Sample records for n750 polyox wsr

  1. Application of design of experiment for polyox and xanthan gum coated floating pulsatile delivery of sumatriptan succinate in migraine treatment.

    PubMed

    Jagdale, Swati C; Pawar, Chandrakala R

    2014-01-01

    Migraine follows circadian rhythm in which headache is more painful at the awakening time. This needs administration of dosage form at night time to release drug after lag period when pain gets worse. Sumatriptan succinate is a drug of choice for migraine. Sumatriptan succinate has bitter taste, low oral bioavailability, and shorter half-life. Present work deals with application of design of experiment for polyox and xanthan gum in development of press coated floating pulsatile tablet. Floating pulsatile concept was applied to increase gastric residence of the dosage form. Burst release was achieved through immediate release tablet using crospovidone as superdisintegrant (10%). Pulse lag time was achieved using swellable polymer polyox WSR 205 and xanthan gum. 3(2) experimental design was applied. Optimized formulation was evaluated for physical characteristics and in-vitro and in-vivo study. From results, it can be concluded that optimized batch F8 containing polyox WSR205 (72.72%) and xanthan gum (27.27%) of total weight of polymer has shown floating lag time of 55 ± 2 sec, drug content of 100.35 ± 0.4%, hardness of 6 ± 0.1 Kg/cm(2), and 98.69 ± 2% drug release in pulse manner with lag time of 7 ± 0.1 h. Optimized batch showed prolong gastric residence which was confirmed by in-vivo X-ray study.

  2. Application of Design of Experiment for Polyox and Xanthan Gum Coated Floating Pulsatile Delivery of Sumatriptan Succinate in Migraine Treatment

    PubMed Central

    Jagdale, Swati C.; Pawar, Chandrakala R.

    2014-01-01

    Migraine follows circadian rhythm in which headache is more painful at the awakening time. This needs administration of dosage form at night time to release drug after lag period when pain gets worse. Sumatriptan succinate is a drug of choice for migraine. Sumatriptan succinate has bitter taste, low oral bioavailability, and shorter half-life. Present work deals with application of design of experiment for polyox and xanthan gum in development of press coated floating pulsatile tablet. Floating pulsatile concept was applied to increase gastric residence of the dosage form. Burst release was achieved through immediate release tablet using crospovidone as superdisintegrant (10%). Pulse lag time was achieved using swellable polymer polyox WSR 205 and xanthan gum. 32 experimental design was applied. Optimized formulation was evaluated for physical characteristics and in-vitro and in-vivo study. From results, it can be concluded that optimized batch F8 containing polyox WSR205 (72.72%) and xanthan gum (27.27%) of total weight of polymer has shown floating lag time of 55 ± 2 sec, drug content of 100.35 ± 0.4%, hardness of 6 ± 0.1 Kg/cm2, and 98.69 ± 2% drug release in pulse manner with lag time of 7 ± 0.1 h. Optimized batch showed prolong gastric residence which was confirmed by in-vivo X-ray study. PMID:25530963

  3. Optimization studies on compression coated floating-pulsatile drug delivery of bisoprolol.

    PubMed

    Jagdale, Swati C; Bari, Nilesh A; Kuchekar, Bhanudas S; Chabukswar, Aniruddha R

    2013-01-01

    The purpose of the present work was to design and optimize compression coated floating pulsatile drug delivery systems of bisoprolol. Floating pulsatile concept was applied to increase the gastric residence of the dosage form having lag phase followed by a burst release. The prepared system consisted of two parts: a core tablet containing the active ingredient and an erodible outer shell with gas generating agent. The rapid release core tablet (RRCT) was prepared by using superdisintegrants with active ingredient. Press coating of optimized RRCT was done by polymer. A 3² full factorial design was used for optimization. The amount of Polyox WSR205 and Polyox WSR N12K was selected as independent variables. Lag period, drug release, and swelling index were selected as dependent variables. Floating pulsatile release formulation (FPRT) F13 at level 0 (55 mg) for Polyox WSR205 and level +1 (65 mg) for Polyox WSR N12K showed lag time of 4 h with >90% drug release. The data were statistically analyzed using ANOVA, and P < 0.05 was statistically significant. Release kinetics of the optimized formulation best fitted the zero order model. In vivo study confirms burst effect at 4 h in indicating the optimization of the dosage form.

  4. Optimization Studies on Compression Coated Floating-Pulsatile Drug Delivery of Bisoprolol

    PubMed Central

    Jagdale, Swati C.; Bari, Nilesh A.; Kuchekar, Bhanudas S.; Chabukswar, Aniruddha R.

    2013-01-01

    The purpose of the present work was to design and optimize compression coated floating pulsatile drug delivery systems of bisoprolol. Floating pulsatile concept was applied to increase the gastric residence of the dosage form having lag phase followed by a burst release. The prepared system consisted of two parts: a core tablet containing the active ingredient and an erodible outer shell with gas generating agent. The rapid release core tablet (RRCT) was prepared by using superdisintegrants with active ingredient. Press coating of optimized RRCT was done by polymer. A 32 full factorial design was used for optimization. The amount of Polyox WSR205 and Polyox WSR N12K was selected as independent variables. Lag period, drug release, and swelling index were selected as dependent variables. Floating pulsatile release formulation (FPRT) F13 at level 0 (55 mg) for Polyox WSR205 and level +1 (65 mg) for Polyox WSR N12K showed lag time of 4 h with >90% drug release. The data were statistically analyzed using ANOVA, and P < 0.05 was statistically significant. Release kinetics of the optimized formulation best fitted the zero order model. In vivo study confirms burst effect at 4 h in indicating the optimization of the dosage form. PMID:24367788

  5. A Study of the Drag Characteristics and Polymer Diffusion in the Boundary Layer of an Axisymmetric Body

    DTIC Science & Technology

    1976-03-12

    Reduction in Pipe Flow at R =14xl03 (from Hoyt (1972)) Guar Gum Karaya Polyox WSR 301 400 850 10 Polyacrylamide, Polyhall-250 20 21 ■.I...shown to be effec- tive drag reducers. Polysaccharides ( Guar ), polyethylene oxide, polyacrylamides, and sodium carboxymethyl...sifting the premeasured polyox powder onto the surface of the carefully weighed water which was being slowly stirred by a magnetic mixing bar. After a

  6. An Experimental Study of Polymer Drag Reduction and Boundary Layer Diffusion Characteristics for Incompressible Flow Over a Flat Plate.

    DTIC Science & Technology

    1979-08-15

    well industry with the use of the plant derivative, Guar Gum . Solutions of the product were used to suspend sand in the high-pressure, sand-water...Polymer Concentration (WPP.) Gum Karaya 850 Guar 400 Polyacrylamide, Polyhall-250 20 Polyox WSR-301 10 Hoyt and Fabula (1964) and Virk (1971) present data...achieved by Elata, Lehner, and Kahanovity (1966) for Guar Gum solutions and Meyer (1966) and Wells (1965) for Polyox. Many authors have described drag

  7. 25 CFR 162.547 - How must a WSR lease describe the land?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Wind and Solar Resource Leases Wsr Leases § 162.547 How must a WSR lease describe the land? (a) A WSR... description; (2) A survey-grade global positioning system description; or (3) Another description prepared by...

  8. 25 CFR 162.547 - How must a WSR lease describe the land?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Wind and Solar Resource Leases Wsr Leases § 162.547 How must a WSR lease describe the land? (a) A WSR... description; (2) A survey-grade global positioning system description; or (3) Another description prepared by...

  9. 25 CFR 162.548 - May a WSR lease allow compatible uses?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Wind and Solar Resource Leases Wsr Leases § 162.548 May a WSR lease allow compatible uses? The lease may provide for the Indian landowners to use, or authorize others to use, the leased premises for... 25 Indians 1 2014-04-01 2014-04-01 false May a WSR lease allow compatible uses? 162.548 Section...

  10. 25 CFR 162.548 - May a WSR lease allow compatible uses?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Wind and Solar Resource Leases Wsr Leases § 162.548 May a WSR lease allow compatible uses? The lease may provide for the Indian landowners to use, or authorize others to use, the leased premises for... 25 Indians 1 2013-04-01 2013-04-01 false May a WSR lease allow compatible uses? 162.548 Section...

  11. 25 CFR 162.574 - May a lessee assign a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May a lessee assign a WSR lease? 162.574 Section 162.574 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.574 May a lessee assign a WSR lease? (a) A lessee may...

  12. 25 CFR 162.567 - When will a WSR lease be effective?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false When will a WSR lease be effective? 162.567 Section 162.567 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.567 When will a WSR lease be effective? (a) A...

  13. 25 CFR 162.578 - May a lessee sublease a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May a lessee sublease a WSR lease? 162.578 Section 162.578 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.578 May a lessee sublease a WSR lease? (a) A...

  14. 25 CFR 162.570 - May the parties amend a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May the parties amend a WSR lease? 162.570 Section 162.570 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.570 May the parties amend a WSR lease? The...

  15. 25 CFR 162.578 - May a lessee sublease a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May a lessee sublease a WSR lease? 162.578 Section 162.578 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.578 May a lessee sublease a WSR lease? (a) A...

  16. 25 CFR 162.567 - When will a WSR lease be effective?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false When will a WSR lease be effective? 162.567 Section 162.567 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.567 When will a WSR lease be effective? (a) A...

  17. 25 CFR 162.568 - Must a WSR lease document be recorded?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Must a WSR lease document be recorded? 162.568 Section 162.568 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.568 Must a WSR lease document be recorded? (a...

  18. 25 CFR 162.574 - May a lessee assign a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May a lessee assign a WSR lease? 162.574 Section 162.574 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.574 May a lessee assign a WSR lease? (a) A lessee may...

  19. 25 CFR 162.570 - May the parties amend a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May the parties amend a WSR lease? 162.570 Section 162.570 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.570 May the parties amend a WSR lease? The...

  20. 25 CFR 162.568 - Must a WSR lease document be recorded?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Must a WSR lease document be recorded? 162.568 Section 162.568 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.568 Must a WSR lease document be recorded? (a...

  1. 25 CFR 162.582 - May a lessee mortgage a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May a lessee mortgage a WSR lease? 162.582 Section 162.582 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.582 May a lessee mortgage a WSR lease? (a...

  2. 25 CFR 162.582 - May a lessee mortgage a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May a lessee mortgage a WSR lease? 162.582 Section 162.582 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.582 May a lessee mortgage a WSR lease? (a...

  3. Report on the comparison of the scan strategies employed by the Patrick Air Force Base WSR-74C/McGill radar and the NWS Melbourne WSR-88D radar

    NASA Technical Reports Server (NTRS)

    Taylor, Gregory; Evans, Randolph; Manobianco, John; Schumann, Robin; Wheeler, Mark; Yersavich, Ann

    1994-01-01

    The objective of this investigation is to determine whether the current standard WSR-88D radar (NEXRAD) scan strategies permit the use of the Melbourne WSR-88D to perform the essential functions now performed by the Patrick Air Force Base (PAFB) WSR-74C/McGill radar for evaluating shuttle weather flight rules (FR) and launch commit criteria (LCC). To meet this objective, the investigation compared the beam coverage patterns of the WSR-74C/McGill radar located at PAFB and the WSR-88D radar located at the Melbourne National Weather Service (NWS) Office over the area of concern for weather FR and LCC evaluations. The analysis focused on beam coverage within four vertical 74 km radius cylinders (1 to 4 km above ground level (AGL), 4 to 8 km AGL, 8 to 12 km AGL, and 1 to 12 km AGL) centered on Kennedy Space Center (KSC) Launch Complex 39A. The PAFB WSR-74C/McGill radar is approximately 17 km north-northeast of the Melbourne WSR-88D radar. The beam coverage of the WSR-88D using VCP 11 located at the Melbourne NWS Office is comparable (difference in percent of the atmosphere sampled between the two radars is 10 percent or less) within the area of concern to the beam coverage of the WSR-74C/McGill radar located at PAFB. Both radars provide good beam coverage over much of the atmospheric region of concern. In addition, both radars provide poor beam coverage (coverage less than 50 percent) over limited regions near the radars due to the radars' cone of silence and gaps in coverage within the higher elevation scans. Based on scan strategy alone, the WSR-88D radar could be used to perform the essential functions now performed by the PAFB WSR-74C/McGill radar for evaluating shuttle weather FR and LCC. Other radar characteristics may, however, affect the decision as to which radar to use in a given case.

  4. 25 CFR 162.538 - What is the purpose of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... maintenance of wind and/or solar energy resource development projects. Activities include installing... Wind and Solar Resource Leases Wsr Leases § 162.538 What is the purpose of a WSR lease? A WSR lease... electricity and other related activities. Leases for biomass or waste-to-energy purposes are governed by...

  5. 25 CFR 162.538 - What is the purpose of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... maintenance of wind and/or solar energy resource development projects. Activities include installing... Wind and Solar Resource Leases Wsr Leases § 162.538 What is the purpose of a WSR lease? A WSR lease... electricity and other related activities. Leases for biomass or waste-to-energy purposes are governed by...

  6. National Weather Service Warning Performance Based on the WSR-88D.

    NASA Astrophysics Data System (ADS)

    Polger, Paul D.; Goldsmith, Barry S.; Przywarty, Richard C.; Bocchieri, Joseph R.

    1994-02-01

    The National Weather Service (NWS) began operational use of the Weather Surveillance Radar-1988 Doppler (WSR-88D) system in March 1991 at Norman, Oklahoma. WSR-88D data have been available to forecasters at five additional offices: Melbourne, Florida, and sterling, Virginia (since January 1992); St. Louis, Missouri, and Dodge City, Kansas (since March 1992); and Houston, Texas (since April 1992). The performance of the severe local storm and flash flood warning programs at the six offices before and after the availability of the WSR-88D was measured quantitatively. The verification procedures and statistical measures used in the quantitative evaluation were those used operationally by the NWS.The statistics show that the warnings improved dramatically when the WSR-88D was in operation. Specifically, the probability of detection of severe weather events increased and the number of false alarms decreased. There was also a marked improvement in the lead time for all severe local storm and flash flood events. These improvements were evident throughout the effective range of the radar. Stratification of severe local storm data by severe thunderstorms versus tornadoes revealed an improvement in the NWS's ability to differentiate between tornadic and nontornadic storms when the WSR-88D was in operation. Four individual cases are examined to illustrate how forecasters used the WSR-88D to achieve the improved results. These cases focus on the unique features of the WSR-88D that provide an advantage over conventional NWS radars.

  7. 25 CFR 162.540 - How long may the term of a WSR lease run?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How long may the term of a WSR lease run? 162.540 Section 162.540 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.540 How long may the term of a WSR lease run? (a) A WSR...

  8. 25 CFR 162.540 - How long may the term of a WSR lease run?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How long may the term of a WSR lease run? 162.540 Section 162.540 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.540 How long may the term of a WSR lease run? (a) A WSR...

  9. WSR-88D doppler radar detection of corn earworm moth migration.

    PubMed

    Westbrook, J K; Eyster, R S; Wolf, W W

    2014-07-01

    Corn earworm (Lepidoptera: Noctuidae) (CEW) populations infesting one crop production area may rapidly migrate and infest distant crop production areas. Although entomological radars have detected corn earworm moth migrations, the spatial extent of the radar coverage has been limited to a small horizontal view above crop production areas. The Weather Service Radar (version 88D) (WSR-88D) continuously monitors the radar-transmitted energy reflected by, and radial speed of, biota as well as by precipitation over areas that may encompass crop production areas. We analyzed data from the WSR-88D radar (S-band) at Brownsville, Texas, and related these data to aerial concentrations of CEW estimated by a scanning entomological radar (X-band) and wind velocity measurements from rawinsonde and pilot balloon ascents. The WSR-88D radar reflectivity was positively correlated (r2=0.21) with the aerial concentration of corn earworm-size insects measured by a scanning X-band radar. WSR-88D radar constant altitude plan position indicator estimates of wind velocity were positively correlated with wind speed (r2=0.56) and wind direction (r2=0.63) measured by pilot balloons and rawinsondes. The results reveal that WSR-88D radar measurements of insect concentration and displacement speed and direction can be used to estimate the migratory flux of corn earworms and other nocturnal insects, information that could benefit areawide pest management programs. In turn, identification of the effects of spatiotemporal patterns of migratory flights of corn earworm-size insects on WSR-88D radar measurements may lead to the development of algorithms that increase the accuracy of WSR-88D radar measurements of reflectivity and wind velocity for operational meteorology.

  10. WSR-88D doppler radar detection of corn earworm moth migration

    NASA Astrophysics Data System (ADS)

    Westbrook, J. K.; Eyster, R. S.; Wolf, W. W.

    2014-07-01

    Corn earworm (Lepidoptera: Noctuidae) (CEW) populations infesting one crop production area may rapidly migrate and infest distant crop production areas. Although entomological radars have detected corn earworm moth migrations, the spatial extent of the radar coverage has been limited to a small horizontal view above crop production areas. The Weather Service Radar (version 88D) (WSR-88D) continuously monitors the radar-transmitted energy reflected by, and radial speed of, biota as well as by precipitation over areas that may encompass crop production areas. We analyzed data from the WSR-88D radar (S-band) at Brownsville, Texas, and related these data to aerial concentrations of CEW estimated by a scanning entomological radar (X-band) and wind velocity measurements from rawinsonde and pilot balloon ascents. The WSR-88D radar reflectivity was positively correlated ( r 2 = 0.21) with the aerial concentration of corn earworm-size insects measured by a scanning X-band radar. WSR-88D radar constant altitude plan position indicator estimates of wind velocity were positively correlated with wind speed ( r 2 = 0.56) and wind direction ( r 2 = 0.63) measured by pilot balloons and rawinsondes. The results reveal that WSR-88D radar measurements of insect concentration and displacement speed and direction can be used to estimate the migratory flux of corn earworms and other nocturnal insects, information that could benefit areawide pest management programs. In turn, identification of the effects of spatiotemporal patterns of migratory flights of corn earworm-size insects on WSR-88D radar measurements may lead to the development of algorithms that increase the accuracy of WSR-88D radar measurements of reflectivity and wind velocity for operational meteorology.

  11. 25 CFR 162.565 - What is the approval process for a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.565 What is the approval process for a WSR... environmental laws, land use laws, and ordinances; (3) If the lease is being approved under 25 U.S.C. 415... other Federal or tribal land use requirements. (b) Upon receiving a WSR lease package, we will promptly...

  12. 25 CFR 162.565 - What is the approval process for a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.565 What is the approval process for a WSR... environmental laws, land use laws, and ordinances; (3) If the lease is being approved under 25 U.S.C. 415... other Federal or tribal land use requirements. (b) Upon receiving a WSR lease package, we will promptly...

  13. 25 CFR 162.544 - How must a WSR lease address ownership of permanent improvements?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How must a WSR lease address ownership of permanent improvements? 162.544 Section 162.544 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.544 How must a WSR lease...

  14. 25 CFR 162.544 - How must a WSR lease address ownership of permanent improvements?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How must a WSR lease address ownership of permanent improvements? 162.544 Section 162.544 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.544 How must a WSR lease...

  15. Introduction to the WSR-88D (NEXRAD) for ornithological research

    Treesearch

    Robert H. Diehl; Ronald P. Larkin

    2005-01-01

    The system of Doppler weather surveillance radars known as WSR-88D or more popularly as NEXRAD helped transform radar ornithology in the United States into a field that today attracts considerable attention from scientists and laypersons alike. As interest in ornithological applications of WSR-88D grows, so does the need to provide perspective on its use. In this paper...

  16. 25 CFR 162.542 - Are there mandatory provisions a WSR lease must contain?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.542 Are there mandatory provisions a...; purchasing, installing, operating, and maintaining WSR equipment; negotiating power purchase agreements; and...

  17. 25 CFR 162.542 - Are there mandatory provisions a WSR lease must contain?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.542 Are there mandatory provisions a...; purchasing, installing, operating, and maintaining WSR equipment; negotiating power purchase agreements; and...

  18. 25 CFR 162.502 - Who must obtain a WEEL or WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Wind and Solar Resource Leases General Provisions Applicable to Weels and Wsr Leases § 162.502 Who must... possession of the Indian land to conduct wind energy evaluation activities is authorized: (1) Under § 162.005.../or solar resources must obtain a WSR lease. (c) A tribe that conducts wind and solar resource...

  19. 25 CFR 162.502 - Who must obtain a WEEL or WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Wind and Solar Resource Leases General Provisions Applicable to Weels and Wsr Leases § 162.502 Who must... possession of the Indian land to conduct wind energy evaluation activities is authorized: (1) Under § 162.005.../or solar resources must obtain a WSR lease. (c) A tribe that conducts wind and solar resource...

  20. 25 CFR 162.589 - May BIA investigate compliance with a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May BIA investigate compliance with a WSR lease? 162.589 Section 162.589 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and Enforcement § 162.589 May...

  1. 25 CFR 162.589 - May BIA investigate compliance with a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May BIA investigate compliance with a WSR lease? 162.589 Section 162.589 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and Enforcement § 162.589 May...

  2. 25 CFR 162.503 - Is there a model WEEL or WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Is there a model WEEL or WSR lease? 162.503 Section 162.503 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases General Provisions Applicable to Weels and Wsr Leases § 162.503 Is there...

  3. 25 CFR 162.503 - Is there a model WEEL or WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Is there a model WEEL or WSR lease? 162.503 Section 162.503 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases General Provisions Applicable to Weels and Wsr Leases § 162.503 Is there...

  4. 25 CFR 162.543 - May permanent improvements be made under a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May permanent improvements be made under a WSR lease? 162.543 Section 162.543 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.543 May permanent improvements be made...

  5. 25 CFR 162.543 - May permanent improvements be made under a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May permanent improvements be made under a WSR lease? 162.543 Section 162.543 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.543 May permanent improvements be made...

  6. 25 CFR 162.562 - Must a lessee provide insurance for a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Must a lessee provide insurance for a WSR lease? 162.562 Section 162.562 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Bonding and Insurance § 162.562 Must a lessee provide...

  7. 25 CFR 162.562 - Must a lessee provide insurance for a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Must a lessee provide insurance for a WSR lease? 162.562 Section 162.562 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Bonding and Insurance § 162.562 Must a lessee provide...

  8. 25 CFR 162.553 - Must a WSR lease specify who receives monetary compensation payments?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Must a WSR lease specify who receives monetary compensation payments? 162.553 Section 162.553 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  9. 25 CFR 162.553 - Must a WSR lease specify who receives monetary compensation payments?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Must a WSR lease specify who receives monetary compensation payments? 162.553 Section 162.553 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  10. 25 CFR 162.557 - Must a WSR lease provide for compensation reviews or adjustments?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Must a WSR lease provide for compensation reviews or adjustments? 162.557 Section 162.557 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements...

  11. 25 CFR 162.552 - When are monetary compensation payments due under a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false When are monetary compensation payments due under a WSR lease? 162.552 Section 162.552 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements...

  12. 25 CFR 162.552 - When are monetary compensation payments due under a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false When are monetary compensation payments due under a WSR lease? 162.552 Section 162.552 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements...

  13. 25 CFR 162.557 - Must a WSR lease provide for compensation reviews or adjustments?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Must a WSR lease provide for compensation reviews or adjustments? 162.557 Section 162.557 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements...

  14. 25 CFR 162.594 - How will payment rights relating to WSR leases be allocated?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How will payment rights relating to WSR leases be allocated? 162.594 Section 162.594 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and...

  15. 25 CFR 162.594 - How will payment rights relating to WSR leases be allocated?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How will payment rights relating to WSR leases be allocated? 162.594 Section 162.594 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and...

  16. 25 CFR 162.595 - When will a cancellation of a WSR lease be effective?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false When will a cancellation of a WSR lease be effective? 162.595 Section 162.595 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and Enforcement § 162...

  17. 25 CFR 162.595 - When will a cancellation of a WSR lease be effective?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false When will a cancellation of a WSR lease be effective? 162.595 Section 162.595 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and Enforcement § 162...

  18. 25 CFR 162.545 - How will BIA enforce removal requirements in a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How will BIA enforce removal requirements in a WSR lease? 162.545 Section 162.545 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.545 How will BIA enforce removal...

  19. 25 CFR 162.545 - How will BIA enforce removal requirements in a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How will BIA enforce removal requirements in a WSR lease? 162.545 Section 162.545 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.545 How will BIA enforce removal...

  20. 25 CFR 162.566 - How will BIA decide whether to approve a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How will BIA decide whether to approve a WSR lease? 162.566 Section 162.566 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.566 How will BIA decide whether to...

  1. 25 CFR 162.566 - How will BIA decide whether to approve a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How will BIA decide whether to approve a WSR lease? 162.566 Section 162.566 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.566 How will BIA decide whether to...

  2. 25 CFR 162.560 - What forms of security are acceptable under a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What forms of security are acceptable under a WSR lease? 162.560 Section 162.560 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Bonding and Insurance § 162.560 What forms of...

  3. 25 CFR 162.560 - What forms of security are acceptable under a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What forms of security are acceptable under a WSR lease? 162.560 Section 162.560 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Bonding and Insurance § 162.560 What forms of...

  4. 25 CFR 162.551 - How will BIA determine fair market rental for a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements § 162.551 How will BIA determine fair market rental for a WSR lease? (a) We will use a market analysis... method; or (2) Use an approved market analysis, appraisal, or other appropriate valuation method from the...

  5. 25 CFR 162.551 - How will BIA determine fair market rental for a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements § 162.551 How will BIA determine fair market rental for a WSR lease? (a) We will use a market analysis... method; or (2) Use an approved market analysis, appraisal, or other appropriate valuation method from the...

  6. WSR-88D observations of volcanic ash

    USGS Publications Warehouse

    Wood, J.; Scott, C.; Schneider, D.

    2007-01-01

    Conclusions that may impact operations are summarized below: ??? Current VCPs may not be optimal for the scharacterization of volcanic events. Therefore, the development of a new VCP that combines the enhanced low level elevation density and increased temporal resolution of VCP 12 with the enhanced sensitivity of VCP 31. ??? Given currently available scan strategies, this preliminary investigation would suggest that it is advisable to use VCP 12 during the initial explosive phase of an eruptive event. Once the maximum reflectivity has dropped below 30 dBZ, VCP 31 should be used. ??? This study clearly indicates that WSR-88D Level II data offers many advantages over Level III data currently available in Alaska. The ability to access this data would open up greater opportunities for research. Given the proximity of WSR-88D platforms to active volcanoes in Alaska, as well as in the western Lower 48 states and Hawaii, radar data will likely play a major operational role when volcanic eruptions again pose a threat to life and property. The utilization of this tool to its maximum capability is vital.

  7. 25 CFR 162.591 - What will BIA do about a violation of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What will BIA do about a violation of a WSR lease? 162.591 Section 162.591 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and Enforcement § 162...

  8. 25 CFR 162.591 - What will BIA do about a violation of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What will BIA do about a violation of a WSR lease? 162.591 Section 162.591 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance, and Enforcement § 162...

  9. 25 CFR 162.554 - What form of monetary compensation payment is acceptable under a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What form of monetary compensation payment is acceptable under a WSR lease? 162.554 Section 162.554 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  10. 25 CFR 162.554 - What form of monetary compensation payment is acceptable under a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What form of monetary compensation payment is acceptable under a WSR lease? 162.554 Section 162.554 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  11. 25 CFR 162.597 - Will BIA appeal bond regulations apply to cancellation decisions involving WSR leases?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Will BIA appeal bond regulations apply to cancellation decisions involving WSR leases? 162.597 Section 162.597 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness...

  12. 25 CFR 162.597 - Will BIA appeal bond regulations apply to cancellation decisions involving WSR leases?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Will BIA appeal bond regulations apply to cancellation decisions involving WSR leases? 162.597 Section 162.597 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness...

  13. 25 CFR 162.575 - What are the consent requirements for an assignment of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What are the consent requirements for an assignment of a WSR lease? 162.575 Section 162.575 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.575 What are...

  14. 25 CFR 162.575 - What are the consent requirements for an assignment of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What are the consent requirements for an assignment of a WSR lease? 162.575 Section 162.575 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.575 What are...

  15. 25 CFR 162.579 - What are the consent requirements for a sublease of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What are the consent requirements for a sublease of a WSR lease? 162.579 Section 162.579 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.579 What are the...

  16. 25 CFR 162.580 - What is the approval process for a sublease of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What is the approval process for a sublease of a WSR lease? 162.580 Section 162.580 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.580 What is the...

  17. 25 CFR 162.572 - What is the approval process for an amendment to a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What is the approval process for an amendment to a WSR lease? 162.572 Section 162.572 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.572 What is the...

  18. 25 CFR 162.579 - What are the consent requirements for a sublease of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What are the consent requirements for a sublease of a WSR lease? 162.579 Section 162.579 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.579 What are the...

  19. 25 CFR 162.576 - What is the approval process for an assignment of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What is the approval process for an assignment of a WSR lease? 162.576 Section 162.576 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.576 What is the...

  20. 25 CFR 162.576 - What is the approval process for an assignment of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What is the approval process for an assignment of a WSR lease? 162.576 Section 162.576 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.576 What is the...

  1. 25 CFR 162.572 - What is the approval process for an amendment to a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What is the approval process for an amendment to a WSR lease? 162.572 Section 162.572 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.572 What is the...

  2. 25 CFR 162.580 - What is the approval process for a sublease of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What is the approval process for a sublease of a WSR lease? 162.580 Section 162.580 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.580 What is the...

  3. 25 CFR 162.555 - May a WSR lease provide for non-monetary or varying types of compensation?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May a WSR lease provide for non-monetary or varying types of compensation? 162.555 Section 162.555 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  4. 25 CFR 162.555 - May a WSR lease provide for non-monetary or varying types of compensation?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May a WSR lease provide for non-monetary or varying types of compensation? 162.555 Section 162.555 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  5. 25 CFR 162.584 - What is the approval process for a leasehold mortgage of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What is the approval process for a leasehold mortgage of a WSR lease? 162.584 Section 162.584 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.584 What...

  6. 25 CFR 162.584 - What is the approval process for a leasehold mortgage of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What is the approval process for a leasehold mortgage of a WSR lease? 162.584 Section 162.584 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.584 What...

  7. 25 CFR 162.583 - What are the consent requirements for a leasehold mortgage of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What are the consent requirements for a leasehold mortgage of a WSR lease? 162.583 Section 162.583 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.583...

