Comparative study of optical and scintillation properties of Tm3+:YAG, and Tm3+:LuAG single crystals

NASA Astrophysics Data System (ADS)

Fujimoto, Yutaka; Sugiyama, Makoto; Yanagida, Takayuki; Wakahara, Shingo; Suzuki, Shotaro; Kurosawa, Shunsuke; Chani, Valery; Yoshikawa, Akira

2013-09-01

The optical and scintillation properties of Tm3+-doped yttrium aluminum garnet Y3Al5O12 (YAG) and Tm3+-doped lutetium aluminum garnet Lu3Al5O12 (LuAG) are compared. The Tm3+-doped single crystals were grown by the micro-pulling down (μ-PD) technique. Both crystals demonstrated some emission peaks originated from 4f-4f forbidden transition of Tm3+ under 241Am alpha-ray excitation. The scintillation decay time of Tm3+-doped YAG was similar to that of LuAG. When irradiated by the gamma-rays from a 137Cs source, the relative scintillation light yields of Tm:YAG was 90% greater than that of Tm:LuAG.

Measurement of the 169Tm(n,3n) 167Tm cross section and the associated branching ratios in the decay of 167Tm [Measurement of the 169Tm(n,3n) 167Tm cross section and the branching ratios in the decay of 167Tm

DOE PAGES

Champine, B.; Gooden, M. E.; Krishichayan, .; ...

2016-01-14

The cross section for the 169Tm(n,3n) 167Tm reaction was measured from 17 to 22 MeV using quasimonoenergetic neutrons produced by the 2H(d,n) 3He reaction. This energy range was studied to resolve the discrepancy between previous (n,3n) cross-section measurements. In addition, the absolute γ-ray branching ratios following the electron-capture decay of 167Tm were measured. Furthermore, these results provide more reliable nuclear data for an important diagnostic that is used at the National Ignition Facility to estimate the yield of reaction-in-flight neutrons produced via the inertial-confinement-fusion plasma in deuterium-tritium capsules.

Development of flashlamp-pumped Q-switched Ho:Tm:Cr:YAG lasers for mid-infrared LIDAR application

NASA Technical Reports Server (NTRS)

Choi, Young S.; Kim, Kyong H.; Whitney, Donald A.; Hess, Robert V.; Barnes, Norman P.; Bair, Clayton H.; Brockman, Philip

1989-01-01

A flashlamp-pumped 2.1 micron Ho:Tm:Cr:YAG laser was studied for both normal mode and Q-switched operations under a wide variety of experimental conditions in order to optimize performance. Laser output energy, slope efficiency, threshold and pulselength were determined as a function of operating temperature, output mirror reflectivity, input electrical energy and Q-switch opening time. The measured normal-mode laser thresholds of a Ho(3+) (0.45 atomic percent):Tm(3+) (2.5 atomic percent):Cr(3+) (0.8 atomic percent):YAG crystal ranged form 26 to 50 J between 120 and 200 K with slope efficiencies up to 0.36 percent with a 60 percent reflective output mirror. Under Q-switched operation the slope efficiency was 90 percent of the normal-mode result. Development of solid state lasers with Ho(3+), Tm(3+) and/or Er(3+) doped crystals has been pursued by NASA for eye-dafe mid-infrared LIDAR (light detection and ranging) application. As a part of the project, the authors have been working on evaluating Ho(3+):Tm(3+):Cr(3+):YAG crystals for normal-mode and Q-switched 2.1 micron laser operations in order to determine an optimum Tm(3+) concentration under flashlamp pumping conditions. Lasing properties of the Ho(3+) in the mid-infrared region have been studied by many research groups since the early 1960's. However, the technology of those lasers is still premature for lidar application. In order to overcome the inefficiency related to narrow absorption bands of the Ho(3+), Tm(3+) and Er(3+), the erbium has been replaced by chromium. The improvement in flashlamp-pumped Ho(3+) laser efficiency has been demonstrated recently by several research groups by utilizing the broad absorption spectrum of Cr(3+) which covers the flashlamp's emission spectrum. Efficient energy transfer to the Tm(3+) and then the Ho(3+) occurs subsequently. It is known that high Tm(3+) concentration and low Ho(3+) concentration are preferred to achieve a quantum efficiency approaching two and to avoid

Absolute calibration accuracy of L4 TM and L5 TM sensor image pairs

USGS Publications Warehouse

Chander, G.; Micijevic, E.

2006-01-01

The Landsat suite of satellites has collected the longest continuous archive of multispectral data of any land-observing space program. From the Landsat program's inception in 1972 to the present, the Earth science user community has benefited from a historical record of remotely sensed data. However, little attention has been paid to ensuring that the data are calibrated and comparable from mission to mission, Launched in 1982 and 1984 respectively, the Landsat 4 (L4) and Landsat 5 (L5) Thematic Mappers (TM) are the backbone of an extensive archive of moderate resolution Earth imagery. To evaluate the "current" absolute accuracy of these two sensors, image pairs from the L5 TM and L4 TM sensors were compared. The approach involves comparing image statistics derived from large common areas observed eight days apart by the two sensors. The average percent differences in reflectance estimates obtained from the L4 TM agree with those from the L5 TM to within 15 percent. Additional work to characterize the absolute differences between the two sensors over the entire mission is in progress.

Reliability and Validity of the Zephyr[TM] BioHarness[TM] to Measure Respiratory Responses to Exercise

ERIC Educational Resources Information Center

Hailstone, Jono; Kilding, Andrew E.

2011-01-01

The Zephyr[TM] BioHarness[TM] (Zephyr Technology, Auckland, New Zealand) is a wireless physiological monitoring system that has the ability to measure respiratory rate unobtrusively. However, the ability of the BioHarness[TM] to accurately and reproducibly determine respiratory rate across a range of intensities is currently unknown. The aim of…

NASA-UVA Light Aerospace Alloy and Structures Technology Program (LA2ST)

NASA Technical Reports Server (NTRS)

Gangloff, Richard P.; Scully, John R.; Stoner, Glenn E.; Thornton, Earl A.; Wawner, Franklin E., Jr.; Wert, John A.

1993-01-01

The NASA-UVA Light Aerospace Alloy and Structures Technology (LA2ST) Program continues a high level of activity. Progress achieved between 1 Jan. and 30 Jun. 1993 is reported. The objective of the LA2ST Program is to conduct interdisciplinary graduate student research on the performance of next generation, light weight aerospace alloys, composites, and thermal gradient structures in collaboration with NASA-Langley researchers. The following projects are addressed: environmental fatigue of Al-Li-Cu alloys; mechanisms of localized corrosion and environmental fracture in Al-Cu-Li-Mg-Ag alloy X2095 and compositional variations; the effect of zinc additions on the precipitation and stress corrosion cracking behavior of alloy 8090; hydrogen interactions with Al-Li-Cu alloy 2090 and model alloys; metastable pitting of aluminum alloys; cryogenic fracture toughness of Al-Cu-Li + In alloys; the fracture toughness of Weldalite (TM); elevated temperature cracking of advanced I/M aluminum alloys; response of Ti-1100/SCS-6 composites to thermal exposure; superplastic forming of Weldalite (TM); research to incorporate environmental effects into fracture mechanics fatigue life prediction codes such as NASA FLAGRO; and thermoviscoplastic behavior.

20 years of Tm:Ho:YLF and LuLF Laser Development for Global Winds Measurements

NASA Technical Reports Server (NTRS)

Singh, Upendra N.; Walsh, Brian M.; Yu, Jirong; Petros, Mulugeta; Kavaya, Michael J.; Barnes, Norman P.

2014-01-01

NASA Langley Research Center has a long history of developing 2 micron lasers. From fundamental spectroscopy research, theoretical prediction of new materials, laser demonstration and engineering of lidar systems, it has been a very successful program spanning around two decades. This article covers the program development from the early research to the present instrumentation. A brief historical perspective of Tm:Ho work by early researchers is also given.

Modified LaRC(TM)-IA Polyimides

NASA Technical Reports Server (NTRS)

St. Clair, Terry L.; Chang, Alice C.; Hou, Tan H.; Working, Dennis C.

1994-01-01

Modified versions of thermoplastic polyimide LaRC(TM)-IA incorporate various amounts of additional, rigid moieties into backbones of LaRC(TM)-IA molecules. Modified versions more resistant to solvents and exhibit higher glass-transition temperatures, yet retain melt-flow processability of unmodified LaRC(TM)-IA.

Phonon anomalies in intermediate valent TmXSe and TmSe1 - yTey

NASA Astrophysics Data System (ADS)

Boppart, H.; Treindl, A.; Wachter, P.

1981-03-01

In TmxSe and TmSe1-yTey the degree of valence mixing can be adjusted between nearly 3+ for Tm0.87Se and 2.55+ for TmSe0.7Te0.3. The measurement of sound velocities vL, vTl and vT2 and the evaluation of the Raman effect for various compositions permit the derivation of LA [111] phonon dispersion at critical points in the Brillouin zone. vL decreases with increasing valence mixing. Near the middle of the zone the LA branch gets a dip for intermediate valent compositions, resulting in a characteristic peak in the Ramn spectrum at about 60 cm-1. The elastic constant c12 has been found negative for Tm0.99Se, also at 4.2 K. For uniaxial pressures c12 exhibits strong nonlinearities and even changes sign with pressure in an intermediate valent composition. The optical phonon frequencies, LO (L) also soften proportional with the degree of valence mixing.

Actively mode-locked Tm-Ho:LiYF4 and Tm-Ho:BaY2F8 lasers

NASA Astrophysics Data System (ADS)

Gatti, D.; Galzerano, G.; Toncelli, A.; Tonelli, M.; Laporta, P.

2007-01-01

We report on the generation of mode-locking pulse trains with high average output powers from diode-pumped Tm-Ho:LiYF4 and Tm-Ho:BaY2F8 lasers emitting at around 2 μm. The highest output power of 365 mW was obtained with the Tm-Ho:YLF4 laser, whereas the shortest pulse duration of 120 ps and the widest tunability range of 59 nm was achieved with the Tm-Ho:BaY2F8 laser.

Blue upconversion with excitation into Tm ions at 780 nm in Yb- and Tm-codoped fluoride crystals

NASA Astrophysics Data System (ADS)

Zhang, X. X.; Hong, P.; Bass, M.; Chai, B. H. T.

1995-04-01

Strong blue emissions have been observed in fluoride crystals, such as LiYF4, BaY2F8, and KYF4, codoped with Tm3+ and Yb3+ when excited into the Tm3+ 3F4 state at ~780 nm. Energy transfer from Tm3+ to Yb3+ ions followed by the transfer from Yb3+ to Tm3+ was demonstrated to be responsible for the upconversion process. A pumping scheme is proposed based on this upconversion mechanism for blue-laser applications using these materials.

High Efficiency End-Pumped Ho:Tm:YLF Disk Amplifier

NASA Technical Reports Server (NTRS)

Yu, Jirong; Singh, Upendra N.; Petros, Mulugeta; Axenson, Theresa J.; Barnes, Norman P.

1999-01-01

Space based coherent lidar for global wind measurement requires an all solid state laser system with high energy, high efficiency and narrow linewidth that operates in the eye safe region. A Q-switched, diode pumped Ho:Tm:YLF 2 micrometer laser with output energy of as much as 125 mJ at 6 Hz with an optical-to-optical efficiency of 3% has been reported. Single frequency operation of the laser was achieved by injection seeding. The design of this laser is being incorporated into NASA's SPARCLE (SPAce Readiness Coherent Lidar Experiment) wind lidar mission. Laser output energy ranging from 500 mJ to 2 J is required for an operational space coherent lidar. We previously developed a high energy Ho:Tm:YLF master oscillator and side pumped power amplifier system and demonstrated a 600-mJ single frequency pulse at a repetition rate of 10 Hz. Although the output energy is high, the optical-to-optical efficiency is only about 2%. Designing a high energy, highly efficient, conductively cooled 2-micrometer laser remains a challenge. In this paper, the preliminary result of an end-pumped amplifier that has a potential to provide a factor 3 of improvement in the system efficiency is reported.

TM triple-mode microwave filter

NASA Astrophysics Data System (ADS)

Lai, S.-L.; Lin, W.-G.

1990-12-01

A novel realization of triple-mode six-pole microwave filters that use only TM modes is presented. The application involves TM triple degeneracies in cylindrical cavities using triple-mode elliptic function filter synthesis. Experimental results are reported.

Bibliography of NASA published reports on general aviation, 1975 to 1981

NASA Technical Reports Server (NTRS)

1981-01-01

This bibliography lists 478 documents which relate to all heavier-than-air fixed wing aircraft exclusive of military types and those used for commercial air transport. An exception is the inclusion of commuter transport aircraft types within the general aviation category. NASA publications included in this bibliography are: conference publications (CP), reference publications (RP), technical memorandums (TM, TMX), technical notes (TN), technical papers (TP), and contractor reports (CR). In addition, papers and articles on NASA general aviation programs published by technical societies (AIAA, SAE, etc.) are included, as well as those listed in NASA's Scientific and Technical Aerospace Reports (STAR) Journal. Author and subject indexes are also provided to facilitate use of the bibliography.

NASA Glenn Steady-State Heat Pipe Code GLENHP: Compilation for 64- and 32-Bit Windows Platforms

NASA Technical Reports Server (NTRS)

Tower, Leonard K.; Geng, Steven M.

2016-01-01

A new version of the NASA Glenn Steady State Heat Pipe Code, designated "GLENHP," is introduced here. This represents an update to the disk operating system (DOS) version LERCHP reported in NASA/TM-2000-209807. The new code operates on 32- and 64-bit Windows-based platforms from within the 32-bit command prompt window. An additional evaporator boundary condition and other features are provided.

Temperature dependence of LRE-HRE-TM thin films

NASA Astrophysics Data System (ADS)

Li, Zuoyi; Cheng, Xiaomin; Lin, Gengqi; Li, Zhen; Huang, Zhixin; Jin, Fang; Wang, Xianran; Yang, Xiaofei

2003-04-01

Temperature dependence of the properties of RE-TM thin films is very important for MO recording. In this paper, we studied the temperature dependence of the magnetic and magneto-optical properties of the amorphous LRE-HRE-TM single layer thin films and LRE-HRE-TM/HRE-TM couple-bilayered thin films. For LRE-HRE-TM single layer thin films, the temperature dependence of the magnetization was investigated by using the mean field theory. The experimental and theoretical results matched very well. With the LRE substitution in HRE-TM thin film, the compensation temperature Tcomp decreased and the curie temperature Tc remained unchanged. Kerr rotation angle became larger and the saturation magnetization Ms at room temperature increased. For LRE-HRE-TM/HRE-TM couple-bilayered thin films, comparisons of the temperature dependences of the coercivities and Kerr rotation angles were made between isolated sublayers and couple-bilayered thin film.

Measurement of the 169Tm (n ,3 n ) 167Tm cross section and the associated branching ratios in the decay of 167Tm

NASA Astrophysics Data System (ADS)

Champine, B.; Gooden, M. E.; Krishichayan, Norman, E. B.; Scielzo, N. D.; Stoyer, M. A.; Thomas, K. J.; Tonchev, A. P.; Tornow, W.; Wang, B. S.

2016-01-01

The cross section for the 169Tm(n ,3 n ) 167Tm reaction was measured from 17 to 22 MeV using quasimonoenergetic neutrons produced by the 2H(d ,n ) 3He reaction. This energy range was studied to resolve the discrepancy between previous (n ,3 n ) cross-section measurements. In addition, the absolute γ -ray branching ratios following the electron-capture decay of 167Tm were measured. These results provide more reliable nuclear data for an important diagnostic that is used at the National Ignition Facility to estimate the yield of reaction-in-flight neutrons produced via the inertial-confinement-fusion plasma in deuterium-tritium capsules.

Cryogenic-cooled Tm:SBN tunable laser

NASA Astrophysics Data System (ADS)

Švejkar, Richard; Šulc, Jan; Němec, Michal; Jelínková, Helena; Doroshenko, Maxim E.; Papashvili, Alexander G.; Batygov, Sergei H.; Osiko, Vyacheslav V.

2017-12-01

In this work the temperature dependence of spectroscopic and laser properties of new ac- tive medium Tm:SBN (Strontium-Barium Niobate, SrxBa1-xNb2O6, x = 0.61). The tested sample of Tm:SBN (2 wt. % of Tm2O3) appropriate for generation of laser radiation at 1.88 μm had plan-parallel polished faces without anti-reflection (thickness 6.65 mm). During spectroscopy and laser experiments the Tm:SBN was at- tached to temperature-controlled copper holder and was placed in a vacuum chamber. The transmission and emission spectra of Tm:SBN and the fluorescence decay time were measured depending on temperature range 80 - 350 K. The fluorescence decay time was measured to be 3.5 ms and 2.8 ms at 80 and 350 K, respectively. Longitudinal excitation of Tm:SBN was carried out by a fibre-coupled laser diode (pulse duration 10 ms, rep- etition rate 10 Hz, pump wavelength 793 nm). The laser resonator was hemispherical, 146 mm long, with flat pumping mirror (HR @1.8 - 2.1 μm) and spherical output coupler (r = 150 mm, R = 97.5 % @1.8 - 2.1 μm). The Tm:SBN laser properties were investigated at temperature range 80 - 300 K. The highest slope efficiency with respect to absorbed pumped power was 3 % at 80 K. The maximum output peak amplitude power was 0.12 W at 80 K, i.e. 3.2 times higher than it was measured at 200 K. Tunability of laser wavelength at 80 K in the range of 1827 - 1962 nm was obtained by using SiO2 birefringent filter. At 300 K, wavelength tunability reached 1859 - 1970 nm. Thus, the new Tm:SBN crystal can be an useful laser material in the region of 2 μm.

Automated Tow Placed LaRC(TM)-PETI-5 Composites

NASA Technical Reports Server (NTRS)

Hou, T. H.; Belvin, H. L.; Johnston, N. J.

2001-01-01

LaRC(TM)-PETI-5 is a PhenylEthynyl-Terminated Imide resin developed at NASA Langley Research Center (LaRC) during the 1990s. It offers a combination of attractive composite and adhesive properties. IM7/LaRC(TM)-PETI-5 composites exhibit thermal and thermo-oxidative stability typical of polyimides, superior chemical resistance and processability, excellent mechanical properties, toughness and damage tolerance. It was selected for study in the High Speed Research program aimed at developing technologies for a future supersonic aircraft, the High Speed Civil Transport, with a projected life span of 60 000 h at a cruise speed up to Mach 2.4. Robust autoclave processing cycles for LaRC(TM)-PETI-5 composites have been thoroughly designed and demonstrated, which involved hand lay-up of solvent-ladened 'wet' prepregs. However, this type of processing is not only costly but also environmentally unfriendly. Volatile management and shrinkage could become serious problems in the fabrication of large complex airframe structural subcomponents. Robotic tow placement technology utilizing 'dry' material forms represents a new fabrication process which overcomes these deficiencies. This work evaluates and compares mechanical properties of composites fabricated by heated head automated tow placement (dry process) with those obtained by hand lay-up/autoclave fabrication (wet process). Thermal and rheological properties of the robotically as-placed uncured composites were measured. A post-cure cycle was designed due to the requirement of the PETI-5 resin for a 370 C/1 h hold to reach full cure, conditions which cannot be duplicated during heated head robotic placement. Mechanical properties such as 0 degree flexural strength and modulus, open hole tensile and compressive strength and moduli, reduced section compression dogbone compressive strength, and modified zippora-medium small (MZ-MS) tensile and compressive properties were obtained on the post-cured panels. These properties

Alertness Management In Flight Operations: A NASA Education and Training Module

NASA Technical Reports Server (NTRS)

Rosekind, Mark R.; Lebacqz, Victor J.; Gander, Philippa H.; Co, Elizabeth L.; Weldon, Keri J.; Smith, Roy M.; Miller, Donna L.; Gregory, Kevin B.; Statler, Irving C. (Technical Monitor)

1994-01-01

Since 1980, the NASA Ames Fatigue Countermeasures Program has been conducting research on sleep, circadian rhythms, and fatigue in a variety of flight operations 1. An original goal of the program was to return the scientific and operational knowledge to the aviation industry. To meet this goal, the NASA Ames Fatigue Countermeasures Program has created an Education and Training Module entitled, "Strategies for Alertness Management in Flight Operations." The Module was designed to meet three objectives: 1) explain the current state of knowledge about the physiological mechanisms underlying fatigue, 2) demonstrate how this knowledge can be applied to improve flight crew sleep, performance, and alertness, and 3) offer countermeasure recommendations. The Module is composed of two components: 1) a 60-minute live presentation provided by a knowledgeable individual and 2) a NASA/FAA Technical Memorandum (TM) that contains the presentation materials and appendices with complementary information. The TM is provided to all individuals attending the live presentation. The Module content is divided into three parts: 1) basic information on sleep, sleepiness, circadian rhythms, fatigue, and how flight operations affect these physiological factors, 2) common misconceptions about sleep, sleepiness, and fatigue, and 3) alertness management strategies. The Module is intended for pilots, management personnel, schedulers, flight attendants, and the many other individuals involved in the aviation system.

Concurrent Validity of LibQUAL+[TM] Scores: What Do LibQUAL+[TM] Scores Measure?

ERIC Educational Resources Information Center

Thompson, Bruce; Cook, Colleen; Kyrillidou, Martha

2005-01-01

The present study investigated the validity of LibQUAL+[TM] scores, and specifically how total and subscale LibQUAL+[TM] scores are associated with self-reported, library-related satisfaction and outcomes scores. Participants included 88,664 students and faculty who completed the American English (n[AE] = 69,494) or the British English (n[BE] =…

Design for reliability: NASA reliability preferred practices for design and test

NASA Technical Reports Server (NTRS)

Lalli, Vincent R.

1994-01-01

This tutorial summarizes reliability experience from both NASA and industry and reflects engineering practices that support current and future civil space programs. These practices were collected from various NASA field centers and were reviewed by a committee of senior technical representatives from the participating centers (members are listed at the end). The material for this tutorial was taken from the publication issued by the NASA Reliability and Maintainability Steering Committee (NASA Reliability Preferred Practices for Design and Test. NASA TM-4322, 1991). Reliability must be an integral part of the systems engineering process. Although both disciplines must be weighed equally with other technical and programmatic demands, the application of sound reliability principles will be the key to the effectiveness and affordability of America's space program. Our space programs have shown that reliability efforts must focus on the design characteristics that affect the frequency of failure. Herein, we emphasize that these identified design characteristics must be controlled by applying conservative engineering principles.

Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sciuto, Tracey E.; Merley, Anne; Lin, Chi-Iou

2015-09-25

Transmembrane-4 L-six family member-1 (TM4SF1) is a small plasma membrane-associated glycoprotein that is highly and selectively expressed on the plasma membranes of tumor cells, cultured endothelial cells, and, in vivo, on tumor-associated endothelium. Immunofluorescence microscopy also demonstrated TM4SF1 in cytoplasm and, tentatively, within nuclei. With monoclonal antibody 8G4, and the finer resolution afforded by immuno-nanogold transmission electron microscopy, we now demonstrate TM4SF1 in uncoated cytoplasmic vesicles, nuclear pores and nucleoplasm. Because of its prominent surface location on tumor cells and tumor-associated endothelium, TM4SF1 has potential as a dual therapeutic target using an antibody drug conjugate (ADC) approach. For ADC to bemore » successful, antibodies reacting with cell surface antigens must be internalized for delivery of associated toxins to intracellular targets. We now report that 8G4 is efficiently taken up into cultured endothelial cells by uncoated vesicles in a dynamin-dependent, clathrin-independent manner. It is then transported along microtubules through the cytoplasm and passes through nuclear pores into the nucleus. These findings validate TM4SF1 as an attractive candidate for cancer therapy with antibody-bound toxins that have the capacity to react with either cytoplasmic or nuclear targets in tumor cells or tumor-associated vascular endothelium. - Highlights: • Anti-TM4SF1 antibody 8G4 was efficiently taken up by cultured endothelial cells. • TM4SF1–8G4 internalization is dynamin-dependent but clathrin-independent. • TM4SF1–8G4 complexes internalize along microtubules to reach the perinuclear region. • Internalized TM4SF1–8G4 complexes pass through nuclear pores into the nucleus. • TM4SF1 is an attractive candidate for ADC cancer therapy.« less

High-spin structure, K isomers, and state mixing in the neutron-rich isotopes 173Tm and 175Tm

NASA Astrophysics Data System (ADS)

Hughes, R. O.; Lane, G. J.; Dracoulis, G. D.; Byrne, A. P.; Nieminen, P. H.; Watanabe, H.; Carpenter, M. P.; Chowdhury, P.; Janssens, R. V. F.; Kondev, F. G.; Lauritsen, T.; Seweryniak, D.; Zhu, S.

2012-11-01

High-spin states in the odd-proton thulium isotopes 173Tm and 175Tm have been studied using deep-inelastic reactions and γ-ray spectroscopy. In 173Tm, the low-lying structure has been confirmed and numerous new states have been identified, including a three-quasiparticle Kπ= 19/2- isomer with a lifetime of τ=360(100) ns at 1906 keV and a five-quasiparticle Kπ=35/2- isomer with a lifetime of τ= 175(40) ns at 4048 keV. The Kπ=35/2- state is interpreted as a t-band configuration that shows anomalously fast decays. In 175Tm, the low-lying structure has been reevaluated, a candidate state for the 9/2-[514] orbital has been identified at 1175 keV, and the 7/2-[523] bandhead has been measured to have a lifetime of τ= 460(50) ns. Newly identified high-K structures in 175Tm include a Kπ=15/2- isomer with a lifetime of τ= 64(3) ns at 947 keV and a Kπ= 23/2+ isomer with a lifetime of τ= 30(20) μs at 1518 keV. The Kπ=15/2- isomer shows relatively enhanced decays to the 7/2-[523] band that can be explained by chance mixing with the 15/2- member of the 7/2- band. Multiquasiparticle calculations have been performed for 173Tm and 175Tm, the results of which compare well with the experimentally observed high-spin states.

A Review of "Integrity[TM]"

ERIC Educational Resources Information Center

Veldkamp, Bernard P.

2008-01-01

Integrity[TM], an online application for testing both the statistical integrity of the test and the academic integrity of the examinees, was evaluated for this review. Program features and the program output are described. An overview of the statistics in Integrity[TM] is provided, and the application is illustrated with a small simulation study.…

Diode pumped tunable lasers based on Tm:CaF2 and Tm:Ho:CaF2 ceramics

NASA Astrophysics Data System (ADS)

Šulc, Jan; Němec, Michal; Jelinková, Helena; Doroshenko, Maxim E.; Fedorov, Pavel P.; Osiko, Vyacheslav V.

2014-02-01

The Tm:CaF2 (4% of TmF3) and Tm:Ho:CaF2 (2% of TmF3, 0.3% of HoF3) ceramics, prepared using hot pressing, and hot formation technique had been used as an active medium of diode pumped mid-infrared tunable laser. A fibre (core diameter 400 μm, NA = 0.22) coupled laser diode (LIMO, HLU30F400-790) was used to longitudinal pumping. The laser diode was operating in the pulsed regime (6 ms pulse length, 10 Hz repetition rate). The duty-cycle 6% ensures a low thermal load even under the maximum diode pumping power amplitude 25W (ceramics samples were only air-cooled). The laser diode emission wavelength was 786 nm. The 80mm long semi-hemispherical laser resonator consisted of a flat pumping mirror (HR @ 1.85 - 2.15 μm, HT @ 0.78 μm) and a curved (r = 150mm) output coupler with a reflectivity of ˜ 98% @ 1.85 - 2.0 μm for Tm:CaF2 laser or ˜ 99.5% @ 2.0 - 2.15 μm for Ho:Tm:CaF2. Tuning of the laser was accomplished by using a birefringent filter (single 1.5mm thick quartz plate) placed inside the optical resonator at the Brewster angle. Both samples offered broad and smooth tuning possibilities in mid-IR spectral range and the lasers were continuously tunable over ˜ 100 nm. The obtained Tm:CaF2 tunability ranged from 1892 to 1992nm (the maximum output energy 1.8mJ was reached at 1952nm for absorbed pumping energy 78 mJ). In case of Tm:Ho:CaF2 laser tunability from 2016 to 2111nm was reached (the maximum output energy 1.5mJ was reached at 2083nm for absorbed pumping energy 53 mJ). Both these material are good candidates for a future investigation of high energy, ultra-short, laser pulse generation.

Measurements of the 169Tm(n ,2 n )168Tm cross section from threshold to 15 MeV

NASA Astrophysics Data System (ADS)

Soter, J.; Bhike, M.; Finch, S. W.; Krishichayan, Tornow, W.

2017-12-01

Measurements of the 169Tm(n ,2 n )168Tm cross section have been performed via the activation technique at 13 energies between 8.5 and 15.0 MeV. The purpose of this comprehensive data set is to provide an alternative diagnostic tool for obtaining subtle information on the neutron energy distribution produced in inertial confinement deuterium-tritium fusion experiments at the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory. The 169Tm(n ,2 n )168Tm reaction not only provides the primary 14-MeV neutron fluence, but also the important down-scattered neutron fluence, the latter providing information on the density achieved in the deuterium-tritium plasma during a laser shot.

Measurements of the Tm 169 ( n , 2 n ) Tm 168 cross section from threshold to 15 MeV

DOE PAGES

Soter, J.; Bhike, M.; Finch, S. W.; ...

2017-12-27

Measurements of the 169Tm(n,2n) 168Tm cross section have been performed via the activation technique at 13 energies between 8.5 and 15.0 MeV. The purpose of this comprehensive data set is to provide an alternative diagnostic tool for obtaining subtle information on the neutron energy distribution produced in inertial confinement deuterium-tritium fusion experiments at the National Ignition Facility (NIF) at Lawrence Livermore National Laboratory. In conclusion, the 169Tm(n,2n) 168Tm reaction not only provides the primary 14-MeV neutron fluence, but also the important down-scattered neutron fluence, the latter providing information on the density achieved in the deuterium-tritium plasma during a laser shot.

Growth and spectral properties of Tm:BaY2F8 crystals with different Tm3+ concentration

NASA Astrophysics Data System (ADS)

Liu, Wang; Li, Chun; Xu, Jialin; Zhou, Yao; Xie, Huishuang; Gao, Meiling; Yin, Ru; Zheng, Dongyang; Lin, Hai; Liu, Jinghe; Zeng, Fanming

2016-01-01

Tm3+:BaY2F8 (Tm:BYF) laser crystals with different doping concentrations were successfully grown by Czochralski method. The optimal growth parameters obtained are as follows: the pulling rate is 0.5 mm/h; the rotation speed is 5 rpm; the cooling rate is 10°C/h. Phase composition, absorption spectra, and fluorescence properties of crystals were studied by XRD and spectral methods. XRD analysis indicates that the crystal belongs to monoclinic system with the C2/ m space group. The lattice parameters were calculated and the anisotropy of the crystals was studied, confirming that the a axis is the best growth direction. The absorption peaks around 790 nm became larger with increase of Tm3+ concentration. The cross section of 15% Tm:BYF crystal around 791 nm is 9.47 × 10-21 cm2. The 10% Tm:BYF crystal has the strongest emission peak around 1879.6 nm with the FWHM of 79 nm and the emission cross-section of 2.13 × 10-21 cm2, which is favorable for the 1.88 μm laser output.

Registratiom of TM data to digital elevation models

NASA Technical Reports Server (NTRS)

1984-01-01

Several problems arise when attempting to register LANDSAT thematic mapper data to U.S. B Geological Survey digital elevation models (DEMs). The TM data are currently available only in a rotated variant of the Space Oblique Mercator (SOM) map projection. Geometric transforms are thus; required to access TM data in the geodetic coordinates used by the DEMs. Due to positional errors in the TM data, these transforms require some sort of external control. The spatial resolution of TM data exceeds that of the most commonly DEM data. Oversampling DEM data to TM resolution introduces systematic noise. Common terrain processing algorithms (e.g., close computation) compound this problem by acting as high-pass filters.

Assessment of wetland productive capacity from a remote-sensing-based model - A NASA/NMFS joint research project

NASA Technical Reports Server (NTRS)

Butera, M. K.; Frick, A. L.; Browder, J.

1983-01-01

NASA and the U.S. National Marine Fisheries Service have undertaken the development of Landsat Thematic Mapper (TM) technology for the evaluation of the usefulness of wetlands to estuarine fish and shellfish production. Toward this end, a remote sensing-based Productive Capacity model has been developed which characterizes the biological and hydrographic features of a Gulf Coast Marsh to predict detrital export. Regression analyses of TM simulator data for wetland plant production estimation are noted to more accurately estimate the percent of total vegetative cover than biomass, indicating that a nonlinear relationship may be involved.

NASA Langley and NLR Research of Distributed Air/Ground Traffic Management

NASA Technical Reports Server (NTRS)

Ballin, Mark G.; Hoekstra, Jacco M.; Wing, David J.; Lohr, Gary W.

2002-01-01

Distributed Air/Ground Traffic Management (DAG-TM) is a concept of future air traffic operations that proposes to distribute information, decision-making authority, and responsibility among flight crews, the air traffic service provider, and aeronautical operational control organizations. This paper provides an overview and status of DAG-TM research at NASA Langley Research Center and the National Aerospace Laboratory of The Netherlands. Specific objectives of the research are to evaluate the technical and operational feasibility of the autonomous airborne component of DAG-TM, which is founded on the operational paradigm of free flight. The paper includes an overview of research approaches, the airborne technologies under development, and a summary of experimental investigations and findings to date. Although research is not yet complete, these findings indicate that free flight is feasible and will significantly enhance system capacity and safety. While free flight cannot alone resolve the complex issues faced by those modernizing the global airspace, it should be considered an essential part of a comprehensive air traffic management modernization activity.

Optically Based Flame Detection in the NASA Langley 8-ft High- Temperature Wind Tunnel

NASA Technical Reports Server (NTRS)

Borg, Stephen E.

2005-01-01

Two optically based flame-detection systems have been developed for use in NASA Langley's 8-Foot High-Temperature Tunnel (8-ft HTT). These systems are used to detect the presence and stability of the main-burner and pilot-level flames during facility operation. System design considerations will be discussed, and a detailed description of the system components and circuit diagrams will be provided in the Appendices of this report. A more detailed description of the manufacturing process used in the fabrication of the fiber-optic probes is covered in NASA TM-2001-211233.

NASA Technologies for Product Identification

NASA Technical Reports Server (NTRS)

Schramm, Fred, Jr.

2006-01-01

Since 1975 bar codes on products at the retail counter have been accepted as the standard for entering product identity for price determination. Since the beginning of the 21st century, the Data Matrix symbol has become accepted as the bar code format that is marked directly on a part, assembly or product that is durable enough to identify that item for its lifetime. NASA began the studies for direct part marking Data Matrix symbols on parts during the Return to Flight activities after the Challenger Accident. Over the 20 year period that has elapsed since Challenger, a mountain of studies, analyses and focused problem solutions developed by and for NASA have brought about world changing results. NASA Technical Standard 6002 and NASA Handbook 6003 for Direct Part Marking Data Matrix Symbols on Aerospace Parts have formed the basis for most other standards on part marking internationally. NASA and its commercial partners have developed numerous products and methods that addressed the difficulties of collecting part identification in aerospace operations. These products enabled the marking of Data Matrix symbols in virtually every situation and the reading of symbols at great distances, severe angles, under paint and in the dark without a light. Even unmarkable delicate parts now have a process to apply a chemical mixture called NanocodesTM that can be converted to a Data Matrix. The accompanying intellectual property is protected by 10 patents, several of which are licensed. Direct marking Data Matrix on NASA parts virtually eliminates data entry errors and the number of parts that go through their life cycle unmarked, two major threats to sound configuration management and flight safety. NASA is said to only have people and stuff with information connecting them. Data Matrix is one of the most significant improvements since Challenger to the safety and reliability of that connection. This presentation highlights the accomplishments of NASA in its efforts to develop

Results of 17 Independent Geopositional Accuracy Assessments of Earth Satellite Corporation's GeoCover Landsat Thematic Mapper Imagery. Geopositional Accuracy Validation of Orthorectified Landsat TM Imagery: Northeast Asia

NASA Technical Reports Server (NTRS)

Smith, Charles M.

2003-01-01

This report provides results of an independent assessment of the geopositional accuracy of the Earth Satellite (EarthSat) Corporation's GeoCover, Orthorectified Landsat Thematic Mapper (TM) imagery over Northeast Asia. This imagery was purchased through NASA's Earth Science Enterprise (ESE) Scientific Data Purchase (SDP) program.

Research and Development of High Energy 2 - Micron Lasers Based on TM: Doped Ceramic Laser Gain Media and TM: Doped Optical Fibers

DTIC Science & Technology

2016-07-20

AFRL-AFOSR-VA-TR-2016-0257 RESEARCH AND DEVELOPMENT OF HIGH ENERGY 2 - MICRON LASERS BASED ON TM: DOPED CERAMIC LASER GAIN MEDIA AND TM: DOPED...2010 to 01/03/2016 4. TITLE AND SUBTITLE RESEARCH AND DEVELOPMENT OF HIGH ENERGY 2 - MICRON LASERS BASED ON TM: DOPED CERAMIC LASER GAIN MEDIA AND...NOTES 14. ABSTRACT Our research and development of 2-μm femtosecond lasers has included development of mode-locked Tm:fiber lasers , super-continuum

IHC-TM connect-disconnect and efferent control V.

PubMed

Crane, H D

1982-07-01

Four previous papers in this series have explored how the idea of a set of disconnected inner hair cells (IHCs) that can "impact" the tectorial membrane (TM) is consistent with psychophysical data. This paper extends the model and explores the potential for mechanical interaction between the IHCs and outer hair cells (OHCs). In particular, it is speculated that the advantage of IHC-TM disconnect is extended dynamic range, and that movement of the movement of the OHCs and TM, under efferent control, constitutes a mechanical servo system for adjusting IHC-TM spacing along the cochlear partition to achieve this extended range.

Monitoring the Mesoamerican Biological Corridor: A NASA/CCAD Cooperative Research Project

NASA Technical Reports Server (NTRS)

Sever, Thomas; Irwin, Daniel; Sader, Steven A.; Saatchi, Sassan

2004-01-01

To foster scientific cooperation under a Memorandum of Understanding between NASA and the Central American countries, the research project developed regional databases to monitor forest condition and environmental change throughout the region. Of particular interest is the Mesoamerican Biological Corridor (MBC), a chain of protected areas and proposed conservation areas that will link segments of natural habitats in Central America from the borders of northern Columbia to southern Mexico. The first and second year of the project focused on the development of regional satellite databases (JERS-IC, MODIS, and Landsat-TM), training of Central American cooperators and forest cover and change analysis. The three regional satellite mosaics were developed and distributed on CD-ROM to cooperators and regional outlets. Four regional remote sensing training courses were conducted in 3 countries including participants from all 7 Central American countries and Mexico. In year 3, regional forest change assessment in reference to Mesoamerican Biological Corridor was completed and land cover maps (from Landsat TM) were developed for 7 Landsat scenes and accuracy assessed. These maps are being used to support validation of MODIS forest/non forest maps and to examine forest fragmentation and forest cover change in selected study sites. A no-cost time extension (2003-2004) allowed the completion of an M.S. thesis by a Costa Rican student and preparation of manuscripts for future submission to peer-reviewed outlets. Proposals initiated at the end of the project have generated external funding from the U.S. Forest Service (to U. Maine), NASA-ESSF (Oregon State U.) and from USAID and EPA (to NASA-MSFC-GHCC) to test MODIS capabilities to detect forest change; conduct literature review on biomass estimation and carbon stocks and develop a regional remote sensing monitoring center in Central America. The success of the project has led to continued cooperation between NASA, other federal

Quasi four-level Tm:LuAG laser

NASA Technical Reports Server (NTRS)

Jani, Mahendra G. (Inventor); Barnes, Norman P. (Inventor); Hutcheson, Ralph L. (Inventor); Rodriguez, Waldo J. (Inventor)

1997-01-01

A quasi four-level solid-state laser is provided. A laser crystal is disposed in a laser cavity. The laser crystal has a LuAG-based host material doped to a final concentration between about 2% and about 7% thulium (Tm) ions. For the more heavily doped final concentrations, the LuAG-based host material is a LuAG seed crystal doped with a small concentration of Tm ions. Laser diode arrays are disposed transversely to the laser crystal for energizing the Tm ions.

Compact, highly efficient, single-frequency 25W, 2051nm Tm fiber-based MOPA for CO2 trace-gas laser space transmitter

NASA Astrophysics Data System (ADS)

Engin, Doruk; Chuang, Ti; Litvinovitch, Slava; Storm, Mark

2017-08-01

Fibertek has developed and demonstrated an ideal high-power; low-risk; low-size, weight, and power (SWaP) 2051 nm laser design meeting the lidar requirements for satellite-based global measurement of carbon dioxide (CO2). The laser design provides a path to space for either a coherent lidar approach being developed by NASA Jet Propulsion Laboratory (JPL)1,2 or an Integrated Path Differential Lidar (IPDA) approach developed by Harris Corp using radio frequency (RF) modulation and being flown as part of a NASA Earth Venture Suborbital Mission—NASA's Atmospheric Carbon and Transport - America.3,4 The thulium (Tm) fiber laser amplifies a <500 kHz linewidth distributed feedback (DFB) laser up to 25 W average power in a polarization maintaining (PM) fiber. The design manages and suppresses all deleterious non-linear effects that can cause linewidth broadening or amplified spontaneous emission (ASE) and meets all lidar requirements. We believe the core laser components, architecture, and design margins can support a coherent or IPDA lidar 10-year space mission. With follow-on funding Fibertek can adapt an existing space-based Technology Readiness Level 6 (TRL-6), 20 W erbium fiber laser package for this Tm design and enable a near-term space mission with an electrical-to-optical (e-o) efficiency of <20%. A cladding-pumped PM Tm fiber-based amplifier optimized for high efficiency and high-power operation at 2051 nm is presented. The two-stage amplifier has been demonstrated to achieve 25 W average power and <16 dB polarization extinction ratio (PER) out of a single-mode PM fiber using a <500 kHz linewidth JPL DFB laser5-7 and 43 dB gain. The power amplifier's optical conversion efficiency is 53%. An internal efficiency of 58% is calculated after correcting for passive losses. The two-stage amplifier sustains its highly efficient operation for a temperature range of 5-40°C. The absence of stimulated Brillouin scattering (SBS) for the narrow linewidth amplification shows

LaRC(TM)-IA Copolyimides

NASA Technical Reports Server (NTRS)

St. Clair, Terry L.; Chang, Alice C.

1995-01-01

Copolyimides modified versions of LaRC(TM)-IA thermoplastic polyimide formulated by incorporating moieties of 3,3',4,4'-benzophenonetetracarboxylic dianhydride (BTDA) and, alternatively, isophthaloyldiphthalic anhydride (IDPA) into LaRC(TM)-IA polymer backbones. Exhibit higher glass-transition temperatures and retain greater fractions of lower-temperature shear moduli at higher temperatures. Copolyimides spun into fibers or used as adhesives, molding powders, or matrix resins in many applications, especially in fabrication of strong, lightweight structural components of aircraft.

Blue and white light emission in Tm3+ and Tm3+/Dy3+ doped zinc phosphate glasses upon UV light excitation

NASA Astrophysics Data System (ADS)

Meza-Rocha, A. N.; Speghini, A.; Lozada-Morales, R.; Caldiño, U.

2016-08-01

A spectroscopic study based on photoluminescence spectra and decay time profiles in Tm3+ and Tm3+/Dy3+ doped Zn(PO3)2 glasses is reported. The Tm3+ doped Zn(PO3)2 glass, upon 357 nm excitation, exhibits blue emission with CIE1931 chromaticity coordinates, x = 0.157 and y = 0.030, and color purity of about 96%. Under excitations at 348, 352 and 363 nm, which match with the emissions of AlGaN and GaN based LEDs, the Tm3+/Dy3+ co-doped Zn(PO3)2 glass displays natural white, bluish white and cool white overall emissions, with correlated color temperature values of 4523, 10700 and 7788 K, respectively, depending strongly on the excitation wavelength. The shortening of the Dy3+ emission decay time in presence of Tm3+ suggests that Dy3+→Tm3+ non-radiative energy transfer occurs. By using the Inokuti-Hirayama model, it is inferred that an electric quadrupole-quadrupole interaction might be the dominant mechanism involved in the energy transfer. The efficiency and probability of this energy transfer are 0.12 and 126.70 s-1, respectively.

Multi-Instrument Tools and Services to Access NASA Earth Science Data from the GSFC Earth Sciences Data and Information Services Center

NASA Technical Reports Server (NTRS)

Kempler, Steve; Leptoukh, Greg; Lynnes, Chris

2010-01-01

The presentation purpose is to describe multi-instrument tools and services that facilitate access and usability of NASA Earth science data at Goddard Space Flight Center (GSFC). NASA's Earth observing system includes 14 satellites. Topics include EOSDIS facilities and system architecture, and overview of GSFC Earth Science Data and Information Services Center (GES DISC) mission, Mirador data search, Giovanni, multi-instrument data exploration, Google Earth[TM], data merging, and applications.

Ends of the line for tmRNA-SmpB

DOE PAGES

Hudson, Corey M.; Lau, Britney Y.; Williams, Kelly P.

2014-08-13

Genes for the RNA tmRNA and protein SmpB, partners in the trans-translation process that rescues stalled ribosomes, have previously been found in all bacteria and some organelles. We validate recent identification of tmRNA homologs in oomycete mitochondria by finding partner genes from oomycete nuclei that target SmpB to the mitochondrion. Exhaustive search now identifies a small number of complete, often highly derived, bacterial genomes that appear to lack a functional copy of one or the other partner gene (but not both). Three groups with reduced genomes have lost the central loop of SmpB, which is thought to improve alanylation andmore » EF-Tu activation: Carsonella, Hodgkinia and the hemplasmas (hemotropic Mycoplasma). Carsonella has also lost the SmpB C-terminal tail, thought to stimulate the decoding center of the ribosome. Carsonella moreover exhibits gene overlap such that tmRNA maturation should produce a non-stop smpB mRNA, and one isolate exhibits complete degradation of the tmRNA gene yet its smpB shows no evidence for relaxed selective constraint. After loss of the SmpB central loop in the hemoplasmas, a subclade apparently lost tmRNA. At least some of the tmRNA/SmpB-deficient strains appear to further lack the ArfA and ArfB backup systems for ribosome rescue. The most frequent neighbors of smpB are the tmRNA gene, a ratA/rnfH unit, and the gene for RNaseR, a known physical and functional partner of tmRNA-SmpB. The tmRNA Website has moved and been updated, adding an SmpB sequence database (http://bioinformatics.sandia.gov/tmrna).« less

Interplay between magnetic order at Mn and Tm sites alongside the structural distortion in multiferroic films of o -TmMn O3

NASA Astrophysics Data System (ADS)

Windsor, Y. W.; Ramakrishnan, M.; Rettig, L.; Alberca, A.; Bothschafter, E. M.; Staub, U.; Shimamoto, K.; Hu, Y.; Lippert, T.; Schneider, C. W.

2015-06-01

We employ resonant soft x-ray diffraction to individually study the magnetic ordering of the Mn and the Tm sublattices in single-crystalline films of orthorhombic (o -) TmMn O3 . The same magnetic ordering wave vector of (0 q 0 ) with q ≈0.46 is found for both ionic species, suggesting that the familiar antiferromagnetic order of the Mn ions induces a magnetic order on the Tm unpaired 4 f electrons. Indeed, intensity variations of magnetic reflections with temperature corroborate this scenario. Calculated magnetic fields at the Tm sites are used as a model magnetic structure for the Tm, which correctly predicts intensity variations at the Tm resonance upon azimuthal rotation of the sample. The model allows ruling out a b c -cycloid modulation of the Mn ions as the cause for the incommensurate ordering, as found in TbMn O3 . The structural distortion, which occurs in the ferroelectric phase below TC, was followed through nonresonant diffraction of structural reflections forbidden by the high-temperature crystal symmetry. The (0 q 0 ) magnetic reflection appears at the Mn resonance well above TC, indicating that this reflection is sensitive also to the intermediate sinusoidal magnetic phase. The model presented suggests that the Tm 4 f electrons are polarized well above the ferroelectric transition and are possibly not affected by the transition at TC. The successful description of the induced order observed at the Tm resonance is a promising example for future element-selective studies in which "spectator" ions may allow access to previously unobtainable information about other constituent ions.

Investigations of LRE-HRE-TM thin films for hybrid recording

NASA Astrophysics Data System (ADS)

Li, Zuoyi; Cheng, Xiaomin; Jin, Fang; Li, Zhen; Lin, Gengqi; Yang, Xiaofei

2005-09-01

Light rare earth-heavy rare earth-transition metal (LRE-HRE-TM) thin films are a kind of important recording media. A lot of researches have been carried out on the LRE-HRE-TM thin films to improve its properties for data storage application and fruitful results have been achieved. This report gives a glance on the evolution of the research on LRE-HRE-TM recording media. At the same time, combined with the hybrid recording technology, some experimental results obtained on LRE-HRE-TM recording media are discussed, which suggest the promising prospect of the LRE-HRE-TM media in hybrid recording application.

"Festival of Flight Special": Opening Space for Next Generation Explorers. NASA CONNECT[TM]. [Videotape].

ERIC Educational Resources Information Center

National Aeronautics and Space Administration, Hampton, VA. Langley Research Center.

The National Aeronautics and Space Administration's (NASA) Space Launch Initiative (SLI) Program will ultimately move from the explorations of the Mercury, Gemini, Apollo, and Space Shuttle missions to a new period of pioneering in which people and businesses are more routinely traveling, working, and living in space. (Author/NB)

Lessons Learned from NASA UAV Science Demonstration Program Missions

NASA Technical Reports Server (NTRS)

Wegener, Steven S.; Schoenung, Susan M.

2003-01-01

During the summer of 2002, two airborne missions were flown as part of a NASA Earth Science Enterprise program to demonstrate the use of uninhabited aerial vehicles (UAVs) to perform earth science. One mission, the Altus Cumulus Electrification Study (ACES), successfully measured lightning storms in the vicinity of Key West, Florida, during storm season using a high-altitude Altus(TM) UAV. In the other, a solar-powered UAV, the Pathfinder Plus, flew a high-resolution imaging mission over coffee fields in Kauai, Hawaii, to help guide the harvest.

Measurements of the 169Tm(n,2n)168Tm cross section between 9.0 and 17.5 MeV

NASA Astrophysics Data System (ADS)

Soter, J.; Bhike, Megha; Krishichayan, Fnu; Finch, S. W.; Tornow, W.

2016-09-01

Measurements of the 169Tm(n,2n)168Tm cross section have been performed in 0.5 MeV intervals for neutron energies ranging from 9.0 MeV to 17.5 MeV in order to resolve discrepancies in the current literature data. The neutron activation technique was used with 90Zr and 197Au as monitor foils. After irradiation, de-excitation gamma rays were recorded off-line with High-Purity Germanium (HPGE) detectors in TUNL's Low-Background Counting Facility. In addition, data for the 169Tm(n,3n)167Tm reaction have also been obtained from 15.5 MeV to 17.5 MeV. The results of these measurements provide the basis for investigating properties of the interial confinement fusion plasma in deuterium-tritium (DT) capsules at the National Ignition Facility located at Lawrence Livermore National Laboratory.

Tm:germanate Fiber Laser: Tuning And Q-switching

NASA Technical Reports Server (NTRS)

Barnes, Norman P.; Walsh, Brian M.; Reichle, Donald J.; DeYoung, R. J.; Jiang, Shibin

2007-01-01

A Tm:germanate fiber laser produced >0.25 mJ/pulse in a 45 ns pulse. It is capable of producing multiple Q-switched pulses from a single p ump pulse. With the addition of a diffraction grating, Tm:germanate f iber lasers produced a wide, but length dependent, tuning range. By s electing the fiber length, the tuning range extends from 1.88 to 2.04 ?m. These traits make Tm:germanate lasers suitable for remote sensin g of water vapor.

Efficient Cryogenic Near-Infrared Tm: YLF Laser

DTIC Science & Technology

2016-12-22

pumped at 781.5 nm and operated at 816 nm. Although Tm:YLF has lower nonradiative decay rate than Tm:YAG, residual population trapping still affects...mitigated by cryogenic cooling, use of a YLF crystal host to reduce nonradiative decay rates and the use of a dual-wavelength resonator to

Social Stories[TM]: A Possible Theoretical Rationale

ERIC Educational Resources Information Center

Reynhout, Georgina; Carter, Mark

2011-01-01

Social Stories[TM] are an intervention widely used with individuals with autism spectrum disorders (ASD). This paper discusses a possible theoretical rationale that might account for the purported efficacy of Social Stories[TM]. Attributes of individuals with ASD in relation to Social Story intervention including difficulties with theory of mind…

LibQUAL+[TM]: A Methodological Suite; Reliability and Structure of LibQUAL+[TM] Scores: Measuring Perceived Library Service Quality; Score Norms for Improving Library Service Quality: A LibQUAL+[TM] Study; ARL Index and Other Validity Correlates of LibQUAL+[TM] Scores.

ERIC Educational Resources Information Center

Heath, Fred M.; Thompson, Bruce; Cook, Colleen; Thompson, Russel L.; Kyrillidou, Martha

2002-01-01

Includes four articles that discuss LibQUAL+[TM], a collaborative effort of the Association of Research Libraries and Texas A&M University responding to the need for greater accountability in measuring the delivery of library services to research library users. Discusses the reliability of LibQUAL+[TM] scores in measuring perceived library…

Passively Q-switched Tm:BaY2F8 lasers

NASA Astrophysics Data System (ADS)

Yu, Haohai; Veronesi, Stefano; Mateos, Xavier; Petrov, Valentin; Griebner, Uwe; Parisi, Daniela; Tonelli, Mauro

2013-07-01

We demonstrate passive Q-switching (PQS) of the Tm-doped BaY2F8 (Tm:BYF) laser for the first time. The Tm:BYF laser is diode-pumped using an L-shaped hemispherical resonator. In the cw regime, the maximum output power with an 18% Tm-doped BYF crystal reached 1.12 W at ~1920 nm for an absorbed pump power of 3.06 W. In the PQS regime, maximum pulse energy (720 μJ) and peak power (17.1 kW) were obtained with an 8% Tm-doped BYF crystal and a Cr:ZnS saturable absorber with 92% low-signal transmission, again near 1920 nm, for a pulse width of ~40 ns and a repetition rate of 50 Hz.

Consistency of L4 TM absolute calibration with respect to the L5 TM sensor based on near-simultaneous image acquisition

NASA Astrophysics Data System (ADS)

Chander, Gyanesh; Helder, Dennis L.; Malla, Rimy; Micijevic, Esad; Mettler, Cory J.

2007-09-01

The Landsat archive provides more than 35 years of uninterrupted multispectral remotely sensed data of Earth observations. Since 1972, Landsat missions have carried different types of sensors, from the Return Beam Vidicon (RBV) camera to the Enhanced Thematic Mapper Plus (ETM+). However, the Thematic Mapper (TM) sensors on Landsat 4 (L4) and Landsat 5 (L5), launched in 1982 and 1984 respectively, are the backbone of an extensive archive. Effective April 2, 2007, the radiometric calibration of L5 TM data processed and distributed by the U.S. Geological Survey (USGS) Center for Earth Resources Observation and Science (EROS) was updated to use an improved lifetime gain model, based on the instrument's detector response to pseudo-invariant desert site data and cross-calibration with the L7 ETM+. However, no modifications were ever made to the radiometric calibration procedure of the Landsat 4 (L4) TM data. The L4 TM radiometric calibration procedure has continued to use the Internal Calibrator (IC) based calibration algorithms and the post calibration dynamic ranges, as previously defined. To evaluate the "current" absolute accuracy of these two sensors, image pairs from the L5 TM and L4 TM sensors were compared. The number of coincident image pairs in the USGS EROS archive is limited, so the scene selection for the cross-calibration studies proved to be a challenge. Additionally, because of the lack of near-simultaneous images available over well-characterized and traditionally used calibration sites, alternate sites that have high reflectance, large dynamic range, high spatial uniformity, high sun elevation, and minimal cloud cover were investigated. The alternate sites were identified in Yuma, Iraq, Egypt, Libya, and Algeria. The cross-calibration approach involved comparing image statistics derived from large common areas observed eight days apart by the two sensors. This paper summarizes the average percent differences in reflectance estimates obtained between the

Consistency of L4 TM absolute calibration with respect to the L5 TM sensor based on near-simultaneous image acquisition

USGS Publications Warehouse

Chander, G.; Helder, D.L.; Malla, R.; Micijevic, E.; Mettler, C.J.

2007-01-01

The Landsat archive provides more than 35 years of uninterrupted multispectral remotely sensed data of Earth observations. Since 1972, Landsat missions have carried different types of sensors, from the Return Beam Vidicon (RBV) camera to the Enhanced Thematic Mapper Plus (ETM+). However, the Thematic Mapper (TM) sensors on Landsat 4 (L4) and Landsat 5 (L5), launched in 1982 and 1984 respectively, are the backbone of an extensive archive. Effective April 2, 2007, the radiometric calibration of L5 TM data processed and distributed by the U.S. Geological Survey (USGS) Center for Earth Resources Observation and Science (EROS) was updated to use an improved lifetime gain model, based on the instrument's detector response to pseudo-invariant desert site data and cross-calibration with the L7 ETM+. However, no modifications were ever made to the radiometric calibration procedure of the Landsat 4 (L4) TM data. The L4 TM radiometric calibration procedure has continued to use the Internal Calibrator (IC) based calibration algorithms and the post calibration dynamic ranges, as previously defined. To evaluate the "current" absolute accuracy of these two sensors, image pairs from the L5 TM and L4 TM sensors were compared. The number of coincident image pairs in the USGS EROS archive is limited, so the scene selection for the cross-calibration studies proved to be a challenge. Additionally, because of the lack of near-simultaneous images available over well-characterized and traditionally used calibration sites, alternate sites that have high reflectance, large dynamic range, high spatial uniformity, high sun elevation, and minimal cloud cover were investigated. The alternate sites were identified in Yuma, Iraq, Egypt, Libya, and Algeria. The cross-calibration approach involved comparing image statistics derived from large common areas observed eight days apart by the two sensors. This paper summarizes the average percent differences in reflectance estimates obtained between the

Image Analysis via Fuzzy-Reasoning Approach: Prototype Applications at NASA

NASA Technical Reports Server (NTRS)

Dominguez, Jesus A.; Klinko, Steven J.

