INL Director Explains How the National Labs Are Assisting With Japan's Nuclear Crisis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grossenbacher, John

2011-04-14

Idaho National Laboratory's Director John Grossenbacher discusses the types of nuclear expertise and capabilities that exist within the U.S. Department of Energy's national labs to assist with the Japan nuclear crisis. He also explains how the labs will provide long-term research that will uncover lessons learned from the Fukushima nuclear plants. For more information about INL's nuclear energy research, visit http://www.facebook.com/idahonationallaboratory.

INL Director Explains How the National Labs Are Assisting With Japan's Nuclear Crisis

ScienceCinema

Grossenbacher, John

2018-02-06

Idaho National Laboratory's Director John Grossenbacher discusses the types of nuclear expertise and capabilities that exist within the U.S. Department of Energy's national labs to assist with the Japan nuclear crisis. He also explains how the labs will provide long-term research that will uncover lessons learned from the Fukushima nuclear plants. For more information about INL's nuclear energy research, visit http://www.facebook.com/idahonationallaboratory.

National Labs and Nuclear Emergency Response

NASA Astrophysics Data System (ADS)

Budil, Kimberly

2015-04-01

The DOE national laboratories, and in particular the three NNSA national security laboratories, have long supported a broad suite of national nuclear security missions for the U.S. government. The capabilities, infrastructure and base of expertise developed to support the U.S. nuclear weapons stockpile have been applied to such challenges as stemming nuclear proliferation, understanding the nuclear capabilities of adversaries, and assessing and countering nuclear threats including essential support to nuclear emergency response. This talk will discuss the programs that are underway at the laboratories and the essential role that science and technology plays therein. Nuclear scientists provide expertise, fundamental understanding of nuclear materials, processes and signatures, and tools and technologies to aid in the identification and mitigation of nuclear threats as well as consequence management. This talk will also discuss the importance of direct engagement with the response community, which helps to shape research priorities and to enable development of useful tools and techniques for responders working in the field. National Labs and Nuclear Emergency Response.

Data from Dr. Douglas Matson's aerodynamic levitator being analy

NASA Image and Video Library

2017-10-20

Sangho Jeon (Tufts University), Thomas Leitner (Graz University of Technology), and Trudy Allen analyze data from Dr. Douglas Matson's aerodynamic levitator in support of his MaterialsLab experiments.

Podcast: Scientific Integrity and Lab Fraud

EPA Pesticide Factsheets

Nov 25, 2015. Dr. Bruce Woods, a chemist in the Electronic Crimes Division within the OIG’s Office of Investigations discusses his recent webinar for the Association of Public Health Laboratories on lab fraud.

DOE EiR at Oakridge National Lab 2008/09

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bauer, Michael

2012-11-30

This project placed an experienced technology entrepreneur at Oak Ridge National Lab, one of DOE's premier laboratories undertaking cutting edge research in a variety of fields, including energy technologies. With the goal of accelerating the commercialization of advanced energy technologies, the task was to review available technologies at the lab and identify those that qualify for licensing and commercialization by a private startup company, backed by private venture capital. During the project, more than 1,500 inventions filed at the lab were reviewed over a 1 year period; a successively smaller number was selected for more detailed review, ultimately resulting inmore » five, and then 1 technology, being reviewed for immediate commercialization. The chosen technology, consisting in computational chemistry based approached to optimization of enzymes, was tested in lab experiments, paid for by funds raised by ORNL for the purpose of proving out the effectiveness of the technology and readiness for commercialization. The experiments proved out that the technology worked however it's performance proved not yet mature enough to qualify for private venture capital funded commercialization in a high tech startup. As a consequence, the project did not result in a new startup company being formed, as originally intended.« less

Advanced LabVIEW Labs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Eric D.

1999-06-17

In the world of computer-based data acquisition and control, the graphical interface program LabVIEW from National Instruments is so ubiquitous that in many ways it has almost become the laboratory standard. To date, there have been approximately fifteen books concerning LabVIEW, but Professor Essick's treatise takes on a completely different tack than all of the previous discussions. In the more standard treatments of the ways and wherefores of LabVIEW such as LabVIEW Graphical Programming: Practical Applications in Instrumentation and Control by Gary W. Johnson (McGraw Hill, NY 1997), the emphasis has been instructing the reader how to program LabVIEW tomore » create a Virtual Instrument (VI) on the computer for interfacing to a particular instruments. LabVIEW is written in G a graphical programming language developed by National Instruments. In the past the emphasis has been on training the experimenter to learn G . Without going into details here, G incorporates the usual loops, arithmetic expressions, etc., found in many programming languages, but in an icon (graphical) environment. The net result being that LabVIEW contains all of the standard methods needed for interfacing to instruments, data acquisition, data analysis, graphics, and also methodology to incorporate programs written in other languages into LabVIEW. Historically, according to Professor Essick, he developed a series of experiments for an upper division laboratory course for computer-based instrumentation. His observation was that while many students had the necessary background in computer programming languages, there were students who had virtually no concept about writing a computer program let alone a computer- based interfacing program. Thus the beginnings of a concept for not only teaching computer- based instrumentation techniques, but aiso a method for the beginner to experience writing a com- puter program. Professor Essick saw LabVIEW as the perfect environment in which to teach

Advanced LabVIEW Labs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, Eric D.

1999-06-17

In the world of computer-based data acquisition and control, the graphical interface program LabVIEW from National Instruments is so ubiquitous that in many ways it has almost become the laboratory standard. To date, there have been approximately fifteen books concerning LabVIEW, but Professor Essick's treatise takes on a completely different tack than all of the previous discussions. In the more standard treatments of the ways and wherefores of LabVIEW such as LabVIEW Graphical Programming: Practical Applications in Instrumentation and Control by Gary W. Johnson (McGraw Hill, NY 1997), the emphasis has been instructing the reader how to program LabVIEW tomore » create a Virtual Instrument (VI) on the computer for interfacing to a particular instruments. LabVIEW is written in "G" a graphical programming language developed by National Instruments. In the past the emphasis has been on training the experimenter to learn "G". Without going into details here, "G" incorporates the usual loops, arithmetic expressions, etc., found in many programming languages, but in an icon (graphical) environment. The net result being that LabVIEW contains all of the standard methods needed for interfacing to instruments, data acquisition, data analysis, graphics, and also methodology to incorporate programs written in other languages into LabVIEW. Historically, according to Professor Essick, he developed a series of experiments for an upper division laboratory course for computer-based instrumentation. His observation was that while many students had the necessary background in computer programming languages, there were students who had virtually no concept about writing a computer program let alone a computer- based interfacing program. Thus the beginnings of a concept for not only teaching computer- based instrumentation techniques, but aiso a method for the beginner to experience writing a com- puter program. Professor Essick saw LabVIEW as the "perfect environment in which to

Institutional profile: the national Swedish academic drug discovery & development platform at SciLifeLab

PubMed Central

Arvidsson, Per I; Sandberg, Kristian; Sakariassen, Kjell S

2017-01-01

The Science for Life Laboratory Drug Discovery and Development Platform (SciLifeLab DDD) was established in Stockholm and Uppsala, Sweden, in 2014. It is one of ten platforms of the Swedish national SciLifeLab which support projects run by Swedish academic researchers with large-scale technologies for molecular biosciences with a focus on health and environment. SciLifeLab was created by the coordinated effort of four universities in Stockholm and Uppsala: Stockholm University, Karolinska Institutet, KTH Royal Institute of Technology and Uppsala University, and has recently expanded to other Swedish university locations. The primary goal of the SciLifeLab DDD is to support selected academic discovery and development research projects with tools and resources to discover novel lead therapeutics, either molecules or human antibodies. Intellectual property developed with the help of SciLifeLab DDD is wholly owned by the academic research group. The bulk of SciLifeLab DDD's research and service activities are funded from the Swedish state, with only consumables paid by the academic research group through individual grants. PMID:28670468

Institutional profile: the national Swedish academic drug discovery & development platform at SciLifeLab.

PubMed

Arvidsson, Per I; Sandberg, Kristian; Sakariassen, Kjell S

2017-06-01

The Science for Life Laboratory Drug Discovery and Development Platform (SciLifeLab DDD) was established in Stockholm and Uppsala, Sweden, in 2014. It is one of ten platforms of the Swedish national SciLifeLab which support projects run by Swedish academic researchers with large-scale technologies for molecular biosciences with a focus on health and environment. SciLifeLab was created by the coordinated effort of four universities in Stockholm and Uppsala: Stockholm University, Karolinska Institutet, KTH Royal Institute of Technology and Uppsala University, and has recently expanded to other Swedish university locations. The primary goal of the SciLifeLab DDD is to support selected academic discovery and development research projects with tools and resources to discover novel lead therapeutics, either molecules or human antibodies. Intellectual property developed with the help of SciLifeLab DDD is wholly owned by the academic research group. The bulk of SciLifeLab DDD's research and service activities are funded from the Swedish state, with only consumables paid by the academic research group through individual grants.

Dr. Wernher Von Braun

NASA Technical Reports Server (NTRS)

1999-01-01

Dr. Thomas Paine, Deputy Administrator of the National Aeronautics and Space Administration, examines an ordinary man's shoe outfitted for use in the Saturn I workshop. Pictured from the left in the Saturn I workshop mockup are William Brooksbank, propulsion and vehicle engineering laboratory; Dr. Paine; Dr. Wernher Von Braun, Marshall Center director; Colonel Clare F. Farley, Executive Officer in the Office Of The Administrator; and Charles J. Donlan, Deputy Associate Administrator for Manned Space Flight, Technical. the shoe Dr. Paine is holding has a unique fastener built into the sole to allow an astronaut to move about on the workshop floor and to remain in one position if he desires.

Frederick National Lab Collaborates with Moffitt Cancer Center on HPV and Oral Cancer | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Lab and Moffitt Cancer Center have established a collaboration to research antibody responses against the human papillomavirus (HPV) in males following administration of the Gardasil vaccine. The vaccine prevents HPV infections

Frederick National Lab Supports Clinical Trials for Vaccine Against Mosquito-borne Chikungunya | Frederick National Laboratory for Cancer Research

Cancer.gov

An experimental vaccine for mosquito-borne chikungunya is being tested at sites in the Caribbean as part of a phase II clinical trial being managed by the Frederick National Lab. No vaccine or treatment currently exists for the viral disease, which c

Hundreds of Area Residents Visit the National Lab Booth at the Annual In The Street Festival | Poster

Cancer.gov

Light-up yo-yos, brightly colored portion plates, and a fast spinner game lured hundreds of area residents to the Frederick National Lab booth at this year’s In The Street festival, where they also heard a message from the lab: Stay healthy through healthy habits.

IBBR and Frederick National Lab Collaborate to Study Vaccine-Boosting Compounds | FNLCR Staging

Cancer.gov

The Frederick National Lab and the University of Maryland’s Institute for Bioscience and Biotechnology Research (IBBR) will work under a formal collaboration to evaluate the effectiveness of new compounds that might be used to enhance the immune re

Role of national labs in energy and environmental R & D: An industrial perspective

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vaz, N.

1995-12-31

The perceived role of national laboratories in energy and environmental research and development is examined from an industrial perspective. A series of tables are used to summarize issues primarily related to the automotive industry. Impacts of policy on energy, environment, society, and international competition are outlined. Advances and further needs in automotive efficiency and pollution control, and research roles for national labs and industry are also summarized. 6 tabs.

Dr. Wernher Von Braun Memorial Dinner

NASA Image and Video Library

2017-10-26

The annual Dr. Wernher Von Braun Memorial Dinner was held at the U.S. Space and Rocket Center's Davidson Center on October 26, 2017 with Keynote speaker General John Hyten, Commander of U.S. Strategic Command. Emcee was Mark Larson of Mark Larson Media Services, Inc. Dr. Wernher Von Braun Memorial Scholarships were presented to 8 college students by the National Space Club. Educator of the Year was awarded to Tammy Thorpe; Community Service award was presented to Huntsville, Al. Mayor Tommy Battle. The Communications Award was presented to retired astronaut Dr. Mike Massimino. The Distinguished Science Award was presented to Dr. Martin Weisskopf. The Astronautics Engineer Award was presented to Douglas R. Cooke. The Dr. Wernher Von Braun Space Flight Trophy was presented to Robert Lightfoot.

Frederick National Lab Collaborates with Moffitt Cancer Center on HPV and Oral Cancer | FNLCR Staging

Cancer.gov

The Frederick National Lab and Moffitt Cancer Center have established a collaboration to research antibody responses against the human papillomavirus (HPV) in males following administration of the Gardasil vaccine. The vaccine prevents HPV infections

Dr. Stefan Ambs: Increasing Diversity in Cancer Research: One Lab at a Time

Cancer.gov

As part of the series “Increasing Diversity in Cancer Research,” CRCHD interviewed Dr. Stefan Ambs, an investigator at NCI’s Center for Cancer Research, who is using novel approaches to discover gene differences in the tumors of African American patients.

Dr. Dinah Singer: Increasing Diversity in Cancer Research: One Lab at a Time

Cancer.gov

As part of the series “Increasing Diversity in Cancer Research,” CRCHD spoke with Dr. Dinah Singer, Director of NCI’s Division of Cancer Biology, about training and mentorship, and the role it plays in attracting and retaining students and investigators underrepresented in cancer research.

National Lab Science Day | News

Science.gov Websites

Laboratory news From lab leadership Submit content - login required Provide feedback Subscribe to our officer at Fermilab, guided Secretary Moniz and members of the U.S. Senate and House on virtual tours of virtual tour Particle detector tours Collisions in 3-D DOE facilities Dark matter and dark energy Particle

Dr. Jason Dworkin, Project Scientist

NASA Image and Video Library

2017-12-08

Dr. Jason Dworkin, Project Scientist for NASA's OSIRIS-Rex mission is seen hear sealing a glass test tube with a sample of Allende meteorite dust which is 4.567 BILLION years old. Jason is the Chief of NASA Goddard's Astrochemistry Lab. Read more about the mission here: www.nasa.gov/mission_pages/osiris-rex Credit: NASA/Goddard/Debbie Mccallum NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Future{at}Labs.Prosperity Game{trademark}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Beck, D.F.; Boyack, K.W.; Berman, M.

Prosperity Games{trademark} are an outgrowth and adaptation of move/countermove and seminar War Games, Prosperity Games{trademark} are simulations that explore complex issues in a variety of areas including economics, politics, sociology, environment, education, and research. These issues can be examined from a variety of perspectives ranging from global, macroeconomic and geopolitical viewpoint down to the details of customer/supplier/market interactions specific industries. All Prosperity Games{trademark} are unique in that both the game format and the player contributions vary from game to game. This report documents the Future{at}Labs.Prosperity Game{trademark} conducted under the sponsorship of the Industry Advisory Boards of the national labs, themore » national labs, Lockheed Martin Corporation, and the University of California. Players were drawn from all stakeholders involved including government, industry, labs, and academia. The primary objectives of this game were to: (1) explore ways to optimize the role of the multidisciplinary labs in serving national missions and needs; (2) explore ways to increase collaboration and partnerships among government, laboratories, universities, and industry; and (3) create a network of partnership champions to promote findings and policy options. The deliberations and recommendations of these players provided valuable insights as to the views of this diverse group of decision makers concerning the future of the labs.« less

"Did You Say 50% of My Grade?"--Teaching Introductory Physics to Non-Science Majors through a Haunted Physics Lab

ERIC Educational Resources Information Center

Donaldson, Nancy

2010-01-01

Several years ago I attended an AAPT Haunted Physics Workshop taught by Dr. Tom Zepf from Creighton University. Dr. Zepf's highly successful Haunted Physics Lab at Creighton was put on every October by his physics majors. I found the concept of exhibiting physics projects in a "fun" way to students, faculty, and the public very exciting, so an…

Dr. Hugh L. Dryden - portrait

NASA Technical Reports Server (NTRS)

1959-01-01

Dr. Hugh Latimer Dryden, had many titles after his name in his lifetime. In 1949 he became the director of the National Advisory Committee for Aeronautics (NACA). Dr. Dryden received many accolades and awards both during his life and after his death, but the greatest and most appropriate honor came on March 26, 1976, when NASA renamed the NASA Flight Research Center as the NASA Hugh L. Dryden Flight Research Center. At the dedication ceremony NASA Administrator James C. Fletcher stated: 'in 1924, when the fastest racing planes did well to fly at 280 m.p.h., Dryden was already probing the transonic range of . . . flight. Later in the 1920s, he sought to develop methods of accurately measuring . . . turbulence in wind tunnels. In 1938 he was the first American to deliver the Wright Brothers lecture. His 'Turbulence and the Boundary Layer' became a classic summary on the subject. It is most fitting that this Flight Research Center, with its unique and highly specialized capability for solving aerospace problems, should memorialize the genius of Hugh Dryden.' Dr. Dryden was initially an aerodynamicist with the National Bureau of Standards. He did important early work in high-speed aerodynamics. In 1947 he became the director of aeronautical research for the NACA (a predecessor of the National Aeronautics and Space Administration). Two years later, he became NACA's director, a position he held until 1958 when he became deputy administrator of NASA.

Vikrant Sahasrabuddhe, MBBS, MPH, DrPH | Division of Cancer Prevention

Cancer.gov

Dr. Vikrant Sahasrabuddhe is Program Director in the Division of Cancer Prevention at the National Cancer Institute overseeing clinical trials focused on prevention of cervical cancer and other human papillomavirus (HPV)-related cancers. Dr. |

Final Report on A. R. A. P.’s Model for the Atmospheric Marine Environment

DTIC Science & Technology

1982-01-01

Around Airports," NASA CR-2752, prepared by A.R.A.P. for Marshall Space Center. 25. Brost , R.A. and Wyngaard, N.C., 1978: "A Model Study of the...FRANCE DR. R. A. BROST NCAR P.O. BOX 3000 BOULDER, CO 80307 JOHNS HOPKINS UNIV. APPLIED PHYSICS LAB R.E. GIBSON LIBRARY JOHNS HOPKINS ROAD...RESEARCH LABS BOULDER, CO 80303 DR. GEORGE L. HELLOR GEOPHYSICAL FLUID DYNAMICS LAE PRINCETON, NJ 08540 DR. TETSUJI YAMADA LOS ALAMOS NATIONAL LAB

In Defense of the National Labs and Big-Budget Science

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goodwin, J R

2008-07-29

The purpose of this paper is to present the unofficial and unsanctioned opinions of a Visiting Scientist at Lawrence Livermore National Laboratory on the values of LLNL and the other National Labs. The basic founding value and goal of the National Labs is big-budget scientific research, along with smaller-budget scientific research that cannot easily be done elsewhere. The most important example in the latter category is classified defense-related research. The historical guiding light here is the Manhattan Project. This endeavor was unique in human history, and might remain so. The scientific expertise and wealth of an entire nation was tappedmore » in a project that was huge beyond reckoning, with no advance guarantee of success. It was in many respects a clash of scientific titans, with a large supporting cast, collaborating toward a single well-defined goal. Never had scientists received so much respect, so much money, and so much intellectual freedom to pursue scientific progress. And never was the gap between theory and implementation so rapidly narrowed, with results that changed the world, completely. Enormous resources are spent at the national or international level on large-scale scientific projects. LLNL has the most powerful computer in the world, Blue Gene/L. (Oops, Los Alamos just seized the title with Roadrunner; such titles regularly change hands.) LLNL also has the largest laser in the world, the National Ignition Facility (NIF). Lawrence Berkeley National Lab (LBNL) has the most powerful microscope in the world. Not only is it beyond the resources of most large corporations to make such expenditures, but the risk exceeds the possible rewards for those corporations that could. Nor can most small countries afford to finance large scientific projects, and not even the richest can afford largess, especially if Congress is under major budget pressure. Some big-budget research efforts are funded by international consortiums, such as the Large Hadron

Dr. Igor Sikorsky Visits the Lewis Flight Propulsion Laboratory

NASA Image and Video Library

1951-06-21

Dr. Igor Sikorsky, fourth from the left, visits the National Advisory Committee for Aeronautics (NACA) Lewis Flight Propulsion Laboratory in Cleveland, Ohio. The legendary Russian-born aviation pioneer visited NACA Lewis several times during the 1940s and 1950s. In 1946 Sikorsky arrived at Lewis for the 1946 National Air Races, which included demonstrations by five of his helicopters. NACA flight mechanic Joseph Sikosky personally escorted Sikorsky during the visit. Sikorsky frequently addressed local professional organizations, such as the American Society of Mechanical Engineers, during his visits. Sikorsky built and flew the first multi-engine aircraft as a youth in Russia. In his mid-20s Sikorsky designed and oversaw the manufacturing of 75 four-engine bombers. During the Bolshevik Revolution he fled to New York City where he worked jobs outside of aviation. In 1923 Sikorsky obtained funding to build a twin-engine water aircraft. This aircraft was the first US twin-engine flying machine and a world-wide success. In 1939 Sikorsky designed the first successful US helicopter. He then put all of his efforts into helicopters, and built some of the most successful helicopters in use today. Sikorsky passed away in 1972. From left to right: unknown; John Collins, Chief of the Engine Performance and Materials Division; Abe Silverstein, Chief of Research; Sikorsky; lab Director Ray Sharp; and Executive Officer Robert Sessions.

Innovation - A view from the Lab

USDA-ARS?s Scientific Manuscript database

The USDA Ag Lab in Peoria helps bridge the gap between agricultural producers and commercial manufacturers. In 2015, the Ag Lab, officially known as the Agricultural Research Service (ARS) National Center for Agricultural Utilization Research (NCAUR), is celebrating 75 years of research in Peoria. T...

Berkeley Lab - Lawrence Berkeley National Laboratory

Science.gov Websites

nanoparticles that could make solar panels more efficient by converting light usually missed by solar cells into of Methane's Increasing Greenhouse Effect A Berkeley Lab research team tracked a rise in the warming effect of methane - one of the most important greenhouse gases for the Earth's atmosphere - over a 10

[Dr. Joseph Chazanowicz (1844-1919) and the National Library in Jerusalem].

PubMed

Ohry, Avi

2014-01-01

Dr. Joseph Chazanowicz (1844-1919), was a Russian physician, and founder of the Jewish National Library in JerusaLem. After completing his studies at the Jewish school and at the gymnasium of Grodno, Chazanowicz went to Königsberg, Germany to study medicine and finished his studies in 1872. Returning to Russia, he began to practice at Byelostok's Jewish hospital. Chazanowicz founded the Hovevei Ziyyon ["Lovers of Zion"] society and also the Linat Ha-Zedek ("Hospice for the Poor")--caring for the poor. In 1890 he visited Palestine and conceived the idea of founding a library in Jerusalem, together with the B'nai B'rith organization. In 1896 he sent his large collection of books, amounting to nearly 10,000 volumes, to Jerusalem as the beginning of the Abarbanel library. The enlargement of this library and the collection of funds to erect a special building for it became the life-work of Chazanowicz.

[From the asylums to the community: the reform process of National Colony "Dr. Manuel A. Montes de Oca"].

PubMed

Rossetto, Jorge

2009-01-01

Since 2004, a profound transformation of the asylum care model, characterized by overcrowding, lack of discharge and absence of rehabilitation programs, and social reinsertion, has been developed at National Colony "Dr. Manuel A. Montes de Oca". During this period, a plan that contemplates several programs and projects aimed at restoring the rights of institutionalized people with mental disabilities and promoting opportunities for social inclusion has been implemented.

1. View of three detection radar (DR) antennas. DR 1 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

1. View of three detection radar (DR) antennas. DR 1 (structure no. 735) on left, DR 2 (structure no. 736) in center, and DR 3 (structure no. 737) looking north 30 degrees west, with tracking radar (large radome) and satcom (satellite communication) system in small radome in view between DR 2 and DR 3 antennae. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

EPICS Channel Access Server for LabVIEW

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhukov, Alexander P.

It can be challenging to interface National Instruments LabVIEW (http://www.ni.com/labview/) with EPICS (http://www.aps.anl.gov/epics/). Such interface is required when an instrument control program was developed in LabVIEW but it also has to be part of global control system. This is frequently useful in big accelerator facilities. The Channel Access Server is written in LabVIEW, so it works on any hardware/software platform where LabVIEW is available. It provides full server functionality, so any EPICS client can communicate with it.

Interview with Dr Ghassan K Abou-Alfa.

PubMed

Abou-Alfa, G K

2016-11-01

Ghassan K Abou-Alfa joined the Gastrointestinal Oncology Service at Memorial Sloan-Kettering Cancer Center and Weill Cornell Medical College in New York back in 2001. Dr Abou-Alfa specializes in the treatment of gastrointestinal malignancies. Dr Abou-Alfa received his medical degree from the American University of Beirut, Lebanon, and completed his post-doctoral training at Yale University School of Medicine. His research is dedicated to finding novel therapies and improving the effectiveness of the current therapies for hepatocellular carcinoma, cholangiocarcinoma and gallbladder cancer, while continuing to understand the basic mechanisms of the diseases and its therapy. Dr Abou-Alfa has invested several years in helping develop multi-tyrosine kinases and more immune-modulator therapies. Dr Abou-Alfa has many publications in the field. He led on many occasions international teams of investigators. Dr Abou-Alfa serves as the chair of the National Cancer Institute (NCI) Task Force for Hepatobiliary Cancers and the chair of the AIDS Malignancy Consortium (AMC) Non-AIDS Defining Malignancies (NADC) Liver/GI Task Force. Dr Abou-Alfa also co-chairs the hepatobiliary cancers subgroup of the Alliance cooperative group, and is a cadre member of both the gastrointestinal cancers and pharmacogenomics and population pharmacology committees. Dr Abou-Alfa who has lectured worldwide on the subject on gastrointestinal malignancies, is also a strong advocate for raising awareness and support for improving the outcome of patients with this disease, and enhancing oncologic education worldwide.

Dissemination of information about the technologies of the Vision Research Lab through the World Wide Web

NASA Technical Reports Server (NTRS)

Dorais, Christopher M.

2004-01-01

The Vision Research Lab at NASA John Glenn Research Center is headed by Dr. Rafat Ansari. Dr. Ansari and other researchers have developed technologies that primarily use laser and fiber optics to non-invasively detect different ailments and diseases of the eye. One of my goals as a LERCIP intern and ACCESS scholar for the 2004 summer is to inform other NASA employees, researchers and the general public about these technologies through the development of a website. The website incorporates the theme that the eye is a window to the body. Thus by investigating the processes of the eye, we can better understand and diagnosis different ailments and diseases. These ailments occur in not only earth bound humans, but astronauts as well as a result of exposure to elevated levels of radiation and microgravity conditions. Thus the technologies being developed at the Vision Research Lab are invaluable to humans on Earth in addition to those astronauts in space. One of my first goals was to research the technologies being developed at the lab. The first several days were spent immersing myself in the various articles, journals and reports about the theories behind Dynamic Light Scattering, Laser Doppler Flowmetry, Autofluoresence, Raman Spectroscopy, Polarimetry and Oximetry. Interviews with the other researchers proved invaluable to help understand these theories as well gain hands on experience with the devices being developed using these technologies. The rest of the Vision Research Team and I sat down and discussed how the overall website should be presented. Combining this information with the knowledge of the theories and applications of the hardware being developed, I worked out different ideas to present this information. I quickly learned Paint Shop Pro 8 and FrontPage 2002, as well as using online tutorials and other resources to help design an effective website. The Vision Research Lab website incorporates the anatomy and physiology of the eye, different diseases

Reflections on Three Corporate Research Labs: Bell Labs, HP Labs, Agilent Labs

NASA Astrophysics Data System (ADS)

Hollenhorst, James

2008-03-01

This will be a personal reflection on corporate life and physics-based research in three industrial research labs over three decades, Bell Labs during the 1980's, HP Labs during the 1990's, and Agilent Labs during the 2000's. These were times of great change in all three companies. I'll point out some of the similarities and differences in corporate cultures and how this impacted the research and development activities. Along the way I'll mention some of the great products that resulted from physics-based R&D.

Jefferson Lab Virtual Tour

ScienceCinema

None

2018-01-16

Take a virtual tour of the campus of Thomas Jefferson National Accelerator Facility. You can see inside our two accelerators, three experimental areas, accelerator component fabrication and testing areas, high-performance computing areas and laser labs.

Designing virtual science labs for the Islamic Academy of Delaware

NASA Astrophysics Data System (ADS)

AlZahrani, Nada Saeed

Science education is a basic part of the curriculum in modern day classrooms. Instructional approaches to science education can take many forms but hands-on application of theory via science laboratory activities for the learner is common. Not all schools have the resources to provide the laboratory environment necessary for hands-on application of science theory. Some settings rely on technology to provide a virtual laboratory experience instead. The Islamic Academy of Delaware (IAD), a typical community-based organization, was formed to support and meet the essential needs of the Muslim community of Delaware. IAD provides science education as part of the overall curriculum, but cannot provide laboratory activities as part of the science program. Virtual science labs may be a successful model for students at IAD. This study was conducted to investigate the potential of implementing virtual science labs at IAD and to develop an implementation plan for integrating the virtual labs. The literature has shown us that the lab experience is a valuable part of the science curriculum (NBPTS, 2013, Wolf, 2010, National Research Council, 1997 & 2012). The National Research Council (2012) stressed the inclusion of laboratory investigations in the science curriculum. The literature also supports the use of virtual labs as an effective substitute for classroom labs (Babateen, 2011; National Science Teachers Association, 2008). Pyatt and Simms (2011) found evidence that virtual labs were as good, if not better than physical lab experiences in some respects. Although not identical in experience to a live lab, the virtual lab has been shown to provide the student with an effective laboratory experience in situations where the live lab is not possible. The results of the IAD teacher interviews indicate that the teachers are well-prepared for, and supportive of, the implementation of virtual labs to improve the science education curriculum. The investigator believes that with the

[United Nations world population prize to Dr. Halfdan Mahler. Acceptance speech].

PubMed

Mahler, H

1995-06-01

The professional achievements of Halfdan Mahler, for which he was awarded the 1995 UN World Population Prize, are summarized, and Dr. Mahler's acceptance speech is presented. Dr. Mahler worked for reproductive health and sustainable development during his six years as secretary general of the IPPF. Under his leadership, the IPPF established world standards for family planning and reproductive health. Dr. Mahler also guided creation and implementation of the long-term IPPF strategic plan, Vision 2000. During his tenure as director general of the World Health Organization from 1973 to 1988, he established the special program of education, development, and training for research in human reproduction. Dr. Mahler's acceptance speech sketched a world of the future in which women control their reproductive lives and enjoy equality with men in work and at home, where adolescents understand and control their sexuality, where all children are desired and cared for, and where hard work brings success even in the poorest population sectors. The challenges of achieving this vision are enormous. The world's population will have doubled to 10 billion, and tensions and inequities will persist. But if the vision is not fulfilled, the present population will triple to 15 billion and competition for every kind of resource will be intolerable. In order to succeed, the rights to free and informed reproductive decision making must be guaranteed for every couple. Harmful practices that violate the right to autonomous reproductive decision making, such as early marriage or female genital mutilation, must be eliminated. Governments must commit themselves to educating and providing resources to women so that they can exercise their rights. Family planning services must be extended to the poor and marginal population sectors that still are denied access, and to adolescents who are at risk of unwanted pregnancy and disease.

[Dr Stockmann and Dr Snow--two heroes of public health].

PubMed

Nylenna, Magne

2003-12-23

Dr Thomas Stockmann, the main character of An enemy of the people by Henrik Ibsen (1828-1906), has been described as a hero of public health. In spite of his idealism and high principles, he was, however, not able to do anything about the contaminated water supply of the baths in the town where he lived. Important differences may be noticed if we compare the fictional Dr Stockmann with Dr John Snow (1813-58), a real hero of public health famous for his handling of a cholera epidemic in London in 1854. While Dr Snow carried out extensive investigations of the relation between water supply and illness and still was humble when presenting his findings, the fictional Dr Stockmann took only one sample of water for examination and was bombastic in his conclusion. And while Dr Snow had a simple suggestion for solving the problem, Dr Stockmann seemed more eager to dramatize the situation. Scientific documentation and a practical attitude to problem solving continue to be important in order to achieve results in the field of public health.

DR-Integrator: a new analytic tool for integrating DNA copy number and gene expression data.

PubMed

Salari, Keyan; Tibshirani, Robert; Pollack, Jonathan R

2010-02-01

DNA copy number alterations (CNA) frequently underlie gene expression changes by increasing or decreasing gene dosage. However, only a subset of genes with altered dosage exhibit concordant changes in gene expression. This subset is likely to be enriched for oncogenes and tumor suppressor genes, and can be identified by integrating these two layers of genome-scale data. We introduce DNA/RNA-Integrator (DR-Integrator), a statistical software tool to perform integrative analyses on paired DNA copy number and gene expression data. DR-Integrator identifies genes with significant correlations between DNA copy number and gene expression, and implements a supervised analysis that captures genes with significant alterations in both DNA copy number and gene expression between two sample classes. DR-Integrator is freely available for non-commercial use from the Pollack Lab at http://pollacklab.stanford.edu/ and can be downloaded as a plug-in application to Microsoft Excel and as a package for the R statistical computing environment. The R package is available under the name 'DRI' at http://cran.r-project.org/. An example analysis using DR-Integrator is included as supplemental material. Supplementary data are available at Bioinformatics online.

KENNEDY SPACE CENTER, FLA. - Officials of the NASA-Kennedy Space Center and the state of Florida pose for a group portrait at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab at the new lab. From left are Capt. Winston Scott, executive director of the Florida Space Authority; Dr. Robert J. Ferl, director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida; Charlie Quincy, chief of the Biological Sciences Office, Kennedy Space Center; Jose Perez-Morales, NASA Project Manager for the Space Life Sciences Lab; Jim Kennedy, director of the Kennedy Space Center; The Honorable Toni Jennings, lieutenant governor of the state of Florida; Frank T. Brogan, president of the Florida Atlantic University; and Dr. Samuel Durrance, executive director of the Florida Space Research Institute. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

NASA Image and Video Library

2003-11-19

KENNEDY SPACE CENTER, FLA. - Officials of the NASA-Kennedy Space Center and the state of Florida pose for a group portrait at a dedication and ribbon-cutting ceremony for the Space Life Sciences Lab at the new lab. From left are Capt. Winston Scott, executive director of the Florida Space Authority; Dr. Robert J. Ferl, director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida; Charlie Quincy, chief of the Biological Sciences Office, Kennedy Space Center; Jose Perez-Morales, NASA Project Manager for the Space Life Sciences Lab; Jim Kennedy, director of the Kennedy Space Center; The Honorable Toni Jennings, lieutenant governor of the state of Florida; Frank T. Brogan, president of the Florida Atlantic University; and Dr. Samuel Durrance, executive director of the Florida Space Research Institute. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

Meet EPA Exposure Scientist and National Program Director Dr. Tina Bahadori

EPA Pesticide Factsheets

Dr. Tina Bahadori leads EPA's Chemical Safety for Sustainability research program. She is an exposure scientist with extensive expertise developing and managing research programs that integrate exposure with health sciences.

Enhancing Price Response Programs through Auto-DR: California's 2007 Implementation Experience

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kiliccote, Sila; Wikler, Greg; Chiu, Albert

2007-12-18

This paper describes automated demand response (Auto-DR) activities, an innovative effort in California to ensure that DR programs produce effective and sustainable impacts. Through the application of automation and communication technologies coupled with well-designed incentives and DR programs such as Critical Peak Pricing (CPP) and Demand Bidding (DBP), Auto-DR is opening up the opportunity for many different types of buildings to effectively participate in DR programs. We present the results of Auto-DR implementation efforts by the three California investor-owned utilities for the Summer of 2007. The presentation emphasizes Pacific Gas and Electric Company's (PG&E) Auto-DR efforts, which represents the largestmore » in the state. PG&E's goal was to recruit, install, test and operate 15 megawatts of Auto-DR system capability. We describe the unique delivery approaches, including optimizing the utility incentive structures designed to foster an Auto-DR service provider community. We also show how PG&E's Critical Peak Pricing (CPP) and Demand Bidding (DBP) options were called and executed under the automation platform. Finally, we show the results of the Auto-DR systems installed and operational during 2007, which surpassed PG&E's Auto-DR goals. Auto-DR is being implemented by a multi-disciplinary team including the California Investor Owned Utilities (IOUs), energy consultants, energy management control system vendors, the Lawrence Berkeley National Laboratory (LBNL), and the California Energy Commission (CEC).« less

Agonistic Human Monoclonal Antibodies against Death Receptor 4 (DR4) | NCI Technology Transfer Center | TTC

Cancer.gov

The National Cancer Institute is seeking parties interested in licensing human monoclonal antibodies (mAbs) that bind to death receptor 4 ("DR4"). The tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) and its functional receptors, DR4 and DR5, have been recognized as promising targets for cancer treatment.

Dr. Kenneth Sudduth: A giant pioneering precision agriculture

USDA-ARS?s Scientific Manuscript database

Dr. Ken Sudduth is nationally and internationally recognized for his precision agriculture research and leadership, especially in the areas of soil sensing and assessment of spatial variability for site-specific management. His many noteworthy contributions include novel techniques and methodology f...

Dr. Andrew Foster: A Literature Review

ERIC Educational Resources Information Center

Runnels, Joel

2017-01-01

Often compared to Laurent Clerc, Thomas Gallaudet, and Alexander Graham Bell, Dr. Andrew Foster was a deaf African American who founded 32 schools for the deaf in 13 African nations. The 60th anniversary of his arrival in Liberia and Ghana and the 30th anniversary of his tragic death in a Rwanda airplane accident both occur in 2017. Renewed…

Dr. John J. Stephens, Jr., metallurgist extraordinaire.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hosking, Floyd Michael

The organizers of the Dr. John J. Stephens, Jr. Memorial Symposium: Deformation and Interfacial Phenomena in Advanced High-Temperature Materials are honoring the memory of Dr. Stephens and his many technical contributions that were accomplished over a relatively brief twenty year career. His research spanned the areas of creep and deformation of metals, dispersion-strengthened alloys and their properties, metal matrix composite materials, processing and properties of refractory metals, joining of ceramic-ceramic and metal-ceramic systems, active braze alloy development, and mechanical modeling of soldered and brazed assemblies. The purpose of this presentation is to highlight his research and engineering accomplishments, particularly duringmore » his professional career at Sandia National Laboratories in Albuquerque, NM.« less

[Study on correlation between HLA-A, B, DR alleles and Duchenne muscular dystrophy].

PubMed

Chen, Wei; Xiao, Lulu; Zhang, Cheng; Wu, Hong-ling

2007-10-01

To analyze the polymorphism of HLA-A, B and DR alleles of Duchenne muscular dystrophy (DMD) patients in Han nationality of South China and to discuss the role of immune and genetic factors in the pathogenesis of DMD and muscular fiber necrosis. Polymerase chain reaction-reverse sequence specific oligonucleotide (PCR-RSSO) and National Marrow Donor Program (NMDP) were used to analyze the polymorphism of HLA-A,B and DR alleles of 113 DMD patients and 406 normal controls in Han nationality of South China. The frequencies of HLA-A24, A30 alleles in DMD group were 11.25% and 5.46% respectively, indicating notable difference (P=0.001, < 0.01) from 22.16% and 0.87% of control group; the frequencies of HLA-B13, B15, B61 and B62 alleles in DMD group were 12.26%, 16.92%, 0.44% and 0.44%, indicating a notable difference (P=0.016, < 0.01, 0.001) from 6.76%, 1.49%, 4.79% and 5.05% of control group; the frequencies of HLA-DR04, DR07, DR12 alleles in DMD group were 17.45%, 6.40% and 19.62%, indicating a notable difference (P=0.018, < 0.01, 0.012) from 10.67%, 2.24% and 11.92% of control group. There are significant differences in the HLA gene frequencies between DMD patients and normal controls. These results suggest that HLA genotype relates to the muscular necrosis and the pathogenesis of DMD.

Science Labs: Beyond Isolationism

ERIC Educational Resources Information Center

Cavanagh, Sean

2007-01-01

A national study released in 2005 concluded that most high school students are not exposed to high quality science labs because of these reasons: (a) poor school facilities and organizations; (b) weak teacher preparation; (c) poor design; (d) cluttered state standards; (e) little representation on state tests; and (f) scarce evidence of what…

Commerce Lab - A program of commercial flight opportunities

NASA Technical Reports Server (NTRS)

Robertson, J.; Atkins, H. L.; Williams, J. R.

1985-01-01

Commerce Lab is conceived as an adjunct to the National Space Transportation System (NSTS) by providing a focal point for commercial missions which could utilize existing NSTS carrier and resource capabilities for on-orbit experimentation in the microgravity sciences. In this context, the Commerce Lab program provides mission planning for private sector involvement in the space program, in general, and the commercial exploitation of the microgravity environment for materials processing research and development. It is expected that Commerce Lab will provide a logical transition between currently planned NSTS missions and future microgravity science and commercial R&D missions centered around the Space Station. The present study identifies candidate Commerce Lab flight experiments and their development status and projects a mission traffic model that can be used in commercial mission planning.

High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

ScienceCinema

Goyal, Amit [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

2018-04-27

Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grain supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy 100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.

High Temperature Superconductors: From Delivery to Applications (Presentation from 2011 Ernest Orlando Lawrence Award-winner, Dr. Amit Goyal, and including introduction by Energy Secretary, Dr. Steven Chu)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Goyal, Amit

Dr. Amit Goyal, a high temperature superconductivity (HTS) researcher at Oak Ridge National Laboratory, was named a 2011 winner of the Department of Energy's Ernest Orlando Lawrence Award honoring U.S. scientists and engineers for exceptional contributions in research and development supporting DOE and its mission. Winner of the award in the inaugural category of Energy Science and Innovation, Dr. Goyal was cited for his work in 'pioneering research and transformative contributions to the field of applied high temperature superconductivity, including fundamental materials science advances and technical innovations enabling large-scale applications of these novel materials.' Following his basic research in grain-to-grainmore » supercurrent transport, Dr. Goyal focused his energy in transitioning this fundamental understanding into cutting-edge technologies. Under OE sponsorship, Dr. Goyal co-invented the Rolling Assisted Bi-Axially Textured Substrate technology (RABiTS) that is used as a substrate for second generation HTS wires. OE support also led to the invention of Structural Single Crystal Faceted Fiber Substrate (SSIFFS) and the 3-D Self Assembly of Nanodot Columns. These inventions and associated R&D resulted in 7 R&D 100 Awards including the 2010 R&D Magazine's Innovator of the Year Award, 3 Federal Laboratory Consortium Excellence in Technology Transfer National Awards, a DOE Energy 100 Award and many others. As a world authority on HTS materials, Dr. Goyal has presented OE-sponsored results in more than 150 invited talks, co-authored more than 350 papers and is a fellow of 7 professional societies.« less

Dr. Kenneth Plotkins Myriad Contribution to the National Aeronautics and Space Administrations Supersonic Mission

NASA Technical Reports Server (NTRS)

Haering, Edward A.

2017-01-01

The world as a whole and NASA in particular, owes a large debt of gratitude to Dr. Kenneth Plotkin for his decades of service in the field of sonic boom research and advancement of quiet supersonic transportation. This presentation will highlight the contributions of Dr. Plotkin to a myriad of NASA projects. One of the largest efforts was the assembly and continual improvement of sonic boom propagation software tools, collectively called PCBoom, which allowed the analysis of real and imagined vehicles from Mach cutoff conditions to the hypersonic.

Love the Lab, Hate the Lab Report?

ERIC Educational Resources Information Center

Bjorn, Genevive

2018-01-01

In the author's large, urban high school, enrollment in a laboratory science is mandatory. While the student participation rate for lab activities is over 98%, the turn-in rate for traditional lab reports averages just 35% to 85%. Those students who don't produce a lab report miss a critical opportunity to improve their skills in scientific…

74. ARAII. Dr. William Zinn of combustion engineering company and ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

74. ARA-II. Dr. William Zinn of combustion engineering company and others at controls of SL-1. August 8, 1959. Ineel photo no. 59-4109. - Idaho National Engineering Laboratory, Army Reactors Experimental Area, Scoville, Butte County, ID

ORAC-DR -- Programmer's Guide

NASA Astrophysics Data System (ADS)

Jenness, Tim; Economou, Frossie; Cavanagh, Brad

ORAC-DR is a general purpose automatic data reduction pipeline environment. This document describes how to modify data reduction recipes and how to add new instruments. For a general overview of ORAC-DR see SUN/230. For specific information on how to reduce the data for a particular instrument, please consult the appropriate ORAC-DR instrument guide.

The Marin Lab at the Dawn of Cognitive Neuropsychology.

PubMed

Schwartz, Myrna F

2015-09-01

This essay discusses the intellectual developments in psychology, linguistics, and behavioral neurology that shaped Oscar Marin's approach to disorders of high cortical function. As Chief of Neurology at Baltimore City Hospitals in the 1970s, Dr Marin teamed with biopsychologist Eleanor Saffran and the author in seminal studies of acquired language disorders (aphasia) centering on core processes of syntax and semantics, and rejecting premature reductionism. The philosophical and methodological principles that motivated these studies are traced through the author's personal recollections and the published writings of the Marin lab. These principles came to be associated with the cognitive neuropsychology school of research and have important linkages to contemporary work in the neuroscience of aphasia and related cognitive disorders.

