Sample records for nacp mid-continent intensive

  1. The Vulcan Project: Recent advances and emissions estimation for the NACP mid-continent intensive campaign region

    NASA Astrophysics Data System (ADS)

    Gurney, K. R.; Zhou, Y.; Geethakumar, S.; Godbole, A.; Mendoza, D. L.; Vaidhyanathan, M.; Sahni, N.

    2009-12-01

    The Vulcan Project has quantified 2002 fossil fuel CO2 for the US at the sub-county/hourly scale and is a key component of attributing CO2 fluxes within the North American Carbon Program. Vulcan approached quantification of CO2 emissions by leveraging information already contained within regulatory and monitoring agencies including the US EPA’s Acid Rain Program, the EPA’s National Emissions Inventory for the assessment of nationally regulated air pollution, the Department of Energy, the U.S. Census and the Department of Transportation. By utilizing the inventory emissions of carbon monoxide combined with fuel/device-specific emission factors, we have calculated CO2 emissions for industrial point sources, power plants, mobile sources, residential and commercial sectors with information on fuel used and source classification information. In this presentation, I provide critical recent advances in the Vulcan Project with particular emphasis on our contribution to the NACP mid-continent intensive campaign. Version 1.2 of the Vulcan fossil fuel CO2 emissions inventory includes the 2008 US Census road atlas, overcoming many of the missing roads and links that were prevalent in previous road atlas releases. This offers better spatial allocation of the onroad emissions. Figure 1 shows the improved road layer density for the MCI study region. Furthermore the temporal dimension of onroad emissions have been improved through the use of hourly traffic monitoring data at roughly 6000 monitoring locations across the US. The residential and commercial sector emissions now have hourly time structure via a spatially explicit heating degree day calculation utilizing the North American Regional Reanalysis temperature output. Finally, we have generated a multiyear (1997-2008) data product for the MCI region through use of Energy Information Administration state-level fuel sales data. Figure 1. improved road density via utilization of the new 2008 US census road layer. Left

  2. The Second "Ring of Towers": Over-sampling the Mid Continent Intensive region CO2 mixing ratio?

    NASA Astrophysics Data System (ADS)

    Richardson, S.; Miles, N.; Davis, K.; Crosson, E.; Denning, S.; Zupanksi, D.; Uliasz, M.

    2007-12-01

    A central barrier preventing the scientific community from understanding the carbon balance of the continent is methodological; it is technically difficult to bridge the gap in spatial scales that exists between the detailed understanding of ecological processes that can be gathered via intensive local field study, and the overarching but mechanistically poor understanding of the global carbon cycle that is gained by analyzing the atmospheric CO2 budget. The NACP's Midcontinental Intensive (MCI) study seeks to bridge this gap by conducting a rigorous methodological test of our ability to measure the terrestrial carbon balance of the upper Midwest. A critical need in bridging this gap is increased data density. A primary goal of the project is to increase the regional atmospheric CO2 data density so that 1) atmospheric inversions can derive well-constrained regional ecosystem carbon flux estimates and 2) the trade off between data density and accuracy of the flux estimates can be determined quantitatively using field observations, thus providing guidance to future observational network designs. Our work adds a regional network of five communications-tower based atmospheric CO2 observations to the planned long-term atmospheric CO2 observing network (tall towers, flux towers and aircraft profiles) in the midcontinent intensive region. Measurements began in April-June 2007, If the measurements are shown to be spatially dense enough to over sample the CO2 mixing ratio, the experiment will provide an upper bounds on the density of measurements required to produce the most accurate flux possible with current atmospheric inversions. The five sites for "Ring 2" and deployment dates are Centerville, IA (Apr 07), Round Lake, MN (May 07), Kewanee, IL (Apr 07), Mead, NE (Apr 07), Galesville, WI (June 07). Two heights are sampled at each tower (30 m AGL and between 110 and 140 m AGL). More details are available at www.ring2.psu.edu. In addition, two systems in PSU's network of

  3. Integrated Mid-Continent Carbon Capture, Sequestration & Enhanced Oil Recovery Project

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brian McPherson

    2010-08-31

    A consortium of research partners led by the Southwest Regional Partnership on Carbon Sequestration and industry partners, including CAP CO2 LLC, Blue Source LLC, Coffeyville Resources, Nitrogen Fertilizers LLC, Ash Grove Cement Company, Kansas Ethanol LLC, Headwaters Clean Carbon Services, Black & Veatch, and Schlumberger Carbon Services, conducted a feasibility study of a large-scale CCS commercialization project that included large-scale CO{sub 2} sources. The overall objective of this project, entitled the 'Integrated Mid-Continent Carbon Capture, Sequestration and Enhanced Oil Recovery Project' was to design an integrated system of US mid-continent industrial CO{sub 2} sources with CO{sub 2} capture, and geologicmore » sequestration in deep saline formations and in oil field reservoirs with concomitant EOR. Findings of this project suggest that deep saline sequestration in the mid-continent region is not feasible without major financial incentives, such as tax credits or otherwise, that do not exist at this time. However, results of the analysis suggest that enhanced oil recovery with carbon sequestration is indeed feasible and practical for specific types of geologic settings in the Midwestern U.S.« less

  4. Multimetric Macroinvertebrate Indices for Mid-continent US Great Rivers

    EPA Science Inventory

    We developed a set of great river macroinvertebrate indices of condition (GRMICs) for the mid-continent great rivers. We used a multiscale (site, reach, landscape) multimetric abiotic stressor gradient to select macroinvertebrate assemblage metrics sensitive to human disturbance ...

  5. Improving Access to MODIS Biophysical Science Products for NACP Investigators

    NASA Technical Reports Server (NTRS)

    Wolfe, Robert E.; Gao, Feng; Morisette, Jeffrey T.; Ederer, Gregory A.; Pedelty, Jeffrey A.

    2007-01-01

    MODIS 4 NACP is a NASA-funded project supporting the North American Carbon Program (NACP). The purpose of this Advancing Collaborative Connections for Earth-Sun System Science (ACCESS) project is to provide researchers with Moderate Resolution Imaging Spectroradiometer (MODIS) biophysical data products that are custom tailored for use in NACP model studies. Standard MODIS biophysical products provide used to improve our understanding on the climate and ecosystem changes. However, direct uses of the MODIS biophysical parameters are constrained by retrieval quality and cloud contamination. Another challenge that NACP users face is acquiring MODIS data in formats and at spatial-temporal resolutions consistent with other data sets they use. We have been working closely with key NACP users to tailor the MODIS products to fit their needs. First, we provide new temporally smoothed and spatially continuous MODIS biophysical data sets. Second, we are distributing MODIS data at suitable spatial-temporal resolutions and in formats consistent with other data integration into model studies.

  6. 77 FR 35959 - Atlas Pipeline Mid-Continent WestTex, LLC; Pioneer Natural Resources USA, Inc.; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-06-15

    ... Mid-Continent WestTex, LLC; Pioneer Natural Resources USA, Inc.; Notice of Application Take notice that on May 30, 2012, Atlas Pipeline Mid-Continent WestTex, LLC (Atlas) and Pioneer Natural Resources..., Senior Counsel, Pioneer Natural Resources USA, Inc., 5205 North O'Connor Blvd., Suite 200, Irving, TX...

  7. Littoral and Shoreline Wood in Mid-continent Great Rivers (USA)

    EPA Science Inventory

    Less is known about the ecology of wood in great rivers than in smaller lotic systems. We used a probability survey to estimate the abundance of littoral and shoreline wood along the mid-continent great rivers of the United States: the Missouri, Upper Mississippi, and the Ohio Ri...

  8. Trucking and Size and Weight Regulations in the Mid-Continent Corridor

    DOT National Transportation Integrated Search

    1996-11-01

    This thesis is an empirical analysis of trucking and truck size and weight (TS&W) regulations in the Mid-continent corridor. Based on this analysis, it compares and contrasts plausible near term TS&W policy options relating to this corridor. The appr...

  9. Costs and Benefits of a Mid-Continent Expansion of Loran-C

    DOT National Transportation Integrated Search

    1979-03-01

    Loran-C chains currently in operation or approved for construction will soon cover not only the U.S. coastal and Great Lakes waters, but also 63 percent of the land area and 92 percent of the population of the contiguous 48 states. The mid-continent ...

  10. The NACP/synuclein gene: chromosomal assignment and screening for alterations in Alzheimer disease.

    PubMed

    Campion, D; Martin, C; Heilig, R; Charbonnier, F; Moreau, V; Flaman, J M; Petit, J L; Hannequin, D; Brice, A; Frebourg, T

    1995-03-20

    The major component of the vascular and plaque amyloid deposits in Alzheimer disease is the amyloid beta peptide (A beta). A second intrinsic component of amyloid, the NAC (non-A beta component of amyloid) peptide, has recently been identified, and its precursor protein was named NACP. A computer homology search allowed us to establish that the human NACP gene was homologous to the rat synuclein gene. We mapped the NACP/synuclein gene to chromosome 4 and cloned three alternatively spliced transcripts in lymphocytes derived from a normal subject. We analyzed by RT-PCR and direct sequencing the entire coding region of the NACP/synuclein gene in a group of patients with familial early onset Alzheimer disease. No mutation was found in 26 unrelated patients. Further studies are required to investigate the implication of the NACP/synuclein gene in Alzheimer disease.

  11. The NACP/synuclein gene: Chromosomal assignment and screening for alterations in Alzheimer disease

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campion, D.; Martin, C.; Charbonnier, F.

    1995-03-20

    The major component of the vascular and plaque amyloid deposits in Alzheimer disease is the amyloid {beta} peptide (A{beta}). A second intrinsic component of amyloid, the NAC (non-A{beta} component of amyloid) peptide, has recently been identified, and its precursor protein was named NACP. A computer homology search allowed us to establish that the human NACP gene was homologous to the rat synuclein gene. We mapped the NACP/synuclein gene to chromosome 4 and cloned three alternatively spliced transcripts in lymphocytes derived from a normal subject. We analyzed by RT-PCR and direct sequencing the entire coding region of the NACP/synuclein gene inmore » a group of patients with familial early onset Alzheimer disease. No mutation was found in 26 unrelated patients. Further studies are required to investigate the implication of the NACP/synuclein gene in Alzheimer disease. 21 refs., 3 tabs.« less

  12. High-rate injection is associated with the increase in U.S. mid-continent seismicity

    USGS Publications Warehouse

    Weingarten, Matthew; Ge, Shemin; Godt, Jonathan W.; Bekins, Barbara A.; Rubinstein, Justin L.

    2015-01-01

    An unprecedented increase in earthquakes in the U.S. mid-continent began in 2009. Many of these earthquakes have been documented as induced by wastewater injection. We examine the relationship between wastewater injection and U.S. mid-continent seismicity using a newly assembled injection well database for the central and eastern United States. We find that the entire increase in earthquake rate is associated with fluid injection wells. High-rate injection wells (>300,000 barrels per month) are much more likely to be associated with earthquakes than lower-rate wells. At the scale of our study, a well’s cumulative injected volume, monthly wellhead pressure, depth, and proximity to crystalline basement do not strongly correlate with earthquake association. Managing injection rates may be a useful tool to minimize the likelihood of induced earthquakes.

  13. Family Planning Services Available to Migratory Farm Workers in the Mid-Continent Streams.

    ERIC Educational Resources Information Center

    Planned Parenthood--World Population, Austin, TX. Southwest Region.

    The information in this directory is designed to promote continuity in family planning services for migrant families in mid-continent streams. It provides professional personnel with a new tool to help meet the distinctive needs of individual migrants. Names, addresses, schedules, methods, and fee information of service agencies (health…

  14. About the Mid-Continent Ecology Division (MED) of EPA's National Health and Environmental Effects Research Laboratory

    EPA Pesticide Factsheets

    The Mid-Continent Ecology Division (MED) conducts innovative research and predictive modeling to document and forecast the effects of pollutants on the integrity of watersheds and freshwater ecosystems.

  15. Wetland dynamics influence mid-continent duck recruitment

    USGS Publications Warehouse

    Anteau, Michael J.; Pearse, Aaron T.; Szymankski, Michael L.

    2013-01-01

    Recruitment is a key factor influencing duck population dynamics. Understanding what regulates recruitment of ducks is a prerequisite to informed habitat and harvest management. Quantity of May ponds (MP) has been linked to recruitment and population size (Kaminski and Gluesing 1987, Raveling and Heitmeyer 1989). However, wetland productivity (quality) is driven by inter-annual hydrological fluctuations. Periodic drying of wetlands due to wet-dry climate cycles releases nutrients and increases invertebrate populations when wet conditions return (Euliss et al. 1999). Wetlands may also become wet or dry within a breeding season. Accordingly, inter-annual and intra-seasonal hydrologic variation potentially influence duck recruitment. Here, we examined influences of wetland quantity, quality, and intra-seasonal dynamics on recruitment of ducks. We indexed duck recruitment by vulnerability-corrected age ratios (juveniles/adult females) for mid-continent Gadwall (Anas strepera). We chose Gadwall because the majority of the continental population breeds in the Prairie Pothole Region (PPR), where annual estimates of MP exist since 1974. We indexed wetland quality by calculating change in MP (?MP) over the past two years (?MP = 0.6[MPt – MPt-1] + 0.4[MPt – MPt-2]). We indexed intra-seasonal change in number of ponds by dividing the PPR mean standardized precipitation index for July by MP (hereafter summer index). MP and ?MP were positively correlated (r = 0.65); therefore, we calculated residual ?MP (?MPr) with a simple linear regression using MP, creating orthogonal variables. Finally, we conducted a multiple regression to examine how MP, ?MPr, and summer index explained variation in recruitment of Gadwall from 1976–2010. Our model explained 67% of the variation in mid-continent Gadwall recruitment and all three hydrologic indices were positively correlated with recruitment (Figure 1). Type II semi-partial R2 estimates indicated that MP accounted for 41%, ?MPr

  16. Modeled summer background concentration nutrients and suspended sediment in the mid-continent (USA) great rivers

    EPA Science Inventory

    We used regression models to predict background concentration of four water quality indictors: total nitrogen (N), total phosphorus (P), chloride, and total suspended solids (TSS), in the mid-continent (USA) great rivers, the Upper Mississippi, the Lower Missouri, and the Ohio. F...

  17. An Assessment of Stressor Extent and Biological Condition in the North American Mid-continent Great Rivers (USA)

    EPA Science Inventory

    We assessed the North American mid-continent great rivers (Upper Mississippi, Missouri, and Ohio). We estimated the extent of each river in most- (MDC) or least-disturbed condition (LDC) based on multiple biological response indicators: fi sh and macroinvertebrate, trophic stat...

  18. One billion year-old Mid-continent Rift leaves virtually no clues in the mantle

    NASA Astrophysics Data System (ADS)

    Bollmann, T. A.; Frederiksen, A. W.; van der Lee, S.; Wolin, E.; Revenaugh, J.; Wiens, D.; Darbyshire, F. A.; Aleqabi, G. I.; Wysession, M. E.; Stein, S.; Jurdy, D. M.

    2017-12-01

    We measured the relative arrival times of more than forty-six thousand teleseismic P waves recorded by seismic stations of Earthscope's Superior Province Rifting Earthscope Experiment (SPREE) and combined them with a similar amount of such measurements from other seismic stations in the larger region. SPREE recorded seismic waves for two and a half years around the prominent, one billion year-old Mid-continent Rift structure. The curvilinear Mid-continent Rift (MR) is distinguished by voluminous one billion year-old lava flows, which produce a prominent gravity high along the MR. As for other seismic waves, these lava flows along with their underplated counterpart, slightly slow down the measured teleseismic P waves, on average, compared to P waves that did not traverse structures beneath the Mid-continent Rift. However, the variance in the P wave arrival times in these two groups is nearly ten times higher than their average difference. In a seismic-tomographic inversion, we mapped all measured arrival times into structures deep beneath the crust, in the Earth's mantle. Beneath the crust we generally find relatively high P velocities, indicating relatively cool and undeformable mantle structures. However, the uppermost mantle beneath the MR shows several patches of slightly decreased P velocities. These patches are coincident with where the gravity anomalies peak, in Iowa and along the northern Minnesota/Wisconsin border. We will report on the likelihood that these anomalies are indeed a remaining mantle-lithospheric signature of the MR or whether these patches indirectly reflect the presence of the lava flows and their underplated counterparts at the crust-mantle interface. Other structures of interest and of varying depth extent in our tomographic image locate at 1) the intersection of the Superior Craton with the Penokean Province and the Marshfield Terrane west of the MR in southern Minnesota, 2) the intersection of the Penokean, Yavapai, and Mazatzal Terranes

  19. Evaluating land cover influences on model uncertainties—A case study of cropland carbon dynamics in the Mid-Continent Intensive Campaign region

    USGS Publications Warehouse

    Li, Zhengpeng; Liu, Shuguang; Zhang, Xuesong; West, Tristram O.; Ogle, Stephen M.; Zhou, Naijun

    2016-01-01

    Quantifying spatial and temporal patterns of carbon sources and sinks and their uncertainties across agriculture-dominated areas remains challenging for understanding regional carbon cycles. Characteristics of local land cover inputs could impact the regional carbon estimates but the effect has not been fully evaluated in the past. Within the North American Carbon Program Mid-Continent Intensive (MCI) Campaign, three models were developed to estimate carbon fluxes on croplands: an inventory-based model, the Environmental Policy Integrated Climate (EPIC) model, and the General Ensemble biogeochemical Modeling System (GEMS) model. They all provided estimates of three major carbon fluxes on cropland: net primary production (NPP), net ecosystem production (NEP), and soil organic carbon (SOC) change. Using data mining and spatial statistics, we studied the spatial distribution of the carbon fluxes uncertainties and the relationships between the uncertainties and the land cover characteristics. Results indicated that uncertainties for all three carbon fluxes were not randomly distributed, but instead formed multiple clusters within the MCI region. We investigated the impacts of three land cover characteristics on the fluxes uncertainties: cropland percentage, cropland richness and cropland diversity. The results indicated that cropland percentage significantly influenced the uncertainties of NPP and NEP, but not on the uncertainties of SOC change. Greater uncertainties of NPP and NEP were found in counties with small cropland percentage than the counties with large cropland percentage. Cropland species richness and diversity also showed negative correlations with the model uncertainties. Our study demonstrated that the land cover characteristics contributed to the uncertainties of regional carbon fluxes estimates. The approaches we used in this study can be applied to other ecosystem models to identify the areas with high uncertainties and where models can be improved to

  20. Reduction of Risk in Exploration and Prospect Generation through a Multidisciplinary Basin-Analysis Program in the South-Central Mid-Continent Region

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Banerjee, S.; Barker, C.; Fite, J.

    1999-04-02

    This report will discuss a series of regional studies that were undertaken within the South-Central Mid-Continent region of the U.S. Coverage is also provided about a series of innovative techniques that were used for this assessment.

  1. Orthotopic bladder substitution in men revisited: identification of continence predictors.

    PubMed

    Koraitim, M M; Atta, M A; Foda, M K

    2006-11-01

    We determined the impact of the functional characteristics of the neobladder and urethral sphincter on continence results, and determined the most significant predictors of continence. A total of 88 male patients 29 to 70 years old underwent orthotopic bladder substitution with tubularized ileocecal segment (40) and detubularized sigmoid (25) or ileum (23). Uroflowmetry, cystometry and urethral pressure profilometry were performed at 13 to 36 months (mean 19) postoperatively. The correlation between urinary continence and 28 urodynamic variables was assessed. Parameters that correlated significantly with continence were entered into a multivariate analysis using a logistic regression model to determine the most significant predictors of continence. Maximum urethral closure pressure was the only parameter that showed a statistically significant correlation with diurnal continence. Nocturnal continence had not only a statistically significant positive correlation with maximum urethral closure pressure, but also statistically significant negative correlations with maximum contraction amplitude, and baseline pressure at mid and maximum capacity. Three of these 4 parameters, including maximum urethral closure pressure, maximum contraction amplitude and baseline pressure at mid capacity, proved to be significant predictors of continence on multivariate analysis. While daytime continence is determined by maximum urethral closure pressure, during the night it is the net result of 2 forces that have about equal influence but in opposite directions, that is maximum urethral closure pressure vs maximum contraction amplitude plus baseline pressure at mid capacity. Two equations were derived from the logistic regression model to predict the probability of continence after orthotopic bladder substitution, including Z1 (diurnal) = 0.605 + 0.0085 maximum urethral closure pressure and Z2 (nocturnal) = 0.841 + 0.01 [maximum urethral closure pressure - (maximum contraction amplitude

  2. Repeat prostate biopsies prior to radical prostatectomy do not impact erectile function recovery and mid- to long-term continence.

    PubMed

    Furrer, Marc A; Vilaseca, Antoni; Corradi, Renato B; Boxler, Silvan; Thalmann, George N; Nguyen, Daniel P

    2018-06-01

    A growing number of men undergo repeat biopsies prior to radical prostatectomy for prostate cancer. However, the long-term impact of repeat biopsies on functional outcomes in this patient population remains unelucidated. Thus, we compared functional outcomes between patients who underwent single biopsy versus repeat biopsies before radical prostatectomy. From 1996 to 2015, 1015 consecutive patients underwent radical prostatectomy, and subsequently had urinary continence and erectile function assessed for >2 years follow-up. One-fourth of patients (275; 27%) had ≥2 biopsies before prostatectomy. Logistic regression models tested whether repeat biopsy before prostatectomy predicted continence or erectile function recovery. For the overall cohort, continence rates were 84%, 92%, 96%, and 98% at 3, 6, 12, and 24 months, respectively. Repeat biopsy before prostatectomy was associated with lower continence rate at 3 months compared to single biopsy (P = 0.03); however, no significant differences were observed at 6, 12, or 24 months. In multivariable analyses adjusting for age, body mass index and diabetes/cardiovascular disease/smoking, the association between repeat biopsy and lower likelihood of continence at 3 months remained (odds ratio 0.67, 95% confidence interval 0.47-0.97; P = 0.03). Overall erectile function recovery rates were 16%, 33%, 51%, and 55% at 3, 6, 12, and 24 months, respectively. No difference in erectile function recovery rates was seen at any time point for single biopsy versus repeat biopsy. In multivariable analyses, repeat biopsy was not predictive of erectile function recovery at any time point. Repeat biopsy before radical prostatectomy impairs early continence after surgery. However, erectile function recovery and mid-term to long-term continence are not affected. These data support the current trend towards active surveillance and delayed local treatment in patients with low- to intermediate-risk prostate cancer. © 2018 Wiley

  3. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Continued to solicit industry research partners to provide test sites. A Cooperative Research Agreement has been signed with Oneok, for a test site in the Mocane-Laverne field in the Anadarko basin (Oklahoma). The site

  4. CO2 Fluxes Associated with Soil Organic C Stock Changes in the Mid-Continent Region of the U.S.

    NASA Astrophysics Data System (ADS)

    Ogle, S. M.; Paustian, K.; Easter, M.; Killian, K.; Williams, S.

    2005-12-01

    Regional CO2 sources and sinks need to be quantified in the terrestrial biosphere for basic understanding and policy development. Our objective was to quantify CO2 fluxes for the Mid-Continent Region of the US, including Iowa and neighboring areas in adjacent states, using a "bottom-up" simulation modeling approach. Soils represent an important potential sink for this largely agricultural region because of limited potential for CO2 uptake and storage in woody biomass. SOC stocks were estimated to have increased during the 1990s at a rate equivalent to 3.81 Tg CO2 yr-1, but with considerable sub-regional variation due to differences in land use and management patterns. Sinks were driven by conservation tillage adoption, enrollment in the Conservation Reserve Program, and conversion of annual crops to continuous hay or pasture. The dominant source of CO2 from soils in the Mid-Continent Region was attributed to drainage and cultivation of organic soils. Uncertainties in regional estimates were determined using a Monte Carlo Analysis and empirically-based uncertainty estimator, and the largest uncertainties were associated with estimating the fluxes from drained organic soils. A major research challenge is to verify the accuracy of these rates using "top-down" atmospheric budgets that are independent of the bottom-up inventory.

  5. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Prepared various materials to describe the project for promotional purposes and to attract potential industry partners. Materials included slides for DOE's displays at the SPE Eastern Regional and Annual Technical

  6. A volcanic connection between the Pennsylvanian of the Mid-Continent and Appalachian regions

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lyons, P.C.; Congdon, R.D.; Outerbridge, W.F.

    1993-02-01

    Until now, it has not been possible to find key beds that precisely connect the Pennsylvanian section in the Mid-Continent and Appalachian regions. Altered volcanic ash deposits (tonsteins) offer the potential for high-precision stratigraphic correlation. The Fire Clay tonstein which is chemically distinct from the other five Middle Pennsylvanian tonstein beds in the central Appalachian basin, has a unimodal, rhyolitic fingerprint'' based on glass-inclusion data (n = 109) from volcanic quartz. This tonstein has been correlated over a distance of about 400 km in KY, WV, VA, and TN. Analyses of glass inclusions (n = 12) in volcanic quartz frommore » a mixed-layer (illite/smectite) tonstein (K-bentonite) from near the Morrowan-Atokan boundary, recovered from cuttings in Arkansas wells (Phillips Petroleum Co., [number sign]2, Johnson City; Carter Oil Co., [number sign]1 Williams, Conway City), are identical, within the limits of analytical precision, to those from the Fire Clay tonstein.« less

  7. Linearity of Mid-Continent Kimberlite-Carbonatite Magmatism, USA: Slab-Edge Focus as Alternative to Hot-Spot Track

    NASA Astrophysics Data System (ADS)

    Duke, G. I.; Carlson, R. W.

    2009-12-01

    The fates of subducted oceanic slabs at depth in the mantle are not well known, but linear trends of unusual magmatic products such as kimberlites and carbonatites might be used to track their past existence within the mantle. A N40°W linear trend of kimberlites and carbonatites, and rocks of kimberlitic affinity, from the Black Hills (WY-SD) to Alberta, was suggested to have been caused by upwelling mantle material focused directly above the western edge of the subducted Kula plate stalled in the transition zone, with a slab window or “tear” to the southwest (Duke, 2009). In contrast, a linear zone of similar magmas to the south (a southerly extension of this N40°W linear trend, from Kansas to Louisiana) has been proposed to represent a hot spot trace produced by a mantle plume (“Bermuda Hot Spot”). Ongoing studies of ages and geochemistry of alkalic rocks along the N40°W trend from Louisiana to Alberta provide increasing evidence for a slab-edge model as the cause of the linear trend of kimberlites and carbonatites in the mid-continent. In addition, seismic tomography indicates that the torn Farallon slab currently is stalled in the transition zone below the mid-continent, and an older slab is within the lower mantle farther to the east (Sigloch et al., 2008). These seismic data were interpreted as revealing the presence of the western edge of the Farallon plate trending roughly N40°W. The slab edge as projected to the surface is parallel to, but slightly west of, the trend of kimberlites and carbonatites at the mid-continent. Recently published ages show no clear age progression for the magmatism and thus do not support a hot-spot hypothesis for the linear trend. The isotopic compositions of the alkalic rocks show a genetic similarity among more recent magmas along the trend. There are at least four main pulses of magmatism along the trend at 110-85, 67-64, 55-52, and less than 50 Ma. Kimberlites and carbonatites in the northern section of the N40

  8. An assessment of stressor extent and biological condition in the North American mid-continent great rivers (USA)

    USGS Publications Warehouse

    Angradi, Ted R.; Bolgriend, David W.; Jicha, Terri M.; Pearson, Mark S.; Taylor, Debra L.; Moffett, Mary F.; Blocksom, Karen A.; Walters, David M.; Elonen, Colleen M.; Anderson, Leroy E.; Lazorchak, James M.; Reavie, Euan D.; Kireta, Amy R.; Hill, Brian H.

    2011-01-01

    We assessed the North American mid-continent great rivers (Upper Mississippi, Missouri, and Ohio). We estimated the extent of each river in most- (MDC) or least-disturbed condition (LDC) based on multiple biological response indicators: fish and macroinvertebrate, trophic state based on chlorophyll a, macrophyte cover, and exposure of fish-eating wildlife to toxic contaminants in fish tissue (Hg, total chlordane, total DDT, PCBs). We estimated the extent of stressors on each river including nutrients, suspended solids, sediment toxicity, invasive species, and land use (agriculture and impervious surface). All three rivers had a greater percent of their river length in MDC than in LDC based on fish assemblages. The Upper Mississippi River had the greatest percent of river length with eutrophic status. The Ohio River had the greatest percent of river length with fish with tissue contaminant levels toxic to wildlife. Overall, condition indices based on fish assemblages were more sensitive to stress than macroinvertebrate indices. Compared to the streams in its basin, more of the Upper Mississippi and Missouri Rivers were in MDC for nutrients than the Ohio River. Invasive species (Asian carp and Dreissenid mussels) were less widespread and less abundant on the Missouri River than on the other great rivers. The Ohio River had the most urbanized floodplains (greatest percent impervious surface). The Missouri River had the most floodplain agriculture. The effect of large urban areas on river condition was apparent for several indicators. Ecosystem condition based in fish assemblages, trophic state, and fish tissue contamination was related to land use on the floodplain and at the subcatchment scale. This is the first unbiased bioassessment of the mid-continent great rivers in the United States. The indicators, condition thresholds, results, and recommendations from this program are a starting point for improved future great river assessments.

  9. Origin and development of plains-type folds in the mid-continent (United States) during the late Paleozoic

    USGS Publications Warehouse

    Merriam, D.F.

    2005-01-01

    Plains-type folds are local, subtle anticlines formed in the thin sedimentary package overlying a shallow, crystalline basement on the craton. They are small in areal extent (usually less than 1-3 km 2 [0.4-1.2 mi2]), and their amplitude increases with depth (usually tens of meters), which is mainly the result of differential compaction of sediments (usually clastic units) over tilted, rigid, basement fault blocks. The development of these structural features by continuous but intermittent movement of the basement fault blocks in the late Paleozoic in the United States mid-continent is substantiated by a record of stratigraphic and sedimentological evidence. The recurrent structural movement, which reflects adjustment to external stresses, is expressed by the change in thickness of stratigraphic units over the crest of the fold compared to the flanks. By plotting the change in thickness for different stratigraphic units of anticlines on different fault blocks, it is possible to determine the timing of movement of the blocks that reflect structural adjustment. These readjustments are confirmed by sedimentological evidence, such as convolute, soft-sediment deformation features and small intraformational faults. The stratigraphic interval change in thickness for numerous structures in the Cherokee, Forest City, and Salina basins and on the Nemaha anticline of the mid-continent United States was determined and compared for location and timing of the adjustments. Most of the adjustment occurred during and after time of deposition of the Permian-Pennsylvanian clastic units, which, in turn, reflect tectonic disturbance in adjacent areas, and the largest amount of movement on the plains-type structures occurred on those nearest and semiparallel to major positive features, such as the Nemaha anticline. Depending on the time of origin and development of plains-type folds, they may control the entrapment and occurrence of oil and gas. Copyright ??2005. The American

  10. Modeling and Synthesis Support for the North American Carbon Program

    NASA Astrophysics Data System (ADS)

    Baskaran, L.; Cook, R. B.; Thornton, P. E.; Post, W. M.; Wilson, B. E.; Dadi, U.

    2007-12-01

    The Modeling and Synthesis Thematic Data Center (MAST-DC) supports the North American Carbon Program by providing data products and data management services needed for modeling and synthesis activities. The overall objective of MAST-DC is to provide advanced data management support to NACP investigators doing modeling and synthesis, thereby freeing those investigators from having to perform data management functions. MAST-DC has compiled a number of data products for North America, including sub-pixel land-water content, daily meteorological data, and soil, land cover, and elevation data. In addition, we have developed an internet-based WebGIS system that enables users to browse, query, display, subset, and download spatial data using a standard web browser. For the mid-continent intensive, MAST-DC is working with a group of data assimilation modelers to generate a consistent set of meteorological data to drive bottom-up models.

  11. Dynamic magnetic resonance imaging of the behavior of the mid-urethra in healthy and stress incontinent women.

    PubMed

    Rinne, Kirsi Marja; Kainulainen, Sakari; Aukee, Sinikka; Heinonen, Seppo; Nilsson, Carl Gustaf

    2010-03-01

    Support of the mid-urethra is thought to be an essential element of urinary continence in the female. Our aim was to image the behavior of the mid-urethra in healthy volunteers and in stress urinary incontinence (SUI) patients by dynamic magnetic resonance imaging (MRI). Prospective study. Gynecology outpatient clinic association with Department of Radiology in University Hospital of Kuopio, Finland. Fifteen healthy volunteers and 40 SUI women underwent dynamic MRI at rest, during pelvic floor muscle contraction, coughing and voiding with a bladder volume of 200 ml. Our aim was to determine the precise location and movement of the mid-urethra during these activities. The co-ordinate location and movement of the mid-urethra. Continent volunteers can elevate their mid-urethra significantly higher than incontinent women. Moreover, the mid-urethra of incontinent women rotated significantly more dorsocaudally during straining and coughing than in continent women. Elevation of the mid-urethra was more marked in continent compared to urinary incontinent women on pelvic floor muscle contraction suggesting sufficient support of the urethra. Downward movement of the mid-urethra was more significant in stress incontinent women than in continent volunteers.

  12. A Surface Wave's View of the Mid-Continent Rift

    NASA Astrophysics Data System (ADS)

    Foster, A. E.; Darbyshire, F. A.; Schaeffer, A. J.

    2017-12-01

    The presence of the Mid-Continent Rift (MCR), a 1.1Ga failed rift in central North America, raises many questions. We address the following: what lasting effects has it had on the continental lithosphere? Though many studies have looked at the area with a variety of data types, the combination of USArray Transportable Array stations to the south, permanent and temporary Canadian stations to the north, and SPREE stations in strategic locations crossing the rift provide a new opportunity for a regional surface-wave study. We select 80 stations with roughly 200 km spacing, resulting in dense path coverage of a broad area centered on the MCR. We use teleseismic data for all earthquakes from January 2005-August 2016 with a magnitude greater than 6.0, amounting to over 1200 events, and we make Rayleigh wave two-station dispersion measurements for all station pairs with suitable event-station geometry. We invert these measurements for anisotropic phase-velocity maps at periods of 20-200 s, yielding information not only on the wave speed but also the current fabric of the lithosphere, a complicated record of strain from formation, through modification from orogeny, attempted rifting, and hotspot interaction, to present day plate motion. We observe a clear signature of the MCR at short (20-25 s) periods, with the slowest phase-velocity anomaly in the region aligning with the strongest gravity anomaly. At increasing periods, and thus greater depths, this slowest anomaly shifts to beneath the center of Lake Superior (30-40 s). Eventually, it appears to merge with a slow anomaly to the north associated with the Nipigon Embayment, and contrasts sharply with an adjacent fast anomaly in the western Superior Province. In our preliminary anisotropy results, we observe weak anisotropy at the latitude of the MCR and to the south, whereas to the north of the MCR we find strong anisotropy. This is similar to the spatial variations in magnitude of delay times from shear-wave splitting

  13. New model of succession of Middle and Late Pennsylvanian fossil communities in north Texas, Mid-Continent, and Appalachians with implications on black shale controversy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boardman, D.R. II; Yancey, T.E.; Mapes, R.H.

    1983-03-01

    A new model for the succession of Pennsylvanian fossil communities, preserved in cyclothems, is proposed on the basis of more than 200 fossil localities in the Mid-Continent, Appalachians, and north Texas. Early models for Mid-Continent cyclothems placed the black shales in shallow water, with maximum transgression at the fusulinid-bearing zone in the overlying limestone. The most recent model proposed that the black phosphatic shales, which commonly occur between two subtidal carbonates, are widespread and laterally continuous over great distances and represent maximum transgression. The black phosphatic shales contain: ammonoids; inarticulate brachiopods; radiolarians; conularids; shark material and abundant and diverse conodonts.more » The black shales grade vertically and laterally into dark gray-black shales which contain many of the same pelagic and epipelagic forms found in the phosphatic black shales. This facies contains the deepest water benthic community. Most of these forms are immature, pyritized, and generally are preserved as molds. The dark gray-black facies grades into a medium gray shale facies which contains a mature molluscan fauna. The medium gray shale grades into a lighter gray facies, which is dominated by brachiopods, crinoids, and corals, with occasional bivalves and gastropods. (These facies are interpreted as being a moderate to shallow depth shelf community). The brachiopid-crinoid community is succeeded by shallow water communities which may have occupied shoreline, lagoonal, bay, interdeltaic, or shallow prodeltaic environments.« less

  14. An intense radiation in mid-infrared of Xe

    NASA Astrophysics Data System (ADS)

    He, Shan; Liu, Dong; Guo, Jingwei; Sang, Fengting

    2017-01-01

    Recently, the optically pumped rare gas lasers have been attracted extensive attention. Rare gas laser systems with Ne (2p53p), Ar (3p54p), and Kr (4p55p) atoms have been investigated. However, there are sparse studies based on Xe. In this work, new phenomena, intensive mid-infrared amplified spontaneous emissions (ASEs), are found after two-photon excitation of Xe from the ground state to the 6p[1/2]0 state. Simultaneously, substantial 6p[1/2]1 atoms are populated. The thresholds of ASE peak 1 and the generation of 6p[1/2]1 atoms are both about 1.5 mJ. It indicates that there should exist the relationship between these two phenomena. The ASE signals show broadband spectra. Therefore, it must be yielded by the superposition of Xe2* excimer transitions. The mid-infrared ASEs lead to excimers correlating to the 6s'[1/2]1 enormously generated. Then these excimers dissociate to produce substantial 6p[1/2]1 atoms. Under some circumstance, the ratio of the 6p[1/2]1 to 6p[1/2]0 atoms reaches about 80%. It indicates that the 6p[1/2]0 atoms strongly tend to decay through the emissions between the excimer states. Using these emissions, continuous-tunable mid-infrared laser with metastable Xe can be promisingly produced.

  15. The continent-ocean transition at the mid-northern margin of the South China Sea

    NASA Astrophysics Data System (ADS)

    Gao, Jinwei; Wu, Shiguo; McIntosh, Kirk; Mi, Lijun; Yao, Bochu; Chen, Zeman; Jia, Liankai

    2015-07-01

    The northern margin of the South China Sea (SCS) has particular structural and stratigraphic characteristics that are somewhat different from those described in typical passive margin models. The differences are attributable to poly-phase tectonic movements and magmatic activity resulting from the interaction among the Eurasian, Philippine Sea and Indo-Australian plates. Based on several crustal-scale multi-channel seismic reflection profiles and satellite gravity data across the northern SCS margin, this paper analyzes the structures, volcanoes and deep crust of the continent-ocean transition zone (COT) at the mid-northern margin of the SCS to study the patterns and model of extension there. The results indicate that the COT is limited landward by basin-bounding faults near Baiyun sag and is bounded by seaward-dipping normal faults near the oceanic basin in our seismic lines. The shallow anatomy of the COT is characterized by rift depression, structural highs with igneous rock and/or a volcanic zone or a zone of tilted fault blocks at the distal edge. Gravity modeling revealed that a high velocity layer (HVL) with a 0.8-6-km thickness is frequently present in the slope below the lower crust. Our study shows that the HVL is only located in the eastern portion of the northern SCS margin based on the available geophysical data. We infer from this that the presence of an HVL is not required in the COT at the northern SCS margin. The magmatic intrusions and HVL may be related to partial melting caused by the decompression of a passive, upwelling asthenosphere, which resulted primarily in post-rifting underplating and magmatic emplacement or modification of the crust. Based on this study, we propose that an intermediate mode of rifting was active in the mid-northern margin of the SCS with characteristics that are closer to those of the magma-poor margins than those of volcanic margins.

  16. Generation and multi-octave shaping of mid-infrared intense single-cycle pulses

    NASA Astrophysics Data System (ADS)

    Krogen, Peter; Suchowski, Haim; Liang, Houkun; Flemens, Noah; Hong, Kyung-Han; Kärtner, Franz X.; Moses, Jeffrey

    2017-03-01

    The generation of intense mid-infrared (mid-IR) optical pulses with customizable shape and spectra spanning a multiple-octave range of vibrational frequencies is an elusive technological capability. While some recent approaches to mid-IR supercontinuum generation—such as filamentation, multicolour four-wave-mixing and optical rectification—have successfully generated broad spectra, no process has been identified for achieving complex pulse shaping at the generation step. The adiabatic frequency converter allows for a one-to-one transfer of spectral phase through nonlinear frequency conversion over a larger-than-octave-spanning range and with an overall linear phase transfer function. Here, we show that we can convert shaped near-infrared (near-IR) pulses to shaped, energetic, multi-octave-spanning mid-IR pulses lasting only 1.2 optical cycles, and extendable to the sub-cycle regime. We expect this capability to enable a new class of precisely controlled nonlinear interactions in the mid-IR spectral range, from nonlinear vibrational spectroscopy to strong light-matter interactions and single-shot remote sensing.

  17. Middle Holocene Changes in Midwestern Precipitation Intensity Captured by Indiana Stalagmites

    NASA Astrophysics Data System (ADS)

    Akers, P. D.; Brook, G. A.; Liang, F.; Cheng, H.; Edwards, R. L.

    2017-12-01

    Three stalagmites collected from Upper Porter Cave in southern Indiana provide a record of Midwestern hydroclimate changes for the period 2.3-8.4 ka BP. Our record spans the Middle Holocene, known as a time of mid-continental drying for North America and used as an analog for warmer future climates. The spatial extent of this drying is not well constrained, and some eastern North American records show wetter conditions coinciding with the drying of the continental interior. Southern Indiana is located on the eastern periphery of mid-continental North America, and our stalagmite records can help constrain the eastern extent of drying. Upper Porter Cave floods easily during heavy rain events, and modern observations suggest frequent cave flooding prevents stalagmite growth. Thus, we view periods of stalagmite growth as a proxy for a less intense and possibly drier precipitation regime that limits cave flooding. All three stalagmites began growing 8.4 ka BP and stopped growing 7.5 ka BP. This hiatus at 7.5 ka BP is associated with laminae dissolution and greater sediment incorporation (see image), supporting increased precipitation intensity and cave flooding at this time. This contrasts with concurrent drying in the mid-continent and suggests a Middle Holocene with a steeper east-west precipitation gradient than present. This period of greater precipitation intensity extended until 4.9 ka BP when one stalagmite re-initiated growth, possibly due to mid-continental dryness expanding eastward into southern Indiana. This renewed growth was intermittent at 4.7-4.9, 3.6-4.2, and 2.3-3.1 ka BP, and multi-century flood-driven hiatuses separate these drier periods. A more intense precipitation regime that lasts until present provoked final growth cessation at 2.3 ka BP. Combined with other regional hydroclimate records, our stalagmite suggests that the transition from the Middle to Late Holocene was a period of unstable precipitation regimes for the eastern mid-continent

  18. On the mid-latitude ionospheric storm association with intense geomagnetic storms

    NASA Astrophysics Data System (ADS)

    Okpala, Kingsley Chukwudi; Ogbonna, Chinasa Edith

    2018-04-01

    The bulk association between ionospheric storms and geomagnetic storms has been studied. Hemispheric features of seasonal variation of ionospheric storms in the mid-latitude were also investigated. 188 intense geomagnetic storms (Dst ≤ 100 nT) that occurred during solar cycles 22 and 23 were considered, of which 143 were observed to be identified with an ionospheric storm. Individual ionospheric storms were identified as maximum deviations of the F2 layer peak electron density from quiet time values. Only ionospheric storms that could clearly be associated with the peak of a geomagnetic storm were considered. Data from two mid-latitude ionosonde stations; one in the northern hemisphere (i.e. Moscow) and the other in the southern hemisphere (Grahamstown) were used to study ionospheric conditions at the time of the individual geomagnetic storms. Results show hemispheric and latitudinal differences in the intensity and nature of ionospheric storms association with different types of geomagnetic storms. These results are significant for our present understanding of the mechanisms which drive the changes in electron density during different types of ionospheric storms.

  19. The Continent-Ocean Transition in the Mid-Norwegian Margin: Insight From Seismic Data and the Onshore Caledonian Analogue in the Seve Nappe Complex

    NASA Astrophysics Data System (ADS)

    Abdelmalak, Mansour M.; Planke, Sverre; Andersen, Torgeir B.; Faleide, Jan Inge; Corfu, Fernando; Tegner, Christian; Myklebust, Reidun

    2015-04-01

    The continental breakup and initial seafloor spreading in the NE Atlantic was accompanied by widespread intrusive and extrusive magmatism and the formation of conjugate volcanic passive margins. These margins are characterized by the presence of seaward dipping reflectors (SDR), an intense network of mafic sheet intrusions of the continental crust and adjacent sedimentary basins and a high-velocity lower crustal body. Nevertheless many issues remain unclear regarding the structure of volcanic passive margins; in particular the transitional crust located beneath the SDR.New and reprocessed seismic reflection data on the Mid-Norwegian margin allow a better sub-basalt imaging of the transitional crust located beneath the SDR. Different high-amplitude reflections with abrupt termination and saucer shaped geometries are identified and interpreted as sill intrusions. Other near vertical and inclined reflections are interpreted as dykes or dyke swarms. We have mapped the extent of the dyke reflections along the volcanic margin. The mapping suggests that the dykes represent the main feeder system for the SDR. The identification of saucer shaped sills implies the presence of sediments in the transitional zone beneath the volcanic sequences. Onshore exposures of Precambrian basement of the eroded volcanic margin in East Greenland show that, locally, the transitional crust is highly intruded by dykes and intrusive complexes with an increasing intensity of the plumbing and dilatation of the continental crust ocean-ward. Another well exposed analogue for a continent-ocean transitional crust is located within the Seve Nappe Complex (SNC) of the Scandinavian Caledonides. The best-preserved parts of SNC in the Pårte, Sarek, Kebnekaise, Abisko, and Indre Troms mountains are composed mainly of meta-sandstones and shales (now hornfelses) truncated typically by mafic dykes. At Sarek and Pårte, the dykes intrude the sedimentary rocks of the Favoritkammen Group, with a dyke density up

  20. The effects of ipsilateral, contralateral, and bilateral broadband noise on the mid-level hump in intensity discriminationa)

    PubMed Central

    Roverud, Elin; Strickland, Elizabeth A.

    2015-01-01

    Previous psychoacoustical and physiological studies indicate that the medial olivocochlear reflex (MOCR), a bilateral, sound-evoked reflex, may lead to improved sound intensity discrimination in background noise. The MOCR can decrease the range of basilar-membrane compression and can counteract effects of neural adaptation from background noise. However, the contribution of these processes to intensity discrimination is not well understood. This study examined the effect of ipsilateral, contralateral, and bilateral noise on the “mid-level hump.” The mid-level hump refers to intensity discrimination Weber fractions (WFs) measured for short-duration, high-frequency tones which are poorer at mid levels than at lower or higher levels. The mid-level hump WFs may reflect a limitation due to basilar-membrane compression, and thus may be decreased by the MOCR. The noise was either short (50 ms) or long (150 ms), with the long noise intended to elicit the sluggish MOCR. For a tone in quiet, mid-level hump WFs improved with ipsilateral noise for most listeners, but not with contralateral noise. For a tone in ipsilateral noise, WFs improved with contralateral noise for most listeners, but only when both noises were long. These results are consistent with MOCR-induced WF improvements, possibly via decreases in effects of compression and neural adaptation. PMID:26627798

  1. On the wall perturbation correction for a parallel-plate NACP-02 chamber in clinical electron beams.

    PubMed

    Zink, K; Wulff, J

    2011-02-01

    In recent years, several Monte Carlo studies have been published concerning the perturbation corrections of a parallel-plate chamber in clinical electron beams. In these studies, a strong depth dependence of the relevant correction factors (p(wall) and P(cav)) for depth beyond the reference depth is recognized and it has been shown that the variation with depth is sensitive to the choice of the chamber's effective point of measurement. Recommendations concerning the positioning of parallel-plate ionization chambers in clinical electron beams are not the same for all current dosimetry protocols. The IAEA TRS-398 as well as the IPEM protocol and the German protocol DIN 6800-2 interpret the depth of measurement within the phantom as the water equivalent depth, i.e., the nonwater equivalence of the entrance window has to be accounted for by shifting the chamber by an amount deltaz. This positioning should ensure that the primary electrons traveling from the surface of the water phantom through the entrance window to the chamber's reference point sustain the same energy loss as the primary electrons in the undisturbed phantom. The objective of the present study is the determination of the shift deltaz for a NACP-02 chamber and the calculation of the resulting wall perturbation correction as a function of depth. Moreover, the contributions of the different chamber walls to the wall perturbation correction are identified. The dose and fluence within the NACP-02 chamber and a wall-less air cavity is calculated using the Monte Carlo code EGSnrc in a water phantom at different depths for different clinical electron beams. In order to determine the necessary shift to account for the nonwater equivalence of the entrance window, the chamber is shifted in steps deltaz around the depth of measurement. The optimal shift deltaz is determined from a comparison of the spectral fluence within the chamber and the bare cavity. The wall perturbation correction is calculated as the ratio

  2. Crustal Properties Across the Mid-Continent Rift via Transfer Function Analysis

    NASA Astrophysics Data System (ADS)

    Frederiksen, A. W.; Tyomkin, Y.; Campbell, R.; van der Lee, S.; Zhang, H.

    2015-12-01

    The Mid-Continent Rift (MCR), a failed Proterozoic rift structure in central North America, is a dominant feature of North American gravity maps. The rift underwent a combination of extension, magmatism, and later compression, and it is difficult to predict how these events affected the overall crustal thickness and bulk composition in the vicinity of the rift axis, though the associated gravity high indicates that large-volume mafic magmatism took place. The Superior Province Rifting Earthscope Experiment (SPREE) project instrumented the MCR with Flexible Array broadband seismographs from 2011 through 2013 in Minnesota and Wisconsin, along two lines crossing the rift axis as well as a line following the axis. We examine teleseismic P-coda data from SPREE and nearby Transportable Array instruments using a new technique: transfer-function analysis. In this approach, possible models of crustal structure are used to generate a predicted transfer function relating the radial and vertical components of the P coda at a particular site. The transfer function then allows generation of a misfit (between the true radial component and a synthetic radial component predicted from the vertical trace) without the need to perform receiver-function deconvolution, thus avoiding the deconvolution problems encountered with receiver functions in sedimentary basins. We use the transfer-function approach to perform a grid search over three crustal properties: crustal thickness, crustal P/S velocity ratio, and the thickness of an overlying sedimentary basin. Results for our SPREE/TA data set indicate that the crust is significantly thickened along the rift axis, with maximum thicknesses approaching 50 km; the crust is thinner (ca. 40 km) outside of the rift zone. The crustal thickness structure is particularly complex beneath southeastern Minnesota, where very strong Moho topography is present, as well as up to 2 km of sediment; further north, the Moho is smoother and the basin is not

  3. Air kerma calibration factors and chamber correction values for PTW soft x-ray, NACP and Roos ionization chambers at very low x-ray energies.

    PubMed

    Ipe, N E; Rosser, K E; Moretti, C J; Manning, J W; Palmer, M J

    2001-08-01

    This paper evaluates the characteristics of ionization chambers for the measurement of absorbed dose to water using very low-energy x-rays. The values of the chamber correction factor, k(ch), used in the IPEMB 1996 code of practice for the UK secondary standard ionization chambers (PTW type M23342 and PTW type M23344), the Roos (PTW type 34001) and NACP electron chambers are derived. The responses in air of the small and large soft x-ray chambers (PTW type M23342 and PTW type M23344) and the NACP and Roos electron ionization chambers were compared. Besides the soft x-ray chambers, the NACP and Roos chambers can be used for very low-energy x-ray dosimetry provided that they are used in the restricted energy range for which their response does not change by more than 5%. The chamber correction factor was found by comparing the absorbed dose to water determined using the dosimetry protocol recommended for low-energy x-rays with that for very low-energy x-rays. The overlap energy range was extended using data from Grosswendt and Knight. Chamber correction factors given in this paper are chamber dependent, varying from 1.037 to 1.066 for a PTW type M23344 chamber, which is very different from a value of unity given in the IPEMB code. However, the values of k(ch) determined in this paper agree with those given in the DIN standard within experimental uncertainty. The authors recommend that the very low-energy section of the IPEMB code is amended to include the most up-to-date values of k(ch).

  4. Observations by Mid-continent Magnetoseismic Chain (McMAC) and their use in space weather research

    NASA Astrophysics Data System (ADS)

    Chi, P. J.; McMac Team

    The Mid-continent Magnetoseismic Chain McMAC consists of nine magnetometer stations that line up across the U S and Mexico along the 330th magnetic meridian These systems sample at 2 Hz and monitor the fluctuations of the geomagnetic field caused by space weather phenomena and they are always on the Internet to allow rapid access of data The McMAC stations can connect to the Fort Churchill Line of the CARISMA Array and two IGPP-LANL stations at the same longitude and form a long magnetometer chain that spans the L-value range from 1 3 to 11 7 the greatest latitudinal coverage in all meridians One of the main advantages of this magnetometer chain is its close separation between adjacent stations enabling the use of the gradient technique to identify field line resonance FLR frequencies and to further estimate the plasma mass density in the magnetosphere The observations of FLR and the derived density can always be collected in the daytime and occasionally in the nighttime as well In this paper we present the observations by the newly completed McMAC and jointly by the CARISMA and IGPP-LANL Arrays The observed plasma density and its wide coverage in L-value can benefit space weather studies such as on magnetosphere-ionosphere coupling and on the wave-particle interaction for modeling the radiation belts Also discussed are other applications of the McMAC observations in space weather research including possible joint observations with satellite missions

  5. Spreading continents kick-started plate tectonics.

    PubMed

    Rey, Patrice F; Coltice, Nicolas; Flament, Nicolas

    2014-09-18

    Stresses acting on cold, thick and negatively buoyant oceanic lithosphere are thought to be crucial to the initiation of subduction and the operation of plate tectonics, which characterizes the present-day geodynamics of the Earth. Because the Earth's interior was hotter in the Archaean eon, the oceanic crust may have been thicker, thereby making the oceanic lithosphere more buoyant than at present, and whether subduction and plate tectonics occurred during this time is ambiguous, both in the geological record and in geodynamic models. Here we show that because the oceanic crust was thick and buoyant, early continents may have produced intra-lithospheric gravitational stresses large enough to drive their gravitational spreading, to initiate subduction at their margins and to trigger episodes of subduction. Our model predicts the co-occurrence of deep to progressively shallower mafic volcanics and arc magmatism within continents in a self-consistent geodynamic framework, explaining the enigmatic multimodal volcanism and tectonic record of Archaean cratons. Moreover, our model predicts a petrological stratification and tectonic structure of the sub-continental lithospheric mantle, two predictions that are consistent with xenolith and seismic studies, respectively, and consistent with the existence of a mid-lithospheric seismic discontinuity. The slow gravitational collapse of early continents could have kick-started transient episodes of plate tectonics until, as the Earth's interior cooled and oceanic lithosphere became heavier, plate tectonics became self-sustaining.

  6. OxyContin

    MedlinePlus

    ... Careers Our People Staff Volunteers Board of Directors Science Advisory Board Newsroom Annual Report & Financials Frequently Asked Questions Contact Search for: Search Home Drug Guide OxyContin OxyContin Know the facts about and OxyContin connect with help and support ...

  7. Rayleigh Wave Tomography of Mid-Continent Rift (MCR) using Earthquake and Ambient Noise Data

    NASA Astrophysics Data System (ADS)

    Aleqabi, G. I.; Wiens, D.; Wysession, M. E.; Shen, W.; van der Lee, S.; Revenaugh, J.; Frederiksen, A. W.; Darbyshire, F. A.; Stein, S. A.; Jurdy, D. M.; Wolin, E.; Bollmann, T. A.

    2015-12-01

    The structure of the North American Mid-Continent Rift Zone (MCRZ) is examined using Rayleigh waves from teleseismic earthquakes and ambient seismic noise recorded by the Superior Province Rifting EarthScope Experiment (SPREE). Eighty-four broadband seismometers were deployed during 2011-2013 in Minnesota and Wisconsin, USA, and Ontario, CA, along three lines; two across the rift axis and the third along the rift axis. These stations, together with the EarthScope Transportable Array, provided excellent coverage of the MCRZ. The 1.1 Ga Mesoproterozoic failed rift consists of two arms, buried under post-rifting sedimentary formations that meet at Lake Superior. We compare two array-based tomography methods using teleseismic fundamental mode Rayleigh waves phase and amplitude measurements: the two-plane wave method (TPWM, Forsyth, 1998) and the automated surface wave phase velocity measuring system (ASWMS, Jin and Gaherty, 2015). Both array methods and the ambient noise method give relatively similar results showing low velocity zones extending along the MCRZ arms. The teleseismic Rayleigh wave results from 18 - 180 s period are combined with short period phase velocity results (period 8-30 s) obtained from ambient noise by cross correlation. Phase velocities from the methods are very similar at periods of 18-30 where results overlap; in this period range we use the average of the noise and teleseismic results. Finally the combined phase velocity curve is inverted using a Monte-Carlo inversion method at each geographic point in the model. The results show low velocities at shallow depths (5-10 km) that are the result of very deep sedimentary fill within the MCRZ. Deeper-seated low velocity regions may correspond to mafic underplating of the rift zone.

  8. More Intense Mega Heat Waves in the Warmer World

    NASA Astrophysics Data System (ADS)

    Choi, G.; Robinson, D. A.

    2017-12-01

    In this study, changes in the occurrences of heat waves on the globe since the mid- 20th century and the synoptic characteristics of mega heat waves at regional scales in the warmer climate are examined. The NCEP-NCAR reanalysis surface data show that there have been no obvious linear changes in the heat wave frequencies at the continental scales since the mid-20th century, but amplified interdecadal variations led to unprecedented intense heat waves in the recent decades at the regional scales. Such mega heat waves have been more frequently observed in the poleward subtropical climate belts as well as in the interior region of continents. According to the analyses of upper tropospheric data, the occurrences of more intense mega heat waves since the late 20th century may be associated with the expansion of subtropical high pressures. These results suggest that populous cities near the subtropical climate zones should provide proactive mega heat wave warning systems for residents due to their vulnerability to the sudden attack of human lives harvest by mega heat waves in the warmer 21st century.

  9. Ancient Continental Lithosphere Dislocated Beneath Ocean Basins Along the Mid-Lithosphere Discontinuity: A Hypothesis

    NASA Astrophysics Data System (ADS)

    Wang, Zhensheng; Kusky, Timothy M.; Capitanio, Fabio A.

    2017-09-01

    The documented occurrence of ancient continental cratonic roots beneath several oceanic basins remains poorly explained by the plate tectonic paradigm. These roots are found beneath some ocean-continent boundaries, on the trailing sides of some continents, extending for hundreds of kilometers or farther into oceanic basins. We postulate that these cratonic roots were left behind during plate motion, by differential shearing along the seismically imaged mid-lithosphere discontinuity (MLD), and then emplaced beneath the ocean-continent boundary. Here we use numerical models of cratons with realistic crustal rheologies drifting at observed plate velocities to support the idea that the mid-lithosphere weak layer fostered the decoupling and offset of the African continent's buoyant cratonic root, which was left behind during Meso-Cenozoic continental drift and emplaced beneath the Atlantic Ocean. We show that in some cratonic areas, the MLD plays a similar role as the lithosphere-asthenosphere boundary for accommodating lateral plate tectonic displacements.

  10. Sub-cycle steering of the deprotonation of acetylene by intense few-cycle mid-infrared laser fields.

    PubMed

    Li, H; Kling, Nora G; Gaumnitz, T; Burger, C; Siemering, R; Schötz, J; Liu, Q; Ban, L; Pertot, Y; Wu, J; Azzeer, A M; de Vivie-Riedle, R; Wörner, H J; Kling, M F

    2017-06-26

    Directional breaking of the C-H/C-D molecular bond is manipulated in acetylene (C 2 H 2 ) and deuterated acetylene (C 2 D 2 ) by waveform controlled few-cycle mid-infrared laser pulses with a central wavelength around 1.6 μm at an intensity of about 8 × 10 13 W/cm 2 . The directionality of the deprotonation of acetylene is controlled by changing the carrier-envelope phase (CEP). The CEP-control can be attributed to the laser-induced superposition of vibrational modes, which is sensitive to the sub-cycle evolution of the laser waveform. Our experiments and simulations indicate that near-resonant, intense mid-infrared pulses permit a higher degree of control of the directionality of the reaction compared to those obtained in near-infrared fields, in particular for the deuterated species.

  11. Strong-field plasmonic photoemission in the mid-IR at <1 GW/cm² intensity.

    PubMed

    Teichmann, S M; Rácz, P; Ciappina, M F; Pérez-Hernández, J A; Thai, A; Fekete, J; Elezzabi, A Y; Veisz, L; Biegert, J; Dombi, P

    2015-01-12

    We investigated nonlinear photoemission from plasmonic films with femtosecond, mid-infrared pulses at 3.1 μm wavelength. Transition between regimes of multi-photon-induced and tunneling emission is demonstrated at an unprecedentedly low intensity of <1 GW/cm(2). Thereby, strong-field nanophysics can be accessed at extremely low intensities by exploiting nanoscale plasmonic field confinement, enhancement and ponderomotive wavelength scaling at the same time. Results agree well with quantum mechanical modelling. Our scheme demonstrates an alternative paradigm and regime in strong-field physics.

  12. [An alternative continence mechanism for continent catheterisable micturation].

    PubMed

    Honeck, P; Alken, P

    2010-01-01

    The creation of a stable, reliable, continent and easily catheterisable continence mechanism is an essential prerequisite for the construction of a continent cutaneous urinary reservoir. Although a substantial number of surgical methods has been described, construction is still a complex surgical procedure. The aim of this study was the evaluation of a new method for a continence mechanism using stapled small or large intestine. Small and large pig intestine was used for construction. For stapling the tube a 3 cm or 6 cm double row stapling system was used. Two variations using small and large intestine segments were constructed (IL 1, COL 1, COL 2). A 3 or 6 cm long stapler line was placed alongside a 12 Fr catheter positioned at the antimesenterial side creating a partially two-luminal segment. The open end of the non-catheterised lumen and the opposite intestinal end were closed by continuous sutures. The created tube was then embedded into the pouch. Pressure evaluation was performed for each variation. Intermittent external manual compression was used to simulate sudden pressure exposure. Construction times for the IL 1 and COL 1 variations were 10 +/- 1.5 min and 6.2 +/- 1.3 min for COL 2. All variations showed no leakage during filling or external compression. The maximum capacity was lower for the IL 1 compared to the COL variation. The maximum pressure levels reached did not differ significantly. The described technique is an easy and fast method to construct a continent and easy to catheterize continence mechanism using small or large intestine.

  13. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) The contract was signed on August 20, 2000. Little work has been performed other than preliminary planning to get the project underway.« less

  14. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Continued coordinating the final selection of candidates and field implementation with Oneok. Oneok plans on performing the operations early in 2003.« less

  15. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Finished preparing the final project report, less the field implementation component. Sent to DOE for review. (2) Continued coordinating the final selection of candidates and field implementation with Oneok. Oneok

  16. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Began preparing final project report, less the field implementation component. (2) Coordinated the final selection of candidates and field implementation with Oneok.« less

  17. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Completed both type curve and artificial neural network analysis of the field. Developed list of production enhancement candidates. (2) Made final presentation of results to Oneok in Tulsa (February 26). (3) Made

  18. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-04-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: Continued coordinating the final selection of candidates and field implementation with Oneok. Oneok plans on performing the operations early in 2003.« less

  19. Band Gap Distortion in Semiconductors Strongly Driven by Intense Mid-Infrared Laser Fields

    NASA Astrophysics Data System (ADS)

    Kono, J.; Chin, A. H.

    2000-03-01

    Crystalline solids non-resonantly driven by intense time-periodic electric fields are predicted to exhibit unusual band-gap distortion.(e.g., Y. Yacoby, Phys. Rev. 169, 610 (1968); L.C.M. Miranda, Solid State Commun. 45, 783 (1983); J.Z. Kaminski, Acta Physica Polonica A 83, 495(1993).) Such non-perturbative effects have not been observed to date because of the unavoidable sample damage due to the very high intensity required using conventional lasers ( 1 eV photon energy). Here, we report the first clear evidence of laser-induced bandgap shrinkage in semiconductors under intense mid-infrared (MIR) laser fields. The use of long-wavelength light reduces the required intensity and prohibits strong interband absorption, thereby avoiding the damage problem. The significant sub-bandgap absorption persists only during the existence of the MIR laser pulse, indicating the virtual nature of the effect. We show that this particular example of non-perturbative behavior, known as the dynamical Franz-Keldysh effect, occurs when the effective ponderomotive potential energy is comparable to the photon energy of the applied field. This work was supported by ONR, NSF, JST and NEDO.

  20. Review of Paleomagnetic Age Constraints of Mid-Continent Rift Strata, Upper Midwestern United States

    NASA Astrophysics Data System (ADS)

    Houlihan, E.; Runkel, A.; Feinberg, J. M.; Cowan, C. A.; Titus, S.

    2016-12-01

    (Malone et al., 2016). Here, we present new paleomagnetic data collected in 2015, and combine it with previous paleomagnetic studies to synthesize all paleomagnetic data on the Mid-Continent Rift strata and provide suggestions for future studies to determine the age and correlation of the units.

  1. An alternative continence tube for continent urinary reservoirs: evaluation of surgical technique, pressure and continence study in an ex-vivo model.

    PubMed

    Honeck, Patrick; Michel, Maurice Stephan; Trojan, Lutz; Alken, Peter

    2009-02-01

    Despite the large number of surgical techniques for continent cutaneous diversion described in literature, the creation of a reliable, continent and easily catheterizable continence mechanism remains a complex surgical procedure. Aim of this study was the evaluation of a new method for a catheterizable continence mechanism using stapled pig intestine. Small and large pig intestines were used for construction. A 3 or 6 cm double row stapling system was used. Three variations using small and large intestine segments were constructed. A 3 or 6 cm long stapler line was placed alongside a 12 Fr catheter positioned at the antimesenterial side creating a partially two-luminal segment. Construction time for the tube was measured. The created tube was then embedded into the pouch. Pressure evaluation of the continence mechanism was performed for each variation. Intermittent external manual compression was used to simulate sudden pressure exposure. All variations were 100% continent under filling volumes of up to 700 ml and pressure levels of 58 +/- 6 cm H(2)O for large intestine and 266 ml and 87 +/- 18 cm H(2)O for small intestine, respectively. With further filling above the mentioned capacity suture insufficiency occurred but no tube insufficiency. Construction time for all variations was less than 12 min. The described technique is an easy and fast method to construct a continence mechanism using small or large intestine. Our ex vivo experiments have shown sufficient continence situation in an ex-vivo model. Further investigations in an in-vivo model are needed to confirm these results.

  2. Mountain building processes during continent continent collision in the Uralides

    NASA Astrophysics Data System (ADS)

    Brown, D.; Juhlin, C.; Ayala, C.; Tryggvason, A.; Bea, F.; Alvarez-Marron, J.; Carbonell, R.; Seward, D.; Glasmacher, U.; Puchkov, V.; Perez-Estaun, A.

    2008-08-01

    Since the early 1990's the Paleozoic Uralide Orogen of Russia has been the target of a significant research initiative as part of EUROPROBE and GEODE, both European Science Foundation programmes. One of the main objectives of these research programmes was the determination of the tectonic processes that went into the formation of the orogen. In this review paper we focus on the Late Paleozoic continent-continent collision that took place between Laurussia and Kazakhstania. Research in the Uralides was concentrated around two deep seismic profiles crossing the orogen. These were accompanied by geological, geophysical, geochronological, geochemical, and low-temperature thermochronological studies. The seismic profiles demonstrate that the Uralides has an overall bivergent structural architecture, but with significantly different reflectivity characteristics from one tectonic zone to another. The integration of other types of data sets with the seismic data allows us to interpret what tectonic processes where responsible for the formation of the structural architecture, and when they were active. On the basis of these data, we suggest that the changes in the crustal-scale structural architecture indicate that there was significant partitioning of tectonothermal conditions and deformation from zone to zone across major fault systems, and between the lower and upper crust. Also, a number of the structural features revealed in the bivergent architecture of the orogen formed either in the Neoproterozoic or in the Paleozoic, prior to continent-continent collision. From the end of continent-continent collision to the present, low-temperature thermochronology suggests that the evolution of the Uralides has been dominated by erosion and slow exhumation. Despite some evidence for more recent topographic uplift, it has so far proven difficult to quantify it.

  3. Observational Evidence of Changes in Soil Temperatures across Eurasian Continent

    NASA Astrophysics Data System (ADS)

    Zhang, T.

    2015-12-01

    Soil temperature is one of the key climate change indicators and plays an important role in plant growth, agriculture, carbon cycle and ecosystems as a whole. In this study, variability and changes in ground surface and soil temperatures up to 3.20 m were investigated based on data and information obtained from hydrometeorological stations across Eurasian continent since the early 1950s. Ground surface and soil temperatures were measured daily by using the same standard method and by the trained professionals across Eurasian continent, which makes the dataset unique and comparable over a large study region. Using the daily soil temperature profiles, soil seasonal freeze depth was also obtained through linear interpolation. Preliminary results show that soil temperatures at various depths have increased dramatically, almost twice as much as air temperature increase over the same period. Regionally, soil temperature increase was more dramatically in high northern latitudes than mid/lower latitude regions. Air temperature changes alone may not be able to fully explain the magnitude of changes in soil temperatures. Further study indicates that snow cover establishment started later in autumn and snow cover disappearance occurred earlier in spring, while winter snow depth became thicker with a decreasing trend of snow density. Changes in snow cover conditions may play an important role in changes of soil temperatures over the Eurasian continent.

  4. Is "Warm Arctic, Cold Continent" A Fingerprint Pattern of Climate Change?

    NASA Astrophysics Data System (ADS)

    Hoerling, M. P.; Sun, L.; Perlwitz, J.

    2015-12-01

    Cold winters and cold waves have recently occurred in Europe, central Asia and the Midwest to eastern United States, even as global mean temperatures set record highs and Arctic amplification of surface warming continued. Since 1979, Central Asia winter temperatures have in fact declined. Conjecture has it that more cold extremes over the mid-latitude continents should occur due to global warming and the impacts of Arctic sea ice loss. A Northern Hemisphere temperature signal termed the "Warm Arctic, Cold Continent" pattern has thus been surmised. Here we use a multi-model approach to test the hypothesis that such a pattern is indeed symptomatic of climate change. Diagnosis of a large model ensemble of historical climate simulations shows some individual realizations to yield cooling trends over Central Asia, but importantly the vast majority show warming. The observed cooling has thus likely been a low probability state of internal variability, not a fingerprint of forced climate change. We show that daily temperature variations over continents decline in winter due to global warming, and cold waves become less likely. This is partly related to diminution of Arctic cold air reservoirs due to warming-induced sea ice loss. Nonetheless, we find some evidence and present a physical basis that Arctic sea ice loss alone can induce a winter cooling over Central Asia, though with a magnitude that is appreciably smaller than the overall radiative-forced warming signal. Our results support the argument that recent cooling trends over central Asia, and cold extreme events over the winter continents, have principally resulted from atmospheric internal variability and have been neither a forced response to Arctic seas ice loss nor a symptom of global warming. The paradigm of climate change is thus better expressed as "Warm Arctic, Warm Continent" for the NH winter.

  5. Landscape-scale Habitat Templates and Life Histories of Endangered and Invasive Fish Species in Large Rivers of the Mid-Continent USA (Invited)

    NASA Astrophysics Data System (ADS)

    Jacobson, R. B.; Braaten, P. J.; Chapman, D.; DeLonay, A. J.

    2013-12-01

    Many fish species migrate through river systems to complete their life cycles, occupying specific habitats during specific life stages. Regional geomorphology sets a template for their habitat-use patterns and ontogenetic development. In large rivers of the Mid-continent USA, understanding of relations of fish life histories to landscape-scale habitat templates informs recovery of endangered species and prevention of spread of invasive species. The endangered pallid sturgeon has evolved in the Missouri-Mississippi river system over 150 Ma. Its present-day distribution probably results from extensive drainage re-arrangements during the Pleistocene, followed by contemporary fragmentation. The reproductive and early life-stage needs of pallid sturgeon encompass hundreds of km, as adults migrate upstream to spawn and free embryos and larvae disperse downstream. Spawning requires coarse, hard substrate for incubation of adhesive eggs but adult pallid sturgeon are found predominately over sand, indicating that coarse substrate is a critical but transient habitat need. Once hatched, free-embryos initiate 9-17 days of downstream dispersal that distributes them over several hundreds of km. Lotic conditions at the dispersal terminus are required for survival. Persistent recruitment failure has been attributed to dams and channelization, which have fragmented migration and dispersal corridors, altered flow regimes, and diminished rearing habitats. Key elements of the natural history of this species remain poorly understood because adults are rare and difficult to observe, while the earliest life stages are nearly undetectable. Recent understanding has been accelerated using telemetry and hydroacoustics, but such assessments occur in altered systems and may not be indicative of natural behaviors. Restoration activities attempt - within considerable uncertainty -- to restore elements of the habitat template where they are needed. In comparison, invasive Asian carps have been

  6. Continents as lithological icebergs: The importance of buoyant lithospheric roots

    USGS Publications Warehouse

    Abbott, D.H.; Drury, R.; Mooney, W.D.

    1997-01-01

    An understanding of the formation of new continental crust provides an important guide to locating the oldest terrestrial rocks and minerals. We evaluated the crustal thicknesses of the thinnest stable continental crust and of an unsubductable oceanic plateau and used the resulting data to estimate the amount of mantle melting which produces permanent continental crust. The lithospheric mantle is sufficiently depleted to produce permanent buoyancy (i.e., the crust is unsubductable) at crustal thicknesses greater than 25-27 km. These unsubductable oceanic plateaus and hotspot island chains are important sources of new continental crust. The newest continental crust (e.g., the Ontong Java plateau) has a basaltic composition, not a granitic one. The observed structure and geochemistry of continents are the result of convergent margin magmatism and metamorphism which modify the nascent basaltic crust into a lowermost basaltic layer overlain by a more silicic upper crust. The definition of a continent should imply only that the lithosphere is unsubductable over ??? 0.25 Ga time periods. Therefore, the search for the oldest crustal rocks should include rocks from lower to mid-crustal levels.

  7. Exploring the source of the mid-level hump for intensity discrimination in quiet and the effects of noisea)

    PubMed Central

    Roverud, Elin; Strickland, Elizabeth A.

    2015-01-01

    Intensity discrimination Weber fractions (WFs) measured for short, high-frequency tones in quiet are larger at mid levels than at lower or higher levels. The source of this “mid-level hump” is a matter of debate. One theory is that the mid-level hump reflects basilar-membrane compression, and that WFs decrease at higher levels due to spread-of-excitation cues. To test this theory, Experiment 1 measured the mid-level hump and growth-of-masking functions to estimate the basilar membrane input/output (I/O) function in the same listeners. Results showed the initial rise in WFs could be accounted for by the change in I/O function slope, but there was additional unexplained variability in WFs. Previously, Plack [(1998). J. Acoust. Soc. Am. 103(5), 2530–2538] showed that long-duration notched noise (NN) presented with the tone reduced the mid-level hump even with a temporal gap in the NN. Plack concluded the results were consistent with central profile analysis. However, simultaneous, forward, and backward NN were not examined separately, which may independently test peripheral and central mechanisms of the NN. Experiment 2 measured WFs at the mid-level hump in the presence of NN and narrowband noise of different durations and temporal positions relative to the tone. Results varied across subjects, but were consistent with more peripheral mechanisms. PMID:25786945

  8. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) The search for another field site was abandoned after discussion with DOE. There is a clear absence of willing industry partners to participate in this project. The greatest obstacle is having the necessary data to perform

  9. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Type curve matching continued during the reporting period. (2) A second data collection trip to Tulsa was performed to gather information on the additional reservoirs to be included in the analysis. Created updated

  10. Continence and pelvic floor status in nulliparous women at midterm pregnancy.

    PubMed

    Hilde, Gunvor; Stær-Jensen, Jette; Ellström Engh, Marie; Brækken, Ingeborg Hoff; Bø, Kari

    2012-09-01

    A Cochrane review recommends antenatal pelvic floor muscle training (PFMT) in urinary incontinence (UI) prevention. The aim of the study was to investigate nulliparous pregnant women's knowledge about and practising of PFMT, their pelvic floor muscle (PFM) function, and ability to contract correctly. It was hypothesized that continent women had higher PFM strength and endurance than women with UI. Three hundred nulliparous women at gestational week 18-22 were included in a cross-sectional study. Vaginal resting pressure, maximum voluntary contraction, and PFM endurance were measured by manometer. UI was assessed by International Consultation on Incontinence Questionnaire Urinary Incontinence Short Form (ICIQ-UI-SF). Comparisons of PFM function in continent women and women with UI were analyzed using independent-samples t test. Mean differences with 95 % confidence interval (CI) are presented. Of 300 women, 89 % had heard of PFMT at mid pregnancy, and 35 % performed PFMT once or more a week. After thorough instruction 4 % were unable to contract correctly. Thirty-five percent reported UI, of whom 48 % performed PFMT once or more a week. Continent women had significantly higher PFM strength and endurance when compared with women having UI, with mean differences of 6.6 cmH(2)O (CI 2.3-10.8, p = 0.003), and 41.5 cmH(2)Osec (CI 9.8-73.1, p = 0.010), respectively. No difference was found for vaginal resting pressure (p = 0.054). Most nulliparous pregnant women knew about PFMT. Thirty-five percent performed PFMT once or more a week. Incontinent nulliparous pregnant women had weaker PFM than their continent counterparts. More emphasis on information regarding PFM function and PFMT is warranted during pregnancy.

  11. Evolving Continents

    NASA Astrophysics Data System (ADS)

    Hamilton, Warren

    Brian Windley succeeds very well indeed at the formidable task he sets for himself in this greatly revised second edition of a book that first appeared in 1977. He synthesizes primarily the tectonic and petrologic evolution of the continents and secondarily their economic geologic, stratigraphic, and biologic history. The book is organized in well-balanced time sequence and topical chapters, followed by a fine overview. The author describes examples, generalizes from them, and seeks understanding of variations with time and with depth of the process acting on continents within a plate tectonic framework.

  12. Correlation between continent area and elevation

    NASA Astrophysics Data System (ADS)

    Zhang, Y.