2004-01-01

A set of imaging techniques based on Fuzzy Reasoning (FR) approach was built for NASA at Kennedy Space Center (KSC) to perform complex real-time visual-related safety prototype tasks, such as detection and tracking of moving Foreign Objects Debris (FOD) during the NASA Space Shuttle liftoff and visual anomaly detection on slidewires used in the emergency egress system for Space Shuttle at the launch pad. The system has also proved its prospective in enhancing X-ray images used to screen hard-covered items leading to a better visualization. The system capability was used as well during the imaging analysis of the Space Shuttle Columbia accident. These FR-based imaging techniques include novel proprietary adaptive image segmentation, image edge extraction, and image enhancement. Probabilistic Neural Network (PNN) scheme available from NeuroShell(TM) Classifier and optimized via Genetic Algorithm (GA) was also used along with this set of novel imaging techniques to add powerful learning and image classification capabilities. Prototype applications built using these techniques have received NASA Space Awards, including a Board Action Award, and are currently being filed for patents by NASA; they are being offered for commercialization through the Research Triangle Institute (RTI), an internationally recognized corporation in scientific research and technology development. Companies from different fields, including security, medical, text digitalization, and aerospace, are currently in the process of licensing these technologies from NASA.

Performance evaluation and geologic utility of LANDSAT 4 TM and MSS scanners

NASA Technical Reports Server (NTRS)

Paley, H. N.

1983-01-01

Experiments using artificial targets (polyethylene sheets) to help calibrate and evaluate atmospheric effects as well as the radiometric precision and spatial characteristics of the NS-001 and TM sensor systems were attempted and show the technical feasibility of using plastic targets for such studies, although weather precluded successful TM data acquisition. Tapes for six LANDSAT 4 TM scenes were acquired and data processing began. Computer enhanced TM simulator and LANDSAT 4 TM data were compared for a porphyry copper deposit in Southern Arizona. Preliminary analyses performed on two TM scenes acquired in the CCT-PT format, show the TM data appear to contain a marked increase in geologically useful information; however, a number of instrumental processing artifacts may well limit the ability of the geologist to fully extract this information.

Spectroscopic and laser characterization of Yb,Tm:KLu(WO4)2 crystal

NASA Astrophysics Data System (ADS)

Loiko, P. A.; Serres, J. M.; Mateos, X.; Demesh, M. P.; Yasukevich, A. S.; Yumashev, K. V.; Petrov, V.; Griebner, U.; Aguiló, M.; Díaz, F.

2016-01-01

We report on a comprehensive spectroscopic and laser characterization of monoclinic Yb,Tm:KLu(WO4)2 crystals. Stimulated-emission cross-section spectra corresponding to the 3F4 → 3H6 transition of Tm3+ ions are determined. The radiative lifetime of the 3F4 state of Tm3+ ions is 0.82 ms. The maximum Yb3+ → Tm3+ energy transfer efficiency is 83.9% for 5 at.% Yb - 8 at.% Tm doping. The fractional heat loading for Yb,Tm:KLu(WO4)2 is 0.45 ± 0.05. Using a hemispherical cavity and 5 at.% Yb - 6 at.% Tm doped crystal, a maximum CW power of 227 mW is achieved at 1.983-2.011 μm with a maximum slope efficiency η = 14%. In the microchip laser set-up, the highest slope efficiency is 20% for a 5 at.% Yb- 8 at.% Tm doped crystal with a maximum output power of 201 mW at 1.99-2.007 μm. Operation of Yb,Tm:KLu(WO4)2 as a vibronic laser emitting at 2.081-2.093 μm is also demonstrated.

Tm-doped TiO2 and Tm2Ti2O7 pyrochlore nanoparticles: enhancing the photocatalytic activity of rutile with a pyrochlore phase.

PubMed

De Los Santos, Desiré M; Navas, Javier; Aguilar, Teresa; Sánchez-Coronilla, Antonio; Fernández-Lorenzo, Concha; Alcántara, Rodrigo; Piñero, Jose Carlos; Blanco, Ginesa; Martín-Calleja, Joaquín

2015-01-01

Tm-doped TiO2 nanoparticles were synthesized using a water-controlled hydrolysis reaction. Analysis was performed in order to determine the influence of the dopant concentration and annealing temperature on the phase, crystallinity, and electronic and optical properties of the resulting material. Various characterization techniques were utilized such as X-ray diffraction, Raman spectroscopy, X-ray photoelectron spectroscopy and UV-vis spectroscopy. For the samples annealed at 773 and 973 K, anatase phase TiO2 was obtained, predominantly internally doped with Tm(3+). ICP-AES showed that a doping concentration of up to 5.8 atom % was obtained without reducing the crystallinity of the samples. The presence of Tm(3+) was confirmed by X-ray photoelectron spectroscopy and UV-vis spectroscopy: the incorporation of Tm(3+) was confirmed by the generation of new absorption bands that could be assigned to Tm(3+) transitions. Furthermore, when the samples were annealed at 1173 K, a pyrochlore phase (Tm2Ti2O7) mixed with TiO2 was obtained with a predominant rutile phase. The photodegradation of methylene blue showed that this pyrochlore phase enhanced the photocatalytic activity of the rutile phase.

Accelerated Math[TM]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2011

2011-01-01

"Accelerated Math"[TM], published by Renaissance Learning, is a software tool used to customize assignments and monitor progress in math for students in grades 1-12. The "Accelerated Math"[TM] software creates individualized assignments aligned with state standards and national guidelines, scores student work, and generates…

Relative radiometric calibration of LANDSAT TM reflective bands

NASA Technical Reports Server (NTRS)

Barker, J. L.

1984-01-01

A common scientific methodology and terminology is outlined for characterizing the radiometry of both TM sensors. The magnitude of the most significant sources of radiometric variability are discussed and methods are recommended for achieving the exceptional potential inherent in the radiometric precision and accuracy of the TM sensors.

Conserved Asp-137 is important for both structure and regulatory functions of cardiac α-tropomyosin (α-TM) in a novel transgenic mouse model expressing α-TM-D137L.

PubMed

Yar, Sumeyye; Chowdhury, Shamim A K; Davis, Robert T; Kobayashi, Minae; Monasky, Michelle M; Rajan, Sudarsan; Wolska, Beata M; Gaponenko, Vadim; Kobayashi, Tomoyoshi; Wieczorek, David F; Solaro, R John

2013-06-07

α-Tropomyosin (α-TM) has a conserved, charged Asp-137 residue located in the hydrophobic core of its coiled-coil structure, which is unusual in that the residue is found at a position typically occupied by a hydrophobic residue. Asp-137 is thought to destabilize the coiled-coil and so impart structural flexibility to the molecule, which is believed to be crucial for its function in the heart. A previous in vitro study indicated that the conversion of Asp-137 to a more typical canonical Leu alters flexibility of TM and affects its in vitro regulatory functions. However, the physiological importance of the residue Asp-137 and altered TM flexibility is unknown. In this study, we further analyzed structural properties of the α-TM-D137L variant and addressed the physiological importance of TM flexibility in cardiac function in studies with a novel transgenic mouse model expressing α-TM-D137L in the heart. Our NMR spectroscopy data indicated that the presence of D137L introduced long range rearrangements in TM structure. Differential scanning calorimetry measurements demonstrated that α-TM-D137L has higher thermal stability compared with α-TM, which correlated with decreased flexibility. Hearts of transgenic mice expressing α-TM-D137L showed systolic and diastolic dysfunction with decreased myofilament Ca(2+) sensitivity and cardiomyocyte contractility without changes in intracellular Ca(2+) transients or post-translational modifications of major myofilament proteins. We conclude that conversion of the highly conserved Asp-137 to Leu results in loss of flexibility of TM that is important for its regulatory functions in mouse hearts. Thus, our results provide insight into the link between flexibility of TM and its function in ejecting hearts.

Conserved Asp-137 Is Important for both Structure and Regulatory Functions of Cardiac α-Tropomyosin (α-TM) in a Novel Transgenic Mouse Model Expressing α-TM-D137L*

PubMed Central

Yar, Sumeyye; Chowdhury, Shamim A. K.; Davis, Robert T.; Kobayashi, Minae; Monasky, Michelle M.; Rajan, Sudarsan; Wolska, Beata M.; Gaponenko, Vadim; Kobayashi, Tomoyoshi; Wieczorek, David F.; Solaro, R. John

2013-01-01

α-Tropomyosin (α-TM) has a conserved, charged Asp-137 residue located in the hydrophobic core of its coiled-coil structure, which is unusual in that the residue is found at a position typically occupied by a hydrophobic residue. Asp-137 is thought to destabilize the coiled-coil and so impart structural flexibility to the molecule, which is believed to be crucial for its function in the heart. A previous in vitro study indicated that the conversion of Asp-137 to a more typical canonical Leu alters flexibility of TM and affects its in vitro regulatory functions. However, the physiological importance of the residue Asp-137 and altered TM flexibility is unknown. In this study, we further analyzed structural properties of the α-TM-D137L variant and addressed the physiological importance of TM flexibility in cardiac function in studies with a novel transgenic mouse model expressing α-TM-D137L in the heart. Our NMR spectroscopy data indicated that the presence of D137L introduced long range rearrangements in TM structure. Differential scanning calorimetry measurements demonstrated that α-TM-D137L has higher thermal stability compared with α-TM, which correlated with decreased flexibility. Hearts of transgenic mice expressing α-TM-D137L showed systolic and diastolic dysfunction with decreased myofilament Ca2+ sensitivity and cardiomyocyte contractility without changes in intracellular Ca2+ transients or post-translational modifications of major myofilament proteins. We conclude that conversion of the highly conserved Asp-137 to Leu results in loss of flexibility of TM that is important for its regulatory functions in mouse hearts. Thus, our results provide insight into the link between flexibility of TM and its function in ejecting hearts. PMID:23609439

Nasa's Land Remote Sensing Plans for the 1980's

NASA Technical Reports Server (NTRS)

Higg, H. C.; Butera, K. M.; Settle, M.

1985-01-01

Research since the launch of LANDSAT-1 has been primarily directed to the development of analysis techniques and to the conduct of applications studies designed to address resource information needs in the United States and in many other countries. The current measurement capabilities represented by MSS, TM, and SIR-A and B, coupled with the present level of remote sensing understanding and the state of knowledge in the discipline earth sciences, form the foundation for NASA's Land Processes Program. Science issues to be systematically addressed include: energy balance, hydrologic cycle, biogeochemical cycles, biological productivity, rock cycle, landscape development, geological and botanical associations, and land surface inventory, monitoring, and modeling. A global perspective is required for using remote sensing technology for problem solving or applications context. A successful model for this kind of activity involves joint research with a user entity where the user provides a test site and ground truth and NASA provides the remote sensing techniques to be tested.

Type II integral membrane protein, TM of J paramyxovirus promotes cell-to-cell fusion.

PubMed

Li, Zhuo; Hung, Cher; Paterson, Reay G; Michel, Frank; Fuentes, Sandra; Place, Ryan; Lin, Yuan; Hogan, Robert J; Lamb, Robert A; He, Biao

2015-10-06

Paramyxoviruses include many important animal and human pathogens. Most paramyxoviruses have two integral membrane proteins: fusion protein (F) and attachment proteins hemagglutinin, hemagglutinin-neuraminidase, or glycoprotein (G), which are critical for viral entry into cells. J paramyxovirus (JPV) encodes four integral membrane proteins: F, G, SH, and transmembrane (TM). The function of TM is not known. In this work, we have generated a viable JPV lacking TM (JPV∆TM). JPV∆TM formed opaque plaques compared with JPV. Quantitative syncytia assays showed that JPV∆TM was defective in promoting cell-to-cell fusion (i.e., syncytia formation) compared with JPV. Furthermore, cells separately expressing F, G, TM, or F plus G did not form syncytia whereas cells expressing F plus TM formed some syncytia. However, syncytia formation was much greater with coexpression of F, G, and TM. Biochemical analysis indicates that F, G, and TM interact with each other. A small hydrophobic region in the TM ectodomain from amino acid residues 118 to 132, the hydrophobic loop (HL), was important for syncytial promotion, suggesting that the TM HL region plays a critical role in cell-to-cell fusion.

Accelerated Reader[TM]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2010

2010-01-01

"Accelerated Reader"[TM] is a guided reading intervention used to supplement regular reading instruction in K-12 classrooms. Its aim is to improve students' reading skills through reading practice and quizzes on the books students read. The "Accelerated Reader"[TM] program calls for students to select and read a book and then…

EMASS (trademark): An expandable solution for NASA space data storage needs

NASA Technical Reports Server (NTRS)

Peterson, Anthony L.; Cardwell, P. Larry

1991-01-01

The data acquisition, distribution, processing, and archiving requirements of NASA and other U.S. Government data centers present significant data management challenges that must be met in the 1990's. The Earth Observing System (EOS) project alone is expected to generate daily data volumes greater than 2 Terabytes (2 x 10(exp 12) Bytes). As the scientific community makes use of this data, their work will result in larger, increasingly complex data sets to be further exploited and managed. The challenge for data storage systems is to satisfy the initial data management requirements with cost effective solutions that provide for planned growth. The expendable architecture of the E-Systems Modular Automated Storage System (EMASS(TM)), a mass storage system which is designed to support NASA's data capture, storage, distribution, and management requirements into the 21st century is described.

Anti-cancer Activity of Novel TM4SF5-Targeting Antibodies through TM4SF5 Neutralization and Immune Cell-Mediated Cytotoxicity

PubMed Central

Ahn, Hye-Mi; Ryu, Jihye; Song, Jin Myeong; Lee, Yunhee; Kim, Hye-Jin; Ko, Dongjoon; Choi, Inpyo; Kim, Sang Jick; Lee, Jung Weon; Kim, Semi

2017-01-01

The transmembrane four L6 family member 5 (TM4SF5) protein is a novel molecular target for the prevention and treatment of hepatocellular carcinoma. TM4SF5 is highly expressed in liver, colon, esophageal, and pancreatic cancers and is implicated in tumor progression. Here, we screened monoclonal antibodies that specifically bound to the extracellular loop 2 (EC2) of TM4SF5 from a phage-displayed murine antibody (single-chain variable fragment; scFv) library. We constructed and characterized chimeric antibodies, Ab27 and Ab79, of scFv fused with Fc domain of human IgG1. The affinity (KD) of Ab27 and Ab79 for soluble EC2 was approximately 9.2 nM and 16.9 nM, respectively, as determined by surface plasmon resonance analysis. Ab27 and Ab79 efficiently bound to native TM4SF5 on the cell surface were internalized into the cancer cells, leading to a decrease in cell surface TM4SF5. Ab27 and Ab79 inhibited the proliferation and invasion of TM4SF5-positive liver and colon cancer cells and reduced FAK and c-Src phosphorylation. Ab27 and Ab79 also enhanced anoikis sensitivity and reduced survivin. Ab27 mediated antibody-dependent cell-mediated cytotoxicity in vitro. Ab27 and Ab79 efficiently inhibited tumor growth in a liver cancer xenograft model. These results strongly support the further development of Ab27 as a novel anti-cancer agent in the clinic. PMID:28255353

Comparison of tunable lasers based on diode pumped Tm-doped crystals

NASA Astrophysics Data System (ADS)

Šulc, Jan; Jelínková, Helena; Koranda, Petr; Černý, Pavel; Jabczyński, Jan K.; Żendzian, Waldemar; Kwiatkowski, Jacek; Urata, Yoshiharu; Higuchi, Mikio

2008-12-01

We report on continuously tunable operation of a diode pumped lasers based on Tm-doped materials, emitting in the 1.8 - 2.μ1 m spectral band. In our study we compare results obtained with three various single crystals doped by Tm3+ ions: Yttrium Aluminum perovskite YAP (YAlO3), Gadolinium orthovanadate GdVO4, and Yttrium Lithium Fluoride YLF (YLiF4). Following samples were available: the 3mm long a-cut crystal rod of Tm:YAP with 4% at. Tm/Y (diameter 3 mm); the 8mm long b-cut crystal rod of Tm:YLF with 3.5% at. Tm/Y (diameter 3 mm); the 2.7mm long a-cut crystal block of Tm:GdVO4 with 2% at. Tm/Gd (crystal face 5×3 mm). For active medium pumping, the laser diode radiation was used. Because the tested samples differs significantly in absorption spectra, two fibre-coupled (core diameter 400 µm) temperature-tuned laser diodes were used: first operating at wavelength 793nm was used for Tm:YAP and Tm:YLF; the second operating at wavelength 802nm was used for Tm:GdVO4. In both cases, the continuous power up to 20W was available for pumping. The diode radiation was focused into the active crystal by two achromatic doublet lenses with the focal length f = 75 mm. The measured radius of pumping beam focus inside the crystal was 260 µm. The longitudinally diode pumped crystals were tested in linear, 80mm long, hemispherical laser cavity. The curved (radius 150mm) output coupler reflectivity was ~ 97 % in range from 1.8 up to 2.1 μm. The pumping flat mirror had maximal reflectivity in this range and it had high transmission around 0.8 μm. A 1.5mm thick birefringent plate made from quartz (Lyot filter) inserted under a Brewster's angle was used as a tuning element. This plate was placed inside the resonator between the crystal and the output coupler. Using Tm:YAP crystal, the maximal output power of 2.8W in this set-up was obtained. The laser could be tuned from 1865nm up to 2036nm with a maximum at 1985 nm. Laser based on Tm:YLF crystal was tunable from 1835nm up to

76 FR 38618 - Proposed Information Collection; Comment Request; StormReadyTM

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-01

... Collection; Comment Request; StormReady\\TM\\, TsunamiReady\\TM\\ and StormReady/TsunamiReady\\TM\\ Application... information collection. The StormReady Program, like the TsunamiReady and StormReady/TsunamiReady programs... certain guidelines that qualify them for StormReady recognition. The full StormReady recognition is not...

GEOMAG[TM] Paradoxes

ERIC Educational Resources Information Center

Defrancesco, Silvia; Logiurato, Fabrizio; Karwasz, Grzegorz

2007-01-01

As often happens, a lot of physics can come out of a toy. What we found interesting is the observation of the magnetic field produced by different configurations built with GEOMAG[TM]. This toy provides small magnetic bars and steel spheres to play with. Amusing 3-D structures can be built; nevertheless, this possibility is not so obvious. Indeed,…

Using the Sonoran Desert test site to monitor the long-term radiometric stability of the Landsat TM/ETM+ and Terra MODIS sensors

USGS Publications Warehouse

Angal, A.; Xiong, X.; Choi, T.; Chander, G.; Wu, A.

2009-01-01

Pseudo-invariant ground targets have been extensively used to monitor the long-term radiometric calibration stability of remote sensing instruments. The NASA MODIS Characterization Support Team (MCST), in collaboration with members from the U.S. Geological Survey (USGS) Earth Resources Observation and Science (EROS) Center, has previously demonstrated the use of pseudo-invariant ground sites for the long-term stability monitoring of Terra MODIS and Landsat 7 ETM+ sensors. This paper focuses on the results derived from observations made over the Sonoran Desert. Additionally, Landsat 5 TM data over the Sonoran Desert site were used to evaluate the temporal stability of this site. Top-ofatmosphere (TOA) reflectances were computed for the closely matched TM, ETM+, and MODIS spectral bands over selected regions of interest. The impacts due to different viewing geometries, or the effect of test site Bi-directional Reflectance Distribution Function (BRDF), are also presented. ?? 2009 SPIE.

Inside Linden Lab: Second Life [TM] for Educators

ERIC Educational Resources Information Center

Atkinson, Tom

2008-01-01

A new culture called Second Life [TM] has emerged that promises innovative strategies for everything from social interactions to business. Some educators believe it may hold new and unique opportunities for teaching and learning. Second Life [TM] (SL) is the creation of Linden Labs, a San Francisco-based corporation defined by its creators as "an…

Landsat-D TM application to porphyry copper exploration

NASA Technical Reports Server (NTRS)

Abrams, M.; Brown, D.; Sadowski, R.; Lepley, L.

1982-01-01

For a number of years Landsat data have been used to locate areas of iron oxide occurrences which might be associated with hydrothermal alteration zones. However, the usefulness of the Landsat data was restricted because of certain limitations of the spectral information provided by Landsat. A new generation multispectral scanner will, therefore, be carried by the fourth Landsat, which is to be launched in July, 1982. This instrument, called the Thematic Mapper (TM), will have seven channels and provide data with 30 m spatial resolution. Two of the spectral channels (1.6 micron and 2.2 micron) should allow detection of hydrous minerals. Possible applications of Landsat-D TM data for copper exploration were studied on the basis of a comparison of Landsat data with simulated TM data acquired using an aircraft scanner instrument. Three porphyr copper deposits in Arizona were selected for the study. It is concluded that the new Landsat-D TM scanner will provide Exploration geologists with a new improved tool for surveying mineral resources on a global basis.

Efficient Q-switched Tm:YAG ceramic slab laser.

PubMed

Zhang, Shuaiyi; Wang, Mingjian; Xu, Lin; Wang, Yan; Tang, Yulong; Cheng, Xiaojin; Chen, Weibiao; Xu, Jianqiu; Jiang, Benxue; Pan, Yubai

2011-01-17

Characteristics of Tm:YAG ceramic for high efficient 2-μm lasers are analyzed. Efficient diode end-pumped continuous-wave and Q-switched Tm:YAG ceramic lasers are demonstrated. At the absorbed pump power of 53.2W, the maximum continuous wave (cw) output power of 17.2 W around 2016 nm was obtained with the output transmission of 5%. The optical conversion efficiency is 32.3%, corresponding to a slope efficiency of 36.5%. For Q-switched operation, the shortest width of 69 ns was achieved with the pulse repetition frequency of 500 Hz and single pulse energy of 20.4 mJ, which indicates excellent energy storage capability of the Tm:YAG ceramic.

Questioning LibQUAL+[TM]: Expanding Its Assessment of Academic Library Effectiveness

ERIC Educational Resources Information Center

Edgar, William B.

2006-01-01

This article examines LibQUAL+[TM]'s instrument, fundamental assumption, and research approach and proposes a functional/technical model of academic library effectiveness. This expanded view of library effectiveness complements LibQUAL+[TM], emphasizing it to be dependent upon users' experience of service delivery, as LibQUAL+[TM] recognizes.…

Spectroscopic, luminescent and laser properties of nanostructured CaF2:Tm materials

NASA Astrophysics Data System (ADS)

Lyapin, A. A.; Fedorov, P. P.; Garibin, E. A.; Malov, A. V.; Osiko, V. V.; Ryabochkina, P. A.; Ushakov, S. N.

2013-08-01

The laser quality transparent СаF2:Tm fluoride ceramics has been prepared by hot forming. Comparative study of absorption and emission spectra of СаF2:Tm (4 mol.% TmF3) ceramic and single crystal samples demonstrated that these materials possess almost identical spectroscopic properties. Laser oscillations of СаF2:Tm ceramics were obtained at 1898 nm under diode pumping, with the slope efficiency of 5.5%. Also, the continuous-wave (CW) laser have been obtained for СаF2:Tm single crystal at 1890 nm pumped by a diode laser was demonstrated.

Plastic Muscles TM as lightweight, low voltage actuators and sensors

NASA Astrophysics Data System (ADS)

Bennett, Matthew; Leo, Donald; Duncan, Andrew

2008-03-01

Using proprietary technology, Discover Technologies has developed ionomeric polymer transducers that are capable of long-term operation in air. These "Plastic Muscle TM" transducers are useful as soft distributed actuators and sensors and have a wide range of applications in the aerospace, robotics, automotive, electronics, and biomedical industries. Discover Technologies is developing novel fabrication methods that allow the Plastic Muscles TM to be manufactured on a commercial scale. The Plastic Muscle TM transducers are capable of generating more than 0.5% bending strain at a peak strain rate of over 0.1 %/s with a 3 V input. Because the Plastic Muscles TM use an ionic liquid as a replacement solvent for water, they are able to operate in air for long periods of time. Also, the Plastic Muscles TM do not exhibit the characteristic "back relaxation" phenomenon that is common in water-swollen devices. The elastic modulus of the Plastic Muscle TM transducers is estimated to be 200 MPa and the maximum generated stress is estimated to be 1 MPa. Based on these values, the maximum blocked force at the tip of a 6 mm wide, 35 mm long actuator is estimated to be 19 mN. Modeling of the step response with an exponential series reveals nonlinearity in the transducers' behavior.

Optical Properties of Tm(3+) Ions in Alkali Germanate Glass

NASA Technical Reports Server (NTRS)

Walsh, Brian M.; Barnes, Norman P.; Reichle, Donald J.; Jiang, Shibin

2006-01-01

Tm-doped alkali germanate glass is investigated for use as a laser material. Spectroscopic investigations of bulk Tm-doped germanate glass are reported for the absorption, emission and luminescence decay. Tm:germanate shows promise as a fiber laser when pumped with 0.792 m diodes because of low phonon energies. Spectroscopic analysis indicates low nonradiative quenching and pulsed laser performance studies confirm this prediction by showing a quantum efficiency of 1.69.

In vitro and in vivo Safety Evaluation of NephureTM

PubMed Central

Cowley, Helena; Yan, Qin; Koetzner, Lee; Dolan, Laurie; Nordwald, Erik; Cowley, Aaron B.

2017-01-01

NephureTM is a proprietary oxalate decarboxylase (OxDC) enzyme being developed as a food ingredient. In this study, the safety of NephureTM was evaluated in a bacterial mutagenicity assay and in a sub-chronic (13-week) oral toxicity study in rats. NephureTM did not show any mutagenic properties in the mutagenicity assay. In the 13-week sub-chronic oral toxicity study in which 10 Sprague Dawley rats per sex were administered 0, 118, 235 and 475 mg/kg bw/day (8260, 16450 and 33,250 Units/kg bw/day, respectively) of NephureTM by gavage, male and female rats did not show any test article-related clinical observations or effects on body weight, body weight gain, food consumption, food efficiency, ophthalmology, functional observational battery parameters or motor activity. Furthermore, there were no changes in coagulation, clinical chemistry, urinalysis or hematology parameters, macroscopic/microscopic findings or organ weights that could be attributed to the test article. Based on these results, NephureTM was not mutagenic and the no-adverse-effect level (NOAEL) in the 13-week study was determined to be 475 mg/kg bw/day (33,250 Units/kg bw/day). Evaluation of the estimated consumption of NephureTM, generation of the metabolite formate, and the current safety studies resulted in a conclusion of a tolerable upper limit of 3450 Units of OxDC activity/day (57.5 Units activity/kg bw/day), when NephureTM is added to food to decrease dietary oxalate. PMID:28322893

TM4SF5-Mediated Roles in the Development of Fibrotic Phenotypes

PubMed Central

Ryu, Jihye

2017-01-01

Transmembrane 4 L six family member 5 (TM4SF5) can form tetraspanin-enriched microdomains (TERMs) on the cell's surface. TERMs contain protein-protein complexes comprised of tetraspanins, growth factor receptors, and integrins. These complexes regulate communication between extracellular and intracellular spaces to control diverse cellular functions. TM4SF5 influences the epithelial-mesenchymal transition (EMT), aberrant multilayer cellular growth, drug resistance, enhanced migration and invasion, circulation through the bloodstream, tumor-initiation property, metastasis, and muscle development in zebrafish. Here, current data on TM4SF5's roles in the development of fibrotic phenotypes are reviewed. TM4SF5 is induced by transforming growth factor β1 (TGFβ1) signaling via a collaboration with epidermal growth factor receptor (EGFR) activation. TM4SF5, by itself or in concert with other receptors, transduces signals intracellularly. In hepatocytes, TM4SF5 expression regulates cell cycle progression, migration, and expression of extracellular matrix components. In CCl4-treated mice, TM4SF5, α-smooth muscle actin (α-SMA), and collagen I expression are observed together along the fibrotic septa regions of the liver. These fibrotic phenotypes are diminished by anti-TM4SF5 reagents, such as a specific small compound [TSAHC, 4′-(p-toluenesulfonylamido)-4-hydroxychalcone] or a chimeric antibody. This review discusses the antifibrotic strategies that target TM4SF5 and its associated protein networks that regulate the intracellular signaling necessary for fibrotic functions of hepatocytes. PMID:28458469

First observation of a negative elastic constant in intermediate valent TmSe

NASA Astrophysics Data System (ADS)

Boppart, H.; Treindl, A.; Wachter, P.; Roth, S.

1980-08-01

The sound velocities v L, v T 1 and v T 2 have been measured at 15 MHz on Tm 3+0.87Se and Tm 2.8+0.99Se between 300 K and 4.2 K and the elastic constants c ij have been derived. In intermediate valent Tm 2.8+0.99Se c 12 turned out to be negative. This sign is interpreted as being typical for intermediate valent compounds. Also for the first time experimental evidence is given for crystal field effects in Tm 3+0.87Se. Strong elastic nonlinearities are observed in intermediate valent Tm 2.8+0.99Se with uniaxial pressure.

Cryogenic Tm:YAP microchip laser

NASA Astrophysics Data System (ADS)

Hubka, Zbyněk.; Å ulc, Jan; Jelínková, Helena; Nejezchleb, Karel; Å koda, Václav

2016-04-01

The spectral characteristics of laser active media, and thus those of the laser output, are temperature dependent. Specifically, in almost every crystal host, cooling to low temperatures leads to better heat removal, a higher efficiency and output power, and a reduced lasing threshold. Tm-ion doped lasers have an emission wavelength around 2 μm and are important in medicine for soft tissue cutting and hemostasis, as well as in LIDAR or atmosphere sensing technology. This paper presents the performance-temperature dependency of a 4 at. % doped Tm:YAP microchip. During the experiment the Tm:YAP crystal was placed inside an evacuated liquid nitrogen cryostat on a cooling finger. As its temperature was varied from 80 K to 340 K, changes were observed in the absorption spectrum, ranging from 750 nm to 2000 nm and in the fluorescence spectrum from 1600 nm to 2050 nm. Fluorescence lifetime was seen to rise and fall with decreasing temperature. The laser was pumped by a 792 nm laser diode and at 80 K the maximum output peak power of the laser was 4.6 W with 23 % slope efficiency and 0.6 W threshold, compared to 2.4 W output peak power, 13 % slope efficiency and 3.3 W threshold when at 340 K. The laser emission wavelength changed from 1883 nm to 1993 nm for 80 K and 300 K, respectively.

Review of Tm and Ho Materials; Spectroscopy and Lasers

NASA Technical Reports Server (NTRS)

Walsh, Brian M.

2008-01-01

A review of Tm and Ho materials is presented, covering some fundamental aspects on the spectroscopy and laser dynamics in both single and co-doped systems. Following an introduction to 2- m lasers, applications and historical development, the physics of quasi-four level lasers, energy transfer and modeling are discussed in some detail. Recent developments in using Tm lasers to pump Ho lasers are discussed, and seen to offer some advantages over conventional Tm:Ho lasers. This article is not intended as a complete review, but as a primer for introducing concepts and a resource for further study.

Characterization of TM8, a MADS-box gene expressed in tomato flowers.

PubMed

Daminato, Margherita; Masiero, Simona; Resentini, Francesca; Lovisetto, Alessandro; Casadoro, Giorgio

2014-11-30

The identity of flower organs is specified by various MIKC MADS-box transcription factors which act in a combinatorial manner. TM8 is a MADS-box gene that was isolated from the floral meristem of a tomato mutant more than twenty years ago, but is still poorly known from a functional point of view in spite of being present in both Angiosperms and Gymnosperms, with some species harbouring more than one copy of the gene. This study reports a characterization of TM8 that was carried out in transgenic tomato plants with altered expression of the gene. Tomato plants over-expressing either TM8 or a chimeric repressor form of the gene (TM8:SRDX) were prepared. In the TM8 up-regulated plants it was possible to observe anomalous stamens with poorly viable pollen and altered expression of several floral identity genes, among them B-, C- and E-function ones, while no apparent morphological modifications were visible in the other whorls. Oblong ovaries and fruits, that were also parthenocarpic, were obtained in the plants expressing the TM8:SRDX repressor gene. Such ovaries showed modified expression of various carpel-related genes. No apparent modifications could be seen in the other flower whorls. The latter plants had also epinastic leaves and malformed flower abscission zones. By using yeast two hybrid assays it was possible to show that TM8 was able to interact in yeast with MACROCALIX. The impact of the ectopically altered TM8 expression on the reproductive structures suggests that this gene plays some role in the development of the tomato flower. MACROCALYX, a putative A-function MADS-box gene, was expressed in all the four whorls of fully developed flowers, and showed quantitative variations that were opposite to those of TM8 in the anomalous stamens and ovaries. Since the TM8 protein interacted in vitro only with the A-function MADS-box protein MACROCALYX, it seems that for the correct differentiation of the tomato reproductive structures possible interactions between

[Study of serum thrombomodulin(TM) levels in patients with hyper- or hypo- thyroidism].

PubMed

Soma, M; Maeda, Y; Matsuura, R; Sasaki, I; Kasakura, S; Saeki, Y; Ikekubo, K; Ishihara, T; Kurahachi, H; Sasaki, S; Tagami, T; Nakao, K

1997-01-01

We studies a relationship between the serum levels of thrombomodulin(TM) and the thyroid functions. Serum TM levels were measured in 48 patients with Graves' disease, 17 patients with primary hypothyroidism, 7 patients with subacute thyroiditis, 5 patients with painless thyroiditis and 2 patients with systematic Refetoff syndrome. These patients did not have malignant tumor, kidney failure, or blood vessel injury. Control sera were obtained from 42 healthy subjects. Serum levels of TM in patients with untreated Graves' disease were significantly higher(p < 0.001) compared with those in controls. Serum levels of TM in patients with hypothyroidism were not significantly changed as compared with those of controls. There were a positive correlation between the serum levels of TM and FT3 as well as FT4. Serial determinations of the serum levels of TM and thyroid function(FT3, FT4 and TH) in patients with Graves' disease during treatment showed that both the serum levels of TM and thyroid hormones (FT3 and FT4) lowered progressively during treatment. After normalization of serum FT3 and FT4, the serum TM levels returned to normal. However, the serum levels of TM in patients with destructive thyroiditis and Refetoff syndrome were normal in spite of high serum levels of thyroid hormones. These data suggest that an increase in serum levels of TM is not the direct result of thyroid hormones themselves but is the result of the prolonged hypermetabolic state induced by their peripheral activities. Thyroid hormones may stimulate the synthesis or metabolism of TM on the surface of vascular endothelial cells in the patients with Graves' disease.

The role of charge transfer in the oxidation state change of Ce atoms in the TM13-CeO2(111) systems (TM = Pd, Ag, Pt, Au): a DFT + U investigation.

PubMed

Tereshchuk, Polina; Freire, Rafael L H; Ungureanu, Crina G; Seminovski, Yohanna; Kiejna, Adam; Da Silva, Juarez L F

2015-05-28

Despite extensive studies of transition metal (TM) clusters supported on ceria (CeO2), fundamental issues such as the role of the TM atoms in the change in the oxidation state of Ce atoms are still not well understood. In this work, we report a theoretical investigation based on static and ab initio molecular dynamics density functional theory calculations of the interaction of 13-atom TM clusters (TM = Pd, Ag, Pt, Au) with the unreduced CeO2(111) surface represented by a large surface unit cell and employing Hubbard corrections for the strong on-site Coulomb correlation in the Ce f-electrons. We found that the TM13 clusters form pyramidal-like structures on CeO2(111) in the lowest energy configurations with the following stacking sequence, TM/TM4/TM8/CeO2(111), while TM13 adopts two-dimensional structures at high energy structures. TM13 induces a change in the oxidation state of few Ce atoms (3 of 16) located in the topmost Ce layer from Ce(IV) (itinerant Ce f-states) to Ce(III) (localized Ce f-states). There is a charge flow from the TM atoms to the CeO2(111) surface, which can be explained by the electronegativity difference between the TM (Pd, Ag, Pt, Au) and O atoms, however, the charge is not uniformly distributed on the topmost O layer due to the pressure induced by the TM13 clusters on the underlying O ions, which yields a decrease in the ionic charge of the O ions located below the cluster and an increase in the remaining O ions. Due to the charge flow mainly from the TM8-layer to the topmost O-layer, the charge cannot flow from the Ce(IV) atoms to the O atoms with the same magnitude as in the clean CeO2(111) surface. Consequently, the effective cationic charge decreases mainly for the Ce atoms that have a bond with the O atoms not located below the cluster, and hence, those Ce atoms change their oxidation state from IV to III. This increases the size of the Ce(III) compared with the Ce(IV) cations, which builds-in a strain within the topmost Ce layer, and

CCRS proposal for evaluating LANDSAT-4 MSS and TM data

NASA Technical Reports Server (NTRS)

Strome, W. M.; Cihlar, J.; Goodenough, D. G.; Guertin, F. E. (Principal Investigator); Guindon, B.; Murphy, J.; Butlin, J. M.; Duff, P.; Fitzgerald, A.; Grieve, G.

1984-01-01

The measurement of registration errors in LANDSAT MSS data is discussed as well as the development of a revised algorithm for the radiometric calibration of TM data and the production of a geocoded TM image.

TmDOTA -: A Sensitive Probe for MR Thermometry in Vivo

NASA Astrophysics Data System (ADS)

Zuo, Chun S.; Mahmood, Ashfaq; Sherry, A. Dean

2001-07-01

The lanthanide complex, thulium 1,4,7,10-tetraazacyclodo- decane-1,4,7,10-tetraacetic acid (TmDOTA-), has been investigated as an agent for MR thermometry in vivo. The chemical shifts of the TmDOTA- protons were highly sensitive to temperature at a clinically relevant field strength, yet insensitive to pH and the presence of Ca2+. Given the excellent stability of lanthanide-DOTA complexes and high thermal sensitivity, TmDOTA- is expected to be a good candidate for MR thermometry in vivo.

Listening and Legos[TM

ERIC Educational Resources Information Center

Morris, Pamela

2012-01-01

This simple exercise, performed in teams, gives students practice in listening to instructions, particularly when there are restrictions for the communication. The teams compete in a limited amount of time to build a Lego[TM] structure based on the instructions of one team member. Which team listens the best and is most successful?

Full Immersive Virtual Environment Cave[TM] in Chemistry Education

ERIC Educational Resources Information Center

Limniou, M.; Roberts, D.; Papadopoulos, N.

2008-01-01

By comparing two-dimensional (2D) chemical animations designed for computer's desktop with three-dimensional (3D) chemical animations designed for the full immersive virtual reality environment CAVE[TM] we studied how virtual reality environments could raise student's interest and motivation for learning. By using the 3ds max[TM], we can visualize…

Doors to Discovery[TM]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2007

2007-01-01

"Doors to Discovery"[TM] is an early childhood curriculum that uses thematic units to engage young children and support them as they build an understanding of their world. "Doors to Discovery"[TM] literacy activities are used to encourage children's development in a number of areas identified by research as the foundation for…

Analysis of intrinsic optical bistability in Tm-doped laser-related crystals

NASA Astrophysics Data System (ADS)

Noginov, M. A.; Vondrova, M.; Casimir, D.

2003-11-01

We predict and theoretically study intrinsic optical bistability (IOB) mediated by nonlinear energy transfer processes in rare-earth-doped laser-related crystals. In particular, we investigate Tm-Ho and Tm-Yb systems, in which avalanche pumping is overimposed by energy transfer up-conversion. We predict that IOB can be experimentally observed in (Tm,Yb):BaY2F8 crystals in a wide range of experimentally achievable parameters.

Origin of modulated phases and magnetic hysteresis in TmB 4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wierschem, Keola; Sunku, Sai Swaroop; Kong, Tai

In this study, we investigate the low-temperature magnetic phases in TmB 4, a metallic quantum magnet on the geometrically frustrated Shastry-Sutherland lattice, using coordinated experimental and theoretical studies. Our results provide an explanation for the appearance of the intriguing fractional plateau in TmB 4 and accompanying magnetic hysteresis. Together with observation of the bump in the half plateau, our results support the picture that the magnetization plateau structure in TmB 4 is strongly influenced by the zero-field modulated phases. We present a phenomenological model to explain the appearance of the modulated phases and a microscopic Hamiltonian that captures the completemore » magnetic behavior of TmB 4.« less

Origin of modulated phases and magnetic hysteresis in TmB 4

DOE PAGES

Wierschem, Keola; Sunku, Sai Swaroop; Kong, Tai; ...

2015-12-23

In this study, we investigate the low-temperature magnetic phases in TmB 4, a metallic quantum magnet on the geometrically frustrated Shastry-Sutherland lattice, using coordinated experimental and theoretical studies. Our results provide an explanation for the appearance of the intriguing fractional plateau in TmB 4 and accompanying magnetic hysteresis. Together with observation of the bump in the half plateau, our results support the picture that the magnetization plateau structure in TmB 4 is strongly influenced by the zero-field modulated phases. We present a phenomenological model to explain the appearance of the modulated phases and a microscopic Hamiltonian that captures the completemore » magnetic behavior of TmB 4.« less

Utilising eduroam[TM] Architecture in Building Wireless Community Networks

ERIC Educational Resources Information Center

Huhtanen, Karri; Vatiainen, Heikki; Keski-Kasari, Sami; Harju, Jarmo

2008-01-01

Purpose: eduroam[TM] has already been proved to be a scalable, secure and feasible way for universities and research institutions to connect their wireless networks into a WLAN roaming community, but the advantages of eduroam[TM] have not yet been fully discovered in the wireless community networks aimed at regular consumers. This aim of this…

TM-pass polarizer based on multilayer graphene polymer waveguide

NASA Astrophysics Data System (ADS)

Cai, Ke-su; Li, Yue-e.; Wei, Wen-jing; Mu, Xi-jiao; Ma, A.-ning; Wang, Zhong; Song, Dan-ming

2018-05-01

A TM-pass polarizer based on multilayer graphene polymer waveguide is proposed and theoretically analyzed. The mode properties, the extinction ratio, the insertion loss and the bandwidth are also discussed. The results show that a TM-pass polarizer, which only guides the TM mode, can be achieved by multilayer graphene polymer waveguide. With length of 150 μm, the proposed polarizer can achieve extinction ratio of 33 dB and insertion loss of 0.5 dB at optical wavelength of 1.55 μm. This device has an excellent performance, including large extinction ratio and low insertion loss within the spectral range from 1.45 μm to 1.6 μm.

Flashlamp-pumped Ho:Tm:Cr:LuAG laser

NASA Technical Reports Server (NTRS)

Jani, Mahendra G. (Inventor); Barnes, Norman P. (Inventor); Murray, Keith E. (Inventor); Kokta, Milan R. (Inventor)

1997-01-01

A room temperature solid-state laser is provided. A laser crystal is disposed in a laser cavity. The laser crystal has a LuAG host material doped with a concentration of about 0.35% Ho ions, about 5.57% Tm ions and at least about 1.01% Cr ions. A broadband energizing source such as a flashlamp is disposed transversely to the laser crystal to energize the Ho ions, Tm ions and Cr ions.

Discrimination of lithologic units using geobotanical and LANDSAT TM spectral data

NASA Technical Reports Server (NTRS)

Birnie, R. W.; Defeo, N. J.

1986-01-01

Thematic Mapper (TM) spectral data were correlated with lithologic units, geobotanical forest associations, and geomorphic site parameters in the Ridge and Valley Province of Pennsylvania. Both the TM and forest association data can be divided into four groups based on their lithology (sandstone or shale) and geomorphic aspect (north or south facing). In this clastic sedimentary terrane, geobotanical associations are useful indicators of lithology and these different geobotanical associations are detectable in LANDSAT TM data.

Data fusion of Landsat TM and IRS images in forest classification

Treesearch

Guangxing Wang; Markus Holopainen; Eero Lukkarinen

2000-01-01

Data fusion of Landsat TM images and Indian Remote Sensing satellite panchromatic image (IRS-1C PAN) was studied and compared to the use of TM or IRS image only. The aim was to combine the high spatial resolution of IRS-1C PAN to the high spectral resolution of Landsat TM images using a data fusion algorithm. The ground truth of the study was based on a sample of 1,020...

O*NET[TM] Career Exploration Tools. Version 3.0.

ERIC Educational Resources Information Center

Employment and Training Administration (DOL), Washington, DC.

Developed by the U.S. Department of Labor's Occupational Information Network (O*NET) team, the O*NET[TM] Career Exploration Tools (Version 3.0) consist of three main parts: (1) the Interest Profiler; (2) the Work Importance Locator; and (3) the O*NET[TM] Occupations Combined List. The Interest Profiler is a self-assessment career exploration tool…

Computations for the 16-foot transonic tunnel, NASA, Langley Research Center, revision 1

NASA Technical Reports Server (NTRS)

Mercer, Charles E.; Berrier, Bobby L.; Capone, Francis J.; Grayston, Alan M.; Sherman, C. D.

1987-01-01

The equations used by the 16 foot transonic tunnel in the data reduction programs are presented in eight modules. Each module consists of equations necessary to achieve a specific purpose. These modules are categorized in the following groups: tunnel parameters; jet exhaust measurements; skin friction drag; balance loads and model attitudes calculations; internal drag (or exit-flow distributions); pressure coefficients and integrated forces; thrust removal options; and turboprop options. This document is a companion document to NASA TM-83186, A User's Guide to the Langley 16 Foot Transonic Tunnel, August 1981.

Energy transfer upconversion in Er3+-Tm3+ codoped sodium silicate glass

NASA Astrophysics Data System (ADS)

Kumar, Vinod; Pandey, Anurag; Ntwaeaborwa, O. M.; Swart, H. C.

2018-04-01

Er3+/Tm3+ doped and codoped Na2O-SiO2-ZnO (NSZO) glasses were prepared by the conventional melt-quenching method. The amorphous nature of the prepared glasses was confirmed by the X-ray diffraction analysis. The optical absorption spectrum displayed several peaks, which correspond to Er3+ and Tm3+ dopant ions embedded into the NSZO glass. Both dopants experienced upconversion emission under 980 nm excitation. Efficient energy transfer from Er3+ to Tm3+ was observed in the co-doped samples to enhance the near infrared emission of the Tm3+ ions.

Cytoskeletal tropomyosin Tm5NM1 is required for normal excitation-contraction coupling in skeletal muscle.

PubMed

Vlahovich, Nicole; Kee, Anthony J; Van der Poel, Chris; Kettle, Emma; Hernandez-Deviez, Delia; Lucas, Christine; Lynch, Gordon S; Parton, Robert G; Gunning, Peter W; Hardeman, Edna C

2009-01-01

The functional diversity of the actin microfilaments relies in part on the actin binding protein tropomyosin (Tm). The muscle-specific Tms regulate actin-myosin interactions and hence contraction. However, there is less known about the roles of the numerous cytoskeletal isoforms. We have shown previously that a cytoskeletal Tm, Tm5NM1, defines a Z-line adjacent cytoskeleton in skeletal muscle. Recently, we identified a second cytoskeletal Tm in this region, Tm4. Here we show that Tm4 and Tm5NM1 define separate actin filaments; the former associated with the terminal sarcoplasmic reticulum (SR) and other tubulovesicular structures. In skeletal muscles of Tm5NM1 knockout (KO) mice, Tm4 localization was unchanged, demonstrating the specificity of the membrane association. Tm5NM1 KO muscles exhibit potentiation of T-system depolarization and decreased force rundown with repeated T-tubule depolarizations consistent with altered T-tubule function. These results indicate that a Tm5NM1-defined actin cytoskeleton is required for the normal excitation-contraction coupling in skeletal muscle.

Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation–Contraction Coupling in Skeletal Muscle

PubMed Central

Vlahovich, Nicole; Kee, Anthony J.; Van der Poel, Chris; Kettle, Emma; Hernandez-Deviez, Delia; Lucas, Christine; Lynch, Gordon S.; Parton, Robert G.; Gunning, Peter W.

2009-01-01

The functional diversity of the actin microfilaments relies in part on the actin binding protein tropomyosin (Tm). The muscle-specific Tms regulate actin-myosin interactions and hence contraction. However, there is less known about the roles of the numerous cytoskeletal isoforms. We have shown previously that a cytoskeletal Tm, Tm5NM1, defines a Z-line adjacent cytoskeleton in skeletal muscle. Recently, we identified a second cytoskeletal Tm in this region, Tm4. Here we show that Tm4 and Tm5NM1 define separate actin filaments; the former associated with the terminal sarcoplasmic reticulum (SR) and other tubulovesicular structures. In skeletal muscles of Tm5NM1 knockout (KO) mice, Tm4 localization was unchanged, demonstrating the specificity of the membrane association. Tm5NM1 KO muscles exhibit potentiation of T-system depolarization and decreased force rundown with repeated T-tubule depolarizations consistent with altered T-tubule function. These results indicate that a Tm5NM1-defined actin cytoskeleton is required for the normal excitation–contraction coupling in skeletal muscle. PMID:19005216

Modeling and experimental characterization of Blackglas(TM) polymer pyrolysis to ceramic and thermodynamic characterization of Blackglas(TM) ceramic

NASA Astrophysics Data System (ADS)

Wang, Feng

2000-10-01

The transformation of Blackglas(TM) polymer to ceramic is characterized by TGA-RGA/MS, Si29 and C13 NMR. Si29 NMR reveals a dependence between the postcure temperature and the microstructure of the resin. The postcure temperature that appears to give optimal mechanical and oxidative properties of Blackglas(TM) ceramic is around 150°C. The pyrolysis processing models, which are the Lumped Parameters Model (LPM), the Mechanistic Kinetic Model (MKM) and the Redistribution Reaction Model (RRM), are developed to provide an effective window of processing parameters rather than a costly, time-consuming trial and error approach. The Lumped Parameters Model (LPM) is developed to study the effects of various parameters such as temperature, curing conditions and heating rates on mass loss during the pyrolysis of resin and green composites. It can be used for the model-predictive control of the pyrolysis process; The Mechanistic Kinetic Model (MKM) is developed on the basis of known chemistry and architecture of the polysiloxane for the transformation of Blackglas(TM) polymer to ceramic and the evolution of gases. The effects of various heating protocols on the outgassing kinetics have been studied to develop an optimum protocol for a rapid pyrolysis process which gives a composite with desirable mechanical properties; The Redistribution Reaction Model (RRM) is proposed to describe how the microcompositions of silicon oxycarbide change with respect to temperature, and to the ratio O/Si in the polymer precursor. A Thermodynamic Additivity Model (TAM) is developed to estimate the heat capacity, standard heat of formation and entropy of Blackglas(TM) ceramic by means of the Neumann Kopp rule and the available thermodynamic data of the Si-C and Si-O systems. Thermal stability of this ceramic is investigated by constructing predominance diagrams, and it is shown that the internal degradation reactions, which account for a significant loss of strength, will proceed further in the

Walk Score(TM), Perceived Neighborhood Walkability, and walking in the US.

PubMed

Tuckel, Peter; Milczarski, William

2015-03-01

To investigate both the Walk Score(TM) and a self-reported measure of neighborhood walkability ("Perceived Neighborhood Walkability") as estimators of transport and recreational walking among Americans. The study is based upon a survey of a nationally-representative sample of 1224 American adults. The survey gauged walking for both transport and recreation and included a self-reported measure of neighborhood walkability and each respondent's Walk Score(TM). Binary logistic and linear regression analyses were performed on the data. The Walk Score(TM) is associated with walking for transport, but not recreational walking nor total walking. Perceived Neighborhood Walkability is associated with transport, recreational and total walking. Perceived Neighborhood Walkability captures the experiential nature of walking more than the Walk Score(TM).

Updating the NASA LEO Orbital Debris Environment Model with Recent Radar and Optical Observations and in Situ Measurements

NASA Technical Reports Server (NTRS)

Liou, J.-C.; Anz-Meador, P.; Matney, M. J.; Kessler, D. J.; Theall, J.; Johnson, N. L.

2000-01-01

The Low Earth Orbit (LEO, between 200 and 2000 km altitudes) debris environment has been constantly measured by NASA Johnson Space Center's Liquid Mirror Telescope (LMT) since 1996 (Africano et al. 1999, NASA JSC-28826) and by Haystack and Haystack Auxiliary radars at MIT Lincoln Laboratory since 1990 (Settecerri et al. 1999, NASA JSC-28744). Debris particles as small as 3 mm can be detected by the radars and as small as 3 cm can be measured by LMT. Objects about 10 cm in diameter and greater are tracked and catalogued by the US Space Surveillance Network. Much smaller (down to several micrometers) natural and debris particle populations can be estimated based on in situ measurements, such as Long Duration Exposure Facility, and based on analyses of returned surfaces, such as Hubble Space Telescope solar arrays, European Retrievable Carrier, and Space Shuttles. To increase our understanding of the current LEO debris environment, the Orbital Debris Program Office at NASA JSC has initiated an effort to improve and update the ORDEM96 model (Kessler et al. 1996, NASA TM-104825) utilizing the recently available data. This paper gives an overview of the new NASA orbital debris engineering model, ORDEM2000.

Thermo-selective Tm(x)Ti(1-x)O(2-x/2) nanoparticles: from Tm-doped anatase TiO2 to a rutile/pyrochlore Tm2Ti2O7 mixture. An experimental and theoretical study with a photocatalytic application.

PubMed

Navas, Javier; Sánchez-Coronilla, Antonio; Aguilar, Teresa; De los Santos, Desireé M; Hernández, Norge C; Alcántara, Rodrigo; Fernández-Lorenzo, Concha; Martín-Calleja, Joaquín

2014-11-07

This is an experimental and theoretical study of thulium doped TiO2 nanoparticles. From an experimental perspective, a method was used to synthesize thulium-doped TiO2 nanoparticles in which Tm(3+) replaces Ti(4+) in the lattice, which to our knowledge has neither been reported nor studied theoretically so far. Different proportions of anatase and rutile phases were obtained at different annealing temperatures, and XRD and Raman spectroscopy also revealed the presence of a pyrochlore phase (Tm2Ti2O7) at 1173 K. Thus, the structure of the Tm-doped nanoparticles was thermally-controlled. Furthermore, XPS showed the presence of Tm(3+) in the samples synthesized, which produces oxygen vacancies to maintain the local neutrality in the lattice. The presence of Tm(3+) in the samples led to changes in the UV-Vis absorption spectra, so they showed photoluminescence properties and new states in the band gap, which produce a new lower energy electronic transition than the main TiO2 one. Periodic DFT calculations were performed to understand the experimentally produced structures. The production of oxygen vacancies was analysed and the changes generated in the structure were fully detailed. The DOS and PDOS analyses confirmed the experimental results obtained using UV-Vis spectroscopy, and showed that the new electronic states in the band gap are due to interactions of the f state of Tm and the p state of O. Likewise, the charge study and the ELF analysis indicate that when Tm is introduced into the TiO2 structure, the Ti-O bond around the oxygen vacancy is strengthened. Finally, an example of a photocatalytic application was developed to show the high efficiency of the samples due to the heterojunction in the interfaces of the phases in the samples, which improved the charge separation and the good charge carrier mobility due to the presence of the pyrochlore phase, as was also shown theoretically.

Structural, Electronic and Elastic Properties of Heavy Fermion YbTM2 (TM= Ir and Pt) Laves Phase Compounds

NASA Astrophysics Data System (ADS)

Pawar, H.; Shugani, M.; Aynyas, M.; Sanyal, S. P.

2018-02-01

The structural, electronic and elastic properties of YbTM2 (TM = Ir and Pt) Laves phase intermetallic compounds which crystallize in cubic (MgCu2-type) structure, have been investigated using ab-initio full potential linearized augmented plane wave (FP-LAPW) method with LDA and LDA+U approximation. The calculated ground state properties such as lattice parameter (a0), bulk modulus (B) and its pressure derivative (B‧) are in good agreement with available experimental and theoretical data. The electronic properties are analyzed from band structures and density of states. Elastic constants are predicted first time for these compounds which obey the stability criteria for cubic system.

Acoustical phonon anomaly in the Raman spectra of intermediate valent TmSe 1-xTe x and Tm xSe

NASA Astrophysics Data System (ADS)

Treindl, A.; Wachter, P.

1980-12-01

In the Raman spectra of intermediate valent TmSe 1- xTe x the same anomaly within the acoustical phonon band at 60 cm -1 is found as in Tm xSe. The connection of this anomaly with the valence mixing is confirmed. In a one-dimensional model calculation it is shown that a renormalized LA dispersion curve can produce the observed anomalous peak in the phonon DOS. As an alternative interpretation the possibility of a low energy electronic excitation at 60 cm -1 is discussed.

Applying TM-polarization geoelectric exploration for study of low-contrast three-dimensional targets

NASA Astrophysics Data System (ADS)

Zlobinskiy, Arkadiy; Mogilatov, Vladimir; Shishmarev, Roman

2018-03-01

With using new field and theoretical data, it has been shown that applying the electromagnetic field of transverse magnetic (TM) polarization will give new opportunities for electrical prospecting by the method of transient processes. Only applying a pure field of the TM polarization permits poor three-dimensional objects (required metalliferous deposits) to be revealed in a host horizontally-layered medium. This position has good theoretical grounds. There is given the description of the transient electromagnetic method, that uses only the TM polarization field. The pure TM mode is excited by a special source, which is termed as a circular electric dipole (CED). The results of three-dimensional simulation (by the method of finite elements) are discussed for three real geological situations for which applying electromagnetic fields of transverse electric (TE) and transverse magnetic (TM) polarizations are compared. It has been shown that applying the TE mode gives no positive results, while applying the TM polarization field permits the problem to be tackled. Finally, the results of field works are offered, which showed inefficiency of application of the classical TEM method, whereas in contrast, applying the field of TM polarization makes it easy to identify the target.

