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Sample records for national reference laboratories

  1. [The National Reference Centres and Reference Laboratories. Importance and tasks].

    PubMed

    Laude, G; Ammon, A

    2005-09-01

    Since 1995, the German Federal Ministry for Health and Social Security funds National Reference Centres (NRC) for the laboratory surveillance of important pathogens and syndromes. Which pathogens or syndromes are selected to be covered by a NRC depends on their epidemiological relevance, the special diagnostic tools, problems with antimicrobial resistance and necessary infection control measures. Currently, there are 15 NRC, which are appointed for a period of 3 years (currently from January 2005 through December 2007). Towards the end of their appointment all NRC are evaluated by a group of specialists. The assessment of their achievements is guided by a catalogue of tasks for the NRC. In addition to the NRC, a total of 50 laboratories are appointed which provide specialist expertise for additional pathogens in order to have a broad range of pathogens for which specialist laboratories are available. Their predominant task is to give advice and support for special diagnostic problems. Both NRC and the specialist laboratories are important parts of the network for infectious disease epidemiology.

  2. [On the way to national reference system of laboratory medicine].

    PubMed

    Muravskaia, N P; Men'shikov, V V

    2014-10-01

    The application of standard samples and reference techniques of implementation of measurements is needed for a valid support of reliability of analyses applied in clinical diagnostic laboratories. They play role of landmarks under metrologic monitoring, calibration of devices and control of quality of results. The article presents analysis of shortcomings interfering with formation of national reference system in Russia harmonized with possibilities provided by international organizations. Among them are the joint Committee on metrologic monitoring in laboratory medicine under the auspices of the International Bureau of Weights and Measures, the International Federation of clinical chemistry and laboratory medicine, etc. The results of the recent development of national normative documents, standard samples and techniques assisted by the authors of article are considered. They are the first steps to organization of national reference system which would comprise all range of modern analytical technologies of laboratory medicine. The national and international measures are proposed to enhance the promptest resolving of task of organization of national reference system for laboratory medicine in the interests of increasing of effectiveness of medical care to citizen of Russia.

  3. Lawrence Livermore National Laboratory Working Reference Material Production Pla

    SciTech Connect

    Wong, Amy; Thronas, Denise; Marshall, Robert

    1998-11-04

    This Lawrence Livermore National Laboratory (LLNL) Working Reference Material Production Plan was written for LLNL by the Los Alamos National Laboratory to address key elements of producing seven Pu-diatomaceous earth NDA Working Reference Materials (WRMS). These WRMS contain low burnup Pu ranging in mass from 0.1 grams to 68 grams. The composite Pu mass of the seven WRMS was designed to approximate the maximum TRU allowable loading of 200 grams Pu. This document serves two purposes: first, it defines all the operations required to meet the LLNL Statement of Work quality objectives, and second, it provides a record of the production and certification of the WRMS. Guidance provided in ASTM Standard Guide C1128-89 was used to ensure that this Plan addressed all the required elements for producing and certifying Working Reference Materials. The Production Plan was written to provide a general description of the processes, steps, files, quality control, and certification measures that were taken to produce the WRMS. The Plan identifies the files where detailed procedures, data, quality control, and certification documentation and forms are retained. The Production Plan is organized into three parts: a) an initial section describing the preparation and characterization of the Pu02 and diatomaceous earth materials, b) middle sections describing the loading, encapsulation, and measurement on the encapsulated WRMS, and c) final sections describing the calculations of the Pu, Am, and alpha activity for the WRMS and the uncertainties associated with these quantities.

  4. Annual report of the Australian National Enterovirus Reference Laboratory 2012.

    PubMed

    Roberts, Jason; Hobday, Linda; Ibrahim, Aishah; Aitken, Thomas; Thorley, Bruce

    2013-06-30

    In 2012 no cases of poliomyelitis were reported through clinical surveillance in Australia, and poliovirus was not detected through virological surveillance. Australia conducts surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years as the main mechanism to monitor its polio-free status in accordance with World Health Organization (WHO) recommendations. Cases of AFP in children are notified to the Australian Paediatric Surveillance Unit or the Paediatric Active Enhanced Disease Surveillance System. In 2012 Australia reported 1.2 non-polio AFP cases per 100,000 children, meeting the WHO performance criterion for a sensitive system for the fifth year in a row. However the faecal specimen collection rate from AFP cases was 29%, which was well below the WHO target of 80%. Virological surveillance for poliovirus consists of two components. Firstly, the Enterovirus Reference Laboratory Network of Australia (ERLNA) reports on the typing of enteroviruses detected in or isolated from clinical specimens. Secondly, environmental surveillance is conducted at sentinel sites. These surveillance systems are co-ordinated by the National Enterovirus Reference Laboratory (NERL).

  5. Australian National Enterovirus Reference Laboratory annual report, 2013.

    PubMed

    Roberts, Jason A; Hobday, Linda K; Ibrahim, Aishah; Aitkin, Thomas; Thorley, Bruce R

    2015-06-30

    Australia conducts surveillance for cases of acute flaccid paralysis (AFP) in children less than 15 years of age as the main method to monitor its polio-free status in accordance with the World Health Organization (WHO) recommendations. Cases of AFP in children are notified to the Australian Paediatric Surveillance Unit or the Paediatric Active Enhanced Disease Surveillance System and faecal specimens are referred for virological investigation to the National Enterovirus Reference Laboratory. In 2013, no cases of poliomyelitis were reported from clinical surveillance and Australia reported 1.4 non-polio AFP cases per 100,000 children, meeting the WHO performance criterion for a sensitive surveillance system. Non-polio enteroviruses can also be associated with AFP and enterovirus A71 was identified from nine of the 61 cases classified as non-polio AFP in 2013, which was part of a larger outbreak associated with this virus. A Sabin poliovirus was detected in an infant recently returned from Pakistan and who had been vaccinated while abroad. Globally, 416 cases of polio were reported in 2013, with the 3 endemic countries: Afghanistan; Nigeria; and Pakistan, accounting for 38% of the cases. To safeguard the progress made towards polio eradication, in May 2014, WHO recommended travellers from the 10 countries that are currently reporting wild poliovirus transmission have documented evidence of recent polio vaccination before departure.

  6. Annual report of the Australian National Poliovirus Reference Laboratory, 2008.

    PubMed

    Roberts, Jason A; Grant, Kristina A; Yoon, Yeon Kyung; Polychronopoulos, Sophie; Ibrahim, Aishah; Thorley, Bruce R

    2009-09-01

    The Australian National Poliovirus Reference Laboratory (NPRL) is accredited by the World Health Organization (WHO) for the testing of stool specimens from cases of acute flaccid paralysis (AFP), a major clinical presentation of poliovirus infection. The NPRL, in collaboration with the Australian Paediatric Surveillance Unit, co-ordinates surveillance for cases of AFP in children in Australia, according to criteria recommended by the WHO. Clinical specimens are referred from AFP cases in children and suspected case of poliomyelitis in persons of any age. The WHO AFP surveillance performance indicator for a polio-free country such as Australia, is 1 non-polio AFP case per 100,000 children less than 15 years of age. In 2008, the Polio Expert Committee (PEC) classified 62 cases as non-polio AFP, or 1.51 non-polio AFP cases per 100,000 children aged less than 15 years. Poliovirus infection is confirmed by virus culture of stool specimens from AFP cases as other conditions that present with acute paralysis can mimic polio. While no poliovirus was reported in Australia from any source in 2008, the non-polio enteroviruses echovirus 25, coxsackievirus B2 and echovirus 11 were isolated from stool specimens of AFP cases. The last report of a wild poliovirus in Australia was due to an importation from Pakistan in 2007. With 4 countries remaining endemic for poliomyelitis--Afghanistan, India, Nigeria and Pakistan--and more than 1,600 confirmed cases of wild poliovirus infection in 18 countries in 2008, Australia continues to be at risk of further importation events.

  7. The added value of a European Union tuberculosis reference laboratory network--analysis of the national reference laboratory activities.

    PubMed

    Drobniewski, F A; Nikolayevskyy, V; Hoffner, S; Pogoryelova, O; Manissero, D; Ozin, A J

    2008-03-18

    National reference laboratories (NRL) and other laboratories are the cornerstones of well-functioning tuberculosis programmes and surveillance activities. However, the scope and activity of NRL services for mycobacterial identification and drug susceptibility testing (DST) has not been examined in detail across the European Union (EU), nor has the added value of cooperation and networking at the European level been explored with regard to strengthening laboratory services. Therefore, the European Centre for Disease Prevention and Control (ECDC) has commissioned a survey to explore these issues and to identify areas of work that could bring added value by supporting networking activities of tuberculosis (TB) reference laboratories in the EU. Structured questionnaires were sent to TB reference laboratory experts in the EU and European Economic Area (EEA) countries, and in three additional countries selected on the basis of their networking activities with EU projects and other initiatives (Switzerland, Croatia and Israel). The compiled results describe the activities and structure of 32 NRLs (29 countries replied, a response rate of 91%). The analysis of the survey led to the following recommendations for strengthening TB laboratory services: (1) implementing of the published European standards for TB laboratory services with respect to infrastructure, national reference functions, biosafety, human resources, quality assurance, operational research (including evaluation of new medical diagnostics), accuracy and speed, appropriately trained staff; (2) ensuring that laboratories only perform activities for which they have demonstrated proficiency; (3) implement validated and standardised second-line drug susceptibility testing (DST), including drugs used to define extensively drug-resistant tuberculosis (XDR TB); (4) aiming to identify Mycobacterium tuberculosis complex (MTBC) and rifampicin (RIF) resistance in over 90% of cultures and cases from smear-positive sputum

  8. Establishment of Traceability of Reference Grade Hydrometers at National Physical Laboratory, India (npli)

    NASA Astrophysics Data System (ADS)

    Kumar, Anil; Kumar, Harish; Mandal, Goutam; Das, M. B.; Sharma, D. C.

    The present paper discusses the establishment of traceability of reference grade hydrometers at National Physical Laboratory, India (NPLI). The reference grade hydrometers are calibrated and traceable to the primary solid density standard. The calibration has been done according to standard procedure based on Cuckow's Method and the reference grade hydrometers calibrated covers a wide range. The uncertainty of the reference grade hydrometers has been computed and corrections are also calculated for the scale readings, at which observations are taken.

  9. Public health microbiology in Germany: 20 years of national reference centers and consultant laboratories.

    PubMed

    Beermann, Sandra; Allerberger, Franz; Wirtz, Angela; Burger, Reinhard; Hamouda, Osamah

    2015-10-01

    In 1995, in agreement with the German Federal Ministry of Health, the Robert Koch Institute established a public health microbiology system consisting of national reference centers (NRCs) and consultant laboratories (CLs). The goal was to improve the efficiency of infection protection by advising the authorities on possible measures and to supplement infectious disease surveillance by monitoring selected pathogens that have high public health relevance. Currently, there are 19 NRCs and 40 CLs, each appointed for three years. In 2009, an additional system of national networks of NRCs and CLs was set up in order to enhance effectiveness and cooperation within the national reference laboratory system. The aim of these networks was to advance exchange in diagnostic methods and prevention concepts among reference laboratories and to develop geographic coverage of services. In the last two decades, the German public health laboratory reference system coped with all major infectious disease challenges. The European Union and the European Centre for Disease Prevention and Control (ECDC) are considering implementing a European public health microbiology reference laboratory system. The German reference laboratory system should be well prepared to participate actively in this upcoming endeavor.

  10. Implementation of a national reference laboratory for Buruli ulcer disease in Togo.

    PubMed

    Beissner, Marcus; Huber, Kristina Lydia; Badziklou, Kossi; Halatoko, Wemboo Afiwa; Maman, Issaka; Vogel, Felix; Bidjada, Bawimodom; Awoussi, Koffi Somenou; Piten, Ebekalisai; Helfrich, Kerstin; Mengele, Carolin; Nitschke, Jörg; Amekuse, Komi; Wiedemann, Franz Xaver; Diefenhardt, Adolf; Kobara, Basile; Herbinger, Karl-Heinz; Kere, Abiba Banla; Prince-David, Mireille; Löscher, Thomas; Bretzel, Gisela

    2013-01-01

    In a previous study PCR analysis of clinical samples from suspected cases of Buruli ulcer disease (BUD) from Togo and external quality assurance (EQA) for local microscopy were conducted at an external reference laboratory in Germany. The relatively poor performance of local microscopy as well as effort and time associated with shipment of PCR samples necessitated the implementation of stringent EQA measures and availability of local laboratory capacity. This study describes the approach to implementation of a national BUD reference laboratory in Togo. Large scale outreach activities accompanied by regular training programs for health care professionals were conducted in the regions "Maritime" and "Central," standard operating procedures defined all processes in participating laboratories (regional, national and external reference laboratories) as well as the interaction between laboratories and partners in the field. Microscopy was conducted at regional level and slides were subjected to EQA at national and external reference laboratories. For PCR analysis, sample pairs were collected and subjected to a dry-reagent-based IS2404-PCR (DRB-PCR) at national level and standard IS2404 PCR followed by IS2404 qPCR analysis of negative samples at the external reference laboratory. The inter-laboratory concordance rates for microscopy ranged from 89% to 94%; overall, microscopy confirmed 50% of all suspected BUD cases. The inter-laboratory concordance rate for PCR was 96% with an overall PCR case confirmation rate of 78%. Compared to a previous study, the rate of BUD patients with non-ulcerative lesions increased from 37% to 50%, the mean duration of disease before clinical diagnosis decreased significantly from 182.6 to 82.1 days among patients with ulcerative lesions, and the percentage of category III lesions decreased from 30.3% to 19.2%. High inter-laboratory concordance rates as well as case confirmation rates of 50% (microscopy), 71% (PCR at national level), and 78

  11. Implementation of a National Reference Laboratory for Buruli Ulcer Disease in Togo

    PubMed Central

    Badziklou, Kossi; Halatoko, Wemboo Afiwa; Maman, Issaka; Vogel, Felix; Bidjada, Bawimodom; Awoussi, Koffi Somenou; Piten, Ebekalisai; Helfrich, Kerstin; Mengele, Carolin; Nitschke, Jörg; Amekuse, Komi; Wiedemann, Franz Xaver; Diefenhardt, Adolf; Kobara, Basile; Herbinger, Karl–Heinz; Kere, Abiba Banla; Prince-David, Mireille; Löscher, Thomas; Bretzel, Gisela

    2013-01-01

    Background In a previous study PCR analysis of clinical samples from suspected cases of Buruli ulcer disease (BUD) from Togo and external quality assurance (EQA) for local microscopy were conducted at an external reference laboratory in Germany. The relatively poor performance of local microscopy as well as effort and time associated with shipment of PCR samples necessitated the implementation of stringent EQA measures and availability of local laboratory capacity. This study describes the approach to implementation of a national BUD reference laboratory in Togo. Methodology Large scale outreach activities accompanied by regular training programs for health care professionals were conducted in the regions “Maritime” and “Central,” standard operating procedures defined all processes in participating laboratories (regional, national and external reference laboratories) as well as the interaction between laboratories and partners in the field. Microscopy was conducted at regional level and slides were subjected to EQA at national and external reference laboratories. For PCR analysis, sample pairs were collected and subjected to a dry-reagent-based IS2404-PCR (DRB-PCR) at national level and standard IS2404 PCR followed by IS2404 qPCR analysis of negative samples at the external reference laboratory. Principal Findings The inter-laboratory concordance rates for microscopy ranged from 89% to 94%; overall, microscopy confirmed 50% of all suspected BUD cases. The inter-laboratory concordance rate for PCR was 96% with an overall PCR case confirmation rate of 78%. Compared to a previous study, the rate of BUD patients with non-ulcerative lesions increased from 37% to 50%, the mean duration of disease before clinical diagnosis decreased significantly from 182.6 to 82.1 days among patients with ulcerative lesions, and the percentage of category III lesions decreased from 30.3% to 19.2%. Conclusions High inter-laboratory concordance rates as well as case confirmation

  12. Report of the Australian National Polio Reference Laboratory. 1 July to 31 December 1999.

    PubMed

    Kennett, M; Stambos, V; Turnbull, A; Ibrahim, A; Kelly, H

    2000-05-01

    Since 1994, as part of the global eradication of poliomyelitis, the Australian National Polio Reference Laboratory (NPRL) at the Victorian Infectious Diseases Reference Laboratory (VIDRL) has been responsible for virological testing to confirm the absence of poliomyelitis in Australia. Samples from patients with acute flaccid paralysis are transported to VIDRL for viral culture. Polio and enteroviruses are referred for intratypic differentiation as wild or Sabin (vaccine) strains. A total of 23 faecal specimens from 17 patients were processed for enterovirus culture in the period 1 July to 31 December 1999. Since 1995, 1,078 enterovirus isolates from six states have been tested for the presence of wild poliovirus. To date, 562 strains were confirmed as Sabin vaccine-like, one non Sabin-like strain was identical with a laboratory control virus and the other strains were non-polio enteroviruses or other viruses. A World Health Organization (WHO) workshop in diagnostic polio polymerase chain reaction techniques was held at VIDRL in November 1999. The laboratory was reaccredited as a regional polio reference laboratory for the WHO Western Pacific region and a national laboratory for Australia, the Pacific Island countries and Brunei Darussalam. Planning is proceeding for the polio-free certification and containment of laboratory stocks of wild poliovirus infectious materials in Australia.

  13. Mozambique’s journey toward accreditation of the National Tuberculosis Reference Laboratory

    PubMed Central

    Madeira, Carla; Aguiar, Carmen; Dolores, Carolina; Mandlaze, Ana P.; Chongo, Patrina; Masamha, Jessina

    2017-01-01

    Background Internationally-accredited laboratories are recognised for their superior test reliability, operational performance, quality management and competence. In a bid to meet international quality standards, the Mozambique National Institute of Health enrolled the National Tuberculosis Reference Laboratory (NTRL) in a continuous quality improvement process towards ISO 15189 accreditation. Here, we describe the road map taken by the NTRL to achieve international accreditation. Methods The NTRL adopted the Strengthening Laboratory Management Toward Accreditation (SLMTA) programme as a strategy to implement a quality management system. After SLMTA, the Mozambique National Institute of Health committed to accelerate the NTRL’s process toward accreditation. An action plan was designed to streamline the process. Quality indicators were defined to benchmark progress. Staff were trained to improve performance. Mentorship from an experienced assessor was provided. Fulfilment of accreditation standards was assessed by the Portuguese Accreditation Board. Results Of the eight laboratories participating in SLMTA, the NTRL was the best-performing laboratory, achieving a 53.6% improvement over the SLMTA baseline conducted in February 2011 to the Stepwise Laboratory Quality Improvement Process Towards Accreditation (SLIPTA) assessment in June 2013. During the accreditation assessment in September 2014, 25 minor nonconformities were identified and addressed. In March 2015, the NTRL received Portuguese Accreditation Board recognition of technical competency for fluorescence smear microscopy, and solid and liquid culture. The NTRL is the first laboratory in Mozambique to achieve ISO 15189 accreditation. Conclusions From our experience, accreditation was made possible by institutional commitment, strong laboratory leadership, staff motivation, adequate infrastructure and a comprehensive action plan. PMID:28879162

  14. Annual report of the Australian National Enterovirus Reference Laboratory 2010-2011.

    PubMed

    Roberts, Jason; Hobday, Linda; Ibrahim, Aishah; Aitken, Thomas; Thorley, Bruce

    2013-06-30

    Australia conducts clinical surveillance for cases of polio-like illness in children in accordance with the World Health Organization (WHO) recommended surveillance criteria for acute flaccid paralysis (AFP). AFP cases are ascertained either by clinicians notifying the Australian Paediatric Surveillance Unit or designated nurses enrolling cases as part of the Paediatric Active Enhanced Disease Surveillance system at four sentinel tertiary paediatric hospitals. The National Enterovirus Reference Laboratory (NERL), formerly the National Poliovirus Reference Laboratory, is accredited by the World Health Organization (WHO) for the testing of faecal specimens from cases of AFP and operates as a Poliovirus Regional Reference Laboratory for the Western Pacific Region. In 2010 and 2011, for the 3rd and 4th consecutive years, Australia met the WHO AFP surveillance performance indicator. This is indicative of a sensitive surveillance system capable of detecting an imported case of polio in children. However, the faecal collection rate for the virological investigation of AFP cases was below the WHO surveillance performance indicator in both years and represented a gap in Australia's polio surveillance. Enterovirus and environmental surveillance were established in Australia as virological surveillance to complement the clinical surveillance schemes. No poliovirus was detected by the clinical or virological surveillance schemes in 2010 or 2011 and Australia maintained its polio-free status. India was declared polio-free in January 2012, a significant step towards global polio eradication, leaving Afghanistan, Nigeria and Pakistan as the remaining countries endemic for wild poliovirus.

  15. Reference site selection report for the advanced liquid metal reactor at the Idaho National Engineering Laboratory

    SciTech Connect

    Sivill, R.L.

    1990-03-01

    This Reference Site Selection Report was prepared by EG G, Idaho Inc., for General Electric (GE) to provide information for use by the Department of Energy (DOE) in selecting a Safety Test Site for an Advanced Liquid Metal Reactor. Similar Evaluation studies are planned to be conducted at other potential DOE sites. The Power Reactor Innovative Small Module (PRISM) Concept was developed for ALMR by GE. A ALMR Safety Test is planned to be performed on a DOE site to demonstrate features and meet Nuclear Regulatory Commission Requirements. This study considered possible locations at the Idaho National Engineering Laboratory that met the ALMR Prototype Site Selection Methodology and Criteria. Four sites were identified, after further evaluation one site was eliminated. Each of the remaining three sites satisfied the criteria and was graded. The results were relatively close. Thus concluding that the Idaho National Engineering Laboratory is a suitable location for an Advanced Liquid Metal Reactor Safety Test. 23 refs., 13 figs., 9 tabs.

  16. [Capability of national reference laboratories in Latin America to detect emerging resistance mechanisms].

    PubMed

    Corso, Alejandra; Guerriero, Leonor; Pasterán, Fernando; Ceriana, Paola; Callejo, Raquel; Prieto, Mónica; Tuduri, Ezequiel; Lopardo, Horacio; Vay, Carlos; Smayevsky, Jorgelina; Tokumoto, Marta; Alvarez, Jorge Matheu; Pardo, Pilar Ramón; Galas, Marcelo

    2011-12-01

    To evaluate the capability of 17 national reference laboratories participating in the Latin American Quality Control Program in Bacteriology and Antibiotic Resistance (LA-EQAS) to detect emerging resistance mechanisms- namely: resistance of enterobacteria to carbapenems due to the presence of Klebsiella pneumoniae carbapenemase (KPC) and metallo-beta-lactamase (MBL) type IMP, and intermediate resistance of Staphylococcus aureus isolates to vancomycin (vancomycin-intermediate resistant S. aureus-VISA). The following three isolates were sent to the 17 participating LA-EQAS laboratories: KPC -producing Klebsiella pneumoniae PAHO-161, IMP-producing Enterobacter cloacae PAHO-166, and S. aureus PAHO-165 with intermediate resistance to vancomycin. Performance of each of the following operations was evaluated: interpretation of sensitivity tests, detection of the resistance mechanism, and assessment of either inhibition halo size (disk diffusion method) or minimum inhibitory concentration (MIC). Concordance in the detection of resistance mechanisms was 76.4%, 73.3%, and 66.7% for the K. pneumoniae PAHO-161, E. cloacae PAHO-166, and S. aureus PAHO-165 strains, respectively. Concordance between the inhibition areas observed by the participating laboratories and the ranges established by the coordinating laboratory was acceptable for all three isolates, at 90.8%, 92.8%, and 88.9%, respectively. Overall concordance in on the detection of KPC, MBL, and VISA resistance mechanisms was 72.1%. We consider the national reference laboratories in Latin America capable of recognizing these emerging resistance mechanisms and expect that maximum levels of concordance will be reached in the future.

  17. [Establishment of Networks of National Reference Centres and associated Consiliary Laboratories in Germany].

    PubMed

    Laude, G; Kist, M; Krause, G

    2009-10-01

    The German Federal Ministry of Health has funded National Reference Centres (NRC) for laboratory-based surveillance of selected infection pathogens and infections disease syndromes. This selection is based on the epidemiologic relevance of the pathogens, specific diagnostic requirements, antimicrobial resistance and need for public health measures. Currently there are 18 NRC, nominated for a duration of 3 years. Toward the end of a nomination period, each NRC is evaluated by an expert committee, based on the catalogue of core tasks. In order to expand the spectrum of competencies 47 consiliary laboratories on additional pathogens of special epidemiologic importance have been named. Their main function is to provide information and consultation on special diagnostic issues. In order to further improve the effectiveness and cooperation of the system Networks have been created. The aim of the Networks is to facilitate exchange of diagnostic methods and prevention concepts and to improve the geographic coverage of the services.

  18. National Survey of Adult and Pediatric Reference Intervals in Clinical Laboratories across Canada: A Report of the CSCC Working Group on Reference Interval Harmonization.