    2004-12-01

    This presentation is motivated by the following questions: (1) What factors determine the mean elevation and thickness of an individual continent? (2) How to explain the positive correlation between the mean height and area of individual continent? (3) Given total continental crust volume, what determines the mean thickness (and hence total area) of all continents? For example, Mean thickness of all continents is about 41 km. Mean land elevation is 874 m, and mean elevation of all continents (including land areas and continental shelves and slopes to 1000 meters below sea level) is about 800 m. Could mean continental thickness have doubled and continental area have halved in the geologic past? I present a first-order model to address these issues assuming that continental mean height is the steady state height controlled by uplift and erosion. The model predicts that it takes longer time to erode a larger continent. Hence mean continental height at steady state increases as continental area increases. This prediction is consistent with the general trend between present-day continental elevation and area (except for Antarctica), and can fit the trend well. This is the first time the relation between continental area and mean elevation is quantitatively explained. The model is further applied to investigate variations of mean thickness of continental crust over the last 600 Myr over which the continental crust mass and seawater volume are assumed to be constant. Because a change in the number of continents leads to change in the area of continents, it is predicted that the mean continental thickness increases as the number of continents decreases. Nevertheless, the thickness variation is small, amounts to about 10% from one continent to six continents. Change in the number of continents leads to a sea level fluctuation of about 0.3 km, with the lowest sea level coinciding with times of supercontinents. This prediction is consistent with prominent lows in sea level

  13. Mid-Holocene climates of the Americas: A dynamical response to changed seasonality

    USGS Publications Warehouse

    Harrison, S.P.; Kutzbach, J.-E.; Liu, Z.; Bartlein, P.J.; Otto-Bliesner, B.; Muhs, D.; Prentice, I.C.; Thompson, R.S.

    2003-01-01

    Simulations of the climatic response to mid-Holocene (6 ka BP) orbital forcing with two coupled ocean-atmosphere models (FOAM and CSM) show enhancement of monsoonal precipitation in parts of the American Southwest, Central America and northern-most South America during Northern Hemisphere summer. The enhanced onshore flow that brings precipitation into Central America is caused by a northward displacement of the inter-tropical convergence zone, driven by cooling of the equatorial and warming of the northern subtropical and mid-latitude ocean. Ocean feedbacks also enhance precipitation over the American Southwest, although the increase in monsoon precipitation there is largely driven by increases in land-surface temperature. The northward shift in the equatorial precipitation band that causes enhanced precipitation in Central America and the American Southwest has a negative feedback effect on monsoonal precipitation in northern South America. The simulations demonstrate that mid-Holocene aridity in the mid-continent of North America is dynamically linked to the orbitally induced enhancement of the summer monsoon in the American Southwest, with a spatial structure (wet in the Southwest and dry in the mid-continent) similar to that found in strong monsoon years today. Changes in winter precipitation along the west coast of North America, in Central America and along the Gulf Coast, caused by southward-displacement of the westerly storm tracks, indicate that changes in the Northern Hemisphere winter monsoon also play a role in regional climate changes during the mid-Holocene. Although the simulations with FOAM and CSM differ in detail, the general mechanisms and patterns are common to both. The model results thus provide a coherent dynamical explanation for regional patterns of increased or decreased aridity shown by vegetation, lake status and aeolian data from the Americas.

  14. Continent cutaneous diversion.

    PubMed

    Skinner, Eila C

    2015-11-01

    This article updates the recently reported intermediate to long-term results with the most commonly used forms of continent cutaneous urinary diversion, and to discuss approaches to early and late complications. Many variations on construction of a continent cutaneous diversion have been described. Results with large series of patients demonstrate acceptable results with all of them, but with a significant revision rate. Long-term complication rates and adaptation to robotic approaches have recently been described. Continent cutaneous diversion is rarely offered in the USA to patients undergoing cystectomy except in a few centers. Most studies have found a high complication rate and need for revision surgery in 10-20% of patients. However, functional results are acceptable and many patients are willing to accept the complications in exchange for avoiding an external appliance.

  15. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-03-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin ofmore » economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Continued to solicit industry research partners to provide test sites, including Patina Oil and Gas and EOG Resources, each of whom have previously worked with ARI on a similar projects funded by the Gas Technology

  16. SELECTION AND TREATMENT OF STRIPPER GAS WELLS FOR PRODUCTION ENHANCEMENT IN THE MID-CONTINENT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Scott Reeves

    2003-08-01

    Stripper gas wells are an important source of domestic energy supply and under constant threat of permanent loss (shut-in) due to marginal economics. In 1998, 192 thousand stripper gas wells produced over a Tcf of gas, at an average rate of less than 16 Mcfd. This represents about 57% of all producing gas wells in the onshore lower-48 states, yet only 8% of production. Reserves of stripper gas wells are estimated to be only 1.6 Tcf, or slightly over 1% of the onshore lower-48 total (end of year 1996 data). Obviously, stripper gas wells are at the very margin of economic sustenance. As the demand for natural gas in the U.S. grows to the forecasted estimate of over 30 Tcf annually by the year 2010, supply from current conventional sources is expected to decline. Therefore, an important need exists to fully exploit known domestic resources of natural gas, including those represented by stripper gas wells. The overall objectives of this project are to develop an efficient and low-cost methodology to broadly categorize the well performance characteristics for a stripper gas field, identify the high-potential candidate wells for remediation, and diagnose the specific causes for well underperformance. With this capability, stripper gas well operators can more efficiently and economically produce these resources and maximize these gas reserves. A further objective is to identify/develop, evaluate and test ''new and novel,'' economically viable remediation options. Finally, it is the objective of this project that all the methods and technologies developed in this project, while being tested in the Mid-Continent, be widely applicable to stripper gas wells of all types across the country. The project activities during the reporting period were: (1) Compiled information and results of field activities that Oneok has conducted in relation to the project. Field activities have included performing six pressure transient tests, and implementing six workovers, four of which were

  17. The provenance and chemical variation of sandstones associated with the Mid-continent Rift System, U.S.A.

    USGS Publications Warehouse

    Cullers, R.L.; Berendsen, P.

    1998-01-01

    Sandstones along the northern portion of the Precambrian Mid-continent Rift System (MRS) have been petrographically and chemically analyzed for major elements and a variety of trace elements, including the REE. After the initial extrusion of the abundant basalts along the MRS, dominantly volcaniclastic sandstones of the Oronto Group were deposited. These volcaniclastic sandstones are covered by quartzose and subarkosic sandstones of the Bayfield Group. Thus the sandstones of the Oronto Group were derived from previously extruded basalts, whereas, the sandstones of the Bayfield Group were derived from Precambrian granitic gneisses located on the rift flanks. The chemical variation of these sandstones closely reflects the changing detrital modes with time. The elemental composition of the sandstones confirms the source lithologies suggested by the mineralogy and clasts. The Oronto Group sandstones contain lower ratios of elements concentrated in silicic source rocks (La or Th) relative to elements concentrated in basic source rocks (Co, Cr, or Sc) than the Bayfield Group. Also, the average size of the negative Eu anomaly of the sandstones of the Oronto Group is significantly less (Eu/Eu* mean ?? standard deviation = 0.79 ?? 0.13) than that of the Bayfield Group (mean + standard deviation = 0.57 ?? 0.09), also suggesting a more basic source for the former than the latter. Mixing models of elemental ratios give added insight as to the evolution of the rift. These models suggest that the volcanistic sandstones of the lower portion of the Oronto Group are derived from about 80 to 90 percent basalt and 10 to 20 percent granitoids. The rest of the Oronto Group and the lower to middle portion of the Bayfield Group could have formed by mixing of about 30 to 60 percent basalt and 40 to 70 percent granitoids. The upper portion of the Bayfield Group is likely derived from 80 to 100 percent granitoids and zero to 20 percent basalt.

  18. Comparison of Historically Severe Droughts and the Vulnerability of Agroecosystems in Mid-Continent USA: Lessons Learned

    NASA Astrophysics Data System (ADS)

    Olson, C.; Rippey, B.

    2016-12-01

    Extreme climatic events, drought, flooding, severe storms, tropical cyclones and winter storms have cost the USA billions of dollars. Although among major natural disasters in the last 100 years, severe drought occurrences are lower in terms of discrete events than that for other extreme events, the average cost per drought event exceeds all but those of severe storms and tropical cyclones and has significantly impacted the US agroecosystems upon which much of the domestic and export food markets depend1. The impacts from the 2012, 1988, and 1950's droughts are compared with the effects on cropland in the Mid-Continent US. Drought severity in 2012 and in 1988 were similar in terms of economic agricultural loss, 40 and 31 billion in cost-adjusted dollars, respectively. The 2012 drought covered a geographic areal extent similar to that of an earlier drought in the 1950's; roughly 2/3 of the central USA was impacted. However, the 2012 drought developed relatively rapidly in less than a year whereas the drought of the 1950's was marked by multiple years of extreme heat and lack of precipitation. Each of these severe droughts has resulted in significant losses, but the 2012 drought, while costly, could have been a larger economic disaster had the same conditions occurred in the 1950's or 1988. Investment in new technology, improvements in irrigation efficiency and advanced drainage systems, targeted soil conservation practices, and flexibility to adapt to conditions have improved the resilience of agroecosystems to drought in the intervening years. Droughts continue to occur, so a better understanding of climate and available climate services along with sustained investment in new technology will improve drought tolerance. The recent establishment of USDA Regional Climate Hubs to translate and deliver science-based, region-specific information for individual natural resource managers will enable climate-smart decision-making. Implementation is now possible at scales

  19. [Continent ileostomy--indication and possibilities].

    PubMed

    Hahnloser, P; Säuberli, H; Geroulanos, S; Schauwecker, H H; Kock, N G

    1975-06-21

    Proctocolectomy with conventional ileostomy cures patients with severe ulcerative colitis but ileostomy appliances must be worn for the rest of their lives. The continent ileostomy, as devised by Kock, provides the patient with an intraabdominal ileal reservoir and a valve constructed by invaginating the efferent ileal segment into the reservoir. The patient empties his reservoir 2-3 times a day by inserting a catheter through the valve. Our experience with 14 patients is reported. The continent ileostomy was in most cases constructed as a second procedure after proctocolectomy. Minor postoperative complications, such as abscess, fistula or partial luxation of the valve were easily corrected. One patient who underwent proctocolectomy and simultaneous construction of a continent ileostomy died in acute liver failure due to a severe preexisting cirrhosis. All the other patients are continent for feces and gas and do not need external appliances. The construction of a continent ileostomy as a secondary procedure can be recommended in patients with proctocolectomy. It offers patients a life situation with differs only insignificantly from that of normal persons.

  20. Early onset of industrial-era warming across the oceans and continents.

    PubMed

    Abram, Nerilie J; McGregor, Helen V; Tierney, Jessica E; Evans, Michael N; McKay, Nicholas P; Kaufman, Darrell S

    2016-08-25

    The evolution of industrial-era warming across the continents and oceans provides a context for future climate change and is important for determining climate sensitivity and the processes that control regional warming. Here we use post-ad 1500 palaeoclimate records to show that sustained industrial-era warming of the tropical oceans first developed during the mid-nineteenth century and was nearly synchronous with Northern Hemisphere continental warming. The early onset of sustained, significant warming in palaeoclimate records and model simulations suggests that greenhouse forcing of industrial-era warming commenced as early as the mid-nineteenth century and included an enhanced equatorial ocean response mechanism. The development of Southern Hemisphere warming is delayed in reconstructions, but this apparent delay is not reproduced in climate simulations. Our findings imply that instrumental records are too short to comprehensively assess anthropogenic climate change and that, in some regions, about 180 years of industrial-era warming has already caused surface temperatures to emerge above pre-industrial values, even when taking natural variability into account.

  1. Continence following radical retropubic prostatectomy using self-reporting instruments.

    PubMed

    Lepor, Herbert; Kaci, Ledia; Xue, Xiaonan

    2004-03-01

    We performed a global self-assessment of continence following radical retropubic prostatectomy (RRP) and determined how this global self-assessment of continence correlates with commonly used definitions of continence. Between October 2000 and February 2002 all men who underwent RRP were encouraged to complete the University of California-Los Angeles Prostate Cancer Index 3, 6, 12 and 24 months postoperatively. Beginning October 2002 a single question capturing the patient global self-assessment of continence status was added to the postoperative continence assessment. The study design was cross-sectional since only continence surveys submitted between October 2002 through February 2003 were evaluated. Sensitivity, specificity and kappa coefficient was determined for the relationship between the patient global assessment of continence vs the definition of continence based on pad requirement, problem due to incontinence and frequency of incontinence. Continence progressively improved 3 to 24 months following RRP for all continence outcomes. At 24 months following RRP 97.1% of men considered themselves continent, while 97.1%, 94.1% and 97.1% were considered continent using continence definitions, including the requirement of no or 1 pad in a 24-hour interval, no or slight bother due to incontinence and total control or occasional dribbling, respectively. Our 3 definitions of continence derived from responses to the University of California-Los Angeles Prostate Cancer Index had excellent agreement with patient global self-assessment of continence (kappa coefficients between 0.76 and 0.83). The majority of men achieve continence without invasive intervention following RRP. Final continence status should be ascertained at 24 months. The patient global assessment of continence provides face validity for other definitions of continence based on responses to validated self-administered questionnaires.

  2. Ophiolites in ocean-continent transitions: From the Steinmann Trinity to sea-floor spreading

    NASA Astrophysics Data System (ADS)

    Bernoulli, Daniel; Jenkyns, Hugh C.

    2009-05-01

    Before the theory of plate tectonics took hold, there was no coherent model for ocean-continent transitions that included both extant continental margins and fragmentary ancient examples preserved in orogenic belts. Indeed, during the early 1900, two strands of thought developed, one relying on the antiquity and permanence of continents and oceans, advocated by the mainstream of the scientific community and one following mobilist concepts derived from Wegener's hypothesis (1915) of continental drift. As an illustration of the prevailing North-American view, the different composition and thickness of continental and oceanic crust and the resulting isostatic response showed "how improbable it would be to suppose that a continent could founder or go to oceanic depth or that ocean floor at ± 3000 fathoms could ever have been a stable land area since the birth of the oceans" [H.H. Hess, Trans. R. Soc. London, A 222 (1954) 341-348]. Because of the perceived permanence of oceans and continents, mountain chains were thought to originate from narrow, elongated, unstable belts, the geosynclines, circling the continents or following "zones of crustal weakness" within them, from which geanticlines and finally mountain belts would develop. This teleological concept, whereby a geosyncline would inevitably evolve into a mountain chain, dominated geological interpretations of orogenic belts for several decades in the mid-twentieth century. However, the concept of permanence of oceans and continents and the concept of the geosyncline had already met with the critiques of Suess and others. As early as 1905, Steinmann considered the association of peridotite, "diabase" (basalt/dolerite) and radiolarite (a typical ocean-continent transition assemblage), present in the Alps and Apennines, as characteristic of the deep-ocean floor and Bailey (1936) placed Steinmann's interpretation into the context of continental drift and orogeny. Indeed, in both authors' writings, the concept of

  3. Seismic imaging of a mid-lithospheric discontinuity beneath Ontong Java Plateau

    NASA Astrophysics Data System (ADS)

    Tharimena, Saikiran; Rychert, Catherine A.; Harmon, Nicholas

    2016-09-01

    Ontong Java Plateau (OJP) is a huge, completely submerged volcanic edifice that is hypothesized to have formed during large plume melting events ∼90 and 120 My ago. It is currently resisting subduction into the North Solomon trench. The size and buoyancy of the plateau along with its history of plume melting and current interaction with a subduction zone are all similar to the characteristics and hypothesized mechanisms of continent formation. However, the plateau is remote, and enigmatic, and its proto-continent potential is debated. We use SS precursors to image seismic discontinuity structure beneath Ontong Java Plateau. We image a velocity increase with depth at 28 ± 4 km consistent with the Moho. In addition, we image velocity decreases at 80 ± 5 km and 282 ± 7 km depth. Discontinuities at 60-100 km depth are frequently observed both beneath the oceans and the continents. However, the discontinuity at 282 km is anomalous in comparison to surrounding oceanic regions; in the context of previous results it may suggest a thick viscous root beneath OJP. If such a root exists, then the discontinuity at 80 km bears some similarity to the mid-lithospheric discontinuities (MLDs) observed beneath continents. One possibility is that plume melting events, similar to that which formed OJP, may cause discontinuities in the MLD depth range. Plume-plate interaction could be a mechanism for MLD formation in some continents in the Archean prior to the onset of subduction.

  4. Continent cecostomy. An account of 30 patients.

    PubMed

    Kock, N G; Myrvold, H E; Philipson, B M; Svaninger, G; Ojerskog, B

    1985-10-01

    In this paper, an account is given of our experience with continent colostomy in man. In five patients, the end-sigmoidostomy was provided with an intussusception valve. Evacuation of the bowel by irrigation through a catheter was laborious and time-consuming and this method was abandoned. In another group of 30 patients, the cecum was isolated from the rest of the colon and its distal end was provided with an intussusception valve. Of the 30 patients, eight were later given continent ileostomies, two were converted to conventional sigmoidostomies, and one patient with fecal incontinence preferred to have intestinal continuity reestablished. Thus, 19 patients still have continent cecostomies and are satisfied with their function. When comparing the function of the continent cecostomy with that of the continent ileostomy, however, it is obvious that the ileostomy function is superior. The experience obtained with this group of patients has resulted in a widening of the indications for constructing a continent ileostomy, including selected patients with various anorectal disorders.

  5. Application of a geographic information system in analyzing the occurrence of atrazine in groundwater of the mid-continental United States

    USGS Publications Warehouse

    Burkart, M.R.; Kolpin, D.W.

    1993-01-01

    The US Geological Survey, US Department of Agriculture, and US Environmental Protection Agency are conducting research and regional assessments in support of policy alternatives intended to protect water resources from agricultural chemical contamination. The mid-continent was selected because of the intense row crop agriculture and associated herbicide application in this region. An application of a geographic information system is demonstrated for analyzing and comparing the distribution of estimated atrazine use to the detection rate of atrazine in groundwater. Understanding the relations between atrazine use and detection in groundwater is important in policy deliberations to protect water resources. Relational analyses between measures of chemical use and detection rate by natural resource units may provide insight into critical factors controlling the processes that result in groundwater contamination from agricultural chemicals. 

  6. [The Kock continent urinary diversion].

    PubMed

    Boyd, S D; Skinner, D G; Lieskovsky, G

    1989-07-01

    The continent ileal reservoir as conceived by Kock produces a low-pressure, high-capacity reservoir with continent and nonrefluxing valves constructed from ileum. From August 1982 through March 1988, 531 patients underwent continent urinary diversion via a Kock reservoir at our institution. Of these, 39 males had a Kock bladder substitution, while the rest underwent cutaneous Kock diversion. Early complications occurred in 16% of all patients, and there was an operative mortality rate of 1.9%. Surgical modifications of nipple fixation, which are discussed in detail in this paper, help to reduce late complications to less than 10%. Patient satisfaction with both procedures remains excellent.

  7. The Influence of a Substellar Continent on the Climate of a Tidally Locked Exoplanet

    NASA Astrophysics Data System (ADS)

    Lewis, Neil T.; Lambert, F. Hugo; Boutle, Ian A.; Mayne, Nathan J.; Manners, James; Acreman, David M.

    2018-02-01

    Previous studies have demonstrated that continental carbon-silicate weathering is important to the continued habitability of a terrestrial planet. Despite this, few studies have considered the influence of land on the climate of a tidally locked planet. In this work we use the Met Office Unified Model, coupled to a land-surface model, to investigate the climate effects of a continent located at the substellar point. We choose to use the orbital and planetary parameters of Proxima Centauri B as a template, to allow comparison with the work of others. A region of the surface where T s > 273.15 K is always retained, and previous conclusions on the habitability of Proxima Centauri B remain intact. We find that substellar land causes global cooling and increases day–night temperature contrasts by limiting heat redistribution. Furthermore, we find that substellar land is able to introduce a regime change in the atmospheric circulation. Specifically, when a continent offset to the east of the substellar point is introduced, we observe the formation of two mid-latitude counterrotating jets, and a substantially weakened equatorial superrotating jet.

  8. Rapid measurement of human milk macronutrients in the neonatal intensive care unit: accuracy and precision of fourier transform mid-infrared spectroscopy.

    PubMed

    Smilowitz, Jennifer T; Gho, Deborah S; Mirmiran, Majid; German, J Bruce; Underwood, Mark A

    2014-05-01

    Although it is well established that human milk varies widely in macronutrient content, it remains common for human milk fortification for premature infants to be based on historic mean values. As a result, those caring for premature infants often underestimate protein intake. Rapid precise measurement of human milk protein, fat, and lactose to allow individualized fortification has been proposed for decades but remains elusive due to technical challenges. This study aimed to evaluate the accuracy and precision of a Fourier transform (FT) mid-infrared (IR) spectroscope in the neonatal intensive care unit to measure human milk fat, total protein, lactose, and calculated energy compared with standard chemical analyses. One hundred sixteen breast milk samples across lactation stages from women who delivered at term (n = 69) and preterm (n = 5) were analyzed with the FT mid-IR spectroscope and with standard chemical methods. Ten of the samples were tested in replicate using the FT mid-IR spectroscope to determine repeatability. The agreement between the FT mid-IR spectroscope analysis and reference methods was high for protein and fat and moderate for lactose and energy. The intra-assay coefficients of variation for all outcomes were less than 3%. The FT mid-IR spectroscope demonstrated high accuracy in measurement of total protein and fat of preterm and term milk with high precision.

  9. Analysis of continence rates following robot-assisted radical prostatectomy: strict leak-free and pad-free continence.

    PubMed

    Reynolds, W Stuart; Shikanov, Sergey A; Katz, Mark H; Zagaja, Gregory P; Shalhav, Arieh L; Zorn, Kevin C

    2010-02-01

    To propose a strict and specific definition of continence (leak-free and pad-free [LFPF]) and apply it to robot-assisted radical prostatectomy (RARP) outcomes on the basis of University of California-Los Angeles-Prostate Cancer Index (UCLA-PCI), as postprostatectomy incontinence is not well defined. A single-institution RARP database was reviewed concerning continence variables prospectively recorded by the UCLA-PCI. Specific responses to urinary function and continence items were reviewed at baseline and 1, 3, 6, 12, and 24 months after surgery. From February 2003 to September 2007, a total of 1005 of 1500 RARP patients had data available for review. At baseline, only 73% of these patients were LFPF. This decreased to 4%, 9%, 17%, 24%, and 28% at 1, 3, 6, 12, and 24 months after surgery, respectively. Applying less strict definitions, at 24 months, 68% of patients reported no pad use and 90% of patients reported no pad use or the use of a security pad. When stratified by baseline LFPF status, patients not LFPF at baseline had higher baseline international prostate symptom score scores, lower urinary function scores, lower urinary bother scores, and larger prostate weights. Patients LFPF at baseline disproportionately regained LFPF continence starting 6 months after surgery compared with those not LFPF at baseline: 20% vs 9% (P = .005), 27% vs 15% (P = .0009), and 33% vs 15% (P = .0146) at 6, 12, and 24 months, respectively. A strict definition of urinary continence results in more conservative postoperative outcomes. Preoperative LFPF status can be predictive of postoperative LFPF continence. However, only one-third of patients LFPF at baseline returned to LFPF at 24 months. 2010 Elsevier Inc. All rights reserved.

  10. Dissociation of β-Sheet Stacking of Amyloid β Fibrils by Irradiation of Intense, Short-Pulsed Mid-infrared Laser.

    PubMed

    Kawasaki, Takayasu; Yaji, Toyonari; Ohta, Toshiaki; Tsukiyama, Koichi; Nakamura, Kazuhiro

    2018-02-05

    Structure of amyloid β (Aβ) fibrils is rigidly stacked by β-sheet conformation, and the fibril state of Aβ is profoundly related to pathogenesis of Alzheimer's disease (AD). Although mid-infrared light has been used for various biological researches, it has not yet been known whether the infrared light changes the fibril structure of Aβ. In this study, we tested the effect of irradiation of intense mid-infrared light from a free-electron laser (FEL) targeting the amide bond on the reduction of β-sheet content in Aβ fibrils. The FEL reduced entire contents of proteins exhibiting β-sheet structure in brain sections from AD model mice, as shown by synchrotron-radiation infrared microscopy analysis. Since Aβ 1-42 fibril absorbed a considerable FEL energy at amide I band (6.17 μm), we irradiated the FEL at 6.17 μm and found that β-sheet content of naked Aβ 1-42 fibril was decreased using infrared microscopic analysis. Consistent with the decrease in the β-sheet content, Congo-red signal is decreased after the irradiation to Aβ 1-42 fibril. Furthermore, electron microscopy analysis revealed that morphologies of the fibril and proto-fibril were largely changed after the irradiation. Thus, mid-infrared light dissociates β-sheet structure of Aβ fibrils, which justifies exploration of possible laser-based therapy for AD.

  11. Tape functionality: position, change in shape, and outcome after TVT procedure--mid-term results.

    PubMed

    Kociszewski, Jacek; Rautenberg, Oliver; Kolben, Sebastian; Eberhard, Jakob; Hilgers, Reinhard; Viereck, Volker

    2010-07-01

    This study evaluates the relevance of the tape position and change in shape (tape functionality) under in vivo conditions for mid-term outcome. Changes in the sonographic tension-free vaginal tape (TVT) position relative to the percentage urethral length and the tape-urethra distance were determined after 6 and 48 months in 41 women with stress urinary incontinence. At 48 months, 76% (31/41) of women were cured, 17% (7/41) were improved, and 7% (3/41) were failures. Disturbed bladder voiding was present in 12% (5/41), de novo urge incontinence in 7% (3/41). The median TVT position was at 63% of urethral length. Median tape-urethra distance was 2.7 mm, ranging from 2.9 mm in continent patients without complications to 1.1 mm in those with obstructive complications. Patients with postoperative urine loss had a median distance of 3.9 mm. The tape was stretched at rest and C-shaped during straining in 15 of 41 women (37%) at 48 months (all continent). Patients with this tape functionality at 6 months were also cured at 48 months in 86% of cases (19/22), and only 14% (3/22) showed recurrent incontinence. Mid-term data suggest an optimal outcome if the tape is positioned at least 2 mm from the urethra at the junction of the middle and distal thirds. Patients with optimal tape functionality at 6 months are likely to show mid-term therapeutic success.

  12. 21 CFR 876.5320 - Nonimplanted electrical continence device.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nonimplanted electrical continence device. 876... Nonimplanted electrical continence device. (a) Identification. A nonimplanted electrical continence device is a device that consists of a pair of electrodes on a plug or a pessary that are connected by an electrical...

  13. 21 CFR 876.5320 - Nonimplanted electrical continence device.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Nonimplanted electrical continence device. 876... Nonimplanted electrical continence device. (a) Identification. A nonimplanted electrical continence device is a device that consists of a pair of electrodes on a plug or a pessary that are connected by an electrical...

  14. 21 CFR 876.5320 - Nonimplanted electrical continence device.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Nonimplanted electrical continence device. 876... Nonimplanted electrical continence device. (a) Identification. A nonimplanted electrical continence device is a device that consists of a pair of electrodes on a plug or a pessary that are connected by an electrical...

  15. 21 CFR 876.5320 - Nonimplanted electrical continence device.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Nonimplanted electrical continence device. 876... Nonimplanted electrical continence device. (a) Identification. A nonimplanted electrical continence device is a device that consists of a pair of electrodes on a plug or a pessary that are connected by an electrical...

  16. Surface temperatures of the Mid-Pliocene North Atlantic Ocean: Implications for future climate

    USGS Publications Warehouse

    Dowsett, Harry J.; Chandler, Mark A.; Robinson, Marci M.

    2009-01-01

    The Mid-Pliocene is the most recent interval in the Earth's history to have experienced warming of the magnitude predicted for the second half of the twenty-first century and is, therefore, a possible analogue for future climate conditions. With continents basically in their current positions and atmospheric CO2 similar to early twenty-first century values, the cause of Mid-Pliocene warmth remains elusive. Understanding the behaviour of the North Atlantic Ocean during the Mid-Pliocene is integral to evaluating future climate scenarios owing to its role in deep water formation and its sensitivity to climate change. Under the framework of the Pliocene Research, Interpretation and Synoptic Mapping (PRISM) sea surface reconstruction, we synthesize Mid-Pliocene North Atlantic studies by PRISM members and others, describing each region of the North Atlantic in terms of palaeoceanography. We then relate Mid-Pliocene sea surface conditions to expectations of future warming. The results of the data and climate model comparisons suggest that the North Atlantic is more sensitive to climate change than is suggested by climate model simulations, raising the concern that estimates of future climate change are conservative.

  17. Exploring Research Contributions of the North American Carbon Program using Google Earth and Google Map

    NASA Astrophysics Data System (ADS)

    Griffith, P. C.; Wilcox, L. E.; Morrell, A.

    2009-12-01

    The central objective of the North American Carbon Program (NACP), a core element of the US Global Change Research Program, is to quantify the sources and sinks of carbon dioxide, carbon monoxide, and methane in North America and adjacent ocean regions. The NACP consists of a wide range of investigators at universities and federal research centers. Although many of these investigators have worked together in the past, many have had few prior interactions and may not know of similar work within knowledge domains, much less across the diversity of environments and scientific approaches in the Program. Coordinating interactions and sharing data are major challenges in conducting NACP. The Google Earth and Google Map Collections on the NACP website (www.nacarbon.org) provide a geographical view of the research products contributed by each core and affiliated NACP project. Other relevant data sources (e.g. AERONET, LVIS) can also be browsed in spatial context with NACP contributions. Each contribution links to project-oriented metadata, or “project profiles”, that provide a greater understanding of the scientific and social context of each dataset and are an important means of communicating within the NACP and to the larger carbon cycle science community. Project profiles store information such as a project's title, leaders, participants, an abstract, keywords, funding agencies, associated intensive campaigns, expected data products, data needs, publications, and URLs to associated data centers, datasets, and metadata. Data products are research contributions that include biometric inventories, flux tower estimates, remote sensing land cover products, tools, services, and model inputs / outputs. Project leaders have been asked to identify these contributions to the site level whenever possible, either through simple latitude/longitude pair, or by uploading a KML, KMZ, or shape file. Project leaders may select custom icons to graphically categorize their

  18. The pursuit of colostomy continence.

    PubMed

    Roberts, D J

    1997-03-01

    The lifelong management required by patients with permanent colostomies leads to dissatisfaction with quality of life for many. Through the years, multiple techniques have been attempted to improve the quality of life by pursuing colostomy continence. Such endeavors include surgical interventions, nonsurgical devices and management, and behavior modification techniques. Efforts in research and development continue, and the desire to achieve continence of the stoma remain common cause among persons with on ostomy and those involved in their care.

  19. NACP Synthesis: Evaluating modeled carbon state and flux variables against multiple observational constraints (Invited)

    NASA Astrophysics Data System (ADS)

    Thornton, P. E.; Nacp Site Synthesis Participants

    2010-12-01

    The North American Carbon Program (NACP) synthesis effort includes an extensive intercomparison of modeled and observed ecosystem states and fluxes preformed with multiple models across multiple sites. The participating models span a range of complexity and intended application, while the participating sites cover a broad range of natural and managed ecosystems in North America, from the subtropics to arctic tundra, and coastal to interior climates. A unique characteristic of this collaborative effort is that multiple independent observations are available at all sites: fluxes are measured with the eddy covariance technique, and standard biometric and field sampling methods provide estimates of standing stock and annual production in multiple categories. In addition, multiple modeling approaches are employed to make predictions at each site, varying, for example, in the use of diagnostic vs. prognostic leaf area index. Given multiple independent observational constraints and multiple classes of model, we evaluate the internal consistency of observations at each site, and use this information to extend previously derived estimates of uncertainty in the flux observations. Model results are then compared with all available observations and models are ranked according to their consistency with each type of observation (high frequency flux measurement, carbon stock, annual production). We demonstrate a range of internal consistency across the sites, and show that some models which perform well against one observational metric perform poorly against others. We use this analysis to construct a hypothesis for combining eddy covariance, biometrics, and other standard physiological and ecological measurements which, as data collection proceeded over several years, would present an increasingly challenging target for next generation models.

  20. Plasmodium vivax Diversity and Population Structure across Four Continents.

    PubMed

    Koepfli, Cristian; Rodrigues, Priscila T; Antao, Tiago; Orjuela-Sánchez, Pamela; Van den Eede, Peter; Gamboa, Dionicia; van Hong, Nguyen; Bendezu, Jorge; Erhart, Annette; Barnadas, Céline; Ratsimbasoa, Arsène; Menard, Didier; Severini, Carlo; Menegon, Michela; Nour, Bakri Y M; Karunaweera, Nadira; Mueller, Ivo; Ferreira, Marcelo U; Felger, Ingrid

    2015-01-01

    Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity, genotyping data from 11 microsatellite markers was either generated or compiled from 841 isolates from four continents collected in 1999-2008. Diversity was highest in South-East Asia (mean allelic richness 10.0-12.8), intermediate in the South Pacific (8.1-9.9) Madagascar and Sudan (7.9-8.4), and lowest in South America and Central Asia (5.5-7.2). A reduced panel of only 3 markers was sufficient to identify approx. 90% of all haplotypes in South Pacific, African and SE-Asian populations, but only 60-80% in Latin American populations, suggesting that typing of 2-6 markers, depending on the level of endemicity, is sufficient for epidemiological studies. Clustering analysis showed distinct clusters in Peru and Brazil, but little sub-structuring was observed within Africa, SE-Asia or the South Pacific. Isolates from Uzbekistan were exceptional, as a near-clonal parasite population was observed that was clearly separated from all other populations (FST>0.2). Outside Central Asia FST values were highest (0.11-0.16) between South American and all other populations, and lowest (0.04-0.07) between populations from South-East Asia and the South Pacific. These comparisons between P. vivax populations from four continents indicated that not only transmission intensity, but also geographical isolation affect diversity and population structure. However, the high effective population size results in slow changes of these parameters. This persistency must be taken into account when assessing the impact of control programs on the genetic structure of parasite populations.

  1. 75 FR 39680 - Houston Pipe Line Company LP, Worsham-Steed Gas Storage, L.P., Energy Transfer Fuel, LP, Mid...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-12

    ... Company LP, Worsham-Steed Gas Storage, L.P., Energy Transfer Fuel, LP, Mid Continent Market Center, L.L.C... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. PR10-44-000; Docket No. PR10... the protest or intervention to the Federal Energy Regulatory Commission, 888 First Street, NE...

  2. [Pseudo-continent perineal colostomy. Results and techniques].

    PubMed

    Lasser, P; Dubé, P; Guillot, J M; Elias, D

    1997-09-01

    This prospective study was conducted to assess functional results obtained after pseudo-continent perineal colostomy using the Schmidt procedure. Functional outcome was assessed in 40 patients who had undergone amputation of the rectum for cancer and pseudo-continent perineal colostomy reconstruction between 1989 and 1995 in our institution. The cancer pathology, operative procedure and post-operative care were noted. Morbidity, functional outcome and degree of patient satisfaction were recorded. Mean follow-up was 45 months (18-87) in 100% of the patients. There were no operative deaths. Twenty patients had post-operative complications and 2 patients required early conversion to definitive abdominal colostomy due to severe perineal complications. Function outcome showed normal continence in 4 patients, air incontinence in 23, occasional minimal leakage in 9 and incontinence requiring iliac colostomy in 2. Eighty-six percent of the patients were highly satisfied or satisfied with their continence capacity. Pseudo-continent perineal colostomy is a reliable technique which can be proposed as an alternative to left iliac colostomy after amputation of the rectum for cancer if a rigorous procedure is applied: careful patient selection, informed consent, rigorous surgical procedure, daily life-long irrigation of the colon.

  3. Emergence of silicic continents as the lower crust peels off on a hot plate-tectonic Earth

    NASA Astrophysics Data System (ADS)

    Chowdhury, Priyadarshi; Gerya, Taras; Chakraborty, Sumit

    2017-09-01

    The rock record and geochemical evidence indicate that continental recycling has been occurring since the early history of the Earth. The stabilization of felsic continents in place of Earth's early mafic crust about 3.0 to 2.0 billion years ago, perhaps due to the initiation of plate tectonics, implies widespread destruction of mafic crust during this time interval. However, the physical mechanisms of such intense recycling on a hotter, (late) Archaean and presumably plate-tectonic Earth remain largely unknown. Here we use thermomechanical modelling to show that extensive recycling via lower crustal peeling-off (delamination but not eclogitic dripping) during continent-continent convergence was near ubiquitous during the late Archaean to early Proterozoic. We propose that such destruction of the early mafic crust, together with felsic magmatism, may have caused both the emergence of silicic continents and their subsequent isostatic rise, possibly above the sea level. Such changes in the continental character have been proposed to influence the Great Oxidation Event and, therefore, peeling-off plate tectonics could be the geodynamic trigger for this event. A transition to the slab break-off controlled syn-orogenic recycling occurred as the Earth aged and cooled, leading to reduced recycling and enhanced preservation of the continental crust of present-day composition.

  4. [The continent ileostomy--indication and results].

    PubMed

    Säuberli, H; Akovbiantz, A; Hahnloser, P

    1982-01-01

    Proctocolectomy with conventional ileostomy cures patients with severe ulcerative colitis, however ileostomy appliances had to be worn for the rest of their lives. The continent ileostomy as devised by Kock provides the patient with an intraabdominal ileal reservoir and a valve constructed by invaginating the efferent ileal segment into the reservoir. The patient empties his reservoir 2 to 3 times a day by inserting a catheter through the valve. Our experience with 45 patients is reported. In most cases the continent ileostomy was constructed as a second procedure after proctocolectomy. The construction of a continent ileostomy as a secondary procedure can be recommended in patients with proctocolectomy. It offers patients a life situation differing only insignificantly from that of normal persons.

  5. A Review of Recent Developments in the Study of Regional Lithospheric Electrical Structure of the Asian Continent

    NASA Astrophysics Data System (ADS)

    Zhang, Letian

    2017-09-01

    The Asian continent was formed through the amalgamation of several major continental blocks that were formerly separated by the Paleo-Asian and Tethyan Oceans. During this process, the Asian continent underwent a long period of continental crustal growth and tectonic deformation, making it the largest and youngest continent on Earth. This paper presents a review of the application of geophysical electromagnetic methods, mainly the magnetotelluric (MT) method, in recent investigations of the diverse tectonic features across the Asian continent. The case studies cover the major continental blocks of Asia, the Central Asian orogenic system, the Tethyan orogenic system, as well as the western Pacific subduction system. In summary, most of the major continental blocks of Asia exhibit a three-layer structure with a resistive upper crust and upper mantle and a relatively conductive mid-lower crust. Large-scale conductors in the upper mantle were interpreted as an indication of lithospheric modification at the craton margins. The electrical structure of the Central Asian orogenic system is generally more resistive than the bordering continental blocks, whereas the Tethyan orogenic system displays more conductive, with pervasive conductors in the lower crust and upper mantle. The western Pacific subduction system shows increasing complexity in its electrical structure from its northern extent to its southern extent. In general, the following areas of the Asian continent have increasingly conductive lithospheric electrical structures, which correspond to a transition from the most stable areas to the most active tectonic areas of Asia: the major continental blocks, the accretionary Central Asian orogenic system, the collisional Tethyan orogenic system, and the western Pacific subduction system. As a key part of this review, a three-dimensional (3-D) model of the lithospheric electrical structure of a large portion of the Tibetan Plateau is presented and discussed in detail

  6. 21 CFR 876.5030 - Continent ileostomy catheter.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Continent ileostomy catheter. 876.5030 Section 876.5030 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Therapeutic Devices § 876.5030 Continent ileostomy...

  7. Plasmodium vivax Diversity and Population Structure across Four Continents

    PubMed Central

    Koepfli, Cristian; Rodrigues, Priscila T.; Antao, Tiago; Orjuela-Sánchez, Pamela; Van den Eede, Peter; Gamboa, Dionicia; van Hong, Nguyen; Bendezu, Jorge; Erhart, Annette; Barnadas, Céline; Ratsimbasoa, Arsène; Menard, Didier; Severini, Carlo; Menegon, Michela; Nour, Bakri Y. M.; Karunaweera, Nadira; Mueller, Ivo; Ferreira, Marcelo U.; Felger, Ingrid

    2015-01-01

    Plasmodium vivax is the geographically most widespread human malaria parasite. To analyze patterns of microsatellite diversity and population structure across countries of different transmission intensity, genotyping data from 11 microsatellite markers was either generated or compiled from 841 isolates from four continents collected in 1999–2008. Diversity was highest in South-East Asia (mean allelic richness 10.0–12.8), intermediate in the South Pacific (8.1–9.9) Madagascar and Sudan (7.9–8.4), and lowest in South America and Central Asia (5.5–7.2). A reduced panel of only 3 markers was sufficient to identify approx. 90% of all haplotypes in South Pacific, African and SE-Asian populations, but only 60–80% in Latin American populations, suggesting that typing of 2–6 markers, depending on the level of endemicity, is sufficient for epidemiological studies. Clustering analysis showed distinct clusters in Peru and Brazil, but little sub-structuring was observed within Africa, SE-Asia or the South Pacific. Isolates from Uzbekistan were exceptional, as a near-clonal parasite population was observed that was clearly separated from all other populations (F ST>0.2). Outside Central Asia F ST values were highest (0.11–0.16) between South American and all other populations, and lowest (0.04–0.07) between populations from South-East Asia and the South Pacific. These comparisons between P. vivax populations from four continents indicated that not only transmission intensity, but also geographical isolation affect diversity and population structure. However, the high effective population size results in slow changes of these parameters. This persistency must be taken into account when assessing the impact of control programs on the genetic structure of parasite populations. PMID:26125189

  8. Pregnancy after orthotopic continent urinary diversion.

    PubMed

    Kennedy, W A; Hensle, T W; Reiley, E A; Fox, H E; Haus, T

    1993-10-01

    Continent urinary diversion has become a common form of bladder management for the female exstrophy patient in whom primary reconstruction has failed. Reported are the results of successful pregnancies in four young adult females, who had previously undergone a flap vaginoplasty as part of earlier management and more recently a continent right colonic urinary reservoir with a perineal stoma (Indiana pouch). Pregnancy in each of these patients was characterized by several urinary tract infections, cervical prolapse and mild to severe maternal hydronephrosis. All of the patients had some degree of difficulty with clean intermittent catheterization. One patient required an indwelling catheter with prolonged bed rest. Maternal hydronephrosis resolved after delivery in all instances. All four patients delivered their infants by way of cesarean section, either emergently for maternal or fetal distress or electively. Cervical prolapse did not resolve in three patients and will require surgical repair. After delivery, all patients returned to their previous pattern of clean intermittent catheterization without loss of continence. All the infants delivered were healthy with appropriate weights and high Apgar scores (more than 8). Orthotopic (perineal stoma) continent urinary diversion is not a contraindication to pregnancy. However, our experience mandates delivery by cesarean section with close monitoring for maternal or fetal distress during gestation.

  9. Roos and NACP-02 ion chamber perturbations and water-air stopping-power ratios for clinical electron beams for energies from 4 to 22 MeV

    NASA Astrophysics Data System (ADS)

    Bailey, M.; Shipley, D. R.; Manning, J. W.

    2015-02-01

    Empirical fits are developed for depth-compensated wall- and cavity-replacement perturbations in the PTW Roos 34001 and IBA / Scanditronix NACP-02 parallel-plate ionisation chambers, for electron beam qualities from 4 to 22 MeV for depths up to approximately 1.1 × R50,D. These are based on calculations using the Monte Carlo radiation transport code EGSnrc and its user codes with a full simulation of the linac treatment head modelled using BEAMnrc. These fits are used with calculated restricted stopping-power ratios between air and water to match measured depth-dose distributions in water from an Elekta Synergy clinical linear accelerator at the UK National Physical Laboratory. Results compare well with those from recent publications and from the IPEM 2003 electron beam radiotherapy Code of Practice.

  10. Development and Validation of the Role Profile of the Nurse Continence Specialist: A Project of the International Continence Society.

    PubMed

    Paterson, Janice; Ostaszkiewicz, Joan; Suyasa, I Gede Putu Darma; Skelly, Jennifer; Bellefeuille, Lesley

    Although nurses have specialized in the management of incontinence, bladder, bowel, and pelvic floor dysfunction for more than 30 years, there is a lack of awareness and underutilization of their role. This article describes a 6-year project to define, characterize, and validate a role profile of the Nurse Continence Specialist. Data collection used a 2-phase, mixed-methods design. Phase 1 of the project resulted in a draft Nurse Continence Specialist role profile and Phase 2 led to validation of the draft profile. The result was a broad consensus about what constitutes the specific skill set for Nurse Continence Specialist specialization within nursing.

  11. 21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...

  12. 21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...

  13. 21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...

  14. 21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...

  15. 21 CFR 876.5280 - Implanted mechanical/hydraulic urinary continence device.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Implanted mechanical/hydraulic urinary continence....5280 Implanted mechanical/hydraulic urinary continence device. (a) Identification. An implanted mechanical/hydraulic urinary continence device is a device used to treat urinary incontinence by the...

  16. OxyContin: Prescription Drug Abuse. CSAT Advisory.

    ERIC Educational Resources Information Center

    Substance Abuse and Mental Health Services Administration (DHHS/PHS), Rockville, MD. Center for Substance Abuse Treatment.

    Recently, the media have issued numerous reports about the apparent increase in OxyContin abuse and addiction. OxyContin has been heralded as a miracle drug that allows patients with chronic pain to resume a normal life. It has also been called pharmaceutical heroin and is thought to have been responsible for a number of deaths and robberies in…

  17. Mid-rotation silviculture timing influences nitrogen mineralization of loblolly pine plantations in the mid-south USA

    Treesearch

    Michael A. Blazier; D. Andrew Scott; Ryan Coleman

    2015-01-01

    Intensively managed loblolly pine (Pinus taeda L.) plantations often develop nutrient deficiencies near mid-rotation. Common silvicultural treatments for improving stand nutrition at this stage include thinning, fertilization, and vegetation control. It is important to better understand the influence of timing fertilization and vegetation control...

  18. Combined Bladder Neck Reconstruction and Continent Stoma Creation as a Suitable Alternative for Continence in Bladder Exstrophy: a Preliminary Report.

    PubMed

    Kasprenski, Matthew; Benz, Karl; Jayman, John; Lue, Kathy; Maruf, Mahir; Baumgartner, Timothy; Gearhart, John

    2018-05-25

    To explore the use of concomitant BNR and creation of a continent stoma (CS) in patients that are not quite eligible for BNR, but still strongly desire volitional voiding. The authors retrospectively reviewed an institutional database of EEC patients for those who underwent BNR-CS between 2000 and 2015. Indications for a BNR-CS, perioperative outcomes, and continence status were evaluated. Method of voiding and continence status were analyzed for patients with greater than six months of follow-up after the BNR-CS. A total of 24 EEC patients (15 male and 9 female) underwent BNR-CS at a median age of 8.9 years (range 5.4-17.4). This included, 18 patients with classic bladder exstrophy (CBE), 5 with epispadias, and 1 with a cloacal exstrophy variant. There were 5 (20.1%) surgical complications following the BNR-CS, including 3 febrile urinary tract infections, 1 superficial wound infection, and 1 urethrocutaneous fistula. The median follow-up time from the time of BNR-CS was 1.1 years (range 0.1-14.1). Seventeen of 24 patients (71%) had a follow-up greater than 6 months and were evaluated for continence. Twelve patients (71%) were completely dry for intervals greater than 3 hours following BNR-CS. Five (29%) did not achieve continence with BNR-CS. Of those 5 patients, 3 (60%) underwent subsequent bladder neck transection. Combined BNR and CS is a suitable alternative to achieve urinary continence in patients that are not ideal candidates for BNR alone. This approach can offer a select group of patients the opportunity for volitional voiding. Copyright © 2018. Published by Elsevier Inc.

  19. Amplified summer warming in Europe-West Asia and Northeast Asia after the mid-1990s

    NASA Astrophysics Data System (ADS)

    Hong, Xiaowei; Lu, Riyu; Li, Shuanglin

    2017-09-01

    Regional temperature changes are a crucial factor in affecting agriculture, ecosystems and societies, which depend greatly on local temperatures. We identify a nonuniform warming pattern in summer around the mid-1990s over the Eurasian continent, with a predominant amplified warming over Europe-West Asia and Northeast Asia but much weaker warming over Central Asia. It is found that the nonuniform warming concurs with both the phase shift of the Atlantic Multi-decadal Oscillation (AMO) and the decadal change in the Silk Road Pattern (SRP), which is an upper-tropospheric teleconnection pattern over the Eurasian continent during summer. We suggest that the AMO may modulate the decadal change in SRP and then induce the zonal asymmetry in temperature changes. Our results have important implications for decadal prediction of regional warming pattern in Eurasia based on the predictable AMO.

  20. Mantle dynamics of continent-wide tilting of Australia

    NASA Astrophysics Data System (ADS)

    Dicaprio, L.; Gurnis, M.; Muller, R. D.

    2009-12-01

    Australia is distinctive in that during the Cenozoic it experienced first order, broad-scale vertical motions unrelated to normal orogenic processes. The progressive continent-wide tilting down to the northeast is attributed to the horizontal motion of the continent over subducted slabs. We use plate tectonic reconstructions and a model of mantle convection to quantitatively link the geological evolution of the continent to mantle convection. The passage of slabs beneath the Southwest Pacific since 50 Ma is modeled numerically, and the results are compared to geologic observations of anomalous topography. Models show that Australia undergoes a 300 m northeast downward tilt as it approaches and overrides subducted slabs between Melanesia and the active margin along the Loyalty and proto-Tonga Kermadec subduction systems. This pattern of dynamic subsidence is consistent with observations of continent wide tilting and may indicate that during the Cenozoic Australia moved northward away from a relatively hot mantle anomaly presently located beneath Antarctica.

  1. Simulation of active tectonic processes for a convecting mantle with moving continents

    USGS Publications Warehouse

    Trubitsyn, V.; Kaban, M.; Mooney, W.; Reigber, C.; Schwintzer, P.

    2006-01-01

    Numerical models are presented that simulate several active tectonic processes. These models include a continent that is thermally and mechanically coupled with viscous mantle flow. The assumption of rigid continents allows use of solid body equations to describe the continents' motion and to calculate their velocities. The starting point is a quasi-steady state model of mantle convection with temperature/ pressure-dependent viscosity. After placing a continent on top of the mantle, the convection pattern changes. The mantle flow subsequently passes through several stages, eventually resembling the mantle structure under present-day continents: (a) Extension tectonics and marginal basins form on boundary of a continent approaching to subduction zone, roll back of subduction takes place in front of moving continent; (b) The continent reaches the subduction zone, the extension regime at the continental edge is replaced by strong compression. The roll back of the subduction zone still continues after closure of the marginal basin and the continent moves towards the upwelling. As a result the ocean becomes non-symmetric and (c) The continent overrides the upwelling and subduction in its classical form stops. The third stage appears only in the upper mantle model with localized upwellings. ?? 2006 The Authors Journal compilation ?? 2006 RAS.

  2. Onset of oxidative weathering of continents recorded in the geochemistry of ancient glacial diamictites

    NASA Astrophysics Data System (ADS)

    Gaschnig, Richard M.; Rudnick, Roberta L.; McDonough, William F.; Kaufman, Alan J.; Hu, Zhaochu; Gao, Shan

    2014-12-01

    Glacial diamictites deposited in the Mesoarchean, Paleoproterozoic, Neoproterozoic, and Paleozoic eras record temporal variations in their average compositions that reflect the changing composition of the upper continental crust (UCC). Twenty six of the 27 units studied show elevated chemical index of alternation (CIA) and low Sr abundances, regardless of their age, documenting pervasive weathering of the average UCC. Lower abundances of transition metals reflect a shift towards more felsic crustal compositions after the Archean. Superimposed on this chemical difference is the signal of the rise of oxidative weathering of the continents, recorded by changes in the absolute and relative abundances of the redox sensitive elements Mo and V. Neoproterozoic and Paleozoic diamictites show pervasive depletion in Mo and V, reflecting their loss from the continents due to increasing intensity of oxidative weathering, as also recorded in some of the Paleoproterozoic diamictites. A few of the Paleoproterozoic diamictites deposited after the Great Oxidation Event show no depletion in Mo and V (e.g., Gowganda), but such signatures could be inherited from their provenance. In contrast, the pre-GOE Duitschland diamictite (ca. 2.3-2.5 Ga) from South Africa reveals evidence of intense oxidative weathering (i.e., large depletions in Mo), supporting a growing body of observations showing the presence of measurable atmospheric oxygen prior to permanent loss of the mass independent fractionation signal in sulfur isotopes.

  3. Urethral pressure response patterns induced by squeeze in continent and incontinent women.

    PubMed

    Teleman, Pia M; Mattiasson, Anders

    2007-09-01

    Our aim was to compare the urethral pressure response pattern to pelvic floor muscle contractions in 20-27 years old, nulliparous continent women (n = 31) to that of continent (n = 28) and formerly untreated incontinent (n = 59) (53-63 years old) women. These women underwent urethral pressure measurements during rest and repeated pelvic muscle contractions. The response to the contractions was graded 0-4. The young continent women showed a mean urethral pressure response of 2.8, the middle-aged continent women 2.2 (NS vs young continent), and the incontinent women 1.5 (p < 0.05 vs middle-aged continent, p < 0.001 vs young continent). Urethral pressures during rest were significantly higher in the younger women than in both groups of middle-aged women. The decreased ability to increase urethral pressure on demand seen in middle-aged incontinent women compared to continent women of the same age as well as young women seems to be a consequence of a neuromuscular disorder rather than of age.

  4. Influence of disease on population model of mid-continent mallards

    USGS Publications Warehouse

    Samuel, Michael D.

    1992-01-01

    , seek seclusion in dense cover and are removed by efficient predators or scavengers prior to human detection. Our objective was to evaluate the possible effects of three of the most common diseases (friend 1985), avian cholera, avian botulism and lead poisoning, on the population dynamics of mid-continental mallards. We used data from disease outbreaks to develop preliminary estimates of mortality rates and their temporal pattern. A computer model was used to integrate these mortality estimate with other mallard life history characteristics, evaluate the potential effects of these diseases on mallard demographics and assess the need for better information on the effects of disease on mallards.

  5. The ContiNet of the International Continence Society.

    PubMed

    Lim, P H; Fonda, D

    1997-01-01

    This is an account of the International Continence Society's ContiNet--the web server linking up continence organisations worldwide with provision to upload or download vast data stores of information on continence via e-mail, FTP, mailing lists, and special tools to seek information using "search engines." Special communication devices using internet voice/phone mail and real-time "text" or "voice" chats permit conversation globally over normal phone lines linked to the Net at local telephone rates. Special features of ContiNet include announcements of upcoming conventions, information for professionals and laypeople, and the capability to conduct research via the net and conduct consultations and discussions via newsgroups. In-built devices requiring special IDs and passwords permit privacy and security for users. Simple instructions are provided on how to get your PC up and running and get connected to fellow members of ICS, link up with national continence societies, or simply surf for professional enrichment and leisure. With the advent of advanced multimedia capabilities, the current poor quality videoconferencing on the Net will be replaced by excellent videophones by 1998.

  6. A Geological Model for the Evolution of Early Continents (Invited)

    NASA Astrophysics Data System (ADS)

    Rey, P. F.; Coltice, N.; Flament, N. E.; Thébaud, N.

    2013-12-01

    Geochemical probing of ancient sediments (REE in black shales, strontium composition of carbonates, oxygen isotopes in zircons...) suggests that continents were a late Archean addition at Earth's surface. Yet, geochemical probing of ancient basalts reveals that they were extracted from a mantle depleted of its crustal elements early in the Archean. Considerations on surface geology, the early Earth hypsometry and the rheology and density structure of Archean continents can help solve this paradox. Surface geology: The surface geology of Archean cratons is characterized by thick continental flood basalts (CFBs, including greenstones) emplaced on felsic crusts dominated by Trondhjemite-Tonalite-Granodiorite (TTG) granitoids. This simple geology is peculiar because i/ most CFBs were emplaced below sea level, ii/ after their emplacement, CFBs were deformed into relatively narrow, curviplanar belts (greenstone basins) wrapping around migmatitic TTG domes, and iii/ Archean greenstone belts are richly endowed with gold and other metals deposits. Flat Earth hypothesis: From considerations on early Earth continental geotherm and density structure, Rey and Coltice (2008) propose that, because of the increased ability of the lithosphere to flow laterally, orogenic processes in the Archean produced only subdued topography (continents, Flament et al. (2008) proposed a theory for the hypsometry of the early Earth showing that, until the late Archean, most continents were flooded and Earth was largely a water world. From this, a model consistent with many of the peculiar attributes of Archean geology, can be proposed: 1/ Continents appeared at Earth's surface at an early stage during the Hadean/Archean. However, because they were i/ covered by continental flood basalts, ii/ below sea level, and iii/ deprived of modern-style mountain belts and orogenic plateaux, early felsic

  7. 21 CFR 876.5310 - Nonimplanted, peripheral electrical continence device.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... a peripheral location and used to stimulate the nerves associated with pelvic floor function to... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Nonimplanted, peripheral electrical continence....5310 Nonimplanted, peripheral electrical continence device. (a) Identification. A nonimplanted...

  8. Our changing continent

    USGS Publications Warehouse

    ,

    1969-01-01

    Where were the land areas and oceans of the North American Continent one million years ago, compared to our present geography? Was North America always about the same size and shape as it is today? To answer these questions, we must construct maps of the lands and sea that existed during the past ages. This process of reconstructing ancient geography is called paleogeography (from the Greek word "palaios," meaning ancient).

  9. Geographic distribution of the mid-continent population of sandhill cranes and related management applications

    USGS Publications Warehouse

    Krapu, Gary L.; Brandt, David A.; Jones, Kenneth L.; Johnson, Douglas H.

    2011-01-01

    The Mid-continent Population (MCP) of sandhill cranes (Grus canadensis) is widely hunted in North America and is separated into the Gulf Coast Subpopulation and Western Subpopulation for management purposes. Effective harvest management of the MCP requires detailed knowledge of breeding distribution of subspecies and subpopulations, chronology of their use of fall staging areas and wintering grounds, and exposure to and harvest from hunting. To address these information needs, we tagged 153 sandhill cranes with Platform Transmitting Terminals (PTTs) during 22 February–12 April 1998–2003 in the Central and North Platte River valleys of south-central Nebraska. We monitored PTT-tagged sandhill cranes, hereafter tagged cranes, from their arrival to departure from breeding grounds, during their fall migration, and throughout winter using the Argos satellite tracking system. The tracking effort yielded 74,041 useable locations over 49,350 tag days; median duration of tracking of individual cranes was 352 days and 73 cranes were tracked >12 months. Genetic sequencing of mitochondrial DNA (mtDNA) from blood samples taken from each of our random sample of tagged cranes indicated 64% were G. c. canadensis and 34% were Grus canadensis tabida. Tagged cranes during the breeding season settled in northern temperate, subarctic, and arctic North America (U.S. [23%, n = 35], Canada [57%, n = 87]) and arctic regions of northeast Asia (Russia [20%, n = 31]). Distribution of tagged cranes by breeding affiliation was as follows: Western Alaska–Siberia (WA–S, 42 ± 4% [SE]), northern Canada–Nunavut (NC–N, 21 ± 4%), west-central Canada–Alaska (WC–A, 23 ± 4%) and East-central Canada–Minnesota (EC–M, 14 ± 3%). All tagged cranes returned to the same breeding affiliation used during the previous year with a median distance of 1.60 km (range: 0.08–7.7 km, n = 53) separating sites used in year 1 and year 2. Fall staging occurred

  10. 21 CFR 876.5270 - Implanted electrical urinary continence device.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Implanted electrical urinary continence device... Implanted electrical urinary continence device. (a) Identification. An implanted electrical urinary device is a device intended for treatment of urinary incontinence that consists of a receiver implanted in...

  11. 21 CFR 876.5270 - Implanted electrical urinary continence device.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 8 2011-04-01 2011-04-01 false Implanted electrical urinary continence device... Implanted electrical urinary continence device. (a) Identification. An implanted electrical urinary device is a device intended for treatment of urinary incontinence that consists of a receiver implanted in...

  12. 21 CFR 876.5270 - Implanted electrical urinary continence device.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 8 2012-04-01 2012-04-01 false Implanted electrical urinary continence device... Implanted electrical urinary continence device. (a) Identification. An implanted electrical urinary device is a device intended for treatment of urinary incontinence that consists of a receiver implanted in...

  13. 21 CFR 876.5270 - Implanted electrical urinary continence device.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 8 2013-04-01 2013-04-01 false Implanted electrical urinary continence device... Implanted electrical urinary continence device. (a) Identification. An implanted electrical urinary device is a device intended for treatment of urinary incontinence that consists of a receiver implanted in...

  14. 21 CFR 876.5270 - Implanted electrical urinary continence device.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Implanted electrical urinary continence device. (a) Identification. An implanted electrical urinary device is a device intended for treatment of urinary incontinence that consists of a receiver implanted in... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Implanted electrical urinary continence device...

  15. Sublatitudinal Isotope Heterogeneity of The Atlantic and Adjacent Continents: A Relation To The Litospheric Plates and Superplums

    NASA Astrophysics Data System (ADS)

    Mironov, Yu. V.; Ryakhovsky, V. M.; Pustovoy, A. A.; Lapidus, I. V.

    Four Sr-Nd-Pb isotope sublatitudinal provinces are chosen in the Atlantic and on ad- jacent continents. They include mid-ocean ridges, oceanic rises and islands, as well as Late Mesozoic - Cenozoic continental rifts and traps. A modified Zindler-Hart "man- tle tetrahedron" (1986) have been used for rock systematics. Its major classification element alongside with known end-members (DM, HIMU, EM1, EM2) is any in- tratetrahedron component F ("focal") (Mironov et al., 2000; Rundquist et al., 2000; Ryakhovsky, 2000). It represents average characteristic of all known intratetrahedron components (FOZO, C, PREMA etc.), updated by methods of multidimensional statis- tics. Northern province includes Mid-Atlantic Ridge from a southern part of Reykjanes ridge up to 24S, numerous islands and rises, located at the same latitudes, Cameroon Line, African and European rifts, Aden and Red sea spreading centres, and also Co- mores in Indian ocean. The main composition dispersion of volcanics from withinplate oceanic and continental structures is determined by mixture of F and HIMU (rarely with admixture EM2). MORB within this area are characterized by stable admixture HIMU. Similar composition have the rocks in Bouvet-Antarctic province, within the limits of which the rises Spiss and Shona, the most southern part of Mid-Atlantic ridge, island Bouvet, an adjacent part of Southwest-Indian Ridge, and also traps and rifts on northern coast of Antarctic Continent are located. The Southern province lies in outlines of known Southern hemisphere DUPAL-anomaly (Hart, 1984). The with- inplate oceanic rocks (Gough, Tristan-da-Kunha, Walvis ridge, Rio Grande Plateau, Discovery) correspond to a mixture F + EM1 (sometimes F + EM1 + EM2) and are similar with traps of Southern America and Africa. Further to east this province is traced on islands and mid-ocean ridges in Indian ocean. MORB of Southern Atlantic and Indian ocean are enriched EM1. The Arctic province includes spreading ridges of

  16. Regulating continent growth and composition by chemical weathering

    PubMed Central

    Lee, Cin-Ty Aeolus; Morton, Douglas M.; Little, Mark G.; Kistler, Ronald; Horodyskyj, Ulyana N.; Leeman, William P.; Agranier, Arnaud

    2008-01-01

    Continents ride high above the ocean floor because they are underlain by thick, low-density, Si-rich, and Mg-poor crust. However, the parental magmas of continents were basaltic, which means they must have lost Mg relative to Si during their maturation into continents. Igneous differentiation followed by lower crustal delamination and chemical weathering followed by subduction recycling are possible solutions, but the relative magnitudes of each process have never been quantitatively constrained because of the lack of appropriate data. Here, we show that the relative contributions of these processes can be obtained by simultaneous examination of Mg and Li (an analog for Mg) on the regional and global scales in arcs, delaminated lower crust, and river waters. At least 20% of Mg is lost from continents by weathering, which translates into >20% of continental mass lost by weathering (40% by delamination). Chemical weathering leaves behind a more Si-rich and Mg-poor crust, which is less dense and hence decreases the probability of crustal recycling by subduction. Net continental growth is thus modulated by chemical weathering and likely influenced by secular changes in weathering mechanisms. PMID:18362343

  17. Regulating continent growth and composition by chemical weathering

    USGS Publications Warehouse

    Lee, C.-T.A.; Morton, D.M.; Little, M.G.; Kistler, R.; Horodyskyj, U.N.; Leeman, W.P.; Agranier, A.

    2008-01-01

    Continents ride high above the ocean floor because they are underlain by thick, low-density, Si-rich, and Mg-poor crust. However, the parental magmas of continents were basaltic, which means they must have lost Mg relative to Si during their maturation into continents. Igneous differentiation followed by lower crustal delamination and chemical weathering followed by subduction recycling are possible solutions, but the relative magnitudes of each process have never been quantitatively constrained because of the lack of appropriate data. Here, we show that the relative contributions of these processes can be obtained by simultaneous examination of Mg and Li (an analog for Mg) on the regional and global scales in arcs, delaminated lower crust, and river waters. At least 20% of Mg is lost from continents by weathering, which translates into >20% of continental mass lost by weathering (40% by delamination). Chemical weathering leaves behind a more Si-rich and Mg-poor crust, which is less dense and hence decreases the probability of crustal recycling by subduction. Net continental growth is thus modulated by chemical weathering and likely influenced by secular changes in weathering mechanisms. ?? 2008 by The National Academy of Sciences of the USA.

  18. Regional climate projection of the Maritime Continent using the MIT Regional Climate Model

    NASA Astrophysics Data System (ADS)

    IM, E. S.; Eltahir, E. A. B.

    2014-12-01

    Given that warming of the climate system is unequivocal (IPCC AR5), accurate assessment of future climate is essential to understand the impact of climate change due to global warming. Modelling the climate change of the Maritime Continent is particularly challenge, showing a high degree of uncertainty. Compared to other regions, model agreement of future projections in response to anthropogenic emission forcings is much less. Furthermore, the spatial and temporal behaviors of climate projections seem to vary significantly due to a complex geographical condition and a wide range of scale interactions. For the fine-scale climate information (27 km) suitable for representing the complexity of climate change over the Maritime Continent, dynamical downscaling is performed using the MIT regional climate model (MRCM) during two thirty-year period for reference (1970-1999) and future (2070-2099) climate. Initial and boundary conditions are provided by Community Earth System Model (CESM) simulations under the emission scenarios projected by MIT Integrated Global System Model (IGSM). Changes in mean climate as well as the frequency and intensity of extreme climate events are investigated at various temporal and spatial scales. Our analysis is primarily centered on the different behavior of changes in convective and large-scale precipitation over land vs. ocean during dry vs. wet season. In addition, we attempt to find the added value to downscaled results over the Maritime Continent through the comparison between MRCM and CESM projection. Acknowledgements.This research was supported by the National Research Foundation Singapore through the Singapore MIT Alliance for Research and Technology's Center for Environmental Sensing and Modeling interdisciplinary research program.

  19. Continent women have better urethral neuromuscular function than those with stress incontinence

    PubMed Central

    Mueller, Elizabeth; Brubaker, Linda

    2012-01-01

    Introduction and hypothesis The objective of this study is to describe urethral neuromuscular function using concentric needle electromyography (EMG) in stress incontinent (SUI) and asymptomatic women. Methods Following Institutional Review Board approval, we recruited SUI and asymptomatic women without urinary incontinence. Participants underwent quantitative urethral EMG and urodynamic testing. Results Sixty-seven women (37 SUI, 30 continent) with mean±SD age of 44±12 years participated. Nearly all EMG parameters showed significant differences between continent and SUI women consistent with better motor unit recruitment in continent women. Continent women had larger-amplitude, longer-duration motor unit action potentials (MUP) with increased turns and better MUP recruitment during bladder filling (P<.05). Increasing age was inversely correlated with nearly all MUP parameters (P<.05), suggesting MUP to be consistent with neuropathy. Conclusions We found significant differences in multiple MUP parameters in urethral sphincter between continent and stress incontinent women, suggesting continent women have better urethral innervation. We also found significant neuropathic MUP changes with advancing age, regardless of continence status. PMID:21979386

  20. Nonlinear photothermal Mid-Infrared Microspectroscopy with Superresolution

    NASA Astrophysics Data System (ADS)

    Erramilli, Shyamsunder; Mertiri, Alket; Liu, Hui; Totachawattana, Atcha; Hong, Mi; Sander, Michelle

    2015-03-01

    We describe a nonlinear method for breaking the diffraction limit in mid-infrared microscopy using nonlinear photothermal microspectroscopy. A Quantum Cascade Laser (QCL) tuned to an infrared active vibrational molecular normal mode is used as the pump laser. A low-phase noise Erbium-doped fiber (EDFL) laser is used as the probe. When the incident intensity of the mid-infrared pump laser is increased past a critical threshold, a nanobubble is nucleated, strongly modulating the scatter of the probe beam, in agreement with prior work. Remarkably, we have also found that the photothermal spectral signature of the mid-infrared absorption bifurcates and is strongly narrowed, consistent with an effective ``mean-field'' theory of the observed pitchfork bifurcation. This ultrasharp narrowing can be exploited to obtain mid-infrared images with a resolution that breaks the diffraction limit, without the need of mechanical scanning near-field probes. The method provides a powerful new tool for hyperspectral label-free mid-infrared imaging and characterization of biological tissues and materials science and engineering. We thank our collaborators H. Altug, L. D. Ziegler, J. Mertz, for their advice and generous loan of equipment.

  1. Preferential rifting of continents - A source of displaced terranes

    NASA Technical Reports Server (NTRS)

    Vink, G. E.; Morgan, W. J.; Zhao, W.-L.

    1984-01-01

    Lithospheric rifting, while prevalent in the continents, rarely occurs in oceanic regions. To explain this preferential rifting of continents, the total strength of different lithospheres is compared by integrating the limits of lithospheric stress with depth. Comparisons of total strength indicate that continental lithosphere is weaker than oceanic lithosphere by about a factor of three. Also, a thickened crust can halve the total strength of normal continental lithosphere. Because the weakest area acts as a stress guide, any rifting close to an ocean-continent boundary would prefer a continental pathway. This results in the formation of small continental fragments or microplates that, once accreted back to a continent during subduction, are seen as displaced terranes. In addition, the large crustal thicknesses associated with suture zones would make such areas likely locations for future rifting episodes. This results in the tendency of new oceans to open along the suture where a former ocean had closed.

  2. The impact of cavernosal nerve preservation on continence after robotic radical prostatectomy

    PubMed Central

    Pick, Donald L.; Osann, Kathryn; Skarecky, Douglas; Narula, Navneet; Finley, David S.; Ahlering, Thomas E.

    2014-01-01

    OBJECTIVE To evaluate associations between baseline characteristics, nerve-sparing (NS) status and return of continence, as a relationship may exist between return to continence and preservation of the neurovascular bundles for potency during radical prostatectomy (RP). PATIENTS AND METHODS The study included 592 consecutive robotic RPs completed between 2002 and 2007. All data were entered prospectively into an electronic database. Continence data (defined as zero pads) was collected using self-administered validated questionnaires. Baseline characteristics (age, International Index of Erectile Function [IIEF-5] score, American Urological Association symptom score, body mass index [BMI], clinical T-stage, Gleason score, and prostate-specific antigen level), NS status and learning curve were retrospectively evaluated for association with overall continence at 1, 3 and 12 months after RP using univariate and multivariable methods. Any patient taking preoperative phosphodiesterase inhibitors was excluded from the postoperative analysis. RESULTS Complete data were available for 537 of 592 patients (91%). Continence rates at 12 months after RP were 89.2%, 88.9% and 84.8% for bilateral NS, unilateral NS and non-NS respectively (P = 0.56). In multivariable analysis age, IIEF-5 score and BMI were significant independent predictors of continence. Cavernosal NS status did not significantly affect continence after adjusting for other co-variables. CONCLUSION After careful multivariable analysis of baseline characteristics age, IIEF-5 score and BMI affected continence in a statistically significant fashion. This suggests that baseline factors and not the physical preservation of the cavernosal nerves predict overall return to continence. PMID:21244602

  3. Intoxication and binge and high-intensity drinking among US young adults in their mid-20s.

    PubMed

    Terry-McElrath, Yvonne M; Patrick, Megan E

    2016-01-01

    Alcohol use is a key risk factor for young adult mortality and disease, but limited research has focused on high-risk alcohol use among individuals moving from early young adulthood into building and maintaining an initial structure of adult life. This study estimated the prevalence of a range of alcohol use behaviors among US young adults aged 25/26, examined evidence for historical change in prevalence rates, and estimated associations between alcohol use and key demographic, substance use, and adult social role characteristics. Data were obtained from 3542 individuals selected for follow-up from the nationally representative 12th-grade student Monitoring the Future study. Respondents self-reported alcohol use behaviors at age 25/26 during calendar years 2005-2014. Two fifths (39.9%) of young adults aged 25/26 reported being intoxicated at least once in the past 30 days; 25.6% reported usually experiencing a sustained high of 3 or more hours when drinking alcohol. Past-2-week binge drinking (5+ drinks in a row) was reported by 36.3% of respondents. Past-2-week high-intensity drinking (10+ drinks in a row) was reported by 12.4%. These age 25/26 alcohol use prevalence rates remained stable over the 10 years of data examined, in contrast to significant declines over historical time in alcohol prevalence rates among these same individuals at age 18. High-risk drinking was particularly associated with being male, white, unmarried, employed, a nonparent, and an alcohol user before finishing high school. Among US young adults in their mid-20s, alcohol use was highly normative and frequently included participation in high-risk drinking behaviors. High-risk alcohol use prevention approaches developed specifically to reach young adults in their mid-20s are needed, as well as efforts to increase proactive clinician screening to identify young adults participating in high-risk alcohol use.

  4. Intraplate mountain building in response to continent continent collision—the Ancestral Rocky Mountains (North America) and inferences drawn from the Tien Shan (Central Asia)

    NASA Astrophysics Data System (ADS)

    Dickerson, Patricia Wood

    2003-04-01

    The intraplate Ancestral Rocky Mountains of western North America extend from British Columbia, Canada, to Chihuahua, Mexico, and formed during Early Carboniferous through Early Permian time in response to continent-continent collision of Laurentia with Gondwana—the conjoined masses of Africa and South America, including Yucatán and Florida. Uplifts and flanking basins also formed within the Laurentian Midcontinent. On the Gondwanan continent, well inboard from the marginal fold belts, a counterpart structural array developed during the same period. Intraplate deformation began when full collisional plate coupling had been achieved along the continental margin; the intervening ocean had been closed and subduction had ceased—that is, the distinction between upper versus lower plates became moot. Ancestral Rockies deformation was not accompanied by volcanism. Basement shear zones that formed during Mesoproterozoic rifting of Laurentia were reactivated and exerted significant control on the locations, orientations, and modes of displacement on late Paleozoic faults. Ancestral Rocky Mountain uplifts extend as far south as Chihuahua and west Texas (28° to 33°N, 102° to 109°W) and include the Florida-Moyotes, Placer de Guadalupe-Carrizalillo, Ojinaga-Tascotal and Hueco Mountain blocks, as well as the Diablo and Central Basin Platforms. All are cored with Laurentian Proterozoic crystalline basement rocks and host correlative Paleozoic stratigraphic successions. Pre-late Paleozoic deformational, thermal, and metamorphic histories are similar as well. Southern Ancestral Rocky Mountain structures terminate along a line that trends approximately N 40°E (present coordinates), a common orientation for Mesoproterozoic extensional structures throughout southern to central North America. Continuing Tien Shan intraplate deformation (Central Asia) has created an analogous array of uplifts and basins in response to the collision of India with Eurasia, beginning in late

  5. Bladder continence management in adult acquired brain injury.

    PubMed

    Caldwell, Sheena B; Wilson, Jennifer S; Smith, Daniel; McCann, John P; Walsh, Ian K

    2014-01-01

    Persistence of urinary incontinence post acquired brain injury (ABI) carries important prognostic significance. We undertook to document the incidence of urinary incontinence, its management and complications in rehabilitation inpatients following ABI and to assess adherence to post ABI bladder management guidelines. A retrospective chart survey of a convenience sample of consecutive admissions to two adult neurorehabilitation units Forster Green Hospital, Belfast, and the Scottish Brain Injury Rehabilitation Service, Edinburgh (SBIRSE). Bladder continence and management on transfer to and discharge from rehabilitation, trial removal of catheter, use of bladder drill, ultrasound investigation, anticholinergic medication and complications were recorded. One hundred and forty six patients were identified. Seventy-seven (52.7%) were independent and continent of urine at rehabilitation admission and 109 (74.7%) on discharge. In all, 13 patients had urinary tract infection, 7 had urethral stricture and 1 developed haematuria whilst catheterised. Ultrasound of renal tracts was underused. Trial removal of catheter after transfer to rehabilitation occurred at a median of 10 days. Urinary continence was achieved in almost half of incontinent ABI patients during rehabilitation. There is potential for increased use of investigation of the renal tracts. Rehabilitation physicians should consider urethral stricture in the management of continence post ABI.

  6. Continent vesicovaginal fistula

    PubMed Central

    de Toledo, Luís Gustavo Morato; Santos, Victor Espinheira; Maron, Paulo Eduardo Gourlat; Vedovato, Bruno César; Fucs, Moacyr; Perez, Marjo Deninson Cardenuto

    2013-01-01

    ABSTRACT Vesicovaginal fistula is an abnormal communication between the bladder and vagina and represents the most frequent type of fistula in the urinary tract. The most common cause in Brazil is iatrogenic fistula, secondary to histerectomia. Classically these women present continuous urinary leakage from the vagina and absence of micturition, with strong negative impact on their quality of life. We present a case of totally continent vesicovaginal fistula, with a follow-up of 11 years with no complications. PMID:23579756

  7. Dentin remineralization in acid challenge environment via PAMAM and calcium phosphate composite.

    PubMed

    Liang, Kunneng; Weir, Michael D; Xie, Xianju; Wang, Lin; Reynolds, Mark A; Li, Jiyao; Xu, Hockin H K

    2016-11-01

    The objective of this study was to investigate the effects of poly (amido amine) (PAMAM), composite with nanoparticles of amorphous calcium phosphate (NACP), and the combined PAMAM+NACP nanocomposite treatment, on remineralization of demineralized dentin in a cyclic artificial saliva/lactic acid environment for the first time. Dentin specimens were prepared and demineralized with 37% phosphoric acid for 15s. Four groups were prepared: (1) dentin control, (2) dentin coated with PAMAM, (3) dentin with NACP composite, (4) dentin with PAMAM+NACP. Specimens were treated with a cyclic artificial saliva/lactic acid regimen for 21days. Acid neutralization and calcium (Ca) and phosphate (P) ion concentrations were measured. The remineralized dentin specimens were examined by scanning electron microscopy (SEM) and hardness testing. NACP nanocomposite had mechanical properties similar to commercial control composites (p>0.1). NACP composite had acid-neutralization and Ca and P ion release capability. PAMAM or NACP composite each alone achieved remineralization and increased the hardness of demineralized dentin (p<0.05). PAMAM+NACP nanocomposite achieved the greatest mineral regeneration in demineralized dentin and the greatest hardness increase in demineralized dentin, which approached the hardness of healthy dentin (p>0.1). The superior remineralization efficacy of PAMAM+NACP was demonstrated for the first time. PAMAM+NACP induced remineralization in demineralized dentin in an acid challenge environment, when conventional remineralization methods such as PAMAM did not work well. The novel PAMAM+NACP composite approach is promising for a wide range of dental applications to inhibit caries and protect tooth structures. Copyright © 2016 The Academy of Dental Materials. Published by Elsevier Ltd. All rights reserved.

