Sample records for national biosecurity approaches

  1. Implementing biosecurity education: approaches, resources and programmes.

    PubMed

    Minehata, Masamichi; Sture, Judi; Shinomiya, Nariyoshi; Whitby, Simon

    2013-12-01

    This paper aims to present possible approaches, resources and programmes to introduce the topic of biosecurity to life scientists and engineers at the higher education level. Firstly, we summarise key findings from a number of international surveys on biosecurity education that have been carried out in the United States, Europe, Israel and the Asia-Pacific region. Secondly, we describe the development of our openly-accessible education resource, illustrating the scope and content of these materials. Thirdly, we report on actual cases of biosecurity education that have been implemented. These include achievements in and lessons derived from the implementation of biosecurity education at the National Defense Medical College in Japan. These experiences are followed by presentation of the expert-level "Train-the-Trainer" programmes subsequently launched by the University of Bradford in the United Kingdom. These examples will help readers to understand how educators can enhance their own understanding about biosecurity issues and how they can then disseminate their knowledge through development of their own customised, relevantly-targeted and stage-tailored education programmes within their own life science communities. By providing these examples, we argue that education for life scientists, policy-makers and other stakeholders about social responsibility on dual-use issues is easily achievable and need not be expensive, time-consuming or over-burdening. We suggest that recurring classes or courses be held at appropriate times during educational programmes to accommodate the developing expertise and advancing learning stages of students.

  2. Implementing Biosecurity Education: Approaches, Resources and Programmes

    PubMed Central

    Minehata, Masamichi; Sture, Judi; Shinomiya, Nariyoshi; Whitby, Simon

    2016-01-01

    This paper aims to present possible approaches, resources and programmes to introduce the topic of biosecurity to life scientists and engineers at the higher education level. Firstly, we summarise key findings from a number of international surveys on biosecurity education that have been carried out in the United States, Europe, Israel and the Asia–Pacific region. Secondly, we describe the development of our openly-accessible education resource, illustrating the scope and content of these materials. Thirdly, we report on actual cases of biosecurity education that have been implemented. These include achievements in and lessons derived from the implementation of biosecurity education at the National Defense Medical College in Japan. These experiences are followed by presentation of the expert-level “Train-the-Trainer” programmes subsequently launched by the University of Bradford in the United Kingdom. These examples will help readers to understand how educators can enhance their own understanding about biosecurity issues and how they can then disseminate their knowledge through development of their own customised, relevantly-targeted and stage-tailored education programmes within their own life science communities. By providing these examples, we argue that education for life scientists, policy-makers and other stakeholders about social responsibility on dual-use issues is easily achievable and need not be expensive, time-consuming or over-burdening. We suggest that recurring classes or courses be held at appropriate times during educational programmes to accommodate the developing expertise and advancing learning stages of students. PMID:22038099

  3. Agricultural biosecurity.

    PubMed

    Waage, J K; Mumford, J D

    2008-02-27

    The prevention and control of new pest and disease introductions is an agricultural challenge which is attracting growing public interest. This interest is in part driven by an impression that the threat is increasing, but there has been little analysis of the changing rates of biosecurity threat, and existing evidence is equivocal. Traditional biosecurity systems for animals and plants differ substantially but are beginning to converge. Bio-economic modelling of risk will be a valuable tool in guiding the allocation of limited resources for biosecurity. The future of prevention and management systems will be strongly influenced by new technology and the growing role of the private sector. Overall, today's biosecurity systems are challenged by changing national priorities regarding trade, by new concerns about environmental effects of biological invasions and by the question 'who pays?'. Tomorrow's systems may need to be quite different to be effective. We suggest three changes: an integration of plant and animal biosecurity around a common, proactive, risk-based approach; a greater focus on international cooperation to deal with threats at source; and a commitment to refocus biosecurity on building resilience to invasion into agroecosystems rather than building walls around them.

  4. Adaptive approaches to biosecurity governance.

    PubMed

    Cook, David C; Liu, Shuang; Murphy, Brendan; Lonsdale, W Mark

    2010-09-01

    This article discusses institutional changes that may facilitate an adaptive approach to biosecurity risk management where governance is viewed as a multidisciplinary, interactive experiment acknowledging uncertainty. Using the principles of adaptive governance, evolved from institutional theory, we explore how the concepts of lateral information flows, incentive alignment, and policy experimentation might shape Australia's invasive species defense mechanisms. We suggest design principles for biosecurity policies emphasizing overlapping complementary response capabilities and the sharing of invasive species risks via a polycentric system of governance. © 2010 Society for Risk Analysis

  5. Looking at the formulation of national biosecurity education action plans

    PubMed Central

    Sture, J.; Minehata, M.; Shinomiya, N.

    2015-01-01

    In order for states to be assured of their compliance with the requirements of the Biological and Toxin Weapons Convention, it is necessary that all those science and policy stakeholders working within that state should be aware of their responsibilities under the Convention. This can only be achieved through a comprehensive national biosecurity education programme. We propose that each state should produce a national biosecurity action plan, with accompanying resources and materials to achieve this. A number of resources are already available online to support states in this challenge. We present a model for a national biosecurity action plan and propose a number of ways in which this may be achieved. PMID:22606763

  6. A Systems Approach to Agricultural Biosecurity.

    PubMed

    Anand, Manish

    This article highlights the importance of systems approaches in addressing agricultural biosecurity threats. On the basis of documentary analysis and stakeholder interaction, a brief survey of agricultural biosecurity threats and vulnerabilities from global and Indian perspectives is provided, followed by an exploration of technological and institutional capabilities. Finally, a perspective on the agricultural disease diagnostic networks is provided, drawing instances from global developments. Technical barriers to agroterrorism are lower than those to human-targeted bioterrorism, and the sector is unique as even a very small disease outbreak could prompt international export restrictions. Key vulnerabilities in the agriculture sector stem from, among others, the structure of agricultural production; insufficient monitoring, surveillance, and controls systems at the borders and in the food chain; inefficient systems for reporting unusual occurrences and outbreaks of disease; and lack of sufficiently trained human resources capable of recognizing or treating transboundary pathogens and diseases. An assessment of technology and institutions pertaining to crop and animal protection management suggests certain gaps. Investment in developing new technologies for civilian application in agriculture, as well as for legitimate actions pertaining to defense, detection, protection, and prophylaxis, and in upgrading laboratory facilities can increase the agricultural sector's level of preparedness for outbreaks. To address potential threats and vulnerabilities of agroterrorism effectively requires the development of a comprehensive strategy and a combined, interagency approach, ideally on an international level. It is proposed that a systems-oriented approach for developing knowledge and innovation networks and strengthening skills and capacities would enable a more resilient agricultural biosecurity system.

  7. Why biosecurity matters: students' knowledge of biosecurity and implications for future engagement with biosecurity initiatives

    NASA Astrophysics Data System (ADS)

    Ram, Rajesh; France, Bev; Birdsall, Sally

    2016-01-01

    Background: Research on biosecurity is important as New Zealand's agricultural export-driven economy is susceptible to biosecurity threats. Because New Zealand is reliant on the primary industries to drive its economy, bovine diseases such as foot and mouth could have a devastating effect on the economy. Purpose: Making sure that the general public are aware of the importance of maintaining biosecurity is crucial in order to protect New Zealand's economy, human health, the environment, and social and cultural values. New Zealand Year 9 students' knowledge of biosecurity was gauged as these students represented the next generation of individuals tasked to maintain biosecurity in New Zealand. Design: A qualitative approach using the interpretive mode of inquiry was used to investigate the knowledge about biosecurity with New Zealand Year 9 students. Questionnaires and interviews were the data collection tools. Sample: One hundred and seventy-one students completed a questionnaire that consisted of Likert-type questions and open-ended questions. Nine students were interviewed about their knowledge. Results: The findings showed that New Zealand Year 9 students lacked specific knowledge about unwanted plants, animals and microorganisms. These students saw illicit drug plants as unwanted plants and mainly saw possums as unwanted animals in New Zealand. Their knowledge about unwanted microorganisms in New Zealand was dominated by human-disease-causing microbes. A lack of knowledge of biosecurity issues in New Zealand was seen as the major factor in these students limited understanding of biosecurity. Conclusions: Based on these findings, it can be said that knowledge of an issue is critical in enabling individuals to develop an understanding about biosecurity. Explicit teaching of biosecurity-related curriculum topics could provide New Zealand Year 9 students with an opportunity to develop knowledge about biosecurity in New Zealand.

  8. Biosecurity in Scandinavia.

    PubMed

    Bork, Kristian H; Halkjaer-Knudsen, Vibeke; Hansen, John-Erik Stig; Heegaard, Erik D

    2007-03-01

    This article investigates the extent to which biosecurity measures are recognized and have been implemented in the Nordic countries, in the absence of formalized security standards and legislation. Two trials were undertaken: first, a broad combined biosafety and biosecurity questionnaire survey of the Nordic countries, and, second, a focused on-site audit of 22 facilities, with 94 laboratories, in Denmark. Both trials indicated that external security had been partially implemented but that little attention had been paid to internal security and the establishment of biosecurity. It was demonstrated that the backgrounds and identities of insiders were rarely checked and that they could have gained access to both pathogen inventory lists and freezers in many facilities. In 81% of pathogen-containing facilities, pathogens were not routinely and centrally accounted for. The authors recommend the establishment of a legal framework congruent with international standards and obligations; novel governmental national biosecurity authorities, requiring a fusion of both microbiological and technical expertise and legislative powers; and the formulation of a new code of conduct termed "Good Biosecurity Practice."

  9. Species Delimitation and Global Biosecurity

    PubMed Central

    Boykin, Laura M.; Armstrong, Karen F.; Kubatko, Laura; De Barro, Paul

    2012-01-01

    Species delimitation directly impacts on global biosecurity. It is a critical element in the decisions made by national governments in regard to the flow of trade and to the biosecurity measures imposed to protect countries from the threat of invasive species. Here we outline a novel approach to species delimitation, “tip to root”, for two highly invasive insect pests, Bemisia tabaci (sweetpotato whitefly) and Lymantria dispar (Asian gypsy moth). Both species are of concern to biosecurity, but illustrate the extremes of phylogenetic resolution that present the most complex delimitation issues for biosecurity; B. tabaci having extremely high intra-specific genetic variability and L. dispar composed of relatively indistinct subspecies. This study tests a series of analytical options to determine their applicability as tools to provide more rigorous species delimitation measures and consequently more defensible species assignments and identification of unknowns for biosecurity. Data from established DNA barcode datasets (COI), which are becoming increasingly considered for adoption in biosecurity, were used here as an example. The analytical approaches included the commonly used Kimura two-parameter (K2P) inter-species distance plus four more stringent measures of taxon distinctiveness, (1) Rosenberg’s reciprocal monophyly, (P(AB)),1 (2) Rodrigo’s (P(randomly distinct)),2 (3) genealogical sorting index, (gsi),3 and (4) General mixed Yule-coalescent (GMYC).4,5 For both insect datasets, a comparative analysis of the methods revealed that the K2P distance method does not capture the same level of species distinctiveness revealed by the other three measures; in B. tabaci there are more distinct groups than previously identified using the K2P distances and for L. dipsar far less variation is apparent within the predefined subspecies. A consensus for the results from P(AB), P(randomly distinct) and gsi offers greater statistical confidence as to where genetic limits

  10. 77 FR 16846 - National Science Advisory Board for Biosecurity Meeting; Office of Biotechnology Activities...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-22

    ... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Science Advisory Board for Biosecurity Meeting; Office of Biotechnology Activities, Office of Science Policy, Office of..., as amended (5 U.S.C. App.), notice is hereby given of the following meeting of the National Science...

  11. Biosecurity Risk Assessment Methodology (BioRAM) v. 2.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    CASKEY, SUSAN; GAUDIOSO, JENNIFER; SALERNO, REYNOLDS

    Sandia National Laboratories International Biological Threat Reduction Dept (SNL/IBTR) has an ongoing mission to enhance biosecurity assessment methodologies, tools, and guise. These will aid labs seeking to implement biosecurity as advocated in the recently released WHO's Biorisk Management: Lab Biosecurity Guidance. BioRAM 2.0 is the software tool developed initially using the SNL LDRD process and designed to complement the "Laboratory Biosecurity Risk Handbook" written by Ren Salerno and Jennifer Gaudioso defining biosecurity risk assessment methodologies.

  12. Strengthening Biosecurity in Iraq: Development of a National Biorisk Management System

    PubMed Central

    Al Jewari, Mahdi F. H.; Koblentz, Gregory D.

    2016-01-01

    Since 2004, the Republic of Iraq has undertaken a concerted effort to comply with all of its international obligations to prevent the proliferation and the use of chemical, biological, radiological, and nuclear (CBRN) weapons. A centerpiece of this effort is Iraq’s development of a National Biorisk Management System. The Iraqi National Monitoring Authority (INMA), which is responsible for CBRN security and non-proliferation in Iraq, has played a key role in establishing this system. This article provides an overview of Iraq’s international non-proliferation commitments, describes the legal and organizational steps it has taken to implement these commitments, and examines current initiatives to strengthen Iraq’s biosecurity. PMID:26952002

  13. Exploring the role of small-scale livestock keepers for national biosecurity-The pig case.

    PubMed

    Correia-Gomes, Carla; Henry, Madeleine K; Auty, Harriet K; Gunn, George J

    2017-09-15

    Small-scale keepers are less likely to engage with production organisations and may therefore be less aware of legislation, rules and biosecurity practices which are implemented in the livestock sector. Their role in the transmission of endemic and exotic diseases is not well studied, but is believed to be important. The authors use small-scale pig keepers in Scotland as an example of how important small-scale livestock keepers might be for national biosecurity. In Scotland more than two thirds of pig producers report that they keep less than 10 pigs, meaning that biosecurity practices and pig health status on a substantial number of holdings are largely unknown; it is considered important to fill this knowledge gap. A questionnaire was designed and implemented in order to gather some of this information. The questionnaire comprised a total of 37 questions divided into seven sections (location of the enterprise, interest in pigs, details about the pig enterprise, marketing of pigs, transport of pigs, pig husbandry, and pig health/biosecurity). Over 610 questionnaires were sent through the post and the questionnaire was also available online. The questionnaire was implemented from June to October 2013 and 135 questionnaires were returned by target respondents. The responses for each question are discussed in detail in this paper. Overall, our results suggest that the level of disease identified by small-scale pig keepers is low but the majority of the small-scale pig keepers are mixed farms, with associated increased risk for disease transmission between species. Almost all respondents implemented at least one biosecurity measure, although the measures taken were not comprehensive in the majority of cases. Overall as interaction between small-scale keepers and commercial producers exists in Scotland the former can pose a risk for commercial production. This investigation fills gaps in knowledge which will allow industry stakeholders and policy makers to adapt their

  14. A Biosecurity Survey in Kenya, November 2014 to February 2015.

    PubMed

    Ndhine, Edwardina Otieno; Slotved, Hans-Christian; Osoro, Eric Mogaka; Olsen, Katja N; Rugutt, Moses; Wanjohi, Cathryn W; Mwanda, Walter; Kinyagia, Benson Mburu; Steenhard, Nina R; Hansen, John-Erik Stig

    2016-01-01

    A biosecurity survey was performed to gather information on the biosecurity level and laboratory capacity in Kenya for the purpose of providing information outlining relevant components for biosecurity legislation, biosecurity implementation, and enforcement of biosecurity measures in Kenya. This survey is, to the authors' knowledge, the first to be published from an African country. A total of 86 facilities with laboratories covering relevant categories, such as training laboratories, human diagnostic laboratories, veterinary diagnostic laboratories, and research laboratories, were selected to participate in the survey. Each facility was visited by a survey team and staff were asked to answer 29 groups of questions from a questionnaire. The survey showed that Kenyan laboratory facilities contain biological agents of biosecurity concern. The restrictions for these agents were found to be limited for several of the facilities, in that many laboratory facilities and storage units were open for access by either students or staff who had no need of access to the laboratory. The survey showed a great deal of confusion in the terms biosecurity and biosafety and a generally limited biosecurity awareness among laboratory personnel. The survey showed that the security of biological agents of biosecurity concern in many facilities does not meet the international requirements. The authors recommend developing a legal framework in Kenya for effective controls, including national biosecurity regulations, guidelines, and procedures, thereby reducing the risk that a Kenyan laboratory would be the source of a future biological attack.

  15. Why Biosecurity Matters: Students' Knowledge of Biosecurity and Implications for Future Engagement with Biosecurity Initiatives

    ERIC Educational Resources Information Center

    Ram, Rajesh; France, Bev; Birdsall, Sally

    2016-01-01

    Background: Research on biosecurity is important as New Zealand's agricultural export-driven economy is susceptible to biosecurity threats. Because New Zealand is reliant on the primary industries to drive its economy, bovine diseases such as foot and mouth could have a devastating effect on the economy. Purpose: Making sure that the general…

  16. State-of-the-art in biosafety and biosecurity in European countries.

    PubMed

    Bielecka, Anna; Mohammadi, Ali Akbar

    2014-06-01

    The terms biosafety and biosecurity are widely used in different concepts and refer not only to protection of human beings and their surrounding environment against hazardous biological agent, but also to global disarmament of weapons of mass destruction. As a result, the biosafety and biosecurity issues should be considered interdisciplinary based on multilateral agreements against proliferation of biological weapons, public health and environmental protection. This publication presents information on both, international and national biosafety and biosecurity legislation. Status of national implementation of the Biological and Toxin Weapons Convention, penalization issues and measures to account for and secure production, use, storage of particularly dangerous pathogens or activities involving humans, plants and animals where infection may pose a risk have been analyzed. Safety and security measures in laboratories have been studied. Moreover, dual-use technology and measures of secure transport of biohazard materials have been also taken into account. In addition, genetic engineering regulations, biosecurity activities in laboratories and code of conducts have been investigated, as well.

  17. From biodefence to biosecurity: the Obama administration's strategy for countering biological threats.

    PubMed

    Koblentz, Gregory D

    2012-01-01

    The Seventh Review Conference of the Biological Weapons Convention (BWC), the first international treaty to outlaw an entire class of weapons, was held in Geneva in December 2011. On 7 December, Secretary of State Hillary Clinton became the highest-ranking US government official to address a BWC meeting. Secretary Clinton told the assembled delegation that ‘we view the risk of bioweapons attack as both a serious national security challenge and a foreign policy priority’. At the same time, she warned that a large-scale disease outbreak ‘could cripple an already fragile global economy’. Secretary Clinton's speech reflected a new understanding that the range of biological threats to international security has expanded from state-sponsored biological warfare programmes to include biological terrorism, dual-use research and naturally occurring infectious diseases such as pandemics. Recognizing these changes, President Barack Obama released a new national strategy for countering biological threats in 2009. This strategy represents a shift in thinking away from the George W. Bush administration's focus on biodefence, which emphasized preparing for and responding to biological weapon attacks, to the concept of biosecurity, which includes measures to prevent, prepare for and respond to naturally occurring and man-made biological threats. The Obama administration's biosecurity strategy seeks to reduce the global risk of naturally occurring and deliberate disease outbreaks through prevention, international cooperation, and maximizing synergies between health and security. The biosecurity strategy is closely aligned with the Obama administration's broader approach to foreign policy, which emphasizes the pragmatic use of smart power, multilateralism and engagement to further the national interest. This article describes the Obama administration's biosecurity strategy; highlights elements of continuity and change from the policies of the Bush administration; discusses

  18. "Catch 22": Biosecurity awareness, interpretation and practice amongst poultry catchers.

    PubMed

    Millman, Caroline; Christley, Rob; Rigby, Dan; Dennis, Diana; O'Brien, Sarah J; Williams, Nicola

    2017-06-01

    Campylobacter contamination of chicken on sale in the UK remains at high levels and has a substantial public health impact. This has prompted the application of many interventions in the supply chain, including enhanced biosecurity measures on-farm. Catching and thinning are acknowledged as threats to the maintenance of good biosecurity, yet the people employed to undertake this critical work (i.e. 'catchers') are a rarely studied group. This study uses a mixed methods approach to investigate catchers' (n=53) understanding of the biosecurity threats posed by the catching and thinning, and the barriers to good biosecurity practice. It interrogated the role of training in both the awareness and practice of good biosecurity. Awareness of lapses in biosecurity was assessed using a Watch-&-Click hazard awareness survey (n=53). Qualitative interviews (n=49 catchers, 5 farm managers) explored the understanding, experience and practice of catching and biosecurity. All of the catchers who took part in the Watch-&-Click study identified at least one of the biosecurity threats with 40% detecting all of the hazards. Those who had undergone training were significantly more likely to identify specific biosecurity threats and have a higher awareness score overall (48% compared to 9%, p=0.03). Crucially, the individual and group interviews revealed the tensions between the high levels of biosecurity awareness evident from the survey and the reality of the routine practice of catching and thinning. Time pressures and a lack of equipment rather than a lack of knowledge appear a more fundamental cause of catcher-related biosecurity lapses. Our results reveal that catchers find themselves in a 'catch-22' situation in which mutually conflicting circumstances prevent simultaneous completion of their job and compliance with biosecurity standards. 3 Hence, although education about, and enforcement of, biosecurity protocols has been recommended, our findings suggest that further reforms

  19. One-health approach as counter-measure against "autoimmune" responses in biosecurity.

    PubMed

    Mutsaers, Inge

    2015-03-01

    This Swine flu pandemic of 2009 and the potential Avian flu threat of 2011-2012 have revived a most challenging debate on protection against infectious diseases. The response to the Swine flu pandemic has been ambivalent, both on the societal (political) and the scientific level. While some scientists warned against potential massive loss of human lives and urged for immediate and large-scale vaccination, others accused them of unnecessary scaremongering, arguing that the pandemic would not be that severe. The lab-created virulent Avian flu virus - which has been created in order to 'fight' a potential Avian flu pandemic - sparked a fierce debate on the dual-use risks of such a pre-emptive strategy. This article involves an analysis of the medical-political response to these recent viral threats using Peter Sloterdijk's immunological framework as diagnostic tool. In his trilogy Spheres Sloterdijk uses immunological concepts to analyse and assess the contemporary biopolitical situation. It shows how drawing a parallel between the functioning of the biological immune system and "immune responses" on socio-political level enables to assess and reconceptualise biosecurity. It demonstrates that ideas such as "nature is the biggest terrorist" - as advanced by many virologists - sometimes result in exaggerated "immunisation responses". This strong defensive attitude sometimes brings about collateral damage. In other words, fierce biosecurity measures sometimes risk developing into "autoimmune" responses that actually destruct the body politic they are meant to protect. By drawing on recent insights in the functioning of the biological immune system it is shown how a One-Health approach that incorporates a broader and nuanced "immunological" repertoire could act as counter-measure against "autoimmune" responses in biosecurity. Copyright © 2014 Elsevier Ltd. All rights reserved.

  20. Auditing laboratory rodent biosecurity programs.

    PubMed

    Porter, William P; Horn, Mandy J; Cooper, Dale M; Klein, Hilton J

    2013-10-22

    A rodent biosecurity program that includes periodic evaluation of procedures used in an institution's vivarium can be used to ensure that best practices are in place to prevent a microbial pathogen outbreak. As a result of an ongoing comprehensive biosecurity review within their North American and European production facilities, the authors developed a novel biosecurity auditing process and worksheet that could be useful in other animal care and use operations. The authors encourage other institutions to consider initiating similar audits of their biosecurity programs to protect the health of their laboratory animals.

  1. Biosecurity strategies for conserving valuable livestock genetic resources.

    PubMed

    Wrathall, Anthony E; Simmons, Hugh A; Bowles, Dianna J; Jones, Sam

    2004-01-01

    The foot and mouth disease (FMD) epidemic in the UK in 2001 highlighted the threat of infectious diseases to rare and valuable livestock and stimulated a renewed interest in biosecurity and conservation. However, not all diseases resemble FMD: their transmission routes and pathological effects vary greatly, so biosecurity strategies must take this into account. Realism is also needed as to which diseases to exclude and which will have to be tolerated. The aim should be to minimise disease generally and to exclude those diseases that threaten the existence of livestock or preclude their national or international movement. Achieving this requires a team effort, bearing in mind the livestock species involved, the farming system ('open' or 'closed') and the premises. Effective biosecurity demands that practically every aspect of farm life is controlled, including movements of people, vehicles, equipment, food, manure, animal carcasses and wildlife. Above all, biosecurity strategies must cover the disease risks associated with moving the livestock themselves and this will require quarantine if adult or juvenile animals are imported into the herd or flock. The present paper emphasises the important role that reproductive technologies, such as artificial insemination and embryo transfer, can have in biosecurity strategies because they offer much safer ways for getting new genetic materials into herds/flocks than bringing in live animals. Embryo transfer is especially safe when the sanitary protocols promoted by the International Embryo Transfer Society and advocated by the Office International des Epizooties (the 'World Organisation for Animal Health') are used. Embryo transfer can also allow the full genetic complement to be salvaged from infected animals. Cryobanking of genetic materials, especially embryos, is another valuable biosecurity strategy because it enables their storage for conservation in the face of contingencies, such as epidemic disease and other

  2. Danish dairy farmers' perception of biosecurity.

    PubMed

    Kristensen, Erling; Jakobsen, Esben B

    2011-05-01

    To implement biosecurity measures at farm-level is a motivational challenge to dairy farmers as emerging diseases and their consequences largely are unpredictable. One of the reasons for this challenge is that outcomes are more likely to benefit society than the individual farmer. From the individual farmer's point of view the impacts of zoonotic risk, international trade and welfare concerns appear less obvious than the direct costs at farm-level. Consequently, a social dilemma may arise where collective interests are at odds with private interests. To improve biosecurity at farm-level farmers must be motivated to change behavior in the 'right' direction which could provide selfish farmers with unintended possibilities to exploit the level of biosecurity provided by other dairy farmers' collective actions. Farmers' perception of risk of disease introduction into a dairy herd was explored by means of Q-methodology. Participating farmers owned very large dairy herds and were selected for this study because Danish legislation since 2008 has required that larger farms develop and implement a farm specific biosecurity plan. However, a year from introduction of this requirement, none of the participating farmers had developed a biosecurity plan. Farmers' perception of biosecurity could meaningfully be described by four families of perspectives, labeled: cooperatives; confused; defectors, and introvert. Interestingly, all families of perspectives agreed that sourcing of animals from established dealers represented the highest risk to biosecurity at farm-level. Farmers and policy-makers are faced with important questions about biosecurity at farm-level related to the sanctioning system within the contextual framework of social dilemmas. To solve these challenges we propose the development of a market-mediated system to (1) reduce the risk of free-riders, and (2) provide farmers with incentives to improve biosecurity at farm-level. Copyright © 2011 Elsevier B.V. All

  3. Application of multiple behaviour change models to identify determinants of farmers' biosecurity attitudes and behaviours.

    PubMed

    Richens, I F; Houdmont, J; Wapenaar, W; Shortall, O; Kaler, J; O'Connor, H; Brennan, M L

    2018-07-01

    It has been recognised that few cattle farmers undertake biosecurity practices on their farms. Approaches that take into consideration individuals' preparedness for change, alongside beliefs thought to motivate the enactment of certain behaviours, may provide a framework for actuating tangible change. The aim of this study was to use a combination of behaviour change models to link beliefs with behaviour and identify possible key interventions to improve the uptake of biosecurity measures by dairy cattle farmers in Great Britain (GB). This is the first study to explore farmers' practices and attitudes in relation to the prevention of direct (animal to animal contact); indirect (via fomites); and other biosecurity measures using a multitheory approach. A cross-sectional study was carried out, with postal questionnaires sent to 2505 dairy cattle farmers. Questions were asked about the extent to which a host of biosecurity measures were used, the influence of various stakeholders (e.g. veterinarians, industry bodies) in informing biosecurity choices, and the perceived control farmers felt they had over biosecurity on their farms. Farmer attitudes towards biosecurity were also explored. Two behaviour change models, the Transtheoretical Model, and the Theory of Planned Behaviour, were utilised. A variety of analysis methods were used to interrogate the data, including multivariable logistic regression. A total of 908/2505 (36.2%) farmers responded, with 757 responses (30.2%) deemed eligible for inclusion. Farmers generally fell into one of two categories: those that reported not applying biosecurity measures with no intention of doing so in the future, and those that reported undertaking biosecurity measures for some time. Farmers felt that biosecurity improved cattle health and welfare, but also felt that disease was inevitable. More farmers agreed with statements relating to their ability to control, rather than prevent disease. Analysis suggested a difference between

  4. Issues in biosecurity and biosafety.

    PubMed

    Nordmann, Brian D

    2010-11-01

    The role of non-governmental organisations and other interested observers - civil society - has long been neglected by governments in the quest for a world secure from the threat of biological weapons or bioterrorism. New trends illustrate a greater appreciation of a strong need for a cooperative partnership. Governments need to accept and embrace some of these new trends and new technologies. At least since 2001 and the Amerithrax anthrax letters, the USA has had a significant focus on biosecurity and the related subject of biosafety. Biosecurity has also been raised to a place of prominence in security discussions throughout much of the rest of the globe, largely through the mechanisms of the Biological and Toxin Weapons Convention and related groups, but also through the World Health Organization and the implementation of the International Health Regulations, which is scheduled for 2012. Despite this attention, a clear understanding of the meanings of biosecurity and biosafety has yet to be achieved. Partly because of this lack of definition, and largely because of a broader understanding of the capabilities of the life sciences, many topics have begun to fall under the heading of biosecurity. This paper will not be able to explore all of these new topics but will instead attempt to present an overview of some of the issues at play today in the biosecurity dialogue. Published by Elsevier B.V.

  5. Biosafety and Biosecurity in European Containment Level 3 Laboratories: Focus on French Recent Progress and Essential Requirements.

    PubMed

    Pastorino, Boris; de Lamballerie, Xavier; Charrel, Rémi

    2017-01-01

    Even if European Union (EU) Member States are obliged to implement EU Directives 2000/54/EC on the protection of workers from risks related to exposure to biological agents at work , national biosafety regulations and practices varied from country to country. In fact, EU legislation on biological agents and genetically modified microorganisms is often not specific enough to ensure harmonization leading to difficulties in implementation for most laboratories. In the same way, biosecurity is a relatively new concept and a few EU Member States are known to have introduced national laboratory biosecurity legislation. In France, recent regulations have reinforced biosafety/biosecurity in containment level 3 (CL-3) laboratories but they concern a specific list of pathogens with no correlation in other European Members States. The objective of this review was to summarize European biosafety/biosecurity measures concerning CL-3 facilities focusing on French specificities. Essential requirements needed to preserve efficient biosafety measures when manipulating risk group 3 biological agents are highlighted. In addition, International, European and French standards related to containment laboratory planning, operation or biosafety equipment are described to clarify optimal biosafety and biosecurity requirements.

  6. Biosafety and Biosecurity in European Containment Level 3 Laboratories: Focus on French Recent Progress and Essential Requirements

    PubMed Central

    Pastorino, Boris; de Lamballerie, Xavier; Charrel, Rémi

    2017-01-01

    Even if European Union (EU) Member States are obliged to implement EU Directives 2000/54/EC on the protection of workers from risks related to exposure to biological agents at work, national biosafety regulations and practices varied from country to country. In fact, EU legislation on biological agents and genetically modified microorganisms is often not specific enough to ensure harmonization leading to difficulties in implementation for most laboratories. In the same way, biosecurity is a relatively new concept and a few EU Member States are known to have introduced national laboratory biosecurity legislation. In France, recent regulations have reinforced biosafety/biosecurity in containment level 3 (CL-3) laboratories but they concern a specific list of pathogens with no correlation in other European Members States. The objective of this review was to summarize European biosafety/biosecurity measures concerning CL-3 facilities focusing on French specificities. Essential requirements needed to preserve efficient biosafety measures when manipulating risk group 3 biological agents are highlighted. In addition, International, European and French standards related to containment laboratory planning, operation or biosafety equipment are described to clarify optimal biosafety and biosecurity requirements. PMID:28620600

  7. Evaluation of external biosecurity practices on southern Ontario sow farms.

    PubMed

    Bottoms, Kate; Poljak, Zvonimir; Dewey, Cate; Deardon, Rob; Holtkamp, Derald; Friendship, Robert

    2013-04-01

    External biosecurity protocols, aimed at preventing the introduction of new pathogens to the farm environment, are becoming increasingly important in the swine industry. Although assessments at the individual farm level occur regularly, efforts to cluster swine herds into meaningful biosecurity groups and to summarize this information at the regional level are relatively infrequent. The objectives of this study were: (i) to summarize external biosecurity practices on sow farms in southern Ontario; (ii) to cluster these farms into discrete biosecurity groups and to describe their characteristics, the variables of importance in differentiating between these groups, and their geographic distribution; and (iii) to identify significant predictors of biosecurity group membership. Data were collected using the Production Animal Disease Risk Assessment Program's Survey for the Breeding Herd. A subset of variables pertaining to external biosecurity practices was selected for two-step cluster analysis, which resulted in 3 discrete biosecurity groups. These groups were named by the authors as: (i) high biosecurity herds that were open with respect to replacement animals, (ii) high biosecurity herds that were closed with respect to replacement animals, and (iii) low biosecurity herds. Variables pertaining to trucking practices and the source of replacement animals were the most important in differentiating between these groups. Multinomial logistic regression provided insight into which demographic and neighborhood variables serve as significant predictors of biosecurity group membership (p<0.05). Variables in the final regression model include: herd density within a 4.8 km radius, number of sows on the premises, and site production type. The odds of belonging to the high biosecurity group that was open with respect to replacement animals, relative to the low biosecurity group, increased 1.001 times for each additional sow (p=0.001). The odds of belonging to the high

  8. Biosecurity measures for backyard poultry in developing countries: a systematic review

    PubMed Central

    2012-01-01

    Background Poultry represents an important sector in animal production, with backyard flocks representing a huge majority, especially in the developing countries. In these countries, villagers raise poultry to meet household food demands and as additional sources of incomes. Backyard production methods imply low biosecurity measures and high risk of infectious diseases, such as Newcastle disease or zoonosis such as Highly Pathogenic Avian Influenza (HPAI). We reviewed literature on biosecurity practices for prevention of infectious diseases, and published recommendations for backyard poultry and assessed evidence of their impact and feasibility, particularly in developing countries. Documents were sourced from the Food and Agriculture Organization (FAO) website, and from Pubmed and Google databases. Results A total of 62 peer-reviewed and non-referred documents were found, most of which were published recently (after 2004) and focused on HPAI/H5N1-related biosecurity measures (64%). Recommendations addressed measures for flock management, feed and water management, poultry trade and stock change, poultry health management and the risk to humans. Only one general guideline was found for backyard poultry-related biosecurity; the other documents were drawn up for specific developing settings and only engaged their authors (e.g. consultants). These national guidelines written by consultants generated recommendations regarding measures derived from the highest standards of commercial poultry production. Although biosecurity principles of isolation and containment are described in most documents, only a few documents were found on the impact of measures in family poultry settings and none gave any evidence of their feasibility and effectiveness for backyard poultry. Conclusions Given the persistent threat posed by HPAI/H5N1 to humans in developing countries, our findings highlight the importance of encouraging applied research toward identifying sustained and adapted

  9. An assessment of external biosecurity on Southern Ontario swine farms and its application to surveillance on a geographic level.

    PubMed

    Bottoms, Kate; Poljak, Zvonimir; Friendship, Robert; Deardon, Rob; Alsop, Janet; Dewey, Cate

    2013-10-01

    Risk-based surveillance is becoming increasingly important in the veterinary and public health fields. It serves as a means of increasing surveillance sensitivity and improving cost-effectiveness in an increasingly resource-limited environment. Our approach for developing a tool for the risk-based geographical surveillance of contagious diseases of swine incorporates information about animal density and external biosecurity practices within swine herds in southern Ontario. The objectives of this study were to group the sample of herds into discrete biosecurity groups, to develop a map of southern Ontario that can be used as a tool in the risk-based geographical surveillance of contagious swine diseases, and to identify significant predictors of biosecurity group membership. A subset of external biosecurity variables was selected for 2-step cluster analysis and latent class analysis (LCA). It was determined that 4 was the best number of groups to describe the data, using both analytical approaches. The authors named these groups: i) high biosecurity herds that were open with respect to replacement animals; ii) high biosecurity herds that were closed with respect to replacement animals; iii) moderate biosecurity herds; and iv) low biosecurity herds. The risk map was developed using information about the geographic distribution of herds in the biosecurity groups, as well as the density of swine sites and of grower-finisher pigs in the study region. Finally, multinomial logistic regression identified heat production units (HPUs), number of incoming pig shipments per month, and herd type as significant predictors of biosecurity group membership. It was concluded that the ability to identify areas of high and low risk for disease may improve the success of surveillance and eradication projects.

  10. An assessment of external biosecurity on southern Ontario swine farms and its application to surveillance on a geographic level

    PubMed Central

    Bottoms, Kate; Poljak, Zvonimir; Friendship, Robert; Deardon, Rob; Alsop, Janet; Dewey, Cate

    2013-01-01

    Risk-based surveillance is becoming increasingly important in the veterinary and public health fields. It serves as a means of increasing surveillance sensitivity and improving cost-effectiveness in an increasingly resource-limited environment. Our approach for developing a tool for the risk-based geographical surveillance of contagious diseases of swine incorporates information about animal density and external biosecurity practices within swine herds in southern Ontario. The objectives of this study were to group the sample of herds into discrete biosecurity groups, to develop a map of southern Ontario that can be used as a tool in the risk-based geographical surveillance of contagious swine diseases, and to identify significant predictors of biosecurity group membership. A subset of external biosecurity variables was selected for 2-step cluster analysis and latent class analysis (LCA). It was determined that 4 was the best number of groups to describe the data, using both analytical approaches. The authors named these groups: i) high biosecurity herds that were open with respect to replacement animals; ii) high biosecurity herds that were closed with respect to replacement animals; iii) moderate biosecurity herds; and iv) low biosecurity herds. The risk map was developed using information about the geographic distribution of herds in the biosecurity groups, as well as the density of swine sites and of grower-finisher pigs in the study region. Finally, multinomial logistic regression identified heat production units (HPUs), number of incoming pig shipments per month, and herd type as significant predictors of biosecurity group membership. It was concluded that the ability to identify areas of high and low risk for disease may improve the success of surveillance and eradication projects. PMID:24124266

  11. Biosafety and biosecurity as essential pillars of international health security and cross-cutting elements of biological nonproliferation

    PubMed Central

    2010-01-01

    The critical aspects of biosafety, biosecurity, and biocontainment have been in the spotlight in recent years. There have also been increased international efforts to improve awareness of modern practices and concerns with regard to the safe pursuit of life sciences research, and to optimize current oversight frameworks, thereby resulting in decreased risk of terrorist/malevolent acquisition of deadly pathogens or accidental release of a biological agent, and increased safety of laboratory workers. Our purpose is to highlight how the World Health Organization’s (WHO) revised International Health Regulations (IHR[2005]), the Biological Weapons Convention (BWC), and the United Nations Security Council Resolution (UNSCR) 1540 overlap in their requirements with regard to biosafety and biosecurity in order to improve the understanding of practitioners and policymakers and maximize the use of national resources employed to comply with internationally-mandated requirements. The broad range of goals of these international instruments, which are linked by the common thread of biosafety and biosecurity, highlight their significance as essential pillars of international health security and cross-cutting elements of biological nonproliferation. The current efforts of the Republic of Georgia to enhance biosafety and biosecurity in accordance with these international instruments are summarized. PMID:21143822

  12. Mini-review: Assessing the drivers of ship biofouling management--aligning industry and biosecurity goals.

    PubMed

    Davidson, Ian; Scianni, Christopher; Hewitt, Chad; Everett, Richard; Holm, Eric; Tamburri, Mario; Ruiz, Gregory

    2016-01-01

    Biofouling exerts a frictional and cost penalty on ships and is a direct cause of invasion by marine species. These negative consequences provide a unifying purpose for the maritime industry and biosecurity managers to prevent biofouling accumulation and transfer, but important gaps exist between these sectors. This mini-review examines the approach to assessments of ship biofouling among sectors (industry, biosecurity and marine science) and the implications for existing and emerging management of biofouling. The primary distinctions between industry and biosecurity in assessment of vessels biofouling revolve around the resolution of biological information collected and the specific wetted surface areas of primary concern to each sector. The morphological characteristics of biofouling and their effects on propulsion dynamics are of primary concern to industry, with an almost exclusive focus on the vertical sides and flat bottom of hulls and an emphasis on antifouling and operational performance. In contrast, the identity, biogeography, and ecology of translocated organisms is of highest concern to invasion researchers and biosecurity managers and policymakers, especially as it relates to species with known histories of invasion elsewhere. Current management practices often provide adequate, although not complete, provision for hull surfaces, but niche areas are well known to enhance biosecurity risk. As regulations to prevent invasions emerge in this arena, there is a growing opportunity for industry, biosecurity and academic stakeholders to collaborate and harmonize efforts to assess and manage biofouling of ships that should lead to more comprehensive biofouling solutions that promote industry goals while reducing biosecurity risk and greenhouse gas emissions.

  13. Breaking the chain of zoonoses through biosecurity in livestock.

    PubMed

    Layton, Daniel S; Choudhary, Anupma; Bean, Andrew G D

    2017-10-20

    Increases in global travel, trade and urbanisation are leading to greater incidence of zoonotic disease, and livestock are often a key link in the spread of disease to humans. As such, livestock vaccination strategies, as a part of broader biosecurity solutions, are critical to both animal and human health. Importantly, approaches that restrict infectious agents in livestock, not only protects their economic value but should reduce the potential for spill over infections in humans. Biosecurity solutions to livestock health can take a number of different forms and are generally heavily weighted towards prevention of infection rather than treatment. Therefore, vaccination can provide an effective component of a strategic approach, particularly as production economics dictate the use of cost effective solutions. Furthermore, in an evolving global environment there is a need for vaccines that accommodate for lower socioeconomic and rapidly emerging zoonotics. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  14. The Australian quarantine and biosecurity legislation: Constitutionality and critique.

    PubMed

    Gray, Anthony

    2015-06-01

    Australia's quarantine and biosecurity laws have been in focus recently with the serious outbreak of the ebola virus and the not-so-serious incident involving an actor's dogs apparently gaining unauthorised access to Australia. These incidents have coincided with the move to replace Australia's existing quarantine legislation with a modern regulatory framework for managing biosecurity risks. This article critiques the existing and new Australian legislation, comparing them with approaches in other jurisdictions and discussing some relevant public policy issues. In particular, the article comments on the constitutionality of the provisions relating to the detention of individuals for public health reasons, such as to control or limit the spread of disease, finding the new legislation to be an improvement on the existing one.

  15. Bio-Security Proficiencies Project for Beginning Producers in 4-H

    ERIC Educational Resources Information Center

    Smith, Martin H.; Meehan, Cheryl L.; Borba, John A.

    2014-01-01

    Improving bio-security practices among 4-H members who raise and show project animals is important. Bio-security measures can reduce the risk of disease spread and mitigate potential health and economic risks of disease outbreaks involving animal and zoonotic pathogens. Survey data provided statistical evidence that the Bio-Security Proficiencies…

  16. Investigation of smallholder farmer biosecurity and implications for sustainable foot-and-mouth disease control in Cambodia.

    PubMed

    Young, J R; Suon, S; Olmo, L; Bun, C; Hok, C; Ashley, K; Bush, R D; Windsor, P A

    2017-12-01

    In Cambodia, the majority of the population is rural and reliant on subsistence agriculture, with cattle raised by smallholder farmers using traditional practices, resulting in low productivity and vulnerability to foot-and-mouth disease (FMD). As FMD causes deleterious impacts on rural livelihoods, known FMD risk factors were reviewed, using knowledge, attitudes and practice (KAP) surveys of smallholders (n = 240) from four regions. The study aimed to understand current biosecurity threats to smallholder livelihoods and investigate the hypothesis that smallholder farmers practising FMD risk management should be associated with higher incomes from cattle. Descriptive data were examined to demonstrate trends in KAP and a multivariable linear regression model developed to identify cattle income predictors. Results showed that baseline mean knowledge scores were low at 28.4% across all regions and basic biosecurity practices, including quarantine of new cattle, isolation of sick cattle and FMD vaccination, were lacking. As farmers purchase and sell cattle from and to various administration levels (including export), there is high risk of FMD transmission into and from smallholder communities. The final multivariable linear regression model identified significant explanatory parameters for annual cattle income, including region, number of calves born, forage plot size (ha), vaccination of cattle and the number of cattle purchased (F pr. < 0.001, R 2  = 29.9). Individual biosecurity practices including FMD vaccination were not significant predictors of income. With the current focus of farmers on treatment of FMD with inappropriate antibiotics leading to potential anti-microbial residue issues, yet receptivity to payment for vaccine in most regions, there is an urgent need for a coordinated national biosecurity and FMD management public awareness campaign. Further, to enhance the association between improved cattle health and rural livelihoods, it is recommended

  17. Biosecurity on Finnish cattle, pig and sheep farms - results from a questionnaire.

    PubMed

    Sahlström, Leena; Virtanen, Terhi; Kyyrö, Jonna; Lyytikäinen, Tapani

    2014-11-01

    Biosecurity is important in order to prevent disease transmission between animals on farms as well as from farm to farm. Personal biosecurity routines such as hand washing and the use of protective clothing and footwear are measures that should be used at all farms. Other measures are for example related to purchasing new animals to the farm. A questionnaire-based survey was undertaken to study the frequency of use of different biosecurity measures on cattle, pig and sheep farms in Finland. Information about which biosecurity measures are in use is needed for contingency planning of emerging diseases or when combating endemic diseases. Knowledge about the level of biosecurity of a farm is also needed in order to assess if and where improvement is needed. Information regarding biosecurity levels may benefit future animal disease risk assessments. A total of 2242 farmers responded to the questionnaire resulting in a response rate of 45%. The implementation frequencies of different biosecurity measures are reported. The results revealed differences between species: large pig farms had a better biosecurity level than small cattle farms. There were also differences between production types such as dairy farming versus beef cattle farming, but these were not as remarkable. Sheep farming in Finland is sparse and the large number of hobby farmers keeps the biosecurity level low on sheep farms. This might represent a risk for the entire sheep farming industry. The Finnish farmers were satisfied with their on-farm biosecurity. Eighty percent of the farmers report that they were satisfied even though the biosecurity level was not particularly high. The implementation of biosecurity measures could be further improved. Even though the disease situation in Finland is good today, one must be prepared for possible epidemics of threatening diseases. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Biosafety and biosecurity in veterinary laboratories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Finley, Melissa R.; Astuto-Gribble, Lisa M.; Brass, Van Hildren

    Here, with recent outbreaks of MERS-Cov, Anthrax, Nipah, and Highly Pathogenic Avian Influenza, much emphasis has been placed on rapid identification of infectious agents globally. As a result, laboratories are building capacity, conducting more advanced and sophisticated research, increasing laboratory staff, and establishing collections of dangerous pathogens in an attempt to reduce the impact of infectious disease outbreaks and characterize disease causing agents. With this expansion, the global laboratory community has started to focus on laboratory biosafety and biosecurity to prevent the accidental and/or intent ional release o f these agents. Laboratory biosafety and biosecurity systems are used around themore » world to help mit igate the risks posed by dangerous pathogens in the laboratory. Veterinary laboratories carry unique responsibilities to workers and communities to safely and securely handle disease causing microorganisms. Many microorganisms studied in veterinary laboratories not only infect animals, but also have the potential to infect humans. This paper will discuss the fundamentals of laboratory biosafety and biosecurity.« less

  19. Biosecurity and the review and publication of dual-use research of concern.

    PubMed

    Patrone, Daniel; Resnik, David; Chin, Lisa

    2012-09-01

    Dual-use research of concern (DURC) is scientific research with significant potential for generating information that could be used to harm national security, the public health, or the environment. Editors responsible for journal policies and publication decisions play a vital role in ensuring that effective safeguards exist to cope with the risks of publishing scientific research with dual-use implications. We conducted an online survey of 127 chief editors of life science journals in 27 countries to examine their attitudes toward and experience with the review and publication of dual-use research of concern. Very few editors (11) had experience with biosecurity review, and no editor in our study reported having ever refused a submission on biosecurity grounds. Most respondents (74.8%) agreed that editors have a responsibility to consider biosecurity risks during the review process, but little consensus existed among editors on how to handle specific issues in the review and publication of research with potential dual-use implications. More work is needed to establish consensus on standards for the review and publication of dual-use research of concern in life science journals.

  20. Biosecurity and the Review and Publication of Dual-Use Research of Concern

    PubMed Central

    Resnik, David; Chin, Lisa

    2012-01-01

    Dual-use research of concern (DURC) is scientific research with significant potential for generating information that could be used to harm national security, the public health, or the environment. Editors responsible for journal policies and publication decisions play a vital role in ensuring that effective safeguards exist to cope with the risks of publishing scientific research with dual-use implications. We conducted an online survey of 127 chief editors of life science journals in 27 countries to examine their attitudes toward and experience with the review and publication of dual-use research of concern. Very few editors (11) had experience with biosecurity review, and no editor in our study reported having ever refused a submission on biosecurity grounds. Most respondents (74.8%) agreed that editors have a responsibility to consider biosecurity risks during the review process, but little consensus existed among editors on how to handle specific issues in the review and publication of research with potential dual-use implications. More work is needed to establish consensus on standards for the review and publication of dual-use research of concern in life science journals. PMID:22871221

  1. Isotopes and Trace Elements as Natal Origin Markers of Helicoverpa armigera – An Experimental Model for Biosecurity Pests

    PubMed Central

    Holder, Peter W.; Armstrong, Karen; Van Hale, Robert; Millet, Marc-Alban; Frew, Russell; Clough, Timothy J.; Baker, Joel A.

    2014-01-01

    Protecting a nation's primary production sector and natural estate is heavily dependent on the ability to determine the risk presented by incursions of exotic insect species. Identifying the geographic origin of such biosecurity breaches can be crucial in determining this risk and directing the appropriate operational responses and eradication campaigns, as well as ascertaining incursion pathways. Reading natural abundance biogeochemical markers using mass spectrometry is a powerful tool for tracing ecological pathways as well as provenance determination of commercial products and items of forensic interest. However, application of these methods to trace insects has been underutilised to date and our understanding in this field is still in a phase of basic development. In addition, biogeochemical markers have never been considered in the atypical situation of a biosecurity incursion, where sample sizes are often small, and of unknown geographic origin and plant host. These constraints effectively confound the interpretation of the one or two isotope geo-location markers systems that are currently used, which are therefore unlikely to achieve the level of provenance resolution required in biosecurity interceptions. Here, a novel approach is taken to evaluate the potential for provenance resolution of insect samples through multiple biogeochemical markers. The international pest, Helicoverpa armigera, has been used as a model species to assess the validity of using naturally occurring δ2H, 87Sr/86Sr, 207Pb/206Pb and 208Pb/206Pb isotope ratios and trace element concentration signatures from single moth specimens for regional assignment to natal origin. None of the biogeochemical markers selected were individually able to separate moths from the different experimental regions (150–3000 km apart). Conversely, using multivariate analysis, the region of origin was correctly identified for approximately 75% of individual H. armigera samples. The geographic resolution

  2. Criminal genomic pragmatism: prisoners' representations of DNA technology and biosecurity.

    PubMed

    Machado, Helena; Silva, Susana

    2012-01-01

    Within the context of the use of DNA technology in crime investigation, biosecurity is perceived by different stakeholders according to their particular rationalities and interests. Very little is known about prisoners' perceptions and assessments of the uses of DNA technology in solving crime. To propose a conceptual model that serves to analyse and interpret prisoners' representations of DNA technology and biosecurity. A qualitative study using an interpretative approach based on 31 semi-structured tape-recorded interviews was carried out between May and September 2009, involving male inmates in three prisons located in the north of Portugal. The content analysis focused on the following topics: the meanings attributed to DNA and assessments of the risks and benefits of the uses of DNA technology and databasing in forensic applications. DNA was described as a record of identity, an exceptional material, and a powerful biometric identifier. The interviewees believed that DNA can be planted to incriminate suspects. Convicted offenders argued for the need to extend the criteria for the inclusion of DNA profiles in forensic databases and to restrict the removal of profiles. The conceptual model entitled criminal genomic pragmatism allows for an understanding of the views of prison inmates regarding DNA technology and biosecurity.

  3. Biosecurity policies at international life science journals.

    PubMed

    van Aken, Jan; Hunger, Iris

    2009-03-01

    The prospect of bioterrorism has raised concerns about the potential abuse of scientific information for malign purposes and the pressure on scientific publishers to prevent the publication of "recipes" for weapons of mass destruction. Here we present the results of a survey of 28 major life science journals--20 English-language international journals and 3 Chinese and 5 Russian journals--with regard to their biosecurity policies and procedures. The survey addressed the extent to which life science journals have implemented biosecurity procedures in recent years, how authors and reviewers are advised about these procedures and the underlying concerns, and what the practical experiences have been. Few of the English-language publishers and none of the Russian and Chinese publishers surveyed implement formal biosecurity policies or inform their authors and reviewers about potentially sensitive issues in this area.

  4. Biosecurity-Based Interventions and Strategies To Reduce Campylobacter spp. on Poultry Farms▿

    PubMed Central

    Newell, D. G.; Elvers, K. T.; Dopfer, D.; Hansson, I.; Jones, P.; James, S.; Gittins, J.; Stern, N. J.; Davies, R.; Connerton, I.; Pearson, D.; Salvat, G.; Allen, V. M.

    2011-01-01

    The prevention and control of Campylobacter colonization of poultry flocks are important public health strategies for the control of human campylobacteriosis. A critical review of the literature on interventions to control Campylobacter in poultry on farms was undertaken using a systematic approach. Although the focus of the review was on aspects appropriate to the United Kingdom poultry industry, the research reviewed was gathered from worldwide literature. Multiple electronic databases were employed to search the literature, in any language, from 1980 to September 2008. A primary set of 4,316 references was identified and scanned, using specific agreed-upon criteria, to select relevant references related to biosecurity-based interventions. The final library comprised 173 references. Identification of the sources of Campylobacter in poultry flocks was required to inform the development of targeted interventions to disrupt transmission routes. The approach used generally involved risk factor-based surveys related to culture-positive or -negative flocks, usually combined with a structured questionnaire. In addition, some studies, either in combination or independently, undertook intervention trials. Many of these studies were compromised by poor design, sampling, and statistical analysis. The evidence for each potential source and route of transmission on the poultry farm was reviewed critically, and the options for intervention were considered. The review concluded that, in most instances, biosecurity on conventional broiler farms can be enhanced and this should contribute to the reduction of flock colonization. However, complementary, non-biosecurity-based approaches will also be required in the future to maximize the reduction of Campylobacter-positive flocks at the farm level. PMID:21984249

  5. [Nursing students' point of view on biosecurity and patient safety].

    PubMed

    Cararro, Telma Elisa; Gelbcke, Francine Lima; Sebold, Luciara Fabiane; Kempfer, Silvana Silveira; Zapelini, Maria Christina; Waterkemper, Roberta

    2012-09-01

    This study is aimed at identifying the knowledge of nursing students about the subject area of patient safety and its relationship with the teaching of biosecurity. Exploratory qualitative study conducted at the Universidade Federal de Santa Catarina (Federal University of Santa Catarina), with 17 students in the third phase of the Undergraduate Nursing Program. Three categories emerged after an exhaustive reading of the responses caring for self and others; biosecurity and care for the environment; biosecurity: health education and continuing education in health services. The following issues were identified, students' concern about risk prevention, care and self care as prerogatives for patient's safety; and education as a proposal for the minimization of risks. The study of biosecurity is considered important in undergraduate studies, minimizing losses and mistakes in the undergraduate students' conduct.

  6. Improving Smallholder Farmer Biosecurity in the Mekong Region Through Change Management.

    PubMed

    Young, J R; Evans-Kocinski, S; Bush, R D; Windsor, P A

    2015-10-01

    Transboundary animal diseases including foot-and-mouth disease and haemorrhagic septicaemia remain a major constraint for improving smallholder large ruminant productivity in the Mekong region, producing negative impacts on rural livelihoods and compromising efforts to reduce poverty and food insecurity. The traditional husbandry practices of smallholders largely exclude preventive health measures, increasing risks of disease transmission. Although significant efforts have been made to understand the social aspects of change development in agricultural production, attention to improving the adoption of biosecurity has been limited. This study reviews smallholder biosecurity risk factors identified in the peer-reviewed literature and from field research observations conducted in Cambodia and Laos during 2006-2013, considering these in the context of a change management perspective aimed at improving adoption of biosecurity measures. Motivation for change, resistance to change, knowledge management, cultural dimensions, systems theory and leadership are discussed. Due to geographical, physical and resource variability, the implementation of biosecurity interventions suitable for smallholders is not a 'one size fits all'. Smallholders should be educated in biosecurity principles and empowered to make personal decisions rather than adopt prescribed pre-defined interventions. Biosecurity interventions should be aligned with smallholder farmer motivations, preferably offering clear short-term risk management benefits that elicit interest from smallholders. Linking biosecurity and disease control with improved livestock productivity provides opportunities for sustainable improvements in livelihoods. Participatory research and extension that improves farmer knowledge and practices offers a pathway to elicit sustainable broad-scale social change. However, examples of successes need to be communicated both at the 'evidence-based level' to influence regional policy

  7. Natural or deliberate outbreak in Pakistan: how to prevent or detect and trace its origin: biosecurity, surveillance, forensics.

    PubMed

    Shinwari, Zabta Khan; Khalil, Ali Talha; Nasim, Anwar

    2014-08-01

    Over the last few decades biosecurity and biosafety have emerged as a prominent public health concern due to some high-profile accidents. Effective strategies to deal with the outbreak, whether deliberate or non-deliberate requires a multidisciplinary approach and coordinated decision-making by various state departments such as health, forensics, agriculture, environment, intelligence, law and enforcement, etc. In a dynamic global environment and the overwhelming asymmetric threats from the non-state actors, it is of utmost importance to understand the biosecurity issues and initiate a coordinated global effort to cope with biosecurity and biosafety breaches and develop an as effective response mechanism. An attractive choice for the terrorists, state enemies and non-state actors is the use of biological weapons. An unwanted incident may not only bring chaos to the people, but also can inflict severe economic damage industrially and locally as was in the notorious foot-and-mouth disease outbreak. Because of special geopolitical compulsion, Pakistan is one of the hot spots where special action needs to be taken. The current review focuses on the various approaches, technologies that can be used to alleviate the chances of biosafety and biosecurity incident and emphasizes the role of modern technology that can be used in this regard.

  8. Biosecurity through Public Health System Design.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beyeler, Walter E.; Finley, Patrick D.; Arndt, William

    We applied modeling and simulation to examine the real-world tradeoffs between developingcountry public-health improvement and the need to improve the identification, tracking, and security of agents with bio-weapons potential. Traditionally, the international community has applied facility-focused strategies for improving biosecurity and biosafety. This work examines how system-level assessments and improvements can foster biosecurity and biosafety. We modeled medical laboratory resources and capabilities to identify scenarios where biosurveillance goals are transparently aligned with public health needs, and resource are distributed in a way that maximizes their ability to serve patients while minimizing security a nd safety risks. Our modeling platform simulatesmore » key processes involved in healthcare system operation, such as sample collection, transport, and analysis at medical laboratories. The research reported here extends the prior art by provided two key compone nts for comparative performance assessment: a model of patient interaction dynamics, and the capability to perform uncertainty quantification. In addition, we have outlined a process for incorporating quantitative biosecurity and biosafety risk measures. Two test problems were used to exercise these research products examine (a) Systemic effects of technological innovation and (b) Right -sizing of laboratory networks.« less

  9. On-farm biosecurity practices and causes of preweaning mortality in Canadian commercial mink kits.

    PubMed

    Compo, Nicole; Pearl, David L; Tapscott, Brian; Storer, Amanda; Hammermueller, Jutta; Brash, Marina; Turner, Patricia V

    2017-09-08

    Mink are an important animal commodity group in Canada and excessive kit mortality represents a significant loss to production. National biosecurity standards have been developed for Canadian mink farms, but it is unclear how well these standards have been implemented as there are no studies correlating management practices of mink producers with causes of death in mink kits. To that end, we surveyed Ontario mink producers on their biosecurity and management practices and conducted almost 5660 post mortem examinations on found-dead, preweaned kits to characterize mink farm biosecurity practices and causes of death in preweaned kits. We found that very few biosecurity and management practices were uniformly used by producers, despite good awareness of appropriate practices. Use of personal protective equipment was implemented by fewer than 50% of respondents, while control of mink shed access, disinfection of feed containers after use, and use of a rodent control program were the only practices implemented by greater than 70% of respondents. Only 18% of producers reported regular use of antimicrobials in feed or water, although 91% stated they used antimicrobials for treatment of bacterial diseases on a regular basis. On post mortem examination, no gross abnormalities were noted in 71% of the kits, 45% were thought to be stillborn or aborted, 27% had some form of abnormal fluid distribution in the body, and 2% had a congenital malformation. A subset of 69 gastrointestinal tract samples was submitted for bacterial culture, of which 45 samples yielded sufficient growth. Most interesting was the identification of Salmonella enterica serovar Heidelberg in 11% of samples. The results of this study will provide a benchmark for Canadian mink producers and their veterinarians, defining the areas to which greater attention should be given to ensure more rigorous biosecurity practices are in place. Ultimately, these improvements in practices may contribute to increased mink

  10. 'Getting the biosecurity architecture right' in the Asia-Pacific region.

    PubMed

    Minehata, Masamichi

    2012-01-01

    This paper offers insights to enhance biosecurity in the Asia-Pacific by asking three questions. What risks/threats are significant in the region? Which security measures should be prioritized? What kind of regional--institutionalized and ad-hoc--arrangements should be implemented? By doing so the paper specifically focuses on two important aspects of biosecurity. Firstly, the issue of immediate capacity-building in the context of disaster relief, public health preparedness and biodefence. Secondly, the long-term preventive aspect, namely education and awareness-raising activities to more broadly promote responsible conduct in life science research in terms of laboratory accidents as well as the intentional use of biological agents for hostile purposes. In order to promote both aspects of biosecurity within the policy process, the paper analyses the strategic value of the US-Japan partnership in its efforts to build a biosecurity architecture in the Asia-Pacific region.

  11. Biosecurity interceptions of an invasive lizard: origin of stowaways and human-assisted spread within New Zealand

    PubMed Central

    Chapple, David G; Whitaker, Anthony H; Chapple, Stephanie N J; Miller, Kimberly A; Thompson, Michael B

    2013-01-01

    Globalization, and the resultant movement of animals beyond their native range, creates challenges for biosecurity agencies. Limited records of unintentional introductions inhibit our understanding of the trade pathways, transport vectors and mechanisms through which hitchhiker organisms are spread as stowaways. Here, we adopt a phylogeographic approach to determine the source and human-mediated dispersal pathways of New Zealand's only invasive lizard, the delicate skink (Lampropholis delicata), intercepted by biosecurity agencies in New Zealand. Biosecurity agencies correctly predicted the source region of 77% of stowaways, which were usually solitary adults, arriving via air or sea pathways during the cooler months, evading initial border checks and alive when detected. New arrivals from Australia comprised 16% of detections originating from the region between Brisbane and Sydney. Our analyses indicate human-mediated dispersal has driven the post-border spread of L. delicata within New Zealand. Propagule pressure was substantially greater for L. delicata compared with the noninvasive, congeneric Lampropholis guichenoti. Our results highlight the transport pathways, spread mechanisms, and stowaway characteristics of Lampropholis lizards entering New Zealand, which could enhance current biosecurity protocols and prevent the establishment of additional lizard species. PMID:23467589

  12. Biosafety and biosecurity measures: management of biosafety level 3 facilities.

    PubMed

    Zaki, Adel N

    2010-11-01

    With the increasing biological threat from emerging infectious diseases and bioterrorism, it has become essential for governments around the globe to increase awareness and preparedness for identifying and containing those agents. This article introduces the basic concepts of laboratory management, laboratory biosafety and laboratory biosecurity. Assessment criteria for laboratories' biorisk should include both biosafety and biosecurity measures. The assessment requires setting specific goals and selecting management approaches. In order to implement technologies at the laboratory working level, a management team should be created whose role is to implement biorisk policies, rules and regulations appropriate for that facility. Rules and regulations required by government authorities are presented, with special emphasis on methods for air control, and liquid and solid waste management. Management and biorisk measures and appropriate physical facilities must keep pace, ensuring efficient facilities that protect workers, the environment, the product (research, diagnostic and/or vaccine) and the biological pathogen. Published by Elsevier B.V.

  13. Social representations of biosecurity in nursing: occupational health and preventive care.

    PubMed

    Sousa, Álvaro Francisco Lopes de; Queiroz, Artur Acelino Francisco Luz Nunes; Oliveira, Layze Braz de; Moura, Maria Eliete Batista; Batista, Odinéa Maria Amorim; Andrade, Denise de

    2016-01-01

    to understand the biosecurity social representations by primary care nursing professionals and analyze how they articulate with quality of care. exploratory and qualitative research based on social representation theory. The study participants were 36 nursing workers from primary health care in a state capital in the Northeast region of Brazil. The data were analyzed by descending hierarchical classification. five classes were obtained: occupational accidents suffered by professionals; occupational exposure to biological agents; biosecurity management in primary health care; the importance of personal protective equipment; and infection control and biosecurity. the different positions taken by the professionals seem to be based on a field of social representations related to the concept of biosecurity, namely exposure to accidents and risks to which they are exposed. However, occupational accidents are reported as inherent to the practice.

  14. Determinants of biosecurity behaviour of British cattle and sheep farmers-a behavioural economics analysis.

    PubMed

    Toma, Luiza; Stott, Alistair W; Heffernan, Claire; Ringrose, Siân; Gunn, George J

    2013-03-01

    The paper analyses the impact of a priori determinants of biosecurity behaviour of farmers in Great Britain. We use a dataset collected through a stratified telephone survey of 900 cattle and sheep farmers in Great Britain (400 in England and a further 250 in Wales and Scotland respectively) which took place between 25 March 2010 and 18 June 2010. The survey was stratified by farm type, farm size and region. To test the influence of a priori determinants on biosecurity behaviour we used a behavioural economics method, structural equation modelling (SEM) with observed and latent variables. SEM is a statistical technique for testing and estimating causal relationships amongst variables, some of which may be latent using a combination of statistical data and qualitative causal assumptions. Thirteen latent variables were identified and extracted, expressing the behaviour and the underlying determining factors. The variables were: experience, economic factors, organic certification of farm, membership in a cattle/sheep health scheme, perceived usefulness of biosecurity information sources, knowledge about biosecurity measures, perceived importance of specific biosecurity strategies, perceived effect (on farm business in the past five years) of welfare/health regulation, perceived effect of severe outbreaks of animal diseases, attitudes towards livestock biosecurity, attitudes towards animal welfare, influence on decision to apply biosecurity measures and biosecurity behaviour. The SEM model applied on the Great Britain sample has an adequate fit according to the measures of absolute, incremental and parsimonious fit. The results suggest that farmers' perceived importance of specific biosecurity strategies, organic certification of farm, knowledge about biosecurity measures, attitudes towards animal welfare, perceived usefulness of biosecurity information sources, perceived effect on business during the past five years of severe outbreaks of animal diseases, membership

  15. Biosecurity Management of Submarine Niche Areas: the Effect of Water Pressure on Biofouling Survival

    DTIC Science & Technology

    2014-01-01

    UNCLASSIFIED UNCLASSIFIED Biosecurity Management of Submarine Niche Areas: the Effect of Water Pressure on Biofouling Survival Clare...operational impacts and biosecurity risks. Approved for public release RELEASE LIMITATION UNCLASSIFIED...UNCLASSIFIED UNCLASSIFIED Biosecurity Management of Submarine Niche Areas: the Effect of Water Pressure on Biofouling Survival Executive Summary

  16. Associations between biosecurity practices and bovine digital dermatitis in Danish dairy herds.

    PubMed

    Oliveira, Victor H S; Sørensen, Jan T; Thomsen, Peter T

    2017-10-01

    The relationship between biosecurity and digital dermatitis (DD) was evaluated in 8,269 cows from a convenience sample of 39 freestall dairy herds. The hypothesis was that poor implementation of biosecurity was associated with higher within-herd prevalence of DD. All lactating cows were scored as negative or positive for DD at the hind legs during milking in the milking parlor. Information about biosecurity was obtained through questionnaires addressed to farmers, on-farm observations, and information from the Danish Cattle Database (www.seges.dk). These assessment tools covered potential infection sources of DD pathogens to susceptible cows (e.g., via animals, humans, manure, vehicles, equipment, and facilities). External and internal biosecurity measures were explanatory variables in 2 separate logistic regression models, whereas within-herd DD prevalence was the outcome. Overall DD prevalence among cows and herds were 24 and 97%, respectively; the within-herd DD prevalence ranged from 0 to 56%. Poor external biosecurity measures associated with higher prevalence of DD were recent animal purchase, access to pasture, lack of boots available for visitors, farm staff working at other dairy farms as well, hoof trimming without a professional attending, and animal transporters having access to cattle area. For internal biosecurity, higher DD prevalence were associated with infrequent hoof bathing, manure scraping less than 8 times a day, manure removal direction from cows to heifers, animal pens' exit without water hoses, manure-handling vehicle used in other activities, and water troughs contaminated with manure. These findings showed that improvements on biosecurity may be beneficial for controlling DD in dairy herds. The study is relevant for farmers facing problems with DD, as well as hoof trimmers, advisors, and veterinarians, who can use the results for optimized recommendations regarding biosecurity in relation to DD. Furthermore, our results might be

  17. Biosecurity practices and causes of enteritis on Ontario meat rabbit farms

    PubMed Central

    Kylie, Jennifer; Brash, Marina; Whiteman, Ashley; Tapscott, Brian; Slavic, Durda; Weese, J. Scott; Turner, Patricia V.