Gaia DR2 documentation

NASA Astrophysics Data System (ADS)

van Leeuwen, F.; de Bruijne, J. H. J.; Arenou, F.; Bakker, J.; Blomme, R.; Busso, G.; Cacciari, C.; Castañeda, J.; Cellino, A.; Clotet, M.; Comoretto, G.; Eyer, L.; González-Núñez, J.; Guy, L.; Hambly, N.; Hobbs, D.; van Leeuwen, M.; Luri, X.; Manteiga, M.; Pourbaix, D.; Roegiers, T.; Salgado, J.; Sartoretti, P.; Tanga, P.; Ulla, A.; Utrilla Molina, E.; Abreu, A.; Altmann, M.; Andrae, R.; Antoja, T.; Audard, M.; Babusiaux, C.; Bailer-Jones, C. A. L.; Barache, C.; Bastian, U.; Beck, M.; Berthier, J.; Bianchi, L.; Biermann, M.; Bombrun, A.; Bossini, D.; Breddels, M.; Brown, A. G. A.; Busonero, D.; Butkevich, A.; Cantat-Gaudin, T.; Carrasco, J. M.; Cheek, N.; Clementini, G.; Creevey, O.; Crowley, C.; David, M.; Davidson, M.; De Angeli, F.; De Ridder, J.; Delbò, M.; Dell'Oro, A.; Diakité, S.; Distefano, E.; Drimmel, R.; Durán, J.; Evans, D. W.; Fabricius, C.; Fabrizio, M.; Fernández-Hernández, J.; Findeisen, K.; Fleitas, J.; Fouesneau, M.; Galluccio, L.; Gracia-Abril, G.; Guerra, R.; Gutiérrez-Sánchez, R.; Helmi, A.; Hernandez, J.; Holl, B.; Hutton, A.; Jean-Antoine-Piccolo, A.; Jevardat de Fombelle, G.; Joliet, E.; Jordi, C.; Juhász, Á.; Klioner, S.; Löffler, W.; Lammers, U.; Lanzafame, A.; Lebzelter, T.; Leclerc, N.; Lecoeur-Taïbi, I.; Lindegren, L.; Marinoni, S.; Marrese, P. M.; Mary, N.; Massari, D.; Messineo, R.; Michalik, D.; Mignard, F.; Molinaro, R.; Molnár, L.; Montegriffo, P.; Mora, A.; Mowlavi, N.; Muinonen, K.; Muraveva, T.; Nienartowicz, K.; Ordenovic, C.; Pancino, E.; Panem, C.; Pauwels, T.; Petit, J.; Plachy, E.; Portell, J.; Racero, E.; Regibo, S.; Reylé, C.; Rimoldini, L.; Ripepi, V.; Riva, A.; Robichon, N.; Robin, A.; Roelens, M.; Romero-Gómez, M.; Sarro, L.; Seabroke, G.; Segovia, J. C.; Siddiqui, H.; Smart, R.; Smith, K.; Sordo, R.; Soria, S.; Spoto, F.; Stephenson, C.; Turon, C.; Vallenari, A.; Veljanoski, J.; Voutsinas, S.

2018-04-01

The second Gaia data release, Gaia DR2, encompasses astrometry, photometry, radial velocities, astrophysical parameters (stellar effective temperature, extinction, reddening, radius, and luminosity), and variability information plus astrometry and photometry for a sample of pre-selected bodies in the solar system. The data collected during the first 22 months of the nominal, five-year mission have been processed by the Gaia Data Processing and Analysis Consortium (DPAC), resulting into this second data release. A summary of the release properties is provided in Gaia Collaboration et al. (2018b). The overall scientific validation of the data is described in Arenou et al. (2018). Background information on the mission and the spacecraft can be found in Gaia Collaboration et al. (2016), with a more detailed presentation of the Radial Velocity Spectrometer (RVS) in Cropper et al. (2018). In addition, Gaia DR2 is accompanied by various, dedicated papers that describe the processing and validation of the various data products. Four more Gaia Collaboration papers present a glimpse of the scientific richness of the data. In addition to this set of refereed publications, this documentation provides a detailed, complete overview of the processing and validation of the Gaia DR2 data. Gaia data, from both Gaia DR1 and Gaia DR2, can be retrieved from the Gaia archive, which is accessible from https://archives.esac.esa.int/gaia. The archive also provides various tutorials on data access and data queries plus an integrated data model (i.e., description of the various fields in the data tables). In addition, Luri et al. (2018) provide concrete advice on how to deal with Gaia astrometry, with recommendations on how best to estimate distances from parallaxes. The Gaia archive features an enhanced visualisation service which can be used for quick initial explorations of the entire Gaia DR2 data set. Pre-computed cross matches between Gaia DR2 and a selected set of large surveys are

75 FR 28236 - Marine Mammals; File No. 13602

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-20

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XK54 Marine Mammals; File No. 13602 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... hereby given that Dr. Terrie Williams, Long Marine Lab, Institute of Marine Sciences, University of...

76 FR 7823 - Marine Mammals; File No. 13602

Federal Register 2010, 2011, 2012, 2013, 2014

2011-02-11

... DEPARTMENT OF COMMERCE National Oceanic and Atmospheric Administration RIN 0648-XK54 Marine Mammals; File No. 13602 AGENCY: National Marine Fisheries Service (NMFS), National Oceanic and Atmospheric... that Dr. Terrie Williams, Long Marine Lab, Institute of Marine Sciences, University of California at...

CHEMICAL AND TOXICOLOGICAL EVALUATION OF CHLORINATED AND OZONATED-CHLORINATED DRINKING WATER: A COLLABORATION OF THE FOUR NATIONAL LABS OF THE U. S. EPA

EPA Science Inventory

CHEMICAL AND TOXICOLOGICAL EVALUATION OF CHLORINATED AND OZONATED-CHLORINATED DRINKING WATER: A COLLABORATION OF THE FOUR NATIONAL LABS OF THE U.S. EPA
Susan D. Richardson1, Linda K. Teuschler2, Alfred D. Thruston, Jr.,1 Thomas Speth3, Richard J. Miltner3, Glenn Rice2, Kathle...

A tribute to Dr. Gordon Hisashi Sato (December 24, 1927-March 31, 2017).

PubMed

Sato, J Denry; Okamoto, Tetsuji; Barnes, David; Hayashi, Jun; Serrero, Ginette; McKeehan, Wallace L

2018-03-01

Gordon H. Sato, an innovator in mammalian tissue culture and integrated cellular physiology, passed away in 2017. In tribute to Dr. Sato, In Vitro Cellular and Developmental Biology-Animal presents a collection of invited remembrances from six colleagues whose associations with Dr. Sato spanned more than 40 years. Dr. Sato was a past president of the Tissue Culture Association (now the Society for In Vitro Biology), editor-in-chief of In Vitro Cellular and Developmental Biology (1987-1991), and the recipient of the lifetime achievement award from the Society for In Vitro Biology (2002). He was elected to the US National Academy of Sciences in 1984.

Conducting On-orbit Gene Expression Analysis on ISS: WetLab-2

NASA Technical Reports Server (NTRS)

Parra, Macarena; Almeida, Eduardo; Boone, Travis; Jung, Jimmy; Lera, Matthew P.; Ricco, Antonio; Souza, Kenneth; Wu, Diana; Richey, C. Scott

2013-01-01

WetLab-2 will enable expanded genomic research on orbit by developing tools that support in situ sample collection, processing, and analysis on ISS. This capability will reduce the time-to-results for investigators and define new pathways for discovery on the ISS National Lab. The primary objective is to develop a research platform on ISS that will facilitate real-time quantitative gene expression analysis of biological samples collected on orbit. WetLab-2 will be capable of processing multiple sample types ranging from microbial cultures to animal tissues dissected on orbit. WetLab-2 will significantly expand the analytical capabilities onboard ISS and enhance science return from ISS.

Dr. Daniel Carter

NASA Technical Reports Server (NTRS)

1998-01-01

Dr. Daniel Carter, president of New Century Pharmaceuticals in Huntsville, Al, is one of three principal investigators in NASA's microgravity protein crystal growth program. Dr. Carter's experties is in albumins. Albumins are proteins in the bloodstream that transport materials, drugs, nutrients, and wastes. Photo credit: NASA/Marshall Space Flight Center

Nonlocal Continuum Theory for Dislocation and Fracture.

DTIC Science & Technology

1984-04-01

Pasadena, California 91109 Washington, D.C. 20553 Professor Paul M. Naghdi National Academy of Sciences University of California National Research...Burt Paul University of Pennsylvania Dr. Samuel B. Batdorf Towne School of Civil and University of California Mechanical Engineering School of...Pittsburgh, Pennsylvania 15213 474:NP:716:lab 78u474 -619 Universities (Con’t) Universities (Con’t) Dr. V. K. Varadan Professor V. 9. Neubert Ohio

Interaction of a Dislocation with a Crack.

DTIC Science & Technology

1983-08-01

Agency Pasadena, California 91109 Washington, D.C. 20553 Professor Paul M. Naghdi National Academy of Sciences University of California National...Professor Burt Paul University of Pennsylvania Dr. Samuel B. Batdorf Towne School of Civil and University of California Mechanical Engineering School of...14214 Pittsburgh, Pennsylvania 15213 474:NP:716:lab 78u474-619 Universities (Con’t) Universities (Con’t) Dr. V. K. Varadan Professor V. H. Neubert

Crack Velocities in Natural Rubber.

DTIC Science & Technology

1982-05-01

vulcanized natural rubber (3). The surprisingly low value for natural rubber was attributed to highly anisotropic elastic behavior at high strains...Dr. R.L. Rabie Hercules Incorporated WX-2, MS-952 Alleghany Ballistic Lab Los Alamos National Lab. P.O. Box 210 P.O. Box 1663 Washington, D.C. 21502

Dual Agonist Surrobody Simultaneously Activates Death Receptors DR4 and DR5 to Induce Cancer Cell Death.

PubMed

Milutinovic, Snezana; Kashyap, Arun K; Yanagi, Teruki; Wimer, Carina; Zhou, Sihong; O'Neil, Ryann; Kurtzman, Aaron L; Faynboym, Alexsandr; Xu, Li; Hannum, Charles H; Diaz, Paul W; Matsuzawa, Shu-ichi; Horowitz, Michael; Horowitz, Lawrence; Bhatt, Ramesh R; Reed, John C

2016-01-01

Death receptors of the TNF family are found on the surface of most cancer cells and their activation typically kills cancer cells through the stimulation of the extrinsic apoptotic pathway. The endogenous ligand for death receptors 4 and 5 (DR4 and DR5) is TNF-related apoptosis-inducing ligand, TRAIL (Apo2L). As most untransformed cells are not susceptible to TRAIL-induced apoptosis, death receptor activators have emerged as promising cancer therapeutic agents. One strategy to stimulate death receptors in cancer patients is to use soluble human recombinant TRAIL protein, but this agent has limitations of a short half-life and decoy receptor sequestration. Another strategy that attempted to evade decoy receptor sequestration and to provide improved pharmacokinetic properties was to generate DR4 or DR5 agonist antibodies. The resulting monoclonal agonist antibodies overcame the limitations of short half-life and avoided decoy receptor sequestration, but are limited by activating only one of the two death receptors. Here, we describe a DR4 and DR5 dual agonist produced using Surrobody technology that activates both DR4 and DR5 to induce apoptotic death of cancer cells in vitro and in vivo and also avoids decoy receptor sequestration. This fully human anti-DR4/DR5 Surrobody displays superior potency to DR4- and DR5-specific antibodies, even when combined with TRAIL-sensitizing proapoptotic agents. Moreover, cancer cells were less likely to acquire resistance to Surrobody than either anti-DR4 or anti-DR5 monospecific antibodies. Taken together, Surrobody shows promising preclinical proapoptotic activity against cancer cells, meriting further exploration of its potential as a novel cancer therapeutic agent. ©2015 American Association for Cancer Research.

Dual agonist Surrobody™ simultaneously activates death receptors DR4 and DR5 to induce cancer cell death

PubMed Central

Milutinovic, Snezana; Kashyap, Arun K.; Yanagi, Teruki; Wimer, Carina; Zhou, Sihong; O' Neil, Ryann; Kurtzman, Aaron L.; Faynboym, Alexsandr; Xu, Li; Hannum, Charles H.; Diaz, Paul W.; Matsuzawa, Shu-ichi; Horowitz, Michael; Horowitz, Lawrence; Bhatt, Ramesh R.; Reed, John C.

2015-01-01

Death receptors of the Tumor Necrosis Factor (TNF) family are found on surface of most cancer cells and their activation typically kills cancer cells through the stimulation of the extrinsic apoptotic pathway. The endogenous ligand for death receptors-4 and -5 (DR4 and DR5) is Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand, TRAIL (Apo2L). Since most untransformed cells are not susceptible to TRAIL-induced apoptosis, death receptor activators have emerged as promising cancer therapeutic agents. One strategy to stimulate death receptors in cancer patients is to use soluble human recombinant TRAIL protein, but this agent has limitations of a short half-life and decoy receptor sequestration. Another strategy that attempted to evade decoy receptor sequestration and to provide improved pharmacokinetic properties was to generate DR4 or DR5 agonist antibodies. The resulting monoclonal agonist antibodies overcame the limitations of short half-life and avoided decoy receptor sequestration, but are limited by activating only one of the two death receptors. Here, we describe a DR4 and DR5 dual agonist produced using Surrobody™ technology that activates both DR4 and DR5 to induce apoptotic death of cancer cells in vitro and in vivo and also avoids decoy receptor sequestration. This fully human anti-DR4/DR5 Surrobody displays superior potency to DR4- and DR5-specific antibodies, even when combined with TRAIL-sensitizing pro-apoptotic agents. Moreover, cancer cells were less likely to acquire resistance to Surrobody than either anti-DR4 or anti-DR5 mono-specific antibodies. Taken together, Surrobody shows promising preclinical pro-apoptotic activity against cancer cells, meriting further exploration of its potential as a novel cancer therapeutic agent. PMID:26516157

Oligonucleotide-genotyping as a method of detecting the HLA-DR2 (DRw15)-Dw2, -DR2 (DRw15)-Dw12, -DR4-Dw15, and -DR4-D"KT2" haplotypes in the Japanese population.

PubMed

Obata, F; Ito, I; Kaneko, T; Ohkubo, M; Ishimoto, A L; Abe, A; Kashiwagi, N

1989-05-01

We synthesized pairs of four different oligonucleotides, F22, F29, F42, and F158, to analyse the HLA-DR2 (DRw15) and -DR4 haplotypes in the Japanese population. After enzymatically amplifying the HLA-DRB1 gene, we hybridized the oligonucleotide probes with DNA extracted from 42 donors. Hybridization was completed between F22 and the DNA of haplotype DR2 (DRw15)-Dw2, between F29 and the DNA of DR2 (DRw15)-Dw12, between F42 and the DNA of DR4-D"KT2", and between F158 and the DNA of DR4-Dw15. In keeping with the nucleotide sequences of the probes, F29 hybridized also with DNA from the DR9-Dw23 haplotype and F158 with that from some of the DRw8 haplotypes (DRw8-Dw8.3) in the Japanese population. Results of this study demonstrate that the four oligonucleotides make useful probes for detecting the haplotypes above.

5. View of middle DR 2 antenna with DR 1 ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

5. View of middle DR 2 antenna with DR 1 antenna in background. Photograph shows on left side at bottom foundation berm and along right side bottom stanchion concrete foundations at bottom structural steel assembly. - Clear Air Force Station, Ballistic Missile Early Warning System Site II, One mile west of mile marker 293.5 on Parks Highway, 5 miles southwest of Anderson, Anderson, Denali Borough, AK

Large Customers (DR Sellers)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kiliccot, Sila

2011-10-25

State of the large customers for demand response integration of solar and wind into electric grid; openADR; CAISO; DR as a pseudo generation; commercial and industrial DR strategies; California regulations

Then & Now: Research Pays Off for All Americans / Dr. Virginia Apgar: Keeping Score at Baby's First Cry | NIH ...

MedlinePlus

... Elizabeth Wilcox, Archives & Special Collections, Columbia University Health Sciences Library Dr. Apgar's advice to mothers is summarized in ... more about Dr. Apgar through the Profiles in Science program of the National Library of Medicine and through the NLM exhibit Changing ...

NOAA Photo Library - Meet the Photographers/Dr. Picciolo (Tony)

Science.gov Websites

Biology Group Leader at the National Oceanographic Data center. Current primary emphasis is in coral reef Maryland. His first introduction to marine biology was as a graduate student, where with his professor, Dr these years he also worked on reproductive biology and behavior of southeast Asian fishes, bioacoustics

The Marin Lab at the Dawn of Cognitive Neuropsychology

PubMed Central

Schwartz, Myrna F.

2015-01-01

This essay discusses the intellectual developments in psychology, linguistics, and behavioral neurology that shaped Oscar Marin’s approach to disorders of high cortical function. As Chief of Neurology at Baltimore City Hospitals in the 1970s, Dr Marin teamed with biopsychologist Eleanor Saffran and the author in seminal studies of acquired language disorders (aphasia) centering on core processes of syntax and semantics, and rejecting premature reductionism. The philosophical and methodological principles that motivated these studies are traced through the author’s personal recollections and the published writings of the Marin lab. These principles came to be associated with the cognitive neuropsychology school of research and have important linkages to contemporary work in the neuroscience of aphasia and related cognitive disorders. PMID:26413736

Postdoctoral Fellow | Center for Cancer Research

Cancer.gov

A new Postdoctoral Fellow position is immediately available in the laboratory of Dr. Terry Yamaguchi at the National Cancer Institute. Dr.Yamaguchi's lab investigates how secreted growth factors regulate the gene regulatory networks that control the fate of embryonic and adult stem cells. Current projects focus on understanding how Wnts and Fgfs regulate the formation and differentiation of the neuromesodermal progenitor (NMP), a multipotent embryonic cell that generates the spinal cord neurons and musculoskeletal system of the body. Using a combination of mouse genetics, mouse and human embryonic stem cell in vitro differentiation, and genomic, proteomic and biochemical approaches, Dr. Yamaguchi’s lab is investigating the molecular mechanisms underlying the activity of key transcriptional determinants of NMP development.

Dr. von Braun With Management Team

NASA Technical Reports Server (NTRS)

1961-01-01

Dr. von Braun is shown in this photograph, which was probably taken in the early 1960s, with members of his management team. Pictured from left to right are, Werner Kuers, Director of the Manufacturing Engineering Division; Dr. Walter Haeussermarn, Director of the Astrionics Division; Dr. William Mrazek, Propulsion and Vehicle Engineering Division; Dr. von Braun; Dieter Grau, Director of the Quality Assurance Division; Dr. Oswald Lange, Director of the Saturn Systems Office; and Erich Neubert , Associate Deputy Director for Research and Development.

Dr. Faustus: Theist or Atheist?

ERIC Educational Resources Information Center

Karim, Shah Mohammad Sanaul; Fathema, Fawzia; Hakim, Abdul

2015-01-01

Dr. Faustus is the greatest but the most controversial of Marlowe's plays. Among the causes of controversy, whether Dr. Faustus is an atheist or theist deserves utmost attention. This paper is intended to deal with the issue. Though at various stages of the development of the action, Dr. Faustus abjures Trinity, resorts to necromancy, becomes…

Berkeley Lab Training

Science.gov Websites

Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Help Berkeley Lab Training Welcome Welcome to Berkeley Lab Training! Login to access your LBNL Training Profile. This provides quick access to all of the courses you need. Look below, to learn about different types of training available at

Using National Instruments LabVIEW[TM] Education Edition in Schools

ERIC Educational Resources Information Center

Butlin, Chris A.

2011-01-01

With the development of LabVIEW[TM] Education Edition schools can now provide experience of using this widely used software. Here, a few of the many applications that students aged around 11 years and over could develop are outlined in the resulting front panel screen displays and block diagrams showing the associated graphical programmes, plus a…

EarthLabs - Investigating Hurricanes: Earth's Meteorological Monsters

NASA Astrophysics Data System (ADS)

McDaris, J. R.; Dahlman, L.; Barstow, D.

2007-12-01

Earth science is one of the most important tools that the global community needs to address the pressing environmental, social, and economic issues of our time. While, at times considered a second-rate science at the high school level, it is currently undergoing a major revolution in the depth of content and pedagogical vitality. As part of this revolution, labs in Earth science courses need to shift their focus from cookbook-like activities with known outcomes to open-ended investigations that challenge students to think, explore and apply their learning. We need to establish a new model for Earth science as a rigorous lab science in policy, perception, and reality. As a concerted response to this need, five states, a coalition of scientists and educators, and an experienced curriculum team are creating a national model for a lab-based high school Earth science course named EarthLabs. This lab course will comply with the National Science Education Standards as well as the states' curriculum frameworks. The content will focus on Earth system science and environmental literacy. The lab experiences will feature a combination of field work, classroom experiments, and computer access to data and visualizations, and demonstrate the rigor and depth of a true lab course. The effort is being funded by NOAA's Environmental Literacy program. One of the prototype units of the course is Investigating Hurricanes. Hurricanes are phenomena which have tremendous impact on humanity and the resources we use. They are also the result of complex interacting Earth systems, making them perfect objects for rigorous investigation of many concepts commonly covered in Earth science courses, such as meteorology, climate, and global wind circulation. Students are able to use the same data sets, analysis tools, and research techniques that scientists employ in their research, yielding truly authentic learning opportunities. This month-long integrated unit uses hurricanes as the story line by

Enrico Fermi Awards Ceremony for Dr. Mildred S. Dresselhaus and Dr. Burton Richter, May 2012 (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

ScienceCinema

Chu, Steven [Dept. of Energy (DOE), Washington DC (United States)

2018-06-12

The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On May 7, 2012 it was conferred upon two exceptional scientists: Dr. Mildred Dresselhaus, 'for her scientific leadership, her major contributions to science and energy policy, her selfless work in science education and the advancement of diversity in the scientific workplace, and her highly original and impactful research,' and Dr. Burton Richter, 'for the breadth of his influence in the multiple disciplines of accelerator physics and particle physics, his profound scientific discoveries, his visionary leadership as SLAC Director, his leadership of science, and his notable contributions in energy and public policy.' Dr. John Holder, Director of the White House Office of Science and Technology Policy, opened the ceremony, and Dr. Bill Brinkman, Director of DOE's Office of Science introduced the main speaker, Dr. Steven Chu, U.S. Energy Secretary.

Special Report: Hazardous Wastes in Academic Labs.

ERIC Educational Resources Information Center

Sanders, Howard J.

1986-01-01

Topics and issues related to toxic wastes in academic laboratories are addressed, pointing out that colleges/universities are making efforts to dispose of hazardous wastes safely to comply with tougher federal regulations. University sites on the Environmental Protection Agency Superfund National Priorities List, costs, and use of lab packs are…

Lab Simulates Outdoor Algae Growth

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Algae can be turned into renewable biofuel, which is why scientists want to discover an inexpensive, fast-growing strain of algae. Scientists at Pacific Northwest National Laboratory have developed a system to speed up this search. The unique climate-simulating system uses temperature controls and multi-colored LED lights to mimic the constantly changing conditions of an outdoor algae pond. By simulating outdoor climates inside the lab, the system saves researchers time and expense.

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Goddard and colleagues at Roswell, New Mexico. Successful test of May 19, 1937. Dr. Robert Goddard is holding the cap and pilot parachute, parts of the successful operation. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

DNA Microarray Wet Lab Simulation Brings Genomics into the High School Curriculum

ERIC Educational Resources Information Center

Campbell, A. Malcolm; Zanta, Carolyn A.; Heyer, Laurie J.; Kittinger, Ben; Gabric, Kathleen M.; Adler, Leslie

2006-01-01

We have developed a wet lab DNA microarray simulation as part of a complete DNA microarray module for high school students. The wet lab simulation has been field tested with high school students in Illinois and Maryland as well as in workshops with high school teachers from across the nation. Instead of using DNA, our simulation is based on pH…

Dr. Gilruth and Dr. Kraft - Mission Control Center (MCC) - Apollo V Launch - MSC

NASA Image and Video Library

1968-01-22

S68-18733 (22 Jan. 1968) --- Dr. Robert R. Gilruth (right), MSC Director, sits with Dr. Christopher C. Kraft Jr., MSC director of flight operations, at his flight operations director console in the Mission Control Center, Building 30, during the Apollo 5 (LM-1/Saturn 204) unmanned space mission.

Antibody Characterization Lab | Office of Cancer Clinical Proteomics Research

Cancer.gov

The Antibody Characterization Lab (ACL), an intramural reference laboratory located at the Frederick National Laboratory for Cancer Research in Frederick, Maryland, thoroughly characterizes monoclonal antibodies or other renewable affinity binding reagents for use in cancer related research.

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Hutchings Goddard (1882-1945). Dr. Goddard has been recognized as the father of American rocketry and as one of the pioneers in the theoretical exploration of space. Robert Hutchings Goddard, born in Worcester, Massachusetts, on October 5, 1882, was theoretical scientist as well as a practical engineer. His dream was the conquest of the upper atmosphere and ultimately space through the use of rocket propulsion. Dr. Goddard, died in 1945, but was probably as responsible for the dawning of the Space Age as the Wrights were for the beginning of the Air Age. Yet his work attracted little serious attention during his lifetime. However, when the United States began to prepare for the conquest of space in the 1950's, American rocket scientists began to recognize the debt owed to the New England professor. They discovered that it was virtually impossible to construct a rocket or launch a satellite without acknowledging the work of Dr. Goddard. More than 200 patents, many of which were issued after his death, covered this great legacy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Goddard on the campus of Clark University, Worcester, Mass. mounting a srocket chamber for the 1915-1916 experiments. Dr. Goddard earned his doctorate at Clark and also taught physics there. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

ScienceCinema

Moniz, Ernest; Dehmer, Patricia

2018-05-04

The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of the research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.

Making the Grid "Smart" Through "Smart" Microgrids: Real-Time Power Management of Microgrids with Multiple Distributed Generation Sources Using Intelligent Control

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nehrir, M. Hashem

In this Project we collaborated with two DOE National Laboratories, Pacific Northwest National Lab (PNNL) and Lawrence Berkeley National Lab (LBL). Dr. Hammerstrom of PNNL initially supported our project and was on the graduate committee of one of the Ph.D. students (graduated in 2014) who was supported by this project. He is also a committee member of a current graduate student of the PI who was supported by this project in the last two years (August 2014-July 2016). The graduate student is now supported be the Electrical and Computer Engineering (ECE) Department at Montana State University (MSU). Dr. Chris Marneymore » of LBL provided actual load data, and the software WEBOPT developed at LBL for microgrid (MG) design for our project. NEC-Labs America, a private industry, also supported our project, providing expert support and modest financial support. We also used the software “HOMER,” originally developed at the National Renewable Energy Laboratory (NREL) and the most recent version made available to us by HOMER Energy, Inc., for MG (hybrid energy system) unit sizing. We compared the findings from WebOpt and HOMER and designed appropriately sized hybrid systems for our case studies. The objective of the project was to investigate real-time power management strategies for MGs using intelligent control, considering maximum feasible energy sustainability, reliability and efficiency while, minimizing cost and undesired environmental impact (emissions). Through analytic and simulation studies, we evaluated the suitability of several heuristic and artificial-intelligence (AI)-based optimization techniques that had potential for real-time MG power management, including genetic algorithms (GA), ant colony optimization (ACO), particle swarm optimization (PSO), and multi-agent systems (MAS), which is based on the negotiation of smart software-based agents. We found that PSO and MAS, in particular, distributed MAS, were more efficient and better suited for our work

e-Learning - Physics Labs

NASA Astrophysics Data System (ADS)

Mohottala, Hashini

2014-03-01

The general student population enrolled in any college level class is highly diverse. An increasing number of ``nontraditional'' students return to college and most of these students follow distance learning degree programs while engaging in their other commitments, work and family. However, those students tend to avoid taking science courses with labs, mostly because of the incapability of remotely completing the lab components in such courses. In order to address this issue, we have come across a method where introductory level physics labs can be taught remotely. In this process a lab kit with the critical lab components that can be easily accessible are conveniently packed into a box and distributed among students at the beginning of the semester. Once the students are given the apparatus they perform the experiments at home and gather data All communications with reference to the lab was done through an interactive user-friendly webpage - Wikispaces (WikiS). Students who create pages on WikiS can submit their lab write-ups, embed videos of the experiments they perform, post pictures and direct questions to the lab instructor. The students who are enrolled in the same lab can interact with each other through WikiS to discuss labs and even get assistance.

Type 1 diabetes risk for HLA-DR3 haplotypes depends on genotypic context: Association of DPB1 and HLA class I loci among DR3 and DR4 matched Italian patients and controls

PubMed Central

Noble, Janelle A.; Martin, Adelle; Valdes, Ana M.; Lane, Julie A.; Galgani, Andrea; Petrone, Antonio; Lorini, Renata; Pozzilli, Paolo; Buzzetti, Raffaella; Erlich, Henry A.

2008-01-01

Patients with high-risk HLA-DR-DQ genotypes for type 1 diabetes (T1D) were compared to HLA-matched controls to evaluate T1D risk for other HLA loci, including HLA-A, -B, -Cw, and DPB1. Patients (n=133) with high-risk genotypes (DR3/DR3, DR3/DR4, DR4/DR4) were selected from the Lazio (Rome) region of Italy. Screening of more than 9000 subjects from the Lazio region and northern Italy yielded 162 controls with high- T1D-risk haplotypes. Although the overall distributions were not significantly different, allele frequency differences were discovered between the controls from Lazio and those from Northern Italy for some alleles previously shown to affect T1D risk, such as A*3002, DPB1*0301, and DPB1*0402. Therefore, Lazio patient data were compared both to the Lazio subset of controls (n=53) and to the entire group of controls for association analyses. Significant allele frequency differences between patients and DR-DQ-matched controls were found for specific alleles at all loci. Data for the DR3/DR3 subset of patients and controls showed an increase of Cw*0702 in patients. Reduced patient, compared to control, frequencies were seen for several alleles, including A*0101, B*0801, and Cw*0701, all found on the highly-conserved, extended DR3 haplotype known as 8.1 in DR3/DR3, but not DR3/DR4, subgroup. DPB1*0101, often found on 8.1 haplotypes, was also less frequent in DR3/DR3 patients than controls. Analysis of family-based data from the HBDI repository was consistent with the observed results from the Italian subjects, suggesting the presence of a T1D-protective locus at or near A*0101 and a second T1D-protective locus at or near DPB1*0101. These data suggest that T1D risk conferred by the 8.1 haplotype is genotype dependent. PMID:18486765

Commerce Lab - An enabling facility and test bed for commercial flight opportunities

NASA Technical Reports Server (NTRS)

Robertson, Jack; Atkins, Harry L.; Williams, John R.

1986-01-01

Commerce Lab is conceived as an adjunct to the National Space Transportation System (NSTS) by providing a focal point for commercial missions which could utilize existing NSTS carrier and resource capabilities for on-orbit experimentation in the microgravity sciences. In this context, the Commerce Lab provides an enabling facility and test bed for commercial flight opportunities. Commerce Lab program activities to date have focused on mission planning for private sector involvement in the space program to facilitate the commercial exploitation of the microgravity environment for materials processing research and development. It is expected that Commerce Lab will provide a logical transition between currently planned NSTS missions and future microgravity science and commercial R&D missions centered around the Space Station. The present study identifies candidate Commerce Lab flight experiments and their development status and projects a mission traffic model that can be used in commercial mission planning.

Enrico Fermi Awards Ceremony for Dr. Allen J. Bard and Dr. Andrew Sessler, February 2014 (Presentations, including remarks by Energy Secretary, Dr. Ernest Moniz)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Moniz, Ernest; Dehmer, Patricia

The Fermi Award is a Presidential award and is one of the oldest and most prestigious science and technology honors bestowed by the U.S. Government. On February 3, 2014 it was conferred upon two exceptional scientists. The first to be recognized is Dr. Allen J. Bard, 'for international leadership in electrochemical science and technology, for advances in photoelectrochemistry and photocatalytic materials, processes, and devices, and for discovery and development of electrochemical methods including electrogenerated chemiluminescence and scanning electrochemical microscopy.' The other honoree is Dr. Andrew Sessler, 'for advancing accelerators as powerful tools of scientific discovery, for visionary direction of themore » research enterprise focused on challenges in energy and the environment, and for championing outreach and freedom of scientific inquiry worldwide.' Dr. Patricia Dehmer opened the ceremony, and Dr. Ernest Moniz presented the awards.« less

NASA GeneLab Concept of Operations

NASA Technical Reports Server (NTRS)

Thompson, Terri; Gibbs, Kristina; Rask, Jon; Coughlan, Joseph; Smith, Jeffrey

2014-01-01

NASA's GeneLab aims to greatly increase the number of scientists that are using data from space biology investigations on board ISS, emphasizing a systems biology approach to the science. When completed, GeneLab will provide the integrated software and hardware infrastructure, analytical tools and reference datasets for an assortment of model organisms. GeneLab will also provide an environment for scientists to collaborate thereby increasing the possibility for data to be reused for future experimentation. To maximize the value of data from life science experiments performed in space and to make the most advantageous use of the remaining ISS research window, GeneLab will apply an open access approach to conducting spaceflight experiments by generating, and sharing the datasets derived from these biological studies in space.Onboard the ISS, a wide variety of model organisms will be studied and returned to Earth for analysis. Laboratories on the ground will analyze these samples and provide genomic, transcriptomic, metabolomic and proteomic data. Upon receipt, NASA will conduct data quality control tasks and format raw data returned from the omics centers into standardized, annotated information sets that can be readily searched and linked to spaceflight metadata. Once prepared, the biological datasets, as well as any analysis completed, will be made public through the GeneLab Space Bioinformatics System webb as edportal. These efforts will support a collaborative research environment for spaceflight studies that will closely resemble environments created by the Department of Energy (DOE), National Center for Biotechnology Information (NCBI), and other institutions in additional areas of study, such as cancer and environmental biology. The results will allow for comparative analyses that will help scientists around the world take a major leap forward in understanding the effect of microgravity, radiation, and other aspects of the space environment on model organisms

360° Algae Lab Tour at NREL - Narrated

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sweeney, Nick

Explore the National Renewable Energy Laboratory’s algae lab as researcher Nick Sweeney takes you on a 360-degree tour of the algal biofuels research facility. Discover how NREL is growing algae to learn how it can be used as a renewable source of food, fuels, and other products.

Field/Lab Training Workshops in Planetary Geology and Astrobiology for Secondary School Teachers

NASA Astrophysics Data System (ADS)

Treiman, A.; Newsom, H.; Hoehler, T.; Tsairides, C.; Karlstrom, K.; Crossey, L.; Kiefer, W.; Kadel, S.; Garcia-Pichel, F.; Aubele, J.; Crumpler, L.

2003-12-01

, with heightened appreciation, excited, and energetic. The teachers are asked to share their knowledge in their districts (in one case, saving the district thousands of dollars). For the presenters, the workshop format allows personal interactions with the teachers, leading to enhanced appreciation of their perspectives and needs. This year, teacher input assisted with an NSF-sponsored National Park education initiative. And in one case, a meaningful research collaboration has come from these workshops. Logistics is the greatest challenge of this workshop format. Hosts and teaching/lab venues need to be arranged early in sites dictated by science content, not convenience. Travel and lodging must be arranged for teachers and presenters at several sites, usually all distant from the organizing institution. Logistics also dictates that each workshop cannot serve more than about 30 teachers. The depth of knowledge imparted and its long-term effects on the teachers and their districts offsets the small number of teachers reached per year. Authors here are the 2003 organizers and presenters. Many others have organized and presented at past workshops - especially Dr. A.J. Irving of U. Wash. We are grateful for past support from NASA Broker/Facilitator, and now from Sandia National Laboratory and NASA OSS/EPO.

Multiwavelength observations of two B-star nurseries - DR 15 and DR 20

NASA Technical Reports Server (NTRS)

Odenwald, S. F.; Campbell, M. F.; Shivanandan, K.; Schwartz, P.; Fazio, G. G.; Moseley, H.

1990-01-01

New observations of DR 15 and 20 are reported as part of a study of compact H II regions in the Cyg X region. The radio and FIR data for these objects, when combined with (C-12)O maps, IRAS imagery, and optical photographs, provide new insights into the structure of this complex region and the nature of the star-formation process there. The observations show that DR 15 may consist of one or two B0 ZAMS stars whose H I regions have formed a low-density cavity within a molecular cloud. DR 20 appears to be a young OB cluster. The cluster is dominated by an O5.5 ZAMS star and also contains an approximately 3500-yr-old B0 star appearing as a compact H II region, along with weak FIR sources that may be B0-star candidates.

KENNEDY SPACE CENTER, FLA. - The Honorable Toni Jennings (left), lieutenant governor of the state of Florida, and Frank T. Brogan, president of Florida Atlantic University, receive a briefing on the research that will be conducted in the Space Life Sciences Lab from Dr. Robert J. Ferl (right), director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida. Jennings and Brogan are speaking at a dedication and ribbon-cutting ceremony for the lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

NASA Image and Video Library

2003-11-19

KENNEDY SPACE CENTER, FLA. - The Honorable Toni Jennings (left), lieutenant governor of the state of Florida, and Frank T. Brogan, president of Florida Atlantic University, receive a briefing on the research that will be conducted in the Space Life Sciences Lab from Dr. Robert J. Ferl (right), director of Space Agriculture Biotechnology Research and Education (SABRE), University of Florida. Jennings and Brogan are speaking at a dedication and ribbon-cutting ceremony for the lab hosted by NASA-Kennedy Space Center and the state of Florida at the new lab. Completed in August, the facility encompasses more than 100,000 square feet and was formerly known as the Space Experiment Research and Processing Laboratory or SERPL. The state, through the Florida Space Authority, built the research lab which is host to NASA, NASA’s Life Sciences Services contractor Dynamac Corp., Bionetics Corp., and researchers from the University of Florida. Dynamac Corp. leases the facility. The Florida Space Research Institute is responsible for gaining additional tenants from outside the NASA community.

50 Breakthroughs by America's National Labs

DOE R&D Accomplishments Database

2011-01-01

America's National Laboratory system has been changing and improving the lives of millions for more than 80 years. Born at a time of great societal need, this network of Department of Energy Laboratories has now grown into 17 facilities, working together as engines of prosperity and invention. As this list of 50 Breakthroughs attests, National Laboratory discoveries have spawned industries, saved lives, generated new products, fired the imagination, and helped to reveal the secrets of the universe. Rooted in the need to be the best and bring the best, America's National Laboratories have put an American stamp on the past century of science. With equal ingenuity and tenacity, they are now engaged in winning the future.

Successful Transportation Lab-Industry Collaborations Spotlighted at Summit

Science.gov Websites

hosted leaders from the business, government, and research communities at the EERE National Lab Impact prime examples of these win-win partnerships, with major automakers, component manufacturers, and fuel with a keynote address by Ford Motor Company Vice President of Research and Advanced Engineering Ken

KSC-2012-2762

NASA Image and Video Library

2012-05-14

CAPE CANAVERAL, Fla. – Dr. Ray Wheeler explains a plant growth chamber to students in the Life Support and Habitation Systems Lab at the Space Life Sciences Lab facility. The 26 honor students in chemistry and biology and their teachers got a chance to visit a number of high-tech labs at Kennedy Space Center as part of an effort to encourage students in the areas of science, technology, engineering and math. The tenth and eleventh grade students from Terry Parker High School in Jacksonville, Fla., visited a number of vastly different labs during their one-day tour. The group's visit to Kennedy was hosted by the Education Office as part of a nationwide effort by the National Lab Network to help introduce the nation's students to science careers. Photo credit: NASA/Jim Grossmann

Dr Pugh: a poisoner?

PubMed

Paull, J D; Morris, G M

2012-07-01

On 16 February 1845 the Reverend W. H. Browne, rector of St John's Church in Launceston, Van Diemen's Land, wrote in his journal, "My dear Wife died very suddenly almost immediately after and in consequence of taking a preparation of Hyd. Cyan. Acid prepared & supplied by Dr Pugh". This journal entry raises a number of questions. Was Dr Pugh treating a condition which he thought merited that treatment or was it a ghastly mistake? Was Caroline Browne suffering from pulmonary tuberculosis? Was hydrocyanic acid an accepted treatment at that time? Did Mrs Browne take the wrong dose? Was an incorrect concentration of the drug prepared by Dr Pugh? Did he use the wrong pharmacopoeia in preparing the hydrocyanic acid? Why was there no inquest? Only some of these questions can be answered.

A Comparative Study on Real Lab and Simulation Lab in Communication Engineering from Students' Perspectives

ERIC Educational Resources Information Center

Balakrishnan, B.; Woods, P. C.

2013-01-01

Over the years, rapid development in computer technology has engendered simulation-based laboratory (lab) in addition to the traditional hands-on (physical) lab. Many higher education institutions adopt simulation lab, replacing some existing physical lab experiments. The creation of new systems for conducting engineering lab activities has raised…

Kinematic Labs with Mobile Devices

NASA Astrophysics Data System (ADS)

Kinser, Jason M.

2015-07-01

This book provides 13 labs spanning the common topics in the first semester of university-level physics. Each lab is designed to use only the student's smartphone, laptop and items easily found in big-box stores or a hobby shop. Each lab contains theory, set-up instructions and basic analysis techniques. All of these labs can be performed outside of the traditional university lab setting and initial costs averaging less than 8 per student, per lab.

MethLAB

PubMed Central

Kilaru, Varun; Barfield, Richard T; Schroeder, James W; Smith, Alicia K

2012-01-01

Recent evidence suggests that DNA methylation changes may underlie numerous complex traits and diseases. The advent of commercial, array-based methods to interrogate DNA methylation has led to a profusion of epigenetic studies in the literature. Array-based methods, such as the popular Illumina GoldenGate and Infinium platforms, estimate the proportion of DNA methylated at single-base resolution for thousands of CpG sites across the genome. These arrays generate enormous amounts of data, but few software resources exist for efficient and flexible analysis of these data. We developed a software package called MethLAB (http://genetics.emory.edu/conneely/MethLAB) using R, an open source statistical language that can be edited to suit the needs of the user. MethLAB features a graphical user interface (GUI) with a menu-driven format designed to efficiently read in and manipulate array-based methylation data in a user-friendly manner. MethLAB tests for association between methylation and relevant phenotypes by fitting a separate linear model for each CpG site. These models can incorporate both continuous and categorical phenotypes and covariates, as well as fixed or random batch or chip effects. MethLAB accounts for multiple testing by controlling the false discovery rate (FDR) at a user-specified level. Standard output includes a spreadsheet-ready text file and an array of publication-quality figures. Considering the growing interest in and availability of DNA methylation data, there is a great need for user-friendly open source analytical tools. With MethLAB, we present a timely resource that will allow users with no programming experience to implement flexible and powerful analyses of DNA methylation data. PMID:22430798

Pathogenesis of Human Diffusely Adhering Escherichia coli Expressing Afa/Dr Adhesins (Afa/Dr DAEC): Current Insights and Future Challenges

PubMed Central

2014-01-01

SUMMARY The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as “silent pathogens” with the capacity to emerge as “pathobionts” for the development of inflammatory bowel disease and intestinal carcinogenesis. PMID:25278576

Teachers' Perspectives on Online Virtual Labs vs. Hands-On Labs in High School Science

NASA Astrophysics Data System (ADS)

Bohr, Teresa M.

This study of online science teachers' opinions addressed the use of virtual labs in online courses. A growing number of schools use virtual labs that must meet mandated laboratory standards to ensure they provide learning experiences comparable to hands-on labs, which are an integral part of science curricula. The purpose of this qualitative case study was to examine teachers' perceptions of the quality and effectiveness of high school virtual labs. The theoretical foundation was constructivism, as labs provide student-centered activities for problem solving, inquiry, and exploration of phenomena. The research questions focused on experienced teachers' perceptions of the quality of virtual vs. hands-on labs. Data were collected through survey questions derived from the lab objectives of The Next Generation Science Standards . Eighteen teachers rated the degree of importance of each objective and also rated how they felt virtual labs met these objectives; these ratings were reported using descriptive statistics. Responses to open-ended questions were few and served to illustrate the numerical results. Many teachers stated that virtual labs are valuable supplements but could not completely replace hands-on experiences. Studies on the quality and effectiveness of high school virtual labs are limited despite widespread use. Comprehensive studies will ensure that online students have equal access to quality labs. School districts need to define lab requirements, and colleges need to specify the lab experience they require. This study has potential to inspire positive social change by assisting science educators, including those in the local school district, in evaluating and selecting courseware designed to promote higher order thinking skills, real-world problem solving, and development of strong inquiry skills, thereby improving science instruction for all high school students.

CancerDR: cancer drug resistance database.