  8. Investigation of giant Kerr nonlinearity in quantum cascade lasers using mid-infrared femtosecond pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cai, Hong; Liu, Sheng; Department of Physics, University of Maryland, Baltimore County

    2015-02-02

    We study the Kerr nonlinearity of quantum cascade lasers (QCLs) by coupling resonant and off-resonant mid-infrared (mid-IR) femtosecond (fs) pulses into an active QCL waveguide. We observe an increase in the spectral width of the transmitted fs pulses as the coupled mid-infrared (mid-IR) pulse power increases. This is explained by the self-phase modulation effect due to the large Kerr nonlinearity of QCL waveguides. We further confirm this effect by observing the intensity dependent far-field profile of the transmitted mid-IR pulses, showing the pulses undergo self-focusing as they propagate through the active QCL due to the intensity dependent refractive index. Wemore » experimentally estimate the nonlinear refractive index n{sub 2} of a QCL to be ∼8 × 10{sup −9 }cm{sup 2}/W using the far-field beam profile of the transmitted pulses. The finite-difference time-domain simulations of QCL waveguides with Kerr nonlinearity incorporated show similar behavior to the experimental results.« less

  9. Continence technologies whitepaper: Informing new engineering science research.

    PubMed

    Culmer, Pete; Alazmani, Ali; Bryant, Mike; Mancuso, Elena; King, Sarah; Mapunde, Vee; Jeays-Ward, Katherine; Heron, Nicola; Pearson, Russell; Vollebregt, Paul F; Corner, Lynne; Day, Richard

    2018-06-01

    Advances in healthcare technology for continence have historically been limited compared to other areas of medicine, reflecting the complexities of the condition and social stigma which act as a barrier to participation. This whitepaper has been developed to inspire and direct the engineering science community towards research opportunities that exist for continence technologies that address unmet needs in diagnosis, treatment and long-term management. Our aim is to pinpoint key challenges and highlight related research opportunities for novel technological advances. To do so, we draw on experience and expertise from academics, clinicians, patients and patient groups linked to continence healthcare. This is presented in four areas of consideration: the clinical pathway, patient perspective, research challenges and effective innovation. In each we introduce seminal research, background information and demonstrative case-studies, before discussing their relevance to engineering science researchers who are interested in approaching this overlooked but vital area of healthcare.

  10. Representations of OxyContin in North American newspapers and medical journals

    PubMed Central

    Whelan, Emma; Asbridge, Mark; Haydt, Susan

    2011-01-01

    BACKGROUND: There are public concerns regarding OxyContin (Purdue Pharma, Canada) and charges within the pain medicine community that media coverage of the drug has been biased. OBJECTIVE: To analyze and compare representations of OxyContin in medical journals and North American newspapers in an attempt to shed light on how each contributes to the ‘social problem’ associated with OxyContin. METHODS: Using searches of newspaper and medical literature databases, two samples were drawn: 924 stories published between 1995 and 2005 in 27 North American newspapers, and 197 articles published between 1995 and 2007 in 33 medical journals in the fields of addiction/substance abuse, pain/anesthesiology and general/internal medicine. The foci, themes, perspectives represented and evaluations of OxyContin presented in these texts were analyzed statistically. RESULTS: Newspaper coverage of OxyContin emphasized negative evaluations of the drug, focusing on abuse, addiction, crime and death rather than the use of OxyContin for the legitimate treatment of pain. Newspaper stories most often conveyed the perspectives of law enforcement and courts, and much less often represented the perspectives of physicians. However, analysis of physician perspectives represented in newspaper stories and in medical journals revealed a high degree of inconsistency, especially across the fields of pain medicine and addiction medicine. CONCLUSION: The prevalence of negative representations of OxyContin is often blamed on biased media coverage and an ignorant public. However, the proliferation of inconsistent messages regarding the drug from physicians plays a role in the drug’s persistent status as a social problem. PMID:22059195

  11. Enhanced removal of humic acid from aqueous solution by novel stabilized nano-amorphous calcium phosphate: Behaviors and mechanisms

    NASA Astrophysics Data System (ADS)

    Jiang, Ling; Li, Yiming; Shao, Yi; Zhang, Yong; Han, Ruiming; Li, Shiyin; Wei, Wei

    2018-01-01

    Stabilized nano-amorphous calcium phosphate (nACP) was prepared using polyethylene glycol as stabilizer to obtain a nanosized amorphous adsorbent. The produced nACP was evaluated by using XRD, FTIR, SEM and X-ray photoelectron spectroscopy (XPS). The sedimentation test demonstrated that nACP exhibited better stability than crystallized hydroxyapatite. The adsorption efficiency of the nACP material for aqueous humic acid (HA) was evaluated from the point of view of medium pH, adsorption time, temperature, and ionic strength, as well as the presences of metal ions. The results of the study showed very good adsorption performance towards aqueous HA. The Sips modeling results revealed that the stabilized nACP adsorbent had a considerably high adsorption capacity (248.3 mg/g) for HA at 298 K. The adsorption data fitted well into pseudo-second order and Elovich kinetic models. XPS analyses indicated that HA retention on nACP material might be due to the surface complexation reaction between oxygen-containing group and calcium of HA and nACP, respectively. Moreover, the HA adsorption capacity of nACP could still keep more than 86% after four adsorption-desorption cycles. By taking into account all results it was concluded that the nACP adsorbent leveraged its stability in combination with its high uptake capacity to offer a great promise for HA adsorption from water.

  12. Evaluation of antibacterial and remineralizing nanocomposite and adhesive in rat tooth cavity model

    PubMed Central

    Li, Fang; Wang, Ping; Weir, Michael D.; Fouad, Ashraf F.; Xu, Hockin H. K.

    2014-01-01

    Antibacterial and remineralizing dental composites and adhesives were recently developed to inhibit biofilm acids and combat secondary caries. It is not clear what effect these materials will have on dental pulps in vivo. The objectives of this study were to investigate the antibacterial and remineralizing restorations in a rat tooth cavity model, and determine pulpal inflammatory response and tertiary dentin formation. Nanoparticles of amorphous calcium phosphate (NACP) and antibacterial dimethylaminododecyl methacrylate (DMADDM) were synthesized and incorporated into a composite and an adhesive. Occlusal cavities were prepared in the first molars of rats and restored with four types of restoration: Control composite and adhesive; control plus DMADDM; control plus NACP; and control plus both DMADDM and NACP. At 8 or 30 days (d), rat molars were harvested for histological analysis. For inflammatory cell response, regardless of time periods, NACP group and DMADDM+NACP group showed lower scores (better biocompatibility) than control group (p = 0.014 for 8 d, p = 0.018 for 30 d). For tissue disorganization, NACP and DMADDM+NACP had better scores than control (p = 0.027) at 30 d. At 8 d, restorations containing NACP had tertiary dentin thickness (TDT) that was 5-6 fold that of control. At 30 d, restorations containing NACP had TDT that was 4-6 fold that of control. In conclusion, novel antibacterial and remineralizing restorations were tested in rat teeth in vivo for the first time. Composite and adhesive containing NACP and DMADDM exhibited milder pulpal inflammation and much greater tertiary dentin formation, than control adhesive and composite. Therefore, the novel composite and adhesive containing NACP and DMADDM are promising as a new therapeutic restorative system to not only combat oral pathogens and biofilm acids as shown previously, but also facilitate the healing of the dentin-pulp complex. PMID:24583320

  13. "Dignity": A central construct in nursing home staff understandings of quality continence care.

    PubMed

    Ostaszkiewicz, Joan; Tomlinson, Emily; Hutchinson, Alison M

    2018-02-03

    To explore nursing home staff members' beliefs and expectations about what constitutes "quality continence care" for people living in nursing homes. Most nursing home residents require assistance to maintain continence or manage incontinence. Best practice guidelines promote active investigation of incontinence, treatment of underlying potentially reversible causes, and initial conservative interventions to prevent, minimise and/or treat incontinence. Despite research showing the positive benefits of implementing active interventions, translating the findings of research into practice in nursing homes has been modest. Understanding the perspectives of individuals who provide continence care may help bridge the gap between evidence and practice. A qualitative exploratory descriptive design. Qualitative interviews were conducted with 19 nursing home staff: eight registered nurses, four enrolled nurses and seven personal care workers working in a nursing home in Australia between 2014-2015. Data were analysed inductively to identify themes and subthemes that described and explained staff beliefs about quality continence care in nursing homes. Participants' understanding and expectations about quality continence care were linked to beliefs about incontinence being an intractable and undignified condition in nursing homes. The key theme to emerge was "protecting residents' dignity" which was supported by the following six subthemes: (i) using pads, ii) providing privacy, (iii) knowing how to "manage" incontinence, (iv) providing timely continence care, (v) considering residents' continence care preferences and (vi) communicating sensitively. The findings provide new insight into the basis for continence care practices in nursing homes. Education about continence care should challenge beliefs that limit continence care practice to cleaning, containing and concealing incontinence. There is a need for a multidimensional framework that is informed by social, psychological

  14. Multiple sclerosis and continence issues: an exploratory study.

    PubMed

    Wollin, Judy; Bennie, Mary; Leech, Christine; Windsor, Carol; Spencer, Nancy

    The study described in this article aimed to identify issues relating to incontinence and assess the impact of referral to a continence adviser on the lives of people with multiple sclerosis (MS). The study design used an in-depth, two-phase anonymous mail survey within a general community as nominated by the participants. Fifty-six people participated in phase 1 and eleven people completed phase 2. The results indicated that incontinence is a problem for the vast majority of participants--people with MS. One-third of the eligible participants took up the option of a consultation, assessment and treatment from a continence nurse. Reasons for not taking up the visit from the continence nurse included 'managing OK', 'didn't think it would help', 'embarrassed' and 'too busy'. Increasing awareness of urinary incontinence in the community is important and education needs to focus on at-risk groups in presenting the range of options available to assist people experiencing incontinence.

  15. A unified model of avian species richness on islands and continents.

    PubMed

    Kalmar, Attila; Currie, David J

    2007-05-01

    How many species in a given taxon should be found in a delimited area in a specified place in the world? Some recent literature suggests that the answer to this question depends strongly on the geographical, evolutionary, and ecological context. For example, current theory suggests that species accumulate as a function of area differently on continents and islands. Species richness-climate relationships have been examined separately on continents and on islands. This study tests the hypotheses that (1) the functional relationship between richness and climate is the same on continents and islands; (2) the species-area slope depends on distance-based isolation; (3) species-area relationships differ among land bridge islands, oceanic islands, and continents; (4) richness differs among biogeographic regions independently of climate and isolation. We related bird species numbers in a worldwide sample of 240 continental parcels and 346 islands to several environmental variables. We found that breeding bird richness varies similarly on islands and on continents as a function of mean annual temperature, an area x precipitation interaction, and the distance separating insular samples from the nearest continent (R2 = 0.86). Most studies to date have postulated that the slope of the species-area relationship depends upon isolation. In contrast, we found no such interaction. A richness-environment relationship derived using Old World sites accurately predicts patterns of richness in the New World and vice versa (R2 = 0.85). Our results suggest that most of the global variation in richness is not strongly context-specific; rather, it reflects a small number of general environmental constraints operating on both continents and islands.

  16. A proposed protocol for acceptance and constancy control of computed tomography systems: a Nordic Association for Clinical Physics (NACP) work group report.

    PubMed

    Kuttner, Samuel; Bujila, Robert; Kortesniemi, Mika; Andersson, Henrik; Kull, Love; Østerås, Bjørn Helge; Thygesen, Jesper; Tarp, Ivanka Sojat

    2013-03-01

    Quality assurance (QA) of computed tomography (CT) systems is one of the routine tasks for medical physicists in the Nordic countries. However, standardized QA protocols do not yet exist and the QA methods, as well as the applied tolerance levels, vary in scope and extent at different hospitals. To propose a standardized protocol for acceptance and constancy testing of CT scanners in the Nordic Region. Following a Nordic Association for Clinical Physics (NACP) initiative, a group of medical physicists, with representatives from four Nordic countries, was formed. Based on international literature and practical experience within the group, a comprehensive standardized test protocol was developed. The proposed protocol includes tests related to the mechanical functionality, X-ray tube, detector, and image quality for CT scanners. For each test, recommendations regarding the purpose, equipment needed, an outline of the test method, the measured parameter, tolerance levels, and the testing frequency are stated. In addition, a number of optional tests are briefly discussed that may provide further information about the CT system. Based on international references and medical physicists' practical experiences, a comprehensive QA protocol for CT systems is proposed, including both acceptance and constancy tests. The protocol may serve as a reference for medical physicists in the Nordic countries.

  17. The Malone antegrade continence enema for neurogenic and structural fecal incontinence and constipation.

    PubMed

    Koyle, M A; Kaji, D M; Duque, M; Wild, J; Galansky, S H

    1995-08-01

    Problems of fecal elimination are commonly encountered by the pediatric urologist and surgeon. The Malone antegrade continence enema has been described as a means to administer a large volume enema via a continent catheterizable appendicocecostomy, resulting in reliable fecal elimination. Of 22 patients undergoing this procedure 16 reported total continence 4 months or longer after surgery. Complications are relatively minor and tap water appears to be a safe solution for the antegrade continence enema. A nonrefluxing, imbricated appendicocecostomy is preferable to prevent cutaneous fecal or gas leaks.

  18. Moisture Budget of the MJO over the Maritime Continent

    NASA Astrophysics Data System (ADS)

    Kim, J. E.; Zhang, C.; Kiladis, G. N.; Bechtold, P.

    2017-12-01

    The Maritime Continent (MC) often acts as a barrier for the eastward propagation of the MJO originating from the Indian Ocean (IO). Convective anomalies associated with the MJO tend to weaken over the MC, and MJO convection sometimes fails to pass through the MC. MJO events observed during the DYNAMO field campaign during late 2011 to early 2012 are not an exception in this regard. Modulation of convection for DYNAMO MJOs over the MC is investigated using moisture budget analysis of a reforecast product by the ECMWF Integrated Forecasting System (IFS). Vertical profiles of diabatic drying and heating by physical processes from convection, microphysics, and radiation schemes in IFS under the weak temperature gradient (WTG) environment enable us to estimate vertically resolved processes that control local moistening and drying associated with the MJO. We will compare three-dimensional moisture budgets over the IO and MC to understand which processes contribute to the changes in the MJO propagation and intensity over the MC.

  19. Effect of amorphous calcium phosphate and silver nanocomposites on dental plaque microcosm biofilms.

    PubMed

    Cheng, Lei; Weir, Michael D; Xu, Hockin H K; Antonucci, Joseph M; Lin, Nancy J; Lin-Gibson, Sheng; Xu, Sarah M; Zhou, Xuedong

    2012-07-01

    A dental composite containing amorphous calcium phosphate nanoparticles (NACP) was developed that released calcium (Ca) and phosphate (PO(4)) ions and possessed acid-neutralization capability. There has been little study on incorporation of antibacterial agents into calcium phosphate composites. The objective of this study was to investigate the effect of silver nanoparticle (NAg) mass fraction in NACP nanocomposite on mechanical properties and dental plaque microcosm biofilm for the first time. NACP nanoparticles of 116 nm were synthesized via a spray-drying technique. NAg nanoparticles were synthesized using Ag 2-ethylhexanoate and 2-(tert-butylamino)ethyl methacrylate, yielding NAg of particle size of 2.7 nm that were well-dispersed in the resin. Five NACP nanocomposites were fabricated with NAg mass fractions of 0, 0.028, 0.042, 0.088, and 0.175%, respectively. Mechanical properties of NACP nanocomposites containing 0-0.042% of NAg matched those of a commercial composite without antibacterial activity. Live/dead assay of dental plaque microcosm biofilms showed complete coverage with live bacteria on commercial composite. However, there were increasingly more dead bacteria with higher NAg content in the NACP nanocomposite. Colony-forming unit (CFU) counts for total microorganisms, total streptococci, and mutans streptococci for NACP nanocomposite with 0.042% NAg were about 1/4 those of commercial composite. Lactic acid production on NACP nanocomposite with 0.042% NAg was 1/3 that on commercial composite. In conclusion, novel NACP-NAg nanocomposites were developed which possessed good mechanical properties and potent antibacterial properties, with substantially reduced biofilm viability and lactic acid production. Hence, the NACP-NAg nanocomposites are promising for dental restorations with remineralizing and antibacterial capabilities. Copyright © 2012 Wiley Periodicals, Inc.

  20. How the growth and freeboard of continents may relate to geometric and kinematic parameters of mid-ocean spreading ridges

    USGS Publications Warehouse

    Howell, D.G.

    1989-01-01

    If the volume of continents has been growing since 4 Ga then the area of the ocean basins must have been shrinking. Therefore, by inferring a constant continental freeboard, in addition to constant continental crustal thicknesses and seawater volume, it is possible to calculate the necessary combinations of increased ridge lengths and spreading rates required to displace the seawater in the larger oceans of the past in order to maintain the constant freeboard. A reasonable choice from the various possibilities is that at 4 Ga ago, the ridge length and spreading rates were ca. 2.5 times greater than the averages of these parameters during the past 200 Ma. By 2.5 Ga ago the ridge length and spreading rate decreased to about 1.8 times the recent average and by 1 Ga ago these features became reduced to approximately 1.4 times recent averages. ?? 1989.

  1. Dynamical origin of near- and below-threshold harmonic generation of Cs in an intense mid-infrared laser field.

    PubMed

    Li, Peng-Cheng; Sheu, Yae-Lin; Laughlin, Cecil; Chu, Shih-I

    2015-05-20

    Near- and below-threshold harmonic generation provides a potential approach to generate vacuum-ultraviolet frequency comb. However, the dynamical origin of in these lower harmonics is less understood and largely unexplored. Here we perform an ab initio quantum study of the near- and below-threshold harmonic generation of caesium (Cs) atoms in an intense 3,600-nm mid-infrared laser field. Combining with a synchrosqueezing transform of the quantum time-frequency spectrum and an extended semiclassical analysis, the roles of multiphoton and multiple rescattering trajectories on the near- and below-threshold harmonic generation processes are clarified. We find that the multiphoton-dominated trajectories only involve the electrons scattered off the higher part of the combined atom-field potential followed by the absorption of many photons in near- and below-threshold regime. Furthermore, only the near-resonant below-threshold harmonic is exclusive to exhibit phase locked features. Our results shed light on the dynamic origin of the near- and below-threshold harmonic generation.

  2. Impact of a continence training program on patient safety and quality.

    PubMed

    Grandstaff, Marcia; Lyons, Deborah

    2012-01-01

    The purpose of this study is to examine the impact of an evidence-based training program on patient outcomes of continence, falls, and discharge disposition in the rehab population. Criteria for inclusion required new onset of two or more episodes of urinary incontinence. Sixty-six subjects were enrolled with 33 subjects receiving evidence-based interventions. The intervention group showed improvement in continence (p = .020), with no difference between groups on discharge disposition (p = .744). Results showed an unexpected higher occurrence of falls in the treatment group (p = .000). DISCUSSION AND CLINICAL RELEVANCE: This study supports existing literature indicating that continence is not an independent predictor of nursing home admission and offers new evidence that use of an evidence-based intervention bundle can significantly improve patient continence including those patients with mild to moderate cognitive impairment. © 2012 Association of Rehabilitation Nurses.

  3. Failed pelvic pouch substituted by continent ileostomy.

    PubMed

    Wasmuth, H H; Tranø, G; Wibe, A; Endreseth, B H; Rydning, A; Myrvold, H E

    2010-07-01

    The long-term failure rate of ileal pouch-anal anastomosis (IPAA) is 10-15%. When salvage surgery is unsuccessful, most surgeons prefer pouch excision with conventional ileostomy, thus sacrificing 40-50 cm of ileum. Conversion of a pelvic pouch to a continent ileostomy (CI, Kock pouch) is an alternative that preserves both the ileal surface and pouch properties. The aim of the study was to evaluate clinical outcome after the construction of a CI following a failed IPAA. During 1984-2007, 317 patients were operated with IPAA at St Olavs Hospital and evaluated for failure, treatment and outcome. Seven patients with IPAA failure had CI. Four patients with IPAA failure referred from other hospitals underwent conversion to CI and are included in the final analysis. Seven patients had a CI constructed from the transposing pelvic pouch and four had the pelvic pouch removed and a new continent pouch constructed from the distal ileum. Median follow up after conversion to CI was 7 years (0-17 years). Two CI had to be removed due to fistulae. One patient needed a revision of the nipple valve due to pouch loosening. At the end of follow-up, 8 of the 11 patients were fully continent. One patient with Crohn's disease had minor leakage. In patients with pelvic pouch failure, the possibility of conversion to CI should be presented to the patient as an alternative to pouch excision and permanent ileostomy. The advantage is the continence and possibly a better body image. Construction of a CI on a new ileal segment may be considered, but the consequences of additional small bowel loss and risk of malnutrition if the Kock pouch fails should be appraised.

  4. The thermal influence of continents on a model-generated January climate

    NASA Technical Reports Server (NTRS)

    Spar, J.; Cohen, C.; Wu, P.

    1981-01-01

    Two climate simulations were compared. Both climate computations were initialized with the same horizontally uniform state of rest. However, one is carried out on a water planet (without continents), while the second is repeated on a planet with geographically realistic but flat (sea level) continents. The continents in this experiment have a uniform albedo of 0.14, except where snow accumulates, a uniform roughness height of 0.3 m, and zero water storage capacity. Both runs were carried out for a 'perpetual January' with solar declination fixed at January 15.

  5. Impact of abuse-deterrent OxyContin on prescription opioid utilization.

    PubMed

    Hwang, Catherine S; Chang, Hsien-Yen; Alexander, G Caleb

    2015-02-01

    We quantified the degree to which the August 2010 reformulation of abuse-deterrent OxyContin affected its use, as well as the use of alternative extended-release and immediate-release opioids. We used the IMS Health National Prescription Audit, a nationally representative source of prescription activity in the USA, to conduct a segmented time-series analysis of the use of OxyContin and other prescription opioids. Our primary time period of interest was 12 months prior to and following August 2010. We performed model checks and sensitivity analyses, such as adjusting for marketing and promotion, using alternative lag periods, and adding extra observation points. OxyContin sales were similar before and after the August 2010 reformulation, with approximately 550 000 monthly prescriptions. After adjusting for declines in the generic extended-release oxycodone market, the formulation change was associated with a reduction of approximately 18 000 OxyContin prescription sales per month (p = 0.02). This decline corresponded to a change in the annual growth rate of OxyContin use, from 4.9% prior to the reformulation to -23.8% during the year after the reformulation. There were no statistically significant changes associated with the sales of alternative extended-release (p = 0.42) or immediate-release (p = 0.70) opioids. Multiple sensitivity analyses supported these findings and their substantive interpretation. The market debut of abuse-deterrent OxyContin was associated with declines in its use after accounting for the simultaneous contraction of the generic extended-release oxycodone market. Further scrutiny into the effect of abuse-deterrent formulations on medication use and health outcomes is vital given their popularity in opioid drug development. Copyright © 2014 John Wiley & Sons, Ltd.

  6. Louisiana mid-cycle survey shows change in forests resource trends

    Treesearch

    Charles E. Thomas; Carl V. Bylin

    1982-01-01

    Because costs of doing surveys are escalating rapidly, and both dollars and manpower are scarce resources, a low-intensity survey for the mid-cycle inventory may be the answer to timely monitoring of state resource trends.

  7. Excisional hemorrhoidal surgery and its effect on anal continence

    PubMed Central

    Li, Yan-Dong; Xu, Jia-He; Lin, Jian-Jiang; Zhu, Wei-Fang

    2012-01-01

    AIM: To investigate the role of anal cushions in hemorrhoidectomy and its effect on anal continence of the patients. METHODS: Seventy-six consecutive patients (33 men and 43 women) with a mean age of 44 years were included. They underwent Milligan-Morgan hemorrhoidectomy because of symptomatic third- and fourth-degree hemorrhoids and failure in conservative treatment for years. Wexner score was recorded and liquid continence test was performed for each patient before and two months after operation using the techniques described in our previous work. The speed-constant rectal lavage apparatus was prepared in our laboratory. The device could output a pulsed and speed-constant saline stream with a high pressure, which is capable of overcoming any rectal resistance change. The patients were divided into three groups, group A (< 900 mL), group B (900-1200 mL) and group C (> 1200 mL) according to the results of the preoperative liquid continence test. RESULTS: All the patients completed the study. The average number of hemorrhoidal masses excised was 2.4. Most patients presented with hemorrhoidal symptoms for more than one year, including a mean duration of incontinence of 5.2 years. The most common symptoms before surgery were anal bleeding (n = 55), prolapsed lesion (n = 34), anal pain (n = 12) and constipation (n = 17). There were grade III hemorrhoids in 39 (51.3%) patients, and grade IV in 37 (48.7%) patients according to Goligher classification. Five patients had experienced hemorrhoid surgery at least once. Compared with postoperative results, the retained volume in the preoperative liquid continence test was higher in 40 patients, lower in 27 patients, and similar in the other 9 patients. The overall preoperative retained volume in the liquid continence test was 1130.61 ± 78.35 mL, and postoperative volume was slightly decreased (991.27 ± 42.77 mL), but there was no significant difference (P = 0.057). Difference was significant in the test value before and

  8. Novel calcium phosphate nanocomposite with caries-inhibition in a human in situ model

    PubMed Central

    Melo, Mary Anne S.; Weir, Michael D.; Rodrigues, Lidiany K.A.; Xu, Hockin H.K.

    2013-01-01

    Objectives Secondary caries at the restoration margins remains the main reason for failure. Although calcium phosphate (CaP) composites are promising for caries inhibition, there has been no report of CaP composite to inhibit caries in situ. The objectives of this study were to investigate the caries-inhibition effect of nanocomposite containing nanoparticles of amorphous calcium phosphate (NACP) in a human in situ model for the first time, and to determine colony-forming units (CFU) and Ca and P ion concentrations of biofilms on the composite restorations. Methods NACP with a mean particle size of 116 nm were synthesized via a spray-drying technique. Two composites were fabricated: NACP nanocomposite, and control composite filled with glass particles. Twenty-five volunteers wore palatal devices containing bovine enamel slabs with cavities restored with NACP or control composite. After 14 days, the adherent biofilms were collected for analyses. Transverse microradiography determined the enamel mineral profiles at the margins, and the enamel mineral loss ! Z was measured. Results NACP nanocomposite released Ca and P ions and the release significantly increased at cariogenic low pH (p < 0.05). Biofilms on NACP nanocomposite contained higher Ca (p = 0.007) and P ions (p = 0.005) than those of control (n = 25). There was no significant difference in biofilm CFU between the two composites (p > 0.1). Microradiographs showed typical subsurface lesions in enamel next to control composite, but much less lesion around NACP nanocomposite. Enamel mineral loss ! Z (mean ± sd; n = 25) around NACP nanocomposite was 13.8 ± 9.3 μm, much less than 33.5 ± 19.0 μm of the control (p = 0.001). Significance Novel NACP nanocomposite substantially reduced caries formation in a human in situ model for the first time. Enamel mineral loss at the margins around NACP nanocomposite was less than half of the mineral loss around control composite. Therefore, the Ca and P ion-releasing NACP

  9. Long-term dentin remineralization by poly(amido amine) and rechargeable calcium phosphate nanocomposite after fluid challenges.

    PubMed

    Liang, Kunneng; Xiao, Shimeng; Wu, Junling; Li, Jiyao; Weir, Michael D; Cheng, Lei; Reynolds, Mark A; Zhou, Xuedong; Xu, Hockin H K

    2018-04-01

    Previous studies investigated short-term dentin remineralization; studies on long-term dentin remineralization after fluid challenges mimicking fluids in oral environment are lacking. The objective of this study was to develop a long-term remineralization method to via poly(amido amine) (PAMAM) and rechargeable composite containing nanoparticles of amorphous calcium phosphate (NACP) after fluid challenges for the first time. NACP composite was immersed at pH 4 to exhaust its calcium (Ca) and phosphate (P) ions, and then recharged with Ca and P ions, to test the remineralization of the exhausted and recharged NACP composite. Dentin was acid-etched with 37% phosphoric acid. Four groups were prepared: (1) dentin control, (2) dentin with PAMAM, (3) dentin with the recharged NACP composite, and (4) dentin with PAMAM plus recharged NACP composite. PAMAM-coated dentin was immersed in phosphate-buffered saline with shaking for 72 days, because there is fluid flow in the mouth which could potentially detach the PAMAM from dentin. Specimens were treated with a cyclic artificial saliva/lactic acid regimen for 35 days. After 72days of immersion plus shaking, the PAMAM still successfully fulfilled its mineralization nucleation. The recharged NACP composite still provided acid-neutralization and ion re-release, which did not decrease with increasing the number of recharge cycles. The immersed-PAMAM plus NACP achieved complete dentin remineralization and restored the hardness to that of healthy dentin. In conclusion, superior long-term remineralization of the PAMAM plus NACP method was demonstrated for the first time. The immersed-PAMAM plus recharged NACP completely remineralized the pre-demineralized dentin, even after prolonged fluid-challenge similar to that in oral environment. The novel PAMAM plus NACP composite method is promising to provide long-term tooth protection and caries inhibition. Copyright © 2018 The Academy of Dental Materials. Published by Elsevier Ltd. All

  10. Effects of Midrotation Intensive Silviculture on Forest Soils in East Texas: First-Year Results

    Treesearch

    S.A. Wilson; K.W. Farrish; B.P. Oswald; H.M. Williams; J.L. Yeiser

    2002-01-01

    Intensive forest management is becoming increasingly common in east Texas.Included in intensive management are such practices as mid-rotation fertilization, prescribed fire, and herbicide application. There is insufficient information about the effects of these treatments on soil physical, chemical, and biological properties when applied at mid-rotation. The objectives...

  11. Differential effects of cough, valsalva, and continence status on vesical neck movement.

    PubMed

    Howard, D; Miller, J M; Delancey, J O; Ashton-Miller, J A

    2000-04-01

    We tested the null hypothesis that vesical neck descent is the same during a cough and during a Valsalva maneuver. We also tested the secondary null hypothesis that differences in vesical neck mobility would be independent of parity and continence status. Three groups were included: 17 nulliparous continent (31.3 +/- 5.6; range 22-42 years), 18 primiparous continent (30.4 +/- 4.3; 24-43), and 23 primiparous stress-incontinent (31.9 +/- 3.9; 25-38) women. Measures of vesical neck position at rest and during displacement were obtained by ultrasound. Abdominal pressures were recorded simultaneously using an intravaginal microtransducer catheter. To control for differing abdominal pressures, the stiffness of the vesical neck support was calculated by dividing the pressure exerted during a particular effort by the urethral descent during that effort. The primiparous stress-incontinent women displayed similar vesical neck mobility during a cough effort and during a Valsalva maneuver (13.8 mm compared with 14.8 mm; P =.49). The nulliparous continent women (8.2 mm compared with 12.4 mm; P =. 001) and the primiparous continent women (9.9 mm compared with 14.5 mm; P =.002) displayed less mobility during a cough than during a Valsalva maneuver despite greater abdominal pressure during cough. The nulliparas displayed greater pelvic floor stiffness during a cough compared with the continent and incontinent primiparas (22.7, 15.5, 12.2 cm H(2)O/mm, respectively; P =.001). There are quantifiable differences in vesical neck mobility during a cough and Valsalva maneuver in continent women. This difference is lost in the primiparous stress-incontinent women.

  12. Anisotropic tomography of the Indian continent and the geodynamic role of its keel

    NASA Astrophysics Data System (ADS)

    Montagner, J. P.; Maurya, S.; Sibrant, A.; Davaille, A.; Stutzmann, E.; Kumar, R.; Jean, B.

    2017-12-01

    The Indian moved at an exceptional high rate (18-20cm/year) after the birth of La Réunion hotspot, ≈65Ma ago and the Deccan volcanic province before the collision with the Asian continent. Other older plumes Marion, Kerguelen located in the Indian ocean are also associated with very fast plate motion. We present a high-resolution 3D anisotropic model of the Indian plate region down to 300 km depth, obtained by inverting a new massive database of surface-wave observations. The Rayleigh and Love wave dispersion measurements along 14,000 paths are made in a broad frequency range (16-250s). Our estimates of the depth to the Lithosphere-Asthenosphere Boundary (LAB) derived from seismic velocity Vsv variations at depth reveal large variations (120-250 km) beneath the different cratonic blocks. A low velocity layer associated with the Mid-lithospheric discontinuity is present when the root of the lithosphere is deep. This extensive anisotropic tomographic investigation of the Indian continent displays an almost north-south keel, 600km long and 300km wide, down to 250km depth. The keel is characterized by fast velocities, smaller than average radial and azimuthal anisotropies. The distribution of azimuthal anisotropy defines the flow lines around the keel, and, at the LAB, coincides with the APM direction of the Indian plate. The fast axis azimuths at 250 km depth are also in accordance with the results from SK(K)S splitting. Such a keel could probably perturb plume-induced flow in the asthenosphere. To determine the influence of such a keel on the interaction of India with several mantle plumes (Marion, Crozet, Kerguelen, La Réunion), we used laboratory experiments. Some preliminary results will be presented on the comparison between the laboratory flowlines and the direction of seismic anisotropy.

  13. Tectonic evolution and extension at the Møre Margin - Offshore mid-Norway

    NASA Astrophysics Data System (ADS)

    Theissen-Krah, S.; Zastrozhnov, D.; Abdelmalak, M. M.; Schmid, D. W.; Faleide, J. I.; Gernigon, L.

    2017-11-01

    Lithospheric stretching is the key process in forming extensional sedimentary basins at passive rifted margins. This study explores the stretching factors, resulting extension, and structural evolution of the Møre segment on the Mid-Norwegian continental margin. Based on the interpretation of new and reprocessed high-quality seismic, we present updated structural maps of the Møre margin that show very thick post-rift sediments in the central Møre Basin and extensive sill intrusion into the Cretaceous sediments. A major shift in subsidence and deposition occurred during mid-Cretaceous. One transect across the Møre continental margin from the Slørebotn Subbasin to the continent-ocean boundary is reconstructed using the basin modelling software TecMod. We test different initial crustal configurations and rifting events and compare our structural reconstruction results to stretching factors derived both from crustal thinning and the classical backstripping/decompaction approach. Seismic interpretation in combination with structural reconstruction modelling does not support the lower crustal bodies as exhumed and serpentinised mantle. Our extension estimate along this transect is 188 ± 28 km for initial crustal thickness varying between 30 and 40 km.

  14. Early- to Mid-Holocene hydroclimate shifts in tropical East Africa: the multi-proxy sediment record from Lake Rutundu, Kenya

    NASA Astrophysics Data System (ADS)

    De Cort, Gijs; Creutz, Mike; Barao, Lucia; Conley, Daniel; Haug, Gerald; Bodé, Samuel; Blaauw, Maarten; Engstrom, Dan; Verschuren, Dirk

    2015-04-01

    Following the generally arid conditions of the Last Glacial Maximum (LGM), a large part of the African continent experienced the Early to Mid-Holocene as a much more humid period than today. This so-called African Humid Period (AHP) coincided with high summertime insolation over the Northern Hemisphere subtropics, causing invigorated monsoons to create moist conditions over the northern parts of the continent. Similarly, equatorial and even low-latitude southeastern Africa experienced a wetter climate due to the post-glacial increase in atmospheric greenhouse gasses ultimately leading to altered Atlantic and Indian Ocean monsoon dynamics. The timing and abruptness of the onset and ending of the AHP in the different regions of the continent have been the subject of major discussion. On the other hand, shorter-lived climate fluctuations within the AHP have received much less attention, due to a scarcity of well-dated, high-resolution African paleoclimate records spanning the entire Holocene. In this study we used the sediment record of Lake Rutundu, a high-altitude crater lake on Mount Kenya, to document multidecadal to millennial-scale hydroclimate variability on the East African equator from the LGM to the present. A multiproxy approach combining core-surface scanning techniques (magnetic susceptibility, X-ray fluorescence) and close-interval bulk-sediment analyses (organic matter and biogenic Si content, grain size, organic δ15N and δ13C) resulted in a high-resolution record firmly anchored in time by an age model based on 210Pb dating and sixteen calibrated radiocarbon ages. This new Lake Rutundu hydroclimate record confirms that moister conditions following the LGM returned to East Africa ca.16 kyr BP, and it contains a perfectly timed Younger Dryas episode (12.8-11.5 kyr BP) of intermittent drought. We find that the Early- to Mid-Holocene period, which in African records is often described as uniformly wet, was in fact punctuated by three distinct, century

  15. Colon pouch (Mainz III) for continent urinary diversion.

    PubMed

    Stolzenburg, Jens-Uwe; Schwalenberg, Thilo; Liatsikos, Evangelos N; Sakelaropoulos, George; Rödder, Kilian; Hohenfellner, Rudolph; Fisch, Margit

    2007-06-01

    To evaluate the use of a continent cutaneous pouch made exclusively of colon (Mainz pouch III), as excellent results with the Mainz pouch III in irradiated patients suggested that the indication for this type of urinary diversion could be extended. The outcome of 24 patients with continent cutaneous urinary diversions using colon segments (Mainz pouch III) was investigated retrospectively. Overall, 22 of the patients had a malignant disease and two a benign disease; 16 had a hysterectomy and pelvic exenteration for gynaecological tumours; two men with a rhabdomyosarcoma of the prostate had a radical cystoprostatectomy; one woman had pelvic exenteration for bladder cancer; one man had a simultaneous rectum resection due to infiltrating rectal cancer, and another a left nephrectomy with cystectomy for concomitant kidney and bladder tumour. Benign indications were hyper-reflexive bladder after polytrauma and two cases of neurogenic bladder dysfunction. Eighteen patients had radiotherapy (32-48 Gy) before the urinary diversion. The mean (range) follow-up was 35 (12-65) months. The mean pouch capacity was 293.8 mL. Three patients died during the follow-up (two from disease progression and one suicide); 20 patients were fully continent, four with reduced pouch capacity (<300 mL) had slight incontinence and are wearing a protective pad (band-aid at the umbilicus). All patients use intermittent self-catheterization (mean catheterization frequency 6.8/day, range 6-12). Complications related to the pouch were one outlet stenosis that required revision. Postoperative pouchograms showed asymptomatic reflux in four patients. None of the patients developed metabolic acidosis or diarrhoea. The Mainz pouch III is an alternative to other types of continent urinary diversion.

  16. Do nurses promote urinary continence in hospitalized older people?: An exploratory study.

    PubMed

    Dingwall, Lindsay; McLafferty, Ella

    2006-10-01

    The aim of this paper is to explore whether nurses working in elderly medicine and in acute medical settings promote urinary continence in older people or in reality use containment strategies. Untreated urinary incontinence in older adults can result in prolonged hospital admission and increased risk of admission to long-term care. Urinary incontinence can also have severe psychosocial effects on older people. Most studies relating to this topic have relied on quantitative approaches to data collection with a seeming lack of qualitative investigation into how nursing staff promote urinary continence in hospitalized older people. Focus groups and one-to-one semi-structured interviews were carried out in two NHS regions in Scotland. Registered and non-Registered Nurses were invited to participate. Five focus groups (n = 17) and four single interviews (n = 4) were conducted. Data generated were analysed thematically using QSR N-VIVO 2. Some nurses believe that older people accept urinary incontinence as a consequence of ageing. Lack of assessment results in older people being labelled as incontinent of urine. Assessment strategies in medicine for the elderly tend to focus on product identification and management of incontinence. Although nurses from all clinical areas identify the importance of promoting continence, the problem continues to be contained rather than treated. Conflicting clinical priorities, varying staff approaches to urinary continence and deficits in education are cited among the barriers to promoting continence. The results suggest that nurses continue to contain urinary incontinence rather than promoting continence in older people. Nursing staff need to be aware of the impact of untreated urinary incontinence on older people. Practitioners should promote continence rather than employing containment strategies. A validated assessment tool for older people needs to be developed. Views of older people should be sought regarding their attitudes

  17. Preoperative predictive model of recovery of urinary continence after radical prostatectomy.

    PubMed

    Matsushita, Kazuhito; Kent, Matthew T; Vickers, Andrew J; von Bodman, Christian; Bernstein, Melanie; Touijer, Karim A; Coleman, Jonathan A; Laudone, Vincent T; Scardino, Peter T; Eastham, James A; Akin, Oguz; Sandhu, Jaspreet S

    2015-10-01

    To build a predictive model of urinary continence recovery after radical prostatectomy (RP) that incorporates magnetic resonance imaging (MRI) parameters and clinical data. We conducted a retrospective review of data from 2,849 patients who underwent pelvic staging MRI before RP from November 2001 to June 2010. We used logistic regression to evaluate the association between each MRI variable and continence at 6 or 12 months, adjusting for age, body mass index (BMI) and American Society of Anesthesiologists (ASA) score, and then used multivariable logistic regression to create our model. A nomogram was constructed using the multivariable logistic regression models. In all, 68% (1,742/2,559) and 82% (2,205/2,689) regained function at 6 and 12 months, respectively. In the base model, age, BMI and ASA score were significant predictors of continence at 6 or 12 months on univariate analysis (P < 0.005). Among the preoperative MRI measurements, membranous urethral length, which showed great significance, was incorporated into the base model to create the full model. For continence recovery at 6 months, the addition of membranous urethral length increased the area under the curve (AUC) to 0.664 for the validation set, an increase of 0.064 over the base model. For continence recovery at 12 months, the AUC was 0.674, an increase of 0.085 over the base model. Using our model, the likelihood of continence recovery increases with membranous urethral length and decreases with age, BMI and ASA score. This model could be used for patient counselling and for the identification of patients at high risk for urinary incontinence in whom to study changes in operative technique that improve urinary function after RP. © 2015 The Authors BJU International © 2015 BJU International Published by John Wiley & Sons Ltd.

  18. The Impact on Career Direction of a Tertiary Management Programme for Mid-Career ICT Professionals

    ERIC Educational Resources Information Center

    Hooper, Tony

    2009-01-01

    The motivation of mid-career students can be expected to be more considered and intense than students whose studies continue from undergraduate programmes. How students perceive their personal circumstances and their career when they first make the decision to enrol and what happens as a result of their studies can reveal how mid-career management…

  19. Impact of posterior rhabdosphincter reconstruction during robot-assisted radical prostatectomy: retrospective analysis of time to continence.

    PubMed

    Woo, Jason R; Shikanov, Sergey; Zorn, Kevin C; Shalhav, Arieh L; Zagaja, Gregory P

    2009-12-01

    Posterior rhabdosphincter (PR) reconstruction during robot-assisted radical prostatectomy (RARP) was introduced in an attempt to improve postoperative continence. In the present study, we evaluate time to achieve continence in patients who are undergoing RARP with and without PR reconstruction. A prospective RARP database was searched for most recent cases that were accomplished with PR reconstruction (group 1, n = 69) or with standard technique (group 2, n = 63). We performed the analysis applying two definitions of continence: 0 pads per day or 0-1 security pad per day. Patients were evaluated by telephone interview. Statistical analysis was carried out using the Kaplan-Meier method and log-rank test. With PR reconstruction, continence was improved when defined as 0-1 security pad per day (median time of 90 vs 150 days; P = 0.01). This difference did not achieve statistical significance when continence was defined as 0 pads per day (P = 0.12). A statistically significant improvement in continence rate and time to achieve continence is seen in patients who are undergoing PR reconstruction during RARP, with continence defined as 0-1 security/safety pad per day. A larger, prospective and randomized study is needed to better understand the impact of this technique on postoperative continence.

  20. Continence outcomes in patients undergoing robotic assisted laparoscopic mitrofanoff appendicovesicostomy.

    PubMed

    Wille, Mark A; Zagaja, Gregory P; Shalhav, Arieh L; Gundeti, Mohan S

    2011-04-01

    Continent catheterizable channels for emptying the bladder are typically performed via an open surgical approach. We present our surgical approach and initial outcomes with specific attention to continence for robotic assisted laparoscopic Mitrofanoff appendicovesicostomy formation. Between February 2008 and April 2010, 13 patients were considered for robotic assisted laparoscopic Mitrofanoff appendicovesicostomy and 11 underwent the procedure (2 open conversions). Five patients underwent enterocystoplasty with appendicovesicostomy and 6 underwent isolated appendicovesicostomy. The appendicovesicostomy anastomosis was performed on the anterior (without augmentation) or posterior (with augmentation) bladder wall and the stoma was brought to the umbilical site or right lower quadrant. Detrusor backing (4 cm) was ensured except in 1 patient (number 5). Mean patient age at surgery was 10.4 years (range 5 to 14). Mean estimated blood loss was 61.8 cc. Mean operative time for isolated appendicovesicostomy was 347 minutes and there were no intraoperative complications. Incontinence through the stoma developed in 1 patient with inadequate detrusor backing (less than 4 cm), which resolved with dextranomer/hyaluronic acid injection into the appendicovesicostomy anastomosis. This patient had resolution of incontinence with an increase in bladder capacity to 300 cc. Three patients required skin flap revision for cutaneous scarring. To date all patients are catheterizing without difficulty and are continent. Median followup was 20 months (range 3 to 29). We are encouraged by our preliminary experience with the robotic assisted laparoscopic Mitrofanoff appendicovesicostomy continent urinary diversion with or without ileocystoplasty. Early in the experience we emphasize the importance of 4 cm of detrusor backing to maintain stomal continence. Copyright © 2011 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  1. The urethral pressure profiles in continent and stress-incontinent women.

    PubMed

    Henriksson, L; Andersson, K E; Ulmsten, U

    1979-01-01

    Simultaneous urethrocystometry, including recording of the urethral pressure profile, was performed in 127 women aged 30 to 69 years; 42 of the women were free from urologic disorders and 85 had stress incontinence of urine. Both groups were subgrouped according to age. The results in the continent and the incontinent women were analyzed separately, in order to disclose any age-related changes. The data within each decade of age were also comparatively analyzed. In the bladder pressure at rest no age-related changes were found, and the readings were similar in the continent and the incontinent women. The maximum urethral pressure fell significantly with rising age in both groups and was significantly reduced in stress incontinence. The urethral closure pressure showed variations similar to those in the maximum urethral pressure. No lower limit of urethral closure pressure that definitely predisposed to stress incontinence could be established. The functional length of the urethra diminished significantly with rising age in the continent, but not in the incontinent women. The absolute length of the urethra did not show such diminution. Both the functional and the absolute urethral length were significantly less in the incontinent than in the continent women in the age groups between 30 and 49 years.

  2. Dy{sup 3+}-doped Ga–Sb–S chalcogenide glasses for mid-infrared lasers

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Mingjie; Yang, Anping, E-mail: apyang@jsnu.edu.cn; Peng, Yuefeng

    2015-10-15

    Highlights: • Novel Ga–Sb–S chalcogenide glasses doped with Dy{sup 3+} ions were synthesized. • The glasses show good thermal stability and excellent infrared transparency. • The glasses show low phonon energy and intense mid-infrared emissions. • The mid-infrared emissions have high quantum efficiency. • The mid-infrared emissions have large stimulated emission cross sections. - Abstract: Novel Ga–Sb–S chalcogenide glasses doped with different amount of Dy{sup 3+} ions were prepared. Their thermal stability, optical properties, and mid-infrared (MIR) emission properties were investigated. The glasses show good thermal stability, excellent infrared transparency, very low phonon energy (∼306 cm{sup −1}), and intense emissionsmore » centered at 2.95, 3.59, 4.17 and 4.40 μm. Three Judd–Ofelt intensity parameters (Ω{sub 2} = 8.51 × 10{sup −20} cm{sup 2}, Ω{sub 4} = 2.09 × 10{sup −20} cm{sup 2}, and Ω{sub 6} = 1.60 × 10{sup −20} cm{sup 2}) are obtained, and the related radiative transition properties are evaluated. The high quantum efficiencies and large stimulated emission cross sections of the MIR emissions (88.10% and 1.11 × 10{sup −20} cm{sup 2} for 2.95 μm emission, 75.90% and 0.38 × 10{sup −20} cm{sup 2} for 4.40 μm emission, respectively) in the Dy{sup 3+}-doped Ga–Sb–S glasses make them promising gain materials for the MIR lasers.« less

  3. Overactive bladder is a negative predictor of achieving continence after robot-assisted radical prostatectomy.

    PubMed

    Yamada, Yuta; Fujimura, Tetsuya; Fukuhara, Hiroshi; Sugihara, Toru; Miyazaki, Hideyo; Nakagawa, Tohru; Kume, Haruki; Igawa, Yasuhiko; Homma, Yukio

    2017-10-01

    To investigate predictors of continence outcomes after robot-assisted radical prostatectomy. Clinical records of 272 patients who underwent robot-assisted radical prostatectomy were investigated. Preoperative Overactive Bladder Symptom Score, International Prostate Symptom Score and clinicopathological factors were investigated, and relationships between factors and recovery of continence after robot-assisted radical prostatectomy were assessed. The presence of overactive bladder was defined as having urgency for more than once a week and having ≥3 points according to the Overactive Bladder Symptom Score. Age (≤66 years) was significantly associated with continence within 6 months after robot-assisted radical prostatectomy (P = 0.033). The absence of overactive bladder and lower Overactive Bladder Symptom Score (<3) were significantly associated with recovery of continence within 12 months after surgery (both variables P = 0.009). In terms of achieving recovery of continence after robot-assisted radical prostatectomy, Kaplan-Meier curves showed earlier recovery in "age ≤66 years," "prostate weight ≤40 g" and "overactive bladder symptom score <3" (P = 0.0072, 0.0172 and 0.0140, respectively). Multivariate analysis showed that the presence of overactive bladder was an independent negative predictor for recovery of continence within 12 months after surgery (P = 0.019). The presence of baseline overactive bladder seems to represent an independent negative predictor for recovery of continence at 12 months after robot-assisted radical prostatectomy. © 2017 The Japanese Urological Association.

  4. Sonographic evaluation of the bladder neck in continent and stress-incontinent women.

    PubMed

    Schaer, G N; Perucchini, D; Munz, E; Peschers, U; Koechli, O R; Delancey, J O

    1999-03-01

    To evaluate a new sonographic method to measure depth and width of proximal urethral dilation during coughing and Valsalva maneuver and to report its use in a group of stress-incontinent and continent women. Fifty-eight women were evaluated, 30 with and 28 without stress incontinence proven urodynamically, with a bladder volume of 300 mL and the subjects upright. Urethral pressure profiles at rest were performed with a 10 French microtip pressure catheter. Bladder neck dilation and descent were assessed by perineal ultrasound (5 MHz curved linear array transducer) with the help of ultrasound contrast medium (galactose suspension-Echovist-300), whereas abdominal pressure was assessed with an intrarectal balloon catheter. Statistical analysis used the nonparametric Mann-Whitney test. The depth and diameter of urethral dilation could be measured in all women. During Valsalva, all 30 incontinent women exhibited urethral dilation. One incontinent woman showed dilation only while performing a Valsalva maneuver, not during coughing. In the continent group, 12 women presented dilation during Valsalva and six during coughing. In continent women, dilation was visible only in those who were parous. Nulliparous women did not have dilation during Valsalva or coughing. Bladder neck descent was visible in continent and incontinent women. This method permits quantification of depth and diameter of bladder neck dilation, showing that both incontinent and continent women might have bladder neck dilation and that urinary continence can be established at different locations along the urethra in different women. Parity seems to be a main prerequisite for a proximal urethral defect with bladder neck dilation.

  5. Are natural and unnatural appetites equally controllable? A response to Jensen's "Is continence enough?".

    PubMed

    Smith, Janet E

    2004-01-01

    This response challenges Jensen's analysis in no substantial way. Rather, it explains more fully some of the moral character categories that Aristotle provides. It argues that Aristotle understood there to be two forms of continence: the continence that enables us to control natural appetites and"some form"of continence directed towards unnatural appetites, generally engendered by some pathology or abuse.

  6. A possible impact of cooling over the Tibetan Plateau on the mid-Holocene East Asian monsoon climate

    NASA Astrophysics Data System (ADS)

    Jin, Liya; Wang, Huijun; Chen, Fahu; Jiang, Dabang

    2006-12-01

    By using a 9-level global atmospheric general circulation model developed at the Institute of Atmospheric Physics (IAP9L-AGCM) under the Chinese Academy of Sciences, the authors investigated the response of the East Asian monsoon climate to changes both in orbital forcing and the snow and glaciers over the Tibetan Plateau at the mid-Holocene, about 600 calendar years before the present (6 kyr BP). With the Earth’s orbital parameters appropriate for the mid-Holocene, the IAP9L-AGCM computed warmer and wetter conditions in boreal summer than for the present day. Under the precondition of continental snow and glacier cover existing over part of the Tibetan Plateau at the mid-Holocene, the authors examined the regional climate response to the Tibetan Plateau cooling. The simulations indicated that climate changes in South Asia and parts of central Asia as well as in East Asia are sensitive to the Tibetan Plateau cooling at the mid-Holocene, showing a significant decrease in precipitation in northern India, northern China and southern Mongolia and an increase in Southeast Asia during boreal summer. The latter seems to correspond to the weakening, southeastward shift of the Asian summer monsoon system resulting from reduced heat contrast between the Eurasian continent and the Pacific and Indian Oceans when a cooling over the Tibetan Plateau was imposed. The simulation results suggest that the snow and glacier environment over the Tibetan Plateau is an important factor for mid-Holocene climate change in the areas highly influenced by the Asian monsoon.

  7. Quality audit--a review of the literature concerning delivery of continence care.

    PubMed

    Swaffield, J

    1995-09-01

    This paper outlines the role of quality audit within the framework of quality assurance, presenting the concurrent and retrospective approaches available. The literature survey provides a review of the limited audit tools available and their application to continence services and care delivery, as well as attempts to produce tools from national and local standard setting. Audit is part of a process; it can involve staff, patients and their relatives and the team of professionals providing care, as well as focusing on organizational and management levels. In an era of market delivery of services there is a need to justify why audit is important to continence advisors and managers. Effectiveness, efficiency and economics may drive the National Health Service, but quality assurance, which includes standards and audit tools, offers the means to ensure the quality of continence services and care to patients and auditing is also required in the purchaser/provider contracts for patient services. An overview and progress to date of published and other a projects in auditing continence care and service is presented. By outlining and highlighting the audit of continence service delivery and care as a basis on which to build quality assurance programmes, it is hoped that this knowledge will be shared through the setting up of a central auditing clearing project.

  8. Smart wireless continence management system for persons with dementia.

    PubMed

    Wai, Aung Aung Phyo; Fook, Victor Foo Siang; Jayachandran, Maniyeri; Biswas, Jit; Nugent, Chris; Mulvenna, Maurice; Lee, Jer-En; Kiat, Philp Yap Lian

    2008-10-01

    Incontinence is highly prevalent in the elderly population, especially in nursing home residents with dementia. It is a distressing and costly health problem that affects not only the patients but also the caregivers. Effective continence management is required to provide quality care, and to eliminate high labor costs and annoyances to the caregivers resulting from episodes of incontinence. This paper presents the design, development, and preliminary deployment of a smart wireless continence management system for dementia-impaired elderly or patients in institutional care settings such as nursing homes and hospitals. Specifically, the mote wireless platform was used to support the deployment of potentially large quantities of wetness sensors with wider coverage and with dramatically less complexity and cost. It consists of an intelligent signal relay mechanism so that the residents are free to move about in the nursing home or hospital and allows personalized continence management service. Preliminary results from a trial in a local nursing home are promising and can significantly improve the quality of care for patients.

  9. Database for landscape-scale carbon monitoring sites

    Treesearch

    Jason A. Cole; Kristopher D. Johnson; Richard A. Birdsey; Yude Pan; Craig A. Wayson; Kevin McCullough; Coeli M. Hoover; David Y. Hollinger; John B. Bradford; Michael G. Ryan; Randall K. Kolka; Peter Wieshampel; Kenneth L. Clark; Nicholas S. Skowronski; John Hom; Scott V. Ollinger; Steven G. McNulty; Michael J. Gavazzi

    2013-01-01

    This report describes the database used to compile, store, and manage intensive ground-based biometric data collected at research sites in Colorado, Minnesota, New Hampshire, New Jersey, North Carolina, and Wyoming, supporting research activities of the U.S. North American Carbon Program (NACP). This report also provides details of each site, the sampling design and...

  10. Impact of metabolic syndrome on early recovery of continence after robot-assisted radical prostatectomy.

    PubMed

    Nishikawa, Masatomo; Watanabe, Hiromitsu; Kurahashi, Toshifumi

    2017-09-01

    To evaluate the impact of metabolic syndrome on the early recovery of urinary continence after robot-assisted radical prostatectomy. The present study included a total of 302 consecutive Japanese patients with clinically localized prostate cancer who underwent robot-assisted radical prostatectomy. In this study, postoperative urinary continence was defined as no leak or the use of a security pad. The continence status was assessed by interviews before and 1 and 3 months after robot-assisted radical prostatectomy. Metabolic syndrome was defined as follows: body mass index ≥25 kg/m 2 and two or more of the following: hypertension, diabetes mellitus and dyslipidemia. The effect of the presence of metabolic syndrome on the continence status of these patients was retrospectively examined. A total of 116 (38.4%) and 203 (67.2%) of the 302 patients were continent at 1 and 3 months after robot-assisted radical prostatectomy, respectively. A total of 31 (10.3%) patients were judged to have metabolic syndrome. Despite the operative time being longer in patients with metabolic syndrome, no significant differences were observed in the remaining preoperative, intraoperative or postoperative variables between patients with or without metabolic syndrome. On multivariate logistic regression analysis, metabolic syndrome and the duration of hospitalization were significantly correlated with the 1-month continence status. Similarly, metabolic syndrome and estimated blood loss during surgery were independent predictors of continence rates at 3 months after robot-assisted radical prostatectomy. These findings suggest that the presence of metabolic syndrome could have a significant impact on the early recovery of urinary continence after robot-assisted radical prostatectomy. © 2017 The Japanese Urological Association.

  11. Novel rechargeable calcium phosphate nanocomposite with antibacterial activity to suppress biofilm acids and dental caries.

    PubMed

    Al-Dulaijan, Yousif A; Cheng, Lei; Weir, Michael D; Melo, Mary Anne S; Liu, Huaibing; Oates, Thomas W; Wang, Lin; Xu, Hockin H K

    2018-05-01

    Rechargeable calcium phosphate (CaP) composites were developed recently. However, none of the rechargeable CaP composites was antibacterial. The objectives of this study were to develop the first rechargeable CaP composite that was antibacterial, and to investigate the effects of adding dimethylaminohexadecyl methacrylate (DMAHDM) into rechargeable CaP composite on ion rechargeability and re-release as well as biofilm properties. DMAHDM was synthesized via a Menschutkin reaction. Nanoparticles of amorphous calcium phosphate (NACP) were synthesized using a spray-drying technique. The resin contained ethoxylated bisphenol A dimethacrylate (EBPADMA) and pyromellitic glycerol dimethacrylate (PMGDM). Two composites were fabricated: rechargeable NACP composite, and rechargeable NACP-DMAHDM composite. Mechanical properties and ion release and recharge were measured. A dental plaque microcosm biofilm model using saliva was tested. Flexural strength and elastic modulus of rechargeable NACP and NACP-DMAHDM composites matched commercial control composite (p > 0.1). NACP-DMAHDM inhibited biofilm metabolic activity and lactic acid, and reduced biofilm colony-forming units (CFU) by 3-4 log. NACP and NACP-DMAHDM showed similar Ca and P ion recharge and re-release (p > 0.1). Therefore, adding DMAHDM did not compromise the ion rechargeability. One recharge yielded continuous release for 42 d. The release was maintained at the same level with increasing number of recharge cycles, indicating long-term ion release and remineralization capability. The first CaP rechargeable and antibacterial composite was developed. Adding DMAHDM into the rechargeable NACP composite did not adversely affect the Ca and P ion release and recharge, and the composite had much less biofilm growth and lactic acid production, with CFU reduction by 3-4 log. This novel CaP rechargeable composite with long-term remineralization and antibacterial properties is promising for tooth restorations to inhibit

  12. OxyContin in Ontario: the multiple materialities of prescription painkillers.

    PubMed

    King, Samantha

    2014-05-01

    In the past decade, OxyContin diversion and misusehave been firmly established in Ontarian public discourse as serious problems requiring major intervention.This article contextualizes and theorizesthe processes through which the marketing of the prescription opioid and its subsequent problematization occurred. Theanalysis refuses the impossible choice between the 'deserving pain patient' and the 'undeserving addict,' between the war on pain and the war on drugs, and between a notion of OxyContin as either miracle panacea or destructive poison. Rather than falling in step with these binaries, OxyContinis theorized across them, or multiply, with the aim of moving beyond established moral and theoretical registers for exploring embodied consumption. This discursive study is based on a broad range of texts collected between 2009-2013: Hansard reports from the Legislative Assembly of Ontario; newspaper, magazine, and internet coverage of OxyContin; and policy documents, research reports, and position papers and news releases produced by government agencies, advocacy organizations, professional bodies, think tanks, tribal councils, and law enforcement agencies. Pharmaceutical industry and state actors have attempted to dualistically parse disparate materializations of OxyContin, a tactic that intensified as media pressure helped produce the notion of a public health crisis and, implicitly, a crisis of welfare dependence. By focusing on the (impossible) task of stratifying proper from improper use, the drug's advocatessought to secure the integrity of opioid painkillers and to protect their materialization as vehicles for maintaining a body that is normal, stable, and in control, as opposed to a body of excess that threatens to expose the consumerist logic of contemporary medicine. Attempts to contain the multiplicity of OxyContin result in the further entrenchment of privatized and individualized approaches to pain and painkilling and serve to undermine rather than

  13. Magnetotelluric Investigations of Convergent Margins and of Incipient Rifting: Preliminary Results from the EarthScope MT Transportable Array and MT FlexArray Deployments in Cascadia and in the North American Mid-Continent Region

    NASA Astrophysics Data System (ADS)

    Schultz, A.; Bedrosian, P.; Key, K.; Livelybrooks, D.; Egbert, G. D.; Bowles-martinez, E.; Wannamaker, P. E.

    2014-12-01

    We report on preliminary analyses of data from the EarthScope MT Transportable Array, and from two high-resolution EarthScope MT studies in Cascadia. The first of these, iMUSH, is acquiring wideband MT data at 150 sites, as well as active and passive seismic data in SW Washington (including Mounts Saint Helens, Adams and Rainier). iMUSH seeks to determine details of crustal magma transport and storage, and to resolve major tectonic controls on volcanism along the arc. iMUSH may help to settle a debate over the origin of the SW Washington Crustal Conductor (SWCC), which covers ~5000 km2and that has alternately been attributed to accreted Eocene metasediments or to an extensive region of partial melt in the lower crust beneath the three volcanoes. The iMUSH array is continguous with an amphibious ~150 station MT experiment (MOCHA) onshore and offshore of the Washington and Oregon forearc. MOCHA iwill image the crust and upper mantle of the subduction system in 3D, constraining the fluid input to the system from offshore and the distribution of fluids released from the down-going slab, including along the transitional zone where Episodic Tremor and Slip occurs. Our goal is to refine our understanding of the segmentation, structure and fluid distribution along the convergent margin segments, and their relationship to the spatial pattern of ETS. In contrast to the active Cascadia margin, the Mid-Continent Rift (MCR) is the trace of a massive igneous event that nearly split North America 1.1 billion years ago. Initial results from 3D inversion of MT Transportable Array data show less fine-scale heterogeneity in the upper mantle (250 km depth) than is evident in western, tectonic North America, but a division at the base of thick lithosphere, with higher conductivities beneath and immediately south of the Great Lakes, than to the south. From the base of the lithosphere to the Moho, this high conductivity feature narrows, ultimately disappearing in the mid-crust. In the

  14. National audit of continence care for older people: management of urinary incontinence.

    PubMed

    Wagg, Adrian; Potter, Jonathan; Peel, Penny; Irwin, Penny; Lowe, Derek; Pearson, Michael

    2008-01-01

    the Department of Health report 'Good practice in continence services' highlights the need for proper assessment and management of urinary incontinence. The National Service Framework for Older People required service providers to establish integrated continence services by April 2004. A national audit was conducted to assess the quality of continence care for older people and whether these requirements have been met. the audit studied incontinent individuals of 65 years and over. Each site returned data on organisational structure and the process of 20 patients' care. Data were submitted via the internet, and all were anonymous. the national audit was conducted across England, Wales and Northern Ireland. Data on the care of patients/residents with bladder problems were returned by 141/326 (43%) of primary care trusts (PCT), by 159/196 (81%) of secondary care trusts (involving 198 hospitals) and by 29/309 (9%) of invited care homes. In all 58% of PCT, 48% of hospitals and 74% of care homes reported that integrated continence services existed in their area. Whilst basic provision of care appeared to be in place, the audit identified deficiencies in the organisation of services, and in the assessment and management of urinary incontinence in the elderly. the results of this audit indicate that the requirement for integrated continence services has not yet been met. Assessment and care by professionals directly looking after the older person were often lacking. There is an urgent need to re-establish the fundamentals of continence care into the practice of medical and nursing staff and action needs to be taken with regard to the establishment of truly integrated, quality services in this neglected area of practice.

  15. Continents on the Move or "Where in the World Did Antarctica Come From?"

    ERIC Educational Resources Information Center

    CSTA Journal, 1995

    1995-01-01

    Presents an activity in which students trace the movement of the continents over the past 600 million years to help them understand how the continents' size and position have changed over time. Includes map puzzle pieces. (MKR)

  16. Improving and ensuring best practice continence management in residential aged care.

    PubMed

    Heckenberg, Gayle

    2008-06-01

    Background  Continence Management within residential aged care is an every day component of care that requires assessment, implementation of strategies, resource allocation and evaluation. At times the management of incontinence of aged residents can be challenging and unsuccessful. The project chosen through the Clinical Fellowship program was Continence Management with the aim of raising awareness of best practice to assist in improving and providing person-centred resident care. Aims/objectives •  Review the literature on best practice management of incontinence •  Evaluate current practice in continence management for elderly residents within residential aged care services •  Improve adherence to best practice strategies of care for incontinence •  Raise awareness within the nursing home of the best practice management of incontinence •  Promote appropriate and effective use of resources for continence management •  Deliver individualised person-centred care to residents. •  Ensure best practice in continence management Methods  The Joanna Briggs Institute (JBI) Practical Application of Clinical Evidence System clinical audit tool was utilised to measure current practice against best practice. The results identify gaps that require improvement. The Getting Research into Practice process then allowed analysis of the level of compliance with each of the audit criteria, which would identify any barriers in implementing a selected course of action and aim to improve compliance. The project team was consulted with additional stakeholder consultation to form an action plan and implement strategies to improve practice. Results  Although 100% compliance with all audit criteria in audit 1 and 2 was not achieved, there was improvement in the criteria concerning the documented fluid intake for residents. Further strategies have been identified and implemented and this continues to be a 'work in progress'. Staff now have an acute awareness

  17. Versatile silicon-waveguide supercontinuum for coherent mid-infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Nader, Nima; Maser, Daniel L.; Cruz, Flavio C.; Kowligy, Abijith; Timmers, Henry; Chiles, Jeff; Fredrick, Connor; Westly, Daron A.; Nam, Sae Woo; Mirin, Richard P.; Shainline, Jeffrey M.; Diddams, Scott

    2018-03-01

    Laser frequency combs, with their unique combination of precisely defined spectral lines and broad bandwidth, are a powerful tool for basic and applied spectroscopy. Here, we report offset-free, mid-infrared frequency combs and dual-comb spectroscopy through supercontinuum generation in silicon-on-sapphire waveguides. We leverage robust fabrication and geometrical dispersion engineering of nanophotonic waveguides for multi-band, coherent frequency combs spanning 70 THz in the mid-infrared (2.5 μm-6.2 μm). Precise waveguide fabrication provides significant spectral broadening with engineered spectra targeted at specific mid-infrared bands. We characterize the relative-intensity-noise of different bands and show that the measured levels do not pose any limitation for spectroscopy applications. Additionally, we use the fabricated photonic devices to demonstrate dual-comb spectroscopy of a carbonyl sulfide gas sample at 5 μm. This work forms the technological basis for applications such as point sensors for fundamental spectroscopy, atmospheric chemistry, trace and hazardous gas detection, and biological microscopy.

  18. Improving continence services for older people from the service-providers’ perspective: a qualitative interview study

    PubMed Central

    Orrell, Alison; McKee, Kevin; Dahlberg, Lena; Gilhooly, Mary; Parker, Stuart

    2013-01-01

    Objective To examine in depth the views and experiences of continence service leads in England on key service and continence management characteristics in order to identify and to improve our understanding of barriers to a good-quality service and potential facilitators to develop and to improve services for older people with urinary incontinence (UI). Design Qualitative semistructured interviews using a purposive sample recruited across 16 continence services. Setting 3 acute and 13 primary care National Health Service Trusts in England. Participants 16 continence service leads in England actively treating and managing older people with UI. Results In terms of barriers to a good-quality service, participants highlighted a failure on the part of commissioners, managers and other health professionals in recognising the problem of UI and in acknowledging the importance of continence for older people and prevalent negative attitudes towards continence and older people. Patient assessment and continence promotion regardless of age, rather than pad provision, were identified as important steps for a good-quality service for older people with UI. More rapid and appropriate patient referral pathways, investment in service capacity, for example, more trained staff and strengthened interservice collaborations and a higher profile within medical and nurse training were specified as being important facilitators for delivering an equitable and high-quality continence service. There is a need, however, to consider the accounts given by our participants as perhaps serving the interests of their professional group within the context of interprofessional work. Conclusions Our data point to important barriers and facilitators of a good-quality service for older people with UI, from the perspective of continence service leads. Further research should address the views of other stakeholders, and explore options for the empirical evaluation of the effectiveness of identified service

  19. Evaluation of urinary extravasation and results after continence-preserving radical retropubic prostatectomy.

    PubMed

    Varkarakis, John; Wirtenberger, Walter; Pinggera, Germar-Michael; Berger, Andreas; Harabayashi, Toru; Bartsch, Georg; Horninger, Wolfgang

    2004-11-01

    To evaluate the feasibility of urinary catheter removal 10 days after a radical retropubic prostatectomy (RRP) by assessing the incidence of urinary extravasation and its effect on postoperative stricture and continence rates. During a 4.5-year period, 619 patients undergoing RRP were evaluated. If no extravasation was detected on gravity cystography, the urinary catheter was removed 10 days after RRP. In patients with significant extravasation the catheter was left in place for 3 weeks. Overall stricture and continence rates were recorded in patients at 3, 6 and 12 months after surgery. There was extravasation during cystography in 29 patients (4.6%). At 3, 6 and 12 months, continence rates after catheter removal at 10 days were 74.9%, 87.9%, and 93.6%, respectively, while in the late-removal group they were 72.4%, 84.6% and 90.9%, respectively, with no significant difference between the groups. At 3 months the overall continence rate was 74.8% and at 12 months up to 93.5%. There was no difference in stricture rates between the groups, with an overall stricture rate of 0.7%. Catheter removal 10 days after RRP is feasible, giving excellent early and late continence rates, with low anastomotic stricture rates obtained using good surgical technique. Extravasation at 10 days was rare and with proper management did not influence the final results.

  20. Remineralization of demineralized enamel via calcium phosphate nanocomposite.

    PubMed

    Weir, M D; Chow, L C; Xu, H H K

    2012-10-01

    Secondary caries remains the main problem limiting the longevity of composite restorations. The objective of this study was to investigate the remineralization of demineralized human enamel in vitro via a nanocomposite containing nanoparticles of amorphous calcium phosphate (NACP). NACP were synthesized by a spray-drying technique and incorporated into a dental resin. First, caries-like subsurface enamel lesions were created via an acidic solution. Then, NACP nanocomposite or a commercial fluoride-releasing control composite was placed on the demineralized enamel, along with control enamel without a composite. These specimens were then treated with a cyclic demineralization/remineralization regimen for 30 days. Quantitative microradiography showed typical enamel subsurface demineralization before cyclic demineralization/remineralization treatment, and significant remineralization in enamel under the NACP nanocomposite after the demineralization/remineralization treatment. The NACP nanocomposite had the highest enamel remineralization (mean ± SD; n = 6) of 21.8 ± 3.7%, significantly higher than the 5.7 ± 6.9% for fluoride-releasing composite (p < 0.05). The enamel group without composite had further demineralization of -26.1 ± 16.2%. In conclusion, a novel NACP nanocomposite was effective in remineralizing enamel lesions in vitro. Its enamel remineralization was 4-fold that of a fluoride-releasing composite control. Combined with the good mechanical and acid-neutralization properties reported earlier, the new NACP nanocomposite is promising for remineralization of demineralized tooth structures.

  1. Remineralization of Demineralized Enamel via Calcium Phosphate Nanocomposite

    PubMed Central

    Weir, M.D.; Chow, L.C.; Xu, H.H.K.

    2012-01-01

    Secondary caries remains the main problem limiting the longevity of composite restorations. The objective of this study was to investigate the remineralization of demineralized human enamel in vitro via a nanocomposite containing nanoparticles of amorphous calcium phosphate (NACP). NACP were synthesized by a spray-drying technique and incorporated into a dental resin. First, caries-like subsurface enamel lesions were created via an acidic solution. Then, NACP nanocomposite or a commercial fluoride-releasing control composite was placed on the demineralized enamel, along with control enamel without a composite. These specimens were then treated with a cyclic demineralization/remineralization regimen for 30 days. Quantitative microradiography showed typical enamel subsurface demineralization before cyclic demineralization/remineralization treatment, and significant remineralization in enamel under the NACP nanocomposite after the demineralization/remineralization treatment. The NACP nanocomposite had the highest enamel remineralization (mean ± SD; n = 6) of 21.8 ± 3.7%, significantly higher than the 5.7 ± 6.9% for fluoride-releasing composite (p < 0.05). The enamel group without composite had further demineralization of −26.1 ± 16.2%. In conclusion, a novel NACP nanocomposite was effective in remineralizing enamel lesions in vitro. Its enamel remineralization was 4-fold that of a fluoride-releasing composite control. Combined with the good mechanical and acid-neutralization properties reported earlier, the new NACP nanocomposite is promising for remineralization of demineralized tooth structures. PMID:22933607

  2. Evidence from Ocean Drilling Program Leg 149 mafic igneous rocks for oceanic crust in the Iberia Abyssal Plain ocean-continent transition zone

    NASA Astrophysics Data System (ADS)

    Seifert, Karl E.; Chang, Cheng-Wen; Brunotte, Dale A.

    1997-04-01

    Leg 149 of the Ocean Drilling Program explored the ocean-continent transition (OCT) on the Iberia Abyssal Plain and its role in the opening of the Atlantic Ocean approximately 130 Ma. Mafic igneous rocks recovered from Holes 899B and 900A have Mid-Ocean Ridge Basalt (MORB) trace element and isotopic characteristics indicating that a spreading center was active during the opening of the Iberia Abyssal Plain OCT. The Hole 899B weathered basalt and diabase clasts have transitional to enriched MORB rare earth element characteristics, and the Hole 900A metamorphosed gabbros have MORB initial epsilon Nd values between +6 and +11. During the opening event the Iberia Abyssal Plain OCT is envisioned to have resembled the central and northern parts of the present Red Sea with localized spreading centers and magma chambers producing localized patches of MORB mafic rocks. The lack of a normal ocean floor magnetic anomaly pattern in the Iberia Abyssal Plain means that a continuous spreading center similar to that observed in the present southern Red Sea was not formed before spreading ceased in the Iberia Abyssal Plain OCT and jumped to the present Mid-Atlantic Ridge.

  3. Paleogeographic changes across the Pennsylvanian-Permian boundary within the Mid-Continent (USA) inferred from detrital zircon geochronology of continental deposits

    NASA Astrophysics Data System (ADS)

    Soreghan, M. J.; Soreghan, G. S.

    2017-12-01

    The Permo-Pennsylvanian was characterized by intense orogenesis associated with Pangaean assembly, and profound climate shifts as earth transitioned from full icehouse conditions in the Pennsylvanian-early Permian to collapse into greenhouse conditions by latest Permian time. The modern U.S. Midcontinent was part of equatorial western Pangaea (North America) sandwiched between a continental-scale orogenic zone to the east and south (Appalachian-Ouachita-Marathon orogenic belt) and a series of basement-cored, intra-plate uplifts along western Pangaea (Ancestral Rocky Mountains). Here, we present a compilation of detrital zircon geochronology data from the Permo-Pennsylvanian of the Midcontinent as well as coeval strata of the east and west to explore sediment dispersal and potential tectonic and climatic influences on these provenance signatures. Zircon provenance data come from mostly eolian and fluvial silt- and sandstones of Early Pennsylvanian through Mid Permian age, although some data include marine sandstones. Our new data were acquired by LA-ICPMS at the University of Arizona Laserchron, and predominant age groups include >2500 Ma (Archean), 1600-1800 Ma (Yavapai-Matzatzal), 1300-900 Ma (Grenville), 790-570 Ma (Neoproterozoic), and 480-360 (E-M Paleozoic). However, the relative distributions of these populations exhibit distinctive temporal differences, especially across the Pennsylvanian-Permian boundary, but also spatially in comparison to published data from the Appalachian-Ouachita-Marathon basin, Ancestral Rocky Mountain basins, and the western Pangaean margin. Although the Central Pangaean Mountains, and in particular the Grenville-age basement rocks, were a dominant source of sediment to the Midcontinent, the data suggest an abrupt introduction of Neoproterozoic zircons in the early Permian. This signature also appears within the Ancestral Rocky Mountains region, but is rare along the western margin and the Appalachian basin in the early Permian. This

  4. Anorectal function investigations in incontinent and continent patients. Differences and discriminatory value.

    PubMed

    Felt-Bersma, R J; Klinkenberg-Knol, E C; Meuwissen, S G

    1990-06-01

    Anal manometry, rectal capacity measurement, and the saline-infusion test were performed in 350 patients, 178 of whom had fecal incontinence and 172 of whom were continent. Anal manometry was also performed in 80 control subjects, whose results were compared with the patients. Women and older patients exhibited lower pressures. Compared with continent patients, incontinent patients had lower anal sphincter pressures at rest and during squeeze, a smaller rectal capacity, and leaked earlier and more with the saline infusion test. Differentiation between incontinent and continent patients was not possible with a single test because there was complete overlap. The maximum squeeze pressure showed the best discrimination. Combining the three tests did not show better discrimination than any individual test. Anal pressure and rectal capacity below the normal range only were found in very few incontinent patients. The authors' study demonstrates that no prediction can be made about continence with anorectal function tests. Therefore, in the individual patient, an abnormal result in one test must be interpreted with caution and only in relationship with other tests, especially when therapeutic surgery is considered.

