Sample records for nasa modern era

  1. The NASA Modern Era Reanalysis for Research and Applications, Version-2 (MERRA-2)

    NASA Astrophysics Data System (ADS)

    Gelaro, R.; McCarty, W.; Molod, A.; Suarez, M.; Takacs, L.; Todling, R.

    2014-12-01

    The NASA Modern Era Reanalysis for Research Applications Version-2 (MERRA-2) is a reanalysis for the satellite era using an updated version of the Goddard Earth Observing System Data Assimilation System Version-5 (GEOS-5) produced by the Global Modeling and Assimilation Office (GMAO). MERRA-2 will assimilate meteorological and aerosol observations not available to MERRA and includes improvements to the GEOS-5 model and analysis scheme so as to provide an ongoing climate analysis beyond MERRA's terminus. MERRA-2 will also serve as a development milestone for a future GMAO coupled Earth system analysis. Production of MERRA-2 began in June 2014 in four processing streams, with convergence to a single near-real time climate analysis expected by early 2015. This talk provides an overview of the MERRA-2 system developments and key science results. For example, compared with MERRA, MERRA-2 exhibits a well-balanced relationship between global precipitation and evaporation, with significantly reduced sensitivity to changes in the global observing system through time. Other notable improvements include reduced biases in the tropical middle- and upper-tropospheric wind and near-surface temperature over continents.

  2. NASA's Modern Era Retrospective-Analysis for Research and Applications (MERRA): Early Results and Future Directions

    NASA Technical Reports Server (NTRS)

    Schubert, Siegfried

    2008-01-01

    This talk will review the status and progress of the NASA/Global Modeling and Assimilation Office (GMAO) atmospheric global reanalysis project called the Modern Era Retrospective-Analysis for Research and Applications (MERRA). An overview of NASA's emerging capabilities for assimilating a variety of other Earth Science observations of the land, ocean, and atmospheric constituents will also be presented. MERRA supports NASA Earth science by synthesizing the current suite of research satellite observations in a climate data context (covering the period 1979-present), and by providing the science and applications communities with of a broad range of weather and climate data with an emphasis on improved estimates of the hydrological cycle. MERRA is based on a major new version of the Goddard Earth Observing System Data Assimilation System (GEOS-5), that includes the Earth System Modeling Framework (ESMF)-based GEOS-5 atmospheric general circulation model and the new NOAA National Centers for Environmental Prediction (NCEP) unified grid-point statistical interpolation (GST) analysis scheme developed as a collaborative effort between NCEP and the GMAO. In addition to MERRA, the GMAO is developing new capabilities in aerosol and constituent assimilation, ocean, ocean biology, and land surface assimilation. This includes the development of an assimilation capability for tropospheric air quality monitoring and prediction, the development of a carbon-cycle modeling and assimilation system, and an ocean data assimilation system for use in coupled short-term climate forecasting.

  3. Climate Data Guide - Modern Era Retrospective Analysis for Research and Applications, version 2 (MERRA-2)

    NASA Technical Reports Server (NTRS)

    Cullather, Richard; Bosilovich, Michael

    2017-01-01

    The Modern-Era Retrospective analysis for Research and Applications, version 2 (MERRA-2) is a global atmospheric reanalysis produced by the NASA Global Modeling and Assimilation Office (GMAO). It spans the satellite observing era from 1980 to the present. The goals of MERRA-2 are to provide a regularly-gridded, homogeneous record of the global atmosphere, and to incorporate additional aspects of the climate system including trace gas constituents (stratospheric ozone), and improved land surface representation, and cryospheric processes. MERRA-2 is also the first satellite-era global reanalysis to assimilate space-based observations of aerosols and represent their interactions with other physical processes in the climate system. The inclusion of these additional components are consistent with the overall objectives of an Integrated Earth System Analysis (IESA). MERRA-2 is intended to replace the original MERRA product, and reflects recent advances in atmospheric modeling and data assimilation. Modern hyperspectral radiance and microwave observations, along with GPS-Radio Occultation and NASA ozone datasets are now assimilated in MERRA-2. Much of the structure of the data files remains the same in MERRA-2. While the original MERRA data format was HDF-EOS, the MERRA-2 supplied binary data format is now NetCDF4 (with lossy compression to save space).

  4. The Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2)

    NASA Technical Reports Server (NTRS)

    Gelaro, Ronald; McCarty, Will; Randles, Cynthia; Darmenov, Anton; Bosilovich, Michael G.; Cullather, Richard; Buchard, Virginie; Gu, Wei; Putman, William; Schubert, Siegfried D.; hide

    2017-01-01

    The Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2) is the latest atmospheric reanalysis of the modern satellite era produced by NASAs Global Modeling and Assimilation Office (GMAO). MERRA-2 assimilates observation types not available to its predecessor, MERRA, and includes updates to the Goddard Earth Observing System (GEOS) model and analysis scheme so as to provide a viable ongoing climate analysis beyond MERRAs terminus. While addressing known limitations of MERRA, MERRA-2 is also intended to be a development milestone for a future integrated Earth system analysis (IESA) currently under development at GMAO. This paper provides an overview of the MERRA-2 system and various performance metrics. Among the advances in MERRA-2 relevant to IESA are the assimilation of aerosol observations, several improvements to the representation of the stratosphere including ozone, and improved representations of cryospheric processes. Other improvements in the quality of MERRA-2 compared with MERRA include the reduction of some spurious trends and jumps related to changes in the observing system, and reduced biases and imbalances in aspects of the water cycle. Remaining deficiencies are also identified. Production of MERRA-2 began in June 2014 in four processing streams, and converged to a single near-real time stream in mid 2015. MERRA-2 products are accessible online through the NASA Goddard Earth Sciences Data Information Services Center (GESDISC).

  5. NASA EOSDIS Evolution in the BigData Era

    NASA Technical Reports Server (NTRS)

    Lynnes, Christopher

    2015-01-01

    NASA's EOSDIS system faces several challenges in the Big Data Era. Although volumes are large (but not unmanageably so), the variety of different data collections is daunting. That variety also brings with it a large and diverse user community. One key evolution EOSDIS is working toward is to enable more science analysis to be performed close to the data.

  6. Modern Era Retrospective-analysis for Research and Applications (MERRA) Global Water and Energy Budgets

    NASA Technical Reports Server (NTRS)

    Bosilovich, Michael G.; Robertson, Franklin R.; Chen, Junye

    2008-01-01

    The Modern. Era Retrospective-analysis for Research and Applications (MERRA) reanalyses has produced several years of data, on the way to a completing. the 1979-present modern satellite era. Here, we present a preliminary evaluation of those years currently available, includin g comparisons with the existing long reanalyses (ERA40, JRA25 and NCE P I and II) as well as with global data sets for the water and energy cycle Time series shows that the MERRA budgets can change with some of the variations in observing systems. We will present all terms of the budgets in MERRA including the time rates of change and analysis increments (tendency due to the analysis of observations)

  7. NASA STI Program Coordinating Council Eleventh Meeting: NASA STI Modernization Plan

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The theme of this NASA Scientific and Technical Information Program Coordinating Council Meeting was the modernization of the STI Program. Topics covered included the activities of the Engineering Review Board in the creation of the Infrastructure Upgrade Plan, the progress of the RECON Replacement Project, the use and status of Electronic SCAN (Selected Current Aerospace Notices), the Machine Translation Project, multimedia, electronic document interchange, the NASA Access Mechanism, computer network upgrades, and standards in the architectural effort.

  8. Impact of archeomagnetic field model data on modern era geomagnetic forecasts

    NASA Astrophysics Data System (ADS)

    Tangborn, Andrew; Kuang, Weijia

    2018-03-01

    A series of geomagnetic data assimilation experiments have been carried out to demonstrate the impact of assimilating archeomagnetic data via the CALS3k.4 geomagnetic field model from the period between 10 and 1590 CE. The assimilation continues with the gufm1 model from 1590 to 1990 and CM4 model from 1990 to 2000 as observations, and comparisons between these models and the geomagnetic forecasts are used to determine an optimal maximum degree for the archeomagnetic observations, and to independently estimate errors for these observations. These are compared with an assimilation experiment that uses the uncertainties provided with CALS3k.4. Optimal 20 year forecasts in 1990 are found when the Gauss coefficients up to degree 3 are assimilated. In addition we demonstrate how a forecast and observation bias correction scheme could be used to reduce bias in modern era forecasts. Initial experiments show that this approach can reduce modern era forecast biases by as much as 50%.

  9. The Representation of Extra-tropical Cyclones in Recent Re-Analyses: ERA-Interim, NASA-MERRA, NCEP-CFS and JRA25

    NASA Astrophysics Data System (ADS)

    Hodges, K.

    2010-12-01

    Re-analyses are produced using a forecast model, data assimilation system and historical observations. Whilst the observations are common between the re-analyses the way they are assimilated and the forecast model used are often different between the re-analyses which can introduce uncertainty in the representation of particular phenomena between the re-analyses, for example the distribution and properties of weather systems. It is important to inter-compare re-analyses to determine the uncertainty in their representation of the atmosphere, its circulation and weather systems in order to have confidence in their use for studies of the atmosphere and validating climate models. The four recent re-analyses, ERA-Interim, NASA-MERRA, NCEP-CFS and JRA25 are explored and compared for the representation of synoptic scale extra-tropical cyclones. Previous studies of the older re-analyses. ERA40, NCEP-NCAR and DOE has shown that whilst in the NH there was relatively good agreement between the re-analyses in terms of the distribution and properties of extra-tropical cyclones, in the SH there was much larger uncertainty. The newest re-analyses are produced at much higher resolutions than previous re-analyses, in addition more modern data assimilation systems and forecast models have been used. Hence, it would be hoped that the representation of cyclones will be improved to the same extent as that seen in modern NWP systems. This study contrasts extra-tropical cyclones, their distribution and properties, between these new re-analyses and compares them with cyclones in the slightly older though lower resolution JRA25 re-analysis. Results will show that in general in the higher resolution re-analysis more cyclones are identified than in JRA25. In the NH the distribution of storms agrees as well if not better than was the case for the older re-analyses. However, it is in the SH that the largest improvement in agreement is seen for the distribution of storms. For ERA-Interim, NASA

  10. Modern Era Retrospective-analysis for Research and Applications (MERRA) Global Water and Energy Budgets

    NASA Technical Reports Server (NTRS)

    Bosilovich, Michael G.; Chen, Junye

    2009-01-01

    In the Summer of 2009, NASA's Modern Era Retrospective-analysis for Research and Applications (MERRA) will have completed 28 years of global satellite data analyses. Here, we characterize the global water and energy budgets of MERRA, compared with available observations and the latest reanalyses. In this analysis, the climatology of the global average components are studied as well as the separate land and ocean averages. In addition, the time series of the global averages are evaluated. For example, the global difference of precipitation and evaporation generally shows the influence of water vapor observations on the system. Since the observing systems change in time, especially remotely sensed observations of water, significant temporal variations can occur across the 28 year record. These then are also closely connected to changes in the atmospheric energy and water budgets. The net imbalance of the energy budget at the surface can be large and different signs for different reanalyses. In MERRA, the imbalance of energy at the surface tends to improve with time being the smallest during the most recent and abundant satellite observations.

  11. Pelvis Ewing sarcoma: Local control and survival in the modern era.

    PubMed

    Ahmed, Safia K; Robinson, Steven I; Arndt, Carola A S; Petersen, Ivy A; Haddock, Michael G; Rose, Peter S; Issa Laack, Nadia N

    2017-09-01

    Local control for Ewing sarcoma (ES) has improved in modern studies. However, it is unclear if these gains have also been achieved for pelvis tumors. The purpose of this study is to evaluate local control and survival in pelvis ES patients treated in the modern era. All pelvis ES patients diagnosed from 1990 to 2012 and seen at Mayo Clinic were identified. Factors relevant to survival and local control were analyzed. The cohort consisted of 48 patients. Fifty-two percent had metastatic disease at diagnosis. The 5-year overall survival and event-free survival was 73% and 65%, respectively, for localized disease. The 5-year cumulative incidence of local recurrence was 19%, with a 26% incidence for radiation, 13% for surgery, and 0% for surgery + radiation (P = 0.54). All local failures occurred in-field. Sacral involvement by tumor trended toward a higher incidence of local recurrence (hazard ratio 3.06, P = 0.09). Patients treated with definitive radiation doses ≥5,600 cGy had a lower incidence of local recurrence (17% vs. 28%, P = 0.61). Our study demonstrates excellent survival for localized tumors in the modern era. Anatomical localization within the pelvis likely correlates with outcomes. Local control remains problematic, especially for patients treated with definitive radiation. Though statistically not significant, surgery + radiation and definitive radiation dose ≥5,600 cGy were associated with the lowest incidence of local failure, suggesting treatment intensification may improve local control for pelvis ES. © 2017 Wiley Periodicals, Inc.

  12. Conceptual Design and Structural Optimization of NASA Environmentally Responsible Aviation (ERA) Hybrid Wing Body Aircraft

    NASA Technical Reports Server (NTRS)

    Quinlan, Jesse R.; Gern, Frank H.

    2016-01-01

    Simultaneously achieving the fuel consumption and noise reduction goals set forth by NASA's Environmentally Responsible Aviation (ERA) project requires innovative and unconventional aircraft concepts. In response, advanced hybrid wing body (HWB) aircraft concepts have been proposed and analyzed as a means of meeting these objectives. For the current study, several HWB concepts were analyzed using the Hybrid wing body Conceptual Design and structural optimization (HCDstruct) analysis code. HCDstruct is a medium-fidelity finite element based conceptual design and structural optimization tool developed to fill the critical analysis gap existing between lower order structural sizing approaches and detailed, often finite element based sizing methods for HWB aircraft concepts. Whereas prior versions of the tool used a half-model approach in building the representative finite element model, a full wing-tip-to-wing-tip modeling capability was recently added to HCDstruct, which alleviated the symmetry constraints at the model centerline in place of a free-flying model and allowed for more realistic center body, aft body, and wing loading and trim response. The latest version of HCDstruct was applied to two ERA reference cases, including the Boeing Open Rotor Engine Integration On an HWB (OREIO) concept and the Boeing ERA-0009H1 concept, and results agreed favorably with detailed Boeing design data and related Flight Optimization System (FLOPS) analyses. Following these benchmark cases, HCDstruct was used to size NASA's ERA HWB concepts and to perform a related scaling study.

  13. Modernization and unification: Strategic goals for NASA STI program

    NASA Technical Reports Server (NTRS)

    Blados, W.; Cotter, Gladys A.

    1993-01-01

    Information is increasingly becoming a strategic resource in all societies and economies. The NASA Scientific and Technical Information (STI) Program has initiated a modernization program to address the strategic importance and changing characteristics of information. This modernization effort applies new technology to current processes to provide near-term benefits to the user. At the same time, we are developing a long-term modernization strategy designed to transition the program to a multimedia, global 'library without walls.' Notwithstanding this modernization program, it is recognized that no one information center can hope to collect all the relevant data. We see information and information systems changing and becoming more international in scope. We are finding that many nations are expending resources on national systems which duplicate each other. At the same time that this duplication exists, many useful sources of aerospace information are not being collected because of resource limitations. If nations cooperate to develop an international aerospace information system, resources can be used efficiently to cover expanded sources of information. We must consider forming a coalition to collect and provide access to disparate, multidisciplinary sources of information, and to develop standardized tools for documenting and manipulating this data and information. In view of recent technological developments in information science and technology, as well as the reality of scarce resources in all nations, it is time to explore the mutually beneficial possibilities offered by cooperation and international resource sharing. International resources need to be mobilized in a coordinated manner to move us towards this goal. This paper reviews the NASA modernization program and raises for consideration new possibilities for unification of the various aerospace database efforts toward a cooperative international aerospace database initiative that can optimize the cost

  14. The Modern Era of Research in Biosphere Atmosphere Interactions

    NASA Astrophysics Data System (ADS)

    Fung, I. Y.; Sellers, P. J.; Randall, D. A.; Tucker, C. J.; Field, C. B.; Berry, J. A.; Ustin, S.

    2015-12-01

    Dr. Diane Wickland, the Program Scientist for NASA's EOS InterDisciplinary Science (IDS), encouraged and nurtured the growth of the field of global ecology and eco-climatology. This talk reviews the developments in, and integration of, theory, satellite and field observations that enabled the global modeling of biosphere-atmosphere interactions. Emphasis will be placed on the advances made during the EOS era in global datasets and global coupled carbon-climate models. The advances include functional classifications of the land surface using the NDVI, a global terrestrial carbon-energy-water model, and the greening of the CSU GCM. An equally important achievement of the EOS-IDS program is a new generation of multi-disciplinary scientists who are now leaders in the field.

  15. Modernization of the NASA scientific and technical information program

    NASA Technical Reports Server (NTRS)

    Cotter, Gladys A.; Hunter, Judy F.; Ostergaard, K.

    1993-01-01

    The NASA Scientific and Technical Information Program utilizes a technology infrastructure assembled in the mid 1960s to late 1970s to process and disseminate its information products. When this infrastructure was developed it placed NASA as a leader in processing STI. The retrieval engine for the STI database was the first of its kind and was used as the basis for developing commercial, other U.S., and foreign government agency retrieval systems. Due to the combination of changes in user requirements and the tremendous increase in technological capabilities readily available in the marketplace, this infrastructure is no longer the most cost-effective or efficient methodology available. Consequently, the NASA STI Program is pursuing a modernization effort that applies new technology to current processes to provide near-term benefits to the user. In conjunction with this activity, we are developing a long-term modernization strategy designed to transition the Program to a multimedia, global 'library without walls.' Critical pieces of the long-term strategy include streamlining access to sources of STI by using advances in computer networking and graphical user interfaces; creating and disseminating technical information in various electronic media including optical disks, video, and full text; and establishing a Technology Focus Group to maintain a current awareness of emerging technology and to plan for the future.

  16. ERA's Open Rotor Studies Including Shielding for Noise Reduction

    NASA Technical Reports Server (NTRS)

    Van Zante, Dale; Thomas, Russell

    2012-01-01

    The Open Rotor is a modern version of the UnDucted Fan (UDF) that was flight tested in the late 1980's through a partnership between NASA and General Electric (GE). Tests were conducted in the 9' x 15' Low Speed Wind Tunnel and the 8' x 6' Supersonic Wind Tunnel starting in late 2009 and completed in early 2012. Aerodynamic and acoustic data were obtained for takeoff, approach and cruise simulations. GE was the primary partner, but other organizations were involved such as Boeing and Airbus who provided additional hardware for fuselage simulations. This test campaign provided the acoustic and performance characteristics for modern open rotor blades designs." NASA and GE conducted joint systems analysis to evaluate how well new blade designs would perform on a B737 class aircraft, and compared the results to an advanced higher bypass ratio turbofan." Acoustic shielding experiments were performed at NASA GRC and Boeing LSAF facilities to provide data for noise estimates of unconventional aircraft configurations with Open Rotor propulsion systems." The work was sponsored by NASA's aeronautics programs, including the Subsonic Fixed Wing (SFW) and the Environmentally Responsible Aviation (ERA) projects."

  17. Long-Term Model Assimilated Aerosols from MERRA-2: Data and Services at NASA GES DISC

    NASA Technical Reports Server (NTRS)

    Shen, Suhung; Ostrenga, Dana; Huwe, Paul; Vollmer, Bruce; Kempler, Steve

    2016-01-01

    The Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2) is the atmospheric reanalysis conducted with NASA assimilation system GEOS-5. Alongside the meteorological data assimilation, MERRA-2 includes an interactive analysis of aerosols, land, ocean, and ice that feed back into circulation.

  18. Modernization of NASA's Johnson Space Center Chamber: A Payload Transport Rail System to Support Cryogenic Vacuum Optical Testing of the James Webb Space Telescope (JWST)

    NASA Technical Reports Server (NTRS)

    Garcia, Sam; Homan, Jonathan; Speed, John

    2016-01-01

    NASA is the mission lead for the James Webb Space Telescope (JWST), the next of the "Great Observatories", scheduled for launch in 2018. It is directly responsible for the integration and test (I&T) program that will culminate in an end-to-end cryo vacuum optical test of the flight telescope and instrument module in Chamber A at NASA Johnson Space Center. Historic Chamber A is the largest thermal vacuum chamber at Johnson Space Center and one of the largest space simulation chambers in the world. Chamber A has undergone a major modernization effort to support the deep cryogenic, vacuum and cleanliness requirements for testing the JWST. This paper describe the challenges of developing, integrating and modifying new payload rails capable of transporting payloads within the thermal vacuum chamber up to 65,000 pounds. Ambient and Cryogenic Operations required to configure for testing will be explained. Lastly review historical payload configurations stretching from the Apollo program era to current James Webb Space Telescope testing.

  19. Oxide_Oxide Ceramic Matrix Composite (CMC) Exhaust Mixer Development in the NASA Environmentally Responsible Aviation (ERA) Project

    NASA Technical Reports Server (NTRS)

    Kiser, J. Douglas; Bansal, Narottam P.; Szelagowski, James; Sokhey, Jagdish; Heffernan, Tab; Clegg, Joseph; Pierluissi, Anthony; Riedell, Jim; Wyen, Travis; Atmur, Steven; hide

    2015-01-01

    LibertyWorks®, a subsidiary of Rolls-Royce Corporation, first studied CMC (ceramic matrix composite) exhaust mixers for potential weight benefits in 2008. Oxide CMC potentially offered weight reduction, higher temperature capability, and the ability to fabricate complex-shapes for increased mixing and noise suppression. In 2010, NASA was pursuing the reduction of NOx emissions, fuel burn, and noise from turbine engines in Phase I of the Environmentally Responsible Aviation (ERA) Project (within the Integrated Systems Research Program). ERA subtasks, including those focused on CMC components, were being formulated with the goal of maturing technology from Proof of Concept Validation (Technology Readiness Level 3 (TRL 3)) to System/Subsystem or Prototype Demonstration in a Relevant Environment (TRL 6). LibertyWorks®, a subsidiary of Rolls-Royce Corporation, first studied CMC (ceramic matrix composite) exhaust mixers for potential weight benefits in 2008. Oxide CMC potentially offered weight reduction, higher temperature capability, and the ability to fabricate complex-shapes for increased mixing and noise suppression. In 2010, NASA was pursuing the reduction of NOx emissions, fuel burn, and noise from turbine engines in Phase I of the Environmentally Responsible Aviation (ERA) Project (within the Integrated Systems Research Program). ERA subtasks, including those focused on CMC components, were being formulated with the goal of maturing technology from Proof of Concept Validation (Technology Readiness Level 3 (TRL 3)) to System/Subsystem or Prototype Demonstration in a Relevant Environment (TRL 6). Oxide CMC component at both room and elevated temperatures. A TRL˜5 (Component Validation in a Relevant Environment) was attained and the CMC mixer was cleared for ground testing on a Rolls-Royce AE3007 engine for performance evaluation to achieve TRL 6.

  20. The rise of Clostridium difficile infection in lung transplant recipients in the modern era.

    PubMed

    Lee, Janet T; Hertz, Marshall I; Dunitz, Jordan M; Kelly, Rosemary F; D'Cunha, Jonathan; Whitson, Bryan A; Shumway, Sara J

    2013-01-01

    Clostridium difficile infection (CDI) rates have been rising in recent years. We aimed to characterize CDI in lung transplant recipients in the modern era and hypothesized that CDI would increase the mortality risk. We performed a retrospective chart review of patients undergoing transplantation at our center from 1/2006 to 7/2011. Attributes of CDI+ and CDI- groups were compared using Student's t- and chi-square tests (α = 0.05). Multivariate Cox proportional hazard models were used to control for confounding factors. Overall CDI incidence was 22.5%. Seven of 151 patients (4.6%) developed CDI during the initial hospitalization after transplantation (mean time 10.6 ± 6 d) while 27 patients (19.7%) developed CDI after discharge (mean time 467 ± 471 d). Incidence rate was 224.6 cases/100 000 patient-days compared to 110 cases/100 000 patient-days (rate for entire hospital). CDI was not predictive of mortality (HR 2.06, 95% CI 0.94-4.52). CDI rates in lung transplant recipients are high in the modern era. No risk factors for CDI were identified. Although not statistically significant, CDI+ patients had a higher risk of death. The economic burden of CDI and trend toward worse outcomes for CDI patients have important implications for post-operative surveillance of CDI-related complications and need for CDI prophylaxis. © 2013 John Wiley & Sons A/S.

  1. Modern Era Retrospective Restrospective-Analysis for Research and Applications (MERRA) Data and Services at the GES DISC

    NASA Technical Reports Server (NTRS)

    Berrick, Stephen W.; Shen, Suhung; Ostrenga, Dana

    2008-01-01

    The Modern Era Retrospective-analysis for Research and Applications (MERRA) dataset is a NASA satellite era, 30 year (1979 - present), reanalysis using the Goddard Earth Observing System Data Assimilation System, Version 5 (GEOS-5). The project, run out of NASA's Global Modeling and Assimilation Office at Goddard Space Flight Center, provides the science and application communities with a state-of-the-art global analysis with emphasis on improved estimates of the hydrological cycle over a broad range of weather and climate time scales. MERRA products are generated as a long-term synthesis that places the NASA EOS suite of observations in a climate context. The MERRA analysis is performed at a horizontal resolution of 2/3 longitude x 1/2 latitude (540x361 global gridpoints) with observational analyses every 6 hours. The MERRA output data will include 3 dimensional state fields for every 6 hourly analysis cycle on 42 pressure levels (or 72 terrain following model coordinate levels) from the surface through the stratosphere. Several data products are specifically designed to support chemistry and stratosphere transport modeling. The 2 dimensional surface and atmospheric diagnostics (numbering 259) are being stored on the native grid at 1 hourly intervals. These include radiation and vertical integrals of the atmosphere for water and energy budget studies and also surface diagnostics where the diurnal cycle is important. The one hourly surface and near surface data product will also facilitate research on the integrated analysis of Earth system observations in the land, ocean and cryosphere. The MERRA products are archived and distributed by the Goddard Earth Sciences Data and Information Services Center (GES DISC) through its Modeling DISC Web (MDISC) portal. Multiple data access methods and services are available for MERRA data through MDISC: (1) Mirador offers a quick, comprehensive search of MERRA and all GES DISC archived data holdings, allowing searches on

  2. Social Studies in the Modern Era: A Case Study of Effective Teachers' Use of Literacy and Technology

    ERIC Educational Resources Information Center

    Curry, Kristal; Cherner, Todd

    2016-01-01

    The purpose of this research project was to highlight the practices and philosophies of two effective--but different--social studies teachers who balance the demands of teaching in the modern era while honoring their own philosophies for teaching social studies. This project was ground in the theoretical framework provided by TPACK and used a case…

  3. Modernization of NASA's Johnson Space Center Chamber: A Liquid Nitrogen System to Support Cryogenic Vacuum Optical Testing of the James Webb Space Telescope (JWST)

    NASA Technical Reports Server (NTRS)

    Garcia, Sammy; Homan, Jonathan; Montz, Michael

    2016-01-01

    NASA is the mission lead for the James Webb Space Telescope (JWST), the next of the “Great Observatories”, scheduled for launch in 2018. It is directly responsible for the integration and test (I&T) program that will culminate in an end-to-end cryo vacuum optical test of the flight telescope and instrument module in Chamber A at NASA Johnson Space Center. Historic Chamber A is the largest thermal vacuum chamber at Johnson Space Center and one of the largest space simulation chambers in the world. Chamber A has undergone a major modernization effort to support the deep cryogenic, vacuum and cleanliness requirements for testing the JWST. This paper describes the steps performed in efforts to convert the existing the 60’s era Liquid Nitrogen System from a forced flow (pumped) process to a natural circulation (thermo-siphon) process. In addition, the paper will describe the dramatic conservation of liquid nitrogen to support the long duration thermal vacuum testing. Lastly, describe the simplistic and effective control system which results in zero to minimal human inputs during steady state conditions.

  4. Tuberculosis and the role of war in the modern era.

    PubMed

    Drobniewski, F A; Verlander, N Q

    2000-12-01

    Tuberculosis (TB) remains a major global health problem; historically, major wars have increased TB notifications. This study evaluated whether modern conflicts worldwide affected TB notifications between 1975 and 1995. Dates of conflicts were obtained and matched with national TB notification data reported to the World Health Organization. Overall notification rates were calculated pre and post conflict. Poisson regression analysis was applied to all conflicts with sufficient data for detailed trend analysis. Thirty-six conflicts were identified, for which 3-year population and notification data were obtained. Overall crude TB notification rates were 81.9 and 105.1/100,000 pre and post start of conflict in these countries. Sufficient data existed in 16 countries to apply Poisson regression analysis to model 5-year pre and post start of conflict trends. This analysis indicated that the risk of presenting with TB in any country 2.5 years after the outbreak of conflict relative to 2.5 years before the outbreak was 1.016 (95%CI 0.9435-1.095). The modelling suggested that in the modern era war may not significantly damage efforts to control TB in the long term. This might be due to the limited scale of most of these conflicts compared to the large-scale civilian disruption associated with 'world wars'. The management of TB should be considered in planning post-conflict refugee and reconstruction programmes.

  5. Evaluation of the Modern Era Retrospective-Analysis for Research and Applications (MERRA) Global Water and Energy Budgets

    NASA Technical Reports Server (NTRS)

    Bosilovich, Michael G.; Robertson, F. R.; Chen, J.

    2010-01-01

    The Modern Era Retrospective-analysis for Research and Applications (MERRA) reanalyses has completed 27 years of data) soon to be caught up to present. Here) we present an evaluation of those years currently available) including comparisons with the existing long reanalyses (ERA40) JRA25 and NCEP I and II) as well as with global data sets for the water and energy cycle. Time series shows that the MERRA budgets can change with some of the variations in observing systems, but that the magnitude of energy imbalance in the system is improved with more observations. We will present all terms of the budgets in MERRA including the time rates of change and analysis increments (tendency due to the analysis of observations).

  6. NASA ERA Integrated CFD for Wind Tunnel Testing of Hybrid Wing-Body Configuration

    NASA Technical Reports Server (NTRS)

    Garcia, Joseph A.; Melton, John E.; Schuh, Michael; James, Kevin D.; Long, Kurtis R.; Vicroy, Dan D.; Deere, Karen A.; Luckring, James M.; Carter, Melissa B.; Flamm, Jeffrey D.; hide

    2016-01-01

    The NASA Environmentally Responsible Aviation (ERA) Project explored enabling technologies to reduce impact of aviation on the environment. One project research challenge area was the study of advanced airframe and engine integration concepts to reduce community noise and fuel burn. To address this challenge, complex wind tunnel experiments at both the NASA Langley Research Center's (LaRC) 14'x22' and the Ames Research Center's 40'x80' low-speed wind tunnel facilities were conducted on a BOEING Hybrid Wing Body (HWB) configuration. These wind tunnel tests entailed various entries to evaluate the propulsion-airframe interference effects, including aerodynamic performance and aeroacoustics. In order to assist these tests in producing high quality data with minimal hardware interference, extensive Computational Fluid Dynamic (CFD) simulations were performed for everything from sting design and placement for both the wing body and powered ejector nacelle systems to the placement of aeroacoustic arrays to minimize its impact on vehicle aerodynamics. This paper presents a high-level summary of the CFD simulations that NASA performed in support of the model integration hardware design as well as the development of some CFD simulation guidelines based on post-test aerodynamic data. In addition, the paper includes details on how multiple CFD codes (OVERFLOW, STAR-CCM+, USM3D, and FUN3D) were efficiently used to provide timely insight into the wind tunnel experimental setup and execution.

  7. NASA ERA Integrated CFD for Wind Tunnel Testing of Hybrid Wing-Body Configuration

    NASA Technical Reports Server (NTRS)

    Garcia, Joseph A.; Melton, John E.; Schuh, Michael; James, Kevin D.; Long, Kurt R.; Vicroy, Dan D.; Deere, Karen A.; Luckring, James M.; Carter, Melissa B.; Flamm, Jeffrey D.; hide

    2016-01-01

    NASAs Environmentally Responsible Aviation (ERA) Project explores enabling technologies to reduce aviations impact on the environment. One research challenge area for the project has been to study advanced airframe and engine integration concepts to reduce community noise and fuel burn. In order to achieve this, complex wind tunnel experiments at both the NASA Langley Research Centers (LaRC) 14x22 and the Ames Research Centers 40x80 low-speed wind tunnel facilities were conducted on a Boeing Hybrid Wing Body (HWB) configuration. These wind tunnel tests entailed various entries to evaluate the propulsion airframe interference effects including aerodynamic performance and aeroacoustics. In order to assist these tests in producing high quality data with minimal hardware interference, extensive Computational Fluid Dynamic (CFD) simulations were performed for everything from sting design and placement for both the wing body and powered ejector nacelle systems to the placement of aeroacoustic arrays to minimize its impact on the vehicles aerodynamics. This paper will provide a high level summary of the CFD simulations that NASA performed in support of the model integration hardware design as well as some simulation guideline development based on post-test aerodynamic data. In addition, the paper includes details on how multiple CFD codes (OVERFLOW, STAR-CCM+, USM3D, and FUN3D) were efficiently used to provide timely insight into the wind tunnel experimental setup and execution.

  8. Symptomatic Perihepatic Fluid Collections After Hepatic Resection in the Modern Era.

    PubMed

    Konstantinidis, Ioannis T; Mastrodomenico, Pedro; Sofocleous, Constantinos T; Brown, Karen T; Getrajdman, George I; Gönen, Mithat; Allen, Peter J; Kingham, T Peter; DeMatteo, Ronald P; Fong, Yuman; Jarnagin, William R; D'Angelica, Michael I

    2016-04-01

    Improvements in liver surgery have led to decreased mortality rates. Symptomatic perihepatic collections (SPHCs) requiring percutaneous drainage remain a significant source of morbidity. A single institution's prospectively maintained hepatic resection database was reviewed to identify patients who underwent hepatectomy between January 2004 and February 2012. Data from 2173 hepatectomies performed in 2040 patients were reviewed. Overall, 200 (9%) patients developed an SPHC, the majority non-bilious (75.5%) and infected (54%). Major hepatic resections, larger than median blood loss (≥360 ml), use of surgical drains, and simultaneous performance of a colorectal procedure were associated with an SPHC on multivariate analysis. Non-bilious, non-infected (NBNI) collections were associated with lower white blood cell (WBC) counts, absence of a bilio-enteric anastomosis, use of hepatic arterial infusion pump (HAIP), and presence of metastatic disease, and resolved more frequently with a single interventional radiology (IR) procedure (85 vs. 46.5%, p < 0.001) more quickly (15 vs. 30 days, p = 0.001). SPHCs developed in 9% of patients in a modern series of hepatic resections, and in one third were non-bilious and non-infected. In the era of modern interventional radiology, the need for re-operation for SPHC is exceedingly rare. A significant proportion of minimally symptomatic SPHC patients may not require drainage, and strategies to avoid unnecessary drainage are warranted.

  9. The NASA Environmentally Responsible Aviation Project/General Electric Open Rotor Test Campaign

    NASA Technical Reports Server (NTRS)

    Van Zante, Dale

    2013-01-01

    The Open Rotor is a modern version of the UnDucted Fan (UDF) that was flight tested in the late 1980's through a partnership between NASA and General Electric (GE). Tests were conducted in the 9'x15' Low Speed Wind Tunnel and the 8'x6' Supersonic Wind Tunnel starting in late 2009 and completed in early 2012. Aerodynamic and acoustic data were obtained for takeoff, approach and cruise simulations. GE was the primary partner, but other organizations were involved such as Boeing and Airbus who provided additional hardware for fuselage simulations. This test campaign provided the acoustic and performance characteristics for modern open rotor blades designs." NASA and GE conducted joint systems analysis to evaluate how well new blade designs would perform on a B737 class aircraft, and compared the results to an advanced higher bypass ratio turbofan." Acoustic shielding experiments were performed at NASA GRC and Boeing LSAF facilities to provide data for noise estimates of unconventional aircraft configurations with Open Rotor propulsion systems." The work was sponsored by NASA's aeronautics programs, including the Subsonic Fixed Wing (SFW) and the Environmentally Responsible Aviation (ERA) projects."

  10. Significance of R1 Resection for Advanced Colorectal Liver Metastases in the Era of Modern Effective Chemotherapy.

    PubMed

    Laurent, Christophe; Adam, Jean-Philippe; Denost, Quentin; Smith, Denis; Saric, Jean; Chiche, Laurence

    2016-05-01

    The prognosis impact of positive margins after resection of colorectal liver metastases (CLM) in patients treated with modern effective chemotherapy has not been elucidated. The objective was to compare oncologic outcomes after R0 and R1 resections in the era of modern effective chemotherapy. Between 1999 and 2010, all consecutive patients undergoing liver resection for CLM were analyzed retrospectively. Patients with extrahepatic metastases, macroscopic residual tumor, treated with combined radiofrequency, or not treated with chemotherapy were excluded. Survival and recurrence after R0 (tumor-free margin >0 mm) and R1 resections were analyzed. Among 466 patients undergoing hepatectomy for CLM, 191 were eligible. Of them, 164 (86 %) received preoperative chemotherapy and 105 (55 %) received postoperative chemotherapy. R1 resection (10 %) was comparable in patients treated or not by preoperative chemotherapy. R1 status was associated with more intrahepatic recurrences. Overall survival (OS) (44 vs. 61 %; p = 0.047) and disease-free survival (DFS) (8 vs. 26 %; p = 0.082) were lower in patients after R1 compared to R0 resection (32 months of median follow-up). Preoperative chemotherapy and major hepatectomy were prognostic factors of survival, whereas postoperative chemotherapy was a protective factor from recurrences. In patients treated with preoperative chemotherapy, OS and DFS were similar between R1 and R0 resections (40 vs. 55 %, p = 0.104 and 9 vs. 22 %, p = 0.174, respectively). In the era of modern effective chemotherapy, R1 resection leads to more intrahepatic recurrences but did not affect OS in selected patient responders to neoadjuvant chemotherapy. Postoperative chemotherapy protects from recurrences whatever the margin resection status.

  11. When and how should we manage thoracic aortic injuries in the modern era?

    PubMed

    Bottet, Benjamin; Bouchard, François; Peillon, Christophe; Baste, Jean-Marc

    2016-12-01

    A best evidence topic in cardiovascular surgery was written according to a structured protocol. The question addressed was what are the optimum treatment modality and timing of intervention for blunt thoracic aortic injury (BTAI) in the modern era? Of the 697 papers found using the reported search, 14 (5 meta-analyses, 2 prospective and 7 retrospective studies) represented the best evidence to answer the clinical question. The author, journal, country, date of publication, patient group studied, study type, relevant outcomes, results and weakness of these papers are tabulated. All five meta-analyses reported a reduction in mortality with thoracic endovascular aortic repair (TEVAR) compared with open repair (OR), but only four found the same benefit on paraplegia rate. Similarly, the two prospective and four retrospective studies showed significantly lower mortality with TEVAR than with OR. Only one study (a meta-analysis) reported a significantly lower stroke rate with TEVAR than with OR, whereas the 13 others reported a similar or even higher stroke rate. Other complication rates were identical. Four studies demonstrated that non-operative management (NOM) as a treatment option for BTAI was associated with increased mortality, even if it has declined in recent years. One study emphasized that some cases with minimal aortic injuries (Grade I and II on CT scan) could benefit from NOM. Regarding the timing of repair, only three studies analysed outcomes of delayed repair and reported significantly lower mortality than for early repair. We conclude that with lower mortality and similar overall complications including paraplegia but higher stroke rate, TEVAR is the most suitable treatment for BTAI in the modern era, where expertise exists, especially for cases of multiple associated injuries and in the older age group. Delayed aortic repair can be proposed based on CT scan analysis, but emergent repair should still be advocated for imminent free aortic rupture. NOM

  12. History of Thermal Barrier Coatings for Gas Turbine Engines: Emphasizing NASA's Role from 1942 to 1990

    NASA Technical Reports Server (NTRS)

    Miller, Robert A.

    2009-01-01

    NASA has played a central role in the development of thermal barrier coatings (TBCs) for gas turbine applications. This report discusses the history of TBCs emphasizing the role NASA has played beginning with (1) frit coatings in the 1940s and 1950s; (2) thermally sprayed coatings for rocket application in the 1960s and early 1970s; (3) the beginnings of the modern era of turbine section coatings in the mid 1970s; and (4) failure mechanism and life prediction studies in the 1980s and 1990s. More recent efforts are also briefly discussed.

  13. American Meteorological Society (AMS) - The Modern Era Retrospective-Analysis for Research and Applications (MERRA) Data and Accessibility

    NASA Technical Reports Server (NTRS)

    daSilva, Arlindo

    2009-01-01

    The AM Short Course on The Modern Era Retrospective-analysis for Research and Applications (MERRA) data and accessibility will be held on January 11, 2009 preceding the 89th Annual Meeting in Phoenix, Arizona. Preliminary programs, registration, hotel, and general information will be posted on the AMS Web site in mid-September 2008. Retrospective-analyses (or reanalyses) have been established as an important tool in weather and climate research over the last decade. As computer power increases, the data assimilation and modeling systems improve and become more advanced, the input data quality increases and so reanalyses become more reliable. In 2008, NASA Global Modeling and Assimilation Office began producing a new reanalysis called the Modem Era Retrospective-analysis for Research and Applications (MERRA). The initial data from the reanalysis has been made available to the community and should be complete through 30 years (1979-present) by Fall of 2009. MERRA has taken advantage of the advancement of computing resources to provide users more data than previously available. The native spatial resolution is nominally 1/2 degrees and the surface two dimensional data are one hourly frequency. In addition to the meteorological analysis data, complete mass, energy and momentum budget data and also stratospheric data are provided. The eventual data holdings will exceed 150Tb. In order to facilitate user accessibility to the data, it will be stored in online hard drives (not tape storage) and available through several portals. Subsetting tools will also be available to allow users to tailor their data requests. The goals of this short course are to provide hands on users of reanalyses instruction on MERRA systems and also interactive experience with the online data and access tools. The course is intended for students and research scientists who will be actively interested in accessing and applying MERRA data in their weather, climate or applications work. The course has

  14. A Multifaceted Approach to Modernizing NASA's Advanced Multi-Mission Operations System (AMMOS) System Architecture

    NASA Technical Reports Server (NTRS)

    Estefan, Jeff A.; Giovannoni, Brian J.

    2014-01-01

    The Advanced Multi-Mission Operations Systems (AMMOS) is NASA's premier space mission operations product line offering for use in deep-space robotic and astrophysics missions. The general approach to AMMOS modernization over the course of its 29-year history exemplifies a continual, evolutionary approach with periods of sponsor investment peaks and valleys in between. Today, the Multimission Ground Systems and Services (MGSS) office-the program office that manages the AMMOS for NASA-actively pursues modernization initiatives and continues to evolve the AMMOS by incorporating enhanced capabilities and newer technologies into its end-user tool and service offerings. Despite the myriad of modernization investments that have been made over the evolutionary course of the AMMOS, pain points remain. These pain points, based on interviews with numerous flight project mission operations personnel, can be classified principally into two major categories: 1) information-related issues, and 2) process-related issues. By information-related issues, we mean pain points associated with the management and flow of MOS data across the various system interfaces. By process-related issues, we mean pain points associated with the MOS activities performed by mission operators (i.e., humans) and supporting software infrastructure used in support of those activities. In this paper, three foundational concepts-Timeline, Closed Loop Control, and Separation of Concerns-collectively form the basis for expressing a set of core architectural tenets that provides a multifaceted approach to AMMOS system architecture modernization intended to address the information- and process-related issues. Each of these architectural tenets will be further explored in this paper. Ultimately, we envision the application of these core tenets resulting in a unified vision of a future-state architecture for the AMMOS-one that is intended to result in a highly adaptable, highly efficient, and highly cost

  15. Recovering Nimbus era Observations at the NASA GES DISC

    NASA Astrophysics Data System (ADS)

    Meyer, D. J.; Johnson, J. E.; Esfandiari, A. E.; Zamkoff, E. B.; Al-Jazrawi, A. F.; Gerasimov, I. V.; Alcott, G. T.

    2017-12-01

    Between 1964 and 1978, NASA launched a series of seven Nimbus meteorological satellites which provided Earth observations for 30 years. These satellites, carrying a total of 33 instruments to observe the Earth at visible, infrared, ultraviolet, and microwave wavelengths, revolutionized weather forecasting, provided early observations of ocean color and atmospheric ozone, and prototyped location-based search and rescue capabilities. The Nimbus series paved the way for a number of currently operational systems such as the EOS Terra, Aqua and Aura platforms.The original data archive included both magnetic tapes and film media. These media are well past their expected end of life, placing at risk valuable data that are critical to extending the history of Earth observations back in time. GES DISC has been incorporating these data into a modern online archive by recovering the digital data files from the tapes, and scanning images of the data from film strips. The original data products were written on obsolete hardware systems in outdated file formats, and in the absence of metadata standards at that time, were often written in proprietary file structures. Through a tedious and laborious process, oft-corrupted data are recovered, and incomplete metadata and documentation are reconstructed.

  16. Managing NASA in the Apollo era

    NASA Technical Reports Server (NTRS)

    Levine, A. S.

    1982-01-01

    The administration and organization are described and analyzed. Policies on manpower and the budgetary process for contracting for research development, the structure of NASA-DOD relations, and program planning are discussed.

  17. Recovering Nimbus Era Observations at the NASA GES DISC

    NASA Technical Reports Server (NTRS)

    Meyer, D.; Johnson, J.; Esfandiari, A.; Zamkoff, E.; Al-Jazrawi, A.; Gerasimov, I.; Alcott, G.

    2017-01-01

    Between 1964 and 1978, NASA launched a series of seven Nimbus meteorological satellites which provided Earth observations for 30 years. These satellites, carrying a total of 33 instruments to observe the Earth at visible, infrared, ultraviolet, and microwave wavelengths, revolutionized weather forecasting, provided early observations of ocean color and atmospheric ozone, and prototyped location-based search and rescue capabilities. The Nimbus series paved the way for a number of currently operational systems such as the EOS (Earth Observation System) Terra, Aqua, and Aura platforms. The original data archive includes both magnetic tapes and film media. These media are well past their expected end of life, placing at risk valuable data that are critical to extending the history of Earth observations back in time. GES DISC (Goddard Earth Sciences Data and Information Services Center) has been incorporating these data into a modern online archive by recovering the digital data files from the tapes, and scanning images of the data from film strips. The digital data products were written on obsolete hardware systems in outdated file formats, and in the absence of metadata standards at that time, were often written in proprietary file structures. Through a tedious and laborious process, oft-corrupted data are recovered, and incomplete metadata and documentation are reconstructed.

  18. Margin Status Remains an Important Determinant of Survival after Surgical Resection of Colorectal Liver Metastases in the Era of Modern Chemotherapy

    PubMed Central

    Andreou, Andreas; Aloia, Thomas A.; Brouquet, Antoine; Dickson, Paxton V.; Zimmitti, Giuseppe; Maru, Dipen M.; Kopetz, Scott; Loyer, Evelyne M.; Curley, Steven A.; Abdalla, Eddie K.; Vauthey, Jean-Nicolas

    2013-01-01

    Objective To determine the impact of surgical margin status on overall survival (OS) of patients undergoing hepatectomy for colorectal liver metastases (CLM) after modern preoperative chemotherapy. Summary Background Data In the era of effective chemotherapy for CLM, the association between surgical margin status and survival has become controversial. Methods Clinicopathologic data and outcomes for 378 patients treated with modern preoperative chemotherapy and hepatectomy were analyzed. The effect of positive margins on OS was analyzed in relation to pathologic and computed tomography-based morphologic response to chemotherapy. Results Fifty-two of 378 resections (14%) were R1 resections (tumor-free margin < 1 mm). The 5-year OS rates for patients with R0 resection (margin ≥ 1 mm) and R1 resection were 55% and 26%, respectively (P=0.017). Multivariate analysis identified R1 resection (P=0.03) and minor pathologic response to chemotherapy (P=0.002) as the 2 factors independently associated with worse survival. The survival benefit associated with negative margins (R0 vs. R1 resection) was greater in patients with suboptimal morphologic response (5-year OS rate: 62% vs. 11%, P=0.007) than in patients with optimal response (3-year OS rate: 92% vs. 88%, P=0.917) and greater in patients with minor pathologic response (5-year OS rate: 46% vs. 0%, P=0.002) than in patients with major response (5-year OS rate: 63% vs. 67%, P=0.587). Conclusions In the era of modern chemotherapy, negative margins remain an important determinant of survival and should be the primary goal of surgical therapy. The impact of positive margins is most pronounced in patients with suboptimal response to systemic therapy. PMID:23426338

  19. Margin status remains an important determinant of survival after surgical resection of colorectal liver metastases in the era of modern chemotherapy.

    PubMed

    Andreou, Andreas; Aloia, Thomas A; Brouquet, Antoine; Dickson, Paxton V; Zimmitti, Giuseppe; Maru, Dipen M; Kopetz, Scott; Loyer, Evelyne M; Curley, Steven A; Abdalla, Eddie K; Vauthey, Jean-Nicolas

    2013-06-01

    To determine the impact of surgical margin status on overall survival (OS) of patients undergoing hepatectomy for colorectal liver metastases after modern preoperative chemotherapy. In the era of effective chemotherapy for colorectal liver metastases, the association between surgical margin status and survival has become controversial. Clinicopathologic data and outcomes for 378 patients treated with modern preoperative chemotherapy and hepatectomy were analyzed. The effect of positive margins on OS was analyzed in relation to pathologic and computed tomography-based morphologic response to chemotherapy. Fifty-two of 378 resections (14%) were R1 resections (tumor-free margin <1 mm). The 5-year OS rates for patients with R0 resection (margin ≥1 mm) and R1 resection were 55% and 26%, respectively (P = 0.017). Multivariate analysis identified R1 resection (P = 0.03) and a minor pathologic response to chemotherapy (P = 0.002) as the 2 factors independently associated with worse survival. The survival benefit associated with negative margins (R0 vs R1 resection) was greater in patients with suboptimal morphologic response (5-year OS rate: 62% vs 11%; P = 0.007) than in patients with optimal response (3-year OS rate: 92% vs 88%; P = 0.917) and greater in patients with a minor pathologic response (5-year OS rate: 46% vs 0%; P = 0.002) than in patients with a major response (5-year OS rate: 63% vs 67%; P = 0.587). In the era of modern chemotherapy, negative margins remain an important determinant of survival and should be the primary goal of surgical therapy. The impact of positive margins is most pronounced in patients with suboptimal response to systemic therapy.

  20. The history of varicocele: from antiquity to the modern ERA.

    PubMed

    Marte, Antonio

    2018-01-01

    Men have most likely been affected by varicocele since the assumption of the upright position. In De Medicina, written during the first century AD, Celsus credits the Greeks with the first description of a varicocele, and he recorded his own acute observation: "The veins are swollen and twisted over the testicle, which becomes smaller". Celsus himself is credited with the distinction between varicocele (dilation of surface veins) and "cirsocele" (dilation of deep veins). There has been a long history of treatment attempts and failures, some of which are remarkably strange, that have sometimes culminated in tragedy, as in the case of French professor Jacques-Mathieu Delpech (1772- 1832). Although some questions regarding the etiopathology and treatment of varicocele remain unanswered, a succession of more or less conservative attempts involving all medical cultures has been performed throughout history. The report by W.S. Tulloch in 1952 brought varicocele into the era of modern evidence-based medicine, and varicocele surgery finally progressed beyond the aim of merely relieving scrotal pain and swelling. From 1970 to 2000, varicocelectomies gained worldwide attention for the treatment of male infertility. Several innovative procedures to correct varicoceles began to appear in the world's literature as interventional radiology, microsurgery, laparoscopy, and robotics, while comprehensive review articles were also published on the subject of varicocelectomies. Microsurgery is nowadays used worldwide and it can be considered to be the gold standard for correcting infertility linked to varicocele. Copyright® by the International Brazilian Journal of Urology.

  1. NASA Prediction of Worldwide Energy Resource High Resolution Meteorology Data For Sustainable Building Design

    NASA Technical Reports Server (NTRS)

    Chandler, William S.; Hoell, James M.; Westberg, David; Zhang, Taiping; Stackhouse, Paul W., Jr.

    2013-01-01

    A primary objective of NASA's Prediction of Worldwide Energy Resource (POWER) project is to adapt and infuse NASA's solar and meteorological data into the energy, agricultural, and architectural industries. Improvements are continuously incorporated when higher resolution and longer-term data inputs become available. Climatological data previously provided via POWER web applications were three-hourly and 1x1 degree latitude/longitude. The NASA Modern Era Retrospective-analysis for Research and Applications (MERRA) data set provides higher resolution data products (hourly and 1/2x1/2 degree) covering the entire globe. Currently POWER solar and meteorological data are available for more than 30 years on hourly (meteorological only), daily, monthly and annual time scales. These data may be useful to several renewable energy sectors: solar and wind power generation, agricultural crop modeling, and sustainable buildings. A recent focus has been working with ASHRAE to assess complementing weather station data with MERRA data. ASHRAE building design parameters being investigated include heating/cooling degree days and climate zones.

  2. Modern scientific evidence pertaining to criminal investigations in the Chosun dynasty era (1392-1897 A.C.E.) in Korea.

    PubMed

    Nam, Yun Sik; Won, Sung-Ok; Lee, Kang-Bong

    2014-07-01

    A guidebook detailing the process of forensic investigation was written in 1440 A.C.E. It outlines the fundamentals and details of each element of criminal investigation during the era of the Chosun dynasty in Korea. Because this old guidebook was written in terms of personal experience rather than on scientific basis, it includes many fallacies from the perspective of modern forensic science. However, the book describes methods to form a scientific basis for the experiments performed. We demonstrate the modern scientific basis for ancient methods to monitor trace amounts of blood and detect lethal arsenic poisoning from a postmortem examination as described in this old forensic guidebook. Traces of blood and arsenic poisoning were detected according to the respective color changes of brownish red, due to the reaction of ferric ions in blood with acetic ions of vinegar, and dark blue, due to the reaction of silver with arsenic sulfide. © 2014 American Academy of Forensic Sciences.

  3. Hospital Volume and Operative Mortality in the Modern Era

    PubMed Central

    Reames, Bradley N.; Ghaferi, Amir A.; Birkmeyer, John D.; Dimick, Justin B.

    2014-01-01

    Background It is generally accepted that hospital volume is associated with mortality in high-risk procedures. However, as surgical safety has improved over the last decade, recent evidence has suggested that the inverse relationship has diminished or been eliminated. Objective To determine whether the relationship between hospital volume and mortality has changed over time. Methods Using national Medicare claims data from 2000 through 2009, we examined mortality among 3,282,127 patients who underwent one of eight gastrointestinal, cardiac, or vascular procedures. Hospitals were stratified into quintiles of operative volume. Using multivariable logistic regression models to adjust for patient characteristics, we examined the relationship between hospital volume and mortality, and assessed for changes over time. We performed sensitivity analyses using hierarchical logistic regression modeling with hospital-level random effects to confirm our results. Results Throughout the ten-year period, a significant inverse relationship was observed in all procedures. In five of the eight procedures studied, the strength of the volume-outcome relationship increased over time. In esophagectomy, for example, the adjusted odds ratio of mortality in very low volume hospitals compared to very high volume hospitals increased from 2.25 [95%CI: 1.57-3.23] in 2000-2001 to 3.68 [95%CI: 2.66-5.11] in 2008-2009. Only pancreatectomy showed a notable decrease in strength of the relationship over time, from 5.83 [95%CI: 3.64-9.36] in 2000-2001, to 3.08 [95%CI: 2.07 - 4.57] in 2008-2009. Conclusion For all procedures examined, higher volume hospitals had significantly lower mortality rates compared to lower volume hospitals. Despite recent improvements in surgical safety, the strong inverse relationship between hospital volume and mortality persists in the modern era. PMID:24368634

  4. Prolonged survival of patients with non-small-cell lung cancer with leptomeningeal carcinomatosis in the modern treatment era.

    PubMed

    Riess, Jonathan W; Nagpal, Seema; Iv, Michael; Zeineh, Michael; Gubens, Matthew A; Ramchandran, Kavitha; Neal, Joel W; Wakelee, Heather A

    2014-05-01

    Leptomeningeal carcinomatosis (LM) is a severe complication of non-small-cell lung cancer (NSCLC) historically associated with poor prognosis. New chemotherapeutic and targeted treatments could potentially affect the natural history of LM. Patients with a pathologic diagnosis of NSCLC with LM treated at Stanford between 2003 and 2011 were identified via institutional databases and medical records. LM was defined by cerebrospinal fluid (CSF) that was positive for malignant cells or by LM enhancement on magnetic resonance imaging with gadolinium contrast. Retrospective, landmark analyses were performed to estimate survival. Statistical analyses were performed using SAS Enterprise Guide, version 4.3. LM was identified in 30 patients. All cases were adenocarcinoma; 60% of patients had a known or suspected driver mutation. The mean age was 58 years. Of the 30 patients, 67% were women; 70% were nonsmokers; 27% initially presented with LM; 84% received systemic treatment at or after development of LM; and 53% of these patients received modern systemic therapy for their LM, defined as a regimen containing pemetrexed, bevacizumab, or a tyrosine kinase inhibitor. Mean overall survival after LM diagnosis was 6 months (95% CI, 3-12). Patients who received modern systemic therapy for LM had decreased hazard of death (hazard ratio [HR], 0.24; P = .007). In this retrospective, single-institution analysis, median survival with LM was higher compared with historical experience. Patients who received modern systemic therapy for their LM had particularly good outcomes. These data provide evidence for improving survival outcomes in the modern treatment era for this difficult-to-treat complication. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. An Overview of NASA's Intelligent Systems Program

    NASA Technical Reports Server (NTRS)

    Cooke, Daniel E.; Norvig, Peter (Technical Monitor)

    2001-01-01

    NASA and the Computer Science Research community are poised to enter a critical era. An era in which - it seems - that each needs the other. Market forces, driven by the immediate economic viability of computer science research results, place Computer Science in a relatively novel position. These forces impact how research is done, and could, in worst case, drive the field away from significant innovation opting instead for incremental advances that result in greater stability in the market place. NASA, however, requires significant advances in computer science research in order to accomplish the exploration and science agenda it has set out for itself. NASA may indeed be poised to advance computer science research in this century much the way it advanced aero-based research in the last.

  6. Long-term Outcomes of Cytomegalovirus Retinitis in the Era of Modern Antiretroviral Therapy; Results from a United States Cohort

    PubMed Central

    Jabs, Douglas A.; Ahuja, Alka; Van Natta, Mark L.; Lyon, Alice T.; Yeh, Steven; Danis, Ronald

    2015-01-01

    Objectives To describe the long-term outcomes of patients with cytomegalovirus (CMV) retinitis and the acquired immunodeficiency syndrome (AIDS)in the modern era of combination antiretroviral therapy. Design Prospective, observational, cohort study Participants Patients with AIDS and CMV retinitis Testing Immune recovery, defined as a CD4+ T cell count>100 cells/μL for ≥ 3 months. Main outcome measures Mortality, visual impairment (visual acuity worse than 20/40) and blindness (visual acuity 20/200 or worse) on logarithmic visual acuity charts, loss of visual field on quantitative Goldmann perimetry. Results Patients without immune recovery had a mortality of 44.4/100 person years (PY), and a median survival of 13.5 months after the diagnosis of CMV retinitis, whereas those with immune recovery had a mortality of 2.7/100 PY (P<0.001), and an estimated median survival of 27.0 years after the diagnosis of CMV retinitis. The rates of bilateral visual impairment and blindness were 0.9/100 PY and 0.4/100 PY, respectively, and were similar between those with and without immune recovery. Among those with immune recovery, the rate of visual field loss was ~1% of the normal field/year, whereas among those without immune recovery it was ~7% of the normal field/year. Conclusions Among persons with CMV retinitis and AIDS, if there is immune recovery, long-term survival is likely, whereas if there is no immune recovery, the mortality rate is substantial. Although higher than the rates seen in the non-HIV-infected population, the rates of bilateral visual impairment and blindness are low, especially when compared to rates seen in the era before modern antiretroviral therapy. PMID:25892019

  7. Long-term Outcomes of Cytomegalovirus Retinitis in the Era of Modern Antiretroviral Therapy: Results from a United States Cohort.