PubMed

Kumar, Rahul; Chaudhary, Kumardeep; Gupta, Sudheer; Singh, Harinder; Kumar, Shailesh; Gautam, Ankur; Kapoor, Pallavi; Raghava, Gajendra P S

2013-01-01

Cancer therapies are limited by the development of drug resistance, and mutations in drug targets is one of the main reasons for developing acquired resistance. The adequate knowledge of these mutations in drug targets would help to design effective personalized therapies. Keeping this in mind, we have developed a database "CancerDR", which provides information of 148 anti-cancer drugs, and their pharmacological profiling across 952 cancer cell lines. CancerDR provides comprehensive information about each drug target that includes; (i) sequence of natural variants, (ii) mutations, (iii) tertiary structure, and (iv) alignment profile of mutants/variants. A number of web-based tools have been integrated in CancerDR. This database will be very useful for identification of genetic alterations in genes encoding drug targets, and in turn the residues responsible for drug resistance. CancerDR allows user to identify promiscuous drug molecules that can kill wide range of cancer cells. CancerDR is freely accessible at http://crdd.osdd.net/raghava/cancerdr/

TangoLab-2 Card Troubleshooting

NASA Image and Video Library

2017-10-17

iss053e105442 (Oct. 17, 2017) --- Flight Engineer Mark Vande Hei swaps out a payload card from the TangoLab-1 facility and places into the TangoLab-2 facility. TangoLab provides a standardized platform and open architecture for experimental modules called CubeLabs. CubeLab modules may be developed for use in 3-dimensional tissue and cell cultures.

KSC-2012-2766

NASA Image and Video Library

2012-05-14

CAPE CANAVERAL, Fla. – Students view a demonstration by Dr. James Fesmire inside the cryogenics lab in the Operations and Checkout Building. The 26 honor students in chemistry and biology and their teachers got a chance to visit a number of high-tech labs at Kennedy Space Center as part of an effort to encourage students in the areas of science, technology, engineering and math. The tenth and eleventh grade students from Terry Parker High School in Jacksonville, Fla., visited a number of vastly different labs during their one-day tour. The group's visit to Kennedy was hosted by the Education Office as part of a nationwide effort by the National Lab Network to help introduce the nation's students to science careers. Photo credit: NASA/Jim Grossmann

The Earth is our lab: Ten years of geoscience school lab in Potsdam

NASA Astrophysics Data System (ADS)

Nikolaus Küppers, Andreas

2016-04-01

Starting in 2004, a geoscientific school lab for senior high school students was developed in the historical "Großer Refraktor" premises on the Telegraphenberg in Potsdam. Based on a one-day course architecture, laboratory days were developed covering singular themes: - Magnetic field of the Earth - Geographical Information Systems and geodata - Gravity field of the Earth - Geodynamics: seismology and seismics - Geoscience math - Geodata Brandenburg (Geological mapping with aerophotographs, remote sensing, underground data processing) With a focus on geophysical methodologies, course days generally focused on the field work around the Telegraphenberg site while introducing into the art of handling original professional equipment. Field data were afterwards compiled, analysed and interpreted in the group. Single days could be combined as clusters of up to one week and were bookable for national and international groups of max. 25 students. The courses were taught by active scientists with the assistance of student guides as the larger groups had to be split up. The paper gives an overview over the development history of the school lab and explains the course contents, the teaching methods and several employed escorting measures. Possible impact on the professional career decisions of the students is discussed.

Giant Electromagnet Move at Brookhaven Lab, June 22, 2013

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

2013-06-22

On Saturday, June 22, 2013, a 50-foot-wide, circular electromagnet began its 3,200-mile land and sea voyage from Brookhaven National Laboratory in New York to a new home at Fermilab in Illinois. There, scientists will use it to study the properties of muons, subatomic particles that live only 2.2 millionths of a second, and the results could open the door to new realms of particle physics. In the first part of the move, Emmert International and a team of Fermilab and Brookhaven Lab scientists and engineers transported the electromagnet across the Brookhaven Lab site to a staging area by its mainmore » gate.« less

Pathogenesis of human diffusely adhering Escherichia coli expressing Afa/Dr adhesins (Afa/Dr DAEC): current insights and future challenges.

PubMed

Servin, Alain L

2014-10-01

The pathogenicity and clinical pertinence of diffusely adhering Escherichia coli expressing the Afa/Dr adhesins (Afa/Dr DAEC) in urinary tract infections (UTIs) and pregnancy complications are well established. In contrast, the implication of intestinal Afa/Dr DAEC in diarrhea is still under debate. These strains are age dependently involved in diarrhea in children, are apparently not involved in diarrhea in adults, and can also be asymptomatic intestinal microbiota strains in children and adult. This comprehensive review analyzes the epidemiology and diagnosis and highlights recent progress which has improved the understanding of Afa/Dr DAEC pathogenesis. Here, I summarize the roles of Afa/Dr DAEC virulence factors, including Afa/Dr adhesins, flagella, Sat toxin, and pks island products, in the development of specific mechanisms of pathogenicity. In intestinal epithelial polarized cells, the Afa/Dr adhesins trigger cell membrane receptor clustering and activation of the linked cell signaling pathways, promote structural and functional cell lesions and injuries in intestinal barrier, induce proinflammatory responses, create angiogenesis, instigate epithelial-mesenchymal transition-like events, and lead to pks-dependent DNA damage. UTI-associated Afa/Dr DAEC strains, following adhesin-membrane receptor cell interactions and activation of associated lipid raft-dependent cell signaling pathways, internalize in a microtubule-dependent manner within urinary tract epithelial cells, develop a particular intracellular lifestyle, and trigger a toxin-dependent cell detachment. In response to Afa/Dr DAEC infection, the host epithelial cells generate antibacterial defense responses. Finally, I discuss a hypothetical role of intestinal Afa/Dr DAEC strains that can act as "silent pathogens" with the capacity to emerge as "pathobionts" for the development of inflammatory bowel disease and intestinal carcinogenesis. Copyright © 2014, American Society for Microbiology. All Rights

Dr. von Braun Briefing Walt Disney

NASA Technical Reports Server (NTRS)

1965-01-01

Dr. von Braun began his association with Walt Disney in the 1950s when the rocket scientist appeared in three Disney television productions related to the exploration of space. Years later, Dr. von Braun invited Disney and his associates to tour the Marshall Space Flight Center (MSFC) in Huntsville, Alabama. This photograph is dated April 13, 1965. From left are R.J. Schwinghamer from the MSFC, Disney, B.J. Bernight, and Dr. von Braun.

A comparative study on real lab and simulation lab in communication engineering from students' perspectives

NASA Astrophysics Data System (ADS)

Balakrishnan, B.; Woods, P. C.

2013-05-01

Over the years, rapid development in computer technology has engendered simulation-based laboratory (lab) in addition to the traditional hands-on (physical) lab. Many higher education institutions adopt simulation lab, replacing some existing physical lab experiments. The creation of new systems for conducting engineering lab activities has raised concerns among educators on the merits and shortcomings of both physical and simulation labs; at the same time, many arguments have been raised on the differences of both labs. Investigating the effectiveness of both labs is complicated, as there are multiple factors that should be considered. In view of this challenge, a study on students' perspectives on their experience related to key aspects on engineering laboratory exercise was conducted. In this study, the Visual Auditory Read and Kinetic model was utilised to measure the students' cognitive styles. The investigation was done through a survey among participants from Multimedia University, Malaysia. The findings revealed that there are significant differences for most of the aspects in physical and simulation labs.

Take a Trip Around a 3D Printing Lab (360)

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Additive manufacturing has changed the way the world thinks about manufacture and design. Scientists and researchers at Lawrence Livermore National Lab are using a number of 3D printing processes to experiment with unique combinations of plastic, metal, and ceramics.

A Constructivist Cloud Lab.

ERIC Educational Resources Information Center

Emery, Dave

1996-01-01

Describes a lab involving a cloud formation activity that uses the constructivist learning model to get students more involved in creating the lab. Enables students to develop a greater understanding of the concepts involved and more interest in the lab's outcomes. (JRH)

Virtual Reality Lab Assistant

NASA Technical Reports Server (NTRS)

Saha, Hrishikesh; Palmer, Timothy A.

1996-01-01

Virtual Reality Lab Assistant (VRLA) demonstration model is aligned for engineering and material science experiments to be performed by undergraduate and graduate students in the course as a pre-lab simulation experience. This will help students to get a preview of how to use the lab equipment and run experiments without using the lab hardware/software equipment. The quality of the time available for laboratory experiments can be significantly improved through the use of virtual reality technology.

LabSkills

ERIC Educational Resources Information Center

O'Brien, Nick

2010-01-01

This article describes LabSkills, a revolutionary teaching tool to improve practical science in schools. LabSkills offers the chance to help improve the exposure that the average Key Stage 5 (age 16-19) student has to practical work. This is a huge area for development being highlighted by universities who are seeing a worryingly growing trend in…

America's Lab Report: Investigations in High School Science

ERIC Educational Resources Information Center

Singer, Susan R., Ed.; Hilton, Margaret L., Ed.; Schweingruber, Heidi A., Ed.

2005-01-01

Laboratory experiences as a part of most U.S. high school science curricula have been taken for granted for decades, but they have rarely been carefully examined. What do they contribute to science learning? What can they contribute to science learning? What is the current status of labs in our nation s high schools as a context for learning…

PUB-3000 | BERKELEY LAB HEALTH AND SAFETY MANUAL

Science.gov Websites

ES&H MANUAL (PUB-3000) Berkeley Lab Table of Contents Guide to Using the ES&H Manual Responsible Authors Log of ES&H Manual Changes Requesting a Change to the ES&H Manual Search the ES &H Manual Questions & Comments Lawrence Berkeley National Laboratory University of California

hwhwap_Ep29_The National Lab in Space

NASA Image and Video Library

2018-01-26

[00:00:00] Gary Jordan (Host): Houston We Have a Podcast. Welcome to the official podcast of the NASA Johnson Space Center, Episode 29, The National Lab in Space. I'm Gary Jordan, and I'll be your host today. So this is the podcast where we bring in the experts, NASA scientists, engineers, astronauts, sometimes some of our partners. We bring them right here on the show to tell you all the cool stuff about what's going on here at NASA. So today we're talking about the section of the International Space Station that's designated as a U.S. national laboratory. We're talking with Patrick O'Neill, the marketing and communications manager at the Center for Advancement of Science in Space, or CASIS. We had a great discussion about what it means to be a U.S. national lab, how CASIS is bringing research from companies, research to institutions, and government agencies to the Space Station, and the things we're learning that benefit human kind. So with no further delay, let's go light speed and jump right ahead to our talk with Mr. Patrick O'Neill. Enjoy. [00:00:53] [ Music ] Host: All right, well, Patrick, thanks so much for taking the time to come on the podcast, especially because you are remote, right? You're not even here in Houston. You're calling in from Florida, right? [00:01:26] Patrick O’Neill: I am over at Kenney Space Center as we speak. [00:01:29] Host: Awesome. And that's where CASIS is sort of housed? Is that where you guys are? Or are you kind of all over the place? [00:01:36] Patrick O’Neill: Well, we actually have a couple of houses across the country. But yes, in theory, this is kind of where our headquarters is based out of in the Kenney Space Center area, as well as Melbourne, Florida. But we also have strong office presence just outside of Johnson Space Center in Houston, and then we have a few more offices that are sporadically placed throughout the country. [00:01:54] Host: Very cool. All right, so you're over at the Kenney Space Center, yeah

Dr. Wernher von Braun

NASA Technical Reports Server (NTRS)

2004-01-01

Dr. von Braun is looking out from a 10th floor window of building 4200 at the Marshall Space Flight Center (MSFC). He was the first Center Director and served as the Director from July 1960 through February 1970. Following World War II, Dr. von Braun and his German colleagues arrived in the United States under the Project Paperclip (American acquisition of German rocket experts) to continue their rocket development work. In 1950, von Braun and his German Rocket Team (also called the Peenemuende Team) were transferred from Ft. Bliss, Texas to Huntsville, Alabama to work for the Army's rocket program at Redstone Arsenal and later, NASA's Marshall Space Flight Center (MSFC). Under Dr. von Braun's leadership, MSFC developed the Saturn V launch vehicle, which placed the first men, two American astronauts, on the Moon. Wernher von Braun's life was dedicated to expanding man's knowledge through the exploration of space.

International treatment access and research, how you can help--interview with Dr. Peter Piot of UNAIDS. Joint United Nations Programme on HIV/AIDS. Interview by John S. James.

PubMed

Piot, P

1996-11-01

Medical advances in the United States have greatly increased the lifespan of people with AIDS, but there is no access to modern medicine for the 90 percent of AIDS patients who live in other countries. Dr. Peter Piot of the United Nations Programme on HIV/AIDS (UNAIDS) addresses the efforts of six U.N. agencies in improving treatment access throughout the world and improving research on natural and traditional medicines.

Small Particles in Cirrus (SPartICus) and Storm Peak Lab Validation Experiment (StormVEx) Science Final Technical Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mace, Gerald

The Small Particles in Cirrus (SPartICus) campaign took place from January through June, 2011 and the Storm Peak Lab Cloud Property Validation Experiment (StormVEx) took place from November, 2011 through April, 2012. The PI of this project, Dr. Gerald Mace, had the privilege to be the lead on both of these campaigns. The essence of the project that we report on here was to conduct preliminary work that was necessary to bring the field data sets to a point where they could be used for their intended science purposes

Current Issues in Teacher Education: An Interview with Dr. Linda Darling-Hammond

ERIC Educational Resources Information Center

Martin, Linda E.; Mulvihill, Thalia M.

2017-01-01

Dr. Linda Darling-Hammond is the Charles E. Ducommun Professor of Education Emeritus at the Stanford Graduate School of Education at Stanford University. She is former president of the American Educational Research Association (AERA) and member of the National Academy of Education and the American Academy of Arts and Sciences. She also served as a…

Dr. Robert H. Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Hutchings Goddard (1882-1945). Dr. Goddard has been recognized as the father of American rocketry and as one of the pioneers in the theoretical exploration of space. Robert Hutchings Goddard, born in Worcester, Massachusetts, on October 5, 1882, was theoretical scientist as well as a practical engineer. His dream was the conquest of the upper atmosphere and ultimately space through the use of rocket propulsion. Dr. Goddard, died in 1945, but was probably as responsible for the dawning of the Space Age as the Wrights were for the beginning of the Air Age. Yet his work attracted little serious attention during his lifetime. However, when the United States began to prepare for the conquest of space in the 1950's, American rocket scientists began to recognize the debt owed to the New England professor. They discovered that it was virtually impossible to construct a rocket or launch a satellite without acknowledging the work of Dr. Goddard. More than 200 patents, many of which were issued after his death, covered this great legacy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

KSC-2012-2764

NASA Image and Video Library

2012-05-14

CAPE CANAVERAL, Fla. – Dr. Ray Wheeler explains a system for growing salad crops in space to students in the Life Support and Habitation Systems Lab at the Space Life Sciences Lab facility. The 26 honor students in chemistry and biology and their teachers got a chance to visit a number of high-tech labs at Kennedy Space Center as part of an effort to encourage students in the areas of science, technology, engineering and math. The tenth and eleventh grade students from Terry Parker High School in Jacksonville, Fla., visited a number of vastly different labs during their one-day tour. The group's visit to Kennedy was hosted by the Education Office as part of a nationwide effort by the National Lab Network to help introduce the nation's students to science careers. Photo credit: NASA/Jim Grossmann

KSC-2012-2761

NASA Image and Video Library

2012-05-14

CAPE CANAVERAL, Fla. – Dr. Phil Metzger demonstrates an experiment to study the physics of granular materials to students in the Granular Physics and Regolith Operations Lab at the Space Life Sciences Lab facility. The 26 honor students in chemistry and biology and their teachers got a chance to visit a number of high-tech labs at Kennedy Space Center as part of an effort to encourage students in the areas of science, technology, engineering and math. The tenth and eleventh grade students from Terry Parker High School in Jacksonville, Fla., visited a number of vastly different labs during their one-day tour. The group's visit to Kennedy was hosted by the Education Office as part of a nationwide effort by the National Lab Network to help introduce the nation's students to science careers. Photo credit: NASA/Jim Grossmann

KSC-2012-2763

NASA Image and Video Library

2012-05-14

CAPE CANAVERAL, Fla. – Dr. Ray Wheeler explains a system for growing salad crops in space to students in the Life Support and Habitation Systems Lab at the Space Life Sciences Lab facility. The 26 honor students in chemistry and biology and their teachers got a chance to visit a number of high-tech labs at Kennedy Space Center as part of an effort to encourage students in the areas of science, technology, engineering and math. The tenth and eleventh grade students from Terry Parker High School in Jacksonville, Fla., visited a number of vastly different labs during their one-day tour. The group's visit to Kennedy was hosted by the Education Office as part of a nationwide effort by the National Lab Network to help introduce the nation's students to science careers. Photo credit: NASA/Jim Grossmann

NHEXAS PHASE I ARIZONA STUDY--STANDARD OPERATING PROCEDURE FOR CODING: ARIZONA LAB DATA (UA-D-13.0)

EPA Science Inventory

The purpose of this SOP is to define the coding strategy for Arizona Lab Data. This strategy was developed for use in the Arizona NHEXAS project and the "Border" study. Keywords: data; coding; lab data forms.

The National Human Exposure Assessment Survey (NHEXAS) is a federal ...

Boosting Big National Lab Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kleese van Dam, Kerstin

Introduction: Big data. Love it or hate it, solving the world’s most intractable problems requires the ability to make sense of huge and complex sets of data and do it quickly. Speeding up the process – from hours to minutes or from weeks to days – is key to our success. One major source of such big data are physical experiments. As many will know, these physical experiments are commonly used to solve challenges in fields such as energy security, manufacturing, medicine, pharmacology, environmental protection and national security. Experiments use different instruments and sensor types to research for example themore » validity of new drugs, the base cause for diseases, more efficient energy sources, new materials for every day goods, effective methods for environmental cleanup, the optimal ingredients composition for chocolate or determine how to preserve valuable antics. This is done by experimentally determining the structure, properties and processes that govern biological systems, chemical processes and materials. The speed and quality at which we can acquire new insights from experiments directly influences the rate of scientific progress, industrial innovation and competitiveness. And gaining new groundbreaking insights, faster, is key to the economic success of our nations. Recent years have seen incredible advances in sensor technologies, from house size detector systems in large experiments such as the Large Hadron Collider and the ‘Eye of Gaia’ billion pixel camera detector to high throughput genome sequencing. These developments have led to an exponential increase in data volumes, rates and variety produced by instruments used for experimental work. This increase is coinciding with a need to analyze the experimental results at the time they are collected. This speed is required to optimize the data taking and quality, and also to enable new adaptive experiments, where the sample is manipulated as it is observed, e.g. a substance is injected

Sustainable dual-use labs: neurovascular interventional capabilities within the cath lab.

PubMed

Lang, Stacey

2012-01-01

The inclusion of neurovascular interventional capabilities within the cath lab setting can be key to optimal utilization of resources, increased staff efficiency, and streamlined operations. When considering an expansion, look beyond the patient population traditionally associated with cardiac cath labs and consider the integration of programs outside cardiac alone--to create a true dual-use lab space. With proper planning, quality dual purpose equipment, appropriately trained staff, capable physicians, and strong leadership, an organization willing to embrace the challenge can build a truly extraordinary service.

Maniac Talk - Dr. Marshall Shepherd

NASA Image and Video Library

2015-07-14

Marshall Shepherd Maniac Lecture, July 14, 2015 Dr. Marshall Shepherd, professor, University of Georgia, also the host of Sunday's talk show Weather Geeks, presented a Maniac lecture entitled "Zombies, Sports, and Cola: Implications for Communicating Weather and Climate." Believe it or not, Dr. Shepherd ties zombies, sports, and cola together to provide a compelling look at how we communicate (miscommunicate) weather and climate.

Lab at Home: Hardware Kits for a Digital Design Lab

ERIC Educational Resources Information Center

Oliver, J. P.; Haim, F.

2009-01-01

An innovative laboratory methodology for an introductory digital design course is presented. Instead of having traditional lab experiences, where students have to come to school classrooms, a "lab at home" concept is proposed. Students perform real experiments in their own homes, using hardware kits specially developed for this purpose. They…

RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis.

PubMed

Brünker, Peter; Wartha, Katharina; Friess, Thomas; Grau-Richards, Sandra; Waldhauer, Inja; Koller, Claudia Ferrara; Weiser, Barbara; Majety, Meher; Runza, Valeria; Niu, Huifeng; Packman, Kathryn; Feng, Ningping; Daouti, Sherif; Hosse, Ralf J; Mössner, Ekkehard; Weber, Thomas G; Herting, Frank; Scheuer, Werner; Sade, Hadassah; Shao, Cuiying; Liu, Bin; Wang, Peng; Xu, Gary; Vega-Harring, Suzana; Klein, Christian; Bosslet, Klaus; Umaña, Pablo

2016-05-01

Dysregulated cellular apoptosis and resistance to cell death are hallmarks of neoplastic initiation and disease progression. Therefore, the development of agents that overcome apoptosis dysregulation in tumor cells is an attractive therapeutic approach. Activation of the extrinsic apoptotic pathway is strongly dependent on death receptor (DR) hyperclustering on the cell surface. However, strategies to activate DR5 or DR4 through agonistic antibodies have had only limited clinical success. To pursue an alternative approach for tumor-targeted induction of apoptosis, we engineered a bispecific antibody (BsAb), which simultaneously targets fibroblast-activation protein (FAP) on cancer-associated fibroblasts in tumor stroma and DR5 on tumor cells. We hypothesized that bivalent binding to both FAP and DR5 leads to avidity-driven hyperclustering of DR5 and subsequently strong induction of apoptosis in tumor cells but not in normal cells. Here, we show that RG7386, an optimized FAP-DR5 BsAb, triggers potent tumor cell apoptosis in vitro and in vivo in preclinical tumor models with FAP-positive stroma. RG7386 antitumor efficacy was strictly FAP dependent, was independent of FcR cross-linking, and was superior to conventional DR5 antibodies. In combination with irinotecan or doxorubicin, FAP-DR5 treatment resulted in substantial tumor regression in patient-derived xenograft models. FAP-DR5 also demonstrated single-agent activity against FAP-expressing malignant cells, due to cross-binding of FAP and DR5 across tumor cells. Taken together, these data demonstrate that RG7386, a novel and potent antitumor agent in both mono- and combination therapies, overcomes limitations of previous DR5 antibodies and represents a promising approach to conquer tumor-associated resistance to apoptosis. Mol Cancer Ther; 15(5); 946-57. ©2016 AACR. ©2016 American Association for Cancer Research.

Dr. von Braun and Dr. Stuhlinger With a Model of the Nuclear-Electric Vehicles

NASA Technical Reports Server (NTRS)

2004-01-01

In this photo, taken at the Walt Disney Studios in California, Dr. Wernher von Braun and Dr. Ernst Stuhlinger are shown discussing the concepts of nuclear-electric spaceships designed to undertake the mission to the planet Mars. As a part of the Disney 'Tomorrowland' series on the exploration of space, the nuclear-electric vehicles were shown in the last three television films, entitled 'Mars and Beyond,' which first aired in December 1957.

LCOGT Imaging Lab

NASA Astrophysics Data System (ADS)

Tufts, Joseph R.; Lobdill, Rich; Haldeman, Benjamin J.; Haynes, Rachel; Hawkins, Eric; Burleson, Ben; Jahng, David

2008-07-01

The Las Cumbres Observatory Global Telescope Network (LCOGT) is an ambitious project to build and operate, within 5 years, a worldwide robotic network of 50 0.4, 1, and 2 m telescopes sharing identical instrumentation and optimized for precision photometry of time-varying sources. The telescopes, instrumentation, and software are all developed in house with two 2 m telescopes already installed. The LCOGT Imaging Lab is responsible for assembly and characterization of the network's cameras and instrumentation. In addition to a fully equipped CNC machine shop, two electronics labs, and a future optics lab, the Imaging Lab is designed from the ground up to be a superb environment for bare detectors, precision filters, and assembled instruments. At the heart of the lab is an ISO class 5 cleanroom with full ionization. Surrounding this, the class 7 main lab houses equipment for detector characterization including QE and CTE, and equipment for measuring transmission and reflection of optics. Although the first science cameras installed, two TEC cooled e2v 42-40 deep depletion based units and two CryoTiger cooled Fairchild Imaging CCD486-BI based units, are from outside manufacturers, their 18 position filter wheels and the remainder of the network's science cameras, controllers, and instrumentation will be built in house. Currently being designed, the first generation LCOGT cameras for the network's 1 m telescopes use existing CCD486-BI devices and an in-house controller. Additionally, the controller uses digital signal processing to optimize readout noise vs. speed, and all instrumentation uses embedded microprocessors for communication over ethernet.

Inexpensive DAQ based physics labs

NASA Astrophysics Data System (ADS)

Lewis, Benjamin; Clark, Shane

2015-11-01

Quality Data Acquisition (DAQ) based physics labs can be designed using microcontrollers and very low cost sensors with minimal lab equipment. A prototype device with several sensors and documentation for a number of DAQ-based labs is showcased. The device connects to a computer through Bluetooth and uses a simple interface to control the DAQ and display real time graphs, storing the data in .txt and .xls formats. A full device including a larger number of sensors combined with software interface and detailed documentation would provide a high quality physics lab education for minimal cost, for instance in high schools lacking lab equipment or students taking online classes. An entire semester’s lab course could be conducted using a single device with a manufacturing cost of under $20.

ORAC-DR -- SCUBA Pipeline Data Reduction

NASA Astrophysics Data System (ADS)

Jenness, Tim; Economou, Frossie

ORAC-DR is a flexible data reduction pipeline designed to reduce data from many different instruments. This document describes how to use the ORAC-DR pipeline to reduce data taken with the Submillimetre Common-User Bolometer Array (SCUBA) obtained from the James Clerk Maxwell Telescope.

MatLab Script and Functional Programming

NASA Technical Reports Server (NTRS)

Shaykhian, Gholam Ali

2007-01-01

MatLab Script and Functional Programming: MatLab is one of the most widely used very high level programming languages for scientific and engineering computations. It is very user-friendly and needs practically no formal programming knowledge. Presented here are MatLab programming aspects and not just the MatLab commands for scientists and engineers who do not have formal programming training and also have no significant time to spare for learning programming to solve their real world problems. Specifically provided are programs for visualization. The MatLab seminar covers the functional and script programming aspect of MatLab language. Specific expectations are: a) Recognize MatLab commands, script and function. b) Create, and run a MatLab function. c) Read, recognize, and describe MatLab syntax. d) Recognize decisions, loops and matrix operators. e) Evaluate scope among multiple files, and multiple functions within a file. f) Declare, define and use scalar variables, vectors and matrices.

360 Video Tour of 3D Printing Labs at LLNL

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

Additive manufacturing is changing the way the world thinks about manufacturing and design. And here at Lawrence Livermore National Laboratory, it’s changing the way our scientists approach research and development. Today we’ll look around three of the additive manufacturing research labs on the Lawrence Livermore campus.

PRESIDENT KENNEDY TOURS CAPE CANAVERAL FACILITIES WITH DR. KURT H. DEBUS

NASA Technical Reports Server (NTRS)

1962-01-01

President Kennedy and Dr. Kurt Debus head for the car that will take them on a tour of our Nation's space facilities. The President, Vice President, and the Space Committee are among those being briefed at four locations on our space program. The tour includes Marshall Space Flight Center at Huntsville, Alabama, Atlantic Missile Range, Manned Space Flight Center, Houston, Texas, and McDonnell Aircraft at St. Louis, Mo.

Experiences with lab-centric instruction

NASA Astrophysics Data System (ADS)

Titterton, Nathaniel; Lewis, Colleen M.; Clancy, Michael J.

2010-06-01

Lab-centric instruction emphasizes supervised, hands-on activities by substituting lab for lecture time. It combines a multitude of pedagogical techniques into the format of an extended, structured closed lab. We discuss the range of benefits for students, including increased staff interaction, frequent and varied self-assessments, integrated collaborative activities, and a systematic sequence of activities that gradually increases in difficulty. Instructors also benefit from a deeper window into student progress and understanding. We follow with discussion of our experiences in courses at U.C. Berkeley, and using data from some of these investigate the effects of lab-centric instruction on student learning, procrastination, and course pacing. We observe that the lab-centric format helped students on exams but hurt them on extended programming assignments, counter to our hypothesis. Additionally, we see no difference in self-ratings of procrastination and limited differences in ratings of course pace. We do find evidence that the students who choose to attend lab-centric courses are different in several important ways from students who choose to attend the same course in a non-lab-centric format.

Improving the Quality of Lab Reports by Using Them as Lab Instructions

NASA Astrophysics Data System (ADS)

Haagen-Schuetzenhoefer, Claudia

2012-10-01

Lab exercises are quite popular in teaching science. Teachers have numerous goals in mind when teaching science laboratories. Nevertheless, empirical research draws a heterogeneous picture of the benefits of lab work. Research has shown that it does not necessarily contribute to the enhancement of practical abilities or content knowledge. Lab activities are frequently based on recipe-like, step-by-step instructions ("cookbook style"), which do not motivate students to engage cognitively. Consequently, students put the emphasis on "task completion" or "manipulating equipment."2

Understanding anthocyanin: Researcher and educator Dr. Ron Wrolstad

USDA-ARS?s Scientific Manuscript database

This invited presentation is in honor of Dr. Ronald E. Wrolstad (Distinguished Professor Emeritus), recipient of the 2017 ACS AGFD Advancement of the Application of Agricultural and Food Chemistry Award. The talk will be a brief overview of Dr. Ronald E. Wrolstad’s research program and career; Dr. W...

Insights: Future of the national laboratories. National Renewable Energy Laboratory. [The future of the National Renewable Energy (Sources) Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sunderman, D.

Psychologists tell us that people are born with certain personality traits, such as shyness or boldness, which their environment can encourage, subdue, or even alter. National labs have somewhat similar characteristics. They were created for particular missions and staffed by people who built organizations in which those missions could be fulfilled. As a result, the Department of Energy's (DOE) national labs are among the world's finest repositories of technology and scientific talent, especially in the fields of defense, nuclear weapons, nuclear power, and basic energy. Sunderman, director of the National Renewable Energy Laboratory, discusses the history of the laboratory andmore » its place in the future, both in terms of technologies and nurturing.« less

Optimal Design of a Two-Layered Elastic Strip Subjected to Transient Loading

DTIC Science & Technology

2005-05-01

M.J., 1999. GLO––global local optimizer users manual. Report UCRL -MA-133858, Energetic Materials Center, Lawrence Livermore National Laboratory...3 DARPA L CHRISTODOULOU W COBLENZ S WAX 3701 N FAIRFAX DR ARLINGTON VA 22203-1714 1 DIRECTOR US ARMY RESEARCH LAB AMSRL CS

Lab Report Blues

ERIC Educational Resources Information Center

Diaz, Andrew

2004-01-01

For middle school students, writing a formal lab report can be challenging. For middle level teachers, reading students lab reports can be overwhelming. After grading report after report with incomplete procedures, incorrect graphs, and missing conclusions, the author's frustration level was at an all-time high. Ready to try anything, he thought,…

Reforming Cookbook Labs

ERIC Educational Resources Information Center

Peters, Erin

2005-01-01

Deconstructing cookbook labs to require the students to be more thoughtful could break down perceived teacher barriers to inquiry learning. Simple steps that remove or disrupt the direct transfer of step-by-step procedures in cookbook labs make students think more critically about their process. Through trials in the author's middle school…

Dr. Francis Collins Is New NIH Director

MedlinePlus

... Current Issue Past Issues Dr. Francis Collins Is New NIH Director Past Issues / Summer 2009 Table of ... of this page please turn Javascript on. The new NIH Director, Dr. Francis Collins, served as Director ...

EarthLabs Modules: Engaging Students In Extended, Rigorous Investigations Of The Ocean, Climate and Weather

NASA Astrophysics Data System (ADS)

Manley, J.; Chegwidden, D.; Mote, A. S.; Ledley, T. S.; Lynds, S. E.; Haddad, N.; Ellins, K.

2016-02-01

EarthLabs, envisioned as a national model for high school Earth or Environmental Science lab courses, is adaptable for both undergraduate middle school students. The collection includes ten online modules that combine to feature a global view of our planet as a dynamic, interconnected system, by engaging learners in extended investigations. EarthLabs support state and national guidelines, including the NGSS, for science content. Four modules directly guide students to discover vital aspects of the oceans while five other modules incorporate ocean sciences in order to complete an understanding of Earth's climate system. Students gain a broad perspective on the key role oceans play in fishing industry, droughts, coral reefs, hurricanes, the carbon cycle, as well as life on land and in the seas to drive our changing climate by interacting with scientific research data, manipulating satellite imagery, numerical data, computer visualizations, experiments, and video tutorials. Students explore Earth system processes and build quantitative skills that enable them to objectively evaluate scientific findings for themselves as they move through ordered sequences that guide the learning. As a robust collection, EarthLabs modules engage students in extended, rigorous investigations allowing a deeper understanding of the ocean, climate and weather. This presentation provides an overview of the ten curriculum modules that comprise the EarthLabs collection developed by TERC and found at http://serc.carleton.edu/earthlabs/index.html. Evaluation data on the effectiveness and use in secondary education classrooms will be summarized.

DR Reactor VSR channel damage

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kempf, F.J.; Rawlins, J.K.

1961-10-30

On July 11, 1961 the Ball 3X System at DR Reactor was inadventently tripped. All vertical safety rods dropped and all channels were filled with balls. This report has the twofold purpose of documenting borescope observations of ten vertical rod channels at DR Reactor and recording the estimated extent of graphite damage resulting from the above incident. Channel damage data are presented on appended drawings. With suitable notations, the tracings of these drawings may be revised to reflect any future graphite damage. All vertical rod channels at DR Reactor were visually examined with a closed circuit television system during ballmore » removal efforts. Typical photographs of trapped balls and ledges, as viewed on the television monitor, are shown. Photographs of typical graphite damage, obtained through the borescope are also included in this report. 3 refs., 8 figs., 1 tab.« less

KSC-2012-2760

NASA Image and Video Library

2012-05-14

CAPE CANAVERAL, Fla. – Dr. LaNetra C. Tate, center, materials engineer at Kennedy Space Center, is surrounded by students as she welcomes them for their tour of the Space Life Sciences Lab facilities. The 26 honor students in chemistry and biology and their teachers got a chance to visit a number of high-tech labs at Kennedy as part of an effort to encourage students in the areas of science, technology, engineering and math. The tenth and eleventh grade students from Terry Parker High School in Jacksonville, Fla., visited a number of vastly different labs during their one-day tour. The group's visit to Kennedy was hosted by the Education Office as part of a nationwide effort by the National Lab Network to help introduce the nation's students to science careers. Photo credit: NASA/Jim Grossmann

About the Frederick National Laboratory for Cancer Research | FNLCR Staging

Cancer.gov

The Frederick National Lab is a Federally Funded Research and Development Center (FFRDC) sponsored by the National Cancer Institute (NCI) and operated by Leidos Biomedical Research, Inc. The lab addresses some of the most urgent and intractable probl

Status of chemistry lab safety in Nepal.

PubMed

Kandel, Krishna Prasad; Neupane, Bhanu Bhakta; Giri, Basant

2017-01-01

Chemistry labs can become a dangerous environment for students as the lab exercises involve hazardous chemicals, glassware, and equipment. Approximately one hundred thousand students take chemistry laboratory classes annually in Nepal. We conducted a survey on chemical lab safety issues across Nepal. In this paper, we assess the safety policy and equipment, protocols and procedures followed, and waste disposal in chemistry teaching labs. Significant population of the respondents believed that there is no monitoring of the lab safety in their lab (p<0.001). Even though many labs do not allow food and beverages inside lab and have first aid kits, they lack some basic safety equipment. There is no institutional mechanism to dispose lab waste and chemical waste is disposed haphazardly. Majority of the respondents believed that the safety training should be a part of educational training (p = 0.001) and they would benefit from short course and/or workshop on lab safety (p<0.001).

Status of chemistry lab safety in Nepal

PubMed Central

Kandel, Krishna Prasad; Neupane, Bhanu Bhakta

2017-01-01

Chemistry labs can become a dangerous environment for students as the lab exercises involve hazardous chemicals, glassware, and equipment. Approximately one hundred thousand students take chemistry laboratory classes annually in Nepal. We conducted a survey on chemical lab safety issues across Nepal. In this paper, we assess the safety policy and equipment, protocols and procedures followed, and waste disposal in chemistry teaching labs. Significant population of the respondents believed that there is no monitoring of the lab safety in their lab (p<0.001). Even though many labs do not allow food and beverages inside lab and have first aid kits, they lack some basic safety equipment. There is no institutional mechanism to dispose lab waste and chemical waste is disposed haphazardly. Majority of the respondents believed that the safety training should be a part of educational training (p = 0.001) and they would benefit from short course and/or workshop on lab safety (p<0.001). PMID:28644869

360 Video Tour of 3D Printing Labs at LLNL

ScienceCinema

None

2018-01-16

Additive manufacturing is changing the way the world thinks about manufacturing and design. And here at Lawrence Livermore National Laboratory, it’s changing the way our scientists approach research and development. Today we’ll look around three of the additive manufacturing research labs on the Lawrence Livermore campus.

The Newest Monument: The Martin Luther King, Jr. National Memorial

ERIC Educational Resources Information Center

Social Studies and the Young Learner, 2011

2011-01-01

This article features the newest monument, the Martin Luther King, Jr. National Memorial. The memorial on the National Mall in Washington, D.C., honoring Dr. Martin Luther King, Jr. will be an engaging landscape experience to convey four fundamental and recurring themes throughout Dr. King's life--democracy, justice, hope, and love. Natural…

ORAC-DR -- SCUBA-2 Pipeline Data Reduction

NASA Astrophysics Data System (ADS)

Gibb, Andrew G.; Jenness, Tim

The ORAC-DR data reduction pipeline is designed to reduce data from many different instruments. This document describes how to use ORAC-DR to process data taken with the SCUBA-2 instrument on the James Clerk Maxwell Telescope.

SenseLab

PubMed Central

Crasto, Chiquito J.; Marenco, Luis N.; Liu, Nian; Morse, Thomas M.; Cheung, Kei-Hoi; Lai, Peter C.; Bahl, Gautam; Masiar, Peter; Lam, Hugo Y.K.; Lim, Ernest; Chen, Huajin; Nadkarni, Prakash; Migliore, Michele; Miller, Perry L.; Shepherd, Gordon M.

2009-01-01

This article presents the latest developments in neuroscience information dissemination through the SenseLab suite of databases: NeuronDB, CellPropDB, ORDB, OdorDB, OdorMapDB, ModelDB and BrainPharm. These databases include information related to: (i) neuronal membrane properties and neuronal models, and (ii) genetics, genomics, proteomics and imaging studies of the olfactory system. We describe here: the new features for each database, the evolution of SenseLab’s unifying database architecture and instances of SenseLab database interoperation with other neuroscience online resources. PMID:17510162

Dr. Karol de Beaurain - a psychiatrist's profile. Part 2.

PubMed

Rutkowski, Krzysztof; Dembińska, Edyta

2017-06-18

The paper sets out to recall the profile of Karol de Beaurain, a psychiatrist, who was one of first Poles to use the psychoanalytic method in treatment. So far, he has been mostly known as the one who was Witkacy's psychoanalyst. Stanisław Ignacy Witkiewicz and Eugenia Dunin-Borkowska are the first patients who are known by their names and who received psychoanalytic treatment in the history of the Polish medicine. Stanisław Ignacy Witkiewicz's letters and drawings originating from the psychoanalysis period served as a source of information about Witkacy's psychoanalysis. The paper illustrates dr Beaurain's fate during World War I when he was first a military doctor in Skoczów and then an assistant in prof. Piltz's Neurological-Psychiatric Clinic in Kraków where he actively participated in the creation of a multidimensional programme of war neurosis treatment. After the war finished, initially Beaurain stayed at his assistant post at the Psychiatric Clinic in Kraków but then in 1921 he relocated to the National Psychiatric Hospital in Dziekanka near Poznań. With his professional expertise he contributed to the strengthening of the Great Poland region psychiatry that had experienced qualified personnel shortages after the German qualified staff left. The growing numbers of patients and the overload of professional duties were probably the factors that led to dr. Beaurain's premature death while he was holding the position of the head physician at the National Psychiatric Hospital in Owińska in February 1927.

Integrating Robotic Observatories into Astronomy Labs

NASA Astrophysics Data System (ADS)

Ruch, Gerald T.

2015-01-01

The University of St. Thomas (UST) and a consortium of five local schools is using the UST Robotic Observatory, housing a 17' telescope, to develop labs and image processing tools that allow easy integration of observational labs into existing introductory astronomy curriculum. Our lab design removes the burden of equipment ownership by sharing access to a common resource and removes the burden of data processing by automating processing tasks that are not relevant to the learning objectives.Each laboratory exercise takes place over two lab periods. During period one, students design and submit observation requests via the lab website. Between periods, the telescope automatically acquires the data and our image processing pipeline produces data ready for student analysis. During period two, the students retrieve their data from the website and perform the analysis. The first lab, 'Weighing Jupiter,' was successfully implemented at UST and several of our partner schools. We are currently developing a second lab to measure the age of and distance to a globular cluster.

SPHERES National Lab Facility

NASA Technical Reports Server (NTRS)

Benavides, Jose

2014-01-01

SPHERES is a facility of the ISS National Laboratory with three IVA nano-satellites designed and delivered by MIT to research estimation, control, and autonomy algorithms. Since Fall 2010, The SPHERES system is now operationally supported and managed by NASA Ames Research Center (ARC). A SPHERES Program Office was established and is located at NASA Ames Research Center. The SPHERES Program Office coordinates all SPHERES related research and STEM activities on-board the International Space Station (ISS), as well as, current and future payload development. By working aboard ISS under crew supervision, it provides a risk tolerant Test-bed Environment for Distributed Satellite Free-flying Control Algorithms. If anything goes wrong, reset and try again! NASA has made the capability available to other U.S. government agencies, schools, commercial companies and students to expand the pool of ideas for how to test and use these bowling ball-sized droids. For many of the researchers, SPHERES offers the only opportunity to do affordable on-orbit characterization of their technology in the microgravity environment. Future utilization of SPHERES as a facility will grow its capabilities as a platform for science, technology development, and education.

Dr. Irene Sänger-Bredt, a life for astronautics

NASA Astrophysics Data System (ADS)

Zaganescu, Nicolae-Florin

2004-12-01

Irene Bredt (b.1911 at Bonn) obtained her Doctorate in Physics in 1937; in the same year she became a scientific researcher at the German Research Center for Aviation at Trauen, led by Prof. Dr. Eugen Sänger. Soon, the young but efficient Dr. Irene Bredt became the first assistant of Dr. Sänger, who married her (1951). During 1973-1978, Dr. Bredt was in correspondence with Prof. Dr. Nikolae-Florin Zaganescu and helped him to familiarize the Romanian readers with Prof. Sänger's life and achievements. As for Dr. Bredt's life, she specified three main periods of her activity: 1937-1942, when she was researcher in charge of thermodynamic problems of liquid-fuelled rocket engines at Trauen 1942-1945, when she was Senior Researcher in charge of Ramjet in flight performances at Ainring, and also coauthored the Top Secret Technical report entitled 'A Rocket Engine for a Long-Range Bomber', which was finished in 1941 but edited only in 1944 the post world war II period, when she was Scientific Advisor or Director at various civil and military research institutes, universities, etc. Dr. Irene Sänger-Bredt helped her husband to develop many scientific theories like Ramjet thermodynamic theory, and photon rocket theory and also in establishing IAF and IAA. In 1970, Dr. Irene Sänger-Bredt was honored with 'Hermann Oberth Gold Medal' for her impressive scientific activity.

Dr. Andrew Foster: A Literature Review.

PubMed

Runnels, Joel

2017-01-01

Often compared to Laurent Clerc, Thomas Gallaudet, and Alexander Graham Bell, Dr. Andrew Foster was a deaf African American who founded 32 schools for the deaf in 13 African nations. The 60th anniversary of his arrival in Liberia and Ghana and the 30th anniversary of his tragic death in a Rwanda airplane accident both occur in 2017. Renewed interest in Foster has spawned research and events to reexamine questions about his contributions to the expansion of deaf education in Africa. However, none of these activities have taken a full biographical approach. More in-depth, historical, and biographical research is needed to answer the many remaining questions about Foster's life and legacy. A literature review was conducted to investigate what are considered Foster's key contributions and the factors that might have motivated him to expand access to deaf education in Africa.

Goldie Brangman Remembers the Operation to Save Dr King.

PubMed

Koch, Evan; Brangman, Goldie

2015-12-01

In September 1958 the Rev Dr Martin Luther King Jr was stabbed and nearly assassinated. Surgeons at Harlem Hospital in New York City removed a 17.8-cm (7-in)-long letter opener from Dr King's chest. Certified Registered Nurse Anesthetist Goldie Brangman remembers this event because she participated in Dr King's anesthetic. This article correlates Brangman's memories with published accounts of the event. It also places the event within the context of the modern civil rights movement that Dr King led.