  8. 25 CFR 162.583 - What are the consent requirements for a leasehold mortgage of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What are the consent requirements for a leasehold mortgage of a WSR lease? 162.583 Section 162.583 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.583...

  9. 25 CFR 162.573 - How will BIA decide whether to approve an amendment to a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How will BIA decide whether to approve an amendment to a WSR lease? 162.573 Section 162.573 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.573 How will...

  10. 25 CFR 162.577 - How will BIA decide whether to approve an assignment of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How will BIA decide whether to approve an assignment of a WSR lease? 162.577 Section 162.577 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.577 How will...

  11. 25 CFR 162.573 - How will BIA decide whether to approve an amendment to a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How will BIA decide whether to approve an amendment to a WSR lease? 162.573 Section 162.573 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.573 How will...

  12. 25 CFR 162.577 - How will BIA decide whether to approve an assignment of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How will BIA decide whether to approve an assignment of a WSR lease? 162.577 Section 162.577 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Assignments § 162.577 How will...

  13. 25 CFR 162.581 - How will BIA decide whether to approve a sublease of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How will BIA decide whether to approve a sublease of a WSR lease? 162.581 Section 162.581 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.581 How will BIA...

  14. 25 CFR 162.581 - How will BIA decide whether to approve a sublease of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How will BIA decide whether to approve a sublease of a WSR lease? 162.581 Section 162.581 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Subleases § 162.581 How will BIA...

  15. 25 CFR 162.556 - Will BIA notify a lessee when a payment is due under a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Will BIA notify a lessee when a payment is due under a WSR lease? 162.556 Section 162.556 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  16. 25 CFR 162.556 - Will BIA notify a lessee when a payment is due under a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Will BIA notify a lessee when a payment is due under a WSR lease? 162.556 Section 162.556 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation...

  17. 25 CFR 162.585 - How will BIA decide whether to approve a leasehold mortgage of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false How will BIA decide whether to approve a leasehold mortgage of a WSR lease? 162.585 Section 162.585 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.585...

  18. 25 CFR 162.585 - How will BIA decide whether to approve a leasehold mortgage of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false How will BIA decide whether to approve a leasehold mortgage of a WSR lease? 162.585 Section 162.585 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leasehold Mortgages § 162.585...

  19. Merged MMCR-WSR88D Reflectivities at SGP

    DOE Data Explorer

    Dong, Xiquan

    2008-03-05

    There are substantial attenuations of MMCR signals for very large LWP and during precipitation events. We have used the nearest precipitation radar (WSR-88D) to merge two measurements to better represent such selected cases. In the near future, we are going to provide all the cumulus cases from Jan. 1997 to present whenever the two datasets are available. The original 2 data sets:

  20. 25 CFR 162.598 - When will BIA issue a decision on an appeal from a WSR leasing decision?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false When will BIA issue a decision on an appeal from a WSR leasing decision? 162.598 Section 162.598 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR..., and Enforcement § 162.598 When will BIA issue a decision on an appeal from a WSR leasing decision? BIA...

  1. 25 CFR 162.598 - When will BIA issue a decision on an appeal from a WSR leasing decision?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false When will BIA issue a decision on an appeal from a WSR leasing decision? 162.598 Section 162.598 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR..., and Enforcement § 162.598 When will BIA issue a decision on an appeal from a WSR leasing decision? BIA...

  2. Sex Differences in Acute Ethanol Withdrawal Severity After Adrenalectomy and Gonadectomy in WSP and WSR Mice

    PubMed Central

    Strong, Moriah N.; Kaufman, Katherine R.; Crabbe, John C.; Finn, Deborah A.

    2009-01-01

    Recent findings suggest that the ability of ethanol (EtOH) to increase the levels of neurosteroids with potent γ-aminobutyric acid (GABA)ergic properties can influence measures of EtOH sensitivity. Earlier studies determined that removal of the adrenals and gonads diminished the steroidogenic effect of EtOH and significantly increased acute EtOH withdrawal severity in two inbred mouse strains that differed in withdrawal severity, suggesting the contribution of anticonvulsant GABAergic steroids to acute withdrawal in intact animals. Thus, the goal of the present studies was to investigate the consequence of steroid removal on acute EtOH withdrawal through excision of the adrenals and gonads, in another genetic animal model of EtOH withdrawal differences, the Withdrawal Seizure-Prone (WSP) and -Resistant (WSR) selected lines. Male and female WSP and WSR mice underwent surgical removal of the adrenals and gonads or no organ removal (SHAM). One to two weeks later, baseline handling-induced convulsions (HICs) were assessed, mice were given a 4 g/kg dose of ethanol, and HICs were measured hourly for 12 hours and then at 24 hours. The combination surgery significantly increased EtOH withdrawal in WSP and WSR female mice, as measured by area under the curve (AUC) and peak HIC scores. AUC was significantly positively correlated with plasma corticosterone levels and significantly negatively correlated with progesterone levels. In contrast, surgical status did not alter withdrawal severity in male WSP and WSR mice. Overall, the increase in acute ethanol withdrawal severity in female WSP and WSR mice following adrenalectomy and gonadectomy corroborate our recent evidence that withdrawal from a high dose of EtOH can be modulated by anticonvulsant steroids produced in the periphery. PMID:19671463

  3. 25 CFR 162.586 - When will an amendment, assignment, sublease, or leasehold mortgage of a WSR lease be effective?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false When will an amendment, assignment, sublease, or leasehold mortgage of a WSR lease be effective? 162.586 Section 162.586 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease...

  4. 25 CFR 162.586 - When will an amendment, assignment, sublease, or leasehold mortgage of a WSR lease be effective?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false When will an amendment, assignment, sublease, or leasehold mortgage of a WSR lease be effective? 162.586 Section 162.586 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease...

  5. 25 CFR 162.564 - Will BIA review a proposed WSR lease before or during preparation of the NEPA review documentation?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Will BIA review a proposed WSR lease before or during preparation of the NEPA review documentation? 162.564 Section 162.564 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease...

  6. 25 CFR 162.564 - Will BIA review a proposed WSR lease before or during preparation of the NEPA review documentation?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Will BIA review a proposed WSR lease before or during preparation of the NEPA review documentation? 162.564 Section 162.564 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease...

  7. WSR-88D doppler radar detection of corn earworm moth migration

    USDA-ARS?s Scientific Manuscript database

    Flying insects, birds, and bats contribute to radar reflectivity and radial velocity measured by Doppler weather radars. A study was conducted in the Lower Rio Grande Valley of Texas to determine the capability of Weather Service Radar (version 88D) (WSR-88D) to monitor migratory flights of corn ea...

  8. 25 CFR 162.569 - Will BIA require an appeal bond for an appeal of a decision on a WSR lease document?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Will BIA require an appeal bond for an appeal of a decision on a WSR lease document? 162.569 Section 162.569 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162...

  9. 25 CFR 162.561 - What is the release process for a performance bond or alternative form of security under a WSR...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What is the release process for a performance bond or alternative form of security under a WSR lease? 162.561 Section 162.561 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Bonding...

  10. 25 CFR 162.569 - Will BIA require an appeal bond for an appeal of a decision on a WSR lease document?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Will BIA require an appeal bond for an appeal of a decision on a WSR lease document? 162.569 Section 162.569 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162...

  11. 25 CFR 162.561 - What is the release process for a performance bond or alternative form of security under a WSR...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What is the release process for a performance bond or alternative form of security under a WSR lease? 162.561 Section 162.561 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Bonding...

  12. 25 CFR 162.592 - What will BIA do if a lessee does not cure a violation of a WSR lease on time?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What will BIA do if a lessee does not cure a violation of a WSR lease on time? 162.592 Section 162.592 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness...

  13. 25 CFR 162.592 - What will BIA do if a lessee does not cure a violation of a WSR lease on time?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What will BIA do if a lessee does not cure a violation of a WSR lease on time? 162.592 Section 162.592 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness...

  14. 25 CFR 162.546 - What requirements for due diligence must a WSR lease include?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.546 What requirements for due... lessee to: (1) Commence installation of energy facilities within 2 years after the effective date of the...

  15. 25 CFR 162.546 - What requirements for due diligence must a WSR lease include?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.546 What requirements for due... lessee to: (1) Commence installation of energy facilities within 2 years after the effective date of the...

  16. 25 CFR 162.539 - Must I obtain a WEEL before obtaining a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.539 Must I obtain a WEEL before obtaining... direct result of energy resource information gathered from a WEEL activity, obtaining a WEEL is not a...

  17. 25 CFR 162.539 - Must I obtain a WEEL before obtaining a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... AND PERMITS Wind and Solar Resource Leases Wsr Leases § 162.539 Must I obtain a WEEL before obtaining... direct result of energy resource information gathered from a WEEL activity, obtaining a WEEL is not a...

  18. Formulation and evaluation of floating tablet of H2-receptor antagonist.

    PubMed

    Kesarla, Rajesh S; Vora, Pratik Ashwinbhai; Sridhar, B K; Patel, Gunvant; Omri, Abdelwahab

    2015-01-01

    Conventional sustained dosage form of ranitidine hydrochloride (HCl) does not prevent frequent administration due to its degradation in colonic media and limited absorption in the upper part of GIT. Ranitidine HCl floating tablet was formulated with sublimation method to overcome the stated problem. Compatibility study for screening potential excipients was carried out using Fourier transform infrared spectroscopy (FT-IR) and differential scanning chromatography (DSC). Selected excipients were further evaluated for optimizing the formulation. Preliminary screening of binder, polymer and sublimating material was based on hardness and drug release, drug release with release kinetics and floating lag time with total floatation time, respectively. Selected excipients were subjected to 3(2) factorial design with polymer and sublimating material as independent factors. Matrix tablets were obtained by using 16/32" flat-faced beveled edges punches followed by sublimation. FT-IR and DSC indicated no significant incompatibility with selected excipients. Klucel-LF, POLYOX WSR N 60 K and l-menthol were selected as binder, polymer and sublimating material, respectively, for factorial design batches after preliminary screening. From the factorial design batches, optimum concentration to release the drug within 12 h was found to be 420 mg of POLYOX and 40 mg of l-menthol. Stability studies indicated the formulation as stable. Ranitidine HCl matrix floating tablets were formulated to release 90% of drug in stomach within 12 h. Hence, release of the drug could be sustained within narrow absorption site. Moreover, the dosage form was found to be floating within a fraction of second independent of the pH of media ensuring a robust formulation.

  19. 25 CFR 162.596 - What will BIA do if a lessee remains in possession after a WSR lease expires or is terminated or...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What will BIA do if a lessee remains in possession after a WSR lease expires or is terminated or cancelled? 162.596 Section 162.596 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr...

  20. 25 CFR 162.596 - What will BIA do if a lessee remains in possession after a WSR lease expires or is terminated or...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What will BIA do if a lessee remains in possession after a WSR lease expires or is terminated or cancelled? 162.596 Section 162.596 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr...

  1. Polyox and carrageenan based composite film dressing containing anti-microbial and anti-inflammatory drugs for effective wound healing.

    PubMed

    Boateng, Joshua S; Pawar, Harshavardhan V; Tetteh, John

    2013-01-30

    Polyethylene oxide (Polyox) and carrageenan based solvent cast films have been formulated as dressings for drug delivery to wounds. Films plasticised with glycerol were loaded with streptomycin (30%, w/w) and diclofenac (10%, w/w) for enhanced healing effects in chronic wounds. Blank and drug loaded films were characterised by texture analysis (for mechanical and mucoadhesive properties), scanning electron microscopy, differential scanning calorimetry, X-ray diffraction and Fourier transform infrared spectroscopy. In addition, swelling, in vitro drug release and antibacterial studies were conducted to further characterise the films. Both blank and drug loaded films showed a smooth, homogeneous surface morphology, excellent transparency, high elasticity and acceptable tensile (mechanical) properties. The drug loaded films showed a high capacity to absorb simulated wound fluid and significant mucoadhesion force which is expected to allow effective adherence to and protection of the wound. The films showed controlled release of both streptomycin and diclofenac for 72 h. These drug loaded films produced higher zones of inhibition against Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli compared to the individual drugs zones of inhibition. Incorporation of streptomycin can prevent and treat chronic wound infections whereas diclofenac can target the inflammatory phase of wound healing to relieve pain and swelling. Copyright © 2012 Elsevier B.V. All rights reserved.

  2. 25 CFR 162.571 - What are the consent requirements for an amendment to a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.571 What are... review. (d) Unless specifically authorized in the lease, a written power of attorney, or a court document...

  3. 25 CFR 162.571 - What are the consent requirements for an amendment to a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Amendments § 162.571 What are... review. (d) Unless specifically authorized in the lease, a written power of attorney, or a court document...

  4. 25 CFR 162.521 - May a lessee incorporate its WEEL analyses into its WSR lease analyses?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Weels § 162.521 May a lessee incorporate its WEEL analyses into its WSR lease analyses? Any analyses a lessee uses to bring a WEEL activity...

  5. 25 CFR 162.521 - May a lessee incorporate its WEEL analyses into its WSR lease analyses?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Weels § 162.521 May a lessee incorporate its WEEL analyses into its WSR lease analyses? Any analyses a lessee uses to bring a WEEL activity...

  6. 25 CFR 162.558 - What other types of payments are required under a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements... pay additional fees, taxes, and assessments associated with the use of the land, as determined by... another compatible use, such as grazing, the lessees may agree among themselves how to allocate payment of...

  7. 25 CFR 162.558 - What other types of payments are required under a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation Requirements... pay additional fees, taxes, and assessments associated with the use of the land, as determined by... another compatible use, such as grazing, the lessees may agree among themselves how to allocate payment of...

  8. 25 CFR 162.563 - What documents are required for BIA approval of a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.563 What documents are... authority that the proposed use is in conformance with applicable tribal law, if required by the tribe; (g... applicable Federal and tribal environmental and land use requirements, including any documentation prepared...

  9. 25 CFR 162.563 - What documents are required for BIA approval of a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Approval § 162.563 What documents are... authority that the proposed use is in conformance with applicable tribal law, if required by the tribe; (g... applicable Federal and tribal environmental and land use requirements, including any documentation prepared...

  10. 40 CFR 750.14 - Record.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Record. 750.14 Section 750.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT PROCEDURES... Manufacturing Exemptions § 750.14 Record. Section 750.3 shall be applicable with the exception that the words...

  11. 40 CFR 750.14 - Record.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Record. 750.14 Section 750.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT PROCEDURES... Manufacturing Exemptions § 750.14 Record. Section 750.3 shall be applicable with the exception that the words...

  12. 40 CFR 750.14 - Record.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Record. 750.14 Section 750.14 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT PROCEDURES... Manufacturing Exemptions § 750.14 Record. Section 750.3 shall be applicable with the exception that the words...

  13. 25 CFR 162.549 - How much monetary compensation must be paid under a WSR lease of tribal land?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation... tribe may request, in writing, that we determine fair market rental, in which case we will use a...

  14. 25 CFR 162.549 - How much monetary compensation must be paid under a WSR lease of tribal land?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Monetary Compensation... tribe may request, in writing, that we determine fair market rental, in which case we will use a...

  15. 40 CFR 750.20 - Cross-examination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Cross-examination. 750.20 Section 750.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... Manufacturing Exemptions § 750.20 Cross-examination. Section 750.8 shall be applicable. ...

  16. 23 CFR 750.152 - Application.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Application. 750.152 Section 750.152 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Directional and Official Signs § 750.152 Application. The following standards apply...

  17. 23 CFR 750.702 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Applicability. 750.702 Section 750.702 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising Control § 750.702 Applicability. The provisions of this subpart are applicable to all...

  18. 23 CFR 750.303 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Definitions. 750.303 Section 750.303 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.303 Definitions. (a) Sign...

  19. 23 CFR 750.308 - Reports.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Reports. 750.308 Section 750.308 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.308 Reports. Periodic...

  20. 50 CFR 600.750 - Definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 50 Wildlife and Fisheries 12 2014-10-01 2014-10-01 false Definitions. 600.750 Section 600.750..., DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Fishery Negotiation Panels § 600.750 Definitions... concurrence; or (2) agrees upon another specified definition. Fishery negotiation panel (FNP) means an...

  1. 50 CFR 600.750 - Definitions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 50 Wildlife and Fisheries 12 2012-10-01 2012-10-01 false Definitions. 600.750 Section 600.750..., DEPARTMENT OF COMMERCE MAGNUSON-STEVENS ACT PROVISIONS Fishery Negotiation Panels § 600.750 Definitions... concurrence; or (2) agrees upon another specified definition. Fishery negotiation panel (FNP) means an...

  2. 48 CFR 750.7101 - Authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Authority. 750.7101 Section 750.7101 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7101 Authority. Under section 633 of the Foreign Assistance Act of 1961...

  3. 25 CFR 162.550 - How much monetary compensation must be paid under a WSR lease of individually owned Indian land?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease... Indian landowners submit an economic analysis that is approved by the Office of Indian Energy & Economic...

  4. 23 CFR 750.308 - Reports.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Reports. 750.308 Section 750.308 Highways FEDERAL... Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.308 Reports. Periodic reports on site acquisitions and actual sign removals shall be submitted on FHWA Form 1424 and as...

  5. 23 CFR 750.308 - Reports.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Reports. 750.308 Section 750.308 Highways FEDERAL... Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.308 Reports. Periodic reports on site acquisitions and actual sign removals shall be submitted on FHWA Form 1424 and as...

  6. 25 CFR 162.593 - Will late payment charges or special fees apply to delinquent payments due under a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ..., DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease... fees to cover administrative costs incurred by the United States in the collection of the debt, if...

  7. 25 CFR 162.593 - Will late payment charges or special fees apply to delinquent payments due under a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease... fees to cover administrative costs incurred by the United States in the collection of the debt, if...

  8. 23 CFR 750.704 - Statutory requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Statutory requirements. 750.704 Section 750.704 Highways... BEAUTIFICATION Outdoor Advertising Control § 750.704 Statutory requirements. (a) 23 U.S.C. 131 provides that... Secretary in subpart B, part 750, chapter I, 23 CFR, National Standards for Directional and Official Signs...

  9. 23 CFR 750.303 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.303 Definitions. (a) Sign... 23 Highways 1 2010-04-01 2010-04-01 false Definitions. 750.303 Section 750.303 Highways FEDERAL..., billboard or other thing which is designed, intended of the advertising or informative contents of which is...

  10. 40 CFR 750.30 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Processing and Distribution in Commerce Exemptions § 750.30 Applicability. Sections 750.30-750.41 apply to all rulemakings under authority of section 6(e)(3)(B) of the Toxic Substances Control Act (TSCA), 15 U.S.C. 2605(e)(3)(B) with respect to petitions for PCB processing and distribution in commerce...

  11. 40 CFR 750.30 - Applicability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Processing and Distribution in Commerce Exemptions § 750.30 Applicability. Sections 750.30-750.41 apply to all rulemakings under authority of section 6(e)(3)(B) of the Toxic Substances Control Act (TSCA), 15 U.S.C. 2605(e)(3)(B) with respect to petitions for PCB processing and distribution in commerce...

  12. 40 CFR 750.30 - Applicability.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Processing and Distribution in Commerce Exemptions § 750.30 Applicability. Sections 750.30-750.41 apply to all rulemakings under authority of section 6(e)(3)(B) of the Toxic Substances Control Act (TSCA), 15 U.S.C. 2605(e)(3)(B) with respect to petitions for PCB processing and distribution in commerce...

  13. 40 CFR 750.30 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Processing and Distribution in Commerce Exemptions § 750.30 Applicability. Sections 750.30-750.41 apply to all rulemakings under authority of section 6(e)(3)(B) of the Toxic Substances Control Act (TSCA), 15 U.S.C. 2605(e)(3)(B) with respect to petitions for PCB processing and distribution in commerce...

  14. 40 CFR 750.34 - Record.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Record. 750.34 Section 750.34... Processing and Distribution in Commerce Exemptions § 750.34 Record. (a) No later than the date of proposal of a rule subject to this subpart, a rulemaking record for that rule will be established. It will...

  15. 40 CFR 750.34 - Record.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Record. 750.34 Section 750.34... Processing and Distribution in Commerce Exemptions § 750.34 Record. (a) No later than the date of proposal of a rule subject to this subpart, a rulemaking record for that rule will be established. It will...

  16. 40 CFR 750.34 - Record.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Record. 750.34 Section 750.34... Processing and Distribution in Commerce Exemptions § 750.34 Record. (a) No later than the date of proposal of a rule subject to this subpart, a rulemaking record for that rule will be established. It will...

  17. 23 CFR 750.151 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 750.151 Section 750.151 Highways FEDERAL... National Standards for Directional and Official Signs § 750.151 Purpose. (a) In section 131 of title 23 U.S... title 23 U.S.C. [38 FR 16044, June 30, 1973, as amended at 40 FR 21934, May 20, 1975] ...

  18. 40 CFR 750.3 - Record.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Record. 750.3 Section 750.3 Protection... Section 6 of the Toxic Substances Control Act § 750.3 Record. (a) No later than the date of proposal of a rule subject to this part, a rulemaking record for that rule shall be established. It shall consist of...

  19. 40 CFR 750.3 - Record.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Record. 750.3 Section 750.3 Protection... Section 6 of the Toxic Substances Control Act § 750.3 Record. (a) No later than the date of proposal of a rule subject to this part, a rulemaking record for that rule shall be established. It shall consist of...

  20. 40 CFR 750.3 - Record.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Record. 750.3 Section 750.3 Protection... Section 6 of the Toxic Substances Control Act § 750.3 Record. (a) No later than the date of proposal of a rule subject to this part, a rulemaking record for that rule shall be established. It shall consist of...

  1. 25 CFR 162.590 - May a WSR lease provide for negotiated remedies if there is a violation?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance... of a lease violation, including, but not limited to, the power to terminate the lease. If the lease provides one or both parties with the power to terminate the lease: (1) BIA approval of the termination is...

  2. 25 CFR 162.590 - May a WSR lease provide for negotiated remedies if there is a violation?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease Effectiveness, Compliance... of a lease violation, including, but not limited to, the power to terminate the lease. If the lease provides one or both parties with the power to terminate the lease: (1) BIA approval of the termination is...

  3. 23 CFR 750.302 - Policy.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Policy. 750.302 Section 750.302 Highways FEDERAL HIGHWAY..., displays, or devices which are lawfully existing under State law, in conformance with the terms of 23 U.S.C... relocation, pursuant to the provisions of 23 CFR § 750.305(a)(2), and which are required to be removed as a...

  4. 23 CFR 750.155 - State standards.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false State standards. 750.155 Section 750.155 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Directional and Official Signs § 750.155 State standards. This part does...

  5. 23 CFR 750.705 - Effective control.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 23 Highways 1 2013-04-01 2013-04-01 false Effective control. 750.705 Section 750.705 Highways... BEAUTIFICATION Outdoor Advertising Control § 750.705 Effective control. In order to provide effective control of... of applicable control requirements will apply; (h) Develop laws, regulations, and procedures to...

  6. 23 CFR 750.705 - Effective control.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Effective control. 750.705 Section 750.705 Highways... BEAUTIFICATION Outdoor Advertising Control § 750.705 Effective control. In order to provide effective control of... of applicable control requirements will apply; (h) Develop laws, regulations, and procedures to...

  7. 23 CFR 750.705 - Effective control.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Effective control. 750.705 Section 750.705 Highways... BEAUTIFICATION Outdoor Advertising Control § 750.705 Effective control. In order to provide effective control of... of applicable control requirements will apply; (h) Develop laws, regulations, and procedures to...

  8. 23 CFR 750.705 - Effective control.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 23 Highways 1 2014-04-01 2014-04-01 false Effective control. 750.705 Section 750.705 Highways... BEAUTIFICATION Outdoor Advertising Control § 750.705 Effective control. In order to provide effective control of... of applicable control requirements will apply; (h) Develop laws, regulations, and procedures to...

  9. 23 CFR 750.705 - Effective control.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Effective control. 750.705 Section 750.705 Highways... BEAUTIFICATION Outdoor Advertising Control § 750.705 Effective control. In order to provide effective control of... of applicable control requirements will apply; (h) Develop laws, regulations, and procedures to...

  10. 23 CFR 750.110 - State regulations.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false State regulations. 750.110 Section 750.110 Highways... BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent to the Interstate System Under the 1958 Bonus Program § 750.110 State regulations. A State may elect to prohibit signs...

  11. 23 CFR 750.110 - State regulations.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false State regulations. 750.110 Section 750.110 Highways... BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent to the Interstate System Under the 1958 Bonus Program § 750.110 State regulations. A State may elect to prohibit signs...

  12. 30 CFR 750.15 - Coal exploration.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Coal exploration. 750.15 Section 750.15 Mineral... PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.15 Coal exploration. Coal exploration operations on Indian lands shall be conducted in accordance with 25 CFR part 216...

  13. 30 CFR 750.15 - Coal exploration.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Coal exploration. 750.15 Section 750.15 Mineral... PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.15 Coal exploration. Coal exploration operations on Indian lands shall be conducted in accordance with 25 CFR part 216...

  14. 30 CFR 750.15 - Coal exploration.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Coal exploration. 750.15 Section 750.15 Mineral... PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.15 Coal exploration. Coal exploration operations on Indian lands shall be conducted in accordance with 25 CFR part 216...

  15. 30 CFR 750.15 - Coal exploration.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Coal exploration. 750.15 Section 750.15 Mineral... PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.15 Coal exploration. Coal exploration operations on Indian lands shall be conducted in accordance with 25 CFR part 216...

  16. 30 CFR 750.15 - Coal exploration.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Coal exploration. 750.15 Section 750.15 Mineral... PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.15 Coal exploration. Coal exploration operations on Indian lands shall be conducted in accordance with 25 CFR part 216...

  17. 32 CFR 750.36 - Time limitations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Time limitations. 750.36 Section 750.36 National... Tort Claims Act § 750.36 Time limitations. (a) Administrative claim. Every claim filed against the... the statutory time period, the day of the incident is excluded and the day the claim was presented...

  18. 32 CFR 750.36 - Time limitations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Time limitations. 750.36 Section 750.36 National... Tort Claims Act § 750.36 Time limitations. (a) Administrative claim. Every claim filed against the... the statutory time period, the day of the incident is excluded and the day the claim was presented...

  19. 32 CFR 750.36 - Time limitations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Time limitations. 750.36 Section 750.36 National... Tort Claims Act § 750.36 Time limitations. (a) Administrative claim. Every claim filed against the... the statutory time period, the day of the incident is excluded and the day the claim was presented...

  20. 32 CFR 750.36 - Time limitations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Time limitations. 750.36 Section 750.36 National... Tort Claims Act § 750.36 Time limitations. (a) Administrative claim. Every claim filed against the... the statutory time period, the day of the incident is excluded and the day the claim was presented...

  1. 40 CFR 750.40 - Cross-examination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Cross-examination. 750.40 Section 750... Processing and Distribution in Commerce Exemptions § 750.40 Cross-examination. (a) After the close of the... cross-examination. The request must be received by EPA within one week after a full transcript of the...

  2. 23 CFR 750.301 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 750.301 Section 750.301 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION... 23 U.S.C. 131(g). ...

  3. 40 CFR 750.34 - Record.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Processing and Distribution in Commerce Exemptions § 750.34 Record. (a) No later than the date of proposal of... consist of a separate identified filing space containing: (1) All documents required by § 750.31(d); (2...

  4. 23 CFR 750.710 - Landmark signs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Landmark signs. 750.710 Section 750.710 Highways FEDERAL... Outdoor Advertising Control § 750.710 Landmark signs. (a) 23 U.S.C. 131(c) permits the existence of signs... artistic significance, the preservation of which is consistent with the purpose of 23 U.S.C. 131. (b...

  5. 23 CFR 750.713 - Bonus provisions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Bonus provisions. 750.713 Section 750.713 Highways... BEAUTIFICATION Outdoor Advertising Control § 750.713 Bonus provisions. 23 U.S.C. 131(j) specifically provides... States are not exempt from the other provisions of 23 U.S.C. 131. If a State elects to comply with both...

  6. 40 CFR 750.8 - Cross-examination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Cross-examination. 750.8 Section 750.8... Section 6 of the Toxic Substances Control Act § 750.8 Cross-examination. (a) After the close of the... cross-examination. The request shall be received by EPA within one week after a full transcript of the...

  7. 48 CFR 750.7103 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Definitions. 750.7103 Section 750.7103 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  8. Development of a 750x750 pixels CMOS imager sensor for tracking applications

    NASA Astrophysics Data System (ADS)

    Larnaudie, Franck; Guardiola, Nicolas; Saint-Pé, Olivier; Vignon, Bruno; Tulet, Michel; Davancens, Robert; Magnan, Pierre; Corbière, Franck; Martin-Gonthier, Philippe; Estribeau, Magali

    2017-11-01

    Solid-state optical sensors are now commonly used in space applications (navigation cameras, astronomy imagers, tracking sensors...). Although the charge-coupled devices are still widely used, the CMOS image sensor (CIS), which performances are continuously improving, is a strong challenger for Guidance, Navigation and Control (GNC) systems. This paper describes a 750x750 pixels CMOS image sensor that has been specially designed and developed for star tracker and tracking sensor applications. Such detector, that is featuring smart architecture enabling very simple and powerful operations, is built using the AMIS 0.5μm CMOS technology. It contains 750x750 rectangular pixels with 20μm pitch. The geometry of the pixel sensitive zone is optimized for applications based on centroiding measurements. The main feature of this device is the on-chip control and timing function that makes the device operation easier by drastically reducing the number of clocks to be applied. This powerful function allows the user to operate the sensor with high flexibility: measurement of dark level from masked lines, direct access to the windows of interest… A temperature probe is also integrated within the CMOS chip allowing a very precise measurement through the video stream. A complete electro-optical characterization of the sensor has been performed. The major parameters have been evaluated: dark current and its uniformity, read-out noise, conversion gain, Fixed Pattern Noise, Photo Response Non Uniformity, quantum efficiency, Modulation Transfer Function, intra-pixel scanning. The characterization tests are detailed in the paper. Co60 and protons irradiation tests have been also carried out on the image sensor and the results are presented. The specific features of the 750x750 image sensor such as low power CMOS design (3.3V, power consumption<100mW), natural windowing (that allows efficient and robust tracking algorithms), simple proximity electronics (because of the on

  9. 50 CFR 600.750 - Definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 50 Wildlife and Fisheries 8 2010-10-01 2010-10-01 false Definitions. 600.750 Section 600.750 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION.... Consensus means unanimous concurrence among the members on a Fishery Negotiation Panel established under...

