Sample records for na alemanha 1918-1933

  1. Single gene reassortants identify a critical role for PB1, HA, and NA in the high virulence of the 1918 pandemic influenza virus

    PubMed Central

    Pappas, Claudia; Aguilar, Patricia V.; Basler, Christopher F.; Solórzano, Alicia; Zeng, Hui; Perrone, Lucy A.; Palese, Peter; García-Sastre, Adolfo; Katz, Jacqueline M.; Tumpey, Terrence M.

    2008-01-01

    The 1918 influenza pandemic was exceptionally severe, resulting in the death of up to 50 million people worldwide. Here, we show which virus genes contributed to the replication and virulence of the 1918 influenza virus. Recombinant viruses, in which genes of the 1918 virus were replaced with genes from a contemporary human H1N1 influenza virus, A/Texas/36/91 (Tx/91), were generated. The exchange of most 1918 influenza virus genes with seasonal influenza H1N1 virus genes did not alter the virulence of the 1918 virus; however, substitution of the hemagglutinin (HA), neuraminidase (NA), or polymerase subunit PB1 genes significantly affected the ability of this virus to cause severe disease in mice. The 1918 virus virulence observed in mice correlated with the ability of 1918 recombinant viruses to replicate efficiently in human airway cells. In a second series of experiments, eight 1918 1:7 recombinants were generated, in which each Tx/91 virus gene was individually replaced by a corresponding gene from 1918 virus. Replication capacity of the individual 1:7 reassortant viruses was assessed in mouse lungs and human airway cells. Increased virus titers were observed among 1:7 viruses containing individual 1918 HA, NA, and PB1 genes. In addition, the 1918 PB1:Tx/91 (1:7) virus showed a distinctly larger plaque size phenotype than the small plaque phenotype of the 1918 PA:Tx/91 and 1918 PB2:Tx/91 1:7 reassortants. These results highlight the importance of the 1918 HA, NA, and PB1 genes for optimal virus replication and virulence of this pandemic strain. PMID:18287069

  2. Existing antivirals are effective against influenza viruses with genes from the 1918 pandemic virus.

    PubMed

    Tumpey, Terrence M; García-Sastre, Adolfo; Mikulasova, Andrea; Taubenberger, Jeffery K; Swayne, David E; Palese, Peter; Basler, Christopher F

    2002-10-15

    The 1918 influenza pandemic caused more than 20 million deaths worldwide. Thus, the potential impact of a re-emergent 1918 or 1918-like influenza virus, whether through natural means or as a result of bioterrorism, is of significant concern. The genetic determinants of the virulence of the 1918 virus have not been defined yet, nor have specific clinical prophylaxis and/or treatment interventions that would be effective against a re-emergent 1918 or 1918-like virus been identified. Based on the reported nucleotide sequences, we have reconstructed the hemagglutinin (HA), neuraminidase (NA), and matrix (M) genes of the 1918 virus. Under biosafety level 3 (agricultural) conditions, we have generated recombinant influenza viruses bearing the 1918 HA, NA, or M segments. Strikingly, recombinant viruses possessing both the 1918 HA and 1918 NA were virulent in mice. In contrast, a control virus with the HA and NA from a more recent human isolate was unable to kill mice at any dose tested. The recombinant viruses were also tested for their sensitivity to U.S. Food and Drug Administration-approved antiinfluenza virus drugs in vitro and in vivo. Recombinant viruses possessing the 1918 NA or both the 1918 HA and 1918 NA were inhibited effectively in both tissue culture and mice by the NA inhibitors, zanamivir and oseltamivir. A recombinant virus possessing the 1918 M segment was inhibited effectively both in tissue culture and in vivo by the M2 ion-channel inhibitors amantadine and rimantadine. These data suggest that current antiviral strategies would be effective in curbing the dangers of a re-emergent 1918 or 1918-like virus.

  3. 29 CFR 1918.55 - Cranes (See also § 1918.11).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Cranes (See also § 1918.11). 1918.55 Section 1918.55 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Vessel's Cargo Handling Gear § 1918.55 Cranes (See also § 1918.11). The following requirements shall apply to the use of cranes forming part of a vessel's...

  4. 29 CFR 1918.25 - Bridge plates and ramps (See also § 1918.86).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Bridge plates and ramps (See also § 1918.86). 1918.25... Means of Access § 1918.25 Bridge plates and ramps (See also § 1918.86). (a) Bridge and car plates (dockboards). Bridge and car plates used afloat shall be well maintained and shall: (1) Be strong enough to...

  5. 29 CFR 1918.25 - Bridge plates and ramps (See also § 1918.86).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Bridge plates and ramps (See also § 1918.86). 1918.25... Means of Access § 1918.25 Bridge plates and ramps (See also § 1918.86). (a) Bridge and car plates (dockboards). Bridge and car plates used afloat shall be well maintained and shall: (1) Be strong enough to...

  6. 22 CFR 193.3 - Applications.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Applications. 193.3 Section 193.3 Foreign Relations DEPARTMENT OF STATE HOSTAGE RELIEF BENEFITS FOR HOSTAGES IN IRAQ, KUWAIT, OR LEBANON § 193.3.../Iraq/Lebanon Hostage Benefits Program, room 4817, Department of State, Washington, DC 20520-4818. (e...

  7. 32 CFR 193.3 - Policy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Policy. 193.3 Section 193.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS HIGHWAYS FOR NATIONAL DEFENSE § 193.3 Policy. In order to insure that the national defense is served by adequate, safe...

  8. 32 CFR 193.3 - Policy.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 2 2014-07-01 2014-07-01 false Policy. 193.3 Section 193.3 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS HIGHWAYS FOR NATIONAL DEFENSE § 193.3 Policy. In order to insure that the national defense is served by adequate, safe...

  9. 29 CFR 1918.93 - Hazardous atmospheres and substances (See also § 1918.2).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Hazardous atmospheres and substances (See also § 1918.2... Conditions. § 1918.93 Hazardous atmospheres and substances (See also § 1918.2). (a) Purpose and scope. This section covers areas in which the employer knows, or has reason to believe, that a hazardous atmosphere or...

  10. 29 CFR 1918.93 - Hazardous atmospheres and substances (See also § 1918.2).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Hazardous atmospheres and substances (See also § 1918.2... Conditions. § 1918.93 Hazardous atmospheres and substances (See also § 1918.2). (a) Purpose and scope. This section covers areas in which the employer knows, or has reason to believe, that a hazardous atmosphere or...

  11. 29 CFR 1918.93 - Hazardous atmospheres and substances (See also § 1918.2).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Hazardous atmospheres and substances (See also § 1918.2... Conditions. § 1918.93 Hazardous atmospheres and substances (See also § 1918.2). (a) Purpose and scope. This section covers areas in which the employer knows, or has reason to believe, that a hazardous atmosphere or...

  12. 29 CFR 1918.93 - Hazardous atmospheres and substances (See also § 1918.2).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Hazardous atmospheres and substances (See also § 1918.2... Conditions. § 1918.93 Hazardous atmospheres and substances (See also § 1918.2). (a) Purpose and scope. This section covers areas in which the employer knows, or has reason to believe, that a hazardous atmosphere or...

  13. 29 CFR 1918.90 - Hazard communication.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Hazard communication. 1918.90 Section 1918.90 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING General Working Conditions. § 1918.90 Hazard...

  14. 29 CFR 1918.102 - Respiratory protection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Respiratory protection. 1918.102 Section 1918.102 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Respiratory protection. (See § 1918.1(b)(8)). [65 FR 40946, June 30, 2000] ...

  15. 29 CFR 1918.102 - Respiratory protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Respiratory protection. 1918.102 Section 1918.102 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Respiratory protection. (See § 1918.1(b)(8)). [65 FR 40946, June 30, 2000] ...

  16. 29 CFR 1918.102 - Respiratory protection.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Respiratory protection. 1918.102 Section 1918.102 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Respiratory protection. (See § 1918.1(b)(8)). [65 FR 40946, June 30, 2000] ...

  17. 29 CFR 1918.102 - Respiratory protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Respiratory protection. 1918.102 Section 1918.102 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Respiratory protection. (See § 1918.1(b)(8)). [65 FR 40946, June 30, 2000] ...

  18. 29 CFR 1918.102 - Respiratory protection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Respiratory protection. 1918.102 Section 1918.102 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR... Respiratory protection. (See § 1918.1(b)(8)). [65 FR 40946, June 30, 2000] ...

  19. 29 CFR 1918.82 - Building drafts.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Building drafts. 1918.82 Section 1918.82 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.82 Building drafts. (a) Drafts shall...

  20. 29 CFR 1918.82 - Building drafts.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Building drafts. 1918.82 Section 1918.82 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.82 Building drafts. (a) Drafts shall...

  1. 29 CFR 1918.82 - Building drafts.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Building drafts. 1918.82 Section 1918.82 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.82 Building drafts. (a) Drafts shall...

  2. 29 CFR 1918.82 - Building drafts.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Building drafts. 1918.82 Section 1918.82 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.82 Building drafts. (a) Drafts shall...

  3. 29 CFR 1918.35 - Open hatches.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Open hatches. 1918.35 Section 1918.35 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.35 Open hatches. Open weather deck...

  4. 29 CFR 1918.35 - Open hatches.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Open hatches. 1918.35 Section 1918.35 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.35 Open hatches. Open weather deck...

  5. 29 CFR 1918.35 - Open hatches.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Open hatches. 1918.35 Section 1918.35 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.35 Open hatches. Open weather deck...

  6. 29 CFR 1918.35 - Open hatches.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Open hatches. 1918.35 Section 1918.35 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.35 Open hatches. Open weather deck...

  7. 29 CFR 1918.35 - Open hatches.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Open hatches. 1918.35 Section 1918.35 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.35 Open hatches. Open weather deck...

  8. 29 CFR 1918.31 - Hatch coverings.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Hatch coverings. 1918.31 Section 1918.31 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.31 Hatch coverings. (a) No cargo... partially opened intermediate deck unless either the hatch at that deck is sufficiently covered or an...

  9. 29 CFR 1918.31 - Hatch coverings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Hatch coverings. 1918.31 Section 1918.31 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.31 Hatch coverings. (a) No cargo... partially opened intermediate deck unless either the hatch at that deck is sufficiently covered or an...

  10. 29 CFR 1918.31 - Hatch coverings.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Hatch coverings. 1918.31 Section 1918.31 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.31 Hatch coverings. (a) No cargo... partially opened intermediate deck unless either the hatch at that deck is sufficiently covered or an...

  11. 29 CFR 1918.31 - Hatch coverings.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Hatch coverings. 1918.31 Section 1918.31 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.31 Hatch coverings. (a) No cargo... partially opened intermediate deck unless either the hatch at that deck is sufficiently covered or an...

  12. 29 CFR 1918.31 - Hatch coverings.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Hatch coverings. 1918.31 Section 1918.31 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.31 Hatch coverings. (a) No cargo... partially opened intermediate deck unless either the hatch at that deck is sufficiently covered or an...

  13. 29 CFR 1918.82 - Building drafts.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Building drafts. 1918.82 Section 1918.82 Labor Regulations...) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.82 Building drafts. (a) Drafts shall be built or means shall be taken to prevent cargo from falling from them. (b) Buckets and tubs used...

  14. 29 CFR 1918.105 - Other protective measures.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.105 Other...) When necessary, protective clothing shall be cleaned and disinfected before reissuance. (b) Personal... 29 Labor 7 2011-07-01 2011-07-01 false Other protective measures. 1918.105 Section 1918.105 Labor...

  15. 29 CFR 1918.105 - Other protective measures.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.105 Other...) When necessary, protective clothing shall be cleaned and disinfected before reissuance. (b) Personal... 29 Labor 7 2010-07-01 2010-07-01 false Other protective measures. 1918.105 Section 1918.105 Labor...

  16. 29 CFR 1918.87 - Ship's cargo elevators.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Ship's cargo elevators. 1918.87 Section 1918.87 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.87 Ship's cargo elevators. (a) Safe working load. The safe working loads of ship's cargo elevators shall be determined and followed...

  17. 29 CFR 1918.87 - Ship's cargo elevators.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Ship's cargo elevators. 1918.87 Section 1918.87 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.87 Ship's cargo elevators. (a) Safe working load. The safe working loads of ship's cargo elevators shall be determined and followed...

  18. 29 CFR 1918.87 - Ship's cargo elevators.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Ship's cargo elevators. 1918.87 Section 1918.87 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.87 Ship's cargo elevators. (a) Safe working load. The safe working loads of ship's cargo elevators shall be determined and followed...

  19. 29 CFR 1918.87 - Ship's cargo elevators.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Ship's cargo elevators. 1918.87 Section 1918.87 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.87 Ship's cargo elevators. (a) Safe working load. The safe working loads of ship's cargo elevators shall be determined and followed...

  20. 29 CFR 1918.36 - Weather deck rails.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Weather deck rails. 1918.36 Section 1918.36 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.36 Weather deck rails. Removable weather deck rails shall be kept in place except when cargo operations require them to be removed...

  1. 29 CFR 1918.36 - Weather deck rails.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Weather deck rails. 1918.36 Section 1918.36 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.36 Weather deck rails. Removable weather deck rails shall be kept in place except when cargo operations require them to be removed...

  2. 29 CFR 1918.36 - Weather deck rails.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Weather deck rails. 1918.36 Section 1918.36 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.36 Weather deck rails. Removable weather deck rails shall be kept in place except when cargo operations require them to be removed...

  3. 29 CFR 1918.36 - Weather deck rails.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Weather deck rails. 1918.36 Section 1918.36 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.36 Weather deck rails. Removable weather deck rails shall be kept in place except when cargo operations require them to be removed...

  4. 29 CFR 1918.36 - Weather deck rails.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Weather deck rails. 1918.36 Section 1918.36 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Working Surfaces § 1918.36 Weather deck rails. Removable weather deck rails shall be kept in place except when cargo operations require them to be removed...

  5. 29 CFR 1918.87 - Ship's cargo elevators.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Ship's cargo elevators. 1918.87 Section 1918.87 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.87 Ship's cargo elevators. (a) Safe working load. The safe workin...

  6. 29 CFR 1918.101 - Eye and face protection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Eye and face protection. 1918.101 Section 1918.101 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.101 Eye and... uses appropriate eye and/or face protection when the employee is exposed to an eye or face hazard, and...

  7. 29 CFR 1918.101 - Eye and face protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Eye and face protection. 1918.101 Section 1918.101 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.101 Eye and... uses appropriate eye and/or face protection when the employee is exposed to an eye or face hazard, and...

  8. The 1918–1920 influenza pandemic in Peru

    PubMed Central

    Chowell, G.; Viboud, C.; Simonsen, L.; Miller, M.A.; Hurtado, J.; Soto, G.; Vargas, R.; Guzman, M.A.; Ulloa, M.; Munayco, C.V.

    2011-01-01

    Background Increasing our knowledge of past influenza pandemic patterns in different regions of the world is crucial to guide preparedness plans against future influenza pandemics. Here, we undertook extensive archival collection efforts from 3 representative cities of Peru (Lima in the central coast, Iquitos in the northeastern Amazon region, Ica in the southern coast) to characterize the age and geographic patterns of the 1918–1920 influenza pandemic in this country. Materials and Methods We analyzed historical documents describing the 1918–1920 influenza pandemic in Peru and retrieved individual mortality records from local provincial archives for quantitative analysis. We applied seasonal excess mortality models to daily and monthly respiratory mortality rates for 1917–1920 and quantified transmissibility estimates based on the daily growth rate in respiratory deaths. Results A total of 52,739 individual mortality records were inspected from local provincial archives. We found evidence for an initial mild pandemic wave during July-September 1918 in Lima, identified a synchronized severe pandemic wave of respiratory mortality in all three locations in Peru during November 1918-February 1919, and a severe pandemic wave during January 1920- March 1920 in Lima and July-October 1920 in Ica. There was no recrudescent pandemic wave in 1920 in Iquitos. Remarkably, Lima experienced the brunt of the 1918–20 excess mortality impact during the 1920 recrudescent wave, with all age groups experiencing an increase in all cause excess mortality from 1918–19 to 1920. Middle age groups experienced the highest excess mortality impact, relative to baseline levels, in the 1918–19 and 1920 pandemic waves. Cumulative excess mortality rates for the 1918–20 pandemic period were higher in Iquitos (2.9%) than Lima (1.6%). The mean reproduction number for Lima was estimated in the range 1.3–1.5. Conclusions We identified synchronized pandemic waves of intense excess

  9. 29 CFR 1918.94 - Ventilation and atmospheric conditions (See also § 1918.2, definitions of Hazardous cargo...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., definitions of Hazardous cargo, materials, substance or atmosphere and Ro-Ro operations). 1918.94 Section 1918..., materials, substance or atmosphere and Ro-Ro operations). (a) Ventilation with respect to carbon monoxide... employees are working by persons competent in the use of the test equipment and procedures. If operations...

  10. 29 CFR 1918.94 - Ventilation and atmospheric conditions (See also § 1918.2, definitions of Hazardous cargo...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., definitions of Hazardous cargo, materials, substance or atmosphere and Ro-Ro operations). 1918.94 Section 1918..., materials, substance or atmosphere and Ro-Ro operations). (a) Ventilation with respect to carbon monoxide... employees are working by persons competent in the use of the test equipment and procedures. If operations...

  11. 29 CFR 1918.94 - Ventilation and atmospheric conditions (See also § 1918.2, definitions of Hazardous cargo...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., definitions of Hazardous cargo, materials, substance or atmosphere and Ro-Ro operations). 1918.94 Section 1918..., materials, substance or atmosphere and Ro-Ro operations). (a) Ventilation with respect to carbon monoxide... employees are working by persons competent in the use of the test equipment and procedures. If operations...

  12. 29 CFR 1918.55 - Cranes (See also § 1918.11).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) Operator's station. (1) Cranes with missing, broken, cracked, scratched, or dirty glass (or equivalent...) Unattended cranes. When cranes are left unattended between work periods, § 1918.66(b) (4)(i) through (v...

  13. 29 CFR 1918.55 - Cranes (See also § 1918.11).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) Operator's station. (1) Cranes with missing, broken, cracked, scratched, or dirty glass (or equivalent...) Unattended cranes. When cranes are left unattended between work periods, § 1918.66(b) (4)(i) through (v...

  14. 29 CFR 1918.55 - Cranes (See also § 1918.11).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) Operator's station. (1) Cranes with missing, broken, cracked, scratched, or dirty glass (or equivalent...) Unattended cranes. When cranes are left unattended between work periods, § 1918.66(b) (4)(i) through (v...

  15. 12 CFR 193.3 - Qualification of public accountant.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 1 2013-01-01 2013-01-01 false Qualification of public accountant. 193.3... REQUIREMENTS Form and Content of Financial Statements § 193.3 Qualification of public accountant. The term “qualified public accountant” means a certified public accountant or licensed public accountant certified or...

  16. 12 CFR 193.3 - Qualification of public accountant.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 1 2014-01-01 2014-01-01 false Qualification of public accountant. 193.3... REQUIREMENTS Form and Content of Financial Statements § 193.3 Qualification of public accountant. The term “qualified public accountant” means a certified public accountant or licensed public accountant certified or...

  17. 12 CFR 193.3 - Qualification of public accountant.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 12 Banks and Banking 1 2012-01-01 2012-01-01 false Qualification of public accountant. 193.3... REQUIREMENTS Form and Content of Financial Statements § 193.3 Qualification of public accountant. The term “qualified public accountant” means a certified public accountant or licensed public accountant certified or...

  18. 29 CFR 1918.63 - Chutes, gravity conveyors and rollers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Chutes, gravity conveyors and rollers. 1918.63 Section 1918... Equipment Other Than Ship's Gear § 1918.63 Chutes, gravity conveyors and rollers. (a) Chutes shall be of... and gravity conveyor roller sections shall be firmly placed and secured to prevent displacement...

  19. 29 CFR 1918.63 - Chutes, gravity conveyors and rollers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Chutes, gravity conveyors and rollers. 1918.63 Section 1918... Equipment Other Than Ship's Gear § 1918.63 Chutes, gravity conveyors and rollers. (a) Chutes shall be of... and gravity conveyor roller sections shall be firmly placed and secured to prevent displacement...

  20. 29 CFR 1918.63 - Chutes, gravity conveyors and rollers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Chutes, gravity conveyors and rollers. 1918.63 Section 1918... Equipment Other Than Ship's Gear § 1918.63 Chutes, gravity conveyors and rollers. (a) Chutes shall be of... and gravity conveyor roller sections shall be firmly placed and secured to prevent displacement...

  1. 29 CFR 1918.63 - Chutes, gravity conveyors and rollers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Chutes, gravity conveyors and rollers. 1918.63 Section 1918... Equipment Other Than Ship's Gear § 1918.63 Chutes, gravity conveyors and rollers. (a) Chutes shall be of... and gravity conveyor roller sections shall be firmly placed and secured to prevent displacement...

  2. 29 CFR 1918.63 - Chutes, gravity conveyors and rollers.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Chutes, gravity conveyors and rollers. 1918.63 Section 1918... Equipment Other Than Ship's Gear § 1918.63 Chutes, gravity conveyors and rollers. (a) Chutes shall be of... and gravity conveyor roller sections shall be firmly placed and secured to prevent displacement...

  3. 27 CFR 19.18 - Samples for the United States.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Provisions § 19.18 Samples for the United States. TTB officers are authorized to take samples of spirits... 27 Alcohol, Tobacco Products and Firearms 1 2011-04-01 2011-04-01 false Samples for the United States. 19.18 Section 19.18 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE...

  4. 29 CFR 1918.43 - Handling hatch beams and covers.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Handling hatch beams and covers. 1918.43 Section 1918.43..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.43 Handling hatch beams and covers. Paragraphs (f)(2), (g), and (h) of this section apply only to...

  5. 29 CFR 1918.43 - Handling hatch beams and covers.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Handling hatch beams and covers. 1918.43 Section 1918.43..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.43 Handling hatch beams and covers. Paragraphs (f)(2), (g), and (h) of this section apply only to...

  6. 29 CFR 1918.42 - Hatch beam and pontoon bridles.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Hatch beam and pontoon bridles. 1918.42 Section 1918.42..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.42 Hatch beam and pontoon bridles. (a) Hatch beam and pontoon bridles shall be: (1) Long enough to...

  7. 29 CFR 1918.42 - Hatch beam and pontoon bridles.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Hatch beam and pontoon bridles. 1918.42 Section 1918.42..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.42 Hatch beam and pontoon bridles. (a) Hatch beam and pontoon bridles shall be: (1) Long enough to...

  8. 29 CFR 1918.42 - Hatch beam and pontoon bridles.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Hatch beam and pontoon bridles. 1918.42 Section 1918.42..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.42 Hatch beam and pontoon bridles. (a) Hatch beam and pontoon bridles shall be: (1) Long enough to...

  9. 29 CFR 1918.42 - Hatch beam and pontoon bridles.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Hatch beam and pontoon bridles. 1918.42 Section 1918.42..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.42 Hatch beam and pontoon bridles. (a) Hatch beam and pontoon bridles shall be: (1) Long enough to...

  10. 29 CFR 1918.43 - Handling hatch beams and covers.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Handling hatch beams and covers. 1918.43 Section 1918.43..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.43 Handling hatch beams and covers. Paragraphs (f)(2), (g), and (h) of this section apply only to...

  11. 29 CFR 1918.43 - Handling hatch beams and covers.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Handling hatch beams and covers. 1918.43 Section 1918.43..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.43 Handling hatch beams and covers. Paragraphs (f)(2), (g), and (h) of this section apply only to...

  12. 29 CFR 1918.42 - Hatch beam and pontoon bridles.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Hatch beam and pontoon bridles. 1918.42 Section 1918.42..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.42 Hatch beam and pontoon bridles. (a) Hatch beam and pontoon bridles shall be: (1) Long enough to...

  13. 29 CFR 1918.100 - Emergency action plans.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... emergency action or for reaction time for safe escape of employees from the workplace or the immediate work... 29 Labor 7 2010-07-01 2010-07-01 false Emergency action plans. 1918.100 Section 1918.100 Labor... action plans. (a) Scope and application. This section requires all employers to develop and implement an...

  14. Production of lumber, lath, and shingles in 1918

    Treesearch

    Henry S. Graves

    1920-01-01

    In this bulletin, which is one of an annual series covering the period 1904 to 1918, inclusive, with the exception of 1914, are detailed statistics of the 1918 production of lumber, lath, and shingles in the continental United States, with comparative figures from previous annual reports.

  15. 29 CFR 1918.106 - Payment for protective equipment.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) Ordinary clothing, skin creams, or other items, used solely for protection from weather, such as winter... 29 Labor 7 2011-07-01 2011-07-01 false Payment for protective equipment. 1918.106 Section 1918.106..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment...

  16. 29 CFR 1918.106 - Payment for protective equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) Ordinary clothing, skin creams, or other items, used solely for protection from weather, such as winter... 29 Labor 7 2010-07-01 2010-07-01 false Payment for protective equipment. 1918.106 Section 1918.106..., DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment...

  17. 29 CFR 1918.101 - Eye and face protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Eye and face protection. 1918.101 Section 1918.101 Labor... face protection. (a) The employer shall ensure that: (1)(i) Employers must ensure that each employee uses appropriate eye and/or face protection when the employee is exposed to an eye or face hazard, and...

  18. 29 CFR 1918.101 - Eye and face protection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Eye and face protection. 1918.101 Section 1918.101 Labor... face protection. (a) The employer shall ensure that: (1)(i) Employers must ensure that each employee uses appropriate eye and/or face protection when the employee is exposed to an eye or face hazard, and...

  19. 29 CFR 1918.101 - Eye and face protection.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Eye and face protection. 1918.101 Section 1918.101 Labor... face protection. (a) The employer shall ensure that: (1)(i) Employers must ensure that each employee uses appropriate eye and/or face protection when the employee is exposed to an eye or face hazard, and...

  20. 29 CFR 1918.93 - Hazardous atmospheres and substances (See also § 1918.2).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...; § 1918.94(e), Catch of menhaden and similar species of fish. (b) Determination of the hazard. When the...-contained breathing apparatus which shall be used for entry. (4) To prevent inadvertent employee entry into...

  1. Documents Related to the Flu Pandemic of 1918

    ERIC Educational Resources Information Center

    Mazzone, Raphael; Potter, Lee Ann

    2006-01-01

    This article discusses a worldwide epidemic--a pandemic--that appeared in the United Sates during the latter part of the summer of 1918. During 1918 and 1919, between 50 and 100 million people around the globe fell victim to a rapidly spreading and untreatable strain of influenza. The pandemic so severely affected the U.S. population that roughly…

  2. Reconstruction of the 1918 Influenza Virus: Unexpected Rewards from the Past

    PubMed Central

    Taubenberger, Jeffery K.; Baltimore, David; Doherty, Peter C.; Markel, Howard; Morens, David M.; Webster, Robert G.; Wilson, Ian A.

    2012-01-01

    ABSTRACT The influenza pandemic of 1918–1919 killed approximately 50 million people. The unusually severe morbidity and mortality associated with the pandemic spurred physicians and scientists to isolate the etiologic agent, but the virus was not isolated in 1918. In 1996, it became possible to recover and sequence highly degraded fragments of influenza viral RNA retained in preserved tissues from several 1918 victims. These viral RNA sequences eventually permitted reconstruction of the complete 1918 virus, which has yielded, almost a century after the deaths of its victims, novel insights into influenza virus biology and pathogenesis and has provided important information about how to prevent and control future pandemics. PMID:22967978

  3. 29 CFR Appendix IV to Part 1918 - Special Cargo Gear and Container Spreader Test Requirements (Mandatory) [see § 1918.61 (f), (g...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Special Cargo Gear and Container Spreader Test Requirements... REGULATIONS FOR LONGSHORING Pt. 1918, App. IV Appendix IV to Part 1918—Special Cargo Gear and Container... structural damage repair 3. Intermodal container spreaders not part of vessel's cargo handling gear Prior to...

  4. 29 CFR Appendix IV to Part 1918 - Special Cargo Gear and Container Spreader Test Requirements (Mandatory) [see § 1918.61 (f), (g...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Special Cargo Gear and Container Spreader Test Requirements... REGULATIONS FOR LONGSHORING Pt. 1918, App. IV Appendix IV to Part 1918—Special Cargo Gear and Container... structural damage repair 3. Intermodal container spreaders not part of vessel's cargo handling gear Prior to...

  5. 29 CFR Appendix IV to Part 1918 - Special Cargo Gear and Container Spreader Test Requirements (Mandatory) [see § 1918.61 (f), (g...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Special Cargo Gear and Container Spreader Test Requirements... REGULATIONS FOR LONGSHORING Pt. 1918, App. IV Appendix IV to Part 1918—Special Cargo Gear and Container... structural damage repair 3. Intermodal container spreaders not part of vessel's cargo handling gear Prior to...

  6. 47 CFR 1.1918 - Use of consumer reporting agencies.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Use of consumer reporting agencies. 1.1918... Collection of Claims Owed the United States Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1.1918 Use of consumer reporting agencies. (a) The term individual means a natural person, and...

  7. 47 CFR 1.1918 - Use of consumer reporting agencies.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 47 Telecommunication 1 2011-10-01 2011-10-01 false Use of consumer reporting agencies. 1.1918... Collection of Claims Owed the United States Administrative Offset-Consumer Reporting Agencies-Contracting for Collection § 1.1918 Use of consumer reporting agencies. (a) The term individual means a natural person, and...

  8. Core-6 fucose and the oligomerization of the 1918 pandemic influenza viral neuraminidase

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu, Zhengliang L., E-mail: Leon.wu@bio-techne.com; Zhou, Hui; Ethen, Cheryl M.

    The 1918 H1N1 influenza virus was responsible for one of the most deadly pandemics in human history. Yet to date, the structure component responsible for its virulence is still a mystery. In order to search for such a component, the neuraminidase (NA) antigen of the virus was expressed, which led to the discovery of an active form (tetramer) and an inactive form (dimer and monomer) of the protein due to different glycosylation. In this report, the N-glycans from both forms were released and characterized by mass spectrometry. It was found that the glycans from the active form had 26% core-6more » fucosylated, while the glycans from the inactive form had 82% core-6 fucosylated. Even more surprisingly, the stalk region of the active form was almost completely devoid of core-6-linked fucose. These findings were further supported by the results obtained from in vitro incorporation of azido fucose and {sup 3}H-labeled fucose using core-6 fucosyltransferase, FUT8. In addition, the incorporation of fucose did not change the enzymatic activity of the active form, implying that core-6 fucose is not directly involved in the enzymatic activity. It is postulated that core-6 fucose prohibits the oligomerization and subsequent activation of the enzyme. - Graphical abstract: Proposed mechanism for how core-fucose prohibits the tetramerization of the 1918 pandemic viral neuraminidase. Only the cross section of the stalk region with two N-linked glycans are depicted for clarity. (A) Carbohydrate–carbohydrate interaction on non-fucosylated monomer allows tetramerization. (B) Core-fucosylation disrupts the interaction and prevents the tetramerization. - Highlights: • Expressed 1918 pandemic influenza viral neuraminidase has inactive and active forms. • The inactive form contains high level of core-6 fucose, while the active form lacks such modification. • Core fucose could interfere the oligomerization of the neuraminidase and thus its activation. • This discovery may

  9. 47 CFR 1.933 - Public notices.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.933 Public notices. (a) Generally. Periodically, the Commission issues Public Notices in the Wireless Radio Services... services shall be placed on Public Notice as accepted for filing prior to grant: (1) Wireless...

  10. 47 CFR 1.933 - Public notices.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.933 Public notices. (a) Generally. Periodically, the Commission issues Public Notices in the Wireless Radio Services... services shall be placed on Public Notice as accepted for filing prior to grant: (1) Wireless...

  11. 47 CFR 1.933 - Public notices.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Wireless Radio Services Applications and Proceedings Application Requirements and Procedures § 1.933 Public notices. (a) Generally. Periodically, the Commission issues Public Notices in the Wireless Radio Services... services shall be placed on Public Notice as accepted for filing prior to grant: (1) Wireless...

  12. 29 CFR 1918.83 - Stowed cargo; tiering and breaking down.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 1918.83 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.83 Stowed... cargo shall be checked in and out by the job boss. Before securing any reefer compartment, a check shall...

  13. [The 1918 influenza epidemic in Bogota].

    PubMed

    Martínez Martín, Abel Fernando; Manrique Abril, Fred Gustavo; Meléndez Alvarez, Bernardo Francisco

    2007-01-01

    The influenza pandemic of 1918-1919 was one of the most severe recorded in Colombia. There were 1,900 deaths in the capital, Bogota. The poor and unprotected were the most affected. Care of victims was the responsibility of the Junta de Socorros, a private body. Based on different primary sources (mostly official documents, Junta de Socorros reports, newspapers, and medical journals) this article explores how the 1918 influenza pandemic altered Bogotá's social dynamics, with particular attention to its impact on disease and mortality rates and to an analysis of how the city's sanitary conditions and political-institutional decisions and the reactions of different social sectors influenced the response of this human community to the pandemic.

  14. Nazi Women Before 1933: Rebels Against Emancipation

    ERIC Educational Resources Information Center

    Koonz, Claudia

    1976-01-01

    The author examines the political affiliation of German women with the past Nazi party before 1933. He discusses why German women supported the anti-feminist Nazi group which showed open contempt for women. (Author/RM)

  15. Seasonal Trivalent Inactivated Influenza Vaccine Protects against 1918 Spanish Influenza Virus Infection in Ferrets

    PubMed Central

    Pearce, Melissa B.; Belser, Jessica A.; Gustin, Kortney M.; Pappas, Claudia; Houser, Katherine V.; Sun, Xiangjie; Maines, Taronna R.; Pantin-Jackwood, Mary J.; Katz, Jacqueline M.

    2012-01-01

    The influenza virus H1N1 pandemic of 1918 was one of the worst medical catastrophes in human history. Recent studies have demonstrated that the hemagglutinin (HA) protein of the 1918 virus and 2009 H1N1 pandemic virus [A(H1N1)pdm09], the latter now a component of the seasonal trivalent inactivated influenza vaccine (TIV), share cross-reactive antigenic determinants. In this study, we demonstrate that immunization with the 2010-2011 seasonal TIV induces neutralizing antibodies that cross-react with the reconstructed 1918 pandemic virus in ferrets. TIV-immunized ferrets subsequently challenged with the 1918 virus displayed significant reductions in fever, weight loss, and virus shedding compared to these parameters in nonimmune control ferrets. Seasonal TIV was also effective in protecting against the lung infection and severe lung pathology associated with 1918 virus infection. Our data demonstrate that prior immunization with contemporary TIV provides cross-protection against the 1918 virus in ferrets. These findings suggest that exposure to A(H1N1)pdm09 through immunization may provide protection against the reconstructed 1918 virus which, as a select agent, is considered to pose both biosafety and biosecurity threats. PMID:22553323

  16. 29 CFR 1918.86 - Roll-on roll-off (Ro-Ro) operations (see also § 1918.2, Ro-Ro operations, and § 1918.25).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., Ro-Ro operations, and § 1918.25). 9 [Reserved] (a) Traffic control system. An organized system of... simultaneous use of the ramp by vehicles and pedestrians. (d) Ramp maintenance. Ramps shall be properly...: (1) Sufficient power to ascend ramp inclines safely; and (2) Sufficient braking capacity to descend...

  17. Structural Characterization of the 1918 Influenza H1N1 Neuraminidase

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, X.; Zhu, X.; Dwek, R.A.

    2009-05-28

    Influenza virus neuraminidase (NA) plays a crucial role in facilitating the spread of newly synthesized virus in the host and is an important target for controlling disease progression. The NA crystal structure from the 1918 'Spanish flu' (A/Brevig Mission/1/18 H1N1) and that of its complex with zanamivir (Relenza) at 1.65-{angstrom} and 1.45-{angstrom} resolutions, respectively, corroborated the successful expression of correctly folded NA tetramers in a baculovirus expression system. An additional cavity adjacent to the substrate-binding site is observed in N1, compared to N2 and N9 NAs, including H5N1. This cavity arises from an open conformation of the 150 loop (Gly147more » to Asp151) and appears to be conserved among group 1 NAs (N1, N4, N5, and N8). It closes upon zanamivir binding. Three calcium sites were identified, including a novel site that may be conserved in N1 and N4. Thus, these high-resolution structures, combined with our recombinant expression system, provide new opportunities to augment the limited arsenal of therapeutics against influenza.« less

  18. Developments in Nursing Education since 1918. Bulletin, 1921, No. 20

    ERIC Educational Resources Information Center

    Stewart, Isabel M.

    1921-01-01

    This bulletin details developments in nursing education since 1918. The following sections are included: (1) The situation in nursing before 1918; (2) The demands of the war and how they were met; (3) Decline in applicants following the war; (4) The work of student nurses in hospitals; (5) Hours of duty in hospitals; (6) Health, recreation, and…

  19. 29 CFR 1918.86 - Roll-on roll-off (Ro-Ro) operations (see also § 1918.2, Ro-Ro operations, and § 1918.25).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., Ro-Ro operations, and § 1918.25). 9 [Reserved] (a) Traffic control system. An organized system of vehicular and pedestrian traffic control shall be established and maintained at each entrance/exit ramp and on ramps within the vessel as traffic flow warrants. (b) Ramp load limit. Each ramp shall be plainly...

  20. 29 CFR 1918.86 - Roll-on roll-off (Ro-Ro) operations (see also § 1918.2, Ro-Ro operations, and § 1918.25).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., Ro-Ro operations, and § 1918.25). 9 [Reserved] (a) Traffic control system. An organized system of vehicular and pedestrian traffic control shall be established and maintained at each entrance/exit ramp and on ramps within the vessel as traffic flow warrants. (b) Ramp load limit. Each ramp shall be plainly...

  1. 29 CFR 1918.86 - Roll-on roll-off (Ro-Ro) operations (see also § 1918.2, Ro-Ro operations, and § 1918.25).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., Ro-Ro operations, and § 1918.25). 9 [Reserved] (a) Traffic control system. An organized system of vehicular and pedestrian traffic control shall be established and maintained at each entrance/exit ramp and on ramps within the vessel as traffic flow warrants. (b) Ramp load limit. Each ramp shall be plainly...

  2. Circulating avian influenza viruses closely related to the 1918 virus have pandemic potential

    PubMed Central

    Watanabe, Tokiko; Zhong, Gongxun; Russell, Colin A.; Nakajima, Noriko; Hatta, Masato; Hanson, Anthony; McBride, Ryan; Burke, David F.; Takahashi, Kenta; Fukuyama, Satoshi; Tomita, Yuriko; Maher, Eileen A.; Watanabe, Shinji; Imai, Masaki; Neumann, Gabriele; Hasegawa, Hideki; Paulson, James C.; Smith, Derek J.; Kawaoka, Yoshihiro

    2014-01-01

    Summary Wild birds harbor a large gene pool of influenza A viruses that have the potential to cause influenza pandemics. Foreseeing and understanding this potential is important for effective surveillance. Our phylogenetic and geographic analyses revealed the global prevalence of avian influenza virus genes whose proteins differ only a few amino acids from the 1918 pandemic influenza virus, suggesting that 1918-like pandemic viruses may emerge in the future. To assess this risk, we generated and characterized a virus composed of avian influenza viral segments with high homology to the 1918 virus. This virus exhibited higher pathogenicity in mice and ferrets than an authentic avian influenza virus. Further, acquisition of seven amino acid substitutions in the viral polymerases and the hemagglutinin surface glycoprotein conferred respiratory droplet transmission to the 1918-like avian virus in ferrets, demonstrating that contemporary avian influenza viruses with 1918 virus-like proteins may have pandemic potential. PMID:24922572

  3. A history of the 1918 Spanish influenza pandemic and its impact on Iran.

    PubMed

    Azizi, Mohammad Hossein; Raees Jalali, Ghanbar Ali; Azizi, Farzaneh

    2010-05-01

    Approximately ninety two years ago, the worst influenza pandemic or "Spanish flu" occurred in 1918, at the end of the First World War (WWI, 1914-1918) which resulted in the deaths of millions of people worldwide. The death toll exceeded the total number of victims of WWI. The 1918 Spanish flu was a deadly, major global event that affected many countries, including Iran. In Iran, it was accompanied by a high mortality rate estimated to be more than one million. However, detailed information on the impact of this outbreak in Iran is scarce. The present paper describes a brief history of the influenza pandemics in the world as well as the spread of the 1918 Spanish flu to Iran.

  4. 29 CFR 1918.69 - Tools.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Cargo Handling Gear and Equipment Other Than Ship's Gear § 1918.69 Tools. (a) General. Employers shall not issue or permit the use of visibly unsafe tools. (b...

  5. Mortality risk factors during the 1918-1919 influenza pandemic in the Australian army.

    PubMed

    Shanks, G Dennis; Mackenzie, Alison; McLaughlin, Ruth; Waller, Michael; Dennis, Peter; Lee, Seung-Eun; Brundage, John F

    2010-06-15

    Understanding the risk of mortality during the 1918-1919 influenza pandemic could inform preparations for a future pandemic. Prospectively collected demographic, hospitalization, and death data from all individuals who served in the Australian Imperial Force from 1914 through 1919 in Europe and the Middle East were abstracted from archived records. Analyses were conducted to determine mortality risk factors. Hospitalization with a respiratory illness during the spring-summer of 1918 protected soldiers from death (odds ratio, 0.37 [95% confidence interval, 0.25-0.53]; P < .001) but not from hospitalization during the fall-winter of 1918-1919. During the fall-winter of 1918-1919, there was a strong inverse relationship between risk of dying of pneumonia-influenza and time in military service. The pneumonia-influenza death rate among men who enlisted in 1918 (6.33 deaths per 100 person-years) was 9 times higher than that among the 1917 enlistment cohort (0.72 deaths per 100 person-years) and >14 times higher than that among the 1916 cohort (0.43 deaths per 100 person-years), 1915 cohort (0.29 deaths per 100 person-years), and 1914 cohort (0.28 deaths per 100 person-years). There was a strong inverse relationship between length of service in the Australian Imperial Force and mortality risk from pneumonia-influenza during the fall-winter of 1918-1919. The protective effect of increased service likely reflected increased acquired immunity to influenza viruses and endemic bacterial strains that caused secondary pneumonia and most of the deaths during the 1918-1919 influenza pandemic.

  6. 29 CFR 1918.103 - Head protection.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.103 Head... National Standards Institute (ANSI) Z89.1-2009, “American National Standard for Industrial Head Protection...

  7. 29 CFR 1918.103 - Head protection.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.103 Head...-2003, “American National Standard for Industrial Head Protection,” which is incorporated by reference...

  8. 29 CFR 1918.103 - Head protection.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.103 Head... National Standards Institute (ANSI) Z89.1-2009, “American National Standard for Industrial Head Protection...

  9. 29 CFR 1918.104 - Foot protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.104 Foot protection. (a) The employer shall ensure that each affected employee wears protective footwear when working... National Standard for Personal Protection—Protective Footwear,” which is incorporated by reference in...

  10. 29 CFR 1918.103 - Head protection.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.103 Head protection. (a) The employer shall ensure that each affected employee wears a protective helmet when working... Personnel Protection—Protective Headwear for Industrial Workers—Requirements,” which is incorporated by...

  11. 29 CFR 1918.103 - Head protection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Personal Protective Equipment § 1918.103 Head protection. (a) The employer shall ensure that each affected employee wears a protective helmet when working... Personnel Protection—Protective Headwear for Industrial Workers—Requirements,” which is incorporated by...

  12. 29 CFR 1918.67 - Notifying the ship's officers before using certain equipment.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false Notifying the ship's officers before using certain equipment. 1918.67 Section 1918.67 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Cargo Handling Gear and Equipment Other Than...

  13. Synoptic and Climatological Analysis of the 1933 Trinidad Hurricane

    NASA Astrophysics Data System (ADS)

    Studwell, A.; Jiang, X.; Li, L.

    2017-12-01

    In June 1933, a Category One hurricane made landfall on the southeastern coast of Trinidad. This was the first and only hurricane to make landfall on the island during modern climate records, i.e., since the middle 19th century. The storm caused thirteen fatalities on Trinidad and yielded $55.1 million (in 2016 dollars) in damage. With twenty named tropical systems, 1933 was the second most active tropical season on record for the Atlantic basin. This is not entirely surprising since there were a developing La Niña over the equatorial Pacific and there was a positive phase on the Atlantic Multidecadal Oscillation in place, both of which are positive factors for an active season for the tropical Atlantic. However, neither of these factors would yield such a southerly track. A preliminary examination of reanalysis data indicated the 500 mb geopotential heights across tropical Atlantic during late June 1933 were well above the 1921-1950 climate normal. This uncharacteristic feature may have contributed to this southerly track and the cyclone's landfall on Trinidad, as the 500 mb winds are a proxy for the hurricane steering flow. Further research is being conducted by examining reanalysis data to determine the statistical likelihood of the anomalous ridge, both in its contemporaneous era, as well as the Climate Change (1981-2010) era.

  14. 29 CFR 1918.84 - Bulling cargo.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Handling Cargo § 1918.84 Bulling cargo. (a) Bulling cargo... from padeyes, straps, or beam clamps. Snatch blocks or straps shall not be made fast to batten cleats...

  15. NORTHWEST FRONT AND SOUTHWEST SIDE, BUILDING 1933 Edwards Air ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    NORTHWEST FRONT AND SOUTHWEST SIDE, BUILDING 1933 - Edwards Air Force Base, X-15 Engine Test Complex, Observation Bunker Types, Rogers Dry Lake, east of runway between North Base & South Base, Boron, Kern County, CA

  16. 29 CFR 1918.54 - Rigging gear.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Vessel's Cargo Handling Gear § 1918.54 Rigging gear. (a... provided, the guys shall be so placed as to produce a minimum stress and not permit the boom to jackknife...

  17. The first wave of the 1918 influenza pandemic among soldiers of the Canadian expeditionary force.

    PubMed

    Rewegan, Alex; Bogaert, Kandace; Yan, Melissa; Gagnon, Alain; Herring, D Ann

    2015-01-01

    This article evaluates the evidence for the presence of the first, mild wave of the 1918 influenza pandemic among soldiers in the Canadian Expeditionary Force (CEF). Death records for soldiers in the CEF who died in Canada in 1917 and 1918 were extracted from the Commonwealth War Graves Commission and record-linked to the Canada War Graves Registers, Circumstances of Casualty database. Monthly mortality rates from pneumonia and influenza (P&I) were compared with mortality rates from all other causes for 1917 and 1918, and by region for 1918. The herald wave of influenza was present among CEF soldiers in 1918. P&I mortality was significantly higher in March and April 1918 than during the same period in 1917. P&I mortality rates varied across the country and were significantly higher among soldiers who died in the Maritime region of Canada. In March, Maritime P&I mortality was significantly higher than its counterpart in the West; in April it was significantly higher than P&I mortality in both the Central and Western regions. The CEF findings suggest that local, geographic heterogeneity characterized the first wave of the 1918 influenza pandemic in Canada and illustrate the ways in which well-established, historical patterns of cross-border social contact with the United States, coupled with the special conditions created by warfare, disproportionately funnelled influenza into particular regions. Identification of the mild first wave among soldiers in the CEF calls for more research on the civilian experience of both waves of influenza in Canada. © 2015 Wiley Periodicals, Inc.

  18. 29 CFR 1918.88 - Log operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... protected by a personal flotation device meeting the requirements of § 1918.105(b)(2). (c) Footwear. The employer shall provide each employee that is working logs with appropriate footwear, such as spiked shoes or caulked sandals, and shall ensure that each employee wears appropriate footwear to climb or walk...

  19. Seasonal trivalent inactivated influenza vaccine protects against 1918 Spanish influenza virus in ferrets

    USDA-ARS?s Scientific Manuscript database

    The influenza H1N1 pandemic of 1918 was one of the worst medical disasters in human history. Recent studies have demonstrated that the hemagglutinin (HA) protein of the 1918 virus and 2009 H1N1 pandemic virus, the latter now a component of the seasonal trivalent inactivated influenza vaccine (TIV),...

  20. Growth in Turkish Positive Basic Sciences, 1933-1966.

    ERIC Educational Resources Information Center

    Ozinonu, A. Kemal

    This study collected data on the measurable qualities of Turkish science in terms of high level scientific manpower, scientific productivity, and scientific fertility from 1933 to 1966 and analyzed the data collected with the goal of providing a deeper understanding of the nature of Turkish science. Scientific personnel, including Turkish…

  1. 19 CFR 19.33 - General order; transportation in bond.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Bonded for the Storage of Wheat § 19.33 General order; transportation in bond. The provisions of §§ 19.29 through 19.32 shall be applicable to those parts of any premises in which imported wheat is stored in a...

  2. 29 CFR 1918.41 - Coaming clearances.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.41 Coaming... five feet (1.52 m) high is stowed within three feet (.91 m) of the hatch coaming and employees handling hatch beams and hatch covers are not protected by a coaming at least 24-inch (.61 m) high, a taut...

  3. 29 CFR 1918.41 - Coaming clearances.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.41 Coaming... five feet (1.52 m) high is stowed within three feet (.91 m) of the hatch coaming and employees handling hatch beams and hatch covers are not protected by a coaming at least 24-inch (.61 m) high, a taut...

  4. 29 CFR 1918.41 - Coaming clearances.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.41 Coaming... five feet (1.52 m) high is stowed within three feet (.91 m) of the hatch coaming and employees handling hatch beams and hatch covers are not protected by a coaming at least 24-inch (.61 m) high, a taut...

  5. 29 CFR 1918.41 - Coaming clearances.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.41 Coaming... five feet (1.52 m) high is stowed within three feet (.91 m) of the hatch coaming and employees handling hatch beams and hatch covers are not protected by a coaming at least 24-inch (.61 m) high, a taut...

  6. 29 CFR 1918.41 - Coaming clearances.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING Opening and Closing Hatches § 1918.41 Coaming... five feet (1.52 m) high is stowed within three feet (.91 m) of the hatch coaming and employees handling hatch beams and hatch covers are not protected by a coaming at least 24-inch (.61 m) high, a taut...

  7. The Spanish influenza pandemic in occidental Europe (1918–1920) and victim age

    PubMed Central

    Erkoreka, Anton

    2010-01-01

    Please cite this paper as: Erkoreka A. (2010) The Spanish influenza pandemic in occidental Europe (1918–1920) and victim age. Influenza and Other Respiratory Viruses 4(2), 81–89. Background  Studies of the Spanish Influenza pandemic (1918–1920) provide interesting information that may improve our preparation for present and future influenza pandemic threats. Methods  We studied archives from France, Italy, Spain and Portugal, obtaining high‐quality data that allowed us to calculate mortality rates associated with the Spanish flu and to characterize the proportional distribution of influenza deaths by age in the capital cities of these countries. Results  French and American troops who fought in the First World War began to be affected from April 1918 onwards by a benign influenza epidemic, which hardly caused any deaths. The first occidental European country in which the pandemic spread to large sectors of the population, causing serious mortality, was Spain. The associated influenza provoked in Madrid a mortality rate of 1·31 per 1000 inhabitants between May and June (1918). In the following months of June and July, the epidemic spread to Portugal, but did not reach the Pyrenees. In September 1918, the influenza pandemic spread with tremendous virulence, presenting itself simultaneously during the month of October in South Western European countries. In Madrid, the 1918 excess mortality due in large part to the influenza pandemic is estimated at 5·27 per 1000. In Paris, the 1918 mortality rate provoked by the influenza and pathologies of the respiratory system was 6·08 per 1000. In South Western European countries, mortality rates oscillated between 10·6 and 12·1 per 1000 inhabitants. A study of the age distribution of deaths due to influenza between 1916 and 1921 reveals that the Spanish influenza principally affected men and women between 15 and 44 years of age. Deaths associated with the seasonal influenza of 1916, 1917 and 1921 represented

  8. 29 CFR 1918.3 - Incorporation by reference.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Archives and Records Administration (NARA). For information on the availability of this material at NARA..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1918.104(b)(1....org. (5) ANSI Z41-1991, American National Standard for Personal Protection—Protective Footwear; IBR...