    PubMed

    Jabs, Douglas A; Ahuja, Alka; Van Natta, Mark L; Lyon, Alice T; Yeh, Steven; Danis, Ronald

    2015-07-01

    To describe the long-term outcomes of patients with cytomegalovirus (CMV) retinitis and AIDS in the modern era of combination antiretroviral therapy. Prospective, observational cohort study. Patients with AIDS and CMV retinitis. Immune recovery, defined as a CD4+ T-cell count >100 cells/μl for ≥3 months. Mortality, visual impairment (visual acuity <20/40), and blindness (visual acuity ≤20/200) on logarithmic visual acuity charts and loss of visual field on quantitative Goldmann perimetry. Patients without immune recovery had a mortality of 44.4/100 person-years (PYs) and a median survival of 13.5 months after the diagnosis of CMV retinitis, whereas those with immune recovery had a mortality of 2.7/100 PYs (P < 0.001) and an estimated median survival of 27.0 years after the diagnosis of CMV retinitis. The rates of bilateral visual impairment and blindness were 0.9 and 0.4/100 PYs, respectively, and were similar between those with and without immune recovery. Among those with immune recovery, the rate of visual field loss was approximately 1% of the normal field per year, whereas among those without immune recovery it was approximately 7% of the normal field per year. Among persons with CMV retinitis and AIDS, if there is immune recovery, long-term survival is likely, whereas if there is no immune recovery, the mortality rate is substantial. Although higher than the rates in the population not infected by human immunodeficiency virus, the rates of bilateral visual impairment and blindness are low, especially when compared with rates in the era before modern antiretroviral therapy. Copyright © 2015 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  8. NOx Emissions Characteristics and Correlation Equations of Two P and W's Axially Staged Sector Combustors Developed Under NASA Environmentally Responsible Aviation (ERA) Project

    NASA Technical Reports Server (NTRS)

    He, Zhuohui J.

    2017-01-01

    Two P&W (Pratt & Whitney)'s axially staged sector combustors have been developed under NASA's Environmentally Responsible Aviation (ERA) project. One combustor was developed under ERA Phase I, and the other was developed under ERA Phase II. Nitrogen oxides (NOx) emissions characteristics and correlation equations for these two sector combustors are reported in this article. The Phase I design was to optimize the NOx emissions reduction potential, while the Phase II design was more practical and robust. Multiple injection points and fuel staging strategies are used in the combustor design. Pilot-stage injectors are located on the front dome plate of the combustor, and main-stage injectors are positioned on the top and bottom (Phase I) or on the top only (Phase II) of the combustor liners downstream. Low power configuration uses only pilot-stage injectors. Main-stage injectors are added to high power configuration to help distribute fuel more evenly and achieve lean burn throughout the combustor yielding very low NOx emissions. The ICAO (International Civil Aviation Organization) landing-takeoff NOx emissions are verified to be 88 percent (Phase I) and 76 percent (Phase II) under the ICAO CAEP/6 (Committee on Aviation Environmental Protection 6th Meeting) standard, exceeding the ERA project goal of 75 percent reduction, and the combustors proved to have stable combustion with room to maneuver on fuel flow splits for operability.

  9. Oxide_Oxide Ceramic Matrix Composite (CMC) Exhaust Mixer Development in the NASA Environmentally Responsible Aviation (ERA) Project

    NASA Technical Reports Server (NTRS)

    Kiser, James D.; Bansal, Narottam P.; Szelagowski, J.; Sokhey, J.; Heffernan, T.; Clegg, J.; Pierluissi, A.; Riedell, J.; Atmur, S.; Wyen, T.; hide

    2015-01-01

    Rolls-Royce North American Technologies, Inc. (LibertyWorksLW) began considering the development of CMC exhaust forced mixers in 2008, as a means of obtaining reduced weight and hotter operating temperature capability, while minimizing shape distortion during operation, which would improve mixing efficiency and reduce fuel burn. Increased component durability, enhanced ability to fabricate complex-shaped components, and engine noise reduction are other potential advantages of CMC mixers (compared to metallic mixers). In 2010, NASA was pursuing the reduction of NOx emissions, fuel burn, and noise from turbine engines in Phase I of the Environmentally Responsible Aviation (ERA) Project. ERA subtasks, including those focused on CMC components, were formulated with the goal of maturing technology from proof of concept validation (TRL 3) to a systemsubsystem or prototype demonstration in a relevant environment (TRL 6). In April 2010, the NASA Glenn Research Center (GRC) and LibertyWorks jointly initiated a CMC Exhaust System Validation Program within the ERA Project, teaming on CMC exhaust mixer development for subsonic jet engines capable of operating with increased performance. Our initial focus was on designing, fabricating, and characterizing the thrust and acoustic performance of a roughly quarter-scale 16-lobe oxide oxide CMC mixer and tail cone along with a conventional low bypass exhaust nozzle. Support Services, LLC (Allendale, MI) and ATK COI Ceramics, Inc. (COIC, in San Diego, CA) supported the design of a subscale nozzle assembly that consisted of an oxide oxide CMC mixer and center body, with each component mounted on a metallic attachment ring. That design was based upon the operating conditions a mixer would experience in a turbofan engine. Validation of the aerodynamic and acoustic performance of the subscale mixer via testing and the achievement of TRL 4 encouraged the NASALWCOIC team to move to the next phase where a full scale CMC mixer sized for a RR

  10. Risk of second malignancies in patients with early-stage classical Hodgkin's lymphoma treated in a modern era.

    PubMed

    LeMieux, Melissa H; Solanki, Abhishek A; Mahmood, Usama; Chmura, Steven J; Koshy, Matthew

    2015-04-01

    Second malignancies remain an issue affecting morbidity and mortality in long-term survivors of early stage Hodgkin's lymphoma (HL). We undertook this study to determine if treatment in the modern era resulted in decreased second malignancies. Patients diagnosed with stage I-II cHL between 1988 and 2009 who received radiation therapy (RT) were selected from the Surveillance, Epidemiology, and End Results (SEER) database. Freedom from second malignancy (FFSM) was estimated using the Kaplan-Meier method. Univariate analysis (UVA) was performed using the Log-Rank test, and included age, gender, year of diagnosis, and stage. Multivariable analysis (MVA) was performed using Cox Proportional Hazards modeling. The study cohort included 8807 patients. The median age at diagnosis was 32 years (range: 2-85). The majority of patients had stage II disease (n = 6044, 69%), 597 (7%) had extranodal involvement (ENI), and 1925 (22%) had B symptoms. Median follow-up for the entire cohort was 7.2 years (range: 0-22). Five hundred twenty-three (6%) patients developed a second malignancy. Median latency to second malignancy was 5.8 years (range: 0.1-21.5). Of the 523 patients that developed a second malignancy, 228 (44%) occurred in the first 5 years, 139 (27%) were diagnosed between years 5-10, and 156 (30%) beyond 10 years. The 10 year FFSM for patients treated between 1988 and 1999 was 93.0% versus 95.1% for patients treated between 2000 and 2009 (P = 0.04), On MVA, treatment between 2000 and 2009 was associated with a HR for second malignancy of 0.77 (95% Confidence Interval: 0.62-0.96, P = 0.02) compared to the treatment between 1988 and 1999. Our analysis suggests that in patients treated with RT for stage I or II cHL, treatment prior to 2000 had a slightly higher risk of second malignancy compared to treatment in 2000 and later. Further studies, with longer follow-up of patients treated in the modern era are needed to confirm these findings. © 2015 The Authors. Cancer Medicine

  11. Comparisons of the tropospheric specific humidity from GPS radio occultations with ERA-Interim, NASA MERRA, and AIRS data

    NASA Astrophysics Data System (ADS)

    Vergados, Panagiotis; Mannucci, Anthony J.; Ao, Chi O.; Verkhoglyadova, Olga; Iijima, Byron

    2018-03-01

    We construct a 9-year data record (2007-2015) of the tropospheric specific humidity using Global Positioning System radio occultation (GPS RO) observations from the Constellation Observing System for Meteorology, Ionosphere, and Climate (COSMIC) mission. This record covers the ±40° latitude belt and includes estimates of the zonally averaged monthly mean specific humidity from 700 up to 400 hPa. It includes three major climate zones: (a) the deep tropics (±15°), (b) the trade winds belts (±15-30°), and (c) the subtropics (±30-40°). We find that the RO observations agree very well with the European Centre for Medium-Range Weather Forecasts Re-Analysis Interim (ERA-Interim), the Modern-Era Retrospective Analysis for Research and Applications (MERRA), and the Atmospheric Infrared Sounder (AIRS) by capturing similar magnitudes and patterns of variability in the monthly zonal mean specific humidity and interannual anomaly over annual and interannual timescales. The JPL and UCAR specific humidity climatologies differ by less than 15 % (depending on location and pressure level), primarily due to differences in the retrieved refractivity. In the middle-to-upper troposphere, in all climate zones, JPL is the wettest of all data sets, AIRS is the driest of all data sets, and UCAR, ERA-Interim, and MERRA are in very good agreement, lying between the JPL and AIRS climatologies. In the lower-to-middle troposphere, we present a complex behavior of discrepancies, and we speculate that this might be due to convection and entrainment. Conclusively, the RO observations could potentially be used as a climate variable, but more thorough analysis is required to assess the structural uncertainty between centers and its origin.

  12. Modernization of the NASA IRTF Telescope Control System

    NASA Astrophysics Data System (ADS)

    Pilger, Eric J.; Harwood, James V.; Onaka, Peter M.

    1994-06-01

    We describe the ongoing modernization of the NASA IR Telescope Facility Telescope Control System. A major mandate of this project is to keep the telescope available for observations throughout. Therefore, we have developed an incremental plan that will allow us to replace components of the software and hardware without shutting down the system. The current system, running under FORTH on a DEC LSI 11/23 minicomputer interfaced to a Bus and boards developed in house, will be replaced with a combination of a Sun SPARCstation running SunOS, a MicroSPARC based Single Board Computer running LynxOS, and various intelligent VME based peripheral cards. The software is based on a design philosophy originally developed by Pat Wallace for use on the Anglo Australian Telescope. This philosophy has gained wide acceptance, and is currently used in a number of observatories around the world. A key element of this philosophy is the division of the TCS into `Virtual' and `Real' parts. This will allow us to replace the higher level functions of the TCS with software running on the Sun, while still relying on the LSI 11/23 for performance of the lower level functions. Eventual transfer of lower level functions to the MicroSPARC system will then proceed incrementally through use of a Q-Bus to VME-Bus converter.

  13. The NASA modern technology rotors program

    NASA Technical Reports Server (NTRS)

    Watts, M. E.; Cross, J. L.

    1986-01-01

    Existing data bases regarding helicopters are based on work conducted on 'old-technology' rotor systems. The Modern Technology Rotors (MTR) Program is to provide extensive data bases on rotor systems using present and emerging technology. The MTR is concerned with modern, four-bladed, rotor systems presently being manufactured or under development. Aspects of MTR philosophy are considered along with instrumentation, the MTR test program, the BV 360 Rotor, and the UH-60 Black Hawk. The program phases include computer modelling, shake test, model-scale test, minimally instrumented flight test, extensively pressure-instrumented-blade flight test, and full-scale wind tunnel test.

  14. Recent Reanalysis Activities at ECMWF: Results from ERA-20C and Plans for ERA5

    NASA Astrophysics Data System (ADS)

    Dragani, R.; Hersbach, H.; Poli, P.; Pebeuy, C.; Hirahara, S.; Simmons, A.; Dee, D.

    2015-12-01

    This presentation will provide an overview of the most recent reanalysis activities performed at the European Centre for Medium-Range Weather Forecasts (ECMWF). A pilot reanalysis of the 20th-century (ERA-20C) has recently been completed. Funded through the European FP7 collaborative project ERA-CLIM, ERA-20C is part of a suite of experiments that also includes a model-only integration (ERA-20CM) and a land-surface reanalysis (ERA-20CL). Its data assimilation system is constrained by only surface observations obtained from ISPD (3.2.6) and ICOADS (2.5.1). Surface boundary conditions are provided by the Hadley Centre (HadISST2.1.0.0) and radiative forcing follows CMIP5 recommended data sets. First-guess uncertainty estimates are based on a 10-member ensemble of Data Assimilations, ERA-20C ensemble, run prior to ERA-20C using ten SST and sea-ice realizations from the Hadley Centre. In November 2014, the European Commission entrusted ECMWF to run on its behalf the Copernicus Climate Change Service (C3S) aiming at producing quality-assured information about the past, current and future states of the climate at both European and global scales. Reanalysis will be one of the main components of the C3S portfolio and the first one to be produced is a global modern era reanalysis (ERA5) covering the period from 1979 onwards. Based on a recent version of the ECMWF data assimilation system, ERA5 will replace the widely used ERA-Interim dataset. This new production will benefit from a much improved model, and better characterized and exploited observations compared to its predecessor. The first part of the presentation will focus on the ERA-20C production, provide an overview of its main characteristics and discuss some of the key results from its assessment. The second part of the talk will give an overview of ERA5, and briefly discuss some of its challenges.

  15. Status of ERA Vehicle System Integration Technology Demonstrators

    NASA Technical Reports Server (NTRS)

    Flamm, Jeffrey D.; Fernandez, Hamilton; Khorrami, Mehdi; James, Kevin D.; Thomas, Russell

    2015-01-01

    The Environmentally Responsible Aviation (ERA) Project within the Integrated Systems Research Program (ISRP) of the NASA Aeronautics Research Mission Directorate (ARMD) has the responsibility to explore and document the feasibility, benefits, and technical risk of air vehicle concepts and enabling technologies that will reduce the impact of aviation on the environment. The primary goal of the ERA Project is to select air vehicle concepts and technologies that can simultaneously reduce fuel burn, noise, and emissions. In addition, the ERA Project will identify and mitigate technical risk and transfer knowledge to the aeronautics community at large so that new technologies and vehicle concepts can be incorporated into the future design of aircraft.

  16. Conceptual Design and Cost Estimate of a Subsonic NASA Testbed Vehicle (NTV) for Aeronautics Research

    NASA Technical Reports Server (NTRS)

    Nickol, Craig L.; Frederic, Peter

    2013-01-01

    A conceptual design and cost estimate for a subsonic flight research vehicle designed to support NASA's Environmentally Responsible Aviation (ERA) project goals is presented. To investigate the technical and economic feasibility of modifying an existing aircraft, a highly modified Boeing 717 was developed for maturation of technologies supporting the three ERA project goals of reduced fuel burn, noise, and emissions. This modified 717 utilizes midfuselage mounted modern high bypass ratio engines in conjunction with engine exhaust shielding structures to provide a low noise testbed. The testbed also integrates a natural laminar flow wing section and active flow control for the vertical tail. An eight year program plan was created to incrementally modify and test the vehicle, enabling the suite of technology benefits to be isolated and quantified. Based on the conceptual design and programmatic plan for this testbed vehicle, a full cost estimate of $526M was developed, representing then-year dollars at a 50% confidence level.

  17. NASA Team Collaboration Pilot: Enabling NASA's Virtual Teams

    NASA Technical Reports Server (NTRS)

    Prahst, Steve

    2003-01-01

    Most NASA projects and work activities are accomplished by teams of people. These teams are often geographically distributed - across NASA centers and NASA external partners, both domestic and international. NASA "virtual" teams are stressed by the challenge of getting team work done - across geographic boundaries and time zones. To get distributed work done, teams rely on established methods - travel, telephones, Video Teleconferencing (NASA VITS), and email. Time is our most critical resource - and team members are hindered by the overhead of travel and the difficulties of coordinating work across their virtual teams. Modern, Internet based team collaboration tools offer the potential to dramatically improve the ability of virtual teams to get distributed work done.

  18. Data Recovery Effort of Nimbus Era Observations by the NASA GES DISC

    NASA Technical Reports Server (NTRS)

    Johnson, James; Esfandiari, Ed; Zamkoff, Emily; Gerasimov, Irina; Al-Jazrawi, Atheer; Alcott, Gary

    2017-01-01

    NASA launched seven Nimbus meteorological satellites in the 1960s and 70s. These satellites carried instruments for making observations of the Earth in the visible, infrared, ultraviolet, and microwave wavelengths. The original data archive consisted of a combination of magnetic tapes and various film media. As these media are well past their expected end of life, the valuable data they contain are now being migrated to the GES DISC modern online archive. The process involves recovering the digital data files from the tapes as well as scanning images of the data from film strips. This presentation will address the status and challenges of recovering the Nimbus data. The old data products were written on now obsolete hardware systems and outdated file formats. They lack any metadata standards and each product is often written in its own proprietary file structure. This requires creating metadata by reading the contents of the old data files. The job is tedious and laborious, as documentation may be incomplete, data files and tapes are sometimes corrupted, or were improperly copied at the time they were created.

  19. NASA astronomical findings highlighted on This Week @NASA – January 8, 2016

    NASA Image and Video Library

    2016-01-08

    New NASA astrophysics findings were highlighted at the 227th American Astronomical Society meeting, Jan. 4-8 in Kissimmee, Florida. The findings, which ranged from runaway stars to a burping galaxy, were made with the help of several NASA observation instruments, including the Spitzer Space Telescope, the Wide-field Infrared Survey Explorer, the Chandra X-ray Observatory, the Nuclear Spectroscopic Telescope Array and others. Also, Next space station crew preparing for mission, Economical new era of aviation, A new level of coral reef studies and more!

  20. Exploring and Analyzing Climate Variations Online by Using NASA MERRA-2 Data at GES DISC

    NASA Technical Reports Server (NTRS)

    Shen, Suhung; Ostrenga, Dana M.; Vollmer, Bruce E.; Kempler, Steven J.

    2016-01-01

    NASA Giovanni (Goddard Interactive Online Visualization ANd aNalysis Infrastructure) (http:giovanni.sci.gsfc.nasa.govgiovanni) is a web-based data visualization and analysis system developed by the Goddard Earth Sciences Data and Information Services Center (GES DISC). Current data analysis functions include Lat-Lon map, time series, scatter plot, correlation map, difference, cross-section, vertical profile, and animation etc. The system enables basic statistical analysis and comparisons of multiple variables. This web-based tool facilitates data discovery, exploration and analysis of large amount of global and regional remote sensing and model data sets from a number of NASA data centers. Long term global assimilated atmospheric, land, and ocean data have been integrated into the system that enables quick exploration and analysis of climate data without downloading, preprocessing, and learning data. Example data include climate reanalysis data from NASA Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2) which provides data beginning in 1980 to present; land data from NASA Global Land Data Assimilation System (GLDAS), which assimilates data from 1948 to 2012; as well as ocean biological data from NASA Ocean Biogeochemical Model (NOBM), which provides data from 1998 to 2012. This presentation, using surface air temperature, precipitation, ozone, and aerosol, etc. from MERRA-2, demonstrates climate variation analysis with Giovanni at selected regions.

  1. NASA's Long-range Technology Goals

    NASA Technical Reports Server (NTRS)

    1990-01-01

    This document is part of the Final Report performed under contract NASW-3864, titled "NASA's Long-Range Technology Goals". The objectives of the effort were: To identify technologies whose development falls within NASA's capability and purview, and which have high potential for leapfrog advances in the national industrial posture in the 2005-2010 era. To define which of these technologies can also enable quantum jumps in the national space program. To assess mechanisms of interaction between NASA and industry constituencies for realizing the leapfrog technologies. This Volume details the findings pertaining to the advanced space-enabling technologies.

  2. NASA Space Biology Plant Research for 2010-2020

    NASA Technical Reports Server (NTRS)

    Levine, H. G.; Tomko, D. L.; Porterfield, D. M.

    2012-01-01

    The U.S. National Research Council (NRC) recently published "Recapturing a Future for Space Exploration: Life and Physical Sciences Research for a New Era" (http://www.nap.edu/catalog.php?record id=13048), and NASA completed a Space Biology Science Plan to develop a strategy for implementing its recommendations ( http://www.nasa.gov/exploration/library/esmd documents.html). The most important recommendations of the NRC report on plant biology in space were that NASA should: (1) investigate the roles of microbial-plant systems in long-term bioregenerative life support systems, and (2) establish a robust spaceflight program of research analyzing plant growth and physiological responses to the multiple stimuli encountered in spaceflight environments. These efforts should take advantage of recently emerged analytical technologies (genomics, transcriptomics, proteomics, metabolomics) and apply modern cellular and molecular approaches in the development of a vigorous flight-based and ground-based research program. This talk will describe NASA's strategy and plans for implementing these NRC Plant Space Biology recommendations. New research capabilities for Plant Biology, optimized by providing state-of-the-art automated technology and analytical techniques to maximize scientific return, will be described. Flight experiments will use the most appropriate platform to achieve science results (e.g., ISS, free flyers, sub-orbital flights) and NASA will work closely with its international partners and other U.S. agencies to achieve its objectives. One of NASA's highest priorities in Space Biology is the development research capabilities for use on the International Space Station and other flight platforms for studying multiple generations of large plants. NASA will issue recurring NASA Research Announcements (NRAs) that include a rapid turn-around model to more fully engage the biology community in designing experiments to respond to the NRC recommendations. In doing so, NASA

  3. Survival Benefit of Lung Transplantation in the Modern Era of Lung Allocation.

    PubMed

    Vock, David M; Durheim, Michael T; Tsuang, Wayne M; Finlen Copeland, C Ashley; Tsiatis, Anastasios A; Davidian, Marie; Neely, Megan L; Lederer, David J; Palmer, Scott M

    2017-02-01

    Lung transplantation is an accepted and increasingly employed treatment for advanced lung diseases, but the anticipated survival benefit of lung transplantation is poorly understood. To determine whether and for which patients lung transplantation confers a survival benefit in the modern era of U.S. lung allocation. Data on 13,040 adults listed for lung transplantation between May 2005 and September 2011 were obtained from the United Network for Organ Sharing. A structural nested accelerated failure time model was used to model the survival benefit of lung transplantation over time. The effects of patient, donor, and transplant center characteristics on the relative survival benefit of transplantation were examined. Overall, 73.8% of transplant recipients were predicted to achieve a 2-year survival benefit with lung transplantation. The survival benefit of transplantation varied by native disease group (P = 0.062), with 2-year expected benefit in 39.2 and 98.9% of transplants occurring in those with obstructive lung disease and cystic fibrosis, respectively, and by lung allocation score at the time of transplantation (P < 0.001), with net 2-year benefit in only 6.8% of transplants occurring for lung allocation score less than 32.5 and in 99.9% of transplants for lung allocation score exceeding 40. A majority of adults undergoing transplantation experience a survival benefit, with the greatest potential benefit in those with higher lung allocation scores or restrictive native lung disease or cystic fibrosis. These results provide novel information to assess the expected benefit of lung transplantation at an individual level and to enhance lung allocation policy.

  4. Progressive Era Industry and Its Legacy: Essays and Lesson Plans for Teaching Industrial History of the Progressive Era.

    ERIC Educational Resources Information Center

    Murray, William J., Ed.

    The Progressive Era, roughly the period between the Spanish American War and the U.S. entry into World War I, was a period of transformation, a time when the United States ceased being predominantly an agricultural economy with a minor industrial base and became predominantly a modern industrialized nation. These essays and lesson plans, the…

  5. Psychiatry during the Nazi era: ethical lessons for the modern professional

    PubMed Central

    Strous, Rael D

    2007-01-01

    For the first time in history, psychiatrists during the Nazi era sought to systematically exterminate their patients. However, little has been published from this dark period analyzing what may be learned for clinical and research psychiatry. At each stage in the murderous process lay a series of unethical and heinous practices, with many psychiatrists demonstrating a profound commitment to the atrocities, playing central, pivotal roles critical to the success of Nazi policy. Several misconceptions led to this misconduct, including allowing philosophical constructs to define clinical practice, focusing exclusively on preventative medicine, allowing political pressures to influence practice, blurring the roles of clinicians and researchers, and falsely believing that good science and good ethics always co-exist. Psychiatry during this period provides a most horrifying example of how science may be perverted by external forces. It thus becomes crucial to include the Nazi era psychiatry experience in ethics training as an example of proper practice gone awry. PMID:17326822

  6. Overview of ERA Integrated Technology Demonstration (ITD) 51A Ultra-High Bypass (UHB) Integration for Hybrid Wing Body (HWB)

    NASA Technical Reports Server (NTRS)

    Flamm, Jeffrey D.; James, Kevin D.; Bonet, John T.

    2016-01-01

    The NASA Environmentally Responsible Aircraft Project (ERA) was a ve year project broken into two phases. In phase II, high N+2 Technical Readiness Level demonstrations were grouped into Integrated Technology Demonstrations (ITD). This paper describes the work done on ITD-51A: the Vehicle Systems Integration, Engine Airframe Integration Demonstration. Refinement of a Hybrid Wing Body (HWB) aircraft from the possible candidates developed in ERA Phase I was continued. Scaled powered, and unpowered wind- tunnel testing, with and without acoustics, in the NASA LARC 14- by 22-foot Subsonic Tunnel, the NASA ARC Unitary Plan Wind Tunnel, and the 40- by 80-foot test section of the National Full-Scale Aerodynamics Complex (NFAC) in conjunction with very closely coupled Computational Fluid Dynamics was used to demonstrate the fuel burn and acoustic milestone targets of the ERA Project.

  7. Survival Benefit of Lung Transplantation in the Modern Era of Lung Allocation

    PubMed Central

    Tsuang, Wayne M.; Copeland, C. Ashley Finlen; Tsiatis, Anastasios A.; Davidian, Marie; Neely, Megan L.; Lederer, David J.; Palmer, Scott M.

    2017-01-01

    Rationale: Lung transplantation is an accepted and increasingly employed treatment for advanced lung diseases, but the anticipated survival benefit of lung transplantation is poorly understood. Objectives: To determine whether and for which patients lung transplantation confers a survival benefit in the modern era of U.S. lung allocation. Methods: Data on 13,040 adults listed for lung transplantation between May 2005 and September 2011 were obtained from the United Network for Organ Sharing. A structural nested accelerated failure time model was used to model the survival benefit of lung transplantation over time. The effects of patient, donor, and transplant center characteristics on the relative survival benefit of transplantation were examined. Measurements and Main Results: Overall, 73.8% of transplant recipients were predicted to achieve a 2-year survival benefit with lung transplantation. The survival benefit of transplantation varied by native disease group (P = 0.062), with 2-year expected benefit in 39.2 and 98.9% of transplants occurring in those with obstructive lung disease and cystic fibrosis, respectively, and by lung allocation score at the time of transplantation (P < 0.001), with net 2-year benefit in only 6.8% of transplants occurring for lung allocation score less than 32.5 and in 99.9% of transplants for lung allocation score exceeding 40. Conclusions: A majority of adults undergoing transplantation experience a survival benefit, with the greatest potential benefit in those with higher lung allocation scores or restrictive native lung disease or cystic fibrosis. These results provide novel information to assess the expected benefit of lung transplantation at an individual level and to enhance lung allocation policy. PMID:27779905

  8. White House Forum on Modernizing Government

    NASA Image and Video Library

    2010-01-14

    NASA Deputy Administrator Lori Garver, left, talks with Deputy Secretary of Education Tony Miller prior to the start of the White House Forum on Modernizing Government held Thursday, Jan. 14, 2010 at the Old Executive Office Building in Washington. As part of his commitment to change how business is done in Washington and instill a new sense of responsibility for taxpayer dollars, the President welcomed more than 50 of the country’s top CEOs to the White House Forum on Modernizing Government. Photo Credit: (NASA/Bill Ingalls)

  9. Phylogenetics of modern birds in the era of genomics

    PubMed Central

    Edwards, Scott V; Bryan Jennings, W; Shedlock, Andrew M

    2005-01-01

    In the 14 years since the first higher-level bird phylogenies based on DNA sequence data, avian phylogenetics has witnessed the advent and maturation of the genomics era, the completion of the chicken genome and a suite of technologies that promise to add considerably to the agenda of avian phylogenetics. In this review, we summarize current approaches and data characteristics of recent higher-level bird studies and suggest a number of as yet untested molecular and analytical approaches for the unfolding tree of life for birds. A variety of comparative genomics strategies, including adoption of objective quality scores for sequence data, analysis of contiguous DNA sequences provided by large-insert genomic libraries, and the systematic use of retroposon insertions and other rare genomic changes all promise an integrated phylogenetics that is solidly grounded in genome evolution. The avian genome is an excellent testing ground for such approaches because of the more balanced representation of single-copy and repetitive DNA regions than in mammals. Although comparative genomics has a number of obvious uses in avian phylogenetics, its application to large numbers of taxa poses a number of methodological and infrastructural challenges, and can be greatly facilitated by a ‘community genomics’ approach in which the modest sequencing throughputs of single PI laboratories are pooled to produce larger, complementary datasets. Although the polymerase chain reaction era of avian phylogenetics is far from complete, the comparative genomics era—with its ability to vastly increase the number and type of molecular characters and to provide a genomic context for these characters—will usher in a host of new perspectives and opportunities for integrating genome evolution and avian phylogenetics. PMID:16024355

  10. Current and Future Perspectives of Aerosol Research at NASA Goddard Space Flight Center

    NASA Technical Reports Server (NTRS)

    Matsui, Toshihisa; Ichoku, Charles; Randles, Cynthia; Yuan, Tianle; Da Silva, Arlindo M.; Colarco, Peter R.; Kim, Dongchul; Levy, Robert; Sayer, Andrew; Chin, Mian; hide

    2014-01-01

    Aerosols are tiny atmospheric particles that are emitted from various natural and anthropogenic sources. They affect climate through direct and indirect interactions with solar and thermal radiation, clouds, and atmospheric circulation (Solomon et al. 2007). The launch of a variety of sophisticated satellite-based observing systems aboard the Terra, Aqua, Aura, SeaWiFS (see appendix for all acronym expansions), CALIPSO, and other satellites in the late 1990s to mid-2000s through the NASA EOS and other U.S. and non-U.S. programs ushered in a golden era in aerosol research. NASA has been a leader in providing global aerosol characterizations through observations from satellites, ground networks, and field campaigns, as well as from global and regional modeling. AeroCenter (http://aerocenter.gsfc.nasa.gov/), which was formed in 2002 to address the many facets of aerosol research in a collaborative manner, is an interdisciplinary union of researchers (200 members) at NASA GSFC and other nearby institutions, including NOAA, several universities, and research laboratories. AeroCenter hosts a web-accessible regular seminar series and an annual meeting to present up-to-date aerosol research, including measurement techniques; remote sensing algorithms; modeling development; field campaigns; and aerosol interactions with radiation, clouds, precipitation, climate, biosphere, atmospheric chemistry, air quality, and human health. The 2013 annual meeting was held at the NASA GSFC Visitor Center on 31 May 2013, which coincided with the seventh anniversary of the passing of Yoram Kaufman, a modern pioneer in satellite-based aerosol science and the founder of AeroCenter. The central theme of this year's meeting was "current and future perspectives" of NASA's aerosol science and satellite missions.

  11. Let's Get into Some Scijinks! Lessons from Modernizing a Classic NOAA/NASA Kids' Weather Website

    NASA Astrophysics Data System (ADS)

    Leon, N.; Kasprak, A. H.; Mansfield, K. J.; Novati, A.; Gaches, L.; Karlson, D.

    2014-12-01

    SciJinks.gov—short for Science Hijinks—is a joint NOAA and NASA website that has been in operation for a decade. Filled with information about weather, Earth science, and satellite meteorology, it has always been a helpful resource for students and educators in and outside of the classroom. Geared toward upper middle school and early high school students, we replace around 20% of our audience each year. That means it is imperative to keep the site properly geared toward the needs of a rapidly changing group of students. Our team has recently redesigned SciJinks.gov to be mobile-friendly, modern looking, and teen-friendly. Here, we discuss our strategies and rational for this redesign and highlight the many exciting benefits to this newly imagined weather-adventure website.

  12. GIS application on modern Mexico

    NASA Astrophysics Data System (ADS)

    Prakash, Bharath

    This is a GIS based tool for showcasing the history of modern Mexico starting from the post-colonial era to the elections of 2012. The tool is developed using simple language and is flexible so as to allow for future enhancements. The application consists of numerous images and textual information, and also some links which can be used by primary and high school students to understand the history of modern Mexico, and also by tourists to look for all the international airports and United States of America consulates. This software depicts the aftermaths of the Colonial Era or the Spanish rule of Mexico. It covers various topics like the wars, politics, important personalities, drug cartels and violence. All these events are shown on GIS (Geographic information Science) maps. The software can be customized according to the user requirements and is developed using JAVA and GIS technology. The user interface is created using JAVA and MOJO which contributes to effective learning and understanding of the concepts with ease. Some of the user interface features provided in this tool includes zoom-in, zoom-out, legend editing, location identifier, print command, adding a layer and numerous menu items.

  13. Evaluation of the Ozone Fields in NASA's MERRA-2 Reanalysis

    NASA Technical Reports Server (NTRS)

    Wargan, Krzysztof; Labow, Gordon; Frith, Stacey; Pawson, Steven; Livesey, Nathaniel; Partyka, Gary

    2017-01-01

    We describe and assess the quality of the assimilated ozone product from the Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2) produced at NASAs Global Modeling and Assimilation Office (GMAO) spanning the time period from 1980 to present. MERRA-2 assimilates partial column ozone retrievals from a series of Solar Backscatter Ultraviolet (SBUV) radiometers on NASA and NOAA spacecraft between January 1980 and September 2004; starting in October 2004 retrieved ozone profiles from the Microwave Limb Sounder (MLS) and total column ozone from the Ozone Monitoring Instrument on NASAs EOS Aura satellite are assimilated. We compare the MERRA-2 ozone with independent satellite and ozonesonde data focusing on the representation of the spatial and temporal variability of stratospheric and upper tropospheric ozone and on implications of the change in the observing system from SBUV to EOS Aura. The comparisons show agreement within 10 (standard deviation of the difference) between MERRA-2 profiles and independent satellite data in most of the stratosphere. The agreement improves after 2004 when EOS Aura data are assimilated. The standard deviation of the differences between the lower stratospheric and upper tropospheric MERRA-2 ozone and ozonesondes is 11.2 and 24.5, respectively, with correlations of 0.8 and above, indicative of a realistic representation of the near-tropopause ozone variability in MERRA-2. The agreement improves significantly in the EOS Aura period, however MERRA-2 is biased low in the upper troposphere with respect to the ozonesondes. Caution is recommended when using MERRA-2 ozone for decadal changes and trend studies.

  14. Evaluation of the Ozone Fields in NASA's MERRA-2 Reanalysis.

    PubMed

    Wargan, Krzysztof; Labow, Gordon; Frith, Stacey; Pawson, Steven; Livesey, Nathaniel; Partyka, Gary

    2017-04-01

    We describe and assess the quality of the assimilated ozone product from the Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2) produced at NASA's Global Modeling and Assimilation Office (GMAO) spanning the time period from 1980 to present. MERRA-2 assimilates partial column ozone retrievals from a series of Solar Backscatter Ultraviolet (SBUV) radiometers on NASA and NOAA spacecraft between January 1980 and September 2004; starting in October 2004 retrieved ozone profiles from the Microwave Limb Sounder (MLS) and total column ozone from the Ozone Monitoring Instrument on NASA's EOS Aura satellite are assimilated. We compare the MERRA-2 ozone with independent satellite and ozonesonde data focusing on the representation of the spatial and temporal variability of stratospheric and upper tropospheric ozone and on implications of the change in the observing system from SBUV to EOS Aura. The comparisons show agreement within 10 % (standard deviation of the difference) between MERRA-2 profiles and independent satellite data in most of the stratosphere. The agreement improves after 2004 when EOS Aura data are assimilated. The standard deviation of the differences between the lower stratospheric and upper tropospheric MERRA-2 ozone and ozonesondes is 11.2 % and 24.5 %, respectively, with correlations of 0.8 and above, indicative of a realistic representation of the near-tropopause ozone variability in MERRA-2. The agreement improves significantly in the EOS Aura period, however MERRA-2 is biased low in the upper troposphere with respect to the ozonesondes. Caution is recommended when using MERRA-2 ozone for decadal changes and trend studies.

  15. NASA Space Technology Roadmaps and Priorities: Restoring NASA's Technological Edge and Paving the Way for a New Era in Space

    NASA Technical Reports Server (NTRS)

    2012-01-01

    Success in executing future NASA space missions will depend on advanced technology developments that should already be underway. It has been years since NASA has had a vigorous, broad-based program in advanced space technology development, and NASA's technology base is largely depleted. As noted in a recent National Research Council report on the U.S. civil space program: Future U.S. leadership in space requires a foundation of sustained technology advances that can enable the development of more capable, reliable, and lower-cost spacecraft and launch vehicles to achieve space program goals. A strong advanced technology development foundation is needed also to enhance technology readiness of new missions, mitigate their technological risks, improve the quality of cost estimates, and thereby contribute to better overall mission cost management. Yet financial support for this technology base has eroded over the years. The United States is now living on the innovation funded in the past and has an obligation to replenish this foundational element. NASA has developed a draft set of technology roadmaps to guide the development of space technologies under the leadership of the NASA Office of the Chief Technologist. The NRC appointed the Steering Committee for NASA Technology Roadmaps and six panels to evaluate the draft roadmaps, recommend improvements, and prioritize the technologies within each and among all of the technology areas as NASA finalizes the roadmaps. The steering committee is encouraged by the initiative NASA has taken through the Office of the Chief Technologist (OCT) to develop technology roadmaps and to seek input from the aerospace technical community with this study.

  16. The ERA-EDTA today and tomorrow: a progress document by the ERA-EDTA Council.

    PubMed

    Zoccali, Carmine; Arici, Mustafa; Blankestijn, Peter J; Bruchfeld, Annette; Capasso, Giovambattista; Fliser, Danilo; Fouque, Denis; Goumenos, Dimitrios; Ketteler, Markus; Malyszko, Jolanta; Massy, Ziad; Rychlík, Ivan; Spasovski, Goce

    2018-05-23

    Scientific societies are increasingly seen as central to the advancement of information sharing and collaboration among scientists and clinical investigators for the progress of medical research and the promotion of education, professional competence, integrity and quality studies. To more effectively serve the practicing nephrologists and investigators dedicated to renal science, the Council of the European Renal Association and European Dialysis and Transplantation Association (ERA-EDTA) reorganized and integrated the various activities of the society into two branches, the Clinical Nephrology Governance branch and the Renal Science branch. New affordable initiatives to promote research, education and professional development and to advocate for the recognition of chronic kidney disease as a major public health issue at the European level will be put in place and/or potentiated in the new organizational frame. Educational initiatives will be espoused to Continuous Professional Development and, starting from 2019, 14 Education & Continuous Professional Development courses will be held covering the full range of knowledge areas of modern nephrology. Consolidation and development is the short- and medium-term mantra of the ERA-EDTA. The society has a rich portfolio of successful activities and brilliant, creative scientists among its members. Integrating the various activities of the ERA-EDTA and treasuring the expertise and wisdom of its most accomplished members will facilitate collaborative research, education and its public impact at large.

  17. NASA Ames Research Center 60 MW Power Supply Modernization

    NASA Technical Reports Server (NTRS)

    Choy, Yuen Ching; Ilinets, Boris V.; Miller, Ted; Nagel, Kirsten (Technical Monitor)

    2001-01-01

    The NASA Ames Research Center 60 MW DC Power Supply was built in 1974 to provide controlled DC power for the Thermophysics Facility Arc Jet Laboratory. The Power Supply has gradually losing reliability due to outdated technology and component life limitation. NASA has decided to upgrade the existing rectifier modules with contemporary high-power electronics and control equipment. NASA plans to complete this project in 2001. This project includes a complete replacement of obsolete thyristor stacks in all six rectifier modules and rectifier bridge control system. High power water-cooled thyristors and freewheeling diodes will be used. The rating of each of the six modules will be 4000 A at 5500 V. The control firing angle signal will be sent from the Facility Control System to six modules via fiberoptic cable. The Power Supply control and monitoring system will include a Master PLC in the Facility building and a Slave PLC in each rectifier module. This system will also monitor each thyristor level in each stack and the auxiliary equipment.

  18. Evaluation of the Ozone Fields in NASA's MERRA-2 Reanalysis

    NASA Technical Reports Server (NTRS)

    Wargan, Krzysztof; Pawson, Steven; Labow, Gordon; Frith, Stacey M.; Livesey, Nathaniel; Partyka, Gary

    2017-01-01

    The assimilated ozone product from the Modern-Era Retrospective Analysis for Research and Applications, Version 2 (MERRA-2), produced at NASAs Global Modeling and Assimilation Office (GMAO) is summarized. The reanalysis begins in 1980 with the use of retrieved partial-column ozone concentrations from a series of Solar Backscatter Ultraviolet Radiometer (SBUV) instruments on NASA and NOAA spacecraft. Beginning in October 2004, retrieved ozone profiles from the Microwave Limb Sounder (MLS) and total column ozone from the Ozone Monitoring Instrument (OMI) on NASAs EOS Aura satellite are assimilated. While this change in data streams does lead to a discontinuity in the assimilated ozone fields in MERRA-2, making it not useful for studies in decadal (secular) trends in ozone, this choice was made to prioritize demonstrating the value NASAs high-quality research data in the reanalysis context. The MERRA-2 ozone is compared with independent satellite and ozonesonde data, focusing on the representation of the spatial and temporal variability of stratospheric and upper-tropospheric ozone. The comparisons show agreement within 10 (standard deviation of the difference) between MERRA-2 profiles and independent satellite data in most of the stratosphere. The agreement improves after 2004, when EOS Aura data are assimilated. The standard deviation of the differences between the lower-stratospheric and upper-tropospheric MERRA-2 ozone and ozonesondes is 11.2 and 24.5, respectively, with correlations of 0.8 and above. This is indicative of a realistic representation of the UTLS ozone variability in MERRA-2. After 2004, the upper tropospheric ozone in MERRA-2 shows a low bias compared to the sondes, but the covariance with independent observations is improved compared to earlier years. Case studies demonstrate the integrity of MERRA-2 analyses in representing important features such as tropopause folds.

  19. Modernization of US Nuclear Forces: Costs in Perspective

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tapia-Jimenez, D.

    This short research paper addresses two topics that have emerged in the debate about whether, when, and how to modernize U.S. nuclear forces.1 The first topic relates to the size and scale of the planned nuclear force, with some critics of the modernization plan arguing that the United States is simply replicating the Cold War force for a very different era. The second topic relates to the cost of the modernization effort, with some critics arguing that the cost is unaffordable.2 This paper begins with a review of the changes in the size and scale of U.S. nuclear forces sincemore » the Cold War. It then examines the expected costs of modernization in a comparative perspective.« less

  20. Application of Aura OMI L2G Products Compared with NASA MERRA-2 Assimilation

    NASA Technical Reports Server (NTRS)

    Zeng, Jian; Shen, Suhung; Wei, Jennifer; Johnson, James E.; Su, Jian; Meyer, David J.

    2018-01-01

    The Ozone Monitoring Instrument (OMI) is one of the instruments aboard NASA's Aura satellite. It measures ozone total column and vertical profile, aerosols, clouds, and trace gases including NO2, SO2, HCHO, BrO, and OClO using absorption in the ultraviolet electromagnetic spectrum (280 - 400 nm). OMI Level-2G (L2G) products are based on the pixel-level OMI granule satellite measurements stored within global 0.25 deg. X 0.25 deg. grids, therefore they conserve all the Level 2 (L2) spatial and temporal details for 24 hours of scientific data in one file. The second Modern-Era Retrospective analysis for Research and Applications (MERRA-2) is NASA's atmospheric reanalysis, using an upgraded version of Goddard Earth Observing System Model, version 5 (GEOS-5) data assimilation system. MERRA-2 includes aerosol data reanalysis and improved representations of stratospheric ozone, compared with its predecessor MERRA, in both instantaneous and time-averaged collections. It is found that simply comparing satellite Level-3 products might cause biases, due to lack of detailed temporal and original retrieval information. It is therefore preferable to inter-compare or implement satellite derived physical quantities directly with/to model assimilation with as high temporal and spatial resolutions as possible. This study will demonstrate utilization of OMI L2G daily aerosol and ozone products by comparing them with MERRA-2 hourly aerosol/ozone simulations, matched in both space and time aspects. Both OMI and MERRA-2 products are accessible online through NASA Goddard Earth Sciences Data Information Services Center (GES DISC, https://disc.gsfc.nasa.gov/).

  1. Environmentally Responsible Aviation (ERA) Project - N+2 Advanced Vehicle Concepts Study and Conceptual Design of Subscale Test Vehicle (STV) Final Report

    NASA Technical Reports Server (NTRS)

    Bonet, John T.; Schellenger, Harvey G.; Rawdon, Blaine K.; Elmer, Kevin R.; Wakayama, Sean R.; Brown, Derrell L.; Guo, Yueping

    2011-01-01

    NASA has set demanding goals for technology developments to meet national needs to improve fuel efficiency concurrent with improving the environment to enable air transportation growth. A figure shows NASA's subsonic transport system metrics. The results of Boeing ERA N+2 Advanced Vehicle Concept Study show that the Blended Wing Body (BWB) vehicle, with ultra high bypass propulsion systems have the potential to meet the combined NASA ERA N+2 goals. This study had 3 main activities. 1) The development of an advanced vehicle concepts that can meet the NASA system level metrics. 2) Identification of key enabling technologies and the development of technology roadmaps and maturation plans. 3) The development of a subscale test vehicle that can demonstrate and mature the key enabling technologies needed to meet the NASA system level metrics. Technology maturation plans are presented and include key performance parameters and technical performance measures. The plans describe the risks that will be reduced with technology development and the expected progression of technical maturity.

  2. Gravitational Physics: the birth of a new era

    NASA Astrophysics Data System (ADS)

    Sakellariadou, Mairi

    2017-11-01

    We live the golden age of cosmology, while the era of gravitational astronomy has finally begun. Still, fundamental puzzles remain. Standard cosmology is formulated within the framework of Einstein's General theory of Relativity. Notwithstanding, General Relativity is not adequate to explain the earliest stages of cosmic existence, and cannot provide an explanation for the Big Bang itself. Modern early universe cosmology is in need of a rigorous underpinning in Quantum Gravity.

  3. NASA support for commerce in space - Broadening opportunities

    NASA Technical Reports Server (NTRS)

    Stone, Barbara A.; Livingston, Candace D.

    1989-01-01

    The status of the NASA Office of Commercial Program's initiatives to implement the 1988 commercial space policy and expand industrial interest in the commercial development of space in the post-Challenger era is presented. Specific objectives have been developed to capture the drive and creativity of the private sector, for increasing NASA's effectiveness in conducting business with industrial firms, and impacting the commercial space market. An aggressive, comprehensive, and forward-looking program has been defined which provides the type of infrastructure and organization required to bring industry into the mainstream of space activities.

  4. GPM Ground Validation: Pre to Post-Launch Era

    NASA Astrophysics Data System (ADS)

    Petersen, Walt; Skofronick-Jackson, Gail; Huffman, George

    2015-04-01

    NASA GPM Ground Validation (GV) activities have transitioned from the pre to post-launch era. Prior to launch direct validation networks and associated partner institutions were identified world-wide, covering a plethora of precipitation regimes. In the U.S. direct GV efforts focused on use of new operational products such as the NOAA Multi-Radar Multi-Sensor suite (MRMS) for TRMM validation and GPM radiometer algorithm database development. In the post-launch, MRMS products including precipitation rate, accumulation, types and data quality are being routinely generated to facilitate statistical GV of instantaneous (e.g., Level II orbit) and merged (e.g., IMERG) GPM products. Toward assessing precipitation column impacts on product uncertainties, range-gate to pixel-level validation of both Dual-Frequency Precipitation Radar (DPR) and GPM microwave imager data are performed using GPM Validation Network (VN) ground radar and satellite data processing software. VN software ingests quality-controlled volumetric radar datasets and geo-matches those data to coincident DPR and radiometer level-II data. When combined MRMS and VN datasets enable more comprehensive interpretation of both ground and satellite-based estimation uncertainties. To support physical validation efforts eight (one) field campaigns have been conducted in the pre (post) launch era. The campaigns span regimes from northern latitude cold-season snow to warm tropical rain. Most recently the Integrated Precipitation and Hydrology Experiment (IPHEx) took place in the mountains of North Carolina and involved combined airborne and ground-based measurements of orographic precipitation and hydrologic processes underneath the GPM Core satellite. One more U.S. GV field campaign (OLYMPEX) is planned for late 2015 and will address cold-season precipitation estimation, process and hydrology in the orographic and oceanic domains of western Washington State. Finally, continuous direct and physical validation

  5. Rework of the ERA software system: ERA-8

    NASA Astrophysics Data System (ADS)

    Pavlov, D.; Skripnichenko, V.

    2015-08-01

    The software system that has been powering many products of the IAA during decades has undergone a major rework. ERA has capabilities for: processing tables of observations of different kinds, fitting parameters to observations, integrating equations of motion of the Solar system bodies. ERA comprises a domain-specific language called SLON, tailored for astronomical tasks. SLON provides a convenient syntax for reductions of observations, choosing of IAU standards to use, applying rules for filtering observations or selecting parameters for fitting. Also, ERA includes a table editor and a graph plotter. ERA-8 has a number of improvements over previous versions such as: integration of the Solar system and TT xA1 TDB with arbitrary number of asteroids; option to use different ephemeris (including DE and INPOP); integrator with 80-bit floating point. The code of ERA-8 has been completely rewritten from Pascal to C (for numerical computations) and Racket (for running SLON programs and managing data). ERA-8 is portable across major operating systems. The format of tables in ERA-8 is based on SQLite. The SPICE format has been chosen as the main format for ephemeris in ERA-8.

  6. Modulation and Coding for NASA's New Space Communications Architecture

    NASA Technical Reports Server (NTRS)

    Deutsch, Leslie J.; Stocklin, Frank J.; Rush, John J.

    2008-01-01

    With the release in 2006 of NASA's Space Communications and Navigation Architecture, the agency defined its vision for the future in these areas. The results reported in this paper help define the myriad communications links included in this architecture through the year 2030. While these results represent the work of multiple NASA Centers and some of the best experts in the Agency, this is only a first step toward developing international telecommunication link standards that will take the world into the next era of space exploration.

  7. Implementing DSpace at NASA Langley Research Center

    NASA Technical Reports Server (NTRS)

    Lowe, Greta

    2007-01-01

    This presentation looks at the implementation of the DSpace institutional repository system at the NASA Langley Technical Library. NASA Langley Technical Library implemented DSpace software as a replacement for the Langley Technical Report Server (LTRS). DSpace was also used to develop the Langley Technical Library Digital Repository (LTLDR). LTLDR contains archival copies of core technical reports in the aeronautics area dating back to the NACA era and other specialized collections relevant to the NASA Langley community. Extensive metadata crosswalks were created to facilitate moving data from various systems and formats to DSpace. The Dublin Core metadata screens were also customized. The OpenURL standard and Ex Libris Metalib are being used in this environment to assist our customers with either discovering full-text content or with initiating a request for the item.

  8. Workshop on NASA workstation technology

    NASA Technical Reports Server (NTRS)

    Brown, Robert L.

    1990-01-01

    RIACS hosted a workshop which was designed to foster communication among those people within NASA working on workstation related technology, to share technology, and to learn about new developments and futures in the larger university and industrial workstation communities. Herein, the workshop is documented along with its conclusions. It was learned that there is both a large amount of commonality of requirements and a wide variation in the modernness of in-use technology among the represented NASA centers.

  9. NASA's Discovery Program

    NASA Astrophysics Data System (ADS)

    Kicza, Mary; Bruegge, Richard Vorder

    1995-01-01

    NASA's Discovery Program represents an new era in planetary exploration. Discovery's primary goal: to maintain U.S. scientific leadership in planetary research by conducting a series of highly focused, cost effective missions to answer critical questions in solar system science. The Program will stimulate the development of innovative management approaches by encouraging new teaming arrangements among industry, universities and the government. The program encourages the prudent use of new technologies to enable/enhance science return and to reduce life cycle cost, and it supports the transfer of these technologies to the private sector for secondary applications. The Near-Earth Asteroid Rendezvous and Mars Pathfinder missions have been selected as the first two Discovery missions. Both will be launched in 1996. Subsequent, competitively selected missions will be conceived and proposed to NASA by teams of scientists and engineers from industry, academia, and government organizations. This paper summarizes the status of Discovery Program planning.

  10. NASA Environmentally Responsible Aviation's Highly-Loaded Front Block Compressor Demonstration

    NASA Technical Reports Server (NTRS)

    Celestina, Mark

    2017-01-01

    The ERA project was created in 2009 as part of NASAs Aeronautics Research Mission Directorates (ARMD) Integrated Systems Aviation Program (IASP). The purpose of the ERA project was to explore and document the feasibility, benefit, and technical risk of vehicles concepts and enabling technologies to reduce aviations impact on the environment. The metrics for this technology is given in Figure 1 with the N+2 metrics highlighted in green. It is anticipated that the United States air transportation system will continue to expand significantly over the next few decades thus adversely impacting the environment unless new technology is incorporated to simultaneously reduce nitrous oxides (NOx), noise and fuel consumption. In order to achieve the overall goals and meet the technology insertion challenges, these goals were divided into technical challenges that were to be achieved during the execution of the ERA project. Technical challenges were accomplished through test campaigns conducted by Integrated Technology Demonstration (ITDs). ERAs technical performance period ended in 2015.

  11. Ten Sins Challenging Education in the Contemporary Global Era: A Philosophical Essay

    ERIC Educational Resources Information Center

    Sinagatullin, Ilghiz M.

    2004-01-01

    According to this author, the modern epoch is characterized by a decrease of vital spirituality and an increase of materialistic values and virtues. This article discusses what the author views as the ten sins challenging education in the contemporary global era. These are: (1) the shrinking of spiritual values; (2) corruption; (3) sexual…

  12. Piloted Evaluation of Modernized Limited Authority Control Laws in the NASA-Ames Vertical Motion Simulator (VMS)

    NASA Technical Reports Server (NTRS)

    Sahasrabudhe, Vineet; Melkers, Edgar; Faynberg, Alexander; Blanken, Chris L.

    2003-01-01

    The UH-60 BLACK HAWK was designed in the 1970s, when the US Army primarily operated during the day in good visual conditions. Subsequently, the introduction of night-vision goggles increased the BLACK HAWK'S mission effectiveness, but the accident rate also increased. The increased accident rate is strongly tied to increased pilot workload as a result of a degradation in visual cues. Over twenty years of research in helicopter flight control and handling qualities has shown that these degraded handling qualities can be recovered by modifying the response type of the helicopter in low speed flight. Sikorsky Aircraft Corporation initiated a project under the National Rotorcraft Technology Center (NRTC) to develop modern flight control laws while utilizing the existing partial authority Stability Augmentation System (SAS) of the BLACK HAWK. This effort resulted in a set of Modernized Control Laws (MCLAWS) that incorporate rate command and attitude command response types. Sikorsky and the US Army Aeroflightdynamics Directorate (AFDD) conducted a piloted simulation on the NASA-Ames Vertical h4otion Simulator, to assess potential handling qualities and to reduce the risk of subsequent implementation and flight test of these modern control laws on AFDD's EH-60L helicopter. The simulation showed that Attitude Command Attitude Hold control laws in pitch and roll improve handling qualities in the low speed flight regime. These improvements are consistent across a range of mission task elements and for both good and degraded visual environments. The MCLAWS perform better than the baseline UH-60A control laws in the presence of wind and turbulence. Finally, while the improved handling qualities in the pitch and roll axis allow the pilot to pay more attention to the vertical axis and hence altitude performance also improves, it is clear from pilot comments and altitude excursions that the addition of an Altitude Hold function would further reduce workload and improve overall

  13. NASA Satellite Gives a Clear View for NASA's LADEE Launch

    NASA Image and Video Library

    2013-09-06

    era of space communications by becoming NASA's first high rate, two-way, space laser system. Live coverage of the launch can be seen beginning at 9:30 p.m. EDT on NASA-TV at: www.nasa.gov/ntv For more information about LADEE, visit: www.nasa.gov/ladee NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

  14. LTPP Climate Tool [Tech Brief

    DOT National Transportation Integrated Search

    2017-01-01

    This Product Brief describes the Long-Term Pavement Performance (LTPP) Climate Tool (intended for use by infrastructure engineers) that provides convenient access to the National Aeronautics and Space Administration (NASA) Modern-Era Retrospective An...

  15. NASA's approach to commercial cargo and crew transportation

    NASA Astrophysics Data System (ADS)

    Stone, Dennis; Lindenmoyer, Alan; French, George; Musk, Elon; Gump, David; Kathuria, Chirinjeev; Miller, Charles; Sirangelo, Mark; Pickens, Tom

    2008-07-01

    To stimulate the commercial space industry and potentially serve the logistics needs of the International Space Station (ISS) in the post-Space Shuttle era, the National Aeronautics and Space Administration (NASA) in 2006 began the Commercial Orbital Transportation Services (COTS) initiative. NASA entered into agreements with two U.S. firms, Rocketplane Kistler and Space Exploration Technologies to share up to 485,000,000 USD to demonstrate cargo transportation services to and from Low Earth orbit (LEO), with an option for additional funds to demonstrate human transportation services. Subsequently, NASA also entered into unfunded agreements with five companies to develop innovative space transportation capabilities. This paper reviews this unique initiative, describes the concepts of these seven companies, and discusses the potential of this emerging industry to make LEO more accessible.

  16. Mortality among people living with HIV/AIDS with non-small-cell lung cancer in the modern HAART Era.

    PubMed

    Smith, Danielle M; Salters, Kate A; Eyawo, Oghenowede; Franco-Villalobos, Conrado; Jabbari, Shahab; Wiseman, Sam M; Press, Natasha; Montaner, Julio S G; Man, S F Paul; Hull, Mark; Hogg, Robert S

    2018-02-07

    People living with HIV (PLWHA) with adequate access to modern combination antiretroviral therapy (cART) are living longer and experiencing reduced AIDS-related morbidity and mortality. However, increases in non-AIDS related conditions, such as certain cancers, have accompanied these therapeutic advances over time. As such, our study objective was to determine the impact of HIV on all-cause and lung cancer-specific mortality amongst PLWHA with diagnoses of non-small-cell lung cancer (NSCLC) and HIV-negative individuals with NSCLC. This analysis was inclusive of PLWHA on and off cART over the age of 19 years and a 10% comparison sample from the BC population ≥19 years, over a 13-year period (2000-2013). Kaplan-Meier estimates, Cox PH models, and competing risk analysis for all-cause and cause-specific mortality (respectively) compared PLWHA to HIV-negative individuals, controlling for age, gender, cancer stage, co-morbidities; and nadir CD4 count, viral load, and injection drug use for a HIV-positive specific analysis. We identified 71 PLWHA and 2463 HIV-negative individuals diagnosed with NSCLC between 2000 and 2013. PLWHA with NSCLC were diagnosed at a significantly younger age than HIV-negative individuals (median age 57 vs 71 years, p < 0.01). We found no significant difference in lung cancer-specific mortality. However, in multivariate analysis, HIV was associated with greater all-cause mortality (adjusted hazard ratio [aHR]:1.44; 95% confidence interval [CI]: 1.08-1.90), with median survival of 4 months for PLWHA, and 10 months for HIV-negative. Higher nadir CD4 count was protective against mortality (aHR: 0.33, 95% CI: 0.17-0.64) amongst PLWHA in multivariate analysis. Our analysis suggests that PLWHA in the modern cART era experience similar lung cancer survival outcomes compared to the general BC population with NSCLC. However, we also observed significantly higher all-cause mortality among PLWHA with NSCLC, which may warrant further inquiry into the

  17. NASA Environmentally Responsible Aviation Hybrid Wing Body Flow-Through Nacelle Wind Tunnel CFD

    NASA Technical Reports Server (NTRS)

    Schuh, Michael J.; Garcia, Jospeh A.; Carter, Melissa B.; Deere, Karen A.; Stremel, Paul M.; Tompkins, Daniel M.

    2016-01-01

    Wind tunnel tests of a 5.75% scale model of the Boeing Hybrid Wing Body (HWB) configuration were conducted in the NASA Langley Research Center (LaRC) 14'x22' and NASA Ames Research Center (ARC) 40'x80' low speed wind tunnels as part of the NASA Environmentally Responsible Aviation (ERA) Project. Computational fluid dynamics (CFD) simulations of the flow-through nacelle (FTN) configuration of this model were performed before and after the testing. This paper presents a summary of the experimental and CFD results for the model in the cruise and landing configurations.

  18. NASA Environmentally Responsible Aviation Hybrid Wing Body Flow-Through Nacelle Wind Tunnel CFD

    NASA Technical Reports Server (NTRS)

    Schuh, Michael J.; Garcia, Joseph A.; Carter, Melissa B.; Deere, Karen A.; Tompkins, Daniel M.; Stremel, Paul M.

    2016-01-01

    Wind tunnel tests of a 5.75 scale model of the Boeing Hybrid Wing Body (HWB) configuration were conducted in the NASA Langley Research Center (LaRC) 14x22 and NASA Ames Research Center (ARC) 40x80 low speed wind tunnels as part of the NASA Environmentally Responsible Aviation (ERA) Project. Computational fluid dynamics (CFD) simulations of the flow-through nacelle (FTN) configuration of this model were performed before and after the testing. This paper presents a summary of the experimental and CFD results for the model in the cruise and landing configurations.