Comparative analysis of different sensor data (Landsat-TM and MOMS) for earth observation and impact on future sensor development

NASA Technical Reports Server (NTRS)

Bodechtel, J.; Zilger, J.; Salomonson, V. V.

1986-01-01

The missions of the German Modular Optoelectronic Multispectral Scanner (MOMS) aboard two STS flights demonstrated the feasibility of a novel concept with regard to both technical and scientific objectives. On account of the successful missions, a cooperation was agreed between the German Federal Minister for Research nad Technology and NASA for comparing MOMS observations with the more familiar operational Landsat-TM data over selected test sites, as a means of obtaining some relative measure of performance. This paper summarizes the results obtained and presents the MOMS-02, a further experimental representative of the MOMS program aiming at the realization of an operational system for the mid-nineties.

Insights into GABA receptor signalling in TM3 Leydig cells.

PubMed

Doepner, Richard F G; Geigerseder, Christof; Frungieri, Monica B; Gonzalez-Calvar, Silvia I; Calandra, Ricardo S; Raemsch, Romi; Fohr, Karl; Kunz, Lars; Mayerhofer, Artur

2005-01-01

Gamma-aminobutyric acid (GABA) is an emerging signalling molecule in endocrine organs, since it is produced by endocrine cells and acts via GABA(A) receptors in a paracrine/autocrine fashion. Testicular Leydig cells are producers and targets for GABA. These cells express GABA(A) receptor subunits and in the murine Leydig cell line TM3 pharmacological activation leads to increased proliferation. The signalling pathway of GABA in these cells is not known in this study. We therefore attempted to elucidate details of GABA(A) signalling in TM3 and adult mouse Leydig cells using several experimental approaches. TM3 cells not only express GABA(A )receptor subunits, but also bind the GABA agonist [(3)H]muscimol with a binding affinity in the range reported for other endocrine cells (K(d) = 2.740 +/- 0.721 nM). However, they exhibit a low B(max) value of 28.08 fmol/mg protein. Typical GABA(A) receptor-associated events, including Cl(-) currents, changes in resting membrane potential, intracellular Ca(2+) or cAMP, were not measurable with the methods employed in TM3 cells, or, as studied in part, in primary mouse Leydig cells. GABA or GABA(A) agonist isoguvacine treatment resulted in increased or decreased levels of several mRNAs, including transcription factors (c-fos, hsf-1, egr-1) and cell cycle-associated genes (Cdk2, cyclin D1). In an attempt to verify the cDNA array results and because egr-1 was recently implied in Leydig cell development, we further studied this factor. RT-PCR and Western blotting confirmed a time-dependent regulation of egr-1 in TM3. In the postnatal testis egr-1 was seen in cytoplasmic and nuclear locations of developing Leydig cells, which bear GABA(A) receptors and correspond well to TM3 cells. Thus, GABA acts via an atypical novel signalling pathway in TM3 cells. Further details of this pathway remain to be elucidated. Copyright (c) 2005 S. Karger AG, Basel.

2-micron lasing in Tm:Lu2O3 ceramic: initial operation

NASA Astrophysics Data System (ADS)

Vetrovec, John; Filgas, David M.; Smith, Carey A.; Copeland, Drew A.; Litt, Amardeep S.; Briscoe, Eldridge; Schirmer, Ernestina

2018-03-01

We report on initial lasing of Tm:Lu2O3 ceramic laser with tunable output in the vicinity of 2 μm. Tm:Lu2O3 ceramic gain materials offer a much lower saturation fluence than the traditionally used Tm:YLF and Tm:YAG materials. The gain element is pumped by 796 nm diodes via a "2-for-1" crossrelaxation energy transfer mechanism, which enables high efficiency. The high thermal conductivity of the Lu2O3 host ( 18% higher than YAG) in combination with low quantum defect of 20% supports operation at high-average power. Konoshima's ceramic fabrication process overcomes the scalability limits of single crystal sesquioxides. Tm:Lu2O3 offers wide-bandwidth amplification of ultrashort pulses in a chirped-pulse amplification (CPA) system. A laser oscillator was continuously tuned over a 230 nm range from 1890 to 2120 nm while delivering up to 43W QCW output with up to 37% efficiency. This device is intended for initial testing and later seeding of a multi-pass edge-pumped disk amplifier now being developed by Aqwest which uses composite Tm:Lu2O3 disk gain elements.

Growth and optical characteristics of Tm-doped AlGaN layer grown by organometallic vapor phase epitaxy

NASA Astrophysics Data System (ADS)

Takatsu, J.; Fuji, R.; Tatebayashi, J.; Timmerman, D.; Lesage, A.; Gregorkiewicz, T.; Fujiwara, Y.

2018-04-01

We report on the growth and optical properties of Tm-doped AlGaN layers by organometallic vapor phase epitaxy (OMVPE). The morphological and optical properties of Tm-doped GaN (GaN:Tm) and Tm-doped AlGaN (AlGaN:Tm) were investigated by Nomarski differential interference contrast microscopy and photoluminescence (PL) characterization. Nomarski images reveal an increase of surface roughness upon doping Tm into both GaN and AlGaN layers. The PL characterization of GaN:Tm shows emission in the near-infrared range originating from intra-4f shell transitions of Tm3+ ions. In contrast, AlGaN:Tm also exhibits blue light emission from Tm3+ ions. In that case, the wider band gap of the AlGaN host allows energy transfer to higher states of the Tm3+ ions. With time-resolved PL measurements, we could distinguish three types of luminescent sites of Tm3+ in the AlGaN:Tm layer, having different decay times. Our results confirm that Tm ions can be doped into GaN and AlGaN by OMVPE, and show potential for the fabrication of novel high-color-purity blue light emitting diodes.

TM4SF5-mediated protein-protein networks and tumorigenic roles

PubMed Central

Lee, Jung Weon

2014-01-01

Transmembrane 4 L six family member 5 (TM4SF5), as a membrane glycoprotein with 4 transmembrane domains, is similar to the tetraspanins in terms of membrane topology and plays important roles in tumorigenesis and tumor metastasis. Especially, TM4SF5 appears to form a massive protein-protein complex consisting of diverse membrane proteins and/or receptors in addition to cytosolic signaling molecules to regulate their signaling activities during the pathological processes. TM4SF5 is shown to interact with integrins α2, α5, and β1, EGFR, IL6R, CD151, focal adhesion kinase (FAK), and c-Src. This review focuses on the significance of the interactions with regards to TM4SF5-positive tumorigenesis and metastasis. [BMB Reports 2014; 47(9): 483-487] PMID:25027595

Spectroscopy and microchip laser operation of Tm, Ho:KYW crystals with different Ho concentrations

NASA Astrophysics Data System (ADS)

Gusakova, N. V.; Kurilchik, S. V.; Yasukevich, A. S.; Kisel, V. E.; Dashkevich, V. I.; Orlovich, V. A.; Pavlyuk, A. A.; Vatnik, S. M.; Bagaev, S. N.; Kuleshov, N. V.

2018-02-01

The spectroscopic properties of Tm, Ho:KYW crystals with different Ho concentrations were investigated. The diode-pumped microchip laser operation of Tm (5 at.%), Ho (0.5 at.%):KYW and Tm (5 at.%), Ho (1 at.%):KYW was demonstrated. The highest, to our knowledge, output power of 480 mW with slope efficiency of 31% for CW Tm (5 at.%), Ho (0.5 at.%):KYW microchip laser was obtained.

TM digital image products for applications. [computer compatible tapes

NASA Technical Reports Server (NTRS)

Barker, J. L.; Gunther, F. J.; Abrams, R. B.; Ball, D.

1984-01-01

The image characteristics of digital data generated by LANDSAT 4 thematic mapper (TM) are discussed. Digital data from the TM resides in tape files at various stages of image processing. Within each image data file, the image lines are blocked by a factor of either 5 for a computer compatible tape CCT-BT, or 4 for a CCT-AT and CCT-PT; in each format, the image file has a different format. Nominal geometric corrections which provide proper geodetic relationships between different parts of the image are available only for the CCT-PT. It is concluded that detector 3 of band 5 on the TM does not respond; this channel of data needs replacement. The empty bin phenomenon in CCT-AT images results from integer truncations of mixed-mode arithmetric operations.

DC Stark addressing for quantum memory in Tm:YAG

NASA Astrophysics Data System (ADS)

Gerasimov, Konstantin; Minnegaliev, Mansur; Urmancheev, Ravil; Moiseev, Sergey

2017-10-01

We observed a linear DC Stark effect for 3H6 - 3H4 optical transition of Tm3+ ions in Y3Al5O12. We observed that application of electric field pulse suppresses the two-pulse photon echo signal. If we then apply a second electric pulse of opposite polarity the echo signal is restored again, which indicates the linear nature of the observed effect. The effect is present despite the D2 symmetry of the Tm3+ sites that prohibits a linear Stark effect. Experimental data analysis shows that the observed electric field influence can be attributed to defects that break the local crystal field symmetry near Tm3+ ions. Using this effect we demonstrate selective retrieval of light pulses in two-pulse photon echo.

Development of electrodes for the NASA iron/chromium

NASA Technical Reports Server (NTRS)

Swette, L.; Jalan, V.

1984-01-01

This program was directed primarily to the development of the negative (Cr3+/Cr2+) electrode for the NASA chromous/ferric Redox battery. The investigation of the effects of substrate processing and gold/lead catalyzation parameters on electrochemical performance were continued. In addition, the effects of reactant cross-mixing, acidity level, and temperature were examined for both Redox couples. Finally, the performance of optimized electrodes was tested in system hardware (1/3 square foot single cell). The major findings are discussed: (1) The recommended processing temperature for the carbon felt, as a substrate for the negative electrode, is 1650 to 1750 C, (2) The recommended gold catalyzation procedure is essentially the published NASA procedure (NASA TM-82724, Nov. 1981) based on deposition from aqueous methanol solution, with the imposition of a few controls such as temperature (25 C) and precatalyzation pH of the felt (7), (3) Experimental observations of the gold catalyzation process and subsequent electron microscopy indicate that the gold is deposited from the colloidal state, induced by contact of the solution with the carbon felt, (4) Electrodeposited lead appears to be present as a thin uniform layer over the entire surface of the carbon fibers, rather than an discrete particles, and (5) Cross-mixing of reactants (Fe-2+ in negative electrode solution or Cr-3+ in the positive electrode solution) did not appear to produce significant interference at either electrode.

Diverse Reactivity of ECp* (E = Al, Ga) toward Low-Coordinate Transition Metal Amides [TM(N(SiMe3)2)2] (TM = Fe, Co, Zn): Insertion, Cp* Transfer, and Orthometalation.

PubMed

Weßing, Jana; Göbel, Christoph; Weber, Birgit; Gemel, Christian; Fischer, Roland A

2017-03-20

The reactivity of the carbenoid group 13 metal ligands ECp* (E = Al, Ga) toward low valent transition metal complexes [TM(btsa) 2 ] (TM = Fe, Co, Zn; btsa = bis(trimethylsilyl)amide) was investigated, revealing entirely different reaction patterns for E = Al and Ga. Treatment of [Co(btsa) 2 ] with AlCp* yields [Cp*Co(μ-H)(Al(κ 2 -(CH 2 SiMe 2 )NSiMe 3 )(btsa))] (1) featuring an unusual heterometallic bicyclic structure that results from the insertion of AlCp* into the TM-N bond with concomitant ligand rearrangement including C-H activation at one amide ligand. For [Fe(btsa) 2 ], complete ligand exchange gives FeCp* 2 , irrespective of the employed stoichiometric ratio of the reactants. In contrast, treatment of [TM(btsa) 2 ] (TM = Fe, Co) with GaCp* forms the 1:1 and 1:2 adducts [(GaCp*)Co(btsa) 2 ] (2) and [(GaCp*) 2 Fe(btsa) 2 ] (3), respectively. The tendency of AlCp* to undergo Cp* transfer to the TM center appears to be dependent on the nature of the TM center: For [Zn(btsa) 2 ], no Cp* transfer is observed on reaction with AlCp*; instead, the insertion product [Zn(Al(η 2 -Cp*)(btsa)) 2 ] (4) is formed. In the reaction of [Co(btsa) 2 ] with the trivalent [Cp*AlH 2 ], transfer of the amide ligands without further ligand rearrangement is observed, leading to [Co(μ-H) 4 (Al(η 2 -Cp*)(btsa)) 2 ] (5).

Theoretical investigation of thermoelectric and elastic properties of intermetallic compounds ScTM (TM = Cu, Ag, Au and Pd)

NASA Astrophysics Data System (ADS)

Iqbal, R.; Bilal, M.; Jalali-Asadabadi, S.; Rahnamaye Aliabad, H. A.; Ahmad, Iftikhar

2018-01-01

In this paper, we explore the structural, electronic, thermoelectric and elastic properties of intermetallic compounds ScTM (TM = Cu, Ag, Au and Pd) using density functional theory. The produced results show high values of Seebeck coefficients and electrical conductivity for these materials. High power factor for these materials at room-temperature shows that these materials may be beneficial for low-temperature thermoelectric devices and alternative energy sources. Furthermore, elastic properties of these compounds are also calculated, which are used to evaluate their mechanical properties. The Cauchy’s pressure and B/G ratio figure out that these compounds are ductile in nature. The calculated results also predict that these compounds are stable against deforming force.

Preliminary Comparisons of the Information Content and Utility of TM Versus MSS Data

NASA Technical Reports Server (NTRS)

Markham, B. L.

1984-01-01

Comparisons were made between subscenes from the first TM scene acquired of the Washington, D.C. area and a MSS scene acquired approximately one year earlier. Three types of analyses were conducted to compare TM and MSS data: a water body analysis, a principal components analysis and a spectral clustering analysis. The water body analysis compared the capability of the TM to the MSS for detecting small uniform targets. Of the 59 ponds located on aerial photographs 34 (58%) were detected by the TM with six commission errors (15%) and 13 (22%) were detected by the MSS with three commission errors (19%). The smallest water body detected by the TM was 16 meters; the smallest detected by the MSS was 40 meters. For the principal components analysis, means and covariance matrices were calculated for each subscene, and principal components images generated and characterized. In the spectral clustering comparison each scene was independently clustered and the clusters were assigned to informational classes. The preliminary comparison indicated that TM data provides enhancements over MSS in terms of (1) small target detection and (2) data dimensionality (even with 4-band data). The extra dimension, partially resultant from TM band 1, appears useful for built-up/non-built-up area separation.

Detection of soil erosion within pinyon-juniper woodlands using Thematic Mapper (TM) data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Price, K.P.

1993-09-01

Multispectral measurements collected by Landsat Thematic Mapper (TM) were correlated with field measurements, direct soil loss estimates, and Universal Soil Loss Equation (USLE) estimates to determine the sensitivity of TM data to varying degrees of soil erosion in pinyon-juniper woodland in central Utah. TM data were also evaluated as a predictor of the USLE Crop Management C factor for pinyon-juniper woodlands. Correlation analysis showed that TM Band 4 (near infrared) accounted for 78% of the variability in percent trees (r=[minus] 0.88). In multiple regression, percent trees, total soil loss, and percent total nonliving cover together accounted for nearly 70% ofmore » the variability in TM Bands 2, 3, 4, and 5. TM spectral data were consistently better predictors of soil erosion factors than any combination of field factors. TM data were more sensitive to vegetation variations than the USLE C factor. USLE estimates showed low annual rates of erosion which varied little among the study sites. A number of hypotheses have been advanced to explain the apparent accelerated rate of pinyon-juniper spread in the western United States. These include removal of natural plant competition by livestock overgrazing, reduction of wildfires, climatic change, and reinvasion of sites cleared of trees by 19th century settlers.« less

Efficient 2-μm Tm:YAP Q-switched and CW lasers

NASA Astrophysics Data System (ADS)

Hays, A. D.; Cole, Brian; King, Vernon; Goldberg, Lew

2018-02-01

Highly efficient, diode pumped Tm:YAP lasers generating emission in the 1.85-1.94 μm range are demonstrated and characterized. Laser optical efficiencies of 51% and 45%, and electrical efficiencies of 31% and 25% are achieved under CW and Q-switched operation, respectively. Laser performance was characterized for maximum average powers up to 20W with various cavity configurations, all using an intra-cavity lens to compensate for thermal lensing in the Tm:YAP crystal. Q-switched lasers incorportating a Cr:ZnS saturable absorber (SA), resonant mechanical mirror scanner, or acousto-optic modulator were characterized. To enable higher average output powers, measurements of the thermal lens were conducted for the Tm:YAP crystal as a function of pump power and were compared to values predicted by a finiteelement- analysis (FEA) thermal-optical model of the Tm:YAP crystal. A resonator model is developed to incorporate this calculated thermal lens and its effect on laser performance. This paper will address approaches for improving the performance of Tm:YAP lasers, and means for achieving increased average output powers while maintaining high optical efficiency for both SA and mechanical Q-switching.

LANDSAT-D MSS/TM tuned orbital jitter analysis model LDS900

NASA Technical Reports Server (NTRS)

Pollak, T. E.

1981-01-01

The final LANDSAT-D orbital dynamic math model (LSD900), comprised of all test validated substructures, was used to evaluate the jitter response of the MSS/TM experiments. A dynamic forced response analysis was performed at both the MSS and TM locations on all structural modes considered (thru 200 Hz). The analysis determined the roll angular response of the MSS/TM experiments to improve excitation generated by component operation. Cross axis and cross experiment responses were also calculated. The excitations were analytically represented by seven and nine term Fourier series approximations, for the MSS and TM experiment respectively, which enabled linear harmonic solution techniques to be applied to response calculations. Single worst case jitter was estimated by variations of the eigenvalue spectrum of model LSD 900. The probability of any worst case mode occurrence was investigated.

Injection-seeded operation of a Q-switched Cr,Tm,Ho:YAG laser

NASA Technical Reports Server (NTRS)

Henderson, Sammy W.; Hale, Charley P.; Magee, James R.

1991-01-01

Single-frequency Tm,Ho:YAG lasers operating near 2 microns are attractive sources for several applications including eye-safe laser radar (lidar) and pumping of AgGaSe2 parametric oscillators for efficient generation of longer wavelengths. As part of a program to develop a coherent lidar system using Tm,Ho:YAG lasers, a diode laser-pumped tunable CW single-longitudinal-mode (SLM) Cr:Tm:Ho:YAG laser and a flashlamp-pumped single-transverse-mode Q-switched Cr,Tm,Ho:YAG laser were developed. The CW laser was used to injection-seed the flashlamp-pumped laser, resulting in SLM Q-switched output. Operational characteristics of the CW and Q-switched lasers and injection-seeding results are reported.

Graphing Calculators, the CBL2[TM] and TI-Interactive[TM] in High School Science.

ERIC Educational Resources Information Center

Molnar, Bill

This collection of activities is designed to show how TI-Interactive[TM] and Calculator-based Laboratories (CBL) can be used to explore topics in high school science. The activities address such topics as specific heat, Boyle's Law, Newton's Law of Cooling, and Antarctic Ozone Levels. Teaching notes and calculator instructions are included as are…

Preliminary Study of Information Extraction of LANDSAT TM Data for a Suburban/regional Test Site

NASA Technical Reports Server (NTRS)

Toll, D. L.

1985-01-01

A substantial amount of spectral information is available from TM (as compared to MSS) data for a 14.25 square km area between Beltsville and Laurel, Maryland. Large buildings and street patterns were resolved in the TM imagery. While there was added information content in TM data for discriminating surburban/regional land cover, characteristics of MSS can improve land cover discrimination over TM when conventional classification procedures are used on digital data. The improved qualitization of TM is likely valuable in situations where there are spectral similarities between classes. The spatial resolution in TM decreased land cover discrimination as a result of increased within class variability. For many general digital evaluations, inclusion of four bands representing the four spectral regions can provide much useful land cover discrimination. Inclusion of TM 6 indicates an improvement in spectral class discrimination. Of primary spectral importance is the discrimination between water, vegetative surfaces, and impervious surfaces due to differences in thermal properties. Results from the principle component transformed data clearly indicates additional information content in TM over MSS.

Postflight aerothermodynamic analysis of Pegasus(tm) using computational fluid dynamic techniques

NASA Technical Reports Server (NTRS)

Kuhn, Gary D.

1992-01-01

The objective was to validate the computational capability of the NASA Ames Navier-Stokes code, F3D, for flows at high Mach numbers using comparison flight test data from the Pegasus (tm) air launched, winged space booster. Comparisons were made with temperature and heat fluxes estimated from measurements on the wing surfaces and wing-fuselage fairings. Tests were conducted for solution convergence, sensitivity to grid density, and effects of distributing grid points to provide high density near temperature and heat flux sensors. The measured temperatures were from sensors embedded in the ablating thermal protection system. Surface heat fluxes were from plugs fabricated of highly insulative, nonablating material, and mounted level with the surface of the surrounding ablative material. As a preflight design tool, the F3D code produces accurate predictions of heat transfer and other aerodynamic properties, and it can provide detailed data for assessment of boundary layer separation, shock waves, and vortex formation. As a postflight analysis tool, the code provides a way to clarify and interpret the measured results.

High quality TmIG films with perpendicular magnetic anisotropy grown by sputtering

NASA Astrophysics Data System (ADS)

Wu, C. N.; Tseng, C. C.; Yeh, S. L.; Lin, K. Y.; Cheng, C. K.; Fanchiang, Y. T.; Hong, M.; Kwo, J.

Ferrimagnetic thulium iron garnet (TmIG) films grown on gadolinium gallium garnet substrates recently showed stress-induced perpendicular magnetic anisotropy (PMA), attractive for realization of quantum anomalous Hall effect (QAHE) of topological insulator (TI) films via the proximity effect. Moreover, current induced magnetization switching of Pt/TmIG has been demonstrated for the development of room temperature (RT) spintronic devices. In this work, high quality TmIG films (about 25nm) were grown by sputtering at RT followed by post-annealing. We showed that the film composition is tunable by varying the growth parameters. The XRD results showed excellent crystallinity of stoichiometric TmIG films with an out-of-plane lattice constant of 1.2322nm, a narrow film rocking curve of 0.017 degree, and a film roughness of 0.2 nm. The stoichiometric films exhibited PMA and the saturation magnetization at RT was 109 emu/cm3 (RT bulk value 110 emu/cm3) with a coercive field of 2.7 Oe. In contrast, TmIG films of Fe deficiency showed in-plane magnetic anisotropy. The high quality sputtered TmIG films will be applied to heterostructures with TIs or metals with strong spin-orbit coupling for novel spintronics.

Thermal and optical properties of Tm3+ doped tellurite glasses.

PubMed

Ozen, G; Demirata, B; Oveçoğlu, M L; Genç, A

2001-02-01

Ultraviolet, visible (UV/VIS) and differential thermal analysis (DTA) measurements were carried out in order to investigate the optical and thermal properties of various 0.5 mol.% Tm2O3 containing (1 - x)TeO2 + xLiCl glasses in molar ratio. The samples were prepared by fusing the mixture of their respective reagent grade powders in a platinum cricuble at 750 degrees C for 30 min. DTA curves taken in the 23-600 degrees C temperature range with a heating rate of 10 degrees C/min reveal a change in the value of the glass transition temperature, Tg, while melting was not observed for the glasses containing LiCl content less than 50 mol.%. These glasses were found to be moisture-resistant. However, the glasses with LiCl content higher than 50 mol.%, in which a melting peak was observed at Tc = 401 degrees C, were moisture-sensitive. Absorption measurements in the UV/VIS region of the glasses without Tm2O3 content show that the Urbach cutoff occurs at about 320 nm and, is relatively independent of the LiCl content. Six absorption bands were observed in the Tm2O3 doped glasses corresponding to the absorption of the 1G4, 3F2, 3F3 and 3F4, 3H5 and 3H4 levels from the 3H6 ground level of Tm3+ ions. The spectra also show that the integrated absorption cross-section of each band depends on the glass composition. Judd-Ofelt theory was used to determine the Judd-Ofelt parameters as well as the radiative transition probabilities for the metastable levels of Tm3+ ions in (0.3)LiCl + (0.7) TeO2: 0.01 Tm2O3 glass which is moisture-resistant.

Luminescent properties of Tm3-xLuxAl5O12:Ce single crystalline films

NASA Astrophysics Data System (ADS)

Zorenko, Yu.; Gorbenko, V.; Zorenko, T.; Suchocki, A.; Zhydachevskyy, Ya.; Fabisiak, K.; Paprocki, K.; Bilski, P.; Twardak, A.; Fedorov, A.

2017-07-01

The work devoted to the investigation of a new luminescent and scintillation material based on the single crystalline films (SCFs) of Tm3-xLuxAG:Ce garnet; x = 0-1.5, grown by LPE method from PbO based flux. The best scintillation properties are achieved for SCFs of Tm1.5Lu1.5Al5O12:Ce composition. We have found that direct Tm → Ce and backside Ce → Tm energy transfer processes are observed in Tm1.5Lu1.5Al5O12:Ce. Due to elimination of traps in the 300-450 °C range, the relatively fast scintillation decay is realized in highly doped Tm1.5Lu1.5Al5O12:Ce SCFs. For this reason, Tm doping can be considered as a suitable way for improvement of the scintillation efficiency in other Ce3+ doped garnet compounds.

Analysis of forest disturbance using TM and AVHRR data

NASA Technical Reports Server (NTRS)

Spanner, Michael A.; Hlavka, Christine A.; Pierce, Lars L.

1989-01-01

A methodology that will be used to determine the proportions of undisturbed, successional vegetation and recently disturbed land cover within coniferous forests using remotely sensed data from the advanced very high resolution radiometer (AVHRR) is presented. The method uses thematic mapper (TM) data to determine the proportions of the three stages of forest disturbance and regrowth for each AVHRR pixel in the sample areas, and is then applied to interpret all AVHRR imagery. Preliminary results indicate that there are predictable relationships between TM spectral response and the disturbance classes. Analysis of ellipse plots from a TM classification of the disturbed forested landscape indicates that the forest classes are separable in the red (0.63-0.69 micron) and near-infrared (0.76-0.90 micron) bands, providing evidence that the proportion of disturbance classes may be determined from AVHRR data.

PDB_TM: selection and membrane localization of transmembrane proteins in the protein data bank.

PubMed

Tusnády, Gábor E; Dosztányi, Zsuzsanna; Simon, István

2005-01-01

PDB_TM is a database for transmembrane proteins with known structures. It aims to collect all transmembrane proteins that are deposited in the protein structure database (PDB) and to determine their membrane-spanning regions. These assignments are based on the TMDET algorithm, which uses only structural information to locate the most likely position of the lipid bilayer and to distinguish between transmembrane and globular proteins. This algorithm was applied to all PDB entries and the results were collected in the PDB_TM database. By using TMDET algorithm, the PDB_TM database can be automatically updated every week, keeping it synchronized with the latest PDB updates. The PDB_TM database is available at http://www.enzim.hu/PDB_TM.

Localizome: a server for identifying transmembrane topologies and TM helices of eukaryotic proteins utilizing domain information

PubMed Central

Lee, Sunghoon; Lee, Byungwook; Jang, Insoo; Kim, Sangsoo; Bhak, Jong

2006-01-01

The Localizome server predicts the transmembrane (TM) helix number and TM topology of a user-supplied eukaryotic protein and presents the result as an intuitive graphic representation. It utilizes hmmpfam to detect the presence of Pfam domains and a prediction algorithm, Phobius, to predict the TM helices. The results are combined and checked against the TM topology rules stored in a protein domain database called LocaloDom. LocaloDom is a curated database that contains TM topologies and TM helix numbers of known protein domains. It was constructed from Pfam domains combined with Swiss-Prot annotations and Phobius predictions. The Localizome server corrects the combined results of the user sequence to conform to the rules stored in LocaloDom. Compared with other programs, this server showed the highest accuracy for TM topology prediction: for soluble proteins, the accuracy and coverage were 99 and 75%, respectively, while for TM protein domain regions, they were 96 and 68%, respectively. With a graphical representation of TM topology and TM helix positions with the domain units, the Localizome server is a highly accurate and comprehensive information source for subcellular localization for soluble proteins as well as membrane proteins. The Localizome server can be found at . PMID:16845118

The Speaking Section of the TOEFL iBT[TM] (SSTiBT): Test-Takers' Reported Strategic Behaviors. TOEFL iBT[TM] Research Report. RR-09-30

ERIC Educational Resources Information Center

Swain, Merrill; Huang, Li-Shih; Barkaoui, Khaled; Brooks, Lindsay; Lapkin, Sharon

2009-01-01

This study responds to the Test of English as a Foreign Language[TM] (TOEFL[R]) research agenda concerning the need to understand the processes and knowledge that test-takers utilize. Specifically, it investigates the strategic behaviors test-takers reported using when taking the Speaking section of the TOEFL iBT[TM] (SSTiBT). It also investigates…

TE/TM decomposition of electromagnetic sources

NASA Technical Reports Server (NTRS)

Lindell, Ismo V.

1988-01-01

Three methods are given by which bounded EM sources can be decomposed into two parts radiating transverse electric (TE) and transverse magnetic (TM) fields with respect to a given constant direction in space. The theory applies source equivalence and nonradiating source concepts, which lead to decomposition methods based on a recursive formula or two differential equations for the determination of the TE and TM components of the original source. Decompositions for a dipole in terms of point, line, and plane sources are studied in detail. The planar decomposition is seen to match to an earlier result given by Clemmow (1963). As an application of the point decomposition method, it is demonstrated that the general exact image expression for the Sommerfeld half-space problem, previously derived through heuristic reasoning, can be more straightforwardly obtained through the present decomposition method.

Does the use of Nintendo Wii SportsTM improve arm function? Trial of WiiTM in Stroke: a randomized controlled trial and economics analysis.

PubMed

Adie, Katja; Schofield, Christine; Berrow, Margie; Wingham, Jennifer; Humfryes, John; Pritchard, Colin; James, Martin; Allison, Rhoda

2017-02-01

The Trial of Wii™ in Stroke investigated the efficacy of using the Nintendo Wii Sports™ (Wii TM ) to improve affected arm function after stroke. Multicentre, pragmatic, parallel group, randomized controlled trial. Home-based rehabilitation. A total of 240 participants aged 24-90 years with arm weakness following a stroke within the previous six months. Participants were randomly assigned to exercise daily for six weeks using the Wii TM or arm exercises at home. Primary outcome was change in the affected arm function at six weeks follow-up using the Action Research Arm Test. Secondary outcomes included occupational performance, quality of life, arm function at six months and a cost effectiveness analysis. The study was completed by 209 participants (87.1%). There was no significant difference in the primary outcome of affected arm function at six weeks follow-up (mean difference -1.7, 95% CI -3.9 to 0.5, p = 0.12) and no significant difference in secondary outcomes, including occupational performance, quality of life or arm function at six months, between the two groups. No serious adverse events related to the study treatment were reported. The cost effectiveness analysis showed that the Wii TM was more expensive than arm exercises £1106 (SD 1656) vs. £730 (SD 829) (probability 0.866). The trial showed that the Wii TM was not superior to arm exercises in home-based rehabilitation for stroke survivors with arm weakness. The Wii TM was well tolerated but more expensive than arm exercises.

Yb3+ sensitized Tm3+ upconversion in tellurite lead oxide glass.

PubMed

Mohanty, Deepak Kumar; Rai, Vineet Kumar; Dwivedi, Y

2012-04-01

Triply ionized thulium/thulium--ytterbium doped/codoped TeO2-Pb3O4 (TPO) glasses have been fabricated by classical quenching method. The upconversion emission spectra in the Tm3+/Tm3+-Yb3+ doped/codoped glasses upon excitation with a diode laser lasing at ∼980 nm has been studied. Effect of the addition of the Yb3+ on the upconversion emission intensity in the visible and near infrared regions of the Tm3+ doped in TPO glass has been studied and the processes involved explored. Copyright © 2011 Elsevier B.V. All rights reserved.

Characterizing differences between MSCs and TM cells: Toward autologous stem cell therapies for the glaucomatous trabecular meshwork.

PubMed

Snider, Eric J; Vannatta, R Taylor; Schildmeyer, Lisa; Stamer, W Daniel; Ethier, C Ross

2018-03-01

Glaucoma, a leading cause of blindness, is characterized by an increase in intraocular pressure, which is largely determined by resistance to aqueous humour outflow through the trabecular meshwork (TM). In glaucoma, the cellularity of the TM is decreased, and, as a result, stem cell therapies for the TM represent a potential therapeutic option for restoring TM function and treating glaucoma patients. We here focus on adipose derived mesenchymal stem cells (MSCs) as a potential autologous cell source for TM regenerative medicine applications and describe characterization techniques at the messenger (reverse transcription-quantitative polymerase chain reaction), protein (western blotting, flow cytometry), and functional (contractility, phagocytosis) levels to distinguish MSCs from TM cells. We present a panel of 12 transcripts to allow: (a) suitable normalization of reverse transcription-quantitative polymerase chain reaction results across cell types and after exposure to potential differentiation stimuli; (b) distinguishing MSCs from TM cells; (c) distinguishing subtypes of TM cells; and (d) distinguishing TM cells from those in neighbouring tissue. At the protein level, dexamethasone induction of myocilin was a robust discriminating factor between MSCs and TM cells and was complemented by other protein markers. Finally, we show that contractility and phagocytosis differ between MSCs and TM cells. These methods are recommended for use in future differentiation studies to fully define if a functional TM-like phenotype is being achieved. Copyright © 2017 John Wiley & Sons, Ltd.

Preliminary Evaluation of TM for Soils Information

NASA Technical Reports Server (NTRS)

Thompson, D. R.; Henderson, K. E.; Houston, A. G.; Pitts, D. E.

1984-01-01

Thematic mapper data acquired over Mississippi County, Arkansas, were examined for utility in separating soil associations within generally level alluvium deposited by the Mississippi River. The 0.76 to 0.90 micron (Band 4) and the 1.55 to 1.75 micron (Band 5) were found to separate the different soil associations fairly well when compared to the USDA-SCS general soil map. The thermal channel also appeared to provide information at this level. A detailed soil survey was available at the field level along with ground observations of crop type, plant height, percent cover and growth stage. Soils within the fields ranged from uniform to soils that occur as patches of sand that stand out strongly against the intermingled areas of dark soil. Examination of the digital values of individual TM bands at the field level indicates that the influence of the soil is greater in TM than it was in MSS bands. The TM appears to provide greater detail of within field variability caused by soils than MSS and thus should provide improved information relating to crop and soil properties. However, this soil influence may cause crop identification classification procedures to have to account for the soil in their algorithms.

Cluster K Mycobacteriophages: Insights into the Evolutionary Origins of Mycobacteriophage TM4

PubMed Central

Pope, Welkin H.; Ferreira, Christina M.; Jacobs-Sera, Deborah; Benjamin, Robert C.; Davis, Ariangela J.; DeJong, Randall J.; Elgin, Sarah C. R.; Guilfoile, Forrest R.; Forsyth, Mark H.; Harris, Alexander D.; Harvey, Samuel E.; Hughes, Lee E.; Hynes, Peter M.; Jackson, Arrykka S.; Jalal, Marilyn D.; MacMurray, Elizabeth A.; Manley, Coreen M.; McDonough, Molly J.; Mosier, Jordan L.; Osterbann, Larissa J.; Rabinowitz, Hannah S.; Rhyan, Corwin N.; Russell, Daniel A.; Saha, Margaret S.; Shaffer, Christopher D.; Simon, Stephanie E.; Sims, Erika F.; Tovar, Isabel G.; Weisser, Emilie G.; Wertz, John T.; Weston-Hafer, Kathleen A.; Williamson, Kurt E.; Zhang, Bo; Cresawn, Steven G.; Jain, Paras; Piuri, Mariana; Jacobs, William R.; Hendrix, Roger W.; Hatfull, Graham F.

2011-01-01

Five newly isolated mycobacteriophages –Angelica, CrimD, Adephagia, Anaya, and Pixie – have similar genomic architectures to mycobacteriophage TM4, a previously characterized phage that is widely used in mycobacterial genetics. The nucleotide sequence similarities warrant grouping these into Cluster K, with subdivision into three subclusters: K1, K2, and K3. Although the overall genome architectures of these phages are similar, TM4 appears to have lost at least two segments of its genome, a central region containing the integration apparatus, and a segment at the right end. This suggests that TM4 is a recent derivative of a temperate parent, resolving a long-standing conundrum about its biology, in that it was reportedly recovered from a lysogenic strain of Mycobacterium avium, but it is not capable of forming lysogens in any mycobacterial host. Like TM4, all of the Cluster K phages infect both fast- and slow-growing mycobacteria, and all of them – with the exception of TM4 – form stable lysogens in both Mycobacterium smegmatis and Mycobacterium tuberculosis; immunity assays show that all five of these phages share the same immune specificity. TM4 infects these lysogens suggesting that it was either derived from a heteroimmune temperate parent or that it has acquired a virulent phenotype. We have also characterized a widely-used conditionally replicating derivative of TM4 and identified mutations conferring the temperature-sensitive phenotype. All of the Cluster K phages contain a series of well conserved 13 bp repeats associated with the translation initiation sites of a subset of the genes; approximately one half of these contain an additional sequence feature composed of imperfectly conserved 17 bp inverted repeats separated by a variable spacer. The K1 phages integrate into the host tmRNA and the Cluster K phages represent potential new tools for the genetics of M. tuberculosis and related species. PMID:22053209

Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle.

PubMed

He, Xuesong; McLean, Jeffrey S; Edlund, Anna; Yooseph, Shibu; Hall, Adam P; Liu, Su-Yang; Dorrestein, Pieter C; Esquenazi, Eduardo; Hunter, Ryan C; Cheng, Genhong; Nelson, Karen E; Lux, Renate; Shi, Wenyuan

2015-01-06

The candidate phylum TM7 is globally distributed and often associated with human inflammatory mucosal diseases. Despite its prevalence, the TM7 phylum remains recalcitrant to cultivation, making it one of the most enigmatic phyla known. In this study, we cultivated a TM7 phylotype (TM7x) from the human oral cavity. This extremely small coccus (200-300 nm) has a distinctive lifestyle not previously observed in human-associated microbes. It is an obligate epibiont of an Actinomyces odontolyticus strain (XH001) yet also has a parasitic phase, thereby killing its host. This first completed genome (705 kb) for a human-associated TM7 phylotype revealed a complete lack of amino acid biosynthetic capacity. Comparative genomics analyses with uncultivated environmental TM7 assemblies show remarkable conserved gene synteny and only minimal gene loss/gain that may have occurred as TM7x adapted to conditions within the human host. Transcriptomic and metabolomic profiles provided the first indications, to our knowledge, that there is signaling interaction between TM7x and XH001. Furthermore, the induction of TNF-α production in macrophages by XH001 was repressed in the presence of TM7x, suggesting its potential immune suppression ability. Overall, our data provide intriguing insights into the uncultivability, pathogenicity, and unique lifestyle of this previously uncharacterized oral TM7 phylotype.

Cultivation of a human-associated TM7 phylotype reveals a reduced genome and epibiotic parasitic lifestyle

PubMed Central

He, Xuesong; McLean, Jeffrey S.; Edlund, Anna; Yooseph, Shibu; Hall, Adam P.; Liu, Su-Yang; Dorrestein, Pieter C.; Esquenazi, Eduardo; Hunter, Ryan C.; Cheng, Genhong; Nelson, Karen E.; Lux, Renate; Shi, Wenyuan

2015-01-01

The candidate phylum TM7 is globally distributed and often associated with human inflammatory mucosal diseases. Despite its prevalence, the TM7 phylum remains recalcitrant to cultivation, making it one of the most enigmatic phyla known. In this study, we cultivated a TM7 phylotype (TM7x) from the human oral cavity. This extremely small coccus (200–300 nm) has a distinctive lifestyle not previously observed in human-associated microbes. It is an obligate epibiont of an Actinomyces odontolyticus strain (XH001) yet also has a parasitic phase, thereby killing its host. This first completed genome (705 kb) for a human-associated TM7 phylotype revealed a complete lack of amino acid biosynthetic capacity. Comparative genomics analyses with uncultivated environmental TM7 assemblies show remarkable conserved gene synteny and only minimal gene loss/gain that may have occurred as TM7x adapted to conditions within the human host. Transcriptomic and metabolomic profiles provided the first indications, to our knowledge, that there is signaling interaction between TM7x and XH001. Furthermore, the induction of TNF-α production in macrophages by XH001 was repressed in the presence of TM7x, suggesting its potential immune suppression ability. Overall, our data provide intriguing insights into the uncultivability, pathogenicity, and unique lifestyle of this previously uncharacterized oral TM7 phylotype. PMID:25535390

Systemic GLIPR1-ΔTM protein as a novel therapeutic approach for prostate cancer.

PubMed

Karantanos, Theodoros; Tanimoto, Ryuta; Edamura, Kohei; Hirayama, Takahiro; Yang, Guang; Golstov, Alexei A; Wang, Jianxiang; Kurosaka, Shinji; Park, Sanghee; Thompson, Timothy C

2014-04-15

GLIPR1 is a p53 target gene known to be downregulated in prostate cancer, and increased endogenous GLIPR1 expression has been associated with increased production of reactive oxygen species, increased apoptosis, decreased c-Myc protein levels and increased cell cycle arrest. Recently, we found that upregulation of GLIPR1 in prostate cancer cells increases mitotic catastrophe through interaction with heat shock cognate protein 70 (Hsc70) and downregulation of Aurora kinase A and TPX2. In this study, we evaluated the mechanisms of recombinant GLIPR1 protein (glioma pathogenesis-related protein 1-transmembrane domain deleted [GLIPR1-ΔTM]) uptake by prostate cancer cells and the efficacy of systemic GLIPR1-ΔTM administration in a prostate cancer xenograft mouse model. GLIPR1-ΔTM was selectively internalized by prostate cancer cells, leading to increased apoptosis through reactive oxygen species production and to decreased c-Myc protein levels. Interestingly, GLIPR1-ΔTM was internalized through clathrin-mediated endocytosis in association with Hsc70. Systemic administration of GLIPR1-ΔTM significantly inhibited VCaP xenograft growth. GLIPR1-ΔTM showed no evidence of toxicity following elimination from mouse models 8 hr after injection. Our results demonstrate that GLIPR1-ΔTM is selectively endocytosed by prostate cancer cells, leading to increased reactive oxygen species production and apoptosis, and that systemic GLIPR1-ΔTM significantly inhibits growth of VCaP xenografts without substantial toxicity. © 2013 UICC.

NASA's Earth Observations Program: Past, Present and Future

NASA Technical Reports Server (NTRS)

King, Michael D.

1999-01-01

A presentation will be given at the Annual National Awards and President's Invited Lecture. The event is sponsored by the Associated Scientific and Technical Societies, an organization which serves the interests of 40,000 scientists and engineers all over South Africa. A general presentation will be given on the topic of NASA's Earth Observation Program and will be supplemented with visualizations using the NASA/NOAA Earth Science Electronic theater. Included will be space observations with an eye on southern Africa, including Etosha National Park, Namibia, Okavanga Delta, Botswana, Victoria Falls, Zimbabwe, and Cape Town, the Highveld around Johannesburg, Blyde River Canyon, and the Lowveld of Kruger National Park in South Africa; also included will be some AVHRR imagery of fire occurrence during the dry season, mostly the Miombo woodland of Zambia, Angola, Malawi, and northern Mozambique, supplemented with SeaWiFS imagery for VI, aerosols, clouds, AVHRR fire time series, Landsat TM (and possibly ETM+, if available), and other global data sets. Would also like to include some Terra animations from SVS, including perhaps the launch sequence. The presentation would conclude with some of the ER-2 MAS imagery from Brazil that highlights the capability that we plan to bring to Africa in August 2000.

Effect and mode of action of the Texel muscling QTL (TM-QTL) on carcass traits in purebred Texel lambs.

PubMed

Macfarlane, J M; Lambe, N R; Matika, O; Johnson, P L; Wolf, B T; Haresign, W; Bishop, S C; Bünger, L

2014-07-01

TM-QTL is a quantitative trait locus (QTL) on ovine chromosome 18 (OAR18) known to affect loin muscling in Texel sheep. Previous work suggested that its mode of inheritance is consistent with paternal polar overdominance, but this has yet to be formally demonstrated. This study used purebred Texel sheep segregating for TM-QTL to confirm its presence in the chromosomal region in which it was first reported and to determine its pattern of inheritance. To do so, this study used the first available data from a Texel flock, which included homozygote TM-QTL carriers (TM/TM; n=34) in addition to homozygote non-carriers (+/+; n=40 and, heterozygote TM-QTL-carriers inheriting TM-QTL from their sire (TM/+; n=53) or their dam (+/TM; n=17). Phenotypes included a wide range of loin muscling, carcass composition and tissue distribution traits. The presence of a QTL affecting ultrasound muscle depth on OAR18 was confirmed with a paternal QTL effect ranging from +0.54 to +2.82 mm UMD (s.e. 0.37 to 0.57 mm) across the sires segregating for TM-QTL. Loin muscle width, depth and area, loin muscle volume and dissected M. longissimus lumborum weight were significantly greater for TM/+ than +/+ lambs (+2.9% to +7.9%; P<0.05). There was significant evidence that the effect of TM-QTL on the various loin muscling traits measured was paternally polar overdominant (P<0.05). In contrast, there was an additive effect of TM-QTL on both live weight at 20 weeks and carcass weight; TM/TM animals were significantly (P<0.05) heavier than +/+ (+11.1% and +7.3%, respectively) and +/TM animals (+11.9% and +11.7%, respectively), with TM/+ intermediate. Weights of the leg, saddle and shoulder region (corrected for carcass weight) were similar in the genotypic groups. There was a tendency for lambs inheriting TM-QTL from their sire to be less fat with slightly more muscle than non-carriers. For example, carcass muscle weight measured by live animal CT-scanning was 2.8% higher in TM/TM than +/+ lambs (P<0

Transmission electron microscopy study of the MgS–Tm{sub 2}S{sub 3} system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Varadé-López, R., E-mail: rebeca.varade@ucm.es; Ávila-Brande, D., E-mail: davilabr@ucm.es; Urones-Garrote, E., E-mail: esteban.urones@pdi.ucm.es

2015-09-15

This work presents the structural–microstructural characterization of the NaCl-derivative MgS–Tm{sub 2}S{sub 3} system, which can be formulated by the expression Mg{sub (1−x)}Tm{sub (2/3)x}□{sub (1/3)x}S (□→cation vacancy). Transmission electron microscopy observations show the transition between NaCl-type and spinel-type structures when 0 ≤x≤ 0.75. The increase of Tm content in the solid solution provokes the increase of the spinel-type phase proportion, which intergrows with the NaCl-type crystals. When x≥0.75, some phases derived from NaCl-type structure through the chemical twinning at the unit cell level crystallographic operation are observed, such as CT-MgTm{sub 2}S{sub 4} and CT-MgTm{sub 4}S{sub 7}. The existence and nature ofmore » the extended defects observed along the c direction of these structures are characterized by means of Scanning-Transmission electron microscopy high-angle dark field imaging, which allows observing the presence of quasi ordered crystals with new possible complex stoichiometries at atomic resolution. - Graphical abstract: HAADF-STEM image of a disordered CT-MgYb{sub 2}S{sub 4} crystal. The disordered twin-slab sequences are marked by arrows. - Highlights: • Structural evolution of the Mg{sub (1−x)}Tm{sub (2/3)x}□{sub (1/3)x}S system was characterized by means of TEM. • The increase in Tm content provokes the transition from NaCl to spinel-type structure up to x=0.75. • Chemical twinned phases CT-MgTm{sub 2}S{sub 4} and CT-MgTm{sub 4}S{sub 7} are observed at high Tm contents. • Extended defects in CT-crystals are characterized with atomic resolution STEM-HAADF images.« less

Magnetism, structures and stabilities of cluster assembled TM@Si nanotubes (TM = Cr, Mn and Fe): a density functional study.

PubMed

Dhaka, Kapil; Bandyopadhyay, Debashis

2016-08-02

The present study reports transition metal (TM = Cr, Mn and Fe) doped silicon nanotubes with tunable band structures and magnetic properties by careful selection of cluster assemblies as building blocks using the first-principles density functional theory. We found that the transition metal doping and in addition, the hydrogen termination process can stabilize the pure silicon nanoclusters or cluster assemblies and then it could be extended as magnetic nanotubes with finite magnetic moments. Study of the band structures and density of states (DOS) of different empty and TM doped nanotubes (Type 1 to Type 4) show that these nanotubes are useful as metals, semiconductors, semi-metals and half-metals. These designer magnetic materials could be useful in spintronics and magnetic devices of nanoscale order.

Seroepidemiology of TmPV1 infection in captive and wild Florida manatees (Trichechus manatus latirostris)

USGS Publications Warehouse

Dona, Maria Gabriella; Rehtanz, Manuela; Adimey, Nicole M.; Bossart, Gregory D.; Jenson, Alfred B.; Bonde, Robert K.; Ghim, Shin-je

2011-01-01

In 1997, cutaneous papillomatosis caused by Florida manatee (Trichechus manatus latirostris [Tm]) papillomavirus 1 (TmPV1) was detected in seven captive manatees at the Homosassa Springs Wildlife State Park, Florida, USA, and, subsequently, in two wild manatees from the adjacent Homosassa River. Since then, papillomatosis has been reported in captive manatees housed in other locations, but not in wild animals. To determine TmPV1 antibody prevalence in captive and wild manatees sampled at various locations throughout Florida coastal regions, virus-like particles, composed of the L1 capsid protein of TmPV1, were generated with a baculovirus expression system and used to measure anti-TmPV1 antibodies in an enzyme-linked immunosorbent assay. Serologic analysis of 156 manatees revealed a TmPV1 antibody prevalence of 26.3%, with no significant difference between captive (n=39) and wild (n=117) manatees (28.2% and 25.6%, respectively). No antibody-positive wild animal showed PV-induced cutaneous lesions, whereas papillomatosis was observed in 72.7% of antibody-positive captive manatees. Our data indicate that Florida manatees living in the wild are naturally infected by TmPV1 but rarely show TmPV1-induced papillomatosis. Hence, it appears that the wild population would not be harmed in a case of contact with captive animals without visible lesions and productive infections, which could be thus released into the wild.

Seroepidemiology of TmPV1 infection in captive and wild Florida manatees (Trichechus manatus latirostris).

PubMed

Donà, Maria Gabriella; Rehtanz, Manuela; Adimey, Nicole M; Bossart, Gregory D; Jenson, Alfred B; Bonde, Robert K; Ghim, Shin-je

2011-07-01

In 1997, cutaneous papillomatosis caused by Florida manatee (Trichechus manatus latirostris [Tm]) papillomavirus 1 (TmPV1) was detected in seven captive manatees at the Homosassa Springs Wildlife State Park, Florida, USA, and, subsequently, in two wild manatees from the adjacent Homosassa River. Since then, papillomatosis has been reported in captive manatees housed in other locations, but not in wild animals. To determine TmPV1 antibody prevalence in captive and wild manatees sampled at various locations throughout Florida coastal regions, virus-like particles, composed of the L1 capsid protein of TmPV1, were generated with a baculovirus expression system and used to measure anti-TmPV1 antibodies in an enzyme-linked immunosorbent assay. Serologic analysis of 156 manatees revealed a TmPV1 antibody prevalence of 26.3%, with no significant difference between captive (n=39) and wild (n=117) manatees (28.2% and 25.6%, respectively). No antibody-positive wild animal showed PV-induced cutaneous lesions, whereas papillomatosis was observed in 72.7% of antibody-positive captive manatees. Our data indicate that Florida manatees living in the wild are naturally infected by TmPV1 but rarely show TmPV1-induced papillomatosis. Hence, it appears that the wild population would not be harmed in a case of contact with captive animals without visible lesions and productive infections, which could be thus released into the wild.

Tm:GGAG crystal for 2μm tunable diode-pumped laser

NASA Astrophysics Data System (ADS)

Šulc, Jan; Boháček, Pavel; Němec, Michal; Fibrich, Martin; Jelínková, Helena; Trunda, Bohumil; Havlák, Lubomír.; Jurek, Karel; Nikl, Martin

2016-04-01

The spectroscopy properties and wavelength tunability of diode pumped laser based on Tm-doped mixed gadolinium-gallium-aluminium garnet Gd3(GaxAl1-x)5O12 (Tm:GGAG) single crystal were investigated for the first time. The crystal was grown by Czochralski method in a slightly oxidative atmosphere using an iridium crucible. The tested Tm:GGAG sample was cut from the grown crystal boule perpendicularly to growth direction (c-axis). The composition of sample was determined using electron microprobe X-ray elemental analysis. For spectroscopy and laser experiments 3.5mm thick plane-parallel face-polished plate (without AR coatings) with composition Gd2.76Tm0.0736Ga2.67Al2.50O12 (2.67 at.% Tm/Gd) was used. A fiber (core diameter 400 μm, NA= 0.22) coupled laser diode (emission wavelength 786 nm) was used for longitudinal Tm:GGAG pumping. The laser diode was operating in the pulsed regime (10 ms pulse length, 10 Hz repetition rate, maximum power amplitude 18 W). The 145mm long semi-hemispherical laser resonator consisted of a flat pumping mirror (HR @ 1.8- 2.10 μm, HT @ 0.78 μm) and curved (r = 150mm) output coupler with a reflectivity of » 97% @ 1.8- 2.10 µm. The maximum laser output power amplitude 1.14W was obtained at wavelength 2003nm for absorbed pump power amplitude 4.12W. The laser slope efficiency was 37% in respect to absorbed pumping power. Wavelength tuning was accomplished by using 2mm thick MgF2 birefringent filter placed inside the laser resonator at the Brewster angle. The laser was continuously tunable over 180nm in a spectral region from 1856nm to 2036 nm.

Ligand field splittings in core level transitions for transition metal (TM) oxides: Tanabe-Sugano diagrams and (TM) dangling bonds in vacated O-atom defects

NASA Astrophysics Data System (ADS)

Lucovsky, Gerry; Wu, Kun; Pappas, Brian; Whitten, Jerry

2013-04-01

Defect states in the forbidden band-gap below the conduction band edge are active as electron traps in nano-grain high-) transition metal (TM) oxides with thickness >0.3 nm, e.g., ZrO2 and HfO2. These oxides have received considerable attention as gate-dielectrics in complementary metal oxide semiconductor (CMOS) devices, and more recently are emerging as candidates for charge storage and memory devices. To provide a theoretical basis for device functionality, ab-initio many-electron theory is combined with X-ray absorption spectroscopy (XAS) to study O K edge and TM core level transitions. These studies identify ligand field splittings (ΔLF) for defect state features,. When compared with those obtained from O-atom and TM-atom core spectroscopic transitions, this provides direct information about defect state sun-nm bonding arrangements. comparisons are made for (i) elemental TiO2 and Ti2O3 with different formal ionic charges, Ti4+ and Ti3+ and for (ii) Magneli Phase alloys, TinO2n-1, n is an integer 9>=n>3, and (TiO2)x(HfO2)1-x alloys. The alloys display multi-valent behavior from (i) different ionic-charge states, (ii} local bond-strain, and (iii) metallic hopping transport. The intrinsic bonding defects in TM oxides are identified as pairs of singly occupied dangling bonds. For 6-fold coordinated Ti-oxides defect excited states in 2nd derivative O K pre-edge spectra are essentially the same as single Ti-atom d2 transitions in Tanabe-Sugano (T-S) diagrams. O-vacated site defects in 8-fold coordinated ZrO2 and HfO2 are described by d8 T-S diagrams. T-S defect state ordering and splittings are functions of the coordination and symmetry of vacated site bordering TM atoms. ΔLF values from the analysis of T-S diagrams indicate medium range order (MRO) extending to 3rd and 4th nearest-neighbor (NN) TM-atoms. Values are different for 6-fold Ti, and 8-fold ZrO2 and HfO2, and scale inversely with differences in respective formal ionic radii. O-vacated site bonding

Tetraspan TM4SF5-dependent direct activation of FAK and metastatic potential of hepatocarcinoma cells

PubMed Central

Jung, Oisun; Choi, Suyong; Jang, Sun-Bok; Lee, Sin-Ae; Lim, Ssang-Taek; Choi, Yoon-Ju; Kim, Hye-Jin; Kim, Do-Hee; Kwak, Tae Kyoung; Kim, Hyeonjung; Kang, Minkyung; Lee, Mi-Sook; Park, Sook Young; Ryu, Jihye; Jeong, Doyoung; Cheong, Hae-Kap; Kim, Hyun Jeong; Park, Ki Hun; Lee, Bong-Jin; Schlaepfer, David D.; Lee, Jung Weon

2012-01-01

Summary Transmembrane 4 L six family member 5 (TM4SF5) plays an important role in cell migration, and focal adhesion kinase (FAK) activity is essential for homeostatic and pathological migration of adherent cells. However, it is unclear how TM4SF5 signaling mediates the activation of cellular migration machinery, and how FAK is activated during cell adhesion. Here, we showed that direct and adhesion-dependent binding of TM4SF5 to FAK causes a structural alteration that may release the inhibitory intramolecular interaction in FAK. In turn, this may activate FAK at the cell's leading edge, to promote migration/invasion and in vivo metastasis. TM4SF5-mediated FAK activation occurred during integrin-mediated cell adhesion. TM4SF5 was localized at the leading edge of the cells, together with FAK and actin-organizing molecules, indicating a signaling link between TM4SF5/FAK and actin reorganization machinery. Impaired interactions between TM4SF5 and FAK resulted in an attenuated FAK phosphorylation (the signaling link to actin organization machinery) and the metastatic potential. Our findings demonstrate that TM4SF5 directly binds to and activates FAK in an adhesion-dependent manner, to regulate cell migration and invasion, suggesting that TM4SF5 is a promising target in the treatment of metastatic cancer. PMID:23077174

Energy transfer in Tm,Ho:KYW crystal and diode-pumped microchip laser operation.