    2017-01-01

    Infectious enterocolitis is a significant cause of mortality in meat rabbits. Disease risk is enhanced by intensive rearing practices and poor on-farm biosecurity. This investigation was undertaken in farmed meat rabbits during an Ontario-wide outbreak of enteritis with high mortality to determine the prevalence of causative agents. A survey evaluating on-farm biosecurity practices was also conducted to identify potential means of pathogen contamination and zoonotic risks. Gross and microscopic pathology evaluations combined with microbiologic testing were conducted on 95 rabbits over spring and winter months. Escherichia coli and Clostridium spiroforme were most commonly associated with enteritis in rabbits regardless of age or season and lesions were significantly more severe in mature does (P < 0.0001). The survey results demonstrated a lack of consistent on-farm biosecurity practices. The infectious nature of enteric disease of rabbits combined with poor biosecurity practices may contribute to disease transmission within and between farms. PMID:28588327

  18. Biosecurity practices and causes of enteritis on Ontario meat rabbit farms.

    PubMed

    Kylie, Jennifer; Brash, Marina; Whiteman, Ashley; Tapscott, Brian; Slavic, Durda; Weese, J Scott; Turner, Patricia V

    2017-06-01

    Infectious enterocolitis is a significant cause of mortality in meat rabbits. Disease risk is enhanced by intensive rearing practices and poor on-farm biosecurity. This investigation was undertaken in farmed meat rabbits during an Ontario-wide outbreak of enteritis with high mortality to determine the prevalence of causative agents. A survey evaluating on-farm biosecurity practices was also conducted to identify potential means of pathogen contamination and zoonotic risks. Gross and microscopic pathology evaluations combined with microbiologic testing were conducted on 95 rabbits over spring and winter months. Escherichia coli and Clostridium spiroforme were most commonly associated with enteritis in rabbits regardless of age or season and lesions were significantly more severe in mature does ( P < 0.0001). The survey results demonstrated a lack of consistent on-farm biosecurity practices. The infectious nature of enteric disease of rabbits combined with poor biosecurity practices may contribute to disease transmission within and between farms.

  19. Towards a global barcode library for Lymantria (Lepidoptera: Lymantriinae) tussock moths of biosecurity concern

    Treesearch

    Jeremy R. deWaard; Andrew Mitchell; Melody A. Keena; David Gopurenko; Laura M. Boykin; Karen F. Armstrong; Michael G. Pogue; Joao Lima; Robin Floyd; Robert H. Hanner; Leland M. Humble

    2010-01-01

    This study demonstrates the efficacy of DNA barcodes for diagnosing species of Lymantria and reinforces the view that the approach is an under-utilized resource with substantial potential for biosecurity and surveillance. Biomonitoring agencies currently employing the NB restriction digest system would gather more information by transitioning to the...

  20. Economic aspects of agricultural and food biosecurity.

    PubMed

    Hennessy, David A

    2008-03-01

    Concerns about biosecurity in the food system raise a variety of issues about how the system is presently organized, why it might be vulnerable, what we could reasonably do to better secure it, and the costs of doing so. Emphasizing the role of incentives in efficient resource allocation, this article considers economic dimensions of three aspects of the general problem. One is the global problem, or the way biosecurity measures can affect how countries relate to each other and the global consequences that result. Another is how to best manage the immediate aftermath of a realized threat in order to minimize damage. The third is how to seek to prevent realization of the threat. Some policy alternatives are presented.

  1. Veterinary Students' Knowledge and Perceptions About Antimicrobial Stewardship and Biosecurity-A National Survey.

    PubMed

    Hardefeldt, Laura; Nielsen, Torben; Crabb, Helen; Gilkerson, James; Squires, Richard; Heller, Jane; Sharp, Claire; Cobbold, Rowland; Norris, Jacqueline; Browning, Glenn

    2018-04-18

    A better understanding of veterinary students’ perceptions, attitudes, and knowledge about antimicrobial stewardship and biosecurity could facilitate more effective education of future veterinarians about these important issues. A multicenter cross-sectional study was performed by administering a questionnaire to veterinary students expected to graduate in 2017 or 2018 in all Australian veterinary schools. Four hundred and seventy-six of 1246 students (38%) completed the survey. Many students were unaware of the high importance of some veterinary drugs to human medicine, specifically enrofloxacin and cefovecin (59% and 47% of responses, respectively). Fewer than 10% of students would use appropriate personal protective equipment in scenarios suggestive of Q fever or psittacosis. Students expected to graduate in 2018 were more likely to select culture and susceptibility testing in companion animal cases (OR 1.89, 95% CI 1.33–2.69, p < 0.001), and were more likely to appropriately avoid antimicrobials in large animal cases (OR 1.75, 95% CI 1.26–2.44, p = 0.001) than those expected to graduate in 2017. However, 2018 graduates were less likely to correctly identify the importance rating of veterinary antimicrobials for human health (OR 0.48, 95% CI 0.34–0.67, p < 0.001) than 2017 graduates. Students reported having a good knowledge of antimicrobial resistance, and combating resistance, but only 34% thought pharmacology teaching was adequate and only 20% said that teaching in lectures matched clinical teaching. Efforts need to be made to harmonize preclinical and clinical teaching, and greater emphasis is needed on appropriate biosecurity and antimicrobial stewardship.

  2. Biosecurity Conditions in Small Commercial Chicken Farms, Bangladesh 2011-2012.

    PubMed

    Rimi, N A; Sultana, R; Muhsina, M; Uddin, B; Haider, N; Nahar, N; Zeidner, N; Sturm-Ramirez, K; Luby, S P

    2017-06-01

    In Bangladesh, highly pathogenic avian influenza H5N1 is endemic in poultry. This study aimed to understand the biosecurity conditions and farmers' perception of avian influenza biosecurity in Bangladeshi small commercial chicken farms. During 2011-2012, we conducted observations, in-depth interviews and group discussions with poultry farmers in 16 farms and in-depth interviews with seven local feed vendors from two districts. None of the farms were completely segregated from people, backyard poultry, other animals, households, other poultry farms or large trees. Wild birds and rodents accessed the farms for poultry feed. Farmers usually did not allow the buyers to bring egg trays inside their sheds. Spraying disinfectant in the shed and removing feces were the only regular cleaning and disinfection activities observed. All farmers sold or used untreated feces as fish feed or fertilizer. Farmers were more concerned about Newcastle disease and infectious bursal disease than about avian influenza. Farmers' understanding about biosecurity and avian influenza was influenced by local vendors. While we seldom observed flock segregation, some farmers used measures that involved additional cost or effort to protect their flocks. These farmers could be motivated by interventions to protect their investment from diseases they consider harmful. Future interventions could explore the feasibility and effectiveness of low-cost alternative biosecurity measures.

  3. Biosecurity procedures for the environmental management of carcasses burial sites in Korea.

    PubMed

    Kim, Geon-Ha; Pramanik, Sudipta

    2016-12-01

    Avian influenza and foot-and-mouth disease are two main contagious pathogenic viral disease which are responsible for the massive burials of livestock in Korea since burial is the primary measure to control these outbreaks. Biosecurity is a set of preventive measures designed to prevent the risk of spreading of these infectious diseases. The main objective of this paper is to discuss about the requirements of biosecurity and develop protocol outlines for environmental management of burial sites in Korea. Current practice prescribes to minimize the potential for on-farm pollution and the spread of the infectious diseases. Specific biosecurity procedures such as proper assessment of leachate quality, safe handling and disposal of leachate, adequate leachate pollution monitoring, necessary seasonal management of burial site, and appropriate sterilization process must be carried out to prevent the indirect transmission of pathogens from the burial sites. Policy makers should acquire robust knowledge of biosecurity for establishing more effective future legislation for carcasses disposal in Korea.

  4. Microorganisms: Good or Evil, MIRRI Provides Biosecurity Awareness.

    PubMed

    Smith, David; Martin, Dunja; Novossiolova, Tatyana

    2017-03-01

    The life-science community is a key stakeholder in the effort to ensure that the advances in biotechnology are not misused. Unfortunately, to date, the engagement of life scientists with issues of biosecurity has been limited. Microorganisms have been harnessed for the benefit of humankind but in the wrong hands could be used in direct or indirect acts against humans, livestock, crops, food, water infrastructure and other economically valuable entities. The Microbial Resources Research Infrastructure in its preparatory phase has addressed the topic implementing a code of conduct as part of its programme of prevention of malicious use and continues to work with the international community to raise awareness of best practice to avoid misuse of microorganisms. Biosecurity has become a major concern for several countries creating numerous activities to put in place counter measures, risk assessment, legislation and emergency response. The goal is to implement measures to protect us against malicious use of microorganisms, their products, information and technology transfer. Through this paper, we wish to discuss some of the activities that are underway, mention key educational tools and provide scientists with information on addressing biosecurity issues.

  5. Biocontainment, biosecurity, and security practices in beef feedyards.

    PubMed

    Brandt, Aric W; Sanderson, Michael W; DeGroot, Brad D; Thomson, Dan U; Hollis, Larry C

    2008-01-15

    To determine the biocontainment, biosecurity, and security practices at beef feedyards in the Central Plains of the United States. Survey. Managers of feedyards in Colorado, Kansas, Nebraska, Oklahoma, and Texas that feed beef cattle for finish before slaughter; feedyards had to have an active concentrated animal feeding operation permit with a 1-time capacity of >or= 1,000 cattle. A voluntary survey of feedyard personnel was conducted. Identified feedyard personnel were interviewed and responses regarding facility design, security, employees, disease preparedness, feedstuffs, hospital or treatment systems, sanitation, cattle sources, handling of sick cattle, and disposal of carcasses were collected in a database questionnaire. The survey was conducted for 106 feedyards with a 1-time capacity that ranged from 1,300 to 125,000 cattle. Feedyards in general did not have high implementation of biocontainment, biosecurity, or security practices. Smaller feedyards were, in general, less likely to use good practices than were larger feedyards. Results of the survey provided standard practices for biocontainment, biosecurity, and security in feedyards located in Central Plains states. Information gained from the survey results can be used by consulting veterinarians and feedyard managers as a basis for discussion and to target training efforts.

  6. Report of the Working Group on Strengthening the Biosecurity of the United States

    DTIC Science & Technology

    2009-10-01

    affecting humans and granted the USDA authority comparable to that of the CDC to regulate entities that possess, use, and transfer BSAT that present a... fruitful history in academia, and includes research on pathogens that only recently have been designated “select agents and toxins.” This open...risk, with less emphasis on biosecurity and biodefense, and fail to consider issues that affect U.S. national security (e.g., selection of an agent

  7. Creating a framework for the prioritization of biosecurity risks to the New Zealand dairy industry.

    PubMed

    Muellner, P; Hodges, D; Ahlstrom, C; Newman, M; Davidson, R; Pfeiffer, D; Marshall, J; Morley, C

    2018-03-25

    The New Zealand dairy sector relies on robust biosecurity measures to control and mitigate a wide range of threats to the industry. To optimize the prioritization of organisms and manage the risk they pose to the sector in a transparent and credible way, the Dairy Biosecurity Risk Evaluation Framework (D-BRiEF) was developed. This comprehensive framework was specifically designed for decision support, using a standardized approach to address the full spectrum of biosecurity threats to the sector, including exotic and endemic animal disease organisms, pest plants and insects. D-BRiEF is underpinned by three main processes, namely (i) hazard identification; (ii) multicriteria risk assessment; and (iii) communication for risk management. Expert knowledge and empirical data, including associated uncertainty, are harnessed in a standardized format. Results feed into a probability-impact model that was developed in close collaboration with dairy sector economists to provide overall comparative 10-year quantitative economic impact estimates for each assessed risk organism. A description of the overarching framework, which applies to diverse organism groups, is presented with detailed methodology on both endemic and exotic animal disease risk organisms. Examples of visual outputs are included, although actual ranking results are not reported due to industry confidentiality. D-BRiEF can provide a decision advantage to DairyNZ biosecurity risk managers and sector stakeholders by creating a transparent process that can be interrogated and updated at multiple levels to fully understand the layers of risk posed by different organisms. © 2018 Blackwell Verlag GmbH.

  8. Enhancing knowledge and awareness of biosecurity practices for control of African swine fever among smallholder pig farmers in four districts along the Kenya-Uganda border.

    PubMed

    Nantima, Noelina; Davies, Jocelyn; Dione, Michel; Ocaido, Michael; Okoth, Edward; Mugisha, Anthony; Bishop, Richard

    2016-04-01

    A study was undertaken along the Kenya-Uganda border in four districts of Tororo and Busia (Uganda) and Busia and Teso (Kenya) to understand smallholder farmers' knowledge, practices and awareness of biosecurity measures. Information was collected by administering questionnaires to 645 randomly selected pig households in the study area. In addition, focus group discussions were carried out in 12 villages involving 248 people using a standardized list of questions. The outcome suggested that there was a very low level of awareness of biosecurity practices amongst smallholder farmers. We conclude that adoption of specific biosecurity practices by smallholder farmers is feasible but requires institutional support. There is a clear requirement for government authorities to sensitize farmers using approaches that allow active participation of farmers in the design, planning and implementation of biosecurity practices to enable enhanced adoption.

  9. Biosecurity Plan for Palmyra Atoll

    USGS Publications Warehouse

    Hathaway, Stacie A.; Fisher, Robert N.

    2010-01-01

    This Biosecurity Plan for Palmyra Atoll was developed for The Nature Conservancy (TNC) Palmyra Program to refine and expand goals and objectives developed through the Conservation Action Plan process. The Biosecurity Plan is one in a series of adaptive management plans designed to achieve TNC's mission toward the protection and enhancement of native wildlife and habitat. The Biosecurity Plan focuses on ecosystem security, and specifically identifies and addresses issues related to non-native and potentially invasive species. The Plan attempts to identify pathways of invasion and strategies for preventing or reducing new introductions. Overall, the Biosecurity Plan provides a framework to implement and track the progress of conservation and restoration goals related to non-native species on Palmyra Atoll. Palmyra Atoll is one of the Northern Line Islands in the Pacific Ocean southwest of the Hawai`ian Islands. It consists of many heavily vegetated islets arranged in a horseshoe pattern around four lagoons and surrounded by a coral reef. At present, Palmyra Atoll harbors various non-native or invasive species in the terrestrial and marine ecosystems. The most notable examples of terrestrial invasive species include coconut trees (Cocos nucifera) and black rats (Rattus rattus). Although it is unclear whether they are non-native, coconut trees are currently the most dominant plant across Palmyra Atoll. They compete with native plant species for space and resources, and are potentially detrimental to seabirds dependent on native vegetation. Black rats are known to predate ground-nesting seabirds and are likely responsible for the lack of burrowing seabird reproduction on Palmyra Atoll. The most notable example of a marine invasive species is the corallimorph (Rhodactis howsei). Although Rhodactis howsei is a native species, it can take advantage of human-altered habitat and significantly change the natural habitat by aggressively outcompeting native corals. Although the

  10. An ecohealth assessment of poultry production clusters (PPCs) for the livelihood and biosecurity improvement of small poultry producers in Asia.

    PubMed

    Wang, Libin; Basuno, Edi; Nguyen, Tuan; Aengwanich, Worapol; Ilham, Nyak; Li, Xiaoyun

    2015-01-01

    Poultry production cluster (PPC) programs are key strategies in many Asian countries to engage small commercial poultry producers in high-value production chains and to control infectious poultry diseases. This study assessed the multiple impacts of PPCs through a transdisciplinary ecohealth approach in four Asian countries, and drew the implications for small producers to improve their livelihoods and reduce the risk of spreading infectious diseases in the poultry sector. The data collection combined both quantitative and qualitative methods. It comprised: formal structured household survey questionnaires, measuring the biosecurity level of poultry farms with a biosecurity score card; and key informant interviews. Descriptive statistics were used to process the quantitative data and a content analysis was used to process the qualitative data. This research found that poultry farms in clusters do not necessarily have better economic performance than those outside PPCs. Many farmers in PPCs only consider them to be an advantage for expanding the scale of their poultry operations and improving household incomes, and they are less concerned about-and have limited capacities to-enhancing biosecurity and environmental management. We measured the biosecurity level of farms in PPCs through a 14-item checklist and found that biosecurity is generally very low across all sample sites. The increased flies, mosquitoes, rats, and smells in and around PPCs not only pollute the environment, but also cause social conflicts with the surrounding communities. This research concluded that a poultry cluster, mainly driven by economic objectives, is not necessarily a superior model for the control of infectious diseases. The level of biosecurity in PPCs was found to be low. Given the intensity of poultry operations in PPCs (farms are densely packed into clusters), and the close proximity to residential areas of some PPCs, the risk of spreading infectious diseases, in fact, increases

  11. The changing world of biocontainment and biosecurity.

    PubMed

    Jeggo, M

    2007-01-01

    Since the 1980s, a number of key events have significantly altered our ideas on biosecurity and the role of biocontainment laboratories, such as the bovine spongiform encephalopathy (BSE) and severe acute respiratory syndrome (SARS) outbreaks and the anthrax episode of 2001 in the USA. This has resulted in the development of plans to build "high containment" facilities around the world and an array of new regulations at both national and international levels regarding the management of pathogens, the operation of high containment facilities, the use of genetically modified material, and the transportation of such agents and personnel security issues. Considering the cost, however, it is debatable whether every country needs to build its own high containment facility. The Australian Animal Health Laboratory (AAHL) provides an example of what might be considered best practice in biocontainment while considering regulations, cost and need.

  12. Biosecurity Implications of New Technology and Discovery in Plant Virus Research

    PubMed Central

    MacDiarmid, Robin; Rodoni, Brendan; Melcher, Ulrich; Ochoa-Corona, Francisco; Roossinck, Marilyn

    2013-01-01

    Human activity is causing new encounters between viruses and plants. Anthropogenic interventions include changing land use, decreasing biodiversity, trade, the introduction of new plant and vector species to native landscapes, and changing atmospheric and climatic conditions. The discovery of thousands of new viruses, especially those associated with healthy-appearing native plants, is shifting the paradigm for their role within the ecosystem from foe to friend. The cost of new plant virus incursions can be high and result in the loss of trade and/or production for short or extended periods. We present and justify three recommendations for plant biosecurity to improve communication about plant viruses, assist with the identification of viruses and their impacts, and protect the high economic, social, environmental, and cultural value of our respective nations' unique flora: 1) As part of the burden of proof, countries and jurisdictions should identify what pests already exist in, and which pests pose a risk to, their native flora; 2) Plant virus sequences not associated with a recognized virus infection are designated as “uncultured virus” and tentatively named using the host plant species of greatest known prevalence, the word “virus,” a general location identifier, and a serial number; and 3) Invest in basic research to determine the ecology of known and new viruses with existing and potential new plant hosts and vectors and develop host-virus pathogenicity prediction tools. These recommendations have implications for researchers, risk analysts, biosecurity authorities, and policy makers at both a national and an international level. PMID:23950706

  13. Marburg biosafety and biosecurity scale (MBBS): a framework for risk assessment and risk communication.

    PubMed

    Dickmann, Petra; Apfel, Franklin; Biedenkopf, Nadine; Eickmann, Markus; Becker, Stephan

    2015-01-01

    Current risk assessment and risk communication of biosafety and biosecurity concerns lack a convenient metric and conceptual framework. The absence of such a systematic tool makes communication more difficult and can lead to ambiguous public perception of and response to laboratory biosafety incidents and biosecurity threats. A new 7-category scoring scale is proposed for incidents and situations in laboratories related to the handling of human and animal pathogens. The scale aims to help clarify risk categories, facilitate coordination and communication, and improve public understanding of risk related to biosafety and biosecurity.

  14. The implementation of biosecurity practices and visitor protocols on non-commercial horse properties in New Zealand.

    PubMed

    Rosanowski, S M; Rogers, C W; Cogger, N; Benschop, J; Stevenson, M A

    2012-11-01

    A survey was conducted to investigate biosecurity practices on non-commercial horse properties, to describe the number of visits by horse professionals and any protocols that visitors were required to follow before interacting with resident horses. Data were collected in November 2009 during a cross-sectional study of non-commercial horse properties, in New Zealand, selected using generalised random-tessellated stratified design and a self-administered postal questionnaire. Data were described and the associations between property-level factors and biosecurity practices were analysed using logistic regression analysis. In total there were 791 respondents from non-commercial horse properties, of which 660 (83%) answer at least one question relating to biosecurity practices. Of the respondents, 95% had at least one biosecurity practice for arriving horses. Only 31% of properties isolated horses for more than four days, and few respondents checked for pyrexia or other clinical signs of infectious disease in new horses. Moving horses from a property was associated with the implementation of biosecurity practices and practices specific to the clinical signs of respiratory disease. Overall, 79% of properties had horse professional's visit, but only 33% of respondents reported biosecurity protocols for these visitors. Most properties had some knowledge about newly arriving horses, but the effectiveness of these practices for biosecurity were questionable, as few practices would stop disease spread to resident horses. Horse professionals are likely candidates for disease spread due to contact with horses, limited visitor protocols and the frequency of visits. The development of a plan to improve biosecurity for endemic and exotic disease is recommended. Copyright © 2012 Elsevier B.V. All rights reserved.

  15. Biosecurity measures in 48 isolation facilities managing highly infectious diseases.

    PubMed

    Puro, Vincenzo; Fusco, Francesco M; Schilling, Stefan; Thomson, Gail; De Iaco, Giuseppina; Brouqui, Philippe; Maltezou, Helena C; Bannister, Barbara; Gottschalk, René; Brodt, Hans-Rheinhard; Ippolito, Giuseppe

    2012-06-01

    Biosecurity measures are traditionally applied to laboratories, but they may also be usefully applied in highly specialized clinical settings, such as the isolation facilities for the management of patients with highly infectious diseases (eg, viral hemorrhagic fevers, SARS, smallpox, potentially severe pandemic flu, and MDR- and XDR-tuberculosis). In 2009 the European Network for Highly Infectious Diseases conducted a survey in 48 isolation facilities in 16 European countries to determine biosecurity measures for access control to the facility. Security personnel are present in 39 facilities (81%). In 35 facilities (73%), entrance to the isolation area is restricted; control methods include electronic keys, a PIN system, closed-circuit TV, and guards at the doors. In 25 facilities (52%), identification and registration of all staff entering and exiting the isolation area are required. Access control is used in most surveyed centers, but specific lacks exist in some facilities. Further data are needed to assess other biosecurity aspects, such as the security measures during the transportation of potentially contaminated materials and measures to address the risk of an "insider attack."

  16. Biosecurity Measures in 48 Isolation Facilities Managing Highly Infectious Diseases

    PubMed Central

    Puro, Vincenzo; Schilling, Stefan; Thomson, Gail; De Iaco, Giuseppina; Brouqui, Philippe; Maltezou, Helena C.; Bannister, Barbara; Gottschalk, René; Brodt, Hans-Rheinhard; Ippolito, Giuseppe

    2012-01-01

    Biosecurity measures are traditionally applied to laboratories, but they may also be usefully applied in highly specialized clinical settings, such as the isolation facilities for the management of patients with highly infectious diseases (eg, viral hemorrhagic fevers, SARS, smallpox, potentially severe pandemic flu, and MDR- and XDR-tuberculosis). In 2009 the European Network for Highly Infectious Diseases conducted a survey in 48 isolation facilities in 16 European countries to determine biosecurity measures for access control to the facility. Security personnel are present in 39 facilities (81%). In 35 facilities (73%), entrance to the isolation area is restricted; control methods include electronic keys, a PIN system, closed-circuit TV, and guards at the doors. In 25 facilities (52%), identification and registration of all staff entering and exiting the isolation area are required. Access control is used in most surveyed centers, but specific lacks exist in some facilities. Further data are needed to assess other biosecurity aspects, such as the security measures during the transportation of potentially contaminated materials and measures to address the risk of an “insider attack.” PMID:22571373

  17. Biosecurity Conditions in Small Commercial Chicken Farms, Bangladesh 2011–2012

    PubMed Central

    Rimi, N. A.; Sultana, R.; Muhsina, M.; Uddin, B.; Haider, N.; Nahar, N.; Zeidner, N.; Sturm-Ramirez, K.; Luby, S. P.

    2018-01-01

    In Bangladesh, highly pathogenic avian influenza H5N1 is endemic in poultry. This study aimed to understand the biosecurity conditions and farmers’ perception of avian influenza biosecurity in Bangladeshi small commercial chicken farms. During 2011–2012, we conducted observations, in-depth interviews and group discussions with poultry farmers in 16 farms and in-depth interviews with seven local feed vendors from two districts. None of the farms were completely segregated from people, backyard poultry, other animals, households, other poultry farms or large trees. Wild birds and rodents accessed the farms for poultry feed. Farmers usually did not allow the buyers to bring egg trays inside their sheds. Spraying disinfectant in the shed and removing feces were the only regular cleaning and disinfection activities observed. All farmers sold or used untreated feces as fish feed or fertilizer. Farmers were more concerned about Newcastle disease and infectious bursal disease than about avian influenza. Farmers’ understanding about biosecurity and avian influenza was influenced by local vendors. While we seldom observed flock segregation, some farmers used measures that involved additional cost or effort to protect their flocks. These farmers could be motivated by interventions to protect their investment from diseases they consider harmful. Future interventions could explore the feasibility and effectiveness of low-cost alternative biosecurity measures. PMID:28289988

  18. Biosecurity Measures Applied in the United Arab Emirates - a Comparative Study Between Livestock and Wildlife Sectors.

    PubMed

    Chaber, A L; Saegerman, C

    2017-08-01

    In 2013, the livestock population in the UAE exceeded 4.3 million heads with sheep and goats accounting for 90% of this. The overall number of captive wild ungulates (gazelle types) is difficult to assess as there is no registration system in place or enforced in the UAE with regard to the possession of wildlife. Those animal collections, mainly owned by high-ranking families, are therefore not registered and kept far from public viewing. Nonetheless, some collections are housing more than 30 000 ungulates in one location. The primary objective of this study was to describe the biosecurity measures currently applied in UAE ungulate facilities for different wildlife and livestock sectors. A secondary objective was to use the output from this biosecurity survey to investigate which sector could be categorized into risk groups for disease introduction and spread. Between October 2014 and May 2015, biosecurity questionnaire data were collected in the Emirates of Abu Dhabi, Dubai, Ras Al Khaimah, Fujeirah, Ajman, Umm al Quwain and Sharjah from 14 wildlife collections, 30 livestock farms and 15 mixed (wildlife and livestock farms). These investigations through questionnaires allowed us to quantify and assess statistically biosecurity practices and levels for both livestock and wildlife sectors. In both sectors, biosecurity measures could be improved and only a few facilities had high biosecurity scores. The group of small unregistered farms (Ezba) represented the highest risk of disease transmission to other animals due to their lack of biosecurity awareness. © 2016 Blackwell Verlag GmbH.

  19. SurF: an innovative framework in biosecurity and animal health surveillance evaluation.

    PubMed

    Muellner, Petra; Watts, Jonathan; Bingham, Paul; Bullians, Mark; Gould, Brendan; Pande, Anjali; Riding, Tim; Stevens, Paul; Vink, Daan; Stärk, Katharina Dc

    2018-05-16

    Surveillance for biosecurity hazards is being conducted by the New Zealand Competent Authority, the Ministry for Primary Industries (MPI) to support New Zealand's biosecurity system. Surveillance evaluation should be an integral part of the surveillance life cycle, as it provides a means to identify and correct problems and to sustain and enhance the existing strengths of a surveillance system. The surveillance evaluation Framework (SurF) presented here was developed to provide a generic framework within which the MPI biosecurity surveillance portfolio, and all of its components, can be consistently assessed. SurF is an innovative, cross-sectoral effort that aims to provide a common umbrella for surveillance evaluation in the animal, plant, environment and aquatic sectors. It supports the conduct of the following four distinct components of an evaluation project: (i) motivation for the evaluation, (ii) scope of the evaluation, (iii) evaluation design and implementation and (iv) reporting and communication of evaluation outputs. Case studies, prepared by MPI subject matter experts, are included in the framework to guide users in their assessment. Three case studies were used in the development of SurF in order to assure practical utility and to confirm usability of SurF across all included sectors. It is anticipated that the structured approach and information provided by SurF will not only be of benefit to MPI but also to other New Zealand stakeholders. Although SurF was developed for internal use by MPI, it could be applied to any surveillance system in New Zealand or elsewhere. © 2018 2018 The Authors. Transboundary and Emerging Diseases Published by Blackwell Verlag GmbH.

  20. Eight strategies to engage industry in biosecurity.

    PubMed

    Gilmore, James; Lambert, Janet Lynch

    2005-01-01

    A significant portion of the domestic bio-research base-and the one most likely to provide translational research-is not engaged in biodefense. Despite the fact that more than one-third of all life science researchers are employed in commercial bio-research, fewer than 3% of the 1,500 U.S. bio-technology companies are involved in biosecurity initiatives. The bio-tech industry has largely not aligned itself to play an integral role in biosecurity, but there are a few policy changes that could dramatically alter this balance. These include engaging and motivating the bio-technology middle class, seeding secondary markets, focusing on system solutions, providing reagents and standards, aligning communications, and prioritizing translational research. By reaching out, policymakers can span the current chasm between the bio-industry and government, build a stable biodefense industrial base, establish solid working relationships, and secure better services and products. The rewards would be significant for government and industry alike.

  1. Biosafety, biosecurity and internationally mandated regulatory regimes: compliance mechanisms for education and global health security

    PubMed Central

    Sture, Judi; Whitby, Simon; Perkins, Dana

    2015-01-01

    This paper highlights the biosafety and biosecurity training obligations that three international regulatory regimes place upon states parties. The duty to report upon the existence of such provisions as evidence of compliance is discussed in relation to each regime. We argue that such mechanisms can be regarded as building blocks for the development and delivery of complementary biosafety and biosecurity teaching and training materials. We show that such building blocks represent foundations upon which life and associated scientists – through greater awareness of biosecurity concerns – can better fulfil their responsibilities to guard their work from misuse in the future. PMID:24494580

  2. Assessment of biosecurity level in small-scale broiler farms in the Western highlands of Cameroon (Central Africa).

    PubMed

    Kouam, Marc K; Jacouba, Manjeli; Nsangou, Inouss N; Teguia, Alexis

    2018-04-23

    The recent outbreak of avian influenza in the poultry sector of Cameroon has raised a concern about the level of implementation of biosecurity measures (BM) on poultry farms. Therefore, a study using a questionnaire on 102 randomly selected poultry farms was undertaken. Some measures with high adoption levels (> 90%) included "protection of airing openings of poultry barns by a wire mesh," "no external animal allowed to enter the farm," "respect of all-in all-out principle," "functional footbath," "rodent control," and "feedstuff protection from access to rodents." The least implemented measures (less than 20%) were "wearing of dedicated clothing (clean coveralls and boots) by workers," "disinfection of visitors," and "presence of storage room for dead animals." Only for "isolation" component of biosecurity, compliance with biosecurity measures was good, with more than 50% of farms having an adoption rate greater than 75%. The mean biosecurity score for the assessed farms was 19.29 ± 1.89 for a maximum score of 38 points. The score was significantly and positively correlated (p < 0.05) with the number of chicken and the geographic location of farms. The other results showed that the mean number of broiler per cycle was 550.82 ± 76 for a stocking density of 27.20 ± 6.64 birds per m 2 . In conclusion, broiler production in the Western highland is dominated by small-scale units with low level of biosecurity practices positively and significantly (p < 0.05) influenced by some production characteristics. To improve biosecurity practices in the area, efforts must focus on measures concerning "sanitation" and "traffic control" components of biosecurity.

  3. Biosecurity and Yield Improvement Technologies Are Strategic Complements in the Fight against Food Insecurity

    PubMed Central

    Cook, David C.; Fraser, Rob W.; Paini, Dean R.; Warden, Andrew C.; Lonsdale, W. Mark; De Barro, Paul J.

    2011-01-01

    The delivery of food security via continued crop yield improvement alone is not an effective food security strategy, and must be supported by pre- and post-border biosecurity policies to guard against perverse outcomes. In the wake of the green revolution, yield gains have been in steady decline, while post-harvest crop losses have increased as a result of insufficiently resourced and uncoordinated efforts to control spoilage throughout global transport and storage networks. This paper focuses on the role that biosecurity is set to play in future food security by preventing both pre- and post-harvest losses, thereby protecting crop yield. We model biosecurity as a food security technology that may complement conventional yield improvement policies if the gains in global farm profits are sufficient to offset the costs of implementation and maintenance. Using phytosanitary measures that slow global spread of the Ug99 strain of wheat stem rust as an example of pre-border biosecurity risk mitigation and combining it with post-border surveillance and invasive alien species control efforts, we estimate global farm profitability may be improved by over US$4.5 billion per annum. PMID:22022517

  4. Biosecurity and bird movement practices in upland game bird facilities in the United States.

    PubMed

    Slota, Katharine E; Hill, Ashley E; Keefe, Thomas J; Bowen, Richard A; Pabilonia, Kristy L

    2011-06-01

    Since 1996, the emergence of Asian-origin highly pathogenic avian influenza subtype H5N1 has spurred great concern for the global poultry industry. In the United States, there is concern over the potential of a foreign avian disease incursion into the country. Noncommercial poultry operations, such as upland game bird facilities in the United States, may serve as a potential source of avian disease introduction to other bird populations including the commercial poultry industry, backyard flocks, or wildlife. In order to evaluate how to prevent disease transmission from these facilities to other populations, we examined biosecurity practices and bird movement within the upland game bird industry in the United States. Persons that held a current permit to keep, breed, or release upland game birds were surveyed for information on biosecurity practices, flock and release environments, and bird movement parameters. Biosecurity practices vary greatly among permit holders. Many facilities allow for interaction between wild birds and pen-reared birds, and there is regular long-distance movement of live adult birds among facilities. Results suggest that upland game bird facilities should be targeted for biosecurity education and disease surveillance efforts.

  5. Biosecurity practices on Australian commercial layer and meat chicken farms: Performance and perceptions of farmers

    PubMed Central

    Singh, Mini; Groves, Peter; Hernandez-Jover, Marta; Barnes, Belinda; Glass, Kathryn; Moloney, Barbara; Black, Amanda; Toribio, Jenny-Ann

    2018-01-01

    This paper describes the level of adoption of biosecurity practices performed on Australian commercial chicken meat and layer farms and farmer-perceived importance of these practices. On-farm interviews were conducted on 25 free range layer farms, nine cage layer farms, nine barn layer farms, six free range meat chicken farms and 15 barn meat chicken farms in the Sydney basin bioregion and South East Queensland. There was a high level of treatment of drinking water across all farm types; town water was the most common source. In general, meat chicken farms had a higher level of adoption of biosecurity practices than layer farms. Cage layer farms had the shortest median distance between sheds (7.75m) and between sheds and waterbodies (30m). Equipment sharing between sheds was performed on 43% of free range meat chicken farms compared to 92% of free range layer farms. There was little disinfection of this shared equipment across all farm types. Footbaths and visitor recording books were used by the majority of farms for all farm types except cage layer farms (25%). Wild birds in sheds were most commonly reported in free range meat chicken farms (73%). Dogs and cats were kept across all farm types, from 56% of barn layer farms to 89% of cage layer farms, and they had access to the sheds in the majority (67%) of cage layer farms and on the range in some free range layer farms (44%). Most biosecurity practices were rated on average as ‘very important’ by farmers. A logistic regression analysis revealed that for most biosecurity practices, performing a practice was significantly associated with higher perceived farmer importance of that biosecurity practice. These findings help identify farm types and certain biosecurity practices with low adoption levels. This information can aid decision-making on efforts used to improve adoption levels. PMID:29668707

  6. Biosecurity practices on Australian commercial layer and meat chicken farms: Performance and perceptions of farmers.

    PubMed

    Scott, Angela Bullanday; Singh, Mini; Groves, Peter; Hernandez-Jover, Marta; Barnes, Belinda; Glass, Kathryn; Moloney, Barbara; Black, Amanda; Toribio, Jenny-Ann

    2018-01-01

    This paper describes the level of adoption of biosecurity practices performed on Australian commercial chicken meat and layer farms and farmer-perceived importance of these practices. On-farm interviews were conducted on 25 free range layer farms, nine cage layer farms, nine barn layer farms, six free range meat chicken farms and 15 barn meat chicken farms in the Sydney basin bioregion and South East Queensland. There was a high level of treatment of drinking water across all farm types; town water was the most common source. In general, meat chicken farms had a higher level of adoption of biosecurity practices than layer farms. Cage layer farms had the shortest median distance between sheds (7.75m) and between sheds and waterbodies (30m). Equipment sharing between sheds was performed on 43% of free range meat chicken farms compared to 92% of free range layer farms. There was little disinfection of this shared equipment across all farm types. Footbaths and visitor recording books were used by the majority of farms for all farm types except cage layer farms (25%). Wild birds in sheds were most commonly reported in free range meat chicken farms (73%). Dogs and cats were kept across all farm types, from 56% of barn layer farms to 89% of cage layer farms, and they had access to the sheds in the majority (67%) of cage layer farms and on the range in some free range layer farms (44%). Most biosecurity practices were rated on average as 'very important' by farmers. A logistic regression analysis revealed that for most biosecurity practices, performing a practice was significantly associated with higher perceived farmer importance of that biosecurity practice. These findings help identify farm types and certain biosecurity practices with low adoption levels. This information can aid decision-making on efforts used to improve adoption levels.

  7. Can biosecurity and local network properties predict pathogen species richness in the salmonid industry?

    PubMed Central

    More, Simon J.; Geoghegan, Fiona; McManus, Catherine; Hill, Ashley E.; Martínez-López, Beatriz

    2018-01-01

    Salmonid farming in Ireland is mostly organic, which implies limited disease treatment options. This highlights the importance of biosecurity for preventing the introduction and spread of infectious agents. Similarly, the effect of local network properties on infection spread processes has rarely been evaluated. In this paper, we characterized the biosecurity of salmonid farms in Ireland using a survey, and then developed a score for benchmarking the disease risk of salmonid farms. The usefulness and validity of this score, together with farm indegree (dichotomized as ≤ 1 or > 1), were assessed through generalized Poisson regression models, in which the modeled outcome was pathogen richness, defined here as the number of different diseases affecting a farm during a year. Seawater salmon (SW salmon) farms had the highest biosecurity scores with a median (interquartile range) of 82.3 (5.4), followed by freshwater salmon (FW salmon) with 75.2 (8.2), and freshwater trout (FW trout) farms with 74.8 (4.5). For FW salmon and trout farms, the top ranked model (in terms of leave-one-out information criteria, looic) was the null model (looic = 46.1). For SW salmon farms, the best ranking model was the full model with both predictors and their interaction (looic = 33.3). Farms with a higher biosecurity score were associated with lower pathogen richness, and farms with indegree > 1 (i.e. more than one fish supplier) were associated with increased pathogen richness. The effect of the interaction between these variables was also important, showing an antagonistic effect. This would indicate that biosecurity effectiveness is achieved through a broader perspective on the subject, which includes a minimization in the number of suppliers and hence in the possibilities for infection to enter a farm. The work presented here could be used to elaborate indicators of a farm’s disease risk based on its biosecurity score and indegree, to inform risk-based disease surveillance and

  8. Can biosecurity and local network properties predict pathogen species richness in the salmonid industry?

    PubMed

    Yatabe, Tadaishi; More, Simon J; Geoghegan, Fiona; McManus, Catherine; Hill, Ashley E; Martínez-López, Beatriz

    2018-01-01

    Salmonid farming in Ireland is mostly organic, which implies limited disease treatment options. This highlights the importance of biosecurity for preventing the introduction and spread of infectious agents. Similarly, the effect of local network properties on infection spread processes has rarely been evaluated. In this paper, we characterized the biosecurity of salmonid farms in Ireland using a survey, and then developed a score for benchmarking the disease risk of salmonid farms. The usefulness and validity of this score, together with farm indegree (dichotomized as ≤ 1 or > 1), were assessed through generalized Poisson regression models, in which the modeled outcome was pathogen richness, defined here as the number of different diseases affecting a farm during a year. Seawater salmon (SW salmon) farms had the highest biosecurity scores with a median (interquartile range) of 82.3 (5.4), followed by freshwater salmon (FW salmon) with 75.2 (8.2), and freshwater trout (FW trout) farms with 74.8 (4.5). For FW salmon and trout farms, the top ranked model (in terms of leave-one-out information criteria, looic) was the null model (looic = 46.1). For SW salmon farms, the best ranking model was the full model with both predictors and their interaction (looic = 33.3). Farms with a higher biosecurity score were associated with lower pathogen richness, and farms with indegree > 1 (i.e. more than one fish supplier) were associated with increased pathogen richness. The effect of the interaction between these variables was also important, showing an antagonistic effect. This would indicate that biosecurity effectiveness is achieved through a broader perspective on the subject, which includes a minimization in the number of suppliers and hence in the possibilities for infection to enter a farm. The work presented here could be used to elaborate indicators of a farm's disease risk based on its biosecurity score and indegree, to inform risk-based disease surveillance and control

  9. Assessment of producers' response to Salmonella biosecurity issues and uptake of advice on laying hen farms in England and Wales.

    PubMed

    Gosling, R J; Martelli, F; Wintrip, A; Sayers, A R; Wheeler, K; Davies, R H

    2014-01-01

    High standards of biosecurity are known to reduce the risk of disease outbreaks; however, uptake of advice and implementation of biosecurity measures are dependent on many factors. This study assessed the uptake of targeted biosecurity advice by 60 laying hen farms provided during biosecurity audit visits. Advice was provided as bullet point cards focusing on specific areas identified as benefitting from improvement. These covered site entrance, site tidiness, vaccination, boot hygiene, hand hygiene, house tidiness, rodent control, fly control, red mite control and cleaning and disinfection between flocks. Background knowledge of Salmonella and biosecurity and farmers' willingness and intent to implement additional measures were assessed. About 50% of the principal decision-makers had basic background knowledge of Salmonella, with 22% considered well informed; almost all agreed that biosecurity could impact on Salmonella control and many appeared willing to implement additional biosecurity measures. Sixty-three per cent of study farms were categorised using the Defra Farmer Segmentation Model as Modern Family Businesses (MFBs), with 7-11% of farms being categorised as Custodian, Lifestyle Choice, Pragmatist or Challenged Enterprise; however, categorisation, did not determine uptake of advice. The most frequently used advice cards were boot hygiene, red mite control, hand hygiene, site entrance and cleaning and disinfection; uptake of advice ranged from 54 to 80% depending on the advice card. Uptake of advice by the farmers was encouraging, especially considering it was being provided by people other than their usual source of biosecurity information. Those who did not implement the recommended measures cited cost, difficulty of enforcement and practicality as the main reasons. However, the positive uptake of advice and implementation of recommended measures by many farmers demonstrates that targeted advice, discussed face to face with farmers, on a small number of

  10. Invertebrate Biosecurity Challenges in High-Productivity Grassland: The New Zealand Example

    PubMed Central

    Goldson, Stephen L.; Barratt, Barbara I. P.; Armstrong, Karen F.

    2016-01-01

    To protect productive grasslands from pests and diseases, effective pre- and at-border planning and interventions are necessary. Biosecurity failure inevitably requires expensive and difficult eradication, or long-term and often quite ineffective management strategies. This is compared to the early intervention more likely for sectors where there is public and political interest in plants of immediate economic and/or social value, and where associated pests are typically located above-ground on host plantings of relatively limited distribution. Here, biosecurity surveillance and responses can be readily designed. In contrast, pastures comprising plants of low inherent unit value create little, if any, esthetic interest. Yet, given the vast extent of pasture in New Zealand and the value of the associated industries, these plants are of immense economic importance. Compounding this is the invasibility of New Zealand’s pastoral ecosystems through a lack of biotic resistance to incursion and invasion. Further, given the sheer area of pasture, intervention options are limited because of costs per unit area and the potential for pollution if pesticides are used. Biosecurity risk for pastoral products differs from, say, that of fruit where at least part of an invasive pathway can be recognized and risks assessed. The ability to do this via pastoral sector pathways is much reduced, since risk organisms more frequently arrive via hitchhiker pathways which are diffuse and varied. Added to this pasture pests within grassland ecosystems are typically cryptic, often with subterranean larval stages. Such characteristics make detection and response particularly difficult. The consequences of this threaten to add to the already-increasing stressors of production intensification and climate change. This review explores the unique challenges faced by pasture biosecurity and what may be done to confront existing difficulties. While there is no silver bullet, and limited opportunity

  11. [Biosecurity and clinical care nursing: contributions for the promotion of worker's health].

    PubMed

    Gallas, Samanta Rauber; Fontana, Rosane Teresinha

    2010-01-01

    Qualitative study that aimed at investigating concepts and practices of nursing technicians on biosecurity and its interface with biological hazards, with 20 workers developed a clinical care unit of a hospital in the interior of Rio Grande do Sul. Data were collected through interviews and systematic observation. Thematic analysis was the methodology used for data processing. The negligence of its employees on the use of individual protection equipment and work overload are risk factors for accidents with biological material. Suggested that partnerships between the actors involved in caring for the construction of healthy environments and accountability for negligence on biosecurity.

  12. On-farm characteristics and biosecurity protocols for small-scale swine producers in eastern Australia.

    PubMed

    Schembri, N; Hernandez-Jover, M; Toribio, J-A L M L; Holyoake, P K

    2015-01-01

    Pigs are considered high risk for the introduction and spread of foot and mouth disease (FMD) in Australia. Facilities where animals from different origins are commingled, such as saleyards, pose a high risk for disease spread. Sound on-farm management practices and biosecurity protocols are the first line of defence against a potential on-farm disease outbreak. This study evaluated the practices of 104 producers (vendors who sold pigs and purchasers of live pigs for grow-out) who traded pigs at 6 peri-urban and rural saleyards in eastern Australia. Specifically, management and on-farm biosecurity practices were assessed using an in-depth questionnaire. Univariable and multivariable logistic regression analyses were used to investigate (1) producer associations: producer type, State, motivation to keep pigs, farm type, gender, years having owned pigs, and the acquisition of formal livestock qualifications; and (2) pig associations: herd size, housing, management (husbandry and feeding) practices and biosecurity (including pig movement) practices. Backyard operations (<20 sows) were undertaken by 60.6% of participants, followed by small-scale pig operations (28.8%; 21-100 sows). Few producers (16.3%) reported residing in close proximity (<5 km) to commercial operations; however, less rural producers had neighbouring hobby pig operations within 5 km of their property (P=0.033). Motivation for keeping pigs was significantly associated with a number of biosecurity practices. Producers who kept pigs for primary income were more likely to provide footwear precautions (P=0.007) and ask visitors about prior pig contacts (P=0.004). Approximately 40% of backyard and small-scale producers reported not having any quarantine practices in place for incoming pigs, compared to only 9.1% among larger producers. The main reasons cited for not adopting on-farm biosecurity practices in this study included having no need on their property (43.1%) and a lack of information and support

  13. Connecting Different Data Sources to Assess the Interconnections between Biosecurity, Health, Welfare, and Performance in Commercial Pig Farms in Great Britain.

    PubMed

    Pandolfi, Fanny; Edwards, Sandra A; Maes, Dominiek; Kyriazakis, Ilias

    2018-01-01

    This study aimed to provide an overview of the interconnections between biosecurity, health, welfare, and performance in commercial pig farms in Great Britain. We collected on-farm data about the level of biosecurity and animal performance in 40 fattening pig farms and 28 breeding pig farms between 2015 and 2016. We identified interconnections between these data, slaughterhouse health indicators, and welfare indicator records in fattening pig farms. After achieving the connections between databases, a secondary data analysis was performed to assess the interconnections between biosecurity, health, welfare, and performance using correlation analysis, principal component analysis, and hierarchical clustering. Although we could connect the different data sources the final sample size was limited, suggesting room for improvement in database connection to conduct secondary data analyses. The farm biosecurity scores ranged from 40 to 90 out of 100, with internal biosecurity scores being lower than external biosecurity scores. Our analysis suggested several interconnections between health, welfare, and performance. The initial correlation analysis showed that the prevalence of lameness and severe tail lesions was associated with the prevalence of enzootic pneumonia-like lesions and pyaemia, and the prevalence of severe body marks was associated with several disease indicators, including peritonitis and milk spots ( r  > 0.3; P  < 0.05). Higher average daily weight gain (ADG) was associated with lower prevalence of pleurisy ( r  > 0.3; P  < 0.05), but no connection was identified between mortality and health indicators. A subsequent cluster analysis enabled identification of patterns which considered concurrently indicators of health, welfare, and performance. Farms from cluster 1 had lower biosecurity scores, lower ADG, and higher prevalence of several disease and welfare indicators. Farms from cluster 2 had higher biosecurity scores than cluster 1, but a

  14. Informal value chain actors' knowledge and perceptions about zoonotic diseases and biosecurity in Kenya and the importance for food safety and public health.

    PubMed

    Nyokabi, Simon; Birner, Regina; Bett, Bernard; Isuyi, Linda; Grace, Delia; Güttler, Denise; Lindahl, Johanna

    2018-03-01

    Zoonotic diseases, transmitted from animals to humans, are a public health challenge in developing countries. Livestock value chain actors have an important role to play as the first line of defence in safeguarding public health. However, although the livelihood and economic impacts of zoonoses are widely known, adoption of biosecurity measures aimed at preventing zoonoses is low, particularly among actors in informal livestock value chains in low and middle-income countries. The main objective of this study was to investigate knowledge of zoonoses and adoption of biosecurity measures by livestock and milk value chain actors in Bura, Tana River County, in Kenya, where cattle, camels, sheep and goats are the main livestock kept. The study utilised a mixed methods approach, with a questionnaire survey administered to 154 value chain actors. Additional information was elicited through key informant interviews and participatory methods with relevant stakeholders outside the value chain. Our results found low levels of knowledge of zoonoses and low levels of adherence to food safety standards, with only 37% of milk traders knowing about brucellosis, in spite of a sero-prevalence of 9% in the small ruminants tested in this study, and no slaughterhouse worker knew about Q fever. Actors had little formal education (between 0 and 10%) and lacked training in food safety and biosecurity measures. Adoption of biosecurity measures by value chain actors was very low or non-existent, with only 11% of butchers wearing gloves. There was a gendered dimension, evidenced by markedly different participation in value chains and lower adoption rates and knowledge levels among female actors. Finally, cultural and religious practices were shown to play an important role in exposure and transmission of diseases, influencing perceptions and attitudes to risks and adoption of biosecurity measures.

  15. Assessing the Need for an On-Line Educational Module for Volunteer Leaders on Bio-Security in Washington State 4-H Livestock Projects

    ERIC Educational Resources Information Center

    Stevenson, Jill L.; Moore, Dale A.; Newman, Jerry; Schmidt, Janet L.; Smith, Sarah M.; Smith, Jean; Kerr, Susan; Wallace, Michael; BoyEs, Pat

    2011-01-01

    4-H livestock projects present disease transmission risks that can be reduced by the use of bio-security practices. The responsibility of teaching bio-security to youth belongs primarily to volunteer leaders, who may not be aware of the importance of these practices. A needs assessment for an online educational module about bio-security revealed…

  16. Laboratory Biosafety and Biosecurity Risk Assessment Technical Guidance Document

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Astuto-Gribble, Lisa M; Caskey, Susan Adele

    2014-07-01

    The purpose of this document is threefold: 1) to describe the laboratory bio safety and biosecurity risk assessment process and its conceptual framework; 2) provide detailed guidance and suggested methodologies on how to conduct a risk assessment; and 3) present some practical risk assessment process strategies using realistic laboratory scenarios.

  17. Medical Tourism, Medical Migration, and Global Justice: Implications for Biosecurity in a Globalized World.

    PubMed

    Cohen, I Glenn

    2017-05-01

    We live in the age of globalization. In medicine, that globalization has brought many benefits such as the diffusion of technology and the spread of health care training, but it has also brought threats to biosecurity. This article examines how medical tourism and medical migration pose risks to biosecurity. It also argues that designing legal responses to these risks requires not only technical competence but also a theory of global justice to guide that design. © The Author 2017. Published by Oxford University Press; all rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Biosecurity management recommendations for rinderpest laboratories

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brodsky, Benjamin H; Caskey, Susan Adele; Arndt, William

    2014-10-01

    Rinderpest is a virus that can affect cattle and other even toes ungulates; evidence of outbreaks from over 10,000 years ago highlights the potential impact of this virus. During the 18th century, Rinderpest caused huge losses in cattle throughout Europe. Starting in the mid 1900’s vaccination efforts seemed feasible and work was initiated to vaccinate large populations of cattle. Walter Plowright received numerous awards for updating the Rinderpest vaccine which many believed would be the key to eradication. Vaccination of the disease lead to a massive drop in outbreaks and the last confirmed case of Rinderpest in Asia was inmore » 2000 and in Africa in 2001.1 At this point, Rinderpest has been declared eradicated from nature. However, stocks of the virus are still in many laboratories.2 Rinderpest was investigated as a biological weapon agent during the Second World War. However, following WWII, rinderpest was not considered a high risk as a biological weapon as there was no direct military advantage. Now, with the concern of the use of biological agents as weapons in acts of terrorism, concern regarding rinderpest has resurfaced. Since the eradication of this virus, cattle populations are highly susceptibility to the virus and the economic impacts would be significant. This paper will discuss the specific nature of the terrorism risks associated with rinderpest; and based upon those risks provide recommendations regarding biosecurity management. The biosecurity management measures will be defined in a manner to align with the CWA 15793: the laboratory biorisk management document.« less

  19. Mechanisms for the prevention of marine bioinvasions for better biosecurity.

    PubMed

    Hewitt, Chad L; Campbell, Marnie L

    2007-01-01

    Biosecurity management allows countries to meet a number of international obligations and provides some protection from potential degradation of environmental, economic, social and cultural values. Ocean governance relies on the precepts of ecologically sustainable development to manage the multiple uses in the coastal zone. The increasing reliance on aquaculture to provide food security and economic development has led to an increase in the use of non-native target species grown as food sources. Increased economic activity has led to shifting trade patterns and increased efficiencies in vessels with the resulting increase in the number of introduced marine species via ballast water and hull fouling. Herein we review the different marine biosecurity strategies and legislation that have been implemented internationally and locally that aid in preventing and managing introduced marine species, with some attention to Australia and New Zealand as examples. Typical tools being used include quarantine, Import Health Standards, voluntary cleaning guidelines, and risk assessment, all of which aim to prevent introductions.

  20. Investigation of biosecurity risks associated with the feed delivery: A pilot study.

    PubMed

    Bottoms, Kate; Dewey, Cate; Richardson, Karen; Poljak, Zvonimir

    2015-05-01

    This study explored potential biosecurity issues related to the delivery of feed to commercial farms. A pilot study was conducted to collect information about the day-to-day feed delivery, including biosecurity concerns at the level of the feed truck, the driver, and the farm. In addition, a reusable rubber boot was tested in an effort to increase the proportion of farms at which truck drivers wore clean footwear, and to explore an alternative to the standard plastic disposable boots that may be unsafe in winter conditions. Most farms did well in terms of proper dead-stock management and keeping the farm lane and feed bin areas clean. The provision of reusable rubber boots significantly increased the proportion of deliveries in which the driver wore clean footwear.

  1. African swine fever outbreak on a medium-sized farm in Uganda: biosecurity breaches and within-farm virus contamination.

    PubMed

    Chenais, Erika; Sternberg-Lewerin, Susanna; Boqvist, Sofia; Liu, Lihong; LeBlanc, Neil; Aliro, Tonny; Masembe, Charles; Ståhl, Karl

    2017-02-01

    In Uganda, a low-income country in east Africa, African swine fever (ASF) is endemic with yearly outbreaks. In the prevailing smallholder subsistence farming systems, farm biosecurity is largely non-existent. Outbreaks of ASF, particularly in smallholder farms, often go unreported, creating significant epidemiological knowledge gaps. The continuous circulation of ASF in smallholder settings also creates biosecurity challenges for larger farms. In this study, an on-going outbreak of ASF in an endemic area was investigated on farm level, including analyses of on-farm environmental virus contamination. The study was carried out on a medium-sized pig farm with 35 adult pigs and 103 piglets or growers at the onset of the outbreak. Within 3 months, all pigs had died or were slaughtered. The study included interviews with farm representatives as well as biological and environmental sampling. ASF was confirmed by the presence of ASF virus (ASFV) genomic material in biological (blood, serum) and environmental (soil, water, feed, manure) samples by real-time PCR. The ASFV-positive biological samples confirmed the clinical assessment and were consistent with known virus characteristics. Most environmental samples were found to be positive. Assessment of farm biosecurity, interviews, and the results from the biological and environmental samples revealed that breaches and non-compliance with biosecurity protocols most likely led to the introduction and within-farm spread of the virus. The information derived from this study provides valuable insight regarding the implementation of biosecurity measures, particularly in endemic areas.

  2. Associations between biosecurity and outbreaks of canine distemper on Danish mink farms in 2012-2013.

    PubMed

    Gregers-Jensen, Louise; Agger, Jens Frederik; Hammer, Anne Sofie Vedsted; Andresen, Lars; Chrièl, Mariann; Hagberg, Emma; Jensen, Mette Kragh; Hansen, Mette Sif; Hjulsager, Charlotte Kristiane; Struve, Tina

    2015-09-30

    During 8 months from July 2012 to February 2013, a major outbreak of canine distemper involving 64 mink farms occurred on the Danish peninsula of Jutland. The canine distemper outbreak was associated with exposure of farmed mink to infected wild carnivores and could represent a deficit in biosecurity on the mink farms. The aim of this study was to investigate the extent and association of specific biosecurity measures with the outbreak. The study was carried out in an epidemiological case-control design. The case group consisted of the 61 farms, which had a confirmed outbreak of canine distemper from July 2012 to February 2013. The control group included 54 farms without an outbreak of canine distemper in 2012 or 2013, selected as the closest geographical neighbour to a case farm. The results showed that significantly more control than case farms had vaccinated their mink against canine distemper virus. Mortality was only assessed on the case farms, and there was a non-significantly lower mortality on vaccinated farms than on the non-vaccinated farms. Furthermore, the proportion of farms with observations of wild red foxes (Vulpes vulpes) inside the farm enclosures were larger for case farms, indicating that the control farms had a better biosecurity or were not equally exposed to canine distemper virus. Generally, all farms had very few specific precautions at the gate entrance in respect to human visitors as well as animals. The use of biosecurity measures was very variable in both case and control farms. Not using plastic boot covers, presence of dogs and cats, presence of demarcated area for changing clothes when entering and leaving the farm area and presence of hand washing facilities significantly lowered the odds of the farm having a canine distemper virus outbreak. The results of the study indicate that consistent use of correct vaccination strategies, implementation of biosecurity measures and limiting human and animal access to the mink farm can be

  3. Investigation of biosecurity risks associated with the feed delivery: A pilot study

    PubMed Central

    Bottoms, Kate; Dewey, Cate; Richardson, Karen; Poljak, Zvonimir

    2015-01-01

    This study explored potential biosecurity issues related to the delivery of feed to commercial farms. A pilot study was conducted to collect information about the day-to-day feed delivery, including biosecurity concerns at the level of the feed truck, the driver, and the farm. In addition, a reusable rubber boot was tested in an effort to increase the proportion of farms at which truck drivers wore clean footwear, and to explore an alternative to the standard plastic disposable boots that may be unsafe in winter conditions. Most farms did well in terms of proper dead-stock management and keeping the farm lane and feed bin areas clean. The provision of reusable rubber boots significantly increased the proportion of deliveries in which the driver wore clean footwear. PMID:25969585

  4. Biosecurity measures to reduce influenza infections in military barracks in Ghana.

    PubMed

    Agbenohevi, Prince Godfred; Odoom, John Kofi; Bel-Nono, Samuel; Nyarko, Edward Owusu; Alhassan, Mahama; Rodgers, David; Danso, Fenteng; Suu-Ire, Richard D; Bonney, Joseph Humphrey Kofi; Aboagye, James; Kronmann, Karl C; Duplessis, Chris; Oyofo, Buhari Anthony; Ampofo, William Kwabena

    2015-01-23

    Military barracks in Ghana have backyard poultry populations but the methods used here involve low biosecurity measures and high risk zoonosis such as avian influenza A viruses or Newcastle disease. We assessed biosecurity measures intended to minimize the risk of influenza virus infection among troops and poultry keepers in military barracks. We educated troops and used a questionnaire to collect information on animal populations and handling practices from 168 individuals within 203 households in military barracks. Cloacal and tracheal samples were taken from 892 healthy domestic and domesticated wild birds, 91 sick birds and 6 water samples for analysis using molecular techniques for the detection of influenza A virus. Of the 1090 participants educated and 168 that responded to a questionnaire, 818 (75%) and 129 (76.8%) respectively have heard of pandemic avian influenza and the risks associated with its infection. Even though no evidence of the presence of avian influenza infection was found in the 985 birds sampled, only 19.5% of responders indicated they disinfect their coops regularly and 28% wash their hands after handling their birds. Vaccination of birds and use of personal protective clothing while handling the birds were low putting the people at risk. Though some efforts have been made to improve biosecurity practices, interventions that help to protect the poultry flock from direct contact have to be practiced. Basic hygiene like washing of hands with soap and running water and regular cleaning of chicken coops are needed to prevent the spread of diseases among birds and between birds and humans.

  5. Review of transmission routes of 24 infectious diseases preventable by biosecurity measures and comparison of the implementation of these measures in pig herds in six European countries.

    PubMed

    Filippitzi, M E; Brinch Kruse, A; Postma, M; Sarrazin, S; Maes, D; Alban, L; Nielsen, L R; Dewulf, J

    2018-04-01

    This study aimed to review the transmission routes of important infectious pig diseases and to translate these into biosecurity measures preventing or reducing the transmission between and within pig herds. Furthermore, it aimed to identify the level of implementation of these measures in different European countries and discuss the observed variations to identify potentials for improvement. First, a literature review was performed to show which direct and indirect transmission routes of 24 infectious pig diseases can be prevented through different biosecurity measures. Second, a quantitative analysis was performed using the Biocheck.UGent™, a risk-based scoring system to evaluate biosecurity in pig herds, to obtain an insight into the implementation of these biosecurity measures. The database contained farm-specific biosecurity data from 574 pig farms in Belgium, Denmark, France, Germany, the Netherlands and Sweden, entered between January 2014 and January 2016. Third, a qualitative analysis based on a review of literature and other relevant information resources was performed for every subcategory of internal and external biosecurity in the Biocheck.UGent™ questionnaire. The quantitative analysis indicated that at the level of internal, external and overall biosecurity, Denmark had a significantly distinct profile with higher external biosecurity scores and less variation than the rest of the countries. This is likely due to a widely used specific pathogen-free (SPF) system with extensive focus on biosecurity since 1971 in Denmark. However, the observed pattern may also be attributed to differences in data collection methods. The qualitative analysis identified differences in applied policies, legislation, disease status, pig farm density, farming culture and habits between countries that can be used for shaping country-specific biosecurity advice to attain improved prevention and control of important pig diseases in European pig farms. © 2017 Blackwell

  6. Swedish Farmers’ Opinions about Biosecurity and Their Intention to Make Professionals Use Clean Protective Clothing When Entering the Stable

    PubMed Central

    Nöremark, Maria; Sternberg Lewerin, Susanna; Ernholm, Linda; Frössling, Jenny

    2016-01-01

    The study was part of a series of studies aiming to increase knowledge about spread and prevention of livestock diseases in Sweden. A specific biosecurity behavior, i.e., making professionals (e.g., veterinarian, repairman, livestock transporter) wear clean protective clothing when entering the stables was investigated through focus groups and a questionnaire survey. This behavior was seen as a proxy for other biosecurity behaviors. As part of questionnaire development, three focus group discussions with a total of 11 participating livestock farmers were held. The questionnaire was based on the model of Theory of Planned Behavior. Response was received from 2,081 farmers. In the focus groups, farmers expressed a willingness to provide visitors with clean protective clothing. However, some had experienced difficulties in making veterinarians use protective clothing, and mentioned a reluctance to correct their veterinarians. The participants mostly focused on diseases regulated by control programs, especially Salmonella. In parts, participants were well informed but some showed a lack of knowledge concerning routes of disease spread. They also mentioned external factors that made them deviate from biosecurity recommendations. Farmers called for biosecurity advice with focus on cost–benefit return. Among survey respondents, the intention to make visitors wear protective clothing was moderate. Analysis of underlying elements showed that a majority of farmers (88%) had a neutral attitude, i.e., they were neither in favor nor against this behavior. Measures of subjective norm indicated a varying degree of social pressure among respondents. However, the majority (63%) indicated a strong behavioral control, thus suggesting that they could make visitors use protective clothing if they wanted to. Although most farmers (84%) indicated a strong willingness to comply with the opinion of their veterinarians in biosecurity matters, 30% replied that their farm veterinarian is

  7. [Biosafety and biosecurity in the medical laboratory. Update and trends].

    PubMed

    Ionescu, G; Neguţ, M; Combiescu, A A

    2007-01-01

    Biosafety includes the protective measures against the risks of contamination with pathogen germs in the laboratories that handle pathogens, or stock or manipulate potentially contaminated products, or perform microbiological tests for medical or scientific research purposes, as well as the means of protecting the environment and the human collectivities against hazard contaminations that have as starting point these laboratories. Besides, lately, a new notion emerged, that of biosecurity, which refers to the sum of measures designed to protect workers, environment and population against the loss, theft, use and release in the environment of pathogenic biological agents. The work overviews the present concerns for the regulation of these two notions and the way in which a system for the management of the biological risks in a laboratory that handles pathogens should be documented and implemented. The need for the continuous professional training of the staff and for the establishment of individual and collective responsibilities for preventing biosafety incidents and trespassing biosecurity rules are as well emphasized. The main biosafety measures are pointed out and a series of considerations regarding biosafety and bioterrorism in correlation with the medical laboratory are as well mentioned.

  8. Exploring expert opinion on the practicality and effectiveness of biosecurity measures on dairy farms in the United Kingdom using choice modeling.

    PubMed

    Shortall, Orla; Green, Martin; Brennan, Marnie; Wapenaar, Wendela; Kaler, Jasmeet

    2017-03-01

    Biosecurity, defined as a series of measures aiming to stop disease-causing agents entering or leaving an area where farm animals are present, is very important for the continuing economic viability of the United Kingdom dairy sector, and for animal welfare. This study gathered expert opinion from farmers, veterinarians, consultants, academics, and government and industry representatives on the practicality and effectiveness of different biosecurity measures on dairy farms. The study used best-worst scaling, a technique that allows for greater discrimination between choices and avoids the variability in interpretation associated with other methods, such as Likert scales and ranking methods. Keeping a closed herd was rated as the most effective measure overall, and maintaining regular contact with the veterinarian was the most practical measure. Measures relating to knowledge, planning, and veterinary involvement; buying-in practices; and quarantine and treatment scored highly for effectiveness overall. Measures relating to visitors, equipment, pest control, and hygiene scored much lower for effectiveness. Overall, measures relating to direct animal-to-animal contact scored much higher for effectiveness than measures relating to indirect disease transmission. Some of the most effective measures were also rated as the least practical, such as keeping a closed herd and avoiding nose-to-nose contact between contiguous animals, suggesting that real barriers exist for farmers when implementing biosecurity measures on dairy farms. We observed heterogeneity in expert opinion on biosecurity measures; for example, veterinarians rated the effectiveness of consulting the veterinarian on biosecurity significantly more highly than dairy farmers, suggesting a greater need for veterinarians to promote their services on-farm. Still, both groups rated it as a practical measure, suggesting that the farmer-veterinarian relationship holds some advantages for the promotion of

  9. Use of stakeholder analysis to inform risk communication and extension strategies for improved biosecurity amongst small-scale pig producers.

    PubMed

    Hernández-Jover, M; Gilmour, J; Schembri, N; Sysak, T; Holyoake, P K; Beilin, R; Toribio, J-A L M L

    2012-05-01

    Extension and communication needs amongst small-scale pig producers, described as pig producers with less than 100 sows, have been previously identified. These producers, who are believed to pose a biosecurity risk to commercial livestock industries, are characterized by a lack of formal networks, mistrust of authorities, poor disease reporting behaviour and motivational diversity, and reliance on other producers, veterinarians and family for pig health and production advice. This paper applies stakeholder identification and analysis tools to determine stakeholders' influence and interest on pig producers' practices. Findings can inform a risk communication process and the development of an extension framework to increase producers' engagement with industry and their compliance with biosecurity standards and legislation in Australia. The process included identification of stakeholders, their issues of concerns regarding small-scale pig producers and biosecurity and their influence and interest in each of these issues. This exercise identified the capacity of different stakeholders to influence the outcomes for each issue and assessed their success or failure to do so. The disconnection identified between the level of interest and influence suggests that government and industry need to work with the small-scale pig producers and with those who have the capacity to influence them. Successful biosecurity risk management will depend on shared responsibility and building trust amongst stakeholders. Flow-on effects may include legitimating the importance of reporting and compliance systems and the co-management of risk. Compliance of small-scale pig producers with biosecurity industry standards and legislation will reduce the risks of entry and spread of exotic diseases in Australia. Copyright © 2011 Elsevier B.V. All rights reserved.

  10. Existential Risk and Cost-Effective Biosecurity

    PubMed Central

    Snyder-Beattie, Andrew

    2017-01-01

    In the decades to come, advanced bioweapons could threaten human existence. Although the probability of human extinction from bioweapons may be low, the expected value of reducing the risk could still be large, since such risks jeopardize the existence of all future generations. We provide an overview of biotechnological extinction risk, make some rough initial estimates for how severe the risks might be, and compare the cost-effectiveness of reducing these extinction-level risks with existing biosecurity work. We find that reducing human extinction risk can be more cost-effective than reducing smaller-scale risks, even when using conservative estimates. This suggests that the risks are not low enough to ignore and that more ought to be done to prevent the worst-case scenarios. PMID:28806130

  11. African civil society initiatives to drive a biobanking, biosecurity and infrastructure development agenda in the wake of the West African Ebola outbreak

    PubMed Central

    Abayomi, Akin; Gevao, Sahr; Conton, Brian; Deblasio, Pasquale; Katz, Rebecca

    2016-01-01

    This paper describes the formation of a civil society consortium, spurred to action by frustration over the Ebola crises, to facilitate the development of infrastructure and frameworks including policy development to support a harmonized, African approach to health crises on the continent. The Global Emerging Pathogens Treatment Consortium, or GET, is an important example of how African academics, scientists, clinicians and civil society have come together to initiate policy research, multilevel advocacy and implementation of initiatives aimed at building African capacity for timely and effective mitigations strategies against emerging infectious and neglected pathogens, with a focus on biobanking and biosecurity. The consortium has been able to establish it self as a leading voice, drawing attention to scientific infrastructure gaps, the importance of cultural sensitivities, and the power of community engagement. The GET consortium demonstrates how civil society can work together, encourage government engagement and strengthen national and regional efforts to build capacity. PMID:28154625

  12. African civil society initiatives to drive a biobanking, biosecurity and infrastructure development agenda in the wake of the West African Ebola outbreak.