  19. Astronaut medical selection during the shuttle era: 1981-2011.

    PubMed

    Johnston, Smith L; Blue, Rebecca S; Jennings, Richard T; Tarver, William J; Gray, Gary W

    2014-08-01

    U.S. astronauts undergo extensive job-related screening and medical examinations prior to selection in order to identify candidates optimally suited for careers in spaceflight. Screening medical standards evolved over many years and after extensive spaceflight experience. These standards assess health-related risks for each astronaut candidate, minimizing the potential for medical impact on future mission success. This document discusses the evolution of the Shuttle-era medical selection standards and the most common reasons for medical dis-qualification of applicants. Data for astronaut candidate finalists were compiled from medical records and NASA archives from the period of 1978 to 2004 and were retrospectively reviewed for medically disqualifying conditions. During Shuttle selection cycles, a total of 372 applicants were disqualified due to 425 medical concerns. The most common disqualifying conditions included visual, cardiovascular, psychiatric, and behavioral disorders. During this time period, three major expert panel reviews resulted in refinements and alterations to selection standards for future cycles. Shuttle-era screening, testing, and specialist evaluations evolved through periodic expert reviews, evidence-based medicine, and astronaut medical care experience. The Shuttle medical program contributed to the development and implementation of NASA and international standards, longitudinal data collection, improved medical care, and occupational surveillance models. The lessons learned from the Shuttle program serve as the basis for medical selection for the ISS, exploration-class missions, and for those expected to participate in commercial spaceflight.

  20. NASA evolution of exploration architectures

    NASA Technical Reports Server (NTRS)

    Roberts, Barney B.

    1991-01-01

    A series of charts and diagrams is used to provide a detailed overview of the evolution of NASA space exploration architectures. The pre-Apollo programs including the Werner von Braun feasibility study are discussed and the evolution of the Apollo program itself is treated in detail. The post-Apollo era is reviewed and attention is given to the resurgence of strategic planning exemplified by both ad hoc and formal efforts at planning. Results of NASA's study of the main elements of the Space Exploration Initiative which examined technical scenarios, science opportunities, required technologies, international considerations, institutional strengths and needs, and resource estimates are presented. The 90-day study concludes that, among other things, major investments in challenging technologies are required, the scientific opportunities provided by the program are considerable, current launch capabilities are inadequate, and Space Station Freedom is essential.

  1. Post-Genome Era Pedagogy: How a BS Biotechnology Program Benefits the Liberal Arts Institution

    ERIC Educational Resources Information Center

    Eden, Peter

    2005-01-01

    Genomics profoundly affects society, because genome sequence information is widely used in such areas as genetic testing, genomic medicine/vaccine development, and so forth. Therefore, a responsibility to modernize science curricula exists for "post-genome era" educators. At my university, we developed a BS biotechnology program within a…

  2. NASA Acting Administrator Robert Lightfoot presents the 2018 "St

    NASA Image and Video Library

    2018-02-12

    NASA Acting Administrator Robert Lightfoot delivers the "State of NASA", February 12, 2018, at the Marshall Space Flight Center in Huntsville, Alabama. In his address, Lightfoot discussed what the President's Fiscal Year 2019 budget request means for America's space agency. According to Lightfoot, it "reflects the administration's confidence that America will lead the way back to the Moon and take the next giant leap". Lightfoot delivered the "State of NASA" address in Marshall's Center for Advanced Manufacturing where engineers are pushing boundaries in the fields of additive manufacturing, 3D printing, and more. Hardware for NASA's Space Launch System and a model of the agency's Orion spacecraft served as a backdrop for the annual event. SLS, which is managed by Marshall, will enable a new era of exploration beyond Earth's orbit by launching astronauts on missions to deep-space destinations including the Moon and Mars.

  3. Mesmer minus magic: hypnosis and modern medicine.

    PubMed

    Spiegel, David

    2002-10-01

    The implications and effects of the French commission that passed judgment on Mesmer's work is examined in light of the pioneering role of hypnosis as the first Western conception of a psychotherapy, the ancient philosophical debate between idealism and empiricism, and the conflict in modern medicine between biotechnological emphasis on cure and the need for care as many previously terminal illnesses are converted to chronic diseases. The panel's report is interpreted as negative about the literal theory of animal magnetism but actually supportive of the potential therapeutic power of suggestion and "positive thinking." This aspect of hypnosis is described as a forerunner of modern cognitive therapies of depression and other illnesses. The panel exerted a constructive effect in applying scientific method and rigorous evaluation to hypnotic treatment, an application of Enlightenment philosophy that presaged the Flexner era in modern medicine. Both hypnosis and medicine ultimately benefited.

  4. The Role and Training of NASA Astronauts in the Post-Shuttle Era

    NASA Technical Reports Server (NTRS)

    2011-01-01

    In May 2010 the National Research Council (NRC) was asked by NASA to address several questions related to the Astronaut Corps. The NRC's Committee on Human Spaceflight Crew Operations was tasked to: 1. How should the role and size of the activities managed by the Johnson Space Center Flight Crew Operations Directorate change following space shuttle retirement and completion of the assembly of the International Space Station (ISS)? 2. What are the requirements for crew-related ground-based facilities after the Space Shuttle program ends? 3. Is the fleet of aircraft used for training the Astronaut Corps a cost-effective means of preparing astronauts to meet the requirements of NASA's human spaceflight program? Are there more cost-effective means of meeting these training requirements? Although the future of NASA's human spaceflight program has garnered considerable discussion in recent years, and there is considerable uncertainty about what that program will involve in the coming years, the committee was not tasked to address whether or not human spaceflight should continue, or what form it should take. The committee's task restricted it to studying those activities managed by the Flight Crew Operations Directorate, or those closely related to its activities, such as crew-related ground-based facilities and the training aircraft.

  5. [Overall digitalization: leading innovation of endodontics in big data era].

    PubMed

    Ling, J Q

    2016-04-09

    In big data era, digital technologies bring great challenges and opportunities to modern stomatology. The applications of digital technologies, such as cone-beam CT(CBCT), computer aided design,(CAD)and computer aided manufacture(CAM), 3D printing and digital approaches for education , provide new concepts and patterns to the treatment and study of endodontic diseases. This review provides an overview of the application and prospect of commonly used digital technologies in the development of endodontics.

  6. White House Forum on Modernizing Government

    NASA Image and Video Library

    2010-01-14

    U.S. President Barack Obama speaks at the opening session of the Forum on Modernizing Government, Thursday, Jan. 14, 2010, in the Eisenhower Executive Office Building in Washington. As part of his commitment to change how business is done in Washington and instill a new sense of responsibility for taxpayer dollars, the President welcomed more than 50 of the country’s top CEOs, deputy secretaries, including NASA's Deputy Administrator Lori Garver and department chief information officers to the forum. Photo Credit: (NASA/Bill Ingalls)

  7. The Italian Middle School in a Deregulation Era: Modernity through Path-Dependency and Global Models

    ERIC Educational Resources Information Center

    Mincu, Monica E.

    2015-01-01

    In the current context of intensified moves towards educational deregulation, the configuration of the Italian middle school and its relationship to education governance is an interesting case. Historically, it represents a unique example of the successful "decision-making" model of the welfarist era. Despite some internal constraints,…

  8. NASA Acting Administrator Robert Lightfoot presents the 2018 "St

    NASA Image and Video Library

    2018-02-12

    Marshall Space Flight Center Director Todd May introduces NASA Acting Adminstrator Robert Lightfoot prior to his delivery of the "State of NASA", February 12, 2018, at the Marshall Space Flight Center in Huntsville, Alabama. In his address, Lightfoot discussed what the President's Fiscal Year 2019 budget request means for America's space agency. According to Lightfoot, it "reflects the administration's confidence that America will lead the way back to the Moon and take the next giant leap". Lightfoot delivered the "State of NASA" address in Marshall's Center for Advanced Manufacturing where engineers are pushing boundaries in the fields of additive manufacturing, 3D printing, and more. Hardware for NASA's Space Launch System and a model of the agency's Orion spacecraft served as a backdrop for the annual event. SLS, which is managed by Marshall, will enable a new era of exploration beyond Earth's orbit by launching astronauts on missions to deep-space destinations including the Moon and Mars.

  9. Planning For Multiple NASA Missions With Use Of Enabling Radioisotope Power

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    S.G. Johnson; K.L. Lively; C.C. Dwight

    Since the early 1960’s the Department of Energy (DOE) and its predecessor agencies have provided radioisotope power systems (RPS) to NASA as an enabling technology for deep space and various planetary missions. They provide reliable power in situations where solar and/or battery power sources are either untenable or would place an undue mass burden on the mission. In the modern era of the past twenty years there has been no time that multiple missions have been considered for launching from Kennedy Space Center (KSC) during the same year. The closest proximity of missions that involved radioisotope power systems would bemore » that of Galileo (October 1989) and Ulysses (October 1990). The closest that involved radioisotope heater units would be the small rovers Spirit and Opportunity (May and July 2003) used in the Mars Exploration Rovers (MER) mission. It can be argued that the rovers sent to Mars in 2003 were essentially a special case since they staged in the same facility and used a pair of small launch vehicles (Delta II). This paper examines constraints on the frequency of use of radioisotope power systems with regard to launching them from Kennedy Space Center using currently available launch vehicles. This knowledge may be useful as NASA plans for its future deep space or planetary missions where radioisotope power systems are used as an enabling technology. Previous descriptions have focused on single mission chronologies and not analyzed the timelines with an emphasis on multiple missions.« less

  10. All that glitters: fool's gold in the early-modern era.

    PubMed

    Roos, Anna Marie

    2008-12-01

    Natural philosophers of the early-modern period perceived fool's gold or iron pyrites as a substance required for the formation of metals, and chemists such as Johann Glauber speculated the vitriol produced from pyrites was the source of the legendary philosopher's stone. The sulphurous exhalations of fool's gold were also thought by members of the early Royal Society to be the basis of a variety of meteorological, geological and medical effects, including the production of thunder, lightning, earthquakes and volcanoes, fossilisation and petrifaction, as well as the principal cause of bladder and gallstones.

  11. NASA's Ares I and Ares V Launch Vehicles -- Effective Space Operations Through Efficient Ground Operations

    NASA Technical Reports Server (NTRS)

    Dumbacher, Daniel L.; Singer, Christopher E.; Onken, Jay F.

    2008-01-01

    elements before shipping to the Kennedy Space Center for launch operations. This paper provides top-level details for several cost saving initiatives, including both process and product improvements that will result in space transportation systems that are designed with operations efficiencies in mind. The Engineering Directorate provides both the intellectual capital embodied in an experienced workforce and unique facilities in which to validate the information technology tools that allow a nationwide team to collaboratively connect across miles that separate them and the engineering disciplines that integrate various piece parts into a whole system. As NASA transforms ground-based operations, it also is transitioning its workforce from an era of intense hands-on labor to a new one of mechanized conveniences and robust hardware with simpler interfaces. Ensuring that space exploration is on sound footing requires that operations efficiencies be designed into the transportation system and implemented in the development stage. Applying experience gained through decades of ground and space op'erations, while using value-added processes and modern business and engineering tools, is the philosophy upon which a new era of exploration will be built to solve some of the most pressing exploration challenges today -- namely, safety, reliability, and affordability.

  12. NASA commercial programs

    NASA Technical Reports Server (NTRS)

    1990-01-01

    Highlights of NASA-sponsored and assisted commercial space activities of 1989 are presented. Industrial R and D in space, centers for the commercial development of space, and new cooperative agreements are addressed in the U.S. private sector in space section. In the building U.S. competitiveness through technology section, the following topics are presented: (1) technology utilization as a national priority; (2) an exploration of benefits; and (3) honoring Apollo-Era spinoffs. International and domestic R and D trends, and the space sector are discussed in the section on selected economic indicators. Other subjects included in this report are: (1) small business innovation; (2) budget highlights and trends; (3) commercial programs management; and (4) the commercial programs advisory committee.

  13. Lunar Colonization and NASA's Exploration Changes

    NASA Astrophysics Data System (ADS)

    Gavert, Raymond B.

    2006-01-01

    Space colonization is not part of NASA's mission planning. NASA's exploration vision, mission goals and program implementations, however, can have an important affect on private lunar programs leading towards colonization. NASA's exploration program has been described as a journey not a race. It is not like the Apollo mission having tight schedules and relatively unchanging direction. NASA of this era has competing demands from the areas of aeronautics, space science, earth science, space operations and, there are competing demands within the exploration program itself. Under the journey not a race conditions, an entrepreneur thinking about building a hotel on the Moon, with a road to an exploration site, might have difficulty determining where and when NASA might be at a particular place on the Moon. Lunar colonization advocates cannot depend on NASA or other nations with space programs to lead the way to colonization. They must set their own visions, mission goals and schedules. In implementing their colonization programs they will be resource limited. They would be like ``hitchhikers'' following the programs of spacefaring nations identifying programs that might have a fit with their vision and be ready to switch to other programs that may take them in the colonization direction. At times they will have to muster their own limited resources and do things themselves where necessary. The purpose of this paper is to examine current changes within NASA, as a lunar colonization advocate might do, in order to see where there might be areas for fitting into a lunar colonization strategy. The approach will help understand how the ``hitchhiking'' technique might be better utilized.

  14. International Cooperation at NASA

    NASA Astrophysics Data System (ADS)

    Tawney, Timothy; Feldstein, Karen

    International cooperation is a cornerstone principle of NASA’s activities, especially within the activities of the Science Mission Directorate. Nearly two thirds of the flight missions in which NASA leads or participates involve international cooperation. Numerous ground based activities also rely on international cooperation, whether because of unique expertise, unique geography, or the need for a global response. Going forward, in an era of tighter budgets and a more integrated global perspective, NASA and the rest of the space agencies around the world will be forced to work more closely together, in a broader array of activities than ever before, in order to be able to afford to push the boundaries of space exploration. The goal of this presentation is to provide an overview of NASA’s current international science cooperative activities. It will include a discussion of why NASA conducts international cooperation and look at the mechanisms through which international cooperation can occur at NASA, including peer-to-peer development of relationships. It will also discuss some of the limiting factors of international cooperation, such as export control, and ways in which to manage those constraints. Finally, the presentation would look at some of the present examples where NASA is working to increase international cooperation and improve coordination. Case studies will be used to demonstrate these mechanisms and concepts. For example, NASA continues to participate in international coordination groups such as the International Mars Exploration Working Group (IMEWG) and International Space Exploration Coordination Group (ISECG), but is expanding into new areas as well. NASA is one of the leaders in expanding and improving international coordination in the area of Near-Earth Object detection, characterization, and mitigation. Having participated in the first meetings of such groups as the International Asteroid Warning Network (IAWN) and Space Missions Planning

  15. NASA Historical Data Book. Volume 6; NASA Space Applications, Aeronautics and Space Research and Technology, Tracking and Data Acquisition/Support Operations, Commercial Programs and

    NASA Technical Reports Server (NTRS)

    Rumerman, Judy A.

    2000-01-01

    This sixth volume of the NASA Historical Data Book is a continuation of those earlier efforts. This fundamental reference tool presents information, much of it statistical, documenting the development of several critical areas of NASA responsibility for the period between 1979 and 1988. This volume includes detailed information on the space applications effort, the development and operation of aeronautics and space research and technology programs, tracking and data acquisition/space operations, commercial programs, facilities and installations, personnel, and finances and procurement during this era. Special thanks are owed to the student research assistants who gathered and input much of the tabular material-a particularly tedious undertaking. There are numerous people at NASA associated with historical study, technical information, and the mechanics of publishing who helped in myriad ways in the preparation of this historical data book.

  16. NASA University Program Management Information System

    NASA Technical Reports Server (NTRS)

    2000-01-01

    As basic policy, NASA believes that colleges and universities should be encouraged to participate in the nation's space and aeronautics program to the maximum extent practicable. Indeed, universities are considered as partners with government and industry in the nation's aerospace program. NASA:s objective is to have them bring their scientific, engineering, and social research competence to bear on aerospace problems and on the broader social, economic, and international implications of NASA's technical and scientific programs. It is expected that, in so doing, universities will strengthen both their research and their educational capabilities to contribute more effectively to the national well-being. NASA field codes and certain Headquarters program offices provide funds for those activities in universities which contribute to the mission needs of that particular NASA element. Although NASA has no predetermined amount of money to devote to university activities, the effort funded each year is substantial. This annual report is one means of documenting the NASA-university relationship, frequently denoted, collectively, as NASA's University Program. This report is consistent with agency accounting records, as the data is obtained from NASA:s Financial and Contractual Status (FACS) System, operated by the Financial Management Division and the Procurement Office. However, in accordance with interagency agreements, the orientation differs from that required for financial or procurement purposes. Any apparent discrepancies between this report and other NASA procurement or financial reports stem from the selection criteria for the data.* This report was prepared by the Education Division/FE, Office of Human Resources and Education, using a management information system which was modernized during FY 1993.

  17. Computational Nanoelectronics and Nanotechnology at NASA ARC

    NASA Technical Reports Server (NTRS)

    Saini, Subhash; Kutler, Paul (Technical Monitor)

    1998-01-01

    Both physical and economic considerations indicate that the scaling era of CMOS will run out of steam around the year 2010. However, physical laws also indicate that it is possible to compute at a rate of a billion times present speeds with the expenditure of only one Watt of electrical power. NASA has long-term needs where ultra-small semiconductor devices are needed for critical applications: high performance, low power, compact computers for intelligent autonomous vehicles and Petaflop computing technology are some key examples. To advance the design, development, and production of future generation micro- and nano-devices, IT Modeling and Simulation Group has been started at NASA Ames with a goal to develop an integrated simulation environment that addresses problems related to nanoelectronics and molecular nanotechnology. Overview of nanoelectronics and nanotechnology research activities being carried out at Ames Research Center will be presented. We will also present the vision and the research objectives of the IT Modeling and Simulation Group including the applications of nanoelectronic based devices relevant to NASA missions.

  18. Computational Nanoelectronics and Nanotechnology at NASA ARC

    NASA Technical Reports Server (NTRS)

    Saini, Subhash

    1998-01-01

    Both physical and economic considerations indicate that the scaling era of CMOS will run out of steam around the year 2010. However, physical laws also indicate that it is possible to compute at a rate of a billion times present speeds with the expenditure of only one Watt of electrical power. NASA has long-term needs where ultra-small semiconductor devices are needed for critical applications: high performance, low power, compact computers for intelligent autonomous vehicles and Petaflop computing technolpgy are some key examples. To advance the design, development, and production of future generation micro- and nano-devices, IT Modeling and Simulation Group has been started at NASA Ames with a goal to develop an integrated simulation environment that addresses problems related to nanoelectronics and molecular nanotecnology. Overview of nanoelectronics and nanotechnology research activities being carried out at Ames Research Center will be presented. We will also present the vision and the research objectives of the IT Modeling and Simulation Group including the applications of nanoelectronic based devices relevant to NASA missions.

  19. Application of Modern Fortran to Spacecraft Trajectory Design and Optimization

    NASA Technical Reports Server (NTRS)

    Williams, Jacob; Falck, Robert D.; Beekman, Izaak B.

    2018-01-01

    In this paper, applications of the modern Fortran programming language to the field of spacecraft trajectory optimization and design are examined. Modern object-oriented Fortran has many advantages for scientific programming, although many legacy Fortran aerospace codes have not been upgraded to use the newer standards (or have been rewritten in other languages perceived to be more modern). NASA's Copernicus spacecraft trajectory optimization program, originally a combination of Fortran 77 and Fortran 95, has attempted to keep up with modern standards and makes significant use of the new language features. Various algorithms and methods are presented from trajectory tools such as Copernicus, as well as modern Fortran open source libraries and other projects.

  20. NASA Environmentally Responsible Aviation Projects Propulsion Technology Phase I Overview and Highlights of Accomplishments

    NASA Technical Reports Server (NTRS)

    Suder, Kenneth L.; Delaat, John C.

    2012-01-01

    The NASA Environmentally Responsible Aviation (ERA) Project is focused on developing and demonstrating integrated systems technologies to TRL 4-6 by 2020 that enable reduced fuel burn, emissions, and noise for futuristic air vehicles. The specific goals aim to simultaneously reduce fuel burn by 50%, reduce Landing and Take-off Nitrous Oxides emissions by 75% relative to the CAEP 6 guidelines, and reduce cumulative noise by 42 Decibels relative to the Stage 4 guidelines. These goals apply to the integrated vehicle and propulsion system and are based on a reference mission of 3000nm flight of a Boeing 777-200 with GE90 engines. This paper will focus primarily on the ERA propulsion technology portfolio, which consists of advanced combustion, propulsor, and core technologies to enable these integrated air vehicle systems goals. An overview of the ERA propulsion technologies will be described and highlights of the results obtained during the first phase of ERA will be presented.

  1. Engineering a Business School in a Former Soviet-Era Closed City: The Case of Omsk, Siberia

    ERIC Educational Resources Information Center

    Chukhlomin, Valeri; Chukhlomina, Irina

    2013-01-01

    This article describes a modernization project undertaken by a nationally accredited Russian university located in Omsk, Siberia, and aimed at developing a new international business school. A unique feature of the project is that it was successfully implemented in a former Soviet-era closed city. Until 1991, the university hadn't had any…

  2. Overview of the NASA Environmentally Responsible Aviation Project's Propulsion Technology Portfolio

    NASA Technical Reports Server (NTRS)

    Suder, Kenneth L.

    2012-01-01

    The NASA Environmentally Responsible Aviation (ERA) Project is focused on developing and demonstrating integrated systems technologies to TRL 4-6 by 2020 that enable reduced fuel burn, emissions, and noise for futuristic air vehicles. The specific goals aim to simultaneously reduce fuel burn by 50%, reduce Landing and Take-off Nitrous Oxides emissions by 75% relative to the CAEP 6 guidelines, and reduce cumulative noise by 42 Decibels relative to the Stage 4 guidelines. These goals apply to the integrated vehicle and propulsion system and are based on a reference mission of 3000nm flight of a Boeing 777-200 with GE90 engines. This paper will focus primarily on the ERA propulsion technology portfolio, which consists of advanced combustion, propulsor, and core technologies to enable these integrated air vehicle systems goals. An overview of the ERA propulsion technologies will be described and the status and results to date will be presented.

  3. Radiation-Induced Cardiac Toxicity After Therapy for Breast Cancer: Interaction Between Treatment Era and Follow-Up Duration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Demirci, Senem; Department of Radiation Oncology, Duke University Medical Center, Durham, NC; Nam, Jiho

    2009-03-15

    Purpose: Cardiac toxicity after breast radiotherapy (RT) has been widely described in 'older' RT trials (i.e., using larger fraction sizes, wide RT fields, and orthovoltage energy). The results from more 'modern' RT trials have shown less cardiac toxicity. The comparisons between the 'older' and 'modern' trials are confounded by the longer follow-up time in the 'older' trials. We systematically assessed the effect of treatment era and follow-up duration on the reported rates of cardiac toxicity associated with RT. Methods and Materials: The published data were surveyed using PubMed to identify studies using 'breast cancer,' 'irradiation/radiotherapy,' 'cardiac/heart,' and 'toxicity/morbidity/mortality' in amore » keyword search. Relevant data were extracted from the identified trials. The trials were defined as 'older' (patient accrual start year before 1980) and 'modern' (patient accrual start year in or after 1980) to segregate the trials and assess the treatment era effect. A 10-year follow-up duration was used as a cutoff to segregate and analyze trials with varying lengths of follow-up. Results: We analyzed 19 published reports of patients treated between 1968 and 2002 (5 randomized controlled trials, 5 single- or multi-institutional studies, and 9 national cancer registry database reviews). In the reviewed trials, all the older trials reported excess cardiac toxicity, typically with a median of >10-15 years of follow-up. However, the vast majority of modern RT trials had shorter median follow-up durations, typically {<=}10 years and did not report an excess toxicity risk. The modern studies lacked longer follow-up. Conclusion: Additional follow-up is needed to ensure that modern methods effectively reduce cardiac toxicity. Continued diligence to minimize cardiac exposure remains prudent.« less

  4. NASA Life Sciences Data Repositories: Tools for Retrospective Analysis and Future Planning

    NASA Technical Reports Server (NTRS)

    Thomas, D.; Wear, M.; VanBaalen, M.; Lee, L.; Fitts, M.

    2011-01-01

    As NASA transitions from the Space Shuttle era into the next phase of space exploration, the need to ensure the capture, analysis, and application of its research and medical data is of greater urgency than at any other previous time. In this era of limited resources and challenging schedules, the Human Research Program (HRP) based at NASA s Johnson Space Center (JSC) recognizes the need to extract the greatest possible amount of information from the data already captured, as well as focus current and future research funding on addressing the HRP goal to provide human health and performance countermeasures, knowledge, technologies, and tools to enable safe, reliable, and productive human space exploration. To this end, the Science Management Office and the Medical Informatics and Health Care Systems Branch within the HRP and the Space Medicine Division have been working to make both research data and clinical data more accessible to the user community. The Life Sciences Data Archive (LSDA), the research repository housing data and information regarding the physiologic effects of microgravity, and the Lifetime Surveillance of Astronaut Health (LSAH-R), the clinical repository housing astronaut data, have joined forces to achieve this goal. The task of both repositories is to acquire, preserve, and distribute data and information both within the NASA community and to the science community at large. This is accomplished via the LSDA s public website (http://lsda.jsc.nasa.gov), which allows access to experiment descriptions including hardware, datasets, key personnel, mission descriptions and a mechanism for researchers to request additional data, research and clinical, that is not accessible from the public website. This will result in making the work of NASA and its partners available to the wider sciences community, both domestic and international. The desired outcome is the use of these data for knowledge discovery, retrospective analysis, and planning of future

  5. Modernity in Two Great American Writers' Vision: Ernest Miller Hemingway and Scott Fitzgerald

    ERIC Educational Resources Information Center

    Keshmiri, Fahimeh; Darzikola, Shahla Sorkhabi

    2016-01-01

    Scott Fitzgerald and Ernest Hemingway, American memorable novelists have had philosophic ideas about modernity. In fact their idea about existential interests of American, and the effects of American system on society, is mirrored in their creative works. All through his early works, Fitzgerald echoes the existential center of his era. Obviously,…

  6. NASA University Program Management Information System

    NASA Technical Reports Server (NTRS)

    Gans, Gary

    1997-01-01

    As basic policy, NASA believes that colleges and universities should be encouraged to participate in the nation's space and aeronautics program to the maximum extent practicable. Indeed, universities are considered as partners with government and industry in the nation's aerospace program. NASA's objective is to have them bring their scientific, engineering, and social research competence to bear on aerospace problems and on the broader social, economic, and international implications of NASA's technical and scientific programs. It is expected that, in so doing, universities will strengthen both their research and their educational capabilities to contribute more effectively to the national well-being. NASA field codes and certain Headquarters program offices provide funds for those activities in universities which contribute to the mission needs of that particular NASA element. Although NASA has no predetermined amount of money to devote to university activities, the effort funded each year is substantial. This annual report is one means of documenting the NASA-university relationship, frequently denoted, collectively, as NASA's University Program. This report is consistent with agency accounting records, as the data is obtained from NASA's Financial and Contractual Status (FACS) System, operated by the Financial Management Division and the Procurement Office. However, in accordance with interagency agreements, the orientation differs from that required for financial or procurement purposes. Any apparent discrepancies between this report and other NASA procurement or financial reports stem from the selection criteria for the data. This report was prepared by the Education Division/FE, Office of Human Resources and Education, using a management information system which was modernized during FY 1993.

  7. NASA's New Discovery Missions

    NASA Image and Video Library

    2017-01-04

    On Jan. 4, 2017 NASA announced the selection of two missions to explore previously unexplored asteroids. The first mission, called Lucy, will study asteroids, known as Trojan asteroids, trapped by Jupiter’s gravity. The Psyche mission will explore a very large and rare object in the solar system’s asteroid belt that’s made of metal, and scientists believe might be the exposed core of a planet that lost its rocky outer layers from a series of violent collisions. Lucy is targeted for launch in 2021 and Psyche in 2023. Both missions have the potential to open new windows on one of the earliest eras in the history of our solar system – a time less than 10 million years after the birth of our sun.

  8. Going Boldly Beyond: Progress on NASA's Space Launch System

    NASA Technical Reports Server (NTRS)

    Singer, Jody; Crumbly, Chris

    2013-01-01

    NASA's Space Launch System is implementing an evolvable configuration approach to system development in a resource-constrained era. Legacy systems enable non-traditional development funding and contribute to sustainability and affordability. Limited simultaneous developments reduce cost and schedule risk. Phased approach to advanced booster development enables innovation and competition, incrementally demonstrating affordability and performance enhancements. Advanced boosters will provide performance for the most capable heavy lift launcher in history, enabling unprecedented space exploration benefiting all of humanity.

  9. Benefit from NASA

    NASA Image and Video Library

    2001-08-01

    Apollo-era technology spurred the development of cordless products that we take for granted everyday. In the 1960s, NASA asked Black Decker to develop a special drill that would be powerful enough to cut through hard layers of the lunar surface and be lightweight, compact, and operate under its own power source, allowing Apollo astronauts to collect lunar samples further away from the Lunar Experiment Module. In response, Black Decker developed a computer program that analyzed and optimized drill motor operations. From their analysis, engineers were able to design a motor that was powerful yet required minimal battery power to operate. Since those first days of cordless products, Black Decker has continued to refine this technology and they now sell their rechargeable products worldwide (i.e. the Dustbuster, cordless tools for home and industrial use, and medical tools.)

  10. Evaluation of ERA-interim and MERRA Cloudiness in the Southern Oceans

    NASA Technical Reports Server (NTRS)

    Naud, Catherine M.; Booth, James F.; Del Genio, Anthony D.

    2014-01-01

    The Southern Ocean cloud cover modeled by the Interim ECMWF Re-Analysis (ERA-Interim) and Modern- Era Retrospective Analysis for Research and Applications (MERRA) reanalyses are compared against Moderate Resolution Imaging Spectroradiometer (MODIS) and Multiangle Imaging Spectroradiometer (MISR) observations. ERA-Interim monthly mean cloud amounts match the observations within 5%, while MERRA significantly underestimates the cloud amount. For a compositing analysis of clouds in warm season extratropical cyclones, both reanalyses show a low bias in cloud cover. They display a larger bias to the west of the cyclones in the region of subsidence behind the cold fronts. This low bias is larger for MERRA than for ERA-Interim. Both MODIS and MISR retrievals indicate that the clouds in this sector are at a low altitude, often composed of liquid, and of a broken nature. The combined CloudSat-Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) cloud profiles confirm these passive observations, but they also reveal that low-level clouds in other parts of the cyclones are also not properly represented in the reanalyses. The two reanalyses are in fairly good agreement for the dynamic and thermodynamic characteristics of the cyclones, suggesting that the cloud, convection, or boundary layer schemes are the problem instead. An examination of the lower-tropospheric stability distribution in the cyclones from both reanalyses suggests that the parameterization of shallow cumulus clouds may contribute in a large part to the problem. However, the differences in the cloud schemes and in particular in the precipitation processes, which may also contribute, cannot be excluded.

  11. Modernization of B-2 Data, Video, and Control Systems Infrastructure

    NASA Technical Reports Server (NTRS)

    Cmar, Mark D.; Maloney, Christian T.; Butala, Vishal D.

    2012-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) Plum Brook Station (PBS) Spacecraft Propulsion Research Facility, commonly referred to as B-2, is NASA s third largest thermal-vacuum facility with propellant systems capability. B-2 has completed a modernization effort of its facility legacy data, video and control systems infrastructure to accommodate modern integrated testing and Information Technology (IT) Security requirements. Integrated systems tests have been conducted to demonstrate the new data, video and control systems functionality and capability. Discrete analog signal conditioners have been replaced by new programmable, signal processing hardware that is integrated with the data system. This integration supports automated calibration and verification of the analog subsystem. Modern measurement systems analysis (MSA) tools are being developed to help verify system health and measurement integrity. Legacy hard wired digital data systems have been replaced by distributed Fibre Channel (FC) network connected digitizers where high speed sampling rates have increased to 256,000 samples per second. Several analog video cameras have been replaced by digital image and storage systems. Hard-wired analog control systems have been replaced by Programmable Logic Controllers (PLC), fiber optic networks (FON) infrastructure and human machine interface (HMI) operator screens. New modern IT Security procedures and schemes have been employed to control data access and process control flows. Due to the nature of testing possible at B-2, flexibility and configurability of systems has been central to the architecture during modernization.

  12. Modernization of B-2 Data, Video, and Control Systems Infrastructure

    NASA Technical Reports Server (NTRS)

    Cmar, Mark D.; Maloney, Christian T.; Butala, Vishal D.

    2012-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) Plum Brook Station (PBS) Spacecraft Propulsion Research Facility, commonly referred to as B-2, is NASA's third largest thermal-vacuum facility with propellant systems capability. B-2 has completed a modernization effort of its facility legacy data, video and control systems infrastructure to accommodate modern integrated testing and Information Technology (IT) Security requirements. Integrated systems tests have been conducted to demonstrate the new data, video and control systems functionality and capability. Discrete analog signal conditioners have been replaced by new programmable, signal processing hardware that is integrated with the data system. This integration supports automated calibration and verification of the analog subsystem. Modern measurement systems analysis (MSA) tools are being developed to help verify system health and measurement integrity. Legacy hard wired digital data systems have been replaced by distributed Fibre Channel (FC) network connected digitizers where high speed sampling rates have increased to 256,000 samples per second. Several analog video cameras have been replaced by digital image and storage systems. Hard-wired analog control systems have been replaced by Programmable Logic Controllers (PLC), fiber optic networks (FON) infrastructure and human machine interface (HMI) operator screens. New modern IT Security procedures and schemes have been employed to control data access and process control flows. Due to the nature of testing possible at B-2, flexibility and configurability of systems has been central to the architecture during modernization.

  13. The Nature of Light: II. A Historical Survey from the Planck Era and Implications for Budding Physicists

    ERIC Educational Resources Information Center

    Oon, Pey Tee; Subramaniam, R.

    2009-01-01

    Following on from our previous article (Oon and Subramaniam 2009 "Phys. Educ." 44 384-91), here we trace ideas on the history of light from the Planck era to modern times. In particular, the seminal contributions of Planck, Einstein and de Broglie are highlighted. Some lesser known facets of the nature of light are also emphasized. It is stressed…

  14. Diverse transitional giant fleas from the Mesozoic era of China.

    PubMed

    Huang, Diying; Engel, Michael S; Cai, Chenyang; Wu, Hao; Nel, André

    2012-02-29

    Fleas are one of the major lineages of ectoparasitic insects and are now highly specialized for feeding on the blood of birds or mammals. This has isolated them among holometabolan insect orders, although they derive from the Antliophora (scorpionflies and true flies). Like most ectoparasitic lineages, their fossil record is meagre and confined to Cenozoic-era representatives of modern families, so that we lack evidence of the origins of fleas in the Mesozoic era. The origins of the first recognized Cretaceous stem-group flea, Tarwinia, remains highly controversial. Here we report fossils of the oldest definitive fleas--giant forms from the Middle Jurassic and Early Cretaceous periods of China. They exhibit many defining features of fleas but retain primitive traits such as non-jumping hindlegs. More importantly, all have stout and elongate sucking siphons for piercing the hides of their hosts, implying that these fleas may be rooted among the pollinating 'long siphonate' scorpionflies of the Mesozoic. Their special morphology suggests that their earliest hosts were hairy or feathered 'reptilians', and that they radiated to mammalian and bird hosts later in the Cenozoic.

  15. Studying Diurnal Variations of Aerosols with NASA MERRA-2 Reanalysis Data

    NASA Technical Reports Server (NTRS)

    Shen, Suhung; Ostrenga, Dana M.; Zeng, Jian; Vollmer, Bruce E.

    2018-01-01

    Aerosols play an important role in atmospheric dynamics, climate variations, and Earth's energy cycle by altering the radiation balance in the atmosphere through interaction with clouds, providing fertilizer for forests and canopy, and as a supply of iron to the ocean over long time periods. Studies suggest that much of the feedback between dust aerosols and dynamics is associated with diurnal and synoptic scale variability. However, the lack of sub-daily resolution of aerosols from satellite observations makes it difficult to study the diurnal characteristics, especially over tropical and subtropical regions. Investigation of this topic utilizes over 37 years of simulated global aerosol products from NASA atmospheric reanalysis, in the second Modern-Era Retrospective analysis for Research and Applications (MERRA-2) data set, available from NASA Goddard Earth Science Data and Information Services Center (GES DISC). MERRA-2 covers the period 1980-present, and is continuing as an ongoing climate analysis. Aerosol assimilation is included throughout the period, using data from MODIS, MISR, AERONET, and AVHRR (in the pre-EOS period). The aerosols are assimilated using the MERRA-2 aerosol model, which interacts directly with radiation parameterization, and is radiatively coupled with atmospheric model dynamics in the Goddard Earth Observing System Model, Version 5 (GEOS-5). Hourly, monthly, and monthly diurnal data are available at spatial resolution of 0.5o x 0.625o (latitude x longitude). By using MERRA-2 hourly and monthly diurnal products, different aerosol diurnal variabilities are observed over North America, Africa, Asia, and Australia, that may be due to different meteorological conditions and aerosol sources. The presentation will also provide an overview of MERRA-2 data services at GES DISC, such as how to find and download data, and how to quickly visualize and analyze data online with Giovanni.

  16. NASA and Dark Energy

    NASA Astrophysics Data System (ADS)

    Rhodes, Jason

    2014-03-01

    Dark energy, the name given to the cause of the accelerating expansion of the Universe, is one of the most profound mysteries in modern science. Current cosmological models hold that dark energy is currently the dominant component of the Universe, but the exact nature of dark energy remains poorly understood. There are ambitious ground-based surveys underway that seek to understand dark energy and NASA is participating in the development of significantly more ambitious space-based surveys planned for the next decade. NASA has provided mission enabling technology to the European Space Agency's (ESA) Euclid mission in exchange for US scientists to participate in the Euclid mission. NASA is also developing the Wide Field Infrared Survey Telescope-Astrophysics Focused Telescope Asset (WFIRST-AFTA) mission for possible launch in ~2023. WFIRST was the highest ranked space mission in the Astro2010 Decadal Survey and the AFTA incarnation of the WFIRST design uses a 2.4 m space telescope to go beyond what the Decadal Survey envisioned for WFIRST. Understanding dark energy is one of the primary science goals of WFIRST-AFTA. I'll discuss the status of Euclid and WFIRST and comment on the complementarity of the two missions.

  17. Advanced Methodologies for NASA Science Missions

    NASA Astrophysics Data System (ADS)

    Hurlburt, N. E.; Feigelson, E.; Mentzel, C.

    2017-12-01

    Most of NASA's commitment to computational space science involves the organization and processing of Big Data from space-based satellites, and the calculations of advanced physical models based on these datasets. But considerable thought is also needed on what computations are needed. The science questions addressed by space data are so diverse and complex that traditional analysis procedures are often inadequate. The knowledge and skills of the statistician, applied mathematician, and algorithmic computer scientist must be incorporated into programs that currently emphasize engineering and physical science. NASA's culture and administrative mechanisms take full cognizance that major advances in space science are driven by improvements in instrumentation. But it is less well recognized that new instruments and science questions give rise to new challenges in the treatment of satellite data after it is telemetered to the ground. These issues might be divided into two stages: data reduction through software pipelines developed within NASA mission centers; and science analysis that is performed by hundreds of space scientists dispersed through NASA, U.S. universities, and abroad. Both stages benefit from the latest statistical and computational methods; in some cases, the science result is completely inaccessible using traditional procedures. This paper will review the current state of NASA and present example applications using modern methodologies.

  18. NASA Engineer Jerry Elliott: Drawing from Two Worlds.

    ERIC Educational Resources Information Center

    Larson, Arwen

    1994-01-01

    Profiles Jerry Elliott, an American Indian who has taken advantage of both Native American and white cultures to become a successful engineer at NASA. He believes that Native Americans can meet the challenges of a modern world by studying science and engineering without losing their cultural identity and values. (LP)

  19. Education of the modern surgical resident: novel approaches to learning in the era of the 80-hour workweek.

    PubMed

    Nguyen, Liz; Brunicardi, F Charles; Dibardino, Daniel J; Scott, Bradford G; Awad, Samir S; Bush, Ruth L; Brandt, Mary L

    2006-06-01

    Implementation of the 80-hour work week has resulted in limitations on the hours available for resident education, creating a need for innovative approaches to teach surgical residents successfully. Herein we report the methods and results of an innovative didactic learning program at a large academic surgical residency program. Between 2004 and 2005, based on known principles of adult education and innovative learning techniques, a didactic learning program was instituted in a major academic surgery program. The course work consisted of a structured reading program using Schwartz's Textbook of Surgery, with weekly testing and problem-based learning (PBL) groups led by surgical faculty. The residents' progress was assessed by American Board of Surgery In-Training Examination (ABSITE) training scores before and after program implementation. A resident survey was also conducted to assess residents' attitudes toward the new program. Results were reported as a mean, and categoric variables were compared using a paired Student's t-test. During the academic year of the structured reading program, the mean ABSITE score improved by 10% (P=0.02) from the previous year. The postgraduate year 4 class had the largest change, with a score increase of 17% over the previous year's performance (P=0.02). Survey results demonstrated that 64% of the responders agreed that the small-group PBL was preferable for achieving educational goals. Furthermore, 89% of residents responded that the PBL groups improved interaction between residents and faculty members. An innovative formal learning program based on a major surgical textbook with weekly testing and small group sessions can significantly improve surgical training in the modern era of work-hour restrictions. Furthermore, surgical trainees find this format to be innovative and useful for improving didactic teaching.

  20. Vestibular schwannomas in the modern era: epidemiology, treatment trends, and disparities in management.

    PubMed

    Babu, Ranjith; Sharma, Richa; Bagley, Jacob H; Hatef, Jeffrey; Friedman, Allan H; Adamson, Cory

    2013-07-01

    There are a variety of treatment options for the management of vestibular schwannomas (VSs), including microsurgical resection, radiotherapy, and observation. Although the choice of treatment is dependent on various patient factors, physician bias has been shown to significantly affect treatment choice for VS. In this study the authors describe the current epidemiology of VS and treatment trends in the US in the modern era. They also illustrate patient and tumor characteristics and elucidate their effect on tumor management. Patients diagnosed with VS were identified through the Surveillance, Epidemiology, and End Results database, spanning the years 2004-2009. Age-adjusted incidence rates were calculated and adjusted using the 2000 US standard population. The chi-square and Student t-tests were used to evaluate differences between patient and tumor characteristics. Multivariate logistic regression was performed to determine the effects of various patient and tumor characteristics on the choice of tumor treatment. A total of 6225 patients with VSs treated between 2004 and 2009 were identified. The overall incidence rate was 1.2 per 100,000 population per year. The median age of patients with VS was 55 years, with the majority of patients being Caucasian (83.16%). Of all patients, 3053 (49.04%) received surgery only, with 1466 (23.55%) receiving radiotherapy alone. Both surgery and radiation were only used in 123 patients (1.98%), with 1504 patients not undergoing any treatment (24.16%). Increasing age correlated with decreased use of surgery (OR 0.95, 95% CI 0.95-0.96; p<0.0001), whereas increasing tumor size was associated with the increased use of surgery (OR 1.04, 95% CI 1.04-1.05; p<0.0001). Older age was associated with an increased likelihood of conservative management (OR 1.04, 95% CI 1.04-1.05; p<0.0001). Racial disparities were also seen, with African American patients being significantly less likely to receive surgical treatment compared with Caucasians

  1. Public health in New York City, 2002-2007: confronting epidemics of the modern era.

    PubMed

    Frieden, Thomas R; Bassett, Mary T; Thorpe, Lorna E; Farley, Thomas A

    2008-10-01

    Long after the leading causes of death in the United States shifted from infectious diseases to chronic diseases, many public health agencies have not established effective policies and programmes to prevent current health problems. Starting in 2002, the New York City health department, an agency with a long history of innovation, undertook initiatives to address chronic disease prevention and control, as well as to modernize methods to address persistent health problems. All the initiatives relied on an expansive use of epidemiology; actions to prevent disease were based on policy change to create health-promoting environments as well as engagement with the health care system to improve its focus on prevention. Examples of policy-based initiatives are: a multi-component tobacco control programme that included a tax increase, a comprehensive smoke-free air law, hard-hitting anti-tobacco advertising and cessation services; elimination of trans fats from restaurants and a mandate that restaurants post-calorie information on menu boards. Examples of health care initiatives are public health 'detailing' to primary care providers, creation of a city-wide diabetes registry and development of a public health-oriented electronic health record. The infrastructure needed by local health departments to prevent chronic diseases and other modern health problems includes strong information technology systems, skillful epidemiology, expertise in communications using modern media, policy-making authority and, most importantly, political support.

  2. NASA Project Develops Next-Generation Low-Emissions Combustor Technologies

    NASA Technical Reports Server (NTRS)

    Lee, Chi-Ming; Chang, Clarence T.; Herbon, John T.; Kramer, Stephen K.

    2013-01-01

    NASA's Environmentally Responsible Aviation (ERA) Project is working with industry to develop the fuel flexible combustor technologies for a new generation of low-emissions engine targeted for the 2020 timeframe. These new combustors will reduce nitrogen oxide (NOx) emissions to half of current state-of-the-art (SOA) combustors, while simultaneously reducing noise and fuel burn. The purpose of the low NOx fuel-flexible combustor research is to advance the Technology Readiness Level (TRL) and Integration Readiness Level (IRL) of a low NOx, fuel flexible combustor to the point where it can be integrated in the next generation of aircraft. To reduce project risk and optimize research benefit NASA chose to found two Phase 1 contracts. The first Phase 1 contracts went to engine manufactures and were awarded to: General Electric Company, and Pratt & Whitney Company. The second Phase 1 contracts went to fuel injector manufactures Goodrich Corporation, Parker Hannifin Corporation, and Woodward Fuel System Technology. In 2012, two sector combustors were tested at NASA's ASCR. The results indicated 75% NOx emission reduction below the 2004 CAEP/6 regulation level.

  3. Elementary Education and the Practices of Literacy in Catholic Girls' Schools in Early Modern Germany

    ERIC Educational Resources Information Center

    Rutz, Andreas

    2012-01-01

    Girls' schools in the early modern era were largely run by nuns and can therefore be distinguished as Catholic institutions of learning. These schools flourished in the Catholic parts of Europe since the turn of the seventeenth century. Despite their focus on religious education, elementary skills such as reading, writing and sometimes arithmetic…

  4. Status of NASA's Space Launch System

    NASA Technical Reports Server (NTRS)

    Honeycutt, John; Lyles, Garry

    2016-01-01

    NASA's Space Launch System (SLS) continued to make significant progress in 2015 and 2016, completing hardware and testing that brings NASA closer to a new era of deep space exploration. Programmatically, SLS completed Critical Design Review (CDR) in 2015. A team of independent reviewers concluded that the vehicle design is technically and programmatically ready to move to Design Certification Review (DCR) and launch readiness in 2018. Just five years after program start, every major element has amassed development and flight hardware and completed key tests that will lead to an accelerated pace of manufacturing and testing in 2016 and 2017. Key to SLS' rapid progress has been the use of existing technologies adapted to the new launch vehicle. The existing fleet of RS-25 engines is undergoing adaptation tests to prove it can meet SLS requirements and environments with minimal change. The four-segment shuttle-era booster has been modified and updated with a fifth propellant segment, new insulation, and new avionics. The Interim Cryogenic Upper Stage is a modified version of an existing upper stage. The first Block I SLS configuration will launch a minimum of 70 metric tons (t) of payload to low Earth orbit (LEO). The vehicle architecture has a clear evolutionary path to more than 100t and, ultimately, to 130t. Among the program's major 2015-2016 accomplishments were two booster qualification hotfire tests, a series of RS-25 adaptation hotfire tests, manufacturing of most of the major components for both core stage test articles and first flight tank, delivery of the Pegasus core stage barge, and the upper stage simulator. Renovations to the B-2 test stand for stage green run testing was completed at NASA Stennis Space Center. This year will see the completion of welding for all qualification and flight EM-1 core stage components and testing of flight avionics, completion of core stage structural test stands, casting of the EM-1 solid rocket motors, additional testing

  5. Status of NASA's Space Launch System

    NASA Technical Reports Server (NTRS)

    Honeycutt, John; Cook, Jerry; Lyles, Garry

    2016-01-01

    NASA's Space Launch System (SLS) continued to make significant progress in 2015, completing hardware and testing that brings NASA closer to a new era of deep space exploration. The most significant program milestone of the year was completion of Critical Design Review (CDR). A team of independent reviewers concluded that the vehicle design is technically and programmatically ready to move to Design Certification Review (DCR) and launch readiness in 2018. Just four years after program start, every major element has amassed development and flight hardware and completed key tests that will set the stage for a growing schedule of manufacturing and testing in 2016. Key to SLS' rapid progress has been the use of existing technologies adapted to the new launch vehicle. The space shuttle-heritage RS-25 engine is undergoing adaptation tests to prove it can meet SLS requirements and environments with minimal change. The four-segment shuttle-era booster has been modified and updated with an additional propellant segment, new insulation, and new avionics. The Interim Cryogenic Upper Stage is a modified version of an existing upper stage. The first Block I SLS configuration will launch a minimum of 70 metric tons of payload to low Earth orbit (LEO). The vehicle architecture has a clear evolutionary path to more than 100 metric tons and, ultimately, to 130 metric tons. Among the program's major accomplishments in 2015 were the first booster qualification hotfire test, a series of seven RS-25 adaptation hotfire tests, manufacturing of most of the major components for both core stage test articles and first flight tank, delivery of the Pegasus core stage barge, and the upper stage simulator. Renovations to the B-2 test stand for stage green run testing was completed at NASA Stennis Space Center. This year will see the second booster qualification motor hotfire, flight and additional development RS-25 engine tests, and completion of core stage test articles and test stands and

  6. Status of NASA's Space Launch System

    NASA Technical Reports Server (NTRS)

    Lyles, Garry

    2016-01-01

    NASA's Space Launch System (SLS) continued to make significant progress in 2015, completing hardware and testing that brings NASA closer to a new era of deep space exploration. The most significant program milestone of the year was completion of Critical Design Review (CDR). A team of independent reviewers concluded that the vehicle design is technically and programmatically ready to move to Design Certification Review (DCR) and launch readiness in 2018. Just four years after program start, every major element has amassed development and flight hardware and completed key tests that will set the stage for a growing schedule of manufacturing and testing in 2016. Key to SLS' rapid progress has been the use of existing technologies adapted to the new launch vehicle. The space shuttle-heritage RS-25 engine is undergoing adaptation tests to prove it can meet SLS requirements and environments with minimal change. The four-segment shuttle-era booster has been modified and updated with an additional propellant segment, new insulation, and new avionics. The Interim Cryogenic Upper Stage is a modified version of an existing upper stage. The first Block I SLS configuration will launch a minimum of 70 metric tons (t) of payload to low Earth orbit (LEO). The vehicle architecture has a clear evolutionary path to more than 100t and, ultimately, to 130t. Among the program's major accomplishments in 2015 were the first booster qualification hotfire test, a series of seven RS-25 adaptation hotfire tests, manufacturing of most of the major components for both core stage test articles and first flight tank, delivery of the Pegasus core stage barge, and the upper stage simulator. Renovations to the B-2 test stand for stage green run testing was completed at NASA Stennis Space Center. This year will see the second booster qualification motor hotfire, flight and additional development RS-25 engine tests, and completion of core stage test articles and test stands and several flight article

  7. Status of ERA Airframe Technology Demonstrators

    NASA Technical Reports Server (NTRS)

    Davis, Pamela; Jegley, Dawn; Rigney, Tom

    2015-01-01

    NASA has created the Environmentally Responsible Aviation (ERA) Project to explore and document the feasibility, benefits and technical risk of advanced vehicle configurations and enabling technologies that will reduce the impact of aviation on the environment. A critical aspect of this pursuit is the development of a lighter, more robust airframe that will enable the introduction of unconventional aircraft configurations that have higher lift-to-drag ratios, reduced drag, and lower community noise. The Airframe Technology subproject contains two elements. Under the Damage Arresting Composite Demonstration an advanced material system is being explored which will lead to lighter airframes that are more structural efficient than the composites used in aircraft today. Under the Adaptive Compliant Trailing Edge Flight Experiment a new concept of a flexible wing trailing edge is being evaluated which will reduce weight and improve aerodynamic performance. This presentation will describe the development these two airframe technologies.

  8. Are we ready for the ERAS protocol in colorectal surgery?

    PubMed

    Kisielewski, Michał; Rubinkiewicz, Mateusz; Pędziwiatr, Michał; Pisarska, Magdalena; Migaczewski, Marcin; Dembiński, Marcin; Major, Piotr; Rembiasz, Kazimierz; Budzyński, Andrzej

    2017-01-01

    Modern perioperative care principles in elective colorectal surgery have already been established by international surgical authorities. Nevertheless, barriers to the introduction of routine evidence-based clinical care and changing dogmas still exist. One of the factors is the surgeon. To assess perioperative care trends in elective colorectal surgery among general surgery consultants in surgical departments in Malopolska Voivodeship, Poland. An anonymous standardized 20-question questionnaire was developed based on ERAS principles and sent out to Malopolska Voivodeship general surgery departments. Answers of general surgery consultants showed the level of acceptance of elements of perioperative care. The overall response rate was 66%. Several elements (antibiotic and antithrombotic prophylaxis, postoperative oxygen therapy, no nasogastric tubes) had quite a high acceptance rate. On the other hand, most crucial surgical perioperative elements (lack of mechanical bowel preparation, preoperative oral carbohydrate loading, use of laparoscopy and lack of drains, early fluid and oral diet intake, early mobilization) were not followed according to evidence-based ERAS protocol recommendations. Surgeons were not willing to change their practice, but were supportive of changes in anesthesiologist-dependent elements of perioperative care, such as restrictive fluid therapy, use of transversus abdominis plane blocks, etc. Many elements of perioperative care in elective colorectal surgery in Malopolska Voivodeship are still dictated by dogma and are not evidence-based. The level of acceptance of many important ERAS protocol elements is low. Surgeons are ready to accept only changes that do not interfere with their practice.

  9. Vision 21: Interdisciplinary Science and Engineering in the Era of Cyberspace

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The symposium Vision-21: Interdisciplinary Science and Engineering in the Era of Cyberspace was held at the NASA Lewis Research Center on March 30-31, 1993. The purpose of the symposium was to simulate interdisciplinary thinking in the sciences and technologies which will be required for exploration and development of space over the next thousand years. The keynote speakers were Hans Moravec, Vernor Vinge, Carol Stoker, and Myron Krueger. The proceedings consist of transcripts of the invited talks and the panel discussion by the invited speakers, summaries of workshop sessions, and contributed papers by the attendees.

  10. The Modern Intercultural Persona and "Civitas": Tracing the Path Back to the Ancient Greek Demoi

    ERIC Educational Resources Information Center

    Palaiologou, Nektaria

    2011-01-01

    This conceptual paper represents an attempt to reflect on the notion of the "ancient Greek polis"--a subject of study and sometimes heated debate for many philosophers and historians worldwide--as a paradigm of a city that can offer some insight into modern states, in an era of globalisation and tense multiculturalism. By providing a…

  11. The NASA Dryden Flight Test Approach to an Aerial Refueling System

    NASA Technical Reports Server (NTRS)

    Hansen, Jennifer L.; Murray, James E.; Campos, Norma V.

    2005-01-01

    The integration of uninhabited aerial vehicles (UAVs) into controlled airspace has generated a new era of autonomous technologies and challenges. Autonomous aerial refueling would enable UAVs to travel further distances and loiter for extended periods over time-critical targets. The NASA Dryden Flight Research Center recently has completed a flight research project directed at developing a dynamic hose and drogue system model to support the development of an automated aerial refueling system. A systematic dynamic model of the hose and drogue system would include the effects of various influences on the system, such as flight condition, hose and drogue type, tanker type and weight, receiver type, and tanker and receiver maneuvering. Using two NASA F/A-18 aircraft and a conventional hose and drogue aerial refueling store from the Navy, NASA has obtained flight research data that document the response of the hose and drogue system to these effects. Preliminary results, salient trends, and important lessons are presented

  12. NASA Historical Data Book. Volume 5; NASA Launch Systems, Space Transportation, Human Spaceflight and Space Science, 1979-1988

    NASA Technical Reports Server (NTRS)

    Rumerman, Judy A. (Compiler)

    1999-01-01

    In 1973, NASA published the first volume of the NASA Historical Data Book, a hefty tome containing mostly tabular data on the resources of the space agency between 1958 and 1968. There, broken into detailed tables, were the facts and figures associated with the budget, facilities, procurement, installations, and personnel of NASA during that formative decade. In 1988, NASA reissued that first volume of the data book and added two additional volumes on the agency's programs and projects, one each for 1958-1968 and 1969-1978. NASA published a fourth volume in 1994 that addressed NASA resources for the period between 1969 and 1978. This fifth volume of the NASA Historical Data Book is a continuation of those earlier efforts. This fundamental reference tool presents information, much of it statistical, documenting the development of four critical areas of NASA responsibility for the period between 1979 and 1988. This volume includes detailed information on the development and operation of launch systems, space transportation, human spaceflight, and space science during this era. As such, it contains in-depth statistical information about the early Space Shuttle program through the return to flight in 1988, the early efforts to build a space station, the development of new launch systems, and the launching of seventeen space science missions. A companion volume will appear late in 1999, documenting the space applications, support operations, aeronautics, and resources aspects of NASA during the period between 1979 and 1988. NASA began its operations as the nation's civilian space agency in 1958 following the passage of the National Aeronautics and Space Act. It succeeded the National Advisory Committee for Aeronautics (NACA). The new organization was charged with preserving the role of the United States "as a leader in aeronautical and space science and technology" and in its application, with expanding our knowledge of the Earth's atmosphere and space, and with

  13. The NOAA-NASA CZCS Reanalysis Effort

    NASA Technical Reports Server (NTRS)

    Gregg, Watson W.; Conkright, Margarita E.; OReilly, John E.; Patt, Frederick S.; Wang, Meng-Hua; Yoder, James; Casey-McCabe, Nancy; Koblinsky, Chester J. (Technical Monitor)

    2001-01-01

    Satellite observations of global ocean chlorophyll span over two decades. However, incompatibilities between processing algorithms prevent us from quantifying natural variability. We applied a comprehensive reanalysis to the Coastal Zone Color Scanner (CZCS) archive, called the NOAA-NASA CZCS Reanalysis (NCR) Effort. NCR consisted of 1) algorithm improvement (AI), where CZCS processing algorithms were improved using modernized atmospheric correction and bio-optical algorithms, and 2) blending, where in situ data were incorporated into the CZCS AI to minimize residual errors. The results indicated major improvement over the previously available CZCS archive. Global spatial and seasonal patterns of NCR chlorophyll indicated remarkable correspondence with modern sensors, suggesting compatibility. The NCR permits quantitative analyses of interannual and interdecadal trends in global ocean chlorophyll.

  14. Engineering Education for a New Era

    NASA Astrophysics Data System (ADS)

    Ohgaki, Shinichiro

    Engineering education is composed of five components, the idea what engineering education ought to be, the knowledge in engineering fields, those who learn engineering, those who teach engineering and the stakeholders in engineering issues. The characteristics of all these five components are changing with the times. When we consider the engineering education for the next era, we should analyze the changes of all five components. Especially the knowledge and tools in engineering fields has been expanding, and advanced science and technology is casting partly a dark shadow on the modern convenient life. Moral rules or ethics for developing new products and engineering systems are now regarded as most important in engineering fields. All those who take the responsibility for engineering education should understand the change of all components in engineering education and have a clear grasp of the essence of engineering for sustainable society.

  15. [The Paduan School of Medicine: medicine and philosophy in the modern era].

    PubMed

    Rebollo, Regina Andrés

    2010-06-01

    This is a partial contribution to an understanding of the history of the reception and transmission of classical Hippocratic and Galenic texts in Italy's modern period. By examining rotuli and puncti of the School of Medicine of Padua University, which record the subjects and content taught in the period between 1500 and 1600, one can study the official curriculum of this famous school. Perusal of these documents shows the commitment of official medical training to tradition, especially with respect to Hippocrates, Galen, Avicenna and Aristotle.

  16. 2016 Summer Series - Jin-Woo Han: Vacuum Electronics in a Nanometer Era

    NASA Image and Video Library

    2016-06-07

    Modern space vehicles rely on transistors. Radiation tolerance of space electronics is critical for space exploration beyond low Earth orbit. NASA Ames Research Center is investigating ways to overcome this issue using vacuums. Dr. Jin-Woo Han's lecture will present advancements in the use of vacuums to improve radiation immunity in space circuitry.

  17. Lunar paleomagnetism: a new analysis of the Apollo-era paleomagnetic measurements

    NASA Astrophysics Data System (ADS)

    Fuller, M.; Weiss, B. P.