PubMed

Kurilchik, Sergey; Gusakova, Natali; Demesh, Maxim; Yasukevich, Anatol; Kisel, Viktor; Pavlyuk, Anatoly; Kuleshov, Nikolai

2016-03-21

An investigation of Tm-Ho energy transfer in Tm(5at.%),Ho(0.4at.%):KYW single crystal by two independent techiques was performed. Based on fluorescence dynamics measurements, energy transfer parameters P₇₁ and P₂₈ for direct (Tm→Ho) and back (Ho→Tm) transfers, respectively, as well as equilibrium constant Θ were evaluated. The obtained results were supported by calculation of microscopic interaction parameters according to the Förster-Dexter theory for a dipole-dipole interaction. Diode-pumped continuous-wave operation of Tm,Ho:KYW microchip laser was demonstrated, for the first time to our knowledge. Maximum output power of 77 mW at 2070 nm was achieved at the fundamental TEM₀₀ mode.

Defying Gravity Using Jenga[TM] Blocks

ERIC Educational Resources Information Center

Tan, Yin-Soo; Yap, Kueh-Chin

2007-01-01

This paper describes how Jenga[TM] blocks can be used to demonstrate the physics of an overhanging tower that appears to defy gravity. We also propose ideas for how this demonstration can be adapted for the A-level physics curriculum. (Contains 8 figures and 1 table.)

Draft Genome Sequence of the Lignocellulose Decomposer Thermobifida fusca Strain TM51.

PubMed

Tóth, Akos; Barna, Terézia; Nagy, István; Horváth, Balázs; Nagy, István; Táncsics, András; Kriszt, Balázs; Baka, Erzsébet; Fekete, Csaba; Kukolya, József

2013-07-11

Here, we present the complete genome sequence of Thermobifida fusca strain TM51, which was isolated from the hot upper layer of a compost pile in Hungary. T. fusca TM51 is a thermotolerant, aerobic actinomycete with outstanding lignocellulose-decomposing activity.

Impact of Maple(TM) on the design, instruction and performance in an undergraduate physics mathematical methods course

NASA Astrophysics Data System (ADS)

Runge, Alan Paul

1997-10-01

A traditional undergraduate physics course on mathematical methods has been redesigned to incorporate the use of Maplesp{sc {TM}}, a computer algebra program, during all aspects of the course. Topics covered were: complex number theory; series approximations; matrix theory; partial differentiation; vector algebra; and vector calculus. Five undergraduate students were enrolled, from sophomore to senior in academic class standing. A qualitative case study methodology was used to describe the changes in the course design resulting from the incorporation of Maplesp{sc {TM}} and their impact on the instruction of the course, and to determine the effects on the students' learning and development of problem solving skills in physics using Maplesp{sc {TM}} as a problem solving tool. The impact of using Maplesp{sc {TM}} on the number and types of interactions is presented. The entire semester long course was included in this study. Each class session is described in detail. Examples of the Maplesp{sc {TM}} materials used are given. The use of the Maplesp{sc {TM}} program was allowed on all homework and exams with each student having their own computer during class. Constraints were made so that the assessment emphasis remained on the mathematics and the conceptual understanding of the problem solving methods. All of the students demonstrated some level of proficiency in using Maplesp{TM} to solve the assigned problems. Strategies for effectively using Maplesp{TM} were presented and were individualized by the students. The students reported positive and negative impacts of using Maplesp{sc {TM}}. All of the students satisfactorily completed the course requirements, receiving final course grades from B to A+. All of them continued to voluntarily use Maplesp{sc {TM}} during the following semester. Instructional methods used included various lecture techniques without Maplesp{sc {TM}} assistance, lectures and demonstrations using only Maplesp{sc {TM}}, and student tasks

Scintillation properties of Tm-doped Lu 3Al 5O 12 single crystals

NASA Astrophysics Data System (ADS)

Sugiyama, Makoto; Fujimoto, Yutaka; Yanagida, Takayuki; Totsuka, Daisuke; Yokota, Yuui; Yoshikawa, Akira

2011-12-01

Using the micro-pulling-down (μ-PD) method, Tm-doped Lu 3Al 5O 12 (Tm:LuAG) single crystals were grown to examine their scintillation properties. In transmittance spectra, they exhibited about 80% transparency in the wavelengths longer than 320 nm and five absorption lines due to Tm 3+ 4f-4f transitions were observed. 241Am α-ray excited radioluminescence spectra were measured and intense 4f-4f emission peaks were observed with the host emission. When excited by 137Cs γ-Ray to obtain pulse height spectra, Tm 1% doped LuAG showed the highest light yield coupled with a photomultiplier (PMT) or a silicon avalanche photodiode (Si-APD). The light yield was estimated to be 5800 and 7300 photons/MeV for PMT and Si-APD, respectively. Decay time profiles consist of two exponential components and the fast and slow components are considered to be attributed to the host and the combination of the host and Tm 3+ 4f-4f emission, respectively.

Lyme Disease and YouTube TM: A Cross-Sectional Study of Video Contents.

PubMed

Basch, Corey H; Mullican, Lindsay A; Boone, Kwanza D; Yin, Jingjing; Berdnik, Alyssa; Eremeeva, Marina E; Fung, Isaac Chun-Hai

2017-08-01

Lyme disease is the most common tick-borne disease. People seek health information on Lyme disease from YouTube TM videos. In this study, we investigated if the contents of Lyme disease-related YouTube TM videos varied by their sources. Most viewed English YouTube TM videos (n = 100) were identified and manually coded for contents and sources. Within the sample, 40 videos were consumer-generated, 31 were internet-based news, 16 were professional, and 13 were TV news. Compared with consumer-generated videos, TV news videos were more likely to mention celebrities (odds ratio [OR], 10.57; 95% confidence interval [CI], 2.13-52.58), prevention of Lyme disease through wearing protective clothing (OR, 5.63; 95% CI, 1.23-25.76), and spraying insecticides (OR, 7.71; 95% CI, 1.52-39.05). A majority of the most popular Lyme disease-related YouTube TM videos were not created by public health professionals. Responsible reporting and creative video-making facilitate Lyme disease education. Partnership with YouTube TM celebrities to co-develop educational videos may be a future direction.

Landsat TM memory effect characterization and correction

USGS Publications Warehouse

Helder, D.; Boncyk, W.; Morfitt, R.

1997-01-01

Before radiometric calibration of Landsat Thematic Mapper (TM) data can be done accurately, it is necessary to minimize the effects of artifacts present in the data that originate in the instrument's signal processing path. These artifacts have been observed in downlinked image data since shortly after launch of Landsat 4 and 5. However, no comprehensive work has been done to characterize all the artifacts and develop methods for their correction. In this paper, the most problematic artifact is discussed: memory effect (ME). Characterization of this artifact is presented, including the parameters necessary for its correction. In addition, a correction algorithm is described that removes the artifact from TM imagery. It will be shown that this artifact causes significant radiometry errors, but the effect can be removed in a straightforward manner.

152 W average power Tm-doped fiber CPA system.

PubMed

Stutzki, Fabian; Gaida, Christian; Gebhardt, Martin; Jansen, Florian; Wienke, Andreas; Zeitner, Uwe; Fuchs, Frank; Jauregui, Cesar; Wandt, Dieter; Kracht, Dietmar; Limpert, Jens; Tünnermann, Andreas

2014-08-15

A high-power thulium (Tm)-doped fiber chirped-pulse amplification system emitting a record compressed average output power of 152 W and 4 MW peak power is demonstrated. This result is enabled by utilizing Tm-doped photonic crystal fibers with mode-field diameters of 35 μm, which mitigate detrimental nonlinearities, exhibit slope efficiencies of more than 50%, and allow for reaching a pump-power-limited average output power of 241 W. The high-compression efficiency has been achieved by using multilayer dielectric gratings with diffraction efficiencies higher than 98%.

Draft Genome Sequence of the Lignocellulose Decomposer Thermobifida fusca Strain TM51

PubMed Central

Tóth, Ákos; Barna, Terézia; Nagy, István; Horváth, Balázs; Nagy, István; Táncsics, András; Kriszt, Balázs; Baka, Erzsébet; Fekete, Csaba

2013-01-01

Here, we present the complete genome sequence of Thermobifida fusca strain TM51, which was isolated from the hot upper layer of a compost pile in Hungary. T. fusca TM51 is a thermotolerant, aerobic actinomycete with outstanding lignocellulose-decomposing activity. PMID:23846276

Fiber-optic thermometry using thermal radiation from Tm end doped SiO{sub 2} fiber sensor

DOE Office of Scientific and Technical Information (OSTI.GOV)

Morita, Kentaro; Katsumata, Toru; Komuro, Shuji

2014-04-15

Fiber-optic thermometry based on temperature dependence of thermal radiation from Tm{sup 3+} ions was studied using Tm end doped SiO{sub 2} fiber sensor. Visible light radiation peaks due to f-f transition of Tm{sup 3+} ion were clearly observed at λ = 690 and 790 nm from Tm end doped SiO{sub 2} fibers sensor at the temperature above 600 °C. Thermal radiation peaks are assigned with f-f transition of Tm{sup 3+} ion, {sup 1}D{sub 2}-{sup 3}H{sub 6}, and {sup 1}G{sub 4}-{sup 3}H{sub 6}. Peak intensity of thermal radiation from Tm{sup 3+} ion increases with temperature. Intensity ratio of thermal radiation peaks atmore » λ = 690 nm against that at λ = 790 nm, I{sub 790/690}, is suitable for the temperature measurement above 750 °C. Two-dimensional temperature distribution in a flame is successfully evaluated by Tm end doped SiO{sub 2} fiber sensor.« less

Structural and Functional Importance of Transmembrane Domain 3 (TM3) in the Aspartate:Alanine Antiporter AspT: Topology and Function of the Residues of TM3 and Oligomerization of AspT▿

PubMed Central

Nanatani, Kei; Maloney, Peter C.; Abe, Keietsu

2009-01-01

AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrate translocation pathway that includes the binding site for the substrates. To elucidate the role of TM3 in the transport process, we carried out cysteine-scanning mutagenesis. The substitutions of tyrosine 75 and serine 84 had the strongest inhibitory effects on transport (initial rates of l-aspartate transport were below 15% of the rate for cysteine-less AspT). Considerable but less-marked effects were observed upon the replacement of methionine 70, phenylalanine 71, glycine 74, arginine 76, serine 83, and methionine 85 (initial rates between 15% and 30% of the rate for cysteine-less AspT). Introduced cysteine residues at the cytoplasmic half of TM3 could be labeled with Oregon green maleimide (OGM), whereas cysteines close to the periplasmic half (residues 64 to 75) were not labeled. These results suggest that TM3 has a hydrophobic core on the periplasmic half and that hydrophilic residues on the cytoplasmic half of TM3 participate in the formation of an aqueous cavity in membranes. Furthermore, the presence of l-aspartate protected the cysteine introduced at glycine 62 against a reaction with OGM. In contrast, l-aspartate stimulated the reactivity of the cysteine introduced at proline 79 with OGM. These results demonstrate that TM3 undergoes l-aspartate-induced conformational alterations. In addition, nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis analyses and a glutaraldehyde cross-linking assay suggest that functional AspT forms homo-oligomers as a

Structural and functional importance of transmembrane domain 3 (TM3) in the aspartate:alanine antiporter AspT: topology and function of the residues of TM3 and oligomerization of AspT.

PubMed

Nanatani, Kei; Maloney, Peter C; Abe, Keietsu

2009-04-01

AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrate translocation pathway that includes the binding site for the substrates. To elucidate the role of TM3 in the transport process, we carried out cysteine-scanning mutagenesis. The substitutions of tyrosine 75 and serine 84 had the strongest inhibitory effects on transport (initial rates of l-aspartate transport were below 15% of the rate for cysteine-less AspT). Considerable but less-marked effects were observed upon the replacement of methionine 70, phenylalanine 71, glycine 74, arginine 76, serine 83, and methionine 85 (initial rates between 15% and 30% of the rate for cysteine-less AspT). Introduced cysteine residues at the cytoplasmic half of TM3 could be labeled with Oregon green maleimide (OGM), whereas cysteines close to the periplasmic half (residues 64 to 75) were not labeled. These results suggest that TM3 has a hydrophobic core on the periplasmic half and that hydrophilic residues on the cytoplasmic half of TM3 participate in the formation of an aqueous cavity in membranes. Furthermore, the presence of l-aspartate protected the cysteine introduced at glycine 62 against a reaction with OGM. In contrast, l-aspartate stimulated the reactivity of the cysteine introduced at proline 79 with OGM. These results demonstrate that TM3 undergoes l-aspartate-induced conformational alterations. In addition, nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis analyses and a glutaraldehyde cross-linking assay suggest that functional AspT forms homo-oligomers as a

The Neuroscience of PowerPoint[TM

ERIC Educational Resources Information Center

Horvath, Jared Cooney

2014-01-01

Many concepts have been published relevant to improving the design of PowerPoint[TM] (PP) presentations for didactic purposes, including the redundancy, modality, and signaling principles of multimedia learning. In this article, we review the recent neuroimaging findings that have emerged elucidating the neural structures involved in many of these…

77 FR 40364 - Announcement of Requirements and Registration for Million Hearts TM

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-09

... Requirements and Registration for Million Hearts TM Caregiver Video Challenge AGENCY: Centers for Disease... announces the launch of The Million Hearts TM Caregiver Video Challenge. We invite people who play a role in... their stories of caregiving by creating original, compelling videos that are less than 2 minutes long...

Impacts of doping concentration on the saturable characteristics of Tm-Ho codoped fiber saturable absorber

NASA Astrophysics Data System (ADS)

Tao, Mengmeng; Feng, Guobin; Yu, Ting; Ye, Xisheng; Wang, Zhenbao; Shen, Yanlong; Zhao, Jun

2018-03-01

Impacts of Tm ion concentration and Ho ion concentration on the saturable behaviors of Tm-Ho codoped fiber saturable absorbers and the output characteristics of the passively Q-switched laser systems are investigated and analyzed both at the initial lasing state and the stable passive Q-switching state. Simulations show that, varying concentrations of Tm and Ho ions have different impacts on the temporal evolution processes but similar effects on the macroscopic characteristics of the laser system. The root for the impacts of dopant concentrations is the population of the 3H6 energy level and the cavity loss it induces. For Tm ions, the rise of the Tm concentration improves the population of the 3H6 energy level directly, while, for Ho ions, higher Ho concentration leads to larger recovery rate of the 3H6 energy level, thus increasing the population of the 3H6 energy level indirectly. As for limited total dopant concentration, the Tm:Ho concentration ratio can be optimized for different applications.

LD-cladding-pumped 50 pm linewidth Tm 3+ -doped silica fiber laser.

PubMed

Yunjun, Zhang; Baoquan, Yao; Youlun, Ju; Hui, Zhou; Yuezhu, Wang

2008-05-26

We report on a Tm(3+)-doped fiber laser source operating at 1936.4 nm with a very narrow linewidth (50 pm) laser output. Up to 2.4 W cw laser power was obtained from an 82 cm long Tm(3+)-doped multimode-core fiber cladding pumped by a 792 nm laser diode (LD). The fiber laser cavity included a high-reflective dichroic and a low-reflective FBG output coupler. The multimode fiber Bragg grating (FBG) transmission spectrum and output laser spectrum were measured. By adjusting the distance between the dichroic and the Tm(3+)-doped fiber end, the multipeak laser spectrum changed to a single-peak laser spectrum.

Spectroscopic properties of Tm3+/Al3+ co-doped sol-gel silica glass

NASA Astrophysics Data System (ADS)

Wang, Xue; Lou, Fengguang; Wang, Shikai; Yu, Chunlei; Chen, Danping; Hu, Lili

2015-04-01

Tm3+/Al3+ co-doped silica glass was prepared by sol-gel method combined with high temperature sintering. Glasses with compositions of xTm2O3-15xAl2O3-(100 - 16x) SiO2 (in mol%, x = 0.1, 0.3, 0.5, 0.8 and 1.0) were prepared. The high thulium doped silica glass was realized. Their spectroscopic parameters were calculated and analyzed by Judd-Ofelt theory. Large absorption cross section (4.65 × 10-21 cm2 at 1668 nm) and stimulated emission cross section (6.00 × 10-21 cm2 at 1812 nm), as well as low hydroxyl content (0.180 cm-1), long fluorescence lifetime (834 μs at 1800 nm), large σem × τrad (30.05 × 10-21 cm2 ms) and large relative intensity ratio of the 1.8 μm (3F4 → 3H6) to 1.46 (3H4 → 3F4) emissions (90.33) are achieved in this Tm3+/Al3+ co-doped silica glasses. According to emission characteristics, the optimum thulium doping concentration is around 0.8 mol%. The cross relaxation (CR) between ground and excited states of Tm3+ ions was used to explain the optimum thulium doping concentration. These results suggest that the sol-gel method is an effective way to prepare Tm3+ doped silica glass with high Tm3+ doping and prospective spectroscopic properties.

Technical note: patient-specific quality assurance methods for TomoDirect(TM) whole breast treatment delivery.

PubMed

Catuzzo, P; Zenone, F; Aimonetto, S; Peruzzo, A; Casanova Borca, V; Pasquino, M; Franco, P; La Porta, M R; Ricardi, U; Tofani, S

2012-07-01

To investigate the feasibility of implementing a novel approach for patient-specific QA of TomoDirect(TM) whole breast treatment. The most currently used TomoTherapy DQA method, consisting in the verification of the 2D dose distribution in a coronal or sagittal plane of the Cheese Phantom by means of gafchromic films, was compared with an alternative approach based on the use of two commercially available diode arrays, MapCHECK2(TM) and ArcCHECK(TM). The TomoDirect(TM) plans of twenty patients with a primary unilateral breast cancer were applied to a CT scan of the Cheese Phantom and a MVCT dataset of the diode arrays. Then measurements of 2D dose distribution were performed and compared with the calculated ones using the gamma analysis method with different sets of DTA and DD criteria (3%-3 mm, 3%-2 mm). The sensitivity of the diode arrays to detect delivery and setup errors was also investigated. The measured dose distributions showed excellent agreement with the TPS calculations for each detector, with averaged fractions of passed Γ values greater than 95%. The percentage of points satisfying the constraint Γ < 1 was significantly higher for MapCHECK2(TM) than for ArcCHECK(TM) and gafchromic films using both the 3%-3 mm and 3%-2 mm gamma criteria. Both the diode arrays show a good sensitivity to delivery and setup errors using a 3%-2 mm gamma criteria. MapCHECK2™ and ArcCHECK(TM) may fulfill the demands of an adequate system for TomoDirect(TM) patient-specific QA.

Asymmetric linear efficiency and bunching mechanisms of TM modes for electron cyclotron maser

NASA Astrophysics Data System (ADS)

Chang, T. H.; Huang, W. C.; Yao, H. Y.; Hung, C. L.; Chen, W. C.; Su, B. Y.

2017-02-01

This study examines the transverse magnetic (TM) waveguide modes, which have long been considered as the unsuitable ones for the operation of the electron cyclotron maser. The beam-wave coupling strength of the TM modes, as expected, is found to be relatively weak as compared with that of the transverse electric (TE) waveguide modes. Unlike TE modes, surprisingly, the linear behavior of the TM modes depends on the sign of the wave number kz. The negative kz has a much stronger linear efficiency than that of the positive kz. The bunching mechanism analysis further exhibits that the azimuthal bunching and axial bunching do not compete but cooperate with each other for the backward-wave operation (negative kz). The current findings are encouraging and imply that TM modes might be advantageous to the gyrotron backward-wave oscillators.

Wheat yield estimation at the farm level using TM Landsat and agrometeorological data

NASA Technical Reports Server (NTRS)

Rudorff, B. F. T.; Batista, G. T.

1991-01-01

A model for estimating wheat yields on the farm level was developed, that integrates the Landsat TM data and agrometeorological information. Results obtained for a test site in southern Brasil for years of 1986 and 1987 show that the vegetation index derived from Landsat TM could account for the 60 to 40 percent wheat-yield variability observed between the two crop years. Compared to results using either the Landsat TM vegetation index or the agrometeorological data alone, the joint use of both types of data in a single model yielded a significant improvement.

Genetic characterization and improved genotyping of the dysferlin-deficient mouse strain Dysf (tm1Kcam).

PubMed

Wiktorowicz, Tatiana; Kinter, Jochen; Kobuke, Kazuhiro; Campbell, Kevin P; Sinnreich, Michael

2015-01-01

Mouse models of dysferlinopathies are valuable tools with which to investigate the pathomechanisms underlying these diseases and to test novel therapeutic strategies. One such mouse model is the Dysf (tm1Kcam) strain, which was generated using a targeting vector to replace a 12-kb region of the dysferlin gene and which features a progressive muscular dystrophy. A prerequisite for successful animal studies using genetic mouse models is an accurate genotyping protocol. Unfortunately, the lack of robustness of currently available genotyping protocols for the Dysf (tm1Kcam) mouse has prevented efficient colony management. Initial attempts to improve the genotyping protocol based on the published genomic structure failed. These difficulties led us to analyze the targeted locus of the dysferlin gene of the Dysf (tm1Kcam) mouse in greater detail. In this study we resequenced and analyzed the targeted locus of the Dysf (tm1Kcam) mouse and developed a novel PCR protocol for genotyping. We found that instead of a deletion, the dysferlin locus in the Dysf (tm1Kcam) mouse carries a targeted insertion. This genetic characterization enabled us to establish a reliable method for genotyping of the Dysf (tm1Kcam) mouse, and thus has made efficient colony management possible. Our work will make the Dysf (tm1Kcam) mouse model more attractive for animal studies of dysferlinopathies.

Measurement, Ratios, and Graphing: Who Added the "Micro" to Gravity? An Educator Guide with Activities in Mathematics, Science, and Technology. NASA CONNECT[TM].

ERIC Educational Resources Information Center

National Aeronautics and Space Administration, Hampton, VA. Langley Research Center.

The NASA CONNECT series features 30-minute, instructional videos for students in grades 5-8 and teacher's guides that use aeronautics and space technology as the organizing theme. In this guide and videotape, National Aeronautics and Space Administration (NASA) researchers and scientists use measurement, ratios, and graphing to demonstrate the…

Use of the TM tasseled cap transform for interpretation of spectral contrasts in an urban scene

NASA Technical Reports Server (NTRS)

Goward, S. N.; Wharton, S. W.

1984-01-01

Investigations are being conducted with the objective to develop automated numerical image analysis procedures. In this context, an examination is performed of physically-based multispectral data transforms as a means to incorporate a priori knowledge of land radiance properties in the analysis process. A physically-based transform of TM observations was developed. This transform extends the Landsat MSS Tasseled Cap transform reported by Kauth and Thomas (1976) to TM data observations. The present study has the aim to examine the utility of the TM Tasseled Cap transform as applied to TM data from an urban landscape. The analysis conducted is based on 512 x 512 subset of the Washington, DC November 2, 1982 TM scene, centered on Springfield, VA. It appears that the TM tasseled cap transformation provides a good means to explain land physical attributes of the Washington scene. This result provides a suggestion regarding a direction by which a priori knowledge of landscape spectral patterns may be incorporated into numerical image analysis.

The properties of RE-TM magneto-optical films

NASA Astrophysics Data System (ADS)

Lee, Z. Y.; Miao, X. S.; Zhu, P.; Hu, Y. S.; Wan, D. F.; Dai, D. W.; Chen, S. B.; Lin, G. Q.

1992-09-01

In this paper, the magnetic, magneto-optical and galvonomagnetic properties, and their temperature dependence for LRE-TM SmCo, SmCoDy and HRE-TM TbFeCo magneto-optical films as high density recording media prepared by rf magnetron sputtering or evaporation are reported. By adding Dy to SmCo thin film, the SmCoDy thin film is more suitable for magneto-optical recording, its domain size being below 0.63 μm. The Kerr enhancement and corrosion protective effects of AIN and AlSiN for optimum design of the multi-layer structure of magneto-optical disk are described. The instruments of measuring the magneto-optical Kerr effect and magneto-optical recording domain characteristics of thin films are reviewed.

SYBR safeTM efficiently replaces ethidium bromide in Aspergillus fumigatus gene disruption.

PubMed

Canela, H M S; Takami, L A; Ferreira, M E S

2017-02-08

Invasive aspergillosis is a disease responsible for high mortality rates, caused mainly by Aspergillus fumigatus. The available drugs are limited and this disease continues to occur at an unacceptable frequency. Gene disruption is essential in the search for new drug targets. An efficient protocol for A. fumigatus gene disruption was described but it requires ethidium bromide, a genotoxic agent, for DNA staining. Therefore, the present study tested SYBR safe TM , a non-genotoxic DNA stain, in A. fumigatus gene disruption protocol. The chosen gene was cipC, which has already been disrupted successfully in our laboratory. A deletion cassette was constructed in Saccharomyces cerevisiae and used in A. fumigatus transformation. There was no statistical difference between the tested DNA stains. The success rate of S. cerevisiae transformation was 63.3% for ethidium bromide and 70% for SYBR safe TM . For A. fumigatus gene disruption, the success rate for ethidium bromide was 100 and 97% for SYBR safe TM . In conclusion, SYBR safe TM efficiently replaced ethidium bromide, making this dye a safe and efficient alternative for DNA staining in A. fumigatus gene disruption.

In vivo tmRNA protection by SmpB and pre-ribosome binding conformation in solution

PubMed Central

Ranaei-Siadat, Ehsan; Mérigoux, Cécile; Seijo, Bili; Ponchon, Luc; Saliou, Jean-Michel; Bernauer, Julie; Sanglier-Cianférani, Sarah; Dardel, Fréderic

2014-01-01

TmRNA is an abundant RNA in bacteria with tRNA and mRNA features. It is specialized in trans-translation, a translation rescuing system. We demonstrate that its partner protein SmpB binds the tRNA-like region (TLD) in vivo and chaperones the fold of the TLD-H2 region. We use an original approach combining the observation of tmRNA degradation pathways in a heterologous system, the analysis of the tmRNA digests by MS and NMR, and co-overproduction assays of tmRNA and SmpB. We study the conformation in solution of tmRNA alone or in complex with one SmpB before ribosome binding using SAXS. Our data show that Mg2+ drives compaction of the RNA structure and that, in the absence of Mg2+, SmpB has a similar effect albeit to a lesser extent. Our results show that tmRNA is intrinsically structured in solution with identical topology to that observed on complexes on ribosomes which should facilitate its subsequent recruitment by the 70S ribosome, free or preloaded with one SmpB molecule. PMID:25135523

Comparative Genomics of Candidate Phylum TM6 Suggests That Parasitism Is Widespread and Ancestral in This Lineage

PubMed Central

Yeoh, Yun Kit; Sekiguchi, Yuji; Parks, Donovan H.; Hugenholtz, Philip

2016-01-01

Candidate phylum TM6 is a major bacterial lineage recognized through culture-independent rRNA surveys to be low abundance members in a wide range of habitats; however, they are poorly characterized due to a lack of pure culture representatives. Two recent genomic studies of TM6 bacteria revealed small genomes and limited gene repertoire, consistent with known or inferred dependence on eukaryotic hosts for their metabolic needs. Here, we obtained additional near-complete genomes of TM6 populations from agricultural soil and upflow anaerobic sludge blanket reactor metagenomes which, together with the two publicly available TM6 genomes, represent seven distinct family level lineages in the TM6 phylum. Genome-based phylogenetic analysis confirms that TM6 is an independent phylum level lineage in the bacterial domain, possibly affiliated with the Patescibacteria superphylum. All seven genomes are small (1.0–1.5 Mb) and lack complete biosynthetic pathways for various essential cellular building blocks including amino acids, lipids, and nucleotides. These and other features identified in the TM6 genomes such as a degenerated cell envelope, ATP/ADP translocases for parasitizing host ATP pools, and protein motifs to facilitate eukaryotic host interactions indicate that parasitism is widespread in this phylum. Phylogenetic analysis of ATP/ADP translocase genes suggests that the ancestral TM6 lineage was also parasitic. We propose the name Dependentiae (phyl. nov.) to reflect dependence of TM6 bacteria on host organisms. PMID:26615204

A Taiwanese Mandarin Main Concept Analysis (TM-MCA) for quantification of aphasic oral discourse.

PubMed

Kong, Anthony Pak-Hin; Yeh, Chun-Chih

2015-01-01

Various quantitative systems have been proposed to examine aphasic oral narratives in English. A clinical tool for assessing discourse produced by Cantonese-speaking persons with aphasia (PWA), namely Main Concept Analysis (MCA), was developed recently for quantifying the presence, accuracy and completeness of a narrative. Similar tools for Mandarin speakers are currently absent. The first aim is to develop and establish the validity of the Taiwanese Mandarin Main Concept Analysis (TM-MCA) for the Mandarin-speaking population in Taiwan, given the paucity of related investigations. Another aim is to establish the influence of age and education level on Taiwanese Mandarin speakers' oral narrative abilities. The third purpose is to examine how well the TM-MCA could distinguish between native speakers with and without aphasia in Taiwan. The final aim is to examine the reliability and validity of the TM-MCA. Eight speech-language pathologists (SLPs) and eight neurologically intact participants were involved to establish the TM-MCA main concepts. Another 36 neurologically intact participants and 10 PWA participated to validate the TM-MCA by contrasting their performance. Both age and educational level affected the oral discourse performance among the neurologically intact adults. Significant differences on the TM-MCA measures were noted between the control group and the group with aphasia. Moreover, the degree of aphasia significantly affected the oral discourse of PWA. The TM-MCA is a culturally appropriate quantitative system for the Taiwanese Mandarin population. It can be used to supplement standardized aphasia tests to help SLPs make more informative decisions not only on clinical diagnosis but also on treatment planning. © 2015 Royal College of Speech and Language Therapists.

Magnetic Properties of Al-Gd-TM Glass-Forming Alloys

NASA Astrophysics Data System (ADS)

Uporov, Sergey; Estemirova, Svetlana; Bykov, Viktor; Mitrofanov, Valentin

2016-01-01

We report results of magnetic studies of glass-forming alloys with nominal composition of Al86Gd6TM8 (where TM = Cu, Ni, Co, Fe, Mn, Cr, Ti, Zr, Mo, Ta) synthesized by arc-melting. X-ray diffraction analysis and vibrating sample magnetometry were applied to characterize the prepared samples. All the alloys exhibit antiferromagnetic ordering at low temperatures. In some compositions, we observed metamagnetic transitions in external magnetic fields up to 3 T. Analysis of the paramagnetic susceptibility of the considered Al-Gd-TM systems has revealed non-magnetic behavior of the transition metals. We found that the magnetic properties of the studied samples can be described satisfactorily using only the Gd trivalent ions. But in some cases the magnetic moments of gadolinium are slightly larger than the theoretical values, probably, because of an additional contribution of the 5 d electrons. The obtained results are discussed in framework of the assumptions of the strong s- p- d hybridization and frustrated magnetic states of gadolinium. We argue that the hybridization might be one of the main factors improving the glass-forming ability in these ternary alloys.

Detection of soil erosion within pinyon-juniper woodlands using Thematic Mapper (TM) data

NASA Technical Reports Server (NTRS)

Price, Kevin P.

1993-01-01

Multispectral measurements collected by Landsat Thematic Mapper (TM) were correlated with field measurements, direct soil loss estimates, and Universal Soil Loss Equation (USLE) estimates to determine the sensitivity of TM data to varying degrees of soil erosion in pinyon-juniper woodland in central Utah. TM data were also evaluated as a predictor of the USLE Crop Management C factor for pinyon-juniper woodlands. TM spectral data were consistently better predictors of soil erosion factors than any combination of field factors. TM data were more sensitive to vegetation variations than the USLE C factor. USLE estimates showed low annual rates of erosion which varied little among the study sites. Direct measurements of rate of soil loss using the SEDIMENT (Soil Erosion DIrect measureMENT) technique, indicated high and varying rates of soil loss among the sites since tree establishment. Erosion estimates from the USLE and SEDIMENT methods suggest that erosion rates have been severe in the past, but because significant amounts of soil have already been eroded, and the surface is now armored by rock debris, present erosion rates are lower. Indicators of accelerated erosion were still present on all sites, however, suggesting that the USLE underestimated erosion within the study area.

Lack of P4H-TM in mice results in age-related retinal and renal alterations.

PubMed

Leinonen, Henri; Rossi, Maarit; Salo, Antti M; Tiainen, Päivi; Hyvärinen, Jaana; Pitkänen, Marja; Sormunen, Raija; Miinalainen, Ilkka; Zhang, Chi; Soininen, Raija; Kivirikko, Kari I; Koskelainen, Ari; Tanila, Heikki; Myllyharju, Johanna; Koivunen, Peppi

2016-09-01

Age-related macular degeneration (AMD), affecting the retinal pigment epithelium (RPE), is the leading cause of blindness in middle-aged and older people in developed countries. Genetic and environmental risk factors have been identified, but no effective cure exists. Using a mouse model we show that a transmembrane prolyl 4-hydroxylase (P4H-TM), which participates in the oxygen-dependent regulation of the hypoxia-inducible factor (HIF), is a potential novel candidate gene for AMD. We show that P4h-tm had its highest expression levels in the mouse RPE and brain, heart, lung, skeletal muscle and kidney. P4h-tm -/- mice were fertile and had a normal life span. Lack of P4h-tm stabilized HIF-1α in cortical neurons under normoxia, while in hypoxia it increased the expression of certain HIF target genes in tissues with high endogenous P4h-tm expression levels more than in wild-type mice. Renal erythropoietin levels increased in P4h-tm -/- mice with aging, but the resulting ∼2-fold increase in erythropoietin serum levels did not lead to erythrocytosis. Instead, accumulation of lipid-containing lamellar bodies in renal tubuli was detected in P4h-tm -/- mice with aging, resulting in inflammation and fibrosis, and later glomerular sclerosis and albuminuria. Lack of P4h-tm was associated with retinal thinning, rosette-like infoldings and drusen-like structure accumulation in RPE with aging, as is characteristic of AMD. Photoreceptor recycling was compromised, and electroretinograms revealed functional impairment of the cone pathway in adult P4h-tm -/- mice and cone and rod deficiency in middle-aged mice. P4H-TM is therefore imperative for normal vision, and potentially a novel candidate for age-induced diseases, such as AMD. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Phenotypic and Physiological Characterization of the Epibiotic Interaction Between TM7x and Its Basibiont Actinomyces.

PubMed

Bor, Batbileg; Poweleit, Nicole; Bois, Justin S; Cen, Lujia; Bedree, Joseph K; Zhou, Z Hong; Gunsalus, Robert P; Lux, Renate; McLean, Jeffrey S; He, Xuesong; Shi, Wenyuan

2016-01-01

Despite many examples of obligate epibiotic symbiosis (one organism living on the surface of another) in nature, such an interaction has rarely been observed between two bacteria. Here, we further characterize a newly reported interaction between a human oral obligate parasitic bacterium TM7x (cultivated member of Candidatus Saccharimonas formerly Candidate Phylum TM7), and its basibiont Actinomyces odontolyticus species (XH001), providing a model system to study epiparasitic symbiosis in the domain Bacteria. Detailed microscopic studies indicate that both partners display extensive morphological changes during symbiotic growth. XH001 cells manifested as short rods in monoculture, but displayed elongated and hyphal morphology when physically associated with TM7x. Interestingly, these dramatic morphological changes in XH001 were also induced in oxygen-depleted conditions, even in the absence of TM7x. Targeted quantitative real-time PCR (qRT-PCR) analyses revealed that both the physical association with TM7x as well as oxygen depletion triggered up-regulation of key stress response genes in XH001, and in combination, these conditions act in an additive manner. TM7x and XH001 co-exist with relatively uniform cell morphologies under nutrient-replete conditions. However, upon nutrient depletion, TM7x-associated XH001 displayed a variety of cell morphologies, including swollen cell body, clubbed-ends, and even cell lysis, and a large portion of TM7x cells transformed from ultrasmall cocci into elongated cells. Our study demonstrates a highly dynamic interaction between epibiont TM7x and its basibiont XH001 in response to physical association or environmental cues such as oxygen level and nutritional status, as reflected by their morphological and physiological changes during symbiotic growth.

Near Infrared Quantum Cutting Luminescence of Er3+/Tm3+ Ion Pairs in a Telluride Glass.

PubMed

Chen, Xiaobo; Li, Song; Hu, Lili; Wang, Kezhi; Zhao, Guoying; He, Lizhu; Liu, Jinying; Yu, Chunlei; Tao, Jingfu; Lin, Wei; Yang, Guojian; Salamo, Gregory J

2017-05-16

The multiphoton near-infrared, quantum cutting luminescence in Er 3+ /Tm 3+ co-doped telluride glass was studied. We found that the near-infrared 1800-nm luminescence intensity of (A) Er 3+ (8%)Tm 3+ (0.5%):telluride glass was approximately 4.4 to 19.5 times larger than that of (B) Tm 3+ (0.5%):telluride glass, and approximately 5.0 times larger than that of (C) Er 3+ (0.5%):telluride glass. Additionally, the infrared excitation spectra of the 1800 nm luminescence, as well as the visible excitation spectra of the 522 nm and 652 nm luminescence, of (A) Er 3+ (8%)Tm 3+ (0.5%):telluride glass are very similar to those of Er 3+ ions in (C) Er 3+ (0.5%):telluride glass, with respect to the shapes of their excitation spectral waveforms and peak wavelengths. Moreover, we found that there is a strong spectral overlap and energy transfer between the infrared luminescence of Er 3+ donor ions and the infrared absorption of Tm 3+ acceptor ions. The efficiency of this energy transfer { 4 I 13/2 (Er 3+ ) →  4 I 15/2 (Er 3+ ), 3 H 6 (Tm 3+ ) →  3 F 4 (Tm 3+ )} between the Er 3+ and Tm 3+ ions is approximately 69.8%. Therefore, we can conclude that the observed behaviour is an interesting multiphoton, near-infrared, quantum cutting luminescence phenomenon that occurs in novel Er 3+ -Tm 3+ ion pairs. These findings are significant for the development of next-generation environmentally friendly germanium solar cells, and near-to-mid infrared (1.8-2.0 μm) lasers pumped by GaN light emitting diodes.

Diode-pumped mode-locked femtosecond Tm:CLNGG disordered crystal laser.

PubMed

Ma, J; Xie, G Q; Gao, W L; Yuan, P; Qian, L J; Yu, H H; Zhang, H J; Wang, J Y

2012-04-15

A diode-end-pumped passively mode-locked femtosecond Tm-doped calcium lithium niobium gallium garnet (Tm:CLNGG) disordered crystal laser was demonstrated for the first time to our knowledge. With a 790 nm laser diode pumping, stable CW mode-locking operation was obtained by using a semiconductor saturable absorber mirror. The disordered crystal laser generated mode-locked pulses as short as 479 fs, with an average output power of 288 mW, and repetition rate of 99 MHz in 2 μm spectral region. © 2012 Optical Society of America

Preliminary study of Kelso Dunes using AVIRIS, TM, and AIRSAR

NASA Technical Reports Server (NTRS)

Xu, Pung; Blumberg, Dan G.; Greeley, Ronald

1995-01-01

Remote sensing of sand dunes helps in the understanding of aeolian process and provides important information about the regional geologic history, environmental change, and desertification. Remotely sensed data combined with field studies are valuable in studying dune morphology, regional aeolian dynamics, and aeolian depositional history. In particular, active and inactive sands of the Kelso Dunes have been studied using landsat TM and AIRSAR. In this report, we describe the use of AVIRIS data to study the Kelso dunes and to compare the AVIRIS information with that from TM and AIRSAR.

BOREAS Level-3p Landsat TM Imagery: Geocoded and Scaled At-sensor Radiance

NASA Technical Reports Server (NTRS)

Nickeson, Jaime; Knapp, David; Newcomer, Jeffrey A.; Hall, Forrest G. (Editor); Cihlar, Josef

2000-01-01

For BOReal Ecosystem-Atmosphere Study (BOREAS), the level-3p Landsat Thematic Mapper (TM) data were used to supplement the level-3s Landsat TM products. Along with the other remotely sensed images, the Landsat TM images were collected in order to provide spatially extensive information over the primary study areas. This information includes radiant energy, detailed land cover, and biophysical parameter maps such as Fraction of Photosynthetically Active Radiation (FPAR) and Leaf Area Index (LAI). Although very similar to the level-3s Landsat TM products, the level-3p images were processed with ground control information, which improved the accuracy of the geographic coordinates provided. Geographically, the level-3p images cover the BOREAS Northern Study Area (NSA) and Southern Study Area (SSA). Temporally, the four images cover the period of 20-Aug-1988 to 07-Jun-1994. Except for the 07-Jun-1994 image, which contains seven bands, the other three contain only three bands.

Apoptosis-like cell death in Leishmania donovani treated with KalsomeTM10, a new liposomal amphotericin B

PubMed Central

Shadab, Md.; Jha, Baijayanti; Asad, Mohammad; Deepthi, Makaraju; Kamran, Mohd.; Ali, Nahid

2017-01-01

Objective The present study aimed to elucidate the cell death mechanism in Leishmania donovani upon treatment with KalsomeTM10, a new liposomal amphotericin B. Methodology/Principal findings We studied morphological alterations in promastigotes through phase contrast and scanning electron microscopy. Phosphatidylserine (PS) exposure, loss of mitochondrial membrane potential and disruption of mitochondrial integrity was determined by flow cytometry using annexinV-FITC, JC-1 and mitotraker, respectively. For analysing oxidative stress, generation of H2O2 (bioluminescence kit) and mitochondrial superoxide O2− (mitosox) were measured. DNA fragmentation was evaluated using terminal deoxyribonucleotidyl transferase mediated dUTP nick-end labelling (TUNEL) and DNA laddering assay. We found that KalsomeTM10 is more effective then Ambisome against the promastigote as well as intracellular amastigote forms. The mechanistic study showed that KalsomeTM10 induced several morphological alterations in promastigotes typical of apoptosis. KalsomeTM10 treatment showed a dose- and time-dependent exposure of PS in promastigotes. Further, study on mitochondrial pathway revealed loss of mitochondrial membrane potential as well as disruption in mitochondrial integrity with depletion of intracellular pool of ATP. KalsomeTM10 treated promastigotes showed increased ROS production, diminished GSH levels and increased caspase-like activity. DNA fragmentation and cell cycle arrest was observed in KalsomeTM10 treated promastigotes. Apoptotic DNA fragmentation was also observed in KalsomeTM10 treated intracellular amastigotes. KalsomeTM10 induced generation of ROS and nitric oxide leads to the killing of the intracellular parasites. Moreover, endocytosis is indispensable for KalsomeTM10 mediated anti-leishmanial effect in host macrophage. Conclusions KalsomeTM10 induces apoptotic-like cell death in L. donovani parasites to exhibit its anti-leishmanial function. PMID:28170432

High power resonant pumping of Tm-doped fiber amplifiers in core- and cladding-pumped configurations.

PubMed

Creeden, Daniel; Johnson, Benjamin R; Rines, Glen A; Setzler, Scott D

2014-11-17

We have demonstrated ultra-high efficiency amplification in Tm-doped fiber with both core- and cladding-pumped configurations using a resonant tandem-pumping approach. These Tm-doped fiber amplifiers are pumped in-band with a 1908 nm Tm-doped fiber laser and operate at 1993 nm with >90% slope efficiency. In a core-pumped configuration, we have achieved 92.1% slope efficiency and 88.4% optical efficiency at 41 W output power. In a cladding-pumped configuration, we have achieved 123.1 W of output power with 90.4% optical efficiency and a 91.6% slope efficiency. We believe these are the highest optical efficiencies achieved in a Tm-doped fiber amplifier operating in the 2-micron spectral region.

Optical transitions of Tm3+ in oxyfluoride glasses and compositional and thermal effect on upconversion luminescence of Tm3+/Yb3+-codoped oxyfluoride glasses.

PubMed

Feng, Li; Wu, Yinsu; Liu, Zhuo; Guo, Tao

2014-01-24

Optical properties of Tm(3+)-doped SiO2-BaF2-ZnF2 glasses have been investigated on the basis of the Judd-Ofelt theory. Judd-Ofelt intensity parameters, radiative transition probabilities, fluorescence branching ratios and radiative lifetimes have been calculated for different glass compositions. Upconversion emissions were observed in Tm(3+)/Yb(3+)-codoped SiO2-BaF2-ZnF2 glasses under 980 nm excitation. The effects of composition, concentration of the doping ions, temperature, and excitation pump power on the upconversion emissions were also systematically studied. Copyright © 2013 Elsevier B.V. All rights reserved.

Doors to Discovery [TM]. WWC Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2009

2009-01-01

Doors to Discovery[TM], an early childhood curriculum, focuses on the development of children's vocabulary and expressive and receptive language through a learning process called "shared literacy," where adults and children work together to develop literacy-related skills. Literacy activities, organized into thematic units, encourage children's…

NASA's ATM Technology Demonstration-1: Integrated Concept of Arrival Operations

NASA Technical Reports Server (NTRS)

Baxley, Brian T.; Swenson, Harry N.; Prevot, Thomas; Callantine, Todd J.

2012-01-01

This paper describes operations and procedures envisioned for NASA s Air Traffic Management (ATM) Technology Demonstration #1 (ATD-1). The ATD-1 Concept of Operations (ConOps) demonstration will integrate three NASA technologies to achieve high throughput, fuel-efficient arrival operations into busy terminal airspace. They are Traffic Management Advisor with Terminal Metering (TMA-TM) for precise time-based schedules to the runway and points within the terminal area, Controller-Managed Spacing (CMS) decision support tools for terminal controllers to better manage aircraft delay using speed control, and Flight deck Interval Management (FIM) avionics and flight crew procedures to conduct airborne spacing operations. The ATD-1 concept provides de-conflicted and efficient operations of multiple arrival streams of aircraft, passing through multiple merge points, from top-of-descent (TOD) to touchdown. It also enables aircraft to conduct Optimized Profile Descents (OPDs) from en route altitude to the runway, using primarily speed control to maintain separation and schedule. The ATD-1 project is currently addressing the challenges of integrating the three technologies, and implantation into an operational environment. Goals of the ATD-1 demonstration include increasing the throughput of high-density airports, reducing controller workload, increasing efficiency of arrival operations and the frequency of trajectory-based operations, and promoting aircraft ADS-B equipage.

In vivo tmRNA protection by SmpB and pre-ribosome binding conformation in solution.

PubMed

Ranaei-Siadat, Ehsan; Mérigoux, Cécile; Seijo, Bili; Ponchon, Luc; Saliou, Jean-Michel; Bernauer, Julie; Sanglier-Cianférani, Sarah; Dardel, Fréderic; Vachette, Patrice; Nonin-Lecomte, Sylvie

2014-10-01

TmRNA is an abundant RNA in bacteria with tRNA and mRNA features. It is specialized in trans-translation, a translation rescuing system. We demonstrate that its partner protein SmpB binds the tRNA-like region (TLD) in vivo and chaperones the fold of the TLD-H2 region. We use an original approach combining the observation of tmRNA degradation pathways in a heterologous system, the analysis of the tmRNA digests by MS and NMR, and co-overproduction assays of tmRNA and SmpB. We study the conformation in solution of tmRNA alone or in complex with one SmpB before ribosome binding using SAXS. Our data show that Mg(2+) drives compaction of the RNA structure and that, in the absence of Mg(2+), SmpB has a similar effect albeit to a lesser extent. Our results show that tmRNA is intrinsically structured in solution with identical topology to that observed on complexes on ribosomes which should facilitate its subsequent recruitment by the 70S ribosome, free or preloaded with one SmpB molecule. © 2014 Ranaei-Siadat et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

High-field magnetoelasticity of Tm2Co17 and comparison with Er2Co17

NASA Astrophysics Data System (ADS)

Andreev, A. V.; Zvyagin, A. A.; Skourski, Y.; Yasin, S.; Zherlitsyn, S.

2017-11-01

Acoustic properties (ultrasound velocity and attenuation) and magnetostriction were measured in pulsed fields up to 60 T applied along the c axis of Tm2Co17 single crystal. Similar to Er2Co17, the transition in Tm2Co17 is accompanied by clear anomalies in the sound velocity. The observed 0.3% jump of the sound velocity at the transition is negative in Tm2Co17, whereas it is positive in Er2Co17. The magnetostriction at the transition also differs very much from that in Er2Co17. In Tm2Co17, the transition is accompanied by a smooth minimum of 0.15 × 10-4 in longitudinal magnetostriction whereas in Er2Co17 by a very sharp expansion of much larger magnitude (1.2 × 10-4). In the transverse mode, the effect in Tm2Co17 looks as very broad minimum of low amplitude (<0.1 × 10-4) whereas in Er2Co17 as very sharp and large shrinkage (2.6 × 10-4). Thus, both the magnetoacoustics and magnetostriction are rather different in Tm2Co17 and Er2Co17. This supports different nature of the field-induced transitions in these compounds.

Survey of Long-Term Technology Forecasting Methodologies

DTIC Science & Technology

2002-11-01

called for include an integrated demand information architecture, a TransAtmospheric Vehicle (TAV), and development of a space-based laser ( SBL ) system...Program,” NASA TM-1998-208400, 1998 (see http://www.grc.nasa.gov/WWW/ bpp /TM-1998-208400.htm ). Also available in Missions to the Outer Solar System and...November 1997, Presented at Plenary Session III Views of Future STAIF, Jan. 27, 1998, Albuquerque, NM (see http://www.lerc.nasa.gov/ WWW/ bpp /TM-97-206241

The NASA Lightning Nitrogen Oxides Model (LNOM): Recent Updates and Applications

NASA Technical Reports Server (NTRS)

Koshak, William; Peterson, Harold; Biazar, Arastoo; Khan, Maudood; Wang, Lihua; Park, Yee-Hun

2011-01-01

Improvements to the NASA Marshall Space Flight Center Lightning Nitrogen Oxides Model (LNOM) and its application to the Community Multiscale Air Quality (CMAQ) modeling system are presented. The LNOM analyzes Lightning Mapping Array (LMA) and National Lightning Detection Network(tm) (NLDN) data to estimate the raw (i.e., unmixed and otherwise environmentally unmodified) vertical profile of lightning NOx (= NO + NO2). Lightning channel length distributions and lightning 10-m segment altitude distributions are also provided. In addition to NOx production from lightning return strokes, the LNOM now includes non-return stroke lightning NOx production due to: hot core stepped and dart leaders, stepped leader corona sheath, K-changes, continuing currents, and M-components. The impact of including LNOM-estimates of lightning NOx for an August 2006 run of CMAQ is discussed.

DAG-TM Concept Element 11 CNS Performance Assessment: ADS-B Performance in the TRACON

NASA Technical Reports Server (NTRS)

Raghavan, Rajesh S.

2004-01-01

Distributed Air/Ground (DAG) Traffic Management (TM) is an integrated operational concept in which flight deck crews, air traffic service providers and aeronautical operational control personnel use distributed decision-making to enable user preferences and increase system capacity, while meeting air traffic management (ATM) safety requirements. It is a possible operational mode under the Free Flight concept outlined by the RTCA Task Force 3. The goal of DAG-TM is to enhance user flexibility/efficiency and increase system capacity, without adversely affecting system safety or restricting user accessibility to the National Airspace System (NAS). DAG-TM will be accomplished with a human-centered operational paradigm enabled by procedural and technological innovations. These innovations include automation aids, information sharing and Communication, Navigation, and Surveillance (CNS) / ATM technologies. The DAG-TM concept is intended to eliminate static restrictions to the maximum extent possible. In this paradigm, users may plan and operate according to their preferences - as the rule rather than the exception - with deviations occurring only as necessary. The DAG-TM concept elements aim to mitigate the extent and impact of dynamic NAS constraints, while maximizing the flexibility of airspace operations

Improvement in absolute calibration accuracy of Landsat-5 TM with Landsat-7 ETM+ data

USGS Publications Warehouse

Chander, G.; Markham, B.L.; Micijevic, E.; Teillet, P.M.; Helder, D.L.; ,

2005-01-01

The ability to detect and quantify changes in the Earth's environment depends on satellites sensors that can provide calibrated, consistent measurements of Earth's surface features through time. A critical step in this process is to put image data from subsequent generations of sensors onto a common radiometric scale. To evaluate Landsat-5 (L5) Thematic Mapper's (TM) utility in this role, image pairs from the L5 TM and Landsat-7 (L7) Enhanced Thematic Mapper Plus (ETM+) sensors were compared. This approach involves comparison of surface observations based on image statistics from large common areas observed eight days apart by the two sensors. The results indicate a significant improvement in the consistency of L5 TM data with respect to L7 ETM+ data, achieved using a revised Look-Up-Table (LUT) procedure as opposed to the historical Internal Calibrator (IC) procedure previously used in the L5 TM product generation system. The average percent difference in reflectance estimates obtained from the L5 TM agree with those from the L7 ETM+ in the Visible and Near Infrared (VNIR) bands to within four percent and in the Short Wave Infrared (SWIR) bands to within six percent.

Luminescence properties of Tm3+ ions single-doped YF3 materials in an unconventional excitation region.

PubMed

Chen, Yuan; Liu, Qing; Lin, Han; Yan, Xiaohong

2018-05-01

According to the spectral distribution of solar radiation at the earth's surface, under the excitation region of 1150 to 1350 nm, the up-conversion luminescence of Tm 3+ ions was investigated. The emission bands were matched well with the spectral response region of silicon solar cells, achieved by Tm 3+ ions single-doped yttrium fluoride (YF 3 ) phosphor, which was different from the conventional Tm 3+ /Yb 3+ ion couple co-doped materials. Additionally, the similar emission bands of Tm 3+ ions were achieved under excitation in the ultraviolet region. It is expected that via up-conversion and down-conversion routes, Tm 3+ -sensitized materials could convert photons to the desired wavelengths in order to reduce the energy loss of silicon solar cells, thereby enhancing the photovoltaic efficiency. Copyright © 2018 John Wiley & Sons, Ltd.

77 FR 69548 - Price for the 2012 Limited Edition Silver Proof SetTM

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-19

... DEPARTMENT OF THE TREASURY United States Mint Price for the 2012 Limited Edition Silver Proof Set TM AGENCY: United States Mint, Department of the Treasury. ACTION: Notice. SUMMARY: The United States Mint is announcing a price of $149.95 for the 2012 Limited Edition Silver Proof Set TM . FOR FURTHER...

TM4SF5 promotes metastatic behavior of cells in 3D extracellular matrix gels by reducing dependency on environmental cues

PubMed Central

Nam, Seo Hee; Cheong, Jin-Gyu; Jeong, Doyoung; Lee, Seo-Jin; Pan, Cheol-Ho; Jung, Jae Woo; Kim, Hye-Jin; Ryu, Jihye; Kim, Ji Eon; Kim, Somi; Cho, Chang Yun; Kang, Min-Kyung; Lee, Kyung-Min; Lee, Jung Weon

2017-01-01

Transmembrane 4 L six family member 5 (TM4SF5) is highly expressed in hepatocellular carcinoma tissues and enhances migration in two-dimensional environments. Here, we investigated how TM4SF5 is involved in diverse pro-metastatic phenotypes in in vivo-like three-dimensional (3D) extracellular matrix gels. TM4SF5-positive cells aggressively formed invasive foci in 3D Matrigel, depending on TM4SF5-mediated signaling activity, cytoskeletal organization, and matrix metallopeptidase (MMP) 2-mediated extracellular remodeling, whereas TM4SF5-null cells did not. The TM4SF5-null cells did, however, form invasive foci in 3D Matrigel following inhibition of Rho-associated protein kinase or addition of collagen I, suggesting that collagen I compensated for TM4SF5 expression. Similarly, TM4SF5-positive cells expressing vascular endothelial-cadherin formed network-like vasculogenic mimicry in 3D Matrigel and collagen I mixture gels, whereas TM4SF5-negative cells in the mixture gels displayed the network structures only upon further treatment with epidermal growth factor. The foci formation also required MMP2-mediated remodeling of the extracellular matrix. Co-cultures exhibited TM4SF5-positive or cancer-associated fibroblasts at the outward edges of TM4SF5-null cell clusters. Compared with TM4SF5-null cells, TM4SF5-positive cells in 3D collagen gels showed a more invasive outgrowth with dramatic invadopodia. These observations suggest that TM4SF5 plays roles in the promotion of diverse metastatic properties with fewer environmental requirements than TM4SF5-negative cells. PMID:29137358

Compendium of NASA data base for the global tropospheric experiment's Pacific Exploratory Mission West-B (PEM West-B)

NASA Technical Reports Server (NTRS)

Gregory, Gerald L.; Scott, A. Donald, Jr.

1995-01-01

This compendium describes aircraft data that are available from NASA's Pacific Exploratory Mission West-B (PEM West-B). PEM West is a component of the International Global Atmospheric Chemistry's (IGAC) East Asia/North Pacific Regional Study (APARE) project. Objectives of PEM West are to investigate the atmospheric chemistry of ozone over the northwest Pacific -- natural budgets and the impact of anthropogenic/continental sources; and to investigate sulfur chemistry -- continental and marine sulfur sources. The PEM West program encompassed two expeditions. PEM West-A was conducted in September 1991 during which the predominance of tropospheric air was from mid-Pacific (marine) regions, but (at times) was modified by Asian outflow. PEM West-B was conducted during February 1994, a period characterized by maximum Asian outflow. Results from PEM West-A and B are public domain. PEM West-A data are summarized in NASA TM 109177 (published February 1995). Flight experiments were based at Guam, Hong Kong, and Japan. This document provides a representation of NASA DC-8 aircraft data that are available from NASA Langley's Distributed Active Archive Center (DAAC). The DAAC includes numerous other data such as meteorological and modeling products, results from surface studies, satellite observations, and sonde releases.