  9. 29 CFR 1918.3 - Incorporation by reference.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Archives and Records Administration (NARA). For information on the availability of this material at NARA..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1918.104(b)(1....org. (5) ANSI Z41-1991, American National Standard for Personal Protection—Protective Footwear; IBR...

  10. 29 CFR 1918.3 - Incorporation by reference.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Archives and Records Administration (NARA). For information on the availability of this material at NARA..., American National Standard for Personal Protection—Protective Footwear; IBR approved for § 1918.104(b)(1....org. (5) ANSI Z41-1991, American National Standard for Personal Protection—Protective Footwear; IBR...

  11. 17 CFR 239.18 - Form S-11, for registration under the Securities Act of 1933 of securities of certain real estate...

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... under the Securities Act of 1933 of securities of certain real estate companies. 239.18 Section 239.18... Securities Act of 1933 of securities of certain real estate companies. This form shall be used for registration under the Securities Act of 1933 of (a) securities issued by real estate investment trusts, as...

  12. 17 CFR 239.18 - Form S-11, for registration under the Securities Act of 1933 of securities of certain real estate...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under the Securities Act of 1933 of securities of certain real estate companies. 239.18 Section 239.18... Securities Act of 1933 of securities of certain real estate companies. This form shall be used for registration under the Securities Act of 1933 of (a) securities issued by real estate investment trusts, as...

  13. 37. Mass meeting held July 9th, 1918, in warehouse no.2 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    37. Mass meeting held July 9th, 1918, in warehouse no.2 on the Fleet Supply Base, Brooklyn, New York col Americo Pio is speaking in Italian. View depicts one of the activities mounted by Turner Construction Company to stimulates labor enthusiasm during its 1918 construction projects for the U.S. Navy and U.s. Army. - U.S. Navy Fleet Supply Base, Storehouse No. 1, 830 Third Avenue, Brooklyn, Kings County, NY

  14. A History of Adult Education in Germany (1800-1933).

    ERIC Educational Resources Information Center

    Pirtle, Wayne George

    German adult education before 1933 stressed group experience in the family, clan, and culture rather than knowledge and the individual. Outside trends, expecially in England, Austria, Denmark, and the United States, repeatedly influenced the German movement. While lecture institutes, university extension, and other activities were important, the…

  15. Bird flu, influenza and 1918: the case for mutant Avian tuberculosis.

    PubMed

    Broxmeyer, Lawrence

    2006-01-01

    Influenza is Italian for "influence", Latin: influentia. It used to be thought that the disease was caused by a bad influence from the heavens. Influenza was called a virus long, long before it was proven to be one. In 2005, an article in the New England Journal of Medicine estimated that a recurrence of the 1918 influenza epidemic could kill between 180 million and 360 million people worldwide. A large part of the current bird-flu hysteria is fostered by a distrust among the lay and scientific community regarding the actual state of our knowledge regarding the bird flu or H5N1 and the killer "Influenza" Pandemic of 1918 that it is compared to. And this distrust is not completely unfounded. Traditionally, "flu" does not kill. Experts, including Peter Palese of the Mount School of Medicine in Manhattan, remind us that even in 1992, millions in China already had antibodies to H5N1, meaning that they had contracted it and that their immune system had little trouble fending it off. Dr. Andrew Noymer and Michel Garenne, UC Berkely demographers, reported in 2000 convincing statistics showing that undetected tuberculosis may have been the real killer in the 1918 flu epidemic. Aware of recent attempts to isolate the "Influenza virus" on human cadavers and their specimens, Noymer and Garenne summed that: "Frustratingly, these findings have not answered the question why the 1918 virus was so virulent, nor do they offer an explanation for the unusual age profile of deaths". Bird flu would certainly be diagnosed in the hospital today as Acute Respiratory Distress Syndrome (ARDS). Roger and others favor suspecting tuberculosis in all cases of acute respiratory failure of unknown origin. By 1918, it could be said, in so far as tuberculosis was concerned, that the world was a supersaturated sponge ready to ignite and that among its most vulnerable parts was the very Midwest where the 1918 unknown pandemic began. It is theorized that the lethal pig epidemic that began in Kansas

  16. Historic American Buildings Survey, A.S. Burns, Photographer December, 1933 HOUSE ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Historic American Buildings Survey, A.S. Burns, Photographer December, 1933 HOUSE IN PENNSYLVANIA - Structures on Old National Trail, House in Pennsylvania, U.S. Route 40, Pittsburgh, Allegheny County, PA

  17. Historic American Buildings Survey, A.S. Burns, Photographer December, 1933 DETAIL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Historic American Buildings Survey, A.S. Burns, Photographer December, 1933 DETAIL OF BRIDGE IN PENNSYLVANIA - Structures on Old National Trail, Bridge, U.S. Route 40, Pittsburgh, Allegheny County, PA

  18. Frances Keesler Graham (1918-2013).

    PubMed

    Berg, W Keith

    2014-09-01

    Frances Keesler Graham, noted psychophysiologist and developmental researcher, died on April 16, 2013. Fran was born in Canastota, New York, on August 1, 1918. Fran's high-quality research, her success in obtaining 39 years of uninterrupted funding, and the very high regard in which she was held among her colleagues led to numerous awards and honors. Fran was demanding but equally willing to provide extensive assistance to students willing to work hard. (c) 2014 APA, all rights reserved.

  19. 7. Photographic copy of photograph (ca. 1933), original print and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. Photographic copy of photograph (ca. 1933), original print and negative in possession of Selfridge Base Museum, Mt. Clemens, Michigan. NORTHWEST VIEW BAKING ROOM INTERIOR - Selfridge Field, Building No. 129, Wilbur Wright Boulevard at Ash Street, Mount Clemens, Macomb County, MI

  20. A Study of How Letters to the Editor Published in "The Stars and Stripes" Newspaper between March 1, 1918, and November 15, 1918, Reflected the Morale of the Troops during World War I

    ERIC Educational Resources Information Center

    Hatch, Vicky Ann

    2009-01-01

    This dissertation is a qualitative historical study that examines the state of morale of World War I soldiers as reflected in letters to the editor published in "The Stars and Stripes" newspaper between March 1, 1918, and November 15, 1918. The narrative includes extensive use of the actual words published in the soldiers' letters in order to…

  1. Historic American Buildings Survey, A.S. Burns, Photographer December, 1933 TOLL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Historic American Buildings Survey, A.S. Burns, Photographer December, 1933 TOLL HOUSE (DETAIL OF PLAQUE SHOWING TOLL RATES) - Structures on Old National Trail, Toll House, U.S. Route 40, Pittsburgh, Allegheny County, PA

  2. 49. Photocopy of photograph, October 22, 1933. VIEW OF POWER ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    49. Photocopy of photograph, October 22, 1933. VIEW OF POWER HOUSE, FOREBAY AND RIVER. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  3. Divorce and suicide: a time series analysis, 1933-1970.

    PubMed

    Stack, S

    1981-01-01

    The author examines the relationship between divorce and suicide using U.S. data for the period 1933-1970. The increase in the strength of the positive relationship between divorce and suicide in the period after World War II is contrasted with trends during the era of the Depression preceding World War II

  4. No evidence of 1918 influenza pandemic origin in Chinese laborers/soldiers in France.

    PubMed

    Shanks, G Dennis

    2016-01-01

    Laborers and soldiers from China and Southeast Asia recruited during the First World War by Britain and France have been suggested as the origin of the 1918 influenza pandemic in Western Europe. This study aimed to review the available data to better understand the sources and origins of the 1918 influenza pandemic, and clarify whether, in fact, there was an Asian connection to its onset. We reviewed official mortality lists from the Commonwealth War Graves Commission and the French Ministry of Defence for all-cause (Britain) and pneumonia/influenza (France) mortality, respectively. The results indicated that influenza mortality (estimated 1/1000) in Chinese and Southeast Asian laborers and soldiers lagged other co-located military units by several weeks. This finding does not support a Southeast Asian importation of lethal influenza to Europe in 1918. Copyright © 2015. Published by Elsevier Taiwan LLC.

  5. 12 CFR 250.220 - Whether member bank acting as trustee is prohibited by section 20 of the Banking Act of 1933 from...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... prohibited by section 20 of the Banking Act of 1933 from acquiring majority of shares of mutual fund. 250.220... trustee is prohibited by section 20 of the Banking Act of 1933 from acquiring majority of shares of mutual fund. (a) The Board recently considered whether section 20 of the Banking Act of 1933 (12 U.S.C. 377...

  6. 12 CFR 250.220 - Whether member bank acting as trustee is prohibited by section 20 of the Banking Act of 1933 from...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... prohibited by section 20 of the Banking Act of 1933 from acquiring majority of shares of mutual fund. 250.220... trustee is prohibited by section 20 of the Banking Act of 1933 from acquiring majority of shares of mutual fund. (a) The Board recently considered whether section 20 of the Banking Act of 1933 (12 U.S.C. 377...

  7. 4. Historic American Buildings Survey, A.S. Burns, Photographer November, 1933 ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    4. Historic American Buildings Survey, A.S. Burns, Photographer November, 1933 OLD COVERED BRIDGE (SEVEN MILES FROM ZANESVILLE). - Old Covered Bridge, West of Zanesville Post Office, U.S. Highway 40, Hopewell, Muskingum County, OH

  8. Deaths from bacterial pneumonia during 1918-19 influenza pandemic.

    PubMed

    Brundage, John F; Shanks, G Dennis

    2008-08-01

    Deaths during the 1918-19 influenza pandemic have been attributed to a hypervirulent influenza strain. Hence, preparations for the next pandemic focus almost exclusively on vaccine prevention and antiviral treatment for infections with a novel influenza strain. However, we hypothesize that infections with the pandemic strain generally caused self-limited (rarely fatal) illnesses that enabled colonizing strains of bacteria to produce highly lethal pneumonias. This sequential-infection hypothesis is consistent with characteristics of the 1918-19 pandemic, contemporaneous expert opinion, and current knowledge regarding the pathophysiologic effects of influenza viruses and their interactions with respiratory bacteria. This hypothesis suggests opportunities for prevention and treatment during the next pandemic (e.g., with bacterial vaccines and antimicrobial drugs), particularly if a pandemic strain-specific vaccine is unavailable or inaccessible to isolated, crowded, or medically underserved populations.

  9. 403. Delineator Unknown May 2, 1933 STUDY FOR SUSPENSION TOWERS; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    403. Delineator Unknown May 2, 1933 STUDY FOR SUSPENSION TOWERS; SAN FRANCISCO - OAKLAND BAY BRIDGE; TIMOTHY L. PFLUEGER, ARTHUR BROWN JR., JOHN J. DONOVAN; BOARD OF CONSULTING ARCHITECTS; SCHEME 2 - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  10. Spatial-temporal excess mortality patterns of the 1918–1919 influenza pandemic in Spain

    PubMed Central

    2014-01-01

    Background The impact of socio-demographic factors and baseline health on the mortality burden of seasonal and pandemic influenza remains debated. Here we analyzed the spatial-temporal mortality patterns of the 1918 influenza pandemic in Spain, one of the countries of Europe that experienced the highest mortality burden. Methods We analyzed monthly death rates from respiratory diseases and all-causes across 49 provinces of Spain, including the Canary and Balearic Islands, during the period January-1915 to June-1919. We estimated the influenza-related excess death rates and risk of death relative to baseline mortality by pandemic wave and province. We then explored the association between pandemic excess mortality rates and health and socio-demographic factors, which included population size and age structure, population density, infant mortality rates, baseline death rates, and urbanization. Results Our analysis revealed high geographic heterogeneity in pandemic mortality impact. We identified 3 pandemic waves of varying timing and intensity covering the period from Jan-1918 to Jun-1919, with the highest pandemic-related excess mortality rates occurring during the months of October-November 1918 across all Spanish provinces. Cumulative excess mortality rates followed a south–north gradient after controlling for demographic factors, with the North experiencing highest excess mortality rates. A model that included latitude, population density, and the proportion of children living in provinces explained about 40% of the geographic variability in cumulative excess death rates during 1918–19, but different factors explained mortality variation in each wave. Conclusions A substantial fraction of the variability in excess mortality rates across Spanish provinces remained unexplained, which suggests that other unidentified factors such as comorbidities, climate and background immunity may have affected the 1918–19 pandemic mortality rates. Further archeo

  11. 402. Delineator Unknown May 2, 1933 STUDY FOR SUSPENSION TOWERS; ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    402. Delineator Unknown May 2, 1933 STUDY FOR SUSPENSION TOWERS; SAN FRANCISCO - OAKLAND BAY BRIDGE; TIMOTHY L. PFLUEGER, ARTHUR BROWN JR., JOHN J. DONOVAN; BOARD OF CONSULTING ARCHITECTS; SCHEME 1A - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  12. 10 CFR 19.18 - Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 10 Energy 1 2011-01-01 2011-01-01 false Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena. 19.18 Section 19.18 Energy NUCLEAR REGULATORY COMMISSION NOTICES... supporting the decision to exclude. This statement, which must be provided no later than five working days...

  13. 10 CFR 19.18 - Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 10 Energy 1 2012-01-01 2012-01-01 false Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena. 19.18 Section 19.18 Energy NUCLEAR REGULATORY COMMISSION NOTICES... supporting the decision to exclude. This statement, which must be provided no later than five working days...

  14. 10 CFR 19.18 - Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 10 Energy 1 2013-01-01 2013-01-01 false Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena. 19.18 Section 19.18 Energy NUCLEAR REGULATORY COMMISSION NOTICES... supporting the decision to exclude. This statement, which must be provided no later than five working days...

  15. 10 CFR 19.18 - Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena. 19.18 Section 19.18 Energy NUCLEAR REGULATORY COMMISSION NOTICES... supporting the decision to exclude. This statement, which must be provided no later than five working days...

  16. 10 CFR 19.18 - Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 10 Energy 1 2014-01-01 2014-01-01 false Sequestration of witnesses and exclusion of counsel in interviews conducted under subpoena. 19.18 Section 19.18 Energy NUCLEAR REGULATORY COMMISSION NOTICES... supporting the decision to exclude. This statement, which must be provided no later than five working days...

  17. 56. Neg. No. F161, Mar 18, 1933, INTERIOROFFICE BUILDING, LOBBY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    56. Neg. No. F-161, Mar 18, 1933, INTERIOR-OFFICE BUILDING, LOBBY AND STAIRWELL, SHOWING DAMAGE AFTER AN EARTHQUAKE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  18. 44. Photocopy of photograph, October 20, 1933. VIEW OF FOREBAY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    44. Photocopy of photograph, October 20, 1933. VIEW OF FOREBAY AND INLET OPENINGS, NOTE SLUICE GATE AND DAM AT LOWER RIGHT. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing) - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  19. 404. Delineator Unknown June 1, 1933 STUDY FOR TOP OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    404. Delineator Unknown June 1, 1933 STUDY FOR TOP OF SUSPENSION TOWERS; SAN FRANCISCO OAKLAND BAY BRIDGE; TIMOTHY L. PFLUEGER, ARTHUR BROWN JR., JOHN J. DONOVAN; BOARD OF CONSULTING ARCHITECTS; SCHEME 7-A - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  20. 26. Photocopy of August 1918 photograph. Glass Negative Box IX, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    26. Photocopy of August 1918 photograph. Glass Negative Box IX, Tower Grove, Missouri Botanical Garden. ITALIAN GARDEN, LOOKING SOUTHWEST - Missouri Botanical Garden, 2345 Tower Grove Avenue, Saint Louis, Independent City, MO

  1. 21. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    21. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) ERECTION PLAN-PIER NO. 4 - Brooklyn Army Supply Base, Pier 4, Brooklyn, Kings County, NY

  2. Astronomy in Denver: Centenary of the 1918 total solar eclipse across Denver

    NASA Astrophysics Data System (ADS)

    Stencel, Robert E.

    2018-06-01

    Totality during the 2017 August 21 solar eclipse (Saros 145) traveled along a path across the United States similar to that which occurred for the eclipse on 1918 June 8 (Saros 126), but with a less west-northerly track. This placed Denver and its then new Chamberlin Observatory in the path of totality. Denver University astronomy Professor Herbert Howe offered use of the Chamberlin Observatory 20-inch f/15 refractor, with its Clark doublet lens and Saegmueller mounting, in service of eclipse-related research. In preparation for the eclipse, Professor Howe and assistants had spent the last three months of 1917, refurbishing mechanical aspects of the telescope. Edwin Frost, then Director of Yerkes Observatory expressed interest and made a reconnaissance visit to the area in September 1917, reporting results in the Feb. 1918 issue of Popular Astronomy ( http://adsabs.harvard.edu/abs/1918PA.....26R.103F ). Frank Schlesinger, then director of Allegheny Observatory, asked if he might attach a special camera for star photography to the telescope at the eclipse, to test displacement of stars, in order to test a prediction of relativity theory. Among the additional visiting astronomical luminaries present on that June day in 1918 were Annie J. Cannon (Harvard), John Duncan (Wellesley), Herbert R. Morgan (U.S. Naval Observatory) and Robert Trumpler (Berkeley). To learn the results of all this eclipse preparedness, you will need to attend my talk in order to get “the rest of the story” or visit our twitter feed at: https://twitter.com/Chamberlin_Obs .

  3. [Serums and vaccines to fight the 1918-1919 influenza pandemic in Spain].

    PubMed

    Porras Gallo, M I

    2008-01-01

    Against the background of the renewed interest aroused in recent years by the influenza pandemic of 1918-1919, and the leading role now played by research analysing the process of innovation in medicine, this paper assesses the role played by serums and vaccines - the new resources of the medical science of the time 0 in the fight against the influenza outbreak of 1918-1919. The paper highlights the dependence on combined scientific, social, economic and professional factors, and also shows the main consequences arising from the fine-tuning and implementation of these therapeutic and prophylactic resources.

  4. 19. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    19. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) BRIDGES BETWEEN WAREHOUSE A AND PIERS - Brooklyn Army Supply Base, Pier 2, Brooklyn, Kings County, NY

  5. 390. Delineator Unknown October 1933 STATE OF CALIFORNIA; DEPARTMENT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    390. Delineator Unknown October 1933 STATE OF CALIFORNIA; DEPARTMENT OF PUBLIC WORKS; SAN FRANCISCO - OAKLAND BAY BRIDGE; SUPERSTRUCTURE - EAST BAY CROSSING; SPANS YBI TO El - E9 TO El ; TYPICAL CROSSSECTION; CONTRACT NO. 7; SUP. DRAWING NO. 82 - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  6. 15. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) TYPICAL DETAILS-PIERS 2, 3, AND 4 - Brooklyn Army Supply Base, Pier 2, Brooklyn, Kings County, NY

  7. 13. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    13. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) ARMY SUPPLY BASE-PLAN OF CONSTRUCTION PLANT - Brooklyn Army Supply Base, Pier 2, Brooklyn, Kings County, NY

  8. 14. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    14. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) SECTIONS AND DETAILS-PIERS 2, 3, AND 4 - Brooklyn Army Supply Base, Pier 2, Brooklyn, Kings County, NY

  9. Not a slippery slope or sudden subversion: German medicine and national socialism in 1933.

    PubMed

    Hanauske-Abel, H M

    1996-12-07

    The history of medicine this century is darkened by the downfall of the German medical profession, exposed during the doctors' trial at Nuremberg in 1946. Relying largely on documents published during 1933 in German medical journals, this paper examines two widely accepted notions of those events, metaphorically termed "slippery slope" and "sudden subversion." The first connotes a gradual slide over infinitesimal steps until, suddenly, all footing is lost; the second conveys forced take over of the profession's leadership and values. Both concepts imply that the medical profession itself became the victim of circumstances. The slippery slope concept is a prominent figure of argument in the current debate on bioethics. The evidence presented here, however, strongly suggests that the German medical community set its own course in 1933. In some respects this course even outpaced the new government, which had to rein in the profession's eager pursuit of enforced eugenic sterilizations. In 1933 the convergence of political, scientific, and economic forces dramatically changed the relationship between the medical community and the government. That same convergence is occurring again and must be approached with great caution if medicine is to remain focused on the preservation of physical and medical integrity.

  10. 58. Neg. No. F160a, Jan 11, 1933, INTERIOROFFICE BUILDING/ ASSEMBLY ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    58. Neg. No. F-160a, Jan 11, 1933, INTERIOR-OFFICE BUILDING/ ASSEMBLY BUILDING, FIRST AID ROOM - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  11. 15. Photographic copy of construction drawing, dated June 7, 1933, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    15. Photographic copy of construction drawing, dated June 7, 1933, Construction Division Office of the Quartermaster General, in possession of Selfridge Base Museum, Mt. Clemens, Michigan. PLAN 625-25??, SDO 134 F4 1B (ELEVATIONS) - Selfridge Field, Building Nos. 242, 247, 250, 242 & 247 Birch Street & 250 Wagner Street, Mount Clemens, Macomb County, MI

  12. 12. Photographic copy of construction drawing, dated June 7, 1933, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    12. Photographic copy of construction drawing, dated June 7, 1933, Construction Division Office of the Quartermaster General, in possession of Selfridge Base Museum, Mt. Clemens, Michigan. PLAN 625-2517, SDO 186 F41 (FLOOR PLAN) - Selfridge Field, Building Nos. 248, 252 & 254, 248 Birch Street & 252, 254 Wagner Street, Mount Clemens, Macomb County, MI

  13. 16. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    16. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) DETAILS OF INSHORE ENDS-PIERS 2, 3, AND 4 - Brooklyn Army Supply Base, Pier 2, Brooklyn, Kings County, NY

  14. 17. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    17. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) DETAILS OF OUTSHORE ENDS-PIERS 2, 3, AND 4 - Brooklyn Army Supply Base, Pier 2, Brooklyn, Kings County, NY

  15. Death from 1918 pandemic influenza during the First World War: a perspective from personal and anecdotal evidence

    PubMed Central

    Wever, Peter C; van Bergen, Leo

    2014-01-01

    The Meuse-Argonne offensive, a decisive battle during the First World War, is the largest frontline commitment in American military history involving 1·2 million U.S. troops. With over 26 000 deaths among American soldiers, the offensive is considered “America's deadliest battle”. The Meuse-Argonne offensive coincided with the highly fatal second wave of the influenza pandemic in 1918. In Europe and in U.S. Army training camps, 1918 pandemic influenza killed around 45 000 American soldiers making it questionable which battle should be regarded “America's deadliest”. The origin of the influenza pandemic has been inextricably linked with the men who occupied the military camps and trenches during the First World War. The disease had a profound impact, both for the military apparatus and for the individual soldier. It struck all the armies and might have claimed toward 100 000 fatalities among soldiers overall during the conflict while rendering millions ineffective. Yet, it remains unclear whether 1918 pandemic influenza had an impact on the course of the First World War. Still, even until this day, virological and bacteriological analysis of preserved archived remains of soldiers that succumbed to 1918 pandemic influenza has important implications for preparedness for future pandemics. These aspects are reviewed here in a context of citations, images, and documents illustrating the tragic events of 1918. PMID:24975798

  16. 18. Photocopy of original drawing by Cass Gilbert, 1918 (original ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    18. Photocopy of original drawing by Cass Gilbert, 1918 (original in possession of NYC Economic Development Corp.) PLANS AND SECTIONS, MECHANICAL EQUIPMENT-PIERS 2, 3, AND 4 - Brooklyn Army Supply Base, Pier 2, Brooklyn, Kings County, NY

  17. Draft Genome Sequences of Historical Listeria monocytogenes from Human Listeriosis, 1933

    USDA-ARS?s Scientific Manuscript database

    We report here the draft genome sequences of two Listeria monocytogenes strains from some of the earliest reported cases of human listeriosis in North America. The strains were isolated in 1933 from patients in Massachusetts and Connecticut, USA, and belong to the widely disseminated hypervirulent c...

  18. 5. Photographic copy of construction drawing, dated December 13, 1933, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    5. Photographic copy of construction drawing, dated December 13, 1933, Construction Service QMC, Office of the Constructing Quartermaster, in possession of Selfridge Base Museum, Mt. Clemens, Michigan. ELEVATIONS AND PLAN, PLAN NO. 6658-1, DRAWING 6658-1, DRAWING 6658-242. - Selfridge Field, Building No. 156, Railroad Avenue at North Jefferson Avenue, Mount Clemens, Macomb County, MI

  19. 1918 pandemic morbidity: The first wave hits the poor, the second wave hits the rich.

    PubMed

    Mamelund, Svenn-Erik

    2018-05-01

    Whether morbidity from the 1918-19 influenza pandemic discriminated by socioeconomic status has remained a subject of debate for 100 years. In lack of data to study this issue, the recent literature has hypothesized that morbidity was "socially neutral." To study the associations between influenza-like illness (ILI) and socioeconomic status (SES), gender, and wave during the 1918-19 influenza pandemic. Availability of incidence data on the 1918-19 pandemic is scarce, in particular for waves other than the "fall wave" October-December 1918. Here, an overlooked survey from Bergen, Norway (n = 10 633), is used to study differences in probabilities of ILI and ILI probability ratios by apartment size as a measure of SES and gender for 3 waves including the waves prior to and after the "fall wave." Socioeconomic status was negatively associated with ILI in the first wave, but positively associated in the second wave. At all SES levels, men had the highest ILI in the summer, while women had the highest ILI in the fall. There were no SES or gender differences in ILI in the winter of 1919. For the first time, it is documented a crossover in the role of socioeconomic status in 1918 pandemic morbidity. The poor came down with influenza first, while the rich with less exposure in the first wave had the highest morbidity in the second wave. The study suggests that the socioeconomically disadvantaged should be prioritized if vaccines are of limited availability in a future pandemic. © 2018 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

  20. Enhanced risk of illness during the 1918 influenza pandemic after previous influenza-like illnesses in three military populations.

    PubMed

    Shanks, G D; Burroughs, S A; Sohn, J D; Waters, N C; Smith, V F; Waller, M; Brundage, J F

    2016-07-01

    The reasons for the unprecedented mortality during the 1918 influenza pandemic remain poorly understood. We examined morbidity records from three military cohorts from years prior to and during the 1918 pandemic period to assess the effects of previous respiratory illnesses on experiences during the pandemic. Clinical registers and morbidity lists were examined to identify all medical encounters for acute respiratory illnesses in students at two U.S. military officer training academies and Australian soldiers deployed in Europe. Influenza-like illness prior to the major pandemic wave of 1918 predisposed Australian soldiers [relative risk (RR) 1·37, 95% confidence interval (CI) 1·18-1·60, P < 0·0001] and US officer trainees at West Point (RR 3·10, 95% CI 2·13-4·52, P < 0·0001) and Annapolis (RR 2·03, 95% CI 1·65-2·50, P < 0·0001) to increased risks of medically treated illnesses in late 1918. The findings suggest that susceptibility to and/or clinical expressions of the 1918 pandemic influenza virus depended on previous experiences with respiratory infectious agents. The findings are consistent with observations during the 2009 pandemic in Canada and may reflect antibody-dependent enhancement of influenza infection.

  1. 29 CFR 1918.99 - Retention of DOT markings, placards and labels.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... ADMINISTRATION, DEPARTMENT OF LABOR (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR LONGSHORING General Working Conditions. § 1918.99 Retention of DOT markings, placards and labels. (a) Any employer who receives a package...

  2. Konstantin Gringauz (1918-1993)

    NASA Astrophysics Data System (ADS)

    Konstantin Gringauz of the Space Research Institute in Moscow died on June 10 of a heart attack. A pioneer of the space age, his professional legacy includes many important contributions to the broad field of space research during the past 4 decades.Born in Tula in southeast Russia in 1918, he was the son of a pharmacist. In 1947, he moved to a laboratory in Sergei Korolev's new Bureau for Rocket Development. A year later, he participated for the first time in the launching of a V-2 rocket, which carried his radio probe to study the ionosphere. In 1949, he received his Ph.D. and was put in charge of Korolev's laboratory for radio technology. In 1956, he began designing instruments.

  3. Surface rupture of the 1933 M 7.5 Diexi earthquake in eastern Tibet: implications for seismogenic tectonics

    NASA Astrophysics Data System (ADS)

    Ren, Junjie; Xu, Xiwei; Zhang, Shimin; Yeats, Robert S.; Chen, Jiawei; Zhu, Ailan; Liu, Shao

    2018-03-01

    The 1933 M 7.5 Diexi earthquake is another catastrophic event with the loss of over 10 000 lives in eastern Tibet comparable to the 2008 Mw 7.9 Wenchuan earthquake. Because of its unknown surface rupture, the seismogenic tectonics of the 1933 earthquake remains controversial. We collected unpublished reports, literatures and old photos associated with the 1933 earthquake and conducted field investigations based on high-resolution Google Earth imagery. Combined with palaeoseismological analysis, radiocarbon dating and relocated earthquakes, our results demonstrate that the source of the 1933 earthquake is the northwest-trending Songpinggou fault. This quake produced a > 30 km long normal-faulting surface rupture with the coseismic offset of 0.9-1.7 m. Its moment magnitude (Mw) is ˜6.8. The Songpinggou fault undergoes an average vertical slip rate of ˜0.25 mm yr-1 and has a recurrence interval of ˜6700 yr of large earthquakes. The normal-faulting surface rupture of this quake is probably the reactivation of the Mesozoic Jiaochang tectonic belt in gravitational adjustment of eastern Tibet. Besides the major boundary faults, minor structures within continental blocks may take a role in strain partitioning of eastern Tibet and have the potential of producing large earthquake. This study contributes to a full understanding of seismotectonics of large earthquakes and strain partitioning in eastern Tibet.

  4. 46. Photocopy of photograph, c. 1933. VIEW OF DAM AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    46. Photocopy of photograph, c. 1933. VIEW OF DAM AND FOREBAY. NOTE ALL WATER FLOWING THROUGH FOREBAY AND OUT EITHER TAILRACE OR SLUICE GATE (INSTEAD OF OVER DAM) BECAUSE OF LOW WATER FLOW. (Courtesy of the Potomac Edison Company Library (Hagerstown, MD), Historical Data Files, Dam No. 5 listing - Dam No. 5 Hydroelectric Plant, On Potomac River, Hedgesville, Berkeley County, WV

  5. Death from 1918 pandemic influenza during the First World War: a perspective from personal and anecdotal evidence.

    PubMed

    Wever, Peter C; van Bergen, Leo

    2014-09-01

    The Meuse-Argonne offensive, a decisive battle during the First World War, is the largest frontline commitment in American military history involving 1.2 million U.S. troops. With over 26,000 deaths among American soldiers, the offensive is considered "America's deadliest battle". The Meuse-Argonne offensive coincided with the highly fatal second wave of the influenza pandemic in 1918. In Europe and in U.S. Army training camps, 1918 pandemic influenza killed around 45,000 American soldiers making it questionable which battle should be regarded "America's deadliest". The origin of the influenza pandemic has been inextricably linked with the men who occupied the military camps and trenches during the First World War. The disease had a profound impact, both for the military apparatus and for the individual soldier. It struck all the armies and might have claimed toward 100 000 fatalities among soldiers overall during the conflict while rendering millions ineffective. Yet, it remains unclear whether 1918 pandemic influenza had an impact on the course of the First World War. Still, even until this day, virological and bacteriological analysis of preserved archived remains of soldiers that succumbed to 1918 pandemic influenza has important implications for preparedness for future pandemics. These aspects are reviewed here in a context of citations, images, and documents illustrating the tragic events of 1918. © 2014 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.

  6. [The flu far and near: comparing the 1918 and 2009 pandemics].

    PubMed

    Alvarez, Adriana; Carbonetti, Adrián; Carrillo, Ana María; Bertolli Filho, Claudio; Souza, Christiane Maria Cruz de; Bertucci, Liane Maria; Azevedo, Nara

    2009-01-01

    In this debate, Latin American historians compare the 1918-1919 flu pandemic with the one sweeping the continent in 2009, focusing especially on the experiences in Mexico, Argentina, and Brazil. They analyze the strategies adopted on both occasions, above all isolation measures, port and airport surveillance, and urban interventions. Comparisons are drawn between the actions of federal and local governments, positions taken by doctors and the media, and people's behavior, particularly regarding fear and death. The debaters also analyze the performance of assistance structures, the treatment and prevention measures recommended by public health agencies and private groups with a vested interest in drug sales, and popular and home remedies. The debate extends to how the 1918 experience has influenced the evaluation of today's crisis and what legacy it may leave behind.

  7. 57. Neg. No. F161D, Mar 18, 1933, INTERIORPRESSED STEEL AND ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    57. Neg. No. F-161D, Mar 18, 1933, INTERIOR-PRESSED STEEL AND WAREHOUSE BUILDINGS, 1ST FLOOR, SHOWING DAMAGE TO FREIGHT ELEVATOR SHAFT FROM EARTHQUAKE - Ford Motor Company Long Beach Assembly Plant, Assembly Building, 700 Henry Ford Avenue, Long Beach, Los Angeles County, CA

  8. Influenza and Pneumonia Mortality in 66 Large Cities in the United States in Years Surrounding the 1918 Pandemic

    PubMed Central

    Acuna-Soto, Rodolfo; Viboud, Cécile; Chowell, Gerardo

    2011-01-01

    The 1918 influenza pandemic was a major epidemiological event of the twentieth century resulting in at least twenty million deaths worldwide; however, despite its historical, epidemiological, and biological relevance, it remains poorly understood. Here we examine the relationship between annual pneumonia and influenza death rates in the pre-pandemic (1910–17) and pandemic (1918–20) periods and the scaling of mortality with latitude, longitude and population size, using data from 66 large cities of the United States. The mean pre-pandemic pneumonia death rates were highly associated with pneumonia death rates during the pandemic period (Spearman ρ = 0.64–0.72; P<0.001). By contrast, there was a weak correlation between pre-pandemic and pandemic influenza mortality rates. Pneumonia mortality rates partially explained influenza mortality rates in 1918 (ρ = 0.34, P = 0.005) but not during any other year. Pneumonia death counts followed a linear relationship with population size in all study years, suggesting that pneumonia death rates were homogeneous across the range of population sizes studied. By contrast, influenza death counts followed a power law relationship with a scaling exponent of ∼0.81 (95%CI: 0.71, 0.91) in 1918, suggesting that smaller cities experienced worst outcomes during the pandemic. A linear relationship was observed for all other years. Our study suggests that mortality associated with the 1918–20 influenza pandemic was in part predetermined by pre-pandemic pneumonia death rates in 66 large US cities, perhaps through the impact of the physical and social structure of each city. Smaller cities suffered a disproportionately high per capita influenza mortality burden than larger ones in 1918, while city size did not affect pneumonia mortality rates in the pre-pandemic and pandemic periods. PMID:21886792

  9. "Betwixt Brewings": A History of College Students and Alcohol, 1820-1933

    ERIC Educational Resources Information Center

    Hevel, Michael Stephen

    2011-01-01

    This dissertation offers a history of white college students' relationship with alcohol between 1820 and 1933. The years that frame this study represent a long crisis regarding alcohol in the United States. A dramatic rise in alcohol consumption began around 1800, the negative consequences of which led growing numbers of Americans, for the first…

  10. Deciphering the Swine-Flu Pandemics of 1918 and 2009

    NASA Astrophysics Data System (ADS)

    Goldstein, Richard; Dos Reis, Mario; Tamuri, Asif; Hay, Alan

    The devastating "Spanish flu" of 1918 killed an estimated 50 million people worldwide, ranking it as the deadliest pandemic in recorded human history. It is generally believed that the virus transferred from birds directly to humans shortly before the start of the pandemic, subsequently jumping from humans to swine. By developing 'non-homogeneous' substitution models that consider that substitution patterns may be different in human, avian, and swine hosts, we can determine the timing of the host shift to mammals. We find it likely that the Spanish flu of 1918, like the current 2009 pandemic, was a 'swine-origin' influenza virus. Now that we are faced with a new pandemic, can we understand how influenza is able to change hosts? Again by modelling the evolutionary process, considering the different selective constraints for viruses in the different hosts, we can identify locations that seem to be under different selective constraints in humans and avian hosts. This allows us to identify changes that may have facilitated the establishment of the 2009 swine-origin flu in humans.

  11. 17 CFR 239.39 - Form F-9, for registration under the Securities Act of 1933 of certain investment grade debt or...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under the Securities Act of 1933 of certain investment grade debt or investment grade preferred... Statements § 239.39 Form F-9, for registration under the Securities Act of 1933 of certain investment grade debt or investment grade preferred securities of certain Canadian issuers. (a) Form F-9 may be used for...

  12. Not a slippery slope or sudden subversion: German medicine and national socialism in 1933.

    PubMed Central

    Hanauske-Abel, H. M.

    1996-01-01

    The history of medicine this century is darkened by the downfall of the German medical profession, exposed during the doctors' trial at Nuremberg in 1946. Relying largely on documents published during 1933 in German medical journals, this paper examines two widely accepted notions of those events, metaphorically termed "slippery slope" and "sudden subversion." The first connotes a gradual slide over infinitesimal steps until, suddenly, all footing is lost; the second conveys forced take over of the profession's leadership and values. Both concepts imply that the medical profession itself became the victim of circumstances. The slippery slope concept is a prominent figure of argument in the current debate on bioethics. The evidence presented here, however, strongly suggests that the German medical community set its own course in 1933. In some respects this course even outpaced the new government, which had to rein in the profession's eager pursuit of enforced eugenic sterilizations. In 1933 the convergence of political, scientific, and economic forces dramatically changed the relationship between the medical community and the government. That same convergence is occurring again and must be approached with great caution if medicine is to remain focused on the preservation of physical and medical integrity. Images p1456-a p1457-a p1457-b p1458-a p1459-a p1459-b Fig 1 PMID:8973235

  13. Dr. Goddard and a 1918 version of 'Bazooka'

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. Robert H. Goddard loading a 1918 version of the Bazooka of World War II. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets, which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

  14. Submarine landslide as the source for the October 11, 1918 Mona Passage tsunami: Observations and modeling

    USGS Publications Warehouse

    López-Venegas, A.M.; ten Brink, Uri S.; Geist, Eric L.

    2008-01-01

    The October 11, 1918 ML 7.5 earthquake in the Mona Passage between Hispaniola and Puerto Rico generated a local tsunami that claimed approximately 100 lives along the western coast of Puerto Rico. The area affected by this tsunami is now significantly more populated. Newly acquired high-resolution bathymetry and seismic reflection lines in the Mona Passage show a fresh submarine landslide 15 km northwest of Rinćon in northwestern Puerto Rico and in the vicinity of the first published earthquake epicenter. The landslide area is approximately 76 km2 and probably displaced a total volume of 10 km3. The landslide's headscarp is at a water depth of 1200 m, with the debris flow extending to a water depth of 4200 m. Submarine telegraph cables were reported cut by a landslide in this area following the earthquake, further suggesting that the landslide was the result of the October 11, 1918 earthquake. On the other hand, the location of the previously suggested source of the 1918 tsunami, a normal fault along the east wall of Mona Rift, does not show recent seafloor rupture. Using the extended, weakly non-linear hydrodynamic equations implemented in the program COULWAVE, we modeled the tsunami as generated by a landslide with a duration of 325 s (corresponding to an average speed of ~ 27 m/s) and with the observed dimensions and location. Calculated marigrams show a leading depression wave followed by a maximum positive amplitude in agreement with the reported polarity, relative amplitudes, and arrival times. Our results suggest this newly-identified landslide, which was likely triggered by the 1918 earthquake, was the primary cause of the October 11, 1918 tsunami and not the earthquake itself. Results from this study should be useful to help discern poorly constrained tsunami sources in other case studies.

  15. 392. J.R.L., Delineator August 1933 STATE OF CALIFORNIA; DEPARTMENT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    392. J.R.L., Delineator August 1933 STATE OF CALIFORNIA; DEPARTMENT OF PUBLIC WORKS; SAN FRANCISCO - OAKLAND BAY BRIDGE; SUPERSTRUCTURE - EAST BAY CROSSING; PIER El; ANCHORAGE STEEL WORK; CONTRACT NO. 7; SUP. DRAWING NO. 72A - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  16. The influenza virus neuraminidase protein transmembrane and head domains have coevolved.

    PubMed

    da Silva, Diogo V; Nordholm, Johan; Dou, Dan; Wang, Hao; Rossman, Jeremy S; Daniels, Robert

    2015-01-15

    Transmembrane domains (TMDs) from single-spanning membrane proteins are commonly viewed as membrane anchors for functional domains. Influenza virus neuraminidase (NA) exemplifies this concept, as it retains enzymatic function upon proteolytic release from the membrane. However, the subtype 1 NA TMDs have become increasingly more polar in human strains since 1918, which suggests that selection pressure exists on this domain. Here, we investigated the N1 TMD-head domain relationship by exchanging a prototypical "old" TMD (1933) with a "recent" (2009), more polar TMD and an engineered hydrophobic TMD. Each exchange altered the TMD association, decreased the NA folding efficiency, and significantly reduced viral budding and replication at 37°C compared to at 33°C, at which NA folds more efficiently. Passaging the chimera viruses at 37°C restored the NA folding efficiency, viral budding, and infectivity by selecting for NA TMD mutations that correspond with their polar or hydrophobic assembly properties. These results demonstrate that single-spanning membrane protein TMDs can influence distal domain folding, as well as membrane-related processes, and suggest the NA TMD in H1N1 viruses has become more polar to maintain compatibility with the evolving enzymatic head domain. The neuraminidase (NA) protein from influenza A viruses (IAVs) functions to promote viral release and is one of the major surface antigens. The receptor-destroying activity in NA resides in the distal head domain that is linked to the viral membrane by an N-terminal hydrophobic transmembrane domain (TMD). Over the last century, the subtype 1 NA TMDs (N1) in human H1N1 viruses have become increasingly more polar, and the head domains have changed to alter their antigenicity. Here, we provide the first evidence that an "old" N1 head domain from 1933 is incompatible with a "recent" (2009), more polar N1 TMD sequence and that, during viral replication, the head domain drives the selection of TMD

  17. Nonpharmaceutical Influenza Mitigation Strategies, US Communities, 1918–1920 Pandemic1

    PubMed Central

    Stern, Alexandra M.; Navarro, J. Alexander; Michalsen, Joseph R.; Monto, Arnold S.; DiGiovanni, Cleto

    2006-01-01

    We studied nonpharmaceutical interventions used to mitigate the second, and most deadly, wave of the 1918–1920 influenza pandemic in the United States. We conclude that several small communities implemented potentially successful attempts at preventing the introduction of influenza. PMID:17326953

  18. 367. J.W.G., Delineator August 1933 STATE OF CALIFORNIA; DEPARTMENT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    367. J.W.G., Delineator August 1933 STATE OF CALIFORNIA; DEPARTMENT OF PUBLIC WORKS; SAN FRANCISCO - OAKLAND BAY BRIDGE; SUPERSTRUCTURE - WEST BAY CROSSING; PIER NO. 5; GENERAL PLAN & ELEVATION; CONTRACT NO. 2; SUP. DRAWING NO. 10A - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  19. Epidemiological isolation causing variable mortality in Island populations during the 1918–1920 influenza pandemic

    PubMed Central

    Shanks, G. Dennis; Hussell, Tracy; Brundage, John F.

    2012-01-01

    Please cite this paper as: Shanks et al. (2012) Epidemiological isolation causing variable mortality in Island populations during the 1918–1920 influenza pandemic. Influenza and Other Respiratory Viruses 6(6), 417–423. Background  During the 1918 pandemic period, influenza‐related mortality increased worldwide; however, mortality rates varied widely across locations and demographic subgroups. Islands are isolated epidemiological situations that may elucidate why influenza pandemic mortality rates were so variable in apparently similar populations. Objectives  Our objectives were to determine and compare the patterns of pandemic influenza mortality on islands. Methods  We reviewed historical records of mortality associated with the 1918–1920 influenza pandemic in various military and civilian groups on islands. Results and Conclusions  Mortality differed more than 50‐fold during pandemic‐related epidemics on Pacific islands [range: 0·4% (Hawaii) to 22% (Samoa)], and on some islands, mortality sharply varied among demographic subgroups of island residents such as Saipan: Chamorros [12%] and Caroline Islanders [0·4%]. Among soldiers from island populations who had completed initial military training, influenza‐related mortality rates were generally low, for example, Puerto Rico (0·7%) and French Polynesia (0·13%). The findings suggest that among island residents, those who had been exposed to multiple, antigenically diverse respiratory pathogens prior to infection with the 1918 pandemic strain (e.g., less isolated) experienced lower mortality. The continuous circulation of antigenically diverse influenza viruses and other respiratory infectious agents makes widespread high mortality during future influenza pandemics unlikely. PMID:22226378

  20. "The Advance Guard of a New Motion Picture Art": Experimental Cinema, 1930-1933.

    ERIC Educational Resources Information Center

    Brandon, Thomas

    1978-01-01

    Ninety-eight articles from the five issues of "Experimental Cinema" are annotated. The magazine appeared from 1930 to 1933 and is credited with stimulating the emergence of world cinema culture in the United States, while demonstrating perceptions of working class interests and even revolutionary projections. (JMF)

  1. Setting the Stage for "Animal House": Student Drinking in College Novels, 1865-1933

    ERIC Educational Resources Information Center

    Hevel, Michael S.

    2014-01-01

    Depictions of college students' alcohol use changed substantially in novels published between 1865 and 1933, years in which higher education expanded and college students became the focus of popular culture. In novels published before 1920, student drinking oscillated widely, primarily mediated by gender, socioeconomic status, and…

  2. 29 CFR 1918.98 - Qualifications of machinery operators and supervisory training.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Qualifications of machinery operators and supervisory... General Working Conditions. § 1918.98 Qualifications of machinery operators and supervisory training. (a) Qualification of machinery operators. (1) Only an employee determined by the employer to be competent by reason...

  3. 29 CFR 1918.98 - Qualifications of machinery operators and supervisory training.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Qualifications of machinery operators and supervisory... General Working Conditions. § 1918.98 Qualifications of machinery operators and supervisory training. (a) Qualification of machinery operators. (1) Only an employee determined by the employer to be competent by reason...

  4. 29 CFR 1918.98 - Qualifications of machinery operators and supervisory training.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Qualifications of machinery operators and supervisory... General Working Conditions. § 1918.98 Qualifications of machinery operators and supervisory training. (a) Qualification of machinery operators. (1) Only an employee determined by the employer to be competent by reason...

  5. 29 CFR 1918.98 - Qualifications of machinery operators and supervisory training.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Qualifications of machinery operators and supervisory... General Working Conditions. § 1918.98 Qualifications of machinery operators and supervisory training. (a) Qualification of machinery operators. (1) Only an employee determined by the employer to be competent by reason...

  6. Literary Aspects of a Girlie Magazine: The Literary Contributions of Esquire, 1933-43.

    ERIC Educational Resources Information Center

    Peterson, Thane

    From its inauspicious beginnings as a men's store giveaway and a "girlie" magazine in 1933, "Esquire" magazine quickly established a policy of literary excellence. By 1945, the magazine included the works on such major literary figures as Erskine Caldwell, John Dos Passos, Dashiell Hammett, Ernest Hemingway, Ring Lardner, James…

  7. 7. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED 1918, HORIZONAL ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    7. PHOTOGRAPHIC COPY OF ORIGINAL CONSTRUCTION DRAWING, DATED 1918, HORIZONAL SLIDING WINDOW DETAIL, WAR DEPARTMENT, MANUAL OF THE CONSTRUCTION DIVISION OF THE ARMY, WAR EMERGENCY CONSTRUCTION, SECTION C, ENGINEERING DIVISION, PLATE 5, CONSOLIDATED SUPPLY COMPANY PRINTERS, WASHINGTON - Fort Bliss, 7th Cavalry Buildings, U.S. Army Air Defence Artillery Center & Fort Bliss, El Paso, El Paso County, TX

  8. Seismicity in the source areas of the 1896 and 1933 Sanriku earthquakes and implications for large near-trench earthquake faults

    NASA Astrophysics Data System (ADS)

    Obana, Koichiro; Nakamura, Yasuyuki; Fujie, Gou; Kodaira, Shuichi; Kaiho, Yuka; Yamamoto, Yojiro; Miura, Seiichi

    2018-03-01

    In the northern part of the Japan Trench, the 1933 Showa-Sanriku earthquake (Mw 8.4), an outer-trench, normal-faulting earthquake, occurred 37 yr after the 1896 Meiji-Sanriku tsunami earthquake (Mw 8.0), a shallow, near-trench, plate-interface rupture. Tsunamis generated by both earthquakes caused severe damage along the Sanriku coast. Precise locations of earthquakes in the source areas of the 1896 and 1933 earthquakes have not previously been obtained because they occurred at considerable distances from the coast in deep water beyond the maximum operational depth of conventional ocean bottom seismographs (OBSs). In 2015, we incorporated OBSs designed for operation in deep water (ultradeep OBSs) in an OBS array during two months of seismic observations in the source areas of the 1896 and 1933 Sanriku earthquakes to investigate the relationship of seismicity there to outer-rise normal-faulting earthquakes and near-trench tsunami earthquakes. Our analysis showed that seismicity during our observation period occurred along three roughly linear trench-parallel trends in the outer-trench region. Seismic activity along these trends likely corresponds to aftershocks of the 1933 Showa-Sanriku earthquake and the Mw 7.4 normal-faulting earthquake that occurred 40 min after the 2011 Tohoku-Oki earthquake. Furthermore, changes of the clarity of reflections from the oceanic Moho on seismic reflection profiles and low-velocity anomalies within the oceanic mantle were observed near the linear trends of the seismicity. The focal mechanisms we determined indicate that an extensional stress regime extends to about 40 km depth, below which the stress regime is compressional. These observations suggest that rupture during the 1933 Showa-Sanriku earthquake did not extend to the base of the oceanic lithosphere and that compound rupture of multiple or segmented faults is a more plausible explanation for that earthquake. The source area of the 1896 Meiji-Sanriku tsunami earthquake is

  9. Main lines of scientific and technical research at the Soviet Jet Propulsion Research Institute (RNII), 1933 - 1942

    NASA Technical Reports Server (NTRS)

    Shchetinkov, Y. S.

    1977-01-01

    The rapid development of rocketry in the U.S.S.R. during the post-war years was due largely to pre-war activity; in particular, to investigations conducted in the Jet Propulsion Research Institute (RNII). The history of RNII commenced in 1933, resulting from the merger of two rocket research organizations. Previous research was continued in areas of solid-propellant rockets, jet-assisted take-off of aircraft, liquid propellant engines (generally with nitric acid as the oxidizer), liquid-propellant rockets (generally with oxgen as the oxidizer), ram jet engines, rockets with and without wings, and rocket planes. RNII research is described and summarized for the years 1933-1942.

  10. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 15 Commerce and Foreign Trade 1 2014-01-01 2014-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  11. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 15 Commerce and Foreign Trade 1 2013-01-01 2013-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  12. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 15 Commerce and Foreign Trade 1 2011-01-01 2011-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  13. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 15 Commerce and Foreign Trade 1 2012-01-01 2012-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  14. 15 CFR 19.18 - How does a debtor request a special review based on a change in circumstances such as...

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false How does a debtor request a special....18 Section 19.18 Commerce and Foreign Trade Office of the Secretary of Commerce COMMERCE DEBT COLLECTION Procedures To Collect Commerce Debts § 19.18 How does a debtor request a special review based on a...

  15. 32 CFR 191.8 - Defense equal opportunity council and EEO boards.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... development in the Department of Defense. The Boards shall work with career management officials, other key... 32 National Defense 2 2010-07-01 2010-07-01 false Defense equal opportunity council and EEO boards... DEFENSE (CONTINUED) MISCELLANEOUS THE DOD CIVILIAN EQUAL EMPLOYMENT OPPORTUNITY (EEO) PROGRAM § 191.8...