    PubMed

    Abayomi, Akin; Gevao, Sahr; Conton, Brian; Deblasio, Pasquale; Katz, Rebecca

    2016-01-01

    This paper describes the formation of a civil society consortium, spurred to action by frustration over the Ebola crises, to facilitate the development of infrastructure and frameworks including policy development to support a harmonized, African approach to health crises on the continent. The Global Emerging Pathogens Treatment Consortium, or GET, is an important example of how African academics, scientists, clinicians and civil society have come together to initiate policy research, multilevel advocacy and implementation of initiatives aimed at building African capacity for timely and effective mitigations strategies against emerging infectious and neglected pathogens, with a focus on biobanking and biosecurity. The consortium has been able to establish it self as a leading voice, drawing attention to scientific infrastructure gaps, the importance of cultural sensitivities, and the power of community engagement. The GET consortium demonstrates how civil society can work together, encourage government engagement and strengthen national and regional efforts to build capacity.

  13. Use of Bayesian Belief Network techniques to explore the interaction of biosecurity practices on the probability of porcine disease occurrence in Canada.

    PubMed

    Cox, Ruth; Revie, Crawford W; Hurnik, Daniel; Sanchez, Javier

    2016-09-01

    Identification and quantification of pathogen threats need to be a priority for the Canadian swine industry so that resources can be focused where they will be most effective. Here we create a tool based on a Bayesian Belief Network (BBN) to model the interaction between biosecurity practices and the probability of occurrence of four different diseases on Canadian swine farms. The benefits of using this novel approach, in comparison to other methods, is that it enables us to explore both the complex interaction and the relative importance of biosecurity practices on the probability of disease occurrence. In order to build the BBN we used two datasets. The first dataset detailed biosecurity practices employed on 218 commercial swine farms across Canada in 2010. The second dataset detailed animal health status and disease occurrence on 90 of those farms between 2010 and 2012. We used expert judgement to identify 15 biosecurity practices that were considered the most important in mitigating disease occurrence on farms. These included: proximity to other livestock holdings, the health status of purchased stock, manure disposal methods, as well as the procedures for admitting vehicles and staff. Four diseases were included in the BBN: Porcine reproductive and respiratory syndrome (PRRS), (a prevalent endemic aerosol pathogen), Swine influenza (SI) (a viral respiratory aerosol pathogen), Mycoplasma pneumonia (MP) (an endemic respiratory disease spread by close contact and aerosol) and Swine dysentery (SD) (an enteric disease which is re-emerging in North America). This model indicated that the probability of disease occurrence was influenced by a number of manageable biosecurity practices. Increased probability of PRRS and of MP were associated with spilt feed (feed that did not fall directly in a feeding trough), not being disposed of immediately and with manure being brought onto the farm premises and spread on land adjacent to the pigs. Increased probabilities of SI

  14. Exploring the role of voluntary disease schemes on UK farmer bio-security behaviours: Findings from the Norfolk-Suffolk Bovine Viral Diarrhoea control scheme.

    PubMed

    Azbel-Jackson, Lena; Heffernan, Claire; Gunn, George; Brownlie, Joe

    2018-01-01

    The article describes the influence of a disease control scheme (the Norfolk-Suffolk Bovine Viral Diarrhoea Disease (BVD) Eradication scheme) on farmers' bio-security attitudes and behaviours. In 2010, a survey of 100 cattle farmers (53 scheme members vs. 47 out of scheme farmers) was undertaken among cattle farmers residing in Norfolk and Suffolk counties in the UK. A cross-sectional independent measures design was employed. The main analytical tool was content analysis. The following variables at the farmer-level were explored: the specific BVD control measures adopted, livestock disease priorities, motivation for scheme membership, wider knowledge acquisition, biosecurity behaviours employed and training course attendance. The findings suggest that participation in the BVD scheme improved farmers' perception of the scheme benefits and participation in training courses. However, no association was found between the taking part in the BVD scheme and livestock disease priorities or motivation for scheme participation, or knowledge about BVD bio-security measures employed. Equally importantly, scheme membership did appear to influence the importance accorded specific bio-security measures. Yet such ranking did not appear to reflect the actual behaviours undertaken. As such, disease control efforts alone while necessary, are insufficient. Rather, to enhance farmer bio-security behaviours significant effort must be made to address underlying attitudes to the specific disease threat involved.

  15. Nanotechnology in global medicine and human biosecurity: private interests, policy dilemmas, and the calibration of public health law.

    PubMed

    Faunce, Thomas A

    2007-01-01

    This paper considers how best to approach dilemmas posed to global health and biosecurity policy by increasing advances in practical applications of nanotechnology. The type of nano-technology policy dilemmas discussed include: (1) expenditure of public funds, (2) public-funded research priorities, (3) public confidence in government and science and, finally, (4) public safety. The article examines the value in this context of a legal obligation that the development of relevant public health law be calibrated against less corporate-influenced norms issuing from bioethics and international human rights.

  16. Biosecurity and the management of emergency animal disease among commercial beef producers in New South Wales and Queensland (Australia).

    PubMed

    Hernández-Jover, M; Higgins, V; Bryant, M; Rast, L; McShane, C

    2016-11-01

    Australia places great importance on the prevention and management of emergency animal diseases (EAD), with strict quarantine measures offshore and at the border. Livestock producers are crucial for disease control onshore; however, limited information is available on commercial livestock producers' practices in relation to the management of disease risks. The aims of this paper are to investigate how commercial beef producers in Australia's Northern and Southern beef zones manage EADs and to identify drivers for effective biosecurity and EAD prevention. This paper forms part of a broader mixed methods research project involving an analysis of literature and current policies, qualitative semi-structured interviews with government and industry stakeholders and a cross-sectional study among beef producers. The cross-sectional study used a postal survey (n=182) and face-to-face interviews (n=34) to gather data on beef producers' knowledge and practices on biosecurity and EADs and their communication networks. Findings indicate that producers are uncertain about the roles and responsibilities of stakeholders involved in biosecurity and EAD management. This uncertainty may create confusion about EAD management and impact upon producers' willingness to report animal disease, with over 20% reporting the last veterinary contact more than five years ago and an additional 8.5% who had never contacted a veterinarian. Producers had a generally high awareness of the key sources of animal disease risk and they prioritise herd health planning as part of their everyday practices. Over 40% of producers had limited knowledge of the meaning of EAD; and EAD and biosecurity planning was given a low priority, primarily due to the perceived limited likelihood of an EAD event in Australia and the belief that EAD prevention is primarily the role of government. Only a moderate implementation of biosecurity practices, such as isolating incoming animals, having a single property entry point

  17. Synthetic biology and biosecurity: challenging the "myths".

    PubMed

    Jefferson, Catherine; Lentzos, Filippa; Marris, Claire

    2014-01-01

    Synthetic biology, a field that aims to "make biology easier to engineer," is routinely described as leading to an increase in the "dual-use" threat, i.e., the potential for the same scientific research to be "used" for peaceful purposes or "misused" for warfare or terrorism. Fears have been expressed that the "de-skilling" of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five "myths" that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these "myths" play an important role in defining synthetic biology as a "promissory" field of research and as an "emerging technology" in need of governance.

  18. Exploring the role of voluntary disease schemes on UK farmer bio-security behaviours: Findings from the Norfolk-Suffolk Bovine Viral Diarrhoea control scheme

    PubMed Central

    Azbel-Jackson, Lena; Heffernan, Claire; Gunn, George; Brownlie, Joe

    2018-01-01

    The article describes the influence of a disease control scheme (the Norfolk-Suffolk Bovine Viral Diarrhoea Disease (BVD) Eradication scheme) on farmers' bio-security attitudes and behaviours. In 2010, a survey of 100 cattle farmers (53 scheme members vs. 47 out of scheme farmers) was undertaken among cattle farmers residing in Norfolk and Suffolk counties in the UK. A cross-sectional independent measures design was employed. The main analytical tool was content analysis. The following variables at the farmer-level were explored: the specific BVD control measures adopted, livestock disease priorities, motivation for scheme membership, wider knowledge acquisition, biosecurity behaviours employed and training course attendance. The findings suggest that participation in the BVD scheme improved farmers' perception of the scheme benefits and participation in training courses. However, no association was found between the taking part in the BVD scheme and livestock disease priorities or motivation for scheme participation, or knowledge about BVD bio-security measures employed. Equally importantly, scheme membership did appear to influence the importance accorded specific bio-security measures. Yet such ranking did not appear to reflect the actual behaviours undertaken. As such, disease control efforts alone while necessary, are insufficient. Rather, to enhance farmer bio-security behaviours significant effort must be made to address underlying attitudes to the specific disease threat involved. PMID:29432435

  19. Relative associations of cattle movements, local spread, and biosecurity with bovine viral diarrhoea virus (BVDV) seropositivity in beef and dairy herds.

    PubMed

    Gates, M C; Woolhouse, M E J; Gunn, G J; Humphry, R W

    2013-11-01

    The success of bovine viral diarrhoea virus (BVDV) eradication campaigns can be undermined by spread through local transmission pathways and poor farmer compliance with biosecurity recommendations. This work combines recent survey data with cattle movement data to explore the issues likely to impact on the success of BVDV control in Scotland. In this analysis, data from 249 beef suckler herds and 185 dairy herds in Scotland were studied retrospectively to determine the relative influence of cattle movements, local spread, and biosecurity on BVDV seropositivity. Multivariable logistic regression models revealed that cattle movement risk factors had approximately 3 times greater explanatory power than risk factors for local spread amongst beef suckler herds, but approximately the same explanatory power as risk factors for local spread amongst dairy herds. These findings are most likely related to differences in cattle husbandry practices and suggest that where financial prioritization is required, focusing on reducing movement-based risk is likely to be of greatest benefit when applied to beef suckler herds. The reported use of biosecurity measures such as purchasing cattle from BVDV accredited herds only, performing diagnostic screening at the time of sale, implementing isolation periods for purchased cattle, and installing double fencing on shared field boundaries had minimal impact on the risk of beef or dairy herds being seropositive for BVDV. Only 28% of beef farmers and 24% of dairy farmers with seropositive herds recognized that their cattle were affected by BVDV and those that did perceive a problem were no less likely to sell animals as replacement breeding stock and no more likely to implement biosecurity measures against local spread than farmers with no perceived problems. In relation to the current legislative framework for BVDV control in Scotland, these findings emphasize the importance of requiring infected herds take appropriate biosecurity measures

  20. Challenges and Practices in Building and Implementing Biosafety and Biosecurity Programs to Enable Basic and Translational Research with Select Agents.

    PubMed

    Jonsson, Colleen B; Cole, Kelly Stefano; Roy, Chad J; Perlin, David S; Byrne, Gerald

    2013-04-29

    Select agent research in the United States must meet federally-mandated biological surety guidelines and rules which are comprised of two main components: biosecurity and biosafety. Biosecurity is the process employed for ensuring biological agents are properly safeguarded against theft, loss, diversion, unauthorized access or use/release. Biosafety is those processes that ensure that operations with such agents are conducted in a safe, secure and reliable manner. As such, a biological surety program is generally concerned with biological agents that present high risk for adverse medical and/or agricultural consequences upon release outside of proper containment. The U.S. Regional and National Biocontainment Laboratories (RBL, NBL) represent expertise in this type of research, and are actively engaged in the development of programs to address these critical needs and federal requirements. While this comprises an ongoing activity for the RBLs, NBLs and other facilities that handle select agents as new guidelines and regulations are implemented, the present article is written with the goal of presenting a simplified yet comprehensive review of these requirements. Herein, we discuss the requirements and the various activities that the RBL/NBL programs have implemented to achieve these metrics set forth by various agencies within the U.S. Federal government.

  1. Challenges and Practices in Building and Implementing Biosafety and Biosecurity Programs to Enable Basic and Translational Research with Select Agents

    PubMed Central

    Jonsson, Colleen B.; Cole, Kelly Stefano; Roy, Chad J.; Perlin, David S.; Byrne, Gerald

    2014-01-01

    Select agent research in the United States must meet federally-mandated biological surety guidelines and rules which are comprised of two main components: biosecurity and biosafety. Biosecurity is the process employed for ensuring biological agents are properly safeguarded against theft, loss, diversion, unauthorized access or use/release. Biosafety is those processes that ensure that operations with such agents are conducted in a safe, secure and reliable manner. As such, a biological surety program is generally concerned with biological agents that present high risk for adverse medical and/or agricultural consequences upon release outside of proper containment. The U.S. Regional and National Biocontainment Laboratories (RBL, NBL) represent expertise in this type of research, and are actively engaged in the development of programs to address these critical needs and federal requirements. While this comprises an ongoing activity for the RBLs, NBLs and other facilities that handle select agents as new guidelines and regulations are implemented, the present article is written with the goal of presenting a simplified yet comprehensive review of these requirements. Herein, we discuss the requirements and the various activities that the RBL/NBL programs have implemented to achieve these metrics set forth by various agencies within the U.S. Federal government. PMID:24900945

  2. Effect of enhanced biosecurity and selected on-farm factors on Campylobacter colonization of chicken broilers.

    PubMed

    Georgiev, M; Beauvais, W; Guitian, J

    2017-02-01

    Human campylobacteriosis is the most commonly reported gastrointestinal bacterial infection in the EU; poultry meat has been identified as the main source of infection. We tested the hypothesis that enhanced biosecurity and other factors such as welfare status, breed, the practice of partial depopulation and number of empty days between flocks may prevent Campylobacter spp. caecal colonization of poultry batches at high levels (>123 000 c.f.u./g in pooled caecal samples). We analysed data from 2314 poultry batches sampled at slaughter in the UK in 2011-2013. We employed random-effects logistic regression to account for clustering of batches within farms and adjust for confounding. We estimated population attributable fractions using adjusted risk ratios. Enhanced biosecurity reduced the odds of colonization at partial depopulation [odds ratio (OR) 0·25, 95% confidence interval (CI) 0·14-0·47] and, to a lesser extent, at final depopulation (OR 0·47, 95% CI 0·25-0·89). An effect of the type of breed was also found. Under our assumptions, approximately 1/3 of highly colonized batches would be avoided if they were all raised under enhanced biosecurity or without partial depopulation. The results of the study indicate that on-farm measures can play an important role in reducing colonization of broiler chickens with Campylobacter spp. and as a result human exposure.

  3. Comparative Evaluation of Biological Performance, Biosecurity, and Availability of Cellulose-Based Absorbable Hemostats.

    PubMed

    Wu, Yadong; Wang, Fang; Huang, Yudong

    2018-05-01

    Hemorrhage remains a leading cause of death after trauma, and developing a hemostat with excellent performance and good biosecurity is an extremely active area of research and commercial product development. Although oxidized regenerated cellulose (ORC) has been developed to address these problems, it is not always efficient and its biosecurity is not perfect. We aimed to refine ORC via a simple and mild neutralization method. The prepared neutralized oxidized regenerated cellulose (NORC) showed a superior gel property due to its chemical structure. The biological performance of both ORC and NORC was systematically evaluated; the results showed that ORC would induce erythema and edema in the irritation test, whereas NORC did not cause any adverse inflammation, indicating NORC had desirable biocompatibility. We further demonstrated that NORC confirmed to the toxicity requirements of International Organization for Standardization (ISO) standards; however, ORC showed an unacceptable cytotoxicity. The rabbit hepatic defect model stated that NORC exhibited better ability of hemostasis, which was attributed to its significant gel performance in physiological environment.

  4. Associations Between the Level of Biosecurity and Occurrence of Dermanyssus gallinae and Salmonella spp. in Layer Farms.

    PubMed

    Sylejmani, Driton; Musliu, Arben; Ramadani, Naser; Sparagano, Olivier; Hamidi, Afrim

    2016-06-01

    Salmonella and the poultry red mite (Dermanyssus gallinae) remain very challenging diseases for the poultry industry worldwide because of the inefficiency of implementing and integrating eradication and control programs, which results in very high economic losses to the poultry industry. The aim of this study was to determine the association between biosecurity levels in layer farms and the occurrence of both D. gallinae and Salmonella spp., as well as the relationship between D. gallinae infestations on farms and Salmonella occurrence. For this purpose, 22 layer farms using the common battery cage housing system in different parts of Kosovo were randomly selected and analyzed for the presence of D. gallinae and Salmonella in samples, such as feces, water, feed, and dust. Two pooled samples of D. gallinae (2n = 100) were directly analyzed for the presence of Salmonella in the outer and inner parts of cuticula from D. gallinae. A chi-square test was used to determine the association between experience in poultry production, rearing, and level of different biosecurity elements in relation to the occurrence of D. gallinae and Salmonella. Dermanyssus gallinae was found on 15 farms, whereas Salmonella was found on eight of those 15 farms from different environmental samples and on one farm where D. gallinae was not found. In two pooled samples Salmonella was isolated directly from the inner part of the cuticula from D. gallinae, which represents the first direct isolation of Salmonella from D. gallinae mites. Association between the level of biosecurity and the occurrence of D. gallinae and Salmonella was strong. The study indicates that proper biosecurity measures should be in place to lower the occurrence of D. gallinae and Salmonella.

  5. Threat of invasive pests from within national borders.

    PubMed

    Paini, Dean R; Worner, Susan P; Cook, David C; De Barro, Paul J; Thomas, Matthew B

    2010-11-16

    Predicting and ranking potential invasive species present significant challenges to researchers and biosecurity agencies. Here we analyse a worldwide database of pest species assemblages to generate lists of the top 100 insect pests most likely to establish in the United States and each of its 48 contiguous states. For the United States as a whole, all of the top 100 pest species have already established. Individual states however tend to have many more 'gaps' with most states having at least 20 species absent from their top 100 list. For all but one state, every exotic pest species currently absent from a state's top 100 can be found elsewhere in the contiguous United States. We conclude that the immediate threat from known invasive insect pests is greater from within the United States than without. Our findings have potentially significant implications for biosecurity policy, emphasizing the need to consider biosecurity measures beyond established national border interventions.

  6. Barcoding and Border Biosecurity: Identifying Cyprinid Fishes in the Aquarium Trade

    PubMed Central

    Collins, Rupert A.; Armstrong, Karen F.; Meier, Rudolf; Yi, Youguang; Brown, Samuel D. J.; Cruickshank, Robert H.; Keeling, Suzanne; Johnston, Colin

    2012-01-01

    Background Poorly regulated international trade in ornamental fishes poses risks to both biodiversity and economic activity via invasive alien species and exotic pathogens. Border security officials need robust tools to confirm identifications, often requiring hard-to-obtain taxonomic literature and expertise. DNA barcoding offers a potentially attractive tool for quarantine inspection, but has yet to be scrutinised for aquarium fishes. Here, we present a barcoding approach for ornamental cyprinid fishes by: (1) expanding current barcode reference libraries; (2) assessing barcode congruence with morphological identifications under numerous scenarios (e.g. inclusion of GenBank data, presence of singleton species, choice of analytical method); and (3) providing supplementary information to identify difficult species. Methodology/Principal Findings We sampled 172 ornamental cyprinid fish species from the international trade, and provide data for 91 species currently unrepresented in reference libraries (GenBank/Bold). DNA barcodes were found to be highly congruent with our morphological assignments, achieving success rates of 90–99%, depending on the method used (neighbour-joining monophyly, bootstrap, nearest neighbour, GMYC, percent threshold). Inclusion of data from GenBank (additional 157 spp.) resulted in a more comprehensive library, but at a cost to success rate due to the increased number of singleton species. In addition to DNA barcodes, our study also provides supporting data in the form of specimen images, morphological characters, taxonomic bibliography, preserved vouchers, and nuclear rhodopsin sequences. Using this nuclear rhodopsin data we also uncovered evidence of interspecific hybridisation, and highlighted unrecognised diversity within popular aquarium species, including the endangered Indian barb Puntius denisonii. Conclusions/Significance We demonstrate that DNA barcoding provides a highly effective biosecurity tool for rapidly identifying

  7. A cross-sectional study on biosecurity practices and communication networks of poultry exhibition in Australia.

    PubMed

    Hernández-Jover, Marta; Schemann, Kathrin; Toribio, Jenny-Ann L M L

    2013-07-01

    Poultry exhibitors are perceived to pose a biosecurity risk due to the high frequency of movements of birds and the close contact between birds at poultry shows. This cross-sectional study assessed the risks posed by poultry exhibitors in Australia using face-to-face interviews (n=46) at eight poultry shows and a postal survey. Univariable and multivariable logistic regression analyses were used to investigate associations between age, sex, location, number of birds, number of shows attended per year and distance travelled to a show, with biosecurity and communication practices. A total of 357 (29.1%) exhibitors responded to the postal survey. Among all participants (n=403), most had owned poultry for more than 15 years (71.9%), kept less than 200 birds (83.4%), mainly chicken (96.7%) and waterfowl (17.8%), and reported not having any commercial poultry operation within 5 km of their property (85.4%). Despite most exhibitors (90.8%) having at least some knowledge of biosecurity principles; some of their practices could pose a risk for disease introduction and spread. Most exhibitors kept their birds with outdoor access (87.0%) and 67.0% of exhibitors reported contact of wild birds with domestic birds being possible. Only 60% and 40.6% of exhibitors cleaned transport cages after each use and isolated birds for over two weeks, respectively, with men and exhibitors keeping more birds less likely (P=0.003) to conduct this practice. Most exhibitors (75.0%) attended more than 5 shows per year, travelling long distances (up to 1000 km) to attend a show. Although most exhibitors would source and sell their birds from and to other exhibitors and at poultry shows, some reported sourcing (15.2%) and selling (25.3%) their birds at live bird markets. In addition, contact with veterinarians was low (23.1%), with younger exhibitors and women more likely to contact a veterinarian than older exhibitors (P=0.006) and men (P=0.017). Other poultry exhibitors were reported as the most

  8. Synthetic Biology and Biosecurity: Challenging the “Myths”

    PubMed Central

    Jefferson, Catherine; Lentzos, Filippa; Marris, Claire

    2014-01-01

    Synthetic biology, a field that aims to “make biology easier to engineer,” is routinely described as leading to an increase in the “dual-use” threat, i.e., the potential for the same scientific research to be “used” for peaceful purposes or “misused” for warfare or terrorism. Fears have been expressed that the “de-skilling” of biology, combined with online access to the genomic DNA sequences of pathogenic organisms and the reduction in price for DNA synthesis, will make biology increasingly accessible to people operating outside well-equipped professional research laboratories, including people with malevolent intentions. The emergence of do-it-yourself (DIY) biology communities and of the student iGEM competition has come to epitomize this supposed trend toward greater ease of access and the associated potential threat from rogue actors. In this article, we identify five “myths” that permeate discussions about synthetic biology and biosecurity, and argue that they embody misleading assumptions about both synthetic biology and bioterrorism. We demonstrate how these myths are challenged by more realistic understandings of the scientific research currently being conducted in both professional and DIY laboratories, and by an analysis of historical cases of bioterrorism. We show that the importance of tacit knowledge is commonly overlooked in the dominant narrative: the focus is on access to biological materials and digital information, rather than on human practices and institutional dimensions. As a result, public discourse on synthetic biology and biosecurity tends to portray speculative scenarios about the future as realities in the present or the near future, when this is not warranted. We suggest that these “myths” play an important role in defining synthetic biology as a “promissory” field of research and as an “emerging technology” in need of governance. PMID:25191649

  9. The impact of biosecurity and partial depopulation on Campylobacter prevalence in Irish broiler flocks with differing levels of hygiene and economic performance

    PubMed Central

    Smith, Shaun; Messam, Locksley L. McV.; Meade, Joseph; Gibbons, James; McGill, Kevina; Bolton, Declan; Whyte, Paul

    2016-01-01

    Background Campylobacter jejuni is the leading bacterial food-borne pathogen within the European Union (EU), and poultry meat is the primary route for transmission to humans. Material and methods This study examined the impact of partial depopulation (thinning), season, and farm performance (economic, hygiene, and biosecurity) on Campylobacter prevalence in Irish broilers over a 13-month period. Ten caecal samples were taken per flock, for a total of 211 flocks from 23 farms during the duration of the study. Campylobacter was isolated and enumerated according to modified published ISO methods for veterinary samples. Biosecurity was evaluated through a questionnaire based on risk factors for Campylobacter identified in previous studies. Hygiene compliance was assessed from audit records taken over the course of 1 year. All information relating to biosecurity and hygiene was obtained directly from the processing company. This was done to ensure farmers were unaware they were being monitored for Campylobacter prevalence and prevent changes to their behaviour. Results and discussion Farms with high performance were found to have significantly lower Campylobacter prevalence at first depopulation compared with low-performance farms across all seasons (P≤0.01). Peak Campylobacter levels were observed during the summer season at first thin in both the high- and low-performance groups. Campylobacter prevalence was found to increase to ≥85% in both high- and low-performance farms across all seasons at final depopulation, suggesting that Campylobacter was introduced during the first depopulation. On low-performance farms, four biosecurity interventions were found to significantly reduce the odds of a flock being Campylobacter positive (physical step-over barrier OR=0.17, house-specific footwear OR=0.13, absence of water body within 0.5 km OR=0.13, two or more broiler houses on a farm OR=0.16), compared with farms without these interventions. For high-performance farms, no

  10. The impact of biosecurity and partial depopulation on Campylobacter prevalence in Irish broiler flocks with differing levels of hygiene and economic performance.

    PubMed

    Smith, Shaun; Messam, Locksley L McV; Meade, Joseph; Gibbons, James; McGill, Kevina; Bolton, Declan; Whyte, Paul

    2016-01-01

    Campylobacter jejuni is the leading bacterial food-borne pathogen within the European Union (EU), and poultry meat is the primary route for transmission to humans. This study examined the impact of partial depopulation (thinning), season, and farm performance (economic, hygiene, and biosecurity) on Campylobacter prevalence in Irish broilers over a 13-month period. Ten caecal samples were taken per flock, for a total of 211 flocks from 23 farms during the duration of the study. Campylobacter was isolated and enumerated according to modified published ISO methods for veterinary samples. Biosecurity was evaluated through a questionnaire based on risk factors for Campylobacter identified in previous studies. Hygiene compliance was assessed from audit records taken over the course of 1 year. All information relating to biosecurity and hygiene was obtained directly from the processing company. This was done to ensure farmers were unaware they were being monitored for Campylobacter prevalence and prevent changes to their behaviour. Farms with high performance were found to have significantly lower Campylobacter prevalence at first depopulation compared with low-performance farms across all seasons (P≤0.01). Peak Campylobacter levels were observed during the summer season at first thin in both the high- and low-performance groups. Campylobacter prevalence was found to increase to ≥85% in both high- and low-performance farms across all seasons at final depopulation, suggesting that Campylobacter was introduced during the first depopulation. On low-performance farms, four biosecurity interventions were found to significantly reduce the odds of a flock being Campylobacter positive (physical step-over barrier OR=0.17, house-specific footwear OR=0.13, absence of water body within 0.5 km OR=0.13, two or more broiler houses on a farm OR=0.16), compared with farms without these interventions. For high-performance farms, no single biosecurity intervention was identified as

  11. Compatibility between livestock databases used for quantitative biosecurity response in New Zealand.

    PubMed

    Jewell, C P; van Andel, M; Vink, W D; McFadden, A M J

    2016-05-01

    To characterise New Zealand's livestock biosecurity databases, and investigate their compatibility and capacity to provide a single integrated data source for quantitative outbreak analysis. Contemporary snapshots of the data in three national livestock biosecurity databases, AgriBase, FarmsOnLine (FOL) and the National Animal Identification and Tracing Scheme (NAIT), were obtained on 16 September, 1 September and 30 April 2014, respectively, and loaded into a relational database. A frequency table of animal numbers per farm was calculated for the AgriBase and FOL datasets. A two dimensional kernel density estimate was calculated for farms reporting the presence of cattle, pigs, deer, and small ruminants in each database and the ratio of farm densities for AgriBase versus FOL calculated. The extent to which records in the three databases could be matched and linked was quantified, and the level of agreement amongst them for the presence of different species on properties assessed using Cohen's kappa statistic. AgriBase contained fewer records than FOL, but recorded animal numbers present on each farm, whereas FOL contained more records, but captured only presence/absence of animals. The ratio of farm densities in AgriBase relative to FOL for pigs and deer was reasonably homogeneous across New Zealand, with AgriBase having a farm density approximately 80% of FOL. For cattle and small ruminants, there was considerable heterogeneity, with AgriBase showing a density of cattle farms in the Central Otago region that was 20% of FOL, and a density of small ruminant farms in the central West Coast area that was twice that of FOL. Only 37% of records in FOL could be linked to AgriBase, but the level of agreement for the presence of different species between these databases was substantial (kappa>0.6). Both NAIT and FOL shared common farm identifiers which could be used to georeference animal movements, and there was a fair to substantial agreement (kappa 0.32-0.69) between

  12. A survey of Asian life scientists :the state of biosciences, laboratory biosecurity, and biosafety in Asia.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gaudioso, Jennifer Marie

    2006-02-01

    Over 300 Asian life scientists were surveyed to provide insight into work with infectious agents. This report provides the reader with a more complete understanding of the current practices employed to study infectious agents by laboratories located in Asian countries--segmented by level of biotechnology sophistication. The respondents have a variety of research objectives and study over 60 different pathogens and toxins. Many of the respondents indicated that their work was hampered by lack of adequate resources and the difficulty of accessing critical resources. The survey results also demonstrate that there appears to be better awareness of laboratory biosafety issues comparedmore » to laboratory biosecurity. Perhaps not surprisingly, many of these researchers work with pathogens and toxins under less stringent laboratory biosafety and biosecurity conditions than would be typical for laboratories in the West.« less

  13. Implementation of a Personnel Reliability Program as a Facilitator of Biosafety and Biosecurity Culture in BSL-3 and BSL-4 Laboratories

    PubMed Central

    Weaver, Patrick; Fitch, J. Patrick; Johnson, Barbara; Pearl, R. Marene

    2013-01-01

    In late 2010, the National Biodefense Analysis and Countermeasures Center (NBACC) implemented a Personnel Reliability Program (PRP) with the goal of enabling active participation by its staff to drive and improve the biosafety and biosecurity culture at the organization. A philosophical keystone for accomplishment of NBACC's scientific mission is simultaneous excellence in operations and outreach. Its personnel reliability program builds on this approach to: (1) enable and support a culture of responsibility based on human performance principles, (2) maintain compliance with regulations, and (3) address the risk associated with the insider threat. Recently, the Code of Federal Regulations (CFR) governing use and possession of biological select agents and toxins (BSAT) was amended to require a pre-access suitability assessment and ongoing evaluation for staff accessing Tier 1 BSAT. These 2 new requirements are in addition to the already required Federal Bureau of Investigation (FBI) Security Risk Assessment (SRA). Two years prior to the release of these guidelines, NBACC developed its PRP to supplement the SRA requirement as a means to empower personnel and foster an operational environment where any and all work with BSAT is conducted in a safe, secure, and reliable manner. PMID:23745523

  14. Implementation of a personnel reliability program as a facilitator of biosafety and biosecurity culture in BSL-3 and BSL-4 laboratories.

    PubMed

    Higgins, Jacki J; Weaver, Patrick; Fitch, J Patrick; Johnson, Barbara; Pearl, R Marene

    2013-06-01

    In late 2010, the National Biodefense Analysis and Countermeasures Center (NBACC) implemented a Personnel Reliability Program (PRP) with the goal of enabling active participation by its staff to drive and improve the biosafety and biosecurity culture at the organization. A philosophical keystone for accomplishment of NBACC's scientific mission is simultaneous excellence in operations and outreach. Its personnel reliability program builds on this approach to: (1) enable and support a culture of responsibility based on human performance principles, (2) maintain compliance with regulations, and (3) address the risk associated with the insider threat. Recently, the Code of Federal Regulations (CFR) governing use and possession of biological select agents and toxins (BSAT) was amended to require a pre-access suitability assessment and ongoing evaluation for staff accessing Tier 1 BSAT. These 2 new requirements are in addition to the already required Federal Bureau of Investigation (FBI) Security Risk Assessment (SRA). Two years prior to the release of these guidelines, NBACC developed its PRP to supplement the SRA requirement as a means to empower personnel and foster an operational environment where any and all work with BSAT is conducted in a safe, secure, and reliable manner.

  15. Compliance/non-compliance with biosecurity rules specified in the Danish Quality Assurance system (KIK) and Campylobacter-positive broiler flocks 2012 and 2013.

    PubMed

    Sandberg, M; Dahl, J; Lindegaard, L L; Pedersen, J R

    2017-01-01

    One source for Campylobacter jejuni infections in humans could be consumption of broiler meat. Transmission of Campylobacter into broiler houses/flocks occurs via many routes. A number of biosecurity rules is specified in the Quality Assurance System in Danish Chicken Production (KIK) - for which the broiler producers annually are audited for compliance with, by bureau Veritas. Multivariable logistic regression models were used to investigated the association between Compliance/non-compliance with biosecurity rules and Campylobacter-positive flocks - on KIK data from 2012 and 2013. Month and before after audit period were also included in the models. KIK rules important to comply with were: no vegetation around houses, closed systems for feed storage and distribution, and division between clean and unclean zones within broiler houses. A Campylobacter-reducing effect was observed of audit visits (in itself), indicating that there is more focus on compliance with KIK at the time of an audit visit, and that adequate daily biosecurity behavior is important. © 2016 Poultry Science Association Inc.

  16. Indirect Transmission of Influenza A Virus between Pig Populations under Two Different Biosecurity Settings

    PubMed Central

    Allerson, Matt W.; Cardona, Carol J.; Torremorell, Montserrat

    2013-01-01

    Respiratory disease due to influenza virus is common in both human and swine populations around the world with multiple transmission routes capable of transmitting influenza virus, including indirect routes. The objective of this study was to evaluate the role of fomites in influenza A virus (IAV) transmission between pig populations separated by two different biosecurity settings. Thirty-five pigs were divided into four experimental groups: 10 pigs (1 replicate) were assigned to the infected group (I), 10 pigs (2 replicates of 5 pigs) were assigned to the low biosecurity sentinel group (LB), 10 pigs (2 replicates of 5 pigs) were assigned to the medium biosecurity sentinel group (MB), and 5 pigs (1 replicate) were assigned to the negative control group (NC). Eight of 10 pigs in the infected group were inoculated with IAV and 36 hours following inoculation, personnel movement events took place in order to move potentially infectious clothing and personal protective equipment (PPE) to sentinel pig rooms. Following contact with the infected group, personnel moved to the MB group after designated hygiene measures while personnel moved directly to the LB group. Nasal swabs and blood samples were collected from pigs to assess IAV infection status and fomites were sampled and tested via RRT-PCR. All experimentally inoculated pigs were infected with IAV and 11 of the 144 fomite samples collected following contact with infected pigs were low level positive for IAV genome. One replicate of each sentinel groups LB and MB became infected with IAV and all five pigs were infected over time. This study provides evidence that fomites can serve as an IAV transmission route from infected to sentinel pigs and highlights the need to focus on indirect routes as well as direct routes of transmission for IAV. PMID:23805306

  17. Houston biosecurity: building a national model.

    PubMed Central

    Casscells, Ward; Mirhaji, Parsa; Lillibridge, Scott; Madjid, Mohammad

    2004-01-01

    On September 11, 2001, Al Qaeda terrorists committed an atrocity when they used domestic jetliners to crash into buildings in New York City and Washington, DC, killing thousands of people. In October 2001, another act of savagery occurred, this time using anthrax, not airplanes, to take innocent lives. Each incident demonstrates the vulnerability of an open society, and Americans are left to wonder how such acts can be prevented. Two years later, Al Qaeda operatives are reportedly regrouping, recruiting, and changing their tactics to distribute money and messages to operatives around the world. Many experts believe that terrorist attacks are inevitable. Every city is vulnerable to an attack, and none are fully prepared to handle the residual impact of a biological or chemical attack. A survey conducted by the Cable News Network (CNN) in January 2002, studied 30 major US cities, ranking them based on 6 statistical indices of vulnerability. Thirteen cities were deemed better prepared than Houston, 10 were in a similar state of preparedness, and only 6 were less prepared than Houston. We will discuss the protective measures that have been put in place in Houston, and future steps to take. Other cities can model Houston's experience to develop similar plans nation-wide. PMID:17060983

  18. Houston biosecurity: building a national model.

    PubMed

    Casscells, Ward; Mirhaji, Parsa; Lillibridge, Scott; Madjid, Mohammad

    2004-01-01

    On September 11, 2001, Al Qaeda terrorists committed an atrocity when they used domestic jetliners to crash into buildings in New York City and Washington, DC, killing thousands of people. In October 2001, another act of savagery occurred, this time using anthrax, not airplanes, to take innocent lives. Each incident demonstrates the vulnerability of an open society, and Americans are left to wonder how such acts can be prevented. Two years later, Al Qaeda operatives are reportedly regrouping, recruiting, and changing their tactics to distribute money and messages to operatives around the world. Many experts believe that terrorist attacks are inevitable. Every city is vulnerable to an attack, and none are fully prepared to handle the residual impact of a biological or chemical attack. A survey conducted by the Cable News Network (CNN) in January 2002, studied 30 major US cities, ranking them based on 6 statistical indices of vulnerability. Thirteen cities were deemed better prepared than Houston, 10 were in a similar state of preparedness, and only 6 were less prepared than Houston. We will discuss the protective measures that have been put in place in Houston, and future steps to take. Other cities can model Houston's experience to develop similar plans nation-wide.

  19. The dual use of research ethics committees: why professional self-governance falls short in preserving biosecurity.

    PubMed

    Salloch, Sabine

    2018-06-05

    Dual Use Research of Concern (DURC) constitutes a major challenge for research practice and oversight on the local, national and international level. The situation in Germany is shaped by two partly competing suggestions of how to regulate security-related research: The German Ethics Council, as an independent political advisory body, recommended a series of measures, including national legislation on DURC. Competing with that, the German National Academy of Sciences and the German Research Foundation, as two major professional bodies, presented a strategy which draws on the self-control of science and, inter alia, suggests expanding the scope of research ethics committees (RECs) to an evaluation of DURC. This situation is taken as an occasion to further discuss the scope and limits of professional self-control with respect to security-related research. The role of RECs as professional bodies of science is particularly analyzed, referring to the theoretical backgrounds of professionalism. Two key sociological features of professionalism - ethical orientation and professional self-control - are discussed with respect to the practice of biomedical science. Both attributes are then analyzed with respect to the assessment of DURC by RECs. In conclusion, it is stated that issues of biosecurity transcend the boundaries of the scientific community and that a more comprehensive strategy should be implemented encompassing both professional self-control and legal oversight.

  20. 3 CFR 13486 - Executive Order 13486 of January 9, 2009. Strengthening Laboratory Biosecurity in the United States

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... agents and toxins. Sec. 2. Establishment and Operation of the Working Group. (a) There is hereby established, within the Department of Defense for administrative purposes only, the Working Group on Strengthening the Biosecurity of the United States (Working Group). (b) The Working Group shall consist...

  1. Code of Conduct on Biosecurity for Biological Resource Centres: procedural implementation.

    PubMed

    Rohde, Christine; Smith, David; Martin, Dunja; Fritze, Dagmar; Stalpers, Joost

    2013-07-01

    A globally applicable code of conduct specifically dedicated to biosecurity has been developed together with guidance for its procedural implementation. This is to address the regulations governing potential dual-use of biological materials, associated information and technologies, and reduce the potential for their malicious use. Scientists researching and exchanging micro-organisms have a responsibility to prevent misuse of the inherently dangerous ones, that is, those possessing characters such as pathogenicity or toxin production. The code of conduct presented here is based on best practice principles for scientists and their institutions working with biological resources with a specific focus on micro-organisms. It aims to raise awareness of regulatory needs and to protect researchers, their facilities and stakeholders. It reflects global activities in this area in response to legislation such as that in the USA, the PATRIOT Act of 2001, Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism Act of 2001; the Anti-Terrorism Crime and Security Act 2001 and subsequent amendments in the UK; the EU Dual-Use Regulation; and the recommendations of the Organization for Economic Co-operation and Development (OECD), under their Biological Resource Centre (BRC) Initiative at the beginning of the millennium (OECD, 2001). Two project consortia with international partners came together with experts in the field to draw up a Code of Conduct on Biosecurity for BRCs to ensure that culture collections and microbiologists in general worked in a way that met the requirements of such legislation. A BRC is the modern day culture collection that adds value to its holdings and implements common best practice in the collection and supply of strains for research and development. This code of conduct specifically addresses the work of public service culture collections and describes the issues of importance and the controls or

  2. Diseases of livestock in the Pacific Islands region: setting priorities for food animal biosecurity.

    PubMed

    Brioudes, Aurélie; Warner, Jeffrey; Hedlefs, Robert; Gummow, Bruce

    2015-03-01

    Most Pacific Island countries and territories (PICTs) have developing economies and face a critical shortage of veterinarians with limited financial resources allocated to their animal disease surveillance programmes. Thus, animal health authorities have to set priorities for better focusing their scarce resources. The main objective of this study was to identify animal diseases perceived to be of importance by decision makers within selected PICTs, at the regional and national levels, to ensure better targeting of animal health resources. A second objective was to investigate whether the targeted surveillance programmes resulting from this rationalized approach would also benefit the local communities engaged in livestock production. A multi-criteria prioritization process was developed, involving local experts, to score and rank 132 animal diseases based on their priority at the regional and national levels for four PICTs: Fiji, Papua New Guinea, Solomon Islands, and Vanuatu, which form part of a regional Food Animal Biosecurity Network. In parallel interviews with farmers and field animal health and production workers were conducted to assess their perception of animal diseases. The list of the top-twenty ranked diseases for the Pacific Islands region shows a mix of endemic zoonotic diseases (such as leptospirosis ranked first; brucellosis third; tuberculosis sixth; and endoparasites and ectoparasites, respectively eleventh and thirteenth) with exotic diseases (such as HPAI ranked second, FMD fifth, and rabies ninth). There were different disease ranking lists for each of the four targeted PICTs, confirming different strategies of disease prevention and control may be required for each country, rather than a regional approach. Interviewed animal health and production workers were unfamiliar with most of the prioritized diseases and a majority acknowledged that they would not be able to recognize clinical signs if outbreaks were to occur in their area

  3. It takes a combination of biosecurity, testing, and vaccination to keep bovine viral diarrhea (BVD) under control

    USDA-ARS?s Scientific Manuscript database

    This is the third installment of a 3 part series on bovine viral diarrhea (BVD), written for a lay publication whose core audience in dairy producers. Control of BVD in any dairy operation must rely on the implementation of an organized strategy combining biosecurity, surveillance and increased herd...

  4. Epidemiology of avian influenza in wild aquatic birds in a biosecurity hotspot, North Queensland, Australia.

    PubMed

    Hoque, Md Ahasanul; Burgess, Graham William; Cheam, Ai Lee; Skerratt, Lee Francis

    2015-01-01

    Migratory birds may introduce highly pathogenic H5N1 avian influenza from Southeast Asia into Australia via North Queensland, a key stopover along the East Asian-Australasian Flyway, with severe consequences for trade and human health. A 3-year repeated cross sectional study on the epidemiology of avian influenza in Australian nomadic wild aquatic birds was conducted in this potential biosecurity hotspot using molecular and serological techniques. Avian influenza virus subtypes H6 and H9 were commonly present in the studied population. It is likely that one of the H6 viruses was newly introduced through migratory birds confirming the perceived biosecurity risk. The matrix gene of another H6 virus was similar to the Australian H7 subtypes, which suggests the reassortment of a previously introduced H6 and local viruses. Similarly, a H9 subtype had a matrix gene similar to that found in Asian H9 viruses suggesting reassortment of viruses originated from Australia and Asia. Whilst H5N1 was not found, the serological study demonstrated a constant circulation of the H5 subtype in the sampled birds. The odds of being reactive for avian influenza viral antibodies were 13.1(95% CI: 5.9-28.9) for Pacific Black Ducks over Plumed Whistling Ducks, highlighting that some species of waterfowl pose a greater biosecurity risk. Antibody titres were slightly higher during warm wet compared with warm dry weather. Routine surveillance programmes should be established to monitor the introduction of avian influenza viruses from Asia and the interactions of the introduced viruses with resident viruses in order to better detect emerging pathogens in aquatic birds of North Queensland. Surveillance should be targeted towards highly susceptible species such as the Pacific Black Duck and carried out during favourable environmental conditions for viral transmission such as the wet season in northern Australia. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Analysis of the Spatial Organization of Pastures as a Contact Network, Implications for Potential Disease Spread and Biosecurity in Livestock, France, 2010.

    PubMed

    Palisson, Aurore; Courcoul, Aurélie; Durand, Benoit

    2017-01-01

    The use of pastures is part of common herd management practices for livestock animals, but contagion between animals located on neighbouring pastures is one of the major modes of infectious disease transmission between herds. At the population level, this transmission is strongly constrained by the spatial organization of pastures. The aim of this study was to answer two questions: (i) is the spatial configuration of pastures favourable to the spread of infectious diseases in France? (ii) would biosecurity measures allow decreasing this vulnerability? Based on GIS data, the spatial organization of pastures was represented using networks. Nodes were the 3,159,787 pastures reported in 2010 by the French breeders to claim the Common Agricultural Policy subsidies. Links connected pastures when the distance between them was below a predefined threshold. Premises networks were obtained by aggregating into a single node all the pastures under the same ownership. Although the pastures network was very fragmented when the distance threshold was short (1.5 meters, relevant for a directly-transmitted disease), it was not the case when the distance threshold was larger (500 m, relevant for a vector-borne disease: 97% of the nodes in the largest connected component). The premises network was highly connected as the largest connected component always included more than 83% of the nodes, whatever the distance threshold. Percolation analyses were performed to model the population-level efficacy of biosecurity measures. Percolation thresholds varied according to the modelled biosecurity measures and to the distance threshold. They were globally high (e.g. >17% of nodes had to be removed, mimicking the confinement of animals inside farm buildings, to obtain the disappearance of the large connected component). The network of pastures thus appeared vulnerable to the spread of diseases in France. Only a large acceptance of biosecurity measures by breeders would allow reducing this

  6. Analysis of the Spatial Organization of Pastures as a Contact Network, Implications for Potential Disease Spread and Biosecurity in Livestock, France, 2010

    PubMed Central

    Palisson, Aurore; Courcoul, Aurélie; Durand, Benoit

    2017-01-01

    The use of pastures is part of common herd management practices for livestock animals, but contagion between animals located on neighbouring pastures is one of the major modes of infectious disease transmission between herds. At the population level, this transmission is strongly constrained by the spatial organization of pastures. The aim of this study was to answer two questions: (i) is the spatial configuration of pastures favourable to the spread of infectious diseases in France? (ii) would biosecurity measures allow decreasing this vulnerability? Based on GIS data, the spatial organization of pastures was represented using networks. Nodes were the 3,159,787 pastures reported in 2010 by the French breeders to claim the Common Agricultural Policy subsidies. Links connected pastures when the distance between them was below a predefined threshold. Premises networks were obtained by aggregating into a single node all the pastures under the same ownership. Although the pastures network was very fragmented when the distance threshold was short (1.5 meters, relevant for a directly-transmitted disease), it was not the case when the distance threshold was larger (500 m, relevant for a vector-borne disease: 97% of the nodes in the largest connected component). The premises network was highly connected as the largest connected component always included more than 83% of the nodes, whatever the distance threshold. Percolation analyses were performed to model the population-level efficacy of biosecurity measures. Percolation thresholds varied according to the modelled biosecurity measures and to the distance threshold. They were globally high (e.g. >17% of nodes had to be removed, mimicking the confinement of animals inside farm buildings, to obtain the disappearance of the large connected component). The network of pastures thus appeared vulnerable to the spread of diseases in France. Only a large acceptance of biosecurity measures by breeders would allow reducing this

  7. Advances in molecular-based diagnostics in meeting crop biosecurity and phytosanitary issues.

    PubMed

    Schaad, Norman W; Frederick, Reid D; Shaw, Joe; Schneider, William L; Hickson, Robert; Petrillo, Michael D; Luster, Douglas G

    2003-01-01

    Awareness of crop biosecurity and phytosanitation has been heightened since 9/11 and the unresolved anthrax releases in October 2001. Crops are highly vulnerable to accidental or deliberate introductions of crop pathogens from outside U.S. borders. Strategic thinking about protection against deliberate or accidental release of a plant pathogen is an urgent priority. Rapid detection will be the key to success. This review summarizes recent progress in the development of rapid real-time PCR protocols and evaluates their effectiveness in a proposed nationwide network of diagnostic laboratories that will facilitate rapid diagnostics and improved communication.

  8. Value of information analysis as a decision support tool for biosecurity: Chapter 15

    USGS Publications Warehouse

    Runge, Michael C.; Rout, Tracy; Spring, Daniel; Walshe, Terry

    2017-01-01

    This chapter demonstrates the economic concept of ‘value of information’(VOI), and how biosecurity managers can use VOI analysis to decide whether or not to reduce uncertainty by collecting additional information through monitoring, experimentation, or some other form of research. We first explore how some uncertainties may be scientifically interesting to resolve, but ultimately irrelevant to decision-making. We then develop a prototype model where a manager must choose between eradication or containment of an infestation. Eradication is more cost-effective for smaller infestations, but once the extent reaches a certain size it becomes more cost-effective to contain. When choosing between eradication and containment, how much does knowing the extent of the infestation more exactly improve the outcome of the decision? We calculate the expected value of perfect information (EVPI) about the extent, which provides an upper limit for the value of reducing uncertainty. We then illustrate the approach using the example of red imported fire ant management in south-east Queensland. We calculate the EVPI for three different uncertain variables: the extent of the infestation, the sensitivity (true positive rate) of remote sensing, and the efficacy of baiting.

  9. Biosafety and Biosecurity: A Relative Risk-Based Framework for Safer, More Secure, and Sustainable Laboratory Capacity Building.

    PubMed

    Dickmann, Petra; Sheeley, Heather; Lightfoot, Nigel

    2015-01-01

    Laboratory capacity building is characterized by a paradox between endemicity and resources: countries with high endemicity of pathogenic agents often have low and intermittent resources (water, electricity) and capacities (laboratories, trained staff, adequate regulations). Meanwhile, countries with low endemicity of pathogenic agents often have high-containment facilities with costly infrastructure and maintenance governed by regulations. The common practice of exporting high biocontainment facilities and standards is not sustainable and concerns about biosafety and biosecurity require careful consideration. A group at Chatham House developed a draft conceptual framework for safer, more secure, and sustainable laboratory capacity building. The draft generic framework is guided by the phrase "LOCAL - PEOPLE - MAKE SENSE" that represents three major principles: capacity building according to local needs (local) with an emphasis on relationship and trust building (people) and continuous outcome and impact measurement (make sense). This draft generic framework can serve as a blueprint for international policy decision-making on improving biosafety and biosecurity in laboratory capacity building, but requires more testing and detailing development.

  10. Biosecurity and Health Monitoring at the Zebrafish International Resource Center

    PubMed Central

    Varga, Zoltán M.; Kent, Michael L.

    2016-01-01

    Abstract The Zebrafish International Resource Center (ZIRC) is a repository and distribution center for mutant, transgenic, and wild-type zebrafish. In recent years annual imports of new zebrafish lines to ZIRC have increased tremendously. In addition, after 15 years of research, we have identified some of the most virulent pathogens affecting zebrafish that should be avoided in large production facilities, such as ZIRC. Therefore, while importing a high volume of new lines we prioritize safeguarding the health of our in-house fish colony. Here, we describe the biosecurity and health-monitoring program implemented at ZIRC. This strategy was designed to prevent introduction of new zebrafish pathogens, minimize pathogens already present in the facility, and ensure a healthy zebrafish colony for in-house uses and shipment to customers. PMID:27031282

  11. Biosecurity and Circulation of Influenza A (H5N1) Virus in Live-Bird Markets in Bangladesh, 2012.

    PubMed

    Biswas, P K; Giasuddin, M; Nath, B K; Islam, M Z; Debnath, N C; Yamage, M

    2017-06-01

    Bangladesh has been considered as one of the five countries endemic with highly pathogenic avian influenza A subtype H5N1 (HPAI H5N1). Live-bird markets (LBMs) in south Asian countries are believed to play important roles in the transmission of HPAI H5N1 and others due to its central location as a hub of the poultry trading. Food and Agriculture Organization (FAO) of the United Nations has been promoting improved biosecurity in LBMs in Bangladesh. In 2012, by enrolling 32 large LBMs: 10 with FAO interventions and 22 without assistance, we assessed the virus circulation in the selected LBMs by applying standard procedures to investigate market floors, poultry stall floors, poultry-holding cases and slaughter areas and the overall biosecurity using a questionnaire-based survey. Relative risk (RR) was examined to compare the prevalence of HPAI H5N1 in the intervened and non-intervened LBMs. The measures practised in significantly more of the FAO-intervened LBMs included keeping of slaughter remnants in a closed container; decontamination of poultry vehicles at market place; prevention of crows' access to LBM, market/floor cleaning by market committee; wet cleaning; disinfection of floor/poultry stall after cleaning; and good supply of clean water at market (P < 0.05). Conversely, disposal of slaughter remnants elsewhere at market and dry cleaning were in operation in more of the FAO non-intervened LBMs (P < 0.05). The RR for HPAI H5N1 in the intervened and non-intervened LBMs was 1.1 (95% confidence interval 0.44-2.76), suggesting that the proportion positive of the virus in the two kinds of LBM did not vary significantly (P = 0.413). These observations suggest that the viruses are still maintained at the level of production in farms and circulating in LBMs in Bangladesh regardless of interventions, albeit at lower levels than in other endemic countries. © 2015 Blackwell Verlag GmbH.

  12. Live pig markets in eastern Indonesia: Trader characteristics, biosecurity and implications for disease spread.

    PubMed

    Leslie, Edwina E C; Geong, Maria; Abdurrahman, Muktasam; Ward, Michael P; Toribio, Jenny-Ann L M L

    2016-03-01

    Classical swine fever has been negatively impacting pig production in Nusa Tenggara Timur province in eastern Indonesia since its introduction in the 1990s, with live market trade contributing to disease spread. To understand market trader knowledge and practices regarding pig management, biosecurity, pig movements and pig health (specifically CSF), a repeated survey was conducted with pig sellers and pig buyers at 9 market sites across West Timor and the islands of Flores and Sumba. A total of 292 sellers and 281 buyers were interviewed in 2009 during two periods (rounds), a high-demand month (September) and a low-demand month (November). Information was collected via questionnaire. The majority of traders were male (sellers: 89%; buyers: 87%) with the highest level of completed education being primary school (sellers: 48%; buyers: 41%). The primary occupation of most respondents was farming: 90% of sellers and 87% of buyers were smallholder pig farmers and tended to sell their own home-raised pigs at market (52%). Pigs were sold for monetary gain either for primary (52%) or extra income (44%). Markets tended to be selected based on a good reputation (62%), a location close to residence (62%) and having the desired pig type (59%). Pig sales through markets were reported to be highest from August to October with 31% of sellers trading pigs at two or more markets. Prices at market were significantly higher on Sumba compared to West Timor and cross-bred pigs were significantly more expensive than indigenous pigs. Understanding of CSF and biosecurity was limited: 85% of sellers and 83% of buyers had no prior knowledge of CSF. Fifty-four percent of sellers reported no use of any biosecurity practices at market. Most respondents (88%) were able to recognise at least one clinical sign of a sick pig. Informal pig movements were also identified: 18% of pig buyers purchased pigs directly from other farmers. This study has provided baseline information on market trader

  13. Description of the pig production systems, biosecurity practices and herd health providers in two provinces with high swine density in the Philippines.

    PubMed

    Alawneh, J I; Barnes, T S; Parke, C; Lapuz, E; David, E; Basinang, V; Baluyut, A; Villar, E; Lopez, E L; Blackall, P J

    2014-05-01

    A cross-sectional study was conducted between October 2011 and March 2012 in two major pig producing provinces in the Philippines. Four hundred and seventy one pig farms slaughtering finisher pigs at government operated abattoirs participated in this study. The objectives of this study were to group: (a) smallholder (S) and commercial (C) production systems into patterns according to their herd health providers (HHPs), and obtain descriptive information about the grouped S and C production systems; and (b) identify key HHPs within each production system using social network analysis. On-farm veterinarians, private consultants, pharmaceutical company representatives, government veterinarians, livestock and agricultural technicians, and agricultural supply stores were found to be actively interacting with pig farmers. Four clusters were identified based on production system and their choice of HHPs. Differences in management and biosecurity practices were found between S and C clusters. Private HHPs provided a service to larger C and some larger S farms, and have little or no interaction with the other HHPs. Government HHPs provided herd health service mainly to S farms and small C farms. Agricultural supply stores were identified as a dominant solitary HHP and provided herd health services to the majority of farmers. Increased knowledge of the routine management and biosecurity practices of S and C farmers and the key HHPs that are likely to be associated with those practices would be of value as this information could be used to inform a risk-based approach to disease surveillance and control. Copyright © 2014 Elsevier B.V. All rights reserved.

  14. Biosecurity and Vector Behaviour: Evaluating the Potential Threat Posed by Anglers and Canoeists as Pathways for the Spread of Invasive Non-Native Species and Pathogens

    PubMed Central

    Anderson, Lucy G.; White, Piran C. L.; Stebbing, Paul D.; Stentiford, Grant D.; Dunn, Alison M.

    2014-01-01

    Invasive non-native species (INNS) endanger native biodiversity and are a major economic problem. The management of pathways to prevent their introduction and establishment is a key target in the Convention on Biological Diversity's Aichi biodiversity targets for 2020. Freshwater environments are particularly susceptible to invasions as they are exposed to multiple introduction pathways, including non-native fish stocking and the release of boat ballast water. Since many freshwater INNS and aquatic pathogens can survive for several days in damp environments, there is potential for transport between water catchments on the equipment used by recreational anglers and canoeists. To quantify this biosecurity risk, we conducted an online questionnaire with 960 anglers and 599 canoeists to investigate their locations of activity, equipment used, and how frequently equipment was cleaned and/or dried after use. Anglers were also asked about their use and disposal of live bait. Our results indicate that 64% of anglers and 78.5% of canoeists use their equipment/boat in more than one catchment within a fortnight, the survival time of many of the INNS and pathogens considered in this study and that 12% of anglers and 50% of canoeists do so without either cleaning or drying their kit between uses. Furthermore, 8% of anglers and 28% of canoeists had used their equipment overseas without cleaning or drying it after each use which could facilitate both the introduction and secondary spread of INNS in the UK. Our results provide a baseline against which to evaluate the effectiveness of future biosecurity awareness campaigns, and identify groups to target with biosecurity awareness information. Our results also indicate that the biosecurity practices of these groups must improve to reduce the likelihood of inadvertently spreading INNS and pathogens through these activities. PMID:24717714

  15. Establishing a national biological laboratory safety and security monitoring program.

    PubMed

    Blaine, James W

    2012-12-01

    The growing concern over the potential use of biological agents as weapons and the continuing work of the Biological Weapons Convention has promoted an interest in establishing national biological laboratory biosafety and biosecurity monitoring programs. The challenges and issues that should be considered by governments, or organizations, embarking on the creation of a biological laboratory biosafety and biosecurity monitoring program are discussed in this article. The discussion focuses on the following questions: Is there critical infrastructure support available? What should be the program focus? Who should be monitored? Who should do the monitoring? How extensive should the monitoring be? What standards and requirements should be used? What are the consequences if a laboratory does not meet the requirements or is not willing to comply? Would the program achieve the results intended? What are the program costs? The success of a monitoring program can depend on how the government, or organization, responds to these questions.

  16. Improvement in smallholder farmer knowledge of cattle production, health and biosecurity in Southern Cambodia between 2008 and 2010.

    PubMed

    Nampanya, S; Suon, S; Rast, L; Windsor, P A

    2012-04-01

    Farmer knowledge surveys were conducted in 2008 and 2010 in Cambodia to evaluate the impact of a research project studying interventions that can improve cattle production and health, including biosecurity and practices relating to risks of transmission of transboundary diseases. The project hypothesis is that by increasing the value of smallholder-owned large ruminants through nutritional interventions and improved marketing, knowledge-based interventions including risk management for infectious diseases such as foot-and-mouth disease (FMD) can be implemented into a more sustainable pathway for rural development. Between 2008 and 2010, significant improvements in farmer knowledge and attitudes were recorded in three villages in three provinces of southern Cambodia. This was achieved through participatory 'applied field research', 'on the job' training plus 'formal' training programmes. No cases of FMD were recorded during the study period in the 'high-intervention' (HI) villages despite the common occurrence of the disease in a nearby 'low-intervention' and many other villages in the three provinces. Whilst it is likely that protection of these villages from FMD infection was from increasing the herd immunity by vaccination, it could also have been partly because of a decrease in risk behaviours by farmers as a result of their increasing knowledge of biosecurity. The research indicates that smallholder farmers are motivated by nutritional interventions that improve the value of their cattle 'bank' and offer better marketing opportunities. This provides a more receptive environment for introduction of disease risk management for infectious and other production limiting diseases, best implemented for smallholder farmers in Cambodia by intensive training programmes. In lieu of a widespread public awareness programme to deliver mass education of smallholder farmers in disease prevention and biosecurity, livestock development projects in South-East Asia should be

  17. Setting priorities for non-regulatory animal health in Ireland: results from an expert Policy Delphi study and a farmer priority identification survey.

    PubMed

    More, Simon J; McKenzie, Ken; O'Flaherty, Joe; Doherty, Michael L; Cromie, Andrew R; Magan, Mike J

    2010-07-01

    Agriculture is a very important contributor to the Irish economy. In Ireland, national animal health services have been a government, rather than an industry, responsibility. In 2009, Animal Health Ireland (AHI) was established to provide a partnership approach to national leadership of non-regulatory animal health issues (those not subject to national and/or EU regulation). The objectives of this study were to elicit opinion from experts and farmers about non-regulatory animal health issues facing Irish livestock industries, including prioritisation of animal health issues and identification of opportunities to maximise the effective use of AHI resources. The study was conducted with experts using Policy Delphi methodology over three rounds, and with farmers using a priority identification survey. Non-regulatory bovine diseases/conditions were prioritised by both experts and farmers based on impact and international competitiveness. For each high-priority disease/condition, experts were asked to provide an assessment based on cost, impact, international perception, impediment to international market access and current resource usage effectiveness. Further information was also sought from experts about resource allocation preferences, methods to improve education and coordination, and innovative measures to improve prevention and management. There was close agreement between responses from experts and dairy farmers: each gave highest priority to 3 diseases with a biosecurity risk (subsequently termed 'biosecure diseases') (bovine viral diarrhoea [BVD], infectious bovine rhinotracheitis [IBR], paratuberculosis) and 4 diseases/conditions generally without a biosecurity risk ('non-biosecure diseases/conditions') (fertility, udder health/milk quality, lameness, calf health). Beef farmers also prioritised parasitic conditions and weanling pneumonia. The adverse impact of biosecure diseases is currently considered relatively minor by experts, but would increase

  18. Distinguishing Male and Female Chinese Rose Beetles, Adoretus sinicus, with an Overview of Adoretus Species of Biosecurity Concern

    PubMed Central

    McQuate, Grant T.; Jameson, Mary Liz

    2011-01-01

    The Chinese rose beetle, Adoretus sinicus Burmeister (Coleoptera: Scarabaeidae: Rutelinae: Adoretini), is a broadly polyphagous scarab beetle that is economically important and causes damage to a wide variety of host plants including agricultural crops and ornamentals in Southeast Asia, China, the Hawaiian Islands and several other Pacific Islands. The species has become established in numerous regions and is of biosecurity concern because importation of this species to other regions poses a threat to agriculture due to its generalist herbivore feeding habits. Field and laboratory research directed towards control of the species is hampered by the lack of characteristics that allow accurate determination of the sexes on live beetles in the field. Here, three recognizable and reliable non-destructive morphological differences between the sexes of A. sinicus are documented: (1) the form of the terminal sternite; (2) the length to width ratio of protarsomere 1, and; 3) the ratio of the combined length of protarsomeres 2–4 to the length of protarsomere 1. Because many Adoretus species are of biosecurity concern, and because tools to identify Adoretus species are lacking, we review the natural history and research on control associated with A. sinicus as well as the genus as a whole. PMID:21864158

  19. Linking Supply Chain Governance and Biosecurity in the Context of HPAI Control in Western Java: A Value Chain Perspective

    PubMed Central

    Indrawan, Dikky; Rich, Karl M.; van Horne, Peter; Daryanto, Arief; Hogeveen, Henk

    2018-01-01

    Despite extensive efforts to control the highly pathogenic avian influenza (HPAI), it remains endemic in Western Java, Indonesia. To understand the limited effectiveness of HPAI control measures, it is important to map the complex structure of the poultry sector. The governance of the poultry value chain in particular, could play a pivotal role, yet there is limited information on the different chain governance structures and their impacts on HPAI control. This article uses value chain analysis (VCA), focusing on an in-depth assessment of governance structures as well as transaction cost economics and quantitative estimates of the market power of different chain actors, to establish a theoretical framework to examine biosecurity and HPAI control in the Western Java poultry chain. During the research, semi-structured interviews were conducted with key value-chain stakeholders, and the economic performance of identified actors was estimated. Results indicated the co-existence of four different poultry value chains in West Java: the integrator chain, the semi-automated slaughterhouse chain, the controlled slaughter-point chain, and the private slaughter-point chain. The integrator chain was characterized by the highest levels of coordination and a tight, hierarchical governance. In contrast, the other three types of value chains were less coordinated. The market power of the different actors within the four value chains also differed. In more integrated chains, slaughterhouses held considerable market power, while in more informal value chains, market power was in the hands of traders. The economic effects of HPAI and biosecurity measures also varied for the identified actors in the different value chains. Implementation of biosecurity and HPAI control measures was strongly related to the governance structure of the chain, with interactions between different chains and governance structures accentuating the risk of HPAI. Our findings highlight that a proper

  20. Linking Supply Chain Governance and Biosecurity in the Context of HPAI Control in Western Java: A Value Chain Perspective.

    PubMed

    Indrawan, Dikky; Rich, Karl M; van Horne, Peter; Daryanto, Arief; Hogeveen, Henk

    2018-01-01

    Despite extensive efforts to control the highly pathogenic avian influenza (HPAI), it remains endemic in Western Java, Indonesia. To understand the limited effectiveness of HPAI control measures, it is important to map the complex structure of the poultry sector. The governance of the poultry value chain in particular, could play a pivotal role, yet there is limited information on the different chain governance structures and their impacts on HPAI control. This article uses value chain analysis (VCA), focusing on an in-depth assessment of governance structures as well as transaction cost economics and quantitative estimates of the market power of different chain actors, to establish a theoretical framework to examine biosecurity and HPAI control in the Western Java poultry chain. During the research, semi-structured interviews were conducted with key value-chain stakeholders, and the economic performance of identified actors was estimated. Results indicated the co-existence of four different poultry value chains in West Java: the integrator chain, the semi-automated slaughterhouse chain, the controlled slaughter-point chain, and the private slaughter-point chain. The integrator chain was characterized by the highest levels of coordination and a tight, hierarchical governance. In contrast, the other three types of value chains were less coordinated. The market power of the different actors within the four value chains also differed. In more integrated chains, slaughterhouses held considerable market power, while in more informal value chains, market power was in the hands of traders. The economic effects of HPAI and biosecurity measures also varied for the identified actors in the different value chains. Implementation of biosecurity and HPAI control measures was strongly related to the governance structure of the chain, with interactions between different chains and governance structures accentuating the risk of HPAI. Our findings highlight that a proper

  1. Real-time PCR detection of Didemnum perlucidum (Monniot, 1983) and Didemnum vexillum (Kott, 2002) in an applied routine marine biosecurity context.

    PubMed

    Simpson, Tiffany J S; Dias, P Joana; Snow, Michael; Muñoz, Julieta; Berry, Tina

    2017-05-01

    Prevention and early detection are well recognized as the best strategies for minimizing the risks posed by nonindigenous species (NIS) that have the potential to become marine pests. Central to this is the ability to rapidly and accurately identify the presence of NIS, often from complex environmental samples like biofouling and ballast water. Molecular tools have been increasingly applied to assist with the identification of NIS and can prove particularly useful for taxonomically difficult groups like ascidians. In this study, we have developed real-time PCR assays suited to the specific identification of the ascidians Didemnum perlucidum and Didemnum vexillum. Despite being recognized as important global pests, this is the first time specific molecular detection methods have been developed that can support the early identification and detection of these species from a broad range of environmental sample types. These fast, robust and high-throughput assays represent powerful tools for routine marine biosecurity surveillance, as detection and confirmation of the early presence of species could assist in the timely establishment of emergency responses and control strategies. This study applied the developed assays to confirm the ability to detect Didemnid eDNA in water samples. While previous work has focused on detection of marine larvae from water samples, the development of real-time PCR assays specifically aimed at detecting eDNA of sessile invertebrate species in the marine environment represents a world first and a significant step forwards in applied marine biosecurity surveillance. Demonstrated success in the detection of D. perlucidum eDNA from water samples at sites where it could not be visually identified suggests value in incorporating such assays into biosecurity survey designs targeting Didemnid species. © 2016 John Wiley & Sons Ltd.

  2. The De Novo Synthesis of Horsepox Virus: Implications for Biosecurity and Recommendations for Preventing the Reemergence of Smallpox.

    PubMed

    Koblentz, Gregory D

    In March 2017, the American biotech company Tonix announced that a Canadian scientist had synthesized horsepox virus as part of a project to develop a safer vaccine against smallpox. The first de novo synthesis of an orthopoxvirus, a closely related group of viruses that includes horsepox and the variola virus that causes smallpox, crosses an important Rubicon in the field of biosecurity. The synthesis of horsepox virus takes the world one step closer to the reemergence of smallpox as a threat to global health security. That threat has been held at bay for the past 40 years by the extreme difficulty of obtaining variola virus and the availability of effective medical countermeasures. The techniques demonstrated by the synthesis of horsepox have the potential to erase both of these barriers. The primary risk posed by this research is that it will open the door to the routine and widespread synthesis of other orthopoxviruses, such as vaccinia, for use in research, public health, and medicine. The normalization and globalization of orthopoxvirus synthesis for these beneficial applications will create a cadre of laboratories and scientists that will also have the capability and expertise to create infectious variola virus from synthetic DNA. Unless the safeguards against the synthesis of variola virus are strengthened, the capability to reintroduce smallpox into the human population will be globally distributed and either loosely or completely unregulated, providing the foundation for a disgruntled or radicalized scientist, sophisticated terrorist group, unscrupulous company, or rogue state to recreate one of humanity's most feared microbial enemies. The reemergence of smallpox-because of a laboratory accident or an intentional release-would be a global health disaster. International organizations, national governments, the DNA synthesis industry, and the synthetic biology community all have a role to play in devising new approaches to preventing the reemergence of

  3. Development and Evaluation of an On-Line Educational Module for Volunteer Leaders on Bio-Security in Washington State 4-H Livestock Projects

    ERIC Educational Resources Information Center

    Stevenson, Jill L.; Moore, Dale A.; Newman, Jerry; Schmidt, Janet L.; Smith, Sarah M.; Smith, Jean; Kerr, Susan; Wallace, Michael; BoyEs, Pat

    2011-01-01

    A module on disease prevention was created for 4-H volunteer leaders who work with livestock projects in Washington to better prepare them to teach youth about bio-security and its importance in 4-H livestock projects. Evaluation of the module and usage statistics since the module's debut were collected and evaluated. The module increases…

  4. Field application of a combined pig and poultry market chain and risk pathway analysis within the Pacific Islands region as a tool for targeted disease surveillance and biosecurity.