    PubMed

    Adeli, Khosrow; Higgins, Victoria; Seccombe, David; Collier, Christine P; Balion, Cynthia M; Cembrowski, George; Venner, Allison A; Shaw, Julie

    2017-06-21

    Reference intervals are widely used decision-making tools in laboratory medicine, serving as health-associated standards to interpret laboratory test results. Numerous studies have shown wide variation in reference intervals, even between laboratories using assays from the same manufacturer. Lack of consistency in either sample measurement or reference intervals across laboratories challenges the expectation of standardized patient care regardless of testing location. Here, we present data from a national survey conducted by the Canadian Society of Clinical Chemists (CSCC) Reference Interval Harmonization (hRI) Working Group that examines variation in laboratory reference sample measurements, as well as pediatric and adult reference intervals currently used in clinical practice across Canada. Data on reference intervals currently used by 37 laboratories were collected through a national survey to examine the variation in reference intervals for seven common laboratory tests. Additionally, 40 clinical laboratories participated in a baseline assessment by measuring six analytes in a reference sample. Of the seven analytes examined, alanine aminotransferase (ALT), alkaline phosphatase (ALP), and creatinine reference intervals were most variable. As expected, reference interval variation was more substantial in the pediatric population and varied between laboratories using the same instrumentation. Reference sample results differed between laboratories, particularly for ALT and free thyroxine (FT4). Reference interval variation was greater than test result variation for the majority of analytes. It is evident that there is a critical lack of harmonization in laboratory reference intervals, particularly for the pediatric population. Furthermore, the observed variation in reference intervals across instruments cannot be explained by the bias between the results obtained on instruments by different manufacturers. Copyright © 2017 The Canadian Society of Clinical Chemists

  19. Groove depth measurements on roughness reference standards of the Croatian National Laboratory for Length (LFSB)

    NASA Astrophysics Data System (ADS)

    Baršić, Gorana; Mahović, Sanjin; Bartolo Picotto, Gian; Amer, Mohamed A.; Runje, Biserka

    2011-09-01

    In the Laboratory for Precise Measurements of Length, LFSB, which is now the Croatian National Laboratory for Length, unique roughness reference standards were developed in the year 1986. Because of the world-class quality of those standards and their measuring features, the same were sold in several European countries, and today they, among others, are used as roughness reference standards in Italy, Slovenia and Croatia. However, especially in the last decade, there was significant progress in the field of nanotechnology that led to the development of new measuring equipment. The above-mentioned standards due to their size, production technology and measuring features cannot fully meet metrological requirements in the field of nanometrology, i.e. they are not compatible with scanning probe microscopes. Therefore, it was decided to search for possible limitations in the procedure of groove depth measurements on the LFSB standards. In order to include as many measuring devices as possible, i.e. measurement methods, in this research, in 2008 the LFSB launched EURAMET Project 1012 'Limitations of methods for measuring the depth of the groove' in collaboration with national metrology institutes of Italy and Egypt. In this paper the results of measurements performed within the project are presented, and based on the obtained results, the advantages and limitations of the LFSB standards have been discussed, with recommendations for their improvement.

  20. Implementation of quality management systems and progress towards accreditation of National Tuberculosis Reference Laboratories in Africa.

    PubMed

    Albert, Heidi; de Dieu Iragena, Jean; Kao, Kekeletso; Erni, Donatelle; Mekonen, Teferi; Onyebujoh, Philip C

    2017-01-01

    Laboratory services are essential at all stages of the tuberculosis care cascade, from diagnosis and drug resistance testing to monitoring response to treatment. Enabling access to quality services is a challenge in low-resource settings. Implementation of a strong quality management system (QMS) and laboratory accreditation are key to improving patient care. The study objective was to determine the status of QMS implementation and progress towards accreditation of National Tuberculosis Reference Laboratories (NTRLs) in the African Region. An online questionnaire was administered to NTRL managers in 47 World Health Organization Regional Office for Africa member states in the region, between February and April 2015, regarding the knowledge of QMS tools and progress toward implementation to inform strategies for tuberculosis diagnostic services strengthening in the region. A total of 21 laboratories (43.0%) had received SLMTA/TB-SLMTA training, of which 10 had also used the Global Laboratory Initiative accreditation tool. However, only 36.7% of NTRLs had received a laboratory audit, a first step in quality improvement. Most NTRLs participated in acid-fast bacilli microscopy external quality assurance (95.8%), although external quality assurance for other techniques was lower (60.4% for first-line drug susceptibility testing, 25.0% for second-line drug susceptibility testing, and 22.9% for molecular testing). Barriers to accreditation included lack of training and accreditation programmes. Only 28.6% of NTRLs had developed strategic plans and budgets which included accreditation. Good foundations are in place on the continent from which to scale up accreditation efforts. Laboratory audits should be conducted as a first step in developing quality improvement action plans. Political commitment and strong leadership are needed to drive accreditation efforts; advocacy will require clear evidence of patient impact and cost-benefit.

  1. [Networks of National Reference Centers and associated Consiliary Laboratories in Germany].

    PubMed

    Laude, G; Kist, M; Krause, G

    2012-02-01

    Since 1995, the Robert Koch-Institute in agreement with the Federal Ministry of Health in Germany has increased the funding of National Reference Centers (NRC) and Consiliary Laboratories (CL) for laboratory-based surveillance of selected infection pathogens and infectious disease syndromes. Their goal is to improve efficient protection from infections and to supplement infectious disease surveillance by monitoring selected pathogens. Currently there are 19 NRC and 48 CL, nominated for a duration of 3 years. In order to enhance the effectiveness and cooperation of the system, ten National Networks were launched in 2009. The aim of these networks is to facilitate exchange on diagnostic methods and prevention concepts and to improve the geographic coverage of the services. Furthermore, the networks provide an opportunity to work on issues beyond single pathogens more productively and efficiently. In addition, the inclusion of external and international specialists should to be included more often in the future. The activities of the networks are evaluated by the commission for infectious disease epidemiology. The commission develops promotion modalities to support collaboration between NRC and CL and to adapt it to more closely meet the requirements at the national and international levels.

  2. Spectral Karyotyping for identification of constitutional chromosomal abnormalities at a national reference laboratory

    PubMed Central

    2012-01-01

    Spectral karyotyping is a diagnostic tool that allows visualization of chromosomes in different colors using the FISH technology and a spectral imaging system. To assess the value of spectral karyotyping analysis for identifying constitutional supernumerary marker chromosomes or derivative chromosomes at a national reference laboratory, we reviewed the results of 179 consecutive clinical samples (31 prenatal and 148 postnatal) submitted for spectral karyotyping. Over 90% of the cases were requested to identify either small supernumerary marker chromosomes (sSMCs) or chromosomal exchange material detected by G-banded chromosome analysis. We also reviewed clinical indications of those cases with marker chromosomes in which chromosomal origin was identified by spectral karyotyping. Our results showed that spectral karyotyping identified the chromosomal origin of marker chromosomes or the source of derivative chromosomal material in 158 (88%) of the 179 clinical cases; the identification rate was slightly higher for postnatal (89%) compared to prenatal (84%) cases. Cases in which the origin could not be identified had either a small marker chromosome present at a very low level of mosaicism (< 10%), or contained very little euchromatic material. Supplemental FISH analysis confirmed the spectral karyotyping results in all 158 cases. Clinical indications for prenatal cases were mainly for marker identification after amniocentesis. For postnatal cases, the primary indications were developmental delay and multiple congenital anomalies (MCA). The most frequently encountered markers were of chromosome 15 origin for satellited chromosomes, and chromosomes 2 and 16 for non-satellited chromosomes. We were able to obtain pertinent clinical information for 47% (41/88) of cases with an identified abnormal chromosome. We conclude that spectral karyotyping is sufficiently reliable for use and provides a valuable diagnostic tool for establishing the origin of supernumerary marker

  3. A National Laboratory and University Branch Campus Library Partnership: Shared Benefits and Challenges from Combined Reference Services

    SciTech Connect

    Buxton, Karen A.; Gover, Harvey R.

    2003-12-31

    The Hanford Technical Library of the Pacific Northwest National Laboratory and the Max E. Benitz Memorial Library of the Washington State University Tri-Cities Branch Campus have functioned both separately and in combination since moving into the same space within the Consolidated Information Center in 1997. The libraries have successfully partnered to serve different clientele at a combined reference desk since June 1997. Although having separate staffs, catalogs, and collections, the libraries share a single reference/information desk. The reference staffs work together to serve a very diverse clientele including students, faculty, engineers, scientists, contractors, regulators, and the public. The combined libraries offer significant benefits to both library staffs and their users. The libraries have expanded access to collections and information expertise, enhanced staff training opportunities, and provided additional hours of reference service to patrons while at the same time maintaining the individual identities of the two libraries.

  4. Role of Sample Processing Strategies at the European Union National Reference Laboratories (NRLs) Concerning the Analysis of Pesticide Residues.

    PubMed

    Hajeb, Parvaneh; Herrmann, Susan S; Poulsen, Mette E

    2017-07-19

    The guidance document SANTE 11945/2015 recommends that cereal samples be milled to a particle size preferably smaller than 1.0 mm and that extensive heating of the samples should be avoided. The aim of the present study was therefore to investigate the differences in milling procedures, obtained particle size distributions, and the resulting pesticide residue recovery when cereal samples were milled at the European Union National Reference Laboratories (NRLs) with their routine milling procedures. A total of 23 NRLs participated in the study. The oat and rye samples milled by each NRL were sent to the European Union Reference Laboratory on Cereals and Feedingstuff (EURL) for the determination of the particle size distribution and pesticide residue recovery. The results showed that the NRLs used several different brands and types of mills. Large variations in the particle size distributions and pesticide extraction efficiencies were observed even between samples milled by the same type of mill.

  5. Proficiency testing linked to the national reference system for the clinical laboratory: a proposal for achieving accuracy.

    PubMed

    Lasky, F D

    1992-07-01

    I propose using proficiency testing (PT) to achieve one of the important goals of CLIA: accurate and reliable clinical testing. Routine methods for the clinical laboratory are traceable to Definitive (DM) or Reference Methods (RM) or to Methodological Principles (MP) through a modification of the National Reference System for the Clinical Laboratory. PT is the link used to monitor consistent field performance. Although PT has been effective as a relative measure of laboratory performance, the technical limitations of PT fluids and of routine methods currently in use make it unlikely that PT alone can be used as a reliable measure of laboratory accuracy. Instead, I recommend calibration of routine systems through correlation to DM, RM, or MP with use of patients' specimens. The manufacturer is in the best position to assume this responsibility because of also being responsible for consistent, reliable product. Analysis of different manufactured batches of reagent would be compared with predetermined goals for precision and accuracy, as illustrated with data from product testing of Kodak Ektachem clinical chemistry slides. Adoption of this proposal would give manufacturers of PT materials, manufacturers of analytical systems, PT providers, and government agencies time to understand and resolve sources of error that limit the utility of PT for the job required by law.

  6. Proficiency analysis of drug susceptibility testing by national-level tuberculosis reference laboratories from 1995 to 2003.

    PubMed

    Bai, Gill-Han; Kim, Sang-Jae; Chang, Chulhun L

    2007-11-01

    A proficiency review of antituberculous drug susceptibility testing (DST) was undertaken by the regional tuberculosis reference laboratories of the Western Pacific Region of WHO to evaluate the performance of national reference laboratories (NRLs) and to ensure that the results from the participating laboratories are reliable and similar. A panel of 30 Mycobacterium tuberculosis strains with various patterns of resistance to isoniazid, rifampin, ethambutol, and streptomycin was sent to the NRLs, and their DST results were analyzed by comparing them with the judicial results. The efficiency scores for each drug were 90 to 99% (mean, 95%) for isoniazid, 77 to 100% (mean, 94%) for rifampin, 82 to 97% (mean, 90%) for ethambutol, and 82 to 98% (mean, 89%) for streptomycin. Significant changes over time in the rates of accordance with the judicial results were observed for rifampin (P < 0.0001) and streptomycin (P = 0.0002), whereas no changes were observed for ethambutol (P = 0.0880). The efficiency score for isoniazid was consistently good throughout the nine rounds. As a whole, NRL02 showed the highest score (95%) in accordance rates for all drugs, while NRL03 (86%) and NRL04 (88%) ranked lowest. Continued proficiency testing with subsequent technical assistance improved the DST quality of participating laboratories, demonstrating the importance of the current WHO/IUATLD external quality assurance program for DST proficiency testing.

  7. External quality assessment for molecular typing of Salmonella 2013-2015: performance of the European national public health reference laboratories.

    PubMed

    Jensen, M B F; Schjørring, S; Björkman, J T; Torpdahl, M; Litrup, E; Nielsen, E M; Niskanen, T

    2017-06-01

    We report the results of three consecutive External Quality Assessments (EQAs) for molecular subtyping of Salmonella to assess the performance of the European national public health reference laboratories (NPHRLs). The EQA included the molecular typing methods used for European enhanced surveillance of human Salmonella infections: pulsed field gel electrophoresis (PFGE), including gel analysis by the use of the software BioNumerics, and 5-locus multiple locus variable number of tandem repeat analysis (MLVA) for serovar Typhimurium. The participation in the PFGE laboratory part was higher (27/35) than in the gel analysis (19/35) and MLVA (15/35), suggestive of the need for capacity building in methods requiring specialized equipment (MLVA) or software (gel analysis). The majority (25/27) of the participating NPHRLs produced inter-laboratory comparable PFGE gel(s). Two laboratories continued to produce low-quality gels and should have additional technical assistance in the future. In particular, two gel quality evaluation parameters, measuring "image acquisition and running conditions" and "bands", were identified to cause gel quality problems throughout the EQAs. Despite the high number of laboratories participating in the PFGE laboratory part, the participation in gel analysis was low, although increasing. In the MLVA part, the NPHRLs correctly assigned 96% (405/420) allelic profiles according to the nomenclature. In conclusion, the EQAs identified critical parameters for unsuccessful performance and helped to offer assistance to those laboratories that needed it most. The assessments supported the development of quality in molecular typing and promoted the harmonization of subtyping methods used for EU/EEA-wide surveillance of human Salmonella infections.

  8. Impact of the Yosemite hantavirus outbreak on hantavirus antibody testing at a national reference laboratory.

    PubMed

    Prince, Harry E; Lieberman, Jay M

    2013-08-01

    In conjunction with the 2012 Yosemite hantavirus outbreak, the number of sera our facility tested for hantavirus antibodies increased. We tracked test results and used the data set to determine if a more efficient testing algorithm was possible. Sera were screened using laboratory-developed pan-hantavirus IgG and IgM enzyme immunoassays (EIAs), with an index of >1.10 defined as positive. Sera that were IgM positive by screening (screen IgM(+)) were tested for Sin Nombre virus (SNV)-specific IgM using a laboratory-developed EIA; screen IgM(+) IgG(+) sera were also tested for SNV IgG using a laboratory-developed immunoblot assay. SNV antibody-positive samples were sent to state public health laboratories (PHL) or the CDC for confirmation. Of 3,946 sera tested from July through December 2012, 205 were screen IgM(+) IgG negative (IgG(-)); 7/205 were SNV IgM(+), but only 1/5 sent to PHL/CDC was confirmed as SNV IgM(+). Of 61 screen IgM(+) IgG(+) sera, 16 were SNV antibody positive; 13/16 sera (from 11 patients) went to PHL/CDC, where SNV infection was confirmed for all patients. Of 12 confirmed patients, 7 had been exposed at Yosemite. A modified algorithm defining screen indices of ≥2.00 as positive identified 11/12 confirmed cases while reducing the number of sera requiring SNV-specific antibody testing by 65%; the patient missed was not tested until 3 months after the onset of symptoms. Hantavirus antibody testing at our facility identified 12 SNV-infected patients, including 7 exposed at Yosemite. Some screen IgM(+) IgG(-) SNV IgM(+) results were false positives, emphasizing the value of PHL/CDC confirmatory testing. We identified a modified algorithm requiring analysis of fewer specimens for SNV-specific antibodies without loss of sensitivity.

  9. Impact of the Yosemite Hantavirus Outbreak on Hantavirus Antibody Testing at a National Reference Laboratory

    PubMed Central

    Lieberman, Jay M.

    2013-01-01

    In conjunction with the 2012 Yosemite hantavirus outbreak, the number of sera our facility tested for hantavirus antibodies increased. We tracked test results and used the data set to determine if a more efficient testing algorithm was possible. Sera were screened using laboratory-developed pan-hantavirus IgG and IgM enzyme immunoassays (EIAs), with an index of >1.10 defined as positive. Sera that were IgM positive by screening (screen IgM+) were tested for Sin Nombre virus (SNV)-specific IgM using a laboratory-developed EIA; screen IgM+ IgG+ sera were also tested for SNV IgG using a laboratory-developed immunoblot assay. SNV antibody-positive samples were sent to state public health laboratories (PHL) or the CDC for confirmation. Of 3,946 sera tested from July through December 2012, 205 were screen IgM+ IgG negative (IgG−); 7/205 were SNV IgM+, but only 1/5 sent to PHL/CDC was confirmed as SNV IgM+. Of 61 screen IgM+ IgG+ sera, 16 were SNV antibody positive; 13/16 sera (from 11 patients) went to PHL/CDC, where SNV infection was confirmed for all patients. Of 12 confirmed patients, 7 had been exposed at Yosemite. A modified algorithm defining screen indices of ≥2.00 as positive identified 11/12 confirmed cases while reducing the number of sera requiring SNV-specific antibody testing by 65%; the patient missed was not tested until 3 months after the onset of symptoms. Hantavirus antibody testing at our facility identified 12 SNV-infected patients, including 7 exposed at Yosemite. Some screen IgM+ IgG− SNV IgM+ results were false positives, emphasizing the value of PHL/CDC confirmatory testing. We identified a modified algorithm requiring analysis of fewer specimens for SNV-specific antibodies without loss of sensitivity. PMID:23740929

  10. [Influenza surveillance in nine consecutive seasons, 2003-2012: results from National Influenza Reference Laboratory, Istanbul Faculty Of Medicine, Turkey].

    PubMed

    Akçay Ciblak, Meral; Kanturvardar Tütenyurd, Melis; Asar, Serkan; Tulunoğlu, Merve; Fındıkçı, Nurcihan; Badur, Selim

    2012-10-01

    Influenza is a public health problem that affects 5-20% of the world population annually causing high morbidity and mortality especially in risk groups. In addition to determining prevention and treatment strategies with vaccines and antivirals, surveillance data plays an important role in combat against influenza. Surveillance provides valuable data on characteristics of influenza activity, on types, sub-types, antigenic properties and antiviral resistance profile of circulating viruses in a given region. The first influenza surveillance was initiated as a pilot study in 2003 by now named National Influenza Reference Laboratory, Istanbul Faculty of Medicine. Surveillance was launched at national level by Ministry of Health in 2004 and two National Influenza Laboratories, one in Istanbul and the other in Ankara, have been conducting surveillance in Turkey. Surveillance data obtained for nine consecutive years, 2003-2012, by National Influenza Reference Laboratory in Istanbul Faculty of Medicine have been summarized in this report. During 2003-2012 influenza surveillance seasons, a total of 11.077 nasal swabs collected in viral transport medium were sent to the National Influenza Reference Laboratory, Istanbul for analysis. Immun-capture ELISA followed by MDCK cell culture was used for detection of influenza viruses before 2009 and real-time RT-PCR was used thereafter. Antigenic characterizations were done by hemagglutination inhibition assay with the reactives supplied by World Health Organization. Analysis of the results showed that influenza B viruses have entered the circulation in 2005-2006 seasons, and have contributed to the epidemics at increasing rates every year except in the 2009 pandemic season. Influenza B Victoria and Yamagata lineages were cocirculating for two seasons. For other seasons either lineage was in circulation. Antigenic characterization revealed that circulating B viruses matched the vaccine composition either partially or totally for only

  11. National Software Reference Library (NSRL)

    National Institute of Standards and Technology Data Gateway

    National Software Reference Library (NSRL) (PC database for purchase)   A collaboration of the National Institute of Standards and Technology (NIST), the National Institute of Justice (NIJ), the Federal Bureau of Investigation (FBI), the Defense Computer Forensics Laboratory (DCFL),the U.S. Customs Service, software vendors, and state and local law enforement organizations, the NSRL is a tool to assist in fighting crime involving computers.

  12. Status, quality and specific needs of Zika virus (ZIKV) diagnostic capacity and capability in National Reference Laboratories for arboviruses in 30 EU/EEA countries, May 2016.

    PubMed

    Mögling, Ramona; Zeller, Hervé; Revez, Joana; Koopmans, Marion; Reusken, Chantal

    2017-09-07

    With international travel, Zika virus (ZIKV) is introduced to Europe regularly. A country's ability to robustly detect ZIKV introduction and local transmission is important to minimise the risk for a ZIKV outbreak. Therefore, sufficient expertise and diagnostic capacity and capability are required in European laboratories. To assess the capacity, quality, operational specifics (guidelines and algorithms), technical and interpretation issues and other possible difficulties that were related to ZIKV diagnostics in European countries, a questionnaire was conducted among national reference laboratories in 30 countries in the European Union/European Economic Area (EU/EEA) in May 2016. While the coverage and capacity of ZIKV diagnostics in the EU/EEA national reference laboratories were found to be adequate, the assessment of the quality and needs indicated several crucial points of improvement that will need support at national and EU/EEA level to improve ZIKV preparedness, response and EU/EEA ZIKV surveillance activities. This article is copyright of The Authors, 2017.

  13. Employment at National Laboratories

    SciTech Connect

    E. S. Peterson; C. A. Allen

    2007-04-01

    Scientists enter the National Laboratory System for many different reasons. For some, faculty positions are scarce, so they take staff-scientist position at national laboratories (i.e. Pacific Northwest, Idaho, Los Alamos, and Brookhaven). Many plan to work at the National Laboratory for 5 to 7 years and then seek an academic post. For many (these authors included), before they know it it’s 15 or 20 years later and they never seriously considered leaving the laboratory system.

  14. On National Laboratory Organization.

    ERIC Educational Resources Information Center

    Miller, James O.; And Others

    This paper discusses the problems and issues involved in the organizational structure of the National Laboratory on Early Childhood Education. The National Laboratory, which consisted of a coordination center and six university based research and development centers, was organized for the purpose of planning, sponsoring and conducting research and…

  15. Los Alamos National Laboratory.

    ERIC Educational Resources Information Center

    Hammel, Edward F., Jr.

    1982-01-01

    Current and post World War II scientific research at the Los Alamos National Laboratory (New Mexico) is discussed. The operation of the laboratory, the Los Alamos consultant program, and continuation education, and continuing education activities at the laboratory are also discussed. (JN)

  16. Los Alamos National Laboratory.

    ERIC Educational Resources Information Center

    Hammel, Edward F., Jr.

    1982-01-01

    Current and post World War II scientific research at the Los Alamos National Laboratory (New Mexico) is discussed. The operation of the laboratory, the Los Alamos consultant program, and continuation education, and continuing education activities at the laboratory are also discussed. (JN)

  17. Sandia National Laboratories

    NASA Technical Reports Server (NTRS)

    Gilliom, Laura R.

    1992-01-01

    Sandia National Laboratories has identified technology transfer to U.S. industry as a laboratory mission which complements our national security mission and as a key component of the Laboratory's future. A number of technology transfer mechanisms - such as CRADA's, licenses, work-for-others, and consortia - are identified and specific examples are given. Sandia's experience with the Specialty Metals Processing Consortium is highlighted with a focus on the elements which have made it successful. A brief discussion of Sandia's potential interactions with NASA under the Space Exploration Initiative was included as an example of laboratory-to-NASA technology transfer. Viewgraphs are provided.

  18. [Clinical, radiological and laboratory features of liver hydatidosis of patients from a hospital of national reference, Lima 1997-2010].

    PubMed

    Montúfar-Valer, Augudberto; Huapaya-Jurado, Francisco L

    2014-07-01

    To describe the clinical, laboratory and radiological features of patients with hepatic hydatid cyst treated at the department of general surgery of a national referral hospital in Lima (Peru). A cross-sectional study was performed, all patients diagnosed with hepatic hydatid cyst hospitalized between 1997 and 2010 were included. Sociodemographic data (age, sex, origin and usual activity), clinical, laboratory, radiographic and data referrals to treatment were collected. The most common symptom was abdominal pain (93.9%), while the most frequent sign was the increase in liver span (68.7%). 86.4% of patients had a leukocyte formulated within normal ranges, eosinophilia was only present in 25.9% of cases. The right hepatic lobe was the most affected (80%) and in 40.8% of patient's condition one segment was found. In 75.4% of patients the cysts were unique. The most frequent complications were: communication to the bile duct (48.9%), hydatid abscesses (32.6%), cholangitis (4%), hydatid cyst and broken more peritonitis (4%). The population more affected was young adults aged 30 to 39 years. The population studied lives mostly in the department of Lima, but come from departments where hepatic hydatid disease has been described as endemic. Although this population is mostly urban, epidemiological characteristics do not vary in relation to that described in previous research.

  19. National Exposure Research Laboratory

    EPA Pesticide Factsheets

    The Ecosystems Research Division of EPA’s National Exposure Research Laboratory, conducts research on organic and inorganic chemicals, greenhouse gas biogeochemical cycles, and land use perturbations that create stressor exposures and potentia risk

  20. Requirements for Reference (Calibration) Laboratories in Laboratory Medicine

    PubMed Central

    Siekmann, Lothar

    2007-01-01

    In addition to reference measurement procedures and reference materials, reference or calibration laboratories play an integral role in the implementation of measurement traceability in routine laboratories. They provide results of measurements using higher-order methods, e.g. isotope dilution mass spectrometry and may assign values to materials to be used for external quality assessment programs and to secondary reference materials. The requirements for listing of laboratories that provide reference measurement services include a statement of the metrological level or principle of measurement, accreditation as a calibration laboratory according to ISO 15195 and the participation in a proficiency testing system (regular inter-laboratory comparisons) for reference laboratories. Ring trials are currently conducted for thirty well-defined measurands and the results are made available to all laboratories. Through the use of reference laboratory services that are listed by the Joint Committee for Traceability in Laboratory Medicine there is the opportunity to further promote traceability and standardisation of laboratory measurements. PMID:18392129

  1. Trace Elements, With Special Reference to Mercury, in Fish Collected Upstream and Downstream of Los Alamos National Laboratory

    SciTech Connect

    P. R. Fresquez; J. D. Huchton; M. A. Mullen

    1999-11-01

    Trace elements (Ag, As, Ba, Be, Cr, Cd, Cu, Hg, Ni, Pb, Sb, Se, and Tl) were determined in muscle (fillet) of average sized fish (mostly carp, catfish, and sucker) collected from the confluences of major canyons that cross Los Alamos National Laboratory (LANL) lands with the Rio Grande (RG). Also, trace elements were determined in fish from reservoirs upstream (Abiquiu [AR]) and downstream (Cochiti [CR]) of LANL from 1991 through 1999. In general, all of the (mean) trace elements, including Hg, were either at the limits of detection (LOD) or in low concentrations at all study sites. Of the trace elements (e.g., Ba, Cu, and Hg) that were found to be above the LOD in fish muscle collected from LANL canyons/RG, none were in significantly higher (p < 0.05) concentrations than in muscle of fish collected from background locations. Mercury concentrations (mean of means) in fish from AR (all other trace elements were at LOD) were significantly higher (p < 0.10) than Hg concentrations in fish from CR, and Hg concentrations in fish collected from both reservoirs exhibited significantly (AR = p <0.05 and CR = p < 0.10) decreasing trends over time.