  10. 23 CFR 750.101 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 750.101 Section 750.101 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent to the Interstate System Under...

  11. 23 CFR 750.109 - Exclusions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Exclusions. 750.109 Section 750.109 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent to the Interstate System Under...

  12. 23 CFR 750.701 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 750.701 Section 750.701 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION... (FHWA) policies and requirements relating to the effective control of outdoor advertising under 23 U.S.C...

  13. 23 CFR 750.502 - Applicability.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Applicability. 750.502 Section 750.502 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION... to signs adjacent to the Interstate and primary systems which are required to be controlled under 23...

  14. 32 CFR 750.23 - Definitions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Definitions. 750.23 Section 750.23 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS Federal.... These entities operate from self-generated funds, rather than from funds appropriated by Congress...

  15. 25 CFR 162.550 - How much monetary compensation must be paid under a WSR lease of individually owned Indian land?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ..., DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease...) 100 percent of the landowners submit to us a written request to waive the valuation requirement; or (2... Indian landowners submit an economic analysis that is approved by the Office of Indian Energy & Economic...

  16. 23 CFR 750.152 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Application. 750.152 Section 750.152 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION... and sixty (660) feet of the right-of-way of such systems, outside of urban areas, visible from the...

  17. 25 CFR 162.522 - May a WEEL contain an option for the lessee to enter into a WSR lease?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false May a WEEL contain an option for the lessee to enter into a WSR lease? 162.522 Section 162.522 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Weels § 162.522 May a WEEL contain an...

  18. 25 CFR 162.522 - May a WEEL contain an option for the lessee to enter into a WSR lease?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false May a WEEL contain an option for the lessee to enter into a WSR lease? 162.522 Section 162.522 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Weels § 162.522 May a WEEL contain an...

  19. 48 CFR 750.000 - Scope of part.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Scope of part. 750.000 Section 750.000 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS 750.000 Scope of part. USAID is not among the agencies named in...

  20. 48 CFR 750.000 - Scope of part.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Scope of part. 750.000 Section 750.000 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS 750.000 Scope of part. USAID is not among the agencies named in...

  1. 48 CFR 750.000 - Scope of part.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Scope of part. 750.000 Section 750.000 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS 750.000 Scope of part. USAID is not among the agencies named in...

  2. 23 CFR 750.712 - Reclassification of signs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Reclassification of signs. 750.712 Section 750.712 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising Control § 750.712 Reclassification of signs. Any sign lawfully erected after...

  3. 40 CFR 272.702-272.750 - [Reserved

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 28 2012-07-01 2012-07-01 false [Reserved] 272.702-272.750 Section 272.702-272.750 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois §§ 272.702-272.750 [Reserved] ...

  4. 40 CFR 272.702-272.750 - [Reserved

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 27 2011-07-01 2011-07-01 false [Reserved] 272.702-272.750 Section 272.702-272.750 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois §§ 272.702-272.750 [Reserved] ...

  5. 40 CFR 272.702-272.750 - [Reserved

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 27 2014-07-01 2014-07-01 false [Reserved] 272.702-272.750 Section 272.702-272.750 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois §§ 272.702-272.750 [Reserved] ...

  6. 40 CFR 272.702-272.750 - [Reserved

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 28 2013-07-01 2013-07-01 false [Reserved] 272.702-272.750 Section 272.702-272.750 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois §§ 272.702-272.750 [Reserved] ...

  7. 48 CFR 750.7110-5 - Contract files.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

  8. 48 CFR 750.7110-5 - Contract files.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

  9. 48 CFR 750.7110-5 - Contract files.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

  10. 48 CFR 750.7110-5 - Contract files.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contract files. 750.7110-5 Section 750.7110-5 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... Interests of the United States 750.7110-5 Contract files. The fully executed action memorandum indicating...

  11. 40 CFR 272.702-272.750 - [Reserved

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false [Reserved] 272.702-272.750 Section 272.702-272.750 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) APPROVED STATE HAZARDOUS WASTE MANAGEMENT PROGRAMS Illinois §§ 272.702-272.750 [Reserved] ...

  12. 23 CFR 750.307 - FHWA project approval.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false FHWA project approval. 750.307 Section 750.307 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.307 FHWA project...

  13. 46 CFR 169.750 - Radio call sign.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 7 2010-10-01 2010-10-01 false Radio call sign. 169.750 Section 169.750 Shipping COAST... Control, Miscellaneous Systems, and Equipment Markings § 169.750 Radio call sign. Each vessel certificated for exposed or partially protected water service must have its radio call sign permanently displayed...

  14. 32 CFR 750.29 - Investigation and examination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Investigation and examination. 750.29 Section 750.29 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS Federal Tort Claims Act § 750.29 Investigation and examination. Subpart A of this part requires an...

  15. 23 CFR 750.501 - Purpose.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Purpose. 750.501 Section 750.501 Highways FEDERAL... pursuant to which a State may, if it desires, seek an exemption from the acquisition requirements of 23 U.S... removed. This exemption may be granted pursuant to the provisions of 23 U.S.C. 131(o). ...

  16. 23 CFR 750.503 - Exemptions.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Exemptions. 750.503 Section 750.503 Highways FEDERAL... (hereinafter called signs) within a defined area from being acquired under the provisions of 23 U.S.C. 131 upon... by 23 U.S.C. 131(o), the State shall establish: (1) Its requirements for the directional content of...

  17. 48 CFR 750.7105 - Approving authorities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Approving authorities. 750.7105 Section 750.7105 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...

  18. 48 CFR 750.7108 - Contractual requirements.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Contractual requirements. 750.7108 Section 750.7108 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...

  19. 32 CFR 750.25 - Scope of liability.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Scope of liability. 750.25 Section 750.25... Federal Tort Claims Act § 750.25 Scope of liability. (a) Territorial limitations. The FTCA does not apply... 46 U.S.C. 741-752 or 781-790. Claims under the Death on the High Seas Act (46 U.S.C. 761), however...

  20. 48 CFR 750.7106-3 - Mistakes.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Mistakes. 750.7106-3 Section 750.7106-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  1. 48 CFR 750.7110 - Processing cases.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Processing cases. 750.7110 Section 750.7110 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  2. 48 CFR 750.7106-1 - General.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false General. 750.7106-1 Section 750.7106-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  3. 48 CFR 750.7102 - General policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false General policy. 750.7102 Section 750.7102 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  4. Clinical implications of 750 mg, 5-day levofloxacin for the treatment of community-acquired pneumonia.

    PubMed

    File, Thomas M; Milkovich, Gary; Tennenberg, Alan M; Xiang, Jim X; Khashab, Mohammed M; Zadeikis, Neringa

    2004-09-01

    To evaluate the time to symptom resolution and i.v.-to-p.o. transition in community-acquired pneumonia (CAP) patients treated with 750 mg or 500 mg levofloxacin. A retrospective, subset analysis of a multicenter, randomized, double-blind, controlled trial comparing 750 mg levofloxacin for 5 days to 500 mg levofloxacin for 10 days for the treatment of CAP. A total of 528 CAP patients were included. Baseline symptoms were re-evaluated on Day 3 of therapy, and time to i.v.-to-p.o. transition was recorded for inpatients. For the overall population, 67.4% of patients receiving 750 mg levofloxacin had resolution of fever by Day 3 of therapy, compared to 54.6% of 500 mg treated patients (P = 0.006). Patients who started on 750 mg levofloxacin i.v. (N = 108) transitioned to p.o. in an average of 2.68 days while those starting on 500 mg i.v. (N = 124) transitioned in 2.95 days (P = 0.144). The median time for i.v.-to-p.o. switch was 2.35 days and 2.75 days for patients receiving 750 mg and 500 mg levofloxacin, respectively (P = 0.098, log rank test). By Day 3 of therapy, 68% of patients receiving the 750 mg dose had transitioned from i.v. to p.o. levofloxacin, compared with 61% of the 500 mg group (P = 0.280). The safety profiles were comparable for the two regimens. The 750 mg levofloxacin dose resulted in a greater proportion of patients with resolution of CAP symptoms by Day 3 when compared with 500 mg therapy. Consequently, the 750 mg regimen trended toward more rapid transition to p.o., potentially resulting in lower overall drug costs. Time to switch from i.v. to p.o. was determined by the investigators' discretion rather than a set protocol. Additionally, length of stay data was not collected in this study, which can significantly impact overall healthcare costs. Further research is required to fully understand the economic impact of the 750 mg, 5-day levofloxacin regimen.

  5. 49 CFR 236.750 - Interlocking, automatic.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Interlocking, automatic. 236.750 Section 236.750 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... manually, and which are so interconnected by means of electric circuits that their movements must succeed...

  6. PPC750 Performance Monitor

    NASA Technical Reports Server (NTRS)

    Meyer, Donald; Uchenik, Igor

    2007-01-01

    The PPC750 Performance Monitor (Perfmon) is a computer program that helps the user to assess the performance characteristics of application programs running under the Wind River VxWorks real-time operating system on a PPC750 computer. Perfmon generates a user-friendly interface and collects performance data by use of performance registers provided by the PPC750 architecture. It processes and presents run-time statistics on a per-task basis over a repeating time interval (typically, several seconds or minutes) specified by the user. When the Perfmon software module is loaded with the user s software modules, it is available for use through Perfmon commands, without any modification of the user s code and at negligible performance penalty. Per-task run-time performance data made available by Perfmon include percentage time, number of instructions executed per unit time, dispatch ratio, stack high water mark, and level-1 instruction and data cache miss rates. The performance data are written to a file specified by the user or to the serial port of the computer

  7. 23 CFR 750.110 - State regulations.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false State regulations. 750.110 Section 750.110 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent to the Interstate...

  8. Estimation of the surface stress near the eye wall of hurricanes using WSR-88D radar data

    NASA Astrophysics Data System (ADS)

    Businger, S.; Morrison, I.; Marks, F.; Dodge, P.; Businger, J. A.

    2003-04-01

    Analysis of Doppler velocity data from the WSR-88D radar during hurricane landfall reveals evidence of organized secondary circulations in the vicinity of the hurricane eye wall at low elevations. A Fourier analysis of the Velocity-Azimuthal Display (VAD) provides estimates of divergence (0th harmonic), wind speed and direction (1st harmonic), and deformation (2nd harmonic). A residual velocity field is obtained by subtracting the mean VAD velocity from the radial Doppler velocity for elevation angles between 0.5 and 5.5 degrees. The wavelength, length, depth, magnitude, and motion of velocity anomalies are then compiled from the residual velocity displays. The resulting statistics suggest the presence of organized secondary circulations or boundary layer (BL) rolls in the marine boundary layer of the hurricanes. To date, three storms have been examined: Fran (1996), Bonnie (1998), and Georges (1998) using WSR-88D data from Wilmington, N.C.; Morehead City, N.C.; and Key West, FL, respectively. The analysis focuses on the period between the time the first BL roll is identified and hurricane landfall. The number of BL rolls tracked in Bonnie, Fran, and Georges was 44, 56, and 24, respectively. BL rolls were less frequent in Georges, and the magnitude of the velocity anomalies was less than those in Fran and Bonnie. The average low-level (800 m--50 m) shear in Georges was substantially less than in the other storms, likely contributing to the fewer number of rolls identified and a lower intensity of the rolls. The wavelength of the observed BL rolls is about twice the horizontal distance between adjacent positive and negative velocity anomalies. Georges had the largest average wavelength (˜1400 m), followed by Fran (˜1320 m) and Bonnie (˜1200 m). The gradient between adjacent positive and negative anomalies corresponds to a horizontal wind shear of ˜14 m s-1 over 660 m, and a vertical shear component of vorticity of 2.0×10-2 s-1. Momentum fluxes associated with

  9. 30 CFR 750.10 - Information collection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Information collection. 750.10 Section 750.10 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN... Information collection. The Office of Management and Budget has determined that the information collection...

  10. 30 CFR 750.10 - Information collection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Information collection. 750.10 Section 750.10 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN... Information collection. The Office of Management and Budget has determined that the information collection...

  11. 32 CFR 750.43 - Claims payable.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Claims payable. 750.43 Section 750.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... of missiles and weapons, sonic booms, training and field exercises, and maneuvers that include...

  12. 30 CFR 750.10 - Information collection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Information collection. 750.10 Section 750.10 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN... Information collection. The Office of Management and Budget has determined that the information collection...

  13. 32 CFR 750.43 - Claims payable.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Claims payable. 750.43 Section 750.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... of missiles and weapons, sonic booms, training and field exercises, and maneuvers that include...

  14. 32 CFR 750.43 - Claims payable.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Claims payable. 750.43 Section 750.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... of missiles and weapons, sonic booms, training and field exercises, and maneuvers that include...

  15. 32 CFR 750.43 - Claims payable.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Claims payable. 750.43 Section 750.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... of missiles and weapons, sonic booms, training and field exercises, and maneuvers that include...

  16. 32 CFR 750.43 - Claims payable.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Claims payable. 750.43 Section 750.43 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... of missiles and weapons, sonic booms, training and field exercises, and maneuvers that include...

  17. The Effect of Polymer Additives on the Cavitation Threshold of Water

    DTIC Science & Technology

    1982-02-01

    AeSTRACT (Continue an reverse side it necesary and fdmflo bp WeekB nimwot) The effect of the polymer additives Polyox and Guar Gum on the acousticI...and different concentrations of Polyox and Guar Gum at variousI dissolved oxygen concentrations, using an ultrasonic technique. In this study, poor...of the polymer additives Polyox and Guar Gum on the acoustic cavitation threshold of water was studied as a function of polymer concentration and

  18. 32 CFR 750.6 - Claims: Presentment.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Claims: Presentment. 750.6 Section 750.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... Claims Act shall be submitted on DD Form 1842. 2 The claim and all other papers requiring the signature...

  19. 32 CFR 750.6 - Claims: Presentment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Claims: Presentment. 750.6 Section 750.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... Claims Act shall be submitted on DD Form 1842. 2 The claim and all other papers requiring the signature...

  20. 32 CFR 750.6 - Claims: Presentment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Claims: Presentment. 750.6 Section 750.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... Claims Act shall be submitted on DD Form 1842. 2 The claim and all other papers requiring the signature...

  1. 32 CFR 750.6 - Claims: Presentment.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Claims: Presentment. 750.6 Section 750.6 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS... Claims Act shall be submitted on DD Form 1842. 2 The claim and all other papers requiring the signature...

  2. 23 CFR 750.305 - Federal participation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Federal participation. 750.305 Section 750.305 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY... a period of time which makes them ineligible for compensation under 23 U.S.C. 131, or for rights in...

  3. 23 CFR 750.708 - Acceptance of state zoning.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Acceptance of state zoning. 750.708 Section 750.708 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising Control § 750.708 Acceptance of state zoning. (a) 23 U.S.C. 131(d) provide...

  4. 23 CFR 750.154 - Standards for directional signs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... may be erected along a single route approaching the activity; (iii) Signs located adjacent to the... 23 Highways 1 2011-04-01 2011-04-01 false Standards for directional signs. 750.154 Section 750.154... BEAUTIFICATION National Standards for Directional and Official Signs § 750.154 Standards for directional signs...

  5. 23 CFR 750.154 - Standards for directional signs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... may be erected along a single route approaching the activity; (iii) Signs located adjacent to the... 23 Highways 1 2010-04-01 2010-04-01 false Standards for directional signs. 750.154 Section 750.154... BEAUTIFICATION National Standards for Directional and Official Signs § 750.154 Standards for directional signs...

  6. 23 CFR 750.707 - Nonconforming signs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Nonconforming signs. 750.707 Section 750.707 Highways... 23 U.S.C. 131. These provisions also apply to nonconforming signs located in commercial and... compensation for the removal of nonconforming lawfully existing signs in accordance with the terms of 23 U.S.C...

  7. 30 CFR 750.16 - Performance standards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Performance standards. 750.16 Section 750.16... Performance standards. After OSM issues a permit under this part, a person conducting surface coal mining... shall adhere to the performance standards of 30 CFR chapter VII, subchapter B. [49 FR 38477, Sept. 28...

  8. 30 CFR 750.16 - Performance standards.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Performance standards. 750.16 Section 750.16... Performance standards. After OSM issues a permit under this part, a person conducting surface coal mining... shall adhere to the performance standards of 30 CFR chapter VII, subchapter B. [49 FR 38477, Sept. 28...

  9. 30 CFR 750.16 - Performance standards.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Performance standards. 750.16 Section 750.16... Performance standards. After OSM issues a permit under this part, a person conducting surface coal mining... shall adhere to the performance standards of 30 CFR chapter VII, subchapter B. [49 FR 38477, Sept. 28...

  10. 30 CFR 750.16 - Performance standards.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Performance standards. 750.16 Section 750.16... Performance standards. After OSM issues a permit under this part, a person conducting surface coal mining... shall adhere to the performance standards of 30 CFR chapter VII, subchapter B. [49 FR 38477, Sept. 28...

  11. 30 CFR 750.16 - Performance standards.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Performance standards. 750.16 Section 750.16... Performance standards. After OSM issues a permit under this part, a person conducting surface coal mining... shall adhere to the performance standards of 30 CFR chapter VII, subchapter B. [49 FR 38477, Sept. 28...

  12. 32 CFR 750.13 - Claims: Single service responsibility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Claims: Single service responsibility. 750.13 Section 750.13 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY CLAIMS GENERAL CLAIMS REGULATIONS General Provisions for Claims § 750.13 Claims: Single service responsibility. (a) The Department of Defense has assigned...

  13. The Impact of Heat Release in Turbine Film Cooling

    DTIC Science & Technology

    2008-06-01

    two torroidal half sections of cast zirconia- oxide ceramic, an Inconel ® jet ring, and a metal housing. A schematic of the WSR is shown in Figure...shielded from contact with the wall of the inserts by a ceramic tube, which was held in place by spot- welded shim stock. In Figure 28, one of the plenum...610 630 650 670 690 710 730 750 770 790 810 0 0.5 1 1.5 2 2.5 Te m p e ra tu re ( K ) Blowing Ratio Ts Block 1 Air Ts Block 1 N2 Ts Block 2

  14. 48 CFR 750.7100 - Scope of subpart.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Scope of subpart. 750.7100 Section 750.7100 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  15. 48 CFR 750.7100 - Scope of subpart.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Scope of subpart. 750.7100 Section 750.7100 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  16. 48 CFR 750.7100 - Scope of subpart.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Scope of subpart. 750.7100 Section 750.7100 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  17. 48 CFR 750.7104 - Types of actions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Types of actions. 750.7104 Section 750.7104 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy...

  18. 48 CFR 750.7109-1 - Filing requests.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Filing requests. 750.7109-1 Section 750.7109-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...

  19. 48 CFR 750.7106-4 - Informal commitments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Informal commitments. 750.7106-4 Section 750.7106-4 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...

  20. 48 CFR 750.7107 - Limitations upon exercise of authority.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Limitations upon exercise of authority. 750.7107 Section 750.7107 Federal Acquisition Regulations System AGENCY FOR... Actions To Protect Foreign Policy Interests of the United States 750.7107 Limitations upon exercise of...

  1. 48 CFR 750.7107 - Limitations upon exercise of authority.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Limitations upon exercise of authority. 750.7107 Section 750.7107 Federal Acquisition Regulations System AGENCY FOR... Actions To Protect Foreign Policy Interests of the United States 750.7107 Limitations upon exercise of...

  2. 48 CFR 750.7107 - Limitations upon exercise of authority.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Limitations upon exercise of authority. 750.7107 Section 750.7107 Federal Acquisition Regulations System AGENCY FOR... Actions To Protect Foreign Policy Interests of the United States 750.7107 Limitations upon exercise of...

  3. 48 CFR 750.7107 - Limitations upon exercise of authority.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Limitations upon exercise of authority. 750.7107 Section 750.7107 Federal Acquisition Regulations System AGENCY FOR... Actions To Protect Foreign Policy Interests of the United States 750.7107 Limitations upon exercise of...

  4. 48 CFR 750.7107 - Limitations upon exercise of authority.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Limitations upon exercise of authority. 750.7107 Section 750.7107 Federal Acquisition Regulations System AGENCY FOR... Actions To Protect Foreign Policy Interests of the United States 750.7107 Limitations upon exercise of...

  5. 23 CFR 750.103 - Measurements of distance.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Measurements of distance. 750.103 Section 750.103 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent to the Interstate...

  6. 30 CFR 750.13 - Small operator assistance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Small operator assistance. 750.13 Section 750.13 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN LANDS PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS...

  7. WSR-88D Cell Trends

    NASA Technical Reports Server (NTRS)

    Wheeler, Mark M.

    1998-01-01

    This report documents the Applied Meteorology Unit's evaluation of the Cell Trends display as a tool for radar operators to use in their evaluation of storm cell strength. The objective of the evaluation is to assess the utility of the WSR-88D graphical Cell Trends display for local radar cell interpretation in support of the 45th Weather Squadron (45 WS), Spaceflight Meteorology Group (SMG), and National Weather Service (NWS) Melbourne (MLB) operational requirements. The analysis procedure was to identify each cell and track the maximum reflectivity, height of maximum reflectivity, storm top, storm base, hail and severe hail probability, cell-based Vertically Integrated Liquid (VIL) and core aspect ratio using WATADS Build 9.0 cell trends information. One problem noted in the analysis phase was that the Storm Cell Identification and Tracking (SCIT) algorithm had a difficult time tracking the small cells associated with the Florida weather regimes. The analysis indicated numerous occasions when a cell track would end or an existing cell would be give a new ID in the middle of its life cycle. This investigation has found that most cells, which produce hail or microburst events, have discernable Cell Trends signatures. Forecasters should monitor the PUP's Cell Trends display for cells that show rapid (1 scan) changes in both the heights of maximum reflectivity and cell-based VIEL. It is important to note that this a very limited data set (four case days). Fifty-two storm cells were analyzed during those four days. The above mentioned t=ds, increase in the two cell attributes for hail events and decrease in the two cell attributes for wind events were noted in most of the cells. The probability of detection was 88% for both events. The False Alarm Rate (FAR) was a 36% for hail events and a respectable 25% for microburst events. In addition the Heidke Skill Score (HSS) is 0.65 for hail events and 0.67 for microburst events. For random forecast the HSS is 0 and that a

  8. 36 CFR 7.50 - Chickasaw Recreation Area.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 1 2013-07-01 2013-07-01 false Chickasaw Recreation Area. 7.50 Section 7.50 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR... around the Buckhorn Campground D Loop shoreline. (2) PWC may not be operated at greater than flat wake...

  9. 36 CFR 7.50 - Chickasaw Recreation Area.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 1 2011-07-01 2011-07-01 false Chickasaw Recreation Area. 7.50 Section 7.50 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR... around the Buckhorn Campground D Loop shoreline. (2) PWC may not be operated at greater than flat wake...

  10. 36 CFR 7.50 - Chickasaw Recreation Area.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 1 2012-07-01 2012-07-01 false Chickasaw Recreation Area. 7.50 Section 7.50 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR... around the Buckhorn Campground D Loop shoreline. (2) PWC may not be operated at greater than flat wake...

  11. 36 CFR 7.50 - Chickasaw Recreation Area.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Chickasaw Recreation Area. 7.50 Section 7.50 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR... around the Buckhorn Campground D Loop shoreline. (2) PWC may not be operated at greater than flat wake...

  12. 36 CFR 7.50 - Chickasaw Recreation Area.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 1 2014-07-01 2014-07-01 false Chickasaw Recreation Area. 7.50 Section 7.50 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR... around the Buckhorn Campground D Loop shoreline. (2) PWC may not be operated at greater than flat wake...

  13. 24 CFR 236.750 - Form of lease.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 24 Housing and Urban Development 2 2013-04-01 2013-04-01 false Form of lease. 236.750 Section 236... INSURANCE AND INTEREST REDUCTION PAYMENT FOR RENTAL PROJECTS Rental Assistance Payments § 236.750 Form of lease. (a) Lease form. Eligible tenants shall be required to execute a lease in a form approved by the...

  14. 24 CFR 236.750 - Form of lease.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 24 Housing and Urban Development 2 2012-04-01 2012-04-01 false Form of lease. 236.750 Section 236... INSURANCE AND INTEREST REDUCTION PAYMENT FOR RENTAL PROJECTS Rental Assistance Payments § 236.750 Form of lease. (a) Lease form. Eligible tenants shall be required to execute a lease in a form approved by the...

  15. 24 CFR 236.750 - Form of lease.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Form of lease. 236.750 Section 236... INSURANCE AND INTEREST REDUCTION PAYMENT FOR RENTAL PROJECTS Rental Assistance Payments § 236.750 Form of lease. (a) Lease form. Eligible tenants shall be required to execute a lease in a form approved by the...

  16. 24 CFR 236.750 - Form of lease.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 24 Housing and Urban Development 2 2014-04-01 2014-04-01 false Form of lease. 236.750 Section 236... INSURANCE AND INTEREST REDUCTION PAYMENT FOR RENTAL PROJECTS Rental Assistance Payments § 236.750 Form of lease. (a) Lease form. Eligible tenants shall be required to execute a lease in a form approved by the...

  17. 48 CFR 750.7106-2 - Amendments without consideration.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Amendments without consideration. 750.7106-2 Section 750.7106-2 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...

  18. 48 CFR 750.7106 - Standards for deciding cases.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Standards for deciding cases. 750.7106 Section 750.7106 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...

  19. 48 CFR 750.7109-3 - Facts and evidence.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Facts and evidence. 750.7109-3 Section 750.7109-3 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign...

  20. Advances in 750 nm VECSELs (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Saarinen, Esa J.; Ranta, Sanna; Lyytikäinen, Jari; Saarela, Antti; Sirbu, Alexei; Iakovlev, Vladimir; Kapon, Eli; Guina, Mircea

    2017-03-01

    Lasers operating in the transmission window of tissue at wavelengths between 700 and 800 nm are needed in numerous medical and biomedical applications, including photodynamic therapy and fluorescence microscopy. However, the performance of diode lasers in this spectral range is limited by the lack of appropriate compound semiconductors. Here, we review our recent research on 750 nm VECSELs. Two approaches to reaching the 750 nm wavelength will be discussed. The first approach relies on intra-cavity frequency doubling a wafer-fused 1500 nm VECSEL. The VECSEL gain chip comprises a GaAs-based DBR and an InP-based gain section, which allows for optical pumping with low-cost commercial diodes at 980 nm. With this scheme we have achieved watt-level output powers and tuning of the laser wavelength over a 40 nm band at around 750 nm. The second approach is direct emission at 750 nm using the AlGaAs/GaAs material system. In this approach visible wavelengths are required for optical pumping. However, the consequent higher costs compared to pumping at 980 nm are mitigated by the more compact laser setup and prospects of doubling the frequency to the ultraviolet range.

  1. 23 CFR 750.306 - Documentation for Federal participation.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Documentation for Federal participation. 750.306 Section 750.306 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners...

  2. 40 CFR 750.2 - Notice of proposed rulemaking.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 31 2014-07-01 2014-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...

  3. 40 CFR 750.2 - Notice of proposed rulemaking.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 32 2013-07-01 2013-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...

  4. 40 CFR 750.2 - Notice of proposed rulemaking.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 31 2011-07-01 2011-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...

  5. 40 CFR 750.2 - Notice of proposed rulemaking.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...

  6. 40 CFR 750.2 - Notice of proposed rulemaking.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., technological innovation, the environment, and public health. (v) Major impacts of alternatives to the proposed... 40 Protection of Environment 32 2012-07-01 2012-07-01 false Notice of proposed rulemaking. 750.2 Section 750.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES...

  7. 21 CFR 7.50 - Public notification of recall.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Public notification of recall. 7.50 Section 7.50 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ENFORCEMENT POLICY Recalls (Including Product Corrections)-Guidance on Policy, Procedures, and Industry...

  8. 33 CFR 207.750 - Puget Sound Area, Wash.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Section 207.750 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.750 Puget Sound Area, Wash. (a) Waterway connecting Port Townsend and... shall so be identified with the lockmaster. They shall be in compliance with Department of...

  9. 33 CFR 207.750 - Puget Sound Area, Wash.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Section 207.750 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.750 Puget Sound Area, Wash. (a) Waterway connecting Port Townsend and... shall so be identified with the lockmaster. They shall be in compliance with Department of...

  10. 33 CFR 207.750 - Puget Sound Area, Wash.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Section 207.750 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE NAVIGATION REGULATIONS § 207.750 Puget Sound Area, Wash. (a) Waterway connecting Port Townsend and... shall so be identified with the lockmaster. They shall be in compliance with Department of...

  11. A randomized controlled clinical trial of levofloxacin 750 mg versus 500 mg intravenous infusion in the treatment of community-acquired pneumonia.

    PubMed

    Zhao, Xu; Wu, Ju-Fang; Xiu, Qing-Yu; Wang, Chen; Zhang, De-Ping; Huang, Jian-An; Xie, Can-Mao; Sun, Sheng-Hua; Lv, Xiao-Ju; Si, Bin; Xiao, Zu-Ke; Zhang, Ying-Yuan

    2014-10-01

    The objective of this study was to compare the efficacy and safety of levofloxacin 750 mg for 5 days versus 500 mg for 7-14 days intravenous (IV) in the treatment of community-acquired pneumonia (CAP). This clinical trial was the first of its kind conducted in Chinese people and also in Asian population. A total of 241 were enrolled and randomized to 750 mg group (n = 121) or 500 mg (n = 120) group from 10 study centers. The median treatment duration was 5.0 days in 750 mg and 9.0 days in 500 mg group. The median total dose was 3750 mg in 750 mg and 4500 mg in 500 mg group. The bacterial eradication rate was 100% in both groups. The overall efficacy rate in 750 mg group was 86.2% (94/109), and 84.7% (94/111), in 500 mg group of full analysis set visit 4, 95% confidence interval of 1.6% (-7.8-10.9%); the statistical results showed that 750 mg group was non-inferior to 500 mg group. The most common clinical adverse drug reactions were injection site adverse reactions in both 750 mg group and 500 mg group; the other common adverse drug reactions were insomnia, nausea, skin rash, etc. The most common drug-related laboratory abnormalities were neutrophil percentage decreased, decreased white blood cell count, alanine aminotransferase, and aspartate aminotransferase elevation in both 750 mg group and 500 mg group. Most of adverse drug reactions were mild in severity and well-tolerated. In summary, the regimen of levofloxacin 750 mg IV for 5 days was at least as effective and well tolerated as 500 mg IV for 7-14 days for the treatment of CAP. Copyright © 2014. Published by Elsevier Inc.