Dr. Goddard and a 1918 version of 'Bazooka'

NASA Technical Reports Server (NTRS)

2004-01-01

Dr. Robert H. Goddard loading a 1918 version of the Bazooka of World War II. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets, which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

Tour Brookhaven Lab's Future Hub for Energy Research: The Interdisciplinary Science Building

ScienceCinema

Gerry Stokes; Jim Misewich; Caradonna, Peggy; Sullivan, John; Olsen, Jim

2018-04-16

Construction is under way for the Interdisciplinary Science Building (ISB), a future world-class facility for energy research at Brookhaven Lab. Meet two scientists who will develop solutions at the ISB to tackle some of the nation's energy challenges, and tour the construction site.

Integrated Disinfection By-Products Mixtures Research: Results from the Four Lab Study

EPA Science Inventory

This study involves collaboration of four national laboratories/centers of the U.S. Environmental Protection Agency (EPA), as well as scientists from universities and water utilities, and is termed the ‘Four Lab Study’. The purpose of this study is to address concerns related to...

Smartphones - the Geophysics Lab in Your Students' Pocket

NASA Astrophysics Data System (ADS)

Salaree, A.; Stein, S.; Saloor, N.; Elling, R. P.

2017-12-01

Many interesting topics are hard to demonstrate in geophysics classes without costly equipment and logistic hassles. For instance, the speed of P-waves in the Earth's crust is usually calculated using printed seismic sections from published studies, giving students little insight into the recording process. This is mainly due to the complex, costly, and weather-dependent logistics of conducting seismic reflection experiments using arrays of - either purchased or borrowed - expensive seismometers and recording units. Smartphones, which students own and are (perhaps unduly) comfortable with, have many otherwise expensive instruments as built-in sensors. These instruments are nifty tools that make labs easier, faster, and more fun. We use smartphones in several labs in an introductory geophysics class. In one, students use their phones to measure the latitude and longitude of a point on campus. Combining the data shows a nice spread of positions illustrating the precision of measurements, spatial trends in the scatter, and even differences between Android and iPhone data. Hence concepts about data that are often presented with ideal theoretical examples emerge from the students' measurements. Another uses the phones' accelerometers and available software to measure the speed of P-waves using a linear array of smartphones/seismometers along a table, similar to the procedure used in reflection seismology. In a third, students used their smartphones in an elevator to measure the acceleration of gravity in a moving reference frame, and thus explore key concepts that arise in many geophysical applications. These three applications illustrate the potential for using smartphones in a wide variety of geophysics teaching, much as their value is being increasingly recognized in other educational applications. Here are some links to an instructions document and a video from the seismic experiment: Instructions: http://www.earth.northwestern.edu/ amir/202/smartphone

Differential workload calculation and its impact on lab science instruction at the community college level

NASA Astrophysics Data System (ADS)

Boyd, Beth Nichols

The calculation of workload for science instructors who teach classes with laboratory components at the community college level is inconsistent. Despite recommendations from the National Research Council (1996) and the large body of evidence which indicates that activity-based instruction produces greater learning gains than passive, lecture-based instruction, many community colleges assign less value to the time spent in science lab than in lecture in workload calculations. This discrepancy is inconsistent with both current state and nation-wide goals of science excellence and the standards set by the American Chemical Society (2009) and the American Association of Physics Teachers (2002). One implication of this differential lab-loading policy is that the science instructors must teach more hours per week to make the same workload as their colleagues in other disciplines which have no formal laboratory activities. Prior to this study, there was no aggregate data regarding the extent of this policy at the community college level nor of its possible impact upon instruction. The input of full-time two-year college members of four different professional science organizations was solicited and from their responses, it is clear that differential loading of lab hours is common and widely variable. A majority of the respondents to this study had their hours in lab assigned less credit than their hours in lecture, with multiple perceived impacts upon lab preparation, assistance, revision, and follow-up activities. In combination with open-ended comments made by study participants, the results suggest that science instructors do perceive impacts upon their ability to teach science labs in a pedagogically current and challenging manner when their hours spent in lab instruction are counted for less than their hours in lecture. It is hoped that the information from this study will be used to implement improvements in the working conditions needed to advance science

Improving the Quality of Lab Reports by Using Them as Lab Instructions

ERIC Educational Resources Information Center

Haagen-Schuetzenhoefer, Claudia

2012-01-01

Lab exercises are quite popular in teaching science. Teachers have numerous goals in mind when teaching science laboratories. Nevertheless, empirical research draws a heterogeneous picture of the benefits of lab work. Research has shown that it does not necessarily contribute to the enhancement of practical abilities or content knowledge. Lab…

Computational Labs Using VPython Complement Conventional Labs in Online and Regular Physics Classes

NASA Astrophysics Data System (ADS)

Bachlechner, Martina E.

2009-03-01

Fairmont State University has developed online physics classes for the high-school teaching certificate based on the text book Matter and Interaction by Chabay and Sherwood. This lead to using computational VPython labs also in the traditional class room setting to complement conventional labs. The computational modeling process has proven to provide an excellent basis for the subsequent conventional lab and allows for a concrete experience of the difference between behavior according to a model and realistic behavior. Observations in the regular class room setting feed back into the development of the online classes.

National Programs | FNLCR Staging

Cancer.gov

The Frederick National Lab (FNL) is a shared national resource that offers access to a suite of advanced biomedical technologies, provides selected science and technology services, and maintains vast repositories of research materials available to bi

Contracting with the Frederick National Lab | FNLCR Staging

Cancer.gov

Our Acquisitions Directorate supports the national laboratory with high quality products and services to achieve its national mission. In addition to engaging large subcontractors, we are also committed to working with small businesses, minority- and

Optum Labs: building a novel node in the learning health care system.

PubMed

Wallace, Paul J; Shah, Nilay D; Dennen, Taylor; Bleicher, Paul A; Bleicher, Paul D; Crown, William H

2014-07-01

Unprecedented change in the US health care system is being driven by the rapid uptake of health information technology and national investments in multi-institution research networks comprising academic centers, health care delivery systems, and other health system components. An example of this changing landscape is Optum Labs, a novel network "node" that is bringing together new partners, data, and analytic techniques to implement research findings in health care practice. Optum Labs was founded in early 2013 by Mayo Clinic and Optum, a commercial data, infrastructure services, and care organization that is part of UnitedHealth Group. Optum Labs now has eleven collaborators and a database of deidentified information on more than 150 million people that is compliant with the Health Insurance Portability and Accountability Act (HIPAA) of 1996. This article describes the early progress of Optum Labs. The combination of the diverse collaborator perspectives with rich data, including deep patient and provider information, is intended to reveal new insights about diseases, treatments, and patients' behavior to guide changes in practice. Practitioners' involvement in agenda setting and translation of findings into practical care innovations accelerates the implementation of research results. Furthermore, feedback loops from the clinic help Optum Labs expand on successes and give quick attention to challenges as they emerge. Project HOPE—The People-to-People Health Foundation, Inc.

Spaceport Processing System Development Lab

NASA Technical Reports Server (NTRS)

Dorsey, Michael

2013-01-01

The Spaceport Processing System Development Lab (SPSDL), developed and maintained by the Systems Hardware and Engineering Branch (NE-C4), is a development lab with its own private/restricted networks. A private/restricted network is a network with restricted or no communication with other networks. This allows users from different groups to work on their own projects in their own configured environment without interfering with others utilizing their resources in the lab. The different networks being used in the lab have no way to talk with each other due to the way they are configured, so how a user configures his software, operating system, or the equipment doesn't interfere or carry over on any of the other networks in the lab. The SPSDL is available for any project in KSC that is in need of a lab environment. My job in the SPSDL was to assist in maintaining the lab to make sure it's accessible for users. This includes, but is not limited to, making sure the computers in the lab are properly running and patched with updated hardware/software. In addition to this, I also was to assist users who had issues in utilizing the resources in the lab, which may include helping to configure a restricted network for their own environment. All of this was to ensure workers were able to use the SPSDL to work on their projects without difficulty which would in turn, benefit the work done throughout KSC. When I wasn't working in the SPSDL, I would instead help other coworkers with smaller tasks which included, but wasn't limited to, the proper disposal, moving of, or search for essential equipment. I also, during the free time I had, used NASA's resources to increase my knowledge and skills in a variety of subjects related to my major as a computer engineer, particularly in UNIX, Networking, and Embedded Systems.

SOUTH WING, MTR661. INTERIOR DETAIL INSIDE LAB ROOM 131. CAMERA ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

SOUTH WING, MTR-661. INTERIOR DETAIL INSIDE LAB ROOM 131. CAMERA FACING NORTHEAST. NOTE CONCRETE BLOCK WALLS. SAFETY SHOWER AND EYE WASHER AT REAR WALL. INL NEGATIVE NO. HD46-7-2. Mike Crane, Photographer, 2/2005. - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

LPT. Shield test facility (TAN645 and 646). Calibration lab shield ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

LPT. Shield test facility (TAN-645 and -646). Calibration lab shield door. Ralph M. Parsons 1229-17 ANP/GE-6-645-MS-1. April 1957. Approved by INEEL Classification Office for public release. INEEL index code no. 037-0645-40-693-107369 - Idaho National Engineering Laboratory, Test Area North, Scoville, Butte County, ID

My Green Car: The Adventure Begins (Ep. 1) – DOE Lab-Corps Video Series

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saxena, Samveg; Shah, Nihar; Hansen, Dana

One key difference between a great technology that stays in the lab and one that reaches the marketplace is customer interest. In Episode 1, the Lab’s MyGreenCar team gets ready to step outside the lab and test their technology’s value to consumers in a scientific way. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates formore » consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.« less

LabVIEW: a software system for data acquisition, data analysis, and instrument control.

PubMed

Kalkman, C J

1995-01-01

Computer-based data acquisition systems play an important role in clinical monitoring and in the development of new monitoring tools. LabVIEW (National Instruments, Austin, TX) is a data acquisition and programming environment that allows flexible acquisition and processing of analog and digital data. The main feature that distinguishes LabVIEW from other data acquisition programs is its highly modular graphical programming language, "G," and a large library of mathematical and statistical functions. The advantage of graphical programming is that the code is flexible, reusable, and self-documenting. Subroutines can be saved in a library and reused without modification in other programs. This dramatically reduces development time and enables researchers to develop or modify their own programs. LabVIEW uses a large amount of processing power and computer memory, thus requiring a powerful computer. A large-screen monitor is desirable when developing larger applications. LabVIEW is excellently suited for testing new monitoring paradigms, analysis algorithms, or user interfaces. The typical LabVIEW user is the researcher who wants to develop a new monitoring technique, a set of new (derived) variables by integrating signals from several existing patient monitors, closed-loop control of a physiological variable, or a physiological simulator.

Astronomy Festival on the National Mall

NASA Astrophysics Data System (ADS)

Lubowich, D.

2015-11-01

The annual Astronomy Festival on the National Mall (AFNM) takes place on 11 acres north of the Washington Monument in June (previous AFNM were April and July). AFNM, sponsored by Hofstra University, features optical and radio telescope viewing of the Sun, Moon, planets, stars, clusters, and nebulae; a live large-screen image, a cell phone imaging mount; exhibits; hands-on activities; videos; large outdoor banners and posters; citizen science activities; hand-outs; bookmarks, and teacher information materials. With no tall buildings almost the entire sky is visible and 10th mag. moons of Saturn and the Ring Nebula (9.75 mag.) were easily visible on clear nights. Representatives from some of the nation's foremost scientific and educational institutions presented exciting demonstrations and activities; and answered questions about careers in science, celestial objects, and the latest astronomical discoveries. Local amateur astronomers set up twenty telescopes on the Mall and long lines of 20-30 people waited to look through the telescopes. Visitors met astronaut Dr. John Grunsfeld (Associate Administrator, NASA) and astronomers Dr. Lisse, Dr. Livengood, Dr. Warren, and Dr. Paul Hertz (Director, Astrophysics Division, NASA). Important historical astronomers spoke to the attendees: Caroline Herschel (Lynn King); Tycho Brahe (Dean Howarth); and Johannes Kepler (Jeff Jones). Free telescopes, donated by Celestron, were raffled off.

Childhood Picture of Dr. von Braun

NASA Technical Reports Server (NTRS)

1912-01-01

This is a childhood picture of Dr. von Braun (center) with his brothers. Dr. Wernher von Braun was born in Wirsitz, Germany, March 23, 1912. His childhood dreams of marned space flight were fulfilled when giant Saturn rockets, developed under his direction at NASA's Marshall Space Flight Center, boosted the manned Apollo spacecraft to the Moon. His life was dedicated to expanding man's knowledge through the exploration of space.

The Mission Planning Lab: A Visualization and Analysis Tool

NASA Technical Reports Server (NTRS)

Daugherty, Sarah C.; Cervantes, Benjamin W.

2009-01-01

Simulation and visualization are powerful decision making tools that are time-saving and cost-effective. Space missions pose testing and e valuation challenges that can be overcome through modeling, simulatio n, and visualization of mission parameters. The National Aeronautics and Space Administration?s (NASA) Wallops Flight Facility (WFF) capi talizes on the benefits of modeling, simulation, and visualization to ols through a project initiative called The Mission Planning Lab (MPL ).

The HLA-DRB9 gene and the origin of HLA-DR haplotypes.

PubMed

Gongora, R; Figueroa, F; Klein, J

1996-11-01

HLA-DRB9 is a gene fragment consisting of exon 2 and flanking intron sequences. It is located at the extreme end of the DRB subregion, whose other end is demarcated by the DRB1 locus. We sequenced approximately 1400 base pairs of the segment encompassing the DRB9 locus from eight human haplotypes (DR1, DR10, DR2, DR3, DR5, DR6, DR8, and DR9, the DR4 and DR7 having been sequenced by others earlier), as well as two chimpanzee, five gorillas, one orangutan and one macaque haplotype. The analysis of these sequences indicates that the DRB9 locus, which we estimate to be more than 58 million years (my) old, has been coevolving with the DRB1 locus for the last 4.2 my. As a consequence of this coevolution, the human DRB9 alleles fall into groups that correlate with the DRB1 allelic groups and with the gene organization of the human haplotypes. This observation implies that the present-day HLA-DR haplotype groups (DR1, DR51, DR52, DR8, and DR53) were founded more than 4 my ago and have remained intact (barring minor internal rearrangements that did not recombine the DRB1 and DRB9 genes) for this period of time. The haplotypes have been transmitted during speciations from ancestral to emerging species just like allelic lineages at the DRB1 locus. Thus not only allelic but also haplotype polymorphism evolves trans-specifically.

April Spotlight: National Minority Health Month

Cancer.gov

Each April, we recognize National Minority Health Month and National Minority Cancer Awareness Week. Dr. Peter Ogunbiyi shares how CRCHD’s work is related to the 2017 theme: Bridging Health Equity Across Communities.

Gaia DR2 documentation Chapter 7: Variability

NASA Astrophysics Data System (ADS)

Eyer, L.; Guy, L.; Distefano, E.; Clementini, G.; Mowlavi, N.; Rimoldini, L.; Roelens, M.; Audard, M.; Holl, B.; Lanzafame, A.; Lebzelter, T.; Lecoeur-Taïbi, I.; Molnár, L.; Ripepi, V.; Sarro, L.; Jevardat de Fombelle, G.; Nienartowicz, K.; De Ridder, J.; Juhász, Á.; Molinaro, R.; Plachy, E.; Regibo, S.

2018-04-01

This chapter of the Gaia DR2 documentation describes the models and methods used on the 22 months of data to produce the Gaia variable star results for Gaia DR2. The variability processing and analysis was based mostly on the calibrated G and integrated BP and RP photometry. The variability analysis approach to the Gaia data has been described in Eyer et al. (2017), and the Gaia DR2 results are presented in Holl et al. (2018). Detailed methods on specific topics will be published in a number of separate articles. Variability behaviour in the colour magnitude diagram is presented in Gaia Collaboration et al. (2018c).

Short Distance of Nuclei - Mining the Wealth of Existing Jefferson Lab Data - Final Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Weinstein, Lawrence; Kuhn, Sebastian

Over the last fifteen years of operation, the Jefferson Lab CLAS Collaboration has performed many experiments using nuclear targets. Because the CLAS detector has a very large acceptance and because it used a very open (i.e., nonspecific) trigger, there is a vast amount of data on many different reaction channels yet to be analyzed. The goal of the Jefferson Lab Nuclear Data Mining grant was to (1) collect the data from nuclear target experiments using the CLAS detector, (2) collect the associated cuts and corrections used to analyze that data, (3) provide non-expert users with a software environment for easymore » analysis of the data, and (4) to search for interesting reaction signatures in the data. We formed the Jefferson Lab Nuclear Data Mining collaboration under the auspices of this grant. The collaboration successfully carried out all of our goals. Dr. Gavalian, the data mining scientist, created a remarkably user-friendly web-based interface to enable easy analysis of the nuclear-target data by non-experts. Data from many of the CLAS nuclear target experiments has been made available on servers at Old Dominion University. Many of the associated cuts and corrections have been incorporated into the data mining software. The data mining collaboration was extraordinarily successful in finding interesting reaction signatures in the data. Our paper Momentum sharing in imbalanced Fermi systems was published in Science. Several analyses of CLAS data are continuing and will result in papers after the end of the grant period. We have held several analysis workshops and have given many invited talks at international conferences and workshops related to the data mining initiative. Our initiative to maximize the impact of data collected with CLAS in the 6-GeV era was very successful. During the hiatus between the end of 6-GeV experiments and the beginning of 12-GeV experiments, our collaboration and the physics community at large benefited tremendously from the

VizieR Online Data Catalog: KODIAQ DR2 (O'Meara+, 2017)

NASA Astrophysics Data System (ADS)

O'Meara, J. M.; Lehner, N.; Howk, J. C.; Prochaska, J. X.; Fox, A. J.; Peeples, M. S.; Tumlinson, J.; O'Shea, B. W.

2018-02-01

The new data presented here in DR2 all stem from High-Resolution Echelle Spectrograph (HIRES) observations by multiple PIs between 1995 and 2004. Table1 presents the HIRES deckers used across DR2 and their corresponding spectral resolution. As with DR1, the majority of observations were made with the C1 or C5 decker providing ~6 and ~8km/s FWHM resolution, respectively. The Keck Observatory Database of Ionized Absorption toward Quasars (KODIAQ) DR2 comprises HIRES observations of 300 quasar lines of sight in total. Of these, 130 quasar sight lines are new since DR1 (O'Meara et al. 2015, Cat. J/AJ/150/111), along with many new additional observations of some of the DR1 quasars. Table2 presents the new data since DR1. Table3 presents the full DR2 sample of 300 quasars. (3 data files).

Teaching medicine with the help of "Dr. House".

PubMed

Jerrentrup, Andreas; Mueller, Tobias; Glowalla, Ulrich; Herder, Meike; Henrichs, Nadine; Neubauer, Andreas; Schaefer, Juergen R

2018-01-01

TV series such as "House MD", "Grey´s Anatomy" or "Emergency Room" are well perceived by medical students. Seminars featuring medical TV series such as "House MD" might serve as door-opener to attract medical students to learn more about rare diseases. The TV series "House MD" is troublesome for the main character Dr. House is an excellent diagnostician but at the same time a rather misanthropic person. Therefore, lecturing medicine with the help of "House MD" requires constant evaluation. From 2008 to 2016 we are using the well-known TV series "House MD" continuously to attract medical students and teach them about rare diseases as well as diagnostic strategies. We collected from 213 students a detailed questionnaire assessing their learning experience. 76.6% of our students (n = 157) reported to watching medical dramas on a regular basis. The Dr. House seminar was compared to traditional seminars and our students reported an improved learning effect (69.9%), better concentration (89.7%), higher motivation to participate (88.7%), and more fun (86.7%) (all p<0.001). The students see Dr. House's behavior quite critically. Likert assessment on a 5-point scale identified strong disagreement with Dr. House´s interpersonal skills in dealing with his colleagues (median = 1) and patients (median = 1). At the same time, the students strongly agreed with his outstanding diagnostic (median = 5) and therapeutic capabilities (median = 4). Medical students visiting a Dr. House teaching seminar are highly motivated to learn more about rare diseases. They were positively influenced by TV series such as Dr. House to improve their diagnostic and clinical skills. At the same time, they are critical enough not to see Dr. House as a role model for their own personality. Well performed medical TV shows such as Dr. House can successfully be used in an educational setting to motivate medical students to come into seminars to learn more about rare diseases.

Ernest Orlando Lawrence Awards Ceremony for 2011 Award Winners (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

ScienceCinema

Chu, Steven [U.S. Energy Secretary

2018-01-12

The winners for 2011 of the Department of Energy's Ernest Orlando Lawrence Award were recognized in a ceremony held May 21, 2012. Dr. Steven Chu and others spoke of the importance of the accomplishments and the prestigious history of the award. The recipients of the Ernest Orlando Lawrence Award for 2011 are: Riccardo Betti (University of Rochester); Paul C. Canfield (Ames Laboratory); Mark B. Chadwick (Los Alamos National Laboratory); David E. Chavez (Los Alamos National Laboratory); Amit Goyal (Oak Ridge National Laboratory); Thomas P. Guilderson (Lawrence Livermore National Laboratory); Lois Curfman McInnes (Argonne National Laboratory); Bernard Matthew Poelker (Thomas Jefferson National Accelerator Facility); and Barry F. Smith (Argonne National Laboratory).

Defense.gov Special Report: Dr. Jill Biden

Science.gov Websites

. "I feel like you are my extended family." Story More Stories Dr. Biden Welcomes Guard Children Support Bidens Welcome Soldiers Home at Fort Drum Military Children Deserve America's Support Dr. Biden Guard Children Bidens Visit Iraq for Fourth Festivities More Photo Essays Bidens Welcome Troops Home at

Dr. von Braun Tries Out the NBS

NASA Technical Reports Server (NTRS)

1967-01-01

Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown fitted with suit and diving equipment as he prepares for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

The National "Expertise Gap"

ERIC Educational Resources Information Center

Hamilton, Kendra

2005-01-01

This article discusses the Woodrow Wilson National Fellowship Foundation's report, "Diversity and the Ph.D.," released in May, which documents in troubling detail the exact dimensions of what the foundation's president, Dr. Robert Weisbuch, is calling the national "expertise gap." Weisbuch states that the expertise gap extends beyond the…

Building National Capacity To Implement National Forest Monitoring System In Africa By GLAD

NASA Astrophysics Data System (ADS)

Lola Amani, P. K.

2017-12-01

Earth Observation data provide numerous information on the earth and its phenomena from space/satellite. They also offer the ability to compile and analyze information at global or local scales in a timely manner. However, to use them, it is important to develop methods that can enable the extraction of the desired information. Such methods should be robust and consistent enough to be considered for national monitoring systems. At the University of Maryland, the Global Land Analysis and Discovery (GLAD) Laboratory, led by Dr. Hansen, has developed automatic methods using Landsat data that have been applied for the Global Forest Change (GFC) in collaboration with the World Resources Institute (WRI), Google and others to providing information on tree cover loss throughout the global on a yearly basis, and on a daily basis a tree cover loss alert system to improve transparency and accessible at GFW Initiative (Global Forest Watch) website. Following the increasing interest in utilizing the GFC data, the GLAD Laboratory is working closely with national governments of different countries to reinforce their capacities in using the data in the best way and implementing the methodological framework for supporting their national forest monitoring, notification, and reporting (MNV) system. More precisely, the Lab supports step by step the countries in developing their reference emission levels and/or forest reference levels based on the country-specific needs, goals, and requirements, including the definition of the forest. Once in place, the methodology can easily be extended to different applications, such as monitoring the droughts events, etc. Here, we present the work accomplished with the national agencies of some countries in Africa, like Cameroon, Republic of Congo and Madagascar with the support of the Silva-Carbon and USAID-CARPE Programs and WRI. These countries are mainly engaged at different levels of the REDD+ process. Keywords: Earth Observation, Landsat data

[The Nobel Prize for nitric oxide. The unjust exclusion of Dr. Salvador Moncada].

PubMed

de Berrazueta, J R

1999-04-01

The 1998 Nobel Prize in Physiology and Medicine has been awarded jointly to North-American scientists, Dr Robert F. Furchgott, Louis J. Ignarro and Ferid Murad, for their discoveries in relation to "nitric oxide as a signalling molecule in the cardiovascular system". This has raised an important polemic because of the exclusion the South-American scientist, now nationalized British, Dr. Salvador Moncada. This short historical review examines some of the fundamental contributions to the knowledge in this field. It shows the sequence of the discoveries and the communication of them to the scientific community by the rewarded scientists and by Dr. Moncada. It is based on some fundamental publications in order to better understand this story, which does not coincide with the writing in 1996 by the Lasker Prize Committee, and which in 1998 was re-written again by the Nobel Committee of the Swedish Academy. More than 90 universities, academies and societies have acknowledged Dr. Moncada up to now with priority in the discovery of the fact that nitric oxide is released by endothelial cells, and the revealing of its metabolic way. More than 20,000 citations of their fundamental papers endorse in the scientific community his primacy in this field. Even Robert Furchgott, author of the brilliant discovery of the endothelium derived relaxing factor, that opened this field to the science, declared about the award of the 1998 Nobel Prize: "I feel that the Nobel Prize Committee could have made an exception this year and chosen a fourth person, Salvador Moncada (to share the prize)".

GeneLab: Open Science For Exploration

NASA Technical Reports Server (NTRS)

Galazka, Jonathan

2018-01-01

The NASA GeneLab project capitalizes on multi-omic technologies to maximize the return on spaceflight experiments. The GeneLab project houses spaceflight and spaceflight-relevant multi-omics data in a publicly accessible data commons, and collaborates with NASA-funded principal investigators to maximize the omics data from spaceflight and spaceflight-relevant experiments. I will discuss the current status of GeneLab and give specific examples of how the GeneLab data system has been used to gain insight into how biology responds to spaceflight conditions.

Dr. Albert Carr--Science Educator 1930-2000

ERIC Educational Resources Information Center

Lopez, Leslie

2013-01-01

The very first issue of "Educational Perspectives" was published in October of 1962. Dr. Albert Carr wrote one of the inaugural essays on the topic of current developments in science education, and he went on to write several other articles for the journal. This article shares why Dr. Albert Carr's colleagues remember him for his…

A Museum Learning Lab

ERIC Educational Resources Information Center

Vandiver, Kathleen M.; Bijur, Jon Markowitz; Epstein, Ari W.; Rosenthal, Beryl; Stidsen, Don

2008-01-01

The "Learning Lab: The Cell" exhibit was developed by the Massachusetts Institute of Technology (MIT) Museum and the MIT Center for Environmental Health Sciences (CEHS). Specially designed for middle and high school students, the Learning Lab provides museum visitors of all ages with fascinating insights into how our living cells work. The…

Designing a ruggedisation lab to characterise materials for harsh environments.

PubMed

Frazzette, Nicholas; Jethva, Janak; Mehta, Khanjan; Stapleton, Joshua J; Randall, Clive

Designing products for use in developing countries presents a unique set of challenges including harsh operating environments, costly repairs and maintenance, and users with varying degrees of education and device familiarity. For products to be robust, adaptable and durable, they need to be ruggedised for environmental factors such as high temperature and humidity as well as different operational conditions such as shock and chemical exposure. The product characterisation and ruggedisation processes require specific expertise and resources that are seldom available outside of large corporations and elite national research labs. There is no standardised process since product needs strongly depend on the context and user base, making it particularly onerous for underfunded start-ups and academic groups. Standardised protocols that identify essential lab testing regimens for specific contexts and user groups can complement field-testing and accelerate the product development process while reducing costs. This article synthesises current methods and strategies for product testing employed by large corporations as well as defence-related entities. A technological and organisational framework for a service-for-fee product characterisation and ruggedisation lab that reduces costs and shortens the timespan from product invention to commercial launch in harsh settings is presented.

Evaluation of Inter-Mountain Labs infrasound sensors : July 2007.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hart, Darren M.

2007-10-01

Sandia National Laboratories has tested and evaluated three Inter Mountain Labs infrasound sensors. The test results included in this report were in response to static and tonal-dynamic input signals. Most test methodologies used were based on IEEE Standards 1057 for Digitizing Waveform Recorders and 1241 for Analog to Digital Converters; others were designed by Sandia specifically for infrasound application evaluation and for supplementary criteria not addressed in the IEEE standards. The objective of this work was to evaluate the overall technical performance of the Inter Mountain Labs (IML) infrasound sensor model SS. The results of this evaluation were only comparedmore » to relevant noise models; due to a lack of manufactures documentation notes on the sensors under test prior to testing. The tests selected for this system were chosen to demonstrate different performance aspects of the components under test.« less

My Green Car: The Adventure Begins (Ep. 1) – DOE Lab-Corps Video Series

ScienceCinema

Saxena, Samveg; Shah, Nihar; Hansen, Dana

2018-06-12

One key difference between a great technology that stays in the lab and one that reaches the marketplace is customer interest. In Episode 1, the Lab’s MyGreenCar team gets ready to step outside the lab and test their technology’s value to consumers in a scientific way. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates for consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.

Dr. Zakir Husain on Education and Language

ERIC Educational Resources Information Center

Kumar, Deepak; Radha Gayathri, Ch.

2017-01-01

Dr. Zakir Husain is known as a self-less nationalist leader and also as an educationist "par excellence." Taking a cue from his educational ideas like the "Nai Talim," this article brings into focus his views on the medium-conundrum. Dr. Husain was very clear about the role of Indian languages and the relevance of mother…

Lab-on a-Chip

NASA Technical Reports Server (NTRS)

2003-01-01

Helen Cole, the project manager for the Lab-on-a-Chip Applications Development program, and Lisa Monaco, the project scientist for the program, insert a lab on a chip into the Caliper 42 which is specialized equipment that controls processes on commercial chips to support development of lab-on-a-chip applications. The system has special microscopes and imaging systems, so scientists can process and study different types of fluid, chemical, and medical tests conducted on chips. For example, researchers have examined fluorescent bacteria as it flows through the chips' fluid channels or microfluidic capillaries. Researchers at NASA's Marshall Space Flight Center (MSFC) in Huntsville, Alabama, have been studying how the lab-on-a-chip technology can be used for microbial detection, water quality monitoring, and detecting biosignatures of past or present life on Mars. The Marshall Center team is also collaborating with scientists at other NASA centers and at universities to develop custom chip designs for not only space applications, but for many Earth applications, such as for detecting deadly microbes in heating and air systems. (NASA/MSFC/D.Stoffer)

ERLN Lab Compendium Fact Sheet

EPA Pesticide Factsheets

The Compendium is an online database of environmental testing laboratories nationwide. It enables labs to create profiles of their capabilities, so emergency responders can quickly identify a lab that will meet their support needs.

Physics Labs with Flavor

ERIC Educational Resources Information Center

Agrest, Mikhail M.

2009-01-01

This paper describes my attempts to look deeper into the so-called "shoot for your grade" labs, started in the '90s, when I began applying my teaching experience in Russia to introductory physics labs at the College of Charleston and other higher education institutions in South Carolina. The term "shoot for your grade" became popular among…

Making Real Virtual Labs

ERIC Educational Resources Information Center

Keller, Harry E.; Keller, Edward E.

2005-01-01

Francis Bacon began defining scientific methodology in the early 17th century, and secondary school science classes began to implement science labs in the mid-19th century. By the early 20th century, leading educators were suggesting that science labs be used to develop scientific thinking habits in young students, and at the beginning of the 21st…

NOT Another Lab Report

ERIC Educational Resources Information Center

Ende, Fred

2012-01-01

Ask students to name the aspects of science class they enjoy most, and working on labs will undoubtedly be mentioned. What often won't be included, however, is writing lab reports. For many students, the process of exploration and data collection is paramount, while the explanation and analysis of findings often takes a backseat. After all, if…

Are Virtual Labs as Effective as Hands-on Labs for Undergraduate Physics? A Comparative Study at Two Major Universities

ERIC Educational Resources Information Center

Darrah, Marjorie; Humbert, Roxann; Finstein, Jeanne; Simon, Marllin; Hopkins, John

2014-01-01

Most physics professors would agree that the lab experiences students have in introductory physics are central to the learning of the concepts in the course. It is also true that these physics labs require time and money for upkeep, not to mention the hours spent setting up and taking down labs. Virtual physics lab experiences can provide an…

The Development of MSFC Usability Lab

NASA Technical Reports Server (NTRS)

Cheng, Yiwei; Richardson, Sally

2010-01-01

This conference poster reviews the development of the usability lab at Marshall Space Flight Center. The purpose of the lab was to integrate a fully functioning usability laboratory to provide a resource for future human factor assessments. and to implement preliminary usability testing on a MSFC website to validate the functionality of the lab.

Dr. Robert Goddard

NASA Image and Video Library

2017-12-08

Dr. Robert Goddard's rocket ready for flight. Roswell, New Mexico. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Ask Dr. Sue.

ERIC Educational Resources Information Center

Aronson, Susan S.

1990-01-01

Discusses the need for child care providers to be sure children in their care who are between the ages of 15 months and 5 years have had Haemophilus influenzae type b (Hib) vaccine. Urges child care center staff to avoid use of bean bag infant cushions and to inform parents about the hazards posed by the cushions. (DR)

76 FR 11526 - In the Matter of Dr. Gary Kao; Order Prohibiting Involvement In NRC-Licensed Activities

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-02

... patients until December 2007. In response to the reported medical events, the VA National Health Physics... health or to minimize the danger to life or property in compliance with the Commission's requirements. Therefore, the public health, safety and interest require that Dr. Kao be prohibited from any involvement in...

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials Investigators Division Staff Facilities and Centers Staff Jobs Safety Personnel Resources Committees In Case of

Dr. Shawn Mehlenbacher 2012 Wilder Silver Medal Recipient

USDA-ARS?s Scientific Manuscript database

Dr. Shawn Mehlenbacher, Oregon State University, was awarded the 2012 Wilder Medal by the American Pomological Society for his contributions to hazelnut genetics and cultivar development. Dr. Mehlenbacher took over the leadership of the Oregon State University hazelnut breeding program in 1986 aft...

Labs That Are a Blast.

ERIC Educational Resources Information Center

Hendrix, Laura

1996-01-01

Presents activities that use a simple homemade apparatus called "the cannon" to demonstrate Newton's Third Law. Reviews the chemistry concepts behind the ignition of the cannon and presents the Momentum Lab and the Projectile Motion Lab. (JRH)

Ernest Orlando Lawrence Awards Ceremony for 2011 Award Winners (Presentations, including remarks by Energy Secretary, Dr. Steven Chu)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chu, Steven

The winners for 2011 of the Department of Energy's Ernest Orlando Lawrence Award were recognized in a ceremony held May 21, 2012. Dr. Steven Chu and others spoke of the importance of the accomplishments and the prestigious history of the award. The recipients of the Ernest Orlando Lawrence Award for 2011 are: Riccardo Betti (University of Rochester); Paul C. Canfield (Ames Laboratory); Mark B. Chadwick (Los Alamos National Laboratory); David E. Chavez (Los Alamos National Laboratory); Amit Goyal (Oak Ridge National Laboratory); Thomas P. Guilderson (Lawrence Livermore National Laboratory); Lois Curfman McInnes (Argonne National Laboratory); Bernard Matthew Poelker (Thomas Jeffersonmore » National Accelerator Facility); and Barry F. Smith (Argonne National Laboratory).« less

Beyond Classroom, Lab, Studio and Field

NASA Astrophysics Data System (ADS)

Waller, J. L.; Brey, J. A.; DeMuynck, E.; Weglarz, T. C.

2017-12-01

When the arts work in tandem with the sciences, the insights of these disciplines can be easily shared and teaching and learning are enriched. Our shared experiences in classroom/lab/studio instruction and in art and science based exhibitions reward all involved. Our individual disciplines cover a wide range of content- Art, Biology, Geography, Geology- yet we connect on aspects that link to the others'. We easily move from lab to studio and back again as we teach—as do our students as they learn! Art and science education can take place outside labs and studios through study abroad, international workshops, museum or gallery spaces, and in forums like the National Academies' programs. We can reach our neighbors at local public gatherings, nature centers and libraries. Our reach is extended in printed publications and in conferences. We will describe some of our activities listed above, with special focus on exhibitions: "Layers: Places in Peril"; "small problems, BIG TROUBLE" and the in-progress "River Bookends: Headwaters, Delta and the Volume of Stories In Between". Through these, learning and edification take place between the show and gallery visitors and is extended via class visits and related assignments, field trips for child and adult learners, interviews, films and panel presentations. These exhibitions offer the important opportunities for exhibit- participating scientists to find common ground with each other about their varied work. We will highlight a recent collaborative show opening a new university-based environmental research center and the rewarding activities there with art and science students and professors. We will talk about the learning enhancement added through a project that brought together a physical geography and a painting class. We will explore how students shared the form and content of their research projects with each other and then, became the educators through paintings and text of their geoscience topics on gallery walls.

RoboLab and virtual environments

NASA Technical Reports Server (NTRS)

Giarratano, Joseph C.

1994-01-01

A useful adjunct to the manned space station would be a self-contained free-flying laboratory (RoboLab). This laboratory would have a robot operated under telepresence from the space station or ground. Long duration experiments aboard RoboLab could be performed by astronauts or scientists using telepresence to operate equipment and perform experiments. Operating the lab by telepresence would eliminate the need for life support such as food, water and air. The robot would be capable of motion in three dimensions, have binocular vision TV cameras, and two arms with manipulators to simulate hands. The robot would move along a two-dimensional grid and have a rotating, telescoping periscope section for extension in the third dimension. The remote operator would wear a virtual reality type headset to allow the superposition of computer displays over the real-time video of the lab. The operators would wear exoskeleton type arms to facilitate the movement of objects and equipment operation. The combination of video displays, motion, and the exoskeleton arms would provide a high degree of telepresence, especially for novice users such as scientists doing short-term experiments. The RoboLab could be resupplied and samples removed on other space shuttle flights. A self-contained RoboLab module would be designed to fit within the cargo bay of the space shuttle. Different modules could be designed for specific applications, i.e., crystal-growing, medicine, life sciences, chemistry, etc. This paper describes a RoboLab simulation using virtual reality (VR). VR provides an ideal simulation of telepresence before the actual robot and laboratory modules are constructed. The easy simulation of different telepresence designs will produce a highly optimum design before construction rather than the more expensive and time consuming hardware changes afterwards.

Virtual Labs and Virtual Worlds

NASA Astrophysics Data System (ADS)

Boehler, Ted

2006-12-01

Virtual Labs and Virtual Worlds Coastline Community College has under development several virtual lab simulations and activities that range from biology, to language labs, to virtual discussion environments. Imagine a virtual world that students enter online, by logging onto their computer from home or anywhere they have web access. Upon entering this world they select a personalized identity represented by a digitized character (avatar) that can freely move about, interact with the environment, and communicate with other characters. In these virtual worlds, buildings, gathering places, conference rooms, labs, science rooms, and a variety of other “real world” elements are evident. When characters move about and encounter other people (players) they may freely communicate. They can examine things, manipulate objects, read signs, watch video clips, hear sounds, and jump to other locations. Goals of critical thinking, social interaction, peer collaboration, group support, and enhanced learning can be achieved in surprising new ways with this innovative approach to peer-to-peer communication in a virtual discussion world. In this presentation, short demos will be given of several online learning environments including a virtual biology lab, a marine science module, a Spanish lab, and a virtual discussion world. Coastline College has been a leader in the development of distance learning and media-based education for nearly 30 years and currently offers courses through PDA, Internet, DVD, CD-ROM, TV, and Videoconferencing technologies. Its distance learning program serves over 20,000 students every year. sponsor Jerry Meisner

The ORAC-DR data reduction pipeline

NASA Astrophysics Data System (ADS)

Cavanagh, B.; Jenness, T.; Economou, F.; Currie, M. J.

2008-03-01

The ORAC-DR data reduction pipeline has been used by the Joint Astronomy Centre since 1998. Originally developed for an infrared spectrometer and a submillimetre bolometer array, it has since expanded to support twenty instruments from nine different telescopes. By using shared code and a common infrastructure, rapid development of an automated data reduction pipeline for nearly any astronomical data is possible. This paper discusses the infrastructure available to developers and estimates the development timescales expected to reduce data for new instruments using ORAC-DR.

Improving the Testing Environment of a Lab Transition-Edge Sensor: An Exercise in Nulling Earth’s Magnetic Field

NASA Astrophysics Data System (ADS)

Melton, Casey; McCammon Lab at University of Wisconsin-Madison

2018-01-01

In Dr. Dan McCammon’s lab at the University of Wisconsin-Madison, a special class of x-ray microcalorimeter called a Transition-Edge Sensor, or TES, is being tested in order to identify the strengths and weaknesses of this device in detecting x-ray photons from astronomical sources. The TES is currently housed in a cryogenic refrigerator where it can be tested at superconducting temperatures. Although this refrigerator is equipped with magnetic field shielding to keep magnetic fields out during testing, latent magnetic fields are trapped inside the receptacle at the time of cool-down. To remedy this problem, I built a set of tri-axial Helmholtz coils, which have at their center a uniform volume of magnetic field. This uniform region can be tuned prior to cool-down and nulls the magnetic field that would typically be trapped inside the receptacle. The magnetic field will be monitored inside the receptacle with a tri-axial fluxgate magnetic field sensor, which I began designing in the latter half of the project. This project is still in progress, and will be implemented in the lab in the near future.

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Goddard's rocket nose cone, parachute, and relase device, April 19, 1935. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Goddard with batteries and relay at the launch tower, May 19, 1937. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Dr. von Braun With German Rocket Experimenters

NASA Technical Reports Server (NTRS)

1930-01-01

Dr. von Braun was among a famous group of rocket experimenters in Germany in the 1930s. This photograph is believed to be made on the occasion of Herman Oberth's Kegelduese liquid rocket engine being certified as to performance during firing. From left to right are R. Nebel, Dr. Ritter, Mr. Baermueller, Kurt Heinish, Herman Oberth, Klaus Riedel, Wernher von Braun, and an unidentified person.

GeneLab

NASA Technical Reports Server (NTRS)

Berrios, Daniel C.; Thompson, Terri G.

2015-01-01

NASA GeneLab is expected to capture and distribute omics data and experimental and process conditions most relevant to research community in their statistical and theoretical analysis of NASAs omics data.

Gaia DR2 documentation Chapter 8: Astrophysical Parameters

NASA Astrophysics Data System (ADS)

Manteiga, M.; Andrae, R.; Fouesneau, M.; Creevey, O.; Ordenovic, C.; Mary, N.; Jean-Antoine-Piccolo, A.; Bailer-Jones, C. A. L.

2018-04-01

This chapter of the Gaia DR2 documentation describes Apsis, the Astrophysical Parameters Inference System used for processing Gaia DR2 data. Beyond this documentation, a complete description of the processing and the results, as well as additional validations, have been published in Andrae et al. (2018).

Interview with Sanofi's Dr Tunde Falode.

PubMed

Falode, Tunde

2017-01-01

Dr Tunde Falode speaks to Elena Conroy, Commissioning Editor: Dr Tunde Falode is General Manager for the Diabetes and Cardiovascular Business Unit in the UK and Ireland at Sanofi, a global pharmaceutical company. Following graduation from the University of Jos Medical School in Nigeria, he secured a basic surgical training post through Guy's and St Thomas' hospitals in London, eventually specializing in cardiac and thoracic surgery, before changing his career path. In addition to his current role at Sanofi, he recently completed his specialist training in pharmaceutical medicine and has a keen interest in sports.

ORAC-DR: Overview and General Introduction

NASA Astrophysics Data System (ADS)

Economou, Frossie; Jenness, Tim; Currie, Malcolm J.; Adamson, Andy; Allan, Alasdair; Cavanagh, Brad

ORAC-DR is a general purpose automatic data reduction pipeline environment. It currently supports data reduction for the United Kingdom Infrared Telescope (UKIRT) instruments UFTI, IRCAM, UIST and CGS4, for the James Clerk Maxwell Telescope (JCMT) instrument SCUBA, for the William Herschel Telescope (WHT) instrument INGRID, for the European Southern Observatory (ESO) instrument ISAAC and for the Anglo-Australian Telescope (AAT) instrument IRIS-2. This document describes the general pipeline environment. For specific information on how to reduce the data for a particular instrument, please consult the appropriate ORAC-DR instrument guide.

Dr. Tulp's Anatomy Lesson by Rembrandt: the third day hypothesis.

PubMed

Afek, Arnon; Friedman, Tal; Kugel, Chen; Barshack, Iris; Lurie, Doron J

2009-07-01

An autopsy was an important event in 17th century Holland. Autopsies were held in an 'anatomy theater' and performed according to a fixed protocol that often took up to 3 days to complete. Of the five group portraits painted by Rembrandt over the course of his career, two were anatomy lessons given by Dr. Tulp and Dr. Deyman. An examination of Rembrandt's painting Dr. Tulp's Anatomy Lesson (1632) and an X-ray image of the painting, as compared to other paintings of anatomy lessons from the same period, reveal interesting differences, such as positioning, and light and shadow. Not only was the autopsy not performed according to the usual protocol, but in this painting Rembrandt created a unique dramatic scene in his effort to tell a story. We suggest that Dr. Tulp and Rembrandt "modified" the painting of Dr. Tulp's anatomy lesson to emphasize Dr. Tulp's position as the greatest anatomist of his era--"Vesalius of Amsterdam," and as a way of demonstrating God's greatness by highlighting the hand as a symbol of the most glorious of God's creations.