  5. A simplified technique for continent urinary diversion: an all-stapled colonic reservoir.

    PubMed

    Parra, R O

    1991-12-01

    A simple continent colonic reservoir was constructed in its entirety with the aid of surgical stapling techniques in 17 men and 10 women. In 5 men an orthotopic pouch was created and in the rest a continent stoma was designed. Detubularization of the entire colonic segment assures a low pressure system with disruption of directional peristaltic activity. The ureters are implanted by simply burying them in a mucosal furrow. Operative time required for the creation of the reservoir (excluding time for cystectomy) has ranged between 70 and 140 minutes (mean 95.4 minutes). With a followup of 9 to 60 months (mean 22.8 months) continence has been achieved in all but 1 patient with no ureteral reflux or obstruction. Urodynamically the pouch has achieved a large capacity (mean 750 cc) with low filling pressures (8.1 cm. water) because of technical ease of construction together with a shortened operative time due to the stapling techniques. This form of bladder replacement offers an option for select patients in whom continent urinary diversion is contemplated.

  6. Effect of calcium phosphate nanocomposite on in vitro remineralization of human dentin lesions.

    PubMed

    Weir, Michael D; Ruan, Jianping; Zhang, Ning; Chow, Laurence C; Zhang, Ke; Chang, Xiaofeng; Bai, Yuxing; Xu, Hockin H K

    2017-09-01

    Secondary caries is a primary reason for dental restoration failures. The objective of this study was to investigate the remineralization of human dentin lesions in vitro via restorations using nanocomposites containing nanoparticles of amorphous calcium phosphate (NACP) or NACP and tetracalcium phosphate (TTCP) for the first time. NACP was synthesized by a spray-drying technique and incorporated into a resin consisting of ethoxylated bisphenol A dimethacrylate (EBPADMA) and pyromellitic glycerol dimethacrylate (PMGDM). After restoring the dentin lesions with nanocomposites as well as a non-releasing commercial composite control, the specimens were treated with cyclic demineralization (pH 4, 1h per day) and remineralization (pH 7, 23h per day) for 4 or 8 weeks. Calcium (Ca) and phosphate (P) ion releases from composites were measured. Dentin lesion remineralization was measured at 4 and 8 weeks by transverse microradiography (TMR). Lowering the pH increased ion release of NACP and NACP-TTCP composites. At 56 days, the released Ca concentration in mmol/L (mean±SD; n=3) was (13.39±0.72) at pH 4, much higher than (1.19±0.06) at pH 7 (p<0.05). At 56 days, P ion concentration was (5.59±0.28) at pH 4, much higher than (0.26±0.01) at pH 7 (p<0.05). Quantitative microradiography showed typical subsurface dentin lesions prior to the cyclic demineralization/remineralization treatment, and dentin remineralization via NACP and NACP-TTCP composites after 4 and 8 weeks of treatment. At 8 weeks, NACP nanocomposite achieved dentin lesion remineralization (mean±SD; n=15) of (48.2±11.0)%, much higher than (5.0±7.2)% for dentin in commercial composite group after the same cyclic demineralization/remineralization regimen (p<0.05). Novel NACP-based nanocomposites were demonstrated to achieve dentin lesion remineralization for the first time. These results, coupled with acid-neutralization and good mechanical properties shown previously, indicate that the NACP

  7. Effect of amorphous calcium phosphate and silver nanocomposites on dental plaque microcosm biofilms

    PubMed Central

    Cheng, Lei; Weir, Michael D.; Xu, Hockin H. K.; Antonucci, Joseph M.; Lin, Nancy J.; Lin-Gibson, Sheng; Xu, Sarah M.; Zhou, Xuedong

    2012-01-01

    A dental composite containing amorphous calcium phosphate nanoparticles (NACP) was developed that released calcium (Ca) and phosphate (PO4) ions and possessed acid-neutralization capability. There has been little study on incorporation of antibacterial agents into calcium phosphate composites. The objective of this study was to investigate the effect of silver nanoparticle (NAg) mass fraction in NACP nanocomposite on mechanical properties and dental plaque microcosm biofilm for the first time. NACP nanoparticles of 116 nm were synthesized via a spray-drying technique. NAg nanoparticles were synthesized using Ag 2-ethylhexanoate and 2-(tert-butylamino)ethyl methacrylate, yielding NAg of particle size of 2.7 nm that were well-dispersed in the resin. Five NACP nanocomposites were fabricated with NAg mass fractions of 0, 0.028, 0.042, 0.088, and 0.175%, respectively. Mechanical properties of NACP nanocomposites containing 0–0.042% of NAg matched those of a commercial composite without antibacterial activity. Live/dead assay of dental plaque microcosm biofilms showed complete coverage with live bacteria on commercial composite. However, there were increasingly more dead bacteria with higher NAg content in the NACP nanocomposite. Colony-forming unit (CFU) counts for total microorganisms, total Streptococci, and mutans Streptococci for NACP nanocomposite with 0.042% NAg were about 1/4 those of commercial composite. Lactic acid production on NACP nanocomposite with 0.042% NAg was 1/3 that on commercial composite. In conclusion, novel NACP–NAg nanocomposites were developed which possessed good mechanical properties and potent antibacterial properties, with substantially reduced biofilm viability and lactic acid production. Hence, the NACP–NAg nanocomposites are promising for dental restorations with remineralizing and antibacterial capabilities. PMID:22566464

  8. Historical deforestation locally increased the intensity of hot days in northern mid-latitudes

    NASA Astrophysics Data System (ADS)

    Lejeune, Quentin; Davin, Edouard L.; Gudmundsson, Lukas; Winckler, Johannes; Seneviratne, Sonia I.

    2018-05-01

    The effects of past land-cover changes on climate are disputed1-3. Previous modelling studies have generally concluded that the biogeophysical effects of historical deforestation led to an annual mean cooling in the northern mid-latitudes3,4, in line with the albedo-induced negative radiative forcing from land-cover changes since pre-industrial time reported in the most recent Intergovernmental Panel on Climate Change report5. However, further observational and modelling studies have highlighted strong seasonal and diurnal contrasts in the temperature response to deforestation6-10. Here, we show that historical deforestation has led to a substantial local warming of hot days over the northern mid-latitudes—a finding that contrasts with most previous model results11,12. Based on observation-constrained state-of-the-art climate-model experiments, we estimate that moderate reductions in tree cover in these regions have contributed at least one-third of the local present-day warming of the hottest day of the year since pre-industrial time, and were responsible for most of this warming before 1980. These results emphasize that land-cover changes need to be considered when studying past and future changes in heat extremes, and highlight a potentially overlooked co-benefit of forest-based carbon mitigation through local biogeophysical mechanisms.

  9. Monitoring of Internet Forums to Evaluate Reactions to the Introduction of Reformulated OxyContin to Deter Abuse

    PubMed Central

    Coplan, Paul M; Black, Ryan A; Weber, Sarah E; Chilcoat, Howard D; Butler, Stephen F

    2014-01-01

    Background Reformulating opioid analgesics to deter abuse is one approach toward improving their benefit-risk balance. To assess sentiment and attempts to defeat these products among difficult-to-reach populations of prescription drug abusers, evaluation of posts on Internet forums regarding reformulated products may be useful. A reformulated version of OxyContin (extended-release oxycodone) with physicochemical properties to deter abuse presented an opportunity to evaluate posts about the reformulation in online discussions. Objective The objective of this study was to use messages on Internet forums to evaluate reactions to the introduction of reformulated OxyContin and to identify methods aimed to defeat the abuse-deterrent properties of the product. Methods Posts collected from 7 forums between January 1, 2008 and September 30, 2013 were evaluated before and after the introduction of reformulated OxyContin on August 9, 2010. A quantitative evaluation of discussion levels across the study period and a qualitative coding of post content for OxyContin and 2 comparators for the 26 month period before and after OxyContin reformulation were conducted. Product endorsement was estimated for each product before and after reformulation as the ratio of endorsing-to-discouraging posts (ERo). Post-to-preintroduction period changes in ERos (ie, ratio of ERos) for each product were also calculated. Additionally, post content related to recipes for defeating reformulated OxyContin were evaluated from August 9, 2010 through September 2013. Results Over the study period, 45,936 posts related to OxyContin, 18,685 to Vicodin (hydrocodone), and 23,863 to Dilaudid (hydromorphone) were identified. The proportion of OxyContin-related posts fluctuated between 6.35 and 8.25 posts per 1000 posts before the reformulation, increased to 10.76 in Q3 2010 when reformulated OxyContin was introduced, and decreased from 9.14 in Q4 2010 to 3.46 in Q3 2013 in the period following the reformulation

  10. Monitoring of internet forums to evaluate reactions to the introduction of reformulated OxyContin to deter abuse.

    PubMed

    McNaughton, Emily C; Coplan, Paul M; Black, Ryan A; Weber, Sarah E; Chilcoat, Howard D; Butler, Stephen F

    2014-05-02

    Reformulating opioid analgesics to deter abuse is one approach toward improving their benefit-risk balance. To assess sentiment and attempts to defeat these products among difficult-to-reach populations of prescription drug abusers, evaluation of posts on Internet forums regarding reformulated products may be useful. A reformulated version of OxyContin (extended-release oxycodone) with physicochemical properties to deter abuse presented an opportunity to evaluate posts about the reformulation in online discussions. The objective of this study was to use messages on Internet forums to evaluate reactions to the introduction of reformulated OxyContin and to identify methods aimed to defeat the abuse-deterrent properties of the product. Posts collected from 7 forums between January 1, 2008 and September 30, 2013 were evaluated before and after the introduction of reformulated OxyContin on August 9, 2010. A quantitative evaluation of discussion levels across the study period and a qualitative coding of post content for OxyContin and 2 comparators for the 26 month period before and after OxyContin reformulation were conducted. Product endorsement was estimated for each product before and after reformulation as the ratio of endorsing-to-discouraging posts (ERo). Post-to-preintroduction period changes in ERos (ie, ratio of ERos) for each product were also calculated. Additionally, post content related to recipes for defeating reformulated OxyContin were evaluated from August 9, 2010 through September 2013. Over the study period, 45,936 posts related to OxyContin, 18,685 to Vicodin (hydrocodone), and 23,863 to Dilaudid (hydromorphone) were identified. The proportion of OxyContin-related posts fluctuated between 6.35 and 8.25 posts per 1000 posts before the reformulation, increased to 10.76 in Q3 2010 when reformulated OxyContin was introduced, and decreased from 9.14 in Q4 2010 to 3.46 in Q3 2013 in the period following the reformulation. The sentiment profile for OxyContin

  11. Serum levels of 25-hydroxyvitamin D in a year of residence on the Antarctic continent.

    PubMed

    Oliveri, M B; Mautalen, C; Bustamante, L; Gómez García, V

    1994-06-01

    Since exposure to sunlight is the main source of vitamin D in human beings and skin photosynthesis decreases markedly as the latitude increases, we studied the changes in serum 25-hydroxyvitamin D (25(OH)D) levels in young healthy men who lived in the Antarctic Continent during 1 year. Blood was drawn in the fasting state every 2 months from March 1990 to January 1991 to determine the serum levels of calcium, alkaline phosphatase and 25(OH)D. 19 healthy volunteers, who left Buenos Aires (34 degrees S) during the 1990 summer, arriving at the Antarctic bases at the end of January (Belgrano) and in mid-March (San Martín) and stayed there up to summer 1991. Serum calcium did not change significantly throughout the year. Serum alkaline phosphatase levels were not different comparing the beginning to the end of the year, but autumn and winter levels were lower (P < 0.05). At Belgrano Base the serum 25(OH)D levels (ng/ml) decreased from (mean +/- SD) 18.7 +/- 7.4 (March) to 10.0 +/- 4.3 (July) (P < 0.005) and did not recover for the rest of the year. At San Martín Base the serum 25(OH)D levels descended from 22.0 +/- 5.4 in March to 12.2 +/- 3.7 in August (P < 0.02) and did not increase even at the beginning of summer (January) except in two men with frequent outdoor activities. The levels of 25(OH)D of healthy men living in the Antarctic continent decreased to approximately 46% of the initial values and did not increase even at the onset of summer. Further studies should determine the effect of these changes upon calcium-regulating hormones and bone metabolism.

  12. How Do People Make Continence Care Happen? An Analysis of Organizational Culture in Two Nursing Homes

    ERIC Educational Resources Information Center

    Lyons, Stacie Salsbury

    2010-01-01

    Purpose: Although nursing homes (NHs) are criticized for offering poor quality continence care, little is known about the organizational processes that underlie this care. This study investigated the influence of organizational culture on continence care practices in two NHs. Design and Methods: This ethnographic study explored continence care…

  13. Coupling mid-infrared light from a photonic crystal waveguide to metallic transmission lines

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blanco-Redondo, Andrea, E-mail: andrea.blanco@tecnalia.com, E-mail: r.hillenbrand@nanogune.eu; Dpto. Electronica y Telecom., E.T.S. Ingeniería Bilbao, UPV/EHU, Alda. Urquijo, 48103 Bilbao, Bizkaia; Sarriugarte, Paulo

    2014-01-06

    We propose and theoretically study a hybrid structure consisting of a photonic crystal waveguide (PhC-wg) and a two-wire metallic transmission line (TL), engineered for efficient transfer of mid-infrared (mid-IR) light between them. An efficiency of 32% is obtained for the coupling from the transverse magnetic (TM) photonic mode to the symmetric mode of the TL, with a predicted intensity enhancement factor of 53 at the transmission line surface. The strong coupling is explained by the small phase velocity mismatch and sufficient spatial overlapping between the modes. This hybrid structure could find applications in highly integrated mid-IR photonic-plasmonic devices for biologicalmore » and gas sensing, among others.« less

  14. Sun Unleashes Mid-level Flare

    NASA Image and Video Library

    2015-06-22

    The sun emitted a mid-level solar flare, peaking at 2:23 EDT on June 22, 2015. NASA’s Solar Dynamics Observatory, which watches the sun constantly, captured an image of the event. Solar flares are powerful bursts of radiation. Harmful radiation from a flare cannot pass through Earth's atmosphere to physically affect humans on the ground, however -- when intense enough -- they can disturb the atmosphere in the layer where GPS and communications signals travel. To see how this event may affect Earth, please visit NOAA's Space Weather Prediction Center at spaceweather.gov, the U.S. government's official source for space weather forecasts, alerts, watches and warnings. This flare is classified as a M6.6 flare. M-class flares are a tenth the size of the most intense flares, the X-class flares. The number provides more information about its strength. An M2 is twice as intense as an M1, an M3 is three times as intense, etc. Credit: NASA/Goddard/SDO NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  15. Collision-induced rotation in an arc-continent collision: Constrained by continuous GPS observations in Mindoro, Philippines

    NASA Astrophysics Data System (ADS)

    Rau, R.; Hung, H.; Yang, C.; Tsai, M.; Ching, K.; Bacolcol, T.; Solidum, R.; Chang, W.

    2012-12-01

    The Mindoro Island, situated at the southern end of the Manila trench, is a modern arc-continent collision. Seismic activity in Mindoro concentrates mainly in the northern segment of the island as part of the Manila subduction processes; in contrast, seismicity in the middle and the southern parts of the island is rather diffuse. Although the Mindoro Island has been experiencing intense seismic activities and is a type example of arc-continent collision, the modern mode of deformation of the Mindoro collision remains unclear. We have installed eight dual-frequency continuous GPS stations in the island since May 2010. The questions we want to address by using continuous GPS observations are (1) if there are still compressions within the Mindoro collision? Have they ceased as seen by the diffuse seismicity, or are the thrust faults locked? (2) What is the mode of deformation in the Mindoro collision and what are the roles of thrust and strike-slip faults playing in the collision? (3) How does the Mindoro collision compare with the other collision, such as the Taiwan orogen? Do they share similar characteristics for the subduction-collision transition zone? For the results of the first two years GPS measurements, if we take the Sablayan site near the southern end of the Manila trench as the reference station, a large counterclockwise rotation from south to north, with horizontal velocities of 1.9-31.1 mm/yr from 165 to 277 degrees, are found in the island. The deformation of the Mindoro is similar to the pattern of the transition zone from collision to subduction in northeastern Taiwan. This result suggests that collision-induced rotation is occurring in the Mindoro Island and the Mindoro arc-continent collision is still active.

  16. Antibacterial activity and ion release of bonding agent containing amorphous calcium phosphate nanoparticles

    PubMed Central

    Chen, Chen; Weir, Michael D.; Cheng, Lei; Lin, Nancy; Lin-Gibson, Sheng; Chow, Laurence C.; Zhou, Xuedong; Xu, Hockin H. K.

    2015-01-01

    Objectives Recurrent caries at the margins is a primary reason for restoration failure. The objectives of this study were to develop bonding agent with the double benefits of antibacterial and remineralizing capabilities, to investigate the effects of NACP filler level and solution pH on Ca and P ion release from adhesive, and to examine the antibacterial and dentin bond properties. Methods Nanoparticles of amorphous calcium phosphate (NACP) and a quaternary ammonium monomer (dimethylaminododecyl methacrylate, DMADDM) were synthesized. Scotchbond Multi-Purpose (SBMP) primer and adhesive served as control. DMADDM was incorporated into primer and adhesive at 5% by mass. NACP was incorporated into adhesive at filler mass fractions of 10%, 20%, 30% and 40%. A dental plaque microcosm biofilm model was used to test the antibacterial bonding agents. Calcium (Ca) and phosphate (P) ion releases from the cured adhesive samples were measured vs. filler level and solution pH of 7, 5.5 and 4. Results Adding 5% DMADDM and 10–40% NACP into bonding agent, and water-aging for 28 days, did not affect dentin bond strength, compared to SBMP control at 1 day (p > 0.1). Adding DMADDM into bonding agent substantially decreased the biofilm metabolic activity and lactic acid production. Total microorganisms, total streptococci, and mutans streptococci were greatly reduced for bonding agents containing DMADDM. Increasing NACP filler level from 10% to 40% in adhesive increased the Ca and P ion release by an order of magnitude. Decreasing solution pH from 7 to 4 increased the ion release from adhesive by 6–10 folds. Significance Bonding agents containing antibacterial DMADDM and remineralizer NACP were formulated to have Ca and P ion release, which increased with NACP filler level from 10% to 40% in adhesive. NACP adhesive was “smart” and dramatically increased the ion release at cariogenic pH 4, when these ions would be most-needed to inhibit caries. Therefore, bonding agent

  17. Poly(amido amine) and calcium phosphate nanocomposite remineralization of dentin in acidic solution without calcium phosphate ions.

    PubMed

    Liang, Kunneng; Zhou, Han; Weir, Michael D; Bao, Chongyun; Reynolds, Mark A; Zhou, Xuedong; Li, Jiyao; Xu, Hockin H K

    2017-07-01

    Patients with dry mouth often have an acidic oral environment lacking saliva that provides calcium (Ca) and phosphate (P) ions. However, there has been no study on dentin remineralization by placing samples in an acidic solution without Ca and P ions. Previous studies used saliva-like solutions with neutral pH and Ca and P ions. Therefore, the objective of this study was to investigate a novel method of combining poly(amido amine) (PAMAM) with a composite of nanoparticles of amorphous calcium phosphate (NACP) on dentin remineralization in an acidic solution without Ca and P ions for the first time. Demineralized dentin specimens were tested into four groups: (1) dentin control, (2) dentin coated with PAMAM, (3) dentin with NACP nanocomposite, (4) dentin with PAMAM plus NACP composite. Specimens were treated with lactic acid at pH 4 without initial Ca and P ions for 21 days. Acid neutralization and Ca and P ion concentrations were measured. Dentin specimens were examined by scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and hardness testing vs. remineralization efficacy. NACP composite had mechanical properties similar to commercial control composites (p>0.1). NACP composite neutralized acid and released Ca and P ions. PAMAM alone failed to induce dentin remineralization. NACP alone achieved mild remineralization and slightly increased dentin hardness at 21days (p>0.1). In contrast, the PAMAM+NACP nanocomposite method in acid solution without initial Ca and P ions greatly remineralized the pre-demineralized dentin, restoring its hardness to approach that of healthy dentin (p>0.1). Dentin remineralization via PAMAM+NACP in pH 4 acid without initial Ca and P ions was demonstrated for the first time, when conventional methods such as PAMAM did not work. The novel PAMAM+NACP nanocomposite method is promising to protect tooth structures, especially for patients with reduced saliva to inhibit caries. Copyright © 2017 The Academy of Dental

  18. Dental plaque microcosm biofilm behavior on calcium phosphate nanocomposite with quaternary ammonium

    PubMed Central

    Cheng, Lei; Weir, Michael D.; Zhang, Ke; Wu, Eric; Xu, Sarah M.; Zhou, Xuedong; Xu, Hockin H. K.

    2012-01-01

    Objectives Half of dental restorations fail in 10 years, with secondary caries as the main reason. Calcium phosphate composites could remineralize tooth lesions. The objectives of this study were to: (1) Impart antibacterial activity to a composite with nanoparticles of amorphous calcium phosphate (NACP); and (2) investigate the effect of quaternary ammonium dimethacrylate (QADM) on mechanical and dental plaque microcosm biofilm properties for the first time. Methods The NACP and glass particles were filled into a dental resin that contained bis(2-methacryloyloxy-ethyl) dimethyl-ammonium bromide, the QADM. NACP nanocomposites containing 0%, 7%, 14%, and 17.5% of QADM by mass, respectively, were photo-cured. A commercial composite with no antibacterial activity was used as control. Mechanical properties were measured in three-point flexure. A human saliva microcosm model was used to grow biofilms on composites. Live/dead assay, metabolic activity, colony-forming unit (CFU) counts, and lactic acid production of biofilms on the composites were measured. Results Increasing QADM mass fraction monotonically reduced the biofilm viability, CFU and lactic acid. Biofilms on NACP nanocomposite with 17.5% QADM had metabolic activity that was 30% that on a commercial composite control (p<0.05). Total microorganisms, total streptococci, and mutans streptococci CFU counts (mean±sd; n=6) on composite control was 6-fold those on NACP+17.5% QADM nanocomposite. Composite control had long strings of cells with normal short-rod shapes, while some cells on NACP-QADM nanocomposites disintegrated into pieces. Adding QADM to NACP did not decrease the strength and elastic modulus, which matched (p>0.1) those of a commercial composite without Ca-PO4 or antibacterial activity. Significance A dental plaque microcosm model was used to evaluate the novel NACP-QADM nanocomposite. The nanocomposite greatly reduced the biofilm viability, metabolic activity and lactic acid, while its mechanical

  19. African Universities Tackle the Continent's Agricultural Crisis

    ERIC Educational Resources Information Center

    Lindow, Megan

    2009-01-01

    Pests, population growth, and depleted soil have wreaked havoc on agriculture in Africa, so universities across the continent are rethinking how they teach the topic. Some African universities have been building their own networks and pooling their limited resources to train more agricultural scientists and improve their responsiveness to the…

  20. Local and Remote Climate Response to Deforestation in Maritime Continent

    NASA Astrophysics Data System (ADS)

    Chen, C. C.; Lo, M. H.; Yu, J. Y.

    2016-12-01

    Deforestation in tropical regions would lead to changes in local energy and moisture budget, resulting in further impacts on regional and global climate. Previous studies have indicated that the reduction of evapotranspiration dominates the influence of tropical deforestation, which causes a warmer and drier climate. Most studies agree that the deforestation leads to an increase in temperature and decline in precipitation over the deforested area. However, unlike Amazon or Africa, Maritime Continent consists of islands surrounded by oceans so the drying effects found in Amazon or Africa may not be the case in Maritime Continent. Thus, our objective is to investigate the local and remote climate responses to deforestation in such unique region. We conduct deforestation experiments using NCAR Community Earth System Model (CESM) and through converting the tropical rainforest into grassland. The preliminary results show that deforestation in Maritime Continent leads to an increase in both temperature and precipitation, which is not predicted by earlier studies. We will further perform moisture budget analysis to explore how the precipitation changes with the deforestation forcing.

  1. Propagating convective system as a rainfall connection between southwestern Tibetan Plateau and Indian continent

    NASA Astrophysics Data System (ADS)

    Dong, W.; Lin, Y.; Xie, Y.

    2014-12-01

    The Tibetan Plateau (TP) is called "Asia's Water Tower" because it is the headwaters of many major rivers in Asia, upon which the production and living of nearly 1/6 world population strongly depends. Precipitation and its future change over the TP pose a large socio-economic impact on the surrounding nations. Using multiple precipitation datasets and CMIP5 model simulations, summer (June to September) precipitation over the TP and Indian continent is investigated. We note a close linkage of rainfall over the southwestern Tibetan Plateau (SWTP) and central-eastern India. Such a linkage is maintained by frequent propagation of convective systems from northern Indian lower lands over the high mountain range into SWTP. An objective propagation identification method suggests such propagation contributes nearly half of the total summer rainfall in SWTP. The propagation is prominent from late June to mid-September. Its occurrence is rather stable and appears not to be strongly modulated by Indian monsoon strength. The propagation also modifies the rainfall diurnal cycle with a second peak near midnight in addition to the late afternoon peak induced by localized convective systems. Favorable environmental conditions for propagations are also explored.

  2. Aerosol Meteorology of the Maritime Continent for the 2012 7SEAS Southwest Monsoon Intensive Study - Part 1: Regional-scale Phenomena

    NASA Technical Reports Server (NTRS)

    Reid, Jeffrey S.; Xian, Peng; Holben, Brent N.; Hyer, Edward J.; Reid, Elizabeth A.; Salinas, Santo V.; Zhang, Jianglong; Campbell, James R.; Chew, Boon Ning; Holz, Robert E.; hide

    2016-01-01

    The largest 7 Southeast Asian Studies (7SEAS) operation period within the Maritime Continent (MC) occurred in the August-September 2012 biomass burning season. Included was an enhanced deployment of Aerosol Robotic Network (AERONET) sun photometers, multiple lidars, and field measurements to observe transported smoke and pollution as it left the MC and entered the southwest monsoon trough. Here we describe the nature of the overall 2012 southwest monsoon (SWM) and biomass burning season to give context to the 2012 deployment. The MC in 2012 was in a slightly warm El Nino Southern Oscillation (ENSO) phase and with spatially typical burning activity. However, overall fire counts for 2012 were 10 lower than the Reid et al. (2012) baseline, with regions of significant departures from this norm, ranging from southern Sumatra (+30) to southern Kalimantan (42). Fire activity and monsoonal flows for the dominant burning regions were modulated by a series of intraseasonal oscillation events (e.g., Madden-Julian Oscillation, or MJO, and boreal summer intraseasonal oscillation, or BSISO). As is typical, fire activity systematically progressed eastward over time, starting with central Sumatran fire activity in June related to a moderately strong MJO event which brought drier air from the Indian Ocean aloft and enhanced monsoonal flow. Further burning in Sumatra and Kalimantan Borneo occurred in a series of significant events from early August to a peak in the first week of October, ending when the monsoon started to migrate back to its wintertime northeastern flow conditions in mid-October. Significant monsoonal enhancements and flow reversals collinear with tropical cyclone (TC) activity and easterly waves were also observed. Islands of the eastern MC, including Sulawesi, Java, and Timor, showed less sensitivity to monsoonal variation, with slowly increasing fire activity that also peaked in early October but lingered into November. Interestingly, even though fire counts were

  3. Aerosol meteorology of the Maritime Continent for the 2012 7SEAS southwest monsoon intensive study - Part 1: regional-scale phenomena

    NASA Astrophysics Data System (ADS)

    Reid, Jeffrey S.; Xian, Peng; Holben, Brent N.; Hyer, Edward J.; Reid, Elizabeth A.; Salinas, Santo V.; Zhang, Jianglong; Campbell, James R.; Chew, Boon Ning; Holz, Robert E.; Kuciauskas, Arunas P.; Lagrosas, Nofel; Posselt, Derek J.; Sampson, Charles R.; Walker, Annette L.; Welton, E. Judd; Zhang, Chidong

    2016-11-01

    The largest 7 Southeast Asian Studies (7SEAS) operation period within the Maritime Continent (MC) occurred in the August-September 2012 biomass burning season. Included was an enhanced deployment of Aerosol Robotic Network (AERONET) sun photometers, multiple lidars, and field measurements to observe transported smoke and pollution as it left the MC and entered the southwest monsoon trough. Here we describe the nature of the overall 2012 southwest monsoon (SWM) and biomass burning season to give context to the 2012 deployment. The MC in 2012 was in a slightly warm El Niño/Southern Oscillation (ENSO) phase and with spatially typical burning activity. However, overall fire counts for 2012 were 10 % lower than the Reid et al. (2012) baseline, with regions of significant departures from this norm, ranging from southern Sumatra (+30 %) to southern Kalimantan (-42 %). Fire activity and monsoonal flows for the dominant burning regions were modulated by a series of intraseasonal oscillation events (e.g., Madden-Julian Oscillation, or MJO, and boreal summer intraseasonal oscillation, or BSISO). As is typical, fire activity systematically progressed eastward over time, starting with central Sumatran fire activity in June related to a moderately strong MJO event which brought drier air from the Indian Ocean aloft and enhanced monsoonal flow. Further burning in Sumatra and Kalimantan Borneo occurred in a series of significant events from early August to a peak in the first week of October, ending when the monsoon started to migrate back to its wintertime northeastern flow conditions in mid-October. Significant monsoonal enhancements and flow reversals collinear with tropical cyclone (TC) activity and easterly waves were also observed. Islands of the eastern MC, including Sulawesi, Java, and Timor, showed less sensitivity to monsoonal variation, with slowly increasing fire activity that also peaked in early October but lingered into November. Interestingly, even though fire

  4. Left behind and left out: The impact of the school environment on young people with continence problems.

    PubMed

    Whale, Katie; Cramer, Helen; Joinson, Carol

    2018-05-01

    To explore the impact of the secondary school environment on young people with continence problems. In-depth qualitative semi-structured interviews. We interviewed 20 young people aged 11-19 years (11 female and nine male) with continence problems (daytime wetting, bedwetting, and/or soiling). Interviews were conducted by Skype (n = 11) and telephone (n = 9). Transcripts were analysed using inductive thematic analysis. We generated five main themes: (1) Boundaries of disclosure: friends and teachers; (2) Social consequences of avoidance and deceit; (3) Strict and oblivious gatekeepers; (4) Intimate actions in public spaces; and (5) Interrupted learning. Disclosure of continence problems at school to both friends and teachers was rare, due to the perceived stigma and fears of bullying and social isolation. The lack of disclosure to teachers and other school staff, such as pastoral care staff, creates challenges in how best to support these young people. Young people with continence problems require unrestricted access to private and adequate toilet facilities during the school day. There is a need for inclusive toilet access policies and improved toilet standards in schools. Addressing the challenges faced by young people with continence problems at school could help to remove the barriers to successful self-management of their symptoms. It is particularly concerning that young people with continence problems are at higher risk of academic underachievement. Increased support at school is needed to enable young people with continence problems to achieve their academic potential. Statement of Contribution What is already known on this subject? Continence problems are among the most common paediatric health problems Self-management of continence problems requires a structured schedule of fluid intake and bladder emptying Inadequate toilet facilities and restricted access make it difficult for young people to manage their incontinence What does this study add

  5. Effects of the intense geomagnetic storm of September-October 2012 on the equatorial, low- and mid-latitude F region in the American and African sector during the unusual 24th solar cycle

    NASA Astrophysics Data System (ADS)

    de Jesus, R.; Fagundes, P. R.; Coster, A.; Bolaji, O. S.; Sobral, J. H. A.; Batista, I. S.; de Abreu, A. J.; Venkatesh, K.; Gende, M.; Abalde, J. R.; Sumod, S. G.

    2016-02-01

    The main purpose of this paper is to investigate the response of the ionospheric F layer in the American and African sectors during the intense geomagnetic storm which occurred on 30 September-01 October 2012. In this work, we used observations from a chain of 20 GPS stations in the equatorial, low- and mid-latitude regions in the American and African sectors. Also, in this study ionospheric sounding data obtained during 29th September to 2nd October, 2012 at Jicamarca (JIC), Peru, São Luis (SL), Fortaleza (FZ), Brazil, and Port Stanley (PST), are presented. On the night of 30 September-01 October, in the main and recovery phase, the h´F variations showed an unusual uplifting of the F region at equatorial (JIC, SL and FZ) and mid- (PST) latitude stations related with the propagations of traveling ionospheric disturbances (TIDs) generated by Joule heating at auroral regions. On 30 September, the VTEC variations and foF2 observations at mid-latitude stations (American sector) showed a long-duration positive ionospheric storm (over 6 h of enhancement) associated with large-scale wind circulations and equatorward neutral winds. Also, on 01 October, a long-duration positive ionospheric storm was observed at equatorial, low- and mid- latitude stations in the African sector, related with the large-scale wind circulations and equatorward neutral winds. On 01 and 02 October, positive ionospheric storms were observed at equatorial, low- and mid-latitude stations in the American sector, possibly associated with the TIDs and an equatorward neutral wind. Also, on 01 October negative ionospheric storms were observed at equatorial, low- and mid-latitude regions in the American sector, probably associated with the changes in the O/N2 ratio. On the night of 30 September-01 October, ionospheric plasma bubbles were observed at equatorial, low- and mid- latitude stations in the South American sector, possibly associated with the occurrence of geomagnetic storm.

  6. Understanding Barriers to Continence Care in Institutions

    ERIC Educational Resources Information Center

    Tannenbaum, Cara; Labrecque, Danielle; Lepage, Christiane

    2005-01-01

    This work seeks to identify factors that facilitate or diminish care-providers' propensity to improve continence care in long-term care (LTC) settings. We conducted a cross-sectional qualitative study using focus group methodology in four long-term care institutions in Montreal, QC. Forty-two nurses, nursing assistants, and orderlies caring for…

  7. Convergence across a continent: adaptive diversification in a recent radiation of Australian lizards.

    PubMed

    Blom, Mozes P K; Horner, Paul; Moritz, Craig

    2016-06-15

    Recent radiations are important to evolutionary biologists, because they provide an opportunity to study the mechanisms that link micro- and macroevolution. The role of ecological speciation during adaptive radiation has been intensively studied, but radiations can arise from a diversity of evolutionary processes; in particular, on large continental landmasses where allopatric speciation might frequently precede ecological differentiation. It is therefore important to establish a phylogenetic and ecological framework for recent continental-scale radiations that are species-rich and ecologically diverse. Here, we use a genomic (approx. 1 200 loci, exon capture) approach to fit branch lengths on a summary-coalescent species tree and generate a time-calibrated phylogeny for a recent and ecologically diverse radiation of Australian scincid lizards; the genus Cryptoblepharus We then combine the phylogeny with a comprehensive phenotypic dataset for over 800 individuals across the 26 species, and use comparative methods to test whether habitat specialization can explain current patterns of phenotypic variation in ecologically relevant traits. We find significant differences in morphology between species that occur in distinct environments and convergence in ecomorphology with repeated habitat shifts across the continent. These results suggest that isolated analogous habitats have provided parallel ecological opportunity and have repeatedly promoted adaptive diversification. By contrast, speciation processes within the same habitat have resulted in distinct lineages with relatively limited morphological variation. Overall, our study illustrates how alternative diversification processes might have jointly stimulated species proliferation across the continent and generated a remarkably diverse group of Australian lizards. © 2016 The Author(s).

  8. Convergence across a continent: adaptive diversification in a recent radiation of Australian lizards

    PubMed Central

    Horner, Paul; Moritz, Craig

    2016-01-01

    Recent radiations are important to evolutionary biologists, because they provide an opportunity to study the mechanisms that link micro- and macroevolution. The role of ecological speciation during adaptive radiation has been intensively studied, but radiations can arise from a diversity of evolutionary processes; in particular, on large continental landmasses where allopatric speciation might frequently precede ecological differentiation. It is therefore important to establish a phylogenetic and ecological framework for recent continental-scale radiations that are species-rich and ecologically diverse. Here, we use a genomic (approx. 1 200 loci, exon capture) approach to fit branch lengths on a summary-coalescent species tree and generate a time-calibrated phylogeny for a recent and ecologically diverse radiation of Australian scincid lizards; the genus Cryptoblepharus. We then combine the phylogeny with a comprehensive phenotypic dataset for over 800 individuals across the 26 species, and use comparative methods to test whether habitat specialization can explain current patterns of phenotypic variation in ecologically relevant traits. We find significant differences in morphology between species that occur in distinct environments and convergence in ecomorphology with repeated habitat shifts across the continent. These results suggest that isolated analogous habitats have provided parallel ecological opportunity and have repeatedly promoted adaptive diversification. By contrast, speciation processes within the same habitat have resulted in distinct lineages with relatively limited morphological variation. Overall, our study illustrates how alternative diversification processes might have jointly stimulated species proliferation across the continent and generated a remarkably diverse group of Australian lizards. PMID:27306048

  9. Ecology of Australia: the effects of nutrient-poor soils and intense fires.

    PubMed

    Orians, Gordon H; Milewski, Antoni V

    2007-08-01

    Australia, the flattest, driest, and geologically oldest vegetated continent, has a uniquely high proportion of nutrient-poor soils. We develop a "Nutrient-Poverty/Intense-Fire Theory," which postulates that most anomalous features of organisms and ecosystems of Australia are the evolutionary consequences of adaptations to nutrient poverty, compounded by intense fire that tends to occur as a result of nutrient poverty. The fundamental tenet of the theory is that plants growing in environments with plentiful light and periodic adequate moisture, but on soils poor in phosphorus, zinc, and other indispensible nutrients, can synthesize carbohydrates in excess of the amount that can be combined with, or catalyzed by, these nutrients for metabolism and production of nutrient-rich foliage and reproductive tissues. They use this "expendable energy" to produce well-defended foliage, large quantities of lignified tissues, and readily digestible exudates. Rapid accumulation of nutrient-poor biomass, a result of low rates of herbivory, provides fuel for intense fire. Intense fire exacerbates nutrient poverty by volatilizing certain micronutrients critical for animals. Anomalous features of organisms of Australia that can be explained by this theory, rather than by climate or phylogenetic history alone, include the following: most woody plants have long-lived, durable foliage; plants defend their tissues primarily with carbon-rich but nutrient-poor compounds; an unusually high proportion of plants protects seeds from fire and granivores in sturdy, woody capsules or follicles; plants allocate unusually large amounts of expendable energy to production of carbon-based exudates, such as nectar and gums; an unusually high proportion of plant species is pollinated by vertebrates that average larger size than pollinators on other continents; herbivores are small and have slow metabolism; there are no ruminants, mammals that eat mainly subterranean plant matter, or fungus

  10. A Continued Census of Mid-IR Variability from ULXs

    NASA Astrophysics Data System (ADS)

    Lau, Ryan; Kasliwal, Mansi; Heida, Marianne; Walton, Dom

    2017-04-01

    The nature of ultraluminous X-ray sources (ULXs) that radiate at luminosities >10^39 erg/s is still a mystery. ULXs are believed to be binaries with an accreting compact object and stellar mass-donor companion, but such high luminosities require accretion rates that are factors of 100 greater than the Eddington limit for accretion onto a neutron star or stellar mass black hole. The difficulties in interpreting ULXs are largely attributed to current observational challenges in determining their orbital properties as well as the properties of the mass-donor companion. Recently, near- and mid-infrared (IR) observations have been demonstrated as powerful diagnostics of the mass-donor companion and the circumstellar environment of ULXs. For example, serendipitous Spitzer/IRAC observations of the ULX Holmberg II X-1 in our Spitzer Infrared Intensive Transients Survey (SPIRITS) revealed the first detection of mid-IR variability from a ULX, where we claimed that the mid-IR emission arises from a dusty circumbinary torus in the winds of a supergiant B[e] mass-donor companion. We identified 5 additional mid-IR ULX counterparts detected by Spitzer/IRAC, one of which shows significant variability like Holmberg II X-1. Although we are finding a growing sample of ULXs exhibiting mid-IR variability, it is unclear what causes it. Notably, the week - year cadence baselines of the SPIRITS observations are inadequate for resolving variability timescales consistent with several observed ULX orbital periods. In this proposal, we request time-series observations of 6 ULXs with cadence baselines ranging from 0.5 days to 1 week in order to identify the timescales associated mid-IR variability.

  11. Mantle temperature under drifting deformable continents during the supercontinent cycle

    NASA Astrophysics Data System (ADS)

    Yoshida, Masaki

    2013-04-01

    The thermal heterogeneity of the Earth's mantle under the drifting continents during a supercontinent cycle is a controversial issue in earth science. Here, a series of numerical simulations of mantle convection are performed in 3D spherical-shell geometry, incorporating drifting deformable continents and self-consistent plate tectonics, to evaluate the subcontinental mantle temperature during a supercontinent cycle. Results show that the laterally averaged temperature anomaly of the subcontinental mantle remains within several tens of degrees (±50 °C) throughout the simulation time. Even after the formation of the supercontinent and the development of subcontinental plumes due to the subduction of the oceanic plates, the laterally averaged temperature anomaly of the deep mantle under the continent is within +10 °C. This implies that there is no substantial temperature difference between the subcontinental and suboceanic mantles during a supercontinent cycle. The temperature anomaly immediately beneath the supercontinent is generally positive owing to the thermal insulation effect and the active upwelling plumes from the core-mantle boundary. In the present simulation, the formation of a supercontinent causes the laterally averaged subcontinental temperature to increase by a maximum of 50 °C, which would produce sufficient tensional force to break up the supercontinent. The periodic assembly and dispersal of continental fragments, referred to as the supercontinent cycle, bear close relation to the evolution of mantle convection and plate tectonics. Supercontinent formation involves complex processes of introversion, extroversion or a combination of these in uniting dispersed continental fragments, as against the simple opening and closing of individual oceans envisaged in Wilson cycle. In the present study, I evaluate supercontinent processes in a realistic mantle convection regime. Results show that the assembly of supercontinents is accompanied by a

  12. Fluid Percolation Within AN Ocean-Continent Transition

    NASA Astrophysics Data System (ADS)

    Kaczmarek, M.; Reddy, S. M.

    2013-12-01

    Divergent plate boundaries, such as ocean-continent transitions (OCT) are the perfect target to study mechanisms activated during extension leading to localisation of deformation. The Platta-Totalp massifs in the Eastern Central Alps (Grison, Switzerland) represent a type example of a zone of exhumed continental mantle and offer a complete stratigraphic sequence of an OCT. A detailed study of the geochemistry and microstructures is undertaken to characterise the deformation in such setting. The mantle rocks are spinel lherzolites and harzburgites, into which gabbros and basaltic dykes were intruded, and are partially covered by ophicarbonates. Previous work across the Platta reveals that mantle rocks close to the continent may represent spinel peridotite mixed with (garnet)-pyroxenite layers while the ultramafic rocks at some distance from the continent are pyroxenite-poor peridotites that equilibrated in the plagioclase stability field (Muntener et al. 2004). Fieldwork across the mantle sequence shows localization of deformation with metric or centimetric shear-zones. Peridotites in shear-zones close to the continent have an ultra-mylonitic texture, and contain amphibole testifying fluid percolation. In a centimetric shear-zone amphibole is observed within a matrix made up of a mixture of pyroxenes, olivine, amphibole and spinel with a grain size from 1 to 8 μm, and as round grains (grain size from 30 to 50μm) embedded in the fine-grained matrix. The host peridotite, which is also deformed, contains larger grains of amphibole with a grain size up to 400 μm. The chemical composition of the amphibole changes from large to small grains, increasing in K2O and decreasing in TiO2 (wt%) indicating an evolution of the percolating fluid during the localisation of deformation. Another ultra-mylonite (grain size ~ 5μm) from the same mantle sequence displays unmixed areas of clinopyroxene-amphibole and olivine-orthopyroxene, which are folded together. The chemical

  13. [Functional anatomy of the male continence mechanism].

    PubMed

    Schwalenberg, T; Neuhaus, J; Dartsch, M; Weissenfels, P; Löffler, S; Stolzenburg, J-U

    2010-04-01

    The basic structures and organs contributing to continence in men are far less well investigated than in women. This concerns anatomical and functional aspects as well. Especially the cooperation of single components and the dynamic anchoring in the pelvic floor require further investigation. An improved anatomical-functional interpretation is needed to generate therapeutic concepts orientated at the physiology of the bladder neck.Therefore, the focus of anatomical investigations should be on the external sphincter which is the main muscle responsible for urethral closure as well as on the connective tissue, smooth muscular and neuronal structures in the pelvis. The smooth muscular structures involved are the internal sphincter, the inner parts of the external sphincter, the urethral longitudinal musculature, and parts of the centrum perinei and of the ventral suspension apparatus which fixes the position of the bladder neck and seems to be vital for continence and initiation of micturition. These new findings imply an integral concept for men as was developed for women. A first step in this regard would be a consistent and updated anatomical nomenclature.

  14. Madagascar: Heads It's a Continent, Tails It's an Island

    NASA Astrophysics Data System (ADS)

    de Wit, Maarten J.

    Neither geologists nor biologists have a definition that is capable of classifying Madagascar unambiguously as an island or a continent; nor can they incorporate Malagasy natural history into a single model rooted in Africa or Asia. Madagascar is a microcosm of the larger continents, with a rock record that spans more than 3000 million years (Ma), during which it has been united episodically with, and divorced from, Asian and African connections. This is reflected in its Precambrian history of deep crustal tectonics and a Phanerozoic history of biodiversity that fluctuated between cosmopolitanism and parochialism. Both vicariance and dispersal events over the past 90 Ma have blended a unique endemism on Madagascar, now in decline following rapid extinctions that started about 2000 years ago.

  15. Family Planning in Five Continents: Africa, America, Asia, Europe, Oceania. December 1976 Update.

    ERIC Educational Resources Information Center

    International Planned Parenthood Federation, London (England).

    This document gives highlights of the family planning situation in many countries of the world. Its purpose is to provide a quick reference source for those who work in family planning. Population statistics are included for five continents and many countries. Data for the continents include population in 1976, projected population in 2000,…

  16. Modelling the mid-infrared drying of sweet potato: kinetics, mass and heat transfer parameters, and energy consumption

    NASA Astrophysics Data System (ADS)

    Onwude, Daniel I.; Hashim, Norhashila; Abdan, Khalina; Janius, Rimfiel; Chen, Guangnan

    2018-04-01

    This study investigated the drying kinetics, mass and heat transfer characteristics of sweet potato slices (0.4-0.6 cm thickness) during drying based on mid-infrared experimental set-up (intensity of 1100-1400 W/m2). Thin layer drying models were used to evaluate the drying kinetics of sweet potato slices. Two analytical models (Fick's diffusion model, and Dincer and Dost model) were used to study the mass transfer behaviour of sweet potato slices with and without shrinkage during mid-infrared drying. The heat transfer flux between the emitter and sweet potato slices was also investigated. Results demonstrated that an increase in infrared intensity from 1100 W/m2 to 1400 W/m2 resulted in increased in average radiation heat flux by 3.4 times and a 15% reduction in the overall drying time. The two-term exponential model was found to be the best in predicting the drying kinetics of sweet potato slices during mid-infrared drying. The specific heat consumption varied from 0.91-4.82 kWh/kg. The effective moisture diffusivity with and without shrinkage using the Fick's diffusion model varied from 2.632 × 10-9 to 1.596 × 10-8 m2/s, and 1.24 × 10-8 to 2.4 × 10-8 m2/s using Dincer and Dost model, respectively. The obtained values of mass transfer coefficient, Biot number and activation energy varied from 5.99 × 10-6 to 1.17 × 10-5 m/s, 0.53 to 2.62, and 12.83 kJ/mol to 34.64 kJ/mol, respectively. The values obtained for Biot number implied the existence of simultaneous internal and external resistances. The findings further explained that mid-infrared intensity of 1100 W/m2 did not significantly affect the quality of sweet potato during drying, demonstrating a great potential of applying low intensity mid-infrared radiation in the drying of agricultural crops.

  17. Recent Aeromagnetic Anomaly views of the Antarctic continent

    NASA Astrophysics Data System (ADS)

    Ferraccioli, F.

    2012-04-01

    Antarctica is a keystone within the Gondwana and Rodinia supercontinents. However, despite intense geological research along the coastal fringes of Antarctica, the interior of the continent remains one of the most poorly understood regions on Earth. Aeromagnetic investigations are a useful tool to help disclose the structure and the evolution of continents from the Precambrian to the Cenozoic and Antarctica is no exception. Here I review a variety of aeromagnetic studies in East and West Antarctica performed since the completion of the first generation ADMAP -Antarctic Digital Magnetic Anomaly Project- in 2001. In western Dronning Maud, in East Antarctica, aeromagnetic data help delineate the extent of the Jurassic Jutulstraumen subglacial rift that is flanked by remnants of a Grenvillian-age (ca 1.1. Ga) igneous province and magmatic arc. Different magnetic signatures appear to characterize the Coats Land block but reconnaissance surveys are insufficient to fully delineate the extent and significance of the Coats Land block, a possible tectonic tracer of Laurentia within Rodinia (Loewy et al., 2011). Further in the interior of East Antarctica, a mosaic of distinct and hitherto largely unknown Precambrian provinces has recently been revealed by combining aeromagnetic and satellite magnetic data with models of crustal thickness constrained by gravity modeling and seismology (Ferraccioli et al., 2011, Nature). A major collisional suture may lie between the Archean Ruker Province and an inferred Proterozoic Gamburtsev Province but the age of final assembly of central East Antarctica remains uncertain and controversial. I favour a Grenville-age collisional event (linked to Rodinia assembly) or possibly older Paleoproteroic collision, followed by intraplate reactivation, as opposed to Neoproterozoic or Early Cambrian collision linked to East-West Gondwana assembly (Boger, 2011). New aerogeophysical surveys over Prince Elizabeth and Queen Mary Land could test this

  18. Efficiency of using community organisations as catalysts for recruitment to continence promotion trials.

    PubMed

    Agnew, Rona; van den Heuvel, Eleanor; Tannenbaum, Cara

    2013-02-01

    A major challenge for determining the effectiveness of community-based continence promotion campaigns is recruitment of a representative sample of incontinent participants who have not previously sought care. To evaluate the efficiency of engaging community organisations as catalysts for recruitment of community-dwelling older women with incontinence to the 'Continence across Continents' randomised controlled trial. Seniors' and women's community-based organisations throughout the United Kingdom were solicited by telephone or email to assist recruitment for an open-label cluster randomised controlled trial testing three experimental continence promotion interventions and a control intervention for incontinent older women. Women aged 60 years and older who experienced at least weekly urinary incontinence and who had never sought treatment were eligible to participate. The response rate of the organisations and enrolment rate of eligible participants attending the continence promotion workshops were recorded. Differences in recruitment efficiency by intervention group were ascertained using analysis of variance statistics. We contacted 408 community organisations over a 1-year period. Seventy organisations (17%) agreed to host a workshop, 249 (61%) did not provide a response, and 89 (22%) refused. Workshops were administered in a group format to 61 organisations (15%); 667 women attended, 583 (87%) submitted the screening questionnaire, and 437 (66%) met eligibility criteria for inclusion. A total of 192 women consented to participate in the trial, yielding a 44% recruitment efficiency among workshop attendees known to be eligible, with no significant difference in enrolment rates between groups. However, the mean participant recruitment rate per number of attendees at each workshop was only 29%, varying substantially between groups from 19% to 37%, with the lowest rate observed for the control group. The mean annual recruitment rate expressed as the number of

  19. Effect of spinal anaesthesia on the lower urinary tract in continent women.

    PubMed

    Haeusler, G; Sam, C; Chiari, A; Tempfer, C; Hanzal, E; Koelbl, H

    1998-01-01

    To evaluate the effect of spinal anaesthesia on the bladder neck position and the urethral closure function in the resting state and during clinical stress test in healthy, continent women. Controlled clinical trial. Department of Gynaecology and Obstetrics, Vienna University Medical School. Fourteen continent women, of which seven were nulliparous and seven parous, underwent minor gynaecological procedures under spinal anaesthesia. Urodynamics and ultrasound investigations were performed before and during spinal anaesthesia. Changes in the bladder neck position and the urethral closure function before and during spinal anaesthesia. Bladder neck position was found to be lower and more posterior during spinal anaesthesia as compared with pre-operative assessment. The posterior urethrovesical angle increased significantly both at rest and during maximum straining. We observed a significant increase in bladder compliance, and all parameters of the urethral pressure profile decreased significantly. While none of the nulliparous women had a positive clinical stress test during spinal anaesthesia, 4/7 parous women demonstrated leakage (Fisher's exact test, P = 0.003). Blockage of nerve supply to the pelvic floor muscles in continent women is associated with a significant loss of support of the bladder neck region confirming the theory of an active mechanism of muscular elements providing continence.

  20. Elastomeric microparticles for acoustic mediated bioseparations

    PubMed Central

    2013-01-01

    Background Acoustophoresis has been utilized successfully in applications including cell trapping, focusing, and purification. One current limitation of acoustophoresis for cell sorting is the reliance on the inherent physical properties of cells (e.g., compressibility, density) instead of selecting cells based upon biologically relevant surface-presenting antigens. Introducing an acoustophoretic cell sorting approach that allows biochemical specificity may overcome this limitation, thus advancing the value of acoustophoresis approaches for both the basic research and clinical fields. Results The results presented herein demonstrate the ability for negative acoustic contrast particles (NACPs) to specifically capture and transport positive acoustic contrast particles (PACPs) to the antinode of an ultrasound standing wave. Emulsification and post curing of pre-polymers, either polydimethylsiloxane (PDMS) or polyvinylmethylsiloxane (PVMS), within aqueous surfactant solution results in the formation of stable NACPs that focus onto pressure antinodes. We used either photochemical reactions with biotin-tetrafluorophenyl azide (biotin-TFPA) or end-functionalization of Pluronic F108 surfactant to biofunctionalize NACPs. These biotinylated NACPs bind specifically to streptavidin polystyrene microparticles (as cell surrogates) and transport them to the pressure antinode within an acoustofluidic chip. Conclusion To the best of our knowledge, this is the first demonstration of using NACPs as carriers for transport of PACPs in an ultrasound standing wave. By using different silicones (i.e., PDMS, PVMS) and curing chemistries, we demonstrate versatility of silicone materials for NACPs and advance the understanding of useful approaches for preparing NACPs. This bioseparation scheme holds potential for applications requiring rapid, continuous separations such as sorting and analysis of cells and biomolecules. PMID:23809852

  1. Intense 2.7 μm mid-infrared emission of Er{sup 3+} in oxyfluoride glass ceramic containing NaYF{sub 4} nanocrystals

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Yin; Liu, Xueyun; Wang, Weichao

    2016-04-15

    Highlights: • Transparent oxyfluoride glass-ceramics containing NaYF{sub 4}:Er{sup 3+} nanocrystals have been prepared. • Intense 2.7 μm emission of the glass-ceramics has been demonstrated. • Prolonged decay lifetimes of Er{sup 3+}:{sup 4}I{sub 11/2} and {sup 4}I{sub 13/2} levels have been achieved. - Abstract: Transparent oxyfluoride glass ceramics containing NaYF{sub 4}:Er{sup 3+} nanocrystals have been prepared by melt quenching and subsequent thermal treatment. X-ray diffraction and high-resolution transmission electron microscopy analysis confirmed the precipitation of NaYF{sub 4} nanocrystals in glass. Energy dispersive spectrometer results evidenced the preferential concentration of Er{sup 3+} ions in nanocrystals. Mid-infrared, upconversion, and near-infrared emissions were measuredmore » upon excitation with 980 nm laser diode and the luminescence mechanisms were discussed. Intense 2.7 μm emission originating from the Er{sup 3+}:{sup 4}I{sub 11/2} → {sup 4}I{sub 13/2} transition was achieved due to the incorporation of Er{sup 3+} ions into the precipitated low phonon energy fluoride nanocrystals. The results indicate that oxyfluoride glass ceramic containing NaYF{sub 4}:Er{sup 3+} nanocrystals is a promising candidate material for 2.7 μm laser.« less

  2. Study on the mechanism of human blood glucose concentration measuring using mid-infrared spectral analysis technology

    NASA Astrophysics Data System (ADS)

    Li, Xiang

    2016-10-01

    All forms of diabetes increase the risk of long-term complications. Blood glucose monitoring is of great importance for controlling diabetes procedure, preventing the complications and improving the patient's life quality. At present, the clinical blood glucose concentration measurement is invasive and could be replaced by noninvasive spectroscopy analytical techniques. The mid-infrared spectral region contains strong characteristic and well-defined absorption bands. Therefore, mid-infrared provides an opportunity for monitoring blood glucose invasively with only a few discrete bonds. Although the blood glucose concentration measurement using mid-infrared spectroscopy has a lot of advantages, the disadvantage is also obvious. The absorption in this infrared region is fundamental molecular group vibration. Absorption intensity is very strong, especially for biological molecules. In this paper, it figures out that the osmosis rate of glucose has a certain relationship with the blood glucose concentration. Therefore, blood glucose concentration could be measured indirectly by measuring the glucose exudate in epidermis layer. Human oral glucose tolerance tests were carried out to verify the correlation of glucose exudation in shallow layer of epidermis layer and blood glucose concentration. As it has been explained above, the mid-infrared spectral region contains well-defined absorption bands, the intensity of absorption peak around 1123 cm-1 was selected to measure the glucose and that around 1170 cm-1 was selected as reference. Ratio of absorption peak intensity was recorded for each set of measurement. The effect and importance of the cleaning the finger to be measured before spectrum measuring are discussed and also verified by experiment.

  3. Performance of mid infrared spectroscopy in skin cancer cell type identification

    NASA Astrophysics Data System (ADS)

    Kastl, Lena; Kemper, Björn; Lloyd, Gavin R.; Nallala, Jayakrupakar; Stone, Nick; Naranjo, Valery; Penaranda, Francisco; Schnekenburger, Jürgen

    2017-02-01

    Marker free optical spectroscopy is a powerful tool for the rapid inspection of pathologically suspicious skin lesions and the non-invasive detection of early skin tumors. This goal can be reached by the combination of signal localization and the spectroscopical detection of chemical cell signatures. We here present the development and application of mid infrared spectroscopy (midIR) for the analysis of skin tumor cell types and three dimensional tissue phantoms towards the application of midIR spectroscopy for fast and reliable skin diagnostics. We developed standardized in vitro skin systems with increasing complexity, from single skin cell types as fibroblasts, keratinocytes and melanoma cells, to mixtures of these and finally three dimensional skin cancer phantoms. The cell systems were characterized with different systems in the midIR range up to 12 μm. The analysis of the spectra by novel data processing algorithms demonstrated the clear separation of all cell types, especially melanoma cells. Special attention and algorithm training was required for closely related mesenchymal cell types as dedifferentiated melanoma cells and fibroblasts. Proof of concept experiments with mixtures of in vivo fluorescence labelled skin cell types allowed the test of the new algorithms performance for the identification of specific cell types. The intense training of the software systems with various samples resulted in a increased sensitivity and specificity of the combined midIR and software system. These data highlight the potential of midIR spectroscopy as sensitive and specific future optical biopsy technology.

  4. Pentraxin-3 Predicts Short- and Mid-term Mortality in Patients with Sepsis and Septic Shock During Intensive Care Treatment.

    PubMed

    Hamed, Sonja; Behnes, Michael; Pauly, Dominic; Lepiorz, Dominic; Barre, Max; Becher, Tobias; Lang, Siegfried; Akin, Ibrahim; Borggrefe, Martin; Bertsch, Thomas; Hoffmann, Ursula

    2018-06-01

    The prognostic value of the acute phase protein Pentraxin 3 (PTX-3) is not well evaluated in patients with septic shock, which reveal an unacceptably high short- and long-term mortality. New Sepsis-3 definitions are not yet implemented in most biomarker studies. Therefore, this study assesses the prognostic value of PTX-3 for short- and mid-term mortality in patients with sepsis or septic shock, as defined by the latest definitions, treated at a medical intensive care unit (ICU). The study includes 213 ICU patients with clinical criteria of sepsis and septic shock. Plasma levels of PTX-3, procalcitonin (PCT) and interleukin-6 were measured on day 1, 3, and 8. All-cause mortality was followed up to 30 days and at 6 months. On all three days, PTX-3 levels were able to discriminate non-survivors from survivors at 30 days and 6 months (AUC range: 0.59 - 0.70; 95% CI: 0.52 - 0.79; p ≤ 0.02). Highest PTX-3 levels within the fourth quartiles during the first week of ICU treatment were associated with an increased mortality rate at 30 days (OR = 7; 95% CI: 2.0 - 23.5; p ≤ 0.002) and at 6 months (OR = 5; 95% CI: 2.1 - 11.4; p ≤ 0.006). Additionally, the prognostic value of PTX-3 was proven for all patients as well as in subcohorts of patients with sepsis and septic shock, according to Sepsis-3 criteria, both in univariate and multivariate analyses for 30-day and 6-months all-cause mortality, especially predicting all-cause mortality in septic shock (HRs range: 1.0 - 2.9; 95% CI: 0.3 - 5.1; p ≤ 0.03). PTX-3 offers prognostic value for the prediction of short- and mid-term all-cause mortality in patients suffering from sepsis and septic shock according to the latest Sepsis-3 criteria.

  5. Fear and overprotection in Australian residential aged-care facilities: The inadvertent impact of regulation on quality continence care.

    PubMed

    Ostaszkiewicz, Joan; O'Connell, Beverly; Dunning, Trisha

    2016-06-01

    Most residents in residential aged-care facilities are incontinent. This study explored how continence care was provided in residential aged-care facilities, and describes a subset of data about staffs' beliefs and experiences of the quality framework and the funding model on residents' continence care. Using grounded theory methodology, 18 residential aged-care staff members were interviewed and 88 hours of field observations conducted in two facilities. Data were analysed using a combination of inductive and deductive analytic procedures. Staffs' beliefs and experiences about the requirements of the quality framework and the funding model fostered a climate of fear and risk adversity that had multiple unintended effects on residents' continence care, incentivising dependence on continence management, and equating effective continence care with effective pad use. There is a need to rethink the quality of continence care and its measurement in Australian residential aged-care facilities. © 2015 AJA Inc.

  6. Antibacterial activity and ion release of bonding agent containing amorphous calcium phosphate nanoparticles.

    PubMed

    Chen, Chen; Weir, Michael D; Cheng, Lei; Lin, Nancy J; Lin-Gibson, Sheng; Chow, Laurence C; Zhou, Xuedong; Xu, Hockin H K

    2014-08-01

    Recurrent caries at the margins is a primary reason for restoration failure. The objectives of this study were to develop bonding agent with the double benefits of antibacterial and remineralizing capabilities, to investigate the effects of NACP filler level and solution pH on Ca and P ion release from adhesive, and to examine the antibacterial and dentin bond properties. Nanoparticles of amorphous calcium phosphate (NACP) and a quaternary ammonium monomer (dimethylaminododecyl methacrylate, DMADDM) were synthesized. Scotchbond Multi-Purpose (SBMP) primer and adhesive served as control. DMADDM was incorporated into primer and adhesive at 5% by mass. NACP was incorporated into adhesive at filler mass fractions of 10%, 20%, 30% and 40%. A dental plaque microcosm biofilm model was used to test the antibacterial bonding agents. Calcium (Ca) and phosphate (P) ion releases from the cured adhesive samples were measured vs. filler level and solution pH of 7, 5.5 and 4. Adding 5% DMADDM and 10-40% NACP into bonding agent, and water-aging for 28 days, did not affect dentin bond strength, compared to SBMP control at 1 day (p>0.1). Adding DMADDM into bonding agent substantially decreased the biofilm metabolic activity and lactic acid production. Total microorganisms, total streptococci, and mutans streptococci were greatly reduced for bonding agents containing DMADDM. Increasing NACP filler level from 10% to 40% in adhesive increased the Ca and P ion release by an order of magnitude. Decreasing solution pH from 7 to 4 increased the ion release from adhesive by 6-10 folds. Bonding agents containing antibacterial DMADDM and remineralizer NACP were formulated to have Ca and P ion release, which increased with NACP filler level from 10% to 40% in adhesive. NACP adhesive was "smart" and dramatically increased the ion release at cariogenic pH 4, when these ions would be most-needed to inhibit caries. Therefore, bonding agent containing DMADDM and NACP may be promising to inhibit

  7. Dental plaque microcosm biofilm behavior on calcium phosphate nanocomposite with quaternary ammonium.

    PubMed

    Cheng, Lei; Weir, Michael D; Zhang, Ke; Wu, Eric J; Xu, Sarah M; Zhou, Xuedong; Xu, Hockin H K

    2012-08-01

    Half of dental restorations fail in 10 years, with secondary caries as the main reason. Calcium phosphate composites could remineralize tooth lesions. The objectives of this study were to: (1) impart antibacterial activity to a composite with nanoparticles of amorphous calcium phosphate (NACP); and (2) investigate the effect of quaternary ammonium dimethacrylate (QADM) on mechanical and dental plaque microcosm biofilm properties for the first time. The NACP and glass particles were filled into a dental resin that contained bis(2-methacryloyloxy-ethyl) dimethyl-ammonium bromide, the QADM. NACP nanocomposites containing 0%, 7%, 14%, and 17.5% of QADM by mass, respectively, were photo-cured. A commercial composite with no antibacterial activity was used as control. Mechanical properties were measured in three-point flexure. A human saliva microcosm model was used to grow biofilms on composites. Live/dead assay, metabolic activity, colony-forming unit (CFU) counts, and lactic acid production of biofilms on the composites were measured. Increasing QADM mass fraction monotonically reduced the biofilm viability, CFU and lactic acid. Biofilms on NACP nanocomposite with 17.5% QADM had metabolic activity that was 30% that on a commercial composite control (p<0.05). Total microorganisms, total streptococci, and mutans streptococci CFU counts (mean ± sd; n = 6) on composite control was 6-fold those on NACP +17.5% QADM nanocomposite. Composite control had long strings of bacterial cells with normal short-rod shapes, while some cells on NACP-QADM nanocomposites disintegrated into pieces. Adding QADM to NACP did not decrease the composite strength and elastic modulus, which matched (p>0.1) those of a commercial composite without Ca-PO(4) or antibacterial activity. A dental plaque microcosm model was used to evaluate the novel NACP-QADM nanocomposite. The nanocomposite greatly reduced the biofilm viability, metabolic activity and lactic acid, while its mechanical properties

  8. Anorectal function in patients with complete rectal prolapse. Differences between continent and incontinent individuals.

    PubMed

    Roig, J V; Buch, E; Alós, R; Solana, A; Fernández, C; Villoslada, C; García-Armengol, J; Hinojosa, J

    1998-11-01

    A study is made of the alterations in anorectal physiology among rectal prolapse patients, evaluating the differences between fecal continent and incontinent individuals. Eighteen patients with complete rectal prolapse were divided into two groups: Group A (8 continent individuals) and Group B (10 incontinent women), while 22 healthy women were used as controls (Group C). Clinical exploration and perineal level measurements were performed, along with anorectal manometry, electrophysiology, and anorectal sensitivity to electrical stimuli. The main antecedents of the continent subjects were excess straining efforts, while the incontinent women presented excess straining and complex deliveries. Pathological perineal descent was a frequent finding in both groups, with a hypotonic anal canal at rest (p < 0.001 vs controls) and at voluntary squeezing (p < 0.001 vs controls). In turn, the incontinent patients exhibited a significantly lower anal canal pressure at rest than the continent women (p < 0.05). There were no significant differences between Groups A and C in terms of pudendal motor latency, though latency was significantly longer in Group B than in the controls (p < 0.01). Moreover, pudendal neuropathy was more common, severe and often bilateral in Group B. There were no differences in rectal sensation to distention or in terms of the volumes required to relax the internal anal sphincter. In turn, both prolapse groups exhibited diminished anal canal and rectal sensitivity to electrical stimuli. Patients with rectal prolapse exhibit a hypotonic anal canal at rest, regardless of whether they are continent to feces or not. Continent patients have less pudendal neuropathy and therefore less pressure alterations at voluntary sphincter squeeze than incontinent individuals.

  9. Self-consistent formation of continents on early Earth

    NASA Astrophysics Data System (ADS)

    Noack, Lena; Van Hoolst, Tim; Breuer, Doris; Dehant, Véronique

    2013-04-01

    In our study we want to understand how Earth evolved with time and examine the initiation of plate tectonics and the possible formation of continents on Earth. Plate tectonics and continents seem to influence the likelihood of a planet to harbour life [1], and both are strongly influenced by the planetary interior (e.g. mantle temperature and rheology) and surface conditions (e.g. stabilizing effect of continents, atmospheric temperature), and may also depend on the biosphere. Earth is the only terrestrial planet (i.e. with a rocky mantle and iron core) in the solar system where long-term plate tectonics evolved. Knowing the factors that have a strong influence on the occurrence of plate tectonics allows for prognoses about plate tectonics on terrestrial exoplanets that have been detected in the past decade, and about the likelihood of these planets to harbour Earth-like life. For this purpose, planetary interior and surface processes are coupled via 'particles' as computational tracers in the 3D code GAIA [2,3]. These particles are dispersed in the mantle and crust of the modelled planet and can track the relevant rock properties (e.g. density or water content) over time. During the thermal evolution of the planet, the particles are advected due to mantle convection and along melt paths towards the surface and help to gain information about the thermo-chemical system. This way basaltic crust that is subducted into the silicate mantle is traced in our model. It is treated differently than mantle silicates when re-molten, such that granitic (felsic) crust is produced (similar to the evolution of continental crust on early Earth [4]), which is stored in the particle properties. We apply a pseudo-plastic rheology and use small friction coefficients (since an increased reference viscosity is used in our model). We obtain initiation of plate tectonics and self-consistent formation of pre-continents after a few Myr up to several Gyr - depending on the initial conditions

  10. Global Mapping of Oceanic and Continental Shelf Crustal Thickness and Ocean-Continent Transition Structure

    NASA Astrophysics Data System (ADS)

    Kusznir, Nick; Alvey, Andy; Roberts, Alan

    2017-04-01

    The 3D mapping of crustal thickness for continental shelves and oceanic crust, and the determination of ocean-continent transition (OCT) structure and continent-ocean boundary (COB) location, represents a substantial challenge. Geophysical inversion of satellite derived free-air gravity anomaly data incorporating a lithosphere thermal anomaly correction (Chappell & Kusznir, 2008) now provides a useful and reliable methodology for mapping crustal thickness in the marine domain. Using this we have produced the first comprehensive maps of global crustal thickness for oceanic and continental shelf regions. Maps of crustal thickness and continental lithosphere thinning factor from gravity inversion may be used to determine the distribution of oceanic lithosphere, micro-continents and oceanic plateaux including for the inaccessible polar regions (e.g. Arctic Ocean, Alvey et al.,2008). The gravity inversion method provides a prediction of continent-ocean boundary location which is independent of ocean magnetic anomaly and isochron interpretation. Using crustal thickness and continental lithosphere thinning factor maps with superimposed shaded-relief free-air gravity anomaly, we can improve the determination of pre-breakup rifted margin conjugacy and sea-floor spreading trajectory during ocean basin formation. By restoring crustal thickness & continental lithosphere thinning to their initial post-breakup configuration we show the geometry and segmentation of the rifted continental margins at their time of breakup, together with the location of highly-stretched failed breakup basins and rifted micro-continents. For detailed analysis to constrain OCT structure, margin type (i.e. magma poor, "normal" or magma rich) and COB location, a suite of quantitative analytical methods may be used which include: (i) Crustal cross-sections showing Moho depth and crustal basement thickness from gravity inversion. (ii) Residual depth anomaly (RDA) analysis which is used to investigate OCT

  11. Transport and scavenging of biomass burning aerosols in the maritime continent

    NASA Astrophysics Data System (ADS)

    Lee, H. H.; Wang, C.

    2014-12-01

    Biomass burning frequently occurs in summertime over the maritime continent, especially in Malaysia peninsula, Sumatra, and Borneo. Under certain weather conditions, particulate matters emitted from such fires cause degrade of air quality and thus occurrence of often weekly long haze in downwind locations such as Singapore. It is possible that these biomass burning aerosols may have influenced convective clouds in the maritime continent though such cases have not been well simulated and understood. In order to improve understanding of the spatiotemporal coverage and influence of biomass burning aerosols in the maritime continent, we have used the Weather Research and Forecasting (WRF) model to study the transport of biomass burning aerosols from Malaysia peninsula, Sumatra, and Borneo, using biomass burning emissions from the Fire INventory from NCAR (FINN) version 1.0. We choose to use emissions from the month of August because the annual emissions peak often occurs within this month. Based on a multi-year ensemble simulation, we have examined the influences of various meteorological regimes on the aerosol transport and wet removal.

  12. Baculoviral mid-gut gland necrosis (BMN) of kuruma shrimp (Penaeus japonicus) larvae in Japanese intensive culture systems

    NASA Astrophysics Data System (ADS)

    Sano, T.; Nishimura, T.; Fukuda, H.; Hayashida, T.; Momoyama, K.

    1984-03-01

    In many shrimp farms in the Kyushu and Chugoku areas of Japan, the so-called mid-gut gland cloudy disease of kuruma shrimp larvae (Penaeus japonicus) has occurred since 1971. The pathological changes associated with this baculoviral mid-gut gland necrosis (BMN) are extensive cellular necrosis, collapse of mid-gut gland cells, nuclear hypertrophy and finally karyorrhexis. Electron microscopic examination revealed the presence of virions and virogenic stages in the affected nuclei. Average length and diameter of the virions detected was 310 and 72 nm, respectively; nucleocapsids were 250 nm in size. Virions enclosing 2 nucleocapsids within a single envelope were rarely found. The spirally arranged capsomeres were at an angle of 37 to 38° to a horizontal line meeting at right angles with the long axis of the virion. Infectivity trials resulted in high mortality of healthy mysis and juveniles (2nd post-larval stage). Juveniles at the 9th post-larval stage showed no mortality, although they could be infected easily by the agent. Hypertrophied nuclei in squashed and stained preparations of the affected gland cells can be considered to be of reliable presumptive diagnostic character, and fluorescent antibody staining can be employed to confirm the diagnosis of BMN.

  13. Neuromuscular Characterization of the Urethra in Continent Women

    PubMed Central

    Kenton, Kimberly; Mueller, Elizabeth; Brubaker, Linda

    2011-01-01

    Objectives To describe quantitative urethral function parameters in a racially diverse group of continent women. Materials and Methods Following Institutional Review Board approval, we recruited women without urinary incontinence from the community. To be considered continent, participants answered “never” to the first six questions on the stress subscale of the Medical, Epidemiologic, and Social Aspects of Aging urinary incontinence (MESA) questionnaire. Participants all underwent quantitative concentric urethral electromyography (EMG) and urodynamic testing (UDS). Results Thirty-one women with a mean±SD age of 39±14 years underwent EMG and UDS. The cohort was racially diverse with 13 Caucasians (43%), 13 African Americans (43%), and 4 Hispanics (14%). Body mass index (BMI) (P=.12, .06), age (P=.40, .64), and vaginal parity (P=.53, .76) did not differ by race or ethnicity. We did not detect differences in any EMG parameter by race, ethnicity or vaginally parity. A mean (range) of 30 motor unit action potential analysis (MUP) (10-55) were identified and analyzed in Multi-MUP analysis and 14 (8-21) were identified and analyzed in IP analysis. On average, 37±20% MUPs were polyphasic. Age significantly correlated with several measures of urethral sphincter function. Increasing age was inversely correlated with interference analysis (IP) turns (−.57, p=.001), IP amplitude (r=−.43, p=.02), IP turns/amplitude (r=−.54, p=.003), maximum urethral closure pressures (MUCP) (r=−.41, p=.04). Similarly, MUCP correlated with IP amplitude (r=.38, p=.04). Conclusions This urethral neuromuscular function data on the largest cohort of continent women fully characterized with quantitative urethral EMG demonstrates significant neuropathic MUP changes with advancing age. PMID:22453105

  14. 76 FR 82205 - Airworthiness Directives; Cessna Aircraft Company Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-30

    ... (ACO), 1801 Airport Road, Room 100, Mid- Continent Airport, Wichita, Kansas 67209; phone: (316) 946-4154; fax: (316) 946-4107; email: [email protected] . SUPPLEMENTARY INFORMATION: Comments Invited... (ACO), 1801 Airport Road, Room 100, Mid-Continent Airport, Wichita, Kansas 67209; phone: (316) 946-4154...

  15. Mid-frequency Band Dynamics of Large Space Structures

    NASA Technical Reports Server (NTRS)

    Coppolino, Robert N.; Adams, Douglas S.

    2004-01-01

    High and low intensity dynamic environments experienced by a spacecraft during launch and on-orbit operations, respectively, induce structural loads and motions, which are difficult to reliably predict. Structural dynamics in low- and mid-frequency bands are sensitive to component interface uncertainty and non-linearity as evidenced in laboratory testing and flight operations. Analytical tools for prediction of linear system response are not necessarily adequate for reliable prediction of mid-frequency band dynamics and analysis of measured laboratory and flight data. A new MATLAB toolbox, designed to address the key challenges of mid-frequency band dynamics, is introduced in this paper. Finite-element models of major subassemblies are defined following rational frequency-wavelength guidelines. For computational efficiency, these subassemblies are described as linear, component mode models. The complete structural system model is composed of component mode subassemblies and linear or non-linear joint descriptions. Computation and display of structural dynamic responses are accomplished employing well-established, stable numerical methods, modern signal processing procedures and descriptive graphical tools. Parametric sensitivity and Monte-Carlo based system identification tools are used to reconcile models with experimental data and investigate the effects of uncertainties. Models and dynamic responses are exported for employment in applications, such as detailed structural integrity and mechanical-optical-control performance analyses.

  16. A Subambient Open Roof Surface under the Mid-Summer Sun.

    PubMed

    Gentle, Angus R; Smith, Geoff B

    2015-09-01

    A novel material open to warm air stays below ambient temperature under maximum solar intensities of mid-summer. It is found to be 11 °C cooler than a commercial white cool roof nearby. A combination of specially chosen polymers and a silver thin film yields values near 100% for both solar reflectance, and thermal emittance at infrared wavelengths from 7.9 to 13 μm.