  16. The Rise of Totalitarianism and Its Influence on Educators and Intellectuals in Prewar Japan

    DTIC Science & Technology

    2013-09-10

    governmental manipulations at the Kyoto Imperial University in 1933, the year Japan seceded from the League of Nations. Japanese imperialistic fascism...Ichiro, The Emperor Organ Theory, Kyoto Imperial University , Fascism, Kokutai, The Communist Party, The Freedom and Civil Rights Movement, Minoda...already had begun to be reflected in Article 1 of the 1918 University Ordinance.2 An article entitled "Chishikijin no kokka ishiki" (The View of the

  17. Regional patterns of mortality during the 1918 influenza pandemic in Newfoundland.

    PubMed

    Sattenspiel, Lisa

    2011-07-22

    The Spanish Influenza pandemic reached the island of Newfoundland in the summer of 1918 and by the time it disappeared, nearly 2000 of its 250,000 residents died. The pandemic spread in several waves, including a mild outbreak during the summer of 1918 (Wave I), a major, deadly outbreak in the succeeding fall and spring (Wave II), and a small echo wave in 1920. All parts of the island experienced the epidemic, but the effects varied across districts, both in timing and in severity. Overall P&I mortality rates across districts during the entire epidemic (1918-1920) ranged from 28.6 to 109.3 deaths per 10,000 population, with the island as a whole experiencing a mortality rate of 74.5 per 10,000. This island-wide mortality rate was 4.5 times higher than the P&I mortality rate for the 3 years immediately preceding the epidemic. Estimates of the reproduction number, R, range from 1.2 to 2.4 for Wave I and from 2.4 to 9.3 for Wave II. The pandemic experience on Newfoundland illustrates the high degree of regional variability in incidence and severity that epidemics can exhibit. In addition, compared to other world regions, the island's pandemic peaked relatively late and exhibited an unusual bimodal peak during Wave II, emphasizing that local and regional conditions can have major influences on timing, location, and rate of spread. This suggests the need to for greater understanding of how local factors influence epidemic spread so that more effective control strategies can be developed for populations experiencing future influenza pandemics. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. The October 11, 1918 Mona Passage tsunami modeled using new submarine landslide evidence.

    NASA Astrophysics Data System (ADS)

    López, A. M.; ten Brink, U.; Geist, E.

    2007-12-01

    The October 11, 1918 ML 7.5 earthquake in the Mona Passage betweeen Hispaniola and Puerto Rico generated a local tsunami that claimed approximately 100 lives along the western coast of Puerto Rico. The area affected by this tsunami is now many-fold more populated. Although the exact cause of the tsunami is still unclear, newly-acquired high-resolution bathymetry of the Mona Passage and seismic reflection lines show a fresh submarine landslide 12 km northwest of Rincón in northwestern Puerto Rico and in the vicinity of the earthquake epicenter determined by Doser et al., (2005). The landslide area is approximately 76 km2 and probably displaced a total volume of 10 km3. The landslide's head scarp is at a water depth of 1.2 km, with the debris flow extending down to a water depth of 4.5 km. The seismic profiles and multibeam bathymetry indicate that the previously suggested source of the 1918 tsunami, a normal fault along the east side of Mona Rift (Mercado and McCann, 1998), was not active recently. The fault escarpment along Desecheo Ridge, which is near the Doser et al., (2005) epicenter, and our landslide appear, on the other hand, to be rather fresh. Using the extended, weakly non-linear hydrodynamic equations implemented in the program COULWAVE (Lynett and Liu, 2002), we modeled the tsunami by a landslide with a finite duration and with the observed dimensions and location. Marigrams (time series of sea level) were calculated at locations near to reported locations of runup. The marigrams show a leading depression wave followed by a maximum positive amplitude in good agreement with the reported polarity, relative amplitudes, and arrival times. Our results suggest this newly-identified landslide, which was likely triggered by the 1918 earthquake, was the probable cause of the October 11, 1918 tsunami and not a normal fault rupture as previously suggested.

  19. Epidemiological isolation causing variable mortality in Island populations during the 1918-1920 influenza pandemic.

    PubMed

    Shanks, G Dennis; Hussell, Tracy; Brundage, John F

    2012-11-01

    During the 1918 pandemic period, influenza-related mortality increased worldwide; however, mortality rates varied widely across locations and demographic subgroups. Islands are isolated epidemiological situations that may elucidate why influenza pandemic mortality rates were so variable in apparently similar populations. Our objectives were to determine and compare the patterns of pandemic influenza mortality on islands. We reviewed historical records of mortality associated with the 1918-1920 influenza pandemic in various military and civilian groups on islands. Mortality differed more than 50-fold during pandemic-related epidemics on Pacific islands [range: 0.4% (Hawaii) to 22% (Samoa)], and on some islands, mortality sharply varied among demographic subgroups of island residents such as Saipan: Chamorros [12%] and Caroline Islanders [0.4%]. Among soldiers from island populations who had completed initial military training, influenza-related mortality rates were generally low, for example, Puerto Rico (0.7%) and French Polynesia (0.13%). The findings suggest that among island residents, those who had been exposed to multiple, antigenically diverse respiratory pathogens prior to infection with the 1918 pandemic strain (e.g., less isolated) experienced lower mortality. The continuous circulation of antigenically diverse influenza viruses and other respiratory infectious agents makes widespread high mortality during future influenza pandemics unlikely. © 2012 Blackwell Publishing Ltd.

  20. Mortality patterns associated with the 1918 influenza pandemic in Mexico: evidence for a spring herald wave and lack of pre-existing immunity in older populations

    PubMed Central

    Chowell, Gerardo; Viboud, Cécile; Simonsen, Lone; Miller, Mark A.; Acuna-Soto, Rodolfo

    2010-01-01

    Background While the mortality burden of the devastating 1918 influenza pandemic has been carefully quantified in the US, Japan, and European countries, little is known about the pandemic experience elsewhere. Here, we compiled extensive archival records to quantify the pandemic mortality patterns in two Mexican cities, Mexico City and Toluca. Methods We applied seasonal excess mortality models to age-specific respiratory mortality rates for 1915–1920 and quantified the reproduction number from daily data. Results We identified 3 pandemic waves in Mexico City in spring 1918, fall 1918, and winter 1920, characterized by unusual excess mortality in 25–44 years old. Toluca experienced 2-fold higher excess mortality rates than Mexico City, but did not have a substantial 3rd wave. All age groups including those over 65 years experienced excess mortality during 1918–20. Reproduction number estimates were below 2.5 assuming a 3-day generation interval. Conclusion Mexico experienced a herald pandemic wave with elevated young adult mortality in spring 1918, similar to the US and Europe. In contrast to the US and Europe, there was no mortality sparing in Mexican seniors, highlighting potential geographical differences in pre-existing immunity to the 1918 virus. We discuss the relevance of our findings to the 2009 pandemic mortality patterns. PMID:20594109

  1. White-Nose Syndrome Fungus in a 1918 Bat Specimen from France.

    PubMed

    Campana, Michael G; Kurata, Naoko P; Foster, Jeffrey T; Helgen, Lauren E; Reeder, DeeAnn M; Fleischer, Robert C; Helgen, Kristofer M

    2017-09-01

    White-nose syndrome, first diagnosed in North America in 2006, causes mass deaths among bats in North America. We found the causative fungus, Pseudogymnoascus destructans, in a 1918 sample collected in Europe, where bats have now adapted to the fungus. These results are consistent with a Eurasian origin of the pathogen.

  2. 378. A.C.S., Delineator March 1933 STATE OF CALIFORNIA; DEPARTMENT OF ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    378. A.C.S., Delineator March 1933 STATE OF CALIFORNIA; DEPARTMENT OF PUBLIC WORKS; SAN FRANCISCO - OAKLAND BAY BRIDGE; CONTRACT NO. 6A; SUPERSTRUCTURE - WEST BAY CROSSING; YERBA BUENA ANCHORAGE & CABLE BENT. AMERICAN BRIDGE CO.; AMBRIDGE PLANT; ORDER NO. G 4866; SHEET NO. E4 - San Francisco Oakland Bay Bridge, Spanning San Francisco Bay, San Francisco, San Francisco County, CA

  3. Eduard Spranger's Opposition to Higher-Educational Policy in 1933--A Prussian Scholar's Political Action.

    ERIC Educational Resources Information Center

    Tenorth, Heinz-Elmar

    1990-01-01

    Discusses Eduard Spranger's 1933 resignation from the University of Berlin from the internal perspectives of the Ministry of Culture and Spranger himself. Examines how his resignation influenced his subsequent philosophical reflections. Argues Spranger's conflict with university policy resulted in both his political distance from Nazism and a…

  4. 29 CFR 1918.66 - Cranes and derricks other than vessel's gear.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... body of the crane and any fixed structure or between parts of the crane. (3) Prohibited usage. (i....g., a computer) providing indications in the cab according to the radius and load at the moment; or... survey (see § 1918.11) and at such additional times as may be recommended by the manufacturer. (iv) When...

  5. 29 CFR 1918.66 - Cranes and derricks other than vessel's gear.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... body of the crane and any fixed structure or between parts of the crane. (3) Prohibited usage. (i....g., a computer) providing indications in the cab according to the radius and load at the moment; or... survey (see § 1918.11) and at such additional times as may be recommended by the manufacturer. (iv) When...

  6. 29 CFR 1918.66 - Cranes and derricks other than vessel's gear.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... body of the crane and any fixed structure or between parts of the crane. (3) Prohibited usage. (i....g., a computer) providing indications in the cab according to the radius and load at the moment; or... survey (see § 1918.11) and at such additional times as may be recommended by the manufacturer. (iv) When...

  7. 29 CFR 1918.66 - Cranes and derricks other than vessel's gear.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... body of the crane and any fixed structure or between parts of the crane. (3) Prohibited usage. (i....g., a computer) providing indications in the cab according to the radius and load at the moment; or... survey (see § 1918.11) and at such additional times as may be recommended by the manufacturer. (iv) When...

  8. 29 CFR 1918.66 - Cranes and derricks other than vessel's gear.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... body of the crane and any fixed structure or between parts of the crane. (3) Prohibited usage. (i....g., a computer) providing indications in the cab according to the radius and load at the moment; or... survey (see § 1918.11) and at such additional times as may be recommended by the manufacturer. (iv) When...

  9. 37 CFR 1.933 - Patent owner duty of disclosure in inter partes reexamination proceedings.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE GENERAL RULES OF PRACTICE IN PATENT CASES Inter Partes Reexamination of Patents That Issued From an Original Application Filed in the United States on or After November 29, 1999 Information Disclosure in Inter Partes Reexamination § 1.933 Patent...

  10. Americanization as a War Measure: Report of a Conference Called by the Secretary of the Interior, and Held in Washington, April 3, 1918. Bulletin, 1918, No. 18

    ERIC Educational Resources Information Center

    Bureau of Education, Department of the Interior, 1918

    1918-01-01

    At the suggestion of the National Committee of One Hundred, the Advisory Council on Americanization to the United States Bureau of Education, the Secretary of the Interior called a conference on Americanization as a War Measure, which was held on April 3, 1918. Among those in attendance were governors, State officers, officials of commercial and…

  11. The Coast Artillery Journal. Volume 76, Number 2, March-April 1933

    DTIC Science & Technology

    1933-04-01

    two bundles of bamboo poles (20 each) lashed to sides of wheels at the hub . Left: Escort wagon floated by means of its own wav;on cover. load is also...attrac- tive advertising space Congress legislated advertising out of the picture and the reduced income forced the JOURNAL to a bimonthly schedule of...8217allSwere forced tD use French guns for the duration of the war for mobilebatteries. The three-inch, trailer mount, model 1918, never saw ac- tion. All

  12. [Max Eitingon in Palestine/Eretz Israel (1933-1943)].

    PubMed

    Liebermann, Guido

    2015-01-01

    In 1933, after the Nazi takeover in Germany, Eitingon decided to settle in Palestine. His ten Jerusalem years highlight a multifaceted personality that does not quite correspond to his usual image as a "grey eminence" of the international psychoanalytic movement: enthusiastic, vivid, highly involved in various--artistic, scientific, academic, social and pedagogic--acitivities of zionism in Palestine. In contrast, his last years were overshadowed by illness, financial ruin und the tragedies of war. Eitingon played a major role in the establishment of psychoanalysis in Palestine. However, the omnipresence of his name, associated with a purely Berlin psychoanalytic tradition, tends to obscure the important contributions of representatives of the Viennese tradition and the significant achievement of Moshe Wulff who was the real pioneer of psychoanalysis in Israel.

  13. The Coast Artillery Journal. Volume 76, Number 4, July-August 1933

    DTIC Science & Technology

    1933-08-01

    work camps extending from the Atl,antic to the Pacific and from the Canadian bor- der to the Gulf ,of Mexico . It,represented the greatest peace-time...distributed in depth from Canada to Mexico , occupying every state or the Union excepting only Delaware, and move 55,000 of them a distance of 2200...8217thOl’ough physical examination. followed by an innoculation for .July-Aug., 1933 Let the Army Do It! ~69 typhoid and para-typhoid and a small- pox

  14. [Madness in the German cinema (1913-1933].

    PubMed

    Aulas, J J

    1980-01-01

    During these twenty years, from 1913 to 1933, of the history of the German cinema, the cinematographic representation of madness varies according to the fluctuations of the social and economical background. The political and ideological chaos of the immediate post-war years was symbolized in the allegorical imagery of unreason in the expressionist cinema. The same equivalence, the same symbolization can be found in the cinema of the thirties when the crash of Wall-Street foretells a crisis like the former. On the contrary in the course of the so-called "relative stabilization" (1924-1929) the meaning of the representation of madness is totally different from the representation of the previous period. At this period of economical restoration, madness which could henceforth be cured on the psychoanalyst's couch (acc. G. W. Pabst's film: "Geheimnisse einer Seele") became the symbol of the absolute power rediscovered by Germany.

  15. Photographic copy of October 20, 1933, black and white studio ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of October 20, 1933, black and white studio panoramic view. Located in folder 3 of 3 in box 15 of 94 at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C., Charles L. Frank, Photographer, The Billings Studio. STUDIO PANORAMIC VIEW PART TWO OF TWO OF ENTIRE BRIDGE PIERS UNDER CONSTRUCTION LOOKING DOWN STREAM FROM EAST BANK ON LEFT TOWARD WEST BANK ON RIGHT. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  16. Photographic copy of October 20, 1933, black and white studio ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of October 20, 1933, black and white studio panoramic view. Located in folder 3 of 3 in box 15 of 94 at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C., Charles L. Frank, Photographer, The Billings Studio. OCTOBER 20, STUDIO PANORAMIC VIEW PART ONE OF TWO OF ENTIRE BRIDGE PIERS UNDER CONSTRUCTION LOOKING DOWN STREAM FROM EAST BANK ON LEFT TOWARD WEST BANK ON RIGHT. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  17. Educational Work of the Churches in 1916-1918. Bulletin, 1919, No. 10

    ERIC Educational Resources Information Center

    Bureau of Education, Department of the Interior, 1919

    1919-01-01

    This bulletin discusses educational work of the churches in 1916-1918. Contents include: (1) Education under Religious Auspices (B. Warren Brown); (2) Christian Day Schools of the Lutheran Church (W. C. Kohn); (3) Education in the Methodist Episcopal Church (Henry H. Meyer); (4) Educational Work of the Methodist Episcopal Church, South (W. E.…

  18. The Michael-Adler report (1933): criminology under the microscope.

    PubMed

    Goff, Colin; Geis, Gilbert

    2008-01-01

    This paper details the responses made by social scientists as well as criminal justice practitioners during 1932 to a study focusing on the status of criminology by the Bureau of Social Hygiene. These responses ultimately led to the publication of the controversial Crime, Law and Social Science (1933), which gave much-needed direction to the development of criminology. Despite the importance of these responses to the creation of criminological thought, only one (by Edwin H. Sutherland) has previously been published. Examining the responses of all of the individual participants in the project gives a clearer picture of controversies and changes which ultimately occurred as the field of criminology gradually became institutionalized as an academic discipline.

  19. Photocopy of panoramic photograph entitled "Ground Breaking, April 27, 1918, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photocopy of panoramic photograph entitled "Ground Breaking, April 27, 1918, U.S.A. General Hospital no. 21…". Photograph by Rocky Mountain photo and is in the Fitzsimons Army Medical Center Public Affairs Office, building 120. Photograph in public domain as it is not copyrighted. - Fitzsimons General Hospital, Bounded by East Colfax to south, Peoria Street to west, Denver City/County & Adams County Line to north, & U.S. Route 255 to east, Aurora, Adams County, CO

  20. The great 1933 Sanriku-oki earthquake: reappraisal of the main shock and its aftershocks and implications for its tsunami using regional tsunami and seismic data

    NASA Astrophysics Data System (ADS)

    Uchida, Naoki; Kirby, Stephen H.; Umino, Norihito; Hino, Ryota; Kazakami, Tomoe

    2016-09-01

    The aftershock distribution of the 1933 Sanriku-oki outer trench earthquake is estimated by using modern relocation methods and a newly developed velocity structure to examine the spatial extent of the source-fault and the possibility of a triggered interplate seismicity. In this study, we first examined the regional data quality of the 1933 earthquake based on smoked-paper records and then relocated the earthquakes by using the 3-D velocity structure and double-difference method. The improvements of hypocentre locations using these methods were confirmed by the examination of recent earthquakes that are accurately located based on ocean bottom seismometer data. The results show that the 1933 aftershocks occurred under both the outer- and inner-trench-slope regions. In the outer-trench-slope region, aftershocks are distributed in a ˜280-km-long area and their depths are shallower than 50 km. Although we could not constrain the fault geometry from the hypocentre distribution, the depth distribution suggests the whole lithosphere is probably not under deviatoric tension at the time of the 1933 earthquake. The occurrence of aftershocks under the inner trench slope was also confirmed by an investigation of waveform frequency difference between outer and inner trench earthquakes as recorded at Mizusawa. The earthquakes under the inner trench slope were shallow (depth ≦30 km) and the waveforms show a low-frequency character similar to the waveforms of recent, precisely located earthquakes in the same area. They are also located where recent activity of interplate thrust earthquakes is high. These suggest that the 1933 outer-trench-slope main shock triggered interplate earthquakes, which is an unusual case in the order of occurrence in contrast with the more common pairing of a large initial interplate shock with subsequent outer-slope earthquakes. The off-trench earthquakes are distributed about 80 km width in the trench perpendicular direction. This wide width cannot

  1. 19 CFR 19.18 - Smelting and refining; allowance for wastage; withdrawal for consumption.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 19 Customs Duties 1 2010-04-01 2010-04-01 false Smelting and refining; allowance for wastage... OF MERCHANDISE THEREIN Smelting and Refining Warehouses § 19.18 Smelting and refining; allowance for... liquidation of the entry for losses on copper, lead, and zinc content of metal-bearing materials, pursuant to...

  2. 19 CFR 19.18 - Smelting and refining; allowance for wastage; withdrawal for consumption.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 19 Customs Duties 1 2011-04-01 2011-04-01 false Smelting and refining; allowance for wastage... OF MERCHANDISE THEREIN Smelting and Refining Warehouses § 19.18 Smelting and refining; allowance for... liquidation of the entry for losses on copper, lead, and zinc content of metal-bearing materials, pursuant to...

  3. Photographic copy of circa 1933, 10” x 15” black and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of circa 1933, 10” x 15” black and white aerial photograph. Loose in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. Original Photographer unknown. AERIAL PHOTOGRAPH SHOWING CONSTRUCTION OF PIERS A, I, II, AND III BEGINNING ON EAST BANK OF RIVER. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  4. Photographic copy of circa 1933, 10” x 15” black and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of circa 1933, 10” x 15” black and white aerial photograph. Loose in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. Original Photographer unknown. AERIAL PHOTOGRAPH SHOWING CONSTRUCTION OF EAST BANK RAILROAD AND BRIDGE APPROACH AT JEFFERSON HIGHWAY INTERSECTION. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  5. Photographic copy of circa 1933, 10” x 15” black and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of circa 1933, 10” x 15” black and white aerial photograph. Loose in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. Original Photographer unknown. AERIAL PHOTOGRAPH SHOWING EAST BANK CONSTRUCTION OF PIER A AND I AND COMPLETED CONSTRUCTION TRESTLE. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  6. 76 FR 49698 - Covered Securities Pursuant to Section 18 of the Securities Act of 1933

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-08-11

    ... [Release No. 33-9251; File No. S7-31-11] RIN 3235-AL20 Covered Securities Pursuant to Section 18 of the... under Section 18 of the Securities Act of 1933 (``Securities Act''), as amended, to designate certain securities on BATS Exchange, Inc. (``BATS'' or ``Exchange'') as covered securities for purposes of Section 18...

  7. Lessons from the 1918 Influenza Pandemic: Using Historical Examples to Inform the Department of Defense’s Response to the Next Pandemic

    DTIC Science & Technology

    2013-04-01

    international containment as near as possible to the origin of an outbreak. Conclusion: The influenza pandemic of 1918 was the most rapidly lethal...fighting strength. Troop ships from the US delivered 1,700 new influenza cases to Brest , France in September 1918.26 These sick soldiers, far from...the population of the US during the pandemic because distrust and terror follow fear. 47 Fear led people to question the origin of the

  8. The Planetarium and the Carl Zeiss Corporation, 1923-1933

    NASA Astrophysics Data System (ADS)

    Boyce-Jacino, Katherine

    2018-01-01

    The Carl Zeiss Company of Jena, Germany, introduced the first prototype planetarium in the fall of 1923. By 1933, there were a dozen planetaria in Germany alone, and nearly a dozen more abroad. This talk argues that on one hand, Zeiss saw the planetarium as an opportunity to reintroduce German engineering to a skeptical international market. On the other, Zeiss recognized that a large part of the planetarium’s domestic appeal lay in the romance of its German origins. Through an examination of Zeiss’ corporate correspondence, propaganda, and contemporary international and domestic press, this talk argues that in advertising the planetarium in Germany and abroad, the Zeiss company relied on competing constructions of a post-war German identity rooted in conflicting understandings of space.

  9. Photographic copy of circa 1933, 10” x 15” black and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of circa 1933, 10” x 15” black and white aerial photograph. Loose in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. Original Photographer unknown. AERIAL PHOTOGRAPH SHOWING CONSTRUCTION OF PIER NO.’S V AND B LOOKING AT WEST BANK APPROACH UNDER CONSTRUCTION. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  10. Photographic copy of circa 1933, 10” x 15” black and ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    Photographic copy of circa 1933, 10” x 15” black and white aerial photograph. Loose in oversized box located at the National Museum of American History, Smithsonian Institution, Archives Center, Work and Industry Division, Washington, D.C. Original Photographer unknown. AERIAL PHOTOGRAPH SHOWING CONSTRUCTION OF PIER NO.’S III, 1V, V, AND B WITH WEST BANK APPROACH AT LOWER EDGE. - Huey P. Long Bridge, Spanning Mississippi River approximately midway between nine & twelve mile points upstream from & west of New Orleans, Jefferson, Jefferson Parish, LA

  11. William L. Donn 1918-1987

    NASA Astrophysics Data System (ADS)

    Gedzelman, Stanley David

    William L. Donn, Professor Emeritus of the Department of Earth and Planetary Sciences, City College of New York, and Special Research Scientist at Lamont-Doherty Geological Observatory (LDGO) of Columbia University (Palisades, N.Y.), died at his home on June 30, 1987, at the age of 69. Bill demonstrated expertise in a wide range of fields, with a highly productive and creative research and writing career that included geology, oceanography, climatology, atmospheric physics, and meteorology.Donn was born in Brooklyn, N.Y., on March 2, 1918. At the tender age of 10 years, he demonstrated his love and talent for science by building a telescope with his brother, Bertram. During his undergraduate years at Brooklyn College, he switched his major from astronomy to geology. He was largely selftrained in both meteorology and oceanography, serving as head of the Meteorology Section, U.S. Merchant Marine Academy during World War II . One by-product of these years was the textbook Meteorology—With Marine Applications, first published in 1946. This widely adopted text became a standard for a generation of mariners and college students.

  12. Solving the "Rural School Problem": New State Aid, Standards, and Supervision of Local Schools, 1900-1933

    ERIC Educational Resources Information Center

    Steffes, Tracy L.

    2008-01-01

    In 1918, Minnesota county superintendent Julius Arp argued that the greatest educational problem facing the American people was the Rural School Problem, saying: "There is no defect more glaring today than the inequality that exists between the educational facilities of the urban and rural communities. Rural education in the United States has…

  13. 29 CFR Appendix I to Part 1918 - Cargo Gear Register and Certificates (Non-mandatory)

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Appendix I to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH... recommended by the International Labour Office. This Register and related certificates shall be kept available... repair to any stress bearing part, and (b) in the case of lifting appliances, at least once in every five...

  14. 29 CFR Appendix I to Part 1918 - Cargo Gear Register and Certificates (Non-mandatory)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... Appendix I to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH... recommended by the International Labour Office. This Register and related certificates shall be kept available... repair to any stress bearing part, and (b) in the case of lifting appliances, at least once in every five...

  15. 29 CFR Appendix I to Part 1918 - Cargo Gear Register and Certificates (Non-mandatory)

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Appendix I to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH... recommended by the International Labour Office. This Register and related certificates shall be kept available... repair to any stress bearing part, and (b) in the case of lifting appliances, at least once in every five...

  16. 29 CFR Appendix I to Part 1918 - Cargo Gear Register and Certificates (Non-mandatory)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Appendix I to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH... recommended by the International Labour Office. This Register and related certificates shall be kept available... repair to any stress bearing part, and (b) in the case of lifting appliances, at least once in every five...

  17. 29 CFR Appendix I to Part 1918 - Cargo Gear Register and Certificates (Non-mandatory)

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Appendix I to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH... recommended by the International Labour Office. This Register and related certificates shall be kept available... repair to any stress bearing part, and (b) in the case of lifting appliances, at least once in every five...

  18. English Teaching and the Educationalisation of Social Problems in the United States, 1894-1918

    ERIC Educational Resources Information Center

    Brass, Jory

    2016-01-01

    This study draws from histories of "educationalisation" and neo-Foucaultian histories of English teaching in an archival analysis that revisits landmark pedagogical texts that coincided with the rapid expansion of the school subject English in between the 1894 Report of the Committee of Ten and 1918 Cardinal Principles of Secondary…

  19. [Mortality from respiratory diseases in the provinces of Apulia Region (Southern Italy) from 1933 to 2010].

    PubMed

    Montinari, Maria Rosa; Gianicolo, Emilio Antonio Luca; Vigotti, Maria Angela

    2016-01-01

    OBIETTIVI: valutare l'andamento temporale della mortalità per patologie respiratorie nelle province pugliesi utilizzando dati omogenei per fonte e metodologia di calcolo. DISEGNO: analisi ecologica storica degli andamenti temporali di mortalità per tumori e patologie dell'apparato respiratorio nelle province pugliesi, in Puglia e nelle ripartizioni geografiche italiane dal 1933 al 2010. SETTING E PARTECIPANTI: i dati di mortalità e le popolazioni residenti sono di fonte Istat. Sono state esaminate tutte le cause di decesso, il tumore della laringe, il tumore del polmone, l'insieme dei tumori respiratori, la bronchite, la polmonite e la broncopolmonite considerate congiuntamente, e l'insieme delle patologie respiratorie. Le analisi sono disaggregate per sesso dal 1969. PRINCIPALI MISURE DI OUTCOME: rapporti standardizzati di mortalità (SMR%) in riferimento all'Italia, con intervalli di confidenza al 95%, e tassi di mortalità standardizzati col metodo diretto (TSD ) in riferimento alla popolazione standard europea. RISULTATI: dal 1933 al 2010, i TSD per tumori respiratori e per bronchiti diminuiscono in tutte le aree analizzate. Tuttavia, nelle province di Taranto, Brindisi e Lecce, l'SMR% per tumori respiratori, inferiore al riferimento nazionale fino agli anni Sessanta, si allinea (a Brindisi) e supera (a Lecce e Taranto) il riferimento negli anni successivi. Nelle province di Foggia e Bari il numero dei decessi per tumore del polmone è costantemente inferiore all'atteso. CONCLUSIONI: la ricostruzione storica e l'analisi dei trend temporali di mortalità dal 1933 al 2010 mostrano alcune criticità sanitarie in periodi specifici. L'elaborazione dei dati di mortalità per un arco temporale di circa 80 anni ha messo in evidenza la maggiore rilevanza di queste criticità con l'avvio dello sviluppo industriale.

  20. 29 CFR 1918.96 - Maintenance and repair work in the vicinity of longshoring operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... General Working Conditions. § 1918.96 Maintenance and repair work in the vicinity of longshoring... 29 Labor 7 2010-07-01 2010-07-01 false Maintenance and repair work in the vicinity of longshoring... operations shall not be carried on in the hold or on deck beneath work being conducted overhead whenever such...

  1. 75 FR 48362 - Notice Pursuant to the National Cooperative Research and Production Act of 1933-PXI Systems...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-10

    ... DEPARTMENT OF JUSTICE Antitrust Division Notice Pursuant to the National Cooperative Research and Production Act of 1933-PXI Systems Alliance, Inc. Correction In notice document 2010-12033 appearing on page 28294 in the issue of Thursday, May 20, 2010 make the following correction: In the second column, in the...

  2. Exceptionally high mortality rate of the 1918 influenza pandemic in the Brazilian naval fleet

    PubMed Central

    Schuck‐Paim, Cynthia; Shanks, G. Dennis; Almeida, Francisco E. A.; Alonso, Wladimir J.

    2012-01-01

    Please cite this paper as: Schuck‐Paim et al. (2012) Exceptionally high mortality rate of the 1918 influenza pandemic in the Brazilian naval fleet. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750‐2659.2012.00341.x. Background  The naval experience with the 1918 pandemic during World War I remains underexplored despite its key role on the pandemic’s global diffusion and the epidemiological interest of isolated and relatively homogeneous populations. The pandemic outbreak in the Brazilian naval fleet is of particular interest both because of its severity and the fact that it was the only Latin American military force deployed to war. Objectives  To study the mortality patterns of the pandemic in the Brazilian fleet sent to patrol the West African coast in 1918. Method  We investigated mortality across vessels, ranks, and occupations based on official population and mortality records from the Brazilian Navy Archives. Results  The outbreak that swept this fleet included the highest influenza mortality rate on any naval ship reported to date. Nearly 10% of the crews died, with death rates reaching 13–14% on two destroyers. While overall mortality was lower for officers, stokers and engineer officers were significantly more likely to die from the pandemic, possibly due to the pulmonary damage from constant exposure to the smoke and coal dust from the boilers. Conclusions  The fatality patterns observed provide valuable data on the conditions that can exacerbate the impact of a pandemic. While the putative lack of exposure to a first pandemic wave may have played a role in the excessive mortality observed in this fleet, our results indicate that strenuous labor conditions, dehydration, and exposure to coal dust were major risk factors. The unequal death rates among vessels remain an open question. PMID:22336427

  3. Tadeusz Banachiewicz in Tartu (1915 to 1918)

    NASA Astrophysics Data System (ADS)

    Flin, P.; Panko, E.

    Tadeusz Banachiewicz (1882--1954) was an outstanding Polish astro\\-nomer, mathematician and geodesist. He was a professor at the Jagiellonian University in Cracow and director of the Astronomical Observatory (1919--1954), and had a strong influence on Polish astronomy. His achievements led to honorary degrees at universities, fellowships in academies of sciences, and the prestige of high positions in international organizations, such as the International Astronomical Union and the Baltic Geodetic Commission. He is known from both his theoretical and observational studies, his famous motto being: ``observo ergo sum''. Here we recall three years of his activity in Tartu, where Tadeusz Banachiewicz made the most important steps in his career. He arrived at Yuryev in October of 1915, employed as a young assistant. In March 1918 he became the extraordinary professor and director of the Astronomical Observatory.

  4. Risk factors for death from pandemic influenza in 1918–1919: a case–control study

    PubMed Central

    Summers, Jennifer A; Stanley, James; Baker, Michael G; Wilson, Nick

    2014-01-01

    Background Despite the persisting threat from future influenza pandemics, much is still unknown about the risk factors for death from such events, and especially for the 1918–1919 influenza pandemic. Methods A case–control study was performed to explore possible risk factors for death from pandemic influenza among New Zealand military personnel in the Northern Hemisphere in 1918–1919 (n = 218 cases, n = 221 controls). Data were compiled from a Roll-of-Honour dataset, a dataset of nearly all military personnel involved in the war and archived individual records. Results In the fully adjusted multivariable model, the following were significantly associated with increased risk of death from pandemic influenza: age (25–29 years), pre-pandemic hospitalisations for a chronic condition (e.g. tuberculosis), relatively early year of military deployment, a relatively short time from enlistment to foreign service, and having a larger chest size (e.g. adjusted odds ratio for 90–99 cm versus <90 cm was 2·45; 95% CI=1·47–4·10). There were no significant associations in the fully adjusted model with military rank, occupational class at enlistment, and rurality at enlistment. Conclusions This is one of the first published case–control studies of mortality risk factors for the 1918–1919 influenza pandemic. Some of the findings are consistent with previous research on risk factors (such as chronic conditions and age groups), but others appear more novel (e.g., larger chest size). As all such historical analyses have limitations, there is a need for additional studies in other settings as archival World War One records become digitalised. PMID:24490663

  5. Limits on the mass, velocity and orbit of PSR J1933-6211

    NASA Astrophysics Data System (ADS)

    Graikou, E.; Verbiest, J. P. W.; Osłowski, S.; Champion, D. J.; Tauris, T. M.; Jankowski, F.; Kramer, M.

    2017-11-01

    We present a high-precision timing analysis of PSR J1933-6211, a millisecond pulsar with a 3.5 ms spin period and a white dwarf (WD) companion, using data from the Parkes radio telescope. Since we have accurately measured the polarization properties of this pulsar, we have applied the matrix template matching approach in which the times of arrival are measured using full polarimetric information. We achieved a weighted root-mean-square timing residuals of the timing residuals of 1.23 μs, 15.5 per cent improvement compared to the total intensity timing analysis. After studying the scintillation properties of this pulsar, we put constraints on the inclination angle of the system. Based on these measurements and on χ2 mapping we put a 2σ upper limit on the companion mass (0.44 M⊙). Since this mass limit cannot reveal the nature of the companion, we further investigate the possibility of the companion to be a He WD. Applying the orbital period-mass relation for such WDs, we conclude that the mass of a He WD companion would be about 0.26±0.01 M⊙, which combined with the measured mass function and orbital inclination limits, would lead to a light pulsar mass ≤ 1.0 M⊙. This result seems unlikely based on current neutron star formation models and we therefore conclude that PSR J1933-6211 most likely has a CO WD companion, which allows for a solution with a more massive pulsar.

  6. Askaris, Asymmetry, and Small Wars: Operational Art and the German East African Campaign, 1914-1918

    DTIC Science & Technology

    2001-02-01

    Art moves through 8 the realm of the possible, but is restrained by the laws of science . The Pharaohs created some of the most awe inspiring...... Art and the German East African Campaign, 1914-1918 Unclassified 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) Adgie

  7. 20. San FranciscoOakland Bay Bridge contract recipients, April 28, 1933, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    20. San Francisco-Oakland Bay Bridge contract recipients, April 28, 1933, photographer unknown. Standing, left to right: Edward J. Schneider, Columbia Steel Corporation; C.C. Horton, Healy-Tibbitts Construction Company; Henry J. Kaiser, Bridge Builders, Inc.; Albert Huber, Clinton Construction Company; Allan McDonald, Transbay Construction Company; C.C. Carleton, Chief, Division of Contracts and Rights of Way, California Department of Public Works. Seated, left to right: Henry J. Brunnier, Consulting Engineer, Member of Consulting Board, San Francisco-Oakland Bay Bridge; Charles E. Andrew, Bridge Engineer, San Francisco-Oakland Bay Bridge; Earl Lee Kelly, Director, California Department of Public Works; Harrison S. Robinson, President, Financial ... - Salt River Bridge, Spanning Salt River at Dillon Road, Ferndale, Humboldt County, CA

  8. 17 CFR 270.14a-1 - Use of notification pursuant to regulation E under the Securities Act of 1933.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Commission adequately insures (a) that after the effective date of such notification such company will not... Securities Exchanges SECURITIES AND EXCHANGE COMMISSION (CONTINUED) RULES AND REGULATIONS, INVESTMENT COMPANY... of 1933 by a small business investment company operating under the Small Business Investment Act of...

  9. 29 CFR Appendix III to Part 1918 - The Mechanics of Conventional Cargo Gear (Non-mandatory)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...) III Appendix III to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... preventer(s) to safely support the lateral stresses generated in the boom(s) by the married falls. As the... stress in the guy(s) increases rapidly due to the increased vertical force that is generated in the guy(s...

  10. 29 CFR Appendix III to Part 1918 - The Mechanics of Conventional Cargo Gear (Non-mandatory)

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ...) III Appendix III to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... preventer(s) to safely support the lateral stresses generated in the boom(s) by the married falls. As the... stress in the guy(s) increases rapidly due to the increased vertical force that is generated in the guy(s...

  11. 29 CFR Appendix III to Part 1918 - The Mechanics of Conventional Cargo Gear (Non-mandatory)

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...) III Appendix III to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... preventer(s) to safely support the lateral stresses generated in the boom(s) by the married falls. As the... stress in the guy(s) increases rapidly due to the increased vertical force that is generated in the guy(s...

  12. 29 CFR Appendix III to Part 1918 - The Mechanics of Conventional Cargo Gear (Non-mandatory)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...) III Appendix III to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... preventer(s) to safely support the lateral stresses generated in the boom(s) by the married falls. As the... stress in the guy(s) increases rapidly due to the increased vertical force that is generated in the guy(s...

  13. 29 CFR Appendix III to Part 1918 - The Mechanics of Conventional Cargo Gear (Non-mandatory)

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ...) III Appendix III to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND... preventer(s) to safely support the lateral stresses generated in the boom(s) by the married falls. As the... stress in the guy(s) increases rapidly due to the increased vertical force that is generated in the guy(s...

  14. 29 CFR 1918.97 - First aid and lifesaving facilities. (See appendix V of this part).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 7 2010-07-01 2010-07-01 false First aid and lifesaving facilities. (See appendix V of... LONGSHORING General Working Conditions. § 1918.97 First aid and lifesaving facilities. (See appendix V of this... injury, regardless of severity, to the employer. (b) First aid. A first aid kit shall be available at or...

  15. The Würzburg Anatomical Institute and its supply of corpses (1933-1945).

    PubMed

    Blessing, Tim; Wegener, Anna; Koepsell, Hermann; Stolberg, Michael

    2012-06-01

    The Würzburg Anatomical Institute was one of the largest institutions of its kind in early 20th-century Germany. Little is known so far, however, about its history in the Third Reich. This paper presents the first results of current research on the Institute's directors Hans Petersen (1925-1940) and Curt Elze (1940-1945) and the sources from which it received its corpses during that period. For both directors there is little evidence for a marked affinity to National-Socialist ideology but a substantial degree of opportunism emerges from the surviving sources, at least in the case of Elze. Elze not only joined the NSDAP, by his own admission, without strict necessity. He also did not protest when Werner Heyde, principal medical actor in the Nazi "euthanasia" program, supplied him with 80 corpses of men and women who clearly had been murdered with carbon monoxide. The Institute's supply of corpses is analyzed based on the registers of received corpses and other, supplementary sources. Before 1933, the Würzburg Institute received most of its corpses from hospitals, old age homes. Between 1933 and 1945 some marked changes occurred. In particular, the number of corpses not only from psychiatric hospitals but also from other places of institutional care declined, presumably due, at least to a substantial degree, to "euthanasia". On the other hand, the number of corpses delivered from execution sites, prisons and Gestapo rose dramatically, reflecting the massive increase of the number of death sentences as well as, by all appearances, that of deaths from physical violence and torture in the prisons. Copyright © 2012 Elsevier GmbH. All rights reserved.

  16. The Role of Radiology in Influenza: Novel H1N1 and Lessons Learned From the 1918 Pandemic

    PubMed Central

    Mollura, Daniel J.; Morens, David M.; Taubenberger, Jeffery K.; Bray, Mike

    2012-01-01

    The pandemic of swine-origin H1N1 influenza that began in early 2009 has provided evidence that radiology can assist in the early diagnosis of severe cases, raising new opportunities for the further development of infectious disease imaging. To help define radiology’s role in present and future influenza outbreaks, it is important to understand how radiologists have responded to past epidemics and how these outbreaks influenced the development of imaging science. The authors review the role of radiology in the most severe influenza outbreak in history, the “great pandemic” of 1918, which arrived only 23 years after the discovery of x-rays. In large part because of the coincidental increase in the radiologic capacity of military hospitals for World War I, the 1918 pandemic firmly reinforced the role of radiologists as collaborators with clinicians and pathologists at an early stage in radiology’s development, in addition to producing a radical expansion of radiologic research on pulmonary infections. Radiology’s solid foundation from the 1918 experience in medical practice and research now affords significant opportunities to respond to the current H1N1 pandemic and future epidemics through similar interdisciplinary strategies that integrate imaging science with pathology, virology, and clinical studies. The broad range of current imaging capabilities will make it possible to study influenza at the cellular level, in animal models, and in human clinical trials to elucidate the pathogenesis of severe illness and improve clinical outcomes. PMID:20816630

  17. American Intervention in Russia, 1917-1918: A Study in Political-Military Relationships.

    DTIC Science & Technology

    1987-06-05

    to the British. In the Fall of 118, General William S. Graves and the 8th Infantry Division landed in Siberia as the American Siberian Expedition...CASE). Here, Americ&ns also fought a series of small unit actions that were defensive in nature. The Siberian Expedition consisted of more than 12,000...Mlissoula, Mit.: The Doughboy Historical Society and G.0.5., Inc., 1982) pp. 10-13. 2j1bid., pp. 15-19. 3Williaa S. Graves, America’s Siberian Adventure 1918

  18. Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-alpha signaling and increased severity of 1918 pandemic influenza virus infection

    USDA-ARS?s Scientific Manuscript database

    The influenza pandemic of 1918-1919 was one of the worst global pandemics in recent history. The highly pathogenic nature of the 1918 virus is thought to be mediated in part by a dysregulation of the host response, including an exacerbated pro-inflammatory cytokine response. In the present study, we...

  19. [State Hygiene Institute, 1918-1954 organisational structure, objectives and tasks].

    PubMed

    Wieckowska, E

    2001-01-01

    After Poland regained its independence in 1918, research units were set up to provide scientific assistance to the state health and epidemiological service then being created. Towards the end of 1918 The State Central Hygiene Institute was established and, following successive reorganisations, transformed into the State Hygiene Institute. It operated at Chocimska str. 24 throughout the entire pre-war period, adapting its organisational structure to current needs. As a state public-health institution, it tracked down sources of communicable diseases and the way they were spread, and conducted research to detect cases of Asian cholera and carriers of contagious diseases. It produced vaccinations of other biological products used in the treatment and prevention of epidemics and made a significant contribution to the war on communicable diseases. It also served as the central state institution in charge of inspecting the country's epidemiological condition as well as a scientific-research facility designed to maintain it at a suitable level in accordance with international norms. With various organisational modifications it survived World War Two, its continued existence being maintained by the German occupation authorities. Reactivated after the war it continues to function to this day at its old location - ulica Chocimska 24, where it serves as a scientific-research facility for health and epidemiological services transferred to a separate organisational structure after 1950. Health and sanitary stations became state institutions in charge of anti-epidemic campaigns and were responsible for the country's health and epidemiological situation. In 1954, the State Health Inspectorate co-operating with the Ministry of Health was set up. The State Hygiene Institute functions to this day and it is the supervisory, co-ordinating and scientific-research institution of the State Health and Epidemiological Service.

  20. Agent-based modeling of the spread of the 1918-1919 flu in three Canadian fur trading communities.

    PubMed

    O'Neil, Caroline A; Sattenspiel, Lisa

    2010-01-01

    Previous attempts to study the 1918-1919 flu in three small communities in central Manitoba have used both three-community population-based and single-community agent-based models. These studies identified critical factors influencing epidemic spread, but they also left important questions unanswered. The objective of this project was to design a more realistic agent-based model that would overcome limitations of earlier models and provide new insights into these outstanding questions. The new model extends the previous agent-based model to three communities so that results can be compared to those from the population-based model. Sensitivity testing was conducted, and the new model was used to investigate the influence of seasonal settlement and mobility patterns, the geographic heterogeneity of the observed 1918-1919 epidemic in Manitoba, and other questions addressed previously. Results confirm outcomes from the population-based model that suggest that (a) social organization and mobility strongly influence the timing and severity of epidemics and (b) the impact of the epidemic would have been greater if it had arrived in the summer rather than the winter. New insights from the model suggest that the observed heterogeneity among communities in epidemic impact was not unusual and would have been the expected outcome given settlement structure and levels of interaction among communities. Application of an agent-based computer simulation has helped to better explain observed patterns of spread of the 1918-1919 flu epidemic in central Manitoba. Contrasts between agent-based and population-based models illustrate the advantages of agent-based models for the study of small populations. © 2010 Wiley-Liss, Inc.

  1. Contemporary avian influenza A virus subtype H1, H6, H7, H10, and H15 hemagglutinin genes encode a mammalian virulence factor similar to the 1918 pandemic virus H1 hemagglutinin.

    PubMed

    Qi, Li; Pujanauski, Lindsey M; Davis, A Sally; Schwartzman, Louis M; Chertow, Daniel S; Baxter, David; Scherler, Kelsey; Hartshorn, Kevan L; Slemons, Richard D; Walters, Kathie-Anne; Kash, John C; Taubenberger, Jeffery K

    2014-11-18

    Zoonotic avian influenza virus infections may lead to epidemics or pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its H1 hemagglutinin was identified as a key mammalian virulence factor. A chimeric 1918 virus expressing a contemporary avian H1 hemagglutinin, however, displayed murine pathogenicity indistinguishable from that of the 1918 virus. Here, isogenic chimeric avian influenza viruses were constructed on an avian influenza virus backbone, differing only by hemagglutinin subtype expressed. Viruses expressing the avian H1, H6, H7, H10, and H15 subtypes were pathogenic in mice and cytopathic in normal human bronchial epithelial cells, in contrast to H2-, H3-, H5-, H9-, H11-, H13-, H14-, and H16-expressing viruses. Mouse pathogenicity was associated with pulmonary macrophage and neutrophil recruitment. These data suggest that avian influenza virus hemagglutinins H1, H6, H7, H10, and H15 contain inherent mammalian virulence factors and likely share a key virulence property of the 1918 virus. Consequently, zoonotic infections with avian influenza viruses bearing one of these hemagglutinins may cause enhanced disease in mammals. Influenza viruses from birds can cause outbreaks in humans and may contribute to the development of pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its main surface protein, an H1 subtype hemagglutinin, was identified as a key mammalian virulence factor. In a previous study, a 1918 virus expressing an avian H1 gene was as virulent in mice as the reconstructed 1918 virus. Here, a set of avian influenza viruses was constructed, differing only by hemagglutinin subtype. Viruses with the avian H1, H6, H7, H10, and H15 subtypes caused severe disease in mice and damaged human lung cells. Consequently, infections with avian influenza viruses bearing one of these hemagglutinins may cause enhanced disease in mammals, and therefore surveillance for human infections

  2. [Chile between pandemic: the influenza of 1918, globalization and the new medicine].

    PubMed

    López, Marcelo; Beltrán, Miriam

    2013-04-01

    In 1918 Chile met the deadly presence of the Spanish influenza pandemic twentieth century's most important. For many historians, this event is an important milestone in the historical process of the unification of the world through sickness and in which our country has been involved. In this context, this paper aims to examine how the flu broke into Chilean society and how that situation helped give new impetus to the modernization of the Chilean public health and the establishment in the 1920s to model new medicine or preventive medicine.

  3. Drought and epidemic typhus, central Mexico, 1655-1918.

    PubMed

    Burns, Jordan N; Acuna-Soto, Rudofo; Stahle, David W

    2014-03-01

    Epidemic typhus is an infectious disease caused by the bacterium Rickettsia prowazekii and transmitted by body lice (Pediculus humanus corporis). This disease occurs where conditions are crowded and unsanitary. This disease accompanied war, famine, and poverty for centuries. Historical and proxy climate data indicate that drought was a major factor in the development of typhus epidemics in Mexico during 1655-1918. Evidence was found for 22 large typhus epidemics in central Mexico, and tree-ring chronologies were used to reconstruct moisture levels over central Mexico for the past 500 years. Below-average tree growth, reconstructed drought, and low crop yields occurred during 19 of these 22 typhus epidemics. Historical documents describe how drought created large numbers of environmental refugees that fled the famine-stricken countryside for food relief in towns. These refugees often ended up in improvised shelters in which crowding encouraged conditions necessary for spread of typhus.

  4. The 1918 influenza pandemic in New York City: age-specific timing, mortality, and transmission dynamics

    PubMed Central

    Yang, Wan; Petkova, Elisaveta; Shaman, Jeffrey

    2014-01-01

    Background The 1918 influenza pandemic caused disproportionately high mortality among certain age groups. The mechanisms underlying these differences are not fully understood. Objectives To explore the dynamics of the 1918 pandemic and to identify potential age-specific transmission patterns. Methods We examined 1915–1923 daily mortality data in New York City (NYC) and estimated the outbreak duration and initial effective reproductive number (Re) for each 1-year age cohort. Results Four pandemic waves occurred from February 1918 to April 1920. The fractional mortality increase (i.e. ratio of excess mortality to baseline mortality) was highest among teenagers during the first wave. This peak shifted to 25- to 29-year-olds in subsequent waves. The distribution of age-specific mortality during the last three waves was strongly correlated (r = 0·94 and 0·86). With each wave, the pandemic appeared to spread with a comparable early growth rate but then attenuate with varying rates. For the entire population, Re estimates made assuming 2-day serial interval were 1·74 (1·27), 1·74 (1·43), 1·66 (1·25), and 1·86 (1·37), respectively, during the first week (first 3 weeks) of each wave. Using age-specific mortality, the average Re estimates over the first week of each wave were 1·62 (95% CI: 1·55–1·68), 1·68 (1·65–1·72), 1·67 (1·61–1·73), and 1·69 (1·63–1·74), respectively; Re was not significantly different either among age cohorts or between waves. Conclusions The pandemic generally caused higher mortality among young adults and might have spread mainly among school-aged children during the first wave. We propose mechanisms to explain the timing and transmission dynamics of the four NYC pandemic waves. PMID:24299150

  5. 29 CFR Appendix V to Part 1918 - Basic Elements of a First Aid Training Program (Non-mandatory)

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...-mandatory) V Appendix V to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND...) Side Stress on Boom .66(b)(3)(i) Vessel's Permanent Equipment .55 Visible Defects .66(b)(3)(ii) Cups... Related Employments .2 River Towboat .2 Small Trimming Hatch .2 Vessel .2 Vessel's Cargo Handling Gear .2...

  6. 29 CFR Appendix V to Part 1918 - Basic Elements of a First Aid Training Program (Non-mandatory)

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ...-mandatory) V Appendix V to Part 1918 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND...) Side Stress on Boom .66(b)(3)(i) Vessel's Permanent Equipment .55 Visible Defects .66(b)(3)(ii) Cups... Related Employments .2 River Towboat .2 Small Trimming Hatch .2 Vessel .2 Vessel's Cargo Handling Gear .2...

  7. Between resentment and aid: German and Austrian psychiatrist and neurologist refugees in Great Britain since 1933.

    PubMed

    Loewenau, Aleksandra

    2016-01-01

    This article is a historiographical exploration of the experiences that German and Austrian émigré psychiatrists and neurologists made in Great Britain since 1933, after the Nazi Governments in Central Europe had ousted them from their positions. When placing these occurrences in a wider historiographical perspective, the in-depth analysis provided here also describes the living and working conditions of the refugee neuroscientists on the British Isles. In particular, it looks at the very elements and issues that influenced the international forced migration of physicians and psychiatrists during the 1930s and 1940s. Only a fraction of refugee neuroscientists had however been admitted to Britain. Those lucky ones were assisted by a number of charitable, local, and academic organizations. This article investigates the rather lethargic attitude of the British government and medical circles towards German-speaking Jewish refugee neuroscientists who wished to escape Nazi Germany. It will also analyze the help that those refugees received from the academic establishment and British Jewish organizations, while likewise examining the level and extent of the relationship between social and scientific resentments in Great Britain. A special consideration will be given to the aid programs that had already began in the first year after the Nazis had seized power in Germany, with the foundation of the British Assistance Council by Sir William Henry Beveridge (1879-1963) in 1933.