  2. Ring trial among National Reference Laboratories for parasites to detect Trichinella spiralis larvae in pork samples according to the EU directive 2075/2005.

    PubMed

    Marucci, Gianluca; Pezzotti, Patrizio; Pozio, Edoardo

    2009-02-23

    To control Trichinella spp. infection in the European Union, all slaughtered pigs should be tested by one of the approved digestion methods described in EU directive 2075/2005. The aim of the present work was to evaluate, by a ring trial, the sensitivity of the digestion method used at the National Reference Laboratories for Parasites (NRLP). These Laboratories are responsible for the quality of the detection method in their own country. Of the 27 EU countries, only three (Hungary, Luxembourg and Malta) did not participate in the ring trial. Each participating laboratory received 10 samples of 100g of minced pork containing 3-5 larvae (3 samples), 10-20 larvae (3 samples), 30-50 larvae (3 samples), and one negative control. In each positive sample, there were living Trichinella spiralis larvae without the collagen capsule, obtained by partial artificial digestion of muscle tissue from infected mice. No false positive sample was found in any laboratories, whereas nine laboratories (37.5%) failed to detect some positive samples with the percentage of false negatives ranging from 11 to 100%. The variation between expected and reported larval counts observed among the participating laboratories was statistically significant. There was a direct correlation between the consistency of the results and the use of a validated/accredited digestion method. Conversely, there was no correlation between the consistency of the results and the number of digestions performed yearly by the NRLP. These results support the importance of validating the test.

  3. National Media Laboratory

    NASA Technical Reports Server (NTRS)

    Clark, Robert

    1992-01-01

    A review of the National Media Laboratory (NML) is presented. The mission of the NML is to support current government user data storage needs and assist them in getting the most efficient 'commercial' solutions in the future. The motivation for a National Media Laboratory is as follows: recording systems are the major government image and data exploitation bottleneck; government data recording performance and storage requirements lead commercial practice by 3-5 years; the supporting commercial recorder industry is large but principally focused on video not data formats; lack of standards; and lack of transfer of commercial knowledge base to program offices and operational sites.

  4. The role of leptospirosis reference laboratories.

    PubMed

    Hartskeerl, Rudy A; Smythe, Lee D

    2015-01-01

    The general goal of reference centres is to support the community, from diagnostic laboratories to research institutions, in the execution of their work by providing reference strains and reagents and giving instructions and recommendations to individual colleagues and national and international organisations on a wide variety of issues. There are different levels of reference centres, from local to international, with an increasing package of tasks and responsibilities. Local reference centres might limit activities to diagnostic confirmation by applying standard testing, while international reference centres cover a wider range of activities from design, validation and harmonisation of diagnostic and reference technologies to international monitoring associated with recommendations on the global burden and distribution of leptospirosis and its prevention and control to national and international health decision makers. This chapter focusses on four major pillars constituting reference tasks in addition to the obvious provision of reference substances, i.e. Research and training, Diagnosis, Identification of Leptospira and Surveillance. Due to financial and organisational constraints, reference centres are restricted in their capacity for basic research and consequently focus on applied research into various aspects of leptospirosis. They offer training, either individually or groupwise, that might vary from standard technologies to novel sophisticated methodologies, depending on the need and requests of the trainee. Most reference centres are involved in the confirmation of preliminary diagnosis obtained at peripheral levels, such as local hospitals and health centres, while other major activities involve the design and validation of diagnostics, their international harmonisation and quality assurance. Identification of causative Leptospira strains (or serovars) is key to the identification of infection sources and is critical for surveillance. Hence, reference

  5. A Retrospective Analysis of Urine Drugs of Abuse Immunoassay True Positive Rates at a National Reference Laboratory.

    PubMed

    Johnson-Davis, Kamisha L; Sadler, Aaron J; Genzen, Jonathan R

    2016-03-01

    Urine drug screens are commonly performed to identify drug use or monitor adherence to drug therapy. The purpose of this retrospective study was to evaluate the true positive and false positive rates of one of our in-house urine drug screen panels. The urine drugs of abuse panel studied consists of screening by immunoassay then positive immunoassay results were confirmed by mass spectrometry. Reagents from Syva and Microgenics were used for the immunoassay screen. The screen was performed on a Beckman AU5810 random access automated clinical analyzer. The percent of true positives for each immunoassay was determined. Agreement with previously validated GC-MS or LC-MS-MS confirmatory methods was also evaluated. There were 8,825 de-identified screening results for each of the drugs in the panel, except for alcohol (N = 2,296). The percent of samples that screened positive were: 10.0% for amphetamine/methamphetamine/3,4-methylenedioxy-methamphetamine (MDMA), 12.8% for benzodiazepines, 43.7% for opiates (including oxycodone) and 20.3% for tetrahydrocannabinol (THC). The false positive rate for amphetamine/methamphetamine was ∼14%, ∼34% for opiates (excluding oxycodone), 25% for propoxyphene and 100% for phencyclidine and MDMA immunoassays. Based on the results from this retrospective study, the true positive rate for THC drug use among adults were similar to the rate of illicit drug use in young adults from the 2013 National Survey; however, our positivity rate for cocaine was higher than the National Survey.

  6. Survey of the Diagnostic Retooling Process in National TB Reference Laboratories, with Special Focus on Rapid Speciation Tests Endorsed by WHO in 2007

    PubMed Central

    van Kampen, Sanne C.; Oskam, Linda; Tuijn, Coosje J.; Klatser, Paul R.

    2012-01-01

    Background Successful integration of new diagnostics in national tuberculosis (TB) control programs, also called ‘retooling’, is highly dependent on operational aspects related to test availability, accessibility and affordability. This survey aimed to find out whether recommendations to use new diagnostics lead to successful retooling in high TB endemic countries, using immunochromatographic tests (ICTs) for TB culture speciation as a case study. ICTs are recommended to accurately confirm the presence of bacteria of the Mycobacterium tuberculosis complex in liquid culture isolates. Methods and Findings Questionnaires were sent to national TB reference laboratories (NRLs) in 42 high TB endemic countries to address their access to information on ICT implementation, logistics related to availability, accessibility and affordability of ICTs, and testing algorithms. Results from 16 responding countries indicated that half of the NRLs were aware of the contents of WHO guidance documents on liquid culture and ICT implementation, as well as their eligibility for a negotiated pricing agreement for ICT procurement. No major issues with availability and accessibility of ICTs were raised. When asked about testing algorithms, ICTs were not used as stand-alone or first test for TB culture identification as recommended by WHO. Conclusions The low response rate was a limitation of this survey and together with NRLs managers' unawareness of global guidance, suggests a lack of effective communication between partners of the global laboratory network and NRLs. TB tests could become more affordable to high TB endemic countries, if the possibility to negotiate lower prices for commercial products is communicated to them more successfully. NRLs need additional guidance to identify where available technologies can be most usefully implemented and in what order, taking into account long-term laboratory strategies. PMID:22937050

  7. Survey of the diagnostic retooling process in national TB reference laboratories, with special focus on rapid speciation tests endorsed by WHO in 2007.

    PubMed

    van Kampen, Sanne C; Oskam, Linda; Tuijn, Coosje J; Klatser, Paul R

    2012-01-01

    Successful integration of new diagnostics in national tuberculosis (TB) control programs, also called 'retooling', is highly dependent on operational aspects related to test availability, accessibility and affordability. This survey aimed to find out whether recommendations to use new diagnostics lead to successful retooling in high TB endemic countries, using immunochromatographic tests (ICTs) for TB culture speciation as a case study. ICTs are recommended to accurately confirm the presence of bacteria of the Mycobacterium tuberculosis complex in liquid culture isolates. Questionnaires were sent to national TB reference laboratories (NRLs) in 42 high TB endemic countries to address their access to information on ICT implementation, logistics related to availability, accessibility and affordability of ICTs, and testing algorithms. Results from 16 responding countries indicated that half of the NRLs were aware of the contents of WHO guidance documents on liquid culture and ICT implementation, as well as their eligibility for a negotiated pricing agreement for ICT procurement. No major issues with availability and accessibility of ICTs were raised. When asked about testing algorithms, ICTs were not used as stand-alone or first test for TB culture identification as recommended by WHO. The low response rate was a limitation of this survey and together with NRLs managers' unawareness of global guidance, suggests a lack of effective communication between partners of the global laboratory network and NRLs. TB tests could become more affordable to high TB endemic countries, if the possibility to negotiate lower prices for commercial products is communicated to them more successfully. NRLs need additional guidance to identify where available technologies can be most usefully implemented and in what order, taking into account long-term laboratory strategies.

  8. [Evaluation of the distribution of non-tuberculous mycobacteria strains isolated in National Tuberculosis Reference Laboratory in 2009-2010, Turkey].

    PubMed

    Albayrak, Nurhan; Simşek, Hülya; Sezen, Figen; Arslantürk, Ahmet; Tarhan, Gülnur; Ceyhan, Ismail

    2012-10-01

    Non-tuberculous mycobacteria (NTM) are commonly encountered environmental bacteria, and most of them are associated with lung diseases. Diagnosis of infections caused by NTM is based on clinical, radiological and microbiological findings. The aim of this study was to investigate the distribution of non-tuberculous mycobacterial species isolated from clinical specimens as etiologic agents. The NTM strains isolated from clinical specimens in National Tuberculosis Reference Laboratory (NTRL), together with the strains that were sent to NTRL for the advanced identification of non-tuberculous mycobacterial species that have clinical or microbiological significance, were analysed retrospectively. The strains belonged to January 2009 - December 2010 period. If the same NTM type was isolated more than once in the clinical specimens of a patient, then it was defined microbiologically as a causative agent. Identification of mycobacteria species was performed by using a commercial line-probe assay (GenoType Mycobacterium CM/AS; Hain Lifescience, Germany). In our study, pulmonary and non-pulmonary samples obtained from 206 patients yielded mycobacterial growth in their cultures, and of them 24 (11.7%) were identified as NTM. On the other hand, 51 of the 101 samples sent to NTRL for identification were confirmed as NTM. Of the patients who were found to be infected with NTM (n= 75), 59 (78.7%) were male and the mean age was 50.9 ± 18.8 years. The most frequently identified NTM species was M.fortuitum (33.3%, n= 25), followed by M.abscessus (18.7%, n= 14), M.gordonae (10.7%, n= 8) and M.avium (%8; n= 6). The other types of NTM species identified in our laboratory were M.chelonae (n= 3), M.intracellulare (n= 3), M.kansasii (n= 3), M.peregrinum (n= 2), M.scrofulaceum (n= 2), M.szulgai (n= 2), M.celatum (n= 1), M.haemophilum (n= 1), M.smegmatis (n= 1) and M.xenopi (n= 1). Rapidly growing NTM species (M.fortuitum and M.abscessus) were the most frequent (52%) species isolated in our

  9. Establishing reference intervals in the coagulation laboratory.

    PubMed

    Castellone, D D

    2017-05-01

    Obtaining a reference interval (RI) is a challenge for any laboratory and becomes more complicated in the coagulation laboratory due to testing on samples with limited stability on reagents that are poorly standardized. Reference intervals are required to be able to evaluate results in relation to a patients' hemostatic disorder. This becomes one of the most important tasks conducted in the coagulation laboratory. However, many laboratories lack the time, finances and in many cases the expertise to conduct this study. Many RI are obtained from package inserts, or from publications written by experts in lieu of laboratories conducting their own studies. An overview of validating reference intervals and options for verifying or transference of reference intervals is discussed. Based on the confidence interval and the acceptability of risk laboratories are willing to accept, coagulation laboratories have options to conduct robust studies for their RI. Data mining or global reference studies may help to provide data for age specific ranges. Pre-analytical variables and selection of healthy subjects have the largest impact on coagulation testing outcomes and need to be well controlled during the establishment of reference intervals. Laboratories have options in lieu of conducting a full validation on how to verify RI based on smaller RI studies or transference of RI after determining compatibility of the original RI study. © 2017 John Wiley & Sons Ltd.

  10. Analysis of vitamin D status at two academic medical centers and a national reference laboratory: result patterns vary by age, gender, season, and patient location

    PubMed Central

    2013-01-01

    Background Testing for 25-hydroxyvitamin D [25(OH)D] has increased dramatically in recent years. The present report compares overall utilization and results for 25(OH)D orders at two academic medical centers - one in New York and one in Iowa – in order to characterize the vitamin D status of our inpatient and outpatient populations. Results are also compared to those from a national reference laboratory to determine whether patterns at these two institutions reflect those observed nationally. Methods Retrospective data queries of 25(OH)D orders and results were conducted using the laboratory information systems at Weill Cornell Medical College / New York Presbyterian Hospital (WCMC), University of Iowa Hospitals and Clinics (UIHC), and ARUP Laboratories (ARUP). Chart review was conducted for cases with very high or low serum 25(OH)D levels in the WCMC and UIHC datasets. Results The majority of tests were ordered on females and outpatients. Average serum 25(OH)D levels were higher in female versus male patients across most ages in the WCMC, UIHC, and ARUP datasets. As expected, average serum 25(OH)D levels were higher in outpatients than inpatients. Serum 25(OH)D levels showed seasonal periodicity, with average levels higher in summer than winter and correlating to regional UV index. Area plots demonstrated a peak of increased 25(OH)D insufficiency / deficiency in adolescent females, although overall worse 25(OH)D status was found in male versus female patients in the WCMC, UIHC, and ARUP datasets. Surprisingly, improved 25(OH)D status was observed in patients starting near age 50. Finally, chart review of WCMC and UIHC datasets revealed over-supplementation (especially of ≥ 50,000 IU weekly doses) in the rare cases of very high 25(OH)D levels. General nutritional deficiency and/or severe illness was found in most cases of severe 25(OH)D deficiency. Conclusions 25(OH)D status of patients seen by healthcare providers varies according to age, gender, season

  11. Wide variability in laboratory reference values for serum testosterone.

    PubMed

    Lazarou, Stephen; Reyes-Vallejo, Luis; Morgentaler, Abraham

    2006-11-01

    The laboratory determination of testosterone levels consistent with a diagnosis of hypogonadism is complicated by the availability of multiple testosterone assays and varying reference ranges. To assess current laboratory practices regarding availability of testosterone assays and use of reference values. A telephone survey of 12 academic, 12 community medical laboratories, and one national laboratory. Types of androgen assays offered and determination of reference values. All of the academic and eight of the community centers performed total testosterone testing. Free testosterone was performed in-house by six of the 12 academic and one community center. Testing for bioavailable testosterone, free androgen index, and percent free testosterone was performed in-house by no more than two centers. There were eight and four different assays used for total and free testosterone, respectively. One national laboratory offered equilibrium dialysis measurement of free testosterone. Of the 25 labs, there were 17 and 13 different sets of reference values for total and free testosterone, respectively. The low reference value for total testosterone ranged from 130 to 450 ng/dL (350% difference), and the upper value ranged from 486 to 1,593 ng/dL (325% difference). Age-adjusted reference values were applied in four centers for total testosterone and in seven labs for free testosterone. All reference values were based on a standard statistical model without regard for clinical aspects of hypogonadism. Twenty-three of the 25 lab directors responded that clinically relevant testosterone reference ranges would be preferable to current standards. Laboratory reference values for testosterone vary widely, and are established without clinical considerations.

  12. Brookhaven National Laboratory

    MedlinePlus

    ... the nation; and perform cross-disciplinary research on climate change, sustainable energy, and Earth’s ecosystems. Research Themes Research Programs Overview Core Capabilities Photon Sciences QCD Matter Energy Research ... Env. & Biosci. Upcoming Conferences OCT 11 Wednesday Brookhaven ...

  13. [Tasks and duties of veterinary reference laboratories for food borne zoonoses].

    PubMed

    Ellerbroek, Lüppo; Alter, T; Johne, R; Nöckler, K; Beutin, L; Helmuth, R

    2009-02-01

    Reference laboratories are of central importance for consumer protection. Field expertise and high scientific competence are basic requirements for the nomination of a national reference laboratory. To ensure a common approach in the analysis of zoonotic hazards, standards have been developed by the reference laboratories together with national official laboratories on the basis of Art. 33 of Directive (EG) No. 882/2004. Reference laboratories function as arbitrative boards in the case of ambivalent or debatable results. New methods for detection of zoonotic agents are developed and validated to provide tools for analysis, e. g., in legal cases, if results from different parties are disputed. Besides these tasks, national reference laboratories offer capacity building and advanced training courses and control the performance of ring trials to ensure consistency in the quality of analyses in official laboratories. All reference laboratories work according to the ISO standard 17025 which defines the grounds for strict laboratory quality rules and in cooperation with the respective Community Reference Laboratories (CRL). From the group of veterinary reference laboratories for food-borne zoonoses, the national reference laboratories are responsible for Listeria monocytogenes, for Campylobacter, for the surveillance and control of viral and bacterial contamination of bivalve molluscs, for E. coli, for the performance of analysis and tests on zoonoses (Salmonella), and from the group of parasitological zoonotic agents, the national reference laboratory for Trichinella.

  14. Los Alamos National Laboratory A National Science Laboratory

    SciTech Connect

    Chadwick, Mark B.

    2012-07-20

    Our mission as a DOE national security science laboratory is to develop and apply science, technology, and engineering solutions that: (1) Ensure the safety, security, and reliability of the US nuclear deterrent; (2) Protect against the nuclear threat; and (3) Solve Energy Security and other emerging national security challenges.

  15. A National Natural Laboratory.

    ERIC Educational Resources Information Center

    Cohn, Jeffrey P.

    1994-01-01

    Describes the Savannah River Site, a national environmental research park that shelters wild animals and idle nuclear reactors. Outlines research conducted at the site that focuses on the recovery of ecosystems after disturbance related to the operation of nuclear reactors and other land uses. (LZ)

  16. A National Natural Laboratory.

    ERIC Educational Resources Information Center

    Cohn, Jeffrey P.

    1994-01-01

    Describes the Savannah River Site, a national environmental research park that shelters wild animals and idle nuclear reactors. Outlines research conducted at the site that focuses on the recovery of ecosystems after disturbance related to the operation of nuclear reactors and other land uses. (LZ)

  17. Vertebrates of the Idaho National Engineering Laboratory

    SciTech Connect

    Arthur, W.J.; Connelly, J.W.; Halford, D.K.; Reynolds, T.D.

    1984-07-01

    Abundance, habitat use, and seasonal occurrence are reported for the 5 fish, 1 amphibian, 9 reptile, 159 bird and 37 mammal species recorded on the Idaho National Engineering Laboratory National Environmental Research Park in southeastern Idaho. An additional 45 species, for which site records are lacking, were listed as possibly occurring because portions of their documented range and habitat overlap the INEL. Species of special concern on the federal and state level are discussed. 41 references, 4 tables.

  18. Los Alamos National Laboratory

    SciTech Connect

    Dogliani, Harold O

    2011-01-19

    The purpose of the briefing is to describe general laboratory technical capabilities to be used for various groups such as military cadets or university faculty/students and post docs to recruit into a variety of Los Alamos programs. Discussed are: (1) development and application of high leverage science to enable effeictive, predictable and reliability outcomes; (2) deter, detect, characterize, reverse and prevent the proliferation of weapons of mass destruction and their use by adversaries and terrorists; (3) modeling and simulation to define complex processes, predict outcomes, and develop effective prevention, response, and remediation strategies; (4) energetic materials and hydrodynamic testing to develop materials for precise delivery of focused energy; (5) materials cience focused on fundamental understanding of materials behaviors, their quantum-molecular properties, and their dynamic responses, and (6) bio-science to rapidly detect and characterize pathogens, to develop vaccines and prophylactic remedies, and to develop attribution forensics.

  19. National Water Quality Laboratory Profile

    USGS Publications Warehouse

    Raese, Jon W.

    1994-01-01

    The National Water Quality Laboratory determines organic and inorganic constituents in samples of surface and ground water, river and lake sediment, aquatic plant and animal material, and precipitation collected throughout the United States and its territories by the U.S. Geological Survey. In water year 1994, the Laboratory produced more than 900,000 analytical results for about 65,000 samples. The Laboratory also coordinates an extensive network of contract laboratories for the determination of radiochemical and stable isotopes and work for the U.S. Department of Defense Environmental Contamination Hydrology Program. Heightened concerns about water quality and about the possible effects of toxic chemicals at trace and ultratrace levels have contributed to an increased demand for impartial, objective, and independent data.

  20. PYROPROCESSING PROGRESS AT IDAHO NATIONAL LABORATORY

    SciTech Connect

    Solbrig, Chuck; B. R. Westphal; Johnson, T.; Li, S.; Marsden, K.; Goff, K. M.

    2007-09-01

    At the end of May 2007, 830 and 2600 kilograms of EBR-II driver and blanket metal fuel have been treated by a pyroprocess since spent fuel operations began in June 1996. A new metal waste furnace has completed out-of-cell testing and is being installed in the Hot Fuel Examination Facility. Also, ceramic waste process development and qualification is progressing so integrated nuclear fuel separations and high level waste processes will exist at Idaho National Laboratory. These operations have provided important scale-up and performance data on engineering scale operations. Idaho National Laboratory is also increasing their laboratory scale capabilities so new process improvements and new concepts can be tested before implementation at engineering scale. This paper provides an overview of recent achievements and provides the interested reader references for more details.

  1. Argonne National Laboratory 1985 publications

    SciTech Connect

    Kopta, J.A.; Hale, M.R.

    1987-08-01

    This report is a bibliography of scientific and technical 1985 publications of Argonne National Laboratory. Some are ANL contributions to outside organizations' reports published in 1985. This compilation, prepared by the Technical Information Services Technical Publications Section (TPB), lists all nonrestricted 1985 publications submitted to TPS by Laboratory's Divisions. The report is divided into seven parts: Journal Articles - Listed by first author, ANL Reports - Listed by report number, ANL and non-ANL Unnumbered Reports - Listed by report number, Non-ANL Numbered Reports - Listed by report number, Books and Book Chapters - Listed by first author, Conference Papers - Listed by first author, Complete Author Index.

  2. POLLUTION PREVENTION OPPORTUNITY ASSESSMENT - GEOCHEMISTRY LABORATORY AT SANDIA NATIONAL LABORATORIES

    EPA Science Inventory

    These reports summarize pollution prevention opportunity assessments conducted jointly by EPA and DOE at the Geochemistry Laboratory and the Manufacturing and Fabrication Repair Laboratory at the Department of Energy's Sandia National Laboratories facility in Albuquerque, New Mex...

  3. POLLUTION PREVENTION OPPORTUNITY ASSESSMENT - GEOCHEMISTRY LABORATORY AT SANDIA NATIONAL LABORATORIES

    EPA Science Inventory

    These reports summarize pollution prevention opportunity assessments conducted jointly by EPA and DOE at the Geochemistry Laboratory and the Manufacturing and Fabrication Repair Laboratory at the Department of Energy's Sandia National Laboratories facility in Albuquerque, New Mex...

  4. National Laboratories and Internatioanl Partnering

    SciTech Connect

    Eagan, R.J.; Gauster, W.B.; Hartley, D.L.; Jones, G.J.

    1998-12-07

    For nearly fifty years the US held a dominant position in research and development in the free world. The situation has changed dramatically in the last decade. Countries around the world realize that to foster sustainable economic growth, they must build and maintain a foundation in science and technology. The time in which a country could base its gross national product solely on extraction of raw materials or on people-intensive manufacturing is drawing to a close. The funding for research and development has been growing in the rest of the world, while US expenditures have not kept pace. In 1961, the United States funded 71 `?40 of the world's R&D. It is estimated that the US contribution to research and development fimding today has reached the 3 3o/0 level, and will drop to 26o/0 of the world's total by 2003.1 In 1981 US government spending per capita on non-defense research and development was nearly fifty percent above our major competitors; by 2002 it is projected to be f@ percent below them.2 This trend has a profound impact on how research and development institutions in the United States plan for their future technical growth. Sandia National Laboratories, as one of the largest US-government tided research establishments, has been watching this trend for some time. %ndi~ focusing on the Laboratories' missions in nuclear weapons and related defense systems, energy security, environmental integrity, and emerging national challenges, is committed to bringing the best in world-class technology to bear on the nation's problems. We realize maintaining our state-of-the-art technolo=~ base requires we look not only to domestic sources in universities, industries and other laboratories, but also to sources overseas. The realization that we must be "worldwide gatherers of technology" has led Sandia National Laboratories to consider the question of international partnering in some detaiI. As a national laboratory with a national security mission we are well aware

  5. Lawrence Livermore National Laboratory Environmental Report 2012

    SciTech Connect

    Jones, Henry E.; Armstrong, Dave; Blake, Rick G.; Bertoldo, Nicholas A.; Cerruti, Steven J.; Fish, Craig; Dibley, Valerie R.; Doman, Jennifer L.; Grayson, Allen R.; Heidecker, Kelly R.; Hollister, Rod K.; Kumamoto, Gene; MacQueen, Donald H.; Nelson, Jennifer C.; Ottaway, Heather L.; Paterson, Lisa E.; Revelli, Michael A.; Rosene, Crystal A.; Terrill, Alison A.; Wegrecki, Anthony M.; Wilson, Kent R.; Woollett, Jim S.