    PubMed

    Brioudes, Aurélie; Gummow, Bruce

    2016-07-01

    Limited resources are one of the major constraints in effective disease monitoring and control in developing countries. This paper examines the pig and poultry market chains of four targeted Pacific Island countries and territories (PICTs): Fiji, Papua New Guinea, Solomon Islands and Vanuatu and combines them with a risk pathway analysis to identify the highest risk areas (risk hotspots) and risky practices and behaviours (risk factors) of animal disease introduction and/or spread, using highly pathogenic avian influenza (HPAI) and foot-and-mouth disease (FMD) as model diseases because of their importance in the region. The results show that combining a market chain analysis with risk pathways is a practical way of communicating risk to animal health officials and improving biosecurity. It provides a participatory approach that helps officials to better understand the trading regulations in place in their country and to better evaluate their role as part of the control system. Common risk patterns were found to play a role in all four PICTs. Legal trade pathways rely essentially on preventive measures put in place in the exporting countries while no or only limited control measures are undertaken by the importing countries. Legal importations of animals and animal products are done mainly by commercial farms which then supply local smallholders. Targeting surveillance on these potential hotspots would limit the risk of introduction and spread of animal diseases within the pig and poultry industry and better rationalize use of skilled manpower. Swill feeding is identified as a common practice in the region that represents a recognized risk factor for dissemination of pathogens to susceptible species. Illegal introduction of animals and animal products is suspected, but appears restricted to small holder farms in remote areas, limiting the risk of spread of transboundary animal diseases along the market chain. Introduction of undeclared goods hidden within a legal

  5. Development and Evaluation of an On-Line Educational Module for Volunteer Leaders on Bio-Security in Washington State 4-H Livestock Projects

    ERIC Educational Resources Information Center

    Stevenson, Jill L.; Moore, Dale A.; Newman, Jerry; Schmidt, Janet L.; Smith, Sarah M.; Smith, Jean; Kerr, Susan; Wallace, Michael; BoyEs, Pat

    2011-01-01

    An on-line module on disease prevention was created for 4-H volunteer leaders who work with livestock projects in Washington to better prepare them to teach youth about bio-security and its importance in 4-H livestock projects. Evaluation of the module and usage statistics since the module's debut were collected and evaluated. The module increases…

  6. National mass care strategy: a national integrated approach.

    PubMed

    Mintz, Amy; Gonzalez, Waddy

    2013-01-01

    Mass care refers to a wide range of humanitarian activities that collectively provide life- sustaining services, such as emergency sheltering, feeding, reunification, distribution of emergency supplies and recovery information, before or in the aftermath of an emergency or disaster. Most services are coordinated and provided by non-governmental organisations and/or local government. Based on the lessons learned in the aftermath of Hurricanes Katrina and Rita in 2005, the American Red Cross, the Federal Emergency Management Agency and the National Voluntary Organizations Active in Disasters joined efforts to expand national mass care capabilities in order to support survivors in the wake of catastrophic events, as well as to enhance the integration of volunteers and non-governmental organisations into the broader national effort. These efforts resulted in the creation of the National Mass Care Council in 2010, with representatives of Federal and State agencies, voluntary organisations and the private sector working together to develop a unified approach to mass care and to ensure the provision of consistent and uniform services across the USA, regardless of the magnitude of the event.

  7. A biosecure composting system for disposal of cattle carcasses and manure following infectious disease outbreak.

    PubMed

    Xu, Weiping; Reuter, Tim; Inglis, G Douglas; Larney, Francis J; Alexander, Trevor W; Guan, Jiewen; Stanford, Kim; Xu, Yongping; McAllister, Tim A

    2009-01-01

    During outbreaks of infectious animal diseases, composting may be an effective method of disposing of mortalities and potentially contaminated manure. Duplicate biosecure structures containing 16 cattle (Bos taurus) mortalities (343 kg average weight) were constructed with carcasses placed on a 40-cm straw layer and overlaid with 160 cm of feedlot manure. At a depth of 80 cm (P80), compost heated rapidly, exceeding 55 degrees C after 8 d and maintained temperatures of 55 to 65 degrees C for > 35 d. Temperatures at 160 cm (P160) failed to exceed 55 degrees C, but remained above 40 degrees C for >4 mo. To investigate rates of microbial inactivation, Escherichia coli O157:H7, Campylobacter jejuni, and Newcastle disease virus (NDV) were inoculated in manure (E. coli O157:H7 and C. jejuni approximately 10(8) CFU g(-1); NDV, approximately 10(6) EID(50) g(-1)), embedded at P80 and P160 and retrieved at intervals during composting. Escherichia coli O157:H7 and NDV were undetectable after 7 d at both depths. The C. jejuni DNA was detected up to 84 d at P80 and >147 d at P160. To estimate degradation of recalcitrant substrates, bovine brain, hoof, and rib bones were also embedded at P80 and P160 and retrieved at intervals. Residues of soft tissues remained in carcasses after opening at 147 d and bovine tissue decomposition ranked as brain > hoof > bone. More than 90% dry matter (DM) of brain disappeared after 7 d and 80% DM of hoof decomposed after 56 d. High degradation of cattle carcasses, rapid suppression of E. coli O157:H7 and NDV and reduction in viable cell densities of >6 logs for C. jejuni demonstrates that the biosecure composting system can dispose of cattle carcasses and manure in an infectious disease outbreak.

  8. Biosecurity and animal disease management in organic and conventional Swedish dairy herds: a questionnaire study.

    PubMed

    Emanuelson, Ulf; Sjöström, Karin; Fall, Nils

    2018-04-12

    Good animal health is a notion that is germane to organic dairy production, and it is expected that such herds would pay significant attention on the health of their animals. However, it is not known if the applied animal disease management is actually more adequate in organic dairy cattle herds than in conventional dairy herds. A questionnaire study on biosecurity and animal disease management activities was therefore conducted among Swedish farmers with organic and conventional dairy cattle herds. A total of 192 useable questionnaires were returned; response rates of 30.3 and 20.2% for organic and conventional farmers, respectively. Herd characteristics of the two herd types were very similar, except that pipeline/tie-stall systems were less common in organic farms and that organic farmers had a higher education level than their conventional counterparts. Also, very few systematic differences in general or specific disease management activities were observed between the two types of farms. The main exceptions being how milk from cows during antibiotic treatment was used, views on policy actions in relation to antibiotic use, and attitudes towards calling for veterinary support. Using milk from cows during antibiotic treatment was more common in conventional herds, although it was mainly given to bull calves. Farmers of organic herds were more positive to policy actions to reduce the use and need for antibiotics, and they reported waiting longer before contacting a veterinarian for calves with diarrhoea and cows with subclinical mastitis. The stated biosecurity and animal disease management was relatively equal in Swedish organic and conventional dairy herds. Our results thus indicate that animal health is as important in conventionally managed dairy herds in Sweden as in organically managed herds.

  9. 76 FR 77240 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-12

    ... Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(d) of... the National Science Advisory Board for Biosecurity (NSABB). The meeting will be closed to the public... check this site for updates. Name of Committee: National Science Advisory Board for Biosecurity. Date...

  10. Calcinated egg shell as a candidate of biosecurity enhancement material

    PubMed Central

    OTA, Mari; TOYOFUKU, Chiharu; THAMMAKARN, Chanathip; SANGSRIRATANAKUL, Natthanan; YAMADA, Masashi; NAKAJIMA, Katsuhiro; KITAZAWA, Minori; HAKIM, Hakimullah; ALAM, Md. Shahin; SHOHAM, Dany; TAKEHARA, Kazuaki

    2016-01-01

    Calcinated egg shell (Egg-CaO), of which the main component is calcium oxide, was evaluated in the forms of powder and aqueous solutions for their efficacies as disinfectants against avian influenza virus (AIV), Newcastle disease virus (NDV), infectious bursal disease virus (IBDV), Salmonella Infantis and Escherichia coli. Egg-CaO powder inactivated these viruses within 3 min in the presence of 33% of fetal bovine serum (FBS). In Egg-CaO solutions, except AIV, all pathogens were inactivated within 1 hr, even in the presence of 5% of FBS. Without FBS, all pathogens, except AIV, were inactivated within 3 min, and AIV within 1 hr. In addition, persistence of virucidal activity against AIV and NDV of Egg-CaO powder was confirmed after exposure to sunlight for 2 weeks or resuspension with water for 7 times, simulating field harsh environments. Chick growth test was conducted to ensure the safety of the use of Egg-CaO powder in chicken cages and showed that it is safe to add Egg-CaO in litter or feed. In conclusion, Egg-CaO can be useful for the enhancement of biosecurity at farms. PMID:26854110

  11. The role of live poultry movement and live bird market biosecurity in the epidemiology of influenza A (H7N9): A cross-sectional observational study in four eastern China provinces.

    PubMed

    Zhou, Xiaoyan; Li, Yin; Wang, Youming; Edwards, John; Guo, Fusheng; Clements, Archie C A; Huang, Baoxu; Magalhaes, Ricardo J Soares

    2015-10-01

    A new reassortant influenza A (H7N9) virus emerged early 2013 in eastern China. Exposure to H7N9 infected poultry at live bird markets (LBM) was implicated as the main risk factor for human infection. We aimed to identify the role of LBM biosecurity indicators and poultry movement in the affected areas. A cross-sectional survey was carried out in 24 LBMs at the beginning of H7N9 outbreak in all affected provinces. We used univariable analysis to identify the biosecurity factors associated with the H7N9 presence in LBMs and social network and spatial analysis to quantify the connectivity and geographic variation in the connectivity of poultry movements. Chickens were the predominant poultry species traded by affected LBMs. The presence of H7N9 in LBMs was significantly associated with the type of LBM and with LBMs that sold chicken to other markets. The chicken movements were significantly spatially clustered and was highest in counties from Jiangsu and Anhui provinces. LBM biosecurity and chicken movement played an important role in the emergence of H7N9. This study identified highly connected areas in eastern China which continue to report human infections highlighting candidate areas for more detailed epidemiological investigations. Copyright © 2015 The British Infection Association. Published by Elsevier Ltd. All rights reserved.

  12. Detection and characterization of viruses of the genus Megalocytivirus in ornamental fish imported into an Australian border quarantine premises: an emerging risk to national biosecurity.

    PubMed

    Nolan, D; Stephens, F; Crockford, M; Jones, J B; Snow, M

    2015-02-01

    This report documents an emerging trend of identification of Megalocytivirus-like inclusions in a range of ornamental fish species intercepted during quarantine detention at the Australian border. From September 2012 to February 2013, 5 species of fish that had suffered mortality levels in excess of 25% whilst in the post-entry quarantine and had Megalocytivirus-like inclusion bodies in histological sections were examined by PCR. The fish had been imported from Singapore, Malaysia and Sri Lanka. Ninety-seven of 111 individual fish from affected tanks of fish tested were positive for the presence of Megalocytivirus by PCR. Sequence analysis of representative PCR products revealed an identical sequence of 621 bp in all cases which was identical to a previously characterized Megalocytivirus (Sabah/RAA1/2012 strain BMGIV48). Phylogenetic analysis of available Megalocytivirus major capsid protein (MCP) sequences confirmed the existence of 3 major clades of Megalocytivirus. The virus detected in this study was identified as a member of Genotype II. The broad host range and pathogenicity of megalocytiviruses, coupled to the documented spread of ornamental fish into the environment, render this a significant and emerging biosecurity threat to Australia. © 2014 John Wiley & Sons Ltd.

  13. Science and Security Clash on Bird-Flu Papers

    ERIC Educational Resources Information Center

    Fischman, Josh

    2012-01-01

    Censored papers on bird flu, which could help terrorists, have critics wondering if academic scientists can police their own work. The near-publication has brought out general critics of the federal panel, the National Science Advisory Board for Biosecurity, and the voluntary self-policing approach that it embraces instead of regulation. Members…

  14. The ABCs of the US Broad Spectrum Antimicrobials Program: Antibiotics, Biosecurity, and Congress

    PubMed Central

    2015-01-01

    Antibiotic resistance has been increasing at an alarming rate in the United States and globally for decades, but the problem has only recently gained broad attention at the highest levels of the US government. More and more patients are dying of infections that do not respond to antibiotics that are currently available. Meanwhile, the antibacterial product pipeline remains fragile in part because of a lack of commercial interest from pharmaceutical companies. The Biomedical Advanced Research and Development Authority (BARDA) Broad Spectrum Antimicrobials (BSA) program leads the US government's effort to bridge this gap by advancing new antibacterials through late stages of clinical development. Other commentators have described in detail BARDA's structure, process, and role in antibacterial development. This commentary offers a public policy perspective on the emerging politics of antibiotic resistance in the context of US biosecurity politics and medical countermeasure (MCM) development. It identifies promising developments and difficult challenges that together will ultimately determine whether BARDA can become a global leader for antibiotic development. PMID:26569379

  15. Embryo transfer: a comparative biosecurity advantage in international movements of germplasm.

    PubMed

    Thibier, M

    2011-04-01

    This paper uses cattle as a model to provide an overview of the hazards involved in the transfer of in vivo-derived and in vitro-produced embryos. While scientific studies in recent decades have led to the identification of pathogens that may be associated with both in vivo- and in vitro-derived embryos, those studies have also been the basis of appropriate disease control measures to reduce the risks to a negligible level. These disease control measures have been identified and assessed by the International Embryo Transfer Society's (lETS) Health and Safety Advisory Committee, the expert body that advises the World Organisation for Animal Health (OIE) on matters related to the safety of embryo transfer. Through the OIE's processes for developing and adopting international standards, the disease control measures identified by the IETS have been incorporated into the Terrestrial Animal Health Code. The basic principles rely on the crucial ethical roles of the embryo collection team and embryo transfer team, under the leadership of approved veterinarians. Decades of experience, with nearly 10 million embryos transferred, have demonstrated the very significant biosecurity advantage that embryo transfer technology has when moving germplasm internationally, provided that the international standards developed by the IETS and adopted by the OIE are strictly followed.

  16. Oversight of Dual-Use Biological Research: The National Science Advisory Board for Biosecurity

    DTIC Science & Technology

    2006-07-10

    on the origins of virulence, the development of vaccines , and the genetic manipulation of biological agents are simultaneously relevant to public...treatments, vaccines and other prophylactic measures, and detection methods). ! Advise on national policies governing publication, public communication, and...October 6, 2005, pp. 889-893. 9 For example, see Sabin Russell, “Deadliest Flu Bug Given New Life in U.S. Laboratory; Some Applaud Scientific Feat

  17. Towards a global barcode library for Lymantria (Lepidoptera: Lymantriinae) tussock moths of biosecurity concern.

    PubMed

    deWaard, Jeremy R; Mitchell, Andrew; Keena, Melody A; Gopurenko, David; Boykin, Laura M; Armstrong, Karen F; Pogue, Michael G; Lima, Joao; Floyd, Robin; Hanner, Robert H; Humble, Leland M

    2010-12-09

    Detecting and controlling the movements of invasive species, such as insect pests, relies upon rapid and accurate species identification in order to initiate containment procedures by the appropriate authorities. Many species in the tussock moth genus Lymantria are significant forestry pests, including the gypsy moth Lymantria dispar L., and consequently have been a focus for the development of molecular diagnostic tools to assist in identifying species and source populations. In this study we expand the taxonomic and geographic coverage of the DNA barcode reference library, and further test the utility of this diagnostic method, both for species/subspecies assignment and for determination of geographic provenance of populations. Cytochrome oxidase I (COI) barcodes were obtained from 518 individuals and 36 species of Lymantria, including sequences assembled and generated from previous studies, vouchered material in public collections, and intercepted specimens obtained from surveillance programs in Canada. A maximum likelihood tree was constructed, revealing high bootstrap support for 90% of species clusters. Bayesian species assignment was also tested, and resulted in correct assignment to species and subspecies in all instances. The performance of barcoding was also compared against the commonly employed NB restriction digest system (also based on COI); while the latter is informative for discriminating gypsy moth subspecies, COI barcode sequences provide greater resolution and generality by encompassing a greater number of haplotypes across all Lymantria species, none shared between species. This study demonstrates the efficacy of DNA barcodes for diagnosing species of Lymantria and reinforces the view that the approach is an under-utilized resource with substantial potential for biosecurity and surveillance. Biomonitoring agencies currently employing the NB restriction digest system would gather more information by transitioning to the use of DNA barcoding, a

  18. Assessment of farmer knowledge of large ruminant health and production in developing village-level biosecurity in northern Lao PDR.

    PubMed

    Nampanya, S; Rast, L; Khounsy, S; Windsor, P A

    2010-12-01

    The purpose of this study was to determine baseline knowledge and identify knowledge gaps of farmers on biosecurity, risk of transmission of transboundary diseases and large ruminant health and production in three provinces of northern Laos, Hua Phan (HP), Luang Prabang (LPB) and Xieng Khoung (XK). The survey was conducted in six villages that are project sites for an Australian Centre for International Agricultural Research (ACIAR) project, with two villages located in each of the three provinces. A census survey was conducted by interview with all 238 farmers participating in the ACIAR project, using a structured questionnaire. The interviews were conducted in Lao language and took 1-2 h per farmer. The answers were recorded in Lao and the survey data were translated into English and transcribed into Microsoft Excel, and a linear mixed model in the Genstat statistical analysis package was used to compare quantitative traits between the target provinces. The results showed that the prediction mean of farmer knowledge scores on parasitic disorders, infectious disease, reproduction and nutrition management were significantly different between the target provinces. The prediction mean of farmer knowledge scores on infectious disease questions ranged between 5.11 in HP to 8.54 in XK of 24 marks (P < 0.001). The prediction mean of total knowledge scores was 13.48 in LPB and 19.29 in XK of 42 marks (P < 0.001). The results indicate both the need for and scope required to attain improvements in farmer knowledge of large ruminant health and production. It was concluded that a participatory research and extension programme to address village-level biosecurity and reduce disease risks, plus enhance large ruminant production capabilities of smallholder producers, is a valid and potentially important strategy to address transboundary disease risk and rural poverty in northern Laos. © 2010 Blackwell Verlag GmbH.

  19. Crying wolf? Biosecurity and metacommunication in the context of the 2009 swine flu pandemic.

    PubMed

    Nerlich, Brigitte; Koteyko, Nelya

    2012-07-01

    This article explores how the 2009 pandemic of swine flu (H1N1) intersected with issues of biosecurity in the context of an increasing entanglement between the spread of disease and the spread of information. Drawing on research into metacommunication, the article studies the rise of communication about ways in which swine flu was communicated, both globally and locally, during the pandemic. It examines and compares two corpora of texts, namely UK newspaper articles and blogs, written between 28 March and 11 June 2009, that is, the period from the start of the outbreak till the WHO announcement of the pandemic. Findings show that the interaction between traditional and digital media as well as the interaction between warnings about swine flu and previous warnings about other epidemics contributed to a heightened discourse of blame and counter-blame but also, more surprisingly, self-blame and reflections about the role the media in pandemic communication. The consequences of this increase in metacommunication for research into crisis communication are explored. Copyright © 2011 Elsevier Ltd. All rights reserved.

  20. The Role of a National Biocontainment Laboratory in Emergencies.

    PubMed

    Le Duc, James W; Ksiazek, Thomas G

    2015-01-01

    Over a decade ago, the National Institutes of Health awarded partial support for the construction and operation of 2 National Biocontainment Laboratories, with the condition that they would be available to assist in the event of public health emergencies-although how a biocontainment facility located on an academic campus might contribute was not defined. Here we offer examples of how one of these laboratories has contributed to a coordinated response to 2 recent international public health emergencies. Essential assets for success include highly trained and experienced staff, access to reference pathogens and reagents, cutting-edge knowledge of the field, appropriate biocontainment facilities, robust biosafety and biosecurity programs, and availability of modern instrumentation. The ability to marry the strengths of academia in basic and applied research with access to appropriate biocontainment facilities while drawing on a highly skilled cadre of experienced experts has proven extremely valuable in the response to recent national emergencies and will continue to do so in the future. Areas where additional planning and preparation are needed have also been identified through these experiences.

  1. Health information exchange: national and international approaches.

    PubMed

    Vest, Joshua R

    2012-01-01

    Health information exchange (HIE), the process of electronically moving patient-level information between different organizations, is viewed as a solution to the fragmentation of data in health care. This review provides a description of the current state of HIE in seven nations, as well was three international HIE efforts, with a particular focus on the relation of exchange efforts to national health care systems, common challenges, and the implications of cross-border information sharing. National and international efforts highlighted in English language informatics journals, professional associations, and government reports are described. Fully functioning HIE is not yet a common phenomenon worldwide. However, multiple nations see the potential benefits of HIE and that has led to national and international efforts of varying scope, scale, and purview. National efforts continue to work to overcome the challenges of interoperability, record linking, insufficient infrastructures, governance, and interorganizational relationships, but have created architectural strategies, oversight agencies, and incentives to foster exchange. The three international HIE efforts reviewed represent very different approaches to the same problem of ensuring the availability of health information across borders. The potential of HIE to address many cost and quality issues will ensure HIE remains on many national agendas. In many instances, health care executives and leaders have opportunities to work within national programs to help shape local exchange governance and decide technology partners. Furthermore, HIE raises policy questions concerning the role of centralized planning, national identifiers, standards, and types of information exchanged, each of which are vital issues to individual health organizations and worthy of their attention.

  2. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas.

    PubMed

    Yeh, Kenneth B; Adams, Martin; Stamper, Paul D; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D; Richards, Allen L; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community.

  3. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas

    PubMed Central

    Adams, Martin; Stamper, Paul D.; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D.; Richards, Allen L.; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community. PMID:27559843

  4. Wanted dead or alive? Using metabarcoding of environmental DNA and RNA to distinguish living assemblages for biosecurity applications

    PubMed Central

    Zaiko, Anastasija; Fletcher, Lauren M.; Laroche, Olivier; Wood, Susanna A.

    2017-01-01

    High-throughput sequencing metabarcoding studies in marine biosecurity have largely focused on targeting environmental DNA (eDNA). DNA can persist extracellularly in the environment, making discrimination of living organisms difficult. In this study, bilge water samples (i.e., water accumulating on-board a vessel during transit) were collected from 15 small recreational and commercial vessels. eDNA and eRNA molecules were co-extracted and the V4 region of the 18S ribosomal RNA gene targeted for metabarcoding. In total, 62.7% of the Operational Taxonomic Units (OTUs) were identified at least once in the corresponding eDNA and eRNA reads, with 19.5% unique to eDNA and 17.7% to eRNA. There were substantial differences in diversity between molecular compartments; 57% of sequences from eDNA-only OTUs belonged to fungi, likely originating from legacy DNA. In contrast, there was a higher percentage of metazoan (50.2%) and ciliate (31.7%) sequences in the eRNA-only OTUs. Our data suggest that the presence of eRNA-only OTUs could be due to increased cellular activities of some rare taxa that were not identified in the eDNA datasets, unusually high numbers of rRNA transcripts in ciliates, and/or artefacts produced during the reverse transcriptase, PCR and sequencing steps. The proportions of eDNA/eRNA shared and unshared OTUs were highly heterogeneous within individual bilge water samples. Multiple factors including boat type and the activities performed on-board, such as washing of scientific equipment, may play a major role in contributing to this variability. For some marine biosecurity applications analysis, eDNA-only data may be sufficient, however there are an increasing number of instances where distinguishing the living portion of a community is essential. For these circumstances, we suggest only including OTUs that are present in both eDNA and eRNA data. OTUs found only in the eRNA data need to be interpreted with caution until further research provides conclusive

  5. Wanted dead or alive? Using metabarcoding of environmental DNA and RNA to distinguish living assemblages for biosecurity applications.

    PubMed

    Pochon, Xavier; Zaiko, Anastasija; Fletcher, Lauren M; Laroche, Olivier; Wood, Susanna A

    2017-01-01

    High-throughput sequencing metabarcoding studies in marine biosecurity have largely focused on targeting environmental DNA (eDNA). DNA can persist extracellularly in the environment, making discrimination of living organisms difficult. In this study, bilge water samples (i.e., water accumulating on-board a vessel during transit) were collected from 15 small recreational and commercial vessels. eDNA and eRNA molecules were co-extracted and the V4 region of the 18S ribosomal RNA gene targeted for metabarcoding. In total, 62.7% of the Operational Taxonomic Units (OTUs) were identified at least once in the corresponding eDNA and eRNA reads, with 19.5% unique to eDNA and 17.7% to eRNA. There were substantial differences in diversity between molecular compartments; 57% of sequences from eDNA-only OTUs belonged to fungi, likely originating from legacy DNA. In contrast, there was a higher percentage of metazoan (50.2%) and ciliate (31.7%) sequences in the eRNA-only OTUs. Our data suggest that the presence of eRNA-only OTUs could be due to increased cellular activities of some rare taxa that were not identified in the eDNA datasets, unusually high numbers of rRNA transcripts in ciliates, and/or artefacts produced during the reverse transcriptase, PCR and sequencing steps. The proportions of eDNA/eRNA shared and unshared OTUs were highly heterogeneous within individual bilge water samples. Multiple factors including boat type and the activities performed on-board, such as washing of scientific equipment, may play a major role in contributing to this variability. For some marine biosecurity applications analysis, eDNA-only data may be sufficient, however there are an increasing number of instances where distinguishing the living portion of a community is essential. For these circumstances, we suggest only including OTUs that are present in both eDNA and eRNA data. OTUs found only in the eRNA data need to be interpreted with caution until further research provides conclusive

  6. Negative impact of laws regarding biosecurity and bioterrorism on real diseases.

    PubMed

    Wurtz, N; Grobusch, M P; Raoult, D

    2014-06-01

    Research on highly pathogenic microorganisms in biosafety level 3 and 4 laboratories is very important for human public health, as it provides opportunities for the development of vaccines and novel therapeutics as well as diagnostic methods to prevent epidemics. However, in recent years, after the anthrax and World Trade Center attacks in 2001 in the USA, the threat of bioterrorism has grown for both the public and the authorities. As a result, technical and physical containment measures and biosafety and biosecurity practices have been implemented in laboratories handling these dangerous pathogens. Working with selected biological agents and toxins is now highly regulated, owing to their potential to pose a threat to public health and safety, despite the fact that the anthrax attack was found to be the result of a lack of security at a US Army laboratory. Thus, these added regulations have been associated with a large amount of fruitless investment. Herein, we describe the limitations of research in these facilities, and the multiple consequences of the increased regulations. These limitations have seriously negatively impacted on the number of collaborations, the size of research projects, and, more generally, scientific research on microbial pathogens. Clearly, the actual number of known victims and fatalities caused by the intentional use of microorganisms has been negligible as compared with those caused by naturally acquired human infections. © 2014 The Authors Clinical Microbiology and Infection © 2014 European Society of Clinical Microbiology and Infectious Diseases.

  7. The animal-human interface and infectious disease in industrial food animal production: rethinking biosecurity and biocontainment.

    PubMed

    Graham, Jay P; Leibler, Jessica H; Price, Lance B; Otte, Joachim M; Pfeiffer, Dirk U; Tiensin, T; Silbergeld, Ellen K

    2008-01-01

    Understanding interactions between animals and humans is critical in preventing outbreaks of zoonotic disease. This is particularly important for avian influenza. Food animal production has been transformed since the 1918 influenza pandemic. Poultry and swine production have changed from small-scale methods to industrial-scale operations. There is substantial evidence of pathogen movement between and among these industrial facilities, release to the external environment, and exposure to farm workers, which challenges the assumption that modern poultry production is more biosecure and biocontained as compared with backyard or small holder operations in preventing introduction and release of pathogens. An analysis of data from the Thai government investigation in 2004 indicates that the odds of H5N1 outbreaks and infections were significantly higher in large-scale commercial poultry operations as compared with backyard flocks. These data suggest that successful strategies to prevent or mitigate the emergence of pandemic avian influenza must consider risk factors specific to modern industrialized food animal production.

  8. Biosecurity protocols for heritage gardens

    Treesearch

    Ian Wright; David Slawson

    2010-01-01

    This project aims to protect The National Trust (NT) from the increasing number of harmful plant pests and diseases that slip though official controls and threaten our gardens, plant collections and landscapes. During 2008, the National Trust (NT) with the seconded help of Dr. David Slawson, Head of Pest and Disease Identification Programme, Food and Environment...

  9. Toward a national health risk management approach in Australia.

    PubMed

    O'Donnell, Carol

    2002-01-01

    There has been increasing international consensus about the importance of competition for achieving national growth and community well-being. The Australian government accordingly has introduced policies to promote such competition. Major legislative review and many public inquiries have assisted implementation of national competition policy and the development of national goals and standards related to international agreements to promote health and sustainable development. Since the 1980s, Australia has had legislation that requires the identification and control of health risks arising at work. The management structures necessary for coordinated delivery of national programs designed for effective identification and control of health risks arising in communities to achieve national health and development goals are still being developed, however. Major difficulties related to this development are discussed. National health development programs should be approached primarily through establishment of regional partnerships between bodies responsible for managing community health, local government, and employment placement, in consultation with other relevant organizations and the community. Related research and evaluation programs are required.

  10. A Framework for the Evaluation of Biosecurity, Commercial, Regulatory, and Scientific Impacts of Plant Viruses and Viroids Identified by NGS Technologies

    PubMed Central

    Massart, Sebastien; Candresse, Thierry; Gil, José; Lacomme, Christophe; Predajna, Lukas; Ravnikar, Maja; Reynard, Jean-Sébastien; Rumbou, Artemis; Saldarelli, Pasquale; Škorić, Dijana; Vainio, Eeva J.; Valkonen, Jari P. T.; Vanderschuren, Hervé; Varveri, Christina; Wetzel, Thierry

    2017-01-01

    Recent advances in high-throughput sequencing technologies and bioinformatics have generated huge new opportunities for discovering and diagnosing plant viruses and viroids. Plant virology has undoubtedly benefited from these new methodologies, but at the same time, faces now substantial bottlenecks, namely the biological characterization of the newly discovered viruses and the analysis of their impact at the biosecurity, commercial, regulatory, and scientific levels. This paper proposes a scaled and progressive scientific framework for efficient biological characterization and risk assessment when a previously known or a new plant virus is detected by next generation sequencing (NGS) technologies. Four case studies are also presented to illustrate the need for such a framework, and to discuss the scenarios. PMID:28174561

  11. [THE ACTUAL APPROACHES TO PROBLEM OF IMPORT SUBSTITUTION IN TH FIELD OF PRODUCTION GROWTH MEDIUM].

    PubMed

    Shepelin, A P; Domotenko, L V; Diatlov, I A; Mironov, A Yu; Aleshkin, V A

    2015-06-01

    The import substitution becomes one of strategic tasks of Russian economy as a result of imposition of economic sanctions on part of the USA, EU countries, Japan and number of other states. The development of structure and technology of production of national import substituted growth mediums permits satisfying needs of laboratory service of Russia inactive storage and to secure appropriate response to occurring challenges and new biological menaces and support bio-security of state at proper level. The presented data concerning substantiation of nomenclature of growth mediums and transport system permit satisfying in fullness the needs of clinical and sanitary microbiology in growth mediums of national production and to give up of import deliveries without decreasing of quality of microbiological studies.

  12. A Blended Approach to Canadian First Nations Education

    ERIC Educational Resources Information Center

    Sacher, Martin; Sacher, Mavis; Vaughan, Norman

    2014-01-01

    The purpose of this research study was to investigate if and how a blended approach to Canadian First Nations education could be used to foster student engagement and success. The study examined the SCcyber E-Learning Community program (2012) through the lens of the "Seven Principles of Effective Teaching" (Chickering & Gamson,…

  13. Bulk tank milk antibody ELISA as a biosecurity tool for detecting dairy herds with past exposure to Mycoplasma bovis.

    PubMed

    Parker, A M; House, J K; Hazelton, M S; Bosward, K L; Morton, J M; Sheehy, P A

    2017-10-01

    In Australia, one of the biosecurity recommendations to help prevent the introduction of Mycoplasma bovis into a dairy herd is to use a PCR assay on bulk tank milk (BTM) samples to evaluate the M. bovis infection status of potential source herds. An alternative approach is to assess the immunological status of the herd with respect to previous exposure to M. bovis via the use of an ELISA that is commercially available for use on cattle milk and serum. The objectives of this study were to (1) evaluate factors potentially associated with variation in the ELISA BTM optical density coefficient (ODC%) in previously exposed herds, (2) evaluate the association between the proportion of cows that are ELISA positive and the BTM ELISA ODC%, (3) assess agreement between the BTM ELISA and PCR and culture, and (4) compare BTM ELISA ODC% between the "hospital" herd and the main lactating herd on the same farm. Bulk tank milk samples (n = 192) were collected from 19 dairy herds with a history of clinical M. bovis disease and from 6 control herds (herds with no known clinical cases of mycoplasmosis). For 28 of the BTM samples collected, blood was also collected from 50 lactating cows contributing to that bulk tank sample. From 1 herd, concurrent paired BTM samples were collected from the main herd and the hospital herd on 16 occasions. All BTM samples were analyzed by ELISA (Bio-X Bio K 302, Bio-X Diagnostics, Rochefort, Belgium), PCR, and culture. The BTM ELISA ODC% was associated with time since initial M. bovis outbreak and time since the start of the herd's calving period. Following an initial outbreak of M. bovis, the BTM ELISA ODC% was highest in the first 8 mo. In split- and seasonal-calving herds, significantly higher BTM ELISA ODC% results were observed 5 to 8 wk after the commencement of the calving period. A significant association was observed between the within-herd seroprevalence for the lactating herd and BTM ELISA ODC%, but within-herd seroprevalence explained

  14. Defining "Sector 3" Poultry Layer Farms in Relation to H5N1-HPAI-An Example from Java, Indonesia.

    PubMed

    Durr, Peter A; Wibowo, Michael Haryadi; Tarigan, Simson; Artanto, Sidna; Rosyid, Murni Nurhasanah; Ignjatovic, Jagoda

    2016-05-01

    To help guide surveillance and control of highly pathogenic avian influenza subtype H5N1 (H5N1-HPAI), the Food and Agriculture Organization of the United Nations in 2004 devised a poultry farm classification system based on a combination of production and biosecurity practices. Four "Sectors" were defined, and this scheme has been widely adopted within Indonesia to guide national surveillance and control strategies. Nevertheless, little detailed research into the robustness of this classification system has been conducted, particularly as it relates to independent, small to medium-sized commercial poultry farms (Sector 3). Through an analysis of questionnaire data collected as part of a survey of layer farms in western and central Java, all of which were classified as Sector 3 by local veterinarians, we provide benchmark data on what defines this sector. A multivariate analysis of the dataset, using hierarchical cluster analysis, identified three groupings of the farms, which were defined by a combination of production-and biosecurity-related variables, particularly those related to farm size and (the lack of) washing and disinfection practices. Nevertheless, the relationship between production-related variables and positive biosecurity practices was poor, and larger farms did not have an overall higher total biosecurity score than small or medium-sized ones. Further research is required to define the properties of poultry farms in Indonesia that are most closely related to effective biosecurity and the prevention of H5N1-HPAI.

  15. The effect of animal health compensation on 'positive' behaviours towards exotic disease reporting and implementing biosecurity: A review, a synthesis and a research agenda.

    PubMed

    Barnes, Andrew Peter; Moxey, Andrew Paul; Vosough Ahmadi, Bouda; Borthwick, Fiona Ann

    2015-11-01

    With an increasing burden on public sector budgets, increased responsibility and cost sharing mechanisms for animal diseases are being considered. To achieve this, fiscal and non-fiscal intervention policies need to be designed such that they consistently promote positive disease risk management practices by animal keepers. This paper presents a review of the available evidence towards whether and how the level and type of funding mechanism affects change within biosecurity behaviours and the frequency of disease reporting. A Nuffield Health Ladder of Interventions approach is proposed as a way to frame the debate surrounding both current compensation mechanisms and how it is expected to change behaviour. Results of the review reveal a division between economic modelling approaches, which implicitly assume a causal link between payments and positive behaviours, and socio-geographic approaches which tend to ignore the influence of compensation mechanisms on influencing behaviours. Generally, economic studies suggest less than full compensation rates will encourage positive behaviours, but the non-economic literature indicate significant variation in response to compensation reflecting heterogeneity of livestock keepers in terms of their values, goals, risk attitudes, size of operation, animal species and production chain characteristics. This may be of encouragement to Western Governments seeking to shift cost burdens as it may induce greater targeting of non-fiscal mechanisms, or suggest more novel ways to augment current compensation mechanisms to both increase responsibility sharing and reduce this cost burden. This review suggests that a range of regulatory, fiscal and nudging policies are required to achieve socially optimal results with respect to positive behaviour change. However, the lack of directly available evidence which proves these causal links may hinder progress towards this optimal mixture of choice and non-choice based interventions. Copyright

  16. Edutourism Taka Bonerate National Park through Scientific Approach to Improve Student Learning Outcomes

    NASA Astrophysics Data System (ADS)

    Hayati, R. S.

    2017-02-01

    This research aim is develop the potential of Taka Bonerate National Park as learning resources through edutourism with scientific approach to improve student learning outcomes. Focus of student learning outcomes are students psychomotor abilities and comprehension on Biodiversity of Marine Biota, Corals Ecosystem, and Conservation topics. The edutourism development products are teacher manual, edutourism worksheet, material booklet, guide’s manual, and Taka Bonerate National Park governor manual. The method to develop edutourism products is ADDIE research and development model that consist of analysis, design, development and production, implementation, and evaluation step. The subjects in the implementation step were given a pretest and posttest and observation sheet to see the effect of edutourism Taka Bonerate National Park through scientific approach to student learning outcomes on Biodiversity of Marine Biota, Corals Ecosystem, and Conservation topics. The data were analyzed qualitative descriptively. The research result is edutourism Taka Bonerate National Park through scientific approach can improve students learning outcomes on Biodiversity of Marine Biota, Corals Ecosystem, and Conservation topics. Edutourism Taka Bonerate National Park can be an alternative of learning method on Biodiversity of Marine Biota, Corals Ecosystem, and Conservation topics.

  17. A Complexity Approach to Evaluating National Scientific Systems through International Scientific Collaborations

    ERIC Educational Resources Information Center

    Zelnio, Ryan J.

    2013-01-01

    This dissertation seeks to contribute to a fuller understanding of how international scientific collaboration has affected national scientific systems. It does this by developing three methodological approaches grounded in social complexity theory and applying them to the evaluation of national scientific systems. The first methodology identifies…

  18. Establishment of Canada's National Forest Inventory: Approach and Issues

    Treesearch

    A. Y. Omule; Mark D. Gillis

    2005-01-01

    This paper describes Canada's National Forest Inventory (NFI) sampling design and implementation. It also describes issues related to annualizing the NFI using the approach of the U.S. Department of Agriculture Forest Service Enhanced Forest Inventory and Analysis program as a model. It concludes with an outline of plans to address the inventory annualization...

  19. Effectiveness of biosecurity measures in preventing badger visits to farm buildings.

    PubMed

    Judge, Johanna; McDonald, Robbie A; Walker, Neil; Delahay, Richard J

    2011-01-01

    Bovine tuberculosis caused by Mycobacterium bovis is a serious and economically important disease of cattle. Badgers have been implicated in the transmission and maintenance of the disease in the UK since the 1970s. Recent studies have provided substantial evidence of widespread and frequent visits by badgers to farm buildings during which there is the potential for close direct contact with cattle and contamination of cattle feed. Here we evaluated the effectiveness of simple exclusion measures in improving farm biosecurity and preventing badger visits to farm buildings. In the first phase of the study, 32 farms were surveyed using motion-triggered infrared cameras on potential entrances to farm buildings to determine the background level of badger visits experienced by each farm. In the second phase, they were divided into four treatment groups; "Control", "Feed Storage", "Cattle Housing" and "Both", whereby no exclusion measures were installed, exclusion measures were installed on feed storage areas only, cattle housing only or both feed storage and cattle housing, respectively. Badger exclusion measures included sheet metal gates, adjustable metal panels for gates, sheet metal fencing, feed bins and electric fencing. Cameras were deployed for at least 365 nights in each phase on each farm. Badger visits to farm buildings occurred on 19 of the 32 farms in phase one. In phase two, the simple exclusion measures were 100% effective in preventing badger entry into farm buildings, as long as they were appropriately deployed. Furthermore, the installation of exclusion measures also reduced the level of badger visits to the rest of the farmyard. The findings of the present study clearly demonstrate how relatively simple practical measures can substantially reduce the likelihood of badger visits to buildings and reduce some of the potential for contact and disease transmission between badgers and cattle.

  20. Control strategies against Campylobacter at the poultry production level: biosecurity measures, feed additives and vaccination.

    PubMed

    Meunier, M; Guyard-Nicodème, M; Dory, D; Chemaly, M

    2016-05-01

    Campylobacteriosis is the most prevalent bacterial foodborne gastroenteritis affecting humans in the European Union, and ranks second in the United States only behind salmonellosis. In Europe, there are about nine million cases of campylobacteriosis every year, making the disease a major public health issue. Human cases are mainly caused by the zoonotic pathogen Campylobacter jejuni. The main source of contamination is handling or consumption of poultry meat. Poultry constitutes the main reservoir of Campylobacter, substantial quantities of which are found in the intestines following rapid, intense colonization. Reducing Campylobacter levels in the poultry chain would decrease the incidence of human campylobacteriosis. As primary production is a crucial step in Campylobacter poultry contamination, controlling the infection at this level could impact the following links along the food chain (slaughter, retail and consumption). This review describes the control strategies implemented during the past few decades in primary poultry production, including the most recent studies. In fact, the implementation of biosecurity and hygiene measures is described, as well as the immune strategy with passive immunization and vaccination trials and the nutritional strategy with the administration of organic and fatty acids, essential oil and plant-derived compound, probiotics, bacteriocins and bacteriophages. © 2015 The Society for Applied Microbiology.

  1. Benchmarking in the National Intellectual Capital Measurement: Is It the Best Available Approach?

    ERIC Educational Resources Information Center

    Januškaite, Virginija; Užiene, Lina

    2016-01-01

    Sustainable economic development is an aspiration of every nation in today's knowledge economy. Scientists for a few decades claim that intellectual capital management is the answer how to reach this goal. Currently, benchmarking methodology is the most common approach in the national intellectual capital measurement intended to provide…

  2. Maintenance of Fish Health in Aquaculture: Review of Epidemiological Approaches for Prevention and Control of Infectious Disease of Fish.

    PubMed

    Assefa, Ayalew; Abunna, Fufa

    2018-01-01

    Aquaculture is rapidly growing part of agriculture worldwide. It makes up around 44 percent of total fish production globally. This increased growth of production is achieved despite facing many challenges in the aquaculture environment. Among production limiting challenges, the infectious disease takes the lion share by causing multibillion-dollar loss annually. To reduce the impact of the fish disease, it is necessary to address health constraints based on scientifically proven and recommended ways. This review aims at pointing out some of the best approaches to prevention and control of infectious disease in aquaculture. Among the effective prevention and control strategies, vaccination is one of the key practices. Types of vaccines for use in fish include killed vaccines, attenuated vaccines, DNA vaccines, recombinant technology vaccines, and synthetic peptide vaccines. Administration techniques of vaccines in fish include oral, injection, or immersion methods. Antibiotics are also in use in aquaculture despite their side effects in the development of drug resistance by microorganisms. Biological and chemical disease control strategies such as using probiotics, prebiotics, and medicinal plants are widely in use. Biosecurity measures in aquaculture can keep the safety of a facility from certain disease-causing agents that are absent in particular system. Farm-level biosecurity measures include strict quarantine measures, egg disinfection, traffic control, water treatments, clean feed, and disposal of mortalities. In conclusion, rather than trying to treat every disease case, it advisable to follow a preventive approach before the event of any disease outbreaks.

  3. Practical problems in controlling H5N1 high pathogenicity avian influenza at village level in Vietnam and introduction of biosecurity measures.

    PubMed

    Cristalli, Alessandro; Capua, Ilaria

    2007-03-01

    After a consultancy mission funded by a nongovernmental organization (NGO), information was collected on the dynamics of avian influenza (AI) infection at the rural level in a Vietnamese province with several ongoing outbreaks. AI outbreaks are frequent at village level due to environmental, ecological, agroecological, physical, social, and cultural factors, the underlying factor being poor hygienic conditions. Viral circulation is facilitated by the interactions of the integrated aquaculture, animal raising, horticulture agroecosystem, which relies in the peculiar integration of aquaculture (ponding), animal activities, and horticulture and by the connections with the live-bird market system. The interactions of these factors determine the complex system in which wild birds interact with domestic birds and in which people are constantly exposed to sources of infection, leading to the association between poverty and AI infection in humans. This experience underlines that despite all efforts by the Vietnamese Government, international institutions, and the NGO sector, awareness of AI at the village level needs to be improved. In turn, the leading institutions and international donors funding projects of technical cooperation aimed at tackling AI in Vietnam should invest in a system based on a deep knowledge of the practical problems of village condition to address AI with an effective approach. On the basis of the data collected during the mission, particularly on rural and semi-intensive poultry rearing systems, proposals that encompass the application of an effective vaccination strategy including backyard flocks coupled with dissemination of relevant information on biosecurity measures have been developed for decision makers.

  4. Performance of a plastic-wrapped composting system for biosecure emergency disposal of disease-related swine mortalities.

    PubMed

    Glanville, Thomas D; Ahn, Heekwon; Akdeniz, Neslihan; Crawford, Benjamin P; Koziel, Jacek A

    2016-02-01

    A passively-ventilated plastic-wrapped composting system initially developed for biosecure disposal of poultry mortalities caused by avian influenza was adapted and tested to assess its potential as an emergency disposal option for disease-related swine mortalities. Fresh air was supplied through perforated plastic tubing routed through the base of the compost pile. The combined air inlet and top vent area is ⩽∼1% of the gas exchange surface of a conventional uncovered windrow. Parameters evaluated included: (1) spatial and temporal variations in matrix moisture content (m.c.), leachate production, and matrix O2 concentrations; (2) extent of soft tissue decomposition; and (3) internal temperature and the success rate in achieving USEPA time/temperature (T) criteria for pathogen reduction. Six envelope materials (wood shavings, corn silage, ground cornstalks, ground oat straw, ground soybean straw, or ground alfalfa hay) and two initial m.c.'s (15-30% w.b. for materials stored indoors, and 45-65% w.b. to simulate materials exposed to precipitation) were tested to determine their effect on performance parameters (1-3). Results of triple-replicated field trials showed that the composting system did not accumulate moisture despite the 150kg carcass water load (65% of 225kg total carcass mass) released during decomposition. Mean compost m.c. in the carcass layer declined by ∼7 percentage points during 8-week trials, and a leachate accumulation was rare. Matrix O2 concentrations for all materials other than silage were ⩾10% using the equivalent of 2m inlet/vent spacing. In silage O2 dropped below 5% in some cases even when 0.5m inlet/vent spacing was used. Eight week soft tissue decomposition ranged from 87% in cornstalks to 72% in silage. Success rates for achievement of USEPA Class B time/temperature criteria ranged from 91% for silage to 33-57% for other materials. Companion laboratory biodegradation studies suggest that Class B success rates can be improved

  5. A watershed approach to ecosystem monitoring in Denali National Park and preserve, Alaska

    USGS Publications Warehouse

    Thorsteinson, L.K.; Taylor, D.L.

    1997-01-01

    The National Park Service and the National Biological Service initiated research in Denali National Park and Preserve, a 2.4 million-hectare park in southcentral Alaska, to develop ecological monitoring protocols for national parks in the Arctic/Subarctic biogeographic area. We are focusing pilot studies on design questions, on scaling issues and regionalization, ecosystem structure and function, indicator selection and evaluation, and monitoring technologies. Rock Creek, a headwater stream near Denali headquarters, is the ecological scale for initial testing of a watershed ecosystem approach. Our conceptual model embraces principles of the hydrological cycle, hypotheses of global climate change, and biological interactions of organisms occupying intermediate, but poorly studied, positions in Alaskan food webs. The field approach includes hydrological and depositional considerations and a suite of integrated measures linking key aquatic and terrestrial biota, environmental variables, or defined ecological processes, in order to establish ecological conditions and detect, track, and understand mechanisms of environmental change. Our sampling activities include corresponding measures of physical, chemical, and biological attributes in four Rock Creek habitats believed characteristic of the greater system diversity of Denali. This paper gives examples of data sets, program integration and scaling, and research needs.

  6. 77 FR 54584 - Final Action Under the NIH Guidelines for Research Involving Recombinant DNA Molecules (NIH...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-05

    ... National Institutes of Health (NIH) Office of Biotechnology Activities, Office of Science Policy (NIH/OBA... in the life sciences, such as directed molecular evolution and viral reverse genetics, has the... synthetic biology), and (2) a recommendation from the National Science Advisory Board for Biosecurity (NSABB...

  7. 75 FR 58410 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(a) of... of the National Science Advisory Board for Biosecurity (NSABB). Name of Committee: National Science... on Codes of Conduct; Culture of Responsibility; International Engagement; Journal Review Policies...

  8. A novel system architecture for the national integration of electronic health records: a semi-centralized approach.

    PubMed

    AlJarullah, Asma; El-Masri, Samir

    2013-08-01

    The goal of a national electronic health records integration system is to aggregate electronic health records concerning a particular patient at different healthcare providers' systems to provide a complete medical history of the patient. It holds the promise to address the two most crucial challenges to the healthcare systems: improving healthcare quality and controlling costs. Typical approaches for the national integration of electronic health records are a centralized architecture and a distributed architecture. This paper proposes a new approach for the national integration of electronic health records, the semi-centralized approach, an intermediate solution between the centralized architecture and the distributed architecture that has the benefits of both approaches. The semi-centralized approach is provided with a clearly defined architecture. The main data elements needed by the system are defined and the main system modules that are necessary to achieve an effective and efficient functionality of the system are designed. Best practices and essential requirements are central to the evolution of the proposed architecture. The proposed architecture will provide the basis for designing the simplest and the most effective systems to integrate electronic health records on a nation-wide basis that maintain integrity and consistency across locations, time and systems, and that meet the challenges of interoperability, security, privacy, maintainability, mobility, availability, scalability, and load balancing.

  9. Global challenges/chemistry solutions: Promoting personal safety and national security

    USDA-ARS?s Scientific Manuscript database

    Joe Alper: Can you provide a little background about why there is a need for this type of assay? Mark Carter: Ricin is considered a biosecurity threat agent. A more efficient detection method was required. Joe Alper: How are these type of assays done today, or are current methods unsuitable for ...

  10. Opinions of veterinarians on antimicrobial use in farm animals in Flanders and the Netherlands.

    PubMed

    Postma, M; Speksnijder, D C; Jaarsma, A D C; Verheij, T J M; Wagenaar, J A; Dewulf, J

    2016-07-16

    Veterinarians play an important role in the reduction of antimicrobial use in farm animals. This study aims to quantify opinions of veterinarians from the Netherlands and Flanders regarding antimicrobial use and resistance issues in farm animals. An online survey was sent out to 678 and 1100 farm animal veterinarians in Flanders and the Netherlands, of which 174 and 437 were returned respectively. Suboptimal climate conditions were regarded as the most important cause for high antimicrobial use in farm animals. Flemish veterinarians also regarded insufficient biosecurity measures and farmers' mentality as important determinants, while the Dutch respondents ranked insufficient immunity of young animals and economic considerations of farmers as major causes. The majority of Dutch respondents (63.8 per cent) supported the existing national policy, which aimed to halve veterinary antimicrobial use, while the Flemish (32.9 per cent) were less supportive of such a policy. Improvements in housing and climate conditions, biosecurity measures and strict control of specific infectious diseases were seen as important and promising measures to reduce antimicrobial use. To reduce antimicrobial use in farm animals, some shared approaches might be applicable in both countries. However, cultural, political and societal differences between Flanders and the Netherlands require differentiated approaches to reduce veterinary antimicrobial use. British Veterinary Association.

  11. Monitoring amphibians in Great Smoky Mountains National Park

    USGS Publications Warehouse

    Dodd, C. Kenneth

    2003-01-01

    This report provides an overview of the Park’s amphibians, the factors affecting their distribution, a review of important areas of biodiversity, and a summary of amphibian life history in the Southern Appalachians. In addition, survey techniques are described as well as examples of how the techniques are set up, a critique of what the results tell the observer, and a discussion of the limitations of the techniques and the data. The report reviews considerations for site selection, outlines steps for biosecurity and for processing diseased or dying animals, and provides resource managers with a decision tree on how to monitor the Park’s amphibians based on different levels of available resources. It concludes with an extensive list of references for inventorying and monitoring amphibians. USGS and Great Smoky Mountains National Park biologists need to establish cooperative efforts and training to ensure that congressionally mandated amphibian surveys are performed in a statistically rigorous and biologically meaningful manner, and that amphibian populations on Federal lands are monitored to ensure their long-term survival. The research detailed in this report will aid these cooperative efforts.

  12. Fundamental economic irreversibilities influence policies for enhancing international forest phytosanitary security

    Treesearch

    Thomas P. Holmes; Will Allen; Robert G. Haight; E. Carina H. Keskitalo; Mariella Marzano; Maria Pettersson; Christopher P. Quine; E. R. Langer

    2017-01-01

    National and international efforts to manage forest biosecurity create tension between opposing sources of ecological and economic irreversibility. Phytosanitary policies designed to protect national borders from biological invasions incur sunk costs deriving from economic and political irreversibilities that incentivizes wait-and-see decision-making. However, the...

  13. 76 FR 3918 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-21

    ... Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(a) of... of the National Science Advisory Board for Biosecurity (NSABB). Name of Committee: National Science... Engagement; Journal Review Policies; and Outreach and Education activities, including as well as possible...

  14. Approach of regionalisation c-stocks in forest soils on a national level

    NASA Astrophysics Data System (ADS)

    Wellbrock, Nicole; Höhle, Juliane; Dühnelt, Petra; Holzhausen, Marieanna

    2010-05-01

    Introduction In December 2006, the German government decided to manage forests as carbon sinks to reduce greenhouse gas emissions in accordance with Article 3.4 of the Kyoto Protocol. The National Forest Monitoring data contribute to the fulfilment of these reporting commitments. In Germany, National Forest Monitoring includes the systematical extensive National Soil Condition Survey (BZE) and the detailed case studies (Level-II) which determine the processes within forests. This complex monitoring system is appropriate to Germany's greenhouse gas reporting (THG 2008 to 2012). The representative BZE plots can be used to obtain regional data for the National Carbon Stock Inventory. Here, an approach adopting a combination of geostatistics and regression analysis is preferred. The difficulty of showing the statistical significance of expected small changes while carbon stocks are generally high is one of the major challenges in carbon stock monitoring. However, through intensive preparation and cooperation with the forestry authorities of each federal state, the errors uncured in determining changes in carbon stocks in forest soils, which must be stipulated in greenhouse gas monitoring, could be minimised. In contrast to the detailed soil case studies, in which essentially the sources of error occur repeatedly in carbon stock change calculations, the BZE data can be stratified to form plots with homogenous properties, thereby reducing the standard error of estimate. Subsequently, the results of the stratification are projected across Germany, the reporting unit for greenhouse gas monitoring. National Forest Monitoring The BZE represents a national, systematic sampling inventory of the condition of forest soils. The first BZE inventory (BZE I: 1987 to 1993) was carried out on a systematic 8 x 8 km grid on the same sampling plots adopted in the Forest Condition Survey (WZE). In some areas the network of sampling plots involves 1900 grid points. The first BZE I survey

  15. Resolving the double tension: Toward a new approach to measurement modeling in cross-national research

    NASA Astrophysics Data System (ADS)

    Medina, Tait Runnfeldt

    The increasing global reach of survey research provides sociologists with new opportunities to pursue theory building and refinement through comparative analysis. However, comparison across a broad array of diverse contexts introduces methodological complexities related to the development of constructs (i.e., measurement modeling) that if not adequately recognized and properly addressed undermine the quality of research findings and cast doubt on the validity of substantive conclusions. The motivation for this dissertation arises from a concern that the availability of cross-national survey data has outpaced sociologists' ability to appropriately analyze and draw meaningful conclusions from such data. I examine the implicit assumptions and detail the limitations of three commonly used measurement models in cross-national analysis---summative scale, pooled factor model, and multiple-group factor model with measurement invariance. Using the orienting lens of the double tension I argue that a new approach to measurement modeling that incorporates important cross-national differences into the measurement process is needed. Two such measurement models---multiple-group factor model with partial measurement invariance (Byrne, Shavelson and Muthen 1989) and the alignment method (Asparouhov and Muthen 2014; Muthen and Asparouhov 2014)---are discussed in detail and illustrated using a sociologically relevant substantive example. I demonstrate that the former approach is vulnerable to an identification problem that arbitrarily impacts substantive conclusions. I conclude that the alignment method is built on model assumptions that are consistent with theoretical understandings of cross-national comparability and provides an approach to measurement modeling and construct development that is uniquely suited for cross-national research. The dissertation makes three major contributions: First, it provides theoretical justification for a new cross-national measurement model and

  16. Influenza A virus in swine breeding herds: Combination of vaccination and biosecurity practices can reduce likelihood of endemic piglet reservoir.

    PubMed

    White, L A; Torremorell, M; Craft, M E

    2017-03-01

    Recent modelling and empirical work on influenza A virus (IAV) suggests that piglets play an important role as an endemic reservoir. The objective of this study is to test intervention strategies aimed at reducing the incidence of IAV in piglets and ideally, preventing piglets from becoming exposed in the first place. These interventions include biosecurity measures, vaccination, and management options that swine producers may employ individually or jointly to control IAV in their herds. We have developed a stochastic Susceptible-Exposed-Infectious-Recovered-Vaccinated (SEIRV) model that reflects the spatial organization of a standard breeding herd and accounts for the different production classes of pigs therein. Notably, this model allows for loss of immunity for vaccinated and recovered animals, and for vaccinated animals to have different latency and infectious periods from unvaccinated animals as suggested by the literature. The interventions tested include: (1) varied timing of gilt introductions to the breeding herd, (2) gilt separation (no indirect transmission to or from the gilt development unit), (3) gilt vaccination upon arrival to the farm, (4) early weaning, and (5) vaccination strategies of sows with different timing (mass and pre-farrow) and efficacy (homologous vs. heterologous). We conducted a Latin Hypercube Sampling and Partial Rank Correlation Coefficient (LHS-PRCC) analysis combined with a random forest analysis to assess the relative importance of each epidemiological parameter in determining epidemic outcomes. In concert, mass vaccination, early weaning of piglets (removal 0-7days after birth), gilt separation, gilt vaccination, and longer periods between introductions of gilts (6 months) were the most effective at reducing prevalence. Endemic prevalence overall was reduced by 51% relative to the null case; endemic prevalence in piglets was reduced by 74%; and IAV was eliminated completely from the herd in 23% of all simulations. Importantly

  17. Natural resource assessment: an approach to science based planning in national parks

    USGS Publications Warehouse

    Mahan, C.G.; Vanderhorst, J.P.; Young, J.A.

    2009-01-01

    We conducted a natural resource assessment at two national parks, New River Gorge National River and Shenandoah National Park, to help meet the goals of the Natural Resource Challenge-a program to help strengthen natural resource management at national parks. We met this challenge by synthesizing and interpreting natural resource information for planning purposes and we identified information gaps and natural significance of resources. We identified a variety of natural resources at both parks as being globally and/or nationally significant, including large expanses of unfragmented, mixed-mesophytic forests that qualify for wilderness protection, rare plant communities, diverse assemblages of neotropical migratory birds and salamanders, and outstanding aquatic recreational resources. In addition, these parks function, in part, as ecological reserves for plants in and wildlife. With these significant natural resources in mind, we also developed a suite of natural resource management recommendations in light of increasing threats from within and outside park boundaries. We hope that our approach can provide a blueprint for natural resource conservation at publically owned lands.

  18. Natural resource assessment: an approach to science based planning in national parks.

    PubMed

    Mahan, Carolyn G; Vanderhorst, James P; Young, John A

    2009-06-01

    We conducted a natural resource assessment at two national parks, New River Gorge National River and Shenandoah National Park, to help meet the goals of the Natural Resource Challenge--a program to help strengthen natural resource management at national parks. We met this challenge by synthesizing and interpreting natural resource information for planning purposes and we identified information gaps and natural significance of resources. We identified a variety of natural resources at both parks as being globally and/or nationally significant, including large expanses of unfragmented, mixed-mesophytic forests that qualify for wilderness protection, rare plant communities, diverse assemblages of neotropical migratory birds and salamanders, and outstanding aquatic recreational resources. In addition, these parks function, in part, as ecological reserves for plants in and wildlife. With these significant natural resources in mind, we also developed a suite of natural resource management recommendations in light of increasing threats from within and outside park boundaries. We hope that our approach can provide a blueprint for natural resource conservation at publically owned lands.

  19. National approaches to promote sports and physical activity in adults with disabilities: examples from the Netherlands and Canada.

    PubMed

    Hoekstra, Femke; Roberts, Lynn; van Lindert, Caroline; Martin Ginis, Kathleen A; van der Woude, Lucas H V; McColl, Mary Ann

    2018-01-15

    This study described how the Dutch and Canadian governments promote high performance sports, recreational sports, and physical activity (PA) among adults with disabilities on a national level. An internet-based study was conducted to identify and select relevant documents and websites containing information about the national approach to promote disability sports and physical activities in the Netherlands and Canada. Both governments promote high performance sports in similar ways, but use different strategies to promote recreational sports and physical activities. The Dutch approach is characterized by using time-limited programs focusing on enhancement of sports infrastructure and inter-sector collaboration in which municipalities have key roles. The Canadian government promotes recreational sports in disabled populations by supporting programs via bilateral agreements with provinces and territories. Furthermore, the level of integration of disability sports into mainstream sports differs between countries. The findings of this study may inspire policy makers from different countries to learn from one another's policies in order to optimize national approaches to promote disability sports and PA on all levels. Implications for rehabilitation It is recommended for policy makers of national governments to develop and implement policy programs that promote sports and physical activities among people with disabilities because of its potential impact on functioning, participation, quality of life, and health. Insight into national approaches to promote sport and physical activities is relevant for rehabilitation practice to understand ongoing opportunities for people with disabilities to stay physically active after rehabilitation through participation in home and/or community-based sport and physical activities. It seems worthwhile to integrate activities to promote sport and physical activities in rehabilitation in such a way that it fits with the current

  20. Invasive Cerambycid pests and biosecurity measures

    Treesearch

    Dominic Eyre; Robert A. Haack

    2017-01-01

    Longhorn beetles (Cerambycidae) in general, and some species in particular, have increased in importance for national and regional plant protection agencies over recent decades. Expensive eradication campaigns have been carried out in order to eliminate some longhorn beetles. For example, the cost of eradication campaigns undertaken between 1996 and 2013 against the...

  1. Use of herd information for predicting Salmonella status in pig herds.

    PubMed

    Baptista, F M; Alban, L; Nielsen, L R; Domingos, I; Pomba, C; Almeida, V

    2010-11-01

    Salmonella surveillance-and-control programs in pigs are highly resource demanding, so alternative cost-effective approaches are desirable. The aim of this study was to develop and evaluate a tool for predicting the Salmonella test status in pig herds based on herd information collected from 108 industrial farrow-to-finish pig herds in Portugal. A questionnaire including known risk factors for Salmonella was used. A factor analysis model was developed to identify relevant factors that were then tested for association with Salmonella status. Three factors were identified and labelled: general biosecurity (factor 1), herd size (factor 2) and sanitary gap implementation (factor 3). Based on the loadings in factor 1 and factor 3, herds were classified according to their biosecurity practices. In total, 59% of the herds had a good level of biosecurity (interpreted as a loading below zero in factor 1) and 37% of the farms had good biosecurity and implemented sanitary gap (loading below zero in factor 1 and loading above zero in factor 3). This implied that they, among other things, implemented preventive measures for visitors and workers entering the herd, controlled biological vectors, had hygiene procedures in place, water quality assessment, and sanitary gap in the fattening and growing sections. In total, 50 herds were tested for Salmonella. Logistic regression analysis showed that factor 1 was significantly associated with Salmonella test status (P = 0.04). Herds with poor biosecurity had a higher probability of testing Salmonella positive compared with herds with good biosecurity. This study shows the potential for using herd information to classify herds according to their Salmonella status in the absence of good testing options. The method might be used as a potentially cost-effective tool for future development of risk-based approaches to surveillance, targeting interventions to high-risk herds or differentiating sampling strategies in herds with different

  2. Evaluation Approaches for a National ICT Initiative: The Example of Laptops for New Zealand Teachers

    ERIC Educational Resources Information Center

    Jones, Alister; Cowie, Bronwen

    2011-01-01

    This paper will highlight the successful evaluation approaches deployed for long-term exploration of the impact of a national policy initiative as well as some of the results and outcomes. An interactive feedback process informed decision-making at the national and local level thereby enhancing both the initiative and its implementation in…

  3. An Integrated Library Platform: Wales' Approach to Delivering Digital Information and Resources Nationally

    ERIC Educational Resources Information Center

    Bevan, Paul; Tyler, Alyson

    2009-01-01

    Purpose: This paper aims to outline the developments and strategies employed to supply online library services in Wales through a national platform: library.wales.org These services include: the "Cat Cymru" cross-catalogue search, centrally procured subscription resources and local library microsites. Design/methodology/approach: The…

  4. Out-of-Pocket Expenditures on Complementary Health Approaches Associated with Painful Health Conditions in a Nationally Representative Adult Sample

    PubMed Central

    Nahin, Richard L.; Stussman, Barbara J.; Herman, Patricia M.

    2015-01-01

    National surveys suggest that millions of adults in the United States use complementary health approaches such as acupuncture, chiropractic manipulation, and herbal medicines to manage painful conditions such as arthritis, back pain and fibromyalgia. Yet, national and per person out-of-pocket (OOP) costs attributable to this condition-specific use are unknown. In the 2007 National Health Interview Survey, use of complementary health approaches, reasons for this use, and associated OOP costs were captured in a nationally representative sample of 5,467 adults. Ordinary least square regression models that controlled for co-morbid conditions were used to estimate aggregate and per person OOP costs associated with 14 painful health conditions. Individuals using complementary approaches spent a total of $14.9 billion (S.E. $0.9 billion) OOP on these approaches to manage these painful conditions. Total OOP expenditures seen in those using complementary approaches for their back pain ($8.7 billion, S.E. $0.8 billion) far outstripped that of any other condition, with the majority of these costs ($4.7 billion, S.E. $0.4 billion) resulting from visits to complementary providers. Annual condition-specific per-person OOP costs varied from a low of $568 (SE $144) for regular headaches, to a high of $895 (SE $163) for fibromyalgia. PMID:26320946

  5. Developing a national approach to building healthy and sustainable cities.

    PubMed

    Howe, Renate T

    2007-01-01

    Effective strategies to build a national approach to the integration of health and urban planning at all levels of government is essential if the health problems of urban Australians, such as obesity and respiratory illnesses, are to improve. This paper examines some policies and initiatives that could facilitate intergovernment cooperation on health and sustainability within the constraints of Australia's federal government system. These include recommendations for an Australian Sustainability Commission and Charter of Sustainability, evaluations of the Better Cities Program of the 1990s, and current proposals for improving urban governance to enable the implementation of a healthy and sustainable cities agenda.

  6. 75 FR 52504 - Notice of Request for Approval of an Information Collection; National Animal Health Monitoring...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-26

    ... and management practices for dairy heifer raising operations. Evaluate the biosecurity risks... used to evaluate the risk of disease transmission, e.g., TB and BVD, on dairy heifer raising operations... descriptive reports for DCHA members and each participating State and a summary report. Information will be...

  7. The unexpected discovery of Brucella abortus Buck 19 vaccine in goats from Ecuador underlines the importance of biosecurity measures.

    PubMed

    Ron-Román, Jorge; Berkvens, Dirk; Barzallo-Rivadeneira, Daniela; Angulo-Cruz, Alexandra; González-Andrade, Pablo; Minda-Aluisa, Elizabeth; Benítez-Ortíz, Washington; Brandt, Jef; Rodríguez-Hidalgo, Richar; Saegerman, Claude

    2017-03-01

    Very few, mostly old, and only preliminary serological studies of brucellosis in goats exist in Ecuador. In order to assess the current epidemiological situation, we performed a cross-sectional serological study in the goat populations of Carchi (n = 160 animals), Pichincha (n = 224 animals), and Loja provinces (n = 2024 animals). Only two positive serological results (RB negative and SAT-EDTA ≥400 IU/ml) were obtained in lactating goats from the same farm in Quito (Pichincha province). Additionally, milk was sampled from 220 animals in Pichincha province. The present study indicates a low apparent prevalence in Pichincha province and absence in Carchi and Loja provinces. A total of 25 positive milk ring tests (MRT) were obtained in Pichincha province yielding a prevalence of MRT of 11.16%. Subsequent culture was performed on the positive MRT samples. All results were negative, apart from a single sample, obtained from a serologically positive goat in Quito, that was positive for Brucella abortus strain 19 (B19). Several hypotheses are forwarded concerning this unexpected result. The most likely hypothesis is the possible accidental use of a needle, previously used for vaccination of cattle with the said vaccine, for the administration of drug treatment to the goat. This hypothesis underlines the necessity of biosecurity measures to prevent this type of accidents.

  8. Management Enhancement Team Approach (META) for the Australian National Training Authority. An Evaluation Report.

    ERIC Educational Resources Information Center

    Foreman, David J.; Dunn, John G.