  12. 40 CFR 63.750 - Test methods and procedures.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 11 2014-07-01 2014-07-01 false Test methods and procedures. 63.750...) National Emission Standards for Aerospace Manufacturing and Rework Facilities § 63.750 Test methods and... engineering reference texts, or other equivalent methods. (2) The composite vapor pressure of a blended hand...

  13. 32 CFR 750.49 - Delegations of adjudicating authority.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Delegations of adjudicating authority. 750.49... CLAIMS REGULATIONS Military Claims Act § 750.49 Delegations of adjudicating authority. (a) Settlement...)(3) of this section may delegate all or part of their settlement authority. Such delegation must be...

  14. 32 CFR 750.49 - Delegations of adjudicating authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Delegations of adjudicating authority. 750.49... CLAIMS REGULATIONS Military Claims Act § 750.49 Delegations of adjudicating authority. (a) Settlement...)(3) of this section may delegate all or part of their settlement authority. Such delegation must be...

  15. 40 CFR 63.750 - Test methods and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 10 2011-07-01 2011-07-01 false Test methods and procedures. 63.750...) National Emission Standards for Aerospace Manufacturing and Rework Facilities § 63.750 Test methods and... period as part of an ambient ozone control program. (1)(i) Determine the total organic HAP weight...

  16. 40 CFR 63.750 - Test methods and procedures.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 11 2013-07-01 2013-07-01 false Test methods and procedures. 63.750...) National Emission Standards for Aerospace Manufacturing and Rework Facilities § 63.750 Test methods and... period as part of an ambient ozone control program. (1)(i) Determine the total organic HAP weight...

  17. 40 CFR 63.750 - Test methods and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 11 2012-07-01 2012-07-01 false Test methods and procedures. 63.750...) National Emission Standards for Aerospace Manufacturing and Rework Facilities § 63.750 Test methods and... period as part of an ambient ozone control program. (1)(i) Determine the total organic HAP weight...

  18. 40 CFR 63.750 - Test methods and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 10 2010-07-01 2010-07-01 false Test methods and procedures. 63.750...) National Emission Standards for Aerospace Manufacturing and Rework Facilities § 63.750 Test methods and... period as part of an ambient ozone control program. (1)(i) Determine the total organic HAP weight...

  19. Interpreting 750 GeV diphoton excess in plain NMSSM

    DOE PAGES

    Badziak, Marcin; Olechowski, Marek; Pokorski, Stefan; ...

    2016-06-29

    NMSSM has enough ingredients to explain the diphoton excess at 750 GeV: singlet-like (pseudo) scalar (a) s and higgsinos as heavy vector-like fermions. We consider the production of the 750 GeV singlet-like pseudo scalar a from a decay of the doublet-like pseudo scalar A, and the subsequent decay of a into two photons via higgsino loop. We demonstrate that this cascade decay of the NMSSM Higgs bosons can explain the diphoton excess at 750 GeV.

  20. 23 CFR 750.154 - Standards for directional signs.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Standards for directional signs. 750.154 Section 750.154 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY... the State permits the erection of any such signs under section 131(c) of title 23 U.S.C., and this...

  1. 23 CFR 750.711 - Structures which have never displayed advertising material.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Structures which have never displayed advertising material. 750.711 Section 750.711 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising Control § 750.711 Structures...

  2. 23 CFR 750.304 - State policies and procedures.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false State policies and procedures. 750.304 Section 750.304... removal program under State law and complying with 23 U.S.C. 131 and its proposed time schedule for sign... severance damages pursuant to 23 CFR 710.304(h), and the law of the State before Federal participation will...

  3. 20 CFR 670.750 - Who may provide continued services for graduates?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Who may provide continued services for graduates? 670.750 Section 670.750 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF....750 Who may provide continued services for graduates? Placement agencies, centers or other agencies...

  4. 20 CFR 670.750 - Who may provide continued services for graduates?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Who may provide continued services for graduates? 670.750 Section 670.750 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF....750 Who may provide continued services for graduates? Placement agencies, centers or other agencies...

  5. 48 CFR 750.7109 - Submission of requests by contractors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Submission of requests by contractors. 750.7109 Section 750.7109 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...

  6. 20 CFR 670.750 - Who may provide continued services for graduates?

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Who may provide continued services for graduates? 670.750 Section 670.750 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Services § 670.750 Who may provide continued services for graduates? Placement agencies, centers or other...

  7. 20 CFR 670.750 - Who may provide continued services for graduates?

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Who may provide continued services for graduates? 670.750 Section 670.750 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Services § 670.750 Who may provide continued services for graduates? Placement agencies, centers or other...

  8. 20 CFR 670.750 - Who may provide continued services for graduates?

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Who may provide continued services for graduates? 670.750 Section 670.750 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... Services § 670.750 Who may provide continued services for graduates? Placement agencies, centers or other...

  9. The effect of prolonged exposure to 750 C air on the tribological performance of PM212

    NASA Technical Reports Server (NTRS)

    Bemis, Kirk; Bogdanski, Michael S.; Dellacorte, Christopher; Sliney, Harold E.

    1994-01-01

    The effect of prolonged exposure to 750 C air on the tribological performance and dimensional stability of PM212, a high temperature, self-lubricating composite, is studied. PM212, by weight, contains 70 percent metal-bonded Cr3C2, 15 percent BaF2/CaF2 eutectic, and 15 percent silver. Rub blocks were fabricated from PM212 by cold isostatic pressing followed by sintering. Prior to tribo-testing, the rub blocks were exposed to 750 C air for periods ranging from 100 to 1000 hours. Then, the rub blocks were slid against nickel-based superalloy disks in a double-rub-block tribometer in air under a 66 N load at temperatures from 25 to 750 C with a sliding velocity of 0.36 m/s. Unexposed rub blocks were tested for baseline comparison. Friction coefficients ranged from 0.24 to 0.37 for the unexposed rub blocks and from 0.32 to 0.56 for the exposed ones. Wear for both the composite blocks and superalloy disks was typically in the moderate to low range of 10(exp -5) to 10(exp -6) mm(exp 3)/N-m. Friction and wear data were similar for the rub blocks exposed for 100, 500, and 1000 hours. Prolonged exposure to 750 C air increased friction and wear of the PM212 rub blocks at room temperature, but their triboperformance remained unaffected at higher temperatures, probably due to the formation of lubricious metal oxides. Dimensional stability of the composite was studied by exposing specimens of varying thicknesses for 500 hours in air at 750 C. Block thicknesses were found to increase with increased exposure time until steady state was reached after 100 hours of exposure, probably due to oxidation.

  10. 42 CFR 403.750 - Estimate of expenditures and adjustments.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 2 2011-10-01 2011-10-01 false Estimate of expenditures and adjustments. 403.750 Section 403.750 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS SPECIAL PROGRAMS AND PROJECTS Religious Nonmedical Health Care Institutions...

  11. 42 CFR 403.750 - Estimate of expenditures and adjustments.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 2 2014-10-01 2014-10-01 false Estimate of expenditures and adjustments. 403.750 Section 403.750 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS SPECIAL PROGRAMS AND PROJECTS Religious Nonmedical Health Care Institutions...

  12. 42 CFR 403.750 - Estimate of expenditures and adjustments.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Estimate of expenditures and adjustments. 403.750 Section 403.750 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS SPECIAL PROGRAMS AND PROJECTS Religious Nonmedical Health Care Institutions...

  13. 42 CFR 403.750 - Estimate of expenditures and adjustments.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 42 Public Health 2 2012-10-01 2012-10-01 false Estimate of expenditures and adjustments. 403.750 Section 403.750 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS SPECIAL PROGRAMS AND PROJECTS Religious Nonmedical Health Care Institutions...

  14. 42 CFR 403.750 - Estimate of expenditures and adjustments.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 2 2013-10-01 2013-10-01 false Estimate of expenditures and adjustments. 403.750 Section 403.750 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL PROVISIONS SPECIAL PROGRAMS AND PROJECTS Religious Nonmedical Health Care Institutions...

  15. 30 CFR 750.1 - Scope.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.1 Scope. This subchapter provides for the regulation of surface coal mining and reclamation operations on Indian lands and constitutes the Federal program for Indian lands. ...

  16. 30 CFR 750.1 - Scope.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.1 Scope. This subchapter provides for the regulation of surface coal mining and reclamation operations on Indian lands and constitutes the Federal program for Indian lands. ...

  17. 30 CFR 750.1 - Scope.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.1 Scope. This subchapter provides for the regulation of surface coal mining and reclamation operations on Indian lands and constitutes the Federal program for Indian lands. ...

  18. 30 CFR 750.1 - Scope.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.1 Scope. This subchapter provides for the regulation of surface coal mining and reclamation operations on Indian lands and constitutes the Federal program for Indian lands. ...

  19. 30 CFR 750.1 - Scope.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.1 Scope. This subchapter provides for the regulation of surface coal mining and reclamation operations on Indian lands and constitutes the Federal program for Indian lands. ...

  20. 20 CFR 404.750 - Evidence of a parent's support.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Evidence of a parent's support. 404.750 Section 404.750 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL OLD-AGE, SURVIVORS AND... parent's support. If you apply for parent's benefits, we will ask you for evidence to show that you...

  1. 32 CFR 750.7 - Claims: Action by receiving command.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Claims: Action by receiving command. 750.7... CLAIMS REGULATIONS General Provisions for Claims § 750.7 Claims: Action by receiving command. (a) Record date of receipt. The first command receiving a claim shall stamp or mark the date of receipt on the...

  2. 32 CFR 750.7 - Claims: Action by receiving command.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Claims: Action by receiving command. 750.7... CLAIMS REGULATIONS General Provisions for Claims § 750.7 Claims: Action by receiving command. (a) Record date of receipt. The first command receiving a claim shall stamp or mark the date of receipt on the...

  3. 32 CFR 750.7 - Claims: Action by receiving command.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Claims: Action by receiving command. 750.7... CLAIMS REGULATIONS General Provisions for Claims § 750.7 Claims: Action by receiving command. (a) Record date of receipt. The first command receiving a claim shall stamp or mark the date of receipt on the...

  4. 32 CFR 750.7 - Claims: Action by receiving command.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Claims: Action by receiving command. 750.7... CLAIMS REGULATIONS General Provisions for Claims § 750.7 Claims: Action by receiving command. (a) Record date of receipt. The first command receiving a claim shall stamp or mark the date of receipt on the...

  5. 32 CFR 750.7 - Claims: Action by receiving command.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Claims: Action by receiving command. 750.7... CLAIMS REGULATIONS General Provisions for Claims § 750.7 Claims: Action by receiving command. (a) Record date of receipt. The first command receiving a claim shall stamp or mark the date of receipt on the...

  6. 20 CFR 404.750 - Evidence of a parent's support.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... DISABILITY INSURANCE (1950- ) Evidence Evidence for Child's and Parent's Benefits § 404.750 Evidence of a parent's support. If you apply for parent's benefits, we will ask you for evidence to show that you... 20 Employees' Benefits 2 2011-04-01 2011-04-01 false Evidence of a parent's support. 404.750...

  7. 20 CFR 404.750 - Evidence of a parent's support.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... DISABILITY INSURANCE (1950- ) Evidence Evidence for Child's and Parent's Benefits § 404.750 Evidence of a parent's support. If you apply for parent's benefits, we will ask you for evidence to show that you... 20 Employees' Benefits 2 2013-04-01 2013-04-01 false Evidence of a parent's support. 404.750...

  8. 20 CFR 404.750 - Evidence of a parent's support.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... DISABILITY INSURANCE (1950- ) Evidence Evidence for Child's and Parent's Benefits § 404.750 Evidence of a parent's support. If you apply for parent's benefits, we will ask you for evidence to show that you... 20 Employees' Benefits 2 2014-04-01 2014-04-01 false Evidence of a parent's support. 404.750...

  9. 20 CFR 404.750 - Evidence of a parent's support.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... DISABILITY INSURANCE (1950- ) Evidence Evidence for Child's and Parent's Benefits § 404.750 Evidence of a parent's support. If you apply for parent's benefits, we will ask you for evidence to show that you... 20 Employees' Benefits 2 2012-04-01 2012-04-01 false Evidence of a parent's support. 404.750...

  10. 12 CFR 750.7 - Applicability in the event of liquidation or conservatorship.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 7 2014-01-01 2014-01-01 false Applicability in the event of liquidation or conservatorship. 750.7 Section 750.7 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS GOLDEN PARACHUTE AND INDEMNIFICATION PAYMENTS § 750.7 Applicability in the event of...

  11. 20 CFR 641.750 - Will there be performance-related incentives?

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Will there be performance-related incentives? 641.750 Section 641.750 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF... incentive awards. The Department will exercise this authority at its discretion. ...

  12. 21 CFR 556.750 - Virginiamycin.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.750 Virginiamycin. (a) Acceptable daily intake (ADI). The ADI for total...

  13. 21 CFR 556.750 - Virginiamycin.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.750 Virginiamycin. (a) Acceptable daily intake (ADI). The ADI for total...

  14. 21 CFR 556.750 - Virginiamycin.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.750 Virginiamycin. (a) Acceptable daily intake (ADI). The ADI for total...

  15. 27 CFR 7.50 - Application.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... THE TREASURY LIQUORS LABELING AND ADVERTISING OF MALT BEVERAGES Advertising of Malt Beverages § 7.50... outdoor advertisement, or in any other printed or graphic matter, any advertisement of malt beverages, if such advertising is in, or is calculated to induce sales in, interstate or foreign commerce, or is...

  16. 48 CFR 750.7109-2 - Form of requests by contractors.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Form of requests by contractors. 750.7109-2 Section 750.7109-2 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect...

  17. 750 Reasons To Celebrate Chemistry!

    PubMed

    Compton, Neville

    2017-06-12

    Time to reflect: This issue marks the 750th issue of Chemistry-A European Journal. The journal has played a significant role in changing chemistry. Its history has featured top papers from top authors for more than 20 years. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. 48 CFR 750.7110-2 - Office of General Counsel coordination.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Office of General Counsel coordination. 750.7110-2 Section 750.7110-2 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT MANAGEMENT EXTRAORDINARY CONTRACTUAL ACTIONS Extraordinary Contractual Actions To Protect Foreign Policy Interests of th...

  19. 48 CFR 750.7110-1 - Investigation.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 750.7110-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... contracting officer makes a thorough investigation of all facts and issues relevant to each situation. Facts and evidence shall be obtained from contractor and Government personnel and shall include signed...

  20. 48 CFR 750.7110-1 - Investigation.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Section 750.7110-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... contracting officer makes a thorough investigation of all facts and issues relevant to each situation. Facts and evidence shall be obtained from contractor and Government personnel and shall include signed...

  1. 48 CFR 750.7110-1 - Investigation.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 750.7110-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... contracting officer makes a thorough investigation of all facts and issues relevant to each situation. Facts and evidence shall be obtained from contractor and Government personnel and shall include signed...

  2. 48 CFR 750.7110-1 - Investigation.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 750.7110-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CONTRACT... contracting officer makes a thorough investigation of all facts and issues relevant to each situation. Facts and evidence shall be obtained from contractor and Government personnel and shall include signed...

  3. 750 GeV diphotons: implications for supersymmetric unification

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hall, Lawrence J.; Harigaya, Keisuke; Nomura, Yasunori

    2016-03-03

    A recent signal of 750 GeV diphotons at the LHC can be explained within the framework of supersymmetric unification by the introduction of vector quarks and leptons with Yukawa couplings to a singlet S that describes the 750 GeV resonance. We study the most general set of theories that allow successful gauge coupling unification, and find that these Yukawa couplings are severely constrained by renormalization group behavior: they are independent of ultraviolet physics and flow to values at the TeV scale that we calculate precisely. As a consequence the vector quarks and leptons must be light; typically in the regionmore » of 375 GeV to 700 GeV, and in certain cases up to 1 TeV. The 750 GeV resonance may have a width less than the experimental resolution; alternatively, with the mass splitting between scalar and pseudoscalar components of S arising from one-loop diagrams involving vector fermions, we compute an apparent width of 10s of GeV.« less

  4. 7 CFR 3560.750 - OMB control number.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

  5. 7 CFR 3560.750 - OMB control number.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

  6. 7 CFR 3560.750 - OMB control number.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

  7. 7 CFR 3560.750 - OMB control number.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

  8. 7 CFR 3560.750 - OMB control number.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... AGRICULTURE DIRECT MULTI-FAMILY HOUSING LOANS AND GRANTS Unauthorized Assistance § 3560.750 OMB control number..., including time for reviewing instructions, searching existing data sources, gathering and maintaining the...

  9. 23 CFR 750.709 - On-property or on-premise advertising.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false On-property or on-premise advertising. 750.709 Section... exempt from control under 23 U.S.C. 131 if they solely advertise the sale or lease of property on which... signs are subject to regulation (subpart A, part 750, chapter I, 23 CFR) in those States which have...

  10. 48 CFR 750.7110-3 - Submission of cases to the M/OP Director.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... M/OP Director. 750.7110-3 Section 750.7110-3 Federal Acquisition Regulations System AGENCY FOR... Actions To Protect Foreign Policy Interests of the United States 750.7110-3 Submission of cases to the M/OP Director. Cases to be submitted for consideration by the M/OAA Director shall be prepared and...

  11. Demonstration of SiC Pressure Sensors at 750 C

    NASA Technical Reports Server (NTRS)

    Okojie, Robert S.; Lukco, Dorothy; Nguyen, Vu; Savrun, Ender

    2014-01-01

    We report the first demonstration of MEMS-based 4H-SiC piezoresistive pressure sensors tested at 750 C and in the process confirmed the existence of strain sensitivity recovery with increasing temperature above 400 C, eventually achieving near or up to 100% of the room temperature values at 750 C. This strain sensitivity recovery phenomenon in 4H-SiC is uncharacteristic of the well-known monotonic decrease in strain sensitivity with increasing temperature in silicon piezoresistors. For the three sensors tested, the room temperature full-scale output (FSO) at 200 psig ranged between 29 and 36 mV. Although the FSO at 400 C dropped by about 60%, full recovery was achieved at 750 C. This result will allow the operation of SiC pressure sensors at higher temperatures, thereby permitting deeper insertion into the engine combustion chamber to improve the accurate quantification of combustor dynamics.

  12. 23 CFR 750.305 - Federal participation.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.305 Federal participation. (a) Federal funds may participate in: (1) Payments made to a sign owner for his right, title and...

  13. 23 CFR 750.706 - Sign control in zoned and unzoned commercial and industrial areas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Sign control in zoned and unzoned commercial and industrial areas. 750.706 Section 750.706 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising Control § 750.706 Sign...

  14. 33 CFR 80.750 - Sanibel Island, FL to St. Petersburg, FL.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Sanibel Island, FL to St. Petersburg, FL. 80.750 Section 80.750 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND... St. Petersburg, FL. (a) A line formed by the centerline of the highway bridge over Blind Pass...

  15. Changes in soil water availability in vineyards can be traced by the carbon and nitrogen isotope composition of dried wines.

    PubMed

    Spangenberg, Jorge E; Zufferey, Vivian

    2018-04-13

    The grapevine is one of the most important edible fruit plants cultivated worldwide, and it is highly sensitive to changes in the soil water content. We studied the total carbon and nitrogen contents and stable isotope compositions (C/N WSR , δ 13 C WSR and δ 15 N WSR values) of the solid residues obtained by freeze-drying wines produced from two white grapevine cultivars (Vitis vinifera L. cv Chasselas and Petite Arvine) field grown under different soil water regimes while maintaining other climatic and ecopedological conditions identical. These experiments simulated the more frequent and extended climate change-induced periods of soil water shortage. The wines were from the 2009-2014 vintages, produced using the same vinification procedure. The plant water status, reflecting soil water availability, was assessed by the predawn leaf water potential (Ψ pd ), monitored in the field during the growing seasons. For both wine varieties, the δ 13 C WSR values are highly correlated with Ψ pd values and record the soil water availability set by soil water holding capacity, rainfall and irrigation water supply. These relationships were the same as those observed for the carbon isotope composition of fruit sugars (i.e., must sugars) and plant water status. In Chasselas wines, the nitrogen content and δ 15 N WSR values decreased with soil water deficit, indicating control of the flux of soil-water soluble nutrients into plants by soil water availability. Such a correlation was not found for Petite Arvine, probably due to different N-metabolism processes in this genetically atypical cultivar. The results presented in this study confirm and generalize what was previously found for red wine (Pinot noir); the carbon isotope composition of wine solid residues is a reliable indicator of the soil and the plant water status and thus can be used to trace back local climatic conditions in the vineyard's region. In most wines (except Petite Arvine) the C/N WSR and δ 15 N WSR

  16. 23 CFR 750.710 - Landmark signs.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Outdoor Advertising Control § 750.710 Landmark signs. (a) 23 U.S.C. 131(c) permits the existence of signs lawfully in existence on October 22, 1965, determined by the State, subject to the approval of the... artistic significance, the preservation of which is consistent with the purpose of 23 U.S.C. 131. (b...

  17. 23 CFR 750.710 - Landmark signs.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Outdoor Advertising Control § 750.710 Landmark signs. (a) 23 U.S.C. 131(c) permits the existence of signs lawfully in existence on October 22, 1965, determined by the State, subject to the approval of the... artistic significance, the preservation of which is consistent with the purpose of 23 U.S.C. 131. (b...

  18. Bioavailability enhancement of baclofen by gastroretentive floating formulation: statistical optimization, in vitro and in vivo pharmacokinetic studies.

    PubMed

    Thakar, Krishna; Joshi, Garima; Sawant, Krutika K

    2013-06-01

    The study was aimed to improve bioavailability of baclofen by developing gastroretentive floating drug delivery system (GFDDS). Preliminary optimization was done to select various release retardants to obtain minimum floating lag time, maximum floating duration and sustained release. Optimization by 3(2) factorial design was done using Polyox WSR 303 (X1) and HPMC K4M (X2) as independent variables and cumulative percentage drug released at 6 h (Q6h) as dependent variable. Optimized formulation showed floating lag time of 4-5 s, floated for more than 12 h and released the drug in sustained manner. In vitro release followed zero ordered kinetics and when fitted to Korsemeyer Peppas model, indicated drug release by combination of diffusion as well as chain relaxation. In vivo floatability study confirmed floatation for more than 6 h. In vivo pharmacokinetic studies in rabbits showed Cmax of 189.96 ± 13.04 ng/mL and Tmax of 4 ± 0.35 h for GFDDS. The difference for AUC(0-T) and AUC(0-∞) between the test and reference formulation was statistically significant (p > 0.05). AUC(0-T) and AUC(0-∞) for GFDDS was 2.34 and 2.43 times greater than the marketed formulation respectively. GFDDS provided prolonged gastric residence and showed significant increase in bioavailability of baclofen.

  19. ZNF750 is a p63 Target Gene that Induces KLF4 to Drive Terminal Epidermal Differentiation

    PubMed Central

    Sen, George L.; Boxer, Lisa D.; Webster, Dan E.; Bussat, Rose T.; Qu, Kun; Zarnegar, Brian J.; Johnston, Danielle; Siprashvili, Zurab; Khavari, Paul A.

    2012-01-01

    SUMMARY Disrupted epidermal differentiation characterizes numerous diseases that impact >25% of the population. In a search for dominant mediators of differentiation, we defined a requirement for ZNF750 in terminal epidermal differentiation. ZNF750 controlled genes mutated in numerous human skin diseases, including FLG, LOR, LCE3B, ALOXE3, and SPINK5. ZNF750 induced progenitor differentiation via an evolutionarily conserved C2H2 zinc finger motif. The epidermal master regulator, p63, bound the ZNF750 promoter and was necessary for its induction. ZNF750 restored differentiation to p63-deficient tissue, suggesting it acts downstream of p63. A search for functionally important ZNF750 targets via analysis of ZNF750-regulated genes identified KLF4, a transcription factor that activates late epidermal differentiation. ZNF750 binds to KLF4 at multiple sites flanking the transcriptional start site and controls its expression. ZNF750 thus directly links a tissue-specifying factor, p63, to an effector of terminal differentiation, KLF4, and represents a potential future target for disorders of this process. PMID:22364861

  20. 23 CFR 750.107 - Class 3 and 4 signs outside informational sites.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Class 3 and 4 signs outside informational sites. 750.107 Section 750.107 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Regulation by States of Outdoor Advertising Adjacent...

  1. Improved nickel plating of Inconel X-750

    NASA Technical Reports Server (NTRS)

    Farmer, M. E.; Feeney, J. E.; Kuster, C. A.

    1969-01-01

    Electroplating technique with acid pickling provides a method of applying nickel plating on Inconel X-750 tubing to serve as a wetting agent during brazing. Low-stress nickel-plating bath contains no organic wetting agents that cause the nickel to blister at high temperatures.

  2. 47 CFR 74.750 - Transmission system facilities.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Translator, and TV Booster Stations § 74.750 Transmission system facilities. (a) A low power TV, TV translator, or TV booster station shall operate with a transmitter that is either certificated for licensing... rebroadcasting TV booster transmitting equipment using a modulation process must meet the following requirements...

  3. 47 CFR 74.750 - Transmission system facilities.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Translator, and TV Booster Stations § 74.750 Transmission system facilities. (a) A low power TV, TV translator, or TV booster station shall operate with a transmitter that is either certificated for licensing... rebroadcasting TV booster transmitting equipment using a modulation process must meet the following requirements...

  4. 47 CFR 74.750 - Transmission system facilities.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Translator, and TV Booster Stations § 74.750 Transmission system facilities. (a) A low power TV, TV translator, or TV booster station shall operate with a transmitter that is either certificated for licensing... rebroadcasting TV booster transmitting equipment using a modulation process must meet the following requirements...

  5. 32 CFR 750.3 - Investigations: The report.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... questions of who, what, where, when, why and how? The Navy's best interests are served when the... responsibility: (1) To interview all witnesses to the incident and prepare summaries of their comments. Obtaining... written report of investigation shall contain information answering the questions mentioned in § 750.3(a...

  6. 32 CFR 750.3 - Investigations: The report.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... questions of who, what, where, when, why and how? The Navy's best interests are served when the... responsibility: (1) To interview all witnesses to the incident and prepare summaries of their comments. Obtaining... written report of investigation shall contain information answering the questions mentioned in § 750.3(a...

  7. 23 CFR 750.107 - Class 3 and 4 signs outside informational sites.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... areas. (6) Not more than one such sign advertising activities being conducted as a single enterprise or... 23 Highways 1 2011-04-01 2011-04-01 false Class 3 and 4 signs outside informational sites. 750.107... to the Interstate System Under the 1958 Bonus Program § 750.107 Class 3 and 4 signs outside...

  8. 23 CFR 750.107 - Class 3 and 4 signs outside informational sites.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... areas. (6) Not more than one such sign advertising activities being conducted as a single enterprise or... 23 Highways 1 2010-04-01 2010-04-01 false Class 3 and 4 signs outside informational sites. 750.107... to the Interstate System Under the 1958 Bonus Program § 750.107 Class 3 and 4 signs outside...

  9. 47 CFR 74.750 - Transmission system facilities.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Translator, and TV Booster Stations § 74.750 Transmission system facilities. (a) A low power TV, TV translator, or TV booster station shall operate with a transmitter that is either certificated for licensing... and TV translator transmitters will be certificated by the FCC: (1) The equipment shall be so designed...

  10. 32 CFR 750.48 - Measure of damages in injury or death cases.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 5 2011-07-01 2011-07-01 false Measure of damages in injury or death cases. 750... GENERAL CLAIMS REGULATIONS Military Claims Act § 750.48 Measure of damages in injury or death cases. (a... possessions, determine the measure of damages under the law of the location where the injury arises. (b) Where...

  11. 32 CFR 750.48 - Measure of damages in injury or death cases.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 5 2012-07-01 2012-07-01 false Measure of damages in injury or death cases. 750... GENERAL CLAIMS REGULATIONS Military Claims Act § 750.48 Measure of damages in injury or death cases. (a... possessions, determine the measure of damages under the law of the location where the injury arises. (b) Where...

  12. 32 CFR 750.48 - Measure of damages in injury or death cases.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 5 2014-07-01 2014-07-01 false Measure of damages in injury or death cases. 750... GENERAL CLAIMS REGULATIONS Military Claims Act § 750.48 Measure of damages in injury or death cases. (a... possessions, determine the measure of damages under the law of the location where the injury arises. (b) Where...

  13. 32 CFR 750.48 - Measure of damages in injury or death cases.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 5 2013-07-01 2013-07-01 false Measure of damages in injury or death cases. 750... GENERAL CLAIMS REGULATIONS Military Claims Act § 750.48 Measure of damages in injury or death cases. (a... possessions, determine the measure of damages under the law of the location where the injury arises. (b) Where...

  14. 32 CFR 750.48 - Measure of damages in injury or death cases.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Measure of damages in injury or death cases. 750... GENERAL CLAIMS REGULATIONS Military Claims Act § 750.48 Measure of damages in injury or death cases. (a... possessions, determine the measure of damages under the law of the location where the injury arises. (b) Where...

  15. 23 CFR 750.104 - Signs that may not be permitted in protected areas.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 23 Highways 1 2012-04-01 2012-04-01 false Signs that may not be permitted in protected areas. 750.104 Section 750.104 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION National Standards for Regulation by States of Outdoor...

  16. 30 CFR 750.14 - Lands designated unsuitable for mining by Act of Congress.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Lands designated unsuitable for mining by Act of Congress. 750.14 Section 750.14 Mineral Resources OFFICE OF SURFACE MINING RECLAMATION AND ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN LANDS PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND...

  17. 40 CFR 7.50 - Specific prohibitions against discrimination.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Discrimination Prohibited on the Basis of Handicap § 7.50 Specific prohibitions against discrimination. (a) A... provided to others; (3) Aid or perpetuate discrimination against a qualified handicapped person by... have the effect of subjecting individuals to discrimination because of their handicap, or have the...

  18. 40 CFR 7.50 - Specific prohibitions against discrimination.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Discrimination Prohibited on the Basis of Handicap § 7.50 Specific prohibitions against discrimination. (a) A... provided to others; (3) Aid or perpetuate discrimination against a qualified handicapped person by... have the effect of subjecting individuals to discrimination because of their handicap, or have the...

