood Science and Forest Products, in collaboration with the USDA – Forest Service (Blacksburg, Virginia), have tracked activity in the U.S. wood pallet and container industry between 1992 and 2006. The studies determined trends in wood use and pallet production within the industry, both new and...

U.S. shale gas trends - economic and global implications

NASA Astrophysics Data System (ADS)

Murphy, T.

2016-09-01

Natural gas from shale has moved the U.S., and North America more broadly, to become one of the largest producers of the commodity worldwide. Large technological gains have allowed reservoirs of unconventional hydrocarbons to become commercially viable to extract and market. The addition of this growing supply into the global marketplace, has upended longstanding trading patterns, and created new economic outcomes worth noting. This paper will discuss the recent trends of shale energy development in the U.S., the impact it is having on domestic and international markets, and the implications as the world shifts to a new low carbon energy paradigm. It will cover changes in workforce, midstream build out, power generation trends, petrochemicals, and emerging LNG export capacities.

Decadal stream water quality trends under varying climate, land use, and hydrogeochemical setting in, Iowa, USA

NASA Astrophysics Data System (ADS)

Green, Christopher; Bekins, Barbara; Kalkhoff, Stephen; Hirsch, Robert; Liao, Lixia; Barnes, Kimberlee

2015-04-01

Understanding how nitrogen fluxes respond to changes in agricultural practices and climatic variations is important for improving water quality in agricultural settings. In the central United States, intensification of corn cropping in support of ethanol production led to increases in N application rates in the 2000s during a period including both extreme dry and wet conditions. To examine the effect of these recent changes, a study was conducted on surface water quality in 10 major Iowa Rivers. Long term (~20 to 30 years) water quality and flow data were analyzed with Weighted Regression on Time, Discharge and Season (WRTDS), a statistical method that provides internally consistent estimates of the concentration history and reveals decadal trends that are independent of random variations of stream flow from seasonal averages. Trends of surface water quality showed constant or decreasing flow-normalized concentrations of nitrate+nitrite-N from 2000 to 2012 in all basins. To evaluate effects of annual discharge and N loading on these trends, multiple conceptual models were developed and calibrated to annual concentrations. The recent declining concentration trends can be attributed to both very high and very low streamflow discharge in the 2000's and to the long (e.g. 8-year) subsurface residence times in some basins. Dilution of surface water nitrate and depletion of stored nitrate may occur in years with very high discharge. Limited transport of N to streams and accumulation of stored N may occur in years with very low discharge. Central Iowa basins showed the greatest reduction in concentrations, likely because extensive tile-drains limit the effective volumes for storage of N and reduce residence times, and because the glacial sediments in these basins promote denitrification. Changes in nitrogen fluxes resulting from ethanol production and other factors will likely be delayed for years or decades in peripheral basins of Iowa, and may be obscured in the central

Trends in the normalized difference vegetation index (NDVI) associated with urban development in arctic and subarctic Western Siberia

NASA Astrophysics Data System (ADS)

Outten, S.; Miles, V.; Ezau, I.

2015-12-01

Changes in normalized difference vegetation index (NDVI) in the high Arctic have been reliably documented, with widespread "greening" (increase in NDVI), specifically along the northern rim of Eurasia and Alaska. Whereas in West Siberia south of 65N, widespread "browning" (decrease in NDVI) has been noted, although the causes remain largely unclear. In this study we report results of statistical analysis of the spatial and temporal changes in NDVI around 28 major urban areas in the arctic and subarctic Western Siberia. Exploration and exploitation of oil and gas reserves has led to rapid industrialization and urban development in the region. This development has significant impact on the environment and particularly in the vegetation cover in and around the urbanized areas. The analysis is based on 15 years (2000-2014) of high-resolution (250 m) Moderate Resolution Imaging Spectroradiometer (MODIS) data acquired for summer months (June through August) over the entire arctic and subarctic Western Siberian region. The analysis shows that the NDVI background trends are generally in agreement with the trends reported in previous coarse-resolution NDVI studies. Our study reveals greening over the arctic (tundra and tundra-forest) part of the region. Simultaneously, the southern (boreal taiga forest) part is browning, with the more densely vegetation areas or areas with highest NDVI, particularly along Ob River showing strong negative trend. The unexpected and interesting finding of the study is statistically robust indication of the accelerated increase of NDVI ("greening") in the older urban areas. Many Siberian cities become greener even against the decrease in the NDVI background. Moreover, interannual variations of urban NDVI are not coherent with the NDVI background variability. We also find that in tundra zones, NDVI values are higher in a 5-10 km buffer zone around the city edge than in rural areas (40 km distance from the city edge), and in taiga in a 5-10 km

ZnS-Based ZnSTe:N/n-ZnS Light-Emitting Diodes

NASA Astrophysics Data System (ADS)

Ichino, Kunio; Kojima, Takahiro; Obata, Shunsuke; Kuroyanagi, Takuma; Nakazawa, Shoichi; Kashiyama, Shota

2013-11-01

ZnS1-xTex:N/n-ZnS diodes have been fabricated in an attempt to convert ZnS into p-type by Te incorporation and the resulting upward shift of the valence band maximum. The diodes exhibit clear rectification in the current-voltage characteristic and a peak of the electron-beam-induced current at the ZnS1-xTex:N/n-ZnS interface. Furthermore, a ZnS0.85Te0.15:N/n-ZnS diode exhibits blue-green electroluminescence due to self-activated emission in n-ZnS at 290 K under a forward current. These results suggest p-type conduction in ZnS1-xTex:N, and thus the LED operation of a ZnS-based pn-junction.

Υ production in U + U collisions at s N N = 193 GeV measured with the STAR experiment

DOE PAGES

Adamczyk, L.

2016-12-15

We present a measurement of the inclusive production of ¡ mesons in U+U collisions at √sNN = 193 GeV at mid-rapidity (|y| < 1). Previous studies in central Au+Au collisions at √sNN = 200 GeV show a suppression of ¡(1S+2S+3S) production relative to expectations from the ¡ yield in p+p collisions scaled by the number of binary nucleon-nucleon collisions (N coll), with an indication that the ¡(1S) state is also suppressed. The present measurement extends the number of participant nucleons in the collision (N part) by 20% compared to Au+Au collisions, and allows us to study a system with highermore » energy density. We observe a suppression in both the ¡(1S+2S+3S) and ¡(1S) yields in central U+U data, which consolidates and extends the previously observed suppression trend in Au+Au collisions.« less

New astrophysical S factor for the {sup 15}N(p,{gamma}){sup 16}O reaction via the asymptotic normalization coefficient (ANC) method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mukhamedzhanov, A. M.; Gagliardi, C. A.; Goldberg, V. Z.

2008-07-15

The {sup 15}N(p,{gamma}){sup 16}O reaction provides a path from the CN cycle to the CNO bi-cycle and CNO tri-cycle. The measured astrophysical factor for this reaction is dominated by resonant capture through two strong J{sup {pi}}=1{sup -} resonances at E{sub R}=312 and 962 keV and direct capture to the ground state. Asymptotic normalization coefficients (ANCs) for the ground and seven excited states in {sup 16}O were extracted from the comparison of experimental differential cross sections for the {sup 15}N({sup 3}He,d){sup 16}O reaction with distorted-wave Born approximation calculations. Using these ANCs and proton and {alpha} resonance widths determined from an R-matrixmore » fit to the data from the {sup 15}N(p,{alpha}){sup 12}C reaction, we carried out an R-matrix calculation to obtain the astrophysical factor for the {sup 15}N(p,{gamma}){sup 16}O reaction. The results indicate that the direct capture contribution was previously overestimated. We find the astrophysical factor to be S(0)=36.0{+-}6.0 keV b, which is about a factor of 2 lower than the presently accepted value. We conclude that for every 2200{+-}300 cycles of the main CN cycle one CN catalyst is lost due to this reaction.« less

Time-varying trends of global vegetation activity

NASA Astrophysics Data System (ADS)

Pan, N.; Feng, X.; Fu, B.

2016-12-01

Vegetation plays an important role in regulating the energy change, water cycle and biochemical cycle in terrestrial ecosystems. Monitoring the dynamics of vegetation activity and understanding their driving factors have been an important issue in global change research. Normalized Difference Vegetation Index (NDVI), an indicator of vegetation activity, has been widely used in investigating vegetation changes at regional and global scales. Most studies utilized linear regression or piecewise linear regression approaches to obtain an averaged changing rate over a certain time span, with an implicit assumption that the trend didn't change over time during that period. However, no evidence shows that this assumption is right for the non-linear and non-stationary NDVI time series. In this study, we adopted the multidimensional ensemble empirical mode decomposition (MEEMD) method to extract the time-varying trends of NDVI from original signals without any a priori assumption of their functional form. Our results show that vegetation trends are spatially and temporally non-uniform during 1982-2013. Most vegetated area exhibited greening trends in the 1980s. Nevertheless, the area with greening trends decreased over time since the early 1990s, and the greening trends have stalled or even reversed in many places. Regions with browning trends were mainly located in southern low latitudes in the 1980s, whose area decreased before the middle 1990s and then increased at an accelerated rate. The greening-to-browning reversals were widespread across all continents except Oceania (43% of the vegetated areas), most of which happened after the middle 1990s. In contrast, the browning-to-greening reversals occurred in smaller area and earlier time. The area with monotonic greening and browning trends accounted for 33% and 5% of the vegetated area, respectively. By performing partial correlation analyses between NDVI and climatic elements (temperature, precipitation and cloud cover

Long-term trends in railroad service and capacity for U.S. agriculture

DOT National Transportation Integrated Search

2000-11-01

In this paper, the long-term trends in railroad services and capacity for U.S. agriculture are identified and described, particularly in terms of what these trends portend for agricultural shippers absent any change in the economically deregulated en...

An Ecologic Study of Trends in the Prevalence of Myopia in Chinese Adults in Singapore Born from the 1920s to 1980s.

PubMed

Sensaki, Sonoko; Sabanayagam, Charumathi; Verkicharla, Pavan K; Awodele, Adeola; Tan, Kok Hian; Chia, Audrey; Saw, Seang Mei

2017-06-01

This study aimed to investigate secular trends in the prevalence of myopia over 6 decades (from the 1920s to 1980s) in Chinese adults in Singapore. Parental myopia prevalence was estimated using a parent-completed questionnaire in paediatric cohorts that included: 1) The Singapore Cohort Of Risk factors for Myopia (SCORM), 2) The Strabismus, Amblyopia and Refractive Error in Singaporean Children (STARS), and 3) The Growing Up in Singapore Towards healthy Outcomes (GUSTO). Published estimates for myopia prevalence from 5 adult studies in Singapore were reviewed. Secular trends in the prevalence of myopia were correlated with changes in the education system. The prevalence of parental myopia in SCORM (n = 2943), STARS (n = 4938), and GUSTO (n = 1072) was 47.8%, 53.4%, and 73.4%, respectively; corresponding calendar years these parents might have started schooling were 1966, 1973, and 1983 (born in 1960, 1967, and 1977), respectively. Mean age of parents was 41.3, 40.1, and 33.4 years, respectively. Prevalence of myopia in adult studies in persons who started elementary school in 1928, 1934, 1938, 1939, 1942, 1948, 1952, 1958, 1962, 1972, 1982, and 1995 were 36.4%, 39.7%, 30.0%, 31.5%, 33.0%, 26.4%, 32.5%, 48.7%, 39.4%, 52.0%, 82.2%, and 85.9%, respectively. During the past few decades, the prevalence of myopia increased rapidly, especially in persons who started elementary school after the 1980s (born after 1970). The education system was expanded after Singapore's independence in 1965, and the new education system was introduced in 1978. These changes, together with increasing intensive schooling, may have contributed to the increase in myopia prevalence.

Long-term streamflow trends on California’s north coast

Treesearch

J. Eli Asarian; Jeffrey D. Walker

2017-01-01

Using streamflow data from the U.S. Geological Survey, we assessed long-term (1953-2012) trends in streamflow on California’s North Coast including many sites in the redwood region. The study area spans from the Smith River to the Mattole River and includes the Eel and Klamath-Trinity basins. Antecedent Precipitation Index (API) is a time-weighted summary of...

Administrative trends in U.S. dental schools.

PubMed

Fu, Martin M; Rodriguez, Angel; Chen, Rebecca Y; Fu, Earl; Liao, Shu-Yi; Karimbux, Nadeem Y

2014-11-01

The aims of this study were to analyze the administrative trends in U.S. dental schools at the beginning and end of a thirteen-year period and to identify the predictive factors for those changes. Administrative trends were measured by the difference in the number of major administrative positions for 1997 and 2010 reported in American Dental Education Association (ADEA) and American Dental Association (ADA) publications. Secondary measures (program length, student enrollment, and tuition) were also gathered. The mean numbers of administrative positions per school significantly increased over the study period, while the mean number of clinical science departments per school significantly decreased. The change in the number of directors was positively correlated with the change in student enrollment, but inversely correlated with the change in number of vice/associate/assistant deans. The change in the number of clinical science departments was positively correlated with changes in student enrollment and out-of-state tuition, but inversely correlated with the change in in-state tuition. The number of all departments per U.S. dental school significantly decreased in this period. The schools that had consolidation of clinical science departments were less likely to have increases in student enrollment and out-of-state tuition, but more likely to have increases in in-state tuition.

Trends in Back-White Differentials in Dietary Intakes of U.S. Adults, 1971–2002

PubMed Central

Kant, Ashima K; Graubard, Barry I; Kumanyika, Shiriki K

2007-01-01

Background Disparities in the health status of blacks and whites have persisted despite considerable gains in improved health of the U.S. population. Tracking changes in black-white differentials in dietary attributes over time may help in understanding the contribution of diet to these disparities. Methods Data were used from four National Health and Nutrition Examination Surveys conducted between 1971 and 2002 for trends in self-reported intakes of energy, macronutrients, micronutrients, fruits and vegetables, and the energy density of foods, among U.S. non-Hispanic black (n = 7099) and white (n = 23,314) men and women aged 25–74 years. Logistic and linear regression methods were used to adjust for multiple covariates and survey design. Results Energy intake, amount of food, and carbohydrate energy increased, whereas percentage of energy from protein, fat, and saturated fat decreased over time in all race-gender groups (p <0.001). In whites and in black women energy-density increased (p <0.001) in parallel to increases in obesity prevalence. In all surveys, black men and women reported lower intakes of vegetables, potassium, and calcium (p <0.001) than their white counterparts. In men, the race differential in calcium intake increased across surveys (p = 0.004). Conclusions Dietary intake trends in blacks and whites from 1971–2002 were similar—suggesting that previously identified dietary risk factors that differentially affect black Americans have not improved in a relative sense. PMID:17383557

U.S. NO₂ trends (2005–2013): EPA air quality system (AQS) data versus improved observations from the Ozone Monitoring Instrument (OMI)

DOE PAGES

Lamsal, Lok N.; Duncan, Bryan N.; Yoshida, Yasuko; ...

2015-06-01

-simulated trends in VCDs strongly correlate with those estimated from surface concentrations (r = 0.83, N = 355). We then explore the observed correspondence of trends estimated from OMI and AQS data. We find a significant, but slightly weaker, correspondence (i.e., r = 0.68, N = 208) than predicted by the model and discuss some of the important factors affecting the relationship, including known problems (e.g., NO z interferents) associated with the AQS data. This significant correspondence gives confidence in trend and surface concentration estimates from OMI VCDs for locations, such as the majority of the U.S. and globe, that are not covered by surface monitoring networks. Using our improved trend model and our enhanced OMI data product, we find that both OMI and AQS data show substantial downward trends from 2005 to 2013, with an average reduction of 38% for each over the U.S. The annual reduction rates inferred from OMI and AQS measurements are larger (–4.8 ± 1.9%/yr, –3.7 ± 1.5%/yr) from 2005 to 2008 than 2010 to 2013 (–1.2 ± 1.2%/yr, –2.1 ± 1.4%/yr). We quantify NO₂ trends for major U.S. cities and power plants; the latter suggest larger negative trend (–4.0 ± 1.5%/yr) between 2005 and 2008 and smaller or insignificant changes (–0.5 ± 1.2%/yr) during 2010-2013.« less

U.S. NO₂ trends (2005–2013): EPA air quality system (AQS) data versus improved observations from the Ozone Monitoring Instrument (OMI)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lamsal, Lok N.; Duncan, Bryan N.; Yoshida, Yasuko

-simulated trends in VCDs strongly correlate with those estimated from surface concentrations (r = 0.83, N = 355). We then explore the observed correspondence of trends estimated from OMI and AQS data. We find a significant, but slightly weaker, correspondence (i.e., r = 0.68, N = 208) than predicted by the model and discuss some of the important factors affecting the relationship, including known problems (e.g., NO z interferents) associated with the AQS data. This significant correspondence gives confidence in trend and surface concentration estimates from OMI VCDs for locations, such as the majority of the U.S. and globe, that are not covered by surface monitoring networks. Using our improved trend model and our enhanced OMI data product, we find that both OMI and AQS data show substantial downward trends from 2005 to 2013, with an average reduction of 38% for each over the U.S. The annual reduction rates inferred from OMI and AQS measurements are larger (–4.8 ± 1.9%/yr, –3.7 ± 1.5%/yr) from 2005 to 2008 than 2010 to 2013 (–1.2 ± 1.2%/yr, –2.1 ± 1.4%/yr). We quantify NO₂ trends for major U.S. cities and power plants; the latter suggest larger negative trend (–4.0 ± 1.5%/yr) between 2005 and 2008 and smaller or insignificant changes (–0.5 ± 1.2%/yr) during 2010-2013.« less

Hunting and fishing trends in the U.S.

Treesearch

J. John Charbonneau; James R. Lyons

1980-01-01

Trends in hunting and fishing participation are evaluated on the basis of responses to a telephone survey of the U.S. population conducted as a part of the 1975 National Hunting and Fishing Survey. Probability of participation in hunting and fishing is a function of the respondent's age, sex, income, place of residence, and a number of supply characteristics. The...

Accelerometer profiles of physical activity and inactivity in normal weight, overweight, and obese U.S. men and women.

PubMed

Tudor-Locke, Catrine; Brashear, Meghan M; Johnson, William D; Katzmarzyk, Peter T

2010-08-03

The 2005-2006 National Health and Nutrition Examination Survey (NHANES) is used to describe an accelerometer-derived physical activity/inactivity profile in normal weight (BMI < 25 kg/m2), overweight (25 /= 30 kg/m2) U.S. adults. We computed physical activity volume indicators (activity counts/day, uncensored and censored steps/day), rate indicators (e.g., steps/minute), time indicators (employing NHANES activity counts/minute cut points to infer time in non-wear, sedentary, low, light, moderate, and vigorous intensities), the number of breaks in sedentary time (occasions when activity counts rose from < 100 activity/counts in one minute to >/= 100 activity counts in the subsequent minute), achievement of public health guidelines, and classification by step-defined physical activity levels. Data were examined for evidence of consistent and significant gradients across BMI-defined categories. In 2005-2006, U.S adults averaged 6,564 +/- SE 107 censored steps/day, and after considering non-wear time, they spent approximately 56.8% of the rest of the waking day in sedentary time, 23.7% in low intensity, 16.7% in light intensity, 2.6% in moderate intensity, and 0.2% in vigorous intensity. Overall, approximately 3.2% of U.S. adults achieved public health guidelines. The normal weight category took 7,190 +/- SE 157 steps/day, and spent 25.7 +/- 0.9 minutes/day in moderate intensity and 7.3 +/- 0.4 minutes/day in vigorous intensity physical activity. The corresponding numbers for the overweight category were 6,879 +/- 140 steps/day, 25.3 +/- 0.9 minutes/day, and 5.3 +/- 0.5 minutes/day and for the obese category 5,784 +/- 124 steps/day, 17.3 +/- 0.7 minutes/day and 3.2 +/- 0.4 minutes/day. Across BMI categories, increasing gradients and significant trends were apparent in males for sedentary time and decreasing gradients and significant trends were evident in time spent in light intensity, moderate intensity, and vigorous intensity. For

Centrality Dependence of the Charged-Particle Multiplicity Density at Midrapidity in Pb-Pb Collisions at √{sN N }=5.02 TeV

NASA Astrophysics Data System (ADS)

Adam, J.; Adamová, D.; Aggarwal, M. M.; Aglieri Rinella, G.; Agnello, M.; Agrawal, N.; Ahammed, Z.; Ahmad, S.; Ahn, S. U.; Aiola, S.; Akindinov, A.; Alam, S. N.; Aleksandrov, D.; Alessandro, B.; Alexandre, D.; Alfaro Molina, R.; Alici, A.; Alkin, A.; Almaraz, J. R. M.; Alme, J.; Alt, T.; Altinpinar, S.; Altsybeev, I.; Alves Garcia Prado, C.; Andrei, C.; Andronic, A.; Anguelov, V.; Antičić, T.; Antinori, F.; Antonioli, P.; Aphecetche, L.; Appelshäuser, H.; Arcelli, S.; Arnaldi, R.; Arnold, O. W.; Arsene, I. C.; Arslandok, M.; Audurier, B.; Augustinus, A.; Averbeck, R.; Azmi, M. D.; Badalà, A.; Baek, Y. W.; Bagnasco, S.; Bailhache, R.; Bala, R.; Balasubramanian, S.; Baldisseri, A.; Baral, R. C.; Barbano, A. M.; Barbera, R.; Barile, F.; Barnaföldi, G. G.; Barnby, L. S.; Barret, V.; Bartalini, P.; Barth, K.; Bartke, J.; Bartsch, E.; Basile, M.; Bastid, N.; Basu, S.; Bathen, B.; Batigne, G.; Batista Camejo, A.; Batyunya, B.; Batzing, P. C.; Bearden, I. G.; Beck, H.; Bedda, C.; Behera, N. K.; Belikov, I.; Bellini, F.; Bello Martinez, H.; Bellwied, R.; Belmont, R.; Belmont-Moreno, E.; Belyaev, V.; Benacek, P.; Bencedi, G.; Beole, S.; Berceanu, I.; Bercuci, A.; Berdnikov, Y.; Berenyi, D.; Bertens, R. A.; Berzano, D.; Betev, L.; Bhasin, A.; Bhat, I. R.; Bhati, A. K.; Bhattacharjee, B.; Bhom, J.; Bianchi, L.; Bianchi, N.; Bianchin, C.; Bielčík, J.; Bielčíková, J.; Bilandzic, A.; Biro, G.; Biswas, R.; Biswas, S.; Bjelogrlic, S.; Blair, J. T.; Blau, D.; Blume, C.; Bock, F.; Bogdanov, A.; Bøggild, H.; Boldizsár, L.; Bombara, M.; Book, J.; Borel, H.; Borissov, A.; Borri, M.; Bossú, F.; Botta, E.; Bourjau, C.; Braun-Munzinger, P.; Bregant, M.; Breitner, T.; Broker, T. A.; Browning, T. A.; Broz, M.; Brucken, E. J.; Bruna, E.; Bruno, G. E.; Budnikov, D.; Buesching, H.; Bufalino, S.; Buncic, P.; Busch, O.; Buthelezi, Z.; Butt, J. B.; Buxton, J. T.; Caffarri, D.; Cai, X.; Caines, H.; Calero Diaz, L.; Caliva, A.; Calvo Villar, E.; Camerini, P.; Carena, F.; Carena, W.; Carnesecchi, F.; Castillo Castellanos, J.; Castro, A. J.; Casula, E. A. R.; Ceballos Sanchez, C.; Cerello, P.; Cerkala, J.; Chang, B.; Chapeland, S.; Chartier, M.; Charvet, J. L.; Chattopadhyay, S.; Chattopadhyay, S.; Chauvin, A.; Chelnokov, V.; Cherney, M.; Cheshkov, C.; Cheynis, B.; Chibante Barroso, V.; Chinellato, D. D.; Cho, S.; Chochula, P.; Choi, K.; Chojnacki, M.; Choudhury, S.; Christakoglou, P.; Christensen, C. H.; Christiansen, P.; Chujo, T.; Chung, S. U.; Cicalo, C.; Cifarelli, L.; Cindolo, F.; Cleymans, J.; Colamaria, F.; Colella, D.; Collu, A.; Colocci, M.; Conesa Balbastre, G.; Conesa Del Valle, Z.; Connors, M. E.; Contreras, J. G.; Cormier, T. M.; Corrales Morales, Y.; Cortés Maldonado, I.; Cortese, P.; Cosentino, M. R.; Costa, F.; Crochet, P.; Cruz Albino, R.; Cuautle, E.; Cunqueiro, L.; Dahms, T.; Dainese, A.; Danisch, M. C.; Danu, A.; Das, D.; Das, I.; Das, S.; Dash, A.; Dash, S.; de, S.; de Caro, A.; de Cataldo, G.; de Conti, C.; de Cuveland, J.; de Falco, A.; de Gruttola, D.; De Marco, N.; de Pasquale, S.; Deisting, A.; Deloff, A.; Dénes, E.; Deplano, C.; Dhankher, P.; di Bari, D.; di Mauro, A.; di Nezza, P.; Diaz Corchero, M. A.; Dietel, T.; Dillenseger, P.; Divià, R.; Djuvsland, Ø.; Dobrin, A.; Domenicis Gimenez, D.; Dönigus, B.; Dordic, O.; Drozhzhova, T.; Dubey, A. K.; Dubla, A.; Ducroux, L.; Dupieux, P.; Ehlers, R. J.; Elia, D.; Endress, E.; Engel, H.; Epple, E.; Erazmus, B.; Erdemir, I.; Erhardt, F.; Espagnon, B.; Estienne, M.; Esumi, S.; Eum, J.; Evans, D.; Evdokimov, S.; Eyyubova, G.; Fabbietti, L.; Fabris, D.; Faivre, J.; Fantoni, A.; Fasel, M.; Feldkamp, L.; Feliciello, A.; Feofilov, G.; Ferencei, J.; Fernández Téllez, A.; Ferreiro, E. G.; Ferretti, A.; Festanti, A.; Feuillard, V. J. G.; Figiel, J.; Figueredo, M. A. S.; Filchagin, S.; Finogeev, D.; Fionda, F. M.; Fiore, E. M.; Fleck, M. G.; Floris, M.; Foertsch, S.; Foka, P.; Fokin, S.; Fragiacomo, E.; Francescon, A.; Frankenfeld, U.; Fronze, G. G.; Fuchs, U.; Furget, C.; Furs, A.; Fusco Girard, M.; Gaardhøje, J. J.; Gagliardi, M.; Gago, A. M.; Gallio, M.; Gangadharan, D. R.; Ganoti, P.; Gao, C.; Garabatos, C.; Garcia-Solis, E.; Gargiulo, C.; Gasik, P.; Gauger, E. F.; Germain, M.; Gheata, A.; Gheata, M.; Ghosh, P.; Ghosh, S. K.; Gianotti, P.; Giubellino, P.; Giubilato, P.; Gladysz-Dziadus, E.; Glässel, P.; Goméz Coral, D. M.; Gomez Ramirez, A.; Gonzalez, V.; González-Zamora, P.; Gorbunov, S.; Görlich, L.; Gotovac, S.; Grabski, V.; Grachov, O. A.; Graczykowski, L. K.; Graham, K. L.; Grelli, A.; Grigoras, A.; Grigoras, C.; Grigoriev, V.; Grigoryan, A.; Grigoryan, S.; Grinyov, B.; Grion, N.; Gronefeld, J. M.; Grosse-Oetringhaus, J. F.; Grossiord, J.-Y.; Grosso, R.; Guber, F.; Guernane, R.; Guerzoni, B.; Gulbrandsen, K.; Gunji, T.; Gupta, A.; Gupta, R.; Haake, R.; Haaland, Ø.; Hadjidakis, C.; Haiduc, M.; Hamagaki, H.; Hamar, G.; Hamon, J. C.; Harris, J. W.; Harton, A.; Hatzifotiadou, D.; Hayashi, S.; Heckel, S. T.; Helstrup, H.; Herghelegiu, A.; Herrera Corral, G.; Hess, B. A.; Hetland, K. F.; Hillemanns, H.; Hippolyte, B.; Horak, D.; Hosokawa, R.; Hristov, P.; Huang, M.; Humanic, T. J.; Hussain, N.; Hussain, T.; Hutter, D.; Hwang, D. S.; Ilkaev, R.; Inaba, M.; Incani, E.; Ippolitov, M.; Irfan, M.; Ivanov, M.; Ivanov, V.; Izucheev, V.; Jacazio, N.; Jacobs, P. M.; Jadhav, M. B.; Jadlovska, S.; Jadlovsky, J.; Jahnke, C.; Jakubowska, M. J.; Jang, H. J.; Janik, M. A.; Jayarathna, P. H. S. Y.; Jena, C.; Jena, S.; Jimenez Bustamante, R. T.; Jones, P. G.; Jusko, A.; Kalinak, P.; Kalweit, A.; Kamin, J.; Kang, J. H.; Kaplin, V.; Kar, S.; Karasu Uysal, A.; Karavichev, O.; Karavicheva, T.; Karayan, L.; Karpechev, E.; Kebschull, U.; Keidel, R.; Keijdener, D. L. D.; Keil, M.; Mohisin Khan, M.; Khan, P.; Khan, S. A.; Khanzadeev, A.; Kharlov, Y.; Kileng, B.; Kim, D. W.; Kim, D. J.; Kim, D.; Kim, H.; Kim, J. S.; Kim, M.; Kim, S.; Kim, T.; Kirsch, S.; Kisel, I.; Kiselev, S.; Kisiel, A.; Kiss, G.; Klay, J. L.; Klein, C.; Klein, J.; Klein-Bösing, C.; Klewin, S.; Kluge, A.; Knichel, M. L.; Knospe, A. G.; Kobdaj, C.; Kofarago, M.; Kollegger, T.; Kolojvari, A.; Kondratiev, V.; Kondratyeva, N.; Kondratyuk, E.; Konevskikh, A.; Kopcik, M.; Kostarakis, P.; Kour, M.; Kouzinopoulos, C.; Kovalenko, O.; Kovalenko, V.; Kowalski, M.; Koyithatta Meethaleveedu, G.; Králik, I.; Kravčáková, A.; Kretz, M.; Krivda, M.; Krizek, F.; Kryshen, E.; Krzewicki, M.; Kubera, A. M.; Kučera, V.; Kuhn, C.; Kuijer, P. G.; Kumar, A.; Kumar, J.; Kumar, L.; Kumar, S.; Kurashvili, P.; Kurepin, A.; Kurepin, A. B.; Kuryakin, A.; Kweon, M. J.; Kwon, Y.; La Pointe, S. L.; La Rocca, P.; Ladron de Guevara, P.; Lagana Fernandes, C.; Lakomov, I.; Langoy, R.; Lara, C.; Lardeux, A.; Lattuca, A.; Laudi, E.; Lea, R.; Leardini, L.; Lee, G. R.; Lee, S.; Lehas, F.; Lemmon, R. C.; Lenti, V.; Leogrande, E.; León Monzón, I.; León Vargas, H.; Leoncino, M.; Lévai, P.; Li, S.; Li, X.; Lien, J.; Lietava, R.; Lindal, S.; Lindenstruth, V.; Lippmann, C.; Lisa, M. A.; Ljunggren, H. M.; Lodato, D. F.; Loenne, P. I.; Loginov, V.; Loizides, C.; Lopez, X.; López Torres, E.; Lowe, A.; Luettig, P.; Lunardon, M.; Luparello, G.; Lutz, T. H.; Maevskaya, A.; Mager, M.; Mahajan, S.; Mahmood, S. M.; Maire, A.; Majka, R. D.; Malaev, M.; Maldonado Cervantes, I.; Malinina, L.; Mal'Kevich, D.; Malzacher, P.; Mamonov, A.; Manko, V.; Manso, F.; Manzari, V.; Marchisone, M.; Mareš, J.; Margagliotti, G. V.; Margotti, A.; Margutti, J.; Marín, A.; Markert, C.; Marquard, M.; Martin, N. A.; Martin Blanco, J.; Martinengo, P.; Martínez, M. I.; Martínez García, G.; Martinez Pedreira, M.; Mas, A.; Masciocchi, S.; Masera, M.; Masoni, A.; Massacrier, L.; Mastroserio, A.; Matyja, A.; Mayer, C.; Mazer, J.; Mazzoni, M. A.; McDonald, D.; Meddi, F.; Melikyan, Y.; Menchaca-Rocha, A.; Meninno, E.; Mercado Pérez, J.; Meres, M.; Miake, Y.; Mieskolainen, M. M.; Mikhaylov, K.; Milano, L.; Milosevic, J.; Minervini, L. M.; Mischke, A.; Mishra, A. N.; Miśkowiec, D.; Mitra, J.; Mitu, C. M.; Mohammadi, N.; Mohanty, B.; Molnar, L.; Montaño Zetina, L.; Montes, E.; Moreira de Godoy, D. A.; Moreno, L. A. P.; Moretto, S.; Morreale, A.; Morsch, A.; Muccifora, V.; Mudnic, E.; Mühlheim, D.; Muhuri, S.; Mukherjee, M.; Mulligan, J. D.; Munhoz, M. G.; Munzer, R. H.; Murakami, H.; Murray, S.; Musa, L.; Musinsky, J.; Naik, B.; Nair, R.; Nandi, B. K.; Nania, R.; Nappi, E.; Naru, M. U.; Natal da Luz, H.; Nattrass, C.; Navarro, S. R.; Nayak, K.; Nayak, R.; Nayak, T. K.; Nazarenko, S.; Nedosekin, A.; Nellen, L.; Ng, F.; Nicassio, M.; Niculescu, M.; Niedziela, J.; Nielsen, B. S.; Nikolaev, S.; Nikulin, S.; Nikulin, V.; Noferini, F.; Nomokonov, P.; Nooren, G.; Noris, J. C. C.; Norman, J.; Nyanin, A.; Nystrand, J.; Oeschler, H.; Oh, S.; Oh, S. K.; Ohlson, A.; Okatan, A.; Okubo, T.; Olah, L.; Oleniacz, J.; Oliveira da Silva, A. C.; Oliver, M. H.; Onderwaater, J.; Oppedisano, C.; Orava, R.; Ortiz Velasquez, A.; Oskarsson, A.; Otwinowski, J.; Oyama, K.; Ozdemir, M.; Pachmayer, Y.; Pagano, P.; Paić, G.; Pal, S. K.; Pan, J.; Pandey, A. K.; Papikyan, V.; Pappalardo, G. S.; Pareek, P.; Park, W. J.; Parmar, S.; Passfeld, A.; Paticchio, V.; Patra, R. N.; Paul, B.; Pei, H.; Peitzmann, T.; Pereira da Costa, H.; Peresunko, D.; Pérez Lara, C. E.; Perez Lezama, E.; Peskov, V.; Pestov, Y.; Petráček, V.; Petrov, V.; Petrovici, M.; Petta, C.; Piano, S.; Pikna, M.; Pillot, P.; Pimentel, L. O. D. L.; Pinazza, O.; Pinsky, L.; Piyarathna, D. B.; Płoskoń, M.; Planinic, M.; Pluta, J.; Pochybova, S.; Podesta-Lerma, P. L. M.; Poghosyan, M. G.; Polichtchouk, B.; Poljak, N.; Poonsawat, W.; Pop, A.; Porteboeuf-Houssais, S.; Porter, J.; Pospisil, J.; Prasad, S. K.; Preghenella, R.; Prino, F.; Pruneau, C. A.; Pshenichnov, I.; Puccio, M.; Puddu, G.; Pujahari, P.; Punin, V.; Putschke, J.; Qvigstad, H.; Rachevski, A.; Raha, S.; Rajput, S.; Rak, J.; Rakotozafindrabe, A.; Ramello, L.; Rami, F.; Raniwala, R.; Raniwala, S.; Räsänen, S. S.; Rascanu, B. T.; Rathee, D.; Read, K. F.; Redlich, K.; Reed, R. J.; Rehman, A.; Reichelt, P.; Reidt, F.; Ren, X.; Renfordt, R.; Reolon, A. R.; Reshetin, A.; Revol, J.-P.; Reygers, K.; Riabov, V.; Ricci, R. A.; Richert, T.; Richter, M.; Riedler, P.; Riegler, W.; Riggi, F.; Ristea, C.; Rocco, E.; Rodríguez Cahuantzi, M.; Rodriguez Manso, A.; Røed, K.; Rogochaya, E.; Rohr, D.; Röhrich, D.; Romita, R.; Ronchetti, F.; Ronflette, L.; Rosnet, P.; Rossi, A.; Roukoutakis, F.; Roy, A.; Roy, C.; Roy, P.; Rubio Montero, A. J.; Rui, R.; Russo, R.; Ryabinkin, E.; Ryabov, Y.; Rybicki, A.; Sadovsky, S.; Šafařík, K.; Sahlmuller, B.; Sahoo, P.; Sahoo, R.; Sahoo, S.; Sahu, P. K.; Saini, J.; Sakai, S.; Saleh, M. A.; Salzwedel, J.; Sambyal, S.; Samsonov, V.; Šándor, L.; Sandoval, A.; Sano, M.; Sarkar, D.; Sarma, P.; Scapparone, E.; Scarlassara, F.; Schiaua, C.; Schicker, R.; Schmidt, C.; Schmidt, H. R.; Schuchmann, S.; Schukraft, J.; Schulc, M.; Schuster, T.; Schutz, Y.; Schwarz, K.; Schweda, K.; Scioli, G.; Scomparin, E.; Scott, R.; Šefčík, M.; Seger, J. E.; Sekiguchi, Y.; Sekihata, D.; Selyuzhenkov, I.; Senosi, K.; Senyukov, S.; Serradilla, E.; Sevcenco, A.; Shabanov, A.; Shabetai, A.; Shadura, O.; Shahoyan, R.; Shangaraev, A.; Sharma, A.; Sharma, M.; Sharma, M.; Sharma, N.; Shigaki, K.; Shtejer, K.; Sibiriak, Y.; Siddhanta, S.; Sielewicz, K. M.; Siemiarczuk, T.; Silvermyr, D.; Silvestre, C.; Simatovic, G.; Simonetti, G.; Singaraju, R.; Singh, R.; Singha, S.; Singhal, V.; Sinha, B. C.; Sinha, T.; Sitar, B.; Sitta, M.; Skaali, T. B.; Slupecki, M.; Smirnov, N.; Snellings, R. J. M.; Snellman, T. W.; Søgaard, C.; Song, J.; Song, M.; Song, Z.; Soramel, F.; Sorensen, S.; de Souza, R. D.; Sozzi, F.; Spacek, M.; Spiriti, E.; Sputowska, I.; Spyropoulou-Stassinaki, M.; Stachel, J.; Stan, I.; Stankus, P.; Stefanek, G.; Stenlund, E.; Steyn, G.; Stiller, J. H.; Stocco, D.; Strmen, P.; Suaide, A. A. P.; Sugitate, T.; Suire, C.; Suleymanov, M.; Suljic, M.; Sultanov, R.; Šumbera, M.; Szabo, A.; Szanto de Toledo, A.; Szarka, I.; Szczepankiewicz, A.; Szymanski, M.; Tabassam, U.; Takahashi, J.; Tambave, G. J.; Tanaka, N.; Tangaro, M. A.; Tarhini, M.; Tariq, M.; Tarzila, M. G.; Tauro, A.; Tejeda Muñoz, G.; Telesca, A.; Terasaki, K.; Terrevoli, C.; Teyssier, B.; Thäder, J.; Thomas, D.; Tieulent, R.; Timmins, A. R.; Toia, A.; Trogolo, S.; Trombetta, G.; Trubnikov, V.; Trzaska, W. H.; Tsuji, T.; Tumkin, A.; Turrisi, R.; Tveter, T. S.; Ullaland, K.; Uras, A.; Usai, G. L.; Utrobicic, A.; Vajzer, M.; Vala, M.; Valencia Palomo, L.; Vallero, S.; van der Maarel, J.; van Hoorne, J. W.; van Leeuwen, M.; Vanat, T.; Vande Vyvre, P.; Varga, D.; Vargas, A.; Vargyas, M.; Varma, R.; Vasileiou, M.; Vasiliev, A.; Vauthier, A.; Vechernin, V.; Veen, A. M.; Veldhoen, M.; Velure, A.; Venaruzzo, M.; Vercellin, E.; Vergara Limón, S.; Vernet, R.; Verweij, M.; Vickovic, L.; Viesti, G.; Viinikainen, J.; Vilakazi, Z.; Villalobos Baillie, O.; Villatoro Tello, A.; Vinogradov, A.; Vinogradov, L.; Vinogradov, Y.; Virgili, T.; Vislavicius, V.; Viyogi, Y. P.; Vodopyanov, A.; Völkl, M. A.; Voloshin, K.; Voloshin, S. A.; Volpe, G.; von Haller, B.; Vorobyev, I.; Vranic, D.; Vrláková, J.; Vulpescu, B.; Wagner, B.; Wagner, J.; Wang, H.; Wang, M.; Watanabe, D.; Watanabe, Y.; Weber, M.; Weber, S. G.; Weiser, D. F.; Wessels, J. P.; Westerhoff, U.; Whitehead, A. M.; Wiechula, J.; Wikne, J.; Wilk, G.; Wilkinson, J.; Williams, M. C. S.; Windelband, B.; Winn, M.; Yang, H.; Yang, P.; Yano, S.; Yasar, C.; Yin, Z.; Yokoyama, H.; Yoo, I.-K.; Yoon, J. H.; Yurchenko, V.; Yushmanov, I.; Zaborowska, A.; Zaccolo, V.; Zaman, A.; Zampolli, C.; Zanoli, H. J. C.; Zaporozhets, S.; Zardoshti, N.; Zarochentsev, A.; Závada, P.; Zaviyalov, N.; Zbroszczyk, H.; Zgura, I. S.; Zhalov, M.; Zhang, H.; Zhang, X.; Zhang, Y.; Zhang, C.; Zhang, Z.; Zhao, C.; Zhigareva, N.; Zhou, D.; Zhou, Y.; Zhou, Z.; Zhu, H.; Zhu, J.; Zichichi, A.; Zimmermann, A.; Zimmermann, M. B.; Zinovjev, G.; Zyzak, M.; Alice Collaboration

2016-06-01

The pseudorapidity density of charged particles, d Nch/d η , at midrapidity in Pb-Pb collisions has been measured at a center-of-mass energy per nucleon pair of √{sN N}=5.02 TeV . For the 5% most central collisions, we measure a value of 1943 ±54 . The rise in d Nch/d η as a function of √{sN N} is steeper than that observed in proton-proton collisions and follows the trend established by measurements at lower energy. The increase of d Nch/d η as a function of the average number of participant nucleons, ⟨Npart⟩ , calculated in a Glauber model, is compared with the previous measurement at √{sN N}=2.76 TeV . A constant factor of about 1.2 describes the increase in d Nch/d η from √{sN N}=2.76 to 5.02 TeV for all centrality classes, within the measured range of 0%-80% centrality. The results are also compared to models based on different mechanisms for particle production in nuclear collisions.

Hardwood chip market--was 2006 a "normal" year?

Treesearch

Peter J. Ince

2007-01-01

In the context of other recent years, 2006 turned out to be a relatively "normal" year for the U.S. hardwood chip market in terms of factors that influence supply and demand; such as prevailing weather conditions, energy price trends, and pulp and paper production. Gulf Coast hurricanes and rising energy prices drove hardwood chip and pulpwood markets in 2005...

Premature mortality in the U.S.-- trends by race, ethnicity, age, and region

Cancer.gov

DCEG scientists are spearheading the Premature Mortality Project—an interdisciplinary, multi-institutional effort to characterize U.S. trends in premature mortality. In the process, the team has uncovered distinct mortality trends by race, ethnicity, age, and region, and provided crucial information about the ongoing,

Spatial correlation in precipitation trends in the Brazilian Amazon

NASA Astrophysics Data System (ADS)

Buarque, Diogo Costa; Clarke, Robin T.; Mendes, Carlos Andre Bulhoes

2010-06-01

A geostatistical analysis of variables derived from Amazon daily precipitation records (trends in annual precipitation totals, trends in annual maximum precipitation accumulated over 1-5 days, trend in length of dry spell, trend in number of wet days per year) gave results that are consistent with those previously reported. Averaged over the Brazilian Amazon region as a whole, trends in annual maximum precipitations were slightly negative, the trend in the length of dry spell was slightly positive, and the trend in the number of wet days in the year was slightly negative. For trends in annual maximum precipitation accumulated over 1-5 days, spatial correlation between trends was found to extend up to a distance equivalent to at least half a degree of latitude or longitude, with some evidence of anisotropic correlation. Time trends in annual precipitation were found to be spatially correlated up to at least ten degrees of separation, in both W-E and S-N directions. Anisotropic spatial correlation was strongly evident in time trends in length of dry spell with much stronger evidence of spatial correlation in the W-E direction, extending up to at least five degrees of separation, than in the S-N. Because the time trends analyzed are shown to be spatially correlated, it is argued that methods at present widely used to test the statistical significance of climate trends over time lead to erroneous conclusions if spatial correlation is ignored, because records from different sites are assumed to be statistically independent.

1.5-V-threshold-voltage Schottky barrier normally-off AlGaN/GaN high-electron-mobility transistors with f T/f max of 41/125 GHz

NASA Astrophysics Data System (ADS)

Hou, Bin; Ma, Xiaohua; Yang, Ling; Zhu, Jiejie; Zhu, Qing; Chen, Lixiang; Mi, Minhan; Zhang, Hengshuang; Zhang, Meng; Zhang, Peng; Zhou, Xiaowei; Hao, Yue

2017-07-01

In this paper, a normally-off AlGaN/GaN high-electron-mobility transistors (HEMT) fabricated using inductively coupled plasma (ICP) CF4 plasma recessing and an implantation technique is reported. A gate-to-channel distance of ˜10 nm and an equivalent negative fluorine sheet charge density of -1.21 × 1013 cm-2 extracted using a simple threshold voltage (V th) analytical model result in a high V th of 1.5 V, a peak transconductance of 356 mS/mm, and a subthreshold slope of 133 mV/decade. A small degradation of channel mobility leads to a high RF performance with f T/f max of 41/125 GHz, resulting in a record high f T × L g product of 10.66 GHz·µm among Schottky barrier AlGaN/GaN normally-off HEMTs with V th exceeding 1 V, to the best of our knowledge.

Localized N20 Component of Somatosensory Evoked Magnetic Fields in Frontoparietal Brain Tumor Patients Using Noise-Normalized Approaches.

PubMed

Elaina, Nor Safira; Malik, Aamir Saeed; Shams, Wafaa Khazaal; Badruddin, Nasreen; Abdullah, Jafri Malin; Reza, Mohammad Faruque

2018-06-01

To localize sensorimotor cortical activation in 10 patients with frontoparietal tumors using quantitative magnetoencephalography (MEG) with noise-normalized approaches. Somatosensory evoked magnetic fields (SEFs) were elicited in 10 patients with somatosensory tumors and in 10 control participants using electrical stimulation of the median nerve via the right and left wrists. We localized the N20m component of the SEFs using dynamic statistical parametric mapping (dSPM) and standardized low-resolution brain electromagnetic tomography (sLORETA) combined with 3D magnetic resonance imaging (MRI). The obtained coordinates were compared between groups. Finally, we statistically evaluated the N20m parameters across hemispheres using non-parametric statistical tests. The N20m sources were accurately localized to Brodmann area 3b in all members of the control group and in seven of the patients; however, the sources were shifted in three patients relative to locations outside the primary somatosensory cortex (SI). Compared with the affected (tumor) hemispheres in the patient group, N20m amplitudes and the strengths of the current sources were significantly lower in the unaffected hemispheres and in both hemispheres of the control group. These results were consistent for both dSPM and sLORETA approaches. Tumors in the sensorimotor cortex lead to cortical functional reorganization and an increase in N20m amplitude and current-source strengths. Noise-normalized approaches for MEG analysis that are integrated with MRI show accurate and reliable localization of sensorimotor function.

pGenN, a gene normalization tool for plant genes and proteins in scientific literature.

PubMed

Ding, Ruoyao; Arighi, Cecilia N; Lee, Jung-Youn; Wu, Cathy H; Vijay-Shanker, K

2015-01-01

Automatically detecting gene/protein names in the literature and connecting them to databases records, also known as gene normalization, provides a means to structure the information buried in free-text literature. Gene normalization is critical for improving the coverage of annotation in the databases, and is an essential component of many text mining systems and database curation pipelines. In this manuscript, we describe a gene normalization system specifically tailored for plant species, called pGenN (pivot-based Gene Normalization). The system consists of three steps: dictionary-based gene mention detection, species assignment, and intra species normalization. We have developed new heuristics to improve each of these phases. We evaluated the performance of pGenN on an in-house expertly annotated corpus consisting of 104 plant relevant abstracts. Our system achieved an F-value of 88.9% (Precision 90.9% and Recall 87.2%) on this corpus, outperforming state-of-art systems presented in BioCreative III. We have processed over 440,000 plant-related Medline abstracts using pGenN. The gene normalization results are stored in a local database for direct query from the pGenN web interface (proteininformationresource.org/pgenn/). The annotated literature corpus is also publicly available through the PIR text mining portal (proteininformationresource.org/iprolink/).

Warming Trends and Bleaching Stress of the World’s Coral Reefs 1985-2012

NASA Astrophysics Data System (ADS)

Heron, Scott F.; Maynard, Jeffrey A.; van Hooidonk, Ruben; Eakin, C. Mark

2016-12-01

Coral reefs across the world’s oceans are in the midst of the longest bleaching event on record (from 2014 to at least 2016). As many of the world’s reefs are remote, there is limited information on how past thermal conditions have influenced reef composition and current stress responses. Using satellite temperature data for 1985-2012, the analysis we present is the first to quantify, for global reef locations, spatial variations in warming trends, thermal stress events and temperature variability at reef-scale (~4 km). Among over 60,000 reef pixels globally, 97% show positive SST trends during the study period with 60% warming significantly. Annual trends exceeded summertime trends at most locations. This indicates that the period of summer-like temperatures has become longer through the record, with a corresponding shortening of the ‘winter’ reprieve from warm temperatures. The frequency of bleaching-level thermal stress increased three-fold between 1985-91 and 2006-12 - a trend climate model projections suggest will continue. The thermal history data products developed enable needed studies relating thermal history to bleaching resistance and community composition. Such analyses can help identify reefs more resilient to thermal stress.

A spatiotemporal analysis of U.S. station temperature trends over the last century

NASA Astrophysics Data System (ADS)

Capparelli, V.; Franzke, C.; Vecchio, A.; Freeman, M. P.; Watkins, N. W.; Carbone, V.

2013-07-01

This study presents a nonlinear spatiotemporal analysis of 1167 station temperature records from the United States Historical Climatology Network covering the period from 1898 through 2008. We use the empirical mode decomposition method to extract the generally nonlinear trends of each station. The statistical significance of each trend is assessed against three null models of the background climate variability, represented by stochastic processes of increasing temporal correlation length. We find strong evidence that more than 50% of all stations experienced a significant trend over the last century with respect to all three null models. A spatiotemporal analysis reveals a significant cooling trend in the South-East and significant warming trends in the rest of the contiguous U.S. It also shows that the warming trend appears to have migrated equatorward. This shows the complex spatiotemporal evolution of climate change at local scales.

Trends in gel dosimetry: Preliminary bibliometric overview of active growth areas, research trends and hot topics from Gore’s 1984 paper onwards

NASA Astrophysics Data System (ADS)

Baldock, C.

2017-05-01

John Gore’s seminal 1984 paper on gel dosimetry spawned a vibrant research field ranging from fundamental science through to clinical applications. A preliminary bibliometric study was undertaken of the gel dosimetry family of publications inspired by, and resulting from, Gore’s original 1984 paper to determine active growth areas, research trends and hot topics from Gore’s paper up to and including 2016. Themes and trends of the gel dosimetry research field were bibliometrically explored by way of co-occurrence term maps using the titles and abstracts text corpora from the Web of Science database for all relevant papers from 1984 to 2016. Visualisation of similarities was used by way of the VOSviewer visualisation tool to generate cluster maps of gel dosimetry knowledge domains and the associated citation impact of topics within the domains. Heat maps were then generated to assist in the understanding of active growth areas, research trends, and emerging and hot topics in gel dosimetry.

Trends in Surface-Water Nitrate-N Concentrations and Loads from Predominantly-Forested Watersheds of the Chesapeake Bay Basin

NASA Astrophysics Data System (ADS)

Eshleman, K. N.

2011-12-01

Water quality monitoring data from streams and rivers provide the "gold standard" by which progress toward achieving real reductions in nutrient loadings to Chesapeake Bay must ultimately be assessed. The most recent trend results posted at the Chesapeake Bay Program (CBP) website reveal that a substantial percentage of tributaries are now showing long-term declines in flow-adjusted concentrations of nutrients and sediments: 22 sites showed statistically significant (p < 0.05) downward trends (1985-2010) in flow-adjusted concentrations, two sites showed upward trends, and eight sites showed no trend. Based on the data, the CBP has drawn the following conclusion: "At many monitored locations, long-term trends indicate that management actions, such as pollution controls for improved wastewater treatment plants and practices to reduce nutrients on farms and suburban lands, have reduced concentrations of nitrogen." But could this conclusion be pre-mature? I recently undertook a comparable analysis of long-term nitrate-N trends for a different group of watersheds (all located in the Chesapeake Bay watershed with long data records); this group includes nine watersheds that are predominantly (i.e., >75%) forested, plus five other Potomac River subwatersheds added for comparison. Based on comparable data and analytical methods to those used by CBP partners and USGS, 13 of the 14 sites-including both Potomac River stations (Chain Bridge at Washington DC and Hancock, Maryland)-showed statistically significant decreasing linear trends in annual flow-weighted nitrate-N concentration. Only one station-the heavily agricultural Upper Monocacy River-did not show a statistically significant (p < 0.05) trend. Five of the predominantly-forested watersheds also showed statistically significant decreasing trends in annual nitrate-N loads, and none of the stations showed a trend in annual runoff presumably due to high inter-annual hydroclimatological variability. While the largest

Synthesis and crystal structure of (S, S, S, S)-N, N′-bis[N-(P-toluenesulfonamido)-1,2-diphenylethyl]ethylenediamine

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, X.-G.; Zhang, T.; Hu, Y.-Y.

2013-12-15

(S, S, S, S)-N,N′-bis[N-(p-toluenesulfonamido)-1,2-diphenylethyl] ethylenediamine (C{sub 44}H{sub 46}N{sub 4}O{sub 4}S{sub 2}), has been synthesized and structurally characterized by elemental analysis, {sup 1}H-NMR, MS, IR and single-crystal X-ray diffraction. The title compound contains four chiral centers with C atoms in S configuration. Molecules are connected to one another by hydrogen bonds between sulfonamide nitrogen and sulfonyl oxygen to form chains alone a axis.

pGenN, a Gene Normalization Tool for Plant Genes and Proteins in Scientific Literature

PubMed Central

Ding, Ruoyao; Arighi, Cecilia N.; Lee, Jung-Youn; Wu, Cathy H.; Vijay-Shanker, K.

2015-01-01

Background Automatically detecting gene/protein names in the literature and connecting them to databases records, also known as gene normalization, provides a means to structure the information buried in free-text literature. Gene normalization is critical for improving the coverage of annotation in the databases, and is an essential component of many text mining systems and database curation pipelines. Methods In this manuscript, we describe a gene normalization system specifically tailored for plant species, called pGenN (pivot-based Gene Normalization). The system consists of three steps: dictionary-based gene mention detection, species assignment, and intra species normalization. We have developed new heuristics to improve each of these phases. Results We evaluated the performance of pGenN on an in-house expertly annotated corpus consisting of 104 plant relevant abstracts. Our system achieved an F-value of 88.9% (Precision 90.9% and Recall 87.2%) on this corpus, outperforming state-of-art systems presented in BioCreative III. We have processed over 440,000 plant-related Medline abstracts using pGenN. The gene normalization results are stored in a local database for direct query from the pGenN web interface (proteininformationresource.org/pgenn/). The annotated literature corpus is also publicly available through the PIR text mining portal (proteininformationresource.org/iprolink/). PMID:26258475

Why the stratospheric zonal and meridional wind changes trend in the mid -1990s?

NASA Astrophysics Data System (ADS)

Krizan, P.

2016-12-01

This poster tries to explain the reasons for trend change of the stratospheric zonal and meridional wind in the mid-1990s. In the areas of negative (positive) wind speed trend before 1995 the positive (negative) trend is observed after this point Similar change is observed also for total ozone where we observe negative trend before 1995 and positive one after. We use MERRA reanalysis data especially monthly mean of geopotential from January to March. We suppose the position and strength of polar vortex and Aleutian high plays here very important role..

Rationale, Procedures, and Response Rates for the 2015 Administration of NCI’s Health Information National Trends Survey: HINTS-FDA 2015

PubMed Central

BLAKE, KELLY D.; PORTNOY, DAVID B.; KAUFMAN, ANNETTE R.; LIN, CHUNG-TUNG JORDAN; LO, SERENA C.; BACKLUND, ERIC; CANTOR, DAVID; HICKS, LLOYD; LIN, AMY; CAPORASO, ANDREW; DAVIS, TERISA; MOSER, RICHARD P.; HESSE, BRADFORD W.

2016-01-01

The National Cancer Institute (NCI) developed the Health Information National Trends Survey (HINTS) to monitor population trends in cancer communication practices, information preferences, health risk behaviors, attitudes, and cancer knowledge. The U.S. Food and Drug Administration (FDA) recognized HINTS as a unique data resource for informing its health communication endeavors and partnered with NCI to field HINTS-FDA 2015. HINTS-FDA 2015 was a self-administered paper instrument sent by mail May 29 to September 8, 2015, using a random probability-based sample of U.S. postal addresses stratified by county-level smoking rates, with an oversampling of high and medium-high smoking strata to increase the yield of current smokers responding to the survey. The response rate for HINTS-FDA 2015 was 33% (N = 3,738). The yield of current smokers (n = 495) was lower than expected, but the sampling strategy achieved the goal of obtaining more former smokers (n = 1,132). Public-use HINTS-FDA 2015 data and supporting documentation have been available for download and secondary data analyses since June 2016 at http://hints.cancer.gov. NCI and FDA encourage the use of HINTS-FDA for health communication research and practice related to tobacco-related communications, public knowledge, and behaviors as well as beliefs and actions related to medical products and dietary supplements. PMID:27892827

Onset of normal and inverse homoclinic bifurcation in a double plasma system near a plasma fireball

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mitra, Vramori; Sarma, Bornali; Sarma, Arun

Plasma fireballs are generated due to a localized discharge and appear as a luminous glow with a sharp boundary, which suggests the presence of a localized electric field such as electrical sheath or double layer structure. The present work reports the observation of normal and inverse homoclinic bifurcation phenomena in plasma oscillations that are excited in the presence of fireball in a double plasma device. The controlling parameters for these observations are the ratio of target to source chamber (n{sub T}/n{sub S}) densities and applied electrode voltage. Homoclinic bifurcation is noticed in the plasma potential fluctuations as the system evolvesmore » from narrow to long time period oscillations and vice versa with the change of control parameter. The dynamical transition in plasma fireball is demonstrated by spectral analysis, recurrence quantification analysis (RQA), and statistical measures, viz., skewness and kurtosis. The increasing trend of normalized variance reflects that enhancing n{sub T}/n{sub S} induces irregularity in plasma dynamics. The exponential growth of the time period is strongly indicative of homoclinic bifurcation in the system. The gradual decrease of skewness and increase of kurtosis with the increase of n{sub T}/n{sub S} also reflect growing complexity in the system. The visual change of recurrence plot and gradual enhancement of RQA variables DET, L{sub max}, and ENT reflects the bifurcation behavior in the dynamics. The combination of RQA and spectral analysis is a clear evidence that homoclinic bifurcation occurs due to the presence of plasma fireball with different density ratios. However, inverse bifurcation takes place due to the change of fireball voltage. Some of the features observed in the experiment are consistent with a model that describes the dynamics of ionization instabilities.« less

Trend differences in men and women in rural and urban U.S. settings.