A virtual computer lab for distance biomedical technology education.

PubMed

Locatis, Craig; Vega, Anibal; Bhagwat, Medha; Liu, Wei-Li; Conde, Jose

2008-03-13

The National Library of Medicine's National Center for Biotechnology Information offers mini-courses which entail applying concepts in biochemistry and genetics to search genomics databases and other information sources. They are highly interactive and involve use of 3D molecular visualization software that can be computationally taxing. Methods were devised to offer the courses at a distance so as to provide as much functionality of a computer lab as possible, the venue where they are normally taught. The methods, which can be employed with varied videoconferencing technology and desktop sharing software, were used to deliver mini-courses at a distance in pilot applications where students could see demonstrations by the instructor and the instructor could observe and interact with students working at their remote desktops. Student ratings of the learning experience and comments to open ended questions were similar to those when the courses are offered face to face. The real time interaction and the instructor's ability to access student desktops from a distance in order to provide individual assistance and feedback were considered invaluable. The technologies and methods mimic much of the functionality of computer labs and may be usefully applied in any context where content changes frequently, training needs to be offered on complex computer applications at a distance in real time, and where it is necessary for the instructor to monitor students as they work.

Awakening interest in the natural sciences - BASF's Kids' Labs.

PubMed

Lang, Cinthia

2012-01-01

At BASF's Ludwigshafen headquarters, kids and young adults in grades 1-13 can learn about chemistry in the Kids' Labs. Different programs exist for different levels of knowledge. In the two 'Hands-on Lab H(2)O & Co.' Kids' Labs, students from grades 1-6 explore the secrets of chemistry. BASF Kids' Labs have now been set up in over 30 countries. In Switzerland alone, almost 2,000 students have taken part in the 'Water Loves Chemistry' Kids' Lab since it was started in 2011. In Alsace, 600 students have participated to date. In the Teens' Lab 'Xplore Middle School', middle school students explore five different programs with the themes 'substance labyrinth', 'nutrition', 'coffee, caffeine & co.', 'cosmetics' and 'energy'. Biotechnological methods are the focus of the Teens' Lab 'Xplore Biotech' for students taking basic and advanced biology courses. In the 'Xplore High School' Teens' Lab, chemistry teachers present their own experimental lab instruction for students in basic and advanced chemistry courses. The Virtual Lab has been expanding the offerings of the BASF Kids' Labs since 2011. The online lab was developed by the company for the International Year Of Chemistry and gives kids and young adults the opportunity to do interactive experiments outside of the lab.

An HPLC method associated with a thermodynamic analysis to compare the binding of TRAIL and its nanovectorized form to death receptors DR4 and DR5 and their relationship to cytotoxicity.

PubMed

Guillaume, Yves Claude; Lethier, Lydie; André, Claire

2016-11-15

TRAIL is a member of the TNF family of cytokines which induces apoptosis of cancer cells via its binding to its cognate receptors, DR5 a high affinity site and DR4 a site of low affinity. Our working group has recently demonstrated that nanovectorization of TRAIL with single wall carbon nanotubes (abbreviated NPT) enhanced TRAIL affinity to the high affinity site DR5 and increased pro apoptotic potential in different human tumor cell lines. In this paper, the DR4 low affinity site was immobilized on a chromatographic support and the effect of temperature on a wide temperature range 1°C-50°C was studied to calculate the thermodynamic parameters of the binding of TRAIL and NPT to DR4 and DR5 receptors. For the first time the heat capacity changes for the different binding processes were determined. At a physiological pH (7.4) the heat capacity changes for the binding of NPT to DR4 and DR5 were respectively equal to -0.91kJ/molK and -0.28kJ/molK and those obtained for the binding of TRAIL to DR4 and DR5 were respectively equal to -1.54kJ/molK and -1.05kJ/molK. By the use of differential scanning calorimetry (DSC), a phase transition (∼12°C for DR5, ∼4°C for DR4) between a disordered (low temperature) and an ordered (high temperature) solid like state visualized in the receptor structure confirmed the temperature dependence of binding affinity enthalpy ΔH for soluble TRAIL and its nanovectorized form to its cognate receptors. In the low temperature domain, the positive ΔH values contribute non-favourably to the free energy of binding, TRAIL and NPT described similar affinities for DR4 and DR5. For the high temperature domain, negative ΔH values indicated that van der Waals interactions and hydrogen bonding are engaged favourably at the ligand - receptor interface. Above 30°C, their rank-ordered affinities were thus strongly different in the sequence: TRAIL DR4 DR4 DR5 < NPT DR5 . The nanovectorization of TRAIL enhanced its binding to both DR4

Curricular Adaptations in Introductory Physics Labs

NASA Astrophysics Data System (ADS)

Dreyfus, Benjamin W.; Ewell, Mary; Moore, Kimberly

2017-01-01

When curricular materials are disseminated to new sites, there can be a tension between fidelity to the original intent of the developers and adaptation to local needs. In this case study we look at a lab activity that was initially developed for an introductory physics for the life sciences (IPLS) course at the University of Maryland, then implemented at George Mason University with significant adaptations. The goals of the two implementations were overlapping, but also differed in ways that are reflected in the two versions of the lab. We compare student lab report data from the two sites to examine the impacts of the adaptation on how students engaged with the lab.

Lab architecture

NASA Astrophysics Data System (ADS)

Crease, Robert P.

2008-04-01

There are few more dramatic illustrations of the vicissitudes of laboratory architecturethan the contrast between Building 20 at the Massachusetts Institute of Technology (MIT) and its replacement, the Ray and Maria Stata Center. Building 20 was built hurriedly in 1943 as temporary housing for MIT's famous Rad Lab, the site of wartime radar research, and it remained a productive laboratory space for over half a century. A decade ago it was demolished to make way for the Stata Center, an architecturally striking building designed by Frank Gehry to house MIT's computer science and artificial intelligence labs (above). But in 2004 - just two years after the Stata Center officially opened - the building was criticized for being unsuitable for research and became the subject of still ongoing lawsuits alleging design and construction failures.

ASC Tri-lab Co-design Level 2 Milestone Report 2015

DOE Office of Scientific and Technical Information (OSTI.GOV)

Hornung, Rich; Jones, Holger; Keasler, Jeff

2015-09-23

In 2015, the three Department of Energy (DOE) National Laboratories that make up the Advanced Sci- enti c Computing (ASC) Program (Sandia, Lawrence Livermore, and Los Alamos) collaboratively explored performance portability programming environments in the context of several ASC co-design proxy applica- tions as part of a tri-lab L2 milestone executed by the co-design teams at each laboratory. The programming environments that were studied included Kokkos (developed at Sandia), RAJA (LLNL), and Legion (Stan- ford University). The proxy apps studied included: miniAero, LULESH, CoMD, Kripke, and SNAP. These programming models and proxy-apps are described herein. Each lab focused on amore » particular combination of abstractions and proxy apps, with the goal of assessing performance portability using those. Performance portability was determined by: a) the ability to run a single application source code on multiple advanced architectures, b) comparing runtime performance between \

Bioengineering/Biophysicist Post-doctoral Fellow | Center for Cancer Research

Cancer.gov

A post-doctoral fellow position is available in the Tissue Morphodynamics Unit headed by Dr. Kandice Tanner at the National Cancer Institute. The Tanner lab combines biophysical and cell biological approaches to understand the interplay between tissue architecture and metastasis. We use a combination of imaging modalities, cell biology and animal models. It is expected that as a member of this lab, one will have an opportunity to be exposed to all these areas. We value a vibrant and collaborative environment where lab members share ideas, reagents and expertise and want to work on fundamental problems in the establishment of metastatic lesions. Our lab is located in the NIH main campus in Bethesda. The research facilities at NIH are outstanding and the lab has state-of-the-art equipment such as multi-photon and confocal microscopes, FACS facilities and animal vivarium.

Generalized Nanosatellite Avionics Testbed Lab

NASA Technical Reports Server (NTRS)

Frost, Chad R.; Sorgenfrei, Matthew C.; Nehrenz, Matt

2015-01-01

The Generalized Nanosatellite Avionics Testbed (G-NAT) lab at NASA Ames Research Center provides a flexible, easily accessible platform for developing hardware and software for advanced small spacecraft. A collaboration between the Mission Design Division and the Intelligent Systems Division, the objective of the lab is to provide testing data and general test protocols for advanced sensors, actuators, and processors for CubeSat-class spacecraft. By developing test schemes for advanced components outside of the standard mission lifecycle, the lab is able to help reduce the risk carried by advanced nanosatellite or CubeSat missions. Such missions are often allocated very little time for testing, and too often the test facilities must be custom-built for the needs of the mission at hand. The G-NAT lab helps to eliminate these problems by providing an existing suite of testbeds that combines easily accessible, commercial-offthe- shelf (COTS) processors with a collection of existing sensors and actuators.

Bioengineering/Biophysicist Postdoctoral Fellow | Center for Cancer Research

Cancer.gov

A post-doctoral fellow position is available in the Tissue Morphodynamics Unit headed by Dr. Kandice Tanner at the National Cancer Institute. The Tanner lab combines biophysical and cell biological approaches to understand the interplay between tissue architecture and metastasis. We use a combination of imaging modalities, cell biology and animal models. It is expected that as

Bioengineering/Biophysicist Post-doctoral Fellow | Center for Cancer Research

Cancer.gov

A post-doctoral fellow position is available in the Tissue Morphodynamics Unit headed by Dr. Kandice Tanner at the National Cancer Institute. The Tanner lab combines biophysical and cell biological approaches to understand the interplay between tissue architecture and metastasis. We use a combination of imaging modalities, cell biology and animal models. It is expected that as

Dr. von Braun with Seven Original Mercury Astronauts

NASA Technical Reports Server (NTRS)

1959-01-01

In this photo, Dr. Wernher von Braun, Director of the U.S. Army Ballistic Missile Agency's (ABMA) Development Operations Division, is shown briefing the seven original Mercury astronauts in ABMA's Fabrication Laboratory. (Left to right) Guss Grissom, Walter Schirra, Alan Shepard, John Glenn, Scott Carpenter, Gordon Cooper, Donald Slayton, and Dr. von Braun.

caNanoLab: data sharing to expedite the use of nanotechnology in biomedicine

PubMed Central

Gaheen, Sharon; Hinkal, George W.; Morris, Stephanie A.; Lijowski, Michal; Heiskanen, Mervi

2014-01-01

The use of nanotechnology in biomedicine involves the engineering of nanomaterials to act as therapeutic carriers, targeting agents and diagnostic imaging devices. The application of nanotechnology in cancer aims to transform early detection, targeted therapeutics and cancer prevention and control. To assist in expediting and validating the use of nanomaterials in biomedicine, the National Cancer Institute (NCI) Center for Biomedical Informatics and Information Technology, in collaboration with the NCI Alliance for Nanotechnology in Cancer (Alliance), has developed a data sharing portal called caNanoLab. caNanoLab provides access to experimental and literature curated data from the NCI Nanotechnology Characterization Laboratory, the Alliance and the greater cancer nanotechnology community. PMID:25364375

Plasma density characterization at SPARC_LAB through Stark broadening of Hydrogen spectral lines

NASA Astrophysics Data System (ADS)

Filippi, F.; Anania, M. P.; Bellaveglia, M.; Biagioni, A.; Chiadroni, E.; Cianchi, A.; Di Giovenale, D.; Di Pirro, G.; Ferrario, M.; Mostacci, A.; Palumbo, L.; Pompili, R.; Shpakov, V.; Vaccarezza, C.; Villa, F.; Zigler, A.

2016-09-01

Plasma-based acceleration techniques are of great interest for future, compact accelerators due to their high accelerating gradient. Both particle-driven and laser-driven Plasma Wakefield Acceleration experiments are foreseen at the SPARC_LAB Test Facility (INFN National Laboratories of Frascati, Italy), with the aim to accelerate high-brightness electron beams. In order to optimize the efficiency of the acceleration in the plasma and preserve the quality of the accelerated beam, the knowledge of the plasma electron density is mandatory. The Stark broadening of the Hydrogen spectral lines is one of the candidates used to characterize plasma density. The implementation of this diagnostic for plasma-based experiments at SPARC_LAB is presented.

Planning a Computer Lab: Considerations To Ensure Success.

ERIC Educational Resources Information Center

IALL Journal of Language Learning Technologies, 1994

1994-01-01

Presents points to consider when organizing a computer laboratory. These include the lab's overall objectives and how best to meet them; what type of students will use the lab; where the lab will be located; and what software and hardware can best meet the lab's overall objectives, population, and location requirements. Other factors include time,…

Overall properties of the Gaia DR1 reference frame

NASA Astrophysics Data System (ADS)

Liu, N.; Zhu, Z.; Liu, J.-C.; Ding, C.-Y.

2017-03-01

Aims: The first Gaia data release (Gaia DR1) provides 2191 ICRF2 sources with their positions in the auxiliary quasar solution and five astrometric parameters - positions, parallaxes, and proper motions - for stars in common between the Tycho-2 catalogue and Gaia in the joint Tycho-Gaia astrometric solution (TGAS). We aim to analyze the overall properties of Gaia DR1 reference frame. Methods: We compare quasar positions of the auxiliary quasar solution with ICRF2 sources using different samples and evaluate the influence on the Gaia DR1 reference frame owing to the Galactic aberration effect over the J2000.0-J2015.0 period. Then we estimate the global rotation between TGAS with Tycho-2 proper motion systems to investigate the property of the Gaia DR1 reference frame. Finally, the Galactic kinematics analysis using the K-M giant proper motions is performed to understand the property of Gaia DR1 reference frame. Results: The positional comparison between the auxiliary quasar solution and ICRF2 shows negligible orientation and validates the declination bias of -0.1mas in Gaia quasar positions with respect to ICRF2. Galactic aberration effect is thought to cause an offset 0.01mas of the Z axis direction of Gaia DR1 reference frame. The global rotation between TGAS and Tycho-2 proper motion systems, obtained by different samples, shows a much smaller value than the claimed value 0.24mas yr-1. For the Galactic kinematics analysis of the TGAS K-M giants, we find possible non-zero Galactic rotation components beyond the classical Oort constants: the rigid part ωYG = -0.38±0.15mas yr-1 and the differential part ω^primeYG = -0.29±0.19mas yr-1 around the YG axis of Galactic coordinates, which indicates possible residual rotation in Gaia DR1 reference frame or problems in the current Galactic kinematical model. Conclusions: The Gaia DR1 reference frame is well aligned to ICRF2, and the possible influence of the Galactic aberration effect should be taken into consideration

TQM in a Computer Lab.

ERIC Educational Resources Information Center

Swanson, Dewey A.; Phillips, Julie A.

At the Purdue University School of Technology (PST) at Columbus, Indiana, the Total Quality Management (TQM) philosophy was used in the computer laboratories to better meet student needs. A customer satisfaction survey was conducted to gather data on lab facilities, lab assistants, and hardware/software; other sections of the survey included…

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Synthesis Condensed Matter and Materials Physics Scattering and Instrumentation Science Centers Center for Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials Sciences Division About Organization Contact Research Core Programs Materials Discovery, Design and

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Dr. Robert Goddard's tower for "static" test near the shop at Roswell, New Mexico, 1930. The observation shelter (left foreground) is visible. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

Tail piece, with fixed movable air vanes, and vanes movable into the blast, of Dr. Robert Goddard's rocket, May 19, 1937. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Dr. Inside and Dr. Outside: Physicists Involved With National Security and Foreign Policy

NASA Astrophysics Data System (ADS)

Zimmerman, Peter D.

2009-05-01

Physicists have had a special interest in American national security and arms control since at least the Manhattan Project. They have served our country in uniform and in the career civil service. Some have left academic careers for brief periods to work as political appointees, consultants, or resident scholars and then returned to an academic life, but often with changed goals. Some have tried government life and left nearly immediately, while others dipped a toe in and decided to stay. I will look at real-life examples, mostly using real names, drawn from my career and circle of colleagues to try to explain why some physicists have been extremely successful, why others have not, and what happens to a physicist who moved to Washington and decides to stay. I will also discuss routes into public service for those interesting in giving it a try.

National Biocontainment Training Center

DTIC Science & Technology

2014-08-01

and Dr. Christopher Kasanga, Virologist, SACIDS, SUA. Pictured bottom right: Martha Betson, an instructor at Sokoine from the Royal Veterinary ...laboratories in the Pendik Veterinary Control Institute, which is a national research laboratory under the Turkish Ministry of Food, Agriculture and Livestock...Gargili (first row, center) for laboratory staff of the Pendik Veterinary Control Institute, a national research laboratory under the Turkish

Dr. Robert H. Goddard and His Rocket

NASA Technical Reports Server (NTRS)

2004-01-01

Goddard rocket with four rocket motors. This rocket attained an altitude of 200 feet in a flight, November 1936, at Roswell, New Mexico. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

Dr. Robert H. Goddard and His Rocket

NASA Technical Reports Server (NTRS)

1940-01-01

Goddard rocket in launching tower at Roswell, New Mexico, March 21, 1940. Fuel was injected by pumps from the fueling platform at left. From 1930 to 1941, Dr. Goddard made substantial progress in the development of progressively larger rockets, which attained altitudes of 2400 meters, and refined his equipment for guidance and control, his techniques of welding, and his insulation, pumps, and other associated equipment. In many respects, Dr. Goddard laid the essential foundations of practical rocket technology

Use of the D-R model to define trends in the emergence of Ceftazidime-resistant Escherichia coli in China

USDA-ARS?s Scientific Manuscript database

Objective: To assess the efficacy of the D-R model for defining trends in the appearance of Ceftazidime-resistant Escherichia coli. Methods: Actual data related to the manifestation of Ceftazidime-resistant E.coli spanning years 1996-2009 were collected from the China National Knowledge Internet (CN...

Design of inquiry-oriented science labs: impacts on students' attitudes

NASA Astrophysics Data System (ADS)

Baseya, J. M.; Francis, C. D.

2011-11-01

Background: Changes in lab style can lead to differences in learning. Two inquiry-oriented lab styles are guided inquiry (GI) and problem-based (PB). Students' attitudes towards lab are important to consider when choosing between GI and PB styles during curriculum design. Purpose: We examined the degree to which lab experiences are explained by a GI or a PB lab style vs. students' attitudes towards specific aspects of the experience, reflected by perceived excitement (exc), difficulty (dif), time efficiency (eff) and association between lab and lecture material (help). Sample: Approximately 1000 students attending first-semester, college biology lab for science majors at the University of Colorado at Boulder, USA, participated in the study. Design and method: In 2007, two labs were run as GI and one as PB. Formats were switched in 2008. Attitudes were assessed with a post-semester survey. Results: Only the four attitude variables (not lab style) had a strong relationship with overall lab rating which was most strongly related to exc, followed by dif and help/eff. Dif and eff had the greatest influence on attitudes for or against GI vs. PB labs, and help and exc had little influence on a GI vs. a PB lab. Also, when dif was low, students' attitudes were not significantly different between PB and GI labs, but when dif was high, students' significantly rated GI labs higher than PB labs. Conclusions: Students' attitudes towards lab are more dependent on specific aspects of the experience than on lab style. Changes in GI vs. PB lab styles primarily influence dif and eff rather than exc and help. Dif may be an important factor to consider when implementing a lab in the PB vs. the GI format. It might be good to go with a GI when dif is high and a PB when dif is low.

Science Lab: A Peer Approach.

ERIC Educational Resources Information Center

Ronca, Courtney C.

The two goals of this program were to increase the number of classroom teachers using the lab and to increase the amount of time that the science lab was used. The solution strategy chosen was a combination of peer tutoring, orientation presentations, small group discovery experiments and activities, and individual science experiment stations. The…

Innovation Incubator: Whisker Labs Technical Evaluation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sparn, Bethany F.; Frank, Stephen M.; Earle, Lieko

The Wells Fargo Innovation Incubator (IN2) is a program to foster and accelerate startup companies with commercial building energy-efficiency and demand management technologies. The program is funded by the Wells Fargo Foundation and co-administered by the National Renewable Energy Laboratory (NREL). Whisker Labs, an Oakland, California-based company, was one of four awardees in the first IN2 cohort and was invited to participate in the program because of its novel electrical power sensing technology for circuit breakers. The stick-on Whisker meters install directly on the front face of the circuit breakers in an electrical panel using adhesive, eliminating the need tomore » open the panel and install current transducers (CTs) on the circuit wiring.« less

Should pediatric patients wait for HLA-DR-matched renal transplants?

PubMed

Gritsch, H A; Veale, J L; Leichtman, A B; Guidinger, M K; Magee, J C; McDonald, R A; Harmon, W E; Delmonico, F L; Ettenger, R B; Cecka, J M

2008-10-01

Graft survival rates from deceased donors aged 35 years or less among all primary pediatric kidney transplant recipients in the United States between 1996 and 2004 were retrospectively examined to determine the effect of HLA-DR mismatches on graft survival. Zero HLA-DR-mismatched kidneys had statistically comparable 5-year graft survival (71%), to 1-DR-mismatched kidneys (69%) and 2-DR-mismatched kidneys (71%). When compared to donors less than 35 years of age, the relative rate of allograft failure was 1.32 (p = 0.0326) for donor age greater than or equal to age 35. There was no statistical increase in the odds of developing a panel-reactive antibody (PRA) greater than 30% at the time of second waitlisting, based upon the degree of HLA-A, -B or -DR mismatch of the first transplant, nor was there a 'dose effect' when more HLA antigens were mismatched between the donor and recipient. Therefore, pediatric transplant programs should utilize the recently implemented Organ Procurement and Transplantation Network's (OPTN)allocation policy, which prioritizes pediatric recipients to receive kidneys from deceased donors less than 35 years of age, and should not turn down such kidney offers to wait for a better HLA-DR-matched kidney.

Dr. David Sawyer, Mickey Mouse and Dr. David Brown attend a ceremony at Ronald McNair Middle School

NASA Technical Reports Server (NTRS)

1999-01-01

Dr. David Sawyer (left), Superintendent of the Brevard County School District, Mickey Mouse, and Dr. David Brown, a NASA astronaut, attend a tribute to NASA astronaut Ronald McNair held in the gymnasium of Ronald McNair Magnet School in Cocoa, Fla. During the tribute, Walt Disney World presented a portrait of McNair to the school, which had previously been renamed for the fallen astronaut. McNair was one of a crew of seven who lost their lives during an accident following launch of the Space Shuttle Challenger in January 1986.

Dr. Robert Goddard

NASA Image and Video Library

2017-12-08

1930--Dr. Robert Goddard built this 30 by 60 ft. workshop for rocket construction at the Mescalero Ranch, 3 miles northeast of Roswell, New Mexico. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Dr. Robert Goddard

NASA Image and Video Library

2017-12-08

The family home and birthplace of Dr. Robert Goddard in Worcester, Mass. was called Maple Hill and situated at Gates Lane, now called Tollawanda Drive. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Dr. Wernher Von Braun near the mobile launcher.

NASA Technical Reports Server (NTRS)

1999-01-01

Dr. George Mueller, NASA associate administrator for manned space flight, and Dr. Wernher Von Braun (right), director of the Marshall Space Flight Center, are seen near the mobile launcher carrying a 363 foot tall Saturn V space launch vehicle as the rocket is rolled from the vehicle assembly building at KSC for its three mile trip to the launch pad.

New Webpage Brings Increased Visibility to Frederick National Laboratory Subcontracting Opportunities | Frederick National Laboratory for Cancer Research

Cancer.gov

A new webpage will now make it easier for small businesses and others to find and apply for Frederick National Laboratory for Cancer Research business opportunities. The new solicitations page, which launched on the Frederick National Lab website Aug

LANGUAGE LABS--AN UPDATED REPORT.

ERIC Educational Resources Information Center

1963

REPORTS FROM SEVERAL SCHOOL DISTRICTS ON THE USE OF AND PLANNING OF LANGUAGE LABORATORIES ARE PRESENTED. LABORATORIES SHOULD BE ARRANGED FOR FLEXIBLE USE. THE AVERAGE HIGH SCHOOL STUDENT CAN USE A LAB PROFITABLY FOR 20 TO 25 MINUTES. THERE ARE THREE DIFFERENT TYPES OF LANGUAGE LABORATORIES THAT ARE DESCRIBED. THE SATELLITE LAB IS DIVIDED BY A…

Academic Pipeline and Futures Lab

DTIC Science & Technology

2016-02-01

AFRL-RY-WP-TR-2015-0186 ACADEMIC PIPELINE AND FUTURES LAB Brian D. Rigling Wright State University FEBRUARY 2016...DD-MM-YY) 2. REPORT TYPE 3. DATES COVERED (From - To) February 2016 Final 12 June 2009 – 30 September 2015 4. TITLE AND SUBTITLE ACADEMIC ...6 3 WSU ACADEMIC PIPELINE AND LAYERED SENSING FUTURES LAB (prepared by K

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Synthesis Condensed Matter and Materials Physics Scattering and Instrumentation Science Centers Center for materials and phenomena at multiple time and length scales. Through our core programs and research centers Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials

Towards a Manifesto for Living Lab Co-creation

NASA Astrophysics Data System (ADS)

Følstad, Asbjørn; Brandtzæg, Petter Bae; Gulliksen, Jan; Börjeson, Mikael; Näkki, Pirjo

There is a growing interest in Living Labs for innovation and development in the field of information and communication technology. In particular there seem to be a tendency that current Living Labs aim to involve users for co-creative purposes. However, the current literature on Living Lab co-creation is severely limited. Therefore an Interact workshop is arranged as a first step towards a manifesto for Living Lab co-creation.

DrImpute: imputing dropout events in single cell RNA sequencing data.

PubMed

Gong, Wuming; Kwak, Il-Youp; Pota, Pruthvi; Koyano-Nakagawa, Naoko; Garry, Daniel J

2018-06-08

The single cell RNA sequencing (scRNA-seq) technique begin a new era by allowing the observation of gene expression at the single cell level. However, there is also a large amount of technical and biological noise. Because of the low number of RNA transcriptomes and the stochastic nature of the gene expression pattern, there is a high chance of missing nonzero entries as zero, which are called dropout events. We develop DrImpute to impute dropout events in scRNA-seq data. We show that DrImpute has significantly better performance on the separation of the dropout zeros from true zeros than existing imputation algorithms. We also demonstrate that DrImpute can significantly improve the performance of existing tools for clustering, visualization and lineage reconstruction of nine published scRNA-seq datasets. DrImpute can serve as a very useful addition to the currently existing statistical tools for single cell RNA-seq analysis. DrImpute is implemented in R and is available at https://github.com/gongx030/DrImpute .

Lawrence Berkeley National Laboratory 2016 Annual Financial Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Williams, Kim, P.; Williams, Kim, P.

FY2016 was a year of significant change and progress at Berkeley Lab. In March, Laboratory Director Michael Witherell assumed his new role when former Lab Director Paul Alivisatos became Vice Chancellor for Research at UC Berkeley. Dr. Witherell has solidified the Lab’s strategy, with a focus on long term science and technology priorities. Large-scale science efforts continued to expand at the Lab, including the Dark Energy Spectroscopic Instrument now heading towards construction, and the LUX-ZEPLIN dark matter detector to be built underground in South Dakota. Another proposed project, the Advanced Light Source-Upgrade, was given preliminary approval and will be themore » Lab’s largest scientific investment in years. Construction of the Integrative Genomics Building began, and will bring together researchers from the Lab’s Joint Genome Institute, now based in Walnut Creek, and the Systems Biology Knowledgebase (K-Base) under one roof. Investment in the Lab’s infrastructure also continues, informed by the Lab’s Infrastructure Strategic Plan. Another important focus is on developing the next generation of scientists with the talent and diversity needed to sustain Berkeley Lab’s scientific leadership and mission contributions to DOE and the Nation. Berkeley Lab received $897.5M in new FY2016 funding, a 12.5% increase over FY2015, for both programmatic and infrastructure activities. While the Laboratory experienced a substantial increase in funding, it was accompanied by only a modest increase in spending, as areas of growth were partially offset by the completion of several major efforts in FY2015. FY2016 costs were $826.9M, an increase of 1.9% over FY2015. Similar to the prior year, the indirect-funded Operations units worked with generally flat budgets to yield more funding for strategic needs. A key challenge for Berkeley Lab continues to be achieving the best balance to fund essential investments, deliver highly effective operational mission support

NREL: News - Technology Review Honors National Renewable Energy Lab

Science.gov Websites

Engineer as One of the World's Top Young Innovators Technology Review Honors National Renewable Technology Magazine Golden, Colo., May 20, 2002 The U.S. Department of Energy's National Renewable Energy Systems, has been chosen as one of the world's 100 Top Young Innovators by Technology Review, MIT's

Dr. von Braun With Five of the Original Astronauts

NASA Technical Reports Server (NTRS)

1959-01-01

Five of the seven original astronauts are seen with Dr. von Braun inspecting the Mercury-Redstone hardware in the Fabrication Laboratory of Army Ballistic Missile Agency (ABMA) in 1959. Left to right: Astronauts Walter Schirra, Alan Shepard, John Glenn, Scott Carpenter, Gordon Cooper, and Dr. von Braun.

Berkeley Lab Sheds Light on Improving Solar Cell Efficiency

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawrence Berkeley National Laboratory

2007-07-20

Typical manufacturing methods produce solar cells with an efficiency of 12-15%; and 14% efficiency is the bare minimum for achieving a profit. In work performed at the Ernest Orlando Lawrence Berkeley National Laboratory (Berkeley, CA, 5 10-486-577 1)--a US Department of Energy national laboratory that conducts unclassified scientific research and is managed by the University of California--scientist Scott McHugo has obtained keen insights into the impaired performance of solar cells manufactured from polycrystalline silicon. The solar cell market is potentially vast, according to Berkeley Lab. Lightweight solar panels are highly beneficial for providing electrical power to remote locations in developingmore » nations, since there is no need to build transmission lines or truck-in generator fuel. Moreover, industrial nations confronted with diminishing resources have active programs aimed at producing improved, less expensive solar cells. 'In a solar cell, there is a junction between p-type silicon and an n-type layer, such as diffused-in phosphorous', explained McHugo, who is now with Berkeley Lab's Accelerator and Fusion Research Division. 'When sunlight is absorbed, it frees electrons, which start migrating in a random-walk fashion toward that junction. If the electrons make it to the junction; they contribute to the cell's output of electric current. Often, however, before they reach the junction, they recombine at specific sites in the crystal' (and, therefore, cannot contribute to current output). McHugo scrutinized a map of a silicon wafer in which sites of high recombination appeared as dark regions. Previously, researchers had shown that such phenomena occurred not primarily at grain boundaries in the polycrystalline material, as might be expected, but more often at dislocations in the crystal. However, the dislocations themselves were not the problem. Using a unique heat treatment technique, McHugo performed electrical measurements to investigate the

Molecular Foundry Workshop draws overflow crowd to BerkeleyLab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robinson, Art

2002-11-27

Nanoscale science and technology is now one of the top research priorities in the United States. With this background, it is no surprise that an overflow crowd or more than 350 registrants filled two auditoriums to hear about and contribute ideas for the new Molecular Foundry during a two-day workshop at the Lawrence Berkeley National Laboratory (Berkeley Lab). Scheduled to open for business at Berkeley Labin early 2006, the Molecular Foundry is one of three Nanoscale Science Research Centers (NSRCs) put forward for funding by the DOE's Office of Basic Energy Sciences (BES).

The research contributions of Dr. Paul Van Deusen

Treesearch

Thomas B. Lynch; Francis A. Roesch; John Paul McTague; Jeffrey H. Gove; Gregory A. Reams; Aaron R. Weiskittel

2015-01-01

Dr. Paul Van Deusen’s recent passing concluded a rich 30+-year research career dedicated to development and implementation of quantitative methods for forestry and natural resources. Since the early part of his career as a biometrician with the USDA Forest Service Southern Research Station in the 1980s-1990s and continuing with his later employment at NCASI, Dr. Van...

Berkeley Lab 2nd Grader Outreach

ScienceCinema

Scoggins, Jackie; Louie, Virginia

2017-12-11

The Berkeley Lab IT Department sponsored a community outreach program aimed at teaching young children about computers and networks. Second graders from LeConte Elementary School joined Lab IT Staff for a day of in-depth exercises and fun.

Labs: 1987.

ERIC Educational Resources Information Center

Igelsrud, Don, Ed.

1988-01-01

This article presents a variety of topics discussed in this column and at a biology teachers' workshop concerning the quality and value of lab techniques used for teaching high school biology. Topics included are Drosophila salivary glands, sea urchins, innovations, dyes and networking. (CW)

Berkeley Lab - Materials Sciences Division

Science.gov Websites

-486-6999 Urgent Radiation Protection Group Assistance Non-Life Threatening Event 24/7 Lab Phone: x7277 : 911 (no extentions required now) Non-Emergency Reporting (Fire and Police) Non-Life Threatening Event Spill Non-Life Threatening Event 24/7 Lab Phone: x6999 Cell Phone: 510-486-6999 Off Site Locations: 510

Report from the banding lab

USGS Publications Warehouse

Tautin, J.

1995-01-01

Mr. Tautin reported on the seemingly everchanging structure of biological science units within the Interior Department. Current Congressional proposals would either change the name of the Bird Banding Lab's parent agency or make it part of the Geological Survey. The current Congress has not looked favorably on science budgets within the Interior Department, and the Banding Lab's budget is being squeezed ever tighter.

Early onset of diabetes in the proband is the major determinant of risk in HLA DR3-DQ2/DR4-DQ8 siblings.

PubMed

Gillespie, Kathleen M; Aitken, Rachel J; Wilson, Isabel; Williams, Alistair J K; Bingley, Polly J

2014-03-01

Islet autoimmunity is initiated in infancy, and primary prevention trials require children at high genetic risk to be identified before autoantibodies appear. To inform screening strategies, we evaluated risks of autoimmunity and diabetes associated with HLA DR3-DQ2/DR4-DQ8 in U.K. families. Extended HLA haplotypes were determined in 2,134 siblings from the Bart's-Oxford Study followed to a median age of 22 years. Risks of diabetes and islet autoimmunity (more than two antibodies) were estimated by survival analysis. Of 138 informative DR3-DQ2/DR4-DQ8 siblings, 63% shared both haplotypes with their diabetic proband, 29% shared one, and 8% shared neither. In HLA-identical DR3-DQ2/DR4-DQ8 siblings, the cumulative risk of diabetes by age 15 was 17% (vs. 6% in those sharing one haplotype or none; P = 0.095). Risk varied, however, with the age at the onset of diabetes in the proband; the cumulative risk of autoimmunity and/or diabetes by age 15 was 61% in siblings of probands diagnosed when younger than 10 years old compared with only 4.7% in those diagnosed after age 10 years (P < 0.001). The age of the proband at diagnosis, but not HLA haplotype sharing, was an independent determinant of sibling risk. This suggests that non-HLA genes or epigenetic/environmental factors that accelerate the progression of type 1 diabetes in the proband strongly affect risk in siblings.

Computer-based Astronomy Labs for Non-science Majors

NASA Astrophysics Data System (ADS)

Smith, A. B. E.; Murray, S. D.; Ward, R. A.

1998-12-01

We describe and demonstrate two laboratory exercises, Kepler's Third Law and Stellar Structure, which are being developed for use in an astronomy laboratory class aimed at non-science majors. The labs run with Microsoft's Excel 98 (Macintosh) or Excel 97 (Windows). They can be run in a classroom setting or in an independent learning environment. The intent of the labs is twofold; first and foremost, students learn the subject matter through a series of informational frames. Next, students enhance their understanding by applying their knowledge in lab procedures, while also gaining familiarity with the use and power of a widely-used software package and scientific tool. No mathematical knowledge beyond basic algebra is required to complete the labs or to understand the computations in the spreadsheets, although the students are exposed to the concepts of numerical integration. The labs are contained in Excel workbook files. In the files are multiple spreadsheets, which contain either a frame with information on how to run the lab, material on the subject, or one or more procedures. Excel's VBA macro language is used to automate the labs. The macros are accessed through button interfaces positioned on the spreadsheets. This is done intentionally so that students can focus on learning the subject matter and the basic spreadsheet features without having to learn advanced Excel features all at once. Students open the file and progress through the informational frames to the procedures. After each procedure, student comments and data are automatically recorded in a preformatted Lab Report spreadsheet. Once all procedures have been completed, the student is prompted for a filename in which to save their Lab Report. The lab reports can then be printed or emailed to the instructor. The files will have full worksheet and workbook protection, and will have a "redo" feature at the end of the lab for students who want to repeat a procedure.

Ground-Based Missile Defense (National Missile Defense): Is It Feasible?

DTIC Science & Technology

2004-03-19

Westview Press), 191. 47 Ibid. 192. 48 Dr. Nicholas Berry, National Missile Defense: What Does It All Mean ? National Missile Defense: Views from Asia...153. 18 19 BIBLIOGRAPHY Berry, Nicholas. National Missile Defense: What Does It All Mean ? National Missile Defense: Views from Asia, Center for

Evaluation of oral microbiology lab curriculum reform.

PubMed

Nie, Min; Gao, Zhen Y; Wu, Xin Y; Jiang, Chen X; Du, Jia H

2015-12-07

According to the updated concept of oral microbiology, the School of Stomatology, Wuhan University, has carried out oral microbiology teaching reforms during the last 5 years. There was no lab curriculum before 2009 except for a theory course of oral microbiology. The school has implemented an innovative curriculum with oral medicine characteristics to strengthen understanding of knowledge, cultivate students' scientific interest and develop their potential, to cultivate the comprehensive ability of students. This study was designed to evaluate the oral microbiology lab curriculum by analyzing student performance and perceptions regarding the curriculum from 2009 to 2013. The lab curriculum adopted modalities for cooperative learning. Students collected dental plaque from each other and isolated the cariogenic bacteria with selective medium plates. Then they purified the enrichment culture medium and identified the cariogenic strains by Gram stain and biochemical tests. Both quantitative and qualitative data for 5 years were analysed in this study. Part One of the current study assessed student performance in the lab from 2009 to 2013. Part Two used qualitative means to assess students' perceptions by an open questionnaire. The 271 study students' grades on oral microbiology improved during the lab curriculum: "A" grades rose from 60.5 to 81.2 %, and "C" grades fell from 28.4 to 6.3 %. All students considered the lab curriculum to be interesting and helpful. Quantitative and qualitative data converge to suggest that the lab curriculum has strengthened students' grasp of important microbiology-related theory, cultivated their scientific interest, and developed their potential and comprehensive abilities. Our student performance and perception data support the continued use of the innovative teaching system. As an extension and complement of the theory course, the oral microbiology lab curriculum appears to improve the quality of oral medicine education and help to

My Green Car: Painting Motor City Green (Ep. 2) – DOE Lab-Corps Video Series

ScienceCinema

Saxena, Samveg; Shah, Nihar; Hansen, Dana

2018-06-12

The Lab’s MyGreenCar team kicks off its customer discovery process in Detroit with a business boot camp designed for scientists developing energy-related technologies. Customer interviews lead to late night discussions and insights on less-than-receptive consumers. Back in Berkeley, the team decides to fine tune targeted customer segments. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates for consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.

Dr. Robert Goddard

NASA Image and Video Library

2017-12-08

Dr. Robert Goddard's 22 foot rocket in it's launching tower, 1940, near Roswell, New Mexico. N.T. Ljungquist on the ground, A.W. Kisk working on rocket and C. Mansur at top of tower. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

Proceedings and Minutes of the National Interagency Coordination Group Meeting - Low Altitude Direct Strike Lightning Characterization Program Held in Saint Louis, Missouri on 28-29 January 1985.

DTIC Science & Technology

1985-09-01

Gallon External Fuel Tank. a. This is a filament-wound fuel tank with nomex honeycomb core, inner layers of Kevlar and glass , outer layers of...MD 20910 Dr. A. Carro FAA Technical Center Mr. Jack Lippert ACT-340 AFWAL/FIEA Atlantic City Airport, NJ 08405 Air Force Wright Aeronautical Lab

LABS Foundational Technology

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olson, Jerry

2012-01-01

They are the inventors of our generation dedicated to exceptional science, advancing the technologies of tomorrow. CO-LABS honors the outstanding achievements of researchers and their impact on the world.

NLRP1 deficiency attenuates diabetic retinopathy (DR) in mice through suppressing inflammation response.

PubMed

Li, Yan; Liu, Chang; Wan, Xin-Shun; Li, Shao-Wei

2018-06-22

Diabetic retinopathy (DR) is the common cause of diabetic vascular complications. The NOD-like receptor (NLR) family, pyrin domain containing 1 (NLRP1), also known as NALP1, inflammasome is the first member of the NLR family to be discovered, playing an important role in inflammatory response. However, its effect on DR development has not been reported. In the study, the wild type (WT) and NLRP1 -/- mice were injected with streptozotocin (STZ) to induce DR. The results indicated that NLRP1 -/- significantly increased bodyweight reduction and decreased blood glucose levels induced by STZ. WT/DR mice exhibited higher levels of NLRP1 in retinas. NLRP1 -/- ameliorated retinal abnormalities in DR mice using H&E staining. In addition, attenuated avascular areas and neovascular tufts were also observed in NLRP1 -/- /DR mice. The levels of pro-inflammatory cytokines in serum and retinas were highly induced in WT/DR mice, whereas being markedly reduced by NLRP1 -/- . In addition, vascular endothelial growth factor (VEGF) and Iba1 expressions induced by STZ in serum or retinas were significantly down-regulated in NLRP1 -/- /DR mice. Consistently, NLRP1 -/- attenuated ASC and Caspase-1 expressions in retinas of DR mice. Compared to WT/DR group, NLRP1 -/- markedly decreased retina p-nuclear factor-κB (NF-κB), interleukin-1β (IL-1β) and IL-18 levels. And similar results were confirmed in vitro that suppressing NLRP1/ASC inflammasome ameliorated inflammatory response in fructose-treated retinal ganglion cells. The results above indicated that the modulation of NLRP1 inflammasome might be a promising strategy for DR therapy. Copyright © 2018. Published by Elsevier Inc.

Frederick National Lab's Contribution to ATOM | FNLCR Staging

Cancer.gov

As a founding member organization of ATOM, the Frederick National Labwill contribute scientific expertise in precision oncology, computational chemistry and cancer biology, as well as support for open sharing of data sets and predictive modelin

1984 Program Report on the Army-Navy Initiative in the National Capital Area in Support of the Department of Defense Science and Engineering Apprenticeship Program for High School Students

DTIC Science & Technology

1985-03-01

Mexico . The other method was by the Faraday Rotation Principle calculated by polarimeter here at the lab. To measure the TEC by either method gives a base...shock in chronic rats. Springbrook High School Montgomery County, Md. Sarah Gaffen Investigated the herpes Varicella Mentor: Dr. John Hay Zoster virus

Berkeley Lab - Materials Sciences Division

Science.gov Websites

Berkeley Lab Berkeley Lab A-Z Index Phone Book Jobs Search DOE Search MSD Go MSD - Materials Investigators Ager, Joel W » Alivisatos, A Paul » Altman, Ehud » Analytis, James » Anderson, Christopher  , Naomi » Gullikson, Eric M » Harris, Stephen J » Hasan, M. Zahid » Hellman, Frances » Helms, Brett A

Experiential Learning of Digital Communication Using LabVIEW

ERIC Educational Resources Information Center

Zhan, Wei; Porter, Jay R.; Morgan, Joseph A.

2014-01-01

This paper discusses the design and implementation of laboratories and course projects using LabVIEW in an instrumentation course. The pedagogical challenge is to enhance students' learning of digital communication using LabVIEW. LabVIEW was extensively used in the laboratory sessions, which better prepared students for the course projects. Two…

A Further Characterization of Empirical Research Related to Learning Outcome Achievement in Remote and Virtual Science Labs

NASA Astrophysics Data System (ADS)

Brinson, James R.

2017-10-01

This paper further characterizes recently reviewed literature related to student learning outcome achievement in non-traditional (virtual and remote) versus traditional (hands-on) science labs, as well as factors to consider when evaluating the state and progress of research in this field as a whole. Current research is characterized according to (1) participant nationality and culture, (2) participant education level, (3) participant demography, (4) scientific discipline, and (5) research methodology, which could provide avenues for further research and useful dialog regarding the measurement and interpretation of data related to student learning outcome achievement in, and thus the efficacy of, non-traditional versus traditional science labs. Current research is also characterized by (6) research publication media and (7) availability of non-traditional labs used, which demonstrate some of the obstacles to progress and consensus in this research field.