75 FR 61480 - Cobscook Bay OCGenTM

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12711-004] Cobscook Bay.... The proposed project would consist of: (1) 5 TidGen TM hydrokinetic tidal devices each consisting of a... kilowatts; (2) a 4,530-foot-long submersible cable connecting the turbine-generating units of each device to...

75 FR 61479 - Western Passage OCGenTM

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-05

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 12680-004] Western Passage...' express permission. The proposed project would consist of: (1) 2 OCGen\\TM\\ hydrokinetic tidal devices each... turbine-generating units of each device to a shore station; (5) a 2,800-foot-long, 34.5-kilovolt...

Microtox(TM) characterization of foundry sand residuals

USGS Publications Warehouse

Bastian, K.C.; Alleman, J.E.

1998-01-01

Although foundry residuals, consisting mostly of waste Sands, represent a potentially attractive, high-volume resource for beneficial reuse applications (e.g. highway embankment construction), prospective end users are understandably concerned about unforeseen liabilities stemming from the use of these residuals. This paper, therefore, focuses on the innovative use of a microbial bioassay as a means of developing a characterization of environmental suitability extending beyond the analytical coverage already provided by mandated chemical-specific tests (i.e., TCLP, etc.). Microtox(TM) bioassays were conducted on leachates derived from residuals obtained at a wide range of facilities, including: 11 gray and ductile iron foundries plus one each steel and aluminum foundries. In addition, virgin sand samples were used to establish a relative 'natural' benchmark against which the waste foundry sands could then be compared in terms of their apparent quality. These bioassay tests were able to effectively 'fingerprint' those residuals whose bioassay behavior was comparable to that of virgin materials. In fact, the majority of gray and ductile iron foundry residuals tested during this reported study elicited Microtox(TM) response levels which fell within or below the virgin sand response range, consequently providing another quantifiable layer of Support for this industry's claim that their sands are 'cleaner than dirt.' However, negative Microtox(TM) responses beyond that of the virgin sands were observed with a number of foundry samples (i.e. four of the 11 gray or ductile iron sands plus both non-iron sands). Therefore, the latter results would suggest that these latter residuals be excluded from beneficial reuse for the immediate future, at least until the cause and nature of this negative response has been further identified.

Self-renewal and circulating capacities of metastatic hepatocarcinoma cells required for collaboration between TM4SF5 and CD44

PubMed Central

Lee, Doohyung; Lee, Jung Weon

2015-01-01

Tumor metastasis involves circulating and tumor-initiating capacities of metastatic cancer cells. Hepatic TM4SF5 promotes EMT for malignant growth and migration. Hepatocellular carcinoma (HCC) biomarkers remain unexplored for metastatic potential throughout metastasis. Here, novel TM4SF5/CD44 interaction-mediated self-renewal and circulating tumor cell (CTC) capacities were mechanistically explored. TM4SF5-dependent sphere growth was correlated with CD133+, CD24-, ALDH activity, and a physical association between CD44 and TM4SF5. The TM4SF5/CD44 interaction activated c-Src/STAT3/ Twist1/ B mi1 signaling for spheroid formation, while disturbing the interaction, expression, or activity of any component in this signaling pathway inhibited spheroid formation. In serial xenografts of less than 5,000 cells/injection, TM4SF5-positive tumors exhibited locally-increased CD44 expression, suggesting tumor cell differentiation. TM4SF5-positive cells were identified circulating in blood 4 to 6 weeks after orthotopic liver-injection. Anti-TM4SF reagents blocked their metastasis to distal intestinal organs. Altogether, our results provide evidence that TM4SF5 promotes self-renewal and CTC properties supported by CD133+/TM4SF5+/CD44+(TM4SF5-bound)/ALDH+/ CD24- markers during HCC metastasis. [BMB Reports 2015; 48(3): 127-128] PMID:25772760

How Do Raters from India Perform in Scoring the TOEFL iBT[TM] Speaking Section and What Kind of Training Helps? TOEFL iBT[TM] Research Report. RR-09-31

ERIC Educational Resources Information Center

Xi, Xiaoming; Mollaun, Pam

2009-01-01

This study investigated the scoring of the Test of English as a Foreign Language[TM] Internet-based Test (TOEFL iBT[TM]) Speaking section by bilingual or multilingual speakers of English and 1 or more Indian languages. We explored the extent to which raters from India, after being trained and certified, were able to score the Speaking section for…

Luminescence mechanism and energy transfer in doubly-doped BaY2F8:Tm,Nd VUV scintillator

NASA Astrophysics Data System (ADS)

Pejchal, J.; Nikl, M.; Moretti, F.; Vedda, A.; Fukuda, K.; Kawaguchi, N.; Yanagida, T.; Yokota, Y.; Yoshikawa, A.

2010-11-01

Doubly-doped BaY2F8:Tm,Nd scintillation crystals were grown by modified micro-pulling-down method. Nd co-doping was chosen to enhance the energy transfer from the host lattice to the Nd3+ luminescence center via the 5d-levels of Tm3+, due to the overlap of Tm3+ 5d-4f emission spectrum with the Nd3+ 4f-5d absorption. The energy transfer was clearly evidenced in the BaY2F8:Tm,Nd. This process is not complicated by an energy migration to killer centers and/or cross-relaxation. The radioluminescence process is complicated by an energy transfer from the host lattice exciton states to the lower f-levels of Tm3+ ion.

DigitalGlobe(TM) Incorporated Corporate and System Update

NASA Technical Reports Server (NTRS)

Thomassie, Brett

2007-01-01

This viewgraph presentation describes a system update of Quickbird, the world's highest resolution commercial imaging satellite, operated by DigitalGlobe (TM) Incorporated. A satellite comparison of Quickbird, WorldView-60, and WorldView-110 is also presented.

tmBioC: improving interoperability of text-mining tools with BioC.

PubMed

Khare, Ritu; Wei, Chih-Hsuan; Mao, Yuqing; Leaman, Robert; Lu, Zhiyong

2014-01-01

The lack of interoperability among biomedical text-mining tools is a major bottleneck in creating more complex applications. Despite the availability of numerous methods and techniques for various text-mining tasks, combining different tools requires substantial efforts and time owing to heterogeneity and variety in data formats. In response, BioC is a recent proposal that offers a minimalistic approach to tool interoperability by stipulating minimal changes to existing tools and applications. BioC is a family of XML formats that define how to present text documents and annotations, and also provides easy-to-use functions to read/write documents in the BioC format. In this study, we introduce our text-mining toolkit, which is designed to perform several challenging and significant tasks in the biomedical domain, and repackage the toolkit into BioC to enhance its interoperability. Our toolkit consists of six state-of-the-art tools for named-entity recognition, normalization and annotation (PubTator) of genes (GenNorm), diseases (DNorm), mutations (tmVar), species (SR4GN) and chemicals (tmChem). Although developed within the same group, each tool is designed to process input articles and output annotations in a different format. We modify these tools and enable them to read/write data in the proposed BioC format. We find that, using the BioC family of formats and functions, only minimal changes were required to build the newer versions of the tools. The resulting BioC wrapped toolkit, which we have named tmBioC, consists of our tools in BioC, an annotated full-text corpus in BioC, and a format detection and conversion tool. Furthermore, through participation in the 2013 BioCreative IV Interoperability Track, we empirically demonstrate that the tools in tmBioC can be more efficiently integrated with each other as well as with external tools: Our experimental results show that using BioC reduces >60% in lines of code for text-mining tool integration. The tmBioC toolkit

Enhanced Photoluminescent Properties and Crystalline Morphology of LiBaPO4:Tm3+ Phosphor through Microwave Sintering Method

PubMed Central

Lai, Hsuan-Lin; Weng, Min-Hang; Yang, Ru-Yuan; Chang, Shoou-Jinn

2016-01-01

An investigation of the photoluminescent properties and crystalline morphology of blue emitting LiBa1−xPO4:xTm3+ phosphors with various concentrations (x = 0.005–0.030) of Tm3+ ions were synthesized by microwave sintering. For comparison, the LiBa1−xPO4:xTm3+ powders sintered at the same sintering condition but in a conventional furnace were also investigated. LiBaPO4 without second phase was formed no matter which furnace was used. More uniform grain size distributions are obtained by microwave sintering. When the concentration of Tm3+ ion was x = 0.015, the luminescence intensity reached a maximum value, and then decreased with the increases of the Tm3+ concentration due to concentration quenching effect. The microwave sintering significantly enhanced the emission intensity of LiBa1−xPO4:xTm3+ phosphors. Additionally, the d-d interaction is the key mechanism of concentration quenching for LiBaPO4:Tm3+. The chromaticity (x, y) for all LiBa1−xPO4:xTm3+ phosphors are located at (0.16, 0.05), which will be classified as a blue region. PMID:28773483

Tunable luminescence mediated by energy transfer in Tm3+/Dy3+ co-doped phosphate glasses under UV excitation

NASA Astrophysics Data System (ADS)

Chen, Yong; Chen, Guohua; Liu, Xiangyu; Yuan, Changlai; Zhou, Changrong

2017-11-01

Tm3+/Dy3+ co-doped phosphate glasses for white light-emitting diodes were synthesized by a conventional melting-quenching method. A spectroscopic research based on optical, photoluminescence spectrum and decay time curves in Tm3+/Dy3+ co-doped phosphate glasses was carried out. The color of luminescence could be tuned by altering the concentrations of Tm3+ ions. Under UV light excitation, the CIE chromaticity coordinates (0.3471, 0.3374) and color correlate temperature (CCT = 4866.21 K) close to the standard white-light illumination (0.333, 0.333 and CCT = 5454.12 K) could be achieved in 0.4 Tm3+/0.6 Dy3+ (mol %) co-doped glass sample. The decrease of the Dy3+ emission decay time in existence of Tm3+ ascertained that non-radiative energy transfer from Dy3+ to Tm3+ occurred. Moreover, the research of energy transfers between Dy3+ and Tm3+ based on the Inokuti-Hirayama model revealed that an electric quadrupole-quadrupole interaction might be the predominant mechanism participated in the energy transfer. This finding suggests that the as-prepared Tm3+/Dy3+ co-doped phosphate glasses may be promising candidate for white LEDs and other display devices.

Bidirectional signaling between TM4SF5 and IGF1R promotes resistance to EGFR kinase inhibitors.

PubMed

Choi, Jungeun; Kang, Minkyung; Nam, Seo Hee; Lee, Gyu-Ho; Kim, Hye-Jin; Ryu, Jihye; Cheong, Jin Gyu; Jung, Jae Woo; Kim, Tai Young; Lee, Ho-Young; Lee, Jung Weon

2015-10-01

The membrane glycoprotein TM4SF5 (transmembrane 4 L6 family member 5), which is similar to the tetraspanins, is highly expressed in different cancers and causes epithelial-mesenchymal transition (EMT). TM4SF5 interacts with other membrane proteins during its pro-tumorigenic roles, presumably at tetraspanin-enriched microdomains (TEMs/TERMs). Here, we explored TM4SF5-mediated resistance against the clinically important EGFR kinase inhibitors, with regards to cooperation with other membrane proteins, particularly the insulin-like growth factor 1 receptor (IGF1R). Using cancer cells including NSCLC with TM4SF5 overexpression or IGF1R suppression in either normal 2 dimensional (2D), 3D aqueous spheroids, or 3D collagen I gels systems, the sensitivity to tyrosine kinase inhibitors (TKIs) were evaluated. We found that TM4SF5 and IGF1R transcriptionally modulated one another, with each protein promoting the expressions of the other. Expression of TM4SF5 in gefitinib-sensitive HCC827 cells caused resistance to erlotinib and gefitinib, but not to sorafenib [a platelet derived growth factor receptor (PDGFR) inhibitor]; whereas suppression of IGF1R from gefitinib-resistant NCI-H1299 cells caused enhanced sensitization to the inhibitors. Expression of TM4SF5 and IGF1R in the drug-sensitive cells promoted signaling activities of extracellular signal-regulated kinases (ERKs), protein kinase B (Akt), and S6 kinase (S6K), and resulted in a higher residual EGFR activity, even after EGFR kinase inhibitor treatment. Complex formation between TM4SF5 and IGF1R was observed, and also included EGFR, dependent on TM4SF5 expression. The TM4SF5-mediated drug resistance was further confirmed in an aqueous 3D spheroid system or upon being embedded in 3D extracellular matrix (ECM)-surrounded gel systems. Collectively, these data suggest that anti-TM4SF5 reagents may be combined with the EGFR kinase inhibitors to enhance the efficacy of chemotherapies against NSCLC. Copyright © 2015 Elsevier

Terahertz Magnon-Polaritons in TmFeO3.

PubMed

Grishunin, Kirill; Huisman, Thomas; Li, Guanqiao; Mishina, Elena; Rasing, Theo; Kimel, Alexey V; Zhang, Kailing; Jin, Zuanming; Cao, Shixun; Ren, Wei; Ma, Guo-Hong; Mikhaylovskiy, Rostislav V

2018-04-18

Magnon-polaritons are shown to play a dominant role in the propagation of terahertz (THz) waves through TmFeO 3 orthoferrite, if the frequencies of the waves are in the vicinity of the quasi-antiferromagnetic spin resonance mode. Both time-domain THz transmission and emission spectroscopies reveal clear beatings between two modes with frequencies slightly above and slightly below this resonance, respectively. Rigorous modeling of the interaction between the spins of TmFeO 3 and the THz light shows that the frequencies correspond to the upper and lower magnon-polariton branches. Our findings reveal the previously ignored importance of propagation effects and polaritons in such heavily debated areas as THz magnonics and THz spectroscopy of electromagnons. It also shows that future progress in these areas calls for an interdisciplinary approach at the interface between magnetism and photonics.

Joint NASA Ames/Langley Experimental Evaluation of Integrated Air/Ground Operations for En Route Free Maneuvering

NASA Technical Reports Server (NTRS)

Barhydt, Richard; Kopardekar, Parimal; Battiste, Vernol; Doble, Nathan; Johnson, Walter; Lee, Paul; Prevot, Thomas; Smith, Nancy

2005-01-01

In order to meet the anticipated future demand for air travel, the National Aeronautics and Space Administration (NASA) is investigating a new concept of operations known as Distributed Air-Ground Traffic Management (DAG-TM). Under the En Route Free Maneuvering component of DAG-TM, appropriately equipped autonomous aircraft self separate from other autonomous aircraft and from managed aircraft that continue to fly under today s Instrument Flight Rules (IFR). Controllers provide separation services between IFR aircraft and assign traffic flow management constraints to all aircraft. To address concept feasibility issues pertaining to integrated air/ground operations at various traffic levels, NASA Ames and Langley Research Centers conducted a joint human-in-the-loop experiment. Professional airline pilots and air traffic controllers flew a total of 16 scenarios under four conditions: mixed autonomous/managed operations at three traffic levels and a baseline all-managed condition at the lowest traffic level. These scenarios included en route flights and descents to a terminal area meter fix in airspace modeled after the Dallas Ft. Worth area. Pilots of autonomous aircraft met controller assigned meter fix constraints with high success. Separation violations by subject pilots did not appear to vary with traffic level and were mainly attributable to software errors and procedural lapses. Controller workload was lower for mixed flight conditions, even at higher traffic levels. Pilot workload was deemed acceptable under all conditions. Controllers raised several safety concerns, most of which pertained to the occurrence of near-term conflicts between autonomous and managed aircraft. These issues are being addressed through better compatibility between air and ground systems and refinements to air and ground procedures.

Origins of tmRNA: the missing link in the birth of protein synthesis?

PubMed

Macé, Kevin; Gillet, Reynald

2016-09-30

The RNA world hypothesis refers to the early period on earth in which RNA was central in assuring both genetic continuity and catalysis. The end of this era coincided with the development of the genetic code and protein synthesis, symbolized by the apparition of the first non-random messenger RNA (mRNA). Modern transfer-messenger RNA (tmRNA) is a unique hybrid molecule which has the properties of both mRNA and transfer RNA (tRNA). It acts as a key molecule during trans-translation, a major quality control pathway of modern bacterial protein synthesis. tmRNA shares many common characteristics with ancestral RNA. Here, we present a model in which proto-tmRNAs were the first molecules on earth to support non-random protein synthesis, explaining the emergence of early genetic code. In this way, proto-tmRNA could be the missing link between the first mRNA and tRNA molecules and modern ribosome-mediated protein synthesis. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

The Snow Data System at NASA JPL

NASA Astrophysics Data System (ADS)

Laidlaw, R.; Painter, T. H.; Mattmann, C. A.; Ramirez, P.; Bormann, K.; Brodzik, M. J.; Burgess, A. B.; Rittger, K.; Goodale, C. E.; Joyce, M.; McGibbney, L. J.; Zimdars, P.

2014-12-01

NASA JPL's Snow Data System has a data-processing pipeline powered by Apache OODT, an open source software tool. The pipeline has been running for several years and has successfully generated a significant amount of cryosphere data, including MODIS-based products such as MODSCAG, MODDRFS and MODICE, with historical and near-real time windows and covering regions such as the Artic, Western US, Alaska, Central Europe, Asia, South America, Australia and New Zealand. The team continues to improve the pipeline, using monitoring tools such as Ganglia to give an overview of operations, and improving fault-tolerance with automated recovery scripts. Several alternative adaptations of the Snow Covered Area and Grain size (SCAG) algorithm are being investigated. These include using VIIRS and Landsat TM/ETM+ satellite data as inputs. Parallel computing techniques are being considered for core SCAG processing, such as using the PyCUDA Python API to utilize multi-core GPU architectures. An experimental version of MODSCAG is also being developed for the Google Earth Engine platform, a cloud-based service.

Synthesis and structural characterization of transition metal doped MgO: Mg0.95Mn0.01TM0.04O (TM = Co, Ni, Cu)

NASA Astrophysics Data System (ADS)

Islam, Ishtihadah; Khandy, Shakeel Ahmad; Hafiz, Aurangzeb Khurram

2018-05-01

In the present work, preparation and characterization of transition metal doped MgO: Zn0.94Mn0.01TM0.05O (TM = Co, Ni and Cu) nano-particles have been reported. Transition metal doped samples of MgO were synthesized by Sol gel auto combustion method. Structural characterisation from XRD and SEM show the formation of single-phase primary particles, nearly of spherical shaped nano-crystallites. The crystallite size was found to be 78.2, 67.02, 78.11 and 64 nm for pure, Co, Cu and Ni doped MgMnO nano-particles, respectively. Hence, the average crystallite size increases monotonously from Co to Cu doping.

Tetraspanin TM4SF5 mediates loss of contact inhibition through epithelial-mesenchymal transition in human hepatocarcinoma

PubMed Central

Lee, Sin-Ae; Lee, Sung-Yul; Cho, Ik-Hyun; Oh, Min-A; Kang, Eun-Sil; Kim, Yong-Bae; Seo, Woo Duck; Choi, Suyong; Nam, Ju-Ock; Tamamori-Adachi, Mimi; Kitajima, Shigetaka; Ye, Sang-Kyu; Kim, Semi; Hwang, Yoon-Jin; Kim, In-San; Park, Ki Hun; Lee, Jung Weon

2008-01-01

The growth of normal cells is arrested when they come in contact with each other, a process known as contact inhibition. Contact inhibition is lost during tumorigenesis, resulting in uncontrolled cell growth. Here, we investigated the role of the tetraspanin transmembrane 4 superfamily member 5 (TM4SF5) in contact inhibition and tumorigenesis. We found that TM4SF5 was overexpressed in human hepatocarcinoma tissue. TM4SF5 expression in clinical samples and in human hepatocellular carcinoma cell lines correlated with enhanced p27Kip1 expression and cytosolic stabilization as well as morphological elongation mediated by RhoA inactivation. These TM4SF5-mediated effects resulted in epithelial-mesenchymal transition (EMT) via loss of E-cadherin expression. The consequence of this was aberrant cell growth, as assessed by S-phase transition in confluent conditions, anchorage-independent growth, and tumor formation in nude mice. The TM4SF5-mediated effects were abolished by suppressing the expression of either TM4SF5 or cytosolic p27Kip1, as well as by reconstituting the expression of E-cadherin. Our observations have revealed a role for TM4SF5 in causing uncontrolled growth of human hepatocarcinoma cells through EMT. PMID:18357344

TM-30 Guidance

DOE Office of Scientific and Technical Information (OSTI.GOV)

Royer, Michael P.

Minimum color quality standards are necessary, because the light sources most efficient at producing lumens are impractical for use in architectural lighting due to poor color rendition. Thus, accurate measures of color rendition and accompanying performance criteria are essential for helping technology developers and users balance tradeoffs between energy efficiency and lighting quality. Setting higher color-rendition criteria while maintaining use of CRI (e.g., CRI ≥ 90) may filter out some unacceptable light sources, but also filters out many highly desirable light sources and requires a greater tradeoff with energy efficiency. In contrast, specifying color rendition using TM-30 Rf, Rg, andmore » Rcs,h1 has been shown to be effective for differentiating desirable sources while maintaining flexibility for technology development and energy efficiency.« less

The SCERTS[TM] Model: A Comprehensive Educational Approach for Children with Autism Spectrum Disorders

ERIC Educational Resources Information Center

Prizant, Barry M.; Wetherby, Amy M.; Rubin, Emily; Laurent, Amy C.; Rydell, Patrick J.

2005-01-01

A groundbreaking synthesis of developmental, relationship-based, and skill-based approaches, The SCERTS[TM] Model provides a framework for improving communication and social-emotional abilities in individuals with autism spectrum disorders (ASD) and their families. Developed by internationally recognized experts, SCERTS[TM] supports developmental…

NASA Update

NASA Image and Video Library

2010-04-08

"NASA Update" program with NASA Administrator Charles Bolden, NASA Deputy Administrator Lori Garver and NASA Acting Asistant Administrator for Public Affairs Bob Jacobs as moderator, NASA Headquarters, Thursday, April 8, 2010 in Washington. Photo Credit: (NASA/Bill Ingalls)

ATE-TM mode splitter on lithium niobate using Ti, Ni, and MgO diffusions

NASA Astrophysics Data System (ADS)

Wei, Pei-Kuen; Wang, Way-Seen

1994-02-01

A new TE-TM mode splitter with an asymmetric Y-junction structure fabricated by diffusing different materials into y-cut lithium niobate is presented. Randomly polarized light launched into a titanium indiffused waveguide is split into TE and TM modes by two different single-polarization waveguides. The ordinary-polarized waveguide is made by nickel indiffusion and the extraordinary-polarized waveguide by magnesium-oxide induced lithium outdiffusion. The measured extinction ratios are greater than 20 dB for both TE and TM modes. The devices operate over a wide wavelength range and have a large fabrication tolerance.

Does LibQUAL+[TM] Account for Student Loyalty to a University College Library?

ERIC Educational Resources Information Center

Helgesen, Oyvind; Nesset, Erik

2011-01-01

Purpose: The purpose of this paper is to find out whether LibQUAL+[TM]can account for student loyalty to the library of an institution of higher education. LibQUAL+[TM] is a marketing tool that is used to measure perceived service quality of libraries, and the present analysis aims at validating this service quality instrument within a more…

Tm3+-doped lead silicate glass sensitized by Er3+ for efficient 2 μm mid-infrared laser material

NASA Astrophysics Data System (ADS)

Zhang, Junjie; Wang, Ning; Guo, Yanyan; Cai, Muzhi; Tian, Ying; Huang, Feifei; Xu, Shiqing

2018-06-01

Er3+/Tm3+ co-doped lead silicate glasses with low phonon (953 cm-1) and good thermal stability were synthesized. The 2 μm mid-infrared emission resulting from the 3F4 → 3H6 transition of Tm3+ sensitized by Er3+ has been observed by 808 nm LD pumping. The optimal luminescence intensity was obtained in the sample with 1Tm2O3/2.5Er2O3 co-doped. Moreover, the energy transfer mechanism from Er3+ to Tm3+ ion was analyzed. Absorption and emission cross section have been calculated. The calculated maximum emission cross section of Tm3+ is 2.689 × 10-21 cm2 at 1863 nm. Microparameters of energy transfer between Er3+ and Tm3+ ions have also been analyzed. These results ensure that the prepared Er3+/Tm3+ co-doped lead silicate glasses have excellent spectroscopic properties in mid-infrared region and provide a beneficial guide for mid-infrared laser material.

Integration of Landsat TM and SPOT HRG Images for Vegetation Change Detection in the Brazilian Amazon

PubMed Central

Lu, Dengsheng; Batistella, Mateus; Moran, Emilio

2009-01-01

Traditional change detection approaches have been proven to be difficult in detecting vegetation changes in the moist tropical regions with multitemporal images. This paper explores the integration of Landsat Thematic Mapper (TM) and SPOT High Resolution Geometric (HRG) instrument data for vegetation change detection in the Brazilian Amazon. A principal component analysis was used to integrate TM and HRG panchromatic data. Vegetation change/non-change was detected with the image differencing approach based on the TM and HRG fused image and the corresponding TM image. A rule-based approach was used to classify the TM and HRG multispectral images into thematic maps with three coarse land-cover classes: forest, non-forest vegetation, and non-vegetation lands. A hybrid approach combining image differencing and post-classification comparison was used to detect vegetation change trajectories. This research indicates promising vegetation change techniques, especially for vegetation gain and loss, even if very limited reference data are available. PMID:19789721

LANDSAT-4 TM image data quality analysis for energy-related applications

NASA Technical Reports Server (NTRS)

Wukelic, G. E.; Foote, H. P.

1983-01-01

LANDSAT-4 Thematic Mapper (TM) data performance and utility characteristics from an energy research and technology perspective is evaluated. The program focuses on evaluating applicational implications of using such data, in combination with other digital data, for current and future energy research and technology activities. Prime interest is in using TM data for siting, developing and operating federal energy facilities. Secondary interests involve the use of such data for resource exploration, environmental monitoring and basic scientific initiatives such as in support of the Continental Scientific Drilling Program.

[Expression optimization and characterization of Tenebrio molitor antimicrobiol peptides TmAMP1m in Escherichia coli].

PubMed

Alimu, Reyihanguli; Mao, Xinfang; Liu, Zhongyuan

2013-06-01

To improve the expression level of tmAMP1m gene from Tenebrio molitor in Escherichia coli, we studied the effects of expression level and activity of the fusion protein HIS-TmAMP1m by conditions, such as culture temperature, inducing time and the final concentration of inductor Isopropyl beta-D-thiogalactopyranoside (IPTG). We analyzed the optimum expression conditions by Tricine-SDS-PAGE electrophoresis, meanwhile, detected its antibacterial activity by using agarose cavity diffusion method. The results suggest that when inducing the recombinant plasmid with a final IPTG concentration of 0.1 mmol/L at 37 degrees C for 4 h, there was the highest expression level of fusion protein HIS-TmAMP1m in Escherichia coli. Under these conditions, the expression of fusion protein accounted for 40% of the total cell lysate with the best antibacterial activity. We purified the fusion protein HIS-TmAMPlm with nickel-nitrilotriacetic acid (Ni-NTA) metal-affinity chromatography matrices. Western blotting analysis indicates that the His monoclonal antibody could be specifically bound to fusion protein HIS-TmAMPlm. After expression by inducing, the fusion protein could inhibit the growth of host cell transformed by pET30a-tmAMP1m. The fusion protein HIS-TmAMP1m had better stability and remained higher antibacterial activities when incubated at 100 degrees C for 10 h, repeated freeze thawing at -20 degrees C, dissolved in strong acid and alkali, or treated by organic solvents and protease. Moreover, the minimum inhibitory concentration results demonstrated that the fusion protein HIS-TmAMP1m has a good antibacterial activity against Staphylococcus aureus, Staphylococcus sp., Corynebacterium glutamicum, Bacillus thuringiensis, Corynebacterium sp. This study laid the foundation to promote the application of insect antimicrobial peptides and further research.

Results of NASA's First Autonomous Formation Flying Experiment: Earth Observing-1 (EO-1)

NASA Technical Reports Server (NTRS)

Folta, David C.; Hawkins, Albin; Bauer, Frank H. (Technical Monitor)

2001-01-01

NASA's first autonomous formation flying mission completed its primary goal of demonstrating an advanced technology called enhanced formation flying. To enable this technology, the Guidance, Navigation, and Control center at the Goddard Space Flight Center (GSFC) implemented a universal 3-axis formation flying algorithm in an autonomous executive flight code onboard the New Millennium Program's (NMP) Earth Observing-1 (EO-1) spacecraft. This paper describes the mathematical background of the autonomous formation flying algorithm and the onboard flight design and presents the validation results of this unique system. Results from functionality assessment through fully autonomous maneuver control are presented as comparisons between the onboard EO-1 operational autonomous control system called AutoCon(tm), its ground-based predecessor, and a standalone algorithm.

Construction of pTM series plasmids for gene expression in Brucella species.

PubMed

Tian, Mingxing; Qu, Jing; Bao, Yanqing; Gao, Jianpeng; Liu, Jiameng; Wang, Shaohui; Sun, Yingjie; Ding, Chan; Yu, Shengqing

2016-04-01

Brucellosis, the most common widespread zoonotic disease, is caused by Brucella spp., which are facultative, intracellular, Gram-negative bacteria. With the development of molecular biology techniques, more and more virulence-associated factors have been identified in Brucella spp. A suitable plasmid system is an important tool to study virulence genes in Brucella. In this study, we constructed three constitutive replication plasmids (pTM1-Cm, pTM2-Amp, and pTM3-Km) using the replication origin (rep) region derived from the pBBR1-MCS vector. Also, a DNA fragment containing multiple cloning sites (MCSs) and a terminator sequence derived from the pCold vector were produced for complementation of the deleted genes. Besides pGH-6×His, a plasmid containing the groE promoter of Brucella spp. was constructed to express exogenous proteins in Brucella with high efficiency. Furthermore, we constructed the inducible expression plasmid pZT-6×His, containing the tetracycline-inducible promoter pzt1, which can induce expression by the addition of tetracycline in the Brucella culture medium. The constructed pTM series plasmids will play an important role in the functional investigation of Brucella spp. Copyright © 2016 Elsevier B.V. All rights reserved.

Optical decoherence studies of Tm3 +:Y3Ga5O12

NASA Astrophysics Data System (ADS)

Thiel, C. W.; Sinclair, N.; Tittel, W.; Cone, R. L.

2014-12-01

Decoherence of the 795 nm 3H6 to 3H4 transition in 1 %Tm3 +:Y3Ga5O12 (Tm:YGG) is studied at temperatures as low as 1.2 K. The temperature, magnetic field, frequency, and time scale (spectral diffusion) dependence of the optical coherence lifetime is measured. Our results show that the coherence lifetime is impacted less by spectral diffusion than other known thulium-doped materials. Photon echo excitation and spectral hole burning methods reveal uniform decoherence properties and the possibility to produce full transparency for persistent spectral holes across the entire 56 GHz inhomogeneous bandwidth of the optical transition. Temperature-dependent decoherence is well described by elastic Raman scattering of phonons with an additional weaker component that may arise from a low density of glass-like dynamic disorder modes (two-level systems). Analysis of the observed behavior suggests that an optical coherence lifetime approaching 1 ms may be possible in this system at temperatures below 1 K for crystals grown with optimized properties. Overall, we find that Tm:YGG has superior decoherence properties compared to other Tm-doped crystals and is a promising candidate for applications that rely on long coherence lifetimes, such as optical quantum memories and photonic signal processing.

Evaluation of Montanide TM ISA 71 VG adjuvant during profilin vaccination against experimental coccidiosis

USDA-ARS?s Scientific Manuscript database

Chickens were immunized subcutaneously with an Eimeria recombinant profilin protein plus MontanideTM ISA 70 VG (ISA 70) or MontanideTM ISA 71 VG (ISA 71) water-in-oil adjuvants, or with profilin alone, and comparative RNA microarray analyses were performed to ascertain global transcriptomic changes ...

Pulsed Tm:YAG laser ablation of knee joint tissues

NASA Astrophysics Data System (ADS)

Shi, Wei-Qiang; Vari, Sandor G.; Duffy, J. T.; Miller, J. M.; Weiss, Andrew B.; Fishbein, Michael C.; Grundfest, Warren S.

1992-06-01

We investigated the effect of a free-running 2.01 micron pulsed Tm:YAG laser on bovine knee joint tissues. Ablation rates of fresh fibrocartilage, hyaline cartilage, and bone were measured in saline as a function of laser fluence (160 - 640 J/cm2) and fiber core size (400 and 600 microns). All tissues could be effectively ablated and the ablation rate increased linearly with the increasing fluence. Use of fibers of different core sizes, while maintaining constant energy fluence, did not result in significant difference in ablation rate. Histology analyses of the ablated tissue samples reveal average Tm:YAG radiation induced thermal damage (denatunalization) zones ranging between 130 and 540 microns, depending on the laser parameters and the tissue type.

Anisotropic magnetic properties of the triangular plane lattice material TmMgGaO 4

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cevallos, F. Alex; Stolze, Karoline; Kong, Tai

Here, the crystal growth, structure, and basic magnetic properties of TmMgGaO 4 are reported. The Tm ions are located in a planar triangular lattice consisting of distorted TmO6 octahedra, while the Mg and Ga atoms randomly occupy intermediary bilayers of M-O triangular bipyramids. The Tm ions are positionally disordered. The material displays an antiferromagnetic Curie Weiss theta of ~ -20 -25 K, with no clear ordering visible in the magnetic susceptibility down to 1.8 K; the structure and magnetic properties suggest that ordering of the magnetic moments is frustrated by both structural disorder and the triangular magnetic motif. Single crystalmore » magnetization measurements indicate that the magnetic properties are highly anisotropic, with large moments measured perpendicular to the triangular planes. At 2 K, a broad step-like feature is seen in the field-dependent magnetization perpendicular to the plane on applied field near 2 Tesla.« less

Ultra-wideband all-fiber tunable Tm/Ho-co-doped laser at 2 μm.

PubMed

Xue, Guanghui; Zhang, Bin; Yin, Ke; Yang, Weiqiang; Hou, Jing

2014-10-20

We demonstrate an all-fiber tunable Tm/Ho-codoped laser operating in the 2 μm wavelength region. The wavelength tuning range of the Tm/Ho-codoped fiber laser (THFL) with 1-m length of Tm/Ho-codoped fiber (THDF) was from 1727 nm to 2030 nm. Efficient short wavelength operation and ultra-wide wavelength tuning range of 303 nm were both achieved. To the best of our knowledge, this is the broadest tuning range that has been reported for an all-fiber rare-earth-doped laser to date. By increasing the THDF length to 2 m, the obtainable wavelength of the THFL was further red-shifted to the range from 1768 nm to 2071 nm. The output power of the THFL was scaled up from 1810 nm to 2010 nm by using a stage of Tm/Ho-codoped fiber amplifier (THFA), which exhibited the maximum slope efficiency of 42.6% with output power of 408 mW at 1910 nm.

Anisotropic magnetic properties of the triangular plane lattice material TmMgGaO 4

DOE PAGES

Cevallos, F. Alex; Stolze, Karoline; Kong, Tai; ...

2018-04-30

Here, the crystal growth, structure, and basic magnetic properties of TmMgGaO 4 are reported. The Tm ions are located in a planar triangular lattice consisting of distorted TmO6 octahedra, while the Mg and Ga atoms randomly occupy intermediary bilayers of M-O triangular bipyramids. The Tm ions are positionally disordered. The material displays an antiferromagnetic Curie Weiss theta of ~ -20 -25 K, with no clear ordering visible in the magnetic susceptibility down to 1.8 K; the structure and magnetic properties suggest that ordering of the magnetic moments is frustrated by both structural disorder and the triangular magnetic motif. Single crystalmore » magnetization measurements indicate that the magnetic properties are highly anisotropic, with large moments measured perpendicular to the triangular planes. At 2 K, a broad step-like feature is seen in the field-dependent magnetization perpendicular to the plane on applied field near 2 Tesla.« less

NASA #801 and NASA 7 on ramp

NASA Technical Reports Server (NTRS)

1997-01-01

NASA N801NA and NASA 7 together on the NASA Dryden ramp. The Beechcraft Beech 200 Super KingAir aircraft N7NA, known as NASA 7, has been a support aircraft for many years, flying 'shuttle' missions to Ames Research Center. It once flew from the Jet Propulsion Laboratory and back each day but now (2001) flies between the Dryden Flight Research Center and Ames. A second Beechcraft Beech 200 Super King Air, N701NA, redesignated N801NA, transferred to Dryden on 3 Oct. 1997 and is used for research missions but substitutes for NASA 7 on shuttle missions when NASA 7 is not available.

Development of a Compact, Pulsed, 2-Micron, Coherent-Detection, Doppler Wind Lidar Transceiver; and Plans for Flights on NASA's DC-8 and WB-57 Aircraft

NASA Technical Reports Server (NTRS)

Kavaya, Michael J.; Singh, Upendra N.; Koch, Grady J.; Yu, Jirong; Trieu, Bo C.; Petros, Mulugeta; Petzar, Paul J.

2009-01-01

We present results of a recently completed effort to design, fabricate, and demonstrate a compact lidar transceiver for coherent-detection lidar profiling of winds. The novel high-energy, 2-micron, Ho:Tm:LuLiF laser technology developed at NASA Langley was employed to permit study of the laser technology currently envisioned by NASA for global coherent Doppler lidar measurement of winds in the future. The 250 mJ, 10 Hz compact transceiver was also designed for future aircraft flight. Ground-based wind profiles made with this transceiver will be presented. NASA Langley is currently funded to build complete Doppler lidar systems using this transceiver for the DC-8 and WB-57 aircraft. The WB-57 flights will present a more severe environment and will require autonomous operation of the lidar system. The DC-8 lidar system is a likely component of future NASA hurricane research. It will include real-time data processing and display, as well as full data archiving. We will attempt to co-fly on both aircraft with a direct-detection Doppler wind lidar system being prepared by NASA Goddard Space Flight Center.

BOREAS RSS-8 Snow Maps Derived from Landsat TM Imagery

NASA Technical Reports Server (NTRS)

Hall, Dorothy; Chang, Alfred T. C.; Foster, James L.; Chien, Janeet Y. L.; Hall, Forrest G. (Editor); Nickeson, Jaime (Editor); Smith, David E. (Technical Monitor)

2000-01-01

The Boreal Ecosystem-Atmosphere Study (BOREAS) Remote Sensing Science (RSS)-8 team utilized Landsat Thematic Mapper (TM) images to perform mapping of snow extent over the Southern Study Area (SSA). This data set consists of two Landsat TM images that were used to determine the snow-covered pixels over the BOREAS SSA on 18 Jan 1993 and on 06 Feb 1994. The data are stored in binary image format files. The RSS-08 snow map data are available from the Earth Observing System Data and Information System (EOSDIS) Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC). The data files are available on a CD-ROM (see document number 20010000884).

Wigner time delay in photodetachment of Tm-and in photoionization of Yb: A comparative study

NASA Astrophysics Data System (ADS)

Saha, Soumyajit; Jose, Jobin; Deshmukh, Pranawa; Dolmatov, Valeriy; Kheifets, Anatoli; Manson, Steven

2017-04-01

Preliminary studies of Wigner time delay in photodetachment spectra of negative ions have been reported. Photodetachment time delay for some dipole channels of Tm- and of Cl- were calculated using relativistic random phase approximation (RRPA). Comparisons between photodetachment time delay of Cl- and photoionization time delay of Ar were made. We investigate the photodetachment time delay for all three relativistically split nd -> ɛ f channels of Tm- and for nd -> ɛ f channels of Yb (isoelectronic to Tm-) using RRPA. We study the effect of the shape resonance, brought about by the centrifugal barrier potential, on photodetachment time delay. A negative ion is a good laboratory for studying the effects of shape resonances on time delay since the phase is unaffected by the Coulomb component. Wigner time delay in photodetachment of Tm- and in photoionization of Yb: A comparative study.

Fusion of AIRSAR and TM Data for Parameter Classification and Estimation in Dense and Hilly Forests

NASA Technical Reports Server (NTRS)

Moghaddam, Mahta; Dungan, J. L.; Coughlan, J. C.

2000-01-01

ecologists for forest process modeling. These parameters include total biomass, leaf biomass, LAI, and tree height. The remote sensing data from radar and TM are used to formulate a multivariate analysis problem given the ground measurements of the parameters. Each class of each parameter is defined by a probability density function (pdf), the spread of which defines the range of that class. High classification accuracy results from situations in which little overlap occurs between pdfs. Classification results provide the basis for the future work of class-specific parameter estimation using radar and optical data. This work was performed in part by the Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, and in part by the NASA Ames Research Center, Moffett Field, CA, both under contract from the National Aeronautics and Space Administration.

The statistics of identifying differentially expressed genes in Expresso and TM4: a comparison

PubMed Central

Sioson, Allan A; Mane, Shrinivasrao P; Li, Pinghua; Sha, Wei; Heath, Lenwood S; Bohnert, Hans J; Grene, Ruth

2006-01-01

Background Analysis of DNA microarray data takes as input spot intensity measurements from scanner software and returns differential expression of genes between two conditions, together with a statistical significance assessment. This process typically consists of two steps: data normalization and identification of differentially expressed genes through statistical analysis. The Expresso microarray experiment management system implements these steps with a two-stage, log-linear ANOVA mixed model technique, tailored to individual experimental designs. The complement of tools in TM4, on the other hand, is based on a number of preset design choices that limit its flexibility. In the TM4 microarray analysis suite, normalization, filter, and analysis methods form an analysis pipeline. TM4 computes integrated intensity values (IIV) from the average intensities and spot pixel counts returned by the scanner software as input to its normalization steps. By contrast, Expresso can use either IIV data or median intensity values (MIV). Here, we compare Expresso and TM4 analysis of two experiments and assess the results against qRT-PCR data. Results The Expresso analysis using MIV data consistently identifies more genes as differentially expressed, when compared to Expresso analysis with IIV data. The typical TM4 normalization and filtering pipeline corrects systematic intensity-specific bias on a per microarray basis. Subsequent statistical analysis with Expresso or a TM4 t-test can effectively identify differentially expressed genes. The best agreement with qRT-PCR data is obtained through the use of Expresso analysis and MIV data. Conclusion The results of this research are of practical value to biologists who analyze microarray data sets. The TM4 normalization and filtering pipeline corrects microarray-specific systematic bias and complements the normalization stage in Expresso analysis. The results of Expresso using MIV data have the best agreement with qRT-PCR results. In

Transmembrane 4 L Six Family Member 5 (TM4SF5)-Mediated Epithelial-Mesenchymal Transition in Liver Diseases.

PubMed

Lee, Jung Weon

2015-01-01

The membrane protein TM4SF5, a member of the transmembrane 4L six family, forms a tetraspanin-enriched microdomain (TEM) on the cell surface, where many different membrane proteins and receptors form a massive protein-protein complex to regulate cellular functions including transdifferentiation, migration, and invasion. We recently reported that TM4SF5 causes epithelial-mesenchymal transition (EMT), eventually contributing to aberrant multilayer cellular growth, drug resistance, enhanced migration, invasion, its circulation in the blood, tumor initiation for successful metastasis, and muscle development in zebrafish. In this review, I summarize the information on the role of TM4SF5 in EMT-related functions at TM4SF5-enriched microdomain (T5EM) on cell surface, where proteins such as TM4SF5, CD151, CD44, integrins, and epidermal growth factor receptor (EGFR) can form numerous protein complexes. TM4SF5-mediated EMT contributes to diverse cellular functions, leading to fibrotic phenotypes and initiating and maintaining tumors in primary and/or metastatic regions, in addition to its role in muscle development in zebrafish. Anti-TM4SF5 strategies for addressing the protein networks can lead to regulation of the fibrotic, tumorigenic, and tumor-maintaining functions of TM4SF5-positive hepatic cells. This review is for us to (re)consider the antifibrotic or antitumorigenic (i.e., anti-EMT-related diseases) strategies of dealing with protein networks that would be involved in cross-talks to regulate various cellular functions during TM4SF5-dependent progression from fibrotic to cancerous hepatic cells. Copyright © 2015 Elsevier Inc. All rights reserved.

Montessori(TM) Math by Colors [CD Rom.

ERIC Educational Resources Information Center

1995

Montessori(TM) Learning Software programs are purportedly built upon the core concept of the Montessori philosophy, that a major path to intellectual development is through a child's hands and senses. Math by Colors, recommended for ages 4 to 8, encourages hands-on discovery by allowing the child to choose the right color from the assembled paint…

Supporting Moral Development: The Virtues Project[TM

ERIC Educational Resources Information Center

de Moor, Gerrit

2011-01-01

The Virtues Project[TM] was founded in Canada in 1991 by Linda Kavelin Popov, Dan Popov, and John Kavelin who were concerned about the level of violence among families and youth. In studying sacred traditions and cultures around the world, they identified a set of common virtues. These were used to develop a pedagogical model that has applications…

NASA Update

NASA Image and Video Library

2011-02-15

NASA Administrator Charles F. Bolden Jr., answers questions during a NASA Update on, Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and NASA Deputy Administrator Lori Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

An Efficient End-Pumped Ho:Tm:YLF Disk Amplifier

NASA Technical Reports Server (NTRS)

Yu, Ji-Rong; Petros, Mulugeta; Singh, Upendra N.; Barnes, Norman P.

2000-01-01

An efficient diode-pumped, room temperature Ho:Tm:YLF disk amplifier was realized by end-pump configuration. Compared to side pump configuration, about a factor three improvement in system efficiency has been demonstrated.

75 FR 5071 - Mississippi L&D 21, LLC, Mississippi River No. 21 Hydropower Company Lock + TM

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-01

... Lock + \\TM\\ Hydro Friends Fund XXXII, LLC; Notice of Preliminary Permit Applications Accepted for..., Lock + TM Hydro Friends Fund XXXII, LLC (Lock + Hydro) filed an application for a preliminary permit...

Shedding light on microbial dark matter: a TM6 bacterium as natural endosymbiont of a free-living amoeba.

PubMed

Delafont, Vincent; Samba-Louaka, Ascel; Bouchon, Didier; Moulin, Laurent; Héchard, Yann

2015-12-01

The TM6 phylum belongs to the so-called microbial dark matter that gathers uncultivated bacteria detected only via DNA sequencing. Recently, the genome sequence of a TM6 bacterium (TM6SC1) has led to suggest that this bacterium would adopt an endosymbiotic life. In the present paper, free-living amoebae bearing a TM6 strain were isolated from a water network. The amoebae were identified as Vermamoeba vermiformis and the presence of a TM6 strain was detected by polymerase chain reaction and microscopy. The partial sequence of its 16S rRNA gene showed this strain to be closely related to the sequenced TM6SC1 strain. These bacteria displayed a pyriform shape and were found within V. vermiformis. Therefore, these bacteria were named Vermiphilus pyriformis. Interactions studies showed that V. pyriformis was highly infectious and that its relation with V. vermiformis was specific and highly stable. Finally, it was found that V. pyriformis inhibited the encystment of V. vermiformis. Overall, this study describes for the first time an endosymbiotic relationship between a TM6 bacterium and a free-living amoeba in the environment. It suggests that other bacteria of the TM6 phylum might also be endosymbiotic bacteria and may be found in other free-living amoebae or other organisms. © 2015 Society for Applied Microbiology and John Wiley & Sons Ltd.

66.7-keV γ -line intensity of 171Tm determined via neutron activation

NASA Astrophysics Data System (ADS)

Weigand, M.; Heftrich, T.; Düllmann, Ch. E.; Eberhardt, K.; Fiebiger, S.; Glorius, J.; Göbel, K.; Haas, R.; Langer, C.; Lohse, S.; Reifarth, R.; Renisch, D.; Wolf, C.

2018-03-01

Background: About 50% of the heavy elements are produced in stars during the slow neutron capture process. The analysis of branching points allows to set constraints on the temperature and the neutron density in the interior of stars. The temperature dependence of the branch point 171Tm is weak. Hence, the 171Tm neutron capture cross section can be used to constrain the neutron density during the main component of the s process in thermally pulsing asymptotic giant branch stars. Purpose: In order to perform neutron capture experiments on 171Tm, sample material has to be produced and characterized. The characterization is done by γ spectroscopy, relying on the intensities of the involved γ lines. Only the 66.7-keV γ line can be observed whose intensity was uncertain so far. Method: An enriched 170Er sample was activated with thermal neutrons at the TRIGA (Training, Research, Isotopes, General Atomics) research reactor at the Johannes Gutenberg-Universität Mainz. The activation resulted in an easily quantifiable number of 171Er nuclei that subsequently decayed to 171Tm. Result: The intensity of the 66.7-keV γ line of the 171Tm decay was measured to Iγ=(0.144 ±0.010 )% . Conclusions: Our result is in good agreement with the value found in the literature.

Diode-Pumped Thulium (Tm)/Holmium (Ho) Composite Fiber 2.1-Micrometers Laser

DTIC Science & Technology

2015-09-01

composite fiber laser of holmium-core and thulium-doped cladding . The composite fiber was optically pumped by an 803-nm fiber coupled diode source and was...4 odd and 5 even modes were exclusive to the core and first cladding . As the Tm laser modes are excluded from lasing in the second (undoped...of the Tm-doped clad /Ho-doped core fiber laser . In particular, calculations of the model overlap of the cladding modes with the core have been

Development of a data acquisition system using a RISC/UNIX TM workstation

NASA Astrophysics Data System (ADS)

Takeuchi, Y.; Tanimori, T.; Yasu, Y.

1993-05-01

We have developed a compact data acquisition system on RISC/UNIX workstations. A SUN TM SPARCstation TM IPC was used, in which an extension bus "SBus TM" was linked to a VMEbus. The transfer rate achieved was better than 7 Mbyte/s between the VMEbus and the SUN. A device driver for CAMAC was developed in order to realize an interruptive feature in UNIX. In addition, list processing has been incorporated in order to keep the high priority of the data handling process in UNIX. The successful developments of both device driver and list processing have made it possible to realize the good real-time feature on the RISC/UNIX system. Based on this architecture, a portable and versatile data taking system has been developed, which consists of a graphical user interface, I/O handler, user analysis process, process manager and a CAMAC device driver.

Development of an Outreach Program for NASA: "NASA Ambassadors"

NASA Technical Reports Server (NTRS)

Lebo, George R.

1996-01-01

It is widely known that the average American citizen has either no idea or the wrong impression of what NASA is doing. The most common impression is that NASA's sole mission is to build and launch spacecraft and that the everyday experience of the common citizen would be impacted very little if NASA failed to exist altogether. Some feel that most of NASA's efforts are much too expensive and that the money would be better used on other efforts. Others feel that most of NASA's efforts either fail altogether or fail to meet their original objectives. Yet others feel that NASA is so mired in bureaucracy that it is no longer able to function. The goal of the NASA Ambassadors Program (NAP) is to educate the general populace as to what NASA's mission and goals actually are, to re-excite the "man on the street" with NASA's discoveries and technologies, and to convince him that NASA really does impact his everyday experience and that the economy of the U.S. is very dependent on NASA-type research. Each of the NASA centers currently run a speakers bureau through its Public Affairs Office (PAO). The speakers, NASA employees, are scheduled on an "as available" status and their travel is paid by NASA. However, there are only a limited number of them and their message may be regarded as being somewhat biased as they are paid by NASA. On the other hand, there are many members of NASA's summer programs which come from all areas of the country. Most of them not only believe that NASA's mission is important but are willing and able to articulate it to others. Furthermore, in the eyes of the public, they are probably more effective as ambassadors for NASA than are the NASA employees, as they do not derive their primary funding from it. Therefore it was decided to organize materials for them to use in presentations to general audiences in their home areas. Each person who accepted these materials was to be called a "NASA Ambassador".

Todd Moore d/b/a TM Construction Information Sheet

EPA Pesticide Factsheets

Todd Moore d/b/a TM Construction (the Company) is located in St. Louis, Missouri. The settlement involves renovation activities conducted at a residential property constructed prior to 1978, located in St. Louis, Missouri.

"Zones of Tolerance" in Perceptions of Library Service Quality: A LibQUAL+[TM] Study.

ERIC Educational Resources Information Center

Cook, Colleen; Heath, Fred M.; Thompson, Bruce

2003-01-01

One of the two major ways of interpreting LibQUAL+[TM] data involves placing perceived service quality ratings within "zones of tolerance" defined as the distances between minimally-acceptable and desired service quality levels. This study compared zones of tolerance on the 25 LibQUAL+[TM] items across undergraduate, graduate student and…

NASA Update

NASA Image and Video Library

2009-07-20

NASA Deputy Administrator Lori Garver, right, looks on as NASA Administrator Charles F. Bolden Jr. speaks during his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2009-07-20

NASA Deputy Administrator Lori Garver, second right on stage, speaks as NASA Administrator Charles F. Bolden Jr. looks on during a NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

Secondary Forest Age and Tropical Forest Biomass Estimation Using TM

NASA Technical Reports Server (NTRS)

Nelson, R. F.; Kimes, D. S.; Salas, W. A.; Routhier, M.

1999-01-01

The age of secondary forests in the Amazon will become more critical with respect to the estimation of biomass and carbon budgets as tropical forest conversion continues. Multitemporal Thematic Mapper data were used to develop land cover histories for a 33,000 Square kM area near Ariquemes, Rondonia over a 7 year period from 1989-1995. The age of the secondary forest, a surrogate for the amount of biomass (or carbon) stored above-ground, was found to be unimportant in terms of biomass budget error rates in a forested TM scene which had undergone a 20% conversion to nonforest/agricultural cover types. In such a situation, the 80% of the scene still covered by primary forest accounted for over 98% of the scene biomass. The difference between secondary forest biomass estimates developed with and without age information were inconsequential relative to the estimate of biomass for the entire scene. However, in futuristic scenarios where all of the primary forest has been converted to agriculture and secondary forest (55% and 42% respectively), the ability to age secondary forest becomes critical. Depending on biomass accumulation rate assumptions, scene biomass budget errors on the order of -10% to +30% are likely if the age of the secondary forests are not taken into account. Single-date TM imagery cannot be used to accurately age secondary forests into single-year classes. A neural network utilizing TM band 2 and three TM spectral-texture measures (bands 3 and 5) predicted secondary forest age over a range of 0-7 years with an RMSE of 1.59 years and an R(Squared) (sub actual vs predicted) = 0.37. A proposal is made, based on a literature review, to use satellite imagery to identify general secondary forest age groups which, within group, exhibit relatively constant biomass accumulation rates.

Mass balance investigation of alpine glaciers through LANDSAT TM data

NASA Technical Reports Server (NTRS)

Bayr, Klaus J.

1989-01-01

An analysis of LANDSAT Thematic Mapper (TM) data of the Pasterze Glacier and the Kleines Fleisskees in the Austrian Alps was undertaken and compared with meteorological data of nearby weather stations. Alpine or valley glaciers can be used to study regional and worldwide climate changes. Alpine glaciers respond relatively fast to a warming or cooling trend in temperature through an advance or a retreat of the terminus. In addition, the mass balance of the glacier is being affected. Last year two TM scenes of the Pasterze Glacier of Aug. 1984 and Aug. 1986 were used to study the difference in reflectance. This year, in addition to the scenes from last year, one MSS scene of Aug. 1976 and a TM scene from 1988 were examined for both the Pasterze Glacier and the Kleines Fleisskees. During the overpass of the LANDSAT on 6 Aug. 1988 ground truthing on the Pasterze Glacier was undertaken. The results indicate that there was considerable more reflectance in 1976 and 1984 than in 1986 and 1988. The climatological data of the weather stations Sonnblick and Rudolfshuette were examined and compared with the results found through the LANDSAT data. There were relations between the meteorological and LANDSAT data: the average temperature over the last 100 years showed an increase of .4 C, the snowfall was declining during the same time period but the overall precipitation did not reveal any significant change over the same period. With the use of an interactive image analysis computer, the LANDSAT scenes were studied. The terminus of the Pasterze Glacier retreated 348 m and the terminus of the Kleines Fleisskees 121 m since 1965. This approach using LANDSAT MSS and TM digital data in conjunction with meteorological data can be effectively used to monitor regional and worldwide climate changes.

Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells.

PubMed

Mody, Avani A; Wordinger, Robert J; Clark, Abbot F

2017-02-01

Increased expression of TGF-β2 in primary open-angle glaucoma (POAG) aqueous humor (AH) and trabecular meshwork (TM) causes deposition of extracellular matrix (ECM) in the TM and elevated IOP. Bone morphogenetic proteins (BMPs) regulate TGF-β2-induced ECM production. The underlying mechanism for BMP4 inhibition of TGF-β2-induced fibrosis remains undetermined. Bone morphogenic protein 4 induces inhibitor of DNA binding proteins (ID1, ID3), which suppress transcription factor activities to regulate gene expression. Our study will determine whether ID1and ID3 proteins are downstream targets of BMP4, which attenuates TGF-β2 induction of ECM proteins in TM cells. Primary human TM cells were treated with BMP4, and ID1 and ID3 mRNA, and protein expression was determined by quantitative PCR (Q-PCR) and Western immunoblotting. Intracellular ID1 and ID3 protein localization was studied by immunocytochemistry. Transformed human TM cells (GTM3 cells) were transfected with ID1 or ID3 expression vectors to determine their potential inhibitory effects on TGF-β2-induced fibronectin and plasminogen activator inhibitor-I (PAI-1) protein expression. Basal expression of ID1-3 was detected in primary human TM cells. Bone morphogenic protein 4 significantly induced early expression of ID1 and ID3 mRNA (P < 0.05) and protein in primary TM cells, and a BMP receptor inhibitor blocked this induction. Overexpression of ID1 and ID3 significantly inhibited TGF-β2-induced expression of fibronectin and PAI-1 in TM cells (P < 0.01). Bone morphogenic protein 4 induced ID1 and ID3 expression suppresses TGF-β2 profibrotic activity in human TM cells. In the future, targeting specific regulators may control the TGF-β2 profibrotic effects on the TM, leading to disease modifying IOP lowering therapies.