    2013-09-19

    Lawrence Livermore National Laboratory (LLNL) is a premier research laboratory that is part of the National Nuclear Security Administration (NNSA) within the U.S. Department of Energy (DOE). As a national security laboratory, LLNL is responsible for ensuring that the nation’s nuclear weapons remain safe, secure, and reliable. The Laboratory also meets other pressing national security needs, including countering the proliferation of weapons of mass destruction and strengthening homeland security, and conducting major research in atmospheric, earth, and energy sciences; bioscience and biotechnology; and engineering, basic science, and advanced technology. The Laboratory is managed and operated by Lawrence Livermore National Security, LLC (LLNS), and serves as a scientific resource to the U.S. government and a partner to industry and academia. LLNL operations have the potential to release a variety of constituents into the environment via atmospheric, surface water, and groundwater pathways. Some of the constituents, such as particles from diesel engines, are common at many types of facilities while others, such as radionuclides, are unique to research facilities like LLNL. All releases are highly regulated and carefully monitored. LLNL strives to maintain a safe, secure and efficient operational environment for its employees and neighboring communities. Experts in environment, safety and health (ES&H) support all Laboratory activities. LLNL’s radiological control program ensures that radiological exposures and releases are reduced to as low as reasonably achievable to protect the health and safety of its employees, contractors, the public, and the environment. LLNL is committed to enhancing its environmental stewardship and managing the impacts its operations may have on the environment through a formal Environmental Management System. The Laboratory encourages the public to participate in matters related to the Laboratory’s environmental impact on the

  6. Lawrence Livermore National Laboratory Environmental Report 2013

    SciTech Connect

    Jones, H. E.; Bertoldo, N. A.; Blake, R. G.; Cerruti, S. J.; Dibley, V. R.; Doman, J. L.; Fish, C. B.; Grayson, A. R.; Heidecker, K. R.; Kumamoto, G.; MacQueen, D. H.; Montemayor, W. E.; Ottaway, H. L.; Paterson, L. E.; Revelli, M. A.; Rosene, C. A.; Terrill, A. A.; Wegrecki, A. M.; Wilson, K. R.; Woollett, J. S.; Veseliza, R.

    2014-10-01

    Lawrence Livermore National Laboratory (LLNL) is a premier research laboratory that is part of the National Nuclear Security Administration (NNSA) within the U.S. Department of Energy (DOE). As a national security laboratory, LLNL is responsible for ensuring that the nation’s nuclear weapons remain safe, secure, and reliable. The Laboratory also meets other pressing national security needs, including countering the proliferation of weapons of mass destruction and strengthening homeland security, and conducting major research in atmospheric, earth, and energy sciences; bioscience and biotechnology; and engineering, basic science, and advanced technology. The Laboratory is managed and operated by Lawrence Livermore National Security, LLC (LLNS), and serves as a scientific resource to the U.S. government and a partner to industry and academia. LLNL operations have the potential to release a variety of constituents into the environment via atmospheric, surface water, and groundwater pathways. Some of the constituents, such as particles from diesel engines, are common at many types of facilities while others, such as radionuclides, are unique to research facilities like LLNL. All releases are highly regulated and carefully monitored. LLNL strives to maintain a safe, secure and efficient operational environment for its employees and neighboring communities. Experts in environment, safety and health (ES&H) support all Laboratory activities. LLNL’s radiological control program ensures that radiological exposures and releases are reduced to as low as reasonably achievable to protect the health and safety of its employees, contractors, the public, and the environment. LLNL is committed to enhancing its environmental stewardship and managing the impacts its operations may have on the environment through a formal Environmental Management System. The Laboratory encourages the public to participate in matters related to the Laboratory’s environmental impact on the

  7. The Validation and Implications of Using Whole Genome Sequencing as a Replacement for Traditional Serotyping for a National Salmonella Reference Laboratory

    PubMed Central

    Yachison, Chris A.; Yoshida, Catherine; Robertson, James; Nash, John H. E.; Kruczkiewicz, Peter; Taboada, Eduardo N.; Walker, Matthew; Reimer, Aleisha; Christianson, Sara; Nichani, Anil; Paccagnella, Ana; Nadon, Celine

    2017-01-01

    Salmonella serotyping remains the gold-standard tool for the classification of Salmonella isolates and forms the basis of Canada’s national surveillance program for this priority foodborne pathogen. Public health officials have been increasingly looking toward whole genome sequencing (WGS) to provide a large set of data from which all the relevant information about an isolate can be mined. However, rigorous validation and careful consideration of potential implications in the replacement of traditional surveillance methodologies with WGS data analysis tools is needed. Two in silico tools for Salmonella serotyping have been developed, the Salmonella in silico Typing Resource (SISTR) and SeqSero, while seven gene MLST for serovar prediction can be adapted for in silico analysis. All three analysis methods were assessed and compared to traditional serotyping techniques using a set of 813 verified clinical and laboratory isolates, including 492 Canadian clinical isolates and 321 isolates of human and non-human sources. Successful results were obtained for 94.8, 88.2, and 88.3% of the isolates tested using SISTR, SeqSero, and MLST, respectively, indicating all would be suitable for maintaining historical records, surveillance systems, and communication structures currently in place and the choice of the platform used will ultimately depend on the users need. Results also pointed to the need to reframe serotyping in the genomic era as a test to understand the genes that are carried by an isolate, one which is not necessarily congruent with what is antigenically expressed. The adoption of WGS for serotyping will provide the simultaneous collection of information that can be used by multiple programs within the current surveillance paradigm; however, this does not negate the importance of the various programs or the role of serotyping going forward. PMID:28649236

  8. Oak Ridge National Laboratory Review

    SciTech Connect

    Krause, C.; Pearce, J.; Zucker, A.

    1992-01-01

    This report presents brief descriptions of the following programs at Oak Ridge National Laboratory: The effects of pollution and climate change on forests; automation to improve the safety and efficiency of rearming battle tanks; new technologies for DNA sequencing; ORNL probes the human genome; ORNL as a supercomputer research center; paving the way to superconcrete made with polystyrene; a new look at supercritical water used in waste treatment; and small mammals as environmental monitors.

  9. Photometrics at Sandia National Laboratories

    SciTech Connect

    McWilliams, J.Y.; Hill, R.A.; Hughes, R.L.

    1990-07-01

    This report highlights Sandia National Laboratories' work in the following areas: photometrics and optical development; still and time-lapse photography; real-time motion photography; high-speed photography; image-motion photography; schlieren photography; ultra-high-speed photography; electronic imaging; shuttered video and high-speed video; infrared imaging radiometry; exoatmospheric photography and videography; microdensitometry and image analysis; and optical system design and development.

  10. Sandia National Laboratories analysis code data base

    SciTech Connect

    Peterson, C.W.

    1994-11-01

    Sandia National Laboratories, mission is to solve important problems in the areas of national defense, energy security, environmental integrity, and industrial technology. The Laboratories` strategy for accomplishing this mission is to conduct research to provide an understanding of the important physical phenomena underlying any problem, and then to construct validated computational models of the phenomena which can be used as tools to solve the problem. In the course of implementing this strategy, Sandia`s technical staff has produced a wide variety of numerical problem-solving tools which they use regularly in the design, analysis, performance prediction, and optimization of Sandia components, systems and manufacturing processes. This report provides the relevant technical and accessibility data on the numerical codes used at Sandia, including information on the technical competency or capability area that each code addresses, code ``ownership`` and release status, and references describing the physical models and numerical implementation.

  11. Argonne National Laboratory 1986 publications

    SciTech Connect

    Kopta, J.A.; Springer, C.J.

    1987-12-01

    This report is a bibliography of scientific and technical 1986 publications of Argonne National Laboratory. Some are ANL contributions to outside organizations' reports published in 1986. This compilation, prepared by the Technical Information Services Technical Publications Section (TPS), lists all nonrestricted 1986 publications submitted to TPS by the Laboratory's Divisions. Author indexes list ANL authors only. If a first author is not an ANL employee, an asterisk in the bibliographic citation indicates the first ANL author. The report is divided into seven parts: Journal Articles -- Listed by first author; ANL Reports -- Listed by report number; ANL and non-ANL Unnumbered Reports -- Listed by report number; Non-ANL Numbered Reports -- Listed by report number; Books and Book Chapters -- Listed by first author; Conference Papers -- Listed by first author; and Complete Author Index.

  12. Directory of Accredited Laboratories, 1991. National Voluntary Laboratory Accreditation Program. Final report

    SciTech Connect

    Trahey, N.M.; White, V.R.; Horlick, J.

    1991-04-01

    The annual Directory provides a listing of laboratories accredited as of March 1, 1991, by the National Institute of Standards and Technology, National Voluntary Laboratory Accreditation Program (NVLAP). The names of approximately 900 laboratories in 15 fields of testing are included. A brief description of the NVLAP program is given, and a summary of laboratory participation is provided. To aid the user, indexes cross reference the laboratories by company name, NVLAP Lab Code Number, field of testing, and geographic location (state or country). A listing of the test methods (scope of accreditation) is provided for each laboratory.

  13. Comparison of a spectrophotometric microdilution method with RPMI-2% glucose with the National Committee for Clinical Laboratory Standards reference macrodilution method M27-P for in vitro susceptibility testing of amphotericin B, flucytosine, and fluconazole against Candida albicans.

    PubMed Central

    Rodríguez-Tudela, J L; Berenguer, J; Martínez-Suárez, J V; Sanchez, R

    1996-01-01

    The National Committee for Clinical Laboratory Standards has proposed a reference broth macrodilution method for in vitro antifungal susceptibility testing of yeasts (the M27-P method). This method is cumbersome and time-consuming and includes MIC endpoint determination by visual and subjective inspection of growth inhibition after 48 h of incubation. An alternative microdilution procedure was compared with the M27-P method for determination of the amphotericin B, flucytosine, and fluconazole susceptibilities of 8 American Type Culture Collection strains (6 of them were quality control or reference strains) and 50 clinical isolates of candida albicans. This microdilution method uses as culture medium RPMI 1640 supplemented with 18 g of glucose per liter (RPMI-2% glucose). Preparation of drugs, basal medium, and inocula was done by following the recommendations of the National Committee for Clinical Laboratory Standards. The MIC endpoint was calculated objectively from the turbidimetric data read at 24 h. Increased growth of C. albicans in RPMI-2% glucose and its spectrophotometric reading allowed for the rapid (24 h) and objective calculation of MIC endpoints compared with previous microdilution methods with standard RPMI 1640. Nevertheless, good agreement was shown between the M27-P method and this microdilution test. The MICs obtained for the quality control or reference strains by the microdilution method were in the ranges published for those strains. For clinical isolates, the percentages of agreement were 100% for amphotericin B and fluconazole and 98.1% for flucytosine. These data suggest that this microdilution method may serve as a less subjective and more rapid alternative to the M27-P method for antifungal susceptibility testing of yeasts. PMID:8878570

  14. Minutes of the Fourth Annual Meeting of the Panel on Reference Nuclear Data, Brookhaven National Laboratory, November 1-2, 1979. [BNL, Nov. 1-2, 1979

    SciTech Connect

    Burrows, T.W.; Stewart, L.; Coyne, J.J.

    1980-06-01

    After the welcome and approval of the agenda and of the minutes of the Third Annual Meeting, the participants turned to reactor physics data needs, CTR data needs, status of international and national cooperation, status and availability of data files, election of officers, status of publications, biomedical data needs, and miscellaneous action items from the Third Meeting. A summary of recommendations and action items is given. Eighteen appendixes are included. (RWR)

  15. Cost-containment and the use of reference laboratories.

    PubMed

    Shaw, S T; Miller, J M

    1985-12-01

    Hospital laboratories and hospital-independent reference laboratories will need to change in order to provide comprehensive, medically appropriate, and reasonably priced laboratory services in the cost-containment age we are entering. The change must be economically and technologically innovative and relevant to society's next generation of health care needs. Hospital laboratories and commercial laboratories may become weaker or stronger relative to one another, but our guess is that they will ultimately become more like one another or even may join forces to provide optimal patient care in the future. Until that time comes, hospital laboratories must decide whether to employ reference laboratory services more or less, enter a joint venture with a reference laboratory, or become a reference laboratory. Some of the items that could be considered in arriving at this decision are listed in Table 2. Some items favor hospital laboratories; some favor reference laboratories; some are a toss-up; and some suggest there are advantages in a team approach. For the present, we believe there are many arguments favoring a continuation and possibly even an expansion of hospital laboratory services, but this will likely be most feasible in financially sound and progressive hospitals having forward-looking administrators and imaginative but fiscally minded laboratory directors and managers. If decisions are made to send more tests to reference laboratories, each hospital or user laboratory must seek the best and most cost-effective services available. Various financial, technical, and medical considerations are described that should aid in the evaluation of where to have tests performed. We have provided suggestions on how agreements with reference laboratories can be established in either a formal (contractual) or an informal (verbal) way. Additionally, we have described methods for evaluating (or monitoring) the quality and quantity of services received from a reference

  16. Pharmacogenomics Implementation: Considerations for Selecting a Reference Laboratory.

    PubMed

    Vo, Teresa T; Bell, Gillian C; Owusu Obeng, Aniwaa; Hicks, J Kevin; Dunnenberger, Henry M

    2017-09-01

    One of the initial steps for implementing pharmacogenomics into routine patient care is selecting an appropriate clinical laboratory to perform the testing. With the rapid advances in genotyping technologies, many clinical laboratories are now performing pharmacogenomic testing. Selection of a reference laboratory depends on whether a particular genotype assay is already performed by an internal health care organization laboratory or only available externally. Other factors for consideration are coverage of genomic variants important for the patient population, technical support, and cost. In some instances, the decision to select a particular reference laboratory may be the responsibility of the clinician who is recommending genomic interrogation. Only limited guidance is available that describes the laboratory characteristics to consider when selecting a reference laboratory. We provide practical considerations for selecting a clinical laboratory for pharmacogenomic testing broadly categorized into four domains: pharmacogene and variant selection; logistics; reporting of results; and test costs along with reimbursement. © 2017 Pharmacotherapy Publications, Inc.

  17. International aspects of Oak Ridge National Laboratory

    SciTech Connect

    Trivelpiece, A.W.

    1990-01-01

    The national laboratories of the Department of Energy can rightly claim to be called international laboratories because of their role in international research and development activities. These laboratories have staff that pursue internationally acclaimed research with both national and international colleagues and have facilities that support these endeavors.

  18. Laboratory-based investigation of suspected mumps cases submitted to the German National Reference Centre for Measles, Mumps, and Rubella, 2008 to 2013.

    PubMed

    Mankertz, Annette; Beutel, Ulrike; Schmidt, Franz-Josef; Borgmann, Stefan; Wenzel, Jürgen J; Ziegler, Peter; Weißbrich, Benedikt; Santibanez, Sabine

    2015-10-01

    From 2008 to 2013, sample sets from 534 patients displaying clinical symptoms of mumps were submitted to the German Reference Centre for Measles, Mumps and Rubella. Mumps virus infection was confirmed in 216 cases (40%) by PCR and/or serology. Confirmed cases were more frequently seen in male than in female patients (128 vs. 81); the age group predominantly affected was 15 to 29 years old (65%, median age: 26.4 years). The majority of the confirmed cases had a remote history of vaccination with one or two doses of a mumps-containing vaccine (69%). Our results indicate that mumps virus caused two outbreaks in Bavaria in 2008 and 2010/2011 and a third one in Lower Saxony in 2011. Mumps virus genotype G was preponderantly detected from 2008 to 2013. For 107 of the 216 patients with a confirmed mumps infection, we correlated the results from PCR and serology. PCR detected cases during the first week after onset of symptoms (74% positive results). PCR worked best with throat swabs and oral fluids (61% and 60% positive results, respectively). IgM was more reliable with a longer time after onset of symptoms (67%), but indirect IgM serology was of insufficient sensitivity for vaccinated mumps cases (30%); the IgM μ-capture assay detected more cases in this group. Mumps virus is able to initiate an infection in vaccinated patients (secondary vaccine failure, SVF) although it is unclear to what extent. Since SVF does occur in highly vaccinated populations and IgM will not increase to detectable levels in all SVF patients, we strongly recommend using PCR plus serology tests to avoid false-negative diagnoses in vaccinated individuals with clinical signs of mumps. Copyright © 2015 Elsevier GmbH. All rights reserved.

  19. Proficiency Program for Real-Time PCR Diagnosis of Bordetella pertussis Infections in French Hospital Laboratories and at the French National Reference Center for Whooping Cough and other Bordetelloses▿ †

    PubMed Central

    Caro, Valérie; Guiso, Nicole; Alberti, Corinne; Liguori, Sandrine; Burucoa, Christophe; Couetdic, Gérard; Doucet-Populaire, Florence; Ferroni, Agnès; Papin-Gibaud, Sophie; Grattard, Florence; Réglier-Poupet, Hélène; Raymond, Josette; Soler, Catherine; Bouchet, Sylvie; Charreau, Sandrine; Couzon, Brigitte; Leymarie, Isabelle; Tavares, Nicole; Choux, Mathilde; Bingen, Edouard; Bonacorsi, Stéphane

    2009-01-01

    With the support of a ministerial program for innovative and expensive technologies, dedicated to the economic evaluation of laboratory diagnosis of pertussis by real-time PCR, external quality assessment for real-time IS481 PCR was carried out. Coordinated by the National Centre of Reference of Pertussis and other Bordetelloses (NCR), this study aimed to harmonize and to assess the performances of eight participating microbiology hospital laboratories throughout the French territory. Between January 2006 and February 2007, 10 proficiency panels were sent by the NCR (ascending proficiency program), representing a total of 49 samples and including eight panels to analyze and evaluate the global sensitivity and specificity of real-time PCR, one to assess the limit of detection, and one to evaluate nucleic acid extraction methods. As part of the descending proficiency program, extracted DNA from clinical samples was sent by the eight participating laboratories in different panels and analyzed by the NCR. In the ascending proficiency analysis, the sensitivity and specificity of the real-time PCR methods were 92.2% and 94.3%, respectively. The limit of detection of the different methods ranged between 0.1 and 1 fg/μl (0.2 to 2 CFU/μl). The nucleic acid extraction methods showed similar performances. During the descending proficiency analysis, performed with 126 samples, the result of the NCR for 15 samples (11.9%) was discordant with the result obtained by the source laboratory. Despite several initial differences, harmonization was easy and performances were homogeneous. However, the risk of false-positive results remains quite high, and we strongly recommend establishment of uniform quality control procedures performed regularly. PMID:19692562

  20. Proficiency program for real-time PCR diagnosis of Bordetella pertussis infections in French hospital laboratories and at the French National Reference Center for Whooping Cough and other Bordetelloses.

    PubMed

    Caro, Valérie; Guiso, Nicole; Alberti, Corinne; Liguori, Sandrine; Burucoa, Christophe; Couetdic, Gérard; Doucet-Populaire, Florence; Ferroni, Agnès; Papin-Gibaud, Sophie; Grattard, Florence; Réglier-Poupet, Hélène; Raymond, Josette; Soler, Catherine; Bouchet, Sylvie; Charreau, Sandrine; Couzon, Brigitte; Leymarie, Isabelle; Tavares, Nicole; Choux, Mathilde; Bingen, Edouard; Bonacorsi, Stéphane

    2009-10-01

    With the support of a ministerial program for innovative and expensive technologies, dedicated to the economic evaluation of laboratory diagnosis of pertussis by real-time PCR, external quality assessment for real-time IS481 PCR was carried out. Coordinated by the National Centre of Reference of Pertussis and other Bordetelloses (NCR), this study aimed to harmonize and to assess the performances of eight participating microbiology hospital laboratories throughout the French territory. Between January 2006 and February 2007, 10 proficiency panels were sent by the NCR (ascending proficiency program), representing a total of 49 samples and including eight panels to analyze and evaluate the global sensitivity and specificity of real-time PCR, one to assess the limit of detection, and one to evaluate nucleic acid extraction methods. As part of the descending proficiency program, extracted DNA from clinical samples was sent by the eight participating laboratories in different panels and analyzed by the NCR. In the ascending proficiency analysis, the sensitivity and specificity of the real-time PCR methods were 92.2% and 94.3%, respectively. The limit of detection of the different methods ranged between 0.1 and 1 fg/microl (0.2 to 2 CFU/microl). The nucleic acid extraction methods showed similar performances. During the descending proficiency analysis, performed with 126 samples, the result of the NCR for 15 samples (11.9%) was discordant with the result obtained by the source laboratory. Despite several initial differences, harmonization was easy and performances were homogeneous. However, the risk of false-positive results remains quite high, and we strongly recommend establishment of uniform quality control procedures performed regularly.

  1. Establishment of national laboratory standards in public and private hospital laboratories.

    PubMed

    Anjarani, Soghra; Safadel, Nooshafarin; Dahim, Parisa; Amini, Rana; Mahdavi, Saeed; Mirab Samiee, Siamak

    2013-01-01

    In September 2007 national standard manual was finalized and officially announced as the minimal quality requirements for all medical laboratories in the country. Apart from auditing laboratories, Reference Health Laboratory has performed benchmarking auditing of medical laboratory network (surveys) in provinces. 12(th) benchmarks performed in Tehran and Alborz provinces, Iran in 2010 in three stages. We tried to compare different processes, their quality and accordance with national standard measures between public and private hospital laboratories. The assessment tool was a standardized checklist consists of 164 questions. Analyzing process show although in most cases implementing the standard requirements are more prominent in private laboratories, there is still a long way to complete fulfillment of requirements, and it takes a lot of effort. Differences between laboratories in public and private sectors especially in laboratory personnel and management process are significant. Probably lack of motivation, plays a key role in obtaining less desirable results in laboratories in public sectors.

  2. Establishment of National Laboratory Standards in Public and Private Hospital Laboratories

    PubMed Central

    ANJARANI, Soghra; SAFADEL, Nooshafarin; DAHIM, Parisa; AMINI, Rana; MAHDAVI, Saeed; MIRAB SAMIEE, Siamak

    2013-01-01

    In September 2007 national standard manual was finalized and officially announced as the minimal quality requirements for all medical laboratories in the country. Apart from auditing laboratories, Reference Health Laboratory has performed benchmarking auditing of medical laboratory network (surveys) in provinces. 12th benchmarks performed in Tehran and Alborz provinces, Iran in 2010 in three stages. We tried to compare different processes, their quality and accordance with national standard measures between public and private hospital laboratories. The assessment tool was a standardized checklist consists of 164 questions. Analyzing process show although in most cases implementing the standard requirements are more prominent in private laboratories, there is still a long way to complete fulfillment of requirements, and it takes a lot of effort. Differences between laboratories in public and private sectors especially in laboratory personnel and management process are significant. Probably lack of motivation, plays a key role in obtaining less desirable results in laboratories in public sectors. PMID:23514840

  3. BROOKHAVEN NATIONAL LABORATORY WILDLIFE MANAGEMENT PLAN.

    SciTech Connect

    NAIDU,J.R.

    2002-10-22

    The purpose of the Wildlife Management Plan (WMP) is to promote stewardship of the natural resources found at the Brookhaven National Laboratory (BNL), and to integrate their protection with pursuit of the Laboratory's mission.

  4. NNSA Master Asset Map - Sandia National Laboratories

    SciTech Connect

    Billie, Gepetta S.

    2017-01-01

    This report gives information on the following topics related to Sandia National Laboratories: site leadership's vision, condition, footprint management, major gaps and risks, and proposed investment plan.

  5. DATA RECOVERY EFFORTS AT IDAHO NATIONAL LABORATORY, OAK RIDGE NATIONAL LABORATORY, AND SAVANNAH RIVER NATIONAL LABORATORY

    SciTech Connect

    Richard Metcalf; Saleem Salaymeh; Michael Ehinger

    2010-07-01

    Abstract was already submitted. Could not find the previous number. Would be fine with attaching/update of old number. Abstract Below: Modern nuclear facilities will have significant process monitoring capability for their operators. These systems will also be used for domestic safeguards applications, which has led to research over new diversion-detection algorithms. Curiously missing from these efforts are verification and validation data sets. A tri-laboratory project to locate the existing data sets and recover their data has yielded three major potential sources of data. The first is recovery of the process monitoring data of the Idaho Chemical Processing Plant, which now has a distributable package for algorithm developers. The second data set is extensive sampling and process data from Savannah River National Laboratory’s F- and H-canyon sites. Finally, high fidelity data from the start-up tests at the Barnwell Reprocessing Facility is in recovery. This paper details the data sets and compares their relative attributes.

  6. Transient dynamics capability at Sandia National Laboratories

    NASA Technical Reports Server (NTRS)

    Attaway, Steven W.; Biffle, Johnny H.; Sjaardema, G. D.; Heinstein, M. W.; Schoof, L. A.