PubMed

Cepeda-Benito, A; Doogan, N J; Redner, R; Roberts, M E; Kurti, A N; Villanti, A C; Lopez, A A; Quisenberry, A J; Stanton, C A; Gaalema, D E; Keith, D R; Parker, M A; Higgins, S T

2018-04-05

Smoking prevalence is declining at a slower rate in rural than urban settings in the United States (U.S.), and known predictors of smoking do not readily account for this trend difference. Given that socioeconomic and psychosocial determinants of health disparities accumulate in rural settings and that life-course disadvantages are often greater in women than men, we examined whether smoking trends are different for rural and urban men and women. We used yearly cross-sectional data (n = 303,311) from the U.S. National Survey on Drug Use and Health (NSDUH) from 2007 through 2014 to compare cigarette smoking trends in men and women across rural and urban areas. Current smoking status was modelled using logistic regression controlling for confounding risk factors. Regression derived graphs predicting unadjusted prevalence estimates and 95% confidence bands revealed that whereas the smoking trends of rural men, urban men, and urban women significantly declined from 2007 to 2014, the trend for rural women was flat. Controlling for demographic, socioeconomic and psychosocial predictors of smoking did not explain rural women's significantly different trend from those of the other three groups. Rural women lag behind rural men, urban men and urban women in decreasing smoking, a health disparity finding that supports the need for tobacco control and regulatory policies and interventions that are more effective in reducing smoking among rural women. Copyright © 2018 Elsevier Inc. All rights reserved.

Trends in the quality of water in New Jersey streams, water years 1971–2011

USGS Publications Warehouse

Hickman, R. Edward; Hirsch, Robert M.

2017-02-27

In a study conducted by the U.S. Geological Survey in cooperation with the New Jersey Department of Environmental Protection and the Delaware River Basin Commission, trend tests were conducted on selected water-quality characteristics measured at stations on streams in New Jersey during selected periods over water years 1971‒2011. Tests were conducted on 3 nutrients (total nitrogen, filtered nitrate plus nitrite, and total phosphorus) at 28 water-quality stations. At 4 of these stations, tests were also conducted on 3 measures of major ions (specific conductance, filtered chloride, and total dissolved solids).Two methods were used to identify trends—Weighted Regressions on Time, Discharge, and Season (WRTDS) models and seasonal rank-sum tests. For this report, the use of WRTDS models included the use of the WRTDS Bootstrap Test (WBT). WRTDS models identified trends in flow-normalized annual concentrations and flow-normalized annual fluxes over water years 1980‒2011 and 2000‒11 for each nutrient, filtered chloride, and total dissolved solids. WRTDS models were developed for each nutrient at the 20 or 21 stations at which streamflow was measured or estimated. Trends in nutrient concentration were reported for these stations; trends in nutrient fluxes were reported only for 15–17 of these stations.The results of WRTDS models for water years 1980‒2011 identified more stations with downward trends in concentrations of either total nitrogen or total phosphorus than upward trends. For total nitrogen, there were downward trends at 9 stations and an upward trend at 1 station. For total phosphorus, there were downward trends at 8 stations and an upward trend at 1 station. For filtered nitrate plus nitrite, there were downward trends at 6 stations and upward trends at 6 stations. The result of the trend test in flux for a selected nutrient at a selected station (downward trend, no trend, or upward trend) usually matched the trend result in concentration

The spectral theorem for quaternionic unbounded normal operators based on the S-spectrum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alpay, Daniel, E-mail: dany@math.bgu.ac.il; Kimsey, David P., E-mail: dpkimsey@gmail.com; Colombo, Fabrizio, E-mail: fabrizio.colombo@polimi.it

In this paper we prove the spectral theorem for quaternionic unbounded normal operators using the notion of S-spectrum. The proof technique consists of first establishing a spectral theorem for quaternionic bounded normal operators and then using a transformation which maps a quaternionic unbounded normal operator to a quaternionic bounded normal operator. With this paper we complete the foundation of spectral analysis of quaternionic operators. The S-spectrum has been introduced to define the quaternionic functional calculus but it turns out to be the correct object also for the spectral theorem for quaternionic normal operators. The lack of a suitable notion ofmore » spectrum was a major obstruction to fully understand the spectral theorem for quaternionic normal operators. A prime motivation for studying the spectral theorem for quaternionic unbounded normal operators is given by the subclass of unbounded anti-self adjoint quaternionic operators which play a crucial role in the quaternionic quantum mechanics.« less

U.S. Coastal Flood Damage Reduction Projects: Federal Authorization and Investment Trends

NASA Astrophysics Data System (ADS)

Carter, N. T.

2015-12-01

The 2015 U.S. Environmental Protection Agency report Climate Change in the United States: Benefits of Global Action estimated the potential cumulative future economic impacts of storm surge and sea-level rise on U.S. coasts during this century at 5 trillion (2014 dollars) if no adaptation measures are implemented. These impacts drop to 0.8 trillion if investments are made in cost-effective adaptations and protections. Awareness of flood risk and its long-term fiscal impact historically has proven insufficient to motivate pre-disaster land use changes and investments in mitigation and protection. While many adaptations and protections fall largely under state and local authority, some stakeholders are interested in federal coastal flood protection projects, including projects by the U.S. Army Corps of Engineers. Since the 1950s, Congress has authorized the Corps to construct specific coastal projects. The broad vision, strategy, and priorities for the federal role in coastal flood damage reduction projects nonetheless remain ill-defined. This research analyzes (1) the authorization and appropriations trends for Corps coastal storm damage reduction projects, and (2) how Corps feasibility studies account for and address coastal flood hazards. Identified trends include: emergency appropriations for storm-damaged areas outstrip annual investments in coastal flood projects; the rate at which projects are congressionally approved for construction outpaces the rate at which construction is funded; and how coastal protection projects are evaluated in Corps feasibility studies shows variation and change in agency practices. These trends have consequences; they affect public and local expectations when projects begin providing protection benefits, and may influence investments in other adaptation measures. These trends also raise questions for policymakers at all levels and for scientists and practitioners interested in coastal flood resilience.

Black-White Residential Segregation: The Views of Myrdal in the 1940s and Trends of the 1980s.

ERIC Educational Resources Information Center

Farley, Reynolds

1994-01-01

Traces the development of black-white residential segregation in U.S. cities, and applies the views of Gunnar Myrdal, expressed in the 1940s, to housing trends in the 1980s. While such segregation has decreased, blacks remain more segregated than two other large minority groups (i.e., Hispanics and Asians). Forces influencing residential…

Fretting properties of biodegradable Mg-Nd-Zn-Zr alloy in air and in Hank’s solution

NASA Astrophysics Data System (ADS)

Li, Wenting; Li, Nan; Zheng, Yufeng; Yuan, Guangyin

2016-11-01

Fretting is a significant cause for the failure of orthopedic implants. Currently, since magnesium and its alloys have been developed as promising biodegradable implant materials, the fretting behavior of the Mg alloys is of great research significance. In this study, a Mg-Nd-Zn-Zr alloy (hereafter, denoted as JDBM alloy) was selected as experimental material, and its fretting behaviors were evaluated under 5 N, 10 N and 20 N normal loads with a displacement of 200 μm under the frequency of 10 Hz at 37 °C in air and in Hank’s solution, respectively. The results indicated that while the friction coefficient decreased with the increment of the normal load, the wear volume of the alloy increased with the increment of the normal load both in air and in Hank’s solution. Both the friction coefficients and the wear volume of the fretting in Hank’s solution were much lower than those in air environment. The evolution trend of friction coefficients with time had different performance in air environment and the Hank’s solution group. Although oxidation occurred during the fretting tests in Hank’s solution, the damage of JDBM alloy was still reduced due to the lubrication effects of Hank’s solution. Moreover, the addition of Fetal bovine serum (FBS) could act as lubrication and result in the reduction of the fretting damage.

Asymptotic freedom in certain S O (N ) and S U (N ) models

NASA Astrophysics Data System (ADS)

Einhorn, Martin B.; Jones, D. R. Timothy

2017-09-01

We calculate the β -functions for S O (N ) and S U (N ) gauge theories coupled to adjoint and fundamental scalar representations, correcting longstanding, previous results. We explore the constraints on N resulting from requiring asymptotic freedom for all couplings. When we take into account the actual allowed behavior of the gauge coupling, the minimum value of N in both cases turns out to be larger than realized in earlier treatments. We also show that in the large N limit, both models have large regions of parameter space corresponding to total asymptotic freedom.

Recent Change of Vegetation Growth Trend in China

NASA Technical Reports Server (NTRS)

Peng, Shushi; Chen, Anping; Xu, Liang; Cao, Chunxiang; Fang, Jingyun; Myneni, Ranga B.; Pinzon, Jorge E.; Tucker, COmpton J.; Piao, Shilong

2011-01-01

Using satellite-derived normalized difference vegetation index (NDVI) data, several previous studies have indicated that vegetation growth significantly increased in most areas of China during the period 1982-99. In this letter, we extended the study period to 2010. We found that at the national scale the growing season (April-October) NDVI significantly increased by 0.0007/yr from 1982 to 2010, but the increasing trend in NDVI over the last decade decreased in comparison to that of the 1982-99 period. The trends in NDVI show significant seasonal and spatial variances. The increasing trend in April and May (AM) NDVI (0.0013/yr is larger than those in June, July and August (JJA) (0.0003/yr) and September and October (SO) (0.0008/yr). This relatively small increasing trend of JJA NDVI during 1982-2010 compared with that during 1982-99 (0.0012/yr) (Piao et al 2003 J. Geophys. Res.-Atmos. 108 4401) implies a change in the JJA vegetation growth trend, which significantly turned from increasing (0.0039/yr) to slightly decreasing (0:0002/yr) in 1988. Regarding the spatial pattern of changes in NDVI, the growing season NDVI increased (over 0.0020/yr) from 1982 to 2010 in southern China, while its change was close to zero in northern China, as a result of a significant changing trend reversal that occurred in the 1990s and early 2000s. In northern China, the growing season NDVI significantly increased before the 1990s as a result of warming and enhanced precipitation, but decreased after the 1990s due to drought stress strengthened by warming and reduced precipitation. Our results also show that the responses of vegetation growth to climate change vary across different seasons and ecosystems.

Genomic signature analysis of the recently emerged highly pathogenic A(H5N8) avian influenza virus: implying an evolutionary trend for bird-to-human transmission.

PubMed

Xu, Wei; Dai, Yanyan; Hua, Chen; Wang, Qian; Zou, Peng; Deng, Qiwen; Jiang, Shibo; Lu, Lu

2017-12-01

In early 2014, a novel subclade (2.3.4.4) of the highly pathogenic avian influenza (HPAI) A(H5N8) virus caused the first outbreak in domestic ducks and migratory birds in South Korea. Since then, it has spread to 44 countries and regions. To date, no human infections with A(H5N8) virus have been reported, but the possibility cannot be excluded. By analyzing the genomic signatures of A(H5N8) strains, we found that among the 47 species-associated signature positions, three positions exhibited human-like signatures (HLS), including PA-404S, PB2-613I and PB2-702R and that mutation trend of host signatures of avian A(H5N8) is different before and after 2014. About 82% of A(H5N8) isolates collected after January of 2014 carried the 3 HLS (PA-404S/PB2-613I/PB2-702R) in combination, while none of isolates collected before 2014 had this combination. Furthermore, the HA protein had S137A and S227R substitutions in the receptor-binding site and A160T in the glycosylation site, potentially increasing viral ability to bind human-type receptors. Based on these findings, the newly emerged HPAI A(H5N8) isolates show an evolutionary trend toward gaining more HLS and, along with it, the potential for bird-to-human transmissibility. Therefore, more extensive surveillance of this rapidly spreading HPAI A(H5N8) and preparedness against its potential pandemic are urgently needed. Copyright © 2017. Published by Elsevier Masson SAS.

U.S. Population Mobility and Distribution--Charts on Recent Trends.

ERIC Educational Resources Information Center

[Beale, Calvin L.

A total of 19 charts, each with a brief narrative interpretation, present information on major features of population trends in the United States. Residents of 212 metropolitan areas (central cities with population of 50,000 or more) equalled 64 percent of the population of the U.S. in 1968. The distribution of the population differed greatly by…

Trends in mercury wet deposition and mercury air concentrations across the U.S. and Canada

USGS Publications Warehouse

Weiss-Penzias, Peter S.; Gay, David A.; Brigham, Mark E.; Parsons, Matthew T.; Gustin, Mae S.; ter Shure, Arnout

2016-01-01

This study examined the spatial and temporal trends of mercury (Hg) in wet deposition and air concentrations in the United States (U.S.) and Canada between 1997 and 2013. Data were obtained from the National Atmospheric Deposition Program (NADP) and Environment Canada monitoring networks, and other sources. Of the 19 sites with data records from 1997–2013, 53% had significant negative trends in Hg concentration in wet deposition, while no sites had significant positive trends, which is in general agreement with earlier studies that considered NADP data up until about 2010. However, for the time period 2007–2013 (71 sites), 17% and 13% of the sites had significant positive and negative trends, respectively, and for the time period 2008–2013 (81 sites) 30% and 6% of the sites had significant positive and negative trends, respectively. Non-significant positive tendencies were also widespread. Regional trend analyses revealed significant positive trends in Hg concentration in the Rocky Mountains, Plains, and Upper Midwest regions for the recent time periods in addition to significant positive trends in Hg deposition for the continent as a whole. Sulfate concentration trends in wet deposition were negative in all regions, suggesting a lower importance of local Hg sources. The trend in gaseous elemental Hg from short-term datasets merged as one continuous record was broadly consistent with trends in Hg concentration in wet deposition, with the early time period (1998–2007) producing a significantly negative trend (− 1.5 ± 0.2% year− 1) and the recent time period (2008–2013) displaying a flat slope (− 0.3 ± 0.1% year− 1, not significant). The observed shift to more positive or less negative trends in Hg wet deposition primarily seen in the Central-Western regions is consistent with the effects of rising Hg emissions from regions outside the U.S. and Canada and the influence of long-range transport in the free troposphere.

Auditory function in normal-hearing, noise-exposed human ears

PubMed Central

Stamper, Greta C.; Johnson, Tiffany A.

2014-01-01

Objectives To determine if supra-threshold measures of auditory function, such as distortion-product otoacoustic emissions (DPOAEs) and auditory brainstem responses (ABRs), are correlated with noise exposure history in normal-hearing human ears. Recent data from animal studies have revealed significant deafferentation of auditory nerve fibers following full recovery from temporary noise-induced hearing loss (NIHL). Furthermore, these data report smaller ABR wave I amplitudes in noise-exposed animal ears when compared to non-noise exposed control animals or pre-noise exposure amplitudes in the same animal. It is unknown if a similar phenomenon exists in the normal-hearing, noise-exposed human ear. Design Thirty normal-hearing human subjects with a range of noise exposure backgrounds (NEBs) participated in this study. NEB was quantified by the use of a noise exposure questionnaire that extensively queried loud sound exposure over the previous 12 months. DPOAEs were collected at three f2’s (1, 2, and 4 kHz) over a range of L2’s. DPOAE stimulus level began at 80 dB FPL (forward-pressure level) and decreased in 10 dB steps. Two-channel ABRs were collected in response to click stimuli and 4 kHz tone bursts; one channel utilized an ipsilateral mastoid electrode and the other an ipsilateral tympanic membrane (TM) electrode. ABR stimulus level began at 90 dB nHL and was decreased in 10 dB steps. Amplitudes of waves I and V of the ABR were analyzed. Results A statistically significant relationship between ABR wave I amplitude and NEB was found for clicked-evoked ABRs recorded at a stimulus level of 90 dB nHL using a mastoid recording electrode. For this condition, ABR wave I amplitudes decreased as a function of NEB. Similar systematic trends were present for ABRs collected in response to clicks and 4 kHz tone bursts at additional supra-threshold stimulation levels (≥ 70 dB nHL). The relationship weakened and disappeared with decreases in stimulation level (≤ 60 dB n

Trends and uncertainties in U.S. cloud cover from weather stations and satellite data

NASA Astrophysics Data System (ADS)

Free, M. P.; Sun, B.; Yoo, H. L.

2014-12-01

Cloud cover data from ground-based weather observers can be an important source of climate information, but the record of such observations in the U.S. is disrupted by the introduction of automated observing systems and other artificial shifts that interfere with our ability to assess changes in cloudiness at climate time scales. A new dataset using 54 National Weather Service (NWS) and 101 military stations that continued to make human-augmented cloud observations after the 1990s has been adjusted using statistical changepoint detection and visual scrutiny. The adjustments substantially reduce the trends in U.S. mean total cloud cover while increasing the agreement between the cloud cover time series and those of physically related climate variables such as diurnal temperature range and number of precipitation days. For 1949-2009, the adjusted time series give a trend in U.S. mean total cloud of 0.11 ± 0.22 %/decade for the military data, 0.55 ± 0.24 %/decade for the NWS data, and 0.31 ± 0.22 %/decade for the combined dataset. These trends are less than half those in the original data. For 1976-2004, the original data give a significant increase but the adjusted data show an insignificant trend of -0.17 (military stations) to 0.66 %/decade (NWS stations). The differences between the two sets of station data illustrate the uncertainties in the U.S. cloud cover record. We compare the adjusted station data to cloud cover time series extracted from several satellite datasets: ISCCP (International Satellite Cloud Climatology Project), PATMOS-x (AVHRR Pathfinder Atmospheres Extended) and CLARA-a1 (CM SAF cLoud Albedo and RAdiation), and the recently developed PATMOS-x diurnally corrected dataset. Like the station data, satellite cloud cover time series may contain inhomogeneities due to changes in the observing systems and problems with retrieval algorithms. Overall we find good agreement between interannual variability in most of the satellite data and that in our

Step buffer layer of Al0.25Ga0.75N/Al0.08Ga0.92N on P-InAlN gate normally-off high electron mobility transistors

NASA Astrophysics Data System (ADS)

Shrestha, Niraj M.; Li, Yiming; Chang, E. Y.

2016-07-01

Normally-off AlGaN/GaN high electron mobility transistors (HEMTs) are indispensable devices for power electronics as they can greatly simplify circuit designs in a cost-effective way. In this work, the electrical characteristics of p-type InAlN gate normally-off AlGaN/GaN HEMTs with a step buffer layer of Al0.25Ga0.75N/Al0.1Ga0.9N is studied numerically. Our device simulation shows that a p-InAlN gate with a step buffer layer allows the transistor to possess normally-off behavior with high drain current and high breakdown voltage simultaneously. The gate modulation by the p-InAlN gate and the induced holes appearing beneath the gate at the GaN/Al0.25Ga0.75N interface is because a hole appearing in the p-InAlN layer can effectively vary the threshold voltage positively. The estimated threshold voltage of the normally-off HEMTs explored is 2.5 V at a drain bias of 25 V, which is 220% higher than the conventional p-AlGaN normally-off AlGaN/GaN gate injection transistor (GIT). Concurrently, the maximum current density of the explored HEMT at a drain bias of 10 V slightly decreases by about 7% (from 240 to 223 mA mm-1). At a drain bias of 15 V, the current density reached 263 mA mm-1. The explored structure is promising owing to tunable positive threshold voltage and the maintenance of similar current density; notably, its breakdown voltage significantly increases by 36% (from 800 V, GIT, to 1086 V). The engineering findings of this study indicate that novel p-InAlN for both the gate and the step buffer layer can feature a high threshold voltage, large current density and high operating voltage for advanced AlGaN/GaN HEMT devices.

Warming Trends and Bleaching Stress of the World’s Coral Reefs 1985–2012

PubMed Central

Heron, Scott F.; Maynard, Jeffrey A.; van Hooidonk, Ruben; Eakin, C. Mark

2016-01-01

Coral reefs across the world’s oceans are in the midst of the longest bleaching event on record (from 2014 to at least 2016). As many of the world’s reefs are remote, there is limited information on how past thermal conditions have influenced reef composition and current stress responses. Using satellite temperature data for 1985–2012, the analysis we present is the first to quantify, for global reef locations, spatial variations in warming trends, thermal stress events and temperature variability at reef-scale (~4 km). Among over 60,000 reef pixels globally, 97% show positive SST trends during the study period with 60% warming significantly. Annual trends exceeded summertime trends at most locations. This indicates that the period of summer-like temperatures has become longer through the record, with a corresponding shortening of the ‘winter’ reprieve from warm temperatures. The frequency of bleaching-level thermal stress increased three-fold between 1985–91 and 2006–12 – a trend climate model projections suggest will continue. The thermal history data products developed enable needed studies relating thermal history to bleaching resistance and community composition. Such analyses can help identify reefs more resilient to thermal stress. PMID:27922080

Continental U.S. streamflow trends from 1940 to 2009 and their relationships with watershed spatial characteristics

NASA Astrophysics Data System (ADS)

Rice, Joshua S.; Emanuel, Ryan E.; Vose, James M.; Nelson, Stacy A. C.

2015-08-01

Changes in streamflow are an important area of ongoing research in the hydrologic sciences. To better understand spatial patterns in past changes in streamflow, we examined relationships between watershed-scale spatial characteristics and trends in streamflow. Trends in streamflow were identified by analyzing mean daily flow observations between 1940 and 2009 from 967 U.S. Geological Survey stream gages. Results indicated that streamflow across the continental U.S., as a whole, increased while becoming less extreme between 1940 and 2009. However, substantial departures from the continental U.S. (CONUS) scale pattern occurred at the regional scale, including increased annual maxima, decreased annual minima, overall drying trends, and changes in streamflow variability. A subset of watersheds belonging to a reference data set exhibited significantly smaller trend magnitudes than those observed in nonreference watersheds. Boosted regression tree models were applied to examine the influence of watershed characteristics on streamflow trend magnitudes at both the CONUS and regional scale. Geographic location was found to be of particular importance at the CONUS scale while local variability in hydroclimate and topography tended to have a strong influence on regional-scale patterns in streamflow trends. This methodology facilitates detailed, data-driven analyses of how the characteristics of individual watersheds interact with large-scale hydroclimate forces to influence how changes in streamflow manifest.

Normal Coagulation

DTIC Science & Technology

2014-09-04

LO TTIN G with vitamin K antagonist...confidential until formal publication.6 F CHAPTER 34 Normal Coagulation 531 SE C T IO N 7 B LEED IN G A N D C LO TTIN G Table 34-1 Procoagulant...formal publication.8 F CHAPTER 34 Normal Coagulation 533 SE C T IO N 7 B LEED IN G A N D C LO TTIN G Figure 34-4 Vitamin K–dependent com-

Women victims of intentional homicide in Italy: New insights comparing Italian trends to German and U.S. trends, 2008-2014.

PubMed

Terranova, Claudio; Zen, Margherita

2018-01-01

National statistics on female homicide could be a useful tool to evaluate the phenomenon and plan adequate strategies to prevent and reduce this crime. The aim of the study is to contribute to the analysis of intentional female homicides in Italy by comparing Italian trends to German and United States trends from 2008 to 2014. This is a population study based on data deriving primarily from national and European statistical institutes, from the U.S. Federal Bureau of Investigation's Uniform Crime Reporting and from the National Center for Health Statistics. Data were analyzed in relation to trends and age by Chi-square test, Student's t-test and linear regression. Results show that female homicides, unlike male homicides, remained stable in the three countries. Regression analysis showed a higher risk for female homicide in all age groups in the U.S. Middle-aged women result at higher risk, and the majority of murdered women are killed by people they know. These results confirm previous findings and suggest the need to focus also in Italy on preventive strategies to reduce those precipitating factors linked to violence and present in the course of a relationship or within the family. Copyright © 2017 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

U.S. Natural Gas Markets: Recent Trends and Prospects for the Future

EIA Publications

2001-01-01

The purpose of this study is to examine recent trends and prospects for the future of the U.S. natural gas market. Natural gas prices rose dramatically in 2000 and remained high through the first part of 2001, raising concerns about the future of natural gas prices and potential for natural gas to fuel the growth of the U.S. economy.

Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Performance Verification Report: METSAT (S/N) AMSU-A1 Receiver Assemblies P/N 1356429-1 S/N F06 and P/N 1356409-1 S/N F06

NASA Technical Reports Server (NTRS)

1999-01-01

This is the Performance Verification Report, METSAT (S/N 109) AMSU-A1 Receiver Assemblies, P/N 1356429-1 S/N F06 and P/N 1356409 S/N F06, for the Integrated Advanced Microwave Sounding Unit-A (AMSU-A).

Fretting properties of biodegradable Mg-Nd-Zn-Zr alloy in air and in Hank’s solution

PubMed Central

Li, Wenting; Li, Nan; Zheng, Yufeng; Yuan, Guangyin

2016-01-01

Fretting is a significant cause for the failure of orthopedic implants. Currently, since magnesium and its alloys have been developed as promising biodegradable implant materials, the fretting behavior of the Mg alloys is of great research significance. In this study, a Mg-Nd-Zn-Zr alloy (hereafter, denoted as JDBM alloy) was selected as experimental material, and its fretting behaviors were evaluated under 5 N, 10 N and 20 N normal loads with a displacement of 200 μm under the frequency of 10 Hz at 37 °C in air and in Hank’s solution, respectively. The results indicated that while the friction coefficient decreased with the increment of the normal load, the wear volume of the alloy increased with the increment of the normal load both in air and in Hank’s solution. Both the friction coefficients and the wear volume of the fretting in Hank’s solution were much lower than those in air environment. The evolution trend of friction coefficients with time had different performance in air environment and the Hank’s solution group. Although oxidation occurred during the fretting tests in Hank’s solution, the damage of JDBM alloy was still reduced due to the lubrication effects of Hank’s solution. Moreover, the addition of Fetal bovine serum (FBS) could act as lubrication and result in the reduction of the fretting damage. PMID:27812007

Trends in the Relationship Between Obesity and Disability, 1988-2012.

PubMed

Chang, Virginia W; Alley, Dawn E; Dowd, Jennifer Beam

2017-09-15

Rising obesity rates, coupled with population aging, have elicited serious concern over the impact of obesity on disability in later life. Prior work showed a significant increase in the association between obesity and disability from 1988 to 2004, calling attention to disability as a cost of longer lifetime exposure to obesity. It is not known whether this trend has continued. We examined functional impairment and impairment in activities of daily living (ADL) (defined as severe or moderate to severe) for adults aged 60 years or older (n = 16,770) over 3 time periods in the National Health and Nutrition Examination Survey. The relative odds of impairment for obese individuals versus normal-weight individuals significantly increased from period 1 (1988-1994) to period 2 (1999-2004) for all outcomes. In period 3 (2005-2012), this association remained stable for functional and severe ADL impairment and decreased for moderate-to-severe ADL impairment. The fraction of population disability attributable to obesity followed a similar trend. The trend of an increasing association between obesity and disability has leveled off in more recent years, and is even improving for some measures. These findings suggest that public health and policy concerns that obesity would continue to become more disabling over time have not been borne out. © The Author(s) 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Economic and policy issues of U.S. agricultural pesticide use trends.

PubMed

Osteen, Craig D; Fernandez-Cornejo, Jorge

2013-09-01

This paper discusses U.S. agricultural pesticide use trends from 1964 to 2010 based on estimates developed from USDA surveys, and the influence of economic factors, agricultural policy, and pesticide regulation on aggregate quantities and mix of pesticides used. Synthetic organic pesticide use grew dramatically from the 1960s to the early 1980s, as farmers treated more and more acreage. Use then stabilized, with herbicides applied to about 95% of corn, cotton, and soybean acres, annually. Subsequently, major factors affecting trends were: (1) changes in crop acreage and other economic factors, (2) use of new pesticides that reduced per-acre application rates and/or met more rigorous health and environmental standards, and (3) adoption of genetically engineered insect-resistant and herbicide-tolerant crops. The use of pesticides and other control practices responded to economic factors such as input and output markets and agricultural policies. Changing societal values toward pesticide risks and benefits profoundly affected pesticide policy, influencing the pesticides available for use, but only indirectly affecting aggregate quantities used. While the current pesticide regulatory process might have economic inefficiencies, it might be consistent with policy preferences held by much of the public-to reduce pesticide hazards rather than minimize regulatory costs. Published 2013. This article is a U.S. Government work and is in the public domain in the USA.

Underweight and overweight among children and adolescents in Tuscany (Italy). Prevalence and short-term trends.

PubMed

Lazzeri, G; Rossi, S; Pammolli, A; Pilato, V; Pozzi, T; Giacchi, M V

2008-03-01

The recent increase in both childhood obesity and adolescent anorexia nervosa in developed countries has underlined the important consequences that these trends may have on public health, as there is an increased risk that these conditions may become chronic diseases in adulthood. Therefore, it is necessary to monitor prevalence rates and trends in thinness and overweight (including obesity) among children and adolescents at different levels: international, national and sub-national. Since 2001/2002, a nutritional surveillance system has been implemented in the Tuscany Region to estimate the nutritional status and lifestyles of children and adolescents. The main objectives were to assess the prevalence of thinness, overweight and obesity among Tuscan children and adolescents and to provide baseline information on the prevalence of thinness, for the first time calculated according to the new international definitions, for geographical comparisons and descriptions of time trends. Independent cross-sectional sample surveys were conducted in 2002, 2004 and 2006 in Tuscany, North-Central Italy. Data were collected from stratified two-stage cluster samples of children aged 9 years (n = 3,048 in 2002 and n = 1,430 in 2006) and of adolescents aged 11-13-15 years (n = 1,066, n = 1185 and n = 1,160 in 2004 and n = 1,189, n = 1,211 and n = 1,178 in 2006, respectively). Weights and heights of primary school children were measured by means of standardized methods, while those of adolescents were self-reported. Decimal age was calculated from the date of birth to the date of measurement. Body Mass Index classes were calculated according to the International Obesity Task Force standards. Instead of the term underweight in children, we used the term thinness, which the World Health Organization uses to mean low Body Mass Index for age in adults and adolescents. According to Cole's recently published cut-offs for thinness, we divided our Body Mass Index values below 18.5 into three

Time trends and patterns of reported egg consumption in the U.S. by sociodemographic characteristics

USDA-ARS?s Scientific Manuscript database

Objectives: To 1) describe time trends of the percentage of individuals in the U.S that consume eggs, 2) describe time trends of the daily amount of eggs consumed per day, and 3) examine differences in the amount of eggs consumed per day; overall and by gender, age, income, education, race-ethnicit...

Entropy generation and momentum transfer in the superconductor-normal and normal-superconductor phase transformations and the consistency of the conventional theory of superconductivity

NASA Astrophysics Data System (ADS)

Hirsch, J. E.

2018-05-01

Since the discovery of the Meissner effect, the superconductor to normal (S-N) phase transition in the presence of a magnetic field is understood to be a first-order phase transformation that is reversible under ideal conditions and obeys the laws of thermodynamics. The reverse (N-S) transition is the Meissner effect. This implies in particular that the kinetic energy of the supercurrent is not dissipated as Joule heat in the process where the superconductor becomes normal and the supercurrent stops. In this paper, we analyze the entropy generation and the momentum transfer between the supercurrent and the body in the S-N transition and the N-S transition as described by the conventional theory of superconductivity. We find that it is not possible to explain the transition in a way that is consistent with the laws of thermodynamics unless the momentum transfer between the supercurrent and the body occurs with zero entropy generation, for which the conventional theory of superconductivity provides no mechanism. Instead, we point out that the alternative theory of hole superconductivity does not encounter such difficulties.

Is there any trend change in wind speed in the mid- 1990s in the stratosphere?

NASA Astrophysics Data System (ADS)

Krizan, Peter

2017-04-01

This poster tries to explain the reasons for trend change of the stratospheric wind speed in the mid-1990s. In the areas of negative (positive) wind speed trend before 1995 the positive (negative) trend is observed after this point Similar change is observed also for total ozone where we observe negative trend before 1995 and positive one after. We use MERRA reanalysis monthly means of the geopotential height from January to March. We suppose the position and strength of polar vortex and Aleutian high plays here very important role.

Normalized fluctuations, H2O vs n-hexane: Site-correlated percolation

NASA Astrophysics Data System (ADS)

Koga, Yoshikata; Westh, Peter; Sawamura, Seiji; Taniguchi, Yoshihiro

1996-08-01

Entropy, volume and the cross fluctuations were normalized to the average volume of a coarse grain with a fixed number of molecules, within which the local and instantaneous value of interest is evaluated. Comparisons were made between liquid H2O and n-hexane in the range from -10 °C to 120 °C and from 0.1 MPa to 500 MPa. The difference between H2O and n-hexane in temperature and pressure dependencies of these normalized fluctuations was explained in terms of the site-correlated percolation theory for H2O. In particular, the temperature increase was confirmed to reduce the hydrogen bond probability, while the pressure appeared to have little effect on the hydrogen bond probability. According to the Le Chatelier principle, however, the putative formation of ``ice-like'' patches at low temperatures due to the site-correlated percolation requirement is retarded by pressure increases. Thus, only in the limited region of low pressure (<300 MPa) and temperature (<60 °C), the fluctuating ice-like patches are considered to persist.

N-S crustal shear system in the Bundelkhand massif: A unique crustal evolution signature in the northern Indian peninsula

NASA Astrophysics Data System (ADS)

Singh, S. P.; Bhattacharya, A. R.

2017-12-01

The Bundelkhand massif, located in the northern part of the Indian shield, is a poly-deformed and poly-metamorphic terrain. This paper reports a new shear system developed throughout the massif in the form of N-S trending quartz veins that are sometimes quartzo-feldspathic and rarely granitic in composition. The veins are vertical and commonly occur in conjugate sets. This tectono-magmatic event appears to represent the youngest shear system of the massif as it cross-cuts all the earlier shear systems (E-W, NE-SE and NW-SE). Emplacement of this N-S vein system may have taken place due to extensional processes that developed some cracks along which siliceous magma was vertically emplaced. The complete absence of signature of the N-S event from the surrounding sedimentary cover of Vindhyan Supergroup, Bijawar and Gwalior Groups suggests that this shear system is pre-tectonic to the nearly E-W trending passive basins developed at the margins of the Bundelkhand craton. Further, several workers have considered the Bundelkhand massif as a part of the Aravalli craton. However, due to the absence of N-S, as well as the other (i.e., E-W, NW-SE and NW-SE), tectonic fabrics of the Bundelkhand massif in other cratons of the Peninsular India, and vice versa, makes the Bundelkhand block a separate and unique craton of its own and is not part of the Aravalli craton.

Trends in normalized difference vegetation index (NDVI) associated with urban development in northern West Siberia

NASA Astrophysics Data System (ADS)

Esau, Igor; Miles, Victoria V.; Davy, Richard; Miles, Martin W.; Kurchatova, Anna

2016-08-01

Exploration and exploitation of oil and gas reserves of northern West Siberia has promoted rapid industrialization and urban development in the region. This development leaves significant footprints on the sensitive northern environment, which is already stressed by the global warming. This study reports the region-wide changes in the vegetation cover as well as the corresponding changes in and around 28 selected urbanized areas. The study utilizes the normalized difference vegetation index (NDVI) from high-resolution (250 m) MODIS data acquired for summer months (June through August) over 15 years (2000-2014). The results reveal the increase of NDVI (or "greening") over the northern (tundra and tundra-forest) part of the region. Simultaneously, the southern, forested part shows the widespread decrease of NDVI (or "browning"). These region-wide patterns are, however, highly fragmented. The statistically significant NDVI trends occupy only a small fraction of the region. Urbanization destroys the vegetation cover within the developed areas and at about 5-10 km distance around them. The studied urbanized areas have the NDVI values by 15 to 45 % lower than the corresponding areas at 20-40 km distance. The largest NDVI reduction is typical for the newly developed areas, whereas the older areas show recovery of the vegetation cover. The study reveals a robust indication of the accelerated greening near the older urban areas. Many Siberian cities become greener even against the wider browning trends at their background. Literature discussion suggests that the observed urban greening could be associated not only with special tending of the within-city green areas but also with the urban heat islands and succession of more productive shrub and tree species growing on warmer sandy soils.

Investigating recent trends in the U.S. teen birth rate.

PubMed

Kearney, Melissa S; Levine, Phillip B

2015-05-01

We investigate trends in the U.S. rate of teen childbearing between 1981 and 2010, focusing specifically on the sizable decline since 1991. We focus on establishing the role of state-level demographic changes, economic conditions, and targeted policies in driving recent aggregate trends. We offer three main observations. First, the recent decline cannot be explained by the changing racial and ethnic composition of teens. Second, the only targeted policies that have had a statistically discernible impact on aggregate teen birth rates are declining welfare benefits and expanded access to family planning services through Medicaid, but these policies can account for only 12.6 percent of the observed decline since 1991. Third, higher unemployment rates lead to lower teen birth rates and can account for 16 percent of the decline in teen birth rates since the Great Recession began. Copyright © 2015 Elsevier B.V. All rights reserved.

Trends in Serial Measurements of Ultrasound Markers in Second and Third Trimester Down Syndrome Fetuses.

PubMed

Vos, F I; De Jong-Pleij, E A P; Bakker, M; Tromp, E; Bilardo, C M

2015-01-01

To evaluate trends of nasal bone length (NBL), prenasal thickness (PT), nuchal fold (NF), prenasal thickness to nasal bone length (PT-NBL) ratio, and prefrontal space ratio (PFSR), measured serially in second- and third-trimester Down syndrome (DS) fetuses. Prenatal databases were searched for cases of continuing DS pregnancies with serial measurements, taken at least two weeks apart. Trends were plotted on previously reported normal ranges. Serial measurements were available in 25 Down syndrome fetuses. Median gestational age (GA) was 25 weeks; average number of visits per case was 2.44, with a median interval of 39 days between investigations. In DS fetuses, NBL and PT showed fairly stable trends with gestation. PFSR, but especially NF, had a more unpredictable trend. The PT-NBL ratio was the most stable marker, remaining unchanged in 95% of cases. NBL, PT, and NF showed more deviance from the normal range with advancing gestation, but MoM values remained stable. All but two fetuses had ultrasound markers or structural anomalies, especially heart defects. The PT-NBL ratio is the most constant DS marker throughout gestation, following a predictable trend. © 2015 S. Karger AG, Basel.

Urine sodium excretion increased slightly among U.S. adults between 1988 and 2010.

PubMed

Pfeiffer, Christine M; Hughes, Jeffery P; Cogswell, Mary E; Burt, Vicki L; Lacher, David A; Lavoie, Donna J; Rabinowitz, Daniel J; Johnson, Clifford L; Pirkle, James L

2014-05-01

Little information is available on temporal trends in sodium intake in the U.S. population using urine sodium excretion as a biomarker. Our aim was to assess 1988-2010 trends in estimated 24-h urine sodium (24hUNa) excretion among U.S. adults (age 20-59 y) participating in the cross-sectional NHANES. We used subsamples from a 1988-1994 convenience sample, a 2003-2006 one-third random sample, and a 2010 one-third random sample to comply with resource constraints. We estimated 24hUNa excretion from measured sodium concentrations in spot urine samples by use of calibration equations (for men and women) derived from the International Cooperative Study on Salt, Other Factors, and Blood Pressure study. Estimated 24hUNa excretion increased over the 20-y period [1988-1994, 2003-2006, and 2010; means ± SEMs (n): 3160 ± 38.4 mg/d (1249), 3290 ± 29.4 mg/d (1235), and 3290 ± 44.4 mg/d (525), respectively; P-trend = 0.022]. We observed significantly higher mean estimated 24hUNa excretion in each survey period (P < 0.001) for men compared with women (31-33%) and for persons with a higher body mass index (BMI; 32-35% for obese vs. normal weight) or blood pressure (17-26% for hypertensive vs. normal blood pressure). After adjusting for age, sex, and race-ethnicity, temporal trends in mean estimated 24hUNa excretion remained significant (P-trend = 0.004). We observed no temporal trends in mean estimated 24hUNa excretion among BMI subgroups, nor after adjusting for BMI. Although several limitations apply to this analysis (the use of a convenience sample in 1988-1994 and using estimated 24hUNa excretion as a biomarker of sodium intake), these first NHANES data suggest that mean estimated 24hUNa excretion increased slightly in U.S. adults over the past 2 decades, and this increase may be explained by a shift in the distribution of BMI.

Seasonal Trends in Stratospheric Water Vapor as Derived from SAGE II Data

NASA Technical Reports Server (NTRS)

Roell, Marilee M.; Fu, Rong

2008-01-01

Published analysis of HALOE and Boulder balloon measurements of water vapor have shown conflicting trends in stratospheric water vapor for the periods of 1981 through 2005. Analysis of the SAGE II monthly mean water vapor data filtered for large aerosol events for time periods from 1985-1991, 1995-1999, and 2000-2005 have shown a globally decreasing water vapor trend at 17.5km. Seasonal analysis for these three time periods show a decreasing trend in water vapor at 17.5km for the winter and spring seasons. The summer and autumn seasonal analysis show a decreasing trend from 1985-2005, however, there is a increasing trend in water vapor at 17.5km for these seasons during 1995-2005. Latitude vs height seasonal analysis show a decreasing trend in the lower stratosphere between 20S - 20N for the autumn season, while at the latitudes of 30-50S and 30-50N there is an increasing trend in water vapor at heights up to 15km for that season. Comparison with regions of monsoon activity (Asian and North American) show that the Asian monsoon region had some effect on the lower stratospheric moistening in 1995-1999, however, for the time period of 2000-2005, there was no change in the global trend analysis due to either monsoon region. This may be due to the limitations of the SAGE II data from 2000-2005.

Normal CAG and CCG repeats in the Huntington`s disease genes of Parkinson`s disease patients

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rubinsztein, D.C.; Leggo, J.; Barton, D.E.

1995-04-24

The clinical features of Parkinson`s disease, particularly rigidity and bradykinesia and occasionally tremor, are seen in juvenile-onset Huntington`s disease. Therefore, the CAG and CCG repeats in the Huntington`s disease gene were investigated in 45 Parkinson`s disease patients and compared to 40 control individuals. All of the Parkinson`s disease chromosomes fell within the normal size ranges. In addition, the distributions of the two repeats in the Parkinson`s disease patients did not differ significantly from those of the control population. Therefore, abnormalities of these trinucleotide repeats in the Huntington`s disease gene are not likely to contribute to the pathogenesis of Parkinson`s disease.more » 12 refs., 2 figs.« less

Land Use Dynamics Involving Forestland: Trends in the U.S. South

Treesearch

Ralph J. Alig; Michael R. Dicks; Robert J. Moulton

1998-01-01

Since 1952, U.S. timberland has decreased by about 20 million acres, with about one-quarter of the reduction in the South. Although some of the timberland has been converted to urban and developed uses, Larger amounts of land shifted uses between forest and agriculture because of changes in product markets and policy conditions. We summarize area trends for major land...

Spatio-temporal trends in monthly pan evaporation in Aguascalientes, Mexico

NASA Astrophysics Data System (ADS)

Ruiz-Alvarez, Osias; Singh, Vijay P.; Medina, Juan Enciso; Munster, Clyde; Kaiser, Ronald; Ontiveros-Capurata, Ronald Ernesto; Diaz-Garcia, Luis Antonio; dos Santos, Carlos Antonio Costa

2018-05-01

Emission of greenhouse gases is being alleged to be causing climate change in different regions of the world. The objective of this study was to analyze the spatio-temporal trends of monthly evaporation at 52 weather stations in the state of Aguascalientes (Mexico) which have hydrometeorological records of long periods. The autocorrelation was eliminated with an auto-regressive model, and the trend was determined using the Spearman (S) and Kendall (K) tests. The statistical significance of the trend was determined with the Spearman correlation coefficient (r s) and the Z statistic (the test statistic of the normal distribution) both indicated that that there were statistically significant trends in 107 time series, of these 88 series had negative trends and 19 series had positive trends. Negative trends were present in all months of the year, while positive trends occurred from February to May and from October to December only. The reduction of evaporation from - 4.10 to - 20.50 mm/month/year from June to September showed a hopeful future scenario for rainfed agriculture. Irrigated agriculture during dry months could have a reduction of irrigation requirements as a consequence of the reduction in reference and crop evapotranspiration. The evaporation increase during dry months could increase irrigation requirements and pumping, mainly in March, April, and November when there are trends with increases of about 26.90, 24.60, and 23.90 mm/month/year, respectively. The spatial variability of evaporation trend means that other effects of climate change could vary in different parts of the state. Results of this study will be useful for farmers and institutions in charge of the administration of water resources for developing adaptation and mitigation strategies to climate change.

Trends in purchases and intake of foods and beverages containing caloric and low-calorie sweeteners over the last decade in the U.S

PubMed Central

Piernas, Carmen; Ng, Shu Wen; Popkin, Barry

2013-01-01

Background Current food databases might not capture rapidly occurring changes in the food supply, such as the increased use of caloric (CS) and low-calorie sweeteners (LCS) in products. Objective We explored trends in purchases and intake of foods and beverages containing LCS, CS or both sweeteners over the last decade in the U.S., as well as household and SES predictors of these trends. Methods We analyzed household purchases from Homescan 2000–10 (n=140,352 households; 408,458 individuals); and dietary intake from NHANES 2003–10 (n=34,391 individuals). We estimated per-capita purchases and intake (g or mL/d) and percent of consumers of foods and beverages containing LCS, CS, or both LCS+CS. We estimated change in purchases associated with SES and household composition using random-effects longitudinal models. Results From 2000–10, percent of households purchasing CS products decreased, whereas for LCS and LCS+CS products increased among all types of households and particularly among those with children. African-American, Hispanic, and households with children had a higher % CS beverage purchases (+9%; +4%; +3% respectively, P<0.001) and lower % LCS beverage purchases (−12%; −5%; −2% respectively, P<0.001). Conclusions During a period of declining purchases and consumption of CS products, we have documented an increasing trend in products that contain LCS and a previously unexplored trend in products with both LCS and CS, especially important among households with children. PMID:23529974

Trends in U.S. Residential Natural Gas Consumption

EIA Publications

2010-01-01

This report presents an analysis of residential natural gas consumption trends in the United States through 2009 and analyzes consumption trends for the United States as a whole (1990 through 2009) and for each Census division (1998 through 2009).

Normal-Faulting in Madagascar: Another Round of Continental Rifting?

NASA Astrophysics Data System (ADS)

Wysession, M. E.; Pratt, M. J.; Tsiriandrimanana, R.; Andriampenomanana Ny Ony, F. S. T.; Nyblade, A.; Durrheim, R. J.; Tilmann, F. J.; Rumpker, G.; Rambolamanana, G.; Aleqabi, G. I.; Shore, P.

2017-12-01

Analyses of seismicity and seismic structure within Madagascar suggest the current occurrence of crustal extension, which may be related to continental rifting associated with a diffuse boundary between the Somalia and Lwandle tectonic plates. Madagascar has participated in two major rifting events as part of the break-up of Gondwana: the break-away of Greater India (Madagascar, India, the Seychelles) away from mainland Africa during the Jurassic and the break-away of India from Madagascar during the Cretaceous. Seismic activity and the structures obtained from it, using data from the 2-year (2011-2013) MACOMO project, suggest that this break-up may not be finished, and that continental rifts may be developing again. There are fairly high levels of intraplate seismicity within Madagascar: over 800 events located during the 22 months of the deployment. For comparison, a 2-year deployment of seismometers within the upper Midwest of the U.S. yielded just 12 intraplate earthquakes. While the Madagascar seismicity occurs across the island, it is strongly concentrated in the central region, where Cenozoic volcanism has occurred through the Holocene, and earthquakes align along N-S-trending lineations associated with N-S-trending pull-apart graben structures. The thickness of the crust is still >40 km in this region, but it is underlain by a large low-velocity structure within the lithosphere and asthenosphere that is observed in our studies of surface-wave, body-wave, and Pn-phase tomography. Normal faulting is not observed everywhere on the island, however; seismicity in the north is largely strike-slip, and seismicity in the south appears to be largely reverse faulting. Several studies have suggested that the diffuse boundary between the Somalia and Lwandle plates runs roughly E-W across Madagascar. Extensional faulting seems to predominate only within central Madagascar, likely associated with the current volcanic activity, which also appears to be associated with the

Bis(O-n-butyl dithio-carbonato-κS,S')bis-(pyridine-κN)manganese(II).

PubMed

Alam, Naveed; Ehsan, Muhammad Ali; Zeller, Matthias; Mazhar, Muhammad; Arifin, Zainudin

2011-08-01

The structure of the title manganese complex, [Mn(C(5)H(9)OS(2))(2)(C(5)H(5)N)(2)] or [Mn(S(2)CO-n-Bu)(2)(C(5)H(5)N)(2)], consists of discrete monomeric entities with Mn(2+) ions located on centres of inversion. The metal atom is coordinated by a six-coordinate trans-N(2)S(4) donor set with the pyridyl N atoms located in the apical positions. The observed slight deviations from octa-hedral geometry are caused by the bite angle of the bidentate κ(2)-S(2)CO-n-Bu ligands [69.48 (1)°]. The O(CH(2))(3)(CH(3)) chains of the O-n-butyl dithio-carbonate units are disordered over two sets of sites with an occupancy ratio of 0.589 (2):0.411 (2).

Detecting trends in raptor counts: power and type I error rates of various statistical tests

USGS Publications Warehouse

Hatfield, J.S.; Gould, W.R.; Hoover, B.A.; Fuller, M.R.; Lindquist, E.L.

1996-01-01

We conducted simulations that estimated power and type I error rates of statistical tests for detecting trends in raptor population count data collected from a single monitoring site. Results of the simulations were used to help analyze count data of bald eagles (Haliaeetus leucocephalus) from 7 national forests in Michigan, Minnesota, and Wisconsin during 1980-1989. Seven statistical tests were evaluated, including simple linear regression on the log scale and linear regression with a permutation test. Using 1,000 replications each, we simulated n = 10 and n = 50 years of count data and trends ranging from -5 to 5% change/year. We evaluated the tests at 3 critical levels (alpha = 0.01, 0.05, and 0.10) for both upper- and lower-tailed tests. Exponential count data were simulated by adding sampling error with a coefficient of variation of 40% from either a log-normal or autocorrelated log-normal distribution. Not surprisingly, tests performed with 50 years of data were much more powerful than tests with 10 years of data. Positive autocorrelation inflated alpha-levels upward from their nominal levels, making the tests less conservative and more likely to reject the null hypothesis of no trend. Of the tests studied, Cox and Stuart's test and Pollard's test clearly had lower power than the others. Surprisingly, the linear regression t-test, Collins' linear regression permutation test, and the nonparametric Lehmann's and Mann's tests all had similar power in our simulations. Analyses of the count data suggested that bald eagles had increasing trends on at least 2 of the 7 national forests during 1980-1989.

31 CFR 560.419 - U.S. employment of persons normally located in Iran.

Code of Federal Regulations, 2012 CFR

2012-07-01

... located in Iran. 560.419 Section 560.419 Money and Finance: Treasury Regulations Relating to Money and... REGULATIONS Interpretations § 560.419 U.S. employment of persons normally located in Iran. The prohibitions in § 560.201 make it unlawful to hire an Iranian national normally located in Iran to come to the United...

31 CFR 560.419 - U.S. employment of persons normally located in Iran.

Code of Federal Regulations, 2010 CFR

2010-07-01

... located in Iran. 560.419 Section 560.419 Money and Finance: Treasury Regulations Relating to Money and... REGULATIONS Interpretations § 560.419 U.S. employment of persons normally located in Iran. The prohibitions in § 560.201 make it unlawful to hire an Iranian national normally located in Iran to come to the United...

31 CFR 560.419 - U.S. employment of persons normally located in Iran.

Code of Federal Regulations, 2011 CFR

2011-07-01

... located in Iran. 560.419 Section 560.419 Money and Finance: Treasury Regulations Relating to Money and... REGULATIONS Interpretations § 560.419 U.S. employment of persons normally located in Iran. The prohibitions in § 560.201 make it unlawful to hire an Iranian national normally located in Iran to come to the United...

Masking of Lewis acidity trends in the solid-state structures of trichlorido- and tribromido(2,2':6',2''-terpyridine-κ(3)N,N',N'')gallium(III).

PubMed

Kazakov, Igor V; Bodensteiner, Michael; Timoshkin, Alexey Y

2014-03-01

The molecular structures of trichlorido(2,2':6',2''-terpyridine-κ(3)N,N',N'')gallium(III), [GaCl3(C15H11N3)], and tribromido(2,2':6',2''-terpyridine-κ(3)N,N',N'')gallium(III), [GaBr3(C15H11N3)], are isostructural, with the Ga(III) atom displaying an octahedral geometry. It is shown that the Ga-N distances in the two complexes are the same within experimental error, in contrast to expected bond lengthening in the bromide complex due to the lower Lewis acidity of GaBr3. Thus, masking of the Lewis acidity trends in the solid state is observed not only for complexes of group 13 metal halides with monodentate ligands but for complexes with the polydentate 2,2':6',2''-terpyridine donor as well.

Quantification of Local Warming Trend: A Remote Sensing-Based Approach

PubMed Central

Rahaman, Khan Rubayet; Hassan, Quazi K.

2017-01-01

Understanding the warming trends at local level is critical; and, the development of relevant adaptation and mitigation policies at those levels are quite challenging. Here, our overall goal was to generate local warming trend map at 1 km spatial resolution by using: (i) Moderate Resolution Imaging Spectroradiometer (MODIS)-based 8-day composite surface temperature data; (ii) weather station-based yearly average air temperature data; and (iii) air temperature normal (i.e., 30 year average) data over the Canadian province of Alberta during the period 1961–2010. Thus, we analysed the station-based air temperature data in generating relationships between air temperature normal and yearly average air temperature in order to facilitate the selection of year-specific MODIS-based surface temperature data. These MODIS data in conjunction with weather station-based air temperature normal data were then used to model local warming trends. We observed that almost 88% areas of the province experienced warming trends (i.e., up to 1.5°C). The study concluded that remote sensing technology could be useful for delineating generic trends associated with local warming. PMID:28072857

Recent trends in Cuba’s mining and petroleum industries

USGS Publications Warehouse

Wacaster, Susan; Baker, Michael S.; Soto-Viruet, Yadira; Textoris, Steven D.

2015-03-31

In response to recent diplomatic developments between Cuba and the United States, the National Minerals Information Center compiled available information on the mineral industries of Cuba. This fact sheet highlights a new map and table that identify mines, mineral processing facilities, and petroleum facilities as well as information on location, operational status, and ownership. It also addresses the current status of known mineral industry projects, historical developments, and trends of the Cuban economy with an emphasis on mineral industries, and the supply and demand for Cuba’s mineral resources.In 2013, Cuba was estimated to be among the world’s top ten producers of cobalt and nickel, which are the country’s leading exports. Cuba’s current crude oil and associated natural gas production from onshore and shallow water coastal reservoirs is approximately 50,000 barrels per day of liquids and about 20,000 barrels per day oil equivalent of natural gas. In 2013, the value of mining and quarrying activities accounted for 0.6 percent of Cuba’s gross domestic product (GDP), compared with 1.4 percent in 2000. The value of production from Cuba’s industrial manufacturing sector increased by 88 percent between 1993 and 2013, whereas the sector’s share in the GDP decreased by about 3 percent during the same time period reflecting economic growth in other sectors of the economy.

Quasi-normal modes from non-commutative matrix dynamics

NASA Astrophysics Data System (ADS)

Aprile, Francesco; Sanfilippo, Francesco

2017-09-01

We explore similarities between the process of relaxation in the BMN matrix model and the physics of black holes in AdS/CFT. Focusing on Dyson-fluid solutions of the matrix model, we perform numerical simulations of the real time dynamics of the system. By quenching the equilibrium distribution we study quasi-normal oscillations of scalar single trace observables, we isolate the lowest quasi-normal mode, and we determine its frequencies as function of the energy. Considering the BMN matrix model as a truncation of N=4 SYM, we also compute the frequencies of the quasi-normal modes of the dual scalar fields in the AdS5-Schwarzschild background. We compare the results, and we finda surprising similarity.

Stratospheric Ozone Trends and Variability as Seen by SCIAMACHY from 2002 to 2012

NASA Technical Reports Server (NTRS)

Gebhardt, C.; Rozanov, A.; Hommel, R.; Weber, M.; Bovensmann, H.; Burrows, J. P.; Degenstein, D.; Froidevaux, L.; Thompson, A. M.

2014-01-01

Vertical profiles of the rate of linear change (trend) in the altitude range 15-50 km are determined from decadal O3 time series obtained from SCIAMACHY/ENVISAT measurements in limb-viewing geometry. The trends are calculated by using a multivariate linear regression. Seasonal variations, the quasi-biennial oscillation, signatures of the solar cycle and the El Nino-Southern Oscillation are accounted for in the regression. The time range of trend calculation is August 2002-April 2012. A focus for analysis are the zonal bands of 20 deg N - 20 deg S (tropics), 60 - 50 deg N, and 50 - 60 deg S (midlatitudes). In the tropics, positive trends of up to 5% per decade between 20 and 30 km and negative trends of up to 10% per decade between 30 and 38 km are identified. Positive O3 trends of around 5% per decade are found in the upper stratosphere in the tropics and at midlatitudes. Comparisons between SCIAMACHY and EOS MLS show reasonable agreement both in the tropics and at midlatitudes for most altitudes. In the tropics, measurements from OSIRIS/Odin and SHADOZ are also analysed. These yield rates of linear change of O3 similar to those from SCIAMACHY. However, the trends from SCIAMACHY near 34 km in the tropics are larger than MLS and OSIRIS by a factor of around two.

The normal-weight type 2 diabetes phenotype revisited.