Culture-independent detection of 'TM7' bacteria in a streptomycin-resistant acidophilic nitrifying process

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kurogi, T.; Linh, N. T. T.; Kuroki, T.

2014-02-20

Nitrification in biological wastewater treatment processes has been believed for long time to take place under neutral conditions and is inhibited under acidic conditions. However, we previously constructed acidophilic nitrifying sequencing-batch reactors (ANSBRs) being capable of nitrification at < pH 4 and harboring bacteria of the candidate phylum 'TM7' as the major constituents of the microbial community. In light of the fact that the 16S rRNA of TM7 bacteria has a highly atypical base substitution possibly responsible for resistance to streptomycin at the ribosome level, this study was undertaken to construct streptomycin-resistant acidophilic nitrifying (SRAN) reactors and to demonstrate whethermore » TM7 bacteria are abundant in these reactors. The SRAN reactors were constructed by seeding with nitrifying sludge from an ANSBR and cultivating with ammonium-containing mineral medium (pH 4.0), to which streptomycin at a concentration of 10, 30 and 50 mg L{sup −1} was added. In all reactors, the pH varied between 2.7 and 4.0, and ammonium was completely converted to nitrate in every batch cycle. PCR-aided denaturing gradient gel electrophoresis (DGGE) targeting 16S rRNA genes revealed that some major clones assigned to TM7 bacteria and Gammaproteobacteria were constantly present during the overall period of operation. Fluorescence in situ hybridization (FISH) with specific oligonucleotide probes also showed that TM7 bacteria predominated in all SRAN reactors, accounting for 58% of the total bacterial population on average. Although the biological significance of the TM7 bacteria in the SRAN reactors are unknown, our results suggest that these bacteria are possibly streptomycin-resistant and play some important roles in the acidophilic nitrifying process.« less

A millimeter wave relativistic backward wave oscillator operating in TM{sub 03} mode with low guiding magnetic field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ye, Hu; Wu, Ping; Science and Technology on High Power Microwave Laboratory, Northwest Institute of Nuclear Technology, Xi'an Shaanxi 710024

2015-06-15

A V-band overmoded relativistic backward wave oscillator (RBWO) guided by low magnetic field and operating on a TM{sub 03} mode is presented to increase both the power handling capacity and the wave-beam interaction conversion efficiency. Trapezoidal slow wave structures (SWSs) with shallow corrugations and long periods are adopted to make the group velocity of TM{sub 03} mode at the intersection point close to zero. The coupling impedance and diffraction Q-factor of the RBWO increase, while the starting current decreases owing to the reduction of the group velocity of TM{sub 03} mode. In addition, the TM{sub 03} mode dominates over themore » other modes in the startup of the oscillation. Via numerical simulation, the generation of the microwave pulse with an output power of 425 MW and a conversion efficiency of 32% are achieved at 60.5 GHz with an external magnetic field of 1.25 T. This RBWO can provide greater power handling capacity when operating on the TM{sub 03} mode than on the TM{sub 01} mode.« less

Strong magnetic coupling in the hexagonal R5Pb3 compounds (R=Gd-Tm)

NASA Astrophysics Data System (ADS)

Marcinkova, Andrea; de la Cruz, Clarina; Yip, Joshua; Zhao, Liang L.; Wang, Jiakui K.; Svanidze, E.; Morosan, E.

2015-06-01

We have synthesized the R5Pb3 (R=Gd-Tm) compounds in polycrystalline form and performed neutron scattering and magnetization measurements. For all R5Pb3 reported here the Weiss temperatures θW are several times smaller than the ordering temperatures TORD, while the latter are remarkably high (TORD up to 275 K for R=Gd) compared to other known R-M binaries (M=Si, Ge, Sn and Sb). The magnetic order changes from ferromagnetic (FM) in R=Gd, Tb to antiferromagnetic (AFM) in R=Dy-Tm. Below TORD, the magnetization measurements together with neutron powder diffraction show complex magnetic behaviors and reveal the existence of up to three additional phase transitions, believed to be a result of large anisotropic exchange and/or crystal electric field effects, induced high anisotropy. The R5Pb3 magnetic unit cells for R=Tb-Tm can be described with incommensurate magnetic wave vectors with spin modulation either along the c axis in R=Tb, Er and Tm, or within the ab plane in R=Dy and Ho.

Recent NASA/GSFC cryogenic measurements of the total hemispheric emissivity of black surface preparations

NASA Astrophysics Data System (ADS)

Tuttle, J.; Canavan, E.

2015-12-01

High-emissivity (black) surfaces are commonly used on deep-space radiators and thermal radiation absorbers in test chambers. Since 2011 NASA Goddard Space Flight Center has measured the total hemispheric emissivity of such surfaces from 20 to 300 K using a test apparatus inside a small laboratory cryostat. We report the latest data from these measurements, including Aeroglaze Z307 paint, Black Kapton, and a configuration of painted aluminum honeycomb that was not previously tested. We also present the results of batch-to- batch reproducibility studies in Ball Infrared BlackTM and painted aluminum honeycomb. Finally, we describe a recently-adopted temperature control method which significantly speeds the data acquisition, and we discuss efforts to reduce the noise in future data.

Preliminary Results of NASA's First Autonomous Formation Flying Experiment: Earth Observing-1 (EO-1)

NASA Technical Reports Server (NTRS)

Folta, David; Hawkins, Albin

2001-01-01

NASA's first autonomous formation flying mission is completing a primary goal of demonstrating an advanced technology called enhanced formation flying. To enable this technology, the Guidance, Navigation, and Control center at the Goddard Space Flight Center has implemented an autonomous universal three-axis formation flying algorithm in executive flight code onboard the New Millennium Program's (NMP) Earth Observing-1 (EO-1) spacecraft. This paper describes the mathematical background of the autonomous formation flying algorithm and the onboard design and presents the preliminary validation results of this unique system. Results from functionality assessment and autonomous maneuver control are presented as comparisons between the onboard EO-1 operational autonomous control system called AutoCon(tm), its ground-based predecessor, and a stand-alone algorithm.

Blue upconversion in Yb3+/Tm3+ co-doped silica fiber based on glass phase-separation technology

NASA Astrophysics Data System (ADS)

Yang, Yu; Chu, Yingbo; Chen, Zhangru; Xing, Yingbin; Hu, Xionwei; Li, Haiqing; Peng, Jinggang; Dai, Nengli; Li, Jinyan; Yang, Luyun

2018-02-01

Yb3+/Tm3+ co-doped silica fiber was prepared successfully by glass phase-separation technology. The measured refractive index profile indicated that the active fiber core had an excellent uniformity. The highest emission intensity was obtained in a sample with a Yb3+ concentration of 0.3 mol/L and a Tm3+ concentration of 0.1 mol/L. Under the excitation at 976 nm, intense blue upconversion emission of Tm3+ at 474 nm was observed due to energy transfer from Yb3+ to Tm3+. A three-photon process was responsible for the blue emission. Due to re-absorption resulted from the Tm3+:3H6→1G4 transition, the blue emission peak was red-shifted. It is suggested that the fiber preparation technology based on glass phase-separation technology can be a potential candidate for preparing active fibers with large core or complex fiber structure.

Wavelength switchable high-power diode-side-pumped rod Tm:YAG Laser around 2µm.

PubMed

Wang, Caili; Du, Shifeng; Niu, Yanxiong; Wang, Zhichao; Zhang, Chao; Bian, Qi; Guo, Chuan; Xu, Jialin; Bo, Yong; Peng, Qinjun; Cui, Dafu; Zhang, Jingyuan; Lei, Wenqiang; Xu, Zuyan

2013-03-25

We report a high-power diode-side-pumped rod Tm:YAG laser operated at either 2.07 or 2.02 µm depending on the transmission of pumped output coupler. The laser yields 115W of continuous-wave output power at 2.07 µm with 5% output coupling, which is the highest output power for all solid-state 2.07 μm cw rod Tm:YAG laser reported so far. With an output coupler of 10% transmission, the center wavelength of the laser is switched to 2.02 μm with an output power of 77.1 W. This is the first observation of high-power wavelength switchable diode-side-pumped rod Tm:YAG laser around 2 µm.

Broadly wavelength tunable acousto-optically Q-switched Tm:Lu2SiO5 laser.

PubMed

Feng, T; Yang, K; Zhao, S; Zhao, J; Qiao, W; Li, T; Zheng, L; Xu, J

2014-09-20

A broadly wavelength tunable acousto-optically Q-switched Tm:Lu2SiO5 (Tm:LSO) laser is presented for the first time, to our best knowledge. The emission wavelength was tuned in a broad spectral region over 111 nm ranging from 1959 to 2070 nm. A shortest pulse duration of 345 ns with beam quality of M(2)≤1.65 was obtained at pulse repetition frequency (PRF) of 1 kHz, corresponding to a maximum single pulse energy of 0.26 mJ and peak power of 0.75 kW. The experimental results indicated that Tm:LSO crystal has outstanding potential for obtaining broadly wavelength tunable and low-PRF laser pulses at 2 μm.

NASA Update.

NASA Image and Video Library

2011-02-15

NASA Deputy Administrator Lori Garver answers questions during a NASA Update on, Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Garver and NASA Administrator Charles Bolden took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2009-07-20

Alan Ladwig, senior advisor to the NASA Administator, far left, makes a point as he introduces NASA Administrator Charles F. Bolden Jr. and Deputy Administrator Lori Garver at a NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

Modulated and continuous-wave operations of low-power thulium (Tm:YAP) laser in tissue welding

NASA Astrophysics Data System (ADS)

Bilici, Temel; Tabakoğlu, Haşim Özgür; Topaloğlu, Nermin; Kalaycıoğlu, Hamit; Kurt, Adnan; Sennaroglu, Alphan; Gülsoy, Murat

2010-05-01

Our aim is to explore the welding capabilities of a thulium (Tm:YAP) laser in modulated and continuous-wave (CW) modes of operation. The Tm:YAP laser system developed for this study includes a Tm:YAP laser resonator, diode laser driver, water chiller, modulation controller unit, and acquisition/control software. Full-thickness incisions on Wistar rat skin were welded by the Tm:YAP laser system at 100 mW and 5 s in both modulated and CW modes of operation (34.66 W/cm2). The skin samples were examined during a 21-day healing period by histology and tensile tests. The results were compared with the samples closed by conventional suture technique. For the laser groups, immediate closure at the surface layers of the incisions was observed. Full closures were observed for both modulated and CW modes of operation at day 4. The tensile forces for both modulated and CW modes of operation were found to be significantly higher than the values found by conventional suture technique. The 1980-nm Tm:YAP laser system operating in both modulated and CW modes maximizes the therapeutic effect while minimizing undesired side effects of laser tissue welding. Hence, it is a potentially important alternative tool to the conventional suturing technique.

Magnetic properties of TM3[Cr(CN)6]2.n H2O

NASA Astrophysics Data System (ADS)

Zentková, M.; Mihalik, M.; Ková, J.; Zentko, A.; Mitróová, Z.; Lukáová, M.; Kaveanský, V.; Kiss, L. F.

2006-01-01

Magnetization measurements performed on Prussian blue analogs TM2+3[CrIII(CN)6]2.n H2O (TM = Cr, Mn, Fe, Co, Ni, Cu) confirmed the dual character of the exchange interaction (antiferromagnetic AFM and ferromagnetic FM) in this system. AFM interaction dominates for the Cr2+ sample and with rising atomic number Z the FM interaction becomes more important reaching pure FM character for the Cu2+ sample.

NASA Quest.

ERIC Educational Resources Information Center

Ashby, Susanne

2000-01-01

Introduces NASA Quest as part of NASA's Learning Technologies Project, which connects students to the people of NASA through the various pages at the website where students can glimpse the various types of work performed at different NASA facilities and talk to NASA workers about the type of work they do. (ASK)

Stages of driving behavior change within the Transtheoretical Model (TM).

PubMed

Kowalski, Kristina; Jeznach, Anna; Tuokko, Holly Anna

2014-09-01

Many older adults voluntarily restrict their driving or stop driving of their own accord. Driving behavior change may occur in stages, as predicted by the Transtheoretical Model of Behavior Change (TM). This study explored the process of older driver behavior change within the TM framework using interviews/focus groups with drivers and former drivers aged 71-94 years. Within those groups of drivers, driving behavior was divided into two classes: those who changed their driving with age and those who did not. Those who changed their driving as they aged included people gradually imposing restrictions ("gradual restrictors") and those making plans in anticipation of stopping driving ("preparers"). Participants who did not change their driving included those who employed lifelong driving restrictions ("consistent") and those who made no changes ("non-changers"). Preliminary support for TM within the driving context was found; however, further exploration of driving behavior change within this framework is warranted. It is important to continue to investigate the factors that might influence driving behavior in older adults. By promoting self-regulation in individuals, it may be possible to help older adults continue to drive, thereby improving older adult's mobility and quality of life. Copyright © 2014 National Safety Council and Elsevier Ltd. All rights reserved.

Compact self-Q-switched Tm:YLF laser at 1.91 μm

NASA Astrophysics Data System (ADS)

Zhang, B.; Li, L.; He, C. J.; Tian, F. J.; Yang, X. T.; Cui, J. H.; Zhang, J. Z.; Sun, W. M.

2018-03-01

We report self-Q-switching operation in a diode-pumped Tm:YLF bulk laser by exploiting saturable re-absorption under the quasi-three-level regime. Robust self-Q-switched pulse output at 1.91 μm in fundamental mode is demonstrated experimentally with 1.5 at.% doped Tm:YLF crystal. At maximum absorbed pump power of 4.5 W, the average output power and pulse energy are obtained as high as 610 mW and 29 μJ, respectively, with the corresponding slope efficiency of 22%. Pulse repetition rate is tunable in the range of 3-21 kHz with changing the pump power. The dynamics of self-Q-switching of Tm:YLF laser are discussed with the help of a rate equation model showing good agreement with the experiment. The compact self-Q-switched laser near 2 μm has potential application in laser radar systems for accurate wind velocity measurements.

NASA Update

NASA Image and Video Library

2011-02-15

NASA Administrator Charles F. Bolden Jr., and Deputy Administrator Lori Garver deliver a NASA Update on, Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2011-02-15

NASA Deputy Administrator Lori Garver listens as NASA Administrator Charles Bolden answers a question during a NASA Update on Tuesday, Feb. 15, 2011, at NASA Headquarters in Washington. Bolden and Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

Nonylphenol regulates cyclooxygenase-2 expression via Ros-activated NF-κB pathway in sertoli TM4 cells.

PubMed

Liu, Xiaozhen; Nie, Shaoping; Huang, Danfei; Xie, Mingyong

2015-09-01

The aim of this study was to investigate the signaling pathways involved in the cyclooxygenase (COX)-2 regulation induced by nonylphenol (NP) in mouse testis Sertoli TM4 cells. Our results showed that treatment of TM4 cells with NP increased COX-2 protein expression and interleukin-6 (IL)-6 and prostaglandin E2 (PGE2) secretion in a dose-dependent manner. Pretreatment with reactive oxygen species (ROS) scavenger, N-acetylcysteine (NAC), attenuated NP-induced ROS production, COX-2 expression, and IL-6 and PGE2 release in TM4 cells. Exposure to NP stimulated activation of NF-κB, whereas the NF-κB inhibitor, pyrrolidine dithiocarbamate, attenuated NP-enhanced COX-2 expression and IL-6 and PGE2 release in TM4 cells in a dose-dependent manner. Furthermore, NAC blocked NP-induced activation of NF-κB. In addition, inhibition of COX-2 mitigated NP-induced IL-6 release. In conclusion, NP induced ROS generation, activation of NF-κB pathway, COX-2 upregulation, and IL-6 and PGE2 secretion in TM4 cells. NP may regulate COX-2 expression via ROS-activated NF-κB pathway in Sertoli TM4 cells. © 2014 Wiley Periodicals, Inc.

Down-Regulation of TM29, a Tomato SEPALLATA Homolog, Causes Parthenocarpic Fruit Development and Floral Reversion1

PubMed Central

Ampomah-Dwamena, Charles; Morris, Bret A.; Sutherland, Paul; Veit, Bruce; Yao, Jia-Long

2002-01-01

We have characterized the tomato (Lycopersicon esculentum Mill.) MADS box gene TM29 that shared a high amino acid sequence homology to the Arabidopsis SEP1, 2, and 3 (SEPALLATA1, 2, and 3) genes. TM29 showed similar expression profiles to SEP1, with accumulation of mRNA in the primordia of all four whorls of floral organs. In addition, TM29 mRNA was detected in inflorescence and vegetative meristems. To understand TM29 function, we produced transgenic tomato plants in which TM29 expression was down-regulated by either cosuppression or antisense techniques. These transgenic plants produced aberrant flowers with morphogenetic alterations in the organs of the inner three whorls. Petals and stamens were green rather than yellow, suggesting a partial conversion to a sepalloid identity. Stamens and ovaries were infertile, with the later developing into parthenocarpic fruit. Ectopic shoots with partially developed leaves and secondary flowers emerged from the fruit. These shoots resembled the primary transgenic flowers and continued to produce parthenocarpic fruit and additional ectopic shoots. Based on the temporal and spatial expression pattern and transgenic phenotypes, we propose that TM29 functions in floral organ development, fruit development, and maintenance of floral meristem identity in tomato. PMID:12376628

Optical absorption and emission bands of Tm 3+ ions in calcium niobium gallium garnet crystal

NASA Astrophysics Data System (ADS)

Tsuboi, Taiju; Tanigawa, Masayuki; Shimamura, Kiyoshi

2000-12-01

Absorption spectra of Tm 3+ ions in Ca 3Nb 1.6875Ga 3.1875O 12 (CNGG) crystal have been investigated at various temperatures between 15 and 296 K. Luminescence spectra in a spectral region of 400-1750 nm are investigated under excitation into various excited states of Tm 3+ and the conduction band of CNGG at room temperature. The absorption and emission bands of Tm 3+ in CNGG are observed to be broader than those observed in other Tm 3+-doped crystals such as LiNbO 3. This is due to the disordered structure of CNGG. From the temperature dependence of absorption spectra, five Stark levels are derived for the 3H 6 ground state. The highest Stark level is found to be 351 cm -1 above the ground level. It is suggested that the low efficiency of the 2.02 μm lasing at room temperature is due to the narrow splitting of the Stark levels.

Highly Tm3+ doped germanate glass and its single mode fiber for 2.0 μm laser

PubMed Central

Wen, Xin; Tang, Guowu; Yang, Qi; Chen, Xiaodong; Qian, Qi; Zhang, Qinyuan; Yang, Zhongmin

2016-01-01

Highly Tm3+ doped optical fibers are urgently desirable for 2.0 μm compact single-frequency fiber laser and high-repetition-rate mode-locked fiber laser. Here, we systematically investigated the optical parameters, energy transfer processes and thermal properties of Tm3+ doped barium gallo-germanate (BGG) glasses. Highly Tm3+ doped BGG glass single mode (SM) fibers were fabricated by the rod-in-tube technique. The Tm3+ doping concentration reaches 7.6 × 1020 ions/cm3, being the reported highest level in Tm3+ doped BGG SM fibers. Using ultra short (1.6 cm) as-drawn highly Tm3+ doped BGG SM fiber, a single-frequency fiber laser at 1.95 μm has been demonstrated with a maximum output power of 35 mW when in-band pumped by a home-made 1568 nm fiber laser. Additionally, a multilongitudinal-mode fiber laser at 1.95 μm has also been achieved in a 10 cm long as-drawn active fiber, yielding a maximum laser output power of 165 mW and a slope efficiency of 17%. The results confirm that the as-drawn highly Tm3+ doped BGG SM fibers are promising in applications that require high gain and high power from a short piece of active optical fiber. PMID:26828920

Molecular cloning and characterization of autophagy-related gene TmATG8 in Listeria-invaded hemocytes of Tenebrio molitor.

PubMed

Tindwa, Hamisi; Jo, Yong Hun; Patnaik, Bharat Bhusan; Lee, Yong Seok; Kang, Sang Sun; Han, Yeon Soo

2015-07-01

Macroautophagy (hereinafter called autophagy) is a highly regulated process used by eukaryotic cells to digest portions of the cytoplasm that remodels and recycles nutrients and disposes of unwanted cytoplasmic constituents. Currently 36 autophagy-related genes (ATG) and their homologs have been characterized in yeast and higher eukaryotes, including insects. In the present study, we identified and functionally characterized the immune function of an ATG8 homolog in a coleopteran insect, Tenebrio molitor (TmATG8). The cDNA of TmATG8 comprises of an ORF of 363 bp that encodes a protein of 120 amino acid residues. TmATG8 transcripts are detected in all the developmental stages analyzed. TmAtg8 protein contains a highly conserved C-terminal glycine residue (Gly116) and shows high amino acid sequence identity (98%) to its Tribolium castaneum homolog, TcAtg8. Loss of function of TmATG8 by RNAi led to a significant increase in the mortality rates of T. molitor larvae against Listeria monocytogenes. Unlike dsEGFP-treated control larvae, TmATG8-silenced larvae failed to turn-on autophagy in hemocytes after injection with L. monocytogenes. These data suggest that TmATG8 play a role in mediating autophagy-based clearance of Listeria in T. molitor. Copyright © 2015 Elsevier Ltd. All rights reserved.

NASA Update

NASA Image and Video Library

2011-02-15

NASA Deputy Associate Administrator for the Office of Communications Bob Jacobs moderates the NASA Update program, Tuesday, Feb. 15, 2011 at NASA Headquarters in Washington. NASA's 12th Administrator Charles Bolden and Deputy Administrator Lori Garver took the time discuss the agency’s fiscal year 2012 budget request and to take questions from employees. Photo Credit: (NASA/Bill Ingalls)

Soyuz-TM-based interim Assured Crew Return Vehicle (ACRV) for the Space Station Freedom

NASA Technical Reports Server (NTRS)

Semenov, Yu. P.; Babkov, Oleg I.; Timchenko, Vladimir A.; Craig, Jerry W.

1993-01-01

The concept of using the available Soyuz-TM Assured Crew Return Vehicle (ACRV) spacecraft for the assurance of the safety of the Space Station Freedom (SSF) crew after the departure of the Space Shuttle from SSF was proposed by the NPO Energia and was accepted by NASA in 1992. The ACRV will provide the crew with the capability to evacuate a seriously injured/ill crewmember from the SSF to a ground-based care facility under medically tolerable conditions and with the capability for a safe evacuation from SSF in the events SSF becomes uninhabitable or the Space Shuttle flights are interrupted for a time that exceeds SSF ability for crew support and/or safe operations. This paper presents the main results of studies on Phase A (including studies on the service life of ACRV; spacecraft design and operations; prelaunch processing; mission support; safety, reliability, maintenance and quality and assurance; landing, and search/rescue operations; interfaces with the SSF and with Space Shuttle; crew accommodation; motion of orbital an service modules; and ACRV injection by the Expendable Launch Vehicles), along with the objectives of further work on the Phase B.

UV- Vis- NIR and luminescent characterization of PZCdO:Tm laser oxide glasses

NASA Astrophysics Data System (ADS)

Al-Assiri, M. S.; Algarni, H.; Reben, M.; Yousef, E.; Hegazy, H. H.; AbouDeif, Y. M.; Umar, Ahmad

2017-11-01

The luminescent oxide glasses with composition 50P2O5- 30ZnO- 20CdO (PZCdO pure) and 50P2O5- 30ZnO- 20CdO- 30000 ppm Tm2O3 (PZCdO:Tm) were synthesized by using melt- quenching technique. The optical energy gap and Urbach energy of these glasses were calculated by using UV-Vis-NIR spectroscopy. Judd- Ofelt parameters Ω2, Ω4 and Ω6, branching ratio, βR, and radiative lifetimes, τR, of Tm3+ ions doped PZCdO glasses were estimated. The spectroscopic results showed that the present glasses has the effective emission cross section bandwidth (Δλeff = 90 nm) and high stimulated emission cross-section (σem = 1.5 × 10-21 cm2). The blue up conversion emissions sharp band at 458 nm corresponding to transition 1D2 → 3F6 and weak emission band in NIR region assigned to 1G4→3H4 for the glasses PZCdO:Tm with UV- excited at 354 nm region were obtained. From result we can suggest that the present glasses can be used for blue light emitting diodes BLED chip.

BOREAS RSS-7 Landsat TM LAI IMages of the SSA and NSA

NASA Technical Reports Server (NTRS)

Hall, Forrest G. (Editor); Nickeson, Jaime (Editor); Chen, Jing; Cihlar, Josef

2000-01-01

The BOReal Ecosystem-Atmosphere Study Remote Sensing Science (BOREAS RSS-7) team used Landsat Thematic Mapper (TM) images processed at CCRS to produce images of Leaf Area Index (LAI) for the BOREAS study areas. Two images acquired on 06-Jun and 09-Aug-1991 were used for the SSA, and one image acquired on 09-Jun-1994 was used for the NSA. The LAI images are based on ground measurements and Landsat TM Reduced Simple Ratio (RSR) images. The data are stored in binary image-format files.

Herman Method[TM]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2010

2010-01-01

The "Herman Method"[TM] teaches reading in small groups of up to three students. The curriculum provides instruction in phonemic awareness, phonics, fluency, vocabulary, and reading comprehension, while also teaching spelling and writing. It contains 20 modules of instruction through a fifth grade level. Each module includes a reading,…

Study of broadband near-infrared emission in Tm3+-Er3+ codoped TeO2-WO3-PbO glasses.

PubMed

Balda, R; Fernández, J; Fernández-Navarro, J M

2009-05-25

In this work, we report the near-infrared emission properties of Tm(3+)-Er(3+) codoped tellurite TeO(2)-WO(3)-PbO glasses under 794 nm excitation. A broad emission from 1350 to 1750 nm corresponding to the Tm(3+) and Er(3+) emissions is observed. The full width at half-maximum of this broadband increases with increasing [Tm]/[Er] concentration ratio up to a value of ~ 160 nm. The energy transfer between Tm(3+) and Er(3+) ions is evidenced by both the temporal behavior of the near-infrared luminescence and the effect of Tm3+ codoping on the visible upconversion of Er(3+) ions.

Influence of Tm+3 concentration on the non-linear optical effects of the BiB3O6 : Tm3+ glass nanoparticle-doped polymer

NASA Astrophysics Data System (ADS)

Majchrowski, A.; Ebothe, J.; Ozga, K.; Kityk, I. V.; Reshak, A. H.; Lukasiewicz, T.; Brik, M. G.

2010-01-01

It is shown that BiB3O6 : Tm3+ glass nanoparticles incorporated into polymethylmethacrylate (PMMA) and polycarbonate (PC) polymer matrices show good second-order susceptibilities under bicolour coherent laser treatment. It is found that only during incorporation into highly polarized PC matrices could one observe an enhancement of the second-order susceptibilities with increasing laser treated power densities. The main increase is observed for all samples at power densities equal to about 0.4 GW cm-2. After passing this value there is a saturation of the output susceptibilities and even an abrupt decrease. The most striking feature is the achievement of second-order susceptibilities equal to about 5 pm V-1 for samples containing 4% nanoparticle (NP) content in the PC matrix. A further increase in the NP concentration to 6% leads to a decrease in susceptibility to 15%. In the case of PMMA matrices these changes do not exceed the background. The same situation is present for the pure BIBO and low-doped Tm materials. The effect is maximal for a low concentration of Tm—about 0.75%. In the case of bulk glasses the intensity dependences of the second-harmonic generation unambiguously show that the achieved maximal values of second-order susceptibilities do not exceed 3 pm V-1 for 0.5% Tm concentration.

NASA Update

NASA Image and Video Library

2009-07-20

NASA Administrator Charles F. Bolden Jr. left, speaks during his first NASA Update as Deputy Administrator Lori Garver looks on,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2009-07-20

NASA Administrator Charles F. Bolden Jr. left, and Deputy Administrator Lori Garver are seen during their first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2009-07-20

NASA Administrator Charles F. Bolden Jr. speaks during his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator, was joined by Deputy Administrator Lori Garver where they took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

Color Tunable and Upconversion Luminescence in Yb-Tm Co-Doped Yttrium Phosphate Inverse Opal Photonic Crystals.

PubMed

Wang, Siqin; Qiu, Jianbei; Wang, Qi; Zhou, Dacheng; Yang, Zhengwen

2016-04-01

For this paper, YPO4: Tm, Yb inverse opals with the photonic band gaps at 475 nm and 655 nm were prepared by polystyrene colloidal crystal templates. We investigated the influence of photonic band gaps on the Tm-Yb upconversion emission which was in the YPO4: Tm Yb inverse opal photonic crystals. Comparing with the reference sample, significant suppression of both the blue and red upconversion luminescence of Tm3+ ions were observed in the inverse opals. The color purity of the blue emission was improved in the inverse opal by the suppression of red upconversion emission. Additionally, mechanism of upconversion emission in the inverse opal was discussed. We believe that the present work will be valuable for not only the foundational study of upconversion emission modification but also the development of new optical devices in upconversion lighting and display.

2 μm emission properties and hydroxy groups quenching of Tm3+ in germanate-tellurite glass

NASA Astrophysics Data System (ADS)

Cai, Muzhi; Lu, Yu; Cao, Ruijie; Tian, Ying; Xu, Shiqing; Zhang, Junjie

2016-07-01

Tm3+ activated germanate-tellurite glasses with good thermal stability and anti-crystallization ability were prepared. Efficient 2 μm fluorescence was observed in the optimal concentration Tm3+ doped glass and the corresponding radiative properties were investigated. For Tm3+: 3F4 → 3H6 transition, high spontaneous radiative transition probability (260.75 s-1) and large emission cross section (7.66 × 10-21 cm2) were obtained from the prepared glass. According to Dexter's and Forster's theory, energy transfer microscopic parameters were computed to elucidate the observed 2 μm emissions in detail. Besides, the effect of hydroxy groups quenching was also quantificationally investigated based on simplified rate equations. Results demonstrate that the optimal concentration Tm3+ doped germanate-tellurite glass possessing excellent spectroscopic properties might be an attractive candidate for 2 μm laser or amplifier.

Development of a coupled FLEXPART-TM5 CO2 inverse modeling system

NASA Astrophysics Data System (ADS)

Monteil, Guillaume; Scholze, Marko

2017-04-01

Inverse modeling techniques are used to derive information on surface CO2 fluxes from measurements of atmospheric CO2 concentrations. The principle is to use an atmospheric transport model to compute the CO2 concentrations corresponding to a prior estimate of the surface CO2 fluxes. From the mismatches between observed and modeled concentrations, a correction of the flux estimate is computed, that represents the best statistical compromise between the prior knowledge and the new information brought in by the observations. Such "top-down" CO2 flux estimates are useful for a number of applications, such as the verification of CO2 emission inventories reported by countries in the framework of international greenhouse gas emission reduction treaties (Paris agreement), or for the validation and improvement of the bottom-up models used in future climate predictions. Inverse modeling CO2 flux estimates are limited in resolution (spatial and temporal) by the lack of observational constraints and by the very heavy computational cost of high-resolution inversions. The observational limitation is however being lifted, with the expansion of regional surface networks such as ICOS in Europe, and with the launch of new satellite instruments to measure tropospheric CO2 concentrations. To make an efficient use of these new observations, it is necessary to step up the resolution of atmospheric inversions. We have developed an inverse modeling system, based on a coupling between the TM5 and the FLEXPART transport models. The coupling follows the approach described in Rodenbeck et al., 2009: a first global, coarse resolution, inversion is performed using TM5-4DVAR, and is used to provide background constraints to a second, regional, fine resolution inversion, using FLEXPART as a transport model. The inversion algorithm is adapted from the 4DVAR algorithm used by TM5, but has been developed to be model-agnostic: it would be straightforward to replace TM5 and/or FLEXPART by other

Pressure distribution from high Reynolds number tests of a NASA SC(3)-0712(B) airfoil in the Langley 0.3-meter transonic cryogenic tunnel

NASA Technical Reports Server (NTRS)

Johnson, W. G., Jr.; Hill, A. S.; Eichmann, O.

1985-01-01

A wind tunnel investigation of a NASA 12-percent-thick, advanced-technology supercritical airfoil was conducted in the Langley 0.3-Meter Transonic Cryogenic Tunnel (TCT). This investigation represents another in the series of NASA/U.S. industry two-dimensional airfoil studies to be completed in the Advanced Technology Airfoil Tests program. Test temperature was varied from 220 K to 96 K at pressures ranging from 1.2 to 4.3 atm. Mach number was varied from 0.50 to 0.80. This investigation was designed to: (1) test a NASA advanced-technology airfoil from low to flight equivalent Reynolds numbers, (2) provide experience in cryogenic wind-tunnel model design and testing techniques, and (3) demonstrate the suitability of the 0.3-m TCT as an airfoil test facility. All the test objectives were met. The pressure data are presented without analysis in tabulated format and as plots of pressure coefficient versus position on the airfoil. This report was prepared for use in conjunction with the aerodynamic coefficient data published in NASA-TM-86371. Data are included which demonstrate the effects of fixed transition. Also included are remarks on the model design and fabrication.

NASA Update

NASA Image and Video Library

2009-07-20

NASA Administrator Charles F. Bolden Jr. left on stage, speaks during his first NASA Update as Deputy Administrator Lori Garver looks on at right,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2009-07-20

NASA Administrator Charles F. Bolden Jr., left on stage, speaks during his first NASA Update as Deputy Administrator Lori Garver looks on at right,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2009-07-20

NASA Deputy Administrator Lori Garver makes a point as she speaks during a NASA Update with Administrator Charles F. Bolden Jr.,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

School Security Solutions: Bringing Corporate Safety to Schools and Colleges with EasyLobbyTM Software.

ERIC Educational Resources Information Center

Pendzick, Richard E.; Downs, Robert L.

2002-01-01

Describes software for electronic visitor management (EVM) called EasyLobbyTM, currently in use in thousands of federal and corporate installations throughout the world and its application for school and campus environments. Explains EasyLobbyTM's use to replace visitor logs, capture and store visitor data electronically, and provide badges that…

Energy transfer and visible-infrared quantum cutting photoluminescence modification in Tm-Yb codoped YPO(4) inverse opal photonic crystals.

PubMed

Wang, Siqin; Qiu, Jianbei; Wang, Qi; Zhou, Dacheng; Yang, Zhengwen

2015-08-01

YPO₄:  Tm, Yb inverse opal photonic crystals were successfully synthesized by the colloidal crystal templates method, and the visible-infrared quantum cutting (QC) photoluminescence properties of YPO₄:  Tm, Yb inverse opal photonic crystals were investigated. We obtained tetragonal phase YPO₄ in all the samples when the samples sintered at 950°C for 5 h. The visible emission intensity of Tm³⁺ decreased significantly when the photonic bandgap was located at 650 nm under 480 nm excitation. On the contrary, the QC emission intensity of Yb³⁺ was enhanced as compared with the no photonic bandgap sample. When the photonic bandgap was located at 480 nm, the Yb³⁺ and Tm³⁺ light-emitting intensity weakened at the same time. We demonstrated that the energy transfer between Tm³⁺ and Yb³⁺ is enhanced by the suppression of the red emission of Tm³⁺. Additionally, the mechanisms for the influence of the photonic bandgap on the energy transfer process of the Tm³⁺, Yb³⁺ codoped YPO₄ inverse opal are discussed.

Physical properties of i-R-Cd quasicrystals(R = Y, Gd-Tm)

NASA Astrophysics Data System (ADS)

Kong, Tai; Bud'Ko, Sergey L.; Jesche, Anton; Goldman, Alan I.; Kreyssig, Andreas; Dennis, Kevin W.; Ramazanoglu, Mehmet; Canfield, Paul C.; McArthur, John

2014-03-01

Detailed characterization of recently discovered i-R-Cd (R = Y, Gd-Tm) binary quasicrystals by means of room-temperature powder x-ray diffraction, dc and ac magnetization, resistivity and specific heat measurements will be presented. i-Y-Cd is weakly diamagnetic. The dc magnetization of i-R-Cd (R = Gd, Ho-Tm) shows typical spin-glass type splitting between field-cooled (FC) and zero-field-cooled (ZFC) data. i-Tb-Cd and i-Dy-Cd do not show a clear cusp in their ZFC dc magnetization. ac magnetization measured on i-Gd-Cd indicates a clear frequency-dependence and the third-order non-linear magnetization, χ3, is consistent with a spin-glass transition. The resistivity for i-R-Cd is of order 100 μΩ cm and weakly temperature-dependent. No feature that can be associated with long-range magnetic order was observed in any of the measurements. Characteristic freezing temperatures for i-R-Cd (R = Gd-Tm) deviate from ideal de Gennes scaling. This work is supported by the US DOE, Basic Energy Sciences under Contract No. DE-AC02-07CH11358.

NASA Update

NASA Image and Video Library

2009-07-20

NASA Administrator Charles F. Bolden Jr. is seen through a television camera monitor during his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator, was joined by Deputy Administrator Lori Garver where they took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

NASA Update

NASA Image and Video Library

2009-07-20

NASA Administrator Charles F. Bolden Jr. is seen on a television camera monitor while speaking at his first NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, NASA's 12th Administrator, was joined by Deputy Administrator Lori Garver where they took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

A procedure for radiometric recalibration of Landsat 5 TM reflective-band data

USGS Publications Warehouse

Chander, G.; Haque, M.O.; Micijevic, E.; Barsi, J.A.

2010-01-01

From the Landsat program's inception in 1972 to the present, the Earth science user community has been benefiting from a historical record of remotely sensed data. The multispectral data from the Landsat 5 (L5) Thematic Mapper (TM) sensor provide the backbone for this extensive archive. Historically, the radiometric calibration procedure for the L5 TM imagery used the detectors' response to the internal calibrator (IC) on a scene-by-scene basis to determine the gain and offset for each detector. The IC system degraded with time, causing radiometric calibration errors up to 20%. In May 2003, the L5 TM data processed and distributed by the U.S. Geological Survey (USGS) Earth Resources Observation and Science Center through the National Landsat Archive Production System (NLAPS) were updated to use a lifetime lookup-table (LUT) gain model to radiometrically calibrate TM data instead of using scene-specific IC gains. Further modification of the gain model was performed in 2007. The L5 TM data processed using IC prior to the calibration update do not benefit from the recent calibration revisions. A procedure has been developed to give users the ability to recalibrate their existing level-1 products. The best recalibration results are obtained if the work-order report that was included in the original standard data product delivery is available. However, if users do not have the original work-order report, the IC trends can be used for recalibration. The IC trends were generated using the radiometric gain trends recorded in the NLAPS database. This paper provides the details of the recalibration procedure for the following: 1) data processed using IC where users have the work-order file; 2) data processed using IC where users do not have the work-order file; 3) data processed using prelaunch calibration parameters; and 4) data processed using the previous version of the LUT (e.g., LUT03) that was released before April 2, 2007.

Positions of the cytoplasmic end of BK α S0 helix relative to S1–S6 and of β1 TM1 and TM2 relative to S0–S6

PubMed Central

Liu, Guoxia; Zakharov, Sergey I.; Yao, Yongneng

2015-01-01

The large-conductance, voltage- and Ca2+-gated K+ (BK) channel consists of four α subunits, which form a voltage- and Ca2+-gated channel, and up to four modulatory β subunits. The β1 subunit is expressed in smooth muscle, where it slows BK channel kinetics and shifts the conductance–voltage (G-V) curve to the left at [Ca2+] > 2 µM. In addition to the six transmembrane (TM) helices, S1–S6, conserved in all voltage-dependent K+ channels, BK α has a unique seventh TM helix, S0, which may contribute to the unusual rightward shift in the G-V curve of BK α in the absence of β1 and to a leftward shift in its presence. Such a role is supported by the close proximity of S0 to S3 and S4 in the voltage-sensing domain. Furthermore, on the extracellular side of the membrane, one of the two TM helices of β1, TM2, is adjacent to S0. We have now analyzed induced disulfide bond formation between substituted Cys residues on the cytoplasmic side of the membrane. There, in contrast, S0 is closest to the S2–S3 loop, from which position it is displaced on the addition of β1. The cytoplasmic ends of β1 TM1 and TM2 are adjacent and are located between the S2–S3 loop of one α subunit and S1 of a neighboring α subunit and are not adjacent to S0; i.e., S0 and TM2 have different trajectories through the membrane. In the absence of β1, 70% of disulfide bonding of W43C (S0) and L175C (S2–S3) has no effect on V50 for activation, implying that the cytoplasmic end of S0 and the S2–S3 loop move in concert, if at all, during activation. Otherwise, linking them together in one state would obstruct the transition to the other state, which would certainly change V50. PMID:25667410

Use of Semivariances for Studies of Landsat TM Image Textural Properties of Loblolly Pine Forests

Treesearch

Jarek Zawadzki; Chris J. Cieszewski; Roger C. Lowe; Michael Zasada

2005-01-01

We evaluate the applicability of Landsat TM imagery for analyzing textural information of pine forest images by exploring the spatial correlation between pixels measured by semivariances and cross-semivariances calculated from transects of the Landsat TM images. Then, we explore differences in semivariances associated with images of young, middle-aged, and old, and...

Effect of [Li]/[Nb] ratio on composition and defect structure of Zr:Yb:Tm:LiNbO3 crystals

NASA Astrophysics Data System (ADS)

Liu, Chunrui; Dai, Li; Wang, Luping; Shao, Yu; Yan, Zhehua; Xu, Yuheng

2018-04-01

Zr:Yb:Tm:LiNbO3 crystals with various [Li]/[Nb] ratios (0.946, 1.05, 1.20 and 1.38) were grown by the Czochralski technique. Distribution coefficients of Zr4+, Yb3+ and Tm3+ ions were analyzed by the inductively coupled plasma-atomic emission spectrometer (ICP-AES). The influence of [Li]/[Nb] ratio on the composition and defect structure of Zr:Yb:Tm:LiNbO3 crystals was investigated by X-ray diffraction and IR transmission spectrum. The results show that as the [Li]/[Nb] ratio increases in the melt, the distribution coefficients of Yb3+ and Tm3+ ions both increase while that of Zr4+ ion deceases. When the [Li]/[Nb] ratio increases to 1.20 in the melt, Zr:Yb:Tm:LiNbO3 crystal is nearly stoichiometric. In addition, when the [Li]/[Nb] ratio reaches up to 1.38, NbLi4+ are completely replaced and Li+ starts to impel the Zr4+, Yb3+ and Tm3+ into the normal Li sites.

Theoretical model predictions and experimental results for a wavelength switchable Tm:YAG laser.

PubMed

Niu, Yanxiong; Wang, Caili; Liu, Wenwen; Niu, Haisha; Xu, Bing; Man, Da

2014-07-01

We present a theoretical model study of a quasi-three-level laser with particular attention given to the Tm:YAG laser. The oscillating conditions of this laser were theoretically analyzed from the point of the pump threshold while taking into account reabsorption loss. The laser oscillation at 2.02 μm with large stimulated emission sections was suppressed by selecting the appropriate coating for the cavity mirrors, then an efficient laser-diode side-pumped continuous-wave Tm:YAG crystal laser operating at 2.07 μm was realized. Experiments with the Tm:YAG laser confirmed the accuracy of the model, and the model was able to accurately predict that the high Stark sub-level within the H3₆ ground state manifold has a low laser threshold and long laser wavelength, which was achieved by decreasing the transmission of the output coupler.

An Excel[TM] Model of a Radioactive Series

ERIC Educational Resources Information Center

Andrews, D. G. H.

2009-01-01

A computer model of the decay of a radioactive series, written in Visual Basic in Excel[TM], is presented. The model is based on the random selection of cells in an array. The results compare well with the theoretical equations. The model is a useful tool in teaching this aspect of radioactivity. (Contains 4 figures.)

Compact, High Energy 2-micron Coherent Doppler Wind Lidar Development for NASA's Future 3-D Winds Measurement from Space

NASA Technical Reports Server (NTRS)

Singh, Upendra N.; Koch, Grady; Yu, Jirong; Petros, Mulugeta; Beyon, Jeffrey; Kavaya, Michael J.; Trieu, Bo; Chen, Songsheng; Bai, Yingxin; Petzar, paul;

Cr:ZnSe laser pumped with Tm:YAP microchip laser

NASA Astrophysics Data System (ADS)

Koranda, Petr; Sulc, Jan; Doroshenko, Maxim; Jelinková, Helena; Basiev, Tasoltan T.; Osiko, Vjatcheslav; Badikov, V. V.; Badikov, D.

2010-02-01

Cr:ZnSe laser coherently longitudinally pumped with Tm:YAP microchip laser was realised. The pumping laser consisted of Tm:YAP crystal (3x3 mm) with resonator mirrors deposited directly on its faces (on rear face the dielectric layer with high reflectance for 1998 nm wavelength and high transmittance for 790 nm pumping radiation wavelength; on output face the dielectric layer with reflectance 97% at 1998 nm wavelength). The maximal output power was 5.5 W and the generated radiation wavelength was 1998 nm. The main advantage of this pumping was stable and still output without relaxation spikes (non-spiking). The Tm:YAP laser radiation was collimated and focused by the set of two CaF2 lenses. The pumping beam spot diameter inside the Cr:ZnSe crystal was 300 μm. The Cr:ZnSe laser resonator consisted of flat rear mirror (HT at 1998 nm and HR at 2100 - 2900 nm) and curved output coupler (r = -150 mm, R = 95% at 2100 - 2700 nm). The maximal output energy of stable radiation was 4 mJ (pulse duration 10 ms, repetition rate 10 Hz). For wavelength tuning the Lyott filter (quartz plate under Brewster angle) was placed between the Cr:ZnSe crystal and output coupler. The generated radiation wavelength was continuously tunable from 2246 - 2650 nm.

Commercialization of Medium Voltage HTS Triax TM Cable Systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Knoll, David

2012-12-31

The original project scope that was established in 2007 aimed to install a 1,700 meter (1.1 mile) medium voltage HTS Triax{TM} cable system into the utility grid in New Orleans, LA. In 2010, however, the utility partner withdrew from the project, so the 1,700 meter cable installation was cancelled and the scope of work was reduced. The work then concentrated on the specific barriers to commercialization of HTS cable technology. The modified scope included long-length HTS cable design and testing, high voltage factory test development, optimized cooling system development, and HTS cable life-cycle analysis. In 2012, Southwire again analyzed themore » market for HTS cables and deemed the near term market acceptance to be low. The scope of work was further reduced to the completion of tasks already started and to testing of the existing HTS cable system in Columbus, OH. The work completed under the project included: • Long-length cable modeling and analysis • HTS wire evaluation and testing • Cable testing for AC losses • Optimized cooling system design • Life cycle testing of the HTS cable in Columbus, OH • Project management. The 200 meter long HTS Triax{TM} cable in Columbus, OH was incorporated into the project under the initial scope changes as a test bed for life cycle testing as well as the site for an optimized HTS cable cooling system. The Columbus cable utilizes the HTS TriaxTM design, so it provided an economical tool for these of the project tasks.« less

Goddard Space Flight Center specification for Helical-Scan 8-millimeter (mm) magnetic digital data tape cartridge

NASA Technical Reports Server (NTRS)

Perry, Jimmy L.

1992-01-01

The same kind of standard and controls are established that are currently in use for the procurement of new analog, digital, and IBM/IBM compatible 3480 tape cartridges, and 1 in wide channel video magnetic tapes. The Magnetic Tape Certification Facility (MTCF) maintains a Qualified Products List (QPL) for the procurement of new magnetic media and uses the following specifications for the QPL and Acceptance Tests: (1) NASA TM-79724 is used for the QPL and Acceptance Testing of new analog magnetic tapes; (2) NASA TM-80599 is used for the QPL and Acceptance Testing of new digital magnetic tapes; (3) NASA TM-100702 is used for the QPL and Acceptance Testing of new IBM/IBM compatible 3840 magnetic tape cartridges; and (4) NASA TM-100712 is used for the QPL and Acceptance Testing of new 1 in wide channel video magnetic tapes. This document will be used for the QPL and Acceptance Testing of new Helical Scan 8 mm digital data tape cartridges.

NPOESS C3S Expandability: SafetyNetTM and McMurdo Improvements

NASA Astrophysics Data System (ADS)

Jamilkowski, M. L.; Paciaroni, J.; Pela, F.

2010-12-01

The National Oceanic & Atmospheric Administration (NOAA), Department of Defense (DoD), and National Aeronautics & Space Administration (NASA) are jointly acquiring the next-generation weather & environmental satellite system; the National Polar-orbiting Operational Environmental Satellite System (NPOESS). NPOESS replaces the current NOAA Polar-orbiting Operational Environmental Satellites (POES) and Dod's Defense Meteorological Satellite Program (DMSP). The NPOESS satellites carry a suite of sensors that collect meteorological, oceanographic, climatological, and solar-geophysical observations of the earth, atmosphere, and space. The command & telemetry portion of NPOESS is the Command, Control and Communications Segment (C3S), developed by Raytheon Intelligence & Information Systems. C3S is responsible for managing the overall NPOESS mission from control and status of the space and ground assets to ensuring delivery of timely, high quality data from the Space Segment (SS) to the Interface Data Processing Segment (IDPS) for processing. In addition, the C3S provides the globally distributed ground assets necessary to collect and transport mission, telemetry, and command data between the satellites and the processing locations. The C3S provides all functions required for day-to-day commanding & state-of-health monitoring of the NPP & NPOESS satellites, and delivery of Stored Mission Data (SMD) to each US Weather Central Interface Data Processor (IDP) for data products development and transfer to System subscribers. The C3S also monitors and reports system-wide health and status & data communications with external systems and between NPOESS segments. Two crucial elements of NPOESS C3S expandability are SafetyNetTM and communications improvements to McMurdo Station, Antarctica. SafetyNetTM is a key feature of NPOESS and a vital element of the C3S and Northrop Grumman Aerospace Systems patented data collection architecture. The centerpiece of SafetyNetTM is the system of

NASA Releases 'NASA App HD' for iPad

NASA Image and Video Library

2012-07-06

The NASA App HD invites you to discover a wealth of NASA information right on your iPad. The application collects, customizes and delivers an extensive selection of dynamically updated mission information, images, videos and Twitter feeds from various online NASA sources in a convenient mobile package. Come explore with NASA, now on your iPad. 2012 Updated Version - HD Resolution and new features. Original version published on Sept. 1, 2010.

Experimental study of a VBG-based Tm : YLF slab laser at different output coupler parameters

DOE Office of Scientific and Technical Information (OSTI.GOV)

Duan, X M; Ding, Y; Dai, T Y

2015-04-30

The performance of a Tm : YLF slab laser is studied at different output coupler parameters. Use is made of a 20-mm-long a-cut slab crystal doped with 2.5 at. % thulium ions. With a volume Bragg grating and a Fabry – Perot etalon, the selected output wavelength of this Tm : YLF slab laser is 1908 nm. For the optimised output coupler with a transmission of 20% and a radius of curvature of 300 mm, the output power exceeds 74.1 W and the slope efficiency with respect to the absorbed pump power reaches 48.4%. In addition, the beam quality ofmore » the Tm : YLF slab laser is improved. (lasers)« less

14 CFR 1240.105 - Special procedures-NASA and NASA contractor employees.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 14 Aeronautics and Space 5 2012-01-01 2012-01-01 false Special procedures-NASA and NASA contractor...—NASA and NASA contractor employees. (a) A NASA Headquarters office, a NASA field installation, or a NASA contractor may submit to the Board an application for an award identifying the originator(s) of...

14 CFR 1240.105 - Special procedures-NASA and NASA contractor employees.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Special procedures-NASA and NASA contractor...—NASA and NASA contractor employees. (a) A NASA Headquarters office, a NASA field installation, or a NASA contractor may submit to the Board an application for an award identifying the originator(s) of...

14 CFR 1240.105 - Special procedures-NASA and NASA contractor employees.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Special procedures-NASA and NASA contractor...—NASA and NASA contractor employees. (a) A NASA Headquarters office, a NASA field installation, or a NASA contractor may submit to the Board an application for an award identifying the originator(s) of...

TM4SF1 promotes the self-renewal of esophageal cancer stem-like cells and is regulated by miR-141.

PubMed

Xue, Lei; Yu, Xiying; Jiang, Xingran; Deng, Xin; Mao, Linlin; Guo, Liping; Fan, Jinhu; Fan, Qinqxia; Wang, Liuxing; Lu, Shih-Hsin

2017-03-21

Cancer stem-like cells have been identified in primary human tumors and cancer cell lines. Previously we found TM4SF1 gene was highly expressed in side population (SP) cells from esophageal squamous cell carcinoma (ESCC) cell lines, but the role and underlying mechanism of TM4SF1 in ESCC remain unclear. In this study, we observed TM4SF1 was up-regulated but miR-141 was down-regulated in SP cells isolated from ESCC cell lines. TM4SF1 could stimulate the self-renewal ability and carcinogenicity of esophageal cancer stem-like cells, and promote cell invasion and migration. In miR-141 overexpression cells, the expression of TM4SF1 was significantly reduced. We also found that overexpression of miR-141 could abolish the self-renewal ability and carcinogenicity of esophageal cancer stem-like cells and decrease cell invasion and migration by suppressing TM4SF1. Consequently, TM4SF1 is a direct target gene of miR-141. The regulation of TM4SF1 by miR-141 may play an important role in controlling self-renewals of esophageal cancer stem-like cells. It may also promote the development of new therapeutic strategies and efficient drugs to target ESCC stem-like cells.

NASA Social

NASA Image and Video Library

2012-05-19

A NASA Social follower holds up a mobile device as NASA Administrator Charles Bolden, left, and Kennedy Space Center director Robert Cabana appear at the NASA Social event, Friday morning, May 19, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

Increased sensitivity to protein synthesis inhibitors in cells lacking tmRNA.

PubMed Central

de la Cruz, J; Vioque, A

2001-01-01

tmRNA (also known as SsrA or 10Sa RNA) is involved in a trans-translation reaction that contributes to the recycling of stalled ribosomes at the 3' end of an mRNA lacking a stop codon or at an internal mRNA cluster of rare codons. Inactivation of the ssrA gene in most bacteria results in viable cells bearing subtle phenotypes, such as temperature-sensitive growth. Herein, we report on the functional characterization of the ssrA gene in the cyanobacterium Synechocystis sp. strain PCC6803. Deletion of the ssrA gene in Synechocystis resulted in viable cells with a growth rate identical to wild-type cells. However, null ssrA cells (deltassrA) were not viable in the presence of the protein synthesis inhibitors chloramphenicol, lincomycin, spiramycin, tylosin, erythromycin, and spectinomycin at low doses that do not significantly affect the growth of wild-type cells. Sensitivity of deltassrA cells similar to wild-type cells was observed with kasugamycin, fusidic acid, thiostrepton, and puromycin. Antibiotics unrelated to protein synthesis, such as ampicillin or rifampicin, had no differential effect on the deltassrA strain. Furthermore, deletion of the ssrA gene is sufficient to impair global protein synthesis when chloramphenicol is added at sublethal concentrations for the wild-type strain. These results indicate that ribosomes stalled by some protein synthesis inhibitors can be recycled by tmRNA. In addition, this suggests that the first elongation cycle with tmRNA, which incorporates a noncoded alanine on the growing peptide chain, may have mechanistic differences with the normal elongation cycles that bypasses the block produced by these specific antibiotics. tmRNA inactivation could be an useful therapeutic target to increase the sensitivity of pathogenic bacteria against antibiotics. PMID:11780628

Tm:germanate Fiber Laser for Planetary Water Vapor Atmospheric Profiling

NASA Technical Reports Server (NTRS)

Barnes, Norman P.; De Young, Russell

2009-01-01

The atmospheric profiling of water vapor is necessary for finding life on Mars and weather on Earth. The design and performance of a water vapor lidar based on a Tm:germanate fiber laser is presented.

Evaluation of Petrifilms(TM) as a diagnostic test to detect bovine mastitis organisms in Kenya.

PubMed

Gitau, George K; Bundi, Royford M; Vanleeuwen, John; Mulei, Charles M

2013-03-01

The study purpose was to validate Petrifilms(TM) (3M Microbiology, 2005) against standard culture methods in the diagnosis of bovine mastitis organisms in Kenya. On 128 smallholder dairy cattle farms in Kenya, between June 21, 2010 and August 31, 2010, milk samples from 269 cows that were positive on California Mastitis Test (CMT) were cultured using standard laboratory culture methods and Petrifilms(TM) (Aerobic Count and Coliform Count -3M Microbiology, 2005), and results were compared. Staphylococcus aureus was the most common bacterium isolated (73 % of samples). Clinical mastitis was found in only three cows, and there were only two Gram-negative isolates, making it impossible to examine the agreement between the two tests for Gram-negative- or clinical mastitis samples. The observed agreement between the standard culture and Petrifilm(TM) (3M Microbiology, 2005) results for Gram-positive isolates was 85 %, and there was fair agreement beyond that expected due to chance alone, with a kappa (κ) of 0.38. Using culture results as a gold standard, the Petrifilms(TM) had a sensitivity of 90 % for Gram-positive samples and specificity of 51 %. With 87 % of CMT-positive samples resulting in Gram-positive pathogens cultured, there was a positive predictive value of 93 % and a negative predictive value of 43 %. Petrifilms(TM) should be considered for culture of mastitis organisms in developing countries, especially when Gram-positive bacteria are expected.

Spectroscopy and energy transfer in lead borate glasses doubly doped with Tm3+ and Dy3+ ions

NASA Astrophysics Data System (ADS)

Górny, Agata; Sołtys, Marta; Pisarska, Joanna; Pisarski, Wojciech A.