  8. Pestalozzi in Dewey's Realm? Bauhaus Master Josef Albers among the German-Speaking Emigres' Colony at Black Mountain College (1933-1949)

    ERIC Educational Resources Information Center

    Fussl, Karl Heinz

    2006-01-01

    This article deals with German academic emigres who fled Hitler after 1933 and established their refuge at the American-based Black Mountain College in North Carolina, founded as an alternative to traditional institutions of higher education in that very year. Of particular consideration are the contributions of noted Bauhaus master Josef Albers…

  9. Fort Bragg Old Post Historic District Landscape Report

    DTIC Science & Technology

    2011-01-01

    Low Photinia 1933 Syringa—in variety Lilacs 1933 Native Vaccinium corymbosum Highbush Blueberry 1933 Native Viburnum—in variety Viburnums ERDC...standardized planting plan for theater, chapel, and hospital (Fort Bragg Cultural Resources). ~*""’ .... "’"""nn COIOUt:..Ulltt ..c•~«O:« Io l.\\. ~· VP~N...red to blue to violet. Some Na- tive Vaccinium corymbo- sum Highbush Blueberry Height: 6-12 ft Rounded, multi- stemmed, fairly uniform, arching

  10. Orthopaedics in Germany under the influence of National-Socialist healt-politic in the years 1933-1945.

    PubMed

    von Grabowski, Michał T W

    2015-01-01

    In the paper the health-care of physically disabled patients in Germany before, during and after the II world war are discussed. The circumstances of introduction of "Racial-Hygiene" - laws and orthopedic indications for the sterilization and euthanasia are described. Patients with severe physical and mental disabilities were potential candidates for annihilation. The tragic fate of jewish physicians is remembered. The activity of board of the German Orthopeadic Society (DOG) in the years 1933-1945 is described and critically analysed.

  11. Scientific triumphalism and learning from facts: bacteriology and the "Spanish flu" challenge of 1918.

    PubMed

    Tognotti, Eugenia

    2003-04-01

    The devastating influenza pandemic known as 'Spanish flu', which killed at least 20 million people all over the world in 1918, was responsible for the first bitter blow inflicted on triumphant bacteriology, fortified by the series of resounding successes achieved in identifying the pathogenic agents of terrible diseases such as anthrax, cholera, tuberculosis, plague, and syphilis. Over-confidence and the idea, born of the Pasteur revolution, that every infectious disease was caused by a bacterium, had led the scientific community to accept the theory put forward by the German bacteriologist, Richard Pfeiffer, who, in 1892, believed he had identified the pathogenic influenza agent in a bacterium, Haemophilus influenzae. But, while the most appalling epidemic ever to sweep through the world since the 'Black Death' of the 1300s was still raging, the scientific community had to admit that influenza originated not from a microbe, but from a virus. This article aims to reconstruct the enlightening and little-known cultured/scientific events and issues of the dramatic crisis that bacteriology experienced in the autumn of 1918, with the consequent simultaneous collapse of both the 'Pfeiffer doctrine' on the microbial origin of influenza and the illusion of a world free of infectious diseases. This was an illusion destined to surface again at the end of the century and collapse with the advent of AIDS.

  12. Spatial dynamics of the 1918 influenza pandemic in England, Wales and the United States.

    PubMed

    Eggo, Rosalind M; Cauchemez, Simon; Ferguson, Neil M

    2011-02-06

    There is still limited understanding of key determinants of spatial spread of influenza. The 1918 pandemic provides an opportunity to elucidate spatial determinants of spread on a large scale. To better characterize the spread of the 1918 major wave, we fitted a range of city-to-city transmission models to mortality data collected for 246 population centres in England and Wales and 47 cities in the US. Using a gravity model for city-to-city contacts, we explored the effect of population size and distance on the spread of disease and tested assumptions regarding density dependence in connectivity between cities. We employed Bayesian Markov Chain Monte Carlo methods to estimate parameters of the model for population, infectivity, distance and density dependence. We inferred the most likely transmission trees for both countries. For England and Wales, a model that estimated the degree of density dependence in connectivity between cities was preferable by deviance information criterion comparison. Early in the major wave, long distance infective interactions predominated, with local infection events more likely as the epidemic became widespread. For the US, with fewer more widely dispersed cities, statistical power was lacking to estimate population size dependence or the degree of density dependence, with the preferred model depending on distance only. We find that parameters estimated from the England and Wales dataset can be applied to the US data with no likelihood penalty.

  13. Contemporary Avian Influenza A Virus Subtype H1, H6, H7, H10, and H15 Hemagglutinin Genes Encode a Mammalian Virulence Factor Similar to the 1918 Pandemic Virus H1 Hemagglutinin

    PubMed Central

    Qi, Li; Pujanauski, Lindsey M.; Davis, A. Sally; Schwartzman, Louis M.; Chertow, Daniel S.; Baxter, David; Scherler, Kelsey; Hartshorn, Kevan L.; Slemons, Richard D.; Walters, Kathie-Anne; Kash, John C.

    2014-01-01

    ABSTRACT Zoonotic avian influenza virus infections may lead to epidemics or pandemics. The 1918 pandemic influenza virus has an avian influenza virus-like genome, and its H1 hemagglutinin was identified as a key mammalian virulence factor. A chimeric 1918 virus expressing a contemporary avian H1 hemagglutinin, however, displayed murine pathogenicity indistinguishable from that of the 1918 virus. Here, isogenic chimeric avian influenza viruses were constructed on an avian influenza virus backbone, differing only by hemagglutinin subtype expressed. Viruses expressing the avian H1, H6, H7, H10, and H15 subtypes were pathogenic in mice and cytopathic in normal human bronchial epithelial cells, in contrast to H2-, H3-, H5-, H9-, H11-, H13-, H14-, and H16-expressing viruses. Mouse pathogenicity was associated with pulmonary macrophage and neutrophil recruitment. These data suggest that avian influenza virus hemagglutinins H1, H6, H7, H10, and H15 contain inherent mammalian virulence factors and likely share a key virulence property of the 1918 virus. Consequently, zoonotic infections with avian influenza viruses bearing one of these hemagglutinins may cause enhanced disease in mammals. PMID:25406382

  14. Drought and Epidemic Typhus, Central Mexico, 1655–1918

    PubMed Central

    Acuna-Soto, Rudofo; Stahle, David W.

    2014-01-01

    Epidemic typhus is an infectious disease caused by the bacterium Rickettsia prowazekii and transmitted by body lice (Pediculus humanus corporis). This disease occurs where conditions are crowded and unsanitary. This disease accompanied war, famine, and poverty for centuries. Historical and proxy climate data indicate that drought was a major factor in the development of typhus epidemics in Mexico during 1655–1918. Evidence was found for 22 large typhus epidemics in central Mexico, and tree-ring chronologies were used to reconstruct moisture levels over central Mexico for the past 500 years. Below-average tree growth, reconstructed drought, and low crop yields occurred during 19 of these 22 typhus epidemics. Historical documents describe how drought created large numbers of environmental refugees that fled the famine-stricken countryside for food relief in towns. These refugees often ended up in improvised shelters in which crowding encouraged conditions necessary for spread of typhus. PMID:24564928

  15. Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic.

    PubMed

    Chien, Yu-Wen; Klugman, Keith P; Morens, David M

    2010-12-01

    Most deaths in the 1918 influenza pandemic were caused by secondary bacterial pneumonia. We performed a systematic review and reanalysis of studies of bacterial vaccine efficacy (VE) in preventing pneumonia and mortality among patients with influenza during the 1918 pandemic. A meta-analysis of 6 civilian studies of mixed killed bacterial vaccines containing pneumococci identified significant heterogeneity among studies and estimated VE at 34% (95% confidence interval [CI], 19%-47%) in preventing pneumonia and 42% (95% CI, 18%-59%) in reducing case fatality rates among patients with influenza, using random-effects models. Using fixed-effect models, the pooled VE from 3 military studies was 59% (95% CI, 43%-70%) for pneumonia and 70% (95% CI, 50%-82%) for case fatality. Military studies showed less heterogeneity and may provide more accurate results than civilian studies, given the potential biases in the included studies. Findings of 1 military study using hemolytic streptococci also suggested that there was significant protection. Despite significant methodological problems, the systematic biases in these studies do not exclude the possibilities that whole-cell inactivated pneumococcal vaccines may confer cross-protection to multiple pneumococcal serotypes and that bacterial vaccines may play a role in preventing influenza-associated pneumonia.

  16. Spatial dynamics of the 1918 influenza pandemic in England, Wales and the United States

    PubMed Central

    Eggo, Rosalind M.; Cauchemez, Simon; Ferguson, Neil M.

    2011-01-01

    There is still limited understanding of key determinants of spatial spread of influenza. The 1918 pandemic provides an opportunity to elucidate spatial determinants of spread on a large scale. To better characterize the spread of the 1918 major wave, we fitted a range of city-to-city transmission models to mortality data collected for 246 population centres in England and Wales and 47 cities in the US. Using a gravity model for city-to-city contacts, we explored the effect of population size and distance on the spread of disease and tested assumptions regarding density dependence in connectivity between cities. We employed Bayesian Markov Chain Monte Carlo methods to estimate parameters of the model for population, infectivity, distance and density dependence. We inferred the most likely transmission trees for both countries. For England and Wales, a model that estimated the degree of density dependence in connectivity between cities was preferable by deviance information criterion comparison. Early in the major wave, long distance infective interactions predominated, with local infection events more likely as the epidemic became widespread. For the US, with fewer more widely dispersed cities, statistical power was lacking to estimate population size dependence or the degree of density dependence, with the preferred model depending on distance only. We find that parameters estimated from the England and Wales dataset can be applied to the US data with no likelihood penalty. PMID:20573630

  17. 17 CFR 239.16b - Form S-8, for registration under the Securities Act of 1933 of securities to be offered to...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... under the Securities Act of 1933 of securities to be offered to employees pursuant to employee benefit... employee benefit plans. (a) Any registrant that, immediately prior to the time of filing a registration... benefit plan. The form also is available for the exercise of employee benefit plan options by an employee...

  18. [German neurology and neurologists during the Third Reich: Preconditions and general framework before and after 1933].

    PubMed

    Martin, M; Karenberg, A; Fangerau, H

    2016-08-01

    This article focuses on the institutional development of neurology in Germany up to the rise to power of the National Socialists and the radical sociopolitical changes after 1933. A wide range of scattered secondary literature was assessed and evaluated. Additionally, some original sources are literally quoted and interpreted according to the context. Since the end of the nineteenth century a complicated process of separation from internal medicine and psychiatry led to the formation of a self-conscious discipline of neurology. The first generation of German neurologists succeeded in founding the German Journal for Neurology ("Deutsche Zeitschrift für Nervenheilkunde") in 1890 and their own neurological association, the Society of German Neurologists ("Gesellschaft Deutscher Nervenärzte", GDN) in 1907. On an international scale, however, the institutional implementation of neurology with only a small number of chairs and few neurology departments remained more than modest. The ambitions for autonomy ended 2 years after the change of power in 1933. Regulatory interventions by the government and psychiatric interests led to the fusion of the GDN with the psychiatric specialist society, the new association being called the Society of German Neurologists and Psychiatrists ("Gesellschaft Deutscher Neurologen und Psychiater", GDNP) in 1935. In this group psychiatrists dominated the discourse. The expulsion, imprisonment and murder of physicians declared as non-Aryan or Jewish along with the forced consolidation ("Gleichschaltung") at the universities prompted profound changes in medical and academic life. It remains an ongoing challenge of neurological historical research to measure the impact of this upheaval on the few neurology departments in hospitals and private practices.

  19. Nursery Schools or Nursery Classes? Choosing and Failing to Choose between Policy Alternatives in Nursery Education in England, 1918-1972

    ERIC Educational Resources Information Center

    Palmer, Amy

    2016-01-01

    This article analyses early years education policy in England from 1918 to 1972, applying the theoretical ideas of John Kingdon. Throughout this period, the educational needs of young children were a low political priority, but they did occasionally rise on the agenda. When the issue gained prominence, politicians considered two key policy…

  20. Exceptionally high mortality rate of the 1918 influenza pandemic in the Brazilian naval fleet.

    PubMed

    Schuck-Paim, Cynthia; Shanks, G Dennis; Almeida, Francisco E A; Alonso, Wladimir J

    2013-01-01

    The naval experience with the 1918 pandemic during World War I remains underexplored despite its key role on the pandemic's global diffusion and the epidemiological interest of isolated and relatively homogeneous populations. The pandemic outbreak in the Brazilian naval fleet is of particular interest both because of its severity and the fact that it was the only Latin American military force deployed to war. To study the mortality patterns of the pandemic in the Brazilian fleet sent to patrol the West African coast in 1918. We investigated mortality across vessels, ranks, and occupations based on official population and mortality records from the Brazilian Navy Archives. The outbreak that swept this fleet included the highest influenza mortality rate on any naval ship reported to date. Nearly 10% of the crews died, with death rates reaching 13-14% on two destroyers. While overall mortality was lower for officers, stokers and engineer officers were significantly more likely to die from the pandemic, possibly due to the pulmonary damage from constant exposure to the smoke and coal dust from the boilers. The fatality patterns observed provide valuable data on the conditions that can exacerbate the impact of a pandemic. While the putative lack of exposure to a first pandemic wave may have played a role in the excessive mortality observed in this fleet, our results indicate that strenuous labor conditions, dehydration, and exposure to coal dust were major risk factors. The unequal death rates among vessels remain an open question. © 2012 Blackwell Publishing Ltd.

  1. 'National Hero and Very Queer Fish': Empire, Sexuality and the British Remembrance of General Gordon, 1918-72.

    PubMed

    Jones, Max

    2015-01-01

    This article presents the first detailed study of General Gordon's remembrance in Britain between 1918 and 1972. Previous scholars have exaggerated the impact of Lytton Strachey's Eminent Victorians (1918). Strachey damaged Gordon's reputation, but part one reveals how several commentators forcefully rebutted Eminent Victorians; official commemorations, books, radio plays, and films celebrated Gordon in the 1930s, as empire featured prominently in mass culture. Didactic uses of his example by the state diminished after 1945, but parts 2 and 3 show how writers used Gordon's story to engage with new debates about Britain's role in the world, immigration and sexuality. The article reveals how a fascination with the sexuality of heroes inspired men as diverse as Viscount Robin Maugham and East End gangster Ronnie Kray to identify with Gordon. Maugham's works and the feature film Khartoum (1966) expressed nostalgia for empire during decolonization, but American screenwriter Robert Ardrey also drew on his experiences in the Congo to present a dark vision of African savagery in Khartoum, a vision performed at Pinewood studios by black immigrants from London's slums. The article questions Edward Berenson's emphasis on the 'charismatic aura' of heroes, emphasizing instead the diversity of engagements inspired through different genre.

  2. Absolute and geometric parameters of contact binary V1918 Cyg

    NASA Astrophysics Data System (ADS)

    Gürol, B.

    2016-08-01

    We present the results of our investigation on the geometrical and physical parameters of the W UMa type binary system V1918 Cyg from analyzed CCD (BVR) light curves and radial velocity data. We used the photometric data published by Yang et al. (2013) and spectroscopic data obtained in 2012 at TUBITAK National Observatory (TUG). The light and radial velocity observations were analyzed simultaneously by using the Wilson-Devinney (2015 revision) code to obtain absolute and geometrical parameters of the system. It is confirmed that the system is an A-type W UMa as indicated by Yang et al. (2013). Combining our spectroscopic data with the photometric solution we derived masses and radii of the eclipsing system as M1 = 1.302M⊙ , M2 = 0.362M⊙ , R1 = 1.362R⊙ and R2 = 0.762R⊙ . Finally, we discuss the evolutionary status of the system.

  3. The rise and fall of rabies in Japan: A quantitative history of rabies epidemics in Osaka Prefecture, 1914-1933.

    PubMed

    Kurosawa, Aiko; Tojinbara, Kageaki; Kadowaki, Hazumu; Hampson, Katie; Yamada, Akio; Makita, Kohei

    2017-03-01

    Japan has been free from rabies since the 1950s. However, during the early 1900s several large-scale epidemics spread throughout the country. Here we investigate the dynamics of these epidemics between 1914 and 1933 in Osaka Prefecture, using archival data including newspapers. The association between dog rabies cases and human population density was investigated using Mixed-effects models and epidemiological parameters such as the basic reproduction number (R0), the incubation and infectious period and the serial interval were estimated. A total of 4,632 animal rabies cases were reported, mainly in dogs (99.0%, 4,584 cases) during two epidemics from 1914 to 1921, and 1922 to 1933 respectively. The second epidemic was larger (3,705 cases) than the first (879 cases), but had a lower R0 (1.50 versus 2.42). The first epidemic was controlled through capture of stray dogs and tethering of pet dogs. Dog mass vaccination began in 1923, with campaigns to capture stray dogs. Rabies in Osaka Prefecture was finally eliminated in 1933. A total of 3,805 rabid dog-bite injuries, and 75 human deaths were reported. The relatively low incidence of human rabies, high ratio of post-exposure vaccines (PEP) and bite injuries by rabid dogs (minimum 6.2 to maximum 73.6, between 1924 and 1928), and a decline in the proportion of bite victims that developed hydrophobia over time (slope = -0.29, se = 3, p < 0.001), indicated that increased awareness and use of PEP might have prevented disease. Although significantly more dog rabies cases were detected at higher human population densities (slope = 0.66, se = 0.03, p < 0.01), there were fewer dog rabies cases detected per capita (slope = -0.34, se = 0.03, p < 0.01). We suggest that the combination of mass vaccination and restriction of dog movement enabled by strong legislation was key to eliminate rabies. Moreover, the prominent role of the media in both reporting rabies cases and efforts to control the disease likely contributed to

  4. Physical anthropology in 1918 and the founding of the U.S. journal.

    PubMed

    Little, Michael A

    2018-04-01

    In 1918, the first issue of the American Journal of Physical Anthropology was prepared and distributed by Aleš Hrdlička, the Curator of Physical Anthropology at the Smithsonian Institution. This was a singular act, both in the general and specific sense. It was the first journal of physical anthropology published in the United States, and it was a sole effort by Hrdlička, who was committed to promoting and recognizing physical anthropology as a new science in America. On this 100th anniversary of the founding of the journal, Hrdlička's efforts were successful: physical/biological anthropology is a strong and timely discipline that represents a major area of scientific research today. © 2018 Wiley Periodicals, Inc.

  5. The II Italian Corps Deployment on the Western Front during the First World War (April 1918-May 1919)

    DTIC Science & Technology

    2015-06-12

    experience of the Italian Armed Forces. In the last two centuries, significant origins of wars fought with allies are: 1. Common enemies, as with the Italian...result of the Paris conference in December 1917, significant 4 David Trask, The AEF and Coalition...on 16 December 1917. The formal closure of the Eastern Front, which became effective with the Treaty of Brest -Litovsk on 3 March 1918, freed a

  6. A note on the history of the Norwegian Psychoanalytic Society from 1933 to 1945.

    PubMed

    Anthi, Per; Haugsgjerd, Svein

    2013-08-01

    The Norwegian analysts, who were trained in Berlin before 1933, were drawn into a struggle against fascism, informed by politically leftist analysts who worked at the Berlin Institute. The Norwegian group, including the analysts Wilhelm Reich and Otto Fenichel, were committed to Marxist or social democratic ideologies in order to fight down fascism and Nazism. They were a source of inspiration but also of conflict. After the war the leadership of the IPA was sceptical about the Norwegian group because of its former connections with Die Linke, as well as its relations with Wilhelm Reich. This paper in part considers the courageous efforts of Nic Waal, whom Ernest Jones used as a delegate and courier to solve problems for the IPA and who was unjustly treated after the war. Copyright © 2013 Institute of Psychoanalysis.

  7. The rise and fall of rabies in Japan: A quantitative history of rabies epidemics in Osaka Prefecture, 1914–1933

    PubMed Central

    Kurosawa, Aiko; Tojinbara, Kageaki; Kadowaki, Hazumu; Hampson, Katie; Yamada, Akio

    2017-01-01

    Japan has been free from rabies since the 1950s. However, during the early 1900s several large-scale epidemics spread throughout the country. Here we investigate the dynamics of these epidemics between 1914 and 1933 in Osaka Prefecture, using archival data including newspapers. The association between dog rabies cases and human population density was investigated using Mixed-effects models and epidemiological parameters such as the basic reproduction number (R0), the incubation and infectious period and the serial interval were estimated. A total of 4,632 animal rabies cases were reported, mainly in dogs (99.0%, 4,584 cases) during two epidemics from 1914 to 1921, and 1922 to 1933 respectively. The second epidemic was larger (3,705 cases) than the first (879 cases), but had a lower R0 (1.50 versus 2.42). The first epidemic was controlled through capture of stray dogs and tethering of pet dogs. Dog mass vaccination began in 1923, with campaigns to capture stray dogs. Rabies in Osaka Prefecture was finally eliminated in 1933. A total of 3,805 rabid dog-bite injuries, and 75 human deaths were reported. The relatively low incidence of human rabies, high ratio of post-exposure vaccines (PEP) and bite injuries by rabid dogs (minimum 6.2 to maximum 73.6, between 1924 and 1928), and a decline in the proportion of bite victims that developed hydrophobia over time (slope = -0.29, se = 3, p < 0.001), indicated that increased awareness and use of PEP might have prevented disease. Although significantly more dog rabies cases were detected at higher human population densities (slope = 0.66, se = 0.03, p < 0.01), there were fewer dog rabies cases detected per capita (slope = -0.34, se = 0.03, p < 0.01). We suggest that the combination of mass vaccination and restriction of dog movement enabled by strong legislation was key to eliminate rabies. Moreover, the prominent role of the media in both reporting rabies cases and efforts to control the disease likely contributed to

  8. Disparities in influenza mortality and transmission related to sociodemographic factors within Chicago in the pandemic of 1918

    PubMed Central

    Grantz, Kyra H.; Rane, Madhura S.; Salje, Henrik; Glass, Gregory E.; Schachterle, Stephen E.; Cummings, Derek A. T.

    2016-01-01

    Social factors have been shown to create differential burden of influenza across different geographic areas. We explored the relationship between potential aggregate-level social determinants and mortality during the 1918 influenza pandemic in Chicago using a historical dataset of 7,971 influenza and pneumonia deaths. Census tract-level social factors, including rates of illiteracy, homeownership, population, and unemployment, were assessed as predictors of pandemic mortality in Chicago. Poisson models fit with generalized estimating equations (GEEs) were used to estimate the association between social factors and the risk of influenza and pneumonia mortality. The Poisson model showed that influenza and pneumonia mortality increased, on average, by 32.2% for every 10% increase in illiteracy rate adjusted for population density, homeownership, unemployment, and age. We also found a significant association between transmissibility and population density, illiteracy, and unemployment but not homeownership. Lastly, analysis of the point locations of reported influenza and pneumonia deaths revealed fine-scale spatiotemporal clustering. This study shows that living in census tracts with higher illiteracy rates increased the risk of influenza and pneumonia mortality during the 1918 influenza pandemic in Chicago. Our observation that disparities in structural determinants of neighborhood-level health lead to disparities in influenza incidence in this pandemic suggests that disparities and their determinants should remain targets of research and control in future pandemics. PMID:27872284

  9. [Historical Review of Cesarean Section at King's Maternity Hospital and Midwifery School Zagreb 1908-1918].

    PubMed

    Habek, D; Kruhak, V

    2016-04-01

    This article presents a historical review of the performance of 23 cesarean sections at the King’s Maternity Hospital and Midwifery School in Zagreb during the 1908-1918 period. Following prenatal screening by midwives and doctors in the hospital, deliveries in high risk pregnant women were performed at maternity hospitals, not at home. The most common indication for cesarean section was narrowed pelvis in 65.2% of women, while postpartum febrile condition was the most common complication in the puerperium. Maternal mortality due to sepsis after the procedure was 8.69% and overall perinatal mortality was 36.3% (stillbirths and early neonatal deaths).

  10. Cal Tech's Program in Meteorology: 1933-1948.

    NASA Astrophysics Data System (ADS)

    Lewis, J. M.

    1994-01-01

    The California Institute of Technology (Cal Tech) established a course of study in meteorology in 1933. It was intimately tied to the upsurge of activity in commercial and military aviation that occurred in the period between the world wars. The tragic crash of the airship U.S.S. Akron provided the stimulus for including meteorology as a subprogram in the aeronautics department at Cal Tech. Thoodore von K´rm´n, head of the department and director of the school's Guggenheim Aeronautics Laboratory, masterminded the design of the program and geared it toward the solution of practical problems using the principles of dynamic meteorology. One of his doctoral students, Irving Krick, was groomed to develop the program.Robert Millikan, head of the institute, fostered an approach to science that encouraged the faculty to consuit and work with industry. In this environment, Krick established links with aviation, motion picture studios, and public utilities that would set the stage for the research thrust in meteorology. The program was primarily designed for training at the master' degree level, and a significant number of the graduates became entrepreneurs in meteorology. Based on letters of reminiscence and oral histories from some of these consulting meteorologists, it has been concluded that the Millikan/von K´rm´n philosophy of science played an important part in directing the meteorologists into the private sector.Following World War II, Lee DuBridge replaced Millikan as head of the institute. DuBridge's efforts were directed toward making the small elite school scientifically competitive in the changed conditions of a postwar world. In this climate, the merging of private business with academic work fell into disfavor. Without champions such as Millikan and von K´rm´n,the meteorology program was unable to survive.

  11. Sparking-out optimization while surface grinding aluminum alloy 1933T2 parts using fuzzy logic

    NASA Astrophysics Data System (ADS)

    Soler, Ya I.; Salov, V. M.; Kien Nguyen, Chi

    2018-03-01

    The article presents the results of a search for optimal sparing-out strokes when surface grinding aluminum parts by high-porous wheels Norton of black silicon carbide 37C80K12VP using fuzzy logic. The topography of grinded surface is evaluated according to the following parameters: roughness – Ra, Rmax, Sm; indicators of flatness deviation – EFEmax, EFEa, EFEq; microhardness HV, each of these parameters is represented by two measures of position and dispersion. The simulation results of fuzzy logic in the Matlab medium establish that during the grinding of alloy 1933T2, the best integral performance evaluation of sparking-out was given to two double-strokes (d=0.827) and the worst – to three ones (d=0.405).

  12. A geographic analysis of population density thresholds in the influenza pandemic of 1918-19.

    PubMed

    Chandra, Siddharth; Kassens-Noor, Eva; Kuljanin, Goran; Vertalka, Joshua

    2013-02-20

    Geographic variables play an important role in the study of epidemics. The role of one such variable, population density, in the spread of influenza is controversial. Prior studies have tested for such a role using arbitrary thresholds for population density above or below which places are hypothesized to have higher or lower mortality. The results of such studies are mixed. The objective of this study is to estimate, rather than assume, a threshold level of population density that separates low-density regions from high-density regions on the basis of population loss during an influenza pandemic. We study the case of the influenza pandemic of 1918-19 in India, where over 15 million people died in the short span of less than one year. Using data from six censuses for 199 districts of India (n=1194), the country with the largest number of deaths from the influenza of 1918-19, we use a sample-splitting method embedded within a population growth model that explicitly quantifies population loss from the pandemic to estimate a threshold level of population density that separates low-density districts from high-density districts. The results demonstrate a threshold level of population density of 175 people per square mile. A concurrent finding is that districts on the low side of the threshold experienced rates of population loss (3.72%) that were lower than districts on the high side of the threshold (4.69%). This paper introduces a useful analytic tool to the health geographic literature. It illustrates an application of the tool to demonstrate that it can be useful for pandemic awareness and preparedness efforts. Specifically, it estimates a level of population density above which policies to socially distance, redistribute or quarantine populations are likely to be more effective than they are for areas with population densities that lie below the threshold.

  13. "De-humanised females and Amazonians": British wartime fashion and its representation in Home chat, 1914-1918.

    PubMed

    Buckley, Cheryl

    2002-01-01

    Popular representations of the fashionably dressed female body between 1914 and 1918 were highly contradictory and, as this essay will show, were sharply delineated in Home Chat, one of a growing number of relatively new women's magazines which addressed the needs of an expanding skilled working-class and lower-middle-class female readership. Aiming to provide women with practical advice about all aspects of their daily lives, from the traditional concerns of fashion and beauty, marriage and children, to the more contentious issue of women's aspirations beyond the home, Home Chat was uniquely placed to reflect shifting gender and class relations.

  14. Educational Theory and Practice in Post-Revolutionary Times: The European Academic Debate on the Experimental Schools in Hamburg (1919-1933) in the 1930s and 1970s

    ERIC Educational Resources Information Center

    Roith, Christian

    2014-01-01

    After the revolution in 1918, many reformist teachers were convinced that they could put into practice their dreams of a free and independent school in a democratic republic. Four state schools in Hamburg became anti-authoritarian school communities, in which teachers, parents and students experimented with revolutionary concepts of education. For…

  15. ['There is a need for women doctors to join forces': Dutch Association of Women Physicians, 1933-1998].

    PubMed

    Griffioen, F M

    1999-05-29

    After a history of some years, the Dutch Association of Medical Women (VNVA) was founded in 1933. The aim of the Association was to promote the interests of women doctors. At that time about 5% of the physicians were women. Their position on the labour market was not at all equal to that of their male colleagues. In 1949 some VNVA members played an important part in stimulating the recognition of women's interests by publishing on anticonception in this journal. It is still necessary to pay attention to equal opportunities for women doctors. Besides, promotion of a sex-sensitive health care was added to the mission statement. The Association nowadays has more than 2600 members.

  16. Genomic Profiling of Tumor Necrosis Factor Alpha (TNF-α) Receptor and Interleukin-1 Receptor Knockout Mice Reveals a Link between TNF-α Signaling and Increased Severity of 1918 Pandemic Influenza Virus Infection▿ †

    PubMed Central

    Belisle, Sarah E.; Tisoncik, Jennifer R.; Korth, Marcus J.; Carter, Victoria S.; Proll, Sean C.; Swayne, David E.; Pantin-Jackwood, Mary; Tumpey, Terrence M.; Katze, Michael G.

    2010-01-01

    The influenza pandemic of 1918 to 1919 was one of the worst global pandemics in recent history. The highly pathogenic nature of the 1918 virus is thought to be mediated in part by a dysregulation of the host response, including an exacerbated proinflammatory cytokine response. In the present study, we compared the host transcriptional response to infection with the reconstructed 1918 virus in wild-type, tumor necrosis factor (TNF) receptor-1 knockout (TNFRKO), and interleukin-1 (IL-1) receptor-1 knockout (IL1RKO) mice as a means of further understanding the role of proinflammatory cytokine signaling during the acute response to infection. Despite reported redundancy in the functions of IL-1β and TNF-α, we observed that reducing the signaling capacity of each of these molecules by genetic disruption of their key receptor genes had very different effects on the host response to infection. In TNFRKO mice, we found delayed or decreased expression of genes associated with antiviral and innate immune signaling, complement, coagulation, and negative acute-phase response. In contrast, in IL1RKO mice numerous genes were differentially expressed at 1 day postinoculation, including an increase in the expression of genes that contribute to dendritic and natural killer cell processes and cellular movement, and gene expression profiles remained relatively constant at later time points. We also observed a compensatory increase in TNF-α expression in virus-infected IL1RKO mice. Our data suggest that signaling through the IL-1 receptor is protective, whereas signaling through the TNF-α receptor increases the severity of 1918 virus infection. These findings suggest that manipulation of these pathways may have therapeutic benefit. PMID:20926563

  17. [Epidemics in the news in Portugal: cholera, plague, typhus, influenza and smallpox, 1854-1918].

    PubMed

    de Almeida, Maria Antónia Pires

    2014-01-01

    In severe health crisis like those of 1854-1856, 1899 and 1918, especially in Porto, where cholera morbus, the bubonic plague, typhus fever, pneumonic influenza and smallpox killed high percentages of the population, the images of the epidemics in the press enable us to identify the scientific knowledge in a country considered peripheral, but which had studies and personnel specialized at the most advanced levels for the time. A database of 6,700 news items and announcements reveals the medical and pharmaceutical knowledge of the second half of the nineteenth and early twentieth centuries, the way it was transmitted and disclosed to the public and the solutions offered by the health authorities. Hygiene was consistently highlighted in the news and announcements.

  18. The 16th International Geological Congress, Washington, 1933

    USGS Publications Warehouse

    Nelson, C.M.

    2009-01-01

    In 1933, the International Geological Congress (IGC) returned to the United States of America (USA) for its sixteenth meeting, forty-two years after the 5th IGC convened in Washington. The Geological Society of America and the U.S. Geological Survey (USGS) supplied the major part of the required extra-registration funding after the effects of the Great Depression influenced the 72th U.S. Congress not to do so. A reported 1, 182 persons or organizations, representing fifty-four countries, registered for the 16 th IGC and thirty-four countries sent 141 official delegates. Of the total number of registrants, 665 actually attended the meeting; 500 came from the USA; and fifteen had participated in the 5th IGC. The 16 th Meeting convened in the U.S. Chamber of Commerce Building from 22 to 29 July. The eighteen half-day scientific sections-orogenesis (four), major divisions of the Paleozoic (three), miscellaneous (three), batholiths and related intrusives (two), arid-region geomorphic processes and products (one), fossil man and contemporary faunas (one), geology of copper and other ore deposits (one), geology of petroleum (one), measuring geologic time (one), and zonal relations of metalliferous deposits (one)-included 166 papers, of which fifty (including several of the key contributions) appeared only by title. The Geological Society of Washington, the National Academy of Sciences, and the U.S. Bureau of Mines hosted or contributed to evening presentations or receptions. Twenty-eight of the 16th IGC's thirty new guidebooks and one new USGS Bulletin aided eight pre-meeting, seven during-meeting, and four post-meeting field trips of local, regional, or national scope. The remaining two new guidebooks outlined the USA's structural geology and its stratigraphic nomenclature. The 16th IGC published a two-volume monograph on the world's copper resources (1935) and a two-volume report of its proceedings (1936).

  19. Einstein's cosmology review of 1933: a new perspective on the Einstein-de Sitter model of the cosmos

    NASA Astrophysics Data System (ADS)

    O'Raifeartaigh, Cormac; O'Keeffe, Michael; Nahm, Werner; Mitton, Simon

    2015-09-01

    We present a first English translation and analysis of a little-known review of relativistic cosmology written by Albert Einstein in late 1932. The article, which was published in 1933 in a book of Einstein papers translated into French, contains a substantial review of static and dynamic relativistic models of the cosmos, culminating in a discussion of the Einstein-de Sitter model. The article offers a valuable contemporaneous insight into Einstein's cosmology in the early 1930s and confirms that his interest lay in the development of the simplest model of the cosmos that could account for observation. The article also confirms that Einstein did not believe that simplified relativistic models could give an accurate description of the early universe.

  20. [Public health and agrarian liberal politics in Spain: the Rural Health Bureau (1910-1918).].

    PubMed

    Rodríguez-Ocaña, Esteban

    2010-01-01

    This paper reviews the meaning of the Rural Health Bureau (1910-1918) for the history of Spanish public health, thanks to a wealth of previously unknown sources found through a systematic search through medical journals of the time and the Bulletin of the national department of Agriculture. The Bureau was dependent of the Ministry of Development, in the same way as the competences on animal health. It aimed to provide a public health rationale for a plan of agrarian infrastructures, a goal resolved into a huge task of surveillance on hookworm disease, malaria, water supplies, and diet. Thus it becomes a perfect paradigm of the Spanish Liberal tradition of promoting information instead than actual changes into society, as well as a needed complement to the hydraulic policy sponsored by Rafael Gasset.

  1. [Workers with signs of smallpox in the collection of Regional Office of Labor, Rio Grande do Sul, 1933-1944].

    PubMed

    Lopes, Aristeu Elisandro Machado

    2016-01-01

    Work Register Booklet was created in Brazil in 1932. Soon, Regional Labor Inspectorates emerged - after renamed as Regional Office of Labor. In Rio Grande do Sul, this office was settled in 1933 in Porto Alegre. Procedures for making this booklet consisted of filling a professional qualification form with workers' personal and professional information. One of the fields consisted of requester's distinguishing signs, like visible marks and lack of limbs. The purpose of this article is to analyse the presence of one of these distinguishing signs. We use 3x4cm photos of workers who presented smallpox signs, as well as other information written in the fields of their forms.

  2. Red-billed Leiothrix (Leiothrix lutea)

    USGS Publications Warehouse

    Male, Timothy D.; Fancy, Steven G.; Ralph, C. John

    1998-01-01

    Known in the cage bird trade as the Japanese Hill-Robin, Peking Robin, or Peking Nightingale, the Red-billed Leiothrix was first imported into the Hawaiian Islands in 1911 ( Fisher and Baldwin 1947 ), with intentional releases to the wild occurring after 1918 ( Caum 1933 ). A native of Southeast Asia, southern China, and the Himalayan regions of India, this species is a medium-sized, green and yellow babbler with a conspicuous red bill and strongly notched tail. The species is extremely active, but individuals are somewhat secretive and difficult to see as they flit around in the understory, often in small groups. The Red-billed Leiothrix is found in a wide variety of habitats in the Hawaiian Islands, including both native and exotic forests from sea level to near mountain summits exceeding 4,000 m elevation.

  3. U.S. Army Chemical Corps Historical Studies, Gas Warfare in World War I: The 5th Division Captures Frapelle, August 1918

    DTIC Science & Technology

    1958-03-01

    U. S . ARMY CHEMICAL CORPS HISTORICAL STUDIES GAS WARFARE IN WORLD WAR I THE 5t1h DIVISION CAPTURES FRAPELLF, 00 August 1918 CTD Offce t e Chef Ch mal...j JNSPECrrr / D~iJ f ; t t] GA o WARFARE IN WORLD WAR I By - --------- St ixdy Number 7 t:a . • ’ I : : . .. s U.S. ARMY CHEIICAL CORPS [ist...Analysi s Concerning the Weight of Shell . . . . . . . ... . 38 The Cost of Frapelle . . . . . . . . . . . .. 41 Medical Department Comments

  4. [Red Cross hospital in Krapina, during the First world war from 1914 to 1918].

    PubMed

    Fures, Rajko; Habek, Dubravko; Kozina, Drago

    2016-08-01

    Red Cross Hospital in Krapina, during the First World War, was active from 1914 to 1918. Hospital led by Dr. Mirko Crkvenac, oriented humanist. The hospital is operated thanks to the help of municipalities and citizens. The hospital staff concern is for civilian and military victims of the First World War. Dr. Crkvenac, with the support of the City of Krapina and Mayor Vilibald Sluga, he succeeds to the organization and operation of the hospital to an enviable level. Across the Austro-Hungarian Empire and Croatian, Hospitals Red Cross, had a significant role in caring for the wounded, injured and sick soldiers and civilians. Red Cross Hospital in Krapina, is an example of a well-organized hospital in the toughest conditions. Such an organization was not simple in its implementation, and left the valuable lessons and experience.

  5. Understanding the Role of Medical Experts during a Public Health Crisis Digital Tools and Library Resources for Research on the 1918 Spanish Influenza.

    PubMed

    Ewing, E Thomas; Gad, Samah; Ramakrishnan, Naren; Reznick, Jeffrey S

    2014-10-01

    Humanities scholars, particularly historians of health and disease, can benefit from digitized library collections and tools such as topic modeling. Using a case study from the 1918 Spanish Flu epidemic, this paper explores the application of a big humanities approach to understanding the impact of a public health official on the course of the disease and the response of the public, as documented through digitized newspapers and medical periodicals.

  6. The first announcement about the 1918 "Spanish flu" pandemic in Greece through the writings of the pioneer newspaper "Thessalia" almost a century ago.

    PubMed

    Tsoucalas, Gregory; Karachaliou, Fotini; Kalogirou, Vasiliki; Gatos, Giorgos; Mavrogiannaki, Eirini; Antoniou, Antonios; Gatos, Konstantinos

    2015-03-01

    A local pioneer newspaper, "Thessalia", was the first to announce the arrival of "Spanish Flu" in Greece. It was July 19th 1918 when an epidemic outbreak occurred in the city of Patras. Until then, "Thessalia" had dealt in depth with the flu pandemic in the Greek district of Thessaly, informing the readers of the measures taken, as well as the social and economic aspects of the flu.

  7. A geographic analysis of population density thresholds in the influenza pandemic of 1918–19

    PubMed Central

    2013-01-01

    Background Geographic variables play an important role in the study of epidemics. The role of one such variable, population density, in the spread of influenza is controversial. Prior studies have tested for such a role using arbitrary thresholds for population density above or below which places are hypothesized to have higher or lower mortality. The results of such studies are mixed. The objective of this study is to estimate, rather than assume, a threshold level of population density that separates low-density regions from high-density regions on the basis of population loss during an influenza pandemic. We study the case of the influenza pandemic of 1918–19 in India, where over 15 million people died in the short span of less than one year. Methods Using data from six censuses for 199 districts of India (n=1194), the country with the largest number of deaths from the influenza of 1918–19, we use a sample-splitting method embedded within a population growth model that explicitly quantifies population loss from the pandemic to estimate a threshold level of population density that separates low-density districts from high-density districts. Results The results demonstrate a threshold level of population density of 175 people per square mile. A concurrent finding is that districts on the low side of the threshold experienced rates of population loss (3.72%) that were lower than districts on the high side of the threshold (4.69%). Conclusions This paper introduces a useful analytic tool to the health geographic literature. It illustrates an application of the tool to demonstrate that it can be useful for pandemic awareness and preparedness efforts. Specifically, it estimates a level of population density above which policies to socially distance, redistribute or quarantine populations are likely to be more effective than they are for areas with population densities that lie below the threshold. PMID:23425498

  8. Accumulation of CD11b+Gr-1+ cells in the lung, blood and bone marrow of mice infected with highly pathogenic H5N1 and H1N1 influenza viruses

    PubMed Central

    Kotur, Mark S.; Stark, Gregory V.; Warren, Richard L.; Kasoji, Manjula; Craft, Jeremy L.; Albrecht, Randy A.; García-Sastre, Adolfo; Katze, Michael G.; Waters, Katrina M.; Vasconcelos, Daphne; Sabourin, Patrick J.; Bresler, Herbert S.; Sabourin, Carol L.

    2017-01-01

    Infection with pathogenic influenza viruses isassociated with intense inflammatory disease. Here, we investigated the innate immune response in mice infectedwith H5N1 A/Vietnam/1203/04 and with reassortanthuman H1N1 A/Texas/36/91 viruse s containing the virulence genes hemagglutinin (HA), neuraminidase (NA) and NS1 of the 1918 pandemic virus. Inclusion of the 1918 HAand NA glycoproteins rendered a seasonal H1N1 virus capable of inducing an exacerbated host innate immuneresponse similar to that observed for highly pathogenicA/Vietnam/1203/04 virus. Infection with 1918 HA/NA:Tx/91 and A/Vietnam/1203/04 were associated with severelung pathology, increased cytokine and chemokine production, and significant immune cell changes, including the presence of CD11b+Gr-1+cells in the blood, lung and bone marrow. Significant differential gene expression in the lung included pathways for cell death, apoptosis, production and response to reactive oxygen radicals, as well asarginine and proline meta bolism and chemokines associated with monocyte and neutrophil/granulocyte accumulation and/or activation. Arginase was produced in the lungof animals infected with A/Vietnam/1204. These results demonstrate that the innate immune cell response resultsin t he accumulation of CD11b+Gr-1+cells and products that have previously been shown to contribute to T cellsuppression. PMID:23397329

  9. Pioneering Jewish women doctors in Eretz Israel (Ottoman Palestine) 1900-1918.

    PubMed

    Shehory-Rubin, Zipora

    2010-12-01

    The first female Jewish doctors in Eretz Israel at the end of the nineteenth and the beginning of the twentieth centuries were partners in laying the foundations of its health system in Eretz Israel. They were young doctors in their late twenties or even mid-thirties, graduates of European medical schools. Educated, independent women, with high motivation and belief in the future of medicine in the country, they worked unceasingly, with devotion and determination and invested most of their efforts and knowledge in creating medical institutions there, in order that a new generation, sound in mind and body, might flourish. These doctors came with a sense of vocation, viewing medicine as a national, Zionist mission and not merely a source of income. Despite the contribution these first doctors made to the creation of the health system in this country, they remained largely anonymous, while their medical and social involvement has been largely ignored in the historical literature. This paper focuses on twenty-two women who successfully completed their medical studies in European institutions, followed by emigration to Eretz Israel between 1900 and 1918. While the secondary literature mentions these women individually they are not considered as a group.

  10. Managing boundaries between professional and lay nursing following the influenza pandemic, 1918-1919: insights for professional resilience today?

    PubMed

    Wood, Pamela J

    2017-03-01

    To examine lay-professional nursing boundaries, using challenges to the New Zealand nursing profession following the 1918-1919 influenza pandemic as the example. The influenza pandemic of 1918-1919 had an overwhelming international impact on communities and the nursing profession. After the pandemic, the expectation for communities to be able to nurse the sick reflects today's increasing reliance on families to care for people at home. It similarly raised questions about the profession's role and professional boundaries in relation to volunteer or lay nursing. In New Zealand, the postpandemic challenge to build community lay nursing capacity tested these boundaries. Historical research. Analysis of historical primary sources of official reports, newspaper accounts, articles in New Zealand's professional nursing journal Kai Tiaki and the memoir of Hester Maclean, the country's chief nurse. Interpretation of findings in relation to secondary sources examining similar historical tensions between professional and lay nursing, and to the more recent notion of professional resilience. Maclean guarded nursing's professional boundaries by maintaining considerable control over community instruction in nursing and by strenuously resisting the suggestion that this should be done in hospitals where professional nurses trained. This historical example shows how the nursing profession faced the perceived threat to its professional boundaries. It also shows how competing goals of building community lay nursing capacity and protecting professional boundaries can be effectively managed. In the context of a global nursing shortage, limited healthcare budgets and a consequently increasing reliance on households to provide care for family members, this historical research shows nurses today that similar issues have been faced and effectively managed in the past. © 2016 John Wiley & Sons Ltd.

  11. [Reiter disease or reactive arthritis?].

    PubMed

    Eppinger, S; Schmitt, J; Meurer, M

    2006-04-01

    There is an ongoing international discussion on whether the condition reactive arthritis should be named after a former Nazi functionary. The German dermatological community should participate in this debate. In 1916, Hans Reiter described a disease with the symptoms urethritis, conjunctivitis, and arthritis, which was later named after him. After becoming titular professor in May 1918, Reiter was appointed director of the regional public health department Mecklenburg-Schwerin in 1926. At the same time he taught social hygiene at the University of Rostock, where he was appointed full professor in 1928. In 1931, Hans Reiter became a member of the National Socialist German Workers Party (NSDAP). In July 1932 he was elected representative of the NSDAP to the seventh assembly of Mecklenburg-Schwerin. After becoming its acting director in July 1933, Reiter was appointed president of the Reich public health department in Berlin on October 1, 1933. Both his excellent professional qualifications, as well as his National Socialist attitudes, were considered key criteria for taking over this important position. As the president of the Reich public health department, Reiter was said to have known about the conduct of experiments with typhus-fever at the concentration camp Buchenwald in which 250 humans died. From the end of the Second World War until 1947, Reiter was imprisoned in the Nuremberg Prison for War Criminals, but never convicted of a crime.

  12. Family structure and childhood anthropometry in Saint Paul, Minnesota in 1918

    PubMed Central

    Warren, John Robert

    2017-01-01

    Concern with childhood nutrition prompted numerous surveys of children’s growth in the United States after 1870. The Children’s Bureau’s 1918 “Weighing and Measuring Test” measured two million children to produce the first official American growth norms. Individual data for 14,000 children survives from the Saint Paul, Minnesota survey whose stature closely approximated national norms. As well as anthropometry the survey recorded exact ages, street address and full name. These variables allow linkage to the 1920 census to obtain demographic and socioeconomic information. We matched 72% of children to census families creating a sample of nearly 10,000 children. Children in the entire survey (linked set) averaged 0.74 (0.72) standard deviations below modern WHO height-for-age standards, and 0.48 (0.46) standard deviations below modern weight-for-age norms. Sibship size strongly influenced height-for-age, and had weaker influence on weight-for-age. Each additional child six or underreduced height-for-age scores by 0.07 standard deviations (95% CI: −0.03, 0.11). Teenage siblings had little effect on height-forage. Social class effects were substantial. Children of laborers averaged half a standard deviation shorter than children of professionals. Family structure and socio-economic status had compounding impacts on children’s stature. PMID:28943749

  13. To 130-th birthday anniversary of Friedrich Tsander (1887-1933): Ten new Russian books in Astrodynamics as the honorable contribution to his memory

    NASA Astrophysics Data System (ADS)

    Polyakhova, E. N.; Ovchinnikov, M. Yu.; Tikhonov, A. A.

    2018-05-01

    Short bibliographic review of several books on Astrodynamics written in Russian is outlined in frame of the scientific legacy of Friedrich Tsander (1887-1933). He was the outstanding soviet engineer, inventor and scientist who lived in Moscow in 1920s. Our review concerns only ten books edited and published in 2000-2017. We consider these books as the necessary honorable contribution to Tsander's memory to the 130-th Anniversary of his birthday. We outline several sections as follows: New translations to Russian, Textbooks and Educational Issues, Scientific Monograph on Astrodynamics, Electrodynamics and Magnetism in Space, Solar Sailing Dynamics.

  14. Foraging behavior of stingless bee Heterotrigona itama (Cockerell, 1918) (Hymenoptera : Apidae : Meliponini)

    NASA Astrophysics Data System (ADS)

    Jaapar, Mohd Fahimee; Jajuli, Rosliza; Mispan, Muhamad Radzali; Ghani, Idris Abd

    2018-04-01

    A study to investigate the foraging behavior of Heterotrigona itama (Cockerell, 1918) was conducted on three colonies between January 2016 and June 2016. A digital single-lens reflex (DSLR) with macro lens attached, and action camera (SJCAM) was used to record foraging behavior of H. itama in its colonies for 5 min per hour between 0800 to 1700 h for a day per 6 months. In addition, three data loggers (Watchdog B100 2K) has been installed adjacent to the observation nest for collect temperature and humidity in the study areas. Result showed that the numbers of return foragers was significantly different from January to June also with outgoing forager. The returning forager between hours showed significant different from 8 am to 5 pm also for outgoing forager. The ideal temperature related to foraging behavior for H. itama was 29°C to 32 °C Our finding also, helps to guide researcher to expand the knowledge in foraging behavior by stingless bee as well as encouraging more small farmers to start rearing at least for their own consumption. In addition, these findings also guide the farmers to manage their chemical toxic inside the meliponiculture.

  15. [Health and social conditions in Brod na Savi during World War I].

    PubMed

    Jandrić-Balen, Marica; Balen, Ivica

    2015-11-01

    During World War I, social and health conditions were difficult in Brod na Savi, as it stationed a large number of troops, and the military hospital was crowded with patients. With so many able-bodied men and breadwinners mobilised, the town's economy verged on the brink of poverty, but people managed to keep starvation at bay. The most common diseases among civilians were tuberculosis, malaria, intestinal infectious diseases, diphtheria, and venereal diseases, and in 1915 cholera broke out that lasted five months. At the end of 1918 "Spanish flu" also hit the town. The number of wounded and sick soldiers occasionally surpassed the hospital's capacity, so they had to be stationed at the local school facilities for a while. Over two thousand people died in the military hospital, which suggests that the total number of patients who went through the hospital had to be very large. Unfortunately, there are no records to show the hospital's mortality rate or disease prevalence. We are currently trying to establish the demographics of the 2000 dead buried at the local cemetery during WWI using the death records we have.