  19. 40 CFR 7.50 - Specific prohibitions against discrimination.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Discrimination Prohibited on the Basis of Handicap § 7.50 Specific prohibitions against discrimination. (a) A... provided to others; (3) Aid or perpetuate discrimination against a qualified handicapped person by... have the effect of subjecting individuals to discrimination because of their handicap, or have the...

  20. 40 CFR 7.50 - Specific prohibitions against discrimination.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Discrimination Prohibited on the Basis of Handicap § 7.50 Specific prohibitions against discrimination. (a) A... provided to others; (3) Aid or perpetuate discrimination against a qualified handicapped person by... have the effect of subjecting individuals to discrimination because of their handicap, or have the...

  1. 40 CFR 7.50 - Specific prohibitions against discrimination.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Discrimination Prohibited on the Basis of Handicap § 7.50 Specific prohibitions against discrimination. (a) A... provided to others; (3) Aid or perpetuate discrimination against a qualified handicapped person by... have the effect of subjecting individuals to discrimination because of their handicap, or have the...

  2. 21 CFR 358.750 - Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... dandruff, seborrheic dermatitis, or psoriasis. 358.750 Section 358.750 Food and Drugs FOOD AND DRUG... Dermatitis, and Psoriasis § 358.750 Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis. (a) Statement of identity. The labeling of the product contains the established...

  3. 21 CFR 358.750 - Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... dandruff, seborrheic dermatitis, or psoriasis. 358.750 Section 358.750 Food and Drugs FOOD AND DRUG... Dermatitis, and Psoriasis § 358.750 Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis. (a) Statement of identity. The labeling of the product contains the established...

  4. Acute kidney injury in ELBW infants (<  750 grams) and its associated risk factors.

    PubMed

    Arcinue, R; Kantak, A; Elkhwad, M

    2015-01-01

    The advancement of neonatology over the past 20 years has allowed a greater number of ELBW infants to survive. However, these advancements have contributed to the increased incidence of acute kidney injury (AKI) seen in this population. Understanding the risk factors for AKI in this population of ELBW infants is imperative for the successful survival of these infants since the morbidity and mortality rates from this disease are increasing. 1) to determine the prevalence of AKI in ELBW (<  750 grams). 2) to compare the mortality rate of ELBW infants (<  750 grams) with and without AKI; and 3) to identify the associated risk factors of AKI in ELBW infants (<  750 grams). A retrospective chart review of all infants with AKI as defined by AKIN criterias, admitted to the NICU between 1998 and 2008 was conducted. Case-controls were matched for BW, gestational age and date of birth, (SPSS v17.0 software, using Student's t test, X2 test, and Mann-Whitney U test were used for statistical analysis. The prevalence rate of ELBW infants (<  750 grams) with AKI admitted at CHMCA NICU from 1998 to 2008 was 26% . The mortality rate of ELBW infants (<  750 grams) with AKI was 54% , compared to 20% in those ELBW infants who did not have AKI. The associated risk factors of AKI in the ELBW infants (<  750 grams) were as follows: presence of maternal placental abruption/bleeding, grade III or IV IVH, PDA, positive culture/s, NEC, use of steroid, nephrotoxic drugs, and longer use of the ventilator and TPN.

  5. 23 CFR 750.304 - State policies and procedures.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... one company or those located along a single route, all of the signs in a single county or other... BEAUTIFICATION Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.304 State policies and procedures. The State's written policies and operating procedures for implementing its sign...

  6. 23 CFR 750.304 - State policies and procedures.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... one company or those located along a single route, all of the signs in a single county or other... BEAUTIFICATION Outdoor Advertising (Acquisition of Rights of Sign and Sign Site Owners) § 750.304 State policies and procedures. The State's written policies and operating procedures for implementing its sign...

  7. 38 CFR 3.750 - Entitlement to concurrent receipt of military retired pay and disability compensation.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... disability compensation. (a) Definition of military retired pay. For the purposes of this part, military... compensation. A veteran may reelect between benefits covered by this section at any time by submitting a... receipt of military retired pay and disability compensation. 3.750 Section 3.750 Pensions, Bonuses, and...

  8. Limited energy study, Buildings 750 and 798, Fort Richardson, Alaska. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1996-02-01

    The purpose of this study is to identify and evaluate Energy Conservation Opportunities (ECOs) for two motor pool facilities, Buildings 750 and 798, to determine their energy savings potential, economic feasibility, and to document results for possible future funding. Buildings 750 and 798 are heated by steam supplied from a central plant. The central plant uses natural gas as a primary fuel source to produce steam for both heating and electrical energy generation. Since power is produced on the base there is not a demand charge for electrical energy. Two ECOs examined the use of natural gas in conjunction withmore » steam as a method of heating the buildings. Annual baseline energy consumption and cost data for each building is presented. The heating system in Building 750 was found to be severely under capacity. This is the result of the disabling of the under-floor heating system and the roof top MAUs. Building 798 also has had the under-floor heating system disabled. However, baseline simulations show that the remaining system is capable of maintaining thermostat setpoints during all but the coldest days of a typical year.« less

  9. Development and optimization of press coated floating pulsatile drug delivery of sumatriptan succinate.

    PubMed

    Jagdale, Swati C; Pawar, Chandrakala R

    2014-01-01

    Floating pulsatile is combined approach designed according to circadian rhythm to deliver the drug at right time, in right quantity and at right site as per pathophysiological need of disease with prolong gastric residence and lag phase followed by burst release. As the migraine follows circadian rhythm in which headache is more painful at the awakening time, the dosage form should be given during night time to release drug when pain get worsen. Present work deals with formulation and optimization of floating pulsatile tablet of sumatriptan succinate. Core tablet containing crospovidone as superdisintegrant (10%) showed burst release. Lag time was maintained using swellable polymer as polyoxN12K and xanthum gum. 3(2) experimental design was carried out. Developed formulations were evaluated for physical characteristics, in vitro and in vivo study. Optimized batch F2 with concentration of polyox N12K (73.43%) and xanthum gum (26.56%) of total polymer weight showed floating lag time 15±2 sec, drug content 99.58±0.2 %, hardness 6±0.2 Kg/cm(2) and drug release 99.54±2% with pulsatile manner followed lag period of 7±0.1h. In vivo x-ray study confirms prolong gastric residence of system. Programmable pulsatile release has been achieved by formulation F2 which meet demand of chronotherapeutic objective of migraine.

  10. Development of Multiple-Unit Floating Drug Delivery System of Clarithromycin: Formulation, in vitro Dissolution by Modified Dissolution Apparatus, in vivo Radiographic Studies in Human Volunteers.

    PubMed

    Reddy, Arun B; Reddy, Narendar D

    2017-07-01

    Clarithromycin (CM), a broad spectrum macrolide antibiotic used to eradicate H. pylori in peptic ulcer. Clarithromycin (CM) is well absorbed from the gastrointestinal tract, but has a bioavailability of 50% due to rapid biodegradation. The aim of this investigation was to increase the gastric residence time, and to control the drug release of clarithromycin by formulating into multiple unit floating mini-tablets. Floating tablets were prepared by using direct compression method with HPMC K 4 M and Polyox WSR 1105 as release retarded polymers and sodium bicarbonate as gas generating agent. The prepared mini-tablets were evaluated for thickness, weight variation, friability, hardness, drug content, in vitro buoyancy, swelling studies, in vitro dissolution studies by using modified Rossett-Rice test and in vivo radiographic studies in healthy human volunteers in fasting conditions. DSC analysis revealed that no interaction between drug and excipients. All the physical parameters of the tablets were within the acceptable limits. The optimized formulation (F6) had showed controlled drug release of 99.16±3.22% in 12 h, by zero-order release kinetics, along with floating lag time of 9.5±1.28 s and total floating time of 12±0.14 h. X-ray imaging studies revealed that in vivo gastric residence time of clarithromycin floating mini-tablet in the stomach was about 3.5 h. The results demonstrated that the developed floating mini-tablets of clarithromycin caused significant enhancement in gastric retention time along with sustained effect and increased oral bioavailability. © Georg Thieme Verlag KG Stuttgart · New York.

  11. A novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) specifically detects CXCR4 expressing tumors.

    PubMed

    Santagata, Sara; Portella, Luigi; Napolitano, Maria; Greco, Adelaide; D'Alterio, Crescenzo; Barone, Maria Vittoria; Luciano, Antonio; Gramanzini, Matteo; Auletta, Luigi; Arra, Claudio; Zannetti, Antonella; Scala, Stefania

    2017-05-31

    C-X-C chemokine receptor 4 (CXCR4) is over-expressed in multiple human cancers and correlates with tumor aggressiveness, poor prognosis and increased risk for distant metastases. Imaging agents for CXCR4 are thus highly desirable. We developed a novel CXCR4-targeted near-infrared (NIR) fluorescent probe (Peptide R-NIR750) conjugating the new developed CXCR4 peptidic antagonist Peptide R with the NIR fluorescent dye VivoTag-S750. Specific CXCR4 binding was obtained in cells overexpressing human CXCR4 (B16-hCXCR4 and human melanoma cells PES43), but not in CXCR4 low expressing cells (FB-1). Ex vivo evaluation demonstrated that PepR-NIR750 specifically detects B16-hCXCR4-derived subcutaneous tumors and lung metastases. Fluorescence Molecular Tomography (FMT) in vivo imaging was performed on mice carrying subcutaneous CHO and CHO-CXCR4 tumors. PepR-NIR750 accumulates only in CXCR4-positive expressing subcutaneous tumors. Additionally, an intense NIR fluorescence signal was detected in PES43-derived lung metastases of nude mice injected with PepR-NIR750 versus mice injected with VivoTag-S750. With a therapeutic intent, mice bearing PES43-derived lung metastases were treated with Peptide R. A the dramatic reduction in PES43-derived lung metastases was detected through a decrease of the PepR-NIR750 signal. PepR-NIR750 is a specific probe for non-invasive detection of human high CXCR4-expressing tumors and metastatic lesion and thus a valuable tool for cancer molecular imaging.

  12. 40 CFR 1033.750 - Changing a locomotive's FEL at remanufacture.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Changing a locomotive's FEL at... Certification § 1033.750 Changing a locomotive's FEL at remanufacture. Locomotives are generally required to be... revised FEL for the remainder of their service lives, unless it is changed again under this section during...

  13. 40 CFR 1033.750 - Changing a locomotive's FEL at remanufacture.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 33 2011-07-01 2011-07-01 false Changing a locomotive's FEL at... Certification § 1033.750 Changing a locomotive's FEL at remanufacture. Locomotives are generally required to be... revised FEL for the remainder of their service lives, unless it is changed again under this section during...

  14. ASCEND-8: A Randomized Phase 1 Study of Ceritinib, 450 mg or 600 mg, Taken with a Low-Fat Meal versus 750 mg in Fasted State in Patients with Anaplastic Lymphoma Kinase (ALK)-Rearranged Metastatic Non-Small Cell Lung Cancer (NSCLC).

    PubMed

    Cho, Byoung Chul; Kim, Dong-Wan; Bearz, Alessandra; Laurie, Scott A; McKeage, Mark; Borra, Gloria; Park, Keunchil; Kim, Sang-We; Ghosn, Marwan; Ardizzoni, Andrea; Maiello, Evaristo; Greystoke, Alastair; Yu, Richard; Osborne, Karen; Gu, Wen; Scott, Jeffrey W; Passos, Vanessa Q; Lau, Yvonne Y; Wrona, Anna

    2017-09-01

    Ceritinib, 750 mg fasted, is approved for treatment of patients with ALK receptor tyrosine kinase gene (ALK)-rearranged (ALK-positive) NSCLC previously treated with crizotinib. Part 1 of the ASCEND-8 study determined whether administering ceritinib, 450 mg or 600 mg, with a low-fat meal may enhance gastrointestinal (GI) tolerability versus 750 mg fasted in patients with ALK-positive NSCLC while maintaining similar exposure. ASCEND-8 is a multicenter, randomized, open-label, phase 1 study. Part 1 investigated the steady-state pharmacokinetics (PK) and safety of ceritinib, 450 mg or 600 mg, taken with a low-fat meal versus 750 mg fasted in patients with advanced ALK-positive NSCLC who were either treatment naive or pretreated with chemotherapy and/or crizotinib. Part 2 will assess efficacy and safety of ceritinib in treatment-naive patients. As of June 16, 2016, 137 patients were randomized (450 mg fed [n = 44], 600 mg fed [n = 47], and 750 mg fasted [n = 46]); 135 patients received ceritinib. Median follow-up duration was 4.14 months. At steady state, relative to 750 mg fasted, 450 mg with food demonstrated comparable PK as assessed by maximum (peak) concentration of drug in plasma and area under the plasma concentration-time curve from time zero to 24 hours, whereas 600 mg with food demonstrated approximately 25% higher PK. Relative to 750 mg fasted, 450 mg with food was associated with a lower proportion of patients with GI toxicities, mostly grade 1 (diarrhea [43.2%], nausea [29.5%], and vomiting [18.2%]); there were no grade 3 or 4 events, study drug discontinuations, or serious AEs due to GI toxicities. Ceritinib, 450 mg with food, had similar exposure and a more favorable GI safety profile than ceritinib, 750 mg in fasted patients with ALK-positive NSCLC. Copyright © 2017 International Association for the Study of Lung Cancer. Published by Elsevier Inc. All rights reserved.

  15. 48 CFR 750.7110-4 - Processing by M/OAA Director.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Processing by M/OAA... Foreign Policy Interests of the United States 750.7110-4 Processing by M/OAA Director. When the action memorandum has been determined to be as accurate and complete as possible and has been prepared in accordance...

  16. 48 CFR 750.7110-4 - Processing by M/OAA Director.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 48 Federal Acquisition Regulations System 5 2012-10-01 2012-10-01 false Processing by M/OAA... Foreign Policy Interests of the United States 750.7110-4 Processing by M/OAA Director. When the action memorandum has been determined to be as accurate and complete as possible and has been prepared in accordance...

  17. 48 CFR 750.7110-4 - Processing by M/OAA Director.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Processing by M/OAA... Foreign Policy Interests of the United States 750.7110-4 Processing by M/OAA Director. When the action memorandum has been determined to be as accurate and complete as possible and has been prepared in accordance...

  18. Detection of breast cancer microcalcification using (99m)Tc-MDP SPECT or Osteosense 750EX FMT imaging.

    PubMed

    Felix, Dayo D; Gore, John C; Yankeelov, Thomas E; Peterson, Todd E; Barnes, Stephanie; Whisenant, Jennifer; Weis, Jared; Shoukouhi, Sepideh; Virostko, John; Nickels, Michael; McIntyre, J Oliver; Sanders, Melinda; Abramson, Vandana; Tantawy, Mohammed N

    2015-03-01

    In previous work, we demonstrated the presence of hydroxyapetite (type II microcalcification), HAP, in triple negative MDA-MB-231 breast cancer cells. We used (18)F-NaF to detect these types of cancers in mouse models as the free fluorine, (18)F(-), binds to HAP similar to bone uptake. In this work, we investigate other bone targeting agents and techniques including (99m)Tc-MDP SPECT and Osteosense 750EX FMT imaging as alternatives for breast cancer diagnosis via targeting HAP within the tumor microenvironment. Thirteen mice were injected subcutaneously in the right flank with 10(6) MDA-MB-231 cells. When the tumor size reached ~0.6 cm(3), mice (n=9) were injected with ~37 MBq of (99m)Tc-MDP intravenously and then imaged one hour later in a NanoSPECT/CT or injected intravenously with 4 nmol/g of Osetosense 750EX and imaged 24 hours later in an FMT (n=4). The imaging probe concentration in the tumor was compared to that of muscle. Following SPECT imaging, the tumors were harvested, sectioned into 10 μm slices, and underwent autoradiography or von Kossa staining to correlate (99m)Tc-MDP binding with HAP distribution within the tumor. The SPECT images were normalized to the injected dose and regions-of-interest (ROIs) were drawn around bone, tumor, and muscle to obtain the radiotracer concentration in these regions in units of percent injected dose per unit volume. ROIs were drawn around bone and tumor in the FMT images as no FMT signal was observed in normal muscle. Uptake of (99m)Tc-MDP was observed in the bone and tumor with little or no uptake in the muscle with concentrations of 11.34±1.46 (mean±SD), 2.22±0.95, and 0.05±0.04%ID/cc, respectively. Uptake of Osteosense 750EX was also observed in the bone and tumor with concentrations of 0.35±0.07 (mean±SD) and 0.04±0.01picomoles, respectively. No FMT signal was observed in the normal muscle. There was no significant difference in the bone-to-tumor ratio between the two modalities (5.1±2.3 for SPECT and 8.8

  19. 23 CFR 750.711 - Structures which have never displayed advertising material.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Structures which have never displayed advertising... RIGHT-OF-WAY AND ENVIRONMENT HIGHWAY BEAUTIFICATION Outdoor Advertising Control § 750.711 Structures which have never displayed advertising material. Structures, including poles, which have never displayed...

  20. Inter-Comparison of CHARM Data and WSR-88D Storm Integrated Rainfall

    NASA Technical Reports Server (NTRS)

    Jedlovec, Gary J.; Meyer, Paul J.; Guillory, Anthony R.; Stellman, Keith; Limaye, Ashutosh; Arnold, James E. (Technical Monitor)

    2002-01-01

    A localized precipitation network has been established over a 4000 sq km region of northern Alabama in support of local weather and climate research at the Global Hydrology and Climate Center (GHCC) in Huntsville. This Cooperative Huntsville-Area Rainfall Measurement (CHARM) network is comprised of over 80 volunteers who manually take daily rainfall measurements from 85 sites. The network also incorporates 20 automated gauges that report data at 1-5 minute intervals on a 24 h a day basis. The average spacing of the gauges in the network is about 6 kin, however coverage in some regions benefit from gauges every 1-2 km. The 24 h rainfall totals from the CHARM network have been used to validate Stage III rainfall estimates of daily and storm totals derived from the WSR-88D radars that cover northern Alabama. The Stage III rainfall product is produced by the Lower Mississippi River Forecast Center (LMRFC) in support of their daily forecast operations. The intercomparisons between the local rain gauge and the radar estimates have been useful to understand the accuracy and utility of the Stage III data. Recently, the Stage III and CHARM rainfall measurements have been combined to produce an hourly rainfall dataset at each CHARM observation site. The procedure matches each CHARM site with a time sequence of Stage III radar estimates of precipitation. Hourly stage III rainfall estimates were used to partition the rain gauge values to the time interval over which they occurred. The new hourly rain gauge dataset is validated at selected points where 1-5 minute rainfall measurements have been made. This procedure greatly enhances the utility of the CHARM data for local weather and hydrologic modeling studies. The conference paper will present highlights of the Stage III intercomparison and some examples of the combined radar / rain gauge product demonstrating its accuracy and utility in deriving an hourly rainfall product from the 24 h CHARM totals.

  1. Pharmacokinetics of intravenous levofloxacin administered at 750 milligrams in obese adults.

    PubMed

    Cook, Aaron M; Martin, Craig; Adams, Val R; Morehead, R Scott

    2011-07-01

    The physiochemical properties of levofloxacin suggest that it is an agent which may exhibit altered pharmacokinetics in obese individuals. The purpose of this study was to describe the pharmacokinetics of a single 750-mg intravenous dose of levofloxacin in both hospitalized and ambulatory obese individuals. The hypothesis was that a standard dose of levofloxacin in obese individuals would achieve serum concentrations likely to be therapeutic. A single levofloxacin dose of 750 mg was infused over 90 min, and seven serial serum samples were subsequently obtained to evaluate the pharmacokinetics after the first dose. The peak concentrations of levofloxacin were comparable to those seen with normal-weight individuals. However, the area under the concentration-time curve and clearance were quite variable. Accelerated clearance was evident in the ambulatory obese individuals. Further investigation of the effects of obesity on the pharmacokinetics of levofloxacin is necessary to ensure optimal dosing.

  2. 23 CFR 750.709 - On-property or on-premise advertising.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ..., it shall be considered the business of outdoor advertising and not an on-property sign. (c) A sale or lease sign which also advertises any product or service not conducted upon and unrelated to the business... 23 Highways 1 2010-04-01 2010-04-01 false On-property or on-premise advertising. 750.709 Section...

  3. 48 CFR 750.7110-4 - Processing by M/OAA Director.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Processing by M/OAA... Foreign Policy Interests of the United States 750.7110-4 Processing by M/OAA Director. When the action... with this subpart, M/OAA/E will forward the action memorandum to the M/OAA Director. The M/OAA Director...

  4. 48 CFR 750.7110-4 - Processing by M/OAA Director.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Processing by M/OAA... Foreign Policy Interests of the United States 750.7110-4 Processing by M/OAA Director. When the action... with this subpart, M/OAA/E will forward the action memorandum to the M/OAA Director. The M/OAA Director...

  5. Intergranular fracture in irradiated Inconel X-750 containing very high concentrations of helium and hydrogen

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Judge, Colin D.; Gauquelin, Nicolas; Walters, Lori

    2015-02-01

    In recent years, it has been determined that Inconel X-750 CANDU spacers have lost strength and material ductility following irradiation in reactor. The irradiated fracture behaviour of ex-service material was also found to be entirely intergranular. The heavily thermalized flux spectrum in a CANDU reactor results in transmutation of 58Ni to 59Ni. The 59Ni itself has unusually high thermal neutron reaction cross-sections of the type: (n, γ), (n, p), and (n,α). The latter two reactions, in particular, contribute to a significant enhancement of the atomic displacements in addition to creating high concentrations of hydrogen and helium within the material. Metallographicmore » examinations by transmission electron microscopy (TEM) have confirmed the presence of helium bubbles in the matrix and aligned along grain boundaries and matrix-precipitate interfaces. He bubble size and density are found to be highly dependent on the irradiation temperature and material microstructure; the bubbles are larger within grain boundary precipitates. TEM specimens extracted from fracture surfaces and crack tips give direct evidence linking crack propagation with grain boundary He bubbles.« less

  6. Pharmacodynamics of 750 mg and 500 mg doses of levofloxacin against ciprofloxacin-resistant strains of Streptococcus pneumoniae.

    PubMed

    Lister, Philip D

    2002-09-01

    An in vitro pharmacokinetic model (IVPM) was used to evaluate the pharmacodynamics of the 750 mg and 500 mg doses of levofloxacin against 4 ciprofloxacin-nonsusceptible Streptococcus pneumoniae. Levofloxacin MICs ranged from 1.4 to 3.2 micro g/ml. Log-phase cultures (5 x 10(7) cfu/ml) were inoculated into the IVPM and exposed to the peak free-drug concentrations of levofloxacin achieved in human serum with each dose. Levofloxacin was dosed at 0 and 24 h, elimination pharmacokinetics were simulated, and viable counts were measured over 30 h. The 750 mg dose was rapidly bactericidal against all 4 strains, achieving eradication within 30 h. Against strains with levofloxacin MICs of 1.4 and 1.8 micro g/ml, the 500 mg dose exhibited pharmacodynamics similar to the 750 mg dose. In contrast, against strains with levofloxacin MICs of 2.6 and 3.2 micro g/ml, viable counts never fell below 10(4) cfu/ml. The rapid killing and eradication of these pneumococci by the 750 mg dose warrant the clinical evaluation of this new dose in the treatment of pneumococcal infections.

  7. 33 CFR 80.750 - Sanibel Island, FL to St. Petersburg, FL.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Sanibel Island, FL to St... SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Gulf Coast § 80.750 Sanibel Island, FL to..., between Captiva Island and Sanibel Island, and lines drawn across Redfish and Captiva Passes parallel to...

  8. Efficacy of 750-mg, 5-day levofloxacin in the treatment of community-acquired pneumonia caused by atypical pathogens.

    PubMed

    Dunbar, Lala M; Khashab, Mohammed M; Kahn, James B; Zadeikis, Neringa; Xiang, Jim X; Tennenberg, Alan M

    2004-04-01

    Current recommended durations for treatment of atypical community-acquired pneumonia (CAP) range from 10 to 21 days. However, antibiotics such as the fluoroquinolones may allow for effective, short-course regimens. This study evaluated the efficacy of 750 mg levofloxacin for 5 days compared to a 500-mg, 10-day levofloxacin regimen for the treatment of atypical CAP. A randomized, active-controlled, double-blind, multicenter study was conducted within the United States. Of the 528 patients enrolled in the study, 149 were diagnosed with CAP due to Legionella pneumophila, Chlamydia pneumoniae, or Mycoplasma pneumoniae. Patients' baseline symptoms were re-evaluated on Day 3 of therapy. Clinical efficacy and resolution of CAP symptoms were evaluated at the posttherapy visit (7-14 days after the last dose of active drug). This report represents a subgroup analysis of a previous clinical study. Among the 123 clinically evaluable patients diagnosed with atypical CAP (26 patients were unevaluable), the clinical success rates were 95.5% (63 of 66 patients) for the 750-mg group and 96.5% (55 of 57 patients) for the 500-mg group (95% CI for success rate of the 500-mg group minus that of the 750-mg group, -6.8 to 8.8). At the poststudy evaluation (31-38 days after treatment began), relapse occurred in 750-mg therapy resulted in more rapid symptom resolution, with a significantly greater proportion of patients experiencing resolution of fever by Day 3 of therapy (p = 0.031). The 750-mg, 5-day course of levofloxacin was at least as effective as the 500-mg, 10-day regimen for atypical CAP. Additionally, the 750-mg, short-course levofloxacin therapy may reduce total antimicrobial drug usage and more rapidly relieve pneumonia symptoms.

  9. Photons, photon jets, and dark photons at 750 GeV and beyond.

    PubMed

    Dasgupta, Basudeb; Kopp, Joachim; Schwaller, Pedro

    2016-01-01

    In new physics searches involving photons at the LHC, one challenge is to distinguish scenarios with isolated photons from models leading to "photon jets". For instance, in the context of the 750 GeV diphoton excess, it was pointed out that a true diphoton resonance [Formula: see text] can be mimicked by a process of the form [Formula: see text], where S is a new scalar with a mass of 750 GeV and a is a light pseudoscalar decaying to two collinear photons. Photon jets can be distinguished from isolated photons by exploiting the fact that a large fraction of photons convert to an [Formula: see text] pair inside the inner detector. In this note, we quantify this discrimination power, and we study how the sensitivity of future searches differs for photon jets compared to isolated photons. We also investigate how our results depend on the lifetime of the particle(s) decaying to the photon jet. Finally, we discuss the extension to [Formula: see text], where there are no photons at all but the dark photon [Formula: see text] decays to [Formula: see text] pairs. Our results will be useful in future studies of the putative 750 GeV signal, but also more generally in any new physics search involving hard photons.

  10. Pharmacokinetics of Intravenous Levofloxacin Administered at 750 Milligrams in Obese Adults ▿

    PubMed Central

    Cook, Aaron M.; Martin, Craig; Adams, Val R.; Morehead, R. Scott

    2011-01-01

    The physiochemical properties of levofloxacin suggest that it is an agent which may exhibit altered pharmacokinetics in obese individuals. The purpose of this study was to describe the pharmacokinetics of a single 750-mg intravenous dose of levofloxacin in both hospitalized and ambulatory obese individuals. The hypothesis was that a standard dose of levofloxacin in obese individuals would achieve serum concentrations likely to be therapeutic. A single levofloxacin dose of 750 mg was infused over 90 min, and seven serial serum samples were subsequently obtained to evaluate the pharmacokinetics after the first dose. The peak concentrations of levofloxacin were comparable to those seen with normal-weight individuals. However, the area under the concentration-time curve and clearance were quite variable. Accelerated clearance was evident in the ambulatory obese individuals. Further investigation of the effects of obesity on the pharmacokinetics of levofloxacin is necessary to ensure optimal dosing. PMID:21576432

  11. PA01.81. Impact of globalisation on health w.s.r. metabolic syndrome and its ayurvedic management)

    PubMed Central

    Layeeq, Shaizi; Srivastava, Alok K

    2012-01-01

    Purpose: According to WHO report 2002,Cardiovacular diseases (CVD) will be the largest cause of death and disability in India by 2012. Metabolic Syndrome (MetS), a constellation of dyslipidemia, elevated blood glucose, hypertension and obesity is emerging as the most common risk factor for CVD. The rising prevalence of individual components of Metabolic Syndrome is mainly attributed to globalisation which has made available cheap, unhealthy food on the main menu & also brought with it sedentary lifestyle. It is a need of time to pay due consideration on the problem and search for alternative medicine. So the aim of the study is: 1. To study the impact of globalisation on health w.s.r Metabolic Syndrome. 2. To assess the clinical efficacy of Panchakarma in its management. Method: For the study large-scale survey, other documented data and published articles were studied. For clinical contrieve 20 patients were registered and were given Virechana Karma followed by administration of Shuddha Guggulu as palliative measure. Result: The results show that globalisation has a great impact on all the components of Metabolic Syndrome. However on management with Panchakarma (Virechana Karma) followed by Shuddha Guggulu encouraging results were found. The overall effect of therapy was found to be 82.5%. Conclusion: There is a high prevalence of metabolic syndrome in India and it is a need of time to consider alternative treatment for its management alongwith change in lifestyle to reduce the risk of cardiovascular disease.

  12. Penetration of levofloxacin into skin tissue after oral administration of multiple 750 mg once-daily doses.

    PubMed

    Chow, A T; Chen, A; Lattime, H; Morgan, N; Wong, F; Fowler, C; Williams, R R

    2002-04-01

    To probe the pharmacokinetic basis for the use of levofloxacin for complicated skin and skin-structure infections (SSSIs) at a once-daily dosage of 750 mg by investigating its penetration into skin tissue. Ten healthy volunteers were administered three oral, once-daily 750 mg doses of levofloxacin, and levofloxacin concentrations were subsequently measured over time (0.5-24 h) in skin-punch biopsy tissue and plasma. Skin tissue concentrations consistently exceeded those in plasma at every time point, with tissue/plasma ratios of 1.37 +/- 0.81 for peak concentration and 1.97 +/- 0.35 for area under the concentration versus time curve. Three of the ten subjects reported treatment-emergent adverse events (AEs) that were considered unrelated to treatment. An 11th subject who had enrolled in the study withdrew after AEs of mild severity that were possibly related to the study drug. The results support the clinical usage of levofloxacin 750 mg once-daily for complicated SSSIs.

  13. Double-blind evaluation of the safety and pharmacokinetics of multiple oral once-daily 750-milligram and 1-gram doses of levofloxacin in healthy volunteers.