2018-03-01

Lead borate glasses singly and doubly doped with Tm3+ and Dy3+ were prepared by traditional melt-quenching technique. The emission spectra of rare earths in studied glass systems were registered under different excitation wavelengths. The observed emission bands are located in the visible spectral region. They correspond to 1D2 → 3F4 (blue) and 1G4 → 3H6 (blue) transitions of Tm3+ as well as 4F9/2 → 6H15/2 (blue), 4F9/2 → 6H13/2 (yellow) and 4F9/2 → 6H11/2 (red) transitions of Dy3+. Moreover, the energy transfer process from Tm3+ to Dy3+ was observed. The luminescence bands originating to characteristic transitions of thulium and dysprosium ions are present on emission spectra under direct excitation of Tm3+. Luminescence lifetimes for the excited states of Tm3+ and Dy3+ ions in lead borate glass were also determined based on decay measurements. The luminescence intensities and lifetimes depend significantly on the relative concentrations of the optically active dopants.

Self-mode-locking operation of a diode-end-pumped Tm:YAP laser with watt-level output power

NASA Astrophysics Data System (ADS)

Zhang, Su; Zhang, Xinlu; Huang, Jinjer; Wang, Tianhan; Dai, Junfeng; Dong, Guangzong

2018-03-01

We report on a high power continuous wave (CW) self-mode-locked Tm:YAP laser pumped by a 792 nm laser diode. Without any additional mode-locking elements in the cavity, stable and self-starting mode-locking operation has been realized. The threshold pump power of the CW self-mode-locked Tm:YAP laser is only 5.4 W. The maximum average output power is as high as 1.65 W at the pump power of 12 W, with the repetition frequency of 468 MHz and the center wavelength of 1943 nm. To the best of our knowledge, this is the first CW self-mode-locked Tm:YAP laser. The experiment results show that the Tm:YAP crystal is a promising gain medium for realizing the high power self-mode-locking operation at 2 µm.

Psychometric Evaluation of the Team Member Perspectives of Person-Centered Care (TM-PCC) Survey for Long-Term Care Homes.

PubMed

Boscart, Veronique M; Davey, Meaghan; Ploeg, Jenny; Heckman, George; Dupuis, Sherry; Sheiban, Linda; Luh Kim, Jessica; Brown, Paul; Sidani, Souraya

2018-06-06

Person-centered care (PCC) is fundamental for providing high-quality care in long-term care homes. This study aimed to evaluate the psychometric properties of an 11-item Team Member Perspectives of Person-Centered Care (TM-PCC) survey, adapted from White and colleagues (2008). In a cross-sectional study, 461 staff from four long-term care homes in Ontario, Canada, completed the TM-PCC. Construct validity and internal consistency of the TM-PCC were examined with a principal component analysis and Cronbach’s alpha coefficient. Findings revealed a three-component structure with factor 1, Supporting Social Relationships; factor 2, Familiarity with Residents’ Preferences; and factor 3, Meaningful Resident⁻Staff Relationships. The TM-PCC, as compared to the original survey, presented with less components (i.e., did not address Resident Autonomy, Personhood, Comfort, Work with Residents, Personal Environment, and Management Structure), yet included one new component (Meaningful Resident⁻Staff Relationships). The TM-PCC has a similar internal consistency (Cronbach’s alpha coefficient 0.82 vs. White et al. 0.74⁻0.91). The TM-PCC can be used to assess PCC from the staff’s perspective in long-term care homes.

The NASA SCI Files[TM]: The Case of the Shaky Quake. A Lesson Guide with Activities in Mathematics, Science, and Technology.

ERIC Educational Resources Information Center

Ricles, Shannon

The NASA SCI Files is a series of instructional programs consisting of broadcast, print, and online elements emphasizing standards-based instruction, problem-based learning, and science as inquiry. The series seeks to motivate students in grades 3-5 to become critical thinkers and active problem solvers. In this program, the tree house detectives…

Using Interdisciplinary Research Methods to Revise and Strengthen the NWS TsunamiReadyTM Community Recognition Program

NASA Astrophysics Data System (ADS)

Scott, C.; Gregg, C. E.; Ritchie, L.; Stephen, M.; Farnham, C.; Fraser, S. A.; Gill, D.; Horan, J.; Houghton, B. F.; Johnson, V.; Johnston, D.

2013-12-01

The National Tsunami Hazard Mitigation Program (NTHMP) partnered with the National Weather Service (NWS) in early 2000 to create the TsunamiReadyTM Community Recognition program. TsunamiReadyTM, modeled after the older NWS StormReadyTM program, is designed to help cities, towns, counties, universities and other large sites in coastal areas reduce the potential for disastrous tsunami-related consequences. To achieve TsunamiReadyTM recognition, communities must meet certain criteria aimed at better preparing a community for tsunami, including specific actions within the following categories: communications and coordination, tsunami warning reception, local warning dissemination, community preparedness, and administration. Using multidisciplinary research methods and strategies from Public Health; Psychology; Political, Social and Physical Sciences and Evaluation, our research team is working directly with a purposive sample of community stakeholders in collaboration and feedback focus group sessions. Invitation to participate is based on a variety of factors including but not limited to an individual's role as a formal or informal community leader (e.g., in business, government, civic organizations), or their organization or agency affiliation to emergency management and response. Community organizing and qualitative research methods are being used to elicit discussion regarding TsunamiReadyTM requirements and the division of requirements based on some aspect of tsunami hazard, vulnerability and risk, such as proximity to active or passive plate margins or subduction zone generated tsunamis versus earthquake-landslide generated tsunamis . The primary aim of this research is to use social science to revise and refine the NWS TsunamiReadyTM Guidelines in an effort to better prepare communities to reduce risk to tsunamis.

NASA Team Collaboration Pilot: Enabling NASA's Virtual Teams

NASA Technical Reports Server (NTRS)

Prahst, Steve

2003-01-01

Most NASA projects and work activities are accomplished by teams of people. These teams are often geographically distributed - across NASA centers and NASA external partners, both domestic and international. NASA "virtual" teams are stressed by the challenge of getting team work done - across geographic boundaries and time zones. To get distributed work done, teams rely on established methods - travel, telephones, Video Teleconferencing (NASA VITS), and email. Time is our most critical resource - and team members are hindered by the overhead of travel and the difficulties of coordinating work across their virtual teams. Modern, Internet based team collaboration tools offer the potential to dramatically improve the ability of virtual teams to get distributed work done.

Detection of soil erosion within pinyon-juniper woodlands using Thematic Mapper (TM) satellite data

NASA Technical Reports Server (NTRS)

Price, Kevin P.; Ridd, Merrill K.

1991-01-01

The sensitivity of Landsat TM data for detecting soil erosion within pinyon-juniper woodlands, and the potential of the spectral data for assigning the universal soil loss equation (USLE) crop managemnent (C) factor to varying cover types within the woodlands are assessed. Results show greatly accelerated rates of soil erosion on pinyon-juniper sites. Percent cover by pinyon-juniper, total soil-loss, and total nonliving ground cover accounted for nearly 70 percent of the variability in TM channels 2, 3, 4, and 5. TM spectral data were consistently better predictors of soil erosion than the biotic and abiotic field variables. Satellite data were more sensitive to vegetation variation than the USLE C factor, and USLE was found to be a poor predictor of soil loss on pinyon-juniper sites. A new string-to-ground soil erosion prediction technique is introduced.

Microstructure-property relationships in Al-Cu-Li-Ag-Mg Weldalite (tm) alloys, part 2

NASA Technical Reports Server (NTRS)

Langan, T. J.; Pickens, J. R.

1991-01-01

The microstructure and mechanical properties of the ultrahigh strength Al-Cu-Li-Ag-Mg alloy, Weldalite (tm) 049, were studied. Specifically, the microstructural features along with tensile strength, weldability, Young's modulus and fracture toughness were studied for Weldalite (tm) 049 type alloys with Li contents ranging from 1.3 to 1.9 wt. pct. The tensile properties of Weldalite 049 and Weldalite 049 reinforced with TiB2 particles fabricated using the XD (tm) process were also evaluated at cryogenic, room, and elevated temperatures. In addition, an experimental alloy, similar in composition to Weldalite 049 but without the Ag+Mg, was fabricated. The microstructure of this alloy was compared with that of Weldalite 049 in the T6 condition to assess the effect of Ag+Mg on nucleation of strengthening phases in the absence of cold work.

Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments.

PubMed

Kim, Hye-Jin; Kwon, Sojung; Nam, Seo Hee; Jung, Jae Woo; Kang, Minkyung; Ryu, Jihye; Kim, Ji Eon; Cheong, Jin-Gyu; Cho, Chang Yun; Kim, Somi; Song, Dae-Geun; Kim, Yong-Nyun; Kim, Tai Young; Jung, Min-Kyo; Lee, Kyung-Min; Pack, Chan-Gi; Lee, Jung Weon

2017-04-01

Membrane proteins sense extracellular cues and transduce intracellular signaling to coordinate directionality and speed during cellular migration. They are often localized to specific regions, as with lipid rafts or tetraspanin-enriched microdomains; however, the dynamic interactions of tetraspanins with diverse receptors within tetraspanin-enriched microdomains on cellular surfaces remain largely unexplored. Here, we investigated effects of tetraspan(in) TM4SF5 (transmembrane 4 L6 family member 5)-enriched microdomains (T 5 ERMs) on the directionality of cell migration. Physical association of TM4SF5 with epidermal growth factor receptor (EGFR) and integrin α5 was visualized by live fluorescence cross-correlation spectroscopy and higher-resolution microscopy at the leading edge of migratory cells, presumably forming TM4SF5-enriched microdomains. Whereas TM4SF5 and EGFR colocalized at the migrating leading region more than at the rear, TM4SF5 and integrin α5 colocalized evenly throughout cells. Cholesterol depletion and disruption in TM4SF5 post-translational modifications, including N -glycosylation and palmitoylation, altered TM4SF5 interactions and cellular localization, which led to less cellular migration speed and directionality in 2- or 3-dimensional conditions. TM4SF5 controlled directional cell migration and invasion, and importantly, these TM4SF5 functions were dependent on cholesterol, TM4SF5 post-translational modifications, and EGFR and integrin α5 activity. Altogether, we showed that TM4SF5 dynamically interacted with EGFR and integrin α5 in migratory cells to control directionality and invasion.-Kim, H.-J., Kwon, S., Nam, S. H., Jung, J. W., Kang, M., Ryu, J., Kim, J. E., Cheong, J.-G., Cho, C. Y., Kim, S., Song, D.-G., Kim, Y.-N., Kim, T. Y., Jung, M.-K., Lee, K.-M., Pack, C.-G., Lee, J. W. Dynamic and coordinated single-molecular interactions at TM4SF5-enriched microdomains guide invasive behaviors in 2- and 3-dimensional environments. © FASEB.

NASA Update

NASA Image and Video Library

2009-07-20

Alan Ladwig, Senior Advisor to the NASA Administrator, introduces Administrator Charles F. Bolden Jr. and Deputy Administrator Lori Garver at a NASA Update,Tuesday, July 21, 2009, at NASA Headquarters in Washington. Bolden, the agency's 12th Administrator and Garver took the time to introduce themselves and outline their vision for the agency going forward. No questions were taken during the session. Photo Credit: (NASA/Bill Ingalls)

NASA Social

NASA Image and Video Library

2011-05-18

Ed Mango, of the NASA Commercial Crew Office, speaks during a NASA Social, Friday, May 18, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

Doors to Discovery[TM]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2013

2013-01-01

"Doors to Discovery"]TM] is a preschool literacy curriculum that uses eight thematic units of activities to help children build fundamental early literacy skills in oral language, phonological awareness, concepts of print, alphabet knowledge, writing, and comprehension. The eight thematic units cover topics such as nature, friendship,…

Non-explosive actuation for the ORBCOMM (TM) satellite

NASA Technical Reports Server (NTRS)

Robinson, Anthony; Courtney, Craig; Moran, Tom

1995-01-01

Spool-based non-explosive actuator (NEA) devices are used for three important holddown and release functions during the establishment of the ORBCOMM (TM) constellation. Non-explosive separation nuts are used to restrain and release the 26 individual satellites into low earth orbit. Cable release mechanisms based on the same technology are used to release the solar arrays and antenna boom.

An ELISA using recombinant TmHSP70 for the diagnosis of Taenia multiceps infections in goats.

PubMed

Wang, Yu; Nie, Huaming; Gu, Xiaobin; Wang, Tao; Huang, Xing; Chen, Lin; Lai, Weimin; Peng, Xuerong; Yang, Guangyou

2015-09-15

Infections with the tapeworm Taenia multiceps are problematic for ruminant farming worldwide. Here we develop a novel and rapid method for serodiagnosis of T. multiceps infections via an indirect ELISA (iELISA) that uses a heat shock protein, namely, TmHSP70. We extracted the total RNA of T. multiceps from the protoscoleces of cysts dissected from the brains of infected goats. Subsequently, we successfully amplified, cloned and expressed the TmHSP70 gene in Escherichia coli BL21 (DE3). Western blot analysis showed that the recombinant protein (∼34 kDa molecular weight) was recognized by the coenurosis positive serum. Given these initial, robust immunogenic properties for recombinant TmHSP protein, we assessed the ELISA-based serodiagnostic potential of this gene. The indirect ELISA was then optimized to 2.70 μg/well dilution for antigen and 1:80 dilution for serum,while the cut-off value is 0.446. We report that our novel TmHSP ELISA detected T. multiceps sera with a sensitivity of 1:10240 and a specificity of 83.3% (5/6). In a preliminary application, this assay correctly confirmed T. multiceps infection in 30 infected goats, consistent with the clinical examination. This study has revealed that our novel iELISA, which uses the rTmHSP protein, provides a rapid test for diagnosing coenurosis. Copyright © 2015 Elsevier B.V. All rights reserved.

'2TM proteins': an antigenically diverse superfamily with variable functions and export pathways.

PubMed

Kaur, Jasweer; Hora, Rachna

2018-01-01

Malaria is a disease that affects millions of people annually. An intracellular habitat and lack of protein synthesizing machinery in erythrocytes pose numerous difficulties for survival of the human pathogen Plasmodium falciparum . The parasite refurbishes the infected red blood cell (iRBC) by synthesis and export of several proteins in an attempt to suffice its metabolic needs and evade the host immune response. Immune evasion is largely mediated by surface display of highly polymorphic protein families known as variable surface antigens. These include the two trans-membrane (2TM) superfamily constituted by multicopy repetitive interspersed family (RIFINs), subtelomeric variable open reading frame (STEVORs) and Plasmodium falciparum Maurer's cleft two trans-membrane proteins present only in P. falciparum and some simian infecting Plasmodium species. Their hypervariable region flanked by 2TM domains exposed on the iRBC surface is believed to generate antigenic diversity. Though historically named "2TM superfamily," several A-type RIFINs and some STEVORs assume one trans-membrane topology. RIFINs and STEVORs share varied functions in different parasite life cycle stages like rosetting, alteration of iRBC rigidity and immune evasion. Additionally, a member of the STEVOR family has been implicated in merozoite invasion. Differential expression of these families in laboratory strains and clinical isolates propose them to be important for host cell survival and defense. The role of RIFINs in modulation of host immune response and presence of protective antibodies against these surface exposed molecules in patient sera highlights them as attractive targets of antimalarial therapies and vaccines. 2TM proteins are Plasmodium export elements positive, and several of these are exported to the infected erythrocyte surface after exiting through the classical secretory pathway within parasites. Cleaved and modified proteins are trafficked after packaging in vesicles to reach

A new comprehensive index for drought monitoring with TM data

NASA Astrophysics Data System (ADS)

Wang, Yuanyuan

2017-10-01

Drought is one of the most important and frequent natural hazards to agriculture production in North China Plain. To improve agriculture water management, accurate drought monitoring information is needed. This study proposed a method for comprehensive drought monitoring by combining a meteorological index and three satellite drought indices of TM data together. SPI (Standard Precipitation Index), the meteorological drought index, is used to measure precipitation deficiency. Three satellite drought indices (Temperature Vegetation Drought Index, Land Surface Water Index, Modified Perpendicular Drought Index) are used to evaluate agricultural drought risk by exploring data from various channels (VIS, NIR, SWIR, TIR). Considering disparities in data ranges of different drought indices, normalization is implemented before combination. First, SPI is normalized to 0 — 100 given that its normal range is -4 - +4. Then, the three satellite drought indices are normalized to 0 - 100 according to the maximum and minimum values in the image, and aggregated using weighted average method (the result is denoted as ADI, Aggregated drought index). Finally, weighed geometric mean of SPI and ADI are calculated (the result is denoted as DIcombined). A case study in North China plain using three TM images acquired during April-May 2007 show that the method proposed in this study is effective. In spatial domain, DIcombined demonstrates dramatically more details than SPI; in temporal domain, DIcombined shows more reasonable drought development trajectory than satellite indices that are derived from independent TM images.

Selling to NASA

NASA Technical Reports Server (NTRS)

1990-01-01

This handbook is designed to promote a better understanding of NASA's interests and the process of doing business with NASA. The document is divided into the following sections: (1) this is NASA; (2) the procurement process; (3) marketing your capabilities; (4) special assistance programs; (5) NASA field installations; (6) sources of additional help; (7) listing of NASA small/minority business personnel; and (8) NASA organization chart.

Investigation of Tm3+/Yb3+ co-doped germanate-tellurite glasses for efficient 2 µm mid-infrared laser materials

NASA Astrophysics Data System (ADS)

Dou, Aoju; Shen, Lingling; Wang, Ning; Cai, Yangjian; Cai, Muzhi; Guo, Yanyan; Huang, Feifei; Tian, Ying; Xu, Shiqing; Zhang, Junjie

2018-05-01

The Tm3+/Yb3+ co-doped germanate-tellurite glasses with good thermal properties were prepared. Based on the absorption spectra and the Judd-Ofelt theory, the J-O intensity parameters (Ω t ), radiative transition probability (276.78 s- 1), fluorescence lifetime (3.89 ms), absorption and emission cross sections ({σ e} = 1.35 × 10- 20 cm2) were calculated. The 2 µm mid-infrared emission resulting from the 3F4→3H6 transition of Tm3+ sensitized by Yb3+ was observed pumped by 980 nm LD. Besides, the energy transfer mechanism between Yb3+ and Tm3+ was thoroughly discussed. The measured 2 µm emission lifetime of Tm3+/Yb3+ co-doped glass can reach as high as 2.38 ms. The above results showed that Tm3+/Yb3+ co-doping glass could be expected to be a promising material to achieve high efficient 2 µm lasing with a 980 nm LD pumping.

The NASA SCI Files[TM]: The Case of the Powerful Pulleys. A Lesson Guide with Activities in Mathematics, Science, and Technology.

ERIC Educational Resources Information Center

Ricles, Shannon

This teacher's guide, with accompanying videotape, presents an episode of the NASA SCI Files. In this episode, one of the tree house detectives has had an accident and cannot get into the tree house. Using problem-based learning, the rest of the gang investigates the world of simple machines and physical science and "pull" together to…

Effect of GutsyGum(tm), A Novel Gum, on Subjective Ratings of Gastro Esophageal Reflux Following A Refluxogenic Meal.

PubMed

Brown, Rachel; Sam, Cecilia H Y; Green, Tim; Wood, Simon

2015-06-01

Chewing gum alleviates symptoms of gastro-esophageal reflux (GER) following a refluxogenic meal. GutsyGum(tm), a chewing gum developed to alleviate the symptoms of GER contains calcium carbonate, with a proprietary blend of licorice extract, papain, and apple cider vinegar (GiGs®). The efficacy of GutsyGum(tm) was determined in alleviating the symptoms of GER after a refluxogenic meal compared to placebo gum. This double-blind, placebo-controlled-crossover trial with a one-week washout between treatments had 24 participants with a history of GER consume a refluxogenic meal and then chew GutsyGum(tm) or placebo gum. Participants completed GER symptom questionnaires, consisting of symptom based 10 cm Visual Analogue Scales, immediately following the meal and then at regular intervals out to four hours postmeal. Adjusted mean ± SEM heartburn score (15-min postmeal to 240 min) was significantly lower in GutsyGum(tm) than in placebo gum treatment (0.81 ± 0.20 vs. 1.45 ± 0.20 cm; p = 0.034). Mean acid reflux score was significantly lower in GutsyGum(tm) than in placebo treatment (0.72 ± 0.19 vs. 1.46 ± 0.19 cm; p = 0.013). There were no significant differences for any of the secondary outcomes. However, pain approached significance with less pain reported in GutsyGum(tm) versus placebo treatment (0.4 ± 0.2 vs. 0.9 ± 0.2 cm; p = 0.081). Although nausea (p = 0.114) and belching (p = 0.154) were lower following GutsyGum(tm), the difference was not statistically significant. GutsyGum(tm) is more effective than a placebo gum in alleviating primary symptoms of heartburn and acid reflux (Clinical Trial Registration: ACTRN12612000973819).

NASA Social

NASA Image and Video Library

2012-12-04

NASA astronaut Joe Acaba answers questions at a NASA Social at NASA Headquarters on Tuesday, Dec. 4, 2012 in Washington. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

Cleaning Spectralon(TM) To Maintain Reflectance Properties

NASA Technical Reports Server (NTRS)

Stiegman, Albert; Bruegge, Carl; Plett, Gary

1996-01-01

Hydrocarbon impurities removed and stability of Spectralon(TM) towards ultraviolet and vacuum-ultraviolet radiation greatly enhanced by baking material at 90 degrees C for 24 h in vacuum of 10 to negative 5th power torr. After vacuum bake, material handled with white cotton, lint-free gloves in clean environment (preferably cleanroom). As material has tendency to reabsorb volatile organic compounds, stored and transported only in clean, air-tight (preferably glass or oil-free metal) containers.

Retrieval of land cover information under thin fog in Landsat TM image

NASA Astrophysics Data System (ADS)

Wei, Yuchun

2008-04-01

Thin fog, which often appears in remote sensing image of subtropical climate region, has resulted in the low image quantity and bad image mapping. Therefore, it is necessary to develop the image processing method to retrieve land cover information under thin fog. In this paper, the Landsat TM image near the Taihu Lake that is in the subtropical climate zone of China was used as an example, and the workflow and method used to retrieve the land cover information under thin fog have been built based on ENVI software and a single TM image. The basic step covers three parts: 1) isolating the thin fog area in image according to the spectral difference of different bands; 2) retrieving the visible band information of different land cover types under thin fog from the near-infrared bands according to the relationships between near-infrared bands and visible bands of different land cover types in the area without fog; 3) image post-process. The result showed that the method in the paper is easy and suitable, and can be used to improve the quantity of TM image mapping more effectively.

TM9 and cannibalism: how to learn more about cancer by studying amoebae and invertebrates.

PubMed

Fais, Stefano; Fauvarque, Marie-Odile

2012-01-01

Phagocytosis is used not only for immune defense but may also be used to obtain nutrients, as observed when tumor cells feed upon neighboring cells during "tumor cell cannibalism". The TM9 protein TM9SF4, important in canonical phagocytosis, is involved in this cannibalism by metastatic cells and may represent a novel therapeutic target. Copyright © 2011 Elsevier Ltd. All rights reserved.

Diode-Pumped Long-Pulse-Length Ho:Tm:YLiF4 Laser at 10 Hz

NASA Technical Reports Server (NTRS)

Jani, Mahendra G.; Naranjo, Felipe L.; Barnes, Norman P.; Murray, Keith E.; Lockard, George E.

1995-01-01

An optical efficiency of 0.052 under normal mode operation for diode-pumped Ho:Tm:YLiF4 at a pulse repetition frequency of 10 Hz has been achieved. Laser output energy of 30 mJ in single Q-switched pulses with 600-ns pulse length were obtained for an input energy of 3 J. A diffusion-bonded birefringent laser rod consisting of Ho:Tm-doped and undoped pieces of YLF was utilized for 10-Hz operation.

NASA Future Forum

NASA Image and Video Library

2011-08-11

Dr. Laurie Leshin, NASA Deputy Associate Administrator Exploration Systems Mission Directortorate, second from right, speaks as Dr. Waleed Abdalati, NASA Chief Scientist, right, Dr. Robert Braun, NASA Chief Technologist, and Leland Melvin, Assoicate Administrator for NASA Education, far left, at the NASA Future Forum held at the Riggs Alumni Center on the campus of the University of Maryland, Thursday, Aug. 11, 2011 in College Park, Md. Photo Credit: (NASA/Paul E. Alers)

Scaling Users' Perceptions of Library Service Quality Using Item Response Theory: A LibQUAL+ [TM] Study

ERIC Educational Resources Information Center

Wei, Youhua; Thompson, Bruce; Cook, C. Colleen

2005-01-01

LibQUAL+[TM] data to date have not been subjected to the modern measurement theory called polytomous item response theory (IRT). The data interpreted here were collected from 42,090 participants who completed the "American English" version of the 22 core LibQUAL+[TM] items, and 12,552 participants from Australia and Europe who…

NASA Social

NASA Image and Video Library

2012-05-19

NASA Administrator Charles Bolden, left, and Kennedy Space Center director Robert Cabana appear at the NASA Social event, Friday morning, May 19, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

NASA Social

NASA Image and Video Library

2012-12-04

NASA astronaut Joe Acaba speaks at a behind-the-scenes NASA Social at NASA Headquarters on Tuesday, Dec. 4, 2012 in Washington. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

NASA Social

NASA Image and Video Library

2012-12-04

A NASA Social participant tweets during as astronaut Joe Acaba answers questions from the audience at NASA Headquaters, Tuesday, Dec. 4, 2012 in Washington. NASA astronaut Acaba launched to the ISS on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

NASA Social

NASA Image and Video Library

2012-12-04

NASA astronaut Joe Acaba answers questions at a behind-the-scenes NASA Social at NASA Headquarters on Tuesday, Dec. 4, 2012 in Washington. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

NASA Social

NASA Image and Video Library

2012-12-04

NASA astronaut Joe Acaba, center, greets participants at a behind-the-scenes NASA Social in Washington, Tuesday, Dec. 4, 2012 at NASA Headquarters. Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

Cubic to tetragonal phase transition of Tm{sup 3+} doped nanocrystals in oxyfluoride glass ceramics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Yiming; Fu, Yuting; Shi, Yahui

2016-02-15

Tm{sup 3+} ions doped β-PbF{sub 2} nanocrystals in oxyfluoride glass ceramics with different doping concentrations and thermal temperatures are prepared by a traditional melt-quenching and thermal treatment method to investigate the structure and the phase transition of Tm{sup 3+} doped nanocrystals. The structures are characterized by X-ray diffraction Rietveld analysis and confirmed with numerical simulation. The phase transitions are proved further by the emission spectra. Both of the doping concentration and thermal temperature can induce an O{sub h} to D{sub 4h} site symmetry distortion and a cubic to tetragonal phase transition. The luminescence of Tm{sup 3+} doped nanocrystals at 800more » nm was modulated by the phase transition of the surrounding crystal field.« less

Near-IR, blue, and UV generation by frequency conversion of a Tm:YAP laser

NASA Astrophysics Data System (ADS)

Cole, Brian; Goldberg, Lew; Chinn, Steve

2018-02-01

We describe generation of near-infrared (944nm, 970nm), blue (472nm, 485nm), and UV (236 nm) light by frequency up-conversion of 2 μm output of a compact and efficient passively Q-switched Tm:YAP laser. The Tm:YAP laser source was near diffraction limited with maximum Q-switched pulse peak power of 190 kW. For second harmonic generation (SHG) of NIR, both periodically poled lithium niobate (PPLN) and lithium tri-borate (LBO) were evaluated, with 58% conversion efficiency and 3.1 W of 970 nm power achieved with PPLN. The PPLN 970nm emission was frequency doubled in 20mm long type I LBO, generating 1.1 W at 485nm with a conversion efficiency of 34%. With LBO used for frequency doubling of 2.3 W of 1888 nm Tm:YAP output to 944nm, 860mW was generated, with 37% conversion efficiency. Using a second LBO crystal to generate the 4th harmonic, 545mW of 472nm power was generated, corresponding to 64% conversion efficiency. To generate the 8th harmonic of Tm:YAP laser emission, the 472nm output of the second LBO was frequency doubled in a 7mm long BBO crystal, generating 110 mW at 236nm, corresponding to 21% conversion efficiency.

GPS PPP-derived precipitable water vapor retrieval based on Tm/Ps from multiple sources of meteorological data sets in China

NASA Astrophysics Data System (ADS)

Zhang, Hongxing; Yuan, Yunbin; Li, Wei; Ou, Jikun; Li, Ying; Zhang, Baocheng

2017-04-01

Weighted mean temperature (Tm) and pressure (Ps) are two parameters of great relevance to precipitable water vapor (PWV) retrieval from global positioning system (GPS) data. However, information about the Tm and Ps cannot be available for those GPS stations that are not colocated with meteorological sensors. To investigate the optimal GPS-PWV retrieval method for China, two enhanced Tm models, GM-Tm (temperature dependent) and GH-Tm (temperature independent), are developed. Additionally, the potentials of the Ps data from the two reanalysis data sets, the National Centers for Environmental Prediction (NCEP)-Department of Energy (DOE) Reanalysis II (NCEP II) and ERA-Interim, and from the empirical model GPT2w for GPS-PWV retrieval are investigated over China. To evaluate the performances of multisources Tm and Ps data for GPS-PWV retrieval, GPS data (2011-2013) collected from 22 stations of the Crustal Movement Observation Network of China (CMONOC) were processed by using the precise point positioning (PPP) technique, estimating the zenith tropospheric delay (ZTD) so as to be subsequently converted to GPS-PWV. The retrieved GPS-PWVs are compared with their counterparts derived from NCEP II and radiosonde data over China. The results show that (1) the GM-Tm model consistently shows the highest accuracy (with root mean square error of 2.3 K), and the GH-Tm model should be selected when temperature observations are not available, and that (2) the performances of Ps from NCEP II and ERA-Interim differ marginally for GPS-PWV retrieval, and significant seasonal variations are found in the agreement between the GPS-PWVs and the PWVs derived from NCEP II and radiosonde data over China.

White up-conversion emission in Ho3+/Tm3+/Yb3+ tri-doped glass ceramics embedding BaF2 nanocrystals

NASA Astrophysics Data System (ADS)

Li, Chenxia; Xu, Shiqing; Ye, Rengguang; Deng, Degang; Hua, Youjie; Zhao, Shilong; Zhuang, Songlin

2011-04-01

Ho3+/Tm3+/Yb3+ tri-doped glass ceramics with white light emitting have been developed and demonstrated. Pumped by 980 nm laser diode (LD), intensive red, green and blue up-conversions (UC) were obtained. The green emission is assigned to Ho3+ ion and the blue emission is assigned to Tm3+ ion, whereas the red emission is the combination contribution of the Ho3+ and Tm3+ ions. The RGB intensities could be adjusted by tuning the rare-earth ion concentration and pump power intensity. Thus, multicolor of the luminescence, including perfect white light with CIE-X=0.329 and CIE-Y=0.342 in the 1931 CIE chromaticity diagram can be obtained in 0.15 Ho3+/0.2Tm3+/3Yb3+ tri-doped glass ceramics embedding BaF2 nanocrystals pumped by a single infrared laser diode source of 980 nm at 500 mW. The up-conversion luminescence mechanism of Yb3+ sensitize Ho3+ and Tm3+ ions and the energy transfer from Ho3+ to Tm3+ in oxy-fluoride silicate glass ceramics were analyzed.

Words Their Way[TM]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2013

2013-01-01

"Words Their Way"[TM] is an approach to phonics, vocabulary, and spelling instruction for students in kindergarten through high school. The program can be implemented as a core or supplemental curriculum and aims to provide a practical way to study words with students. The purpose of word study (which involves examining, manipulating,…

Expression of TM4SF10, a Claudin/EMP/PMP22 family cell junction protein, during mouse kidney development and podocyte differentiation.

PubMed

Bruggeman, Leslie A; Martinka, Scott; Simske, Jeffrey S

2007-02-01

Cell junctions in the nephron are highly specialized to perform specific and distinct filtration and reabsorption functions. The mature kidney forms complex cell junctions including slit diaphragms that prevent the passage of serum proteins into the filtrate, and tubule cell junctions that regulate specific paracellular ion reuptake. We have investigated the expression of TM4SF10 (Trans-Membrane tetra(4)-Span Family 10) in mouse kidneys. TM4SF10 is the vertebrate orthologue of Caenorhabditis elegans VAB-9, a tetraspan adherens junction protein in the PMP22/EMP/Claudin family of proteins. We found that TM4SF10 localizes at the basal-most region of podocyte precursors before the capillary loop stage, at some tubule precursors, and at the ureteric bud junction with S-shaped bodies. Overall expression of TM4SF10 peaked at postnatal day 4 and was virtually absent in adult kidneys. The very limited expression of TM4SF10 protein that persisted into adulthood was restricted to a few tubule segments but remained localized to the basal region of lateral membranes. In undifferentiated cultured podocytes, TM4SF10 localized to the perinuclear region and translocated to the cell membrane after Cadherin appearance at cell-cell contacts. TM4SF10 colocalized with ZO1 and p120ctn in undifferentiated confluent podocytes and also colocalized with the tips of actin filaments at cell contacts. Upon differentiation of cultured podocytes, TM4SF10 protein disappeared from cell contacts and expression ceased. These results suggest that TM4SF10 functions during differentiation of podocytes and may participate in the maturation of cell junctions from simple adherens junctions to elaborate slit diaphragms. TM4SF10 may define a new class of Claudin-like proteins that function during junctional development.

Neutron Scattering Cross Section Measurements for 169Tm via the (n,n') Technique

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alimeti, Afrim; Kegel, Gunter H.R.; Egan, James J.

2005-05-24

The neutron physics group at the University of Massachusetts Lowell (UML) has been involved in a program of scattering cross-section measurements for highly deformed nuclei such as 159Tb, 169Tm, 232Th, 235U, 238U, and 239Pu. Ko et al. have reported neutron inelastic scattering data from 169Tm for states above 100 keV via the (n,n'{gamma}) reaction at incident energies in the 0.2 MeV to 1.0 MeV range. In the present research, in which the time-of-flight method was employed, direct (n,n') measurements of neutrons scattered from 169Tm in the 0.2 to 1.0 MeV range were taken. It requires that our 5.5-MeV Van demore » Graaff accelerator be operated in the pulsed and bunched beam mode producing subnanosecond pulses at a 5-MHz repetition frequency. Neutrons are produced by the 7Li(p,n)7Be reaction using a thin metallic elemental lithium target.« less

Rigorous theory of the diffraction of Gaussian beams by finite gratings: TM polarization.

PubMed

Mata-Mendez, O; Avendaño, J; Chavez-Rivas, F

2006-08-01

Diffraction of TM-polarized Gaussian beams by N equally spaced slits (finite grating) in a planar perfectly conducting thick screen is treated. We extend to the TM polarization case the results of a previous paper where the TE polarization was considered. The far-field diffraction patterns, the transmission coefficient tau, and the normally diffracted energy E as a function of several optogeometrical parameters are analyzed within the so-called vectorial region. The existence of constant-intensity angles in the far field when the incident beam wave is scanned along the N slits is shown. In addition, the property E=Ntau/lambda, valid in the scalar region, is extended to the TM polarization case in the vectorial region, lambda being the wavelength. The coupling between slits is analyzed, giving an oscillating amplitude-decreasing function as the separation between slits increases, where the period for these oscillations is the wavelength lambda. Finally, the extraordinary optical transmission phenomena that appear when the wavelength is larger than the slit width (subwavelength regime) are analyzed.

Analysis of differentially regulated proteins in TM4 cells treated with bisphenol A.

PubMed

Lee, Do-Youn; Lee, Sang-Soo; Joo, Won-A; Lee, Eun-Ju; Kim, Chan-Wha

2004-06-01

BPA, bisphenol A, a monomer of epoxy resins and polycarbonate plastic, is used in many consumer products including the plastic linings of cans for food and babies' bottles. BPA has been reported to cause reproductive toxicity and affects cells in rats and mice at high doses. In this study, the effect of BPA on protein expression in TM4 cells (a mouse Sertoli cell line) known to play an essential role in Spermatogenesis was investigated by two-dimensional electrophoresis (2-DE). After 16 h exposure to 50, 100, 150, 200, and 250 microM of BPA, the viability of TM4 cells decreased to about 90, 85, 78, 55, and 30% of control respectively. Approximately 800 protein spots in TM4 cells were analyzed by 2-DE with pH 4-7 linear immobilized pH gradient (IPG) Dry Strip, and 11 proteins which showed significantly different expression levels were identified by matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS). Among these, HSP 27 and placental calcium binding protein may be proteins differentially expressed by BPA exposure.

NASA Future Forum

NASA Image and Video Library

2011-08-11

Dr. Robert Braun, NASA Chief Technologist, second from left, makes a point, as panelists Leland Melvin, Assoicate Administrator for NASA Education, left, Dr. Laurie Leshin, NASA Deputy Associate Administrator Exploration Systems Mission Directortorate, and Dr. Waleed Abdalati, NASA Chief Scientist, right, look on during a panel discussion at the NASA Future Forum held at the Riggs Alumni Center on the campus of the University of Maryland, Thursday, Aug. 11, 2011 in College Park, Md. Photo Credit: (NASA/Paul E. Alers)

Synthesis and Characterization of Monodisperse Core-shell Lanthanide Upconversion Nanoparticles NaYF4: Yb,Tm/SiO2

NASA Astrophysics Data System (ADS)

Manurung, R. V.; Wiranto, G.; Hermida, I. D. P.

2018-05-01

Lanthanide up-converting luminescent nanoparticles (UCNPs) are exciting and promising materials for optical bioimaging, biosensor and theranostic due to their unique and advantageous optical and chemical properties. The UCNPs absorb low energy near-infrared (NIR) light and emit high-energy shorter wavelength photons (visible light). Their unique features allow them to overcome various problems associated with conventional imaging probes such as photostability, lack of toxicity, and to provide versatility for creating nanoplatforms with both imaging and therapeutic modalities. This paper reports synthesis and characterization of core-shell structured of NaYF4:Yb,Tm/SiO2 microspheres. The synthesis of lanthanide upconversion nanoparticles NaYF4:Yb,Tm was prepared by thermal decomposition process which involves dissolving organic precursors in high-boiling-point solvents oleic acid (OA) and octadecene (ODE). After that, the NaYF4:Yb,Tm phosphors was coated by silica via reverse microemulsion process to obtain core-shell structured NaYF4:Yb,Tm/SiO2. Scanning electron microscopy, transmission electron microscopy, specific area electron diffraction, and photoluminescence were applied to characterize these samples. The obtained core-shell structured NaYF4:Yb,Tm/SiO2 phosphors exhibit a perfect cubic morphology with narrow size distribution and smooth surface. Upon IR excitation at 980 nm, the NaYF4:Yb,Tm/SiO2 samples exhibit whitish blue upconversion (UC) luminescence, respectively. These phosphors show potential applications in the displaying on biological fields and biosensing.

High-power ultralong-wavelength Tm-doped silica fiber laser cladding-pumped with a random distributed feedback fiber laser

PubMed Central

Jin, Xiaoxi; Du, Xueyuan; Wang, Xiong; Zhou, Pu; Zhang, Hanwei; Wang, Xiaolin; Liu, Zejin

2016-01-01

We demonstrated a high-power ultralong-wavelength Tm-doped silica fiber laser operating at 2153 nm with the output power exceeding 18 W and the slope efficiency of 25.5%. A random distributed feedback fiber laser with the center wavelength of 1173 nm was employed as pump source of Tm-doped fiber laser for the first time. No amplified spontaneous emissions or parasitic oscillations were observed when the maximum output power reached, which indicates that employing 1173 nm random distributed feedback fiber laser as pump laser is a feasible and promising scheme to achieve high-power emission of long-wavelength Tm-doped fiber laser. The output power of this Tm-doped fiber laser could be further improved by optimizing the length of active fiber, reflectivity of FBGs, increasing optical efficiency of pump laser and using better temperature management. We also compared the operation of 2153 nm Tm-doped fiber lasers pumped with 793 nm laser diodes, and the maximum output powers were limited to ~2 W by strong amplified spontaneous emission and parasitic oscillation in the range of 1900–2000 nm. PMID:27416893

High-power ultralong-wavelength Tm-doped silica fiber laser cladding-pumped with a random distributed feedback fiber laser.

PubMed

Jin, Xiaoxi; Du, Xueyuan; Wang, Xiong; Zhou, Pu; Zhang, Hanwei; Wang, Xiaolin; Liu, Zejin

2016-07-15

We demonstrated a high-power ultralong-wavelength Tm-doped silica fiber laser operating at 2153 nm with the output power exceeding 18 W and the slope efficiency of 25.5%. A random distributed feedback fiber laser with the center wavelength of 1173 nm was employed as pump source of Tm-doped fiber laser for the first time. No amplified spontaneous emissions or parasitic oscillations were observed when the maximum output power reached, which indicates that employing 1173 nm random distributed feedback fiber laser as pump laser is a feasible and promising scheme to achieve high-power emission of long-wavelength Tm-doped fiber laser. The output power of this Tm-doped fiber laser could be further improved by optimizing the length of active fiber, reflectivity of FBGs, increasing optical efficiency of pump laser and using better temperature management. We also compared the operation of 2153 nm Tm-doped fiber lasers pumped with 793 nm laser diodes, and the maximum output powers were limited to ~2 W by strong amplified spontaneous emission and parasitic oscillation in the range of 1900-2000 nm.

Index matching of TE and TM modes in organic multilayer waveguides

NASA Astrophysics Data System (ADS)

Thompson, Jonathan; Schmitzer, Heidrun; Wagner, Hans Peter

We investigate transverse electric (TE) and magnetic (TM) mode propagation in organic multilayers consisting of aluminum quinoline (Alq3) and perylenetetracarboxylic dianhydride (PTCDA). In particular, we analyze two multilayer waveguides, Alq3-PTCDA-Alq3 and PTCDA-Alq3-PTCDA, engineered to give index matching according to modeling. The waveguides were grown on a glass substrate via organic molecular beam deposition. Fabry-Perot oscillations observed from reflection measurements were used to confirm the individual layer thicknesses. We were able to observe refractive index matching between TE0 and TE1, as well as TE2 and TE3 modes for the PTCDA-Alq3-PTCDA waveguide due to the light propagation through the top and bottom PTCDA layers, respectively. In addition, we were able to match TE1 and TM1, as well as TE3 and TM3 modes in the Alq3-PTCDA-Alq3 multilayer due to the birefringence of the PTCDA layer. Furthermore, we are able to create mode matching for a range of wavelengths due to the similar effective refractive index dispersion of different waveguide modes. The ability to phase match different waveguide modes opens a wide range of potential applications including polarization-insensitive propagation and mode switching by adding a thin magnetic metal film within the waveguide and applying an external magnetic field.

High efficiency 2 micrometer laser utilizing wing-pumped Tm.sup.3+ and a laser diode array end-pumping architecture

DOEpatents

Beach, Raymond J.

1997-01-01

Wing pumping a Tm.sup.3+ doped, end pumped solid state laser generates 2 .mu.m laser radiation at high average powers with high efficiency. Using laser diode arrays to end-pump the laser rod or slab in the wing of the Tm.sup.3+ absorption band near 785 nm results in 2-for-1 quantum efficiency in Tm.sup.3+ because high Tm.sup.3+ concentrations can be used. Wing pumping allows the thermal power generated in the rod or slab to be distributed over a large enough volume to make thermal management practical in the laser gain medium even at high average power operation. The approach is applicable to CW, Q-switched, and rep-pulsed free-laser operation.

High efficiency 2 micrometer laser utilizing wing-pumped Tm{sup 3+} and a laser diode array end-pumping architecture

DOEpatents

Beach, R.J.

1997-11-18

Wing pumping a Tm{sup 3+} doped, end pumped solid state laser generates 2 {micro}m laser radiation at high average powers with high efficiency. Using laser diode arrays to end-pump the laser rod or slab in the wing of the Tm{sup 3+} absorption band near 785 nm results in 2-for-1 quantum efficiency in Tm{sup 3+} because high Tm{sup 3+} concentrations can be used. Wing pumping allows the thermal power generated in the rod or slab to be distributed over a large enough volume to make thermal management practical in the laser gain medium even at high average power operation. The approach is applicable to CW, Q-switched, and rep-pulsed free-laser operation. 7 figs.

NASA Social

NASA Image and Video Library

2012-12-04

A participant at a NASA Social in Washington engages in social media as he listens to astronaut Joe Acaba answer questions, Tuesday, Dec. 4, 2012 at NASA Headquarters. NASA astronaut Joe Acaba launched to the International Space Station on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

NASA Social

NASA Image and Video Library

2012-12-04

A participant at a NASA Social in Washington listens to astronaut Joe Acaba answer questions about his time living aboard the International Space Station, Tuesday, Dec. 4, 2012 at NASA Headquarters. NASA astronaut Acaba launched to the ISS on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

ISS NASA Social

NASA Image and Video Library

2013-02-20

NASA Astronaut Don Pettit, speaks about his experience onboard the International Space Station at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

Characteristics of "Tween" Participants and Non-Participants in the VERB[TM] Summer Scorecard Physical Activity Promotion Program

ERIC Educational Resources Information Center

Nickelson, Jen; Alfonso, Moya L.; McDermott, Robert J.; Bumpus, Elizabeth C.; Bryant, Carol A.; Baldwin, Julie A.

2011-01-01

Creating community-based opportunities for youth to be physically active is challenging for many municipalities. A Lexington, Kentucky community coalition designed and piloted a physical activity program, "VERB[TM] summer scorecard (VSS)", leveraging the brand equity of the national VERB[TM]--It's What You Do! campaign. Key elements of…

NASA Astrophysics Technology Needs

NASA Technical Reports Server (NTRS)

Stahl, H. Philip

2012-01-01

July 2010, NASA Office of Chief Technologist (OCT) initiated an activity to create and maintain a NASA integrated roadmap for 15 key technology areas which recommend an overall technology investment strategy and prioritize NASA?s technology programs to meet NASA?s strategic goals. Science Instruments, Observatories and Sensor Systems(SIOSS) roadmap addresses technology needs to achieve NASA?s highest priority objectives -- not only for the Science Mission Directorate (SMD), but for all of NASA.

Ultra-compact resonant tunneling-based TE-pass and TM-pass polarizers for SOI platform.

PubMed

Azzam, Shaimaa I; Obayya, Salah S A

2015-03-15

We investigate the polarization-dependent resonance tunneling effect in silicon waveguides to achieve ultra-compact and highly efficient polarization fitters for integrated silicon photonics, to the best of our knowledge for the first time. We hence propose simple structures for silicon-on-insulator transverse electric (TE)-pass and transverse magnetic (TM)-pass polarizers based on the resonance tunneling effect in silicon waveguides. The suggested TE-pass polarizer has insertion losses (IL), extinction ratio (ER), and return losses (RL) of 0.004 dB, 18 dB, and 24 dB, respectively; whereas, the TM-pass polarizer is characterized by IL, ER, and RL of 0.15 dB, 20 dB, and 23 dB, respectively. Both polarizers have an ultra-short device length of only 1.35 and 1.31 μm for the TE-pass and the TM-pass polarizers which are the shortest reported lengths to the best of our knowledge.

NPOESS C3S Expandability: SafetyNet(TM) and McMurdo Improvements

NASA Astrophysics Data System (ADS)

Paciaroni, J.; Jamilkowski, M. L.

2009-12-01

The National Oceanic & Atmospheric Administration (NOAA), Department of Defense (DoD), and National Aeronautics and Space Administration (NASA) are jointly acquiring the next-generation weather and environmental satellite system; the National Polar-orbiting Operational Environmental Satellite System (NPOESS). NPOESS replaces the current Polar-orbiting Operational Environmental Satellites (POES) managed by NOAA and the Defense Meteorological Satellite Program (DMSP) managed by the DoD. The NPOESS satellites carry a suite of sensors that collect meteorological, oceanographic, climatological, and solar-geophysical observations of the earth, atmosphere, and space. The command and telemetry portion of NPOESS is the Command, Control and Communications Segment (C3S), developed by Raytheon Intelligence & Information Systems. C3S is responsible for managing the overall NPOESS mission from control and status of the space and ground assets to ensuring delivery of timely, high quality data from the Space Segment (SS) to the Interface Data Processing Segment (IDPS) for processing. In addition, the C3S provides the globally distributed ground assets necessary to collect and transport mission, telemetry, and command data between the satellites and the processing locations. The C3S provides all functions required for day-to-day commanding and state-of-health monitoring of the NPP and NPOESS satellites, and delivery of Stored Mission Data (SMD) to each U.S. Weather Central Interface Data Processor (IDP) for data products development and transfer to System subscribers. The C3S also monitors and reports system-wide health and status and data communications with external systems and between the NPOESS segments. Two crucial elements of NPOESS C3S expandability are SafetyNet(TM) and communications improvements to McMurdo Station, Antarctica. ‘SafetyNet(TM)’ is a key feature of the National Polar-orbiting Operational Environmental Satellite System (NPOESS), vital element of the C3S

NASA Social

NASA Image and Video Library

2012-12-04

A participant at a NASA Social in Washington tweets as he listens to astronaut Joe Acaba answer questions about his time living aboard the International Space Station, Tuesday, Dec. 4, 2012 at NASA Headquarters. NASA astronaut Joe Acaba launched to the ISS on a Russian Soyuz spacecraft May 15, 2012, spending 123 days aboard as a flight engineer of the Expedition 31 and 32 crews. He recently returned to Earth on Sept. 17 after four months in low earth orbit. Photo Credit: (NASA/Carla Cioffi)

Axenic Culture of a Candidate Division TM7 Bacterium from the Human Oral Cavity and Biofilm Interactions with Other Oral Bacteria

PubMed Central

Soro, Valeria; Dutton, Lindsay C.; Sprague, Susan V.; Nobbs, Angela H.; Ireland, Anthony J.; Sandy, Jonathan R.; Jepson, Mark A.; Micaroni, Massimo; Splatt, Peter R.; Dymock, David

2014-01-01

The diversity of bacterial species in the human oral cavity is well recognized, but a high proportion of them are presently uncultivable. Candidate division TM7 bacteria are almost always detected in metagenomic studies but have not yet been cultivated. In this paper, we identified candidate division TM7 bacterial phylotypes in mature plaque samples from around orthodontic bonds in subjects undergoing orthodontic treatment. Successive rounds of enrichment in laboratory media led to the isolation of a pure culture of one of these candidate division TM7 phylotypes. The bacteria formed filaments of 20 to 200 μm in length within agar plate colonies and in monospecies biofilms on salivary pellicle and exhibited some unusual morphological characteristics by transmission electron microscopy, including a trilaminated cell surface layer and dense cytoplasmic deposits. Proteomic analyses of cell wall protein extracts identified abundant polypeptides predicted from the TM7 partial genomic sequence. Pleiomorphic phenotypes were observed when the candidate division TM7 bacterium was grown in dual-species biofilms with representatives of six different oral bacterial genera. The TM7 bacterium formed long filaments in dual-species biofilm communities with Actinomyces oris or Fusobacterium nucleatum. However, the TM7 isolate grew as short rods or cocci in dual-species biofilms with Porphyromonas gingivalis, Prevotella intermedia, Parvimonas micra, or Streptococcus gordonii, forming notably robust biofilms with the latter two species. The ability to cultivate TM7 axenically should majorly advance understanding of the physiology, genetics, and virulence properties of this novel candidate division oral bacterium. PMID:25107981

Axenic culture of a candidate division TM7 bacterium from the human oral cavity and biofilm interactions with other oral bacteria.

PubMed

Soro, Valeria; Dutton, Lindsay C; Sprague, Susan V; Nobbs, Angela H; Ireland, Anthony J; Sandy, Jonathan R; Jepson, Mark A; Micaroni, Massimo; Splatt, Peter R; Dymock, David; Jenkinson, Howard F

2014-10-01

The diversity of bacterial species in the human oral cavity is well recognized, but a high proportion of them are presently uncultivable. Candidate division TM7 bacteria are almost always detected in metagenomic studies but have not yet been cultivated. In this paper, we identified candidate division TM7 bacterial phylotypes in mature plaque samples from around orthodontic bonds in subjects undergoing orthodontic treatment. Successive rounds of enrichment in laboratory media led to the isolation of a pure culture of one of these candidate division TM7 phylotypes. The bacteria formed filaments of 20 to 200 μm in length within agar plate colonies and in monospecies biofilms on salivary pellicle and exhibited some unusual morphological characteristics by transmission electron microscopy, including a trilaminated cell surface layer and dense cytoplasmic deposits. Proteomic analyses of cell wall protein extracts identified abundant polypeptides predicted from the TM7 partial genomic sequence. Pleiomorphic phenotypes were observed when the candidate division TM7 bacterium was grown in dual-species biofilms with representatives of six different oral bacterial genera. The TM7 bacterium formed long filaments in dual-species biofilm communities with Actinomyces oris or Fusobacterium nucleatum. However, the TM7 isolate grew as short rods or cocci in dual-species biofilms with Porphyromonas gingivalis, Prevotella intermedia, Parvimonas micra, or Streptococcus gordonii, forming notably robust biofilms with the latter two species. The ability to cultivate TM7 axenically should majorly advance understanding of the physiology, genetics, and virulence properties of this novel candidate division oral bacterium. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Short-Term Safety and Efficacy of Femoral Vascular Closure after Percutaneous Coronary Intervention with Combination of the Boomerang(TM) Device and Intravenous Protamine Sulfate.

PubMed

Chen, Ching-Pei; Huang, Huang-Kai; Hsia, Chien-Hsun; Chang, Yung-Ming; Lin, Lee-Shin; Lee, Cheng-Liang

2013-11-01

The Cardiva Boomerang(TM) is a device used to perform femoral vascular closure. It facilitates passive hemostasis at the arteriotomy site, leaving no residual foreign body. We performed a controlled, randomized study of 60 patients undergoing percutaneous coronary intervention. Patients were randomized into two groups (30 per group) to undergo vascular closure with the Boomerang(TM) or the Perclose(TM) suture-based device after the intravenous administration of protamine sulfate. We compared overall success rates, patient-reported pain, length of time to achieve hemostasis and mobilization of the patient, and the frequency of complications in the two groups. Overall success rates using the Boomerang(TM) and Perclose(TM) devices were similarly high, at 93% and 97%, respectively. The Boomerang(TM) was significantly quicker to deploy than the PercloseTM, device deployment time, median (Q1-Q3), [2.00 (1.33-2.75) vs. 3.84 (2.75-4.38) mins, p < 0.001)]. The pain score was significantly lower in the Boomerang(TM) group (1.1 ± 1.7 vs. 6.4 ± 2.9, p < 0.001). The time the device remained in the artery and manual compression time were significantly longer with the Boomerang(TM) (p < 0.001), as well as the time taken to achieve hemostasis and time to ambulation. There were no major complications in either group and no significant differences between the groups in the frequency of minor complications. We conclude that when used in combination with intravenous protamine sulfate, the Boomerang(TM) device is as safe and effective as the Perclose(TM) device for femoral vascular closure, but quicker to deploy and less painful to patients. Boomerang; Percutaneous intervention; Vascular closure device.

Fabrication of NIR-responsive NaYF4:Yb,Tm/anatase TiO2 composite aerogel

NASA Astrophysics Data System (ADS)

Li, Fu-Chih; Kitamoto, Yoshitaka

2018-01-01

3-dimensional interconnected network structure of TiO2 aerogel has attracted considerable attention to solve environmental issues due to an advanced oxidation process which uses abundant sunlight for the complete minimization of toxic pollutants. The TiO2 aerogel with high specific surface area, large pores, and low density has a potential to be used as photocatalyst for air and water purification. Nonetheless, due to the larger band gap, TiO2 semiconductor photocatalysts possess high oxidizing properties under UV light only which occupies 5% of solar energy. To expand the absorption spectrum of TiO2 aerogel under solar irradiation, the NaYF4:Yb,Tm nanoparticles (NPs) are introduced into the TiO2 aerogel matrix structure. The morphology and crystal structure of the composite aerogel are investigated by transmission electron microscopy and X-ray diffraction, respectively. The particle size of NaYF4:Yb,Tm NPs is approximately 40 nm and the crystallite size of TiO2 is around 10 nm. In addition, the NaYF4:Yb,Tm NPs are enclosed by anatase phase of TiO2 aerogel. The NaYF4:Yb,Tm NPs which exist in the TiO2 aerogel has a capability of transferring NIR light to UV region.

Linkage studies on 13 biochemical loci and 2 coat color loci in a [(BN x TM) x TM] backcross progeny of the rat (Rattus norvegicus).

PubMed

Yamada, J; Hamada, S; Bender, K; Adams, M

1986-10-01

In a [(BN X TM) X TM] backcross progeny of rats, nine significant linkage associations were found among 105 pairwise combinations of 15 loci. After comparing this with other published data and data of personal communications, we considered that the d gene we tentatively designated may be identical to the gene for pink-eyed dilution (p), and that the associations of Gc-Hbb, RT1-h, and Gc-Fh were due to chance rather than real linkage. The linkages obtained in this study, therefore, were Hbb-p (26.5 +/- 5.5) in LG I, Mup-1-Acon-1 (12.5 +/- 4.1) in LG II, Hao-1-Svp-1 (23.8 +/- 6.6) in LG IV, Es-1-Es-3 (17.2 +/- 4.7) in LG V, h-Gc (10.9 +/- 3.3) in LG VI, and Fh-Pep-3 (32.3 +/- 5.9) in LG X.

NASA historical data book. Volume 4: NASA resources 1969-1978

NASA Technical Reports Server (NTRS)

Gawdiak, Ihor Y.; Fedor, Helen

1994-01-01

This is Volume 4, NASA Resources 1969-1978, of a series providing a 20-year statistical summary of NASA programs. This series is an important component of NASA published historical reference works, used by NASA personnel, managers, external researchers, and other government agencies. This volume combines statistical data of the component facilities with the data of the parent installation.

NASA historical data book. Volume 1: NASA resources 1958-1968

NASA Technical Reports Server (NTRS)

Vannimmen, Jane; Bruno, Leonard C.; Rosholt, Robert L.