    The management enhancement team approach (META) is a team-driven management development program designed for managers within Australia's National Vocational Education and Training Sector (NVETS). META, which has been piloted at more than 70 sites across Australia, is designed to identify and address management development needs within the context…

  9. Applying the Innov8 approach for reviewing national health programmes to leave no one behind: lessons learnt from Indonesia

    PubMed Central

    Saint, Victoria; Floranita, Rustini; Koemara Sakti, Gita Maya; Pambudi, Imran; Hermawan, Lukas; Villar, Eugenio; Magar, Veronica

    2018-01-01

    ABSTRACT The World Health Organization’s Innov8 Approach for Reviewing National Health Programmes to Leave No One Behind is an eight-step process that supports the operationalization of the Sustainable Development Goals’ commitment to ‘leave no one behind’. In 2014–2015, Innov8 was adapted and applied in Indonesia to review how the national neonatal and maternal health action plans could become more equity-oriented, rights-based and gender-responsive, and better address critical social determinants of health. The process was led by the Indonesian Ministry of Health, with the support of WHO. It involved a wide range of actors and aligned with/fed into the drafting of the maternal newborn health action plan and the implementation planning of the newborn action plan. Key activities included a sensitization meeting, diagnostic checklist, review workshop and in-country work by the review teams. This ‘methods forum’ article describes this adaptation and application process, the outcomes and lessons learnt. In conjunction with other sources, Innov8 findings and recommendations informed national and sub-national maternal and neonatal action plans and programming to strengthen a ‘leave no one behind’ approach. As follow-up during 2015–2017, components of the Innov8 methodology were integrated into district-level planning processes for maternal and newborn health, and Innov8 helped generate demand for health inequality monitoring and its use in planning. In Indonesia, Innov8 enhanced national capacity for equity-oriented, rights-based and gender-responsive approaches and addressing critical social determinants of health. Adaptation for the national planning context (e.g. decentralized structure) and linking with health inequality monitoring capacity building were important lessons learnt. The pilot of Innov8 in Indonesia suggests that this approach can help operationalize the SDGs’ commitment to leave no one behind, in particular in relation to

  10. Applying the Innov8 approach for reviewing national health programmes to leave no one behind: lessons learnt from Indonesia.

    PubMed

    Koller, Theadora Swift; Saint, Victoria; Floranita, Rustini; Koemara Sakti, Gita Maya; Pambudi, Imran; Hermawan, Lukas; Briot, Benedicte; Frenz, Patricia; Solar, Orielle; Campos, Pilar; Villar, Eugenio; Magar, Veronica

    The World Health Organization's Innov8 Approach for Reviewing National Health Programmes to Leave No One Behind is an eight-step process that supports the operationalization of the Sustainable Development Goals' commitment to 'leave no one behind'. In 2014-2015, Innov8 was adapted and applied in Indonesia to review how the national neonatal and maternal health action plans could become more equity-oriented, rights-based and gender-responsive, and better address critical social determinants of health. The process was led by the Indonesian Ministry of Health, with the support of WHO. It involved a wide range of actors and aligned with/fed into the drafting of the maternal newborn health action plan and the implementation planning of the newborn action plan. Key activities included a sensitization meeting, diagnostic checklist, review workshop and in-country work by the review teams. This 'methods forum' article describes this adaptation and application process, the outcomes and lessons learnt. In conjunction with other sources, Innov8 findings and recommendations informed national and sub-national maternal and neonatal action plans and programming to strengthen a 'leave no one behind' approach. As follow-up during 2015-2017, components of the Innov8 methodology were integrated into district-level planning processes for maternal and newborn health, and Innov8 helped generate demand for health inequality monitoring and its use in planning. In Indonesia, Innov8 enhanced national capacity for equity-oriented, rights-based and gender-responsive approaches and addressing critical social determinants of health. Adaptation for the national planning context (e.g. decentralized structure) and linking with health inequality monitoring capacity building were important lessons learnt. The pilot of Innov8 in Indonesia suggests that this approach can help operationalize the SDGs' commitment to leave no one behind, in particular in relation to influencing programming and monitoring

  11. Advancing reference emission levels in subnational and national REDD+ initiatives: a CLASlite approach

    PubMed Central

    Asner, Gregory P; Joseph, Shijo

    2015-01-01

    Conservation and monitoring of tropical forests requires accurate information on their extent and change dynamics. Cloud cover, sensor errors and technical barriers associated with satellite remote sensing data continue to prevent many national and sub-national REDD+ initiatives from developing their reference deforestation and forest degradation emission levels. Here we present a framework for large-scale historical forest cover change analysis using free multispectral satellite imagery in an extremely cloudy tropical forest region. The CLASlite approach provided highly automated mapping of tropical forest cover, deforestation and degradation from Landsat satellite imagery. Critically, the fractional cover of forest photosynthetic vegetation, non-photosynthetic vegetation, and bare substrates calculated by CLASlite provided scene-invariant quantities for forest cover, allowing for systematic mosaicking of incomplete satellite data coverage. A synthesized satellite-based data set of forest cover was thereby created, reducing image incompleteness caused by clouds, shadows or sensor errors. This approach can readily be implemented by single operators with highly constrained budgets. We test this framework on tropical forests of the Colombian Pacific Coast (Chocó) – one of the cloudiest regions on Earth, with successful comparison to the Colombian government’s deforestation map and a global deforestation map. PMID:25678933

  12. Critical Rare Earths, National Security, and U.S.-China Interactions: A Portfolio Approach to Dysprosium Policy Design

    DTIC Science & Technology

    2015-01-01

    by the graduate fellow’s faculty committee. C O R P O R A T I O N Dissertation Critical Rare Earths, National Security, and U.S.-China Interactions A...Portfolio Approach to Dysprosium Policy Design David L. An Dissertation Critical Rare Earths, National Security, and U.S.-China Interactions A...Permanent Magnet ................................................ xxiv Dysprosium, the Most Critical Rare Earth

  13. National Heart, Lung, and Blood Institute and the translation of cardiovascular discoveries into therapeutic approaches.

    PubMed

    Galis, Zorina S; Black, Jodi B; Skarlatos, Sonia I

    2013-04-26

    The molecular causes of ≈4000 medical conditions have been described, yet only 5% have associated therapies. For decades, the average time for drug development through approval has taken 10 to 20 years. In recent years, the serious challenges that confront the private sector have made it difficult to capitalize on new opportunities presented by advances in genomics and cellular therapies. Current trends are disturbing. Pharmaceutical companies are reducing their investments in research, and biotechnology companies are struggling to obtain venture funds. To support early-stage translation of the discoveries in basic science, the National Institutes of Health and the National Heart, Lung, and Blood Institute have developed new approaches to facilitating the translation of basic discoveries into clinical applications and will continue to develop a variety of programs that create teams of academic investigators and industry partners. The goal of these programs is to maximize the public benefit of investment of taxpayer dollars in biomedical research and to lessen the risk required for industry partners to make substantial investments. This article highlights several examples of National Heart, Lung, and Blood Institute-initiated translational programs and National Institutes of Health translational resources designed to catalyze and enable the earliest stages of the biomedical product development process. The translation of latest discoveries into therapeutic approaches depends on continued federal funding to enhance the early stages of the product development process and to stimulate and catalyze partnerships between academia, industry, and other sources of capital.

  14. Proceedings of the sudden oak death fifth science symposium

    Treesearch

    Susan J. Frankel; John T. Kliejunas; Katharine M. Palmieri; Janice M. Alexander

    2013-01-01

    The Proceedings of the Sudden Oak Death Fifth Science Symposium provides an update on research to address sudden oak death, caused by the exotic, quarantine pathogen, Phytophthora ramorum. Over 60 submissions present national and international investigations covering pathogen biology, biosecurity, genetics, monitoring, fire ecology, and diagnostics...

  15. A Technical Report To The Secretary Of Transportation On A National Approach To Augmented Gps Services

    DOT National Transportation Integrated Search

    1994-12-01

    THIS REPORT DOCUMENTS THE DEVELOPMENT OF RECOMMENDATIONS FOR A NATIONAL APPROACH TO AUGMENTED GLOBAL POSITIONING SYSTEM (GPS) SERVICES. THE INSTITUTE FOR TELECOMMUNICATION SCIENCES LED A STUDY TEAM THAT INCLUDED THE U.S. ARMY TOPOGRAPHIC ENGINEERING ...

  16. Canadian experiences with avian influenza: a look at regional disease control--past, present, and future.

    PubMed

    Vaillancourt, J-P

    2009-04-01

    Over the past 5 yr, the poultry industry in Canada has had a few H5 or H7 avian influenza (AI) epidemics. An analysis of these outbreaks by government officials highlighted the need to establish a better partnership between those responsible for controlling the disease and public health officials responsible for protecting the public and those participating in eradication efforts. These officials also agreed that compensations had to be reviewed, that national biosecurity standards needed to be established to better prevent AI, that a national mortality disposal plan was needed, and finally that the current emergency disease management protocols had to be reviewed. Industry representatives stressed the need for early detection and reporting; for more effective tools for decision making, including using local expertise for trace-back activities and quick interventions; for better communications within industry, but mainly between industry and governmental authorities at the federal, provincial, and municipal levels; and finally, for better planning to minimize the impact of eradication efforts on poultry production and for the recovery following the epidemic. These observations triggered a series of initiatives. A National Office of Animal Biosecurity was created by federal authorities, with the mandate to establish national biosecurity standards. A Canadian Animal Health Surveillance Network was also put in place to improve the capacity of early detection of the disease and to increase the surge capacity of the Canadian laboratory system. Wildlife and commercial poultry AI surveillance programs have also been put in place. Provincial poultry grower organizations have established AI control and eradication plans that are increasing their ability to intervene early and to assist government authorities once AI is confirmed in the field. This includes the creation of industry incident command centers with emphasis on confidentiality agreements between government and

  17. Special Forest Products on the Green Mountain and Finger Lakes National Forests: a research-based approach to management

    Treesearch

    Marla R. Emery; Clare Ginger

    2014-01-01

    Special forest products (SFPs) are gathered from more than 200 vascular and fungal species on the Green Mountain National Forest (GMNF) and Finger Lakes National Forest (FLNF). This report documents those SFPs and proposes an approach to managing them in the context of legislation directing the U.S. Forest Service to institute a program of active SFP management. Based...

  18. Characterization of backyard poultry production systems and disease risk in the central zone of Chile.

    PubMed

    Hamilton-West, C; Rojas, H; Pinto, J; Orozco, J; Hervé-Claude, L P; Urcelay, S

    2012-08-01

    Backyard poultry production systems (BPS) are an important and widespread form of poultry production. There is a common perception that biosecurity standards in BPS are generally poor and BPS are usually associated with animal diseases and zoonoses. In this study BPS were identified in the vicinity of six wetlands, having these a higher risk of presenting and introducing avian diseases such as HPAI and Newcastle disease, as defined by the national veterinary services, in to Chile's main poultry production area. BPS were characterized through a field questionnaire and the main areas covered by the survey were BPS structure, biosecurity and value chain. The BPS identified in this study share most characteristics on biosecurity, poultry management and product commercialization, but it was possible to identify a certain degree of variation within and among the study sites. BPS in Chile are similar to those in other regions, with a relatively small flock size (average 37 birds), a low level of biosecurity measures and lack of poultry disease management. Management findings include that most farmers used mixed/partial confinement, with low or no biosecurity and disease control measures in place. Eggs were the main output and were used mainly for home consumption or sale at local markets. Sick birds' treatment with drugs approved for other species or for human use could represent a risk to human health, owing to the possible presence of drug residues in poultry products. Despite the different structures of the poultry sector worldwide, BPS can play a major role in disease maintenance and spread because its management conditions characteristics and the lack of animal health services adapted to these production systems. This should be an alert message to the veterinary authorities to improve coverage of veterinary assistance and surveillance activities in backyard poultry production. Copyright © 2011 Elsevier Ltd. All rights reserved.

  19. Biopreparedness in the Age of Genetically Engineered Pathogens and Open Access Science: An Urgent Need for a Paradigm Shift.

    PubMed

    MacIntyre, C Raina

    2015-09-01

    Our systems, thinking, training, legislation, and policies are lagging far behind momentous changes in science, and leaving us vulnerable in biosecurity. Synthetic viruses and genetic engineering of pathogens are a reality, with a rapid acceleration of dual-use science. The public availability of methods for dual-use genetic engineering, coupled with the insider threat, poses an unprecedented risk for biosecurity. Case studies including the 1984 Rajneesh salmonella bioterrorism attack and the controversy over engineered transmissible H5N1 influenza are analyzed. Simple probability analysis shows that the risks of dual-use research are likely to outweigh potential benefits, yet this type of analysis has not been done to date. Many bioterrorism agents may also occur naturally. Distinguishing natural from unnatural epidemics is far more difficult than other types of terrorism. Public health systems do not have mechanisms for routinely considering bioterrorism, and an organizational culture that is reluctant to consider it. A collaborative model for flagging aberrant outbreak patterns and referral from the health to security sectors is proposed. Vulnerabilities in current approaches to biosecurity need to be reviewed and strengthened collaboratively by all stakeholders. New systems, legislation, collaborative operational models, and ways of thinking are required to effectively address the threat to global biosecurity. Reprint & Copyright © 2015 Association of Military Surgeons of the U.S.

  20. Predicting costs of alien species surveillance across varying transportation networks

    Treesearch

    Laura Blackburn; Rebecca Epanchin-Niell; Alexandra Thompson; Andrew Liebhold; Jacqueline Beggs

    2017-01-01

    Efforts to detect and eradicate invading populations before they establish are a critical component of national biosecurity programmes. An essential element for maximizing the efficiency of these efforts is the balancing of expenditures on surveillance (e.g. trapping) versus treatment (e.g. eradication). Identifying the optimal allocation of resources towards...

  1. 76 FR 5391 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-31

    ... Activities, Office of Science Policy, Office of the Director Amended Notice of Meeting Notice is hereby given of a change in the meeting of the National Science Advisory Board for Biosecurity (NSABB), February... Federal Advisory Committee Policy. [FR Doc. 2011-2022 Filed 1-28-11; 8:45 am] BILLING CODE 4140-01-P ...

  2. 77 FR 66624 - Office of Biotechnology Activities, Office of Science Policy, Office of the Director; Notice of...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-06

    ... Activities, Office of Science Policy, Office of the Director; Notice of Meeting Pursuant to section 10(a) of... following meeting. Name of Committee: National Science Advisory Board for Biosecurity. Date: November 27... Federal Advisory Committee Policy. [FR Doc. 2012-26994 Filed 11-5-12; 8:45 am] BILLING CODE 4140-01-P ...

  3. Assessing Biosecurity Risks for the Introduction and Spread of Diseases Among Commercial Sheep Properties in New South Wales, Australia, Using Foot-and-Mouth Disease as a Case Study.

    PubMed

    Fountain, Jake; Woodgate, Robert; Rast, Luzia; Hernández-Jover, Marta

    2018-01-01

    Sheep production systems are a major industry in Australia, with a gross value of roughly $4.66 billion; 87.3% of which is attributable to export markets. Exotic diseases such as foot-and-mouth disease (FMD) are a potential threat to the viability of Australia's export market. Previous outbreaks of FMD in developed countries, and challenges in the management of onshore biosecurity, signify the importance of on-farm biosecurity in controlling disease transmission. This study aims to investigate the risk of disease introduction and spread among New South Wales (NSW) sheep properties using FMD as a case study and draw recommendation for the industry. Exposure and partial consequence assessments, using scenario trees and Monte Carlo stochastic modeling, were conducted to identify pathways of introduction and spread and calculate the probabilities of these pathways occurring. Input parameters were estimated from the data obtained during qualitative interviews with producers and scientific literature. According to the reported practices of sheep producers and assuming each pathway was carrying the FMD virus, the exposure assessment estimates the median (5-95%) probability of FMD exposure of sheep on a naive property to be 0.619 (0.541-0.698), 0.151 (0.085-0.239), 0.235 (0.153-0.324), and 0.710 (0.619-0.791) for introduction through new stock, wildlife, carriers (humans, dogs, and vehicles), and neighbors, respectively. The spread assessment estimated the median probability of FMD spreading from an infected sheep property to neighboring enterprises to be 0.603 (0.504-0.698). A similar probability was estimated for spread via wildlife (0.523; 0.404-0.638); and a lower spread probability was estimated for carriers (0.315; 0.171-0.527), sheep movement (0.285; 0.161-0.462), and dead stock (0.168; 0.070-0.312). The sensitivity analysis revealed that the introduction of an FMD-infected sheep was more influential for exposure via new stock than isolation practices. Sharing

  4. Assessing Biosecurity Risks for the Introduction and Spread of Diseases Among Commercial Sheep Properties in New South Wales, Australia, Using Foot-and-Mouth Disease as a Case Study

    PubMed Central

    Fountain, Jake; Woodgate, Robert; Rast, Luzia; Hernández-Jover, Marta

    2018-01-01

    Sheep production systems are a major industry in Australia, with a gross value of roughly $4.66 billion; 87.3% of which is attributable to export markets. Exotic diseases such as foot-and-mouth disease (FMD) are a potential threat to the viability of Australia’s export market. Previous outbreaks of FMD in developed countries, and challenges in the management of onshore biosecurity, signify the importance of on-farm biosecurity in controlling disease transmission. This study aims to investigate the risk of disease introduction and spread among New South Wales (NSW) sheep properties using FMD as a case study and draw recommendation for the industry. Exposure and partial consequence assessments, using scenario trees and Monte Carlo stochastic modeling, were conducted to identify pathways of introduction and spread and calculate the probabilities of these pathways occurring. Input parameters were estimated from the data obtained during qualitative interviews with producers and scientific literature. According to the reported practices of sheep producers and assuming each pathway was carrying the FMD virus, the exposure assessment estimates the median (5–95%) probability of FMD exposure of sheep on a naive property to be 0.619 (0.541–0.698), 0.151 (0.085–0.239), 0.235 (0.153–0.324), and 0.710 (0.619–0.791) for introduction through new stock, wildlife, carriers (humans, dogs, and vehicles), and neighbors, respectively. The spread assessment estimated the median probability of FMD spreading from an infected sheep property to neighboring enterprises to be 0.603 (0.504–0.698). A similar probability was estimated for spread via wildlife (0.523; 0.404–0.638); and a lower spread probability was estimated for carriers (0.315; 0.171–0.527), sheep movement (0.285; 0.161–0.462), and dead stock (0.168; 0.070–0.312). The sensitivity analysis revealed that the introduction of an FMD-infected sheep was more influential for exposure via new stock than isolation

  5. Nationally Consistent Environmental Justice Screening Approaches

    EPA Pesticide Factsheets

    This report discusses screening approaches through the lens of the Agency's Environmental Justice Strategic Enforcement Tool (EJSEAT), in particular, and how such approaches might better identify areas of concern.

  6. Measuring the Immeasurable: An Approach to Assessing the Effectiveness of Engineering Civic Assistance Projects Towards Achieving National Security Objectives

    DTIC Science & Technology

    2015-06-12

    MEASURING THE IMMEASURABLE: AN APPROACH TO ASSESSING THE EFFECTIVENESS OF ENGINEERING CIVIC ASSISTANCE PROJECTS TOWARDS ACHIEVING...SUBTITLE Measuring the Immeasurable: An Approach to Assessing the Effectiveness of Engineering Civic Assistance Projects Towards Achieving National...increasing reliance on Humanitarian and Civic Assistance (HCA), specifically engineering civic assistance projects (ENCAPs), as a way to shape the

  7. Transfrontal and Transsphenoidal Approaches to Pediatric Craniopharyngioma: A National Perspective.

    PubMed

    Lin, Yimo; Hansen, Daniel; Sayama, Christina M; Pan, I-Wen; Lam, Sandi

    2017-01-01

    This study compared transsphenoidal (TS) and transfrontal (TF) approaches to craniopharyngioma utilizing a national database. The Kids' Inpatient Database (2003, 2006, and 2009) was surveyed for patients with a diagnosis of craniopharyngioma who underwent a subset of surgical interventions to compare TS and TF surgery. Demographics, hospital variables, and complications/comorbidities were analyzed with multivariate regression. 314 admissions (TS = 104, TF = 210) were identified. The mean age was 14.8 (TS) versus 9.8 (TF) years (p < 0.001). The mean number of diagnoses was 4.6 (TS) versus 6.2 (TF) (p < 0.001). Diabetes insipidus was associated with 38% (TS) and 69% (TF). Cerebrospinal fluid (CSF) leak affected 19% TS and 4% TF resections. Other complications and comorbidities included postoperative stroke (2% TS vs. 5% TF), panhypopituitarism (5 vs. 8%), death (0 vs. 1%), cranial nerve deficits (1 vs. 6%), thrombotic events (7 vs. 17%), and seizures (0 vs. 12%). 98% of patients were discharged home after a mean 6-day length of stay (LOS) after TS, whereas 90% of TF patients had a LOS of 12 days. TS cases were more likely to be privately insured (68%) and from higher income brackets (61%) than TF ones (56 and 2%, respectively) (p < 0.05). In multivariate regression models adjusting for age, sex, race, number of diagnoses, surgical approach, hospital volume, and insurance type, the TS approach was associated with an increased incidence of CSF leak (OR 10, p < 0.001). More documented diagnoses (OR 16-60, p < 0.01) and TF approach (OR 2.6, p < 0.01) were associated with an increased incidence of other complications and comorbidities. Age younger than 10 (β-coefficient 2.3, p = 0.01), more diagnoses (β-coefficient 1.2, p < 0.001), and TF approach (β- coefficient 3.0, p < 0.01) were associated with increased LOS. A higher number of diagnoses were associated with nonhome discharge destinations (β-coefficient 1.29, p < 0.001). TS surgery was associated with an increased

  8. Integrative Analysis of the Physical Transport Network into Australia.

    PubMed

    Cope, Robert C; Ross, Joshua V; Wittmann, Talia A; Prowse, Thomas A A; Cassey, Phillip

    2016-01-01

    Effective biosecurity is necessary to protect nations and their citizens from a variety of threats, including emerging infectious diseases, agricultural or environmental pests and pathogens, and illegal wildlife trade. The physical pathways by which these threats are transported internationally, predominantly shipping and air traffic, have undergone significant growth and changes in spatial distributions in recent decades. An understanding of the specific pathways and donor-traffic hotspots created by this integrated physical transport network is vital for the development of effective biosecurity strategies into the future. In this study, we analysed the physical transport network into Australia over the period 1999-2012. Seaborne and air traffic were weighted to calculate a "weighted cumulative impact" score for each source region worldwide, each year. High risk source regions, and those source regions that underwent substantial changes in risk over the study period, were determined. An overall risk ranking was calculated by integrating across all possible weighting combinations. The source regions having greatest overall physical connectedness with Australia were Singapore, which is a global transport hub, and the North Island of New Zealand, a close regional trading partner with Australia. Both those regions with large amounts of traffic across multiple vectors (e.g., Hong Kong), and those with high levels of traffic of only one type (e.g., Bali, Indonesia with respect to passenger flights), were represented among high risk source regions. These data provide a baseline model for the transport of individuals and commodities against which the effectiveness of biosecurity controls may be assessed, and are a valuable tool in the development of future biosecurity policy.

  9. Emerging Technologies: Biosecurity and Consequence Management Implications

    NASA Astrophysics Data System (ADS)

    Perkins, Dana; Nordmann, Brian

    The natural outbreaks of disease and pandemics are transnational threats that create international challenges when detection and containment are not timely due to scarce human and material resources. Whether the cause of those outbreaks is natural or intentional in origin, the main goal of consequence management operations is to save lives. The consequence management process is a continuum of inter-connected phases such as planning, preparation, response, and recovery. The rapid advances of life sciences and the emergence of dual-use technologies such as synthetic biology and nanotechnology pose additional challenges in terms of planning for the unknown potential threats whether they may be synthetic microorganisms with unpredictable dissemination patterns or nanoscale-manipulated biological agents evading current detection capabilities. The US National Strategy for Countering Biological Threats is emphasizing prevention while continuing to support the national preparedness goals and response/recovery capabilities. The recent policies, guidelines, and recommendations on overhauling the biological risk management in the United States are a proactive stance to a rapidly changing global environment. They include optimization of the current oversight frameworks and active engagement of the industry and academia in order to reduce the risk that individuals with ill intent may exploit the commercial application of nucleic acid synthesis technology to access genetic material derived from or by encoding Biological Select Agents or Toxins. We are also actively seeking to increase our knowledge of health effects of various types of nanomaterials, and how to assess, control, and prevent harmful exposure, taking into consideration the numerous gaps that currently exist with regard to the distinct behavior of nanoparticles compared to the same chemical or material at "macro-scale". Fundamentally, a biological incident, whether it is of natural, accidental, or deliberate origin

  10. Converging approaches to understanding early onset familial Alzheimer disease: A First Nation study

    PubMed Central

    Cabrera, Laura Y; Beattie, B Lynn; Dwosh, Emily; Illes, Judy

    2015-01-01

    Objectives: In 2007, a novel pathogenic genetic mutation associated with early onset familial Alzheimer disease was identified in a large First Nation family living in communities across British Columbia, Canada. Building on a community-based participatory study with members of the Nation, we sought to explore the impact and interplay of medicalization with the Nation’s knowledge and approaches to wellness in relation to early onset familial Alzheimer disease. Methods: We performed a secondary content analysis of focus group discussions and interviews with 48 members of the Nation between 2012 and 2013. The analysis focused specifically on geneticization, medicalization, and traditional knowledge of early onset familial Alzheimer disease, as these themes were prominent in the primary analysis. Results: We found that while biomedical explanations of disease permeate the knowledge and understanding of early onset familial Alzheimer disease, traditional concepts about wellness are upheld simultaneously. Conclusion: The analysis brings the theoretical framework of “two-eyed seeing” to the case of early onset familial Alzheimer disease for which the contributions of different ways of knowing are embraced, and in which traditional and western ways complement each other on the path of maintaining wellness in the face of progressive neurologic disease. PMID:27092264

  11. A new approach to generating research-quality phenology data: The USA National Phenology Monitoring System

    NASA Astrophysics Data System (ADS)

    Denny, E. G.; Miller-Rushing, A. J.; Haggerty, B. P.; Wilson, B. E.

    2009-12-01

    The USA National Phenology Network has recently initiated a national effort to encourage people at different levels of expertise—from backyard naturalists to professional scientists—to observe phenological events and contribute to a national database that will be used to greatly improve our understanding of spatio-temporal variation in phenology and associated phenological responses to climate change. Traditional phenological observation protocols identify specific single dates at which individual phenological events are observed, but the scientific usefulness of long-term phenological observations can be improved with a more carefully structured protocol. At the USA-NPN we have developed a new approach that directs observers to record each day that they observe an individual plant, and to assess and report the state of specific life stages (or phenophases) as occurring or not occurring on that plant for each observation date. Evaluation is phrased in terms of simple, easy-to-understand, questions (e.g. “Do you see open flowers?”), which makes it very appropriate for a broad audience. From this method, a rich dataset of phenological metrics can be extracted, including the duration of a phenophase (e.g. open flowers), the beginning and end points of a phenophase (e.g. traditional phenological events such as first flower and last flower), multiple distinct occurrences of phenophases within a single growing season (e.g multiple flowering events, common in drought-prone regions), as well as quantification of sampling frequency and observational uncertainties. The system also includes a mechanism for translation of phenophase start and end points into standard traditional phenological events to facilitate comparison of contemporary data collected with this new “phenophase status” monitoring approach to historical datasets collected with the “phenological event” monitoring approach. These features greatly enhance the utility of the resulting data for

  12. A new approach to generating research-quality phenology data: The USA National Phenology Monitoring System

    NASA Astrophysics Data System (ADS)

    Denny, Ellen; Miller-Rushing, Abraham; Haggerty, Brian; Wilson, Bruce; Weltzin, Jake

    2010-05-01

    The USA National Phenology Network (www.usanpn.org) has recently initiated a national effort to encourage people at different levels of expertise—from backyard naturalists to professional scientists—to observe phenological events and contribute to a national database that will be used to greatly improve our understanding of spatio-temporal variation in phenology and associated phenological responses to climate change. Traditional phenological observation protocols identify specific single dates at which individual phenological events are observed, but the scientific usefulness of long-term phenological observations can be improved with a more carefully structured protocol. At the USA-NPN we have developed a new approach that directs observers to record each day that they observe an individual plant, and to assess and report the state of specific life stages (or phenophases) as occurring or not occurring on that plant for each observation date. Evaluation is phrased in terms of simple, easy-to-understand, questions (e.g. "Do you see open flowers?"), which makes it very appropriate for a broad audience. From this method, a rich dataset of phenological metrics can be extracted, including the duration of a phenophase (e.g. open flowers), the beginning and end points of a phenophase (e.g. traditional phenological events such as first flower and last flower), multiple distinct occurrences of phenophases within a single growing season (e.g multiple flowering events, common in drought-prone regions), as well as quantification of sampling frequency and observational uncertainties. The system also includes a mechanism for translation of phenophase start and end points into standard traditional phenological events to facilitate comparison of contemporary data collected with this new "phenophase status" monitoring approach to historical datasets collected with the "phenological event" monitoring approach. These features greatly enhance the utility of the resulting data for

  13. Characterization of influenza a outbreaks in Minnesota swine herds and measures taken to reduce the risk of zoonotic transmission.

    PubMed

    Beaudoin, A; Johnson, S; Davies, P; Bender, J; Gramer, M

    2012-03-01

    Influenza A virus infections commonly cause respiratory disease in swine and can be transmitted between people and pigs, with potentially novel strains introduced into herds and spilling back into the human population. The goals of this study were to characterize influenza infections in Minnesota pigs and assess biosecurity measures used by swine workers. Veterinarians submitting influenza-positive swine samples to the University of Minnesota Veterinary Diagnostic Laboratory between October 2007 and April 2009 were surveyed regarding disease-related information and biosecurity procedures at each farm. Influenza-positive samples were submitted year-round, peaking in spring and fall. H1N1 was the most commonly detected subtype (56%), followed by H3N2 (14%) and H1N2 (12%). Most positive submissions were associated with illness in growing pigs (median age 8.8 weeks, IQR 5-15). Median morbidity and mortality were 25% (IQR 10-48) and 2% (IQR 0.5-3.5), respectively. Vaccination of sows and growing pigs was conducted at 71% and 7.9% of the swine farms, respectively. Specialized footwear was reported as the most common form of protective equipment used by workers. Employee vaccination for seasonal influenza was 19%. The sow vaccination rate in this study is consistent with national data, although growing pig vaccination is lower than the national average. Seasonal and age trends identified here may provide diagnostic guidance when growing pigs experience respiratory disease. Inconsistent use of protective equipment and employee vaccination at swine farms indicates the need for further discussion and research of approaches to minimize interspecies influenza transmission on swine farms. © 2011 Blackwell Verlag GmbH.

  14. Novel Vaccine Approach Achieves “Functional Cure” of AIDS Virus in Monkeys | Frederick National Laboratory for Cancer Research

    Cancer.gov

    Scientists at the Oregon Health & Science University and the AIDS and Cancer Virus Program of the Frederick National Laboratory for Cancer Research have used a novel vaccine approach to achieve a “functional cure” and apparent eradication of infe

  15. Mitochondrial DNA and trade data support multiple origins of Helicoverpa armigera (Lepidoptera, Noctuidae) in Brazil

    PubMed Central

    Tay, Wee Tek; Walsh, Thomas K.; Downes, Sharon; Anderson, Craig; Jermiin, Lars S.; Wong, Thomas K. F.; Piper, Melissa C.; Chang, Ester Silva; Macedo, Isabella Barony; Czepak, Cecilia; Behere, Gajanan T.; Silvie, Pierre; Soria, Miguel F.; Frayssinet, Marie; Gordon, Karl H. J.

    2017-01-01

    The Old World bollworm Helicoverpa armigera is now established in Brazil but efforts to identify incursion origin(s) and pathway(s) have met with limited success due to the patchiness of available data. Using international agricultural/horticultural commodity trade data and mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origins and incursion pathways into Brazil. We detected 20 mtDNA haplotypes from six Brazilian states, eight of which were new to our 97 global COI-Cyt b haplotype database. Direct sequence matches indicated five Brazilian haplotypes had Asian, African, and European origins. We identified 45 parsimoniously informative sites and multiple substitutions per site within the concatenated (945 bp) nucleotide dataset, implying that probabilistic phylogenetic analysis methods are needed. High diversity and signatures of uniquely shared haplotypes with diverse localities combined with the trade data suggested multiple incursions and introduction origins in Brazil. Increasing agricultural/horticultural trade activities between the Old and New Worlds represents a significant biosecurity risk factor. Identifying pest origins will enable resistance profiling that reflects countries of origin to be included when developing a resistance management strategy, while identifying incursion pathways will improve biosecurity protocols and risk analysis at biosecurity hotspots including national ports. PMID:28350004

  16. Mitochondrial DNA and trade data support multiple origins of Helicoverpa armigera (Lepidoptera, Noctuidae) in Brazil.

    PubMed

    Tay, Wee Tek; Walsh, Thomas K; Downes, Sharon; Anderson, Craig; Jermiin, Lars S; Wong, Thomas K F; Piper, Melissa C; Chang, Ester Silva; Macedo, Isabella Barony; Czepak, Cecilia; Behere, Gajanan T; Silvie, Pierre; Soria, Miguel F; Frayssinet, Marie; Gordon, Karl H J

    2017-03-28

    The Old World bollworm Helicoverpa armigera is now established in Brazil but efforts to identify incursion origin(s) and pathway(s) have met with limited success due to the patchiness of available data. Using international agricultural/horticultural commodity trade data and mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origins and incursion pathways into Brazil. We detected 20 mtDNA haplotypes from six Brazilian states, eight of which were new to our 97 global COI-Cyt b haplotype database. Direct sequence matches indicated five Brazilian haplotypes had Asian, African, and European origins. We identified 45 parsimoniously informative sites and multiple substitutions per site within the concatenated (945 bp) nucleotide dataset, implying that probabilistic phylogenetic analysis methods are needed. High diversity and signatures of uniquely shared haplotypes with diverse localities combined with the trade data suggested multiple incursions and introduction origins in Brazil. Increasing agricultural/horticultural trade activities between the Old and New Worlds represents a significant biosecurity risk factor. Identifying pest origins will enable resistance profiling that reflects countries of origin to be included when developing a resistance management strategy, while identifying incursion pathways will improve biosecurity protocols and risk analysis at biosecurity hotspots including national ports.

  17. Mitochondrial DNA and trade data support multiple origins of Helicoverpa armigera (Lepidoptera, Noctuidae) in Brazil

    NASA Astrophysics Data System (ADS)

    Tay, Wee Tek; Walsh, Thomas K.; Downes, Sharon; Anderson, Craig; Jermiin, Lars S.; Wong, Thomas K. F.; Piper, Melissa C.; Chang, Ester Silva; Macedo, Isabella Barony; Czepak, Cecilia; Behere, Gajanan T.; Silvie, Pierre; Soria, Miguel F.; Frayssinet, Marie; Gordon, Karl H. J.

    2017-03-01

    The Old World bollworm Helicoverpa armigera is now established in Brazil but efforts to identify incursion origin(s) and pathway(s) have met with limited success due to the patchiness of available data. Using international agricultural/horticultural commodity trade data and mitochondrial DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origins and incursion pathways into Brazil. We detected 20 mtDNA haplotypes from six Brazilian states, eight of which were new to our 97 global COI-Cyt b haplotype database. Direct sequence matches indicated five Brazilian haplotypes had Asian, African, and European origins. We identified 45 parsimoniously informative sites and multiple substitutions per site within the concatenated (945 bp) nucleotide dataset, implying that probabilistic phylogenetic analysis methods are needed. High diversity and signatures of uniquely shared haplotypes with diverse localities combined with the trade data suggested multiple incursions and introduction origins in Brazil. Increasing agricultural/horticultural trade activities between the Old and New Worlds represents a significant biosecurity risk factor. Identifying pest origins will enable resistance profiling that reflects countries of origin to be included when developing a resistance management strategy, while identifying incursion pathways will improve biosecurity protocols and risk analysis at biosecurity hotspots including national ports.

  18. Toward the improvement of trail classification in national parks using the recreation opportunity spectrum approach.

    PubMed

    Oishi, Yoshitaka

    2013-06-01

    Trail settings in national parks are essential management tools for improving both ecological conservation efforts and the quality of visitor experiences. This study proposes a plan for the appropriate maintenance of trails in Chubusangaku National Park, Japan, based on the recreation opportunity spectrum (ROS) approach. First, we distributed 452 questionnaires to determine park visitors' preferences for setting a trail (response rate = 68 %). Respondents' preferences were then evaluated according to the following seven parameters: access, remoteness, naturalness, facilities and site management, social encounters, visitor impact, and visitor management. Using nonmetric multidimensional scaling and cluster analysis, the visitors were classified into seven groups. Last, we classified the actual trails according to the visitor questionnaire criteria to examine the discrepancy between visitors' preferences and actual trail settings. The actual trail classification indicated that while most developed trails were located in accessible places, primitive trails were located in remote areas. However, interestingly, two visitor groups seemed to prefer a well-conserved natural environment and, simultaneously, easily accessible trails. This finding does not correspond to a premise of the ROS approach, which supposes that primitive trails should be located in remote areas without ready access. Based on this study's results, we propose that creating trails, which afford visitors the opportunity to experience a well-conserved natural environment in accessible areas is a useful means to provide visitors with diverse recreation opportunities. The process of data collection and analysis in this study can be one approach to produce ROS maps for providing visitors with recreational opportunities of greater diversity and higher quality.

  19. Integrative Analysis of the Physical Transport Network into Australia

    PubMed Central

    Cope, Robert C.; Ross, Joshua V.; Wittmann, Talia A.; Prowse, Thomas A. A.; Cassey, Phillip

    2016-01-01

    Effective biosecurity is necessary to protect nations and their citizens from a variety of threats, including emerging infectious diseases, agricultural or environmental pests and pathogens, and illegal wildlife trade. The physical pathways by which these threats are transported internationally, predominantly shipping and air traffic, have undergone significant growth and changes in spatial distributions in recent decades. An understanding of the specific pathways and donor-traffic hotspots created by this integrated physical transport network is vital for the development of effective biosecurity strategies into the future. In this study, we analysed the physical transport network into Australia over the period 1999–2012. Seaborne and air traffic were weighted to calculate a “weighted cumulative impact” score for each source region worldwide, each year. High risk source regions, and those source regions that underwent substantial changes in risk over the study period, were determined. An overall risk ranking was calculated by integrating across all possible weighting combinations. The source regions having greatest overall physical connectedness with Australia were Singapore, which is a global transport hub, and the North Island of New Zealand, a close regional trading partner with Australia. Both those regions with large amounts of traffic across multiple vectors (e.g., Hong Kong), and those with high levels of traffic of only one type (e.g., Bali, Indonesia with respect to passenger flights), were represented among high risk source regions. These data provide a baseline model for the transport of individuals and commodities against which the effectiveness of biosecurity controls may be assessed, and are a valuable tool in the development of future biosecurity policy. PMID:26881782

  20. Online applied dual-use biosecurity education: a case study from the University of Bradford.

    PubMed

    Bollaert, Cathy; Whitby, Simon

    2012-01-01

    Reflecting a consensus that emerged at the 2008 Meeting of States Parties of the Biological Weapons Convention on the importance of ensuring that those working in the biological sciences are aware of their obligations under the Convention and relevant national legislation and guidelines; and in regard to the consensus on the importance of awareness raising and education and training programmes, and of the role that these can play in assisting in the implementation of the Convention, this paper highlights how novel online e-learning approaches can efficiently and effectively be deployed in building a sustainable worldwide capability in this much neglected area of education and training. It provides examples of the development and evolution of education and training resources, notes the importance of standing agenda items for the intersessional process of the BWC between the Seventh and Eight Review Conferences and the range of opportunities that therefore arise for States Party and civil society collaboration in building capacity and achieving sustainability in this area.

  1. A formalized approach to making effective natural resource management decisions for Alaska National Parks

    USGS Publications Warehouse

    MacCluskie, Margaret C.; Romito, Angela; Peterson, James T.; Lawler, James P.

    2015-01-01

    A fundamental goal of the National Park Service (NPS) is the long-term protection and management of resources in the National Park System. Reaching this goal requires multiple approaches, including the conservation of essential habitats and the identification and elimination of potential threats to biota and habitats. To accomplish these goals, the NPS has implemented the Alaska Region Vital Signs Inventory and Monitoring (I&M) Program to monitor key biological, chemical, and physical components of ecosystems at more than 270 national parks. The Alaska Region has four networks—Arctic, Central, Southeast, and Southwest. By monitoring vital signs over large spatial and temporal scales, park managers are provided with information on the status and trajectory of park resources as well as a greater understanding and insight into the ecosystem dynamics. While detecting and quantifying change is important to conservation efforts, to be useful for formulating remedial actions, monitoring data must explicitly relate to management objectives and be collected in such a manner as to resolve key uncertainties about the dynamics of the system (Nichols and Williams 2006). Formal decision making frameworks (versus more traditional processes described below) allow for the explicit integration of monitoring data into decision making processes to improve the understanding of system dynamics, thereby improving future decisions (Williams 2011).

  2. Biosecurity: Addressing the Threats of Bioterrorism and Infectious Diseases

    DTIC Science & Technology

    2010-03-22

    threats. Discussion: Biological threats can be divided into the intentional use of biological weapons as a form of terrorist attack and the natural...level, the Biological Weapon Convention (BWC) and World Health Organization (WHO) continue to act as key platforms to synchronize efforts to counter...outbreak. 5 2.1 BIOTERRORISM According to the United Nations, " Biological weapons are devices which disseminate disease-causing organisms or poisons

  3. National Health Guidelines in I.R of Iran, an Innovative Approach for Developing Countries

    PubMed Central

    Esmaeil Akbari, Mohammad; Mohammadi, Gohar; Vosoogh-Moghaddam, Abbas; Rabanikhah, Fahimeh; Javadi, Hamideh; Rostami-Gooran, Narges; Safaei, Asal; Akbari, Atieh

    2015-01-01

    Background Guidelines have produced and used in complex environment of health care system with its ethical, economical, legal and other aspects; that should be taken into account in any country. Modifying the format and content of guidelines might facilitate their usage and lead to improved quality of care and cost containment. We have produced this tool for explained above purpose. Methods A coordinating national team has settled at the office of minster of health and medical education, supported by a guideline review committee. An innovative and appropriate approach for adapting national health guidelines has consisted of eight steps, have defined For preparing the draft of each guideline a technical team which, including main author, her/his co-workers have nominated. The authors of each topic have systematically searched databases of the proposed Twenty-two International Sites, and then have selected at least five sources of them that were more relevant. The final recommendations have proposed by agreement of technical team and Guideline Review Committee. Results In less than 5 months, more than 500 authors in whole country have selected to prepare guidelines and, approximately 150 guidelines have provided in three volumes of the published and distributed book. Each guideline had a national ID number, constant forever; all topics should be reviewed every 3-5 years. Conclusion National health guideline(s) would be essential means for policy making in health system and increased the cost containment and quality of care. Ministry of Health and Medical Education should provide and distribute the guidelines based on its accountability to legal responsibility. PMID:25960845

  4. National health guidelines in I.R of iran, an innovative approach for developing countries.

    PubMed

    Esmaeil Akbari, Mohammad; Mohammadi, Gohar; Vosoogh-Moghaddam, Abbas; Rabanikhah, Fahimeh; Javadi, Hamideh; Rostami-Gooran, Narges; Safaei, Asal; Akbari, Atieh

    2015-01-01

    Guidelines have produced and used in complex environment of health care system with its ethical, economical, legal and other aspects; that should be taken into account in any country. Modifying the format and content of guidelines might facilitate their usage and lead to improved quality of care and cost containment. We have produced this tool for explained above purpose. A coordinating national team has settled at the office of minster of health and medical education, supported by a guideline review committee. An innovative and appropriate approach for adapting national health guidelines has consisted of eight steps, have defined For preparing the draft of each guideline a technical team which, including main author, her/his co-workers have nominated. The authors of each topic have systematically searched databases of the proposed Twenty-two International Sites, and then have selected at least five sources of them that were more relevant. The final recommendations have proposed by agreement of technical team and Guideline Review Committee. In less than 5 months, more than 500 authors in whole country have selected to prepare guidelines and, approximately 150 guidelines have provided in three volumes of the published and distributed book. Each guideline had a national ID number, constant forever; all topics should be reviewed every 3-5 years. National health guideline(s) would be essential means for policy making in health system and increased the cost containment and quality of care. Ministry of Health and Medical Education should provide and distribute the guidelines based on its accountability to legal responsibility.

  5. An approach to designing a national climate service

    PubMed Central

    Miles, E. L.; Snover, A. K.; Whitely Binder, L. C.; Sarachik, E. S.; Mote, P. W.; Mantua, N.

    2006-01-01

    Climate variability and change are considerably important for a wide range of human activities and natural ecosystems. Climate science has made major advances during the last two decades, yet climate information is neither routinely useful for nor used in planning. What is needed is a mechanism, a national climate service (NCS), to connect climate science to decision-relevant questions and support building capacity to anticipate, plan for, and adapt to climate fluctuations. This article contributes to the national debate for an NCS by describing the rationale for building an NCS, the functions and services it would provide, and how it should be designed and evaluated. The NCS is most effectively achieved as a federal interagency partnership with critically important participation by regional climate centers, state climatologists, the emerging National Integrated Drought Information System, and the National Oceanic and Atmospheric Administration (NOAA) Regional Integrated Sciences Assessment (RISA) teams in a sustained relationship with a wide variety of stakeholders. Because the NCS is a service, and because evidence indicates that the regional spatial scale is most important for delivering climate services, given subnational geographical/geophysical complexity, attention is focused on lessons learned from the University of Washington Climate Impacts Group's 10 years of experience, the first of the NOAA RISA teams. PMID:17158218

  6. An approach to designing a national climate service.

    PubMed

    Miles, E L; Snover, A K; Whitely Binder, L C; Sarachik, E S; Mote, P W; Mantua, N

    2006-12-26

    Climate variability and change are considerably important for a wide range of human activities and natural ecosystems. Climate science has made major advances during the last two decades, yet climate information is neither routinely useful for nor used in planning. What is needed is a mechanism, a national climate service (NCS), to connect climate science to decision-relevant questions and support building capacity to anticipate, plan for, and adapt to climate fluctuations. This article contributes to the national debate for an NCS by describing the rationale for building an NCS, the functions and services it would provide, and how it should be designed and evaluated. The NCS is most effectively achieved as a federal interagency partnership with critically important participation by regional climate centers, state climatologists, the emerging National Integrated Drought Information System, and the National Oceanic and Atmospheric Administration (NOAA) Regional Integrated Sciences Assessment (RISA) teams in a sustained relationship with a wide variety of stakeholders. Because the NCS is a service, and because evidence indicates that the regional spatial scale is most important for delivering climate services, given subnational geographical/geophysical complexity, attention is focused on lessons learned from the University of Washington Climate Impacts Group's 10 years of experience, the first of the NOAA RISA teams.

  7. Outbreak of Salmonella infantis infection in a large animal veterinary teaching hospital.

    PubMed

    Tillotson, K; Savage, C J; Salman, M D; Gentry-Weeks, C R; Rice, D; Fedorka-Cray, P J; Hendrickson, D A; Jones, R L; Nelson, W; Traub-Dargatz, J L

    1997-12-15

    During the past 11 years, there have been numerous reports of outbreaks of salmonellosis involving horses in veterinary teaching hospitals. Some of these outbreaks have been associated with Salmonella serotypes not commonly associated with infection of horses. Salmonella infantis is among the more common Salmonella serotypes isolated from human beings, and is an important pathogen in the broiler chicken industry. However, it was not commonly isolated from horses or cattle on a national basis between 1993 and 1995. In this report, we describe an outbreak of S infantis infection among large animals, primarily horses, in a veterinary teaching hospital and the control measures that were implemented. Factors that appeared to be key in control of this outbreak in this hospital included providing biosecurity training sessions for hospital personnel, adopting a standard operating procedure manual for biosecurity procedures, installing additional handwashing sinks throughout the facility, painting the interior of the facility with a nontoxic readily cleanable paint, replacing the dirt flooring in 4 stalls with concrete flooring, and removing noncleanable surfaces such as rubber stall mats, wooden hay storage bins, and open grain bins. Our experience with this outbreak suggests that although it is virtually impossible to eliminate Salmonella organisms from the environment, minimizing contamination is possible. Prevention of nosocomial infection must be approached in a multifaceted manner and care must be taken to search out covert sources of contamination, especially if standard intervention procedures do not prevent spread of the disease.

  8. A participatory approach to evaluating a national training and institutional change initiative: the BUILD longitudinal evaluation.

    PubMed

    Davidson, Pamela L; Maccalla, Nicole M G; Afifi, Abdelmonem A; Guerrero, Lourdes; Nakazono, Terry T; Zhong, Shujin; Wallace, Steven P

    2017-01-01

    The National Institutes of Health (NIH) funds training programs to increase the numbers and skills of scientists who obtain NIH research grants, but few programs have been rigorously evaluated. The sizeable recent NIH investment in developing programs to increase the diversity of the NIH-funded workforce, implemented through the Diversity Program Consortium (DPC), is unusual in that it also funds a Consortium-wide evaluation plan, which spans the activities of the 10 BUilding Infrastructure Leading to Diversity (BUILD) awardees and the National Research Mentoring Network (NRMN). The purpose of this article is to describe the evaluation design and innovations of the BUILD Program on students, faculty, and institutions of the 10 primarily undergraduate BUILD sites. Our approach to this multi-methods quasi-experimental longitudinal evaluation emphasizes stakeholder participation and collaboration. The evaluation plan specifies the major evaluation questions and key short- to long-term outcome measures (or Hallmarks of Success). The Coordination and Evaluation Center (CEC) embarked on a comprehensive evaluation strategy by developing a set of logic models that incorporate the Hallmarks of Success and other outcomes that were collaboratively identified by the DPC. Data were collected from each BUILD site through national surveys from the Higher Education Research Institute at UCLA (HERI), annual followup surveys that align with the HERI instruments, site visits and case studies, program encounter data ("tracker" data), and institutional data. The analytic approach involves comparing changes in Hallmarks (key outcomes) within institutions for biomedical students who participated versus those who did not participate in the BUILD program at each institution, as well as between institution patterns of biomedical students at the BUILD sites, and matched institutions that were not BUILD grantees. Case studies provide insights into the institutionalization of these new

  9. Current legal regime for environmental impact assessment in areas beyond national jurisdiction and its future approaches

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ma, Deqiang; Coastal and Ocean Management Institute, Xiamen University, 361102; Fang, Qinhua, E-mail: qhfang@xmu.edu.cn

    In 2004, the United Nations launched an Ad Hoc Open-ended Informal Working Group to study issues relating to the conservation and sustainable use of marine biological diversity in areas beyond national jurisdiction. Since then, the topic of governing marine areas beyond national jurisdiction (ABNJ) has been widely discussed by politicians, policy makers and scholars. As one of management tools to protect marine biodiversity in ABNJ, environmental impact assessment (EIA) has been widely recognized and accepted by the international community, however, the biggest challenge is how to effectively implement the EIA regime in ABNJ. This paper explores the impacts of anthropogenicmore » activities in ABNJ on marine ecosystems, reviews the existing legal regime for EIA in ABNJ and discusses possible measures to strengthen the implementation of EIA in ABNJ. - Highlights: • We identify human activities in ABNJ and their impacts on marine ecosystems. • We analyze the characters and gaps of the existing legal regime for EIA in ABNJ. • We analyze the pros and cons of alternative approaches of EIA in ABNJ.« less

  10. Real-time laboratory exercises to test contingency plans for classical swine fever: experiences from two national laboratories.

    PubMed

    Koenen, F; Uttenthal, A; Meindl-Böhmer, A

    2007-12-01

    In order to adequately and efficiently handle outbreaks of contagious diseases such as classical swine fever (CSF), foot and mouth disease or highly pathogenic avian influenza, competent authorities and the laboratories involved have to be well prepared and must be in possession of functioning contingency plans. These plans should ensure that in the event of an outbreak access to facilities, equipment, resources, trained personnel, and all other facilities needed for the rapid and efficient eradication of the outbreak is guaranteed, and that the procedures to follow are well rehearsed. It is essential that these plans are established during 'peace-time' and are reviewed regularly. This paper provides suggestions on how to perform laboratory exercises to test preparedness and describes the experiences of two national reference laboratories for CSF. The major lesson learnt was the importance of a well-documented laboratory contingency plan. The major pitfalls encountered were shortage of space, difficulties in guaranteeing biosecurity and sufficient supplies of sterile equipment and consumables. The need for a standardised laboratory information management system, that is used by all those involved in order to reduce the administrative load, is also discussed.

  11. Assessment of the Partially Resolved Numerical Simulation (PRNS) Approach in the National Combustion Code (NCC) for Turbulent Nonreacting and Reacting Flows

    NASA Technical Reports Server (NTRS)

    Shih, Tsan-Hsing; Liu, Nan-Suey

    2008-01-01

    This paper describes an approach which aims at bridging the gap between the traditional Reynolds-averaged Navier-Stokes (RANS) approach and the traditional large eddy simulation (LES) approach. It has the characteristics of the very large eddy simulation (VLES) and we call this approach the partially-resolved numerical simulation (PRNS). Systematic simulations using the National Combustion Code (NCC) have been carried out for fully developed turbulent pipe flows at different Reynolds numbers to evaluate the PRNS approach. Also presented are the sample results of two demonstration cases: nonreacting flow in a single injector flame tube and reacting flow in a Lean Direct Injection (LDI) hydrogen combustor.

  12. NATIONAL COASTAL ASSESSMENT APPROACH AND FINDINGS IN THE NORTHEAST

    EPA Science Inventory

    The National Coastal Assessment (NCA) has three major goals: 1) assess ecological condition of the nation's estuarine resources based on comparable data of known quality, 2) determine reference conditions for more detailed studies of ecological stressors and responses, and 3) he...

  13. A MULTIDISCIPLINARY APPROACH TO SUB-NATIONAL SUSTAINABILITY

    EPA Science Inventory

    The USEPA is investigating sustainability metrics from an economic and environmental perspective to determine their applicability at a sub-national level. Metrics are derived from Ecological Footprint, Emergy Analysis, Net Regional Product, and Fisher Information. We chose severa...

  14. SUB-NATIONAL SUSTAINABILITY FROM A MULTIDISCIPLINARY APPROACH

    EPA Science Inventory

    The USEPA is investigating sustainability metrics from an economic and environmental perspective to determine their applicability at a sub-national level. Metrics are derived from Ecological Footprint, Emergy Analysis, Net Regional Product, and Fisher Information. We chose severa...

  15. Japan's National Curriculum Reforms: Focus on Integrated Curriculum Approach

    ERIC Educational Resources Information Center

    Arani, Mohammad Reza Sarkar

    2008-01-01

    This article describes the process of national curriculum standards reform and the progress of applying the integrated curriculum from theory and research to practice. The curriculum council of Japanese government received an inquiry from Monbusho in August 1996 about "reform of the national curriculum". The council comprehensively…

  16. From partnerships to networks: new approaches for measuring U.S. National Heritage Area effectiveness.

    PubMed

    Laven, Daniel N; Krymkowski, Daniel H; Ventriss, Curtis L; Manning, Robert E; Mitchell, Nora J

    2010-08-01

    National Heritage Areas (NHAs) are an alternative and increasingly popular form of protected area management in the United States. NHAs seek to integrate environmental objectives with community and economic objectives at regional or landscape scales. NHA designations have increased rapidly in the last 20 years, generating a substantial need for evaluative information about (a) how NHAs work; (b) outcomes associated with the NHA process; and (c) the costs and benefits of investing public moneys into the NHA approach. Qualitative evaluation studies recently conducted at three NHAs have identified the importance of understanding network structure and function in the context of evaluating NHA management effectiveness. This article extends these case studies by examining quantitative network data from each of the sites. The authors analyze these data using both a descriptive approach and a statistically more robust approach known as exponential random graph modeling. Study findings indicate the presence of transitive structures and the absence of three-cycle structures in each of these networks. This suggests that these networks are relatively ''open,'' which may be desirable, given the uncertainty of the environments in which they operate. These findings also suggest, at least at the sites reported here, that the NHA approach may be an effective way to activate and develop networks of intersectoral organizational partners. Finally, this study demonstrates the utility of using quantitative network analysis to better understand the effectiveness of protected area management models that rely on partnership networks to achieve their intended outcomes.

  17. The dilemma of dual use biological research: Polish perspective.

    PubMed

    Czarkowski, Marek

    2010-03-01

    Biological research with legitimate scientific purpose that may be misused to pose a biological threat to public health and/or national security is termed dual use. In Poland there are adequate conditions for conducting experiments that could be qualified as dual use research, and therefore, a risk of attack on Poland or other countries exists. Optimal solutions for limiting such threats are required, and the national system of biosecurity should enable early, reliable, and complete identification of this type of research. Scientists should have a fundamental role in this process, their duty being to immediately, upon identification, report research with dual use potential. An important entity in the identification system of dual use research should also be the Central Register of Biological and Biomedical Research, which gathers information about all biological and biomedical research being conducted in a given country. Publishers, editors, and review committees of journals and other scientific publications should be involved in evaluating results of clinical trials. The National Council of Biosecurity should be the governmental institution responsible for developing a system of dual use research threat prevention. Its role would be to develop codes of conduct, form counsel of expertise, and monitor the problem at national level, while the Dual Use Research Committee would be responsible for individual cases. In Poland, current actions aiming to provide biological safety were based on developing and passing an act about genetically modified organisms (GMO's) and creating a GMO Committee. Considering experiences of other nations, one should view these actions as fragmentary, and thus insufficient protection against dual use research threats.

  18. Acoustic Sensor Planning for Gunshot Location in National Parks: A Pareto Front Approach

    PubMed Central

    González-Castaño, Francisco Javier; Alonso, Javier Vales; Costa-Montenegro, Enrique; López-Matencio, Pablo; Vicente-Carrasco, Francisco; Parrado-García, Francisco J.; Gil-Castiñeira, Felipe; Costas-Rodríguez, Sergio

    2009-01-01

    In this paper, we propose a solution for gunshot location in national parks. In Spain there are agencies such as SEPRONA that fight against poaching with considerable success. The DiANa project, which is endorsed by Cabaneros National Park and the SEPRONA service, proposes a system to automatically detect and locate gunshots. This work presents its technical aspects related to network design and planning. The system consists of a network of acoustic sensors that locate gunshots by hyperbolic multi-lateration estimation. The differences in sound time arrivals allow the computation of a low error estimator of gunshot location. The accuracy of this method depends on tight sensor clock synchronization, which an ad-hoc time synchronization protocol provides. On the other hand, since the areas under surveillance are wide, and electric power is scarce, it is necessary to maximize detection coverage and minimize system cost at the same time. Therefore, sensor network planning has two targets, i.e., coverage and cost. We model planning as an unconstrained problem with two objective functions. We determine a set of candidate solutions of interest by combining a derivative-free descent method we have recently proposed with a Pareto front approach. The results are clearly superior to random seeding in a realistic simulation scenario. PMID:22303135

  19. Acoustic sensor planning for gunshot location in national parks: a pareto front approach.

    PubMed

    González-Castaño, Francisco Javier; Alonso, Javier Vales; Costa-Montenegro, Enrique; López-Matencio, Pablo; Vicente-Carrasco, Francisco; Parrado-García, Francisco J; Gil-Castiñeira, Felipe; Costas-Rodríguez, Sergio

    2009-01-01

    In this paper, we propose a solution for gunshot location in national parks. In Spain there are agencies such as SEPRONA that fight against poaching with considerable success. The DiANa project, which is endorsed by Cabaneros National Park and the SEPRONA service, proposes a system to automatically detect and locate gunshots. This work presents its technical aspects related to network design and planning. The system consists of a network of acoustic sensors that locate gunshots by hyperbolic multi-lateration estimation. The differences in sound time arrivals allow the computation of a low error estimator of gunshot location. The accuracy of this method depends on tight sensor clock synchronization, which an ad-hoc time synchronization protocol provides. On the other hand, since the areas under surveillance are wide, and electric power is scarce, it is necessary to maximize detection coverage and minimize system cost at the same time. Therefore, sensor network planning has two targets, i.e., coverage and cost. We model planning as an unconstrained problem with two objective functions. We determine a set of candidate solutions of interest by combining a derivative-free descent method we have recently proposed with a Pareto front approach. The results are clearly superior to random seeding in a realistic simulation scenario.

  20. Insight into Alternative Approaches for Control of Avian Influenza in Poultry, with Emphasis on Highly Pathogenic H5N1

    PubMed Central

    Abdelwhab, E. M.; Hafez, Hafez M.

    2012-01-01

    Highly pathogenic avian influenza virus (HPAIV) of subtype H5N1 causes a devastating disease in poultry but when it accidentally infects humans it can cause death. Therefore, decrease the incidence of H5N1 in humans needs to focus on prevention and control of poultry infections. Conventional control strategies in poultry based on surveillance, stamping out, movement restriction and enforcement of biosecurity measures did not prevent the virus spreading, particularly in developing countries. Several challenges limit efficiency of the vaccines to prevent outbreaks of HPAIV H5N1 in endemic countries. Alternative and complementary approaches to reduce the current burden of H5N1 epidemics in poultry should be encouraged. The use of antiviral chemotherapy and natural compounds, avian-cytokines, RNA interference, genetic breeding and/or development of transgenic poultry warrant further evaluation as integrated intervention strategies for control of HPAIV H5N1 in poultry. PMID:23202521

  1. Multi-hazard national-level risk assessment in Africa using global approaches

    NASA Astrophysics Data System (ADS)

    Fraser, Stuart; Jongman, Brenden; Simpson, Alanna; Murnane, Richard

    2016-04-01

    In recent years Sub-Saharan Africa has been characterized by unprecedented opportunity for transformation and sustained growth. However, natural disasters such as droughts, floods, cyclones, earthquakes, landslides, volcanic eruptions and extreme temperatures cause significant economic and human losses, and major development challenges. Quantitative disaster risk assessments are an important basis for governments to understand disaster risk in their country, and to develop effective risk management and risk financing solutions. However, the data-scarce nature of many Sub-Saharan African countries as well as a lack of financing for risk assessments has long prevented detailed analytics. Recent advances in globally applicable disaster risk modelling practices and data availability offer new opportunities. In December 2013 the European Union approved a € 60 million contribution to support the development of an analytical basis for risk financing and to accelerate the effective implementation of a comprehensive disaster risk reduction. The World Bank's Global Facility for Disaster Reduction and Recovery (GFDRR) was selected as the implementing partner of the Program for Result Area 5: the "Africa Disaster Risk Assessment and Financing Program." As part of this effort, the GFDRR is overseeing the production of national-level multi-hazard risk profiles for a range of countries in Sub-Saharan Africa, using a combination of national and global datasets and state-of-the-art hazard and risk assessment methodologies. In this presentation, we will highlight the analytical approach behind these assessments, and show results for the first five countries for which the assessment has been completed (Kenya, Uganda, Senegal, Niger and Ethiopia). The presentation will also demonstrate the visualization of the risk assessments into understandable and visually attractive risk profile documents.

  2. The National Children's Study: Recruitment Outcomes Using the Provider-Based Recruitment Approach.

    PubMed

    Hale, Daniel E; Wyatt, Sharon B; Buka, Stephen; Cherry, Debra; Cislo, Kendall K; Dudley, Donald J; McElfish, Pearl Anna; Norman, Gwendolyn S; Reynolds, Simone A; Siega-Riz, Anna Maria; Wadlinger, Sandra; Walker, Cheryl K; Robbins, James M

    2016-06-01

    In 2009, the National Children's Study (NCS) Vanguard Study tested the feasibility of household-based recruitment and participant enrollment using a birth-rate probability sample. In 2010, the NCS Program Office launched 3 additional recruitment approaches. We tested whether provider-based recruitment could improve recruitment outcomes compared with household-based recruitment. The NCS aimed to recruit 18- to 49-year-old women who were pregnant or at risk for becoming pregnant who lived in designated geographic segments within primary sampling units, generally counties. Using provider-based recruitment, 10 study centers engaged providers to enroll eligible participants at their practice. Recruitment models used different levels of provider engagement (full, intermediate, information-only). The percentage of eligible women per county ranged from 1.5% to 57.3%. Across the centers, 3371 potential participants were approached for screening, 3459 (92%) were screened and 1479 were eligible (43%). Of those 1181 (80.0%) gave consent and 1008 (94%) were retained until delivery. Recruited participants were generally representative of the county population. Provider-based recruitment was successful in recruiting NCS participants. Challenges included time-intensity of engaging the clinical practices, differential willingness of providers to participate, and necessary reliance on providers for participant identification. The vast majority of practices cooperated to some degree. Recruitment from obstetric practices is an effective means of obtaining a representative sample. Copyright © 2016 by the American Academy of Pediatrics.

  3. Integrating social marketing into sustainable resource management at Padre Island National Seashore: an attitude-based segmentation approach.

    PubMed

    Lai, Po-Hsin; Sorice, Michael G; Nepal, Sanjay K; Cheng, Chia-Kuen

    2009-06-01

    High demand for outdoor recreation and increasing diversity in outdoor recreation participants have imposed a great challenge on the National Park Service (NPS), which is tasked with the mission to provide open access for quality outdoor recreation and maintain the ecological integrity of the park system. In addition to management practices of education and restrictions, building a sense of natural resource stewardship among visitors may also facilitate the NPS ability to react to this challenge. The purpose of our study is to suggest a segmentation approach that is built on the social marketing framework and aimed at influencing visitor behaviors to support conservation. Attitude toward natural resource management, an indicator of natural resource stewardship, is used as the basis for segmenting park visitors. This segmentation approach is examined based on a survey of 987 visitors to the Padre Island National Seashore (PAIS) in Texas in 2003. Results of the K-means cluster analysis identify three visitor segments: Conservation-Oriented, Development-Oriented, and Status Quo visitors. This segmentation solution is verified using respondents' socio-demographic backgrounds, use patterns, experience preferences, and attitudes toward a proposed regulation. Suggestions are provided to better target the three visitor segments and facilitate a sense of natural resource stewardship among them.

  4. Medical Countermeasure Product Development - Alternatives Paper

    DTIC Science & Technology

    2014-04-01

    Maritime Research Laboratory of the Defence Science and Technology Organisation (DSTO) in 1995 as a Research Scientist. In January 1997 he was promoted... biosecurity role to supply to the Government and the World Health Organisation (WHO). In the future there may be circumstances where there is no... standards to solve national priority CBR or infectious disease threats. The PPP may enable Government to: • access and grow product development

  5. [Dimensional analysis of the concept of biosafety due to bioterrorism].

    PubMed

    Bernard, Laurence; Shaha, Maya

    2014-03-01

    In recent years with the strengthening of the discourse surrounding the biological risk of bioterrorist nature, the concept of biosafety emerged gradually. A dimensional analysis was used to contextualize the concept. Initially, biosafety was essentially a technical term related to the risks of contamination in laboratories or food industry and then be used to protect biodiversity against the spread of genetically modified organisms (GMOs) into the environment. Now, it is increasingly used in reference to the prevention and infections control, even though its use remains marginal. However, biosecurity may be defined as the security of life and therefore affect the safety devices participating in the government of bodies and power over life. A more critical approach including social and political dimensions within a Foucauldian perspective is needed to expand the scope of the biosecurity concept up to biological hazards constructs.

  6. Ageing and the economic life cycle: The National Transfer Accounts approach.

    PubMed

    Temple, Jeromey B; Rice, James M; McDonald, Peter F

    2017-12-01

    To illustrate the use of National Transfer Accounts (NTA) for understanding ageing and the economic life cycle in Australia. The NTA methodology is applied utilising a range of unit record, demographic and administrative data sets from 1981 to 2010. During early and later life, total consumption (public and private) is greater than labour income. On a time series and cohort basis, we show that each successive generation has improved their level of well-being (as measured by consumption) relative to the previous years or previous cohorts from 1981 to 1982 onwards. We also show a substantial increase in labour income earned by mature age workers over this period. International comparisons show Australia to have consumption and labour income age profiles very similar to those of Canada but dissimilar to many other countries, driven by differences in demographic and policy settings. The NTA approach provides a powerful framework to track differences in the economic life cycle across age groups, across time, across cohorts and across countries. © 2017 AJA Inc.

  7. How to use The National Gallery as a cross curricular approach to weather and climate studies at primary level.

    NASA Astrophysics Data System (ADS)

    Hansen, P. J. K.

    2009-09-01

    How to use The National Gallery as a cross curricular approach to weather and climate studies at primary level. Pål J. Kirkeby Hansen Faculty of Education and International Studies, Oslo University College (PalKirkeby.Hansen@lui.hio.no) Weather and climate are topics in natural science and geography in primary and secondary education in most countries. The pupils are often doing own weather observations and measurements and are presenting the results oral, by posters or with digital aids. They also use the Internet with all its relevant resources in their studies to develop vocabulary, practical and conceptual knowledge. Knowledge about weather and climate is parts of liberal education and could be projected to other topics in science and to topics in other subjects, for instance: history, social geography, literature and arts. This article reports from a case study in grade 3 classes (age 9 year) during their Weather Week. Their science teacher was, quite untypical, also educated in art history. She arranged a visited to The National Gallery with the double agenda: 1. To introduce the pupils to Norwegian canon paintings from the national romantic period, our so-called "golden age”. 2. To look for and discuss weather elements in this paintings. For one hour the museum curator guided the pupils around the water cycle by using the paintings. While the pupils' own observations of weather, clouds and wind and measurements of temperature and precipitation during the Weather Week only are point checks, the guided tour in The National Gallery gave literally "the whole picture” of the Norwegian weather and climate and of the water cycle. During the tour, the curator constantly invited the pupils to tell about and discuss what weather and water elements they were looking at when standing in front of a painting. The pupils were responsive and interested all the time. Back at school, they demonstrated that they had learned much about both weather elements, the water

  8. National Nutritional Programs for the 2012 London Olympic Games: a systematic approach by three different countries.

    PubMed

    Burke, Louise M; Meyer, Nanna L; Pearce, Jeni

    2013-01-01

    Preparing a national team for success at major sporting competitions such as the Olympic Games has become a systematic and multi-faceted activity. Sports nutrition contributes to this success via strategic nutritional interventions that optimize the outcomes from both the training process and the competitive event. This review summarizes the National Nutrition Programs involved with the 2012 London Olympic Games preparation of the Australian, British and American sports systems from the viewpoints of three key agencies: the Australian Institute of Sport, the English Institute of Sport and the United States Olympic Committee. Aspects include development of a nutrition network involving appropriately qualified sports dietitians/nutritionists within a multi-disciplinary team, recognition of continual updates in sports nutrition knowledge, and a systematic approach to service delivery, education and research within the athlete's daily training environment. Issues of clinical nutrition support must often be integrated into the performance nutrition matrix. Food service plays an important role in the achievement of nutrition goals during the Olympic Games, both through the efforts of the Athlete Dining Hall and catering activities of the host Olympic Games Organizing Committees as well as adjunct facilities often provided by National Olympic Committees for their own athletes. Copyright © 2013 Nestec Ltd., Vevey/S. Karger AG, Basel.