    PubMed

    Chien, S C; Wong, F A; Fowler, C L; Callery-D'Amico, S V; Williams, R R; Nayak, R; Chow, A T

    1998-04-01

    The safety and pharmacokinetics of once-daily oral levofloxacin in 16 healthy male volunteers were investigated in a randomized, double-blind, placebo-controlled study. Subjects were randomly assigned to the treatment (n = 10) or placebo group (n = 6). In study period 1, 750 mg of levofloxacin or a placebo was administered orally as a single dose on day 1, followed by a washout period on days 2 and 3; dosing resumed for days 4 to 10. Following a 3-day washout period, 1 g of levofloxacin or a placebo was administered in a similar fashion in period 2. Plasma and urine levofloxacin concentrations were measured by high-pressure liquid chromatography. Pharmacokinetic parameters were estimated by model-independent methods. Levofloxacin was rapidly absorbed after single and multiple once-daily 750-mg and 1-g doses with an apparently large volume of distribution. Peak plasma levofloxacin concentration (Cmax) values were generally attained within 2 h postdose. The mean values of Cmax and area under the concentration-time curve from 0 to 24 h (AUC0-24) following a single 750-mg dose were 7.1 microg/ml and 71.3 microg x h/ml, respectively, compared to 8.6 microg/ml and 90.7 microg x h/ml, respectively, at steady state. Following the single 1-g dose, mean Cmax and AUC0-24 values were 8.9 microg/ml and 95.4 microg x h/ml, respectively; corresponding values at steady state were 11.8 microg/ml and 118 microg x h/ml. These Cmax and AUC0-24 values indicate modest and similar degrees of accumulation upon multiple dosing at the two dose levels. Values of apparent total body clearance (CL/F), apparent volume of distribution (Vss/F), half-life (t1/2), and renal clearance (CL[R]) were similar for the two dose levels and did not vary from single to multiple dosing. Mean steady-state values for CL/F, Vss/F, t1/2, and CL(R) following 750 mg of levofloxacin were 143 ml/min, 100 liters, 8.8 h, and 116 ml/min, respectively; corresponding values for the 1-g dose were 146 ml/min, 105 liters, 8

  14. Double-Blind Evaluation of the Safety and Pharmacokinetics of Multiple Oral Once-Daily 750-Milligram and 1-Gram Doses of Levofloxacin in Healthy Volunteers

    PubMed Central

    Chien, Shu-Chean; Wong, Frank A.; Fowler, Cynthia L.; Callery-D’Amico, Susan V.; Williams, R. Rex; Nayak, Ramchandra; Chow, Andrew T.

    1998-01-01

    The safety and pharmacokinetics of once-daily oral levofloxacin in 16 healthy male volunteers were investigated in a randomized, double-blind, placebo-controlled study. Subjects were randomly assigned to the treatment (n = 10) or placebo group (n = 6). In study period 1, 750 mg of levofloxacin or a placebo was administered orally as a single dose on day 1, followed by a washout period on days 2 and 3; dosing resumed for days 4 to 10. Following a 3-day washout period, 1 g of levofloxacin or a placebo was administered in a similar fashion in period 2. Plasma and urine levofloxacin concentrations were measured by high-pressure liquid chromatography. Pharmacokinetic parameters were estimated by model-independent methods. Levofloxacin was rapidly absorbed after single and multiple once-daily 750-mg and 1-g doses with an apparently large volume of distribution. Peak plasma levofloxacin concentration (Cmax) values were generally attained within 2 h postdose. The mean values of Cmax and area under the concentration-time curve from 0 to 24 h (AUC0–24) following a single 750-mg dose were 7.1 μg/ml and 71.3 μg · h/ml, respectively, compared to 8.6 μg/ml and 90.7 μg · h/ml, respectively, at steady state. Following the single 1-g dose, mean Cmax and AUC0–24 values were 8.9 μg/ml and 95.4 μg · h/ml, respectively; corresponding values at steady state were 11.8 μg/ml and 118 μg · h/ml. These Cmax and AUC0–24 values indicate modest and similar degrees of accumulation upon multiple dosing at the two dose levels. Values of apparent total body clearance (CL/F), apparent volume of distribution (Vss/F), half-life (t1/2), and renal clearance (CLR) were similar for the two dose levels and did not vary from single to multiple dosing. Mean steady-state values for CL/F, Vss/F, t1/2, and CLR following 750 mg of levofloxacin were 143 ml/min, 100 liters, 8.8 h, and 116 ml/min, respectively; corresponding values for the 1-g dose were 146 ml/min, 105 liters, 8.9 h, and 105 ml

  15. From the 750 GeV diphoton resonance to multilepton excesses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bae, Kyu Jung; Chen, Chuan-Ren; Hamaguchi, Koichi

    2016-07-01

    Weakly coupled models for the 750 GeV diphoton resonance often invoke new particles carrying both color and/or electric charges to mediate loop-induced couplings of the resonance to two gluons and two photons. The new colored particles may not be stable and could decay into final states containing standard model particles. We consider an electroweak doublet of vectorlike quarks (VLQs) carrying electric charges of 5/3 and 2/3, respectively, which mediate the loop-induced couplings of the 750 GeV resonance. If the VLQ has a mass at around 1 TeV, it naturally gives rise to the observed diphoton signal strength while all couplingsmore » remain perturbative up to a high scale. At the same time, if the charge-5/3 VLQ decays into final states containing top quark and W boson, it would contribute to the multilepton excesses observed in both run 1 and run 2 data. It is also possible to incorporate a dark matter candidate in the decay final states to explain the observed relic density.« less

  16. 7 CFR 782.12 - Filing FSA-750, End-Use Certificate for Wheat.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 7 Agriculture 7 2014-01-01 2014-01-01 false Filing FSA-750, End-Use Certificate for Wheat. 782.12 Section 782.12 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS END-USE CERTIFICATE PROGRAM Implementation of the End-Use...

  17. 7 CFR 782.12 - Filing FSA-750, End-Use Certificate for Wheat.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Filing FSA-750, End-Use Certificate for Wheat. 782.12 Section 782.12 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS END-USE CERTIFICATE PROGRAM Implementation of the End-Use...

  18. 7 CFR 782.12 - Filing FSA-750, End-Use Certificate for Wheat.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 7 Agriculture 7 2011-01-01 2011-01-01 false Filing FSA-750, End-Use Certificate for Wheat. 782.12 Section 782.12 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS END-USE CERTIFICATE PROGRAM Implementation of the End-Use...

  19. 7 CFR 782.12 - Filing FSA-750, End-Use Certificate for Wheat.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 7 Agriculture 7 2013-01-01 2013-01-01 false Filing FSA-750, End-Use Certificate for Wheat. 782.12 Section 782.12 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS END-USE CERTIFICATE PROGRAM Implementation of the End-Use...

  20. 7 CFR 782.12 - Filing FSA-750, End-Use Certificate for Wheat.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 7 Agriculture 7 2012-01-01 2012-01-01 false Filing FSA-750, End-Use Certificate for Wheat. 782.12 Section 782.12 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS END-USE CERTIFICATE PROGRAM Implementation of the End-Use...

  1. A Deep Neural Network Model for Rainfall Estimation UsingPolarimetric WSR-88DP Radar Observations

    NASA Astrophysics Data System (ADS)

    Tan, H.; Chandra, C. V.; Chen, H.

    2016-12-01

    Rainfall estimation based on radar measurements has been an important topic for a few decades. Generally, radar rainfall estimation is conducted through parametric algorisms such as reflectivity-rainfall relation (i.e., Z-R relation). On the other hand, neural networks are developed for ground rainfall estimation based on radar measurements. This nonparametric method, which takes into account of both radar observations and rainfall measurements from ground rain gauges, has been demonstrated successfully for rainfall rate estimation. However, the neural network-based rainfall estimation is limited in practice due to the model complexity and structure, data quality, as well as different rainfall microphysics. Recently, the deep learning approach has been introduced in pattern recognition and machine learning areas. Compared to traditional neural networks, the deep learning based methodologies have larger number of hidden layers and more complex structure for data representation. Through a hierarchical learning process, the high level structured information and knowledge can be extracted automatically from low level features of the data. In this paper, we introduce a novel deep neural network model for rainfall estimation based on ground polarimetric radar measurements .The model is designed to capture the complex abstractions of radar measurements at different levels using multiple layers feature identification and extraction. The abstractions at different levels can be used independently or fused with other data resource such as satellite-based rainfall products and/or topographic data to represent the rain characteristics at certain location. In particular, the WSR-88DP radar and rain gauge data collected in Dallas - Fort Worth Metroplex and Florida are used extensively to train the model, and for demonstration purposes. Quantitative evaluation of the deep neural network based rainfall products will also be presented, which is based on an independent rain gauge

  2. 42 CFR 423.750 - Types of intermediate sanctions and civil money penalties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Types of intermediate sanctions and civil money... BENEFIT Intermediate Sanctions § 423.750 Types of intermediate sanctions and civil money penalties. (a... Medicare beneficiaries by a Part D plan sponsor. (b) CMS may impose civil money penalties as specified in...

  3. 42 CFR 423.750 - Types of intermediate sanctions and civil money penalties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Types of intermediate sanctions and civil money... BENEFIT Intermediate Sanctions § 423.750 Types of intermediate sanctions and civil money penalties. (a... Medicare beneficiaries by a Part D plan sponsor. (b) CMS may impose civil money penalties as specified in...

  4. 750 GeV diphoton resonance and inflation

    NASA Astrophysics Data System (ADS)

    Hamada, Yuta; Noumi, Toshifumi; Shiu, Gary; Sun, Sichun

    2016-06-01

    We study the possibility of a heavy scalar or pseudoscalar in TeV-scale beyond the Standard Model scenarios being the inflaton of the early universe in light of the recent O (750 ) GeV diphoton excess at the LHC. We consider a scenario in which the new scalar or pseudoscalar couples to the Standard Model gauge bosons at the loop level through new massive Standard Model charged vectorlike fermions with or without dark fermions. We calculate the renormalization group running of both the Standard Model and the new scalar couplings, and present two different models that are perturbative, with a stabilized vacuum up to near the Planck scale. Thus, the Standard Model Higgs and this possible new resonance may still preserve the minimalist features of Higgs inflation.

  5. Implications of the 750 GeV γγ Resonance as a Case Study for the International Linear Collider

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fujii, Keisuke; Grojean, Christophe; Peskin, Michael E.

    If the γγ resonance at 750 GeV suggested by 2015 LHC data turns out to be a real effect, what are the implications for the physics case and upgrade path of the International Linear Collider? Whether or not the resonance is confirmed, this question provides an interesting case study testing the robustness of the ILC physics case. In this note, we address this question with two points: (1) Almost all models proposed for the new 750 GeV particle require additional new particles with electroweak couplings. The key elements of the 500 GeV ILC physics program - precision measurements of themore » Higgs boson, the top quark, and 4-fermion interactions - will powerfully discriminate among these models. This information will be important in conjunction with new LHC data, or alone, if the new particles accompanying the 750 GeV resonance are beyond the mass reach of the LHC. (2) Over a longer term, the energy upgrade of the ILC to 1 TeV already discussed in the ILC TDR will enable experiments in γγ and e +e - collisions to directly produce and study the 750 GeV particle from these unique initial states.« less

  6. 2. OVERVIEW OF STRUCTURES S748, S749 AND S750, FACING NORTHEAST ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    2. OVERVIEW OF STRUCTURES S748, S749 AND S750, FACING NORTHEAST (From West End of Tank Farm) - U.S. Naval Base, Pearl Harbor, Bulk Fuel Storage Tank Type, Middle Tank Farm, east of North Road, Pearl City, Honolulu County, HI

  7. 42 CFR 422.750 - Types of intermediate sanctions and civil money penalties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Types of intermediate sanctions and civil money... § 422.750 Types of intermediate sanctions and civil money penalties. (a) The following intermediate... organization. (b) CMS may impose civil money penalties as specified in 422.760. [72 FR 68725, Dec. 5, 2007, as...

  8. 42 CFR 422.750 - Types of intermediate sanctions and civil money penalties.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Types of intermediate sanctions and civil money... § 422.750 Types of intermediate sanctions and civil money penalties. (a) The following intermediate... organization. (b) CMS may impose civil money penalties as specified in 422.760. [72 FR 68725, Dec. 5, 2007, as...

  9. Anti-nociceptive and anti-inflammatory effects of Withania somnifera root in fructose fed male rats.

    PubMed

    Shahraki, Mohammad Reza; Samadi Noshahr, Zahra; Ahmadvand, Hassan; Nakhaie, Alireza

    2016-06-01

    Insulin resistance is a metabolic disorder which affects the diabetes mellitus pathophysiology and alters the cell excitability. This study has been designed to evaluate the anti-nociceptive and anti-inflammatory effects of chronic administration of Withania somnifera root (WSR) in fructose drinking water rats. An experiment was carried out on 48 Wistar-Albino male rats, weighting 200±30 g, which were divided into six groups (n=8): control group (C), control morphine (CM), W. somnifera group (WS) which received WSR (62.5 mg/g diet), W. somnifera naloxone group (WSN) which received WSR and naloxone, fructose (F) group which received fructose drinking water and FWS group which received fructose-enriched drinking water and WSR during the trial period. A biphasic pain response was induced after intraplantar injection of formalin (50 μL, 1%). Pain behavior was measured using Dubuisson methods. The obtained data were analyzed by SPSS software V. 18, using ANOVA and Tukey test. Results were expressed as mean±SD. Statistical differences were considered significant at p<0.05. The results showed that the insulin resistance index, blood sugar, insulin, IL-6, TNF-α, and acute and chronic pain score in the F group were significantly increased in comparison with the control group, but these parameters in the FWS group were significantly decreased compared with the F group (p<0.001). Our findings indicated that chronic oral administration of WSR has analgesic and anti-inflammatory effects in fructose drinking water rats and causes improved insulin resistance index.

  10. Levofloxacin 750-mg for 5 days for the treatment of hospitalized Fine Risk Class III/IV community-acquired pneumonia patients.

    PubMed

    Shorr, Andrew F; Khashab, Mohammed M; Xiang, Jim X; Tennenberg, Alan M; Kahn, James B

    2006-12-01

    The efficacy and safety of 750-mg, 5-day levofloxacin was recently shown to be comparable to 500-mg, 10-day levofloxacin in a randomized, double-blind, multicentre clinical trial for mild-to-severe community-acquired pneumonia (CAP). This subgroup analysis attempted to compare the safety and efficacy of a short-course levofloxacin regimen with traditional levofloxacin dosing for PSI Class III/IV patients. This retrospective, subgroup analysis focused on Pneumonia Severity Index Class III and IV patients enrolled in the study. Measurements included clinical and microbiological success rates, adverse events, and symptom resolution by day 3 of therapy. Of the 528 patients in the ITT population, 219 (41.5%) were categorized as PSI Class III/IV and included in this analysis. Among the clinically evaluable patients, 90.8% (69/76) of patients treated with the 750-mg regimen achieved clinical success, compared with 85.5% (71/83) treated with 500-mg levofloxacin (95% CI,-15.9 to 5.4). Eradication rates in the microbiologically evaluable population were comparable for the 750- and 500-mg regimens (88.9% vs 87.5%, respectively; 95% CI,-18.3 to 15.6). Both regimens were well tolerated and had comparable safety profiles. A greater proportion of patients in the 750-mg treatment group experienced resolution of fever (48.4% vs 34.0%; P=.046) and purulent sputum (48.4% vs 27.5%; P=.007) by day 3 of therapy. The 750-mg, 5-day levofloxacin course achieved comparable clinical and microbiologic efficacy to the 500-mg, 10-day regimen. By day 3 of therapy, a greater proportion of patients in the 750-mg group had objective and subjective resolution of fever. Further research is needed to determine the economic significance of short-course levofloxacin therapy.

  11. 42 CFR 422.750 - Types of intermediate sanctions and civil money penalties.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 42 Public Health 3 2013-10-01 2013-10-01 false Types of intermediate sanctions and civil money... Intermediate Sanctions § 422.750 Types of intermediate sanctions and civil money penalties. (a) The following... organization. (b) CMS may impose civil money penalties as specified in 422.760. [72 FR 68725, Dec. 5, 2007, as...

  12. 42 CFR 423.750 - Types of intermediate sanctions and civil money penalties.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 3 2011-10-01 2011-10-01 false Types of intermediate sanctions and civil money... Intermediate Sanctions § 423.750 Types of intermediate sanctions and civil money penalties. (a) The following... by a Part D plan sponsor. (b) CMS may impose civil money penalties as specified in 423.760. [72 FR...

  13. 42 CFR 422.750 - Types of intermediate sanctions and civil money penalties.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 42 Public Health 3 2014-10-01 2014-10-01 false Types of intermediate sanctions and civil money... Intermediate Sanctions § 422.750 Types of intermediate sanctions and civil money penalties. (a) The following... organization. (b) CMS may impose civil money penalties as specified in 422.760. [72 FR 68725, Dec. 5, 2007, as...

  14. 40 CFR 60.750 - Applicability, designation of affected facility, and delegation of authority.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Standards of Performance for Municipal Solid Waste Landfills § 60.750 Applicability, designation of affected facility, and delegation of authority. (a) The provisions of this subpart apply to each municipal solid waste landfill that commenced construction, reconstruction or modification on or after May 30, 1991...

  15. 40 CFR 60.750 - Applicability, designation of affected facility, and delegation of authority.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Standards of Performance for Municipal Solid Waste Landfills § 60.750 Applicability, designation of affected facility, and delegation of authority. (a) The provisions of this subpart apply to each municipal solid waste landfill that commenced construction, reconstruction or modification on or after May 30, 1991...

  16. SU-E-I-22: A Comprehensive Investigation of Noise Variations Between the GE Discovery CT750 HD and GE LightSpeed VCT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bache, S; Loyer, E; Stauduhar, P

    2015-06-15

    Purpose: To quantify and compare the noise properties between two GE CT models-the Discovery CT750 HD (aka HD750) and LightSpeed VCT, with the overall goal of assessing the impact in clinical diagnostic practice. Methods: Daily QC data from a fleet of 9 CT scanners currently in clinical use were investigated – 5 HD750 and 4 VCT (over 600 total acquisitions for each scanner). A standard GE QC phantom was scanned daily using two sets of scan parameters with each scanner over 1 year. Water CT number and standard deviation were recorded from the image of water section of the QCmore » phantom. The standard GE QC scan parameters (Pitch = 0.516, 120kVp, 0.4s, 335mA, Small Body SFOV, 5mm thickness) and an in-house developed protocol (Axial, 120kVp, 1.0s, 240mA, Head SFOV, 5mm thickness) were used, with Standard reconstruction algorithm. Noise was measured as the standard deviation in the center of the water phantom image. Inter-model noise distributions and tube output in mR/mAs were compared to assess any relative differences in noise properties. Results: With the in-house protocols, average noise for the five HD750 scanners was ∼9% higher than the VCT scanners (5.8 vs 5.3). For the GE QC protocol, average noise with the HD750 scanners was ∼11% higher than with the VCT scanners (4.8 vs 4.3). This discrepancy in noise between the two models was found despite the tube output in mR/mAs being comparable with the HD750 scanners only having ∼4% lower output (8.0 vs 8.3 mR/mAs). Conclusion: Using identical scan protocols, average noise in images from the HD750 group was higher than that from the VCT group. This confirms feedback from an institutional radiologist’s feedback regarding grainier patient images from HD750 scanners. Further investigation is warranted to assess the noise texture and distribution, as well as clinical impact.« less

  17. 30 CFR 750.21 - Coal extraction incidental to the extraction of other minerals.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 3 2013-07-01 2013-07-01 false Coal extraction incidental to the extraction of... ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN LANDS PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.21 Coal extraction incidental to the extraction of other minerals...

  18. 30 CFR 750.21 - Coal extraction incidental to the extraction of other minerals.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 3 2011-07-01 2011-07-01 false Coal extraction incidental to the extraction of... ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN LANDS PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.21 Coal extraction incidental to the extraction of other minerals...

  19. 30 CFR 750.21 - Coal extraction incidental to the extraction of other minerals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Coal extraction incidental to the extraction of... ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN LANDS PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.21 Coal extraction incidental to the extraction of other minerals...

  20. 30 CFR 750.21 - Coal extraction incidental to the extraction of other minerals.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 3 2014-07-01 2014-07-01 false Coal extraction incidental to the extraction of... ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN LANDS PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.21 Coal extraction incidental to the extraction of other minerals...

  1. 30 CFR 750.21 - Coal extraction incidental to the extraction of other minerals.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 3 2012-07-01 2012-07-01 false Coal extraction incidental to the extraction of... ENFORCEMENT, DEPARTMENT OF THE INTERIOR INDIAN LANDS PROGRAM REQUIREMENTS FOR SURFACE COAL MINING AND RECLAMATION OPERATIONS ON INDIAN LANDS § 750.21 Coal extraction incidental to the extraction of other minerals...

  2. Multipacting optimization of a 750 MHz rf dipole

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delayen, Jean R.; Castillo, Alejandro

    2014-12-01

    Crab crossing schemes have been proposed to re-instate luminosity degradation due to crossing angles at the interaction points in next generation colliders to avoid the use of sharp bending magnets and their resulting large synchrotron radiation generation, highly undessirable in the detector region. The rf dipole has been considered for a different set of applications in several machines, both rings and linear colliders. We present in this paper a study of the effects on the multipacting levels and location depending on geometrical variations on the design for a crabbing/deflecting application in a high current (3/0.5 A), high repetition (750 MHz)more » electron/proton collider, as a matter to provide a comparison point for similar applications of rf dipoles.« less

  3. 23 CFR 750.104 - Signs that may not be permitted in protected areas.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 23 Highways 1 2011-04-01 2011-04-01 false Signs that may not be permitted in protected areas. 750... permitted in protected areas. Erection or maintenance of the following signs may not be permitted in protected areas: (a) Signs advertising activities that are illegal under State or Federal laws or...

  4. Patient stratification in the management of acute bacterial exacerbation of chronic bronchitis: the role of levofloxacin 750 mg.

    PubMed

    Martinez, F J; Grossman, R F; Zadeikis, N; Fisher, A C; Walker, K; Ambruzs, M E; Tennenberg, A M

    2005-06-01

    This is the first prospective clinical trial in which patients with acute bacterial exacerbation of chronic bronchitis have been stratified by degree of underlying illness. Uncomplicated patients were randomised to levofloxacin 750 mg once daily (q.d.) for 3 days or azithromycin q.d. for 5 days. Complicated patients were randomised to levofloxacin 750 mg q.d. for 5 days or amoxicillin 875 mg/clavulanate 125 mg twice daily for 10 days. Regardless of therapy, complicated patients demonstrated lower clinical and microbiological success than uncomplicated patients. Clinical success for clinically evaluable patients was similar for levofloxacin and azithromycin (93.0 versus 90.1%, respectively), and levofloxacin and amoxicillin/clavulanate (79.2 versus 81.7%, respectively). For microbiologically evaluable patients, clinical response to levofloxacin for 3 days was superior to azithromycin for 5 days (96.3 versus 87.4%, respectively), and levofloxacin for 5 days was similar to amoxicillin/clavulanate for 10 days (81.4 versus 80.9%, respectively). Microbiological eradication was superior for levofloxacin for 3 days compared with azithromycin for 5 days (93.8 versus 82.8%, respectively), and similar for levofloxacin and amoxicillin/clavulanate for 10 days (81.4 versus 79.8%, respectively). In conclusion, levofloxacin 750 mg for 3 days was comparable to azithromycin for 5 days for uncomplicated patients with acute bacterial exacerbation of chronic bronchitis, while 5 days of 750 mg levofloxacin was comparable to 10 days of amoxicillin/clavulanate for complicated acute bacterial exacerbation of chronic bronchitis.

  5. 23 CFR 750.104 - Signs that may not be permitted in protected areas.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Advertising Adjacent to the Interstate System Under the 1958 Bonus Program § 750.104 Signs that may not be... protected areas: (a) Signs advertising activities that are illegal under State or Federal laws or regulations in effect at the location of such signs or at the location of such activities. (b) Obsolete signs...

  6. Validation of TRMM Precipitation Radar Through Comparison of its Multi-Year Measurements to Ground-Based Radar

    NASA Technical Reports Server (NTRS)

    Liao, Liang; Meneghini, Robert

    2010-01-01

    A procedure to accurately resample spaceborne and ground-based radar data is described, and then applied to the measurements taken from the Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR) and the ground-based Weather Surveillance Radar-1988 Doppler (WSR-88D or WSR) for the validation of the PR measurements and estimates. Through comparisons with the well-calibrated, non-attenuated WSR at Melbourne, Florida for the period 1998-2007, the calibration of the Precipitation Radar (PR) aboard the TRMM satellite is checked using measurements near the storm top. Analysis of the results indicates that the PR, after taking into account differences in radar reflectivity factors between the PR and WSR, has a small positive bias of 0.8 dB relative to the WSR, implying a soundness of the PR calibration in view of the uncertainties involved in the comparisons. Comparisons between the PR and WSR reflectivities are also made near the surface for evaluation of the attenuation-correction procedures used in the PR algorithms. It is found that the PR attenuation is accurately corrected in stratiform rain but is underestimated in convective rain, particularly in heavy rain. Tests of the PR estimates of rainfall rate are conducted through comparisons in the overlap area between the TRMM overpass and WSR scan. Analyses of the data are made both on a conditional basis, in which the instantaneous rain rates are compared only at those pixels where both the PR and WSR detect rain, and an unconditional basis, in which the area-averaged rain rates are estimated independently for the PR and WSR. Results of the conditional rain comparisons show that the PR-derived rain is about 9% greater and 19% less than the WSR estimates for stratiform and convective storms, respectively. Overall, the PR tends to underestimate the conditional mean rain rate by 8% for all rain categories, a finding that conforms to the results of the area-averaged rain (unconditional) comparisons.

  7. Effect of cold drawing ratio on γ′ precipitation in Inconel X-750

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ha, Jeong Won; Research and Development Center, KOS Limited, Yangsan 626-230; Seong, Baek Seok

    2014-10-15

    Inconel X-750 is a Ni-based precipitation-hardened superalloy having large tensile and fracture strengths. In the study, X-750 wires were cold drawn to different extents. Small angle neutron scattering was employed to quantitatively measure the size and volume fraction of the γ′ phase as a function of the cold drawing ratio (DR) and aging temperature. The presence and size of γ′ precipitates were confirmed by transmission electron microscopy. The drawing ratio had an important effect on the volume fraction of the γ′ precipitates. However, the size of the precipitates was independent on the drawing ratio. The specimen with the minimum drawingmore » ratio (DR0) produced the largest volume fraction of γ′ as compared with large drawing ratio (DR) specimens such as DR17 and DR42. The small volume fraction of the γ′ phase for a sizeable drawing ratio was associated with the large amount of nucleation sites for secondary carbides, M{sub 23}C{sub 6}, and the fast diffusion path, i.e., dislocation, needed to form M{sub 23}C{sub 6}. A Cr depletion zone around the secondary carbides raised the solubility of γ′. Therefore, the significant drawing ratio contributing to the large volume fraction of the secondary carbides decreased the volume fraction of the γ′ precipitates in Inconel X-750. - Highlights: • The volume fraction of secondary carbides increased with the drawing ratio. • The volume fraction of γ′ decreased as the drawing ratio increased. • The drawing ratio affected the γ′ volume fraction with no variation of the γ' size. • The volume fraction of γ′ was affected by the secondary carbide volume fraction.« less

  8. Preparation and in-vivo pharmacokinetic study of a novel extended release compression coated tablets of fenoterol hydrobromide.

    PubMed

    Elshafeey, Ahmed H; Sami, Elshaimaa I

    2008-01-01

    The aim of this study was to formulate extended release compression coated core tablets of fenoterol hydrobromide, a selective beta(2) adrenergic receptor agonist, in an attempt to prevent nocturnal asthma. Two hydrophilic polymers viz Kollidon SR, Polyox WSR 303 and a hydrophobic one (Precirol ATO5) were employed. Compression coated tablets were formulated by preparing a core tablet containing 7.5 mg drug and various amounts of polymer and Emcompress then compressed coated with the same polymeric materials. For comparison purpose different matrix tablets were also prepared employing the same polymers. In-vitro release studies were carried out at different pH (1.2 and 6.8). Pharmacokinetics of extended release tablets as well as commercially available immediate release tablets (Berotec) were studied after oral administration to beagle dogs using a new developed LC-MS/MS method with a lower limit of quantification of 1 ng/ml. Fenoterol release from compression coated tablets was significantly lower than matrix tablets. The mechanism of release was changed with the nature and content of polymer. The release pattern of drug from F16 containing 40 mg Kollidon SR divided in the core tablet (15 mg) and the rest in the compressed coat (25 mg) showed a typical zero order release kinetic that could extend drug release >10 h and reasonable time for 75% to be released (t(75)) (8.92 h). When compared to immediate release Berotec tablet the MRT was significantly extended from 7.03 +/- 0.76 to 10.93 +/- 1.25 h (P < 0.001) and HVD(t 50%Cmax) was also significantly extended from 2.71 +/- 0.68 to 6.81 +/- 0.67 h with expected prevention of nocturnal asthma.

  9. Lymphoid irradiation in intractable rheumatoid arthritis. A double-blind, randomized study comparing 750-rad treatment with 2,000-rad treatment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hanly, J.G.; Hassan, J.; Moriarty, M.