  16. A new look at an old virus: patterns of mutation accumulation in the human H1N1 influenza virus since 1918

    PubMed Central

    2012-01-01

    Background The H1N1 influenza A virus has been circulating in the human population for over 95 years, first manifesting itself in the pandemic of 1917–1918. Initial mortality was extremely high, but dropped exponentially over time. Influenza viruses have high mutation rates, and H1N1 has undergone significant genetic changes since 1918. The exact nature of H1N1 mutation accumulation over time has not been fully explored. Methods We have made a comprehensive historical analysis of mutational changes within H1N1 by examining over 4100 fully-sequenced H1N1 genomes. This has allowed us to examine the genetic changes arising within H1N1 from 1918 to the present. Results We document multiple extinction events, including the previously known extinction of the human H1N1 lineage in the 1950s, and an apparent second extinction of the human H1N1 lineage in 2009. These extinctions appear to be due to a continuous accumulation of mutations. At the time of its disappearance in 2009, the human H1N1 lineage had accumulated over 1400 point mutations (more than 10% of the genome), including approximately 330 non-synonymous changes (7.4% of all codons). The accumulation of both point mutations and non-synonymous amino acid changes occurred at constant rates (μ = 14.4 and 2.4 new mutations/year, respectively), and mutations accumulated uniformly across the entire influenza genome. We observed a continuous erosion over time of codon-specificity in H1N1, including a shift away from host (human, swine, and bird [duck]) codon preference patterns. Conclusions While there have been numerous adaptations within the H1N1 genome, most of the genetic changes we document here appear to be non-adaptive, and much of the change appears to be degenerative. We suggest H1N1 has been undergoing natural genetic attenuation, and that significant attenuation may even occur during a single pandemic. This process may play a role in natural pandemic cessation and has apparently contributed to the

  17. The possible roles of solar ultraviolet-B radiation and vitamin D in reducing case-fatality rates from the 1918–1919 influenza pandemic in the United States

    PubMed Central

    Giovannucci, Edward

    2009-01-01

    Deaths during the 1918–1919 influenza pandemic have been linked to both the influenza virus and secondary bacterial lung infections. Case fatality rates and percentage of influenza cases complicated by pneumonia were available from survey data for twelve United States locations in the 1918–1919 pandemic. This study analyzes case fatality rates and cases complicated by pneumonia with respect to estimated summertime and wintertime solar ultraviolet-B (UVB) doses as indicators of population mean vitamin D status. Substantial correlations were found for associations of July UVB dose with case fatality rates (r = −0.72, p = 0.009) and rates of pneumonia as a complication of influenza (r = −0.77, p = 0.005). Similar results were found for wintertime UVB. Vitamin D upregulates production of human cathelicidin, LL-37, which has both antimicrobial and antiendotoxin activities. Vitamin D also reduces the production of proinflammatory cytokines, which could also explain some of the benefit of vitamin D since H1N1 infection gives rise to a cytokine storm. The potential role of vitamin D status in reducing secondary bacterial infections and loss of life in pandemic influence requires further evaluation. PMID:20592793

  18. Acquired immunity against malaria as a tool for the control of the disease: the strategy proposed by the Malaria Commission of the League of Nations in 1933.

    PubMed

    Corbellini, G

    1998-06-01

    The Third General Report of the Malaria Commission, printed in 1933, suggested for the control of malaria a strategy aimed to promote the acquisition of a "relative immunity" through a non radical treatment of the infected people living in highly endemic areas. The paper discusses the content of the Report and describes the scientific (empirical) premises on which it stood. Moreover, it illustrates the criticism that was directed against the immunological strategy and that eventually led to its abandonment.

  19. Neurology at Escola Paulista de Medicina (1933-1995). From Fausto Guerner to José Geraldo Camargo Lima.

    PubMed

    Ferraz, Henrique Ballalai; Neves, Afonso Carlos

    2015-02-01

    Escola Paulista de Medicina (EPM) was founded in 1933 and the first Professor of Neurology was Fausto Guerner, who could not effectively assume the teaching activities due to his premature death in 1938. Professor Guerner had had his neurological training at Paris. Professor Longo was his successor. Longo was one of the founders of Arquivos de Neuro-Psiquiatria the foremost journal of neurosciences in Latin American. Longo died in 1967 and Professor Paulo Pupo succeeded him. Pupo introduced electroencephalography in Brazil. After his death in 1970, Professor Dante Giorgi succeeded him until 1974. Professor José Geraldo Camargo Lima took over the position after Giorgi's death. He created the Neurological Emergency unit, initiated the Post-Graduation in Neurology and divided the Discipline in specialized units. During the 1980's and until his retirement in 1995, EPM had become one of most important centers of Brazil training neurologists and researchers in neurological sciences.

  20. Walter Rowe Courtenay, Jr. (1933–2014)

    USGS Publications Warehouse

    Benson, Amy J.

    2016-01-01

    WALTER R. COURTENAY, JR., ichthyologist and retired professor, Florida Atlantic University, Boca Raton, Florida, died in Gainesville, Florida, on 30 January 2014 at age 80. Walt was born in Neenah, Wisconsin, on 6 November 1933, son of Walter and Emily Courtenay. Walt's interest in fish began at a young age as evidenced by a childhood diary in which at 13 years of age he wrote about his first catch—a two-and-a-half pound “pike” from Lake Winnebago. When Walt turned ten, the family moved from Wisconsin to Nashville, Tennessee, the move precipitated by his father accepting a position as pastor of the First Presbyterian Church. During those early days in Nashville, Walt's father would take summers off and travel to Michigan to teach at Camp Miniwanca along the shore of Lake Michigan where father and son honed their angling skills. It was also at that time Walt's father had definite views on what his son should be doing in adult life—in Walt's case it was to become a medical doctor. However, his Woods Hole internship in marine biology and oceanography toward the end of his undergraduate years was a transformative experience for him so much so that he abandoned all ideas of becoming a medical doctor and instead specialized in ichthyology and oceanography. Apart from the inherent interest and opportunities Woods Hole opened to him, being back at the shore of a large body of water, in this case the Atlantic Ocean, was far more interesting than sitting in lectures on organic chemistry. With that, Walt completed his B.A. degree at Vanderbilt University in 1956. In 1960 while in graduate school in Miami, Walt met and married Francine Saporito, and over the next several years had two children, Walter III and Catherine. He went on to receive his M.S. in 1961 from The Rosenstiel School of Marine and Atmospheric Science at the University of Miami on the systematics of the genus Haemulon (grunts) and his Ph.D. degree in 1965 working under his advisor C. Richard

  1. Employers, the government, and industrial fatigue in Britain, 1890-1918.

    PubMed Central

    McIvor, A J

    1987-01-01

    The evolution of the concept of industrial fatigue and the responses of employers and the government in Britain to research initiatives in this field of industrial medicine up to the end of the first world war is explored. The discussion dovetails in with the broader debate about the characteristics and dissemination of scientific labour management in Britain. The first section focuses on attitudes towards human energy expenditure and overwork in the nineteenth century. Following this is a discussion of the shorter hours movement of the 1890s, the important experiment at the Manchester engineering firm of Mather and Platt, and the reaction of British employers and the government to this. Finally, a brief analysis is made of the progress in research into workers' health, fatigue, and efficiency during the 1914-8 war, particularly concentrating on the role of the Health and Munition Workers Committee in pioneering the scientific study of industrial medicine. This led directly to the establishment of the Industrial Fatigue Research Board in 1918. Though there are significant caveats, it is argued that before the first world war a wide gap existed between research findings, best practice, and the common workshop experience and that in general British management (with some notable exceptions) grossly neglected the human element in production, ignored human physiological and psychological limitations, and hence both created and exacerbated serious problems of mental and physical fatigue and overstrain. PMID:3318915

  2. "Co-operation in All Human Endeavour": quarantine and immigrant disease vectors in the 1918-1919 influenza pandemic in Winnipeg.

    PubMed

    Jones, Esyllt W

    2005-01-01

    Unlike occurrences of other contagious diseases such as cholera and smallpox, the 1918-19 influenza pandemic did not lead to anti-immigrant backlash, the stigmatization of newcomers as disease carriers, or aggressive quarantine measures focused against immigrant groups. During influenza outbreaks in several major Canadian cities, quarantine was either rejected or was a low-priority containment measure, reluctantly and sceptically employed. Blaming immigrants during the epidemic was not considered enlightened public health practice or good disease containment strategy. Retrospective evaluation of the successes and failures of the fight against influenza concluded that coercive measures such as quarantine did more harm than good. The experience with influenza contributed to new notions of immigrant inclusion in the social body.

  3. [Identity and social integration: analysis of sociability in a mutual aid society (1902-1933)].

    PubMed

    León Sanz, Pilar

    2015-01-01

    This article studies the sociability evidenced in the fiestas and other celebrations held by the Breastfeeding Infant Clinic and periodically organized by La Conciliación Mutual Aid Society between 1902 and 1933 as recreational acts with educational purposes. La Conciliación (1902-1984) was founded in Pamplona as an exclusively male Catholic association (women were admitted from 1936) composed of workers, employers and protector members, with labor, healthcare, and economic objectives under a Mixed Board of Governors with representatives from the three cohorts. The description of the events and the analyses of the emotional practices are based on newspaper reports and the association's archives. The acts organized by the Breastfeeding Infant Clinic served to stimulate positive emotions and maternal feelings of piety and charity and to arouse a sense of social utility in the upper social classes. We acknowledge the regulatory component of the emotions that appeared in the fiesta of La Conciliatión: conferences and social events proposed a social model that reinforced the participation of members and their families in the association's ideological and religious goals. The performative character of emotions was designed to reinforce the identity of the members of La Conciliation and their social integration in the city. This model of sociability strengthened the project of La Conciliation.

  4. The hydrogeology of the military inundation at the 1914-1918 Yser front (Belgium)

    NASA Astrophysics Data System (ADS)

    Vandenbohede, Alexander

    2016-03-01

    Protection against flooding by the sea, drainage of rainwater and integrated management of groundwater and surface-water resources are key issues in low-lying coastal areas. However, under exceptional circumstances, knowledge to keep coastal areas dry and habitable can be used otherwise. Inundation for military purposes is such an example. The hydrogeology of the inundation at the Yser River, Belgium, during the Great War is studied. The inundation started in October 1914 to stop the German advance and lasted until 1918. A water balance and groundwater model are combined to derive the water balance before and during the inundation and to study the impact on the groundwater system. It is concluded that a number of hydrogeological factors contributed to the effectiveness of the inundation. Most importantly, the low-permeability subsoil facilitated loss of inundation water mainly by evaporation. Further, the normal water management strategy of the area (aimed at evacuating excess water towards the sea) was reversed to keep water between the opposing armies. However, the duration of the inundation meant a reorganization of the drainage of areas not inundated; truly an exercise in integrated water management.

  5. Child health in the workplace: the Supreme Court in Hammer v. Dagenhart (1918).

    PubMed

    Berger, L R; Johansson, S R

    1980-01-01

    Exploitation of children in the labor force at the beginning of this century gave rise to a national campaign leading to congressional passage of the Keating-Owen Act in 1916. The act prohibited from interstate commerce goods produced in factories or mines that employed children who either were under fourteen years of age or who were under sixteen years of age and worked more than eight hours a day. Despite its popular support, the Act was declared unconstitutional by the Supreme Court in Hammer v. Dagenhart (1918). The Court's decision involved several major issues: interpretation of the Fifth and Fourteenth Amendments to the Constitution, freedom of contract, police power of the states, and the interstate commerce clause. Review of previous Court decisions suggests that the justices were on less than solid legal ground in reaching their decision. Examination of the historical context of the decision, however, suggests other factors that may have played a more important role than judicial precedents. The debate prompted by Hammer v. Dagenhart has much relevance to such current issues as young agricultural workers, sex discrimination in industry, and the powers of the federal government vis-a-vis states and individual citizens.

  6. Encephalitis lethargica and the influenza virus. II. The influenza pandemic of 1918/19 and encephalitis lethargica: epidemiology and symptoms*

    PubMed Central

    Foley, Paul Bernard

    2009-01-01

    This is the first of two papers which critically examine the relationship between the 1918/19 influenza pandemic and encephalitis lethargica (EL). The role of influenza in the etiology of EL was vigorously debated until 1924. It is notable, however, that the unitarian camp were largely reactive in their argumentation; while the influenza skeptics provided detail descriptions of EL and the features they argued to be unique or at least unusual, influenza supporters focused on sequentially refuting the evidence of their opponents. The impression which emerges from this debate is that the individual features identified by the skeptics were not absolutely pathognomic for EL, but, on the other hand, their combination in one disorder had not previously been described for any other disease. PMID:19707848

  7. Encephalitis lethargica and the influenza virus. III. The influenza pandemic of 1918/19 and encephalitis lethargica: neuropathology and discussion*

    PubMed Central

    Foley, Paul Bernard

    2009-01-01

    This is the second of two papers which critically examine the relationship between the 1918/19 influenza pandemic and encephalitis lethargica (EL). The role of influenza in the etiology of EL was vigorously debated until 1924. It is notable, however, that the unitarian camp were largely reactive in their argumentation; while the influenza skeptics provided detail descriptions of EL and the features they argued to be unique or at least unusual, influenza supporters focused on sequentially refuting the evidence of their opponents. The impression which emerges from this debate is that the individual features identified by the skeptics were not absolutely pathognomic for EL, but, on the other hand, their combination in one disorder had not previously been described for any other disease. PMID:19707847

  8. Marasti Village, 1918-1924 … A Neo-Romanian Experiment

    NASA Astrophysics Data System (ADS)

    Idiceanu-Mathe, Dan; Carjan, Roxana

    2017-10-01

    Mărăști Village, 1918, a village on the front line of the First World War, the place where General Mackensen and General Averescu met face to face for 12 days. After the 12 days of heavy fighting at an altitude of 536 meters, the Romanians won the battle, but they lost 4800 people and the village was destroyed. The village was rehabilitated due to Mărăști Society; whose objective was to rebuild it as a “historical village in the Romanian style”. The place was in a building site for 6 years. A number of 73 houses were rehabilitated and 20 new houses, a church and a school were erected. The village was provided with a water supply system and an electricity grid with diesel-generators. All this was designed in the Neo-Romanian style by 6 architects. In a short period and on a large territory, the terrible consequences of the war were changed into a reconstruction and modernization theme, from the infrastructure in general to the dwellings in particular. It was a tremendous effort because of the isolated position of the village, which required an impressive logistic support for those times. The new architectural products were designed in the style that was already considered the Neo-Romania style in the 1910-1920 decade. The village is important because it was modernized from the urban point of view. It was a completely new manner characteristic of the urban development in an area where the last Middle Ages peasant upheaval took place in 1907. In the Romanian context, the execution is unique in dimension, scale and theme. At the International level, it is considered a very precise and rare architectural intervention.

  9. Selective Bottlenecks Shape Evolutionary Pathways Taken during Mammalian Adaptation of a 1918-like Avian Influenza Virus.

    PubMed

    Moncla, Louise H; Zhong, Gongxun; Nelson, Chase W; Dinis, Jorge M; Mutschler, James; Hughes, Austin L; Watanabe, Tokiko; Kawaoka, Yoshihiro; Friedrich, Thomas C

    2016-02-10

    Avian influenza virus reassortants resembling the 1918 human pandemic virus can become transmissible among mammals by acquiring mutations in hemagglutinin (HA) and polymerase. Using the ferret model, we trace the evolutionary pathway by which an avian-like virus evolves the capacity for mammalian replication and airborne transmission. During initial infection, within-host HA diversity increased drastically. Then, airborne transmission fixed two polymerase mutations that do not confer a detectable replication advantage. In later transmissions, selection fixed advantageous HA1 variants. Transmission initially involved a "loose" bottleneck, which became strongly selective after additional HA mutations emerged. The stringency and evolutionary forces governing between-host bottlenecks may therefore change throughout host adaptation. Mutations occurred in multiple combinations in transmitted viruses, suggesting that mammalian transmissibility can evolve through multiple genetic pathways despite phenotypic constraints. Our data provide a glimpse into avian influenza virus adaptation in mammals, with broad implications for surveillance on potentially zoonotic viruses. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Women in-between' (Strathern, 1995): the ambiguous position of the sister tutor, 1918-1960.

    PubMed

    Brooks, Jane

    2007-02-01

    The purpose of this article is to explore the ambiguous position of sister tutors, within the nursing and hospital hierarchy between 1918 and 1960. The function of the sister tutor was to train the probationers (student nurses). However, I will argue that the students' education was to come second to the service needs of the hospital, the authority of the matron and desire of the medical profession to maintain control over the nursing curriculum and nursing practice. Therefore sister tutors were caught 'in-between' several opposing forces which together militated against the individual sister tutor's work and the ability of the nursing profession to recruit adequate numbers of senior nurses into the classroom. The recruitment issue was further hampered by the widespread knowledge that much of the sister tutor's work was not student education at all, but organising lectures by medical staff and marking students' notes. In order to gauge the 'official' attitudes to the sister tutors and also the experiences of those who either worked as sister tutors or were taught by them, I used both archival and oral evidence in the research for this article. Pseudonyms have been used throughout for the oral history respondents.

  11. Life story of Dr. Hulusi Behçet.

    PubMed

    Saylan, T

    1997-12-01

    Dr. Hulusi Behçet was born on February 20, 1889 in Istanbul. He graduated from Gülhane Military Medical Academy in 1910 and then he specialized in Dermatology and Venereal Diseases. He served in the Edirne Military Hospital between 1914-1918 and then went to Budapest and Berlin to improve his knowledge. In 1923, he started at the Istanbul Medical Faculty as an academic staff and with university reform in 1933, he was appointed as a professor to Department of Dermatology and Venereal Diseases and continued his career there until his death in 1948. Three patients whom he had consulted for years and who shared similar symptoms made him suspect a new disease and a viral etiology which may play a role in the appearance of this disease. After several discussions and publications, medical literature had accepted Behçet's Disease as a special entity. Dr. Behçet published a total of 196 articles, 53 of which were published in prestigious international journals.

  12. [Paul Konitzer (1894-1947): hygienist, physician, social medicine and health politician].

    PubMed

    Schneck, Peter

    2004-01-01

    Paul Konitzer was one of the outstanding and well-known physicians in the years after the World War II in East-Germany. THe paper describes his professional way as hygienist, social medical, municipal physician and last but not least as health politician in the times of four different political regimes: the imperial era in Germany till 1918, the time of "Weimarer Republic" till 1933, the Nazi dictatorship till 1945 and the early years in the Soviet occupation zone of Germany. The life of Konitzer is a typical example of the fate of a German doctor in the first half of the 20th century. Konitzer was arrested in February 1947 by the Soviet Military Government in Berlin in connection with some political troubles and reproach with a typhus epidemic in a German camp for Russian Prisoners of War in the Nazi era. On April 22nd 1947 he died in prison of Dresden by suicide without condemnation.

  13. Sir Edward Mellanby (1884-1955) GBE KCB FRCP FRS: nutrition scientist and medical research mandarin.

    PubMed

    Hawgood, Barbara J

    2010-08-01

    Edward Mellanby used the experimental method to investigate medical problems. In 1918, working at King's College for Women, London, he provided conclusive evidence that rickets is a dietary deficiency disease due to lack of a fat-soluble vitamin [D]. In Sheffield he demonstrated that cereals, in an unbalanced diet, produced rickets due to the phytic acid content reducing the availability of calcium. Mellanby became Secretary of the Medical Research Council (1933-49) but continued his research by working at weekends. In the 1930s he campaigned for the results of nutritional research to be used for the benefit of public health. During World War II he acted as a scientific adviser to the War Cabinet and had a strong influence on the food policy which maintained successfully the nutrition of the population during the shipping blockade. Mellanby was a formidable person but with sagacity he promoted new research and guided the expansion of the organization.

  14. Regulating the 1918-19 pandemic: flu, stoicism and the Northcliffe press.

    PubMed

    Honigsbaum, Mark

    2013-04-01

    Social historians have argued that the reason the 1918–19 ‘Spanish’ influenza left so few traces in public memory is that it was ‘overshadowed’ by the First World War, hence its historiographical characterisation as the ‘forgotten’ pandemic. This paper argues that such an approach tends to overlook the crucial role played by wartime propaganda. Instead, I put emotion words, emotives and metaphors at the heart of my analysis in an attempt to understand the interplay between propaganda and biopolitical discourses that aimed to regulate civilian responses to the pandemic. Drawing on the letters of Wilfred Owen, the diaries of the cultural historian Caroline Playne and the reporting in the Northcliffe press, I argue that the stoicism exhibited by Owen and amplified in the columns of The Times and the Daily Mail is best viewed as a performance, an emotional style that reflected the politicisation of ‘dread’ in war as an emotion with the potential to undermine civilian morale. This was especially the case during the final year of the conflict when war-weariness set in, leading to the stricter policing of negative emotions. As a protean disease that could present as alternately benign and plague-like, the Spanish flu both drew on these discourses and subverted them, disrupting medical efforts to use the dread of foreign pathogens as an instrument of biopower. The result was that, as dread increasingly became attached to influenza, it destabilised medical attempts to regulate the civilian response to the pandemic, undermining Owen’s and the Northcliffe press’s emotives of stoicism.

  15. Fighting flu: military pathology, vaccines, and the conflicted identity of the 1918-19 pandemic in Britain.

    PubMed

    Bresalier, Michael

    2013-01-01

    This article explores the decisive role of British military medicine in shaping official approaches to the 1918 influenza pandemic. It contends that British approaches were defined through a system of military pathology, which had been established by the War Office as part of the mobilization of medicine for the First World War. Relying on the bacteriological laboratory for the identification and control of pathogenic agents, military pathology delivered therapeutic and preventive measures against a range of battlefield diseases, and military and civilian authorities trusted that it could do the same with influenza. This article traces how it shaped efforts to establish the etiology of the pandemic and to produce a general influenza vaccine. It highlights the challenges involved in both strategies. Understanding the central role of military pathology helps make sense of the nature, direction, scale, and limitations of medical mobilization against the pandemic in Britain and the authority accorded to specific medical bodies for elaborating and coordinating strategies. Crucially, it demands that we rethink the relationship between the war and pandemic as one about the social organization of medical knowledge and institutions.

  16. [Epidemiological situation of the selected infectious diseases in Poland in 1918-1939].

    PubMed

    Sztuka-Polińska, Urszula

    2002-01-01

    In Poland, during twenty years between the first and the second world war modern methods and remedies were created and applied to save the society from biological extermination caused by the epidemics of acute infectious diseases that existed in the larger areas of the country and other diseases that could threaten the society when brought from abroad. Poland regained its independence in 1918 as a country completely destroyed by war and encompassed three partitioned sectors that differed in wealth, class consciousness, various infrastructure, legislation, epidemiological situation of infectious diseases and threats spreading from abroad. Infectious diseases such as typhus fever, typhoid fever, cholera, smallpox, dysentery and other diseases spreading by alimentary tracts caused the greatest epidemiological problem. The considerable number of smallpox cases was noted in 1920-1922. In the thirties only individual cases occurred. Since 1934 no fatal cases of smallpox were registered. In 1919, in Poland 219,688 cases and 18,641 typhus fever deaths were registered. Between 1930 and 1939 the annual number of cases ranged from 2000 to 4000. In Poland each year between the first and the second world war typhoid fever was a serious sanitary problem. The largest outbreak of dysentery occurred in Poland in 1920-1921 and comprised 64,000 cases, among them 10,000 deaths. Acute childhood diseases such as scarlet fever and diphtheria were in Poland endemic. Number of registered cases was variable.

  17. The Evolution of the American Journal of Psychology, 1904-1918: A Network Investigation.

    PubMed

    Green, Christopher D; Feinerer, Ingo

    2016-01-01

    In an earlier article, we used digital historical methods to examine the first 14 volumes (1887-1903) of The American Journal of Psychology (AJP) by creating networks of the vocabularies used in every substantive article the journal published in those years. These networks showed us the major research groups that had been gathered together by the journal's founder-editor, G. Stanley Hall, and how the intellectual composition of the journal (and the discipline) changed over that 17-year period. In the present article we extended that study forward, creating networks for the next 15 volumes (1904-1918), broken into time blocks of 5 years each. Our findings, in brief, were that vision research (especially color) continued to play as consistent and prominent role in the journal as it had since the start; that memory, association, and some higher mental processes were active areas of research throughout; that Hall continued to have an on-again, off-again relationship with theoretical and philosophical psychology; that intelligence-measuring methods, psychoanalysis, and psychophysics were periodically popular enough that they each generated a cluster in 1 of the 3 time blocks; and that Titchener's participation in the editing of AJP led to its becoming the major outlet for his Structuralist research program (an absence that we noted in our earlier studies of the journal Psychological Review).

  18. From the Air: Rediscovering Our Raison D’etre

    DTIC Science & Technology

    2012-08-01

    constraints and war weariness take their toll . Ensuring that the Air Force can serve the na- tion in its capacity as a strategic arm represents a... Lawson   and Jane Lawson , The First Air Campaign, August 1914–November 1918 (Conshohocken, PA:  Combined Books, 1996); and John H. Morrow Jr., The

  19. Redescription of Mehdiella microstoma and description of Mehdiella petterae sp. n., with a new definition of the genus Mehdiella Seurat, 1918 (Nematoda: Pharyngodonidae).

    PubMed

    Bouamer, S; Morand, S; Bourgat, R

    2001-01-01

    The generic diagnosis of Mehdiella Seurat, 1918 is emended based on study and redescription of Mehdiella microstoma (Drasche, 1884) from the caecum of Testudo graeca Linnaeus, 1758 collected in Settat, Morocco and on study and description of a new species, Mehdiella petterae sp. n., from the large intestine of Testudo hermanni (Gmelin, 1789) collected in Catalonia, Spain. Scanning electron microscopy (SEM) studies revealed substantial differences in the structure of the mouth and the caudal end, and made possible to differentiate the new species from the others. SEM studies showed the real and sound characteristics of the genus Mehdiella, namely number of anal papillae 2 instead of 3, post-anal papillae pedunculate or sessile instead sessile.

  20. Living in "survival mode:" Intergenerational transmission of trauma from the Holodomor genocide of 1932-1933 in Ukraine.

    PubMed

    Bezo, Brent; Maggi, Stefania

    2015-06-01

    Qualitative methodology was used to investigate the intergenerational impact of the 1932-1933 Holodomor genocide on three generations in 15 Ukrainian families. Each family, residing in Ukraine, consisted of a first generation survivor, a second generation adult child and a third generation adult grandchild of the same line. The findings show that the Holodomor, a genocide that claimed millions of lives by forced starvation, still exerts substantial effects on generations born decades later. Specifically, thematic analysis of the 45 semi-structured, in-depth interviews, done between July and November 2010, revealed that a constellation of emotions, inner states and trauma-based coping strategies emerged in the survivors during the genocide period and were subsequently transmitted into the second and third generations. This constellation, summarized by participants as living in "survival mode," included horror, fear, mistrust, sadness, shame, anger, stress and anxiety, decreased self-worth, stockpiling of food, reverence for food, overemphasis on food and overeating, inability to discard unneeded items, an indifference toward others, social hostility and risky health behaviours. Since both the family and community-society were found to be involved in trauma transmission, the findings highlight the importance of multi-framework approaches for studying and healing collective trauma. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Influenza Pandemics and Tuberculosis Mortality in 1889 and 1918: Analysis of Historical Data from Switzerland.

    PubMed

    Zürcher, Kathrin; Zwahlen, Marcel; Ballif, Marie; Rieder, Hans L; Egger, Matthias; Fenner, Lukas

    2016-01-01

    Tuberculosis (TB) mortality declined in the northern hemisphere over the last 200 years, but peaked during the Russian (1889) and the Spanish (1918) influenza pandemics. We studied the impact of these two pandemics on TB mortality. We retrieved historic data from mortality registers for the city of Bern and countrywide for Switzerland. We used Poisson regression models to quantify the excess pulmonary TB (PTB) mortality attributable to influenza. Yearly PTB mortality rates increased during both influenza pandemics. Monthly influenza and PTB mortality rates peaked during winter and early spring. In Bern, for an increase of 100 influenza deaths (per 100,000 population) monthly PTB mortality rates increased by a factor of 1.5 (95%Cl 1.4-1.6, p<0.001) during the Russian, and 3.6 (95%Cl 0.7-18.0, p = 0.13) during the Spanish pandemic. Nationally, the factor was 2.0 (95%Cl 1.8-2.2, p<0.001) and 1.5 (95%Cl 1.1-1.9, p = 0.004), respectively. We did not observe any excess cancer or extrapulmonary TB mortality (as a negative control) during the influenza pandemics. We demonstrate excess PTB mortality during historic influenza pandemics in Switzerland, which supports a role for influenza vaccination in PTB patients in high TB incidence countries.

  2. Patterns in mortality among people with severe mental disorders across birth cohorts: a register-based study of Denmark and Finland in 1982-2006.

    PubMed

    Gissler, Mika; Laursen, Thomas Munk; Ösby, Urban; Nordentoft, Merete; Wahlbeck, Kristian

    2013-09-11

    Mortality among patients with mental disorders is higher than in general population. By using national longitudinal registers, we studied mortality changes and excess mortality across birth cohorts among people with severe mental disorders in Denmark and Finland. A cohort of all patients admitted with a psychiatric disorder in 1982-2006 was followed until death or 31 December 2006. Total mortality rates were calculated for five-year birth cohorts from 1918-1922 until 1983-1987 for people with mental disorder and compared to the mortality rates among the general population. Mortality among patients with severe mental disorders declined, but patients with mental disorders had a higher mortality than general population in all birth cohorts in both countries. We observed two exceptions to the declining mortality differences. First, the excess mortality stagnated among Finnish men born in 1963-1987, and remained five to six times higher than at ages 15-24 years in general. Second, the excess mortality stagnated for Danish and Finnish women born in 1933-1957, and remained six-fold in Denmark and Finland at ages 45-49 years and seven-fold in Denmark at ages 40-44 years compared to general population. The mortality gap between people with severe mental disorders and the general population decreased, but there was no improvement for young Finnish men with mental disorders. The Finnish recession in the early 1990s may have adversely affected mortality of adolescent and young adult men with mental disorders. Among women born 1933-1957, the lack of improvement may reflect adverse effects of the era of extensive hospitalisation of people with mental disorders in both countries.

  3. Hydrologic data for water years 1933-97 used in the River and Reservoir Operations Model, Truckee River basin, California and Nevada

    USGS Publications Warehouse

    Berris, Steven N.; Hess, Glen W.; Bohman, Larry R.

    2000-01-01

    Title II of Public Law 101-618, the Truckee?Carson?Pyramid Lake Water Rights Settlement Act of 1990, provides direction, authority, and a mechanism for resolving conflicts over water rights in the Truckee and Carson River Basins. The Truckee Carson Program of the U.S. Geological Survey, to support implementation of Public Law 101-618, has developed an operations model to simulate lake/reservoir and river operations for the Truckee River Basin including diversion of Truckee River water to the Truckee Canal for transport to the Carson River Basin. Several types of hydrologic data, formatted in a chronological order with a daily time interval called 'time series,' are described in this report. Time series from water years 1933 to 1997 can be used to run the operations model. Auxiliary hydrologic data not currently used by the model are also described. The time series of hydrologic data consist of flow, lake/reservoir elevation and storage, precipitation, evaporation, evapotranspiration, municipal and industrial (M&I) demand, and streamflow and lake/reservoir level forecast data.

  4. Comparable Analysis of the Distribution Functions of Runup Heights of the 1896, 1933 and 2011 Japanese Tsunamis in the Sanriku Area

    NASA Astrophysics Data System (ADS)

    Choi, B. H.; Min, B. I.; Yoshinobu, T.; Kim, K. O.; Pelinovsky, E.

    2012-04-01

    Data from a field survey of the 2011 tsunami in the Sanriku area of Japan is presented and used to plot the distribution function of runup heights along the coast. It is shown that the distribution function can be approximated using a theoretical log-normal curve [Choi et al, 2002]. The characteristics of the distribution functions derived from the runup-heights data obtained during the 2011 event are compared with data from two previous gigantic tsunamis (1896 and 1933) that occurred in almost the same region. The number of observations during the last tsunami is very large (more than 5,247), which provides an opportunity to revise the conception of the distribution of tsunami wave heights and the relationship between statistical characteristics and number of observations suggested by Kajiura [1983]. The distribution function of the 2011 event demonstrates the sensitivity to the number of observation points (many of them cannot be considered independent measurements) and can be used to determine the characteristic scale of the coast, which corresponds to the statistical independence of observed wave heights.

  5. [German ophthalmologists and NSDAP

    PubMed

    Rohrbach, Jens Martin

    2008-01-01

    Approximately 40-45 % of all German physicians joined the National Socialist German Workers Party (NSDAP) until 1945. Reasons for party membership are manifold and still a matter of debate. Very likely, the extraordinary high representation of medical doctors in the NSDAP was rather a result of active entry than recruitment by the party. There are only few data concerning the willingness of ophthalmologists to become a party member ("Parteigenosse", "Pg"). According to the list of University teachers in Germany ("Hochschullehrerkarte"; Federal Archive, Berlin), the list of the members of the German Ophthalmological Society (DOG) of 1934 and especially the list of NSDAP-members (Federal Archive, Berlin) the following conclusions can be drawn: 1. Directors of German University eye hospitals (chairmen) were members of the NSDAP with a frequency of 23% in 1933 and 48% in 1938 as well as in 1943. The motivation for joining the party was most likely the perspective of acceleration of the academic career. 2. "Only" 30% of the ophthalmologists working in private praxis were "Pg" (until 1945). 3. Both chairmen and ophthalmologists in private praxis were equally hindered to join the NSDAP between May 1st 1933 and May 1st 1937 when the party temporarily stopped registration. 4. The majority of ophthalmologists who joined the NSDAP were born between 1880 and 1900 and thus had taken part in World War I as soldiers or had experienced the times of need after WW I. Only few ophthalmologists succeeded in the NS-hierarchy and probably only one ophthalmologist, Walther Löhlein from Berlin, came in personal contact with Adolf Hitler who was constantly in fear for his sight after his eye injury in October 1918. The "Law for the prevention of genetically disabled offsprings" ("Gesetz zur Verhütung erbkranken Nachwuchses") from July 14th, 1933 separated ophthalmologists into two parties: those advocating sterilization to a high degree and those recommending sterilization only

  6. Influenza Pandemics and Tuberculosis Mortality in 1889 and 1918: Analysis of Historical Data from Switzerland

    PubMed Central

    Zürcher, Kathrin; Zwahlen, Marcel; Ballif, Marie; Rieder, Hans L.; Egger, Matthias

    2016-01-01

    Background Tuberculosis (TB) mortality declined in the northern hemisphere over the last 200 years, but peaked during the Russian (1889) and the Spanish (1918) influenza pandemics. We studied the impact of these two pandemics on TB mortality. Methods We retrieved historic data from mortality registers for the city of Bern and countrywide for Switzerland. We used Poisson regression models to quantify the excess pulmonary TB (PTB) mortality attributable to influenza. Results Yearly PTB mortality rates increased during both influenza pandemics. Monthly influenza and PTB mortality rates peaked during winter and early spring. In Bern, for an increase of 100 influenza deaths (per 100,000 population) monthly PTB mortality rates increased by a factor of 1.5 (95%Cl 1.4–1.6, p<0.001) during the Russian, and 3.6 (95%Cl 0.7–18.0, p = 0.13) during the Spanish pandemic. Nationally, the factor was 2.0 (95%Cl 1.8–2.2, p<0.001) and 1.5 (95%Cl 1.1–1.9, p = 0.004), respectively. We did not observe any excess cancer or extrapulmonary TB mortality (as a negative control) during the influenza pandemics. Conclusions We demonstrate excess PTB mortality during historic influenza pandemics in Switzerland, which supports a role for influenza vaccination in PTB patients in high TB incidence countries. PMID:27706149

  7. [Lifetime achievements of Milan H. Djordjević. 1933-1993].

    PubMed

    Pavlović, Sinisa U

    2002-09-01

    Professor Dr. Sci. Milan Djordjevitsh was an excellent cardiovascular surgeon and results of his professional and research work were well known to professional public in the country and over the world. He was born in Smederevska Palanka in 1933. He finished the University Schfool of Medicine in Belgrade in 1961 and specialized general surgery at the II Department of Surgery in Belgrade. His teacher, prof. dr. Vojislav Stojanovitsh, recognized his special interest for clinical and research work from the beginning. His doctor's thesis (1976) was "The Role of Veinous Valvula in Aortocoronographic Bypass During Increased Coronary Flow". In 1981 he formed a Bypass Centre of the Republic of Serbia which became later the Yugoslav European Reference Centre for pacemaker therapy. The same year (1981) he was rewarded "The October Award of the City of Belgrade" for science. He was the first to implant an implantable cardioverter defibrillator. This technique was carried out in Serbia only two months after the implantation of a similar system in Europe. Professor Djordjevitsh gave many lectures over the world: Detroit (1975), Huston (1975), Budapest (1978), Warsaw (1980), Stockholm (1982), Aman (1984), New-York (1988), Berlin (1987), Vienna (1998), Stockholm (1989), Moscow (1990). The professional and research work of professor Djordjevitsh in the field of electrostimulation of the heart was characterised by original ideas and permanent search for new possibilities, especially in the multidisciplinary field. Therefore, professor Djordjevitsh is considered to be the founder of modern clinical pacemaker therapy. He also practiced artistic and scientific photography. Since 1984 professor Djordjevitsh was member of the Nucleus of the European working group for heart electrostimulation and electrophysiology, and was elected in the presidency of the Nucleus; later he was its president. His interest was directed to the maturation of endocardial stimulation threshold; use of non

  8. A new concept of the epidemic process of influenza A virus.

    PubMed Central

    Hope-Simpson, R. E.; Golubev, D. B.

    1987-01-01

    Influenza A virus was discovered in 1933, and since then four major variants have caused all the epidemics of human influenza A. Each had an era of solo world prevalence until 1977 as follows: H0N1 (old style) strains until 1946, H1N1 (old style) strains until 1957, H2N2 strains until 1968, then H3N2 strains, which were joined in 1977 by a renewed prevalence of H1N1 (old style) strains. Serological studies show that H2N2 strains probably had had a previous era of world prevalence during the last quarter of the nineteenth century, and had then been replaced by H3N2 strains from about 1900 to 1918. From about 1907 the H3N2 strains had been joined, as now, by H1N1 (old style) strains until both had been replaced in 1918 by a fifth major variant closely related to swine influenza virus A/Hswine1N1 (old style), which had then had an era of solo world prevalence in mankind until about 1929, when it had been replaced by the H0N1 strains that were first isolated in 1933. Eras of prevalence of a major variant have usually been initiated by a severe pandemic followed at intervals of a year or two by successive epidemics in each of which the nature of the virus is usually a little changed (antigenic drift), but not enough to permit frequent recurrent infections during the same era. Changes of major variant (antigenic shift) are large enough to permit reinfection. At both major and minor changes the strains of the previous variant tend to disappear and to be replaced within a single season, worldwide in the case of a major variant, or in the area of prevalence of a previous minor variant. Pandemics, epidemics and antigenic variations all occur seasonally, and influenza and its viruses virtually disappear from the population of any locality between epidemics, an interval of many consecutive months. A global view, however, shows influenza continually present in the world population, progressing each year south and then north, thus crossing the equator twice yearly around the

  9. Obituary: William Gordon (1918-2010)

    NASA Astrophysics Data System (ADS)

    Terzian, Yervant

    2011-12-01

    Bill Gordon was born in Paterson, New Jersey on January 8, 1918, and died in Ithaca, New York, on February 16, 2010. He is known as the engineer and ionospheric physicist who conceived and built the Arecibo giant radar/radio telescope. Bill graduated from Montclair State College in New Jersey and then in 1953 received his doctorate degree from Cornell University in electrical engineering, working under Henry Booker. During World War II he was in the Army where he studied the atmospheric conditions that affected radar transmissions. In the mid 1950s he began investigating giant antennas capable of studying the earths ionosphere. He succeeded in raising funds from the US Defense Department to construct the 1000 ft in diameter radar/radio telescope near the city of Arecibo on the island of Puerto Rico. The telescope was completed in 1963 under Bill's management, and he was its first Director. The huge fixed spherical antenna surface was made of a thin wire mesh allowing it to operate at frequencies up to about 600 MHz (50 cm wavelength). The spherical surface required complex 'line feeds' to correct for the spherical aberration, but allowed the telescope to track celestial radio sources by moving the line feeds which were supported by a platform suspended 500 ft above the reflector surface. Its sky coverage declination range was from -2 to +38 degrees. The large collecting area of the telescope made possible the detailed study of the physical properties of the earth's ionosphere. Measurements also included the rotation rates of the planets Mercury and Venus, radar imaging of the Moon and terrestrial planets. This new magastructure operated at low frequencies with its prime frequency at 430 MHz. One of Bill's passions was to make controlled experiments with the ionosphere. These so called 'heating experiments,' used a powerful HF radar transmitting from 5 to 10 MHz, to heat the ionosphere near the plasma frequency. The Arecibo radar then would study the heated

  10. MABAHISS/John Murray 50th Anniversary: Marine Science of the North West Indian Ocean and Adjacent Waters. Report of a Symposium on the Occasion of the 50th Anniversary of the MABAHISS/John Murray Expedition (1933/34) (Alexandria, Egypt, September 3-7, 1983). Unesco Reports in Marine Science, No. 31.

    ERIC Educational Resources Information Center

    United Nations Educational, Scientific, and Cultural Organization, Paris (France). Div. of Marine Sciences.

    An international symposium was convened to celebrate the 50th anniversary of the John Murray Expedition to the Indian Ocean on board the Egyptian research vessel Mabahiss (1933-1934). This report describes the symposium and provides abstracts and syntheses of the papers presented in the various marine scientific disciplines covering the areas of…

  11. Growth of binary organic NLO crystals: m.NA-p.NA and m.NA-CNA system

    NASA Technical Reports Server (NTRS)

    Singh, N. B.; Henningsen, T.; Hopkins, R. H.; Mazelsky, R.

    1993-01-01

    Experiments were carried out to grow 3.Nitroaniline (m.NA) crystals doped with 4.Nitroaniline (p.NA) and 2.chloro 4.Nitroaniline (CNA). The measured undercooling for m.NA, p.NA, and CNA were 0.21 tm K, 0.23 tm K, and 0.35 tm K respectively, where tm represents the melting temperature of the pure component. Because of the crystals' large heat of fusion and large undercooling, it was not possible to grow good quality crystals with low thermal gradients. In the conventional two-zone Bridgman furnace we had to raise the temperature of the hot zone above the decomposition temperature of CNA, p.NA, and m.NA to achieve the desired thermal gradient. To avoid decomposition, we used an unconventional Bridgman furnace. Two immiscible liquids, silicone oil and ethylene glycol, were used to build a special two-zone Bridgman furnace. A temperature gradient of 18 K/cm was achieved without exceeding the decomposition temperature of the crystal. The binary crystals, m.NA-p.NA and m.NA-CNA, were grown in centimeter size in this furnace. X-ray and optical characterization showed good optical quality.

  12. Obituary: Frank J. Low (1933-2009)

    NASA Astrophysics Data System (ADS)

    McCarthy, Don

    2011-12-01

    Frank James Low was born on November 23, 1933, in Mobile, Alabama. He received his undergraduate degree in physics from Yale University in 1955, and his Ph.D. in physics from Rice University in 1959. He worked at Texas Instruments, NRAO, Rice University, and spent most of his career at The University of Arizona with Steward Observatory and the Lunar and Planetary Laboratory. To honor his fundamental insight and innovations that revolutionized the fields of infrared and airborne astronomy, Frank received the Helen B. Warner Prize (1968), the Joseph Weber Award (2003), shared the Rumford Prize in physics (1986), the Karl Jansky Lectureship (2006), and the Bruce Medal (2006) for lifetime contributions in astronomy. This year the world celebrates the International Year of Astronomy, commemorating the accomplishments of Galileo. There are great parallels between Frank and Galileo. After developing a revolutionary low-temperature detector, Frank re-engineered and optimized telescopes for infrared performance. He not only oriented them to the heavens but also placed them there throughout Earth's atmosphere and to the Moon. He made fantastic new discoveries from the Sun throughout the Universe. He radically changed the way the entire world looks at the Universe and impacted generations of new scientists as well as the general public. Frank's level of innovation is stunning and diverse. Chopping and undersized secondary mirrors, cold baffling, cryogenic designs, "Low Dewars," Helium-3 systems, JFET amplifiers for the IRAS satellite, airborne astronomy, the silver-coated 28-inch survey telescope, the MMT, the 36-foot radio dish, Apollo 17 radiometer, television detector systems, infrared microscopes, and on and on. His insights enabled the IRAS and Spitzer missions and contributed to Spacelab2, KAO, SOFIA, NICMOS/HST, JWST, etc. He also established a small business (Infrared Laboratories Inc.) that for more than 40 years has supplied instrumentation to astronomers and semi

  13. Thermal decomposition of sodium amide, NaNH2, and sodium amide hydroxide composites, NaNH2-NaOH.

    PubMed

    Jepsen, Lars H; Wang, Peikun; Wu, Guotao; Xiong, Zhitao; Besenbacher, Flemming; Chen, Ping; Jensen, Torben R

    2016-09-14

    Sodium amide, NaNH 2 , has recently been shown to be a useful catalyst to decompose NH 3 into H 2 and N 2 , however, sodium hydroxide is omnipresent and commercially available NaNH 2 usually contains impurities of NaOH (<2%). The thermal decomposition of NaNH 2 and NaNH 2 -NaOH composites is systematically investigated and discussed. NaNH 2 is partially dissolved in NaOH at T > 100 °C, forming a non-stoichiometric solid solution of Na(OH) 1-x (NH 2 ) x (0 < x < ∼0.30), which crystallizes in an orthorhombic unit cell with the space group P2 1 2 1 2 1 determined by synchrotron powder X-ray diffraction. The composite xNaNH 2 -(1 - x)NaOH (∼0.70 < x < 0.72) shows a lowered melting point, ∼160 °C, compared to 200 and 318 °C for neat NaNH 2 and NaOH, respectively. We report that 0.36 mol of NH 3 per mol of NaNH 2 is released below 400 °C during heating in an argon atmosphere, initiated at its melting point, T = 200 °C, possibly due to the formation of the mixed sodium amide imide solid solution. Furthermore, NaOH reacts with NaNH 2 at elevated temperatures and provides the release of additional NH 3 .

  14. Condition of Si crystal formation by vaporizing Na from NaSi

    NASA Astrophysics Data System (ADS)

    Morito, Haruhiko; Karahashi, Taiki; Yamane, Hisanori

    2012-09-01

    NaSi was heated at various Na vapor pressures (pNa 0.1-1.2 atm) and temperatures (973-1173 K) to investigate the condition of Si crystal formation from NaSi by Na evaporation. Silicon single crystals 1-3 mm in diameter were grown by evaporation of Na from Na-Si melt at 1173 K and pNa=0.74 atm.

  15. Sodium iron hexacyanoferrate with high Na content as a Na-rich cathode material for Na-ion batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    You, Ya; Yu, Xi -Qian; Yin, Ya -Xia

    Owing to the worldwide abundance and low-cost of Na, room-temperature Na-ion batteries are emerging as attractive energy storage systems for large-scale grids. Increasing the Na content in cathode material is one of the effective ways to achieve high energy density. Prussian blue and its analogues (PBAs) are promising Na-rich cathode materials since they can theoretically store two Na ions per formula. However, increasing the Na content in PBAs cathode materials is a big challenge in the current. Here we show that sodium iron hexacyanoferrate with high Na content could be obtained by simply controlling the reducing agent and reaction atmospheremore » during synthesis. The Na content can reach as high as 1.63 per formula, which is the highest value for sodium iron hexacyanoferrate. This Na-rich sodium iron hexacyanoferrate demonstrates a high specific capacity of 150 mA h g -1 and remarkable cycling performance with 90% capacity retention after 200 cycles. Furthermore, the Na intercalation/de-intercalation mechanism is systematically studied by in situ Raman, X-ray diffraction and X-ray absorption spectroscopy analysis for the first time. As a result, the Na-rich sodium iron hexacyanoferrate could function as a plenteous Na reservoir and has great potential as a cathode material toward practical Na-ion batteries.« less

  16. Sodium iron hexacyanoferrate with high Na content as a Na-rich cathode material for Na-ion batteries

    DOE PAGES

    You, Ya; Yu, Xi -Qian; Yin, Ya -Xia; ...

    2014-10-27

    Owing to the worldwide abundance and low-cost of Na, room-temperature Na-ion batteries are emerging as attractive energy storage systems for large-scale grids. Increasing the Na content in cathode material is one of the effective ways to achieve high energy density. Prussian blue and its analogues (PBAs) are promising Na-rich cathode materials since they can theoretically store two Na ions per formula. However, increasing the Na content in PBAs cathode materials is a big challenge in the current. Here we show that sodium iron hexacyanoferrate with high Na content could be obtained by simply controlling the reducing agent and reaction atmospheremore » during synthesis. The Na content can reach as high as 1.63 per formula, which is the highest value for sodium iron hexacyanoferrate. This Na-rich sodium iron hexacyanoferrate demonstrates a high specific capacity of 150 mA h g -1 and remarkable cycling performance with 90% capacity retention after 200 cycles. Furthermore, the Na intercalation/de-intercalation mechanism is systematically studied by in situ Raman, X-ray diffraction and X-ray absorption spectroscopy analysis for the first time. As a result, the Na-rich sodium iron hexacyanoferrate could function as a plenteous Na reservoir and has great potential as a cathode material toward practical Na-ion batteries.« less

  17. Compensatory regulation of Na+ absorption by Na+/H+ exchanger and Na+-Cl- cotransporter in zebrafish (Danio rerio)

    PubMed Central

    2013-01-01

    Introduction In mammals, internal Na+ homeostasis is maintained through Na+ reabsorption via a variety of Na+ transport proteins with mutually compensating functions, which are expressed in different segments of the nephrons. In zebrafish, Na+ homeostasis is achieved mainly through the skin/gill ionocytes, namely Na+/H+ exchanger (NHE3b)-expressing H+-ATPase rich (HR) cells and Na+-Cl- cotransporter (NCC)-expressing NCC cells, which are functionally homologous to mammalian proximal and distal convoluted tubular cells, respectively. The present study aimed to investigate whether or not the functions of HR and NCC ionocytes are differentially regulated to compensate for disruptions of internal Na+ homeostasis and if the cell differentiation of the ionocytes is involved in this regulation pathway. Results Translational knockdown of ncc caused an increase in HR cell number and a resulting augmentation of Na+ uptake in zebrafish larvae, while NHE3b loss-of-function caused an increase in NCC cell number with a concomitant recovery of Na+ absorption. Environmental acid stress suppressed nhe3b expression in HR cells and decreased Na+ content, which was followed by up-regulation of NCC cells accompanied by recovery of Na+ content. Moreover, knockdown of ncc resulted in a significant decrease of Na+ content in acid-acclimated zebrafish. Conclusions These results provide evidence that HR and NCC cells exhibit functional redundancy in Na+ absorption, similar to the regulatory mechanisms in mammalian kidney, and suggest this functional redundancy is a critical strategy used by zebrafish to survive in a harsh environment that disturbs body fluid Na+ homeostasis. PMID:23924428

  18. Hydrogen-fluorine exchange in NaBH4-NaBF4.

    PubMed

    Rude, L H; Filsø, U; D'Anna, V; Spyratou, A; Richter, B; Hino, S; Zavorotynska, O; Baricco, M; Sørby, M H; Hauback, B C; Hagemann, H; Besenbacher, F; Skibsted, J; Jensen, T R

    2013-11-07

    Hydrogen-fluorine exchange in the NaBH4-NaBF4 system is investigated using a range of experimental methods combined with DFT calculations and a possible mechanism for the reactions is proposed. Fluorine substitution is observed using in situ synchrotron radiation powder X-ray diffraction (SR-PXD) as a new Rock salt type compound with idealized composition NaBF2H2 in the temperature range T = 200 to 215 °C. Combined use of solid-state (19)F MAS NMR, FT-IR and DFT calculations supports the formation of a BF2H2(-) complex ion, reproducing the observation of a (19)F chemical shift at -144.2 ppm, which is different from that of NaBF4 at -159.2 ppm, along with the new absorption bands observed in the IR spectra. After further heating, the fluorine substituted compound becomes X-ray amorphous and decomposes to NaF at ~310 °C. This work shows that fluorine-substituted borohydrides tend to decompose to more stable compounds, e.g. NaF and BF3 or amorphous products such as closo-boranes, e.g. Na2B12H12. The NaBH4-NaBF4 composite decomposes at lower temperatures (300 °C) compared to NaBH4 (476 °C), as observed by thermogravimetric analysis. NaBH4-NaBF4 (1:0.5) preserves 30% of the hydrogen storage capacity after three hydrogen release and uptake cycles compared to 8% for NaBH4 as measured using Sievert's method under identical conditions, but more than 50% using prolonged hydrogen absorption time. The reversible hydrogen storage capacity tends to decrease possibly due to the formation of NaF and Na2B12H12. On the other hand, the additive sodium fluoride appears to facilitate hydrogen uptake, prevent foaming, phase segregation and loss of material from the sample container for samples of NaBH4-NaF.