    1993-01-01

    A brief overview of the transient dynamics capabilities at Sandia National Laboratories, with an emphasis on recent new developments and current research is presented. In addition, the Sandia National Laboratories (SNL) Engineering Analysis Code Access System (SEACAS), which is a collection of structural and thermal codes and utilities used by analysts at SNL, is described. The SEACAS system includes pre- and post-processing codes, analysis codes, database translation codes, support libraries, Unix shell scripts for execution, and an installation system. SEACAS is used at SNL on a daily basis as a production, research, and development system for the engineering analysts and code developers. Over the past year, approximately 190 days of CPU time were used by SEACAS codes on jobs running from a few seconds up to two and one-half days of CPU time. SEACAS is running on several different systems at SNL including Cray Unicos, Hewlett Packard PH-UX, Digital Equipment Ultrix, and Sun SunOS. An overview of SEACAS, including a short description of the codes in the system, are presented. Abstracts and references for the codes are listed at the end of the report.

  7. Push technology at Argonne National Laboratory.

    SciTech Connect

    Noel, R. E.; Woell, Y. N.

    1999-04-06

    Selective dissemination of information (SDI) services, also referred to as current awareness searches, are usually provided by periodically running computer programs (personal profiles) against a cumulative database or databases. This concept of pushing relevant content to users has long been integral to librarianship. Librarians traditionally turned to information companies to implement these searches for their users in business, academia, and the science community. This paper describes how a push technology was implemented on a large scale for scientists and engineers at Argonne National Laboratory, explains some of the challenges to designers/maintainers, and identifies the positive effects that SDI seems to be having on users. Argonne purchases the Institute for Scientific Information (ISI) Current Contents data (all subject areas except Humanities), and scientists no longer need to turn to outside companies for reliable SDI service. Argonne's database and its customized services are known as ACCESS (Argonne-University of Chicago Current Contents Electronic Search Service).

  8. Structural health monitoring activities at National Laboratories

    SciTech Connect

    Farrar, C.R.; Doebling, S.W.; James, G.H.; Simmermacher, T.

    1997-09-01

    Sandia National Laboratories and Los Alamos National Laboratory have on-going programs to assess damage in structures and mechanical systems from changes in their dynamic characteristics. This paper provides a summary of how both institutes became involved with this technology, their experience in this field and the directions that their research in this area will be taking in the future.

  9. Modernizing the National Spatial Reference System

    NASA Astrophysics Data System (ADS)

    Smith, D. A.

    2016-12-01

    The National Spatial Reference System (NSRS) is that system of datums, reference frames, shorelines, software and standards which serve the entire federal civilian geospatial community. It is the mission of the National Geodetic Survey (NGS) to define, maintain and provide access to the NSRS. Currently the NSRS contains three geometric reference frames (NAD 83(2011), NAD 83(PA11) and NAD 83(MA11)), one dynamic height datum (IGLD 85) and 6 vertical datums (NAVD 88, PRVD02, ASVD02, NMVD03, GUVD04, VIVD09). All of these datums are built on aging technology and contain systematic errors that grow more noticeable as access to accurate positioning becomes more widespread. It was determined by NGS in 2007 that this was not sustainable and as such, all datums and reference frames are scheduled to be replaced in 2022. [At the time of this abstract, the exact names of the replacements are being finalized and are expected to be announced by the AGU fall meeting.] Replacing the official datums and reference frames requires a carefully coordinated effort of dozens of interrelated technical projects spanning years (over a decade in some cases) and involving a majority of NGS employees. This talk will cover the plans thus far, projects completed, projects underway and will summarize the NSRS as it is expected to look and be accessed in 2022 and beyond.

  10. Should the national laboratories exist in 2005?

    SciTech Connect

    Gillman, K.

    1995-12-31

    National laboratories are sometimes defined as all government related laboratories which runs into the hundreds. However, the Department of Defense (DOD), Department of Energy (DOE) and National Aeronautical and Space Administration (NASA) laboratories dominate the federal research, development, testing and evaluation establishment. Funding data for these major research establishments are provided. Each of these agencies has conducted a review of its own laboratories to rate their effectiveness and comparative advantage in responding to five areas of national need. National need was defined as: fundamental science, national security, technology development for industrial competitiveness, environmental protection and clean-up, and space exploration and aeronautics. The author examines the rationales and justification set forth by the various laboratory complexes for their continued existence.

  11. Establishing an enteric bacteria reference laboratory in Sierra Leone.

    PubMed

    Chattaway, Marie Anne; Kamara, Abdul; Rhodes, Fay; Kaffeta, Konneh; Jambai, Amara; Alemu, Wondimagegnehu; Islam, Mohammed Sirajul; Freeman, Molly M; Welfare, William; Harding, Doris; Samba, Ahmed F; Abu, Musu; Kamanda, Sylvester; Grant, Kathie; Jenkins, Claire; Nair, Satheesh; Connell, Steve; Siorvanes, Lisa; Desai, Sarika; Allen, Collette; Frost, Margaret; Hughes, Daniel; Jeffrey, Zonya; Gill, Noel; Salter, Mark

    2014-06-09

    In 2012, Sierra Leone experienced its worst cholera outbreak in over 15 years affecting 12 of the country's 13 districts. With limited diagnostic capability, particularly in bacterial culture, the cholera outbreak was initially confirmed by microbiological testing of clinical specimens outside of Sierra Leone. During 2012 - 2013, in direct response to the lack of diagnostic microbiology facilities, and to assist in investigating and monitoring the cholera outbreak, diagnostic and reference services were established in Sierra Leone at the Central Public Health Reference Laboratory focusing specifically on isolating and identifying Vibrio cholerae and other enteric bacterial pathogens. Sierra Leone is now capable of confirming cholera cases by reference laboratory testing.

  12. Comparison of two alternative microdilution procedures with the National Committee for Clinical Laboratory Standards reference macrodilution method M27-P for in vitro testing of fluconazole-resistant and -susceptible isolates of Candida albicans.

    PubMed Central

    Espinel-Ingroff, A; Rodríguez-Tudela, J L; Martínez-Suárez, J V

    1995-01-01

    The National Committee for Clinical Laboratory Standards has proposed a reference broth macrodilution method for in vitro antifungal susceptibility testing of yeasts (the M27-P method). This method is cumbersome and time-consuming and includes MIC endpoint determination by the visual and subjective inspection of growth inhibition after 48 h of incubation. Two alternative microdilution procedures for MIC endpoint determination, a spectrophotometric MIC endpoint test that evaluates 80% growth inhibition by the drug and a colorimetric method with an oxidation-reduction indicator (Alamar Blue), were compared with the M27-P method for fluconazole susceptibility testing of 45 susceptible and resistant isolates of Candida albicans. The spectrophotometric method was performed with RPMI 1640 medium with 2% glucose, and the other two tests were performed with plain RPMI 1640 medium. All tests were incubated at 35 degrees C. Excellent agreement was demonstrated between the M27-P method and both 24-h microdilution tests (97.7%) as well as between the two microdilution tests (95.5%). Also, there was agreement in the detection in vivo of fluconazole resistance by the three methods. These preliminary data indicate that both microdilution methods may serve as less subjective alternatives to the M27-P method for the determination of fluconazole MIC endpoints. PMID:8586692

  13. National reference doses for dental cephalometric radiography.

    PubMed

    Holroyd, J R

    2011-12-01

    Diagnostic reference levels (DRLs) are an important tool in the optimisation of clinical radiography. Although national DRLs are provided for many diagnostic procedures including dental intra-oral radiography, there are currently no national DRLs set for cephalometric radiography. In the absence of formal national DRLs, the Health Protection Agency (HPA) has previously published National Reference Doses (NRDs) covering a wide range of diagnostic X-ray examinations. The aim of this study was to determine provisional NRDs for cephalometric radiography. Measurements made by the Dental X-ray Protection Service (DXPS) of the HPA, as part of the cephalometric X-ray equipment testing service provided to dentists and dental trade companies throughout the UK, were used to derive provisional NRDs. Dose-area product measurements were made on 42 X-ray sets. Third quartile dose-area product values for adult and child lateral cephalometric radiography were found to be 41 mGy cm² and 25 mGy cm², respectively, with individual measurements ranging from 3 mGy cm² to 108 mGy cm². This report proposes provisional NRDs of 40 mGy cm² and 25 mGy cm² for adult and child lateral cephalometric radiographs, respectively; these doses could be considered by employers when establishing their local DRLs.

  14. Expanded recycling at Los Alamos National Laboratory

    SciTech Connect

    Betschart, J.F.; Malinauskas, L.; Burns, M.

    1996-07-01

    The Pollution Prevention Program Office has increased recycling activities, reuse, and options to reduce the solid waste streams through streamlining efforts that applied best management practices. The program has prioritized efforts based on volume and economic considerations and has greatly increased Los Alamos National Laboratory`s (LANL`s) recycle volumes. The Pollution Prevention Program established and chairs a Solid Waste Management Solutions Group to specifically address and solve problems in nonradioactive, Resource Conservation and Recovery Act (RCRA), state-regulated, and sanitary and industrial waste streams (henceforth referred to as sanitary waste in this paper). By identifying materials with recycling potential, identifying best management practices and pathways to return materials for reuse, and introducing the concept and practice of {open_quotes}asset management,{open_quotes} the Group will divert much of the current waste stream from disposal. This Group is developing procedures, agreements, and contracts to stage, collect, sort, segregate, transport and process materials, and is also garnering support for the program through the involvement of upper management, facility managers, and generators.

  15. Transport equations of electrodiffusion processes in the laboratory reference frame.

    PubMed

    Garrido, Javier

    2006-02-23

    The transport equations of electrodiffusion processes use three reference frames for defining the fluxes: Fick's reference in diffusion, solvent-fixed reference in transference numbers, and laboratory fluxes in electric conductivity. The convenience of using only one reference frame is analyzed here from the point of view of the thermodynamics of irreversible processes. A relation between the fluxes of ions and solvent and the electric current density is deduced first from a mass and volume balance. This is then used to show that (i) the laboratory and Fick's diffusion coefficients are identical and (ii) the transference numbers of both the solvent and the ion in the laboratory reference frame are related. Finally, four experimental methods for the measurement of ion transference numbers are analyzed critically. New expressions for evaluating transference numbers for the moving boundary method and the chronopotentiometry technique are deduced. It is concluded that the ion transport equation in the laboratory reference frame plays a key role in the description of electrodiffusion processes.

  16. Nonvolatile memory technology at Sandia National Laboratories

    SciTech Connect

    Sokel, R.J.; Dodson, W.H.; Knoll, M.G.

    1981-01-01

    The nonvolatile memory program at Sandia National Laboratories is discussed with special emphasis on the relationship between technology and design. Three different MNOS technologies which have been developed for EAROM, RAM, and EEPROM applications are considered.

  17. Metamaterials program at Sandia National Laboratories.

    SciTech Connect

    McCormick, Frederick Bossert

    2010-10-01

    Sandia National Laboratories Metamaterial Science and Technology Program has developed novel HPC-based design tools, wafer scale 3D fabrication processes, and characterization tools to enable thermal IR optical metamaterial application studies.

  18. Photovoltaic technology development at Sandia National Laboratories

    SciTech Connect

    1981-12-31

    This report describes the following investigations being pursued under photovoltaic technology development at Sandia National Laboratories: photovoltaic systems technology; concentrator technology; concentrator arrays and tracking structures; concentrator solar cell development; system engineering; subsystem development; and test and applications.

  19. Job cuts loom at National Physical Laboratory

    NASA Astrophysics Data System (ADS)

    Extance, Andy

    2016-09-01

    The UK's National Physical Laboratory (NPL) - the country's standards lab - is consulting on making up to 50 compulsory redundancies as it prepares to shift its research priorities towards quantum technologies and big data.

  20. Department of Energy national laboratories

    SciTech Connect

    Trivelpiece, A.W.

    1990-01-01

    This paper is a transcript of the testimony of Alvin W. Travelpiece before the Congressional Subcommittee on Research and Development. Emphasis is placed on the importance of funding nuclear programs to assure national well-being; and, past accomplishments in the nuclear programs are reviewed. (FSD)

  1. The Future of the National Laboratories

    SciTech Connect

    Hartley, D.

    1997-12-31

    The policy debate that has surrounded the national laboratories of the Department of Energy since the end of the Cold War has been very confusing. Initially, with the passage of the National Competitiveness Technology Transfer Act of 1989, the laboratories were encouraged to form cooperative arrangements with industry to maintain their technology base and give a boost for U.S. industrial competitiveness. But in the 104th Congress, technology transfer programs were severely constrained.

  2. Inverter testing at Sandia National Laboratories

    SciTech Connect

    Ginn, J.W.; Bonn, R.H.; Sittler, G.

    1997-04-01

    Inverters are key building blocks of photovoltaic (PV) systems that produce ac power. The balance of systems (BOS) portion of a PV system can account for up to 50% of the system cost, and its reliable operation is essential for a successful PV system. As part of its BOS program, Sandia National Laboratories (SNL) maintains a laboratory wherein accurate electrical measurements of power systems can be made under a variety of conditions. This paper outlines the work that is done in that laboratory.

  3. DNA-Based Methods in the Immunohematology Reference Laboratory

    PubMed Central

    Denomme, Gregory A

    2010-01-01

    Although hemagglutination serves the immunohematology reference laboratory well, when used alone, it has limited capability to resolve complex problems. This overview discusses how molecular approaches can be used in the immunohematology reference laboratory. In order to apply molecular approaches to immunohematology, knowledge of genes, DNA-based methods, and the molecular bases of blood groups are required. When applied correctly, DNA-based methods can predict blood groups to resolve ABO/Rh discrepancies, identify variant alleles, and screen donors for antigen-negative units. DNA-based testing in immunohematology is a valuable tool used to resolve blood group incompatibilities and to support patients in their transfusion needs. PMID:21257350

  4. [Determining and verifying reference intervals in clinical laboratories].

    PubMed

    Henny, Joseph

    2011-01-01

    Based on the original recommendation of the Expert Panel on the Theory of Reference Values of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC-LM), updated guidelines were recently published under the auspices of the IFCC-LM and the Clinical and Laboratory Standards Institute (CLSI). This article summarises these new proposals: (1) defining more precisely the terminology, which is often confusing, noticeably concerning the terms of reference limits and decision limits; (2) showing the different steps for determining reference limits according to the original procedure and the conditions which should be respected and (3) proposing a simple methodology allowing to the Clinical Laboratories to satisfy the needs of the Regulation and Standards. The updated document proposes to verify if published reference limits are applicable to the Laboratory involved. Finally the strengths and limits of the revised recommendations (noticeably the selection of the reference population, the maintenance of the analytical quality, the choice of the statistical methodology, etc.) will be briefly discussed.

  5. Automated production of an on-line laboratory reference manual from a laboratory information system.

    PubMed

    Bennett, Sterling T; Kern, Dale A

    2002-04-01

    Laboratories provide information beyond test results, including information related to patient preparation, specimen collection and handling, test methodology, test availability, and interpretation of results. Most laboratories publish reference manuals to distribute this information to clients, while relying on the laboratory information system to provide this information to laboratory staff. Maintaining duplicate sources of information is expensive and error-prone, and printed materials become rapidly outdated. We developed a process to automate the production of a web-based reference manual directly from the laboratory information system, using a combination of MUMPS programs and HTML templates. We now focus our resources to assure that the laboratory information system database is accurate and complete, and then with minimal additional effort or expense produce an up-to-date on-line reference manual. We are therefore able to provide better sources of information in a sustainable manner.

  6. Lawrence Livermore National Laboratory Environmental Report 2010

    SciTech Connect

    Jones, H E; Bertoldo, N A; Campbell, C G; Cerruti, S J; Coty, J D; Dibley, V R; Doman, J L; Grayson, A R; MacQueen, D H; Wegrecki, A M; Armstrong, D H; Brigdon, S L; Heidecker, K R; Hollister, R K; Khan, H N; Lee, G S; Nelson, J C; Paterson, L E; Salvo, V J; Schwartz, W W; Terusaki, S H; Wilson, K R; Woods, J M; Yimbo, P O; Gallegos, G M; Terrill, A A; Revelli, M A; Rosene, C A; Blake, R G; Woollett, J S; Kumamoto, G

    2011-09-14

    The purposes of the Lawrence Livermore National Laboratory Environmental Report 2010 are to record Lawrence Livermore National Laboratory's (LLNL's) compliance with environmental standards and requirements, describe LLNL's environmental protection and remediation programs, and present the results of environmental monitoring at the two LLNL sites - the Livermore site and Site 300. The report is prepared for the U.S. Department of Energy (DOE) by LLNL's Environmental Protection Department. Submittal of the report satisfies requirements under DOE Order 231.1A, Environmental Safety and Health Reporting, and DOE Order 5400.5, Radiation Protection of the Public and Environment. The report is distributed electronically and is available at https://saer.llnl.gov/, the website for the LLNL annual environmental report. Previous LLNL annual environmental reports beginning in 1994 are also on the website. Some references in the electronic report text are underlined, which indicates that they are clickable links. Clicking on one of these links will open the related document, data workbook, or website that it refers to. The report begins with an executive summary, which provides the purpose of the report and an overview of LLNL's compliance and monitoring results. The first three chapters provide background information: Chapter 1 is an overview of the location, meteorology, and hydrogeology of the two LLNL sites; Chapter 2 is a summary of LLNL's compliance with environmental regulations; and Chapter 3 is a description of LLNL's environmental programs with an emphasis on the Environmental Management System including pollution prevention. The majority of the report covers LLNL's environmental monitoring programs and monitoring data for 2010: effluent and ambient air (Chapter 4); waters, including wastewater, storm water runoff, surface water, rain, and groundwater (Chapter 5); and terrestrial, including soil, sediment, vegetation, foodstuff, ambient radiation, and special status

  7. The future of the national laboratories

    SciTech Connect

    Cohen, L.R.; Noll, R.G.

    1996-11-12

    The end of the Cold War has called into question the activities of the national laboratories and, more generally, the level of support now given to federal intramural research in the United States. This paper seeks to analyze the potential role of the laboratories, with particular attention to the possibility, on the one hand, of integrating private technology development into the laboratory`s menu of activities and, on the other hand, of outsourcing traditional mission activities. We review the economic efficiency arguments for intramural research and the political conditions that are likely to constrain the activities of the laboratories, and analyze the early history of programs intended to promote new technology via cooperative agreements between the laboratories and private industry. Our analysis suggests that the laboratories are likely to shrink considerably in size, and that the federal government faces a significant problem in deciding how to organize a downsizing of the federal research establishment. 20 refs., 1 fig., 4 tabs.

  8. Brookhaven highlights - Brookhaven National Laboratory 1995

    SciTech Connect

    1996-09-01

    This report highlights research conducted at Brookhaven National Laboratory in the following areas: alternating gradient synchrotron; physics; biology; national synchrotron light source; department of applied science; medical; chemistry; department of advanced technology; reactor; safety and environmental protection; instrumentation; and computing and communications.

  9. The USDA Forest Service National Seed Laboratory

    Treesearch

    Robert P. Karrfalt

    2006-01-01

    The USDA Forest Service National Seed Laboratory has provided seed technology services to the forest and conservation seed and nursery industry for more than 50 years. This paper briefly traces the lab’s evolution from a regional facility concerned principally with southern pines to its newest mission as a national facility working with all native U.S. plants and...

  10. Effluent-Monitoring Procedures: Basic Laboratory Skills. Student Reference Manual.

    ERIC Educational Resources Information Center

    Engel, William T.; And Others

    This is one of several short-term courses developed to assist in the training of waste water treatment plant operational personnel in the tests, measurements, and report preparation required for compliance with their NPDES Permits. This Student Reference Manual provides a review of basic mathematics as it applies to the chemical laboratory. The…

  11. Sandia National Laboratories Education Outreach Activities

    SciTech Connect

    Dawes, William R. Jr.

    1999-08-26

    The US Department of Energy and its national laboratories are a major employer of scientists and engineers and consequently have a strong interest in the development and training of a qualified pool of employment candidates. For many years the DOE and its national laboratories have supported education activities devoted to increasing the number and quality of science and engineering graduates. This is part of the DOE mission because of the critical national need for scientists and engineers and the recognized deficiencies in the education system for science and mathematics training. Though funding support for such activities has waxed and waned, strong education programs have survived in spite of budget pressures. This paper reviews a few of the education programs presently supported at Sandia by the Science and Technology Outreach Department. The US DOE Defense Programs Office and Sandia National Laboratories provide financial support for these education activities.

  12. Idaho National Laboratory Research & Development Impacts

    SciTech Connect

    Stricker, Nicole

    2015-01-01

    Technological advances that drive economic growth require both public and private investment. The U.S. Department of Energy’s national laboratories play a crucial role by conducting the type of research, testing and evaluation that is beyond the scope of regulators, academia or industry. Examples of such work from the past year can be found in these pages. Idaho National Laboratory’s engineering and applied science expertise helps deploy new technologies for nuclear energy, national security and new energy resources. Unique infrastructure, nuclear material inventory and vast expertise converge at INL, the nation’s nuclear energy laboratory. Productive partnerships with academia, industry and government agencies deliver high-impact outcomes. This edition of INL’s Impacts magazine highlights national and regional leadership efforts, growing capabilities, notable collaborations, and technology innovations. Please take a few minutes to learn more about the critical resources and transformative research at one of the nation’s premier applied science laboratories.

  13. National Environmental Policy Act (NEPA) compliance at Sandia National Laboratories/New Mexico (SNL/NM)

    SciTech Connect

    Wolff, T.A.; Hansen, R.P.

    1998-08-01

    This report on National Environmental Policy Act (NEPA) compliance at Sandia National Laboratories/New Mexico (SNL/NM) chronicles past and current compliance activities and includes a recommended strategy that can be implemented for continued improvement. This report provides a list of important references. Attachment 1 contains the table of contents for SAND95-1648, National Environmental Policy Act (NEPA) Compliance Guide Sandia National Laboratories (Hansen, 1995). Attachment 2 contains a list of published environmental assessments (EAs) and environmental impact statements (EISs) prepared by SNL/NM. Attachment 3 contains abstracts of NEPA compliance papers authored by SNL/NM and its contractors.

  14. Challenges of implementing Iranian national laboratory standards.

    PubMed

    Safadel, N; Dahim, P; Anjarani, S; Rahnamaye Farzami, M; Samiee, S Mirab; Amini, R; Farsi, Sh; Mahdavi, S; Khodaverdian, K; Rashed Marandi, F

    2013-01-01

    After four years of publishing the Iranian National Laboratory Standard and following a strategic plan to implement its requirements, it was decided to review the taken actions, evaluating the achievements and the failures, as well as analyzing the gaps and planning the interventional activities to resolve the problems. A thorough evaluation revealed that the progress of implementation process varies considerably in different provinces, as well as in laboratories in different public and private sectors. Diversity and heterogeneousity of laboratories throughout the country is one of unresolvable problems. Although we encounter shortage of resources in the country, improper allocation or distribution of resources and budgets make the problems more complicated. Inadequacy of academic training in laboratory sciences has resulted in necessity of holding comprehensive post-graduate training courses. Revising academic curriculum of laboratory sciences could be mostly helpful, moreover there should be organized, training courses with pre-determined practical topics. providing specific technical guidelines, to clarify the required technical details could temporarily fill the training gaps of laboratory staff. Inadequate number of competent auditors was one of the difficulties in universities. Another important challenge returns to laboratory equipment, developing the national controlling system to manage the laboratory equipment in terms of quality and accessibility has been planned in RHL. At last cultural problems and resistance to change are main obstacles that have reduced the pace of standardization, it needs to rationalize the necessity of establishing laboratory standards for all stakeholders.

  15. Creating the laboratory`s future; A strategy for Lawrence Livermore National Laboratory

    SciTech Connect

    1997-09-01

    ``Creating The Laboratory`s Future`` describes Livermore`s roles and responsibilities as a Department of Energy (DOE) national laboratory and sets the foundation for decisions about the Laboratory`s programs and operations. It summarizes Livermore`s near-term strategy, which builds on recent Lab achievements and world events affecting their future. It also discusses their programmatic and operational emphases and highlights program areas that the authors believe can grow through application of Lab science and technology. Creating the Laboratory`s Future reflects their very strong focus on national security, important changes in the character of their national security work, major efforts are under way to overhaul their administrative and operational systems, and the continuing challenge of achieving national consensus on the role of the government in energy, environment, and the biosciences.

  16. National Weather Service Forecast Reference Evapotranspiration

    NASA Astrophysics Data System (ADS)

    Osborne, H. D.; Palmer, C. K.; Krone-Davis, P.; Melton, F. S.; Hobbins, M.

    2013-12-01

    The National Weather Service (NWS), Weather Forecasting Offices (WFOs) are producing daily reference evapotranspiration (ETrc) forecasts or FRET across the Western Region and in other selected locations since 2009, using the Penman - Monteith Reference Evapotranspiration equation for a short canopy (12 cm grasses), adopted by the Environmental Water Resources Institute of the American Society of Civil Engineers (ASCE-EWRI, 2004). The sensitivity of these daily calculations to fluctuations in temperatures, humidity, winds, and sky cover allows forecasters with knowledge of local terrain and weather patterns to better forecast in the ETrc inputs. The daily FRET product then evolved into a suite of products, including a weekly ETrc forecast for better water planning and a tabular point forecast for easy ingest into local water management-models. The ETrc forecast product suite allows water managers, the agricultural community, and the public to make more informed water-use decisions. These products permit operational planning, especially with the impending drought across much of the West. For example, the California Department of Water Resources not only ingests the FRET into their soil moisture models, but uses the FRET calculations when determining the reservoir releases in the Sacramento and American Rivers. We will also focus on the expansion of FRET verification, which compares the daily FRET to the observations of ETo from the California Irrigation Management Information System (CIMIS) across California's Central Valley for the 2012 water year.

  17. ORNL (Oak Ridge National Laboratory) 89

    SciTech Connect

    Anderson, T.D.; Appleton, B.R.; Jefferson, J.W.; Merriman, J.R.; Mynatt, F.R.; Richmond, C.R.; Rosenthal, M.W.