  9. Determining the Role of Language and Culture in First Nations Schools: A Comparison of the First Nations Education Act with the Policy of the Assembly of First Nations

    ERIC Educational Resources Information Center

    Morcom, Lindsay A.

    2014-01-01

    In this article, I explore the incongruence between the federal government's proposed First Nations Education Act and the approach of the Assembly of First Nations (AFN) regarding language and culture education. I also examine research concerning potential outcomes of their approaches to determine what would be most beneficial to learners.…

  10. A local space time kriging approach applied to a national outpatient malaria data set

    NASA Astrophysics Data System (ADS)

    Gething, P. W.; Atkinson, P. M.; Noor, A. M.; Gikandi, P. W.; Hay, S. I.; Nixon, M. S.

    2007-10-01

    Increases in the availability of reliable health data are widely recognised as essential for efforts to strengthen health-care systems in resource-poor settings worldwide. Effective health-system planning requires comprehensive and up-to-date information on a range of health metrics and this requirement is generally addressed by a Health Management Information System (HMIS) that coordinates the routine collection of data at individual health facilities and their compilation into national databases. In many resource-poor settings, these systems are inadequate and national databases often contain only a small proportion of the expected records. In this paper, we take an important health metric in Kenya (the proportion of outpatient treatments for malaria (MP)) from the national HMIS database and predict the values of MP at facilities where monthly records are missing. The available MP data were densely distributed across a spatiotemporal domain and displayed second-order heterogeneity. We used three different kriging methodologies to make cross-validation predictions of MP in order to test the effect on prediction accuracy of (a) the extension of a spatial-only to a space-time prediction approach, and (b) the replacement of a globally stationary with a locally varying random function model. Space-time kriging was found to produce predictions with 98.4% less mean bias and 14.8% smaller mean imprecision than conventional spatial-only kriging. A modification of space-time kriging that allowed space-time variograms to be recalculated for every prediction location within a spatially local neighbourhood resulted in a larger decrease in mean imprecision over ordinary kriging (18.3%) although the mean bias was reduced less (87.5%).

  11. A local space–time kriging approach applied to a national outpatient malaria data set

    PubMed Central

    Gething, P.W.; Atkinson, P.M.; Noor, A.M.; Gikandi, P.W.; Hay, S.I.; Nixon, M.S.

    2007-01-01

    Increases in the availability of reliable health data are widely recognised as essential for efforts to strengthen health-care systems in resource-poor settings worldwide. Effective health-system planning requires comprehensive and up-to-date information on a range of health metrics and this requirement is generally addressed by a Health Management Information System (HMIS) that coordinates the routine collection of data at individual health facilities and their compilation into national databases. In many resource-poor settings, these systems are inadequate and national databases often contain only a small proportion of the expected records. In this paper, we take an important health metric in Kenya (the proportion of outpatient treatments for malaria (MP)) from the national HMIS database and predict the values of MP at facilities where monthly records are missing. The available MP data were densely distributed across a spatiotemporal domain and displayed second-order heterogeneity. We used three different kriging methodologies to make cross-validation predictions of MP in order to test the effect on prediction accuracy of (a) the extension of a spatial-only to a space–time prediction approach, and (b) the replacement of a globally stationary with a locally varying random function model. Space–time kriging was found to produce predictions with 98.4% less mean bias and 14.8% smaller mean imprecision than conventional spatial-only kriging. A modification of space–time kriging that allowed space–time variograms to be recalculated for every prediction location within a spatially local neighbourhood resulted in a larger decrease in mean imprecision over ordinary kriging (18.3%) although the mean bias was reduced less (87.5%). PMID:19424510

  12. Cross-National Prevalence of Traditional Bullying, Traditional Victimization, Cyberbullying and Cyber-Victimization: Comparing Single-Item and Multiple-Item Approaches of Measurement

    ERIC Educational Resources Information Center

    Yanagida, Takuya; Gradinger, Petra; Strohmeier, Dagmar; Solomontos-Kountouri, Olga; Trip, Simona; Bora, Carmen

    2016-01-01

    Many large-scale cross-national studies rely on a single-item measurement when comparing prevalence rates of traditional bullying, traditional victimization, cyberbullying, and cyber-victimization between countries. However, the reliability and validity of single-item measurement approaches are highly problematic and might be biased. Data from…

  13. Understanding Acceptable Level of Risk: Incorporating the Economic Cost of Under-Managing Invasive Species.

    PubMed

    Davidson, Alisha D; Hewitt, Chad L; Kashian, Donna R

    2015-01-01

    Management of nonindigenous species includes prevention, early detection and rapid response and control. Early detection and rapid response depend on prioritizing and monitoring sites at risk for arrival or secondary spread of nonindigenous species. Such monitoring efforts require sufficient biosecurity budgets to be effective and meet management or policy directives for reduced risk of introduction. Such consideration of risk reduction is rarely considered, however. Here, we review the concepts of acceptable level of risk (ALOR) and associated costs with respect to nonindigenous species and present a framework for aligning risk reduction priorities with available biosecurity resources. We conclude that available biosecurity resources may be insufficient to attain stated and desired risk reduction. This outcome highlights the need to consider policy and management directives when beginning a biosecurity program to determine the feasibility of risk reduction goals, given available resources.

  14. Epidemics and the politics of knowledge: contested narratives in Egypt's H1N1 response.

    PubMed

    Leach, Melissa; Tadros, Mariz

    2014-01-01

    This article explores the politics of knowledge involved in understanding and responding to epidemics in an era of global health governance and biosecurity. It develops and applies an approach focused on how multiple, competing narratives about epidemics are constructed, mobilized and interact, and selectively justify pathways of intervention and response. A detailed ethnographic case study of national and local responses to H1N1 influenza, so-called swine flu, in Egypt reveals how global narratives were reworked by powerful actors in a particular political context, suppressing and delegitimizing the alternative narratives of the Zabaleen (Coptic Christian) people whose lives and livelihoods centered on raising pigs and working with them to control urban waste. The case study illustrates important ways in which geographies and politics of blame around epidemics emerge and are justified, their political contexts and consequences, and how they may feed back to shape the dynamics of disease itself.

  15. Progress in national-scale landslide susceptibility mapping in Romania using a combined statistical-heuristical approach

    NASA Astrophysics Data System (ADS)

    Bălteanu, Dan; Micu, Mihai; Malet, Jean-Philippe; Jurchescu, Marta; Sima, Mihaela; Kucsicsa, Gheorghe; Dumitrică, Cristina; Petrea, Dănuţ; Mărgărint, Ciprian; Bilaşco, Ştefan; Văcăreanu, Radu; Georgescu, Sever; Senzaconi, Francisc

    2017-04-01

    Landslide processes represent a very widespread geohazard in Romania, affecting mainly the hilly and plateau regions as well as the mountain sectors developed on flysch formations. Two main projects provided the framework for improving the existing national landslide susceptibility map (Bălteanu et al. 2010): the ELSUS (Pan-European and nation-wide landslide susceptibility assessment, EC-CERG) and the RO-RISK (Disaster Risk Evaluation at National Level, ESF-POCA) projects. The latter one, a flagship project aiming at strengthening risk prevention and management in Romania, focused on a national-level evaluation of the main risks in the country including landslides. The strategy for modeling landslide susceptibility was designed based on the experience gained from continental and national level assessments conducted in the frame of the International Programme on Landslides (IPL) project IPL-162, the European Landslides Expert Group - JRC and the ELSUS project. The newly proposed landslide susceptibility model used as input a reduced set of landslide conditioning factor maps available at scales of 1:100,000 - 1:200,000 and consisting of lithology, slope angle and land cover. The input data was further differentiated for specific natural environments, defined here as morpho-structural units in order to incorporate differences induced by elevation (vertical climatic zonation), morpho-structure as well as neotectonic features. In order to best discern the specific landslide conditioning elements, the analysis has been carried out for one single process category, namely slides. The existence of a landslide inventory covering the whole country's territory ( 30,000 records, Micu et al. 2014), although affected by incompleteness and lack of homogeneity, allowed for the application of a semi-quantitative, mixed statistical-heuristical approach having the advantage of combining the objectivity of statistics with expert-knowledge in calibrating class and factor weights. The

  16. The National Children’s Study: Recruitment Outcomes Using the Provider-Based Recruitment Approach

    PubMed Central

    Wyatt, Sharon B.; Buka, Stephen; Cherry, Debra; Cislo, Kendall K.; Dudley, Donald J.; McElfish, Pearl Anna; Norman, Gwendolyn S.; Reynolds, Simone A.; Siega-Riz, Anna Maria; Wadlinger, Sandra; Walker, Cheryl K.; Robbins, James M.

    2016-01-01

    OBJECTIVE: In 2009, the National Children’s Study (NCS) Vanguard Study tested the feasibility of household-based recruitment and participant enrollment using a birth-rate probability sample. In 2010, the NCS Program Office launched 3 additional recruitment approaches. We tested whether provider-based recruitment could improve recruitment outcomes compared with household-based recruitment. METHODS: The NCS aimed to recruit 18- to 49-year-old women who were pregnant or at risk for becoming pregnant who lived in designated geographic segments within primary sampling units, generally counties. Using provider-based recruitment, 10 study centers engaged providers to enroll eligible participants at their practice. Recruitment models used different levels of provider engagement (full, intermediate, information-only). RESULTS: The percentage of eligible women per county ranged from 1.5% to 57.3%. Across the centers, 3371 potential participants were approached for screening, 3459 (92%) were screened and 1479 were eligible (43%). Of those 1181 (80.0%) gave consent and 1008 (94%) were retained until delivery. Recruited participants were generally representative of the county population. CONCLUSIONS: Provider-based recruitment was successful in recruiting NCS participants. Challenges included time-intensity of engaging the clinical practices, differential willingness of providers to participate, and necessary reliance on providers for participant identification. The vast majority of practices cooperated to some degree. Recruitment from obstetric practices is an effective means of obtaining a representative sample. PMID:27251870

  17. Public health situation awareness: toward a semantic approach

    NASA Astrophysics Data System (ADS)

    Mirhaji, Parsa; Richesson, Rachel L.; Turley, James P.; Zhang, Jiajie; Smith, Jack W.

    2004-04-01

    We propose a knowledge-based public health situation awareness system. The basis for this system is an explicit representation of public health situation awareness concepts and their interrelationships. This representation is based upon the users" (public health decision makers) cognitive model of the world, and optimized towards the efficacy of performance and relevance to the public health situation awareness processes and tasks. In our approach, explicit domain knowledge is the foundation for interpretation of public health data, as apposed to conventional systems where the statistical methods are the essence of the processes. Objectives: To develop a prototype knowledge-based system for public health situation awareness and to demonstrate the utility of knowledge intensive approaches in integration of heterogeneous information, eliminating the effects of incomplete and poor quality surveillance data, uncertainty in syndrome and aberration detection and visualization of complex information structures in public health surveillance settings, particularly in the context of bioterrorism (BT) preparedness. The system employs the Resource Definition Framework (RDF) and additional layers of more expressive languages to explicate the knowledge of domain experts into machine interpretable and computable problem-solving modules that can then guide users and computer systems in sifting through the most "relevant" data for syndrome and outbreak detection and investigation of root cause of the event. The Center for Biosecurity and Public Health Informatics Research is developing a prototype knowledge-based system around influenza, which has complex natural disease patterns, many public health implications, and is a potential agent for bioterrorism. The preliminary data from this effort may demonstrate superior performance in information integration, syndrome and aberration detection, information access through information visualization, and cross-domain investigation of the

  18. Developing a new national approach to surveillance for ventilator-associated events: executive summary.

    PubMed

    Magill, Shelley S; Klompas, Michael; Balk, Robert; Burns, Suzanne M; Deutschman, Clifford S; Diekema, Daniel; Fridkin, Scott; Greene, Linda; Guh, Alice; Gutterman, David; Hammer, Beth; Henderson, David; Hess, Dean R; Hill, Nicholas S; Horan, Teresa; Kollef, Marin; Levy, Mitchell; Septimus, Edward; VanAntwerpen, Carole; Wright, Don; Lipsett, Pamela

    2013-11-01

    In September 2011, the Centers for Disease Control and Prevention (CDC) convened a Ventilator-Associated Pneumonia (VAP) Surveillance Definition Working Group to organize a formal process for leaders and experts of key stakeholder organizations to discuss the challenges of VAP surveillance definitions and to propose new approaches to VAP surveillance in adult patients (Table 1). The charges to the Working Group were to (1) critically review a draft, streamlined VAP surveillance definition developed for use in adult patients; (2) suggest modifications to enhance the reliability and credibility of the surveillance definition within the critical care and infection prevention communities; and (3) propose a final adult surveillance definition algorithm to be implemented in the CDC's National Healthcare Safety Network (NHSN), taking into consideration the potential future use of the definition algorithm in public reporting, interfacility comparisons, and pay-for-reporting and pay-for-performance programs. Published by Mosby, Inc.

  19. Education and Criminal Justice: The Educational Approach to Prison Administration. The United Nations Standard Minimum Rules for the Treatment of Prisoners.

    ERIC Educational Resources Information Center

    Morin, Lucien; Cosman, J. W.

    The United Nations Standard Minimum Rules for the Treatment of Prisoners do not express the basic principle that would support a serious educational approach to prison administration. The crucial missing rationale is the concept of the inherent dignity of the individual human prisoner. This concept has certain basic educational implications,…

  20. 76 FR 4139 - National Ocean Council; Development of Strategic Action Plans for the National Policy for the...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-24

    ... OFFICE OF SCIENCE AND TECHNOLOGY POLICY National Ocean Council; Development of Strategic Action Plans for the National Policy for the Stewardship of the Ocean, Our Coasts, and the Great Lakes ACTION... the Great Lakes. The National Policy provides a comprehensive approach, based on science and...

  1. The Effect of the Post 2001 Reforms on FMD Risks of the International Live Animal Trade.

    PubMed

    Shanafelt, David W; Perrings, C

    2018-02-27

    The 2001 UK foot and mouth disease (FMD) epidemic marked a change in global FMD management, focusing less on trade isolation than on biosecurity within countries where FMD is endemic. Post 2001 policy calls for the isolation of disease-free zones in FMD-endemic countries, while increasing the opportunities for trade. The impact of the change on disease risk has yet to be tested. In this paper, we estimate an empirical model of disease risk that tests for the impact of trade volumes before and after 2001, controlling for biosecurity measures. In the pre 2001 regime, we find that poor biosecurity was associated with the probability of reporting an outbreak. In the post 2001 regime, the risks changed, with trade being a much greater source of risk. We discuss the trade-off between trade restrictions and biosecurity measures in the management of FMD disease risks.

  2. National Assessment Technical Quality.

    ERIC Educational Resources Information Center

    Chelimsky, Eleanor

    In 1991 the National Assessment Governing Board (NAGB) released a report interpreting the achievement of U.S. students in mathematics on the 1990 National Assessment of Educational Progress in terms of a set of performance standards. The NAGB had been designing and implementing an approach to defining basic, proficient, and advanced levels of…

  3. Ferretting out the facts behind the H5N1 controversy.

    PubMed

    Sleator, Roy D

    2012-01-01

    Recent recommendations by the National Science Advisory Board for Biosecurity (NSABB) to redact key methodological details of two studies involving mammal-to-mammal transmission of the H5N1 (H5) subtype influenza viruses, has led to a temporary moratorium on all research involving live H5N1 or H5 HA reassortant viruses shown to be transmissible in ferrets. Herein, I review the events which led to this impasse and comment on their impact.

  4. Great expectations--ethics, avian flu and the value of progress.

    PubMed

    Evans, Nicholas G

    2013-04-01

    A recent controversy over the US National Science Advisory Board for Biosecurity's recommendation to censor two publications on genetically modified H5N1 avian influenza has generated concern over the threat to scientific freedom such censorship presents. In this paper, I argue that in the case of these studies, appeals to scientific freedom are not sufficient to motivate a rejection of censorship. I then use this conclusion to draw broader concerns about the ethics of dual-use research.

  5. Engineering approaches to energy balance and obesity: opportunities for novel collaborations and research: report of a joint national science foundation and national institutes of health workshop.

    PubMed

    Ershow, Abby G; Ortega, Alfonso; Timothy Baldwin, J; Hill, James O

    2007-01-01

    Energy balance disorders account for a large public health burden. The obesity epidemic in particular is one of the most rapidly evolving public health problems of our day. At present, two-thirds of American adults and one-sixth of American children and adolescents are considered either overweight or obese. Public health concern about obesity is high because of the increased risk and increased mortality of cardiovascular disease, Type 2 diabetes, many forms of cancer, gallbladder disease, and osteoarthritis. These risks increase with the severity of the obesity. Excess adipose tissue, representing fat storage, ultimately derives from an imbalance between energy intake and energy expenditure. Conversely, undesirable and inadvertent loss of body weight and muscle mass, as seen in aging and cachectic states of chronic diseases such as heart failure and cancer, have serious clinical and functional consequences without satisfactory clinical or behavioral solutions. Innovative engineering technologies could help to address unresolved problems in energy balance, intake, and expenditure. Novel sensors, devices, imaging technologies, nanotechnologies, biomaterials, technologies to detect biochemical markers of energy balance, mathematical modeling, systems biology, and other approaches could be developed, evaluated, and leveraged through multidisciplinary collaborations. Engineers, physical scientists, and mathematicians can work with scientists from other relevant disciplines who possess expertise in obesity and nutrition. Furthermore, the possibility of re-engineering the "built environment" to encourage higher levels of physical activity has been suggested as another promising and important approach to which engineers can contribute (see http://www.obesityresearch.nih.gov). Ultimately, systematic application of the "Engineering Approach" can help in developing the needed technologies and tools to facilitate research and eventually support therapeutic advances and

  6. Use of Complementary Health Approaches Among Children Aged 4–17 Years in the United States: National Health Interview Survey, 2007–2012

    PubMed Central

    Black, Lindsey I.; Clarke, Tainya C.; Barnes, Patricia M.; Stussman, Barbara J.; Nahin, Richard L.

    2015-01-01

    Objective This report presents national estimates of the use of complementary health approaches among children aged 4–17 years in the United States. Selected modalities are compared for 2007 and 2012 to examine changes over time. Methods Data from the 2007 and 2012 National Health Interview Survey (NHIS) were analyzed for this report. The combined sample included 17,321 interviews with knowledgeable adults about children aged 4–17 years. Point estimates and estimates of their variances were calculated using SUDAAN software to account for the complex sampling design of NHIS. Differences between percentages were evaluated using two-sided significance tests at the 0.05 level. Results The use of complementary health approaches among children did not change significantly since 2007 (from 12.0% in 2007 to 11.6% in 2012). However, one approach, the use of traditional healers, showed a statistically significant decrease in use, from 1.1% in 2007 to 0.1% in 2012. No other significant decreases were identified. An increase in the use of yoga was observed during this period (from 2.3% in 2007 to 3.1% in 2012). Nonvitamin, nonmineral dietary supplements; chiropractic or osteopathic manipulation; and yoga, tai chi, or qi gong were the most commonly used complementary health approaches in both 2007 and 2012. Also consistent between 2007 and 2012 was that complementary health approaches were most frequently used for back or neck pain, head or chest cold, anxiety or stress, and other musculoskeletal conditions. PMID:25671583

  7. Multiple approaches to understanding and preventing elder abuse: Introduction to the cross-disciplinary National Institutes of Health workshop.

    PubMed

    Saylor, Katherine Witte

    2016-01-01

    On October 30, 2015, the National Institutes of Health (NIH) convened a workshop, "Multiple Approaches to Understanding and Preventing Elder Abuse," in Bethesda, Maryland. The workshop brought together experts from across disciplines to discuss research challenges, opportunities, and lessons learned from other fields. Participants included experts in elder abuse, child abuse, intimate partner violence (IPV), emergency medicine, and neuroscience. In this special issue of the Journal of Elder Abuse and Neglect, participants address topics explored before, during, and after the day-long workshop.

  8. Potential sources of Campylobacter infection on chicken farms: contamination and control of broiler-harvesting equipment, vehicles and personnel.

    PubMed

    Ridley, A; Morris, V; Gittins, J; Cawthraw, S; Harris, J; Edge, S; Allen, V

    2011-07-01

    To test the efficacy of enhanced biosecurity measures on poultry farms for reducing environmental contamination with Campylobacter during partial depopulation of broiler flocks prior to normal slaughter age. The study has also evaluated the risk of infection from live-bird transport crates that are routinely cleaned at the slaughterhouse, but may remain contaminated. On-farm sampling and Campylobacter isolation was undertaken to compare the prevalence of contamination on vehicles, equipment and catching personnel during farm visits that took place under normal or enhanced biosecurity. Campylobacters were found in almost all types of sample examined and enhanced biosecurity reduced the prevalence. However, the additional measures failed to prevent colonisation of the flocks. For transport crates, challenge trials involved exposure of broilers to commercially cleaned crates and genotyping of any campylobacters isolated. The birds were rapidly colonised with the same genotypes as those isolated from the cleaned crates. The enhanced biosecurity measures were insufficient to prevent flock colonisation, and the problem was exacerbated by inadequate cleaning of transport crates at the slaughterhouse. Current commercial practices in the United Kingdom facilitate the spread of campylobacters among broiler chicken flocks. Prevention of flock infection appears to require more stringent biosecurity than that studied here. © 2011 Crown Copyright. Journal of Applied Microbiology © 2011 The Society for Applied Microbiology.

  9. A national approach to diabetes foot risk stratification and foot care.

    PubMed

    Leese, G P; Stang, D; Pearson, D W

    2011-08-01

    The Scottish Diabetes Foot Action Group (SDG) has developed and introduced a national strategy plan for diabetic foot care across Scotland. This has involved the implementation of an evidence-based national foot screening and risk stratification programme that has already covered 61% of the population in just the first two years. Nationally agreed patient information foot leaflets and professional education material have been introduced, and a consensus for antibiotic use in the diabetic foot has been published. Information on multidisciplinary specialist foot services has been collected, indicating that 58% of Health Board areas have consultants with dedicated sessions in their job plan to a foot clinic, and 42% had integrated orthotic involvement. The SDG aims to increase these figures. Work has been undertaken to support local podiatry networks and improve communication between the specialist centre and the community. At a national level the SDG is working with Foot in Diabetes UK (FDUK) to recognize key podiatry skills by developing core competencies and a competency framework for the diabetes podiatrist and diabetes orthotist. The annual Scottish Diabetes Survey indicates some improvement in amputation rates with prevalence decreasing from 0.8% to 0.5%, and improved recording of foot ulceration at a national level. This national strategy has helped highlight the importance and difficulties facing diabetes foot care and should help to continue to improve the quality of care of people with diabetes who have foot-related problems.

  10. A Community-Based Approach to Leading the Nation in Smart Energy Use

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None, None

    2013-12-31

    Project Objectives The AEP Ohio gridSMART® Demonstration Project (Project) achieved the following objectives: • Built a secure, interoperable, and integrated smart grid infrastructure in northeast central Ohio that demonstrated the ability to maximize distribution system efficiency and reliability and consumer use of demand response programs that reduced energy consumption, peak demand, and fossil fuel emissions. • Actively attracted, educated, enlisted, and retained consumers in innovative business models that provided tools and information reducing consumption and peak demand. • Provided the U.S. Department of Energy (DOE) information to evaluate technologies and preferred smart grid business models to be extended nationally. Projectmore » Description Ohio Power Company (the surviving company of a merger with Columbus Southern Power Company), doing business as AEP Ohio (AEP Ohio), took a community-based approach and incorporated a full suite of advanced smart grid technologies for 110,000 consumers in an area selected for its concentration and diversity of distribution infrastructure and consumers. It was organized and aligned around: • Technology, implementation, and operations • Consumer and stakeholder acceptance • Data management and benefit assessment Combined, these functional areas served as the foundation of the Project to integrate commercially available products, innovative technologies, and new consumer products and services within a secure two-way communication network between the utility and consumers. The Project included Advanced Metering Infrastructure (AMI), Distribution Management System (DMS), Distribution Automation Circuit Reconfiguration (DACR), Volt VAR Optimization (VVO), and Consumer Programs (CP). These technologies were combined with two-way consumer communication and information sharing, demand response, dynamic pricing, and consumer products, such as plug-in electric vehicles and smart appliances. In addition, the

  11. Shock ignition: a new approach to high gain inertial confinement fusion on the national ignition facility.

    PubMed

    Perkins, L J; Betti, R; LaFortune, K N; Williams, W H

    2009-07-24

    Shock ignition, an alternative concept for igniting thermonuclear fuel, is explored as a new approach to high gain, inertial confinement fusion targets for the National Ignition Facility (NIF). Results indicate thermonuclear yields of approximately 120-250 MJ may be possible with laser drive energies of 1-1.6 MJ, while gains of approximately 50 may still be achievable at only approximately 0.2 MJ drive energy. The scaling of NIF energy gain with laser energy is found to be G approximately 126E (MJ);{0.510}. This offers the potential for high-gain targets that may lead to smaller, more economic fusion power reactors and a cheaper fusion energy development path.

  12. The WHO-ITU national eHealth strategy toolkit as an effective approach to national strategy development and implementation.

    PubMed

    Hamilton, Clayton

    2013-01-01

    With few exceptions, national eHealth strategies are the pivotal tools upon which the launch or refocusing of national eHealth programmes is hinged. The process of their development obviates cross-sector ministerial commitment led by the Ministry of Health. Yet countries often grapple with the task of strategy development and best efforts frequently fail to address strategic components of eHealth key to ensure successful implementation and stakeholder engagement. This can result in strategies that are narrowly focused, with an overemphasis placed on achieving technical outcomes. Without a clear link to a broader vision of health system development and a firm commitment from partners, the ability of a strategy to shape development of a national eHealth framework will be undermined and crucial momentum for implementation will be lost. WHO and ITU have sought to address this issue through the development of the National eHealth Strategy Toolkit that provides a basis for the components and processes to be considered in a strategy development or refocusing exercise. We look at this toolkit and highlight those areas which the countries should consider in formulating their national eHealth strategy.

  13. 76 FR 2328 - Submission for OMB Review; Comment Request

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-13

    ... analyzed and organized into descriptive reports. APHIS will use the data collected to: (1) Provide the...; (2) Evaluate the biosecurity risks associated with heifer-raising operations (e.g., commingling... development of a biosecurity assessment that can be used to evaluate the risk of disease transmission (e.g...

  14. Swedish Students' Experiences of National Testing in Science: A Narrative Approach

    ERIC Educational Resources Information Center

    Löfgren, Ragnhild; Löfgren, Håkan

    2017-01-01

    In Sweden, the policy of national testing was expanded in 2013 by introducing national tests in science in the sixth grade. The aim of this study is to contribute knowledge about the enactment of this policy of national testing by investigating students' experiences of taking the tests. Students were interviewed about their experiences of taking…

  15. National Lake Assessment 2012 Potenital Survey Design

    EPA Science Inventory

    In 2012 the Office of Water in collaboration with states and tribal nations will conduct the second National Lake Assessment. The purpose of this presentation is to present potential survey design approaches for this national assessment. Currently discussions are underway to de...

  16. Stuttering-Psycholinguistic Approach

    ERIC Educational Resources Information Center

    Hategan, Carolina Bodea; Anca, Maria; Prihoi, Lacramioara

    2012-01-01

    This research promotes psycholinguistic paradigm, it focusing in delimitating several specific particularities in stuttering pathology. Structural approach, on language sides proves both the recurrent aspects found within specialized national and international literature and the psycholinguistic approaches dependence on the features of the…

  17. Early Learnings from the National Library of New Zealand's National Digital Heritage Archive Project

    ERIC Educational Resources Information Center

    Knight, Steve

    2010-01-01

    Purpose: The purpose of this paper is to provide a brief description of the digital preservation programme at the National Library of New Zealand. Design/methodology/approach: Following a description of the legislative and strategic context for digital preservation in New Zealand, details are provided of the system for the National Digital…

  18. Compatibility; Incompatibility? Froebelian Principles and the Art National Curriculum.

    ERIC Educational Resources Information Center

    Payne, Margaret

    1993-01-01

    Asserts that the pedagogical approach proposed by Friedrich Froebel in the 1930s can be found in the Art National Curriculum in England. Describes the Art National Curriculum and links it to Froebel's integrated and sequenced approach to curriculum development and instruction. (CFR)

  19. 76 FR 22911 - National Advisory Council

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-04-25

    ... discussions on professionalism of emergency management, approaches for National Incident Management System... DEPARTMENT OF HOMELAND SECURITY Federal Emergency Management Agency [Docket ID FEMA-2007-0008] National Advisory Council AGENCY: Federal Emergency Management Agency, DHS. ACTION: Committee Management...

  20. Impacts of a participatory approach to developing national level sustainable development indicators in Finland.

    PubMed

    Rosenström, Ulla; Kyllönen, Simo

    2007-08-01

    The paper explores the role of a participatory approach in the outcome of the Finnish sustainable development indicator (SDI) exercise in 1998-2002. The process is analysed through three main objectives: to achieve stronger democracy, better quality of the end product and a more effective process. The analysis is further structured by a set of criteria needed for successful participation and differentiation of types of participants. The criteria comprise three main aspects: fairness, competence and social learning. In addition to the normally mentioned stakeholders (e.g. citizens and interest groups) participants also include experts and civil servants. Using the set of criteria above the participatory approach of the Finnish SDI process is then evaluated, and in the light of this evaluation the paper also discusses the specifications needed as evaluation criteria for national level policy programme processes like developing the SDIs. The results are based on documentation of the indicator task force meetings, written comments and a study of the putative end-users conducted after the publication of the indicators. The results show that the intense and broad participation of experts and civil servants increased the competence of the outcome and led to greater efficiency in working methods. However, this led to technocratic participation, absence of democratic participation and absence of social learning. Thus the ultimate goal of SDIs to contribute to achieving sustainability was not reached.

  1. National Institutes of Health addresses the science of diversity.

    PubMed

    Valantine, Hannah A; Collins, Francis S

    2015-10-06

    The US biomedical research workforce does not currently mirror the nation's population demographically, despite numerous attempts to increase diversity. This imbalance is limiting the promise of our biomedical enterprise for building knowledge and improving the nation's health. Beyond ensuring fairness in scientific workforce representation, recruiting and retaining a diverse set of minds and approaches is vital to harnessing the complete intellectual capital of the nation. The complexity inherent in diversifying the research workforce underscores the need for a rigorous scientific approach, consistent with the ways we address the challenges of science discovery and translation to human health. Herein, we identify four cross-cutting diversity challenges ripe for scientific exploration and opportunity: research evidence for diversity's impact on the quality and outputs of science; evidence-based approaches to recruitment and training; individual and institutional barriers to workforce diversity; and a national strategy for eliminating barriers to career transition, with scientifically based approaches for scaling and dissemination. Evidence-based data for each of these challenges should provide an integrated, stepwise approach to programs that enhance diversity rapidly within the biomedical research workforce.

  2. 9 CFR 130.11 - User fees for inspecting and approving import/export facilities and establishments.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... hourly user fee rate in § 130.30(2) applies to biosecurity level two laboratories. (b) [Reserved] [65 FR... approval) Per year $537.00 $553.00 $570.00 $587.00 $604.00 Inspection for approval of biosecurity level three labs (all inspections related to approving the laboratory for handling one defined set of...

  3. Biosecurity in the age of Big Data: a conversation with the FBI

    PubMed Central

    Kozminski, Keith G.

    2015-01-01

    New scientific frontiers and emerging technologies within the life sciences pose many global challenges to society. Big Data is a premier example, especially with respect to individual, national, and international security. Here a Special Agent of the Federal Bureau of Investigation discusses the security implications of Big Data and the need for security in the life sciences. PMID:26543195

  4. More than one rabbit out of the hat: Radiation, transgenic and symbiont-based approaches for sustainable management of mosquito and tsetse fly populations.

    PubMed

    Bourtzis, Kostas; Lees, Rosemary Susan; Hendrichs, Jorge; Vreysen, Marc J B

    2016-05-01

    Mosquitoes (Diptera: Culicidae) and tsetse flies (Diptera: Glossinidae) are bloodsucking vectors of human and animal pathogens. Mosquito-borne diseases (malaria, filariasis, dengue, zika, and chikungunya) cause severe mortality and morbidity annually, and tsetse fly-borne diseases (African trypanosomes causing sleeping sickness in humans and nagana in livestock) cost Sub-Saharan Africa an estimated US$ 4750 million annually. Current reliance on insecticides for vector control is unsustainable: due to increasing insecticide resistance and growing concerns about health and environmental impacts of chemical control there is a growing need for novel, effective and safe biologically-based methods that are more sustainable. The integration of the sterile insect technique has proven successful to manage crop pests and disease vectors, particularly tsetse flies, and is likely to prove effective against mosquito vectors, particularly once sex-separation methods are improved. Transgenic and symbiont-based approaches are in development, and more advanced in (particularly Aedes) mosquitoes than in tsetse flies; however, issues around stability, sustainability and biosecurity have to be addressed, especially when considering population replacement approaches. Regulatory issues and those relating to intellectual property and economic cost of application must also be overcome. Standardised methods to assess insect quality are required to compare and predict efficacy of the different approaches. Different combinations of these three approaches could be integrated to maximise their benefits, and all have the potential to be used in tsetse and mosquito area-wide integrated pest management programmes. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  5. The Roadmap: Future Opportunities for Bioengagement in the MENA Region

    DTIC Science & Technology

    2013-12-01

    research to improving biosafety and biosecurity training of laboratory staff, enhancing physical security of research and diagnostic facilities, and...enhancing laboratory and institutional capacity to address biological risks according to international standards ; or building scientific capacity...outbreaks. BEP often supports scientific exchanges to enhance laboratory biosafety and biosecurity training; it could enrich its efforts by

  6. Shrimp farming practices in the puttallam district of sri lanka: implications for disease control, industry sustainability, and rural development.

    PubMed

    Munasinghe, M Nalaka; Stephen, Craig; Abeynayake, Preeni; Abeygunawardena, Indra S

    2010-08-12

    Shrimp farming has great potential to diversify and secure income in rural Sri Lanka, but production has significantly declined in recent years due to civil conflicts, some unsustainable practices and devastating outbreaks of disease. We examined management practices affecting disease prevention and control in the Puttalam district to identify extension services outputs that could support sustainable development of Sri Lankan shrimp farming. A survey on 621 shrimp farms (603 operational and 18 nonoperational) was conducted within the Puttalam district over 42 weeks comprising a series of three-day field visits from August 2008 to October 2009, covering two consecutive shrimp crops. Fundamental deficits in disease control, management, and biosecurity practices were found. Farmers had knowledge of biosecurity but the lack of financial resources was a major impediment to improved disease control. Smallholder farmers were disproportionately constrained in their ability to enact basic biosecurity practices due to their economic status. Basic breaches in biosecurity will keep disease as the rate limiting step in this industry. Plans to support this industry must recognize the socioeconomic reality of rural Sri Lankan aquaculture.

  7. Shrimp Farming Practices in the Puttallam District of Sri Lanka: Implications for Disease Control, Industry Sustainability, and Rural Development

    PubMed Central

    Munasinghe, M. Nalaka; Stephen, Craig; Abeynayake, Preeni; Abeygunawardena, Indra S.

    2010-01-01

    Shrimp farming has great potential to diversify and secure income in rural Sri Lanka, but production has significantly declined in recent years due to civil conflicts, some unsustainable practices and devastating outbreaks of disease. We examined management practices affecting disease prevention and control in the Puttalam district to identify extension services outputs that could support sustainable development of Sri Lankan shrimp farming. A survey on 621 shrimp farms (603 operational and 18 nonoperational) was conducted within the Puttalam district over 42 weeks comprising a series of three-day field visits from August 2008 to October 2009, covering two consecutive shrimp crops. Fundamental deficits in disease control, management, and biosecurity practices were found. Farmers had knowledge of biosecurity but the lack of financial resources was a major impediment to improved disease control. Smallholder farmers were disproportionately constrained in their ability to enact basic biosecurity practices due to their economic status. Basic breaches in biosecurity will keep disease as the rate limiting step in this industry. Plans to support this industry must recognize the socioeconomic reality of rural Sri Lankan aquaculture. PMID:20847956

  8. Quantifying the Establishment Likelihood of Invasive Alien Species Introductions Through Ports with Application to Honeybees in Australia.

    PubMed

    Heersink, Daniel K; Caley, Peter; Paini, Dean R; Barry, Simon C

    2016-05-01

    The cost of an uncontrolled incursion of invasive alien species (IAS) arising from undetected entry through ports can be substantial, and knowledge of port-specific risks is needed to help allocate limited surveillance resources. Quantifying the establishment likelihood of such an incursion requires quantifying the ability of a species to enter, establish, and spread. Estimation of the approach rate of IAS into ports provides a measure of likelihood of entry. Data on the approach rate of IAS are typically sparse, and the combinations of risk factors relating to country of origin and port of arrival diverse. This presents challenges to making formal statistical inference on establishment likelihood. Here we demonstrate how these challenges can be overcome with judicious use of mixed-effects models when estimating the incursion likelihood into Australia of the European (Apis mellifera) and Asian (A. cerana) honeybees, along with the invasive parasites of biosecurity concern they host (e.g., Varroa destructor). Our results demonstrate how skewed the establishment likelihood is, with one-tenth of the ports accounting for 80% or more of the likelihood for both species. These results have been utilized by biosecurity agencies in the allocation of resources to the surveillance of maritime ports. © 2015 Society for Risk Analysis.

  9. Collaboration in national forest management

    Treesearch

    Susan Charnley; Jonathan W. Long; Frank K. Lake

    2014-01-01

    National forest management efforts have generally moved toward collaborative and participatory approaches at a variety of scales. This includes, at a larger scale, greater public participation in transparent and inclusive democratic processes and, at a smaller scale, more engagement with local communities. Participatory approaches are especially important for an all-...

  10. Nuclear Arms and National Security. 1983 National Issues Forum.

    ERIC Educational Resources Information Center

    Melville, Keith, Ed.

    Appropriate for secondary school social studies, this booklet outlines approaches for dealing with the threat of nuclear warfare in six sections. The first section, "Learning to Live with Nuclear Weapons," introduces the topic and considers what can be done to decrease the risk of nuclear warfare without jeopardizing the nation's security. "Arms…

  11. National visitor use monitoring implementation in Alaska.

    Treesearch

    Eric M. White; Joshua B. Wilson

    2008-01-01

    The USDA Forest Service implemented the National Visitor Use Monitoring (NVUM) program across the entire National Forest System (NFS) in calendar year 2000. The primary objective of the NVUM program is to develop reliable estimates of recreation use on NFS lands via a nationally consistent, statistically valid sampling approach. Secondary objectives of NVUM are to...

  12. Biological Risks to Public Health: Lessons from an International Conference to Inform the Development of National Risk Communication Strategies

    PubMed Central

    Bhatiasevi, Aphaluck; Chaib, Fadela; Baggio, Ombretta; Banluta, Christina; Hollenweger, Lilian; Maaroufi, Abderrahmane

    2016-01-01

    Biological risk management in public health focuses on the impact of outbreaks on health, the economy, and other systems and on ensuring biosafety and biosecurity. To address this broad range of risks, the International Health Regulations (IHR, 2005) request that all member states build defined core capacities, risk communication being one of them. While there is existing guidance on the communication process and on what health authorities need to consider to design risk communication strategies that meet the requirements on a governance level, little has been done on implementation because of a number of factors, including lack of resources (human, financial, and others) and systems to support effective and consistent capacity for risk communication. The international conference on “Risk communication strategies before, during and after public health emergencies” provided a platform to present current strategies, facilitate learning from recent outbreaks of infectious diseases, and discuss recommendations to inform risk communication strategy development. The discussion concluded with 4 key areas for improvement in risk communication: consider communication as a multidimensional process in risk communication, broaden the biomedical paradigm by integrating social science intelligence into epidemiologic risk assessments, strengthen multisectoral collaboration including with local organizations, and spearhead changes in organizations for better risk communication governance. National strategies should design risk communication to be proactive, participatory, and multisectoral, facilitating the connection between sectors and strengthening collaboration. PMID:27875654

  13. Biological Risks to Public Health: Lessons from an International Conference to Inform the Development of National Risk Communication Strategies.

    PubMed

    Dickmann, Petra; Bhatiasevi, Aphaluck; Chaib, Fadela; Baggio, Ombretta; Banluta, Christina; Hollenweger, Lilian; Maaroufi, Abderrahmane

    Biological risk management in public health focuses on the impact of outbreaks on health, the economy, and other systems and on ensuring biosafety and biosecurity. To address this broad range of risks, the International Health Regulations (IHR, 2005) request that all member states build defined core capacities, risk communication being one of them. While there is existing guidance on the communication process and on what health authorities need to consider to design risk communication strategies that meet the requirements on a governance level, little has been done on implementation because of a number of factors, including lack of resources (human, financial, and others) and systems to support effective and consistent capacity for risk communication. The international conference on "Risk communication strategies before, during and after public health emergencies" provided a platform to present current strategies, facilitate learning from recent outbreaks of infectious diseases, and discuss recommendations to inform risk communication strategy development. The discussion concluded with 4 key areas for improvement in risk communication: consider communication as a multidimensional process in risk communication, broaden the biomedical paradigm by integrating social science intelligence into epidemiologic risk assessments, strengthen multisectoral collaboration including with local organizations, and spearhead changes in organizations for better risk communication governance. National strategies should design risk communication to be proactive, participatory, and multisectoral, facilitating the connection between sectors and strengthening collaboration.

  14. Biological Terrorism: US Policies to Reduce Global Biothreats

    DTIC Science & Technology

    2008-09-01

    program for pro- jects that advance BEP objectives. Global Cooperation to develop bio- safety and pathogen security stan- dards that are consistent with...security. The Organization for Economic Cooperation and Development ( OECD ) has recently developed voluntary biosecurity guidelines for implementation...Abbreviations AG Australia Group BEP Biosecurity Engagement Program BSL Biosafety level BWC Biological Weapons Convention BWC-ISU Biological Weapons

  15. [THE CONDITION AND TENDENCIES OF DEVELOPMENT OF CLINICAL AND SANITARY MICROBIOLOGY IN THE RUSSIAN FEDERATION AND PROBLEM OF IMPORT SUBSTITUTION].

    PubMed

    Dyatlov, I A; Mironov, A Yu; Shepelin, A P; Aleshkin, V A

    2015-08-01

    The import substitution becomes one of the strategic tasks of national economy as a result of prolongation of economic sanctions concerning the Russian Federation of part of the USA, EU countries, Japan and number of other countries. It is not proper to be limited in import substitution only by goods because in conditions ofsanctions when access toforeign technologies is complicated Russia is needed to substitute foreign technologies by national designs in faster manner One of directions of effective import substitution is localization of production of laboratory equipment and consumables for clinical and sanitary microbiology on the territory ofthe Russian Federation and countries of Customs union. In Russia, in the field ofdiagnostic of dangerous and socially significant infections, all components for import substitution to implement gene diagnostic, immune diagnostic. bio-sensory and biochip approaches, isolation and storage of live microbial cultures, implementation of high-tech methods of diagnostic are available. At the same time, national diagnostic instrument-making industry for microbiology is factually absent. The few devices of national production more than on 50% consist of import components. The microbiological laboratories are to be equipped only with import devices of open type for applying national components. The most perspective national designs to be implemented are multiplex polimerase chain reaction test-systems and biochips on the basis of national plotters and readers. The modern development of diagnostic equipment and diagnostic instruments requires supplement of national collections of bacterial and viral pathogens and working-through of organizational schemes of supplying collections with strains. The presented data concerning justification of nomenclature of laboratory equipment and consumables permits to satisfy in fill scope the needs of clinical and sanitary microbiology in devices, growth mediums, consumables of national production

  16. The National Assessment Approach to Objectives and Exercise Development.

    ERIC Educational Resources Information Center

    Ward, Barbara

    The National Assessment of Educational Progress (NAEP) item development procedures, possible improvements or alternatives to these procedures, and methods used to control potential sources of errors of interpretation are described. Current procedures call for the assessment of 9-, 13- and 17-year-olds in subject areas typically taught in schools.…

  17. Developing a new, national approach to surveillance for ventilator-associated events*.

    PubMed

    Magill, Shelley S; Klompas, Michael; Balk, Robert; Burns, Suzanne M; Deutschman, Clifford S; Diekema, Daniel; Fridkin, Scott; Greene, Linda; Guh, Alice; Gutterman, David; Hammer, Beth; Henderson, David; Hess, Dean; Hill, Nicholas S; Horan, Teresa; Kollef, Marin; Levy, Mitchell; Septimus, Edward; VanAntwerpen, Carole; Wright, Don; Lipsett, Pamela

    2013-11-01

    To develop and implement an objective, reliable approach to surveillance for ventilator-associated events in adult patients. The Centers for Disease Control and Prevention (CDC) convened a Ventilator-Associated Pneumonia (VAP) Surveillance Definition Working Group in September 2011. Working Group members included representatives of stakeholder societies and organizations and federal partners. The Working Group finalized a three-tier, adult surveillance definition algorithm for ventilator-associated events. The algorithm uses objective, readily available data elements and can identify a broad range of conditions and complications occurring in mechanically ventilated adult patients, including but not limited to VAP. The first tier definition, ventilator-associated condition (VAC), identifies patients with a period of sustained respiratory deterioration following a sustained period of stability or improvement on the ventilator, defined by changes in the daily minimum fraction of inspired oxygen or positive end-expiratory pressure. The second tier definition, infection-related ventilator-associated complication (IVAC), requires that patients with VAC also have an abnormal temperature or white blood cell count, and be started on a new antimicrobial agent. The third tier definitions, possible and probable VAP, require that patients with IVAC also have laboratory and/or microbiological evidence of respiratory infection. Ventilator-associated events surveillance was implemented in January 2013 in the CDC's National Healthcare Safety Network. Modifications to improve surveillance may be made as additional data become available and users gain experience with the new definitions.

  18. Talent Development: Potential for Developing Nations.

    ERIC Educational Resources Information Center

    Harris, Carole Ruth

    1993-01-01

    A theoretical approach to talent development in emerging nations is proposed, based on principles of curricular intervention derived from qualitative research. Implementation of such a culturally appropriate curriculum in Ebeye, Marshall Islands, illustrates the approach. Adaptations to other cultures are suggested. (Author/DB)

  19. Novel approach to systematic random sampling in population surveys: Lessons from the United Arab Emirates National Diabetes Study (UAEDIAB).

    PubMed

    Sulaiman, Nabil; Albadawi, Salah; Abusnana, Salah; Fikri, Mahmoud; Madani, Abdulrazzag; Mairghani, Maisoon; Alawadi, Fatheya; Zimmet, Paul; Shaw, Jonathan

    2015-09-01

    The prevalence of diabetes has risen rapidly in the Middle East, particularly in the Gulf Region. However, some prevalence estimates have not fully accounted for large migrant worker populations and have focused on minority indigenous populations. The objectives of the UAE National Diabetes and Lifestyle Study are to: (i) define the prevalence of, and risk factors for, T2DM; (ii) describe the distribution and determinants of T2DM risk factors; (iii) study health knowledge, attitudes, and (iv) identify gene-environment interactions; and (v) develop baseline data for evaluation of future intervention programs. Given the high burden of diabetes in the region and the absence of accurate data on non-UAE nationals in the UAE, a representative sample of the non-UAE nationals was essential. We used an innovative methodology in which non-UAE nationals were sampled when attending the mandatory biannual health check that is required for visa renewal. Such an approach could also be used in other countries in the region. Complete data were available for 2719 eligible non-UAE nationals (25.9% Arabs, 70.7% Asian non-Arabs, 1.1% African non-Arabs, and 2.3% Westerners). Most were men < 65 years of age. The response rate was 68%, and the non-response was greater among women than men; 26.9% earned less than UAE Dirham (AED) 24 000 (US$6500) and the most common areas of employment were as managers or professionals, in service and sales, and unskilled occupations. Most (37.4%) had completed high school and 4.1% had a postgraduate degree. This novel methodology could provide insights for epidemiological studies in the UAE and other Gulf States, particularly for expatriates. © 2015 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Wiley Publishing Asia Pty Ltd.

  20. Implementation of an Integrated Approach to the National HIV/AIDS Strategy for Improving Human Immunodeficiency Virus Care for Youths.

    PubMed

    Fortenberry, J Dennis; Koenig, Linda J; Kapogiannis, Bill G; Jeffries, Carrie L; Ellen, Jonathan M; Wilson, Craig M

    2017-07-01

    Youths aged 13 to 24 years old living with human immunodeficiency virus (HIV) are less likely than adults to receive the health and prevention benefits of HIV treatments, with only a small proportion having achieved sustained viral suppression. These age-related disparities in HIV continuum of care are owing in part to the unique developmental issues of adolescents and young adults as well as the complexity and fragmentation of HIV care and related services. This article summarizes a national, multiagency, and multilevel approach to HIV care for newly diagnosed youths designed to bridge some of these fragmentations by addressing National HIV/AIDS Strategy goals for people living with HIV. Three federal agencies developed memoranda of understanding to sequentially implement 3 protocols addressing key National HIV/AIDS Strategy goals. The goals were addressed in the Adolescent Trials Network, with protocols implemented in 12 to 15 sites across the United States. Outcome data were collected from recently diagnosed youth referred to the program. Cross-agency collaboration, youth-friendly linkage to care services, community mobilization to address structural barriers to care, cooperation among services, proportion of all men who have sex with men who tested, and rates of linkage to prevention services. The program addressed National HIV/AIDS Strategy goals 2 through 4 including steps within each goal. A total of 3986 HIV-positive youths were referred for care, with more than 75% linked to care within 6 weeks of referral, with almost 90% of those youths engaged in subsequent HIV care. Community mobilization efforts implemented and completed structural change objectives to address local barriers to care. Age and racial/ethnic group disparities were addressed through targeted training for culturally competent, youth-friendly care, and intensive motivational interviewing training. A national program to address the National HIV/AIDS Strategy specifically for youths can

  1. National Response Framework (NRF)

    EPA Pesticide Factsheets

    The NRF establishes a single, comprehensive approach to domestic incident management to prevent, prepare for, respond to, and recover from terrorist attacks, major disasters, and other emergencies. Built on the National Incident Management System template.

  2. What should health insurance cover? A comparison of Israeli and US approaches to benefit design under national health reform.

    PubMed

    Nissanholtz Gannot, Rachel; Chinitz, David P; Rosenbaum, Sara

    2018-04-01

    What health insurance should cover and pay for represents one of the most complex questions in national health policy. Israel shares with the US reliance on a regulated insurance market and we compare the approaches of the two countries regarding determining health benefits. Based on review and analysis of literature, laws and policy in the United States and Israel. The Israeli experience consists of selection of a starting point for defining coverage; calculating the expected cost of covered benefits; and creating a mechanism for updating covered benefits within a defined budget. In implementing the Affordable Care Act, the US rejected a comprehensive and detailed approach to essential health benefits. Instead, federal regulators established broadly worded minimum standards that can be supplemented through more stringent state laws and insurer discretion. Notwithstanding differences between the two systems, the elements of the Israeli approach to coverage, which has stood the test of time, may provide a basis for the United States as it renews its health reform debate and considers delegating decisions about coverage to the states. Israel can learn to emulate the more forceful regulation of supplemental and private insurance that characterizes health policy in the United States.

  3. The relation between societal factors and different forms of prejudice: A cross-national approach on target-specific and generalized prejudice.

    PubMed

    Meeusen, Cecil; Kern, Anna

    2016-01-01

    The goal of this paper was to investigate the generalizability of prejudice across contexts by analyzing associations between different types of prejudice in a cross-national perspective and by investigating the relation between country-specific contextual factors and target-specific prejudices. Relying on the European Social Survey (2008), results indicated that prejudices were indeed positively associated, confirming the existence of a generalized prejudice component. Next to substantial cross-national differences in associational strength, also within country variance in target-specific associations was observed. This suggested that the motivations for prejudice largely vary according to the intergroup context. Two aspects of the intergroup context - economic conditions and cultural values - showed to be related to generalized and target-specific components of prejudice. Future research on prejudice and context should take an integrative approach that considers both the idea of generalized and specific prejudice simultaneously. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Impact of avian influenza on village poultry production globally.

    PubMed

    Alders, Robyn; Awuni, Joseph Adongo; Bagnol, Brigitte; Farrell, Penny; de Haan, Nicolene

    2014-01-01

    Village poultry and their owners were frequently implicated in disease transmission in the early days of the highly pathogenic avian influenza (HPAI) H5N1 pandemic. With improved understanding of the epidemiology of the disease, it was recognized that village poultry raised under extensive conditions pose less of a threat than intensively raised poultry of homogeneous genetic stock with poor biosecurity. This paper provides an overview of village poultry production and the multiple ways that the HPAI H5N1 pandemic has impacted on village poultry, their owners, and the traders whose livelihoods are intimately linked to these birds. It reviews impact in terms of gender and cultural issues; food security; village poultry value chains; approaches to biosecurity; marketing; poultry disease prevention and control; compensation; genetic diversity; poultry as part of livelihood strategies; and effective communication. It concludes on a positive note that there is growing awareness amongst animal health providers of the importance of facilitating culturally sensitive dialogue to develop HPAI prevention and control options.

  5. H5N1 influenza viruses: facts, not fear.

    PubMed

    Palese, Peter; Wang, Taia T

    2012-02-14

    The ongoing controversy over publication of two studies involving the transmission in ferrets of H5N1 (H5) subtype influenza viruses and the recommendations of the National Science Advisory Board for Biosecurity to redact key details in the manuscripts call for an examination of relevant scientific facts. In addition, there are calls in the media to destroy the viruses, curtail future research in this area, and protect the public from such "frightening" research efforts. Fear needs to be put to rest with solid science and not speculation.

  6. Effects of relational uncertainty in heightening national identification and reactive approach motivation of Japanese.

    PubMed

    Terashima, Yuto; Takai, Jiro

    2017-03-23

    This study investigated whether relational uncertainty poses uncertainty threat, which causes compensatory behaviours among Japanese. We hypothesised that Japanese, as collectivists, would perceive relational uncertainty to pose uncertainty threat. In two experiments, we manipulated relational uncertainty, and confirmed that participants exhibited compensatory reactions to reduce aversive feelings due to it. In Study 1, we conducted direct comparison between relational uncertainty, independent self-uncertainty and control conditions. The results revealed that participants who were instructed to imagine events pertaining to relational uncertainty heightened national identification as compensation than did participants in the control condition, but independent self-uncertainty did not provoke such effects. In Study 2, we again manipulated relational uncertainty; however, we also manipulated participants' individualism-collectivism cultural orientation through priming, and the analyses yielded a significant interaction effect between these variables. Relational uncertainty evoked reactive approach motivation, a cause for compensatory behaviours, among participants primed with collectivism, but not for individualism. It was concluded that the effect of uncertainty on compensatory behaviour is influenced by cultural priming, and that relational uncertainty is important to Japanese. © 2017 International Union of Psychological Science.

  7. Engineering Approaches to Energy Balance and Obesity: Opportunities for Novel Collaborations and Research: Report of a Joint National Science Foundation and National Institutes of Health Workshop

    PubMed Central

    Ershow, Abby G.; Ortega, Alfonso; Timothy Baldwin, J.; Hill, James O.

    2007-01-01

    Energy balance disorders account for a large public health burden. The obesity epidemic in particular is one of the most rapidly evolving public health problems of our day. At present, two-thirds of American adults and one-sixth of American children and adolescents are considered either overweight or obese. Public health concern about obesity is high because of the increased risk and increased mortality of cardiovascular disease, Type 2 diabetes, many forms of cancer, gallbladder disease, and osteoarthritis. These risks increase with the severity of the obesity. Excess adipose tissue, representing fat storage, ultimately derives from an imbalance between energy intake and energy expenditure. Conversely, undesirable and inadvertent loss of body weight and muscle mass, as seen in aging and cachectic states of chronic diseases such as heart failure and cancer, have serious clinical and functional consequences without satisfactory clinical or behavioral solutions. Innovative engineering technologies could help to address unresolved problems in energy balance, intake, and expenditure. Novel sensors, devices, imaging technologies, nanotechnologies, biomaterials, technologies to detect biochemical markers of energy balance, mathematical modeling, systems biology, and other approaches could be developed, evaluated, and leveraged through multidisciplinary collaborations. Engineers, physical scientists, and mathematicians can work with scientists from other relevant disciplines who possess expertise in obesity and nutrition. Furthermore, the possibility of re-engineering the “built environment” to encourage higher levels of physical activity has been suggested as another promising and important approach to which engineers can contribute (see http://www.obesityresearch.nih.gov). Ultimately, systematic application of the “Engineering Approach” can help in developing the needed technologies and tools to facilitate research and eventually support therapeutic advances and

  8. Farm-economic analysis of reducing antimicrobial use whilst adopting improved management strategies on farrow-to-finish pig farms.

    PubMed

    Rojo-Gimeno, Cristina; Postma, Merel; Dewulf, Jeroen; Hogeveen, Henk; Lauwers, Ludwig; Wauters, Erwin

    2016-07-01

    Due to increasing public health concerns that food animals could be reservoirs for antibiotic resistant organisms, calls for reduced current antibiotic use on farms are growing. Nevertheless, it is challenging for farmers to perform this reduction without negatively affecting technical and economic performance. As an alternative, improved management practices based on biosecurity and vaccinations have been proven useful to reduce antimicrobial use without lowering productivity, but issues with insufficient experimental design possibilities have hindered economic analysis. In the present study a quasi-experimental approach was used for assessing the economic impact of reduction of antimicrobial use coupled with improved management strategies, particularly biosecurity strategies. The research was performed on farrow-to-finish pig farms in Flanders (northern region of Belgium). First, to account for technological progress and to avoid selection bias, propensity score analysis was used to compare data on technical parameters. The treatment group (n=48) participated in an intervention study whose aim was to improve management practices to reduce the need for use of antimicrobials. Before and after the change in management, data were collected on the technical parameters, biosecurity status, antimicrobial use, and vaccinations. Treated farms were matched without replacement with control farms (n=69), obtained from the Farm Accountancy Data Network, to estimate the difference in differences (DID) of the technical parameters. Second, the technical parameters' DID, together with the estimated costs of the management intervention and the price volatility of the feed, meat of the finisher pigs, and piglets served as a basis for modelling the profit of 11 virtual farrow-to-finish pig farms representative of the Flemish sector. Costs incurred by new biosecurity measures (median +€3.96/sow/year), and new vaccinations (median €0.00/sow/year) did not exceed the cost reduction

  9. Investigating the financial impact of porcine reproductive and respiratory syndrome on smallholder pig farmers in Cambodia.

    PubMed

    Zhang, A; Young, J R; Suon, S; Ashley, K; Windsor, P A; Bush, R D

    2017-04-01

    Porcine reproductive and respiratory syndrome (PRRS) was first identified in Cambodia in 2010, causing serious problems on affected farms, although the costs of the disease have not been well defined. The household financial impact of a PRRS outbreak in Cambodia was investigated using partial budget analysis, examining the economic benefit of three proposed interventions: (i) quarterly PRRS vaccine use, (ii) biosecurity implementation, and (iii) implementation of vaccination and biosecurity. The analyses were applied to three farm models: (i) a two-sow breeder; (ii) a five-pig fattener; and (iii) a single-sow, three-pig farrow-to-finish/breeder. Data was derived from a knowledge, attitude, and practice survey of 240 smallholder farmers (61 with pigs) from 16 villages across 5 provinces, plus case studies of 12 farmers selected for more detailed financial analysis. The study indicated that financial losses associated with PRRS were severe, with a 25% mean loss to the annual household income of 61 interviewed farmers. Partial budget analysis identified a strongly positive incentive for vaccination and biosecurity to be implemented in combination, with the highest annual net benefit of USD 357.10 realised by the breeder system. However, due to current scarcity of the PRRS vaccine and its high cost to smallholders, biosecurity interventions may be more cost-effective, especially for low PRRS incidence regions. It was concluded that PRRS critically constrains the profitability of smallholder pig farms and that these findings will assist development of village-level livestock disease risk management programmes that encourage adoption of vaccination and biosecurity practices to enhance farmer livelihoods in Cambodia.

  10. A Biosecurity Checklist for School Foodservice Programs: Developing a Biosecurity Management Plan

    ERIC Educational Resources Information Center

    US Department of Agriculture, 2004

    2004-01-01

    The purpose of this document is to introduce the need for securing foodservice operations from bioterrorism, provide a checklist of suggestions for improving the security of foodservice operations, and assist individuals responsible for school food service programs in strengthening the safety of the foodservice operation. While not mandatory, the…

  11. Chemical decontamination technical resources at Los Alamos National Laboratory (2008)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moore, Murray E

    This document supplies information resources for a person seeking to create planning or pre-planning documents for chemical decontamination operations. A building decontamination plan can be separated into four different sections: Pre-planning, Characterization, Decontamination (Initial response and also complete cleanup), and Clearance. Of the identified Los Alamos resources, they can be matched with these four sections: Pre-planning -- Dave Seidel, EO-EPP, Emergency Planning and Preparedness; David DeCroix and Bruce Letellier, D-3, Computational fluids modeling of structures; Murray E. Moore, RP-2, Aerosol sampling and ventilation engineering. Characterization (this can include development projects) -- Beth Perry, IAT-3, Nuclear Counterterrorism Response (SNIPER database); Fernandomore » Garzon, MPA-11, Sensors and Electrochemical Devices (development); George Havrilla, C-CDE, Chemical Diagnostics and Engineering; Kristen McCabe, B-7, Biosecurity and Public Health. Decontamination -- Adam Stively, EO-ER, Emergency Response; Dina Matz, IHS-IP, Industrial hygiene; Don Hickmott, EES-6, Chemical cleanup. Clearance (validation) -- Larry Ticknor, CCS-6, Statistical Sciences.« less

  12. BioWatch: Case for Change of Traditional Leadership to Improve Performance

    DTIC Science & Technology

    2009-09-01

    in New Jersey, a nurse in New York City, and an elderly widow in rural Connecticut—also caught anthrax. The nurse and the widow died.26 The...36 Daniel M. Sosin, “Syndromic Surveillance: The Case for Skillful Investment,” Biosecurity and Bioterrorism: Biodefense...Report no. 35, October 2000. Sosin, Daniel M. “Syndromic Surveillance: The Case for Skillful Investment.” Biosecurity and Bioterrorism: Biodefense

  13. National Ocean Sciences Bowl in 2013: A National Competition for High School Ocean Science Education

    DTIC Science & Technology

    2013-09-30

    The school even has begun to list oceanography as an extracurricular activity in its advertisements! I have seen firsthand how NOSB has raised an...event at the NOSB Finals; • Develop a career booklet to help guide students selecting a career related to ocean sciences; and • Actively encourage...students from diverse communities to participate in NOSB activities . APPROACH The National Ocean Sciences Bowl® (NOSB ®) is a nationally

  14. A direct sensitivity approach to predict hourly ozone resulting from compliance with the National Ambient Air Quality Standard.

    PubMed

    Simon, Heather; Baker, Kirk R; Akhtar, Farhan; Napelenok, Sergey L; Possiel, Norm; Wells, Benjamin; Timin, Brian

    2013-03-05

    In setting primary ambient air quality standards, the EPA's responsibility under the law is to establish standards that protect public health. As part of the current review of the ozone National Ambient Air Quality Standard (NAAQS), the US EPA evaluated the health exposure and risks associated with ambient ozone pollution using a statistical approach to adjust recent air quality to simulate just meeting the current standard level, without specifying emission control strategies. One drawback of this purely statistical concentration rollback approach is that it does not take into account spatial and temporal heterogeneity of ozone response to emissions changes. The application of the higher-order decoupled direct method (HDDM) in the community multiscale air quality (CMAQ) model is discussed here to provide an example of a methodology that could incorporate this variability into the risk assessment analyses. Because this approach includes a full representation of the chemical production and physical transport of ozone in the atmosphere, it does not require assumed background concentrations, which have been applied to constrain estimates from past statistical techniques. The CMAQ-HDDM adjustment approach is extended to measured ozone concentrations by determining typical sensitivities at each monitor location and hour of the day based on a linear relationship between first-order sensitivities and hourly ozone values. This approach is demonstrated by modeling ozone responses for monitor locations in Detroit and Charlotte to domain-wide reductions in anthropogenic NOx and VOCs emissions. As seen in previous studies, ozone response calculated using HDDM compared well to brute-force emissions changes up to approximately a 50% reduction in emissions. A new stepwise approach is developed here to apply this method to emissions reductions beyond 50% allowing for the simulation of more stringent reductions in ozone concentrations. Compared to previous rollback methods, this

  15. Education and Outreach in the Life Sciences: Qualitative Analysis Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Burbank, Roberta L.; John, Lisa; Mahy, Heidi A.

    The DOE's National Nuclear Security Agency (NNSA) asked Pacific Northwest National Laboratory (PNNL) to consider the role of individual scientists in upholding safety and security. The views of scientists were identified as being a critical component of this policy process. Therefore, scientists, managers, and representatives of Institutional Biosafety Committees (IBCs) at the national labs were invited to participate in a brief survey and a set of focus groups. In addition, three focus groups were conducted with scientists, managers, and IBC representatives to discuss some of the questions related to education, outreach, and codes of conduct in further detail and gathermore » additional input on biosecurity and dual-use awareness at the laboratories. The overall purpose of this process was to identify concerns related to these topics and to gather suggestions for creating an environment where both the scientific enterprise and national security are enhanced.« less

  16. Public health works: blood donation in urban China.

    PubMed

    Adams, Vincanne; Erwin, Kathleen; Le, Phuoc V

    2009-02-01

    Recent shifts in the global health infrastructure warrant consideration of the value and effectiveness of national public health campaigns. These shifts include the globalization of pharmaceutical research, the rise of NGO-funded health interventions, and the rise of biosecurity models of international health. We argue that although these trends have arisen as worthwhile responses to actual health needs, it is important to remember the key role that public health campaigns can play in the promotion of national health, especially in developing nations. Focusing on an example set by China in response to a public health crisis surrounding the national need for a clean and adequate blood supply and the inadvertent spread of HIV by way of blood donation in the early 1990's, we argue that there is an important role for strong national public health programs. We also identify the key factors that enabled China's response to this burgeoning epidemic to be, in the end, largely successful.

  17. Public Health Works: Blood Donation in Urban China

    PubMed Central

    Adams, Vincanne; Erwin, Kathleen; Le, Phuoc V

    2009-01-01

    Recent shifts in the global health infrastructure warrant consideration of the value and effectiveness of national public health campaigns. These shifts include the globalization of pharmaceutical research, the rise of NGO-funded health interventions, and the rise of biosecurity models of international health. We argue that although these trends have arisen as worthwhile responses to actual health needs, it is important to remember the key role that public health campaigns can play in the promotion of national health, especially in developing nations. Focusing on an example set by China in response to a public health crisis surrounding the national need for a clean and adequate blood supply and the inadvertent spread of HIV by way of blood donation in the early 19902, we argue that there is an important role for strong national public health programs. We also identify the key factors that enabled China’s response to this bourgeoning epidemic to be, in the end, largely successful. PMID:19058887

  18. Area contact networks and the spatio-temporal spread of infectious salmon anemia virus (ISAV) in Chile.

    PubMed

    Gustafson, L; Remmenga, M; Sandoval Del Valle, O; Ibarra, R; Antognoli, M; Gallardo, A; Rosenfeld, C; Doddis, J; Enriquez Sais, R; Bell, E; Lara Fica, M

    2016-03-01

    Area management, the coordination of production and biosecurity practices across neighboring farms, is an important disease control strategy in aquaculture. Area management in aquaculture escalated in prominence in response to outbreaks of infectious salmon anemia (ISA) internationally. Successes in disease control have been attributed to the separation achieved through area-level synchronized stocking, fallowing, movement restrictions, and fomite or pest control. Area management, however, is costly; often demanding extra biosecurity, lengthy or inconveniently timed fallows, and localization of equipment, personnel, and services. Yet, this higher-order organizational structure has received limited epidemiologic attention. Chile's National Fisheries and Aquaculture Service instigated area management practices in response to the 2007 emergence of ISA virus (ISAV). Longitudinal data simultaneously collected allowed retrospective evaluation of the impact of component tenets on virus control. Spatiotemporal analyses identified hydrographic linkages, shared ports, and fish transfers from areas with recent occurrence of ISAV as the strongest predictors of virus spread between areas, though specifics varied by ISAV type (here categorized as HPR0 for the non-virulent genotypes, and HPRv otherwise). Hydrographic linkages were most predictive in the period before implementation of enhanced biosecurity and fallowing regulations, suggesting that viral load can impact spread dynamics. HPR0 arose late in the study period, so few HPRv events were available by which to explore the hypothesis of HPR0 as progenitor of outbreaks. However, spatiotemporal patterns in HPRv occurrence were predictive of subsequent patterns in HPR0 detection, suggesting a parallel, or dependent, means of spread. Better data precision, breadth and consistency, common challenges for retrospective studies, could improve model fit; and, for HPR0, specification of diagnostic test accuracy would improve

  19. Malaysia implements the integrated approach.

    PubMed

    1977-01-01

    Malaysia has implemented an integrated approach in providing family planning services to eligible couples. In 1964 the government of Malaysia adopted a national family planning program, and implementation began in the urban areas and extended into the rural areas. Other agencies are involved in providing family planning services and information including the Federation of Family Planning Associations, the Ministry of Health, the National Family Planning Board, and the Federal Land Development Authority. The number of women practicing contraception has increased from 20,726 in 1967 to 533,646 by 1976. and other methods, 3.9%, respectively. There has been an increase in the percentage of acceptors between ages 15-29 from 56% in 1968 to 71.3% in 1975. The 2nd Malaysian national plan will use a multidisciplinary approach to the problem.

  20. The drivers of sea lice management policies and how best to integrate them into a risk management strategy: An ecosystem approach to sea lice management.

    PubMed

    Jackson, D; Moberg, O; Stenevik Djupevåg, E M; Kane, F; Hareide, H

    2018-06-01

    The control of sea lice infestations on cultivated Atlantic salmon is a major issue in many regions of the world. The numerous drivers which shape the priorities and objectives of the control strategies vary for different regions/jurisdictions. These range from the animal welfare and economic priorities of the producers, to the mitigation of any potential impacts on wild stocks. Veterinary ethics, environmental impacts of therapeutants, and impacts for organic certification of the produce are, amongst others, additional sets of factors which should be considered. Current best practice in both EU and international environmental law advocates a holistic ecosystem approach to assessment of impacts and risks. The issues of biosecurity and ethics, including the impacts on the stocks of species used as cleaner fish, are areas for inclusion in such a holistic ecosystem assessment. The Drivers, Pressures, State, Impacts, Responses (DPSIR) process is examined as a decision-making framework and potential applications to sea lice management are outlined. It is argued that this is required to underpin any integrated sea lice management (ISLM) strategy to balance pressures and outcomes and ensure a holistic approach to managing the issue of sea lice infestations on farmed stock on a medium to long-term basis. © 2017 The Authors. Journal of Fish Diseases Published by John Wiley & Sons Ltd.