    2011-12-01

    The Apollo era lunar paleomagnetism suffered from the lack of modern instrumentation and data analysis techniques. However, paleomagnetic data for nearly 100 samples were reported. We have completed a reanalysis of these old Apollo paleomagnetic data using modern techniques of analysis. The principal result from the mare basalts is that many samples such as 10020, 10017, 10049, 12022, and 70215 appear to be carrying primary natural remanent magnetization (NRM) acquired on the Moon as they initially cooled on the lunar surface, but in almost every case alternating field (AF) demagnetization was not carried out to strong enough fields to isolate this primary magnetization properly. When modern measurements are available, the agreement between old Apollo era data and new data is strikingly good. It also appears that the fields recorded by the basalts of Apollo 11 and Apollo 17 may be stronger than those recorded by Apollo 12 basalts, but the small number of high fidelity magnetic recorders among the latter group make this tentative at present. The histories of breccias are more complicated than those of mare basalts and their NRM is harder to interpret. The regolith and fragmental breccias have NRM, which is either a combination of shock remanent magnetization (SRM) acquired during shock lithification and partial to total thermal remanent magnetization (TRM) depending upon the residual temperature after the shock event. For regolith breccias, interpretations are complicated because of their strong superparamagnetic components and their complex, polymict lithologies. It would be unwise to use these samples for paleointensity estimates unless one can be sure that the NRM was entirely acquired as TRM during cooling after the shock event, such as may be the case for 15498. In contrast, the melt rock and melt breccias, which are formed at high temperatures far above the Curie point of any magnetic carriers, have an excellent chance of recording lunar fields faithfully when

  18. The Green Monster: Stokes's 1944 Modern Clinical Syphilology.

    PubMed

    Jackson, Robert

    2010-01-01

    There is much information on the life and accomplishments of John Hinchman Stokes (1885-1961), the dermatologist and syphilologist. There is little detailed information on his 1944 classic text on syphilis, Modern Clinical Syphilology. To review and critique this book. A careful review of the book, his life, and the accomplishments that were undertaken in relation to the age in which he lived. The book is indeed a goldmine of information of all aspects of syphilis from pre-World War I (1905) until the late (1944) World War II era. The factors that make it a classic are as follows: (1) the disease had a specific cause; (2) Stokes's 25-year obsession with the disease; (3) there was no effective simple cure for most of the time he was studying it; (4) Stokes was an obsessive, intelligent, well-trained physician; (5) he lived in a well-developed, reasonably stable country; and (6) he was able to see how the disease could be adequately treated with penicillin and compare these events with those in the prepenicillin era.

  19. Seasonal scale water deficit forecasting in Africa and the Middle East using NASA's Land Information System (LIS)

    NASA Astrophysics Data System (ADS)

    Peters-Lidard, C. D.; Arsenault, K. R.; Shukla, S.; Getirana, A.; McNally, A.; Koster, R. D.; Zaitchik, B. F.; Badr, H. S.; Roningen, J. M.; Kumar, S.; Funk, C. C.

    2017-12-01

    A seamless and effective water deficit monitoring and early warning system is critical for assessing food security in Africa and the Middle East. In this presentation, we report on the ongoing development and validation of a seasonal scale water deficit forecasting system based on NASA's Land Information System (LIS) and seasonal climate forecasts. First, our presentation will focus on the implementation and validation of drought and water availability monitoring products in the region. Next, it will focus on evaluating drought and water availability forecasts. Finally, details will be provided of our ongoing collaboration with end-user partners in the region (e.g., USAID's Famine Early Warning Systems Network, FEWS NET), on formulating meaningful early warning indicators, effective communication and seamless dissemination of the products through NASA's web-services. The water deficit forecasting system thus far incorporates NASA GMAO's Catchment and the Noah Multi-Physics (MP) LSMs. In addition, the LSMs' surface and subsurface runoff are routed through the Hydrological Modeling and Analysis Platform (HyMAP) to simulate surface water dynamics. To establish a climatology from 1981-2015, the two LSMs are driven by NASA/GMAO's Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2), and the USGS and UCSB Climate Hazards Group InfraRed Precipitation with Station (CHIRPS) daily rainfall dataset. Comparison of the models' energy and hydrological budgets with independent observations suggests that major droughts are well-reflected in the climatology. The system uses seasonal climate forecasts from NASA's GEOS-5 (the Goddard Earth Observing System Model-5) and NCEP's Climate Forecast System-2, and it produces forecasts of soil moisture, ET and streamflow out to 6 months in the future. Forecasts of those variables are formulated in terms of indicators to provide forecasts of drought and water availability in the region. Current work suggests

  20. Atherosclerosis in ancient and modern Egyptians: the Horus study.

    PubMed

    Allam, Adel H; Mandour Ali, Mohamed A; Wann, L Samuel; Thompson, Randall C; Sutherland, M Linda; Sutherland, James D; Frohlich, Bruno; Michalik, David E; Zink, Albert; Lombardi, Guido P; Watson, Lucia; Cox, Samantha L; Finch, Caleb E; Miyamoto, Michael I; Sallam, Sallam L; Narula, Jagat; Thomas, Gregory S

    2014-06-01

    Although atherosclerosis is usually thought of as a disease of modernity, the Horus Team has previously reported atherosclerotic vascular calcifications on computed tomographic (CT) scans in ancient Egyptians. The purpose of this study was to compare patterns and demographic characteristics of this disease among Egyptians from ancient and modern eras. We compared the presence and extent of vascular calcifications from whole-body CT scans performed on 178 modern Egyptians from Cairo undergoing positron emission tomography (PET)/CT for cancer staging to CT scans of 76 Egyptian mummies (3100 bce to 364 ce). The mean age of the modern Egyptian group was 52.3 ± 15 years (range 14 to 84) versus estimated age at death of ancient Egyptian mummies 36.5 ± 13 years (range 4 to 60); p < 0.0001. Vascular calcification was detected in 108 of 178 (60.7%) of modern patients versus 26 of 76 (38.2%) of mummies, p < 0.001. Vascular calcifications on CT strongly correlated to age in both groups. In addition, the severity of disease by number of involved arterial beds also correlated to age, and there was a very similar pattern between the 2 groups. Calcifications in both modern and ancient Egyptians were seen peripherally in aortoiliac beds almost a decade earlier than in event-related beds (coronary and carotid). The presence and severity of atherosclerotic vascular disease correlates strongly to age in both ancient and modern Egyptians. There is a striking correlation in the distribution of the number of vascular beds involved. Atherosclerotic calcifications are seen in the aortoiliac beds almost a decade earlier than in the coronary and carotid beds. Copyright © 2014. Published by Elsevier B.V.

  1. Cecal intubation rates in different eras of endoscopic technological development.

    PubMed

    Matyja, Maciej; Pasternak, Artur; Szura, Mirosław; Pędziwiatr, Michał; Major, Piotr; Rembiasz, Kazimierz

    2018-03-01

    Colonoscopy plays a critical role in colorectal cancer (CRC) screening and has been widely regarded as the gold standard. Cecal intubation rate (CIR) is one of the well-defined quality indicators used to assess colonoscopy. To assess the impact of new technologies on the quality of colonoscopy by assessing completion rates. This was a dual-center study at the 2 nd Department of Surgery at Jagiellonian University Medical College and at the Specialist Center "Medicina" in Krakow, Poland. The CIR and cecal intubation time (CIT) in three different eras of technological advancement were determined. The study enrolled 27 463 patients who underwent colonoscopy as part of a national CRC screening program. The patients were divided into three groups: group I - 3408 patients examined between 2000 and 2003 (optical endoscopes); group II - 10 405 patients examined between 2004 and 2008 (standard electronic endoscopes); and group III - 13 650 patients examined between 2009 and 2014 (modern endoscopes). There were statistically significant differences in the CIR between successive eras. The CIR in group I (2000-2003) was 69.75%, in group II (2004-2008) was 92.32%, and in group III (2009-2014) was 95.17%. The mean CIT was significantly reduced in group III. Our study shows that the technological innovation of novel endoscopy devices has a great influence on the effectiveness of the CRC screening program. The new era of endoscopic technological development has the potential to reduce examination-related patient discomfort, obviate the need for sedation and increase diagnostic yields.

  2. "None Must Meddle Betueene Man and Wife": assessing family and the fluidity of public and private in early modern Scotland.

    PubMed

    Nugent, Janay

    2010-01-01

    The physical and ideological boundaries between public and private in early modern Scotland were constantly contested, resulting in a shifting reality of what was public and private. This fluidity has been recognized by historians, but how, when, and why the shifting took place is not as clear. The moral church courts (Kirk Sessions) of Reformation Scotland allow a unique opportunity to begin to understand the largely elusive boundaries between public and private in the early modern era.

  3. Exploring Climatology and Long-Term Variations of Aerosols from NASA Reanalysis MERRA-2 with Giovanni

    NASA Technical Reports Server (NTRS)

    Shen, Suhung; Ostrenga, Dana; Vollmer, Bruce; Li, Zhanqing

    2016-01-01

    Dust plays important roles in energy cycle and climate variations. The dust deposition is the major source of iron in the open ocean, which is an essential micronutrient for phytoplankton growth and therefore may influence the ocean uptake of atmospheric CO2. Mineral dust can also act as fertilizer for forests over long time periods. Over 35 years of simulated global aerosol products from NASA atmospheric reanalysis, second Modern-Era Retrospective analysis for Research and Applications (MERRA-2) are available from NASA Goddard Earth Science Data and Information Services Center (GES DISC). The MERRA-2 covers the period 1980-present, continuing as an ongoing climate analysis. Aerosol assimilation is included throughout the period, using MODIS, MISR, AERONET, and AVHRR (in the pre-EOS period). The aerosols are assimilated by using MERRA-2 aerosol model, which interact directly with the radiation parameterization, and radiatively coupled with atmospheric model dynamics in the Goddard Earth Observing System Model, Version 5 (GEOS-5). Dust deposition data along with other major aerosol compositions (e.g. black carbon, sea salt, and sulfate, etc.) are simulated as dry and wet deposition, respectively. The hourly and monthly data are available at spatial resolution of 0.5ox0.625o (latitude x longitude). Quick data exploration of climatology and interannual variations of MERRA-2 aerosol can be done through the online visualization and analysis tool, Giovanni. This presentation, using dust deposition as an example, demonstrates a number of MERRA-2 data services at GES DISC. Global distributions of dust depositions, and their seasonal and inter-annual variations are investigated from MERRA-2 monthly aerosol products.

  4. Investments by NASA to build planetary protection capability

    NASA Astrophysics Data System (ADS)

    Buxbaum, Karen; Conley, Catharine; Lin, Ying; Hayati, Samad

    NASA continues to invest in capabilities that will enable or enhance planetary protection planning and implementation for future missions. These investments are critical to the Mars Exploration Program and will be increasingly important as missions are planned for exploration of the outer planets and their icy moons. Since the last COSPAR Congress, there has been an opportunity to respond to the advice of NRC-PREVCOM and the analysis of the MEPAG Special Regions Science Analysis Group. This stimulated research into such things as expanded bioburden reduction options, modern molecular assays and genetic inventory capability, and approaches to understand or avoid recontamination of spacecraft parts and samples. Within NASA, a portfolio of PP research efforts has been supported through the NASA Office of Planetary Protection, the Mars Technology Program, and the Mars Program Office. The investment strategy focuses on technology investments designed to enable future missions and reduce their costs. In this presentation we will provide an update on research and development supported by NASA to enhance planetary protection capability. Copyright 2008 California Institute of Technology. Government sponsorship acknowledged.

  5. Building Knowledge Graphs for NASA's Earth Science Enterprise

    NASA Astrophysics Data System (ADS)

    Zhang, J.; Lee, T. J.; Ramachandran, R.; Shi, R.; Bao, Q.; Gatlin, P. N.; Weigel, A. M.; Maskey, M.; Miller, J. J.

    2016-12-01

    Inspired by Google Knowledge Graph, we have been building a prototype Knowledge Graph for Earth scientists, connecting information and data in NASA's Earth science enterprise. Our primary goal is to advance the state-of-the-art NASA knowledge extraction capability by going beyond traditional catalog search and linking different distributed information (such as data, publications, services, tools and people). This will enable a more efficient pathway to knowledge discovery. While Google Knowledge Graph provides impressive semantic-search and aggregation capabilities, it is limited to search topics for general public. We use the similar knowledge graph approach to semantically link information gathered from a wide variety of sources within the NASA Earth Science enterprise. Our prototype serves as a proof of concept on the viability of building an operational "knowledge base" system for NASA Earth science. Information is pulled from structured sources (such as NASA CMR catalog, GCMD, and Climate and Forecast Conventions) and unstructured sources (such as research papers). Leveraging modern techniques of machine learning, information retrieval, and deep learning, we provide an integrated data mining and information discovery environment to help Earth scientists to use the best data, tools, methodologies, and models available to answer a hypothesis. Our knowledge graph would be able to answer questions like: Which articles discuss topics investigating similar hypotheses? How have these methods been tested for accuracy? Which approaches have been highly cited within the scientific community? What variables were used for this method and what datasets were used to represent them? What processing was necessary to use this data? These questions then lead researchers and citizen scientists to investigate the sources where data can be found, available user guides, information on how the data was acquired, and available tools and models to use with this data. As a proof of

  6. The Application of NASA Technology to Public Health

    NASA Technical Reports Server (NTRS)

    Rickman, Douglas L.; Watts, C.

    2007-01-01

    NASA scientists have a history of applying technologies created to handle satellite data to human health at various spatial scales. Scientists are now engaged in multiple public health application projects that integrate NASA satellite data with measures of public health. Such integration requires overcoming disparities between the environmental and the health data. Ground based sensors, satellite imagery, model outputs and other environmental sources have inconsistent spatial and temporal distributions. The MSFC team has recognized the approach used by environmental scientists to fill in the empty places can also be applied to outcomes, exposures and similar data. A revisit to the classic epidemiology study of 1854 using modern day surface modeling and GIS technology, demonstrates how spatial technology can enhance and change the future of environmental epidemiology. Thus, NASA brings to public health, not just a set of data, but an innovative way of thinking about the data.

  7. Childhood chronic inflammatory demyelinating polyneuropathy: an overview of 10 cases in the modern era.

    PubMed

    Ware, Tyson L; Kornberg, Andrew J; Rodriguez-Casero, M Victoria; Ryan, Monique M

    2014-01-01

    Chronic inflammatory demyelinating polyneuropathy is a rare condition in children. In this article, we report our experience in the management of 10 cases of childhood chronic inflammatory demyelinating polyneuropathy in a single center, in the era of contrast-enhanced magnetic resonance imaging (MRI), genetic microarray, and chronic inflammatory demyelinating polyneuropathy disease activity status. Robust neurophysiologic abnormalities were present in all cases and both MRI and lumbar puncture were useful adjuncts in diagnosis. Genetic microarray is a simple technique useful in excluding the most common hereditary demyelinating neuropathy. Intravenous immunoglobulin was an effective first-line therapy in most cases, with refractory cases responding to corticosteroids and rituximab. We found the chronic inflammatory demyelinating polyneuropathy disease activity status useful for assessing outcome at final follow-up, whereas the modified Rankin score was better for assessing peak motor disability.

  8. ERA-MIN: The European network (ERA-NET) on non-energy raw materials

    NASA Astrophysics Data System (ADS)

    vidal, o.; christmann, p.; Bol, d.; Goffé, b.; Groth, m.; Kohler, e.; Persson Nelson, k.; Schumacher, k.

    2012-04-01

    Non-energy raw materials are vital for the EU's economy, and for the development of environmentally friendly technologies. The EU is the world's largest consumers of non-energy minerals, but it remains dependent on the importation of many metals, as its domestic production is limited to about 3% of world production. We will present the project ERA-MIN, which is an ERA-NET on the Industrial Handling of Raw Materials for European industries, financially supported by the European Commission. The main objectives of ERA-MIN are: 1) Mapping and Networking: interconnecting the members of the currently fragmented European mineral resources research area, to the aim of fostering convergence of public research programs, industry, research institutes, academia and the European Commission, 2) Coordinating: establishing a permanent mechanism for planning and coordination of the European non-energy mineral raw materials research community (ENERC). 3) Roadmapping: defining the most important scientific and technological challenges that should be supported by the EU and its state members, 4) Programming: designing a Joint European Research Programme model and implementating it into a call for proposals open to academic and industrial research. The topics of interest in ERA-MIN are the primary continental and marine resources, the secondary resources and their related technologies, substitution and material efficiency, along with transversal topics such as environmental impact, public policy support, mineral intelligence, and public education and teaching. Public scientific research is very central in the scope of the ERA-MIN activity, whose consortium is indeed lead by a public organisation of fundamental research. Thus, universities and public research organisations are warmly invited to play an active role in defining the scientific questions and challenges that shall determine the European Raw Materials Roadmap and should be addressed by joint programming at the European scale

  9. Vintage meets contemporary: Use of rigid TBNA in the era of real-time imaging - first report from India.

    PubMed

    Khan, Ajmal; Nath, Alok; Lal, Hira; Krishnani, Narendra; Agarwal, Aarti

    2018-01-01

    In the modern era, real-time imaging-guided transbronchial needle aspiration (TBNA) has completely replaced the traditional surgical approaches to sample the mediastinal lesions for diagnosis and cancer staging. However, there is a limited role of these innovations in the presence of critical airway narrowing due to a further decrease in cross-sectional area of the airway proportionate to the outer diameters of the scope. Rigid TBNA with airway control by rigid bronchoscopy is one alternative which can be used for mediastinal sampling when modern technique is impracticable. Herein, we report the use of rigid TBNA, an underutilized old method to sample the mediastinal lesion in a patient with severe orthopnea secondary to tracheal compression by mediastinal mass.

  10. Kickstarting a New Era of Lunar Industrialization via Campaign of Lunar COTS Missions

    NASA Technical Reports Server (NTRS)

    Zuniga, Allison F.; Turner, Mark; Rasky, Daniel; Pittman, Robert B.; Zapata, Edgar

    2016-01-01

    To support the goals of expanding our human presence and current economic sphere beyond LEO, a new plan was constructed for NASA to enter into partnerships with industry to foster and incentivize a new era of lunar industrialization. For NASA to finally be successful in achieving sustainable human exploration missions beyond LEO, lessons learned from our space history have shown that it is essential for current program planning to include affordable and economic development goals as well as address top national priorities to obtain much needed public support. In the last 58 years of NASA's existence, only Apollo's human exploration missions beyond LEO were successful since it was proclaimed to be a top national priority during the 1960's. However, the missions were not sustainable and ended abruptly in 1972 due to lack of funding and insufficient economic gain. Ever since Apollo, there have not been any human missions beyond LEO because none of the proposed program plans were economical or proclaimed a top national priority. The proposed plan outlines a new campaign of low-cost, commercial-enabled lunar COTS (Commercial Orbital Transfer Services) missions which is an update to the Lunar COTS plan previously described. The objectives of this new campaign of missions are to prospect for resources, determine the economic viability of extracting those resources and assess the value proposition of using these resources in future exploration architectures such as Mars. These missions would be accomplished in partnership with commercial industry using the wellproven COTS Program acquisition model. This model proved to be very beneficial to both NASA and its industry partners as NASA saved significantly in development and operational costs, as much as tenfold, while industry partners successfully expanded their market share and demonstrated substantial economic gain. Similar to COTS, the goals for this new initiative are 1) to develop and demonstrate cost-effective, cis

  11. Supporting EarthScope Cyber-Infrastructure with a Modern GPS Science Data System

    NASA Astrophysics Data System (ADS)

    Webb, F. H.; Bock, Y.; Kedar, S.; Jamason, P.; Fang, P.; Dong, D.; Owen, S. E.; Prawirodirjo, L.; Squibb, M.

    2008-12-01

    Building on NASA's investment in the measurement of crustal deformation from continuous GPS, we are developing and implementing a Science Data System (SDS) that will provide mature, long-term Earth Science Data Records (ESDR's). This effort supports NASA's Earth Surface and Interiors (ESI) focus area and provide NASA's component to the EarthScope PBO. This multi-year development is sponsored by NASA's Making Earth System data records for Use in Research Environments (MEaSUREs) program. The SDS integrates the generation of ESDRs with data analysis and exploration, product generation, and modeling tools based on daily GPS data that include GPS networks in western North America and a component of NASA's Global GPS Network (GGN) for terrestrial reference frame definition. The system is expandable to multiple regional and global networks. The SDS builds upon mature data production, exploration, and analysis algorithms developed under NASA's REASoN, ACCESS, and SENH programs. This SDS provides access to positions, time series, velocity fields, and strain measurements derived from continuous GPS data obtained at tracking stations in both the Plate Boundary Observatory and other regional Western North America GPS networks, dating back to 1995. The SDS leverages the IT and Web Services developments carried out under the SCIGN/REASoN and ACCESS projects, which have streamlined access to data products for researchers and modelers, and which have created a prototype an on-the-fly interactive research environment through a modern data portal, GPS Explorer. This IT system has been designed using modern IT tools and principles in order to be extensible to any geographic location, scale, natural hazard, and combination of geophysical sensor and related data. We have built upon open GIS standards, particularly those of the OGC, and have used the principles of Web Service-based Service Oriented Architectures to provide scalability and extensibility to new services and capabilities.

  12. Cecal intubation rates in different eras of endoscopic technological development

    PubMed Central

    Pasternak, Artur; Szura, Mirosław; Pędziwiatr, Michał; Major, Piotr; Rembiasz, Kazimierz

    2018-01-01

    Introduction Colonoscopy plays a critical role in colorectal cancer (CRC) screening and has been widely regarded as the gold standard. Cecal intubation rate (CIR) is one of the well-defined quality indicators used to assess colonoscopy. Aim To assess the impact of new technologies on the quality of colonoscopy by assessing completion rates. Material and methods This was a dual-center study at the 2nd Department of Surgery at Jagiellonian University Medical College and at the Specialist Center “Medicina” in Krakow, Poland. The CIR and cecal intubation time (CIT) in three different eras of technological advancement were determined. The study enrolled 27 463 patients who underwent colonoscopy as part of a national CRC screening program. The patients were divided into three groups: group I – 3408 patients examined between 2000 and 2003 (optical endoscopes); group II – 10 405 patients examined between 2004 and 2008 (standard electronic endoscopes); and group III – 13 650 patients examined between 2009 and 2014 (modern endoscopes). Results There were statistically significant differences in the CIR between successive eras. The CIR in group I (2000–2003) was 69.75%, in group II (2004–2008) was 92.32%, and in group III (2009–2014) was 95.17%. The mean CIT was significantly reduced in group III. Conclusions Our study shows that the technological innovation of novel endoscopy devices has a great influence on the effectiveness of the CRC screening program. The new era of endoscopic technological development has the potential to reduce examination-related patient discomfort, obviate the need for sedation and increase diagnostic yields. PMID:29643961

  13. The Vietnam Era Veteran: Challenge for Change. Administrator's Seminars on Vietnam Era Veterans.

    ERIC Educational Resources Information Center

    Veterans Administration, Washington, DC.

    This report covers 5 regional seminars designed to increase the Veterans Administration understanding of Vietnam Era veterans. The process used was one of involvement and interaction of Veterans Administration officials with returning Vietnam Era veterans and other young people. After the traditional introductions and keynote remarks, there was a…

  14. Using NASA-Unique Lunar Sample Disks and Resources to Inspire and Promote Scientific Inquiry

    NASA Technical Reports Server (NTRS)

    Allen, J.; Graff, P. V.; Willis, K. J.; Runco, S.

    2014-01-01

    The opportunity for educators and students across the nation to hold precious, NASA lunar samples in their hands and examine materials brought back by astronauts during the Apollo era is an experience and memory that can last a lifetime. Combine that experience with the opportunity to be engaged with hands-on activities that promote scientific inquiry and an understanding of the importance of these samples...now you are preparing our nation's future scientific explorers.

  15. Development of real-time software environments for NASA's modern telemetry systems

    NASA Technical Reports Server (NTRS)

    Horner, Ward; Sabia, Steve

    1989-01-01

    An effort has been made to maintain maximum performance and flexibility for NASA-Goddard's VLSI telemetry system elements through the development of two real-time systems: (1) the Base System Environment, which supports generic system integration and furnishes the basic porting of various manufacturers' cards, and (2) the Modular Environment for Data Systems, which supports application-specific developments and furnishes designers with a set of tested generic library functions that can be employed to speed up the development of such application-specific real-time codes. The performance goals and design rationale for these two systems are discussed.

  16. NASA's Propulsion Research Laboratory

    NASA Technical Reports Server (NTRS)

    2004-01-01

    The grand opening of NASA's new, world-class laboratory for research into future space transportation technologies located at the Marshall Space Flight Center (MSFC) in Huntsville, Alabama, took place in July 2004. The state-of-the-art Propulsion Research Laboratory (PRL) serves as a leading national resource for advanced space propulsion research. Its purpose is to conduct research that will lead to the creation and development of innovative propulsion technologies for space exploration. The facility is the epicenter of the effort to move the U.S. space program beyond the confines of conventional chemical propulsion into an era of greatly improved access to space and rapid transit throughout the solar system. The laboratory is designed to accommodate researchers from across the United States, including scientists and engineers from NASA, the Department of Defense, the Department of Energy, universities, and industry. The facility, with 66,000 square feet of useable laboratory space, features a high degree of experimental capability. Its flexibility allows it to address a broad range of propulsion technologies and concepts, such as plasma, electromagnetic, thermodynamic, and propellant propulsion. An important area of emphasis is the development and utilization of advanced energy sources, including highly energetic chemical reactions, solar energy, and processes based on fission, fusion, and antimatter. The Propulsion Research Laboratory is vital for developing the advanced propulsion technologies needed to open up the space frontier, and sets the stage of research that could revolutionize space transportation for a broad range of applications.

  17. Transition in the Human Exploration of Space at NASA

    NASA Technical Reports Server (NTRS)

    Koch, Carla A.; Cabana, Robert

    2011-01-01

    NASA is taking the next step in human exploration, beyond low Earth orbit. We have been going to low Earth orbit for the past 50 years and are using this experience to work with commercial companies to perform this function. This will free NASA resources to develop the systems necessary to travel to a Near Earth Asteroid, the Moon, Lagrange Points, and eventually Mars. At KSC, we are positioning ourselves to become a multi-user launch complex and everything we are working on is bringing us closer to achieving this goal. A vibrant multi-use spaceport is to the 21st Century what the airport was to the 20th Century - an invaluable transportation hub that supports government needs while promoting economic development and commercial markets beyond Earth's atmosphere. This past year saw the end of Shuttle, but the announcements of NASA's crew module, Orion, and heavy-lift rocket, the SLS, as well as the establishment of the Commercial Crew Program. We have a busy, but very bright future ahead of us and KSC is looking forward to playing an integral part in the next era of human space exploration. The future is SLS, 21st Century Ground Systems Program, and the Commercial Crew Program; and the future is here.

  18. The future of management: The NASA paradigm

    NASA Technical Reports Server (NTRS)

    Harris, Philip R.

    1992-01-01

    Prototypes of 21st century management, especially for large scale enterprises, may well be found within the aerospace industry. The space era inaugurated a number of projects of such scope and magnitude that another type of management had to be created to ensure successful achievement. The challenges will be not just in terms of technology and its management, but also human and cultural in dimension. Futurists, students of management, and those concerned with technological administration would do well to review the literature of emerging space management for its wider implications. NASA offers a paradigm, or demonstrated model, of future trends in the field of management at large. More research is needed on issues of leadership for Earth based project in space and space based programs with managers there. It is needed to realize that large scale technical enterprises, such as are undertaken in space, require a new form of management. NASA and other responsible agencies are urged to study excellence in space macromanagement, including the necessary multidisciplinary skills. Two recommended targets are the application of general living systems theory and macromanagement concepts for space stations in the 1990s.

  19. Demystifying traditional herbal medicine with modern approach.

    PubMed

    Li, Fu-Shuang; Weng, Jing-Ke

    2017-07-31

    Plants have long been recognized for their therapeutic properties. For centuries, indigenous cultures around the world have used traditional herbal medicine to treat a myriad of maladies. By contrast, the rise of the modern pharmaceutical industry in the past century has been based on exploiting individual active compounds with precise modes of action. This surge has yielded highly effective drugs that are widely used in the clinic, including many plant natural products and analogues derived from these products, but has fallen short of delivering effective cures for complex human diseases with complicated causes, such as cancer, diabetes, autoimmune disorders and degenerative diseases. While the plant kingdom continues to serve as an important source for chemical entities supporting drug discovery, the rich traditions of herbal medicine developed by trial and error on human subjects over thousands of years contain invaluable biomedical information just waiting to be uncovered using modern scientific approaches. Here we provide an evolutionary and historical perspective on why plants are of particular significance as medicines for humans. We highlight several plant natural products that are either in the clinic or currently under active research and clinical development, with particular emphasis on their mechanisms of action. Recent efforts in developing modern multi-herb prescriptions through rigorous molecular-level investigations and standardized clinical trials are also discussed. Emerging technologies, such as genomics and synthetic biology, are enabling new ways for discovering and utilizing the medicinal properties of plants. We are entering an exciting era where the ancient wisdom distilled into the world's traditional herbal medicines can be reinterpreted and exploited through the lens of modern science.

  20. Access NASA Satellite Global Precipitation Data Visualization on YouTube

    NASA Technical Reports Server (NTRS)

    Liu, Z.; Su, J.; Acker, J.; Huffman, G.; Vollmer, B.; Wei, J.; Meyer, D.

    2017-01-01

    Since the satellite era began, NASA has collected a large volume of Earth science observations for research and applications around the world. The collected and archived satellite data at 12 NASA data centers can also be used for STEM education and activities such as disaster events, climate change, etc. However, accessing satellite data can be a daunting task for non-professional users such as teachers and students because of unfamiliarity of terminology, disciplines, data formats, data structures, computing resources, processing software, programming languages, etc. Over the years, many efforts including tools, training classes, and tutorials have been developed to improve satellite data access for users, but barriers still exist for non-professionals. In this presentation, we will present our latest activity that uses a very popular online video sharing Web site, YouTube (https://www.youtube.com/), for accessing visualizations of our global precipitation datasets at the NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC). With YouTube, users can access and visualize a large volume of satellite data without the necessity to learn new software or download data. The dataset in this activity is a one-month animation for the GPM (Global Precipitation Measurement) Integrated Multi-satellite Retrievals for GPM (IMERG). IMERG provides precipitation on a near-global (60 deg. N-S) coverage at half-hourly time interval, providing more details on precipitation processes and development compared to the 3-hourly TRMM (Tropical Rainfall Measuring Mission) Multisatellite Precipitation Analysis (TMPA, 3B42) product. When the retro-processing of IMERG during the TRMM era is finished in 2018, the entire video will contain more than 330,000 files and will last 3.6 hours. Future plans include development of flyover videos for orbital data for an entire satellite mission or project. All videos, including the one-month animation, will be uploaded and

  1. Modern Radiation Therapy for Nodal Non-Hodgkin Lymphoma—Target Definition and Dose Guidelines From the International Lymphoma Radiation Oncology Group

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Illidge, Tim, E-mail: Tim.Illidge@ics.manchester.ac.uk; Specht, Lena; Yahalom, Joachim

    2014-05-01

    Radiation therapy (RT) is the most effective single modality for local control of non-Hodgkin lymphoma (NHL) and is an important component of therapy for many patients. Many of the historic concepts of dose and volume have recently been challenged by the advent of modern imaging and RT planning tools. The International Lymphoma Radiation Oncology Group (ILROG) has developed these guidelines after multinational meetings and analysis of available evidence. The guidelines represent an agreed consensus view of the ILROG steering committee on the use of RT in NHL in the modern era. The roles of reduced volume and reduced doses aremore » addressed, integrating modern imaging with 3-dimensional planning and advanced techniques of RT delivery. In the modern era, in which combined-modality treatment with systemic therapy is appropriate, the previously applied extended-field and involved-field RT techniques that targeted nodal regions have now been replaced by limiting the RT to smaller volumes based solely on detectable nodal involvement at presentation. A new concept, involved-site RT, defines the clinical target volume. For indolent NHL, often treated with RT alone, larger fields should be considered. Newer treatment techniques, including intensity modulated RT, breath holding, image guided RT, and 4-dimensional imaging, should be implemented, and their use is expected to decrease significantly the risk for normal tissue damage while still achieving the primary goal of local tumor control.« less

  2. Commercial use of space - The space business era

    NASA Technical Reports Server (NTRS)

    Griffin, G. D.

    1985-01-01

    Progress and avenues being explored by NASA to hasten the commercialization of space are described. A task force has recommended that the effort begin at once, that bureaucratic barriers to commercial space activities be removed, and that a partnership between government and industry be seriously explored. The government role is to establish links with private industry, invest in high-leverage technologies and space facilities which will be attractive to commercial ventures, and contribute to commercial enterprises where risks are high and significant economic benefits can be foreseen. The government/industry relationship can be legally evinced by MOUs, joint endeavor agreements, technical exchange agreements and industrial guest investigator arrangements. The Space Station is the first step in that it allows Americans to live and work in space. It is expected that international participation in Space Station development and utilization will accelerate the space business era.

  3. NOAA-NASA Coastal Zone Color Scanner reanalysis effort.

    PubMed

    Gregg, Watson W; Conkright, Margarita E; O'Reilly, John E; Patt, Frederick S; Wang, Menghua H; Yoder, James A; Casey, Nancy W

    2002-03-20

    Satellite observations of global ocean chlorophyll span more than two decades. However, incompatibilities between processing algorithms prevent us from quantifying natural variability. We applied a comprehensive reanalysis to the Coastal Zone Color Scanner (CZCS) archive, called the National Oceanic and Atmospheric Administration and National Aeronautics and Space Administration (NOAA-NASA) CZCS reanalysis (NCR) effort. NCR consisted of (1) algorithm improvement (AI), where CZCS processing algorithms were improved with modernized atmospheric correction and bio-optical algorithms and (2) blending where in situ data were incorporated into the CZCS AI to minimize residual errors. Global spatial and seasonal patterns of NCR chlorophyll indicated remarkable correspondence with modern sensors, suggesting compatibility. The NCR permits quantitative analyses of interannual and interdecadal trends in global ocean chlorophyll.

  4. The NASA Dryden AAR Project: A Flight Test Approach to an Aerial Refueling System

    NASA Technical Reports Server (NTRS)

    Hansen, Jennifer L.; Murray, James E.; Campos, Norma V.

    2004-01-01

    The integration of uninhabited aerial vehicles (UAVs) into controlled airspace has generated a new era of autonomous technologies and challenges. Autonomous aerial refueling would enable UAVs to travel further distances and loiter for extended periods over time-critical targets. The NASA Dryden Flight Research Center recently has completed a flight research project directed at developing a dynamic hose and drogue system model to support the development of an automated aerial refueling system. A systematic dynamic model of the hose and drogue system would include the effects of various influences on the system, such as flight condition, hose and drogue type, tanker type and weight, receiver type, and tanker and receiver maneuvering. Using two NASA F/A-18 aircraft and a conventional hose and drogue aerial refueling store from the Navy, NASA has obtained flight research data that document the response of the hose and drogue system to these effects. Preliminary results, salient trends, and important lessons are presented.

  5. Expeditionary Air Base Defense: Historical Cases and Modern Implications

    DTIC Science & Technology

    2017-06-01

    and redesigning is based on peacetime criteria. Seventh Air Force Base Defense Study Group, 1967 The Dien Bien Phu case study offered many...Freedom in 2004-2012. Analysis of these case studies reveals several themes of expeditionary air base defense in the modern era, including: the...IRAQ AND AFGHANISTAN……………………….48 6 ANALYSIS OF CASE STUDIES ………………………………………………62 7 CONCLUSIONS ……………………………………………………………..…67

  6. NASA's First Laser Communication System

    NASA Image and Video Library

    2017-12-08

    A new NASA-developed, laser-based space communication system will enable higher rates of satellite communications similar in capability to high-speed fiber optic networks on Earth. The space terminal for the Lunar Laser Communication Demonstration (LLCD), NASA's first high-data-rate laser communication system, was recently integrated onto the Lunar Atmosphere and Dust Environment Explorer (LADEE) spacecraft. LLCD will demonstrate laser communications from lunar orbit to Earth at six times the rate of the best modern-day advanced radio communication systems. Credit: NASA ----- What is LADEE? The Lunar Atmosphere and Dust Environment Explorer (LADEE) is designed to study the Moon's thin exosphere and the lunar dust environment. An "exosphere" is an atmosphere that is so thin and tenuous that molecules don't collide with each other. Studying the Moon's exosphere will help scientists understand other planetary bodies with exospheres too, like Mercury and some of Jupiter's bigger moons. The orbiter will determine the density, composition and temporal and spatial variability of the Moon's exosphere to help us understand where the species in the exosphere come from and the role of the solar wind, lunar surface and interior, and meteoric infall as sources. The mission will also examine the density and temporal and spatial variability of dust particles that may get lofted into the atmosphere. The mission also will test several new technologies, including a modular spacecraft bus that may reduce the cost of future deep space missions and demonstrate two-way high rate laser communication for the first time from the Moon. LADEE now is ready to launch when the window opens on Sept. 6, 2013. Read more: www.nasa.gov/ladee NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing

  7. New quality assurance program integrating "modern radiotherapy" within the German Hodgkin Study Group.

    PubMed

    Kriz, J; Baues, C; Engenhart-Cabillic, R; Haverkamp, U; Herfarth, K; Lukas, P; Schmidberger, H; Marnitz-Schulze, S; Fuchs, M; Engert, A; Eich, H T

    2017-02-01

    Field design changed substantially from extended-field RT (EF-RT) to involved-field RT (IF-RT) and now to involved-node RT (IN-RT) and involved-site RT (IS-RT) as well as treatment techniques in radiotherapy (RT) of Hodgkin's lymphoma (HL). The purpose of this article is to demonstrate the establishment of a quality assurance program (QAP) including modern RT techniques and field designs within the German Hodgkin Study Group (GHSG). In the era of modern conformal RT, this QAP had to be fundamentally adapted and a new evaluation process has been intensively discussed by the radiotherapeutic expert panel of the GHSG. The expert panel developed guidelines and criteria to analyse "modern" field designs and treatment techniques. This work is based on a dataset of 11 patients treated within the sixth study generation (HD16-17). To develop a QAP of "modern RT", the expert panel defined criteria for analysing current RT procedures. The consensus of a modified QAP in ongoing and future trials is presented. With this schedule, the QAP of the GHSG could serve as a model for other study groups.

  8. Smallpox vaccination: an early start of modern medicine in America.

    PubMed

    Liebowitz, Dan

    2017-01-01

    Smallpox was eradicated by the World Health Organization in 1980. Before its eradication thedisease had a mortality rate upwards of 50% and had a significant impact on society. During theAmerican Revolutionary war, smallpox outbreaks were impeding the American war effort until1777 when George Washington carried out a mass inoculation campaign in the ContinentalArmy that reduced the mortality from smallpox to less than 2%. Inoculation was an early formof vaccination that used live virus from active pustules to induce a milder, but still sometimesdeadly, case of disease. Washington has been credited with helping to ease the burden ofsmallpox on the Army which improved the odds of success against the British. When EdwardJenner's vaccine reached America it was more readily accepted by political and medical leadersdue the success of Washington's inoculation campaign. The Founding Fathers argued thatsmallpox vaccination was the greatest discovery in modern medicine and they were likely correctthat it helped to usher in the modern era of vaccinology.

  9. Tobacco use in silent film: precedents of modern-day substance use portrayals.

    PubMed

    St Romain, Theresa; Hawley, Suzanne R; Ablah, Elizabeth; Kabler, Bethany S; Molgaard, Craig A

    2007-12-01

    Much research has been done into tobacco use portrayals in film since the mid-twentieth century, but the earlier years of Hollywood history have been overlooked. Yet the first decades of the twentieth century saw annual per capita cigarette consumption increase from under 100 in 1900 upto 1,500 in 1930. The current study looks at frequency and context (gender, age range, socioeconomic status, type of portrayal) of tobacco use in 20 top-grossing silent films spanning the silent feature era (1915-1928). The sample averaged 23.31 tobacco uses per hour. Tobacco use was most often associated with positive characterizations, working/middle class status, masculinity, and youth. Previous research has verified the influence of the film industry on tobacco consumption in modern years, and this potential connection should not be ignored for the silent film era. Top-grossing silent films set a precedent for positive media portrayals of substance use that have persisted to the present day.

  10. An investigation of transitional management problems for the NSTS at NASA

    NASA Technical Reports Server (NTRS)

    Hunsucker, John

    1988-01-01

    This quarterly report summarizes the ideas and concepts developed by the University of Houston team with the collaboration and support of the Management Integration Offices of NASA. In addition it is hoped that this report will help to stimulate the healthy problem solving process already present at NASA. This is the second report in the fourth year of the research contract. The main aim of the work is to assist the National Space Transportation System (NSTS) in finding ways and means of moving into a truly operational era in the sense of routine timely production of flights. The reader who seeks an understanding of the concepts presented is encouraged to read the reports of the last three years. The overall strategy of this effort is to: (1) search the literature for applications of transition management and other related issues, (2) conduct investigations into the experiences of the industries with the transition management, and (3) to adapt the information found in (1) and (2) above into a form useful to NASA while at the same time applying industrial engineering and engineering management expertise to problems and issues as they emerge.

  11. Status of barium studies in the present era of oncology: Are they a history?

    PubMed Central

    Mahajan, Abhishek; Desai, Subash; Sable, Nilesh Pandurang; Thakur, Meenakshi Haresh

    2016-01-01

    With the advent of the modern imaging technologies, the present era of oncology is seeing steady decline in requests for barium studies due to the many reasons. It is prudent to mention here, that, barium examinations cannot be made obsolete! Our aim to preserve the age old technique of barium studies not only to keep it going on but also for the betterment and appropriate management of the patient. Our goal is not to “save” barium studies simply to keep this technology alive, per se, but rather to preserve barium radiology for the quality in patient care. PMID:28144086

  12. Status of barium studies in the present era of oncology: Are they a history?

    PubMed

    Mahajan, Abhishek; Desai, Subash; Sable, Nilesh Pandurang; Thakur, Meenakshi Haresh

    2016-01-01

    With the advent of the modern imaging technologies, the present era of oncology is seeing steady decline in requests for barium studies due to the many reasons. It is prudent to mention here, that, barium examinations cannot be made obsolete! Our aim to preserve the age old technique of barium studies not only to keep it going on but also for the betterment and appropriate management of the patient. Our goal is not to "save" barium studies simply to keep this technology alive, per se, but rather to preserve barium radiology for the quality in patient care.

  13. NASA Telescopes Help Identify Most Distant Galaxy Cluster

    NASA Astrophysics Data System (ADS)

    2011-01-01

    WASHINGTON -- Astronomers have uncovered a burgeoning galactic metropolis, the most distant known in the early universe. This ancient collection of galaxies presumably grew into a modern galaxy cluster similar to the massive ones seen today. The developing cluster, named COSMOS-AzTEC3, was discovered and characterized by multi-wavelength telescopes, including NASA's Spitzer, Chandra and Hubble space telescopes, and the ground-based W.M. Keck Observatory and Japan's Subaru Telescope. "This exciting discovery showcases the exceptional science made possible through collaboration among NASA projects and our international partners," said Jon Morse, NASA's Astrophysics Division director at NASA Headquarters in Washington. Scientists refer to this growing lump of galaxies as a proto-cluster. COSMOS-AzTEC3 is the most distant massive proto-cluster known, and also one of the youngest, because it is being seen when the universe itself was young. The cluster is roughly 12.6 billion light-years away from Earth. Our universe is estimated to be 13.7 billion years old. Previously, more mature versions of these clusters had been spotted at 10 billion light-years away. The astronomers also found that this cluster is buzzing with extreme bursts of star formation and one enormous feeding black hole. "We think the starbursts and black holes are the seeds of the cluster," said Peter Capak of NASA's Spitzer Science Center at the California Institute of Technology in Pasadena. "These seeds will eventually grow into a giant, central galaxy that will dominate the cluster -- a trait found in modern-day galaxy clusters." Capak is first author of a paper appearing in the Jan. 13 issue of the journal Nature. Most galaxies in our universe are bound together into clusters that dot the cosmic landscape like urban sprawls, usually centered around one old, monstrous galaxy containing a massive black hole. Astronomers thought that primitive versions of these clusters, still forming and clumping

  14. KSC-2013-1783

    NASA Image and Video Library

    2013-03-05

    CAPE CANAVERAL, Fla. – A telemetry antenna and tracker camera is attached to the roof of the Launch Control Center, or LCC, in Launch Complex 39 at NASA's Kennedy Space Center in Florida. This antenna and camera system is the first of three to be installed on the LCC roof for the Radio Frequency and Telemetry Station RFTS, which will be used to monitor radio frequency communications from a launch vehicle at Launch Pad 39A or B as well as provide radio frequency relay for a launch vehicle in the Vehicle Assembly Building. The RFTS replaces the shuttle-era communications and tracking labs at Kennedy. The modern RFTS checkout station is designed to primarily support NASA's Space Launch System, or SLS, and Orion spacecraft, but can support multi-user radio frequency tests as the space center transitions to support a variety of rockets and spacecraft. For more information on the modernization efforts at Kennedy, visit the Ground Systems Development and Operations, or GSDO, website at http://go.nasa.gov/groundsystems. Photo credit: NASA/Jim Grossmann

  15. Institutional Memory Preservation at NASA Glenn Research Center

    NASA Technical Reports Server (NTRS)

    Coffey, J.; Moreman, Douglas; Dyer, J.; Hemminger, J. A.

    1999-01-01

    In this era of downsizing and deficit reduction, the preservation of institutional memory is a widespread concern for U.S. companies and governmental agencies. The National Aeronautical and Space Administration faces the pending retirement of many of the agency's long-term, senior engineers. NASA has a marvelous long-term history of success, but the agency faces a recurring problem caused by the loss of these engineers' unique knowledge and perspectives on NASA's role in aeronautics and space exploration. The current work describes a knowledge elicitation effort aimed at demonstrating the feasibility of preserving the more personal, heuristic knowledge accumulated over the years by NASA engineers, as contrasted with the "textbook" knowledge of launch vehicles. Work on this project was performed at NASA Glenn Research Center and elsewhere, and focused on launch vehicle systems integration. The initial effort was directed toward an historic view of the Centaur upper stage which is powered by two RL-10 engines. Various experts were consulted, employing a variety of knowledge elicitation techniques, regarding the Centaur and RL-10. Their knowledge is represented in searchable Web-based multimedia presentations. This paper discusses the various approaches to knowledge elicitation and knowledge representation employed, and assesses successes and challenges in trying to perform large-scale knowledge preservation of institutional memory. It is anticipated that strategies for knowledge elicitation and representation that have been developed in this grant will be utilized to elicit knowledge in a variety of domains including the complex heuristics that underly use of simulation software packages such as that being explored in the Expert System Architecture for Rocket Engine Numerical Simulators.

  16. Federal incentives for industrial modernization: Historical review and future opportunities

    NASA Technical Reports Server (NTRS)

    Coleman, Sandra C.; Batson, Robert G.

    1987-01-01

    Concerns over the aging of the U.S. aerospace industrial base led DOD to introduce first its Technology Modernization (Tech Mod) Program, and more recently the Industrial Modernization Incentive Program (IMIP). These incentives include productivity shared savings rewards, contractor investment protection to allow for amortization of plant and equipment, and subcontractor/vendor participation. The purpose here is to review DOD IMIP and to evaluate whether a similar program is feasible for NASA and other non-DOD agencies. The IMIP methodology is of interest to industrial engineers because it provides a structured, disciplined approach to identifying productivity improvement opportunities and documenting their expected benefit. However, it is shown that more research on predicting and validating cost avoidance is needed.

  17. New Developments At The Science Archives Of The NASA Exoplanet Science Institute

    NASA Astrophysics Data System (ADS)

    Berriman, G. Bruce

    2018-06-01

    The NASA Exoplanet Science Institute (NExScI) at Caltech/IPAC is the science center for NASA's Exoplanet Exploration Program and as such, NExScI operates three scientific archives: the NASA Exoplanet Archive (NEA) and Exoplanet Follow-up Observation Program Website (ExoFOP), and the Keck Observatory Archive (KOA).The NASA Exoplanet Archive supports research and mission planning by the exoplanet community by operating a service that provides confirmed and candidate planets, numerous project and contributed data sets and integrated analysis tools. The ExoFOP provides an environment for exoplanet observers to share and exchange data, observing notes, and information regarding the Kepler, K2, and TESS candidates. KOA serves all raw science and calibration observations acquired by all active and decommissioned instruments at the W. M. Keck Observatory, as well as reduced data sets contributed by Keck observers.In the coming years, the NExScI archives will support a series of major endeavours allowing flexible, interactive analysis of the data available at the archives. These endeavours exploit a common infrastructure based upon modern interfaces such as JuypterLab and Python. The first service will enable reduction and analysis of precision radial velocity data from the HIRES Keck instrument. The Exoplanet Archive is developing a JuypterLab environment based on the HIRES PRV interactive environment. Additionally, KOA is supporting an Observatory initiative to develop modern, Python based pipelines, and as part of this work, it has delivered a NIRSPEC reduction pipeline. The ensemble of pipelines will be accessible through the same environments.

  18. Nasa astronauts, prosthetics and the manned space program.

    PubMed

    Frenger, Paul

    2014-01-01

    The author has collaborated with NASA astronauts, scientists and engineers since 2006. Manned deep space missions, beyond the Moon’s orbit, are being planned in this post-Shuttle era. The spacecraft required for longer flights will have relatively restricted crew interior volume. To decrease the negative impact of these tight quarters, the author has proposed recruiting smaller astronauts (abbreviated SAs), persons about one-half the height of current near-Earth crewmembers. This includes achondroplastic dwarfs, lower extremity amputees and persons with certain height-reducing birth defects such as phocomelia. To overcome issues of physical competence, strength and mobility of SAs, the author describes using advanced cybernetic prostheses for those with limb amputations or deformities, and motorized exoskeletons for the others. Muscle and bone-sparing space exercise programs for SAs should be simpler. For example, a motorized exoskeleton used for routine duties in space would also provide both resistance workouts and passive range of motion conditioning for the astronauts, even while resting. Complex personalized artificial intelligence functions may be added. These initial suggestions previously presented to NASA offer a starting point for deep space manned missions to the asteroid belt, Mars and beyond.

  19. NASA's Next Generation Space Geodesy Network

    NASA Technical Reports Server (NTRS)

    Desai, S. D.; Gross, R. S.; Hilliard, L.; Lemoine, F. G.; Long, J. L.; Ma, C.; McGarry, J. F.; Merkowitz, S. M.; Murphy, D.; Noll, C. E.; hide

    2012-01-01

    NASA's Space Geodesy Project (SGP) is developing a prototype core site for a next generation Space Geodetic Network (SGN). Each of the sites in this planned network co-locate current state-of-the-art stations from all four space geodetic observing systems, GNSS, SLR, VLBI, and DORIS, with the goal of achieving modern requirements for the International Terrestrial Reference Frame (ITRF). In particular, the driving ITRF requirements for this network are 1.0 mm in accuracy and 0.1 mm/yr in stability, a factor of 10-20 beyond current capabilities. Development of the prototype core site, located at NASA's Geophysical and Astronomical Observatory at the Goddard Space Flight Center, started in 2011 and will be completed by the end of 2013. In January 2012, two operational GNSS stations, GODS and GOON, were established at the prototype site within 100 m of each other. Both stations are being proposed for inclusion into the IGS network. In addition, work is underway for the inclusion of next generation SLR and VLBI stations along with a modern DORIS station. An automated survey system is being developed to measure inter-technique vectorties, and network design studies are being performed to define the appropriate number and distribution of these next generation space geodetic core sites that are required to achieve the driving ITRF requirements. We present the status of this prototype next generation space geodetic core site, results from the analysis of data from the established geodetic stations, and results from the ongoing network design studies.

  20. Astronaut Medical Selection and Flight Medicine Care During the Shuttle ERA 1981 to 2011

    NASA Technical Reports Server (NTRS)

    Johnston, S.; Jennings, R.; Stepaniak, P.; Schmid, J.; Rouse, B.; Gray, G.; Tarver, B.

    2011-01-01

    The NASA Shuttle Program began with congressional budget approval in January 5, 1972 and the launch of STS-1 on April 12, 1981 and recently concluded with the landing of STS-135 on July 21, 2011. The evolution of the medical standards and care of the Shuttle Era Astronauts began in 1959 with the first Astronaut selection. The first set of NASA minimal medical standards were documented in 1977 and based on Air Force, Navy, Department of Defense, and the Federal Aviation Administration standards. Many milestones were achieved over the 30 years from 1977 to 2007 and the subsequent 13 Astronaut selections and 4 major expert panel reviews performed by the NASA Flight Medicine Clinic, Aerospace Medicine Board, and Medical Policy Board. These milestones of aerospace medicine standards, evaluations, and clinical care encompassed the disciplines of preventive, occupational, and primary care medicine and will be presented. The screening and retention standards, testing, and specialist evaluations evolved through periodic expert reviews, evidence based medicine, and Astronaut medical care experience. The last decade of the Shuttle Program saw the development of the International Space Station (ISS) with further Space medicine collaboration and knowledge gained from our International Partners (IP) from Russia, Canada, Japan, and the European Space Agencies. The Shuttle Program contribution to the development and implementation of NASA and IP standards and waiver guide documents, longitudinal data collection, and occupational surveillance models will be presented along with lessons learned and recommendations for future vehicles and missions.

  1. NASA's Next Generation Space Geodesy Program

    NASA Technical Reports Server (NTRS)

    Pearlman, M. R.; Frey, H. V.; Gross, R. S.; Lemoine, F. G.; Long, J. L.; Ma, C.; McGarry J. F.; Merkowitz, S. M.; Noll, C. E.; Pavilis, E. C.; hide

    2012-01-01

    Requirements for the ITRF have increased dramatically since the 1980s. The most stringent requirement comes from critical sea level monitoring programs: a global accuracy of 1.0 mm, and 0.1mm/yr stability, a factor of 10 to 20 beyond current capability. Other requirements for the ITRF coming from ice mass change, ground motion, and mass transport studies are similar. Current and future satellite missions will have ever-increasing measurement capability and will lead to increasingly sophisticated models of these and other changes in the Earth system. Ground space geodesy networks with enhanced measurement capability will be essential to meeting the ITRF requirements and properly interpreting the satellite data. These networks must be globally distributed and built for longevity, to provide the robust data necessary to generate improved models for proper interpretation of the observed geophysical signals. NASA has embarked on a Space Geodesy Program with a long-range goal to build, deploy and operate a next generation NASA Space Geodetic Network (SGN). The plan is to build integrated, multi-technique next-generation space geodetic observing systems as the core contribution to a global network designed to produce the higher quality data required to maintain the Terrestrial Reference Frame and provide information essential for fully realizing the measurement potential of the current and coming generation of Earth Observing spacecraft. Phase 1 of this project has been funded to (1) Establish and demonstrate a next-generation prototype integrated Space Geodetic Station at Goddard s Geophysical and Astronomical Observatory (GGAO), including next-generation SLR and VLBI systems along with modern GNSS and DORIS; (2) Complete ongoing Network Design Studies that describe the appropriate number and distribution of next-generation Space Geodetic Stations for an improved global network; (3) Upgrade analysis capability to handle the next-generation data; (4) Implement a modern

  2. NASA's Next Generation Space Geodesy Program

    NASA Technical Reports Server (NTRS)

    Merkowitz, S. M.; Desai, S. D.; Gross, R. S.; Hillard, L. M.; Lemoine, F. G.; Long, J. L.; Ma, C.; McGarry, J. F.; Murphy, D.; Noll, C. E.; hide

    2012-01-01

    Requirements for the ITRF have increased dramatically since the 1980s. The most stringent requirement comes from critical sea level monitoring programs: a global accuracy of 1.0 mm, and 0.1mm/yr stability, a factor of 10 to 20 beyond current capability. Other requirements for the ITRF coming from ice mass change, ground motion, and mass transport studies are similar. Current and future satellite missions will have ever-increasing measurement capability and will lead to increasingly sophisticated models of these and other changes in the Earth system. Ground space geodesy networks with enhanced measurement capability will be essential to meeting the ITRF requirements and properly interpreting the satellite data. These networks must be globally distributed and built for longevity, to provide the robust data necessary to generate improved models for proper interpretation of the observed geophysical signals. NASA has embarked on a Space Geodesy Program with a long-range goal to build, deploy and operate a next generation NASA Space Geodetic Network (SGN). The plan is to build integrated, multi-technique next-generation space geodetic observing systems as the core contribution to a global network designed to produce the higher quality data required to maintain the Terrestrial Reference Frame and provide information essential for fully realizing the measurement potential of the current and coming generation of Earth Observing spacecraft. Phase 1 of this project has been funded to (1) Establish and demonstrate a next-generation prototype integrated Space Geodetic Station at Goddard's Geophysical and Astronomical Observatory (GGAO), including next-generation SLR and VLBI systems along with modern GNSS and DORIS; (2) Complete ongoing Network Design Studies that describe the appropriate number and distribution of next-generation Space Geodetic Stations for an improved global network; (3) Upgrade analysis capability to handle the next-generation data; (4) Implement a modern

  3. NASA's Productivity Improvement and Quality Enhancement Initiatives

    NASA Technical Reports Server (NTRS)

    1984-01-01

    The National Aeronautics and Space Administration celebrated its 25th Anniversary in 1983 at the Air and Space Museum in Washington, DC, with President Reagan in attendance. We look back on the accomplishments of these twenty-five years with pride in our missions and our people. NASA captured the world's imagination during the days of the Apollo mission. So much so, that we now talk about the Apollo era. In the l970s, we moved into the Space Transportation business and in the 199Os, we look forward to having a manned Space Station. Each succeeding mission has presented its own challenge in terms of technology and resources. This is especially true today, when we are being asked to do more with less. To ensure that NASA continues to be a productive and quality conscious agency, one of our highest Agency goals is leadership in the development and application of practices which contribute to high productivity and quality. greatest competitive strength, and this country has a solid scientific and engineering foundation. Traditionally we have spent more money on research and development than Japan and Europe combined, and we are the source of most of this century significant innovations. We should build on this solid base and use it more effectively.

  4. Does using different modern climate datasets impact pollen-based paleoclimate reconstructions in North America during the past 2,000 years

    NASA Astrophysics Data System (ADS)

    Ladd, Matthew; Viau, Andre

    2013-04-01

    Paleoclimate reconstructions rely on the accuracy of modern climate datasets for calibration of fossil records under the assumption of climate normality through time, which means that the modern climate operates in a similar manner as over the past 2,000 years. In this study, we show how using different modern climate datasets have an impact on a pollen-based reconstruction of mean temperature of the warmest month (MTWA) during the past 2,000 years for North America. The modern climate datasets used to explore this research question include the: Whitmore et al., (2005) modern climate dataset; North American Regional Reanalysis (NARR); National Center For Environmental Prediction (NCEP); European Center for Medium Range Weather Forecasting (ECMWF) ERA-40 reanalysis; WorldClim, Global Historical Climate Network (GHCN) and New et al., which is derived from the CRU dataset. Results show that some caution is advised in using the reanalysis data on large-scale reconstructions. Station data appears to dampen out the variability of the reconstruction produced using station based datasets. The reanalysis or model-based datasets are not recommended for paleoclimate large-scale North American reconstructions as they appear to lack some of the dynamics observed in station datasets (CRU) which resulted in warm-biased reconstructions as compared to the station-based reconstructions. The Whitmore et al. (2005) modern climate dataset appears to be a compromise between CRU-based datasets and model-based datasets except for the ERA-40. In addition, an ultra-high resolution gridded climate dataset such as WorldClim may only be useful if the pollen calibration sites in North America have at least the same spatial precision. We reconstruct the MTWA to within +/-0.01°C by using an average of all curves derived from the different modern climate datasets, demonstrating the robustness of the procedure used. It may be that the use of an average of different modern datasets may reduce the

  5. NASA's future Earth observation plans

    NASA Astrophysics Data System (ADS)

    Neeck, Steven P.; Paules, Granville E.; McCuistion Ramesh, J. D.

    2004-11-01

    NASA's Science Mission Directorate, working with its domestic and international partners, provides accurate, objective scientific data and analysis to advance our understanding of Earth system processes. Learning more about these processes will enable improved prediction capability for climate, weather, and natural hazards. Earth interactions occur on a continuum of spatial and temporal scales ranging from short-term weather to long-term climate, and from local and regional to global. Quantitatively describing these changes means precisely measuring from space scores of biological and geophysical parameters globally. New missions that SMD will launch in the coming decade will complement the first series of the Earth Observing System. These next generation systematic measurement missions are being planned to extend or enhance the record of science-quality data necessary for understanding and predicting global change. These missions include the NPOESS Preparatory Project, Ocean Surface Topography Mission, Global Precipitation Measurement, Landsat Data Continuity Mission, and an aerosol polarimetry mission called Glory. New small explorer missions will make first of a kind Earth observations. The Orbiting Carbon Observatory will measure sources and sinks of carbon to help the Nation and the world formulate effective strategies to constrain the amount of this greenhouse gas in the atmosphere. Aquarius will measure ocean surface salinity which is key to ocean circulation in the North Atlantic that produces the current era's mild climate in northern Europe. HYDROS will measure soil moisture globally. Soil moisture is critical to agriculture and to managing fresh water resources. NASA continues to design, develop and launch the Nation's civilian operational environmental satellites, in both polar and geostationary orbits, by agreement with the National Oceanic and Atmospheric Administration (NOAA). NASA plans to develop an advanced atmospheric sounder, GIFTS, for

  6. The More Things Change, the More They Stay the Same: Gleaning Valuable Insights for Modern Educational Leadership from the Life of Harriet Tubman

    ERIC Educational Resources Information Center

    Schenck, Andrew D.