PubMed

Hermans, Michel P; Amoussou-Guenou, K Daniel; Bouenizabila, Evariste; Sadikot, Shaukat S; Ahn, Sylvie A; Rousseau, Michel F

2016-01-01

Type 2 diabetes (T2DM) is associated with obesity, insulin resistance and the metabolic syndrome (MetS). In non-diabetic populations, features of metabolic obesity (MO) are observed in a minority of normal-weight (NW) subjects. The cardiometabolic status of metabolically obese but normal-weight (MONW) individuals has not yet been phenotyped in T2DM. Prevalence and features of MONW were analyzed in 1244 T2DM patients, in whom MONW was identified as a BMI <25.0 and a MetS score ≥3/5. Among NW (n=262; 21%), those without MetS (n=152; NW-MetS[-]) were compared to NW-MetS[+] (n=110; i.e. 42% of NW and 9% of all T2DM). There were no differences between groups in age; gender; diabetes duration; smoking; BP; and LDL-C. NW-MetS[+] had higher BMI; waist; fat mass; visceral fat; liver steatosis and HbA1c, and lower insulin sensitivity. Non-right-handedness was twice-higher (18%) in NW-MetS[-]. NW-MetS[+] had higher apoB100 and triglycerides, and lower HDL-C and LDL size. Macroangiopathy was present in 39% of NW-MetS[+] vs. 22% of NW-MetS[-], as coronary (23% vs. 14%) or peripheral artery disease (14% vs. 5%) and TIA/stroke (15% vs. 7%). Microangiopathy was present in 54% of NW-MetS[+] vs. 32% of NW-MetS[-], as retinopathy (25% vs. 13%); neuropathy (29% vs. 18%); and albuminuria (39% vs. 20%). MONW among T2DM represents a significant minority (about 1 in 10). Their cardiometabolic phenotype deserves attention due to multiple comorbidities, including a twice-higher prevalence of micro-/macrovascular damage in patients wrongly perceived at lower risk due to normal BMI. Unexpectedly, non-right-handedness was over-represented among metabolically healthy patients. Copyright © 2016 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Cortical Thinning in Network-Associated Regions in Cognitively Normal and Below-Normal Range Schizophrenia

PubMed Central

Pinnock, Farena; Parlar, Melissa; Hawco, Colin; Hanford, Lindsay; Hall, Geoffrey B.

2017-01-01

This study assessed whether cortical thickness across the brain and regionally in terms of the default mode, salience, and central executive networks differentiates schizophrenia patients and healthy controls with normal range or below-normal range cognitive performance. Cognitive normality was defined using the MATRICS Consensus Cognitive Battery (MCCB) composite score (T = 50 ± 10) and structural magnetic resonance imaging was used to generate cortical thickness data. Whole brain analysis revealed that cognitively normal range controls (n = 39) had greater cortical thickness than both cognitively normal (n = 17) and below-normal range (n = 49) patients. Cognitively normal controls also demonstrated greater thickness than patients in regions associated with the default mode and salience, but not central executive networks. No differences on any thickness measure were found between cognitively normal range and below-normal range controls (n = 24) or between cognitively normal and below-normal range patients. In addition, structural covariance between network regions was high and similar across subgroups. Positive and negative symptom severity did not correlate with thickness values. Cortical thinning across the brain and regionally in relation to the default and salience networks may index shared aspects of the psychotic psychopathology that defines schizophrenia with no relation to cognitive impairment. PMID:28348889

77 FR 58149 - Recent Trends in U.S. Services Trade, 2013 Annual Report

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-19

... INTERNATIONAL TRADE COMMISSION [Investigation No. 332-345] Recent Trends in U.S. Services Trade, 2013 Annual Report AGENCY: United States International Trade Commission. ACTION: Schedule for 2013... offices are located in the United States International Trade Commission Building, 500 E Street SW...

Static and kinetic friction of granite at high normal stress

USGS Publications Warehouse

Byerlee, J.D.

1970-01-01

Frictional sliding on ground surfaces of granite, angle of sliding planes 30?? and 45??, was investigated as a function of confining pressure. Over the normal stress range of 2-12 kb, the static frictional shear stress ??s follows the relationship ??s = 0??5 + 0?? ??n and the kinetic frictional shear stress ??k was calculated to be ??k = 0??25 + 0??47 ??n. ?? 1970.

Accurate characterization and understanding of interface trap density trends between atomic layer deposited dielectrics and AlGaN/GaN with bonding constraint theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ramanan, Narayanan; Lee, Bongmook; Misra, Veena, E-mail: vmisra@ncsu.edu

2015-06-15

Many dielectrics have been proposed for the gate stack or passivation of AlGaN/GaN based metal oxide semiconductor heterojunction field effect transistors, to reduce gate leakage and current collapse, both for power and RF applications. Atomic Layer Deposition (ALD) is preferred for dielectric deposition as it provides uniform, conformal, and high quality films with precise monolayer control of film thickness. Identification of the optimum ALD dielectric for the gate stack or passivation requires a critical investigation of traps created at the dielectric/AlGaN interface. In this work, a pulsed-IV traps characterization method has been used for accurate characterization of interface traps withmore » a variety of ALD dielectrics. High-k dielectrics (HfO{sub 2}, HfAlO, and Al{sub 2}O{sub 3}) are found to host a high density of interface traps with AlGaN. In contrast, ALD SiO{sub 2} shows the lowest interface trap density (<2 × 10{sup 12 }cm{sup −2}) after annealing above 600 °C in N{sub 2} for 60 s. The trend in observed trap densities is subsequently explained with bonding constraint theory, which predicts a high density of interface traps due to a higher coordination state and bond strain in high-k dielectrics.« less

A Comparison of Observed and Simulated 1990 – 2010 U.S. Ozone Trends

EPA Science Inventory

In this study, we analyze ozone concentrations from long-term (1990 – 2010) WRF-CMAQ simulations driven by year specific meteorology and emissions. These simulations allow us to compare observed and simulated ozone trends in order to evaluate the model’s ability to pr...

Municipal distribution and trends in bladder cancer incidence in health area of León, Spain (1996-2010).

PubMed

del Canto, M; García-Martínez, L; Fernández-Villa, T; Molina, A J; Campanario, F; García-Sanz, M; López-Abente, G; Honrado, E; Martín-Sánchez, V

2015-01-01

Spain is a country where bladder cancer incidence and mortality rates are some of the highest in the world. The aim of this study is to know the incidence, trends and geographical distribution of bladder cancer in the health area of León. the new cases of bladder cancer (CIE-188) in patients residing in the health area of León and registered in the Hospital Tumor Registry of the Centro Asistencial Universitario in León (Spain) between 1996-2010 were included in this study. Triennial crude incidence and adjusted incidence rates to the worldwide and European population were calculated. Population data of the municipalities of Leon (Spain) were obtained from National Institute of Statistic of Spain (INE, Instituto Nacional de Estadística). Data were disaggregated by sex-groups and five-year age groups. Spatial distribution of smoothed municipal relative risks (RR) of bladder cancer was carried out using a Besag, York and Mollié model. Bayesian model were used to calculate the posterior probability (PP) of RR greater than one. 1.573 cases were included. Incidence rates standardized to European population increased among men from 20,8/100.000 (1996-98) to 33,1/100.000 (2006-2008) and among women these rates increased from 1,9/100.000 to 5,9/100.000 for the same period of time. No relevant differences were found in the municipal distribution of the incidences. bladder cancer incidence rates are high in the European context. Rising trends in incidence in both sexs, particularly in women are observed. Copyright © 2014 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

Proximity-induced superconductivity in all-silicon superconductor /normal-metal junctions

NASA Astrophysics Data System (ADS)

Chiodi, F.; Duvauchelle, J.-E.; Marcenat, C.; Débarre, D.; Lefloch, F.

2017-07-01

We have realized laser-doped all-silicon superconducting (S)/normal metal (N) bilayers of tunable thickness and dopant concentration. We observed a strong reduction of the bilayers' critical temperature when increasing the normal metal thickness, a signature of the highly transparent S/N interface associated to the epitaxial sharp laser doping profile. We extracted the interface resistance by fitting with the linearized Usadel equations, demonstrating a reduction of 1 order of magnitude from previous superconductor/doped Si interfaces. In this well-controlled crystalline system we exploited the low-resistance S/N interfaces to elaborate all-silicon lateral SNS junctions with long-range proximity effect. Their dc transport properties, such as the critical and retrapping currents, could be well understood in the diffusive regime. Furthermore, this work led to the estimation of important parameters in ultradoped superconducting Si, such as the Fermi velocity, the coherence length, or the electron-phonon coupling constant, fundamental to conceive all-silicon superconducting electronics.

A trend analysis of surgical operations under a global payment system in Tehran, Iran (2005–2015)

PubMed Central

Goudari, Faranak Behzadi; Rashidian, Arash; Arab, Mohammad; Mahmoudi, Mahmood

2018-01-01

Background Global payment system is a first example of per-case payment system that contains 60 commonly used surgical operations for which payment is based on the average cost per case in Iran. Objective The aim of the study was to determine the amount of reduction, increase or no change in the trend of global operations. Methods In this retrospective longitudinal study, data on the 60 primary global surgery codes was gathered from Tehran Health Insurance Organization within the ten-year period of 2005–2015 separately, for each month. Out of 60 surgery codes, only acceptable data for 46 codes were available based on the insurance documents sent by medical centers. A quantitative analysis of time series through Regression Analysis Model using STATA software v.11 was performed. Results Some global surgery codes had an upward trend and some were downwards. Of N Codes, N83, N20, N28, N63, and N93 had an upward trend (p<0.05) and N32, N43, N81 and N90 showed a significant downward trend (p<0.05). Similarly, all H Codes except for H18 had a significant upward trend (p<0.000). As such, K Codes including K45, K56 and K81 had an increasing movement. S Codes also experienced both increasing and decreasing trends. However, none of the O Codes changed according to time. Other global surgical codes like C61, E07, M51, L60, J98 (p<0.000), I84 (p<0.031) and I86 (p<0.000) shown upward and downward trends. Total global surgeries trend was significantly upwards (B=24.26109, p<0.000). Conclusion The varying trend of global surgeries can partly reflect the behavior of service providers in order to increase their profits and minimize their costs. PMID:29765576

Different evolutionary trends of swine H1N2 influenza viruses in Italy compared to European viruses

PubMed Central

2013-01-01

European H1N2 swine influenza viruses (EU H1N2SIVs) arose from multiple reassortment events among human H1N1, human H3N2, and avian influenza viruses. We investigated the evolutionary dynamics of 53 Italian H1N2 strains by comparing them with EU H1N2 SIVs. Hemagglutinin (HA) phylogeny revealed Italian strains fell into four groups: Group A and B (41 strains) had a human H1 similar to EU H1N2SIVs, which probably originated in 1986. However Group B (38 strains) formed a subgroup that had a two-amino acid deletion at positions 146/147 in HA. Group C (11 strains) contained an avian H1 that probably originated in 1996, and Group D (1 strain) had an H1 characteristic of the 2009 pandemic strain. Neuraminidase (NA) phylogeny suggested a series of genomic reassortments had occurred. Group A had an N2 that originated from human H3N2 in the late 1970s. Group B had different human N2 that most likely arose from a reassortment with the more recent human H3N2 virus, which probably occurred in 2000. Group C had an avian-like H1 combined with an N2 gene from one of EU H1N2SIVs, EU H3N2SIVs or Human H3N2. Group D was part of the EU H3N2SIVs clade. Although selection pressure for HA and NA was low, several positively selected sites were identified in both proteins, some of which were antigenic, suggesting selection influenced the evolution of SIV. The data highlight different evolutionary trends between European viruses and currently circulating Italian B strains and show the establishment of reassortant strains involving human viruses in Italian pigs. PMID:24289094

Different evolutionary trends of swine H1N2 influenza viruses in Italy compared to European viruses.

PubMed

Moreno, Ana; Gabanelli, Elena; Sozzi, Enrica; Lelli, Davide; Chiapponi, Chiara; Ciccozzi, Massimo; Zehender, Gianguglielmo; Cordioli, Paolo

2013-12-01

European H1N2 swine influenza viruses (EU H1N2SIVs) arose from multiple reassortment events among human H1N1, human H3N2, and avian influenza viruses. We investigated the evolutionary dynamics of 53 Italian H1N2 strains by comparing them with EU H1N2 SIVs. Hemagglutinin (HA) phylogeny revealed Italian strains fell into four groups: Group A and B (41 strains) had a human H1 similar to EU H1N2SIVs, which probably originated in 1986. However Group B (38 strains) formed a subgroup that had a two-amino acid deletion at positions 146/147 in HA. Group C (11 strains) contained an avian H1 that probably originated in 1996, and Group D (1 strain) had an H1 characteristic of the 2009 pandemic strain. Neuraminidase (NA) phylogeny suggested a series of genomic reassortments had occurred. Group A had an N2 that originated from human H3N2 in the late 1970s. Group B had different human N2 that most likely arose from a reassortment with the more recent human H3N2 virus, which probably occurred in 2000. Group C had an avian-like H1 combined with an N2 gene from one of EU H1N2SIVs, EU H3N2SIVs or Human H3N2. Group D was part of the EU H3N2SIVs clade. Although selection pressure for HA and NA was low, several positively selected sites were identified in both proteins, some of which were antigenic, suggesting selection influenced the evolution of SIV. The data highlight different evolutionary trends between European viruses and currently circulating Italian B strains and show the establishment of reassortant strains involving human viruses in Italian pigs.

Spin Transport in Electric-Barrier-Modulated Ferromagnetic/Normal/Ferromagnetic Monolayer Zigzag MoS2 Nanoribbon Junction

NASA Astrophysics Data System (ADS)

Xia, Y.-Y.; Yuan, R.-Y.; Yang, Q.-J.; Sun, Q.; Zheng, J.; Guo, Y.

In this paper, with the three-band tight-binding model and non-equilibrium Green’s function technique, we investigate spin transport in electric-barrier-modulated Ferromagnetic/Normal/Ferromagnetic (F/N/F) monolayer (ML) zigzag MoS2 nanoribbon junction. The results demonstrate that once the double electric barriers structure emerges, the oscillations of spin conductances become violent, especially for spin-down conductance, the numbers of resonant peaks increase obviously, thus we can obtain 100% spin polarization in the low energy region. It is also found that with the intensity of the exchange field enhancement, the resonant peaks of spin-up and spin-down conductances move in the opposite direction in a certain energy region. As a consequence, the spin-down conductance can be filtered out completely. The findings here indicate that the present structure may be considered as a good candidate for spin filter.

Spectral characteristics of normal and nutrient-deficient maize leaves

NASA Technical Reports Server (NTRS)

Al-Abbas, A. H.; Barr, R.; Hall, J. D.; Crane, F. L.; Baumgardner, M. F.

1972-01-01

Reflectance, transmittance and absorbance spectra of normal and six types of mineral-deficient (N,P,K,S,Mg and Ca) maize (Zea mays L.) leaves were analyzed at 30 selected wavelengths along the electromagnetic spectrum from 500 to 2600 nm. Chlorophyll content and percent leaf moisture were also determined. Leaf thermograms were obtained for normal, N- and S- deficient leaves. The results of the analysis of variance showed significant differences in reflectance, transmittance and absorbance in the visible wavelengths among leaf numbers 3, 4, and 5, among the seven nutrient treatments, and among the interactions of leaves and treatments. In the reflective infrared wavelengths only treatments produced significant differences. The chlorophyll content of leaves was reduced in all deficiencies in comparison to controls. Percent moisture was increased in S-, Mg- and N- deficiencies. Positive correlation (r = 0.707) between moisture content and percent absorption at both 1450 and 1930 nm were obtained. Polynomial regression analysis of leaf thickness and leaf moisture content showed that these two variables were significantly and directly related (r = 0.894).

Event activity dependence of Y(nS) production in $$\\sqrt{s_{NN}}$$=5.02 TeV pPb and $$\\sqrt{s}$$=2.76 TeV pp collisions

DOE PAGES

Chatrchyan, Serguei

2014-04-15

The production of Y(1S), Y(2S), and Y(3S) is investigated in pPb and pp collisions at centre-of-mass energies per nucleon pair of 5.02 TeV and 2.76 TeV, respectively. The datasets correspond to integrated luminosities of about 31 nb –1 (pPb) and 5.4 pb –1 (pp), collected in 2013 by the CMS experiment at the LHC. Upsilons that decay into muons are reconstructed within the rapidity interval (y CM) < 1.93 in the nucleon-nucleon centre-of-mass frame. Their production is studied as a function of two measures of event activity, namely the charged-particle multiplicity measured in the pseudorapidity interval |η| < 2.4, andmore » the sum of transverse energy deposited at forward pseudorapidity, 4.0 < |η|< 5.2. The Y cross sections normalized by their event activity integrated values, Y(nS)/, are found to rise with both measures of the event activity in pp and pPb. In both collision systems, the ratios of the excited to the ground state cross sections, Y(nS)/Y(1S), are found to decrease with the charged-particle multiplicity, while as a function of the transverse energy the variation is less pronounced. Lastly, the event activity integrated double ratios, [Y(nS)/Y(1S)] pPb / [Y(nS)/Y(1S)] pp, are also measured and found to be 0.83 +/- 0.05 (stat.) +/- 0.05 (syst.) and 0.71 +/- 0.08 (stat.) +/- 0.09 (syst.) for Y(2S) and Y(3S), respectively.« less

Status and Trends in the U.S. Voluntary Green Power Market (2014 Data)

DOE Office of Scientific and Technical Information (OSTI.GOV)

O'Shaughnessy, Eric; Heeter, Jenny; Liu, Chang

2015-10-16

NREL's annual report on green power markets summarizes status and trends in the voluntary demand for renewable energy. U.S. green power markets have become more complex over time as state-level policies have enabled more avenues for green power purchases. In recent years, community solar, community choice aggregation (CCA), and voluntary power purchase agreements (PPAs) have significantly increased the number of U.S. voluntary green power customers. The community solar model has grown rapidly with 90 projects in 25 states by 2015. Renewable energy sales in CCAs declined slightly in 2014 in response to less favorable economic conditions in Illinois. At themore » same time, several California CCAs continued to grow, and many more communities are planning to pursue green power through aggregation. Voluntary green power purchasing through bi-lateral PPAs took off in 2014 due to several large-scale agreements signed by information and communication technology firms. Traditional green power options, such as utility green pricing programs and voluntary RECs markets, also grew in 2014. Current trends suggest strong continued growth in U.S. voluntary green power markets.« less

Optimal allocation of trend following strategies

NASA Astrophysics Data System (ADS)

Grebenkov, Denis S.; Serror, Jeremy

2015-09-01

We consider a portfolio allocation problem for trend following (TF) strategies on multiple correlated assets. Under simplifying assumptions of a Gaussian market and linear TF strategies, we derive analytical formulas for the mean and variance of the portfolio return. We construct then the optimal portfolio that maximizes risk-adjusted return by accounting for inter-asset correlations. The dynamic allocation problem for n assets is shown to be equivalent to the classical static allocation problem for n2 virtual assets that include lead-lag corrections in positions of TF strategies. The respective roles of asset auto-correlations and inter-asset correlations are investigated in depth for the two-asset case and a sector model. In contrast to the principle of diversification suggesting to treat uncorrelated assets, we show that inter-asset correlations allow one to estimate apparent trends more reliably and to adjust the TF positions more efficiently. If properly accounted for, inter-asset correlations are not deteriorative but beneficial for portfolio management that can open new profit opportunities for trend followers. These concepts are illustrated using daily returns of three highly correlated futures markets: the E-mini S&P 500, Euro Stoxx 50 index, and the US 10-year T-note futures.

Examining Trends in Prediabetes and its Relationship with the Metabolic Syndrome in U.S. Adolescents, 1999–2014

PubMed Central

Lee, Arthur M.; Fermin, Cyrelle R.; Filipp, Stephanie L.; Gurka, Matthew J.; DeBoer, Mark D.

2017-01-01

Introduction Prediabetes is a reversible state of glycemic abnormalities that is frequently associated with obesity and the metabolic syndrome (MetS). There has been controversy over determining the most effective methods of determining prediabetes status in adolescents. We sought to investigate temporal trends in prediabetes prevalence among U.S. adolescents using two definitions and evaluate relationships with obesity and a MetS-severity score. Methods We evaluated data from 5418 non-Hispanic-white, non-Hispanic-black, and Hispanic adolescents aged 12–19 participating in the National Health and Nutrition Examination Survey 1999–2014 with complete data regarding MetS and hemoglobin A1c (HbA1c). Prediabetes status was defined by American Diabetes Association (ADA) criteria: fasting glucose 100–125 mg/dL or HbA1c 5.7%–6.4%. MetS severity was assessed with a MetS-severity Z-score. Results Prevalence of prediabetes as defined by HbA1c abnormalities significantly increased from 1999–2014, while prevalence of prediabetes as defined by fasting glucose abnormalities showed no significant temporal trend. There were variations in these trends across different racial/ethnic groups. MetS Z-score was overall more strongly correlated with HbA1c, fasting insulin, and the homeostasis-model-of-insulin-resistance than was BMI Z-score. These correlations were true in each racial/ethnic group with the exception that in non-Hispanic-white adolescents, in whom the MetS Z-score was not significantly correlated to HbA1c measurements. Conclusion We found conflicting findings of temporal trends of U.S. adolescent prediabetes prevalence based on the ADA’s prediabetes criteria. The increasing prevalence of prediabetes by HbA1c assessment is concerning and raises the urgency for increased awareness and appropriate measures of prediabetes status among physicians and patients. PMID:28070750

Multiyear applications of WRF/Chem over continental U.S.: Model evaluation, variation trend, and impacts of boundary conditions

NASA Astrophysics Data System (ADS)

Yahya, Khairunnisa; He, Jian; Zhang, Yang

2015-12-01

Multiyear applications of an online-coupled meteorology-chemistry model allow an assessment of the variation trends in simulated meteorology, air quality, and their interactions to changes in emissions and meteorology, as well as the impacts of initial and boundary conditions (ICONs/BCONs) on simulated aerosol-cloud-radiation interactions over a period of time. In this work, the Weather Research and Forecasting model with Chemistry version 3.4.1 (WRF/Chem v. 3.4.1) with the 2005 Carbon Bond mechanism coupled with the Volatility Basis Set module for secondary organic aerosol formation (WRF/Chem-CB05-VBS) is applied for multiple years (2001, 2006, and 2010) over continental U.S. This work also examines the changes in simulated air quality and meteorology due to changes in emissions and meteorology and the model's capability in reproducing the observed variation trends in species concentrations from 2001 to 2010. In addition, the impacts of the chemical ICONs/BCONs on model predictions are analyzed. ICONs/BCONs are downscaled from two global models, the modified Community Earth System Model/Community Atmosphere model version 5.1 (CESM/CAM v5.1) and the Monitoring Atmospheric Composition and Climate model (MACC). The evaluation of WRF/Chem-CB05-VBS simulations with the CESM ICONs/BCONs for 2001, 2006, and 2010 shows that temperature at 2 m (T2) is underpredicted for all three years likely due to inaccuracies in soil moisture and soil temperature, resulting in biases in surface relative humidity, wind speed, and precipitation. With the exception of cloud fraction, other aerosol-cloud variables including aerosol optical depth, cloud droplet number concentration, and cloud optical thickness are underpredicted for all three years, resulting in overpredictions of radiation variables. The model performs well for O3 and particulate matter with diameter less than or equal to 2.5 (PM2.5) for all three years comparable to other studies from literature. The model is able to

Factors associated with trends in infant and child mortality in developing countries during the 1990s.

PubMed Central

Rutstein, S. O.

2000-01-01

The 1990s have seen a remarkable decrease in mortality among infants and children in most developing countries. In some countries, particularly in sub-Saharan Africa, these declines in mortality among children have slowed and are now increasing again. Internationally comparable data derived from survey programmes, such as the Demographic and Health Survey (DHS) programme, are available both to document the changes that have occurred in mortality and to provide insight into some of the factors that may explain these trends in mortality. The factors found in repeated DHS programmes that explain these trends fall into five categories: fertility behaviour; nutritional status, breastfeeding, and infant feeding; the use of health services by mothers and for children; environmental health conditions; and socioeconomic status. Both simple analyses and multivariate analyses of changes in these factors between surveys indicate that all factors affected the mortality trends. However, to explain trends in mortality, the variables themselves had to have changed over time. During the 1990s fertility behaviour, breastfeeding, and infant feeding have changed less than other factors and so would seem to have played a smaller role in mortality trends. This study confirms that trends in mortality during the 1990s were related to more than just a handful of variables. It would, therefore, be a mistake to concentrate policy actions on one or a few of these while forsaking others. Countries with the largest decreases in mortality have had substantial improvements in most of the factors that might be used to explain these changes. In some countries mortality has risen. In part these increases can be explained by the factors included in this study, such as deterioration in seeking medical care for children with fever. Other factors that were not measured, such as the increasing resistance of malaria to drug treatment and the increased prevalence of parental HIV/AIDS, may be contributing

Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s

NASA Astrophysics Data System (ADS)

DU, Y.; Zhang, Y.

2016-02-01

A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004-2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate.

Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s

NASA Astrophysics Data System (ADS)

Du, Yan; Zhang, Yuhong; Feng, Ming; Wang, Tianyu; Zhang, Ningning; Wijffels, Susan

2015-11-01

A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004-2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate.

Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s

PubMed Central

Du, Yan; Zhang, Yuhong; Feng, Ming; Wang, Tianyu; Zhang, Ningning; Wijffels, Susan

2015-01-01

A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004–2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate. PMID:26522168

Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s.

PubMed

Du, Yan; Zhang, Yuhong; Feng, Ming; Wang, Tianyu; Zhang, Ningning; Wijffels, Susan

2015-11-02

A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004-2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate.

Novel Coupled Thermochronometric and Geochemical Investigation of Blind Geothermal Resources in Fault-Controlled Dilational Corners

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stockli, Daniel

Geothermal plays in extensional and transtensional tectonic environments have long been a major target in the exploration of geothermal resources and the Dixie Valley area has served as a classic natural laboratory for this type of geothermal plays. In recent years, the interactions between normal faults and strike-slip faults, acting either as strain relay zones have attracted significant interest in geothermal exploration as they commonly result in fault-controlled dilational corners with enhanced fracture permeability and thus have the potential to host blind geothermal prospects. Structural ambiguity, complications in fault linkage, etc. often make the selection for geothermal exploration drilling targetsmore » complicated and risky. Though simplistic, the three main ingredients of a viable utility-grade geothermal resource are heat, fluids, and permeability. Our new geological mapping and fault kinematic analysis derived a structural model suggest a two-stage structural evolution with (a) middle Miocene N -S trending normal faults (faults cutting across the modern range), - and tiling Olio-Miocene volcanic and sedimentary sequences (similar in style to East Range and S Stillwater Range). NE-trending range-front normal faulting initiated during the Pliocene and are both truncating N-S trending normal faults and reactivating some former normal faults in a right-lateral fashion. Thus the two main fundamental differences to previous structural models are (1) N-S trending faults are pre-existing middle Miocene normal faults and (2) these faults are reactivated in a right-later fashion (NOT left-lateral) and kinematically linked to the younger NE-trending range-bounding normal faults (Pliocene in age). More importantly, this study provides the first constraints on transient fluid flow through the novel application of apatite (U-Th)/He (AHe) and 4He/ 3He thermochronometry in the geothermally active Dixie Valley area in Nevada.« less

Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Performance Verification Report: METSAT (S/N 108) AMSU-A1 Receiver Assemblies, P/N 1356429-1 S/N F05 and P/N 1356409-1 S/N F05

NASA Technical Reports Server (NTRS)

Haigh, R.; Krimchansky, S. (Technical Monitor)

2000-01-01

This is the Performance Verification Report, METSAT (S/N 108) AMSU-A1 Receiver Assemblies P/N 1356429-1 S/N F05 and P/N 1356409-1 S/N F05, for the Integrated Advanced Microwave Sounding Unit-A (AMSU-A). The ATP for the AMSU-A Receiver Subsystem, AE-26002/6A, is prepared to describe in detail the configuration of the test setups and the procedures of the tests to verify that the receiver subsystem meets the specifications as required either in the AMSU-A Instrument Performance and Operation Specifications, S-480-80, or in AMSU-A Receiver Subsystem Specifications, AE-26608, derived by the Aerojet System Engineering. Test results that verify the conformance to the specifications demonstrate the acceptability of that particular receiver subsystem.

Normal paraspinal muscle electromyographic fatigue characteristics in patients with primary fibromyalgia.

PubMed

Stokes, M J; Colter, C; Klestov, A; Cooper, R G

1993-08-01

Paraspinal muscle fatigue mechanisms were compared in 14 primary fibromyalgia patients and 14 age and sex matched normal subjects using a standardized 60-s isometric endurance test of the paraspinal muscles, during which surface integrated electromyographic (IEMG) activity was recorded. Fatigue-induced IEMG increases were similar for both groups during the initial 40 s (up to 112 +/- 20% and 111 +/- 6% of initial values in patients and normal subjects respectively). Thereafter, IEMG fell significantly in patients (P < 0.05) but only slightly in controls, so that at 58 s IEMG was 102 +/- 13% in patients and 109 +/- 12% in controls. If patients were divided according to body mass index (BMI, range 19-25 in controls) those with a BMI < 26 (n = 5) showed IEMG changes similar to those of control subjects throughout the test, while obese patients with BMI > 26 (n = 9) showed greater IEMG declines after 40 s than either normal subjects or in the fibromyalgia group as a whole. Paraspinal muscle fatigue mechanisms appear normal in primary fibromyalgia patients. Isometric force maintenance in overweight patients, despite IEMG declines, illustrates the action of intrinsic fatigue resistance mechanisms which were presumably utilized to a greater extent in these patients to cope with the extra load.

Influence of electronegativity on the electronic structures and stabilities of microclusters of carbides MC_n (M : transition, rare-earth or normal element, n < 10)

NASA Astrophysics Data System (ADS)

Leleyter, M.

1991-10-01

infer a likely electronic configuration of the MC_n clusters and 2 tables give the compared electronic structures of these clusters for normal or transition elements. Such a kind of structure is only able to explain the parity effect origin of the MC_n clusters and even enable to foreknow for transition or rare-earth metal carbides which are not studied yet if the alternations will be “even" (EN le 1.7) or “odd". Les agrégats MC_n obtenus à partir de carbures par diverses méthodes expérimentales (SIMS, SSMS, vaporisation laser, effusion de Knudsen à haute température, etc.) présentent des alternances dans leurs intensités d'émission I(MC^+_n) avec maximums pour n impair si M = H, F, CI ou Fe, Ni, Rh, Ir, Pt ou au contraire pour n pair si M = B, Si, Ba, Ge ou Sc, Ti, V, Cr, Y, Zr, La, Ce, W, Th, U ou même n'existent que pour n pair (Nd, Dy, Ho, Er). D'autre part, seuls sont connus CO, C_3O, CN et C_3N pour l'oxygène et l'azote. Ces phénomènes sont interprétés tout d'abord à l'aide de la règle bien connue de correspondance qui relie de fortes (resp. faibles) intensités ou fréquences d'émissions d'ions MC^+_n à de fortes (resp. faibles) stabilités des amas correspondants. En second lieu, ces résultats s'expliquent dans le cadre du modèle de Pitzer et Clementi (hybridation sp en théorie de Hückel) corroboré par des calculs CNDO: on suppose que les amas MC^+_n sont des chaînes linéaires C^+_n portant un atome d'impureté M en bout de chaîne. Dans ces conditions, les alternances de stabilités relatives des MC_n proviennent de ce que l'orbitale moléculaire la plus élevée (“ HOMO ”) se trouve dans une bande niveaux π doublement dégénérés et qu'à une orbitale π complète (4 électrons) correspond une plus forte stabilité de l'amas que si l'orbitale est incomplète. Or le nombre d'électrons π d'une chaîne MC_n est gouverné par le nombre de niveaux σ liants et en outre pour les éléments de transition ou de terres rares, par

A new EEG synchronization strength analysis method: S-estimator based normalized weighted-permutation mutual information.

PubMed

Cui, Dong; Pu, Weiting; Liu, Jing; Bian, Zhijie; Li, Qiuli; Wang, Lei; Gu, Guanghua

2016-10-01

Synchronization is an important mechanism for understanding information processing in normal or abnormal brains. In this paper, we propose a new method called normalized weighted-permutation mutual information (NWPMI) for double variable signal synchronization analysis and combine NWPMI with S-estimator measure to generate a new method named S-estimator based normalized weighted-permutation mutual information (SNWPMI) for analyzing multi-channel electroencephalographic (EEG) synchronization strength. The performances including the effects of time delay, embedding dimension, coupling coefficients, signal to noise ratios (SNRs) and data length of the NWPMI are evaluated by using Coupled Henon mapping model. The results show that the NWPMI is superior in describing the synchronization compared with the normalized permutation mutual information (NPMI). Furthermore, the proposed SNWPMI method is applied to analyze scalp EEG data from 26 amnestic mild cognitive impairment (aMCI) subjects and 20 age-matched controls with normal cognitive function, who both suffer from type 2 diabetes mellitus (T2DM). The proposed methods NWPMI and SNWPMI are suggested to be an effective index to estimate the synchronization strength. Copyright © 2016 Elsevier Ltd. All rights reserved.

Groundwater-level trends in the U.S. glacial aquifer system, 1964-2013

USGS Publications Warehouse

Hodgkins, Glenn A.; Dudley, Robert W.; Nielsen, Martha G.; Renard, Benjamin; Qi, Sharon L.

2017-01-01

The glacial aquifer system in the United States is a major source of water supply but previous work on historical groundwater trends across the system is lacking. Trends in annual minimum, mean, and maximum groundwater levels for 205 monitoring wells were analyzed across three regions of the system (East, Central, West Central) for four time periods: 1964-2013, 1974-2013, 1984-2013, and 1994-2013. Trends were computed separately for wells in the glacial aquifer system with low potential for human influence on groundwater levels and ones with high potential influence from activities such as groundwater pumping. Generally there were more wells with significantly increasing groundwater levels (levels closer to ground surface) than wells with significantly decreasing levels. The highest numbers of significant increases for all four time periods were with annual minimum and/or mean levels. There were many more wells with significant increases from 1964 to 2013 than from more recent periods, consistent with low precipitation in the 1960s. Overall there were low numbers of wells with significantly decreasing trends regardless of time period considered; the highest number of these were generally for annual minimum groundwater levels at wells with likely human influence. There were substantial differences in the number of wells with significant groundwater-level trends over time, depending on whether the historical time series are assumed to be independent, have short-term persistence, or have long-term persistence. Mean annual groundwater levels have significant lag-one-year autocorrelation at 26.0% of wells in the East region, 65.4% of wells in the Central region, and 100% of wells in the West Central region. Annual precipitation across the glacial aquifer system, on the other hand, has significant autocorrelation at only 5.5% of stations, about the percentage expected due to chance.

Some Current Population Trends.

ERIC Educational Resources Information Center

Taeuber, Conrad

Population trends in the 1960's and early 1970's are examined in this 1972 speech in terms of overall national trends, the growth of metropolitan areas, the rural population, geographic shifts, internal migration, the black population, and living arrangements. It is noted that population growth in the 1960's was unevenly distributed within age…

Supergravity backgrounds for deformations of AdS n × S n supercoset string models

DOE PAGES

Lunin, O.; Roiban, R.; Tseytlin, A. A.

2014-12-11

We considermore » type IIB supergravity backgrounds corresponding to the deformed AdS n × S n × T 10 - 2 n supercoset string models of the type constructed in arXiv:1309.5850[2] which depend on one deformation parameter κ. In AdS 2 × S 2 case we find that the deformed metric can be extended to a full supergravity solution with non-trivial dilaton, RR scalar and RR 5-form strength. The solution depends on a free parameter a that should be chosen as a particular function of κ to correspond to the deformed supercoset model. In AdS 3 × S 3 case the full solution supported by the dilaton, RR scalar and RR 3-form strength exists only in the two special cases, a = 0 and a = 1 . We conjecture that there may be a more general one-parameter solution supported by several RR fields that for particular a = a ( κ ) corresponds to the supercoset model. In the most complicated deformed AdS 5 × S 5 case we were able to find only the expressions for the dilaton and the RR scalar. The full solution is likely to be supported by a combination of the 5-form and 3-form field strengths. We comment on the singularity structure of the resulting metric and exact dilaton field.« less

Supergravity backgrounds for deformations of AdS n × S n supercoset string models

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lunin, O.; Roiban, R.; Tseytlin, A. A.

We considermore » type IIB supergravity backgrounds corresponding to the deformed AdS n × S n × T 10 - 2 n supercoset string models of the type constructed in arXiv:1309.5850[2] which depend on one deformation parameter κ. In AdS 2 × S 2 case we find that the deformed metric can be extended to a full supergravity solution with non-trivial dilaton, RR scalar and RR 5-form strength. The solution depends on a free parameter a that should be chosen as a particular function of κ to correspond to the deformed supercoset model. In AdS 3 × S 3 case the full solution supported by the dilaton, RR scalar and RR 3-form strength exists only in the two special cases, a = 0 and a = 1 . We conjecture that there may be a more general one-parameter solution supported by several RR fields that for particular a = a ( κ ) corresponds to the supercoset model. In the most complicated deformed AdS 5 × S 5 case we were able to find only the expressions for the dilaton and the RR scalar. The full solution is likely to be supported by a combination of the 5-form and 3-form field strengths. We comment on the singularity structure of the resulting metric and exact dilaton field.« less

Trends in urinary arsenic among the U.S. population by drinking water source: Results from the National Health and Nutritional Examinations Survey 2003-2014.

PubMed

Welch, Barrett; Smit, Ellen; Cardenas, Andres; Hystad, Perry; Kile, Molly L

2018-04-01

In 2001, the United States revised the arsenic maximum contaminant level for public drinking water systems from 50µg/L to 10µg/L. This study aimed to examine temporal trends in urinary arsenic concentrations in the U.S. population from 2003 to 2014 by drinking water source among individuals aged 12 years and older who had no detectable arsenobetaine - a biomarker of arsenic exposure from seafood intake. We examined data from 6 consecutive cycles of the National Health and Nutrition Examination Survey (2003-2014; N=5848). Total urinary arsenic (TUA) was calculated by subtracting arsenobetaine's limit of detection and detectable arsenocholine from total arsenic. Additional sensitivity analyses were conducted using a second total urinary arsenic index (TUA2, calculated by adding arsenite, arsenate, monomethylarsonic acid, dimethylarsinic acid). We classified drinking water source using 24-h dietary questionnaire data as community supply (n=3427), well or rain cistern (n=506), and did not drink tap water (n=1060). Geometric means (GM) of survey cycles were calculated from multivariate regression models adjusting for age, gender, race/ethnicity, BMI, income, creatinine, water source, type of water consumed, recent smoking, and consumption of seafood, rice, poultry, and juice. Compared to 2003-2004, adjusted TUA was 35.5% lower in 2013-2014 among the general U.S. Stratified analysis by smoking status indicated that the trend in lower TUA was only consistent among non-smokers. Compared to 2003-2004, lower adjusted TUA was observed in 2013-2014 among non-smoking participants who used community water supplies (1.98 vs 1.16µg/L, p<0.001), well or rain cistern users (1.54 vs 1.28µg/L, p<0.001) and who did not drink tap water (2.24 vs 1.53µg/L, p<0.001). Sensitivity analyses showed consistent results for participants who used a community water supplier and to a lesser extent those who did not drink tap water. However, the sensitivity analysis showed overall exposure

The Normalization of Cannabis Use Among Bangladeshi and Pakistani Youth: A New Frontier for the Normalization Thesis?

PubMed

Williams, Lisa; Ralphs, Rob; Gray, Paul

2017-03-21

The Asian population in Britain has grown, representing the second largest ethnic group; Bangladeshi, Pakistani, and Indian nationalities are prevalent (Jivraj, 2012 ; Office for National Statistics, 2013 ). Yet, we know relatively little about the nature and extent of their substance use. Jayakody et al. ( 2006 ) argue ethnic minority groups may be influenced by the norms and values of the dominant culture. Given recreational drug use has undergone a process of normalization in Britain (Aldridge et al., 2011 ; Parker et al., 1998 , 2002 ), we explore the degree to which this is occurring in a Bangladeshi and Pakistani community of Muslim faith in Northern England; a group typically assumed to reject substance use because of robust religious and cultural values. To examine the extent, frequency, and nature of substance use, and associated attitudes. A cross-sectional study collecting qualitative data from a sample (N = 43) of adolescents accessing a drug service and a range of professionals working with them during 2014. We also present analyses of routinely collected quantitative client data. Adolescent interviewees reported extensive personal experience smoking skunk cannabis, and professionals working in the community confirmed many young Asians smoked it. Its consumption appeared to be accommodated into the daily lives of young people and the supply of it also showed signs of acceptance. Skunk cannabis may be undergoing a process of normalization within some Asian communities in Britain. Our study has significant implications for the normalization thesis, finding evidence for normalization within a subpopulation that is typically perceived to resist this trend.

Diverse growth trends and climate responses across Eurasia’s boreal forest

NASA Astrophysics Data System (ADS)

Hellmann, Lena; Agafonov, Leonid; Charpentier Ljungqvist, Fredrik; Churakova (Sidorova, Olga; Düthorn, Elisabeth; Esper, Jan; Hülsmann, Lisa; Kirdyanov, Alexander V.; Moiseev, Pavel; Myglan, Vladimir S.; Nikolaev, Anatoly N.; Reinig, Frederick; Schweingruber, Fritz H.; Solomina, Olga; Tegel, Willy; Büntgen, Ulf

2016-07-01

The area covered by boreal forests accounts for ˜16% of the global and 22% of the Northern Hemisphere landmass. Changes in the productivity and functioning of this circumpolar biome not only have strong effects on species composition and diversity at regional to larger scales, but also on the Earth’s carbon cycle. Although temporal inconsistency in the response of tree growth to temperature has been reported from some locations at the higher northern latitudes, a systematic dendroecological network assessment is still missing for most of the boreal zone. Here, we analyze the geographical patterns of changes in summer temperature and precipitation across northern Eurasia >60 °N since 1951 AD, as well as the growth trends and climate responses of 445 Pinus, Larix and Picea ring width chronologies in the same area and period. In contrast to widespread summer warming, fluctuations in precipitation and tree growth are spatially more diverse and overall less distinct. Although the influence of summer temperature on ring formation is increasing with latitude and distinct moisture effects are restricted to a few southern locations, growth sensitivity to June-July temperature variability is only significant at 16.6% of all sites (p ≤ 0.01). By revealing complex climate constraints on the productivity of Eurasia’s northern forests, our results question the a priori suitability of boreal tree-ring width chronologies for reconstructing summer temperatures. This study further emphasizes regional climate differences and their role on the dynamics of boreal ecosystems, and also underlines the importance of free data access to facilitate the compilation and evaluation of massively replicated and updated dendroecological networks.

Outdoor recreation trends in the 1980's so what? - implications for society!

Treesearch

Carlton S. Van Doren

1980-01-01

My purpose today as the last speaker is twofold. I have been asked to summarize the many excellent presentations we have heard during the previous two days and to be a spokesman for society's viewpoint. It is my intent to challenge you. I hope to draw your attention to some implications concerning outdoor recreation trends in the 1980's that I foresee in this...

Trends in Tobacco Product Use Patterns Among U.S. Youth, 1999-2014.

PubMed

El-Toukhy, Sherine; Sabado, Melanie; Choi, Kelvin

2018-05-03

We examined trends in seven mutually exclusive tobacco product use patterns (T-PUPs) in nationally representative samples of U.S. youth over time and age. We used time varying effect modeling on National Youth Tobacco Surveys, 1999-2014 (N = 38662, 9-17 years, M = 15.02). Regression coefficients were estimated as a non-parametric function of time. T-PUPs were cigarette only, non-cigarette combustible only, noncombustible only, non-cigarette combustible and noncombustible dual, cigarette and noncombustible dual, cigarette and non-cigarette combustible dual, and POLY (i.e. cigarettes, non-cigarette combustibles, and noncombustibles) use. Among youth tobacco users, cigarette only use was the predominant T-PUP from 1999 to 2010. After 2010 and 2013, non-cigarette combustible only (AOR 1.38, CI = 1.02-1.87) and noncombustible only (AOR 1.57, CI = 1.00-2.45) use became more prevalent than cigarette only use. In 2011, dual and POLY T-PUPs were on the rise although not significantly different from cigarette only use. Cigarette only use was the predominant T-PUP among 11- to 17-year-old tobacco users. Non-cigarette combustible only (AOR 0.14, CI = 0.10-0.19), noncombustible only (AOR 0.01, CI = 0.008-0.02), non-cigarette combustible and noncombustible (AOR 0.01, CI = 0.01-0.03), cigarette and noncombustible (AOR 0.02, CI = 0.01-0.04), cigarette and non-cigarette combustible (AOR 0.32, CI = 0.24-0.43), and POLY (AOR 0.02, CI = 0.01-0.04) use were less prevalent than cigarette only use at age 17. Non-cigarette, dual, and POLY T-PUPs are rising among youth tobacco users. Screening for all tobacco use and delivering treatment during pediatrician visits should be standard clinical practice. Tracking trends in tobacco product use patterns (T-PUPs) over time and age is necessary to achieve Healthy People 2020 goal of reducing tobacco use among youth. Trends over time show a rise of non-cigarette T-PUPs especially noncombustible products but cigarette only use remains the most

Normally-off AlGaN/GaN-based MOS-HEMT with self-terminating TMAH wet recess etching

NASA Astrophysics Data System (ADS)

Son, Dong-Hyeok; Jo, Young-Woo; Won, Chul-Ho; Lee, Jun-Hyeok; Seo, Jae Hwa; Lee, Sang-Heung; Lim, Jong-Won; Kim, Ji Heon; Kang, In Man; Cristoloveanu, Sorin; Lee, Jung-Hee

2018-03-01

Normally-off AlGaN/GaN-based MOS-HEMT has been fabricated by utilizing damage-free self-terminating tetramethyl ammonium hydroxide (TMAH) recess etching. The device exhibited a threshold voltage of +2.0 V with good uniformity, extremely small hysteresis of ∼20 mV, and maximum drain current of 210 mA/mm. The device also exhibited excellent off-state performances, such as breakdown voltage of ∼800 V with off-state leakage current as low as ∼10-12 A and high on/off current ratio (Ion/Ioff) of 1010. These excellent device performances are believed to be due to the high quality recessed surface, provided by the simple self-terminating TMAH etching.

Near N-S paleo-extension in the western Deccan region, India: Does it link strike-slip tectonics with India-Seychelles rifting?

NASA Astrophysics Data System (ADS)

Misra, Achyuta Ayan; Bhattacharya, Gourab; Mukherjee, Soumyajit; Bose, Narayan

2014-09-01

This is the first detailed report and analyses of deformation from the W part of the Deccan large igneous province (DLIP), Maharashtra, India. This deformation, related to the India-Seychelles rifting during Late Cretaceous-Early Paleocene, was studied, and the paleostress tensors were deduced. Near N-S trending shear zones, lineaments, and faults were already reported without significant detail. An E-W extension was envisaged by the previous workers to explain the India-Seychelles rift at ~64 Ma. The direction of extension, however, does not match with their N-S brittle shear zones and also those faults (sub-vertical, ~NE-SW/~NW-SE, and few ~N-S) we report and emphasize in this work. Slickenside-bearing fault planes, brittle shear zones, and extension fractures in meso-scale enabled us to estimate the paleostress tensors (directions and relative magnitudes). The field study was complemented by remote sensing lineament analyses to map dykes and shear zones. Dykes emplaced along pre-existing ~N-S to ~NE-SW/~NW-SE shears/fractures. This information was used to derive regional paleostress trends. A ~NW-SE/NE-SW minimum compressive stress in the oldest Kalsubai Subgroup and a ~N-S direction for the younger Lonavala, Wai, and Salsette Subgroups were deciphered. Thus, a ~NW/NE to ~N-S extension is put forward that refutes the popular view of E-W India-Seychelles extension. Paleostress analyses indicate that this is an oblique rifted margin. Field criteria suggest only ~NE-SW and ~NW-SE, with some ~N-S strike-slip faults/brittle shear zones. We refer this deformation zone as the "Western Deccan Strike-slip Zone" (WDSZ). The observed deformation was matched with offshore tectonics deciphered mainly from faults interpreted on seismic profiles and from magnetic seafloor spreading anomalies. These geophysical findings too indicate oblique rifting in this part of the W Indian passive margin. We argue that the Seychelles microcontinent separated from India only after much of

Analysis and interpretation of water-quality trends in major U.S. rivers, 1974-81

USGS Publications Warehouse

Smith, Richard A.; Alexander, Richard B.; Wolman, M. Gordon

1987-01-01

Water-quality records from two nationwide sampling networks are now of sufficient length to permit nationally consistent analysis of long-term water-quality trends at more than 300 locations on major U.S. rivers. Observed trends in 24 water-quality measures for the period 1974--81 provide evidence of both improvement and deterioration in stream quality during a time of major changes in atmospheric and terrestrial influences on surface waters. Particularly noteworthy are widespread decreases in lead and fecal bacteria concentrations and widespread increases in nitrate, arsenic, and cadmium concentrations. Changes in municipal waste treatment, leaded-gasoline consumption, highway-salt use, and nitrogen-fertilizer application, and regionally variable trends in coal production and combustion during the period, appear to be reflected in water-quality changes. There is evidence that atmospheric deposition of a variety of substances has played a surprisingly large role in water-quality changes.

Trends in NRMP Data from 2007-2014 for U.S. Seniors Matching into Emergency Medicine.

PubMed

Manthey, David E; Hartman, Nicholas D; Newmyer, Aileen; Gunalda, Jonah C; Hiestand, Brian C; Askew, Kim L; Lefebvre, Cedric

2017-01-01

Since 1978, the National Residency Matching Program (NRMP) has published data demonstrating characteristics of applicants who have matched into their preferred specialty in the NRMP main residency match. These data have been published approximately every two years. There is limited information about trends within these published data for students matching into emergency medicine (EM). Our objective was to investigate and describe trends in NRMP data to include the following: the ratio of applicants to available EM positions; United State Medical Licensing Examination (USMLE) Step 1 and Step 2 scores (compared to the national means); number of programs ranked; and Alpha Omega Alpha Honor Medical Society (AOA) membership among U.S. seniors matching into EM. This was a retrospective observational review of NRMP data published between 2007 and 2016. We analyzed the data using analysis of variance (ANOVA) or Kruskal-Wallis testing, and Fischer's exact or chi-squared testing, as appropriate to determine statistical significance. The ratio of applicants to available EM positions remained essentially stable from 2007 to 2014 but did increase slightly in 2016. We observed a net upward trend in overall Step 1 and Step 2 scores for EM applicants. However, this did not outpace the national trend increase in Step 1 and 2 scores overall. There was an increase in the mean number of programs ranked by EM applicants over the years studied from 7.8 (SD4.2) to 9.2 (SD5.0, p<0.001), driven predominantly by the cohort of U.S. students successful in the match. Among time intervals, there was a difference in the number of EM applicants with AOA membership (p=0.043) due to a drop in the number of AOA students in 2011. No sustained statistical trend in AOA membership was identified over the seven-year period studied. NRMP data demonstrate trends among EM applicants that are similar to national trends in other specialties for USMLE board scores, and a modest increase in number of programs

Trends in age verification among U.S. adolescents attempting to buy cigarettes at retail stores, 2000-2009.

PubMed

Filippidis, Filippos T; Agaku, Israel T; Connolly, Gregory N; Vardavas, Constantine I

2014-04-01

This study assessed trends in age verification prior to cigarette sales to U.S. middle and high school students, and refusal to sell cigarettes to students aged <18 years during 2000-2009. Data were obtained from the 2000-2009 National Youth Tobacco Survey. Trends during 2000-2009 were assessed using binary logistic regression (p<0.05). The proportion of all students, who reported being asked to show proof of age prior to a cigarette purchase in the past 30 days did not change significantly between 2000 (46.9%) and 2009 (44.9%) (p=0.529 for linear trend). No significant trend in the proportion of students aged < 18 years who were refused a sale when attempting to buy cigarettes was observed between 2000 (39.8%) and 2009 (36.7%) (p=0.283 for linear trend). Refusal of a cigarette sale was significantly higher among under-aged boys compared to girls (adjusted odds ratio=1.48; 95% confidence interval: 1.28-1.70). About half of U.S. middle and high school students who reported making a cigarette purchase were not asked for proof of age, and about three of five under-aged buyers successfully made a cigarette purchase in 2009. Intensified implementation and enforcement of policies requiring age verification among youths is warranted to reduce access and use of tobacco products. Copyright © 2014 Elsevier Inc. All rights reserved.

Gender and Racial Pay Gaps in the 1980s: Accounting for Different Trends. Final Report. Researching Women in the Workplace.

ERIC Educational Resources Information Center

Sorensen, Elaine

Two contrasting trends concerning gender and racial wage levels for U.S. workers emerged in the 1980s. The first trend, which is gender-related, is that women made tremendous gains in their wages relative to those of men: in 1978 women earned 61 percent as much as men, while by 1990 that figure rose to 72 percent. Furthermore, these gains extended…

Trends in Health Information-Seeking Behaviour in the U.S. Foreign-Born Population Based on the Health Information National Trends Survey, 2005-2014

ERIC Educational Resources Information Center

Yoon, JungWon; Huang, Hong; Soojung Kim

2017-01-01

Introduction: This study investigated trends in the health information-seeking behaviour of the U.S. foreign-born population over a ten-year period and examined whether health information disparities between this population and native-born citizens have decreased. Method: Data were collected from six iterations of the Health Information National…

Development of the method and U.S. normalization database for Life Cycle Impact Assessment and sustainability metrics.

PubMed

Bare, Jane; Gloria, Thomas; Norris, Gregory

2006-08-15

Normalization is an optional step within Life Cycle Impact Assessment (LCIA) that may be used to assist in the interpretation of life cycle inventory data as well as life cycle impact assessment results. Normalization transforms the magnitude of LCI and LCIA results into relative contribution by substance and life cycle impact category. Normalization thus can significantly influence LCA-based decisions when tradeoffs exist. The U. S. Environmental Protection Agency (EPA) has developed a normalization database based on the spatial scale of the 48 continental U.S. states, Hawaii, Alaska, the District of Columbia, and Puerto Rico with a one-year reference time frame. Data within the normalization database were compiled based on the impact methodologies and lists of stressors used in TRACI-the EPA's Tool for the Reduction and Assessment of Chemical and other environmental Impacts. The new normalization database published within this article may be used for LCIA case studies within the United States, and can be used to assist in the further development of a global normalization database. The underlying data analyzed for the development of this database are included to allow the development of normalization data consistent with other impact assessment methodologies as well.

The COBE normalization for standard cold dark matter

NASA Technical Reports Server (NTRS)

Bunn, Emory F.; Scott, Douglas; White, Martin

1995-01-01

The Cosmic Background Explorer Satellite (COBE) detection of microwave anisotropies provides the best way of fixing the amplitude of cosmological fluctuations on the largest scales. This normalization is usually given for an n = 1 spectrum, including only the anisotropy caused by the Sachs-Wolfe effect. This is certainly not a good approximation for a model containing any reasonable amount of baryonic matter. In fact, even tilted Sachs-Wolfe spectra are not a good fit to models like cold dark matter (CDM). Here, we normalize standard CDM (sCDM) to the two-year COBE data and quote the best amplitude in terms of the conventionally used measures of power. We also give normalizations for some specific variants of this standard model, and we indicate how the normalization depends on the assumed values on n, Omega(sub B) and H(sub 0). For sCDM we find the mean value of Q = 19.9 +/- 1.5 micro-K, corresponding to sigma(sub 8) = 1.34 +/- 0.10, with the normalization at large scales being B = (8.16 +/- 1.04) x 10(exp 5)(Mpc/h)(exp 4), and other numbers given in the table. The measured rms temperature fluctuation smoothed on 10 deg is a little low relative to this normalization. This is mainly due to the low quadrupole in the data: when the quadrupole is removed, the measured value of sigma(10 deg) is quite consistent with the best-fitting the mean value of Q. The use of the mean value of Q should be preferred over sigma(10 deg), when its value can be determined for a particular theory, since it makes full use of the data.

Demographic Trends in the United States: A Review of Research in the 2000s

ERIC Educational Resources Information Center

Cherlin, Andrew J.

2010-01-01

Demographic trends in the 2000s showed the continuing separation of family and household because of factors such as childbearing among single parents, the dissolution of cohabiting unions, divorce, repartnering, and remarriage. The transnational families of many immigrants also displayed this separation, as families extended across borders. In…

Trends in bullying victimization by gender among U.S. high school students.

PubMed

Pontes, Nancy M H; Ayres, Cynthia G; Lewandowski, Carla; Pontes, Manuel C F

2018-06-01

This research used four consecutive waves of data from the National Youth Risk Behavior Survey (YRBS) conducted by the Centers for Disease Control (CDC), to estimate linear time trends by gender in the prevalence of school and electronic bullying victimization among U.S. high school students (N = 61,042). Dependent variables were student self-reported school bullying victimization and electronic bullying victimization during the previous 12 months. Independent variables used to estimate multiple logistic regression models by gender were survey year, race/ethnicity, and grade level. Results showed the prevalence of school bullying increased significantly among females from 2009 (21.2%) to 2015 (24.8%), linear trend OR = 1.08 [1.04, 1.12]; and decreased significantly among males from 2009 (18.7%) to 2015 (15.8%), linear trend OR = 0.93 [0.89, 0.98]. Prevalence of electronic bullying was unchanged between 2011 to 2015 among both male and female students. Asian race, relative to White race, was associated with significantly lower rates of both school and electronic bullying victimization among females, but not males. The incidence of school and electronic bullying victimization was significantly lower among Black and Hispanic students, but not among multiple-race students, regardless of student gender. Healthy People 2020 set a goal to reduce school bullying victimization 10% by 2019. As of 2015, school bullying victimization decreased significantly among males (16% decrease); it significantly increased among females (17% increase). Future research should explore underlying factors related to these divergent trends, and develop effective strategies to reverse the alarming rise in female school bullying victimization. © 2018 Wiley Periodicals, Inc.

Akron Perkins Normal School: An Institutional History, 1898-1931.

ERIC Educational Resources Information Center

Kline, Melinda J.

The preparation of elementary school teachers in the middle and late 19th century increasingly included city normal training schools. The city school board of Akron, Ohio, reflected this trend and established its own normal training school in 1898. This paper documents the preservice training of teachers within the city training school, the…

International Adoption in the U. S: Traumatic Stress and Normal Developmental Responses

ERIC Educational Resources Information Center

Wolfgang, Jeff Drayton

2011-01-01

The purpose of this paper is to present a review of literature on internationally adopted children in the U.S. that provides context, references for normal development, and describes traumatic stress with children. This gives counselors and other professionals who work with young children and families of international adoption a conceptual…

Electron impact excitation of the q{sup 1}S {r_arrow}n{sup 1}P (n=3,4) transitions in helium

DOE Office of Scientific and Technical Information (OSTI.GOV)

Khakoo, M.A.; Rugamas, F.; Roundy, D.