  1. Theme--The Supervisor: Local, State and National.

    ERIC Educational Resources Information Center

    Barrick, R. Kirby; And Others

    1985-01-01

    The role of the local, state, and national supervisor is explored in these six articles. Specifically, they discuss changes in the supervisor's role, a team approach to national leadership, responsibilities of state supervisors, the role of the state supervisor, qualifications needed by a supervisor, and the local agriculture education supervisor.…

  2. Different approaches to the tasks of educating and training information systems professionals, within the National Health Service (UK).

    PubMed

    Grant, R M; Horkin, E J; Melhuish, P J; Norris, A C

    1998-06-01

    In 1994, La Sainte Union College of Higher Education (LSU) developed an MSc in Health Informatics course, in conjunction with Southampton University NHS Trust (SUHT). The original part-time, 1 day per week mode of delivery has since been broadened to include a distance leaning route and recently a block release mode, by which students combine usage of the distance learning materials with attendance in College for an intensive 2-day taught element. Because the course was designed in close co-operation with a major teaching hospital, it has always been 'market led' to meet the needs both of the individual students and of the organisations that they work for. At the same time, students acquire a quality-assured qualification from a premier UK university, a qualification that holds credence outside the National Health Service (NHS). At the same time as LSU and SUHT were developing the MSc in Health Informatics, the UK NHS Training Division (NHSTD) started to promote a professional qualification for health service professionals. the so-called 'Statement of Recognition' (SoR). In contrast to the academic format of an MSc, the SoR was not a formal course, but a combination of modules designed to help candidates demonstrate their competence and achievement at work by portfolio evidence. This approach has national standing throughout the UK in a set of qualifications known as NVQs (National Vocational Qualifications). The NHSTD, through its successor, the Institute of Health Care Development (IHCD), has further refined this competency based model, culminating in the launch in 1996 of the Diploma and Advanced Diploma in Information and Technology (Health). Professionals within the area of Information Management and Technology (IM&T) in the NHS now have the alternatives of an academic or a competency route to achieve their goals. This paper traces the development of and the relationship between, these two approaches to the educational and training of healthcare professionals

  3. Two approaches for incorporating climate change into natural resource management planning at Wind Cave National Park

    USGS Publications Warehouse

    Symstad, Amy J.; Long, Andrew J.; Stamm, John; King, David A.; Bachelet, Dominque M.; Norton, Parker A.

    2014-01-01

    Wind Cave National Park (WICA) protects one of the world’s longest caves, has large amounts of high quality, native vegetation, and hosts a genetically important bison herd. The park’s relatively small size and unique purpose within its landscape requires hands-on management of these and other natural resources, all of which are interconnected. Anthropogenic climate change presents an added challenge to WICA natural resource management because it is characterized by large uncertainties, many of which are beyond the control of park and National Park Service (NPS) staff. When uncertainty is high and control of this uncertainty low, scenario planning is an appropriate tool for determining future actions. In 2009, members of the NPS obtained formal training in the use of scenario planning in order to evaluate it as a tool for incorporating climate change into NPS natural resource management planning. WICA served as one of two case studies used in this training exercise. Although participants in the training exercise agreed that the scenario planning process showed promise for its intended purpose, they were concerned that the process lacked the scientific rigor necessary to defend the management implications derived from it in the face of public scrutiny. This report addresses this concern and others by (1) providing a thorough description of the process of the 2009 scenario planning exercise, as well as its results and management implications for WICA; (2) presenting the results of a follow-up, scientific study that quantitatively simulated responses of WICA’s hydrological and ecological systems to specific climate projections; (3) placing these climate projections and the general climate scenarios used in the scenario planning exercise in the broader context of available climate projections; and (4) comparing the natural resource management implications derived from the two approaches. Wind Cave National Park (WICA) protects one of the world’s longest caves

  4. A zone-based approach to identifying urban land uses using nationally-available data

    NASA Astrophysics Data System (ADS)

    Falcone, James A.

    Accurate identification of urban land use is essential for many applications in environmental study, ecological assessment, and urban planning, among other fields. However, because physical surfaces of land cover types are not necessarily related to their use and economic function, differentiating among thematically-detailed urban land uses (single-family residential, multi-family residential, commercial, industrial, etc.) using remotely-sensed imagery is a challenging task, particularly over large areas. Because the process requires an interpretation of tone/color, size, shape, pattern, and neighborhood association elements within a scene, it has traditionally been accomplished via manual interpretation of aerial photography or high-resolution satellite imagery. Although success has been achieved for localized areas using various automated techniques based on high-spatial or high-spectral resolution data, few detailed (Anderson Level II equivalent or greater) urban land use mapping products have successfully been created via automated means for broad (multi-county or larger) areas, and no such product exists today for the United States. In this study I argue that by employing a zone-based approach it is feasible to map thematically-detailed urban land use classes over large areas using appropriate combinations of non-image based predictor data which are nationally and publicly available. The approach presented here uses U.S. Census block groups as the basic unit of geography, and predicts the percent of each of ten land use types---nine of them urban---for each block group based on a number of data sources, to include census data, nationally-available point locations of features from the USGS Geographic Names Information System, historical land cover, and metrics which characterize spatial pattern, context (e.g. distance to city centers or other features), and measures of spatial autocorrelation. The method was demonstrated over a four-county area surrounding the

  5. National Drug Control Strategy. 2008 Annual Report

    ERIC Educational Resources Information Center

    Office of National Drug Control Policy, 2008

    2008-01-01

    This report presents the 2008 National Drug Control Strategy of the White House Office of National Drug Control Policy. The overarching goal of the President's Strategy is to reduce drug use in America through a balanced approach that focuses on stopping use before it starts, healing America's drug users, and disrupting the market for illegal…

  6. Placing Families in Context: Challenges for Cross-National Family Research

    PubMed Central

    Yu, Wei-hsin

    2015-01-01

    Cross-national comparisons constitute a valuable strategy to assess how broader cultural, political, and institutional contexts shape family outcomes. One typical approach of cross-national family research is to use comparable data from a limited number of countries, fit similar regression models for each country, and compare results across country-specific models. Increasingly, researchers are adopting a second approach, which requires merging data from many more societies and testing multilevel models using the pooled sample. Although the second approach has the advantage of allowing direct estimates of the effects of nation-level characteristics, it is more likely to suffer from the problems of omitted-variable bias, influential cases, and measurement and construct nonequivalence. I discuss ways to improve the first approach's ability to infer macrolevel influences, as well as how to deal with challenges associated with the second one. I also suggest choosing analytical strategies according to whether the data meet multilevel models’ assumptions. PMID:25999603

  7. The 2011 United Nations high-level meeting on non-communicable diseases: the Africa agenda calls for a 5-by-5 approach.

    PubMed

    Mensah, G A; Mayosi, B M

    2012-11-08

    The High Level Meeting of the 66th Session of the United Nations General Assembly was held in September 2011. The Political Declaration issued at the meeting focused the attention of world leaders and the global health community on the prevention and control of noncommunicable diseases (NCDs). The four major NCDs (cardiovascular diseases, cancer, diabetes and chronic respiratory diseases) and their four risk factors (tobacco use, unhealthy diet, physical inactivity and harmful use of alcohol) constitute the target of the '4-by-4' approach, which is also supported by national and international health organisations. We argue that while preventing these eight NCDs and risk factors is also important in Africa, it will not be enough. A '5-by-5' strategy is needed, addressing neuropsychiatric disorders as the fifth NCD; and transmissible agents that underlie the neglected tropical diseases and other NCDs as the fifth risk factor. These phenomena cause substantial preventable death and disability, and must therefore be prioritised.

  8. African swine fever control and market integration in Ugandan peri-urban smallholder pig value chains: An ex-ante impact assessment of interventions and their interaction.

    PubMed

    Ouma, Emily; Dione, Michel; Birungi, Rosemirta; Lule, Peter; Mayega, Lawrence; Dizyee, Kanar

    2018-03-01

    Pig production in peri-urban smallholder value chains in Uganda is severely constrained by impact of disease, particularly African swine fever (ASF), and the economic consequences of an inefficient pig value chain. Interventions in the form of biosecurity to control ASF disease outbreaks and pig business hub models to better link smallholder farmers to pig markets have the potential to address the constraints. However, there is a dearth of evidence of the effects of the interventions on performance and distribution of outcomes along the pig value chain. An ex-ante impact assessment utilising System Dynamics model was used to assess the impact of the interventions in peri-urban pig value chains in Masaka district. The results showed that although implementation of biosecurity interventions results in reduction of ASF outbreaks, it also leads to a 6.3% reduction in farmer profit margins per year but more than 7% increase in other value chain actors' margins. The pig business hub intervention alone results in positive margins for all value chain actors but minimal reduction in ASF outbreaks. When biosecurity and the pig business hub interventions are implemented together, the interaction effects of the interventions result in positive outcomes for both the control of ASF and improvement in farmers' margins. Farmers may therefore be unwilling to adopt biosecurity practices if implemented alone to control ASF outbreaks unless there is a corresponding financial incentive to compensate for the high costs. This has implications for policy or developing institutions to facilitate cost sharing arrangement among chain actors and/or third party subsidy to provide incentives for producers to adopt biosecurity measures. Copyright © 2017 The Authors. Published by Elsevier B.V. All rights reserved.

  9. Biosafety Initiatives in BMENA Region: Identification of Gaps and Advances.

    PubMed

    Khan, Erum; Ahmed, Nayla; Temsamani, Khalid R; El-Gendy, Atef; Cohen, Murray; Hasan, Ariba; Gastfriend, Hilliard; Cole, Jennifer

    2016-01-01

    The objectives of this study were to identify and assess the impact of capacity-building biosafety initiatives and programs that have taken place in the broader Middle East and North Africa (BMENA) region between 2001 and 2013, to highlight gaps that require further development, and to suggest sustainable ways to build cooperative regional biosafety opportunities. A cross-sectional study was conducted with two aspects (1) thorough desktop review of literature for all biosafety/biosecurity-related activities in the study countries, such as seminars, conferences, workshops, policy documents, technology transfer, sustained scientific endeavors between countries, etc. and (2) an online survey of scientists in countries in the region to get first-hand information about biosafety and biosecurity initiatives and gaps in their country. A total of 1832 initiatives of biosafety/biosecurity were recorded from 97 web links; 70.68% (n = 1295) initiatives were focused on raising general awareness among the scientific community about biosafety/biosecurity/biocontainment. The most frequent areas of interest were biorisk management in biomedical and biotechnology laboratories 13% (n = 239), followed by living modified organisms (LMOs) 9.17% (n = 168). Hands-on training accounted for 2.67% (n = 49) of initiatives. Online survey results confirmed desktop review findings; however, the response rate was 11%.

  10. 75 FR 64148 - General Regulation: National Park System

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-10-19

    ... acres. The smallest unit of the National Park System is Thaddeus Kosciuszko National Memorial... long-standing beliefs by volunteering not to approach or walk under the bridge. Equally important, the..., imposed a limitation on how long a permit may be issued (although allowing extensions), and provided the...

  11. Estimating Suicide Rates in Developing Nations: A Low-Cost Newspaper Capture-Recapture Approach in Cambodia.

    PubMed

    Harris, Keith M; Thandrayen, Joanne; Samphoas, Chien; Se, Pros; Lewchalermwongse, Boontriga; Ratanashevorn, Rattanakorn; Perry, Megan L; Britts, Choloe

    2016-04-01

    This study tested a low-cost method for estimating suicide rates in developing nations that lack adequate statistics. Data comprised reported suicides from Cambodia's 2 largest newspapers. Capture-recapture modeling estimated a suicide rate of 3.8/100 000 (95% CI = 2.5-6.7) for 2012. That compares to World Health Organization estimates of 1.3 to 9.4/100 000 and a Cambodian government estimate of 3.5/100 000. Suicide rates of males were twice that of females, and rates of those <40 years were twice that of those ≥40 years. Capture-recapture modeling with newspaper reports proved a reasonable method for estimating suicide rates for countries with inadequate official data. These methods are low-cost and can be applied to regions with at least 2 newspapers with overlapping reports. Means to further improve this approach are discussed. These methods are applicable to both recent and historical data, which can benefit epidemiological work, and may also be applicable to homicides and other statistics. © 2016 APJPH.

  12. Local distributions of wealth to describe health inequalities in India: a new approach for analyzing nationally representative household survey data, 1992-2008.

    PubMed

    Bassani, Diego G; Corsi, Daniel J; Gaffey, Michelle F; Barros, Aluisio J D

    2014-01-01

    Worse health outcomes including higher morbidity and mortality are most often observed among the poorest fractions of a population. In this paper we present and validate national, regional and state-level distributions of national wealth index scores, for urban and rural populations, derived from household asset data collected in six survey rounds in India between 1992-3 and 2007-8. These new indices and their sub-national distributions allow for comparative analyses of a standardized measure of wealth across time and at various levels of population aggregation in India. Indices were derived through principal components analysis (PCA) performed using standardized variables from a correlation matrix to minimize differences in variance. Valid and simple indices were constructed with the minimum number of assets needed to produce scores with enough variability to allow definition of unique decile cut-off points in each urban and rural area of all states. For all indices, the first PCA components explained between 36% and 43% of the variance in household assets. Using sub-national distributions of national wealth index scores, mean height-for-age z-scores increased from the poorest to the richest wealth quintiles for all surveys, and stunting prevalence was higher among the poorest and lower among the wealthiest. Urban and rural decile cut-off values for India, for the six regions and for the 24 major states revealed large variability in wealth by geographical area and level, and rural wealth score gaps exceeded those observed in urban areas. The large variability in sub-national distributions of national wealth index scores indicates the importance of accounting for such variation when constructing wealth indices and deriving score distribution cut-off points. Such an approach allows for proper within-sample economic classification, resulting in scores that are valid indicators of wealth and correlate well with health outcomes, and enables wealth-related analyses at

  13. National direct-drive program on OMEGA and the National Ignition Facility

    NASA Astrophysics Data System (ADS)

    Goncharov, V. N.; Regan, S. P.; Campbell, E. M.; Sangster, T. C.; Radha, P. B.; Myatt, J. F.; Froula, D. H.; Betti, R.; Boehly, T. R.; Delettrez, J. A.; Edgell, D. H.; Epstein, R.; Forrest, C. J.; Glebov, V. Yu; Harding, D. R.; Hu, S. X.; Igumenshchev, I. V.; Marshall, F. J.; McCrory, R. L.; Michel, D. T.; Seka, W.; Shvydky, A.; Stoeckl, C.; Theobald, W.; Gatu-Johnson, M.

    2017-01-01

    A major advantage of the laser direct-drive (DD) approach to ignition is the increased fraction of laser drive energy coupled to the hot spot and relaxed hot-spot requirements for the peak pressure and convergence ratios relative to the indirect-drive approach at equivalent laser energy. With the goal of a successful ignition demonstration using DD, the recently established national strategy has several elements and involves multiple national and international institutions. These elements include the experimental demonstration on OMEGA cryogenic implosions of hot-spot conditions relevant for ignition at MJ-scale energies available at the National Ignition Facility (NIF) and developing an understanding of laser-plasma interactions and laser coupling using DD experiments on the NIF. DD designs require reaching central stagnation pressures in excess of 100 Gbar. The current experiments on OMEGA have achieved inferred peak pressures of 56 Gbar (Regan et al 2016 Phys. Rev. Lett. 117 025001). Extensive analysis of the cryogenic target experiments and two- and three-dimensional simulations suggest that power balance, target offset, and target quality are the main limiting factors in target performance. In addition, cross-beam energy transfer (CBET) has been identified as the main mechanism reducing laser coupling. Reaching the goal of demonstrating hydrodynamic equivalence on OMEGA includes improving laser power balance, target position, and target quality at shot time. CBET must also be significantly reduced and several strategies have been identified to address this issue.

  14. Biosecurity in the age of Big Data: a conversation with the FBI.

    PubMed

    You, Edward; Kozminski, Keith G

    2015-11-05

    New scientific frontiers and emerging technologies within the life sciences pose many global challenges to society. Big Data is a premier example, especially with respect to individual, national, and international security. Here a Special Agent of the Federal Bureau of Investigation discusses the security implications of Big Data and the need for security in the life sciences. © 2015 Kozminski. This article is distributed by The American Society for Cell Biology under license from the author(s). Two months after publication it is available to the public under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License (http://creativecommons.org/licenses/by-nc-sa/3.0).

  15. Conquest or Reconquest? Students' Conceptions of Nation Embedded in a Historical Narrative

    ERIC Educational Resources Information Center

    Lopez, Cesar; Carretero, Mario; Rodriguez-Moneo, Maria

    2015-01-01

    This article focuses on university students' understanding of the concept of nation. First an analysis of this concept from a historiographical point of view is presented. This allows for distinguishing between different conceptions of the nation related to 3 main approaches: the romantic, the modernist, and the ethnosymbolic approaches. Based on…

  16. Remotely sensing the German Wadden Sea-a new approach to address national and international environmental legislation.

    PubMed

    Müller, Gabriele; Stelzer, Kerstin; Smollich, Susan; Gade, Martin; Adolph, Winny; Melchionna, Sabrina; Kemme, Linnea; Geißler, Jasmin; Millat, Gerald; Reimers, Hans-Christian; Kohlus, Jörn; Eskildsen, Kai

    2016-10-01

    The Wadden Sea along the North Sea coasts of Denmark, Germany, and the Netherlands is the largest unbroken system of intertidal sand and mud flats in the world. Its habitats are highly productive and harbour high standing stocks and densities of benthic species, well adapted to the demanding environmental conditions. Therefore, the Wadden Sea is one of the most important areas for migratory birds in the world and thus protected by national and international legislation, which amongst others requires extensive monitoring. Due to the inaccessibility of major areas of the Wadden Sea, a classification approach based on optical and radar remote sensing has been developed to support environmental monitoring programmes. In this study, the general classification framework as well as two specific monitoring cases, mussel beds and seagrass meadows, are presented. The classification of mussel beds profits highly from inclusion of radar data due to their rough surface and achieves agreements of up to 79 % with areal data from the regular monitoring programme. Classification of seagrass meadows reaches even higher agreements with monitoring data (up to 100 %) and furthermore captures seagrass densities as low as 10 %. The main classification results are information on area and location of individual habitats. These are needed to fulfil environmental legislation requirements. One of the major advantages of this approach is the large areal coverage with individual satellite images, allowing simultaneous assessment of both accessible and inaccessible areas and thus providing a more complete overall picture.

  17. A new phase-correlation-based iris matching for degraded images.

    PubMed

    Krichen, Emine; Garcia-Salicetti, Sonia; Dorizzi, Bernadette

    2009-08-01

    In this paper, we present a new phase-correlation-based iris matching approach in order to deal with degradations in iris images due to unconstrained acquisition procedures. Our matching system is a fusion of global and local Gabor phase-correlation schemes. The main originality of our local approach is that we do not only consider the correlation peak amplitudes but also their locations in different regions of the images. Results on several degraded databases, namely, the CASIA-BIOSECURE and Iris Challenge Evaluation 2005 databases, show the improvement of our method compared to two available reference systems, Masek and Open Source for Iris (OSRIS), in verification mode.

  18. Addressing the Misuse Potential of Life Science Research-Perspectives From a Bottom-Up Initiative in Switzerland.

    PubMed

    Oeschger, Franziska M; Jenal, Ursula

    2018-01-01

    Codes of conduct have received wide attention as a bottom-up approach to foster responsibility for dual use aspects of life science research within the scientific community. In Switzerland, a series of discussion sessions led by the Swiss Academy of Sciences with over 40 representatives of most Swiss academic life science research institutions has revealed that while a formal code of conduct was considered too restrictive, a bottom-up approach toward awareness raising and education and demonstrating scientists' responsibility toward society was highly welcomed. Consequently, an informational brochure on "Misuse potential and biosecurity in life sciences research" was developed to provide material for further discussions and education.

  19. Cross-national comparability of the WHOQOL-BREF: a measurement invariance approach.

    PubMed

    Theuns, Peter; Hofmans, Joeri; Mazaheri, Mehrdad; Van Acker, Frederik; Bernheim, Jan L

    2010-03-01

    To evaluate whether the WHOQOL-BREF measures the QOL construct in the same way across nations. Students from Flanders, Belgium and Iran completed the WHOQOL-BREF as part of a larger Quality of Life questionnaire. Their responses were compared using a multi-group confirmatory factor analysis. In general, the QOL construct appears rather similar in both cultures; however, participants from both countries seem to respond differently to particular items of the WHOQOL-BREF. Especially for the physical and psychological domain, this is problematic, because none of their indicators works in the same way across samples. Notwithstanding some limitations of this study, it must be concluded that the WHOQOL-BREF should only be used with great caution in cross-national comparisons. © Springer Science+Business Media B.V. 2010

  20. The Asian Human Resource Approach in Global Perspective.

    ERIC Educational Resources Information Center

    Cummings, William K.

    1995-01-01

    Challenges the prevailing Western approach to education by asserting that several Asian nations have and are developing a distinctive approach to human resource development. Describes characteristics of this approach and contrasts it to the Western model. (CFR)

  1. The National Children's Study: Recruitment Outcomes Using an Enhanced Household-Based Approach.

    PubMed

    Blaisdell, Laura L; Zellner, Jennifer A; King, Alison A; Faustman, Elaine; Wilhelm, Mari; Hudak, Mark L; Annett, Robert D

    2016-06-01

    Ten National Children's Study (NCS) study locations with diverse demographic characteristics used an enhanced household-based recruitment (EHBR) approach to enroll preconceptional and pregnant women. Study centers used different types and dosages of community outreach and engagement (COE) activities and supplemental strategies. The goal of the study was to determine whether variability in enumeration and recruitment outcomes correlated with study location characteristics or types and dosages of COE activities (number of COE events, number of advance household mailings, total media expenditures, and total COE expenditures). Each of the sites provided data on COE activities, protocol implementation, supplemental recruitment activities, location demographic characteristics, and enumeration/recruitment outcomes. COE activities varied across sites in breadth and scope. Numerous strategies were used, including media advertising, social media, participation in community-wide events, presentations to stakeholders, and creation of advisory boards. Some sites included supplemental recruitment efforts. EHBR sites enrolled 1404 women at the initial pregnancy screening. No significant relationships were found between study location demographic characteristics or between the types and dosages of COE activities and recruitment outcomes. Probability sampling for a long-term study requires a positive image with stakeholders and within communities; this requirement may be especially true for door-to-door recruitment. EHBR sites successfully recruited a representative sample of preconceptional and pregnant women. Sites reported implementing similar COE activities but with varying dosage and cost; however, analyses did not support a benefit of COE strategies on study recruitment. Copyright © 2016 by the American Academy of Pediatrics.

  2. Engineering H5N1 avian influenza viruses to study human adaptation

    PubMed Central

    Morens, David M.; Subbarao, Kanta; Taubenberger, Jeffery K.

    2013-01-01

    Two studies of H5N1 avian influenza viruses that had been genetically engineered to render them transmissible between ferrets have proved highly controversial. Divergent opinions exist about the importance of these studies of influenza transmission and about potential ‘dual use’ research implications. No consensus has developed yet about how to balance these concerns. After not recommending immediate full publication of earlier, less complete versions of the studies, the United States National Science Advisory Board for Biosecurity subsequently recommended full publication of more complete manuscripts; however, controversy about this and similar research remains. PMID:22722191

  3. The National Nanotechnology Initiative: Overview, Reauthorization, and Appropriations Issues

    DTIC Science & Technology

    2010-03-18

    and Health, July 2006. 91 Progress Toward Safe Nanotechnology in the Workplace , National Institute for Occupational Safety and Health, June 2007. 92...2007. Progress Toward Safe Nanotechnology in the Workplace , National Institute for Occupational Safety and Health. June 2007. Approaches to Safe...Nanotechnology in the Workplace , National Institute for Occupational Safety and Health. July 2006. Nanoscale Science, Engineering, and Technology in

  4. The National Nanotechnology Initiative: Overview, Reauthorization, and Appropriations Issues

    DTIC Science & Technology

    2010-05-13

    Health, July 2006. 91 Progress Toward Safe Nanotechnology in the Workplace , National Institute for Occupational Safety and Health, June 2007. 92 NIOSH...Toward Safe Nanotechnology in the Workplace , National Institute for Occupational Safety and Health. June 2007. Approaches to Safe Nanotechnology in...the Workplace , National Institute for Occupational Safety and Health. July 2006. Nanoscale Science, Engineering, and Technology in DOE’s Office of

  5. One Health approach to controlling a Q fever outbreak on an Australian goat farm.

    PubMed

    Bond, K A; Vincent, G; Wilks, C R; Franklin, L; Sutton, B; Stenos, J; Cowan, R; Lim, K; Athan, E; Harris, O; Macfarlane-Berry, L; Segal, Y; Firestone, S M

    2016-04-01

    A recent outbreak of Q fever was linked to an intensive goat and sheep dairy farm in Victoria, Australia, 2012-2014. Seventeen employees and one family member were confirmed with Q fever over a 28-month period, including two culture-positive cases. The outbreak investigation and management involved a One Health approach with representation from human, animal, environmental and public health. Seroprevalence in non-pregnant milking goats was 15% [95% confidence interval (CI) 7-27]; active infection was confirmed by positive quantitative PCR on several animal specimens. Genotyping of Coxiella burnetii DNA obtained from goat and human specimens was identical by two typing methods. A number of farming practices probably contributed to the outbreak, with similar precipitating factors to the Netherlands outbreak, 2007-2012. Compared to workers in a high-efficiency particulate arrestance (HEPA) filtered factory, administrative staff in an unfiltered adjoining office and those regularly handling goats and kids had 5·49 (95% CI 1·29-23·4) and 5·65 (95% CI 1·09-29·3) times the risk of infection, respectively; suggesting factory workers were protected from windborne spread of organisms. Reduction in the incidence of human cases was achieved through an intensive human vaccination programme plus environmental and biosecurity interventions. Subsequent non-occupational acquisition of Q fever in the spouse of an employee, indicates that infection remains endemic in the goat herd, and remains a challenge to manage without source control.

  6. Determination of the sources and antimicrobial resistance patterns of Salmonella isolated from the poultry industry in Southern Ethiopia.

    PubMed

    Abdi, Reta Duguma; Mengstie, Fisseha; Beyi, Ashenafi Feyisa; Beyene, Takele; Waktole, Hika; Mammo, Bedasso; Ayana, Dinka; Abunna, Fufa

    2017-05-18

    Ethiopia set an ambitious masterplan to increase chicken meat and egg production from 2015 to 2020. Poultry breeding, multiplication and distribution centers in the country have received executive order to import, amplify and distribute commercial chickens to end users. The biosecurity and the pathogen fauna of the centers have not been evaluated as to whether the centers could implement the mission effectively without any risk. Thus, the aim of this study was to evaluate the biosecurity practices and the pathogen prevalence, risk factors and their antimicrobial resistance (AMR) using Salmonella as case study. Routine farm workers of the centers were interviewed about the different management (biosecurity) practices using a checklist. Samples (n = 270) from different sources consisting of chicken's cloacal swab (n = 244), personnel hand swab (n = 9) and bedding (n = 17) were collected from three chicken multiplication centers. Standard bacteriological methods were used for the isolation of Salmonella. Disk diffusion method was used for drug sensitivity testing. Antimicrobials were often over prescribed without confirming the cause of ill health and without susceptibility testing. The general biosecurity and flock management practices were substandard. Salmonella was isolated from 45 (16.7%) of the 270 samples. Its prevalence was significantly (p<0.05) associated with location of the multiplication center, 27% at Bonga and 10.6% at Hawassa. Sample type was also significantly (p<0.05) affected in that it was higher in the bedding (35.3%) and personnel hand swabs (33.3%) than in the chicken cloaca (14.8%), which demonstrates the poor biosecurity and personnel hygienic practices in the centers. All of the 45 isolates (100%) exhibited resistance to kanamycin and sulfamethoxazole-trimethoprim, nalidixic acid (97.8%), ampicillin (97.8%), cefoxitin (97.8%), streptomycin (97.8%) tetracycline (97.8%), chloramphenicol (91.3%), ciprofloxacin (31.1%), and gentamicin (0

  7. A new approach to mentoring for research careers: the National Research Mentoring Network.

    PubMed

    Sorkness, Christine A; Pfund, Christine; Ofili, Elizabeth O; Okuyemi, Kolawole S; Vishwanatha, Jamboor K; Zavala, Maria Elena; Pesavento, Theresa; Fernandez, Mary; Tissera, Anthony; Deveci, Alp; Javier, Damaris; Short, Alexis; Cooper, Paige; Jones, Harlan; Manson, Spero; Buchwald, Dedra; Eide, Kristin; Gouldy, Andrea; Kelly, Erin; Langford, Nicole; McGee, Richard; Steer, Clifford; Unold, Thad; Weber-Main, Anne Marie; Báez, Adriana; Stiles, Jonathan; Pemu, Priscilla; Thompson, Winston; Gwathmey, Judith; Lawson, Kimberly; Johnson, Japera; Hall, Meldra; Paulsen, Douglas; Fouad, Mona; Smith, Ann; Luna, Rafael; Wilson, Donald; Adelsberger, Greg; Simenson, Drew; Cook, Abby; Feliu-Mojer, Monica; Harwood, Eileen; Jones, Amy; Branchaw, Janet; Thomas, Stephen; Butz, Amanda; Byars-Winston, Angela; House, Stephanie; McDaniels, Melissa; Quinn, Sandra; Rogers, Jenna; Spencer, Kim; Utzerath, Emily; Duplicate Of Weber-Main; Womack, Veronica

    2017-01-01

    Effective mentorship is critical to the success of early stage investigators, and has been linked to enhanced mentee productivity, self-efficacy, and career satisfaction. The mission of the National Research Mentoring Network (NRMN) is to provide all trainees across the biomedical, behavioral, clinical, and social sciences with evidence-based mentorship and professional development programming that emphasizes the benefits and challenges of diversity, inclusivity, and culture within mentoring relationships, and more broadly the research workforce. The purpose of this paper is to describe the structure and activities of NRMN. NRMN serves as a national training hub for mentors and mentees striving to improve their relationships by better aligning expectations, promoting professional development, maintaining effective communication, addressing equity and inclusion, assessing understanding, fostering independence, and cultivating ethical behavior. Training is offered in-person at institutions, regional training, or national meetings, as well as via synchronous and asynchronous platforms; the growing training demand is being met by a cadre of NRMN Master Facilitators. NRMN offers career stage-focused coaching models for grant writing, and other professional development programs. NRMN partners with diverse stakeholders from the NIH-sponsored Diversity Program Consortium (DPC), as well as organizations outside the DPC to work synergistically towards common diversity goals. NRMN offers a virtual portal to the Network and all NRMN program offerings for mentees and mentors across career development stages. NRMNet provides access to a wide array of mentoring experiences and resources including MyNRMN, Guided Virtual Mentorship Program, news, training calendar, videos, and workshops. National scale and sustainability are being addressed by NRMN "Coaches-in-Training" offerings for more senior researchers to implement coaching models across the nation. "Shark Tanks" provide

  8. Attributes of innovations and approaches to scalability - lessons from a national program to extend the scope of practice of health professionals.

    PubMed

    Masso, Malcolm; Thompson, Cristina

    2016-01-01

    The context for the paper was the evaluation of a national program in Australia to investigate extended scopes of practice for health professionals (paramedics, physiotherapists, and nurses). The design of the evaluation involved a mixed-methods approach with multiple data sources. Four multidisciplinary models of extended scope of practice were tested over an 18-month period, involving 26 organizations, 224 health professionals, and 36 implementation sites. The evaluation focused on what could be learned to inform scaling up the extended scopes of practice on a national scale. The evaluation findings were used to develop a conceptual framework for use by clinicians, managers, and policy makers to determine appropriate strategies for scaling up effective innovations. Development of the framework was informed by the literature on the diffusion of innovations, particularly an understanding that certain attributes of innovations influence adoption. The framework recognizes the role played by three groups of stakeholders: evidence producers, evidence influencers, and evidence adopters. The use of the framework is illustrated with four case studies from the evaluation. The findings demonstrate how the scaling up of innovations can be influenced by three quite distinct approaches - letting adoption take place in an uncontrolled, unplanned, way; actively helping the process of adoption; or taking deliberate steps to ensure that adoption takes place. Development of the conceptual framework resulted in two sets of questions to guide decisions about scalability, one for those considering whether to adopt the innovation (evidence adopters), and the other for those trying to decide on the optimal strategy for dissemination (evidence influencers).

  9. Understanding National Models for Climate Assessments

    NASA Astrophysics Data System (ADS)

    Dave, A.; Weingartner, K.

    2017-12-01

    National-level climate assessments have been produced or are underway in a number of countries. These efforts showcase a variety of approaches to mapping climate impacts onto human and natural systems, and involve a variety of development processes, organizational structures, and intended purposes. This presentation will provide a comparative overview of national `models' for climate assessments worldwide, drawing from a geographically diverse group of nations with varying capacities to conduct such assessments. Using an illustrative sampling of assessment models, the presentation will highlight the range of assessment mandates and requirements that drive this work, methodologies employed, focal areas, and the degree to which international dimensions are included for each nation's assessment. This not only allows the U.S. National Climate Assessment to be better understood within an international context, but provides the user with an entry point into other national climate assessments around the world, enabling a better understanding of the risks and vulnerabilities societies face.

  10. Current approaches to norms research

    Treesearch

    John L. Heywood

    2000-01-01

    The dialogue session was a continuation of a debate about norms and the application of normative standards to wilderness management that has taken place throughout the 1990s at national meetings and in the research literature. Researchers who have made significant contributions to the normative approach to wilderness recreation management presented three approaches to...

  11. Evaluating the sub-national fidelity of national Initiatives in decentralized health systems: Integrated Primary Health Care Governance in Nigeria.

    PubMed

    Eboreime, Ejemai Amaize; Abimbola, Seye; Obi, Felix Abrahams; Ebirim, Obinna; Olubajo, Olalekan; Eyles, John; Nxumalo, Nonhlanhla Lynette; Mambulu, Faith Nankasa

    2017-03-21

    Policy making, translation and implementation in politically and administratively decentralized systems can be challenging. Beyond the mere sub-national acceptance of national initiatives, adherence to policy implementation processes is often poor, particularly in low and middle-income countries. In this study, we explore the implementation fidelity of integrated PHC governance policy in Nigeria's decentralized governance system and its implications on closing implementation gaps with respect to other top-down health policies and initiatives. Having engaged policy makers, we identified 9 core components of the policy (Governance, Legislation, Minimum Service Package, Repositioning, Systems Development, Operational Guidelines, Human Resources, Funding Structure, and Office Establishment). We evaluated the level and pattern of implementation at state level as compared to the national guidelines using a scorecard approach. Contrary to national government's assessment of level of compliance, we found that sub-national governments exercised significant discretion with respect to the implementation of core components of the policy. Whereas 35 and 32% of states fully met national criteria for the structural domains of "Office Establishment" and Legislation" respectively, no state was fully compliant to "Human Resource Management" and "Funding" requirements, which are more indicative of functionality. The pattern of implementation suggests that, rather than implementing to improve outcomes, state governments may be more interested in executing low hanging fruits in order to access national incentives. Our study highlights the importance of evaluating implementation fidelity in providing evidence of implementation gaps towards improving policy execution, particularly in decentralized health systems. This approach will help national policy makers identify more effective ways of supporting lower tiers of governance towards improvement of health systems and outcomes.

  12. An introduction to the indirect exposure assessment approach: modeling human exposure using microenvironmental measurements and the recent National Human Activity Pattern Survey.

    PubMed Central

    Klepeis, N E

    1999-01-01

    Indirect exposure approaches offer a feasible and accurate method for estimating population exposures to indoor pollutants, including environmental tobacco smoke (ETS). In an effort to make the indirect exposure assessment approach more accessible to people in the health and risk assessment fields, this paper provides examples using real data from (italic>a(/italic>) a week-long personal carbon monoxide monitoring survey conducted by the author; and (italic>b(/italic>) the 1992 to 1994 National Human Activity Pattern Survey (NHAPS) for the United States. The indirect approach uses measurements of exposures in specific microenvironments (e.g., homes, bars, offices), validated microenvironmental models (based on the mass balance equation), and human activity pattern data obtained from questionnaires to predict frequency distributions of exposure for entire populations. This approach requires fewer resources than the direct approach to exposure assessment, for which the distribution of monitors to a representative sample of a given population is necessary. In the indirect exposure assessment approach, average microenvironmental concentrations are multiplied by the total time spent in each microenvironment to give total integrated exposure. By assuming that the concentrations encountered in each of 10 location categories are the same for different members of the U.S. population (i.e., the NHAPS respondents), the hypothetical contribution that ETS makes to the average 24-hr respirable suspended particle exposure for Americans working their main job is calculated in this paper to be 18 microg/m3. This article is an illustrative review and does not contain an actual exposure assessment or model validation. Images Figure 3 Figure 4 PMID:10350522

  13. National hydrogen technology competitiveness analysis with an integrated fuzzy AHP and TOPSIS approaches: In case of hydrogen production and storage technologies

    NASA Astrophysics Data System (ADS)

    Lee, Seongkon; Mogi, Gento

    2017-02-01

    The demand of fossil fuels, including oil, gas, and coal has been increasing with the rapid development of developing countries such as China and India. U.S., Japan, EU, and Korea have been making efforts to transfer to low carbon and green growth economics for sustainable development. And they also have been measuring to cope with climate change and the depletion of conventional fuels. Advanced nations implemented strategic energy technology development plans to lead the future energy market. Strategic energy technology development is crucial alternative to address the energy issues. This paper analyze the relative competitiveness of hydrogen energy technologies in case of hydrogen production and storage technologies from 2006 to 2010. Hydrogen energy technology is environmentally clean technology comparing with the previous conventional energy technologies and will play a key role to solve the greenhouse gas effect. Leading nations have increasingly focused on hydrogen technology R&D. This research is carried out the relative competitiveness of hydrogen energy technologies employed by an integrated fuzzy analytic hierarchy process (Fuzzy AHP) and The Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS) approaches. We make four criteria, accounting for technological status, R&D budget, R&D human resource, and hydrogen infra. This research can be used as fundamental data for implementing national hydrogen energy R&D planning for energy policy-makers.

  14. Alternatives to the use of antimicrobial agents in pig production: A multi-country expert-ranking of perceived effectiveness, feasibility and return on investment.

    PubMed

    Postma, Merel; Stärk, Katharina D C; Sjölund, Marie; Backhans, Annette; Beilage, Elisabeth Grosse; Lösken, Svenja; Belloc, Catherine; Collineau, Lucie; Iten, Denise; Visschers, Vivianne; Nielsen, Elisabeth O; Dewulf, Jeroen

    2015-03-01

    Nineteen alternatives to antimicrobial agents were ranked on perceived effectiveness, feasibility and return on investment (ROI) from 0 (not effective, not feasible, no ROI) to 10 (fully effective, completely feasible, maximum ROI) by 111 pig health experts from Belgium, Denmark, France, Germany, Sweden and Switzerland. The top 5 measures in terms of perceived effectiveness were (1) improved internal biosecurity, (2) improved external biosecurity, (3) improved climate/environmental conditions, (4) high health/Specific Pathogen Free/disease eradication and (5) increased vaccination. The top 5 measures in terms of perceived feasibility were (1) increased vaccination, (2) increased use of anti-inflammatory products, (3) improved water quality, (4) feed quality/optimization and (5) use of zinc/metals. The top 5 measures in terms of perceived ROI were (1) improved internal biosecurity, (2) zinc/metals, (3) diagnostics/action plan, (4) feed quality/optimization and (5) climate/environmental improvements. Univariate linear regression showed that veterinary practitioners rank internal biosecurity, vaccination, use of zinc/metals, feed quality optimization and climate/environmental on average highest, while researchers and professors focused more on increased use of diagnostics and action plans. Financial incentives/penalties ranked low in all countries. Belgian respondents ranked feed quality significantly lower compared to the German respondents while reduction of stocking density was ranked higher in Belgium compared to Denmark. Categorical Principal Component Analysis applied to the average ranking supported the finding that veterinary practitioners had a preference for more practical, common and already known alternatives. The results showed that improvements in biosecurity, increased use of vaccination, use of zinc/metals, feed quality improvement and regular diagnostic testing combined with a clear action plan were perceived to be the most promising alternatives to

  15. A case-control study of risk factors for equine influenza spread onto horse premises during the 2007 epidemic in Australia.

    PubMed

    Firestone, Simon M; Schemann, Kathrin A; Toribio, Jenny-Ann L M L; Ward, Michael P; Dhand, Navneet K

    2011-06-01

    The 2007 epidemic of equine influenza in Australia provided an opportunity to investigate the effectiveness of on-farm biosecurity measures in preventing the spread of a novel pathogen in a largely naive population. We conducted a case-control study of 200 horse premises from highly affected regions of the state of New South Wales (NSW), to investigate risk factors for the spread of equine influenza onto horse premises, specifically, non-compliance with biosecurity measures recommended to horse owners by the relevant animal health authority, the NSW Department of Primary Industries. The study was restricted to cases occurring during the first seven weeks of the epidemic, a period prior to vaccination and the relaxation of some movement restrictions. Case and control premises were selected from a laboratory testing dataset and interviews were conducted with horse owners and managers on premises between July and November 2009. The proximity of premises to the nearest infected premises was the factor most strongly associated with case status. Case premises were more likely than control premises to be within 5 km and beyond 10 km of an infected premises. Having a footbath in place on the premises before any horses were infected was associated with a nearly four-fold reduction in odds of infection (odds ratio=0.27; 95% confidence interval: 0.09, 0.83). This protective association may have reflected overall premises biosecurity standards related to the fomite transmission of equine influenza. Compliance with certain on-farm biosecurity practices seemingly prevented horses on premises in high risk areas being infected with equine influenza during the 2007 outbreak in Australia. In future outbreaks, in addition to broader disease control measures, on-farm biosecurity practices should be adopted by horse owners and managers to prevent equine influenza spread. Copyright © 2011 Elsevier B.V. All rights reserved.

  16. The national e-medication approaches in Germany, Switzerland and Austria: A structured comparison.

    PubMed

    Gall, Walter; Aly, Amin-Farid; Sojer, Reinhold; Spahni, Stéphane; Ammenwerth, Elske

    2016-09-01

    Recent studies show that many patients are harmed due to missing or erroneous information on prescribed and taken medication. Many countries are thus introducing eHealth solutions to improve the availability of this medication information on a national scale (often called "e-medication"). The objective of this study is to analyse and compare the national e-medication solutions just being introduced in Germany, Switzerland and Austria. Information on the situation in the three countries was collected within an expert group and complemented by an analysis of recent literature and legislation in each country. All three countries formulate comparable goals for the national eHealth solutions, focusing on improving medication safety. All three countries do not have a national e-prescription system. In all three countries, the implementation process was slower than expected and e-medication is not yet fully available. Differences of the three countries exist regarding chosen architectures, used standards, offered functionalities, and degree of voluntariness of participation. Nationwide e-medication systems and cross-border harmonization are acknowledged as important goals towards medication safety, but they develop slowly mainly due to privacy and security requirements, the need for law amendments and last but not least political interests. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  17. Technological Strategies and National Purpose

    ERIC Educational Resources Information Center

    Gilpin, Robert

    1970-01-01

    Discusses the international and domestic implications of technological growth. Defines three basic national strategies: a broad front approach, scientific and technological specialization and importation. Analyzes the strategies followed by form countries - France, the United States, Sweden, and Japan- to illustrate the alternatives and the…

  18. Australian Recognition Framework Arrangements. Australia's National Training Framework.

    ERIC Educational Resources Information Center

    Australian National Training Authority, Brisbane.

    This document explains the objectives, principles, standards, and protocols of the Australian Recognition Framework (ARF), which is a comprehensive approach to national recognition of vocational education and training (VET) that is based on a quality-assured approach to the registration of training organizations seeking to deliver training, assess…

  19. Local Distributions of Wealth to Describe Health Inequalities in India: A New Approach for Analyzing Nationally Representative Household Survey Data, 1992–2008

    PubMed Central

    Bassani, Diego G.; Corsi, Daniel J.; Gaffey, Michelle F.; Barros, Aluisio J. D.

    2014-01-01

    Background Worse health outcomes including higher morbidity and mortality are most often observed among the poorest fractions of a population. In this paper we present and validate national, regional and state-level distributions of national wealth index scores, for urban and rural populations, derived from household asset data collected in six survey rounds in India between 1992–3 and 2007–8. These new indices and their sub-national distributions allow for comparative analyses of a standardized measure of wealth across time and at various levels of population aggregation in India. Methods Indices were derived through principal components analysis (PCA) performed using standardized variables from a correlation matrix to minimize differences in variance. Valid and simple indices were constructed with the minimum number of assets needed to produce scores with enough variability to allow definition of unique decile cut-off points in each urban and rural area of all states. Results For all indices, the first PCA components explained between 36% and 43% of the variance in household assets. Using sub-national distributions of national wealth index scores, mean height-for-age z-scores increased from the poorest to the richest wealth quintiles for all surveys, and stunting prevalence was higher among the poorest and lower among the wealthiest. Urban and rural decile cut-off values for India, for the six regions and for the 24 major states revealed large variability in wealth by geographical area and level, and rural wealth score gaps exceeded those observed in urban areas. Conclusions The large variability in sub-national distributions of national wealth index scores indicates the importance of accounting for such variation when constructing wealth indices and deriving score distribution cut-off points. Such an approach allows for proper within-sample economic classification, resulting in scores that are valid indicators of wealth and correlate well with health

  20. Species distribution models: A comparison of statistical approaches for livestock and disease epidemics.

    PubMed

    Hollings, Tracey; Robinson, Andrew; van Andel, Mary; Jewell, Chris; Burgman, Mark

    2017-01-01

    In livestock industries, reliable up-to-date spatial distribution and abundance records for animals and farms are critical for governments to manage and respond to risks. Yet few, if any, countries can afford to maintain comprehensive, up-to-date agricultural census data. Statistical modelling can be used as a proxy for such data but comparative modelling studies have rarely been undertaken for livestock populations. Widespread species, including livestock, can be difficult to model effectively due to complex spatial distributions that do not respond predictably to environmental gradients. We assessed three machine learning species distribution models (SDM) for their capacity to estimate national-level farm animal population numbers within property boundaries: boosted regression trees (BRT), random forests (RF) and K-nearest neighbour (K-NN). The models were built from a commercial livestock database and environmental and socio-economic predictor data for New Zealand. We used two spatial data stratifications to test (i) support for decision making in an emergency response situation, and (ii) the ability for the models to predict to new geographic regions. The performance of the three model types varied substantially, but the best performing models showed very high accuracy. BRTs had the best performance overall, but RF performed equally well or better in many simulations; RFs were superior at predicting livestock numbers for all but very large commercial farms. K-NN performed poorly relative to both RF and BRT in all simulations. The predictions of both multi species and single species models for farms and within hypothetical quarantine zones were very close to observed data. These models are generally applicable for livestock estimation with broad applications in disease risk modelling, biosecurity, policy and planning.

  1. Species distribution models: A comparison of statistical approaches for livestock and disease epidemics

    PubMed Central

    Robinson, Andrew; van Andel, Mary; Jewell, Chris; Burgman, Mark

    2017-01-01

    In livestock industries, reliable up-to-date spatial distribution and abundance records for animals and farms are critical for governments to manage and respond to risks. Yet few, if any, countries can afford to maintain comprehensive, up-to-date agricultural census data. Statistical modelling can be used as a proxy for such data but comparative modelling studies have rarely been undertaken for livestock populations. Widespread species, including livestock, can be difficult to model effectively due to complex spatial distributions that do not respond predictably to environmental gradients. We assessed three machine learning species distribution models (SDM) for their capacity to estimate national-level farm animal population numbers within property boundaries: boosted regression trees (BRT), random forests (RF) and K-nearest neighbour (K-NN). The models were built from a commercial livestock database and environmental and socio-economic predictor data for New Zealand. We used two spatial data stratifications to test (i) support for decision making in an emergency response situation, and (ii) the ability for the models to predict to new geographic regions. The performance of the three model types varied substantially, but the best performing models showed very high accuracy. BRTs had the best performance overall, but RF performed equally well or better in many simulations; RFs were superior at predicting livestock numbers for all but very large commercial farms. K-NN performed poorly relative to both RF and BRT in all simulations. The predictions of both multi species and single species models for farms and within hypothetical quarantine zones were very close to observed data. These models are generally applicable for livestock estimation with broad applications in disease risk modelling, biosecurity, policy and planning. PMID:28837685

  2. Non-US approaches to space commercialization

    NASA Technical Reports Server (NTRS)

    Smith, P. G.

    1984-01-01

    The approaches to the commercialization of space taken by the four foreign countries most active in the field - Canada, France, the Federal Republic of Germany, and Japan are described. National space program elements with commercial potential are examined in the context of national industrial and science policies, with special attention to objectives, timetables, and budgetary priority relative to other sectors. The role of the European Space Agency in attaining national and regional commercialization objectives is also examined.

  3. Building National Capacity for Research Mentor Training: An Evidence-Based Approach to Training the Trainers

    PubMed Central

    Pfund, Christine; Spencer, Kimberly C.; Asquith, Pamela; House, Stephanie C.; Miller, Sarah; Sorkness, Christine A.

    2015-01-01

    Research mentor training (RMT), based on the published Entering Mentoring curricula series, has been shown to improve the knowledge and skills of research mentors across career stages, as self-reported by both the mentors engaged in training and their mentees. To promote widespread dissemination and empower others to implement this evidence-based training at their home institutions, we developed an extensive, interactive, multifaceted train-the-trainer workshop. The specific goals of these workshops are to 1) increase facilitator knowledge of an RMT curriculum, 2) increase facilitator confidence in implementing the curriculum, 3) provide a safe environment to practice facilitation of curricular activities, and 4) review implementation strategies and evaluation tools. Data indicate that our approach results in high satisfaction and significant confidence gains among attendees. Of the 195 diverse attendees trained in our workshops since Fall 2010, 44% report implementation at 39 different institutions, collectively training more than 500 mentors. Further, mentors who participated in the RMT sessions led by our trained facilitators report high facilitator effectiveness in guiding discussion. Implications and challenges to building the national capacity needed for improved research mentoring relationships are discussed. PMID:26033872

  4. Plants genetic manipulation: an approach from intellectual property.

    PubMed

    Ruiz, Anisley Negrin; Rivero, Lazaro Pino

    2013-01-01

    From the end of the 20th century the Biotechnology has experimented a vertiginous advance so far, putting on approval concepts like bio-security and bioethics; becoming this way, the work with the genome of the plants, in a matter is worthy to be reconsidered by the juridical mark that regulates it, in order to moderate the norm to the new scientific context. The Intellectual Property, when recognizing patent rights on products that have incorporate biological material, as well as to the obtainer about the new vegetable varieties obtained, could mean an obstacle that impedes or hinder the access from the society to that product or that variety. In the same way is worthy of consideration, the fact that such products or varieties can be a risk for the human health or the Environment, and a monopoly of commercial exploitation for the holder of the patent or of the obtainer certificate. This study is about this topic; and valuation about aspects of Biotechnology related with the genome of the plants and their juridical protection, in the international sand as well in Cuba.

  5. A Gentle Approach for Young Infants.

    ERIC Educational Resources Information Center

    Suskind, Diana; Kozma, Marta

    The Gentle Approach is a method for lifting infants younger than 6 months that promotes security and reassurance during adult-imposed changes in position. Developed at the Emmi Pilker National Methodological Institute for Residential Nurseries in Budapest, Hungary, the approach provides continual support and less opportunity for unprotected…

  6. Indicators of standards of the quality of the visitor experience at a heavily-used national park

    Treesearch

    Robert E. Manning; David W. Lime; Richard F. McMonagle

    1995-01-01

    Contemporary approaches to determining and managing carrying capacity of national parks and similar areas focus on indicators and standards of quality. The National Park Service is currently developing the Visitor Experience and Resource Protection process which adopts this approach to carrying capacity. This process is being applied to Arches National Park, Utah,...

  7. National Perspectives on Data Protection.

    ERIC Educational Resources Information Center

    Yurow, Jane

    1983-01-01

    Discussion of different approaches to protecting personal information in Europe and the United States highlights data protection laws and agreements (international transfer of personal data, European laws, United States state and federal laws), United States and European views of privacy protection, national economic and political goals, and…

  8. NATIONAL ELECTRONIC DISEASE SURVEILLANCE SYSTEM (NEDSS)

    EPA Science Inventory

    The National Electronic Disease Surveillance System (NEDSS) project is a public health initiative to provide a standard-based, integrated approach to disease surveillance and to connect public health surveillance to the burgeoning clinical information systems infrastructure. NEDS...

  9. Toward a national fuels mapping strategy: Lessons from selected mapping programs

    USGS Publications Warehouse

    Loveland, Thomas R.

    2001-01-01

    The establishment of a robust national fuels mapping program must be based on pertinent lessons from relevant national mapping programs. Many large-area mapping programs are under way in numerous Federal agencies. Each of these programs follows unique strategies to achieve mapping goals and objectives. Implementation approaches range from highly centralized programs that use tightly integrated standards and dedicated staff, to dispersed programs that permit considerable flexibility. One model facilitates national consistency, while the other allows accommodation of locally relevant conditions and issues. An examination of the programmatic strategies of four national vegetation and land cover mapping initiatives can identify the unique approaches, accomplishments, and lessons of each that should be considered in the design of a national fuel mapping program. The first three programs are the U.S. Geological Survey Gap Analysis Program, the U.S. Geological Survey National Land Cover Characterization Program, and the U.S. Fish and Wildlife Survey National Wetlands Inventory. A fourth program, the interagency Multiresolution Land Characterization Program, offers insights in the use of partnerships to accomplish mapping goals. Collectively, the programs provide lessons, guiding principles, and other basic concepts that can be used to design a successful national fuels mapping initiative.

  10. The 3D Elevation Program national indexing scheme

    USGS Publications Warehouse

    Thatcher, Cindy A.; Heidemann, Hans Karl; Stoker, Jason M.; Eldridge, Diane F.

    2017-11-02

    The 3D Elevation Program (3DEP) of the U.S. Geological Survey (USGS) acquires high-resolution elevation data for the Nation. This program has been operating under an opportunity-oriented approach, acquiring light detection and ranging (lidar) projects of varying sizes scattered across the United States. As a result, the national 3DEP elevation layer is subject to data gaps or unnecessary overlap between adjacent collections. To mitigate this problem, 3DEP is adopting a strategic, systematic approach to national data acquisition that will create efficiencies in efforts to achieve nationwide elevation data coverage and help capture additional Federal and non-Federal investments resulting from advance awareness of proposed acquisitions and partnership opportunities. The 3DEP Working Group, an interagency group managed by the USGS, has agreed that all future 3DEP collections within the lower 48 States should be coordinated by using a 1-kilometer by 1-kilometer tiling scheme for the conterminous United States. Fiscal Year 2018 is being considered a transition year, and in Fiscal Year 2019 the national indexing scheme will be fully implemented, so that all 3DEP-supported projects will be acquired and delivered in the national indexing scheme and projected into the Albers Equal Area projection. 

  11. Vocational Counselling and First Nations.

    ERIC Educational Resources Information Center

    Darou, Wes G.

    Some First Nations communities in northern Ontario have requested vocational counseling services to help youth select careers and reduce student attrition. However, Euro-American counseling practices may not be appropriate for Native clients. This paper describes the approach of the Anishanabek Educational Institute (AEI), which was established to…

  12. National survey of Australian paediatricians' approach to infant crying.

    PubMed

    Rimer, Romi; Hiscock, Harriet

    2014-03-01

    Persistent crying in infancy (i.e. crying that lasts for more than 3 h a day for more than 3 days per week for at least 3 weeks) is widespread. Although there is no gold standard approach to its management, guidelines exist with common management principles. This study aims to document how Australian general paediatricians (i) assess and manage persistent crying compared with published guidelines; (ii) screen for and manage associated post-natal depression; and (iii) rate their training in this area. Online survey were administered to all 394 members of the Australian Paediatric Research Network in November 2011 to February 2012. Members are predominantly general paediatricians. A total of 168 paediatricians (45%) responded. The majority (n = 96 (69%)) take one session to assess infant crying and at least two sessions to manage it (n = 106 (79%)). Specific approaches are not always evidence based (e.g. use of antacids/simethicone by 8%) and do not follow available guidelines. Most paediatricians routinely asked about maternal (n = 120 (88%)) but not paternal (n = 51 (33%)) mental health. Paediatricians typically received training around this issue before rather than after gaining formal paediatric qualifications (61% vs. 37%, respectively) and rate their training as satisfactory (67%). Despite this, only 39% feel very confident in managing infant crying. The lack of a gold standard approach to managing persistent infant crying has likely contributed to a lack of uniform care among Australian general paediatricians. Given that most paediatricians do not feel very confident in dealing with this problem, there is a scope for further training supported by evidence-based guidelines. © 2013 The Authors. Journal of Paediatrics and Child Health © 2013 Paediatrics and Child Health Division (Royal Australasian College of Physicians).

  13. Turning the tide: national policy approaches to increasing physical activity in seven European countries.

    PubMed

    Bull, Fiona; Milton, Karen; Kahlmeier, Sonja; Arlotti, Alberto; Juričan, Andrea Backović; Belander, Olov; Martin, Brian; Martin-Diener, Eva; Marques, Ana; Mota, Jorge; Vasankari, Tommi; Vlasveld, Anita

    2015-06-01

    Physical inactivity is one of the four leading behavioural risk factors for non-communicable disease (NCD). Like tobacco control, increasing levels of health-enhancing physical activity (HEPA) will require a national policy framework providing direction and a clear set of actions. Despite frequent calls, there has been insufficient progress on policy development in the majority of countries around the world. This study sought and summarised national HEPA policy in seven European countries (Finland, Italy, the Netherlands, Norway, Portugal, Slovenia and Switzerland). Data collection used a policy audit tool (PAT), a 27-item instrument structured into four sections. All countries reported some legislation or policy across the sectors of education, sport and health. Only some countries reported supportive policy in the transport and environment sectors. Five countries reported a stand-alone HEPA policy and six countries reported national recommendations. HEPA prevalence targets varied in magnitude and specificity and the presence of other relevant goals from different sectors highlighted the opportunity for joint action. Evaluation and the use of scientific evidence were endorsed but described as weak in practice. Only two countries reported a national multisector coordinating committee and most countries reported challenges with partnerships on different levels of policy implementation. Bringing together the key components for success within a national HEPA policy framework is not simple. This in-depth policy audit and country comparison highlighted similarities and differences and revealed new opportunities for consideration by other countries. These examples can inform countries within and beyond Europe and guide the development of national HEPA policy within the NCD prevention agenda. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  14. Mythscapes: memory, mythology, and national identity.

    PubMed

    Bell, Duncan

    2003-03-01

    In this paper I seek to challenge the dominant modes of conceiving the relationship between memory and national identity, and in so doing offer analysts of nationalism an improved understanding of the dynamics of national identity formation. The concept of collective memory is invoked regularly in attempts to explain the pervasiveness and power of nationalism. I argue that the concept is misused routinely in this context, and instead I employ a 'social agency' approach to theorizing, whereby memory is conceived in a more limited and cogent manner. I argue that it is important to distinguish clearly between memory and mythology, both of which are essential to understanding national identity, for not only are the two concepts distinct, they can also act in opposition to each other. Following from this I introduce the notion of a 'mythscape', the temporally and spatially extended discursive realm in which the myths of the nation are forged, transmitted, negotiated, and reconstructed constantly. Through employing the idea of a mythscape we can relate memory and mythology to each other in a theoretically profitable way.

  15. Attributes of innovations and approaches to scalability – lessons from a national program to extend the scope of practice of health professionals

    PubMed Central

    Masso, Malcolm; Thompson, Cristina

    2016-01-01

    The context for the paper was the evaluation of a national program in Australia to investigate extended scopes of practice for health professionals (paramedics, physiotherapists, and nurses). The design of the evaluation involved a mixed-methods approach with multiple data sources. Four multidisciplinary models of extended scope of practice were tested over an 18-month period, involving 26 organizations, 224 health professionals, and 36 implementation sites. The evaluation focused on what could be learned to inform scaling up the extended scopes of practice on a national scale. The evaluation findings were used to develop a conceptual framework for use by clinicians, managers, and policy makers to determine appropriate strategies for scaling up effective innovations. Development of the framework was informed by the literature on the diffusion of innovations, particularly an understanding that certain attributes of innovations influence adoption. The framework recognizes the role played by three groups of stakeholders: evidence producers, evidence influencers, and evidence adopters. The use of the framework is illustrated with four case studies from the evaluation. The findings demonstrate how the scaling up of innovations can be influenced by three quite distinct approaches – letting adoption take place in an uncontrolled, unplanned, way; actively helping the process of adoption; or taking deliberate steps to ensure that adoption takes place. Development of the conceptual framework resulted in two sets of questions to guide decisions about scalability, one for those considering whether to adopt the innovation (evidence adopters), and the other for those trying to decide on the optimal strategy for dissemination (evidence influencers). PMID:27616889

  16. An optimization approach to selecting research natural areas in National Forests

    Treesearch

    Stephanie A. Snyder; Lucy E. Tyrrell; Robert G. Haight

    1999-01-01

    The USDA Forest Service has a long-established program to identify areas in national forests for designation as protected Research Natural Areas (RNAs). One of the goals is to protect high quality examples of regional ecosystems for the purposes of maintaining biological diversity, conducting nonmanipulative research and monitoring, and fostering education. When RNA...

  17. National Institute of Neurological Disorders and Stroke Common Data Element Project - approach and methods.

    PubMed

    Grinnon, Stacie T; Miller, Kristy; Marler, John R; Lu, Yun; Stout, Alexandra; Odenkirchen, Joanne; Kunitz, Selma

    2012-06-01

    In neuroscience clinical research studies, much time and effort are devoted to deciding what data to collect and developing data collection forms and data management systems to capture the data. Many investigators receiving funding from National Institute of Neurological Disorders and Stroke (NINDS), the National Institutes of Health (NIH), are required to share their data once their studies are complete, but the multitude of data definitions and formats make it extremely difficult to aggregate data or perform meta-analyses across studies. In an effort to assist investigators and accelerate data sharing in neuroscience clinical research, the NINDS has embarked upon the Common Data Element (CDE) Project. The data standards developed through the NINDS CDE Project enable clinical investigators to systematically collect data and should facilitate study start-up and data aggregation across the research community. The NINDS CDE Team has taken a systematic, iterative approach to develop the critical core and the disease-specific CDEs. The CDE development process provides a mechanism for community involvement and buy-in, offers a structure for decision making, and includes a technical support team. Upon conclusion of the development process, the CDEs and accompanying tools are available on the Project Web site - http://www.commondataelements.ninds.nih.gov/. The Web site currently includes the critical core (aka general) CDEs that are applicable to all clinical research studies regardless of therapeutic area as well as several disease-specific CDEs. Additional disease-specific CDEs will be added to the Web site once they are developed and vetted over the next 12 months. The CDEs will continue to evolve and will improve only if clinical researchers use and offer feedback about their experience with them. Thus, the NINDS program staff strongly encourages its clinical research grantees to use the CDEs and is expanding its efforts to educate the neuroscience research community

  18. Communication and computing technology in biocontainment laboratories using the NEIDL as a model.

    PubMed

    McCall, John; Hardcastle, Kath

    2014-07-01

    The National Emerging Infectious Diseases Laboratories (NEIDL), Boston University, is a globally unique biocontainment research facility housing biosafety level 2 (BSL-2), BSL-3, and BSL-4 laboratories. Located in the BioSquare area at the University's Medical Campus, it is part of a national network of secure facilities constructed to study infectious diseases of major public health concern. The NEIDL allows for basic, translational, and clinical phases of research to be carried out in a single facility with the overall goal of accelerating understanding, treatment, and prevention of infectious diseases. The NEIDL will also act as a center of excellence providing training and education in all aspects of biocontainment research. Within every detail of NEIDL operations is a primary emphasis on safety and security. The ultramodern NEIDL has required a new approach to communications technology solutions in order to ensure safety and security and meet the needs of investigators working in this complex building. This article discusses the implementation of secure wireless networks and private cloud computing to promote operational efficiency, biosecurity, and biosafety with additional energy-saving advantages. The utilization of a dedicated data center, virtualized servers, virtualized desktop integration, multichannel secure wireless networks, and a NEIDL-dedicated Voice over Internet Protocol (VoIP) network are all discussed. © 2014 Federation of European Microbiological Societies. Published by John Wiley & Sons Ltd. All rights reserved.

  19. Irregular Warfare as a National Military Strategy Approach for Small States

    DTIC Science & Technology

    2013-12-01

    the most effective strategy for them. Analyses of large numbers of historical cases show that a conventional approach is a road to defeat for...this thesis is to illuminate the potential for small states to improve the effect of their military by adopting an irregular strategy. The thesis is... effective strategy for them. Analyses of large numbers of historical cases show that a conventional approach is a road to defeat for small states

  20. A support vector machine approach to the automatic identification of fluorescence spectra emitted by biological agents

    NASA Astrophysics Data System (ADS)

    Gelfusa, M.; Murari, A.; Lungaroni, M.; Malizia, A.; Parracino, S.; Peluso, E.; Cenciarelli, O.; Carestia, M.; Pizzoferrato, R.; Vega, J.; Gaudio, P.

    2016-10-01

    Two of the major new concerns of modern societies are biosecurity and biosafety. Several biological agents (BAs) such as toxins, bacteria, viruses, fungi and parasites are able to cause damage to living systems either humans, animals or plants. Optical techniques, in particular LIght Detection And Ranging (LIDAR), based on the transmission of laser pulses and analysis of the return signals, can be successfully applied to monitoring the release of biological agents into the atmosphere. It is well known that most of biological agents tend to emit specific fluorescence spectra, which in principle allow their detection and identification, if excited by light of the appropriate wavelength. For these reasons, the detection of the UVLight Induced Fluorescence (UV-LIF) emitted by BAs is particularly promising. On the other hand, the stand-off detection of BAs poses a series of challenging issues; one of the most severe is the automatic discrimination between various agents which emit very similar fluorescence spectra. In this paper, a new data analysis method, based on a combination of advanced filtering techniques and Support Vector Machines, is described. The proposed approach covers all the aspects of the data analysis process, from filtering and denoising to automatic recognition of the agents. A systematic series of numerical tests has been performed to assess the potential and limits of the proposed methodology. The first investigations of experimental data have already given very encouraging results.

  1. A Multidisciplinary Approach to Decommissioning Offshore Wells Using Stakeholder Engagement, Risk Identification, and the United Nations Sustainable Development Goals

    NASA Astrophysics Data System (ADS)

    Battalora, L.; Prasad, M.

    2017-12-01

    A multidisciplinary approach using stakeholder engagement and risk identification tools and the United Nations Sustainable Development Goals is recommended for designing the decommissioning program of offshore wells. This recommendation also applies to onshore decommissioning programs.

  2. Estimating the National Carbon Abatement Potential of City Policies: A Data-Driven Approach

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    O'Shaughnessy, Eric; Heeter, Jenny; Keyser, David

    Cities are increasingly taking actions such as building code enforcement, urban planning, and public transit expansion to reduce emissions of carbon dioxide in their communities and municipal operations. However, many cities lack the quantitative information needed to estimate policy impacts and prioritize city actions in terms of carbon abatement potential and cost effectiveness. This report fills this research gap by providing methodologies to assess the carbon abatement potential of a variety of city actions. The methodologies are applied to an energy use data set of 23,458 cities compiled for the U.S. Department of Energy City Energy Profile tool. The analysismore » develops a national estimate of the carbon abatement potential of realizable city actions in six specific policy areas encompassing the most commonly implemented city actions. The results of this analysis suggest that, in aggregate, cities could reduce nationwide carbon emissions by about 210 million metric tons of carbon dioxide (MMT CO2) per year in a 'moderate abatement scenario' by 2035 and 480 MMT CO2/year in a 'high abatement scenario' by 2035 through these common actions typically within a city's control in the six policy areas. The aggregate carbon abatement potential of these specific areas equates to a reduction of 3%-7% relative to 2013 U.S. emissions. At the city level, the results suggest the average city could reduce carbon emissions by 7% (moderate) to 19% (high) relative to current city-level emissions. In the context of U.S. climate commitments under the 21st session of the Conference of the Parties (COP21), the estimated national abatement potential of the city actions analyzed in this report equates to about 15%-35% of the remaining carbon abatement necessary to achieve the U.S. COP21 target. Additional city actions outside the scope of this report, such as community choice aggregation (city-level purchasing of renewable energy), zero energy districts, and multi-level governance

  3. National Human Adipose Tissue Survey (Nhats)

    EPA Science Inventory

    Background:

    The U.S. Environmental Protection Agency (EPA)'s National Human Monitoring Program (NHMP), established by the U.S. Public Health Service in 1967, used an exposure-based approach to assess human exposure to toxic substances. Its primary component was the Natio...

  4. Planning for population viability on Northern Great Plains national grasslands

    USGS Publications Warehouse

    Samson, F.B.; Knopf, F.L.; McCarthy, C.W.; Noon, B.R.; Ostlie, W.R.; Rinehart, S.M.; Larson, S.; Plumb, G.E.; Schenbeck, G.L.; Svingen, D.N.; Byer, T.W.

    2003-01-01

    Broad-scale information in concert with conservation of individual species must be used to develop conservation priorities and a more integrated ecosystem protection strategy. In 1999 the United States Forest Service initiated an approach for the 1.2× 106 ha of national grasslands in the Northern Great Plains to fulfill the requirement to maintain viable populations of all native and desirable introduced vertebrate and plant species. The challenge was threefold: 1) develop basic building blocks in the conservation planning approach, 2) apply the approach to national grasslands, and 3) overcome differences that may exist in agency-specific legal and policy requirements. Key assessment components in the approach included a bioregional assessment, coarse-filter analysis, and fine-filter analysis aimed at species considered at-risk. A science team of agency, conservation organization, and university personnel was established to develop the guidelines and standards and other formal procedures for implementation of conservation strategies. Conservation strategies included coarse-filter recommendations to restore the tallgrass, mixed, and shortgrass prairies to conditions that approximate historical ecological processes and landscape patterns, and fine-filter recommendations to address viability needs of individual and multiple species of native animals and plants. Results include a cost-effective approach to conservation planning and recommendations for addressing population viability and biodiversity concerns on national grasslands in the Northern Great Plains.