    2015-01-01

    Late in the 19th century, American communities were in a state of flux. As northern abolitionists fought against slavery, relationships among diverse members of society rapidly changed, forcing historical figures to adopt new leadership strategies. Like communities of the pre- and post-Civil War era, modern educational contexts reveal growing…

  7. Aerodynamic Characterization of a Modern Launch Vehicle

    NASA Technical Reports Server (NTRS)

    Hall, Robert M.; Holland, Scott D.; Blevins, John A.

    2011-01-01

    A modern launch vehicle is by necessity an extremely integrated design. The accurate characterization of its aerodynamic characteristics is essential to determine design loads, to design flight control laws, and to establish performance. The NASA Ares Aerodynamics Panel has been responsible for technical planning, execution, and vetting of the aerodynamic characterization of the Ares I vehicle. An aerodynamics team supporting the Panel consists of wind tunnel engineers, computational engineers, database engineers, and other analysts that address topics such as uncertainty quantification. The team resides at three NASA centers: Langley Research Center, Marshall Space Flight Center, and Ames Research Center. The Panel has developed strategies to synergistically combine both the wind tunnel efforts and the computational efforts with the goal of validating the computations. Selected examples highlight key flow physics and, where possible, the fidelity of the comparisons between wind tunnel results and the computations. Lessons learned summarize what has been gleaned during the project and can be useful for other vehicle development projects.

  8. 77 FR 12080 - Era Systems, LLC, Formerly Era Systems Corporation, a Subsidiary of Systems Research and...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-28

    ... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-81,047] Era Systems, LLC, Formerly Era Systems Corporation, a Subsidiary of Systems Research and Applications Corporation, Syracuse, NY; Notice of Affirmative Determination Regarding Application for Reconsideration By application dated February 2, 2012, a worker requested...

  9. Patient Privacy in the Era of Big Data.

    PubMed

    Kayaalp, Mehmet

    2018-01-20

    Privacy was defined as a fundamental human right in the Universal Declaration of Human Rights at the 1948 United Nations General Assembly. However, there is still no consensus on what constitutes privacy. In this review, we look at the evolution of privacy as a concept from the era of Hippocrates to the era of social media and big data. To appreciate the modern measures of patient privacy protection and correctly interpret the current regulatory framework in the United States, we need to analyze and understand the concepts of individually identifiable information, individually identifiable health information, protected health information, and de-identification. The Privacy Rule of the Health Insurance Portability and Accountability Act defines the regulatory framework and casts a balance between protective measures and access to health information for secondary (scientific) use. The rule defines the conditions when health information is protected by law and how protected health information can be de-identified for secondary use. With the advents of artificial intelligence and computational linguistics, computational text de-identification algorithms produce de-identified results nearly as well as those produced by human experts, but much faster, more consistently and basically for free. Modern clinical text de-identification systems now pave the road to big data and enable scientists to access de-identified clinical information while firmly protecting patient privacy. However, clinical text de-identification is not a perfect process. In order to maximize the protection of patient privacy and to free clinical and scientific information from the confines of electronic healthcare systems, all stakeholders, including patients, health institutions and institutional review boards, scientists and the scientific communities, as well as regulatory and law enforcement agencies must collaborate closely. On the one hand, public health laws and privacy regulations define rules

  10. Patient Privacy in the Era of Big Data

    PubMed Central

    Kayaalp, Mehmet

    2018-01-01

    Privacy was defined as a fundamental human right in the Universal Declaration of Human Rights at the 1948 United Nations General Assembly. However, there is still no consensus on what constitutes privacy. In this review, we look at the evolution of privacy as a concept from the era of Hippocrates to the era of social media and big data. To appreciate the modern measures of patient privacy protection and correctly interpret the current regulatory framework in the United States, we need to analyze and understand the concepts of individually identifiable information, individually identifiable health information, protected health information, and de-identification. The Privacy Rule of the Health Insurance Portability and Accountability Act defines the regulatory framework and casts a balance between protective measures and access to health information for secondary (scientific) use. The rule defines the conditions when health information is protected by law and how protected health information can be de-identified for secondary use. With the advents of artificial intelligence and computational linguistics, computational text de-identification algorithms produce de-identified results nearly as well as those produced by human experts, but much faster, more consistently and basically for free. Modern clinical text de-identification systems now pave the road to big data and enable scientists to access de-identified clinical information while firmly protecting patient privacy. However, clinical text de-identification is not a perfect process. In order to maximize the protection of patient privacy and to free clinical and scientific information from the confines of electronic healthcare systems, all stakeholders, including patients, health institutions and institutional review boards, scientists and the scientific communities, as well as regulatory and law enforcement agencies must collaborate closely. On the one hand, public health laws and privacy regulations define rules

  11. Modernization and new technologies: Coping with the information explosion

    NASA Technical Reports Server (NTRS)

    Blados, Walter R.; Cotter, Gladys A.

    1993-01-01

    Information has become a valuable and strategic resource in all societies and economies. Scientific and technical information is especially important in developing and maintaining a strong national science and technology base. The expanding use of information technology, the growth of interdisciplinary research, and an increase in international collaboration are changing characteristics of information. This modernization effort applies new technology to current processes to provide near-term benefits to the user. At the same time, we are developing a long-term modernization strategy designed to transition the program to a multimedia, global 'library without walls'. Notwithstanding this modernization program, it is recogized that no one information center can hope to collect all the relevant data. We see information and information systems changing and becoming more international in scope. We are finding that many nations are expending resources on national systems which duplicate each other. At the same time that this duplication exists, many useful sources of aerospace information are not being collected to cover expanded sources of information. This paper reviews the NASA modernization program and raises for consideration new possibilities for unification of the various aerospace database efforts toward a cooperative international aerospace database initiative, one that can optimize the cost/benefit equation for all participants.

  12. Enhancing Access to and Use of NASA Earth Sciences Data via CUAHSI-HIS (Hydrologic Information System) and Other Hydrologic Community Tools

    NASA Astrophysics Data System (ADS)

    Rui, H.; Strub, R.; Teng, W. L.; Vollmer, B.; Mocko, D. M.; Maidment, D. R.; Whiteaker, T. L.

    2013-12-01

    The way NASA earth sciences data are typically archived (by time steps, one step per file, often containing multiple variables) is not optimal for their access by the hydrologic community, particularly if the data volume and/or number of data files are large. To enhance the access to and use of these NASA data, the NASA Goddard Earth Sciences Data and Information Services Center (GES DISC) adopted two approaches, in a project supported by the NASA ACCESS Program. The first is to optimally reorganize two large hydrological data sets for more efficient access, as time series, and to integrate the time series data (aka 'data rods') into hydrologic community tools, such as CUAHSI-HIS, EPA-BASINS, and Esri-ArcGIS. This effort has thus far resulted in the reorganization and archive (as data rods) of the following variables from the North American and Global Land Data Assimilation Systems (NLDAS and GLDAS, respectively): precipitation, soil moisture, evapotranspiration, runoff, near-surface specific humidity, potential evaporation, soil temperature, near surface air temperature, and near-surface wind. The second approach is to leverage the NASA Simple Subset Wizard (SSW), which was developed to unite data search and subsetters at various NASA EOSDIS data centers into a single, simple, seamless process. Data accessed via SSW are converted to time series before being made available via Web service. Leveraging SSW makes all data accessible via SSW potentially available to HIS users, which increases the number of data sets available as time series beyond those available as data rods. Thus far, a set of selected variables from the NASA Modern Era-Retrospective Analysis for Research and Applications Land Surface (MERRA-Land) data set has been integrated into CUAHSI-HIS, including evaporation, land surface temperature, runoff, soil moisture, soil temperature, precipitation, and transpiration. All data integration into these tools has been conducted in collaboration with their

  13. Preparing for the High Frontier: The Role and Training of NASA Astronauts in the Post- Space Shuttle Era

    NASA Technical Reports Server (NTRS)

    2011-01-01

    In May 2010, the National Research Council (NRC) was asked by NASA to address several questions related to the Astronaut Corps. The NRC s Committee on Human Spaceflight Crew Operations was tasked to answer several questions: 1. How should the role and size of the activities managed by the Johnson Space Center Flight Crew Operations Directorate change after space shuttle retirement and completion of the assembly of the International Space Station (ISS)? 2. What are the requirements for crew-related ground-based facilities after the Space Shuttle program ends? 3. Is the fleet of aircraft used for training the Astronaut Corps a cost-effective means of preparing astronauts to meet the requirements of NASA s human spaceflight program? Are there more cost-effective means of meeting these training requirements? Although the future of NASA s human spaceflight program has garnered considerable discussion in recent years and there is considerable uncertainty about what the program will involve in the coming years, the committee was not tasked to address whether human spaceflight should continue or what form it should take. The committee s task restricted it to studying activities managed by the Flight Crew Operations Directorate or those closely related to its activities, such as crew-related ground-based facilities and the training aircraft.

  14. Chemical Pollution from Combustion of Modern Spacecraft Materials

    NASA Technical Reports Server (NTRS)

    Mudgett, Paul D.

    2013-01-01

    Fire is one of the most critical contingencies in spacecraft and any closed environment including submarines. Currently, NASA uses particle based technology to detect fires and hand-held combustion product monitors to track the clean-up and restoration of habitable cabin environment after the fire is extinguished. In the future, chemical detection could augment particle detection to eliminate frequent nuisance false alarms triggered by dust. In the interest of understanding combustion from both particulate and chemical generation, NASA Centers have been collaborating on combustion studies at White Sands Test Facility using modern spacecraft materials as fuels, and both old and new technology to measure the chemical and particulate products of combustion. The tests attempted to study smoldering pyrolysis at relatively low temperatures without ignition to flaming conditions. This paper will summarize the results of two 1-week long tests undertaken in 2012, focusing on the chemical products of combustion. The results confirm the key chemical products are carbon monoxide (CO), hydrogen cyanide (HCN), hydrogen fluoride (HF) and hydrogen chloride (HCl), whose concentrations depend on the particular material and test conditions. For example, modern aerospace wire insulation produces significant concentration of HF, which persists in the test chamber longer than anticipated. These compounds are the analytical targets identified for the development of new tunable diode laser based hand-held monitors, to replace the aging electrochemical sensor based devices currently in use on the International Space Station.

  15. Modernity and postmodernity in the genesis of transhumanism-posthumanism.

    PubMed

    Pastor, Luis Miguel; García Cuadrado, José Ángel

    2014-01-01

    There are various authors who, within the realm of bioethics, propose as a model of the human being, a man who is enhanced, transhuman or even posthuman. The philosophical roots of these bioethical thinkers have not been sufficiently analysed. In this article our aim is to demonstrate the connection of this movement with the evolution of philosophy over the past several decades. Therefore, and keeping in mind that the transhumanist-posthumanist proposals appeared in the last decades of the 20th century, a time when important philosophical change was afoot, with a movement from the modern age to the postmodern, we begin our article by identifying the philosophical characteristics of both periods, as well as the relationship that exists between them. We will analyse synthetically the conception of the human being, of ethics and of empirical science in both periods, coming to the conclusion that the postmodern era is the result of the radicalization of ideas that were already latent in modernity. Afterwards, and following a brief summary of the postulates of transhumanism-posthumanism, we study the links that this current of thought has with modern and postmodern perspectives regarding the human person, ethics and technoscientific activity. We conclude that even though transhumanist-posthumanist thought has roots in modernity, its objectives and their theoretical bases reveal a strong dependence on postmodern thought. And further, since this latter current of thought is, at base, antihumanist it is logical that transhumanism-posthumanism, influenced by postmodernity, would reveal a strong tendency not merely to negate what the human being is, but even to forget what it is out of a desire to construct something different from the human in the future.

  16. Regional Differences in Stratospheric Intrusions over the USA Investigated using the NASA MERRA-2 Reanalysis

    NASA Astrophysics Data System (ADS)

    Knowland, K. E.; Ott, L.; Hodges, K.; Wargan, K.; Duncan, B. N.

    2016-12-01

    Stratospheric intrusions (SI) - the introduction of ozone-rich stratospheric air into the troposphere - have been linked with surface ozone air quality exceedences, especially at the high elevations in the western USA in springtime. However, the impact of SIs in the remaining seasons and over the rest of the USA is less clear. This study investigates the atmospheric dynamics that generate SIs over the western USA and the different mechanisms through which SIs may influence atmospheric chemistry and surface air quality over the eastern USA. An analysis of the spatiotemporal variability of SIs over the continental US is performed using NASA's Modern-Era Retrospective Analysis for Research and Applications Version-2 (MERRA-2) reanalysis dataset and other Goddard Earth Observing System Model, Version 5 (GEOS-5) model products. Both upper-level and lower-level dynamical features are examined on seasonal timescales using the tracking algorithm of Hodges (1995, 1999). We show how upper-level relative vorticity maxima - representing troughs and cut-off lows - can be tracked and related to the lower-level storm tracks. The influence of both sets of tracks on the assimilated MERRA-2 ozone and meteorological parameters throughout the troposphere and lower stratosphere is quantified. By focusing on the major modes of variability that influence the weather patterns in the USA, namely the Pacific North American (PNA) pattern, Arctic Oscillation (AO) and the North Atlantic Oscillation (NAO), predicative patterns in the meteorological fields that are associated with SIs are identified for their regional effects.

  17. The Modern Design of Experiments: A Technical and Marketing Framework

    NASA Technical Reports Server (NTRS)

    DeLoach, R.

    2000-01-01

    A new wind tunnel testing process under development at NASA Langley Research Center, called Modern Design of Experiments (MDOE), differs from conventional wind tunnel testing techniques on a number of levels. Chief among these is that MDOE focuses on the generation of adequate prediction models rather than high-volume data collection. Some cultural issues attached to this and other distinctions between MDOE and conventional wind tunnel testing are addressed in this paper.

  18. Snow Radiance Data Assimilation over High Mountain Asia Using the NASA Land Information System and a Well-Trained Support Vector Machine

    NASA Astrophysics Data System (ADS)

    Kwon, Y.; Forman, B. A.; Yoon, Y.; Kumar, S.

    2017-12-01

    High Mountain Asia (HMA) has been progressively losing ice and snow in recent decades, which could negatively impact regional water supply and native ecosystems. One goal of this study is to characterize the spatiotemporal variability of snow (and ice) across the HMA region. In addition, modeled snow water equivalent (SWE) estimates will be enhanced through the assimilation of passive microwave brightness temperatures (TB) collected by the Advanced Microwave Scanning Radiometer for Earth Observing System (AMSR-E) as part of a radiance assimilation system. The radiance assimilation framework includes the NASA Land Information System (LIS) in conjunction with a well-trained support vector machine (SVM) that acts as the observation operator. The Noah Land Surface Model with multi-parameterization options (Noah-MP) is used as the prior model for simulating snow dynamics. Noah-MP is forced by meteorological fields from the NASA Modern-Era Retrospective analysis for Research and Applications, version 2 (MERRA-2) atmospheric reanalysis for the periods 01 Sep. 2002 to 01 Sep. 2011. The radiance assimilation system requires two separate phases: 1) training and 2) assimilation. During the training phase, a nonlinear SVM is generated for three different AMSR-E frequencies - 10.65, 18.7, and 36.5 GHz - at both vertical and horizontal polarization. The trained SVM is then used to predict TB during the assimilation phase. An ensemble Kalman filter will be used to condition the model on AMSR-E brightness temperatures not used during SVM training. The performance of the Noah-MP (with and without radiance assimilation) will be assessed via comparison to in-situ measurements, remotely-sensing geophysical retrievals, and other reanalysis products.

  19. Lagrangian large eddy simulations of boundary layer clouds on ERA-Interim and ERA5 trajectories

    NASA Astrophysics Data System (ADS)

    Kazil, J.; Feingold, G.; Yamaguchi, T.

    2017-12-01

    This exploratory study examines Lagrangian large eddy simulations of boundary layer clouds along wind trajectories from the ERA-Interim and ERA5 reanalyses. The study is motivated by the need for statistically representative sets of high resolution simulations of cloud field evolution in realistic meteorological conditions. The study will serve as a foundation for the investigation of biomass burning effects on the transition from stratocumulus to shallow cumulus clouds in the South-East Atlantic. Trajectories that pass through a location with radiosonde data (St. Helena) and which exhibit a well-defined cloud structure and evolution were identified in satellite imagery, and sea surface temperature and atmospheric vertical profiles along the trajectories were extracted from the reanalysis data sets. The System for Atmospheric Modeling (SAM) simulated boundary layer turbulence and cloud properties along the trajectories. Mean temperature and moisture (in the free troposphere) and mean wind speed (at all levels) were nudged towards the reanalysis data. Atmospheric and cloud properties in the large eddy simulations were compared with those from the reanalysis products, and evaluated with satellite imagery and radiosonde data. Simulations using ERA-Interim data and the higher resolution ERA5 data are contrasted.

  20. MERRA-2: File Specification

    NASA Technical Reports Server (NTRS)

    Bosilovich, M. G.; Lucchesi, R.; Suarez, M.

    2015-01-01

    The second Modern-Era Retrospective analysis for Research and Applications (MERRA-2) is a NASA atmospheric reanalysis that begins in 1980. It replaces the original MERRA reanalysis (Rienecker et al., 2011) using an upgraded version of the Goddard Earth Observing System Model, Version 5 (GEOS-5) data assimilation system. The file collections for MERRA-2 are described in detail in this document, including some important changes from those of the MERRA dataset (Lucchesi, 2012).

  1. Age of air and heating rates: comparison of ERA-40 with ERA-Interim

    NASA Astrophysics Data System (ADS)

    Legras, B.; Fueglistaler, S.

    2009-04-01

    The age of air in the stratosphere is often used as a test for the good representation of the Brewer-Dobson circulation by atmospheric models. This is a critical requirement to modelize the distribution of long-lived species in chemical models. It is often advocated that using heating rates for vertical transport in the stratosphere performs better that standard analysed velocities from weather centers. This work is based on an extensive comparison of the age of air using 5 years of heating rates from the ERA-40 reanalysis and from the new ERA-interim reanalysis built with 4D-Var assimilation. The ERA-40 exhibits both too young ages with analyzed velocities and too old ages with heating rates. The reason for too young ages is spurious transport associated with too noisy wind, as a result of 3D-Var assimilation. Heating rates provide a much less noisy meridional circulation and preserve transport barriers and polar vortex confinement. However, excessive cooling near 30 hPa in the tropics blocks the ascending motion within the tropical pipe over extended periods of time inducing very old ages. This effect is usually corrected by an empirical correction which can exceed in some regions the calculated heating rate in magnitude, with opposite sign. We relate this correction to the assimilation temperature increment that is required to compensate the bias of the model, notably the excessive negative heat transport due to the noisy vertical velocities and the lack of mass conservation in the isentropic frame. The new ERA-interim exhibits much reduced noise in the vertical velocity and is ten times less diffusive than the ERA-40 in the tropics. Age of air is then found to be slightly older than given by the observations. The biases in the heating rate have also been considerably reduced with respect to ERA-40 and the assimilation increment is now only a fraction of the heating rate. The age of air is in fairly good aggreement with the observations at 20 km and higher

  2. Early-time cosmology with stiff era from modified gravity

    NASA Astrophysics Data System (ADS)

    Odintsov, S. D.; Oikonomou, V. K.

    2017-11-01

    In this work, we shall incorporate a stiff era in the Universe's evolution in the context of F (R ) gravity. After deriving the vacuum F (R ) gravity, which may realize a stiff evolution, we combine the stiff F (R ) gravity with an R2 model, and we construct a qualitative model for the inflationary and stiff era, with the latter commencing after the end of the inflationary era. We assume that the baryogenesis occurs during the stiff era, and we calculate the baryon to entropy ratio, which effectively constraints the functional form of the stiff F (R ) gravity. Further constraints on the stiff F (R ) gravity may come from the primordial gravitational waves, and particularly their scalar mode, which is characteristic of the F (R ) gravity theory. The stiff era presence does not contradict the standard cosmology era, namely, inflation, and the radiation-matter domination eras. Furthermore, we investigate which F (R ) gravity may realize a dust and stiff matter dominated Einstein-Hilbert evolution.

  3. A New Era of Symmetries in the Hadronic Interaction

    NASA Astrophysics Data System (ADS)

    Crawford, Christopher

    2016-09-01

    The search for a weak component of the nuclear force began in 1957, shortly after the proposal of parity violation. While it has been observed in compound nuclei with large nuclear enhancements, a systematic characterization of the hadronic weak interaction is still forthcoming almost sixty years later. New experimental facilities and technology have rejuvenated efforts to map out this ``complexity frontier'' within the Standard Model, and we will soon have precision data from multiple few-body experiments. In parallel, modern effective field theories have provided a systematic model independent description of the hadronic interaction with estimates of higher-order effects. The characterization of discrete symmetries in hadronic systems has recently become important for the design and analysis of other precision symmetries measurements, for example, electron PV scattering and time-reversal violation experiments. These new developments in experiment, theory, and application have ushered in a new era in hadronic parity violation. We acknowledge support from DOE-NP under Contract DE-SC0008107.

  4. Recommended Capacities for Educational Leadership: Pre-Reform Era Scholars versus Reform-Era Scholars versus National Standards

    ERIC Educational Resources Information Center

    Gordon, Stephen P.; Taylor-Backor, Karen; Croteau, Susan

    2017-01-01

    We reviewed the scholarship on capacities for educational leadership for the past decade of the pre-reform era (1976-1985), as well as a recent decade of the reform era (2005-2015), and compared scholarship from both decades with the current Professional Standards for Educational Leaders. We found that scholars in the past decade of the pre-reform…

  5. KSC-2013-1782

    NASA Image and Video Library

    2013-03-05

    CAPE CANAVERAL, Fla. – With the help of a crane, a worker helps guide a parabolic telemetry antenna and tracker camera to the roof of the Launch Control Center, or LCC, in Launch Complex 39 at NASA's Kennedy Space Center in Florida. This antenna and camera system is the first of three that will be installed on the LCC roof for the Radio Frequency and Telemetry Station RFTS, which will be used to monitor radio frequency communications from a launch vehicle at Launch Pad 39A or B as well as provide radio frequency relay for a launch vehicle in the Vehicle Assembly Building. The RFTS replaces the shuttle-era communications and tracking labs at Kennedy. The modern RFTS checkout station is designed to primarily support NASA's Space Launch System, or SLS, and Orion spacecraft, but can support multi-user radio frequency tests as the space center transitions to support a variety of rockets and spacecraft. For more information on the modernization efforts at Kennedy, visit the Ground Systems Development and Operations, or GSDO, website at http://go.nasa.gov/groundsystems. Photo credit: NASA/Jim Grossmann

  6. NASA Update

    NASA Image and Video Library

    2010-04-08

    "NASA Update" program with NASA Administrator Charles Bolden, NASA Deputy Administrator Lori Garver and NASA Acting Asistant Administrator for Public Affairs Bob Jacobs as moderator, NASA Headquarters, Thursday, April 8, 2010 in Washington. Photo Credit: (NASA/Bill Ingalls)

  7. "Physics Stories": How the Early Technologies of High Voltage and High Vacuum Led to "Modern Physics"

    NASA Astrophysics Data System (ADS)

    Greenslade, Thomas B.

    2018-05-01

    Some of you may remember the 1979 television series "Connections" that was written and narrated by James Burke, a British science writer. Burke's technique was to choose a number of seemingly unrelated ideas and show how they led to developments in science and technology. This is an enjoyable business, even if some of the connections seem to be stretched at times, and led to a book by Burke. In a number of talks that I have given over the years, I have made somewhat less fanciful connections that suggest how the technologies of high vacuum and high voltage led to what used to be called "modern physics." Today we might limit the "modern" era to the years from 1890 to 1920 that gave the first workable theories of small-scale physics.

  8. Origins of modern premedical education.

    PubMed

    Fishbein, R H

    2001-05-01

    The author reviews the contributions of those individuals and major academic and professional organizations responsible for the development of the modern concepts of the premedical education of a physician. The late 19th century gave rise to scientifically-based medical education in U.S. medical education. It followed that this new emphasis, in medical schools, on laboratory investigation of disease processes demanded a sound introduction to the natural sciences by those who would be candidates for this type of challenging education. Starting with a vocal few, the message gradually was received throughout the country that a properly schooled physician must have the equivalent of a broad baccalaureate education in the natural sciences as well as in the traditional humanities. This essential was recognized by a small nucleus of individuals responsible for the creation of The Johns Hopkins University in 1876 and its school of medicine in 1893; the group was led by the university's first president, Daniel Coit GILMAN: Almost simultaneously other established academic institutions incorporated similar changes and a new era began.

  9. Structural insights into cell cycle control by essential GTPase Era.

    PubMed

    Ji, Xinhua

    Era (Escherichia coli Ras-like protein), essential for bacterial cell viability, is composed of an N-terminal GTPase domain and a C-terminal KH domain. In bacteria, it is required for the processing of 16S ribosomal RNA (rRNA) and maturation of 30S (small) ribosomal subunit. Era recognizes 10 nucleotides ( 1530 GAUCACCUCC 1539 ) near the 3' end of 16S rRNA and interacts with helix 45 (h45, nucleotides 1506-1529). GTP binding enables Era to bind RNA, RNA binding stimulates Era's GTP-hydrolyzing activity, and GTP hydrolysis releases Era from matured 30S ribosomal subunit. As such, Era controls cell growth rate via regulating the maturation of the 30S ribosomal subunit. Ribosomes manufacture proteins in all living organisms. The GAUCA sequence and h45 are highly conserved in all three kingdoms of life. Homologues of Era are present in eukaryotic cells. Hence, the mechanism of bacterial Era action also sheds light on the cell cycle control of eukaryotes.

  10. Intelligence in the Internet Era

    DTIC Science & Technology

    2003-01-01

    and the enhanced exploitation capabili ties that information technology and the Internet give our adver saries. NSA�s Director, Lt. Gen. Michael Hayden...From Semaphore to Predator Intelligence in the Internet Era A. Denis Clift Actionable information from around the globe is today the air we breathe... Technology / Internet era: �What it all boils down to is that faster, smaller, cheaper elec tro-optical digital technologies have put into our hands enor

  11. NASA #801 and NASA 7 on ramp

    NASA Technical Reports Server (NTRS)

    1997-01-01

    NASA N801NA and NASA 7 together on the NASA Dryden ramp. The Beechcraft Beech 200 Super KingAir aircraft N7NA, known as NASA 7, has been a support aircraft for many years, flying 'shuttle' missions to Ames Research Center. It once flew from the Jet Propulsion Laboratory and back each day but now (2001) flies between the Dryden Flight Research Center and Ames. A second Beechcraft Beech 200 Super King Air, N701NA, redesignated N801NA, transferred to Dryden on 3 Oct. 1997 and is used for research missions but substitutes for NASA 7 on shuttle missions when NASA 7 is not available.

  12. Storm-Tracks in ERA-40 and ERA-Interim Reanalyses

    NASA Astrophysics Data System (ADS)

    Liberato, M. L. R.; Trigo, I. F.; Trigo, R. M.

    2009-04-01

    Extratropical cyclones, their dominant paths, frequency and intensity have long been the object of climatological studies. The analysis of cyclone characteristics for the Euro-Atlantic sector (85°W-70°E; 20°N-75°N) presented here is based on the cyclone detecting and tracking algorithm first developed for the Mediterranean region (Trigo et al., 1999, 2002) and recently extended to a larger Euro-Atlantic region (Trigo, 2006). The objective methodology, which identifies and follows individual lows (Trigo et al. 1999), is applied to 6-hourly geopotential data at 1000-hPa from two reanalyses datasets provided by the European Centre for Medium-Range Weather Forecasts (ECMWF): ERA-40 and ERA-Interim reanalyses. Two storm-track databases are built over the Northern Atlantic European area, spanning the common available extended winter seasons from October 1989 to March 2002. Although relatively short, this common period allows a comparison of systems represented in reanalyses datasets with distinct horizontal resolutions (T106 and T255, respectively). This exercise is mostly focused on the key areas of cyclone formation and dissipation and main cyclone characteristics for the Euro-Atlantic sector. Trigo, I. F., T. D. Davies, and G. R. Bigg, 1999: Objective climatology of cyclones in the Mediterranean region. J. Climate, 12, 1685-1696. Trigo I. F., G. R. Bigg and T. D. Davies, 2002: Climatology of Cyclogenesis Mechanisms in the Mediterranean. Mon. Weather Rev. 130, 549-569. Trigo, I. F. 2006: Climatology and Interannual Variability of Storm-Tracks in the Euro-Atlantic sector: a comparison between ERA-40 and NCEP/NCAR Reanalyses. Clim. Dyn. DOI 10.1007/s00382-005-0065-9.

  13. [The development of the Japanese pharmaceutical industry (part 7). Histories of medical advertisements from Taisho Era till Showa Era].

    PubMed

    Takehara, J; Yamada, H

    1999-01-01

    Medical advertisements in newspapers have been used quite often as a means of sales promotion since the Meiji Era. Medical advertisements were quantitatively the leading advertisements in Japanese newspapers from the Taisho Era to early in the Showa Era. When World War II broke out, the quanity of advertisements in newspapers decreased markedly. After the war ended, the quantity of radio commercials for medicine increased quite rapidly. In the 1960s, however, pharmaceutical companies were criticized for over-promoting and improperly using medicines.

  14. Six Decades of Flight Research: Dryden Flight Research Center, 1946 - 2006 [DVD

    NASA Technical Reports Server (NTRS)

    Fisher, David F.; Parcel, Steve

    2007-01-01

    This DVD contains an introduction by Center Director Kevin Peterson, two videos on the history of NASA Dryden Flight Research Center and a bibliography of NASA Dryden Flight Research Center publications from 1946 through 2006. The NASA Dryden 60th Anniversary Summary Documentary video is narrated by Michael Dorn and give a brief history of Dryden. The Six Decades of Flight Research at NASA Dryden lasts approximately 75 minutes and is broken up in six decades: 1. The Early X-Plane Era; 2. The X-15 Era; 3. The Lifting Body Era; 4. The Space Shuttle Era; 5. The High Alpha and Thrust Vectoring Era; and 6. The technology Demonstration Era. The bibliography provides citations for NASA Technical Reports and Conference Papers, Tech Briefs, Contractor Reports, UCLA Flight Systems Research Center publications and Dryden videos. Finally, a link is provided to the NASA Dryden Gallery that features video clips and photos of the many unique aircraft flown at NASA Dryden and its predecessor organizations.

  15. Orion Spacecraft Parachute Test on This Week @NASA – March 10, 2017

    NASA Image and Video Library

    2017-03-10

    NASA conducted the latest successful test of the Orion spacecraft’s parachute system on March 8 in the skies above the U.S. Army’s Yuma Proving Ground in Arizona. The test was designed to evaluate the parachutes’ performance in an emergency abort situation that would require Orion to be jettisoned from the agency’s Space Launch System rocket during a launch. Even at this relatively low altitude, the parachutes are designed to fully deploy and safely return Orion and its crew to Earth. Also, Shin Honored by Aviation Week, Space Station Resupply Mission Targeted for March 19, Small Business Innovation Proposals Selected, Deep Space Atomic Clock, Modern Figures Virtual Tour, and NASA Aero “Night of Flight”!

  16. Snow Accumulation Variability Over the West Antarctic Ice Sheet Since 1900: A Comparison of Ice Core Records With ERA-20C Reanalysis

    NASA Astrophysics Data System (ADS)

    Wang, Yetang; Thomas, Elizabeth R.; Hou, Shugui; Huai, Baojuan; Wu, Shuangye; Sun, Weijun; Qi, Shanzhong; Ding, Minghu; Zhang, Yulun

    2017-11-01

    This study uses a set of 37 firn core records over the West Antarctic Ice Sheet (WAIS) to test the performance of the twentieth century from the European Centre for Medium-Range Weather Forecasts (ERA-20C) reanalysis for snow accumulation and quantify temporal variability in snow accumulation since 1900. The firn cores are allocated to four geographical areas demarcated by drainage divides (i.e., Antarctic Peninsula (AP), western WAIS, central WAIS, and eastern WAIS) to calculate stacked records of regional snow accumulation. Our results show that the interannual variability in ERA-20C precipitation minus evaporation (P - E) agrees well with the corresponding ice core snow accumulation composites in each of the four geographical regions, suggesting its skill for simulating snow accumulation changes before the modern satellite era (pre-1979). Snow accumulation experiences significantly positive trends for the AP and eastern WAIS, a negative trend for the western WAIS, and no significant trend for the central WAIS from 1900 to 2010. The contrasting trends are associated with changes in the large-scale moisture transport driven by a deepening of the low-pressure systems and anomalies of sea ice in the Amundsen Sea Low region.

  17. Revisiting Mathematical Problem Solving and Posing in the Digital Era: Toward Pedagogically Sound Uses of Modern Technology

    ERIC Educational Resources Information Center

    Abramovich, S.

    2014-01-01

    The availability of sophisticated computer programs such as "Wolfram Alpha" has made many problems found in the secondary mathematics curriculum somewhat obsolete for they can be easily solved by the software. Against this background, an interplay between the power of a modern tool of technology and educational constraints it presents is…

  18. NASA Update

    NASA Image and Video Library

    2011-02-15

    NASA Administrator Charles F. Bolden Jr., answers questions during a NASA Update on, Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and NASA Deputy Administrator Lori Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

  19. To Boldly Go: America's Next Era in Space. The Universe Now and Beyond

    NASA Technical Reports Server (NTRS)

    2004-01-01

    Dr. France Cordova, NASA's Chief Scientist opened this, the third session in the NASA Administrator's Seminar Series, by asking the following question: 'What would be a bold and aspiring agenda for America's next era in space?' It aimed at answering the following questions: What do we know about the universe? How do we know it? (Dr. Cordova also mentioned that the first seminar was about the definition of cellular life and how to recognize it, and featured as speakers, Dr. Lynn Margoles and Dr. Leslie Orgle.) Administrator Daniel S. Goldin was introduced; he welcomed the attendees, and remarked that NASA personnel have a critical need to explain to Congress and the public why a space program is important. Congress and the public pay for the space programs. Therefore the programs' importance cannot remain in the sole domain of scientists. The first speaker, Dr. Vera Ruben of the Department of Terrestrial Magnetism at the Carnegie Institute of Washington, was introduced as an art historian expert in cosmology and an observational astronomer. Dr. Ruben brought up a number of questions regarding the substance, location, and origin of dark matter, radiation, galaxies, and the lumpy structure of galaxies in space, as well as the age and density of our universe. The next speaker was Dr. Bohdan Paczynski, a theoretical astrophysicist from Princeton University's Department of Astrophysical Sciences. The final speaker, Dr. Linda Schale is a cosmologist from the University of Texas at Austin. She was said to be a 'paleontologist of the human mind' who tries 'to understand mechanisms people use to understand the world'. The concluding discussion centered on why NASA scientists don t communicate better with people who are not highly educated. This is a big concern because to continue its work, NASA needs to communicate the importance of its goals to the average person. Additional information is included in the original extended abstract.

  20. Hepatic Arterial Infusion in Combination with Modern Systemic Chemotherapy is Associated with Improved Survival Compared with Modern Systemic Chemotherapy Alone in Patients with Isolated Unresectable Colorectal Liver Metastases: A Case-Control Study.

    PubMed

    Dhir, Mashaal; Jones, Heather L; Shuai, Yongli; Clifford, Amber K; Perkins, Samantha; Steve, Jennifer; Hogg, Melissa E; Choudry, M Haroon A; Pingpank, James F; Holtzman, Matthew P; Zeh, Herbert J; Bahary, Nathan; Bartlett, David L; Zureikat, Amer H

    2017-01-01

    In the era of effective modern systemic chemotherapy (CT), the role of hepatic arterial infusion of fluoxuridine (HAI-FUDR) in the treatment of isolated unresectable colorectal liver metastasis (IU-CRCLM) remains controversial. This study aimed to compare the overall survival (OS) of HAI-FUDR in combination with modern systemic CT versus modern systemic CT alone in patients with IU-CRCLM. This was a case-control study of IU-CRCLM patients who underwent HAI + modern systemic CT or modern systemic CT alone. Modern systemic CT was defined as the use of multidrug regimens containing oxaliplatin and/or irinotecan ± biologics. Overall, 86 patients met the inclusion criteria (n = 40 for the HAI + CT group, and n = 46 for the CT-alone group). Both groups were similar in demographics, primary and stage IV tumor characteristics, and treatment-related variables (carcinoembryonic antigen, use of biologic agents, total number of lines of systemic CT administered) (all p > 0.05). Additionally, both groups were comparable with respect to liver tumor burden [median number of lesions (13.5 vs. 15), percentage of liver tumor replacement (37.5 vs. 40 %), and size of largest lesion] (all p > 0.05). Median OS in the HAI + CT group was 32.8 months compared with 15.3 months in the CT-alone group (p < 0.0001). Multivariate analysis revealed HAI + CT (hazard ratio 0.4, 95 % confidence interval 0.21-0.72; p = 0.003), Eastern Cooperative Oncology Group status, and receipt of increasing number of lines of systemic CT to be independent predictors of survival. In this case-control study of patients with IU-CRCLM, HAI in combination with CT was associated with improved OS when compared with modern systemic CT alone.

  1. Development of an Outreach Program for NASA: "NASA Ambassadors"

    NASA Technical Reports Server (NTRS)

    Lebo, George R.

    1996-01-01

    It is widely known that the average American citizen has either no idea or the wrong impression of what NASA is doing. The most common impression is that NASA's sole mission is to build and launch spacecraft and that the everyday experience of the common citizen would be impacted very little if NASA failed to exist altogether. Some feel that most of NASA's efforts are much too expensive and that the money would be better used on other efforts. Others feel that most of NASA's efforts either fail altogether or fail to meet their original objectives. Yet others feel that NASA is so mired in bureaucracy that it is no longer able to function. The goal of the NASA Ambassadors Program (NAP) is to educate the general populace as to what NASA's mission and goals actually are, to re-excite the "man on the street" with NASA's discoveries and technologies, and to convince him that NASA really does impact his everyday experience and that the economy of the U.S. is very dependent on NASA-type research. Each of the NASA centers currently run a speakers bureau through its Public Affairs Office (PAO). The speakers, NASA employees, are scheduled on an "as available" status and their travel is paid by NASA. However, there are only a limited number of them and their message may be regarded as being somewhat biased as they are paid by NASA. On the other hand, there are many members of NASA's summer programs which come from all areas of the country. Most of them not only believe that NASA's mission is important but are willing and able to articulate it to others. Furthermore, in the eyes of the public, they are probably more effective as ambassadors for NASA than are the NASA employees, as they do not derive their primary funding from it. Therefore it was decided to organize materials for them to use in presentations to general audiences in their home areas. Each person who accepted these materials was to be called a "NASA Ambassador".

  2. Air Traffic Management Research at NASA

    NASA Technical Reports Server (NTRS)

    Farley, Todd

    2012-01-01

    The U.S. air transportation system is the most productive in the world, moving far more people and goods than any other. It is also the safest system in the world, thanks in part to its venerable air traffic control system. But as demand for air travel continues to grow, the air traffic control systems aging infrastructure and labor-intensive procedures are impinging on its ability to keep pace with demand. And that impinges on the growth of our economy. Part of NASA's current mission in aeronautics research is to invent new technologies and procedures for ATC that will enable our national airspace system to accommodate the increasing demand for air transportation well into the next generation while still maintaining its excellent record for safety. It is a challenging mission, as efforts to modernize have, for decades, been hamstrung by the inability to assure safety to the satisfaction of system operators, system regulators, and/or the traveling public. In this talk, we'll provide a brief history of air traffic control, focusing on the tension between efficiency and safety assurance, and we'll highlight some new NASA technologies coming down the pike.

  3. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Deputy Administrator Lori Garver, right, looks on as NASA Administrator Charles F. Bolden Jr. speaks during his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  4. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Deputy Administrator Lori Garver, second right on stage, speaks as NASA Administrator Charles F. Bolden Jr. looks on during a NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  5. Mortality risk factors show similar trends in modern and historic populations exposed to plague.

    PubMed

    Rubini, Mauro; Gualdi-Russo, Emanuela; Manzon, Vanessa S; Rinaldo, Natascia; Bianucci, Raffaella

    2016-05-31

    Plague has been responsible for two major historic pandemics (6th-8th century CE; 14th-19th century CE) and a modern one. The recent Malagasy plague outbreaks raised new concerns on the deadly potential of the plague-causing bacteria Yersinia pestis. Between September 2014 and April 2015, outbreaks of bubonic and pneumonic plague hit the Malagasy population. Two hundred and sixty-three cases, including 71 deaths, have been reported in 16 different districts with a case fatality rate of 27%. The scope of our study was to ascertain whether the risk factors for health in modern-day populations exposed to plague and in ancient populations that faced the two historic pandemics varied or remained substantially unaltered. The risk of mortality of the Malagasy population with those obtained from the reconstruction of three samples of European populations exposed to the historic pandemics was contrasted. The evidence shows that the risks of death are not uniform across age neither in modern nor in historic populations exposed to plague and shows precise concentrations in specific age groups (children between five and nine years of age and young adults). Although in the post-antibiotic era, the fatality rates have drastically reduced, both modern and historic populations were exposed to the same risk factors that are essentially represented by a low standard of environmental hygiene, poor nutrition, and weak health systems.

  6. Steel Construction of Modern Building of Former Sports Hall at Chopin Street in Zielona Góra

    NASA Astrophysics Data System (ADS)

    Michalak, Bartosz

    2016-06-01

    Modernism in architecture of the lubuskie voivodeship is not dominating style. Objects created in the period of its greatest popularity are still fighting for recognition of their value as historical monuments. One of such facilities in Zielona Góra is building at Chopin street, where today is The Teacher Training Centre. However, originally object was intended to be a sports hall. The topic worth of further analysis is the construction of the building. The skeleton is a unique steel frame, made in 1930 by the famous pre-war company Fabrik und für Brückenbau Eisenkonstruktionen BEUCHELT & Co. Grünberg in Schlesien. In order to build walls the brick technology was used. It is a rarely seen combination that indicates the attempt to experiment with new solutions by engineers of the era of modernism.

  7. NASA Update.

    NASA Image and Video Library

    2011-02-15

    NASA Deputy Administrator Lori Garver answers questions during a NASA Update on, Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Garver and NASA Administrator Charles Bolden took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

  8. Implementation of the Spanish ERAS program in bariatric surgery.

    PubMed

    Ruiz-Tovar, Jaime; Muñoz, José Luis; Royo, Pablo; Duran, Manuel; Redondo, Elisabeth; Ramirez, Jose Manuel

    2018-03-08

    The essence of Enhanced Recovery After Surgery (ERAS) programs is the multimodal approach, and many authors have demonstrated safety and feasibility in fast track bariatric surgery. According to this concept, a multidisciplinary ERAS program for bariatric surgery has been developed by the Spanish Fast Track Group (ERAS Spain). The aim of this study was to analyze the initial implementation of this Spanish National ERAS protocol in bariatric surgery, comparing it with a historical cohort receiving standard care. A multi-centric prospective study was performed, including 233 consecutive patients undergoing bariatric surgery during 2015 and following ERAS protocol. It was compared with a historical cohort of 286 patients, who underwent bariatric surgery at the same institutions between 2013 and 2014 and following standard care. Compliance with the protocol, morbidity, mortality, hospital stay and readmission were evaluated. Bariatric techniques performed were Roux-en-Y gastric bypass and sleeve gastrectomy. There were no significant differences in complications, mortality and readmission. Postoperative pain and hospital stay were significantly lower in the ERAS group. The total compliance to protocol was 80%. The Spanish National ERAS protocol is a safe issue, obtaining similar results to standard care in terms of complications, reoperations, mortality and readmissions. It is associated with less postoperative pain and earlier hospital discharge.

  9. NASA Update

    NASA Image and Video Library

    2009-07-20

    Alan Ladwig, senior advisor to the NASA Administator, far left, makes a point as he introduces NASA Administrator Charles F. Bolden Jr. and Deputy Administrator Lori Garver at a NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  10. The modern rotor aerodynamic limits survey: A report and data survey

    NASA Technical Reports Server (NTRS)

    Cross, J.; Brilla, J.; Kufeld, R.; Balough, D.

    1993-01-01

    The first phase of the Modern Technology Rotor Program, the Modern Rotor Aerodynamic Limits Survey, was a flight test conducted by the United States Army Aviation Engineering Flight Activity for NASA Ames Research Center. The test was performed using a United States Army UH-60A Black Hawk aircraft and the United States Air Force HH-60A Night Hawk instrumented main-rotor blade. The primary purpose of this test was to gather high-speed, steady-state, and maneuvering data suitable for correlation purposes with analytical prediction tools. All aspects of the data base, flight-test instrumentation, and test procedures are presented and analyzed. Because of the high volume of data, only select data points are presented. However, access to the entire data set is available upon request.

  11. Optimal Access to NASA Water Cycle Data for Water Resources Management

    NASA Astrophysics Data System (ADS)

    Teng, W. L.; Arctur, D. K.; Espinoza, G. E.; Rui, H.; Strub, R. F.; Vollmer, B.

    2016-12-01

    A "Digital Divide" in data representation exists between the preferred way of data access by the hydrology community (i.e., as time series of discrete spatial objects) and the common way of data archival by earth science data centers (i.e., as continuous spatial fields, one file per time step). This Divide has been an obstacle, specifically, between the Consortium of Universities for the Advancement of Hydrologic Science, Inc. Hydrologic Information System (CUAHSI HIS) and NASA Goddard Earth Sciences Data and Information Services Center (GES DISC). An optimal approach to bridging the Divide, developed by the GES DISC, is to reorganize data from the way they are archived to some way that is optimal for the desired method of data access. Specifically for CUAHSI HIS, selected data sets were reorganized into time series files, one per geographical "point." These time series files, termed "data rods," are pre-generated or virtual (generated on-the-fly). Data sets available as data rods include North American Land Data Assimilation System (NLDAS), Global Land Data Assimilation System (GLDAS), TRMM Multi-satellite Precipitation Analysis (TMPA), Land Parameter Retrieval Model (LPRM), Modern-Era Retrospective Analysis for Research and Applications (MERRA)-Land, and Groundwater and Soil Moisture Conditions from Gravity Recovery and Climate Experiment (GRACE) Data Assimilation drought indicators for North America Drought Monitor (GRACE-DA-DM). In order to easily avail the operational water resources community the benefits of optimally reorganized data, we have developed multiple methods of making these data more easily accessible and usable. These include direct access via RESTful Web services, a browser-based Web map and statistical tool for selected NLDAS variables for the U.S. (CONUS), a HydroShare app (Data Rods Explorer, under development) on the Tethys Platform, and access via the GEOSS Portal. Examples of drought-related applications of these data and data access

  12. Evaluation and inter-comparison of modern day reanalysis datasets over Africa and the Middle East

    NASA Astrophysics Data System (ADS)

    Shukla, S.; Arsenault, K. R.; Hobbins, M.; Peters-Lidard, C. D.; Verdin, J. P.

    2015-12-01

    Reanalysis datasets are potentially very valuable for otherwise data-sparse regions such as Africa and the Middle East. They are potentially useful for long-term climate and hydrologic analyses and, given their availability in real-time, they are particularity attractive for real-time hydrologic monitoring purposes (e.g. to monitor flood and drought events). Generally in data-sparse regions, reanalysis variables such as precipitation, temperature, radiation and humidity are used in conjunction with in-situ and/or satellite-based datasets to generate long-term gridded atmospheric forcing datasets. These atmospheric forcing datasets are used to drive offline land surface models and simulate soil moisture and runoff, which are natural indicators of hydrologic conditions. Therefore, any uncertainty or bias in the reanalysis datasets contributes to uncertainties in hydrologic monitoring estimates. In this presentation, we report on a comprehensive analysis that evaluates several modern-day reanalysis products (such as NASA's MERRA-1 and -2, ECMWF's ERA-Interim and NCEP's CFS Reanalysis) over Africa and the Middle East region. We compare the precipitation and temperature from the reanalysis products with other independent gridded datasets such as GPCC, CRU, and USGS/UCSB's CHIRPS precipitation datasets, and CRU's temperature datasets. The evaluations are conducted at a monthly time scale, since some of these independent datasets are only available at this temporal resolution. The evaluations range from the comparison of the monthly mean climatology to inter-annual variability and long-term changes. Finally, we also present the results of inter-comparisons of radiation and humidity variables from the different reanalysis datasets.

  13. NASA Quest.

    ERIC Educational Resources Information Center

    Ashby, Susanne

    2000-01-01

    Introduces NASA Quest as part of NASA's Learning Technologies Project, which connects students to the people of NASA through the various pages at the website where students can glimpse the various types of work performed at different NASA facilities and talk to NASA workers about the type of work they do. (ASK)

  14. Global aquifers dominated by fossil groundwaters but wells vulnerable to modern contamination

    NASA Astrophysics Data System (ADS)

    Jasechko, Scott; Perrone, Debra; Befus, Kevin M.; Bayani Cardenas, M.; Ferguson, Grant; Gleeson, Tom; Luijendijk, Elco; McDonnell, Jeffrey J.; Taylor, Richard G.; Wada, Yoshihide; Kirchner, James W.

    2017-06-01

    The vulnerability of groundwater to contamination is closely related to its age. Groundwaters that infiltrated prior to the Holocene have been documented in many aquifers and are widely assumed to be unaffected by modern contamination. However, the global prevalence of these `fossil' groundwaters and their vulnerability to modern-era pollutants remain unclear. Here we analyse groundwater carbon isotope data (12C, 13C, 14C) from 6,455 wells around the globe. We show that fossil groundwaters comprise a large share (42-85%) of total aquifer storage in the upper 1 km of the crust, and the majority of waters pumped from wells deeper than 250 m. However, half of the wells in our study that are dominated by fossil groundwater also contain detectable levels of tritium, indicating the presence of much younger, decadal-age waters and suggesting that contemporary contaminants may be able to reach deep wells that tap fossil aquifers. We conclude that water quality risk should be considered along with sustainable use when managing fossil groundwater resources.

  15. Factors affecting food security and contribution of modern technologies in food sustainability.

    PubMed

    Premanandh, Jagadeesan

    2011-12-01

    The concept of food insecurity is complex and goes beyond the simplistic idea of a country's inability to feed its population. The global food situation is redefined by many driving forces such as population growth, availability of arable lands, water resources, climate change and food availability, accessibility and loss. The combined effect of these factors has undeniably impacted global food production and security. This article reviews the key factors influencing global food insecurity and emphasises the need to adapt science-based technological innovations to address the issue. Although anticipated benefits of modern technologies suggest a level of food production that will sustain the global population, both political will and sufficient investments in modern agriculture are needed to alleviate the food crisis in developing countries. In this globalised era of the 21st century, many determinants of food security are trans-boundary and require multilateral agreements and actions for an effective solution. Food security and hunger alleviation on a global scale are within reach provided that technological innovations are accepted and implemented at all levels. Copyright © 2011 Society of Chemical Industry.

  16. NASA Plum Brook's B-2 Test Facility: Thermal Vacuum and Propellant Test Facility

    NASA Technical Reports Server (NTRS)

    Kudlac, Maureen T.; Weaver, Harold F.; Cmar, Mark D.

    2012-01-01

    The National Aeronautics and Space Administration (NASA) Glenn Research Center (GRC) Plum Brook Station (PBS) Spacecraft Propulsion Research Facility, commonly referred to as B-2, is NASA's third largest thermal vacuum facility. It is the largest designed to store and transfer large quantities of liquid hydrogen and liquid oxygen, and is perfectly suited to support developmental testing of upper stage chemical propulsion systems as well as fully integrated stages. The facility is also capable of providing thermal-vacuum simulation services to support testing of large lightweight structures, Cryogenic Fluid Management (CFM) systems, electric propulsion test programs, and other In-Space propulsion programs. A recently completed integrated system test demonstrated the refurbished thermal vacuum capabilities of the facility. The test used the modernized data acquisition and control system to monitor the facility. The heat sink provided a uniform temperature environment of approximately 77 K. The modernized infrared lamp array produced a nominal heat flux of 1.4 kW/sq m. With the lamp array and heat sink operating simultaneously, the thermal systems produced a heat flux pattern simulating radiation to space on one surface and solar exposure on the other surface.

  17. NASA Update

    NASA Image and Video Library

    2011-02-15

    NASA Administrator Charles F. Bolden Jr., and Deputy Administrator Lori Garver deliver a NASA Update on, Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

  18. NASA Update

    NASA Image and Video Library

    2011-02-15

    NASA Deputy Administrator Lori Garver listens as NASA Administrator Charles Bolden answers a question during a NASA Update on Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Bolden and Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

  19. Bilateral Simultaneous Ureteroscopic (BS-URS) Approach in the Management of Bilateral Urolithiasis Is a Safe and Effective Strategy in the Contemporary Era-Evidence from a Systematic Review.

    PubMed

    Geraghty, Robert M; Rai, Bhavan P; Jones, Patrick; Somani, Bhaskar K

    2017-02-01

    Ureteroscopic treatment of urolithiasis has become safer and more effective in the modern era. With a rise in the incidence of bilateral urolithiasis, management dilemma of staged single-side ureteroscopy versus bilateral simultaneous ureteroscopy (BS-URS) is often debatable. This review evaluates the current evidence base for bilateral simultaneous ureteroscopic approach in the modern era. A systematic review was conducted from 1990 to June 2016 including all English language articles reporting on outcomes of BS-URS for urolithiasis. Data was split into two periods: period 1: 2003-2012 and period 2: 2013-2016, and analysed using SPSS version 21. A total of 11 studies (491 patients) were identified from a literature search of 148 studies with mean age of 45 years and a male: female ratio of 2:1 and a mean operative time of 69 min (SD = ±15). The initial and final stone-free rate (SFR) was 87 and 93%, respectively. Post-operative stents were placed in 89% of patients with a mean hospital stay of 1.6 days (SD = ±0.5). Overall, there was a significant negative association between case volume (procedures per month) and complication rate (p = 0.045). Mean hospital stay was significantly longer in period 1 (1.9 days, SD = ±0.5) than period 2 (1.3 days, SD = ±0.3) and complications were also significantly higher in period 1 (47%) compared to period 2 (12%) (p < 0.001). There were six studies examining holmium laser (HL) lithotripsy and three examining pneumatic lithotripsy (PL). There were significantly more complications after PL than HL; however, their SFR was similar. Our review shows that the complication rates and hospital stay are significantly reduced in the contemporary data suggesting an improving trend in outcomes following BS-URS. Simultaneous bilateral ureteroscopic treatment of urolithiasis is safe and effective in the modern era. Safety is increased in centers with increased number of procedures performed and with laser

  20. NASA Update

    NASA Image and Video Library

    2011-02-15

    NASA Deputy Associate Administrator for the Office of Communications Bob Jacobs moderates the NASA Update program, Tuesday, Feb. 15, 2011 at NASA Headquarters in Washington. NASA's 12th Administrator Charles Bolden and Deputy Administrator Lori Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

  1. Feasibility of modern airships - Preliminary assessment

    NASA Technical Reports Server (NTRS)

    Ardema, M. D.

    1977-01-01

    Attention is given to the NASA program, Feasibility Study of Modern Airships, initiated to investigate potential research and technology programs associated with airship development. A historical survey of the program is presented, including the development of past airship concepts, aerodynamical and design improvements, structure and material concepts, and research in controls, avionics, instrumentation, flight operations, and ground handling. A mission analysis was carried out which considered passenger and cargo transportation, heavy-lift, short-haul applications, surveillance missions, and the transportation of natural gas. A vehicle parametric analysis examined the entire range of airship concepts, discussing both conventional airships and hybrids. Various design options were evaluated, such as choice of structural materials, use of boundary-layer control, and choice of lifting gas.

  2. Seasonal scale water deficit forecasting in Africa and the Middle East using NASA's Land Information System (LIS)

    NASA Astrophysics Data System (ADS)

    Shukla, Shraddhanand; Arsenault, Kristi R.; Getirana, Augusto; Kumar, Sujay V.; Roningen, Jeanne; Zaitchik, Ben; McNally, Amy; Koster, Randal D.; Peters-Lidard, Christa

    2017-04-01

    Drought and water scarcity are among the important issues facing several regions within Africa and the Middle East. A seamless and effective monitoring and early warning system is needed by regional/national stakeholders. Such system should support a proactive drought management approach and mitigate the socio-economic losses up to the extent possible. In this presentation, we report on the ongoing development and validation of a seasonal scale water deficit forecasting system based on NASA's Land Information System (LIS) and seasonal climate forecasts. First, our presentation will focus on the implementation and validation of the LIS models used for drought and water availability monitoring in the region. The second part will focus on evaluating drought and water availability forecasts. Finally, details will be provided of our ongoing collaboration with end-user partners in the region (e.g., USAID's Famine Early Warning Systems Network, FEWS NET), on formulating meaningful early warning indicators, effective communication and seamless dissemination of the monitoring and forecasting products through NASA's web-services. The water deficit forecasting system thus far incorporates NOAA's Noah land surface model (LSM), version 3.3, the Variable Infiltration Capacity (VIC) model, version 4.12, NASA GMAO's Catchment LSM, and the Noah Multi-Physics (MP) LSM (the latter two incorporate prognostic water table schemes). In addition, the LSMs' surface and subsurface runoff are routed through the Hydrological Modeling and Analysis Platform (HyMAP) to simulate surface water dynamics. The LSMs are driven by NASA/GMAO's Modern-Era Retrospective analysis for Research and Applications, Version 2 (MERRA-2), and the USGS and UCSB Climate Hazards Group InfraRed Precipitation with Station (CHIRPS) daily rainfall dataset. The LIS software framework integrates these forcing datasets and drives the four LSMs and HyMAP. The Land Verification Toolkit (LVT) is used for the evaluation of the

  3. NASA's Space Launch System: An Enabling Capability for International Exploration

    NASA Technical Reports Server (NTRS)

    Creech, Stephen D.; May, Todd A.; Robinson, Kimberly F.

    2014-01-01

    As the program moves out of the formulation phase and into implementation, work is well underway on NASA's new Space Launch System, the world's most powerful launch vehicle, which will enable a new era of human exploration of deep space. As assembly and testing of the rocket is taking place at numerous sites around the United States, mission planners within NASA and at the agency's international partners continue to evaluate utilization opportunities for this ground-breaking capability. Developed with the goals of safety, affordability, and sustainability in mind, the SLS rocket will launch the Orion Multi-Purpose Crew Vehicle (MPCV), equipment, supplies, and major science missions for exploration and discovery. NASA is developing this new capability in an austere economic climate, a fact which has inspired the SLS team to find innovative solutions to the challenges of designing, developing, fielding, and operating the largest rocket in history, via a path that will deliver an initial 70 metric ton (t) capability in December 2017 and then continuing through an incremental evolutionary strategy to reach a full capability greater than 130 t. SLS will be enabling for the first missions of human exploration beyond low Earth in almost half a century, and from its first crewed flight will be able to carry humans farther into space than they have ever voyaged before. In planning for the future of exploration, the International Space Exploration Coordination Group, representing 12 of the world's space agencies, has created the Global Exploration Roadmap, which outlines paths toward a human landing on Mars, beginning with capability-demonstrating missions to the Moon or an asteroid. The Roadmap and corresponding NASA research outline the requirements for reference missions for these destinations. SLS will offer a robust way to transport international crews and the air, water, food, and equipment they would need for such missions.

  4. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Administrator Charles F. Bolden Jr. left, speaks during his first NASA Update as Deputy Administrator Lori Garver looks on,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  5. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Administrator Charles F. Bolden Jr. left, and Deputy Administrator Lori Garver are seen during their first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  6. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Administrator Charles F. Bolden Jr. speaks during his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator, was joined by Deputy Administrator Lori Garver where they took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  7. Complexity analysis of the cost effectiveness of PI-led NASA science missions

    NASA Astrophysics Data System (ADS)

    Yoshida, J.; Cowdin, M.; Mize, T.; Kellogg, R.; Bearden, D.