  19. Obituary: Robert Fleischer, 1918-2001

    NASA Astrophysics Data System (ADS)

    Boyce, Peter Bradford; Saffell, Mary E.

    2003-12-01

    Robert Fleischer was born 20 August 1918 to Leon and Rose Fleischer in Flushing, NY. He was educated at Harvard, receiving his BS in 1940, MA in 1947, and PhD in 1949. He specialized in geophysics and solar-terrestrial relations. Fleischer joined the faculty at Rensselaer Polytechnic Institute advancing from Assistant to Full professor in 1958. As Director of the RPI Observatory, Fleischer attempted to bring modern astronomy to the institutions in the Albany area by procuring the funds to build a radio telescope. He left for the National Science Foundation (NSF) before the observatory was completed. It is a testament to his character that without his enormous energy, organizational, and fundraising abilities, the radio telescope project languished after he left. Fleischer joined the NSF in 1962 as the Program Director for Solar-Terrestrial Research. He was the government-wide Coordinator for the International Quiet Sun Years, and coordinated the 1966 South American Eclipse expeditions. Thereafter, he was appointed Deputy Head of the Office of International Science Activities. Fleischer is most notably remembered as the head of the Astronomy Section at the National Science Foundation. He brought astronomy into its own at NSF and involved the community in a major way through use of advisory committees. He was dedicated to helping the astronomical community understand the funding system, the political environment, and the various factors in how money is allocated. Fleischer truly believed in the concept that scientists should be making the important decisions about their field. He was instrumental in injecting science into the oversight of the National Observatories. Relations with the community say a lot about the man, the complexities of his character, and the forces that drove him. Fleischer was passionate in his beliefs and in his devotion to doing the best for astronomy. His strong approach and belief in himself served him well in many ways, but caused him grief

  20. [From the Auschwitz Syndrome to a Psyche Model--Life and Work of the Polish Psychiatrist Antoni Kepinski (1918-1972)].

    PubMed

    Schochow, Maximilian; Willer, Manuel; Steger, Florian

    2016-01-01

    Life and work of the Polish psychiatrist Antoni Kepinski (1918 - 1972) are barely known today, although his writings about the Auschwitz syndrome have had an impact all over the world. We present his biography and work. Compilation and evaluation of literature about Kepinski's work and historical-critical analysis of his key texts. Kepinski's work about the Auschwitz syndrome formed the basis for his understanding of the psyche and his theory on information metabolism. Kepinski posited that the mind processes outside stimuli based on its own set of values and that it determines the subject's actions. In doing so, it affects its environment. If these interactions are disrupted, pathological disorders might result. The therapist should consequently empower the patient to get in touch with his own value-system. Kepinskis work serves as a foundation for research on disease patterns that are known today as post-traumatic stress disorder (PTSD). His theory on information metabolism is essential for the current treatment of patients. It is therefore important to further explore his work and adjust it to the requirements of medical practice. © Georg Thieme Verlag KG Stuttgart · New York.

  1. Obituary: James H. "Trex" Trexler, 1918-2005

    NASA Astrophysics Data System (ADS)

    Barker, Ed

    2007-12-01

    James H. "Trex" Trexler, Naval Center for Space Technology, a retired scientist and astronomer, with a 50-year career at NRL died of cancer on October 22, 2005, at the age of 87. Born in Missoula, Montana (May 18, 1918), he grew up in Dallas, Texas, and attended Southern Methodist University (SMU) Engineering School. He combined his interests in astronomy and radio communication and operated the observatory on the SMU campus. Mr. Trexler had a most interesting and rewarding career at NRL, which resulted in notable contributions in scientific and technical developments. While at SMU, he worked on a government-sponsored project on radio detection and tracking of meteors. This work resulted in a call from NRL in 1942 to join the Navy radio detection effort being mounted against the German submarine Wolf Packs that were harassing our North Atlantic convoys on the supply routes to our European Allies. The program proved highly successful causing the breakup of the German Pack operation, and resulted in the sinking and capturing of many U-boats. After World War II, Trex and H. O. Lorenzen brought the German Navy's very advanced Wullenweber Direction Finder back to NRL, and rebuilt it at the Washington Coast Guard Station, south of Alexandria. It served as the prototype for the Direction Finder at the heart of the Navy and Air Force intercept networks and later as the first tracker of the Soviet Sputnik. He received the Navy Meritorious Civilian Service Award for his efforts. In the late l940s, Trex built the radar intercept equipment for the Navy's P4M Airborne Cold War Ferret Program. This capability provided instantaneous frequency and direction of arrival against Soviet radars from high-altitude flights along the Soviet borders. His Radio Physics Branch developed a surface mobile intercept system deployed to the Near East for which the Navy made the first group cash incentive award. With the beginning of the space age, his branch examined the moon as a possible

  2. Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes

    PubMed Central

    Lu, Fang-Min

    2017-01-01

    Decades ago, it was proposed that Na transport in cardiac myocytes is modulated by large changes in cytoplasmic Na concentration within restricted subsarcolemmal spaces. Here, we probe this hypothesis for Na/K pumps by generating constitutive transsarcolemmal Na flux with the Na channel opener veratridine in whole-cell patch-clamp recordings. Using 25 mM Na in the patch pipette, pump currents decay strongly during continuous activation by extracellular K (τ, ∼2 s). In contradiction to depletion hypotheses, the decay becomes stronger when pump currents are decreased by hyperpolarization. Na channel currents are nearly unchanged by pump activity in these conditions, and conversely, continuous Na currents up to 0.5 nA in magnitude have negligible effects on pump currents. These outcomes are even more pronounced using 50 mM Li as a cytoplasmic Na congener. Thus, the Na/K pump current decay reflects mostly an inactivation mechanism that immobilizes Na/K pump charge movements, not cytoplasmic Na depletion. When channel currents are increased beyond 1 nA, models with unrestricted subsarcolemmal diffusion accurately predict current decay (τ ∼15 s) and reversal potential shifts observed for Na, Li, and K currents through Na channels opened by veratridine, as well as for Na, K, Cs, Li, and Cl currents recorded in nystatin-permeabilized myocytes. Ion concentrations in the pipette tip (i.e., access conductance) track without appreciable delay the current changes caused by sarcolemmal ion flux. Importantly, cytoplasmic mixing volumes, calculated from current decay kinetics, increase and decrease as expected with osmolarity changes (τ >30 s). Na/K pump current run-down over 20 min reflects a failure of pumps to recover from inactivation. Simulations reveal that pump inactivation coupled with Na-activated recovery enhances the rapidity and effectivity of Na homeostasis in cardiac myocytes. In conclusion, an autoregulatory mechanism enhances cardiac Na/K pump activity when

  3. We could learn much more from 1918 pandemic-the (mis)fortune of research relying on original death certificates.

    PubMed

    Alonso, Wladimir J; Nascimento, Francielle C; Chowell, Gerardo; Schuck-Paim, Cynthia

    2018-05-01

    The analysis of historical death certificates has enormous potential for understanding how the health of populations was shaped by diseases and epidemics and by the implementation of specific interventions. In Brazil, the systematic archiving of mortality records was initiated only in 1944-hence the analysis of death registers before this time requires searching for these documents in public archives, notaries, parishes, and especially ancient cemeteries, which are often the only remaining source of information about these deaths. This article describes an effort to locate original death certificates in Brazil and document their organization, accessibility, and preservation. To this end, we conducted an exploratory study in 19 of the 27 Brazilian states, focusing on the period surrounding the 1918 influenza pandemic (1913-1921). We included 55 cemeteries, 22 civil archives, and one military archive. Apart from few exceptions, the results show the absence of a curatorial policy for the organization, access or even physical preservation of this material, frequently leading to unavailability, deterioration, and ultimately its complete loss. This study indicates the need to promote the preservation of a historical heritage that is a key to understanding historical epidemiological patterns and human responses to global health threats. Copyright © 2018 Elsevier Inc. All rights reserved.

  4. [History of pandemic influenza in Japan].

    PubMed

    Matsumoto, Keizo

    2010-09-01

    In Japan, influenza like epidemics were described many times since Heian era. However, Spanish flu as the modern medicine invaded Japan in 1918, thus almost infected 390,000 patients died with associated pneumonia. After the discovery of influenza virus in 1933, Japan experienced pandemic influenza--Asian flu(H2N2) in 1957. After about 10 years, Hong Kong flu (H3N2) came to Japan at 1968. However, we had many reliable antibiotics but had not any antiviral drug at the early time. After year 2000, we fortunately obtained reliable three antiviral drugs such as amantadine, oseltamivir and zanamivir. Moreover, very useful rapid test kits for influenza A and B viruses were developed and used in Japan. 2009 H1N1 influenza epidemic occured in Japan after the great epidemic in Mexico and North America but elderly patient was few. With together, host conditions regarding with high risk are changing. Lessons from past several pandemic influenza are those that many issues for changing high risk conditions, viral genetic changes, developing antiviral agents, developing new useful vaccins and determinating bacterial secondary pathogens are important.

  5. Na+/Ca2+ exchange and Na+/K+-ATPase in the heart

    PubMed Central

    Shattock, Michael J; Ottolia, Michela; Bers, Donald M; Blaustein, Mordecai P; Boguslavskyi, Andrii; Bossuyt, Julie; Bridge, John H B; Chen-Izu, Ye; Clancy, Colleen E; Edwards, Andrew; Goldhaber, Joshua; Kaplan, Jack; Lingrel, Jerry B; Pavlovic, Davor; Philipson, Kenneth; Sipido, Karin R; Xie, Zi-Jian

    2015-01-01

    This paper is the third in a series of reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation–contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on cardiac Na+/Ca2+ exchange (NCX) and Na+/K+-ATPase (NKA). While the relevance of Ca2+ homeostasis in cardiac function has been extensively investigated, the role of Na+ regulation in shaping heart function is often overlooked. Small changes in the cytoplasmic Na+ content have multiple effects on the heart by influencing intracellular Ca2+ and pH levels thereby modulating heart contractility. Therefore it is essential for heart cells to maintain Na+ homeostasis. Among the proteins that accomplish this task are the Na+/Ca2+ exchanger (NCX) and the Na+/K+ pump (NKA). By transporting three Na+ ions into the cytoplasm in exchange for one Ca2+ moved out, NCX is one of the main Na+ influx mechanisms in cardiomyocytes. Acting in the opposite direction, NKA moves Na+ ions from the cytoplasm to the extracellular space against their gradient by utilizing the energy released from ATP hydrolysis. A fine balance between these two processes controls the net amount of intracellular Na+ and aberrations in either of these two systems can have a large impact on cardiac contractility. Due to the relevant role of these two proteins in Na+ homeostasis, the emphasis of this review is on recent developments regarding the cardiac Na+/Ca2+ exchanger (NCX1) and Na+/K+ pump and the controversies that still persist in the field. PMID:25772291

  6. Acidosis Differentially Modulates Inactivation in NaV1.2, NaV1.4, and NaV1.5 Channels

    PubMed Central

    Vilin, Yury Y.; Peters, Colin H.; Ruben, Peter C.

    2012-01-01

    NaV channels play a crucial role in neuronal and muscle excitability. Using whole-cell recordings we studied effects of low extracellular pH on the biophysical properties of NaV1.2, NaV1.4, and NaV1.5, expressed in cultured mammalian cells. Low pH produced different effects on different channel subtypes. Whereas NaV1.4 exhibited very low sensitivity to acidosis, primarily limited to partial block of macroscopic currents, the effects of low pH on gating in NaV1.2 and NaV1.5 were profound. In NaV1.2 low pH reduced apparent valence of steady-state fast inactivation, shifted the τ(V) to depolarizing potentials and decreased channels availability during onset to slow and use-dependent inactivation (UDI). In contrast, low pH delayed open-state inactivation in NaV1.5, right-shifted the voltage-dependence of window current, and increased channel availability during onset to slow and UDI. These results suggest that protons affect channel availability in an isoform-specific manner. A computer model incorporating these results demonstrates their effects on membrane excitability. PMID:22701426

  7. Reconstructing Harry: a genealogical study of a colonial family 'inside' and 'outside' the Grahamstown Asylum, 1888-1918.

    PubMed

    Wilbraham, Lindy

    2014-04-01

    Recent scholarship has explored the dynamics between families and colonial lunatic asylums in the late nineteenth century, where families actively participated in the processes of custodial care, committal, treatment and release of their relatives. This paper works in this historical field, but with some methodological and theoretical differences. The Foucauldian study is anchored to a single case and family as an illness narrative that moves cross-referentially between bureaucratic state archival material, psychiatric case records, and intergenerational family-storytelling and family photographs. Following headaches and seizures, Harry Walter Wilbraham was medically boarded from his position as Postmaster in the Cape of Good Hope Colony of South Africa with a 'permanent disease of the brain', and was committed to the Grahamstown Asylum in 1910, where he died the following year, aged 40 years. In contrast to writings about colonial asylums that usually describe several patient cases and thematic patterns in archival material over time and place, this study's genealogical lens examines one white settler male patient's experiences within mental health care in South Africa between 1908 and 1911. The construction of Harry's 'case' interweaves archival sources and reminiscences inside and outside the asylum, and places it within psychiatric discourse of the time, and family dynamics in the years that followed. Thus, this case study maps the constitution of 'patient' and 'family' in colonial life, c.1888-1918, and considers the calamity, uncertainty, stigma and silences of mental illness.

  8. Role of Na+ conductance, Na+-H+ exchange, and Na+-K+-2Cl− symport in the regulatory volume increase of rat hepatocytes

    PubMed Central

    Wehner, Frank; Tinel, Hanna

    1998-01-01

    In rat hepatocytes under hypertonic stress, the entry of Na+ (which is thereafter exchanged for K+ via Na+-K+-ATPase) plays the key role in regulatory volume increase (RVI).In the present study, the contributions of Na+ conductance, Na+-H+ exchange and Na+-K+-2Cl− symport to this process were quantified in confluent primary cultures by means of intracellular microelectrodes and cable analysis, microfluorometric determinations of cell pH and buffer capacity, and measurements of frusemide (furosemide)/bumetanide-sensitive 86Rb+ uptake, respectively. Osmolarity was increased from 300 to 400 mosmol l−1 by addition of sucrose.The experiments indicate a relative contribution of approximately 4:1:1 to hypertonicity-induced Na+ entry for the above-mentioned transporters and the overall Na+ yield equalled 51 mmol l−1 (10 min)−1.This Na+ gain is in good agreement with the stimulation of Na+ extrusion via Na+-K+-ATPase plus the actual increase in cell Na+, namely 55 mmol l−1 (10 min)−1, as was determined on the basis of ouabain-sensitive 86Rb+ uptake and by means of Na+-sensitive microelectrodes, respectively.The overall increase in Na+ and K+ activity plus the expected concomitant increase in cell Cl− equalled 68 mmol l−1, which fits well with the increase in osmotic activity expected to occur from an initial cell shrinkage to 87.5 % and a RVI to 92.6 % of control, namely 53 mosmol l−1.The prominent role of Na+ conductance in the RVI of rat hepatocytes could be confirmed on the basis of the pharmacological profile of this process, which was characterized by means of confocal laser-scanning microscopy. PMID:9481677

  9. 1903 manuscript revived: Cerebral disturbances in multiple sclerosis (Des troubles cérébraux dans la sclérose en plaques) by Raymond Cestan (1872-1933) and Claudien Philippe (1866-1903).

    PubMed

    Walusinski, O

    2015-04-01

    Philanthropy aimed at helping medical research has been around for a long time. In the 19th century, cash awards were distributed by the French Academy of Medicine according to criteria determined by each generous donor. It was thus that Mrs. Bernard de Civrieux endowed the Academy each year with the task of supporting one or more laureates whose work furthered understanding of "nervous diseases". In 1903, Raymond Cestan (1872-1933) and Claudien Philippe (1866-1903) were selected for their dissertation on "cerebral disturbances" during multiple sclerosis with clinical as well as anatomical-pathological effects. Never published, this innovative manuscript, taken from the library of Fulgence Raymond (1844-1910), will be analysed here after a brief biography of each author. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  10. Kinetic contribution to extracellular Na+/K+ selectivity in the Na+/K+ pump.

    PubMed

    Vleeskens, Elizabeth; Clarke, Ronald J

    2018-05-01

    The sodium potassium pump (Na + ,K + -ATPase) shows a high selectivity for K + over Na + binding from the extracellular medium. To understand the K + selectivity in the presence of a high concentration of competing Na + ions requires consideration of more than just ion binding affinities. Here, equilibrium-based calculations of the extracellular occupation of the Na + ,K + -ATPase transport sites by Na + and K + are compared to fluxes through Na + and K + transport pathways. The results show that, under physiological conditions, there is a 332-fold selectivity for pumping of K + from the extracellular medium into the cytoplasm relative to Na + , whereas equilibrium calculations alone predict only a 7.5-fold selectivity for K + . Thus, kinetic effects make a major contribution to the determination of extracellular K + selectivity.

  11. Obituary: Per E. Maltby, 1933-2006

    NASA Astrophysics Data System (ADS)

    Kjeldseth-Moe, Olav

    2007-12-01

    Professor Per Maltby, prominent Norwegian Solar Physicist at the Institute of Theoretical Astrophysics, University of Oslo, Norway, died on 24 May 2006. Lung cancer was diagnosed in February, but he was expected to improve. Until the end of March he came to his office every day, got recent papers off the web, and followed his field closely as he had always done. Per Maltby was born in Oslo, Norway, on 3 November 1933. He started his studies at the University of Oslo in 1952 and took his candidate degree in 1957. Between 1955 and 1958 he was a research assistant at the Institute of Theoretical Astrophysics in Oslo. In 1960 Maltby became an assistant professor (amanuensis) at the University of Bergen and from January 1963 he held a corresponding position at the University of Oslo. He became an associate professor in 1967, and from 1983 until he retired in 2003 he was a full Professor at the Institute of Theoretical Astrophysics, University of Oslo. Per Maltby is survived by his wife Elisabet (née Ruud), whom he married in 1956. They had two children. The daughter, Bente, is a medical doctor and gynecologist serving as a section head at the district hospital in Kristiansand in southern Norway. Their son, Lars, holds a doctoral degree in engineering, specializing in the properties of powders. He is currently managing director in the Norwegian division of the French multinational company Saint Gobain. As a father Per Maltby expressed pride in his children and was pleased with their progress in life. He also enjoyed his five grandchildren. As a scientist, Per Maltby was versatile and productive. In the early 1960s he visited the California Institute of Technology where he did pioneering studies of the distribution and time variation of the radio emission from active galaxies, using the Owens Valley Radio Observatory. His work with Alan Moffet contributed to revealing the secrets of these remote objects. Their results drew attention and were indeed mentioned in the pages

  12. Na and K Dependence of the Na/K Pump in Cystic Fibrosis Fibroblasts

    NASA Astrophysics Data System (ADS)

    Reznik, Vivian M.; Schneider, Jerry A.; Mendoza, Stanley A.

    1981-11-01

    The Na and K dependence of the Na/K pump was measured in skin fibroblasts from patients with cystic fibrosis and age/sex-matched controls. Under basal conditions, there was no difference between control and cystic fibrosis cells in protein per cell, intracellular Na and K content, or Na/K pump activity (measured as ouabain-sensitive 86Rb uptake). There was no difference in the Na dependence of the Na/K pump between cystic fibrosis cells and control cells. In cells from patients with cystic fibrosis, the Na/K pump had a significantly lower affinity for K (Km = 1.6 mM) when compared to normals (Km = 0.9 mM). This difference was demonstrated by using two independent experimental designs.

  13. O 'Iluminismo' na Alemanha--As Concepcoes de Mendelssohn e Kant (The 'Enlightenment' in Germany--The Concepts of Mendelssohn and Kant).

    ERIC Educational Resources Information Center

    Mainka, Peter Johann

    2000-01-01

    States that in 1783 J. F. Zollner, a Berlin theologian, asked the question: "What is 'Enlightenment'?" Notes that the next year Immanuel Kant and Moses Mendelssohn gave definitions of the Enlightenment that are famous in the history of ideas. Analyzes and discusses the definitions through keywords such as reason, criticism, and…

  14. Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions.

    PubMed

    Thiangtum, Wandee; Schonewille, J Thomas; Verstegen, Martin Wa; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H

    2017-06-01

    Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the subsequent rate of repletion. The rate of Na depletion and subsequent rate of Na repletion with two levels of dietary Na to lactating dairy cows housed under tropical conditions were investigated using the salivary Na/K. The 12 lactating cows (salivary Na/K ratio 14.6) rapidly developed clinical signs of Na deficiency, including pica, polyuria and polydipsia, reduced body weight and reduced milk yield when fed a low-Na ration (0.33 g kg -1 dry matter (DM)) for 3 weeks. Deficiency symptoms were associated with a rapid decrease in salivary Na/K ratio to <4.3 from 7 to 21 days. Subsequent repletion of the cows with NaCl to a ration concentration of 1.1 or 1.6 g Na kg -1 DM for 5 weeks did not restore salivary Na/K ratio to values of >6. A daily Na intake of heat-stressed lactating cows to a ration intake of 1.6 g Na kg -1 DM was insufficient to restore Na deficiency. One week was sufficient to deplete heat-stressed lactating cows of Na, allowing for rapid dose-response studies utilizing the salivary Na/K ratio as a parameter for Na status of cows under tropical conditions. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  15. First World War and Mental Health: a retrospective comparative study of veterans admitted to a psychiatric hospital between 1915 and 1918.

    PubMed

    Lagonia, Paolo; Aloi, Matteo; Magliocco, Fabio; Cerminara, Gregorio; Segura-Garcia, Cristina; Del Vecchio, Valeria; Luciano, Mario; Fiorillo, Andrea; De Fazio, Pasquale

    2017-01-01

    The association between mental illness and war has been repeatedly investigated. Higher levels of depressive symptoms and an increased suicidal risk have been found in veterans. In this study we investigated the mental health conditions among Italian soldiers during the “Great War”, who were hospitalized in a mental health hospital in Italy. The study sample consists of 498 soldiers who were admitted during the World War I between 1915 and 1918, and 498 civilian patients admitted in two different periods (1898-1914, 1919- 1932). Psychiatric diagnoses have been recorded retrospectively by a detailed examination of clinical records. Socio-demographic informations, diagnosis at first admission, number of admissions, and deployment in war zones were collected. A logistic regression analysis was performed, the diagnosis of depression was considered as dependent variable while clinical and demographic variables as independent predictors. Soldiers deployed in war zones were more likely to have a diagnosis of depression compared to those not serving on the frontline. The logistic regression analysis showed that the diagnosis of depression is predicted by being a soldier and being deployed in a war area. Our data confirm that soldiers engaged in war are at higher risk of developing depression compared to non-deployed soldiers.

  16. Obituary: Raymond Edwin White Jr., 1933-2004

    NASA Astrophysics Data System (ADS)

    Liebert, James William

    2004-12-01

    Raymond E. White, Jr., died unexpectedly at his home, in the early morning hours of October 12, 2004. Death appears to have been caused by severe diabetic shock. He retired from the Department of Astronomy/Steward Observatory in July 1999 with the title of University Distinguished Professor, after serving on the faculty of this institution for over 35 years. He was born in Freeport, Illinois, on 6 May 1933, to Beatrice and Raymond E, Sr. -the latter being a career soldier in the US Army. Ray's early schooling took place in Illinois, New Jersey, Germany and Switzerland, following his father's assignments. He obtained a bachelors degree from the University of Illinois in 1955. Next Ray enlisted in the US Army, but quickly was enrolled in Officer Candidate School. He then served as lst Lt. in the US Army Corps of Engineers. Although military affairs remained a lifelong interest, and he was a member of the Company of Military Historians, Ray decided after three years to return to academia. He entered the astronomy PhD program at the University of Illinois in 1958. His PhD dissertation was supervised by Ivan R. King. Ray accepted a faculty position at the University of Arizona in 1964. First and foremost, Ray White was known at Arizona as an excellent teacher, revered by a large number of former students. When the astronomy major program was begun in 1967, Ray was one of three, original, major advisors. Over the next three decades, he was a leader at the University level in reforming the undergraduate program and courses. He was selected Outstanding University Faculty Member in April 1989 and he served as one of a handful of professors who are Faculty Fellows. These Fellows devote untold hundreds of hours as part-time residents at student dormitories, to give students a friendly face to address their problems. In 1995, Ray was among the first group of faculty to be recognized as University Distinguished Professors. In the year of his retirement, 1999, University

  17. Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion.

    PubMed

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J; Rasmussen, Helge H

    2016-03-08

    The existence of a subsarcolemmal space with restricted diffusion for Na(+) in cardiac myocytes has been inferred from a transient peak electrogenic Na(+)-K(+) pump current beyond steady state on reexposure of myocytes to K(+) after a period of exposure to K(+)-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na(+) that accumulated in the diffusion-restricted space during pump inhibition in K(+)-free extracellular solution. However, there are no known physical barriers that account for such restricted Na(+) diffusion, and we examined if changes of activity of the Na(+)-K(+) pump itself cause the transient peak current. Reexposure to K(+) reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na(+) concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K(+)-free pipette solution could not be reconciled with restricted subsarcolemmal Na(+) diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na(+)- and K(+) concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na(+)-K(+) pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na(+)-K(+) pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K(+)-induced peak Na(+)-K(+) pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K(+)-induced peak Na(+)-K(+) pump current reflects the effect

  18. Glutathionylation-Dependence of Na+-K+-Pump Currents Can Mimic Reduced Subsarcolemmal Na+ Diffusion

    PubMed Central

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J.; Rasmussen, Helge H.

    2016-01-01

    The existence of a subsarcolemmal space with restricted diffusion for Na+ in cardiac myocytes has been inferred from a transient peak electrogenic Na+-K+ pump current beyond steady state on reexposure of myocytes to K+ after a period of exposure to K+-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na+ that accumulated in the diffusion-restricted space during pump inhibition in K+-free extracellular solution. However, there are no known physical barriers that account for such restricted Na+ diffusion, and we examined if changes of activity of the Na+-K+ pump itself cause the transient peak current. Reexposure to K+ reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na+ concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K+-free pipette solution could not be reconciled with restricted subsarcolemmal Na+ diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na+- and K+ concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na+-K+ pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na+-K+ pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K+-induced peak Na+-K+ pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K+-induced peak Na+-K+ pump current reflects the effect of conformation-dependent β1 pump subunit

  19. Cytosolic Na+ Controls an Epithelial Na+ Channel Via the Go Guanine Nucleotide-Binding Regulatory Protein

    NASA Astrophysics Data System (ADS)

    Komwatana, P.; Dinudom, A.; Young, J. A.; Cook, D. I.

    1996-07-01

    In tight Na+-absorbing epithelial cells, the rate of Na+ entry through amiloride-sensitive apical membrane Na+ channels is matched to basolateral Na+ extrusion so that cell Na+ concentration and volume remain steady. Control of this process by regulation of apical Na+ channels has been attributed to changes in cytosolic Ca2+ concentration or pH, secondary to changes in cytosolic Na+ concentration, although cytosolic Cl- seems also to be involved. Using mouse mandibular gland duct cells, we now demonstrate that increasing cytosolic Na+ concentration inhibits apical Na+ channels independent of changes in cytosolic Ca2+, pH, or Cl-, and the effect is blocked by GDP-β -S, pertussis toxin, and antibodies against the α -subunits of guanine nucleotide-binding regulatory proteins (Go). In contrast, the inhibitory effect of cytosolic anions is blocked by antibodies to inhibitory guanine nucleotide-binding regulatory proteins (Gi1/Gi2. It thus appears that apical Na+ channels are regulated by Go and Gi proteins, the activities of which are controlled, respectively, by cytosolic Na+ and Cl-.

  20. Superconductivity could occur Na-supersaturated NaCl

    NASA Astrophysics Data System (ADS)

    Hanaki, Koji

    1997-04-01

    A flow-into electron and a flow-out hole mean flow-into of two unit electric c harges. Even if an exciton consisting of an electron and a hole is a neutral q uasi-particle, overlapping of excitons, namely, the bose condensation changes into a superconductor where half the electric current is due to holes moving t oward the reverse direction. The Meisner effect of the bose condensation comes from the precession of the each exciton under the magnetic field^1. Moreo ver, the present mechanism is supported with that superconducting material alw ays has two kinds of carriers. The superconductivity of NaCl comes from the ab ove-mentioned theory. Free stable holes at first and then electrons are produc ed in NaCl when considerable number of Cl^- lattice vacancies are brought in NaCl mainly because some electrons in the Cl-3p filled band fall into the v acancies. The coexistence of two kinds of stable carriers does not always mean the presence of excitons like VO with electrons not paired and localized in e ach V atom though. While, the absorption spectrum of the NaCl has already conf irmed the presence of excitons; the strength of the spectrum seems to indicate the formation of the bose condensation. Thus we could expect a new supercondu ctor. 1) Hanaki B.Am.P.Soc.,40-1(1995)568

  1. DOR activation inhibits anoxic/ischemic Na+ influx through Na+ channels via PKC mechanisms in the cortex.

    PubMed

    Chao, Dongman; He, Xiaozhou; Yang, Yilin; Bazzy-Asaad, Alia; Lazarus, Lawrence H; Balboni, Gianfranco; Kim, Dong H; Xia, Ying

    2012-08-01

    Activation of delta-opioid receptors (DOR) is neuroprotective against hypoxic/ischemic injury in the cortex, which is at least partially related to its action against hypoxic/ischemic disruption of ionic homeostasis that triggers neuronal injury. Na(+) influx through TTX-sensitive voltage-gated Na(+) channels may be a main mechanism for hypoxia-induced disruption of K(+) homeostasis, with DOR activation attenuating the disruption of ionic homeostasis by targeting voltage-gated Na(+) channels. In the present study we examined the role of DOR in the regulation of Na(+) influx in anoxia and simulated ischemia (oxygen-glucose deprivation) as well as the effect of DOR activation on the Na(+) influx induced by a Na(+) channel opener without anoxic/ischemic stress and explored a potential PKC mechanism underlying the DOR action. We directly measured extracellular Na(+) activity in mouse cortical slices with Na(+) selective electrodes and found that (1) anoxia-induced Na(+) influx occurred mainly through TTX-sensitive Na(+) channels; (2) DOR activation inhibited the anoxia/ischemia-induced Na(+) influx; (3) veratridine, a Na(+) channel opener, enhanced the anoxia-induced Na(+) influx; this could be attenuated by DOR activation; (4) DOR activation did not reduce the anoxia-induced Na(+) influx in the presence of chelerythrine, a broad-spectrum PKC blocker; and (5) DOR effects were blocked by PKCβII peptide inhibitor, and PKCθ pseudosubstrate inhibitor, respectively. We conclude that DOR activation inhibits anoxia-induced Na(+) influx through Na(+) channels via PKC (especially PKCβII and PKCθ isoforms) dependent mechanisms in the cortex. Copyright © 2012 Elsevier Inc. All rights reserved.

  2. Computational and Experimental Investigations of Na-Ion Conduction in Cubic Na 3PSe 4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bo, Shou -Hang; Wang, Yan; Kim, Jae Chul

    All-solid-state Na-ion batteries that operate at or close to room temperature are a promising next-generation battery technology with enhanced safety and reduced manufacturing cost. An indispensable component of this technology is the solid-state electrolyte that allows rapid shuttling of the mobile cation (i.e., Na +) between the cathode and anode. However, there are very few fast Na-ion conductors with ionic conductivity approaching that of the liquid counterparts (i.e., 1 mS cm –1). In this work, we present the synthesis and characterization of a fast Na-ion conductor, cubic Na 3PSe 4. This material possesses a room-temperature ionic conductivity exceeding 0.1 mSmore » cm –1 and does not require high-temperature sintering to minimize grain boundary resistance, making it a promising solid-state electrolyte candidate for all-solid-state Na-ion battery applications. On the basis of density functional theory, nudged elastic band, and molecular dynamics investigations, we demonstrate that the framework of cubic Na 3PSe 4 only permits rapid Na + diffusion with the presence of defects, and that the formation of the Na vacancy (charge-balanced by slight Se 2– oxidation) is more energetically favorable among the various defects considered. This finding provides important guidelines to further improve Na-ion conductivity in this class of materials.« less

  3. Computational and Experimental Investigations of Na-Ion Conduction in Cubic Na 3PSe 4

    DOE PAGES

    Bo, Shou -Hang; Wang, Yan; Kim, Jae Chul; ...

    2015-11-17

    All-solid-state Na-ion batteries that operate at or close to room temperature are a promising next-generation battery technology with enhanced safety and reduced manufacturing cost. An indispensable component of this technology is the solid-state electrolyte that allows rapid shuttling of the mobile cation (i.e., Na +) between the cathode and anode. However, there are very few fast Na-ion conductors with ionic conductivity approaching that of the liquid counterparts (i.e., 1 mS cm –1). In this work, we present the synthesis and characterization of a fast Na-ion conductor, cubic Na 3PSe 4. This material possesses a room-temperature ionic conductivity exceeding 0.1 mSmore » cm –1 and does not require high-temperature sintering to minimize grain boundary resistance, making it a promising solid-state electrolyte candidate for all-solid-state Na-ion battery applications. On the basis of density functional theory, nudged elastic band, and molecular dynamics investigations, we demonstrate that the framework of cubic Na 3PSe 4 only permits rapid Na + diffusion with the presence of defects, and that the formation of the Na vacancy (charge-balanced by slight Se 2– oxidation) is more energetically favorable among the various defects considered. This finding provides important guidelines to further improve Na-ion conductivity in this class of materials.« less

  4. Quasi-solid state rechargeable Na-CO2 batteries with reduced graphene oxide Na anodes.

    PubMed

    Hu, Xiaofei; Li, Zifan; Zhao, Yaran; Sun, Jianchao; Zhao, Qing; Wang, Jianbin; Tao, Zhanliang; Chen, Jun

    2017-02-01

    Na-CO 2 batteries using earth-abundant Na and greenhouse gas CO 2 are promising tools for mobile and stationary energy storage, but they still pose safety risks from leakage of liquid electrolyte and instability of the Na metal anode. These issues result in extremely harsh operating conditions of Na-CO 2 batteries and increase the difficulty of scaling up this technology. We report the development of quasi-solid state Na-CO 2 batteries with high safety using composite polymer electrolyte (CPE) and reduced graphene oxide (rGO) Na anodes. The CPE of PVDF-HFP [poly(vinylidene fluoride- co -hexafluoropropylene)]-4% SiO 2 /NaClO 4 -TEGDME (tetraethylene glycol dimethyl ether) has high ion conductivity (1.0 mS cm -1 ), robust toughness, a nonflammable matrix, and strong electrolyte-locking ability. In addition, the rGO-Na anode presents fast and nondendritic Na + plating/stripping (5.7 to 16.5 mA cm -2 ). The improved kinetics and safety enable the constructed rGO-Na/CPE/CO 2 batteries to successfully cycle in wide CO 2 partial pressure window (5 to 100%, simulated car exhaust) and especially to run for 400 cycles at 500 mA g -1 with a fixed capacity of 1000 mA·hour g -1 in pure CO 2 . Furthermore, we scaled up the reversible capacity to 1.1 A·hour in pouch-type batteries (20 × 20 cm, 10 g, 232 Wh kg -1 ). This study makes quasi-solid state Na-CO 2 batteries an attractive prospect.

  5. Quasi–solid state rechargeable Na-CO2 batteries with reduced graphene oxide Na anodes

    PubMed Central

    Hu, Xiaofei; Li, Zifan; Zhao, Yaran; Sun, Jianchao; Zhao, Qing; Wang, Jianbin; Tao, Zhanliang; Chen, Jun

    2017-01-01

    Na-CO2 batteries using earth-abundant Na and greenhouse gas CO2 are promising tools for mobile and stationary energy storage, but they still pose safety risks from leakage of liquid electrolyte and instability of the Na metal anode. These issues result in extremely harsh operating conditions of Na-CO2 batteries and increase the difficulty of scaling up this technology. We report the development of quasi–solid state Na-CO2 batteries with high safety using composite polymer electrolyte (CPE) and reduced graphene oxide (rGO) Na anodes. The CPE of PVDF-HFP [poly(vinylidene fluoride-co-hexafluoropropylene)]–4% SiO2/NaClO4–TEGDME (tetraethylene glycol dimethyl ether) has high ion conductivity (1.0 mS cm−1), robust toughness, a nonflammable matrix, and strong electrolyte-locking ability. In addition, the rGO-Na anode presents fast and nondendritic Na+ plating/stripping (5.7 to 16.5 mA cm−2). The improved kinetics and safety enable the constructed rGO-Na/CPE/CO2 batteries to successfully cycle in wide CO2 partial pressure window (5 to 100%, simulated car exhaust) and especially to run for 400 cycles at 500 mA g−1 with a fixed capacity of 1000 mA·hour g−1 in pure CO2. Furthermore, we scaled up the reversible capacity to 1.1 A·hour in pouch-type batteries (20 × 20 cm, 10 g, 232 Wh kg−1). This study makes quasi–solid state Na-CO2 batteries an attractive prospect. PMID:28164158

  6. High-resolution molecular-beam spectroscopy of NaCN and Na 13CN

    NASA Astrophysics Data System (ADS)

    van Vaals, J. J.; Meerts, W. Leo; Dymanus, A.

    The sodium cyanide molecule was studied by molecular-beam electric-resonance spectroscopy in the microwave region. We used the seeded-beam technique to produce a supersonic beam with strong translational, rotational and vibrational cooling. In the frequency range 9.5-40 GHz we observed and identified for NaCN 186 and for Na 13CN 107 hyperfine transitions in 20 and 16 rotational transitions, respectively, all in the ground vibrational state. The rotational, the five quartic and three sextic centrifugal distortion constants of NaCN are: A″ = 57921.954(7) MHz; B″ = 8369.312(2) MHz, C″ = 7272.712(2) MHz. All quadrupole and several spin-rotation coupling constants for the hyperfine interaction were evaluated. The quadrupole coupling constants (in MHz) for NaCN are: eQq12(Na) = -5.344(5), eQq12 = 2.397(7). eQq12(N) = 2.148(4), eQq12(N) = -4.142(5). From these constants and those of Na 13CN we have determined the principal components of the quadrupole coupling tensor for potassium and nitrogen. The structure of sodium cyanide evaluated from the rotational constants of NaCN and Na 13CN was found to be T shaped, similar to the structure of KCN but completely different from the linear isocyanide configuration of LiNC. The effective structural parameters for sodium cyanide in the ground vibrational state are: rCN = 1.170(4) Å, rNaC = 2.379(15) Å, rN12N = 2.233(15) Å, in gratifying agreement with ab initio calculations. Both the geometrical structure and the hyperfine coupling justify the conclusion that the CN group in gaseous sodium cyanide approximately can be considered as a free CN - ion.

  7. Synthesis of zeolites Na-A and Na-X from tablet compressed and calcinated coal fly ash

    NASA Astrophysics Data System (ADS)

    Hu, Tao; Gao, Wenyan; Liu, Xin; Zhang, Yifu; Meng, Changgong

    2017-10-01

    Zeolites Na-A and Na-X are important synthetic zeolites widely used for separation and adsorption in industry. It is of great significance to develop energy-efficient routines that can synthesize zeolites Na-A and Na-X from low-cost raw materials. Coal fly ash (CFA) is the major residue from the combustion of coal and biomass containing more than 85% SiO2 and Al2O3, which can readily replace the conventionally used sodium silicate and aluminate for zeolite synthesis. We used Na2CO3 to replace the expensive NaOH used for the calcination of CFA and showed that tablet compression can enhance the contact with Na2CO3 for the activation of CFA through calcination for the synthesis of zeolites Na-A and Na-X under mild conditions. We optimized the control variables for zeolite synthesis and showed that phase-pure zeolite Na-A can be synthesized with CFA at reactant molar ratio, hydrothermal reaction temperature and reaction time of 1.3Na2O: 0.6Al2O3: 1SiO2: 38H2O at 80°C for 6 h, respectively, while phase-pure zeolite Na-X can be synthesized at 2.2Na2O: 0.2Al2O3: 1SiO2: 88H2O at 100°C for 8 h, respectively. The composition, morphology, specific surface area, vibration spectrum and thermogravimetry of synthesized Na-A and Na-X were further characterized.

  8. Structural and Na-ion conduction characteristics of Na 3 PS x Se 4-x

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bo, Shou-Hang; Wang, Yan; Ceder, Gerbrand

    The recent discovery of the isostructrual cubic Na 3PS 4 and Na 3PSe 4 as fast Na-ion conductors provided a general structural framework for the exploration of new sodium superionic conductors. In this work, we systematically investigated the structures and ionic conduction characteristics of a series of compounds with the general chemical formula of Na 3PS xSe 4-x. Synthesis of Na 3PS 4 under different conditions (e.g., temperature, reaction vessel, mass of the precursors) reveals the reactivity of the precursors with the reaction tubes, producing different polymorphs. X-ray diffraction studies on the solid solution phases Na 3PS xSe 4-x more » identified a tetragonal-to-cubic phase transition with increasing Se concentration. This observation is consistent with the computed stability of the tetragonal and cubic polymorphs, where the energy difference between the two polymorphs becomes very close to zero in Se-rich compositions. Furthermore, ab initio molecular dynamic simulations suggest that the fast Na-ion conduction in Na 3PS xSe 4-x may not be causally related with the symmetry or the composition of these phases. The formation of defects, instead, enables fast Na-ion conduction in this class of materials.« less

  9. Formation of Si grains from a NaSi melt prepared by reaction of SiO2 and Na

    NASA Astrophysics Data System (ADS)

    Yamane, Hisanori; Morito, Haruhiko; Uchikoshi, Masahito

    2013-08-01

    A mixture of Na2SiO3 and NaSi was found to be formed by reaction of SiO2 and Na at 650 °C as follows: 5Na+3SiO2→2Na2SiO3+NaSi. Single crystals of NaSi were grown by cooling the mixture of Na2SiO3 and NaSi with an excess amount of Na from 850 °C, and polycrystalline Si was obtained by vaporization of Na from the crystals. Coarse grains of Si were also crystallized by Na evaporation after the formation of Na2SiO3 and Si-dissolved liquid Na at 830 °C. The Si grains were collected by washing the product with water. The yield of the Si grains was 85% of the ideal amount expected from the reaction.

  10. The relative viscosity of NaNO 3 and NaNO 2 aqueous solutions

    DOE PAGES

    Reynolds, Jacob G.; Mauss, Billie M.; Daniel, Richard C.

    2018-05-09

    In aqueous solution, both nitrate and nitrite are planar, monovalent, and have the same elements but different sizes and charge densities. Comparing the viscosity of NaNO 2 and NaNO 3 aqueous solutions provides an opportunity to determine the relative importance of anion size versus strength of anion interaction with water. The viscosity of aqueous NaNO 2 and NaNO 3 were measured over a temperature and concentration range relevant to nuclear waste processing. The viscosity of NaNO 2 solutions was consistently larger than NaNO 3 under all conditions, even though nitrate is larger than nitrite. This was interpreted in terms ofmore » quantum mechanical charge field molecular dynamics calculations that indicate that nitrite forms more and stronger hydrogen bonds with water per oxygen atom than nitrate. Furthermore, these hydrogen bonds inhibit rotational motion required for fluid flow, thus increasing the nitrite solution viscosity relative to that of an equivalent nitrate solution.« less

  11. The relative viscosity of NaNO 3 and NaNO 2 aqueous solutions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reynolds, Jacob G.; Mauss, Billie M.; Daniel, Richard C.

    In aqueous solution, both nitrate and nitrite are planar, monovalent, and have the same elements but different sizes and charge densities. Comparing the viscosity of NaNO 2 and NaNO 3 aqueous solutions provides an opportunity to determine the relative importance of anion size versus strength of anion interaction with water. The viscosity of aqueous NaNO 2 and NaNO 3 were measured over a temperature and concentration range relevant to nuclear waste processing. The viscosity of NaNO 2 solutions was consistently larger than NaNO 3 under all conditions, even though nitrate is larger than nitrite. This was interpreted in terms ofmore » quantum mechanical charge field molecular dynamics calculations that indicate that nitrite forms more and stronger hydrogen bonds with water per oxygen atom than nitrate. Furthermore, these hydrogen bonds inhibit rotational motion required for fluid flow, thus increasing the nitrite solution viscosity relative to that of an equivalent nitrate solution.« less

  12. Croatian Membership in NATO: One of the Crucial Prerequisites for Stabilization of Southeastern Europe

    DTIC Science & Technology

    2002-03-01

    CROATIA – A HISTORICAL OVERVIEW..........................................................15 A. CROATIA UNTIL 1918 ...16 B. CROATIA UNDER SERBIAN DOMINATION 1918 -1991 ......................21 1. World War II...Hungarian Empire, and finally a part of Yugoslavia from 1918 -1991. Despite their lack of independence for a period of almost nine centuries

  13. Na/beta-alumina/NaAlCl4, Cl2/C circulating cell

    NASA Technical Reports Server (NTRS)

    Cherng, Jing-Yih; Bennion, Douglas N.

    1987-01-01

    A study was made of a high specific energy battery based on a sodium negative electrode and a chlorine positive electrode with molten AlCl3-NaCl electrolyte and a solid beta alumina separator. The basic performance of a Na beta-alumina NaAlCl4, Cl2/C circulating cell at 200 C was demonstrated. This cell can be started at 150 C. The use of melting sodium chloroaluminate electrolyte overcomes some of the material problems associated with the high working temperatures of present molten salt systems, such as Na/S and LiAl/FeS, and retains the advantages of high energy density and relatively efficient electrode processes. Preliminary investigations were conducted on a sodium-chlorine static cell, material compability, electrode design, wetting, and theoretical calculations to assure a better chance of success before assembling a Na/Cl2 circulating cell. Mathematical models provide a theoretical explanation for the performance of the NaCl2 battery. The results of mathematical models match the experimental results very well. According to the result of the mathematical modeling, an output at 180 mA/sq cm and 3.2 V can be obtained with optimized cell design.

  14. NA62 and NA48/2 results on search for Heavy Neutral Leptons

    NASA Astrophysics Data System (ADS)

    Lamanna, Gianluca; Aliberti, R.; Ambrosino, F.; Ammendola, R.; Angelucci, B.; Antonelli, A.; Anzivino, G.; Arcidiacono, R.; Barbanera, M.; Biagioni, A.; Bician, L.; Biino, C.; Bizzeti, A.; Blazek, T.; Bloch-Devaux, B.; Bonaiuto, V.; Boretto, M.; Bragadireanu, M.; Britton, D.; Brizioli, F.; Brunetti, M. B.; Bryman, D.; Bucci, F.; Capussela, T.; Ceccucci, A.; Cenci, P.; Cerny, V.; Cerri, C.; Checcucci, B.; Conovaloff, A.; Cooper, P.; Cortina Gil, E.; Corvino, M.; Costantini, F.; Cotta Ramusino, A.; Coward, D.; D'Agostini, G.; Dainton, J.; Dalpiaz, P.; Danielsson, H.; De Simone, N.; Di Filippo, D.; Di Lella, L.; Doble, N.; Dobrich, B.; Duval, F.; Duk, V.; Engelfried, J.; Enik, T.; Estrada-Tristan, N.; Falaleev, V.; Fantechi, R.; Fascianelli, V.; Federici, L.; Fedotov, S.; Filippi, A.; Fiorini, M.; Fry, J.; Fu, J.; Fucci, A.; Fulton, L.; Gamberini, E.; Gatignon, L.; Georgiev, G.; Ghinescu, S.; Gianoli, A.; Giorgi, M.; Giudici, S.; Gonnella, F.; Goudzovski, E.; Graham, C.; Guida, R.; Gushchin, E.; Hahn, F.; Heath, H.; Husek, T.; Hutanu, O.; Hutchcroft, D.; Iacobuzio, L.; Iacopini, E.; Imbergamo, E.; Jenninger, B.; Kampf, K.; Kekelidze, V.; Kholodenko, S.; Khoriauli, G.; Khotyantsev, A.; Kleimenova, A.; Korotkova, A.; Koval, M.; Kozhuharov, V.; Kucerova, Z.; Kudenko, Y.; Kunze, J.; Kurochka, V.; Kurshetsov, V.; Lanfranchi, G.; Lamanna, G.; Latino, G.; Laycock, P.; Lazzeroni, C.; Lenti, M.; Lehmann Miotto, G.; Leonardi, E.; Lichard, P.; Litov, L.; Lollini, R.; Lomidze, D.; Lonardo, A.; Lubrano, P.; Lupi, M.; Lurkin, N.; Madigozhin, D.; Mannelli, I.; Mannocchi, G.; Mapelli, A.; Marchetto, F.; Marchevski, R.; Martellotti, S.; Massarotti, P.; Massri, K.; Maurice, E.; Medvedeva, M.; Mefodev, A.; Menichetti, E.; Migliore, E.; Minucci, E.; Mirra, M.; Misheva, M.; Molokanova, N.; Moulson, M.; Movchan, S.; Napolitano, M.; Neri, I.; Newson, F.; Norton, A.; Noy, M.; Numao, T.; Obraztsov, V.; Ostankov, A.; Padolski, S.; Page, R.; Palladino, V.; Parkinson, C.; Pedreschi, E.; Pepe, M.; Perrin-Terrin, M.; Peruzzo, L.; Petrov, P.; Petrucci, F.; Piandani, R.; Piccini, M.; Pinzino, J.; Polenkevich, I.; Pontisso, L.; Potrebenikov, Yu.; Protopopescu, D.; Raggi, M.; Romano, A.; Rubin, P.; Ruggiero, G.; Ryjov, V.; Salamon, A.; Santoni, C.; Saracino, G.; Sargeni, F.; Semenov, V.; Sergi, A.; Shaikhiev, A.; Shkarovskiy, S.; Soldi, D.; Sougonyaev, V.; Sozzi, M.; Spadaro, T.; Spinella, F.; Sturgess, A.; Swallow, J.; Trilov, S.; Valente, P.; Velghe, B.; Venditti, S.; Vicini, P.; Volpe, R.; Vormstein, M.; Wahl, H.; Wanke, R.; Wrona, B.; Yushchenko, O.; Zamkovsky, M.; Zinchenko, A.

    2018-05-01

    In this paper we present new results on upper limits for the search of Heavy Neutral Leptons (HNL) with data collected by NA48/2 (2003-2004), NA62-RK (2007) and NA62 (2015) CERN experiments. The data collected with different trigger configuration allow to search for both long and short living heavy neutrinos in the mass range below the kaon mass. In addition the status of the search for K+ → π+vv with the NA62 detector will be briefly presented.

  15. Physiological responses to salt stress of salt-adapted and directly salt (NaCl and NaCl+Na2SO4 mixture)-stressed cyanobacterium Anabaena fertilissima.