  5. Understanding animal health communication networks among smallholder livestock producers in Australia using stakeholder analysis.

    PubMed

    Hayes, L; Woodgate, R; Rast, L; Toribio, J-A L M L; Hernández-Jover, M

    2017-09-01

    Smallholder livestock producers are a diverse population with wide ranging motivations for keeping livestock. The biosecurity risk posed by smallholders has been the subject of much conjecture, with comparisons often made between the level of animal health and biosecurity knowledge of smallholders, versus that of commercial livestock producers. This research aimed to gain a better understanding of current knowledge of smallholder production in Australia, particularly in relation to biosecurity and emergency animal disease, and to investigate the relationships that exist between smallholders and the organisations and individuals from which they seek information, assistance and support. Engagement with stakeholders is an important component of an effective biosecurity communication strategy as the dissemination of biosecurity related information from a single source cannot be expected to satisfy the needs of such a broad ranging population. A qualitative study involving a review of literature, semi-structured interviews with government and non-government stakeholders and the development of smallholder and stakeholder influence and interest grids was undertaken. This paper forms part of a broader mixed methods research project among smallholders. Results from the stakeholder analysis showed variation in the parameters used to define smallholders and in the level of stakeholder involvement. Smallholders identified breeding consultants, other producers, private veterinarians and family, friends and colleagues as having a significant to high level of interest and potential to influence their practices. Government agencies were perceived to only have some level of interest but significant influence. Industry stakeholders and rural suppliers were positioned in the quadrant reflecting perceived low levels of interest and influence. The interest and influence grid developed from stakeholder's perspectives demonstrate a clustering around the mid points for both interest and

  6. Lab Plays Central Role in Groundbreaking National Clinical Trial in Precision Medicine | Frederick National Laboratory for Cancer Research

    Cancer.gov

    The Molecular Characterization Laboratory at the Frederick National Laboratory for Cancer Research lies at the heart of an ambitious new approach for testing cancer drugs that will use the newest tools of precision medicine to select the best treatme

  7. Risk factors associated with infectious bursal disease vaccination failures in broiler farms in Kenya.

    PubMed

    Mutinda, Wanzila Usyu; Nyaga, Philip Njeru; Mbuthia, Paul Gichohi; Bebora, Lilly Caroline; Muchemi, Gerald

    2014-04-01

    Immunization together with application of biosecurity measures are the principal methods of preventing infectious bursal disease outbreaks in high-risk areas. However, outbreaks in vaccinated chicken flocks have been reported in many parts of the world as a result of factors of vaccine virus, animal, or vaccine handler. In Kenya, such outbreaks have been reported, but the causes have not been studied. This study aimed at determining the risk factors associated with vaccine handling leading to vaccine failure in broiler flocks in Kwale County, Kenya. Structured questionnaires and visual observations were used to collect data from 83 broiler farms, 6 breeding farms, and 17 vaccine outlets. Relative risk (RR) analysis was used to determine the association between identified potential risk factors and vaccination failure. Results show that vaccines were properly handled in all vaccine outlet shops. Breeding farms maintained high levels of biosecurity and employed standard vaccine handling practices. Basic biosecurity practices were poor in broiler farms. Broiler farms failed to meet all the recommended standard procedures for vaccine storage, reconstitution, and administration. Risk factors included poor vaccine storage (RR = 8.7) and use of few drinkers to administer vaccine (RR = 5.8); traces of disinfectants in drinkers used to administer live vaccine (RR = 2.8); use of wrong vaccine-infectious bronchitis instead of infectious bursal disease vaccine (RR = 2.1); and use of improper diluents (RR = 1.6). Broiler farmers need training on basic farm biosecurity measures and standard vaccine handling practices.

  8. EVALUATION OF EXPOSURE MEASUREMENT METHODS AND APPROACHES FOR THE NATIONAL CHILDREN'S STUDY

    EPA Science Inventory

    Several hypotheses have been proposed for the National Children's Study to examine the role of environmental exposures to chemical pollutants in health outcomes including asthma and impaired neurobehaviorial or neurocognitive function. To address these hypotheses, it will be nec...

  9. Seeing Charters Differently: A New Approach to National Comparisons of Charter and Traditional Public Schools

    ERIC Educational Resources Information Center

    Malkus, Nat

    2016-01-01

    The national debate over charter schooling has become increasingly heated in 2016, driven by polarized narratives about the students charters typically serve. Opponents argue charters cream-skim more advantaged students, while proponents hold they primarily serve historically disadvantaged students. National evidence on charter student selectivity…

  10. NATIONAL INSTITUTIONS AND SUBNATIONAL DEVELOPMENT IN AFRICA*

    PubMed Central

    Michalopoulos, Stelios; Papaioannou, Elias

    2014-01-01

    We investigate the role of national institutions on subnational African development in a novel framework that accounts for both local geography and cultural-genetic traits. We exploit the fact that the political boundaries on the eve of African independence partitioned more than 200 ethnic groups across adjacent countries subjecting similar cultures, residing in homogeneous geographic areas, to different formal institutions. Using both a matching type and a spatial regression discontinuity approach we show that differences in countrywide institutional structures across the national border do not explain within-ethnicity differences in economic performance, as captured by satellite images of light density. The average noneffect of national institutions on ethnic development masks considerable heterogeneity partially driven by the diminishing role of national institutions in areas further from the capital cities. PMID:25802926

  11. Contextualizing Obesity and Diabetes Policy: Exploring a Nested Statistical and Constructivist Approach at the Cross-National and Subnational Government Level in the United States and Brazil

    PubMed Central

    Gómez, Eduardo J.

    2017-01-01

    Background: This article conducts a comparative national and subnational government analysis of the political, economic, and ideational constructivist contextual factors facilitating the adoption of obesity and diabetes policy. Methods: We adopt a nested analytical approach to policy analysis, which combines cross-national statistical analysis with subnational case study comparisons to examine theoretical prepositions and discover alternative contextual factors; this was combined with an ideational constructivist approach to policy-making. Results: Contrary to the existing literature, we found that with the exception of cross-national statistical differences in access to healthcare infrastructural resources, the growing burden of obesity and diabetes, rising healthcare costs and increased citizens’ knowledge had no predictive affect on the adoption of obesity and diabetes policy. We then turned to a subnational comparative analysis of the states of Mississippi in the United States and Rio Grande do Norte in Brazil to further assess the importance of infrastructural resources, at two units of analysis: the state governments versus rural municipal governments. Qualitative evidence suggests that differences in subnational healthcare infrastructural resources were insufficient for explaining policy reform processes, highlighting instead other potentially important factors, such as state-civil societal relationships and policy diffusion in Mississippi, federal policy intervention in Rio Grande do Norte, and politicians’ social construction of obesity and the resulting differences in policy roles assigned to the central government. Conclusion: We conclude by underscoring the complexity of subnational policy responses to obesity and diabetes, the importance of combining resource and constructivist analysis for better understanding the context of policy reform, while underscoring the potential lessons that the United States can learn from Brazil. PMID:29179290

  12. [Biological research and security institutes].

    PubMed

    Darsie, G; Falczuk, A J; Bergmann, I E

    2006-04-01

    The threat of using biological material for ago-bioterrorist ends has risen in recent years, which means that research and diagnostic laboratories, biological agent banks and other institutions authorised to carry out scientific activities have had to implement biosafety and biosecurity measures to counter the threat, while carrying out activities to help prevent and monitor the accidental or intentional introduction of exotic animal diseases. This article briefly sets outthe basic components of biosafety and biosecurity, as well as recommendations on organisational strategies to consider in laboratories that support agro-bioterrorist surveillance and prevention programs.

  13. Integrating rangeland and pastureland assessment methods into a national grazingland assessment approach

    USDA-ARS?s Scientific Manuscript database

    Grazingland resource allocation and decision making at the national scale need to be based on comparable metrics. However, in the USA, rangelands and pasturelands have traditionally been assessed using different methods and indicators. These differences in assessment methods limit the ability to con...

  14. Uniform National Discharge Standards (UNDS): Fact Sheet

    EPA Pesticide Factsheets

    The factsheet describes the Uniform National Discharge Standards and explains what vessels are regulated and how the rulemaking will impact states. It details the batch and phase approach to rulemaking and lists the first batch of vessel discharges.

  15. First Nations Approaches to Childhood Obesity: Healthy Lifestyles in Canada Compared with Alternatives for Alaska Native Communities

    PubMed Central

    de Schweinitz, Peter A.; Wojcicki, Janet M.

    2017-01-01

    Alaska Native and American Indian children have among the highest prevalence of obesity in the United States. Canadian Aboriginal populations including First Nations also have high rates of obesity but obesity rates among children are noticeably lower. We highlight some of the important differences between American and Canadian approaches to healthy lifestyles and Aboriginal/Native health, including diet and physical activity, which may in part explain the differences in obesity prevalence. Specifically, the Canadian government provides a food subsidy program to bring perishable fruits and vegetable to remote, rural Canadian areas and secondly supports the use of traditional foods and harvesting/gathering through a number of government supported programs. Lastly, there may be a better sense of community and overall life satisfaction for Aboriginals compared with Alaska Natives, in part because of the incorporation of healthcare and other services within the larger overall community, as opposed to separate services as is the case for Alaska Natives. This perspective provides insight into some of these potential differences. PMID:28492517

  16. National Institutes of Health addresses the science of diversity

    PubMed Central

    Valantine, Hannah A.; Collins, Francis S.

    2015-01-01

    The US biomedical research workforce does not currently mirror the nation’s population demographically, despite numerous attempts to increase diversity. This imbalance is limiting the promise of our biomedical enterprise for building knowledge and improving the nation’s health. Beyond ensuring fairness in scientific workforce representation, recruiting and retaining a diverse set of minds and approaches is vital to harnessing the complete intellectual capital of the nation. The complexity inherent in diversifying the research workforce underscores the need for a rigorous scientific approach, consistent with the ways we address the challenges of science discovery and translation to human health. Herein, we identify four cross-cutting diversity challenges ripe for scientific exploration and opportunity: research evidence for diversity’s impact on the quality and outputs of science; evidence-based approaches to recruitment and training; individual and institutional barriers to workforce diversity; and a national strategy for eliminating barriers to career transition, with scientifically based approaches for scaling and dissemination. Evidence-based data for each of these challenges should provide an integrated, stepwise approach to programs that enhance diversity rapidly within the biomedical research workforce. PMID:26392553

  17. Writing Stories to Enhance Scientific Literacy

    NASA Astrophysics Data System (ADS)

    Ritchie, Stephen M.; Tomas, Louisa; Tones, Megan

    2011-03-01

    In response to international concerns about scientific literacy and students' waning interest in school science, this study investigated the effects of a science-writing project about the socioscientific issue (SSI) of biosecurity on the development of students' scientific literacy. Students generated two BioStories each that merged scientific information with the narrative storylines in the project. The study was conducted in two phases. In the exploratory phase, a qualitative case study of a sixth-grade class involving classroom observations and interviews informed the design of the second, confirmatory phase of the study, which was conducted at a different school. This phase involved a mixed methods approach featuring a quasi-experimental design with two classes of Australian middle school students (i.e., sixth grade, 11 years of age, n = 55). The results support the argument that writing the sequence of stories helped the students become more familiar with biosecurity issues, develop a deeper understanding of related biological concepts, and improve their interest in science. On the basis of these findings, teachers should be encouraged to engage their students in the practice of writing about SSI in a way that integrates scientific information into narrative storylines. Extending the practice to older students and exploring additional issues related to writing about SSI are recommended for further research.

  18. Estimating the Economic Value of National Parks with Count Data Models Using On-Site, Secondary Data: The Case of the Great Sand Dunes National Park and Preserve

    NASA Astrophysics Data System (ADS)

    Heberling, Matthew T.; Templeton, Joshua J.

    2009-04-01

    We estimate an individual travel cost model for Great Sand Dunes National Park and Preserve (GSD) in Colorado using on-site, secondary data. The purpose of the on-site survey was to help the National Park Service better understand the visitors of GSD; it was not intended for a travel cost model. Variables such as travel cost and income were estimated based on respondents’ Zip Codes. Following approaches found in the literature, a negative binomial model corrected for truncation and endogenous stratification fit the data the best. We estimate a recreational benefit of U.S. 89/visitor/year or U.S. 54/visitor/24-h recreational day (in 2002 U.S. ). Based on the approach presented here, there are other data sets for national parks, preserves, and battlefields where travel cost models could be estimated and used to support National Park Service management decisions.

  19. EVALUATION OF EXPOSURE MEASUREMENT METHODS AND APPROACHES FOR THE NATIONAL CHILDREN'S STUDY

    EPA Science Inventory

    The National Children's Study (NCS) will examine the effects of environmental influences on the health and development of children in the United States. The study is being planned as a large, long-term effort that will explore a broad range of environmental factors, both helpful...

  20. A knowledge translation project on community-centred approaches in public health.

    PubMed

    Stansfield, J; South, J

    2018-03-01

    This article examines the development and impact of a national knowledge translation project aimed at improving access to evidence and learning on community-centred approaches for health and wellbeing. Structural changes in the English health system meant that knowledge on community engagement was becoming lost and a fragmented evidence base was seen to impact negatively on policy and practice. A partnership started between Public Health England, NHS England and Leeds Beckett University in 2014 to address these issues. Following a literature review and stakeholder consultation, evidence was published in a national guide to community-centred approaches. This was followed by a programme of work to translate the evidence into national strategy and local practice.The article outlines the key features of the knowledge translation framework developed. Results include positive impacts on local practice and national policy, for example adoption within National Institute for Health and Care Evidence (NICE) guidance and Local Authority public health plans and utilization as a tool for local audit of practice and commissioning. The framework was successful in its non-linear approach to knowledge translation across a range of inter-connected activity, built on national leadership, knowledge brokerage, coalition building and a strong collaboration between research institute and government agency.

  1. Overview of the National Ignition Campaign (NIC)

    NASA Astrophysics Data System (ADS)

    Moses, Edward

    2010-11-01

    The 192-beam National Ignition Facility (NIF) at Lawrence Livermore National Laboratory (LLNL) is now operational. NIF has conducted 192-beam implosion experiments with energies as high as 1.2 MJ and has also demonstrated the unprecedented energy and pulse shaping control required for ignition experiments. The successful commissioning of the NIF laser is the first step in demonstrating inertial confinement fusion (ICF) ignition in the laboratory. The NIF ignition program is executed via the National Ignition Campaign (NIC)---a partnership between Los Alamos National Laboratory, Lawrence Berkeley Laboratory, LLNL, General Atomics, the University of Rochester Laboratory for Laser Energetics, Sandia National Laboratories, the Massachusetts Institute of Technology, and other national and international partners. The NIC relies on a novel integrated experimental and computational program to tune the target to the conditions required for indirect-drive ignition. This approach breaks the tuning process into four phases. The first two phases involve tuning of the hohlraum and capsule to produce the correct radiation drive, symmetry, and shock timing conditions. The third phase consists of layered cryogenic implosions conducted with a 50%/49%/1% mixture of tritium, hydrogen, and deuterium (THD) respectively. The reduced yield from these THD targets allows the full diagnostic suite to be employed and the presence of the required temperature and fuel areal density to be verified. The final step is DT ignition implosions with expected gains of 10-20. DT ignition experiments will be conducted with Elaser ˜1.2 MJ. Laser energies of 1.8 MJ should be available for subsequent experiments. This talk will review the multi-phase tuning approach to the ignition effort, including the physics issues associated with the various steps, and current and future plans for the NIF ignition program.

  2. Professionalizing the Nation's Cybersecurity Workforce?: Criteria for Decision-Making

    ERIC Educational Resources Information Center

    National Academies Press, 2013

    2013-01-01

    "Professionalizing the Nation's Cybersecurity Workforce? Criteria for Decision-Making" considers approaches to increasing the professionalization of the nation's cybersecurity workforce. This report examines workforce requirements for cybersecurity and the segments and job functions in which professionalization is most needed;…

  3. Control strategies for highly pathogenic avian influenza: a global perspective.

    PubMed

    Lubroth, J

    2007-01-01

    Comprehensive programmes for the prevention, detection and control of highly pathogenic avian influenza (HPAI) require a national dimension and relevant national legislation in which veterinary services can conduct surveillance, competent diagnosis and rapid response. Avian influenza was controlled and prevented by vaccination long before the current H5N1 crisis. The use of vaccine cannot be separated from other essential elements of a vaccination campaign, which include education in poultry production practices, such as hygiene, all in-all out production concepts, separation of species, biosecurity (bio-exclusion to keep the disease out and biocontainment to keep the disease from spreading once suspected or detected), competence in giving the vaccine and the role of vaccination teams, post-vaccination monitoring to ensure efficacy and to detect the circulation of wild-type virus, surveillance and buffer zones in outbreak areas, and performance indicators to determine when vaccination can cease. Reporting of disease can be improved through well-structured, adequately financed veterinary services and also by fair compensation for producers who suffer financial loss. A rapid response to suspected cases of HPAI should be ensured in simulation exercises involving various sectors of the food production and marketing chain, policy-makers, official veterinary structures and other government personnel. As for other transboundary animal diseases, national approaches must be part of a regional strategy and regional networks for cooperation and information sharing, which in turn reflect global policies and international standards, such as the quality of vaccines, reporting obligations, humane interventions, cleaning and disinfection methods, restocking times, monitoring and safe trade.

  4. Comparison of Remote Sensing and Fixed-Site Monitoring Approaches for Examining Air Pollution and Health in a National Study Population

    NASA Technical Reports Server (NTRS)

    Prud'homme, Genevieve; Dobbin, Nina A.; Sun, Liu; Burnet, Richard T.; Martin, Randall V.; Davidson, Andrew; Cakmak, Sabit; Villeneuve, Paul J.; Lamsal, Lok N.; vanDonkelaar, Aaron; hide

    2013-01-01

    Satellite remote sensing (RS) has emerged as a cutting edge approach for estimating ground level ambient air pollution. Previous studies have reported a high correlation between ground level PM2.5 and NO2 estimated by RS and measurements collected at regulatory monitoring sites. The current study examined associations between air pollution and adverse respiratory and allergic health outcomes using multi-year averages of NO2 and PM2.5 from RS and from regulatory monitoring. RS estimates were derived using satellite measurements from OMI, MODIS, and MISR instruments. Regulatory monitoring data were obtained from Canada's National Air Pollution Surveillance Network. Self-reported prevalence of doctor-diagnosed asthma, current asthma, allergies, and chronic bronchitis were obtained from the Canadian Community Health Survey (a national sample of individuals 12 years of age and older). Multi-year ambient pollutant averages were assigned to each study participant based on their six digit postal code at the time of health survey, and were used as a marker for long-term exposure to air pollution. RS derived estimates of NO2 and PM2.5 were associated with 6e10% increases in respiratory and allergic health outcomes per interquartile range (3.97 mg m3 for PM2.5 and 1.03 ppb for NO2) among adults (aged 20e64) in the national study population. Risk estimates for air pollution and respiratory/ allergic health outcomes based on RS were similar to risk estimates based on regulatory monitoring for areas where regulatory monitoring data were available (within 40 km of a regulatory monitoring station). RS derived estimates of air pollution were also associated with adverse health outcomes among participants residing outside the catchment area of the regulatory monitoring network (p < 0.05).

  5. Integrated Nationwide Electronic Health Records system: Semi-distributed architecture approach.

    PubMed

    Fragidis, Leonidas L; Chatzoglou, Prodromos D; Aggelidis, Vassilios P

    2016-11-14

    The integration of heterogeneous electronic health records systems by building an interoperable nationwide electronic health record system provides undisputable benefits in health care, like superior health information quality, medical errors prevention and cost saving. This paper proposes a semi-distributed system architecture approach for an integrated national electronic health record system incorporating the advantages of the two dominant approaches, the centralized architecture and the distributed architecture. The high level design of the main elements for the proposed architecture is provided along with diagrams of execution and operation and data synchronization architecture for the proposed solution. The proposed approach effectively handles issues related to redundancy, consistency, security, privacy, availability, load balancing, maintainability, complexity and interoperability of citizen's health data. The proposed semi-distributed architecture offers a robust interoperability framework without healthcare providers to change their local EHR systems. It is a pragmatic approach taking into account the characteristics of the Greek national healthcare system along with the national public administration data communication network infrastructure, for achieving EHR integration with acceptable implementation cost.

  6. Safeguards Knowledge Management & Retention at U.S. National Laboratories.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Haddal, Risa; Jones, Rebecca; Bersell, Bridget

    In 2017, four U.S. National Laboratories collaborated on behalf of DOE/NNSA to explore the safeguards knowledge retention problem, identify possible approaches, and develop a strategy to address it. The one-year effort consisted of four primary tasks. First, the project sought to identify critical safeguards information at risk of loss. Second, a survey and workshop were conducted to assess nine U.S. National Laboratories' efforts to determine current safeguards knowledge retention practices and challenges, and identify best practices. Third, specific tools were developed to identify and predict critical safeguards knowledge gaps and how best to recruit in order to fill those gaps.more » Finally, based on findings from the first three tasks and research on other organizational approaches to address similar issues, a strategy was developed on potential knowledge retention methods, customized HR policies, and best practices that could be implemented across the National Laboratory Complex.« less

  7. NASA's Space Launch System (SLS): A New National Capability

    NASA Technical Reports Server (NTRS)

    May, Todd A.

    2012-01-01

    The National Aeronautics and Space Administration's (NASA's) Space Launch System (SLS) will contribute a new national capability for human space flight and scientific missions to low- Earth orbit (LEO) and beyond. Exploration beyond Earth orbit will be an enduring legacy to future generations, confirming America s desire to explore, learn, and progress. The SLS Program, managed at NASA s Marshall Space Fight Center, will develop the heavy lift vehicle that will launch the Orion Multi-Purpose Crew Vehicle (MPCV), equipment, supplies, and science experiments for missions beyond Earth s orbit. This paper gives an overview of the SLS design and management approach against a backdrop of the missions it will empower. It will detail the plan to move from the computerized drawing board to the launch pad in the near term, as well as summarize the innovative approaches the SLS team is applying to deliver a safe, affordable, and sustainable long-range national capability.

  8. Marketing national parks: oxymoron or opportunity?

    Treesearch

    Alan K. Hogenauer

    2002-01-01

    Although the "national park" concept is universally acknowledged, marketing of the 4,000+ areas so designated worldwide varies dramatically. Some park systems - such as those of Canada and Australia ? are extensively marketed, in the sense that considerable resources are devoted to traditional strategic and tactical approaches to the potential user. Other...

  9. Deconstructing national leadership: politicians' accounts of electoral success and failure in the Irish Lisbon Treaty referenda.

    PubMed

    Burns, Michele; Stevenson, Clifford

    2013-03-01

    The Self Categorization approach to national leadership proposes that leaders rhetorically construct national identity as essentialized and inevitable in order to consensualize and mobilize the population. In contrast, discursive studies have demonstrated how national politicians flexibly construct the nation to manage their own accountability in local interactions, though this in turn has neglected broader leadership processes. The present paper brings both approaches together to examine how and when national politicians construct versions of national identity in order to account for their failure as well as success in mobilizing the electorate. Eight semi-structured conversational style interviews were conducted with a strategic sample of eight leading Irish politicians on the subject of the 2008/2009 Irish Lisbon Treaty referenda. Using a Critical Discourse Psychology approach, the hegemonic repertoire of the 'settled will' of the informed and consensualized Irish nation was identified across all interviews. Politicians either endorsed the 'settled will' repertoire as evidence of their successful leadership, or rejected the repertoire by denying the rationality or unity of the populace to account for their failure. Our results suggest national identity is only constructed as essentialized and inevitable to the extent that it serves a strategic political purpose. © 2011 The British Psychological Society.

  10. Cross-continental comparison of national food consumption survey methods--a narrative review

    USDA-ARS?s Scientific Manuscript database

    Food consumption surveys are performed in many countries. Comparison of results from those surveys across nations is difficult because of differences in methodological approaches. While consensus about the preferred methodology associated with national food consumption surveys is increasing, no in...

  11. The National Action Plan To Implement the Hydrogeomorphic Approach To Assessing Wetland Functions

    EPA Pesticide Factsheets

    Full text of Federal Register notice. The strategy the Corps and other Federal agencies will follow to implement the Hydrogeomorphic Approach for Assessing Wetland Functions (HGM Approach) through the development of regional guidebooks.

  12. [Viral biosafety, biosecurity, and bioterrorism].

    PubMed

    Garin, D

    2010-02-01

    Intentional release of infectious agents has always been considered as a possible weapon. Today this risk has expanded from use for wartime mass destruction to small-scale terrorist acts. Viruses, some of tropical origin, constitute a special biological hazard for several reasons: great infectious potential, adaptability to the host, difficulty for diagnosis in the hospital, and absence of specific treatment for the main agents involved. Handling of the dangerous biological agents requires special biocontainment laboratories equipped and classified according to increasing risk up to level 4. This article discusses the modalities of classification.

  13. Ethics in biotechnology and biosecurity.

    PubMed

    Jameel, S

    2011-01-01

    Great advances in technology produce unique challenges. Every technology also has a dual use, which needs to be understood and managed to extract maximum benefits for mankind and the development of civilization. The achievements of physicists in the mid-20th century resulted in the nuclear technology, which gave us the destructive power of the atomic bomb as also a source of energy. Towards the later part of the 20th century, information technology empowered us with fast, easy and cheap access to information, but also led to intrusions into our privacy. Today, biotechnology is yielding life- saving and life-enhancing advances at a fast pace. But, the same tools can also give rise to fiercely destructive forces. How do we construct a security regime for biology? What have we learnt from the management of earlier technological advances? How much information should be in the public domain? Should biology, or more broadly science, be regulated? Who should regulate it? These and many other ethical questions need to be addressed.

  14. A National Approach to Quantify and Map Biodiversity ...

    EPA Pesticide Factsheets

    Ecosystem services, i.e., "services provided to humans from natural systems," have become a key issue of this century in resource management, conservation planning, human well-being, and environmental decision analysis. Mapping and quantifying ecosystem services have become strategic national interests for integrating ecology with economics to help understand the effects of human policies and actions and their subsequent impacts on both ecosystem function and human welfare. The degradation of natural ecosystems and climate variation impact the environment and society by affecting ecological integrity and ecosystems’ capacity to provide critical services (i.e., the contributions of ecosystems to human well-being). These challenges will require complex management decisions that can often involve significant trade-offs between societal desires and environmental needs. Evaluating trade-offs in terms of ecosystem services and human well-being provides an intuitive and comprehensive way to assess the broad implications of our decisions and to help shape policies that enhance environmental and social sustainability. In answer to this challenge, the U.S. government has created a partnership among the U.S. Environmental Protection Agency, other Federal agencies, academic institutions, and, Non-Governmental Organizations to develop the EnviroAtlas, an online Decision Support Tool that allows users (e.g., planners, policy-makers, resource managers, NGOs, private indu

  15. Guitars and Makerspace: Examining the Experience of First Nations Students

    ERIC Educational Resources Information Center

    Wilson, Jay; Gobeil, Marc

    2017-01-01

    This research project examined the impact on student engagement of a makerspace approach in an all-First Nations high school. First Nations learners have many factors limiting their success in the K-12 system such as lack of connection to the curriculum, limited cultural relevance of course content, and poor attendance. A common concern for those…

  16. Information systems analysis approach in hospitals: a national survey.

    PubMed

    Wong, B K; Sellaro, C L; Monaco, J A

    1995-03-01

    A survey of 216 hospitals reveals that some hospitals do not conduct cost-benefit analyses or analyze possible adverse effects in feasibility studies. In determining and analyzing system requirements, external factors that initiate the transaction are not examined, and computer-aided software engineering (CASE) tools are seldom used. Some hospitals do not investigate the advantages and disadvantages of using in-house-developed software versus purchased software packages in the evaluation of alternatives. The survey finds that, overall, most hospitals follow the traditional systems development life cycle (SDLC) approach in analyzing information systems.

  17. Practical considerations for disaster preparedness and continuity management in research facilities.

    PubMed

    Mortell, Norman; Nicholls, Sam

    2013-10-01

    Many research facility managers, veterinarians and directors are familiar with the principles of Good Laboratory Practice, requirements of the Association for Assessment and Accreditation of Laboratory Animal Care International, tenets of biosecurity and standards of animal welfare and housing but may be less familiar with the ideas of business continuity. But business continuity considerations are as applicable to research facilities as they are to other institutions. The authors discuss how business continuity principles can be applied in the research context and propose that such application, or 'research continuity management,' enables a focused but wide-reaching approach to disaster preparedness.

  18. Dynamic traffic assignment : genetic algorithms approach

    DOT National Transportation Integrated Search

    1997-01-01

    Real-time route guidance is a promising approach to alleviating congestion on the nations highways. A dynamic traffic assignment model is central to the development of guidance strategies. The artificial intelligence technique of genetic algorithm...

  19. National estimates of soil loss on rangelands

    USDA-ARS?s Scientific Manuscript database

    Since 1995, an interagency group composed of the Natural Resources Conservation Service, Agricultural Research Service, and U.S. Geological Survey have worked together to develop a robust field approach for National Resource Inventory (NRI) on rangeland. The new NRI protocols are designed to detect ...

  20. Wetland Hydrologic Connectivity to Downstream Waters: A Classification Approach and National Assessment

    NASA Astrophysics Data System (ADS)

    Leibowitz, S. G.; Hill, R. A.; Weber, M.; Jones, C., Jr.; Rains, M. C.; Creed, I. F.; Christensen, J.

    2017-12-01

    Connectivity has become a major focus of hydrological and ecological studies. Connectivity enhances fluxes among landscape features, whereas isolation eliminates or reduces such flows. Thus connectivity can be an important characteristic controlling ecosystem services. Hydrologic connectivity is particularly significant, since chemical and biological flows are often associated with water movement. Wetlands have many important functions, and the degree to which they are hydrologically connected influences the effect they have on downstream waters. Wetlands with high connectivity can serve as sources (e.g., net exporters of dissolved organic carbon), while those with low connectivity can function as sinks (e.g., net importers of suspended sediments). We developed a system to classify wetlands based on type, magnitude, and frequency of hydrologic connectivity with downstream waters. We determined type (riparian, non-riparian surface, and non-riparian subsurface) by considering soil and bedrock permeability. For magnitude, we developed indices to represent travel time based on Manning's kinematic and Darcy's equations. We used soil drainage class as an indicator of frequency. We also included an index that assesses relative level of anthropogenic impacts to connectivity (e.g., presence of canals and ditches and impervious surfaces). The classification system was designed to be applied at various spatial scales using available data. The system was applied to 4.7 million wetlands in the conterminous United States, using the National Land Cover Dataset and other nationally available geospatial data, and the resulting maps were assessed for patterns in wetland connectivity. While wetland connectivity was dominated by fast, frequent riparian connections nationally, distributions of connectivity were characteristic for each region. Consideration of these distributions of connectivity should promote better management of watershed functions such as flood control and water

  1. A Socio-Ecological Approach for Identifying and Contextualising Spatial Ecosystem-Based Adaptation Priorities at the Sub-National Level

    PubMed Central

    Bourne, Amanda; Holness, Stephen; Holden, Petra; Scorgie, Sarshen; Donatti, Camila I.; Midgley, Guy

    2016-01-01

    Climate change adds an additional layer of complexity to existing sustainable development and biodiversity conservation challenges. The impacts of global climate change are felt locally, and thus local governance structures will increasingly be responsible for preparedness and local responses. Ecosystem-based adaptation (EbA) options are gaining prominence as relevant climate change solutions. Local government officials seldom have an appropriate understanding of the role of ecosystem functioning in sustainable development goals, or access to relevant climate information. Thus the use of ecosystems in helping people adapt to climate change is limited partially by the lack of information on where ecosystems have the highest potential to do so. To begin overcoming this barrier, Conservation South Africa in partnership with local government developed a socio-ecological approach for identifying spatial EbA priorities at the sub-national level. Using GIS-based multi-criteria analysis and vegetation distribution models, the authors have spatially integrated relevant ecological and social information at a scale appropriate to inform local level political, administrative, and operational decision makers. This is the first systematic approach of which we are aware that highlights spatial priority areas for EbA implementation. Nodes of socio-ecological vulnerability are identified, and the inclusion of areas that provide ecosystem services and ecological resilience to future climate change is innovative. The purpose of this paper is to present and demonstrate a methodology for combining complex information into user-friendly spatial products for local level decision making on EbA. The authors focus on illustrating the kinds of products that can be generated from combining information in the suggested ways, and do not discuss the nuance of climate models nor present specific technical details of the model outputs here. Two representative case studies from rural South Africa

  2. A Socio-Ecological Approach for Identifying and Contextualising Spatial Ecosystem-Based Adaptation Priorities at the Sub-National Level.

    PubMed

    Bourne, Amanda; Holness, Stephen; Holden, Petra; Scorgie, Sarshen; Donatti, Camila I; Midgley, Guy

    2016-01-01

    Climate change adds an additional layer of complexity to existing sustainable development and biodiversity conservation challenges. The impacts of global climate change are felt locally, and thus local governance structures will increasingly be responsible for preparedness and local responses. Ecosystem-based adaptation (EbA) options are gaining prominence as relevant climate change solutions. Local government officials seldom have an appropriate understanding of the role of ecosystem functioning in sustainable development goals, or access to relevant climate information. Thus the use of ecosystems in helping people adapt to climate change is limited partially by the lack of information on where ecosystems have the highest potential to do so. To begin overcoming this barrier, Conservation South Africa in partnership with local government developed a socio-ecological approach for identifying spatial EbA priorities at the sub-national level. Using GIS-based multi-criteria analysis and vegetation distribution models, the authors have spatially integrated relevant ecological and social information at a scale appropriate to inform local level political, administrative, and operational decision makers. This is the first systematic approach of which we are aware that highlights spatial priority areas for EbA implementation. Nodes of socio-ecological vulnerability are identified, and the inclusion of areas that provide ecosystem services and ecological resilience to future climate change is innovative. The purpose of this paper is to present and demonstrate a methodology for combining complex information into user-friendly spatial products for local level decision making on EbA. The authors focus on illustrating the kinds of products that can be generated from combining information in the suggested ways, and do not discuss the nuance of climate models nor present specific technical details of the model outputs here. Two representative case studies from rural South Africa

  3. The Cooperative Approach in Rural Development. A National Strategy and Program Design.

    ERIC Educational Resources Information Center

    Kelly, Rita Mae

    Building upon the body of knowledge re: rural cooperatives generated by the Office of Economic Opportunity and its research and demonstration programs, this paper proposes a design for a national program of Federal support for cooperatives serving the rural poor. Specifically, this paper presents: (1) the basic situation of the rural poor and the…

  4. Pioneering the Transdisciplinary Team Science Approach: Lessons Learned from National Cancer Institute Grantees

    PubMed Central

    Vogel, Amanda L; Stipelman, Brooke A; Hall, Kara L; Nebeling, Linda; Stokols, Daniel; Spruijt-Metz, Donna

    2014-01-01

    The National Cancer Institute has been a leader in supporting transdisciplinary (TD) team science. From 2005-2010, the NCI supported Transdisciplinary Research on Energetic and Cancer I (TREC I), a center initiative fostering the TD integration of social, behavioral, and biological sciences to examine the relationships among obesity, nutrition, physical activity and cancer. In the final year of TREC I, we conducted qualitative in-depth-interviews with 31 participating investigators and trainees to learn more about their experiences with TD team science, including challenges, facilitating factors, strategies for success, and impacts. Five main challenges emerged: (1) limited published guidance for how to engage in TD team science, when TREC I was implemented; (2) conceptual and scientific challenges inherent to efforts to achieve TD integration; (3) discipline-based differences in values, terminology, methods, and work styles; (4) project management challenges involved in TD team science; and (5) traditional incentive and reward systems that do not recognize or reward TD team science. Four main facilitating factors and strategies for success emerged: (1) beneficial attitudes and beliefs about TD research and team science; (2) effective team processes; (3) brokering and bridge-building activities by individuals holding particular roles in a research center; and (4) funding initiative characteristics that support TD team science. Broad impacts of participating in TD team science in the context of TREC I included: (1) new positive attitudes about TD research and team science; (2) new boundary-crossing collaborations; (3) scientific advances related to research approaches, findings, and dissemination; (4) institutional culture change and resource creation in support of TD team science; and (5) career advancement. Funding agencies, academic institutions, and scholarly journals can help to foster TD team science through funding opportunities, institutional policies on

  5. NSF in a Changing World: The National Science Foundation's Strategic Plan.

    ERIC Educational Resources Information Center

    National Science Foundation, Washington, DC.

    The National Science Foundation's (NSF) role as a leader and steward of the Nation's science and engineering enterprise faces new tests--promoting new approaches to research, education, and workforce training that reach all Americans; responding to the increased importance of science and engineering in many aspects of daily life; modernizing the…

  6. Disease and health management in Asian aquaculture.

    PubMed

    Bondad-Reantaso, Melba G; Subasinghe, Rohana P; Arthur, J Richard; Ogawa, Kazuo; Chinabut, Supranee; Adlard, Robert; Tan, Zilong; Shariff, Mohamed

    2005-09-30

    Asia contributes more than 90% to the world's aquaculture production. Like other farming systems, aquaculture is plagued with disease problems resulting from its intensification and commercialization. This paper describes the various factors, providing specific examples, which have contributed to the current disease problems faced by what is now the fastest growing food-producing sector globally. These include increased globalization of trade and markets; the intensification of fish-farming practices through the movement of broodstock, postlarvae, fry and fingerlings; the introduction of new species for aquaculture development; the expansion of the ornamental fish trade; the enhancement of marine and coastal areas through the stocking of aquatic animals raised in hatcheries; the unanticipated interactions between cultured and wild populations of aquatic animals; poor or lack of effective biosecurity measures; slow awareness on emerging diseases; the misunderstanding and misuse of specific pathogen free (SPF) stocks; climate change; other human-mediated movements of aquaculture commodities. Data on the socio-economic impacts of aquatic animal diseases are also presented, including estimates of losses in production, direct and indirect income and employment, market access or share of investment, and consumer confidence; food availability; industry failures. Examples of costs of investment in aquatic animal health-related activities, including national strategies, research, surveillance, control and other health management programmes are also provided. Finally, the strategies currently being implemented in the Asian region to deal with transboundary diseases affecting the aquaculture sector are highlighted. These include compliance with international codes, and development and implementation of regional guidelines and national aquatic animal health strategies; new diagnostic and therapeutic techniques and new information technology; new biosecurity measures including

  7. Association between Long-Term Exposure to Particulate Matter Air Pollution and Mortality in a South Korean National Cohort: Comparison across Different Exposure Assessment Approaches

    PubMed Central

    Kim, Sun-Young; Kim, Ho

    2017-01-01

    Increasing numbers of cohort studies have reported that long-term exposure to ambient particulate matter is associated with mortality. However, there has been little evidence from Asian countries. We aimed to explore the association between long-term exposure to particulate matter with a diameter ≤10 µm (PM10) and mortality in South Korea, using a nationwide population-based cohort and an improved exposure assessment (EA) incorporating time-varying concentrations and residential addresses (EA1). We also compared the association across different EA approaches. We used information from 275,337 people who underwent health screening from 2002 to 2006 and who had follow-up data for 12 years in the National Health Insurance Service-National Sample Cohort. Individual exposures were computed as 5-year averages using predicted residential district-specific annual-average PM10 concentrations for 2002–2006. We estimated hazard ratios (HRs) of non-accidental and five cause-specific mortalities per 10 µg/m3 increase in PM10 using the Cox proportional hazards model. Then, we compared the association of EA1 with three other approaches based on time-varying concentrations and/or addresses: predictions in each year and addresses at baseline (EA2); predictions at baseline and addresses in each year (EA3); and predictions and addresses at baseline (EA4). We found a marginal association between long-term PM10 and non-accidental mortality. The HRs of five cause-specific mortalities were mostly higher than that of non-accidental mortality, but statistically insignificant. In the comparison between EA approaches, the HRs of EA1 were similar to those of EA2 but higher than EA3 and EA4. Our findings confirmed the association between long-term exposure to PM10 and mortality based on a population-representative cohort in South Korea, and suggested the importance of assessing individual exposure incorporating air pollution changes over time. PMID:28946613

  8. National Disability Policy: A Progress Report

    ERIC Educational Resources Information Center

    National Council on Disability, 2009

    2009-01-01

    In recent years, the National Council on Disability (NCD) Progress Report has been a retrospective review and analysis of Federal programs for people with disabilities. For this Progress Report, NCD members have chosen to depart from a retrospective approach, and, instead, will focus on the current status of the quality of life of people with…

  9. Collection and production of indigenous plant material for national park restoration

    Treesearch

    Mark Majerus

    1999-01-01

    The National Park Service is taking the "Restoration" approach to reestablishing native plant communities by salvaging topsoil and by seeding and planting native indigenous plant materials. In this way, they are making every effort to protect the genetic integrity of the often unique native plant resource. Since 1985, Yellowstone and Glacier National Parks...

  10. National Quality Improvement Center on Early Childhood

    ERIC Educational Resources Information Center

    Browne, Charlyn Harper

    2014-01-01

    The national Quality Improvement Center on early Childhood (QIC-eC) funded four research and demonstration projects that tested child maltreatment prevention approaches. The projects were guided by several key perspectives: the importance of increasing protective factors in addition to decreasing risk factors in child maltreatment prevention…

  11. Validating a Spanish Version of the PIMRS: Application in National and Cross-National Research on Instructional Leadership

    ERIC Educational Resources Information Center

    Fromm, Germán; Hallinger, Philip; Volante, Paulo; Wang, Wen Chung

    2017-01-01

    The purposes of this study were to report on a systematic approach to validating a Spanish version of the Principal Instructional Management Rating Scale and then to apply the scale in a cross-national comparison of principal instructional leadership. The study yielded a validated Spanish language version of the PIMRS Teacher Form and offers a…

  12. The National Curriculum and Enabling Creativity

    ERIC Educational Resources Information Center

    Sawyer, Wayne

    2008-01-01

    Gunther Kress's call for a curriculum based on textual creation in a global era of instability is particularly appropriate to the present historical moment. Here I argue the need for a notion of creativity as the basis for a national curriculum in English. The kind of creativity envisaged issues out of a systems theory approach which sees…

  13. Status of national diabetes programmes in the Americas.

    PubMed Central

    White, F.; Nanan, D.

    1999-01-01

    Reported are the responses in the latter half of 1997 of all ministries of health in the Region of the Americas to the Declaration of the Americas on Diabetes, which was adopted by the Directing Council of the Pan American Health Organization (PAHO) in 1996 as a basis for national programme development in diabetes. The short-term targets were the designation of national focal points, the preparation of national estimates of the disease burden, and the development and implementation of national strategies and plans to deal with diabetes. The survey found that most countries recognized diabetes as a significant public health problem. In terms of global relevance, a number of lessons have been learned from this exercise: the role of broadly based participation in gaining recognition at the national health policy level; the wide acceptance of an integrated programme model; the relevance of process-related targets to achieve short-term success; and the critical role of having a designated focal point within the managerial approach. PMID:10680245

  14. Australia's national men's health policy: masculinity matters.

    PubMed

    Saunders, Margo; Peerson, Anita

    2009-08-01

    The development of Australia's first national men's health policy provides an important opportunity for informed discussions of health and gender. It is therefore a concern that the stated policy appears to deliberately exclude hegemonic masculinity and other masculinities, despite evidence of their major influence on men's health-related values, beliefs, perspectives, attitudes, motivations and behaviour. We provide an evidence-based critique of the proposed approach to a national men's health policy which raises important questions about whether the new policy can achieve its aims if it fails to acknowledge 'masculinity' as a key factor in Australian men's health. The national men's health policy should be a means to encourage gender analysis in health. This will require recognition of the influence of hegemonic masculinity, and other masculinities, on men's health. Recognising the influence of 'masculinity' on men's health is not about 'blaming' men for 'behaving badly', but is crucial to the development of a robust, meaningful and comprehensive national men's health policy.

  15. A framework for evaluating national space activity

    NASA Astrophysics Data System (ADS)

    Wood, Danielle; Weigel, Annalisa

    2012-04-01

    Space technology and resources are used around the world to address societal challenges. Space provides valuable satellite services, unique scientific discoveries, surprising technology applications and new economic opportunities. Many developing countries formally recognize the advantages of space resources and pursue national level activity to harness them. There is limited data or documentation on the space activities of developing countries. Meanwhile, traditional approaches to summarize national space activity do not necessarily capture the types of activity that developing countries pursue in space. This is especially true if they do not have a formal national space program or office. Developing countries pursue national space activity through activities of many types—from national satellite programs to commercial use of satellite services to involvement with international space institutions. This research aims to understand and analyze these trends. This paper introduces two analytical frameworks for evaluating space activity at the national level. The frameworks are specifically designed to capture the activity of countries that have traditionally been less involved in space. They take a broad view of space related activity across multiple societal sectors and disciplines. The discussion explains the approach for using the frameworks as well as illustrative examples of how they can be applied as part of a research process. The first framework is called the Mission and Management Ladders. This framework considers specific space projects within countries and ranks them on "Ladders" that measure technical challenge and managerial autonomy. This first method is at a micro level of analysis. The second framework is called the Space Participation Metric (SPM). The SPM can be used to assign a Space Participation score to countries based on their involvement in various space related activities. This second method uses a macro level of analysis. The authors

  16. Major Events Leading to Establishment of The National Task Bank.

    ERIC Educational Resources Information Center

    Upjohn (W.E.) Inst. for Employment Research, Washington, DC.

    This document describes how the plan for a National Task Bank evolved as part of an effort to encourage State and local public welfare agencies to adopt new approaches to staff planning and utilization. The task bank is an outgrowth of the application of systems approach and functional job analysis to agency management. Individualized data banks…

  17. Highway safety research : a national agenda : executive summary.

    DOT National Transportation Integrated Search

    2001-01-01

    Motor vehicle-related injury and death is the nations largest public health problem. The economic costs to society : will approach $2 trillion and an even greater intangible human loss will occur to family and friends of the 33 million : victims. :...

  18. The Italian Dementia National Plan. Commentary.

    PubMed

    Di Fiandra, Teresa; Canevelli, Marco; Di Pucchio, Alessandra; Vanacore, Nicola

    2015-01-01

    The Italian Dementia National Plan was formulated in October 2014 by the Italian Ministry of Health in close cooperation with the regions, the National Institute of Health and the three major national associations of patients and carers. The main purpose of this strategy was to provide directive indications for promoting and improving interventions in the dementia field, not limiting to specialist and therapeutic actions, but particularly focusing on the support of patients and families throughout the pathways of care. Four main objectives are indicated: 1) promote health- and social-care interventions and policies; 2) create/strengthen the integrated network of services for dementia based on an integrated approach; 3) implement strategies for promoting appropriateness and quality of care; and 4) improve the quality of life of persons with dementia and their families by supporting empowerment and stigma reduction. These objectives and the pertaining actions are described in the present paper.

  19. Ensemble streamflow assimilation with the National Water Model.

    NASA Astrophysics Data System (ADS)

    Rafieeinasab, A.; McCreight, J. L.; Noh, S.; Seo, D. J.; Gochis, D.

    2017-12-01

    Through case studies of flooding across the US, we compare the performance of the National Water Model (NWM) data assimilation (DA) scheme to that of a newly implemented ensemble Kalman filter approach. The NOAA National Water Model (NWM) is an operational implementation of the community WRF-Hydro modeling system. As of August 2016, the NWM forecasts of distributed hydrologic states and fluxes (including soil moisture, snowpack, ET, and ponded water) over the contiguous United States have been publicly disseminated by the National Center for Environmental Prediction (NCEP) . It also provides streamflow forecasts at more than 2.7 million river reaches up to 30 days in advance. The NWM employs a nudging scheme to assimilate more than 6,000 USGS streamflow observations and provide initial conditions for its forecasts. A problem with nudging is how the forecasts relax quickly to open-loop bias in the forecast. This has been partially addressed by an experimental bias correction approach which was found to have issues with phase errors during flooding events. In this work, we present an ensemble streamflow data assimilation approach combining new channel-only capabilities of the NWM and HydroDART (a coupling of the offline WRF-Hydro model and NCAR's Data Assimilation Research Testbed; DART). Our approach focuses on the single model state of discharge and incorporates error distributions on channel-influxes (overland and groundwater) in the assimilation via an ensemble Kalman filter (EnKF). In order to avoid filter degeneracy associated with a limited number of ensemble at large scale, DART's covariance inflation (Anderson, 2009) and localization capabilities are implemented and evaluated. The current NWM data assimilation scheme is compared to preliminary results from the EnKF application for several flooding case studies across the US.

  20. Linking community and national park development: A case from the Dominican Republic

    Treesearch

    John Schelhas; Ruth E. Sherman; Timothy J. Fahey; James P. Lassoie

    2002-01-01

    National parks have complex relationships with local communities that impact both conservation success and community well-being. Integrated conservation arid development projects have been a key approach to managing these relationships, although their effectiveness has been increasingly questioned. Park-people relationships of the Armando Bermudez National Park in the...

  1. Why language matters: insights and challenges in applying a social determination of health approach in a North-South collaborative research program.

    PubMed

    Spiegel, Jerry M; Breilh, Jaime; Yassi, Annalee

    2015-02-27

    Focus on "social determinants of health" provides a welcome alternative to the bio-medical illness paradigm. However, the tendency to concentrate on the influence of "risk factors" related to living and working conditions of individuals, rather than to more broadly examine dynamics of the social processes that affect population health, has triggered critical reaction not only from the Global North but especially from voices the Global South where there is a long history of addressing questions of health equity. In this article, we elaborate on how focusing instead on the language of "social determination of health" has prompted us to attempt to apply a more equity-sensitive approaches to research and related policy and praxis. In this debate, we briefly explore the epistemological and historical roots of epidemiological approaches to health and health equity that have emerged in Latin America to consider its relevance to global discourse. In this region marked by pronounced inequity, context-sensitive concepts such as "collective health" and "critical epidemiology" have been prominent, albeit with limited acknowledgement by the Global North. We illustrate our attempts to apply a social determination approach (and the "4 S" elements of bio-Security, Sovereignty, Solidarity and Sustainability) in five projects within our research collaboration linking researchers and knowledge users in Ecuador and Canada, in diverse settings (health of healthcare workers; food systems; antibiotic resistance; vector borne disease [dengue]; and social circus with street youth). We argue that the language of social determinants lends itself to research that is more reductionist and beckons the development of different skills than would be applied when adopting the language of social determination. We conclude that this language leads to more direct analysis of the systemic factors that drive, promote and reinforce disparities, while at the same time directly considering the emancipatory

  2. Introduction to the U.S. Geological Survey National Water-Quality Assessment (NAWQA) of ground-water quality trends and comparison to other national programs

    USGS Publications Warehouse

    Rosen, Michael R.; Lapham, W.W.

    2008-01-01

    Assessment of temporal trends in national ground-water quality networks are rarely published in scientific journals. This is partly due to the fact that long-term data from these types of networks are uncommon and because many national monitoring networks are not driven by hypotheses that can be easily incorporated into scientific research. The U.S. Geological Survey (USGS) National Water-Quality Assessment Program (NAWQA) since 1991 has to date (2006) concentrated on occurrence of contaminants because sufficient data for trend analysis is only just becoming available. This paper introduces the first set of trend assessments from NAWQA and provides an assessment of the success of the program. On a national scale, nitrate concentrations in ground water have generally increased from 1988 to 2004, but trends in pesticide concentrations are less apparent. Regionally, the studies showed high nitrate concentrations and frequent pesticide detections are linked to agricultural use of fertilizers and pesticides. Most of these areas showed increases in nitrate concentration within the last decade, and these increases are associated with oxic-geochemical conditions and well-drained soils. The current NAWQA plan for collecting data to define trends needs to be constantly reevaluated to determine if the approach fulfills the expected outcome. To assist this evaluation, a comparison of NAWQA to other national ground-water quality programs was undertaken. The design and spatial extent of each national program depend on many factors, including current and long-term budgets, purpose of the program, size of the country, and diversity of aquifer types. Comparison of NAWQA to nine other national programs shows a great diversity in program designs, but indicates that different approaches can achieve similar and equally important goals. Copyright ?? 2008 by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America. All rights reserved.

  3. Cross-Cultural Approaches to Addict Families.

    ERIC Educational Resources Information Center

    Coleman, Sandra B.

    1979-01-01

    From a national survey of family therapy and drug abuse treatment, diverse methods of treating families from varying ethnic/minority backgrounds have been derived in an effort to integrate both family and environmental systems theory--an "ecological" family therapy approach. (Author)

  4. Multiple imputation to evaluate the impact of an assay change in national surveys

    PubMed Central

    Sternberg, Maya

    2017-01-01

    National health surveys, such as the National Health and Nutrition Examination Survey, are used to monitor trends of nutritional biomarkers. These surveys try to maintain the same biomarker assay over time, but there are a variety of reasons why the assay may change. In these cases, it is important to evaluate the potential impact of a change so that any observed fluctuations in concentrations over time are not confounded by changes in the assay. To this end, a subset of stored specimens previously analyzed with the old assay is retested using the new assay. These paired data are used to estimate an adjustment equation, which is then used to ‘adjust’ all the old assay results and convert them into ‘equivalent’ units of the new assay. In this paper, we present a new way of approaching this problem using modern statistical methods designed for missing data. Using simulations, we compare the proposed multiple imputation approach with the adjustment equation approach currently in use. We also compare these approaches using real National Health and Nutrition Examination Survey data for 25-hydroxyvitamin D. PMID:28419523

  5. Error Management Practices Interacting with National and Organizational Culture: The Case of Two State University Departments in Turkey

    ERIC Educational Resources Information Center

    Göktürk, Söheyda; Bozoglu, Oguzhan; Günçavdi, Gizem

    2017-01-01

    Purpose: Elements of national and organizational cultures can contribute much to the success of error management in organizations. Accordingly, this study aims to consider how errors were approached in two state university departments in Turkey in relation to their specific organizational and national cultures. Design/methodology/approach: The…

  6. One health approach to influenza: assessment of critical issues and options.

    PubMed

    Powdrill, Thomas F; Nipp, Terry L; Rinderknecht, Jennifer L

    2010-08-01

    A task force of experts on influenza, public health, and animal health met at the conference One Health Approach to Influenza: Assessment of Critical Issues and Options in Washington, DC, on December 1-2, 2009. These experts discussed the role of the One Health approach in preparing for and responding to an influenza pandemic or other emerging zoonotic disease by using pandemic (H1N1) 2009 as a case study. The meeting was convened by the US Department of Homeland Security National Center for Foreign Animal and Zoonotic Disease Defense, and the National Institute of Allergy and Infectious Diseases/National Institutes of Health Western Regional Center of Excellence for Biodefense and Emerging Infectious Diseases.

  7. 2011 National Drug Control Strategy. Executive Summary

    ERIC Educational Resources Information Center

    Office of National Drug Control Policy, 2011

    2011-01-01

    In May of 2010, President Obama released the Administration's inaugural "National Drug Control Strategy", a comprehensive approach to combat the public health and safety consequences posed by drug use. Now, a year later, the Administration is releasing its update building upon that initial "Strategy". The "Strategy" establishes ambitious goals to…

  8. Creating a National HIV Curriculum.

    PubMed

    Spach, David H; Wood, Brian R; Karpenko, Andrew; Unruh, Kenton T; Kinney, Rebecca G; Roscoe, Clay; Nelson, John

    2016-01-01

    In recent years, the HIV care provider workforce has not kept pace with an expanding HIV epidemic. To effectively address this HIV workforce shortage, a multipronged approach is needed that includes high-quality, easily accessible, up-to-date HIV education for trainees and practicing providers. Toward this objective, the University of Washington, in collaboration with the AIDS Education and Training Center National Coordinating Resource Center, is developing a modular, dynamic curriculum that addresses the entire spectrum of the HIV care continuum. Herein, we outline the general principles, content, organization, and features of this federally funded National HIV Curriculum, which allows for longitudinal, active, self-directed learning, as well as real-time evaluation, tracking, and feedback at the individual and group level. The online curriculum, which is in development, will provide a free, comprehensive, interactive HIV training and resource tool that can support national efforts to expand and strengthen the United States HIV clinical care workforce. Copyright © 2016 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

  9. Use of descriptors of ecosystem functioning for monitoring a national park network: a remote sensing approach.

    PubMed

    Alcaraz-Segura, Domingo; Cabello, Javier; Paruelo, José M; Delibes, Miguel

    2009-01-01

    Baseline assessments and monitoring of protected areas are essential for making management decisions, evaluating the effectiveness of management practices, and tracking the effects of global changes. For these purposes, the analysis of functional attributes of ecosystems (i.e., different aspects of the exchange of matter and energy) has advantages over the traditional use of structural attributes, like a quicker response to disturbances and the fact that they are easily monitored through remote sensing. In this study, we described the spatiotemporal patterns of different aspects of the ecosystem functioning of the Spanish national parks and their response to environmental changes between 1982 and 2006. To do so, we used the NOAA/AVHRR-GIMMS dataset of the Normalized Difference Vegetation Index (NDVI), a linear estimator of the fraction of photosynthetic active radiation intercepted by vegetation, which is the main control of carbon gains. Nearly all parks have significantly changed during the last 25 years: The radiation interception has increased, the contrast between the growing and nongrowing seasons has diminished, and the dates of maximum and minimum interception have advanced. Some parks concentrated more changes than others and the degree of change varied depending on their different environmental conditions, management, and conservation histories. Our approach identified reference conditions and temporal changes for different aspects of ecosystem functioning, which can be used for management purposes of protected areas in response to global changes.

  10. A geospatial approach to identify water quality issues for National Wildlife Refuges in Oregon and Washington

    USGS Publications Warehouse

    Hinck, Jo Ellen; Chojnacki, Kimberly; Finger, Susan E.; Linder, Greg; Kilbride, Kevin

    2011-01-01

    Many National Wildlife Refuges (Refuges) have impaired water quality resulting from historic and current land uses, upstream sources, and aerial pollutant deposition. Competing duties limit the time available for Refuge staff to identify and evaluate potential water quality issues. As a result, water quality–related issues may not be resolved until a problem has already arisen. This study developed a geospatial approach for identifying and prioritizing water quality issues affecting natural resources (including migratory birds and federally listed species) within Refuge boundaries. We assessed the location and status of streams pursuant to the Clean Water Act in relation to individual Refuges in Oregon and Washington, United States. Although twelve Refuges in Oregon (60%) and eight Refuges in Washington (40%) were assessed under the Clean Water Act, only 12% and 3% of total Refuge stream lengths were assessed, respectively. Very few assessed Refuge streams were not designated as impaired (0% in Oregon, 1% in Washington). Despite the low proportions of stream lengths assessed, most Refuges in Oregon (70%) and Washington (65%) are located in watersheds with approved total maximum daily loads. We developed summaries of current water quality issues for individual Refuges and identified large gaps for Refuge-specific water quality data and habitat utilization by sensitive species. We conclude that monitoring is warranted on many Refuges to better characterize water quality under the Clean Water Act.

  11. Qualitative analysis of the risks and practices associated with the spread of African swine fever within the smallholder pig value chains in Uganda.

    PubMed

    Dione, Michel; Ouma, Emily; Opio, Felix; Kawuma, Brian; Pezo, Danilo

    2016-12-01

    A study was undertaken between September 2014 and December 2014 to assess the perceptions of smallholder pig value chain actors of the risks and practices associated with the spread of African swine fever (ASF) disease within the pig value chains. Data was collected from 136 value chain actors and 36 key informants through 17 group discussions and two key informant interview (KII) sessions respectively using Participatory Rural Appraisal (PRA) tools. Results from this study revealed that according to value chain actors and stakeholders, the transporting, slaughtering, and collecting/bulking nodes represent the highest risk, followed by the inputs and services (feeds and drugs) supply nodes. The processing, whole sale and consumption nodes represented the lowest risk. Value chain actors are aware of the disease and its consequences to the pig industry, however biosecurity measures are poorly implemented at all nodes. As for the causes, value chain actors pointed to several factors, such as inadequate knowledge of mechanisms for the spread of the disease, poor enforcement of regulations on disease control, and low capacities of actors to implement biosecurity measures, amongst others. Although traders, butchers and veterinary practitioners accepted that they played an important role in the spread of the virus, they did not perceive themselves as key actors in the control of the disease; instead, they believed that only farmers should adopt biosecurity measures on their farms because they keep the pigs for a longer period. Most of the recommendations given by the value chain actors for controlling and preventing ASF disease were short term, and targeted mainly pig producers. These recommendations included: the establishment of live pig collection centres so that traders and brokers do not have to directly access pig farms, capacity building of value chain actors on application of biosecurity, enactment and enforcement of by-laws on live pig movements and establishment

  12. A network approach to policy framing: A case study of the National Aboriginal and Torres Strait Islander Health Plan.

    PubMed

    Browne, Jennifer; de Leeuw, Evelyne; Gleeson, Deborah; Adams, Karen; Atkinson, Petah; Hayes, Rick

    2017-01-01

    Aboriginal health policy in Australia represents a unique policy subsystem comprising a diverse network of Aboriginal-specific and "mainstream" organisations, often with competing interests. This paper describes the network structure of organisations attempting to influence national Aboriginal health policy and examines how the different subgroups within the network approached the policy discourse. Public submissions made as part of a policy development process for the National Aboriginal and Torres Strait Islander Health Plan were analysed using a novel combination of network analysis and qualitative framing analysis. Other organisational actors in the network in each submission were identified, and relationships between them determined; these were used to generate a network map depicting the ties between actors. A qualitative framing analysis was undertaken, using inductive coding of the policy discourses in the submissions. The frames were overlaid with the network map to identify the relationship between the structure of the network and the way in which organisations framed Aboriginal health problems. Aboriginal organisations were central to the network and strongly connected with each other. The network consisted of several densely connected subgroups, whose central nodes were closely connected to one another. Each subgroup deployed a particular policy frame, with a frame of "system dysfunction" also adopted by all but one subgroup. Analysis of submissions revealed that many of the stakeholders in Aboriginal health policy actors are connected to one another. These connections help to drive the policy discourse. The combination of network and framing analysis illuminates competing interests within a network, and can assist advocacy organisations to identify which network members are most influential. Copyright © 2016 Elsevier Ltd. All rights reserved.

  13. New GIS approaches to wild land mapping in Europe

    Treesearch

    Steffen Fritz; Steve Carver; Linda See

    2000-01-01

    This paper outlines modifications and new approaches to wild land mapping developed specifically for the United Kingdom and European areas. In particular, national level reconnaissance and local level mapping of wild land in the UK and Scotland are presented. A national level study for the UK is undertaken, and a local study focuses on the Cairngorm Mountains in...

  14. Well-informed by national registers? A comparison of national ART registers in Germany, France and the United Kingdom.

    PubMed

    Kadi, Selma; Wiesing, Urban

    2017-12-01

    National registers which document assisted reproductive technology (ART) treatments are important for a range of stakeholders. Their websites and reports are a source of information for ART practitioners, (future) patients and the public. The aim of our study was to compare national ART registers in the three European countries with the largest populations and evaluate whether ART registers currently meet the information needs of the different groups. We compared the publications of national registers in three European countries (the United Kingdom, France and Germany) with diverse regulatory approaches. Our analysis focused on two criteria: data quality and patient orientation. Our findings suggest that the German and French registers' publications fulfil the criteria to a lesser degree than the British register publications, by collecting data that are likely to be less accurate and publishing less information specifically targeted at patients. Differences in the publications and the data collection methods of the three registers impact the opportunities of various stakeholders to access information about ART from their respective national registers.

  15. Advantages of a Unified Earth and Space Science Approach for Geoscience Education: Perspectives from the National Center for Atmospheric Research

    NASA Astrophysics Data System (ADS)

    Johnson, R. M.; Barnes, T.; Bergman, J.; Carbone, L.; Eastburn, T.; Foster, S.; Gardiner, L.; Genyuk, J.; Henderson, S.; Lagrave, M.; Munoz, R.; Russell, R.; Araujo-Pradere, E.; Metcalfe, T.; Mastie, D.; Pennington, P.

    2005-05-01

    The intellectual divisions common among scientists involved in research in specific disciplines are frequently not shared by the broader community of learners. For example, in K-12 education, the Earth sciences and the space sciences have generally been taught in an integrated approach, until opportunities for more advanced courses become available at the higher grade levels in some fortunate school districts. When scientists involved in EPO activities retain a perspective limited to their particular science mission, rather than stepping back to a broader perspective that places the research in a larger context, they risk limiting the usefulness of these activities to a broad cross-section of learners that seek to learn in a contextual framework. The re-integration of Earth and space sciences within NASA's Science Mission Directorate provides an opportunity to more systematically take advantage of the fact that Earth is one of many examples of possible planetary evolution scenarios presented in our solar system and beyond. This development should encourage integration of research across the SMD into a broader context that encourages the development of higher learning skills and a systems thinking approach. At the National Center for Atmospheric Research, the interdisciplinary nature of the research problems we address requires an approach that integrates Earth and space science, and we parallel this in our education and outreach activities, ranging from our exhibits on climate change to our professional development workshops and online courses to our websites and curriculum development efforts. The Windows to the Universe project (http://www.windows.ucar.edu), initiated at the University of Michigan with support from NASA in 1995 and now developed and maintained at the University Corporation for Atmospheric Research, has maintained this integrated approach from its inception with great success - leading to over 6 million users of our English and Spanish language

  16. The Intersection of National Security and Climate Change

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hund, Gretchen; Fankhauser, Jana G.; Kurzrok, Andrew J.

    On June 4, 2014, the Henry M. Jackson Foundation and the Pacific Northwest National Laboratory hosted a groundbreaking symposium in Seattle, Washington, that brought together 36 leaders from federal agencies, state and local governments, NGOs, business, and academia. The participants examined approaches and tools to help decision makers make informed choices about the climate and security risks they face. The following executive summary is based on the day’s discussions and examines the problem of climate change and its impact on national security, the responses to date, and future considerations.

  17. Valuing national effects of digital health investments: an applied method.

    PubMed

    Hagens, Simon; Zelmer, Jennifer; Frazer, Cassandra; Gheorghiu, Bobby; Leaver, Chad

    2015-01-01

    This paper describes an approach which has been applied to value national outcomes of investments by federal, provincial and territorial governments, clinicians and healthcare organizations in digital health. Hypotheses are used to develop a model, which is revised and populated based upon the available evidence. Quantitative national estimates and qualitative findings are produced and validated through structured peer review processes. This methodology has applied in four studies since 2008.

  18. DNA in a bottle-Rapid metabarcoding survey for early alerts of invasive species in ports.

    PubMed

    Borrell, Yaisel J; Miralles, Laura; Do Huu, Hoang; Mohammed-Geba, Khaled; Garcia-Vazquez, Eva

    2017-01-01

    Biota monitoring in ports is increasingly needed for biosecurity reasons and safeguarding marine biodiversity from biological invasion. Present and future international biosecurity directives can be accomplished only if the biota acquired by maritime traffic in ports is controlled. Methodologies for biota inventory are diverse and now rely principally on extensive and labor-intensive sampling along with taxonomic identification by experts. In this study, we employed an extremely simplified environmental DNA (eDNA) sampling methodology from only three 1-L bottles of water per port, followed by metabarcoding (high-throughput sequencing and DNA-based species identification) using 18S rDNA and Cytochrome oxidase I as genetic barcodes. Eight Bay of Biscay ports with available inventory of fouling invertebrates were employed as a case study. Despite minimal sampling efforts, three invasive invertebrates were detected: the barnacle Austrominius modestus, the tubeworm Ficopomatus enigmaticus and the polychaete Polydora triglanda. The same species have been previously found from visual and DNA barcoding (genetic identification of individuals) surveys in the same ports. The current costs of visual surveys, conventional DNA barcoding and this simplified metabarcoding protocol were compared. The results encourage the use of metabarcoding for early biosecurity alerts.

  19. DNA in a bottle—Rapid metabarcoding survey for early alerts of invasive species in ports

    PubMed Central

    Miralles, Laura; Do Huu, Hoang; Mohammed-Geba, Khaled; Garcia-Vazquez, Eva

    2017-01-01

    Biota monitoring in ports is increasingly needed for biosecurity reasons and safeguarding marine biodiversity from biological invasion. Present and future international biosecurity directives can be accomplished only if the biota acquired by maritime traffic in ports is controlled. Methodologies for biota inventory are diverse and now rely principally on extensive and labor-intensive sampling along with taxonomic identification by experts. In this study, we employed an extremely simplified environmental DNA (eDNA) sampling methodology from only three 1-L bottles of water per port, followed by metabarcoding (high-throughput sequencing and DNA-based species identification) using 18S rDNA and Cytochrome oxidase I as genetic barcodes. Eight Bay of Biscay ports with available inventory of fouling invertebrates were employed as a case study. Despite minimal sampling efforts, three invasive invertebrates were detected: the barnacle Austrominius modestus, the tubeworm Ficopomatus enigmaticus and the polychaete Polydora triglanda. The same species have been previously found from visual and DNA barcoding (genetic identification of individuals) surveys in the same ports. The current costs of visual surveys, conventional DNA barcoding and this simplified metabarcoding protocol were compared. The results encourage the use of metabarcoding for early biosecurity alerts. PMID:28873426

  20. Surety of the nation`s critical infrastructures: The challenge restructuring poses to the telecommunications sector

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cox, R.; Drennen, T.E.; Gilliom, L.

    1998-04-01

    The telecommunications sector plays a pivotal role in the system of increasingly connected and interdependent networks that make up national infrastructure. An assessment of the probable structure and function of the bit-moving industry in the twenty-first century must include issues associated with the surety of telecommunications. The term surety, as used here, means confidence in the acceptable behavior of a system in both intended and unintended circumstances. This paper outlines various engineering approaches to surety in systems, generally, and in the telecommunications infrastructure, specifically. It uses the experience and expectations of the telecommunications system of the US as an examplemore » of the global challenges. The paper examines the principal factors underlying the change to more distributed systems in this sector, assesses surety issues associated with these changes, and suggests several possible strategies for mitigation. It also studies the ramifications of what could happen if this sector became a target for those seeking to compromise a nation`s security and economic well being. Experts in this area generally agree that the U. S. telecommunications sector will eventually respond in a way that meets market demands for surety. Questions remain open, however, about confidence in the telecommunications sector and the nation`s infrastructure during unintended circumstances--such as those posed by information warfare or by cascading software failures. Resolution of these questions is complicated by the lack of clear accountability of the private and the public sectors for the surety of telecommunications.« less