1988-01-01

This is Volume 1, NASA Resources 1958-1968, of a multi-volume series providing a 20-year compilation of summary statistical and other data descriptive of NASA's programs in aeronautics and manned and unmanned spaceflight. This series is an important component of NASA published historical reference works, used by NASA personnel, managers, external researchers, and other government agencies.

Probing structure, thermochemistry, electron affinity, and magnetic moment of thulium-doped silicon clusters TmSi n (n = 3-10) and their anions with density functional theory.

PubMed

Huang, Xintao; Yang, Jucai

2017-12-26

The most stable structures and electronic properties of TmSi n (n = 3-10) clusters and their anions have been probed by using the ABCluster global search technique combined with the PBE, TPSSh, and B3LYP density functional methods. The results revealed that the most stable structures of neutral TmSi n and their anions can be regarded as substituting a Si atom of the ground state structure of Si n + 1 with a Tm atom. The reliable AEAs, VDEs and simulated PES of TmSi n (n = 3-10) are presented. Calculations of HOMO-LUMO gap revealed that introducing Tm atom to Si cluster can improve photochemical reactivity of the cluster. The NPA analyses indicated that the 4f electron of Tm atom in TmSi n (n = 3-10) and their anions do not participate in bonding. The total magnetic moments of TmSi n are mainly provided by the 4f electrons of Tm atom. The dissociation energy of Tm atom from the most stable structure of TmSi n and their anions has been calculated to examine relative stability.

2  μm laser oscillation of Ho3+:Tm3+-codoped silica microspheres.

PubMed

Peng, Longxiang; Huang, Yantang; Duan, Yafan; Zhuang, Shijian; Liao, Tingdi; Xu, Canhua

2017-09-10

2 μm laser oscillation with a low threshold has been achieved in Ho 3+ :Tm 3+ -codoped silica microspheres (HTCSMs). Ho 3+ :Tm 3+ -codoped solgel functionalization film is applied to the surface of a silica microsphere, and an optical tapered fiber is adopted to couple an 808 nm continuous-wave laser to serve as the pump light source. Multimode and single-mode laser oscillations around 2 μm within the eye-safe wave band are observed due to the I 7 5→I 8 5 transitions of Ho 3+ ions sensitized by Tm 3+ . The morphology characteristics of microspheres determine the multimode laser oscillation spectrum. The free spectral range is in good accordance with the calculated value based on Mie scattering theory. The HTCSM laser oscillation shows characteristics of good capability, simple process, high flexibility, and low cost.

High beam quality of a Q-switched 2-µm Tm,Ho:LuVO4 laser

NASA Astrophysics Data System (ADS)

Wang, Wei; Yang, Xining; Shen, Yingjie; Li, Linjun; Zhou, Long; Yang, Yuqiang; Bai, Yunfeng; Xie, Wenqiang; Ye, Guangchao; Yu, Xiaoyang

2018-05-01

A diode-end-pumped 2.05-µm Q-switched Tm,Ho:LuVO4 laser is reported in this paper. The cryogenic Tm3+ (5.0 at.%),Ho3+ (0.5 at.%):LuVO4 crystal was pumped by an 800-nm laser diode. At a pulse repetition frequency of 10 kHz, the maximum average output power of 3.77 W was achieved at 77 K when an incident pump power of 14.7 W was used. The slope efficiency and optical-optical conversion efficiency were 28.3 and 25.6%, respectively. The maximum per pulse energy was 2.54 mJ for a pulse duration of 69.9 ns. The beam quality factor Mx 2 was approximately 1.17 and My 2 was approximately 1.01 for the Tm,Ho:LuVO4 laser.

TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet content

PubMed Central

Mahdessian, Hovsep; Taxiarchis, Apostolos; Popov, Sergej; Silveira, Angela; Franco-Cereceda, Anders; Hamsten, Anders; Eriksson, Per; van't Hooft, Ferdinand

2014-01-01

Genome-wide association studies have identified a locus on chromosome 19 associated with plasma triglyceride (TG) concentration and nonalcoholic fatty liver disease. However, the identity and functional role of the gene(s) responsible for these associations remain unknown. Of 19 expressed genes contained in this locus, none has previously been implicated in lipid metabolism. We performed gene expression studies and expression quantitative trait locus analysis in 206 human liver samples to identify the putative causal gene. Transmembrane 6 superfamily member 2 (TM6SF2), a gene with hitherto unknown function, expressed predominantly in liver and intestine, was identified as the putative causal gene. TM6SF2 encodes a protein of 351 amino acids with 7–10 predicted transmembrane domains. Otherwise, no other protein features were identified which could help to elucidate the function of TM6SF2. Protein subcellular localization studies with confocal microscopy demonstrated that TM6SF2 is localized in the endoplasmic reticulum and the ER-Golgi intermediate compartment of human liver cells. Functional studies for secretion of TG-rich lipoproteins (TRLs) and lipid droplet content were performed in human hepatoma Huh7 and HepG2 cells using confocal microscopy and siRNA inhibition and overexpression techniques. In agreement with the genome-wide association data, it was found that TM6SF2 siRNA inhibition was associated with reduced secretion of TRLs and increased cellular TG concentration and lipid droplet content, whereas TM6SF2 overexpression reduced liver cell steatosis. We conclude that TM6SF2 is a regulator of liver fat metabolism with opposing effects on the secretion of TRLs and hepatic lipid droplet content. PMID:24927523

Diode-pumped continuous wave tunable and graphene Q-switched Tm:LSO lasers.

PubMed

Feng, T L; Zhao, S Z; Yang, K J; Li, G Q; Li, D C; Zhao, J; Qiao, W C; Hou, J; Yang, Y; He, J L; Zheng, L H; Wang, Q G; Xu, X D; Su, L B; Xu, J

2013-10-21

We have investigated the lasing characteristics of Tm:LSO crystal in three operation regimes: continuous wave (CW), wavelength tunable and passive Q-switching based on graphene. In CW regime, a maximum output power of 0.65 W at 2054.9 nm with a slope efficiency of 21% was achieved. With a quartz plate, a broad wavelength tunable range of 145 nm was obtained, corresponding to a FWHM of 100 nm. By using a graphene saturable absorber mirror, the passively Q-switched Tm:LSO laser produced pulses with duration of 7.8 μs at 2030.8 nm under a repetition rate of 7.6 kHz, corresponding to pulse energy of 14.0 μJ.

Luminescence of Er/Yb and Tm/Yb doped FAp nanoparticles and ceramics

NASA Astrophysics Data System (ADS)

Grigorjeva, L.; Smits, K.; Millers, D.; Jankoviča, Dz

2015-03-01

The nanoparticles of hydroxiapatite and fluorapatite doped with Er/Yb and Tm/Yb were synthesized and characterized by FTIR, XRD, SEM and TEM methods. The results of up-conversion luminescence studies were presented for the samples as prepared, annealed at 500°C and at 900-1000 °C. At annealing above 800°C the ceramic state was formed. It is shown that fluorapatite host is more appropriate than hydroxiapatite host for rare ions luminescence and up-conversion processes. The post preparing annealing of nanarticles significantly enhanced the luminescence intensity. The Tm/Yb doped fluorapatite shows intense up-conversion luminescence in 790-800 nm spectral region and is potentially useful for biomedical applications.

Investigations of mechanical, electronic, and magnetic properties of non-magnetic MgTe and ferro-magnetic Mg0.75 TM 0.25Te (TM = Fe, Co, Ni): An ab-initio calculation

NASA Astrophysics Data System (ADS)

Q, Mahmood; S, M. Alay-e.-Abbas; I, Mahmood; Mahmood, Asif; N, A. Noor

2016-04-01

The mechanical, electronic and magnetic properties of non-magnetic MgTe and ferro-magnetic (FM) Mg0.75 TM 0.25Te (TM = Fe, Co, Ni) in the zinc-blende phase are studied by ab-initio calculations for the first time. We use the generalized gradient approximation functional for computing the structural stability, and mechanical properties, while the modified Becke and Johnson local (spin) density approximation (mBJLDA) is utilized for determining the electronic and magnetic properties. By comparing the energies of non-magnetic and FM calculations, we find that the compounds are stable in the FM phase, which is confirmed by their structural stabilities in terms of enthalpy of formation. Detailed descriptions of elastic properties of Mg0.75 TM 0.25Te alloys in the FM phase are also presented. For electronic properties, the spin-polarized electronic band structures and density of states are computed, showing that these compounds are direct bandgap materials with strong hybridizations of TM 3d states and Te p states. Further, the ferromagnetism is discussed in terms of the Zener free electron model, RKKY model and double exchange model. The charge density contours in the (110) plane are calculated to study bonding properties. The spin exchange splitting and crystal field splitting energies are also calculated. The distribution of electron spin density is employed in computing the magnetic moments appearing at the magnetic sites (Fe, Co, Ni), as well as at the non-magnetic sites (Mg, Te). It is found that the p-d hybridization causes not only magnetic moments on the magnetic sites but also induces negligibly small magnetic moments at the non-magnetic sites.

Tm3+/Yb3+ co-doped tellurite glass with silver nanoparticles for 1.85 μm band laser material

NASA Astrophysics Data System (ADS)

Huang, Bo; Zhou, Yaxun; Cheng, Pan; Zhou, Zizhong; Li, Jun; Jin, Wei

2016-10-01

Tm3+/Yb3+ co-doped tellurite glasses with different silver nanoparticles (Ag NPs) concentrations were prepared using the conventional melt-quenching technique and characterized by the UV/Vis/NIR absorption spectra, 1.85 μm band fluorescence emission spectra, transmission electron microscopy (TEM) images, differential scanning calorimeter (DSC) curves and X-ray diffraction (XRD) patterns to investigate the effects of Ag NPs on the 1.85 μm band spectroscopic properties of Tm3+ ions, thermal stability and structural nature of glass hosts. Under the excitation of 980 nm laser diode (LD), the 1.85 μm band fluorescence emission of Tm3+ ions enhances significantly in the presence of Ag NPs with average diameter of ∼8 nm and local surface Plasmon resonance (LSPR) band of ∼590 nm, which is mainly attributed to the increased local electric field induced by Ag NPs at the proximity of doped rare-earth ions on the basis of energy transfer from Yb3+ to Tm3+ ions. An improvement by about 110% of fluorescence intensity is observed in the Tm3+/Yb3+ co-doped tellurite glass containing 0.5 mol% amount of AgNO3 while the prepared glass samples possess good thermal stability and amorphous structural nature. Meanwhile, the Judd-Ofelt intensity parameters Ωt (t = 2,4,6), spontaneous radiative transition probabilities, fluorescence branching ratios and radiative lifetimes of relevant excited levels of Tm3+ ions were determined based on the Judd-Ofelt theory to reveal the enhanced effects of Ag NPs on the 1.85 μm band spectroscopic properties, and the energy transfer micro-parameters and phonon contribution ratios were calculated based on the non-resonant energy transfer theory to elucidate the energy transfer mechanism between Yb3+ and Tm3+ ions. The present results indicate that the prepared Tm3+/Yb3+ co-doped tellurite glass with an appropriate amount of Ag NPs is a promising lasing media applied for 1.85 μm band solid-state lasers and amplifiers.

High-power diode-side-pumped rod Tm:YAG laser at 2.07 μm.

PubMed

Wang, Caili; Niu, Yanxiong; Du, Shifeng; Zhang, Chao; Wang, Zhichao; Li, Fangqin; Xu, Jialin; Bo, Yong; Peng, Qinjun; Cui, Dafu; Zhang, Jingyuan; Xu, Zuyan

2013-11-01

We report a high-power diode-laser (LD) side-pumped rod Tm:YAG laser of around 2 μm. The laser was water-cooled at 8°C and yielded a maximum output power of 267 W at 2.07 μm, which is the highest output power for an all solid-state cw 2.07 μm rod Tm:YAG laser reported as far as we know. The corresponding optical-optical conversion efficiency was 20.7%, and the slope efficiency was about 29.8%, respectively.

Analysis of Eocene depositional environments - Preliminary TM and TIMS results, Wind River Basin, Wyoming

NASA Technical Reports Server (NTRS)

Stucky, Richard K.; Krishtalka, Leonard; Redline, Andrew D.; Lang, Harold R.

1987-01-01

Both Landsat TM and aircraft Thermal IR Multispectral Scanner (TIMS) data have been used to map the lithofacies of the Wind River Basin's Eocene physical and biological environments. Preliminary analyses of these data have furnished maps of a fault contact boundary and a complex network of fluvial ribbon channel sandstones. The synoptic view thereby emerging for Eocene fluvial facies clarifies the relationships of ribbon channel sandstones to fossil-bearing overbank/floodplain facies and certain peleosols. The utility of TM and TIMS data is thereby demonstrated.

NASA's Education Program

NASA Technical Reports Server (NTRS)

1993-01-01

NASA's current education programs, which will be examined under its Strategic Plan for Education are presented. It is NASA's first goal to maintain this base - revising, expanding, or eliminating programs as necessary. Through NASA's second goal, new education reform initiatives will be added which specifically address NASA mission requirements, national educational reform, and Federal Coordinating Council for Science, Engineering, and Technology (FCCSET) priorities. The chapters in this publication are divided by educational levels, with additional sections on programs to improve the technological competence of students and on an array of NASA published materials to supplement programs. The resource section lists NASA's national and regional Teacher Resource Centers and introduces the reader to NASA's Central Operation of Resources for Educators (CORE), which distributes materials in audiovisual format.

ISS NASA Social

NASA Image and Video Library

2013-02-20

Marshall Porterfield, Life and Physical Sciences Division Director at NASA Headquarters, talks about the human body in microgravity and other life sciences at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

ISS NASA Social

NASA Image and Video Library

2013-02-20

A NASA Social participant asks a question to the astronauts onboard the International Space Station in a live downlink from the ISS at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Photo Credit: (NASA/Carla Cioffi)

Landsat TM Classifications For SAFIS Using FIA Field Plots

Treesearch

William H. Cooke; Andrew J. Hartsell

2001-01-01

Wall-to-wall Landsat Thematic Mapper (TM) classification efforts in Georgia require field validation. We developed a new crown modeling procedure based on Forest Health Monitoring (FHM) data to test Forest Inventory and Analysis (FIA) data. These models simulate the proportion of tree crowns that reflect light on a FIA subplot basis. We averaged subplot crown...

Overmoded subterahertz surface wave oscillator with pure TM{sub 01} mode output

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Guangqiang; Zeng, Peng; Wang, Dongyang

2016-02-15

Overmoded O-type Cerenkov generators using annular electron beams are facing the problem of multi-modes output due to the inevitable structural discontinuities. A simple but effective method to achieve the pure TM{sub 01} mode output is applied on the 0.14 THz overmoded surface wave oscillator (SWO) in this paper. In spite of still using an overmoded slow wave structure to ensure the easy fabrication, the followed smooth circular waveguide is shrinkingly tapered to the output waveguide with appropriate radius that it cuts off other higher modes except TM{sub 01} mode. Moreover, the modified device here has the same power capacity as themore » previous one according to the numerical analysis. By optimized lengths of the transition waveguide and tapered waveguide, particle-in-cell simulation results indicate that the subterahertz wave with output power increased 14.2% at the same frequency is obtained from the proposed SWO under the previous input conditions, and importantly, the output power is all carried by TM{sub 01} mode as expected. Further simulation results in the pulse regime confirm the feasibility of the optimized structure in the actual experiments. This simple and viable design is also applicable to overmoded devices in the lower frequency band of subterahertz wave.« less

NASA strategic plan

NASA Technical Reports Server (NTRS)

1994-01-01

The NASA Strategic Plan is a living document. It provides far-reaching goals and objectives to create stability for NASA's efforts. The Plan presents NASA's top-level strategy: it articulates what NASA does and for whom; it differentiates between ends and means; it states where NASA is going and what NASA intends to do to get there. This Plan is not a budget document, nor does it present priorities for current or future programs. Rather, it establishes a framework for shaping NASA's activities and developing a balanced set of priorities across the Agency. Such priorities will then be reflected in the NASA budget. The document includes vision, mission, and goals; external environment; conceptual framework; strategic enterprises (Mission to Planet Earth, aeronautics, human exploration and development of space, scientific research, space technology, and synergy); strategic functions (transportation to space, space communications, human resources, and physical resources); values and operating principles; implementing strategy; and senior management team concurrence.

MOP03TM (HDF)

Atmospheric Science Data Center

... from Thermal Infrared Radiances, version 6, Hampton, VA, USA:NASA Atmospheric Science Data Center (ASDC), Accessed   at doi: 10.5067/TERRA/MOPITT/DATA305. Project Title:  MOPITT ...

2016-10-05

... from Thermal Infrared Radiances, version 6, Hampton, VA, USA:NASA Atmospheric Science Data Center (ASDC), Accessed   at doi: 10.5067/TERRA/MOPITT/DATA305. Project Title:  MOPITT ...

Modular to Monoblock: Difficulties of Detaching the M(2)a-Magnum(TM) Head Are Common in Metal-on-metal Revisions.

PubMed

Mäntymäki, Heikki; Mäkelä, Keijo T; Vahlberg, Tero; Hirviniemi, Joni; Niinimäki, Tuukka

2016-09-01

Modern hip implants typically feature modular heads, which allow for easy exchange and removal from the femoral stem at the time of revision. However, owing to fretting, corrosion, or cold welding, the modular head may be difficult or impossible to separate from the underlying trunnion, especially if the implant has titanium interfaces between the head and the stem. We have repeatedly encountered difficulty removing the titanium sleeve adapter in the M(2)a-Magnum(TM) implant. Although the manufacturer warns about this complication and cases with these difficulties have been reported to the United States FDA, we believed this topic is important to study, because the frequency of difficulties in head removal is unknown and the complications related to this event have not been characterized. We asked: (1) Do revisions of M(2)a-Magnum(TM) implants differ from those of M(2)a-38(TM) implants in terms of ease of removal of the femoral head? (2) In cases where difficulty with M(2)a-Magnum(TM) head removal occurred, was the operative time, bleeding, risk of periprosthetic fracture, or joint infection increased compared with cases where the M(2)a-Magnum(TM) head was removed without difficulties? Between 2004 and 2014, we revised 296 THAs with metal-on-metal implants that involved M(2)a-Magnum(TM) (123) or M(2)a-38(TM) heads (88); of those, 84 were planned to include a femoral stem revision and insufficient data were available for three operations, so they were excluded from this analysis, leaving 124 THAs in the current retrospective study (70 THAs with M(2)a-Magnum(TM) and 54 THAs with M(2)a-38(TM) heads).The method of modular head removal, any difficulties removing the femoral head from the trunnion, operation time, and complications were recorded based on chart review. All the observed problems of detaching the head or taper adapter were among M(2)a-Magnum(TM) heads; there were no problems detaching the head in revisions of the M(2)a-38(TM) implant. In 29% (20 of 70) of

Double NIR laser stimulation and enhancing the thermal sensitivity of Er3+/Tm3+/Nd3+ doped multilayer core-shell nanoparticles.

PubMed

Ba, Zhaojing; Hu, Min; Zhao, Yiming; Wang, Yiqing; Wang, Jing; Zhang, Zhenxi

2018-08-31

Non-contact thermal sensors are important devices to study cellular processes and monitor temperature in vivo. Herein, a novel highly sensitive nanothermometer based on NaYF 4 :Yb,Er@ NaYF 4 @NaYF 4 :Yb,Tm@ NaYF 4 :Nd (denoted as Er@Y@Tm@Nd) was prepared by a facile solvothermal method. When excited by the near-infrared (NIR) light of 808 and 980 nm, the as-prepared Er@Y@Tm@Nd nanoparticles could emit both blue and green light, respectively, since the lanthanide cations responsible for these emissions are gathered inside this nanostructure. The green and blue light intensity ratio exhibits obvious temperature dependence in the range of the physiological temperature. Additionally, the fluorescence intensity of Er 3+ and Tm 3+ are also greatly enhanced due to the multilayer structure that implies avoiding the Er 3+ and Tm 3+ energy cross-relaxation by introduction of a NaYF 4 wall between them. The as-prepared core-shell-shell-shell structure with Er 3+ and Tm 3+ in different layers improves dozens of times of the thermal sensitivity based on the non-thermal coupling levels of the probe: the maximum values for the sensitivity are 2.95% K -1 (I Er-521 /I Tm-450 ) and 6.30% K -1 (I Tm-474 /I Er-541 ) when excited by 980 and 808 nm laser sources, respectively. These values are well above those previously reported (<0.7% K -1 ), indicating that the prepared nanostructures are temperature sensors with excellent thermal sensitivity and sensitive to NIR wavelength excitation that makes them highly preferred for thermal detection.

LADEE NASA Social

NASA Image and Video Library

2013-09-05

NASA Associate Administrator for the Science Mission Directorate John Grunsfeld talks during a NASA Social about the Lunar Atmosphere and Dust Environment Explorer (LADEE) mission at the NASA Wallops Flight Facility, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

LADEE NASA Social

NASA Image and Video Library

2013-09-05

NASA Lunar Atmosphere and Dust Environment Explorer (LADEE) Program Scientist Sarah Noble talks during a NASA Social about the LADEE mission at NASA Wallops Flight Facility, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

LADEE NASA Social

NASA Image and Video Library

2013-09-05

Bob Barber, Lunar Atmosphere and Dust Environment Explorer (LADEE) Spacecraft Systems Engineer at NASA Ames Research Center, points to a model of the LADEE spacecraft a NASA Social, Thursday, Sept. 5, 2013 at NASA Wallops Flight Facility in Virginia. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

A comparison of LANDSAT TM to MSS imagery for detecting submerged aquatic vegetation in lower Chesapeake Bay

NASA Technical Reports Server (NTRS)

Ackleson, S. G.; Klemas, V.

1985-01-01

LANDSAT Thematic Mapper (TM) and Multispectral Scanner (MSS) imagery generated simultaneously over Guinea Marsh, Virginia, are assessed in the ability to detect submerged aquatic, bottom-adhering plant canopies (SAV). An unsupervised clustering algorithm is applied to both image types and the resulting classifications compared to SAV distributions derived from color aerial photography. Class confidence and accuracy are first computed for all water areas and then only shallow areas where water depth is less than 6 feet. In both the TM and MSS imagery, masking water areas deeper than 6 ft. resulted in greater classification accuracy at confidence levels greater than 50%. Both systems perform poorly in detecting SAV with crown cover densities less than 70%. On the basis of the spectral resolution, radiometric sensitivity, and location of visible bands, TM imagery does not offer a significant advantage over MSS data for detecting SAV in Lower Chesapeake Bay. However, because the TM imagery represents a higher spatial resolution, smaller SAV canopies may be detected than is possible with MSS data.

Tm:KLu(WO(4))(2) microchip laser Q-switched by a graphene-based saturable absorber.

PubMed

Serres, Josep Maria; Loiko, Pavel; Mateos, Xavier; Yumashev, Konstantin; Griebner, Uwe; Petrov, Valentin; Aguiló, Magdalena; Díaz, Francesc

2015-06-01

We report on the first Tm-doped double tungstate microchip laser Q-switched with graphene using a Tm:KLu(WO₄)₂ crystal cut along the N_g dielectric axis. This laser generates a maximum average output power of 310 mW with a slope efficiency of 13%. At a repetition rate of 190 kHz the shortest pulses with 285 ns duration and 1.6 µJ energy are achieved.

Relativistic backward wave oscillator operating in TM02 with cutoff-type resonant reflector

NASA Astrophysics Data System (ADS)

Teng, Yan; Shi, Yanchao; Yang, Dewen; Cao, Yibing; Zhang, Zhijun

2017-04-01

This paper proposes an overmoded relativistic backward wave oscillator (RBWO) operating in the TM02 mode with the cutoff-type resonant reflector characterized by the advantages of the cutoff neck and the single resonant cavity. In order to protect the explosive emission of the annular cathode from the disturbance of the microwave leakage, the cutoff-type resonant reflector can effectively prevent the microwave consisting of several modes from propagating into the diode region. Attributed to the strong reflections caused by the cutoff-type resonant reflector at the front end of the overmoded slow-wave structure (SWS), the overmoded RBWO works in the state of the strong resonance, which enhances the beam-to-microwave power conversion efficiency. TM02 is selected as the operation mode so as to increase the power handling capability. The nonuniform SWS depresses the cross-excitation of the unwanted longitudinal modes of TM02 and improves the synchronous interaction between the electron beam and the structure wave. It is found that when we make the peak values of the longitudinal electric field and the modulated current appear nearly at the same position in the overmoded SWS by optimizing the electrodynamic structure, the conversion efficiency will be enhanced significantly. In the numerical simulation, the microwave generation with power 2.99 GW and efficiency 0.45 is obtained under the diode voltage 851 kV and current 7.8 kA with the guide magnetic field of 4.3 T. The microwave generation with the pure frequency spectrum of 10.083 GHz radiates in the TM01 mode. The conversion efficiency keeps above 0.40 over the diode voltage range of 220 kV.

Energy transfer processes between Tm(3+) and Ho(3+) in LiYF4. Ph.D. Thesis Final Report

NASA Technical Reports Server (NTRS)

Oezen, Goenuel

1991-01-01

The spectroscopic properties of the crystal LiYF4 doped with Thulium (Tm) and Holmium (Ho) ions are studied. The basic processes are discussed that regulate the transfer of energy between these two ions in this crystal. In this system Tm is considered the donor ion and the Ho the acceptor ion. Spectral data were obtained on three samples available: LiYF4:Tm(3+) (0.5 percent), LiYF4:Ho(3+) (1 percent), and LiYF4:Tm(3+) (5 percent), Ho(3+) (0.2 percent). Spectral data, which include absorption, luminescence, excitation, and the response to pulsed excitation in a wide range of temperatures, allowed to look at the energy transfer processes by considering the kinetic evolution of the emission of the two ions (donor and acceptor) involved in the process and the basic spectroscopic properties related to them. This inclusive approach has led to the validation of the physical model.

Comparison between refraction measured by Spot Vision ScreeningTM and subjective clinical refractometry

PubMed Central

de Jesus, Daniela Lima; Villela, Flávio Fernandes; Orlandin, Luis Fernando; Eiji, Fernando Naves; Dantas, Daniel Oliveira; Alves, Milton Ruiz

2016-01-01

OBJECTIVE: The purpose of this study was to evaluate the accuracy of Spot Vision ScreeningTM as an autorefractor by comparing refraction measurements to subjective clinical refractometry results in children and adult patients. METHODS: One-hundred and thirty-four eyes of 134 patients were submitted to refractometry by Spot and clinical refractometry under cycloplegia. Patients, students, physicians, staff and children of staff from the Hospital das Clínicas (School of Medicine, University of São Paulo) aged 7-50 years without signs of ocular disease were examined. Only right-eye refraction data were analyzed. The findings were converted in magnitude vectors for analysis. RESULTS: The difference between Spot Vision ScreeningTM and subjective clinical refractometry expressed in spherical equivalents was +0.66±0.56 diopters (D), +0.16±0.27 D for the vector projected on the 90 axis and +0.02±0.15 D for the oblique vector. CONCLUSIONS: Despite the statistical significance of the difference between the two methods, we consider the difference non-relevant in a clinical setting, supporting the use of Spot Vision ScreeningTM as an ancillary method for estimating refraction. PMID:26934234

Spectral Properties of Er3+/Tm3+ Co-Doped ZBLAN Glasses and Fibers

PubMed Central

Liao, Xili; Jiang, Xiaobo; Yang, Qiuhong; Wang, Longfei; Chen, Danping

2017-01-01

A series of Er3+/Tm3+ co-doped fluoride (ZBLAN) glasses and fibers was prepared and their fluorescence spectra was measured under excitation at 793 nm and 980 nm. Correlation between the self-absorption effect of rare-earth ions and the shift of the emission peak was investigated. With the increasing length of fiber, the emission peaks red-shift when self-absorption occurs at the upper level of emission transition or blue-shift when that occurs at the lower level. As a result of the strong self-absorption effect, Er3+/Tm3+ co-doped fibers mainly yield 1390–1470, 1850–1980, and 2625–2750 nm emissions when excited at 793 nm, and 1480–1580, 1800–1980, and 2625–2750 nm emissions when excited at 980 nm. Further, a broadband emission in the range of 1410–1580 nm covering the S + C communication band was obtained by the dual-pumping scheme of 793 nm and 980 nm. Results suggest that the dual-pumping scheme would be more effective and important for an Er3+/Tm3+ co-doped fiber amplifier working in the S + C communication band. PMID:28772846

Spectral Properties of Er3+/Tm3+ Co-Doped ZBLAN Glasses and Fibers.

PubMed

Liao, Xili; Jiang, Xiaobo; Yang, Qiuhong; Wang, Longfei; Chen, Danping

2017-05-03

A series of Er 3+ /Tm 3+ co-doped fluoride (ZBLAN) glasses and fibers was prepared and their fluorescence spectra was measured under excitation at 793 nm and 980 nm. Correlation between the self-absorption effect of rare-earth ions and the shift of the emission peak was investigated. With the increasing length of fiber, the emission peaks red-shift when self-absorption occurs at the upper level of emission transition or blue-shift when that occurs at the lower level. As a result of the strong self-absorption effect, Er 3+ /Tm 3+ co-doped fibers mainly yield 1390-1470, 1850-1980, and 2625-2750 nm emissions when excited at 793 nm, and 1480-1580, 1800-1980, and 2625-2750 nm emissions when excited at 980 nm. Further, a broadband emission in the range of 1410-1580 nm covering the S + C communication band was obtained by the dual-pumping scheme of 793 nm and 980 nm. Results suggest that the dual-pumping scheme would be more effective and important for an Er 3+ /Tm 3+ co-doped fiber amplifier working in the S + C communication band.

NASA Alumni League Dialogue

NASA Image and Video Library

2011-03-04

Former NASA Administrator James Beggs, left, and present NASA Administrator Charles Bolden conduct a dialogue on the future of the space program, Friday, March 4, 2011, at NASA Headquarters in Washington. Beggs was NASA's sixth administrator serving from July 1981 to December 1985. Bolden took over the post as NASA's 12th administrator in July 2009. The dialogue is part of the program “The State of the Agency: NASA Future Programs Presentation” sponsored by the NASA Alumni League with support from the AAS, AIAA, CSE and WIA.Photo Credit: (NASA/Paul E. Alers)

White light upconversion emission in Yb3+/ Er3+/ Tm3+ codoped oxy-fluoride lithium tungsten tellurite glass ceramics

NASA Astrophysics Data System (ADS)

Ansari, Ghizal F.; Mahajan, S. K.

2012-02-01

The bright white upconversion emission ( tri-colour UC) is generated in Er/Tm/Yb tri -doped oxy-fluoride lithium tungsten tellurite (TWLOF)glass ceramics containing crystalline phase LiYbF4 under the excitation of 980nm laser diode. The most appropriate combination of rare-earth ions (2mol% YbF3 1mol% ErF3 and 1mol%TmF3 )of glass ceramic sample has been determined to tune the primary colour (RGB and generate white light emission. By varying the pump power, intense and weak blue (487nm, 437nm), green (525nm and 545nm) and red (662nm) emission are simultaneously observed at room temperature. The dependence of upconversion emission intensity suggest that a theephoton process is responsible for the blue emission of Tm3+ ions and red emission due to both Tm3+ and Er3+ ions , while green emission originated from two photon processes in Er3+ ions. Also tri colour upconvesion and energy transfer in this glass ceramics sample were studied under 808nm laser diode excitation. The Upconversion mechanisms and Tm3+ ions plays role of both emitter and activator (transfer energy to Er) were discussed.

14 CFR 1240.105 - Special initial awards-NASA and NASA contractor employees.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 14 Aeronautics and Space 5 2013-01-01 2013-01-01 false Special initial awards-NASA and NASA... initial awards—NASA and NASA contractor employees. (a) Patent Application Awards. (1) When the Board... Property or the Patent or Intellectual Property Counsel at a NASA Center that an invention made by an...

Acting Administrator Robert Lightfoot Discusses NASAs FY2018 NASA Budget Request

NASA Image and Video Library

2017-05-23

Acting NASA Administrator Robert Lightfoot discussed the agency’s Fiscal Year 2018 budget request on May 23, during an agencywide town hall State of NASA address at NASA Headquarters in Washington. The address also was broadcast on NASA Television and streamed on the agency’s homepage and mobile apps.

A technique for extrapolating and validating forest cover across large regions. Calibrating AVHRR data with TM data

Treesearch

L.R. Iverson; E.A. Cook; R.L. Graham

1989-01-01

An approach to extending high-resolution forest cover information across large regions is presented and validated. Landsat Thematic Mapper (TM) data were classified into forest and nonforest for a portion of Jackson County, Illinois. The classified TM image was then used to determine the relationship between forest cover and the spectral signature of Advanced Very High...

[A study on the concentration quenching of Tm3+ upconversion luminescence].

PubMed

Chen, B; Wang, H; Huang, S

2001-06-01

In this work, we have a designation and preparation of MFT glasses for upconversion, the glasses consisted of TeO2 and fluoride: PbF2, AlF3, BaF2, NaF and the impurity Tm2O3. In this glass system the oxide improve forming ability, the fluorides improve the microscopic environment around RE ions in glasses. In this glass host the content of Tm2O3 achieves to 4% mol and crystallization no occurred. A detail study on the concentration quenching of upconversion luminescence for 1G4-->3H6 and 1D2-->3H4 transitions was completed. The experimental results directed that the quenching concentration was 0.6 mol.% and higher 3 times than in other glasses materials. The cross relaxation and mechanism of concentration quenching were discussed.

Research in NASA history: A guide to the NASA history program

NASA Technical Reports Server (NTRS)

1992-01-01

This report describes the research opportunities and accomplishments of NASA's agency wide history program. It also offers a concise guide to the historical documentary resources available at NASA Headquarters in Washington D.C., at NASA facilities located around the country, and through the federal records system. In addition, this report contains expanded contributions by Lee D. Saegessor and other members of the NASA Headquarters History Division and by those responsible for historical documents and records at some NASA centers.

Cross talk between the TM4SF5/focal adhesion kinase and the interleukin-6/STAT3 pathways promotes immune escape of human liver cancer cells.

PubMed

Ryu, Jihye; Kang, Minkyung; Lee, Mi-Sook; Kim, Hye-Jin; Nam, Seo Hee; Song, Haeng Eun; Lee, Doohyung; Lee, Jung Weon

2014-08-01

TM4SF5 overexpressed in hepatocellular carcinoma activates focal adhesion kinase (FAK) during tumor cell migration. However, it remains unknown how TM4SF5 in hepatocellular carcinoma cells compromises with immune actions initiated by extracellular cytokines. Normal and cancerous hepatocytes with or without TM4SF5 expression were analyzed for the effects of cytokine signaling activity on TM4SF5/FAK signaling and metastatic potential. We found that interleukin-6 (IL-6) was differentially expressed in hepatocytes depending on cancerous malignancy and TM4SF5 expression. IL-6 treatment activated FAK and STAT3 and enhanced focal adhesion (FA) formation in TM4SF5-null cells, but it decreased TM4SF5-dependent FAK activity and FA formation in SNU761-TM4SF5 cells. STAT3 suppression abolished the IL-6-mediated effects in normal Chang cells, but it did not recover the TM4SF5-dependent FAK activity that was inhibited by IL-6 treatment in cancerous SNU761-TM4SF5 cells. In addition, modulation of FAK activity did not change the IL-6-mediated STAT3 activity in either the Chang or SNU761 cell system. TM4SF5 expression in SNU761 cells caused invasive extracellular matrix degradation negatively depending on IL-6/IL-6 receptor (IL-6R) signaling. Thus, it is likely that hepatic cancer cells adopt TM4SF5-dependent FAK activation and metastatic potential by lowering IL-6 expression and avoiding its immunological action through the IL-6-STAT3 pathway. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

Information theoretic comparisons of original and transformed data from Landsat MSS and TM

NASA Technical Reports Server (NTRS)

Malila, W. A.

1985-01-01

The dispersion and concentration of signal values in transformed data from the Landsat-4 MSS and TM instruments are analyzed using a communications theory approach. The definition of entropy of Shannon was used to quantify information, and the concept of mutual information was employed to develop a measure of information contained in several subsets of variables. Several comparisons of information content are made on the basis of the information content measure, including: system design capacities; data volume occupied by agricultural data; and the information content of original bands and Tasseled Cap variables. A method for analyzing noise effects in MSS and TM data is proposed.

Dixie Valley, Nevada playa bathymetry constructed from Landsat TM data

NASA Astrophysics Data System (ADS)

Groeneveld, David P.; Barz, David D.

2014-05-01

A bathymetry model was developed from a series of Landsat Thematic Mapper (TM) images to assist discrimination of hydrologic processes on a low-relief, stable saline playa in Dixie Valley, Nevada, USA. The slope of the playa surface, established by field survey on a reference transect, enabled calculation of relative elevation of the edges of pooled brine mapped from Landsat TM5 band 5 reflectance (TMB5) in the 1.55-1.75 μm shortwave infrared region (SWIR) of the spectrum. A 0.02 TMB5 reflectance threshold accurately differentiated the shallow (1-2 mm depth) edges of pools. Isocontours of equal elevations of pool margins were mapped with the TMB5 threshold, forming concentric rings that were assigned relative elevations according to the position that the pool edges intersected the reference transect. These data were used to fit a digital elevation model and a curve for estimating pooled volume given the distance from the playa edge to the intersection of the pool edge with the reference transect. To project pooled volume using the bathymetric model for any TM snapshot, within a geographic information system, the 0.02 TMB5 threshold is first used to define the edge of the exposed brine. The distance of this edge from the playa edge along the reference transect is then measured and input to the bathymetric equation to yield pooled volume. Other satellite platforms with appropriate SWIR bands require calibration to Landsat TMB5. The method has applicability for filling reservoirs, bodies of water that fluctuate and especially bodies of water inaccessible to acoustic or sounding methods.

LADEE NASA Social

NASA Image and Video Library

2013-09-05

NASA Associate Administrator for the Science Mission Directorate John Grunsfeld is seen in a video monitor during a NASA Social about the Lunar Atmosphere and Dust Environment Explorer (LADEE) mission at the NASA Wallops Flight Facility, Thursday, Sept. 5, 2013 on Wallops Island, VA. Fifty of NASA's social media followers are attending a two-day event in support of the LADEE launch. Data from LADEE will provide unprecedented information about the environment around the moon and give scientists a better understanding of other planetary bodies in our solar system and beyond. LADEE is scheduled to launch at 11:27 p.m. Friday, Sept. 6, from NASA's Wallops Flight Facility. Photo Credit: (NASA/Carla Cioffi)

75 FR 70951 - NASA Advisory Council; NASA Commercial Space Committee; Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-19

... NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [Notice: (10-148)] NASA Advisory Council; NASA... Committee of the NASA Advisory Council. DATES: Tuesday, December 14, 2010, 1:30 p.m.-4:30 p.m., Local Time. ADDRESSES: NASA Headquarters, 300 E Street, SW., Glennan Conference Center Room 1Q39, Washington, DC 20546...

Bacteria of the Candidate Phylum TM7 are Prevalent in Acidophilic Nitrifying Sequencing-Batch Reactors

PubMed Central

Hanada, Akiko; Kurogi, Takashi; Giang, Nguyen Minh; Yamada, Takeshi; Kamimoto, Yuki; Kiso, Yoshiaki; Hiraishi, Akira

2014-01-01

Laboratory-scale acidophilic nitrifying sequencing-batch reactors (ANSBRs) were constructed by seeding with sewage-activated sludge and cultivating with ammonium-containing acidic mineral medium (pH 4.0) with or without a trace amount of yeast extract. In every batch cycle, the pH varied between 2.7 and 4.0, and ammonium was completely converted to nitrate. Attempts to detect nitrifying functional genes in the fully acclimated ANSBRs by PCR with previously designed primers mostly gave negative results. 16S rRNA gene-targeted PCR and a subsequent denaturating gradient gel electrophoresis analysis revealed that a marked change occurred in the bacterial community during the overall period of operation, in which members of the candidate phylum TM7 and the class Gammaproteobacteria became predominant at the fully acclimated stage. This result was fully supported by a 16S rRNA gene clone library analysis, as the major phylogenetic groups of clones detected (>5% of the total) were TM7 (33%), Gammaproteobacteria (37%), Actinobacteria (10%), and Alphaproteobacteria (8%). Fluorescence in situ hybridization with specific probes also demonstrated the prevalence of TM7 bacteria and Gammaproteobacteria. These results suggest that previously unknown nitrifying microorganisms may play a major role in ANSBRs; however, the ecophysiological significance of the TM7 bacteria predominating in this process remains unclear. PMID:25241805

Understanding the multiferroicity in TmMn2O5 by a magnetically induced ferrielectric model

PubMed Central

Yang, L.; Li, X.; Liu, M. F.; Li, P. L.; Yan, Z. B.; Zeng, M.; Qin, M. H.; Gao, X. S.; Liu, J.-M.

2016-01-01

The magnetically induced electric polarization behaviors in multiferroic TmMn2O5 in response to varying temperature and magnetic field are carefully investigated by means of a series of characterizations including the high precision pyroelectric current technique. Here polycrystalline rather than single crystal samples are used for avoiding the strong electrically self-polarized effect in single crystals, and various parallel experiments on excluding the thermally excited current contributions are performed. The temperature-dependent electric polarization flop as a major character is identified for different measuring paths. The magneto-current measurements indicate that the electric polarization in the low temperature magnetic phase region has different origin from that in the high temperature magnetic phase. It is suggested that the electric polarization does have multiple components which align along different orientations, including the Mn3+-Mn4+-Mn3+ exchange striction induced polarization PMM, the Tm3+-Mn4+-Tm3+ exchange striction induced polarization PTM, and the low temperature polarization PLT probably associated with the Tm3+ commensurate phase. The observed electric polarization flop can be reasonably explained by the ferrielectric model proposed earlier for DyMn2O5, where PMM and PTM are the two antiparallel components both along the b-axis and PLT may align along the a-axis. Finally, several issues on the unusual temperature dependence of ferroelectric polarizations are discussed. PMID:27713482

ISS NASA Social

NASA Image and Video Library

2013-02-20

Expedition 33/34 astronauts onboard the International Space Station answer questions in a live downlink at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. Seen from left to right are NASA astronauts Tom Marshburn, Kevin Ford and Canadian Space Agency (CSA) astronaut Chris Hadfield. Photo Credit: (NASA/Carla Cioffi)

Positive influence of Tm3+ on effective Er3+: 3 μm emission in fluoride glass under 980 nm excitation

NASA Astrophysics Data System (ADS)

Huang, Feifei; Wang, Tao; Guo, Yanyan; Lei, Ruoshan; Xu, Shiqing

2017-05-01

Er3+ and Tm3+ singly doped and codoped new fluoride glasses were prepared by traditional melt-quenching method. Efficient 3 μm emission was obtained under 980 nm laser excitation. It is worthy to notice that one of the two ions can be the sensitizer to the other one by depressing the Er3+: 1.5 μm emission through the energy transfer process from Er3+:4I13/2 level to Tm3+:3F4 level. On the basis of measured absorption spectra, the Judd-Ofelt intensity parameters and radiation emission probability were calculated to evaluate the spectroscopic properties. Additionally, the micro-parameters together with the phonon assistance of Er3+:4I13/2 → Tm3+:3F4 and Er3+:4I11/2 → Tm3+:3H5 processes were quantitatively analyzed by using Dexter model. The theoretical micro-parameters results meet well with the experiments which indicates that Er3+/Tm3+ codoped fluoride glass is a potential kind laser glass for 3 μm laser.

Internal NASA Study: NASAs Protoflight Research Initiative

NASA Technical Reports Server (NTRS)

Coan, Mary R.; Hirshorn, Steven R.; Moreland, Robert

2015-01-01

The NASA Protoflight Research Initiative is an internal NASA study conducted within the Office of the Chief Engineer to better understand the use of Protoflight within NASA. Extensive literature reviews and interviews with key NASA members with experience in both robotic and human spaceflight missions has resulted in three main conclusions and two observations. The first conclusion is that NASA's Protoflight method is not considered to be "prescriptive." The current policies and guidance allows each Program/Project to tailor the Protoflight approach to better meet their needs, goals and objectives. Second, Risk Management plays a key role in implementation of the Protoflight approach. Any deviations from full qualification will be based on the level of acceptable risk with guidance found in NPR 8705.4. Finally, over the past decade (2004 - 2014) only 6% of NASA's Protoflight missions and 6% of NASA's Full qualification missions experienced a publicly disclosed mission failure. In other words, the data indicates that the Protoflight approach, in and of it itself, does not increase the mission risk of in-flight failure. The first observation is that it would be beneficial to document the decision making process on the implementation and use of Protoflight. The second observation is that If a Project/Program chooses to use the Protoflight approach with relevant heritage, it is extremely important that the Program/Project Manager ensures that the current project's requirements falls within the heritage design, component, instrument and/or subsystem's requirements for both the planned and operational use, and that the documentation of the relevant heritage is comprehensive, sufficient and the decision well documented. To further benefit/inform this study, a recommendation to perform a deep dive into 30 missions with accessible data on their testing/verification methodology and decision process to research the differences between Protoflight and Full Qualification

The NASA Severe Thunderstorm Observations and Regional Modeling (NASA STORM) Project

NASA Technical Reports Server (NTRS)

Schultz, Christopher J.; Gatlin, Patrick N.; Lang, Timothy J.; Srikishen, Jayanthi; Case, Jonathan L.; Molthan, Andrew L.; Zavodsky, Bradley T.; Bailey, Jeffrey; Blakeslee, Richard J.; Jedlovec, Gary J.

2016-01-01

The NASA Severe Storm Thunderstorm Observations and Regional Modeling(NASA STORM) project enhanced NASA’s severe weather research capabilities, building upon existing Earth Science expertise at NASA Marshall Space Flight Center (MSFC). During this project, MSFC extended NASA’s ground-based lightning detection capacity to include a readily deployable lightning mapping array (LMA). NASA STORM also enabled NASA’s Short-term Prediction and Research Transition (SPoRT) to add convection allowing ensemble modeling to its portfolio of regional numerical weather prediction (NWP) capabilities. As a part of NASA STORM, MSFC developed new open-source capabilities for analyzing and displaying weather radar observations integrated from both research and operational networks. These accomplishments enabled by NASA STORM are a step towards enhancing NASA’s capabilities for studying severe weather and positions them for any future NASA related severe storm field campaigns.

NASA Social

NASA Image and Video Library

2011-05-18

Gwynne Shotwell, President of SpaceX, speaks during a NASA Social, Friday, May 18, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

NASA Social

NASA Image and Video Library

2012-05-18

Models of various rockets line a table at a NASA Social, Friday, May 18, 2012, at Kennedy Space Center in Cape Canaveral, Fla. About 50 NASA Social followers attended an event as part of activities surrounding the launch of Space Exploration Technologies, or SpaceX, demonstration mission of the company's Falcon 9 rocket to the International Space Station. Photo Credit: (NASA/Paul E. Alers)

Landsat TM image maps of the Shirase and Siple Coast ice streams, West Antarctica

USGS Publications Warehouse

Ferrigno, Jane G.; Mullins, Jerry L.; Stapleton, Jo Anne; Bindschadler, Robert; Scambos, Ted A.; Bellisime, Lynda B.; Bowell, Jo-Ann; Acosta, Alex V.

1994-01-01

Fifteen 1: 250000 and one 1: 1000 000 scale Landsat Thematic Mapper (TM) image mosaic maps are currently being produced of the West Antarctic ice streams on the Shirase and Siple Coasts. Landsat TM images were acquired between 1984 and 1990 in an area bounded approximately by 78°-82.5°S and 120°- 160° W. Landsat TM bands 2, 3 and 4 were combined to produce a single band, thereby maximizing data content and improving the signal-to-noise ratio. The summed single band was processed with a combination of high- and low-pass filters to remove longitudinal striping and normalize solar elevation-angle effects. The images were mosaicked and transformed to a Lambert conformal conic projection using a cubic-convolution algorithm. The projection transformation was controled with ten weighted geodetic ground-control points and internal image-to-image pass points with annotation of major glaciological features. The image maps are being published in two formats: conventional printed map sheets and on a CD-ROM.

PNPLA3 rs738409 and TM6SF2 rs58542926 variants increase the risk of hepatocellular carcinoma in alcoholic cirrhosis.

PubMed

Falleti, Edmondo; Cussigh, Annarosa; Cmet, Sara; Fabris, Carlo; Toniutto, Pierluigi

2016-01-01

PNPLA3 rs738409 polymorphism is associated with fatty liver disease, alcoholic or non-alcoholic (NAFLD) and hepatocellular carcinoma (HCC). TM6SF2 rs58542926 is clearly associated with NAFLD, but it is not clearly associated with HCC. The relationship between TM6SF2 rs58542926 and HCC and the potential synergistic effect of TM6SF2 and PNPLA3 variants in modifying the risk of HCC are not known. This study assessed the interaction between PNPLA3 rs738409 and TM6SF2 rs58542926 variants in the conditioning of HCC development. A total of 511 cirrhotic patients (44% alcohol-related, 56% viral, 57.5% liver transplanted) were retrospectively investigated for HCC occurrence. PNPLA3 rs734809 and TM6SF2 rs58542926 were genotyped using restriction fragment length polymorphism and real-time allelic discrimination polymerase chain reaction methods. Patients with HCC were more likely to be PNPLA3 rs734809 G/G homozygotes (41/150 vs. 60/361, p=0.009) or TM6SF2 rs58542926 C/T-T/T (27/150 vs. 41/361, p=0.044). The presence of either PNPLA3 G/G or TM6SF2*/T identified high-risk genotypes for HCC, which were strongly associated with HCC (64/150 vs. 93/361, p=0.0002). This association was evident in alcohol-related (p=0.0007) but not in viral cirrhosis. TM6SF2 C/T or T/T in conjunction with PNPLA3 G/G variants may be potential genetic risk factors for developing HCC in alcohol-related cirrhosis. Copyright © 2015 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

Too Good for Drugs[TM]. What Works Clearinghouse Intervention Report

ERIC Educational Resources Information Center

What Works Clearinghouse, 2006

2006-01-01

"Too Good for Drugs"[TM] is designed to promote life skills, character values, resistance skills to negative peer influence, and resistance to the use of illegal drugs, alcohol, and tobacco. The program, which targets elementary and middle school students, is based on classroom discussions and structured activities that center on…

NASA Alumni League Dialogue

NASA Image and Video Library

2011-03-04

Former NASA Administrator James Beggs is seen during a dialogue with present NASA Administrator Charles Bolden on the future of the space program, Friday, March 4, 2011, at NASA Headquarters in Washington. Beggs was NASA's sixth administrator serving from July 1981 to December 1985. The dialogue was part of the program “The State of the Agency: NASA Future Programs Presentation” sponsored by the NASA Alumni League with support from the AAS, AIAA, CSE and WIA.Photo Credit: (NASA/Paul E. Alers)

ISS NASA Social

NASA Image and Video Library

2013-02-20

Marshall Porterfield, Life and Physical Sciences Division Director at NASA Headquarters, talks about the human body in microgravity and other life sciences at a NASA Social exploring science on the ISS at NASA Headquarters, Wednesday, Feb. 20, 2013 in Washington. In the foreground is pictured Veggie, a container used for growing plants on the ISS. Photo Credit: (NASA/Carla Cioffi)

Fact Sheets of CTAS and NASA Decision-Support Tools and Concepts

NASA Technical Reports Server (NTRS)

Lee, Katharine

2004-01-01

Distributed Air/Ground (DAG) Traffic Management (TM) is an integrated operational concept in which flight deck crews, air traffic service providers and aeronautical operational control personnel use distributed decision-making to enable user preferences and increase system capacity, while meeting air traffic management (ATM) requirements. It is a possible operational mode under the Free Flight concept outlined by the RTCA Task Force 3. The goal of DAG-TM is to enhance user flexibility/efficiency and increase system capacity, without adversely affecting system safety or restricting user accessibility to the National Airspace System (NAS). DAG-TM will be accomplished with a human-centered operational paradigm enabled by procedural and technological innovations. These innovations include automation aids, information sharing and Communication, Navigation, and Surveillance (CNS) / ATM technologies. The DAG-TM concept is intended to eliminate static restrictions to the maximum extent possible. In this paradigm, users may plan and operate according to their preferences - as the rule rather than the exception - with deviations occumng eyond the year 2015. Out of a total of 15 concept elements, 4 have been selected for initial sutidies (see Key Elements in sidebar). DAG-TM research is being performed at Ames, Glenn, and Langley Research Centers.

Up-conversion luminescence properties and energy transfer of Tm{sup 3+}/Yb{sup 3+} co-doped BaLa{sub 2}ZnO{sub 5}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie, Jing; Mei, Lefu, E-mail: mlf@cugb.edu.cn; Deng, Junru

2015-11-15

Tm{sup 3+}/Yb{sup 3+} co-doped BaLa{sub 2}ZnO{sub 5} up-conversion (UC) phosphors were successfully synthesized by high temperature solid-state reaction method. The X-ray diffraction (XRD) results show that synthesized phosphor co-doped with 0.75% Tm/10% Yb has the optimum pure phase of BaLa{sub 2}ZnO{sub 5} among different co-doping concentrations. The structure of BaLa{sub 2}ZnO{sub 5}:0.75% Tm/10% Yb phosphor was refined by the Rietveld method and results show the decreased unit cell parameters and cell volume after doping Tm{sup 3+}/Yb{sup 3+}, indicating that Tm{sup 3+}/Yb{sup 3+} have successfully replaced La{sup 3+}. Under excitation at 980 nm, Tm{sup 3+}/Yb{sup 3+} co-doped BaLa{sub 2}ZnO{sub 5} phosphorsmore » present bright blue emission near 478 nm generated by the {sup 1}G{sub 4}→{sup 3}H{sub 6} transition and weak red emissions around 653 nm and 692 nm generated by the {sup 1}G{sub 4}→{sup 3}F{sub 4} and {sup 3}F{sub 3}→{sup 3}H{sub 6} transitions of Tm{sup 3+}, respectively. The UC luminescence properties of BaLa{sub 2}ZnO{sub 5} phosphors co-doped with different Tm{sup 3+}/Yb{sup 3+} concentrations were investigated, and the related UC mechanisms of Tm{sup 3+}/Yb{sup 3+} co-doped BaLa{sub 2}ZnO{sub 5} depending on pump power were studied in detail. - Graphical abstract: Up-conversion luminescence of BaLa{sub 2}ZnO{sub 5}:Tm{sup 3+}/Yb{sup 3+} and its crystal structure and up-conversion mechanisms. - Highlights: • Up-conversion phosphors BaLa{sub 2}ZnO{sub 5} co-doped with Tm{sup 3+}/Yb{sup 3+} were synthesized by high temperature solid-state reaction method. • The crystal structure of BaLa{sub 2}ZnO{sub 5} and the changes of cell parameters and volume of BaLa{sub 2}ZnO{sub 5} after doping Tm{sup 3+} and Yb{sup 3+} have been discussed. • Up-conversion luminescence properties and energy transfer between Tm{sup 3+} and Yb{sup 3+} in BaLa{sub 2}ZnO{sub 5} have been discussed in detail.« less

Enhanced near-infrared photocatalysis of NaYF4:Yb, Tm/CdS/TiO2 composites.

PubMed

Guo, Xingyuan; Di, Weihua; Chen, Changfeng; Liu, Chunxu; Wang, Xue; Qin, Weiping

2014-01-21

The previous works by our group (Chem. Commun., 2010, 46, 2304-2306; ACS Catal., 2013, 3, 405-412; Phys. Chem. Chem. Phys., 2013, 15, 14681-14688) have reported the near-infrared-driven photocatalysis of broadband semiconductor TiO2 or ZnO that was combined with upconverting luminescence particles to form a core-shell structure. However, the photocatalytic efficiency is low for this new type of photocatalysts. In this work, NaYF4:Yb,Tm/CdS/TiO2 composites for NIR photocatalysis were prepared by linking CdS and TiO2 nanocrystals on the NaYF4:Yb,Tm microcrystal surfaces. CdS and TiO2 were well interacted to form a heterojunction structure. The energy transfer between NaYF4:Yb,Tm and the semiconductors CdS and TiO2 was investigated by steady-state and dynamic fluorescence spectroscopy. The photocatalytic activities of the as-prepared composites were evaluated by the degradation of methylene blue in aqueous solution upon NIR irradiation. Significantly, it was found that the united adhesions of CdS and TiO2 on the NaYF4:Yb,Tm particle surfaces showed much higher catalytic activities than the individual adhesion of CdS or TiO2 on the NaYF4:Yb,Tm surfaces. This was attributed mainly to the effective separation of the photogenerated electron-hole pairs due to the charge transfer across the CdS-TiO2 interface driven by the band potential difference between them. The presented composite structure of upconverting luminescence materials coupled with narrow/wide semiconductor heterojunctions provides a new model for improved NIR photocatalysis.

BOREAS RSS-15 SIR-C and Landsat TM Biomass and Landcover Maps of the NSA

NASA Technical Reports Server (NTRS)

Hall, Forrest G. (Editor); Nickeson, Jaime (Editor); Ranson, K. Jon

2000-01-01

As part of BOREAS, the RSS-15 team conducted an investigation using SIR-C, X-SAR, and Landsat TM data for estimating total above-ground dry biomass for the SSA and NSA modeling grids and component biomass for the SSA. Relationships of backscatter to total biomass and total biomass to foliage, branch, and bole biomass were used to estimate biomass density across the landscape. The procedure involved image classification with SAR and Landsat TM data and development of simple mapping techniques using combinations of SAR channels. For the SSA, the SIR-C data used were acquired on 06-Oct-1994, and the Landsat TM data used were acquired on 02-Sep-1995. The maps of the NSA were developed from SIR-C data acquired on 13-Apr-1994. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

F-200(TM): The new solution for fire protection

NASA Technical Reports Server (NTRS)

Thornton, Alfred J.; Walter, Gerald J.