    1986-01-01

    Twenty patients with intractable rheumatoid arthritis were treated with 750-rad or 2,000-rad lymphoid irradiation in a randomized double-blind comparative study. Over a 12-month followup period, there was a significant improvement in 4 of 7 and 6 of 7 standard parameters of disease activity following treatment with 750 rads and 2,000 rads, respectively. Transient, short-term toxicity was less frequent with the lower dose. In both groups, there was a sustained peripheral blood lymphopenia, a selective depletion of T helper (Leu-3a+) lymphocytes, and reduced in vitro mitogen responses. These changes did not occur, however, in synovial fluid. These results suggest that 750-radmore » lymphoid irradiation is as effective as, but less toxic than, that with 2,000 rads in the management of patients with intractable rheumatoid arthritis.« less

  10. A 750 GeV messenger of dark conformal symmetry breaking

    DOE PAGES

    Davoudiasl, Hooman; Zhang, Cen

    2016-03-03

    The tentative hints for a diphoton resonance at a mass of ~750 GeV from the ATLAS and CMS experiments at the LHC may be interpreted as first contact with a “dark” sector with a spontaneously broken conformal symmetry. The implied TeV scale of the dark sector may be motivated by the interaction strength required to accommodate a viable thermal relic dark matter (DM) candidate. We model the conformal dynamics using a Randall-Sundrum-type five-dimensional geometry whose IR boundary is identified with the dynamics of the composite dark sector, while the Standard Model (SM) matter content resides on the UV boundary, correspondingmore » to “elementary” fields. We allow the gauge fields to reside in the five-dimensional bulk, which can be minimally chosen to be SU(3)c×U(1)Y. The “dark” radion is identified as the putative 750 GeV resonance. Heavy vectorlike fermions, often invoked to explain the diphoton excess, are not explicitly present in our model and are not predicted to appear in the spectrum of TeV scale states. Our minimal setup favors scalar DM of O(TeV) mass. A generic expectation in this scenario, suggested by DM considerations, is the appearance of vector bosons at ~ few TeV, corresponding to the gluon and hypercharge Kaluza-Klein (KK) modes that couple to UV boundary states with strengths that are suppressed uniformly compared to their SM values. Furthermore, our analysis suggests that these KK modes could be within the reach of the LHC in the coming years.« less

  11. A 750 GeV messenger of dark conformal symmetry breaking

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Davoudiasl, Hooman; Zhang, Cen

    The tentative hints for a diphoton resonance at a mass of ~750 GeV from the ATLAS and CMS experiments at the LHC may be interpreted as first contact with a “dark” sector with a spontaneously broken conformal symmetry. The implied TeV scale of the dark sector may be motivated by the interaction strength required to accommodate a viable thermal relic dark matter (DM) candidate. We model the conformal dynamics using a Randall-Sundrum-type five-dimensional geometry whose IR boundary is identified with the dynamics of the composite dark sector, while the Standard Model (SM) matter content resides on the UV boundary, correspondingmore » to “elementary” fields. We allow the gauge fields to reside in the five-dimensional bulk, which can be minimally chosen to be SU(3)c×U(1)Y. The “dark” radion is identified as the putative 750 GeV resonance. Heavy vectorlike fermions, often invoked to explain the diphoton excess, are not explicitly present in our model and are not predicted to appear in the spectrum of TeV scale states. Our minimal setup favors scalar DM of O(TeV) mass. A generic expectation in this scenario, suggested by DM considerations, is the appearance of vector bosons at ~ few TeV, corresponding to the gluon and hypercharge Kaluza-Klein (KK) modes that couple to UV boundary states with strengths that are suppressed uniformly compared to their SM values. Furthermore, our analysis suggests that these KK modes could be within the reach of the LHC in the coming years.« less

  12. Preparation of delayed release tablet dosage forms by compression coating: effect of coating material on theophylline release.

    PubMed

    El-Malah, Yasser; Nazzal, Sami

    2010-06-01

    In this study, compression-coated tablets were prepared and examined by real-time swelling/erosion analysis and dissolution studies. Of the coating materials, PVP showed no swelling behavior and had no impact on theophylline release. Polyox(®) exhibited swelling behavior of an entangled polymer, which was reflected in its > 14-hour delayed-release profile. Hydroxypropyl methylcellulose (HPMC), which revealed the characteristics of a disentangled polymer, caused a 2-h delay in theophylline release. Based on preliminary texture analysis data, Polyox(®)/PVP blends were used as coating materials to manipulate the onset of drug release from the compression-coated tablets. Of the blends, at a 1:1 ratio, for example, resulted in a burst release after 10 h, which demonstrated the feasibility of preparing delayed release dosage forms by compression coating. Furthermore, it was feasible to predict the dissolution behavior of polymers from their swelling/erosion data, which were generated from texture analysis.

  13. Effects of the aging temperature and stress relaxation conditions on γ‧ precipitation in Inconel X-750

    NASA Astrophysics Data System (ADS)

    Ha, Jeong Won; Seong, Baek Seok; Jeong, Hi Won; Choi, Yoon Suk; Kang, Namhyun

    2015-02-01

    Inconel X-750 is a Ni-based precipitation-hardened superalloy typically used in springs designed for high-temperature applications such as the hold-down springs in nuclear power plants. γ‧ is a major precipitate in X-750 alloys which affects the strength, creep resistance, and stress relaxation properties of the spring. In this study, a solution-treated X-750 wire coiled into a spring was used that was aged at various temperatures and submitted to stress relaxation tests with and without loading. Small angle neutron scattering was employed to quantify the size and volume fraction of γ‧ phase in the springs as a function of the aging temperature and the application of a load during stress relaxation. The volume fraction of γ‧ precipitates increased in the specimen aged at 732 °C following stress relaxation at 500 °C for 300 h. However, the mean size of the precipitates in the samples was not affected by stress relaxation. The specimen aged at the lower temperature (620 °C) contained a smaller γ‧ volume fraction and gained a smaller fraction of γ‧ during stress relaxation compared with the sample aged at the higher temperature (732 °C). The smaller increase in the γ‧ volume fraction for the sample aged at 620 °C was associated with a larger increase in the M23C6 secondary carbide content during relaxation. The Cr depletion zone around the secondary carbides raises the solubility of γ‧ thereby decreasing the volume fraction of γ‧ precipitates in Inconel X-750. In terms of stress relaxation, a larger increase in the γ‧ volume fraction was measured with loading rather than without. This is probably associated with the dislocation accumulation generated under loading that facilitate the nucleation and growth of heterogeneous γ‧ phase due to enhanced diffusion.

  14. Safety and efficacy of levofloxacin 750 mg for 2 weeks or 3 weeks compared with levofloxacin 500 mg for 4 weeks in treating chronic bacterial prostatitis.

    PubMed

    Paglia, Margaret; Peterson, Janet; Fisher, Alan C; Qin, Zhihai; Nicholson, Susan C; Kahn, James B

    2010-06-01

    To compare the safety and efficacy of levofloxacin 750 mg QD for 2 weeks or levofloxacin 750 mg QD for 3 weeks to levofloxacin 500 mg QD for 4 weeks in treating chronic bacterial prostatitis (CBP). This was a randomized, multicenter, double-blind, noninferiority study. The primary efficacy end point was investigator assessment of clinical success in the modified intent-to-treat (mITT) population at post-therapy. National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) scores were utilized to evaluate subject-reported responses post-therapy. A total of 241 subjects were enrolled. At post-therapy (test of cure [TOC]), clinical success rates for levofloxacin-treated subjects (750 mg QD for 3 weeks [64.9%, 48/74]) were noninferior to 500 mg QD for 4 weeks (69.3%, 52/75: 95% CI, -19.5%, 10.6%). Success rates with levofloxacin 750 mg QD for 2 weeks (63.0%, 46/73) were not noninferior to therapy with levofloxacin 500 mg QD for 4 weeks (95% CI, -21.5%, 8.9%) at TOC. At 3 and 6 months post-therapy, clinical success rates were clinically higher for the 500-mg, 4-week treatment group, and statistical analysis demonstrated both groups were not noninferior to standard therapy with levofloxacin 500 mg (95% CI, -32.5%, -0.6% for both 750-mg groups at 6 months). NIH-CPSI scores showed similar trends. Overall, adverse event (AE) rates were similar for the three treatment groups; however, discontinuation of therapy due to AEs was higher with the 750-mg dose (p = 0.02, and p = 0.13 for 750 mg, 2 weeks and 750 mg, 3 weeks versus 500 mg for 4 weeks, respectively). The main limitation of this study was that no bacterial cultures were required. Higher doses for shorter durations were determined to be no worse than standard therapy with levofloxacin 500 mg for a longer duration at the TOC visit. However, at the 6-month follow-up visit, the levofloxacin 750-mg dose administered for either 2 weeks or 3 weeks was inferior to the standard therapy, suggesting that a longer

  15. 750 GeV diphoton resonance, 125 GeV Higgs and muon g - 2 anomaly in deflected anomaly mediation SUSY breaking scenarios

    NASA Astrophysics Data System (ADS)

    Wang, Fei; Wu, Lei; Yang, Jin Min; Zhang, Mengchao

    2016-08-01

    We propose to interpret the 750 GeV diphoton excess in deflected anomaly mediation supersymmetry breaking scenarios, which can naturally predict couplings between a singlet field and vector-like messengers. The CP-even scalar component (S) of the singlet field can serve as the 750 GeV resonance. The messenger scale, which is of order the gravitino scale, can be as light as Fϕ ∼ O (10) TeV when the messenger species NF and the deflection parameter d are moderately large. Such messengers can induce the large loop decay process S → γγ. Our results show that such a scenario can successfully accommodate the 125 GeV Higgs boson, the 750 GeV diphoton excess and the muon g - 2 without conflicting with the LHC constraints. We also comment on the possible explanations in the gauge mediation supersymmetry breaking scenario.

  16. Effects of N loading rate on CH4 and N2O emissions during cultivation and fallow periods from forage rice fields fertilized with liquid cattle waste.

    PubMed

    Riya, S; Zhou, S; Kobara, Y; Sagehashi, M; Terada, A; Hosomi, M

    2015-09-15

    The use of liquid cattle waste (LCW) as a fertilizer for forage rice is important for material recycling because it can promote biomass production, and reduce the use of chemical fertilizer. Meanwhile, increase in emission of greenhouse gases (GHGs), especially CH4 and N2O would be concerned. We conducted a field study to determine the optimum loading rate of LCW as N to promote forage rice growth with lower GHG emissions. The LCW was applied to forage rice fields, N100, N250, N500, and N750, at four different N loading rates of 107, 258, 522, and 786 kg N ha(-1), respectively, including 50 kg N ha(-1) of basal chemical fertilizer. The above-ground biomass yields increased 14.6-18.5 t ha(-1) with increases in N loading rates. During the cultivation period, both the CH4 and N2O fluxes increased with increases in LCW loading rates. In the treatments of N100, N250, N500, and N750, the cumulative CH4 emissions during the entire period, including cultivation and fallow period were 29.6, 18.1, 54.4, and 67.5 kg C ha(-1), respectively, whereas those of N2O were -0.15, -0.02, 1.49, and 5.82 kg N ha(-1), respectively. Considering the greenhouse gas emissions and above-ground biomass, the yield-scaled CO2-equivalents (CO2-eqs) were 66.3, 35.9, 161, and 272 kg CO2 t(-1) for N100, N250, N500, and N750, respectively. These results suggest that N250 is the most appropriate LCW loading rate for promoting forage rice production with lower GHG emissions. Copyright © 2015 Elsevier Ltd. All rights reserved.

  17. Efficiency of the DOMUS 750 vertical-axis wind turbine

    NASA Astrophysics Data System (ADS)

    Hallock, Kyle; Rasch, Tyler; Ju, Guoqiang; Alonso-Marroquin, Fernando

    2017-06-01

    The aim of this paper is to present some preliminary results on the efficiency of a wind turbine for an off-grid housing unit. To generate power, the unit uses a photovoltaic solar array and a vertical-axis wind turbine (VAWT). The existing VAWT was analysed to improve efficiency and increase power generation. There were found to be two main sources of inefficiency: 1. the 750W DC epicyclic generator performed poorly in low winds, and 2. the turbine blades wobbled, allowing for energy loss due to off-axis rotation. A 12V DC permanent magnet alternator was chosen that met the power requirements of the housing unit and would generate power at lower wind speeds. A support bracket was designed to prevent the turbine blades from wobbling.

  18. Surface chemistry, microstructure and friction properties of some ferrous-base metallic glasses at temperatures to 750 C

    NASA Technical Reports Server (NTRS)

    Miyoshi, K.; Buckley, D. H.

    1982-01-01

    X-ray photoelectron spectroscopy analysis, transmission electron microscopy, diffraction studies, and sliding friction experiments were conducted with ferrous-base metallic glasses in sliding contact with aluminum oxide at temperatures from room to 750 C in a vacuum of 30 nPa. The results indicate that there is a significant temperature influence on the friction properties, surface chemistry, and microstructure of metallic glasses. The relative concentrations of the various constituents at the surface of the sputtered specimens were very different from the normal bulk compositions. Contaminants can come from the bulk of the material to the surface upon heating and impart boric oxide and silicon oxide at 350 C and boron nitride above 500 C. The coefficient of friction increased with increasing temperature to 350 C. Above 500 C the coefficient of friction decreased rapidly. The segregation of contaminants may be responsible for the friction behavior.

  19. Comparisons of percentage body fat, body mass index, waist circumference, and waist-stature ratio in adults.

    PubMed

    Flegal, Katherine M; Shepherd, John A; Looker, Anne C; Graubard, Barry I; Borrud, Lori G; Ogden, Cynthia L; Harris, Tamara B; Everhart, James E; Schenker, Nathaniel

    2009-02-01

    Body mass index (BMI), waist circumference (WC), and the waist-stature ratio (WSR) are considered to be possible proxies for adiposity. The objective was to investigate the relations between BMI, WC, WSR, and percentage body fat (measured by dual-energy X-ray absorptiometry) in adults in a large nationally representative US population sample from the National Health and Nutrition Examination Survey (NHANES). BMI, WC, and WSR were compared with percentage body fat in a sample of 12,901 adults. WC, WSR, and BMI were significantly more correlated with each other than with percentage body fat (P < 0.0001 for all sex-age groups). Percentage body fat tended to be significantly more correlated with WC than with BMI in men but significantly more correlated with BMI than with WC in women (P < 0.0001 except in the oldest age group). WSR tended to be slightly more correlated with percentage body fat than was WC. Percentile values of BMI, WC, and WSR are shown that correspond to percentiles of percentage body fat increments of 5 percentage points. More than 90% of the sample could be categorized to within one category of percentage body fat by each measure. BMI, WC, and WSR perform similarly as indicators of body fatness and are more closely related to each other than with percentage body fat. These variables may be an inaccurate measure of percentage body fat for an individual, but they correspond fairly well overall with percentage body fat within sex-age groups and distinguish categories of percentage body fat.

  20. Thermal-mechanical fatigue crack growth in Inconel X-750

    NASA Technical Reports Server (NTRS)

    Marchand, N.; Pelloux, R. M.

    1984-01-01

    Thermal-mechanical fatigue crack growth (TMFCG) was studied in a gamma-gamma' nickel base superalloy Inconel X-750 under controlled load amplitude in the temperature range from 300 to 650 C. In-phase (T sub max at sigma sub max), out-of-phase (T sub min at sigma sub max), and isothermal tests at 650 C were performed on single-edge notch bars under fully reversed cyclic conditions. A dc electrical potential method was used to measure crack length. The electrical potential response obtained for each cycle of a given wave form and R value yields information on crack closure and crack extension per cycle. The macroscopic crack growth rates are reported as a function of delta k and the relative magnitude of the TMFCG are discussed in the light of the potential drop information and of the fractographic observations.

  1. Pharmacokinetics/pharmacodynamics of levofloxacin 750 mg once daily in young women with acute uncomplicated pyelonephritis.

    PubMed

    Nicolle, Lindsay; Duckworth, Heather; Sitar, Dan; Bryski, Lisa; Harding, Godfrey; Zhanel, George

    2008-03-01

    This pilot study was undertaken to characterise the pharmacokinetics, pharmacodynamics and potential clinical efficacy of levofloxacin 750 mg once daily for 5 days for treatment of women with acute uncomplicated pyelonephritis. Four women diagnosed with acute pyelonephritis were enrolled. Following pre-therapy specimen collection, an initial oral dose of 750 mg levofloxacin was administered. The mean pharmacokinetic parameters for the first dose were: maximum serum concentration (C(max)) 12.5+/-4.7 mg/L (range 5.6-16.0mg/L) (fC(max) 8.8+/-3.3, where f indicates the levofloxacin free or non-protein-bound fraction), area under the serum concentration-time curve (AUC) 85.4+/-14.1 mgh/L (range 66.2-96.8 mgh/L) (fAUC 59.8+/-9.9) and serum half-life (t(1/2)) 6.7+/-0.5h. Mean urine concentrations were 88.0+/-100mg/L at the 0-3 h collection, 307+/-143 mg/L at 3-6 h, 170+/-107 mg/L at 6-12 h and 85+/-8 mg/L at 12-24 h. Mean levofloxacin serum pharmacodynamics for infecting Escherichia coli were: C(max)/minimum inhibitory concentration (MIC) 323+/-185(fC(max)/MIC 226+/-129); and AUC/MIC 2339+/-830(fAUC/MIC 1647+/-579). Mean urine levofloxacin concentration/MIC ratios were: 900+/-1389 for 0-3 h, 12100+/-4950 for 3-6 h, 5922+/-3912 for 6-12 h and 2233+/-1037 for 12-24 h. Levofloxacin eradicated E. coli from the urine by 3-6 h after the first dose. Levofloxacin 750 mg once daily for 5 days has pharmacodynamics that support further evaluation of this regimen for treatment of women with acute uncomplicated pyelonephritis.

  2. Soot and Spectral Radiation Modeling for a High-Pressure Turbulent Spray Flame

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ferreryo-Fernandez, Sebastian; Paul, Chandan; Sircar, Arpan

    Simulations are performed of a transient high-pressure turbulent n-dodecane spray flame under engine-relevant conditions. An unsteady RANS formulation is used, with detailed chemistry, a semi-empirical two-equation soot model, and a particle-based transported composition probability density function (PDF) method to account for unresolved turbulent fluctuations in composition and temperature. Results from the PDF model are compared with those from a locally well-stirred reactor (WSR) model to quantify the effects of turbulence-chemistry-soot interactions. Computed liquid and vapor penetration versus time, ignition delay, and flame lift-off height are in good agreement with experiment, and relatively small differences are seen between the WSR andmore » PDF models for these global quantities. Computed soot levels and spatial soot distributions from the WSR and PDF models show large differences, with PDF results being in better agreement with experimental measurements. An uncoupled photon Monte Carlo method with line-by-line spectral resolution is used to compute the spectral intensity distribution of the radiation leaving the flame. This provides new insight into the relative importance of molecular gas radiation versus soot radiation, and the importance of turbulent fluctuations on radiative heat transfer.« less

  3. 40 CFR Appendix A to Subpart A of... - Appendix A to Subpart A of Part 750

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Reply comments due 2 weeks after end of informal hearing (§ 750.4(b)) 127 ... proceedings. In drawing up this third column, we have assumed that 60 days will be allowed for the submission of main comments; that the legislative phase of the informal hearing will take two weeks, and that...

  4. 40 CFR Appendix A to Subpart A of... - Appendix A to Subpart A of Part 750

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Reply comments due 2 weeks after end of informal hearing (§ 750.4(b)) 127 ... proceedings. In drawing up this third column, we have assumed that 60 days will be allowed for the submission of main comments; that the legislative phase of the informal hearing will take two weeks, and that...

  5. ON THE IMPACT OF SUPER RESOLUTION WSR-88D DOPPLER RADAR DATA ASSIMILATION ON HIGH RESOLUTION NUMERICAL MODEL FORECASTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chiswell, S

    2009-01-11

    Assimilation of radar velocity and precipitation fields into high-resolution model simulations can improve precipitation forecasts with decreased 'spin-up' time and improve short-term simulation of boundary layer winds (Benjamin, 2004 & 2007; Xiao, 2008) which is critical to improving plume transport forecasts. Accurate description of wind and turbulence fields is essential to useful atmospheric transport and dispersion results, and any improvement in the accuracy of these fields will make consequence assessment more valuable during both routine operation as well as potential emergency situations. During 2008, the United States National Weather Service (NWS) radars implemented a significant upgrade which increased the real-timemore » level II data resolution to 8 times their previous 'legacy' resolution, from 1 km range gate and 1.0 degree azimuthal resolution to 'super resolution' 250 m range gate and 0.5 degree azimuthal resolution (Fig 1). These radar observations provide reflectivity, velocity and returned power spectra measurements at a range of up to 300 km (460 km for reflectivity) at a frequency of 4-5 minutes and yield up to 13.5 million point observations per level in super-resolution mode. The migration of National Weather Service (NWS) WSR-88D radars to super resolution is expected to improve warning lead times by detecting small scale features sooner with increased reliability; however, current operational mesoscale model domains utilize grid spacing several times larger than the legacy data resolution, and therefore the added resolution of radar data is not fully exploited. The assimilation of super resolution reflectivity and velocity data into high resolution numerical weather model forecasts where grid spacing is comparable to the radar data resolution is investigated here to determine the impact of the improved data resolution on model predictions.« less

  6. Reactor performance of a 750 m(3) anaerobic digestion plant: varied substrate input conditions impacting methanogenic community.

    PubMed

    Wagner, Andreas Otto; Malin, Cornelia; Lins, Philipp; Gstraunthaler, Gudrun; Illmer, Paul

    2014-10-01

    A 750 m(3) anaerobic digester was studied over a half year period including a shift from good reactor performance to a reduced one. Various abiotic parameters like volatile fatty acids (VFA) (formic-, acetic-, propionic-, (iso-)butyric-, (iso-)valeric-, lactic acid), total C, total N, NH4 -N, and total proteins, as well as the organic matter content and dry mass were determined. In addition several process parameters such as temperature, pH, retention time and input of substrate and the concentrations of CH4, H2, CO2 and H2S within the reactor were monitored continuously. The present study aimed at the investigation of the abundance of acetogens and total cell numbers and the microbial methanogenic community as derived from PCR-dHPLC analysis in order to put it into context with the determined abiotic parameters. An influence of substrate quantity on the efficiency of the anaerobic digestion process was found as well as a shift from a hydrogenotrophic in times of good reactor performance towards an acetoclastic dominated methanogenic community in times of reduced reactor performance. After the change in substrate conditions it took the methano-archaeal community about 5-6 weeks to be affected but then changes occurred quickly. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Accessibility and Utilization of WSR-88D Radar Precipitation Data for Natural Resource Modeling Applications

    NASA Astrophysics Data System (ADS)

    Hardegree, S. P.

    2001-12-01

    The National Weather Service (NWS) operates approximately 160 WSR-88D radar-precipitation stations as part of a Next Generation Radar (NEXRAD) program that began implementation in 1992. Among other products, these radar sites provide spatial rainfall estimates, at approximately 4 km2 resolution (Stage 1, Level 3 data), with nominal coverage of 96% of the coterminous United States. Effective coverage is much less than this in a given radar domain depending upon storm type and topography. As the original intent of this network was to support operational objectives of the Departments of Defense, Transportation and Commerce, the production of these data have been optimized for detection and mitigation of severe weather events that might result in flooding, destruction of property and loss of life. The primary hydrologic application has been river and flood forecast modeling by 13 NWS River Forecast Centers (RFC). As each RFC is responsible for a large river drainage, data processing and quality control of these data are geared toward optimization over a relatively large spatial domain (>100,000 km2). Use of these data for other hydrologic and natural resource applications is hampered by a lack of tools for data access and manipulation. NWRC has modified decoding and geo-referencing programs to facilitate utilization of these data for other research and management applications. Stage 1, Level 3 Digital Precipitation Array (DPA) files were obtained for the Boise, Idaho radar location (CBX) for the period of January 1998 to December 2000. Nine rain-gauge locations in the Reynolds Creek Experimental Watershed and Snake River Birds of Prey National Conservation Area, south of Boise, were georeferenced relative to the CBX Hydrologic Rainfall Analysis Project (HRAP) grid. NEXRAD estimates of total cumulative rainfall at these sites averaged only 20% of that measured by the local gauge network. This underestimate was attributed in the most part to truncation of low intensity

  8. Comparison of the adverse event profiles of levofloxacin 500 mg and 750 mg in clinical trials for the treatment of respiratory infections.

    PubMed

    Khashab, Mohammed M; Xiang, Jim; Kahn, James B

    2006-10-01

    To compare safety data with levofloxacin 500 mg and 750 mg from clinical trials for the treatment of respiratory infections. We compared adverse event data for levofloxacin 500 mg and 750 mg from clinical trials in acute bacterial sinusitis, acute bacterial exacerbation of chronic bronchitis, and community-acquired pneumonia. Adverse events occurring after the initiation of therapy were classified as treatment-emergent adverse events (TEAE); drug-related adverse events (DRAE) were TEAE assessed by the clinical investigator as definitely/very likely or probably related to levofloxacin therapy. Overall, the safety profile of the two doses was similar but not identical. TEAE occurred in 49.0% (1601/3268) of those treated with 500 mg and in 45.5% (519/1141) of those treated with 750 mg (p = 0.042); the corresponding rates of DRAE were 7.6% (248/3268) and 8.0% (91/1141) (p = 0.699). There was no statistically significant difference in terms of overall TEAE and DRAE rates within each of the three infectious conditions, but there were in specific events, all of which are expected with levofloxacin therapy. The limitations of this analysis include that it utilized a subset of available safety data, that it includes data only from clinical trials, and that we report primarily on events occurring in > or = 2% of patients. Given similar adverse event profiles and the advantages of higher dose therapy, including shorter courses of therapy and potential impact on preventing resistance, clinicians should consider utilizing the 750 mg dose of levofloxacin when choosing between dosage strengths for treatment of indicated infections.

  9. Defining a Conceptual Topography of Word Concreteness: Clustering Properties of Emotion, Sensation, and Magnitude among 750 English Words

    PubMed Central

    Troche, Joshua; Crutch, Sebastian J.; Reilly, Jamie

    2017-01-01

    Cognitive science has a longstanding interest in the ways that people acquire and use abstract vs. concrete words (e.g., truth vs. piano). One dominant theory holds that abstract and concrete words are subserved by two parallel semantic systems. We recently proposed an alternative account of abstract-concrete word representation premised upon a unitary, high dimensional semantic space wherein word meaning is nested. We hypothesize that a range of cognitive and perceptual dimensions (e.g., emotion, time, space, color, size, visual form) bound this space, forming a conceptual topography. Here we report a normative study where we examined the clustering properties of a sample of English words (N = 750) spanning a spectrum of concreteness in a continuous manner from highly abstract to highly concrete. Participants (N = 328) rated each target word on a range of 14 cognitive dimensions (e.g., color, emotion, valence, polarity, motion, space). The dimensions reduced to three factors: Endogenous factor, Exogenous factor, and Magnitude factor. Concepts were plotted in a unified, multimodal space with concrete and abstract concepts along a continuous continuum. We discuss theoretical implications and practical applications of this dataset. These word norms are freely available for download and use at http://www.reilly-coglab.com/data/. PMID:29075224

  10. Defining a Conceptual Topography of Word Concreteness: Clustering Properties of Emotion, Sensation, and Magnitude among 750 English Words.

    PubMed

    Troche, Joshua; Crutch, Sebastian J; Reilly, Jamie

    2017-01-01

    Cognitive science has a longstanding interest in the ways that people acquire and use abstract vs. concrete words (e.g., truth vs. piano). One dominant theory holds that abstract and concrete words are subserved by two parallel semantic systems. We recently proposed an alternative account of abstract-concrete word representation premised upon a unitary, high dimensional semantic space wherein word meaning is nested. We hypothesize that a range of cognitive and perceptual dimensions (e.g., emotion, time, space, color, size, visual form) bound this space, forming a conceptual topography. Here we report a normative study where we examined the clustering properties of a sample of English words ( N = 750) spanning a spectrum of concreteness in a continuous manner from highly abstract to highly concrete. Participants ( N = 328) rated each target word on a range of 14 cognitive dimensions (e.g., color, emotion, valence, polarity, motion, space). The dimensions reduced to three factors: Endogenous factor, Exogenous factor, and Magnitude factor. Concepts were plotted in a unified, multimodal space with concrete and abstract concepts along a continuous continuum. We discuss theoretical implications and practical applications of this dataset. These word norms are freely available for download and use at http://www.reilly-coglab.com/data/.

  11. Prefrontal cortex expression of chromatin modifier genes in male WSP and WSR mice changes across ethanol dependence, withdrawal, and abstinence.

    PubMed

    Hashimoto, Joel G; Gavin, David P; Wiren, Kristine M; Crabbe, John C; Guizzetti, Marina

    2017-05-01

    Alcohol-use disorder (AUD) is a relapsing disorder associated with excessive ethanol consumption. Recent studies support the involvement of epigenetic mechanisms in the development of AUD. Studies carried out so far have focused on a few specific epigenetic modifications. The goal of this project was to investigate gene expression changes of epigenetic regulators that mediate a broad array of chromatin modifications after chronic alcohol exposure, chronic alcohol exposure followed by 8 h withdrawal, and chronic alcohol exposure followed by 21 days of abstinence in Withdrawal-Resistant (WSR) and Withdrawal Seizure-Prone (WSP) selected mouse lines. We found that chronic vapor exposure to highly intoxicating levels of ethanol alters the expression of several chromatin remodeling genes measured by quantitative PCR array analyses. The identified effects were independent of selected lines, which, however, displayed baseline differences in epigenetic gene expression. We reported dysregulation in the expression of genes involved in histone acetylation, deacetylation, lysine and arginine methylation and ubiquitinationhylation during chronic ethanol exposure and withdrawal, but not after 21 days of abstinence. Ethanol-induced changes are consistent with decreased histone acetylation and with decreased deposition of the permissive ubiquitination mark H2BK120ub, associated with reduced transcription. On the other hand, ethanol-induced changes in the expression of genes involved in histone lysine methylation are consistent with increased transcription. The net result of these modifications on gene expression is likely to depend on the combination of the specific histone tail modifications present at a given time on a given promoter. Since alcohol does not modulate gene expression unidirectionally, it is not surprising that alcohol does not unidirectionally alter chromatin structure toward a closed or open state, as suggested by the results of this study. Published by Elsevier

  12. Prefrontal cortex expression of chromatin modifier genes in male WSP and WSR mice changes across ethanol dependence, withdrawal, and abstinence

    PubMed Central

    Hashimoto, Joel G.; Gavin, David P.; Wiren, Kristine M.; Crabbe, John C.; Guizzetti, Marina

    2017-01-01

    Alcohol-use disorder (AUD) is a relapsing disorder associated with excessive ethanol consumption. Recent studies support the involvement of epigenetic mechanisms in the development of AUD. Studies carried out so far have focused on a few specific epigenetic modifications. The goal of this project was to investigate gene expression changes of epigenetic regulators that mediate a broad array of chromatin modifications after chronic alcohol exposure, chronic alcohol exposure followed by 8 h withdrawal, and chronic alcohol exposure followed by 21 days of abstinence in Withdrawal-Resistant (WSR) and Withdrawal Seizure-Prone (WSP) selected mouse lines. We found that chronic vapor exposure to highly intoxicating levels of ethanol alters the expression of several chromatin remodeling genes measured by quantitative PCR array analyses. The identified effects were independent of selected lines, which, however, displayed baseline differences in epigenetic gene expression. We reported dysregulation in the expression of genes involved in histone acetylation, deacetylation, lysine and arginine methylation and ubiquitination, and in DNA methylation during chronic ethanol exposure and withdrawal, but not after 21 days of abstinence. Ethanol-induced changes are consistent with decreased histone acetylation and with decreased deposition of the permissive ubiquitination mark H2BK120ub, associated with reduced transcription. On the other hand, ethanol-induced changes in the expression of genes involved in histone lysine methylation are consistent with increased transcription. The net result of these modifications on gene expression is likely to depend on the combination of the specific histone tail modifications present at a given time on a given promoter. Since alcohol does not modulate gene expression unidirectionally, it is not surprising that alcohol does not unidirectionally alter chromatin structure toward a closed or open state, as suggested by the results of this study. PMID

  13. On the interpretation of a possible ~ 750 GeV particle decaying into γγ

    DOE PAGES

    Ellis, John; Ellis, Sebastian A. R.; Quevillon, Jeremie; ...