1996-05-01

Experimental differential cross-section (DCS) ratios for the above transitions to the 1{sup 1}S {r_arrow} 2{sup 1}P transition are reported at impact energies of 30eV, 40eV and 80eV and scattering angles in the range of 5{degrees} to 130{degrees}. The data are an extension of previously reported work using the electron-photon coincidence method in the VUV. The DCS ratios are normalized to available absolute DCSs for the 1{sup 1}S {r_arrow} 2{sup 1}P transition and the resulting n{sup 1}P DCSs are compared to previous semi-empirical DCSs as well as available theory.

Amniotic fluid sTREM-1 in normal pregnancy, spontaneous parturition at term and preterm, and intra-amniotic infection/inflammation

PubMed Central

Kusanovic, Juan Pedro; Romero, Roberto; Chaiworapongsa, Tinnakorn; Mittal, Pooja; Mazaki-Tovi, Shali; Vaisbuch, Edi; Erez, Offer; Gotsch, Francesca; Than, Nandor Gabor; Edwin, Sam S.; Pacora, Percy; Jodicke, Cristiano; Yeo, Lami; Hassan, Sonia S.

2010-01-01

Objective Intra-amniotic infection/inflammation (IAI) is one of the most important mechanisms of disease in preterm birth. Triggering receptor expressed on myeloid cells (TREM)-1 is a transmembrane glycoprotein expressed by neutrophils, macrophages and mature monocytes. TREM-1 is upregulated in biological fluids and tissues infected by Gram (+) and Gram (-) bacteria and fungi, amplifies the production of pro-inflammatory cytokines and chemokines, and its soluble form (sTREM-1) is released in the presence of infection. The aim of this study was to determine the effect of gestational age, parturition (term and preterm) and intra-amniotic infection/inflammation in the amniotic fluid (AF) concentrations of sTREM-1. Study design This cross-sectional study included 434 patients in the following groups: 1) mid-trimester of pregnancy (14-18 weeks, n=38); 2) normal pregnant women at term with (n=39) and without (n=39) labor; 3) patients with spontaneous preterm labor (PTL) and intact membranes classified into: a) PTL who delivered at term (n=99); b) PTL who delivered preterm (<37 weeks gestation) without IAI (n=80); and c) PTL with IAI (n=59); and 4) women with preterm prelabor rupture of membranes (PROM) with (n=40) and without (n=40) IAI. The AF concentration of sTREM-1 was determined by enzyme-linked immunoassay. Non-parametric statistics were used for analyses. Results 1) sTREM-1 was detected in all AF samples; 2) the median AF sTREM-1 concentration at term was higher than in the mid-trimester (4277.6 pg/mL vs. 1140.4 pg/mL; p<0.001); 3) among patients with PTL, the median AF sTREM-1 concentration was significantly higher in patients with IAI than in those without IAI (6154.4 pg/mL vs. 3282.8 pg/mL; p<0.001) and those with PTL who delivered at term (6154.4 pg/mL vs. 2794 pg/mL; p<0.001); 4) patients with preterm PROM with IAI had a higher median AF sTREM-1 concentration than those without IAI (7893.1 pg/mL vs. 3386.6 pg/mL; p<0.001); 5) no differences were observed in

Trend indicators needed for effective recreation planning - a statistical blueprint for the 80's

Treesearch

H. Fred Kaiser; George H. Moeller

1980-01-01

Here we outline important elements in recreation planning and describe how the process is changing, using Federal land management agencies as our example. We outline some factors that will impact on planning in the 80's, encourage establishment of a system to monitor trends in key factors that influence recreation behavior.

Measurement of the normalized U 238 ( n , f ) / U 235 ( n , f ) cross section ratio from threshold to 30 MeV with the NIFFTE fission Time Projection Chamber

DOE PAGES

Casperson, R. J.; Asner, D. M.; Baker, J.; ...

2018-03-23

We present that the normalized 238U(n,f)/ 235U(n,f) cross section ratio has been measured using the NIFFTE fission Time Projection Chamber (fissionTPC) from the reaction threshold to 30 MeV . The fissionTPC is a two-volume MICROMEGAS time projection chamber that allows for full three-dimensional reconstruction of fission-fragment ionization profiles from neutron-induced fission. The measurement was performed at the Los Alamos Neutron Science Center, where the neutron energy is determined from neutron time of-flight. The 238U(n,f)/ 235U(n,f) ratio reported here is the first cross section measurement made with the fissionTPC, and will provide new experimental data for evaluation of the 238U(n,f) crossmore » section, an important standard used in neutron-flux measurements. Use of a development target in this work prevented the determination of an absolute normalization, to be addressed in future measurements. Instead, the measured cross section ratio has been normalized to ENDF/B-VIII.β5 at 14.5 MeV.« less

Measurement of the normalized 238U(n ,f )/235U(n ,f ) cross section ratio from threshold to 30 MeV with the NIFFTE fission Time Projection Chamber

NASA Astrophysics Data System (ADS)

Casperson, R. J.; Asner, D. M.; Baker, J.; Baker, R. G.; Barrett, J. S.; Bowden, N. S.; Brune, C.; Bundgaard, J.; Burgett, E.; Cebra, D. A.; Classen, T.; Cunningham, M.; Deaven, J.; Duke, D. L.; Ferguson, I.; Gearhart, J.; Geppert-Kleinrath, V.; Greife, U.; Grimes, S.; Guardincerri, E.; Hager, U.; Hagmann, C.; Heffner, M.; Hensle, D.; Hertel, N.; Higgins, D.; Hill, T.; Isenhower, L. D.; King, J.; Klay, J. L.; Kornilov, N.; Kudo, R.; Laptev, A. B.; Loveland, W.; Lynch, M.; Lynn, W. S.; Magee, J. A.; Manning, B.; Massey, T. N.; McGrath, C.; Meharchand, R.; Mendenhall, M. P.; Montoya, L.; Pickle, N. T.; Qu, H.; Ruz, J.; Sangiorgio, S.; Schmitt, K. T.; Seilhan, B.; Sharma, S.; Snyder, L.; Stave, S.; Tate, A. C.; Tatishvili, G.; Thornton, R. T.; Tovesson, F.; Towell, D. E.; Towell, R. S.; Walsh, N.; Watson, S.; Wendt, B.; Wood, L.; Yao, L.; Younes, W.; Niffte Collaboration

2018-03-01

The normalized 238U(n ,f )/235U(n ,f ) cross section ratio has been measured using the NIFFTE fission Time Projection Chamber (fissionTPC) from the reaction threshold to 30 MeV . The fissionTPC is a two-volume MICROMEGAS time projection chamber that allows for full three-dimensional reconstruction of fission-fragment ionization profiles from neutron-induced fission. The measurement was performed at the Los Alamos Neutron Science Center, where the neutron energy is determined from neutron time of-flight. The 238U(n ,f )/235U(n ,f ) ratio reported here is the first cross section measurement made with the fissionTPC, and will provide new experimental data for evaluation of the 238U(n ,f ) cross section, an important standard used in neutron-flux measurements. Use of a development target in this work prevented the determination of an absolute normalization, to be addressed in future measurements. Instead, the measured cross section ratio has been normalized to ENDF/B-VIII.β 5 at 14.5 MeV.

Measurement of the normalized U 238 ( n , f ) / U 235 ( n , f ) cross section ratio from threshold to 30 MeV with the NIFFTE fission Time Projection Chamber

DOE Office of Scientific and Technical Information (OSTI.GOV)

Casperson, R. J.; Asner, D. M.; Baker, J.

We present that the normalized 238U(n,f)/ 235U(n,f) cross section ratio has been measured using the NIFFTE fission Time Projection Chamber (fissionTPC) from the reaction threshold to 30 MeV . The fissionTPC is a two-volume MICROMEGAS time projection chamber that allows for full three-dimensional reconstruction of fission-fragment ionization profiles from neutron-induced fission. The measurement was performed at the Los Alamos Neutron Science Center, where the neutron energy is determined from neutron time of-flight. The 238U(n,f)/ 235U(n,f) ratio reported here is the first cross section measurement made with the fissionTPC, and will provide new experimental data for evaluation of the 238U(n,f) crossmore » section, an important standard used in neutron-flux measurements. Use of a development target in this work prevented the determination of an absolute normalization, to be addressed in future measurements. Instead, the measured cross section ratio has been normalized to ENDF/B-VIII.β5 at 14.5 MeV.« less

The Detection of Emerging Trends Using Wikipedia Traffic Data and Context Networks

PubMed Central

Kämpf, Mirko; Tessenow, Eric; Kenett, Dror Y.; Kantelhardt, Jan W.

2015-01-01

Can online media predict new and emerging trends, since there is a relationship between trends in society and their representation in online systems? While several recent studies have used Google Trends as the leading online information source to answer corresponding research questions, we focus on the online encyclopedia Wikipedia often used for deeper topical reading. Wikipedia grants open access to all traffic data and provides lots of additional (semantic) information in a context network besides single keywords. Specifically, we suggest and study context-normalized and time-dependent measures for a topic’s importance based on page-view time series of Wikipedia articles in different languages and articles related to them by internal links. As an example, we present a study of the recently emerging Big Data market with a focus on the Hadoop ecosystem, and compare the capabilities of Wikipedia versus Google in predicting its popularity and life cycles. To support further applications, we have developed an open web platform to share results of Wikipedia analytics, providing context-rich and language-independent relevance measures for emerging trends. PMID:26720074

46 CFR 401.428 - Basic rates and charges for carrying a U.S. pilot beyond normal change point or for boarding at...

Code of Federal Regulations, 2011 CFR

2011-10-01

... normal change point or for boarding at other than the normal boarding point. 401.428 Section 401.428... carrying a U.S. pilot beyond normal change point or for boarding at other than the normal boarding point. If a U.S. pilot is carried beyond the normal change point or is unable to board at the normal...

Trichohyalin-like 1 protein, a member of fused S100 proteins, is expressed in normal and pathologic human skin

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yamakoshi, Takako; Makino, Teruhiko, E-mail: tmakino@med.u-toyama.ac.jp; Ur Rehman, Mati

2013-03-01

Highlights: ► Trichohyalin-like 1 protein is a member of the fused-type S100 protein gene family. ► Specific antibodies against the C-terminus of the TCHHL1 protein were generated. ► TCHHL1 proteins were expressed in the basal layer of the normal epidermis. ► TCHHL1 proteins were strongly expressed in tumor nests of BCC and SCC. ► The expression of TCHHL1 proteins increased in epidermis of psoriasis vulgaris. - Abstract: Trichohyalin-like 1 (TCHHL1) protein is a novel member of the fused-type S100 protein gene family. The deduced amino acid sequence of TCHHL1 contains an EF-hand domain in the N-terminus, one trans-membrane domain andmore » a nuclear localization signal. We generated specific antibodies against the C-terminus of the TCHHL1 protein and examined the expression of TCHHL1 proteins in normal and pathological human skin. An immunohistochemical study showed that TCHHL1 proteins were expressed in the basal layer of the normal epidermis. In addition, signals of TCHHL1 proteins were observed around the nuclei of cultured growing keratinocytes. Accordingly, TCHHL1 mRNA has been detected in normal skin and cultured growing keratinocytes. Furthermore, TCHHL1 proteins were strongly expressed in the peripheral areas of tumor nests in basal cell carcinomas and squamous cell carcinomas. A dramatic increase in the number of Ki67 positive cells was observed in TCHHL1-expressing areas. The expression of TCHHL1 proteins also increased in non-cancerous hyperproliferative epidermal tissues such as those of psoriasis vulgaris and lichen planus. These findings highlight the possibility that TCHHL1 proteins are expressed in growing keratinocytes of the epidermis and might be associated with the proliferation of keratinocytes.« less

Expression profiles of SnoN in normal and cancerous human tissues support its tumor suppressor role in human cancer.

PubMed

Jahchan, Nadine S; Ouyang, Gaoliang; Luo, Kunxin

2013-01-01

SnoN is a negative regulator of TGF-β signaling and also an activator of the tumor suppressor p53 in response to cellular stress. Its role in human cancer is complex and controversial with both pro-oncogenic and anti-oncogenic activities reported. To clarify its role in human cancer and provide clinical relevance to its signaling activities, we examined SnoN expression in normal and cancerous human esophageal, ovarian, pancreatic and breast tissues. In normal tissues, SnoN is expressed in both the epithelium and the surrounding stroma at a moderate level and is predominantly cytoplasmic. SnoN levels in all tumor epithelia examined are lower than or similar to that in the matched normal samples, consistent with its anti-tumorigenic activity in epithelial cells. In contrast, SnoN expression in the stroma is highly upregulated in the infiltrating inflammatory cells in high-grade esophageal and ovarian tumor samples, suggesting that SnoN may potentially promote malignant progression through modulating the tumor microenvironment in these tumor types. The overall levels of SnoN expression in these cancer tissues do not correlate with the p53 status. However, in human cancer cell lines with amplification of the snoN gene, a strong correlation between increased SnoN copy number and inactivation of p53 was detected, suggesting that the tumor suppressor SnoN-p53 pathway must be inactivated, either through downregulation of SnoN or inactivation of p53, in order to allow cancer cell to proliferate and survive. These data strongly suggest that SnoN can function as a tumor suppressor at early stages of tumorigenesis in human cancer tissues.

New England's travel & tourism markets: trends in the geographic target markets in the 90's

Treesearch

Rodney B. Warnick

2001-01-01

The purpose of this paper was to examine the travel and lifestyle activity market trends to New England in the 90s. The central theme was to fully examine in detail the primary, secondary and tertiary geographic markets targeted by New England destinations.

Status and trends of dissolved oxygen in Corpus Christi Bay, Texas, U.S.A.

PubMed

Applebaum, Sally; Montagna, Paul A; Ritter, Christine

2005-08-01

The purpose of this study was to determine status and long-term trends of dissolved oxygen concentrations (DO) in Corpus Christi Bay, Texas, U.S.A. A 20-year record of randomized stations was used to determine the trend of surface water DO, salinity, and temperature over space and time. A 13-year record of two fixed stations was used to determine the temporal nutrient trends. A 10-year record of fixed stations in the southeastern region of Corpus Christi Bay was used to determine the status of disturbance caused by low DO in bottom waters. From 1982 to 2002, there was a significant decrease in surface water DO at a rate of 0.06 mg L(-1) yr(-1) and a significant increase in surface water temperature at a rate of 0.07 degrees C yr(-1). The southeastern region of Corpus Christi Bay had the lowest average DO, and during July and August, DO are steadily declining at a rate of 0.09 mg L(-1) yr(-1). It is not likely that eutrophication is causing hypoxia, because freshwater inflow rates have significantly decreased since 1941 and nutrient levels have not changed from 1987 to 2000. Even though long-term trends indicate that average surface DO is decreasing, disturbance by hypoxia appears to be stable, but this may be due to just eight years of data. In fact, if the current trend continues, surface water DO will not meet exceptional aquatic life standards (< or = 5 mg L(-1)) in 2032.

Dopaminergic neurotoxicity of S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, and S-methyl-N,N-diethylthiocarbamate (MeDETC) in Caenorhabditis elegans

PubMed Central

Caito, Samuel W.; Valentine, William M.; Aschner, Michael

2013-01-01

Epidemiological studies corroborate a correlation between pesticide use and Parkinson’s disease (PD). Thiocarbamate and dithiocarbamate pesticides are widely used and produce neurotoxicity in the peripheral nervous system. Recent evidence from rodent studies suggests that these compounds also cause dopaminergic (DAergic) dysfunction and altered protein processing, two hallmarks of PD. However, DAergic neurotoxicity has yet to be documented. We assessed DAergic dysfunction in Caenorhabditis elegans (C. elegans) to investigate the ability of thiocarbamate pesticides to induce DAergic neurodegeneration. Acute treatment with either S-ethyl N,N-dipropylthiocarbamate (EPTC), molinate, or a common reactive intermediate of dithiocarbamate and thiocarbamate metabolism, S-methyl-N,N-diethylthiocarbamate (MeDETC), to gradual loss of DAergic cell morphology and structure over the course of 6 days in worms expressing green fluorescent protein (GFP) under a DAergic cell specific promoter. HPLC analysis revealed decreased DA content in the worms immediately following exposure to MeDETC, EPTC, and molinate. Additionally, worms treated with the three test compounds showed a drastic loss of DAergic-dependent behavior over a time course similar to changes in DAergic cell morphology. Alterations in the DAergic system were specific, as loss of cell structure and neurotransmitter content was not observed in cholinergic, glutamatergic, or GABAergic systems. Overall, our data suggest that thiocarbamate pesticides promote neurodegeneration and DAergic cell dysfunction in C. elegans, and may be an environmental risk factor for PD. PMID:23786526

Decomposition of S-nitrosocysteine via S- to N-transnitrosation

PubMed Central

Peterson, Lisa A.; Wagener, Tanja; Sies, Helmut; Stahl, Wilhelm

2008-01-01

S-Nitrosothiols are thought to be important intermediates in nitric oxide signaling pathways. These compounds are unstable, in part, through their ability to donate NO. One model S-nitrosothiol, S-nitrosocysteine is particularly unstable. Recently, it was proposed that this compound decomposed via intra- and intermolecular transfer of the NO group from the sulfur to the nitrogen to form N-nitrosocysteine. This primary nitrosamine is expected to rapidly rearrange to ultimately form a reactive diazonium ion intermediate. To test this hypothesis, we demonstrated that thiirane-2-carboxylic acid is formed during the decomposition of S-nitrosocysteine at neutral pH. Acrylic acid was another product of this reaction. These results indicate that a small but significant amount of S-nitrosocysteine decomposes via S- to N-transnitrosation. The formation of a reactive intermediate in this process indicates the potential for this reaction to contribute to the toxicological properties of nitric oxide. PMID:17439249

Rhenium(V) Oxo Complexes of Novel N(2)S(2) Dithiourea (DTU) Chelate Ligands: Synthesis and Structural Characterization.

PubMed

Lipowska, Malgorzata; Hayes, Brittany L.; Hansen, Lory; Taylor, Andrew; Marzilli, Luigi G.

1996-07-03

The compounds RNHC(=S)NH(CH(2))(n)()NHC(=S)NHR were prepared in a search for new, relatively small N(2)S(2) ligands. These dithiourea (DTU) ligands are the first chelates containing two potentially bidentate thiourea moieties. A one-step reaction of 1,3-diaminopropane (1) with aryl or alkyl isothiocyanates or of 1,2-diaminoethane (2) with phenyl isothiocyanate afforded the target ligands in excellent yields (95-98%). The Re(V)=O complexes of RNHC(=S)NH(CH(2))(3)NHC(=S)NHR ligands were obtained through ligand exchange reactions with Re(V) precursors. The chemistry required neither protection of the sulfur atoms for ligand synthesis nor deprotection prior to metal complexation. The structure of (1-phenyl-3-(3-phenylthioureido)propyl]thioureato)oxorhenium(V) (7a), determined by X-ray diffraction methods, revealed the expected pseudo-square-pyramidal geometry with an N(2)S(2) basal and an apical oxo donor set. Both coordinated N's (N(c)) were deprotonated. One uncoordinated N (N(u)) was deprotonated, producing a neutral complex containing an unexpected new type of dianionic, four-membered N,S chelate. In the crystal, the N(u) atoms, N(3)H and N(4), of one complex each formed an H-bond with N(4) and N(3)H, respectively, of a symmetry-related complex. The N(c)-C-S bond angles (106.1(6) and 101.5(6) degrees ) were severely distorted from the 120 degrees expected for an sp(2)-hybridized C. However, these small bite angles and the large N-Re-N bond angle (86.1(3) degrees ) allowed for the formation of two four-membered chelate rings with normal Re-N and Re-S bond distances. Attempts to prepare complexes with the PhNHC(=S)NH(CH(2))(2)NHC(=S)NHPh ligand were unsuccessful. These results suggest that a central five-membered chelate ring is too small to accommodate bidentate coordination of both thiourea moieties. NMR studies in methanol established that the neutral complex with one uncoordinated N deprotonated was the favored form in neutral and basic solutions. However, under

Usefulness of Maintaining a Normal Electrocardiogram Over Time for Predicting Cardiovascular Health.

PubMed

Soliman, Elsayed Z; Zhang, Zhu-Ming; Chen, Lin Y; Tereshchenko, Larisa G; Arking, Dan; Alonso, Alvaro

2017-01-15

We hypothesized that maintaining a normal electrocardiogram (ECG) status over time is associated with low cardiovascular (CV) disease in a dose-response fashion and subsequently could be used to monitor programs aimed at promoting CV health. This analysis included 4,856 CV disease-free participants from the Atherosclerosis Risk in Communities study who had a normal ECG at baseline (1987 to 1989) and complete electrocardiographic data in subsequent 3 visits (1990 to 1992, 1993 to 1995, and 1996 to 1998). Participants were classified based on maintaining their normal ECG status during these 4 visits into "maintained," "not maintained," or "inconsistent" normal ECG status as defined by the Minnesota ECG classification. CV disease events (coronary heart disease, heart failure, and stroke) were adjudicated from Atherosclerosis Risk in Communities visit-4 through 2010. Over a median follow-up of 13.2 years, 885 CV disease events occurred. The incidence rate of CV disease events was lowest among study participants who maintained a normal ECG status, followed by those with an inconsistent pattern, and then those who did not maintain their normal ECG status (trend p value <0.001). Similarly, the greater the number of visits with a normal ECG status, the lower was the incidence rate of CV disease events (trend p value <0.001). Maintaining (vs not maintaining) a normal ECG status was associated with a lower risk of CV disease, which was lower than that observed in those with inconsistent normal ECG pattern (trend p value <0.01). In conclusion, maintaining a normal ECG status over time is associated with low risk of CV disease in a dose-response fashion, suggesting its potential use as a monitoring tool for programs promoting CV health. Copyright © 2016 Elsevier Inc. All rights reserved.

Leadership Matters: Prime Minister Koizumi’s Role in the Normalization of Japan’s Post-9/11 Security Policy

DTIC Science & Technology

2008-12-01

normalization of Japan’s post-9/11 security policy and discuss why it took his specific brand of leadership to allow Japan’s security policy to...security policy and discuss why it took his specific brand of leadership to allow Japan’s security policy to expand. vi THIS PAGE INTENTIONALLY LEFT...performance will demonstrate that institutional reasons alone will not make the position of prime minister stronger or more effective . The literature

Stratospheric ozone profile and total ozone trends derived from the SAGE I and SAGE II data

NASA Technical Reports Server (NTRS)

Mccormick, M. P.; Veiga, Robert E.; Chu, William P.

1992-01-01

Global trends in both stratospheric column ozone and as a function of altitude are derived on the basis of SAGE I/II ozone data from the period 1979-1991. A statistical model containing quasi-biennial, seasonal, and semiannual oscillations, a linear component, and a first-order autoregressive noise process was fit to the time series of SAGE I/II monthly zonal mean data. The linear trend in column ozone above 17-km altitude, averaged between 65 deg S and 65 deg N, is -0.30 +/-0.19 percent/yr, or -3.6 percent over the time period February 1979 through April 1991. The data show that the column trend above 17 km is nearly zero in the tropics and increases towards the high latitudes with values of -0.6 percent/yr at 60 deg S and -0.35 percent/yr at 60 deg N. Both these results are in agreement with the recent TOMS results. The profile trend analyses show that the column ozone losses are occurring below 25 km, with most of the loss coming from the region between 17 and 20 km. Negative trend values on the order of -2 percent/yr are found at 17 km in midlatitudes.

Analysis of trends of water quality and streamflow in the Blackstone, Branch, Pawtuxet, and Pawcatuck Rivers, Massachusetts and Rhode Island, 1979 to 2015

USGS Publications Warehouse

Savoie, Jennifer G.; Mullaney, John R.; Bent, Gardner C.

2017-02-21

Trends in long-term water-quality and streamflow data from six water-quality-monitoring stations within three major river basins in Massachusetts and Rhode Island that flow into Narragansett Bay and Little Narragansett Bay were evaluated for water years 1979–2015. In this study, conducted by the U.S. Geological Survey in cooperation with the Rhode Island Department of Environmental Management, the Rhode Island Water Resources Board, and the U.S. Environmental Protection Agency, water-quality and streamflow data were evaluated with a Weighted Regressions on Time, Discharge, and Season smoothing method, which removes the effects of year-to-year variation in water-quality conditions due to variations in streamflow (discharge). Trends in annual mean, annual median, annual maximum, and annual 7-day minimum flows at four continuous streamgages were evaluated by using a time-series smoothing method for water years 1979–2015.Water quality at all monitoring stations changed over the study period. Decreasing trends in flow-normalized nutrient concentrations and loads were observed during the period at most monitoring stations for total nitrogen, nitrite plus nitrate, and total phosphorus. Average flow-normalized loads for water years 1979–2015 decreased in the Blackstone River by up to 46 percent in total nitrogen, 17 percent in nitrite plus nitrate, and 69 percent in total phosphorus. The other rivers also had decreasing flow-normalized trends in nutrient concentrations and loads, except for the Pawtuxet River, which had an increasing trend in nitrite plus nitrate. Increasing trends in flow-normalized chloride concentrations and loads were observed during the study period at all of the rivers, with increases of more than 200 percent in the Blackstone River.Small increasing trends in annual mean daily streamflow were observed in 3 of the 4 rivers, with increases of 1.2 to 11 percent; however, the trends were not significant. All 4 rivers had decreases in streamflow for

Trends in state/territorial obesity prevalence by race/ethnicity among U.S. low-income, preschool-aged children.

PubMed

Pan, L; Grummer-Strawn, L M; McGuire, L C; Park, S; Blanck, H M

2016-10-01

Understanding state/territorial trends in obesity by race/ethnicity helps focus resources on populations at risk. This study aimed to examine trends in obesity prevalence among low-income, preschool-aged children from 2008 through 2011 in U.S. states and territories by race/ethnicity. We used measured weight and height records of 11.1 million children aged 2-4 years who participated in federally funded health and nutrition programmes in 40 states, the District of Columbia and two U.S. territories. We used logistic regression to examine obesity prevalence trends, controlling for age and sex. From 2008 through 2011, the aggregated obesity prevalence declined among all racial/ethnic groups (decreased by 0.4-0.9%) except American Indians/Alaska Natives (AI/ANs); the largest decrease was among Asians/Pacific Islanders (A/PIs). Declines were significant among non-Hispanic whites in 14 states, non-Hispanic blacks in seven states/territories, Hispanics in 13 states, A/PIs in five states and AI/ANs in one state. Increases were significant among non-Hispanic whites in four states, non-Hispanic blacks in three states, Hispanics in two states and A/PIs in one state. The majority of the states/territories had no change in obesity prevalence. Our findings indicate slight reductions in obesity prevalence and variations in obesity trends, but disparities exist for some states and racial/ethnic groups. © 2015 World Obesity.

Assessing Google Flu Trends Performance in the United States during the 2009 Influenza Virus A (H1N1) Pandemic

PubMed Central

Cook, Samantha; Conrad, Corrie; Fowlkes, Ashley L.; Mohebbi, Matthew H.

2011-01-01

Background Google Flu Trends (GFT) uses anonymized, aggregated internet search activity to provide near-real time estimates of influenza activity. GFT estimates have shown a strong correlation with official influenza surveillance data. The 2009 influenza virus A (H1N1) pandemic [pH1N1] provided the first opportunity to evaluate GFT during a non-seasonal influenza outbreak. In September 2009, an updated United States GFT model was developed using data from the beginning of pH1N1. Methodology/Principal Findings We evaluated the accuracy of each U.S. GFT model by comparing weekly estimates of ILI (influenza-like illness) activity with the U.S. Outpatient Influenza-like Illness Surveillance Network (ILINet). For each GFT model we calculated the correlation and RMSE (root mean square error) between model estimates and ILINet for four time periods: pre-H1N1, Summer H1N1, Winter H1N1, and H1N1 overall (Mar 2009–Dec 2009). We also compared the number of queries, query volume, and types of queries (e.g., influenza symptoms, influenza complications) in each model. Both models' estimates were highly correlated with ILINet pre-H1N1 and over the entire surveillance period, although the original model underestimated the magnitude of ILI activity during pH1N1. The updated model was more correlated with ILINet than the original model during Summer H1N1 (r = 0.95 and 0.29, respectively). The updated model included more search query terms than the original model, with more queries directly related to influenza infection, whereas the original model contained more queries related to influenza complications. Conclusions Internet search behavior changed during pH1N1, particularly in the categories “influenza complications” and “term for influenza.” The complications associated with pH1N1, the fact that pH1N1 began in the summer rather than winter, and changes in health-seeking behavior each may have played a part. Both GFT models performed well prior to and during pH1N1

Activation Strain Analysis of SN2 Reactions at C, N, O, and F Centers.

PubMed

Kubelka, Jan; Bickelhaupt, F Matthias

2017-02-02

Fundamental principles that determine chemical reactivity and reaction mechanisms are the very foundation of chemistry and many related fields of science. Bimolecular nucleophilic substitutions (S N 2) are among the most common and therefore most important reaction types. In this report, we examine the trends in the S N 2 reactions with respect to increasing electronegativity of the reaction center by comparing the well-studied backside S N 2 Cl - + CH 3 Cl with similar Cl - substitutions on the isoelectronic series with the second period elements N, O, and F in place of C. Relativistic (ZORA) DFT calculations are used to construct the gas phase reaction potential energy surfaces (PES), and activation strain analysis, which allows decomposition of the PES into the geometrical strain and interaction energy, is employed to analyze the observed trends. We find that S N 2@N and S N 2@O have similar PES to the prototypical S N 2@C, with the well-defined reaction complex (RC) local minima and a central barrier, but all stationary points are, respectively, increasingly stable in energy. The S N 2@F, by contrast, exhibits only a single-well PES with no barrier. Using the activation strain model, we show that the trends are due to the interaction energy and originate mainly from the decreasing energy of the empty acceptor orbital (σ* A-Cl ) on the reaction center A in the order of C, N, O, and F. The decreasing steric congestion around the central atom is also a likely contributor to this trend. Additional decomposition of the interaction energy using Kohn-Sham molecular orbital (KS-MO) theory provides further support for this explanation, as well as suggesting electrostatic energy as the primary reason for the distinct single-well PES profile for the FCl reaction.

Trends Plus: U.S. Medical School Applicants, Matriculants, Graduates 1992.

ERIC Educational Resources Information Center

Association of American Medical Colleges, Washington, DC.

This report provides statistical data and charts concerning trends in undergraduate medical education over the past decade. It presents trends in grade point averages (GPAs); in Medical College Admission Test (MCAT) scores for premedical school applicants and matriculants; and provides information on applicant and matriculant characteristics,…

Shuttling of nickel oxidation states in N4S2 coordination geometry versus donor strength of tridentate N2S donor ligands.

PubMed

Chatterjee, Sudip K; Roy, Suprakash; Barman, Suman Kumar; Maji, Ram Chandra; Olmstead, Marilyn M; Patra, Apurba K

2012-07-16

Seven bis-Ni(II) complexes of a N(2)S donor set ligand have been synthesized and examined for their ability to stabilize Ni(0), Ni(I), Ni(II) and Ni(III) oxidation states. Compounds 1-5 consist of modifications of the pyridine ring of the tridentate Schiff base ligand, 2-pyridyl-N-(2'-methylthiophenyl)methyleneimine ((X)L1), where X = 6-H, 6-Me, 6-p-ClPh, 6-Br, 5-Br; compound 6 is the reduced amine form (L2); compound 7 is the amide analog (L3). The compounds are perchlorate salts except for 7, which is neutral. Complexes 1 and 3-7 have been structurally characterized. Their coordination geometry is distorted octahedral. In the case of 6, the tridentate ligand coordinates in a facial manner, whereas the remaining complexes display meridional coordination. Due to substitution of the pyridine ring of (X)L1, the Ni-N(py) distances for 1~5 < 3 < 4 increase and UV-vis λ(max) values corresponding to the (3)A(2g)(F)→(3)T(2g)(F) transition show an increasing trend 1~5 < 2 < 3 < 4. Cyclic voltammetry of 1-5 reveals two quasi-reversible reduction waves that correspond to Ni(II)→Ni(I) and Ni(I)→Ni(0) reduction. The E(1/2) for the Ni(II)/Ni(I) couple decreases as 1 > 2 > 3 > 4. Replacement of the central imine N donor in 1 by amine 6 or amide 7 N donors reveals that complex 6 in CH(3)CN exhibits an irreversible reductive response at E(pc) = -1.28 V, E(pa) = +0.25 V vs saturated calomel electrode (SCE). In contrast, complex 7 shows a reversible oxidation wave at E(1/2) = +0.84 V (ΔE(p) = 60 mV) that corresponds to Ni(II)→Ni(III). The electrochemically generated Ni(III) species, [(L3)(2)Ni(III)](+) is stable, showing a new UV-vis band at 470 nm. EPR measurements have also been carried out.

Spectral and Photophysical Behavior of Cytisine in n-Hexane. Experimental Evidence for the S1(n,π*) → S0 Fluorescence.

PubMed

Krystkowiak, Ewa; Przybył, Anna K; Bayda, Małgorzata; Józkowiak, Julia; Maciejewski, Andrzej

2017-08-03

Spectral and photophysical properties of (-)-cytisine (the compound used as a smoking cessation aid and a potential drug in Alzheimer's and Parkinson's diseases) were investigated. The two conformers of cytisine, whose presence in the S 0 state has been earlier proved by the NMR and IR methods as well as in theoretical calculation, in nonpolar n-hexane show a rarely observed prompt fluorescence from the S 1 (n,π*) excited state. This observation is unambiguously evidenced by very small radiative rate constants of these two emitting conformers, k F = 7.4 × 10 5 and 3.0 × 10 5 s -1 . Their lifetimes in the S 1 (n,π*) state are relatively long, τ S 1 = 1.9 and 6.7 ns; therefore, their fluorescence quantum yield is relatively high ϕ F ∼ 10 -3 . The long-wavelength band in the cytisine absorption originates from the excitation to the S 2 (π,π*) state, while the S 1 (n,π*) state is not observed in this spectrum. Thus, the excited state S 2 (π,π*) is manifested only in the absorption spectrum, while the excited state S 1 (n,π*) is seen only in the fluorescence spectrum, so cytisine in n-hexane is characterized by close lying (n,π*) and (π,π*) excited singlet states.

Relationship between Trends in Land Precipitation and Tropical SST Gradient

NASA Technical Reports Server (NTRS)

Chung, Chul Eddy; Ramanathan, V.

2007-01-01

In this study, we examined global zonal/annual mean precipitation trends. Land precipitation trend from 1951 to 2002 shows widespread drying between 10 S to 20 N but the trend from 1977 to 2002 shows partial recovery. Based on general circulation model sensitivity studies, we suggested that these features are driven largely by the meridional SST gradient trend in the tropics. Our idealized CCM3 experiments substantiated that land precipitation is more sensitive to meridional SST gradient than to an overall tropical warming. Various simulations produced for the IPCC 4th assessment report demonstrate that increasing CO2 increases SST in the entire tropics non-uniformly and increases land precipitation only in certain latitude belts, again pointing to the importance of SST gradient change. Temporally varying aerosols in the IPCC simulations alter meridional SST gradient and land precipitation substantially. Anthropogenic aerosol direct solar forcing without its effects on SST is shown by the CCM3 to have weak but non-negligible influence on land precipitation.

Calculations of long-range three-body interactions for He(n0λS )-He(n0λS )-He(n0'λL )

NASA Astrophysics Data System (ADS)

Yan, Pei-Gen; Tang, Li-Yan; Yan, Zong-Chao; Babb, James F.

2018-04-01

We theoretically investigate long-range interactions between an excited L -state He atom and two identical S -state He atoms for the cases of the three atoms all in spin-singlet states or all in spin-triplet states, denoted by He(n0λS )-He(n0λS )-He(n0'λL ), with n0 and n0' principal quantum numbers, λ =1 or 3 the spin multiplicity, and L the orbital angular momentum of a He atom. Using degenerate perturbation theory for the energies up to second-order, we evaluate the coefficients C3 of the first-order dipolar interactions and the coefficients C6 and C8 of the second-order additive and nonadditive interactions. Both the dipolar and dispersion interaction coefficients, for these three-body degenerate systems, show dependences on the geometrical configurations of the three atoms. The nonadditive interactions start to appear in second-order. To demonstrate the results and for applications, the obtained coefficients Cn are evaluated with highly accurate variationally generated nonrelativistic wave functions in Hylleraas coordinates for He(1 1S ) -He(1 1S ) -He(2 1S ) , He(1 1S ) -He(1 1S ) -He(2 1P ) , He(2 1S ) -He(2 1S ) -He(2 1P ) , and He(2 3S ) -He(2 3S ) -He(2 3P ) . The calculations are given for three like nuclei for the cases of hypothetical infinite mass He nuclei, and of real finite mass 4He or 3He nuclei. The special cases of the three atoms in equilateral triangle configurations are explored in detail, and for the cases in which one of the atoms is in a P state, we also present results for the atoms in an isosceles right triangle configuration or in an equally spaced collinear configuration. The results can be applied to construct potential energy surfaces for three helium atom systems.

A N-S fossil transform fault reactivated by the March 2, 2016 Mw7.8 southwest of Sumatra, Indonesia earthquake

NASA Astrophysics Data System (ADS)

Zhang, H.; van der Lee, S.

2016-12-01

Warton Basin (WB) is characterized by N-S striking fossil transform faults and E-W trending extinct ridges. The 2016 Mw7.8 southwest of Sumatra earthquake, nearby the WB's center, was first imaged by back-projecting P-waves from three regional seismic networks in Europn, Japan, and Australia. Next, the rupture direction of the earthquake was further determined using the rupture directivity analysis to P-waves from the global seismic network (GSN). Finally, we inverting these GSN waveforms on a defined N-S striking vertical fault for a kinematic source model. The results show that the earthquake reactivates a 190 degree N-S striking vertical fossil transform fault and asymmetrically bilaterally ruptures a 65 km by 30 km asperity over 35 s. Specifically, the earthquake first bilaterally ruptures northward and southward at a speed of 1.0 km/s over the first 12 s, and then mainly rupture northward at a speed of 1.6 km/s. Compared with two previous M≥7.8 WB earthquakes, including the 2000 southern WB earthquake and 2012 Mw8.6 Sumatra earthquake, the lower seismic energy radiation efficiency and slower rupture velicity of the 2016 earthquake indicate the rupture of the earthquake is probably controlled by the warmer ambient slab and tectonic stress regime.

Education and Income: Recent U.S. Trends.

ERIC Educational Resources Information Center

Levy, Frank; Michel, Richard C.

This paper examines the growing college premium for younger men and the earnings patterns for other groups that developed between 1973 and 1987. At first glance, the rapidly increasing college premium for young men seems to confirm several frequently cited economic trends, including a massive restructuring of the economy that displaces all less…

Dissociative Functions in the Normal Mourning Process.

ERIC Educational Resources Information Center

Kauffman, Jeffrey

1994-01-01

Sees dissociative functions in mourning process as occurring in conjunction with integrative trends. Considers initial shock reaction in mourning as model of normal dissociation in mourning process. Dissociation is understood to be related to traumatic significance of death in human consciousness. Discerns four psychological categories of…

What is normal in normal aging? Effects of Aging, Amyloid and Alzheimer’s Disease on the Cerebral Cortex and the Hippocampus

PubMed Central

Fjell, Anders M.; McEvoy, Linda; Holland, Dominic; Dale, Anders M.; Walhovd, Kristine B

2015-01-01

What can be expected in normal aging, and where does normal aging stop and pathological neurodegeneration begin? With the slow progression of age-related dementias such as Alzheimer’s Disease (AD), it is difficult to distinguish age-related changes from effects of undetected disease. We review recent research on changes of the cerebral cortex and the hippocampus in aging and the borders between normal aging and AD. We argue that prominent cortical reductions are evident in fronto-temporal regions in elderly even with low probability of AD, including regions overlapping the default mode network. Importantly, these regions show high levels of amyloid deposition in AD, and are both structurally and functionally vulnerable early in the disease. This normalcy-pathology homology is critical to understand, since aging itself is the major risk factor for sporadic AD. Thus, rather than necessarily reflecting early signs of disease, these changes may be part of normal aging, and may inform on why the aging brain is so much more susceptible to AD than is the younger brain. We suggest that regions characterized by a high degree of life-long plasticity are vulnerable to detrimental effects of normal aging, and that this age-vulnerability renders them more susceptible to additional, pathological AD-related changes. We conclude that it will be difficult to understand AD without understanding why it preferably affects older brains, and that we need a model that accounts for age-related changes in AD-vulnerable regions independently of AD-pathology. PMID:24548606

Trends in Non-Volcanic Stratospheric Aerosol Determined from 30 Years of Aerosol Measurements by Lidar and Balloon-borne Particle Counters

NASA Astrophysics Data System (ADS)

Deshler, T.; Anderson-Sprecher, R.; Jäger, H.; Barnes, J.; Hofmann, D.; Clemesha, B.; Simonich, D.

2005-05-01

Junge's initial stratospheric aerosol measurements (1959-1960), at the end of a long volcanically quiescent period, and the long term stratospheric aerosol measurements beginning in the 1970s have been investigated for trends in non-volcanic stratospheric aerosol. These investigations have focused on the inter-volcanic "background" periods, which until post Pinatubo, have been rather brief. Since 1959 there have been approximately 30 eruptions with volcanic explosivity indices of 4 or more. The five 30 year records of stratospheric aerosol are comprised of one in situ record [aerosol concentration for 0.15 and 0.25 um radius particles above Laramie, Wyoming, USA (1971-2003, 41N)] and four lidar records [S. J. dos Campos, Brazil (1972-2003, 23S), Mauna Loa, Hawaii, USA (1974-2003, 20N), Hampton, Virginia, USA (1974-2002, 37N), Garmisch-Partenkirchen, Germany (1976-2002, 48N)]. These data capture the three major aerosol-producing eruptions, Fuego, El Chichón and Pinatubo, as well as the three inter-volcanic background periods. These records form the basis for an assessment of the trend in background stratospheric aerosol. The quantities to be investigated are integral number concentrations and integrated backscatter above the tropopause. These records were analyzed following two approaches. First the 3 volcanically quiescent periods are compared using a standard analysis of variance approach. Second an empirical model is used to remove the volcanic signal from the long term records and then the residuals are investigated for trends. The model is a parametric exponential decay model, requiring 4 parameters for each volcano and 2 parameters for background. The optimization procedure uses a priori estimates for each parameter and then standard squared-error residual minimization to obtain the set of parameters providing the minimum in the residuals. The baseline and autocorrelated residuals are then investigated for trend. The results suggest that the trend in

Wet-bulb, dew point, and air temperature trends in Spain

NASA Astrophysics Data System (ADS)

Moratiel, R.; Soriano, B.; Centeno, A.; Spano, D.; Snyder, R. L.

2017-10-01

This study analyses trends of mean ( T m), maximum ( T x), minimum ( T n), dew point ( T d), and wet-bulb temperatures ( T w) on an annual, seasonal, and monthly time scale over Spain during the period 1981-2010. The main purpose was to determine how temperature and humidity changes are impacting on T w, which is probably a better measure of climate change than temperature alone. In this study, 43 weather stations were used to detect data trends using the nonparametric Mann-Kendall test and the Sen method to estimate the slope of trends. Significant linear trends observed for T m, T x, and T n versus year were 56, 58, and 47 % of the weather stations, respectively, with temperature ranges between 0.2 and 0.4 °C per decade. The months with bigger trends were April, May, June, and July with the highest trend for T x. The spatial behaviour of T d and T w was variable, with various locations showing trends from -0.6 to +0.3 °C per decade for T d and from -0.4 to +0.5 °C per decade for T w. Both T d and T w showed negative trends for July, August, September, November, and December. Comparing the trends versus time of each variable versus each of the other variables exhibited poor relationships, which means you cannot predict the trend of one variable from the trend of another variable. The trend of T x was not related to the trend of T n. The trends of T x, T m, and T n versus time were unrelated to the trends versus time of either T d or T w. The trend of T w showed a high coefficient of determination with the trend of T d with an annual value of R 2 = 0.86. Therefore, the T w trend is more related to changes in humidity than temperature.

New Jersey's Segregated Schools: Trends and Paths Forward

ERIC Educational Resources Information Center

Orfield, Gary; Ee, Jongyeon; Coughlan, Ryan

2017-01-01

This report updates earlier research published by the Civil Rights Project in 2013. That report detailed troubling racial and economic segregation trends and patterns from 1989-2010. The latest report includes new data from 2010-2015. The research updates public school enrollment trends and details segregation in the state's schools by race and…

Differentiation of isomeric N-glycan structures by normal-phase liquid chromatography-MALDI-TOF/TOF tandem mass spectrometry.

PubMed

Maslen, Sarah; Sadowski, Pawel; Adam, Alex; Lilley, Kathryn; Stephens, Elaine

2006-12-15

The detailed characterization of protein N-glycosylation is very demanding given the many different glycoforms and structural isomers that can exist on glycoproteins. Here we report a fast and sensitive method for the extensive structure elucidation of reducing-end labeled N-glycan mixtures using a combination of capillary normal-phase HPLC coupled off-line to matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) and TOF/TOF-MS/MS. Using this method, isobaric N-glycans released from honey bee phospholipase A2 and Arabidopsis thaliana glycoproteins were separated by normal-phase chromatography and subsequently identified by key fragment ions in the MALDI-TOF/TOF tandem mass spectra. In addition, linkage and branching information were provided by abundant cross-ring and "elimination" fragment ions in the MALDI-CID spectra that gave extensive structural information. Furthermore, the fragmentation characteristics of N-glycans reductively aminated with 2-aminobenzoic acid and 2-aminobenzamide were compared. The identification of N-glycans containing 3-linked core fucose was facilitated by distinctive ions present only in the MALDI-CID spectra of 2-aminobenzoic acid-labeled oligosaccharides. To our knowledge, this is the first MS/MS-based technique that allows confident identification of N-glycans containing 3-linked core fucose, which is a major allergenic determinant on insect and plant glycoproteins.

The end of trend-estimation for extreme floods under climate change?

NASA Astrophysics Data System (ADS)

Schulz, Karsten; Bernhardt, Matthias

2016-04-01

An increased risk of flood events is one of the major threats under future climate change conditions. Therefore, many recent studies have investigated trends in flood extreme occurences using historic long-term river discharge data as well as simulations from combined global/regional climate and hydrological models. Severe floods are relatively rare events and the robust estimation of their probability of occurrence requires long time series of data (6). Following a method outlined by the IPCC research community, trends in extreme floods are calculated based on the difference of discharge values exceeding e.g. a 100-year level (Q100) between two 30-year windows, which represents prevailing conditions in a reference and a future time period, respectively. Following this approach, we analysed multiple, synthetically derived 2,000-year trend-free, yearly maximum runoff data generated using three different extreme value distributions (EDV). The parameters were estimated from long term runoff data of four large European watersheds (Danube, Elbe, Rhine, Thames). Both, Q100-values estimated from 30-year moving windows, as well as the subsequently derived trends showed enormous variations with time: for example, estimating the Extreme Value (Gumbel) - distribution for the Danube data, trends of Q100 in the synthetic time-series range from -4,480 to 4,028 m³/s per 100 years (Q100 =10,071m³/s, for reference). Similar results were found when applying other extreme value distributions (Weibull, and log-Normal) to all of the watersheds considered. This variability or "background noise" of estimating trends in flood extremes makes it almost impossible to significantly distinguish any real trend in observed as well as modelled data when such an approach is applied. These uncertainties, even though known in principle are hardly addressed and discussed by the climate change impact community. Any decision making and flood risk management, including the dimensioning of flood

Normal Modes of a Lagrangian System Constrained in a Potential Well.

DTIC Science & Technology

1983-12-01

A’ -137 948 NORMAL MODES OF A LFHbRANGIAN SYSTEM CONSTRAINED INvi P0TENTIAL WELL(U WISCONSNN UNIV-MADISON MATHEMATICS RESEARCH CENTER V EN DEC F1...Carolina 27709 DT FLE OP Y UNIVERSITY OF WISCONSIN-MADISON MATHEMATICS RESEARCH CENTER NORMAL MODES OF A LAGRANGIAN SYSTEM CONSTRAINED IN A POTENTIAL WELL...respect to the norm lYE [f i + 2 yi )dtl/ 0 Since H I(S’ 1 n’) C CO(S, fle ), then the set A 1 0 is an open set in H1 (lf’) The periodic solution of

Trends in atmospheric heavy metals abundances over the Russian part of EMEP region in 1990-2012

NASA Astrophysics Data System (ADS)

Gromov, Sergey A.; Konkova, Elizaveta S.

2016-04-01

The European part of Russia is covered by two atmospheric environment monitoring networks established in the 1970s-1980s to monitor and evaluate anthropogenic pollution of regional/background natural environment. These are EMEP - European Monitoring and Evaluation Program of transboundary atmospheric pollutant transmission (under the UN ECE Convention on Long-Range Transboundary Air Pollution) and IBMoN - Integrated Background Monitoring Network of environmental toxic pollution (prior to 1990 under the UNEP/GEMS supervision, mostly for East European countries). IGCE laboratories operate as analytical centers for both networks. Historically, IBMoN was partly implemented at EMEP sites to support this international program with additional (optional) data. IBMoN datasets were selected for analysis of atmospheric heavy metal trends in the Russian territory of EMEP region for the last twenty three years due to more intensive operation up to now [1, 2]. Atmospheric heavy metals are collected at the remote sites with the air samples of atmospheric aerosols deposited on Petryanov's cellulose acetate filters through high-volume pumping during 24 hours. To measure lead and cadmium content, filters are transferred into the solution to determine total amounts by the Atomic Absorption Spectroscopy (AAS) with flameless atomization. Precipitation samples (collected monthly with acidic preserving) are directly injected into the AAS detection module after filtering. The sampling procedure, special processing and analytical techniques allow us to measure concentrations at substantially low levels [3, 2]. In this study we investigate the long term trends of lead and cadmium in air and precipitation at two stations, viz. Astrakhan Biosphere Reserve (46°N, 49°E) and Danki (Oka-Terrace Biosphere Reserve, 54.9°N, 37.8°E). Following the EMEP general recommendations, the evaluation was done for two continuous periods covering 1990-2001 and 2002-2012, respectively. We apply the common

Connection between Dynamically Derived Initial Mass Function Normalization and Stellar Population Parameters

NASA Astrophysics Data System (ADS)

McDermid, Richard M.; Cappellari, Michele; Alatalo, Katherine; Bayet, Estelle; Blitz, Leo; Bois, Maxime; Bournaud, Frédéric; Bureau, Martin; Crocker, Alison F.; Davies, Roger L.; Davis, Timothy A.; de Zeeuw, P. T.; Duc, Pierre-Alain; Emsellem, Eric; Khochfar, Sadegh; Krajnović, Davor; Kuntschner, Harald; Morganti, Raffaella; Naab, Thorsten; Oosterloo, Tom; Sarzi, Marc; Scott, Nicholas; Serra, Paolo; Weijmans, Anne-Marie; Young, Lisa M.

2014-09-01

We report on empirical trends between the dynamically determined stellar initial mass function (IMF) and stellar population properties for a complete, volume-limited sample of 260 early-type galaxies from the ATLAS3D project. We study trends between our dynamically derived IMF normalization αdyn ≡ (M/L)stars/(M/L)Salp and absorption line strengths, and interpret these via single stellar population-equivalent ages, abundance ratios (measured as [α/Fe]), and total metallicity, [Z/H]. We find that old and alpha-enhanced galaxies tend to have on average heavier (Salpeter-like) mass normalization of the IMF, but stellar population does not appear to be a good predictor of the IMF, with a large range of αdyn at a given population parameter. As a result, we find weak αdyn-[α/Fe] and αdyn -Age correlations and no significant αdyn -[Z/H] correlation. The observed trends appear significantly weaker than those reported in studies that measure the IMF normalization via the low-mass star demographics inferred through stellar spectral analysis.

Flow behaviour in normal and Meniere’s disease of endolymphatic fluid inside the inner ear

NASA Astrophysics Data System (ADS)

Paisal, Muhammad Sufyan Amir; Azmi Wahab, Muhamad; Taib, Ishkrizat; Mat Isa, Norasikin; Ramli, Yahaya; Seri, Suzairin Md; Darlis, Nofrizalidris; Osman, Kahar; Khudzari, Ahmad Zahran Md; Nordin, Normayati

2017-09-01

Meniere’s disease is a rare disorder that affects the inner ear which might be more severe if not treated. This is due to fluctuating pressure of the fluid in the endolymphatic sac and dysfunction of cochlea which causing the stretching of vestibular membrane. However, the pattern of the flow recirculation in endolymphatic region is still not fully understood. Thus, this study aims to investigate the correlation between the increasing volume of endolymphatic fluid and flow characteristics such as velocity, pressure and wall shear stress. Three dimensional model of simplified endolymphatic region is modeled using computer aided design (CAD) software and simulated using computational fluid dynamic (CFD) software. There are three different models are investigated; normal (N) model, Meniere’s disease model with less severity (M1) and Meniere’s disease model with high severity (M2). From the observed, the pressure drop between inlet and outlet of inner ear becomes decreases as the outlet pressure along with endolymphatic volume increases. However, constant flow rate imposed at the inlet of endolymphatic showing the lowest velocity. Flow recirculation near to endolymphatic region is occurred as the volume in endolympathic increases. Overall, high velocity is monitored near to cochlear duct, ductus reuniens and endolymphatic duct. Hence, these areas show high distributions of wall shear stress (WSS) that indicating a high probability of endolymphatic wall membrane dilation. Thus, more severe conditions of Meniere’s disease, more complex of flow characteristic is occurred. This phenomenon presenting high probability of rupture is predicted at the certain area in the anatomy of vestibular system.

Trends in der IT-Sicherheit

NASA Astrophysics Data System (ADS)

Eckert, Claudia

Ich möchte Ihnen einen Überblick geben über Trends, Challenges, offene Fragestellungen sowie Lösungsansätze aus dem Bereich der IT-Sicherheit. Meine Vorredner haben mir schon eine wunderbare Basis dafür geschaffen, indem sie wichtige Trends im Bereich IT bereits angesprochen haben. Deshalb werde ich auf diese Trends, nämlich das Internet of Things and Services nur noch einmal kurz eingehen, um daran dann die IT-Sicherheitsthemen, die sich aus diesen IT-Trends ergeben, zu skizzieren und anschließend Lösungen vorstellen, die insbesondere im Forschungsumfeld entwickelt werden, aber schon reif sind, auch in die unternehmerische Praxis übernommen zu werden.

U.S. Energy Service Company (ESCO) Industry: Recent Market Trends

DOE Office of Scientific and Technical Information (OSTI.GOV)

Stuart, Elizabeth; Larsen, Peter H.; Carvallo, Juan Pablo

This study presents an analysis of the market size, growth projections and industry trends of the U.S. Energy Service Company (ESCO) industry, drawing on information provided by ESCO executives in late 2015. We define ESCOs as energy service companies for whom performance-based contracting is a core business offering. We identified forty-seven firms that met our definition of an ESCO.1 Forty-three of these companies responded to our requests for information, representing a 91% response rate.2 We also report 2014 ESCO industry revenues by market segment, region and business activity type, and for new versus existing customers. Finally, we report on usemore » of tax incentives and financing tools, and incorporation of non-energy benefits into performance-based project economics. We summarize key findings below.« less

Upper-normal waist circumference is a risk marker for metabolic syndrome in normal-weight subjects.

PubMed

Okada, R; Yasuda, Y; Tsushita, K; Wakai, K; Hamajima, N; Matsuo, S

2016-01-01

To elucidate implication of upper-normal waist circumference (WC), we examined whether the normal range of WC still represents a risk of metabolic syndrome (MetS) or non-adipose MetS components among normal-weight subjects. A total of 173,510 persons (100,386 men and 73,124 women) with normal WC (<90/80 cm in men/women) and body mass index (BMI) of 18.5-24.9 were included. Subjects were categorized as having low, moderate, and upper-normal WC for those with WC < 80, 80-84, and 85-89 cm in men and <70, 70-74, and 75-79 cm in women, respectively. The prevalence of all the non-adipose MetS components (e.g. prediabetes and borderline dyslipidemia) was significantly higher in subjects with upper-normal WC on comparison with those with low WC. Overall, the prevalence of MetS (having three or more of four non-adipose MetS components) gradually increased with increasing WC (12%, 21%, and 27% in men and 11%, 14%, and 19% in women for low, moderate, and upper-normal WC, respectively). Moreover, the risk of having a greater number of MetS components increased in subjects with upper-normal WC compared with those with low WC (odds ratios for the number of one, two, three, and four MetS components: 1.29, 1.81, 2.53, and 2.47 in men and 1.16, 1.55, 1.49, and 2.20 in women, respectively). Upper-normal WC represents a risk for acquiring a greater number of MetS components and the early stage of MetS components (prediabetes and borderline dyslipidemia), after adjusting for BMI, in a large general population with normal WC and BMI. Copyright © 2015 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

North Atlantic cyclones; trends, impacts and links to large-scale variability

NASA Astrophysics Data System (ADS)

Trigo, R. M.; Trigo, I. F.; Ramos, A. M.; Paredes, D.; Garcia-Herrera, R.; Liberato, M. L. R.; Valente, M. A.

2009-04-01

Based on the cyclone detection and tracking algorithm previously developed (Trigo, 2006) we have assessed the inter-annual variability and cyclone frequency trends between 1960 and 2000 for the Euro-Atlantic sector using the highest spatial resolution available (1.125° x 1.125°) from the ERA-40 Surface Level Pressure. Additionally, trends for the u and v wind speed components are also computed at the monthly and seasonal scales, using the same dataset. All cyclone and wind speed trend maps were computed with the corresponding statistical significance field. Results reveal a significant frequency decrease (increase) in the western Mediterranean (Greenland and Scandinavia), particularly in December, February and March. Seasonal and monthly analysis of wind speed trends shows similar spatial patterns. We show that these changes in the frequency of low pressure centers and the associated wind patterns are partially responsible for trends of the significant height of waves. Throughout the extended winter months (ONDJFM), regions with positive (negative) wind magnitude trends, of up to 5 cm/s per year, often correspond to regions of positive (negative) significant wave height trends. The cyclone and wind speed trends computed for the JFM months are well matched by the corresponding trends in significant wave height, with February being the month with the highest trends (negative south of 50°N up to -3 cm/year, and positive up to 5cm/year just north of Scotland). Using precipitation data from ECMWF reanalyses and a CRU high resolution dataset we show the impact of these trends in cyclone frequencies upon the corresponding precipitation trends in the influenced areas. It is also shown that these changes are partially linked to major shifts on the indices of large-scale patterns modes, namely the North Atlantic Oscillation (NAO), the Eastern Atlantic (EA) and the Scandinavian Patterns (SCAN). Trigo, I. F. 2006: Climatology and Interannual Variability of Storm-Tracks in

Trends in U.S. Venture Capital Investments Related to Energy: 1980-2007

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dooley, James J.