    PubMed

    Swapnil, Prashant; Rai, Ashwani K

    2018-05-01

    Soil salinity in nature is generally mixed type; however, most of the studies on salt toxicity are performed with NaCl and little is known about sulfur type of salinity (Na 2 SO 4 ). Present study discerns the physiologic mechanisms responsible for salt tolerance in salt-adapted Anabaena fertilissima, and responses of directly stressed parent cells to NaCl and NaCl+Na 2 SO 4 mixture. NaCl at 500 mM was lethal to the cyanobacterium, whereas salt-adapted cells grew luxuriantly. Salinity impaired gross photosynthesis, electron transport activities, and respiration in parent cells, but not in the salt-adapted cells, except a marginal increase in PSI activity. Despite higher Na + concentration in the salt mixture, equimolar NaCl appeared more inhibitive to growth. Sucrose and trehalose content and antioxidant activities were maximal in 250 mM NaCl-treated cells, followed by salt mixture and was almost identical in salt-adapted (exposed to 500 mm NaCl) and control cells, except a marginal increase in ascorbate peroxidase activity and an additional fourth superoxide dismutase isoform. Catalase isoform of 63 kDa was induced only in salt-stressed cells. Salinity increased the uptake of intracellular Na + and Ca 2+ and leakage of K + in parent cells, while cation level in salt-adapted cells was comparable to control. Though there was differential increase in intracellular Ca 2+ under different salt treatments, ratio of Ca 2+ /Na + remained the same. It is inferred that stepwise increment in the salt concentration enabled the cyanobacterium to undergo priming effect and acquire robust and efficient defense system involving the least energy.

  16. Vacancy-Controlled Na+ Superion Conduction in Na11 Sn2 PS12.

    PubMed

    Duchardt, Marc; Ruschewitz, Uwe; Adams, Stefan; Dehnen, Stefanie; Roling, Bernhard

    2018-01-26

    Highly conductive solid electrolytes are crucial to the development of efficient all-solid-state batteries. Meanwhile, the ion conductivities of lithium solid electrolytes match those of liquid electrolytes used in commercial Li + ion batteries. However, concerns about the future availability and the price of lithium made Na + ion conductors come into the spotlight in recent years. Here we present the superionic conductor Na 11 Sn 2 PS 12 , which possesses a room temperature Na + conductivity close to 4 mS cm -1 , thus the highest value known to date for sulfide-based solids. Structure determination based on synchrotron X-ray powder diffraction data proves the existence of Na + vacancies. As confirmed by bond valence site energy calculations, the vacancies interconnect ion migration pathways in a 3D manner, hence enabling high Na + conductivity. The results indicate that sodium electrolytes are about to equal the performance of their lithium counterparts. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Experimental and first-principles study of photoluminescent and optical properties of Na-doped CuAlO2: the role of the NaAl-2Na i complex

    NASA Astrophysics Data System (ADS)

    Liu, Ruijian; Li, Yongfeng; Yao, Bin; Ding, Zhanhui; Deng, Rui; Zhang, Ligong; Zhao, Haifeng; Liu, Lei

    2015-08-01

    We report that a band-tail emission at 3.08 eV, lower than near-band-edge energy, is observed in photoluminescence measurements of bulk Na-doped CuAlO2. The band-tail emission is attributed to Na-related defects. Electronic structure calculations based on the first-principles method demonstrate that the donor-acceptor compensated complex of NaAl-2Na i in Na-doped CuAlO2 plays a key role in leading to the band-tail emission and bandgap narrowing. Furthermore, Hall effect measurements indicates that the hole concentration in CuAlO2 is independent on Na doping, which is well understood by the donor-acceptor compensation effect of NaAl-2Na i complex.

  18. Reconstructing Harry: A Genealogical Study of a Colonial Family ‘Inside’ and ‘Outside’ the Grahamstown Asylum, 1888–1918

    PubMed Central

    Wilbraham, Lindy

    2014-01-01

    Recent scholarship has explored the dynamics between families and colonial lunatic asylums in the late nineteenth century, where families actively participated in the processes of custodial care, committal, treatment and release of their relatives. This paper works in this historical field, but with some methodological and theoretical differences. The Foucauldian study is anchored to a single case and family as an illness narrative that moves cross-referentially between bureaucratic state archival material, psychiatric case records, and intergenerational family-storytelling and family photographs. Following headaches and seizures, Harry Walter Wilbraham was medically boarded from his position as Postmaster in the Cape of Good Hope Colony of South Africa with a ‘permanent disease of the brain’, and was committed to the Grahamstown Asylum in 1910, where he died the following year, aged 40 years. In contrast to writings about colonial asylums that usually describe several patient cases and thematic patterns in archival material over time and place, this study’s genealogical lens examines one white settler male patient’s experiences within mental health care in South Africa between 1908 and 1911. The construction of Harry’s ‘case’ interweaves archival sources and reminiscences inside and outside the asylum, and places it within psychiatric discourse of the time, and family dynamics in the years that followed. Thus, this case study maps the constitution of ‘patient’ and ‘family’ in colonial life, c.1888–1918, and considers the calamity, uncertainty, stigma and silences of mental illness. PMID:24775428

  19. 17 CFR 239.24 - Form N-5, form for registration of small business investment company under the Securities Act of...

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... registration of small business investment company under the Securities Act of 1933 and the Investment Company... N-5, form for registration of small business investment company under the Securities Act of 1933 and... of 1933 of securities issued by any small business investment company which is registered under the...

  20. Structural and Na-ion conduction characteristics of Na 3PS xSe 4–x

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bo, Shou -Hang; Wang, Yan; Ceder, Gerbrand

    The recent discovery of the isostructrual cubic Na 3PS 4 and Na 3PSe 4 as fast Na-ion conductors provided a general structural framework for the exploration of new sodium superionic conductors. In this work, we systematically investigated the structures and ionic conduction characteristics of a series of compounds with the general chemical formula of Na 3PS xSe 4–x. Synthesis of Na 3PS 4 under different conditions (e.g., temperature, reaction vessel, mass of the precursors) reveals the reactivity of the precursors with the reaction tubes, producing different polymorphs. X-ray diffraction studies on the solid solution phases Na 3PS xSe 4–x identifiedmore » a tetragonal-to-cubic phase transition with increasing Se concentration. This observation is consistent with the computed stability of the tetragonal and cubic polymorphs, where the energy difference between the two polymorphs becomes very close to zero in Se-rich compositions. Furthermore, ab initio molecular dynamic simulations suggest that the fast Na-ion conduction in Na 3PS xSe 4–x may not be causally related with the symmetry or the composition of these phases. The formation of defects, instead, enables fast Na-ion conduction in this class of materials.« less

  1. Structural and Na-ion conduction characteristics of Na 3PS xSe 4–x

    DOE PAGES

    Bo, Shou -Hang; Wang, Yan; Ceder, Gerbrand

    2016-05-19

    The recent discovery of the isostructrual cubic Na 3PS 4 and Na 3PSe 4 as fast Na-ion conductors provided a general structural framework for the exploration of new sodium superionic conductors. In this work, we systematically investigated the structures and ionic conduction characteristics of a series of compounds with the general chemical formula of Na 3PS xSe 4–x. Synthesis of Na 3PS 4 under different conditions (e.g., temperature, reaction vessel, mass of the precursors) reveals the reactivity of the precursors with the reaction tubes, producing different polymorphs. X-ray diffraction studies on the solid solution phases Na 3PS xSe 4–x identifiedmore » a tetragonal-to-cubic phase transition with increasing Se concentration. This observation is consistent with the computed stability of the tetragonal and cubic polymorphs, where the energy difference between the two polymorphs becomes very close to zero in Se-rich compositions. Furthermore, ab initio molecular dynamic simulations suggest that the fast Na-ion conduction in Na 3PS xSe 4–x may not be causally related with the symmetry or the composition of these phases. The formation of defects, instead, enables fast Na-ion conduction in this class of materials.« less

  2. [The health policy of the "Council of the People's Representatives": the German revolution 1918/1919 in medical historical perspective II: health policy as a factor of continuity and stability].

    PubMed

    Kratzsch, Tilman

    2005-01-01

    Most important for the events at the turn of 1918/19 was the coincidence of the revolution and the end of the war. This meant that in a very short time the troops had to be withdrawn from the front, the size of the army had to be reduced, and the wartime economy had to be transformed into a peace economy. Apart from the resulting economical and social problems, military demobilisation was closely linked with medical and health political difficulties. The revolutionary government saw itself as a provisional arrangement to ensure the unity of the state and the functioning of the German Reich. The maintenance of medical care and provision of a minimum of foodstuffs made health policy important during the months of revolution. Despite a positive balance of payments and a "health policy of continuity", the revolutionary government was unable to win the medical profession for its aims, because it failed to dispel suspicions that the medical profession was going to be socialised.

  3. The U.S. Air Service in World War I. Volume IV. Postwar Review,

    DTIC Science & Technology

    1979-01-01

    19, 1914 12 M 10 No 1)iinag S-ept. 10, 1416 2 P)ITt is Nil Dama~e Aug 13, 1918H 1145 pmn 16 D~ouble track dietruyrd, 17 hours to rCliAtt St2516, 1918 ...this use of its bombing aviation) as carried out in the war of 1914 - 1918 is the lack of a predetermined program carefully calculated to destroy by...History," R-I, the correction Stuttgart, with munition works (23 August 1914 to 26 being the addition of the at Oberndorf as the alternate September 1918

  4. A thermochemical explanation for the stability of NaCl3 and NaCl7

    NASA Astrophysics Data System (ADS)

    Fernandes de Farias, Robson

    2017-03-01

    Thermodynamically stable cubic and orthorhombic NaCl3 as well as NaCl7 have been synthesized (Zhang et al., 2013). In the present work, a thermochemical explanation for the stability of such unusual sodium chlorides is provided, based on lattice energy values. Using the Glasser-Jenkins generalized equation (Glasser and Jenkins, 2000) lattice energies (kJ mol-1) of -162.5, -168.9 and -113.1 are calculated for Pm3n NaCl3, Pnma NaCl3 and NaCl7, respectively. It is postulated that any NaxCly compound could be synthesized, if the ionic character of the Nasbnd Cl bond in the prepared compound remains around 80%, and the sodium charge below unit.

  5. The Perfect Sturm: Innovation and the Origins of Blitzkrieg in World War I

    DTIC Science & Technology

    2006-12-01

    attempt similar offensives in 1918 on the Western Front in France. Initially successful, the offensives later stalled. However, the lessons of these...Italian defeat. This success encouraged the German leadership to attempt similar offensives in 1918 on the Western Front in France. Initially...77 2. Isonzo Front 1915 – 1918 : ..................................................... 78 3

  6. Long range intermolecular interactions between the alkali diatomics Na2, K2, and NaK

    NASA Astrophysics Data System (ADS)

    Zemke, Warren T.; Byrd, Jason N.; Michels, H. Harvey; Montgomery, John A.; Stwalley, William C.

    2010-06-01

    Long range interactions between the ground state alkali diatomics Na2-Na2, K2-K2, Na2-K2, and NaK-NaK are examined. Interaction energies are first determined from ab initio calculations at the coupled-cluster with singles, doubles, and perturbative triples [CCSD(T)] level of theory, including counterpoise corrections. Long range energies calculated from diatomic molecular properties (polarizabilities and dipole and quadrupole moments) are then compared with the ab initio energies. A simple asymptotic model potential ELR=Eelec+Edisp+Eind is shown to accurately represent the intermolecular interactions for these systems at long range.

  7. Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps

    PubMed Central

    Vedovato, Natascia

    2014-01-01

    A single Na+/K+-ATPase pumps three Na+ outwards and two K+ inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na+ than K+ generates outward current across the cell membrane. Less well understood is the ability of Na+/K+ pumps to generate an inward current of protons. Originally noted in pumps deprived of external K+ and Na+ ions, as inward current at negative membrane potentials that becomes amplified when external pH is lowered, this proton current is generally viewed as an artifact of those unnatural conditions. We demonstrate here that this inward current also flows at physiological K+ and Na+ concentrations. We show that protons exploit ready reversibility of conformational changes associated with extracellular Na+ release from phosphorylated Na+/K+ pumps. Reversal of a subset of these transitions allows an extracellular proton to bind an acidic side chain and to be subsequently released to the cytoplasm. This back-step of phosphorylated Na+/K+ pumps that enables proton import is not required for completion of the 3 Na+/2 K+ transport cycle. However, the back-step occurs readily during Na+/K+ transport when external K+ ion binding and occlusion are delayed, and it occurs more frequently when lowered extracellular pH raises the probability of protonation of the externally accessible carboxylate side chain. The proton route passes through the Na+-selective binding site III and is distinct from the principal pathway traversed by the majority of transported Na+ and K+ ions that passes through binding site II. The inferred occurrence of Na+/K+ exchange and H+ import during the same conformational cycle of a single molecule identifies the Na+/K+ pump as a hybrid transporter. Whether Na+/K+ pump–mediated proton inflow may have any physiological or pathophysiological significance remains to be clarified. PMID

  8. A Solution to Moldova’s Transdniestrian Conflict: Regional Complex Interdependence

    DTIC Science & Technology

    2003-06-01

    16 a. Reunion with Romania in 1918 and the Transdniestrian Factor...Russia (Soviet Union) and Romania for Bessarabia (MSSR), when Transdniestria was used as a psychological check factor. a. Reunion with Romania in 1918 ...fate of Bessarabia, resulting in unification with Romania in 1918 . However, that unification was not a welcome outcome for Bessarabians but rather

  9. Long range intermolecular interactions between the alkali diatomics Na(2), K(2), and NaK.

    PubMed

    Zemke, Warren T; Byrd, Jason N; Michels, H Harvey; Montgomery, John A; Stwalley, William C

    2010-06-28

    Long range interactions between the ground state alkali diatomics Na(2)-Na(2), K(2)-K(2), Na(2)-K(2), and NaK-NaK are examined. Interaction energies are first determined from ab initio calculations at the coupled-cluster with singles, doubles, and perturbative triples [CCSD(T)] level of theory, including counterpoise corrections. Long range energies calculated from diatomic molecular properties (polarizabilities and dipole and quadrupole moments) are then compared with the ab initio energies. A simple asymptotic model potential E(LR)=E(elec)+E(disp)+E(ind) is shown to accurately represent the intermolecular interactions for these systems at long range.

  10. Effect of NaNO3 concentration on anodic electrochemical behavior on the Sb surface in NaOH solution

    NASA Astrophysics Data System (ADS)

    He, Yun-long; Xu, Rui-dong; He, Shi-wei; Chen, Han-sen; Li, Kuo; Zhu, Yun; Shen, Qing-feng

    2018-03-01

    The effect of NaNO3 concentration on the anodic electrochemical behavior of antimony in 4 M NaOH solution was investigated using cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) analyses. The mechanism of NO 3 - concentration effect on the anodic electrochemical behavior of antimony was proposed, and its availability was confirmed by experimental results. The effect of NaNO3 on the anodic behavior of antimony in NaOH solution can be interpreted as a stepwise formation of different antimony compounds with different NaNO3 concentrations. Metallic antimony is apt to be oxidized into Sb2O3 within the NaNO3 concentration range of 0-0.48 M. NaSbO3 can be found on the antimony surface when the NaNO3 concentration increases gradually. Insoluable NaSbO3 inhibits the anodic oxidation of antimony due to its shielding effect on the mass transport of the reactants and products. Surface morphology and composition were analyzed by X-ray photoelectron spectroscopy (XPS), scanning electronic microscopy (SEM), and electron dispersion spectroscopy (EDS) analyses. Results indicate that the anodic oxidation layer is composed of Sb2O3, NaSbO3, and Sb. The atomic proportion of antimony in the form of NaSbO3 increases with increasing NaNO3 concentration due to the powerful oxidizing property of NaNO3.

  11. Precursor Routes to Complex Ternary Intermetallics: Single-Crystal and Microcrystalline Preparation of Clathrate-I Na8Al8Si38 from NaSi + NaAlSi.

    PubMed

    Dong, Yongkwan; Chai, Ping; Beekman, Matt; Zeng, Xiaoyu; Tritt, Terry M; Nolas, George S

    2015-06-01

    Single crystals of the ternary clathrate-I Na8Al8Si38 were synthesized by kinetically controlled thermal decomposition (KCTD), and microcrystalline Na8Al8Si38 was synthesized by spark plasma sintering (SPS) using a NaSi + NaAlSi mixture as the precursor. Na8AlxSi46-x compositions with x ≤ 8 were also synthesized by SPS from precursor mixtures of different ratios. The crystal structure of Na8Al8Si38 was investigated using both Rietveld and single-crystal refinements. Temperature-dependent transport and UV/vis measurements were employed in the characterization of Na8Al8Si38, with diffuse-reflectance measurement indicating an indirect optical gap of 0.64 eV. Our results indicate that, when more than one precursor is used, both SPS and KCTD are effective methods for the synthesis of multinary inorganic phases that are not easily accessible by traditional solid-state synthesis or crystal growth techniques.

  12. On the Stability of NaO2 in Na-O2 Batteries.

    PubMed

    Liu, Chenjuan; Carboni, Marco; Brant, William R; Pan, Ruijun; Hedman, Jonas; Zhu, Jiefang; Gustafsson, Torbjörn; Younesi, Reza

    2018-04-25

    Na-O 2 batteries are regarded as promising candidates for energy storage. They have higher energy efficiency, rate capability, and chemical reversibility than Li-O 2 batteries; in addition, sodium is cheaper and more abundant compared to lithium. However, inconsistent observations and instability of discharge products have inhibited the understanding of the working mechanism of this technology. In this work, we have investigated a number of factors that influence the stability of the discharge products. By means of in operando powder X-ray diffraction study, the influence of oxygen, sodium anode, salt, solvent, and carbon cathode were investigated. The Na metal anode and an ether-based solvent are the main factors that lead to the instability and decomposition of NaO 2 in the cell environment. This fundamental insight brings new information on the working mechanism of Na-O 2 batteries.

  13. Na+/H+ and Na+/NH4+ exchange activities of zebrafish NHE3b expressed in Xenopus oocytes

    PubMed Central

    Ito, Yusuke; Kato, Akira; Hirata, Taku; Hirose, Shigehisa

    2014-01-01

    Zebrafish Na+/H+ exchanger 3b (zNHE3b) is highly expressed in the apical membrane of ionocytes where Na+ is absorbed from ion-poor fresh water against a concentration gradient. Much in vivo data indicated that zNHE3b is involved in Na+ absorption but not leakage. However, zNHE3b-mediated Na+ absorption has not been thermodynamically explained, and zNHE3b activity has not been measured. To address this issue, we overexpressed zNHE3b in Xenopus oocytes and characterized its activity by electrophysiology. Exposure of zNHE3b oocytes to Na+-free media resulted in significant decrease in intracellular pH (pHi) and intracellular Na+ activity (aNai). aNai increased significantly when the cytoplasm was acidified by media containing CO2-HCO3− or butyrate. Activity of zNHE3b was inhibited by amiloride or 5-ethylisopropyl amiloride (EIPA). Although the activity was accompanied by a large hyperpolarization of ∼50 mV, voltage-clamp experiments showed that Na+/H+ exchange activity of zNHE3b is electroneutral. Exposure of zNHE3b oocytes to medium containing NH3/NH4+ resulted in significant decreases in pHi and aNai and significant increase in intracellular NH4+ activity, indicating that zNHE3b mediates the Na+/NH4+ exchange. In low-Na+ (0.5 mM) media, zNHE3b oocytes maintained aNai of 1.3 mM, and Na+-influx was observed when pHi was decreased by media containing CO2-HCO3− or butyrate. These results provide thermodynamic evidence that zNHE3b mediates Na+ absorption from ion-poor fresh water by its Na+/H+ and Na+/NH4+ exchange activities. PMID:24401990

  14. Shoot Na+ exclusion and increased salinity tolerance engineered by cell type-specific alteration of Na+ transport in Arabidopsis.

    PubMed

    Møller, Inge S; Gilliham, Matthew; Jha, Deepa; Mayo, Gwenda M; Roy, Stuart J; Coates, Juliet C; Haseloff, Jim; Tester, Mark

    2009-07-01

    Soil salinity affects large areas of cultivated land, causing significant reductions in crop yield globally. The Na+ toxicity of many crop plants is correlated with overaccumulation of Na+ in the shoot. We have previously suggested that the engineering of Na+ exclusion from the shoot could be achieved through an alteration of plasma membrane Na+ transport processes in the root, if these alterations were cell type specific. Here, it is shown that expression of the Na+ transporter HKT1;1 in the mature root stele of Arabidopsis thaliana decreases Na+ accumulation in the shoot by 37 to 64%. The expression of HKT1;1 specifically in the mature root stele is achieved using an enhancer trap expression system for specific and strong overexpression. The effect in the shoot is caused by the increased influx, mediated by HKT1;1, of Na+ into stelar root cells, which is demonstrated in planta and leads to a reduction of root-to-shoot transfer of Na+. Plants with reduced shoot Na+ also have increased salinity tolerance. By contrast, plants constitutively expressing HKT1;1 driven by the cauliflower mosaic virus 35S promoter accumulated high shoot Na+ and grew poorly. Our results demonstrate that the modification of a specific Na+ transport process in specific cell types can reduce shoot Na+ accumulation, an important component of salinity tolerance of many higher plants.

  15. Ecotoxicological evaluation of three deicers (NaCl, NaFo, CMA)-effect on terrestrial organisms.

    PubMed

    Robidoux, P Y; Delisle, C E

    2001-02-01

    The use of chemical deicers such as sodium chloride (NaCl) has increased significantly during the past three decades. Deicers induce metal corrosion and alter the physicochemical properties of soils and water. Environmental damage caused by the use of NaCl has prompted government agencies to find alternative deicers. This article presents a comparative ecotoxicological study of three deicers on soil organisms. Sodium formiate (NaFo) and calcium-magnesium acetate (CMA) are the most interesting commercially available deicers based upon their characteristics and potential toxicity. Organisms used in this study were four species of macrophytes (cress (Lepidium sativum), barley (Ordeum vulgare), red fescue grass (Festuca rubra), Kentucky bluegrass (Poa pratensis)) and an invertebrate (Eisenia fetida). Using standardized and modified methods, the relative toxicity of deicers was CMA < NaFo congruent with NaCl. The results demonstrate that these chemicals could have similar impacts in terrestrial environments since similar quantities of NaFo and greater amounts of CMA are necessary to achieve the same efficiency as NaCl. The toxicity of the tested substances was lower in natural composted soil than in artificial substrate (silica or OECD soil), indicating decreased environmental bioavailability. The response of the organisms changed according to endpoint, species, and soil characteristics (artificial substrate as compared to natural organic soil). The most sensitive endpoint measured was macrophyte growth with Kentucky bluegrass being the most sensitive species. Copyright 2001 Academic Press.

  16. Effects of non-uniform root zone salinity on water use, Na+ recirculation, and Na+ and H+ flux in cotton

    PubMed Central

    Kong, Xiangqiang; Luo, Zhen; Dong, Hezhong; Eneji, A. Egrinya

    2012-01-01

    A new split-root system was established through grafting to study cotton response to non-uniform salinity. Each root half was treated with either uniform (100/100 mM) or non-uniform NaCl concentrations (0/200 and 50/150 mM). In contrast to uniform control, non-uniform salinity treatment improved plant growth and water use, with more water absorbed from the non- and low salinity side. Non-uniform treatments decreased Na+ concentrations in leaves. The [Na+] in the ‘0’ side roots of the 0/200 treatment was significantly higher than that in either side of the 0/0 control, but greatly decreased when the ‘0’ side phloem was girdled, suggesting that the increased [Na+] in the ‘0’ side roots was possibly due to transportation of foliar Na+ to roots through phloem. Plants under non-uniform salinity extruded more Na+ from the root than those under uniform salinity. Root Na+ efflux in the low salinity side was greatly enhanced by the higher salinity side. NaCl-induced Na+ efflux and H+ influx were inhibited by amiloride and sodium orthovanadate, suggesting that root Na+ extrusion was probably due to active Na+/H+ antiport across the plasma membrane. Improved plant growth under non-uniform salinity was thus attributed to increased water use, reduced leaf Na+ concentration, transport of excessive foliar Na+ to the low salinity side, and enhanced Na+ efflux from the low salinity root. PMID:22200663

  17. Temperature-dependent formation of NaCl dihydrate in levitated NaCl and sea salt aerosol particles.

    PubMed

    Peckhaus, Andreas; Kiselev, Alexei; Wagner, Robert; Duft, Denis; Leisner, Thomas

    2016-12-28

    Recent laboratory studies indicate that the hydrated form of crystalline NaCl is potentially important for atmospheric processes involving depositional ice nucleation on NaCl dihydrate particles under cirrus cloud conditions. However, recent experimental studies reported a strong discrepancy between the temperature intervals where the efflorescence of NaCl dihydrate has been observed. Here we report the measurements of the volume specific nucleation rate of crystalline NaCl in the aqueous solution droplets of pure NaCl suspended in an electrodynamic balance at constant temperature and humidity in the range from 250 K to 241 K. Based on these measurements, we derive the interfacial energy of crystalline NaCl dihydrate in a supersaturated NaCl solution and determined its temperature dependence. Taking into account both temperature and concentration dependence of nucleation rate coefficients, we explain the difference in the observed fractions of NaCl dihydrate reported in the previous studies. Applying the heterogeneous classical nucleation theory model, we have been able to reproduce the 5 K shift of the NaCl dihydrate efflorescence curve observed for the sea salt aerosol particles, assuming the presence of super-micron solid inclusions (hypothetically gypsum or hemihydrate of CaSO 4 ). These results support the notion that the phase transitions in microscopic droplets of supersaturated solution should be interpreted by accounting for the stochastic nature of homogeneous and heterogeneous nucleation and cannot be understood on the ground of bulk phase diagrams alone.

  18. Temperature-dependent formation of NaCl dihydrate in levitated NaCl and sea salt aerosol particles

    NASA Astrophysics Data System (ADS)

    Peckhaus, Andreas; Kiselev, Alexei; Wagner, Robert; Duft, Denis; Leisner, Thomas

    2016-12-01

    Recent laboratory studies indicate that the hydrated form of crystalline NaCl is potentially important for atmospheric processes involving depositional ice nucleation on NaCl dihydrate particles under cirrus cloud conditions. However, recent experimental studies reported a strong discrepancy between the temperature intervals where the efflorescence of NaCl dihydrate has been observed. Here we report the measurements of the volume specific nucleation rate of crystalline NaCl in the aqueous solution droplets of pure NaCl suspended in an electrodynamic balance at constant temperature and humidity in the range from 250 K to 241 K. Based on these measurements, we derive the interfacial energy of crystalline NaCl dihydrate in a supersaturated NaCl solution and determined its temperature dependence. Taking into account both temperature and concentration dependence of nucleation rate coefficients, we explain the difference in the observed fractions of NaCl dihydrate reported in the previous studies. Applying the heterogeneous classical nucleation theory model, we have been able to reproduce the 5 K shift of the NaCl dihydrate efflorescence curve observed for the sea salt aerosol particles, assuming the presence of super-micron solid inclusions (hypothetically gypsum or hemihydrate of CaSO4). These results support the notion that the phase transitions in microscopic droplets of supersaturated solution should be interpreted by accounting for the stochastic nature of homogeneous and heterogeneous nucleation and cannot be understood on the ground of bulk phase diagrams alone.

  19. Scintillation efficiency measurement of Na recoils in NaI(Tl) below the DAMA/LIBRA energy threshold

    NASA Astrophysics Data System (ADS)

    Xu, Jingke; Shields, Emily; Calaprice, Frank; Westerdale, Shawn; Froborg, Francis; Suerfu, Burkhant; Alexander, Thomas; Aprahamian, Ani; Back, Henning O.; Casarella, Clark; Fang, Xiao; Gupta, Yogesh K.; Ianni, Aldo; Lamere, Edward; Lippincott, W. Hugh; Liu, Qian; Lyons, Stephanie; Siegl, Kevin; Smith, Mallory; Tan, Wanpeng; Kolk, Bryant Vande

    2015-07-01

    The dark matter interpretation of the DAMA modulation signal depends on the NaI(Tl) scintillation efficiency of nuclear recoils. Previous measurements for Na recoils have large discrepancies, especially in the DAMA/LIBRA modulation energy region. We report a quenching effect measurement of Na recoils in NaI(Tl) from 3 to 52 keVnr, covering the whole DAMA/LIBRA energy region for dark matter-Na scattering interpretations. By using a low-energy, pulsed neutron beam, a double time-of-flight technique, and pulse-shape discrimination methods, we obtained the most accurate measurement of this kind for NaI(Tl) to date. The results differ significantly from the DAMA reported values at low energies but fall between the other previous measurements. We present the implications of the new quenching results for the dark matter interpretation of the DAMA modulation signal.

  20. Dynamic polarizabilities and Van der Waals coefficients for alkali atoms Li, Na and alkali dimer molecules Li2, Na2 and NaLi

    NASA Astrophysics Data System (ADS)

    Mérawa, M.; Dargelos, A.

    1998-07-01

    The present paper gives an account of investigations of the polarizability of the alkali atoms Li, Na, diatomics homonuclear and heteronuclear Li2, Na2 and NaLi at SCF (Self Consistent Field) level of approximation and at correlated level, using a time Time-Dependent Gauge Invariant method (TDGI). Our static polarizability values agree with the best experimental and theoretical determinations. The Van der Waals C6 coefficients for the atom-atom, atom-dimer and dimer-dimer interactions have been evaluated. Les polarisabilités des atomes alcalins Li, Na, et des molécules diatomiques homonucléaires et hétéronucléaire Li2, Na2 et NaLi, ont été calculées au niveau SCF (Self Consistent Field) et au niveau corrélé à partir d'une méthode invariante de jauge dépendante du temps(TDGI). Nos valeurs des polarisabilités statiques sont en accord avec les meilleurs déterminations expérimentales et théoriques. Les coefficients C6 de Van de Waals pour les interactions atome-atome, atome-dimère et dimère-dimère ont également été évalués.

  1. Studies of Inelastic Collisions of NaK and NaCs Molecules with Atomic Perturbers

    NASA Astrophysics Data System (ADS)

    Jones, Joshua A.

    We have investigated collisions of NaK molecules in the first excited state [2(A)1Sigma+], with Ar and He collision partners using laser-induced fluorescence spectroscopy (LIF) and polarization-labeling (PL) spectroscopy in a two-step excitation scheme. Additionally, we have investigated collisions of NaCs molecules in the first excited state [2(A)1Sigma +] with Ar and He perturbers using the LIF technique. We use a pump-probe, two-step excitation process. The pump laser prepares the molecule in a particular ro-vibrational (v, J) level in the A state. The probe laser frequency is scanned over transitions to the 31Π in NaK or to the 53Π in NaCs. In addition to observing strong direct lines, we also see weak collisional satellite lines that arise from collisions in the intermediate state that take the molecule from the prepared level (v, J) to level (v, J + Delta J). The ratio of the intensity of the collisional line to the intensity of the direct line in LIF and PL yield information about population and orientation transfer. Our results show a propensity for DeltaJ=even collisions of NaK with Ar and an even stronger propensity for collisions with He. Collisions of NaCs with Ar do not show any such J=even propensity. Preliminary investigations of collisions of NaCs with He seem to indicate a slight J=even propensity. In addition, we observe that rotationally inelastic collisions of excited NaK molecules with potassium atoms destroy almost all of the orientation, while collisions with argon destroy about one third to two thirds and collisions with helium destroy only about zero to one third of the initial orientation.

  2. Scintillation efficiency measurement of Na recoils in NaI(Tl) below the DAMA/LIBRA energy threshold

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Xu, Jingke; Shields, Emily; Calaprice, Frank

    2015-07-01

    The dark matter interpretation of the DAMA modulation signal depends on the NaI(Tl) scintillation efficiency of nuclear recoils. Previous measurements for Na recoils have large discrepancies, especially in the DAMA/LIBRA modulation energy region. We report a quenching effect measurement of Na recoils in NaI(Tl) from 3 to 52 keVnr, covering the whole DAMA/LIBRA energy region for dark matter-Na scattering interpretations. By using a low-energy, pulsed neutron beam, a double time-of-flight technique, and pulse-shape discrimination methods, we obtained the most accurate measurement of this kind for NaI(Tl) to date. The results differ significantly from the DAMA reported values at low energies butmore » fall between the other previous measurements. We present the implications of the new quenching results for the dark matter interpretation of the DAMA modulation signal.« less

  3. Studies of rotationally inelastic collisions of NaK and NaCs with Ar and He perturbers

    NASA Astrophysics Data System (ADS)

    Jones, J.; Faust, C.; Richter, K.; Wolfe, C. M.; Ashman, S.; Malenda, R. F.; Weiser, P.; Carlus, S.; Fragale, A.; Hickman, A. P.; Huennekens, J.

    2013-05-01

    We report studies of rotationally inelastic collisions of Ar and He atoms with the molecules NaK and NaCs prepared in various ro-vibrational levels of the A1Σ+ electronic state. We use laser induced fluorescence (LIF) and polarization labeling (PL) spectroscopy in a pump-probe, two step excitation process. The pump excites the molecule to a ro-vibrational level (v , J) in the A state. The probe laser is scanned over transitions to the 31 Π state in NaK or the 53 Π state in NaCs. In addition to strong direct lines, we observe weak satellite lines that arise from collision-induced transitions of the A state level (v , J) to (v , J + ΔJ) . The ratio of intensities of the satellite line to the direct line in LIF and PL yields information about population and orientation transfer. Preliminary results show a strong propensity for collisions with ΔJ =even for NaK; the propensity is larger for He than for Ar. Collisions of NaCs with He show a similar propensity, but collisions of NaCs with Ar do not. Theoretical calculations are also underway. For He-NaK, we have completed potential surface calculations using GAMESS and coupled channel scattering calculations of rotational energy transfer and transfer of orientation. Work supported by NSF and XSEDE.

  4. Clues to NaCN formation

    NASA Astrophysics Data System (ADS)

    Quintana-Lacaci, G.; Cernicharo, J.; Velilla Prieto, L.; Agúndez, M.; Castro-Carrizo, A.; Fonfría, J. P.; Massalkhi, S.; Pardo, J. R.

    2017-11-01

    Context. ALMA is providing us essential information on where certain molecules form. Observing where these molecules emission arises from, the physical conditions of the gas, and how this relates with the presence of other species allows us to understand the formation of many species, and to significantly improve our knowledge of the chemistry that occurs in the space. Aims: We studied the molecular distribution of NaCN around IRC +10216, a molecule detected previously, but whose origin is not clear. High angular resolution maps allow us to model the abundance distribution of this molecule and check suggested formation paths. Methods: We modeled the emission of NaCN assuming local thermal equilibrium (LTE) conditions. These profiles were fitted to azimuthal averaged intensity profiles to obtain an abundance distribution of NaCN. Results: We found that the presence of NaCN seems compatible with the presence of CN, probably as a result of the photodissociation of HCN, in the inner layers of the ejecta of IRC +10216. However, similar as for CH3CN, current photochemical models fail to reproduce this CN reservoir. We also found that the abundance peak of NaCN appears at a radius of 3 × 1015 cm, approximately where the abundance of NaCl, suggested to be the parent species, starts to decay. However, the abundance ratio shows that the NaCl abundance is lower than that obtained for NaCN. We expect that the LTE assumption might result in NaCN abundances higher than the real ones. Updated photochemical models, collisional rates, and reaction rates are essential to determine the possible paths of the NaCN formation. Based on observations carried out with ALMA and the IRAM 30 m Telescope. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada) and NSC and ASIAA (Taiwan), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. IRAM is supported by INSU/CNRS (France

  5. Study on Na layer response to geomagnetic activities based on Odin/OSIRIS Na density data

    NASA Astrophysics Data System (ADS)

    Tsuda, Takuo; Nakamura, Takuji; Hedin, Jonas; Gumbel, Jorg; Hosokawa, Keisuke; Ejiri, Mitsumu K.; Nishiyama, Takanori; Takahashi, Toru

    2016-07-01

    The Na layer is normally distributed from 80 to 110 km, and the height range is corresponding to the ionospheric D and E region. In the polar region, the energetic particles precipitating from the magnetosphere can often penetrate into the E region and even into the D region. Thus, the influence of the energetic particles to the Na layer is one of interests in the aspect of the atmospheric composition change accompanied with the auroral activity. There are several previous studies in this issue. For example, recently, we have reported an initial result on a clear relationship between the electron density increase (due to the energetic particles) and the Na density decrease from observational data sets obtained by Na lidar, EISCAT VHF radar, and optical instruments at Tromsoe, Norway on 24-25 January 2012. However, all of the previous studies had been carried out based on case studies by ground-based lidar observations. In this study, we have performed, for the first time, statistical analysis using Na density data from 2004 to 2009 obtained with the Optical Spectrograph and InfraRed Imager System (OSIRIS) onboard Odin satellite. In the presentation, we will show relationship between the Na density and geomagnetic activities, and its latitudinal variation. Based on these results, the Na layer response to the energetic particles will be discussed.

  6. Preparation of Al-La Master Alloy by Thermite Reaction in NaF-NaCl-KCl Molten Salt

    NASA Astrophysics Data System (ADS)

    Jang, Poknam; Li, Hyonmo; Kim, Wenjae; Wang, Zhaowen; Liu, Fengguo

    2015-05-01

    A NaF-NaCl-KCl ternary system containing La2O3 was investigated for the preparation of Al-La master alloy by the thermite reaction method. The solubility of La2O3 in NaF-NaCl-KCl molten salt was determined by the method of isothermal solution saturation. Inductively coupled plasma-optical emission spectroscopy and x-ray diffraction (XRD) analyses were used to consider the content of La2O3 in molten salt and the supernatant composition of molten salt after dissolution of La2O3, respectively. The results showed that the content of NaF had a positive influence on the solubility of La2O3 in NaF-NaCl-KCl molten salts, and the solubility of La2O3 could reach 8.71 wt.% in molten salts of 50 wt.%NaF-50 wt.% (44 wt.%NaCl + 56 wt.%KCl). The XRD pattern of cooling molten salt indicated the formation of LaOF in molten salt, which was probably obtained by the reaction between NaF and La2O3. The kinetic study showed that the thermite reaction was in accord with a first-order reaction model. The main influence factors on La content in the Al-La master alloy product, including molten salt composition, amount of Al, concentration of La2O3, stirring, reduction time and temperature, were investigated by single-factor experimentation. The content of La in the Al-La master alloy could be reached to 10.1 wt.%.

  7. Unidirectional Flux Balance of Monovalent Ions in Cells with Na/Na and Li/Na Exchange: Experimental and Computational Studies on Lymphoid U937 Cells

    PubMed Central

    Vereninov, Igor A.; Yurinskaya, Valentina E.; Model, Michael A.; Vereninov, Alexey A.

    2016-01-01

    Monovalent ion traffic across the cell membrane occurs via various pathways. Evaluation of individual fluxes in whole cell is hampered by their strong interdependence. This difficulty can be overcome by computational analysis of the whole cell flux balance. However, the previous computational studies disregarded ion movement of the self-exchange type. We have taken this exchange into account. The developed software allows determination of unidirectional fluxes of all monovalent ions via the major pathways both under the balanced state and during transient processes. We show how the problem of finding the rate coefficients can be solved by measurement of monovalent ion concentrations and some of the fluxes. Interdependence of fluxes due to the mandatory conditions of electroneutrality and osmotic balance and due to specific effects can be discriminated, enabling one to identify specific changes in ion transfer machinery under varied conditions. To test the effectiveness of the developed approach we made use of the fact that Li/Na exchange is known to be an analogue of the coupled Na/Na exchange. Thus, we compared the predicted and experimental data obtained on U937 cells under varied Li+ concentrations and following inhibition of the sodium pump with ouabain. We found that the coupled Na/Na exchange in U937 cells comprises a significant portion of the entire Na+ turnover. The data showed that the loading of the sodium pump by Li/Na exchange involved in the secondary active Li+ transport at 1–10 mM external Li+ is small. This result may be extrapolated to similar Li+ and Na+ flux relationships in erythrocytes and other cells in patients treated with Li+ in therapeutic doses. The developed computational approach is applicable for studying various cells and can be useful in education for demonstrating the effects of individual transporters and channels on ion gradients, cell water content and membrane potential. PMID:27159324

  8. Jahn–Teller Assisted Na Diffusion for High Performance Na Ion Batteries

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Li, Xin; Wang, Yan; Wu, Di

    2016-08-30

    Na energy storage technology is strategically attractive for large scale applications such as grid energy storage. Here, we show in this paper that there is a clear relation between the Jahn$-$Teller activity of a transition metal ion at the end of charge and the mobility of Na in a cathode material. This is particularly important as mobility at the end of charge limits the capacity of current materials. Consequently, by using this classical piece of physics in the battery world, it is possible to create higher capacity Na-cathode materials. Even more exciting is that the ideal element to impart thismore » effect on cathodes is Fe, which is the least expensive of the transition metal oxides and can therefore enable low cost cathode materials.« less

  9. Testing the influenza–tuberculosis selective mortality hypothesis with Union Army data⋆

    PubMed Central

    Noymer, Andrew

    2009-01-01

    Using Cox regression, this paper shows a weak association between having tuberculosis and dying from influenza among Union Army veterans in late nineteenth-century America. It has been suggested elsewhere [Noymer, A. and M. Garenne (2000). The 1918 influenza epidemic’s effects on sex differentials in mortality in the United States. Population and Development Review 26(3), 565–581.] that the 1918 influenza pandemic accelerated the decline of tuberculosis, by killing many people with tuberculosis. The question remains whether individuals with tuberculosis were at greater risk of influenza death, or if the 1918/post-1918 phenomenon arose from the sheer number of deaths in the influenza pandemic. The present findings, from microdata, cautiously point toward an explanation of Noymer and Garenne’s selection effect in terms of age-overlap of the 1918 pandemic mortality and tuberculosis morbidity, a phenomenon I term “passive selection”. Another way to think of this is selection at the cohort, as opposed to individual, level. PMID:19304361

  10. Controlled phase stability of highly Na-active triclinic structure in nanoscale high-voltage Na2-2xCo1+xP2O7 cathode for Na-ion batteries

    NASA Astrophysics Data System (ADS)

    Song, Hee Jo; Kim, Jae-Chan; Dar, Mushtaq Ahmad; Kim, Dong-Wan

    2018-02-01

    With the increasing demand for high energy density in energy-storage systems, a high-voltage cathode is essential in rechargeable Li-ion and Na-ion batteries. The operating voltage of a triclinic-polymorph Na2CoP2O7, also known as the rose form, is above 4.0 V (vs. Na/Na+), which is relatively high compared to that of other cathode materials. Thus, it can be employed as a potential high-voltage cathode material in Na-ion batteries. However, it is difficult to synthesize a pure rose phase because of its low phase stability, thus limiting its use in high-voltage applications. Herein, compositional-engineered, rose-phase Na2-2xCo1+xP2O7/C (x = 0, 0.1 and 0.2) nanopowder are prepared using a wet-chemical method. The Na2-2xCo1+xP2O7/C cathode shows high electrochemical reactivity with Na ions at 4.0 V, delivering high capacity and high energy density.

  11. Electrogenic Na+/Ca2+ Exchange

    PubMed Central

    Danaceau, Jonathan P.; Lucero, Mary T.

    2000-01-01

    Olfactory receptor neurons (ORNs) from the squid, Lolliguncula brevis, respond to the odors l-glutamate or dopamine with increases in internal Ca2+ concentrations ([Ca2+]i). To directly asses the effects of increasing [Ca2+]i in perforated-patched squid ORNs, we applied 10 mM caffeine to release Ca2+ from internal stores. We observed an inward current response to caffeine. Monovalent cation replacement of Na+ from the external bath solution completely and selectively inhibited the caffeine-induced response, and ruled out the possibility of a Ca2+-dependent nonselective cation current. The strict dependence on internal Ca2+ and external Na+ indicated that the inward current was due to an electrogenic Na+/Ca2+ exchanger. Block of the caffeine-induced current by an inhibitor of Na+/Ca2+ exchange (50–100 μM 2′,4′-dichlorobenzamil) and reversibility of the exchanger current, further confirmed its presence. We tested whether Na+/Ca2+ exchange contributed to odor responses by applying the aquatic odor l-glutamate in the presence and absence of 2′,4′-dichlorobenzamil. We found that electrogenic Na+/Ca2+ exchange was responsible for ∼26% of the total current associated with glutamate-induced odor responses. Although Na+/Ca2+ exchangers are known to be present in ORNs from numerous species, this is the first work to demonstrate amplifying contributions of the exchanger current to odor transduction. PMID:10828249

  12. Optimization of NaOH Molarity, LUSI Mud/Alkaline Activator, and Na2SiO3/NaOH Ratio to Produce Lightweight Aggregate-Based Geopolymer

    PubMed Central

    Abdul Razak, Rafiza; Abdullah, Mohd Mustafa Al Bakri; Hussin, Kamarudin; Ismail, Khairul Nizar; Hardjito, Djwantoro; Yahya, Zarina

    2015-01-01

    This paper presents the mechanical function and characterization of an artificial lightweight geopolymer aggregate (ALGA) using LUSI (Sidoarjo mud) and alkaline activator as source materials. LUSI stands for LU-Lumpur and SI-Sidoarjo, meaning mud from Sidoarjo which erupted near the Banjarpanji-1 exploration well in Sidoarjo, East Java, Indonesia on 27 May 2006. The effect of NaOH molarity, LUSI mud/Alkaline activator (LM/AA) ratio, and Na2SiO3/NaOH ratio to the ALGA are investigated at a sintering temperature of 950 °C. The results show that the optimum NaOH molarity found in this study is 12 M due to the highest strength (lowest AIV value) of 15.79% with lower water absorption and specific gravity. The optimum LUSI mud/Alkaline activator (LM/AA) ratio of 1.7 and the Na2SiO3/NaOH ratio of 0.4 gives the highest strength with AIV value of 15.42% with specific gravity of 1.10 g/cm3 and water absorption of 4.7%. The major synthesized crystalline phases were identified as sodalite, quartz and albite. Scanning Electron Microscope (SEM) image showed more complete geopolymer matrix which contributes to highest strength of ALGA produced. PMID:26006238

  13. Zero-gravity growth of NaF-NaCl eutectics in the NASA Skylab program

    NASA Technical Reports Server (NTRS)

    Yue, A. S.; Allen, F. G.; Yu, J. G.

    1976-01-01

    Continuous and discontinuous NaF fibers, embedded in a NaCl matrix, were produced in space and on earth. The production of continuous fibers in a eutectic mixture is attributed to the absence of convection current in the liquid during solidification in space. Image transmission and optical transmittance measurements of transverse sections of the space-grown and earth-grown ingots were made with a light microscope and a spectrometer. It is shown that better optical properties were obtained from samples grown in space. This was attributed to a better alignment of NaF fibers along the ingot axis. A new concept is advanced to explain the phenomenon of transmittance versus far infrared wavelength of the directionally solidified NaCl-NaF eutectic in terms of the two-dimensional Bragg Scattering and the polarization effect of Rayleigh scattering. This concept can be applied to other eutectic systems as long as the index of refraction of the matrix over a range of wavelengths is known. Experimental data are in agreement with the theoretical prediction.

  14. Light-driven Na + pump from Gillisia limnaea: A high-affinity Na + binding site is formed transiently in the photocycle

    DOE PAGES

    Balashov, Sergei P.; Imasheva, Eleonora S.; Dioumaev, Andrei K.; ...

    2014-11-06

    A group of microbial retinal proteins most closely related to the proton pump xanthorhodopsin has a novel sequence motif and a novel function. Instead of, or in addition to, proton transport, they perform light-driven sodium ion transport, as reported for one representative of this group (KR2) from Krokinobacter. In this paper, we examine a similar protein, GLR from Gillisia limnaea, expressed in Escherichia coli, which shares some properties with KR2 but transports only Na +. The absorption spectrum of GLR is insensitive to Na + at concentrations of ≤3 M. However, very low concentrations of Na + cause profound differencesmore » in the decay and rise time of photocycle intermediates, consistent with a switch from a “Na +-independent” to a “Na +-dependent” photocycle (or photocycle branch) at ~60 μM Na +. The rates of photocycle steps in the latter, but not the former, are linearly dependent on Na + concentration. This suggests that a high-affinity Na + binding site is created transiently after photoexcitation, and entry of Na + from the bulk to this site redirects the course of events in the remainder of the cycle. A greater concentration of Na + is needed for switching the reaction path at lower pH. The data suggest therefore competition between H + and Na + to determine the two alternative pathways. The idea that a Na + binding site can be created at the Schiff base counterion is supported by the finding that upon perturbation of this region in the D251E mutant, Na + binds without photoexcitation. Furthermore, binding of Na+ to the mutant shifts the chromophore maximum to the red like that of H +, which occurs in the photocycle of the wild type.« less

  15. RNA adducts with Na 2SeO 4 and Na 2SeO 3 - Stability and structural features

    NASA Astrophysics Data System (ADS)

    Nafisi, Shohreh; Manouchehri, Firouzeh; Montazeri, Maryam

    2011-12-01

    Selenium compounds are widely available in dietary supplements and have been extensively studied for their antioxidant and anticancer properties. Low blood Se levels were found to be associated with an increased incidence and mortality from various types of cancers. Although many in vivo and clinical trials have been conducted using these compounds, their biochemical and chemical mechanisms of efficacy are the focus of much current research. This study was designed to examine the interaction of Na 2SeO 4 and Na 2SeO 3 with RNA in aqueous solution at physiological conditions, using a constant RNA concentration (6.25 mM) and various sodium selenate and sodium selenite/polynucleotide (phosphate) ratios of 1/80, 1/40, 1/20, 1/10, 1/5, 1/2 and 1/1. Fourier transform infrared, UV-Visible spectroscopic methods were used to determine the drug binding modes, the binding constants, and the stability of Na 2SeO 4 and Na 2SeO 3-RNA complexes in aqueous solution. Spectroscopic evidence showed that Na 2SeO 4 and Na 2SeO 3 bind to the major and minor grooves of RNA ( via G, A and U bases) with some degree of the Se-phosphate (PO 2) interaction for both compounds with overall binding constants of K(Na 2SeO 4-RNA) = 8.34 × 10 3 and K(Na 2SeO 3-RNA) = 4.57 × 10 3 M -1. The order of selenium salts-biopolymer stability was Na 2SeO 4-RNA > Na 2SeO 3-RNA. RNA aggregations occurred at higher selenium concentrations. No biopolymer conformational changes were observed upon Na 2SeO 4 and Na 2SeO 3 interactions, while RNA remains in the A-family structure.

  16. Na Diffusion in Quasi One-Dimensional Ion Conductor NaMn2O4 Observed by μ+SR

    NASA Astrophysics Data System (ADS)

    Umegaki, Izumi; Nozaki, Hiroshi; Harada, Masashi; Månsson, Martin; Sakurai, Hiroya; Kawasaki, Ikuto; Watanabe, Isao; Sugiyama, Jun

    A quasi one-dimensional (1D) compound, NaMn2O4, in which Mn2O4 zigzag chains form a 1D channel along the b-axis and Na ions locate at the center of the channel, is thought to be a good Na ionic conductor. In order to study Na-ion diffusion, we have measured μ+SR spectra using a powder sample in the temperature range between 100 and 500 K. A diffusive behavior was clearly observed above 325 K. Assuming a thermal activate process for jump diffusion of Na-ion between two nearest neighboring sites, a self diffusion coefficient of Na ion (DNa) and its activation energy (Ea) were estimated as DNa = (3.1 ± 0.2) × 10 - 11 cm2/s at 350 K and Ea = 180(9) meV.

  17. High-Performance Na-O2 Batteries Enabled by Oriented NaO2 Nanowires as Discharge Products.

    PubMed

    Khajehbashi, S Mohammad B; Xu, Lin; Zhang, Guobin; Tan, Shuangshuang; Zhao, Yan; Wang, Lai-Sen; Li, Jiantao; Luo, Wen; Peng, Dong-Liang; Mai, Liqiang

    2018-06-13

    Na-O 2 batteries are emerging rechargeable batteries due to their high theoretical energy density and abundant resources, but they suffer from sluggish kinetics due to the formation of large-size discharge products with cubic or irregular particle shapes. Here, we report the unique growth of discharge products of NaO 2 nanowires inside Na-O 2 batteries that significantly boosts the performance of Na-O 2 batteries. For this purpose, a high-spin Co 3 O 4 electrocatalyst was synthesized via the high-temperature oxidation of pure cobalt nanoparticles in an external magnetic field. The discharge products of NaO 2 nanowires are 10-20 nm in diameter and ∼10 μm in length, characteristics that provide facile pathways for electron and ion transfer. With these nanowires, Na-O 2 batteries have surpassed 400 cycles with a fixed capacity of 1000 mA h g -1 , an ultra-low over-potential of ∼60 mV during charging, and near-zero over-potential during discharging. This strategy not only provides a unique way to control the morphology of discharge products to achieve high-performance Na-O 2 batteries but also opens up the opportunity to explore growing nanowires in novel conditions.