  17. Left-colon antegrade continence enema (LACE) procedure for fecal incontinence.

    PubMed

    Churchill, Bernard M; De Ugarte, Daniel A; Atkinson, James B

    2003-12-01

    Antegrade continence enemas (ACE) are an efficacious therapeutic option for patients with fecal incontinence. The authors review their institution's experience with a variation of the Monti-Malone ACE procedure using the left colon as a source of an intestinal conduit and enema reservoir. From 2000 to 2002, 18 patients with fecal incontinence or intractable constipation underwent left-colon ACE (LACE) procedure. Concomitant Mitrofanoff appendicovesicostomy was performed in 15 patients and bladder augmentation in 9. The majority of patients had neural tube defects. A segment of left colon was tubularized, tunneled into the muscular wall of the distal colon, and exteriorized through the left upper quadrant or midabdomen. Stomal catherization and enema installation were started one month postoperatively. Fifteen patients (83%) achieved fecal continence, 2 remain incontinent of stool, and 1 experienced stomal closure (mean follow-up was 24 +/- 9 months). Two patients had stomal stenosis that required revision. The mean enema volume in patient's achieving continence was 360 +/- 216 mL, and the mean transit time was 18 +/- 12 minutes. LACE is an efficacious procedure for fecal incontinence that can be performed safely at the time of major urologic reconstruction. Administration of enemas into the left colon has several physiologic advantages that result in predictable bowel evacuation.

  18. Generation and application of ultrashort coherent mid-infrared electromagnetic radiation

    NASA Astrophysics Data System (ADS)

    Wandel, Scott

    Particle accelerators are useful instruments that help address critical issues for the future development of nuclear energy. Current state-of-the-art accelerators based on conventional radio-frequency (rf) cavities are too large and expensive for widespread commercial use, and alternative designs must be considered for supplying relativistic beams to small-scale applications, including medical imaging, secu- rity screening, and scientific research in a university-scale laboratory. Laser-driven acceleration using micro-fabricated dielectric photonic structures is an attractive approach because such photonic microstructures can support accelerating fields that are 10 to 100 times higher than that of rf cavity-based accelerators. Dielectric laser accelerators (DLAs) use commercial lasers as a driving source, which are smaller and less expensive than the klystrons used to drive current rf-based accelerators. Despite the apparent need for compact and economical laser sources for laser-driven acceleration, the availability of suitable high-peak-power lasers that cover a broad spectral range is currently limited. To address the needs of several innovative acceleration mechanisms like DLA, it is proposed to develop a coherent source of mid-infrared (IR) electromagnetic radiation that can be implemented as a driving source of laser accelerators. The use of ultrashort mid-IR high peak power laser systems in various laser-driven acceleration schemes has shown the potential to greatly reduce the optical pump intensities needed to realize high acceleration gradients. The optical intensity needed to achieve a given ponderomotive potential is 25 times less when using a 5-mum mid-IR laser as compared to using a 1-mum near-IR solid-state laser. In addition, dielectric structure breakdown caused by multiphoton ionization can be avoided by using longer-wavelength driving lasers. Current mid-IR laser sources do not produce sufficiently short pulse durations, broad spectral bandwidths

  19. Indicators of climate change for the African continent derived from radiosondes

    NASA Astrophysics Data System (ADS)

    Añel, J. A.; Gimeno, L.; Tesouro, M.; de La Torre, L.; Nieto, R.; Ribera, P.; García, R.; Hernández, E.

    2003-04-01

    Here we study the interannual variability of different parameters calculated from radiosonde data in the African continent. Data used in the analysis were a subset of the National Climatic Data Center Upper Air Digital Files of the National Oceanic and Atmospheric Administration (USA) (CARDS). This work show the climatic trends in the studied region during the period and from 1973 to 1998). Results show that radiosonde stations were useful for this analysis in the African continent. Main oscillations and the relationship with the Northern Annular Mode and El Niño-Southern Oscillation were also studied.

  20. Novel dental adhesive containing antibacterial agents and calcium phosphate nanoparticles

    PubMed Central

    Melo, Mary Anne S.; Cheng, Lei; Weir, Michael D.; Hsia, Ru-ching; Rodrigues, Lidiany K. A.; Xu, Hockin H. K.

    2013-01-01

    Secondary caries remains the main reason for dental restoration failure. Replacement of failed restorations accounts for 50-70% of all restorations performed. Antibacterial adhesives could inhibit biofilm acids at tooth-restoration margins, and calcium phosphate (CaP) ions could remineralize tooth lesions. The objectives of this study were to: (1) incorporate nanoparticles of silver (NAg), quaternary ammonium dimethacrylate (QADM), and nanoparticles of amorphous calcium phosphate (NACP) into bonding agent; and (2) investigate their effects on dentin bonding and microcosm biofilms. An experimental primer was made with pyromellitic glycerol dimethacrylate (PMGDM) and 2-hydroxyethyl methacrylate (HEMA). An adhesive was made with bisphenol-A-glycerolate dimethacrylate (BisGMA) and triethylene glycol dimethacrylate (TEGDMA). NAg was incorporated into primer at 0.1wt%. The adhesive contained 0.1% NAg and 10% QADM, and 0-40% NACP. Incorporating NAg into primer and NAg-QADM-NACP into adhesive did not adversely affect dentin bond strength (p>0.1). SEM showed numerous resin tags, and TEM revealed NAg and NACP in dentinal tubules. Viability of human saliva microcosm biofilms on primer/adhesive/composite disks was substantially reduced via NAg and QADM. Metabolic activity, lactic acid, and colony-forming units of biofilms were much lower on the new bonding agents than control (p<0.05). In conclusion, novel dental bonding agents containing NAg, QADM and NACP were developed with the potential to kill residual bacteria in the tooth cavity and inhibit the invading bacteria along tooth-restoration margins, with NACP to remineralize tooth lesions. The novel method of combining antibacterial agents (NAg and QADM) with remineralizing agent (NACP) may have wide applicability to other adhesives for caries inhibition. PMID:23281264

  1. Does menopausal status impact urinary continence outcomes following abdominal sacrocolpopexy without anti-incontinence procedures in continent women?

    PubMed Central

    Inan, Abdurrahman Hamdi; Toz, Emrah; Beyan, Emrah; Gurbuz, Tutku; Ozcan, Aykut; Oner, Oznur

    2016-01-01

    Objective: We investigated the impact of menopausal status on urinary continence following abdominal sacrocolpopexy (ASC) without an anti-incontinence procedure in continent women. Methods: We conducted a clinical follow-up study of 137 patients diagnosed with stage 3 or higher pelvic organ prolapse (POP) without urinary incontinence between January 2012 and December 2014. Patients were provided with detailed a priori information pertaining to the abdominal sacrocolpopexy procedure and were invited to attend follow-up visits at 1, 3, 12, and 24 months. Follow-up visits included a gynecological examination, cough test, and validated Urinary Distress Inventory-6 (UDI-6) and Incontinence Impact Questionnaire-7 (IIQ-7) questionnaires. Results: The mean follow-up time for the cohort was 16.5±3.45 months. The study group was divided according to menopausal status: premenopausal (Group-1) and postmenopausal women (Group-II). Anatomical recurrence was not detected during the follow-up period in either group, but de novo stress urinary incontinence was seen in 15 of 53 (28.3%) Group-I patients and in 6 of 84 (7.1%; p < 0.01) Group-II patients. Conclusions: The risk of de novo stress urinary incontinence in postmenopausal women after ASC is low. However, premenopausal patients have a higher incidence of de novo stress incontinence which affect quality of life. PMID:27648027

  2. Is continence status associated with quality of life in young children with spina bifida?

    PubMed

    Freeman, Kurt A; Smith, Kathryn; Adams, Elizabeth; Mizokawa, Stacey; Neville-Jan, Ann

    2013-01-01

    To evaluate the relationship between child- and parent-reported quality of life (QOL) and bowel and bladder continence among young children with spina bifida (SB). 104 children ages 5-12 years and one of their parents/guardians completed the Pediatric Quality of Life Inventory - Generic Form (PedsQL; parent and child) and the Quality of Life in Spina Bifida Questionnaire (QOLSBQ, parent only). Data on continence, child age, and condition-specific variables were obtained by chart review. Parent and child QOL scores (on all measures of QOL) were positively correlated; parents rated child QOL lower than children's self report. QOL scores did not differ based on continence status. Total PedsQL scores were associated with age and mobility based on child report and with mobility based on parent report. QOL may not be affected by continence status among young children with SB, though demographic (i.e., age) and condition-specific (i.e., functional mobility status) variables appear relevant. Additional research is needed to further evaluate condition-specific variables, other protective variables, and possible measurement issues that influence QOL in young children with SB.

  3. Mid-latitude SuperDARN Measurements of the Extended Local Time Structure and Dynamics of Sub-Auroral Plasma Streams

    NASA Astrophysics Data System (ADS)

    Greenwald, R. A.; Ruohoniemi, J. M.; Shepherd, S. G.; Talaat, E. R.; Bristow, W. A.; Baker, J. B.

    2011-12-01

    Over the past several years, funding from the National Science Foundation Mid-Sized Infrastructure (MSI) Program has enabled the expansion of a mid-latitude network of SuperDARN HF radars. Currently the network spans the continental U.S.A and includes previously developed radars at Wallops Island and Blackstone, VA and four MSI-funded radars. Two of the MSI radars are located near Hays, Kansas and two are located near Christmas Valley, Oregon. With the current configuration of radars, it has been possible to detect sub-auroral plasma streams (SAPS), identified as latitudinally-narrow high-velocity flow regions equatorward of the main auroral electron precipitation zone, that extend over the breadth of the North American continent and the neighboring regions of the Atlantic and Pacific Oceans. SAPS have previously been reported using data from low-altitude polar-orbiting spacecraft, incoherent scatter radars, and the SuperDARN radars, but these are amongst the first observations of the SAPS velocity structure as it is observed over 6 or more hours of local time and for durations ranging up to 8 hours of real time. The SAPS flow channel is most clearly observed when there is good coupling between the solar wind and the Earth's magnetosphere (Southward IMF). As the IMF varies between southward and northward, the intensity of the flow is modulated, but the geomagnetic location of the SAPS channel does not change dramatically. To date, SAPS channels exhibiting the characteristics described above are most commonly observed under moderately disturbed conditions (Kp=3,4) and are commonly located near 60 degrees geomagnetic. The latitude of the SAPS feature decreases by several degrees between the dusk and midnight sectors. Overall, the SAPs feature appears to be an important localized flow enhancement that maps to a significant local time sector of the inner magnetosphere and it is surprisingly responsive to changes in solar-wind magnetosphere coupling. The extended

  4. Generating structured light with phase helix and intensity helix using reflection-enhanced plasmonic metasurface at 2 μm

    NASA Astrophysics Data System (ADS)

    Zhao, Yifan; Du, Jing; Zhang, Jinrun; Shen, Li; Wang, Jian

    2018-04-01

    Mid-infrared (2-20 μm) light has been attracting great attention in many areas of science and technology. Beyond the extended wavelength range from visible and near-infrared to mid-infrared, shaping spatial structures may add opportunities to grooming applications of mid-infrared photonics. Here, we design and fabricate a reflection-enhanced plasmonic metasurface and demonstrate efficient generation of structured light with the phase helix and intensity helix at 2 μm. This work includes two distinct aspects. First, structured light (phase helix, intensity helix) generation at 2 μm, which is far beyond the ability of conventional spatial light modulators, is enabled by the metasurface with sub-wavelength engineered structures. Second, the self-referenced intensity helix against environmental noise is generated without using a spatially separated light. The demonstrations may open up advanced perspectives to structured light applications at 2 μm, such as phase helix for communications and non-communications (imaging, sensing) and intensity helix for enhanced microscopy and advanced metrology.

  5. Challenges and Psychosocial Growth for Older Volunteers Giving Intensive Humanitarian Service

    ERIC Educational Resources Information Center

    Piercy, Kathleen W.; Cheek, Cheryl; Teemant, Boyd

    2011-01-01

    Purpose of the study: We conducted a qualitative study of 38 mid-late life volunteers in intensive humanitarian service to ascertain the challenges, personal changes, and benefits they experienced from their volunteer activities. Intensive volunteering was defined as service done on a 24-hr a day basis at a location away from home. Design and…

  6. Mantle flow and deforming continents, the Tethys realm

    NASA Astrophysics Data System (ADS)

    Jolivet, L.; Faccenna, C.; Becker, T. W.

    2016-12-01

    Continent deformation is partly a consequence of plate motion along plate boundaries. Whether underlying asthenospheric flow can also deform continents through basal shear or push on topographic irregularities of the base of the lithosphere is an open question. Eurasia has been extending at different scales since 50 Ma, from the Mediterranean back-arc domains to extension of Asia between the India-Asia collision zone and the Pacific subduction zones. While compression at plate margins, in subduction or collision zones can propagate far within continents, the mechanism explaining extension distributed over thousands of kilometres is unclear. We use trajectories of continental plates and continental fragments since 50 Myrs in different kinematic frames and compare them with various proxies of asthenospheric flow such as seismic anisotropy at various depths. These trajectories partly fit sub-lithospheric seismic anisotropy with two main circulations, one carrying Africa and Eurasia away from the large low velocity anomaly (LLSVP) underlying South and West Africa and one carrying the Pacific plate away from the LLSVP underlying the southern Pacific. Under eastern Eurasia the flow converges with the Pacific flow and distributed extension affects eastern Asia all the way to Western Pacific back-arc basins. We speculate that the flow carrying India northward and Eurasia eastward has invaded the Pacific domain and caused this widely distributed extension that interferes with the strike-slip faults issued from the Himalaya-Tibet collision zone. This model is in line with earlier propositions based on geochemical proxies. We discuss this model and compare it to other widely distributed extensional deformation episodes such as the Early Cretaceous extension of Africa and finally propose a scheme of large-scale continental deformation in relation to underlying mantle convection at different scales.

  7. OxyContin Use on a Rural Midwest American Indian Reservation: Demographic Correlates and Reasons for Using

    PubMed Central

    Momper, Sandra L.; Delva, Jorge; Tauiliili, Debbie; Mueller-Williams, Amelia Cromwell; Goral, Patricia

    2013-01-01

    In 2009 we surveyed 400 tribal members of a midwestern American Indian reservation to assess the prevalence of OxyContin use. Thirty percent of tribal participants reported nonmedical use of OxyContin ever, 18.9% in the past year, and 13.4% in the past month. Participants aged 18 to 25 years were most likely to have used OxyContin. Reasons given for use of the drug included pain relief (59.3%) and getting high (52.2%), indicating a need for opioid treatment programs. PMID:24028230

  8. 77 FR 24349 - Airworthiness Directives; Learjet Inc. Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-04-24

    ..., Kansas 67209-2942; telephone 316-946-2000; fax 316-946-2220; email [email protected] ; Internet... 100, Mid- Continent Airport, Wichita, Kansas 67209; phone: 316-946-4135; fax: 316-946-4107; email... Road, Room 100, Mid-Continent Airport, Wichita, Kansas 67209; phone: 316- 946-4135; fax: 316-946-4107...

  9. Regional climate modeling over the Maritime Continent: Assessment of RegCM3-BATS1e and RegCM3-IBIS

    NASA Astrophysics Data System (ADS)

    Gianotti, R. L.; Zhang, D.; Eltahir, E. A.

    2010-12-01

    Despite its importance to global rainfall and circulation processes, the Maritime Continent remains a region that is poorly simulated by climate models. Relatively few studies have been undertaken using a model with fine enough resolution to capture the small-scale spatial heterogeneity of this region and associated land-atmosphere interactions. These studies have shown that even regional climate models (RCMs) struggle to reproduce the climate of this region, particularly the diurnal cycle of rainfall. This study builds on previous work by undertaking a more thorough evaluation of RCM performance in simulating the timing and intensity of rainfall over the Maritime Continent, with identification of major sources of error. An assessment was conducted of the Regional Climate Model Version 3 (RegCM3) used in a coupled system with two land surface schemes: Biosphere Atmosphere Transfer System Version 1e (BATS1e) and Integrated Biosphere Simulator (IBIS). The model’s performance in simulating precipitation was evaluated against the 3-hourly TRMM 3B42 product, with some validation provided of this TRMM product against ground station meteorological data. It is found that the model suffers from three major errors in the rainfall histogram: underestimation of the frequency of dry periods, overestimation of the frequency of low intensity rainfall, and underestimation of the frequency of high intensity rainfall. Additionally, the model shows error in the timing of the diurnal rainfall peak, particularly over land surfaces. These four errors were largely insensitive to the choice of boundary conditions, convective parameterization scheme or land surface scheme. The presence of a wet or dry bias in the simulated volumes of rainfall was, however, dependent on the choice of convection scheme and boundary conditions. This study also showed that the coupled model system has significant error in overestimation of latent heat flux and evapotranspiration from the land surface, and

  10. Dynamic rectus abdominis muscle sphincter for stoma continence: an acute functional study in a dog model.

    PubMed

    Bardoel, J W; Stadelmann, W K; Perez-Abadia, G A; Galandiuk, S; Zonnevijlle, E D; Maldonado, C; Stremel, R W; Tobin, G R; Kon, M; Barker, J H

    2001-02-01

    Fecal stomal incontinence is a problem that continues to defy surgical treatment. Previous attempts to create continent stomas using dynamic myoplasty have had limited success due to denervation atrophy of the muscle flap used in the creation of the sphincter and because of muscle fatigue resulting from continuous electrical stimulation. To address the problem of denervation atrophy, a stomal sphincter was designed using the most caudal segment of the rectus abdominis muscle, preserving its intercostal innervation as well as its vascular supply. The purpose of the present study was to determine whether this rectus abdominis muscle island flap sphincter design could maintain stomal continence acutely. In this experiment, six dogs were used to create eight rectus abdominis island flap stoma sphincters around a segment of distal ileum. Initially, the intraluminal stomal pressures generated by the sphincter using different stimulation frequencies were determined. The ability of this stomal sphincter to generate continence at different intraluminal bowel pressures was then assessed. In all cases, the rectus abdominis muscle sphincter generated peak pressures well above those needed to maintain stomal continence (60 mmHg). In addition, each sphincter was able to maintain stomal continence at all intraluminal bowel pressures tested.

  11. New Caledonia a classic example of an arc continent collision

    NASA Astrophysics Data System (ADS)

    Aitchison, J.

    2011-12-01

    The SW Pacific island of New Caledonia presents a classic example of an arc-continent collision. This event occurred in the Late Eocene when elements of an intra-oceanic island arc system, the Loyalty-D'Entrecasteaux arc, which stretched SSE from near Papua New Guinea east of New Caledonia to offshore New Zealand, collided with micro-continental fragments that had rifted off eastern Gondwana (Australia) in the late Cretaceous. Intervening Late Cretaceous to Paleogene oceanic crust of the South Loyalty Basin was eliminated through eastward subduction beneath this west-facing intra-oceanic island arc. As with many arc-continent collisions elsewhere collision was accompanied by ophiolite emplacement. The erosional remnants of which are extensive in New Caledonia. Collision led to subduction flip, followed by extensive rollback in front of the newly established east-facing Vitiaz arc. Post-collisional magmatism occurred after slab break-off and is represented by small-scale granitoid intrusions. Additional important features of New Caledonia include the presence of a regionally extensive UHP metamorphic terrain consisting of blueschists and eclogites that formed during the subduction process and were rapidly exhumed as a result of the collision Not only was collision and associated orogeny short-lived this collision system has not been overprinted by any major subsequent collision. New Caledonia thus provides an exceptional location for the study of processes related to arc-continent collision in general.

  12. African Cenozoic hotpot tectonism: new insights from continent-scale body-wave tomography

    NASA Astrophysics Data System (ADS)

    Bastow, I. D.; Boyce, A.; Caunt, E.; Guilloud De Courbeville, J.; Desai, S.; Kounoudis, R.; Golos, E. M.; Burdick, S.; van der Hilst, R. D.

    2017-12-01

    The African plate is an ideal study locale for mantle plumes and Cenozoic hotspot tectonism. On the eastern side of the continent, the uplifted East African and Ethiopian plateaus, and the 30Ma Ethiopian Traps, are widely considered to be the result of the African Superplume: a broad thermochemical anomaly that originates below southern Africa. Precisely where and how the superplume traverses the mantle transition zone is debated however. On the western side of the continent, the Cameroon Volcanic Line is a hotspot track with no age-progression; it is less easily attributed to the effects of a mantle plume. Central to our understanding of these issues is an improved picture of mantle seismic structure. Body-wave studies of African mantle wave-speed structure are typically limited to regional relative arrival-time studies that utilize data from temporary seismograph networks of aperture less than 1000km. The resulting tomographic images are higher resolution than continent-scale surface-wave models, but anomaly amplitudes cannot be compared from region to region using the relative arrival-time approach: the 0% contour in each region refers to the regional, not global mean. The challenge is thus to incorporate the often-noisy body-wave data from temporary seismograph networks into a continent-scale absolute delay-time model. We achieve this using the new Absolute Arrival-time Recovery Method (AARM) method of Boyce et. al., (2017) and the tomographic inversion approach described by Li et. al., (2008). We invert for mantle wavespeed structure using data recorded since 1990 by temporary networks in the Atlas Mountains, Cameroon, South Africa, East African Rift system, Ethiopia and Madagascar. Our model is well resolved to lower mantle depths beneath these temporary networks, and offers the most detailed picture yet of mantle wavespeed structure beneath Africa. The contrast between East African and Cameroon mantle structure suggests multiple development mechanisms for

  13. Fluid inclusion gas chemistry as a potential minerals exploration tool: Case studies from Creede, CO, Jerritt Canyon, NV, Coeur d'Alene district, ID and MT, southern Alaska mesothermal veins, and mid-continent MVT's

    USGS Publications Warehouse

    Landis, G.P.; Hofstra, A.H.

    1991-01-01

    Recent advances in instrumentation now permit quantitative analysis of gas species from individual fluid inclusions. Fluid inclusion gas data can be applied to minerals exploration empirically to establish chemical (gas composition) signatures of the ore fluids, and conceptually through the development of genetic models of ore formation from a framework of integrated geologic, geochemical, and isotopic investigations. Case studies of fluid inclusion gas chemistry from ore deposits representing a spectrum of ore-forming processes and environments are presented to illustrate both the empirical and conceptual approaches. We consider epithermal silver-gold deposits of Creede, Colorado, Carlin-type sediment-hosted disseminated gold deposits of Jerritt Canyon, Nevada, metamorphic silver-base-metal veins of the Coeur d'Alene district, Idaho and Montana, gold-quartz veins in accreted terranes of southern Alaska, and the mid-continent base-metal sulfide deposits of Mississippi Valley-Type (MVT's). Variations in gas chemistry determine the redox state of the ore fluids, provide compositional input for gas geothermometers, characterize ore fluid chemistry (e.g., CH4CO2, H2SSO2, CO2/H2S, organic-rich fluids, gas-rich and gas-poor fluids), identify magmatic, meteoric, metamorphic, shallow and deep basin fluids in ore systems, locate upwelling plumes of magmatic-derived volatiles, zones of boiling and volatile separation, interfaces between contrasting fluids, and important zones of fluid mixing. Present techniques are immediately applicable to exploration programsas empirical studies that monitor fluid inclusion gas threshold concentration levels, presence or absence of certain gases, or changes in gas ratios. We suggest that the greater contribution of fluid inclusion gas analysis is in the integrated and comprehensive chemical dimension that gas data impart to genetic models, and in the exploration concepts based on processes and environments of ore formation derived from

  14. Continence and quality-of-life outcomes 6 months following an intensive pelvic-floor muscle exercise program for female stress urinary incontinence: a randomized trial comparing low- and high-frequency maintenance exercise.

    PubMed

    Borello-France, Diane F; Downey, Patricia A; Zyczynski, Halina M; Rause, Christine R

    2008-12-01

    Few studies have examined the effectiveness of pelvic-floor muscle (PFM) exercises to reduce female stress urinary incontinence (SUI) over the long term. This study: (1) evaluated continence and quality-of-life outcomes of women 6 months following formalized therapy and (2) determined whether low- and high-frequency maintenance exercise programs were equivalent in sustaining outcomes. Thirty-six women with SUI who completed an intensive PFM exercise intervention trial were randomly assigned to perform a maintenance exercise program either 1 or 4 times per week. Urine leaks per week, volume of urine loss, quality of life (Incontinence Impact Questionnaire [IIQ] score), PFM strength (Brink score), and prevalence of urodynamic stress incontinence (USI) were measured at a 6-month follow-up for comparison with postintervention status. Parametric and nonparametric statistics were used to determine differences in outcome status over time and between exercise frequency groups. Twenty-eight women provided follow-up data. Postintervention status was sustained at 6 months for all outcomes (mean [SD] urine leaks per week=1.2+/-2.1 versus 1.4+/-3.1; mean [SD] urine loss=0.2+/-0.5 g versus 0.2+/-0.8 g; mean [SD] IIQ score=17+/-20 versus 22+/-30; mean [SD] Brink score=11+/-1 versus 11+/-1; and prevalence of USI=48% versus 35%). Women assigned to perform exercises once or 4 times per week similarly sustained their postintervention status. Benefits of an initial intensive intervention program for SUI were sustained over 6 months. However, only 15 of the 28 women provided documentation of their exercise adherence, limiting conclusions regarding the need for continued PFM exercise during follow-up intervals of

  15. Novel dental adhesives containing nanoparticles of silver and amorphous calcium phosphate

    PubMed Central

    Melo, Mary Anne S.; Cheng, Lei; Zhang, Ke; Weir, Michael D.; Rodrigues, Lidiany K. A.; Xu, Hockin H. K.

    2012-01-01

    Objectives Secondary caries is the main reason for restoration failure, and replacement of the failed restorations accounts for 50–70% of all restorations. Antibacterial adhesives could inhibit residual bacteria in tooth cavity and invading bacteria along the margins. Calcium (Ca) and phosphate (P) ion release could remineralize the lesions. The objectives of this study were to incorporate nanoparticles of silver (NAg) and nanoparticles of amorphous calcium phosphate (NACP) into adhesive for the first time, and to investigate the effects on dentin bond strength and plaque microcosm biofilms. Methods Scotchbond Multi-Purpose adhesive was used as control. NAg were added into primer and adhesive at 0.1% by mass. NACP were mixed into adhesive at 10%, 20%, 30% and 40%. Microcosm biofilms were grown on disks with primer covering the adhesive on a composite. Biofilm metabolic activity, colony-forming units (CFU) and lactic acid were measured. Results Human dentin shear bond strengths (n=10) ranged from 26 to 34 MPa; adding NAg and NACP into adhesive did not decrease the bond strength (p > 0.1). SEM examination revealed resin tags from well-filled dentinal tubules. Numerous NACP infiltrated into the dentinal tubules. While NACP had little antibacterial effect, NAg in bonding agents greatly reduced the biofilm viability and metabolic activity, compared to the control (p < 0.05). CFU for total microorganisms, total streptococci, and mutans streptococci on bonding agents with NAg were an order of magnitude less than those of the control. Lactic acid production by biofilms for groups containing NAg was 1/4 of that of the control. Significance Dental plaque microcosm biofilm viability and acid production were greatly reduced on bonding agents containing NAg and NACP, without compromising dentin bond strength. The novel method of incorporating dual agents (remineralizing agent NACP and antibacterial agent NAg) may have wide applicability to other dental bonding systems. PMID

  16. Development of a multifunctional adhesive system for prevention of root caries and secondary caries

    PubMed Central

    Zhang, Ning; Melo, Mary A. S.; Chen, Chen; Liu, Jason; Weir, Michael D.; Bai, Yuxing; Xu, Hockin H. K.

    2015-01-01

    Objectives The objectives of this study were to: (1) develop a novel adhesive for prevention of tooth root caries and secondary caries by possessing a combination of protein-repellent, antibacterial, and remineralization capabilities for the first time; and (2) investigate the effects of 2-methacryloyloxyethyl phosphorylcholine (MPC), dimethylaminohexadecyl methacrylate (DMAHDM), and nanoparticles of amorphous calcium phosphate (NACP) on dentine bond strength, protein-repellent properties, and dental plaque microcosm biofilm response. Methods MPC, DMAHDM and NACP were added into Scotchbond Multi-Purpose primer and adhesive. Dentine shear bond strengths were measured. Adhesive coating thickness, surface texture and dentine-adhesive interfacial structure were examined. Protein adsorption onto adhesive resin surface was determined by the micro bicinchoninic acid method. A human saliva microcosm biofilm model was used to investigate biofilm metabolic activity, colony-forming unit (CFU) counts, and lactic acid production. Results The resin with 7.5% MPC + 5% DMAHDM + 30% NACP did not adversely affect dentine shear bond strength (p > 0.1). The resin with 7.5% MPC + 5% DMAHDM + 30% NACP produced a coating on root dentine with a thickness of approximately 70 μm and completely sealed all the dentinal tubules. The resin with 7.5% MPC + 5% DMAHDM + 30% NACP had 95% reduction in protein adsorption, compared to SBMP control (p < 0.05). The resin with 7.5% MPC + 5% DMAHDM + 30% NACP was strongly antibacterial, with biofilm CFU being four orders of magnitude lower than that of SBMP control. Significance The novel multifunctional adhesive with strong protein-repellent, antibacterial and remineralization properties is promising to coat tooth roots to prevent root caries and secondary caries. The combined use of MPC, DMAHDM and NACP may have wide applicability to bonding agents, cements, sealants and composites to inhibit caries. PMID:26187532

  17. 21 CFR 876.5310 - Nonimplanted, peripheral electrical continence device.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Nonimplanted, peripheral electrical continence device. 876.5310 Section 876.5310 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Therapeutic Devices § 876...

  18. 21 CFR 876.5310 - Nonimplanted, peripheral electrical continence device.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 8 2014-04-01 2014-04-01 false Nonimplanted, peripheral electrical continence device. 876.5310 Section 876.5310 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GASTROENTEROLOGY-UROLOGY DEVICES Therapeutic Devices § 876...

  19. 76 FR 78520 - Airworthiness Directives; Learjet Inc. Airplanes

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-19

    ... Learjet, Inc., One Learjet Way, Wichita, Kansas 67209-2942; telephone (316) 946-2000; fax (316) 946-2220... Road, Room 100, Mid-Continent Airport, Wichita, KS 67209; phone: (316) 946-4152; fax: (316) 946-4129... 100, Mid-Continent Airport, Wichita, KS 67209; phone: (316) 946-4152; fax: (316) 946-4129; email: paul...

  20. 75 FR 44881 - Special Conditions: Garmin International G1000 and GFC700 System Installation in the Cessna Model...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-30

    ... the Cessna Model 525 Citation Jet; Installation of Mid- Continent MD835 Lithium Ion Battery AGENCY... MD835 Lithium Ion (Li-ion) battery. The applicable airworthiness regulations do not contain adequate or... installation of the Mid-Continent Instruments MD835 Lithium Ion battery in the G1000 & GFC700 equipped Cessna...

  1. The OxyContin crisis: problematisation and responsibilisation strategies in addiction, pain, and general medicine journals.

    PubMed

    Whelan, Emma; Asbridge, Mark

    2013-09-01

    OxyContin(®) (Purdue Pharma, L.P., Stamford, CT) is now widely regarded as a drug of abuse fueling a larger opioid health crisis. While coverage in the North American press about OxyContin overwhelmingly focused upon the problems of related crime and addiction/misuse and the perspectives of law enforcement officials and police, coverage in those fields of medicine most intimately concerned with OxyContin-pain medicine and addiction medicine-was more nuanced. In this article, we draw upon the constructivist social problems tradition and Hunt's theory of moral regulation in a qualitative analysis of 24 medical journal articles. We compare and contrast pain medicine and addiction medicine representations of the OxyContin problem, the agents responsible for it, and proposed solutions. While there are some significant differences, particularly concerning the nature of the problem and the agents responsible for it, both pain medicine and addiction medicine authors 'take responsibility' in ways that attempt to mitigate the potential appropriation of the issue by law enforcement and regulatory agencies. The responses of pain medicine and addiction medicine journal articles represent strategic moves to recapture lost credibility, to retain client populations and tools necessary to their jobs, and to claim a seat at the table in responding to the OxyContin crisis. Copyright © 2013 Elsevier B.V. All rights reserved.

  2. Early return of continence in patients undergoing robot-assisted laparoscopic prostatectomy using modified maximal urethral length preservation technique.

    PubMed

    Hamada, Alaa; Razdan, Shirin; Etafy, Mohamed H; Fagin, Randy; Razdan, Sanjay

    2014-08-01

    To evaluate the impact of maximal urethral length preservation (MULP) technique in comparison with posterior urethral reconstruction and anterior bladder suspension (PRAS) technique on the continence rates (CR), time to achieve continence among patients with prostate cancer (PCa) undergoing robot-assisted laparoscopic prostatectomy (RALP). We prospectively analyzed the CR, time to achieve continence, pre- and postoperative prostate-specific antigen (PSA) levels, rates of positive margins among three groups of continent men with PCa undergoing RALP from whom consent was obtained. Each group consisted of 30 patients: PRAS was performed in group A, combined MULP and PRAS in group B, and MULP in group C. Continence was measured by patient self-reporting of the number of pads/24 h. No differences were detected in the age, preoperative PSA levels, biochemical recurrence, prostate volume, and positive margins for the three groups. Men in groups B and C had marked improvement in CR 1, 3, and 6 months after catheter removal vs group A (50% and 70% vs 10%, 90% and 96.66% vs 23.3% and 100%, 100% vs 53.3%, respectively, P<0.0001). The average and median times to continence were significantly shorter in group B (5.4 and 4 weeks) and C (3.8 and 3 weeks) vs group A (27.4 and 22.5 weeks), P<0.00001. Using Cox regression analysis, only MULP and MULP+PRAS techniques were significantly correlated with continence outcomes 1, 3, and 6 months after catheter removal. MULP rather than PRAS confers higher postoperative CR and shorter time to achieve continence among patients with PCa who underwent RALP without increasing risk of positive margin.

  3. Finite-Frequency Seismic Imaging of Upper-Mantle Velocity Structures Beneath the South China Continent

    NASA Astrophysics Data System (ADS)

    Qu, P.; Chen, Y. J.; Yu, Y.

    2017-12-01

    South China Continent is major formed from the Paleo-South China plate. The continent has experienced complicated tectonic history after Neoproterozoic. Previous studies suggested some possible model for the collision between South China Continent and North China Continent. Body wave tomography and surface wave tomography are widely used to inverse upper mantle velocity structure. In our study, finite frequency tomography were carried on to get explanation more correctly. We gathered nearly 60000 pieces of teleseismic event records by 166 broad band seismic stations with Mw > 5.5. Here sensitive kernel of ak135 velocity structure was calculated, which is based on Born approximation, and then we applied multi-channel cross-correlation to pick arrival time difference under 3 frequency band. Combining with crust thickness correct from receiver function, we solve the inversion matrix by LSQR method, and get accurate upper mantle structure of P, S velocity. For more accurate results, we apply a method to calculate Vp/Vs ratio, to help to verify the velocity anomaly. The result in this research shows: 1. A strong velocity anomaly exists in the northern of South China Continent, in an area 31°N between 112°-118°E. The anomaly is about . We suggest that, this anomaly is related to the collision from North China Continent. It implies the collision underthrusted to southward. 2. A clearly slow velocity anomaly exists in the northern of Cathaysia block. This low velocity anomaly exist on the boundary of Yangtz block and Cathysian block, it is related to the left over of block collision in early phanerozoic. 3. We recognized some little velocity anomaly exit in the research area. Comparing these velocity anomaly with U-Pb zircon ages, we suggest complicated orogenesis in Phanerozoic is the cause of the formation of these little anomaly. The result in our study support the collision model, which shows the underthrust direction is southward, on the south of Qinling

  4. Mechanism of continence after repair of posterior urethral disruption: evidence of rhabdosphincter activity.

    PubMed

    Whitson, Jared M; McAninch, Jack W; Tanagho, Emil A; Metro, Michael J; Rahman, Nadeem U

    2008-03-01

    Controversy exists regarding continence mechanisms in patients who undergo posterior urethral reconstruction after pelvic fracture. Some evidence suggests that continence after posterior urethroplasty is maintained by the bladder neck or proximal urethral mechanism without a functioning distal mechanism. We studied distal urethral sphincter activity in patients who have undergone posterior urethroplasty for pelvic fracture. A total of 12 patients who had undergone surgical repair of urethral disruption involving the prostatomembranous region underwent videourodynamics with urethral pressure profiles at rest, and during stress and hold maneuvers. Bladder pressure and urethral pressure, including proximal and distal urethral sphincter activity and pressure, were assessed in each patient. All 12 patients had daytime continence of urine postoperatively with a followup after anastomotic urethroplasty of 12 to 242 months (mean 76). Average maximum urethral pressure was 71 cm H2O. Average maximum urethral closure pressure was 61 cm H2O. The average urethral pressure seen during a brief hold maneuver was 111 cm H2O. Average functional sphincteric length was 2.5 cm. Six of the 12 patients had clear evidence of distal urethral sphincter function, as demonstrated by the profile. Continence after anastomotic urethroplasty for posttraumatic urethral strictures is maintained primarily by the proximal bladder neck. However, there is a significant contribution of the rhabdosphincter in many patients.

  5. Sediment toxicity in mid-continent great rivers (USA)

    EPA Science Inventory

    In this study, 530 sediment samples were collected from 447 sites between 2004 and 2006 at randomly selected shoreline sites along the main channel of the Ohio, Missouri and Upper Mississippi Rivers as part of the Environmental Monitoring and Assessment Program for Great Rivers E...

  6. Cold cratonic roots and thermal blankets: How continents affect mantle convection

    USGS Publications Warehouse

    Trubitsyn, V.P.; Mooney, W.D.; Abbott, D.H.

    2003-01-01

    Two-dimensional convection models with moving continents show that continents profoundly affect the pattern of mantle convection. If the continents are wider than the wavelength of the convection cells (???3000 km, the thickness of the mantle), they cause neighboring deep mantle thermal upwellings to coalesce into a single focused upwelling. This focused upwelling zone will have a potential temperature anomaly of about 200??C, much higher than the 100??C temperature anomaly of upwelling zones generated beneath typical oceanic lithosphere. Extensive high-temperature melts (including flood basalts and late potassic granites) will be produced, and the excess temperature anomaly will induce continental uplift (as revealed in sea level changes) and the eventual breakup of the supercontinent. The mantle thermal anomaly will persist for several hundred million years after such a breakup. In contrast, small continental blocks (<1000 km diameter) do not induce focused mantle upwelling zones. Instead, small continental blocks are dragged to mantle downwelling zones, where they spend most of their time, and will migrate laterally with the downwelling. As a result of sitting over relatively cold mantle (downwellings), small continental blocks are favored to keep their cratonic roots. This may explain the long-term survival of small cratonic blocks (e.g., the Yilgarn and Pilbara cratons of western Australia, and the West African craton). The optimum size for long-term stability of a continental block is <3000 km. These results show that continents profoundly affect the pattern of mantle convection. These effects are illustrated in terms of the timing and history of supercontinent breakup, the production of high-temperature melts, and sea level changes. Such two-dimensional calculations can be further refined and tested by three-dimensional numerical simulations of mantle convection with moving continental and oceanic plates.

  7. The ribbon continent of northwestern South America

    NASA Astrophysics Data System (ADS)

    Altamira-Areyan, Armando

    The tectonic structure of the Plate Boundary Zone (PBZ) between the Caribbean Plate (CARIB) and the South American Plate (SOAM) is interpreted using models that require CARIB motion from the Pacific into the Atlantic. Those models can be subdivided into: (1) those in which the island arc rocks that are now in the CARIB-SOAM PBZ have collided with the northern South America margin, either obliquely or directly during the Cretaceous or during the Cenozoic, and (2) those in which the island arc rocks now in the CARIB-SOAM PBZ collided with the west coast of South America during the Cretaceous and were transferred to the northern margin by transform motion during the Cenozoic. Magnetic anomalies were first rotated in the Central and South Atlantic, holding Africa fixed to establish how much NOAM had converged on SOAM during the Cenozoic. WSW convergence was discovered to have been accommodated in the northern boundary of the CARIB. There is no evidence of convergence in the form of Cenozoic island arc igneous rocks on the north coast of South America. Those results are consistent only with models of Class (2) that call for transform movement of material that had collided with the west coast of South America along the CARIB-SOAM PBZ on the northern margin of South America. 40Ar/39Ar ages of island arc rocks from northern Venezuela were found to be older than ca 70 Ma, which is consistent with a requirement of models of Class (2) that those rocks are from an island arc which collided with the west coast of South America during Cretaceous times. Testing that conclusion using data from Ecuador, Colombia, Venezuela, the Netherlands Antilles, Trinidad and Tobago has led to the construction of a new ribbon continent model of the northwestern Cordillera of South America. Because the part of the ribbon continent on the north coast of South America has been experiencing substantial deformation in the Maracaibo block during the past 10 m.y., structures in that body have had to be

  8. Imaging Lithospheric Structure beneath the Indian continent

    NASA Astrophysics Data System (ADS)

    Maurya, S.; Montagner, J. P.; Mangalampally, R. K.; Stutzmann, E.; Burgos, G.; Kumar, P.; Davuluri, S.

    2015-12-01

    The lithospheric structure and thickness to the LAB are the most debated issues, especially beneath continents. In this context, the structure and thickness of the Indian lithosphere has been controversial. Paleomagnetic data reveals that the Indian continent moved northwards at exceptionally high speeds (18-20 cm/year) and subsequently slowed down to 4-5 cm/year after its collision with Asia ≈40 Myr ago. This super mobility has been explained by an unusually thin Indian lithosphere (≈100 km; Kumar et al., 2007) in contradiction with the thick lithosphere that commonly underlies old cratonic nuclei. It is pertinent to note that the thermobarometric estimates on the ultramafic xenoliths from 65 Myr kimberlites of the Central India (Babu et al. 2009) suggest an approximately 175 km thick lithosphere. Also, recent results of P and S wave travel time tomography of India suggest that the lithospheric roots are not uniformly thick on a regional scale. Although high velocity roots typical of Precambrian shields are preserved beneath a few cratons of the Indian shield, they seem to have suffered attrition, in the plume ravaged regions like the NDVP and the Southern SGT (Singh et al., 2014). We assembled a new massive surface wave database towards obtaining 3D isotropic and anisotropic models for the Indian sub-continent, using surface waves. This necessitated processing of data from more than 500 seismic broadband stations across India and surrounding regions. Surface waves group and phase dispersion measurements are performed in a broad frequency range (16-250s). Our phase velocity anomaly maps recover most of the known geological structures. The cratons are associated with high velocity (4-6%) anomalies till 200 sec, with the WDC being faster than the EDC. Slow velocities in NW India and very high velocity anomalies (6-8%) beneath the central part of the Indo-Gangetic plains are possibly associated with the subducting Indian lithosphere. The LAB depths inferred from

  9. Redistribution of Lunar Polar Water to Mid-latitudes and Its Role in Forming an OH Veneer

    NASA Technical Reports Server (NTRS)

    Farrell, William M.; Hurley, D. M.; Hodges, R. R.; Killen, R. M.; Halekas, J. S.; Zimmerman, M. I.; Delory, G. T.

    2013-01-01

    We suggest that energization processes like ion sputtering and impact vaporization can eject/release polar water molecules residing within cold trapped regions with sufficient velocity to allow their redistribution to mid-latitudes. We consider the possibility that these polar-ejected molecules can contribution to the water/OH veneer observed as a 3 micrometer IR absorption feature at mid-latitudes by Chandrayaan-1, Cassini, and EPOXI. We find this source cannot fully account for the observed IR feature, but could be a low intensity additional source.

  10. Rechargeable dental adhesive with calcium phosphate nanoparticles for long-term ion release

    PubMed Central

    Zhang, Ling; Weir, Michael D.; Hack, Gary; Fouad, Ashraf F.; Xu, Hockin H. K.

    2015-01-01

    Objectives The tooth-resin bond is the weak link of restoration, with secondary caries as a main reason for failure. Calcium phosphate-containing resins are promising for remineralization; however, calcium (Ca) and phosphate (P) ion releases last only a couple of months. The objectives of this study were to develop the first rechargeable CaP bonding agent and investigate the key factors that determine CaP ion recharge and re-release. Methods Nanoparticles of amorphous calcium phosphate (NACP) were synthesized. Pyromellitic glycerol dimethacrylate (PMGDM), ethoxylated bisphenol-A dimethacrylate (EBPADMA), 2-hydroxyethyl methacrylate (HEMA), and bisphenol-A glycidyl dimethacrylate (BisGMA) were used to synthesize three adhesives (denoted PE, PEH and PEHB). NACP were mixed into adhesive at 0–30% by mass. Dentin shear bond strengths were measured. Adhesive specimens were tested for Ca and P initial ion release. Then the ion-exhausted specimens were immersed in Ca and P solution to recharge the specimens, and the recharged specimens were then used to measure ion re-release for 7 days as one cycle. Then these specimens were again recharged and the re-release was measured for 7 days as the second cycle. Three recharge/re-release cycles were tested. Results PEHB had the highest dentin bond strength (p<0.05). Increasing NACP content from 0 to 30% did not affect dentin bond strength (p>0.1), but increased CaP release and re-release (p<0.05). PEHB-NACP had the greatest recharge/re-release, and PE-NACP had the least (p<0.05). Ion release remained high and did not decrease with increasing the number of recharge/re-release cycles (p>0.1). After the third cycle, specimens without further recharge had continuous CaP ion release for 2–3 weeks. Significance Rechargeable CaP bonding agents were developed for the first time to provide long-term Ca and P ions to promote remineralization and reduce caries. Incorporation of NACP into adhesive had no negative effect on dentin bond

  11. Deformable registration of CT and cone-beam CT with local intensity matching.

    PubMed

    Park, Seyoun; Plishker, William; Quon, Harry; Wong, John; Shekhar, Raj; Lee, Junghoon

    2017-02-07

    Cone-beam CT (CBCT) is a widely used intra-operative imaging modality in image-guided radiotherapy and surgery. A short scan followed by a filtered-backprojection is typically used for CBCT reconstruction. While data on the mid-plane (plane of source-detector rotation) is complete, off-mid-planes undergo different information deficiency and the computed reconstructions are approximate. This causes different reconstruction artifacts at off-mid-planes depending on slice locations, and therefore impedes accurate registration between CT and CBCT. In this paper, we propose a method to accurately register CT and CBCT by iteratively matching local CT and CBCT intensities. We correct CBCT intensities by matching local intensity histograms slice by slice in conjunction with intensity-based deformable registration. The correction-registration steps are repeated in an alternating way until the result image converges. We integrate the intensity matching into three different deformable registration methods, B-spline, demons, and optical flow that are widely used for CT-CBCT registration. All three registration methods were implemented on a graphics processing unit for efficient parallel computation. We tested the proposed methods on twenty five head and neck cancer cases and compared the performance with state-of-the-art registration methods. Normalized cross correlation (NCC), structural similarity index (SSIM), and target registration error (TRE) were computed to evaluate the registration performance. Our method produced overall NCC of 0.96, SSIM of 0.94, and TRE of 2.26 → 2.27 mm, outperforming existing methods by 9%, 12%, and 27%, respectively. Experimental results also show that our method performs consistently and is more accurate than existing algorithms, and also computationally efficient.

  12. Deformable registration of CT and cone-beam CT with local intensity matching

    NASA Astrophysics Data System (ADS)

    Park, Seyoun; Plishker, William; Quon, Harry; Wong, John; Shekhar, Raj; Lee, Junghoon

    2017-02-01

    Cone-beam CT (CBCT) is a widely used intra-operative imaging modality in image-guided radiotherapy and surgery. A short scan followed by a filtered-backprojection is typically used for CBCT reconstruction. While data on the mid-plane (plane of source-detector rotation) is complete, off-mid-planes undergo different information deficiency and the computed reconstructions are approximate. This causes different reconstruction artifacts at off-mid-planes depending on slice locations, and therefore impedes accurate registration between CT and CBCT. In this paper, we propose a method to accurately register CT and CBCT by iteratively matching local CT and CBCT intensities. We correct CBCT intensities by matching local intensity histograms slice by slice in conjunction with intensity-based deformable registration. The correction-registration steps are repeated in an alternating way until the result image converges. We integrate the intensity matching into three different deformable registration methods, B-spline, demons, and optical flow that are widely used for CT-CBCT registration. All three registration methods were implemented on a graphics processing unit for efficient parallel computation. We tested the proposed methods on twenty five head and neck cancer cases and compared the performance with state-of-the-art registration methods. Normalized cross correlation (NCC), structural similarity index (SSIM), and target registration error (TRE) were computed to evaluate the registration performance. Our method produced overall NCC of 0.96, SSIM of 0.94, and TRE of 2.26 → 2.27 mm, outperforming existing methods by 9%, 12%, and 27%, respectively. Experimental results also show that our method performs consistently and is more accurate than existing algorithms, and also computationally efficient.

  13. Maritime Continent seasonal climate biases in AMIP experiments of the CMIP5 multimodel ensemble

    NASA Astrophysics Data System (ADS)

    Toh, Ying Ying; Turner, Andrew G.; Johnson, Stephanie J.; Holloway, Christopher E.

    2018-02-01

    The fidelity of 28 Coupled Model Intercomparison Project phase 5 (CMIP5) models in simulating mean climate over the Maritime Continent in the Atmospheric Model Intercomparison Project (AMIP) experiment is evaluated in this study. The performance of AMIP models varies greatly in reproducing seasonal mean climate and the seasonal cycle. The multi-model mean has better skill at reproducing the observed mean climate than the individual models. The spatial pattern of 850 hPa wind is better simulated than the precipitation in all four seasons. We found that model horizontal resolution is not a good indicator of model performance. Instead, a model's local Maritime Continent biases are somewhat related to its biases in the local Hadley circulation and global monsoon. The comparison with coupled models in CMIP5 shows that AMIP models generally performed better than coupled models in the simulation of the global monsoon and local Hadley circulation but less well at simulating the Maritime Continent annual cycle of precipitation. To characterize model systematic biases in the AMIP runs, we performed cluster analysis on Maritime Continent annual cycle precipitation. Our analysis resulted in two distinct clusters. Cluster I models are able to capture both the winter monsoon and summer monsoon shift, but they overestimate the precipitation; especially during the JJA and SON seasons. Cluster II models simulate weaker seasonal migration than observed, and the maximum rainfall position stays closer to the equator throughout the year. The tropics-wide properties of these clusters suggest a connection between the skill of simulating global properties of the monsoon circulation and the skill of simulating the regional scale of Maritime Continent precipitation.

  14. Is there any difference in pelvic floor muscles performance between continent and incontinent women?

    PubMed

    Burti, Juliana Schulze; Hacad, Claudia R; Zambon, João Paulo; Polessi, Emily Assis; Almeida, Fernando G

    2015-08-01

    To compare pelvic floor muscles (PFMs) performance in women with and without stress urinary incontinence (SUI) during endurance test. It is a prospective case-control clinical trial. After determining PFM maximal voluntary contraction (MVC) by electromyography (EMG), women underwent endurance test, which consisted of consecutively PFM 1-sec fast contractions reaching MVC amplitude followed by 1-sec rest. Training time guided by Borg perceived exertion scale was noted. Heart rate (HR) behavior and EMG variables were assessed before and after training making a physiological analysis in both groups. A total of 56 women, mean age 52.19 years old, were evaluated (26 continent and 30 incontinent women). The time that SUI and continent women took to reach fatigue (Borg 10) was 9.1 ± 4.7 and 14.19 ± 8.32 min, respectively (P = 0.006). Confirming that all women performed similar effort during the test, analysis of variance with repeated measures showed that during the endurance test both groups presented similar increase in HR, showing detectable and significant increase from resting time to Borg 10 (P < 0.001). Besides, there was similar behavior in EMG for continent and SUI women, with a decrease from the baseline resting amplitude (P = 0.003 for SUI women and P = 0.006 for continent women). Women with SUI showed worse performance during an endurance test than continent women. It suggests that women have different capacity to perform PFM training. An initial evaluation based on PFM performance would help to define the best individualized PFM training. © 2014 Wiley Periodicals, Inc.

  15. Mid-Infrared Frequency-Agile Dual-Comb Spectroscopy

    NASA Astrophysics Data System (ADS)

    Luo, Pei-Ling; Yan, Ming; Iwakuni, Kana; Millot, Guy; Hänsch, Theodor W.; Picqué, Nathalie

    2016-06-01

    We demonstrate a new approach to mid-infrared dual-comb spectroscopy. It opens up new opportunities for accurate real-time spectroscopic diagnostics and it significantly simplifies the technique of dual-comb spectroscopy. Two mid-infrared frequency combs of slightly different repetition frequencies and moderate, but rapidly tunable, spectral span are generated in the 2800-3200 cm-1 region. The generators rely on electro-optic modulators, nonlinear fibers for spectral broadening and difference frequency generation and do not involve mode-locked lasers. Flat-top frequency combs span up to 10 cm-1 with a comb line spacing of 100 MHz (3×10-3 cm-1). The performance of the spectrometer without any phase-lock electronics or correction scheme is illustrated with spectra showing resolved comb lines and Doppler-limited spectra of methane. High precision on the spectroscopic parameter (line positions and intensities) determination is demonstrated for spectra measured on a millisecond time scale and it is validated with comparison with literature data. G. Millot, S. Pitois, M. Yan, T. Hovannysyan, A. Bendahmane, T.W. Hänsch, N. Picqué, Frequency-agile dual-comb spectroscopy, Nature Photonics 10, 27-30 (2016).

  16. Anthelmintic resistance in sheep farms: update of the situation in the American continent.

    PubMed

    Torres-Acosta, J F J; Mendoza-de-Gives, P; Aguilar-Caballero, A J; Cuéllar-Ordaz, J A

    2012-09-30

    The present paper reviews the frequency of anthelmintic resistance in sheep farms in different countries of the American continent and describes some aspects that might influence the trend in sheep farms. The situation of anthelmintic resistance in sheep farms has been explored mainly in south of the continent (Argentina, Brazil and Uruguay) where sheep farming is an important industry. In those three countries, as well as in Paraguay, the first comprehensive surveys of anthelmintic resistance were performed among countries in the continent, which showed evidence of high frequency of sheep farms with anthelmintic resistance. Today, it is common to find sheep flocks with multiple-resistant worms. In North and Central America, a similar situation has been reported in sheep farms in the south of the United States of America, parts of Mexico and Costa Rica. On the other hand, other areas of the continent show low frequency of farms with anthelmintic resistance. From many areas no results have been published regarding situation on anthelmintic resistance or, alternatively, published results have received limited dissemination. Although the diagnosis of anthelmintic resistance is important for decision making of helminth management/control at the farm level, this is still an aspiration rather than a reality. For decades, researchers working on anthelmintic resistance in the American continent have expressed the need to change farmers' attitudes towards anthelmintic drugs. A common advice has been to check the anthelmintic drug efficacy regularly and reduce the dependence on these with alternative control measures. In spite of such advice, the challenge to stop/delay the advancement of anthelmintic resistance against the available anthelmintic drugs is still present. The evidence suggests that anthelmintic resistance is a growing phenomenon in the American continent. The situation described might be the tip of the iceberg, as anthelmintic resistance is still largely under

  17. [Continent colostomy and colon irrigation].

    PubMed

    Kostov, D; Temelkov, T; Kiriazov, E; Ivanov, K; Ignatov, V; Kobakov, G

    2000-01-01

    The authors have studied a functional activity of a continent colostomy at 20 patients, undergone an abdomeno-perineal extirpation of rectum and carried out periodic colonirrigations, during a period of 6 months. A conus type, closed irrigating system has been used. The degree of an incontinency at patients has been compared before and after the beginning of the colonirrigations. The irrigating procedures have reduced spontaneous defications at patients during a week 28 times and have improved the quality of life significantly. The application of colostomy bags has been restricted in 8 (40%) patients. An intraluminal ultrasonographic investigation has been done at 12 (60%) patients at the end of 6 month irrigating period. No changes of the ultrasonographic image of the precolostomic segment of colon has been observed.

  18. Social Network and Content Analysis of the North American Carbon Program as a Scientific Community of Practice

    NASA Technical Reports Server (NTRS)

    Brown, Molly E.; Ihli, Monica; Hendrick, Oscar; Delgado-Arias, Sabrina; Escobar, Vanessa M.; Griffith, Peter

    2015-01-01

    The North American Carbon Program (NACP) was formed to further the scientific understanding of sources, sinks, and stocks of carbon in Earth's environment. Carbon cycle science integrates multidisciplinary research, providing decision-support information for managing climate and carbon-related change across multiple sectors of society. This investigation uses the conceptual framework of com-munities of practice (CoP) to explore the role that the NACP has played in connecting researchers into a carbon cycle knowledge network, and in enabling them to conduct physical science that includes ideas from social science. A CoP describes the communities formed when people consistently engage in shared communication and activities toward a common passion or learning goal. We apply the CoP model by using keyword analysis of abstracts from scientific publications to analyze the research outputs of the NACP in terms of its knowledge domain. We also construct a co-authorship network from the publications of core NACP members, describe the structure and social pathways within the community. Results of the content analysis indicate that the NACP community of practice has substantially expanded its research on human and social impacts on the carbon cycle, contributing to a better understanding of how human and physical processes interact with one another. Results of the co-authorship social network analysis demonstrate that the NACP has formed a tightly connected community with many social pathways through which knowledge may flow, and that it has also expanded its network of institutions involved in carbon cycle research over the past seven years.

  19. High-harmonic generation in ZnO driven by self-compressed mid-infrared pulses

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gholam-Mirzaei, Shima; Beetar, John E.; Chacon, Alexis

    Progress in attosecond science has relied on advancements in few-cycle pulse generation technology and its application to high-order harmonic generation. Traditionally, self-phase modulation in bulk solids has been used for the compression of moderate-energy pulses, additionally exhibiting favorable dispersion properties for mid-infrared (mid-IR) pulses. For this study, we use the anomalous dispersion of Y 3Al 5O 12 (YAG) to self-compress many-cycle pulses from a 50 kHz mid-IR OPA down to produce sub-three-cycle 10 μJ pulses and further use them to generate high-order harmonics in a ZnO crystal. In agreement with theoretical predictions, we observe a boost in the harmonic yieldmore » by a factor of two, and spectral broadening of above-gap harmonics, compared to longer driving pulses. The enhanced yield results from an increase in the intensity for the self-compressed pulses.« less

  20. High-harmonic generation in ZnO driven by self-compressed mid-infrared pulses

    DOE PAGES

    Gholam-Mirzaei, Shima; Beetar, John E.; Chacon, Alexis; ...

    2018-02-20

    Progress in attosecond science has relied on advancements in few-cycle pulse generation technology and its application to high-order harmonic generation. Traditionally, self-phase modulation in bulk solids has been used for the compression of moderate-energy pulses, additionally exhibiting favorable dispersion properties for mid-infrared (mid-IR) pulses. For this study, we use the anomalous dispersion of Y 3Al 5O 12 (YAG) to self-compress many-cycle pulses from a 50 kHz mid-IR OPA down to produce sub-three-cycle 10 μJ pulses and further use them to generate high-order harmonics in a ZnO crystal. In agreement with theoretical predictions, we observe a boost in the harmonic yieldmore » by a factor of two, and spectral broadening of above-gap harmonics, compared to longer driving pulses. The enhanced yield results from an increase in the intensity for the self-compressed pulses.« less

  1. OxyContin® as Currency: OxyContin® Use and Increased Social Capital among Rural Appalachian Drug Users

    PubMed Central

    Jonas, Adam B.; Young, April M.; Oser, Carrie B.; Leukefeld, Carl G.; Havens, Jennifer R.

    2012-01-01

    Studies have shown that position within networks of social relations can have direct implications on the health behaviors of individuals. The present study examines connections between drug use and individual social capital within social networks of drug users (n=503) from rural Appalachian Kentucky, U.S.A. Respondent driven sampling was used to recruit individuals age 18 and older who had used one of the following drugs to get high: cocaine, crack, heroin, methamphetamine, or prescription opioids. Substance use was measured via self-report and social network analysis of participants’ drug use network was used to compute effective size, a measure of social capital. Drug network ties were based on sociometric data on recent (past 6 month) drug co-usage. Multivariate multi-level ordinal regression was used to model the independent effect of sociodemographic and drug use characteristics on social capital. Adjusting for gender, income, and education, daily OxyContin® use was found to be significantly associated with greater social capital, and daily marijuana use was associated with less social capital. These results suggest that in regions with marked economic disparities such as rural Appalachia, OxyContin® may serve as a form of currency that is associated with increased social capital among drug users. Interventions focusing on increasing alternate pathways to acquiring social capital may be one way in which to alleviate the burden of drug use in this high-risk population. PMID:22465379

  2. Responding to University Policies and Initiatives: The Role of Reflexivity in the Mid-Career Academic

    ERIC Educational Resources Information Center

    Brew, Angela; Boud, David; Lucas, Lisa; Crawford, Karin

    2017-01-01

    How do academics make sense of university policies and strategic initiatives and act on them? Interviews were conducted with 27 mid-career academics in different disciplines, different research-intensive university environments and two countries (England and Australia). Data were analysed iteratively utilising a critical realist perspective,…

  3. Perforated peptic ulcer disease: mid-term outcome among Iranian population.

    PubMed

    Kamani, Freshteh; Moghimi, Mehrdad; Marashi, Seyed Ali; Peyrovi, Habibollah; Sheikhvatan, Mehrdad

    2010-06-01

    The aim of this study was to evaluate midterm outcome of patients with perforated peptic ulcer disease and to determine the main predictors of mid-term mortality. Demographic and clinical characteristics of 56 patients with the diagnosis of perforated peptic ulcer who were hospitalized in Taleghani Hospital over a 10-year period (19962005) were retrospectively collected, and in-hospital mortality and morbidity were determined. Patients were also followed for one month, one year and five years after the operation. Among these patients, 85.5% were treated with omental patch closure, 7.1% underwent vagotomy pyloroplasty, 5.3% underwent concurrent vagotomy and gastrojejunostomy, and 1.8% underwent antrectomy. In-hospital mortality and morbidity were 5.3% and 48.2%, respectively. Survival rates at one month, one year and five years after the operation were 92.9%, 89.3% and 78.6%, respectively. Advanced age (p=0.001), preoperative shock (p=0.003), history of malignancy before surgery (p=0.001), treatment delay (p=0.028), intensive care unit admission (p=0.032), and size of ulcer >5 cm (p=0.043) were the main predictors of five-year mortality in the followed patients. Mid-term mortality of treated perforated peptic ulcer disease among our population was notable, and the main predictors of mortality included advanced age, history of malignancy, treatment delay, intensive care unit admission, and ulcer size.

  4. Analysis of the Environmental Management System based on ISO 14001 on the American continent.

    PubMed

    Neves, Fábio de Oliveira; Salgado, Eduardo G; Beijo, Luiz A

    2017-09-01

    The American continent is in broad economic and industrial development. Consequently, a more detailed discussion of the impacts generated by such development is needed. Moreover, there is an increase in the number of ISO 14001 certificates issued to this continent. Given the above, no studies were found that bridge the gap to identify the influence of different factors on ISO 14001 in the Americas. Thus, this article has as its main aim to check which economic, environmental and cultural factors have influence on ISO 14001 Certification in the American Continent. The data were collected in the ISO Survey, World Bank, United Nations Development Programme and International Energy Agency. Among the countries of that continent, thirteen were analyzed and only two did not show the economic factors as the influence factor in the multiple regression models fitted with Brazil and the United State. In these models, all presented environmental factors as influencing factors. Only in Brazil the index HDI presented as cultural factor in multiple regression model fitted. The economic factors: Gross Domestic Product and exports of goods and services and environmental: Carbon Dioxide (CO 2 ) and fossil fuel consumption were the most influential in ISO 14001 certification. Venezuela, Uruguay, Colombia and the United States were countries that had factors dependent on each other, featuring the environmental marketing. Briefly, this study brings up several implications: to the academy, with the proposal of new concepts and guidance on the factors that assist in ISO 14001 certification in the American Continent. Additionally, taking into account the industry, the factors serve as efficiency parameters for the implementation of ISO 14001 standard, and for the Government to improve through factors that do not fit in multiple regression models. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Changes in self assessment of continence status between telephone survey and subsequent clinical visit

    PubMed Central

    Thomas, A; Kane Low, L; Tumbarello, JA; Miller, JM; Fenner, DE; DeLancey, JOL

    2012-01-01

    AIMS To explore variance in reporting continence information obtained by telephone survey with face-to-face clinician interview in a clinical setting. METHODS As part of a cross-sectional, epidemiologic study of incontinence prevalence among Black and White women ages 35-64 years, randomly selected households were contacted from geographic areas of known racial composition. Of 2814 women who completed a 20-minute, 137-item telephone interview, 1702 were invited for future components of the study. A subset of these women was recruited for a clinical evaluation that was conducted within a mean of 82 days (SD 38 days) following the interviews. Prior to urodynamics testing, a clinician interview was conducted inquiring about continence status. The criterion for incontinence for both the telephone interview and the clinician interview was constant: twelve or more episodes of incontinence per year. Women whose subjective reports of continence information differed between telephone and clinician interviews were designated as “switchers”. RESULTS Of the 394 women (222 Black, 172 White) who completed the clinical portion, 24.6% (n=97) were switchers. Switchers were four times more likely to change from continent to incontinent (80.4% N=78) than from incontinent to continent (19.4%; N=19 p=.000) and nearly three times more likely to be Black (69% N=67) than White (31%; N=30 p=.001). Telephone qualitative interviews were completed with 72 of the switchers. The primary reason for switching was changes in women’s life circumstances such as variation in seasons, activities of daily living, and health status followed by increased awareness of leakage secondary to the phone interview. CONCLUSION One-time subjective telephone interviews assessing incontinence symptoms may underestimate the prevalence of incontinence especially among Black women. PMID:19816917

  6. Parallel Evolution of Copy-Number Variation across Continents in Drosophila melanogaster

    PubMed Central

    Schrider, Daniel R.; Hahn, Matthew W.; Begun, David J.

    2016-01-01

    Genetic differentiation across populations that is maintained in the presence of gene flow is a hallmark of spatially varying selection. In Drosophila melanogaster, the latitudinal clines across the eastern coasts of Australia and North America appear to be examples of this type of selection, with recent studies showing that a substantial portion of the D. melanogaster genome exhibits allele frequency differentiation with respect to latitude on both continents. As of yet there has been no genome-wide examination of differentiated copy-number variants (CNVs) in these geographic regions, despite their potential importance for phenotypic variation in Drosophila and other taxa. Here, we present an analysis of geographic variation in CNVs in D. melanogaster. We also present the first genomic analysis of geographic variation for copy-number variation in the sister species, D. simulans, in order to investigate patterns of parallel evolution in these close relatives. In D. melanogaster we find hundreds of CNVs, many of which show parallel patterns of geographic variation on both continents, lending support to the idea that they are influenced by spatially varying selection. These findings support the idea that polymorphic CNVs contribute to local adaptation in D. melanogaster. In contrast, we find very few CNVs in D. simulans that are geographically differentiated in parallel on both continents, consistent with earlier work suggesting that clinal patterns are weaker in this species. PMID:26809315

  7. Multifunctional Information Distribution System (MIDS)

    DTIC Science & Technology

    2013-12-01

    Arlington VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law, no person shall be subject to a penalty for failing to...Estimate DoD - Department of Defense DSN - Defense Switched Network Econ - Economic Eng - Engineering Est - Estimating FMS - Foreign Military Sales FY...fighter aircraft, bombers, helicopters, ships, and ground sites . The MIDS Program consists of the MIDS Low Volume Terminal (MIDS-LVT) and the MIDS

  8. A study on the birth and globalization of sports originated from each continent.

    PubMed

    Lee, Byung Jin; Kim, Tae Young

    2016-02-01

    The purpose of this research is to see how continent specific sports rose to its modern-day status through globalization. This research focuses on the historical background of how England's football, America's national pastime, baseball, Japan's Judo, and Korea's Taekwondo developed into sports in addition to the reasoning behind its globalization. Promoted by England and the rest of the European continent, Soccer is considered to be one of the world's most popular sports and has served its function as a form of cultural imperialism. It has also advanced alongside commerce, missionary work and other types of cultural clashes. In America, baseball was used to integrate its multicultural society and developed so that the team captain leads the rest of his team. The sports of Oriental countries were reborn through modernization that was influenced by the modern rationality, education etc. of its Western counterparts. Judo and Taekwondo were introduced globally through the Olympic Games. As mentioned above the birth of sporting events has a close connection to a nation's cultural background and globalization has taken different forms depending on which continent it originated from.

  9. High-Speed Stark Wavelength Tuning of MidIR Interband Cascade Lasers

    DTIC Science & Technology

    2007-03-15

    STARK WAVELENGTH TUNING OF MidIR ICLs 361 Fig. 2. Lasing spectra of the tunable ICL at different bias currents. injection region at before tunneling ...the energy separation between and (and hence the emission wavelength) undergoes a linear Stark shift that depends on the bias current which controls...response Fig. 3. Lasing spectra of the tunable ICL at different bias modulation frequen- cies. Fig. 4. Dependence of the intensity of the Line 2 on bias

  10. Selection of the NIR region for a regression model of the ethanol concentration in fermentation process by an online NIR and mid-IR dual-region spectrometer and 2D heterospectral correlation spectroscopy.

    PubMed

    Nishii, Takashi; Genkawa, Takuma; Watari, Masahiro; Ozaki, Yukihiro

    2012-01-01

    A new selection procedure of an informative near-infrared (NIR) region for regression model building is proposed that uses an online NIR/mid-infrared (mid-IR) dual-region spectrometer in conjunction with two-dimensional (2D) NIR/mid-IR heterospectral correlation spectroscopy. In this procedure, both NIR and mid-IR spectra of a liquid sample are acquired sequentially during a reaction process using the NIR/mid-IR dual-region spectrometer; the 2D NIR/mid-IR heterospectral correlation spectrum is subsequently calculated from the obtained spectral data set. From the calculated 2D spectrum, a NIR region is selected that includes bands of high positive correlation intensity with mid-IR bands assigned to the analyte, and used for the construction of a regression model. To evaluate the performance of this procedure, a partial least-squares (PLS) regression model of the ethanol concentration in a fermentation process was constructed. During fermentation, NIR/mid-IR spectra in the 10000 - 1200 cm(-1) region were acquired every 3 min, and a 2D NIR/mid-IR heterospectral correlation spectrum was calculated to investigate the correlation intensity between the NIR and mid-IR bands. NIR regions that include bands at 4343, 4416, 5778, 5904, and 5955 cm(-1), which result from the combinations and overtones of the C-H group of ethanol, were selected for use in the PLS regression models, by taking the correlation intensity of a mid-IR band at 2985 cm(-1) arising from the CH(3) asymmetric stretching vibration mode of ethanol as a reference. The predicted results indicate that the ethanol concentrations calculated from the PLS regression models fit well to those obtained by high-performance liquid chromatography. Thus, it can be concluded that the selection procedure using the NIR/mid-IR dual-region spectrometer combined with 2D NIR/mid-IR heterospectral correlation spectroscopy is a powerful method for the construction of a reliable regression model.

  11. Responses of Mean and Extreme Precipitation to Deforestation in the Maritime Continent

    NASA Astrophysics Data System (ADS)

    Chen, C. C.; Lo, M. H.; Yu, J. Y.

    2017-12-01

    Anthropogenic land use and land cover change, including tropical deforestation, could have substantial effects on local surface energy and water budgets, and thus on the atmospheric stability which may result in changes in precipitation. Maritime Continent has undergone severe deforestation in recent decades but has received less attention than Amazon or Congo rainforests. Therefore, this study is to decipher the precipitation response to deforestation in the Maritime Continent. We conduct deforestation experiments using Community Earth System Model (CESM) and through converting the tropical rainforest into grassland. The results show that deforestation in Maritime Continent leads to an increase in both mean temperature and mean precipitation. Moisture budget analysis indicates that the increase in precipitation is associated with the vertically integrated vertical moisture advection, especially the dynamic component (changes in convection). In addition, through moist static energy (MSE) budget analysis, we find the atmosphere among deforested areas become unstable owing to the combined effects of positive specific humidity anomalies at around 850 hPa and anomalous warming extended from the surface to 750 hPa. This instability will induce anomalous ascending motion, which could enhance the low-level moisture convergence, providing water vapor from the surrounding warm ocean. To further evaluate the precipitation response to deforestation, we examine the precipitation changes under La Niña events and global warming scenario using CESM Atmospheric Model Intercomparison Project (AMIP) simulations and Representative Concentration Pathway (RCP) 8.5 simulations. We find that the precipitation increase caused by deforestation in Maritime Continent is comparable in magnitude to that generated by either natural variability or global warming forcing. Besides the changes in mean precipitation, preliminary results show the extreme precipitation also increases. We will further

  12. Gondwana to Asia: Plate tectonics, paleogeography and the biological connectivity of the Indian sub-continent from the Middle Jurassic through latest Eocene (166 35 Ma)

    NASA Astrophysics Data System (ADS)

    Ali, Jason R.; Aitchison, Jonathan C.

    2008-06-01

    Using the most up-to-the-date information available, we present a considerably revised plate tectonic and paleogeographic model for the Indian Ocean bordering continents, from Gondwana's Middle Jurassic break-up through to India's collision with Asia in the middle Cenozoic. The landmass framework is then used to explore the sometimes complex and occasionally counter-intuitive patterns that have been observed in the fossil and extant biological records of India, Madagascar, Africa and eastern Eurasia, as well those of the more distal continents. Although the paleogeographic model confirms the traditional view that India became progressively more isolated from the major landmasses during the Cretaceous and Paleocene, it is likely that at various times minor physiographic features (principally ocean islands) provided causeways and/or stepping-stone trails along which land animals could have migrated to/from the sub-continent. Aside from a likely link (albeit broken by several marine gaps) to Africa for much of this time (it is notable, that the present-day/recent biota of Madagascar indicates that the ancestors of five land-mammal orders, plus bats, crossed the > 400-km-wide Mozambique Channel at different times in the Cenozoic), it is possible that the Kerguelen Plateau connected India and Australia-Antarctica in the mid-Cretaceous (approximately 115-90 Ma). Later, the Seychelles-Mascarene Plateau and nearby elevated sea-floor areas could have allowed faunas to pass between southern India and Madagascar in the Late Cretaceous, from around 85-65 Ma, with an early Cenozoic extension to this path forming as a result of the Reunion hot-spot trace islands growing on the ocean floor to the SSW of India. The modelling also suggests that India's northward passage towards Asia, with eventual collision at 35 Ma, involved the NE corner of the sub-continent making a glancing contact with Sumatra, followed by Burma from ~ 57 Ma (late Paleocene) onwards, a scenario which is

  13. Correlated multielectron dynamics in mid-infrared laser pulse interactions with neon atoms.

    PubMed

    Tang, Qingbin; Huang, Cheng; Zhou, Yueming; Lu, Peixiang

    2013-09-09

    The multielectron dynamics in nonsequential triple ionization (NSTI) of neon atoms driven by mid-infrared (MIR) laser pulses is investigated with the three-dimensional classical ensemble model. In consistent with the experimental result, our numerical result shows that in the MIR regime, the triply charged ion longitudinal momentum spectrum exhibits a pronounced double-hump structure at low laser intensity. Back analysis reveals that as the intensity increases, the responsible triple ionization channels transform from direct (e, 3e) channel to the various mixed channels. This transformation of the NSTI channels leads to the results that the shape of ion momentum spectra becomes narrow and the distinct maxima shift towards low momenta with the increase of the laser intensity. By tracing the triply ionized trajectories, the various ionization channels at different laser intensities are clearly identified and these results provide an insight into the complex dynamics of the correlated three electrons in NSTI.

  14. Characterization Methods for Small Estuarine Systems in the Mid-Atlantic Region of the United States

    EPA Science Inventory

    Various statistical methods were applied to spatially discrete data from 14 intensively sampled small estuarine systems in the mid-Atlantic U.S. The number of sites per system ranged from 6 to 37. The surface area of the systems ranged from 1.9 to 193.4 km2. Parameters examined ...

  15. Mid-Infrared Reflectance Imaging of Thermal-Barrier Coatings

    NASA Technical Reports Server (NTRS)

    Edlridge, Jeffrey I.; Martin, Richard E.

    2009-01-01

    An apparatus for mid-infrared reflectance imaging has been developed as means of inspecting for subsurface damage in thermal-barrier coatings (TBCs). The apparatus is designed, more specifically, for imaging the progression of buried delamination cracks in plasma-sprayed yttria-stabilized zirconia coatings on turbine-engine components. Progression of TBC delamination occurs by the formation of buried cracks that grow and then link together to produce eventual TBC spallation. The mid-infrared reflectance imaging system described here makes it possible to see delamination progression that is invisible to the unaided eye, and therefore give sufficiently advanced warning before delamination progression adversely affects engine performance and safety. The apparatus (see figure) includes a commercial mid-infrared camera that contains a liquid-nitrogen-cooled focal plane indium antimonide photodetector array, and imaging is restricted by a narrow bandpass centered at wavelength of 4 microns. This narrow wavelength range centered at 4 microns was chosen because (1) it enables avoidance of interfering absorptions by atmospheric OH and CO2 at 3 and 4.25 microns, respectively; and (2) the coating material exhibits maximum transparency in this wavelength range. Delamination contrast is produced in the midinfrared reflectance images because the introduction of cracks into the TBC creates an internal TBC/air-gap interface with a high diffuse reflectivity of 0.81, resulting in substantially higher reflectance of mid-infrared radiation in regions that contain buried delamination cracks. The camera is positioned a short distance (.12 cm) from the specimen. The mid-infrared illumination is generated by a 50-watt silicon carbide source positioned to the side of the mid-infrared camera, and the illumination is collimated and reflected onto the specimen by a 6.35-cm-diameter off-axis paraboloidal mirror. Because the collected images are of a steady-state reflected intensity (in

  16. [Anorectal continence following manual and mechanical anastomosis suture. Results of a controlled study of rectal surgery].

    PubMed

    Jostarndt, L; Thiede, A; Lau, G; Hamelmann, H

    1984-06-01

    In a controlled clinical trial-manual vs. stapler anastomosis in rectal surgery-it was found that both suture techniques per se made no difference in the function of anal continence. The anal pressures at rest and sphincter contraction remained unchanged. A linear reduction of functional reservoir of the "neorectum" could be shown, which depended on the level and healing of the anastomosis. An anastomosis level at 6 cm from anocutaneous line is important for functional reasons. Anastomoses above this level do not cause any consequences for anal continence. Anastomoses below this level result in a reduced functional reservoir for at least 6 months. Within this period a decrease in anal continence is possible, especially in cases of disturbed healing of the anastomosis.

  17. Ph-activated nano-amorphous calcium phosphate-based cement to reduce dental enamel demineralization.

    PubMed

    Melo, Mary A S; Weir, Michael D; Passos, Vanara F; Powers, Michael; Xu, Hockin H K

    2017-12-01

    Enamel demineralization is destructive, esthetically compromised, and costly complications for orthodontic patients. Nano-sized amorphous calcium phosphate (NACP) has been explored to address this challenge. The 20% NACP-loaded ortho-cement notably exhibited favorable behavior on reducing demineralization of enamel around brackets in a caries model designed to simulate the carious attack. The 20% NACP-loaded ortho-cement markedly promotes higher calcium and phosphate release at a low pH, and the mineral loss was almost two fold lower and carious lesion depth decreased the by 1/3. This novel approach is promising co-adjuvant route for prevention of dental caries dissemination in millions of patients under orthodontic treatment.