This report documents trends in U.S. venture capital investments over the period 1980-2008. Particular attention is given to U.S. venture capital investments for “internet-specific”, biotechnology, and energy / industrial sectors over the period 1980-2007. During the early 1980s, U.S. venture capital investments in the energy / industrial area accounted for more than 20% of all venture capital investments. However subsequent periods of low energy prices and the emergence of fast growing new industries like computers (both hardware and software), biotechnology and the Internet quickly reduced the priority accorded to energy / industrial investments as by 2000 these investments accounted formore » only 1% of the $119 billion dollars invested that year by the U.S. venture capital community. The significant increase in the real price of oil that began in 2003-2004 correlates with renewed interest and increased investment by the venture capital community in energy / industrial investment opportunities. Venture capital investments in 2007 for the energy / industrial sector accounted for $3 billion or slightly more than 10% of all venture capital invested that year.« less

Trends in the size distribution, highway use, and consumption of gasoline and diesel fuels of the U.S. Commercial Truck Fleet, 1977-2002.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bertram, K. M.; Santini, D. J.; Anderson, J. L.

2008-01-01

This paper focuses on various major long-range (1977-2002, 1982-2002) U.S. commercial trucking trends by using U.S. Department of Commerce, Bureau of the Census Vehicle/Truck Inventory and Use Survey (VIUS/TIUS) data from this period, as well as selected 1977-2002 data from the U.S. Department of Energy's (DOE's) Energy Information Administration (EIA) and the U.S. Department of Transportation, Federal Highway Administration's (FHWA's) Highway Statistics. Analyses are made of (1) overall passenger vehicle versus truck consumption patterns of gasoline and diesel fuel and (2) the population growth and fuels used by all commercial truck classes and selected truck types (single unit and combination).more » Selected vehicle miles traveled, gallons per vehicle miles traveled, and gallons per cargo ton-miles traveled trends, as well as the effect of cargo tons per truck on fuel consumption, are also assessed. In addition, long-range trends of related factors (such as long-haul mileages driven by heavy trucks) and their impacts on both reducing fuel consumption per cargo-ton-mile and the relative shares of total commercial fuel use among truck classes were examined. Results of these trends on U.S. petroleum consumption are identified. The effects of basic engineering design and performance, national Interstate highway construction legislation, national demographic trends (such as suburbanization), and changes in U.S. corporate operational requirements are discussed. Their impacts on both the long-distance hauling and shorter-distance urban and suburban delivery markets of the commercial trucking industry are highlighted.« less

Effects on U.S. Timber Outlook of Recent Economic Recession, Collapse in Housing Construction, and Wood Energy Trends

Treesearch

Peter J. Ince; Prakash Nepal

2012-01-01

This paper reviews recent trends and structural changes in U.S. forest product markets and projects their effects on the long-range U.S. timber market outlook. The analysis derives from the same U.S. and global economic model that produced 50-year projections for the 2010 RPA nationwide forest assessment, but analysis is revised to more accurately include the economic...

SLOCC classification of n qubits invoking the proportional relationships for spectrums and standard Jordan normal forms

NASA Astrophysics Data System (ADS)

Li, Dafa

2018-01-01

We investigate the proportional relationships for spectrums and standard Jordan normal forms (SJNFs) of the 4 by 4 matrices constructed from coefficient matrices of two SLOCC (stochastic local operations and classical communication) equivalent states of n qubits. The proportional relationships permit a reduction of SLOCC classification of n (≥ 4) qubits to a classification of 4 by 4 complex matrices. Invoking the proportional relationships for spectrums and SJNFs, pure states of n (≥ 4) qubits are partitioned into 12 groups or less and 34 families or less under SLOCC, respectively. Specially, it is true for four qubits.

Nitrate Trends in Minnesota Rivers

USGS Publications Warehouse

Wall, Dave; Christopherson, Dave; Lorenz, Dave; Martin, Gary

2013-01-01

The objective of this study was to assess long-term trends (30 to 35 years) of flow-adjusted concentrations of nitrite+nitrate-N (hereinafter referred to as nitrate) in a way that would allow us to discern changing trends. Recognizing that these trends are commonly different from one river to another river and from one part of the state to another, our objective was to examine as many river monitoring sites across the state as possible for which sufficient long term streamflow and concentration data were available.

Alcohol consumption trends in Australia: Comparing surveys and sales-based measures.

PubMed

Livingston, Michael; Callinan, Sarah; Raninen, Jonas; Pennay, Amy; Dietze, Paul M

2018-04-01

Survey data remain a crucial means for monitoring alcohol consumption, but there has been limited work done to ensure that surveys adequately capture changes in per-capita consumption in Australia. In this study, we explore how trends in consumption from two major Australian surveys compare with an official measure of per-capita consumption between 2001 and 2014 and examine age-specific trends in drinking. Data were from five waves of the cross-sectional National Health Survey (total n = 113 279) and 12 waves of the longitudinal Household Income and Labour Dynamics in Australia Study (average n = 12 347). Overall and age-specific estimates of annual alcohol consumption were derived and compared with official per-capita consumption and previous analyses of the National Drug Strategy Household Survey. In terms of overall consumption, both surveys broadly reflected trends in per-capita consumption, especially the decline that has been observed since 2007/2008. Age-specific trends were broadly similar, with the recent decline in consumption clearly concentrated among teenagers and young adults. The main Australian monitoring surveys remain useful monitoring tools for alcohol consumption in Australia. There is consistent evidence that the recent declines in Australian per-capita consumption have been driven by sharp falls in drinking among young people, a trend that requires further study. [Livingston M, Callinan S, Raninen J, Pennay A, Dietze PM. Alcohol consumption trends in Australia: Comparing surveys and sales-based measures. Drug Alcohol Rev 2017;00:000-000]. © 2017 Australasian Professional Society on Alcohol and other Drugs.

Trends in maternal and infant health in poor urban neighborhoods: good news from the 1990s, but challenges remain.

PubMed

Howell, Embry M; Pettit, Kathryn L S; Kingsley, G Thomas

2005-01-01

During the 1990s, numerous public policy changes occurred that may have affected the health of mothers and infants in low-income neighborhoods. This article examines trends in key maternal and child health indicators to determine whether disparities between high-poverty neighborhoods and other neighborhoods have declined. Using neighborhood-level vital statistics and U.S. Census data, we categorized "neighborhoods" (Census tracts) as being high poverty (greater than 30% of population below the federal poverty level in 1990) or not. We compared trends in four key indicators--births to teenagers, late prenatal care, low birth-weight; and infant mortality--over the 1990s among high-poverty and other neighborhoods in Cuyahoga County, Ohio; Denver, Colorado; Marion County, Indiana; and Oakland, California. In all four metropolitan areas, trends in high-poverty neighborhoods were more favorable than in other neighborhoods. The most consistently positive trend was the reduction in the rate of teen births. The metropolitan areas with the most intensive programs to improve maternal and child health--Cuyahoga County and Oakland-saw the most consistent improvement across all indicators. Still, great disparities between high-poverty and other neighborhoods remain, and only Oakland shows promise of achieving some of the Healthy People 2010 maternal and child health goals in its high-poverty neighborhoods. While there has been a reduction in maternal and infant health disparities between high-poverty and other neighborhoods, much work remains to eliminate disparities and achieve the 2010 goals. Small area data are useful in isolating the neighborhoods that should be targeted. Experience from the 1990s suggests that a combination of several intensive interventions can be effective at reducing disparities.

A U.S. Wind Climatology: new tools to monitor wind trends across the contiguous United States

NASA Astrophysics Data System (ADS)

Crouch, J.; Wallis, T. W.; Arndt, D.

2010-12-01

NOAA’s National Climatic Data Center has developed a new monthly and seasonal product to provide a spatially continuous wind climatology for the contiguous U.S. using NCEP reanalysis data. Surface wind observations are sparse over specific regions of the country, and are subject to many local effects. By utilizing the sigma .995 level of the reanalysis data we can monitor wind conditions and trends of the lower troposphere across the entire U.S. The wind data are interpolated from a 2.5 x 2.5 degree grid to 0.25 degrees to provide additional detail. Data are analyzed from January 1950 to the most current month. Monthly averaged winds and wind anomalies are calculated with respect to the 1971-2000 base period, and time series for each grid point show how regional winds have changed over the 60 year period of record. The goal of this new climatology product is to provide regional decision support for the emerging wind energy sector, in addition to others who are interested in the current state of wind conditions. The U.S. Department of Energy has outlined a plan for 20 percent of U.S. electricity production to be from wind by 2030, and having a temporally and spatially continuous wind dataset, updated on a monthly basis, will be beneficial to understanding wind trends nationwide.

Trends in pan evaporation and actual evapotranspiration across the conterminous U.S.: paradoxical or complementary?

Treesearch

Michael T. Hobbins; Jorge A. Ramirez; Thomas C. Brown

2004-01-01

Pan evaporation (ETpan) has decreased at 64% of pans in the conterminous U.S. over the past half-century. Comparing trends in ETpan and water budget-derived actual evapotranspiration (ET*a), we observe the so-called ‘‘Pan Evaporation Paradox,’’ which we confirm is no more than a...

Outdoor recreation activity trends by volume segments: U.S. and Northeast market analyses, 1982-1989

Treesearch

Rodney B. Warnick

1992-01-01

The purpose of this review was to examine volume segmentation within three selected outdoor recreational activities -- swimming, hunting and downhill skiing over an eight-year period, from 1982 through 1989 at the national level and within the Northeast Region of the U.S.; and to determine if trend patterns existed within any of these activities when the market size...

Formation of the thioester, N,S-diacetylcysteine, from acetaldehyde and N,N'-diacetylcystine in aqueous solution with ultraviolet light

NASA Technical Reports Server (NTRS)

Weber, A. L.

1981-01-01

The thioester, N,S-diacetylcysteine, is formed during the illumination of phosphate buffered (pH 7.0) aqueous solutions of acetaldehyde and N,N'-diacetylcystine with ultraviolet light. The yield of N,S-diacetylcysteine relative to N-acetylcysteine and unidentified products progressively increases as ultraviolet light below 239 nm, 253 nm and 281 nm is cut off with optical filters. When ultraviolet light below 320 nm is removed with an optical filter, there is no detectable reaction. Illumination of 0.025 M N,N'-diacetylcystine with 0.5 M and 1.0 M acetaldehyde with filtered ultraviolet light gives, respectively, 20% and 80% yields of N,S-diacetylcysteine. In the reaction with 1.0 M acetaldehyde, N-acetylcysteine forms early in the reaction and later decreases with its conversion to N,S-diacetylcysteine. The prebiotic significance of these reactions is discussed.

Clinical and biochemical presentation of sarcoidosis with high and normal serum angiotensin-converting enzyme.

PubMed

Sejdic, A; Graudal, N; Baslund, B

2018-06-22

The presentation of sarcoidosis can involve symptoms from all organs and the diagnosis is therefore often difficult. A raised serum level of serum angiotensin-converting enzyme (sACE) can be detected in 41-58% of patients. However, whether the sACE level per se reflects the severity of the sarcoid inflammation at the onset of the disease is not well described. The purpose of this study was to investigate the clinical and laboratory significance of high versus normal sACE levels in sarcoidosis. Journal data were retrospectively extracted from 101 patients from our clinic. Clinical and biochemical data were compared between patients with high sACE levels (> 115 U/L) on at least one occasion and normal sACE levels (< 115 U/L). In total, 48% (n = 48) of the patients had high ACE and 52% (n = 53) had normal ACE. The most common extrapulmonary manifestation for both groups was arthritis, followed by skin and eye involvement, but none of these differed between the two groups. Serum ionized calcium was significantly higher in the high sACE group, with a correlation coefficient of 0.112 (p = 0.460). Our study demonstrates that serum ionized calcium is significantly higher in the high sACE group but there was no statistical correlation to sACE. No other clinical or biochemical differences were observed.

Selectivity trend of gas separation through nanoporous graphene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Hongjun; Chen, Zhongfang; Dai, Sheng

2015-04-15

By means of molecular dynamics (MD) simulations, we demonstrate that porous graphene can efficiently separate gases according to their molecular sizes. The flux sequence from the classical MD simulation is H{sub 2}>CO{sub 2}≫N{sub 2}>Ar>CH{sub 4}, which generally follows the trend in the kinetic diameters. This trend is also confirmed from the fluxes based on the computed free energy barriers for gas permeation using the umbrella sampling method and kinetic theory of gases. Both brute-force MD simulations and free-energy calcualtions lead to the flux trend consistent with experiments. Case studies of two compositions of CO{sub 2}/N{sub 2} mixtures further demonstrate themore » separation capability of nanoporous graphene. - Graphical abstract: Classical molecular dynamics simulations show the flux trend of H{sub 2}>CO{sub 2}≫N{sub 2}>Ar>CH{sub 4} for their permeation through a porous graphene, in excellent agreement with a recent experiment. - Highlights: • Classical MD simulations show the flux trend of H{sub 2}>CO{sub 2}≫N{sub 2}>Ar>CH{sub 4} for their permeation through a porous graphene. • Free energy calculations yield permeation barriers for those gases. • Selectivities for several gas pairs are estimated from the free-energy barriers and the kinetic theory of gases. • The selectivity trend is in excellent agreement with a recent experiment.« less

Multi-decadal trend and space-time variability of sea level over the Indian Ocean since the 1950s: impact of decadal climate modes

NASA Astrophysics Data System (ADS)

Han, W.; Stammer, D.; Meehl, G. A.; Hu, A.; Sienz, F.

2016-12-01

Sea level varies on decadal and multi-decadal timescales over the Indian Ocean. The variations are not spatially uniform, and can deviate considerably from the global mean sea level rise (SLR) due to various geophysical processes. One of these processes is the change of ocean circulation, which can be partly attributed to natural internal modes of climate variability. Over the Indian Ocean, the most influential climate modes on decadal and multi-decadal timescales are the Interdecadal Pacific Oscillation (IPO) and decadal variability of the Indian Ocean dipole (IOD). Here, we first analyze observational datasets to investigate the impacts of IPO and IOD on spatial patterns of decadal and interdecadal (hereafter decal) sea level variability & multi-decadal trend over the Indian Ocean since the 1950s, using a new statistical approach of Bayesian Dynamical Linear regression Model (DLM). The Bayesian DLM overcomes the limitation of "time-constant (static)" regression coefficients in conventional multiple linear regression model, by allowing the coefficients to vary with time and therefore measuring "time-evolving (dynamical)" relationship between climate modes and sea level. For the multi-decadal sea level trend since the 1950s, our results show that climate modes and non-climate modes (the part that cannot be explained by climate modes) have comparable contributions in magnitudes but with different spatial patterns, with each dominating different regions of the Indian Ocean. For decadal variability, climate modes are the major contributors for sea level variations over most region of the tropical Indian Ocean. The relative importance of IPO and decadal variability of IOD, however, varies spatially. For example, while IOD decadal variability dominates IPO in the eastern equatorial basin (85E-100E, 5S-5N), IPO dominates IOD in causing sea level variations in the tropical southwest Indian Ocean (45E-65E, 12S-2S). To help decipher the possible contribution of external

U.S. conterminous wall-to-wall anthropogenic land use trends (NWALT), 1974–2012

USGS Publications Warehouse

Falcone, James A.

2015-09-14

This dataset provides a U.S. national 60-meter, 19-class mapping of anthropogenic land uses for five time periods: 1974, 1982, 1992, 2002, and 2012. The 2012 dataset is based on a slightly modified version of the National Land Cover Database 2011 (NLCD 2011) that was recoded to a schema of land uses, and mapped back in time to develop datasets for the four earlier eras. The time periods coincide with U.S. Department of Agriculture (USDA) Census of Agriculture data collection years. Changes are derived from (a) known changes in water bodies from reservoir construction or removal; (b) housing unit density changes; (c) regional mining/extraction trends; (d) for 1999–2012, timber and forestry activity based on U.S. Geological Survey (USGS) Landscape Fire and Resource Management Planning Tools (Landfire) data; (e) county-level USDA Census of Agriculture change in cultivated land; and (f) establishment dates of major conservation areas. The data are compared to several other published studies and datasets as validation. Caveats are provided about limitations of the data for some classes. The work was completed as part of the USGS National Water-Quality Assessment (NAWQA) Program and termed the NAWQA Wall-to-Wall Anthropogenic Land Use Trends (NWALT) dataset. The associated datasets include five 60-meter geospatial rasters showing anthropogenic land use for the years 1974, 1982, 1992, 2002, and 2012, and 14 rasters showing the annual extent of timber clearcutting and harvest from 1999 to 2012.

Trends and Divergences in Childhood Income Dynamics, 1970-2010.

PubMed

Hill, Heather D

2018-01-01

Earnings and income variability have increased since the 1970s, particularly at the bottom of the income distribution. Considerable evidence suggests that childhood income levels-captured as average or point-in-time yearly income-are associated with numerous child and adult outcomes. The importance to child development of stable proximal processes during childhood suggests that income variability may also be important, particularly if it is unpredictable, unintentional, or does not reflect an upward trend in family income. Using the Panel Study of Income Dynamics, this study documents trends since the 1970s in three dimensions of childhood income dynamics: level, variability, and growth (n=7991). The analysis reveals that income variability during childhood has grown over time, while income growth rates have not. In addition, the economic context of childhood has diverged substantially by socioeconomic status, race, and family structure, with the most disadvantaged children facing a double-whammy of low income and high variability. © 2018 Elsevier Inc. All rights reserved.

Determining the 13C(α, n)16O absolute cross section through the concurrent application of ANC and THM and astrophysical consequences for the s-process in AGB-LMSs.

NASA Astrophysics Data System (ADS)

Trippella, Oscar; La Cognata, Marco

2018-01-01

The 13C(α, n)16O reaction is considered to be the most important neutron source for the s-process main component in low-mass asymptotic giant branch stars. No direct experimental data exist at very low energies and measurements performed through direct techniques show inconsistent results, mostly in their absolute values. In this context, we reversed the usual normalization procedure combining two indirect approaches, the asymptotic normalization coefficient and the Trojan Horse Method, to unambiguously determine the absolute value of the 13C(α, n)16O astrophysical S(E)-factor in the most relevant energy-region for astrophysics. Adopting the new reaction rate for the n-source in the NEWTON s-process nucleosynthesis code, astrophysical calculations show only limited variations, less than 1%, for those nuclei whose production is considered to be totally due to slow neutron captures.

Trends in surface solar radiation in Spain since the 1980s: the role of the changes in the radiative effects of aerosols and clouds

NASA Astrophysics Data System (ADS)

Sanchez-Lorenzo, Arturo; Mateos, David; Wild, Martin; Calbó, Josep; Antón, Manuel; Enriquez-Alonso, Aaron; Sanchez-Romero, Alex

2014-05-01

There is a growing interest in the study of decadal variations in surface solar radiation, although the analyses of long-term time series in some areas with major gaps in observations, such as in Spain, are still pending. In the first part of this work, a previously published surface solar radiation dataset in Spain is described (for more details, see Sanchez-Lorenzo et al., 2013) based on the longest series with ground-based records of global and diffuse solar radiation, most of them starting in the early 1980s and ending in 2012. Particular emphasis is placed upon the homogenization of this dataset in order to ensure the reliability of the trends. The linear trend in the mean annual series of global solar radiation shows a significant increase since 1981 of 4.0 Wm-2 (or 2.4 %) per decade. These results are in line with the increase of global solar radiation (i.e. brightening period) reported at many worldwide observation sites (Wild, 2009). In addition, the annual mean diffuse solar radiation series shows a significant decrease during the last three decades, but it is disturbed by strong increases in 1983 and 1991-1992, which might reflect the effects of the El Chichón and Pinatubo volcanic eruptions as a result of enhanced scattering of the aerosols emitted during these large volcanic eruptions. As clouds and aerosols are the main sources of uncertainty in the determination of the energy balance of the Earth, there is a growing interest in the evaluation of their radiative effects and their impact on the decadal variability of the surface solar radiation. Hence, in the second part of this work, the changes of the combined radiative effects of clouds and aerosols in Spain since the 1980s are investigated (for more details, see Mateos et al., 2013). In particular, the global solar radiation data above mentioned and radiative transfer simulations fed with reanalysis data of ozone, water vapour and surface albedo, are used to evaluate the cloud and aerosol

Astrophysical S factor for the radiative capture {sup 12}N(p,{gamma}){sup 13}O determined from the {sup 14}N({sup 12}N,{sup 13}O){sup 13}C proton transfer reaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Banu, A.; Al-Abdullah, T.; Fu, C.

2009-02-15

The cross section of the radiative proton capture reaction on the drip line nucleus {sup 12}N was investigated using the asymptotic normalization coefficient (ANC) method. We have used the {sup 14}N({sup 12}N,{sup 13}O){sup 13}C proton transfer reaction at 12 MeV/nucleon to extract the ANC for {sup 13}O{yields}{sup 12}N+p and calculate from it the direct component of the astrophysical S factor of the {sup 12}N(p,{gamma}){sup 13}O reaction. The optical potentials used and the distorted-wave Born approximation analysis of the proton transfer reaction are discussed. For the entrance channel, the optical potential was inferred from an elastic scattering measurement carried out atmore » the same time as the transfer measurement. From the transfer, we determined the square of the ANC, C{sub p{sub 1/2}}{sup 2}({sup 13}O{sub g.s.})=2.53{+-}0.30 fm{sup -1}, and hence a value of 0.33(4) keV b was obtained for the direct astrophysical S factor at zero energy. Constructive interference at low energies between the direct and resonant captures leads to an enhancement of S{sub total}(0)=0.42(6) keV b. The {sup 12}N(p,{gamma}){sup 13}O reaction was investigated in relation to the evolution of hydrogen-rich massive Population III stars, for the role that it may play in the hot pp-chain nuclear burning processes, possibly occurring in such objects.« less

Sub-cellular force microscopy in single normal and cancer cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Babahosseini, H.; Carmichael, B.; Strobl, J.S.

2015-08-07

This work investigates the biomechanical properties of sub-cellular structures of breast cells using atomic force microscopy (AFM). The cells are modeled as a triple-layered structure where the Generalized Maxwell model is applied to experimental data from AFM stress-relaxation tests to extract the elastic modulus, the apparent viscosity, and the relaxation time of sub-cellular structures. The triple-layered modeling results allow for determination and comparison of the biomechanical properties of the three major sub-cellular structures between normal and cancerous cells: the up plasma membrane/actin cortex, the mid cytoplasm/nucleus, and the low nuclear/integrin sub-domains. The results reveal that the sub-domains become stiffer andmore » significantly more viscous with depth, regardless of cell type. In addition, there is a decreasing trend in the average elastic modulus and apparent viscosity of the all corresponding sub-cellular structures from normal to cancerous cells, which becomes most remarkable in the deeper sub-domain. The presented modeling in this work constitutes a unique AFM-based experimental framework to study the biomechanics of sub-cellular structures. - Highlights: • The cells are modeled as a triple-layered structure using Generalized Maxwell model. • The sub-domains include membrane/cortex, cytoplasm/nucleus, and nuclear/integrin. • Biomechanics of corresponding sub-domains are compared among normal and cancer cells. • Viscoelasticity of sub-domains show a decreasing trend from normal to cancer cells. • The decreasing trend becomes most significant in the deeper sub-domain.« less

Missile Misdistance Reduction: An Instructive Methodology for Developing Terminal Guidance Control Systems to Minimize Missile Misdistance.

DTIC Science & Technology

1982-10-01

ZHTAM NORMAS IZED MISSILE*S DISPLACEMENT OFF-L.O.S * NCAACC NORMALIZED MISSILE’S ACCELERATION &YAN TAM "(I/(I-N(K) ))*(I-TIMEI*flL-TIMEJ**(N(KI-)--I...Interceptor Missiles, April 1976. 8. George, L. C., "Missile Guidance and Control System De- sign Trends," SAE paper, National Aerospace Engineering and

Foundation on Economic Trends v. Bowen.

PubMed

1989-10-04

The National Enviromental Policy Act requires that government agencies make a detailed enviromental impact statement (EIS) for all research significantly affecting the environment. These statements must be supplemented if the project substantially changes or if new information is obtained. The Foundation on Economic Trends argued that three developments in recombinant DNA research will significantly alter the enviromental impact, thereby mandating a new EIS by the National Institutes of Health (NIH). These developments are cloning oncogenic viruses, engineering the human immunodeficiency virus into cells not normally susceptible to it, and introducing AIDS genetic codes into mice. The U.S. District Court, District of Columbia, held that the first two projects do not pose a greater risk and that the enviromental assessment being prepared by NIH on the third satisfies the requirements of the National Enviromental Policy Act.

Tumor Response and Apoptosis of N1-S1 Rodent Hepatomas in Response to Intra-arterial and Intravenous Benzamide Riboside

DOE Office of Scientific and Technical Information (OSTI.GOV)

McLennan, Gordon, E-mail: gmclenna@me.com; Bennett, Stacy L.; Ju, Shenghong

2012-06-15

Purpose: Benzamide riboside (BR) induces tumor apoptosis in multiple cell lines and animals. This pilot study compares apoptosis and tumor response in rat hepatomas treated with hepatic arterial BR (IA) or intravenous (IV) BR. Methods: A total of 10{sup 6} N1-S1 cells were placed in the left hepatic lobes of 15 Sprague-Dawley rats. After 2 weeks, BR (20 mg/kg) was infused IA (n = 5) or IV (n = 5). One animal in each group was excluded for technical factors, which prevented a full dose administration (1 IA and 1 IV). Five rats received saline (3 IA and 2 IV).more » Animals were killed after 3 weeks. Tumor volumes after IA and IV treatments were analyzed by Wilcoxon rank sum test. The percentage of tumor and normal liver apoptosis was counted by using 10 fields of TUNEL (terminal deoxynucleotidyl transferase dUTP nick-end labeling)-stained slides at 40 Multiplication-Sign magnification. The percentage of apoptosis was compared between IV and IA administrations and with saline sham-treated rats by the Wilcoxon rank sum test. Results: Tumors were smaller after IA treatment, but this did not reach statistical significance (0.14 IA vs. 0.57 IV; P = 0.138). There was much variability in percentage of apoptosis and no significant difference between IA and IV BR (44.49 vs. 1.52%; P = 0.18); IA BR and saline (44.49 vs. 33.83%; P = 0.66); or IV BR and saline (1.52 vs. 193%; P = 0.18). Conclusions: Although differences in tumor volumes did not reach statistical significance, there was a trend toward smaller tumors after IA BR than IV BR in this small pilot study. Comparisons of these treatment methods will require a larger sample size and repeat experimentation.« less

External quality assurance project report for the National Atmospheric Deposition Program’s National Trends Network and Mercury Deposition Network, 2015–16

USGS Publications Warehouse

Wetherbee, Gregory A.; Martin, RoseAnn

2018-06-29

The U.S. Geological Survey Precipitation Chemistry Quality Assurance project operated five distinct programs to provide external quality assurance monitoring for the National Atmospheric Deposition Program’s (NADP) National Trends Network and Mercury Deposition Network during 2015–16. The National Trends Network programs include (1) a field audit program to evaluate sample contamination and stability, (2) an interlaboratory comparison program to evaluate analytical laboratory performance, and (3) a colocated sampler program to evaluate bias and variability attributed to automated precipitation samplers. The Mercury Deposition Network programs include the (4) system blank program and (5) an interlaboratory comparison program. The results indicate that NADP data continue to be of sufficient quality for the analysis of spatial distributions and time trends for chemical constituents in wet deposition.The field audit program results indicate increased sample contamination for calcium, magnesium, and potassium relative to 2010 levels, and slight fluctuation in sodium contamination. Nitrate contamination levels dropped slightly during 2014–16, and chloride contamination leveled off between 2007 and 2016. Sulfate contamination is similar to the 2000 level. Hydrogen ion contamination has steadily decreased since 2012. Losses of ammonium and nitrate resulting from potential sample instability were negligible.The NADP Central Analytical Laboratory produced interlaboratory comparison results with low bias and variability compared to other domestic and international laboratories that support atmospheric deposition monitoring. Significant absolute bias above the magnitudes of the detection limits was observed for nitrate and sulfate concentrations, but no analyte determinations exceeded the detection limits for blanks.Colocated sampler program results from dissimilar colocated collectors indicate that the retrofit of the National Trends Network with N-CON Systems Company

Secondhand smoke exposure in cars and rooms: trend comparisons among subpopulations of nonsmoking U.S. middle and high school students.

PubMed

McIntire, Russell K; Macy, Jonathan T; Seo, Dong-Chul; Nelson, Ashlyn A; Kolbe, Lloyd J

2014-06-01

Young people in the United States are exposed to secondhand smoke (SHS) primarily in 2 settings: homes and cars. Recently, researchers reported that the prevalence of U.S students exposed to SHS in cars decreased from 2000 to 2009; however, comparisons of trends across school levels, gender, and racial/ethnic groups were not assessed. Moreover, no studies have examined trends of exposure to SHS in rooms. We used data from the 2000, 2002, 2004, 2006, and 2009 waves of the National Youth Tobacco Survey, a nationally representative cross-sectional survey of U.S. middle and high school students. For SHS in cars and rooms, we identified exposure trends among nonsmokers from 2000 to 2009 and compared trends across subpopulations with binary logistic regression. We identified significant downward linear trends in SHS in cars and rooms for nearly all measured subpopulations of nonsmoking students from 2000 to 2009. SHS exposure in cars and rooms declined at a significantly greater rate for males than for females. SHS exposure in cars declined at a significantly greater rate for non-Hispanic (NH) Blacks than for NH Whites. SHS exposure in rooms declined at a significantly greater rate for NH Whites than for Hispanics and Native Hawaiians/Pacific Islanders. Although prevalence of exposure to SHS in cars and rooms among nonsmoking U.S. middle and high school students has declined from 2000 to 2009, the rates of decline were not equal across genders and racial/ethnic groups. Identification of these differing rates of exposure can help the public health community advocate for interventions focused on reducing adolescent SHS exposure.

Dissociating Normal Aging from Alzheimer’s Disease: A View from Cognitive Neuroscience

PubMed Central

Toepper, Max

2017-01-01

Both normal aging and Alzheimer’s disease (AD) are associated with changes in cognition, grey and white matter volume, white matter integrity, neural activation, functional connectivity, and neurotransmission. Obviously, all of these changes are more pronounced in AD and proceed faster providing the basis for an AD diagnosis. Since these differences are quantitative, however, it was hypothesized that AD might simply reflect an accelerated aging process. The present article highlights the different neurocognitive changes associated with normal aging and AD and shows that, next to quantitative differences, there are multiple qualitative differences as well. These differences comprise different neurocognitive dissociations as different cognitive deficit profiles, different weights of grey and white matter atrophy, and different gradients of structural decline. These qualitative differences clearly indicate that AD cannot be simply described as accelerated aging process but on the contrary represents a solid entity. PMID:28269778

Years of Challenge: The Impact of Demographic and Work Force Trends on Higher Education in the 1990s. A NACUBO Monograph.

ERIC Educational Resources Information Center

Hughes, K. Scott; And Others

This report describes national demographic and work force trends that have important implications for institutions and presents recommended management strategies for the 1990s. Among the trends predicted for the next 10 years are the following: (1) a continuing reduction in the traditional 18-24 year-old college-going population; (2) the…

S&T converging trends in dealing with disaster: A review on AI tools

NASA Astrophysics Data System (ADS)

Hasan, Abu Bakar; Isa, Mohd. Hafez Mohd.

2016-01-01

Science and Technology (S&T) has been able to help mankind to solve or minimize problems when arise. Different methodologies, techniques and tools were developed or used for specific cases by researchers, engineers, scientists throughout the world, and numerous papers and articles have been written by them. Nine selected cases such as flash flood, earthquakes, workplace accident, fault in aircraft industry, seismic vulnerability, disaster mitigation and management, and early fault detection in nuclear industry have been studied. This paper looked at those cases, and their results showed nearly 60% uses artificial intelligence (AI) as a tool. This paper also did some review that will help young researchers in deciding the types of AI tools to be selected; thus proving the future trends in S&T.

Urinary mRNA for the Diagnosis of Renal Allograft Rejection: The Issue of Normalization.

PubMed

Galichon, P; Amrouche, L; Hertig, A; Brocheriou, I; Rabant, M; Xu-Dubois, Y-C; Ouali, N; Dahan, K; Morin, L; Terzi, F; Rondeau, E; Anglicheau, D

2016-10-01

Urinary messenger RNA (mRNA) quantification is a promising method for noninvasive diagnosis of renal allograft rejection (AR), but the quantification of mRNAs in urine remains challenging due to degradation. RNA normalization may be warranted to overcome these issues, but the strategies of gene normalization have been poorly evaluated. Herein, we address this issue in a case-control study of 108 urine samples collected at time of allograft biopsy in kidney recipients with (n = 52) or without (n = 56) AR by comparing the diagnostic value of IP-10 and CD3ε mRNAs-two biomarkers of AR-after normalization by the total amount of RNA, normalization by one of the three widely used reference RNAs-18S, glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Hypoxanthine-guanine phosphoribosyltransferase (HPRT)-or normalization using uroplakin 1A (UPK) mRNA as a possible urine-specific reference mRNA. Our results show that normalization based on the total quantity of RNA is not substantially improved by additional normalization and may even be worsened with some classical reference genes that are overexpressed during rejection. However, considering that normalization by a reference gene is necessary to ensure polymerase chain reaction (PCR) quality and reproducibility and to suppress the effect of RNA degradation, we suggest that GAPDH and UPK1A are preferable to 18S or HPRT RNA. © Copyright 2016 The American Society of Transplantation and the American Society of Transplant Surgeons.

Total ozone trends over the USA during 1979-1991 from Dobson spectrophotometer observations

NASA Technical Reports Server (NTRS)

Komhyr, Walter D.; Grass, Robert D.; Koenig, Gloria L.; Quincy, Dorothy M.; Evans, Robert D.; Leonard, R. Kent

1994-01-01

Ozone trends for 1979-1991, determined from Dobson spectrophotometer observations made at eight stations in the United States, are augmented with trend data from four foreign cooperative stations operated by NOAA/CMDL. Results are based on provisional data archived routinely throughout the years at the World Ozone Data Center in Toronto, Canada, with calibration corrections applied to some of the data. Trends through 1990 exhibit values of minus 0.3 percent to minus 0.5 percent yr(exp -1) at mid-to-high latitudes in the northern hemisphere. With the addition of 1991 data, however, the trends become less negative, indicating that ozone increased in many parts of the world during 1991. Stations located within the plus or minus 20 deg N-S latitude band exhibit no ozone trends. Early 1992 data show decreased ozone values at some of the stations. At South Pole, Antarctica, October ozone values have remained low during the past 3 years.

Causes of spring vegetation greenness trends in the northern mid-high latitudes from 1982 to 2004

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mao, Jiafu; Shi, Xiaoying; Thornton, Peter E

2012-01-01

The Community Land Model version 4 (CLM4) is applied to explore the spatial temporal patterns of spring (April May) vegetation growth trends over the northern mid high latitudes (NMH) (>25 N) between 1982 and 2004. During the spring season through the 23 yr period, both the satellite-derived and simulated normalized difference vegetation index (NDVI) anomalies show a statistically significant correlation and an overall greening trend within the study area. Consistently with the observed NDVI temperature relation, the CLM4 NDVI shows a significant positive association with the spring temperature anomaly for the NMH, North America and Eurasia. Large study areas experiencemore » temperature discontinuity associated with contrasting NDVI trends. Before and after the turning point (TP) of the temperature trends, climatic variability plays a dominant role, while the other environmental factors exert minor effects on the NDVI tendencies. Simulated vegetation growth is broadly stimulated by the increasing atmospheric CO2. Trends show that nitrogen deposition increases NDVI mostly in southeastern China, and decreases NDVI mainly in western Russia after the temperature TP. Furthermore, land use-induced NDVI trends vary roughly with the respective changes in land management practices (crop areas and forest coverage). Our results highlight how non-climatic factors mitigate or exacerbate the impact of temperature on spring vegetation growth, particularly across regions with intensive human activity.« less

Trends in New U.S. Marine Corps Accessions During the Recent Conflicts in Iraq and Afghanistan

DTIC Science & Technology

2014-01-01

modest changes over the study period. Favorable trends included recent (2009-2010) improvernents in body mass index and physical activity levels...height, body mass index (BMI) in kg/m^ was calculated. Frequency of physical activity before service entry was assessed from self-report. Initial run...Test; BMI, body mass index; mph, miles per hour; SD, standard deviation. "Numbers (n) may not add up to 131,961 because of missing self-reported data for

The GlcN6P cofactor serves multiple catalytic roles in the glmS ribozyme

PubMed Central

Bingaman, Jamie L.; Zhang, Sixue; Stevens, David R.; Yennawar, Neela H.; Hammes-Schiffer, Sharon; Bevilacqua, Philip C.

2017-01-01

RNA enzymes have remarkably diverse biological roles despite having limited chemical diversity. Protein enzymes enhance their reactivity through recruitment of cofactors. The naturally occurring glmS ribozyme uses the glucosamine-6-phosphate (GlcN6P) organic cofactor for phosphodiester bond cleavage. Prior structural and biochemical studies implicated GlcN6P as the general acid. Here we describe new catalytic roles for GlcN6P through experiments and calculations. Large stereospecific normal thio effects and lack of metal ion rescue in the holoribozyme show that nucleobases and the cofactor play direct chemical roles and align the active site for self-cleavage. Large stereospecific inverse thio effects in the aporibozyme suggest that the GlcN6P cofactor disrupts an inhibitory interaction of the nucleophile. Strong metal ion rescue in the aporibozyme reveals this cofactor also provides electrostatic stabilization. Ribozyme organic cofactors thus perform myriad catalytic roles, allowing RNA to compensate for its limited functional diversity. PMID:28192411

A feasibility study in adapting Shamos Bickel and Hodges Lehman estimator into T-Method for normalization

NASA Astrophysics Data System (ADS)

Harudin, N.; Jamaludin, K. R.; Muhtazaruddin, M. Nabil; Ramlie, F.; Muhamad, Wan Zuki Azman Wan

2018-03-01

T-Method is one of the techniques governed under Mahalanobis Taguchi System that developed specifically for multivariate data predictions. Prediction using T-Method is always possible even with very limited sample size. The user of T-Method required to clearly understanding the population data trend since this method is not considering the effect of outliers within it. Outliers may cause apparent non-normality and the entire classical methods breakdown. There exist robust parameter estimate that provide satisfactory results when the data contain outliers, as well as when the data are free of them. The robust parameter estimates of location and scale measure called Shamos Bickel (SB) and Hodges Lehman (HL) which are used as a comparable method to calculate the mean and standard deviation of classical statistic is part of it. Embedding these into T-Method normalize stage feasibly help in enhancing the accuracy of the T-Method as well as analysing the robustness of T-method itself. However, the result of higher sample size case study shows that T-method is having lowest average error percentages (3.09%) on data with extreme outliers. HL and SB is having lowest error percentages (4.67%) for data without extreme outliers with minimum error differences compared to T-Method. The error percentages prediction trend is vice versa for lower sample size case study. The result shows that with minimum sample size, which outliers always be at low risk, T-Method is much better on that, while higher sample size with extreme outliers, T-Method as well show better prediction compared to others. For the case studies conducted in this research, it shows that normalization of T-Method is showing satisfactory results and it is not feasible to adapt HL and SB or normal mean and standard deviation into it since it’s only provide minimum effect of percentages errors. Normalization using T-method is still considered having lower risk towards outlier’s effect.

Scoliosis in Duchenne’s muscular dystrophy: a changing trend in surgical management

PubMed Central

Srinivas, S.; Mehdian, S. M. H.

2009-01-01

A non-randomised retrospective study to compare the results of surgical correction of scoliosis in Duchenne’s muscular dystrophy (DMD) patients using three different instrumentation systems—Sublaminar instrumentation system (Group A), a hybrid of sublaminar and pedicle screw systems (Group B) and pedicle screw system alone (Group C). Between 1993 and 2003, 43 patients with DMD underwent posterior spinal fusion and instrumentation. Group A (n = 19) had sublaminar instrumentation system, Group B (n = 13) had a hybrid construct and Group C (n = 11) was treated with pedicle system. The mean blood loss in Group A was 4.1 l, 3.2 l in Group B and 2.5 l in Group C. Average operating times in Group A, B and C were 300, 274 and 234 min, respectively. Mean pre-operative, post-operative and final Cobb angle in Group A was 50.05 ± 15.46°, 15.68 ± 11.23° and 21.57 ± 11.63°, Group B was 17.76 ± 8.50°, 3.61 ± 2.53° and 6.69 ± 4.19° and Group C was 25.81 ± 9.94°, 5.45 ± 3.88°, 8.90 ± 5.82°, respectively. Flexibility index or the potential correction calculated from bending radiographs were 60 ± 6.33, 70 ± 4.65 and 67 ± 6.79% for Group A, Group B and Group C respectively. The percentage correction achieved was 72.5 ± 14.5% in Group A, 82 ± 6% in Group B and 82 ± 8% in Group C. The difference between percentage correction achieved and the flexibility index was 12.45 ± 8.22, 12.05 ± 1.3 and 15.00 ± 1.21% in Group A, B and C, respectively The percentage loss of correction in Cobb angles at final follow-up in Group A, B and C was 12.5 ± 3.5, 16.5 ± 1. and 12.5 ± 2.5%, respectively. Complications seen in Group A were three cases of wound infection and two cases of implant failure; Group B had a single case of implant failure and Group C had one patient with wound infection and one case with a partial screw pull out. Early surgery and smaller curve corrections appears to be the current trend in the

Trends in E-Cigarette Awareness and Perceived Harmfulness in the U.S.

PubMed

Huerta, Timothy R; Walker, Daniel M; Mullen, Deborah; Johnson, Tyler J; Ford, Eric W

2017-03-01

Electronic cigarettes (e-cigarettes) are gaining in popularity as an alternative to regular cigarettes, as they are viewed as potentially less harmful. However, it remains unclear how awareness about e-cigarettes is permeating through the general U.S. This study seeks to extend previous research and examine trends in e-cigarette awareness and perceived harmfulness, and their association with smoking-cessation efforts. Data from three cycles (2012, 2013, and 2014) of the Health Information National Trends Survey were combined into a single data set. Controlling for survey year, multivariate logit models were used to determine the association between demographic characteristics and e-cigarette awareness, perceived harmfulness, quit attempts, and quit intentions. Data were analyzed in 2015. Awareness of e-cigarettes increased from 77.1% in 2012 to 94.3% in 2014. Controlling for demographic characteristics, e-cigarette awareness significantly increased in both 2013 and 2014, relative to 2012. Perception that e-cigarettes were less harmful than regular cigarettes declined from 50.7% in 2012 to 43.1% in 2014. Among smokers, no relationship was observed between e-cigarette awareness and past-year quit attempts or quit intentions, but those that viewed e-cigarettes as less harmful were less likely to have a past-year quit attempt. These analyses reveal a continued increase in overall public awareness of e-cigarettes and shifting harm perceptions relative to regular cigarettes. New regulatory oversight by the U.S. Food and Drug Administration may have major effects on both dimensions, which are worth continued monitoring. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Excitations Élémentaires au Voisinage de la Surface de Séparation d'un Métal Normal et d'un Métal Supraconducteur

NASA Astrophysics Data System (ADS)

Saint-James, Par D.

On étudie le spectre d'excitation pour une couche de métal normal déposée sur un supraconducteur. On montre que si l'interaction attractive électron-électron est négligeable dans le métal normal, il n'y a pas de gap d'énergie dans le spectre d'excitation, même si l'épaisseur de la couche normale est petite. Une étude analogue, conduisant à une conclusion similaire, est menée pour deux supraconducteurs accolés et pour des sphères de métal normal baignant dans un supraconducteur. L'effet prévu pourrait expliquer quelques résultats particuliers observés dans des mesures d'effet tunnel dans des supraconducteurs durs. The excitation spectrum of a layer of normal metal (N) deposited on a superconducting substrate (S) is discussed. It is shown that if the electron-electron attractive interaction is negligibly small in (N) there is no energy gap in the excitation spectrum even if the thickness of the layer (N) is small. A similar study, with equivalent conclusions, has been carried out for two superconductors and for normal metal spheres embedded in a superconductor. The effect may possibly explain some peculiar results of tunnelling experiments on hard superconductors.

Trends in disability of instrumental activities of daily living among older Chinese adults, 1997-2006: population based study.

PubMed

Liang, Yajun; Welmer, Anna-Karin; Möller, Jette; Qiu, Chengxuan

2017-08-28

Data on trends for disability in instrumental activity of daily living (IADL) are sparse in older Chinese adults. To assess trends in prevalence and incidence of IADL disability among older Chinese adults and to explore contributing factors. Population based study. 15 provinces and municipalities in China. Participants (age ≥60) were from four waves of the China Health and Nutrition Survey, conducted in 1997 (n=1533), 2000 (n=1581), 2004 (n=2028) and 2006 (n=2256), and from two cohorts constructed within the national survey: cohort 1997-2004 (n=712) and cohort 2000-2006 (n=823). IADL disability was defined as inability to perform one or more of the following: shopping, cooking, using transportation, financing and telephoning. Data were analysed with logistic regression and generalised estimating equation models. The prevalence of IADL disability significantly decreased from 1997 to 2006 in the total sample and in all of the subgroups by age, sex, living region and IADL items (all p trend <0.05). The incidence of IADL disability remained stable from cohort 1997-2004 to cohort 2000-2006 in the total sample and in all of the subgroups (all p>0.10). The recovery rate from IADL disability significantly increased over time in those aged 60-69 years (p=0.03). Living in a rural area or access to local clinics for healthcare was less disabling over time (p trend <0.02). The prevalence of IADL disability decreased among older Chinese adults during 1997-2006, whereas the incidence remained stable. The declining prevalence of IADL disability might be partly due to the decreased duration of IADL disability, and to improvements in living conditions and healthcare facilities over time. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

AFM stiffness nanotomography of normal, metaplastic and dysplastic human esophageal cells

NASA Astrophysics Data System (ADS)

Fuhrmann, A.; Staunton, J. R.; Nandakumar, V.; Banyai, N.; Davies, P. C. W.; Ros, R.

2011-02-01

The mechanical stiffness of individual cells is important in tissue homeostasis, cell growth, division and motility, and the epithelial-mesenchymal transition in the initiation of cancer. In this work, a normal squamous cell line (EPC2) and metaplastic (CP-A) as well as dysplastic (CP-D) Barrett's Esophagus columnar cell lines are studied as a model of pre-neoplastic progression in the human esophagus. We used the combination of an atomic force microscope (AFM) with a scanning confocal fluorescence lifetime imaging microscope to study the mechanical properties of single adherent cells. Sixty four force indentation curves were taken over the nucleus of each cell in an 8 × 8 grid pattern. Analyzing the force indentation curves, indentation depth-dependent Young's moduli were found for all cell lines. Stiffness tomograms demonstrate distinct differences between the mechanical properties of the studied cell lines. Comparing the stiffness for indentation forces of 1 nN, most probable Young's moduli were calculated to 4.7 kPa for EPC2 (n = 18 cells), 3.1 kPa for CP-A (n = 10) and 2.6 kPa for CP-D (n = 19). We also tested the influence of nuclei and nucleoli staining organic dyes on the mechanical properties of the cells. For stained EPC2 cells (n = 5), significant stiffening was found (9.9 kPa), while CP-A cells (n = 5) showed no clear trend (2.9 kPa) and a slight softening was observed (2.1 kPa) in the case of CP-D cells (n = 16). Some force-indentation curves show non-monotonic discontinuities with segments of negative slope, resembling a sawtooth pattern. We found the incidence of these 'breakthrough events' to be highest in the dysplastic CP-D cells, intermediate in the metaplastic CP-A cells and lowest in the normal EPC2 cells. This observation suggests that the microscopic explanation for the increased compliance of cancerous and pre-cancerous cells may lie in their susceptibility to 'crumble and yield' rather than their ability to 'bend and flex'.

The large-N Yang-Mills S matrix is ultraviolet finite, but the large-N QCD S matrix is only renormalizable

NASA Astrophysics Data System (ADS)

Bochicchio, Marco

2017-03-01

Yang-Mills (YM) theory and QCD are known to be renormalizable, but not ultraviolet (UV) finite, order by order, in perturbation theory. It is a fundamental question whether YM theory or QCD is UV finite, or only renormalizable, order by order, in the large-N 't Hooft or Veneziano expansions. We demonstrate that the renormalization group (RG) and asymptotic freedom imply that in 't Hooft large-N expansion the S matrix in YM theory is UV finite, while in both 't Hooft and Veneziano large-N expansions, the S matrix in confining massless QCD is renormalizable but not UV finite. By the same argument, the large-N N =1 supersymmetry (SUSY) YM S matrix is UV finite as well. Besides, we demonstrate that, in both 't Hooft and Veneziano large-N expansions, the correlators of local gauge-invariant operators, as opposed to the S matrix, are renormalizable but, in general, not UV finite, either in YM theory and N =1 SUSY YM theory or a fortiori in massless QCD. Moreover, we compute explicitly the counterterms that arise from renormalizing the 't Hooft and Veneziano expansions by deriving in confining massless QCD-like theories a low-energy theorem of the Novikov-Shifman-Vainshtein-Zakharov type that relates the log derivative with respect to the gauge coupling of a k -point correlator, or the log derivative with respect to the RG-invariant scale, to a (k +1 )-point correlator with the insertion of Tr F2 at zero momentum. Finally, we argue that similar results hold in the large-N limit of a vast class of confining massive QCD-like theories, provided a renormalization scheme exists—as, for example, MS ¯ —in which the beta function is not dependent on the masses. Specifically, in both 't Hooft and Veneziano large-N expansions, the S matrix in confining massive QCD and massive N =1 SUSY QCD is renormalizable but not UV finite.

A decade of monitoring at Swiss Long-Term Forest Ecosystem Research (LWF) sites: can we observe trends in atmospheric acid deposition and in soil solution acidity?

PubMed

Pannatier, Elisabeth Graf; Thimonier, Anne; Schmitt, Maria; Walthert, Lorenz; Waldner, Peter

2011-03-01

Trends in atmospheric acid deposition and in soil solution acidity from 1995 or later until 2007 were investigated at several forest sites throughout Switzerland to assess the effects of air pollution abatements on deposition and the response of the soil solution chemistry. Deposition of the major elements was estimated from throughfall and bulk deposition measurements at nine sites of the Swiss Long-Term Forest Ecosystem Research network (LWF) since 1995 or later. Soil solution was measured at seven plots at four soil depths since 1998 or later. Trends in the molar ratio of base cations to aluminum (BC/Al) in soil solutions and in concentrations and fluxes of inorganic N (NO(3)-N + NH(4)-N), sulfate (SO(4)-S), and base cations (BC) were used to detect changes in soil solution chemistry. Acid deposition significantly decreased at three out of the nine study sites due to a decrease in total N deposition. Total SO(4)-S deposition decreased at the nine sites, but due to the relatively low amount of SO(4)-S load compared to N deposition, it did not contribute to decrease acid deposition significantly. No trend in total BC deposition was detected. In the soil solution, no trend in concentrations and fluxes of BC, SO(4)-S, and inorganic N were found at most soil depths at five out of the seven sites. This suggests that the soil solution reacted very little to the changes in atmospheric deposition. A stronger reduction in base cations compared to aluminum was detected at two sites, which might indicate that acidification of the soil solution was proceeding faster at these sites.

Foreign medical graduates in the 1980s: trends in specialization.

PubMed Central

Mick, S S; Worobey, J L

1984-01-01

Secondary analysis of data collected by the American Medical Association and the Graduate Medical Education National Advisory Committee (GMENAC) suggests that measures to diminish the flow of alien Foreign Medical Graduates (FMGs) into the United States have been less effective than planned. Declining trends in the proportion of FMG house officers in the mid- to late-1970s have recently stabilized around 19 per cent. There has also been a dramatic increase in the number of US citizen Foreign Medical Graduates ( USFMGs ) in house officer positions. A pattern of alien FMG and USFMG house officer specialization correlates with specialties designated by the GMENAC as shortage areas by 1990 (r = -.49, p less than .05). Despite the GMENAC prediction of a surplus of physicians by 1990, differential selection of alien FMGs and USFMGs into shortage specialties may assure their substantial future presence in the US health care system. PMID:6742255

U.S. motor vehicle fatality trends in young Latino males.

PubMed

Vaca, Federico; Anderson, Craig L

2009-10-01

The Latino Epidemiologic Paradox describes favorable health profiles for Latinos compared to non-Latino Whites (NLW) despite poverty, low education, and low access to health care. An anomaly to this paradox is increased mortality of Latino adolescent and emerging adult males. Previous research shows motor vehicle crash fatalities bear a considerable proportion of the mortality burden attributed to this anomaly. Utilizing two U.S. data sources (CDC-WISQARS and NHTSA-FARS), graphical and linear regression methods were used to analyze crash fatality trends and changes in factors that influence crash injury fatality among young Latino males age 15-24. During 1999-2006, 59,719 motor vehicle fatalities occurred among Latino, NLW and Non-Latino Black (NLB) young males. Fatality rates were 37.7, 39.6, and 29.8 per 100,000 population/year for Latinos, NLW and NLB respectively. Over the study period, young Latino male mortality rates increased 27%. By 2006, fatality rates were 41.9, 38.3 and 27.8 per 100,000 population/year for Latinos, NLW and NLB respectively. Among driver fatalities, 43% Latino, 33% NLW and 27% NLB were restrained. Fifty-seven percent of Latino drivers had blood alcohol >or=0.01 g/dl (BAC+), as did 47% of NLW drivers and 42% of NLB drivers. Over the study period, BAC+ changed little among Latinos and NLW drivers but decreased among NLB drivers. Motor vehicle fatality rates for young Latino males are rising despite increasing restraint use and leveling driver BAC+. Without racial/ethnic specific exposure data, limitations exist in discerning the cause of diverging fatality trends and further understanding specific racial/ethnic group crash fatality disparities.

Status and trends in atmospheric deposition and emissions near Atlanta, Georgia, 1986-99

USGS Publications Warehouse

Peters, N.E.; Meyers, T.P.; Aulenbach, Brent T.

2002-01-01

Wet and dry atmospheric deposition were investigated from weekly data, 1986-99 (1986-97 for dry deposition) at the Panola Mountain Research Watershed (PMRW), a forested research site 25 km, southeast of Atlanta, Georgia. Furthermore, the wet deposition was compared to that at three adjacent National Atmospheric Deposition Program's National Trends Network (NTN) sites (GA41, 50 km south of PMRW; AL99, 175 km northwest; NC25, 175 km north-northeast) and dry deposition was compared to that at adjacent Clean Air Status and Trends Network (CASTNET) sites, co-located at the NTN sites. The pH of precipitation is acidic and the dominant acid anion is SO4; the pH (derived from the volume-weighted mean H concentration) averages 4.44 for 1986-99, and varies seasonally with average lowest values in summer (4.19) and highest in winter (4.63). From 1986-99, the annual wet deposition of sulfur (S) and nitrogen (N) averaged 400 and 300 eq ha-1 (6.4 and 4.2 kg ha-1), respectively. Inferential model estimates of annual dry S and N deposition from 1986-97 averaged 130 and 150 eq ha-1 (2.1 and 2.1 kg ha-1), respectively. From 1993-99, net S deposition (dry deposition plus canopy interactions) for coniferous and deciduous throughfall (throughfall minus wet-only deposition) averaged 400 and 150 eq ha-1 (6.4 and 2.1 kg ha-1), respectively. The annual wet deposition of S and N species at PMRW was comparable to that at NTN sites, with the exception of higher N species deposition at AL99 and relatively lower H, SO4 and NO3 deposition at GA41. Dry S deposition at PMRW differed markedly from the CASTNET sites despite similarity in S concentrations for all but NC25; the differences are attributed to differences in model parameters associated with the landscape and vegetation characteristics at the sites. At PMRW, atmospheric deposition trends were not detected for the entire sampling period, but were detected for shorter periods (4-5yr). Annual S and N deposition increased from 1986 to 1991

Identity Formation, Marijuana and “The Self”: A Study of Cannabis Normalization among University Students

PubMed Central

Mostaghim, Amir; Hathaway, Andrew D.

2013-01-01

Over the past half-century, as use of marijuana has become more widespread in Canadian society, there are indications of a normalizing process in societal reactions and experiences of use. Among other research avenues, these trends suggest a need for further exploration of young people’s understandings of how they make the choice to use or not and how decisions relate to presentation of the self. This study draws on interviews with 30 undergraduates recruited from a larger online survey of respondents at the University of Guelph, ON, Canada. In probing their perceptions of the use of marijuana, we often found that trying/using “pot” was the default option, whereas choosing not to use required more conscious effort. With specific reference to Goffman’s contribution to a situated understanding of the self, our findings are interpreted with emphasis on further theoretical development of the normalization thesis and on the role of marijuana in identity formation among persons in the process of transition to adulthood. PMID:24348431

Multiple long-term trends and trend reversals dominate environmental conditions in a man-made freshwater reservoir.

PubMed

Znachor, Petr; Nedoma, Jiří; Hejzlar, Josef; Seďa, Jaromír; Kopáček, Jiří; Boukal, David; Mrkvička, Tomáš

2018-05-15

Man-made reservoirs are common across the world and provide a wide range of ecological services. Environmental conditions in riverine reservoirs are affected by the changing climate, catchment-wide processes and manipulations with the water level, and water abstraction from the reservoir. Long-term trends of environmental conditions in reservoirs thus reflect a wider range of drivers in comparison to lakes, which makes the understanding of reservoir dynamics more challenging. We analysed a 32-year time series of 36 environmental variables characterising weather, land use in the catchment, reservoir hydrochemistry, hydrology and light availability in the small, canyon-shaped Římov Reservoir in the Czech Republic to detect underlying trends, trend reversals and regime shifts. To do so, we fitted linear and piecewise linear regression and a regime shift model to the time series of mean annual values of each variable and to principal components produced by Principal Component Analysis. Models were weighted and ranked using Akaike information criterion and the model selection approach. Most environmental variables exhibited temporal changes that included time-varying trends and trend reversals. For instance, dissolved organic carbon showed a linear increasing trend while nitrate concentration or conductivity exemplified trend reversal. All trend reversals and cessations of temporal trends in reservoir hydrochemistry (except total phosphorus concentrations) occurred in the late 1980s and during 1990s as a consequence of dramatic socioeconomic changes. After a series of heavy rains in the late 1990s, an administrative decision to increase the flood-retention volume of the reservoir resulted in a significant regime shift in reservoir hydraulic conditions in 1999. Our analyses also highlight the utility of the model selection framework, based on relatively simple extensions of linear regression, to describe temporal trends in reservoir characteristics. This approach can

Forty-Year Trends in Cholangiocarcinoma Incidence in the U.S.: Intrahepatic Disease on the Rise.