My Green Car: Taking it to the Streets (Ep. 3) – DOE Lab-Corps Video Series

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saxena, Samveg; Shah, Nihar; Hansen, Dana

The researcher team finds enthusiastic consumers at familiar Berkeley hangouts. Then Industry Mentor Russell Carrington pushes the group to consider who will pay for the information the fuel economy app provides. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates for consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-fundedmore » program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.« less

VizieR Online Data Catalog: Gaia DR1 (Gaia Collaboration, 2016)

NASA Astrophysics Data System (ADS)

Gaia Collaboration

2016-06-01

Gaia DR1 is based on observations collected between 25 July 2014 and 16 September 2015. Gaia DR1 contains positions (RA,DE) and G magnitudes for all sources with acceptable formal standard errors on positions. Positions and individual uncertainties are computed using a generic prior and Bayes' rule (detailed description in "Gaia astrometry for stars with too few observations. A Bayesian approach", Michalik et al., 2015A&A...583A..68M). The five-parameter astrometric solution - positions, parallaxes, and proper motions - for stars in common between the Tycho-2 Catalogue and Gaia is contained in Gaia DR1. This part of Gaia DR1 is based on the Tycho-Gaia Astrometric Solution (paper with detailed description (Michalik et al., 2015A&A...574A.115M); paper describing theory and background (Michalik et al., 2014A&A...571A..85M); paper describing quasar extension (Michalik & Lindegren, 2016A&A...586A..26M)). At the beginning of the routine phase, for a period of 4 weeks, a special scanning mode repeatedly covering the ecliptic poles on every spin was executed for calibration purposes. Photometric data of selected RR Lyrae and Cepheid variable stars based on these high-cadence measurements are contained in Gaia DR1. Positions (RA,DE) and G magnitudes for 2152 ICRF quasars (F. Mignard et al., 2016, A&A, in press.). The Gaia Archive DR1 data is available at archives.esac.esa.int/gaia. Tgas and Gaia Sources can be downloaded as VOTables, FITS or CSV at http://cdn.gea.esac.esa.int/Gaia/ If you use public Gaia DR1 data in your paper, please take note of our guide on how to acknowledge and cite Gaia DR1: http://gaia.esac.esa.int/documentation/GDR1/Miscellaneous/\\ seccreditandcitationinstructions.html (9 data files).

Practical Physics Labs: A Resource Manual.

ERIC Educational Resources Information Center

Goodwin, Peter

This resource manual focuses on physics labs that relate to the world around us and utilize simple equipment and situations. Forty-five laboratories are included that relate to thermodynamics, electricity, magnetism, dynamics, optics, wave transmission, centripetal force, and atomic physics. Each lab has three sections. The first section…

My Green Car: Painting Motor City Green (Ep. 2) – DOE Lab-Corps Video Series

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saxena, Samveg; Shah, Nihar; Hansen, Dana

The Lab’s MyGreenCar team kicks off its customer discovery process in Detroit with a business boot camp designed for scientists developing energy-related technologies. Customer interviews lead to late night discussions and insights on less-than-receptive consumers. Back in Berkeley, the team decides to fine tune targeted customer segments. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimatesmore » for consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.« less

Meeting in San Francisco: Integrated Disinfection By-Products Mixtures Research: Results from the Four Lab Study

EPA Science Inventory

This study involves the collaboration of the four national laboratories of the U.S. Environmental Protection Agency (EPA), as well as other scientists from universities and water utilities, and is termed the ‘Four Lab Study’. The purpose of this study is to address concerns rela...

Baseball Physics: A New Mechanics Lab

NASA Astrophysics Data System (ADS)

Wagoner, Kasey; Flanagan, Daniel

2018-05-01

The game of baseball provides an interesting laboratory for experimenting with mechanical phenomena (there are many good examples in The Physics Teacher, available on Professor Alan Nathan's website, and discussed in Physics of Baseball & Softball). We have developed a lab, for an introductory-level physics course, that investigates many of these phenomena. The lab uses inexpensive, readily available equipment such as wooden baseball bats, baseballs, and actual Major League Baseball data. By the end of the lab, students have revisited many concepts they learned earlier in the semester and come away with an understanding of how to put seemingly disparate ideas together to analyze a fun sport.

Teaching Chemistry Lab Safety through Comics

NASA Astrophysics Data System (ADS)

di Raddo, Pasquale

2006-04-01

As a means for raising students' interest in aspects pertaining to chemistry lab safety, this article presents a novel approach to teaching this important subject. Comic book lab scenes that involve fictional characters familiar to many students are presented and discussed as to the safety concerns represented in those images. These are discussed in a safety prelab session. For the sake of comparison, students are then shown images taken from current chemistry journals of safety-conscious contemporary chemists at work in their labs. Finally the need to adhere to copyright regulations for the use of the images is discussed so as to increase students' awareness of academic honesty and copyright issues.

Dr. Jacob Cohen presents the H. Julian Allen award to Anthony Colaprete.

NASA Image and Video Library

2017-03-16

Dr. Jacob Cohen Director Office of Chief Scientist with Dr. Anthony Colaprete recipient of the H. Julian Allen Award In recognition as co-author of the outstanding scientific paper entitled "Detection of Water in the LCROSS Ejecta Pluma." Shown here Dr. Jacob Cohen presents the H. Julian Allen award to Anthony Colaprete.

LLNL: Science in the National Interest

ScienceCinema

George Miller

2017-12-09

This is Lawrence Livermore National Laboratory. located in the Livermore Valley about 50 miles east of San Francisco, the Lab is where the nations topmost science, engineering and technology come together. National security, counter-terrorism, medical technologies, energy, climate change our researchers are working to develop solutions to these challenges. For more than 50 years, we have been keeping America strong.

DR AVRAM JOZEF VINAVER (1862-1915) - PIONEER OF RADIOLOGY IN SERBIA.

PubMed

Babić, Rade Radomir; Stanković Babić, Gordana

2015-01-01

Dr Abraham Joseph Vinaver (1862-1915), a Jew from Poland, was a pioneer of radiology in Serbia. He graduated from the Faculty of Medicine in Warsaw (1887), but lived and worked in abac (the Kingdom of Serbia) since 1890. Dr Abraham Joseph Vinarev - Career Development. He procured the first X-ray machine and developed radiological service in Sabac five years after the discovery of X-rays. These were the beginnings of radiology in Serbia. He introduced the application of artesian wells. Dr Abraham Joseph Vinarev - a Participant at the First Congress of Serbian Physicians and Naturalists, Belgrade 1904. "The diagnostic importance of X-rays in lung disease, especially in initial tuberculosis" and "Five Years of Treatment by X-Ray Machines" were the first works in the field of radiology in Serbia by this author. Dr Abraham Joseph Vinaver - Reserve Medical Officer in the Serbian Army. During the Balkan Wars, he was a volunteer with the rank of major engaged in military corps and he participated in the First World War as well. He died of malaria in 1915 in Gevgelija. "Dr Avram Vinaver"- Stanislav Vinarev. His dedication to work during the typhus epidemics was put into verses of a poem by his son Stanislav Vinarev. Dr Avram Vinaver Joseph was a noble man with a great heart, who selflessly sacrificed himself for the Serbian people and Serbia. He gave his contribution to the development of health services in Serbia, both in peacetime and wartime conditions. Dr Abraham Joseph Vinaver laid the foundations for today's radiology in Serbia.

Special issue dedicated in memory of Dr. Edward H. Ahrens, Jr.

PubMed

Ahrens, Edward H

2002-01-01

This special issue of the "Cardiovascular Drug Reviews" is dedicated in memory of Dr. Edward H. Ahrens, Jr., who died on Dec. 9th, 2000 at the Princeton Medical Center in New Jersey at the age of 85. Dr. Ahrens was the Director of the Lipid Metabolism Laboratory at the Rockefeller University. Dr. Alexander Scriabine conceived the idea for the issue at the special memorial symposium held at the Rockefeller University on Feb. 05, 2002 under the auspices of The New York Lipid and Vascular Biology Research Club. Dr. Ahrens was the first president of the club. He started this club with Drs. Howard Eder and DeWitt Goodman. Dr. Eder thought that it would be a fitting attribute to honor one of the founding fathers of the club by hosting a memorial symposium. I, as the President of the club for that academic year, had no hesitation in accepting the proposal. This year will be the 40th anniversary of the club and its continued success provides a glimpse of the fine legacy left behind by Dr. Ahrens. Dr. Ahrens also played a pivotal role in the establishment of the Journal of Lipid Research. This is the 43rd year of the journal and in this commemorative issue we are reproducing a review he wrote for the 25th anniversary of the journal. I was never personally acquainted with Dr. Ahrens. However, I am honored that I got this opportunity to pay tribute to a great scientist whose work has contributed immensely to the progress of lipid research. He was a person who touched many lives and still continues to do so. My involvement in the remembrance of Dr. Ahrens shows that science not only impacts your contemporaries but also generations that follow you. Scientific research is a journey where you can leave your trails behind and be remembered for your work long after your departure from this world. Dr. Ahrens contributed immensely to the understanding of cholesterol metabolism. In the early stages of his career he showed that phospholipids solubilize fat in the blood. Now we know

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

The Goddard Space Flight Center was named in honor of Dr. Robert Goddard, a pioneer in rocket development. Dr. Goddard received patents for a multi-stage rocket and liquid propellants in 1914 and published a paper describing how to reach extreme altitudes six years later. That paper, "A Method of Reaching Extreme Altitudes," detailed methods for raising weather-recording instruments higher than what could be achieved by balloons and explained the mathematical theories of rocket propulsion. The paper, which was published by the Smithsonian Institution, also discussed the possibility of a rocket reaching the moon-a position for which the press ridiculed Goddard. Yet several copies of the report found their way to Europe, and by1927, the German Rocket Society was established, and the German Army began its rocket program in 1931. Goddard, meanwhile, continued his work. By 1926, he had constructed and tested the first rocket using liquid fuel. Goddard's work largely anticipated in technical detail the later German V-2 missiles, including gyroscopic control, steering by means of vanes in the jet stream of the rocket motor, gimbal-steering, power-driven fuel pumps and other devices. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

76 FR 52548 - National Veterinary Accreditation Program; Currently Accredited Veterinarians Performing...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-23

.... APHIS-2006-0093] RIN 0579-AC04 National Veterinary Accreditation Program; Currently Accredited... accredited in the National Veterinary Accreditation Program (NVAP) may continue to perform accredited duties..., 2011. FOR FURTHER INFORMATION CONTACT: Dr. Todd Behre, National Veterinary Accreditation Program, VS...

DR-induced escape of O and C from early Mars

NASA Astrophysics Data System (ADS)

Zhao, Jinjin; Tian, Feng; Ni, Yufang; Huang, Xiaomeng

2017-03-01

Energetic particles produced in Dissociative recombination (DR) reactions could escape planets with low gravity, such as Mars, if they could overcome collisions with the surrounding background gases. In this work, a 3-D Monte Carlo model is developed to study these photochemical escape processes on early Mars. Although the DR reaction rates of O2+, CO2+, and CO+ increase monotonically with solar soft X-ray and extreme ultraviolet (XUV) flux, the peak of the calculated DR-induced escape rates of O is near 3 × XUV, and the DR-induced escape rates of C increase with XUV until 10 × XUV. The non-monotonic behavior can be explained by the increased column densities of background species in high XUV conditions, which can deflect energetic particles through collisions more efficiently. At 20 × XUV, CO+ DR is the main source of escaping O and C, and the escape of secondary particles could contribute to 30∼40% and 10% of the total escape of O and C respectively. The time-integrated DR-induced escape of O and C is equivalent to 1 m of H2O and 20 mbar of CO2 escaping early Mars since 4.5 billion years ago. The accumulated CO2 loss is much lower than what's needed to explain the carbon isotopic ratios on Mars and much lower than the total CO2 needed to warm up early Mars. If more vigorous escape mechanisms were absent on early Mars, substantial inventories of volatiles have not been detected yet.

Hydrogel Beads: The New Slime Lab?

ERIC Educational Resources Information Center

Brockway, Debra; Libera, Matthew; Welner, Heidi

2011-01-01

Creating slime fascinates students. Unfortunately, though intrigue is at its peak, the educational aspect of this activity is often minimal. This article describes a chemistry lab that closely relates to the slime lab and allows high school students to explore the concepts of chemical bonding, properties, and replacement reactions. It involves the…

Interactive, Online, Adsorption Lab to Support Discovery of the Scientific Process

NASA Astrophysics Data System (ADS)

Carroll, K. C.; Ulery, A. L.; Chamberlin, B.; Dettmer, A.

2014-12-01

Science students require more than methods practice in lab activities; they must gain an understanding of the application of the scientific process through lab work. Large classes, time constraints, and funding may limit student access to science labs, denying students access to the types of experiential learning needed to motivate and develop new scientists. Interactive, discovery-based computer simulations and virtual labs provide an alternative, low-risk opportunity for learners to engage in lab processes and activities. Students can conduct experiments, collect data, draw conclusions, and even abort a session. We have developed an online virtual lab, through which students can interactively develop as scientists as they learn about scientific concepts, lab equipment, and proper lab techniques. Our first lab topic is adsorption of chemicals to soil, but the methodology is transferrable to other topics. In addition to learning the specific procedures involved in each lab, the online activities will prompt exploration and practice in key scientific and mathematical concepts, such as unit conversion, significant digits, assessing risks, evaluating bias, and assessing quantity and quality of data. These labs are not designed to replace traditional lab instruction, but to supplement instruction on challenging or particularly time-consuming concepts. To complement classroom instruction, students can engage in a lab experience outside the lab and over a shorter time period than often required with real-world adsorption studies. More importantly, students can reflect, discuss, review, and even fail at their lab experience as part of the process to see why natural processes and scientific approaches work the way they do. Our Media Productions team has completed a series of online digital labs available at virtuallabs.nmsu.edu and scienceofsoil.com, and these virtual labs are being integrated into coursework to evaluate changes in student learning.

The Pyramid Liner Concept

DTIC Science & Technology

2003-06-01

Albuquerque, NM, 1992. Dobratz, B. M. LLNL Explosives Handbook; UCRL -5299; Lawrence Livermore Laboratory: Livermore, CA, 1981 Geiger, W.; Honcia, G...L.; Hornig, H. C.; Kury, J. W. Adiabatic Expansion of High Explosive Detonation Products; UCRL -50422; Lawrence Livermore National Laboratory...ARMAMENT LAB AFATL DLJR J FOSTER D LAMBERT EGLIN AFB FL 32542-6810 2 DARPA W SNOWDEN S WAX 3701 N FAIRFAX DR ARLINGTON VA

Bituminous Mixtures Lab

DOT National Transportation Integrated Search

2002-07-25

The Bituminous Mixtures Laboratory (BML) specializes in the research of asphalt pavement mixtures. This lab supports FHWA's efforts to develop, evaluate and improve materials, mixture design technology and performance-based tests for asphalt paving m...

Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis

NASA Technical Reports Server (NTRS)

Lewis, Cathleen; Wright, Rebecca

2012-01-01

Dr. Cathleen Lewis was interviewed by Rebecca Wright during the presentation of an "Interview with Smithsonian NASM Spacesuit Curator Dr. Cathleen Lewis" on May 14, 2012. Topics included the care, size, and history of the spacesuit collection at the Smithsonian and the recent move to the state-of-the-art permanent storage facility at the Udvar-Hazy facility in Virginia.

Seeing an Old Lab in a New Light: Transforming a Traditional Optics Lab into Full Guided Inquiry

ERIC Educational Resources Information Center

Maley, Tim; Stoll, Will; Demir, Kadir

2013-01-01

This paper describes the authors' experiences transforming a "cookbook" lab into an inquiry-based investigation and the powerful effect the inquiry-oriented lab had on our students' understanding of lenses. We found the inquiry-oriented approach led to richer interactions between students as well as a deeper conceptual…

Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

NASA Technical Reports Server (NTRS)

1967-01-01

Marshall Space Flight Center (MSFC) Director, Dr. von Braun, submerges after spending some time under water in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

GeoLab: A Geological Workstation for Future Missions

NASA Technical Reports Server (NTRS)

Evans, Cynthia; Calaway, Michael; Bell, Mary Sue; Li, Zheng; Tong, Shuo; Zhong, Ye; Dahiwala, Ravi

2014-01-01

The GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance theThe GeoLab glovebox was, until November 2012, fully integrated into NASA's Deep Space Habitat (DSH) Analog Testbed. The conceptual design for GeoLab came from several sources, including current research instruments (Microgravity Science Glovebox) used on the International Space Station, existing Astromaterials Curation Laboratory hardware and clean room procedures, and mission scenarios developed for earlier programs. GeoLab allowed NASA scientists to test science operations related to contained sample examination during simulated exploration missions. The team demonstrated science operations that enhance the early scientific returns from future missions and ensure that the best samples are selected for Earth return. The facility was also designed to foster the development of instrument technology. Since 2009, when GeoLab design and construction began, the GeoLab team [a group of scientists from the Astromaterials Acquisition and Curation Office within the Astromaterials Research and Exploration Science (ARES) Directorate at JSC] has progressively developed and reconfigured the GeoLab hardware and software interfaces and developed test objectives, which were to 1) determine requirements and strategies for sample handling and prioritization for geological operations on other planetary surfaces, 2) assess the scientific contribution of selective in-situ sample

Extending ORAC-DR for Offline Processing of ESO, INGRID, and Classic Cam data

NASA Astrophysics Data System (ADS)

Currie, M. J.

2004-07-01

ORAC-DR--a flexible reduction pipeline---was originally developed by the Joint Astronomy Centre for real-time inspection of reduced data at its telescopes. Starlink is extending ORAC-DR to process at home institutions data from other observatories, notably ESO, whose instruments make no provision for ORAC-DR. I outline the problems encountered and solutions implemented or proposed to apply ORAC-DR to the infra-red instruments ISAAC, NACO, INGRID, and Classic~Cam.

The Dominican Republic-Central American Free Trade Agreement (DR-CAFTA): Understanding the Reasons Why the Dominican Republic (DR) Joined the CAFTA Negotiations

DTIC Science & Technology

2009-06-01

the major issues that the DR faced was how to protect itself from imported U.S. beverages that contained high fructose corn syrup . Many Dominican... corn syrup as a sweetener.204 This was a controversial move, which gained support in the DR Congress after many sugar producers demanded increased...protection from foreign imports. The producers claimed that the introduction of imported corn syrup sweetened beverages would cause an approximate

A Medipix3 readout system based on the National Instruments FlexRIO card and using the LabVIEW programming environment

NASA Astrophysics Data System (ADS)

Horswell, I.; Gimenez, E. N.; Marchal, J.; Tartoni, N.

2011-01-01

Hybrid silicon photon-counting detectors are becoming standard equipment for many synchrotron applications. The latest in the Medipix family of read-out chips designed as part of the Medipix Collaboration at CERN is the Medipix3, which while maintaining the same pixel size as its predecessor, offers increased functionality and operating modes. The active area of the Medipix3 chip is approx 14mm × 14mm (containing 256 × 256 pixels) which is not large enough for many detector applications, this results in the need to tile many sensors and chips. As a first step on the road to develop such a detector, it was decided to build a prototype single chip readout system to gain the necessary experience in operating a Medipix3 chip. To provide a flexible learning and development tool it was decided to build an interface based on the recently released FlexRIOTM system from National Instruments and to use the LabVIEWTM graphical programming environment. This system and the achieved performance are described in this paper.

DR-induced Hot Oxygen and Carbon Coronae of Early Mars

NASA Astrophysics Data System (ADS)

Zhao, J.; Chassefiere, E.; Tian, F.; Chaufray, J. Y.; Leblanc, F.

2017-12-01

The evolution of Martian atmosphere is a key aspect to understand the habitability of Mars in time. The distributions of neutral atoms above the exobase of ancient Mars (corona) is important for understanding the interactions between the corona and the solar wind, which could help improving our understanding of the evolution of Martian atmosphere. In this work, a 3-D Monte Carlo Model is built to simulate Martian corona in different period of Mars history based on thermosphere structure corresponding to 1, 3, 10, and 20 times present solar XUV conditions and dissociative recombination (DR) reaction profiles. DR reactions of O2+, CO2+, and CO+ are considered as the sources of primary O and C. Secondary O and C atoms, which are formed through collisions between primaries and background species. We will discuss the dependence of physical properties of Martian corona as functions of solar XUV flux and DR reactions. We will also discuss the potential importance of CO+ DR as a contributor to Martian corona.

The Final Kepler Planet Candidate Catalog (DR25)

NASA Astrophysics Data System (ADS)

Coughlin, Jeffrey; Thompson, Susan E.; Kepler Team

2017-06-01

We present Kepler's final planet candidate catalog, which is based on the Q1--Q17 DR25 data release and was created to allow for accurate calculations of planetary occurrence rates. We discuss improvements made to our fully automated candidate vetting procedure, which yields specific categories of false positives and a disposition score value to indicate decision confidence. We present the use of light curve inversion and scrambling, in addition to our continued use of pixel-level transit injection, to produce artificial planet candidates and false positives. Since these simulated data sets were subjected to the same automated vetting procedure as the real data set, we are able to measure both the completeness and reliability of the catalog. The DR25 catalog, source code, and a multitude of completeness and reliability data products are available at the Exoplanet Archive (http://exoplanetarchive.ipac.caltech.edu). The DR25 light curves and pixel-level data are available at MAST (http://archive.stsci.edu/kepler).

Dr. Israel Cuellar (1946-2008)

ERIC Educational Resources Information Center

Zamarripa, Manuel X.

2009-01-01

On September 7th, 2008, the mental health field lost a trailblazing researcher and clinician as he lost his battle with amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig's disease. Dr. Israel Cuellar made significant contributions to the study of acculturation including its importance in delivering appropriate mental health…

Supercharging Lessons with a Virtual Lab

ERIC Educational Resources Information Center

Stewart, Jefferson; Vincent, Daniel

2013-01-01

The authors describes their experiences incorporating the virtual lab into a simple circuit lesson during an energy unit in a sixth-grade class. The lesson included a hands-on group experiment using wire, batteries, and light bulbs to make a circuit and an online simulation, using a virtual lab. Class discussions, student inquiries, and the study…

Magnetic Viscous Drag for Friction Labs

ERIC Educational Resources Information Center

Gaffney, Chris; Catching, Adam

2016-01-01

The typical friction lab performed in introductory mechanics courses is usually not the favorite of either the student or the instructor. The measurements are not all that easy to make, and reproducibility is usually a troublesome issue. This paper describes the augmentation of such a friction lab with a study of the viscous drag on a magnet…

Proceedings of a symposium on the elements of a national energy policy and dedication of Raymond C. Moore Hall, September 28--29, 1973

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waldron, G.A.

1973-01-01

The symposium was convened to dedicate the new Kansas Geological Survey building at the University of Kansas and conduct an exchange of ideas on the elements of a national energy policy. Dr. William W. Hambleton presented the introductory speech. Papers presented were: The elements of a national energy policy, Merrill W. Haas; A national energy policy - what should it include, Dr. Wilson M. Laird; Elements of a national energy policy, John D. Emerson, National energy policy and environmental quality, Dr. Beatrice E. Willard; Energy and the environment, Jerome H. Svore; A congressional point of view on energy policy, Senatormore » Clifford P. Hansen; and The time element in a national energy policy, Governor Robert D. Ray of Iowa. The dedication program followed. (MCW)« less

Berkeley Lab Scientist Named MacArthur "Genius" Fellow for Audio

Science.gov Websites

Preservation Research | Berkeley Lab Berkeley Lab A-Z Index Directory Submit Web People Navigation Berkeley Lab Search Submit Web People Close About the Lab Leadership/Organization Calendar News to digitally recover a 128-year-old recording of Alexander Graham Bell's voice, enabling people to

Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and

Science.gov Websites

Thermal Engineering Sciences | NREL Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and Thermal Engineering Sciences Dr. Johney Green Jr. - Associate Laboratory Director for Mechanical and Thermal Engineering Sciences A photo of Johney Green In his role, Johney Green oversees early

The Extended Core Coax: A novel nanoarchitecture for lab-on-a-chip electrochemical diagnostics

NASA Astrophysics Data System (ADS)

Valera, Amy E.; D'Imperio, Luke; Burns, Michael J.; Naughton, Michael J.; Chiles, Thomas C.

We report a novel nanoarchitecture, the Extended Core Coax (ECC) that has applicability for the detection of biomarkers in lab-on-a-chip diagnostic devices. ECC is capable of providing accessible, highly sensitive, and specific disease diagnosis at point-of-care. The architecture represents a vertically oriented nanocoax comprised of a gold inner metal core that extends 200nm above a chrome outer metal shield, separated by a dielectric annulus. Each ECC chip contains 7 discrete sensing arrays, 0.49 mm2 in size, containing 35,000 nanoscale coaxes wired in parallel. Previous non-extended nanocoaxial architectures have demonstrated a limit of detection (LOD) of 2 ng/mL of cholera toxin using an off-chip setup. This sensitivity compares favorably to the standard optical ELISA used in clinical settings. The ECC matches this LOD, and additionally offers the benefit of specific and reliable biofunctionalization on the extended gold core. Thus, the ECC is an attractive candidate for development as a full lab-on-a-chip biosensor for detection of infectious disease biomarkers, such as cholera toxin, through tethering of biomarker recognition proteins, such as antibodies, directly on the device. Support from the National Institutes of Health (National Cancer Institute award No. CA137681 and National Institute of Allergy and Infectious Diseases award No. AI100216).

Canada deserves a national health system.

PubMed

Noseworthy, T W

1997-01-01

A defining--some would say peculiar--feature about Canada and Canadians is the strong position that we give social programs within our national identity. FORUM presents an essay by Dr. Thomas Noseworthy based on an address to the annual meeting of the Association of Canadian Medical Colleges in April 1996. In it, Dr. Noseworthy calls for a national health system. He sees the federal government retaining an important role in preserving medicare and, in fact, strengthening its powers in maintaining national consistency and standards. Dr. Noseworthy's views are contrary to the governmental decentralization and devolution of powers occurring across the country. In a "point/counterpoint" exchange on this issue, we have invited commentaries from three experts. Raisa Deber leads off by noting that while a national health system may be desirable, constitutional provisions would be an obstacle. Governments, says Deber, have an inherent conflict of interest between their responsibility for maintaining the health care system and their desire to shift costs. Michael Rachlis reminds us that medicare fulfills important economic as well as social objectives. It helps to support Canada's business competitiveness among other nations. The problem, say Rachlis, is that public financing of health care does not ensure an efficient delivery system. Michael Walker offers some reality orientation. He observes that Canada's health care system is based upon ten public insurance schemes with widely different attributes. While he supports a minimum standard of health care across the country, citizens should be able to purchase private medical insurance and have access to a parallel private health care delivery system. Ultimately, this debate is about who should control social programs: the provinces or the federal government? We'll let you, the readers, decide.

Flexible HVAC System for Lab or Classroom.

ERIC Educational Resources Information Center

Friedan, Jonathan

2001-01-01

Discusses an effort to design a heating, ventilation, and air conditioning system flexible enough to accommodate an easy conversion of classrooms to laboratories and dry labs to wet labs. The design's energy efficiency and operations and maintenance are examined. (GR)

My Green Car: Taking it to the Streets (Ep. 3) – DOE Lab-Corps Video Series

ScienceCinema

Saxena, Samveg; Shah, Nihar; Hansen, Dana

2018-06-12

The researcher team finds enthusiastic consumers at familiar Berkeley hangouts. Then Industry Mentor Russell Carrington pushes the group to consider who will pay for the information the fuel economy app provides. What makes a new technology compelling enough to transition out of the lab and become a consumer product? That’s the question Berkeley Lab researchers Samveg Saxena, Nihar Shah, and Dana Hansen plus industry mentor Russell Carrington set out to answer for MyGreenCar, an app providing personalized fuel economy or electric vehicle range estimates for consumers researching new cars. DOE’s Lab-Corps program offered the technology team some answers. The EERE-funded program, based on the National Science Foundation’s I-Corps™ model for entrepreneurial training, provides tools and training to move energy-related inventions to the marketplace. During Lab-Corp’s intensive six-week session, technology teams interview 100 customer and value chain members to discover which potential products based on their technologies will have significant market pull. A six video series follows the MyGreenCar team’s Lab-Corps experience, from pre-training preparation with the Lab’s Innovation and Partnerships Office through the ups and downs of the customer discovery process. Will the app make it to the marketplace? You’ll just have to watch.

NRL Fact Book 1992-1993

DTIC Science & Technology

1993-06-01

administering contractual support for lab-wide or multiple buys of ADP systems, software, and services. Computer systems located in the Central Computing Facility...Code Dr. D.L. Bradley Vacant Mrs. N.J. Beauchamp Dr. W.A. Kuperman Dr. E.R. Franchi Dr. M.H. Orr Dr. J.A. Bucaro Mr. L.B. Palmer Dr. D.J. Ramsdale Mr

Assessing Usage and Maximizing Finance Lab Impact: A Case Exploration

ERIC Educational Resources Information Center

Noguera, Magdy; Budden, Michael Craig; Silva, Alberto

2011-01-01

This paper reports the results of a survey conducted to assess students' usage and perceptions of a finance lab. Finance labs differ from simple computer labs as they typically contain data boards, streaming market quotes, terminals and software that allow for real-time financial analyses. Despite the fact that such labs represent significant and…

Design of Inquiry-Oriented Science Labs: Impacts on Students' Attitudes

ERIC Educational Resources Information Center

Baseya, J. M.; Francis, C. D.

2011-01-01

Background: Changes in lab style can lead to differences in learning. Two inquiry-oriented lab styles are guided inquiry (GI) and problem-based (PB). Students' attitudes towards lab are important to consider when choosing between GI and PB styles during curriculum design. Purpose: We examined the degree to which lab experiences are explained by a…

Association of HLA-DR1 with the allergic response to the major mugwort pollen allergen: molecular background.

PubMed

Knapp, Bernhard; Fischer, Gottfried; Van Hemelen, Dries; Fae, Ingrid; Maillere, Bernard; Ebner, Christof; Schreiner, Wolfgang; Bohle, Barbara; Jahn-Schmid, Beatrice

2012-08-08

Mugwort pollen allergens represent the main cause of pollinosis in late summer. The major allergen, Art v 1, contains only one single immunodominant, solely HLA-DR-restricted T cell epitope (Art v 125-36). The frequency of HLA-DRB1*01 is highly increased in mugwort-allergic individuals and HLA-DR1 serves as restriction element for Art v 125-36. However, Art v 125-36 also binds to HLA-DR4 with high affinity and DR1-restricted Art v 125-36 -specific T cell receptors can be activated by HLA-DR4 molecules. To understand the predominance of HLA-DR1 in mugwort allergy in spite of the degeneracy in HLA/peptide-binding and TCR-recognition, we investigated the molecular background of Art v 125-36 /MHC/TCR interactions in the context of HLA-DR1 compared to -DR4. The majority of Art v 125-36 -specific T cell lines and clones from HLA-DR1 carrying, mugwort pollen-allergic donors reacted to synthetic and naturally processed Art v 1-peptides when presented by HLA-DR1 or HLA-DR4 expressing antigen presenting cells. However, at limiting peptide concentrations DR1 was more effective in T cell stimulation. In addition, the minimal epitope for 50% of Art v 125-36 -specific T cells was shorter for DR1 than for DR4. In vitro binding assays of Art v 125-36 mutant peptides to isolated DR1- and DR4-molecules indicated similar binding capacities and use of the same register. In silico simulation of Art v 125-36 binding to HLA-DR1 and -DR4 suggested similar binding of the central part of the peptide to either molecule, but a higher flexibility of the N- and C-terminal amino acids and detachment at the C-terminus in HLA-DR1. The predominance of HLA-DR1 in the response to Art v 125-36 may be explained by subtle conformation changes of the peptide bound to DR1 compared to DR4. Computer simulation supported our experimental data by demonstrating differences in peptide mobility within the HLA-DR complex that may influence TCR-binding. We suggest that the minor differences observed in vitro may

The McAndrews Leadership Lecture: February 2015, by Dr Scott Haldeman. Challenges of the Past, Challenges of the Present

PubMed Central

Haldeman, Scott; McAndrews, George P.; Goertz, Christine; Sportelli, Louis; Hamm, Anthony W.; Johnson, Claire

2015-01-01

The McAndrews Leadership Lecture was developed by the American Chiropractic Association to honor the legacy of Jerome F. McAndrews, DC, and George P. McAndrews, JD, and their contributions to the chiropractic profession. This article is a transcription of the presentation made by Dr Scott Haldeman on February 28, 2015, in Washington, DC, at the National Chiropractic Leadership Conference. PMID:26770177

Transforming the advanced lab: Part I - Learning goals

NASA Astrophysics Data System (ADS)

Zwickl, Benjamin; Finkelstein, Noah; Lewandowski, H. J.

2012-02-01

Within the physics education research community relatively little attention has been given to laboratory courses, especially at the upper-division undergraduate level. As part of transforming our senior-level Optics and Modern Physics Lab at the University of Colorado Boulder we are developing learning goals, revising curricula, and creating assessments. In this paper, we report on the establishment of our learning goals and a surrounding framework that have emerged from discussions with a wide variety of faculty, from a review of the literature on labs, and from identifying the goals of existing lab courses. Our goals go beyond those of specific physics content and apparatus, allowing instructors to personalize them to their contexts. We report on four broad themes and associated learning goals: Modeling (math-physics-data connection, statistical error analysis, systematic error, modeling of engineered "black boxes"), Design (of experiments, apparatus, programs, troubleshooting), Communication, and Technical Lab Skills (computer-aided data analysis, LabVIEW, test and measurement equipment).

Student Plagiarism and Faculty Responsibility in Undergraduate Engineering Labs

ERIC Educational Resources Information Center

Parameswaran, Ashvin; Devi, Poornima

2006-01-01

In undergraduate engineering labs, lab reports are routinely copied. By ignoring this form of plagiarism, teaching assistants and lab technicians neglect their role responsibility. By designing courses that facilitate it, however inadvertently, professors neglect their causal responsibility. Using the case of one university, we show via interviews…

Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

NASA Technical Reports Server (NTRS)

1967-01-01

Marshall Space Flight Center (MSFC) Director, Dr. von Braun, is shown leaving the suiting-up van wearing a pressure suit prepared for a tryout in the MSFC Neutral Buoyancy Simulator (NBS). Weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

Celebrating the Life and Legacy of Dr. John Hope Franklin

ERIC Educational Resources Information Center

Harris, Robert L., Jr.; Levering-Lewis, David; French, John D.; Wharton, Clifton R., Jr.

2009-01-01

Dr. John Hope Franklin chronicled the experiences of African-Americans like no one before him, forcing America to recognize Black history as American history. His contributions were innumerable and his impact was abiding. In celebration of his life and legacy, the authors profile the celebrated scholar and activist, Dr. John Hope Franklin.

Ernest Orlando Berkeley National Laboratory - Fundamental and applied research on lean premixed combustion

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Robert K.

Ernest Orland Lawrence Berkeley National Laboratory (Berkeley Lab) is the oldest of America's national laboratories and has been a leader in science and engineering technology for more than 65 years, serving as a powerful resource to meet Us national needs. As a multi-program Department of Energy laboratory, Berkeley Lab is dedicated to performing leading edge research in the biological, physical, materials, chemical, energy, environmental and computing sciences. Ernest Orlando Lawrence, the Lab's founder and the first of its nine Nobel prize winners, invented the cyclotron, which led to a Golden Age of particle physics and revolutionary discoveries about the naturemore » of the universe. To this day, the Lab remains a world center for accelerator and detector innovation and design. The Lab is the birthplace of nuclear medicine and the cradle of invention for medical imaging. In the field of heart disease, Lab researchers were the first to isolate lipoproteins and the first to determine that the ratio of high density to low density lipoproteins is a strong indicator of heart disease risk. The demise of the dinosaurs--the revelation that they had been killed off by a massive comet or asteroid that had slammed into the Earth--was a theory developed here. The invention of the chemical laser, the unlocking of the secrets of photosynthesis--this is a short preview of the legacy of this Laboratory.« less

MTR WING A, TRA604, INTERIOR. BASEMENT. DETAIL OF A19 LAB ...

Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

MTR WING A, TRA-604, INTERIOR. BASEMENT. DETAIL OF A-19 LAB AREA ALONG SOUTH WALL. SIGN ON FLOOR DIRECTS WORKERS TO OBTAIN WHOLE BODY FRISK UPON LEAVING AREA. SIGN ON EQUIPMENT IN CENTER OF VIEW REQUESTS WORKERS TO "NOTIFY HEALTH PHYSICS BEFORE WORKING ON THIS SYSTEM." CAMERA FACING SOUTHWEST. INL NEGATIVE NO. HD46-13-2. Mike Crane, Photographer, 2/2005 - Idaho National Engineering Laboratory, Test Reactor Area, Materials & Engineering Test Reactors, Scoville, Butte County, ID

STS-133 crew during MSS/EVAA TEAM training in Virtual Reality Lab

NASA Image and Video Library

2010-10-01

JSC2010-E-170878 (1 Oct. 2010) --- NASA astronaut Michael Barratt, STS-133 mission specialist, uses the virtual reality lab in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center to train for some of his duties aboard the space shuttle and space station. This type of computer interface, paired with virtual reality training hardware and software, helps to prepare crew members for dealing with space station elements. Photo credit: NASA or National Aeronautics and Space Administration

STS-133 crew during MSS/EVAA TEAM training in Virtual Reality Lab

NASA Image and Video Library

2010-10-01

JSC2010-E-170888 (1 Oct. 2010) --- NASA astronaut Nicole Stott, STS-133 mission specialist, uses the virtual reality lab in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center to train for some of her duties aboard the space shuttle and space station. This type of computer interface, paired with virtual reality training hardware and software, helps to prepare crew members for dealing with space station elements. Photo credit: NASA or National Aeronautics and Space Administration

STS-133 crew during MSS/EVAA TEAM training in Virtual Reality Lab

NASA Image and Video Library

2010-10-01

JSC2010-E-170882 (1 Oct. 2010) --- NASA astronaut Nicole Stott, STS-133 mission specialist, uses the virtual reality lab in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center to train for some of her duties aboard the space shuttle and space station. This type of computer interface, paired with virtual reality training hardware and software, helps to prepare crew members for dealing with space station elements. Photo credit: NASA or National Aeronautics and Space Administration

The watershed years of 1958-1962 in the Harvard Pigeon Lab.

PubMed Central

Catania, A Charles

2002-01-01

During the years 1958-1962, the final years of support by the National Science Foundation for B. F. Skinner's Pigeon Lab in Memorial Hall at Harvard University, 20 or so pigeon experiments (plus some with other organisms) ran concurrently 7 days a week. The research style emphasized experimental analyses, exploratory procedures, and the parametric exploration of variables. This reminiscence describes some features of the laboratory, the context within which it operated, and the activities of some of those who participated in it. PMID:12083685

DR2 blocker thioridazine: A promising drug for ovarian cancer therapy

PubMed Central

Yong, Min; Yu, Tinghe; Tian, Si; Liu, Shuaibin; Xu, Jiao; Hu, Jianguo; Hu, Lina

2017-01-01

Dopamine receptor 2 (DR2) may be a biomarker for various types of cancer. Ovarian cancer cells overexpress DR2; therefore, blocking DR2 may be a novel treatment strategy for ovarian cancer. Thioridazine, a DR2 blocker, has antineoplastic activity in a variety of cancer cells. In view of the requirement for novel therapeutic agents in ovarian cancer, the present study aimed to determine the potential effects of thioridazine in vitro and in vivo. It was revealed that the DR2 blocker thioridazine induced cell death in a dose-dependent manner in ovarian cancer cells. Thioridazine treatment induced apoptosis and autophagy, which may be attributed to an increased level of reactive oxygen species and associated DNA damage. Additionally, the expression of various proteins increased with oxidative stress, including nuclear factor E2-related factor 2, which is a pivotal transcriptional factor involved in cellular responses to oxidative stress. Heme oxygenase 1, NAPDH quinone dehydrogenase 1 and hypoxia inducible factor-1α and phosphorylated (p)-protein kinase B expression was significantly decreased, and the expression level of p-extracellular signal-related kinases and p-P38 was increased. Using 3-methyl adenine to inhibit autophagy caused the rate of apoptosis to increase. Thioridazine inhibited the growth of SKOV3 xenografts in nude mice. The present study demonstrated that the DR2 blocker thioridazine exhibited anticancer effects in vitro and in vivo, suggesting that thioridazine may be used as a potential drug in ovarian cancer therapy. PMID:29344260

Using lab notebooks to examine students' engagement in modeling in an upper-division electronics lab course

NASA Astrophysics Data System (ADS)

Stanley, Jacob T.; Su, Weifeng; Lewandowski, H. J.

2017-12-01

We demonstrate how students' use of modeling can be examined and assessed using student notebooks collected from an upper-division electronics lab course. The use of models is a ubiquitous practice in undergraduate physics education, but the process of constructing, testing, and refining these models is much less common. We focus our attention on a lab course that has been transformed to engage students in this modeling process during lab activities. The design of the lab activities was guided by a framework that captures the different components of model-based reasoning, called the Modeling Framework for Experimental Physics. We demonstrate how this framework can be used to assess students' written work and to identify how students' model-based reasoning differed from activity to activity. Broadly speaking, we were able to identify the different steps of students' model-based reasoning and assess the completeness of their reasoning. Varying degrees of scaffolding present across the activities had an impact on how thoroughly students would engage in the full modeling process, with more scaffolded activities resulting in more thorough engagement with the process. Finally, we identified that the step in the process with which students had the most difficulty was the comparison between their interpreted data and their model prediction. Students did not use sufficiently sophisticated criteria in evaluating such comparisons, which had the effect of halting the modeling process. This may indicate that in order to engage students further in using model-based reasoning during lab activities, the instructor needs to provide further scaffolding for how students make these types of experimental comparisons. This is an important design consideration for other such courses attempting to incorporate modeling as a learning goal.

Dr. Robert Goddard

NASA Image and Video Library

2010-01-04

1930—Preparations are made to unreal remote control wires. The shelter in distance is 1,000 feet from Dr. Robert Goddard’s rocket launching tower, 10 miles northwest of Roswell, New Mexico. The shelter at left is 55 feet from the tower, and was used for static test only. It was later removed. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Join us on Facebook

[Instituto de Investigaciones Clinicas "Dr. Américo Negrette": 55 years of excellent research versus global economic recession].

PubMed

Valero Cedeño, Nereida Josefina

2014-12-01

The Instituto de Investigaciones Clínicas "Dr. Américo Negrette" belongs to the Faculty of Medicine at University of Zulia in Maracaibo, Zulia State, Venezuela. It was created on December 4, 1959 by Dr. Américo Negrette. Today, with 55 years of existence, the Institute seeks to fulfill the mission that characterizes it, based on the values instilled by its founder and maintained by subsequent generations, whose research projects are implemented through seven research sections: Biochemistry, Hematologic Research, Neuropharmacology and Neuroscience, Immunology and Cell Biology, Clinical Neurochemistry, Parasitology and Virology. The research originated in these laboratories have become national and international points of reference, despite the current economic situation with budget deficits that put at risk the quality and originality of their projects with negative consequences on the productivity and applications for health population, reasons of biomedical research.

DR5 as a reporter system to study auxin response in Populus.

PubMed

Chen, Yiru; Yordanov, Yordan S; Ma, Cathleen; Strauss, Steven; Busov, Victor B

2013-03-01

KEY MESSAGE : Auxin responsive promoter DR5 reporter system is functional in Populus to monitor auxin response in tissues including leaves, roots, and stems. We described the behavior of the DR5::GUS reporter system in stably transformed Populus plants. We found several similarities with Arabidopsis, including sensitivity to native and synthetic auxins, rapid induction after treatment in a variety of tissues, and maximal responses in root tissues. There were also several important differences from Arabidopsis, including slower time to maximum response and lower induction amplitude. Young leaves and stem sections below the apex showed much higher DR5 activity than did older leaves and stems undergoing secondary growth. DR5 activity was highest in cortex, suggesting high levels of auxin concentration and/or sensitivity in this tissue. Our study shows that the DR5 reporter system is a sensitive and facile system for monitoring auxin responses and distribution at cellular resolution in poplar.

DNA Microarray Wet Lab Simulation Brings Genomics into the High School Curriculum

PubMed Central

Zanta, Carolyn A.; Heyer, Laurie J.; Kittinger, Ben; Gabric, Kathleen M.; Adler, Leslie

2006-01-01

We have developed a wet lab DNA microarray simulation as part of a complete DNA microarray module for high school students. The wet lab simulation has been field tested with high school students in Illinois and Maryland as well as in workshops with high school teachers from across the nation. Instead of using DNA, our simulation is based on pH indicators, which offer many ideal teaching characteristics. The simulation requires no specialized equipment, is very inexpensive, is very reliable, and takes very little preparation time. Student and teacher assessment data indicate the simulation is popular with both groups, and students show significant learning gains. We include many resources with this publication, including all prelab introductory materials (e.g., a paper microarray activity), the student handouts, teachers notes, and pre- and postassessment tools. We did not test the simulation on other student populations, but based on teacher feedback, the simulation also may fit well in community college and in introductory and nonmajors' college biology curricula. PMID:17146040

DNA microarray wet lab simulation brings genomics into the high school curriculum.

PubMed

Campbell, A Malcolm; Zanta, Carolyn A; Heyer, Laurie J; Kittinger, Ben; Gabric, Kathleen M; Adler, Leslie; Schulz, Barbara

2006-01-01

We have developed a wet lab DNA microarray simulation as part of a complete DNA microarray module for high school students. The wet lab simulation has been field tested with high school students in Illinois and Maryland as well as in workshops with high school teachers from across the nation. Instead of using DNA, our simulation is based on pH indicators, which offer many ideal teaching characteristics. The simulation requires no specialized equipment, is very inexpensive, is very reliable, and takes very little preparation time. Student and teacher assessment data indicate the simulation is popular with both groups, and students show significant learning gains. We include many resources with this publication, including all prelab introductory materials (e.g., a paper microarray activity), the student handouts, teachers notes, and pre- and postassessment tools. We did not test the simulation on other student populations, but based on teacher feedback, the simulation also may fit well in community college and in introductory and nonmajors' college biology curricula.