  18. Mid-Life Career Influence

    ERIC Educational Resources Information Center

    Heald, James E.

    1977-01-01

    Events common to all people, although in differing degrees, such as physiological and technological changes at mid-life, constitute important influences on career change and development in the mid-life period. (Author)

  19. Pattern recognition receptor-mediated cytokine response in infants across 4 continents.

    PubMed

    Smolen, Kinga K; Ruck, Candice E; Fortuno, Edgardo S; Ho, Kevin; Dimitriu, Pedro; Mohn, William W; Speert, David P; Cooper, Philip J; Esser, Monika; Goetghebuer, Tessa; Marchant, Arnaud; Kollmann, Tobias R

    2014-03-01

    Susceptibility to infection as well as response to vaccination varies among populations. To date, the underlying mechanisms responsible for these clinical observations have not been fully delineated. Because innate immunity instructs adaptive immunity, we hypothesized that differences between populations in innate immune responses may represent a mechanistic link to variation in susceptibility to infection or response to vaccination. Determine whether differences in innate immune responses exist among infants from different continents of the world. We determined the innate cytokine response following pattern recognition receptor (PRR) stimulation of whole blood from 2-year-old infants across 4 continents (Africa, North America, South America, and Europe). We found that despite the many possible genetic and environmental exposure differences in infants across 4 continents, innate cytokine responses were similar for infants from North America, South America, and Europe. However, cells from South African infants secreted significantly lower levels of cytokines than did cells from infants from the 3 other sites, and did so following stimulation of extracellular and endosomal but not cytosolic PRRs. Substantial differences in innate cytokine responses to PRR stimulation exist among different populations of infants that could not have been predicted. Delineating the underlying mechanism(s) for these differences will not only aid in improving vaccine-mediated protection but possibly also provide clues for the susceptibility to infection in different regions of the world. Copyright © 2013 The Authors. Published by Mosby, Inc. All rights reserved.

  20. Strong-field physics with mid-infrared lasers

    NASA Astrophysics Data System (ADS)

    Pogorelsky, I. V.

    2002-04-01

    Mid-infrared gas laser technology promises to become a unique tool for research in strong-field relativistic physics. The degree to which physics is relativistic is determined by a ponderomotive potential. At a given intensity, a 10 μm wavelength CO2 laser reaches a 100 times higher ponderomotive potential than the 1 μm wavelength solid state lasers. Thus, we can expect a proportional increase in the throughput of such processes as laser acceleration, x-ray production, etc. These arguments have been confirmed in proof-of-principle Thomson scattering and laser acceleration experiments conducted at BNL and UCLA where the first terawatt-class CO2 lasers are in operation. Further more, proposals for the 100 TW, 100 fs CO2 lasers based on frequency-chirped pulse amplification have been conceived. Such lasers can produce physical effects equivalent to a hypothetical multi-petawatt solid state laser. Ultra-fast mid-infrared lasers will open new routes to the next generation electron and ion accelerators, ultra-bright monochromatic femtosecond x-ray and gamma sources, allow to attempt the study of Hawking-Unruh radiation, and explore relativistic aspects of laser-matter interactions. We review the present status and experiments with terawatt-class CO2 lasers, sub-petawatt projects, and prospective applications in strong-field science. .

  1. Mid-Shelf Hardground Fish Habitats off the Georgia Coast

    NASA Astrophysics Data System (ADS)

    Platt, M.; Sautter, L.

    2016-02-01

    Multibeam sonar data were collected off the Georgia coast aboard the R/V Savannah by the College of Charleston BEAMS Program in May 2015. Kongsberg EM2040C data were post-processed in CARIS HIPS and SIPS 9.0 to create bathymetric maps overlain with backscatter intensity. The mid-shelf focus sites lie at depths between 25 and 40 m, and include the northern edge of Gray's Reef National Marine Sanctuary. The study sites are known areas of abundant fish congregations, identified by the South Carolina Department of Natural Resources' Marine Resources Monitoring, Assessment, & Prediction (MARMAP) program. The regional mid-shelf seafloor morphology consists of sand ridges, rock outcrops, and incised meandering channels 1 to 3 m deep. Backscatter analysis was used to identify hardground structures that might provide habitat for a high diversity of vertebrates and invertebrates. Multiple hardground structures were found and characterized at these locations and will be targeted for further research and possible inclusion in the Georgia and South Carolina continental shelf Marine Protected Areas.

  2. Characterization of protein and carbohydrate mid-IR spectral features in crop residues

    NASA Astrophysics Data System (ADS)

    Xin, Hangshu; Zhang, Yonggen; Wang, Mingjun; Li, Zhongyu; Wang, Zhibo; Yu, Peiqiang

    2014-08-01

    To the best of our knowledge, a few studies have been conducted on inherent structure spectral traits related to biopolymers of crop residues. The objective of this study was to characterize protein and carbohydrate structure spectral features of three field crop residues (rice straw, wheat straw and millet straw) in comparison with two crop vines (peanut vine and pea vine) by using Fourier transform infrared spectroscopy (FTIR) technique with attenuated total reflectance (ATR). Also, multivariate analyses were performed on spectral data sets within the regions mainly related to protein and carbohydrate in this study. The results showed that spectral differences existed in mid-IR peak intensities that are mainly related to protein and carbohydrate among these crop residue samples. With regard to protein spectral profile, peanut vine showed the greatest mid-IR band intensities that are related to protein amide and protein secondary structures, followed by pea vine and the rest three field crop straws. The crop vines had 48-134% higher spectral band intensity than the grain straws in spectral features associated with protein. Similar trends were also found in the bands that are mainly related to structural carbohydrates (such as cellulosic compounds). However, the field crop residues had higher peak intensity in total carbohydrates region than the crop vines. Furthermore, spectral ratios varied among the residue samples, indicating that these five crop residues had different internal structural conformation. However, multivariate spectral analyses showed that structural similarities still exhibited among crop residues in the regions associated with protein biopolymers and carbohydrate. Further study is needed to find out whether there is any relationship between spectroscopic information and nutrition supply in various kinds of crop residue when fed to animals.

  3. Characterization of protein and carbohydrate mid-IR spectral features in crop residues.

    PubMed

    Xin, Hangshu; Zhang, Yonggen; Wang, Mingjun; Li, Zhongyu; Wang, Zhibo; Yu, Peiqiang

    2014-08-14

    To the best of our knowledge, a few studies have been conducted on inherent structure spectral traits related to biopolymers of crop residues. The objective of this study was to characterize protein and carbohydrate structure spectral features of three field crop residues (rice straw, wheat straw and millet straw) in comparison with two crop vines (peanut vine and pea vine) by using Fourier transform infrared spectroscopy (FTIR) technique with attenuated total reflectance (ATR). Also, multivariate analyses were performed on spectral data sets within the regions mainly related to protein and carbohydrate in this study. The results showed that spectral differences existed in mid-IR peak intensities that are mainly related to protein and carbohydrate among these crop residue samples. With regard to protein spectral profile, peanut vine showed the greatest mid-IR band intensities that are related to protein amide and protein secondary structures, followed by pea vine and the rest three field crop straws. The crop vines had 48-134% higher spectral band intensity than the grain straws in spectral features associated with protein. Similar trends were also found in the bands that are mainly related to structural carbohydrates (such as cellulosic compounds). However, the field crop residues had higher peak intensity in total carbohydrates region than the crop vines. Furthermore, spectral ratios varied among the residue samples, indicating that these five crop residues had different internal structural conformation. However, multivariate spectral analyses showed that structural similarities still exhibited among crop residues in the regions associated with protein biopolymers and carbohydrate. Further study is needed to find out whether there is any relationship between spectroscopic information and nutrition supply in various kinds of crop residue when fed to animals. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Evaluation of Model Performance over the Maritime Continent

    NASA Astrophysics Data System (ADS)

    Reynolds, C. A.; Barton, N. P.; Chen, S.; Flatau, M. K.; Ridout, J. A.; Janiga, M.; Jensen, T.; Richman, J. G.; Metzger, E. J.; Baranowski, D.

    2017-12-01

    The introduction of high-resolution global coupled models holds promise for extended-range (subseasonal to seasonal) prediction of high-impact weather. While forecast models have shown considerable improvement in the prediction of tropical phenomena on these timescales, specifically in the simulation and prediction of the Madden-Julian Oscillation (MJO), obstacles remain. In particular, many models still have difficulty accurately simulating the propagation of the MJO over the maritime continent. This has been hypothesized, at least in part, to be related to deficiencies in simulating the diurnal cycle over this region, which in turn is dependent on accurate representation of fine-scale atmosphere-ocean-land interactions, orography, and atmospheric convection. These issues have motivated the international Year of Maritime Continent (YMC) effort and the Office of Naval Research Propagation of Intra-Seasonal Tropical Oscillations (PISTON) initiative. In preparation for YMC and PISTON, we closely evaluate the performance of the Navy Earth System Model (NESM), a coupled global forecast model, in representing the diurnal cycle and other prominent phenomena in the maritime continent region. NESM performance is compared with stand-alone atmospheric simulations with prescribed fixed and analyzed sea surface temperatures (SSTs). Initial results from the Dynamics of the Madden-Julian Oscillation field phase (Fall 2011) period indicate that NESM is able to capture the precipitation day-time maximum over land and night-time maximum over ocean, but day-time precipitation over Borneo, Sumatra and the Malay Peninsula is too strong as compared to TRMM observations. The simulation of low-level winds qualitatively captures sea and land breeze patterns as compared with ERA-Interim analysis, with quantitative biases varying by island. The fully-coupled system and the stand-alone atmospheric model simulations are more similar to each other than to the observations, indicating that

  5. Abuse of reformulated OxyContin: Updated findings from a sentinel surveillance sample of individuals assessed for substance use disorder.

    PubMed

    Cassidy, Theresa A; Thorley, Eileen; Black, Ryan A; DeVeaugh-Geiss, Angela; Butler, Stephen F; Coplan, Paul

    To examine abuse prevalence for OxyContin and comparator opioids over a 6-year period prior to and following market entry of reformulated OxyContin and assess consistency in abuse across treatment settings and geographic regions. An observational study examining longitudinal changes using cross-sectional data from treatment centers for substance use disorder. A total of 874 facilities in 39 states in the United States within the National Addictions Vigilance Intervention and Prevention Program (NAVIPPRO®) surveillance system. Adults (72,060) assessed for drug problems using the Addiction Severity Index-Multimedia Version (ASI-MV®) from January 2009 through December 2015 who abused prescription opioids. Percent change in past 30-day abuse. OxyContin had significantly lower abuse 5 years after reformulation compared to levels for original OxyContin. Consistency of magnitude in OxyContin abuse reductions across geographic regions, ranging from 41 to 52 percent with differences in abuse reductions in treatment setting categories occurred. Changes in geographic region and treatment settings across study years did not bias the estimate of lower OxyContin abuse through confounding. In the postmarket setting, limitations and methodologic challenges in abuse measurement exist and it is difficult to isolate singular impacts of any one intervention given the complexity of prescription opioid abuse. Expectations for a reasonable threshold of abuse for any one ADF product or ADF opioids as a class are still uncertain and undefined. A significant decline in abuse prevalence of reformulated OxyContin was observed 5 years after its reformulation among this treatment sample of individuals assessed for substance use disorder that was lower historically for the original formulation of this product.

  6. Mid-IR enhanced laser ablation molecular isotopic spectrometry

    NASA Astrophysics Data System (ADS)

    Brown, Staci; Ford, Alan; Akpovo, Codjo A.; Johnson, Lewis

    2016-08-01

    A double-pulsed laser-induced breakdown spectroscopy (DP-LIBS) technique utilizing wavelengths in the mid-infrared (MIR) for the second pulse, referred to as double-pulse LAMIS (DP-LAMIS), was examined for its effect on detection limits compared to single-pulse laser ablation molecular isotopic spectrometry (LAMIS). A MIR carbon dioxide (CO2) laser pulse at 10.6 μm was employed to enhance spectral emissions from nanosecond-laser-induced plasma via mid-IR reheating and in turn, improve the determination of the relative abundance of isotopes in a sample. This technique was demonstrated on a collection of 10BO and 11BO molecular spectra created from enriched boric acid (H3BO3) isotopologues in varying concentrations. Effects on the overall ability of both LAMIS and DP-LAMIS to detect the relative abundance of boron isotopes in a starting sample were considered. Least-squares fitting to theoretical models was used to deduce plasma parameters and understand reproducibility of results. Furthermore, some optimization for conditions of the enhanced emission was achieved, along with a comparison of the overall emission intensity, plasma density, and plasma temperature generated by the two techniques.

  7. Simulation of Glacial Cycles Before and After the Mid-Pleistocene Transition

    NASA Astrophysics Data System (ADS)

    Ganopolski, A.; Willeit, M.; Calov, R.

    2017-12-01

    In spite of significant progress achieved in understanding of glacial cycles, the cause of Mid-Pleistocene transition (MPT) is still not fully understood. To study possible mechanisms of the MPT we used the Earth system model of intermediate complexity CLIMBER-2 which incorporates all major components of the Earth system - atmosphere, ocean, land surface, northern hemisphere ice sheets, terrestrial biota and soil carbon, aeolian dust and marine biogeochemistry. We run the model through the entire Quaternary. The only prescribed forcing in these simulations is variations in Earth orbital parameters. In addition we prescribed gradually evolving in time terrestrial sediment cover and global volcanic outgassing. We found that gradual removal of terrestrial sediment from the Northern Hemisphere continent by glacial processes is sufficient to explain transition from 40-ka to 100-ka worlds around 1 million years ago. By starting the model at different times and using the same initial conditions we found that modeling results converge to the same solution which depends only on the orbital forcing and lower boundary conditions. Our results thus strongly suggest that Quaternary glacial cycles are externally forced and nearly deterministic.

  8. The Diurnal Cycle over the Maritime Continent and its Interaction with the MJO

    NASA Astrophysics Data System (ADS)

    Matthews, A. J.; Peatman, S.; Baranowski, D. B.; Stevens, D. P.; Heywood, K. J.; Flatau, P. J.; Schmidtko, S.

    2014-12-01

    The complex land-sea distribution and topography of the maritime continent acts to disrupt or even completely block the eastward propagation of the Madden-Julian Oscillation (MJO) from the Indian Ocean to the western Pacific. This leads to changes in tropical latent heat release and subsequent impacts on global circulation. Convection over the maritime continent is dominated by the diurnal cycle. Where the mean diurnal cycle is strong (over the islands and surrounding seas), 80% of the MJO precipitation signal in the maritime continent is accounted for by changes in the amplitude of the diurnal cycle. The canonical view of the MJO as the smooth eastward propagation of a large-scale precipitation envelope also breaks down over the islands of the Maritime Continent. Instead, a vanguard of precipitation jumps ahead of the main body by approximately 6 days or 2000 km. Hence, there can be enhanced precipitation over Sumatra, Borneo or New Guinea when the large-scale MJO envelope over the surrounding ocean is one of suppressed precipitation. This behaviour is discussed in terms of an interaction between the diurnal cycle and the MJO circulation. The diurnal cycle is also strong in the ocean. Seaglider measurements taken during the CINDY/DYNAMO campaign show the existence of a diurnal warm layer in the upper few metres of the ocean. This has a significant effect on the surface fluxes, of an order of Watts per square metre. The diurnal warm layer is favoured during the inactive phase of the MJO and may act to help precondition the atmosphere to convection. The activities of the MJO Task Force and Subseasonal to Seasonal Prediction project will be discussed in this context.

  9. First results from a full-waveform inversion of the African continent using Salvus

    NASA Astrophysics Data System (ADS)

    van Herwaarden, D. P.; Afanasiev, M.; Krischer, L.; Trampert, J.; Fichtner, A.

    2017-12-01

    We present the initial results from an elastic full-waveform inversion (FWI) of the African continent which is melded together within the framework of the Collaborative Seismic Earth Model (CSEM) project. The continent of Africa is one of the most geophysically interesting regions on the planet. More specifically, Africa contains the Afar Depression, which is the only place on Earth where incipient seafloor spreading is sub-aerially exposed, along with other anomalous features such as the topography in the south, and several smaller surface expressions such as the Cameroon Volcanic Line and Congo Basin. Despite its significance, relatively few tomographic images exist of Africa, and, as a result, the debate on the geophysical origins of Africa's anomalies is rich and ongoing. Tomographic images of Africa present unique challenges due to uneven station coverage: while tectonically active areas such as the Afar rift are well sampled, much of the continent exhibits a severe lack of seismic stations. And, while Africa is mostly surrounded by tectonically active spreading plate boundaries, the interior of the continent is seismically quiet. To mitigate such issues, our simulation domain is extended to include earthquakes occurring in the South Atlantic and along the western edge of South America. Waveform modelling and inversion is performed using Salvus, a flexible and high-performance software suite based on the spectral-element method. Recently acquired recordings from the AfricaArray and NARS seismic networks are used to complement data obtained from global networks. We hope that this new model presents a fresh high-resolution image of African geodynamic structure, and helps advance the debate regarding the causative mechanisms of its surface anomalies.

  10. CONTIN XPCS: Software for Inverse Transform Analysis of X-Ray Photon Correlation Spectroscopy Dynamics

    PubMed Central

    Narayanan, Suresh; Zhang, Fan; Kuzmenko, Ivan; Ilavsky, Jan

    2018-01-01

    X-ray photon correlation spectroscopy (XPCS) and dynamic light scattering (DLS) both reveal dynamics using coherent scattering, but X-rays permit investigating of dynamics in a much more diverse array of materials. Heterogeneous dynamics occur in many such materials, and we showed how classic tools employed in analysis of heterogeneous DLS dynamics extend to XPCS, revealing additional information that conventional Kohlrausch exponential fitting obscures. This work presents the software implementation of inverse transform analysis of XPCS data called CONTIN XPCS, an extension of traditional CONTIN that accommodates dynamics encountered in equilibrium XPCS measurements. PMID:29875507

  11. CONTIN XPCS: Software for Inverse Transform Analysis of X-Ray Photon Correlation Spectroscopy Dynamics.

    PubMed

    Andrews, Ross N; Narayanan, Suresh; Zhang, Fan; Kuzmenko, Ivan; Ilavsky, Jan

    2018-02-01

    X-ray photon correlation spectroscopy (XPCS) and dynamic light scattering (DLS) both reveal dynamics using coherent scattering, but X-rays permit investigating of dynamics in a much more diverse array of materials. Heterogeneous dynamics occur in many such materials, and we showed how classic tools employed in analysis of heterogeneous DLS dynamics extend to XPCS, revealing additional information that conventional Kohlrausch exponential fitting obscures. This work presents the software implementation of inverse transform analysis of XPCS data called CONTIN XPCS, an extension of traditional CONTIN that accommodates dynamics encountered in equilibrium XPCS measurements.

  12. Next-generation mid-infrared sources

    NASA Astrophysics Data System (ADS)

    Jung, D.; Bank, S.; Lee, M. L.; Wasserman, D.

    2017-12-01

    The mid-infrared (mid-IR) is a wavelength range with a variety of technologically vital applications in molecular sensing, security and defense, energy conservation, and potentially in free-space communication. The recent development and rapid commercialization of new coherent mid-infrared sources have spurred significant interest in the development of mid-infrared optical systems for the above applications. However, optical systems designers still do not have the extensive optical infrastructure available to them that exists at shorter wavelengths (for instance, in the visible and near-IR/telecom wavelengths). Even in the field of optoelectronic sources, which has largely driven the growing interest in the mid-infrared, the inherent limitations of state-of-the-art sources and the gaps in spectral coverage offer opportunities for the development of new classes of lasers, light emitting diodes and emitters for a range of potential applications. In this topical review, we will first present an overview of the current state-of-the-art mid-IR sources, in particular thermal emitters, which have long been utilized, and the relatively new quantum- and interband-cascade lasers, as well as the applications served by these sources. Subsequently, we will discuss potential mid-infrared applications and wavelength ranges which are poorly served by the current stable of mid-IR sources, with an emphasis on understanding the fundamental limitations of the current source technology. The bulk of the manuscript will then explore both past and recent developments in mid-infrared source technology, including narrow bandgap quantum well lasers, type-I and type-II quantum dot materials, type-II superlattices, highly mismatched alloys, lead-salts and transition-metal-doped II-VI materials. We will discuss both the advantages and limitations of each of the above material systems, as well as the potential new applications which they might serve. All in all, this topical review does not aim

  13. A study on the birth and globalization of sports originated from each continent

    PubMed Central

    Lee, Byung Jin; Kim, Tae Young

    2016-01-01

    The purpose of this research is to see how continent specific sports rose to its modern-day status through globalization. This research focuses on the historical background of how England’s football, America’s national pastime, baseball, Japan’s Judo, and Korea’s Taekwondo developed into sports in addition to the reasoning behind its globalization. Promoted by England and the rest of the European continent, Soccer is considered to be one of the world’s most popular sports and has served its function as a form of cultural imperialism. It has also advanced alongside commerce, missionary work and other types of cultural clashes. In America, baseball was used to integrate its multicultural society and developed so that the team captain leads the rest of his team. The sports of Oriental countries were reborn through modernization that was influenced by the modern rationality, education etc. of its Western counterparts. Judo and Taekwondo were introduced globally through the Olympic Games. As mentioned above the birth of sporting events has a close connection to a nation’s cultural background and globalization has taken different forms depending on which continent it originated from. PMID:26933653

  14. Introital ultrasonography: a comparison of women with stress incontinence due to urethral hypermobility and continent women.

    PubMed

    Cassadó, Jordi; Pessarrodona, Antoni; Tulleuda, Raquel; Cabero, Lluís; Valls, Marta; Quintana, Salvador; Rodríguez-Carballeira, Mónica

    2006-10-01

    To determine if there is a variable on introital ultrasonography (IUS) that can be used to distinguish between women with stress urinary incontinence (SUI) due to urethral hypermobility (UH) and continent women. This single-centre, prospective, blind, cohort, observational study comprised 383 women (245 continent and 138 incontinent) who were all appropriately informed volunteers selected according to the inclusion criteria. IUS with a convex probe was performed on all women; the measurement plane was standardized and coordinates were obtained at rest and on straining. Several distances were measured to determine if any provided an objective distinction between continent and incontinent women. Among all the IUS variables assessed, sliding (calculated as the difference between the distance urethra-bladder neck, U-BN, at rest and under stress) was the best for distinguishing continent and incontinent women. The receiver operating characteristic curves showed that with a threshold of 8 mm, sliding had a sensitivity of 92% and a specificity of 79.6% for detecting SUI due to UH. The distances symphysis-urethra (S-U) and U-BN at rest could also discriminate, but with lower significance. IUS is an important tool for diagnosing SUI; there are three independent variables, one dynamic (sliding) and two static (distances S-U and U-BN), that can be used to distinguish between continent women and those with SUI due to UH. Sliding is the most reliable, as it has the highest sensitivity and specificity. We think that the simplicity, low financial cost and reliability of IUS could allow it to be a routine procedure for physicians working in incontinence units.

  15. The development of a physiotherapy continence promotion program using a customer focus.

    PubMed

    Chiarelli, Pauline; Cockburn, Jill

    1999-01-01

    Health promotion programs provide information, education for health and opportunity for the development of the skills that people need to make healthy choices. The current climate of health care practice also directs its focus to the needs and wants of the health care consumers. This entails active input from the target group. The present study used focus groups in an attempt to ensure input from women in early postpartum into the development of a postpartum continence promotion program. The focus groups revealed anomalies in women's perceived susceptibility to, and knowledge about, urinary incontinence and pelvic floor exercises, while highlighting other areas of need. Focus groups proved an invaluable tool in the development of a more effective physiotherapy continence promotion program.

  16. Jupiter's Mid-Infrared Aurora: Solar Connection and Minor Constituents

    NASA Technical Reports Server (NTRS)

    Kostiuk, Theodore; Livengood, T.A.; Fast, K.E.; Hewagama, T.; Schmilling, F.; Sonnabend, G.; Delgado, J.

    2009-01-01

    High spectral resolution in the 12 pin region of the polar regions of Jupiter reveal unique information on auroral phenomena and upper stratospheric composition. Polar aurorae in Jupiter's atmosphere radiate; throughout the electromagnetic spectrum from X-ray through mid-infrared (mid-IR, 5 - 20 micron wavelength). Voyager IRIS data and ground-based. spectroscopic measurements of Jupiter's northern mid-IR aurora acquired since 1982, reveal a correlation between auroral brightness and solar activity that has not been observed in Jovian aurora at other wavelengths. Over nearly three solar cycles, Jupiter auroral ethane, emission brightness and solar 10.7-cm radar flux and sunspot number are positively correlated with high confidence. Ethane line emission intensity varies over tenfold between low and high scalar activity periods. Detailed measurements have been made using the GSFC HIPWAC spectrometer at the NASA IRTF since the last solar maximum, following the mid-IR emission through the declining phase toward solar minimum. An even more convincing correlation with solar activity is evident in these data. The spectra measured contain features that cannot be attributed to ethane and are most likely spectra of minor constituents whose molecular bands overlap the v9 band of ethane. Possible candidates are allene, propane, and other higher order hydrocarbons. These features appear to be enhanced in the active polar regions. Laboratory measurements at comparable spectral resolution of spectra of candidate molecules will be used to identify the constituents. Current analyses of these results will be described, including planned measurements on polar ethane line emission scheduled through the rise of the next solar maximum beginning in 2009, with a steep gradient to a maximum in 2012. This work is relevant to the Juno mission and to the development of the NASA/ESA Europa Jupiter System Mission.

  17. Towards the mid-infrared optical biopsy

    NASA Astrophysics Data System (ADS)

    Seddon, Angela B.; Benson, Trevor M.; Sujecki, Slawomir; Abdel-Moneim, Nabil; Tang, Zhuoqi; Furniss, David; Sojka, Lukasz; Stone, Nick; Jayakrupakar, Nallala; Lloyd, Gavin R.; Lindsay, Ian; Ward, Jon; Farries, Mark; Moselund, Peter M.; Napier, Bruce; Lamrini, Samir; Møller, Uffe; Kubat, Irnis; Petersen, Christian R.; Bang, Ole

    2016-03-01

    We are establishing a new paradigm in mid-infrared molecular sensing, mapping and imaging to open up the midinfrared spectral region for in vivo (i.e. in person) medical diagnostics and surgery. Thus, we are working towards the mid-infrared optical biopsy (`opsy' look at, bio the biology) in situ in the body for real-time diagnosis. This new paradigm will be enabled through focused development of devices and systems which are robust, functionally designed, safe, compact and cost effective and are based on active and passive mid-infrared optical fibers. In particular, this will enable early diagnosis of external cancers, mid-infrared detection of cancer-margins during external surgery for precise removal of diseased tissue, in one go during the surgery, and mid-infrared endoscopy for early diagnosis of internal cancers and their precision removal. The mid-infrared spectral region has previously lacked portable, bright sources. We set a record in demonstrating extreme broad-band supercontinuum generated light 1.4 to 13.3 microns in a specially engineered, high numerical aperture mid-infrared optical fiber. The active mid-infrared fiber broadband supercontinuum for the first time offers the possibility of a bright mid-infrared wideband source in a portable package as a first step for medical fiber-based systems operating in the mid-infrared. Moreover, mid-infrared molecular mapping and imaging is potentially a disruptive technology to give improved monitoring of the environment, energy efficiency, security, agriculture and in manufacturing and chemical processing. This work is in part supported by the European Commission: Framework Seven (FP7) Large-Scale Integrated Project MINERVA: MId-to-NEaR- infrared spectroscopy for improVed medical diAgnostics (317803; www.minerva-project.eu).

  18. Evolutionary conservatism and convergence both lead to striking similarity in ecology, morphology and performance across continents in frogs.

    PubMed

    Moen, Daniel S; Irschick, Duncan J; Wiens, John J

    2013-12-22

    Many clades contain ecologically and phenotypically similar species across continents, yet the processes generating this similarity are largely unstudied, leaving fundamental questions unanswered. Is similarity in morphology and performance across assemblages caused by evolutionary convergence or by biogeographic dispersal of evolutionarily conserved ecotypes? Does convergence to new ecological conditions erase evidence of past adaptation? Here, we analyse ecology, morphology and performance in frog assemblages from three continents (Asia, Australia and South America), assessing the importance of dispersal and convergent evolution in explaining similarity across regions. We find three striking results. First, species using the same microhabitat type are highly similar in morphology and performance across both clades and continents. Second, some species on different continents owe their similarity to dispersal and evolutionary conservatism (rather than evolutionary convergence), even over vast temporal and spatial scales. Third, in one case, an ecologically specialized ancestor radiated into diverse ecotypes that have converged with those on other continents, largely erasing traces of past adaptation to their ancestral ecology. Overall, our study highlights the roles of both evolutionary conservatism and convergence in explaining similarity in species traits over large spatial and temporal scales and demonstrates a statistical framework for addressing these questions in other systems.

  19. Evolutionary conservatism and convergence both lead to striking similarity in ecology, morphology and performance across continents in frogs

    PubMed Central

    Moen, Daniel S.; Irschick, Duncan J.; Wiens, John J.

    2013-01-01

    Many clades contain ecologically and phenotypically similar species across continents, yet the processes generating this similarity are largely unstudied, leaving fundamental questions unanswered. Is similarity in morphology and performance across assemblages caused by evolutionary convergence or by biogeographic dispersal of evolutionarily conserved ecotypes? Does convergence to new ecological conditions erase evidence of past adaptation? Here, we analyse ecology, morphology and performance in frog assemblages from three continents (Asia, Australia and South America), assessing the importance of dispersal and convergent evolution in explaining similarity across regions. We find three striking results. First, species using the same microhabitat type are highly similar in morphology and performance across both clades and continents. Second, some species on different continents owe their similarity to dispersal and evolutionary conservatism (rather than evolutionary convergence), even over vast temporal and spatial scales. Third, in one case, an ecologically specialized ancestor radiated into diverse ecotypes that have converged with those on other continents, largely erasing traces of past adaptation to their ancestral ecology. Overall, our study highlights the roles of both evolutionary conservatism and convergence in explaining similarity in species traits over large spatial and temporal scales and demonstrates a statistical framework for addressing these questions in other systems. PMID:24174109

  20. Cooling and exhumation of continents at billion-year time scales

    NASA Astrophysics Data System (ADS)

    Blackburn, T.; Bowring, S. A.; Perron, T.; Mahan, K. H.; Dudas, F. O.

    2011-12-01

    Hat Block collided at ~1.8 Ga. Rutile U-Pb data from multiple xenoliths, each exhumed from a different depth within the crustal column reveal a range of dates that varies as a function of xenolith residence depth. The shallowest mid- to lower crustal xenoliths (~25 km) cooled first, yielding the youngest dates and yet cooled at rates between 0.1-0.25 °C/Ma over 500 My or more. Deeper xenoliths record cooling at progressively younger times at similar rates and time-scales. From orogony to eruption of xenoliths onto the surface, the lithospheric thermal history constructed using this technique may exceed a billion years. Combining this cooling history with a lithosphere thermal model yields an estimate for the average integrated rate of craton erosion between 0.00-<0.0025 km/Ma across the orogen; a range far lower than the geologically recent to present day rates for continental erosion (<0.005-0.1 km/Ma). This marks the first ever determination of continental exhumation rates on time-scales that approach the age of the continents themselves and has implications for secular cooling of the asthenosphere.

  1. Prolapse and continence surgery in countries of the Organization for Economic Cooperation and Development in 2012.

    PubMed

    Haya, Nir; Baessler, Kaven; Christmann-Schmid, Corina; de Tayrac, Renaud; Dietz, Viviane; Guldberg, Rikke; Mascarenhas, Teresa; Nussler, Emil; Ballard, Emma; Ankardal, Maud; Boudemaghe, Thierry; Wu, Jennifer M; Maher, Christopher F

    2015-06-01

    The purpose of this study was to report the rates and types of pelvic organ prolapse (POP) and female continence surgery performed in member countries of the Organization for Economic Co-operation and Development (OECD) in 2012. The published health outcome data sources of the 34 OECD countries were contacted for data on POP and female continence interventions from 2010-2012. In nonresponding countries, data were sought from national or insurer databases. Extracted data were entered into an age-specific International Classification of Disease, edition 10 (ICD-10)-compliant Excel spreadsheet by 2 authors independently in English-speaking countries and a single author in non-English-speaking countries. Data were collated centrally and discrepancies were resolved by mutual agreement. We report on 684,250 POP and 410,352 continence procedures that were performed in 15 OECD countries in 2012. POP procedures (median rate, 1.38/1000 women; range, 0.51-2.55 prolapse procedures/1000 women) were performed 1.8 times more frequently than continence procedures (median rate, 0.75/1000 women; range, 0.46-1.65 continence procedures/1000 women). Repairs of the anterior vaginal compartment represented 54% of POP procedures; posterior repairs represented 43% of the procedures, and apical compartment repairs represented 20% of POP procedures. Median rate of graft usage was 15.7% of anterior vaginal repairs (range, 3.3-25.6%) and 8.5% (range, 3.2-17%) of posterior vaginal repairs. Apical compartment repairs were repaired vaginally at a median rate of 70% (range, 35-95%). Sacral colpopexy represented a median rate of 17% (range, 5-65%) of apical repairs; 61% of sacral colpopexies were performed minimally invasively. Between 2010 and 2012, there was a 3.7% median reduction in transvaginal grafts, a 4.0% reduction in midurethral slings, and a 25% increase in sacral colpopexies that were performed per 1000 women. Midurethral slings represented 82% of female continence surgeries. The 5

  2. Citizen scientists analyzing tropical cyclone intensities

    NASA Astrophysics Data System (ADS)

    Hennon, Christopher C.

    2012-10-01

    A new crowd sourcing project called CycloneCenter enables the public to analyze historical global tropical cyclone (TC) intensities. The primary goal of CycloneCenter, which launched in mid-September, is to resolve discrepancies in the recent global TC record arising principally from inconsistent development of tropical cyclone intensity data. The historical TC record is composed of data sets called "best tracks," which contain a forecast agency's best assessment of TC tracks and intensities. Best track data have improved in quality since the beginning of the geostationary satellite era in the 1960s (because TCs could no longer disappear from sight). However, a global compilation of best track data (International Best Track Archive for Climate Stewardship (IBTrACS)) has brought to light large interagency differences between some TC best track intensities, even in the recent past [Knapp et al., 2010Knapp et al., 2010]. For example, maximum wind speed estimates for Tropical Cyclone Gay (1989) differed by as much as 70 knots as it was tracked by three different agencies.

  3. Rare, Intense, Big fires dominate the global tropics under drier conditions.

    PubMed

    Hantson, Stijn; Scheffer, Marten; Pueyo, Salvador; Xu, Chi; Lasslop, Gitta; van Nes, Egbert H; Holmgren, Milena; Mendelsohn, John

    2017-10-30

    Wildfires burn large parts of the tropics every year, shaping ecosystem structure and functioning. Yet the complex interplay between climate, vegetation and human factors that drives fire dynamics is still poorly understood. Here we show that on all continents, except Australia, tropical fire regimes change drastically as mean annual precipitation falls below 550 mm. While the frequency of fires decreases below this threshold, the size and intensity of wildfires rise sharply. This transition to a regime of Rare-Intense-Big fires (RIB-fires) corresponds to the relative disappearance of trees from the landscape. Most dry regions on the globe are projected to become substantially drier under global warming. Our findings suggest a global zone where this drying may have important implications for fire risks to society and ecosystem functioning.

  4. Topside and ground ionosonde observations of a mid-latitude scintillation region

    NASA Astrophysics Data System (ADS)

    Hajkowicz, L. A.

    1982-02-01

    Ionospheric amplitude scintillations of transmissions in the VHF range from orbiting satellites were compared with topside and ground (bottomside) ionograms of an inhomogeneous region in southern mid-latitudes. It is evident that, for the event considered, there is a good spatial correlation between intense topside and bottomside spread-F and scintillations. The ionospheric disturbance pattern appears to agree with a quasi-sinusoidal model of frontal disturbances (derived from the angle-of-arrival experiments) in the F-region at these geographic latitudes.

  5. Use of Antegrade Continence Enema for the Treatment of Fecal Incontinence and Functional Constipation in Adults: A Systematic Review.

    PubMed

    Patel, Abhilasha S; Saratzis, Athanasios; Arasaradnam, Ramesh; Harmston, Christopher

    2015-10-01

    Antegrade continence enema is a proximal colonic stoma that allows antegrade lavage of the colon for the treatment of fecal incontinence and functional constipation. Its role in the treatment of these conditions in adults has not been established. This review aimed to evaluate the clinical response and complications of antegrade continence enema in the adult population. A systematic literature search of MEDLINE, EMBASE, and Cochrane Central Register of Controlled Trials databases from January 1980 to October 2013 was conducted. Studies reporting clinical outcomes of antegrade continence enema in adult patients were considered. Only studies with participants aged 16 years and older were selected. Use of the antegrade continence enema for the treatment of constipation and incontinence in adults was investigated. The primary outcome was the number of patients irrigating their stoma. Secondary outcomes included the incidence of stoma stenosis, assessment of functional outcome, and evaluation of quality of life. Overall, 15 studies were selected, describing outcomes in 374 patients. All of the reports were observational cross-sectional studies, and 4 were prospective. The number of participants still using their stoma ranged from 47% to 100% over a follow-up period of 6 to 55 months. Eleven studies reported achievement of full continence in 33% to 100% of patients. Four studies described functional outcomes, and 7 studies reported a wide range of patient satisfaction. The rate of stoma stenosis varied from 8% to 50%. There were considerable heterogeneities within and across studies. Most studies were of poor quality, as reflected in the Methodological Index for Nonrandomized Studies score. Antegrade continence enema has been reported as an acceptable treatment of both functional constipation and fecal incontinence in adults across several analyses. There is wide variation regarding outcome measures. Larger prospective studies are required to assess the role of antegrade

  6. Effect of mesoscale oceanic eddies on mid-latitude storm-tracks.

    NASA Astrophysics Data System (ADS)

    Foussard, Alexis; Lapeyre, Guillaume; Plougonven, Riwal

    2017-04-01

    Sharp sea surface temperature (SST) gradients associated with oceanic western boundary currents (WBC) exert an influence on the position and intensity of mid-latitude storm-tracks. This occurs through strong surface baroclinicity maintained by cross frontal SST gradient and deep vertical atmospheric motion due to convection on the warm flank of the WBC. However the additional role of mesoscale oceanic structures (30-300km) has not yet been explored although they have a non-negligible influence on surface heat fluxes. Using the Weather Research and Forecasting model, we investigate the potential role of these oceanic eddies in the case of an idealized atmospheric mid-latitude storm track forced by a mesoscale oceanic eddy field superposed with a large-scale SST gradient. Surface latent and sensible fluxes are shown to react with a non-linear response to the SST variations, providing additional heat and moisture supply at large scales. The atmospheric response is not restricted to the boundary layer but reaches the free troposphere, especially through increased water vapor vertical transport and latent heat release. This additional heating in presence of eddies is balanced by a shift of the storm-track and its poleward heat flux toward high latitudes, with amplitude depending on atmospheric configuration and eddies amplitude. We also explore how this displacement of perturbations changes the position and structure of the mid-latitude jet through eddy momentum fluxes.

  7. Emission properties of Er3+-doped Ge20Ga5Sb10Se65 glasses in near- and mid-infrared

    NASA Astrophysics Data System (ADS)

    Yang, Zhen; Pan, Hongbo; Chen, Yimin; Wang, Rongping; Shen, Xiang

    2018-03-01

    In this work, we reported the fabrications and characterization of Er3+-doped Ge20Ga5Sb10Se65 glasses and glass-ceramics and measured their transmission and fluorescence spectra. The results showed that, the fluorecence intensity of the glasses increased until Er3+ concentration was up to ∼1.1 wt% Er, and then decreased with further increasing Er3+ concentration that was due to concentration quenching effect. While it was found that the mid- and far-infrared transmission did not decrease significantly in the glasses annealed at 310 °C for a duration up to 50 h, seven-folded enhancement in the intensity of mid-infrared fluorescence at 2.78 μm was observed. This demonstrated the potentials of the materials used for Er-doped amplifier and fiber laser.

  8. Structural-geophysical model of the basement complex of the Aden-Red Sea region

    NASA Astrophysics Data System (ADS)

    Isaev, E. N.

    1987-11-01

    A relief map of the basement complex underlying the volcanogenic sedimentary cover has been constructed on the basis of composite Bouguer anomaly maps and maps of magnetic anomalies ΔT. Seismic and geological data on the Gulf of Aden and the Red Sea as well as on adjacent areas of Africa and Arabia have also been used. The mid-Red Sea and mid-Aden uplifts (similar to the mid-oceanic ones) as well as the foredeep have been identified. The thickness of cover in the foredeeps is 6-8 km. A regional negative Bouguer anomaly crosses the Aden-Red Sea rift system and includes the area of young volcanism. Intensive linear magnetic anomalies are traceable only within the area of overlap of the rift system and the zone of young volcanism. Rift system apophyses have advanced into the continent and their nature is similar to that of the Afar triangle.

  9. Why do we need detailed gravity over continents: Some Australian examples

    NASA Technical Reports Server (NTRS)

    Lambeck, K.

    1985-01-01

    Geophysical quantities available over a continent are gravity and components of the magnetic field. Direct inferences on crustal structure are difficult to make and strongly dependent on mechanical assumptions the isostatic state. The data for Australia represents one of the best continental scale gravity surveys. The gravity anomalies are generally bland over the continent which confirms that stress relaxation and erosion and rebound were instrumental in reducing nonhydrostatic stresses. In central Australia very large gravity anomalies occur and the region is out of isostatic equilibrium despite the fact that tectonic activity ceased 300 ma ago. The isostatic response functions points to a substantial horizontal compression in the crust. Similar conclusions are drawn for the large anomalies in western Australia. The tectonic implications of these anomalies are examined. In eastern Australia the gravity anomalies are explained in terms of a model of erosion of the highlands and concomitant regional isostatic rebound.

  10. Worldwide transportation directory : statistical contacts and transportation profiles by continent and country

    DOT National Transportation Integrated Search

    1997-05-01

    The Directory was created to assist transportation data users, policy makers, planners, researchers, information specialists and others in locating statistical contacts and transportation profiles in different countries. It lists, by continent, 1,925...

  11. Effect of water-ageing on dentine bond strength and anti-biofilm activity of bonding agent containing new monomer dimethylaminododecyl methacrylate

    PubMed Central

    Zhang, Ke; Cheng, Lei; Wu, Eric J.; Weir, Michael D.; Bai, Yuxing; Xu, Hockin H. K.

    2013-01-01

    Objectives The objectives of this study were to develop bonding agent containing a new antibacterial monomer dimethylaminododecyl methacrylate (DMADDM) as well as nanoparticles of silver (NAg) and nanoparticles of amorphous calcium phosphate (NACP), and to investigate the effects of water-ageing for 6 months on dentine bond strength and anti-biofilm properties for the first time. Methods Four bonding agents were tested: Scotchbond Multi-Purpose (SBMP) Primer and Adhesive control; SBMP + 5% DMADDM; SBMP + 5% DMADDM + 0.1% NAg; and SBMP + 5% DMADDM + 0.1% NAg with 20% NACP in adhesive. Specimens were water-aged for 1 d and 6 months at 37 °C. Then the dentine shear bond strengths were measured. A dental plaque microcosm biofilm model was used to inoculate bacteria on water-aged specimens and to measure metabolic activity, colony-forming units (CFUs), and lactic acid production. Results Dentine bond strength showed a 35% loss in 6 months of water-ageing for SBMP control (mean ± sd; n = 10); in contrast, the new antibacterial bonding agents showed no strength loss. The DMADDM–NAg–NACP containing bonding agent imparted a strong antibacterial effect by greatly reducing biofilm viability, metabolic activity and acid production. The biofilm CFU was reduced by more than two orders of magnitude, compared to SBMP control. Furthermore, the DMADDM–NAg–NACP bonding agent exhibited a long-term antibacterial performance, with no significant difference between 1 d and 6 months (p > 0.1). Conclusions Incorporating DMADDM–NAg–NACP in bonding agent yielded potent and long-lasting antibacterial properties, and much stronger bond strength after 6 months of water-ageing than a commercial control. The new antibacterial bonding agent is promising to inhibit biofilms and caries at the margins. The method of DMADDM–NAg–NACP incorporation may have a wide applicability to other adhesives, cements and composites. PMID:23583528

  12. Mantle flow and deforming continents, insights from the Tethys realm

    NASA Astrophysics Data System (ADS)

    Jolivet, Laurent; Faccenna, Claudio; Becker, Thorsten; Tesauro, Magdala

    2017-04-01

    Continent deformation is partly a consequence of plate motion along plate boundaries. Whether underlying asthenospheric flow can also deform continents through basal shear or push on topographic irregularities of the base of the lithosphere is an open question. Eurasia has been extending at different scales since 50 Ma, from the Mediterranean back-arc domains to extension of Asia between the India-Asia collision zone and the Pacific subduction zones. While compression at plate margins, in subduction or collision zones can propagate far within continents, the mechanism explaining extension distributed over thousands of kilometres is unclear. We use trajectories of continental plates and continental fragments since 50 Ma in different kinematic frames and compare them with various proxies of asthenospheric flow such as seismic anisotropy at various depths. These trajectories partly fit sub-lithospheric seismic anisotropy with two main circulations, one carrying Africa and Eurasia away from the large low velocity anomaly (LLSVP) underlying South and West Africa and one carrying the Pacific plate away from the LLSVP underlying the southern Pacific. Under eastern Eurasia the flow converges with the Pacific flow and distributed extension affects eastern Asia all the way to Western Pacific back-arc basins. We speculate that the flow carrying India northward and Eurasia eastward has invaded the Pacific domain and caused this widely distributed extension that interferes with the strike-slip faults issued from the Himalaya-Tibet collision zone. This model is in line with earlier propositions based on geochemical proxies. We discuss this model and compare it to other widely distributed extensional deformation episodes such as the Early Cretaceous extension of Africa and lastly propose a scheme of large-scale continental deformation in relation to underlying mantle convection at different scales.

  13. Potential effects of climate change on freshwater ecosystems of the New England/Mid-Atlantic Region

    Treesearch

    Marianne V. Moore; Michael L. Pace; John R. Mather; [and others; [Editor’s note: Patricia A. Flebbe is the SRS co-author for this publication.

    1997-01-01

    Numerous freshwater ecosystems, dense concentrations of humans along the eastern seaboard, extensive forests, and a history of intensive land use distinguish the New England/Mid-Atlantic Region. Human population densities are forecast to increase in portions of the region at the same time that climate is expected to be changing. Consequently, the effects of humans and...

  14. Parallel Evolution of Copy-Number Variation across Continents in Drosophila melanogaster.

    PubMed

    Schrider, Daniel R; Hahn, Matthew W; Begun, David J

    2016-05-01

    Genetic differentiation across populations that is maintained in the presence of gene flow is a hallmark of spatially varying selection. In Drosophila melanogaster, the latitudinal clines across the eastern coasts of Australia and North America appear to be examples of this type of selection, with recent studies showing that a substantial portion of the D. melanogaster genome exhibits allele frequency differentiation with respect to latitude on both continents. As of yet there has been no genome-wide examination of differentiated copy-number variants (CNVs) in these geographic regions, despite their potential importance for phenotypic variation in Drosophila and other taxa. Here, we present an analysis of geographic variation in CNVs in D. melanogaster. We also present the first genomic analysis of geographic variation for copy-number variation in the sister species, D. simulans, in order to investigate patterns of parallel evolution in these close relatives. In D. melanogaster we find hundreds of CNVs, many of which show parallel patterns of geographic variation on both continents, lending support to the idea that they are influenced by spatially varying selection. These findings support the idea that polymorphic CNVs contribute to local adaptation in D. melanogaster In contrast, we find very few CNVs in D. simulans that are geographically differentiated in parallel on both continents, consistent with earlier work suggesting that clinal patterns are weaker in this species. © The Author 2016. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  15. Continent-wide survey reveals massive decline in African savannah elephants

    PubMed Central

    Schlossberg, Scott; Griffin, Curtice R.; Bouché, Philippe J.C.; Djene, Sintayehu W.; Elkan, Paul W.; Ferreira, Sam; Grossman, Falk; Kohi, Edward Mtarima; Landen, Kelly; Omondi, Patrick; Peltier, Alexis; Selier, S.A. Jeanetta; Sutcliffe, Robert

    2016-01-01

    African elephants (Loxodonta africana) are imperiled by poaching and habitat loss. Despite global attention to the plight of elephants, their population sizes and trends are uncertain or unknown over much of Africa. To conserve this iconic species, conservationists need timely, accurate data on elephant populations. Here, we report the results of the Great Elephant Census (GEC), the first continent-wide, standardized survey of African savannah elephants. We also provide the first quantitative model of elephant population trends across Africa. We estimated a population of 352,271 savannah elephants on study sites in 18 countries, representing approximately 93% of all savannah elephants in those countries. Elephant populations in survey areas with historical data decreased by an estimated 144,000 from 2007 to 2014, and populations are currently shrinking by 8% per year continent-wide, primarily due to poaching. Though 84% of elephants occurred in protected areas, many protected areas had carcass ratios that indicated high levels of elephant mortality. Results of the GEC show the necessity of action to end the African elephants’ downward trajectory by preventing poaching and protecting habitat. PMID:27635327

  16. Continent-wide survey reveals massive decline in African savannah elephants.

    PubMed

    Chase, Michael J; Schlossberg, Scott; Griffin, Curtice R; Bouché, Philippe J C; Djene, Sintayehu W; Elkan, Paul W; Ferreira, Sam; Grossman, Falk; Kohi, Edward Mtarima; Landen, Kelly; Omondi, Patrick; Peltier, Alexis; Selier, S A Jeanetta; Sutcliffe, Robert

    2016-01-01

    African elephants (Loxodonta africana) are imperiled by poaching and habitat loss. Despite global attention to the plight of elephants, their population sizes and trends are uncertain or unknown over much of Africa. To conserve this iconic species, conservationists need timely, accurate data on elephant populations. Here, we report the results of the Great Elephant Census (GEC), the first continent-wide, standardized survey of African savannah elephants. We also provide the first quantitative model of elephant population trends across Africa. We estimated a population of 352,271 savannah elephants on study sites in 18 countries, representing approximately 93% of all savannah elephants in those countries. Elephant populations in survey areas with historical data decreased by an estimated 144,000 from 2007 to 2014, and populations are currently shrinking by 8% per year continent-wide, primarily due to poaching. Though 84% of elephants occurred in protected areas, many protected areas had carcass ratios that indicated high levels of elephant mortality. Results of the GEC show the necessity of action to end the African elephants' downward trajectory by preventing poaching and protecting habitat.

  17. Mid-J CO Shock Tracing Observations of Infrared Dark Clouds. III. SLED Fitting

    NASA Astrophysics Data System (ADS)

    Pon, A.; Kaufman, M. J.; Johnstone, D.; Caselli, P.; Fontani, F.; Butler, M. J.; Jiménez-Serra, I.; Palau, A.; Tan, J. C.

    2016-08-01

    Giant molecular clouds contain supersonic turbulence that can locally heat small fractions of gas to over 100 K. We run shock models for low-velocity, C-type shocks propagating into gas with densities between 103 and 105 cm-3 and find that CO lines are the most important cooling lines. Comparison to photodissociation region (PDR) models indicates that mid-J CO lines (J = 8 \\to 7 and higher) should be dominated by emission from shocked gas. In Papers I and II we presented CO J = 3 \\to 2, 8 \\to 7, and 9 \\to 8 observations toward four primarily quiescent clumps within infrared dark clouds. Here we fit PDR models to the combined spectral line energy distributions and show that the PDR models that best fit the low-J CO emission underpredict the mid-J CO emission by orders of magnitude, strongly hinting at a hot gas component within these clumps. The low-J CO data clearly show that the integrated intensities of both the CO J = 8 \\to 7 and 9 \\to 8 lines are anomalously high, such that the line ratio can be used to characterize the hot gas component. Shock models are reasonably consistent with the observed mid-J CO emission, with models with densities near {10}4.5 cm-3 providing the best agreement. Where this mid-J CO is detected, the mean volume filling factor of the hot gas is 0.1%. Much of the observed mid-J CO emission, however, is also associated with known protostars and may be due to protostellar feedback.

  18. Investigation of copper(II) binding to the protein precursor of Non-Amyloid-Beta Component of Alzheimer Disease Amyloid Plaque

    NASA Astrophysics Data System (ADS)

    Rose, Francis; Hodak, Miroslav; Bernholc, Jerry

    2007-03-01

    The Non-Amyloid-Beta Component Precursor (NACP) is a natively unfolded synaptic protein that is implicated in Alzheimers and Parkinsons diseases. Its aggregation into fibrillar structures is accelerated by the binding of copper(II). Experimental studies suggest that the dominant copper binding site is located at the histidine residue in NACP. Based on this evidence we assembled a model fragment of the binding site and used DFT to analyze the conformational details of the most probable binding motifs. We investigated the overall conformational effects with classical MD by constraining the copper binding site to the most energetically favorable geometry obtained from the DFT calculations. These results are compared and contrasted with those of the unbound NACP.

  19. Micro-Raman spectroscopy study of the effect of Mid-Ultraviolet radiation on erythrocyte membrane.

    PubMed

    Li, N; Li, S X; Guo, Z Y; Zhuang, Z F; Li, R; Xiong, K; Chen, S J; Liu, S H

    2012-07-02

    Mid-Ultraviolet (UVB) has a significant influence on human health. In this study, human erythrocytes were exposed to UVB to investigate the effects of UVB radiation on erythrocytes membrane. And Micro-Raman spectroscopy was employed to detect the damage. Principal component analysis (PCA) was used to classify the control erythrocytes and the irradiated erythrocytes. Results showed that the erythrocytes membrane was damaged by Mid-Ultraviolet (UVB) radiation. The intensity of the Raman peaks at 1126 cm(-1) and 1082 cm(-1) were used to calculate the Longitudinal Order-Parameters in Chains (S(trans)) which can present the liquidity and ionic permeability of erythrocyte membrane. After UVB radiation for 30 min, both the liquidity and ionic permeability decreased. At the same time, the intensity of the peaks at 1302 cm(-1) (α-helix), 1254 cm(-1) (random coil), 1452 cm(-1) and 1430 cm(-1) (CH(2)/CH(3) stretch) have also changed which indicated the membrane protein also been damaged by UVB. In the whole process of radiation, the more UVB radiation dose the more damage on the erythrocyte membrane. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. Interactions between tropical cyclones and mid-latitude systems in the Northeastern Pacific

    NASA Astrophysics Data System (ADS)

    Lugo, A.; Abarca, S. F.; Raga, G. B.; Vargas, D. C.

    2014-12-01

    Major challenges in tropical meteorology include the short-term forecast of tropical cyclone (TC) intensity, which is defined as the maximum tangential wind. Several efforts have been made in order to reach this goal over the last decade: Among these efforts, the study of lightning in the TC inner core (the region inside a disc of 100 km radius from the center) as a proxy to deep convection, has the potential to be used as a predictor to forecast intensity (DeMaria et al, 2012, Mon. Wea. Rev., 140, 1828-1842).While most studies focus their objectives in studying the lightning flash density in the inner core, we study the probability of flash occurrence for intensifying and weakening cyclones. We have analyzed the trajectories of the observed 62 tropical cyclones that developed in the basin from 2006 to 2009, and classified them into separate clusters according to their trajectories. These clusters can broadly be described as having trajectories mostly oriented: East-West, towards the central Pacific, NW far from the Mexican coast, parallel to the Mexican coast and recurving towards the Mexican coast.We estimate that probability of inner core lightning occurrence increases as cyclones intensify but the probability rapidly decrease as the systems weaken. This is valid for cyclones in most of the clusters. However, the cyclones that exhibit trajectories that recurve towards the Mexican coast, do not present the same relationship between intensity and inner-core lightning probability, these cyclones show little or no decrease in the lightning occurrence probability as they weaken.We hypothesize that one of the reasons for this anomalous behavior is likely the fact that these cyclones interact with mid-latitude systems. Mid-latitude systems are important in determining the recurving trajectory but they may also influence the TC by advecting mid-level moisture towards the TC inner core. This additional supply of moisture as the system is approaching land may enhance deep

  1. An Analysis of the Environments of Intense Convective Systems in West Africa in 2003

    NASA Technical Reports Server (NTRS)

    Nicholls, Stephen D.; Mohr, Karen I.

    2010-01-01

    We investigated the local- and regional-scale thermodynamical and dynamical environments associated with intense convective systems in West Africa during 2003. We identified convective system cases from TRMM microwave imagery, classifying each case by the system minimum 85-GHz brightness temperature and by the estimated elapsed time of propagation from high terrain. The speed of the mid-level jet, the magnitude of the low-level shear, and the surface equivalent potential temperature (theta(sub e)) were greater for the intense cases compared to the non-intense cases, although the differences between the means tended to be small, less than 3K for surface theta(sub e). Hypothesis testing of a series of commonly used intensity prediction metrics resulted in significant results only for low-level metrics such as convective available potential energy and not for any of the mid- or upper-level metrics such as 700-hPa theta(sub e). None of the environmental variables or intensity metrics by themselves or in combination appeared to be reliable direct predictors of intensity. In the regional scale analysis, the majority of intense convective systems occurred in the surface baroclinic zone where surface theta(sub e) exceeded 344 K and the 700-hPa zonal wind speeds were less than -6/ms. Fewer intense cases compared to non-intense cases were associated with African easterly wave troughs. Fewer than 25% of our cases occurred in environments with detectable Saharan dust loads, and the results for intense and non-intense cases were similar. Our results for the regional analysis were consistent with the seasonal movement of the WAM and the intertropical front, regional differences in topography, and AEW energetics.

  2. Mid-infrared tunable metamaterials

    DOEpatents

    Brener, Igal; Miao, Xiaoyu; Shaner, Eric A.; Passmore, Brandon Scott

    2017-07-11

    A mid-infrared tunable metamaterial comprises an array of resonators on a semiconductor substrate having a large dependence of dielectric function on carrier concentration and a semiconductor plasma resonance that lies below the operating range, such as indium antimonide. Voltage biasing of the substrate generates a resonance shift in the metamaterial response that is tunable over a broad operating range. The mid-infrared tunable metamaterials have the potential to become the building blocks of chip based active optical devices in mid-infrared ranges, which can be used for many applications, such as thermal imaging, remote sensing, and environmental monitoring.

  3. Mid-infrared tunable metamaterials

    DOEpatents

    Brener, Igal; Miao, Xiaoyu; Shaner, Eric A; Passmore, Brandon Scott; Jun, Young Chul

    2015-04-28

    A mid-infrared tunable metamaterial comprises an array of resonators on a semiconductor substrate having a large dependence of dielectric function on carrier concentration and a semiconductor plasma resonance that lies below the operating range, such as indium antimonide. Voltage biasing of the substrate generates a resonance shift in the metamaterial response that is tunable over a broad operating range. The mid-infrared tunable metamaterials have the potential to become the building blocks of chip based active optical devices in mid-infrared ranges, which can be used for many applications, such as thermal imaging, remote sensing, and environmental monitoring.

  4. Novel magnetic nanoparticle-containing adhesive with greater dentin bond strength and antibacterial and remineralizing capabilities.

    PubMed

    Li, Yuncong; Hu, Xiaoyi; Xia, Yang; Ji, Yadong; Ruan, Jianping; Weir, Michael D; Lin, Xiaoying; Nie, Zhihong; Gu, Ning; Masri, Radi; Chang, Xiaofeng; Xu, Hockin H K

    2018-06-20

    A nanoparticle-doped adhesive that can be controlled with magnetic forces was recently developed to deliver drugs to the pulp and improve adhesive penetration into dentin. However, it did not have bactericidal and remineralization abilities. The objectives of this study were to: (1) develop a magnetic nanoparticle-containing adhesive with dimethylaminohexadecyl methacrylate (DMAHDM), amorphous calcium phosphate nanoparticles (NACP) and magnetic nanoparticles (MNP); and (2) investigate the effects on dentin bond strength, calcium (Ca) and phosphate (P) ion release and anti-biofilm properties. MNP, DMAHDM and NACP were mixed into Scotchbond SBMP at 2%, 5% and 20% by mass, respectively. Two types of magnetic nanoparticles were used: acrylate-functionalized iron nanoparticles (AINPs); and iron oxide nanoparticles (IONPs). Each type was added into the resin at 1% by mass. Dentin bonding was performed with a magnetic force application for 3min, provided by a commercial cube-shaped magnet. Dentin shear bond strengths were measured. Streptococcus mutans biofilms were grown on resins, and metabolic activity, lactic acid and colony-forming units (CFU) were determined. Ca and P ion concentrations in, and pH of biofilm culture medium were measured. Magnetic nanoparticle-containing adhesive using magnetic force increased the dentin shear bond strength by 59% over SBMP Control (p<0.05). Adding DMAHDM and NACP did not adversely affect the dentin bond strength (p>0.05). The adhesive with MNP+DMAHDM+NACP reduced the S. mutans biofilm CFU by 4 logs. For the adhesive with NACP, the biofilm medium became a Ca and P ion reservoir. The biofilm culture medium of the magnetic nanoparticle-containing adhesive with NACP had a safe pH of 6.9, while the biofilm medium of commercial adhesive had a cariogenic pH of 4.5. Magnetic nanoparticle-containing adhesive with DMAHDM and NACP under a magnetic force yielded much greater dentin bond strength than commercial control. The novel adhesive

  5. Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s

    NASA Astrophysics Data System (ADS)

    DU, Y.; Zhang, Y.

    2016-02-01

    A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004-2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate.

  6. Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s

    NASA Astrophysics Data System (ADS)

    Du, Yan; Zhang, Yuhong; Feng, Ming; Wang, Tianyu; Zhang, Ningning; Wijffels, Susan

    2015-11-01

    A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004-2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate.

  7. Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s

    PubMed Central

    Du, Yan; Zhang, Yuhong; Feng, Ming; Wang, Tianyu; Zhang, Ningning; Wijffels, Susan

    2015-01-01

    A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004–2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate. PMID:26522168

  8. Decadal trends of the upper ocean salinity in the tropical Indo-Pacific since mid-1990s.

    PubMed

    Du, Yan; Zhang, Yuhong; Feng, Ming; Wang, Tianyu; Zhang, Ningning; Wijffels, Susan

    2015-11-02

    A contrasting trend pattern of sea surface salinity (SSS) between the western tropical Pacific (WTP) and the southeastern tropical Indian Ocean (SETIO) is observed during 2004-2013, with significant salinity increase in the WTP and freshening in the SETIO. In this study, we show that increased precipitation around the Maritime Continent (MC), decreased precipitation in the western-central tropical Pacific, and ocean advection processes contribute to the salinity trends in the region. From a longer historical record, these salinity trends started in the mid-1990s, a few years before the Global Warming Hiatus from 1998 to present. The salinity trends are associated a strengthening trend of the Walker Circulation over the tropical Indo-Pacific, which have reversed the long-term salinity changes in the tropical Indo-Pacific as a consequence of global warming. Understanding decadal variations of SSS in the tropical Indo-Pacific will better inform on how the tropical hydrological cycle will be affected by the natural variability and a warming climate.

  9. Staying the Course: Vital U.S. Interests on the African Continent

    DTIC Science & Technology

    2012-03-13

    much needed agricultural development. On the continent in which desertification has its greatest impact,11 taking action to minimize avoidable stress on... Desertification Home Page at ―Regions-Africa,‖ http://www.unccd.int (accessed March 12, 2012). 12 Gianluca Rampolla, ―Transforming Risks into Cooperation

  10. Arc-continent collision of the Coastal Range in Taiwan: Geochronological constraints from U-Pb ages of zircons

    NASA Astrophysics Data System (ADS)

    Geng, Wei; Zhang, Xun-Hua; Huang, Long

    2018-04-01

    The oblique arc-continent collision between the Luzon arc and the southeastern margin of the Eurasian continent caused the uplift of Taiwan. The Coastal Range in eastern Taiwan is the northern section of the Luzon arc in the collision zone and thus records important information about the arc-continent collision. In this paper, we determine and analyze the U-Pb ages of magmatic zircons from the volcanic arc and clastic zircons from the fore-arc basin in the Coastal Range. For the volcanic arc in the Coastal Range, the eruption ages range from 16.8-5 Ma. Given that the initial subduction of the South China Sea oceanic crust (17 Ma) occurred before the Luzon arc formed, we conclude that the volcanic activity of the Coastal Range began at 16.8 ± 1.3 Ma; it was most active from 14 to 8 Ma and continued until approximately 5 Ma. The U-Pb chronology also indicates that the initial stage of arc-continent collision of the Coastal Range started at approximately 5 Ma, when the northern section of the Luzon arc moved away from the magmatic chamber because of the kinematics of the Philippine Sea Plate.

  11. Mid-continent earthquake zones; lessons from New Madrid, Missouri

    USGS Publications Warehouse

    Mitchell, B. J.

    1991-01-01

    Many seismically active regions occur throughout the world as concentrated zones surrounded by the relatively stable crust of shields or platforms. Examples occur in central and eastern North America, northeastern Brazil, Australia, Norway, Svalbard, Greenland, and other places. Some of these zones, such as those at New Madrid, Missouri, and in the St. Lawrence Valley on the Canadian border, extend over relatively large areas and are marked by a high level of seismicity. Others, such as that near Anna Ohio, are smaller, and the level of activity is lower. Some zones are occasinoally sites for major earthquakes which, if they are in populated regions, can cause widespread destrucion and loss of life. 

  12. STRONG FIELD PHYSICS WITH MID INFRARED LASERS.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    POGORELSKY,I.V.

    2001-08-27

    Mid-infrared gas laser technology promises to become a unique tool for research in strong-field relativistic physics. The degree to which physics is relativistic is determined by a ponderomotive potential. At a given intensity, a 10 {micro}m wavelength CO{sub 2} laser reaches a 100 times higher ponderomotive potential than the 1 {micro}m wavelength solid state lasers. Thus, we can expect a proportional increase in the throughput of such processes as laser acceleration, x-ray production, etc. These arguments have been confirmed in proof-of-principle Thomson scattering and laser acceleration experiments conducted at BNL and UCLA where the first terawatt-class CO{sub 2} lasers aremore » in operation. Further more, proposals for the 100 TW, 100 fs CO{sub 2} lasers based on frequency-chirped pulse amplification have been conceived. Such lasers can produce physical effects equivalent to a hypothetical multi-petawatt solid state laser. Ultra-fast mid-infrared lasers will open new routes to the next generation electron and ion accelerators, ultra-bright monochromatic femtosecond x-ray and gamma sources, allow to attempt the study of Hawking-Unruh radiation, and explore relativistic aspects of laser-matter interactions. We review the present status and experiments with terawatt-class CO{sub 2} lasers, sub-petawatt projects, and prospective applications in strong-field science.« less

  13. Warming increases plant biomass and reduces diversity across continents, latitudes, and species migration scenarios in experimental wetland communities.

    PubMed

    Baldwin, Andrew H; Jensen, Kai; Schönfeldt, Marisa

    2014-03-01

    Atmospheric warming may influence plant productivity and diversity and induce poleward migration of species, altering communities across latitudes. Complicating the picture is that communities from different continents deviate in evolutionary histories, which may modify responses to warming and migration. We used experimental wetland plant communities grown from seed banks as model systems to determine whether effects of warming on biomass production and species richness are consistent across continents, latitudes, and migration scenarios. We collected soil samples from each of three tidal freshwater marshes in estuaries at three latitudes (north, middle, south) on the Atlantic coasts of Europe and North America. In one experiment, we exposed soil seed bank communities from each latitude and continent to ambient and elevated (+2.8 °C) temperatures in the greenhouse. In a second experiment, soil samples were mixed either within each estuary (limited migration) or among estuaries from different latitudes in each continent (complete migration). Seed bank communities of these migration scenarios were also exposed to ambient and elevated temperatures and contrasted with a no-migration treatment. In the first experiment, warming overall increased biomass (+16%) and decreased species richness (-14%) across latitudes in Europe and North America. Species richness and evenness of south-latitude communities were less affected by warming than those of middle and north latitudes. In the second experiment, warming also stimulated biomass and lowered species richness. In addition, complete migration led to increased species richness (+60% in North America, + 100% in Europe), but this higher diversity did not translate into increased biomass. Species responded idiosyncratically to warming, but Lythrum salicaria and Bidens sp. increased significantly in response to warming in both continents. These results reveal for the first time consistent impacts of warming on biomass and

  14. Multi-octave supercontinuum generation from mid-infrared filamentation in a bulk crystal

    PubMed Central

    Silva, F.; Austin, D.R.; Thai, A.; Baudisch, M.; Hemmer, M.; Faccio, D.; Couairon, A.; Biegert, J.

    2012-01-01

    In supercontinuum generation, various propagation effects combine to produce a dramatic spectral broadening of intense ultrashort optical pulses. With a host of applications, supercontinuum sources are often required to possess a range of properties such as spectral coverage from the ultraviolet across the visible and into the infrared, shot-to-shot repeatability, high spectral energy density and an absence of complicated pulse splitting. Here we present an all-in-one solution, the first supercontinuum in a bulk homogeneous material extending from 450 nm into the mid-infrared. The spectrum spans 3.3 octaves and carries high spectral energy density (2 pJ nm−1–10 nJ nm−1), and the generation process has high shot-to-shot reproducibility and preserves the carrier-to-envelope phase. Our method, based on filamentation of femtosecond mid-infrared pulses in the anomalous dispersion regime, allows for compact new supercontinuum sources. PMID:22549836

  15. Sn-wave velocity structure of the uppermost mantle beneath the Australian continent

    NASA Astrophysics Data System (ADS)

    Wei, Zhi; Kennett, Brian L. N.; Sun, Weijia

    2018-06-01

    We have extracted a data set of more than 5000 Sn traveltimes for source-station pairs within continental Australia, with 3-D source relocation using Pn arrivals to improve data consistency. We conduct tomographic inversion for S-wave-speed structure down to 100 km using the Fast Marching Tomography (FMTOMO) method for the whole Australian continent. We obtain a 3-D model with potential resolution of 3.0° × 3.0°. The new S-wave-speed model provides strong constraints on structure in a zone that was previously poorly characterized. The S velocities in the uppermost mantle are rather fast, with patterns of variation generally corresponding to those for Pn. We find strong heterogeneities of Swave speed in the uppermost mantle across the entire continent of Australia with a close relation to crustal geological features. For instance, the cratons in the western Australia usually have high S velocities (>4.70 km s-1), while the volcanic regions on the eastern margin of Australia are characterized by low S velocities (<4.40 km s-1). Exploiting an equivalent Pn inversion, we also determine the Vp/Vs ratios across the whole continent. We find that most of the uppermost mantle has Vp/Vs between 1.65 and 1.85, but with patches in central Australia and in the east with much higher Vp/Vs ratios. Distinctive local anomalies on the eastern margin may indicate the positions of remnants of mantle plumes.

  16. Clinical application of continent anal plug in bedridden patients with intractable diarrhea.

    PubMed

    Kim, J; Shim, M C; Choi, B Y; Ahn, S H; Jang, S H; Shin, H J

    2001-08-01

    Some patients bedridden from various causes such as stroke or spinal cord injury experience poor control of bowel movement. This causes fecal leakage and diarrhea, increases the risk of perianal excoriation and bed sores, and is a burden on caregivers. To evaluate the efficacy of fecal evacuation and the prevention and treatment of skin complications in intractable diarrhea patients using a new device. A continent anal plug (US Patent No. 5 569 216) comprises an inner balloon surrounded by an outer balloon, both of which are mounted on a silicone tube containing a pair of air passages and an enema fluid inlet. The tube is secured in place in the rectum by the inflatable outer balloon and is designed to drain fecal matter through a thin collapsible hose situated in the anal canal. Thirty-two patients (21 male; median age 61 (range, 28-76) years) were evaluated after fully informed consent. Median duration was 12 (range, 3-37) days. The continent anal plug evacuated efficiently in those patients with loose or watery stools who only required irrigation once daily or not at all. Skin excoriations improved in three to seven days. Minimal leakage was seen around the anus. There was no anorectal mucosal injury noted over 37 days. The continent anal plug is an efficient method of treating patients with loss of bowel control and incontinence because it enables controlled fecal evacuation and helps reduce skin complications without causing anorectal mucosal injury.

  17. Improved quality of life and sexuality with continent urinary diversion in quadriplegic women with umbilical stoma.

    PubMed

    Moreno, J G; Chancellor, M B; Karasick, S; King, S; Abdill, C K; Rivas, D A

    1995-08-01

    Quality of life issues prompted us to offer continent urinary diversion to quadriplegic women who required cystectomy for end-stage neurogenic vesical dysfunction complicated by urethral destruction as a result of chronic indwelling catheterization. Three women with spinal cord injury (SCI) and resultant quadriplegia of 5 to 15 years duration underwent continent urinary diversion. Preoperative evaluation and urodynamic studies in each showed a bladder capacity of less than 150mL, bilateral vesicoureteral reflux, recurrent febrile urinary tract infections, an incompetent urethral sphincter, and incontinence around an indwelling catheter in all three patients. Although highly motivated, these women showed minimal dexterity and were unable to perform urethral self-catheterization. Each was opposed to having an incontinent abdominal urinary stoma. The urinary reservoir was created from 30cm of detubularized right colon. The continence mechanism used an intussuscepted and imbricated ileocecal valve. The umbilicus was chosen as the urostomy site because of cosmetic appearance and ease of catheterization for a patient with minimal dexterity. Follow-up ranged from 18 to 30 months. Reservoir capacity ranged from 550 to 800mL without evidence of reflux or stomal leakage. The incidence of symptomatic autonomic dysreflexia and urinary tract infection decreased postoperatively in all patients. Of the two women who were sexually active, the frequency of activity increased from 8 to 15 episodes per month in one and 3 to 4 episodes per month in the other. Both reported improved sexual enjoyment. Body image and satisfaction with urologic management increased in all three patients. In conclusion, continent urinary diversion in selected quadriplegic patients is a reasonable alterative to incontinent intestinal urinary diversion. The umbilical stoma provides an excellent cosmetic result which patients with minimal dexterity are able to catheterize easily. Continent urinary diversion

  18. Magnitude and Spatial Distribution of Impact Intensity Under the Foot Relates to Initial Foot Contact Pattern.

    PubMed

    Breine, Bastiaan; Malcolm, Philippe; Segers, Veerle; Gerlo, Joeri; Derie, Rud; Pataky, Todd; Frederick, Edward C; De Clercq, Dirk

    2017-12-01

    In running, foot contact patterns (rear-, mid-, or forefoot contact) influence impact intensity and initial ankle and foot kinematics. The aim of the study was to compare impact intensity and its spatial distribution under the foot between different foot contact patterns. Forty-nine subjects ran at 3.2 m·s -1 over a level runway while ground reaction forces (GRF) and shoe-surface pressures were recorded and foot contact pattern was determined. A 4-zone footmask (forefoot, midfoot, medial and lateral rearfoot) assessed the spatial distribution of the vertical GRF under the foot. We calculated peak vertical instantaneous loading rate of the GRF (VILR) per foot zone as the impact intensity measure. Midfoot contact patterns were shown to have the lowest, and atypical rearfoot contact patterns the highest impact intensities, respectively. The greatest local impact intensity was mainly situated under the rear- and midfoot for the typical rearfoot contact patterns, under the midfoot for the atypical rearfoot contact patterns, and under the mid- and forefoot for the midfoot contact patterns. These findings indicate that different foot contact patterns could benefit from cushioning in different shoe zones.

  19. [Physics of materials and female stress urinary continence: New concepts: I) Elasticity under bladder].

    PubMed

    Guerquin, B

    2015-09-01

    Improving the understanding of the adaptation to stress of urinary continence. A transversal analysis between physics of materials and the female anatomy. Laws of physics of the materials and of their viscoelastic behavior are applied to the anatomy of the anterior vaginal wall. The anterior vaginal wall may be divided into two segments of different viscoelastic behavior, the vertical segment below the urethra and the horizontal segment below the bladder. If the urethra gets crushed on the first segment according to the hammock theory, the crushing of the bladder on the second segment is, on the other hand, damped by its important elasticity. The importance of this elasticity evokes an unknown function: damping under the bladder that moderates and delays the increase of intravesical pressure. This damping function below the bladder is increased in the cystocele, which is therefore a continence factor; on the other hand, it is impaired in obesity, which is therefore a factor of SUI. It is necessary to include in the theory of stress continence, the notion of a damping function below the bladder. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  20. Seismic multiple attenuation in the northern continent-ocean transition zone of the South China Sea

    NASA Astrophysics Data System (ADS)

    Chen, N.; Li, C. F.

    2017-12-01

    In seismic exploration, especially in marine oil and gas exploration, presence of multiple reflections lowers signal-to-noise ratio of seismic data and makes it difficult to analyze seismic velocity. In northern continent-ocean transition zone of the South China Sea (SCS), low-velocity Cenozoic strata cover sets of high-velocity carbonate strata directly, and over 1000 m thick of sediments were deposited on the igneous basement in the northwest SCS. These sedimentary boundaries generate quite strong impedance interfaces and strong internal multiples. Diffractions as a result of variation of seabed topography, coupled with the vibration, free surface multiples and refraction multiples, cause a variety of strong energy disturbances and missing of frequency component. In this study, we process four recently acquired multichannel reflection seismic profiles from the northern continent-ocean transition zone of the SCS with a new combination of demultiple techniques. There is a variety of strong multiples in the raw data, and the seabed multiple occurs between 9 to 11 seconds in two-way travel time (TWTT), and we apply Surface-related Multiple Elimination (SRME) to attenuate the free surface multiples. After SRME, we use high-resolution Radon transform (RAMUR) to attenuate deep multiples concentrating below 10 seconds in TWTT. Normal moveout correction (NMO) is necessary to flatten true reflections and turn multiples into a parabola before RAMUR, and we can attenuate the deep multiples in theτ-p domain. The seabed topography varies greatly in the continent-ocean transition zone, so the diffractions are well developed. However, SRME and RAMUR are not effective in attenuating diffractions and internal multiples. We select diffracted multiple attenuation (DIMAT) after many trials and detailed analysis. The diffractions are extracted in decomposed frequency bands. The internal multiples below 11 seconds in TWTT and high-amplitude noises are successfully suppressed while

  1. Image of the Moho across the continent-ocean transition, US east coast

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holbrook, W.S.; Purdy, G.M.; Reiter, E.C.