    For the last 20 years, NASA has allowed Principal Investigators (PIs) to manage the development of many unmanned space projects. Advocates of PI-led projects believe that a PI-led implementation can result in a project being developed at lower cost and shorter schedule than other implementation modes. This paper seeks to test this hypothesis by comparing the actual costs of NASA and other comparable projects developed under different implementation modes. The Aerospace Corporation's Complexity-Based Risk Assessment (CoBRA) analysis tool is used to normalize the projects such that the cost can be compared for equivalent project complexities. The data is examined both by complexity and by launch year. Cost growth will also be examined for any correlation with implementation mode. Defined in many NASA Announcements of Opportunity (AOs), a PI-led project is characterized by a central, single person with full responsibility for assembling a team and for the project's scientific integrity and the implementation and integrity of all other aspects of the mission, while operating under a cost cap. PIs have larger degrees of freedom to achieve the stated goals within NASA guidelines and oversight. This study leverages the definitions and results of previous National Research Council studies of PI-led projects. Aerospace has defined a complexity index, derived from mission performance, mass, power, and technology choices, to arrive at a broad representation of missions for purposes of comparison. Over a decade of research has established a correlation between mission complexity and spacecraft development cost and schedule. This complexity analysis, CoBRA, is applied to compare a PI-led set of New Frontiers, Discovery, Explorers, and Earth System Science Pathfinder missions to the overall NASA mission dataset. This reveals the complexity trends against development costs, cost growth, and development era.

  8. Stewardship of NASA's Earth Science Data and Ensuring Long-Term Active Archives

    NASA Astrophysics Data System (ADS)

    Ramapriyan, H.; Behnke, J.

    2016-12-01

    NASA's Earth Observing System Data and Information System (EOSDIS) has been in operation since 1994. EOSDIS manages data from pre-EOS missions dating back to 1960s, EOS missions that started in 1997, and missions from the post-EOS era. Its data holdings come from many different sources - satellite and airborne instruments, in situ measures, field experiments, science investigations, etc. Since the beginning of the EOS Program, NASA has followed an open data policy, with non-discriminatory access to data with no period of exclusive access. NASA has well-established processes for assigning and/or accepting datasets into one of 12 Distributed Active Archive Centers (DAACs) that are parts of EOSDIS. EOSDIS has been evolving through several information technology cycles, adapting to hardware and software changes in the commercial sector. NASA is responsible for maintaining Earth science data as long as users are interested in using them for research and applications, which is well beyond the life of the data gathering missions. For science data to remain useful over long periods of time, steps must be taken to preserve: 1. Data bits with no corruption, 2. Discoverability and access, 3. Readability, 4. Understandability, 5. Usability and 6. Reproducibility of results. NASA's Earth Science data and Information System (ESDIS) Project, along with the 12 EOSDIS Distributed Active Archive Centers (DAACs), has made significant progress in each of these areas over the last decade, and continues to evolve its active archive capabilities. Particular attention is being paid in recent years to ensure that the datasets are "published" in an easily accessible and citable manner through a unified metadata model, a common metadata repository (CMR), a coherent view through the earthdata.gov website, and assignment of Digital Object Identifiers (DOI) with well-designed landing/product information pages.

  9. Proceedings of the First NASA Ada Users' Symposium

    NASA Technical Reports Server (NTRS)

    1988-01-01

    Ada has the potential to be a part of the most significant change in software engineering technology within NASA in the last twenty years. Thus, it is particularly important that all NASA centers be aware of Ada experience and plans at other centers. Ada activity across NASA are covered, with presenters representing five of the nine major NASA centers and the Space Station Freedom Program Office. Projects discussed included - Space Station Freedom Program Office: the implications of Ada on training, reuse, management and the software support environment; Johnson Space Center (JSC): early experience with the use of Ada, software engineering and Ada training and the evaluation of Ada compilers; Marshall Space Flight Center (MSFC): university research with Ada and the application of Ada to Space Station Freedom, the Orbital Maneuvering Vehicle, the Aero-Assist Flight Experiment and the Secure Shuttle Data System; Lewis Research Center (LeRC): the evolution of Ada software to support the Space Station Power Management and Distribution System; Jet Propulsion Laboratory (JPL): the creation of a centralized Ada development laboratory and current applications of Ada including the Real-time Weather Processor for the FAA; and Goddard Space Flight Center (GSFC): experiences with Ada in the Flight Dynamics Division and the Extreme Ultraviolet Explorer (EUVE) project and the implications of GSFC experience for Ada use in NASA. Despite the diversity of the presentations, several common themes emerged from the program: Methodology - NASA experience in general indicates that the effective use of Ada requires modern software engineering methodologies; Training - It is the software engineering principles and methods that surround Ada, rather than Ada itself, which requires the major training effort; Reuse - Due to training and transition costs, the use of Ada may initially actually decrease productivity, as was clearly found at GSFC; and real-time work at LeRC, JPL and GSFC shows

  10. Modernization and Activation of the NASA Ames 11- by 11-Foot Transonic Wind Tunnel

    NASA Technical Reports Server (NTRS)

    Kmak, Frank J.

    2000-01-01

    The Unitary Plan Wind Tunnel (UPWT) was modernized to improve performance, capability, productivity, and reliability. Automation systems were installed in all three UPWT tunnel legs and the Auxiliaries facility. Major improvements were made to the four control rooms, model support systems, main drive motors, and main drive speed control. Pressure vessel repairs and refurbishment to the electrical distribution system were also completed. Significant changes were made to improve test section flow quality in the 11-by 11-Foot Transonic leg. After the completion of the construction phase of the project, acceptance and checkout testing was performed to demonstrate the capabilities of the modernized facility. A pneumatic test of the tunnel circuit was performed to verify the structural integrity of the pressure vessel before wind-on operations. Test section turbulence, flow angularity, and acoustic parameters were measured throughout the tunnel envelope to determine the effects of the tunnel flow quality improvements. The new control system processes were thoroughly checked during wind-off and wind-on operations. Manual subsystem modes and automated supervisory modes of tunnel operation were validated. The aerodynamic and structural performance of both the new composite compressor rotor blades and the old aluminum rotor blades was measured. The entire subsonic and supersonic envelope of the 11-by 11-Foot Transonic leg was defined up to the maximum total pressure.

  11. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Administrator Charles F. Bolden Jr. left on stage, speaks during his first NASA Update as Deputy Administrator Lori Garver looks on at right,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  12. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Administrator Charles F. Bolden Jr., left on stage, speaks during his first NASA Update as Deputy Administrator Lori Garver looks on at right,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  13. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Deputy Administrator Lori Garver makes a point as she speaks during a NASA Update with Administrator Charles F. Bolden Jr.,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  14. Non-Euclidean Space, Movement and Astronomy in Modern Art: Alexander Calder's Mobiles and Ben Nicholson's Reliefs

    NASA Astrophysics Data System (ADS)

    Malloy, Vanja

    2013-09-01

    John Keats once wrote that `there is no such thing as time and space' rather, believing that time and space are mental constructs that are subject to a variety of forms and as diverse as the human mind. In the 1920s through the 1930s, modern physics in many ways supported this idea through the various philosophical writings on the Theory of General Relativity to the masses by scientists such as Arthur Eddington and Albert Einstein. These new concepts of modern physics fundamentally changed our understanding of time and space and had substantial philosophical implications, which were absorbed by modern artists resulting in the 1936 Dimensionist Manifesto. Seeking to internalize the developments of modern science within modern art, this manifesto was widely endorsed by the most prominent figures of the avant-garde such as Marcel Duchamp, Jean Arp, Naum Gabo, Joan Miró, László Moholy-Nagy, Wassily Kandinsky and Alexander Calder. Of particular interest to this manifesto was the new concept of the fourth-dimension, which in many ways revolutionized the arts. Importantly, its interpretation varied widely in the artistic community, ranging from a purely physical four-dimensional space, to a kinetic concept of space in which space and time are linked, to a metaphysical interest in a space that exists beyond the material realm. The impact of modern science and astronomy on avant-garde art is currently a bourgeoning area of research with considerable implications to our rethinking of substantial artistic figures of this era. Through a case study of Alexander Calder's Mobiles and Ben Nicholson's Reliefs, this paper explores how these artworks were informed by an interest in modern science.

  15. Craniofacial morphology in ancient and modern Greeks through 4,000 years.

    PubMed

    Papagrigorakis, Manolis J; Kousoulis, Antonis A; Synodinos, Philippos N

    2014-01-01

    Multiple 20th century studies have speculated on the anthropological similarities of the modern inhabitants of Greece with their ancient predecessors. The present investigation attempts to add to this knowledge by comparing the craniofacial configuration of 141 ancient (dating around 2,000-500 BC) and 240 modern Greek skulls (the largest material among relevant national studies). Skulls were grouped in age at death, sex, era and geographical categories; lateral cephalograms were taken and 53 variables were measured and correlated statistically. The craniofacial measurements and measurements of the basic quadrilateral and cranial polygon were compared in various groups using basic statistical methods, one-way ANOVA and assessment of the correlation matrices. Most of the measurements for both sexes combined followed an akin pattern in ancient and modern Greek skulls. Moreover, sketching and comparing the outline of the skull and upper face, we observed a clock-wise movement. The present study confirms that the morphological pattern of Greek skulls, as it changed during thousands of years, kept some characteristics unchanged, with others undergoing logical modifications. The analysis of our results allows us to believe that the influence upon the craniofacial complex of the various known factors, including genetic or environmental alterations, is apt to alter its form to adapt to new conditions. Even though 4,000 years seems too narrow a span to provoke evolutionary insights using conventional geometric morphometrics, the full presentation of our results makes up a useful atlas of solid data. Interpreted with caution, the craniofacial morphology in modern and ancient Greeks indicates elements of ethnic group continuation within the unavoidable multicultural mixtures.

  16. Lessons Learned in the High-Speed Aerodynamic Research Programs of the NACA/NASA

    NASA Technical Reports Server (NTRS)

    Spearman, M. Leroy

    2004-01-01

    The achievement of flight with manned, powered, heavier-than-air aircraft in 1903 marked the beginning of a new era in the means of transportation. A special advantage for aircraft was in speed. However, when an aircraft penetrates the air at very high speeds, the disturbed air is compressed and there are changes in the density, pressure and temperature of the air. These compressibility effects change the aerodynamic characteristics of an aircraft and introduce problems in drag, stability and control. Many aircraft designed in the post-World War II era were plagued with the effects of compressibility. Accordingly, the study of the aerodynamic behavior of aircraft, spacecraft and missiles at high-speed became a major part of the research activity of the NACA/NASA. The intent of the research was to determine the causes and provide some solutions for the aerodynamic problems resulting from the effects of compressibility. The purpose of this paper is to review some of the high-speed aerodynamic research work conducted at the Langley Research Center from the viewpoint of the author who has been active in much of the effort.

  17. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Administrator Charles F. Bolden Jr. is seen through a television camera monitor during his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator, was joined by Deputy Administrator Lori Garver where they took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  18. NASA Update

    NASA Image and Video Library

    2009-07-20

    NASA Administrator Charles F. Bolden Jr. is seen on a television camera monitor while speaking at his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator, was joined by Deputy Administrator Lori Garver where they took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  19. Diverse data supports the transition of filamentous fungal model organisms into the post-genomics era

    DOE PAGES

    McCluskey, Kevin; Baker, Scott E.

    2017-02-17

    As model organisms filamentous fungi have been important since the beginning of modern biological inquiry and have benefitted from open data since the earliest genetic maps were shared. From early origins in simple Mendelian genetics of mating types, parasexual genetics of colony colour, and the foundational demonstration of the segregation of a nutritional requirement, the contribution of research systems utilising filamentous fungi has spanned the biochemical genetics era, through the molecular genetics era, and now are at the very foundation of diverse omics approaches to research and development. Fungal model organisms have come from most major taxonomic groups although Ascomycetemore » filamentous fungi have seen the most major sustained effort. In addition to the published material about filamentous fungi, shared molecular tools have found application in every area of fungal biology. Likewise, shared data has contributed to the success of model systems. Furthermore, the scale of data supporting research with filamentous fungi has grown by 10 to 12 orders of magnitude. From genetic to molecular maps, expression databases, and finally genome resources, the open and collaborative nature of the research communities has assured that the rising tide of data has lifted all of the research systems together.« less

  20. Diverse data supports the transition of filamentous fungal model organisms into the post-genomics era

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCluskey, Kevin; Baker, Scott E.

    As model organisms filamentous fungi have been important since the beginning of modern biological inquiry and have benefitted from open data since the earliest genetic maps were shared. From early origins in simple Mendelian genetics of mating types, parasexual genetics of colony colour, and the foundational demonstration of the segregation of a nutritional requirement, the contribution of research systems utilising filamentous fungi has spanned the biochemical genetics era, through the molecular genetics era, and now are at the very foundation of diverse omics approaches to research and development. Fungal model organisms have come from most major taxonomic groups although Ascomycetemore » filamentous fungi have seen the most major sustained effort. In addition to the published material about filamentous fungi, shared molecular tools have found application in every area of fungal biology. Likewise, shared data has contributed to the success of model systems. Furthermore, the scale of data supporting research with filamentous fungi has grown by 10 to 12 orders of magnitude. From genetic to molecular maps, expression databases, and finally genome resources, the open and collaborative nature of the research communities has assured that the rising tide of data has lifted all of the research systems together.« less

  1. Nutrigenomics in the modern era.

    PubMed

    Mathers, John C

    2017-08-01

    The concept that interactions between nutrition and genetics determine phenotype was established by Garrod at the beginning of the 20th century through his ground-breaking work on inborn errors of metabolism. A century later, the science and technologies involved in sequencing of the human genome stimulated development of the scientific discipline which we now recognise as nutritional genomics (nutrigenomics). Much of the early hype around possible applications of this new science was unhelpful and raised expectations, which have not been realised as quickly as some would have hoped. However, major advances have been made in quantifying the contribution of genetic variation to a wide range of phenotypes and it is now clear that for nutrition-related phenotypes, such as obesity and common complex diseases, the genetic contribution made by SNP alone is often modest. There is much scope for innovative research to understand the roles of less well explored types of genomic structural variation, e.g. copy number variants, and of interactions between genotype and dietary factors, in phenotype determination. New tools and models, including stem cell-based approaches and genome editing, have huge potential to transform mechanistic nutrition research. Finally, the application of nutrigenomics research offers substantial potential to improve public health e.g. through the use of metabolomics approaches to identify novel biomarkers of food intake, which will lead to more objective and robust measures of dietary exposure. In addition, nutrigenomics may have applications in the development of personalised nutrition interventions, which may facilitate larger, more appropriate and sustained changes in eating (and other lifestyle) behaviours and help to reduce health inequalities.

  2. The Progressive Era.

    PubMed

    Chambers, David W

    2005-01-01

    The American College of Dentists was founded in 1920 for the purpose of encouraging young dentists to continue study and to apply science to their practices. This ideal emerged in the Progressive Era, which lasted roughly from 1895 to 1920. The animating spirit of this period was that the human condition could be improved and that the way to achieve this was through science and the use of experts working together. The Progressive Era saw inventions, such as automobiles and airplanes, telephone and radio, that required mass production and brought people together. It also spawned many political and legislative innovations that we now take for granted. Among these are the Food and Drug Administration, the Department of Commerce, and the Federal Trade Commission. Workers' compensation and other social protections were introduced, as were city commissions; the income tax; women's suffrage; and initiative, referendum, and recall. Medicine, for the first time, became an effective way to treat disease as it developed a scientific foundation.

  3. 38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2012-07-01 2012-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

  4. 38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2013-07-01 2013-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

  5. 38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2011-07-01 2011-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

  6. 38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

  7. 38 CFR 21.5020 - Post-Vietnam era veterans' educational assistance.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2014-07-01 2014-07-01 false Post-Vietnam era veterans... AFFAIRS (CONTINUED) VOCATIONAL REHABILITATION AND EDUCATION Post-Vietnam Era Veterans' Educational Assistance Under 38 U.S.C. Chapter 32 General § 21.5020 Post-Vietnam era veterans' educational assistance...

  8. Modern Gemini-Approach to Technology Development for Human Space Exploration

    NASA Technical Reports Server (NTRS)

    White, Harold

    2010-01-01

    In NASA's plan to put men on the moon, there were three sequential programs: Mercury, Gemini, and Apollo. The Gemini program was used to develop and integrate the technologies that would be necessary for the Apollo program to successfully put men on the moon. We would like to present an analogous modern approach that leverages legacy ISS hardware designs, and integrates developing new technologies into a flexible architecture This new architecture is scalable, sustainable, and can be used to establish human exploration infrastructure beyond low earth orbit and into deep space.

  9. ERA: Adverse Consequences

    ERIC Educational Resources Information Center

    Martin, Brian

    2011-01-01

    Excellence in Research for Australia has a number of limitations: inputs are counted as outputs, time is wasted, disciplinary research is favoured and public engagement is discouraged. Most importantly, by focusing on measurement and emphasising competition, ERA may actually undermine the cooperation and intrinsic motivation that underpin research…

  10. NASA Releases 'NASA App HD' for iPad

    NASA Image and Video Library

    2012-07-06

    The NASA App HD invites you to discover a wealth of NASA information right on your iPad. The application collects, customizes and delivers an extensive selection of dynamically updated mission information, images, videos and Twitter feeds from various online NASA sources in a convenient mobile package. Come explore with NASA, now on your iPad. 2012 Updated Version - HD Resolution and new features. Original version published on Sept. 1, 2010.

  11. 14 CFR 1240.105 - Special procedures-NASA and NASA contractor employees.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Special procedures-NASA and NASA contractor...—NASA and NASA contractor employees. (a) A NASA Headquarters office, a NASA field installation, or a NASA contractor may submit to the Board an application for an award identifying the originator(s) of...

  12. 14 CFR 1240.105 - Special procedures-NASA and NASA contractor employees.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Special procedures-NASA and NASA contractor...—NASA and NASA contractor employees. (a) A NASA Headquarters office, a NASA field installation, or a NASA contractor may submit to the Board an application for an award identifying the originator(s) of...

  13. 14 CFR 1240.105 - Special procedures-NASA and NASA contractor employees.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Special procedures-NASA and NASA contractor...—NASA and NASA contractor employees. (a) A NASA Headquarters office, a NASA field installation, or a NASA contractor may submit to the Board an application for an award identifying the originator(s) of...

  14. Evaluation of ERA-Interim precipitation data in complex terrain

    NASA Astrophysics Data System (ADS)

    Gao, Lu; Bernhardt, Matthias; Schulz, Karsten

    2013-04-01

    Precipitation controls a large variety of environmental processes, which is an essential input parameter for land surface models e.g. in hydrology, ecology and climatology. However, rain gauge networks provides the necessary information, are commonly sparse in complex terrains, especially in high mountainous regions. Reanalysis products (e.g. ERA-40 and NCEP-NCAR) as surrogate data are increasing applied in the past years. Although they are improving forward, previous studies showed that these products should be objectively evaluated due to their various uncertainties. In this study, we evaluated the precipitation data from ERA-Interim, which is a latest reanalysis product developed by ECMWF. ERA-Interim daily total precipitation are compared with high resolution gridded observation dataset (E-OBS) at 0.25°×0.25° grids for the period 1979-2010 over central Alps (45.5-48°N, 6.25-11.5°E). Wet or dry day is defined using different threshold values (0.5mm, 1mm, 5mm, 10mm and 20mm). The correspondence ratio (CR) is applied for frequency comparison, which is the ratio of days when precipitation occurs in both ERA-Interim and E-OBS dataset. The result shows that ERA-Interim captures precipitation occurrence very well with a range of CR from 0.80 to 0.97 for 0.5mm to 20mm thresholds. However, the bias of intensity increases with rising thresholds. Mean absolute error (MAE) varies between 4.5 mm day-1 and 9.5 mm day-1 in wet days for whole area. In term of mean annual cycle, ERA-Interim almost has the same standard deviation of the interannual variability of daily precipitation with E-OBS, 1.0 mm day-1. Significant wet biases happened in ERA-Interim throughout warm season (May to August) and dry biases in cold season (November to February). The spatial distribution of mean annual daily precipitation shows that ERA-Interim significant underestimates precipitation intensity in high mountains and northern flank of Alpine chain from November to March while pronounced

  15. NASA Social

    NASA Image and Video Library

    2012-05-19

    A NASA Social follower holds up a mobile device as NASA Administrator Charles Bolden, left, and Kennedy Space Center director Robert Cabana appear at the NASA Social event, Friday morning, May 19, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

  16. The Navajo Learning Network and the NASA Life Sciences/AFOSR Infrastructure Development Project

    NASA Technical Reports Server (NTRS)

    1999-01-01

    The NSF-funded Navajo Learning Network project, with help from NASA Life Sciences and AFOSR, enabled Dine College to take a giant leap forward technologically - in a way that could never had been possible had these projects been managed separately. The combination of these and other efforts created a network of over 500 computers located at ten sites across the Navajo reservation. Additionally, the college was able to install a modern telephone system which shares network data, and purchase a new higher education management system. The NASA Life Sciences funds further allowed the college library system to go online and become available to the entire campus community. NSF, NASA and AFOSR are committed to improving minority access to higher education opportunities and promoting faculty development and undergraduate research through infrastructure support and development. This project has begun to address critical inequalities in access to science, mathematics, engineering and technology for Navajo students and educators. As a result, Navajo K-12 education has been bolstered and Dine College will therefore better prepare students to transfer successfully to four-year institutions. Due to the integration of the NSF and NASA/AFOSR components of the project, a unified project report is appropriate.

  17. Molecular Tumor Boards: Ethical Issues in the New Era of Data Medicine.

    PubMed

    Stoeklé, Henri-Corto; Mamzer-Bruneel, Marie-France; Frouart, Charles-Henry; Le Tourneau, Christophe; Laurent-Puig, Pierre; Vogt, Guillaume; Hervé, Christian

    2018-02-01

    The practice and development of modern medicine requires large amounts of data, particularly in the domain of cancer. The future of personalized medicine lies neither with "genomic medicine" nor with "precision medicine", but with "data medicine" (DM) (big data, data mining). The establishment of this DM has required far-reaching changes, to establish four essential elements connecting patients and doctors: biobanks, databases, bioinformatic platforms and genomic platforms. The "transformation" of scientific research areas, such as genetics, bioinformatics and biostatistics, into clinical specialties has generated a new vision of care. Molecular tumor boards (MTB) are one response to these changes and are now providing better access to next-generation sequencing (NGS) and new cancer treatments to patients with inoperable or metastatic cancers, and those for whom the usual treatment has failed. However, MTB face a crucial ethical challenge: maintaining and improving the trust of patients, clinicians, researchers and industry in academic medical centers supported by private or public funding rather than providing genetic data directly to private companies. We believe that, in this era of DM, appropriate modern digital communication networks will be required to maintain this trust and to improve the organization and effectiveness of the system. There is, therefore, a need to reconsider the form and content of informed consent (IC) documents at all academic medical centers and to introduce dynamic and electronic informed consent (e-IC).

  18. The Impact of Apollo-Era Microbiology on Human Space Flight

    NASA Technical Reports Server (NTRS)

    Elliott, T. F; Castro, V. A.; Bruce, R. J.; Pierson, D. L.

    2014-01-01

    The microbiota of crewmembers and the spacecraft environment contributes significant risk to crew health during space flight missions. NASA reduces microbial risk with various mitigation methods that originated during the Apollo Program and continued to evolve through subsequent programs: Skylab, Shuttle, and International Space Station (ISS). A quarantine of the crew and lunar surface samples, within the Lunar Receiving Laboratory following return from the Moon, was used to prevent contamination with unknown extraterrestrial organisms. The quarantine durations for the crew and lunar samples were 21 days and 50 days, respectively. A series of infections among Apollo crewmembers resulted in a quarantine before launch to limit exposure to infectious organisms. This Health Stabilization Program isolated the crew for 21 days before flight and was effective in reducing crew illness. After the program developed water recovery hardware for Apollo spacecraft, the 1967 National Academy of Science Space Science Board recommended the monitoring of potable water. NASA implemented acceptability limits of 10 colony forming units (CFU) per mL and the absence of viable E. coli, anaerobes, yeasts, and molds in three separate 150 mL aliquots. Microbiological investigations of the crew and spacecraft environment were conducted during the Apollo program, including the Apollo-Soyuz Test Project and Skylab. Subsequent space programs implemented microbial screening of the crew for pathogens and acceptability limits on spacecraft surfaces and air. Microbiology risk mitigation methods have evolved since the Apollo program. NASA cancelled the quarantine of the crew after return from the lunar surface, reduced the duration of the Health Stabilization Program; and implemented acceptability limits for spacecraft surfaces and air. While microbial risks were not a main focus of the early Mercury and Gemini programs, the extended duration of Apollo flights resulted in the increased scrutiny of

  19. Assessment of the NASA Astrobiology Institute

    NASA Technical Reports Server (NTRS)

    2008-01-01

    Astrobiology is a scientific discipline devoted to the study of life in the universe--its origins, evolution, distribution, and future. It brings together the physical and biological sciences to address some of the most fundamental questions of the natural world: How do living systems emerge? How do habitable worlds form and how do they evolve? Does life exist on worlds other than Earth? As an endeavor of tremendous breadth and depth, astrobiology requires interdisciplinary investigation in order to be fully appreciated and examined. As part of a concerted effort to undertake such a challenge, the NASA Astrobiology Institute (NAI) was established in 1998 as an innovative way to develop the field of astrobiology and provide a scientific framework for flight missions. Now that the NAI has been in existence for almost a decade, the time is ripe to assess its achievements. At the request of NASA's Associate Administrator for the Science Mission Directorate (SMD), the Committee on the Review of the NASA Astrobiology Institute undertook the assignment to determine the progress made by the NAI in developing the field of astrobiology. It must be emphasized that the purpose of this study was not to undertake a review of the scientific accomplishments of NASA's Astrobiology program, in general, or of the NAI, in particular. Rather, the objective of the study is to evaluate the success of the NAI in achieving its stated goals of: 1. Conducting, supporting, and catalyzing collaborative interdisciplinary research; 2. Training the next generation of astrobiology researchers; 3. Providing scientific and technical leadership on astrobiology investigations for current and future space missions; 4. Exploring new approaches, using modern information technology, to conduct interdisciplinary and collaborative research among widely distributed investigators; and 5. Supporting outreach by providing scientific content for use in K-12 education programs, teaching undergraduate classes, and

  20. Cosmology with a stiff matter era

    NASA Astrophysics Data System (ADS)

    Chavanis, Pierre-Henri

    2015-11-01

    We consider the possibility that the Universe is made of a dark fluid described by a quadratic equation of state P =K ρ2 , where ρ is the rest-mass density and K is a constant. The energy density ɛ =ρ c2+K ρ2 is the sum of two terms: a rest-mass term ρ c2 that mimics "dark matter" (P =0 ) and an internal energy term u =K ρ2=P that mimics a "stiff fluid" (P =ɛ ) in which the speed of sound is equal to the speed of light. In the early universe, the internal energy dominates and the dark fluid behaves as a stiff fluid (P ˜ɛ , ɛ ∝a-6). In the late universe, the rest-mass energy dominates and the dark fluid behaves as pressureless dark matter (P ≃0 , ɛ ∝a-3). We provide a simple analytical solution of the Friedmann equations for a universe undergoing a stiff matter era, a dark matter era, and a dark energy era due to the cosmological constant. This analytical solution generalizes the Einstein-de Sitter solution describing the dark matter era, and the Λ CDM model describing the dark matter era and the dark energy era. Historically, the possibility of a primordial stiff matter era first appeared in the cosmological model of Zel'dovich where the primordial universe is assumed to be made of a cold gas of baryons. A primordial stiff matter era also occurs in recent cosmological models where dark matter is made of relativistic self-gravitating Bose-Einstein condensates (BECs). When the internal energy of the dark fluid mimicking stiff matter is positive, the primordial universe is singular like in the standard big bang theory. It expands from an initial state with a vanishing scale factor and an infinite density. We consider the possibility that the internal energy of the dark fluid is negative (while, of course, its total energy density is positive), so that it mimics anti-stiff matter. This happens, for example, when the BECs have an attractive self-interaction with a negative scattering length. In that case, the primordial universe is nonsingular and

  1. NASA Update

    NASA Image and Video Library

    2009-07-20

    Alan Ladwig, Senior Advisor to the NASA Administrator, introduces Administrator Charles F. Bolden Jr. and Deputy Administrator Lori Garver at a NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, the agency's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

  2. NASA Social

    NASA Image and Video Library

    2011-05-18

    Ed Mango, of the NASA Commercial Crew Office, speaks during a NASA Social, Friday, May 18, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

  3. Historical time to disease progression and progression-free survival in patients with recurrent/refractory neuroblastoma treated in the modern era on Children's Oncology Group early-phase trials.

    PubMed

    London, Wendy B; Bagatell, Rochelle; Weigel, Brenda J; Fox, Elizabeth; Guo, Dongjing; Van Ryn, Collin; Naranjo, Arlene; Park, Julie R

    2017-12-15

    Early-phase trials in patients with recurrent neuroblastoma historically used an objective "response" of measureable disease (Response Evaluation Criteria In Solid Tumors [RECIST], without bone/bone marrow assessment) to select agents for further study. Historical cohorts may be small and potentially biased; to the authors' knowledge, disease recurrence studies from international registries are outdated. Using a large recent cohort of patients with recurrent/refractory neuroblastoma from Children's Oncology Group (COG) modern-era early-phase trials, the authors determined outcome and quantified parameters for designing future studies. The first early-phase COG trial enrollment (sequential) of 383 distinct patients with recurrent/refractory neuroblastoma on 23 phase 1, 3 phase 1/2, and 9 phase 2 trials (August 2002 to January 2014) was analyzed for progression-free survival (PFS), overall survival (OS), and time to disease progression (TTP). Planned frontline therapy for patients with high-risk neuroblastoma included hematopoietic stem cell transplantation (approximately two-thirds of patients underwent ≥1 hematopoietic stem cell transplantation); 13.2% of patients received dinutuximab. From the time of the patient's first early-phase trial enrollment (383 patients), the 1-year and 4-year PFS rates ( ± standard error) were 21% ± 2% and 6% ± 1%, respectively, whereas the 1-year and 4-year OS rates were 57% ± 3% and 20% ± 2%, respectively. The median TTP was 58 days (interquartile range, 31-183 days [350 patients]); the median follow-up was 25.3 months (33 patients were found to be without disease recurrence/progression). The median time from diagnosis to first disease recurrence/progression was 18.7 months (range, 1.4-64.8 months) (176 patients). MYCN amplification and 11q loss of heterozygosity were prognostic of worse PFS and OS (P = .003 and P<.0001, respectively, and P = .02 and P = .03, respectively) after early-phase trial

  4. Selling to NASA

    NASA Technical Reports Server (NTRS)

    1990-01-01

    This handbook is designed to promote a better understanding of NASA's interests and the process of doing business with NASA. The document is divided into the following sections: (1) this is NASA; (2) the procurement process; (3) marketing your capabilities; (4) special assistance programs; (5) NASA field installations; (6) sources of additional help; (7) listing of NASA small/minority business personnel; and (8) NASA organization chart.

  5. NASA/Navy Benchmarking Exchange (NNBE). Volume 1. Interim Report. Navy Submarine Program Safety Assurance

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The NASA/Navy Benchmarking Exchange (NNBE) was undertaken to identify practices and procedures and to share lessons learned in the Navy's submarine and NASA's human space flight programs. The NNBE focus is on safety and mission assurance policies, processes, accountability, and control measures. This report is an interim summary of activity conducted through October 2002, and it coincides with completion of the first phase of a two-phase fact-finding effort.In August 2002, a team was formed, co-chaired by senior representatives from the NASA Office of Safety and Mission Assurance and the NAVSEA 92Q Submarine Safety and Quality Assurance Division. The team closely examined the two elements of submarine safety (SUBSAFE) certification: (1) new design/construction (initial certification) and (2) maintenance and modernization (sustaining certification), with a focus on: (1) Management and Organization, (2) Safety Requirements (technical and administrative), (3) Implementation Processes, (4) Compliance Verification Processes, and (5) Certification Processes.

  6. The modern CIO: forging a new role in the managed care era.

    PubMed

    Griffin, J

    1997-05-01

    The advent of managed care has helped forge new roles for healthcare professionals. Competitive pressures, the profile of the member community, and provider network design drive healthcare delivery via the managed care model. Careful analysis and design of the managed care model charts the success or failure of the health care delivery system--usually an integrated delivery system (IDS). Therefore, those healthcare organizations that have chosen to get on the managed care bandwagon must re-invent themselves, both culturally and technologically. The chief information officer (CIO) leads this technological revolution. To work effectively, the technological infrastructure of the IDS must be closely in line with enterprise goals and objectives. In the managed care environment the old information system (IS) approach of supporting the operational needs of individual departments simply will not work. The CIO's new role will be to master the concept of managed care to ensure that enterprise-wide needs for operational, clinical, and financial information are met, and that IS and enterprise goals are aligned. CIOs who have an intuitive grasp of the managed care environment--although their numbers are growing as managed care mushrooms--make up a minority group. They are a special breed with clearly definable qualities such as business savvy and an affinity for big-picture thinking. To an IDS, a CIO with these qualities is a rare gem indeed. This article introduces Don Winschel, the associate administrator and CIO of Johnson City Medical Center (Johnson City, TN) as an example of one such modern CIO.

  7. A New Era for Research Education in Australia?

    ERIC Educational Resources Information Center

    Marsh, Helene; Smith, Bradley; King, Max; Evans, Terry

    2012-01-01

    Use of the Australian research assessment exercise, Excellence in Research for Australia (ERA) to influence the policy and practice of research education in Australia will undoubtedly have many consequences, some of them unintended and potentially deleterious. ERA is a retrospective measure of research quality; research education is prospective.…

  8. Modern mammal origins: evolutionary grades in the Early Cretaceous of North America.

    PubMed

    Jacobs, L L; Winkler, D A; Murry, P A

    1989-07-01

    Major groups of modern mammals have their origins in the Mesozoic Era, yet the mammalian fossil record is generally poor for that time interval. Fundamental morphological changes that led to modern mammals are often represented by small samples of isolated teeth. Fortunately, functional wear facets on teeth allow prediction of the morphology of occluding teeth that may be unrepresented by fossils. A major step in mammalian evolution occurred in the Early Cretaceous with the evolution of tribosphenic molars, which characterize marsupials and placentals, the two most abundant and diverse extant groups of mammals. A tooth from the Early Cretaceous (110 million years before present) of Texas tests previous predictions (based on lower molars) of the morphology of upper molars in early tribosphenic dentitions. The lingual cusp (protocone) is primitively without shear facets, as expected, but the cheek side of the tooth is derived (advanced) in having distinctive cusps along the margin. The tooth, although distressingly inadequate to define many features of the organism, demonstrates unexpected morphological diversity at a strategic stage of mammalian evolution and falsifies previous claims of the earliest occurrence of true marsupials.

  9. Modern mammal origins: evolutionary grades in the Early Cretaceous of North America.

    PubMed Central

    Jacobs, L L; Winkler, D A; Murry, P A

    1989-01-01

    Major groups of modern mammals have their origins in the Mesozoic Era, yet the mammalian fossil record is generally poor for that time interval. Fundamental morphological changes that led to modern mammals are often represented by small samples of isolated teeth. Fortunately, functional wear facets on teeth allow prediction of the morphology of occluding teeth that may be unrepresented by fossils. A major step in mammalian evolution occurred in the Early Cretaceous with the evolution of tribosphenic molars, which characterize marsupials and placentals, the two most abundant and diverse extant groups of mammals. A tooth from the Early Cretaceous (110 million years before present) of Texas tests previous predictions (based on lower molars) of the morphology of upper molars in early tribosphenic dentitions. The lingual cusp (protocone) is primitively without shear facets, as expected, but the cheek side of the tooth is derived (advanced) in having distinctive cusps along the margin. The tooth, although distressingly inadequate to define many features of the organism, demonstrates unexpected morphological diversity at a strategic stage of mammalian evolution and falsifies previous claims of the earliest occurrence of true marsupials. Images PMID:2740336

  10. NASA Social

    NASA Image and Video Library

    2012-12-04

    NASA astronaut Joe Acaba answers questions at a NASA Social at NASA Headquarters on Tuesday, Dec. 4, 2012 in Washington. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  11. Turbofan Noise Studied in Unique Model Research Program in NASA Glenn's 9- by 15-Foot Low-Speed Wind Tunnel

    NASA Technical Reports Server (NTRS)

    Hughes, Christopher E.

    2001-01-01

    A comprehensive aeroacoustic research program called the Source Diagnostic Test was recently concluded in NASA Glenn Research Center's 9- by 15-Foot Low Speed Wind Tunnel. The testing involved representatives from Glenn, NASA Langley Research Center, GE Aircraft Engines, and the Boeing Company. The technical objectives of this research were to identify the different source mechanisms of noise in a modern, high-bypass turbofan aircraft engine through scale-model testing and to make detailed acoustic and aerodynamic measurements to more fully understand the physics of how turbofan noise is generated.

  12. NASA's Space Launch Transitions: From Design to Production

    NASA Technical Reports Server (NTRS)

    Askins, Bruce; Robinson, Kimberly

    2016-01-01

    NASA's Space Launch System (SLS) successfully completed its Critical Design Review (CDR) in 2015, a major milestone on the journey to an unprecedented era of exploration for humanity. CDR formally marked the program's transition from design to production phase just four years after the program's inception and the first such milestone for a human launch vehicle in 40 years. While challenges typical of a complex development program lie ahead, CDR evaluators concluded that the design is technically and programmatically sound and ready to press forward to Design Certification Review (DCR) and readiness for launch of Exploration Mission 1 (EM-1) in the 2018 timeframe. SLS is prudently based on existing propulsion systems, infrastructure and knowledge with a clear, evolutionary path as required by mission needs. In its initial configuration, designated Block I, SLS will a minimum of 70 metric tons (t) of payload to low Earth orbit (LEO). It can evolve to a 130 t payload capacity by upgrading its engines, boosters, and upper stage, dramatically increasing the mass and volume of human and robotic exploration while decreasing mission risk, increasing safety, and simplifying ground and mission operations. CDR was the central programmatic accomplishment among many technical accomplishments that will be described in this paper. The government/industry SLS team successfully test fired a flight-like five-segment solid rocket motor, as well as seven hotfire development tests of the RS-25 core stage engine. The majority of the major test article and flight barrels, rings, and domes for the core stage liquid oxygen, liquid hydrogen, engine section, intertank, and forward skirt were manufactured at NASA's Michoud Assembly Facility. Renovations to the B-2 test stand for stage green run testing were completed at NASA Stennis Space Center. Core stage test stands are rising at NASA Marshall Space Flight Center. The modified Pegasus barge for core stage transportation from manufacturing

  13. Molecular clocks indicate turnover and diversification of modern coleoid cephalopods during the Mesozoic Marine Revolution

    PubMed Central

    Fuchs, Dirk; Winkelmann, Inger E.; Gilbert, M. Thomas P.; Pankey, M. Sabrina; Ribeiro, Ângela M.; Kocot, Kevin M.; Halanych, Kenneth M.; Oakley, Todd H.; da Fonseca, Rute R.

    2017-01-01

    Coleoid cephalopod molluscs comprise squid, cuttlefish and octopuses, and represent nearly the entire diversity of modern cephalopods. Sophisticated adaptations such as the use of colour for camouflage and communication, jet propulsion and the ink sac highlight the unique nature of the group. Despite these striking adaptations, there are clear parallels in ecology between coleoids and bony fishes. The coleoid fossil record is limited, however, hindering confident analysis of the tempo and pattern of their evolution. Here we use a molecular dataset (180 genes, approx. 36 000 amino acids) of 26 cephalopod species to explore the phylogeny and timing of cephalopod evolution. We show that crown cephalopods diverged in the Silurian–Devonian, while crown coleoids had origins in the latest Palaeozoic. While the deep-sea vampire squid and dumbo octopuses have ancient origins extending to the Early Mesozoic Era, 242 ± 38 Ma, incirrate octopuses and the decabrachian coleoids (10-armed squid) diversified in the Jurassic Period. These divergence estimates highlight the modern diversity of coleoid cephalopods emerging in the Mesozoic Marine Revolution, a period that also witnessed the radiation of most ray-finned fish groups in addition to several other marine vertebrates. This suggests that that the origin of modern cephalopod biodiversity was contingent on ecological competition with marine vertebrates. PMID:28250188

  14. Destructive Thomas Fire Continues Its Advance in New NASA Satellite Image

    NASA Image and Video Library

    2017-12-11

    The Thomas fire, west of Los Angeles, continues to advance to the west and north and is threatening a number of coastal communities, including Santa Barbara. It is now the fifth largest wildfire in modern California history. According to CAL FIRE, as of midday Dec. 11, the fire had consumed more than 230,000 acres and was 15 percent contained. The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) instrument on NASA's Terra satellite captured this image on Dec. 10. The image depicts vegetation in red, smoke in light brown, burned areas in dark grey, and active fires in yellow, as detected by the thermal infrared bands. The image covers an area of 14.3 by 19.6 miles (23 by 31.5 kilometers), and is located at 34.5 degrees north, 119.4 degrees west. https://photojournal.jpl.nasa.gov/catalog/PIA22122

  15. NASA Future Forum

    NASA Image and Video Library

    2011-08-11

    Dr. Laurie Leshin, NASA Deputy Associate Administrator Exploration Systems Mission Directortorate, second from right, speaks as Dr. Waleed Abdalati, NASA Chief Scientist, right, Dr. Robert Braun, NASA Chief Technologist, and Leland Melvin, Assoicate Administrator for NASA Education, far left, at the NASA Future Forum held at the Riggs Alumni Center on the campus of the University of Maryland, Thursday, Aug. 11, 2011 in College Park, Md. Photo Credit: (NASA/Paul E. Alers)

  16. NASA Social

    NASA Image and Video Library

    2012-05-19

    NASA Administrator Charles Bolden, left, and Kennedy Space Center director Robert Cabana appear at the NASA Social event, Friday morning, May 19, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

  17. NASA Social

    NASA Image and Video Library

    2012-12-04

    NASA astronaut Joe Acaba speaks at a behind-the-scenes NASA Social at NASA Headquarters on Tuesday, Dec. 4, 2012 in Washington. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  18. NASA Social

    NASA Image and Video Library

    2012-12-04

    A NASA Social participant tweets during as astronaut Joe Acaba answers questions from the audience at NASA Headquaters, Tuesday, Dec. 4, 2012 in Washington. NASA astronaut Acaba launched to the ISS on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  19. NASA Social

    NASA Image and Video Library

    2012-12-04

    NASA astronaut Joe Acaba answers questions at a behind-the-scenes NASA Social at NASA Headquarters on Tuesday, Dec. 4, 2012 in Washington. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  20. NASA Social

    NASA Image and Video Library

    2012-12-04

    NASA astronaut Joe Acaba, center, greets participants at a behind-the-scenes NASA Social in Washington, Tuesday, Dec. 4, 2012 at NASA Headquarters. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  1. C3: A Command-line Catalogue Cross-matching tool for modern astrophysical survey data

    NASA Astrophysics Data System (ADS)

    Riccio, Giuseppe; Brescia, Massimo; Cavuoti, Stefano; Mercurio, Amata; di Giorgio, Anna Maria; Molinari, Sergio

    2017-06-01

    In the current data-driven science era, it is needed that data analysis techniques has to quickly evolve to face with data whose dimensions has increased up to the Petabyte scale. In particular, being modern astrophysics based on multi-wavelength data organized into large catalogues, it is crucial that the astronomical catalog cross-matching methods, strongly dependant from the catalogues size, must ensure efficiency, reliability and scalability. Furthermore, multi-band data are archived and reduced in different ways, so that the resulting catalogues may differ each other in formats, resolution, data structure, etc, thus requiring the highest generality of cross-matching features. We present C 3 (Command-line Catalogue Cross-match), a multi-platform application designed to efficiently cross-match massive catalogues from modern surveys. Conceived as a stand-alone command-line process or a module within generic data reduction/analysis pipeline, it provides the maximum flexibility, in terms of portability, configuration, coordinates and cross-matching types, ensuring high performance capabilities by using a multi-core parallel processing paradigm and a sky partitioning algorithm.

  2. Overview of Icing Research at NASA Glenn

    NASA Technical Reports Server (NTRS)

    Kreeger, Richard E.

    2013-01-01

    The aviation industry continues to deal with icing-related incidents and accidents on a regular basis. Air traffic continues to increase, placing more aircraft in adverse icing conditions more frequently and for longer periods. Icing conditions once considered rare or of little consequence, such as super-cooled large droplet icing or high altitude ice crystals, have emerged as major concerns for modern aviation. Because of this, there is a need to better understand the atmospheric environment, the fundamental mechanisms and characteristics of ice growth, and the aerodynamic effects due to icing, as well as how best to protect these aircraft. The icing branch at NASA Glenn continues to develop icing simulation methods and engineering tools to address current aviation safety issues in airframe, engine and rotorcraft icing.

  3. Progressive-Era Resources on the World Wide Web.

    ERIC Educational Resources Information Center

    Howenstein, Amanda

    1999-01-01

    Provides a list of Progressive-era websites with the address and a detailed description of each of the websites. Includes topics such as the womens suffrage movement, the Triangle Shirtwaist Factory fire, the Prohibition, labor-management conflicts, the Hull House, the Chicago fire, Emma Goldman, Progressive-era entertainment, and the Worlds Fair.…

  4. NASA's EOSDIS: options for data providers

    NASA Astrophysics Data System (ADS)

    Khalsa, Siri J.; Ujhazy, John E.

    1995-12-01

    EOSDIS, the data and information system being developed by NASA to support interdisciplinary earth science research into the 21st century, will do more than manage and distribute data from EOS-era satellites. It will also promote the exchange of data, tools, and research results across disciplinary, agency, and national boundaries. This paper describes the options that data providers will have for interacting with the EOSDIS Core System (ECS), the infrastructure of EOSDIS. The options include: using the ECS advertising service to announce the availability of data at the provider's site; submitting a candidate data set to one of the Distributed Active Archive Centers (DAACs); establishing a data server that will make the data accessible via ECS and establishing Local Information Manager (LIM) which would make the data available for multi-site searches. One additional option is through custom gateway interfaces which would provide access to existing data archives. The gateway, data server, and LIM options require the implementation of ECS code at the provider site to insure proper protocols. The advertisement and ingest options require no part of ECS design to reside at the provider site.

  5. NASA Future Forum

    NASA Image and Video Library

    2011-08-11

    Dr. Robert Braun, NASA Chief Technologist, second from left, makes a point, as panelists Leland Melvin, Assoicate Administrator for NASA Education, left, Dr. Laurie Leshin, NASA Deputy Associate Administrator Exploration Systems Mission Directortorate, and Dr. Waleed Abdalati, NASA Chief Scientist, right, look on during a panel discussion at the NASA Future Forum held at the Riggs Alumni Center on the campus of the University of Maryland, Thursday, Aug. 11, 2011 in College Park, Md. Photo Credit: (NASA/Paul E. Alers)

  6. Results of low power deicer tests on a swept inlet component in the NASA Lewis icing research tunnel

    NASA Technical Reports Server (NTRS)

    Bond, Thomas H.; Shin, Jaiwon

    1993-01-01

    Tests were conducted under a USAF/NASA Low Power Deicer program on two expulsive technologies to examine system performance on hardware representative of a modern aircraft part. The BF Goodrich Electro-Expulsive Deicing System and Pneumatic Impulse Ice Protection System were installed on a swept, compound curve, engine inlet component with varying leading edge radius, and tested through a range of icing and system operating conditions in the NASA Lewis Icing Research Tunnel. A description of the experimental procedure and results, including residual ice thickness, shed ice particle size, and changes in system energy/pressure characteristics are presented.

  7. Results of Low Power Deicer tests on a swept inlet component in the NASA Lewis Icing Research Tunnel

    NASA Technical Reports Server (NTRS)

    Bond, Thomas H.; Shin, Jaiwon

    1993-01-01

    Tests were conducted under a USAF/NASA Low Power Deicer program on two expulsive technologies to examine system performance on hardware representative of a modern aircraft part. The BF Goodrich Electro-Expulsive Deicing System and Pneumatic Impulse Ice Protection system were installed on a swept, compound curve, engine inlet component with varying leading edge radius, and tested through a range of icing and system operating conditions in the NASA Lewis Icing Research Tunnel. A description of the experimental procedure and results, including residual ice thickness, shed ice particle size, and changes in system energy/pressure characteristics are presented.

  8. Predesign study for a modern 4-bladed rotor for the NASA rotor systems research aircraft

    NASA Technical Reports Server (NTRS)

    Bishop, H. E.; Burkam, J. E.; Heminway, R. C.; Keys, C. N.; Smith, K. E.; Smith, J. H.; Staley, J. A.

    1981-01-01

    Trade-off study results and the rationale for the final selection of an existing modern four-bladed rotor system that can be adapted for installation on the Rotor Systems Research Aircraft (RSRA) are reported. The results of the detailed integration studies, parameter change studies, and instrumentation studies and the recommended plan for development and qualification of the rotor system is also given. Its parameter variants, integration on the RSRA, and support of ground and flight test programs are also discussed.

  9. High Energy Astrophysics and Cosmology from Space: NASA's Physics of the Cosmos Program

    NASA Astrophysics Data System (ADS)

    Hornschemeier, Ann

    2016-03-01

    We summarize currently-funded NASA activities in high energy astrophysics and cosmology, embodied in the NASA Physics of the Cosmos program, including updates on technology development and mission studies. The portfolio includes development of a space mission for measuring gravitational waves from merging supermassive black holes, currently envisioned as a collaboration with the European Space Agency (ESA) on its L3 mission and development of an X-ray observatory that will measure X-ray emission from the final stages of accretion onto black holes, currently envisioned as a NASA collaboration on ESA's Athena observatory. The portfolio also includes the study of cosmic rays and gamma ray photons resulting from a range of processes, of the physical process of inflation associated with the birth of the universe and of the nature of the dark energy that dominates the mass-energy of the modern universe. The program is supported by an analysis group called the PhysPAG that serves as a forum for community input and analysis and the talk will include a description of activities of this group.

  10. NASA Social

    NASA Image and Video Library

    2012-12-04

    A participant at a NASA Social in Washington engages in social media as he listens to astronaut Joe Acaba answer questions, Tuesday, Dec. 4, 2012 at NASA Headquarters. NASA astronaut Joe Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  11. NASA Social

    NASA Image and Video Library

    2012-12-04

    A participant at a NASA Social in Washington listens to astronaut Joe Acaba answer questions about his time living aboard the International Space Station, Tuesday, Dec. 4, 2012 at NASA Headquarters. NASA astronaut Acaba launched to the ISS on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  12. ISS NASA Social

    NASA Image and Video Library

    2013-02-20

    NASA Astronaut Don Pettit, speaks about his experience onboard the International Space Station at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

  13. NASA Astrophysics Technology Needs

    NASA Technical Reports Server (NTRS)

    Stahl, H. Philip

    2012-01-01

    July 2010, NASA Office of Chief Technologist (OCT) initiated an activity to create and maintain a NASA integrated roadmap for 15 key technology areas which recommend an overall technology investment strategy and prioritize NASA?s technology programs to meet NASA?s strategic goals. Science Instruments, Observatories and Sensor Systems(SIOSS) roadmap addresses technology needs to achieve NASA?s highest priority objectives -- not only for the Science Mission Directorate (SMD), but for all of NASA.

  14. Proceedings of the Ninth Annual Summer Conference: NASA/USRA University Advanced Aeronautics Design Program and Advanced Space Design Program

    NASA Technical Reports Server (NTRS)

    1993-01-01

    The NASA/USRA University Advanced Design Program was established in 1984 as an attempt to add more and better design education to primarily undergraduate engineering programs. The original focus of the pilot program encompassing nine universities and five NASA centers was on space design. Two years later, the program was expanded to include aeronautics design with six universities and three NASA centers participating. This year marks the last of a three-year cycle of participation by forty-one universities, eight NASA centers, and one industry participant. The Advanced Space Design Program offers universities an opportunity to plan and design missions and hardware that would be of usc in the future as NASA enters a new era of exploration and discovery, while the Advanced Aeronautics Design Program generally offers opportunities for study of design problems closer to the present time, ranging from small, slow-speed vehicles to large, supersonic and hypersonic passenger transports. The systems approach to the design problem is emphasized in both the space and aeronautics projects. The student teams pursue the chosen problem during their senior year in a one- or two-semester capstone design course and submit a comprehensive written report at the conclusion of the project. Finally, student representatives from each of the universities summarize their work in oral presentations at the Annual Summer Conference, sponsored by one of the NASA centers and attended by the university faculty, NASA and USRA personnel and aerospace industry representatives. As the Advanced Design Program has grown in size, it has also matured in terms of the quality of the student projects. The present volume represents the student work accomplished during the 1992-1993 academic year reported at the Ninth Annual Summer Conference hosted by NASA Lyndon B. Johnson Space Center, June 14-18, 1993.

  15. Subsequent primary malignancies after diffuse large B-cell lymphoma in the modern treatment era.

    PubMed

    Tao, Li; Clarke, Christina A; Rosenberg, Aaron S; Advani, Ranjana H; Jonas, Brian A; Flowers, Christopher R; Keegan, Theresa H M

    2017-07-01

    With the addition of rituximab and other treatment advances, survival after diffuse large B-cell lymphoma (DLBCL) has improved, but subsequent primary malignancies (SPMs) have emerged as an important challenge for DLBCL survivorship. We calculated standardized incidence ratios (SIRs) and 95% confidence intervals (CIs) for SPMs among 23 879 patients who survived at least 1 year after a first primary DLBCL diagnosed during 1989-2012, compared to the general population in California. Cumulative incidence (CMI) of SPMs, accounting for the competing risk of death, also was calculated. We found that the incidence of acute myeloid leukaemia (AML) nearly doubled in the post-rituximab era [SIR (95% CI) 4·39 (2·51-7·13) pre- (1989-2000) and 8·70 (6·62-11·22) post-rituximab (2001-2012)]. Subsequent thyroid cancer was rare pre-rituximab, but increased substantially after 2001 [0·66 (0·08-2·37) vs. 2·27(1·44-3·41)]. The 5-year CMI for all SPMs (4·77% pre- vs. 5·41% post-rituximab, P = 0·047), AML (0·15% vs. 0·41%, P = 0·003), thyroid cancer (0·03% vs. 0·15%, P = 0·003) and melanoma (0·25% vs. 0·42%, P = 0·020) were greater in DLBCL patients diagnosed in the post- versus pre-rituximab period. This study provides insight into the changing pattern of SPM occurrence after the introduction of rituximab, which may elucidate the aetiology of SPMs and should guide future cancer surveillance efforts among DLBCL patients. © 2017 John Wiley & Sons Ltd.

  16. NASA Social

    NASA Image and Video Library

    2012-12-04

    A participant at a NASA Social in Washington tweets as he listens to astronaut Joe Acaba answer questions about his time living aboard the International Space Station, Tuesday, Dec. 4, 2012 at NASA Headquarters. NASA astronaut Joe Acaba launched to the ISS on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  17. NASA historical data book. Volume 4: NASA resources 1969-1978

    NASA Technical Reports Server (NTRS)

    Gawdiak, Ihor Y.; Fedor, Helen

    1994-01-01

    This is Volume 4, NASA Resources 1969-1978, of a series providing a 20-year statistical summary of NASA programs. This series is an important component of NASA published historical reference works, used by NASA personnel, managers, external researchers, and other government agencies. This volume combines statistical data of the component facilities with the data of the parent installation.

  18. NASA historical data book. Volume 1: NASA resources 1958-1968

    NASA Technical Reports Server (NTRS)

    Vannimmen, Jane; Bruno, Leonard C.; Rosholt, Robert L.

    1988-01-01

    This is Volume 1, NASA Resources 1958-1968, of a multi-volume series providing a 20-year compilation of summary statistical and other data descriptive of NASA's programs in aeronautics and manned and unmanned spaceflight. This series is an important component of NASA published historical reference works, used by NASA personnel, managers, external researchers, and other government agencies.

  19. NASA's Education Program

    NASA Technical Reports Server (NTRS)

    1993-01-01

    NASA's current education programs, which will be examined under its Strategic Plan for Education are presented. It is NASA's first goal to maintain this base - revising, expanding, or eliminating programs as necessary. Through NASA's second goal, new education reform initiatives will be added which specifically address NASA mission requirements, national educational reform, and Federal Coordinating Council for Science, Engineering, and Technology (FCCSET) priorities. The chapters in this publication are divided by educational levels, with additional sections on programs to improve the technological competence of students and on an array of NASA published materials to supplement programs. The resource section lists NASA's national and regional Teacher Resource Centers and introduces the reader to NASA's Central Operation of Resources for Educators (CORE), which distributes materials in audiovisual format.

  20. Inflation with a smooth constant-roll to constant-roll era transition

    NASA Astrophysics Data System (ADS)

    Odintsov, S. D.; Oikonomou, V. K.

    2017-07-01

    In this paper, we study canonical scalar field models, with a varying second slow-roll parameter, that allow transitions between constant-roll eras. In the models with two constant-roll eras, it is possible to avoid fine-tunings in the initial conditions of the scalar field. We mainly focus on the stability of the resulting solutions, and we also investigate if these solutions are attractors of the cosmological system. We shall calculate the resulting scalar potential and, by using a numerical approach, we examine the stability and attractor properties of the solutions. As we show, the first constant-roll era is dynamically unstable towards linear perturbations, and the cosmological system is driven by the attractor solution to the final constant-roll era. As we demonstrate, it is possible to have a nearly scale-invariant power spectrum of primordial curvature perturbations in some cases; however, this is strongly model dependent and depends on the rate of the final constant-roll era. Finally, we present, in brief, the essential features of a model that allows oscillations between constant-roll eras.

  1. ISS NASA Social

    NASA Image and Video Library

    2013-02-20

    Marshall Porterfield, Life and Physical Sciences Division Director at NASA Headquarters, talks about the human body in microgravity and other life sciences at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

  2. ISS NASA Social

    NASA Image and Video Library

    2013-02-20

    A NASA Social participant asks a question to the astronauts onboard the International Space Station in a live downlink from the ISS at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

  3. [Recent crisis of psychiatry in the context of modern and postmodern science].

    PubMed

    Petho, Bertalan

    2008-01-01

    We have investigated the recent crisis of psychiatry in perspective of the last two centuries of its history. First and longer part of this period belongs to the Modern era. The second part beginning in the sixties of the last century is the Postmodern era, the one we live in today. We have pointed out that the recent crisis has not come by accident but as one of the several changes characterising our transition into the era labelled "Postmodern". The crisis of psychiatry was analysed in respect of the development of science and in social context. We focused on psychiatry and science and their interconnectedness in their historical articulations. A way out of the crisis of the current era can be found also with the use of historical methods. Science is changing both in respect of its quality and its role in our age. Taking into consideration normal and post-normal science, we differentiated two additional generations of science, pro-normal science and perato-scientia, in the most recent history. On the one hand, psychiatry serves as a paradigm for the conceptualisation of contemporary science. On the other hand, as an up-to-date science re-conceptualised partly according to its own paradigm it may find a way out of its own crisis. The many facets of the current crisis were demonstrated by analysing recent developments of the Hungarian health politics. Concerning this topic we adopted the term "economicity" elaborated by us earlier. We found that psychiatry operated by the hegemony of the rules of economicity might become a relay station for selecting patients to be thrown away as human garbage. This catastrophic outcome may occur if a political system is organized purely by economicity rules without either historical responsibility or local solidarity. However, up-to-date trends of scientificity as shown by pro-normal science and perato-scientia guarantee a radically different course for psychiatry. Following this course, which is consistent with the insight into

  4. Spatial heterogeneity in sulfur isotopes: implications for modern environments and paleoenvironmental reconstructions

    NASA Astrophysics Data System (ADS)

    Fike, D. A.; Jones, D. S.; Fischer, W. W.

    2011-12-01

    Sulfur isotope ratio data have been used to provide significant insights into global biogeochemical cycling over Earth history. In addition to providing a framework for the construction of global redox budgets, these observations also provide the primary constraints on the advent and environmental importance of particular microbial metabolisms. As the chemostratigraphic record has become better resolved in space and time, however, reports of coeval discordant data are increasingly common - both within and between individual sedimentary basins. If accurate, this variability challenges our understanding of the first order behavior of the 'global' sulfur biogeochemical cycle. Some of this discordance may be due to spatial gradients in important oceanographic parameters; however, we think that a more likely culprit is ongoing microbial metabolic activity (that impacts the isotopic composition recorded by geological samples) during both syndepositional sediment reworking and early diagenetic lithification. Modern studies have recently highlighted the efficacy with which microbial activity during sediment remobilization can dramatically alter isotopic profiles. Further, the magnitude of local, microbially driven variations in S isotopes in modern sediments is sufficiently large that uneven incorporation of these signatures during deposition and lithification can explain much of the observed discordance in chemostratigraphic reconstructions of sulfur cycling. Here we attempt to link spatial variability in the sedimentary rock record with understanding of modern microbial systems operating in marine sediments. To that end we examine chemostratigraphic records of sulfur isotope (δ34S) data spanning the terminal Neoproterozoic to early Paleozoic eras and assess their scales of spatial reproducibility. We can gain insight into interpreting the observed patterns in these records by examining modern (bio)sedimentary environments. This understanding also allows us to reflect on

  5. NASA strategic plan

    NASA Technical Reports Server (NTRS)

    1994-01-01

    The NASA Strategic Plan is a living document. It provides far-reaching goals and objectives to create stability for NASA's efforts. The Plan presents NASA's top-level strategy: it articulates what NASA does and for whom; it differentiates between ends and means; it states where NASA is going and what NASA intends to do to get there. This Plan is not a budget document, nor does it present priorities for current or future programs. Rather, it establishes a framework for shaping NASA's activities and developing a balanced set of priorities across the Agency. Such priorities will then be reflected in the NASA budget. The document includes vision, mission, and goals; external environment; conceptual framework; strategic enterprises (Mission to Planet Earth, aeronautics, human exploration and development of space, scientific research, space technology, and synergy); strategic functions (transportation to space, space communications, human resources, and physical resources); values and operating principles; implementing strategy; and senior management team concurrence.