    1989-01-01

    This is the inaugural issues of an annual publication about the Oak Ridge National Laboratory. Here you will find a brief overview of ORNL, a sampling of our recent research achievements, and a glimpse of the directions we want to take over the next 15 years. A major purpose of ornl 89 is to provide the staff with a sketch of the character and dynamics of the Laboratory.

  18. ISO 14001 IMPLEMENTATION AT A NATIONAL LABORATORY.

    SciTech Connect

    BRIGGS,S.L.K.

    2001-06-01

    After a tumultuous year discovering serious lapses in environment, safety and health management at Brookhaven National Laboratory, the Department of Energy established a new management contract. It called for implementation of an IS0 14001 Environmental Management System and registration of key facilities. Brookhaven Science Associates, the managing contractor for the Laboratory, designed and developed a three-year project to change culture and achieve the goals of the contract. The focus of its efforts were to use IS0 14001 to integrate environmental stewardship into all facets of the Laboratory's mission, and manage its programs in a manner that protected the ecosystem and public health. A large multidisciplinary National Laboratory with over 3,000 employees and 4,000 visiting scientists annually posed significant challenges for IS0 14001 implementation. Activities with environmental impacts varied from regulated industrial waste generation, to soil activation from particle accelerator operations, to radioactive groundwater contamination from research reactors. A project management approach was taken to ensure project completion on schedule and within budget. The major work units for the Environmental Management System Project were as follows: Institutional EMS Program Requirements, Communications, Training, Laboratory-wide Implementation, and Program Assessments. To minimize costs and incorporate lessons learned before full-scale deployment throughout the Laboratory, a pilot process was employed at three facilities. Brookhaven National Laboratory has completed its second year of the project in the summer of 2000, successfully registering nine facilities and self-declaring conformance in all remaining facilities. Project controls, including tracking and reporting progress against a model, have been critical to the successful implementation. Costs summaries are lower than initial estimates, but as expected legal requirements, training, and assessments are key cost

  19. ISO 14001 IMPLEMENTATION AT A NATIONAL LABORATORY.

    SciTech Connect

    BRIGGS,S.L.K.

    2001-06-01

    After a tumultuous year discovering serious lapses in environment, safety and health management at Brookhaven National Laboratory, the Department of Energy established a new management contract. It called for implementation of an IS0 14001 Environmental Management System and registration of key facilities. Brookhaven Science Associates, the managing contractor for the Laboratory, designed and developed a three-year project to change culture and achieve the goals of the contract. The focus of its efforts were to use IS0 14001 to integrate environmental stewardship into all facets of the Laboratory's mission, and manage its programs in a manner that protected the ecosystem and public health. A large multidisciplinary National Laboratory with over 3,000 employees and 4,000 visiting scientists annually posed significant challenges for IS0 14001 implementation. Activities with environmental impacts varied from regulated industrial waste generation, to soil activation from particle accelerator operations, to radioactive groundwater contamination from research reactors. A project management approach was taken to ensure project completion on schedule and within budget. The major work units for the Environmental Management System Project were as follows: Institutional EMS Program Requirements, Communications, Training, Laboratory-wide Implementation, and Program Assessments. To minimize costs and incorporate lessons learned before full-scale deployment throughout the Laboratory, a pilot process was employed at three facilities. Brookhaven National Laboratory has completed its second year of the project in the summer of 2000, successfully registering nine facilities and self-declaring conformance in all remaining facilities. Project controls, including tracking and reporting progress against a model, have been critical to the successful implementation. Costs summaries are lower than initial estimates, but as expected legal requirements, training, and assessments are key cost

  20. Microsystem technology development at Sandia National Laboratories

    SciTech Connect

    Smith, J.H.

    1995-11-01

    An overview of the major sensor and actuator projects using the micromachining capabilities of the Microelectronics Development Laboratory at Sandia National Laboratories is presented. Development efforts are underway for a variety of surface micromachined sensors and actuators. A technology that embeds micromechanical devices below the surface of the wafer prior to microelectronics fabrication has also been developed for integrating microelectronics with surface micromachined micromechanical devices.

  1. Sandia National Laboratories: The First Fifty Years

    SciTech Connect

    MORA,CARL J.

    1999-11-03

    On Nov. 1, 1999, Sandia National Laboratories celebrates its 50th birthday. Although Sandia has its roots in the World War II-era Manhattan Project, Sandia began operating as a separate nuclear weapons engineering laboratory under the management of AT&T on Nov. 1, 1949. Today the lab employs more than 7,000 people at its two sites in Albuquerque and Livermore, California, and has research and development missions in national security, energy and environmental technologies, and U.S. economic competitiveness. Lockheed Martin Corporation operates Sandia for the US. Department of Energy.

  2. National Water Quality Laboratory - A Profile

    USGS Publications Warehouse

    Raese, Jon W.

    2001-01-01

    The U.S. Geological Survey (USGS) National Water Quality Laboratory (NWQL) is a full-service laboratory that specializes in environmental analytical chemistry. The NWQL's primary mission is to support USGS programs requiring environmental analyses that provide consistent methodology for national assessment and trends analysis. The NWQL provides the following: high-quality chemical data; consistent, published, state-of-the-art methodology; extremely low-detection levels; high-volume capability; biological unit for identifying benthic invertebrates; quality assurance for determining long-term water-quality trends; and a professional staff.

  3. LDRD Highlights at the National Laboratories

    SciTech Connect

    Alayat, R. A.

    2016-10-10

    To meet the nation’s critical challenges, the Department of Energy (DOE) national laboratories have always pushed the boundaries of science, technology, and engineering. The Atomic Energy Act of 1954 provided the basis for these laboratories to engage in the cutting edge of science and technology and respond to technological surprises, while retaining the best scientific and technological minds. To help re-energize this commitment, in 1991 the U.S. Congress authorized the national laboratories to devote a relatively small percentage of their budget to creative and innovative work that serves to maintain their vitality in disciplines relevant to DOE missions. Since then, this effort has been formally called the Laboratory Directed Research and Development (LDRD) Program. LDRD has been an essential mechanism to enable the laboratories to address DOE’s current and future missions with leading-edge research proposed independently by laboratory technical staff, evaluated through expert peer-review committees, and funded by the individual laboratories consistent with the authorizing legislation and the DOE LDRD Order 413.2C.

  4. National Nutrition Education Clearing House Reference List, General Teacher References.

    ERIC Educational Resources Information Center

    National Nutrition Education Clearing House, Berkeley, CA.

    References applicable to both elementary and secondary levels, as well as background information of importance to teachers in the field of nutrition and nutrition education, are included in this bibliography. Although not a comprehensive list, resources include books, pamphlets, curriculum guides, bibliographies, newsletters, article reprints, and…

  5. Reference materials and reference measurement systems in laboratory medicine. Harmonization of nomenclature and definitions in reference measurement systems.

    PubMed

    Dybkaer, R

    1995-12-01

    Reliability of clinical laboratory results is obtained through quality assurance in both their production and transmission. The former involves a reference measurement system of reference materials and reference measurement procedures with metrological and statistical verification of results. The latter requires that sender and receiver have access to a common terminology. Thus, two data banks are required. A plurilingual systematic vocabulary related to the reference measurement system, giving concepts with terms and definitions concerning measurement standards, reference measurement procedures, internal quality control, external quality assessment, probability and statistics-mainly based on existing authoritative publications. The material should be processed by standard scientific terminological procedure and offered to pertinent organizations and specialists for comment before finalization and authorization. A multilingual collection of systematic names for properties examined by the branches of Laboratory Medicine, such as clinical chemistry, clinical immunology, clinical microbiology, clinical pharmacology, haematology and blood banking, and histochemistry and cytology. The database should function as a reference to consultation and as a link in the transmission of data between local laboratory "dialects". This should be based on the ongoing comprehensive IUPAC/IFCC project for forming names in collaboration with relevant scientific organisations and area specialists. The relational data base including "run-time" software would be accessed by e-mail (gopher or other storage medium).

  6. Sandia National Laboratories focus issue: introduction.

    PubMed

    Boye, Robert

    2014-08-20

    For more than six decades, Sandia has provided the critical science and technology to address the nation's most challenging issues. Our original nuclear weapons mission has been complemented with work in defense systems, energy and climate, as well as international and homeland security. Our vision is to be a premier science and engineering laboratory for technology solutions to the most challenging problems that threaten peace and freedom for our nation and the globe.

  7. Mobile robotics research at Sandia National Laboratories

    SciTech Connect

    Morse, W.D.

    1998-09-01

    Sandia is a National Security Laboratory providing scientific and engineering solutions to meet national needs for both government and industry. As part of this mission, the Intelligent Systems and Robotics Center conducts research and development in robotics and intelligent machine technologies. An overview of Sandia`s mobile robotics research is provided. Recent achievements and future directions in the areas of coordinated mobile manipulation, small smart machines, world modeling, and special application robots are presented.

  8. Lawrence Livermore National Laboratory Summer Employment Summary

    SciTech Connect

    Wilson, A J

    2002-08-06

    This document will serve as a summary of my work activities as a summer employee for the Lawrence Livermore National Laboratory (LLNL). The intent of this document is to provide an overview of the National Ignition Facility (NIF) project, to explain the role of the department that I am working for, and to discuss my specific assigned tasks and their impact on the NIF project as a whole.

  9. Lawrence Livermore National Laboratory hot spot mobile laboratory

    SciTech Connect

    Buddemeier, B

    1999-08-27

    Gross alpha/beta/tritium liquid The Hot Spot Mobile Laboratory is an asset used to analyze samples (some high hazard) from the field. Field laboratories allow the quick turnaround of samples needed to establish weapon condition and hazard assessment for the protection of responders and the public. The Hot Spot Lab is configured to fly anywhere in the world and is staffed by expert scientists and technicians from Lawrence Livermore National Laboratory who perform similar functions in their routine jobs. The Hot Spot Team carries sample control kits to provide responding field teams with the procedures, tools, and equipment for sample collection and field measurements. High-hazard samples brought back from the field are prepared for analysis in HEPA-filtered gloveboxes staffed by technicians from LLNL's Plutonium Facility. The samples are passed on to the Mobile Laboratory which carries a variety of radiological and chemical analytical equipment in portable configuration for use in the field. Equipment and personnel can also deploy special assets to local hospitals or the field for detection of plutonium in a lung or wound. Quick assessment of personnel contamination is essential for time-critical medical intervention. In addition to pulling the trailer, the Hot Spot Truck also stores some of the equipment, consumables, and a PTO generator. The Hot Spot Laboratory has the capability to be self-sufficient for several weeks when deployed to determine Pu uptake.

  10. Biomedical engineering at Sandia National Laboratories

    NASA Astrophysics Data System (ADS)

    Zanner, Mary Ann

    1994-12-01

    The potential exists to reduce or control some aspects of the U.S. health care expenditure without compromising health care delivery by developing carefully selected technologies which impact favorably on the health care system. A focused effort to develop such technologies is underway at Sandia National Laboratories. As a DOE National Laboratory, Sandia possesses a wealth of engineering and scientific expertise that can be readily applied to this critical national need. Appropriate mechanisms currently exist to allow transfer of technology from the laboratory to the private sector. Sandia's Biomedical Engineering Initiative addresses the development of properly evaluated, cost-effective medical technologies through team collaborations with the medical community. Technology development is subjected to certain criteria including wide applicability, earlier diagnoses, increased efficiency, cost-effectiveness and dual-use. Examples of Sandia's medical technologies include a noninvasive blood glucose sensor, computer aided mammographic screening, noninvasive fetal oximetry and blood gas measurement, burn diagnostics and laser debridement, telerobotics and ultrasonic scanning for prosthetic devices. Sandia National Laboratories has the potential to aid in directing medical technology development efforts which emphasize health care needs, earlier diagnosis, cost containment and improvement of the quality of life.

  11. Introduction to the National Information Display Laboratory

    NASA Technical Reports Server (NTRS)

    Carlson, Curtis R.

    1992-01-01

    The goals of the National Information Display Laboratory (NIDL) are described in viewgraph form. The NIDL is a Center of Excellence in softcopy technology with the overall goal to develop new ways to satisfy government information needs through aggressive user support and the development of advanced technology. Government/industry/academia participation, standards development, and various display technologies are addressed.

  12. Applied programs at Brookhaven National Laboratory

    SciTech Connect

    Not Available

    1991-09-01

    This document overviews the areas of current research at Brookhaven National Laboratory. Technology transfer and the user facilities are discussed. Current topics are presented in the areas of applied physics, chemical science, material science, energy efficiency and conservation, environmental health and mathematics, biosystems and process science, oceanography, and nuclear energy. (GHH)

  13. Nuclear Forensics at Los Alamos National Laboratory

    SciTech Connect

    Podlesak, David W; Steiner, Robert E.; Burns, Carol J.; LaMont, Stephen P.; Tandon, Lav

    2012-08-09

    The overview of this presentation is: (1) Introduction to nonproliferation efforts; (2) Scope of activities at Los Alamos National Laboratory; (3) Facilities for radioanalytical work at LANL; (4) Radiochemical characterization capabilities; and (5) Bulk chemical and materials analysis capabilities. Some conclusions are: (1) Analytical chemistry measurements on plutonium and uranium matrices are critical to numerous defense and non-defense programs including safeguards accountancy verification measurements; (2) Los Alamos National Laboratory operates capable actinide analytical chemistry and material science laboratories suitable for nuclear material forensic characterization; (3) Actinide analytical chemistry uses numerous means to validate and independently verify that measurement data quality objectives are met; and (4) Numerous LANL nuclear facilities support the nuclear material handling, preparation, and analysis capabilities necessary to evaluate samples containing nearly any mass of an actinide (attogram to kilogram levels).

  14. U.S. Department of Energy Commercial Reference Building Models of the National Building Stock

    SciTech Connect

    Deru, M.; Field, K.; Studer, D.; Benne, K.; Griffith, B.; Torcellini, P.; Liu, B.; Halverson, M.; Winiarski, D.; Rosenberg, M.; Yazdanian, M.; Huang, J.; Crawley, D.

    2011-02-01

    The U.S. Department of Energy (DOE) Building Technologies Program has set the aggressive goal of producing marketable net-zero energy buildings by 2025. This goal will require collaboration between the DOE laboratories and the building industry. We developed standard or reference energy models for the most common commercial buildings to serve as starting points for energy efficiency research. These models represent fairly realistic buildings and typical construction practices. Fifteen commercial building types and one multifamily residential building were determined by consensus between DOE, the National Renewable Energy Laboratory, Pacific Northwest National Laboratory, and Lawrence Berkeley National Laboratory, and represent approximately two-thirds of the commercial building stock.

  15. The International Space Station: A National Laboratory

    NASA Technical Reports Server (NTRS)

    Giblin, Timothy W.

    2012-01-01

    After more than a decade of assembly missions and the end of the space shuttle program, the International Space Station (ISS) has reached assembly completion. With other visiting spacecraft now docking with the ISS on a regular basis, the orbiting outpost now serves as a National Laboratory to scientists back on Earth. The ISS has the ability to strengthen relationships between NASA, other Federal entities, higher educational institutions, and the private sector in the pursuit of national priorities for the advancement of science, technology, engineering, and mathematics. The ISS National Laboratory also opens new paths for the exploration and economic development of space. In this presentation we will explore the operation of the ISS and the realm of scientific research onboard that includes: (1) Human Research, (2) Biology & Biotechnology, (3) Physical & Material Sciences, (4) Technology, and (5) Earth & Space Science.

  16. Chemical research at Argonne National Laboratory

    SciTech Connect

    1997-04-01

    Argonne National Laboratory is a research and development laboratory located 25 miles southwest of Chicago, Illinois. It has more than 200 programs in basic and applied sciences and an Industrial Technology Development Center to help move its technologies to the industrial sector. At Argonne, basic energy research is supported by applied research in diverse areas such as biology and biomedicine, energy conservation, fossil and nuclear fuels, environmental science, and parallel computer architectures. These capabilities translate into technological expertise in energy production and use, advanced materials and manufacturing processes, and waste minimization and environmental remediation, which can be shared with the industrial sector. The Laboratory`s technologies can be applied to help companies design products, substitute materials, devise innovative industrial processes, develop advanced quality control systems and instrumentation, and address environmental concerns. The latest techniques and facilities, including those involving modeling, simulation, and high-performance computing, are available to industry and academia. At Argonne, there are opportunities for industry to carry out cooperative research, license inventions, exchange technical personnel, use unique research facilities, and attend conferences and workshops. Technology transfer is one of the Laboratory`s major missions. High priority is given to strengthening U.S. technological competitiveness through research and development partnerships with industry that capitalize on Argonne`s expertise and facilities. The Laboratory is one of three DOE superconductivity technology centers, focusing on manufacturing technology for high-temperature superconducting wires, motors, bearings, and connecting leads. Argonne National Laboratory is operated by the University of Chicago for the U.S. Department of Energy.

  17. Scientific Openness and National Security at the National Laboratories

    NASA Astrophysics Data System (ADS)

    McTague, John

    2000-04-01

    The possible loss to the People's Republic of China of important U.S. nuclear-weapons-related information has aroused concern about interactions of scientists employed by the national laboratories with foreign nationals. As a result, the National Academies assembled a committee to examine the roles of the national laboratories, the contribution of foreign interactions to the fulfillment of those roles, the risks and benefits of scientific openness in this context, and the merits and liabilities of the specific policies being implemented or proposed with respect to contacts with foreign nationals. The committee concluded that there are many aspects of the work at the laboratories that benefit from or even demand the opportunity for foreign interactions. The committee recommended five principles for guiding policy: (1) Maintain balance. Policy governing international dialogue by laboratory staff should seek to encourage international engagement in some areas, while tightly controlling it in others. (2) Educate staff. Security procedures should be clear, easy to follow, and serve an understandable purpose. (3) Streamline procedures. Good science is compatible with good security if there is intelligent line management both at the labs and in Washington, which applies effective tools for security in a sensible fashion. (4) Focus efforts. DOE should focus its efforts governing tightened security for information. The greatest attention should obviously be provided to the protection of classified information by appropriate physical and cybersecurity measures, and by personnel procedures and training. (5) Beware of prejudice against foreigners. Over the past half-century foreign-born individuals have contributed broadly and profoundly to national security through their work at the national laboratories.

  18. Nuclear Science and Physics Data from the Isotopes Project, Lawrence Berkeley National Laboratory (LBNL)

    DOE Data Explorer

    The Isotopes Project pages at Lawrence Berkeley National Laboratory have been a source of nuclear data and reference information since the mid-nineties. Almost all of the data, the results of analyses, the specialized charts and interfaces, and the extensive bibiographic references are fed to the National Nuclear Data Center (NNDC) at Brookhaven National Laboratory and maintained there. The Isotope Project pages at LBNL provide a glimpse of early versions for many of the nuclear data resources.

  19. Saving Water at Los Alamos National Laboratory

    ScienceCinema

    Erickson, Andy

    2016-07-12

    Los Alamos National Laboratory decreased its water usage by 26 percent in 2014, with about one-third of the reduction attributable to using reclaimed water to cool a supercomputing center. The Laboratory's goal during 2014 was to use only re-purposed water to support the mission at the Strategic Computing Complex. Using reclaimed water from the Sanitary Effluent Reclamation Facility, or SERF, substantially decreased water usage and supported the overall mission. SERF collects industrial wastewater and treats it for reuse. The reclamation facility contributed more than 27 million gallons of re-purposed water to the Laboratory's computing center, a secured supercomputing facility that supports the Laboratory’s national security mission and is one of the institution’s larger water users. In addition to the strategic water reuse program at SERF, the Laboratory reduced water use in 2014 by focusing conservation efforts on areas that use the most water, upgrading to water-conserving fixtures, and repairing leaks identified in a biennial survey.

  20. Idaho National Laboratory Cultural Resource Management Plan

    SciTech Connect

    Julie Braun Williams

    2013-02-01

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The purpose of this Cultural Resource Management Plan is to describe how the Department of Energy, Idaho Operations Office will meet these responsibilities at Idaho National Laboratory in southeastern Idaho. The Idaho National Laboratory is home to a wide variety of important cultural resources representing at least 13,500 years of human occupation in the southeastern Idaho area. These resources are nonrenewable, bear valuable physical and intangible legacies, and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these sites with the management and ongoing operation of an active scientific laboratory. The Department of Energy, Idaho Operations Office is committed to a cultural resource management program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative mandates. This document is designed for multiple uses and is intended to be flexible and responsive to future changes in law or mission. Document flexibility and responsiveness will be assured through regular reviews and as-needed updates. Document content includes summaries of Laboratory cultural resource philosophy and overall Department of Energy policy; brief contextual overviews of Laboratory missions, environment, and cultural history; and an overview of cultural resource management practices. A series of appendices

  1. Technology transfer in the national laboratories

    SciTech Connect

    Yonas, G.

    1991-08-01

    The title of this paper might unfairly provoke readers if it conjures up visions of vast stores of high-tech gadgets in several hundred technology warehouses'' (also known as federal laboratories) around the country, open for browsing by those in search of a bargain. That vision, unfortunately, is a mirage. The term technology transfer'' is not really as accurate as is the term technology team-work,'' a process of sharing ideas and knowledge rather than widgets. In addition, instead of discussing the efforts of more than 700 federal labs in the US, I mean to address only those nine government-owned, contractor-operated multiprogram labs run by the Department of Energy. Nevertheless, the topic of technology team-work opportunities with DOE multiprogram national lab is of significance to those concerned with increasing economic competitiveness and finding technological solutions to a host of national problems. A significant fraction of US R D capabilities rests in the nine DOE multiprogram national laboratories -- and these labs have only just begun to join the other federal laboratories in these efforts due to the passage and recent implementation of the National Competitiveness Technology Transfer Act of 1989.

  2. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas.

    PubMed

    Yeh, Kenneth B; Adams, Martin; Stamper, Paul D; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D; Richards, Allen L; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community.

  3. National Laboratory Planning: Developing Sustainable Biocontainment Laboratories in Limited Resource Areas

    PubMed Central

    Adams, Martin; Stamper, Paul D.; Dasgupta, Debanjana; Hewson, Roger; Buck, Charles D.; Richards, Allen L.; Hay, John

    2016-01-01

    Strategic laboratory planning in limited resource areas is essential for addressing global health security issues. Establishing a national reference laboratory, especially one with BSL-3 or -4 biocontainment facilities, requires a heavy investment of resources, a multisectoral approach, and commitments from multiple stakeholders. We make the case for donor organizations and recipient partners to develop a comprehensive laboratory operations roadmap that addresses factors such as mission and roles, engaging national and political support, securing financial support, defining stakeholder involvement, fostering partnerships, and building trust. Successful development occurred with projects in African countries and in Azerbaijan, where strong leadership and a clear management framework have been key to success. A clearly identified and agreed management framework facilitate identifying the responsibility for developing laboratory capabilities and support services, including biosafety and biosecurity, quality assurance, equipment maintenance, supply chain establishment, staff certification and training, retention of human resources, and sustainable operating revenue. These capabilities and support services pose rate-limiting yet necessary challenges. Laboratory capabilities depend on mission and role, as determined by all stakeholders, and demonstrate the need for relevant metrics to monitor the success of the laboratory, including support for internal and external audits. Our analysis concludes that alternative frameworks for success exist for developing and implementing capabilities at regional and national levels in limited resource areas. Thus, achieving a balance for standardizing practices between local procedures and accepted international standards is a prerequisite for integrating new facilities into a country's existing public health infrastructure and into the overall international scientific community. PMID:27559843

  4. Research programs at the Department of Energy National Laboratories. Volume 2: Laboratory matrix

    SciTech Connect

    1994-12-01

    For nearly fifty years, the US national laboratories, under the direction of the Department of Energy, have maintained a tradition of outstanding scientific research and innovative technological development. With the end of the Cold War, their roles have undergone profound changes. Although many of their original priorities remain--stewardship of the nation`s nuclear stockpile, for example--pressing budget constraints and new federal mandates have altered their focus. Promotion of energy efficiency, environmental restoration, human health, and technology partnerships with the goal of enhancing US economic and technological competitiveness are key new priorities. The multiprogram national laboratories offer unparalleled expertise in meeting the challenge of changing priorities. This volume aims to demonstrate each laboratory`s uniqueness in applying this expertise. It describes the laboratories` activities in eleven broad areas of research that most or all share in common. Each section of this volume is devoted to a single laboratory. Those included are: Argonne National Laboratory; Brookhaven National Laboratory; Idaho National Engineering Laboratory; Lawrence Berkeley Laboratory; Lawrence Livermore National Laboratory; Los Alamos National Laboratory; National Renewable Energy Laboratory; Oak Ridge National Laboratory; Pacific Northwest Laboratory; and Sandia National Laboratories. The information in this volume was provided by the multiprogram national laboratories and compiled at Lawrence Berkeley Laboratory.

  5. Supplement analysis for continued operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore. Volume 2: Comment response document

    SciTech Connect

    1999-03-01

    The US Department of Energy (DOE), prepared a draft Supplement Analysis (SA) for Continued Operation of Lawrence Livermore National Laboratory (LLNL) and Sandia National Laboratories, Livermore (SNL-L), in accordance with DOE`s requirements for implementation of the National Environmental Policy Act of 1969 (NEPA) (10 Code of Federal Regulations [CFR] Part 1021.314). It considers whether the Final Environmental Impact Statement and Environmental Impact Report for Continued Operation of Lawrence Livermore National Laboratory and Sandia National Laboratories, Livermore (1992 EIS/EIR) should be supplement3ed, whether a new environmental impact statement (EIS) should be prepared, or no further NEPA documentation is required. The SA examines the current project and program plans and proposals for LLNL and SNL-L, operations to identify new or modified projects or operations or new information for the period from 1998 to 2002 that was not considered in the 1992 EIS/EIR. When such changes, modifications, and information are identified, they are examined to determine whether they could be considered substantial or significant in reference to the 1992 proposed action and the 1993 Record of Decision (ROD). DOE released the draft SA to the public to obtain stakeholder comments and to consider those comments in the preparation of the final SA. DOE distributed copies of the draft SA to those who were known to have an interest in LLNL or SNL-L activities in addition to those who requested a copy. In response to comments received, DOE prepared this Comment Response Document.