ORAC-DR: One Pipeline for Multiple Telescopes

NASA Astrophysics Data System (ADS)

Cavanagh, B.; Hirst, P.; Jenness, T.; Economou, F.; Currie, M. J.; Todd, S.; Ryder, S. D.

ORAC-DR, a flexible and extensible data reduction pipeline, has been successfully used for real-time data reduction from UFTI and IRCAM (infrared cameras), CGS4 (near-infrared spectrometer), Michelle (mid-infrared imager and echelle spectrometer), at UKIRT; and SCUBA (sub-millimeter bolometer array) at JCMT. We have now added the infrared imaging spectrometers IRIS2 at the Anglo-Australian Telescope and UIST at UKIRT to the list of officially supported instruments. We also present initial integral field unit support for UIST, along with unofficial support for the imager and multi-object spectrograph GMOS at Gemini. This paper briefly describes features of the pipeline along with details of adopting ORAC-DR for other instruments on telescopes around the world.

What We Do | Frederick National Laboratory for Cancer Research

Cancer.gov

The Frederick National Laboratory is the only U.S. national lab wholly focused on research, technology, and collaboration in the biomedical sciences- working to discover, to innovate, and to improve human health. We accelerate progress against can

Dr. Ray Gause examines student Skylab experiment ED-52 Web Formation

NASA Technical Reports Server (NTRS)

1973-01-01

Dr. Ray Gause of the NASA-Marshall Space Flight Center (MSFC) places dinner, in the form of a housefly, in the web of Arabella - the prime spider for the ED-52 Web Formation Experiment. Arabella can be delineated near the end of the black pen in Dr. Gause's hand. The experiment is one of 25 student experiments accepted for the Skylab program and will be performed during the Skylab 3 mission. Judy Miles, a 17-year-old high school student from Lexington, Massachusetts, is the student experimenter and Dr. Gause is the NASA student advisor.

Effectiveness of a Lab Manual Delivered on CD-ROM

ERIC Educational Resources Information Center

Brickman, Peggy; Ketter, Catherine A. Teare; Pereira, Monica

2005-01-01

Although electronic instructional media are becoming increasingly prevalent in science classrooms, their worth remains unproven. Here, student perceptions and performance using CD-ROM delivery of lab materials are assessed. Numerous learning barriers that produced lower lab grades for students using a CD-ROM lab manual in comparison to a print…

Gaia DR1 documentation Chapter 6: Variability

NASA Astrophysics Data System (ADS)

Eyer, L.; Rimoldini, L.; Guy, L.; Holl, B.; Clementini, G.; Cuypers, J.; Mowlavi, N.; Lecoeur-Taïbi, I.; De Ridder, J.; Charnas, J.; Nienartowicz, K.

2017-12-01

This chapter describes the photometric variability processing of the Gaia DR1 data. Coordination Unit 7 is responsible for the variability analysis of over a billion celestial sources. In particular the definition, design, development, validation and provision of a software package for the data processing of photometrically variable objects. Data Processing Centre Geneva (DPCG) responsibilities cover all issues related to the computational part of the CU7 analysis. These span: hardware provisioning, including selection, deployment and optimisation of suitable hardware, choosing and developing software architecture, defining data and scientific workflows as well as operational activities such as configuration management, data import, time series reconstruction, storage and processing handling, visualisation and data export. CU7/DPCG is also responsible for interaction with other DPCs and CUs, software and programming training for the CU7 members, scientific software quality control and management of software and data lifecycle. Details about the specific data treatment steps of the Gaia DR1 data products are found in Eyer et al. (2017) and are not repeated here. The variability content of the Gaia DR1 focusses on a subsample of Cepheids and RR Lyrae stars around the South ecliptic pole, showcasing the performance of the Gaia photometry with respect to variable objects.

77 FR 59888 - General Conference Committee of the National Poultry Improvement Plan

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-01

... Inspection Service [Docket No. APHIS-2012-0068] General Conference Committee of the National Poultry... the General Conference Committee of the National Poultry Improvement Plan (Committee) for a 2year... interest. FOR FURTHER INFORMATION CONTACT: Dr. C. Stephen Roney, Senior Coordinator, National Poultry...

California State University, Northridge: Hybrid Lab Courses

ERIC Educational Resources Information Center

EDUCAUSE, 2014

2014-01-01

California State University, Northridge's Hybrid Lab course model targets high failure rate, multisection, gateway courses in which prerequisite knowledge is a key to success. The Hybrid Lab course model components incorporate interventions and practices that have proven successful at CSUN and other campuses in supporting students, particularly…

The Portable Usability Testing Lab: A Flexible Research Tool.

ERIC Educational Resources Information Center

Hale, Michael E.; And Others

A group of faculty at the University of Georgia obtained funding for a research and development facility called the Learning and Performance Support Laboratory (LPSL). One of the LPSL's primary needs was obtaining a portable usability lab for software testing, so the facility obtained the "Luggage Lab 2000." The lab is transportable to…

Modifying Cookbook Labs.

ERIC Educational Resources Information Center

Clark, Robert, L.; Clough, Michael P.; Berg, Craig A.

2000-01-01

Modifies an extended lab activity from a cookbook approach for determining the percent mass of water in copper sulfate pentahydrate crystals to one which incorporates students' prior knowledge, engenders active mental struggling with prior knowledge and new experiences, and encourages metacognition. (Contains 12 references.) (ASK)

Congress split on best way to reshape network of labs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawler, A.

Reducing the size of the federal bureaucracy was a bread-and -butter issue for the Republicans who took over Congress in January. And the Department of Energy`s (DOE`s) $6 billion network of national laboratories seemed like a tempting morsel. But 9 months later, congressional plates are loaded down with competing plans to reform the DOE labs, and the issue is giving majority members a case of indigestion. Their discomfort seems likely to delay adoption of any reform plans until at least next year. This article discusses the broad alternatives and possibilities for the future.

Antennas and Electromagnetics Instrumentation for Research and Education

DTIC Science & Technology

2016-06-01

Antennas and Electromagnetics Instrumentation for Research and Education The objective of this proposal is to enhance the instrumentation of FIU’s... ElectroMagnetics Lab (EMLab) directed by Dr. Georgakopoulos and create a state-of-the art lab that will support the following: (a) Dr. Georgakopoulos...funded research on reconfigurable antennas and wireless power transfer, (b) other research on advanced electromagnetic technologies that support

D&R Siding Co., LLC Information Sheet

EPA Pesticide Factsheets

D&R Siding Co., LLC (the Company) is located in Shelbyville, Tennessee. The settlement involves renovation activities conducted at a property constructed prior to 1978, located in Fayetteville, Tennessee.

Thinking Outside the Lab

NASA Astrophysics Data System (ADS)

Colter, Tabitha

2017-01-01

As an undergraduate physics major who spent 2015 deep in a quantum optics lab at Oak Ridge National Laboratory, I knew my 2016 experience with the House of Representatives Energy and Commerce Committee would be a completely new challenge. I have long had a passion for the bridge of communication between the technical and non-technical worlds but it was only through my AIP Mather internship this summer that I was able to see that passion come to life in the realm of science policy. Suddenly, I went from squeezing political philosophy classes into my packed schedule to witnessing the political process first-hand. I was thrilled to find that the skills of critical thinking and communicating complex issues I have developed throughout my training as a physicist were directly applicable to my work in Congress. Overall, my experience this summer has given me insight into the inner workings of the federal policy process, deepened my appreciation for the work of government employees to keep Congressional members informed on the pressing current issues, and exposed me to a whole range of alternative careers within science. AIP and SPS

ASM LabCap's contributions to disease surveillance and the International Health Regulations (2005).

PubMed

Specter, Steven; Schuermann, Lily; Hakiruwizera, Celestin; Sow, Mah-Séré Keita

2010-12-03

The revised International Health Regulations [IHR(2005)], which requires the Member States of the World Health Organization (WHO) to develop core capacities to detect, assess, report, and respond to public health threats, is bringing new challenges for national and international surveillance systems. As more countries move toward implementation and/or strengthening of their infectious disease surveillance programs, the strengthening of clinical microbiology laboratories becomes increasingly important because they serve as the first line responders to detect new and emerging microbial threats, re-emerging infectious diseases, the spread of antibiotic resistance, and the possibility of bioterrorism. In fact, IHR(2005) Core Capacity #8, "Laboratory", requires that laboratory services be a part of every phase of alert and response.Public health laboratories in many resource-constrained countries require financial and technical assistance to build their capacity. In recognition of this, in 2006, the American Society for Microbiology (ASM) established an International Laboratory Capacity Building Program, LabCap, housed under the ASM International Board. ASM LabCap utilizes ASM's vast resources and its membership's expertise-40,000 microbiologists worldwide-to strengthen clinical and public health laboratory systems in low and low-middle income countries. ASM LabCap's program activities align with HR(2005) by building the capability of resource-constrained countries to develop quality-assured, laboratory-based information which is critical to disease surveillance and the rapid detection of disease outbreaks, whether they stem from natural, deliberate or accidental causes.ASM LabCap helps build laboratory capacity under a cooperative agreement with the U.S. Centers for Disease Control and Prevention (CDC) and under a sub-contract with the Program for Appropriate Technology in Health (PATH) funded by the United States Agency for International Development (USAID

77 FR 76297 - National Institute of Dental & Craniofacial Research; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-27

... DEPARTMENT OF HEALTH AND HUMAN SERVICES National Institutes of Health National Institute of Dental..., Bethesda, MD 20892, 301-594-0652, [email protected] . Name of Committee: National Institute of Dental... of Dental & Craniofacial Research, National Institutes of Health, 45 Center Dr. Room 4AN 32J...

Randomly auditing research labs could be an affordable way to improve research quality: A simulation study

PubMed Central

Zardo, Pauline; Graves, Nicholas

2018-01-01

The “publish or perish” incentive drives many researchers to increase the quantity of their papers at the cost of quality. Lowering quality increases the number of false positive errors which is a key cause of the reproducibility crisis. We adapted a previously published simulation of the research world where labs that produce many papers are more likely to have “child” labs that inherit their characteristics. This selection creates a competitive spiral that favours quantity over quality. To try to halt the competitive spiral we added random audits that could detect and remove labs with a high proportion of false positives, and also improved the behaviour of “child” and “parent” labs who increased their effort and so lowered their probability of making a false positive error. Without auditing, only 0.2% of simulations did not experience the competitive spiral, defined by a convergence to the highest possible false positive probability. Auditing 1.35% of papers avoided the competitive spiral in 71% of simulations, and auditing 1.94% of papers in 95% of simulations. Audits worked best when they were only applied to established labs with 50 or more papers compared with labs with 25 or more papers. Adding a ±20% random error to the number of false positives to simulate peer reviewer error did not reduce the audits’ efficacy. The main benefit of the audits was via the increase in effort in “child” and “parent” labs. Audits improved the literature by reducing the number of false positives from 30.2 per 100 papers to 12.3 per 100 papers. Auditing 1.94% of papers would cost an estimated $15.9 million per year if applied to papers produced by National Institutes of Health funding. Our simulation greatly simplifies the research world and there are many unanswered questions about if and how audits would work that can only be addressed by a trial of an audit. PMID:29649314

Randomly auditing research labs could be an affordable way to improve research quality: A simulation study.

PubMed

Barnett, Adrian G; Zardo, Pauline; Graves, Nicholas

2018-01-01

The "publish or perish" incentive drives many researchers to increase the quantity of their papers at the cost of quality. Lowering quality increases the number of false positive errors which is a key cause of the reproducibility crisis. We adapted a previously published simulation of the research world where labs that produce many papers are more likely to have "child" labs that inherit their characteristics. This selection creates a competitive spiral that favours quantity over quality. To try to halt the competitive spiral we added random audits that could detect and remove labs with a high proportion of false positives, and also improved the behaviour of "child" and "parent" labs who increased their effort and so lowered their probability of making a false positive error. Without auditing, only 0.2% of simulations did not experience the competitive spiral, defined by a convergence to the highest possible false positive probability. Auditing 1.35% of papers avoided the competitive spiral in 71% of simulations, and auditing 1.94% of papers in 95% of simulations. Audits worked best when they were only applied to established labs with 50 or more papers compared with labs with 25 or more papers. Adding a ±20% random error to the number of false positives to simulate peer reviewer error did not reduce the audits' efficacy. The main benefit of the audits was via the increase in effort in "child" and "parent" labs. Audits improved the literature by reducing the number of false positives from 30.2 per 100 papers to 12.3 per 100 papers. Auditing 1.94% of papers would cost an estimated $15.9 million per year if applied to papers produced by National Institutes of Health funding. Our simulation greatly simplifies the research world and there are many unanswered questions about if and how audits would work that can only be addressed by a trial of an audit.

Traditional Labs + New Questions = Improved Student Performance.

ERIC Educational Resources Information Center

Rezba, Richard J.; And Others

1992-01-01

Presents three typical lab activities involving the breathing rate of fish, the behavior of electromagnets, and tests for water hardness to demonstrate how labs can be modified to teach process skills. Discusses how basic concepts about experimentation are developed and ways of generating and improving science experiments. Includes a laboratory…

The Advanced Labs Website: resources for upper-level laboratories

NASA Astrophysics Data System (ADS)

Torres-Isea, Ramon

2012-03-01

The Advanced Labs web resource collection is an effort to create a central, comprehensive information base for college/university faculty who teach upper-level undergraduate laboratories. The website is produced by the American Association of Physics Teachers (AAPT). It is a part of ComPADRE, the online collection of resources in physics and astronomy education, which itself is a part of the National Science Foundation-funded National Science Digital Library (NSDL). After a brief review of its history, we will discuss the current status of the website while describing the various types of resources available at the site and presenting examples of each. We will detail a step-by-step procedure for submitting resources to the website. The resource collection is designed to be a community effort and thus welcomes input and contributions from its users. We will also present plans, and will seek audience feedback, for additional website services and features. The constraints, roadblocks, and rewards of this project will also be addressed.

[Notes on the Indian Red Crescent aid and Dr. Ensari's contributions before the decline of the Ottoman Empire].

PubMed

Izgöer, Ahmet Zeki

2002-01-01

This article deals with the Indian Red Crescent aids and Dr. Ahmed Ensari's role in this activity during the wars in the early 20th century that led the Ottoman Empire to dismantle. The Indian Red Crescent presided by Dr. Ensari sent a medical team and sanitary material for the Ottomans battered during the war in Tripoli (1911) and the succeeding war at the Balkans (1912). The article also deals with the meetings of the above-mentioned medical team with the Ottoman statesmen and dignitaries; its success at the Tripoli front and its projects concerning the Ottoman immigrants from the Balkan region. The humanitarian aids of the Indian Red Crescent continued afterwards, especially during the World War II (1914-1918) and the War of Independence (1919-1922). On their return to India, Dr. Ensari and the members of the team held a series of meetings and spoke of their activities to the people in their country. They tried to spread their sympathy for the Ottoman-Turkish people even to the outposts of India. This article is an attempt to describe the sympathy of this brother nation (Pakistan of today) proved by their aids and support far away from their borders.

Low Temperature Pulsed Plasma Deposition. Part 1. A New Technique for Thin Film Deposition with Complete Gas Dissociation.

DTIC Science & Technology

1988-04-12

Res. Minneapolis Dr P Klocek Texas Instruments, Dallas Dr D N Lewis Naval Research Lab Dr S Musikant General Electric Co, Philadelphia Dr D Perry US...by utilising only a small fraction of the available reactants. Not only is this wasteful, limiting the method to reactants that are comparatively

Dr. von Braun Tries Out the Neutral Buoyancy Simulator (NBS)

NASA Technical Reports Server (NTRS)

1967-01-01

Astronaut L. Gordon Cooper checks the neck ring of a space suit worn by Marshall Space Flight Center (MSFC) Director, Dr. von Braun before he submerges into the water of the MSFC Neutral Buoyancy Simulator (NBS). Wearing a pressurized suit and weighted to a neutrally buoyant condition, Dr. von Braun was able to perform tasks underwater which simulated weightless conditions found in space.

DR2DI: a powerful computational tool for predicting novel drug-disease associations

NASA Astrophysics Data System (ADS)

Lu, Lu; Yu, Hua

2018-05-01

Finding the new related candidate diseases for known drugs provides an effective method for fast-speed and low-risk drug development. However, experimental identification of drug-disease associations is expensive and time-consuming. This motivates the need for developing in silico computational methods that can infer true drug-disease pairs with high confidence. In this study, we presented a novel and powerful computational tool, DR2DI, for accurately uncovering the potential associations between drugs and diseases using high-dimensional and heterogeneous omics data as information sources. Based on a unified and extended similarity kernel framework, DR2DI inferred the unknown relationships between drugs and diseases using Regularized Kernel Classifier. Importantly, DR2DI employed a semi-supervised and global learning algorithm which can be applied to uncover the diseases (drugs) associated with known and novel drugs (diseases). In silico global validation experiments showed that DR2DI significantly outperforms recent two approaches for predicting drug-disease associations. Detailed case studies further demonstrated that the therapeutic indications and side effects of drugs predicted by DR2DI could be validated by existing database records and literature, suggesting that DR2DI can be served as a useful bioinformatic tool for identifying the potential drug-disease associations and guiding drug repositioning. Our software and comparison codes are freely available at https://github.com/huayu1111/DR2DI.

DR2DI: a powerful computational tool for predicting novel drug-disease associations

NASA Astrophysics Data System (ADS)

Lu, Lu; Yu, Hua

2018-04-01

Finding the new related candidate diseases for known drugs provides an effective method for fast-speed and low-risk drug development. However, experimental identification of drug-disease associations is expensive and time-consuming. This motivates the need for developing in silico computational methods that can infer true drug-disease pairs with high confidence. In this study, we presented a novel and powerful computational tool, DR2DI, for accurately uncovering the potential associations between drugs and diseases using high-dimensional and heterogeneous omics data as information sources. Based on a unified and extended similarity kernel framework, DR2DI inferred the unknown relationships between drugs and diseases using Regularized Kernel Classifier. Importantly, DR2DI employed a semi-supervised and global learning algorithm which can be applied to uncover the diseases (drugs) associated with known and novel drugs (diseases). In silico global validation experiments showed that DR2DI significantly outperforms recent two approaches for predicting drug-disease associations. Detailed case studies further demonstrated that the therapeutic indications and side effects of drugs predicted by DR2DI could be validated by existing database records and literature, suggesting that DR2DI can be served as a useful bioinformatic tool for identifying the potential drug-disease associations and guiding drug repositioning. Our software and comparison codes are freely available at https://github.com/huayu1111/DR2DI.

Validation study of the in vitro skin irritation test with the LabCyte EPI-MODEL24.

PubMed

Kojima, Hajime; Ando, Yoko; Idehara, Kenji; Katoh, Masakazu; Kosaka, Tadashi; Miyaoka, Etsuyoshi; Shinoda, Shinsuke; Suzuki, Tamie; Yamaguchi, Yoshihiro; Yoshimura, Isao; Yuasa, Atsuko; Watanabe, Yukihiko; Omori, Takashi

2012-03-01

A validation study on an in vitro skin irritation assay was performed with the reconstructed human epidermis (RhE) LabCyte EPI-MODEL24, developed by Japan Tissue Engineering Co. Ltd (Gamagori, Japan). The protocol that was followed in the current study was an optimised version of the EpiSkin protocol (LabCyte assay). According to the United Nations Globally Harmonised System (UN GHS) of classification for assessing the skin irritation potential of a chemical, 12 irritants and 13 non-irritants were validated by a minimum of six laboratories from the Japanese Society for Alternatives to Animal Experiments (JSAAE) skin irritation assay validation study management team (VMT). The 25 chemicals were listed in the European Centre for the Validation of Alternative Methods (ECVAM) performance standards. The reconstructed tissues were exposed to the chemicals for 15 minutes and incubated for 42 hours in fresh culture medium. Subsequently, the level of interleukin-1 alpha (IL-1 α) present in the conditioned medium was measured, and tissue viability was assessed by using the MTT assay. The results of the MTT assay obtained with the LabCyte EPI-MODEL24 (LabCyte MTT assay) demonstrated high within-laboratory and between-laboratory reproducibility, as well as high accuracy for use as a stand-alone assay to distinguish skin irritants from non-irritants. In addition, the IL-1α release measurements in the LabCyte assay were clearly unnecessary for the success of this model in the classification of chemicals for skin irritation potential. 2012 FRAME.

A Well-Maintained Lab Is a Safer Lab. Safety Spotlight

ERIC Educational Resources Information Center

Walls, William H.; Strimel, Greg J.

2018-01-01

Administration and funding can cause Engineering/Technology Education (ETE) programs to thrive or die. To administrators, the production/prototyping equipment and laboratory setting are often viewed as the features that set ETE apart from other school subjects. A lab is a unique gift as well as a responsibility. If an administrator can see that…

Candidate members of the Pal 5, GD-1, Cetus Polar and Orphan tidal stellar halo streams from SDSS DR9, LAMOST DR3 and APOGEE catalogs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Li, Guang -Wei; Yanny, Brian; Zhang, Hao -Tong

We present candidate members of the Pal 5, GD-1, Cetus Polar, and Orphan tidal stellar streams found in LAMOST DR3, SDSS DR9 and APOGEE catalogs. In LAMOST DR3, we find 20, 4, 24 high confidence candidates of tidal streams GD-1, Cetus Polar and Orphan respectively. We also list from the SDSS DR9 spectroscopic catalog 59, 118, 10 high confidence candidates of tidal streams Cetus Polar, Orphan and Pal 5, respectively. Furthermore, we find 7 high confidence candidates of the Pal 5 tidal stream in APOGEE data. Compared with SDSS, the new candidates from LAMOST DR3 are brighter, so that together, more of the color-magnitude diagram, including the giant branch can be explored. Analysis of SDSS data shows that there are 3 metallicity peaks of the Orphan stream and also shows some spatial separation. LAMOST data confirms multiple metallicities in this stream. The metallicity, given by the higher resolution APOGEE instrument, of the Pal 5 tidal stream is [Fe/H]more » $$\\sim -1.2$$, higher than that given earlier by SDSS spectra. Here, many previously unidentified stream members are tabulated here for the first time, along with existing members, allowing future researchers to further constrain the orbits of these objects as they move within the Galaxy's dark matter potential.« less

Candidate members of the Pal 5, GD-1, Cetus Polar and Orphan tidal stellar halo streams from SDSS DR9, LAMOST DR3 and APOGEE catalogs

DOE PAGES

Li, Guang -Wei; Yanny, Brian; Zhang, Hao -Tong; ...

2017-05-01

We present candidate members of the Pal 5, GD-1, Cetus Polar, and Orphan tidal stellar streams found in LAMOST DR3, SDSS DR9 and APOGEE catalogs. In LAMOST DR3, we find 20, 4, 24 high confidence candidates of tidal streams GD-1, Cetus Polar and Orphan respectively. We also list from the SDSS DR9 spectroscopic catalog 59, 118, 10 high confidence candidates of tidal streams Cetus Polar, Orphan and Pal 5, respectively. Furthermore, we find 7 high confidence candidates of the Pal 5 tidal stream in APOGEE data. Compared with SDSS, the new candidates from LAMOST DR3 are brighter, so that together, more of the color-magnitude diagram, including the giant branch can be explored. Analysis of SDSS data shows that there are 3 metallicity peaks of the Orphan stream and also shows some spatial separation. LAMOST data confirms multiple metallicities in this stream. The metallicity, given by the higher resolution APOGEE instrument, of the Pal 5 tidal stream is [Fe/H]more » $$\\sim -1.2$$, higher than that given earlier by SDSS spectra. Here, many previously unidentified stream members are tabulated here for the first time, along with existing members, allowing future researchers to further constrain the orbits of these objects as they move within the Galaxy's dark matter potential.« less

MatLab Programming for Engineers Having No Formal Programming Knowledge

NASA Technical Reports Server (NTRS)

Shaykhian, Linda H.; Shaykhian, Gholam Ali

2007-01-01

MatLab is one of the most widely used very high level programming languages for Scientific and engineering computations. It is very user-friendly and needs practically no formal programming knowledge. Presented here are MatLab programming aspects and not just the MatLab commands for scientists and engineers who do not have formal programming training and also have no significant time to spare for learning programming to solve their real world problems. Specifically provided are programs for visualization. Also, stated are the current limitations of the MatLab, which possibly can be taken care of by Mathworks Inc. in a future version to make MatLab more versatile.

eComLab: remote laboratory platform

NASA Astrophysics Data System (ADS)

Pontual, Murillo; Melkonyan, Arsen; Gampe, Andreas; Huang, Grant; Akopian, David

2011-06-01

Hands-on experiments with electronic devices have been recognized as an important element in the field of engineering to help students get familiar with theoretical concepts and practical tasks. The continuing increase the student number, costly laboratory equipment, and laboratory maintenance slow down the physical lab efficiency. As information technology continues to evolve, the Internet has become a common media in modern education. Internetbased remote laboratory can solve a lot of restrictions, providing hands-on training as they can be flexible in time and the same equipment can be shared between different students. This article describes an on-going remote hands-on experimental radio modulation, network and mobile applications lab project "eComLab". Its main component is a remote laboratory infrastructure and server management system featuring various online media familiar with modern students, such as chat rooms and video streaming.

Engaging Families in Partnership Programs to Promote Student Success: Q&A for Dr. Joyce L. Epstein. REL Mid-Atlantic Educator Effectiveness Webinar Series

ERIC Educational Resources Information Center

Regional Educational Laboratory Mid-Atlantic, 2015

2015-01-01

In this webinar, Dr. Joyce Epstein, Director of the Center on School, Family, and Community Partnerships and the National Network of Partnership Schools, discussed what the research says about effective family engagement. The webinar and PowerPoint presentation are also available. A brief list of resources is included.

The McAndrews Leadership Lecture: February 2016, by Dr Greg Kawchuk. Putting the "Act" Back in Chiropractic.

PubMed

Kawchuk, Gregory Neil

2017-12-01

The McAndrews Leadership Lecture was developed by the American Chiropractic Association to honor the legacy of Jerome F. McAndrews, DC, and George P. McAndrews, JD, and their contributions to the chiropractic profession. This article is an edited and truncated version of the McAndrews Leadership Lecture given by Dr Greg Kawchuk on February 27, 2016, in Washington, DC, at the National Chiropractic Leadership Conference. This was the second McAndrews lecture in this annual series.

GENESI-DR - A single access point to Earth Science data

NASA Astrophysics Data System (ADS)

Cossu, R.; Goncalves, P.; Pacini, F.

2009-04-01

The amount of information being generated about our planet is increasing at an exponential rate, but it must be easily accessible in order to apply it to the global needs relating to the state of the Earth. Currently, information about the state of the Earth, relevant services, analysis results, applications and tools are accessible in a very scattered and uncoordinated way, often through individual initiatives from Earth Observation mission operators, scientific institutes dealing with ground measurements, service companies, data catalogues, etc. A dedicated infrastructure providing transparent access to all this will support Earth Science communities by allowing them to easily and quickly derive objective information and share knowledge based on all environmentally sensitive domains. The use of high-speed networks (GÉANT) and the experimentation of new technologies, like BitTorrent, will also contribute to better services for the Earth Science communities. GENESI-DR (Ground European Network for Earth Science Interoperations - Digital Repositories), an ESA-led, European Commission (EC)-funded two-year project, is taking the lead in providing reliable, easy, long-term access to Earth Science data via the Internet. This project will allow scientists from different Earth Science disciplines located across Europe to locate, access, combine and integrate historical and fresh Earth-related data from space, airborne and in-situ sensors archived in large distributed repositories. GENESI-DR builds a federated collection of heterogeneous digital Earth Science repositories to establish a dedicated infrastructure providing transparent access to all this and allowing Earth Science communities to easily and quickly derive objective information and share knowledge based on all environmentally sensitive domains. The federated digital repositories, seen as services and data providers, will share access to their resources (catalogue functions, data access, processing services etc

Field Evaluation of Highly Insulating Windows in the Lab Homes: Winter Experiment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Parker, Graham B.; Widder, Sarah H.; Bauman, Nathan N.

2012-06-01

This field evaluation of highly insulating windows was undertaken in a matched pair of 'Lab Homes' located on the Pacific Northwest National Laboratory (PNNL) campus during the 2012 winter heating season. Improving the insulation and solar heat gain characteristics of a home's windows has the potential to significantly improve the home's building envelope and overall thermal performance by reducing heat loss (in the winter), and cooling loss and solar heat gain (in the summer) through the windows. A high quality installation and/or window retrofit will also minimize or reduce air leakage through the window cavity and thus also contribute tomore » reduced heat loss in the winter and cooling loss in the summer. These improvements all contribute to decreasing overall annual home energy use. Occupant comfort (non-quantifiable) can also be increased by minimizing or eliminating the cold 'draft' (temperature) many residents experience at or near window surfaces that are at a noticeably lower temperature than the room air temperature. Lastly, although not measured in this experiment, highly insulating windows (triple-pane in this experiment) also have the potential to significantly reduce the noise transmittance through windows compared to standard double-pane windows. The metered data taken in the Lab Homes and data analysis presented here represent 70 days of data taken during the 2012 heating season. As such, the savings from highly insulating windows in the experimental home (Lab Home B) compared to the standard double-pane clear glass windows in the baseline home (Lab Home A) are only a portion of the energy savings expected from a year-long experiment that would include a cooling season. The cooling season experiment will take place in the homes in the summer of 2012, and results of that experiment will be reported in a subsequent report available to all stakeholders.« less

The All-Asteroids Lab Course: Kepler's Laws, Collisions, And Authentic Undergraduate Research

NASA Astrophysics Data System (ADS)

Puckett, Andrew W.; Rector, T. A.

2010-01-01

We have developed a 12-week undergraduate laboratory sequence based entirely on asteroids and the hazards they pose. This curriculum has been designed primarily for use in an introductory Solar System Astronomy course, but it can be broken into smaller segments for a variety of course scenarios and educational goals. The course begins with a four-lab sequence based on our new online Java applet OrbitMaster, (adapted from AstroArts’ OrbitViewer under the GNU General Public License). OrbitMaster allows the user to alter an asteroid's orbital parameters and monitor its position and speed relative to both Sun and Earth. It also detects close approaches and collisions with Earth, and calculates revised speeds due to Earth's gravity. Students are able to confirm Kepler's laws, examine orbital properties that produce impacts, discover the kinetic energy-crater size relationship, understand the regional/global consequences of impacts, and experiment with deflection strategies. A three-lab sequence follows that examines the orbit-refinement and changing impact odds of 2007 WD5, which briefly had a 4% chance of hitting Mars in 2008. These labs introduce software that allows students to make astrometric measurements, fit orbital parameters, and predict future positions and uncertainties. They then use these tools in a four-lab research project to improve their own asteroids’ orbits, using images from the SDSS and WIYN 0.9-meter telescopes. Their work culminates in a presentation to their peers and submission of their astrometric measurements to the Minor Planet Center for publication. This effort is part of our NSF CCLI grant to develop Research Based Science Education (RBSE) curricula for non-majors. We have designed six projects that allow students to learn science by actually doing science. These projects are now being tested at six institutions around the country, and will eventually be distributed to a national audience.

Portrait of Dr. Von Braun with Walt Disney, 1954.

NASA Technical Reports Server (NTRS)

1954-01-01

Marshall Center Director Dr. Wernher Von Braun is pictured with Walt Disney during a visit to the Marshall Space Flight Center in 1954. In the 1950s, Dr. Von Braun while working in California on the Saturn project, also worked with Disney studios as a technical director in making three films about Space Exploration for television. Disney's tour of Marshall in 1965 was Von Braun's hope for a renewed public interest in the future of the Space Program at NASA.

Microsoft Licenses Berkeley Lab's Home Energy Saver Code for Its Energy

Science.gov Websites

-based tool for calculating energy use in residential buildings. About one million people visit the Home Management Software | Berkeley Lab Berkeley Lab A-Z Index Directory Submit Web People Navigation Berkeley Lab Search Submit Web People Close About the Lab Leadership/Organization Calendar News

HLA DR phenotypic frequencies and genetic risk of Type 1 diabetes in west region of Algeria, Tlemcen

PubMed Central

Aribi, Mourad; Moulessehoul, Soraya; Benabadji, Ahmed-Bakir; Kendoucitani, Mohammed

2004-01-01

Background The main genomic region controlling the predisposition to type 1 diabetes is the Human Leukocyte Antigens (HLA) class II of the major histocompatibility complex. Association with different HLA types depends also on the studied populations. In our investigation, we tried to measure the phenotypic HLA class II association frequencies of DR3 and/or DR4 antigens, using a serologic method called microlymphocytotoxicity analysis, in diabetic and nondiabetic (ND) subjects originating from the west-Algerian region of Tlemcen. The aim of the present study was to determine which HLA DR antigens represent a high susceptibility to develop the disease in this area. Using a case-control retrospective study design, we randomly recruited ninety-one related subjects, 39 type 1 diabetics and 52 ND as controls, at the Internal Medicine Board of Medical Centre University of Tlemcen. Results DR3 antigen frequencies were comparable between the type 1 diabetics and the ND subjects and showed no association with the disease (p = 1.000, OR = 0.95), whereas DR4 and DR3DR4 antigens were associated with susceptibility to develop type 1 diabetes (DR4; OR = 2.10, DR3DR4; OR = 1.30). Also, no incidence for DR3 (p = 0.2646) or DR3DR4 (p = 0.0699) antigen frequencies was related to the sex ratio. However, significant differences in HLA DR4 frequencies between type 1 diabetics and ND were found to be related to sex (p = 0.0085). Conclusion Taken together, our investigation showed that the strongest association with type 1 diabetes was noticed in the presence of HLA DR4 antigens followed by DR3DR4 antigens. This study highlighted a characteristic of Tlemcen population; a history of consanguineous marriages. Association studies between the disease and genetic polymorphisms should be undertaken in a population where consanguinity is more limited to reduce confounding in result interpretations. PMID:15331022

Reducing unnecessary lab testing in the ICU with artificial intelligence.

PubMed

Cismondi, F; Celi, L A; Fialho, A S; Vieira, S M; Reti, S R; Sousa, J M C; Finkelstein, S N

2013-05-01

To reduce unnecessary lab testing by predicting when a proposed future lab test is likely to contribute information gain and thereby influence clinical management in patients with gastrointestinal bleeding. Recent studies have demonstrated that frequent laboratory testing does not necessarily relate to better outcomes. Data preprocessing, feature selection, and classification were performed and an artificial intelligence tool, fuzzy modeling, was used to identify lab tests that do not contribute an information gain. There were 11 input variables in total. Ten of these were derived from bedside monitor trends heart rate, oxygen saturation, respiratory rate, temperature, blood pressure, and urine collections, as well as infusion products and transfusions. The final input variable was a previous value from one of the eight lab tests being predicted: calcium, PTT, hematocrit, fibrinogen, lactate, platelets, INR and hemoglobin. The outcome for each test was a binary framework defining whether a test result contributed information gain or not. Predictive modeling was applied to recognize unnecessary lab tests in a real world ICU database extract comprising 746 patients with gastrointestinal bleeding. Classification accuracy of necessary and unnecessary lab tests of greater than 80% was achieved for all eight lab tests. Sensitivity and specificity were satisfactory for all the outcomes. An average reduction of 50% of the lab tests was obtained. This is an improvement from previously reported similar studies with average performance 37% by [1-3]. Reducing frequent lab testing and the potential clinical and financial implications are an important issue in intensive care. In this work we present an artificial intelligence method to predict the benefit of proposed future laboratory tests. Using ICU data from 746 patients with gastrointestinal bleeding, and eleven measurements, we demonstrate high accuracy in predicting the likely information to be gained from proposed future

Reducing unnecessary lab testing in the ICU with artificial intelligence

PubMed Central

Cismondi, F.; Celi, L.A.; Fialho, A.S.; Vieira, S.M.; Reti, S.R.; Sousa, J.M.C.; Finkelstein, S.N.

2017-01-01

Objectives To reduce unnecessary lab testing by predicting when a proposed future lab test is likely to contribute information gain and thereby influence clinical management in patients with gastrointestinal bleeding. Recent studies have demonstrated that frequent laboratory testing does not necessarily relate to better outcomes. Design Data preprocessing, feature selection, and classification were performed and an artificial intelligence tool, fuzzy modeling, was used to identify lab tests that do not contribute an information gain. There were 11 input variables in total. Ten of these were derived from bedside monitor trends heart rate, oxygen saturation, respiratory rate, temperature, blood pressure, and urine collections, as well as infusion products and transfusions. The final input variable was a previous value from one of the eight lab tests being predicted: calcium, PTT, hematocrit, fibrinogen, lactate, platelets, INR and hemoglobin. The outcome for each test was a binary framework defining whether a test result contributed information gain or not. Patients Predictive modeling was applied to recognize unnecessary lab tests in a real world ICU database extract comprising 746 patients with gastrointestinal bleeding. Main results Classification accuracy of necessary and unnecessary lab tests of greater than 80% was achieved for all eight lab tests. Sensitivity and specificity were satisfactory for all the outcomes. An average reduction of 50% of the lab tests was obtained. This is an improvement from previously reported similar studies with average performance 37% by [1–3]. Conclusions Reducing frequent lab testing and the potential clinical and financial implications are an important issue in intensive care. In this work we present an artificial intelligence method to predict the benefit of proposed future laboratory tests. Using ICU data from 746 patients with gastrointestinal bleeding, and eleven measurements, we demonstrate high accuracy in predicting the

Latest results from FROST at Jefferson Lab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ritchie, Barry G.

2014-06-01

The spectrum of broad and overlapping nucleon excitations can be greatly clarified by use of a polarized photon beam incident on a polarized target in meson photoproduction experiments. At Jefferson Lab, a program of such measurements has made use of the Jefferson Lab FROzen Spin Target (FROST). An overview of preliminary results are presented.

Gaming Sea-based Multinational HA/DR Operations at PACOM Amphibious Leaders Symposium 2016

DTIC Science & Technology

2016-11-01

DISTRIBUTION STATEMENT A. Approved for public release: distribution unlimited. Gaming Sea-based Multinational HA/DR Operations...Marine Corps photo by Cpl. Wesley Timm. Approved by: November 2016 Dr. E.D. McGrady Director, Integration and Gaming Advanced Technology and...TYPE Final2 3. DATES COVERED (From - To) 4. TITLE AND SUBTITLE Gaming Seabased Multinational HA/DR Operations at PACOM 5a. CONTRACT NUMBER N00014-16

Dr. Sholom Wacholder - In their own words

Cancer.gov

Dr. Sholom Wacholder, a biostatistician in the NCI Division of Cancer Epidemiology and Genetics, discusses his role on a human papillomavirus vaccine clinical trial. From the archives of the NCI Cancer Bulletin - 2010.

STS-133 crew training in VR Lab with replacement crew member Steve Bowen

NASA Image and Video Library

2011-01-24

JSC2011-E-006293 (24 Jan. 2011) --- NASA astronaut Michael Barratt, STS-133 mission specialist, uses the virtual reality lab in the Space Vehicle Mock-up Facility at NASA's Johnson Space Center to train for some of his duties aboard the space shuttle and space station. This type of computer interface, paired with virtual reality training hardware and software, helps to prepare crew members for dealing with space station elements. Photo credit: NASA or National Aeronautics and Space Administration

The Mysterious Death: An HPLC Lab Experiment. An Undergraduate Forensic Lab

ERIC Educational Resources Information Center

Beussman, Douglas J.

2007-01-01

A high-performance liquid chromatography (HPLC) laboratory experiment based on the separation of four prescription drugs (disopyramide, lidocaine, procainamide, and quinidine) is presented. The experiment is set within the forensic science context of the discovery of a patient's mysterious death where a drug overdose is suspected. Each lab group…

Sodium Blood Test: MedlinePlus Lab Test Information

MedlinePlus

... Lab Tests Online [Internet]. American Association for Clinical Chemistry; c2001–2017. Cirrhosis; [updated 2017 Jan 8; cited ... Lab Tests Online [Internet]. American Association for Clinical Chemistry; c2001–2017. Electrolytes: Common Questions [updated 2015 Dec ...

Maniac Talk - Dr. Eugenia Kalnay

NASA Image and Video Library

2015-03-31

Eugenia Kalnay Maniac Lecture, March 31, 2015 Dr. Eugenia Kalnay, Distinguished University Professor and the first woman to get a doctorate in Meteorology from MIT, presented a Maniac Talk entitled, "Sheer luck: How I stumbled my way through a fantastic scientific career." Eugenia shared her life and times at the University of Buenos Aires, MIT, NASA, NOAA and University of Maryland, infused with dreams from her mother.

Maniac Talk - Dr. Anne Thompson

NASA Image and Video Library

2014-04-30

Anne Thompson Maniac Lecture, 30 April 2014 NASA climate scientist Dr. Anne Thompson presented a Maniac Talk entitled "A Career in Many Ozone Layers." Anne shared some of her long scientific career both as a researcher at Goddard and Meteorology professor at Penn State. She also described some of the problems she has worked on and tried to convey an enthusiasm for Earth Observations

Maniac Talk - Dr. Anne Douglass

NASA Image and Video Library

2013-03-27

Anne Douglass Maniac Lecture, 27 March, 2013 NASA climate scientist Dr. Anne Douglass presented a Maniac Talk entitled "Satellite Observations - the Touchstone of Atmospheric Modeling." Anne shared some of her scientific career that is filled with unexpected twists and turns and even a few blind alleys, but most important her passion in satellite measurements of ozone and other trace gases, which have been her touchstone.

Maniac Talk - Dr. Brian Dennis

NASA Image and Video Library

2014-09-24

Brian Dennis Maniac Lecture, September 24, 2014 NASA Solar Physicist Dr. Brian Dennis presented a Maniac Talk entitled "From Picking Potatoes to Measuring the Biggest Bangs in the Solar System -- Always a Farm Boy!" Brian described his formative years in England, then summarized our present understanding of how solar flares work and reviewed possible advances in instrumentation that could lead to major breakthroughs in the future.

Maniac Talk - Dr. Jack Kaye

NASA Image and Video Library

2014-07-23

Jack Kaye Maniac Lecture, July 23, 2014 Dr. Jack Kaye, Associate Director for Research at NASA Headquarters presented a Maniac Talk entitled, "An Unlikely but Rewarding Journey--From Quantum Chemistry to Earth Science Research Program Leadership." Jack took stock of his 30+ years at NASA, noting the people, opportunities, lessons learned, and choices that helped him get to where he is today and accomplish what he have.

Undergraduate HBCU Student Summer Training Program for Developing Nanomedicines to Treat Prostate Cancers

DTIC Science & Technology

2017-10-01

pancreatic cancer cells. 3. Sequoyah Bennett Sequoyah worked in the lab of Dr. Surinder Batra, Department of Biochemistry and Molecular Biology , College...the lab of Dr. Kaustubh Datta, Department of Biochemistry and Molecular Biology at the University of Nebraska Medical Center. During that time, Ciera...following the therapeutic intervention or prostate cancer. Furthermore, she learned the basic cell culture and molecular biology techniques. (2016) 1

Integrating Multiple On-line Knowledge Bases for Disease-Lab Test Relation Extraction.

PubMed

Zhang, Yaoyun; Soysal, Ergin; Moon, Sungrim; Wang, Jingqi; Tao, Cui; Xu, Hua

2015-01-01

A computable knowledge base containing relations between diseases and lab tests would be a great resource for many biomedical informatics applications. This paper describes our initial step towards establishing a comprehensive knowledge base of disease and lab tests relations utilizing three public on-line resources. LabTestsOnline, MedlinePlus and Wikipedia are integrated to create a freely available, computable disease-lab test knowledgebase. Disease and lab test concepts are identified using MetaMap and relations between diseases and lab tests are determined based on source-specific rules. Experimental results demonstrate a high precision for relation extraction, with Wikipedia achieving the highest precision of 87%. Combining the three sources reached a recall of 51.40%, when compared with a subset of disease-lab test relations extracted from a reference book. Moreover, we found additional disease-lab test relations from on-line resources, indicating they are complementary to existing reference books for building a comprehensive disease and lab test relation knowledge base.