  6. The roles of ERAS during cell lineage specification of mouse early embryonic development.

    PubMed

    Zhao, Zhen-Ao; Yu, Yang; Ma, Huai-Xiao; Wang, Xiao-Xiao; Lu, Xukun; Zhai, Yanhua; Zhang, Xiaoxin; Wang, Haibin; Li, Lei

    2015-08-01

    Eras encodes a Ras-like GTPase protein that was originally identified as an embryonic stem cell-specific Ras. ERAS has been known to be required for the growth of embryonic stem cells and stimulates somatic cell reprogramming, suggesting its roles on mouse early embryonic development. We now report a dynamic expression pattern of Eras during mouse peri-implantation development: its expression increases at the blastocyst stage, and specifically decreases in E7.5 mesoderm. In accordance with its expression pattern, the increased expression of Eras promotes cell proliferation through controlling AKT activation and the commitment from ground to primed state through ERK activation in mouse embryonic stem cells; and the reduced expression of Eras facilitates primitive streak and mesoderm formation through AKT inhibition during gastrulation. The expression of Eras is finely regulated to match its roles in mouse early embryonic development during which Eras expression is negatively regulated by the β-catenin pathway. Thus, beyond its well-known role on cell proliferation, ERAS may also play important roles in cell lineage specification during mouse early embryonic development. © 2015 The Authors.

  7. Gunpowder, the Prince of Wales's feathers and the origins of modern military surgery.

    PubMed

    Pearn, John

    2012-04-01

    The history of military surgery claims many forebears. The first surgeon-soldiers were Homer's Machaon and Podalirius, followed a thousand years later by the Roman surgeons-general, Antonius Musa and Euphorbus; and later, e.g. Ambrose Paré, John Hunter and Sir John Pringle; and the 19th century innovators, Dominique-Jean Larrey (France), Friedrich von Esmarch (Prussia) and the Russian, Nikolai Pirogoff. The singular feature that distinguished modern military surgery from its earlier practice was the use of gunpowder. It was one of two inventions (the other was printing) that by the empowerment of individuals, lifted Western humankind from the medieval to the modern era. Research of primary and secondary archives. Gunpowder was first used in European warfare at Algeceras (1344-1368). Hitherto, the destruction of tissue had been the result of (relative) low-energy wounding with tissue damage caused by incisional or crushing wounds. The founder of modern surgery, Master John of Arderne (1307-1380), wrote of his experience gained as a military surgeon on the battlefield at Crecy (1346). Following Crecy, Arderne was the only chronicler who described the origins of the Prince of Wales's feathers as a royal and later commercial symbol, and the motto 'Ich Dien', 'I serve', as that of hospitals in the Western World. Later advances in military surgery incorporated both clinical experimentation and the innovation of new systems of pre-hospital battlefield care. © 2012 The Author. ANZ Journal of Surgery © 2012 Royal Australasian College of Surgeons.

  8. Enhancing Global Land Surface Hydrology Estimates from the NASA MERRA Reanalysis Using Precipitation Observations and Model Parameter Adjustments

    NASA Technical Reports Server (NTRS)

    Reichle, Rolf; Koster, Randal; DeLannoy, Gabrielle; Forman, Barton; Liu, Qing; Mahanama, Sarith; Toure, Ally

    2011-01-01

    The Modern-Era Retrospective analysis for Research and Applications (MERRA) is a state-of-the-art reanalysis that provides. in addition to atmospheric fields. global estimates of soil moisture, latent heat flux. snow. and runoff for J 979-present. This study introduces a supplemental and improved set of land surface hydrological fields ('MERRA-Land') generated by replaying a revised version of the land component of the MERRA system. Specifically. the MERRA-Land estimates benefit from corrections to the precipitation forcing with the Global Precipitation Climatology Project pentad product (version 2.1) and from revised parameters in the rainfall interception model, changes that effectively correct for known limitations in the MERRA land surface meteorological forcings. The skill (defined as the correlation coefficient of the anomaly time series) in land surface hydrological fields from MERRA and MERRA-Land is assessed here against observations and compared to the skill of the state-of-the-art ERA-Interim reanalysis. MERRA-Land and ERA-Interim root zone soil moisture skills (against in situ observations at 85 US stations) are comparable and significantly greater than that of MERRA. Throughout the northern hemisphere, MERRA and MERRA-Land agree reasonably well with in situ snow depth measurements (from 583 stations) and with snow water equivalent from an independent analysis. Runoff skill (against naturalized stream flow observations from 15 basins in the western US) of MERRA and MERRA-Land is typically higher than that of ERA-Interim. With a few exceptions. the MERRA-Land data appear more accurate than the original MERRA estimates and are thus recommended for those interested in using '\\-tERRA output for land surface hydrological studies.

  9. LADEE NASA Social

    NASA Image and Video Library

    2013-09-05

    NASA Associate Administrator for the Science Mission Directorate John Grunsfeld talks during a NASA Social about the Lunar Atmosphere and Dust Environment Explorer (LADEE) mission at the NASA Wallops Flight Facility, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

  10. LADEE NASA Social

    NASA Image and Video Library

    2013-09-05

    NASA Lunar Atmosphere and Dust Environment Explorer (LADEE) Program Scientist Sarah Noble talks during a NASA Social about the LADEE mission at NASA Wallops Flight Facility, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

  11. LADEE NASA Social

    NASA Image and Video Library

    2013-09-05

    Bob Barber, Lunar Atmosphere and Dust Environment Explorer (LADEE) Spacecraft Systems Engineer at NASA Ames Research Center, points to a model of the LADEE spacecraft a NASA Social, Thursday, Sept. 5, 2013 at NASA Wallops Flight Facility in Virginia. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

  12. Spawning of Massive Antarctic Iceberg Captured by NASA

    NASA Image and Video Library

    2017-07-14

    Between July 10 and 12, 2017, the Larsen C Ice Shelf in West Antarctica calved one of the largest icebergs in history (named "A-68"), weighing approximately one trillion tons. The rift in the ice shelf that spawned the iceberg has been present on the shelf since at least the beginning of the Landsat era (approximately the 1970s), but remained relatively dormant until around 2012, when it was observed actively moving through a suture zone in the ice shelf (Jansen et al., 2015). Suture zones are wide bands of ice that extend from glacier grounding lines (the boundary between a floating ice shelf and ice resting on bedrock) to the sea comprised of a frozen mixture of glacial ice and sea water, traditionally considered to be stabilizing features in ice shelves. When the Antarctic entered its annual dark period in late April, scientists knew the rift only had a few more miles to go before it completely calved the large iceberg. However, due to the lack of sunlight during the Antarctic winter, visible imagery is generally not available each year between May and August. This frame is from an animation that shows the ice shelf as imaged by the NASA/NOAA satellite Suomi NPP, which features the VIIRS (Visible Infrared Imaging Radiometer Suite) instrument. VIIRS has a day/night panchromatic band capable of collecting nighttime imagery of Earth with a spatial resolution of 2,460 feet (750 meters). An image from the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument on NASA's Terra satellite shows the last cloud-free, daytime image of the ice shelf on April 6; the MODIS thermal imagery band is shown on April 29. The images from May 9 to July 14 show available cloud-free imagery from Suomi NPP. Luckily, despite several cloudy days leading up to the break, the weather mostly cleared on July 11, allowing scientists to see the newly formed iceberg on July 12. The animation is available at https://photojournal.jpl.nasa.gov/catalog/PIA21785

  13. Evaluation of Cloud Physical Properties of ECMWF Analysis and Re-Analysis (ERA-40 and ERA Interim) against CERES Tropical Deep Convective Cloud Object Observations

    NASA Technical Reports Server (NTRS)

    Xu, Kuan-Man

    2008-01-01

    This study presents an approach that converts the vertical profiles of grid-averaged cloud properties from large-scale models to probability density functions (pdfs) of subgrid-cell cloud physical properties measured at satellite footprints. Cloud physical and radiative properties, rather than just cloud and precipitation occurrences, of assimilated cloud systems by the European Center for Medium-range Weather Forecasts (ECMWF) operational analysis (EOA) and ECMWF Re-Analyses (ERA-40 and ERA Interim) are validated against those obtained from Earth Observing System satellite cloud object data for January-August 1998 and March 2000 periods. These properties include ice water path (IWP), cloud-top height and temperature, cloud optical depth and solar and infrared radiative fluxes. Each cloud object, a contiguous region with similar cloud physical properties, is temporally and spatially matched with EOA and ERA-40 data. Results indicate that most pdfs of EOA and ERA-40 cloud physical and radiative properties agree with those of satellite observations of the tropical deep convective cloud-object type for the January-August 1998 period. There are, however, significant discrepancies in selected ranges of the cloud property pdfs such as the upper range of EOA cloud top height. A major discrepancy is that the dependence of the pdfs on the cloud object size for both EOA and ERA-40 is not as strong as in the observations. Modifications to the cloud parameterization in ECMWF that occurred in October 1999 eliminate the clouds near the tropopause but shift power of the pdf to lower cloud-top heights and greatly reduce the ranges of IWP and cloud optical depth pdfs. These features persist in ERA-40 due to the use of the same cloud parameterizations. The downgrade of data assimilation technique and the lack of snow water content information in ERA-40, not the coarser horizontal grid resolution, are also responsible for the disagreements with observed pdfs of cloud physical

  14. Next-Generation RS-25 Engines for the NASA Space Launch System

    NASA Technical Reports Server (NTRS)

    Ballard, Richard O.

    2017-01-01

    The utilization of heritage RS-25 engine, also known as the Space Shuttle Main Engine (SSME), has enabled rapid progress in the development and certification of the NASA Space Launch System (SLS) toward operational flight status. The RS-25 brings design maturity and extensive experience gained through 135 missions, 3000+ ground tests, and over a million seconds total accumulated hot-fire time. In addition, there were also over a dozen functional flight assets remaining from the Space Shuttle program that could be leveraged to support the first four flights. Beyond these initial SLS flights, NASA must have a renewed supply of RS-25 engines that must reflect program affordability imperatives as well as technical requirements imposed by the SLS Block-1B vehicle (i.e., 111% RPL power level, reduced service life). Recognizing the long lead times needed for the fabrication, assembly and acceptance testing of flight engines, design activities are underway at NASA and the RS-25 engine provider, Aerojet Rocketdyne, to improve system affordability and eliminate obsolescence concerns. This paper describes how the achievement of these key objectives are enabled largely by utilizing modern materials and fabrication technologies, but also by innovations in systems engineering and integration (SE&I) practices.

  15. NASA Alumni League Dialogue

    NASA Image and Video Library

    2011-03-04

    Former NASA Administrator James Beggs, left, and present NASA Administrator Charles Bolden conduct a dialogue on the future of the space program, Friday, March 4, 2011, at NASA Headquarters in Washington. Beggs was NASA's sixth administrator serving from July 1981 to December 1985. Bolden took over the post as NASA's 12th administrator in July 2009. The dialogue is part of the program “The State of the Agency: NASA Future Programs Presentation” sponsored by the NASA Alumni League with support from the AAS, AIAA, CSE and WIA.Photo Credit: (NASA/Paul E. Alers)

  16. 14 CFR 1240.105 - Special initial awards-NASA and NASA contractor employees.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Special initial awards-NASA and NASA... initial awards—NASA and NASA contractor employees. (a) Patent Application Awards. (1) When the Board... Property or the Patent or Intellectual Property Counsel at a NASA Center that an invention made by an...

  17. Acting Administrator Robert Lightfoot Discusses NASAs FY2018 NASA Budget Request

    NASA Image and Video Library

    2017-05-23

    Acting NASA Administrator Robert Lightfoot discussed the agency’s Fiscal Year 2018 budget request on May 23, during an agencywide town hall State of NASA address at NASA Headquarters in Washington. The address also was broadcast on NASA Television and streamed on the agency’s homepage and mobile apps.

  18. The Incidence of Sixteenth Century Cosmic Models in Modern Texts

    NASA Astrophysics Data System (ADS)

    Maene, S. A.; Best, J. S.; Usher, P. D.

    1999-12-01

    In the sixteenth century, the bounded cosmological models of Copernicus (1543) and Tycho Brahe (1588), and the unbounded model of Thomas Digges (1576), vied with the bounded geocentric model of Ptolemy (c. 140 AD). The work of the philosopher Giordano Bruno in 1584 lent further support to the Digges model. Despite the eventual acceptance of the unbounded universe, analysis of over 100 modern introductory astronomy texts reveals that these early unbounded models are mentioned infrequently. The ratio of mentions of Digges' model to Copernicus' model has the surprisingly low value of R = 0.08. The philosophical speculation of Bruno receives mention more than twice as often (R = 0.17). The expectation that these early unbounded models warrant inclusion in astronomy texts is supported both by modern hindsight and by the literature of the time. In Shakespeare's "Hamlet" of c. 1601, Prince Hamlet suffers from two transformations. According to the cosmic allegorical model, one transformation changes the bounded geocentricism of Ptolemy to the bounded heliocentricism of Copernicus, while the other completes the change to Digges' model of the infinite universe of suns. This interpretation and the modern world view suggest that both transformations should receive equal mention and thus that the ratio R in introductory texts should be close to unity. This work was supported in part by the NASA West Virginia Space Grant Consortium.

  19. Research in NASA history: A guide to the NASA history program

    NASA Technical Reports Server (NTRS)

    1992-01-01

    This report describes the research opportunities and accomplishments of NASA's agency wide history program. It also offers a concise guide to the historical documentary resources available at NASA Headquarters in Washington D.C., at NASA facilities located around the country, and through the federal records system. In addition, this report contains expanded contributions by Lee D. Saegessor and other members of the NASA Headquarters History Division and by those responsible for historical documents and records at some NASA centers.

  20. LADEE NASA Social

    NASA Image and Video Library

    2013-09-05

    NASA Associate Administrator for the Science Mission Directorate John Grunsfeld is seen in a video monitor during a NASA Social about the Lunar Atmosphere and Dust Environment Explorer (LADEE) mission at the NASA Wallops Flight Facility, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

  1. 75 FR 70951 - NASA Advisory Council; NASA Commercial Space Committee; Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-19

    ... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (10-148)] NASA Advisory Council; NASA... Committee of the NASA Advisory Council. DATES: Tuesday, December 14, 2010, 1:30 p.m.-4:30 p.m., Local Time. ADDRESSES: NASA Headquarters, 300 E Street, SW., Glennan Conference Center Room 1Q39, Washington, DC 20546...

  2. ISS NASA Social

    NASA Image and Video Library

    2013-02-20

    Expedition 33/34 astronauts onboard the International Space Station answer questions in a live downlink at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Seen from left to right are NASA astronauts Tom Marshburn, Kevin Ford and Canadian Space Agency (CSA) astronaut Chris Hadfield. Photo Credit: (NASA/Carla Cioffi)

  3. Between Tradition and Modernity: Marriage Dynamics in Kyrgyzstan.

    PubMed

    Nedoluzhko, Lesia; Agadjanian, Victor

    2015-06-01

    The demographic literature on union formation in post-communist Europe typically documents retreat from marriage and increase in cohabitation. However, sociological and anthropological studies of post-Soviet Central Asia often point to a resurgence of various traditional norms and practices, including those surrounding marriage, that were suppressed under Soviet rule. We engage these two perspectives on union formation by analyzing transition to first marriage in Kyrgyzstan both before and after the collapse of the USSR. We use uniquely detailed marriage histories from a nationally representative survey conducted in the period 2011-2012 to examine the dynamics of traditional marital practices among that country's two main ethnic groups-Kyrgyz and Uzbeks-focusing on trends in arranged marriages and in marriages involving bride kidnapping. The analysis reveals instructive ethnic and period differences but also indicates an overall decline in the risks of both types of traditional marriage practices in the post-Soviet era. In fact, although the decline has characterized all marriage types, it was more substantial for traditional marriages. We interpret these trends as evidence of continuing modernization of nuptiality behavior in the region.

  4. Internal NASA Study: NASAs Protoflight Research Initiative

    NASA Technical Reports Server (NTRS)

    Coan, Mary R.; Hirshorn, Steven R.; Moreland, Robert

    2015-01-01

    The NASA Protoflight Research Initiative is an internal NASA study conducted within the Office of the Chief Engineer to better understand the use of Protoflight within NASA. Extensive literature reviews and interviews with key NASA members with experience in both robotic and human spaceflight missions has resulted in three main conclusions and two observations. The first conclusion is that NASA's Protoflight method is not considered to be "prescriptive." The current policies and guidance allows each Program/Project to tailor the Protoflight approach to better meet their needs, goals and objectives. Second, Risk Management plays a key role in implementation of the Protoflight approach. Any deviations from full qualification will be based on the level of acceptable risk with guidance found in NPR 8705.4. Finally, over the past decade (2004 - 2014) only 6% of NASA's Protoflight missions and 6% of NASA's Full qualification missions experienced a publicly disclosed mission failure. In other words, the data indicates that the Protoflight approach, in and of it itself, does not increase the mission risk of in-flight failure. The first observation is that it would be beneficial to document the decision making process on the implementation and use of Protoflight. The second observation is that If a Project/Program chooses to use the Protoflight approach with relevant heritage, it is extremely important that the Program/Project Manager ensures that the current project's requirements falls within the heritage design, component, instrument and/or subsystem's requirements for both the planned and operational use, and that the documentation of the relevant heritage is comprehensive, sufficient and the decision well documented. To further benefit/inform this study, a recommendation to perform a deep dive into 30 missions with accessible data on their testing/verification methodology and decision process to research the differences between Protoflight and Full Qualification

  5. The NASA Severe Thunderstorm Observations and Regional Modeling (NASA STORM) Project

    NASA Technical Reports Server (NTRS)

    Schultz, Christopher J.; Gatlin, Patrick N.; Lang, Timothy J.; Srikishen, Jayanthi; Case, Jonathan L.; Molthan, Andrew L.; Zavodsky, Bradley T.; Bailey, Jeffrey; Blakeslee, Richard J.; Jedlovec, Gary J.

    2016-01-01

    The NASA Severe Storm Thunderstorm Observations and Regional Modeling(NASA STORM) project enhanced NASA’s severe weather research capabilities, building upon existing Earth Science expertise at NASA Marshall Space Flight Center (MSFC). During this project, MSFC extended NASA’s ground-based lightning detection capacity to include a readily deployable lightning mapping array (LMA). NASA STORM also enabled NASA’s Short-term Prediction and Research Transition (SPoRT) to add convection allowing ensemble modeling to its portfolio of regional numerical weather prediction (NWP) capabilities. As a part of NASA STORM, MSFC developed new open-source capabilities for analyzing and displaying weather radar observations integrated from both research and operational networks. These accomplishments enabled by NASA STORM are a step towards enhancing NASA’s capabilities for studying severe weather and positions them for any future NASA related severe storm field campaigns.

  6. NASA Low-Speed Centrifugal Compressor for Fundamental Research

    NASA Technical Reports Server (NTRS)

    Wood, J. R.; Adam, P. W.; Buggele, A. E.

    1983-01-01

    A centrifugal compressor facility being built by the NASA Lewis Research Center is described; its purpose is to obtain benchmark experimental data for internal flow code verification and modeling. The facility will be heavily instrumented with standard pressure and temperature probes and have provisions for flow visualization and laser Doppler velocimetry. The facility will accommodate rotational speeds to 2400 rpm and will be rated at pressures to 1.25 atm. The initial compressor stage for testing is geometrically and dynamically representative of modern high-performance stages with the exception of Mach number levels. Design exit tip speed for the initial stage is 500 ft/sec with a pressure ratio of 1.17. The rotor exit backsweep is 55 deg from radial.

  7. A new state space model for the NASA/JPL 70-meter antenna servo controls

    NASA Technical Reports Server (NTRS)

    Hill, R. E.

    1987-01-01

    A control axis referenced model of the NASA/JPL 70-m antenna structure is combined with the dynamic equations of servo components to produce a comprehansive state variable (matrix) model of the coupled system. An interactive Fortran program for generating the linear system model and computing its salient parameters is described. Results are produced in a state variable, block diagram, and in factored transfer function forms to facilitate design and analysis by classical as well as modern control methods.

  8. NASA Social

    NASA Image and Video Library

    2011-05-18

    Gwynne Shotwell, President of SpaceX, speaks during a NASA Social, Friday, May 18, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

  9. NASA Social

    NASA Image and Video Library

    2012-05-18

    Models of various rockets line a table at a NASA Social, Friday, May 18, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

  10. NASA Alumni League Dialogue

    NASA Image and Video Library

    2011-03-04

    Former NASA Administrator James Beggs is seen during a dialogue with present NASA Administrator Charles Bolden on the future of the space program, Friday, March 4, 2011, at NASA Headquarters in Washington. Beggs was NASA's sixth administrator serving from July 1981 to December 1985. The dialogue was part of the program “The State of the Agency: NASA Future Programs Presentation” sponsored by the NASA Alumni League with support from the AAS, AIAA, CSE and WIA.Photo Credit: (NASA/Paul E. Alers)

  11. ISS NASA Social

    NASA Image and Video Library

    2013-02-20

    Marshall Porterfield, Life and Physical Sciences Division Director at NASA Headquarters, talks about the human body in microgravity and other life sciences at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. In the foreground is pictured Veggie, a container used for growing plants on the ISS. Photo Credit: (NASA/Carla Cioffi)

  12. The second modern condition? Compressed modernity as internalized reflexive cosmopolitization.

    PubMed

    Kyung-Sup, Chang

    2010-09-01

    Compressed modernity is a civilizational condition in which economic, political, social and/or cultural changes occur in an extremely condensed manner in respect to both time and space, and in which the dynamic coexistence of mutually disparate historical and social elements leads to the construction and reconstruction of a highly complex and fluid social system. During what Beck considers the second modern stage of humanity, every society reflexively internalizes cosmopolitanized risks. Societies (or their civilizational conditions) are thereby being internalized into each other, making compressed modernity a universal feature of contemporary societies. This paper theoretically discusses compressed modernity as nationally ramified from reflexive cosmopolitization, and, then, comparatively illustrates varying instances of compressed modernity in advanced capitalist societies, un(der)developed capitalist societies, and system transition societies. In lieu of a conclusion, I point out the declining status of national societies as the dominant unit of (compressed) modernity and the interactive acceleration of compressed modernity among different levels of human life ranging from individuals to the global community. © London School of Economics and Political Science 2010.

  13. NASA HUNCH Hardware

    NASA Technical Reports Server (NTRS)

    Hall, Nancy R.; Wagner, James; Phelps, Amanda

    2014-01-01

    What is NASA HUNCH? High School Students United with NASA to Create Hardware-HUNCH is an instructional partnership between NASA and educational institutions. This partnership benefits both NASA and students. NASA receives cost-effective hardware and soft goods, while students receive real-world hands-on experiences. The 2014-2015 was the 12th year of the HUNCH Program. NASA Glenn Research Center joined the program that already included the NASA Johnson Space Flight Center, Marshall Space Flight Center, Langley Research Center and Goddard Space Flight Center. The program included 76 schools in 24 states and NASA Glenn worked with the following five schools in the HUNCH Build to Print Hardware Program: Medina Career Center, Medina, OH; Cattaraugus Allegheny-BOCES, Olean, NY; Orleans Niagara-BOCES, Medina, NY; Apollo Career Center, Lima, OH; Romeo Engineering and Tech Center, Washington, MI. The schools built various parts of an International Space Station (ISS) middeck stowage locker and learned about manufacturing process and how best to build these components to NASA specifications. For the 2015-2016 school year the schools will be part of a larger group of schools building flight hardware consisting of 20 ISS middeck stowage lockers for the ISS Program. The HUNCH Program consists of: Build to Print Hardware; Build to Print Soft Goods; Design and Prototyping; Culinary Challenge; Implementation: Web Page and Video Production.

  14. NASA Social

    NASA Image and Video Library

    2012-12-04

    A participant at a NASA Social in Washington asks astronaut Joe Acaba a question, Tuesday, Dec. 4, 2012, at NASA Headquarters. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  15. NASA Social

    NASA Image and Video Library

    2012-05-18

    Participants with the NASA Social stand together, Friday, May 18, 2012, in front of the Vehicle Assembly Building (VAB) at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

  16. LADEE NASA Social

    NASA Image and Video Library

    2013-09-05

    Jason Townsend, NASA's Deputy Social Media Manager, kicks off the Lunar Atmosphere and Dust Environment Explorer (LADEE) NASA Social at Wallops Flight Facility, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

  17. ISS NASA Social

    NASA Image and Video Library

    2013-02-20

    William Gerstenmaier, Associate Administrator Human Exploration and Operations, speaks at a NASA Social on Science on the International Space Station at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

  18. FOREWORD: Modern Applications of Timescales Modern Applications of Timescales

    NASA Astrophysics Data System (ADS)

    Arias, E. F.; Lewandowski, W.

    2011-08-01

    The development of the first atomic frequency standard by Louis Essen in the 1950s is at the origin of the adoption of the atomic definition of the SI second by the 13th General Conference on Weights and Measures in 1967 and the consequent adoption of the atomic timescale. After the short reign of ephemeris time as the world's reference timescale from 1954 until 1967, Coordinated Universal Time (UTC), synchronized to universal time UT1, appeared as the best compromise for satisfying the requests of all users. At the moment of the discussion on the adoption of an atomic timescale to replace ephemeris time, the possibility of having both an astronomical time and an atomic time to serve different purposes was discussed. In the words of Essen [1], this 'would cause endless confusion as well as involving duplication of equipment'. Forty years after the adoption of the definition of Coordinated Universal Time at the International Telecommunication Union (ITU), we are close to the moment of making a decision on whether or not to decouple UTC from its tight link to the rotation of the Earth embodied in UT1. It has been a ten-year process of discussion, mainly at the ITU with the input of the International Astronomical Union, the BIPM, the Consultative Committee for Time and Frequency and other organizations. The majority opinion supported the change based on developers and users of systems that need time synchronization to a stable and continuous reference timescale; others insist on the necessity of keeping the leap-second strategy for serving some applications or just for tradition. It is our hope that, as happened in the seventies, the most appropriate definition to serve all modern applications will be adopted with the consensus of the different sectors. The redirection of international timekeeping from astronomy to metrology can be considered the benchmark that started the era of modern timescales, all based on atomic properties. The aim of this special issue of

  19. NASA Video Catalog

    NASA Technical Reports Server (NTRS)

    2006-01-01

    This issue of the NASA Video Catalog cites video productions listed in the NASA STI database. The videos listed have been developed by the NASA centers, covering Shuttle mission press conferences; fly-bys of planets; aircraft design, testing and performance; environmental pollution; lunar and planetary exploration; and many other categories related to manned and unmanned space exploration. Each entry in the publication consists of a standard bibliographic citation accompanied by an abstract. The Table of Contents shows how the entries are arranged by divisions and categories according to the NASA Scope and Subject Category Guide. For users with specific information, a Title Index is available. A Subject Term Index, based on the NASA Thesaurus, is also included. Guidelines for usage of NASA audio/visual material, ordering information, and order forms are also available.

  20. Jorge Luis Borges and the New Physics: the Literature of Modern Science and the Science of Modern Literature

    NASA Astrophysics Data System (ADS)

    Mosher, Mark Robert

    1992-01-01

    By examining the works of the Argentine writer, Jorge Luis Borges, and the parallels it has with modern physics, literature and science converge in their quest for truth regarding the structure and meaning of the universe. The classical perception of physics as a "hard" science--that of quantitative, rational thought which was established during the Newtonian era--has been replaced by the "new physics," which integrates the so-called "soft" elements into its paradigm. It presents us with a universe based not exclusively on a series of particle-like interactions, or a "billiard-ball" hypothesis where discrete objects have a measurable position and velocity in absolute space and time, but rather on a combination of these mechanistic properties and those that make up the non-physical side of nature such as intuition, consciousness, and emotion. According to physicists like James Jeans science has been "humanized" to the extent that the universe as a "great machine" has been converted into a "great thought.". In nearly all his collections of essays and short stories, Borges complements the new physics by producing a literature that can be described as "scientized." The abstract, metaphysical implications and concerns of the new world-view, such as space, time, language, consciousness, free will, determinism, etc., appear repeatedly throughout Borges' texts, and are treated in terms that are remarkably similar to those expressed in the scientific texts whose authors include Albert Einstein, Niels Bohr, Werner Heisenberg, and Erwin Schrodinger. As a final comparison, Borges and post-modern physicists address the question of the individual's ability to ever comprehend the universe. They share an attitude of incredulity toward all models and theories of reality simply because they are based on partial information, and therefore seen only as conjectures.

  1. The Legacy of ERA, Privatization and the Policy Ratchet

    ERIC Educational Resources Information Center

    Ball, Stephen J.

    2008-01-01

    This article explores the ways in which the neo-liberal impetus toward the privatization of state schooling signalled in the Education Reform Act 1988 (ERA) has become embedded in the English school system. Four main points are made. First, that ERA itself was of huge strategic rather than substantive importance as far as privatization is…

  2. NASA Systems Engineering Handbook

    NASA Technical Reports Server (NTRS)

    Shishko, Robert; Aster, Robert; Chamberlain, Robert G.; Mcduffee, Patrick; Pieniazek, Les; Rowell, Tom; Bain, Beth; Cox, Renee I.; Mooz, Harold; Polaski, Lou

    1995-01-01

    This handbook brings the fundamental concepts and techniques of systems engineering to NASA personnel in a way that recognizes the nature of NASA systems and environment. It is intended to accompany formal NASA training courses on systems engineering and project management when appropriate, and is designed to be a top-level overview. The concepts were drawn from NASA field center handbooks, NMI's/NHB's, the work of the NASA-wide Systems Engineering Working Group and the Systems Engineering Process Improvement Task team, several non-NASA textbooks and guides, and material from independent systems engineering courses taught to NASA personnel. Five core chapters cover systems engineering fundamentals, the NASA Project Cycle, management issues in systems engineering, systems analysis and modeling, and specialty engineering integration. It is not intended as a directive. Superseded by: NASA/SP-2007-6105 Rev 1 (20080008301).

  3. NASA Social

    NASA Image and Video Library

    2012-05-18

    NASA Social participants are reflected in the sunglasses of former NASA astronaut Garrett Reisman, now a senior engineer working on astronaut safety and mission assurance for Space Exploration Technologies, or SpaceX, as he speaks with them, Friday, May 18, 2012, at the launch complex where the company's Falcon 9 rocket is set to launch early Friday morning at Cape Canaveral Air Force Station in Cape Canaveral, Fla. Photo Credit: (NASA/Paul E. Alers)

  4. NASA Alumni League Dialogue

    NASA Image and Video Library

    2011-03-04

    Former NASA Administrator James Beggs smiles during a dialogue on the future of the space program, Friday, March 4, 2011, at NASA Headquarters in Washington. Beggs was NASA's sixth administrator serving from July 1981 to December 1985. The dialogue was part of the program “The State of the Agency: NASA Future Programs Presentation” sponsored by the NASA Alumni League with support from the AAS, AIAA, CSE and WIA.Photo Credit: (NASA/Paul E. Alers)

  5. Modernizing Earth and Space Science Modeling Workflows in the Big Data Era

    NASA Astrophysics Data System (ADS)

    Kinter, J. L.; Feigelson, E.; Walker, R. J.; Tino, C.

    2017-12-01

    Modeling is a major aspect of the Earth and space science research. The development of numerical models of the Earth system, planetary systems or astrophysical systems is essential to linking theory with observations. Optimal use of observations that are quite expensive to obtain and maintain typically requires data assimilation that involves numerical models. In the Earth sciences, models of the physical climate system are typically used for data assimilation, climate projection, and inter-disciplinary research, spanning applications from analysis of multi-sensor data sets to decision-making in climate-sensitive sectors with applications to ecosystems, hazards, and various biogeochemical processes. In space physics, most models are from first principles, require considerable expertise to run and are frequently modified significantly for each case study. The volume and variety of model output data from modeling Earth and space systems are rapidly increasing and have reached a scale where human interaction with data is prohibitively inefficient. A major barrier to progress is that modeling workflows isn't deemed by practitioners to be a design problem. Existing workflows have been created by a slow accretion of software, typically based on undocumented, inflexible scripts haphazardly modified by a succession of scientists and students not trained in modern software engineering methods. As a result, existing modeling workflows suffer from an inability to onboard new datasets into models; an inability to keep pace with accelerating data production rates; and irreproducibility, among other problems. These factors are creating an untenable situation for those conducting and supporting Earth system and space science. Improving modeling workflows requires investments in hardware, software and human resources. This paper describes the critical path issues that must be targeted to accelerate modeling workflows, including script modularization, parallelization, and

  6. The Modern Value of Early Writings in Medicine and Dentistry.

    PubMed

    Peck, Sheldon

    2016-01-01

    This article illustrates three examples supporting the modern value of early writings in dentistry and medicine. First, by studying cases described in works published long before the era of genetic science, we are able to develop new hypotheses about familial conditions and their genetic roots. Tooth transposition is presented as an example. Second, old writings may lead us to valuable historical insights and perspectives in medicine that can be revealed only in retrospective analysis. An example of this kind of historical analysis uncovers why dentistry became unnaturally separated from mainstream medicine in the 19th century. Third, early writings become keys to unlocking forgotten knowledge that enriches our understanding of historically significant people and events. The discovery of Norman Kingsley's long forgotten pyrographic paintings after Rembrandt portraits is used as an example. Libraries, the traditional custodians of these valued old texts, must continue to be supported, and not undermined by the paperless digital revolution. Copyright American Academy of the History of Dentistry.

  7. Applied imaging at the NASA Lewis Research Center

    NASA Astrophysics Data System (ADS)

    Slater, Howard A.; Owens, Jay C.

    1993-01-01

    NASA Lewis Research Center in Cleveland, Ohio has just completed the celebration of its 50th anniversary. `During the past 50 years, Lewis helped win World War II, made jet aircraft safer and more efficient, helped Americans land on the Moon ... and engaged in the type of fundamental research that benefits all of us in our daily lives.' As part of the center's long history, the Photographic and Printing Branch has continued to develop and meet the center's research imaging requirements. As imaging systems continue to advance and researchers more clearly understand the power of imaging, investigators are relying more and more on imaging systems to meet program objectives. Today, the Photographic and Printing Branch supports a research community of over 5,000 including advocacy for NASA Headquarters and other government agencies. Complete classified and unclassified imaging services include high- speed image acquisition, technical film and video documentaries, still imaging, and conventional and unconventional photofinishing operations. These are the foundation of the branch's modern support function. This paper provides an overview of the varied applied imaging programs managed by the Photographic and Printing Branch. Emphasis is placed on recent imaging projects including icing research, space experiments, and an on-line image archive.

  8. @NASA Wins Shorty Award

    NASA Image and Video Library

    2013-04-10

    A Shorty Award is seen Wednesday, April 10, 2013 at NASA Headquarters in Washington. NASA's official Twitter feed, @NASA, has won its second consecutive Shorty award for the best government use of social media. The Shorty Award honors the best of social media across sites such as Twitter, Facebook, Tumblr, YouTube, Foursquare and others. NASA took the prize Monday, April 8, at the fifth Shorty Awards ceremony in New York. The @NASA acceptance tweet was, "We're sharing the universe 1 tweet at a time. Be inspired! Follow @NASA & RT if you love science & space. #ShortyAwards." Photo Credit: (NASA/Carla Cioffi)

  9. The potential for a new era of supersonic and hypersonic aviation

    NASA Technical Reports Server (NTRS)

    Harris, Roy V.

    1990-01-01

    A new era of supersonic and hypersonic aviation is envisioned. The potential for supersonic and hypersonic flight vehicles in this new era is analyzed. Technology challenges that must be met in order to bring in this new era of flight are discussed. The current technical status and future potential are cited in the areas of aerodynamics, propulsion, and structural materials. A next major step in the development of high-speed air transportation is suggested.

  10. Using NASA`s Airborne Topographic Mapper IV to Quantify Geomorphic Change in Arid Southwestern Stream Systems

    NASA Astrophysics Data System (ADS)

    Finnegan, D. C.; Krabill, W.; Lichvar, R. W.; Ericsson, M. P.; Frederick, E.; Manizade, S.; Yungel, J.; Sonntag, J.; Swift, R.

    2005-12-01

    Understanding how arid stream systems respond to individual climatic events is often difficult given the dynamic and `flashy' nature of most watersheds and the unpredictable nature of individual storm events. Until recently conventional methods for quantifying change dictated the use of stream gauge measurements coupled with periodic cross-section measurements to quantify changes in large-scale channel geometry. Using this approach to quantify change across large areas often proves to be impractical and unattainable given the laborious nature of most surveying techniques including modern GPS systems. Alternately, airborne laser technologies such as NASA's Airborne Topographic Mapper (ATM) are capable of quantifying small-scale changes (~5-10cm) across large-scale terrain rapidly and accurately. The ATM was developed at the NASA-GSFC Wallops Flight Facility. Its current version, ATM-4, measures topography 5,000 times per second across a 45-degree swath below the aircraft by transmitting a 532nm (green) laser pulse and receiving the backscattered signal in a high-speed waveform digitizer. The laser range measurements are combined with aircraft location from GPS and attitude from an inertial navigation system (INS) to provide a precise XYZ coordinate for each (~1-meter diameter) laser footprint on the ground. Our work focuses on the use of airborne laser altimetry to quantify the nature of individual surfaces and the geomorphic change that occurs within small arid stream systems during significant storm events. In September of 2003 and 2005 acquisition surveys using NASA's ATM-IV were flown over Mission Creek, a small arid stream system in Southern California's Mojave Desert with a relatively long gauging history (>40yrs), allowing us to quantify the geomorphic change occurring within the channel as a result of the record storm events during the winter of 2004-2005. Preliminary results associated with our work are encouraging and lead us to believe that when compared

  11. NASA - Beyond Boundaries

    NASA Technical Reports Server (NTRS)

    McMillan, Courtenay

    2016-01-01

    NASA is able to achieve human spaceflight goals in partnership with international and commercial teams by establishing common goals and building connections. Presentation includes photographs from NASA missions - on orbit, in Mission Control, and at other NASA facilities.

  12. Working at NASA

    NASA Technical Reports Server (NTRS)

    Harding, Adam

    2010-01-01

    This slide presentation reviews the author's educational and work background prior to working at NASA. It then presents an overview of NASA Dryden, a brief review of the author's projects while working at NASA, and some closing thoughts.

  13. Disseminating NASA-based science through NASA's Universe of Learning: Girls STEAM Ahead

    NASA Astrophysics Data System (ADS)

    Marcucci, E.; Meinke, B. K.; Smith, D. A.; Ryer, H.; Slivinski, C.; Kenney, J.; Arcand, K.; Cominsky, L.

    2017-12-01

    The Girls STEAM Ahead with NASA (GSAWN) initiative partners the NASA's Universe of Learning (UoL) resources with public libraries to provide NASA-themed activities for girls and their families. The program expands upon the legacy program, NASA Science4Girls and Their Families, in celebration of National Women's History Month. Program resources include hands-on activities for engaging girls, such as coding experiences and use of remote telescopes, complementary exhibits, and professional development for library partner staff. The science-institute-embedded partners in NASA's UoL are uniquely poised to foster collaboration between scientists with content expertise and educators with pedagogy expertise. The thematic topics related to NASA Astrophysics enable audiences to experience the full range of NASA scientific and technical disciplines and the different career skills each requires. For example, an activity may focus on understanding exoplanets, methods of their detection, and characteristics that can be determined remotely. The events focus on engaging underserved and underrepresented audiences in Science, Technology, Engineering, and Mathematics (STEM) via use of research-based best practices, collaborations with libraries, partnerships with local and national organizations (e.g. National Girls Collaborative Project or NGCP), and remote engagement of audiences. NASA's UoL collaborated with another NASA STEM Activation partner, NASA@ My Library, to announce GSAWN to their extensive STAR_Net network of libraries. This partnership between NASA SMD-funded Science learning and literacy teams has included NASA@ My Library hosting a professional development webinar featuring a GSAWN activity, a newsletter and blog post about the program, and plans for future exhibit development. This presentation will provide an overview of the program's progress to engage girls and their families through the development and dissemination of NASA-based science programming.

  14. LADEE NASA Social

    NASA Image and Video Library

    2013-09-05

    A participant at a NASA Social on the Lunar Atmosphere and Dust Environment Explorer (LADEE) mission asks NASA Associate Administrator for the Science Mission Directorate John Grunsfeld a question, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

  15. NASA Pocket Statistics

    NASA Technical Reports Server (NTRS)

    1995-01-01

    NASA Pocket Statistics is published for the use of NASA managers and their staff. Included herein is Administrative and Organizational information, summaries of Space Flight Activity including the NASA Major Launch Record, and NASA Procurement, Financial, and Manpower data. The NASA Major Launch Record includes all launches of Scout class and larger vehicles. Vehicle and spacecraft development flights are also included in the Major Launch Record. Shuttle missions are counted as one launch and one payload, where free flying payloads are not involved. Satellites deployed from the cargo bay of the Shuttle and placed in a separate orbit or trajectory are counted as an additional payload.

  16. NASA Future Forum

    NASA Image and Video Library

    2012-02-21

    NASA Chief Technologist Mason Peck talks during the NASA Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

  17. NASA Future Forum

    NASA Image and Video Library

    2012-02-21

    NASA Deputy Administrator Lori Garver speaks during the NASA Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

  18. NASA Social

    NASA Image and Video Library

    2012-12-04

    NASA Social participants listen as astronaut Joe Acaba answers questions about his time living aboard the International Space Station at NASA Headquarters, Tuesday, Dec. 4, 2012 in Washington. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

  19. ISS NASA Social

    NASA Image and Video Library

    2013-02-20

    Tara Ruttley, International Space Station Program Scientist, talks about the benefits of conducting science experiments on ISS at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

  20. NASA Future Forum

    NASA Image and Video Library

    2011-08-11

    NASA Administrator Charles Bolden delivers opening remarks at the NASA Future Forum held at the Riggs Alumni Center on the campus of the University of Maryland, Thursday, Aug. 11, 2011 in College Park, Md. Photo Credit: (NASA/Paul E. Alers)

  1. 14 CFR § 1240.105 - Special initial awards-NASA and NASA contractor employees.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 14 Aeronautics and Space 5 2014-01-01 2014-01-01 false Special initial awards-NASA and NASA... initial awards—NASA and NASA contractor employees. (a) Patent Application Awards. (1) When the Board... Property or the Patent or Intellectual Property Counsel at a NASA Center that an invention made by an...

  2. The NASA Astrophysics Program

    NASA Technical Reports Server (NTRS)

    Zebulum, Ricardo S.

    2011-01-01

    NASA's scientists are enjoying unprecedented access to astronomy data from space, both from missions launched and operated only by NASA, as well as missions led by other space agencies to which NASA contributed instruments or technology. This paper describes the NASA astrophysics program for the next decade, including NASA's response to the ASTRO2010 Decadal Survey.

  3. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Electronics control module for the NASA Bioreactor. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  4. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Interior view of the gas supply for the NASA Bioreactor. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  5. Gauss-Bonnet cosmology unifying late and early-time acceleration eras with intermediate eras

    NASA Astrophysics Data System (ADS)

    Oikonomou, V. K.

    2016-07-01

    In this paper we demonstrate that with vacuum F(G) gravity it is possible to describe the unification of late and early-time acceleration eras with the radiation and matter domination era. The Hubble rate of the unified evolution contains two mild singularities, so called Type IV singularities, and the evolution itself has some appealing features, such as the existence of a deceleration-acceleration transition at late times. We also address quantitatively a fundamental question related to modified gravity models description of cosmological evolution: Is it possible for all modified gravity descriptions of our Universe evolution, to produce a nearly scale invariant spectrum of primordial curvature perturbations? As we demonstrate, the answer for the F(G) description is no, since the resulting power spectrum is not scale invariant, in contrast to the F(R) description studied in the literature. Therefore, although the cosmological evolution can be realized in the context of vacuum F(G) gravity, the evolution is not compatible with the observational data, in contrast to the F(R) gravity description of the same cosmological evolution.

  6. NASA systems engineering handbook

    NASA Astrophysics Data System (ADS)

    Shishko, Robert; Aster, Robert; Chamberlain, Robert G.; McDuffee, Patrick; Pieniazek, Les; Rowell, Tom; Bain, Beth; Cox, Renee I.; Mooz, Harold; Polaski, Lou

    1995-06-01

    This handbook brings the fundamental concepts and techniques of systems engineering to NASA personnel in a way that recognizes the nature of NASA systems and environment. It is intended to accompany formal NASA training courses on systems engineering and project management when appropriate, and is designed to be a top-level overview. The concepts were drawn from NASA field center handbooks, NMI's/NHB's, the work of the NASA-wide Systems Engineering Working Group and the Systems Engineering Process Improvement Task team, several non-NASA textbooks and guides, and material from independent systems engineering courses taught to NASA personnel. Five core chapters cover systems engineering fundamentals, the NASA Project Cycle, management issues in systems engineering, systems analysis and modeling, and specialty engineering integration. It is not intended as a directive.

  7. NASA Future Forum

    NASA Image and Video Library

    2012-02-21

    NASA Public Affairs Officer Lauren Worley kicks off the second day of the NASA Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

  8. A Portable Regional Weather and Climate Downscaling System Using GEOS-5, LIS-6, WRF, and the NASA Workflow Tool

    NASA Astrophysics Data System (ADS)

    Kemp, E. M.; Putman, W. M.; Gurganus, J.; Burns, R. W.; Damon, M. R.; McConaughy, G. R.; Seablom, M. S.; Wojcik, G. S.

    2009-12-01

    We present a regional downscaling system (RDS) suitable for high-resolution weather and climate simulations in multiple supercomputing environments. The RDS is built on the NASA Workflow Tool, a software framework for configuring, running, and managing computer models on multiple platforms with a graphical user interface. The Workflow Tool is used to run the NASA Goddard Earth Observing System Model Version 5 (GEOS-5), a global atmospheric-ocean model for weather and climate simulations down to 1/4 degree resolution; the NASA Land Information System Version 6 (LIS-6), a land surface modeling system that can simulate soil temperature and moisture profiles; and the Weather Research and Forecasting (WRF) community model, a limited-area atmospheric model for weather and climate simulations down to 1-km resolution. The Workflow Tool allows users to customize model settings to user needs; saves and organizes simulation experiments; distributes model runs across different computer clusters (e.g., the DISCOVER cluster at Goddard Space Flight Center, the Cray CX-1 Desktop Supercomputer, etc.); and handles all file transfers and network communications (e.g., scp connections). Together, the RDS is intended to aid researchers by making simulations as easy as possible to generate on the computer resources available. Initial conditions for LIS-6 and GEOS-5 are provided by Modern Era Retrospective-Analysis for Research and Applications (MERRA) reanalysis data stored on DISCOVER. The LIS-6 is first run for 2-4 years forced by MERRA atmospheric analyses, generating initial conditions for the WRF soil physics. GEOS-5 is then initialized from MERRA data and run for the period of interest. Large-scale atmospheric data, sea-surface temperatures, and sea ice coverage from GEOS-5 are used as boundary conditions for WRF, which is run for the same period of interest. Multiply nested grids are used for both LIS-6 and WRF, with the innermost grid run at a resolution sufficient for typical

  9. Status and Plans for Reanalysis at NASA/GMAO

    NASA Technical Reports Server (NTRS)

    Gelaro, Ron

    2017-01-01

    Reanalysis plays a critical role in GMAOs goal to enhance NASA's program of Earth observations, providing vital data sets for climate research and the development of future missions. As the breadth of NASAs observations expands to include multiple components of the Earth system, so does the need to assimilate observations from currently uncoupled components of the system in a more physically consistent manner. GMAOs most recent reanalysis of the satellite era, MERRA-2, has completed the period 1980-present, and is now running as a continuing global climate analysis with two- to three-week latency. MERRA-2 assimilates meteorological and aerosol observations as a weakly coupled assimilation system as a first step toward GMAOs longer term goal of developing an integrated Earth system analysis (IESA) capability that will couple assimilation systems for the atmosphere, ocean, land and chemistry. The GMAO strategy is to progress incrementally toward an IESA through an evolving combination of coupled systems and offline component reanalyses driven by, for example, MERRA-2 atmospheric forcing. Most recently, the GMAO has implemented a weakly coupled assimilation scheme for analyzing ocean skin temperature within the existing atmospheric analysis. The scheme uses background fields from a near-surface ocean diurnal layer model to assimilate surface-sensitive radiances plus in-situ observations along with all other observations in the atmospheric assimilation system. In addition, MERRA-2-driven simulations of the ocean (plus sea ice) and atmospheric chemistry (for the EOS period) are currently underway, as is the development of a coupled atmosphere-ocean assimilation system. This talk will describe the status of these ongoing efforts and the planned steps toward an IESA capability for climate research.

  10. NASA IYA Programs

    NASA Astrophysics Data System (ADS)

    Hasan, Hashima; Smith, D.

    2009-05-01

    NASA's Science Mission Directorate (SMD) launched a variety of programs to celebrate the International Year of Astronomy (IYA) 2009. A few examples will be presented to demonstrate how the exciting science generated by NASA's missions in astrophysics, planetary science and heliophysics has been given an IYA2009 flavor and made available to students, educators and the public worldwide. NASA participated in the official kickoff of US IYA activities by giving a sneak preview of a multi-wavelength image of M101, and of other images from NASA's space science missions that are now traveling to 40 public libraries around the country. NASA IYA Student Ambassadors represented the USA at the international Opening Ceremony in Paris, and have made strides in connecting with local communities throughout the USA. NASA's Object of the Month activities have generated great interest in the public through IYA Discovery Guides. Images from NASA's Great Observatories are included in the From Earth to the Universe (FETTU) exhibition, which was inaugurated both in the US and internationally. The Hubble Space Telescope Project had a tremendous response to its 100 Days of Astronomy "You Decide” competition. NASA's IYA programs have started a journey into the world of astronomy by the uninitiated and cultivated the continuation of a quest by those already enraptured by the wonders of the sky.

  11. Joseph Constantine Carpue and the Bicentennial of the Birth of Modern Plastic Surgery.

    PubMed

    Freshwater, M Felix

    2015-08-01

    September 2014 marked the bicentennial of the birth of modern plastic surgery. It was then that Carpue began a prospective observational study of nasal reconstruction that culminated in his 1816 monograph, which caused an explosion of interest in reconstructive surgery throughout Europe. In conducting his study, Carpue demonstrated ethical standards and the power of planning a procedure. His methods to document his results accurately would remain unsurpassed until photography was adopted at the end of the 19th century. Carpue took an apocryphal story of surgery performed in India more than twenty years earlier and transformed it into the beginning of modern plastic surgery. He succeeded in a number of unrecognized tasks that are themselves landmarks not only in plastic surgical history, but surgical history: devising the first prospective observational study, using exclusion criteria, maintaining appropriate patient confidentiality, setting a standard for preoperative disclosure and ethical approval over a century before these measures were codified, having independent documentation of his preoperative and postoperative findings, devising a method to objectively monitor and document the forehead flap, and describing the potential value of tissue expansion. He shared his experience by publishing his results and by lecturing in Europe. His contemporaries recognized him for his contributions and he was honored by election to the Royal Society. Carpue launched the modern era of plastic surgery in an ethical, logical, and objective manner. While plastic surgery has changed in the last two centuries, the principles that Carpue followed remain valid. © 2015 The American Society for Aesthetic Plastic Surgery, Inc.

  12. Community Colleges: Key to Vietnam Era GI Bill Shortfall.

    ERIC Educational Resources Information Center

    Horan, J. Michael

    The Vietnam Era GI Bill was clearly influenced by the social and educational success of World War II veterans, but also reflected the policy objectives of equity and access of the 1960's. A 1987 monograph by the U.S. Department of Veterans Affairs reported that 60% of all Vietnam Era veterans received some training benefit from the GI Bill, but…

  13. Proposed Array-based Deep Space Network for NASA

    NASA Technical Reports Server (NTRS)

    Bagri, Durgadas S.; Statman, Joseph I.; Gatti, Mark S.

    2007-01-01

    The current assets of the Deep Space Network (DSN) of the National Aeronautics and Space Administration (NASA), especially the 70-m antennas, are aging and becoming less reliable. Furthermore, they are expensive to operate and difficult to upgrade for operation at Ka-band (321 GHz). Replacing them with comparable monolithic large antennas would be expensive. On the other hand, implementation of similar high-sensitivity assets can be achieved economically using an array-based architecture, where sensitivity is measured by G/T, the ratio of antenna gain to system temperature. An array-based architecture would also provide flexibility in operations and allow for easy addition of more G/T whenever required. Therefore, an array-based plan of the next-generation DSN for NASA has been proposed. The DSN array would provide more flexible downlink capability compared to the current DSN for robust telemetry, tracking and command services to the space missions of NASA and its international partners in a cost effective way. Instead of using the array as an element of the DSN and relying on the existing concept of operation, we explore a broader departure in establishing a more modern concept of operations to reduce the operations costs. This paper presents the array-based architecture for the next generation DSN. It includes system block diagram, operations philosophy, user's view of operations, operations management, and logistics like maintenance philosophy and anomaly analysis and reporting. To develop the various required technologies and understand the logistics of building the array-based lowcost system, a breadboard array of three antennas has been built. This paper briefly describes the breadboard array system and its performance.

  14. Garver NASA Social

    NASA Image and Video Library

    2011-05-18

    NASA Deputy Administrator Lori Garver, in yellow jacket, stands with participants from the NASA Social underneath the engines of the Saturn V rocket at the Apollo Saturn V visitor center, Thursday, May 18, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

  15. NASA Mission: The Universe

    NASA Technical Reports Server (NTRS)

    1990-01-01

    This booklet is mainly a recruitment tool for the various NASA Centers. This well illustrated booklet briefly describes NASA's mission and career opportunities on the NASA team. NASA field installations and their missions are briefly noted. NASA's four chief program offices are briefly described. They are: (1) Aeronautics, Exploration, and Space Technology; (2) Space Flight; (3) Space Operations; and (4) Space Science and Applications.

  16. NASA Remote Sensing Applications for Archaeology and Cultural Resources Management

    NASA Technical Reports Server (NTRS)

    Giardino, Marco J.

    2008-01-01

    the use of remote sensing. In 2007, NASA awarded six competitively chosen projects in Space Archaeology through an open solicitation whose purpose, among several, was to addresses the potential benefits to modern society that can be derived through a better understanding of how past cultures succeeded or failed to adapt to local, regional, and global change. A further objective of NASA's space archaeology is the protection and preservation of cultural heritage sites while planning for the sustainable development of cultural resources. NASA s archaeological approach through remote sensing builds on traditional methods of aerial archaeology (i.e. crop marks) and utilizes advanced technologies for collecting and analyzing archaeological data from digital imagery. NASA s archaeological research and application projects using remote sensing have been conducted throughout the world. In North America, NASA has imaged prehistoric mound sites in Mississippi; prehistoric shell middens in Louisiana, Puebloan sites in New Mexico and more recently the sites associated with the Lewis and Clark Corps of Discovery Expedition (1804-1806). In Central America, NASA archaeologists have researched Mayan sites throughout the region, including the Yucatan and Costa Rica, as well as Olmec localities in Veracruz. Other data has been collected over Angkor, Cambodia, Giza in Egypt, the lost city of Ubar on the Arabian Peninsula.

  17. NASA low-speed centrifugal compressor for fundamental research

    NASA Technical Reports Server (NTRS)

    Wood, J. R.; Adam, P. W.; Buggele, A. E.

    1983-01-01

    A new centrifugal compressor facility being built by the NASA Lewis Research Center is described; its purpose is to obtain 'benchmark' experimental data for internal flow code verification and modeling. The facility will be heavily instrumented with standard pressure and temperature probes and have provisions for flow visualization and laser Doppler velocimetry. The facility will accommodate rotational speeds to 2400 rpm and will be rated at pressures to 1.25 atm. The initial compressor stage for testing is geometrically and dynamically representative of modern high-performance stages with the exception of Mach number levels. Design exit tip speed for the initial stage is 500 ft/sec with a pressure ratio of 1.17. The rotor exit backsweep is 55 deg from radial. The facility is expected to be operational in the first half of 1985.

  18. Research in NASA History: A Guide to the NASA History Program

    NASA Technical Reports Server (NTRS)

    Garber, Stephen J. (Compiler)

    1997-01-01

    This monograph details the archival and other related resources held by the NASA History Office at Headquarters, and at NASA's Field Centers and other related government agencies. It also gives information on the NASA History publications, World Wide Web pages and the like.

  19. Foundational biomedical informatics research in the clinical and translational science era: a call to action.

    PubMed

    Payne, Philip R O; Embi, Peter J; Niland, Joyce

    2010-01-01

    Advances in clinical and translational science, along with related national-scale policy and funding mechanisms, have provided significant opportunities for the advancement of applied clinical research informatics (CRI) and translational bioinformatics (TBI). Such efforts are primarily oriented to application and infrastructure development and are critical to the conduct of clinical and translational research. However, they often come at the expense of the foundational CRI and TBI research needed to grow these important biomedical informatics subdisciplines and ensure future innovations. In light of this challenge, it is critical that a number of steps be taken, including the conduct of targeted advocacy campaigns, the development of community-accepted research agendas, and the continued creation of forums for collaboration and knowledge exchange. Such efforts are needed to ensure that the biomedical informatics community is able to advance CRI and TBI science in the context of the modern clinical and translational science era.

  20. NASA Overview

    NASA Technical Reports Server (NTRS)

    Sheffner, Edwin J.

    2007-01-01

    The Earth Science Division supports research projects that exploit the observations and measurements acquired by NASA Earth Observing missions and Applied Sciences projects that extend NASA research to the broader user community and address societal needs.

  1. [Case histories and other stories in the multimedia era... but was there something else?...].

    PubMed

    Kohler, Hans-Peter

    2010-12-01

    The multimedia era is fascinating and limitless! The advances in the field of consumer and entertainment electronics are impressive. Our private as well as business life is very much accompanied and influenced by numerous technical gadgets. These advancements should have many positive implications on our clinical work. Do they? Using modern personal computers and clinic information systems (CIS) the access to patients' data, the prescription of drugs, or x-ray diagnostics on high-resolution laptop screens became as easy as pie. This affects the doctor-patient relationship but also the communication between physicians and nurses. Computers also affect our daily clinical work and therefore the treatment of our patients. Do our patients take benefit from these technical achievements? Does the use of clinic information systems positively influence diagnosis, treatment and finally patient outcome but also doctors' performances? What has really changed in the last couples of years? The present article tries to critically review these major changes in patient care.

  2. Modeling the Earth system in the Mission to Planet Earth era

    NASA Technical Reports Server (NTRS)

    Unninayar, Sushel; Bergman, Kenneth H.

    1993-01-01

    A broad overview is made of global earth system modeling in the Mission to Planet Earth (MTPE) era for the multidisciplinary audience encompassed by the Global Change Research Program (GCRP). Time scales of global system fluctuation and change are described in Section 2. Section 3 provides a rubric for modeling the global earth system, as presently understood. The ability of models to predict the future state of the global earth system and the extent to which their predictions are reliable are covered in Sections 4 and 5. The 'engineering' use of global system models (and predictions) is covered in Section 6. Section 7 covers aspects of an increasing need for improved transform algorithms and better methods to assimilate this information into global models. Future monitoring and data requirements are detailed in Section 8. Section 9 covers the NASA-initiated concept 'Mission to Planet Earth,' which employs space and ground based measurement systems to provide the scientific basis for understanding global change. Section 10 concludes this review with general remarks concerning the state of global system modeling and observing technology and the need for future research.