  18. 24Mg(p, α) 21Na reaction study for spectroscopy of 21Na

    DOE PAGES

    Cha, S. M.; Chae, K. Y.; Kim, A.; ...

    2015-11-03

    The Mg-24(p, alpha)Na-21 reaction was measured at the Holifield Radioactive Ion Beam Facility at Oak Ridge National Laboratory in order to better constrain the spins and parities of the energy levels in Na-21 for the astrophysically important F-17(alpha, p)Ne-20 reaction rate calculation. 31-MeV proton beams from the 25-MV tandem accelerator and enriched Mg-24 solid targets were used. When recoiling He-4 particles from the Mg-24(p, alpha)Na-21 reaction we used a highly segmented silicon detector array to detect them; it measured the yields of He-4 particles over a range of angles simultaneously. A observed a new level at 6661 ± 5 keVmore » in the present work. The extracted angular distributions for the first four levels of Na-21 and the results from distorted wave Born approximation (DWBA) calculations were compared to verify and extract the angular momentum transfer.« less

  19. Insight to the Thermal Decomposition and Hydrogen Desorption Behaviors of NaNH2-NaBH4 Hydrogen Storage Composite.

    PubMed

    Pei, Ziwei; Bai, Ying; Wang, Yue; Wu, Feng; Wu, Chuan

    2017-09-20

    The lightweight compound material NaNH 2 -NaBH 4 is regarded as a promising hydrogen storage composite due to the high hydrogen density. Mechanical ball milling was employed to synthesize the composite NaNH 2 -NaBH 4 (2/1 molar ratio), and the samples were investigated utilizing thermogravimetric-differential thermal analysis-mass spectroscopy (TG-DTA-MS), X-ray diffraction (XRD), and Fourier transform infrared spectroscopy (FTIR) analyses. The full-spectrum test (range of the ratio of mass to charge: 0-200) shows that the released gaseous species contain H 2 , NH 3 , B 2 H 6 , and N 2 in the heating process from room temperature to 400 °C, and possibly the impurity gas B 6 H 12 also exists. The TG/DTA analyses show that the composite NaNH 2 -NaBH 4 (2/1 molar ratio) is conductive to generate hydrogen so that the dehydrogenation process can be finished before 400 °C. Moreover, the thermal decomposition process from 200 to 400 °C involves two-step dehydrogenation reactions: (1) Na 3 (NH 2 ) 2 BH 4 hydride decomposes into Na 3 BN 2 and H 2 (200-350 °C); (2) remaining Na 3 (NH 2 ) 2 BH 4 reacts with NaBH 4 and Na 3 BN 2 , generating Na, BN, NH 3 , N 2 , and H 2 (350-400 °C). The better mechanism understanding of the thermal decomposition pathway lays a foundation for tailoring the hydrogen storage performance of the composite complex hydrides system.

  20. Sodium channel diversity in the vestibular ganglion: NaV1.5, NaV1.8, and tetrodotoxin-sensitive currents

    PubMed Central

    2016-01-01

    Firing patterns differ between subpopulations of vestibular primary afferent neurons. The role of sodium (NaV) channels in this diversity has not been investigated because NaV currents in rodent vestibular ganglion neurons (VGNs) were reported to be homogeneous, with the voltage dependence and tetrodotoxin (TTX) sensitivity of most neuronal NaV channels. RT-PCR experiments, however, indicated expression of diverse NaV channel subunits in the vestibular ganglion, motivating a closer look. Whole cell recordings from acutely dissociated postnatal VGNs confirmed that nearly all neurons expressed NaV currents that are TTX-sensitive and have activation midpoints between −30 and −40 mV. In addition, however, many VGNs expressed one of two other NaV currents. Some VGNs had a small current with properties consistent with NaV1.5 channels: low TTX sensitivity, sensitivity to divalent cation block, and a relatively negative voltage range, and some VGNs showed NaV1.5-like immunoreactivity. Other VGNs had a current with the properties of NaV1.8 channels: high TTX resistance, slow time course, and a relatively depolarized voltage range. In two NaV1.8 reporter lines, subsets of VGNs were labeled. VGNs with NaV1.8-like TTX-resistant current also differed from other VGNs in the voltage dependence of their TTX-sensitive currents and in the voltage threshold for spiking and action potential shape. Regulated expression of NaV channels in primary afferent neurons is likely to selectively affect firing properties that contribute to the encoding of vestibular stimuli. PMID:26936982

  1. Enhancement of the sulfur capture capacity of limestones by the addition of Na2CO3 and NaCl.

    PubMed

    Laursen, K; Grace, J R; Lim, C J

    2001-11-01

    The ability of Na2CO3 and NaCl to enhance the sulfur capture capacity of three limestones was evaluated via fixed-bed calcination and sulfation experiments. The tested limestones represent three different sulfation morphologies: unreacted-core, network, and uniformly sulfated. Treatment with aqueous or powdered Na2CO3 significantly increased the Ca-utilization for two stones which normally sulfate in an unreacted-core pattern (20% to 45%) and network pattern (33% to 49%). The increase was lower for the uniformly sulfated stone (44% to 48%). Na2CO3 treatment increased the number of macropores leading to uniform sulfation of all particles, nearly eliminating the normal strong dependence of utilization on limestone type and particle size. The effect of Na2CO3 is believed to be associated with formation of a eutectic melt which enhances ionic diffusion and accelerates molecular rearrangement of the CaO. Treatment with aqueous NaCl solution caused a decrease in utilization, probably due to formation of large grains and plugging of pores caused by formation of a large amount of eutectic melt. The effect of Na2CO3 is less sensitive than that of NaCl to the amount added and the combustion environment (temperature and gas composition). In addition, Na2CO3 neither promotes corrosion nor forms chlorinated byproducts, which are main concerns associated with NaCl. Thus, Na2CO3 appears to have significant advantages over NaCl for enhancement of limestone sulfur capture capacity in fluidized-bed combustors.

  2. Concentration dependence of Li+/Na+ diffusion in manganese hexacyanoferrates

    NASA Astrophysics Data System (ADS)

    Takachi, Masamitsu; Fukuzumi, Yuya; Moritomo, Yutaka

    2016-06-01

    Manganese hexacyanoferrates (Mn-HCFs) with a jungle-gym-type structure are promising cathode materials for Li+/Na+ secondary batteries (LIBs/SIBs). Here, we investigated the diffusion constants D Li/D Na of Li+/Na+ against the Li+/Na+ concentration x Na/x Li and temperature (T) of A 1.32Mn[Fe(CN)6]0.833.6H2O (A = Li and Na). We evaluated the activation energy E\\text{a}\\text{Li}/E\\text{a}\\text{Na} of D Li/D Na against x Na/x Li. We found that E\\text{a}\\text{Na} steeply increases with x Na from 0.41 eV at x Na = 0.69 to 0.7 eV at 1.1. The increase in E\\text{a}\\text{Na} is ascribed to the occupancy effect of the Na+ site. The increase in E\\text{a}\\text{Li} is suppressed, probably because the number of Li+ sites is three times that of Na+ sites.

  3. Carbon dioxide sequestration using NaHSO4 and NaOH: A dissolution and carbonation optimisation study.

    PubMed

    Sanna, Aimaro; Steel, Luc; Maroto-Valer, M Mercedes

    2017-03-15

    The use of NaHSO 4 to leach out Mg fromlizardite-rich serpentinite (in form of MgSO 4 ) and the carbonation of CO 2 (captured in form of Na 2 CO 3 using NaOH) to form MgCO 3 and Na 2 SO 4 was investigated. Unlike ammonium sulphate, sodium sulphate can be separated via precipitation during the recycling step avoiding energy intensive evaporation process required in NH 4 -based processes. To determine the effectiveness of the NaHSO 4 /NaOH process when applied to lizardite, the optimisation of the dissolution and carbonation steps were performed using a UK lizardite-rich serpentine. Temperature, solid/liquid ratio, particle size, concentration and molar ratio were evaluated. An optimal dissolution efficiency of 69.6% was achieved over 3 h at 100 °C using 1.4 M sodium bisulphate and 50 g/l serpentine with particle size 75-150 μm. An optimal carbonation efficiency of 95.4% was achieved over 30 min at 90 °C and 1:1 magnesium:sodium carbonate molar ratio using non-synthesised solution. The CO 2 sequestration capacity was 223.6 g carbon dioxide/kg serpentine (66.4% in terms of Mg bonded to hydromagnesite), which is comparable with those obtained using ammonium based processes. Therefore, lizardite-rich serpentinites represent a valuable resource for the NaHSO 4 /NaOH based pH swing mineralisation process. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Personnel Attrition Rates in Historical Land Combat Operations: An Annotated Bibliography

    DTIC Science & Technology

    1993-06-01

    1986, Combat Casualties Among US Navy Personnel in Vietnam. Cochrane-1959, The 3rd Division at Chateau Thierry , July 1918. Cockrell-1974, Research Study...Chateau Thierry , July 1918. CIVIL Fox-1889, Regimental Losses in the American Civil War, 1861-1865. Livermore-1900, Numbers and Losses in the Civil War... Thierry , July 1918. Wainstein-1973b, Rates of Advance in Infantry Division Attacks in the Normandy-Northern France and Siegfried Line Campaigns. DURATION

  5. Domestic Security Cooperation: A Unified Approach to Homeland Security and Defense

    DTIC Science & Technology

    2012-09-01

    counter the threats to homeland security that included the Espionage Act of 1917 and the Sedition Act of 1918. National Defense Act of 1916...the threats to homeland security that included the Espionage Act of 1917 and the Sedition Act of 1918. The Espionage Act of 1917 outlawed interfering...years or both.”12 The Sedition Act of 1918 broadened this law by including the U.S. government and prohibited uttering, printing, writing, or

  6. Northeast Minneapolis: Location and Movement in an Ethnic Community.

    DTIC Science & Technology

    1979-06-01

    not resurrected again until 1918 when all three suffered political reversals at nearly the same moment. Between 1795 and 1918 a person from the region...birth Germany, Russia, Austria, or simply Poland. Since Poland did not exist as a nation from the Third Partition of 1795 to 1918 , it is remarkable...little significance in absolute and percentage terms in 1905 Minneapolis (Figures 3-38 and 3-39). Romania , France, Luxembourg, Switzerland, Denmark

  7. Characterization and antibacterial activity of silver exchanged regenerated NaY zeolite from surfactant-modified NaY zeolite.

    PubMed

    Salim, Mashitah Mad; Malek, Nik Ahmad Nizam Nik

    2016-02-01

    The antibacterial activity of regenerated NaY zeolite (thermal treatment from cetyltrimethyl ammonium bromide (CTAB)-modified NaY zeolite and pretreatment with Na ions) loaded with silver ions were examined using the broth dilution minimum inhibitory concentration (MIC) method against Escherichia coli (E. coli ATCC 11229) and Staphylococcus aureus (S. aureus ATCC 6538). X-ray diffraction (XRD), attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and chemical elemental analyses were used to characterize the regenerated NaY and AgY zeolites. The XRD patterns indicated that the calcination and addition of silver ions on regenerated NaY zeolite did not affect the structure of the regenerated NaY zeolite as the characteristic peaks of the NaY zeolite were retained, and no new peaks were observed. The regenerated AgY zeolite showed good antibacterial activity against both bacteria strains in distilled water, and the antibacterial activity of the samples increased with increasing Ag loaded on the regenerated AgY zeolite; the regenerated AgY zeolite was more effective against E. coli than S. aureus. However, the antibacterial activity of the regenerated AgY was not effective in saline solution for both bacteria. The study showed that CTAB-modified NaY zeolite materials could be regenerated to NaY zeolite using thermal treatment (550°C, 5h) and this material has excellent performance as an antibacterial agent after silver ions loading. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Adsorption and Formation of Small Na Clusters on Pristine and Double-Vacancy Graphene for Anodes of Na-Ion Batteries.

    PubMed

    Liang, Zhicong; Fan, Xiaofeng; Zheng, Weitao; Singh, David J

    2017-05-24

    Layered carbon is a likely anode material for Na-ion batteries (NIBs). Graphitic carbon has a low capacity of approximately 35 (mA h)/g due to the formation of NaC 64 . Using first-principles methods including van der Waals interactions, we analyze the adsorption of Na ions and clusters on graphene in the context of anodes. The interaction between Na ions and graphene is found to be weak. Small Na clusters are not stable on the surface of pristine graphene in the electrochemical environment of NIBs. However, we find that Na ions and clusters can be stored effectively on defected graphene that has double vacancies. In addition, the adsorption energy of small Na clusters near a double vacancy is found to decrease with increasing cluster size. With high concentrations of vacancies the capacity of Na on defective graphene is found to be as much as 10-30 times higher than that of graphitic carbon.

  9. Shoot Na+ Exclusion and Increased Salinity Tolerance Engineered by Cell Type–Specific Alteration of Na+ Transport in Arabidopsis[W][OA

    PubMed Central

    Møller, Inge S.; Gilliham, Matthew; Jha, Deepa; Mayo, Gwenda M.; Roy, Stuart J.; Coates, Juliet C.; Haseloff, Jim; Tester, Mark

    2009-01-01

    Soil salinity affects large areas of cultivated land, causing significant reductions in crop yield globally. The Na+ toxicity of many crop plants is correlated with overaccumulation of Na+ in the shoot. We have previously suggested that the engineering of Na+ exclusion from the shoot could be achieved through an alteration of plasma membrane Na+ transport processes in the root, if these alterations were cell type specific. Here, it is shown that expression of the Na+ transporter HKT1;1 in the mature root stele of Arabidopsis thaliana decreases Na+ accumulation in the shoot by 37 to 64%. The expression of HKT1;1 specifically in the mature root stele is achieved using an enhancer trap expression system for specific and strong overexpression. The effect in the shoot is caused by the increased influx, mediated by HKT1;1, of Na+ into stelar root cells, which is demonstrated in planta and leads to a reduction of root-to-shoot transfer of Na+. Plants with reduced shoot Na+ also have increased salinity tolerance. By contrast, plants constitutively expressing HKT1;1 driven by the cauliflower mosaic virus 35S promoter accumulated high shoot Na+ and grew poorly. Our results demonstrate that the modification of a specific Na+ transport process in specific cell types can reduce shoot Na+ accumulation, an important component of salinity tolerance of many higher plants. PMID:19584143

  10. NMR studies on Na+ transport in Synechococcus PCC 6311

    NASA Technical Reports Server (NTRS)

    Nitschmann, W. H.; Packer, L.

    1992-01-01

    The freshwater cyanobacterium Synechococcus PCC 6311 is able to adapt to grow after sudden exposure to salt (NaCl) stress. We have investigated the mechanism of Na+ transport in these cells during adaptation to high salinity. Na+ influx under dark aerobic conditions occurred independently of delta pH or delta psi across the cytoplasmic membrane, ATPase activity, and respiratory electron transport. These findings are consistent with the existence of Na+/monovalent anion cotransport or simultaneous Na+/H+ +anion/OH- exchange. Na+ influx was dependent on Cl-, Br-, NO3-, or NO2-. No Na+ uptake occurred after addition of NaI, NaHCO3, or Na2SO4. Na+ extrusion was absolutely dependent on delta pH and on an ATPase activity and/or on respiratory electron transport. This indicates that Na+ extrusion via Na+/H+ exchange is driven by primary H+ pumps in the cytoplasmic membrane. Cells grown for 4 days in 0.5 m NaCl medium, "salt-grown cells," differ from control cells by a lower maximum velocity of Na+ influx and by lower steady-state ratios of [Na+]in/[Na+]out. These results indicate that cells grown in high-salt medium increase their capacity to extrude Na+. During salt adaptation Na+ extrusion driven by respiratory electron transport increased from about 15 to 50%.

  11. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... replication competent forms of the 1918 pandemic influenza virus containing any portion of the coding regions of all eight gene segments (Reconstructed 1918 Influenza virus) Ricin Rickettsia prowazekii SARS...

  12. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... virus Monkeypox virus Reconstructed replication competent forms of the 1918 pandemic influenza virus containing any portion of the coding regions of all eight gene segments (Reconstructed 1918 Influenza virus...

  13. 42 CFR 73.3 - HHS select agents and toxins.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... replication competent forms of the 1918 pandemic influenza virus containing any portion of the coding regions of all eight gene segments (Reconstructed 1918 Influenza virus) Ricin Rickettsia prowazekii SARS...

  14. Interaction of NaOH solutions with silica surfaces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rimsza, Jessica M.; Jones, Reese E.; Criscenti, Louise J.

    Sodium adsorption on silica surfaces depends on the solution counter-ion. Here, we use NaOH solutions to investigate basic environments. Sodium adsorption on hydroxylated silica surfaces from NaOH solutions were investigated through molecular dynamics with a dissociative force field, allowing for the development of secondary molecular species. Furthermore, across the NaOH concentrations (0.01 M – 1.0 M), ~50% of the Na + ions were concentrated in the surface region, developing silica surface charges between –0.01 C/m 2 (0.01 M NaOH) and –0.76 C/m 2 (1.0 M NaOH) due to surface site deprotonation. Five inner-sphere adsorption complexes were identified, including monodentate, bidentate,more » and tridentate configurations and two additional structures, with Na + ions coordinated by bridging oxygen and hydroxyl groups or water molecules. Coordination of Na + ions by bridging oxygen atoms indicates partial or complete incorporation of Na + ions into the silica surface. Residence time analysis identified that Na + ions coordinated by bridging oxygen atoms stayed adsorbed onto the surface four times longer than the mono/bi/tridentate species, indicating formation of relatively stable and persistent Na + ion adsorption structures. Such inner-sphere complexes form only at NaOH concentrations of > 0.5 M. Na + adsorption and lifetimes have implications for the stability of silica surfaces.« less

  15. Interaction of NaOH solutions with silica surfaces

    DOE PAGES

    Rimsza, Jessica M.; Jones, Reese E.; Criscenti, Louise J.

    2018-01-16

    Sodium adsorption on silica surfaces depends on the solution counter-ion. Here, we use NaOH solutions to investigate basic environments. Sodium adsorption on hydroxylated silica surfaces from NaOH solutions were investigated through molecular dynamics with a dissociative force field, allowing for the development of secondary molecular species. Furthermore, across the NaOH concentrations (0.01 M – 1.0 M), ~50% of the Na + ions were concentrated in the surface region, developing silica surface charges between –0.01 C/m 2 (0.01 M NaOH) and –0.76 C/m 2 (1.0 M NaOH) due to surface site deprotonation. Five inner-sphere adsorption complexes were identified, including monodentate, bidentate,more » and tridentate configurations and two additional structures, with Na + ions coordinated by bridging oxygen and hydroxyl groups or water molecules. Coordination of Na + ions by bridging oxygen atoms indicates partial or complete incorporation of Na + ions into the silica surface. Residence time analysis identified that Na + ions coordinated by bridging oxygen atoms stayed adsorbed onto the surface four times longer than the mono/bi/tridentate species, indicating formation of relatively stable and persistent Na + ion adsorption structures. Such inner-sphere complexes form only at NaOH concentrations of > 0.5 M. Na + adsorption and lifetimes have implications for the stability of silica surfaces.« less

  16. Accessing naïve human pluripotency

    PubMed Central

    De Los Angeles, Alejandro; Loh, Yuin-Han; Tesar, Paul J; Daley, George Q

    2014-01-01

    Pluripotency manifests during mammalian development through formation of the epiblast, founder tissue of the embryo proper. Rodent pluripotent stem cells can be considered as two distinct states: naïve and primed. Naïve pluripotent stem cell lines are distinguished from primed cells by self-renewal in response to LIF signaling and MEK/GSK3 inhibition (LIF/2i conditions) and two active X chromosomes in female cells. In rodent cells, the naïve pluripotent state may be accessed through at least three routes: explantation of the inner cell mass, somatic cell reprogramming by ectopic Oct4, Sox2, Klf4, and C-myc, and direct reversion of primed post-implantation-associated epiblast stem cells (EpiSCs). In contrast to their rodent counterparts, human embryonic stem cells and induced pluripotent stem cells more closely resemble rodent primed EpiSCs. A critical question is whether naïve human pluripotent stem cells with bona fide features of both a pluripotent state and naïve-specific features can be obtained. In this review, we outline current understanding of the differences between these pluripotent states in mice, new perspectives on the origins of naïve pluripotency in rodents, and recent attempts to apply the rodent paradigm to capture naïve pluripotency in human cells. Unraveling how to stably induce naïve pluripotency in human cells will influence the full realization of human pluripotent stem cell biology and medicine. PMID:22463982

  17. Obituary: William F. M. Buscombe, 1918-2003

    NASA Astrophysics Data System (ADS)

    Taam, Ronald Everett; Bahng, John D. R.

    2003-12-01

    William Buscombe, an emeritus professor at Northwestern University, died from a massive stroke on 13 March 2003. He was a stellar spectroscopist and was working on the 16th edition of his catalog, entitled ``MK Spectral Classifications" at the time of his death. Bill was born on 12 February 1918 in Hamilton, Canada to Ethel Minett Buscombe and William Henry Buscombe. His mother was a business woman prior to marriage and his father was an executive secretary to a fire insurance company. His interest in astronomy was stimulated by a mathematics teacher in grade school and this interest carried over to his undergraduate years at the University of Toronto where he worked as a research assistant measuring stellar spectra at the David Dunlop Observatory. He earned a BA degree in Mathematics and Physics in 1940. Upon graduation he entered the graduate program in meteorology under the Department of Transport of the Government of Canada and worked as a meteorologist for the Canadian government until 1945. His studies and service eventually led to a MA degree in Meteorology from the University of Toronto in 1948. From the period 1945 to 1948, Bill was an instructor in the Department of Mathematics at the University of Saskatchewan. During the summer of 1947 Bill resumed his research in astronomy working with Andew McKellar in a study of the intensities of molecular bands in R-type stars at the Dominion Astrophysical Observatory. Subsequently, Bill entered into the graduate program in the Department of Astronomy at Princeton University where he worked with Martin Schwarzschild and Lyman Spitzer, Jr. In 1950, he was awarded a PhD in Astronomy for his thesis entitled, ``Spectrophotometry of Early A-Type Stars." Bill joined the staff at the Mt. Wilson and Palomar Observatories as a Fellow of the Carnegie Institution of Washington from 1950--1952. During this period he spent a significant amount of time observing at Mount Wilson studying the variations of atomic absorption lines

  18. Neutron diffraction studies of the Na-ion battery electrode materials NaCoCr{sub 2}(PO{sub 4}){sub 3}, NaNiCr{sub 2}(PO{sub 4}){sub 3}, and Na{sub 2}Ni{sub 2}Cr(PO{sub 4}){sub 3}

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yahia, H. Ben; Essehli, R., E-mail: ressehli@qf.org.qa; Avdeev, M.

    The new compounds NaCoCr{sub 2}(PO{sub 4}){sub 3}, NaNiCr{sub 2}(PO{sub 4}){sub 3}, and Na{sub 2}Ni{sub 2}Cr(PO{sub 4}){sub 3} were synthesized by sol-gel method and their crystal structures were determined by using neutron powder diffraction data. These compounds were characterized by galvanometric cycling and cyclic voltammetry. NaCoCr{sub 2}(PO{sub 4}){sub 3}, NaNiCr{sub 2}(PO{sub 4}){sub 3}, and Na{sub 2}Ni{sub 2}Cr(PO{sub 4}){sub 3} crystallize with a stuffed α-CrPO{sub 4}-type structure. The structure consists of a 3D-framework made of octahedra and tetrahedra that are sharing corners and/or edges generating channels along [100] and [010], in which the sodium atoms are located. Of significance, in the structuresmore » of NaNiCr{sub 2}(PO{sub 4}){sub 3}, and Na{sub 2}Ni{sub 2}Cr(PO{sub 4}){sub 3} a statistical disorder Ni{sup 2+}/Cr{sup 3+} was observed on both the 8g and 4a atomic positions, whereas in NaCoCr{sub 2}(PO{sub 4}){sub 3} the statistical disorder Co{sup 2+}/Cr{sup 3+} was only observed on the 8g atomic position. When tested as negative electrode materials, NaCoCr{sub 2}(PO{sub 4}){sub 3}, NaNiCr{sub 2}(PO{sub 4}){sub 3}, and Na{sub 2}Ni{sub 2}Cr(PO{sub 4}){sub 3} delivered specific capacities of 352, 385, and 368 mA h g{sup −1}, respectively, which attests to the electrochemical activity of sodium in these compounds. - Highlights: • NaCoCr{sub 2}(PO{sub 4}){sub 3}, NaNiCr{sub 2}(PO{sub 4}){sub 3}, and Na{sub 2}Ni{sub 2}Cr(PO{sub 4}){sub 3} were synthesized by sol-gel method. • The crystal structures were determined by using neutron powder diffraction data. • The three compounds crystallize with a stuffed α-CrPO{sub 4}-type structure. • The three compounds were tested as anodes in sodium-ion batteries. • Relatively high specific capacities were obtained for these compounds.« less

  19. Transcriptional regulators of Na,K-ATPase subunits

    PubMed Central

    Li, Zhiqin; Langhans, Sigrid A.

    2015-01-01

    The Na,K-ATPase classically serves as an ion pump creating an electrochemical gradient across the plasma membrane that is essential for transepithelial transport, nutrient uptake and membrane potential. In addition, Na,K-ATPase also functions as a receptor, a signal transducer and a cell adhesion molecule. With such diverse roles, it is understandable that the Na,K-ATPase subunits, the catalytic α-subunit, the β-subunit and the FXYD proteins, are controlled extensively during development and to accommodate physiological needs. The spatial and temporal expression of Na,K-ATPase is partially regulated at the transcriptional level. Numerous transcription factors, hormones, growth factors, lipids, and extracellular stimuli modulate the transcription of the Na,K-ATPase subunits. Moreover, epigenetic mechanisms also contribute to the regulation of Na,K-ATPase expression. With the ever growing knowledge about diseases associated with the malfunction of Na,K-ATPase, this review aims at summarizing the best-characterized transcription regulators that modulate Na,K-ATPase subunit levels. As abnormal expression of Na,K-ATPase subunits has been observed in many carcinoma, we will also discuss transcription factors that are associated with epithelial-mesenchymal transition, a crucial step in the progression of many tumors to malignant disease. PMID:26579519

  20. Sepsis does not alter red blood cell glucose metabolism or Na+ concentration: A 2H-, 23Na-NMR study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hotchkiss, R.S.; Song, S.K.; Ling, C.S.

    The effects of sepsis on intracellular Na+ concentration ((Na+)i) and glucose metabolism were examined in rat red blood cells (RBCs) by using 23Na- and 2H-nuclear magnetic resonance (NMR) spectroscopy. Sepsis was induced in 15 halothane-anesthetized female Sprague-Dawley rats by using the cecal ligation and perforation technique; 14 control rats underwent cecal manipulation without ligation. The animals were fasted for 36 h, but allowed free access to water. At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent. Human RBCs from 17 critically ill nonseptic patients and from 7 patients who were diagnosedmore » as septic were also examined for (Na+)i. Five rat RBC specimens had (Na+)i determined by both 23Na-NMR and inductively coupled plasma-atomic emission spectroscopy (ICP-AES). For glucose metabolism studies, RBCs from septic and control rats were suspended in modified Krebs-Henseleit buffer containing (6,6-2H2)glucose and examined by 2H-NMR. No significant differences in (Na+)i or glucose utilization were found in RBCs from control or septic rats. There were no differences in (Na+)i in the two groups of patients. The (Na+)i determined by NMR spectroscopy agreed closely with measurements using ICP-AES and establish that 100% of the (Na+)i of the RBC is visible by NMR. Glucose measurements determined by 2H-NMR correlated closely (correlation coefficient = 0.93) with enzymatic analysis. These studies showed no evidence that sepsis disturbed RBC membrane function or metabolism.« less

  1. [Effect of NaHCO3 stress on uptake and transportation of Na+, K+ and Ca2+ in three shrub species].

    PubMed

    Mao, Gui-Lian; Li, Guo-Qi; Xu, Xing; Zhang, Xin-Xue

    2014-03-01

    We detected absorption and transportation of ions in the leaves of Atriplex nummularia, Atriplex canescens and Lycium barbarum under NaHCO3 stress (300 mmol x L(-1)) by using atomic absorption spectrophotometry and non-invasive ion flux measurement. The results showed that leaves of the A. nummularia, A. canescens and L. barbarum exhibited a high capacity to induce the Na+ accumulation when compared with that of control. The higher the concentration of NaHCO3 treatment, the more Na+ accumulated in the leaves of the three plants under experimental condition. L. barbarum showed a higher Na+ efflux in the mesophyll cells, whereas A. nummularia and A. canescens showed a relative lower efflux. A lower K+ content and a higher Na+/K+ ratio were detected in leaves of A. nummularia and L. barbarum. However, a higher K+ content and a lower Na+/K+ ratio were seen in leaves of A. canescens. Due to induction of Ca2+ efflux under the NaHCO3 treatment, a lower Ca2+ content and a higher Na+/Ca2+ ratio were observed in L. barbarum. On the contrary, a higher Ca2+ influx was observed in A. nummularia and A. canescens. These results suggested that the three shrubs species had different Na+ segmentation strategies. The accumulation of Na+ inhibited Ca2+ absorption in leaves of L. barbarum, while in the A. nummularia and A. canescens, Ca2+ influx induced [Ca2+]cyt which preserved a less-depolarized PM and then inhibited K efflux. The maintaining of cellular K+/Na+ homeostasis in A. nummularia and A. canescens might be achieved by the induction of [Ca2+]cyt under the NaHCO3 treatment.

  2. High pressure structural stability of the Na-Te system

    NASA Astrophysics Data System (ADS)

    Wang, Youchun; Tian, Fubo; Li, Da; Duan, Defang; Xie, Hui; Liu, Bingbing; Zhou, Qiang; Cui, Tian

    2018-03-01

    The ab initio evolutionary algorithm is used to search for all thermodynamically stable Na-Te compounds at extreme pressure. In our calculations, several new structures are discovered at high pressure, namely, Imma Na2Te, Pmmm NaTe, Imma Na8Te2 and P4/mmm NaTe3. Like the known structures of Na2Te (Fm-3m, Pnma and P63/mmc), the Pmmm NaTe, Imma Na8Te2 and P4/mmm NaTe3 structures also show semiconductor properties with band-gap decreases when pressure increased. However, we find that the band-gap of Imma Na2Te structure increases with pressure. We presume that the result may be caused by the increasing of splitting between Te p states and Na s, Na p and Te d states. Furthermore, we think that the strong hybridization between Na p state and Te d state result in the band gap increasing with pressure.

  3. FTIR spectra of the solid solutions (Na0.88K0.12)VO3, (Na0.5K0.5)VO3, and Na(V0.66P0.34)O3

    NASA Astrophysics Data System (ADS)

    de Waal, D.; Heyns, A. M.

    1992-03-01

    It is known that three different solid solutions, (Na0.88K0.12)VO3, (Na0.5K0.5)VO3 and Na(V0.66P0.34)O3, form in the (Na,K)(V,P)O3 system. These compounds all have monoclinic crystal structures similar to the pure alkali metal metavanadates containing small cations, e.g. Li+ and Na+ (Space group C2/c). Metavanadates with large cations like K+, Rb+, C+s and NH+4 form orthorhombic crystals, space group Pbcm. All those are structurally related to the silicate pyroxenes. Na(V0.66P0.34)O3 and (Na0.88K0.12)VO3 have the same modified diopside structure as (alpha) - NaVO3 while (Na0.5K0.5)VO3 adopts the true diopside structure. The infrared spectra of the three solid solutions are reported here in comparison with those of (alpha) -NaVO3 and KVO3. The results are also correlated with those obtained in two independent high pressure Raman studies of NH4VO3 and RbVO3 as the introduction of a larger cation like K+ should increase the pressure in the structure.

  4. The U.S. Air Service in World War I. Volume III. The Battle of St. Mihiel

    DTIC Science & Technology

    1979-01-01

    the greatest possible extent. PRACTICE EXERCISES. The more practice excercises of aerial liaison with infantry that can be carried out, the better. It...Operations Office Operations Report, 17:00, Sept. 11th, 1918. Sept. 12th, 1918. 1. Atmospheric Conditions. Very cloudy and raining intermittently ...American E.F. September 12th, 1918 Operations Report No 12 From: 19 h 00 Sept 11th to 17 h 00 Sept 12th. 1. Atmospheric conditions: Intermittent rain and

  5. A computational study of Na behavior on graphene

    NASA Astrophysics Data System (ADS)

    Malyi, Oleksandr I.; Sopiha, Kostiantyn; Kulish, Vadym V.; Tan, Teck L.; Manzhos, Sergei; Persson, Clas

    2015-04-01

    We present the first ab initio and molecular dynamics study of Na adsorption and diffusion on ideal graphene that considers Na-Na interaction and dispersion forces. From density functional theory (DFT) calculations using the generalized gradient approximation (GGA), the binding energy (vs. the vacuum reference state) of -0.75 eV is higher than the cohesive energy of Na metal (ENa metal cohesive energy (EcohDFT - D = - 1.21 eV) when dispersion correction is included (DFT-D), with Eb = -1.14 eV. Both DFT and DFT-D predict that the increase of Na concentration on graphene results in formation of Na complexes. This is evidenced by smaller Bader charge on Na atoms of Na dimer, 0.55e (0.48e for DFT) compared to 0.86e (for both DFT and DFT-D) for the single atom adsorption as well as by the formation of a Nasbnd Na bond identified by analysis of the electron density. These results suggest that ideal graphene is not a promising anode material for Na-ion batteries. Analysis of diffusion pathways for a Na dimer shows that the dimer remains stable during the diffusion, and computed migration barriers are significantly lower for the dimer than that for the single atom diffusion. This indicates that Na-Na interaction should be taken into account during the analysis of Na transport on graphene. Finally, we show that the typical defects (vacancy and divacancy) induce significant strengthening of the Nasbnd C interaction. In particular, the largest change to the interaction is computed for vacancy-defected graphene, where the found lowest binding energy (vs. the metal reference state) is about 1.15 eV (1.21 eV for DFT) lower than that for ideal graphene.

  6. Thyroid thermogenesis. Relationships between Na+-dependent respiration and Na+ + K+-adenosine triphosphatase activity in rat skeletal muscle.

    PubMed Central

    Asano, Y; Liberman, U A; Edelman, I S

    1976-01-01

    The effect of thyroid status on QO2, QO2 (t) and NaK-ATPase activity was examined in rat skeletal muscle. QO2(t) (i.e. Na+-transport-dependent respiration) was estimated with ouabain or Na+-free media supplemented with K+. In contrast to the effects of ouabain on ion composition, intracellular K+ was maintained at about 125 meq/liter, and intracellular Na+ was almost nil in the Na+-free media. The estimates of QO2(t) were independent of the considerable differences in tissue ion concentrations. The increase in QO2(t) account for 47% of the increase in QO2 in the transition from the hypothyroid to the euthyroid state and 84% of the increase in the transition from the euthyroid to the hyperthyroid state. Surgical thyroidectomy lowered NaK-ATPase activity of the microsomal fraction (expressed per milligram protein) 32%; injections of triodothyronine (T3) increased this activity 75% in initially hypothyroid rats and 26% in initially euthyroid rats. Thyroidectomy was attended by significant falls in serum Ca and Pi concentrations. Administration of T3 resulted in further declines in serum Ca and marked increases in serum Ps concentrations. Similar effects were seen in 131I-treated rats, but the magnitude of the declines in serum Ca were less. The effects of T3 on QO2, QO2(t), and NaK-ATPase activity of skeletal muscle were indistinguishable in the 131I-ablated and surgically thyroidectomized rats. In thyroidectomized or euthyroid rats given repeated doses of T3, QO2(t) and NaA-ATPase activity increased proportionately. In thyroidectomized rats injected with single doses of T3, either 10, 50, or 250 mug/100 g body wt, QO2(t) increased linearly with NaK-ATPase activity. The kinetics of the NaK-ATPase activity was assessed with an ATP-generating system. T3 elicited a significant increase in Vmax with no change in Km for ATP. PMID:130385

  7. Laser-induced chemiluminescence of NaMg

    NASA Astrophysics Data System (ADS)

    Benard, D. J.; Michels, H. H.

    1982-03-01

    An unstructured continuum emission around 670 nm was observed when Mg was added to an optically pumped heat pipe containing Na and K vapor, in good agreement with ab initio calculations of the NaMg potential energy curves. The corresponding excitation spectrum showed that the incident radiation was observed by NaK molecules (X → C transitions).

  8. KSC-2014-1933

    NASA Image and Video Library

    2014-04-02

    CAPE CANAVERAL, Fla. – Tony Corak, manager of nondestructive testing services for PaR Systems Inc., speaks during an Open House event at Hangar N at Cape Canaveral Air Force Station in Florida, to celebrate the one-year anniversary of a partnership with NASA Kennedy Space Center. Under a 15-year lease agreement, PaR Systems is utilizing Hangar N and its unique nondestructive testing equipment. The partnership agreement was established by Kennedy's Center Planning and Development Directorate. The agreement is just one example of the types of partnerships that Kennedy is seeking to create a multi-user spaceport. Photo credit: NASA/Cory Huston

  9. Advancement of technology towards developing Na-ion batteries

    NASA Astrophysics Data System (ADS)

    Jamesh, Mohammed Ibrahim; Prakash, A. S.

    2018-02-01

    The Na-ion-batteries are considered much attention for the next-generation power-sources due to the high abundance of Na resources that lower the cost and become the alternative for the state of the art Li-ion batteries in future. In this review, the recently reported potential cathode and anode candidates for Na-ion-batteries are identified in-light-of-their high-performance for the development of Na-ion-full-cells. Further, the recent-progress on the Na-ion full-cells including the strategies used to improve the high cycling-performance (stable even up-to 50000 cycles), operating voltage (even ≥ 3.7 V), capacity (>350 mAhg-1 even at 1000 mAg-1 (based-on-mass-of-the-anode)), and energy density (even up-to 400 Whkg-1) are reviewed. In addition, Na-ion-batteries with the electrodes containing reduced graphene oxide, and the recent developments on symmetric Na-ion-batteries are discussed. Further, this paper identifies the promising Na-ion-batteries including the strategies used to assemble full-cell using hard-carbon-anodes, Na3V2(PO4)3 cathodes, and other-electrode-materials. Then, comparison between aqueous and non-aqueous Na-ion-batteries in terms of voltage and energy density has been given. Later, various types of electrolytes used for Na-ion-batteries including aqueous, non-aqueous, ionic-liquids and solid-state electrolytes are discussed. Finally, commercial and technological-developments on Na-ion-batteries are provided. The scientific and engineering knowledge gained on Na-ion-batteries afford conceivable development for practical application in near future.

  10. Negative electrodes for Na-ion batteries.

    PubMed

    Dahbi, Mouad; Yabuuchi, Naoaki; Kubota, Kei; Tokiwa, Kazuyasu; Komaba, Shinichi

    2014-08-07

    Research interest in Na-ion batteries has increased rapidly because of the environmental friendliness of sodium compared to lithium. Throughout this Perspective paper, we report and review recent scientific advances in the field of negative electrode materials used for Na-ion batteries. This paper sheds light on negative electrode materials for Na-ion batteries: carbonaceous materials, oxides/phosphates (as sodium insertion materials), sodium alloy/compounds and so on. These electrode materials have different reaction mechanisms for electrochemical sodiation/desodiation processes. Moreover, not only sodiation-active materials but also binders, current collectors, electrolytes and electrode/electrolyte interphase and its stabilization are essential for long cycle life Na-ion batteries. This paper also addresses the prospect of Na-ion batteries as low-cost and long-life batteries with relatively high-energy density as their potential competitive edge over the commercialized Li-ion batteries.

  11. Obituary: Kenneth Ingvard Greisen, 1918-2007

    NASA Astrophysics Data System (ADS)

    Greisen, Eric W.

    2007-12-01

    Cornell University Emeritus Professor of Physics, Kenneth I. Greisen, died on March 17, 2007 of cancer at the Hospicare residence in Ithaca, New York. He was 89 years old. Prof. Greisen was well-known for his participation in the Manhattan Project at Los Alamos and for his many contributions to the study of cosmic ray physics. More quietly, Prof. Greisen also made significant contributions to the teaching of Physics at the high school and university levels. He was of service to the Cornell and Ithaca communities in many ways both during his university career and after his retirement. Kenneth Ingvard Greisen was born in Perth Amboy, New Jersey, on January 24, 1918, to Signa and Ingvard Greisen. Ken attended Wagner College 1934-1935 and then Franklin and Marshall College, where he ran on the track team and graduated summa cum laude with the prestigious Henry S. Williamson Medalist award in 1938. Ken then entered graduate school in physics at Cornell University, where he became the first American student of the eminent Italian physicist Bruno B. Rossi. Together they carried out a study that yielded quantitative verification of the relativistic dilation of time intervals and an improved estimate of the mean life of mesotrons at rest. Their review article on ``Cosmic Ray Theory'' in 1941 was a standard for many years. Ken's Ph.D. thesis entitled ``Intensity of Cosmic Rays at Low Altitude and the Origin of the Soft Component,'' along with related articles, appeared in 1942 and 1943. During this very productive period, Ken also married Betty Chase, a Cornell biology graduate student. Upon graduation, Ken joined the Manhattan Project in Los Alamos, New Mexico. He was among the leaders of the group that designed and built the explosive charge that initiated the nuclear reaction in the first atomic bomb. Witnessing the July 16, 1945 Trinity explosion, he provided an eyewitness account that has become an important historical record. After the explosion, in a remark typical of

  12. Bucrates lanista Rehn 1918 (Tettigoniidae: Conocephalinae): The First Record from the Brazilian Pantanal, the First Description of the Male, the First Karyotypic Report for the Genus, and the First Telomeric Hybridization of the Subfamily.

    PubMed

    Chamorro-Rengifo, Juliana; Olivier, Renan da Silva; Araujo, Douglas

    2016-10-01

    Bucrates lanista, the most southerly distributed species in the genus Bucrates Burmeister, was originally described from Brazil based on a female collected in the state of Rio Grande do Sul, but the species has not been recorded since 1918. In this work, we report that B. lanista inhabits the Pantanal Wetland in the state of Mato Grosso do Sul and, for the first time, describe the male. Individuals of B. lanista are gregarious and present a brown/green color dimorphism; this behavior and color variation are also observed in species of closely related genera. Individuals from the Pantanal vary slightly from those of Rio Grande do Sul. The karyotype was determined to be 2n♂ = 21 = 20 + X0 and 2n♀ = 22 = 20 + XX. The X chromosome is metacentric and the largest of the complement, and all of the autosomes are submetacentrics. All chromosomes solely present telomeric (TTAGG)n repeats at their ends, and some chromosomes present positive and negative DAPI bands.

  13. The Na(+) transporter, TaHKT1;5-D, limits shoot Na(+) accumulation in bread wheat.

    PubMed

    Byrt, Caitlin Siobhan; Xu, Bo; Krishnan, Mahima; Lightfoot, Damien James; Athman, Asmini; Jacobs, Andrew Keith; Watson-Haigh, Nathan S; Plett, Darren; Munns, Rana; Tester, Mark; Gilliham, Matthew

    2014-11-01

    Bread wheat (Triticum aestivum L.) has a major salt tolerance locus, Kna1, responsible for the maintenance of a high cytosolic K(+) /Na(+) ratio in the leaves of salt stressed plants. The Kna1 locus encompasses a large DNA fragment, the distal 14% of chromosome 4DL. Limited recombination has been observed at this locus making it difficult to map genetically and identify the causal gene. Here, we decipher the function of TaHKT1;5-D, a candidate gene underlying the Kna1 locus. Transport studies using the heterologous expression systems Saccharomyces cerevisiae and Xenopus laevis oocytes indicated that TaHKT1;5-D is a Na(+) -selective transporter. Transient expression in Arabidopsis thaliana mesophyll protoplasts and in situ polymerase chain reaction indicated that TaHKT1;5-D is localised on the plasma membrane in the wheat root stele. RNA interference-induced silencing decreased the expression of TaHKT1;5-D in transgenic bread wheat lines which led to an increase in the Na(+) concentration in the leaves. This indicates that TaHKT1;5-D retrieves Na(+) from the xylem vessels in the root and has an important role in restricting the transport of Na(+) from the root to the leaves in bread wheat. Thus, TaHKT1;5-D confers the essential salinity tolerance mechanism in bread wheat associated with the Kna1 locus via shoot Na(+) exclusion and is critical in maintaining a high K(+) /Na(+) ratio in the leaves. These findings show there is potential to increase the salinity tolerance of bread wheat by manipulation of HKT1;5 genes. © 2014 The Authors The Plant Journal © 2014 John Wiley & Sons Ltd.

  14. Elastic Coulomb breakup of 34Na

    NASA Astrophysics Data System (ADS)

    Singh, G.; Shubhchintak, Chatterjee, R.

    2016-08-01

    Background: 34Na is conjectured to play an important role in the production of seed nuclei in the alternate r -process paths involving light neutron rich nuclei very near the β -stability line, and as such, it is important to know its ground state properties and structure to calculate rates of the reactions it might be involved in, in the stellar plasma. Found in the region of `island of inversion', its ground state might not be in agreement with normal shell model predictions. Purpose: The aim of this paper is to study the elastic Coulomb breakup of 34Na on 208Pb to give us a core of 33Na with a neutron and in the process we try and investigate the one neutron separation energy and the ground state configuration of 34Na. Method: A fully quantum mechanical Coulomb breakup theory within the architecture of post-form finite range distorted wave Born approximation extended to include the effects of deformation is used to research the elastic Coulomb breakup of 34Na on 208Pb at 100 MeV/u. The triple differential cross section calculated for the breakup is integrated over the desired components to find the total cross-section, momentum, and angular distributions as well as the average momenta, along with the energy-angular distributions. Results: The total one neutron removal cross section is calculated to test the possible ground state configurations of 34Na. The average momentum results along with energy-angular calculations indicate 34Na to have a halo structure. The parallel momentum distributions with narrow full widths at half-maxima signify the same. Conclusion: We have attempted to analyze the possible ground state configurations of 34Na and in congruity with the patterns in the `island of inversion' conclude that even without deformation, 34Na should be a neutron halo with a predominant contribution to its ground state most probably coming from 33Na(3 /2+)⊗ 2 p3 /2ν configuration. We also surmise that it would certainly be useful and rewarding to test our

  15. JPRS Report, East Europe

    DTIC Science & Technology

    1987-12-16

    Romania’s claim to Transylvania. Romania carried out its threats and signed a provisional peace treaty with Germany on 7 March 1918 . The cable sent by...Oct 87] 3 Economist Weighs Structural Reforms in Soviet-Type Economies [L1STY No 5, Oct 87] 4 HUNGARY U.S. Plan for Central Europe in 1918 ...in 1918 Examined 25000003 Budapest HISTORIA in Hungarian No 4, 1987 pp 16-20 [Article by Magda Adam, former Wilson Center fellow: "An Amercian

  16. Resurgent current of voltage-gated Na+ channels

    PubMed Central

    Lewis, Amanda H; Raman, Indira M

    2014-01-01

    Resurgent Na+ current results from a distinctive form of Na+ channel gating, originally identified in cerebellar Purkinje neurons. In these neurons, the tetrodotoxin-sensitive voltage-gated Na+ channels responsible for action potential firing have specialized mechanisms that reduce the likelihood that they accumulate in fast inactivated states, thereby shortening refractory periods and permitting rapid, repetitive, and/or burst firing. Under voltage clamp, step depolarizations evoke transient Na+ currents that rapidly activate and quickly decay, and step repolarizations elicit slower channel reopening, or a ‘resurgent’ current. The generation of resurgent current depends on a factor in the Na+ channel complex, probably a subunit such as NaVβ4 (Scn4b), which blocks open Na+ channels at positive voltages, competing with the fast inactivation gate, and unblocks at negative voltages, permitting recovery from an open channel block along with a flow of current. Following its initial discovery, resurgent Na+ current has been found in nearly 20 types of neurons. Emerging research suggests that resurgent current is preferentially increased in a variety of clinical conditions associated with altered cellular excitability. Here we review the biophysical, molecular and structural mechanisms of resurgent current and their relation to the normal functions of excitable cells as well as pathophysiology. PMID:25172941

  17. Painful Na-channelopathies: an expanding universe.

    PubMed

    Waxman, Stephen G

    2013-07-01

    The universe of painful Na-channelopathies--human disorders caused by mutations in voltage-gated sodium channels--has recently expanded in three dimensions. We now know that mutations of sodium channels cause not only rare genetic 'model disorders' such as inherited erythromelalgia and channelopathy-associated insensitivity to pain but also common painful neuropathies. We have learned that mutations of NaV1.8, as well as mutations of NaV1.7, can cause painful Na-channelopathies. Moreover, recent studies combining atomic level structural models and pharmacogenomics suggest that the goal of genomically guided pain therapy may not be unrealistic. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Integrated Control of Na Transport along the Nephron

    PubMed Central

    Schnermann, Jürgen

    2015-01-01

    The kidney filters vast quantities of Na at the glomerulus but excretes a very small fraction of this Na in the final urine. Although almost every nephron segment participates in the reabsorption of Na in the normal kidney, the proximal segments (from the glomerulus to the macula densa) and the distal segments (past the macula densa) play different roles. The proximal tubule and the thick ascending limb of the loop of Henle interact with the filtration apparatus to deliver Na to the distal nephron at a rather constant rate. This involves regulation of both filtration and reabsorption through the processes of glomerulotubular balance and tubuloglomerular feedback. The more distal segments, including the distal convoluted tubule (DCT), connecting tubule, and collecting duct, regulate Na reabsorption to match the excretion with dietary intake. The relative amounts of Na reabsorbed in the DCT, which mainly reabsorbs NaCl, and by more downstream segments that exchange Na for K are variable, allowing the simultaneous regulation of both Na and K excretion. PMID:25098598

  19. Electrical resistivity of liquid Na-alkali alloys

    NASA Astrophysics Data System (ADS)

    Malan, Rajesh C.; Vora, Aditya M.

    2018-05-01

    The electrical resistivity (ρ) has been investigated for the liquid Na-alkali alloys. An effort is made to extend the applicability of the potential suggested by Fiolhais and co-workers to the liquid range for alkali group. The universal parameters of the potential are used for the entire calculation. Eight different screening functions proposed by Hartree (H), Hubbard and Sham (HS), Vashishtha and Shingwi (VS), Taylor (T), Ichimaru and Utsumi (IU), Farid et al. (F), Sarkar et al. (S) and Nagy (N) are used to study the electrical resistivity (ρ) of liquid Na-alkali alloys with well-known Faber-Ziman theory along with Percus-Yevic hard sphere (PYHS) reference system. The results of electrical resistivity (ρ) are found in qualitative agreement with experimental data for the Na-K and Na-Rb alloys than those for Na-Li and Na-Cs alloys.

  20. The Na+ transport in gram-positive bacteria defect in the Mrp antiporter complex measured with 23Na nuclear magnetic resonance.

    PubMed

    Górecki, Kamil; Hägerhäll, Cecilia; Drakenberg, Torbjörn

    2014-01-15

    (23)Na nuclear magnetic resonance (NMR) has previously been used to monitor Na(+) translocation across membranes in gram-negative bacteria and in various other organelles and liposomes using a membrane-impermeable shift reagent to resolve the signals resulting from internal and external Na(+). In this work, the (23)Na NMR method was adapted for measurements of internal Na(+) concentration in the gram-positive bacterium Bacillus subtilis, with the aim of assessing the Na(+) translocation activity of the Mrp (multiple resistance and pH) antiporter complex, a member of the cation proton antiporter-3 (CPA-3) family. The sodium-sensitive growth phenotype observed in a B. subtilis strain with the gene encoding MrpA deleted could indeed be correlated to the inability of this strain to maintain a lower internal Na(+) concentration than an external one. Copyright © 2013 Elsevier Inc. All rights reserved.