  6. Public attitudes toward Lawrence Livermore National Laboratory

    SciTech Connect

    Not Available

    1990-05-01

    Charlton Research Company is pleased to present the following summary of findings report for research conducted under contract with Lawrence Livermore National Laboratory. This section provides a brief introduction to the specifications of the study, and a guide to the organization of this report. Although the most sophisticated procedures have been used to collect and analyze the information presented here, it must be remembered that qualitative and quantitative research are not predictions. They are designed to measure public opinion within identifiable statistical limits or accuracy at specific points in time. This research is in no way a prediction of opinion or action at any future point in time. Among the topics covered in the surveys are: openness; National Laboratory; health hazards; radioactivity; uses of plutonium; hazardous waste; groundwater pollution; nuclear weapons; Ballistic Missile Defense; and earthquakes.

  7. Computer technology forecasting at the National Laboratories

    SciTech Connect

    Peskin, A M

    1980-01-01

    The DOE Office of ADP Management organized a group of scientists and computer professionals, mostly from their own national laboratories, to prepare an annually updated technology forecast to accompany the Department's five-year ADP Plan. The activities of the task force were originally reported in an informal presentation made at the ACM Conference in 1978. This presentation represents an update of that report. It also deals with the process of applying the results obtained at a particular computing center, Brookhaven National Laboratory. Computer technology forecasting is a difficult and hazardous endeavor, but it can reap considerable advantage. The forecast performed on an industry-wide basis can be applied to the particular needs of a given installation, and thus give installation managers considerable guidance in planning. A beneficial side effect of this process is that it forces installation managers, who might otherwise tend to preoccupy themselves with immediate problems, to focus on longer term goals and means to their ends. (RWR)

  8. Idaho National Laboratory Cultural Resource Management Plan

    SciTech Connect

    Lowrey, Diana Lee

    2011-02-01

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The purpose of this Cultural Resource Management Plan is to describe how the Department of Energy, Idaho Operations Office will meet these responsibilities at the Idaho National Laboratory. This Laboratory, which is located in southeastern Idaho, is home to a wide variety of important cultural resources representing at least 13,500 years of human occupation in the southeastern Idaho area. These resources are nonrenewable; bear valuable physical and intangible legacies; and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these sites with the management and ongoing operation of an active scientific laboratory. The Department of Energy, Idaho Operations Office is committed to a cultural resource management program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative mandates. This document is designed for multiple uses and is intended to be flexible and responsive to future changes in law or mission. Document flexibility and responsiveness will be assured through annual reviews and as-needed updates. Document content includes summaries of Laboratory cultural resource philosophy and overall Department of Energy policy; brief contextual overviews of Laboratory missions, environment, and cultural history; and an overview of cultural resource management practices. A series of

  9. Idaho National Laboratory Cultural Resource Management Plan

    SciTech Connect

    Lowrey, Diana Lee

    2009-02-01

    As a federal agency, the U.S. Department of Energy has been directed by Congress, the U.S. president, and the American public to provide leadership in the preservation of prehistoric, historic, and other cultural resources on the lands it administers. This mandate to preserve cultural resources in a spirit of stewardship for the future is outlined in various federal preservation laws, regulations, and guidelines such as the National Historic Preservation Act, the Archaeological Resources Protection Act, and the National Environmental Policy Act. The purpose of this Cultural Resource Management Plan is to describe how the Department of Energy, Idaho Operations Office will meet these responsibilities at the Idaho National Laboratory. This Laboratory, which is located in southeastern Idaho, is home to a wide variety of important cultural resources representing at least 13,500 years of human occupation in the southeastern Idaho area. These resources are nonrenewable; bear valuable physical and intangible legacies; and yield important information about the past, present, and perhaps the future. There are special challenges associated with balancing the preservation of these sites with the management and ongoing operation of an active scientific laboratory. The Department of Energy, Idaho Operations Office is committed to a cultural resource management program that accepts these challenges in a manner reflecting both the spirit and intent of the legislative mandates. This document is designed for multiple uses and is intended to be flexible and responsive to future changes in law or mission. Document flexibility and responsiveness will be assured through annual reviews and as-needed updates. Document content includes summaries of Laboratory cultural resource philosophy and overall Department of Energy policy; brief contextual overviews of Laboratory missions, environment, and cultural history; and an overview of cultural resource management practices. A series of

  10. Evaluation of Radiometers Deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory

    SciTech Connect

    Habte, Aron; Wilcox, Stephen; Stoffel, Thomas

    2015-12-23

    This study analyzes the performance of various commercially available radiometers used for measuring global horizontal irradiances and direct normal irradiances. These include pyranometers, pyrheliometers, rotating shadowband radiometers, and a pyranometer with fixed internal shading and are all deployed at the National Renewable Energy Laboratory's Solar Radiation Research Laboratory. Data from 32 global horizontal irradiance and 19 direct normal irradiance radiometers are presented. The radiometers in this study were deployed for one year (from April 1, 2011, through March 31, 2012) and compared to measurements from radiometers with the lowest values of estimated measurement uncertainties for producing reference global horizontal irradiances and direct normal irradiances.

  11. Geothermal programs at Lawrence Livermore National Laboratory

    SciTech Connect

    Kasameyer, P.W.; Younker, L.W.

    1987-07-10

    Lawrence Livermore National Laboratory has a number of geothermal programs supported through two offices in the Department of Energy: the Office of Renewable Technologies, Geothermal Technologies Division, and the Office of Basic Energy Sciences, Division of Engineering, Mathematics and Geosciences. Within these programs, we are carrying out research in injection monitoring, optical instrumentation for geothermal wells, seismic imaging methods, geophysical and drilling investigations of young volcanic systems in California, and fundamental studies of the rock and mineral properties.

  12. Leadership Computing at Oak Ridge National Laboratory

    SciTech Connect

    Kuehn, Jeffery A; Studham, Scott; White III, James B; Fahey, Mark R; Carter, Steven M; Nichols, Jeffrey A

    2005-05-01

    Oak Ridge National Laboratory is running the world's largest Cray X1, the world's largest unclassified Cray XT3, and a Cray XD1. In this report we provide an overview of the applications requiring leadership computing and the performance characteristics of the various platforms at ORNL. We then discuss ways in which we are working with Cray to establish a roadmap that will provide 100's of teraflops of sustained performance while integrating a balance of vector and scalar processors.

  13. Frederick National Laboratory Celebrates 40 Years | Poster

    Cancer.gov

    By Ashley DeVine, Staff Writer Forty years ago, what we now call the Frederick National Laboratory for Cancer Research was born. Here are some highlights in the facility’s history. October 19, 1971 – President Richard Nixon announced that Fort Detrick would be converted from a biological warfare facility to a cancer research center (Covert, Norman M., Cutting Edge: A History of Fort Detrick, Maryland, 1943–1993, pp. 85–87).

  14. Frederick National Laboratory Celebrates 40 Years | Poster

    Cancer.gov

    By Ashley DeVine, Staff Writer Forty years ago, what we now call the Frederick National Laboratory for Cancer Research was born. Here are some highlights in the facility’s history. October 19, 1971 – President Richard Nixon announced that Fort Detrick would be converted from a biological warfare facility to a cancer research center (Covert, Norman M., Cutting Edge: A History of Fort Detrick, Maryland, 1943–1993, pp. 85–87).

  15. The Dalian National Laboratory for Clean Energy.

    PubMed

    Zhang, Tao; Li, Can; Bao, Xinhe

    2012-05-01

    The Dalian Institute of Chemical Physics (DICP), Chinese Academy of Sciences conducts fundamental and applied research towards chemistry and chemical engineering, with strong competence in the development of new technologies. The research in this special issue, containing 19 papers, features some of the DICP's best work on sustainable energy, use of environmental resources, and advanced materials within the framework of the Dalian National Laboratory for Clean Energy (DNL). Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Internship at Los Alamos National Laboratory

    SciTech Connect

    Dunham, Ryan Q.

    2012-07-11

    Los Alamos National Laboratory (LANL) is located in Los Alamos, New Mexico. It provides support for our country's nuclear weapon stockpile as well as many other scientific research projects. I am an Undergraduate Student Intern in the Systems Design and Analysis group within the Nuclear Nonproliferation division of the Global Security directorate at LANL. I have been tasked with data analysis and modeling of particles in a fluidized bed system for the capture of carbon dioxide from power plant flue gas.

  17. Oak Ridge National Laboratory Waste Management Plan

    SciTech Connect

    Not Available

    1992-12-01

    The objective of the Oak Ridge National Laboratory Waste Management Plan is to compile and to consolidate information annually on how the ORNL Waste Management Program is conducted, which waste management facilities are being used to manage wastes, what forces are acting to change current waste management systems, what activities are planned for the forthcoming fiscal year (FY), and how all of the activities are documented.

  18. Radiographic testing at Lawrence Livermore National Laboratory

    SciTech Connect

    Bossi, R.H.

    1982-04-21

    Radiographic testing is a nondestructive inspection technique which uses penetrating radiation. The Nondestructive Evaluation (NDE) Section at Lawrence Livermore National Laboratory has a broad spectrum of equipment and techniques for radiographic testing. These resources include low-energy vacuum systems, low- and mid-energy cabinet and cell radiographic systems, high-energy linear accelerators, portable x-ray machines and radioisotopes for radiographic inspections. For diagnostic testing the NDE Section also has real-time and flash radiographic equipment.

  19. National Water Quality Laboratory, 1995 services catalog

    USGS Publications Warehouse

    Timme, P.J.

    1995-01-01

    This Services Catalog contains information about field supplies and analytical services available from the National Water Quality Laboratory in Denver, Colo., and field supplies available from the Quality Water Service Unit in Ocala, Fla., to members of the U.S. Geological Survey. To assist personnel in the selection of analytical services, this catalog lists sample volume, required containers, applicable concentration range, detection level, precision of analysis, and preservation requirements for samples.

  20. National Renewable Energy Laboratory 2005 Research Review

    SciTech Connect

    Brown, H.; Gwinner, D.; Miller, M.; Pitchford, P.

    2006-06-01

    Science and technology are at the heart of everything we do at the National Renewable Energy Laboratory, as we pursue innovative, robust, and sustainable ways to produce energy--and as we seek to understand and illuminate the physics, chemistry, biology, and engineering behind alternative energy technologies. This year's Research Review highlights the Lab's work in the areas of alternatives fuels and vehicles, high-performing commercial buildings, and high-efficiency inverted, semi-mismatched solar cells.

  1. The Brookhaven National Laboratory Accelerator Test Facility

    SciTech Connect

    Batchelor, K.

    1992-01-01

    The Brookhaven National Laboratory Accelerator Test Facility comprises a 50 MeV traveling wave electron linear accelerator utilizing a high gradient, photo-excited, raidofrequency electron gun as an injector and an experimental area for study of new acceleration methods or advanced radiation sources using free electron lasers. Early operation of the linear accelerator system including calculated and measured beam parameters are presented together with the experimental program for accelerator physics and free electron laser studies.

  2. The Brookhaven National Laboratory Accelerator Test Facility

    SciTech Connect

    Batchelor, K.

    1992-09-01

    The Brookhaven National Laboratory Accelerator Test Facility comprises a 50 MeV traveling wave electron linear accelerator utilizing a high gradient, photo-excited, raidofrequency electron gun as an injector and an experimental area for study of new acceleration methods or advanced radiation sources using free electron lasers. Early operation of the linear accelerator system including calculated and measured beam parameters are presented together with the experimental program for accelerator physics and free electron laser studies.

  3. Saving Water at Los Alamos National Laboratory

    SciTech Connect

    Erickson, Andy

    2015-03-16

    Los Alamos National Laboratory decreased its water usage by 26 percent in 2014, with about one-third of the reduction attributable to using reclaimed water to cool a supercomputing center. The Laboratory's goal during 2014 was to use only re-purposed water to support the mission at the Strategic Computing Complex. Using reclaimed water from the Sanitary Effluent Reclamation Facility, or SERF, substantially decreased water usage and supported the overall mission. SERF collects industrial wastewater and treats it for reuse. The reclamation facility contributed more than 27 million gallons of re-purposed water to the Laboratory's computing center, a secured supercomputing facility that supports the Laboratory’s national security mission and is one of the institution’s larger water users. In addition to the strategic water reuse program at SERF, the Laboratory reduced water use in 2014 by focusing conservation efforts on areas that use the most water, upgrading to water-conserving fixtures, and repairing leaks identified in a biennial survey.

  4. Lawrence Livermore National Laboratory 2007 Annual Report

    SciTech Connect

    Chrzanowski, P; Walter, K

    2008-04-25

    Lawrence Livermore National Laboratory's many outstanding accomplishments in 2007 are a tribute to a dedicated staff, which is shaping the Laboratory's future as we go through a period of transition and transformation. The achievements highlighted in this annual report illustrate our focus on the important problems that affect our nation's security and global stability, our application of breakthrough science and technology to tackle those problems, and our commitment to safe, secure, and efficient operations. In May 2007, the Department of Energy (DOE) awarded Lawrence Livermore National Security, LLC (LLNS), a new public-private partnership, the contract to manage and operate the Laboratory starting in October. Since its inception in 1952, the Laboratory had been managed by the University of California (UC) for the DOE's National Nuclear Security Administration (NNSA) and predecessor organizations. UC is one of the parent organizations that make up LLNS, and UC's presence in the new management entity will help us carry forward our strong tradition of multidisciplinary science and technology. 'Team science' applied to big problems was pioneered by the Laboratory's co-founder and namesake, Ernest O. Lawrence, and has been our hallmark ever since. Transition began fully a year before DOE's announcement. More than 1,600 activities had to be carried out to transition the Laboratory from management by a not-for-profit to a private entity. People, property, and procedures as well as contracts, formal agreements, and liabilities had to be transferred to LLNS. The pre-transition and transition teams did a superb job, and I thank them for their hard work. Transformation is an ongoing process at Livermore. We continually reinvent ourselves as we seek breakthroughs that impact emerging national needs. An example is our development in the late 1990s of a portable instrument that could rapidly detect DNA signatures, research that started with a view toward the potential threat

  5. Lawrence Livermore National Laboratory Annual Report 2006

    SciTech Connect

    Chrzanowski, P; Walter, K

    2007-05-24

    For the Laboratory and staff, 2006 was a year of outstanding achievements. As our many accomplishments in this annual report illustrate, the Laboratory's focus on important problems that affect our nation's security and our researchers breakthroughs in science and technology have led to major successes. As a national laboratory that is part of the Department of Energy's National Nuclear Security Administration (DOE/NNSA), Livermore is a key contributor to the Stockpile Stewardship Program for maintaining the safety, security, and reliability of the nation's nuclear weapons stockpile. The program has been highly successful, and our annual report features some of the Laboratory's significant stockpile stewardship accomplishments in 2006. A notable example is a long-term study with Los Alamos National Laboratory, which found that weapon pit performance will not sharply degrade from the aging effects on plutonium. The conclusion was based on a wide range of nonnuclear experiments, detailed simulations, theoretical advances, and thorough analyses of the results of past nuclear tests. The study was a superb scientific effort. The continuing success of stockpile stewardship enabled NNSA in 2006 to lay out Complex 2030, a vision for a transformed nuclear weapons complex that is more responsive, cost efficient, and highly secure. One of the ways our Laboratory will help lead this transformation is through the design and development of reliable replacement warheads (RRWs). Compared to current designs, these warheads would have enhanced performance margins and security features and would be less costly to manufacture and maintain in a smaller, modernized production complex. In early 2007, NNSA selected Lawrence Livermore and Sandia National Laboratories-California to develop ''RRW-1'' for the U.S. Navy. Design efforts for the RRW, the plutonium aging work, and many other stockpile stewardship accomplishments rely on computer simulations performed on NNSA's Advanced Simulation

  6. Oak Ridge National Laboratory Core Competencies

    SciTech Connect

    Roberto, J.B.; Anderson, T.D.; Berven, B.A.; Hildebrand, S.G.; Hartman, F.C.; Honea, R.B.; Jones, J.E. Jr.; Moon, R.M. Jr.; Saltmarsh, M.J.; Shelton, R.B.

    1994-12-01

    A core competency is a distinguishing integration of capabilities which enables an organization to deliver mission results. Core competencies represent the collective learning of an organization and provide the capacity to perform present and future missions. Core competencies are distinguishing characteristics which offer comparative advantage and are difficult to reproduce. They exhibit customer focus, mission relevance, and vertical integration from research through applications. They are demonstrable by metrics such as level of investment, uniqueness of facilities and expertise, and national impact. The Oak Ridge National Laboratory (ORNL) has identified four core competencies which satisfy the above criteria. Each core competency represents an annual investment of at least $100M and is characterized by an integration of Laboratory technical foundations in physical, chemical, and materials sciences; biological, environmental, and social sciences; engineering sciences; and computational sciences and informatics. The ability to integrate broad technical foundations to develop and sustain core competencies in support of national R&D goals is a distinguishing strength of the national laboratories. The ORNL core competencies are: 9 Energy Production and End-Use Technologies o Biological and Environmental Sciences and Technology o Advanced Materials Synthesis, Processing, and Characterization & Neutron-Based Science and Technology. The distinguishing characteristics of each ORNL core competency are described. In addition, written material is provided for two emerging competencies: Manufacturing Technologies and Computational Science and Advanced Computing. Distinguishing institutional competencies in the Development and Operation of National Research Facilities, R&D Integration and Partnerships, Technology Transfer, and Science Education are also described. Finally, financial data for the ORNL core competencies are summarized in the appendices.

  7. Computational geomechanics & applications at Sandia National Laboratories.

    SciTech Connect

    Arguello, Jose Guadalupe, Jr.

    2010-04-01

    Sandia National Laboratories (SNL) is a multi-program national laboratory in the business of national security, whose primary mission is nuclear weapons (NW). It is a prime contractor to the USDOE, operating under the NNSA and is one of the three NW national laboratories. It has a long history of involvement in the area of geomechanics, starting with the some of the earliest weapons tests at Nevada. Projects in which geomechanics support (in general) and computational geomechanics support (in particular) are at the forefront at Sandia, range from those associated with civilian programs to those in the defense programs. SNL has had significant involvement and participation in the Waste Isolation Pilot Plant (low-level defense nuclear waste), the Yucca Mountain Project (formerly proposed for commercial spent fuel and high-level nuclear waste), and the Strategic Petroleum Reserve (the nation's emergency petroleum store). In addition, numerous industrial partners seek-out our computational/geomechanics expertise, and there are efforts in compressed air and natural gas storage, as well as in CO{sub 2} Sequestration. Likewise, there have also been collaborative past efforts in the areas of compactable reservoir response, the response of salt structures associated with reservoirs, and basin modeling for the Oil & Gas industry. There are also efforts on the defense front, ranging from assessment of vulnerability of infrastructure to defeat of hardened targets, which require an understanding and application of computational geomechanics. Several examples from some of these areas will be described and discussed to give the audience a flavor of the type of work currently being performed at Sandia in the general area of geomechanics.

  8. Produce and fish sampling program of Los Alamos National Laboratory's Environmental Surveillance Group

    SciTech Connect

    Salazar, J.G.

    1984-09-01

    This report describes produce and fish sampling procedures of the Environmental Surveillance Group at the Los Alamos National Laboratory. The program monitors foodstuffs and fish for possible radioactive contamination from Laboratory operations. Data gathered in this program on radionuclide concentrations help to estimate radiation doses to Laboratory personnel and the public. 3 references, 7 figures, 2 tables.

  9. Space robotics programs at Sandia National Laboratories

    SciTech Connect

    Klarer, P.

    1993-01-01

    Existing robotic rover and space satellite technologies at Sandia National Laboratories (SNL), coupled with existing launch vehicles and converted military Multiple Independent Reentry Vehicle (MIRV) technologies, can be applied towards the realization of a robotic lunar rover mission in the near term. SNL`s Advanced Vehicle Development Department has been designing, producing, and operating prototype rover systems at the Robotic Vehicle Range facility since 1984, and has extensive experience with teleoperated and semiautonomous mobile robotic systems. SNL`s Space Systems Directorate has been designing, producing, and operating satellite systems and subsystems in earth orbit for national security missions since the early 1960`s. The facilities and robotic vehicle fleet at SNL`s Robotic Vehicle Range (SNL-RVR) have been used to support technology base development in applications ranging from DoD battlefield and security missions, to multi-agency nuclear emergency response team exercises and the development of a prototype robotic rover for planetary exploration. Recent activities at the SNL-RVR include the Robotic All Terrain Lunar Exploration Rover (RATLER) prototype development program, exploratory studies on a Near Term Lunar Return Mission scenario for small robotic rovers based on existing space hardware technology, and demonstrations of the utility of existing rover technologies for performing remote field geology tasks similar to those envisioned on a robotic lunar rover mission. Specific technologies demonstrated include low data rate teleoperation, multi-vehicle control, remote site and sample inspection, and standard bandwidth stereo vision. The paper describes Sandia National Laboratories` activities in the Space Robotics area, and highlights the laboratory`s supporting technical capabilities.

  10. Diagnosing Malaria Cases Referred to the Malaria Reference Laboratory in Tehran University of Medical Science, Iran

    PubMed Central

    NATEGHPOUR, Mehdi; EDRISSIAN, Gholamhossein; MOTEVALLI HAGHI, Afsaneh; FARIVAR, Leila; KAZEMI-RAD, Elham

    2015-01-01

    Background: The number of malaria cases is declining worldwide; however, it remains as a serious health problem. Diagnosing unusual cases is the most important issue to manage the problem. This study designed to describe the number of falciparum and vivax malaria infected patients referred to Malaria Reference Laboratory in Tehran University of Medical Science from 2000 to 2012. Methods: A retrospective study was conducted based on the collected questionnaires from each patient referred to the laboratory. Diagnosing results and demographic information for positive cases were analyzed using SPSS software. Problematic cases were evaluated for any difficulties in diagnosis or in clinical signs. Scanning and molecular methods were performed whenever there was an atypical case referred to the laboratory. Some of the samples had various difficulties for diagnosing such as presence of fussed gametocytes and schizonts of Plasmodium falciparum in peripheral blood and CCHF like hemoragic disorders. Results: Plasmodium vivax caused a large proportion of the cases (76.1%) in contrast with P. falciparum that included smaller proportion (22.8%) and the rest (1.1) belonged to mixed infection. Most of the positive cases (69.6%) were belonged to Afghani people. Men (94.6%) showed more infection than women (5.4%), moreover the most infection (44.5%) was seen at a range of 21–30 yr. Conclusion: In the case of existing atypical issues to diagnose, it is needed to perform more precise microscopical examination beyond the current standard conditions. Sometimes molecular method is required to verify the exact agent of the disease. PMID:26811720

  11. Secondary calibration laboratory for ionizing radiation laboratory accreitation program National Institute of Standards and Technology National Voluntary Laboratory Accreditation Program

    SciTech Connect

    Martin, P.R.

    1993-12-31

    This paper presents an overview of the procedures and requirements for accreditation under the Secondary Calibration Laboratory for Ionizing Radiation Program (SCLIR LAP). The requirements for a quality system, proficiency testing and the onsite assessment are discussed. The purpose of the accreditation program is to establish a network of secondary calibration laboratories that can provide calibrations traceable to the primary national standards.

  12. The National Laboratory Gene Library Project

    SciTech Connect

    Deaven, L.L.; Van Dilla, M.A.

    1988-01-01

    The two National Laboratories at Livermore and Los Alamos have played a prominent role in the development and application of flow cytometry and sorting to chromosome classification and purification. Both laboratories began to receive numerous requests for specific human chromosomal types purified by flow sorting for gene library construction, but these requests were difficult to satisfy due to time and personnel constraints. The Department of Energy, through its Office of Health and Environmental Research, has a long-standing interest in the human genome in general and in the mutagenic and carcinogenic effects of energy-related environmental pollutants in particular. Hence, it was decided in 1983 to use the flow construct chromosome-specific gene libraries to be made available to the genetic research community. The National Laboratory Gene Library Project was envisioned as a practical way to deal with requests for sorted chromosomes, and also as a way to promote increased understanding of the human genome and the effects of mutagens and carcinogens on it. The strategy for the project was developed with the help of an advisory committee as well as suggestions and advice from many other geneticists. 4 refs., 2 tabs.

  13. Los Alamos National Laboratory building cost index

    SciTech Connect

    Orr, H.D.; Lemon, G.D.

    1982-10-01

    The Los Alamos National Laboratory Building Cost Index indicates that actual escalation since 1970 is near 10% per year. Therefore, the Laboratory will continue using a 10% per year escalation rate for construction estimates through 1985 and a slightly lower rate of 8% per year from 1986 through 1990. The computerized program compares the different elements involved in the cost of a typical construction project, which for our purposes, is a complex of office buildings and experimental laboratories. The input data used in the program consist primarily of labor costs and material and equipment costs. The labor costs are the contractual rates of the crafts workers in the Los Alamos area. For the analysis, 12 field-labor craft categories are used; each is weighted corresponding to the labor craft distribution associated with the typical construction project. The materials costs are current Los Alamos prices. Additional information sources include material and equipment quotes obtained through conversations with vendors and from trade publications. The material and equipment items separate into 17 categories for the analysis and are weighted corresponding to the material and equipment distribution associated with the typical construction project. The building cost index is compared to other national building cost indexes.

  14. Oak Ridge National Laboratory`s isotope enrichment program

    SciTech Connect

    Tracy, J.G.; Aaron, W.C.