    1992-03-01

    Strong wide-angle reflections from the Moho were recorded by ocean-bottom seismic instruments during the 1988 Carolina Trough multichannel seismic experiment, in an area where the Moho is difficult to detect with vertical-incidence seismic data. Prestack depth migration of these reflections has enabled the construction of a seismic image of the Moho across the continent-ocean transition of a sedimented passive margin. The Moho rises across the margin at a slope of 10{degree}-12{degree}, from a depth of about 33 km beneath the continental shelf to 20 km beneath the outer rise. This zone of crustal thinning defines a distinct, 60-70-km-wide continent-ocean transitionmore » zone. The authors interpret the Moho in the Carolina Trough as a Jurassic feature, formed by magmatic intrusion and underplating during the rifting of Pangea.« less

  2. Monolithically Integrated Mid-Infrared Quantum Cascade Laser and Detector

    PubMed Central

    Schwarz, Benedikt; Reininger, Peter; Detz, Hermann; Zederbauer, Tobias; Andrews, Aaron Maxwell; Schrenk, Werner; Strasser, Gottfried

    2013-01-01

    We demonstrate the monolithic integration of a mid-infrared laser and detector utilizing a bi-functional quantum cascade active region. When biased, this active region provides optical gain, while it can be used as a detector at zero bias. With our novel approach we can measure the light intensity of the laser on the same chip without the need of external lenses or detectors. Based on a bound-to-continuum design, the bi-functional active region has an inherent broad electro-luminescence spectrum of 200 cm−1, which indicate sits use for single mode laser arrays. We have measured a peak signal of 191.5 mV at theon-chip detector, without any amplification. The room-temperature pulsed emission with an averaged power consumption of 4 mW and the high-speed detection makes these devices ideal for low-power sensors. The combination of the on-chip detection functionality, the broad emission spectrum and the low average power consumption indicates the potential of our bi-functional quantum cascade structures to build a mid-infrared lab-on-a-chip based on quantum cascade laser technology. PMID:23389348

  3. Mid-IR Atmospheric Tracers of Jupiter's Storm Oval BA

    NASA Astrophysics Data System (ADS)

    Shannon, Matthew J.; Orton, G.; Fletcher, L.

    2010-10-01

    The 2005-2006 reddening of a major anticyclonic storm, known as Oval BA, in Jupiter's turbulent atmosphere may well be a paradigm for the formation of red-colored vortices on the giant planets, including Jupiters Great Red Spot. Mid-infrared observations can be effectively used to determine physical and chemical properties of the atmosphere, and we present the results of mid-infrared thermal imaging observations, collected from NASAs Infrared Telescope Facility (IRTF) in Hawaii, ESOs Very Large Telescope (VLT) in Chile and the NAOJ Subaru Telescope in Hawaii between spring of 2005 and summer of 2006. These address the role of atmospheric tracers, including cloud opacity, the ammonia gas content, and the variation of the fraction of para- to ortho-hydrogen from local thermal equilibrium in assessing the rate of upwelling. These properties were retrieved with the Oxford-developed code, Nemesis, with the purpose of providing constraints on dynamical models in an effort to identify the mechanism for the color change. The most obvious change is that the temperature gradient from the inner to the outer part of Oval BA increased over the time of the color change, indicating a strengthening of the intensity of the vortex.

  4. Plasma optical modulators for intense lasers

    PubMed Central

    Yu, Lu-Le; Zhao, Yao; Qian, Lie-Jia; Chen, Min; Weng, Su-Ming; Sheng, Zheng-Ming; Jaroszynski, D. A.; Mori, W. B.; Zhang, Jie

    2016-01-01

    Optical modulators can have high modulation speed and broad bandwidth, while being compact. However, these optical modulators usually work for low-intensity light beams. Here we present an ultrafast, plasma-based optical modulator, which can directly modulate high-power lasers with intensity up to 1016 W cm−2 to produce an extremely broad spectrum with a fractional bandwidth over 100%, extending to the mid-infrared regime in the low-frequency side. This concept relies on two co-propagating laser pulses in a sub-millimetre-scale underdense plasma, where a drive laser pulse first excites an electron plasma wave in its wake while a following carrier laser pulse is modulated by the plasma wave. The laser and plasma parameters suitable for the modulator to work are based on numerical simulations. PMID:27283369

  5. The place of science in a continent at the crossroads.

    PubMed

    Koech, D K

    2001-01-01

    I have mentioned it before and I want to repeat it now, that we in Africa share a common history, heritage and basic problems of development. We, therefore, have an inescapable responsibility of pooling our talents and resources in shaping our common destiny. In fulfillment of its mission, AFHES, through its organized con notgresses and this Journal, is an invaluable vessel for enabling us to promote better health for the peoples of this continent. Africa is a continent endowed with great potential that, for one reason or an notother, has been ignored or misused, resulting in the current crisis now enveloping the continent. There is the escalating debt burden, falling agricultural productivity and the ever-increasing population. Efforts to improve the situation are hampered by adverse factors such as malnutrition, HTV/AIDS, malaria and other causes of ill health; wars, poor environmental management and the ever-worrisome problem of refugees. At the sunrise of the 21st Century, we must wake up and reverse the current trend by focusing our resources on priority areas of development. The fight for freedom from the yoke of colonialism and the traumatic experience of apartheid has been won. In some African countries, however, the winning of the fight for freedom has opened up a new fight, a fight that is more fierce and bloody than that which set us free. These include civil strife and internecine wars giving rise to a new black Diaspora, which is far greater than the one experienced during the period of slavery and slave trade. People supposed to build these nations have either been killed or forced into exile. Those intellectually endowed have sought refuge in safer and economically developed countries and, by the same process, also weaken the al notready weak economies of their mother countries. They have, therefore, helped to strengthen the already strong economies of the developed nations. This is indeed, a sad situation that poses a formidable challenge to the

  6. Did the Mid-Pliocene warmth bring the Northern Hemisphere Chill?

    NASA Astrophysics Data System (ADS)

    Rosenthal, Y.; Woodard, S. C.; Evans, D. A.; Haynes, L.; Sosdian, S. M.; Lear, C. H.; Hoenisch, B.; Erez, J.

    2015-12-01

    The relatively fast transition from the warm Pliocene to the Northern Hemisphere Glaciation (NHG) is puzzling. We have previously suggested that expansion of Antarctic glaciation following the mid-Pliocene warm period altered the oceanic circulation and inter-hemispheric transfer of heat and salt thereby providing a dynamic trigger for the intensification of the NHG at ~2.75 Ma and the ensuing glacial cycles (Woodard et al., 2014). Here we explore the hypothesis that enhanced chemical weathering under the warm Pliocene conditions contributed to the gradual cooling leading to the dynamic shift in ocean circulation. Using foraminiferal core-top and culture calibrations we have developed a new multi-elemental proxy approach for reconstructing changes in ocean calcium ([Ca]) and other major ion concentrations throughout the past ~3 Myr. Foraminiferal records from several drill sites in the Atlantic and Pacific Oceans suggest that seawater [Ca] was ~20±5% higher during the mid-Pliocene period (~2.7-3.2 Ma) than at present, and gradually reaching modern seawater concentration by the early Pleistocene. Other seawater ion concentrations (e.g., Sr, Li, B) were also significantly higher at that time than at present. Correction for the estimated change in seawater Mg/Ca yields mid-Pliocene sea surface temperatures in the western equatorial Pacific ~1-2° warmer than today. We suggest that the higher seawater major-ion concentrations, reconstructed here, reflect enhanced chemical weathering, likely due to more intense tropical hydrologic cycle at that time. The implied increase in seawater alkalinity under the mid-Pliocene warm conditions could have acted to sequester atmospheric CO2 thus providing a negative feedback that possibly contributed to global cooling. References: Woodard, S.C., Rosenthal, Y., Miller, K.G., Wright, J.V., Chiu, B.K. and K.T. Lawrence. (2014). Antarctic role in Northern Hemisphere Glaciation. Science, 346:847-850.

  7. A Study of Ionospheric Storm Association with Intense Geomagnetic Storms

    NASA Astrophysics Data System (ADS)

    Okpala, K. C.

    2017-12-01

    The bulk association between ionospheric storms and geomagnetic storms have been studied. Hemispheric features of seasonal variation of ionospheric storms in the mid-latitude were also investigated. 188 intense geomagnetic storms (Dst ≤100nT) that occurred during solar cycle 22 and 23 were considered, of which 143 were observed to be identified with an ionospheric storm. Individual ionospheric storms were identified as maximum deviations of the F2 layer peak electron density from quiet time values. Only ionospheric storms that could clearly be associated with the peak of a geomagnetic storms were considered. Data from two mid-latitude ionosonde stations; one in the northern hemisphere (i.e Moscow) and the other in the southern hemisphere (Grahamstown) were used to study ionospheric condition at the time of the individual geomagnetic storms. Results show hemispheric and latitudinal differences in the intensity and nature of ionospheric storms association with different types of geomagnetic storms. These results are significant for our present understanding of the mechanisms which drive the changes in electron density during different types of ionospheric storms.

  8. Comparative urodynamic studies of continent and stress incontinent women in pregnancy and in the puerperium.

    PubMed

    Iosif, S; Ulmsten, U

    1981-07-15

    Twelve pregnant women were examined by urethral pressure profile measurement and simultaneous urethrocystometry early in pregnancy (weeks 12 to 16), in the thirty-eighth week, and 5 to 7 days after delivery. All patients reported symptoms of stress incontinence starting at an early 5 to 7 days after delivery. All patients reported symptoms of stress incontinence starting at an early gestational age, it was found that that the stress incontinent women, compared to 14 continent, healthy women from whom measurements were obtained earlier, had shorter urethral lengths. Furthermore, no increase in urethral length during pregnancy was registered among the stress incontinent women, whereas such an increase did occur in the continent women. In contrast to the continent women, the incontinent patients had a low urethral closure pressure at rest and this pressure did not appear to increase sufficiently to compensate for the progressive increase in bladder pressure during pregnancy. As a result the urethral closure pressure in the stress incontinent women, therefore, decreased more and more during stress situations as pregnancy progressed, resulting in an increased leakage of urine.

  9. Resonant absorption induced fast melting studied with mid-IR QCLs.

    PubMed

    Lu, Jie; Lv, Yankun; Ji, Youxin; Tang, Xiaoliang; Qi, Zeming; Li, Liangbin

    2017-02-01

    We demonstrate the use of a pump-probe setup based on two mid-infrared quantum cascade lasers (QCLs) to investigate the melting and crystallization of materials through resonant absorption. A combination of pump and probe beams fulfills the two-color synchronous detection. Furthermore, narrow linewidth advances the accuracy of measurements and the character of broad tuning range of QCLs enables wide applications in various sample and multiple structures. 1-Eicosene was selected as a simple model system to verify the feasibility of this method. A pulsed QCL was tuned to the absorption peak of CH 2 bending vibration at 1467 cm -1 to resonantly heat the sample. The other QCL in continuous mode was tuned to 1643 cm -1 corresponding the C=C stretching vibration to follow the fast melting dynamics. By monitoring the transmission intensity variation of pump and probe beams during pump-probe experiments, the resonant absorption induced fast melting and re-crystallization of 1-Eicosene can be studied. Results show that the thermal effect and melting behaviors strongly depend on the pump wavelength (resonant or non-resonant) and energy, as well as the pump time. The realization and detection of melting and recrystallization can be performed in tens of milliseconds, which improves the time resolution of melting process study based on general mid-infrared spectrum by orders of magnitude. The availability of resonant heating and detections based on mid-infrared QCLs is expected to enable new applications in melting study.

  10. Seismotectonic features of the African plate: the possible dislocation of a continent

    NASA Astrophysics Data System (ADS)

    Meghraoui, Mustapha

    2014-05-01

    The African continent is made of seismically active structures with active deformation in between main substratum shields considered as stable continental interiors. Seismically active regions are primarily located along rift zones, thrust and fold mountain belts, transform faults and volcanic fields. The active tectonic structures generated large and destructive earthquakes in the past with significant damage and economic losses in Africa. Although some regions of the continent show a low-level of seismic activity, several large earthquakes (with M > 7) have occurred in the past. The presence of major active faults that generate destructive earthquakes is among the most important geological and geophysical hazards for the continent. National and International scientific projects dealing with the seismic hazards assessment are increasing in seismically active regions in Africa. The UNESCO-SIDA/IGCP (Project 601 http://eost.u-strasbg.fr/~igcp601/) support the preparation and implementation of the "Seismotectonic Map of Africa". Therefore, new seismotectonic data with the regional analysis of earthquake hazards became necessary as a basis for a mitigation of the earthquake damage. A database in historical and instrumental seismicity, active tectonics, stress tensor distribution, earthquake geology and paleoseismology, active deformation, earthquake geodesy (GPS) and gravity, crustal structure studies, magnetic and structural segmentation, volcanic fields, collision tectonics and rifting processes is prepared to constrain the geodynamic evolution of the continent. Taking into account the geological, tectonic and geophysical characteristics, we define six seismotectonic provinces that characterize the crustal deformation. With the previously identified Somalia tectonic block, the seismotectonic and geophysical framework of the continent reveal the existence of the Cameroon volcanic line, the South African tectonic block with transform faulting and Cape folding system

  11. A Zn isotope perspective on the rise of continents.

    PubMed

    Pons, M-L; Fujii, T; Rosing, M; Quitté, G; Télouk, P; Albarède, F

    2013-05-01

    Zinc isotope abundances are fairly constant in igneous rocks and shales and are left unfractionated by hydrothermal processes at pH < 5.5. For that reason, Zn isotopes in sediments can be used to trace the changing chemistry of the hydrosphere. Here, we report Zn isotope compositions in Fe oxides from banded iron formations (BIFs) and iron formations of different ages. Zinc from early Archean samples is isotopically indistinguishable from the igneous average (δ(66) Zn ~0.3‰). At 2.9-2.7 Ga, δ(66) Zn becomes isotopically light (δ(66) Zn < 0‰) and then bounces back to values >1‰ during the ~2.35 Ga Great Oxygenation Event. By 1.8 Ga, BIF δ(66) Zn has settled to the modern value of FeMn nodules and encrustations (~0.9‰). The Zn cycle is largely controlled by two different mechanisms: Zn makes strong complexes with phosphates, and phosphates in turn are strongly adsorbed by Fe hydroxides. We therefore review the evidence that the surface geochemical cycles of Zn and P are closely related. The Zn isotope record echoes Sr isotope evidence, suggesting that erosion starts with the very large continental masses appearing at ~2.7 Ga. The lack of Zn fractionation in pre-2.9 Ga BIFs is argued to reflect the paucity of permanent subaerial continental exposure and consequently the insignificant phosphate input to the oceans and the small output of biochemical sediments. We link the early decline of δ(66) Zn between 3.0 and 2.7 Ga with the low solubility of phosphate in alkaline groundwater. The development of photosynthetic activity at the surface of the newly exposed continents increased the oxygen level in the atmosphere, which in turn triggered acid drainage and stepped up P dissolution and liberation of heavy Zn into the runoff. Zinc isotopes provide a new perspective on the rise of continents, the volume of carbonates on continents, changing weathering conditions, and compositions of the ocean through time. © 2013 Blackwell Publishing Ltd.

  12. Afriflu2--second international workshop on influenza vaccination in the African continent--8 November 2012, Cape Town (South Africa).

    PubMed

    Schoub, Barry D; Gessner, Bradford D; Ampofo, William; Cohen, Adam L; Steffen, Christoph A

    2013-08-02

    The second meeting of the Afriflu conferences took place in Cape Town, South Africa, with over 60 participants from 15 countries in Africa and also outside the continent. Significant progress in surveillance has been made in better understanding the illness burden of influenza on the continent, which limited evidence suggests is greater than that in the developed world. In southern Africa HIV and TB coinfections play a major role in increasing hospitalisation and mortality, while elsewhere in Africa other cofactors still need to be determined. There is currently no indigenous vaccine production in sub-Saharan Africa and only one facility, based in South Africa, capable of filling imported bulk. Innovative vaccine strategies will need to be explored, such as maternal immunisation, and also the possibility of other influenza vaccine options, such as live attenuated influenza vaccine for young children. Sustained indigenous vaccine production is essential for the continent to have vaccine security in the event of a pandemic even though establishing local production faces considerable challenges especially ensuring adequate markets on the continent. There is an urgent need to develop effective communication messages for decision makers as well as healthcare workers addressing the importance of influenza even in the face of the major competing health burdens of the continent. Copyright © 2013 The Authors. Published by Elsevier Ltd.. All rights reserved.

  13. Impact of regional hypothermia on urinary continence and potency after robot-assisted radical prostatectomy.

    PubMed

    Finley, David S; Chang, Alexandra; Morales, Blanca; Osann, Kathryn; Skarecky, Douglas; Ahlering, Thomas

    2010-07-01

    This is the third publication that updates clinical outcomes using a novel technique to apply locoregional hypothermia to the pelvis during robot-assisted radical prostatectomy (RARP) to reduce inflammatory injury. This report updates urinary and sexual clinical outcomes with a minimum of 1 year follow-up. Regional pelvic cooling (<30 degrees C) [corrected] was achieved with a prototype endorectal cooling balloon (ECB) during the course ofRARP. All clinical data were entered prospectively into an electronic database for historic (cases 1-666) and hypothermic groups (115 pts). Urinary and sexual outcomes were obtained using self-administered validated questionnaires. Continence was defined as no pads, and potency was defined as two affirmative answers to "erections adequate for penetration" and "were the erections satisfactory." Six patients were excluded: three ECB malfunction, three previous radiation/surgery. Median time to zero pad use was 39 days vs 62 days (hypothermic vs controls, P = 0.0003). At 1 year, overall pad-free continence was 96.3% (105/109) vs controls of 86.6%, P < 0.001. Potency was evaluated in all men (40-78 years) with preoperative International Index of Erectile Function-5 scores of 22 to 25. At 3 months, potency results were unchanged between groups: 24% vs 23%. At 15 months, the potency rates were significantly better for the hypothermic group, 83% vs controls 66%, P = 0.045. No difference in oncologic outcome was noted with cooling. Using a prototype cooling balloon, hypothermic RARP significantly improved time to continence and overall continence. Hypothermia also resulted in a modest but statistically significant improvement in potency at 15 months. Once cooling parameters have been optimized, a randomized multicenter clinical trial will be needed for validation.

  14. Globalization in Urology: A Bibliographical Analysis of Cross-Continent Publication between 2002 and 2012.

    PubMed

    Mani, Jens; Juengel, Eva; Bartsch, Georg; Filmann, Natalie; Ackermann, Hanns; Nelson, Karen; Haferkamp, Axel; Engl, Tobias; Blaheta, Roman A

    2015-01-01

    Asian scientists have now increasingly begun to contribute to globalization; yet it is not clear whether publishing in the field of urology is paralleled by elevated cross-continental scientific publishing. An exemplary bibliometric analysis of urologic journals from 3 different continents was conducted between 2002 and 2012. Based on the ISI Web of Knowledge Journal Citation Reports, 2 urologic journals with similar impact factors (IFs) in 2013 were selected from Europe ('British Journal of Urology International', 'World Journal of Urology'), Asia ('International Journal of Urology', 'Asian Journal of Andrology') and North America ('Urologic Oncology-Seminars and Original Investigations', 'Urology'). The home continent of the journal, the workplace continental affiliation of the last author, article type (clinical, experimental or review) as well as the IF were documented. Most authors published their manuscripts in journals from the same continent in which they worked. However, a significant increase in cross-continental publishing was apparent from 2002 to 2012. Asians publishing in North America increased from 17% in 2002 to 35% in 2012. Europeans also increased the number of articles they published in North American journals, while publications from North American authors were shifted towards both European and Asian journals. Experimental and clinical articles showed significant increases in cross-continental publishing, while review publishing showed no significant change. The average IF for authors from all 3 continents increased from 2002 to 2012 (p < 0.001). The largest increase in the IF was found for Asian authors (0.11 per year). Cross-continental publication significantly increased during the period from 2002 to 2012. The impact that the Asian authors have experienced was found to be gradually impacting the North American and European colleagues. © 2015 S. Karger AG, Basel.

  15. On the determination of the carbon balance of continents (Vladimir Ivanovich Vernadsky Medal Lecture)

    NASA Astrophysics Data System (ADS)

    Dolman, Albertus J. Han

    2013-04-01

    The carbon balance of regions, the size of continents, can be determined, albeit with significant uncertainty, by combining several bottom up and top down methods. The bottom up methods use eddy covariance techniques, biometric inventory measurements and modeling, while the top down methods use atmospheric observations and inverse models. There has been considerable progress in the last few years in determining these balances through more or less standard protocols, as highlighted for instance by studies of the REgional Carbon Cycle Assessment and Processes (RECAPP) project of the Global Carbon Project. Important areas where uncertainty creeps in are the scaling of point measurements in the bottom up methods, the sparseness of the observation network and the role of model and other errors in the inversion methods. Typically these balances hold for periods of several years. They therefore do not resolve the impact of anomalies in weather and climate directly. The role of management in these balances also differs for different continents. For instance in Europe management plays a strong role in the carbon balance, whereas for the Russian continent this is less important. Management in the European carbon balance may potentially override climatically driven variability. In contrast, for Russia, the importance of the role of forest is paramount, but there the vulnerability of the Arctic regions and permafrost is a key uncertainty for future behaviour. I hope to show the importance of these different aspects of the terrestrial carbon balance by comparing the two continents, and also discuss the significant uncertainty we still face in determining the carbon budgets of large areas. I will argue that we need to get a clearer picture of the role of management in these budgets, but also of the time variability of the budgets to be able to determine the impact of anomalous weather and the vulnerability in a future climate.

  16. Spatial distribution of vaginal closure pressures of continent and stress urinary incontinent women.

    PubMed

    Peng, Qiyu; Jones, Ruth; Shishido, Keiichi; Omata, Sadao; Constantinou, Christos E

    2007-11-01

    Clinically the strength of the contraction of the female pelvic floor is qualitatively evaluated by vaginal tactile palpation. We therefore developed a probe to enable the quantitative evaluation of the closure pressures along the vagina. Four force sensors mounted on the four orthogonal directions of an intra-vaginal probe were used to measure the vaginal pressure profile (VPP) along the vaginal wall. Clinical experiments on 23 controls and 10 patients with stress urinary incontinence (SUI) were performed using the probe to test the hypothesis that the strength of pelvic floor muscle (PFM) contractions, imposed by voluntary contraction, is related to urinary continence. The results show that VPPs, characterized in terms of pressure distribution on the anterior and posterior vaginal walls, are significantly greater than those in the left and right vaginal walls. When the PFM contracted, the positions of the maximum posterior pressures in continent females and SUI patients were 0.63+/-0.15 cm and 1.19+/-0.2 cm proximal from their peak points of anterior pressure, which are 1.52+/-0.09 cm and 1.69+/-0.13 cm proximal from the introitus of vagina, respectively. The statistical analysis shows that the maximum posterior vaginal pressures of the controls were significantly greater than those of the SUI patients both at rest (continent: 3.4+/-0.3 N cm(-2), SUI: 2.01+/-0.36 N cm(-2), p<0.05) and during PFM contraction (continent: 4.18+/-0.26 N cm(-2), SUI: 2.25+/-0.41 N cm(-2), p<0.01). In addition, the difference between the posterior and anterior vaginal walls is significantly increased when the controls contract the PFM. By contrast, there are no significant differences in the SUI group. The results show that the VPP measured by the prototype probe can be used to quantitatively evaluate the strength of the PFM, which is a clinical index for the diagnosis or assessment of female SUI.

  17. Investigation of conditions for the generation and propagation of low-frequency disturbances in the troposphere

    NASA Astrophysics Data System (ADS)

    Mordvinov, V. I.; Devyatova, E. V.; Kochetkova, O. S.; Oznobikhina, O. A.

    2013-01-01

    Low-frequency disturbances responsible for the excitation of torsional oscillations—variations in the zonal mean flow intensity with a characteristic scale of 15-20 days—propagating along the meridian at mid and low latitudes of both hemispheres are investigated [1]. As data observed over the eastern parts of continents and the western parts of oceans are processed with the lag correlation statistics, traveling waves intersecting the eastern parts of continents from northwest to southeast and then returning to the north along the ocean coasts are identified. In this case, trains of anomalies oriented in the zonal direction periodically appear and are destructed in the western parts of continents. The simulation of the propagation of disturbances in the quasi-geostrophic approximation made it possible to explain the specific features of lag correlation statistics over continents by the dispersion of two-dimensional Rossby waves from traveling sources. The turnover of disturbances over Asia and wave trains to the west from the pole were reproduced. Torsional oscillations caused by the dispersion of two-dimensional Rossby waves have a characteristic form of inclined bands in the latitude-time diagram, whose steepness is controlled by the velocity of displacement of the vorticity source along the meridian.

  18. Estimating the Response of Mid-latitude Orographic Precipitation to Global Warming

    NASA Astrophysics Data System (ADS)

    Shi, Xiaoming

    The possible change in orographic precipitation in response to global warming is a rising concern under climate change, which could potentially cause significant societal impact. A general circulation model was employed to simulate the climate on an aquaplanet which has idealized mountains at its mid-latitudes. It was found that orographic precipitation at northern mid-latitudes could increase by rates faster than the Clausius-Clapeyron scaling, ˜7%/K of surface warming, in doubling CO2 simulations, while at southern mid-latitudes orographic precipitation decreased. The frequency of extreme events increased at all latitudes of the idealized mountains. Through a simple diagnostic model it was revealed that the changes in the climatological means of orographic precipitation rates were mostly determined by the changes in three variables: the speed of the wind component perpendicular to a mountain, the vertical displacement of saturated parcels, and the moist adiabatic lapse rate of saturation specific humidity. The last variable had relatively uniform contribution to the total changes in orographic precipitation across different latitudes, about 4 -- 5%/K. But contributions from the changes in wind speed and saturated vertical displacement were found to have strong north-south asymmetry, which were linked to the poleward shift of storm tracks. The changes in wind speed had positive contributions in general, with larger contributions at higher mid-latitudes. While the changes in saturated vertical displacement had negative contributions at all latitudes, but larger negative contributions were located at lower mid-latitudes. Although the poleward shift of storm tracks greatly affects regional precipitation, following the poleward shift of storm tracks the cumulative distribution function (CDF) of precipitation at the latitudes of maximum precipitation in the control simulation is very similar to that in the warm climate simulation, except that precipitation intensity

  19. Nonlinear interaction of an intense radio wave with ionospheric D/E layer plasma

    NASA Astrophysics Data System (ADS)

    Sodha, Mahendra Singh; Agarwal, Sujeet Kumar

    2018-05-01

    This paper considers the nonlinear interaction of an intense electromagnetic wave with the D/E layer plasma in the ionosphere. A simultaneous solution of the electromagnetic wave equation and the equations describing the kinetics of D/E layer plasma is obtained; the phenomenon of ohmic heating of electrons by the electric field of the wave causes enhanced collision frequency and ionization of neutral species. Electron temperature dependent recombination of electrons with ions, electron attachment to O 2 molecules, and detachment of electrons from O2 - ions has also been taken into account. The dependence of the plasma parameters on the square of the electric vector of the wave E0 2 has been evaluated for three ionospheric heights (viz., 90, 100, and 110 km) corresponding to the mid-latitude mid-day ionosphere and discussed; these results are used to investigate the horizontal propagation of an intense radio wave at these heights.

  20. The danger of imperfect regulation: OxyContin use in the United States and Canada.

    PubMed

    Lexchin, Joel; Kohler, Jillian Clare

    2011-01-01

    Drug companies aggressively market their products to increase sales and economic rewards. Different countries have different regulatory regimes for controlling promotion. In the United States control rests directly with the Food and Drug Administration whereas Canada relies on a mixture of voluntary self-regulation and an autonomous agency. Each method has significant weaknesses. We examine these weaknesses by analyzing the promotion of OxyContin (the time release version of the opioid oxycodone) by Purdue in Canada and the United States. We then look at the association between promotion and the misuse and abuse of OxyContin in both countries. Finally, we advance specific recommendations for regulating promotion for drugs that may have a high abuse potential.

  1. The Feedback Between Continents and Compositional Anomalies in the Deep Mantle

    NASA Astrophysics Data System (ADS)

    Lowman, J. P.; Trim, S. J.

    2014-12-01

    Findings from global seismic tomography studies suggest that the deep mantle may harbor a pair of broad, steep-sided, relatively dense compositionally anomalous provinces. The longevity and stability of these Large Low Shear-Wave Velocity Provinces (LLSVPs) has received considerable interest but their possible influence on surface motion has drawn lesser attention. Recent work using numerical mantle convection models investigated the feedback between oceanic plate motion and high density compositional anomalies. It was found that surface mobility is affected by the presence of compositional anomalies such that critical density contrasts and volumes of the enriched material produce a transition to stagnant-lid convection. For lesser volumes and density contrast (for example, volumes that are representative of the concentrations in the Earth's mantle) the presence of the compositional anomalies affects mean plate velocity and size when compared to the characteristics of systems in which the enriched material is absent. In addition, numerous studies and lines of evidence in the geologic record suggest that the presence of the density anomalies plays a role in determining the location of mantle upwellings, which in turn influence surface dynamics. In this study, we present the results from a study implementing a two-dimensional mantle convection model featuring an anomalously dense component and distinct continental and oceanic lithosphere. The mass, momentum, and energy conservation equations are solved using a hybrid spectral-finite difference code. Compositional variations are tracked using Lagrangian tracer particles. Mobile tectonic plates are modeled using a force-balance method and plate boundary locations evolve in response to interior stresses, plate velocity, age and lithospheric chemistry (i.e., oceanic versus continental). We examine the influence of continents on compositional anomaly morphology and longevity and the influence of compositional anomalies on

  2. 40 CFR Table 3 to Subpart Uuu of... - Continous Monitoring Systems for Metal HAP Emissions From Catalytic Cracking Units

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 13 2013-07-01 2012-07-01 true Continous Monitoring Systems for Metal HAP Emissions From Catalytic Cracking Units 3 Table 3 to Subpart UUU of Part 63 Protection of... Sulfur Recovery Units Pt. 63, Subpt. UUU, Table 3 Table 3 to Subpart UUU of Part 63—Continous Monitoring...

  3. 40 CFR Table 3 to Subpart Uuu of... - Continous Monitoring Systems for Metal HAP Emissions From Catalytic Cracking Units

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 13 2012-07-01 2012-07-01 false Continous Monitoring Systems for Metal HAP Emissions From Catalytic Cracking Units 3 Table 3 to Subpart UUU of Part 63 Protection of... Sulfur Recovery Units Pt. 63, Subpt. UUU, Table 3 Table 3 to Subpart UUU of Part 63—Continous Monitoring...

  4. 40 CFR Table 3 to Subpart Uuu of... - Continous Monitoring Systems for Metal HAP Emissions From Catalytic Cracking Units

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 13 2014-07-01 2014-07-01 false Continous Monitoring Systems for Metal HAP Emissions From Catalytic Cracking Units 3 Table 3 to Subpart UUU of Part 63 Protection of... Sulfur Recovery Units Pt. 63, Subpt. UUU, Table 3 Table 3 to Subpart UUU of Part 63—Continous Monitoring...

  5. Significance of preoperatively observed detrusor overactivity as a predictor of continence status early after robot-assisted radical prostatectomy

    PubMed Central

    Yanagiuchi, Akihiro; Miyake, Hideaki; Tanaka, Kazushi; Fujisawa, Masato

    2014-01-01

    Several recent studies have reported the involvement of bladder dysfunction in the delayed recovery of urinary continence following radical prostatectomy (RP). The objective of this study was to investigate the significance of detrusor overactivity (DO) as a predictor of the early continence status following robot-assisted RP (RARP). This study included 84 consecutive patients with prostate cancer undergoing RARP. Urodynamic studies, including filling cystometry, pressure flow study, electromyogram of the external urethral sphincter and urethral pressure profile, were performed in these patients before surgery. Urinary continence was defined as the use of either no or one pad per day as a precaution only. DO was preoperatively observed in 30 patients (35.7%), and 55 (65.5%) and 34 (40.5%) were judged to be incontinent 1 and 3 months after RARP, respectively. At both 1 and 3 months after RARP, the incidences of incontinence in patients with DO were significantly higher than in those without DO. Of several demographic and urodynamic parameters, univariate analyses identified DO and maximal urethral closure pressure (MUCP) as significant predictors of the continence status at both 1 and 3 months after RARP. Furthermore, DO and MUCP appeared to be independently associated with the continence at both 1 and 3 months after RARP on multivariate analysis. These findings suggest that preoperatively observed DO could be a significant predictor of urinary incontinence early after RARP; therefore, it is recommended to perform urodynamic studies for patients who are scheduled to undergo RARP in order to comprehensively evaluate their preoperative vesicourethral functions. PMID:25038181

  6. Experiences of surgical continence management approaches for cloacal anomalies: a qualitative analysis based on 6 women.

    PubMed

    Liao, L-M; Baker, E; Boyle, M E; Woodhouse, C R J; Creighton, S M

    2014-10-01

    The aim of this qualitative study was to gain insight into health care experiences of young women diagnosed with cloacal anomalies, with a special focus on continence management. Qualitative analysis of one-to-one interviews. A tertiary center for congenital anomalies of the urogenital tract in London. Six women aged 16 to 24 with cloacal anomalies. Tape-recorded one-to-one semi-stuctured interviews with a skilled interviewer. The taped interviews were transcribed and analyzed verbatim using interpretative phenomenological analysis according to the research question. Organizing themes across all of the accounts were identified. Two organizing themes concerning our research interests are summarized. The first theme Personal Agency in the Hands of Experts focuses on the interviewees' appreciation of their life-saving surgical care and their involvement in treatment decisions. The second theme Compromises and Trade-Offs focuses on what it was like to live with the more traditional versus the more advanced continence methods. Reliability emerged as a key priority in terms of continence treatment outcome. Gratitude may have interfered with the women's honest communications during treatment decision and evaluation consultations. A more developed approach to communication about the complex interventions proposed, founded on a nuanced understanding of users perspectives, can enhance informed decision making about continence management approaches. Despite these specific gaps, the interviewees were appreciative of their care and optimistic about life. Copyright © 2014 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  7. International Continence Society guidelines on urodynamic equipment performance.

    PubMed

    Gammie, Andrew; Clarkson, Becky; Constantinou, Chris; Damaser, Margot; Drinnan, Michael; Geleijnse, Geert; Griffiths, Derek; Rosier, Peter; Schäfer, Werner; Van Mastrigt, Ron

    2014-04-01

    These guidelines provide benchmarks for the performance of urodynamic equipment, and have been developed by the International Continence Society to assist purchasing decisions, design requirements, and performance checks. The guidelines suggest ranges of specification for uroflowmetry, volume, pressure, and EMG measurement, along with recommendations for user interfaces and performance tests. Factors affecting measurement relating to the different technologies used are also described. Summary tables of essential and desirable features are included for ease of reference. It is emphasized that these guidelines can only contribute to good urodynamics if equipment is used properly, in accordance with good practice. © 2014 Wiley Periodicals, Inc.

  8. PEPFAR/DOD/Pharmaccess/Tanzania Peoples Defence Forces HIV/AIDS Program

    DTIC Science & Technology

    2009-09-01

    NACP National AIDS Control Program NGO Non Governmental Organization NLTP National Leprosy and TB Program NS National Service OIS...have an ongoing DOT-TB program monitored by the Regional Medical Officer, in line with the guidelines of the National Tuberculosis and Leprosy ...and treatment, according to the guidelines of the NACP TB Unit and the National TB and Leprosy Programme (NTLP). 48 48 C Train medical officers

  9. Seismic scatterers in the mid-lower mantle beneath Tonga-Fiji

    NASA Astrophysics Data System (ADS)

    Kaneshima, Satoshi

    2018-01-01

    We analyze deep and intermediate-depth earthquakes at the Tonga-Fiji region in order to reveal the distribution of scattering objects in the mid-lower mantle. By array processing waveform data recorded at regional seismograph stations in the US, Alaska, and Japan, we investigate S-to-P scattering waves in the P coda, which arise from kilometer-scale chemically distinct objects in the mid-lower mantle beneath Tonga-Fiji. With ten scatterers previously reported by the author included, twenty-three mid-lower mantle scatterers have been detected below 900 km depth, while scatterers deeper than 1900 km have not been identified. Strong mid-lower mantle S-to-P scattering most frequently occurs at the scatterers located within a depth range between 1400 km and 1600 km. The number of scatterers decreases below 1600 km depth, and the deeper objects tend to be weaker. The scatterer distribution may reflect diminishing elastic anomalies of basaltic rocks with depth relative to the surrounding mantle rocks, which mineral physics has predicted to occur. The predominant occurrence of strong S-to-P scattering waves within a narrow depth range may reflect significant reduction of rigidity due to the ferro-elastic transformation of stishovite in basaltic rocks. Very large signals associated with mid-mantle scatterers are observed only for a small portion of the entire earthquake-array pairs. Such infrequent observations of large scattering signals, combined with quite large event-to-event differences in the scattering intensity for each scatterer, suggest both that the strong arrivals approximately represent ray theoretical S-to-P converted waves at objects with a plane geometry. The plane portions of the strong scatterers may often dip steeply, with the size exceeding 100 km. For a few strong scatterers, the range of receivers showing clear scattered waves varies substantially from earthquake-array pair to pair. Some of the scatterers are also observed at different arrays that have

  10. The risk of urinary retention following robot-assisted radical prostatectomy and its impact on early continence outcomes.

    PubMed

    Alnazari, Mansour; Zanaty, Marc; Ajib, Khaled; El-Hakim, Assaad; Zorn, Kevin C

    2017-12-22

    We aimed to evaluate the risk factors of acute urinary retention (AUR) following robot-assisted radical prostatectomy (RARP), as well as the relationship of AUR with early continence outcomes. The records of 740 consecutive patients who underwent RARP by two experienced surgeons at our institution were retrospectively reviewed from a prospectively collected database. Multiple factors, including age, body mass index (BMI), international prostate symptom score (IPSS), prostate volume, presence of median lobe, nerve preservation status, anastomosis time, and catheter removal time (Day 4 vs. 7), were evaluated as risk factors for AUR using univariate and multivariate analysis. The relation between AUR and early return of continence (one and three months) post-RARP was also evaluated. The incidence of clinically significant vesico-urethral anastomotic (VUA) leak and AUR following catheter removal were 0.9% and 2.2% (17/740), respectively. In men who developed AUR, there was no significant relationship with regards to age, BMI, IPSS, prostatic volume, median lobe, nerve preservation, or anastomosis time; however, the incidence of AUR was significantly higher for men with catheter removal at Day 4 (4.5% [16/351]) vs. Day 7 (0.2% [1/389]) (p=0.004). Moreover, patients with early removal of the catheter (Day 4) who developed AUR had an earlier one-month return of 0-pad continence 87.5% (14/16) compared to patients without AUR 45.6% (153/335), with no significant difference at three months. While AUR is an uncommon complication of RARP, its incidence is much higher than VUA leakage. Further, it is often not well-discussed during patient counselling preoperatively. Moreover, earlier return of urinary continence was observed in patients experiencing AUR following RARP exclusively with catheter removal at Day 4. Future studies are warranted to validate the long-term impact of AUR on continence outcomes.

  11. Novel dental adhesive with triple benefits of calcium phosphate recharge, protein-repellent and antibacterial functions.

    PubMed

    Xie, Xianju; Wang, Lin; Xing, Dan; Zhang, Ke; Weir, Michael D; Liu, Huaibing; Bai, Yuxing; Xu, Hockin H K

    2017-05-01

    A new adhesive containing nanoparticles of amorphous calcium phosphate (NACP) with calcium (Ca) and phosphate (P) ion rechargeability was recently developed; however, it was not antibacterial. The objectives of this study were to: (1) develop a novel adhesive with triple benefits of Ca and P ion recharge, protein-repellent and antibacterial functions via dimethylaminohexadecyl methacrylate (DMAHDM) and 2-methacryloyloxyethyl phosphorylcholine (MPC); and (2) investigate dentin bond strength, protein adsorption, Ca and P ion concentration, microcosm biofilm response and pH properties. MPC, DMAHDM and NACP were mixed into a resin consisting of ethoxylated bisphenol A dimethacrylate (EBPADMA), pyromellitic glycerol dimethacrylate (PMGDM), 2-hydroxyethyl methacrylate (HEMA) and bisphenol A glycidyl dimethacrylate (BisGMA). Protein adsorption was measured using a micro bicinchoninic acid method. A human saliva microcosm biofilm model was tested on resins. Colony-forming units (CFU), live/dead assay, metabolic activity, Ca and P ion concentration and biofilm culture medium pH were determined. The adhesive with 5% MPC+5% DMAHDM+30% NACP inhibited biofilm growth, reducing biofilm CFU by 4 log, compared to control (p<0.05). Dentin shear bond strengths were similar (p>0.1). Biofilm medium became a Ca and P ion reservoir having ion concentration increasing with NACP filler level. The adhesive with 5% MPC+5% DMAHDM+30% NACP maintained a safe pH>6, while commercial adhesive had a cariogenic pH of 4. The new adhesive with triple benefits of Ca and P ion recharge, protein-repellent and antibacterial functions substantially reduced biofilm growth, reducing biofilm CFU by 4 orders of magnitude, and yielding a much higher pH than commercial adhesive. This novel adhesive is promising to protect tooth structures from biofilm acids. The method of using NACP, MPC and DMAHDM is promising for application to other dental materials to combat caries. Copyright © 2017 The Academy of Dental

  12. Evolution of Plate Tectonics on Earth since the Mid-Mesoarchean was Controlled by Sedimentary Fluxes from Continents to Oceans and Mantle Temperature

    NASA Astrophysics Data System (ADS)

    Sobolev, S. V.; Brown, M.

    2017-12-01

    Plate tectonics (PT) is the most important geological process operating on Earth, making it unique among the rocky planets in the Solar System. The question of how PT was initiated and which factors controlled its evolution over Earth's history are widely discussed, but remain controversial. It is broadly accepted that a necessary condition for initiation and stable operation of PT is maintaining low strength along plate boundaries, particularly along the subduction zone interfaces in the subduction channels. Examples from the South American Andes and other convergent margins show that unconsolidated continental sediments in trenches serve as an efficient lubricant for subduction; if these are lacking, friction in the subduction channel and strength of the plate boundary are significantly increased. We suggest that lubrication of subduction by accumulation of continental sediments in trenches played a crucial role during the evolution of PT on Earth since the mid-Mesoarchean. We posit that continental emergence and enhanced surface erosion caused an increasing flux of sediments into the oceans, which in turn lubricated subduction channels and intensified PT. Thus, peaks in orogenesis, as confirmed by several proxies, during periods of supercraton/supercontinent assembly represent periods of vigorous subduction and continental sedimentation in trenches prior to terminal collision. Conversely, a decrease in plate boundary length and a reduction in continental sediment accumulation in trenches during periods of stability after supercraton/supercontinent assembly is the likely reason for periods of lower PT vigor, including the so called `boring billion' between 1.8 and 0.8 Ga. The largest surface erosion and subduction-lubrication event occurred at the end of the `snowball' Earth epoch in the Neoproterozoic and likely accelerated the most recent episode of vigorous PT. Based on analysis of various geological observations, we suggest that the cyclic behavior of PT on

  13. Changes in duration and intensity of the wet spells of different intensity over Northern Eurasia and North America

    NASA Astrophysics Data System (ADS)

    Groisman, P. Y.; Gulev, S. K.; Zolina, O. G.; Wang, X. L.; Bulygina, O. N.; Knight, R. W.

    2012-04-01

    (1) According to the 20th Century Reanalysis data, there is a general century-long increase in an intensity and frequency of extratropical cyclones over the northern extratropics and an increase in their average duration, i.e., lengthening of the mean lifespan of storms. These conclusions however, have notable regional and seasonal differences (i.e., there are regions and seasons where opposite statements are true). Furthermore, all these conclusions are trustworthy only for the regions with reliable long-term synoptic information (large Europe, Northern Atlantic, the central parts of the North American continent and Northern Eurasia (Wang et al. 2012, manuscript in preparation). (2) There are indications that in the post World War II period over Europe the frequency and duration of the wet spells have changed and the occurrence of the prolonged wet spells have increased (Zolina et al. 2010). (3) At the same period over most of North America and Northern Eurasia, an increase of intense precipitation including the multi-day events was documented (Groisman et al. 2005, 2012; USCCSP 2009). Having the above as a rationale for further research, we (a) expanded the initial wet spells study into the northern extratropics and (b) estimated the frequency and duration of the wet spells of different intensity (e.g., by looking for the wet spells constructed from the days with intense precipitation only). The results of temporal changes (time series and trends) and distribution (mean values and the upper percentiles) of frequency, duration, and intensity of these wet spells will be presented at the Session for the regions of North America, Europe, and Northern Asia that are well covered by the dense networks of long-term daily and sub-daily precipitation observations.

  14. Robotic radical prostatectomy for elderly patients: probability of achieving continence and potency 1 year after surgery.

    PubMed

    Shikanov, Sergey; Desai, Vikas; Razmaria, Aria; Zagaja, Gregory P; Shalhav, Arieh L

    2010-05-01

    We assessed the probability of achieving continence and potency after robotic radical prostatectomy in elderly patients. The cohort included 1,436 robotic radical prostatectomy cases performed at our institution between 2003 and 2008. Continence (pad-free) and potency (erection sufficient for intercourse) at baseline and 1 year after surgery were evaluated by the UCLA-PCI questionnaire. Point estimates of the predicted probabilities of continence and potency for age 65, 70 and 75 years were calculated from multivariate logistic regression models adjusting for age, nerve sparing status, baseline International Prostate Symptom Score and baseline Sexual Health Inventory for Men score. Patients who were impotent before surgery or those who received hormones or radiation within 1 year after surgery were censored. Mean patient age was 60 years (range 38 to 85) with 25% older than 65 years and 77 (5%) 70 years old or older. Age (OR 0.97, p = 0.002), baseline I-PSS (OR 0.98, p = 0.02) and Sexual Health Inventory for Men scores (OR 1.02, p = 0.005) were independently associated with being pad-free. Age (OR 0.92, p <0.0001), baseline Sexual Health Inventory for Men score (OR 1.1, p <0.0001) and bilateral nerve sparing (OR 2.92, p <0.0001) were independently associated with achieving potency. Predicted probabilities (95% CI) of postoperative 1-year continence at age 65, 70 and 75 years were 0.66 (0.63, 0.69), 0.63 (0.57, 0.68) and 0.59 (0.52, 0.66), respectively. The corresponding probabilities of postoperative 1-year potency after bilateral nerve sparing were 0.66 (0.62, 0.71), 0.56 (0.49, 0.64) and 0.46 (0.36, 0.56). In our experience there is an acceptable probability of achieving continence and potency after robotic radical prostatectomy in selected elderly patients. 2010 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

  15. Calibrated Mid-wave Infrared (IR) (MidIR) and Long-wave IR (LWIR) Stokes and Degree-of-Liner Polarization (DOLP)

    DTIC Science & Technology

    2008-09-01

    LWIR long-wave IR MCT mercury cadmium telluride MidIR mid-wave IR NUC nonuniformity corrections ROI regions-of-interest 22 No. of Copies...Calibrated Mid-wave Infrared (IR) (MidIR) and Long-wave IR ( LWIR ) Stokes and Degree-of-Liner Polarization (DOLP) by Kristan P. Gurton and... LWIR ) Stokes and Degree-of-Liner Polarization (DOLP) Kristan P. Gurton and Melvin Felton Computational and Information Sciences Directorate

  16. Impact of dose intensified salvage radiation therapy on urinary continence recovery after radical prostatectomy: Results of the randomized trial SAKK 09/10.

    PubMed

    Ghadjar, Pirus; Hayoz, Stefanie; Bernhard, Jürg; Zwahlen, Daniel R; Stein, Jürgen; Hölscher, Tobias; Gut, Philipp; Polat, Bülent; Hildebrandt, Guido; Müller, Arndt-Christian; Putora, Paul Martin; Papachristofilou, Alexandros; Schär, Corinne; Dal Pra, Alan; Biaggi Rudolf, Christine; Wust, Peter; Aebersold, Daniel M; Thalmann, George N

    2018-02-01

    Adjuvant radiation therapy (aRT) after radical prostatectomy (RP) is associated with impaired urinary continence recovery as compared to surveillance. Less is known regarding the effect of salvage radiation therapy (sRT) dose intensification on continence outcomes. Urinary continence recovery was investigated within a multicentre randomized trial in biochemically recurrent prostate cancer patients who received either 64 Gy (32 fractions) or 70 Gy (35 fractions) sRT. Incontinence was assessed using Common Toxicity Criteria for Adverse Events v4.0 at baseline, at the end of sRT and 3 months afterward. Quality of life (QoL) was assessed with the EORTC QoL questionnaires C30 and PR25 at baseline and 3 months after completion of sRT. A total of 344 patients were evaluable. At baseline 233 (68%) of patients were fully continent and 14% in both arms became incontinent three months after treatment. Of the remaining 111 (32%) patients being incontinent at baseline, continence recovery was achieved 3 months after sRT by 44% vs. 41% with 64 vs. 70 Gy, respectively (p = 0.8). This analysis is limited by its short follow-up. Dose intensification of sRT had no impact on early urinary continence recovery or prevalence of de novo incontinence. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. Striking Seasonality in the Secular Warming of the Northern Continents: Structure and Mechanisms

    NASA Astrophysics Data System (ADS)

    Nigam, S.; Thomas, N. P.

    2017-12-01

    The linear trend in twentieth-century surface air temperature (SAT)—a key secular warming signal— exhibits striking seasonal variations over Northern Hemisphere continents; SAT trends are pronounced in winter and spring but notably weaker in summer and fall. The SAT trends in historical twentieth-century climate simulations informing the Intergovernmental Panel for Climate Change's Fifth Assessment show varied (and often unrealistic) strength and structure, and markedly weaker seasonal variation. The large intra-ensemble spread of winter SAT trends in some historical simulations was surprising, especially in the context of century-long linear trends, with implications for the detection of the secular warming signal. The striking seasonality of observed secular warming over northern continents warrants an explanation and the representation of related processes in climate models. Here, the seasonality of SAT trends over North America is shown to result from land surface-hydroclimate interactions and, to an extent, also from the secular change in low-level atmospheric circulation and related thermal advection. It is argued that the winter dormancy and summer vigor of the hydrologic cycle over middle- to high-latitude continents permit different responses to the additional incident radiative energy from increasing greenhouse gas concentrations. The seasonal cycle of climate, despite its monotony, provides an expanded phase space for the exposition of the dynamical and thermodynamical processes generating secular warming, and an exceptional cost-effective opportunity for benchmarking climate projection models.

  18. ECOLOGICAL CONDITION OF THE U.S. MID-ATLANTIC ESTUARIES: THE MID-ATLANTIC INTEGRATED ASSESSMENT (MAIA)

    EPA Science Inventory

    The Mid-Atlantic Integrated Assessment (MAIA-Estuaries) evaluated ecological conditions in US Mid-Atlantic estuaries during the summers of 1997 and 1998. Over 800 probability-based stations were monitored in four main estuarine systems?Chesapeake Bay, the Delaware Estuary, Maryla...

  19. Relationship of multispectral satellite data to land surface evaporation from the Australian continent

    NASA Technical Reports Server (NTRS)

    Smith, R. C. G.; Choudhury, B. J.

    1990-01-01

    Based on NOAA-9 AVHRR and Nimbus-7 SMMR satellite data, satellite indices of vegetation from the Australian continent are calculated for the period of May 1986 to April 1987. Visible (VIS) and near infrared (NIR) reflectances and the normalized difference (ND) vegetation index are calculated from the AVHRR sensor. The microwave polarization difference (PD) is also calculated as the difference between the vertically and horizontally polarized brightness temperatures at 37 GHz. ND, PD, VIS, and NIR indices were plotted against rainfall and water balance estimates of evaporation. It is concluded that direct satellite monitoring of annual evaporation across the Australian continent using PD or VIS satellite indices of vegetation biomass appears possible for areas with evaporation less than 600 mm/y and that use of the ND relationship at continental scale may underpredict monthly evaporation of forests relative to agriculture.

  20. Maritime continent coastlines controlling Earth's climate

    NASA Astrophysics Data System (ADS)

    Yamanaka, Manabu D.; Ogino, Shin-Ya; Wu, Pei-Ming; Jun-Ichi, Hamada; Mori, Shuichi; Matsumoto, Jun; Syamsudin, Fadli

    2018-12-01

    During the Monsoon Asian Hydro-Atmosphere Scientific Research and Prediction Initiative (MAHASRI; 2006-16), we carried out two projects over the Indonesian maritime continent (IMC), constructing the Hydrometeorological Array for Intraseasonal Variation-Monsoon Automonitoring (HARIMAU; 2005-10) radar network and setting up a prototype institute for climate studies, the Maritime Continent Center of Excellence (MCCOE; 2009-14). Here, we review the climatological features of the world's largest "regional" rainfall over the IMC studied in these projects. The fundamental mode of atmospheric variability over the IMC is the diurnal cycle generated along coastlines by land-sea temperature contrast: afternoon land becomes hotter than sea by clear-sky insolation before noon, with the opposite contrast before sunrise caused by evening rainfall-induced "sprinkler"-like land cooling (different from the extratropical infrared cooling on clear nights). Thus, unlike the extratropics, the diurnal cycle over the IMC is more important in the rainy season. The intraseasonal, seasonal to annual, and interannual climate variabilities appear as amplitude modulations of the diurnal cycle. For example, in Jawa and Bali the rainy season is the southern hemispheric summer, because land heating in the clear morning and water vapor transport by afternoon sea breeze is strongest in the season of maximum insolation. During El Niño, cooler sea water surrounding the IMC makes morning maritime convection and rainfall weaker than normal. Because the diurnal cycle is almost the only mechanism generating convective clouds systematically near the equator with little cyclone activity, the local annual rainfall amount in the tropics is a steeply decreasing function of coastal distance ( e-folding scale 100-300 km), and regional annual rainfall is an increasing function of "coastline density" (coastal length/land area) measured at a horizontal resolution of 100 km. The coastline density effect explains

  1. In situ cloud and aerosol measurements over Coastal Antarctica during intensive field campaigns in 2010, 2011 and 2015

    NASA Astrophysics Data System (ADS)

    O'Shea, Sebastian; Choularton, Tom; Flynn, Michael; Bower, Keith; Gallagher, Martin; Fleming, Zoe; Listowski, Constantino; Kirchgaessner, Amelie; Ladkin, Russell; Lachlan-Cope, Tom; Crosier, Jonathan

    2017-04-01

    Few direct measurements have been made of Antarctic aerosol and cloud properties. As a result, a number of studies have suggested they are poorly represented within weather/climate models. This has important consequences for predictions of the mass balance of the Antarctic ice sheet and both weather patterns in the region and worldwide. In situ measurements of cloud and aerosol properties were collected over the Antarctic Peninsula, coastal continent and Weddell Sea during intensive observation periods in 2010, 2011 and 2015. Airborne measurements were collected using British Antarctic Survey's instrumented Twin Otter research aircraft for all 3 campaigns and additional ground based measurements were made at Halley's Clean Air Sector Laboratory in 2015. This presentation will focus on the aerosol measurements from these intensive observation periods. The aerosol in the region was found to have strong vertical gradients and to be hygroscopic in nature. The hygroscopicity parameter, κ had a mean value during the 2015 campaign of 0.69, which is consistent with other remote marine locations that are dominated by sea spray emissions. Aerosol properties will be investigated in terms of their air mass history. The relative contribution of emissions from the Antarctic Continent, sea ice and Sea/Ocean regions will be examined. The ice nucleating properties of the aerosol will also be discussed.

  2. Survival, Continence and Potency (SCP) recovery after radical retropubic prostatectomy: a long-term combined evaluation of surgical outcomes.

    PubMed

    Schiavina, R; Borghesi, M; Dababneh, H; Pultrone, C V; Chessa, F; Concetti, S; Gentile, G; Vagnoni, V; Romagnoli, D; Della Mora, L; Rizzi, S; Martorana, G; Brunocilla, E

    2014-12-01

    To offer a comprehensive account of surgical outcomes on a defined series of patients treated with radical retropubic prostatectomy (RRP) for prostate cancer in a single European Center after 5-year minimum follow-up according to the Survival, Continence and Potency (SCP) system. We evaluated our Institutional database of patients who underwent RRP from November 1995 to September 2008. Oncological and functional outcomes were reported according to the recently proposed SCP system. The 5- and 10-year biochemical recurrence-free survival rates were 80.1% and 55.8%, respectively. At the end of follow-up, 611 (78.5%) patients were fully continent (C0), 107 (13.8%) used 1 pad for security (C1) and 60 (7.7%) patients were incontinent (C2). Of the 112 patients who underwent nerve-sparing RRP, 22 (19.6%) were fully potent without aids (P0), 13 (11.6%) were potent with assumption of PDE-5 inhibitors (P1) and 77 (68.8%) experienced erectile dysfunction (P2). The combined SCP outcomes were reported together only in 95 (12.2%) evaluable patients. In patients preoperatively continent and potent, who received a nerve-sparing and did not require adjuvant therapy, oncological and functional success was attained by 29 (30.5%) patients. In the subgroup of 508 patients not evaluable for potency recovery, oncological and continence outcomes were obtained in 357 patients (70.3%). Survival, Continence and Potency (SCP) classification offer a comprehensive report of surgical results, even in those patients who do not represent the best category, thus allowing to provide a much more accurate evaluation of outcomes after RP. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Exploring the Causes of Mid-Holocene Drought in the Rocky Mountains Using Hydrologic Forward Models

    NASA Astrophysics Data System (ADS)

    Meador, E.; Morrill, C.

    2017-12-01

    We present a quantitative model-data comparison for mid-Holocene (6 ka) lake levels in the Rocky Mountains, with the goals of assessing the skill coupled climate models and hydrologic forward models in simulating climate change and improving our understanding of the factors causing past changes in water resources. The mid-Holocene climate in this area may in some ways be similar to expected future climate, thus improved understanding of the factors causing past changes in water resources have the potential to aid in the process of water allocation for large areas that share a relatively small water source. This project focuses on Little Windy Hill Pond in the Medicine Bow Forest in the Rocky Mountains in southern Wyoming. We first calibrated the Variable Infiltration Capacity (VIC) catchment hydrologic model and the one-dimensional Hostetler Bartlein lake energy-balance model to modern observations, using U.S. Geological Survey stream discharge data and Snow Telemetry (SNOTEL) data to ensure appropriate selection of model parameters. Once the models were calibrated to modern conditions, we forced them with output from eight mid-Holocene coupled climate model simulations completed as part of the Coupled Model Intercomparison Project, Phase 5. Forcing from nearly all of the CMIP5 models generates intense, short-lived droughts for the mid-Holocene that are more severe than any we modeled for the past six decades. The severity of the mid-Holocene droughts could be sufficient, depending on sediment processes in the lake, to account for low lake levels recorded by loss-on-ignition in sediment cores. Our preliminary analysis of model output indicates that the combined effects of decreased snowmelt runoff and increased summer lake evaporation cause low mid-Holocene lake levels. These factors are also expected to be important in the future under anthropogenic climate change.

  4. The early to mid-Miocene environment of Antarctica

    NASA Astrophysics Data System (ADS)

    Ashworth, A. C.; Lewis, A.

    2012-12-01

    Paleoecological studies in the Transantarctic Mountains of the McMurdo region provide evidence that the climate was both warmer and wetter in the early to mid-Miocene than it was during the late Miocene. The climate change was accompanied by a shift from wet- to cold-based glaciation in the TAM and the probable growth of the polar ice sheet. Terrestrial and freshwater aquatic fossil assemblages from the Friis Hills (77°S) and the Olympus Range (77°S), with endpoint 40Ar/39Ar ages on tephras of 19.76 Ma and 14.07 Ma, respectively, indicate climatic cooling during the interval. At c.14 Ma, the temperature dropped below the threshold required to support the plants and insects of a tundra biome, and they became extinct. This interpretation is supported by pollen studies from Ross Sea cores. The extinction of the tundra biota on the continent appears to have been time-transgressive, occurring at 12.8 Ma on the Antarctic Peninsula. Evidence of climatic cooling from early to mid-Miocene is based on a decrease in biodiversity. During interglacial phases of the early Miocene, the poorly drained valley of the Friis Hills supported a sexually-reproducing moss community dominated by Campylium cf. polygamum, which today grows on the margins of lakes and in soil between boulders. Wood and leaves of Nothofagus (Southern Beech), and the seeds of at least five other angiosperm species are preserved as fossils. In addition, there are abundant megaspores and spiny, curved leaves of the aquatic lycopod Isoetes (Quillwort), as well as chitinous remains of curculionid beetles and Chironomidae (midges). During glacial phases, the only fossils found are Nothofagus leaves of a species which appears to be different than that associated with the interglacial phases. Pollen supports the interpretation that there was more than one species of Nothofagus in the vegetation. The types and numbers of species indicate that the vegetation was a shrub tundra. The closest modern analog for the fossil

  5. Plant community composition after 75 years of sustained grazing intensity treatments in shortgrass steppe

    USDA-ARS?s Scientific Manuscript database

    Plant community responses to livestock grazing lack conformity across studies, even those conducted within similar ecosystems. Variability in outcomes is often related to the strong influences of short-term weather patterns, mid-term climatic cycles, differences in the timing and intensity of grazin...

  6. Methods and apparatus for mid-infrared sensing

    DOEpatents

    Lin, Pao Tai; Cai, Yan; Agarwal, Anuradha Murthy; Kimerling, Lionel C.

    2015-06-02

    A chip-scale, air-clad semiconductor pedestal waveguide can be used as a mid-infrared (mid-IR) sensor capable of in situ monitoring of organic solvents and other analytes. The sensor uses evanescent coupling from a silicon or germanium waveguide, which is highly transparent in the mid-IR portion of the electromagnetic spectrum, to probe the absorption spectrum of fluid surrounding the waveguide. Launching a mid-IR beam into the waveguide exposed to a particular analyte causes attenuation of the evanescent wave's spectral components due to absorption by carbon, oxygen, hydrogen, and/or nitrogen bonds in the surrounding fluid. Detecting these changes at the waveguide's output provides an indication of the type and concentration of one or more compounds in the surrounding fluid. If desired, the sensor may be integrated onto a silicon substrate with a mid-IR light source and a mid-IR detector to form a chip-based spectrometer.

  7. Measurement of Dynamic Urethral Pressures with a High Resolution Manometry System in Continent and Incontinent Women

    PubMed Central

    Kirby, Anna C; Tan-Kim, Jasmine; Nager, Charles W.

    2015-01-01

    Objectives Female stress urinary incontinence (SUI) is caused by urethral dysfunction during dynamic conditions, but current technology has limitations in measuring urethral pressures under dynamic conditions. An 8-French high resolution manometry catheter (HRM) currently in clinical use in gastroenterology may accurately measure urethral pressures under dynamic conditions because it has a 25ms response rate and circumferential pressure sensors along the length of the catheter (ManoScan® ESO, Given Imaging). We evaluated the concordance, repeatability, and tolerability of this catheter. Methods We measured resting, cough, and strain maximum urethral closure pressures (MUCPs) using HRM and measured resting MUCPs with water perfusion side-hole catheter urethral pressure profilometry (UPP) in 37 continent and 28 stress incontinent subjects. Maneuvers were repeated after moving the HRM catheter along the urethral length to evaluate whether results depend on catheter positioning. Visual analog pain scores evaluated the comfort of HRM compared to UPP. Results The correlation coefficient for resting MUCPs measured by HRM vs. UPP was high (r = 0.79, p<0.001). Repeatability after catheter repositioning was high for rest, cough, and strain with HRM: r= 0.92, 0.89, and 0.89. Mean MUCPs (rest, cough, strain) were higher in continent than incontinent subjects (all p < 0.001) and decreased more in incontinent subjects than continent subjects during cough and strain maneuvers compared to rest. Conclusions This preliminary study shows that HRM is concordant with standard technology, repeatable, and well tolerated in the urethra. Incontinent women have more impairment of their urethral closure pressures during cough and strain than continent women. PMID:25185595

  8. Measurement of dynamic urethral pressures with a high-resolution manometry system in continent and incontinent women.

    PubMed

    Kirby, Anna C; Tan-Kim, Jasmine; Nager, Charles W

    2015-01-01

    Female stress urinary incontinence is caused by urethral dysfunction during dynamic conditions, but current technology has limitations in measuring urethral pressures under these conditions. An 8-French high-resolution manometry (HRM) catheter currently in clinical use in gastroenterology may accurately measure urethral pressures under dynamic conditions because it has a 25-millisecond response rate and circumferential pressure sensors along the length of the catheter (ManoScan ESO; Given Imaging, Yoqneam, Israel). We evaluated the concordance, repeatability, and tolerability of this catheter. We measured resting, cough, and strain maximum urethral closure pressures (MUCPs) using HRM and measured resting MUCPs with water-perfusion side-hole catheter urethral pressure profilometry (UPP) in 37 continent and 28 stress-incontinent subjects. Maneuvers were repeated after moving the HRM catheter along the urethral length to evaluate whether results depend on catheter positioning. Visual analog pain scores evaluated the comfort of HRM compared to UPP. The correlation coefficient for resting MUCPs measured by HRM versus UPP was high (r = 0.79, P < 0.001). Repeatability after catheter repositioning was high for rest, cough, and strain with HRM: r = 0.92, 0.89, and 0.89. Mean MUCPs (rest, cough, and strain) were higher in continent than in incontinent subjects (all P < 0.001) and decreased more in incontinent subjects than in continent subjects during cough and strain maneuvers compared to rest. This preliminary study shows that HRM is concordant with standard technology, repeatable, and well tolerated in the urethra. Incontinent women have more impairment of their urethral closure pressures during cough and strain than continent women.

  9. National audit of continence care: laying the foundation.

    PubMed

    Mian, Sarah; Wagg, Adrian; Irwin, Penny; Lowe, Derek; Potter, Jonathan; Pearson, Michael

    2005-12-01

    National audit provides a basis for establishing performance against national standards, benchmarking against other service providers and improving standards of care. For effective audit, clinical indicators are required that are valid, feasible to apply and reliable. This study describes the methods used to develop clinical indicators of continence care in preparation for a national audit. To describe the methods used to develop and test clinical indicators of continence care with regard to validity, feasibility and reliability. A multidisciplinary working group developed clinical indicators that measured the structure, process and outcome of care as well as case-mix variables. Literature searching, consensus workshops and a Delphi process were used to develop the indicators. The indicators were tested in 15 secondary care sites, 15 primary care sites and 15 long-term care settings. The process of development produced indicators that received a high degree of consensus within the Delphi process. Testing of the indicators demonstrated an internal reliability of 0.7 and an external reliability of 0.6. Data collection required significant investment in terms of staff time and training. The method used produced indicators that achieved a high degree of acceptance from health care professionals. The reliability of data collection was high for this audit and was similar to the level seen in other successful national audits. Data collection for the indicators was feasible to collect, however, issues of time and staffing were identified as limitations to such data collection. The study has described a systematic method for developing clinical indicators for national audit. The indicators proved robust and reliable in primary and secondary care as well as long-term care settings.

  10. Continent-Ocean Interactions Within East Asian Marginal Seas

    NASA Astrophysics Data System (ADS)

    Clift, Peter; Kuhnt, Wolfgang; Wang, Pinxian; Hayes, Dennis

    The study of the complex interactions between continents and oceans has become a leading area for 21st century earth cience. In this volume, continent—ocean interactions in tectonics, arc-continent collision, sedimentology, and climatic volution within the East Asian Marginal Seas take precedence. Links between oceanic and continental climate, the sedimentology of coastal and shelf areas, and the links between deformation of continental and oceanic lithosphere are also discussed. As an introduction to the science presented throughout the volume, Wang discusses many of the possible interactions between the tectonic evolution of Asia and both regional and global climate. He speculates that uplift of central Asia in the Pliocene may have triggered the formation of many of the major rivers that drain north through Siberia into the Arctic Ocean. He also argues that it is the delivery of this fresh water that allows the formation of sea ice in that area and triggered the start of Northern Hemispheric glaciation. This may be one of the most dramatic ways in which Asia has shaped the Earth's climate and represents an alternative to the other competing models that have previously emphasized the role of oceanic gateway closure in Central America. Moreover, his proposal for major uplift of at least part of Tibet and Mongolia as late as the Pliocene, based on the history of drainage evolution in Siberia, supports recent data from the southern Tarim Basin and from the Qilian Shan and Qaidam and Jiuxi Basins in northeast Tibet that indicate surface uplift at that time. Constraining the timing and patterns of Tibetan surface uplift is crucial to testing competing models for strain accommodation in Asia following India—Asia collision.

  11. Integrated low-intensity biofeedback therapy in fecal incontinence: evidence that "good" in-home anal sphincter exercise practice makes perfect.

    PubMed

    Vasant, D H; Solanki, K; Balakrishnan, S; Radhakrishnan, N V

    2017-01-01

    Biofeedback therapy (BFT) is an established treatment for fecal incontinence (FI), with access often being restricted to tertiary centers due to resources and the perceived requirement for high-intensity regimes. However, the optimal regime remains unknown. We evaluated outcomes from our low-intensity integrated BFT program in a secondary care center. Outcomes of our BFT service for FI were evaluated retrospectively. Response was defined by ≥50% improvement in FI frequency from baseline or complete continence. Responders were compared to non-responders for factors including symptoms, manometry data, sphincter exercise technique and duration of practice, and the number and frequency of sessions. Where patients dropped out, outcomes and the reason for dropout were obtained retrospectively. Fecal incontinence patients (n=205, median 62 years, 72% female) attended a median (IQR) 3 (2) BFT sessions with 55 (36) days between visits. Overall, 146/205 (71%) responded with 97/205 (47%) achieving continence. Fecal incontinence frequency improved dramatically in completed cases (P=0.000). While non-response was associated with males (P=0.03) and dropout (P=0.000), "good" anal sphincter exercise technique (P=0.008) and longer in-home practice (P=0.007) and more sessions (P=0.04) were associated with response. Dropout rate was 80/205 (39%), with the reason for dropout being obtained in 80%. Despite low-intensity BFT, comparable outcomes to data from tertiary centers were achieved. Our data emphasize the importance of technique and in-home practice of anal sphincter exercises. Customizing BFT intensity based on predictive factors and encouraging in-home practice may optimize outcomes, reduce dropout rates, and rationalize resources. © 2016 John Wiley & Sons Ltd.

  12. Mid-Space-Independent Deformable Image Registration

    PubMed Central

    Aganj, Iman; Iglesias, Juan Eugenio; Reuter, Martin; Sabuncu, Mert Rory; Fischl, Bruce

    2017-01-01

    Aligning images in a mid-space is a common approach to ensuring that deformable image registration is symmetric – that it does not depend on the arbitrary ordering of the input images. The results are, however, generally dependent on the mathematical definition of the mid-space. In particular, the set of possible solutions is typically restricted by the constraints that are enforced on the transformations to prevent the mid-space from drifting too far from the native image spaces. The use of an implicit atlas has been proposed as an approach to mid-space image registration. In this work, we show that when the atlas is aligned to each image in the native image space, the data term of implicit-atlas-based deformable registration is inherently independent of the mid-space. In addition, we show that the regularization term can be reformulated independently of the mid-space as well. We derive a new symmetric cost function that only depends on the transformation morphing the images to each other, rather than to the atlas. This eliminates the need for anti-drift constraints, thereby expanding the space of allowable deformations. We provide an implementation scheme for the proposed framework, and validate it through diffeomorphic registration experiments on brain magnetic resonance images. PMID:28242316

  13. Feldspar basalts in lunar soil and the nature of the lunar continents

    NASA Technical Reports Server (NTRS)

    Reid, A. M.; Ridley, W. I.; Harmon, R. S.; Warner, J.; Brett, R.; Jakes, P.; Brown, R. W.

    1974-01-01

    It is found that 25% on the Apollo-14 glasses have the same composition as the glasses in two samples taken from the Luna-16 column. The compositions are equivalent to feldspar basalt and anorthosite gabbro, and are similar to the feldspar basalts identified from Surveyor-7 analysis for lunar continents.

  14. Earthquake Hazard and the Environmental Seismic Intensity (ESI) Scale

    NASA Astrophysics Data System (ADS)

    Serva, Leonello; Vittori, Eutizio; Comerci, Valerio; Esposito, Eliana; Guerrieri, Luca; Michetti, Alessandro Maria; Mohammadioun, Bagher; Mohammadioun, Georgianna C.; Porfido, Sabina; Tatevossian, Ruben E.

    2016-05-01

    The main objective of this paper was to introduce the Environmental Seismic Intensity scale (ESI), a new scale developed and tested by an interdisciplinary group of scientists (geologists, geophysicists and seismologists) in the frame of the International Union for Quaternary Research (INQUA) activities, to the widest community of earth scientists and engineers dealing with seismic hazard assessment. This scale defines earthquake intensity by taking into consideration the occurrence, size and areal distribution of earthquake environmental effects (EEE), including surface faulting, tectonic uplift and subsidence, landslides, rock falls, liquefaction, ground collapse and tsunami waves. Indeed, EEEs can significantly improve the evaluation of seismic intensity, which still remains a critical parameter for a realistic seismic hazard assessment, allowing to compare historical and modern earthquakes. Moreover, as shown by recent moderate to large earthquakes, geological effects often cause severe damage"; therefore, their consideration in the earthquake risk scenario is crucial for all stakeholders, especially urban planners, geotechnical and structural engineers, hazard analysts, civil protection agencies and insurance companies. The paper describes background and construction principles of the scale and presents some case studies in different continents and tectonic settings to illustrate its relevant benefits. ESI is normally used together with traditional intensity scales, which, unfortunately, tend to saturate in the highest degrees. In this case and in unpopulated areas, ESI offers a unique way for assessing a reliable earthquake intensity. Finally, yet importantly, the ESI scale also provides a very convenient guideline for the survey of EEEs in earthquake-stricken areas, ensuring they are catalogued in a complete and homogeneous manner.

  15. How short are ultra short light pulses? (looking back to the mid sixties)

    NASA Astrophysics Data System (ADS)

    Weber, H. P.; Dändliker, R.

    2010-09-01

    With the arrival of mode locking for Q-switched lasers to generate ultra short light pulses, a method to measure their expected time duration in the psec range was needed. A novel method, based on an intensity correlation measurement using optical second harmonic generation, was developed. Other reported approaches for the same purpose were critically analysed. Theoretical and subsequent experimental studies lead to surprising new insight into the ultra fast temporal behaviour of broadband laser radiation: Any non mode locked multimode emission of a laser consists of random intensity fluctuations with duration of the total inverse band width of emitted radiation. However, it was shown, that with mode locking isolated ultra short pulses of psec duration can be generated. This article summarizes activities performed in the mid sixties at the University of Berne, Switzerland.

  16. Continued improvement of perioperative, pathological and continence outcomes during 700 robot-assisted radical prostatectomies.

    PubMed

    Zorn, Kevin C; Wille, Mark A; Thong, Alan E; Katz, Mark H; Shikanov, Sergey A; Razmaria, Aria; Gofrit, Ofer N; Zagaja, Gregory P; Shalhav, Arieh L

    2009-08-01

    Several robot-assisted radical prostatectomy (RARP) series have reviewed the impact of the initial learning curve on perioperative outcomes. However, little is known about the impact of experience on urinary and sexual outcomes. Herein, we review the perioperative, pathological and functional outcomes of our initial 700 consecutive procedures with at least 1 year follow up. From 2003-2006, 700 consecutive men underwent RARP at a single, academic institution. Perioperative data and pathologic outcomes were prospectively collected. Validated, UCLA-PCI-SF36v2 quality-of-life questionnaires were also obtained at 1, 3, 6 and 12 months following surgery. Outcomes between groups (cases 1-300, 301-500, and 501-700) were compared. Mean operative time (OT) and blood loss significantly decreased during the experience (286, 198, 190 min; p or=7 in 24%, 40%, 44%; p continence rate was 81% when self reported and 62% when assessed by the UCLA-PCI-SF36v2 questionnaire in the initial group. Continence rates improved to 93% and 75%, respectively, for cases 501-700 (p continence rates between consecutive case groups was observed at all postoperative time points. Potency rate was 83% (bilateral nerve preservation) and 56% (unilateral nerve preservation) at 12 months when self reported and 63% and 37% respectively by the UCLA-PCI-SF36v2. No significant differences in sexual function were noted with increased experience. A prolonged learning curve is observed for EBL, OT and pT2-PSM. In addition, to the best of our knowledge, this is first series demonstrating a continued improvement in urinary continence with increased RARP experience.

  17. Intercomparison of mid latitude storm diagnostics (IMILAST)

    NASA Astrophysics Data System (ADS)

    Neu, U.

    2009-04-01

    Diagnostics of the observed and projection of the future changes of extratropical storms are a key issue e.g. for insurance companies, risk management and adaptation planning. Storm-associated damages are amongst the highest losses due to natural disasters in the mid-latitudes. Therefore the knowledge of the future variability and change in extratropical cyclone frequency, intensity and track locations is crucial for the strategic planning and minimization of the disaster impacts. Future changes in the total number of storms might be small but major signals could occur in the characteristics of cyclone life cycle such as intensity, life time, track locations. The quantification of such trends is not independent from the methodologies for storm track detection applied to observational data and models. Comparison of differences in cyclone characteristics obtained using different methods from a single data set may be as large as or even exceed the differences between the results derived from different data sets using a single methodology. Even more, the metrics used become particularly sensitive, resulting in the fact that scientific studies may find seemingly contradictory results based on the same datasets. For users of storm track analyses and projections the results are very difficult to interprete. Thus, it would be very helpful if the research community would provide information in a kind of "handbook" which contains definitions and a description of the available different identification and tracking schemes as well as of the parameters used for the quantification of cyclone activity. It cannot be expected that there is an optimum or standard scheme that fulfills all needs. Rather, a proper knowledge about advantages and restrictions of different schemes must be obtained to be able to provide a synthesis of results rather than puzzling the scientific and the general public with apparently contradicing statements. The project IMILAST aims at providing a

  18. Power Doppler of the urethra in continent or incontinent, pre- and postmenopausal women.

    PubMed

    Jármy-Di Bella, Z I; Girão, M J; Sartori, M F; Di Bella Júnior, V; Lederman, H M; Baracat, E C; Lima, G R

    2000-06-01

    Urethral pressure should exceed bladder pressure, both at rest and on stress, for urinary continence to occur. A decrease in urethral pressure is a major factor explaining the pathogenesis of urinary incontinence. A number of elements, such as smooth and striated periurethral muscles, and connective, vascular and elastic tissues, contribute to urethral pressure. The periurethral vessels are influenced by hormonal changes during the menstrual cycle, during pregnancy and postmenopause. We studied the periurethral vessels in 97 women, 57 of whom were incontinent and 40 continent, using power color Doppler velocimetry. The number of periurethral vessels, systolic peak, minimum diastolic values, pulsatility and resistance indexes, as well as systolic-diastolic ratio, were assessed. Statistically significant differences were found between incontinent women in the premenopausal period and those in the postmenopausal period, regarding the number of periurethral vessels, systolic peak, minimum diastolic values, pulsatility and resistance indexes.