PubMed

Saha, Supriya K; Zhu, Andrew X; Fuchs, Charles S; Brooks, Gabriel A

2016-05-01

Challenges in the diagnosis and classification of cholangiocarcinoma have made it difficult to quantify the true incidence of this highly aggressive malignancy. We analyzed the Surveillance, Epidemiology, and End Results data to assess long-term trends in the age-standardized incidence of intrahepatic and extrahepatic cholangiocarcinoma between 1973 and 2012, correcting for systematic coding errors. Because intrahepatic cholangiocarcinoma (ICC) may frequently be misdiagnosed as cancer of unknown primary (CUP), we also analyzed trends in the incidence of CUP. Between 1973 and 2012, the reported U.S. incidence of ICC increased from 0.44 to 1.18 cases per 100,000, representing an annual percentage change (APC) of 2.30%; this trend has accelerated during the past decade to an APC of 4.36%. The incidence of extrahepatic cholangiocarcinoma increased modestly from 0.95 to 1.02 per 100,000 during the 40-year period (APC, 0.14%). The incidence of CUP with histologic features potentially consistent with cholangiocarcinoma decreased by 51% between 1973 and 2012 (APC, -1.87%), whereas the incidence of CUP with squamous or nonepithelial histologic features increased modestly (APC, 0.42%). The recognized incidence of ICC in the U.S. continues to rise, whereas the incidence of ECC is stable. The incidence of CUP has fallen dramatically during the same time period. Clinical distinctions between cholangiocarcinoma (particularly intrahepatic cholangiocarcinoma [ICC]) and cancer of unknown primary (CUP) can be challenging. Recent discoveries have identified recurrent and potentially targetable genomic abnormalities in ICC, highlighting the importance of improving diagnosis. This study demonstrates that the incidence of ICC is increasing in the U.S., whereas the incidence of extrahepatic cholangiocarcinoma is stable. Concomitantly, the incidence of CUP has declined dramatically, suggesting that improved distinction between ICC and CUP may be a major driver of the increasing recognized

Educational Development in China: Characteristics and Trends.

ERIC Educational Resources Information Center

Lamontagne, Jacques

Some characteristics and trends of the educational development in the People's Republic of China (PRC) are analyzed on the basis of statistical data covering the period 1949 to 1985. During the 1950s, 1960s, and 1970s, the educational development of the PRC displayed a trend toward the reduction of educational disparities among regions and among…

Interferometric Imaging of Titan’s HC3N, H13CCCN, and HCCC15N

NASA Astrophysics Data System (ADS)

Cordiner, M. A.; Nixon, C. A.; Charnley, S. B.; Teanby, N. A.; Molter, E. M.; Kisiel, Z.; Vuitton, V.

2018-05-01

We present the first maps of cyanoacetylene isotopologues in Titan’s atmosphere, including H13CCCN and HCCC15N, detected in the 0.9 mm band using the Atacama Large Millimeter/submillimeter array (ALMA) around the time of Titan’s (southern winter) solstice in 2017 May. The first high-resolution map of HC3N in its v 7 = 1 vibrationally excited state is also presented, revealing a unique snapshot of the global HC3N distribution, free from the strong optical depth effects that adversely impact the ground-state (v = 0) map. The HC3N emission is found to be strongly enhanced over Titan’s south pole (by a factor of 5.7 compared to the north pole), consistent with rapid photochemical loss of HC3N from the summer hemisphere combined with production and transport to the winter pole since the 2015 April ALMA observations. The H13CCCN/HCCC15N flux ratio is derived at the southern HC3N peak, and implies an HC3N/HCCC15N ratio of 67 ± 14. This represents a significant enrichment in 15N compared with Titan’s main molecular nitrogen reservoir, which has a 14N/15N ratio of 167, and confirms the importance of photochemistry in determining the nitrogen isotopic ratio in Titan’s organic inventory.

Detection and attribution of nitrogen runoff trend in China's croplands.

PubMed

Hou, Xikang; Zhan, Xiaoying; Zhou, Feng; Yan, Xiaoyuan; Gu, Baojing; Reis, Stefan; Wu, Yali; Liu, Hongbin; Piao, Shilong; Tang, Yanhong

2018-03-01

Reliable detection and attribution of changes in nitrogen (N) runoff from croplands are essential for designing efficient, sustainable N management strategies for future. Despite the recognition that excess N runoff poses a risk of aquatic eutrophication, large-scale, spatially detailed N runoff trends and their drivers remain poorly understood in China. Based on data comprising 535 site-years from 100 sites across China's croplands, we developed a data-driven upscaling model and a new simplified attribution approach to detect and attribute N runoff trends during the period of 1990-2012. Our results show that N runoff has increased by 46% for rice paddy fields and 31% for upland areas since 1990. However, we acknowledge that the upscaling model is subject to large uncertainties (20% and 40% as coefficient of variation of N runoff, respectively). At national scale, increased fertilizer application was identified as the most likely driver of the N runoff trend, while decreased irrigation levels offset to some extent the impact of fertilization increases. In southern China, the increasing trend of upland N runoff can be attributed to the growth in N runoff rates. Our results suggested that increased SOM led to the N runoff rate growth for uplands, but led to a decline for rice paddy fields. In combination, these results imply that improving management approaches for both N fertilizer use and irrigation is urgently required for mitigating agricultural N runoff in China. Copyright © 2017 Elsevier Ltd. All rights reserved.

S&T converging trends in dealing with disaster: A review on AI tools

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hasan, Abu Bakar, E-mail: abakarh@usim.edu.my; Isa, Mohd Hafez Mohd.

Science and Technology (S&T) has been able to help mankind to solve or minimize problems when arise. Different methodologies, techniques and tools were developed or used for specific cases by researchers, engineers, scientists throughout the world, and numerous papers and articles have been written by them. Nine selected cases such as flash flood, earthquakes, workplace accident, fault in aircraft industry, seismic vulnerability, disaster mitigation and management, and early fault detection in nuclear industry have been studied. This paper looked at those cases, and their results showed nearly 60% uses artificial intelligence (AI) as a tool. This paper also did somemore » review that will help young researchers in deciding the types of AI tools to be selected; thus proving the future trends in S&T.« less

Trends in Snacking Among U.S. Children

PubMed Central

2010-01-01

Nationally representative surveys of food intake in US children show large snacking increases between the 1989–91 to 1994–98 and 1994–98 to 2003–06 periods. Childhood snacking trends are moving toward three snacks per day with over 27% of daily calories coming from snacks. The largest increases have been in salty snack and candy consumption, while desserts and sweetened beverages remain the major sources of calories from snacks. PMID:20194979

N1N8-bis(gamma-glutamyl)spermidine cross-linking in epidermal-cell envelopes. Comparison of cross-link levels in normal and psoriatic cell envelopes.

PubMed Central

Martinet, N; Beninati, S; Nigra, T P; Folk, J E

1990-01-01

N1N8-Bis(gamma-glutamyl)spermidine was found in exhaustive proteolytic digests of isolated cell envelopes from human epidermis at levels comparable with those of epsilon-(gamma-glutamyl)lysine. Significantly higher than normal amounts of these compounds, particularly the bis(gamma-glutamyl)polyamine, were observed in envelopes from afflicted areas (scales) of psoriatic patients. These findings support the notions that N1N8-bis(gamma-glutamyl)spermidine, like epsilon-(gamma-glutamyl)lysine, functions in cell envelopes as an enzyme-generated protein cross-link and stabilizing force and that individuals with the chronic, recurrent skin disease, psoriasis, exhibit in involved epidermis abnormal cell-envelope-protein cross-linking. PMID:2241917

Catalytic growth of vertically aligned SnS/SnS2 p-n heterojunctions

NASA Astrophysics Data System (ADS)

Degrauw, Aaron; Armstrong, Rebekka; Rahman, Ajara A.; Ogle, Jonathan; Whittaker-Brooks, Luisa

2017-09-01

Nanowire arrays of SnS/SnS2 p-n heterojunctions are grown on transparent indium tin oxide (ITO) coated-glass and Si/SiO2 substrates via chemical vapor transport (CVT). The nanowire arrays are comprised of individual SnS/SnS2 heterostructures that are highly oriented with their lengths and morphologies controlled by the CVT conditions (i.e. reaction temperature, flow rate, and reaction time). The growth and optoelectronic characterization of these well-defined SnS/SnS2 p-n heterostructures pave the way for the fabrication of highly efficient solar cell devices.

Poly(N-arylenebenzimidazole)s via aromatic nucleophilic displacement

NASA Technical Reports Server (NTRS)

Connell, John W. (Inventor); Hergenrother, Paul M. (Inventor); Smith, Jr., Joseph G. (Inventor)

1996-01-01

Novel poly(N-arylenebenzimidazole)s (PNABls) are prepared by the aromatic nucleophilic displacement reaction of novel di(hydroxyphenyl-N-arylene benzimidazole) monomers with activated aromatic dihalides or activated aromatic dinitro compounds. The polymerizations are carried out in polar aprotic solvents such as N-methyl-2-pyrrolidinone or N,N-dimethylacetamide using alkali metal bases such as potassium carbonate at elevated temperatures under nitrogen. The di(hydroxyphenyl-N-arylenebenzimidazole) monomers are synthesized by reacting phenyl-4-hydroxybenzoate with bis(2-aminoanilino)arylenes in diphenylsulfone. Moderate molecular weight PNABIs of new chemical structures were prepared that exhibit a favorable combination of physical and mechanical properties. The use of the novel di(hydroxyphenyI-N-arylenebenzimidazole)s permits a more economical and easier way to prepare PNABIs than previous routes.

Extrapolation of astrophysical S factors for the reaction {sup 14}N((p, {gamma}) {sup 15}O to near-zero energies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Artemov, S. V.; Igamov, S. B., E-mail: igamov@inp.uz; Tursunmakhatov, Q. I.

2012-03-15

The astrophysical S factors for the radiative-capture reaction {sup 14}N(p, {gamma}){sup 15}O in the region of ultralow energies were calculated on the basis of the R-matrix approach. The values of the radiative and protonic widths were fitted to new experimental data. The contribution of direct radiative capture to bound states of the {sup 15}O nucleus was determined with the aid of asymptotic normalization coefficients, whose values were refined in the present study on the basis of the results obtained from an analysis of the reaction {sup 14}N({sup 3}He, d){sup 15}O at three different energies of incident helium ions. A valuemore » of S(0) = 1.79 {+-} 0.31 keV b was obtained for the total astrophysical S factor, and the reaction rate was determined for the process {sup 14}N(p, {gamma}){sup 15}O.« less

Ten power mega-trends for the 1990`s

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zimmer, M.J.

1995-12-01

Changes in the power generation industry have accelerated, with the progress of new legislation, globalization, financing and technology leading the way. Major trends shaping the future of the industry this decade include: fuels; niche markets; utility generation; financing; retail service; transmission; geographic regions; repowering; international developments; and regulation. These factors are discussed briefly.

Andreev reflection in monolayer MoS2

NASA Astrophysics Data System (ADS)

Majidi, Leyla; Rostami, Habib; Asgari, Reza

2014-01-01

Andreev reflection in a monolayer molybdenum disulfide superconducting-normal (S/N) hybrid junction is investigated. We find, by using a modified Dirac Hamiltonian and the scattering formalism, that the perfect Andreev reflection happens at normal incidence with p-doped S and N regions. The probability of the Andreev reflection and the resulting Andreev conductance, in this system, are demonstrated to be large in comparison with the corresponding gapped graphene structure. We further investigate the effect of a topological term (β ) in the Hamiltonian and show that it results in an enhancement of the Andreev conductance with p-doped S and N regions, while in the corresponding structure with an n-doped S region it is strongly reducible in comparison. This effect can be explained in terms of the dependence of the Andreev reflection probability on the sign of β and the chemical potential in the superconducting region.

AIRS Water Vapor and Cloud Products Validate and Explain Recent Negative Global and Tropical OLR Trends Observed by CERES

NASA Technical Reports Server (NTRS)

Susskind, Joel; Molnar, Gyula; Iredell, Lena

2010-01-01

This paper compares spatial and temporal anomalies and trends of OLR as observed by CERES and computed based on AIRS retrieved surface and atmospheric geophysical parameters over the time period September 2002 February 2010. This time period is marked by a substantial decreasing OLR trend on the order of -0.1 W/m2/yr averaged over the globe. There are very large spatial variations of these trends however, with local values ranging from -2.6 W/m2/yr to +3.0 W/m2/yr in the tropics. The spatial patterns of the AIRS and CERES trends are in essentially perfect agreement with each other, as are the anomaly time series averaged over different spatial regions. This essentially perfect agreement of OLR anomalies and trends derived from observations by two different instruments, in totally independent and different manners, implies that both sets of results must be highly accurate. The agreement of anomalies and trends of OLR as observed by CERES and computed from AIRS derived products also indirectly validates the anomalies and trends of the AIRS derived products as well. We used the anomalies and trends of AIRS derived water vapor and cloud products to explain why global OLR has had a large negative trend over the time period September 2002 through February 2010. Tropical OLR began to decrease significantly at the onset of a strong La Nina in mid-2007. AIRS products show that cloudiness and mid-tropospheric water vapor began to increase in the region 5degN - 20degS latitude extending eastward from 150degW - 30 E longitude at that time, with a corresponding very large drop in OLR in this region. Late 2009 is characterized by a strong El-Nino, with a corresponding change in sign of observed anomalies of mid-tropospheric water vapor, cloud cover, and OLR in this region, as we] l as that of OLR anomalies in the tropics and globally. Monthly mean anomalies of OLR, water vapor and cloud cover over this region are all shown to be highly correlated in time with those of an El Nino

Status and Trends in U.S. Compliance and Voluntary Renewable Energy Certificate Markets (2010 Data)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heeter, J.; Bird, L.

2011-10-01

This report documents the status and trends of 'compliance'--renewable energy certificate (REC) markets used to meet state renewable portfolio standard (RPS) requirements--and 'voluntary' markets--those in which consumers and institutions purchase renewable energy to match their electricity needs on a voluntary basis. Today, 29 states and the District of Columbia have an RPS, more than half of all U.S. electricity customers have an option to purchase some type of green power product directly from a retail electricity provider, and all consumers have the option to purchase RECs. This report documents REC activities and trends in the United States. The compliance RECmore » market analysis includes analysis of REC trading, regional REC markets, REC tracking systems, types of compliance RECs, compliance REC pricing trends, and an overview of compliance with RPS polices. The voluntary REC analysis presents data and analysis on voluntary market sales and customer participation, products and premiums, green pricing marketing and administrative expenses, voluntary REC pricing, and the voluntary carbon offsets market. The report concludes with a discussion of upcoming guidance from the Federal Trade Commission on green marketing claims, the emergence of community solar programs, and the potential impact of Dodd-Frank regulations on the REC market.« less

TEM study of the (SbS){sub 1+δ}(NbS{sub 2}){sub n}, (n=1, 2, 3; δ~1.14, 1.20) misfit layer phases

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gómez-Herrero, A., E-mail: adriangh@pdi.ucm.es; Landa-Cánovas, A.R.; Otero-Díaz, L.C.

In the Sb–Nb–S system four new misfit layer phases have been found and carefully investigated via Transmission Electron Microscopy (TEM). Their structures are of composite modulated structure type with stoichiometries that can be formulated as (SbS){sub 1+δ}(NbS{sub 2}){sub n}; for n=1, δ~1.14 and 1.19; for n=2, δ~1.18 and for n=3, δ~1.19. Selected Area Electron Diffraction (SAED) patterns show an almost commensurate fit between the pseudo-tetragonal (SbS) and the pseudo-orthohexagonal (NbS{sub 2}){sub n} subcells along the misfit direction a, with 3(SbS)≈5(NbS{sub 2}), being b the same for both sub-lattices and c the stacking direction. For n=1, a commensurate phase with 4a{submore » SbS}=7a{sub NbS2} has also been observed. In addition to the characteristic misfit and associated modulation of the two sub-structures, a second modulation is also present which appears to be primarily associated with the (SbS) sub-structure of both the n=1 and n=2 phases. High Resolution Transmission Electron Microscopy (HRTEM) images show ordered stacking sequences between the (SbS) and (NbS{sub 2}){sub n} lamellae for each of the four phases, however, disordered intergrowths were also occasionally found. Most of the crystals showed different kinds of twinning defects on quite a fine scale. Many crystals showed curled up edges. In some cases the lamellar crystals were entirely folded giving rise to similar diffraction patterns as found for cylindrical crystals. - Graphical abstract: Idealized structure models of the first three members of the homologous series (SbS){sub 1+δ}(NbS{sub 2}){sub n}. - Highlights: • Transmission Electron Microscopy study of misfit layer sulfides (SbS){sub 1+δ}(NbS{sub 2}){sub n}. • The structures consist of a (SbS) layer interleaved between n (NbS{sub 2}) layers. • Two different members n=1, one n=2 and one n=3 have been studied. • Twinning, intergrowths and different modulations in the (SbS) substructure.« less

Mineral exploration and fracture trends in Utah and Nevada, by ERTS-1 imagery

NASA Technical Reports Server (NTRS)

Jensen, M. L. (Principal Investigator); Smith, M. R.

1973-01-01

The author has identified the following significant results. Major structural trends have been compiled on five separate maps, at a scale of 1:1,000,000, of Utah and Nevada from ERTS-1 imagery. An arbitrary length of ten kilometers has been chosen as a minimum length of the trends. The selection is based upon: (1) obvious displacement of structures; (2) continuity or persistence of trends across structures; (3) line-up of outcrop patterns, drainage, erosional features or vegetation; and (4) near-linear trends. Several recognizable trend directions have noted, viz., N 10-15 deg W, N 35 deg W, N 80 deg W, N 30 deg E, and E-W. More than 1500 structural trends have been identified, some of which are mineralized and extend into pediment or shallow alluvial cover. Those fracture trends that exhibit mineralization in exposed bedrock will be assayed for mercury content with a soil-gas analyzer and similar collection will be done over alluvial posture blankets by the same technique with the hope of discovering blind mineralized zones that are not exposed on the surface.

Determinants and Temporal Trends of Perfluoroalkyl Substances in Pregnant Women: The Hokkaido Study on Environment and Children’s Health

PubMed Central

Tsai, Meng-Shan; Miyashita, Chihiro; Itoh, Sachiko; Bamai, Yu Ait; Goudarzi, Houman; Okada, Emiko; Kashino, Ikuko; Matsuura, Hideyuki; Kishi, Reiko

2018-01-01

Perfluoroalkyl substances (PFAS) are persistent bio-accumulative chemicals that impact the health of pregnant women and their children. PFAS derive from environmental and consumer products, which depend on human lifestyle, socioeconomic characteristics, and time variation. Here, we aimed to explore the temporal trends of PFAS in pregnant women and the characteristics related to maternal PFAS concentration. Our study is part of the Hokkaido Study on Environment and Children’s Health, the Hokkaido large-scale cohort that recruited pregnant women between 2003 and 2011. Blood samples were acquired from pregnant women during the third trimester to measure PFAS and cotinine concentrations. Maternal basic information was collected with a baseline structured questionnaire. Eleven PFAS were measured from 2123 samples with ultra-performance liquid chromatography coupled with triple quadrupole tandem mass spectrometry. Eight PFAS were above 80% detection rate and were included in the final analysis. We used multivariable linear regression to analyze the association of pregnant women characteristics with the levels of eight PFAS. The temporal trend of PFAS was observed in two periods (August 2003 to January 2006 and February 2006 to July 2012). The concentration of perfluorooctane sulfonate (PFOS) significantly decreased from August 2003 to January 2006 and from February 2006 to July 2012. The concentrations of perfluorododecanoic acid (PFDoDA), perfluoroundecanoic acid (PFUnDA), and perfluorotridecanoic acid (PFTrDA) increased significantly between August 2003 and January 2006, whereas they decreased significantly between February 2006 and July 2012. Women with pre-pregnancy body mass index (BMI) >25 kg/m2 had lower PFUnDA, PFDoDA, and PFTrDA levels than did those with normal BMI (18.5–24.9 kg/m2). Pregnant women, who were active smokers (cotinine > 11.49 ng/mL), had higher PFOS than the non-smokers (cotinine < 0.22 ng/mL). Lower levels of PFHxS, PFOS, PFOA, PFNA, and

Pair-breaking mechanisms in superconductor—normal-metal—superconductor junctions

NASA Astrophysics Data System (ADS)

Yang, H. C.; Finnemore, D. K.

1984-08-01

The critical current density Jc has been measured for superconductor—normal-metal—superconductor (S-N-S) junctions over a wide range of temperature and composition in order to determine the depairing effects of magnetic impurities. Junctions, which are in a sandwich geometry with the N layer typically 600 nm thick, show well-defined diffraction patterns indicating that the junctions are of high quality. Below 4.2 K, the temperature dependence of Jc is found to follow a modified bridge theory based on the work of Makeev et al.

Recent Trends in Multiple Authorship in Psychology.

ERIC Educational Resources Information Center

Mendenhall, Mark; Higbee, Kenneth L.

Research in the late 1950's showed a trend towards increased multiple authorship, as opposed to single authorship, of research papers in psychology. To investigate whether the trend has continued into the 1980's, convention papers presented at the meetings of seven psychological associations and articles published in nine American Psychological…

Physical nature of the [S II]-bright shell nebulae N70 and N185

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Ning-Xiao; Jiang, Bing; Chen, Yang

2014-09-01

N70 and N185 are two large (≥100 pc in diameter) shell nebulae in the Large Magellanic Cloud (LMC). Their high [S II]/Hα ratios rival those of supernova remnants (SNRs), but they are not confirmed as SNRs. To study their physical nature, we have obtained XMM-Newton X-ray observations and high-dispersion long-slit echelle spectroscopic observations of these two nebulae. The X-ray spectra of both nebulae can be well interpreted with an optically thin thermal (∼0.2 keV) plasma with the average LMC abundance in a collisional ionization equilibrium. N70 encompasses the OB association LH114. Although N70 has a modest expansion velocity and essentiallymore » thermal radio emission, its diffuse X-ray luminosity (∼6.1 × 10{sup 35} erg s{sup –1}) is higher than that from a quiescent superbubble with N70's density, size, and expansion velocity; thus, N70 is most likely a superbubble that is recently energized by an interior SNR. N185 does not contain any known OB association, and its X-ray luminosity is an order of magnitude lower than expected if it is a quiescent superbubble. N185 has nonthermal radio emission and has high-velocity material expanding at nearly 200 km s{sup –1}, similar to many known SNRs in the LMC. Its X-ray luminosity (∼1.9 × 10{sup 35} erg s{sup –1}) is also consistent with that of an evolved SNR. We therefore suggest that N185 is energized by a recent supernova.« less

Trends in disability and program participation among U.S. veterans.

PubMed

Ben-Shalom, Yonatan; Tennant, Jennifer R; Stapleton, David C

2016-07-01

Disability is increasingly part of the lives of veterans and more research is needed to understand its impact on veterans' participation in disability benefit programs. We examine how recent trends in receipt of service-connected disability compensation from the Department of Veterans Affairs (VA) compare to trends in self-reported disability and participation in Social Security Disability Insurance (DI) and Supplemental Security Income (SSI) among veterans. We use 2002-2013 data from the Current Population Survey to describe trends in receipt of VA disability compensation and to compare between trends in self-reported disability and DI/SSI participation for veterans versus nonveterans. The percentage of veterans reporting they receive VA disability compensation increased substantially from 2002 to 2013 and was especially notable among younger (ages 18-39) and older (ages 50-64) veterans. From 2009 to 2013, self-reported disability increased among the younger and older veterans but not among middle-age veterans and nonveterans, and self-reported cognitive disability increased substantially among young veterans. DI/SSI participation among older veterans increased more than for nonveterans over the period examined. Effective policies are needed to incentivize work among young veterans and to help them obtain both the skills they need to succeed in the labor force and the supports (such as psychiatric health services) they need to do so. Older veterans are facing increasing challenges in the labor market, and further research is needed to determine whether these challenges are primarily related to health, a growing skills gap, or poorly-aligned incentives. Copyright © 2016 Elsevier Inc. All rights reserved.

Normal state above the upper critical field in Fe 1 + y Te 1 - x ( Se , S ) x

DOE PAGES

Wang, Aifeng; Kampert, Erik; Saadaoui, H.; ...

2017-05-03

Here, we have investigated the magnetotransport above the upper critical field ( H c 2 ) in Fe 1.14 Te 0.7 Se 0.3 , Fe 1.02 Te 0.61 Se 0.39 , Fe 1.05 Te 0.89 Se 0.11 , and Fe 1.06 Te 0.86 S 0.14 . The μ SR measurements confirm electronic phase separation in Fe 1.06 Te 0.86 S 0.14 , similar to Fe 1 + y Te 1 - x Se x . We found that superconductivity is suppressed in high magnetic fields above 60 T, allowing us to gain insight into the normal-state properties below the zero-fieldmore » superconducting transition temperature ( T c ). We also show that the resistivity of Fe 1.14 Te 0.7 Se 0.3 and Fe 1.02 Te 0.61 Se 0.39 above H c 2 is metallic as T → 0 , just like the normal-state resistivity above T c . On the other hand, the normal-state resistivity in Fe 1.05 Te 0.89 Se 0.11 and Fe 1.06 Te 0.86 S 0.14 is nonmetallic down to lowest temperatures, reflecting the superconductor-insulator transition due to electronic phase separation.« less

Development of Miocene-Pliocene reef trend, St. Croix, U. S. Virgin Islands

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gill, I.; Eby, D.E.; Hubbard, D.K.

1988-01-01

The Miocene-Pliocene reef trend on St. Croix, U.S. Virgin Islands, rims the present southern western coasts of the island and includes accompanying lagoonal and forereef facies. The reef trend was established on a foram-algal bank facies that represents basinal shallowing from the deep-water pelagic and hemipelagic facies of the Miocene Kingshill Limestone. Information on facies distribution and thickness is derived from rock exposures and 22 test wells drilled to a maximum depth of 91 m. The greatest thickness of the reef facies exists in a subsidiary graben on the south coast of St. Croix. The thickness of the reef sectionmore » in this locality is due to preservation of the section in a downdropped block. Reef faunas include extant corals, as well as several extinct genera. Extant corals (e.g. Montastrea annularis, Diploria sp., and Porites porites) and extinct corals (e.g., Stylophora affinis, Antillea bilobata, and Thysanus sp.) are the main reef frame-builders. Coralline algea and large benthic foraminifera are significant contributors to the sediments both prior to and during scleractinian reef growth. Dolomitization and calcite cementation occur prominantly in an area corresponding to a Holocene lagoon. The spatial distribution of the dolomite suggests that the lagoon is a Tertiary feature directly related to the dolomitization process. Stable isotopic values suggest dolomitization of fluids of elevated salinity.« less

Study of poly(N,N-dimethylacrylamide)/CdS nanocomposite organic/inorganic gels.

PubMed

Bekiari, Vlasoula; Pagonis, Konstantinos; Bokias, Georgios; Lianos, Panagiotis

2004-09-14

CdS nanoparticles have been synthesized and stabilized in poly(N,N-dimethylacrylamide) hydrogels. The properties of the composite material have been characterized by UV-vis spectroscopy, scanning electron microscopy, X-ray diffraction, thermogravimetric analysis, and steady-state and time-resolved luminescence spectroscopy. This material can be obtained in three different states: swollen, shrunk, and freeze-dried. The swollen and the freeze-dried states correspond to a nanocomposite organic/inorganic (wet or dry) gel containing CdS nanoparticles of approximately 50 nm diameter while the shrunk state is a two-phase system containing CdS crystals, which precipitate forming interesting geometrical shapes.

Trends in Classroom Observation Scores

ERIC Educational Resources Information Center

Casabianca, Jodi M.; Lockwood, J. R.; McCaffrey, Daniel F.

2015-01-01

Observations and ratings of classroom teaching and interactions collected over time are susceptible to trends in both the quality of instruction and rater behavior. These trends have potential implications for inferences about teaching and for study design. We use scores on the Classroom Assessment Scoring System-Secondary (CLASS-S) protocol from…

N = 2 S-duality revisited

NASA Astrophysics Data System (ADS)

Buican, Matthew; Laczko, Zoltan; Nishinaka, Takahiro

2017-09-01

Using the chiral algebra bootstrap, we revisit the simplest Argyres-Douglas (AD) generalization of Argyres-Seiberg S-duality. We argue that the exotic AD superconformal field theory (SCFT), T_{3,3/2} , emerging in this duality splits into a free piece and an interacting piece, T_X , even though this factorization seems invisible in the Seiberg-Witten (SW) curve derived from the corresponding M5-brane construction. Without a Lagrangian, an associated topological field theory, a BPS spectrum, or even an SW curve, we nonetheless obtain exact information about T_X by bootstrapping its chiral algebra, {}_X(T_X) , and finding the corresponding vacuum character in terms of Affine Kac-Moody characters. By a standard 4D/2D correspondence, this result gives us the Schur index for T_X and, by studying this quantity in the limit of small S 1, we make contact with a proposed S 1 reduction. Along the way, we discuss various properties of T_X : as an N = 1 theory, it has flavor symmetry SU(3) × SU(2) × U(1), the central charge of {}_X(T_X) matches the central charge of the bc ghosts in bosonic string theory, and its global SU(2) symmetry has a Witten anomaly. This anomaly does not prevent us from building conformal manifolds out of arbitrary numbers of T_X theories (giving us a surprisingly close AD relative of Gaiotto's T N theories), but it does lead to some open questions in the context of the chiral algebra/4D N =2SCFT correspondence.

Selectivity trend of gas separation through nanoporous graphene

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu, Hongjun; Chen, Zhongfang; Dai, Sheng

2014-01-29

We demonstrate that porous graphene can efficiently separate gases according to their molecular sizes using molecular dynamic (MD) simulations,. The flux sequence from the classical MD simulation is H 2>CO 2>>N 2>Ar>CH 4, which generally follows the trend in the kinetic diameters. Moreover, this trend is also confirmed from the fluxes based on the computed free energy barriers for gas permeation using the umbrella sampling method and kinetic theory of gases. Both brute-force MD simulations and free-energy calcualtions lead to the flux trend consistent with experiments. Case studies of two compositions of CO 2/N 2 mixtures further demonstrate the separationmore » capability of nanoporous graphene.« less

Novel Data Sources for Women’s Health Research: Mapping Breast Screening Online Information Seeking Through Google Trends

PubMed Central

Dehkordy, Soudabeh Fazeli; Carlos, Ruth C.; Hall, Kelli S.; Dalton, Vanessa K.

2015-01-01

Rationale and Objectives Millions of people use online search engines every day to find health-related information and voluntarily share their personal health status and behaviors in various Web sites. Thus, data from tracking of online information seeker’s behavior offer potential opportunities for use in public health surveillance and research. Google Trends is a feature of Google which allows internet users to graph the frequency of searches for a single term or phrase over time or by geographic region. We used Google Trends to describe patterns of information seeking behavior in the subject of dense breasts and to examine their correlation with the passage or introduction of dense breast notification legislation. Materials and Methods In order to capture the temporal variations of information seeking about dense breasts, the web search query “dense breast” was entered in the Google Trends tool. We then mapped the dates of legislative actions regarding dense breasts that received widespread coverage in the lay media to information seeking trends about dense breasts over time. Results Newsworthy events and legislative actions appear to correlate well with peaks in search volume of “dense breast”. Geographic regions with the highest search volumes have either passed, denied, or are currently considering the dense breast legislation. Conclusions Our study demonstrated that any legislative action and respective news coverage correlate with increase in information seeking for “dense breast” on Google, suggesting that Google Trends has the potential to serve as a data source for policy-relevant research. PMID:24998689

Measurement of Religiosity/Spirituality in Adolescent Health Outcomes Research: Trends and Recommendations

PubMed Central

McGrady, Meghan E.; Rosenthal, Susan L.

2010-01-01

The relationship between religious/spiritual (R/S) factors and adolescent health outcomes has been studied for decades; however, the R/S measurement tools used may not be developmentally relevant for adolescents. A systematic literature review was conducted to review and evaluate trends in measuring R/S in adolescent health outcomes research. In this review a total of 100 articles met criteria for inclusion. Relatively few (n = 15) included adolescent-specific R/S measures or items accounting for developmentally relevant issues such as parental religiosity or age-appropriate language. Future R/S and health research with adolescents would be strengthened by incorporating developmentally relevant R/S measurement tools, psychometrics, and multidimensional measures. PMID:20127172

A.N. Kolmogorov’s defence of Mendelism

PubMed Central

Stark, Alan; Seneta, Eugene

2011-01-01

In 1939 N.I. Ermolaeva published the results of an experiment which repeated parts of Mendel’s classical experiments. On the basis of her experiment she concluded that Mendel’s principle that self-pollination of hybrid plants gave rise to segregation proportions 3:1 was false. The great probability theorist A.N. Kolmogorov reviewed Ermolaeva’s data using a test, now referred to as Kolmogorov’s, or Kolmogorov-Smirnov, test, which he had proposed in 1933. He found, contrary to Ermolaeva, that her results clearly confirmed Mendel’s principle. This paper shows that there were methodological flaws in Kolmogorov’s statistical analysis and presents a substantially adjusted approach, which confirms his conclusions. Some historical commentary on the Lysenko-era background is given, to illuminate the relationship of the disciplines of genetics and statistics in the struggle against the prevailing politically-correct pseudoscience in the Soviet Union. There is a Brazilian connection through the person of Th. Dobzhansky. PMID:21734813

Secular trends in overweight and obesity among Icelandic adolescents: do parental education levels and family structure play a part?

PubMed

Eidsdóttir, Sigridur Þ; Kristjánsson, Álfgeir l; Sigfúsdóttir, Inga D; Garber, Carol E; Allegrante, John P

2013-06-01

To investigate whether the secular trend in the increasing prevalence of overweight and obesity among 16- to 20-year-old adolescents in Iceland varied by levels of parental education and family structure. Odds ratios were calculated from repeated population-based, cross-sectional surveys comprising cohorts of 16- to 20-year-old Icelandic adolescents attending junior colleges in 1992 (n=4,922), 2004 (n=11,031), 2007 (n=11,229), and 2010 (n=11,388). Body mass index (BMI) was calculated from self-reported weight and height and categorised as normal weight or overweight and obese, and examined in relation to parental education level and family structure. The odds of being overweight increased by 2.62 and 1.71 for boys and girls respectively over each of the survey time points. The prevalence of overweight and obesity increased across all three subgroups (low, medium, and high) of parental education level. The probability of overweight across all years were consistently the highest for youths with parents in the low-education category followed by middle-educated and high-educated parental background (p<0.05). The gap in overweight and obesity trends between respondents' parental education backgrounds increased over time and was generally explained more by the fathers' education than by the mothers' education (p<0.05). Family structure was not associated with the prevalence of overweight and obesity in our data. Differences in parental levels of education are associated with accelerating trends in prevalence of overweight and obesity among 16- to 20-year-old adolescents in Iceland.

Comparative pharmacokinetics of (S)-MP3950, a novel 5-HT4 receptor agonist, in normal and atropine-induced gastrointestinal motility disorders rats.

PubMed

Wang, Binjie; Sun, Xiaoyang; Wang, Shixiao; Guo, Ping; Li, Shujuan; Zhang, Meiyu; Zhao, Longshan; Chen, Xiaohui

2018-08-01

1. (S)-MP3950 is the (S)-enantiomer of active metabolite of mosapride, which exhibits higher 5-HT 4 receptor agonistic effect than mosapride. It shows promise to become a novel drug candidate for the treatment of gastrointestinal motility disorders (GMDs). However, the pharmacokinetic behavior of (S)-MP3950 in the pathological state of GMDs remains unclear. Herein, we investigated the comparative pharmacokinetics of (S)-MP3950 in normal and GMDs rats. 2. The comparative pharmacokinetics of (S)-MP3950 in normal and atropine-induced GMD rats were studied by ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The validated UPLC-MS/MS method was successfully applied to investigate the pharmacokinetic profiles of (S)-MP3950 in normal and atropine-induced GMDs rats. Results showed that comparing to normal rats, C max reduced by 73.8%, AUC 0-t decreased by 57.6% and AUC 0-∞ declined by 56.8% in model rats. Additionally, the elimination half-life (t 1/2 ) and T max were prolonged slightly. 3. The pharmacokinetic results demonstrated that the atropine-induced GMDs reduced the absorption of (S)-MP3950. The pharmacokinetics research in the pathological state might provide more useful information for further study of novel gastric motility candidates.

Reproductive behaviour in the 1980s: Europe revisited. Council of Europe: an account of the work of a committee of experts on fertility trends.

PubMed

Deven, F

1985-01-01

This article highlights the findings of a 3-stage analysis conducted in 1982-85 by the Council of Europe Committee of Experts on Fertility Trends: The 1st phase involved a demographic analysis of reproductive behavior in the past decade, the 2nd focused on the background of recent fertility trends, and the 3rd examined possible consequences of these trends. Participating countries included Belgium, France, Federal Republic of Germany, Luxembourg, the Netherlands, Norway, Portugal, Spain, and Switzerland. During the 1970s; most of these countries experienced a continuation of the fertility decline begun in the mid-60s, resulting in the large majority of countries in below-replacement reproduction. In general, the effect of the fertility decline on the birth rate has been partially compensated by the favorable age structure of the reproductive age population. In the 1st half of the 1970s, both nuptiality and reproductive behavior in marriage contributed to the fertility decline; in the 2nd half, marital fertility showed increases. The fertility decline in the 1st half of the 1970s largely reflected the steep decline in fertility among younger age groups, whereas a rise in the fertility in the older age groups was a characteristic of the late 1970s. However, the stabilization or even slight increase in fertility noted in the late 1970s in several European countries reverted to a decline in the early 1980s. In general, small family size appears to be viewed as a good compromise between pyschological and economic costs and benefits. These low fertility trends have had a dramatic effect on household composition and have also facilitated women's personal growth and economic independence. These trends are expected to lead to demographic aging of the population and alleviation of pressures on the labor market. All such changes will require adaptive population policy measures. It is important that such policies do not endanger achievements of modernization such as human

The a´ velocity in the tissue Doppler predicts S/D ratio <1 in patients with a normal ejection fraction.

PubMed

Johansson, Benny; Lundin, Fredrik; Tegeback, Rolf; Bojö, Leif

2018-04-13

To compare the ability of the a´ velocity and the e´ velocity in predicting a dominant diastolic pulmonary vein flow (S/D ratio <1) in patients with normal ejection fraction. We retrospectively evaluated the diastolic function according to the ASE/EACVI guidelines, the S/D ratio and the septal, lateral and average a´ velocity in 293 unselected in-hospital patients, aged 39-86 years, in sinus rhythm and with no or mild valve disease, having a normal systolic function (EF >50%). There was a good linear correlation between the S/D ratio and the a´ velocity, but a tendency towards a negative correlation between the S/D ratio and the e´ velocity. S/D ratio <1 was seen in 43 patients. These patients had a significantly lower a´ velocity compared to those with S/D-ratio ≥1, septal (6,1 ± 2,4 v 8,8 ± 2,1 cm/s; p < .001) and lateral (6,0 ± 2,6 v 9,3 ± 2,5 cm/s; p < .001) No significant difference was seen in the septal e´ velocity (6,8 ± 2,4 v 6,8 ± 2,1 cm/s), lateral e´ velocity (9,4 ± 2,6 v 9,1 ± 2,8 cm/s) or in the ejection fraction (58,6 ± 4,4% v 58,7 ± 4,0%). A diastolic dysfunction was present in 62 patients, normal diastolic function in 231 patients. The a´ velocity was significantly lower in patients with S/D ratio <1 in both groups (p < .01). The a´ velocity is superior to the e´ velocity in predicting S/D ratio <1 in patients with normal ejection fraction regardless the ASE/EACVI diastolic classification. A failing left atrium seems to be the explanation.

Stearoyl-CoA desaturase indexes and n-6/n-3 fatty acids ratio as biomarkers of cardiometabolic risk factors in normal-weight rabbits fed high fat diets.

PubMed

Alarcón, Gabriela; Roco, Julieta; Medina, Analia; Van Nieuwenhove, Carina; Medina, Mirta; Jerez, Susana

2016-01-20

Biomarkers for cardiometabolic risk (CMR) factors would be important tools to maximize the effectiveness of dietary interventions to prevent cardiovascular diseases. Thus, the aim of this work was to analyze stearoyl-CoA desaturase (SCD) indexes and n-6/n-3 fatty acids (FA) ratio as biomarkers of CMR induced by feeding rabbits on high fat diets (HFDs). Rabbits were fed either regular diet or 18 % fat in regular diet (HFD) or 1 % cholesterol diet (HD) or diet containing 1 % cholesterol and 18 % fat (HFD-HD) during 6 weeks. Body weights (BW), blood pressure, visceral abdominal fat (VAF) and glucose tolerance test were determined. Total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), triglycerides (TG), fasting glucose (FG), and FA levels from plasma were measured. SCD indexes were calculated as product/precursor ratios of individual FA. BW was similar in all diet groups. HD increased TC, LDL-C, HDL-C, and TG. HFD increased TG, VAF and FG, and decreased HDL-C. The addition of HFD to HD joined to dyslipidemia increased VAF and FG. SCD indexes were increased and n-6/n-3 was unchanged in HD. SCD indexes were reduced and n-6/n-3 FA ratio was increased in HFD and HFD-HD. CMR factors were correlated positively with n-6/n-3 FA ratio. Although VAF had a stronger correlation with n-6/n-3 FA ratio than with SCD indexes, VAF was associated independently to both markers. HFD simulating lipid composition of the average Western-style diet induced experimental rabbit models of normal-weight metabolic syndrome (MS). SCD indexes and n-6/n-3 were modified according to the type of dietary fat. Considering that VAF and CMR factors appear to be stronger associated to n-6/n-3 FA ratio than to SCD indexes, n-6/n-3 FA ratio may be a better biomarker of MS and CMR in normal-weight subjects than SCD indexes.

Structure of the Dominant Negative S17N Mutant of Ras

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nassar, N.; Singh, K; Garcia-Diaz, M

2010-01-01

The use of the dominant negative mutant of Ras has been crucial in elucidating the cellular signaling of Ras in response to the activation of various membrane-bound receptors. Although several point mutants of Ras exhibit a dominant negative effect, the asparagine to serine mutation at position 17 (S17N) remains the most popular and the most effective at inhibiting the activation of endogenous Ras. It is now widely accepted that the dominant negative effect is due to the ability of the mutant to sequester upstream activators and its inability to activate downstream effectors. Here, we present the crystal structure of RasS17Nmore » in the GDP-bound form. In the three molecules that populate the asymmetric unit, the Mg{sup 2+} ion that normally coordinates the {beta}-phosphate is absent because of steric hindrance from the Asn17 side chain. Instead, a Ca{sup 2+} ion is coordinating the {alpha}-phosphate. Also absent from one molecule is electron density for Phe28, a conserved residue that normally stabilizes the nucleotide's guanine base. Except for Phe28, the nucleotide makes conserved interactions with Ras. Combined, the inability of Phe28 to stabilize the guanine base and the absence of a Mg{sup 2+} ion to neutralize the negative charges on the phosphates explain the weaker affinity of GDP for Ras. Our data suggest that the absence of the Mg{sup 2+} should also dramatically affect GTP binding to Ras and the proper positioning of Thr35 necessary for the activation of switch 1 and the binding to downstream effectors, a prerequisite for the triggering of signaling pathways.« less

46 CFR 401.428 - Basic rates and charges for carrying a U.S. pilot beyond normal change point or for boarding at...

Code of Federal Regulations, 2010 CFR

2010-10-01

... boarding point, the ship shall pay at the rate of $719 per day or part thereof, plus reasonable travel... normal change point or for boarding at other than the normal boarding point. 401.428 Section 401.428... carrying a U.S. pilot beyond normal change point or for boarding at other than the normal boarding point...

Trends over 5 decades in U.S. occupation-related physical activity and their associations with obesity.

PubMed

Church, Timothy S; Thomas, Diana M; Tudor-Locke, Catrine; Katzmarzyk, Peter T; Earnest, Conrad P; Rodarte, Ruben Q; Martin, Corby K; Blair, Steven N; Bouchard, Claude

2011-01-01

The true causes of the obesity epidemic are not well understood and there are few longitudinal population-based data published examining this issue. The objective of this analysis was to examine trends in occupational physical activity during the past 5 decades and explore how these trends relate to concurrent changes in body weight in the U.S. Analysis of energy expenditure for occupations in U.S. private industry since 1960 using data from the U.S. Bureau of Labor Statistics. Mean body weight was derived from the U.S. National Health and Nutrition Examination Surveys (NHANES). In the early 1960's almost half the jobs in private industry in the U.S. required at least moderate intensity physical activity whereas now less than 20% demand this level of energy expenditure. Since 1960 the estimated mean daily energy expenditure due to work related physical activity has dropped by more than 100 calories in both women and men. Energy balance model predicted weights based on change in occupation-related daily energy expenditure since 1960 for each NHANES examination period closely matched the actual change in weight for 40-50 year old men and women. For example from 1960-62 to 2003-06 we estimated that the occupation-related daily energy expenditure decreased by 142 calories in men. Given a baseline weight of 76.9 kg in 1960-02, we estimated that a 142 calories reduction would result in an increase in mean weight to 89.7 kg, which closely matched the mean NHANES weight of 91.8 kg in 2003-06. The results were similar for women. Over the last 50 years in the U.S. we estimate that daily occupation-related energy expenditure has decreased by more than 100 calories, and this reduction in energy expenditure accounts for a significant portion of the increase in mean U.S. body weights for women and men.

Trends over 5 Decades in U.S. Occupation-Related Physical Activity and Their Associations with Obesity

PubMed Central

Church, Timothy S.; Thomas, Diana M.; Tudor-Locke, Catrine; Katzmarzyk, Peter T.; Earnest, Conrad P.; Rodarte, Ruben Q.; Martin, Corby K.; Blair, Steven N.; Bouchard, Claude

2011-01-01

Background The true causes of the obesity epidemic are not well understood and there are few longitudinal population-based data published examining this issue. The objective of this analysis was to examine trends in occupational physical activity during the past 5 decades and explore how these trends relate to concurrent changes in body weight in the U.S. Methodology/Principal Findings Analysis of energy expenditure for occupations in U.S. private industry since 1960 using data from the U.S. Bureau of Labor Statistics. Mean body weight was derived from the U.S. National Health and Nutrition Examination Surveys (NHANES). In the early 1960's almost half the jobs in private industry in the U.S. required at least moderate intensity physical activity whereas now less than 20% demand this level of energy expenditure. Since 1960 the estimated mean daily energy expenditure due to work related physical activity has dropped by more than 100 calories in both women and men. Energy balance model predicted weights based on change in occupation-related daily energy expenditure since 1960 for each NHANES examination period closely matched the actual change in weight for 40–50 year old men and women. For example from 1960–62 to 2003–06 we estimated that the occupation-related daily energy expenditure decreased by 142 calories in men. Given a baseline weight of 76.9 kg in 1960–02, we estimated that a 142 calories reduction would result in an increase in mean weight to 89.7 kg, which closely matched the mean NHANES weight of 91.8 kg in 2003–06. The results were similar for women. Conclusion Over the last 50 years in the U.S. we estimate that daily occupation-related energy expenditure has decreased by more than 100 calories, and this reduction in energy expenditure accounts for a significant portion of the increase in mean U.S. body weights for women and men. PMID:21647427

FDG and Amyloid PET in Cognitively Normal Individuals at Risk for Late-Onset Alzheimer’s Disease

PubMed Central

Murray, John; Tsui, Wai H.; Li, Yi; McHugh, Pauline; Williams, Schantel; Cummings, Megan; Pirraglia, Elizabeth; Solnes, Lilja; Osorio, Ricardo; Glodzik, Lidia; Vallabhajosula, Shankar; Drzezga, Alexander; Minoshima, Satoshi; de Leon, Mony J.; Mosconi, Lisa

2014-01-01

Having a parent affected by late-onset Alzheimer’s disease (AD) is a major risk factor for cognitively normal (NL) individuals. This study explores the potential of PET with 18F-FDG and the amyloid- β (Aβ) tracer 11C-Pittsburgh Compound B (PiB) for detection of individual risk in NL adults with AD-parents. Methods FDG− and PiB-PET was performed in 119 young to late-middle aged NL individuals including 80 NL with positive family history of AD (FH+) and 39 NL with negative family history of any dementia (FH−). The FH+ group included 50 subjects with maternal (FHm) and 30 with paternal family history (FHp). Individual FDG and PiB scans were Z scored on a voxel-wise basis relative to modality-specific reference databases using automated procedures and rated as positive or negative (+/−) for AD-typical abnormalities using predefined criteria. To determine the effect of age, the cohort was separated into younger (49 ± 9 y) and older (68 ± 5 y) groups relative to the median age (60 y). Results Among individuals of age >60 y, as compared to controls, NL FH+ showed a higher frequency of FDG+ scans vs. FH− (53% vs. 6% p < 0.003), and a trend for PiB+ scans (27% vs. 11%; p = 0.19). This effect was observed for both FHm and FHp groups. Among individuals of age ≤60 y, NL FHm showed a higher frequency of FDG+ scans (29%) compared to FH− (5%, p = 0.04) and a trend compared to FHp (11%) (p = 0.07), while the distribution of PiB+ scans was not different between groups. In both age cohorts, FDG+ scans were more frequent than PiB+ scans among NL FH+, especially FHm (p < 0.03). FDG-PET was a significant predictor of FH+ status. Classification according to PiB status was significantly less successful. Conclusions Automated analysis of FDG− and PiB-PET demonstrates higher rates of abnormalities in at-risk FH+ vs FH− subjects, indicating potentially ongoing early AD-pathology in this population. The frequency of metabolic abnormalities was higher than that of A�

Trends in Ph.D. Productivity and Diversity in Top-50 U.S. Chemistry Departments: An Institutional Analysis

ERIC Educational Resources Information Center

Laursen, Sandra L.; Weston, Timothy J.

2014-01-01

The education of doctoral chemists contributes to the chemical research enterprise and thus to innovation as an engine of the economy. This quantitative analysis describes trends in the production and diversity of chemistry Ph.D. degrees in the top-50 U.S. Ph.D.-granting departments in the past two decades. Time series data for individual…

Hypermethylation of the Human Glutathione S-Transferase-π Gene (GSTP1) CpG Island Is Present in a Subset of Proliferative Inflammatory Atrophy Lesions but Not in Normal or Hyperplastic Epithelium of the Prostate

PubMed Central

Nakayama, Masashi; Bennett, Christina J.; Hicks, Jessica L.; Epstein, Jonathan I.; Platz, Elizabeth A.; Nelson, William G.; De Marzo, Angelo M.

2003-01-01

Somatic inactivation of the glutathione S-transferase-π gene (GSTP1) via CpG island hypermethylation occurs early during prostate carcinogenesis, present in ∼70% of high-grade prostatic intraepithelial neoplasia (high-grade PIN) lesions and more than 90% of adenocarcinomas. Recently, there has been a resurgence of the concept that foci of prostatic atrophy (referred to as proliferative inflammatory atrophy or PIA) may be precursor lesions for the development of prostate cancer and/or high-grade PIN. Many of the cells within PIA lesions contain elevated levels of GSTP1, glutathione S-transferase-α (GSTA1), and cyclooxygenase-II proteins, suggesting a stress response. Because not all PIA cells are positive for GSTP1 protein, we hypothesized that some of the cells within these regions acquire GSTP1 CpG island hypermethylation, increasing the chance of progression to high-grade PIN and/or adenocarcinoma. Separate regions (n =199) from 27 formalin-fixed paraffin-embedded prostates were microdissected by laser-capture microdissection (Arcturus PixCell II). These regions included normal epithelium (n = 48), hyperplasticepithelium from benign prostatic hyperplasia nodules (n = 22), PIA (n = 64), high-grade PIN (n = 32), and adenocarcinoma (n = 33). Genomic DNA was isolated and assessed for GSTP1 CpG island hypermethylation by methylation-specific polymerase chain reaction. GSTP1 CpG island hypermethylation was not detected in normal epithelium (0 of 48) or in hyperplastic epithelium (0 of 22), but was found in 4 of 64 (6.3%) PIA lesions. The difference in the frequency of GSTP1 CpG island hypermethylation between normal or hyperplastic epithelium and PIA was statistically significant (P = 0.049). Similar to studies using nonmicrodissected cases, hypermethylation was found in 22 of 32 (68.8%) high-grade PIN lesions and in 30 of 33 (90.9%) adenocarcinoma lesions. Unlike normal or hyperplastic epithelium, GSTP1 CpG island hypermethylation can be detected in some PIA

Trends of ozone total columns and vertical distribution from FTIR observations at 8 NDACC stations around the globe

NASA Astrophysics Data System (ADS)

Vigouroux, C.; Blumenstock, T.; Coffey, M.; Errera, Q.; García, O.; Jones, N. B.; Hannigan, J. W.; Hase, F.; Liley, B.; Mahieu, E.; Mellqvist, J.; Notholt, J.; Palm, M.; Persson, G.; Schneider, M.; Servais, C.; Smale, D.; Thölix, L.; De Mazière, M.

2014-09-01

Ground-based Fourier transform infrared (FTIR) measurements of solar absorption spectra can provide ozone total columns with a precision of 2%, but also independent partial column amounts in about four vertical layers, one in the troposphere and three in the stratosphere up to about 45 km, with a precision of 5-6%. We use eight of the Network for the Detection of Atmospheric Compososition Change (NDACC) stations having a long-term time series of FTIR ozone measurements to study the total and vertical ozone trends and variability, namely: Ny-Alesund (79° N), Thule (77° N), Kiruna (68° N), Harestua (60° N), Jungfraujoch (47° N), Izaña (28° N), Wollongong (34° S) and Lauder (45° S). The length of the FTIR time-series varies by station, but is typically from about 1995 to present. We applied to the monthly means of the ozone total and four partial columns a stepwise multiple regression model including the following proxies: solar cycle, Quasi-Biennial Oscillation (QBO), El Niño-Southern Oscillation (ENSO), Arctic and Antarctic Oscillation (AO/AAO), tropopause pressure (TP), equivalent latitude (EL), Eliassen-Palm flux (EPF), and volume of polar stratospheric clouds (VPSC). At the Arctic stations, the trends are found mostly negative in the troposphere and lower stratosphere, very mixed in the middle stratosphere, positive in the upper stratosphere due to a large increase in the 1995-2003 period, and non-significant when considering the total columns. The trends for mid-latitude and subtropical stations are all non-significant, except at Lauder in the troposphere and upper stratosphere, and at Wollongong for the total columns and the lower and middle stratospheric columns; at Jungfraujoch, the upper stratospheric trend is close to significance (+0.9 ± 1.0 % decade-1). Therefore, some signs of the onset of ozone mid-latitude recovery are observed only in the Southern Hemisphere, while a few more years seems to be needed to observe it at the northern mid

Trends of ozone total columns and vertical distribution from FTIR observations at eight NDACC stations around the globe

NASA Astrophysics Data System (ADS)

Vigouroux, C.; Blumenstock, T.; Coffey, M.; Errera, Q.; García, O.; Jones, N. B.; Hannigan, J. W.; Hase, F.; Liley, B.; Mahieu, E.; Mellqvist, J.; Notholt, J.; Palm, M.; Persson, G.; Schneider, M.; Servais, C.; Smale, D.; Thölix, L.; De Mazière, M.

2015-03-01

Ground-based Fourier transform infrared (FTIR) measurements of solar absorption spectra can provide ozone total columns with a precision of 2% but also independent partial column amounts in about four vertical layers, one in the troposphere and three in the stratosphere up to about 45km, with a precision of 5-6%. We use eight of the Network for the Detection of Atmospheric Composition Change (NDACC) stations having a long-term time series of FTIR ozone measurements to study the total and vertical ozone trends and variability, namely, Ny-Ålesund (79° N), Thule (77° N), Kiruna (68° N), Harestua (60° N), Jungfraujoch (47° N), Izaña (28° N), Wollongong (34° S) and Lauder (45° S). The length of the FTIR time series varies by station but is typically from about 1995 to present. We applied to the monthly means of the ozone total and four partial columns a stepwise multiple regression model including the following proxies: solar cycle, quasi-biennial oscillation (QBO), El Niño-Southern Oscillation (ENSO), Arctic and Antarctic Oscillation (AO/AAO), tropopause pressure (TP), equivalent latitude (EL), Eliassen-Palm flux (EPF), and volume of polar stratospheric clouds (VPSC). At the Arctic stations, the trends are found mostly negative in the troposphere and lower stratosphere, very mixed in the middle stratosphere, positive in the upper stratosphere due to a large increase in the 1995-2003 period, and non-significant when considering the total columns. The trends for mid-latitude and subtropical stations are all non-significant, except at Lauder in the troposphere and upper stratosphere and at Wollongong for the total columns and the lower and middle stratospheric columns where they are found positive. At Jungfraujoch, the upper stratospheric trend is close to significance (+0.9 ± 1.0% decade-1). Therefore, some signs of the onset of ozone mid-latitude recovery are observed only in the Southern Hemisphere, while a few more years seem to be needed to observe it at

Youth Suicide Trends in Finland, 1969-2008

ERIC Educational Resources Information Center

Lahti, Anniina; Rasanen, Pirkko; Riala, Kaisa; Keranen, Sirpa; Hakko, Helina

2011-01-01

Background: There are only a few recent studies on secular trends in child and adolescent suicides. We examine here trends in rates and methods of suicide among young people in Finland, where suicide rates at these ages are among the highest in the world. Methods: The data, obtained from Statistics Finland, consisted of all suicides (n = 901)…

Normal-range verbal-declarative memory in schizophrenia.