    2016-03-25

    We consider interpretations of the recent ~3σ reports by the CMS and ATLAS collaborations of a possible X(~ 750 GeV) state decaying into yy final states. We focus on the possibilities that this is a scalar or pseudoscalar electroweak isoscalar state produced by gluon-gluon fusion mediated by loops of heavy fermions. We consider several models for these fermions, including a single vector-like charge 2/3 T quark, a doublet of vector-like quarks (T;B), and a vector-like generation of quarks, with or without leptons that also contribute to the X → yy decay amplitude. We also consider the possibility that X(750) ismore » a dark matter mediator, with a neutral vector-like dark matter particle. These scenarios are compatible with the present and prospective direct limits on vector-like fermions from LHC Runs 1 and 2, as well as indirect constraints from electroweak precision measurements, and we show that the required Yukawa-like couplings between the X particle and the heavy vector-like fermions are small enough to be perturbative so long as the X particle has dominant decay modes into gg and yy. In conclusion, the decays X → ZZ,Zy and W +W - are interesting prospective signatures that may help distinguish between different vector-like fermion scenarios.« less

  14. Solvent Hold Tank Sample Results For MCU-15-750-751-752-: June Monthly Sample

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fondeur, F.; Taylor-Pashow, K.

    2015-10-07

    Savannah River National Laboratory (SRNL) received one set of Solvent Hold Tank (SHT) samples (MCU-15-750, MCU-15-751, and MCU-15-752), pulled on 06/22/2015 for analysis. The samples were combined and analyzed for composition. Analysis of the composite sample MCU-15-750-751-752 indicated a low concentration (~ 49 % of nominal) of the suppressor (TiDG) and slightly lower than nominal concentrations of the extractant (MaxCalix), and of the modifier (Cs-7SB) in the solvent. This analysis confirms the addition of TiDG, MaxCalix, and modifier to the solvent in February 2015. Based on the current monthly sample, the levels of TiDG, MaxCalix, and modifier are sufficient formore » continuing operation without adding a trim at this time but it is recommended that an addition of TiDG, modifier and Isopar™L should be made in the near future. No impurities above the 1000 ppm level were found in this solvent by the Semi-Volatile Organic Analysis (SVOA). No impurities were observed in the Hydrogen Nuclear Magnetic Resonance (HNMR). In addition, up to 13.9 micrograms of mercury per gram of solvent (or 11.5 µg/mL) was detected in this sample. The laboratory will continue to monitor the quality of the solvent in particular for any new impurities or degradation of the solvent components.« less

  15. rf measurements and tuning of the 750 MHz radio frequency quadrupole

    NASA Astrophysics Data System (ADS)

    Koubek, Benjamin; Grudiev, Alexej; Timmins, Marc

    2017-08-01

    In the framework of the program on medical applications a compact 750 MHz RFQ has been designed and built to be used as an injector for a hadron therapy linac. This RFQ was designed to accelerate protons to an energy of 5 MeV within only 2 m length. It is divided into four segments and equipped with 32 tuners in total. The length of the RFQ corresponds to 5 λ which is considered to be close to the limit for field adjustment using only piston tuners. Moreover the high frequency, which is about double the frequency of existing RFQs, results in a sensitive structure and requires careful tuning. In this paper we present the tuning algorithm, the tuning procedure and rf measurements of the RFQ.

  16. 21 CFR 358.750 - Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 5 2013-04-01 2013-04-01 false Labeling of drug products for the control of... DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Drug Products for the Control of Dandruff, Seborrheic Dermatitis, and Psoriasis § 358.750 Labeling of drug products for the control of dandruff, seborrheic...

  17. 21 CFR 358.750 - Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 5 2014-04-01 2014-04-01 false Labeling of drug products for the control of... DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Drug Products for the Control of Dandruff, Seborrheic Dermatitis, and Psoriasis § 358.750 Labeling of drug products for the control of dandruff, seborrheic...

  18. 21 CFR 358.750 - Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 5 2012-04-01 2012-04-01 false Labeling of drug products for the control of... DRUG PRODUCTS FOR OVER-THE-COUNTER HUMAN USE Drug Products for the Control of Dandruff, Seborrheic Dermatitis, and Psoriasis § 358.750 Labeling of drug products for the control of dandruff, seborrheic...

  19. Nimbus 4 IRIS spectra in the 750-1250 wavelengths/cm atmospheric window region

    NASA Technical Reports Server (NTRS)

    Kunde, V. G.; Conrath, B. J.; Hanel, R. A.; Prabhakara, C.

    1974-01-01

    Present operational schemes for infrared remote sounding measurements of surface temperature use the 899 wavelengths/cm atmospheric window region. Spectra from the Nimbus 4 IRIS in the 750 to 1250 wavelengths/cm region are analyzed. Comparison of the actual surface temperature and the observed brightness temperature at 10 wavelengths/cm resolution shows that the clearest windows were at 936 and 960 wavelengths/cm. Although there is a small amount of CO2 absorption in these regions, this is compensated for by a decrease in water vapor continuum absorption. Atmospheric absorption was 0.5 K less than experienced by the 899 wavelengths/cm window.

  20. 78 FR 77699 - Information Collection Request Sent to the Office of Management and Budget (OMB) for Approval...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-12-24

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-HQ-WSR-2013-N292]; [FVWF941009000007B-XXX-FF09W10000; FVWF51100900000-XXX-FF09W10000] Information Collection Request Sent to the Office of... technology constraints. We expanded to a cloud-computing environment in October 2012, and, effective January...

  1. A 750 GeV portal: LHC phenomenology and dark matter candidates

    DOE PAGES

    D’Eramo, Francesco; de Vries, Jordy; Panci, Paolo

    2016-05-16

    We study the effective field theory obtained by extending the Standard Model field content with two singlets: a 750 GeV (pseudo-)scalar and a stable fermion. Accounting for collider productions initiated by both gluon and photon fusion, we investigate where the theory is consistent with both the LHC diphoton excess and bounds from Run 1. We analyze dark matter phenomenology in such regions, including relic density constraints as well as collider, direct, and indirect bounds. Scalar portal dark matter models are very close to limits from direct detection and mono-jet searches if gluon fusion dominates, and not constrained at all otherwise.more » In conclusion, pseudo-scalar models are challenged by photon line limits and mono-jet searches in most of the parameter space.« less

  2. A 750 GeV portal: LHC phenomenology and dark matter candidates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    D’Eramo, Francesco; de Vries, Jordy; Panci, Paolo

    We study the effective field theory obtained by extending the Standard Model field content with two singlets: a 750 GeV (pseudo-)scalar and a stable fermion. Accounting for collider productions initiated by both gluon and photon fusion, we investigate where the theory is consistent with both the LHC diphoton excess and bounds from Run 1. We analyze dark matter phenomenology in such regions, including relic density constraints as well as collider, direct, and indirect bounds. Scalar portal dark matter models are very close to limits from direct detection and mono-jet searches if gluon fusion dominates, and not constrained at all otherwise.more » In conclusion, pseudo-scalar models are challenged by photon line limits and mono-jet searches in most of the parameter space.« less

  3. Alluvial Bars of the Obed Wild and Scenic River, Tennessee

    USGS Publications Warehouse

    Wolfe, W.J.; Fitch, K.C.; Ladd, D.E.

    2007-01-01

    In 2004, the U.S. Geological Survey (USGS) and the National Park Service (NPS) initiated a reconnaissance study of alluvial bars along the Obed Wild and Scenic River (Obed WSR), in Cumberland and Morgan Counties, Tennessee. The study was partly driven by concern that trapping of sand by upstream impoundments might threaten rare, threatened, or endangered plant habitat by reducing the supply of sediment to the alluvial bars. The objectives of the study were to: (1) develop a preliminary understanding of the distribution, morphology, composition, stability, and vegetation structure of alluvial bars along the Obed WSR, and (2) determine whether evidence of human alteration of sediment dynamics in the Obed WSR warrants further, more detailed examination. This report presents the results of the reconnaissance study of alluvial bars along the Obed River, Clear Creek, and Daddys Creek in the Obed WSR. The report is based on: (1) field-reconnaissance visits by boat to 56 alluvial bars along selected reaches of the Obed River and Clear Creek; (2) analysis of aerial photographs, topographic and geologic maps, and other geographic data to assess the distribution of alluvial bars in the Obed WSR; (3) surveys of topography, surface particle size, vegetation structure, and ground cover on three selected alluvial bars; and (4) analysis of hydrologic records.

  4. Design of a novel bilayered gastric mucoadhesive system for localized and unidirectional release of lamotrigine

    PubMed Central

    Mohana Raghava Srivalli, K.; Lakshmi, P.K.; Balasubramaniam, J.

    2012-01-01

    Lamotrigine is a BCS class II drug with pH dependent solubility. The bilayered gastric mucoadhesive tablets of lamotrigine were designed such that the drug and controlled release polymers were incorporated in the upper layer and the lower layer had the mucoadhesive polymers. The major ingredients selected for the upper layer were the drug and control release polymer (either HPMC K15M or polyox) while the lower MA layer predominantly comprised of Carbopol 974P. A 23 full factorial design was constructed for this study and the tablets were optimized for parameters like tablet size, shape, ex vivo mucoadhesive properties and unidirectional drug release. Oval tablets with an average size of 14 mm diameter were set optimum. Maximum mucoadhesive bond strength of 79.3 ± 0.91 * 103 dyn/cm2 was achieved with carbopol when used in combination with a synergistic resin polymer. All the tested formulations presented a mucoadhesion time of greater than 12 h. The incorporation of methacrylic polymers in the lower layer ensured unidirectional drug release from the bilayered tablets. The unidirectional drug release was confirmed after comparing the dissolution results of paddle method with those of a modified basket method. Model independent similarity and dissimilarity factor methods were used for the comparison of dissolution results. Controlled drug release profiles with zero order kinetics were obtained with polyox and HPMC K15M which reported t90% at 6th and 12th hours, respectively. The “n” value with polyox was 0.992 and that with HPMC K15M was 0.946 indicating an approximate case II transport. These two formulations showed the potential for oral administration of lamotrigine as bilayered gastric mucoadhesive tablets by yielding highest similarity factor values, 96.06 and 92.47, respectively, between the paddle and modified basket method dissolution release profiles apart from reporting the best tablet physical properties and maximum mucoadhesive strength. PMID

  5. Chiral heavy fermions in a two Higgs doublet model: 750 GeV resonance or not

    NASA Astrophysics Data System (ADS)

    Bar-Shalom, Shaouly; Soni, Amarjit

    2017-03-01

    We revisit models where a heavy chiral 4th generation doublet of fermions is embedded in a class of two Higgs doublets models (2HDM) with a discrete Z2 symmetry, which couples the ;heavy; scalar doublet only to the 4th generation fermions and the ;light; one to the Standard Model (SM) fermions - the so-called 4G2HDM introduced by us several years ago. We study the constraints imposed on the 4G2HDM from direct searches of heavy fermions, from precision electroweak data (PEWD) and from the measured production and decay signals of the 125 GeV scalar, which in the 4G2HDM corresponds to the lightest CP-even scalar h. We then show that the recently reported excess in the γγ spectrum around 750 GeV can be accommodated by the heavy CP-even scalar of the 4G2HDM, H, resulting in a unique choice of parameter space: negligible mixing (sin ⁡ α ≲ O (10-3)) between the two CP-even scalars h , H and heavy 4th generation quark and lepton masses mt‧ ,mb‧ ≲ 400 GeV and mν‧ ,mτ‧ ≳ 900 GeV, respectively. Whether or not the 750 GeV γγ resonance is confirmed, interesting phenomenology emerges in q‧ - Higgs systems (q‧ =t‧ ,b‧), that can be searched for at the LHC. For example, the heavy scalar states of the model, S = H , A ,H+, may have BR (S →qbar‧q‧) ∼ O (1), giving rise to observable qbar‧q‧ signals on resonance, followed by the flavor changing q‧ decays t‧ → uh (u = u , c) and/or b‧ → dh (d = d , s , b). This leads to rather distinct signatures, with or without charged leptons, of the form qbar‧q‧ →(nj + mb + ℓW) S (j and b being light and b-quark jets, respectively), with n + m + ℓ = 6- 8 and unique kinematic features. These high jet-multiplicity signals appear to be very challenging and may need new search strategies for detection of such heavy chiral quarks. It is also shown that the flavor structure of the 4G2HDM can easily accommodate the interesting recent indications of a percent-level branching ratio in the

  6. Safety and Pharmacokinetics of Multiple 750-Milligram Doses of Intravenous Levofloxacin in Healthy Volunteers

    PubMed Central

    Chow, Andrew T.; Fowler, Cynthia; Williams, R. Rex; Morgan, Nancy; Kaminski, Susan; Natarajan, Jaya

    2001-01-01

    The safety and pharmacokinetics of a once-daily high intravenous dose of levofloxacin (750 mg) in 18 healthy volunteers were studied in a double-blind, randomized, placebo-controlled, single-center parallel group study. Levofloxacin was well tolerated, and higher maximum concentration of drug in serum and area under the concentration-time curve values were achieved. For difficult-to-treat infections, high daily doses of levofloxacin may be beneficial, and intravenous administration may be preferred in certain clinical settings, such as when treating patients in intensive care units, warranting further evaluation. PMID:11408234

  7. Safety and pharmacokinetics of multiple 750-milligram doses of intravenous levofloxacin in healthy volunteers.

    PubMed

    Chow, A T; Fowler, C; Williams, R R; Morgan, N; Kaminski, S; Natarajan, J

    2001-07-01

    The safety and pharmacokinetics of a once-daily high intravenous dose of levofloxacin (750 mg) in 18 healthy volunteers were studied in a double-blind, randomized, placebo-controlled, single-center parallel group study. Levofloxacin was well tolerated, and higher maximum concentration of drug in serum and area under the concentration-time curve values were achieved. For difficult-to-treat infections, high daily doses of levofloxacin may be beneficial, and intravenous administration may be preferred in certain clinical settings, such as when treating patients in intensive care units, warranting further evaluation.

  8. Coherent Synchrotron Radiation for Rotational Spectroscopy: Application to the Rotational Spectrum of Propynal in the 200-750 GHz Range

    NASA Astrophysics Data System (ADS)

    Barros, J.; Roy, P.; Appadoo, D.; Naughton, D. Mc; Robertson, E.; Manceron, L.

    2013-06-01

    In storage rings, short electron bunches can produce an intense THz radiation called Coherent Synchrotron Radiation (CSR). The flux of this emission between 250 and 750 GHz (in the mW range, up the 10000 times the regular synchrotron emission) is very advantageous for broad band absorption spectroscopy, using interferometric techniques. This source is, however, inherently difficult to stabilize, and intensity fluctuations lead to artifacts on the FT-based measurements, which strongly limit the use of CSR in particular for high-resolution measurements. At SOLEIL however, by screening different currents and bunch lengths, we defined stable CSR conditions for which the signal-to-noise ratio (S/N) allows for measurements at high resolution. Moreover, we developed an artifact correction system, based on a simultaneous detection of the input and the output signals of the interferometer, which allows to further improve the S/N. For this purpose, the optics and electronics of two bolometers were matched. The stable CSR combined with this ingenious technique allowed us to record for the first time high-resolution FT spectra in the sub-THz range, with a S/N of 100 in a few hours. This enables many applications such as broadband rotational spectra in the THz range, studies of molecules with low frequency torsional modes, absolute intensities determinations, or studies of unstable species. Results obtained on Propynal illustrate these possibilities and enabled to improve significantly the ground state spectroscopic constants.

  9. A Simulation-Based Comparison of Several Stochastic Linear Regression Methods in the Presence of Outliers.

    ERIC Educational Resources Information Center

    Rule, David L.

    Several regression methods were examined within the framework of weighted structural regression (WSR), comparing their regression weight stability and score estimation accuracy in the presence of outlier contamination. The methods compared are: (1) ordinary least squares; (2) WSR ridge regression; (3) minimum risk regression; (4) minimum risk 2;…

  10. Baseline Fracture Toughness and CGR testing of alloys X-750 and XM-19 (EPRI Phase I)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. H. Jackson; S. P. Teysseyre

    2012-10-01

    The Advanced Test Reactor National Scientific User Facility (ATR NSUF) and Electric Power Research Institute (EPRI) formed an agreement to test representative alloys used as reactor structural materials as a pilot program toward establishing guidelines for future ATR NSUF research programs. This report contains results from the portion of this program established as Phase I (of three phases) that entails baseline fracture toughness, stress corrosion cracking (SCC), and tensile testing of selected materials for comparison to similar tests conducted at GE Global Research. The intent of this Phase I research program is to determine baseline properties for the materials ofmore » interest prior to irradiation, and to ensure comparability between laboratories using similar testing techniques, prior to applying these techniques to the same materials after having been irradiated at the Advanced Test Reactor (ATR). The materials chosen for this research are the nickel based super alloy X-750, and nitrogen strengthened austenitic stainless steel XM-19. A spare core shroud upper support bracket of alloy X-750 was purchased by EPRI from Southern Co. and a section of XM-19 plate was purchased by EPRI from GE-Hitachi. These materials were sectioned at GE Global Research and provided to INL.« less

  11. Baseline Fracture Toughness and CGR testing of alloys X-750 and XM-19 (EPRI Phase I)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    J. H. Jackson; S. P. Teysseyre

    2012-02-01

    The Advanced Test Reactor National Scientific User Facility (ATR NSUF) and Electric Power Research Institute (EPRI) formed an agreement to test representative alloys used as reactor structural materials as a pilot program toward establishing guidelines for future ATR NSUF research programs. This report contains results from the portion of this program established as Phase I (of three phases) that entails baseline fracture toughness, stress corrosion cracking (SCC), and tensile testing of selected materials for comparison to similar tests conducted at GE Global Research. The intent of this Phase I research program is to determine baseline properties for the materials ofmore » interest prior to irradiation, and to ensure comparability between laboratories using similar testing techniques, prior to applying these techniques to the same materials after having been irradiated at the Advanced Test Reactor (ATR). The materials chosen for this research are the nickel based super alloy X-750, and nitrogen strengthened austenitic stainless steel XM-19. A spare core shroud upper support bracket of alloy X-750 was purchased by EPRI from Southern Co. and a section of XM-19 plate was purchased by EPRI from GE-Hitachi. These materials were sectioned at GE Global Research and provided to INL.« less

  12. New software methods in radar ornithology using WSR-88D weather data and potential application to monitoring effects of climate change on bird migration

    USGS Publications Warehouse

    Mead, Reginald; Paxton, John; Sojda, Richard S.; Swayne, David A.; Yang, Wanhong; Voinov, A.A.; Rizzoli, A.; Filatova, T.

    2010-01-01

    Radar ornithology has provided tools for studying the movement of birds, especially related to migration. Researchers have presented qualitative evidence suggesting that birds, or at least migration events, can be identified using large broad scale radars such as the WSR-88D used in the NEXRAD weather surveillance system. This is potentially a boon for ornithologists because such data cover a large portion of the United States, are constantly being produced, are freely available, and have been archived since the early 1990s. A major obstacle to this research, however, has been that identifying birds in NEXRAD data has required a trained technician to manually inspect a graphically rendered radar sweep. A single site completes one volume scan every five to ten minutes, producing over 52,000 volume scans in one year. This is an immense amount of data, and manual classification is infeasible. We have developed a system that identifies biological echoes using machine learning techniques. This approach begins with training data using scans that have been classified by experts, or uses bird data collected in the field. The data are preprocessed to ensure quality and to emphasize relevant features. A classifier is then trained using this data and cross validation is used to measure performance. We compared neural networks, naive Bayes, and k-nearest neighbor classifiers. Empirical evidence is provided showing that this system can achieve classification accuracies in the 80th to 90th percentile. We propose to apply these methods to studying bird migration phenology and how it is affected by climate variability and change over multiple temporal scales.

  13. Tribological behavior of 440C martensitic stainless steel from -184 C to 750 C

    NASA Technical Reports Server (NTRS)

    Slifka, A. J.; Compos, R.; Morgan, T. J.; Siegwarth, J. D.; Chaudhuri, Dilip K.

    1992-01-01

    Characterization of the coefficient of friction and wear rate of 440C stainless steel is needed to understand the effects of frictional heating in the bearings of the High Pressure Oxygen Turbopump of the Space Shuttle Main Engine. The coefficient of friction and wear rate have been measured over a range of temperature varying from liquid oxygen temperature (-184 C) to 750 C. The normal load has also been varied resulting in a variation of Hertzian stress from 0.915 to 3.660 GPa while the surface velocity has been varied from 0.5 to 2.0 m/s.

  14. 40 CFR Table 1 to Subpart W of... - General Provisions Applicability to Subpart W

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Subpart W 1 Table 1 to Subpart W of Part 63 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY... Polyamides Production Pt. 63, Subpt. W, Table 1 Table 1 to Subpart W of Part 63—General Provisions Applicability to Subpart W Reference Applies to subpart W BLR WSR WSR alternative standard, and BLR equipment...

  15. 25 CFR 162.587 - What happens if BIA disapproves an amendment, assignment, sublease, or leasehold mortgage of a...

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false What happens if BIA disapproves an amendment, assignment, sublease, or leasehold mortgage of a WSR lease? 162.587 Section 162.587 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease...

  16. 25 CFR 162.587 - What happens if BIA disapproves an amendment, assignment, sublease, or leasehold mortgage of a...

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false What happens if BIA disapproves an amendment, assignment, sublease, or leasehold mortgage of a WSR lease? 162.587 Section 162.587 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR LAND AND WATER LEASES AND PERMITS Wind and Solar Resource Leases Wsr Lease...

  17. Pharmacokinetics and pharmacodynamics of intravenous levofloxacin at 750 milligrams and various doses of metronidazole in healthy adult subjects.

    PubMed

    Sprandel, Kelly A; Schriever, Christopher A; Pendland, Susan L; Quinn, John P; Gotfried, Mark H; Hackett, Suzanne; Graham, Mary Beth; Danziger, Larry H; Rodvold, Keith A

    2004-12-01

    The purpose of this investigation was to evaluate the steady-state pharmacokinetics, pharmacodynamics, and safety of intravenous levofloxacin at 750 mg administered once daily combined with three different dosages of intravenous metronidazole (500 mg every 8 h [q8h], 1,000 mg q24h, and 1,500 mg q24h). Eighteen healthy adult subjects received all three combinations in a randomized, crossover fashion. Serial blood and urine samples were collected on the third day of each study period. The 24-h areas under the inhibitory (AUIC(0-24)) and bactericidal (AUBC(0-24)) curves of these three combination regimens were determined against clinical isolates of Bacteroides fragilis, Bacteroides thetaiotaomicron, Peptostreptococcus asaccharolyticus, and Escherichia coli. The mean concentrations of levofloxacin were not different between study periods and were similar to those previously published. The mean (+/- standard deviation) areas under the metronidazole plasma concentration-time curve (AUC(0-24)) for 1,500-mg q24h (338 +/- 105 mg.h/liter) and 500-mg q8h (356 +/- 68 mg.h/liter) regimens were not different (P > 0.05), but both were significantly higher than the 1,000-mg q24h AUC(0-24) (P < 0.05, 227 +/- 57 mg.h/liter). Mean (+/- standard deviation) total body clearance and renal clearance values were similar among the 500-mg q8h, 1,000-mg q24, and 1,500-mg q24h regimens (62 +/- 7, 67 +/- 13, and 67 +/- 14 and 11 +/- 3, 12 +/- 2, and 12 +/- 5 ml/min/1.73 m2, respectively). Levofloxacin at 750 mg q24h plus metronidazole at 500 mg q8h or 1,500 mg q24h resulted in similar AUIC(0-24) and AUBC(0-24) values with one exception: the AUIC(0-24) for the 1,500-mg q24h regimen against B. thetaiotamicron was significantly higher (P < 0.05) than those of the other regimens. Overall, the combination of levofloxacin at 750 mg once daily and metronidazole at 500 mg q8h or 1,500 mg q24h appeared to have greater AUIC(0-24) and AUBC(0-24) values than did the 1,000-mg q24h regimen. All combination

  18. Pharmacokinetics and Pharmacodynamics of Intravenous Levofloxacin at 750 Milligrams and Various Doses of Metronidazole in Healthy Adult Subjects

    PubMed Central

    Sprandel, Kelly A.; Schriever, Christopher A.; Pendland, Susan L.; Quinn, John P.; Gotfried, Mark H.; Hackett, Suzanne; Graham, Mary Beth; Danziger, Larry H.; Rodvold, Keith A.

    2004-01-01

    The purpose of this investigation was to evaluate the steady-state pharmacokinetics, pharmacodynamics, and safety of intravenous levofloxacin at 750 mg administered once daily combined with three different dosages of intravenous metronidazole (500 mg every 8 h [q8h], 1,000 mg q24h, and 1,500 mg q24h). Eighteen healthy adult subjects received all three combinations in a randomized, crossover fashion. Serial blood and urine samples were collected on the third day of each study period. The 24-h areas under the inhibitory (AUIC0-24) and bactericidal (AUBC0-24) curves of these three combination regimens were determined against clinical isolates of Bacteroides fragilis, Bacteroides thetaiotaomicron, Peptostreptococcus asaccharolyticus, and Escherichia coli. The mean concentrations of levofloxacin were not different between study periods and were similar to those previously published. The mean (± standard deviation) areas under the metronidazole plasma concentration-time curve (AUC0-24) for 1,500-mg q24h (338 ± 105 mg · h/liter) and 500-mg q8h (356 ± 68 mg · h/liter) regimens were not different (P > 0.05), but both were significantly higher than the 1,000-mg q24h AUC0-24 (P < 0.05, 227 ± 57 mg · h/liter). Mean (± standard deviation) total body clearance and renal clearance values were similar among the 500-mg q8h, 1,000-mg q24, and 1,500-mg q24h regimens (62 ± 7, 67 ± 13, and 67 ± 14 and 11 ± 3, 12 ± 2, and 12 ± 5 ml/min/1.73 m2, respectively). Levofloxacin at 750 mg q24h plus metronidazole at 500 mg q8h or 1,500 mg q24h resulted in similar AUIC0-24 and AUBC0-24 values with one exception: the AUIC0-24 for the 1,500-mg q24h regimen against B. thetaiotamicron was significantly higher (P < 0.05) than those of the other regimens. Overall, the combination of levofloxacin at 750 mg once daily and metronidazole at 500 mg q8h or 1,500 mg q24h appeared to have greater AUIC0-24 and AUBC0-24 values than did the 1,000-mg q24h regimen. All combination

  19. Relationship between skin diseases and extracutaneous complications of diabetes mellitus: clinical analysis of 750 patients.

    PubMed

    Demirseren, Duriye Deniz; Emre, Selma; Akoglu, Gulsen; Arpacı, Dilek; Arman, Aysegul; Metin, Ahmet; Cakır, Bekir

    2014-02-01

    The relationship between skin diseases and extracutaneous complications in diabetes mellitus (DM) is unclear. We aimed to investigate the relationship between skin disorders and diabetic neuropathy, nephropathy, and retinopathy in patients with DM. A total of 750 patients with DM were prospectively enrolled. Demographic and clinical features, skin disorders, glycosylated hemoglobin (HbA1c) levels, and presence of nephropathy, neuropathy, and retinopathy were noted. Of the patients, 38.0% had neuropathy, 23.3% had nephropathy, and 22.9% had retinopathy. Any skin disorder was present in 79.2% (n = 594) of patients. The most common skin manifestations were cutaneous infections (47.5%), xerosis (26.4%), and inflammatory skin diseases (20.7%). The frequency of cutaneous infections, fungal infections, diabetic foot, rubeosis faciei, and pigmented purpuric dermatitis was higher in patients with nephropathy than in those without nephropathy. Cutaneous infections, diabetic foot, rubeosis faciei, and diabetic dermopathy were more common in patients with neuropathy. Fungal infections, diabetic foot, rubeosis faciei, diabetic dermopathy, and pigmented purpuric dermatitis were more frequent in patients with retinopathy. Patients with HbA1c ≥8 mmol/mL had more skin disorders than those with HbA1c <8 mmol/mL (P < 0.05 for all). Skin disorders may be clues to the presence of associated microvascular complications of DM.

  20. Microstructural analysis of Ti/Al/Ti/Au ohmic contacts to n-AlGaN/GaN

    NASA Astrophysics Data System (ADS)

    Chen, J.; Ivey, D. G.; Bardwell, J.; Liu, Y.; Tang, H.; Webb, J. B.

    2002-05-01

    To develop high quality AlGaN/GaN heterostructure field effect transistors for use in high power, high frequency, and high temperature applications, low resistance, thermal stable ohmic contacts with good surface morphology are essential. Low specific contact resistances have been achieved using an Au/Ti/Al/Ti contact: a minimum value of 6.33×10-6 Ω cm2 was attained after annealing at 700 °C for 30 s. Microstructural analysis using transmission electron microscopy indicated that there is significant interaction between the metallization components and the semiconductor during annealing. The optimum electrical properties correspond to a microstructure that consists of Au2Ti and TiAl layers as well as of a thin Ti-rich layer (~10 nm thick) at the metallization/AlGaN interface. Degradation of the contact occurred for annealing temperatures in excess of 750 °C, and was accompanied by decomposition of the AlGaN layer and formation of a Au-Ti-Al-Ga quaternary phase.

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