  19. Mid-Western Educational Researcher, 1999.

    ERIC Educational Resources Information Center

    Bainer, Deborah L., Ed.; Kramer, Gene A., Ed.; Smith, Richard M., Ed.

    1999-01-01

    Volume 12 of the Mid-Western Educational Researcher contains four issues. The first issue includes kick-off, keynote, luncheon, and presidential addresses from the annual meeting of the Mid-Western Educational Research Association (MWERA), held in Chicago, Illinois, in October 1998. Issue 3 is the program for MWERA's annual meeting in Chicago,…

  20. Mid-infrared supercontinuum covering the 1.4-13.3 μm molecular fingerprint region using ultra-high NA chalcogenide step-index fibre

    NASA Astrophysics Data System (ADS)

    Petersen, Christian Rosenberg; Møller, Uffe; Kubat, Irnis; Zhou, Binbin; Dupont, Sune; Ramsay, Jacob; Benson, Trevor; Sujecki, Slawomir; Abdel-Moneim, Nabil; Tang, Zhuoqi; Furniss, David; Seddon, Angela; Bang, Ole

    2014-11-01

    The mid-infrared spectral region is of great technical and scientific interest because most molecules display fundamental vibrational absorptions in this region, leaving distinctive spectral fingerprints. To date, the limitations of mid-infrared light sources such as thermal emitters, low-power laser diodes, quantum cascade lasers and synchrotron radiation have precluded mid-infrared applications where the spatial coherence, broad bandwidth, high brightness and portability of a supercontinuum laser are all required. Here, we demonstrate experimentally that launching intense ultra-short pulses with a central wavelength of either 4.5 μm or 6.3 μm into short pieces of ultra-high numerical-aperture step-index chalcogenide glass optical fibre generates a mid-infrared supercontinuum spanning 1.5 μm to 11.7 μm and 1.4 μm to 13.3 μm, respectively. This is the first experimental demonstration to truly reveal the potential of fibres to emit across the mid-infrared molecular ‘fingerprint region’, which is of key importance for applications such as early cancer diagnostics, gas sensing and food quality control.

  1. Evaluation of MidIR fibre optic reflectance: Detection limit, reproducibility and binary mixture discrimination

    NASA Astrophysics Data System (ADS)

    Sessa, Clarimma; Bagán, Héctor; García, José Francisco

    2013-11-01

    MidIR fibre optic reflectance (MidIR-FORS) is a promising analytical technique in the field of science conservation, especially because it is non-destructive. Another advantage of MidIR-FORS is that the obtained information is representative, as a large amount of spectral data can be collected. Although the technique has a high potential and is almost routinely applied, its quality parameters have not been thoroughly studied in the specific application of analysis of artistic materials. The objective of this study is to evaluate the instrumental capabilities of MidIR-FORS for the analysis of artwork materials in terms of detection limit, reproducibility, and mixture characterisation. The study has been focused on oil easel painting and several paints of known composition have been analysed. Paint layers include blue pigments not only because of their important role along art history, but also because their physical and spectroscopic characteristics allow a better evaluation of the MidIR-FORS capabilities. The results of the analysis indicate that MidIR-FORS supplies a signal affected by different factors, such as the optical, morphological and physical properties of the surface, in addition to the composition of materials analysed. Consequently, the detection limits established are relatively high for artistic objects (Prussian blue - PB 2.1-6.5%; Phthalocyanine blue - Pht 6.3-10.2%; synthetic Ultramarine blue - UM 12.1%) and may therefore lead to an incomplete description of the artwork. Reproducibility of the technique over time and across surface has been determined. The results show that the major sources of dispersion are the heterogeneity of the pigments distribution, physical features, and band shape distortions. The total dispersion is around 4% for the most intense bands (oil) and increases up to 26% when weak or overlapped bands are considered (PB, Pht, UM). The application of different pre-treatments (cutoff of fibres absorption, Savizky-Golay smoothing

  2. Mid-space-independent deformable image registration.

    PubMed

    Aganj, Iman; Iglesias, Juan Eugenio; Reuter, Martin; Sabuncu, Mert Rory; Fischl, Bruce

    2017-05-15

    Aligning images in a mid-space is a common approach to ensuring that deformable image registration is symmetric - that it does not depend on the arbitrary ordering of the input images. The results are, however, generally dependent on the mathematical definition of the mid-space. In particular, the set of possible solutions is typically restricted by the constraints that are enforced on the transformations to prevent the mid-space from drifting too far from the native image spaces. The use of an implicit atlas has been proposed as an approach to mid-space image registration. In this work, we show that when the atlas is aligned to each image in the native image space, the data term of implicit-atlas-based deformable registration is inherently independent of the mid-space. In addition, we show that the regularization term can be reformulated independently of the mid-space as well. We derive a new symmetric cost function that only depends on the transformation morphing the images to each other, rather than to the atlas. This eliminates the need for anti-drift constraints, thereby expanding the space of allowable deformations. We provide an implementation scheme for the proposed framework, and validate it through diffeomorphic registration experiments on brain magnetic resonance images. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. Simulating intracrater ash recycling during mid-intensity explosive activity: high temperature laboratory experiments on natural basaltic ash

    NASA Astrophysics Data System (ADS)

    D'Oriano, Claudia; Pompilio, Massimo; Bertagnini, Antonella; Cioni, Raffaello; Pichavant, Michel

    2010-05-01

    Direct observations of mid-intensity eruptions, in which a huge amount of ash is generated, indicate that ash recycling is quite common. The recognition of juvenile vs. recycled fragments is not straightforward, and no unequivocal, widely accepted criteria exist to support this. The presence of recycled glassy fragments can hide primary magmatic information, introducing bias in the interpretations of the ongoing magmatic and volcanic activity. High temperature experiments were performed at atmospheric pressure on natural samples to investigate the effects of reheating on morphology, texture and composition of volcanic ash. Experiments simulate the transformation of juvenile glassy fragments that, falling into the crater or in the upper part of the conduit, are recycled by following explosions. Textural and compositional modifications obtained in laboratory are compared with similar features observed in natural samples in order to identify some main general criteria to be used for the discrimination of recycled material. Experiments were carried out on tephra produced during Strombolian activity, fire fountains and continuous ash emission at Etna, Stromboli and Vesuvius. Coarse glassy clasts were crushed in a nylon mortar in order to create an artificial ash, and then sieved to select the size interval of 1-0.71 mm. Ash shards were put in a sealed or open quartz tube, in order to prevent or to reproduce effects of air oxidation. The tube was suspended in a HT furnace at INGV-Pisa and kept at different temperatures (up to to 1110°C) for increasing time (0.5-12 hours). Preliminary experiments were also performed under gas flux conditions. Optical and electron microscope observations indicate that high temperature and exposure to the air induce large modifications on clast surface, ranging from change in color, to incipient plastic deformation till complete sintering. Significant change in color of clasts is strictly related to the presence of air, irrespective of

  4. Pandemic Vibrio parahaemolyticus O3:K6 on the American continent

    PubMed Central

    Velazquez-Roman, Jorge; León-Sicairos, Nidia; de Jesus Hernández-Díaz, Lucio; Canizalez-Roman, Adrian

    2014-01-01

    Vibrio parahaemolyticus is one of the most important seafood-borne bacterial in recent years and is the leading causal agent of human acute gastroenteritis, primarily following the consumption of raw, undercooked or mishandled marine products. Until 1996, infections caused by V. parahaemolyticus were generally associated with diverse serovars. However, in February 1996, a unique serovar (O3:K6) of V. parahaemolyticus with specific genetic markers (tdh, toxRS/New and/or orf8) appeared abruptly in Kolkata, India. In subsequent years, O3:K6 isolates similar to those isolated in Kolkata have been reported from food borne outbreaks in Southeast Asia, as well as in the Atlantic and Gulf coasts of the United States (U.S). More recently, there have been reports in Europe, Africa and Central and South America. Specifically, in the American continent, some countries have reported cases of gastroenteritis due to the pandemic O3:K6 strain and its serovariants; the pandemic strain was first detected in Peru (1996, >100 cases), subsequently spreading to Chile in 1998 (>16,804 human cases), to the U.S. in 1998 (>700 cases), to Brazil in 2001 (>18 cases) and to Mexico in 2004 (>1200 cases). The arrival of the pandemic clone on the American continent may have resulted in a significant shift on the epidemic dynamics of V. parahaemolyticus. However, although O3:K6 is the predominant serovar of the recognized clinical strains in some countries in the Americas, a decrease in clinical cases caused by O3:K6 and an increase in cases associated with a new serotype (O3:K59, Chile) have been recently reported. The emergence and worldwide dissemination of O3:K6 and other pandemic strains since 1996 have come to represent a threat to public health and should concern health authorities. This review focuses on the presence, distribution and virulence factors of the V. parahaemolyticus O3:K6 pandemic clone and its serovariants in clinical and environmental strains on the American continent. PMID

  5. Contrasting introduction scenarios among continents in the worldwide invasion of the banana fungal pathogen Mycosphaerella fijiensis.

    PubMed

    Robert, S; Ravigne, V; Zapater, M-F; Abadie, C; Carlier, J

    2012-03-01

    Reconstructing and characterizing introduction routes is a key step towards understanding the ecological and evolutionary factors underlying successful invasions and disease emergence. Here, we aimed to decipher scenarios of introduction and stochastic demographic events associated with the global spread of an emerging disease of bananas caused by the destructive fungal pathogen Mycosphaerella fijiensis. We analysed the worldwide population structure of this fungus using 21 microsatellites and 8 sequence-based markers on 735 individuals from 37 countries. Our analyses designated South-East Asia as the source of the global invasion and supported the location of the centre of origin of M. fijiensis within this area. We confirmed the occurrence of bottlenecks upon introduction into other continents followed by widespread founder events within continents. Furthermore, this study suggested contrasting introduction scenarios of the pathogen between the African and American continents. While potential signatures of admixture resulting from multiple introductions were detected in America, all the African samples examined seem to descend from a single successful founder event. In combination with historical information, our study reveals an original and unprecedented global scenario of invasion for this recently emerging disease caused by a wind-dispersed pathogen. © 2012 Blackwell Publishing Ltd.

  6. Intense Convective Activity Over Northern Bay of Bengal during Late Southwest Monsoon

    NASA Astrophysics Data System (ADS)

    Mathew, S.; Venkatesan, R.; Natesan, U.; G, L.

    2016-02-01

    Warming of the northern Bay of Bengal during late southwest monsoon was very much influenced by the intensity of freshening by river discharges. The inter-annual variability of freshening and associated warming was analyzed for 2011 to 2015, with the help of in-situ data obtained from the moored buoys deployed at specific locations in northern Bay of Bengal. The shoaling of mixed layer depth associated with the advection of freshwaters has favored intense warming and supported convective activity thereby. The year 2011 recorded highest freshening with salinity touched as low as 21.3 p.s.u.; with the heavy river discharges, resulted from intense rainfall over catchment areas of rivers that discharged into the bay, due to positive Indian Ocean Dipole and La-Nina affect. It has resulted in intense warming of the surface temperature by 2°C, which persisted for nearly three weeks. The year 2014 was least fresh, with no signature of freshening and associated warming. The latent heat flux term computed from the moored buoy using the COARE 3.5 algorithm showed increased loss of latent heat flux during the late monsoon associated with the warming. It directly supported increased convective activity and delayed the withdrawal of monsoon activity from Indian sub-continent. Two depressions with intense convective activity formed over bay during September of 2011 which delayed the withdrawal of monsoon by three weeks.

  7. Experimental study of faecal continence and colostomy irrigation.

    PubMed

    O'Bichere, A; Sibbons, P; Doré, C; Green, C; Phillips, R K

    2000-07-01

    Colostomy irrigation is a useful method of achieving faecal continence in selected conditions, but remains largely underutilized because it is time consuming. This study investigated the effect of modifying irrigation technique (route, infusion regimen and pharmacological manipulation) on colonic emptying time in a porcine model. An end-colostomy and caecostomy were fashioned in six pigs. Twenty markers were introduced into the caecum immediately before colonic irrigation. Irrigation route (antegrade or retrograde), infusion regimen (tap water, polyethylene glycol (PEG), 1.5 per cent glycine) and pharmacological agent (glyceryl trinitrate (GTN) 0.25 mg/kg, diltiazem 3.9 mg/kg, bisacodyl 0.25 mg/kg) were assigned to each animal at random. Colonic transit was assessed by quantifying cumulative expelled markers (CEM) and stool every hour for 12 h. Mean CEM at 6 h for bisacodyl, GTN and diltiazem were 18.17, 12.17 and zero respectively; all pairwise differences in means were significant (P < 0.001). The difference at 12 h between the two routes (P = 0.001) and three fluids (tap water 6.75, glycine 14.83, PEG 16.33; P < 0. 001) was significant, but not for PEG versus glycine and bisacodyl versus GTN. Cumulative output was significantly more with the antegrade than retrograde route using PEG, but the difference in mean cumulative output for bisacodyl and GTN at 12 h was not significant. Colonic emptying is more efficient with antegrade than retrograde irrigation. PEG and glycine enhance emptying similar to bisacodyl and GTN solution. These findings show promise for improved faecal continence by colostomy irrigation and may justify construction of a Malone conduit at the time of colostomy in selected patients who wish to irrigate. Presented in part to the British Society of Gastroenterology in Glasgow, UK, March 1999, and published in abstract form as Gut 1999; 44(Suppl 1): A135

  8. Mesoscale Convective Complexes (MCCs) over the Indonesian Maritime Continent during the ENSO events

    NASA Astrophysics Data System (ADS)

    Trismidianto; Satyawardhana, H.

    2018-05-01

    This study analyzed the mesoscale convective complexes (MCCs) over the Indonesian Maritime Continent (IMC) during the El Niño/Southern Oscillation (ENSO) events for the the15-year period from 2001 to 2015. The MCCs identified by infrared satellite imagery that obtained from the Himawari generation satellite data. This study has reported that the frequencies of the MCC occurrences at the El Niño and La Niña were higher than that of neutral conditions during DJF. Peak of MCC occurrences during DJF at La Niña and neutral condition is in February, while El Niño is in January. ENSO strongly affects the occurrence of MCC during the DJF season. The existences of the MCC were also accompanied by increased rainfall intensity at the locations of the MCC occurrences for all ENSO events. During JJA seasons, the MCC occurrences are always found during neutral conditions, El Niño and La Niña in Indian Ocean. MCC occurring during the JJA season on El Niño and neutral conditions averaged much longer than during the DJF season. In contrast, MCCs occurring in La Niña conditions during the JJA season are more rapidly extinct than during the DJF. It indicates that the influence of MCC during La Niña during the DJF season is stronger than during the JJA season.

  9. Mid South Middle Start: Studies of Three Middle Start Schools in the Mid South Delta

    ERIC Educational Resources Information Center

    Rose, Lea Williams; Cheney, Nancy

    2005-01-01

    These three case studies highlight the implementation and impact of Mid South Middle Start by: (1) contributing toward an in-depth understanding of what it means to be a school implementing Middle Start; (2) describing a holistic portrait of the schools' participation in Mid South Middle Start; and (3) assisting the Academy for Educational…

  10. COMPARISON OF MID-WESTERN AND MID-ATLANTIC REGIONS EXPOSURE CRITERIA FOR PETROLEUM AND COMBUSTION BY-PRODUCTS

    EPA Science Inventory

    Regional background levels of exposure to fish from petroleum and combustion by-products were determined for the state of Ohio (mid-Western) and the mid-Atlantic region. Exposures were measured using bile metabolites that fluoresce at 290/335 nm for naphthalene (NAPH)-type compou...

  11. Meteor Shower observations from the Indian Sub-Continent (Visual Photographic and Radio)

    NASA Astrophysics Data System (ADS)

    Dabhade, R.; Savant, V.; Belapure, J.

    2011-01-01

    We review the present status of meteor shower observing from the Indian sub-continent. Some amateur groups are active in visual observations, although they are restricted by the lack of good observing sites. Ham radio appears to be promising as a technique to monitor the major meteor showers in this region. We present radio observations of the 2006 Quadrantids.

  12. The effect of plumes and a free surface on mantle dynamics with continents and self-consistent plate tectonics

    NASA Astrophysics Data System (ADS)

    Jain, Charitra; Rozel, Antoine; Tackley, Paul

    2014-05-01

    Rolf et al. (EPSL, 2012) and Coltice et al. (Science, 2012) investigated the thermal and dynamical influences of continents on plate tectonics and the thermal state of Earth's mantle, but they did not explicitly consider the influence of mantle plumes. When present, strong mantle plumes arising from the deep mantle can impose additional stresses on the continents, thereby facilitating continental rifting (Storey, Nature 1995; Santosh et al., Gondwana Research 2009) and disrupting the supercontinent cycle (Philips and Bunge, Geology 2007). In recent years, several studies have characterized the relation between the location of the plumes and the continents, but with contradicting observations. While Heron and Lowman (GRL, 2010; Tectonophysics, 2011) propose regions where downwelling has ceased (irrespective of overlying plate) as the preferred location for plumes, O'Neill et al. (Gondwana Research, 2009) show an anti-correlation between the average positions of subducting slabs at continental margins, and mantle plumes at continental/oceanic interiors. Continental motion is attributed to the viscous stresses imparted by the convecting mantle and the extent of this motion depends on the heat budget of the mantle. Core-mantle boundary (CMB) heat flux, internal heating from decay of radioactive elements, and mantle cooling contribute to this heat budget. Out of these sources, CMB heat flux is not well defined; however, the recent determination that the core's thermal conductivity is much higher than previously thought requires a CMB heat flow of at least 12 TW (de Koker et al., PNAS 2012; Pozzo et al., Nature 2012; Gomi et al., PEPI 2013), much higher than early estimates of 3-4 TW (Lay et al., Nature 2008). Thus, it is necessary to characterize the effect of increased CMB heat flux on mantle dynamics. In almost all mantle convection simulations, the top boundary is treated as a free-slip surface whereas Earth's surface is a deformable free surface. With a free

  13. Mid-sagittal plane and mid-sagittal surface optimization in brain MRI using a local symmetry measure

    NASA Astrophysics Data System (ADS)

    Stegmann, Mikkel B.; Skoglund, Karl; Ryberg, Charlotte

    2005-04-01

    This paper describes methods for automatic localization of the mid-sagittal plane (MSP) and mid-sagittal surface (MSS). The data used is a subset of the Leukoaraiosis And DISability (LADIS) study consisting of three-dimensional magnetic resonance brain data from 62 elderly subjects (age 66 to 84 years). Traditionally, the mid-sagittal plane is localized by global measures. However, this approach fails when the partitioning plane between the brain hemispheres does not coincide with the symmetry plane of the head. We instead propose to use a sparse set of profiles in the plane normal direction and maximize the local symmetry around these using a general-purpose optimizer. The plane is parameterized by azimuth and elevation angles along with the distance to the origin in the normal direction. This approach leads to solutions confirmed as the optimal MSP in 98 percent of the subjects. Despite the name, the mid-sagittal plane is not always planar, but a curved surface resulting in poor partitioning of the brain hemispheres. To account for this, this paper also investigates an optimization strategy which fits a thin-plate spline surface to the brain data using a robust least median of squares estimator. Albeit computationally more expensive, mid-sagittal surface fitting demonstrated convincingly better partitioning of curved brains into cerebral hemispheres.

  14. Mid-Life Nuances and Negotiations: Narrative Maps and the Social Construction of Mid-Life in Sport and Physical Activity

    ERIC Educational Resources Information Center

    Partington, Elizabeth; Partington, Sarah; Fishwick, Lesley; Allin, Linda

    2005-01-01

    This paper adopts a narrative perspective on the study of mid-life experiences in sport. Different types of stories about sporting mid-life are identified and discussed. Drawing upon the concept of narrative mapping, the potential of these stories to serve as narrative maps for those approaching mid-life is considered. Data from an interview study…

  15. Tm3+-doped lead silicate glass sensitized by Er3+ for efficient 2 μm mid-infrared laser material

    NASA Astrophysics Data System (ADS)

    Zhang, Junjie; Wang, Ning; Guo, Yanyan; Cai, Muzhi; Tian, Ying; Huang, Feifei; Xu, Shiqing

    2018-06-01

    Er3+/Tm3+ co-doped lead silicate glasses with low phonon (953 cm-1) and good thermal stability were synthesized. The 2 μm mid-infrared emission resulting from the 3F4 → 3H6 transition of Tm3+ sensitized by Er3+ has been observed by 808 nm LD pumping. The optimal luminescence intensity was obtained in the sample with 1Tm2O3/2.5Er2O3 co-doped. Moreover, the energy transfer mechanism from Er3+ to Tm3+ ion was analyzed. Absorption and emission cross section have been calculated. The calculated maximum emission cross section of Tm3+ is 2.689 × 10-21 cm2 at 1863 nm. Microparameters of energy transfer between Er3+ and Tm3+ ions have also been analyzed. These results ensure that the prepared Er3+/Tm3+ co-doped lead silicate glasses have excellent spectroscopic properties in mid-infrared region and provide a beneficial guide for mid-infrared laser material.

  16. MAGSAT and aeromagnetic data in the North American continent

    NASA Technical Reports Server (NTRS)

    1981-01-01

    Problems were encountered in deriving a proper reference field to be subtracted from the aeromagnetic data obtained from Project MAGNET. Field models tried thus far do not seem to eliminate properly the main field. The MAGSAT data in the North American continent for the period November 1 to December 22, 1979 are being compiled and compared with MAGNET data. Efforts are being made to eliminate the orbital bias errors. A computer program was developed and successfully tested which computes a topographic profile of the Curie depth isotherm which fits best to the observed vector or scalar field magnetic data.

  17. Association between gestational age and induction-to-abortion interval in mid-trimester pregnancy termination using misoprostol.

    PubMed

    Vitner, Dana; Deutsch, Michael; Paz, Yuri; Khatib, Nizar; Baltiter, Tania; Rosenberg, Shiran; Lowenstein, Lior

    2011-06-01

    The study was aimed to evaluate the effectiveness, outcome, and pain intensity of the vaginal administration of misoprostol for the induction of abortion between 13 and 24 gestational weeks. A retrospective study was conducted at our tertiary medical center from January 2006 to December 2009 on 122 consecutive women who underwent termination of pregnancy (TOP) in the mid-trimester. They were given 400 mcg of vaginal misoprostol every 6h, up to four doses. The induction-to-abortion interval and the level of pain experienced during the process were assessed. Success was defined by the fetus being expelled within 48 h. Vaginal misoprostol was effective in 84% (98/122) of patients. The median duration of the induction-to-abortion interval was 16 (5-48)h. The induction-to-abortion interval was correlated with gestational age, while inversely correlated with parity. A correlation was also found between gestational age and pain intensity at 12h from induction. Misoprostol is safe and effective in mid-trimester abortion induction. The induction-to-abortion interval is shorter and abortion less painful with lower gestational age. Higher parity is also associated with shorter induction to abortion interval. Copyright © 2011. Published by Elsevier Ireland Ltd.

  18. Comparative visual ecophysiology of mid-Atlantic temperate reef fishes

    PubMed Central

    Horodysky, Andrij Z.; Brill, Richard W.; Crawford, Kendyl C.; Seagroves, Elizabeth S.; Johnson, Andrea K.

    2013-01-01

    Summary The absolute light sensitivities, temporal properties, and spectral sensitivities of the visual systems of three mid-Atlantic temperate reef fishes (Atlantic spadefish [Ephippidae: Chaetodipterus faber], tautog [Labridae: Tautoga onitis], and black sea bass [Serranidae: Centropristis striata]) were studied via electroretinography (ERG). Pelagic Atlantic spadefish exhibited higher temporal resolution but a narrower dynamic range than the two more demersal foragers. The higher luminous sensitivities of tautog and black sea bass were similar to other benthic and demersal coastal mid-Atlantic fishes. Flicker fusion frequency experiments revealed significant interspecific differences at maximum intensities that correlated with lifestyle and habitat. Spectral responses of the three species spanned 400–610 nm, with high likelihood of cone dichromacy providing the basis for color and contrast discrimination. Significant day-night differences in spectral responses were evident in spadefish and black sea bass but not tautog, a labrid with characteristic structure-associated nocturnal torpor. Atlantic spadefish responded to a wider range of wavelengths than did deeper-dwelling tautog or black sea bass. Collectively, these results suggest that temperate reef-associated fishes are well-adapted to their gradient of brighter to dimmer photoclimates, representative of their unique ecologies and life histories. Continuing anthropogenic degradation of water quality in coastal environments, at a pace faster than the evolution of visual systems, may however impede visual foraging and reproductive signaling in temperate reef fishes. PMID:24285711

  19. Measuring progress from nationally determined contributions to mid-century strategies

    NASA Astrophysics Data System (ADS)

    Iyer, Gokul; Ledna, Catherine; Clarke, Leon; Edmonds, James; McJeon, Haewon; Kyle, Page; Williams, James H.

    2017-12-01

    The Paris Agreement requires countries to articulate near-term emissions reduction strategies through to 2025 or 2030 by communicating nationally determined contributions (NDCs), as well as encouraging the formulation of long-term low-emission development strategies (Article 4.19)1. In response, many countries have either submitted or are preparing mid-century strategies2. Most NDCs set high-level near-term goals—such as limits on emissions or emissions intensity3—which do not provide information about the extent to which they lay the foundations of technology, infrastructure and institutions for deeper reductions in the future, which is a key question for decision makers. Here, using a state-level model of the US embedded within a global integrated assessment model4,5, we demonstrate that although the US NDC lies on a straight-line emissions pathway towards its mid-century strategy, the resulting energy system transitions involve nonlinear transformations. The rates of capacity additions and capital investments in electricity generation beyond 2025 are more than three times the rates during the next decade. Our results demonstrate the need for global stocktaking exercises to evaluate the NDCs using metrics broader than emissions to better illuminate their effectiveness in addressing the Paris Agreement's long-term goals6,7.

  20. Assessment of Delirium in Intensive Care Unit Patients: Educational Strategies.

    PubMed

    Smith, Judith M; Van Aman, M Nancy; Schneiderhahn, Mary Elizabeth; Edelman, Robin; Ercole, Patrick M

    2017-05-01

    Delirium is an acute brain dysfunction associated with poor outcomes in intensive care unit (ICU) patients. Critical care nurses play an important role in the prevention, detection, and management of delirium, but they must be able to accurately assess for it. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) instrument is a reliable and valid method to assess for delirium, but research reveals most nurses need practice to use it proficiently. A pretest-posttest design was used to evaluate the success of a multimodal educational strategy (i.e., online learning module coupled with standardized patient simulation experience) on critical care nurses' knowledge and confidence to assess and manage delirium using the CAM-ICU. Participants (N = 34) showed a significant increase (p < .001) in confidence in their ability to assess and manage delirium following the multimodal education. No statistical change in knowledge of delirium existed following the education. A multimodal educational strategy, which included simulation, significantly added confidence in critical care nurses' performance using the CAM-ICU. J Contin Nurs Educ. 2017;48(5):239-244. Copyright 2017, SLACK Incorporated.

  1. Mid-infrared Raman amplification and wavelength conversion in dispersion engineered silicon-on-sapphire waveguides

    NASA Astrophysics Data System (ADS)

    Wang, Zhaolu; Liu, Hongjun; Huang, Nan; Sun, Qibing; Li, Xuefeng

    2014-01-01

    Raman amplification based on stimulated Stokes Raman scattering (SSRS) and wavelength conversion based on coherent anti-Stokes Raman scattering (CARS) are theoretically investigated in silicon-on-sapphire (SOS) waveguides in the mid-infrared (IR) region. When the linear phase mismatch Δk is close to zero, the Stokes gain and conversion efficiency drop down quickly due to the effect of parametric gain suppression when the Stokes-pump input ratio is sufficiently large. The Stokes gain increases with the increase of Δk, whereas efficient wavelength conversion needs appropriate Δk under different pump intensities. The conversion efficiency at exact linear phase matching (Δk = 0) is smaller than that at optimal linear phase mismatch by a factor of about 28 dB when the pump intensity is 2 GW cm-2.

  2. A note on the annual cycles of surface heat balance and temperature over a continent. [North America

    NASA Technical Reports Server (NTRS)

    Spar, J.; Crane, G.

    1974-01-01

    A surface heating function, defined as the ratio of the time derivative of the mean annual temperature curve to the surface heat balance, is computed from the annual temperature range and heat balance data for the North American continent. An annual cycle of the surface heat balance is then reconstructed from the surface heating function and the annual temperature curve, and an annual cycle of evaporative plus turbulent heat loss is recomputed from the annual cycles of radiation balance and surface heat balance for the continent. The implications of these results for long range weather forecasting are discussed.

  3. A "Stratospheric Drain" over the Maritime Continent

    NASA Technical Reports Server (NTRS)

    Sherwood, Steve

    1999-01-01

    Evidence is presented from operational rawinsonde data surrounding the maritime continent that the net mass flux near the tropopause is downward over this region, contrary to the behavior of current numerical models. The air is descending year-round, despite mean upward motion below and above the descending layer. This sinking implies the existence of a significant energy-removing process, which is argued to be the injection of cold air by overshooting convective clouds. The mass, energy, and horizontal momentum budgets are examined in reaching these conclusions. The implied cooling effect of convective overshoots can be simulated with a simple, parcel-sorting convective mixing model. The findings contradict the common view that the mean flow enters the stratosphere in this strongly-convecting region, and have important implications for transport of water vapor and other gases into the stratosphere.

  4. Mid-frequency MTF compensation of optical sparse aperture system.

    PubMed

    Zhou, Chenghao; Wang, Zhile

    2018-03-19

    Optical sparse aperture (OSA) can greatly improve the spatial resolution of optical system. However, because of its aperture dispersion and sparse, its mid-frequency modulation transfer function (MTF) are significantly lower than that of a single aperture system. The main focus of this paper is on the mid-frequency MTF compensation of the optical sparse aperture system. Firstly, the principle of the mid-frequency MTF decreasing and missing of optical sparse aperture are analyzed. This paper takes the filling factor as a clue. The method of processing the mid-frequency MTF decreasing with large filling factor and method of compensation mid-frequency MTF with small filling factor are given respectively. For the MTF mid-frequency decreasing, the image spatial-variant restoration method is proposed to restore the mid-frequency information in the image; for the mid-frequency MTF missing, two images obtained by two system respectively are fused to compensate the mid-frequency information in optical sparse aperture image. The feasibility of the two method are analyzed in this paper. The numerical simulation of the system and algorithm of the two cases are presented using Zemax and Matlab. The results demonstrate that by these two methods the mid-frequency MTF of OSA system can be compensated effectively.

  5. Obesity and stress urinary incontinence in women: compromised continence mechanism or excess bladder pressure during cough?

    PubMed

    Swenson, Carolyn W; Kolenic, Giselle E; Trowbridge, Elisa R; Berger, Mitchell B; Lewicky-Gaupp, Christina; Margulies, Rebecca U; Morgan, Daniel M; Fenner, Dee E; DeLancey, John O

    2017-09-01

    We compared two hypotheses as to why obesity is associated with stress urinary incontinence (SUI): (1) obesity increases demand on the continence system (e.g. higher cough pressure) and (2) obesity compromises urethral function and urethrovaginal support. A secondary analysis was performed using data from a case-control study of SUI in women. Measurements of urethrovaginal support (POP-Q point Aa, urethral axis), urethral function (maximal urethral closure pressure, MUCP), and measures of continence system demand (intravesical pressures at rest and during maximal cough) were analyzed. Cases and controls were divided into three body mass index (BMI) groups: normal (18.5-24.9 kg/m 2 ); overweight (25.0-29.9 kg/m 2 ); and obese (≥30 kg/m 2 ). Logistic regression models where created to investigate variables related to SUI for each BMI group. Structural equation modeling was used to test the direct and indirect relationships among BMI, SUI, maximal cough pressure, MUCP, and POP-Q point Aa. The study included 108 continent controls and 103 women with SUI. MUCP was the factor most strongly associated with SUI in all BMI groups. Maximal cough pressure was significantly associated with SUI in obese women (OR 3.191, 95% CI 1.326, 7.683; p < 0.01), but not in normal weight or overweight women. Path model analysis showed a significant relationship between BMI and SUI through maximal cough pressure (indirect effect, p = 0.038), but not through MUCP (indirect effect, p = 0.243) or POP-Q point Aa (indirect effect, p = 0.410). Our results support the first hypothesis that obesity is associated with SUI because of increased intravesical pressure, which therefore increases demand on the continence mechanism.

  6. Nonlinear photothermal mid-infrared spectroscopy

    NASA Astrophysics Data System (ADS)

    Totachawattana, Atcha; Erramilli, Shyamsunder; Sander, Michelle Y.

    2016-10-01

    Mid-infrared photothermal spectroscopy is a pump-probe technique for label-free and non-destructive sample characterization by targeting intrinsic vibrational modes. In this method, the mid-infrared pump beam excites a temperature-induced change in the refractive index of the sample. This laser-induced change in the refractive index is measured by a near-infrared probe laser using lock-in detection. At increased pump powers, emerging nonlinear phenomena not previously demonstrated in other mid-infrared techniques are observed. Nonlinear study of a 6 μm-thick 4-Octyl-4'-Cyanobiphenyl (8CB) liquid crystal sample is conducted by targeting the C=C stretching band at 1606 cm-1. At high pump powers, nonlinear signal enhancement and multiple pitchfork bifurcations of the spectral features are observed. An explanation of the nonlinear peak splitting is provided by the formation of bubbles in the sample at high pump powers. The discontinuous refractive index across the bubble interface results in a decrease in the forward scatter of the probe beam. This effect can be recorded as a bifurcation of the absorption peak in the photothermal spectrum. These nonlinear effects are not present in direct measurements of the mid-infrared beam. Evolution of the nonlinear photothermal spectrum of 8CB liquid crystal with increasing pump power shows enhancement of the absorption peak at 1606 cm-1. Multiple pitchfork bifurcations and spectral narrowing of the photothermal spectrum are demonstrated. This novel nonlinear regime presents potential for improved spectral resolution as well as a new regime for sample characterization in mid-infrared photothermal spectroscopy.

  7. Novel rechargeable calcium phosphate nanoparticle-containing orthodontic cement

    PubMed Central

    Xie, Xian-Ju; Xing, Dan; Wang, Lin; Zhou, Han; Weir, Michael D; Bai, Yu-Xing; Xu, Hockin HK

    2017-01-01

    White spot lesions (WSLs), due to enamel demineralization, occur frequently in orthodontic treatment. We recently developed a novel rechargeable dental composite containing nanoparticles of amorphous calcium phosphate (NACP) with long-term calcium (Ca) and phosphate (P) ion release and caries-inhibiting capability. The objectives of this study were to develop the first NACP-rechargeable orthodontic cement and investigate the effects of recharge duration and frequency on the efficacy of ion re-release. The rechargeable cement consisted of pyromellitic glycerol dimethacrylate (PMGDM) and ethoxylated bisphenol A dimethacrylate (EBPADMA). NACP was mixed into the resin at 40% by mass. Specimens were tested for orthodontic bracket shear bond strength (SBS) to enamel, Ca and P ion initial release, recharge and re-release. The new orthodontic cement exhibited an SBS similar to commercial orthodontic cement without CaP release (P>0.1). Specimens after one recharge treatment (e.g., 1 min immersion in recharge solution repeating three times in one day, referred to as “1 min 3 times”) exhibited a substantial and continuous re-release of Ca and P ions for 14 days without further recharge. The ion re-release did not decrease with increasing the number of recharge/re-release cycles (P>0.1). The ion re-release concentrations at 14 days versus various recharge treatments were as follows: 1 min 3 times>3 min 2 times>1 min 2 times>6 min 1 time>3 min 1 time>1 min 1 time. In conclusion, although previous studies have shown that NACP nanocomposite remineralized tooth lesions and inhibited caries, the present study developed the first orthodontic cement with Ca and P ion recharge and long-term release capability. This NACP-rechargeable orthodontic cement is a promising therapy to inhibit enamel demineralization and WSLs around orthodontic brackets. PMID:27811847

  8. Novel rechargeable calcium phosphate nanoparticle-containing orthodontic cement.

    PubMed

    Xie, Xian-Ju; Xing, Dan; Wang, Lin; Zhou, Han; Weir, Michael D; Bai, Yu-Xing; Xu, Hockin Hk

    2017-03-01

    White spot lesions (WSLs), due to enamel demineralization, occur frequently in orthodontic treatment. We recently developed a novel rechargeable dental composite containing nanoparticles of amorphous calcium phosphate (NACP) with long-term calcium (Ca) and phosphate (P) ion release and caries-inhibiting capability. The objectives of this study were to develop the first NACP-rechargeable orthodontic cement and investigate the effects of recharge duration and frequency on the efficacy of ion re-release. The rechargeable cement consisted of pyromellitic glycerol dimethacrylate (PMGDM) and ethoxylated bisphenol A dimethacrylate (EBPADMA). NACP was mixed into the resin at 40% by mass. Specimens were tested for orthodontic bracket shear bond strength (SBS) to enamel, Ca and P ion initial release, recharge and re-release. The new orthodontic cement exhibited an SBS similar to commercial orthodontic cement without CaP release (P>0.1). Specimens after one recharge treatment (e.g., 1 min immersion in recharge solution repeating three times in one day, referred to as "1 min 3 times") exhibited a substantial and continuous re-release of Ca and P ions for 14 days without further recharge. The ion re-release did not decrease with increasing the number of recharge/re-release cycles (P>0.1). The ion re-release concentrations at 14 days versus various recharge treatments were as follows: 1 min 3 times>3 min 2 times>1 min 2 times>6 min 1 time>3 min 1 time>1 min 1 time. In conclusion, although previous studies have shown that NACP nanocomposite remineralized tooth lesions and inhibited caries, the present study developed the first orthodontic cement with Ca and P ion recharge and long-term release capability. This NACP-rechargeable orthodontic cement is a promising therapy to inhibit enamel demineralization and WSLs around orthodontic brackets.

  9. Analyzing the sources and nature of influence: how the Avahan program used evidence to influence HIV/AIDS prevention policy in India.

    PubMed

    Tran, Nhan T; Bennett, Sara C; Bishnu, Rituparna; Singh, Suneeta

    2013-04-17

    Major investments by development partners in low- and middle-income countries (LMICs) often seek to develop a supportive policy environment. There is limited knowledge about the mechanisms that development partners use to influence government policy, or which mechanisms are effective. This study assessed the influence of Avahan, a large HIV/AIDS prevention program in India supported by the Bill and Melinda Gates Foundation, on the development of HIV/AIDS policies in India, particularly the National AIDS Control Program III (NACP III). A retrospective assessment of the contributions of Avahan to the development of NACP III was conducted based upon document review and in-depth interviews with key informants, including Avahan staff and staff of implementing partners. This assessment was carried out within a framework centered on three domains: evidence considered by policy and decision-makers; the channel through which influence is exerted; and the target audience for influence. Respondents identified a number of respects in which Avahan influenced NACP III policy, notably, Avahan influenced perception of the feasibility of scaling up services (through a demonstration effect) and Avahan, along with others, helped ensure a strong focus on targeted interventions. Overall Avahan's influence was greatest during policy implementation. While the extent to which research evidence generated by Avahan influenced NACP III was limited, best practice evidence generated by Avahan, including the lessons learned from routine implementation and management, contributed significantly to NACP III. This was largely due to the credibility Avahan had established and strategic 'inside track' communications. While studies of knowledge translation typically focus primarily on scientific evidence, this study suggests that other forms of evidence, notably best practice evidence derived from program experience, and disseminated through personal communication, were particularly influential. The

  10. Possible tectonomagnetic effect observed from mid-1989, to mid-1990, in Long Valley Caldera, California

    USGS Publications Warehouse

    Mueller, R.J.; Johnston, M.J.S.; Langbein, J.O.

    1991-01-01

    Precise measurements of local magnetic fields have been obtained with a differentially connected array of three proton magnetometers in the Long Valley Caldera region since 1984. After correction for secular variation, it is apparent that an anomalous 2 nT decrease in the magnetic field occurred from mid-1989 to mid-1990 at the magnetometer located closed to the center of the resurgent dome inside the caldera. During this period a significant increase in geodetic strain rate of 8.5 ppm/a was observed on the two-color geodimeter network within the caldera from October, 1989, to mid-1990 and a dramatic increase in seismic activity occurred from December, 1989 to July, 1990. A simple dilatational point-source model with pressure increasing by 52 Mpa from October 1989 to August 1990 at a depth of about 7 km beneath the center of the resurgent dome can be fit to the strain data. Magnetic, seismic and geodetic data suggest that an episode of active magmatic intrusion occurred from late 1989 to mid-1990 at a depth of about 7-8 km beneath the resurgent dome within the caldera. -from Authors

  11. Geophysical investigations of the area between the Mid-Atlantic Ridge and the Barents Sea: From water to the lithosphere-asthenosphere system

    NASA Astrophysics Data System (ADS)

    Grad, Marek; Mjelde, Rolf; Krysiński, Lech; Czuba, Wojciech; Libak, Audun; Guterch, Aleksander

    2015-03-01

    As a part of the large international panel "IPY Plate Tectonics and Polar Gateways" within the "4th International Polar Year" framework, extensive geophysical studies were performed in the area of southern Svalbard, between the Mid-Atlantic Ridge and the Barents Sea. Seismic investigations were performed along three refraction and wide-angle reflection seismic lines. Integrated with gravity data the seismic data were used to determine the structure of the oceanic crust, the transition between continent and ocean (COT), and the continental structures down to the lithosphere-asthenosphere system (LAB). We demonstrate how modeling of multiple water waves can be used to determine the sound velocity in oceanic water along a seismic refraction profile. Our 2D seismic and density models documents 4-9 km thick oceanic crust formed at the Knipovich Ridge, a distinct and narrow continent-ocean transition (COT), the Caledonian suture zone between Laurentia and Barentsia, and 30-35 km thick continental crust beneath the Barents Sea. The COT west of southern Spitsbergen expresses significant excess density (more than 0.1 g/cm3 in average), which is characteristic for mafic/ultramafic and high-grade metamorphic rocks. The results of the gravity modeling show relatively weak correlation of the density with seismic velocity in the upper mantle, which suggests that the horizontal differences between oceanic and continental mantle are dominated by mineralogical changes, although a thermal effect is also present. The seismic velocity change with depth suggests lherzolite composition of the uppermost oceanic mantle, and dunite composition beneath the continental crust.

  12. The Tianlai 21cm intensity mapping experiment

    NASA Astrophysics Data System (ADS)

    Chen, Xuelei

    2015-08-01

    The Tianlai 21cm intensity mapping experiment is aimed at surveying the northern sky 21cm intensity at mid-redshifts, thus map out the neutral hydrogen distribution. The experiment is named "Tianlai" which means "heavenly sound" in classic Chinese, because its ultimate goal is to use the baryon acoustic oscillation (BAO) feature in the correlation function or power spectrum of large scale structure to constrain the cosmic expansion rate, and determine the nature of dark energy.The pathfinder experiment consists three cylinder reflectors of 15m wide x 40m long, and 16 dishes of 6 meter aperture, for testing the basic principle and key technologies. A radio-quiet site in Hongliuxia, Xinjiang of north-west China is selected, currently the facilities are under construction, and the prototype is expected to start commissioning later this year. The experiment is run by NAOC, with members from France, USA and Canada.

  13. Clinical value of colonic irrigation in patients with continence disturbances.

    PubMed

    Briel, J W; Schouten, W R; Vlot, E A; Smits, S; van Kessel, I

    1997-07-01

    Continence disturbances, especially fecal soiling, are difficult to treat. Irrigation of the distal part of the large bowel might be considered as a nonsurgical alternative for patients with impaired continence. This study is aimed at evaluating the clinical value of colonic irrigation. Thirty-two patients (16 females; median age, 47 (range, 23-72) years) were offered colonic irrigation on an ambulatory basis. Sixteen patients suffered from fecal soiling (Group I), whereas the other 16 patients were treated for fecal incontinence (Group II). Patients were instructed by enterostomal therapists how to use a conventional colostomy irrigation set to obtain sufficient irrigation of the distal part of their large bowel. Patients with continence disturbances during the daytime were instructed to introduce 500 to 1,000 ml of warm (38 degrees C) water within 5 to 10 minutes after they passed their first stool. In addition, they were advised to wait until the urge to defecate was felt. Patients with soiling during overnight sleep were advised to irrigate during the evening. To determine clinical outcome, a detailed questionnaire was used. Median duration of follow-up was 18 months. Ten patients discontinued irrigation within the first month of treatment. Symptoms resolved completely in two patients. They believed that there was no need to continue treatment any longer. Irrigation had no effect in two patients. Despite the fact that symptoms resolved, six patients discontinued treatment because they experienced pain (n = 2) or they considered the irrigation to be too time-consuming (n = 4). Twenty-two patients are still performing irrigations. Most patients irrigated the colon in the morning after the first stool was passed. Time needed for washout varied between 10 and 90 minutes. Frequency of irrigations varied from two times per day to two times per week. In Group I, irrigation was found to be beneficial in 92 percent of patients, whereas 60 percent of patients in Group II

  14. Mid-Career PhD Physicists: Academia & Beyond

    NASA Astrophysics Data System (ADS)

    White, Susan

    2017-01-01

    What jobs do mid-career PhD physicists hold? In a first-ever study, we collected data in 2011 from over 1,500 physics PhD recipients from the classes of 1996, 1997, 2000, and 2001. About 45% of the physics PhD recipients in these classes immediately took jobs that were not temporary, and over 40% accepted postdocs. How does taking a postdoc affect mid-career employment? What is the relationship between first job (after any postdocs) and mid-career employment? How do physicists' actual jobs compare with what they thought they would be doing when they graduated? Using our initial employment and mid-career data, I will answer these questions and more.

  15. Broadband mid-infrared and THz chemical detection with quantum cascade laser multi-heterodyne spectrometers (Conference Presentation)

    NASA Astrophysics Data System (ADS)

    Westberg, Jonas; Sterczewski, Lukasz A.; Patrick, Link; Wysocki, Gerard

    2017-05-01

    Majority of chemical species of interest in security and safety applications (e.g. explosives) have complex molecular structures that produce unresolved rotational-vibrational spectroscopic signatures in the mid-infrared. This requires spectroscopic techniques that can provide broadband coverage in the mid-IR region to target broadband absorbers and high resolution to address small molecules that exhibit well-resolved spectral lines. On the other hand, many broadband mid-IR absorbers exhibit well-resolved rotational components in the THz spectral region. Thus, development of spectroscopic sensing technologies that can address both spectral regions is of great importance. Here we demonstrate recent progress towards broadband high-resolution spectroscopic sensing applications with Fabry-Perot quantum cascade lasers (QCLs) and frequency combs using multi-heterodyne spectroscopy (MHS) techniques. In this paper, we will present spectroscopic sensing of large and small molecules in the mid-IR region using QCLs operating at 8.5µm. An example high-resolution, broadband MHS of ammonia (small molecule) and isobutane (broadband absorber) at atmospheric pressure in the 1165-1190 cm^-1 range will be discussed. We have developed a balanced MHS system for mitigation of the laser intensity fluctuations. Absorption spectroscopy as well as dispersion spectroscopy with minimum fractional absorption down to 10^-4/Hz1/2 and fast spectral acquisition capabilities down to 10 µs/spectrum range will be demonstrated. In order to mitigate the shortcomings of the limited chemical selectivity in the mid-IR, THz QCL based spectrometer is currently under development to provide spectral de-congestion and thus significantly improve chemical identification. Preliminary characterization of the performance of THZ QCL combs for the THz QCL-MHS will be presented.

  16. Archean komatiite volcanism controlled by the evolution of early continents.

    PubMed

    Mole, David R; Fiorentini, Marco L; Thebaud, Nicolas; Cassidy, Kevin F; McCuaig, T Campbell; Kirkland, Christopher L; Romano, Sandra S; Doublier, Michael P; Belousova, Elena A; Barnes, Stephen J; Miller, John

    2014-07-15

    The generation and evolution of Earth's continental crust has played a fundamental role in the development of the planet. Its formation modified the composition of the mantle, contributed to the establishment of the atmosphere, and led to the creation of ecological niches important for early life. Here we show that in the Archean, the formation and stabilization of continents also controlled the location, geochemistry, and volcanology of the hottest preserved lavas on Earth: komatiites. These magmas typically represent 50-30% partial melting of the mantle and subsequently record important information on the thermal and chemical evolution of the Archean-Proterozoic Earth. As a result, it is vital to constrain and understand the processes that govern their localization and emplacement. Here, we combined Lu-Hf isotopes and U-Pb geochronology to map the four-dimensional evolution of the Yilgarn Craton, Western Australia, and reveal the progressive development of an Archean microcontinent. Our results show that in the early Earth, relatively small crustal blocks, analogous to modern microplates, progressively amalgamated to form larger continental masses, and eventually the first cratons. This cratonization process drove the hottest and most voluminous komatiite eruptions to the edge of established continental blocks. The dynamic evolution of the early continents thus directly influenced the addition of deep mantle material to the Archean crust, oceans, and atmosphere, while also providing a fundamental control on the distribution of major magmatic ore deposits.

  17. Archean komatiite volcanism controlled by the evolution of early continents

    PubMed Central

    Mole, David R.; Fiorentini, Marco L.; Thebaud, Nicolas; Cassidy, Kevin F.; McCuaig, T. Campbell; Kirkland, Christopher L.; Romano, Sandra S.; Doublier, Michael P.; Belousova, Elena A.; Barnes, Stephen J.; Miller, John

    2014-01-01

    The generation and evolution of Earth’s continental crust has played a fundamental role in the development of the planet. Its formation modified the composition of the mantle, contributed to the establishment of the atmosphere, and led to the creation of ecological niches important for early life. Here we show that in the Archean, the formation and stabilization of continents also controlled the location, geochemistry, and volcanology of the hottest preserved lavas on Earth: komatiites. These magmas typically represent 50–30% partial melting of the mantle and subsequently record important information on the thermal and chemical evolution of the Archean–Proterozoic Earth. As a result, it is vital to constrain and understand the processes that govern their localization and emplacement. Here, we combined Lu-Hf isotopes and U-Pb geochronology to map the four-dimensional evolution of the Yilgarn Craton, Western Australia, and reveal the progressive development of an Archean microcontinent. Our results show that in the early Earth, relatively small crustal blocks, analogous to modern microplates, progressively amalgamated to form larger continental masses, and eventually the first cratons. This cratonization process drove the hottest and most voluminous komatiite eruptions to the edge of established continental blocks. The dynamic evolution of the early continents thus directly influenced the addition of deep mantle material to the Archean crust, oceans, and atmosphere, while also providing a fundamental control on the distribution of major magmatic ore deposits. PMID:24958873

  18. Urinary continence in women during centrifuge exposure to high +Gz.

    PubMed

    Benjamin, C R; Hearon, C M

    2000-02-01

    One earlier study and anecdotal evidence suggest a possible association between exposure to high +Gz forces and urinary incontinence in women. High +Gz could possibly contributes to the prolapse of the bladder neck, moving it into a position which decreases the leak point pressure resulting in urinary incontinence. We tested the hypothesis that increased urinary incontinence is associated with high +Gz. 25 females were exposed to a high +Gz profile. Following the exposure they were asked to answer a questionnaire grading their urinary continence under high +Gz, and to provide a baseline grading of their urinary continence at +1.0 Gz and under increased abdominal stress at +1.0 Gz. Demographic data included parity and previous urogenital surgery. Graded responses were dichotomized and data was analyzed using Fischer's Exact Test for 2x2 tables with significance set at alpha = 0.05. At high +Gz no significant association was found between reported urine incontinence and a history of urogenital surgery or parity. Only one of twenty-five subjects had any symptoms at high +Gz despite the fact that five had a predisposition. As expected, at +1.0 Gz and under increased abdominal stress at +1.0 Gz a significant association was found between reported urine incontinence and a history of urogenital surgery, while no significant association was found for parity. In this simple first look there was no increase in urinary incontinence at high +Gz even among those who reported a predisposition.

  19. Using a handbook to improve nurses' continence care.

    PubMed

    Williams, K; Roe, B; Sindhu, F

    Nursing care should be based on sound research evidence with demonstrated clinical effectiveness. Dissemination of this research evidence is, therefore, of paramount importance. A study using focus groups was undertaken during 1993-1994 to evaluate the dissemination of a clinical handbook for continence care to qualified nurses, in relation to reported nursing practice in care of the elderly wards/units in one health authority. A total of 124 nurses participated in the study and 98 variables were included. Improvements were recorded in nurses' responses between the pre-test and post-test for 84 (86 per cent) variables in the experimental group and 58 (59 per cent) in the control group. This demonstrates the positive value of the clinical handbook as a method of disseminating research evidence.

  20. Plants of the American continent with antiulcer activity.

    PubMed

    Falcão, H S; Mariath, I R; Diniz, M F F M; Batista, L M; Barbosa-Filho, J M

    2008-01-01

    Peptic ulcer is a chronic and appalling disease. Today, it is dominant among the diseases that affect the world's population. The principal factors causing this disease are inadequate dietetic habits, prolonged use of non-steroidal anti-inflammatory drugs, stress and infection by Helicobacter pylori, in addition to other factors of genetic origin. The present work is a literature survey of plant extracts from the American continent that have been reported to show antiulcer activity. This review refers to 58 plants with their families, parts used, type of extract used, model bioassays and their activity. This work intends to aid the researchers in the study of natural products appropriate to the treatment of stomach and intestinal diseases, in general, and peptic ulcer in particular.

  1. Rotational inertia of continents: A proposed link between polar wandering and plate tectonics

    USGS Publications Warehouse

    Kane, M.F.

    1972-01-01

    A mechanism is proposed whereby displacement between continents and the earth's pole of rotation (polar wandering) gives rise to latitudinal transport of continental plates (continental drift) because of their relatively greater rotational inertia. When extended to short-term polar wobble, the hypothesis predicts an energy change nearly equivalent to the seismic energy rate.

  2. Late recurrent urothelial carcinoma in the Studer neobladder: conversion to continent reservoir

    PubMed Central

    Kotb, AF; Alkosiry, M; AbdElkawy, N; Atta, MA

    2012-01-01

    Bladder cancer represents a considerable issue in Egypt and the Middle East. Radical cystectomy and orthotopic neobladder represent the standard of care for managing cases with invasive bladder tumour. There are few cases reported in the literature considering the urothelial recurrence in the urethra, connected to neobladder. We are presenting a rare case of a young female patient, with an aggressive urothelial tumour, recurring 13-year post-radical cystectomy, and the Studer neobladder. Our case was managed by urethrectomy and conversion of the neobladder into continent reservoir, with good short-term oncological and functional outcomes. We can conclude that bladder cancer cases should be followed thoroughly throughout their life. Follow-up urethroscopy and cytology should be done for all cases of post-radical cystectomy, regardless of patients’ symptoms. Key message Late urothelial recurrence of post-radical cystectomy is possible and, in our case, happened 13 years following surgery. The Studer neobladder can be safely converted into continent reservoir, allowing good functional outcomes. Also, recurrence in the Studer neobladder can be safely managed, allowing good oncological outcomes, without the need for any ureteroileal interventions. PMID:22973413

  3. Impact of high-latitude energy input on the mid- and low-latitude ionosphere and thermosphere

    NASA Astrophysics Data System (ADS)

    Lu, G.; Sheng, C.

    2017-12-01

    High-latitude energy input has a profound impact on the ionosphere and thermosphere especially during geomagnetic storms. Intense auroral particle precipitation ionizes neutral gases and modifies ionospheric conductivity; collisions between neutrals and fast-moving ions accelerate the neutral winds and produce Joule frictional heating; and the excess Joule and particle heating causes atmospheric upwelling and changes neutral composition due to the rising of the heavier, molecular-rich air. In addition, impulsive Joule heating launches large-scale gravity waves that propagate equatorward toward middle and low latitudes and even into the opposite hemisphere, altering the mean global circulation of the thermosphere. Furthermore, high-latitude electric field can also directly penetrate to lower latitudes under rapidly changing external conditions, causing prompt ionospheric variations in the mid- and low-latitude regions. To study the effects of high-latitude energy input, we apply the different convection and auroral precipitation patterns based on both empirical models and the AMIE outputs. We investigate how the mid- and low-latitude regions respond to the different specifications of high-latitude energy input. The main purpose of the study is to delineate the various dynamical, electrodynamical, and chemical processes and to determine their relative importance in the resulting ionospheric and thermospheric properties at mid and low latitudes.

  4. Continent or incontinent? That is the question.

    PubMed

    Taunton, Roma Lee; Swagerty, Daniel L; Lasseter, Joyce A; Lee, Robert H

    2005-09-01

    A qualitative, emergent, case study design guided the description of care provided to nursing home residents with urinary incontinence in three Midwestern nursing facilities. Participants included 17 residents and 16 family members or friends of the respective residents. Staff and managers involved in the planning and delivery of care to the participating residents also were included. The three facilities represented variation in size, location, ownership, and Medicare certification. Data were collected via observation, resident record audit, and semi-structured interview. Definitions of incontinence varied among staff. A collectively held expectation that residents would be toileted every 2 hours was not met. Maintaining skin integrity was the primary motivation for keeping residents clean and dry. Medical directors viewed incontinence as a nursing problem. Staff described situations in which incontinence was improved for specific residents, but there was little evidence of formal programs to maintain continence or improve incontinence.

  5. Synoptic-scale circulation patterns during summer derived from tree rings in mid-latitude Asia

    NASA Astrophysics Data System (ADS)

    Seim, Andrea; Schultz, Johannes A.; Leland, Caroline; Davi, Nicole; Byambasuren, Oyunsanaa; Liang, Eryuan; Wang, Xiaochun; Beck, Christoph; Linderholm, Hans W.; Pederson, Neil

    2017-09-01

    Understanding past and recent climate and atmospheric circulation variability is vital for regions that are affected by climate extremes. In mid-latitude Asia, however, the synoptic climatology is complex and not yet fully understood. The aim of this study was to investigate dominant synoptic-scale circulation patterns during the summer season using a multi-species tree-ring width (TRW) network comprising 78 sites from mid-latitude Asia. For each TRW chronology, we calculated an atmospheric circulation tree-ring index (ACTI), based on 1000 hPa geopotential height data, to directly link tree growth to 13 summertime weather types and their associated local climate conditions for the period 1871-1993. Using the ACTI, three groups of similarly responding tree-ring sites can be associated with distinct large-scale atmospheric circulation patterns: 1. growth of drought sensitive trees is positively affected by a cyclone over northern Russia; 2. temperature sensitive trees show positive associations to a cyclone over northwestern Russia and an anticyclone over Mongolia; 3. trees at two high elevation sites show positive relations to a zonal cyclone extending from mid-latitude Eurasia to the West Pacific. The identified synoptic-scale circulation patterns showed spatiotemporal variability in their intensity and position, causing temporally varying climate conditions in mid-latitude Asia. Our results highlight that for regions with less pronounced atmospheric action centers during summer such as the occurrence of large-scale cyclones and anticyclones, synoptic-scale circulation patterns can be extracted and linked to the Northern Hemisphere circulation system. Thus, we provide a new and solid envelope for climate studies covering the past to the future.

  6. 12 CFR 252.145 - Mid-cycle stress test.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 12 Banks and Banking 4 2013-01-01 2013-01-01 false Mid-cycle stress test. 252.145 Section 252.145... (CONTINUED) ENHANCED PRUDENTIAL STANDARDS (REGULATION YY) Company-Run Stress Test Requirements for Covered Companies § 252.145 Mid-cycle stress test. (a) Mid-cycle stress test requirement. In addition to the stress...

  7. 12 CFR 252.145 - Mid-cycle stress test.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 12 Banks and Banking 4 2014-01-01 2014-01-01 false Mid-cycle stress test. 252.145 Section 252.145... (CONTINUED) ENHANCED PRUDENTIAL STANDARDS (REGULATION YY) Company-Run Stress Test Requirements for Covered Companies § 252.145 Mid-cycle stress test. (a) Mid-cycle stress test requirement. In addition to the stress...

  8. Assessing and evaluating urban VOC emissions in mid-latitude megacities from intensive observations in Paris and Los Angeles

    NASA Astrophysics Data System (ADS)

    Borbon, A.; Gilman, J. B.; Kuster, W. C.; McKeen, S. A.; Holloway, J. S.; Gros, V.; Gaimoz, C.; Beekmann, M.; De Gouw, J. A.

    2011-12-01

    Volatile Organic Compounds (VOC) affect urban air quality and regional climate change by contributing to ozone formation and the build-up of Secondary Organic Aerosols (SOA). Quantification of VOC emissions is a first critical step to predict VOC environmental impacts and to design effective abatement strategies. Indeed, the quality of ozone and SOA forecasts strongly depends on an accurate knowledge of the primary VOC emissions. However, commonly used bottom-up approaches are highly uncertain due to source multiplicity (combustion processes, storage and distribution of fossil fuels, solvent use, etc.) because of numerous controlling factors (driving conditions, fuel type, temperature, radiation, etc.), and their great variability in time and space. Field observations of VOC and other trace gases can provide valuable top-down constraints to evaluate VOC emission inventories at urban scales. In addition, the implementation of emission reduction measures raises the question of the increasing importance of VOC sources other than traffic. Here, we will evaluate VOC emissions of two mid-latitude megacities in the Northern Hemisphere: the Greater Paris area (Europe) and Los Angeles (USA). In 2009 and 2010, three intensive field campaigns took place in Paris and Los Angeles in the framework of the MEGAPOLI (EU FP7) and CalNex-2010 projects, respectively. Very detailed measurements of aerosol composition and properties, and their gaseous VOC precursors were carried out at ground-based sites (urban center and suburban) and on various mobile platforms. This contribution uses a comprehensive suite of VOC measurements collected by GC-MS/FID techniques at ground-based sites in both cities by a source-receptor methodology. First, emission ratios were estimated from the observations (uncertainty of ± 20%) and compared regarding regional characteristics and European vs. Californian control policies. Then, determined emission ratios were used to assess the accuracy of up

  9. Mid-infrared-to-mid-ultraviolet supercontinuum enhanced by third-to-fifteenth odd harmonics.

    PubMed

    Mitrofanov, A V; Voronin, A A; Mitryukovskiy, S I; Sidorov-Biryukov, D A; Pugžlys, A; Andriukaitis, G; Flöry, T; Stepanov, E A; Fedotov, A B; Baltuška, A; Zheltikov, A M

    2015-05-01

    A high-energy supercontinuum spanning 4.7 octaves, from 250 to 6500 nm, is generated using a 0.3-TW, 3.9-μm output of a mid-infrared optical parametric chirped-pulse amplifier as a driver inducing a laser filament in the air. The high-frequency wing of the supercontinuum spectrum is enhanced by odd-order optical harmonics of the mid-infrared driver. Optical harmonics up to the 15th order are observed in supercontinuum spectra as overlapping, yet well-resolved peaks broadened, as verified by numerical modeling, due to spatially nonuniform ionization-induced blue shift.

  10. Ultrasound Thickness of Bladder Wall in Continent and Incontinent Women and Its Correlation with Cystometry

    PubMed Central

    Otsuki, Edney Norio; Oliveira, Emerson; Sartori, Marair Gracio Ferreira; Girão, Manoel João Batista Castelo; Jármy-Di Bella, Zsuzsanna Ilona Katalin

    2014-01-01

    Objective. To compare bladder wall thickness in two kinds of urinary incontinent women—stress urinary incontinence (SUI) and overactive bladder (OAB) with urodynamic detrusor overactivity (DO), and to compare them with continent patients by ultrasound, also, correlate with cystometric results in incontinent women. Methods. 91 women were divided into the following groups: continent (n = 31), SUI (n = 30), and DO (n = 30) groups after clinical evaluation and urodynamic test (only in incontinent women). Transvaginal ultrasound was performed to the bladder wall thickness (BWT) measurement. The mean of BWT was calculated and data were analyzed with ANOVA and Turkey's multiple comparison tests. Pearson's correlation coefficient (r) was used to compare two variables. Receiver operating characteristic (ROC) curve was performed to study BWT as a diagnostic parameter. Results. BWT in DO group was significantly higher than that in the other groups (P < 0.005). A moderate positive correlation was found between BWT and maximum bladder pressure during involuntary bladder contraction. There was no difference in BWT between SUI and continent groups. DO group had lower first desire to void and cystometric capacity. Maximum bladder pressure at detrusor contraction had a moderate positive correlation with BWT. The ROC revealed an area under the curve of 0.962 (95% CI, 0.90–1.01). Conclusions. DO patients have increased bladder wall thickness, lower first desire to void, and lower cystometric capacity. There was a moderate correlation between BWT and maximum bladder pressure during involuntary bladder contraction. PMID:25538959

  11. Factors affecting choice between ureterostomy, ileal conduit and continent reservoir after radical cystectomy: Japanese series.

    PubMed

    Sugihara, Toru; Yasunaga, Hideo; Horiguchi, Hiromasa; Fujimura, Tetsuya; Fushimi, Kiyohide; Yu, Changhong; Kattan, Michael W; Homma, Yukio

    2014-12-01

    Little is known about the disparity of choices between three urinary diversions after radical cystectomy, focusing on patient and institutional factors. We identified urothelial carcinoma patients who received radical cystectomy with cutaneous ureterostomy, ileal conduit or continent reservoir using the Japanese Diagnosis Procedure Combination database from 2007 to 2012. Data comprised age, sex, comorbidities (converted into the Charlson index), TNM classification (converted into oncological stage), hospitals' academic status, hospital volume, bed volume and geographical region. Multivariate ordinal logistic regression analyses fitted with the proportional odds model were performed to analyze factors affecting urinary diversion choices. For dependent variables, the three diversions were converted into an ordinal variable in order of complexity: cutaneous ureterostomy (reference), ileal conduit and continent reservoir. Geographical variations were also examined by multivariate logistic regression models. A total of 4790 patients (1131 cutaneous ureterostomies [23.6 %], 2970 ileal conduits [62.0 %] and 689 continent reservoirs [14.4 %]) were included. Ordinal logistic regression analyses showed that male sex, lower age, lower Charlson index, early tumor stage, higher hospital volume (≥3.4 cases/year) and larger bed volume (≥450 beds) were significantly associated with the preference of more complex urinary diversion. Significant geographical disparity was also found. Good patient condition and early oncological status, as well as institutional factors, including high hospital volume, large bed volume and specific geographical regions, are independently related to the likelihood of choosing complex diversions. Recognizing this disparity would help reinforce the need for clinical practice uniformity.

  12. Polarization effects in above-threshold ionization with a mid-infrared strong laser field

    NASA Astrophysics Data System (ADS)

    Kang, Hui-Peng; Xu, Song-Po; Wang, Yan-Lan; Yu, Shao-Gang; Zhao, Xiao-Yun; Hao, Xiao-Lei; Lai, Xuan-Yang; Pfeifer, Thomas; Liu, Xiao-Jun; Chen, Jing; Cheng, Ya; Xu, Zhi-Zhan

    2018-05-01

    Using a semiclassical approach, we theoretically study the above-threshold ionization of magnesium by intense, mid-infrared laser pulses. The formation of low-energy structures in the photoelectron spectrum is found to be enhanced by comparing with a calculation based on the single-active electron approximation. By performing electron trajectory and recollision-time distribution analysis, we demonstrate that this phenomenon is due to the laser-induced ionic core polarization effects on the recolliding electrons. We also show that the polarization effects should be experimentally detectable. Our finding provides new insight into ultrafast control of strong-field photoionization and imaging of polar molecules.

  13. Mid-America Trades with the World.

    ERIC Educational Resources Information Center

    Social Studies Development Center, Bloomington, IN.

    The booklet is designed to be used as a teaching resource for junior high or secondary classes studying global affairs and interdependence. It describes the transnational exchange of farm products and manufactured goods between mid-America and foreign countries. Mid-America is made up of the 12 Great Lakes and Plains states, which include prime…

  14. Mid-trimester induced abortion: a review.

    PubMed

    Lalitkumar, S; Bygdeman, M; Gemzell-Danielsson, K

    2007-01-01

    Mid-trimester abortion constitutes 10-15% of all induced abortion. The aim of this article is to provide a review of the current literature of mid-trimester methods of abortion with respect to efficacy, side effects and acceptability. There have been continuing efforts to improve the abortion technology in terms of effectiveness, technical ease of performance, acceptability and reduction of side effects and complications. During the last decade, medical methods for mid-trimester induced abortion have shown a considerable development and have become safe and more accessible. The combination of mifepristone and misoprostol is now an established and highly effective method for termination of pregnancy (TOP). Advantages and disadvantages of medical versus surgical methods are discussed. Randomized studies are lacking, and more studies on pain treatment and the safety of any method used in patients with a previous uterine scar are debated, and data are scarce. Pain management in abortion requires special attention. This review highlights the need for randomized studies to set guidelines for mid-trimester abortion methods in terms of safety and acceptability as well as for better analgesic regimens.

  15. Longitudinal Study of Intestinal Symptoms and Fecal Continence in Patients With Conformal Radiotherapy for Prostate Cancer

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Geinitz, Hans, E-mail: hans.geinitz@lrz.tu-muenchen.d; Thamm, Reinhard; Keller, Monika

    2011-04-01

    Purpose: To prospectively assess the intestinal symptoms and fecal continence in patients who had undergone conformal radiotherapy (CRT) for prostate cancer. Methods and Materials: A total of 78 men who had undergone definitive CRT for prostate cancer were evaluated. The patients were assessed before, during (treatment Weeks 4 and 6), and 2, 12, and 24 months after CRT completion. The intestinal symptoms and fecal continence were evaluated with comprehensive standardized questionnaires. Results: The intestinal symptoms were mostly intermittent, with only a small minority of patients affected daily. Defecation pain, fecal urge, and rectal mucous discharge increased significantly during therapy. Defecationmore » pain and rectal mucous discharge had returned to baseline levels within 8 weeks and 1 year after CRT, respectively. However, fecal urge remained significantly elevated for {<=}1 year and then returned toward the pretreatment values. The prevalence of rectal bleeding was significantly elevated 2 years after CRT. Fecal continence deteriorated during CRT and remained impaired at 1 year after treatment. Incontinence was mostly minor, occurring less than once per week and predominantly affecting incontinence for gas. Conclusion: Intestinal symptoms and fecal incontinence increased during prostate CRT. Except for rectal bleeding, the intestinal symptoms, including fecal incontinence, returned to baseline levels within 1-2 years after CRT. Thus, the rate of long-term late radiation-related intestinal toxicity was low.« less

  16. A Geodynamic model for melt generation and evolution of the Mid-Continental Rift

    NASA Astrophysics Data System (ADS)

    Gunawardana, P. M.; Moucha, R.; Rooney, T. O.; Stein, S.; Stein, C. A.; Hansen, M.

    2017-12-01

    The Mid-Continent Rift System (MCRS) is a 3000-km long failed rift system which formed within the Precambrian continent of Laurentia and nearly split North America apart about 1.1 billion years ago. The MCRS can also be classified as a Large Igneous Province (LIP) made up of two distinct magmatic phases (Stein et al., 2015). The first large scale magmatism is characterized by a large volume of flood basalt that filled a fault controlled basin. The second post-rift phase consists of volcanics and sediment that were deposited in a thermally subsiding basin after faulting ended. This flood basalt filled rift geometry is a special characteristic of the MCRS which is not observed in other presently active or ancient rifts. Hence the MCRS's unusual nature likely reflects the combined effects of rifting and a mantle plume. We investigate this hypothesis with a geodynamic model by fully exploring the parameter space for a range of mantle potential and plume excess temperatures as well as different extension scenarios and lithospheric/plume structure. We quantify the rate and amount of melt generated and compare these with inferred volume and history of magmatic activity. Our model suggests that for an initially thin 100 km continental lithosphere and high mantle potential temperatures above 1453 oC, a plume is not required to generate the inferred volume of flood basalt as long as the lithosphere is thinned rapidly (> 3cm/yr). We note that in this scenario, majority of the melt generation continues for a few million years after the rifting ends. However, for present-day mantle potential temperatures ( 1343 oC) a mantle plume is required with an excess of temperature > 100 oC to generate the required volume of flood basalt. Furthermore, if the initial continental lithosphere thickness is greater than 100 km, the required plume excess temperature to generate enough melt, must be > 200 oC for the range of mantle potential temperatures we explored. References Stein, C.A., Kley

  17. Episode of intense chemical weathering during the termination of the 635 Ma Marinoan glaciation.

    PubMed

    Huang, Kang-Jun; Teng, Fang-Zhen; Shen, Bing; Xiao, Shuhai; Lang, Xianguo; Ma, Hao-Ran; Fu, Yong; Peng, Yongbo

    2016-12-27

    Cryogenian (∼720-635 Ma) global glaciations (the snowball Earth) represent the most extreme ice ages in Earth's history. The termination of these snowball Earth glaciations is marked by the global precipitation of cap carbonates, which are interpreted to have been driven by intense chemical weathering on continents. However, direct geochemical evidence for the intense chemical weathering in the aftermath of snowball glaciations is lacking. Here, we report Mg isotopic data from the terminal Cryogenian or Marinoan-age Nantuo Formation and the overlying cap carbonate of the basal Doushantuo Formation in South China. A positive excursion of extremely high δ 26 Mg values (+0.56 to +0.95)-indicative of an episode of intense chemical weathering-occurs in the top Nantuo Formation, whereas the siliciclastic component of the overlying Doushantuo cap carbonate has significantly lower δ 26 Mg values (<+0.40), suggesting moderate to low intensity of chemical weathering during cap carbonate deposition. These observations suggest that cap carbonate deposition postdates the climax of chemical weathering, probably because of the suppression of carbonate precipitation in an acidified ocean when atmospheric CO 2 concentration was high. Cap carbonate deposition did not occur until chemical weathering had consumed substantial amounts of atmospheric CO 2 and accumulated high levels of oceanic alkalinity. Our finding confirms intense chemical weathering at the onset of deglaciation but indicates that the maximum weathering predated cap carbonate deposition.

  18. Tracing Males From Different Continents by Genotyping JC Polyomavirus in DNA From Semen Samples.

    PubMed

    Rotondo, John Charles; Candian, Tommaso; Selvatici, Rita; Mazzoni, Elisa; Bonaccorsi, Gloria; Greco, Pantaleo; Tognon, Mauro; Martini, Fernanda

    2017-05-01

    The human JC polyomavirus (JCPyV) is an ubiquitous viral agent infecting approximately 60% of humans. Recently, JCPyV sequences have been detected in semen samples. The aim of this investigation was to test whether semen JCPyV genotyping can be employed to trace the origin continent of males. Semen DNA samples (n = 170) from males of different Continents were investigated by PCR for the polymorphic JCPyV viral capsid protein 1 (VP1) sequences, followed by DNA sequencing. JCPyV sequences were detected with an overall prevalence of 27.6% (47/170). DNA sequencing revealed that European males carried JCPyV types 1A (71.4%), 4 (11.4%), 2B (2.9%), 2D1 (2.9%), and 3A (2.9%). Asians JCPyV type 2D1 (66.7%) and Africans JCPyV types 3A (33.3%) and 1A (33.3%). In 10.6% of males, two different JCPyV genotypes were detected, suggesting that the second JCPyV genotype was acquired in the destination country. This study indicates that the majority of semen samples found to be JCPyV-positive, were infected with the JCPyV genotype found in the geographic area of male origin. Therefore, semen JCPyV genotyping could be employed to trace the origin continent of males. Our findings could be applied to forensic investigations, in case of for instance sexual crimes. Indeed, JCPyV genotyping should enable investigators to make additional detailed profiling of the offender. J. Cell. Physiol. 232: 982-985, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  19. Earth's first stable continents did not form by subduction.

    PubMed

    Johnson, Tim E; Brown, Michael; Gardiner, Nicholas J; Kirkland, Christopher L; Smithies, R Hugh

    2017-03-09

    The geodynamic environment in which Earth's first continents formed and were stabilized remains controversial. Most exposed continental crust that can be dated back to the Archaean eon (4 billion to 2.5 billion years ago) comprises tonalite-trondhjemite-granodiorite rocks (TTGs) that were formed through partial melting of hydrated low-magnesium basaltic rocks; notably, these TTGs have 'arc-like' signatures of trace elements and thus resemble the continental crust produced in modern subduction settings. In the East Pilbara Terrane, Western Australia, low-magnesium basalts of the Coucal Formation at the base of the Pilbara Supergroup have trace-element compositions that are consistent with these being source rocks for TTGs. These basalts may be the remnants of a thick (more than 35 kilometres thick), ancient (more than 3.5 billion years old) basaltic crust that is predicted to have existed if Archaean mantle temperatures were much hotter than today's. Here, using phase equilibria modelling of the Coucal basalts, we confirm their suitability as TTG 'parents', and suggest that TTGs were produced by around 20 per cent to 30 per cent melting of the Coucal basalts along high geothermal gradients (of more than 700 degrees Celsius per gigapascal). We also analyse the trace-element composition of the Coucal basalts, and propose that these rocks were themselves derived from an earlier generation of high-magnesium basaltic rocks, suggesting that the arc-like signature in Archaean TTGs was inherited from an ancestral source lineage. This protracted, multistage process for the production and stabilization of the first continents-coupled with the high geothermal gradients-is incompatible with modern-style plate tectonics, and favours instead the formation of TTGs near the base of thick, plateau-like basaltic crust. Thus subduction was not required to produce TTGs in the early Archaean eon.

  20. Addressing incontinence for people with dementia living at home: a documentary analysis of local English community nursing service continence policies and clinical guidance.

    PubMed

    Drennan, Vari M; Norrie, Caroline; Cole, Laura; Donovan, Sheila

    2013-02-01

    To establish whether the problems and issues experienced by people with dementia living at home and their carers were addressed in the clinical guidance for continence management for community nursing services in England. Internationally, the numbers of people with dementia are rising. Managing incontinence is a significant issue as the presence of incontinence is one of the triggers for people with dementia to move their residence to a care home. People with dementia living at home and their family carers report difficulties in accessing knowledgeable professionals and acceptable continence products. A review by documentary analysis of clinical policies and guidance from a sample of community nursing services in all Strategic Health Authority regions of England. A sample of clinical policy and guidance documents for continence assessment and management from up to four community nursing services in each of the ten Strategic Health Authority regions in England was sought. Documentary analysis was undertaken on the relevance of the documents identified for people with dementia living at home. Ninety-eight documents from 38 local community nursing services spread across ten Strategic Health Authority areas were obtained and analysed. Only in the documents of three services were nurses offered detailed guidance about the management of incontinence for people with dementia at home. In the documentation of only one service were people with dementia identified as a special case which warranted the provision of additional continence products. Clinical guidance on continence assessment and management for community nurses in many parts of England does not address the specific needs of people with dementia living at home or their carers. Nurses working in community settings and those providing clinical leadership in continence care should review their clinical guidance and policies to ensure relevance for people with dementia living at home and their family carers. © 2012