PubMed

Heinrichs, R Walter; Parlar, Melissa; Pinnock, Farena

2017-10-01

Cognitive impairment is prevalent and related to functional outcome in schizophrenia, but a significant minority of the patient population overlaps with healthy controls on many performance measures, including declarative-verbal-memory tasks. In this study, we assessed the validity, clinical, and functional implications of normal-range (NR), verbal-declarative memory in schizophrenia. Performance normality was defined using normative data for 8 basic California Verbal Learning Test (CVLT-II; Delis, Kramer, Kaplan, & Ober, 2000) recall and recognition trials. Schizophrenia patients (n = 155) and healthy control participants (n = 74) were assessed for performance normality, defined as scores within 1 SD of the normative mean on all 8 trials, and assigned to normal- and below-NR memory groups. NR schizophrenia patients (n = 26) and control participants (n = 51) did not differ in general verbal ability, on a reading-based estimate of premorbid ability, across all 8 CVLT-II-score comparisons or in terms of intrusion and false-positive errors and auditory working memory. NR memory patients did not differ from memory-impaired patients (n = 129) in symptom severity, and both patient groups were significantly and similarly disabled in terms of functional status in the community. These results confirm a subpopulation of schizophrenia patients with normal, verbal-declarative-memory performance and no evidence of decline from higher premorbid ability levels. However, NR patients did not experience less severe psychopathology, nor did they show advantage in community adjustment relative to impaired patients. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Sequencing and annotation of the chloroplast DNAs and identification of polymorphisms distinguishing normal male-fertile and male-sterile cytoplasms of onion

USDA-ARS?s Scientific Manuscript database

Due the biennial generation time of onion, classical crossing takes at least four years to classify cytoplasms as normal (N) male-fertile or male-sterile (S). Molecular markers in the organellar DNAs that distinguish N and S cytoplasms are useful to reduce the time required to classify onion cytopla...

Prevalence and trends of leisure-time physical activity by occupation and industry in U.S. workers: the National Health Interview Survey 2004-2014.

PubMed

Gu, Ja K; Charles, Luenda E; Ma, Claudia C; Andrew, Michael E; Fekedulegn, Desta; Hartley, Tara A; Violanti, John M; Burchfiel, Cecil M

2016-10-01

Studies describing prevalence and trends of physical activity among workers in the United States are scarce. We aimed to estimate prevalence and trends of "sufficient" leisure-time physical activity (LTPA) during the 2004-2014 time period among U.S. workers. Data were collected for U.S. workers in the National Health Interview Survey. LTPA was categorized as sufficiently active (moderate intensity, ≥150 minutes per week), insufficiently active (10-149 minutes per week), and inactive (<10 minutes per week). Prevalence of LTPA was adjusted for age using 2010 U.S. working population as a standardized age distribution. Prevalence trends of "sufficient" LTPA significantly increased from 2004 to 2014 (45.6% to 54.8%; P < .001). Among industry groups, the highest prevalence of "sufficient" LTPA was observed among workers in Professional/Scientific/Technical Services (62.1%). The largest increases were observed among workers in Public Administration (51.3%-63.4%). Among occupational groups, "sufficient" LTPA prevalence was lowest in farming/fishing/forestry (30.8%) and highest in life/physical/social science (66.4%). Prevalence of LTPA significantly increased from 2004 to 2014 in most occupational and industry groups. Among U.S. workers, trends of "sufficient" LTPA significantly increased between 2004 and 2014. Overall, a larger proportion of white-collar compared to blue-collar workers were engaged in "sufficient" LTPA. Published by Elsevier Inc.

A project for monitoring trends in burn severity

USGS Publications Warehouse

Eidenshink, Jeffery C.; Schwind, Brian; Brewer, Ken; Zhu, Zhu-Liang; Quayle, Brad; Howard, Stephen M.

2007-01-01

Jeff Eidenshink, Brian Schwind, Ken Brewer, Zhi-Liang Zhu, Brad Quayle, and Elected officials and leaders of environmental agencies need information about the effects of large wildfires in order to set policy and make management decisions. Recently, the Wildland Fire Leadership Council (WFLC), which implements and coordinates the National Fire Plan (NFP) and Federal Wildland Fire Management Policies (National Fire Plan 2004), adopted a strategy to monitor the effectiveness of the National Fire Plan and the Healthy Forests Restoration Act (HFRA). One component of this strategy is to assess the environmental impacts of large wildland fires and identify the trends of burn severity on all lands across the United States. To that end, WFLC has sponsored a six-year project, Monitoring Trends in Burn Severity (MTBS), which requires the U.S. Department of Agriculture Forest Service (USDA-FS) and the U.S. Geological Survey (USGS) to map and assess the burn severity for all large current and historical fires. Using Landsat data and the differenced Normalized Burn Ratio (dNBR) algorithm, the USGS Center for Earth Resources Observation and Science (EROS) and USDA-FS Remote Sensing Applications Center will map burn severity of all fires since 1984 greater than 202 ha (500ac) in the east, and 404 ha (1,000 ac) in the west. The number of historical fires from this period combined with current fires occurring during the course of the project will exceed 9,000. The MTBS project will generate burn severity data, maps, and reports, which will be available for use at local, state, and national levels to evaluate trends in burn severity and help develop and assess the effectiveness of land management decisions. Additionally, the information developed will provide a baseline from which to monitor the recovery and health of fire-affected landscapes over time. Spatial and tabular data quantifying burn severity will augment existing information used to estimate risk associated with a range

Breaking Through the Multi-Mesa-Channel Width Limited of Normally Off GaN HEMTs Through Modulation of the Via-Hole-Length.

PubMed

Chien, Cheng-Yen; Wu, Wen-Hsin; You, Yao-Hong; Lin, Jun-Huei; Lee, Chia-Yu; Hsu, Wen-Ching; Kuan, Chieh-Hsiung; Lin, Ray-Ming

2017-12-01

We present new normally off GaN high-electron-mobility transistors (HEMTs) that overcome the typical limitations in multi-mesa-channel (MMC) width through modulation of the via-hole-length to regulate the charge neutrality screen effect. We have prepared enhancement-mode (E-mode) GaN HEMTs having widths of up to 300 nm, based on an enhanced surface pinning effect. E-mode GaN HEMTs having MMC structures and widths as well as via-hole-lengths of 100 nm/2 μm and 300 nm/6 μm, respectively, exhibited positive threshold voltages (V th ) of 0.79 and 0.46 V, respectively. The on-resistances of the MMC and via-hole-length structures were lower than those of typical tri-gate nanoribbon GaN HEMTs. In addition, the devices not only achieved the E-mode but also improved the power performance of the GaN HEMTs and effectively mitigated the device thermal effect. We controlled the via-hole-length sidewall surface pinning effect to obtain the E-mode GaN HEMTs. Our findings suggest that via-hole-length normally off GaN HEMTs have great potential for use in next-generation power electronics.

AIRS Water Vapor and Cloud Products Validate and Explain Recent Negative Global and Tropical OLR Trends Observed by CERES

NASA Astrophysics Data System (ADS)

Susskind, J.; Molnar, G. I.; Iredell, L. F.; Sounder Research Team

2010-12-01

Joel Susskind, Gyula Molnar, and Lena Iredell NASA GSFC Sounder Research Team Abstract This paper compares spatial and temporal anomalies and trends of OLR as observed by CERES and computed based on AIRS retrieved surface and atmospheric geophysical parameters over the time period September 2002 - February 2010. This time period is marked by a substantial decreasing OLR trend on the order of -0.1 W/m2/yr averaged over the globe. There are very large spatial variations of these trends however, with local values ranging from -2.6 W/m2/yr to +3.0 W/m2/yr in the tropics. The spatial patterns of the AIRS and CERES trends are in essentially perfect agreement with each other, as are the anomaly time series averaged over different spatial regions. This essentially perfect agreement of OLR anomalies and trends derived from observations by two different instruments, in totally independent and different manners, implies that both sets of results must be highly accurate. The agreement of anomalies and trends of OLR as observed by CERES and computed from AIRS derived products also indirectly validates the anomalies and trends of the AIRS derived products as well. We used the anomalies and trends of AIRS derived water vapor and cloud products to explain why global OLR has had a large negative trend over the time period September 2002 through February 2010. Tropical OLR began to decrease significantly at the onset of a strong La Niña in mid-2007. AIRS products show that cloudiness and mid-tropospheric water vapor began to increase in the region 5°N - 20°S latitude extending eastward from 150°W - 30°E longitude at that time, with a corresponding very large drop in OLR in this region. Late 2009 is characterized by a strong El-Niño, with a corresponding change in sign of observed anomalies of mid-tropospheric water vapor, cloud cover, and OLR in this region, as well as that of OLR anomalies in the tropics and globally. Monthly mean anomalies of OLR, water vapor and cloud cover

Trends in Research with U.S. Military Service Member Participants: A Population-Specific ClinicalTrials.gov Review.

PubMed

Cook, Wendy A; Doorenbos, Ardith Z; Bridges, Elizabeth J

2016-08-15

ClinicalTrials.gov reviews have evaluated research trends for specific conditions and age groups but not for specific populations of research participants. No ClinicalTrials.gov reviews have evaluated research with military service member participants. Study objectives were (a) to use ClinicalTrials.gov to identify trends in biomedical research from 2005 to 2014 in which U.S. military service members actively participated as research participants and (b) to describe a search strategy for adaptation in future ClinicalTrials.gov reviews of specific participant populations. A systematic review of ClinicalTrials.gov was performed to identify studies that included U.S. service members as participants, either exclusively or with other groups of participants. U.S. service members were identified as participants in 512 studies. Service members participated together with other groups in 392 studies, while 120 studies included only service members. The top five conditions of interest were post-traumatic stress disorder, traumatic brain injury, amputations, burns, and ocular injuries/disorders. The number of studies started each year peaked in 2011 and declined from 2012 to 2014. Twenty-five percent of studies exclusive to service members aimed to enroll 500 or more participants. Research exclusive to Guard and Reserve service members during this period was limited. U.S. military service members participate in biomedical research. To address the health needs of U.S. service members, it is important to ensure there is not a prolonged decline in research among this population. The search strategy may be adapted to ClinicalTrials.gov reviews of specific participant populations for which straightforward searches are not possible.

Passage from normal mucosa to adenoma and colon cancer: alteration of normal sCD30 mechanisms regulating TH1/TH2 cell functions.

PubMed

Contasta, Ida; Berghella, Anna Maria; Pellegrini, Patrizia; Adorno, Domenico

2003-08-01

The pathogenesis of cancer is currently under intensive investigation to identify reliable prognostic indices for the early detection of disease. Adenomas have been identified as precursors of colorectal cancer and tumor establishment, and disease progression has been found to reflect a malfunction of the immune system. On the basis of the role of the CD30 molecule in the regulation of TH1/TH2 functions and our previous results, strongly suggesting the validity of serum TH1/TH2 cytokines in the study of tumor progression, we studied network interaction between the production of soluble (s) CD30/sBCl2 in whole blood culture [in basic conditions and after PHA, LPS, and anti-CD3 monoclonal antibody (mAb) stimulation] and levels of TH1/TH2 cytokines (IL2, IFN gamma, IL12, IL4, IL5, IL10). Peripheral blood from a group of healthy subjects, as well as from patients with adenoma and colorectal cancer was used. Our objective was to gain a better insight into the role of the CD30 molecule in the passage from normal mucosa to adenoma and tumor and identify specific disease markers. Our results suggest that the decrease in CD30 expression and the abnormal increase in Bcl2 expression, observed in the peripheral cells of both adenoma and tumor groups determine an imbalance between TH1/TH2 functions. Consequently, changes in sCD30/sBcl2 culture production and TH1/TH2 cytokine serum levels may be reliable markers for tumor progression. In fact, our overall data show that a decrease of sCD30 levels in basic and PHA conditions and an increase of IFN gamma, IL4, IL5, and IL12 serum levels and sBcl2 in all activation condition are indicative of the passage from normal mucosa to adenoma; whilst a decrease of sBcl2 level in basic, LPS and anti-CD3 conditions and of IL2, IFN gamma serum levels, together with an increase of IL5 are indicative of the passage from adenoma to tumor.

Trend analysis of the homogenized total ozone series of Arosa (Switzerland), 1926-1996

NASA Astrophysics Data System (ADS)

Staehelin, Johannes; Kegel, Rainer; Harris, Neil R. P.

1998-04-01

Total ozone measurements have been made at Arosa, Switzerland (47°N), from 1926 through the present day, forming the longest total ozone series in the world. The record has been recently homogenized. Ozone trends are calculated to be -(2.3±0.6)% per decade for annual means (larger losses are found in winter and spring, approximately -4% per decade for trends in January, February, and March) when a simple linear change from 1970 to 1996 is assumed. In addition, total ozone trends are calculated using multiple regression models involving combinations of explanatory variables for the 11-year solar cycle, local meteorological conditions (the Mount Säntis high-altitude temperature record), stratospheric aerosol loading from volcanoes, and stratospheric chlorine loading. When the terms for the solar cycle, the stratospheric aerosol loading and the high mountain temperature record were included, the annually averaged ozone trends were found to be -(1.9±0.6)% per decade. While a statistically significant relation is found between total ozone and indices of aerosol loadings of the stratosphere, the recent decrease in total ozone cannot be accounted for by the higher average aerosol content in the second half of the century. Finally, the decrease in ozone in the stratosphere is estimated to be approximately 30% larger than that found for total ozone, when a crude estimate of the increase in tropospheric ozone is included. The acceleration observed in total ozone trends between the 1970s and the 1980s over northern midlatitudes [e.g., Harris et al., 1997] might be partially attributed to the larger increase in tropospheric ozone in the 1970s.

An Intercomparison of the Deposition Models Used in the CASTNET and CAPMoN Networks

EPA Science Inventory

To assess long-term trends in atmospheric deposition, the U.S. operates the Clean Air Status and Trends Network (CASTNET) and Canada operates the Canadian Air and Precipitation Monitoring Network (CAPMoN). Both networks use modeled dry deposition velocities and measured atmospher...

Statistical analysis of strait time index and a simple model for trend and trend reversal

NASA Astrophysics Data System (ADS)

Chen, Kan; Jayaprakash, C.

2003-06-01

We analyze the daily closing prices of the Strait Time Index (STI) as well as the individual stocks traded in Singapore's stock market from 1988 to 2001. We find that the Hurst exponent is approximately 0.6 for both the STI and individual stocks, while the normal correlation functions show the random walk exponent of 0.5. We also investigate the conditional average of the price change in an interval of length T given the price change in the previous interval. We find strong correlations for price changes larger than a threshold value proportional to T; this indicates that there is no uniform crossover to Gaussian behavior. A simple model based on short-time trend and trend reversal is constructed. We show that the model exhibits statistical properties and market swings similar to those of the real market.

Trends in urodynamics in U.S. female medicare beneficiaries, 2000-2010.

PubMed

Reynolds, W Stuart; Ni, Shenghua; Kaufman, Melissa R; Penson, David F; Dmochowski, Roger R

2015-06-01

To document variations and temporal trends in the use of urodynamics (UDS) in female U.S. Medicare beneficiaries. Using a 5% sample of U.S. Medicare utilization records, we identified female beneficiaries who had undergone UDS studies between 2000 and 2010 by the presence of Common Procedural Terminology codes for cystometrogram in claims from the Carrier file. We abstracted data for each patient on age, race, residence, ICD9 diagnoses, dates of service, and provider specialty. We calculated rates per 100,000 beneficiaries with data available from the enrollment files (i.e., Denominator files) and reported the numbers and rates per 100,000 by year. During this period, 1.4 million female U.S. Medicare beneficiaries underwent UDS, of which 6% were videourodynamics. Seventy four percent of UDS were associated with a diagnosis of any urinary incontinence, with 50% specific for stress incontinence. The annual rates of UDS increased by 29%, from 422 in 2000 to 543 in 2010 per 100,000. Similar increases were seen across age groups, geographic regions and racial/ethnic groups. The rate of UDS performed by gynecologists increased by 144% over the study period, while that of urologists decreased by 3%. In 2010, gynecologists performed 35% and urologists 58% of all UDS. The use of UDS in the female Medicare program increased substantially between 2000 and 2010, with some variation across demographics and marked variation across provider specialty. © 2014 Wiley Periodicals, Inc.

[(S)-1-Carbamoylethyl]bis(dimethylglyoximato-kappa2N,N')[(S)-1-phenylethylamine]cobalt(III) and bis(dimethylglyoximato-kappa2N,N')[(R)-1-(N-methylcarbamoyl)ethyl][(R)-1-phenylethylamine]cobalt(III) monohydrate.

PubMed

Orisaku, Keiko Komori; Hagiwara, Mieko; Ohgo, Yoshiki; Arai, Yoshifusa; Ohgo, Yoshiaki

2005-04-01

The title complexes, [Co(C3H6NO)(C4H7N2O2)2(C8H11N)] and [Co(C4H8NO)(C4H7N2O2)2(C8H11N)].H2O, were resolved from [(RS)-1-carbamoylethyl]bis(dimethylglyoximato)[(S)-1-phenylethylamine]cobalt(III) and bis(dimethylglyoximato)[(RS)-1-(N-methylcarbamoyl)ethyl][(R)-1-phenylethylamine]cobalt(III), respectively, and their crystal structures were determined in order to reveal the absolute configuration of the major enantiomer produced in the photoisomerization of each series of 2-carbamoylethyl and 2-(N-methylcarbamoyl)ethyl cobaloxime complexes.

Circulating Sex Hormones and Terminal Duct Lobular Unit Involution of the Normal Breast

PubMed Central

Khodr, Zeina G.; Sherman, Mark E.; Pfeiffer, Ruth M.; Gierach, Gretchen L.; Brinton, Louise A.; Falk, Roni T.; Patel, Deesha A.; Linville, Laura M.; Papathomas, Daphne; Clare, Susan E.; Visscher, Daniel W.; Mies, Carolyn; Hewitt, Stephen M.; Storniolo, Anna Maria V.; Rosebrock, Adrian; Caban, Jesus J.; Figueroa, Jonine D.

2014-01-01

Background Terminal duct lobular units (TDLUs) are the predominant source of breast cancers. Lesser degrees of age-related TDLU involution have been associated with increased breast cancer risk, but factors that influence involution are largely unknown. We assessed whether circulating hormones, implicated in breast cancer risk, are associated with levels of TDLU involution using data from the Susan G. Komen Tissue Bank (KTB) at the Indiana University Simon Cancer Center (2009-2011). Methods We evaluated three highly reproducible measures of TDLU involution, using normal breast tissue samples from the KTB (n=390): TDLU counts, median TDLU span, and median acini counts per TDLU. Relative risks (RRs, for continuous measures), odds ratios (ORs, for categorical measures), 95% confidence intervals (CIs), and p-trends were calculated to assess the association between tertiles of estradiol, testosterone, sex hormone-binding globulin (SHBG), progesterone, and prolactin with TDLU measures. All models were stratified by menopausal status and adjusted for confounders. Results Among premenopausal women, higher prolactin levels were associated with higher TDLU counts (RRT3vsT1:1.18, 95% CI: 1.07-1.31; p-trend=0.0005), but higher progesterone was associated with lower TDLU counts (RRT3vsT1: 0.80, 95% CI: 0.72-0.89; p-trend<0.0001). Among postmenopausal women, higher levels of estradiol (RRT3vsT1:1.61, 95% CI: 1.32-1.97; p-trend<0.0001) and testosterone (RRT3vsT1: 1.32, 95% CI: 1.09-1.59; p-trend=0.0043) were associated with higher TDLU counts. Conclusions These data suggest that select hormones may influence breast cancer risk potentially through delaying TDLU involution. Impact Increased understanding of the relationship between circulating markers and TDLU involution may offer new insights into breast carcinogenesis. PMID:25472681

On signals faint and sparse: The ACICA algorithm for blind de-trending of exoplanetary transits with low signal-to-noise

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waldmann, I. P., E-mail: ingo@star.ucl.ac.uk

2014-01-01

Independent component analysis (ICA) has recently been shown to be a promising new path in data analysis and de-trending of exoplanetary time series signals. Such approaches do not require or assume any prior or auxiliary knowledge about the data or instrument in order to de-convolve the astrophysical light curve signal from instrument or stellar systematic noise. These methods are often known as 'blind-source separation' (BSS) algorithms. Unfortunately, all BSS methods suffer from an amplitude and sign ambiguity of their de-convolved components, which severely limits these methods in low signal-to-noise (S/N) observations where their scalings cannot be determined otherwise. Here wemore » present a novel approach to calibrate ICA using sparse wavelet calibrators. The Amplitude Calibrated Independent Component Analysis (ACICA) allows for the direct retrieval of the independent components' scalings and the robust de-trending of low S/N data. Such an approach gives us an unique and unprecedented insight in the underlying morphology of a data set, which makes this method a powerful tool for exoplanetary data de-trending and signal diagnostics.« less

Chondroitin Sulfate N-Acetylgalactosaminyltransferase 1 Is Necessary for Normal Endochondral Ossification and Aggrecan Metabolism*

PubMed Central

Sato, Takashi; Kudo, Takashi; Ikehara, Yuzuru; Ogawa, Hiroyasu; Hirano, Tomoko; Kiyohara, Katsue; Hagiwara, Kozue; Togayachi, Akira; Ema, Masatsugu; Takahashi, Satoru; Kimata, Koji; Watanabe, Hideto; Narimatsu, Hisashi

2011-01-01

Chondroitin sulfate (CS) is a glycosaminoglycan, consisting of repeating disaccharide units of N-acetylgalactosamine and glucuronic acid residues, and plays important roles in development and homeostasis of organs and tissues. Here, we generated and analyzed mice lacking chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGalNAcT-1). Csgalnact1−/− mice were viable and fertile but exhibited slight dwarfism. Biochemically, the level of CS in Csgalnact1−/− cartilage was reduced to ∼50% that of wild-type cartilage, whereas its chain length was similar to wild-type mice, indicating that CSGalNAcT-1 participates in the CS chain initiation as suggested in the previous study (Sakai, K., Kimata, K., Sato, T., Gotoh, M., Narimatsu, H., Shinomiya, K., and Watanabe, H. (2007) J. Biol. Chem. 282, 4152–4161). Histologically, the growth plate of Csgalnact1−/− mice contained shorter and slightly disorganized chondrocyte columns with a reduced volume of the extracellular matrix principally in the proliferative layer. Immunohistochemical analysis revealed that the level of both aggrecan and link protein 1 were decreased in Csgalnact1−/− cartilage. Western blot analysis demonstrated an increase in processed forms of aggrecan core protein. These results suggest that CSGalNAcT-1 is required for normal levels of CS biosynthesis in cartilage. Our observations suggest that CSGalNAcT-1 is necessary for normal levels of endochondral ossification, and the decrease in CS amount in the growth plate by its absence causes a rapid catabolism of aggrecan. PMID:21148564

Notes on S-folds and {N} = 3 theories

NASA Astrophysics Data System (ADS)

Agarwal, Prarit; Amariti, Antonio

2016-09-01

We consider D3 branes in presence of an S-fold plane. The latter is a non-perturbative object, arising from the combined projection of an S-duality twist and a discrete orbifold of the R-symmetry group. This construction naively gives rise to 4d {N} = 3 SCFTs. Nevertheless it has been observed that in some cases supersymmetry is enhanced to {N} = 4. In this paper we study the explicit counting of degrees of freedom arising from vector multiplets associated to strings suspended between the D3 branes probing the S-fold. We propose that, for trivial discrete torsion, there is no vector multiplet associated to (1, 0) strings stretched between a brane and its image. We then focus on the case of rank 2 {N} = 3 theory that enhances to SU(3) {N} = 4 SYM, explicitly spelling out the isomorphism between the BPS-spectrum of the manifestly {N} = 3 theory and that of three D3 branes in flat spacetime. Subsequently, we consider 3-pronged strings in these setups and show how wall-crossing in the S-fold background implies wall crossing in the flat geometry. This can be considered a consistency check of the conjectured SUSY enhancement. We also find that the above isomorphism implies that a (1, 0) string, suspended between a brane and its image in the S-fold, corresponds to a 3-string junction in the flat geometry. This is in agreement with our claim on the absence of a vector multiplet associated to such (1, 0) strings. This is because the 3-string junction in flat geometry gives rise to a 1/4-th BPS multiplet of the {N} = 4 algebra. Such multiplets always include particles with spin > 1 as opposed to a vector multiplet which is restricted by the requirement that the spins must be ≤ 1.

[The discrimination of mono-syllable words in noise in listeners with normal hearing].

PubMed

Yoshida, M; Sagara, T; Nagano, M; Korenaga, K; Makishima, K

1992-02-01

The discrimination of mono-syllable words (67S word-list) pronounced by a male and a female speaker was investigated in noise in 39 normal hearing subjects. The subjects listened to the test words at a constant level of 62 dB together with white or weighted noise in four S/N conditions. By processing the data with logit transformation, S/N-discrimination curves were presumed for each combination of a speech material and a noise. Regardless of the type of noise, the discrimination scores for the female voice started to decrease gradually at a S/N ratio of +10 dB, and reached 10 to 20% at-10 dB. For the male voice in white noise, the discrimination curve was similar to those for the female voice. On the contrary, the discrimination score for the male voice in weighted noise declined rapidly from a S/N ratio of +5 dB, and went below 10% at -5 dB. The discrimination curves seem to be shaped by the interrelations between the spectrum of the speech material and that of the noise.

Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Performance Verification Report, METSAT (S/N:107) AMSU-A1 Receiver Assemblies: P/N 1356429-1, S/N:F04, P/N 1356409-1,S/N F04

NASA Technical Reports Server (NTRS)

Pines, D.

1999-01-01

This is the Performance Verification Report, METSAT (S/N: 107) AMSU-A1 Receiver Assemblies, P/N 1356429-1, SIN: F04, P/N 1356409- 1, S/N: F04, for the Integrated Advanced Microwave Sounding Unit-A (AMSU-A). The AMSU-A receiver subsystem comprises two separated receiver assemblies; AMSU-A1 and AMSU-A2 (P/N 1356441-1). The AMSU-A1 receiver contains 13 channels and the AMSU-A2 receiver 2 channels. The AMSU-A receiver assembly is further divided into two parts; AMSU-A I - I (P/N 13 5 6429- 1) and AMSU-A 1 -2 (P/N 1356409-1), which contain 9 and 4 channels, respectively. The AMSU-A receiver subsystem is located in between the antenna and signal processing subsystems of the AMSU-A instrument and comprises the RF and IF components from isolators to attenuators. It receives the RF signals from the antenna subsystem, down-converts the RF signals to IF signals, amplifies and defines the IF signals to proper power level and frequency bandwidth as specified for each channel, and inputs the IF signals to the signal processing subsystem. The test reports for the METSAT AMSU-A receiver subsystem are prepared separately for Al and A2 receivers so that each receiver stands alone during integration of instruments into the spacecraft. This test report presents the test data of the N4ETSAT AMSU-A1 Flight Model No. 4 (FM-4) receiver subsystem. The tests are performed per the Acceptance Test Procedure (ATP) for the AMSU-A Receiver Subsystem, AE-26002/6A. The functional performance tests are conducted either at the component or subsystem level. While the component-level tests are performed over the entire operating temperature range predicted by thermal analysis, most subsystem-level tests are conducted at ambient temperature only. Key performances (bandpass characteristics and noise figure) of the receiver subsystem are verified over the operating temperature.

AdS/CFT beyond the N = 4 SYM paradigm

NASA Astrophysics Data System (ADS)

Pomoni, Elli

In this thesis we present studies in the AdS/CFT correspondence that intend to push the present knowledge beyond the N = 4 super Yang-Mills (SYM) paradigm. The first part is concerned with the study of non-supersymmetric deformations of N = 4 SYM (which still are in the N = 4 universality class). For non-supersymmetric CFT's at Large N we explore the correspondence between string theory tachyons in the bulk and instabilities on the boundary effective action. The operators dual to AdS tachyons have anomalous dimensions that are purely complex numbers. We give a prescription for calculating the mass of the tachyon from the field theory side. Moreover, we apply this general dictionary to the case of intersecting D7 flavor branes in AdS 5 x S5 and obtain the mass of the open string tachyon that is dual to the instability in the mesonic sector of the theory. In the second part we present work aiming at finding string theory duals for gauge theories beyond the N = 4 universality class, i.e. theories that have genuinely less supersymmetry and unquenched flavor. Arguably the next simplest example after N = 4 SYM is N = 2 SU(Nc) SYM coupled to Nf = 2Nc fundamental hypermultiplets. The theory admits a Veneziano expansion of large Nc and large Nf, with Nf/Nc and lambda = g2Nc kept fixed. The topological structure of large N diagrams invites a general conjecture: the flavor-singlet sector of a gauge theory in the Veneziano limit is dual to a closed string theory. We present the one-loop Hamiltonian for the scalar sector of N = 2 superconformal QCD and study this integrability of the theory. Furthermore, we explore the chiral spectrum of the protected operators of the theory using the one-loop anomalous dimensions and, additionally, by studying the index of the theory. We finally search for possible AdS dual trying to match the chiral spectrum. We conclude that the string dual is a sub-critical background containing both an AdS 5 and an S1 factor.

100 years of California’s water rights system: patterns, trends and uncertainty

NASA Astrophysics Data System (ADS)

Grantham, Theodore E.; Viers, Joshua H.

2014-08-01

For 100 years, California’s State Water Resources Control Board and its predecessors have been responsible for allocating available water supplies to beneficial uses, but inaccurate and incomplete accounting of water rights has made the state ill-equipped to satisfy growing societal demands for water supply reliability and healthy ecosystems. Here, we present the first comprehensive evaluation of appropriative water rights to identify where, and to what extent, water has been dedicated to human uses relative to natural supplies. The results show that water right allocations total 400 billion cubic meters, approximately five times the state’s mean annual runoff. In the state’s major river basins, water rights account for up to 1000% of natural surface water supplies, with the greatest degree of appropriation observed in tributaries to the Sacramento and San Joaquin Rivers and in coastal streams in southern California. Comparisons with water supplies and estimates of actual use indicate substantial uncertainty in how water rights are exercised. In arid regions such as California, over-allocation of surface water coupled with trends of decreasing supply suggest that new water demands will be met by re-allocation from existing uses. Without improvements to the water rights system, growing human and environmental demands portend an intensification of regional water scarcity and social conflict. California’s legal framework for managing its water resources is largely compatible with needed reforms, but additional public investment is required to enhance the capacity of the state’s water management institutions to effectively track and regulate water rights.

Trend analyses with river sediment rating curves

USGS Publications Warehouse

Warrick, Jonathan A.

2015-01-01

Sediment rating curves, which are fitted relationships between river discharge (Q) and suspended-sediment concentration (C), are commonly used to assess patterns and trends in river water quality. In many of these studies it is assumed that rating curves have a power-law form (i.e., C = aQb, where a and b are fitted parameters). Two fundamental questions about the utility of these techniques are assessed in this paper: (i) How well to the parameters, a and b, characterize trends in the data? (ii) Are trends in rating curves diagnostic of changes to river water or sediment discharge? As noted in previous research, the offset parameter, a, is not an independent variable for most rivers, but rather strongly dependent on b and Q. Here it is shown that a is a poor metric for trends in the vertical offset of a rating curve, and a new parameter, â, as determined by the discharge-normalized power function [C = â (Q/QGM)b], where QGM is the geometric mean of the Q values sampled, provides a better characterization of trends. However, these techniques must be applied carefully, because curvature in the relationship between log(Q) and log(C), which exists for many rivers, can produce false trends in â and b. Also, it is shown that trends in â and b are not uniquely diagnostic of river water or sediment supply conditions. For example, an increase in â can be caused by an increase in sediment supply, a decrease in water supply, or a combination of these conditions. Large changes in water and sediment supplies can occur without any change in the parameters, â and b. Thus, trend analyses using sediment rating curves must include additional assessments of the time-dependent rates and trends of river water, sediment concentrations, and sediment discharge.

Atmospheric S and N deposition relates to increasing riverine transport of S and N in southwest China: Implications for soil acidification.

PubMed

Duan, Lei; Chen, Xiao; Ma, Xiaoxiao; Zhao, Bin; Larssen, Thorjørn; Wang, Shuxiao; Ye, Zhixiang

2016-11-01

Following Europe and North America, East Asia has become a global hotspot for acid deposition, with very high deposition of both sulfur (S) and nitrogen (N) occurring in large areas of southwest and southeast China. This study shows that the outflow flux of sulfate (SO 4 2- ) in three major tributaries of the Upper Yangtze River in the Sichuan Basin in southwest China has been increasing over the last three decades, which implies the regional soil acidification caused by increasing sulfur dioxide (SO 2 ) emissions. Since 2005, the outflow of SO 4 2- to the Upper Yangtze River from the Sichuan Basin has even reached the atmospheric SO 2 emission from the basin. In contrast to S emissions, the rapid increase in nitrogen (N) emissions, including nitrogen oxides (NOx) and ammonia (NH 3 ), have resulted in only a slight increase in nitrate (NO 3 - ) concentrations in surface waters, indicating a large retention of N in the basin. Although N deposition currently contributes much less than S to soil acidification in this area, it is possible that catchments receiving a high input of N may be unable to retain a large fraction of the N deposition over long periods. Copyright © 2016 Elsevier Ltd. All rights reserved.

Purification and Biochemical Characterization of Glutathione S-Transferase from Down Syndrome and Normal Children Erythrocytes: A Comparative Study

ERIC Educational Resources Information Center

Hamed, Ragaa R.; Maharem, Tahany M.; Abdel-Meguid, Nagwa; Sabry, Gilane M.; Abdalla, Abdel-Monem; Guneidy, Rasha A.

2011-01-01

Down syndrome (DS) is the phenotypic manifestation of trisomy 21. Our study was concerned with the characterization and purification of glutathione S-transferase enzyme (GST) from normal and Down syndrome (DS) erythrocytes to illustrate the difference in the role of this enzyme in the cell. Glutathione S-transferase and glutathione (GSH) was…

Prevalence and trends of leisure-time physical activity by occupation and industry in U.S. workers: the National Health Interview Survey 2004–2014

PubMed Central

Gu, Ja K.; Charles, Luenda E.; Ma, Claudia C.; Andrew, Michael E.; Fekedulegn, Desta; Hartley, Tara A.; Violanti, John M.; Burchfiel, Cecil M.

2016-01-01

Purpose Studies describing prevalence and trends of physical activity among workers in the United States are scarce. We aimed to estimate prevalence and trends of “sufficient” leisure-time physical activity (LTPA) during the 2004–2014 time period among U.S. workers. Methods Data were collected for U.S. workers in the National Health Interview Survey. LTPA was categorized as sufficiently active (moderate intensity, ≥150 minutes per week), insufficiently active (10–149 minutes per week), and inactive (<10 minutes per week). Prevalence of LTPA was adjusted for age using 2010 U.S. working population as a standardized age distribution. Results Prevalence trends of “sufficient” LTPA significantly increased from 2004 to 2014 (45.6% to 54.8%; P < .001). Among industry groups, the highest prevalence of “sufficient” LTPA was observed among workers in Professional/Scientific/Technical Services (62.1%). The largest increases were observed among workers in Public Administration (51.3%–63.4%). Among occupational groups, “sufficient” LTPA prevalence was lowest in farming/fishing/forestry (30.8%) and highest in life/physical/social science (66.4%). Prevalence of LTPA significantly increased from 2004 to 2014 in most occupational and industry groups. Conclusions Among U.S. workers, trends of “sufficient” LTPA significantly increased between 2004 and 2014. Overall, a larger proportion of white-collar compared to blue-collar workers were engaged in “sufficient” LTPA. PMID:27659584

Variability and trend in ozone over the southern tropics and subtropics

NASA Astrophysics Data System (ADS)

Toihir, Abdoulwahab Mohamed; Portafaix, Thierry; Sivakumar, Venkataraman; Bencherif, Hassan; Pazmiño, Andréa; Bègue, Nelson

2018-03-01

Long-term variability in ozone trends was assessed over eight Southern Hemisphere tropical and subtropical sites (Natal, Nairobi, Ascension Island, Java, Samoa, Fiji, Reunion and Irene), using total column ozone data (TCO) and vertical ozone profiles (altitude range 15-30 km) recorded during the period January 1998-December 2012. The TCO datasets were constructed by combination of satellite data (OMI and TOMS) and ground-based observations recorded using Dobson and SAOZ spectrometers. Vertical ozone profiles were obtained from balloon-sonde experiments which were operated within the framework of the SHADOZ network. The analysis in this study was performed using the Trend-Run model. This is a multivariate regression model based on the principle of separating the variations of ozone time series into a sum of several forcings (annual and semi-annual oscillations, QBO (Quasi-Biennial Oscillation), ENSO, 11-year solar cycle) that account for most of its variability. The trend value is calculated based on the slope of a normalized linear function which is one of the forcing parameters included in the model. Three regions were defined as follows: equatorial (0-10° S), tropical (10-20° S) and subtropical (20-30° S). Results obtained indicate that ozone variability is dominated by seasonal and quasi-biennial oscillations. The ENSO contribution is observed to be significant in the tropical lower stratosphere and especially over the Pacific sites (Samoa and Java). The annual cycle of ozone is observed to be the most dominant mode of variability for all the sites and presents a meridional signature with a maximum over the subtropics, while semi-annual and quasi-biannual ozone modes are more apparent over the equatorial region, and their magnitude decreases southward. The ozone variation mode linked to the QBO signal is observed between altitudes of 20 and 28 km. Over the equatorial zone there is a strong signal at ˜ 26 km, where 58 % ±2 % of total ozone variability is

Temporal trends and spatial patterns in nutrient export along the Mississippi River and its Tributaries

NASA Astrophysics Data System (ADS)

Stewart, B.; Li, L.

2017-12-01

The Mississippi River, the largest river in the U. S., exports excessive nutrients from the land to the sea, causing the problem of hypoxia in the Gulf of Mexico. In this research, we examined nutrient export along the Mississippi River and its tributaries to understand its trends and patterns and to identify the major factors contributing to these trends. We examined nutrient data from 1950 - 2017 for four sites along the Mississippi River and four tributary sites from the U. S. Geological Survey. The species included: total nitrogen, organic nitrogen, ammonia, nitrate, orthophosphate, and phosphorous. We analyzed the power law relationship of concentration and discharge, for which the export of nutrient species exhibited several trends. Both nitrogen (N) and phosphorous (P) species exhibited mostly chemodynamic behavior. This is in contrast to previous observations in smaller agricultural land where N and P export was mostly chemostatic with no significant change in concentration as discharge varies, suggesting possible scaling effects at different spatial scales. We also compared the average annual concentration over time at each site. The N concentration decreased from upstream to downstream, likely due to greater agricultural activities in the upstream Mississippi river and possible denitrification along the river. The N concentration also increased with time. The P species, however, fluctuated from site to site with no clear spatial patterns, but consistently exhibited higher concentrations at upstream sites with greater agricultural activities. The P species also fluctuated over time, likely due to patterns in discharge and agricultural activities. The results of this research can be further explored by calculating the total export of nutrients into the Gulf of Mexico to determine limits and drivers of nutrient export for better water management, thus helping prevent hypoxia and eutrophication within the Mississippi River basin.

Attentional Bias and the Development of Cerebral Dominance in Normal and Learning Disabled Children.

ERIC Educational Resources Information Center

Hynd, George W.; And Others

The magnitude of the dichotic right ear advantage was assessed in 48 normal and 48 learning disabled (LD) children (mean age 8.3 years). Ss were matched according to age, sex, and handedness. An analysis of results indicated a significant right ear advantage in both the normal and LD children, but revealed no developmental trend for either group.…

Trend Analysis of Total Ozone Data.

NASA Astrophysics Data System (ADS)

Harris, Neil Richard Peter

The total column ozone data for many Dobson stations are examined for the existence of long-term changes, principally in the period 1965-1986. Analysis of the measurements taken at Arosa, Switzerland from August 1931 to July 1988 reveals a statistically significant wintertime loss in recent years of about 6% compared to historic values. Examination of data from several other ground stations gave similar results, and in addition incongruous features were found in many of the published records. Bojkov (1987/8) produced a set of Provisionally Revised data by adjusting the data using information about the Dobson instrument calibrations made available by the individual stations. Similar winter -time losses are found in an analysis of this Provisionally Revised set of data as are found in the published data. Multiple regression analyses were performed using a model which seeks trends on a monthly basis after allowance for the effects of the solar cycle and the quasi-biennial oscillation. Between 1969 and 1986 the observed decreases in total column ozone in three latitude bands from 30^circ N to 64^circN ranged from -2.3% at the lower latitudes to -6.2% at the higher latitudes during the winter (December through March) and from -0.2% to -1.9% in the summer (May through August). Sensitivity studies are presented which show the robustness of these results to such factors as the length of time considered, the solar cycle, the injection of nitrogen oxides by the nuclear bomb tests which were carried out in the atmosphere in the early 1960's, and the assumed nature of the loss. The seasonal and the latitudinal variations of these losses are qualitatively similar to the predictions of the current 2-D photochemical models of the atmosphere. However the observed losses are greater than the predicted losses by as much as a factor of four at 60^circ N in winter. Finally there is some evidence for longitudinal variations in both the observed trends and in the observed response of

The neuropsychology of normal aging and preclinical Alzheimer’s disease

PubMed Central

Caselli, Richard J.; Locke, Dona E.C.; Dueck, Amylou C.; Knopman, David S.; Woodruff, Bryan K.; Hoffman-Snyder, Charlene; Rademakers, Rosa; Fleisher, Adam S.; Reiman, Eric M.

2013-01-01

Background An NIA-sponsored workgroup on preclinical Alzheimer’s disease (AD) articulated the need to characterize cognitive differences between normal aging and preclinical AD. Methods 71 apolipoprotein E (APOE) e4 homozygotes (HMZ), 194 e3/4 heterozygotes (HTZ), and 356 e4 noncarriers (NC) aged 21–87 years who were cognitively healthy underwent neuropsychological testing every two years. Longitudinal trajectories of test scores were compared between APOE subgroups. Results There was a significant effect of age on all cognitive domains in both APOE e4 carriers and NC. A significant effect of APOE e4 gene dose was confined to the memory domain and the Dementia Rating Scale. Cross sectional comparisons did not discriminate the groups. Conclusions While cognitive aging patterns are similar in APOE e4 carriers and NC, preclinical AD is characterized by a significant e4 gene dose effect that impacts memory and is detectable longitudinally. Preclinical neuropsychological testing strategies should emphasize memory sensitive measures and longitudinal design. PMID:23541188

Redescription of Synthesium pontoporiae n. comb. with notes on S. tursionis and S. seymouri n. comb. (Digenea: Brachycladiidae Odhner, 1905).

PubMed

Marigo, Juliana; Vicente, Ana Carolina Paulo; Valente, Ana Luisa Schifino; Measures, Lena; Santos, Cláudia Portes

2008-04-01

Synthesium pontoporiae n. comb. is redescribed, together with Synthesium tursionis and Synthesium seymouri n. comb.; the parasites were obtained from stranded and accidentally caught cetaceans. The sucker ratio (ratio between widths of the oral and ventral suckers) in S. pontoporiae was 1:1.8-3.0 (mean 1:2.2); in S. tursionis was 1:0.8-1.2; and in S. seymouri was 1:0.5-0.7. Synthesium pontoporiae differed from its congeners by additional diagnostic characters, including: oval to lobed testes; small cirrus with pyriform proximal region and flexible, tubular distal region formed by evagination of ejaculatory duct; and vitellarium in small follicles extending from the level of the seminal vesicle to the posterior extremity of the body and not forming dendritic radial bunches. Data on the morphology of adult S. pontoporiae and S. tursionis were inferred from confocal laser microscopical observations.

Passive microrheology of normal and cancer cells after ML7 treatment by atomic force microscopy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lyapunova, Elena, E-mail: lyapunova@icmm.ru; Ural Federal University, Kuibyishev Str. 48, Ekaterinburg, 620000; Nikituk, Alexander, E-mail: nas@icmm.ru

Mechanical properties of living cancer and normal thyroidal cells were investigated by atomic force microscopy (AFM). Cell mechanics was compared before and after treatment with ML7, which is known to reduce myosin activity and induce softening of cell structures. We recorded force curves with extended dwell time of 6 seconds in contact at maximum forces from 500 pN to 1 nN. Data were analyzed within different frameworks: Hertz fit was applied in order to evaluate differences in Young’s moduli among cell types and conditions, while the fluctuations of the cantilever in contact with cells were analyzed with both conventional algorithmsmore » (probability density function and power spectral density) and multifractal detrended fluctuation analysis (MF-DFA). We found that cancer cells were softer than normal cells and ML7 had a substantial softening effect on normal cells, but only a marginal one on cancer cells. Moreover, we observed that all recorded signals for normal and cancer cells were monofractal with small differences between their scaling parameters. Finally, the applicability of wavelet-based methods of data analysis for the discrimination of different cell types is discussed.« less

Delayed Audiovisual Integration of Patients with Mild Cognitive Impairment and Alzheimer’s Disease Compared with Normal Aged Controls

PubMed Central

Wu, Jinglong; Yang, Jiajia; Yu, Yinghua; Li, Qi; Nakamura, Naoya; Shen, Yong; Ohta, Yasuyuki; Yu, Shengyuan; Abe, Koji

2013-01-01

The human brain can anatomically combine task-relevant information from different sensory pathways to form a unified perception; this process is called multisensory integration. The aim of the present study was to test whether the multisensory integration abilities of patients with mild cognitive impairment (MCI) and Alzheimer’s disease (AD) differed from those of normal aged controls (NC). A total of 64 subjects were divided into three groups: NC individuals (n = 24), MCI patients (n = 19), and probable AD patients (n = 21). All of the subjects were asked to perform three separate audiovisual integration tasks and were instructed to press the response key associated with the auditory, visual, or audiovisual stimuli in the three tasks. The accuracy and response time (RT) of each task were measured, and the RTs were analyzed using cumulative distribution functions to observe the audiovisual integration. Our results suggest that the mean RT of patients with AD was significantly longer than those of patients with MCI and NC individuals. Interestingly, we found that patients with both MCI and AD exhibited adequate audiovisual integration, and a greater peak (time bin with the highest percentage of benefit) and broader temporal window (time duration of benefit) of multisensory enhancement were observed. However, the onset time and peak benefit of audiovisual integration in MCI and AD patients occurred significantly later than did those of the NC. This finding indicates that the cognitive functional deficits of patients with MCI and AD contribute to the differences in performance enhancements of audiovisual integration compared with NC. PMID:22810093

Charge imbalance and Josephson effects in superconductor-normal metal mesoscopic structures

NASA Astrophysics Data System (ADS)

Volkov, A. F.

2007-11-01

We consider a SBS Josephson junction the superconducting electrodes S of which are in contact with normal metal reservoirs ( B means a barrier). For temperatures near Tc we calculate an effective critical current Ic* and the resistance of the system at the currents IN reservoirs into the S wire, affects essentially the characteristics of the structure. The effective critical current Ic* is always larger than the critical current Ic in the absence of the normal reservoirs and increases with decreasing the ratio of the length of the S wire 2L to the charge imbalance relaxation length lQ . It is shown that a series of peaks arises on the I-V characteristics due to excitation of the Carlson-Goldman collective modes. We find the position of Shapiro steps which deviates from that given by the Josephson relation.

Insight into π-hole interactions containing the inorganic heterocyclic compounds S2N2/SN2P2.

PubMed

Lu, Bo; Zhang, Xueying; Meng, Lingpeng; Zeng, Yanli

2017-08-01

Similar to σ-hole interactions, the π-hole interaction has attracted much attention in recent years. According to the positive electrostatic potentials above and below the surface of inorganic heterocyclic compounds S 2 N 2 and three SN 2 P 2 isomers (heterocyclic compounds 1-4), and the negative electrostatic potential outside the X atom of XH 3 (X = N, P, As), S 2 N 2 /SN 2 P 2 ⋯XH 3 (X = N, P, As) complexes were constructed and optimized at the MP2/aug-cc-pVTZ level. The X atom of XH 3 (X = N, P, As) is almost perpendicular to the ring of the heterocyclic compounds. The π-hole interaction energy becomes greater as the trend goes from 1⋯XH 3 to 4⋯XH 3 . These π-hole interactions are weak and belong to "closed-shell" noncovalent interactions. According to the energy decomposition analysis, of the three attractive terms, the dispersion energy contributes more than the electrostatic energy. The polarization effect also plays an important role in the formation of π-hole complexes, with the contrasting phenomena of decreasing electronic density in the π-hole region and increasing electric density outside the X atom of XH 3 (X = N, P, As). Graphical abstract Computed density difference plots for the complexes 3⋯NH 3 (a 1 ), 3⋯PH 3 (b 1 ), 3⋯AsH 3 (c 1 ) and electron density shifts for the complexes 3⋯NH 3 (a 2 ), 3⋯PH 3 (b 2 ),3⋯AsH 3 (c 2 ) on the 0.001 a.u. contour.

Assessment of atmospheric acidified pollutants trends observed by EANET in North-East Asia in the first decade of XXI century

NASA Astrophysics Data System (ADS)

Gromov, Sergey A.; Trifonova-Yakovleva, Alisa; Gromov, Sergey S.

2015-04-01

pattern, viz. an eastward increase in trend magnitudes in the north-south direction. We further identify special cases of statistically significant seasonal trends for the series that otherwise do not exhibit apparent long-term dynamics, i.e. show an insignificant overall trend. A case in point is the NH3 observational record at Mondy station (Russia), for which the spring-summer negative trends are comparable to the winter positive trends, and both significant. Finally, we discuss and compare these first results with an evaluation of changes in acid deposition over region from 2000 provided by WMO PC-SAG in its global wet deposition assessment (Vet et al., 2014). References: Vet, R., Artz, R. S., Carou, S., Shaw, M., Ro, C. U., Aas, W., Baker, A., Bowersox, V. C., Dentener, F., Galy Lacaux, C., Hou, A., Pienaar, J. J., Gillett, R., Forti, M. C., Gromov, S., Hara, H., Khodzher, T., Mahowald, N. M., Nickovic, S., Rao, P. S. P., and Reid, N. W.: A global assessment of precipitation chemistry and deposition of sulfur, nitrogen, sea salt, base cations, organic acids, acidity and pH, and phosphorus. Atmos. Environ., 93, 3-100, 2014.

Response to “Worrying Trends in Econophysics”

NASA Astrophysics Data System (ADS)

McCauley, Joseph L.

2006-11-01

This article is a response to the recent “Worrying Trends in Econophysics” critique written by four respected theoretical economists [M. Gallegatti, S. Keen, T. Lux, P. Ormerod, Worrying trends in econophysics, Physica A (2006), submitted for publication [1

Power of tests for comparing trend curves with application to national immunization survey (NIS).

PubMed

Zhao, Zhen

2011-02-28

To develop statistical tests for comparing trend curves of study outcomes between two socio-demographic strata across consecutive time points, and compare statistical power of the proposed tests under different trend curves data, three statistical tests were proposed. For large sample size with independent normal assumption among strata and across consecutive time points, the Z and Chi-square test statistics were developed, which are functions of outcome estimates and the standard errors at each of the study time points for the two strata. For small sample size with independent normal assumption, the F-test statistic was generated, which is a function of sample size of the two strata and estimated parameters across study period. If two trend curves are approximately parallel, the power of Z-test is consistently higher than that of both Chi-square and F-test. If two trend curves cross at low interaction, the power of Z-test is higher than or equal to the power of both Chi-square and F-test; however, at high interaction, the powers of Chi-square and F-test are higher than that of Z-test. The measurement of interaction of two trend curves was defined. These tests were applied to the comparison of trend curves of vaccination coverage estimates of standard vaccine series with National Immunization Survey (NIS) 2000-2007 data. Copyright © 2011 John Wiley & Sons, Ltd.

Trends in U.S., Past-Year Marijuana Use from 1985–2009; An Age-Period-Cohort Analysis

PubMed Central

Miech, Richard; Koester, Stephen

2014-01-01

Background We present a formal age-period-cohort analysis to examine if the recent increase in past-year marijuana use among the young is specific to the younger generation or if, instead, it is part of a general increase present across cohorts of all ages. This is the first age-period-cohort analysis of past-year marijuana use that includes adult trends from 2001–09. Methods Data come from the National Survey on Drug Use and Health, a series of annual, nationally-representative, cross-sectional surveys of the U.S. civilian, non-institutionalized population. The analysis focuses on the 25 year time span from 1985–2009 and uses the recently developed ‘intrinsic estimator’ algorithm to estimate independent effects of age, period, and cohort. Results The recent increase in past-year marijuana use is not unique to the youngest birth cohorts. An independent, positive influence of cohort membership on past-year marijuana use, net of historical period and age effects, is smaller for today’s youngest cohorts than it was for the cohorts that came immediately before, and, in fact, is at its lowest level in three decades. The recent increase in marijuana use among the young is more consistent with a historical period effect that has acted across all cohorts. Period and cohort trends differ substantially for Hispanics. Conclusions The major forces that drive trends in past-year marijuana use are moving away from cohort-specific factors and toward broad-based influences that affect cohorts of all ages. Strategic public health and policy efforts aimed at countering the recent increase in past-year marijuana use should do the same. PMID:22361212

The Trend Odds Model for Ordinal Data‡

PubMed Central

Capuano, Ana W.; Dawson, Jeffrey D.

2013-01-01

Ordinal data appear in a wide variety of scientific fields. These data are often analyzed using ordinal logistic regression models that assume proportional odds. When this assumption is not met, it may be possible to capture the lack of proportionality using a constrained structural relationship between the odds and the cut-points of the ordinal values (Peterson and Harrell, 1990). We consider a trend odds version of this constrained model, where the odds parameter increases or decreases in a monotonic manner across the cut-points. We demonstrate algebraically and graphically how this model is related to latent logistic, normal, and exponential distributions. In particular, we find that scale changes in these potential latent distributions are consistent with the trend odds assumption, with the logistic and exponential distributions having odds that increase in a linear or nearly linear fashion. We show how to fit this model using SAS Proc Nlmixed, and perform simulations under proportional odds and trend odds processes. We find that the added complexity of the trend odds model gives improved power over the proportional odds model when there are moderate to severe departures from proportionality. A hypothetical dataset is used to illustrate the interpretation of the trend odds model, and we apply this model to a Swine Influenza example where the proportional odds assumption appears to be violated. PMID:23225520

The trend odds model for ordinal data.

PubMed

Capuano, Ana W; Dawson, Jeffrey D

2013-06-15

Ordinal data appear in a wide variety of scientific fields. These data are often analyzed using ordinal logistic regression models that assume proportional odds. When this assumption is not met, it may be possible to capture the lack of proportionality using a constrained structural relationship between the odds and the cut-points of the ordinal values. We consider a trend odds version of this constrained model, wherein the odds parameter increases or decreases in a monotonic manner across the cut-points. We demonstrate algebraically and graphically how this model is related to latent logistic, normal, and exponential distributions. In particular, we find that scale changes in these potential latent distributions are consistent with the trend odds assumption, with the logistic and exponential distributions having odds that increase in a linear or nearly linear fashion. We show how to fit this model using SAS Proc NLMIXED and perform simulations under proportional odds and trend odds processes. We find that the added complexity of the trend odds model gives improved power over the proportional odds model when there are moderate to severe departures from proportionality. A hypothetical data set is used to illustrate the interpretation of the trend odds model, and we apply this model to a swine influenza example wherein the proportional odds assumption appears to be violated. Copyright © 2012 John Wiley & Sons, Ltd.

Temporal Trends in Phthalate Exposures: Findings from the National Health and Nutrition Examination Survey, 2001–2010

PubMed Central

Calafat, Antonia M.; Woodruff, Tracey J.

2014-01-01

Background: Phthalates are ubiquitous environmental contaminants. Because of potential adverse effects on human health, butylbenzyl phthalate [BBzP; metabolite, monobenzyl phthalate (MBzP)], di-n-butyl phthalate [DnBP; metabolite, mono-n-butyl phthalate (MnBP)], and di(2-ethylhexyl) phthalate (DEHP) are being replaced by substitutes including other phthalates; however, little is known about consequent trends in population-level exposures. Objective: We examined temporal trends in urinary concentrations of phthalate metabolites in the general U.S. population and whether trends vary by sociodemographic characteristics. Methods: We combined data on 11 phthalate metabolites for 11,071 participants from five cycles of the National Health and Nutrition Examination Survey (2001–2010). Percent changes and least square geometric means (LSGMs) were calculated from multivariate regression models. Results: LSGM concentrations of monoethyl phthalate, MnBP, MBzP, and ΣDEHP metabolites decreased between 2001–2002 and 2009–2010 [percent change (95% CI): –42% (–49, –34); –17% (–23, –9); –32% (–39, –23) and –37% (–46, –26), respectively]. In contrast, LSGM concentrations of monoisobutyl phthalate, mono(3-carboxypropyl) phthalate (MCPP), monocarboxyoctyl phthalate, and monocarboxynonyl phthalate (MCNP) increased over the study period [percent change (95% CI): 206% (178, 236); 25% (8, 45); 149% (102, 207); and 15% (1, 30), respectively]. Trends varied by subpopulations for certain phthalates. For example, LSGM concentrations of ΣDEHP metabolites, MCPP, and MCNP were higher in children than adults, but the gap between groups narrowed over time (pinteraction < 0.01). Conclusions: Exposure of the U.S. population to phthalates has changed in the last decade. Data gaps make it difficult to explain trends, but legislative activity and advocacy campaigns by nongovernmental organizations may play a role in changing trends. Citation: Zota AZ, Calafat AM

Trends of influenza infection in Suriname

PubMed Central

Adhin, Malti R.; Grunberg, Meritha; Labadie‐Bracho, Mergiory

2012-01-01

Please cite this paper as: Adhin et al. (2012) Trends of Influenza infection in Suriname. Influenza and Other Respiratory Viruses DOI: 10.1111/irv.12037. The trends of influenza infection in Suriname were assessed from February 2010 through February 2011. Testing of 393 patients with symptoms of acute respiratory infection (ARI) revealed 15·3% Influenza B and 18·6% could be identified as influenza A positive, consisting of 56% influenza A(H1N1)pdm09 and 44% seasonal A(H3N2). Influenza infection occurred throughout the year, and all three influenza types affected young children as the primary population. The annual incidence of A(H1N1)pdm09 was 6·88 per 100 000 inhabitants [CI] 4·87–9·45. The spread of influenza could neither be linked to tourist flow from the Netherlands nor to contact rates related to school schedules. PMID:23136977

Scoping study on trends in the economic value of electricity reliability to the U.S. economy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Eto, Joseph; Koomey, Jonathan; Lehman, Bryan

During the past three years, working with more than 150 organizations representing public and private stakeholders, EPRI has developed the Electricity Technology Roadmap. The Roadmap identifies several major strategic challenges that must be successfully addressed to ensure a sustainable future in which electricity continues to play an important role in economic growth. Articulation of these anticipated trends and challenges requires a detailed understanding of the role and importance of reliable electricity in different sectors of the economy. This report is intended to contribute to that understanding by analyzing key aspects of trends in the economic value of electricity reliability inmore » the U.S. economy. We first present a review of recent literature on electricity reliability costs. Next, we describe three distinct end-use approaches for tracking trends in reliability needs: (1) an analysis of the electricity-use requirements of office equipment in different commercial sectors; (2) an examination of the use of aggregate statistical indicators of industrial electricity use and economic activity to identify high reliability-requirement customer market segments; and (3) a case study of cleanrooms, which is a cross-cutting market segment known to have high reliability requirements. Finally, we present insurance industry perspectives on electricity reliability as an example of a financial tool for addressing customers' reliability needs.« less

Somatosensory responses in normal aging, mild cognitive impairment, and Alzheimer’s disease

PubMed Central

Montaño, Rebecca; Donahue, Christopher H.; Adair, John C.; Knoefel, Janice; Qualls, Clifford; Hart, Blaine; Ranken, Doug; Aine, Cheryl J.