  3. Patient-Centered Communication: Exploring the Dentist's Role in the Era of e-Patients and Health 2.0.

    PubMed

    Seymour, Brittany; Yang, Helen; Getman, Rebekah; Barrow, Jane; Kalenderian, Elsbeth

    2016-06-01

    In today's digital era, people are increasingly relying on the Internet-including social media-to access health information and inform their health decisions. This article describes an exploratory initiative to better understand and define the role of dentists in patient education in the context of e-patients and Health 2.0. This initiative consisted of four phases. In Phase I, an interdisciplinary expert advisory committee was assembled for a roundtable discussion about patients' health information-seeking behaviors online. In Phase II, a pilot case study was conducted, with methods and analysis informed by Phase I recommendations. Phase III consisted of a debriefing conference to outline future areas of research on modernizing health communication strategies. In Phase IV, the findings and working theories were presented to 75 dental students, who then took a survey regarding their perspectives with the objective of guiding potential curriculum design for predoctoral courses. The results of the survey showed that the validity of online content was often secondary to the strength of the network sharing it and that advocacy online could be more effective if it allowed for emotional connections with peers rather than preserving accuracy of the information. Students expressed high interest in learning how to harness modern health communications in their clinical care since the role of the dentist is evolving from giving information to giving personalized guidance against the backdrop of an often contradictory modern information environment. The authors recommend that the dental profession develop patient-centered health communication training for predoctoral students and professional development and continuing education for practicing professionals.

  4. Technology: A New Era in Education

    ERIC Educational Resources Information Center

    Cunningham, William G.

    1977-01-01

    Teachers and technologists have lived apart, with much doubt on both sides. The author suggests that collaboration, mutual trust, and respect, will usher in a new era for effective education. (Editor)

  5. Growth of semimetallic ErAs films epitaxially embedded in GaAs

    NASA Astrophysics Data System (ADS)

    Crook, Adam M.; Nair, Hari P.; Lee, Jong H.; Ferrer, Domingo A.; Akinwande, Deji; Bank, Seth R.

    2011-10-01

    We present models for the growth and electrical conductivity of ErAs films grown with the nanoparticle-seeded film growth technique. This growth mode overcomes the mismatch in rotational symmetry between the rocksalt ErAs crystal structure and the zincblende GaAs crystal structure. This results in films of ErAs grown through a thin film of GaAs that preserves the symmetry of the substrate. The conductivity of the films, as a function of film thickness, are investigated and a surface roughness model is used to explain observed trends. Transmission electron micrographs confirm the suppression of anti-phase domains. A simple diffusion model is developed to describe the diffusion and incorporation of surface erbium into subsurface ErAs layers and predict potential failure mechanisms of the growth method.

  6. Langley Centennial Celebration Highlights Hidden Figures on This Week @NASA – December 2, 2016

    NASA Image and Video Library

    2016-12-02

    On Dec. 1, NASA Administrator Charlie Bolden helped kick off a yearlong centennial celebration for the agency’s Langley Research Center in Hampton, Virginia with several events highlighting the work of the African American women of Langley’s West Computing Unit. These mathematicians performed critical calculations for several historic NASA space missions in the early days of America’s space program, and their story is told in the book, “Hidden Figures,” by author Margot Lee Shetterly and the upcoming 20th Century Fox movie of the same name. It was also discussed during a NASA education event at Langley featuring Bolden, the film’s director Ted Melfi, NASA’s Chief Historian Bill Barry, and Langley electro-optics engineer Julie Williams-Byrd – a modern-day NASA figure using science, technology, engineering and mathematics, or STEM -- skills to make an impact. Later that evening, a VIP social and screenings of the film took place at nearby Virginia Air & Space Center. The women featured in Hidden Figures – Katherine Johnson, Mary Jackson and Dorothy Vaughan – known as “human computers,” helped put John Glenn in orbit, and helped Neil Armstrong and other astronauts land on the moon. Also, Cassini’s Ring-Grazing Orbit around Saturn, Next Space Station Crew Previews Mission, and Russian Cargo Ship Experiences Anomaly after Launch!

  7. Japan’s Role in the New Era

    DTIC Science & Technology

    1992-04-15

    JAPAN’S ROLE IN THE NEW ERA BY .1 Colonel Yasuhiro Naomi ELECTE .F Japan Ground Self Defense Force ,4aY 1.4 19,92 A DISTRIBUTION STATEMENT A: Approved...Colonel Yasuhiro Naomi D.ti ibltof Japan Ground Self Defense Force ,v’ilti~ity Cod - A~a~i ardj r Colonel Donald W. Boose, Jr...Pennsylvania 17013 ABSTRACT AUTHOR: Colonel Yasuhiro Naomi, Japan Ground Self -Defense Force TITLE: Japan’s Role in the New Era FORMAT: Individual Study

  8. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Interior of a Biotechnology Refrigerator that preserves samples for use in (or after culturing in) the NASA Bioreactor. The unit is shown extracted from a middeck locker shell. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  9. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Biotechnology Refrigerator that preserves samples for use in (or after culturing in) the NASA Bioreactor. The unit is shown extracted from a middeck locker shell. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  10. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Biotechnology Refrigerator that preserves samples for use in (or after culturing in) the NASA Bioreactor. The unit is shown extracted from a middeck locker shell and with thermal blankets partially removed. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  11. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Laptop computer sits atop the Experiment Control Computer for a NASA Bioreactor. The flight crew can change operating conditions in the Bioreactor by using the graphical interface on the laptop. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  12. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Close-up view of the interior of a NASA Bioreactor shows the plastic plumbing and valves (cylinders at right center) to control fluid flow. The rotating wall vessel is at top center. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  13. NASA Langley and NLR Research of Distributed Air/Ground Traffic Management

    NASA Technical Reports Server (NTRS)

    Ballin, Mark G.; Hoekstra, Jacco M.; Wing, David J.; Lohr, Gary W.

    2002-01-01

    Distributed Air/Ground Traffic Management (DAG-TM) is a concept of future air traffic operations that proposes to distribute information, decision-making authority, and responsibility among flight crews, the air traffic service provider, and aeronautical operational control organizations. This paper provides an overview and status of DAG-TM research at NASA Langley Research Center and the National Aerospace Laboratory of The Netherlands. Specific objectives of the research are to evaluate the technical and operational feasibility of the autonomous airborne component of DAG-TM, which is founded on the operational paradigm of free flight. The paper includes an overview of research approaches, the airborne technologies under development, and a summary of experimental investigations and findings to date. Although research is not yet complete, these findings indicate that free flight is feasible and will significantly enhance system capacity and safety. While free flight cannot alone resolve the complex issues faced by those modernizing the global airspace, it should be considered an essential part of a comprehensive air traffic management modernization activity.

  14. NASA Future Forum

    NASA Image and Video Library

    2011-08-11

    Leland Melvin, NASA Associate Administrator for Education, speaks during a panel discussion on inspiration in education at the 2011 NASA Future Forum held at the Riggs Alumni Center on the campus of the University of Maryland, Thursday, Aug. 11, 2011, in College Park, Md. Photo Credit: (NASA/Paul E. Alers)

  15. Selling to NASA

    NASA Technical Reports Server (NTRS)

    1986-01-01

    Prospective contractors are acquainted with the organizational structure of NASA, and the major technical program offices and selected staff offices at the Headquarters level are briefly described. The basic procedures for Federal procurement are covered. A primer is presented on how to market to NASA. While the information is specific to NASA, many of the principles are applicable to other agencies as well. Some of the major programs are introduced which are available to small and disadvantaged businesses. The major research programs and fields of interest at individual NASA centers are summarized.

  16. NASA Future Forum

    NASA Image and Video Library

    2012-02-21

    Fayette Collier, Aeronautics Research Mission Directorate, NASA Headquarters talks during the NASA Future Forum panel titled "Transferring and Commercializing Technology to Benefit Our Lives and Our Economy" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

  17. NASA Future Forum

    NASA Image and Video Library

    2012-02-21

    NASA Technology Transfer Program Executive Daniel Lockney moderates the NASA Future Forum panel titled "Transferring and Commercializing Technology to Benefit Our Lives and Our Economy" at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

  18. NASA Turbulence Technologies In-Service Evaluation: Delta Air Lines Report-Out

    NASA Technical Reports Server (NTRS)

    Amaral, Christian; Dickson, Steve; Watts, Bill

    2007-01-01

    Concluding an in-service evaluation of two new turbulence detection technologies developed in the Turbulence Prediction and Warning Systems (TPAWS) element of the NASA Aviation Safety and Security Program's Weather Accident Prevention Project (WxAP), this report documents Delta's experience working with the technologies, feedback gained from pilots and dispatchers concerning current turbulence techniques and procedures, and Delta's recommendations regarding directions for further efforts by the research community. Technologies evaluated included an automatic airborne turbulence encounter reporting technology called the Turbulence Auto PIREP System (TAPS), and a significant enhancement to the ability of modern airborne weather radars to predict and display turbulence of operational significance, called E-Turb radar.

  19. NASA Webb Telescope

    NASA Image and Video Library

    2017-12-08

    NASA image release September 17, 2010 In preparation for a cryogenic test NASA Goddard technicians install instrument mass simulators onto the James Webb Space Telescope ISIM structure. The ISIM Structure supports and holds the four Webb telescope science instruments : the Mid-Infrared Instrument (MIRI), the Near-Infrared Camera (NIRCam), the Near-Infrared Spectrograph (NIRSpec) and the Fine Guidance Sensor (FGS). Credit: NASA/GSFC/Chris Gunn To learn more about the James Webb Space Telescope go to: www.jwst.nasa.gov/ NASA Goddard Space Flight Center contributes to NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s endeavors by providing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

  20. NASA SAVE Award Winner

    NASA Image and Video Library

    2012-01-09

    NASA Goddard Space Flight Center Financial Manager and White House 2011 SAVE award winner Matthew Ritsko is seen during a television interview at NASA Headquarters shortly after meeting with President Obama at the White House on Monday, Jan. 9, 2011, in Washington. The Presidential Securing Americans' Value and Efficiency (SAVE) program gives front-line federal workers the chance to submit their ideas on how their agencies can save money and work more efficiently. Matthew's proposal calls for NASA to create a "lending library" where specialized space tools and hardware purchased by one NASA organization will be made available to other NASA programs and projects. Photo Credit: (NASA/Bill Ingalls)

  1. Development of an Outreach Program for NASA: "NASA Ambassadors"

    NASA Technical Reports Server (NTRS)

    Lebo, George

    1998-01-01

    The NASA Ambassadors Program is designed to present the excitement and importance of NASA's programs to its customers, the general public. Those customers, which are identified in the "Science Communications Strategy" developed by the Space Sciences Laboratory at the MSFC, are divided into three categories: (1) Not interested and not knowledgeable; (2) Interested but not knowledgeable; and (3) Science attentive. In it they recognize that it makes the most sense to attempt to communicate with those described in the last two categories. However, their plan suggests that the media and the educational institutions are the only means of outreach. The NASA Ambassadors Program allows NASA to reach its target audience directly. Steps to be taken in order for the program to commence: (1) MSFC chooses to support the NASA Ambassadors Program - decision point; (2) Designate an "Office In Charge". (3) Assign the "Operation" phase to in-house MSFC personnel or to a contractor - decision point; (4) Name a point of contact; (5) Identify partners in the program and enlist their assistance; (6) Process an unsolicited proposal from an outside source to accomplish those tasks which MSFC chooses to out-source.

  2. NASA specification for manufacturing and performance requirements of NASA standard aerospace nickel-cadmium cells

    NASA Technical Reports Server (NTRS)

    1988-01-01

    On November 25, 1985, the NASA Chief Engineer established a NASA-wide policy to maintain and to require the use of the NASA standard for aerospace nickel-cadmium cells and batteries. The Associate Administrator for Safety, Reliability, Maintainability, and Quality Assurance stated on December 29, 1986, the intent to retain the NASA standard cell usage policy established by the Office of the Chief Engineer. The current NASA policy is also to incorporate technological advances as they are tested and proven for spaceflight applications. This policy will be implemented by modifying the existing standard cells or by developing new NASA standards and their specifications in accordance with the NASA's Aerospace Battery Systems Program Plan. This NASA Specification for Manufacturing and Performance Requirements of NASA Standard Aerospace Nickel-Cadmium Cells is prepared to provide requirements for the NASA standard nickel-cadmium cell. It is an interim specification pending resolution of the separator material availability. This specification has evolved from over 15 years of nickel-cadmium cell experience by NASA. Consequently, considerable experience has been collected and cell performance has been well characterized from many years of ground testing and from in-flight operations in both geosynchronous (GEO) and low earth orbit (LEO) applications. NASA has developed and successfully used two standard flight qualified cell designs.

  3. NASA Team Looks to Ancient Earth First to Study Hazy Exoplanets

    NASA Image and Video Library

    2017-12-08

    “We like to say that Archean Earth is the most alien planet we have geochemical data for,” For astronomers trying to understand which distant planets might have habitable conditions, the role of atmospheric haze has been hazy. To help sort it out, a team of researchers has been looking to Earth – specifically Earth during the Archean era, an epic 1-1/2-billion-year period early in our planet’s history. Read more: go.nasa.gov/2kTBhPU Caption: When haze built up in the atmosphere of Archean Earth, the young planet might have looked like this artist's interpretation - a pale orange dot. A team led by Goddard scientists thinks the haze was self-limiting, cooling the surface by about 36 degrees Fahrenheit (20 Kelvins) – not enough to cause runaway glaciation. The team’s modeling suggests that atmospheric haze might be helpful for identifying earthlike exoplanets that could be habitable. Credits: NASA’s Goddard Space Flight Center/Francis Reddy

  4. The Physical State of the Universe in the Planck Era

    NASA Astrophysics Data System (ADS)

    Riggs, Peter J.

    2018-06-01

    The Planck Era cannot be given an accurate mathematical description until the full theory of quantum gravity is available. However, some aspects of the physical state of the Planck Era can be revealed by order of the magnitude considerations which also have implications for the low entropy of the very early universe.

  5. NASA reports

    NASA Technical Reports Server (NTRS)

    Obrien, John E.; Fisk, Lennard A.; Aldrich, Arnold A.; Utsman, Thomas E.; Griffin, Michael D.; Cohen, Aaron

    1992-01-01

    Activities and National Aeronautics and Space Administration (NASA) programs, both ongoing and planned, are described by NASA administrative personnel from the offices of Space Science and Applications, Space Systems Development, Space Flight, Exploration, and from the Johnson Space Center. NASA's multi-year strategic plan, called Vision 21, is also discussed. It proposes to use the unique perspective of space to better understand Earth. Among the NASA programs mentioned are the Magellan to Venus and Galileo to Jupiter spacecraft, the Cosmic Background Explorer, Pegsat (the first Pegasus payload), Hubble, the Joint U.S./German ROSAT X-ray Mission, Ulysses to Jupiter and over the sun, the Astro-Spacelab Mission, and the Gamma Ray Observatory. Copies of viewgraphs that illustrate some of these missions, and others, are provided. Also discussed were life science research plans, economic factors as they relate to space missions, and the outlook for international cooperation.

  6. NASA reports

    NASA Astrophysics Data System (ADS)

    Obrien, John E.; Fisk, Lennard A.; Aldrich, Arnold A.; Utsman, Thomas E.; Griffin, Michael D.; Cohen, Aaron

    Activities and National Aeronautics and Space Administration (NASA) programs, both ongoing and planned, are described by NASA administrative personnel from the offices of Space Science and Applications, Space Systems Development, Space Flight, Exploration, and from the Johnson Space Center. NASA's multi-year strategic plan, called Vision 21, is also discussed. It proposes to use the unique perspective of space to better understand Earth. Among the NASA programs mentioned are the Magellan to Venus and Galileo to Jupiter spacecraft, the Cosmic Background Explorer, Pegsat (the first Pegasus payload), Hubble, the Joint U.S./German ROSAT X-ray Mission, Ulysses to Jupiter and over the sun, the Astro-Spacelab Mission, and the Gamma Ray Observatory. Copies of viewgraphs that illustrate some of these missions, and others, are provided. Also discussed were life science research plans, economic factors as they relate to space missions, and the outlook for international cooperation.

  7. NASA Earth Day 2014

    NASA Image and Video Library

    2014-04-22

    NASA Administrator Charles Bolden speaks to students who attended the NASA sponsored Earth Day event April 22, 2014 at Union Station in Washington, DC. NASA sponsored the Earth Day event as part of its "Earth Right Now" campaign, celebrating the launch of five Earth-observing missions in 2014. Photo Credit: (NASA/Aubrey Gemignani)

  8. NASA Columbus Future Forum

    NASA Image and Video Library

    2012-02-20

    Leland Melvin, NASA Associate Administrator for Education and NASA Astronaut, moderates the NASA Future Forum Inspiration and Education Panel at The Ohio State University on Monday, Feb. 20, 2012, in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

  9. NASA's program on icing research and technology

    NASA Technical Reports Server (NTRS)

    Reinmann, John J.; Shaw, Robert J.; Ranaudo, Richard J.

    1989-01-01

    NASA's program in aircraft icing research and technology is reviewed. The program relies heavily on computer codes and modern applied physics technology in seeking icing solutions on a finer scale than those offered in earlier programs. Three major goals of this program are to offer new approaches to ice protection, to improve our ability to model the response of an aircraft to an icing encounter, and to provide improved techniques and facilities for ground and flight testing. This paper reviews the following program elements: (1) new approaches to ice protection; (2) numerical codes for deicer analysis; (3) measurement and prediction of ice accretion and its effect on aircraft and aircraft components; (4) special wind tunnel test techniques for rotorcraft icing; (5) improvements of icing wind tunnels and research aircraft; (6) ground de-icing fluids used in winter operation; (7) fundamental studies in icing; and (8) droplet sizing instruments for icing clouds.

  10. NASA's Space Launch System Transitions From Design To Production

    NASA Technical Reports Server (NTRS)

    Askins, Bruce R.; Robinson, Kimberly F.

    2016-01-01

    NASA's Space Launch System (SLS) successfully completed its Critical Design Review (CDR) in 2015, a major milestone on the journey to an unprecedented era of exploration for humanity. CDR formally marked the program's transition from design to production phase just four years after the program's inception and the first such milestone for a human launch vehicle in 40 years. While challenges typical of a complex development program lie ahead, CDR evaluators concluded that the design is technically and programmatically sound and ready to press forward to Design Certification Review (DCR) and readiness for launch of Exploration Mission 1 (EM-1) in the 2018 timeframe. SLS is prudently based on existing propulsion systems, infrastructure and knowledge with a clear, evolutionary path as required by mission needs. In its initial configuration, designated Block 1, SLS will a minimum of 70 metric tons (t) (154,324 pounds) of payload to low Earth orbit (LEO). It will evolve to a 130 t (286,601 pound) payload capacity by upgrading its engines, boosters, and upper stage, dramatically increasing the mass and volume of human and robotic exploration while decreasing mission risk, increasing safety, and simplifying ground and mission operations. CDR was the central programmatic accomplishment among many technical accomplishments that will be described in this paper. The government/industry SLS team successfully test-fired a flight-like five-segment solid rocket motor, as well as seven hotfire development tests of the RS-25 core stage engine. The majority of the major test article and flight barrels, rings, and domes for the core stage liquid oxygen, liquid hydrogen, engine section, intertank, and forward skirt were manufactured at NASA's Michoud Assembly Facility in New Orleans, Louisiana. Renovations to the B-2 test stand for stage green run testing were completed at NASA's Stennis Space Center (SSC), near Bay St. Louis, Mississippi. Core stage test stands are reaching completion

  11. LADEE NASA Social

    NASA Image and Video Library

    2013-09-05

    A participant at a NASA Social on the Lunar Atmosphere and Dust Environment Explorer (LADEE) mission asks a question, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

  12. TDRS-M NASA Social

    NASA Image and Video Library

    2017-08-17

    Social media gather in Kennedy Space Center’s Press Site auditorium for a briefing focused on preparations to launch NASA's Tracking and Data Relay Satellite, TDRS-M. The latest spacecraft destined for the agency's constellation of communications satellites, TDRS-M will allow nearly continuous contact with orbiting spacecraft ranging from the International Space Station and Hubble Space Telescope to the array of scientific observatories. Liftoff atop a United Launch Alliance Atlas V rocket is scheduled to take place from Space Launch Complex 41 at Cape Canaveral Air Force Station at 8:03 a.m. EDT Aug. 18. NASA Social Media Team includes: Emily Furfaro and Amber Jacobson. Guest speakers include: Badri Younes, Deputy Associate Administrator for Space Communications and Navigation at NASA Headquarters in Washington; Dave Littmann, Project Manager for TDRS-M at NASA’s Goddard Space Flight Center; Neil Mallik, NASA Deputy Network Director for Human Spaceflight; Nicole Mann, NASA Astronaut; Steve Bowen, NASA Astronaut; Skip Owen, NASA Launch Services; Scott Messer, United Launch Alliance Program Manager for NASA Missions.

  13. Considerations for Using Hybrid Ensemble-Variational Data Assimilation in NASA-GMAO's Next Reanalysis System

    NASA Technical Reports Server (NTRS)

    El Akkraoui, Amal; Todling, Ricardo

    2017-01-01

    The Modern-Era Retrospective Analysis for Research and Applications, version 2 (MERRA-2) is the latest reanalysis produced by GMAO, and provides global data spanning the period 1980-present. The atmospheric data assimilation component of MERRA-2 used a 3D-Var scheme, which was operational at the time of its design. Since then, a Hybrid 3D-Var, then a Hybrid 4D-EnVar were implemented, adding an ensemble component to the data assimilation scheme. In this work, we will be examining the benefits of using hybrid ensemble flow-dependent covariances to represent errors and uncertainties in historic periods. Specifically, periods of pre- and post-satellites, as well as periods of active tropical cyclone seasons. Finally, we will also be exploring the use of adaptive localization scales.

  14. Cassini NASA Social

    NASA Image and Video Library

    2017-09-14

    Nechnical producer for NASA's Eyes at JPL, Jason Craig discusses the Cassini mission as seen through the NASA Eyes program during a NASA Social, Thursday, Sept. 14, 2017 at NASA's Jet Propulsion Laboratory in Pasadena, California. Since its arrival in 2004, the Cassini-Huygens mission has been a discovery machine, revolutionizing our knowledge of the Saturn system and captivating us with data and images never before obtained with such detail and clarity. On Sept. 15, 2017, operators will deliberately plunge the spacecraft into Saturn, as Cassini gathered science until the end. The “plunge” ensures Saturn’s moons will remain pristine for future exploration. During Cassini’s final days, mission team members from all around the world gathered at NASA’s Jet Propulsion Laboratory, Pasadena, California, to celebrate the achievements of this historic mission. Photo Credit: (NASA/Joel Kowsky)

  15. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Exterior view of the NASA Bioreactor Engineering Development Unit flown on Mir. The rotating wall vessel is behind the window on the face of the large module. Control electronics are in the module at left; gas supply and cooling fans are in the module at back. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  16. Dialogue on Modernity and Modern Education in Dispute

    ERIC Educational Resources Information Center

    Baker, Michael; Peters, Michael A.

    2012-01-01

    This is a dialogue or conversation between Michael Baker (MB) and Michael A. Peters (MP) on the concept of modernity and its significance for educational theory. The dialogue took place originally as a conversation about a symposium on modernity held at the American Educational Studies Association meeting 2010. It was later developed for…

  17. NASA's Space Launch System Marks Critical Design Review

    NASA Technical Reports Server (NTRS)

    Singer, Chris

    2016-01-01

    With completion of its Critical Design Review (CDR) in 2015, NASA is deep into the manufacturing and testing phases of its new Space Launch System (SLS) for beyond-Earth exploration. This CDR was the first in almost 40 years for a NASA human launch vehicle and marked another successful milestone on the road to the launch of a new era of deep space exploration. The review marked the 90-percent design-complete, a final look at the design and development plan of the integrated vehicle before full-scale fabrications begins and the prelude to the next milestone, design certification. Specifically, the review looked at the first of three increasingly capable configurations planned for SLS. This "Block I" design will stand 98.2 meters (m) (322 feet) tall and provide 39.1 million Newtons (8.8 million pounds) of thrust at liftoff to lift a payload of approximately 70 metric tons (154,000 pounds). This payload is more than double that of the retired space shuttle program or other current launch vehicles. It dramatically increases the mass and volume of human and robotic exploration. Additionally, it will decrease overall mission risk, increase safety, and simplify ground and mission operations - all significant considerations for crewed missions and unique, high-value national payloads. The Block 1 SLS will launch NASA's Orion Multi-Purpose Crew Vehicle (MPCV) on an uncrewed flight beyond the moon and back and the first crewed flight around the moon. The current design has a direct evolutionary path to a vehicle with a 130t lift capability that offers even more flexibility to reduce planetary trip times, simplify payload design cycles, and provide new capabilities such as planetary sample returns. Every major element of SLS has hardware in production or testing, including flight hardware for the Exploration 1 (EM-1) test flight. In fact, the SLS MPCV-to-Stage-Adapter (MSA) flew successfully on the Exploration Flight Test (EFT) 1 launch of a Delta IV and Orion spacecraft in

  18. NASA Education Stakeholder's Summit

    NASA Image and Video Library

    2010-09-12

    William Kelly, PhD, PE, Manager, Public Affairs, American Society for Engineering Education speaks at the NASA Education Stakeholders’ Summit One Stop Shopping Initiative (OSSI), Monday, Sep. 13, 2010, at the Westfields Marriott Conference Center in Chantilly, VA. Seated are NASA Administrator Charles Bolden, left, and NASA Acting Associate Administrator for Education, James Stofan. (Photo Credit: NASA/Carla Cioffi)

  19. A Rapid Protoyping Approach for the Evaluation of Potential GPM-Era Precipitation Products for Water Resources Management Applications

    NASA Astrophysics Data System (ADS)

    Anantharaj, V. G.; Houser, P. R.; Turk, F. J.; Peterson, C. A.; Hossain, F.; Moorhead, R. J.; Toll, D. L.; Mostovoy, G.

    2009-04-01

    societal benefits related to human health (soil moisture, climate and disease outbreak), homeland security (removal of chemical/biological/nuclear agents), flooding potential and warning, water availability, water quality, and agriculture and food security. In 2006, the NASA ASP sponsored two RPC experiments to evaluate potential GPM-era high resolution satellite precipitation products for water management applications. One of the current uncertainties involved in the GPM missions is the nature of the exact configuration of the constellations of satellites and hence the potential for the dynamic error characteristics over time of the precipitation estimates. For the RPC evaluations, we needed a satellite precipitation product that would be analogous to the GPM-era products. Our solution was to develop a suite of high resolution precipitation products, based on the NRL-Blend algorithm. We created a set of 10 different satellite precipitation estimates (hereafter referred to as the "GPM-proxy data"), using the currently available IR and microwave sensors. However, in each product we systematically left out sets of observations and/or sensors, such as AM orbits. The geographical focus of our study was the operational domain of the Arkansas Basin River Forecast Center (ABRFC) of the U.S. National Weather Service. We have evaluated the GPM-proxy data against the operational product (radar and gauge based) used by ABRFC. Further, we also performed a set of soil water content (SWC) sensitivity experiments using the Noah and Mosaic Land Surface Models (LSM) to quantify the impacts on water management applications involving land surface hydrology. Both the LSMs were forced with the same set of GPM-proxy data. Though the overall spatial patterns for both the models were similar, there were subtle differences in the respective model sensitivities to the different precipitation forcings. These experimental results illustrate the need for comprehensive pre-evaluations of applications

  20. History at NASA

    NASA Technical Reports Server (NTRS)

    1986-01-01

    The efforts of the National Aeronautics and Space Administration to capture and record the events of the past are described, particularly the research accomplishments of NASA's agency-wide history program. A concise guide to the historical research resources available at NASA Headquarters in Washington, D.C., at NASA facilities around the country, and through the federal records systems is given.

  1. Looking Back, Moving Forward: How the Civil Rights Era Church Can Guide the Modern Black Church in Improving Black Student Achievement

    ERIC Educational Resources Information Center

    Gaines, Robert W., II

    2010-01-01

    As the operational center of the Civil Rights Movement, the Black church fostered community, functioned as an educative space, and promoted collaborative efforts among churches. Similarly, the modern Black church has the opportunity to invest in educating, organizing, and mobilizing people within the church and the local community. By investing in…

  2. Energy Exchange NASA Opening Plenary

    NASA Technical Reports Server (NTRS)

    Marrs, Rick

    2017-01-01

    Rick Marrs, Deputy Assistant Administrator Office of Strategic Infrastructure NASA Headquarters will be speaking during the 2017 Energy Exchange opening plenary. His presentation showcases the NASA mission, sustainability at NASA, NASA's strategic Sustainability Performance Plan, Existing PV Partnerships, and NASA funded Solar Initiatives at KSC.

  3. The Science@NASA Websites

    NASA Technical Reports Server (NTRS)

    Koczor, Ronald J.; Phillips. Tony; Rose, M. Franklin (Technical Monitor)

    2000-01-01

    The Science@NASA websites represent a significant stride forward in communicating NASA science to the general public via the Internet. Using a family of websites aimed at science-attentive adults, high school students, middle school students and educators, the Science@NASA activity presents selected stories of on-going NASA science, giving context to otherwise dry press releases and scientific reports.

  4. NASA Performance Report

    NASA Technical Reports Server (NTRS)

    2000-01-01

    Introduction NASA's mission is to advance and communicate scientific knowledge and understanding of Earth, the solar system, and the universe; to advance human exploration, use, and development of space; and to research, develop, verify, and transfer advanced aeronautics, space, and related technologies. In support of this mission, NASA has a strategic architecture that consists of four Enterprises supported by four Crosscutting Processes. The Strategic Enterprises are NASA's primary mission areas to include Earth Science, Space Science, Human Exploration and Development of Space, and Aerospace Technology. NASA's Crosscutting Processes are Manage Strategically, Provide Aerospace Products and Capabilities, Generate Knowledge and Communicate Knowledge. The implementation of NASA programs, science, and technology research occurs primarily at our Centers. NASA consists of a Headquarters, nine Centers, and the Jet Propulsion Laboratory, as well as several ancillary installations and offices in the United States and abroad. The nine Centers are as follows: (1) Ames Research Center, (2) Dryden Flight Research Center (DFRC), (3) Glenn Research Center (GRC), (4) Goddard Space Flight Center (GSFC), (5) Johnson Space Center, (6) Kennedy Space Center (KSC), (7) Langley Research Center (LaRC), (8) Marshall Space Flight Center (MSFC), and (9) Stennis Space Center (SSC).

  5. Viral vaccines and their manufacturing cell substrates: New trends and designs in modern vaccinology.

    PubMed

    Rodrigues, Ana F; Soares, Hugo R; Guerreiro, Miguel R; Alves, Paula M; Coroadinha, Ana S

    2015-09-01

    Vaccination is one of the most effective interventions in global health. The worldwide vaccination programs significantly reduced the number of deaths caused by infectious agents. A successful example was the eradication of smallpox in 1979 after two centuries of vaccination campaigns. Since the first variolation administrations until today, the knowledge on immunology has increased substantially. This knowledge combined with the introduction of cell culture and DNA recombinant technologies revolutionized vaccine design. This review will focus on vaccines against human viral pathogens, recent developments on vaccine design and cell substrates used for their manufacture. While the production of attenuated and inactivated vaccines requires the use of the respective permissible cell substrates, the production of recombinant antigens, virus-like particles, vectored vaccines and chimeric vaccines requires the use - and often the development - of specific cell lines. Indeed, the development of novel modern viral vaccine designs combined with, the stringent safety requirements for manufacture, and the better understanding on animal cell metabolism and physiology are increasing the awareness on the importance of cell line development and engineering areas. A new era of modern vaccinology is arriving, offering an extensive toolbox to materialize novel and creative ideas in vaccine design and its manufacture. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Langley Research Center's Unitary Plan Wind Tunnel: Testing Capabilities and Recent Modernization Activities

    NASA Technical Reports Server (NTRS)

    Micol, John R.

    2001-01-01

    Description, capabilities, initiatives, and utilization of the NASA Langley Research Center's Unitary Plan Wind Tunnel are presented. A brief overview of the facility's operational capabilities and testing techniques is provided. A recent Construction of Facilities (CoF) project to improve facility productivity and efficiency through facility automation has been completed and is discussed. Several new and maturing thrusts are underway that include systematic efforts to provide credible assessment for data quality, modifications to the new automation control system for increased compatibility with the Modern Design Of Experiments (MDOE) testing methodology, and process improvements for better test coordination, planning, and execution.

  7. Langley Research Center's Unitary Plan Wind Tunnel: Testing Capabilities and Recent Modernization Activities

    NASA Technical Reports Server (NTRS)

    Micol, John R.

    2001-01-01

    Description, capabilities, initiatives, and utilization of the NASA Langley Research Center's Unitary Plan Wind Tunnel are presented. A brief overview of the facility's operational capabilities and testing techniques is provided. A recent Construction of Facilities (Car) project to improve facility productivity and efficiency through facility automation has been completed and is discussed. Several new and maturing thrusts are underway that include systematic efforts to provide credible assessment for data quality, modifications to the new automation control system for increased compatibility with the Modern Design of Experiments (MDOE) testing methodology, and process improvements for better test coordination, planning, and execution.

  8. NASA Pocket Statistics

    NASA Technical Reports Server (NTRS)

    1994-01-01

    Pocket Statistics is published for the use of NASA managers and their staff. Included herein is Administrative and Organizational information, summaries of Space Flight Activity including the NASA Major Launch Record, and NASA Procurement, Financial, and Manpower data. The NASA Major Launch Record includes all launches of Scout class and larger vehicles. Vehicle and spacecraft development flights are also included in the Major Launch Record. Shuttle missions are counted as one launch and one payload, where free flying payloads are not involved. Satellites deployed from the cargo bay of the Shuttle and placed in a separate orbit or trajectory are counted as an additional payload.

  9. NASA New England Outreach Center

    NASA Technical Reports Server (NTRS)

    2002-01-01

    The NASA New England Outreach Center in Nashua, New Hampshire was established to serve as a catalyst for heightening regional business awareness of NASA procurement, technology and commercialization opportunities. Emphasis is placed on small business participation, with the highest priority given to small disadvantaged businesses, women-owned businesses, HUBZone businesses, service disabled veteran owned businesses, and historically black colleges and universities and minority institutions. The Center assists firms and organizations to understand NASA requirements and to develop strategies to capture NASA related procurement and technology opportunities. The establishment of the NASA Outreach Center serves to stimulate business in a historically underserved area. NASA direct business awards have traditionally been highly present in the West, Midwest, South, and Southeast areas of the United States. The Center guides and assists businesses and organizations in the northeast to target opportunities within NASA and its prime contractors and capture business and technology opportunities. The Center employs an array of technology access, one-on-one meetings, seminars, site visits, and targeted conferences to acquaint Northeast firms and organizations with representatives from NASA and its prime contractors to learn about and discuss opportunities to do business and access the inventory of NASA technology. This stimulus of interaction also provides firms and organizations the opportunity to propose the use of their developed technology and ideas for current and future requirements at NASA. The Center provides a complement to the NASA Northeast Regional Technology Transfer Center in developing prospects for commercialization of NASA technology. In addition, the Center responds to local requests for assistance and NASA material and documents, and is available to address immediate concerns and needs in assessing opportunities, timely support to interact with NASA Centers on

  10. NASA's educational programs

    NASA Technical Reports Server (NTRS)

    Brown, Robert W.

    1990-01-01

    The educational programs of NASA's Educational Affairs Division are examined. The problem of declining numbers of science and engineering students is reviewed. The various NASA educational programs are described, including programs at the elementary and secondary school levels, teacher education programs, and undergraduate, graduate, and university faculty programs. The coordination of aerospace education activities and future plans for increasing NASA educational programs are considered.

  11. Singular F(R) cosmology unifying early- and late-time acceleration with matter and radiation domination era

    NASA Astrophysics Data System (ADS)

    Odintsov, S. D.; Oikonomou, V. K.

    2016-06-01

    We present some cosmological models which unify the late- and early-time acceleration eras with the radiation and the matter domination era, and we realize the cosmological models by using the theoretical framework of F(R) gravity. Particularly, the first model unifies the late- and early-time acceleration with the matter domination era, and the second model unifies all the evolution eras of our Universe. The two models are described in the same way at early and late times, and only the intermediate stages of the evolution have some differences. Each cosmological model contains two Type IV singularities which are chosen to occur one at the end of the inflationary era and one at the end of the matter domination era. The cosmological models at early times are approximately identical to the R 2 inflation model, so these describe a slow-roll inflationary era which ends when the slow-roll parameters become of order one. The inflationary era is followed by the radiation era and after that the matter domination era follows, which lasts until the second Type IV singularity, and then the late-time acceleration era follows. The models have two appealing features: firstly they produce a nearly scale invariant power spectrum of primordial curvature perturbations and a scalar-to-tensor ratio which are compatible with the most recent observational data and secondly, it seems that the deceleration-acceleration transition is crucially affected by the presence of the second Type IV singularity which occurs at the end of the matter domination era. As we demonstrate, the Hubble horizon at early times shrinks, as expected for an initially accelerating Universe, then during the matter domination era, it expands and finally after the Type IV singularity, the Hubble horizon starts to shrink again, during the late-time acceleration era. Intriguingly enough, the deceleration-acceleration transition, occurs after the second Type IV singularity. In addition, we investigate which F(R) gravity

  12. NASA Earth Day 2014

    NASA Image and Video Library

    2014-04-22

    NASA's Administrator, Charles Bolden, conducts an experiment using circuits at NASA's Earth Day event. The event took place at Union Station in Washington, DC on April 22, 2014. Photo Credit: (NASA/Aubrey Gemignani)

  13. NASA Columbus Future Forum

    NASA Image and Video Library

    2012-02-20

    The Ohio State University Vice President for Research Dr. Caroline Whitacre, standing right, moderates the first panel discussion during NASA's Future Forum with NASA Associate Administrator for Science Mission Directorate John Grunsfeld, left, Ohio State University Graduate Research Associate Vijay Gadepally, Sen. John Glenn, NASA Administrator Charles Bolden, and NASA 2009 Astronaut Candidate and Flight Surgeon Serena Auñón, seated right, at The Ohio State University on Monday, Feb. 20, 2012, in Columbus, Ohio. Monday marked the 50th anniversary of Glenn's historic flight as the first American to orbit Earth. Photo Credit: (NASA/Bill Ingalls)

  14. NASA Education Stakeholder's Summit

    NASA Image and Video Library

    2010-09-12

    NASA Administrator Charles Bolden, far right, gives keynote remarks at the NASA Education Stakeholders’ Summit One Stop Shopping Initiative (OSSI), Monday, Sep. 13, 2010, at the Westfields Marriott Conference Center in Chantilly, VA. Administrator Bolden is joined on the panel from left to right by Leland Melvin, Education Design Team Co-Chair and NASA Astronaut; William Kelly, Manager, Public Affairs, American Society for Engineering Education; Michael Lach, Special Assistant for STEM Education, U.S. Department of Education; Cora Marrett, Acting Director, National Science Foundation; and James Stofan, NASA Acting Associate Administrator for Education. (Photo Credit: NASA/Carla Cioffi)

  15. NASA Thesaurus Data File

    NASA Technical Reports Server (NTRS)

    2012-01-01

    The NASA Thesaurus contains the authorized NASA subject terms used to index and retrieve materials in the NASA Aeronautics and Space Database (NA&SD) and NASA Technical Reports Server (NTRS). The scope of this controlled vocabulary includes not only aerospace engineering, but all supporting areas of engineering and physics, the natural space sciences (astronomy, astrophysics, planetary science), Earth sciences, and the biological sciences. The NASA Thesaurus Data File contains all valid terms and hierarchical relationships, USE references, and related terms in machine-readable form. The Data File is available in the following formats: RDF/SKOS, RDF/OWL, ZThes-1.0, and CSV/TXT.

  16. The third era of human rights: global accountability.

    PubMed

    Suter, Keith

    2007-01-01

    This article argues that the trend in the current protection of human rights may be seen as a revival of an old idea: governments are accountable for their actions. The protection of human rights has gone through three eras. In the first era, the Catholic Church in the Middle Ages claimed to rule from a divine mandate. This principle of natural law was a unifying factor in western Europe because it created a standard system of morality. The second era, beginning in the seventeenth century with the doctrine of state sovereignty, rejected that natural law. Rulers wanted to run their own territories and not be subject to foreign influence. Laws were created by the 'national sovereign' (king, queen, president, parliament, congress and so on). This legal doctrine survived for about three centuries, but the excesses of leaders such as Hitler in the middle of last century forced a re-think. Although the term 'natural law' is not used, there has been a revival of its essential meaning: that governments have to be answerable to a higher authority for their behaviour.

  17. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1996-01-01

    Close-up view of the interior of a NASA Bioreactor shows the plastic plumbing and valves (cylinders at center) to control fluid flow. A fresh nutrient bag is installed at top; a flattened waste bag behind it will fill as the nutrients are consumed during the course of operation. The drive chain and gears for the rotating wall vessel are visible at bottom center center. The NASA Bioreactor provides a low turbulence culture environment which promotes the formation of large, three-dimensional cell clusters. The Bioreactor is rotated to provide gentle mixing of fresh and spent nutrient without inducing shear forces that would damage the cells. Due to their high level of cellular organization and specialization, samples constructed in the bioreactor more closely resemble the original tumor or tissue found in the body. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.

  18. Examining spatial variability in relative sea-level in the New York City/New Jersey region during the Common Era

    NASA Astrophysics Data System (ADS)

    Walker, Jennifer; Clear, Jennifer; Garcia-Artola, Ane; Khan, Nicole; Shaw, Timothy; Corbett, Reide; Kemp, Andrew; Kopp, Robert; Horton, Benjamin

    2017-04-01

    Relative sea-level (RSL) reconstructions extend the 20th century instrumental record (tide gauge and satellite measurements) of spatial and temporal sea-level variability to provide a much longer context for recent trends and projected RSL rise. Common Era (last 2000 years) RSL reconstructions illustrate patterns of natural variability and include natural phases of climate and sea-level which will improve our knowledge basis for sea-level responses to climate changes. The northeast U.S. has exhibited varying rates in relative sea-level rise through the Common Era, primarily due to glacial isostatic adjustment. However, other factors such as ocean/atmosphere dynamics, sediment compaction, and the static equilibrium response to land ice changes, further influence the evolution of relative sea-level. The spatial variability is manifest in the tide gauge records. The tide gauge at the Battery, New York City (1856 to 2015) records a relative sea-level rise of 2.8 mm/yr whereas the tide gauge at Sandy Hook, New Jersey (1932 to 2015), 25 km southeast, records 4.1 mm/yr. Here we present a new reconstruction of RSL in northern New Jersey using geological and tide gauge data. A Common Era sea-level record from northern New Jersey fills in the spatial gap between records completed in southern New Jersey, New York City, and Connecticut. Our field study site is in Cheesequake State Park, where we observed sedimentary sequences dating back 2000 cal. yrs. BP. We use microfossil indicators preserved in salt-marsh sediments as a proxy to reconstruct RSL with decimeter precision. Salt-marsh foraminifera act as reliable RSL indicators because their modern distribution is strongly linked to tidal elevation. The recent application of microfossil-based transfer functions has enabled continuous records of RSL, extending centuries before the modern instrumental period, to be produced with a full consideration of uncertainty. We use a composite chronology of AMS 14C, pollen chrono

  19. NASA's Space Launch System: Development and Progress

    NASA Technical Reports Server (NTRS)

    Honeycutt, John; Lyles, Garry

    2016-01-01

    NASA is embarked on a new era of space exploration that will lead to new capabilities, new destinations, and new discoveries by both human and robotic explorers. Today, the International Space Station (ISS), supported by NASA's commercial partners, and robotic probes, are yielding knowledge that will help make this exploration possible. NASA is developing both the Orion crew vehicle and the Space Launch System (SLS) that will carry out a series of increasingly challenging missions that will eventually lead to human exploration of Mars. This paper will discuss the development and progress on the SLS. The SLS architecture was designed to be safe, affordable, and sustainable. The current configuration is the result of literally thousands of trade studies involving cost, performance, mission requirements, and other metrics. The initial configuration of SLS, designated Block 1, will launch a minimum of 70 metric tons (t) into low Earth orbit - significantly greater capability than any current launch vehicle. It is designed to evolve to a capability of 130 t through the use of upgraded main engines, advanced boosters, and a new upper stage. With more payload mass and volume capability than any rocket in history, SLS offers mission planners larger payloads, faster trip times, simpler design, shorter design cycles, and greater opportunity for mission success. Since the program was officially created in fall 2011, it has made significant progress toward first launch readiness of the Block 1 vehicle in 2018. Every major element of SLS continued to make significant progress in 2015. The Boosters element fired Qualification Motor 1 (QM-1) in March 2015, to test the 5-segment motor, including new insulation, joint, and propellant grain designs. The Stages element marked the completion of more than 70 major components of test article and flight core stage tanks. The Liquid Engines element conducted seven test firings of an RS-25 engine under SLS conditions. The Spacecraft

  20. NASA-STD-4005 and NASA-HDBK-4006, LEO Spacecraft Solar Array Charging Design Standard

    NASA Technical Reports Server (NTRS)

    Ferguson, Dale C.

    2007-01-01

    Two new NASA Standards are now official. They are the NASA LEO Spacecraft Charging Design Standard (NASA-STD-4005) and the NASA LEO Spacecraft Charging Design Handbook (NASA-HDBK-4006). They give the background and techniques for controlling solar array-induced charging and arcing in LEO. In this paper, a brief overview of the new standards is given, along with where they can be obtained and who should be using them.

  1. Warmest Global Temperature on Record on This Week @NASA – January 20, 2017

    NASA Image and Video Library

    2017-01-20

    NASA and the National Oceanic and Atmospheric Administration (NOAA) announced on Jan. 18, that global surface temperatures in 2016 were the warmest since modern record keeping began in 1880. The finding was based on results of independent analyses by both agencies. According to analysis by scientists at NASA’s Goddard Institute for Space Studies (GISS) in New York, 2016 is the third year in a row to set a new record for global average surface temperatures, further demonstrating a long-term warming trend. Also, Cygnus Cargo Module Arrives at KSC, Up in 30 Seconds, and Remembering Gene Cernan.

  2. NASA@Work

    NASA Technical Reports Server (NTRS)

    Davis, Jeffrey R.

    2014-01-01

    NASA@work is an agency-wide website designed to increase innovation and access to ideas and knowledge from within the NASA community. Individuals (challenge owners) post their specific problem or "challenge." Anyone in the community (solvers) can contribute to the interactive discussions and submit proposed solutions with the opportunity to win an award.

  3. Using NASA Space Imaging Technology to Teach Earth and Sun Topics

    NASA Astrophysics Data System (ADS)

    Verner, E.; Bruhweiler, F. C.; Long, T.

    2011-12-01

    We teach an experimental college-level course, directed toward elementary education majors, emphasizing "hands-on" activities that can be easily applied to the elementary classroom. This course, Physics 240: "The Sun-Earth Connection" includes various ways to study selected topics in physics, earth science, and basic astronomy. Our lesson plans and EPO materials make extensive use of NASA imagery and cover topics about magnetism, the solar photospheric, chromospheric, coronal spectra, as well as earth science and climate. In addition we are developing and will cover topics on ecosystem structure, biomass and water on Earth. We strive to free the non-science undergraduate from the "fear of science" and replace it with the excitement of science such that these future teachers will carry this excitement to their future students. Hands-on experiments, computer simulations, analysis of real NASA data, and vigorous seminar discussions are blended in an inquiry-driven curriculum to instill confident understanding of basic physical science and modern, effective methods for teaching it. The course also demonstrates ways how scientific thinking and hands-on activities could be implemented in the classroom. We have designed this course to provide the non-science student a confident basic understanding of physical science and modern, effective methods for teaching it. Most of topics were selected using National Science Standards and National Mathematics Standards that are addressed in grades K-8. The course focuses on helping education majors: 1) Build knowledge of scientific concepts and processes; 2) Understand the measurable attributes of objects and the units and methods of measurements; 3) Conduct data analysis (collecting, organizing, presenting scientific data, and to predict the result); 4) Use hands-on approaches to teach science; 5) Be familiar with Internet science teaching resources. Here we share our experiences and challenges we face while teaching this course.

  4. NASA Education Stakeholder's Summit

    NASA Image and Video Library

    2010-09-12

    NASA Administrator Charles Bolden gives keynote remarks at the NASA Education Stakeholders’ Summit One Stop Shopping Initiative (OSSI), Monday, Sep. 13, 2010, at the Westfields Marriott Conference Center in Chantilly, VA. (Photo Credit: NASA/Carla Cioffi)

  5. NASA Earth Day 2014

    NASA Image and Video Library

    2014-04-22

    Students listen intently while NASA's Director, Earth Science Division, Mike Freilich, speaks at NASA's Earth Day event. The event took place at Union Station in Washington, DC on April 22, 2014. Photo Credit: (NASA/Aubrey Gemignani)

  6. Women's History Month at NASA

    NASA Image and Video Library

    2011-03-14

    NASA Deputy Administrator Lori Garver, far left at table, answers a students question at a Women's History Month event at NASA Headquarters, Wednesday, March 16, 2011 in Washington. Garver is joined on the panel by NASA astronaut Tracy Caldwell Dyson, center, and NASA Aerospace Engineer Sabrina Thompson. The event entitled Women Inspiring the Next Generation to Reveal the Unknown is a joint venture with NASA and the White House Council on Women and Girls. Photo Credit: (NASA/Carla Cioffi)

  7. Nuclear weapons modernizations

    NASA Astrophysics Data System (ADS)

    Kristensen, Hans M.

    2014-05-01

    This article reviews the nuclear weapons modernization programs underway in the world's nine nuclear weapons states. It concludes that despite significant reductions in overall weapons inventories since the end of the Cold War, the pace of reductions is slowing - four of the nuclear weapons states are even increasing their arsenals, and all the nuclear weapons states are busy modernizing their remaining arsenals in what appears to be a dynamic and counterproductive nuclear competition. The author questions whether perpetual modernization combined with no specific plan for the elimination of nuclear weapons is consistent with the nuclear Non-Proliferation Treaty and concludes that new limits on nuclear modernizations are needed.

  8. NASA Education Stakeholder's Summit

    NASA Image and Video Library

    2010-09-12

    Special Assitant for STEM Education, U. S. Department of Education, Michael Lach, far right, addresses guests at the NASA Education Stakeholders’ Summit One Stop Shopping Initiative (OSSI), Monday, Sep. 13, 2010, at the Westfields Marriott Conference Center in Chantilly, VA. Seated from right are James Stofan, NASA Acting Associate Administrator for Education; Charles Bolden, NASA Administrator; and Cora B. Marrett, Acting Director, National Science Foundation. (Photo Credit: NASA/Carla Cioffi)

  9. Modified enhanced recovery after surgery (ERAS) protocols for patients with obstructive colorectal cancer.

    PubMed

    Shida, Dai; Tagawa, Kyoko; Inada, Kentaro; Nasu, Keiichi; Seyama, Yasuji; Maeshiro, Tsuyoshi; Miyamoto, Sachio; Inoue, Satoru; Umekita, Nobutaka

    2017-02-16

    Enhanced recovery after surgery (ERAS) protocols are now well-known to be useful for elective colorectal surgery, as they result in shorter hospital stays without adversely affecting morbidity. However, the efficacy and safety of ERAS protocols for patients with obstructive colorectal cancer have yet to be clarified. We evaluated 122 consecutive resections for obstructive colorectal cancer performed between July 2008 and November 2012 at Tokyo Metropolitan Bokutoh Hospital. Patients with rupture or impending rupture and those who received simple colostomy were excluded. The first set of 42 patients was treated based on traditional protocols, and the latter 80 according to modified ERAS protocols. The main endpoints were length of postoperative hospital stay, postoperative short-term morbidity, rate of readmission within 30 days, and mortality. Differences in modified ERAS protocols relative to traditional care include intensive preoperative counseling (by both surgeons and anesthesiologists), perioperative fluid management (avoidance of sodium/fluid overload), shortening of postoperative fasting period and early provision of oral nutrition, intraoperative warm air body heating, enforced postoperative mobilization, stimulation of gut motility, early removal of urinary catheter, and a multidisciplinary team approach to care. Median (interquartile range) postoperative hospital stay was 10 (10-14.25) days in the traditional group, and seven (7-8.75) days in the ERAS group, showing a 3-day reduction in hospital stay (p < 0.01). According to the Clavien-Dindo classification, overall incidences of grade 2 or higher postoperative complications for the traditional and ERAS groups were 15 and 10% (p = 0.48), and 30-day readmission rates were 0 and 1.3% (p = 1.00), respectively. As for mortality, one patient in the traditional group died and none in the ERAS group (p = 0.34). Modified ERAS protocols for obstructive colorectal cancer reduced hospital stay

  10. Comparison of NASTRAN analysis with ground vibration results of UH-60A NASA/AEFA test configuration

    NASA Technical Reports Server (NTRS)

    Idosor, Florentino; Seible, Frieder

    1990-01-01

    Preceding program flight tests, a ground vibration test and modal test analysis of a UH-60A Black Hawk helicopter was conducted by Sikorsky Aircraft to complement the UH-60A test plan and NASA/ARMY Modern Technology Rotor Airloads Program. The 'NASA/AEFA' shake test configuration was tested for modal frequencies and shapes and compared with its NASTRAN finite element model counterpart to give correlative results. Based upon previous findings, significant differences in modal data existed and were attributed to assumptions regarding the influence of secondary structure contributions in the preliminary NASTRAN modeling. An analysis of an updated finite element model including several secondary structural additions has confirmed that the inclusion of specific secondary components produces a significant effect on modal frequency and free-response shapes and improves correlations at lower frequencies with shake test data.

  11. Scaled Composites' Proteus aircraft and an F/A-18 Hornet from NASA's Dryden Flight Research Center d

    NASA Technical Reports Server (NTRS)

    2002-01-01

    Scaled Composites' Proteus aircraft and an F/A-18 Hornet from NASA's Dryden Flight Research Center during a low-level flyby at Las Cruces Airport in New Mexico. The unique Proteus aircraft served as a test bed for NASA-sponsored flight tests designed to validate collision-avoidance technologies proposed for uninhabited aircraft. The tests, flown over southern New Mexico in March, 2002, used the Proteus as a surrogate uninhabited aerial vehicle (UAV) while three other aircraft flew toward the Proteus from various angles on simulated collision courses. Radio-based 'detect, see and avoid' equipment on the Proteus successfully detected the other aircraft and relayed that information to a remote pilot on the ground at Las Cruces Airport. The pilot then transmitted commands to the Proteus to maneuver it away from the potential collisions. The flight demonstration, sponsored by NASA Dryden Flight Research Center, New Mexico State University, Scaled Composites, the U.S. Navy and Modern Technology Solutions, Inc., were intended to demonstrate that UAVs can be flown safely and compatibly in the same skies as piloted aircraft.

  12. NASA Earth Day 2014

    NASA Image and Video Library

    2014-04-22

    NASA's Administrator, Charles Bolden watches as some students conduct an experiment with a balloon at NASA's Earth Day event. The event took place at Union Station in Washington, DC on April 22, 2014. Photo Credit: (NASA/Aubrey Gemignani)

  13. NASA's Software Safety Standard

    NASA Technical Reports Server (NTRS)

    Ramsay, Christopher M.

    2005-01-01

    NASA (National Aeronautics and Space Administration) relies more and more on software to control, monitor, and verify its safety critical systems, facilities and operations. Since the 1960's there has hardly been a spacecraft (manned or unmanned) launched that did not have a computer on board that provided vital command and control services. Despite this growing dependence on software control and monitoring, there has been no consistent application of software safety practices and methodology to NASA's projects with safety critical software. Led by the NASA Headquarters Office of Safety and Mission Assurance, the NASA Software Safety Standard (STD-18l9.13B) has recently undergone a significant update in an attempt to provide that consistency. This paper will discuss the key features of the new NASA Software Safety Standard. It will start with a brief history of the use and development of software in safety critical applications at NASA. It will then give a brief overview of the NASA Software Working Group and the approach it took to revise the software engineering process across the Agency.

  14. NASA metrication activities

    NASA Technical Reports Server (NTRS)

    Vlannes, P. N.

    1978-01-01

    NASA's organization and policy for metrification, history from 1964, NASA participation in Federal agency activities, interaction with nongovernmental metrication organizations, and the proposed metrication assessment study are reviewed.

  15. Curation of Microscopic Astromaterials by NASA: "Gathering Dust Since 1981"

    NASA Technical Reports Server (NTRS)

    Frank, D. R.; Bastien, R. K.; Rodriguez, M.; Gonzalez, C.; Zolensky, M. E.

    2013-01-01

    Employing the philosophy that "Small is Beautiful", NASA has been collecting and curating microscopic astromaterials since 1981. These active collections now include interplanetary dust collected in Earth's stratosphere by U-2, ER-2 and WB-57F aircraft (the Cosmic Dust Program - our motto is "Gathering dust since 1981"), comet Wild-2 coma dust (the Stardust Mission), modern interstellar dust (also the Stardust Mission), asteroid Itokawa regolith dust (the Hayabusa Mission - joint curation with JAXA-ISAS), and interplanetary dust impact features on recovered portions of the following spacecraft: Skylab, the Solar Maximum Satellite, the Palapa Satellite, the Long Duration Exposure Facility (LDEF), the MIR Space Station, the International Space Station, and the Hubble Space Telescope (all in the Space Exposed Hardware Laboratory).

  16. Classroom Activities for the Progressive Era and the World War I Draft.

    ERIC Educational Resources Information Center

    Mills, Randy

    1986-01-01

    Provides discussion questions, activities, and projects to be used with EJ515083, "The Progressive Era and the World War I Draft." Includes three political cartoons and two World War I-era songs of opposing viewpoints. (JDH)

  17. NASA Future Forum

    NASA Image and Video Library

    2012-02-21

    Sen. John Glenn delivers the closing remarks for NASA's Future Forum at The Ohio State University on Tuesday, Feb. 21, 2012 in Columbus, Ohio. The NASA Future Forum features panel discussions on the importance of education to our nation's future in space, the benefit of commercialized space technology to our economy and lives here on Earth, and the shifting roles for the public, commercial and international communities in space. Photo Credit: (NASA/Bill Ingalls)

  18. NASA commercial programs

    NASA Technical Reports Server (NTRS)

    1988-01-01

    An expanded role for the U.S. private sector in America's space future has emerged as a key national objective, and NASA's Office of Commercial Programs is providing a focus for action. The Office supports new high technology commercial space ventures, the commercial application of existing aeronautics and space technology, and expanded commercial access to available NASA capabilities and services. The progress NASA has made in carrying out its new assignment is highlighted.

  19. Modern Day Re-analysis of Pinatubo SO2 Injection, Cloud dispersion and Stratospheric Aerosols

    NASA Astrophysics Data System (ADS)

    Bhartia, P. K.; Krotkov, N. A.; Aquila, V.; Hughes, E. J.; Li, C.; Fisher, B. L.

    2016-12-01

    Cataclysmic June 15 1991 eruption of Mt. Pinatubo injected largest amount of SO2 in the lower stratosphere during the satellite era. The resulting volcanic clouds were tracked by the NASA's Nimbus 7 TOMS sensor that provided first estimates of total emissions of SO2 gas ( 15+/-3 Mt). Over time SO2 converted to long-lasting sulfate aerosols affecting radiation balance and composition of the stratosphere. Large numbers of articles and papers published in the past 25 years make this the most well-studied volcanic eruption. Still, several unresolved scientific issues remain: SO2 injection height, subsequent lofting of SO2 and aerosols in the stratosphere, how much sulfate aerosols were produced in the eruption (i.e., initial sulfate to SO2 ratio), and impact on stratospheric ozone. To answer these questions we have re-analyzed past satellite measurements using modern day tools, such as re-analyzed wind data from Goddard Modeling and Assimilation Office (GMAO), improved trajectory analysis tools, better radiative transfer model to process backscatter UV data from N7/TOMS and two NOAA SBUV/2s sensors, which provided measurements at shorter UV wavelengths that are sensitive to aerosols and SO2 in the mid stratosphere ( 25 km). We have also re-analyzed aerosol data from SAGE, AVHRR, and several instruments on the UARS satellite. These data provide strong support for recent assessment by modelers that the bulk of SO2 mass injected by the volcano was well below the 25 km altitude, contrary to earlier estimates. We also find convincing evidence that there was significant amount of sulfate aerosols embedded even in the day-old SO2 cloud. These results strongly support the hypothesis that SO2 gas self-lofted to 25 km as seeen by UARS MLS several weeks after the eruption and aerosols to 35 km, as seen by the SAGE sensor several months later.

  20. NASA Bioreactor

    NASA Technical Reports Server (NTRS)

    1998-01-01

    The heart of the bioreactor is the rotating wall vessel, shown without its support equipment. Volume is about 125 mL. The work is sponsored by NASA's Office of Biological and Physical Research. The bioreactor is managed by the Biotechnology Cell Science Program at NASA's Johnson Space Center (JSC). NASA-sponsored bioreactor research has been instrumental in helping scientists to better understand normal and cancerous tissue development. In cooperation with the medical community, the bioreactor design is being used to prepare better models of human colon, prostate, breast and ovarian tumors. Cartilage, bone marrow, heart muscle, skeletal muscle, pancreatic islet cells, liver and kidney are just a few of the normal tissues being cultured in rotating bioreactors by investigators.