LIVING LAB: User-Driven Innovation for Sustainability

ERIC Educational Resources Information Center

Liedtke, Christa; Welfens, Maria Jolanta; Rohn, Holger; Nordmann, Julia

2012-01-01

Purpose: The purpose of this paper is to summarize and discuss the results from the LIVING LAB design study, a project within the 7th Framework Programme of the European Union. The aim of this project was to develop the conceptual design of the LIVING LAB Research Infrastructure that will be used to research human interaction with, and stimulate…

Optically Isolated Control of the MOCHI LabJet High Power Pulsed Plasma Experiment

NASA Astrophysics Data System (ADS)

Carroll, Evan; Quinley, Morgan; von der Linden, Jens; You, Setthivoine

2014-10-01

The MOCHI LabJet experiment designed to investigate the dynamics of astrophysical jets at the University of Washington, requires high energy pulsed power supplies for plasma generation and sustainment. Two 600 μ F, 10 kV DC, pulse forming, power supplies have been specifically developed for this application. For safe and convenient user operation, the power supplies are controlled remotely with optical isolation. Three input voltage signals are required for relay actuation, adjusting bank charging voltage, and to fire the experiment: long duration DC signals, long duration user adjustable DC signals and fast trigger pulses with < μ s rise times. These voltage signals are generated from National Instruments timing cards via LabVIEW and are converted to optical signals by coupling photodiodes with custom electronic circuits. At the experiment, the optical signals are converted back to usable voltage signals using custom circuits. These custom circuits and experimental set-up are presented. This work is supported by US DOE Grant DE-SC0010340.

A portrait of the extreme solar system object 2012 DR30

NASA Astrophysics Data System (ADS)

Kiss, Cs.; Szabó, Gy.; Horner, J.; Conn, B. C.; Müller, T. G.; Vilenius, E.; Sárneczky, K.; Kiss, L. L.; Bannister, M.; Bayliss, D.; Pál, A.; Góbi, S.; Verebélyi, E.; Lellouch, E.; Santos-Sanz, P.; Ortiz, J. L.; Duffard, R.; Morales, N.

2013-07-01

2012 DR30 is a recently discovered solar system object on a unique orbit, with a high eccentricity of 0.9867, a perihelion distance of 14.54 AU, and a semi-major axis of 1109 AU, in this respect outscoring the vast majority of trans-Neptunian objects (TNOs). We performed Herschel/PACS and optical photometry to uncover the sizeand albedo of 2012 DR30, together with its thermal and surface properties. The body is 185 km in diameter and has a relatively low V-band geometric albedo of ~8%. Although the colours of the object indicate that 2012 DR30 is an RI taxonomy class TNO or Centaur, we detected an absorption feature in the Z-band that is uncommon among these bodies. A dynamical analysis of the target's orbit shows that 2012 DR30 moves on a relatively unstable orbit and was most likely only recently placed on its current orbit from the most distant and still highly unexplored regions of the solar system. If categorised on dynamical grounds 2012 DR30 is the largest Damocloid and/or high inclination Centaur observed so far. Herschel is an ESA space observatory with science instruments provided by European-led Principal Investigator consortia and with important participation from NASA.Appendices are available in electronic form at http://www.aanda.org

Gaia: Mapping the Milky Way: The Scientific Promise of Gaia DR2

NASA Astrophysics Data System (ADS)

Walton, Nicholas; ESA Gaia, Data Processing and Analysis Consortium (DPAC)

2018-06-01

The ESA Gaia mission will release its first major all sky astrometric catalogue (Gaia DR2), of more than 1.3 billion stars in our Galaxy, on 25 April 2018.This presentation will provide an overview of the Gaia mission, focussing on the significant scientific potential of the Gaia DR2 release. This is based on 22 months of input data and allows for a full Gaia stand alone astrometric solution, including parallaxes and proper motions, of over 1.3 billion sources. The astrometric uncertainties in Gaia DR2 will be at the level of tens of micro-arcsec for sources G<15.The Gaia DR2 release provides not only high precision full five parameter astrometry, but also a complete photometric catalogue of the sources on an all sky homogeneous photometric system in the Gaia G band and broad bands G_BP and G_RP. The release will include median radial velocities for more than six million stars (brighter that G_RVS = 12) together with a set of astrophysical parameters (including stellar temperatures) for some 150 million stars. Finally the Gaia DR2 release will include a set of additional data products including the light curves of more than half a million variable stars, and the positions of more than thirteen thousand objects in our Solar System.Together with the Gaia DR2 data products and associated release documentation, a small number of performance verification papers, using Gaia DR2 data only to provide new insights into a number of key areas of Gaia science, will be published in a special edition of A&A. These will provide demonstrations of the scientific potential of the Gaia DR2 catalogue, and also highlight some of the issues and limitations involved in the use of the Gaia DR2 data.The Gaia mission and Gaia Data Releases are made possible through the dedication and expertise of the community scientists and engineers involved in the design, construction, and operation of Gaia (led by ESA) and the collaboration of some 450 scientists and software engineers responsible for

The experiment editor: supporting inquiry-based learning with virtual labs

NASA Astrophysics Data System (ADS)

Galan, D.; Heradio, R.; de la Torre, L.; Dormido, S.; Esquembre, F.

2017-05-01

Inquiry-based learning is a pedagogical approach where students are motivated to pose their own questions when facing problems or scenarios. In physics learning, students are turned into scientists who carry out experiments, collect and analyze data, formulate and evaluate hypotheses, and so on. Lab experimentation is essential for inquiry-based learning, yet there is a drawback with traditional hands-on labs in the high costs associated with equipment, space, and maintenance staff. Virtual laboratories are helpful to reduce these costs. This paper enriches the virtual lab ecosystem by providing an integrated environment to automate experimentation tasks. In particular, our environment supports: (i) scripting and running experiments on virtual labs, and (ii) collecting and analyzing data from the experiments. The current implementation of our environment supports virtual labs created with the authoring tool Easy Java/Javascript Simulations. Since there are public repositories with hundreds of freely available labs created with this tool, the potential applicability to our environment is considerable.

Electron Microscopy Lab

Science.gov Websites

Facilities Science Pillars Research Library Science Briefs Science News Science Highlights Lab Organizations Science Programs Applied Energy Programs Civilian Nuclear Energy Programs Laboratory Directed Research Science Seaborg Institute Fellows Conferences Research Opportunities Center for Integrated

A LabVIEW Platform for Preclinical Imaging Using Digital Subtraction Angiography and Micro-CT.

PubMed

Badea, Cristian T; Hedlund, Laurence W; Johnson, G Allan

2013-01-01

CT and digital subtraction angiography (DSA) are ubiquitous in the clinic. Their preclinical equivalents are valuable imaging methods for studying disease models and treatment. We have developed a dual source/detector X-ray imaging system that we have used for both micro-CT and DSA studies in rodents. The control of such a complex imaging system requires substantial software development for which we use the graphical language LabVIEW (National Instruments, Austin, TX, USA). This paper focuses on a LabVIEW platform that we have developed to enable anatomical and functional imaging with micro-CT and DSA. Our LabVIEW applications integrate and control all the elements of our system including a dual source/detector X-ray system, a mechanical ventilator, a physiological monitor, and a power microinjector for the vascular delivery of X-ray contrast agents. Various applications allow cardiac- and respiratory-gated acquisitions for both DSA and micro-CT studies. Our results illustrate the application of DSA for cardiopulmonary studies and vascular imaging of the liver and coronary arteries. We also show how DSA can be used for functional imaging of the kidney. Finally, the power of 4D micro-CT imaging using both prospective and retrospective gating is shown for cardiac imaging.

A LabVIEW Platform for Preclinical Imaging Using Digital Subtraction Angiography and Micro-CT

PubMed Central

Badea, Cristian T.; Hedlund, Laurence W.; Johnson, G. Allan

2013-01-01

CT and digital subtraction angiography (DSA) are ubiquitous in the clinic. Their preclinical equivalents are valuable imaging methods for studying disease models and treatment. We have developed a dual source/detector X-ray imaging system that we have used for both micro-CT and DSA studies in rodents. The control of such a complex imaging system requires substantial software development for which we use the graphical language LabVIEW (National Instruments, Austin, TX, USA). This paper focuses on a LabVIEW platform that we have developed to enable anatomical and functional imaging with micro-CT and DSA. Our LabVIEW applications integrate and control all the elements of our system including a dual source/detector X-ray system, a mechanical ventilator, a physiological monitor, and a power microinjector for the vascular delivery of X-ray contrast agents. Various applications allow cardiac- and respiratory-gated acquisitions for both DSA and micro-CT studies. Our results illustrate the application of DSA for cardiopulmonary studies and vascular imaging of the liver and coronary arteries. We also show how DSA can be used for functional imaging of the kidney. Finally, the power of 4D micro-CT imaging using both prospective and retrospective gating is shown for cardiac imaging. PMID:27006920

ORAC-DR -- integral field spectroscopy data reduction

NASA Astrophysics Data System (ADS)

Todd, Stephen

ORAC-DR is a general-purpose automatic data-reduction pipeline environment. This document describes its use to reduce integral field unit (IFU) data collected at the United Kingdom Infrared Telescope (UKIRT) with the UIST instrument.

Star Formation in the DR21 Region (B)

NASA Technical Reports Server (NTRS)

2004-01-01

[figure removed for brevity, see original site] Annotated mosaic

Hidden behind a shroud of dust in the constellation Cygnus is an exceptionally bright source of radio emission called DR21. Visible light images reveal no trace of what is happening in this region because of heavy dust obscuration. In fact, visible light is attenuated in DR21 by a factor of more than 10,000,000,000,000,000,000,000,000,000,000,000,000,000 (ten thousand trillion heptillion).

New images from NASA's Spitzer Space Telescope allow us to peek behind the cosmic veil and pinpoint one of the most massive natal stars yet seen in our Milky Way galaxy. The never-before-seen star is 100,000 times as bright as the Sun. Also revealed for the first time is a powerful outflow of hot gas emanating from this star and bursting through a giant molecular cloud.

The upper image is a large-scale mosaic assembled from individual photographs obtained with the InfraRed Array Camera (IRAC) aboard Spitzer. The image covers an area about two times that of a full moon. The mosaic is a composite of images obtained at mid-infrared wavelengths of 3.6 microns (blue), 4.5 microns (green), 5.8 microns (orange) and 8 microns (red). The brightest infrared cloud near the top center corresponds to DR21, which presumably contains a cluster of newly forming stars at a distance of 10,000 light-years.

Protruding out from DR21 toward the bottom left of the image is a gaseous outflow (green), containing both carbon monoxide and molecular hydrogen. Data from the Spitzer spectrograph, which breaks light into its constituent individual wavelengths, indicate the presence of hot steam formed as the outflow heats the surrounding molecular gas. Outflows are physical signatures of processes that create supersonic beams, or jets, of gas. They are usually accompanied by discs of material around the new star, which likely contain the materials from which future planetary systems are formed. Additional newborn stars

A Case Study of a High School Fab Lab

NASA Astrophysics Data System (ADS)

Lacy, Jennifer E.

This dissertation examines making and design-based STEM education in a formal makerspace. It focuses on how the design and implementation of a Fab Lab learning environment and curriculum affect how instructors and students see themselves engaging in science, and how the Fab Lab relates to the social sorting practices that already take place at North High School. While there is research examining design-based STEM education in informal and formal learning environments, we know little about how K-12 teachers define STEM in making activities when no university or museum partnership exists. This study sought to help fill this gap in the research literature. This case study of a formal makerspace followed instructors and students in one introductory Fab Lab course for one semester. Additional observations of an introductory woodworking course helped build the case and set it into the school context, and provided supplementary material to better understand the similarities and differences between the Fab Lab course and a more traditional design-based learning course. Using evidence from observational field notes, participant interviews, course materials, and student work, I found that the North Fab Lab relies on artifacts and rhetoric symbolic of science and STEM to set itself apart from other design-based courses at North High School. Secondly, the North Fab Lab instructors and students were unable to explain how what they were doing in the Fab Lab was science, and instead relied on vague and unsupported claims related to interdisciplinary STEM practices and dated descriptions of science. Lastly, the design and implementation of the Fab Lab learning environment and curriculum and its separation from North High School's low tech, design-based courses effectively reinforced social sorting practices and cultural assumptions about student work and intelligence.

NREL: Speeches - Nation's Energy Future at Risk

Science.gov Websites

Energy Future at Risk, National Lab Director Says For more information contact: George Douglas, 303 -275-4096 e:mail: George Douglas Washington, D.C., July 27, 1999 — America must invest in its energy future now, Richard Truly, director of the U.S. Department of Energy's National Renewable Energy

Final report for Texas A&M University Group Contribution to DE-FG02-09ER25949/DE-SC0002505: Topology for Statistical Modeling of Petascale Data (and ASCR-funded collaboration between Sandia National Labs, Texas A&M University and University of Utah)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rojas, Joseph Maurice

We summarize the contributions of the Texas A\\&M University Group to the project (DE-FG02-09ER25949/DE-SC0002505: Topology for Statistical Modeling of Petascale Data - an ASCR-funded collaboration between Sandia National Labs, Texas A\\&M U, and U Utah) during 6/9/2011 -- 2/27/2013.

The History of Science and Technology at Bell Labs

NASA Astrophysics Data System (ADS)

Bishop, David

2008-03-01

Over the last 80 years, Bell Labs has been one of the most scientifically and technologically productive research labs in the world. Inventions such as the transistor, laser, cell phone, solar cell, negative feedback amplifier, communications satellite and many others were made there. Scientific breakthroughs such as discovery of the Big Bang, the wave nature of the electron, electron localization and the fractional quantum hall effect were also made there making Bell Labs almost unique in terms of large impacts in both science and technology. In my talk, I will discuss the history of the lab, talk about the present and give some suggestions for how I see it evolving into the future.

Towards a Flexible Language Lab for Community Colleges.

ERIC Educational Resources Information Center

Conway, Diana

1992-01-01

Suggestions are offered for ways to modify a typical community college language laboratory to serve diverse student needs. The discussion is based on experiences of Anchorage Community College, which modeled its lab on a learning resources center rather than a traditional lab. (LB)

Introducing ADS Labs

NASA Astrophysics Data System (ADS)

Accomazzi, Alberto; Henneken, E.; Grant, C. S.; Kurtz, M. J.; Di Milia, G.; Luker, J.; Thompson, D. M.; Bohlen, E.; Murray, S. S.

2011-05-01

ADS Labs is a platform that ADS is introducing in order to test and receive feedback from the community on new technologies and prototype services. Currently, ADS Labs features a new interface for abstract searches, faceted filtering of results, visualization of co-authorship networks, article-level recommendations, and a full-text search service. The streamlined abstract search interface provides a simple, one-box search with options for ranking results based on a paper relevancy, freshness, number of citations, and downloads. In addition, it provides advanced rankings based on collaborative filtering techniques. The faceted filtering interface allows users to narrow search results based on a particular property or set of properties ("facets"), allowing users to manage large lists and explore the relationship between them. For any set or sub-set of records, the co-authorship network can be visualized in an interactive way, offering a view of the distribution of contributors and their inter-relationships. This provides an immediate way to detect groups and collaborations involved in a particular research field. For a majority of papers in Astronomy, our new interface will provide a list of related articles of potential interest. The recommendations are based on a number of factors, including text similarity, citations, and co-readership information. The new full-text search interface allows users to find all instances of particular words or phrases in the body of the articles in our full-text archive. This includes all of the scanned literature in ADS as well as a select portion of the current astronomical literature, including ApJ, ApJS, AJ, MNRAS, PASP, A&A, and soon additional content from Springer journals. Fulltext search results include a list of the matching papers as well as a list of "snippets" of text highlighting the context in which the search terms were found. ADS Labs is available at http://adslabs.org

Time Trials--An AP Physics Challenge Lab

ERIC Educational Resources Information Center

Jones, David

2009-01-01

I have come to the conclusion that for high school physics classroom and laboratory experiences, simpler is better! In this paper I describe a very simple and effective lab experience that my AP students have thoroughly enjoyed year after year. I call this lab exercise "Time Trials." The experiment is simple in design and it is a lot of fun for…

The life and contribution of Dr. Ronald Gitelman: a pioneer of modern chiropractic science.

PubMed

Vernon, Howard

2013-03-01

The life and contribution to chiropractic science of Dr. Ronald Gitelman is reviewed. Sources for this article included review of the notes prepared by Dr. Joseph Keating in his "biography" of the Canadian Memorial Chiropractic College (CMCC); review of the important articles published by Dr. Gitelman; review of the important projects undertaken by him along with various colleagues; notes from reminiscences obtained from many of these colleagues and discussions with his family. Dr. Gitelman's academic career spanned from 1963 to the late 1980's. During that time, he made foundational contributions to the development of chiropractic science including: developing the Archives (1974), the first collection of scientific articles supporting chiropractic science (which was subsequently published as the Chiropractic Archives Research Collection (CRAC)); delivering one of the few chiropractic papers at the seminal NINCDS conference (1975) and, developing the collaboration between CMCC and Dr. Kirkaldy-Willis at the University of Saskatoon (1976). He practiced in Toronto from 1961 to 2007. Dr. Gitelman was a pioneer in the development of chiropractic science. He died on October 7, 2012.

Elemental Chem Lab

ERIC Educational Resources Information Center

Franco Mariscal, Antonio Joaquin

2008-01-01

This educative material uses the symbols of 45 elements to spell the names of 32 types of laboratory equipment usually found in chemical labs. This teaching material has been divided into three puzzles according to the type of the laboratory equipment: (i) glassware as reaction vessels or containers; (ii) glassware for measuring, addition or…

Lab with Dad

ERIC Educational Resources Information Center

Havers, Brenda; Delmotte, Karen

2012-01-01

Family science nights are fantastic, but planning one can be overwhelming, especially when one considers the already overloaded schedule of a classroom teacher. To overcome this challenge, the authors--colleagues with a mutual love of science--developed a much simpler annual event called "Lab With Dad." The purpose was for one target age group of…

Maniac Talk - Dr. James Garvin

NASA Image and Video Library

2014-05-28

James Garvin Maniac Lecture, 28 May 2014 Dr. James Garvin, Chief Scientist, NASA Goddard Space Flight Center, presented a Maniac Talk entitled "From Brownian Motion to Mars, by way of hockey on the rocks." Jim shared how his passion for rocks and landscapes drove him to promote new remote sensing approaches for measuring their topologies and led to founding of the Mars Science Laboratory and its Curiosity Rover.

Death receptors DR6 and TROY regulate brain vascular development.

PubMed

Tam, Stephen J; Richmond, David L; Kaminker, Joshua S; Modrusan, Zora; Martin-McNulty, Baby; Cao, Tim C; Weimer, Robby M; Carano, Richard A D; van Bruggen, Nick; Watts, Ryan J

2012-02-14

Signaling events that regulate central nervous system (CNS) angiogenesis and blood-brain barrier (BBB) formation are only beginning to be elucidated. By evaluating the gene expression profile of mouse vasculature, we identified DR6/TNFRSF21 and TROY/TNFRSF19 as regulators of CNS-specific angiogenesis in both zebrafish and mice. Furthermore, these two death receptors interact both genetically and physically and are required for vascular endothelial growth factor (VEGF)-mediated JNK activation and subsequent human brain endothelial sprouting in vitro. Increasing beta-catenin levels in brain endothelium upregulate DR6 and TROY, indicating that these death receptors are downstream target genes of Wnt/beta-catenin signaling, which has been shown to be required for BBB development. These findings define a role for death receptors DR6 and TROY in CNS-specific vascular development. Copyright © 2012 Elsevier Inc. All rights reserved.

[Sexuality education on the Internet : From Dr. Sommer to Dr. Google].

PubMed

Döring, Nicola

2017-09-01

Female and male adolescents in Germany are increasingly using the Internet to find information about sexuality and sexual health. This review paper summarizes what we know about the status quo of online sexuality education in Germany.Based on a systematic literature review including 40 papers from international, peer-reviewed journals spanning 2010-2017, this paper first describes different aspects of the sexuality-related online search behavior of adolescents: its prevalence, predictors, topics and contexts. One main finding is the fact that adolescents use a computer or smartphone to type their sexuality-related questions into the search engine Google or the search engine of the video platform YouTube.Based on 54 online searches, this paper subsequently presents the kind of sexuality-related online content adolescents find if they ask "Dr. Google" for sexual advice; a collection of 1236 authentic sexuality-related questions of adolescents was used for this analysis. It turned out that online sexuality education offered by leading professional organizations like the BZgA ("Bundeszentrale für gesundheitliche Aufklärung") or pro familia was nearly invisible, while numerous other providers of online sex education consistently appeared in the top Google search results. Among them were the "Dr. Sommer" team of the youth magazine Bravo; online healthcare and advice portals; online forums; the online encyclopedia Wikipedia and, above all, sex education channels on YouTube. In this paper, the latter are presented in more detail for the first time.The third part of the paper addresses the quality of online sexual education over four main areas of quality evaluation. The presentation of the status quo ends with some recommendations both for future research and for sexuality education in practice.

Developing Nationally Competitive NASA Research Capability in West Virginia

NASA Technical Reports Server (NTRS)

Calzonetti, Frank J.

1997-01-01

In May, 1995 West Virginia EPSCOR was awarded $150,000 to support activities to develop research capabilities in West Virginia in support of the National Aeronautics and Space Administration (NASA). These funds were used to support three projects: 1) Information Processing and the Earth Observing System, directed by Dr. Stuart Tewksbury of West Virginia University; 2) Development of Optical Materials for Atmospheric Sensing Experiments, directed by Dr. Nancy Giles of West Virginia University; and 3) Development of Doppler Global Velocimeter (DGV) for Aeronautical and Combustion Studies, directed by Dr. John Kuhlman of West Virginia University. The funding provides the means to develop capability in each of these areas. This report summarizes the technical accomplishments in each project supported under this award.

Constructing the Components of a Lab Report Using Peer Review

ERIC Educational Resources Information Center

Berry, David E.; Fawkes, Kelli L.

2010-01-01

A protocol that emphasizes lab report writing using a piecemeal approach coupled with peer review is described. As the lab course progresses, the focus of the report writing changes sequentially through the abstract and introduction, the discussion, and the procedure. Two styles of lab programs are presented. One style rotates the students through…

Can Graduate Teaching Assistants Teach Inquiry-Based Geology Labs Effectively?

ERIC Educational Resources Information Center

Ryker, Katherine; McConnell, David

2014-01-01

This study examines the implementation of teaching strategies by graduate teaching assistants (GTAs) in inquiry-based introductory geology labs at a large research university. We assess the degree of inquiry present in each Physical Geology lab and compare and contrast the instructional practices of new and experienced GTAs teaching these labs. We…

Open web system of Virtual labs for nuclear and applied physics

NASA Astrophysics Data System (ADS)

Saldikov, I. S.; Afanasyev, V. V.; Petrov, V. I.; Ternovykh, M. Yu

2017-01-01

An example of virtual lab work on unique experimental equipment is presented. The virtual lab work is software based on a model of real equipment. Virtual labs can be used for educational process in nuclear safety and analysis field. As an example it includes the virtual lab called “Experimental determination of the material parameter depending on the pitch of a uranium-water lattice”. This paper included general description of this lab. A description of a database on the support of laboratory work on unique experimental equipment which is included this work, its concept development are also presented.

Inside Linden Lab

ERIC Educational Resources Information Center

Atkinson, Tom

2008-01-01

In this article, the author provides an overview of Second Life[trademark], or simply SL, which was developed at Linden Lab, a San Francisco-based corporation. SL is an online society within a threee-dimensional virtual world entirely built and owned by its residents, where they can explore, build, socialize and participate in their own economy.…

Introductory labs; what they don't, should, and can teach (and why)

NASA Astrophysics Data System (ADS)

Wieman, Carl

2016-03-01

Introductory physics labs are widely used and expensive. They have a wide variety of potential learning goals, but these are seldom specified and less often measured if they are achieved. We cover three different research projects on introductory labs: 1) We have done cognitive task analyses of both experimental research in physics and instructional labs. The striking differences explain much of the unhappiness expressed by students with labs: 2) We have measured the effectiveness of two introductory physics lab courses specifically intended to teach the physics content covered in standard introductory courses on mechanics and E & M. As measured by course exams, the benefit is 0 +/-2% for both. 3) We show how it is possible to use lab courses to teach students to correctly evaluate physical models with uncertain data. Such quantitative critical thinking is an important skill that is not learned in typical lab courses, but is well learned by our modified lab instruction.

Neural Plasticity and Neurorehabilitation Following Traumatic Brain Injury

DTIC Science & Technology

2010-10-01

for sectioning and staining . To date, the brains have been sectioned and one set stained for Nissl . Using the Nissl stained sections, Dorothy...all behavioral data. • Brains have been harvested and sent to Dr. Jones’ lab • Dr. Jones’ lab has sliced the brains and stained one set with Nissl ...remaining sets of brain sections are currently being stained with markers of plasticity using immunohistochemistry. We have completed immunohistochemical

Publish or perish: Dr Victor Webster and cardiazol treatment in Western Australia, 1937-1938.

PubMed

Martyr, Philippa

2017-10-01

To examine the role of Dr Victor Henry Webster (1905-1980) in the introduction of cardiazol therapy to Western Australia in November 1937. A range of primary and secondary sources were consulted. Webster experimented with cardiazol treatment at Heathcote Reception Home, and published his findings in April 1938, at the same time as Ellery and Lear, but was not able to publish his results in a nationally-recognised journal. As a result, his contribution to early cardiazol treatment in Australia has been largely forgotten. Webster made a genuine contribution to the introduction of cardiazol treatment in Australia, and his story illustrates the need to publish early findings of new physical therapies.

77 FR 42257 - General Conference Committee of the National Poultry Improvement Plan; Solicitation for Membership

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-18

...] General Conference Committee of the National Poultry Improvement Plan; Solicitation for Membership AGENCY... regional membership for the General Conference Committee of the National Poultry Improvement Plan. DATES... INFORMATION CONTACT: Dr. C. Stephen Roney, Senior Coordinator, National Poultry Improvement Plan, VS, APHIS...

DR-nm23 expression affects neuroblastoma cell differentiation, integrin expression, and adhesion characteristics.

PubMed

Amendola, R; Martinez, R; Negroni, A; Venturelli, D; Tanno, B; Calabretta, B; Raschellà, G

2001-01-01

Nm23 gene family has been associated with metastasis suppression and differentiation. We studied DR-nm23 during neuroblastoma cells differentiation. DR-nm23 expression increased after retinoic acid induction of differentiation in human cell lines SK-N-SH and LAN-5. In several cell lines, overexpression of DR-nm23 was associated with more differentiated phenotypes. SK-N-SH cells increased vimentin expression, increased deposition of collagen type IV, modulated integrin expression, and underwent growth arrest; the murine neuroblastoma cell line N1E-115 showed neurite outgrowth and a striking enhancement of beta1 integrin expression. Up-regulation of beta1 integrin was specifically responsible for the increase in the adhesion to collagen type I-coated plates. Finally, cells overexpressing DR-nm23 were unable to growth in soft agar. In conclusion, DR-nm23 expression is directly involved in differentiation of neuroblastoma cells, and its ability to affects the adhesion to extracellular substrates and to inhibit growth in soft agar suggests an involvement in the metastatic potential of neuroblastoma.

Behind the Scenes at Berkeley Lab - The Mechanical Fabrication Facility

ScienceCinema

Wells, Russell; Chavez, Pete; Davis, Curtis; Bentley, Brian

2018-04-16

Part of the Behind the Scenes series at Berkeley Lab, this video highlights the lab's mechanical fabrication facility and its exceptional ability to produce unique tools essential to the lab's scientific mission. Through a combination of skilled craftsmanship and precision equipment, machinists and engineers work with scientists to create exactly what's needed - whether it's measured in microns or meters.

New Features in ADS Labs

NASA Astrophysics Data System (ADS)

Accomazzi, Alberto; Kurtz, M. J.; Henneken, E. A.; Grant, C. S.; Thompson, D.; Di Milia, G.; Luker, J.; Murray, S. S.

2013-01-01

The NASA Astrophysics Data System (ADS) has been working hard on updating its services and interfaces to better support our community's research needs. ADS Labs is a new interface built on the old tried-and-true ADS Abstract Databases, so all of ADS's content is available through it. In this presentation we highlight the new features that have been developed in ADS Labs over the last year: new recommendations, metrics, a citation tool and enhanced fulltext search. ADS Labs has long been providing article-level recommendations based on keyword similarity, co-readership and co-citation analysis of its corpus. We have now introduced personal recommendations, which provide a list of articles to be considered based on a individual user's readership history. A new metrics interface provides a summary of the basic impact indicators for a list of records. These include the total and normalized number of papers, citations, reads, and downloads. Also included are some of the popular indices such as the h, g and i10 index. The citation helper tool allows one to submit a set of records and obtain a list of top 10 papers which cite and/or are cited by papers in the original list (but which are not in it). The process closely resembles the network approach of establishing "friends of friends" via an analysis of the citation network. The full-text search service now covers more than 2.5 million documents, including all the major astronomy journals, as well as physics journals published by Springer, Elsevier, the American Physical Society, the American Geophysical Union, and all of the arXiv eprints. The full-text search interface interface allows users and librarians to dig deep and find words or phrases in the body of the indexed articles. ADS Labs is available at http://adslabs.org

LabVIEW Interface for PCI-SpaceWire Interface Card

NASA Technical Reports Server (NTRS)

Lux, James; Loya, Frank; Bachmann, Alex

2005-01-01

This software provides a LabView interface to the NT drivers for the PCISpaceWire card, which is a peripheral component interface (PCI) bus interface that conforms to the IEEE-1355/ SpaceWire standard. As SpaceWire grows in popularity, the ability to use SpaceWire links within LabVIEW will be important to electronic ground support equipment vendors. In addition, there is a need for a high-level LabVIEW interface to the low-level device- driver software supplied with the card. The LabVIEW virtual instrument (VI) provides graphical interfaces to support all (1) SpaceWire link functions, including message handling and routing; (2) monitoring as a passive tap using specialized hardware; and (3) low-level access to satellite mission-control subsystem functions. The software is supplied in a zip file that contains LabVIEW VI files, which provide various functions of the PCI-SpaceWire card, as well as higher-link-level functions. The VIs are suitably named according to the matching function names in the driver manual. A number of test programs also are provided to exercise various functions.

Practical Clinical Training in Skills Labs: Theory and Practice

PubMed Central

Bugaj, T. J.; Nikendei, C.

2016-01-01

Today, skills laboratories or “skills labs”, i.e. specific practical skill training facilities, are a firmly established part of medical education offering the possibility of training clinical procedures in a safe and fault-forging environment prior to real life application at bedside or in the operating room. Skills lab training follows a structured teaching concept, takes place under supervision and in consideration of methodological-didactic concepts, ideally creating an atmosphere that allows the repeated, anxiety- and risk-free practice of targeted skills. In this selective literature review, the first section is devoted to (I) the development and dissemination of the skills lab concept. There follows (II) an outline of the underlying idea and (III) an analysis of key efficacy factors. Thereafter, (IV) the training method’s effectiveness and transference are illuminated, before (V) the use of student tutors, in the sense of peer-assisted-learning, in skills labs is discussed separately. Finally, (VI) the efficiency of the skills lab concept is analyzed, followed by an outlook on future developments and trends in the field of skills lab training. PMID:27579363

Georgetown University and Hampton University Prostate Cancer Undergraduate Fellowship Program

DTIC Science & Technology

2015-10-01

Tyanna Jones-Gray (Dr. Vicente Notario), Ms. Damara Miller (Dr. Eliot Rosen), Ms. Jasmine Hatcher-Moorman (Dr. MaryBeth Martin), and Mr. Isaiah Brown...undergraduate students: 1. The Hampton University undergraduates (Ms. Tyanna Jones-Gray, Ms. Damara Miller, Ms. Jasmine Hatcher-Moorman, and Mr...cancer progression. Dr. Martin’s lab has identified the environmental hormones referred to as metallo- hormones. In Dr. Martin’s laboratory, Jasmine

Thomas Jefferson National Accelerator Facility

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grames, Joseph; Higinbotham, Douglas; Montgomery, Hugh

The Thomas Jefferson National Accelerator Facility (Jefferson Lab) in Newport News, Virginia, USA, is one of ten national laboratories under the aegis of the Office of Science of the U.S. Department of Energy (DOE). It is managed and operated by Jefferson Science Associates, LLC. The primary facility at Jefferson Lab is the Continuous Electron Beam Accelerator Facility (CEBAF) as shown in an aerial photograph in Figure 1. Jefferson Lab was created in 1984 as CEBAF and started operations for physics in 1995. The accelerator uses superconducting radio-frequency (srf) techniques to generate high-quality beams of electrons with high-intensity, well-controlled polarization. Themore » technology has enabled ancillary facilities to be created. The CEBAF facility is used by an international user community of more than 1200 physicists for a program of exploration and study of nuclear, hadronic matter, the strong interaction and quantum chromodynamics. Additionally, the exceptional quality of the beams facilitates studies of the fundamental symmetries of nature, which complement those of atomic physics on the one hand and of high-energy particle physics on the other. The facility is in the midst of a project to double the energy of the facility and to enhance and expand its experimental facilities. Studies are also pursued with a Free-Electron Laser produced by an energy-recovering linear accelerator.« less

Caffeine content of prepackaged national-brand and private-label carbonated beverages.

PubMed

Chou, K-H; Bell, L N

2007-08-01

Caffeine is a well-known stimulant that is added as an ingredient to various carbonated soft drinks. Due to its stimulatory and other physiological effects, individuals desire to know the exact amount of caffeine consumed from these beverages. This study analyzed the caffeine contents of 56 national-brand and 75 private-label store-brand carbonated beverages using high-performance liquid chromatography. Caffeine contents ranged from 4.9 mg/12 oz (IGA Cola) to 74 mg/12 oz (Vault Zero). Some of the more common national-brand carbonated beverages analyzed in this study with their caffeine contents were Coca-Cola (33.9 mg/12 oz), Diet Coke (46.3 mg/12 oz), Pepsi (38.9 mg/12 oz), Diet Pepsi (36.7 mg/12 oz), Dr Pepper (42.6 mg/12 oz), Diet Dr Pepper (44.1 mg/12 oz), Mountain Dew (54.8 mg/12 oz), and Diet Mountain Dew (55.2 mg/12 oz). The Wal-Mart store-brand beverages with their caffeine contents were Sam's Cola (12.7 mg/12 oz), Sam's Diet Cola (13.3 mg/12 oz), Dr Thunder (30.6 mg/12 oz), Diet Dr Thunder (29.9 mg/12 oz), and Mountain Lightning (46.5 mg/12 oz). Beverages from 14 other stores were also analyzed. Most store-brand carbonated beverages were found to contain less caffeine than their national-brand counterparts. The wide range of caffeine contents in carbonated beverages indicates that consumers would benefit from the placement of caffeine values on food labels.

Stream piracy in the Black Hills: A geomorphology lab exercise

USGS Publications Warehouse

Zaprowski, B.J.; Evenson, E.B.; Epstein, J.B.

2002-01-01

The Black Hills of South Dakota exhibits many fine examples of stream piracy that are very suitable for teaching geomorphology lab exercises. This lab goes beyond standard topographic map interpretation by using geologic maps, well logs, gravel provenance and other types of data to teach students about stream piracy. Using a step-by-step method in which the lab exercises ramp up in difficulty, students hone their skills in deductive reasoning and data assimilation. The first exercises deal with the identification of stream piracy at a variety of spatial scales and the lab culminates with an exercise on landscape evolution and drainage rearrangement.

Creative Science Teaching Labs: New Dimensions in CPD

ERIC Educational Resources Information Center

Chappell, Kerry; Craft, Anna

2009-01-01

This paper offers analysis and evaluation of "Creative Science Teaching (CST) Labs III", a unique and immersive approach to science teachers' continuing professional development (CPD) designed and run by a London-based organisation, Performing Arts Labs (PAL), involving specialists from the arts, science and technology as integral. Articulating…

Online Writing Labs as Sites for Community Engagement

ERIC Educational Resources Information Center

Wells, Jaclyn Michelle

2010-01-01

This dissertation investigates the Community Writing and Education Station (CWEST), a community engagement project that partners a community adult basic literacy program with a university writing lab. The author argues that the community and university partners, the Lafayette Adult Resource Academy (LARA) and the Purdue Writing Lab, offer positive…

Maniac Talk - Dr. William Lau

NASA Image and Video Library

2014-01-24

William Lau Maniac Lecture, 24 January, 2014 Dr. William Lau, Deputy Director for Atmospheres, Earth Science Division at NASA Goddard, presented a Maniac Talk entitled "My Story: A Tale of Three Continents." Bill shared his early childhood under a colonial education system with strong Chinese cultural influence and how world events, cultural and education system of three major continents, Europe, Asia and North America shaped his upbringing career goals and work ethics.

Berkeley Lab's Saul Perlmutter wins Nobel Prize in Physics | Berkeley Lab

Science.gov Websites

astrophysics, dark energy, physics Connect twitter instagram LinkedIn facebook youtube This form needs Berkeley Lab's Saul Perlmutter wins Nobel Prize in Physics News Release Paul Preuss 510-486-6249 * October professor of physics at the University of California at Berkeley, has won the 2011 Nobel Prize in Physics

Modeling Dr. Dynasaur 2.0 Coverage and Finance Proposals

PubMed Central

Dick, Andrew W.; Price, Carter C.; Woods, Dulani; Freund, Deborah Anne; McNamara, Martin; Schramm, Steven P.; Berkman, Elrycc; Dehner, Tom

2017-01-01

Abstract The authors assessed an expansion of Vermont's Dr. Dynasaur program that would cover all residents age 25 and younger. The current Dr. Dynasaur program combines Vermont's Medicaid program and Child Health Insurance Program for children ages 0 through 18 to provide a seamless insurance program for those with family incomes below 317 percent of the federal poverty level. The authors used RAND's COMPARE-VT microsimulation model with Vermont-specific demographic, economic, and actuarial data to estimate the effects on health insurance coverage, costs, and premiums. They also identified the new revenues required to fund the program expansion and explored three alternative financing strategies to raise those funds: (1) an increase in the Vermont income tax, (2) a Vermont payroll tax, and (3) a Vermont business enterprise tax. The authors found that enrollment would increase by more than 260 percent under the 100-percent enrollment scenario and by nearly 200 percent under the 70-percent enrollment scenario by 2019. Not surprisingly, the children and young adults who move off employer-sponsored insurance (ESI) and into Dr. Dynasaur 2.0 have considerably lower expected health care costs than those who remain on ESI, increasing the per-person premiums by nearly $1,000 for those remaining enrolled in ESI. Annual health care expenditures per person for children and young adults in 2019 are estimated at $4,325 with Medicare prices. The combination of increased reimbursement rates, large increases in enrollment, and relatively low Dr. Dynasaur premiums (no more than $720 per year) will require significant new tax revenues to meet program obligations. PMID:29057152

Collected Papers in Structural Mechanics Honoring Dr. James H. Starnes, Jr.

NASA Technical Reports Server (NTRS)

Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler); Malone, John B. (Compiler)

2006-01-01

This special publication contains a collection of structural mechanics papers honoring Dr. James H. Starnes, Jr. presented at the 46th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Austin, Texas, April 18-21, 2005. Contributors to this publication represent a small number of those influenced by Dr. Starnes' technical leadership, his technical prowess and diversity, and his technical breath and depth in engineering mechanics. These papers cover some of the research areas Dr. Starnes investigated, which included buckling, postbuckling, and collapse of structures; composite structural mechanics, residual strength and damage tolerance of metallic and composite structures; and aircraft structural design, certification and verification. He actively pursued technical understanding and clarity, championed technical excellence, and modeled humility and perseverance.

The USDA Forest Service National Seed Laboratory

Treesearch

Robert P. Karrfalt

2006-01-01

The USDA Forest Service National Seed Laboratory has provided seed technology services to the forest and conservation seed and nursery industry for more than 50 years. This paper briefly traces the lab’s evolution from a regional facility concerned principally with southern pines to its newest mission as a national facility working with all native U.S. plants and...

Syndromes drépanocytaires majeurs et infections associées chez l ’enfant au Burkina Faso

PubMed Central

Douamba, Sonia; Nagalo, Kisito; Tamini, Laure; Traoré, Ismaël; Kam, Madibèlè; Kouéta, Fla; Yé, Diarra

2017-01-01

Introduction Le but de cette étude était d’étudier les infections chez les enfants présentant un syndrome drépanocytaire majeur. Méthodes Étude hospitalière monocentrique, rétrospective descriptive sur dix années menée à Ouagadougou, Burkina Faso. Étaient inclus tous les enfants porteurs d'un syndrome drépanocytaire majeur (homozygote SS et double hétérozygote SC, SDPunjab, Sβ thalassémique, SOArab et SE) hospitalisés pour une infection bactérienne confirmée à la microbiologie. Résultats Cent trente trois patients répondaient à nos critères d’inclusion. Le phénotype SS représentait 63,2% des cas et le SC 36,8%. La fréquence des infections était de 21,8%. Celles-ci touchaient dans 45,9% des cas les enfants âgés de 0 à 5 ans. Les signes les plus fréquents étaient les douleurs ostéoarticulaires (42,1%), la toux (25,7%), les douleurs abdominales (23,3%), la pâleur (43,6%). Les broncho-pneumopathies (31,6%), le paludisme (16,5%), les ostéomyélites (12,8%) et les septicémies (10,5%) étaient les principaux diagnostics trouvés. Les agents pathogènes isolés étaient Streptococcus pneumoniae (35,5%) et Salmonella sp (33,3%). Les céphalosporines de 3e génération étaient les antibiotiques les plus fréquemment prescrits. Le taux brut de mortalité était de 7,5%. Conclusion Les infections bactériennes et le paludisme dominent le tableau des infections chez l'enfant drépanocytaire majeur au Centre Hospitalier Universitaire Pédiatrique Charles De Gaulle. Les auteurs recommandent la mise en place d’un programme national de prise en charge de la drépanocytose, ce qui permettrait de prévenir voire réduire la survenue des infections chez les enfants drépanocytaires. PMID:28450986

The leadership principles of Dr. Martin Luther King, Jr. and their relevance to surgery.

PubMed

Brunicardi, F Charles; Cotton, Ronald T; Cole, George W; Martinez, George

2007-01-01

In order to face the challenges in healthcare this century, it is essential that surgeons understand modern leadership principles. One of the greatest leaders in history was Dr. Martin Luther King, Jr., who provides a shining example of level-5 leadership for us to study. The study of leadership principles of great leaders can provide us with practical methods of conflict resolution as well as inspiration to keep us engaged and focused. As leaders of the medical community, we face numerous challenges, including discovering and implementing new treatments for disease, providing care for the indigent, overcoming educational challenges such as incorporating the ACGME Core Competencies into our surgical training and promoting diversity in education. Achieving these goals is often hindered by the environment in which we labor-nearly 50 million are uninsured, the rising cost of medical care is currently at 16% of the GNP, and reimbursement rates are falling-which makes the practice of surgery a significant challenge. Effective leadership will be paramount in achieving these goals. In this editorial, which summarizes a presentation given to the Surgical Section of the annual National Medical Association meeting, five important leadership principles that are important for surgeons have been selected and related to the outstanding leadership of Dr. Martin Luther King, Jr.

ERLN Technical Support for Labs

EPA Pesticide Factsheets

The Environmental Response Laboratory Network provides policies and guidance on lab and data requirements, Standardized Analytical Methods, and technical support for water and radiological sampling and analysis

NBIC: National Ballast Information Clearinghouse

Science.gov Websites

SERC >| Marine Invasions Research Lab NBIC logo National Ballast Information Clearinghouse Smithsonian Environmental Research Center Logo US Coast Guard Logo Submit BW Report | Search NBIC Database | NBIC Research & Development | NBIC News | Home Photos of ships Photos of ships NOTE: 4 March 2018

GeneLab: A Systems Biology Platform for Spaceflight Omics Data

NASA Technical Reports Server (NTRS)

Reinsch, Sigrid S.; Lai, San-Huei; Chen, Rick; Thompson, Terri; Berrios, Daniel; Fogle, Homer; Marcu, Oana; Timucin, Linda; Chakravarty, Kaushik; Coughlan, Joseph

2015-01-01

NASA's mission includes expanding our understanding of biological systems to improve life on Earth and to enable long-duration human exploration of space. Resources to support large numbers of spaceflight investigations are limited. NASA's GeneLab project is maximizing the science output from these experiments by: (1) developing a unique public bioinformatics database that includes space bioscience relevant "omics" data (genomics, transcriptomics, proteomics, and metabolomics) and experimental metadata; (2) partnering with NASA-funded flight experiments through bio-sample sharing or sample augmentation to expedite omics data input to the GeneLab database; and (3) developing community-driven reference flight experiments. The first database, GeneLab Data System Version 1.0, went online in April 2015. V1.0 contains numerous flight datasets and has search and download capabilities. Version 2.0 will be released in 2016 and will link to analytic tools. In 2015 Genelab partnered with two Biological Research in Canisters experiments (BBRIC-19 and BRIC-20) which examine responses of Arabidopsis thaliana to spaceflight. GeneLab also partnered with Rodent Research-1 (RR1), the maiden flight to test the newly developed rodent habitat. GeneLab developed protocols for maxiumum yield of RNA, DNA and protein from precious RR-1 tissues harvested and preserved during the SpaceX-4 mission, as well as from tissues from mice that were frozen intact during spaceflight and later dissected. GeneLab is establishing partnerships with at least three planned flights for 2016. Organism-specific nationwide Science Definition Teams (SDTs) will define future GeneLab dedicated missions and ensure the broader scientific impact of the GeneLab missions. GeneLab ensures prompt release and open access to all high-throughput omics data from spaceflight and ground-based simulations of microgravity and radiation. Overall, GeneLab will facilitate the generation and query of parallel multi-omics data, and