2010-01-01

As a part of a larger study of normal aging and Alzheimer’s disease (AD), which included patients with mild cognitive impairment (MCI), we investigated the response to median nerve stimulation in primary and secondary somatosensory areas. We hypothesized that the somatosensory response would be relatively spared given the reported late involvement of sensory areas in the progression of AD. We applied brief pulses of electric current to left and right median nerves to test the somato-sensory response in normal elderly (NE), MCI, and AD. MEG responses were measured and were analyzed with a semi-automated source localization algorithm to characterize source locations and timecourses. We found an overall difference in the amplitude of the response of the primary somatosensory source (SI) based on diagnosis. Across the first three peaks of the SI response, the MCI patients exhibited a larger amplitude response than the NE and AD groups (P < 0.03). Additional relationships between neuropsychological measures and SI amplitude were also determined. There was no significant difference in amplitude for the contralateral secondary somatosensory source across diagnostic category. These results suggest that somatosensory cortex is affected early in the progression of AD and may have some consequence on behavioral and functional measures. PMID:20013008

S-Wave Normal Mode Propagation in Aluminum Cylinders

USGS Publications Warehouse

Lee, Myung W.; Waite, William F.

2010-01-01

Large amplitude waveform features have been identified in pulse-transmission shear-wave measurements through cylinders that are long relative to the acoustic wavelength. The arrival times and amplitudes of these features do not follow the predicted behavior of well-known bar waves, but instead they appear to propagate with group velocities that increase as the waveform feature's dominant frequency increases. To identify these anomalous features, the wave equation is solved in a cylindrical coordinate system using an infinitely long cylinder with a free surface boundary condition. The solution indicates that large amplitude normal-mode propagations exist. Using the high-frequency approximation of the Bessel function, an approximate dispersion relation is derived. The predicted amplitude and group velocities using the approximate dispersion relation qualitatively agree with measured values at high frequencies, but the exact dispersion relation should be used to analyze normal modes for full ranges of frequency of interest, particularly at lower frequencies.

Monooxorhenium(V) complexes with 222-N2S2 MAMA ligands for bifunctional chelator agents: Syntheses and preliminary in vivo evaluation

PubMed Central

Demoin, Dustin Wayne; Dame, Ashley N.; Minard, William D.; Gallazzi, Fabio; Seickman, Gary L.; Rold, Tammy L.; Bernskoetter, Nicole; Fassbender, Michael E.; Hoffman, Timothy J.; Deakyne, Carol A.; Jurisson, Silvia S.

2016-01-01

Introduction Targeted radiotherapy using the bifunctional chelate approach with 186/188Re(V) is challenging because of the susceptibility of monooxorhenium(V)-based complexes to oxidize in vivo at high dilution. A monoamine-monoamide dithiol (MAMA)-based bifunctional chelating agent was evaluated with both rhenium and technetium to determine its utility for in vivo applications. Methods A 222-MAMA chelator, 222-MAMA(N-6-Ahx-OEt) bifunctional chelator, and 222- MAMA(N-6-Ahx-BBN(7-14)NH2) were synthesized, complexed with rhenium, radiolabeled with 99mTc and 186Re (carrier added and no carrier added), and evaluated in initial biological distribution studies. Results An IC50 value of 2.0 ± 0.7 nM for natReO-222-MAMA(N-6-Ahx-BBN(7-14)NH2) compared to [125I]-Tyr4-BBN(NH2) was determined through competitive cell binding assays with PC-3 tumor cells. In vivo evaluation of the no-carrier added 99mTc-222-N2S2(N-6-Ahx-BBN(7-14)NH2) complex showed little gastric uptake and blockable pancreatic uptake in normal mice. Conclusions The 186ReO-222-N2S2(N-6-Ahx-BBN(7-14)NH2) complex showed stability in biological media, which indicates that the 222-N2S2 chelator is appropriate for chelating 186/188Re in radiopharmaceuticals involving peptides. Additionally, the in vitro cell studies showed that the ReO-222-N2S2(N-6-Ahx-BBN(7-14)NH2) complex (macroscopically) bound to PC3-tumor cell surface receptors with high affinity. The 99mTc analog was stable in vivo and exhibited pancreatic uptake in mice that was blockable, indicating BB2r targeting. PMID:27694058

Response of surface water chemistry to reduced levels of acid precipitation: Comparison of trends in two regions of New York, USA

USGS Publications Warehouse

Burns, Douglas A.; McHale, M.R.; Driscoll, C.T.; Roy, K.M.

2006-01-01

In light of recent reductions in sulphur (S) and nitrogen (N) emissions mandated by Title IV of the Clean Air Act Amendments of 1990, temporal trends and trend coherence in precipitation (1984-2001 and 1992-2001) and surface water chemistry (1992-2001) were determined in two of the most acid-sensitive regions of North America, i.e. the Catskill and Adirondack Mountains of New York. Precipitation chemistry data from six sites located near these regions showed decreasing sulphate (SO42-), nitrate (NO3-), and base cation (CB) concentrations and increasing pH during 1984-2001, but few significant trends during 1992-2001. Data from five Catskill streams and 12 Adirondack lakes showed decreasing trends in SO42- concentrations at all sites, and decreasing trends in NO3-, CB, and H+ concentrations and increasing trends in dissolved organic carbon at most sites. In contrast, acid-neutralizing capacity (ANC increased significantly at only about half the Adirondack lakes and in one of the Catskill streams. Flow correction prior to trend analysis did not change any trend directions and had little effect on SO42- trends, but it caused several significant non-flow-corrected trends in NO3- and ANC to become non-significant, suggesting that trend results for flow-sensitive constituents are affected by flow-related climate variation. SO42- concentrations showed high temporal coherence in precipitation, surface waters, and in precipitation-surface water comparisons, reflecting a strong link between S emissions, precipitation SO42- concentrations, and the processes that affect S cycling within these regions. NO3- and H+ concentrations and ANC generally showed weak coherence, especially in surface waters and in precipitation-surface water comparisons, indicating that variation in local-scale processes driven by factors such as climate are affecting trends in acid-base chemistry in these two regions. Copyright ?? 2005 John Wiley & Sons, Ltd.

Cocrystals of 6-propyl-2-thiouracil: N-H···O versus N-H···S hydrogen bonds.

PubMed

Tutughamiarso, Maya; Egert, Ernst

2011-11-01

In order to investigate the relative stability of N-H···O and N-H···S hydrogen bonds, we cocrystallized the antithyroid drug 6-propyl-2-thiouracil with two complementary heterocycles. In the cocrystal pyrimidin-2-amine-6-propyl-2-thiouracil (1/2), C(4)H(5)N(3)·2C(7)H(10)N(2)OS, (I), the `base pair' is connected by one N-H···S and one N-H···N hydrogen bond. Homodimers of 6-propyl-2-thiouracil linked by two N-H···S hydrogen bonds are observed in the cocrystal N-(6-acetamidopyridin-2-yl)acetamide-6-propyl-2-thiouracil (1/2), C(9)H(11)N(3)O(2)·2C(7)H(10)N(2)OS, (II). The crystal structure of 6-propyl-2-thiouracil itself, C(7)H(10)N(2)OS, (III), is stabilized by pairwise N-H···O and N-H···S hydrogen bonds. In all three structures, N-H···S hydrogen bonds occur only within R(2)(2)(8) patterns, whereas N-H···O hydrogen bonds tend to connect the homo- and heterodimers into extended networks. In agreement with related structures, the hydrogen-bonding capability of C=O and C=S groups seems to be comparable.

Elliptic flow in heavy-ion collisions at energies √{sN N}=2.7 - 39 GeV

NASA Astrophysics Data System (ADS)

Ivanov, Yu. B.; Soldatov, A. A.

2015-02-01

The transverse-momentum-integrated elliptic flow of charged particles at midrapidity, v2(charged), and that of identified hadrons from Au +Au collisions are computed in a wide range of incident energies 2.7 ≤√{sN N}≤ 39 GeV. The simulations are performed within a three-fluid model by employing three different equations of state (EoSs): a purely hadronic EoS and two versions of the EoS involving the deconfinement transition—a first-order phase transition and a smooth crossover one. The present simulations demonstrate low sensitivity of v2(charged) to the EoS. All considered scenarios equally well reproduce recent STAR data on v2(charged) for mid-central Au +Au collisions and properly describe its change of sign at the incident energy decrease below √{sN N}≈ 3.5 GeV. The predicted integrated elliptic flow of various species exhibits a stronger dependence on the EoS. A noticeable sensitivity to the EoS is found for antibaryons and, to a lesser extent, for K- mesons. In particular, the v2 excitation functions of antibaryons exhibit a nonmonotonicity within the deconfinement scenarios that was predicted by Kolb, Sollfrank, and Heinz. However, low multiplicities of antibaryons at √{sN N}≤ 10 GeV result in large fluctuations of their v2, which may wash out this nonmonotonicity.

Integer ratios of S{sub n}/E{sub n} in {sup 40}Ca+n resonances suggesting two-oscillator excitations in the target nucleus

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ohkubo, Makio

2009-08-15

In s-wave neutron resonances of {sup 40}Ca at E{sub n}{<=}2.5 MeV, S{sub n}/E{sub n} for many levels is found to be of the form 17(n/m) where n, m are small integers. Statistical tests show small probabilities for the observed dispositions of many levels at E{sub n}=(j/k)(1/70)G (j, k; small integers). To meet the requirement of time periodicity of the compound nucleus at resonance, a breathing model is developed, where the excitation energies E{sub x} are written as a sum of inverse integers; E{sub x}=S{sub n}+E{sub n}=G{sigma}(1/k) (k: integer). In {sup 40}Ca+n, the separation energy S{sub n}=8362 keV is written asmore » S{sub n}=(17/70)G=(1/7+1/10)G, where G=34.4 MeV. G is almost equal to the Fermi energy of the nucleus. It is suggested that two oscillators of energy (1/7)G and (1/10)G are excited in {sup 40}Ca by neutron incidence, in which the recurrence energy (1/70)G is resonant with neutrons of energies at (j/k)(1/70)G, forming a simple compound nucleus.« less

ASERNIP-S: international trend setting.

PubMed

Maddern, Guy; Boult, Margaret; Ahern, Eleanor; Babidge, Wendy

2008-10-01

The Australian Safety and Efficacy Register of New Interventional Procedures--Surgical (ASERNIP-S) came into being 10 years ago to provide health technology assessments specifically tailored towards new surgical techniques and technologies. It was and remains the only organisation in the world to focus on this area of research. Most funding has been provided by the Australian Government Department of Health, and assessments have helped inform the introduction of new surgical techniques into Australia. ASERNIP-S is a project of the Royal Australasian College of Surgeons. The ASERNIP-S program employs a diverse range of methods including systematic reviews, technology overviews, assessments of new and emerging surgical technologies identified by horizon scanning, and audit. Support and guidance for the program is provided by Fellows of the Royal Australasian College of Surgeons. ASERNIP-S works closely with consumers to produce health technology assessments and audits, as well as consumer information to keep patients fully informed of research. Since its inception, the ASERNIP-S program has developed a strong international profile through the production of over 60 reports on evidence-based surgery, surgical technologies and audit. The work undertaken by ASERNIP-S has evolved from assessments of the safety and efficacy of procedures to include guidance on policies and surgical training programs. ASERNIP-S needs to secure funding so that it can continue to play an integral role in the improvement of quality of care both in Australia and internationally.

Trends in atmospheric ammonium concentrations in relation to atmospheric sulfate and local agriculture.

PubMed

Kelly, Victoria R; Lovett, Gary M; Weathers, Kathleen C; Likens, Gene E

2005-06-01

Ammonium (NH(4)(+)) concentrations in air and precipitation at the Institute of Ecosystem Studies (IES) in southeastern New York, USA declined over an 11-year period from 1988 to 1999, but increased from 1999 to 2001. These trends in particulate NH(4)(+) correlated well with trends in particulate SO(4)(2-) over the 1988-2001 period. The NH(4)(+) trends were not as well correlated with local cattle and milk production, which declined continuously throughout the period. This suggests that regional transport of SO(4)(2-) may have a greater impact on concentrations of NH(4)(+) and subsequent deposition than local agricultural emissions of NH(3). Ammonium concentrations in precipitation correlated significantly with precipitation SO(4)(2-) concentrations for the 1984-2001 period although NH(4)(+) in precipitation increased after 1999 and SO(4)(2-) in precipitation continued to decline after 1999. The correlation between NH(4)(+) and SO(4)(2-) was stronger for particulates than for precipitation. Particulate NH(4)(+) concentrations were also correlated with particulate SO(4)(2-) concentrations at 31 of 35 eastern U.S. CASTNet sites that had at least 10 years of data. Air concentrations of NH(4)(+) and SO(4)(2-) were more strongly correlated at the sites that were located within an agricultural landscape than in forested sites. At most of the sites there was either no trend or a decrease in NH(4)(+) dry deposition during the 1988-2001 period. The sites that showed an increasing trend in NH(4)(+) dry deposition were generally located in the southeastern U.S. The results of this study suggest that, in the northeastern U.S., air concentrations of NH(4)(+) and subsequent deposition may be more closely linked to SO(4)(2-) and thus SO(2) emissions than with NH(3) emissions. These results also suggest that reductions in S emissions have reduced NH(4)(+) transport to and NH(4)(+)-N deposition in the Northeast.

Maternal serum soluble CD30 is increased in normal pregnancy, but decreased in preeclampsia and small for gestational age pregnancies.

PubMed

Kusanovic, Juan Pedro; Romero, Roberto; Hassan, Sonia S; Gotsch, Francesca; Edwin, Samuel; Chaiworapongsa, Tinnakorn; Erez, Offer; Mittal, Pooja; Mazaki-Tovi, Shali; Soto, Eleazar; Than, Nandor Gabor; Friel, Lara A; Yoon, Bo Hyun; Espinoza, Jimmy

2007-12-01

Women with preeclampsia and those who deliver small for gestational age (SGA) neonates are characterized by intravascular inflammation (T helper 1 (Th1)-biased immune response). There is controversy about the T helper 2 (Th2) response in preeclampsia and SGA. CD30, a member of the tumor necrosis factor receptor superfamily, is preferentially expressed in vitro and in vivo by activated T cells producing Th2-type cytokines. Its soluble form (sCD30) has been proposed to be an index of Th2 immune response. The objective of this study was to determine whether the maternal serum concentration of sCD30 changes with normal pregnancy, as well as in mothers with preeclampsia and those who deliver SGA neonates. This cross-sectional study included patients in the following groups: (1) non-pregnant women (N = 49); (2) patients with a normal pregnancy (N = 89); (3) patients with preeclampsia (N = 100); and (4) patients who delivered an SGA neonate (N = 78). Maternal serum concentration of sCD30 was measured by a specific and sensitive enzyme-linked immunoassay. Non-parametric tests with post-hoc analysis were used for comparisons. A p value <0.05 was considered statistically significant. (1) The median sCD30 serum concentration of pregnant women was significantly higher than that of non-pregnant women (median 29.7 U/mL, range 12.2-313.2 vs. median 23.2 U/mL, range 14.6-195.1, respectively; p = 0.01). (2) Patients with preeclampsia had a significantly lower median serum concentration of sCD30 than normal pregnant women (median 24.7 U/mL, range 7.6-71.2 vs. median 29.7 U/mL, range 12.2-313.2, respectively; p < 0.05). (3) Mothers with SGA neonates had a lower median concentration of sCD30 than normal pregnant women (median 23.4 U/mL, range 7.1-105.3 vs. median 29.7 U/mL, range 12.2-313.2, respectively; p < 0.05). (4) There was no significant correlation (r = -0.059, p = 0.5) between maternal serum sCD30 concentration and gestational age (19-38 weeks) in normal pregnant women. (1

Maternal Serum Soluble CD30 Is Increased in Normal Pregnancy, but Decreased in Preeclampsia and Small for Gestational Age Pregnancies

PubMed Central

Kusanovic, Juan Pedro; Romero, Roberto; Hassan, Sonia S.; Gotsch, Francesca; Edwin, Samuel; Erez, Offer; Mittal, Pooja; Mazaki-Tovi, Shali; Soto, Eleazar; Than, Nandor Gabor; Friel, Lara A.; Chaiworapongsa, Tinnakorn; Yoon, Bo Hyun; Espinoza, Jimmy

2008-01-01

Objective Women with preeclampsia and those who deliver small for gestational age (SGA) neonates are characterized by intravascular inflammation (T helper 1 (Th1)-biased immune response). There is controversy about the T helper 2 (Th2) response in preeclampsia and SGA. CD30, a member of the tumor necrosis factor receptor superfamily, is preferentially expressed in vitro and in vivo by activated T cells producing Th2-type cytokines. Its soluble form (sCD30) has been proposed to be an index of Th2 immune response. The objective of this study was to determine whether maternal serum concentration of sCD30 changes with normal pregnancy, as well as in mothers with preeclampsia and those who deliver SGA neonates. Methods This cross-sectional study included patients in the following groups: (1) non-pregnant women (N=49); (2) patients with a normal pregnancy (N=89); (3) patients with preeclampsia (N=100); and (4) patients who delivered an SGA neonates (N=78). Maternal serum concentration of sCD30 was measured by a specific and sensitive enzyme-linked immunoassay. Non-parametric tests with post-hoc analysis were used for comparisons. A p value <0.05 was considered statistically significant. Results (1) The median sCD30 serum concentration of pregnant women was significantly higher than that of non-pregnant women (median: 29.7 U/mL, range: 12.2-313.2 vs. median: 23.2 U/mL, range: 14.6-195.1, respectively; p=0.01); (2) Patients with preeclampsia had a significantly lower median serum concentration of sCD30 than normal pregnant women (median: 24.7 U/mL, range: 7.6-71.2 vs. median: 29.7 U/mL, range: 12.2-313.2, respectively; p<0.05); (3) Mothers with SGA neonates had a lower median concentration of sCD30 than normal pregnant women (median: 23.4 U/mL, range: 7.1-105.3 vs. median: 29.7 U/mL, range: 12.2-313.2, respectively; p<0.05); and (4) There was no significant correlation (r=-0.059, p=0.5) between maternal serum sCD30 concentration and gestational age (19-38 weeks) in normal

Trends in Hospitalization and Mortality Rates Due to Acute Cardiovascular Disease in Castile and León, 2001 to 2015.

PubMed

López-Messa, Juan B; Andrés-de Llano, Jesús M; López-Fernández, Laura; García-Cruces, Jesús; García-Crespo, Julio; Prieto González, Miryam

2018-02-01

To analyze hospitalization and mortality rates due to acute cardiovascular disease (ACVD). We conducted a cross-sectional study of the hospital discharge database of Castile and León from 2001 to 2015, selecting patients with a principal discharge diagnosis of acute myocardial infarction (AMI), unstable angina, heart failure, or acute ischemic stroke (AIS). Trends in the rates of hospitalization/100 000 inhabitants/y and hospital mortality/1000 hospitalizations/y, overall and by sex, were studied by joinpoint regression analysis. A total of 239 586 ACVD cases (AMI 55 004; unstable angina 15 406; heart failure 111 647; AIS 57 529) were studied. The following statistically significant trends were observed: hospitalization: ACVD, upward from 2001 to 2007 (5.14; 95%CI, 3.5-6.8; P < .005), downward from 2011 to 2015 (3.7; 95%CI, 1.0-6.4; P < .05); unstable angina, downward from 2001 to 2010 (-12.73; 95%CI, -14.8 to -10.6; P < .05); AMI, upward from 2001 to 2003 (15.6; 95%CI, 3.8-28.9; P < .05), downward from 2003 to 2015 (-1.20; 95%CI, -1.8 to -0.6; P < .05); heart failure, upward from 2001 to 2007 (10.70; 95%CI, 8.7-12.8; P < .05), upward from 2007 to 2015 (1.10; 95%CI, 0.1-2.1; P < .05); AIS, upward from 2001 to 2007 (4.44; 95%CI, 2.9-6.0; P < .05). Mortality rates: downward from 2001 to 2015 in ACVD (-1.16; 95%CI, -2.1 to -0.2; P < .05), AMI (-3.37, 95%CI, -4.4 to -2, 3, P < .05), heart failure (-1.25; 95%CI, -2.3 to -0.1; P < .05) and AIS (-1.78; 95%CI, -2.9 to -0.6; P < .05); unstable angina, upward from 2001 to 2007 (24.73; 95%CI, 14.2-36.2; P < .05). The ACVD analyzed showed a rising trend in hospitalization rates from 2001 to 2015, which was especially marked for heart failure, and a decreasing trend in hospital mortality rates, which were similar in men and women. These data point to a stabilization and a decline in hospital mortality, attributable to established prevention measures. Copyright © 2017 Sociedad Española de Cardiología. Published by

Identification of the crossing point at N =21 between normal and intruder configurations

NASA Astrophysics Data System (ADS)

Licǎ, R.; Rotaru, F.; Borge, M. J. G.; Grévy, S.; NegoiÅ£ǎ, F.; Poves, A.; Sorlin, O.; Andreyev, A. N.; Borcea, R.; Costache, C.; De Witte, H.; Fraile, L. M.; Greenlees, P. T.; Huyse, M.; Ionescu, A.; Kisyov, S.; Konki, J.; Lazarus, I.; Madurga, M.; Mǎrginean, N.; Mǎrginean, R.; Mihai, C.; Mihai, R. E.; Negret, A.; Page, R. D.; Pakarinen, J.; Pascu, S.; Pucknell, V.; Rahkila, P.; Rapisarda, E.; Şerban, A.; Sotty, C. O.; Stan, L.; Stǎnoiu, M.; Tengblad, O.; Turturicǎ, A.; Van Duppen, P.; Wadsworth, R.; Warr, N.; IDS Collaboration

2017-02-01

The β- decay of 34Mg was used to study the 34Al nucleus through γ spectroscopy at the Isotope Separator On-Line facility of CERN. Previous studies identified two β -decaying states in 34Al having spin-parity assignments Jπ=4- dominated by the normal configuration π (d5/2) -1⊗ν (f7 /2) and Jπ=1+ by the intruder configuration π (d5/2) -1⊗ν (d3/2) -1(f7/2) 2 . Their unknown ordering and relative energy have been the subject of debate for the placement of 34Al inside or outside the N =20 "island of inversion." We report here that the 1+ intruder lies only 46.6 keV above the 4- ground state. In addition, a new half-life of T1 /2=44.9 (4 ) ms , that is twice as long as the previously measured 20(10) ms, has been determined for 34Mg. Large-scale shell-model calculations with the recently developed sdpf-u-mix interaction are compared with the new data and used to interpret the mechanisms at play at the very border of the N =20 island of inversion.

ETP-0492, Measured Residual Stresses in CYL S/N 53 Fretted Area

NASA Technical Reports Server (NTRS)

Webster, Ronald L.

1998-01-01

This test report presents the results of a residual stress survey of the inner clevis leg of lightweight cylinder SIN 053 as described by ETP-0492. The intent of this testing was to evaluate the residual stresses that occur in and around the inner clevis leg at the capture feature contact zone during a normal flight cycle. Lightweight case cylinder segment IU50717, S/N L053 from Flight STS-27 exhibited fretting around the contact zone of the inner clevis leg and the capture feature of the field joint. Post flight inspection revealed several large fitting pits on the inside of the inner clevis leg. This cylinder was assigned for both residual stress and metallurgical evaluation. This report is concerned only with the residual so= evaluations. The effects of glass bead cleaning and fi=ing were evaluated using the x-ray diffraction method.

77 FR 72408 - Amy S. Benjamin, N.P.; Decision and Order

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

... DEPARTMENT OF JUSTICE Drug Enforcement Administration Amy S. Benjamin, N.P.; Decision and Order On... Administration, issued an Order to Show Cause to Amy S. Benjamin, N.P. (Respondent), of Wheeler, Mississippi. The... CFR 0.100(b), I order that the Order to Show Cause issued to Amy S. Benjamin, N.P., be, and it hereby...

Chronological, geographical, and seasonal trends of human cases of avian influenza A (H5N1) in Vietnam, 2003-2014: a spatial analysis.

PubMed

Manabe, Toshie; Yamaoka, Kazue; Tango, Toshiro; Binh, Nguyen Gia; Co, Dao Xuan; Tuan, Nguyen Dang; Izumi, Shinyu; Takasaki, Jin; Chau, Ngo Quy; Kudo, Koichiro

2016-02-04

Human cases of highly pathogenic avian influenza A (H5N1) virus infection continue to occur in Southeast Asia. The objective of this study was to identify when and where human H5N1 cases have occurred in Vietnam and how the situation has changed from the beginning of the H5N1 outbreaks in 2003 through 2014, to assist with implementing methods of targeted disease management. We assessed the disease clustering and seasonal variation of human H5N1 cases in Vietnam to evaluate the geographical and monthly timing trends. The clustering of H5N1 cases and associated mortality were examined over three time periods: the outbreak period (2003-2005), the post-outbreak (2006-2009), and the recent period (2010-2014) using the flexibly shaped space-time scan statistic. The most likely cases to co-cluster and the elevated risks for incidence and mortality were assessed via calculation of the relative risk (RR). The H5N1 case seasonal variation was analysed as the cyclic trend in incidence data using Roger's statistical test. Between 2003 and 2005, H5N1 cases (RR: 2.15, p = 0.001) and mortality (RR: 2.49, p = 0.021) were significantly clustered in northern Vietnam. After 2010, H5N1 cases tended to occur on the border with Cambodia in the south, while H5N1 mortality clustered significantly in the Mekong delta area (RR: 6.62, p = 0.002). A significant seasonal variation was observed (p < 0.001), with a higher incidence of morbidity in December through April. These findings indicate that clinical preparedness for H5N1 in Vietnam needs to be strengthened in southern Vietnam in December-April.

Optical coherence tomography measurement of the retinal nerve fiber layer in normal and juvenile glaucomatous eyes.

PubMed

Mrugacz, Malgorzata; Bakunowicz-Lazarczyk, Alina

2005-01-01

The aim of this study was to quantitatively assess and compare the thickness of the retinal nerve fiber layer (RNFL) in normal and glaucomatous eyes of children using the optical coherence tomograph. The mean RNFL thickness of normal eyes (n=26) was compared with that of glaucomatous eyes (n=26). The eyes were classified into diagnostic groups based on conventional ophthalmological physical examination, Humphrey 30-2 visual fields, stereoscopic optic nerve head photography, and optical coherence tomography. The mean RNFL was significantly thinner in glaucomatous eyes than in normal eyes: 95+/-26.3 and 132+/-24.5 microm, respectively. More specifically, the RNFL was significantly thinner in glaucomatous eyes than in normal eyes in the inferior quadrant: 87+/-23.5 and 122+/-24.2 microm, respectively. The mean and inferior quadrant RFNL thicknesses as measured by the optical coherence tomograph showed a statistically significant correlation with glaucoma. Optical coherence tomography may contribute to tracking of juvenile glaucoma progression. Copyright (c) 2005 S. Karger AG, Basel.

Higher Education Trends (1997-1999): Program Evaluation. ERIC-HE Trends.

ERIC Educational Resources Information Center

Kezar, Adrianna J.

The amount of literature on program evaluation decreased in 1996, continuing a trend begun in the late 1980s. One exception to this is the literature on assessment. Another frequent issue is the technique of evaluation. Many examples of research on evaluation are from international settings, where accountability and evaluation appear to be…

Bulimia nervosa in overweight and normal-weight women.

PubMed

Masheb, Robin; White, Marney A

2012-02-01

The aim of the present study was to examine overweight bulimia nervosa (BN) in a community sample of women. Volunteers (n = 1964) completed self-report questionnaires of weight, binge eating, purging, and cognitive features. Participants were classified as overweight (body mass index ≥25) or normal weight (body mass index <25). Rates of BN within the overweight and normal-weight classes did not differ (6.4% vs 7.9%). Of the 131 participants identified as BN, 64% (n = 84) were classified as overweight BN and 36% (n = 47) as normal-weight BN. The overweight BN group had a greater proportion of ethnic minorities and reported significantly less restraint than the normal-weight BN group. Otherwise, the 2 groups reported similarly, even in terms of purging and depression. In summary, rates of BN did not differ between overweight and normal-weight women. Among BN participants, the majority (two thirds) were overweight. Differences in ethnicity and restraint, but little else, were found between overweight and normal-weight BN. Findings from the present study should serve to increase awareness of the weight range and ethnic diversity of BN, and highlight the need to address weight and cultural sensitivity in the identification and treatment of eating disorders. Copyright © 2012 Elsevier Inc. All rights reserved.

An Overview of U.S. Trends in Educational Software Design.

ERIC Educational Resources Information Center

Colvin, Linda B.

1989-01-01

Describes trends in educational software design in the United States for elementary and secondary education. Highlights include user-friendly software; learner control; interfacing the computer with other media, including television, telecommunications networks, and optical disk technology; microworlds; graphics; word processing; database…

Vacua and walls of mass-deformed Kähler nonlinear sigma models on S p (N )/U (N )

NASA Astrophysics Data System (ADS)

Arai, Masato; Golubtsova, Anastasia; Park, Chanyong; Shin, Sunyoung

2018-05-01

We study vacua and walls of mass-deformed Kähler nonlinear sigma models on S p (N )/U (N ). We identify elementary walls with the simple roots of U S p (2 N ) and discuss compressed walls, penetrable walls, and multiwalls by using the moduli matrix formalism.

Review of consumption trends and public policies promoting woody biomass as an energy feedstock in the U.S.

Treesearch

Francisco X. Aguilar; Nianfu Song; Stephen Shifley

2011-01-01

A review of the four main wood energy sectors in the U.S. was conducted to explore historic trends and the impact of alternative energy prices and public policies on wood energy consumption. High oil prices have triggered the adoption of government regulation and financial incentives to promote greater use of wood energy over the last four decades. However, the amount...

Minimal Conductance Quantization in a Normal-Metal/Unconventional-Superconductor Junction

NASA Astrophysics Data System (ADS)

Ikegaya, Satoshi; Asano, Yasuhiro

2018-04-01

We discuss the minimum value of the zero-bias differential conductance in a normal-metal/unconventional-superconductor junction. A numerical simulation demonstrates that the zero-bias conductance is quantized at (4e^2/h) N_ZES in the limit of strong impurity scatterings in the normal-metal. The integer N_ZES represents the number of perfect transmission channels through the junction. By focusing on the chiral symmetry of Hamiltonian, we prove the existence of N_ZES-fold degenerate resonant states in the dirty normal segment.

Epitaxial Growths of m-Plane AlGaN/GaN and AlInN/GaN Heterostructures Applicable for Normally-Off Mode High Power Field Effect Transistors on Freestanding GaN Substrates

DTIC Science & Technology

2011-08-17

cathodoluminescence (CL), and Hall effect measurement. We will disclose how structural and point defects affect the internal quantum efficiency. We have a complete...18. S. F. Chichibu, A. Uedono, T. Onuma, S. P. DenBaars, U. K. Mishra, J. S. Speck, and S. Nakamura, “Impact of Point Defects on the Luminescence...A. Uedono, “Major impacts of point defects and impurities on the carrier recombination dynamics in AlN,” Appl. Phys. Lett. 97(20), 201904 (2010

Long-term trends in stratospheric ozone, temperature, and water vapor over the Indian region

NASA Astrophysics Data System (ADS)

Thankamani Akhil Raj, Sivan; Venkat Ratnam, Madineni; Narayana Rao, Daggumati; Venkata Krishna Murthy, Boddam

2018-01-01

We have investigated the long-term trends in and variabilities of stratospheric ozone, water vapor and temperature over the Indian monsoon region using the long-term data constructed from multi-satellite (Upper Atmosphere Research Satellite (UARS MLS and HALOE, 1993-2005), Aura Microwave Limb Sounder (MLS, 2004-2015), Sounding of the Atmosphere using Broadband Emission Radiometry (SABER, 2002-2015) on board TIMED (Thermosphere Ionosphere Mesosphere Energetics Dynamics)) observations covering the period 1993-2015. We have selected two locations, namely, Trivandrum (8.4° N, 76.9° E) and New Delhi (28° N, 77° E), covering northern and southern parts of the Indian region. We also used observations from another station, Gadanki (13.5° N, 79.2° E), for comparison. A decreasing trend in ozone associated with NOx chemistry in the tropical middle stratosphere is found, and the trend turned to positive in the upper stratosphere. Temperature shows a cooling trend in the stratosphere, with a maximum around 37 km over Trivandrum (-1.71 ± 0.49 K decade-1) and New Delhi (-1.15 ± 0.55 K decade-1). The observed cooling trend in the stratosphere over Trivandrum and New Delhi is consistent with Gadanki lidar observations during 1998-2011. The water vapor shows a decreasing trend in the lower stratosphere and an increasing trend in the middle and upper stratosphere. A good correlation between N2O and O3 is found in the middle stratosphere (˜ 10 hPa) and poor correlation in the lower stratosphere. There is not much regional difference in the water vapor and temperature trends. However, upper stratospheric ozone trends over Trivandrum and New Delhi are different. The trend analysis carried out by varying the initial year has shown significant changes in the estimated trend.

Bis(O-ethyl dithio-carbonato-κS,S')bis-(pyridine-3-carbonitrile-κN)nickel(II).

PubMed

Kapoor, Sanjay; Kour, Ramandeep; Sachar, Renu; Kant, Rajni; Gupta, Vivek K; Kapoor, Kamini

2012-01-01

The Ni(2+) ion in the title complex, [Ni(C(3)H(5)OS(2))(2)(C(6)H(4)N(2))(2)], is in a strongly distorted octa-hedral coordination environment formed by an N(2)S(4) donor set, with the Ni(2+) ion located on a centre of inversion. In the crystal, weak C-H⋯S and C-H⋯N inter-actions are observed.

Essential Trends in Inorganic Chemistry (by D. M. P. Mingos)

NASA Astrophysics Data System (ADS)

Phillips, Reviewed By David A.

2000-05-01

The author has chosen to present his material in a distinctly different fashion from that of most inorganic chemistry textbook writers. Most texts are a mix of theory chapters and descriptive chapters, with the latter focusing on specific groups of elements. However, after a chapter laying out the quantum mechanical basis of the periodic table, Mingos has elected to organize the remaining chapters around vertical, horizontal, and diagonal relationships, or on isoelectronic and isostoichiometric relationships. I think this approach has worked remarkably well. Chapters 2-5 contain a wealth of information accompanied by clear, coherent discussions of the underlying principles that account for the observed trends and anomalies. Every serious inorganic chemist should have a copy of this text on his or her bookshelf. Chapter 1 is the least effective part of the book. Some of the quantum number notation is incorrect (m rather than ml , s rather than ms), some of the language is imprecise, and there are a few clear-cut errors. There is a nice discussion comparing the rmax of 2s and 2p vs 3s and 3p orbitals. However, most readers would be better served by the treatments in advanced inorganic texts such as those by Shriver or Huheey. Chapter 2 addresses vertical trends in the main-group elements. After discussing the influence of atomic size on atomic properties, Mingos describes and explains the second-row anomalies and the reversals in trends resulting from the addition of 3d and 4f subshells. He goes on to account for a variety of trends in the physical and chemical properties of main-group elements and their compounds. The chapter ends with tables summarizing a wide variety of properties, providing a wealth of information I have not seen presented in such a compact format anywhere else. Chapter 3 addresses the horizontal trends and diagonal relationships of the main-group elements. Among the highlights are discussions of the role of exchange energies in determining

Longitudinal trends in use of dietary supplements by U.S. Army personnel differ from those of civilians.

PubMed

Austin, Krista G; Price, Lori Lyn; McGraw, Susan M; McLellan, Tom M; Lieberman, Harris R

2016-12-01

Prevalence and patterns of dietary supplement (DS) use by U.S. Army soldiers differ from the civilian population. Longitudinal trends in use of DSs by civilians have been examined, but are unavailable in subpopulations such as military service members. The present study examined longitudinal changes in DS use by soldiers. A standardized questionnaire on DS use was administered in 2006-2007 (N = 989) and 2010-2011 (N = 1196) to convenience samples of active duty soldiers. Data were weighted for total population demographics of age, sex, and rank. Regular use of DSs by soldiers increased significantly (56% ± 1.6% vs. 64% ± 1.7%; p ≤ 0.001) over the 4 years primarily because of an increase of DS use among the youngest 18- to 24-year-old soldiers (43.0% ± 2.5% vs 62.3% ± 2.4%; p ≤ 0.01). Protein (22% ± 1.4% vs. 26% ± 1.5%; p ≤ 0.001) and combination (10.0% ± 1.0% vs. 24% ± 1.4%; p ≤ 0.001) product consumption also increased over the 4 years. Individual vitamin and mineral use - including iron, magnesium, selenium, and vitamins A, B 6 , B 12 , and D - significantly increased as well (p ≤ 0.05). In addition, expenditures on DSs by soldiers increased over time (p < 0.01). Reasons reported by soldiers for DS use suggest use increased to meet the occupational demands of military service. Educational interventions to minimize inappropriate use of DSs by soldiers are necessary to reduce adverse events resulting from unnecessary use of DSs and the financial burden associated with their use.

Long-term (10 year) trends in the chemistry of urban streams

NASA Astrophysics Data System (ADS)

Groffman, P. M.; Band, L. E.; Belt, K. T.; Kaushal, S.; Fisher, G. T.

2010-12-01

Weekly sampling of eight streams in the Baltimore metropolitan area has been carried out since 1998 as part of the NSF funded Baltimore urban Long-Term Ecological Research (BES LTER) project. The BES watersheds include 100% forested and agricultural catchments and developed watersheds ranging from very low-density (<1% impervious surface) suburban watersheds serviced by septic systems to more dense (> 40% impervious surface) urban watersheds. Stream discharge is continuously monitored at these sites by the U.S. Geological Survey (USGS). Stream samples are collected weekly regardless of flow conditions (no bias towards storm versus baseflow) and analyzed for nitrate, total nitrogen (N), phosphate, total phosphorus (P), chloride and sulfate. Ten-year analysis of the BES long-term study sites reveals several interesting spatial and temporal patterns. For N, the highest concentrations were found in the agricultural and suburban watersheds, followed by the urban sites, and finally by the forested site. Organic N was most important as a proportion of total N in the urban and forested sites. Spatial patterns in P were more complex, with urban, suburban and agricultural sites having the highest values. Over the ten year record, many sites showed significant changes in N concentrations, but few sites showed consistent patterns in P. The patterns in N were quite variable however, with some sites showing striking increases, while others showed striking decreases. Most (7 of 8) sites showed a decrease in the proportion of organic N, the trend was significant at 4 of the sites. There were few trends in the proportion of organic P. Discharge was a significant driver of variation in N and P export at some (mostly smaller watersheds) sites, for some solutes, but was not an overwhelmingly important driver of temporal variation. Key factors driving long-term patterns include climate variation and efforts to improve urban stream water quality by municipal authorities.

Aerosol Synthesis of N and N-S Doped and Crumpled Graphene Nanostructures.

PubMed

Carraro, Francesco; Cattelan, Mattia; Favaro, Marco; Calvillo, Laura

2018-06-06

Chemically modified graphene⁻based materials (CMG) are currently attracting a vast interest in their application in different fields. In particular, heteroatom-doped graphenes have revealed great potentialities in the field of electrocatalysis as substitutes of fuel cell noble metal⁻based catalysts. In this work, we investigate an innovative process for doping graphene nanostructures. We optimize a novel synthetic route based on aerosol preparation, which allows the simultaneous doping, crumpling, and reduction of graphene oxide (GO). Starting from aqueous solutions containing GO and the dopant precursors, we synthesize N- and N,S-dual-doped 3D graphene nanostructures (N-cGO and N,S-cGO). In the aerosol process, every aerosol droplet can be considered as a microreactor where dopant precursors undergo thermal decomposition and react with the GO flakes. Simultaneously, thanks to the relatively high temperature, GO undergoes crumpling and partial reduction. Using a combination of spectroscopic and microscopic characterization techniques, we investigate the morphology of the obtained materials and the chemical nature of the dopants within the crumpled graphene sheets. This study highlights the versatility of the aerosol process for the design of new CMG materials with tailored electrocatalytic properties.

Trends in stratospheric NO2

NASA Astrophysics Data System (ADS)

Gruzdev, A. N.

2009-04-01

Data of spectrometric ground-based measurements of stratospheric column NO2 contents at stations within the Network for the Detection of Atmospheric Composition Change (NDACC) are analyzed for linear trends. The trend analysis takes into account the NO2 seasonal variation, effects of the 11-year solar and geomagnetic activity cycles, effects of the quasi-biennial oscillation and the El Nino - Southern Oscillation, and the effects of the El Chichon and Pinatubo eruptions. The latitudinal distributions of the annual and seasonal trends in NO2 have been obtained. The annual trends are mostly positive in the southern hemisphere middle and low latitudes and negative in the European sector of the northern hemisphere middle latitudes. In the high and polar latitudes of the two hemispheres, the annual estimates of trends are mostly statistically insignificant. However, a positive NO2 trend is observed at 78°S in the Antarctic, while positive and negative trends are observed in the northern hemisphere high latitudes. The maximum positive and negative trends are about 10% per decade by module. Seasonal estimates of the trends differ generally from the annual estimates. At stations of Zvenigorod, Jungfraujoch (northern hemisphere middle latitudes), Lauder, and Macquarie Island (southern hemisphere middle latitudes) the signs of the NO2 trends do not depend on season, although the trend values vary with season. At other stations, trend values, their statistical significance, and even their signs can vary with season. Nitrogen oxides affects the photochemical balance of stratospheric ozone directly and indirectly, influencing the effectiveness of ozone destruction in the chlorine cycle. The observed significant trends in stratospheric NO2 should result in noticeable perturbations of the rates of ozone destruction in the nitrogen cycle. The sensitivities of photochemical balance of stratospheric ozone to long-term changes in stratospheric NO2 and chlorine are estimated using a

Episodic Rifting Events Within the Tjörnes Fracture Zone, an Onshore-Offshore Ridge-Transform in N-Iceland

NASA Astrophysics Data System (ADS)

Brandsdottir, B.; Magnusdottir, S.; Karson, J. A.; Detrick, R. S.; Driscoll, N. W.

2015-12-01

The multi-branched plate boundary across Iceland is made up of divergent and oblique rifts, and transform zones, characterized by entwined extensional and transform tectonics. The Tjörnes Fracture Zone (TFZ), located on the coast and offshore Northern Iceland, is a complex transform linking the northern rift zone (NVZ) on land with the Kolbeinsey Ridge offshore. Extension across TFZ is partitioned across three N-S trending rift basins; Eyjafjarðaráll, Skjálfandadjúp (SB) and Öxarfjörður and three WNW-NW oriented seismic lineaments; the Grímsey Oblique Rift, Húsavík-Flatey Faults (HFFs) and Dalvík Lineament. We compile the tectonic framework of the TFZ ridge-transform from aerial photos, satellite images, multibeam bathymetry and high-resolution seismic reflection data (Chirp). The rift basins are made up of normal faults with vertical displacements of up to 50-60 m, and post-glacial sediments of variable thickness. The SB comprises N5°W obliquely trending, eastward dipping normal faults as well as N10°E striking, westward dipping faults oriented roughly perpendicular to the N104°E spreading direction, indicative of early stages of rifting. Correlation of Chirp reflection data and tephrachronology from a sediment core within SB reveal major rifting episodes between 10-12.1 kyrs BP activating the whole basin, followed by smaller-scale fault movements throughout Holocene. Onshore faults have the same orientations as those mapped offshore and provide a basis for the interpretation of the kinematics of the faults throughout the region. These include transform parallel right-lateral, strike-slip faults separating domains dominated by spreading parallel left-lateral bookshelf faults. Shearing is most prominent along the HFFs, a system of right-lateral strike-slip faults with vertical displacement up to 15 m. Vertical fault movements reflect increased tectonic activity during early postglacial time coinciding with isostatic rebound enhancing volcanism within

Immunomodulatory activities of different solvent extracts from Tricholoma matsutake (S. Ito et S. Imai) singer (higher basidiomycetes) on normal mice.

PubMed

Yin, Xiulian; You, Qinghong; Jiang, Zhonghai

2012-01-01

The immunomodulatory activities of different solvent extracts from the culinary-medicinal mushroom Tricholoma matsutake were studied in vivo in normal mice. The extracts were prepared using different solvents in an order of increasing polarity. The immunomodulatory activities were investigated by measuring the thymus and spleen index, phagocytic rate of macrophage phagocytosis, delayed-type hypersensitivity, plaque-forming cell, and proliferation of splenocytes. Results demonstrated that water extract (WE) and n-butyl alcohol extract (BAE) of T. matsutake could enhance the immunity of mice significantly compared with the control group. Main components of WE and BAE were polysaccharides, proteins, and flavonoids; we presume that these may be the main immunomodulating and immuno-enhancing agents in T. matsutake.

Thermodynamic, Spectroscopic, and Computational Studies of f -Element Complexation by N -Hydroxyethyl-diethylenetriamine- N,N ', N ", N"-tetraacetic Acid

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grimes, Travis S.; Heathman, Colt R.; Jansone-Popova, Santa

Potentiometric and spectroscopic techniques were combined with DFT calculations to probe the coordination environment and determine thermodynamic features of trivalent f-element complexation by N-hydroxyethyl-diethylenetriamine-N,N',N",N"-tetraacetic acid, HEDTTA. Ligand protonation constants and lanthanide stability constants were determined using potentiometry. Five protonation constants were accessible in I = 2.0 M (H +/Na +)ClO 4. UV–vis spectroscopy was used to determine stability constants for Nd 3+ and Am 3+ complexation with HEDTTA. Luminescence spectroscopy indicates two water molecules in the inner coordination sphere of the Eu/HEDTTA complex, suggesting HEDTTA is heptadentate. Luminescence data was supported by DFT calculations, which demonstrate that substitution of themore » acetate pendant arm by a N-hydroxyethyl group weakens the metal–nitrogen bond. This bond elongation is reflected in HEDTTA’s ability to differentiate trivalent actinides from trivalent lanthanides. The trans-lanthanide Ln/HEDTTA complex stability trend is analogous to Ln/DTPA complexation; however, the loss of one chelate ring resulting from structural substitution weakens the complexation by ~3 orders of magnitude. Successful separation of trivalent americium from trivalent lanthanides was demonstrated when HEDTTA was utilized as aqueous holdback complexant in a liquid–liquid system. Time-dependent extraction studies for HEDTTA were compared to diethylenetriamine-N,N,N',N",N"-pentaacetic acid (DTPA) and N-hydroxyethyl-ethylenediamine-N,N',N'-triacetic acid (HEDTA). The results presented here indicate substantially enhanced phase-transfer kinetic rates for mixtures containing HEDTTA.« less

Thermodynamic, Spectroscopic, and Computational Studies of f -Element Complexation by N -Hydroxyethyl-diethylenetriamine- N,N ', N ", N"-tetraacetic Acid

DOE PAGES

Grimes, Travis S.; Heathman, Colt R.; Jansone-Popova, Santa; ...

2017-01-24

Potentiometric and spectroscopic techniques were combined with DFT calculations to probe the coordination environment and determine thermodynamic features of trivalent f-element complexation by N-hydroxyethyl-diethylenetriamine-N,N',N",N"-tetraacetic acid, HEDTTA. Ligand protonation constants and lanthanide stability constants were determined using potentiometry. Five protonation constants were accessible in I = 2.0 M (H +/Na +)ClO 4. UV–vis spectroscopy was used to determine stability constants for Nd 3+ and Am 3+ complexation with HEDTTA. Luminescence spectroscopy indicates two water molecules in the inner coordination sphere of the Eu/HEDTTA complex, suggesting HEDTTA is heptadentate. Luminescence data was supported by DFT calculations, which demonstrate that substitution of themore » acetate pendant arm by a N-hydroxyethyl group weakens the metal–nitrogen bond. This bond elongation is reflected in HEDTTA’s ability to differentiate trivalent actinides from trivalent lanthanides. The trans-lanthanide Ln/HEDTTA complex stability trend is analogous to Ln/DTPA complexation; however, the loss of one chelate ring resulting from structural substitution weakens the complexation by ~3 orders of magnitude. Successful separation of trivalent americium from trivalent lanthanides was demonstrated when HEDTTA was utilized as aqueous holdback complexant in a liquid–liquid system. Time-dependent extraction studies for HEDTTA were compared to diethylenetriamine-N,N,N',N",N"-pentaacetic acid (DTPA) and N-hydroxyethyl-ethylenediamine-N,N',N'-triacetic acid (HEDTA). The results presented here indicate substantially enhanced phase-transfer kinetic rates for mixtures containing HEDTTA.« less

Pre-existing normal faults have limited control on the rift geometry of the northern North Sea

NASA Astrophysics Data System (ADS)

Claringbould, Johan S.; Bell, Rebecca E.; Jackson, Christopher A.-L.; Gawthorpe, Robert L.; Odinsen, Tore

2017-10-01

Many rifts develop in response to multiphase extension with numerical and physical models suggesting that reactivation of first-phase normal faults and rift-related variations in bulk crustal rheology control the evolution and final geometry of subsequent rifts. However, many natural multiphase rifts are deeply buried and thus poorly exposed in the field and poorly imaged in seismic reflection data, making it difficult to test these models. Here we integrate recent 3D seismic reflection and borehole data across the entire East Shetland Basin, northern North Sea, to constrain the long-term, regional development of this multiphase rift. We document the following key stages of basin development: (i) pre-Triassic to earliest Triassic development of multiple sub-basins controlled by widely distributed, NNW- to NE-trending, east- and west-dipping faults; (ii) Triassic activity on a single major, NE-trending, west-dipping fault located near the basins western margin, and formation of a large half-graben; and (iii) Jurassic development of a large, E-dipping, N- to NE-trending half-graben near the eastern margin of the basin, which was associated with rift narrowing and strain focusing in the Viking Graben. In contrast to previous studies, which argue for two discrete periods of rifting during the Permian-Triassic and Late Jurassic-Early Cretaceous, we find that rifting in the East Shetland Basin was protracted from pre-Triassic to Cretaceous. We find that, during the Jurassic, most pre-Jurassic normal faults were buried and in some cases cross-cut by newly formed faults, with only a few being reactivated. Previously developed faults thus had only a limited control on the evolution and geometry of the later rift. We instead argue that strain migration and rift narrowing was linked to the evolving thermal state of the lithosphere, an interpretation supporting the predictions of lithosphere-scale numerical models. Our study indicates that additional regional studies of

FluBreaks: early epidemic detection from Google flu trends.

PubMed

Pervaiz, Fahad; Pervaiz, Mansoor; Abdur Rehman, Nabeel; Saif, Umar

2012-10-04

The Google Flu Trends service was launched in 2008 to track changes in the volume of online search queries related to flu-like symptoms. Over the last few years, the trend data produced by this service has shown a consistent relationship with the actual number of flu reports collected by the US Centers for Disease Control and Prevention (CDC), often identifying increases in flu cases weeks in advance of CDC records. However, contrary to popular belief, Google Flu Trends is not an early epidemic detection system. Instead, it is designed as a baseline indicator of the trend, or changes, in the number of disease cases. To evaluate whether these trends can be used as a basis for an early warning system for epidemics. We present the first detailed algorithmic analysis of how Google Flu Trends can be used as a basis for building a fully automated system for early warning of epidemics in advance of methods used by the CDC. Based on our work, we present a novel early epidemic detection system, called FluBreaks (dritte.org/flubreaks), based on Google Flu Trends data. We compared the accuracy and practicality of three types of algorithms: normal distribution algorithms, Poisson distribution algorithms, and negative binomial distribution algorithms. We explored the relative merits of these methods, and related our findings to changes in Internet penetration and population size for the regions in Google Flu Trends providing data. Across our performance metrics of percentage true-positives (RTP), percentage false-positives (RFP), percentage overlap (OT), and percentage early alarms (EA), Poisson- and negative binomial-based algorithms performed better in all except RFP. Poisson-based algorithms had average values of 99%, 28%, 71%, and 76% for RTP, RFP, OT, and EA, respectively, whereas negative binomial-based algorithms had average values of 97.8%, 17.8%, 60%, and 55% for RTP, RFP, OT, and EA, respectively. Moreover, the EA was also affected by the region's population size

Evaluation of trends in wheat yield models

NASA Technical Reports Server (NTRS)

Ferguson, M. C.

1982-01-01

Trend terms in models for wheat yield in the U.S. Great Plains for the years 1932 to 1976 are evaluated. The subset of meteorological variables yielding the largest adjusted R(2) is selected using the method of leaps and bounds. Latent root regression is used to eliminate multicollinearities, and generalized ridge regression is used to introduce bias to provide stability in the data matrix. The regression model used provides for two trends in each of two models: a dependent model in which the trend line is piece-wise continuous, and an independent model in which the trend line is discontinuous at the year of the slope change. It was found that the trend lines best describing the wheat yields consisted of combinations of increasing, decreasing, and constant trend: four combinations for the dependent model and seven for the independent model.

Analytic integrable systems: Analytic normalization and embedding flows

NASA Astrophysics Data System (ADS)

Zhang, Xiang

In this paper we mainly study the existence of analytic normalization and the normal form of finite dimensional complete analytic integrable dynamical systems. More details, we will prove that any complete analytic integrable diffeomorphism F(x)=Bx+f(x) in (Cn,0) with B having eigenvalues not modulus 1 and f(x)=O(|) is locally analytically conjugate to its normal form. Meanwhile, we also prove that any complete analytic integrable differential system x˙=Ax+f(x) in (Cn,0) with A having nonzero eigenvalues and f(x)=O(|) is locally analytically conjugate to its normal form. Furthermore we will prove that any complete analytic integrable diffeomorphism defined on an analytic manifold can be embedded in a complete analytic integrable flow. We note that parts of our results are the improvement of Moser's one in J. Moser, The analytic invariants of an area-preserving mapping near a hyperbolic fixed point, Comm. Pure Appl. Math. 9 (1956) 673-692 and of Poincaré's one in H. Poincaré, Sur l'intégration des équations différentielles du premier order et du premier degré, II, Rend. Circ. Mat. Palermo 11 (1897) 193-239. These results also improve the ones in Xiang Zhang, Analytic normalization of analytic integrable systems and the embedding flows, J. Differential Equations 244 (2008) 1080-1092 in the sense that the linear part of the systems can be nonhyperbolic, and the one in N.T. Zung, Convergence versus integrability in Poincaré-Dulac normal form, Math. Res. Lett. 9 (2002) 217-228 in the way that our paper presents the concrete expression of the normal form in a restricted case.

Trends in on-road vehicle emissions and ambient air quality in Atlanta, Georgia, USA, from the late 1990s through 2009.

PubMed

Vijayaraghavan, Krish; DenBleyker, Allison; Ma, Lan; Lindhjem, Chris; Yarwood, Greg

2014-07-01

On-road vehicle emissions of carbon monoxide (CO), nitrogen oxides (NO(x)), and volatile organic compounds (VOCs) during 1995-2009 in the Atlanta Metropolitan Statistical Area were estimated using the Motor Vehicle Emission Simulator (MOVES) model and data from the National Emissions Inventories and the State of Georgia. Statistically significant downward trends (computed using the nonparametric Theil-Sen method) in annual on-road CO, NO(x), and VOC emissions of 6.1%, 3.3%, and 6.0% per year, respectively, are noted during the 1995-2009 period despite an increase in total vehicle distance traveled. The CO and NO(x) emission trends are correlated with statistically significant downward trends in ambient air concentrations of CO and NO(x) in Atlanta ranging from 8.0% to 11.8% per year and from 5.8% to 8.7% per year, respectively, during similar time periods. Weather-adjusted summertime ozone concentrations in Atlanta exhibited a statistically significant declining trend of 2.3% per year during 2001-2009. Although this trend coexists with the declining trends in on-road NO(x), VOC, and CO emissions, identifying the cause of the downward trend in ozone is complicated by reductions in multiple precursors from different source sectors. Implications: Large reductions in on-road vehicle emissions of CO and NO(x) in Atlanta from the late 1990s to 2009, despite an increase in total vehicle distance traveled, contributed to a significant improvement in air quality through decreases in ambient air concentrations of CO and NO(x) during this time period. Emissions reductions in motor vehicles and other source sectors resulted in these improvements and the observed declining trend in ozone concentrations over the past decade. Although these historical trends cannot be extrapolated to the future because pollutant concentration contributions due to on-road vehicle emissions will likely become an increasingly smaller fraction of the atmospheric total, they provide an indication of

Pharmacokinetics and N-acetylation metabolism of S-methyl-l-cysteine and trans-S-1-propenyl-l-cysteine in rats and dogs.

PubMed

Amano, Hirotaka; Kazamori, Daichi; Itoh, Kenji

2016-11-01

1. Pharmacokinetics and N-acetylation metabolism of S-methyl-L-cysteine (SMC) and trans-S-1-propenyl-L-cysteine (S1PC) were examined in rats and dogs. SMC and S1PC (2-5 mg/kg) were well absorbed in both species with high bioavailability (88-100%). 2. SMC and S1PC were excreted only to a small extent in the urine of rats and dogs. The small renal clearance values (<0.03 l/h/kg) indicated the extensive renal reabsorption of SMC and S1PC, which potentially contributed to their long elimination half-lives (>5 h) in dogs. 3. S1PC, but not SMC, underwent N-acetylation extensively in vivo, which can be explained by the relative activities of N-acetylation of S1PC/SMC and deacetylation of their N-acetylated forms, N-acetyl-S1PC/N-acetyl-SMC, in the liver and kidney in vitro. The activities for S1PC N-acetylation were similar to or higher than those for N-acetyl-S1PC deacetylation in liver S9 fractions of rat and dog, whereas liver and kidney S9 fractions of rat and dog had little activity for SMC N-acetylation or considerably higher activities for N-acetyl-SMC deacetylation. 4. Our study demonstrated that the pharmacokinetics of SMC and S1PC in rats and dogs was characterized by high bioavailability and extensive renal reabsorption; however, the extent of undergoing the N-acetylation metabolism was extremely different between SMC and S1PC.

A second polymorph of catena-poly[[(1,10-phenanthroline-κ2 N,N′)copper(II)]-di-μ-thio­cyanato-κ2 N:S;κ2 S:N