    1997-12-01

    The Isotope Enrichment Program (IEP) at Oak Ridge National Laboratory (ORNL) is responsible for the production and distribution of {approximately}225 enriched stable isotopes from 50 multi-isotopic elements. In addition, ORNL distributes enriched actinide isotopes and provides extensive physical- and chemical-form processing of enriched isotopes to meet customer requirements. For more than 50 yr, ORNL has been a major provider of enriched isotopes and isotope-related services to research, medical, and industrial institutions throughout the world. Consolidation of the Isotope Distribution Office (IDO), the Isotope Research Materials Laboratory (IRML), and the stable isotope inventories in the Isotope Enrichment Facility (IEF) have improved operational efficiencies and customer services. Recent changes in the IEP have included adopting policies for long-term contracts, which offer program stability and pricing advantages for the customer, and prorated service charges, which greatly improve pricing to the small research users. The former U.S. Department of Energy (DOE) Loan Program has been converted to a lease program, which makes large-quantity or very expensive isotopes available for nondestructive research at a nominal cost. Current efforts are being pursued to improve and expand the isotope separation capabilities as well as the extensive chemical- and physical-form processing that now exists. The IEF`s quality management system is ISO 9002 registered and accredited in the United States, Canada, and Europe.

  15. Battery testing at Argonne National Laboratory

    NASA Astrophysics Data System (ADS)

    Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

    Advanced battery technology evaluations are performed under simulated electric-vehicle operating conditions at the Analysis & Diagnostic Laboratory (ADL) of Argonne National Laboratory. The ADL results provide insight into those factors that limit battery performance and life. The ADL facilities include a test laboratory to conduct battery experimental evaluations under simulated application conditions and a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. This paper summarizes the performance characterizations and life evaluations conducted during FY-92 on both single cells and multi-cell modules that encompass six battery technologies (Na/S, Li/FeS, Ni/Metal-Hydride, Ni/Zn, Ni/Cd, Ni/Fe). These evaluations were performed for the Department of Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division, and the Electric Power Research Institute. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The results help identify the most promising R&D approaches for overcoming battery limitations, and provide battery users, developers, and program managers with a measure of the progress being made in battery R&D programs, a comparison of battery technologies, and basic data for modeling.

  16. Battery testing at Argonne National Laboratory

    SciTech Connect

    DeLuca, W.H.; Gillie, K.R.; Kulaga, J.E.; Smaga, J.A.; Tummillo, A.F.; Webster, C.E.

    1992-01-01

    Advanced battery technology evaluations are performed under simulated electric-vehicle operating conditions at the Analysis Diagnostic Laboratory (ADL) of Argonne National Laboratory. The ADL results provide insight into those factors that limit battery performance and life. The ADL facilities include a test laboratory to conduct battery experimental evaluations under simulated application conditions and a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. This paper summarizes the performance characterizations and life evaluations conducted during FY 1992 on both single cells and multi-cell modules that encompass six battery technologies [Na/S, Li/FeS, Ni/Metal-Hydride, Ni/Zn, Ni/Cd, Ni/Fe]. These evaluations were performed for the Department of Energy, Office of Transportation Technologies, Electric and Hybrid Propulsion Division, and the Electric Power Research Institute. The ADL provides a common basis for battery performance characterization and lie evaluations with unbiased application of tests and analyses. The results help identify the most promising R D approaches for overcoming battery limitations, and provide battery users, developers, and program managers with a measure of the progress being made in battery R D programs, a comparison of battery technologies, and basic data for modeling.

  17. Battery testing at Argonne National Laboratory

    SciTech Connect

    DeLuca, W.H.; Gillie, K.R.; Kulaga, J.E.; Smaga, J.A.; Tummillo, A.F.; Webster, C.E.

    1993-03-25

    Argonne National Laboratory`s Analysis & Diagnostic Laboratory (ADL) tests advanced batteries under simulated electric and hybrid vehicle operating conditions. The ADL facilities also include a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The battery evaluations and post-test examinations help identify factors that limit system performance and life, and the most-promising R&D approaches for overcoming these limitations. Since 1991, performance characterizations and/or life evaluations have been conducted on eight battery technologies (Na/S, Li/S, Zn/Br, Ni/MH, Ni/Zn, Ni/Cd, Ni/Fe, and lead-acid). These evaluations were performed for the Department of Energy`s. Office of Transportation Technologies, Electric and Hybrid Propulsion Division (DOE/OTT/EHP), and Electric Power Research Institute (EPRI) Transportation Program. The results obtained are discussed.

  18. Reference ranges for the clinical laboratory derived from a rural population in Kericho, Kenya.

    PubMed

    Kibaya, Rukia S; Bautista, Christian T; Sawe, Frederick K; Shaffer, Douglas N; Sateren, Warren B; Scott, Paul T; Michael, Nelson L; Robb, Merlin L; Birx, Deborah L; de Souza, Mark S

    2008-10-03

    The conduct of Phase I/II HIV vaccine trials internationally necessitates the development of region-specific clinical reference ranges for trial enrollment and participant monitoring. A population based cohort of adults in Kericho, Kenya, a potential vaccine trial site, allowed development of clinical laboratory reference ranges. Lymphocyte immunophenotyping was performed on 1293 HIV seronegative study participants. Hematology and clinical chemistry were performed on up to 1541 cohort enrollees. The ratio of males to females was 1.9:1. Means, medians and 95% reference ranges were calculated and compared with those from other nations. The median CD4+ T cell count for the group was 810 cells/microl. There were significant gender differences for both red and white blood cell parameters. Kenyan subjects had lower median hemoglobin concentrations (9.5 g/dL; range 6.7-11.1) and neutrophil counts (1850 cells/microl; range 914-4715) compared to North Americans. Kenyan clinical chemistry reference ranges were comparable to those from the USA, with the exception of the upper limits for bilirubin and blood urea nitrogen, which were 2.3-fold higher and 1.5-fold lower, respectively. This study is the first to assess clinical reference ranges for a highland community in Kenya and highlights the need to define clinical laboratory ranges from the national community not only for clinical research but also care and treatment.

  19. Reference Ranges for the Clinical Laboratory Derived from a Rural Population in Kericho, Kenya

    PubMed Central

    Kibaya, Rukia S.; Bautista, Christian T.; Sawe, Frederick K.; Shaffer, Douglas N.; Sateren, Warren B.; Scott, Paul T.; Michael, Nelson L.; Robb, Merlin L.; Birx, Deborah L.; de Souza, Mark S.

    2008-01-01

    The conduct of Phase I/II HIV vaccine trials internationally necessitates the development of region-specific clinical reference ranges for trial enrolment and participant monitoring. A population based cohort of adults in Kericho, Kenya, a potential vaccine trial site, allowed development of clinical laboratory reference ranges. Lymphocyte immunophenotyping was performed on 1293 HIV seronegative study participants. Hematology and clinical chemistry were performed on up to 1541 cohort enrollees. The ratio of males to females was 1.9∶1. Means, medians and 95% reference ranges were calculated and compared with those from other nations. The median CD4+ T cell count for the group was 810 cells/µl. There were significant gender differences for both red and white blood cell parameters. Kenyan subjects had lower median hemoglobin concentrations (9.5 g/dL; range 6.7–11.1) and neutrophil counts (1850 cells/µl; range 914–4715) compared to North Americans. Kenyan clinical chemistry reference ranges were comparable to those from the USA, with the exception of the upper limits for bilirubin and blood urea nitrogen, which were 2.3-fold higher and 1.5-fold lower, respectively. This study is the first to assess clinical reference ranges for a highland community in Kenya and highlights the need to define clinical laboratory ranges from the national community not only for clinical research but also care and treatment. PMID:18833329

  20. Stirling engine research at Argonne National Laboratory

    SciTech Connect

    Holtz, R.E.; Daley, J.G.; Roach, P.D.

    1986-06-01

    Stirling engine research at Argonne National Laboratory has been focused at (1) development of mathematical models and analytical tools for predicting component and engine performance, and (2) experimental research into fundamental heat transfer and fluid flow phenomena occurring in Stirling cycle devices. A result of the analytical effort has been the formation of a computer library specifically for Stirling engine researchers and developers. The library contains properties of structural materials commonly used, thermophysical properties of several working fluids, correlations for heat transfer calculations and general specifications of mechanical arrangements (including various drive mechanisms) that can be utilized to model a particular engine. The library also contains alternative modules to perform analysis at different levels of sophistication, including design optimization. A reversing flow heat transfer facility is operating at Argonne to provide data at prototypic Stirling engine operating conditions under controlled laboratory conditions. This information is needed to validate analytical models.

  1. Reference Intervals, Intraindividual and Interindividual Variability, and Reference Change Values for Hematologic Variables in Laboratory Beagles

    PubMed Central

    Bourgès-Abella, Nathalie H; Gury, Thierry D; Geffré, Anne; Concordet, Didier; Thibault-Duprey, Kevin C; Dauchy, Arnaud; Trumel, Catherine

    2015-01-01

    In research and development studies for human and veterinary medicine, relevant comparators for interpreting clinical pathology results are matched with concurrent control animals. However, reference intervals (RI) provide a comparator database and important aids for interpreting clinical pathology data, especially in laboratory beagle dogs. Furthermore, RI incorporate biologic variation, which includes analytical, intraindividual, and interindividual variation. No studies to date have established RI and studied the effect of biologic variation on hematologic variables in a large group of laboratory dogs. The purpose of this retrospective study was to establish hematologic RI for laboratory beagles according to international recommendations and estimate the effect of biologic variation in routinely measured hematologic analytes by using the databank at a pharmaceutical center. Blood specimens from 340 healthy beagles (age, 9 to 36 mo) were evaluated by using a flow-cytometry-based hematology analyzer. RI and their 90% confidence intervals were established by using a nonparametric method. Effects of sex, age, and weight were investigated. Weight had no effect on any analyte. RBC, Hgb, Hct, MCV, MCH, RBC distribution width, and platelet count increased with age, whereas WBC count decreased. The only clinically relevant effect of sex was observed for platelets, which were lower in male beagles than in female and warranted 2 different RI. The calculated index of individuality showed that population-based RI were appropriate for almost all hematologic analytes, as might be expected for a homogeneous group of laboratory beagles. PMID:25651086

  2. Laboratory testing of West Valley reference 6 glass

    SciTech Connect

    Ebert, W.L.

    1995-07-01

    A series of laboratory tests is being conducted to characterize the corrosion of West Valley reference 6 glass (WV6) and to provide parametric values for modeling its long-term durability. Models require measurement of the corrosion rate in the absence of corrosion products and in fluids that are {open_quotes}saturated{close_quotes} with corrosion products, and the identification of alteration phases. Corrosion rates in dilute and saturated conditions were measured using MCC-1 and PCT tests, respectively. Vapor hydration tests were performed to generate secondary phases. The PCT tests show the WV6 glass to be more durable than SRL EA, SRL 202, and HW-39-1 glasses. Vapor hydration tests show weeksite (a uranyl silicate), a potassium-bearing zeolite, analcime, potassium feldspar, a calcium silicate phase, and lithium phosphate to form as WV6 glass corrodes. Test results are presented and their relevance to long-term performance discussed.

  3. 1990 National Water Quality Laboratory Services Catalog

    USGS Publications Warehouse

    Pritt, Jeffrey; Jones, Berwyn E.

    1989-01-01

    PREFACE This catalog provides information about analytical services available from the National Water Quality Laboratory (NWQL) to support programs of the Water Resources Division of the U.S. Geological Survey. To assist personnel in the selection of analytical services, the catalog lists cost, sample volume, applicable concentration range, detection level, precision of analysis, and preservation techniques for samples to be submitted for analysis. Prices for services reflect operationa1 costs, the complexity of each analytical procedure, and the costs to ensure analytical quality control. The catalog consists of five parts. Part 1 is a glossary of terminology; Part 2 lists the bottles, containers, solutions, and other materials that are available through the NWQL; Part 3 describes the field processing of samples to be submitted for analysis; Part 4 describes analytical services that are available; and Part 5 contains indices of analytical methodology and Chemical Abstract Services (CAS) numbers. Nomenclature used in the catalog is consistent with WATSTORE and STORET. The user is provided with laboratory codes and schedules that consist of groupings of parameters which are measured together in the NWQL. In cases where more than one analytical range is offered for a single element or compound, different laboratory codes are given. Book 5 of the series 'Techniques of Water Resources Investigations of the U.S. Geological Survey' should be consulted for more information about the analytical procedures included in the tabulations. This catalog supersedes U.S. Geological Survey Open-File Report 86-232 '1986-87-88 National Water Quality Laboratory Services Catalog', October 1985.

  4. Space robotics programs at Sandia National Laboratories

    SciTech Connect

    Klarer, P.

    1993-01-01

    Existing robotic rover and space satellite technologies at Sandia National Laboratories (SNL), coupled with existing launch vehicles and converted military Multiple Independent Reentry Vehicle (MIRV) technologies, can be applied towards the realization of a robotic lunar rover mission in the near term. SNL's Advanced Vehicle Development Department has been designing, producing, and operating prototype rover systems at the Robotic Vehicle Range facility since 1984, and has extensive experience with teleoperated and semiautonomous mobile robotic systems. SNL's Space Systems Directorate has been designing, producing, and operating satellite systems and subsystems in earth orbit for national security missions since the early 1960's. The facilities and robotic vehicle fleet at SNL's Robotic Vehicle Range (SNL-RVR) have been used to support technology base development in applications ranging from DoD battlefield and security missions, to multi-agency nuclear emergency response team exercises and the development of a prototype robotic rover for planetary exploration. Recent activities at the SNL-RVR include the Robotic All Terrain Lunar Exploration Rover (RATLER) prototype development program, exploratory studies on a Near Term Lunar Return Mission scenario for small robotic rovers based on existing space hardware technology, and demonstrations of the utility of existing rover technologies for performing remote field geology tasks similar to those envisioned on a robotic lunar rover mission. Specific technologies demonstrated include low data rate teleoperation, multi-vehicle control, remote site and sample inspection, and standard bandwidth stereo vision. The paper describes Sandia National Laboratories' activities in the Space Robotics area, and highlights the laboratory's supporting technical capabilities.

  5. The National High Magnetic Field Laboratory

    NASA Astrophysics Data System (ADS)

    Schneider-Muntau, H. J.; Brandt, B. L.; Brunel, L. C.; Cross, T. A.; Edison, A. S.; Marshall, A. G.; Reyes, A. P.

    2004-04-01

    We describe two of the main user facilities of the National High Magnetic Field Laboratory (NHMFL): (a) the General Purpose DC Field Facility with nine resistive and hybrid magnet stations with continuous fields between 20 and 45 T, and (b) the CIMAR Facilities with 17 spectrometers for the NMR Spectroscopy and Imaging Program, the Fourier Transform ICR Mass Spectrometry Program and the Electron Magnetic Resonance Spectroscopy Program. The facilities are located in Tallahassee, and Gainesville, FL. Members of the worldwide science and engineering communities can access NHMFL facilities, generally without cost, through a peer-reviewed proposal process.

  6. MEMS packaging efforts at Sandia National Laboratories.

    SciTech Connect

    Custer, Jonathan Sloane

    2003-02-01

    Sandia National Laboratories has programs covering a broad range of MEMS technologies from LIGA to bulk to surface micromachining. These MEMS technologies are being considered for an equally broad range of applications, including sensors, actuators, optics, and microfluidics. As these technologies have moved from the research to the prototype product stage, packaging has been required to develop new capabilities to integrated MEMS and other technologies into functional microsystems. This paper discusses several of Sandia's MEMS packaging efforts, focusing mainly on inserting Sandia's SUMMIT V (5-level polysilicon) surface micromachining technology into fieldable microsystems.

  7. Idaho National Engineering Laboratory site development plan

    SciTech Connect

    Not Available

    1994-09-01

    This plan briefly describes the 20-year outlook for the Idaho National Engineering Laboratory (INEL). Missions, workloads, worker populations, facilities, land, and other resources necessary to fulfill the 20-year site development vision for the INEL are addressed. In addition, the plan examines factors that could enhance or deter new or expanded missions at the INEL. And finally, the plan discusses specific site development issues facing the INEL, possible solutions, resources required to resolve these issues, and the anticipated impacts if these issues remain unresolved.

  8. THE IDAHO NATIONAL LABORATORY BERYLLIUM TECHNOLOGY UPDATE

    SciTech Connect

    Glen R. Longhurst

    2007-12-01

    A Beryllium Technology Update meeting was held at the Idaho National Laboratory on July 18, 2007. Participants came from the U.S., Japan, and Russia. There were two main objectives of this meeting. One was a discussion of current technologies for beryllium in fission reactors, particularly the Advanced Test Reactor and the Japan Materials Test Reactor, and prospects for material availability in the coming years. The second objective of the meeting was a discussion of a project of the International Science and Technology Center regarding treatment of irradiated beryllium for disposal. This paper highlights discussions held during that meeting and major conclusions reached

  9. National Media Laboratory media testing results

    NASA Technical Reports Server (NTRS)

    Mularie, William

    1993-01-01

    The government faces a crisis in data storage, analysis, archive, and communication. The sheer quantity of data being poured into the government systems on a daily basis is overwhelming systems ability to capture, analyze, disseminate, and store critical information. Future systems requirements are even more formidable: with single government platforms having data rate of over 1 Gbit/sec, greater than Terabyte/day storage requirements, and with expected data archive lifetimes of over 10 years. The charter of the National Media Laboratory (NML) is to focus the resources of industry, government, and academia on government needs in the evaluation, development, and field support of advanced recording systems.

  10. Sandia National Laboratories approach to emergency preparedness

    SciTech Connect

    Galegar, F.H.; Yourick, P.D.; Ross, S.A.

    1997-12-31

    Sandia National Laboratories is located on Kirtland AFB on Albuquerque, NM. The Air Force Base proper covers about 74 square miles in which SNL maintains 5 technical areas and the Coyote Test Field. These SNL areas add up to about 18,000 acres. However, SNL has other locations where we conduct corporate emergency planning: Kauai Test Facility (at Pacific Missile Range Facility in Kauai, Hawaii), and the Tonopah Test Range (Nevada). SNL/California located in Livermore has an independent emergency preparedness organization for their emergency planning activities.

  11. Los Alamos National Laboratory computer benchmarking 1982

    SciTech Connect

    Martin, J.L.

    1983-06-01

    Evaluating the performance of computing machinery is a continual effort of the Computer Research and Applications Group of the Los Alamos National Laboratory. This report summarizes the results of the group's benchmarking activities performed between October 1981 and September 1982, presenting compilation and execution times as well as megaflop rates for a set of benchmark codes. Tests were performed on the following computers: Cray Research, Inc. (CRI) Cray-1S; Control Data Corporation (CDC) 7600, 6600, Cyber 73, Cyber 825, Cyber 835, Cyber 855, and Cyber 205; Digital Equipment Corporation (DEC) VAX 11/780 and VAX 11/782; and Apollo Computer, Inc., Apollo.

  12. Reference Materials and Reference Measurement Procedures: An Overview from a National Metrology Institute

    PubMed Central

    Bunk, David M

    2007-01-01

    An outline of the processes involved in both certified clinical reference material production and clinical reference measurement procedure development at the National Institute of Standards and Technology (NIST), the national metrology institute of the United States, is presented. The role that NIST and other national metrology institutes play in the metrological traceability of certified reference material is discussed. Highlighted are the challenges associated with the development of reference measurement systems for complex clinical analytes, such as proteins, and examples of existing efforts in this area are given. Examples of recent international collaborations in developing certified reference materials for analytes such as cardiac troponin I, brain natriuretic peptide, and serum creatinine demonstrate the close cooperation that national metrology institutes must have with the clinical community to establish complete reference measurement systems. PMID:18392127

  13. Lawrence Livermore National Laboratory Environmental Report 2015

    SciTech Connect

    Rosene, C. A.; Jones, H. E.

    2016-09-22

    The purposes of the Lawrence Livermore National Laboratory Environmental Report 2015 are to record Lawrence Livermore National Laboratory’s (LLNL’s) compliance with environmental standards and requirements, describe LLNL’s environmental protection and remediation programs, and present the results of environmental monitoring at the two LLNL sites—the Livermore Site and Site 300. The report is prepared for the U.S. Department of Energy (DOE) by LLNL’s Environmental Functional Area. Submittal of the report satisfies requirements under DOE Order 231.1B, “Environment, Safety and Health Reporting,” and DOE Order 458.1, “Radiation Protection of the Public and Environment.”

  14. Lawrence Livermore National Laboratory Environmental Report 2014

    SciTech Connect

    Jones, H. E.; Bertoldo, N. A.; Blake, R. G.; Buscheck, W. M.; Byrne, J. G.; Cerruti, S. J.; Bish, C. B.; Fratanduono, M. E.; Grayson, A. R.; MacQueen, D. H.; Montemayor, W. E.; Ottaway, H. L.; Paterson, L. E.; Revelli, M. A.; Rosene, C. A.; Swanson, K. A.; Terrill, A. A.; Wegrecki, A. M.; Wilson, K. R.; Woollett, J. S.

    2015-09-29

    The purposes of the Lawrence Livermore National Laboratory Environmental Report 2014 are to record Lawrence Livermore National Laboratory’s (LLNL’s) compliance with environmental standards and requirements, describe LLNL’s environmental protection and remediation programs, and present the results of environmental monitoring at the two LLNL sites—the Livermore Site and Site 300. The report is prepared for the U.S. Department of Energy (DOE) by LLNL’s Environmental Functional Area. Submittal of the report satisfies requirements under DOE Order 231.1B, “Environment, Safety and Health Reporting,” and DOE Order 458.1, “Radiation Protection of the Public and Environment.”

  15. Brookhaven National Laboratory site environmental report for calendar year 1994

    SciTech Connect

    Naidu, J.R.; Royce, B.A.

    1995-05-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and presents summary information about environmental compliance for 1994. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, groundwater, fauna and vegetation were made at the Brookhaven National Laboratory site and at sites adjacent to the Laboratory.

  16. National Environmental Policy Act (NEPA) Compliance Guide, Sandia National Laboratories

    SciTech Connect

    Hansen, R.P.

    1995-08-01

    This report contains a comprehensive National Environmental Policy Act (NEPA) Compliance Guide for the Sandia National Laboratories. It is based on the Council on Environmental Quality (CEQ) NEPA regulations in 40 CFR Parts 1500 through 1508; the US Department of Energy (DOE) N-EPA implementing procedures in 10 CFR Part 102 1; DOE Order 5440.1E; the DOE ``Secretarial Policy Statement on the National Environmental Policy Act`` of June 1994- Sandia NEPA compliance procedures-, and other CEQ and DOE guidance. The Guide includes step-by-step procedures for preparation of Environmental Checklists/Action Descriptions Memoranda (ECL/ADMs), Environmental Assessments (EAs), and Environmental Impact Statements (EISs). It also includes sections on ``Dealing With NEPA Documentation Problems`` and ``Special N-EPA Compliance Issues.``

  17. Los Alamos National Laboratory Building Cost Index

    SciTech Connect

    Orr, H.D.; Lemon, G.D.

    1983-01-01

    The Los Alamos National Laboratory Building Cost Index indicates that actual escalation since 1970 is near 10% per year. Therefore, the Laboratory will continue using a 10% per year escalation rate for construction estimates through 1985 and a slightly lower rate of 8% per year from 1986 through 1990. The computerized program compares the different elements involved in the cost of a typical construction project, which for our purposes, is a complex of office buildings and experimental laboratores. The input data used in the program consist primarily of labor costs and material and equipment costs. The labor costs are the contractural rates of the crafts workers in the Los Alamos area. For the analysis, 12 field-labor draft categories are used; each is weighted corresponding to the labor craft distribution associated with the typical construction project. The materials costs are current Los Alamos prices. Additional information sources include material and equipment quotes obtained through conversations with vendors and from trade publications. The material and equipment items separate into 17 categories for the analysis and are weighted corresponding to the material and equipment distribution associated with the typical construction project. The building cost index is compared to other national building cost indexes.

  18. Battery testing at Argonne National Laboratory

    NASA Astrophysics Data System (ADS)

    Deluca, W. H.; Gillie, K. R.; Kulaga, J. E.; Smaga, J. A.; Tummillo, A. F.; Webster, C. E.

    1993-03-01

    Argonne National Laboratory's Analysis & Diagnostic Laboratory (ADL) tests advanced batteries under simulated electric and hybrid vehicle operating conditions. The ADL facilities also include a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The battery evaluations and post-test examinations help identify factors that limit system performance and life and the most-promising R&D approaches for overcoming these limitations. Since 1991, performance characterizations and/or life evaluations have been conducted on eight battery technologies: Na/S, Li/S, Zn/Br, Ni/MH, Ni/Zn, Ni/Cd, Ni/Fe, and lead-acid. These evaluations were performed for the Department of Energy's. Office of Transportation Technologies, Electric and Hybrid Propulsion Division (DOE/OTT/EHP), and Electric Power Research Institute (EPRI) Transportation Program. The results obtained are discussed.

  19. Rapid prototyping applications at Sandia National Laboratories

    NASA Astrophysics Data System (ADS)

    Atwood, C. L.; McCarty, G. D.; Pardo, B. T.; Bryce, E. A.

    In an effort to reduce the cycle time for producing prototypical mechanical and electro-mechanical components, Sandia National Laboratories has integrated rapid prototyping processes into the design and manufacturing process. The processes currently in operation within the Rapid Prototyping Laboratory are Stereolithography (SL), Selective Laser Sintering (SLS), and Direct Shell Production Casting (DSPC). These emerging technologies have proven to be valuable tools for reducing lead times and fabrication costs. Sandia uses the SL and SLS processes to support internal product development efforts. Their primary use is to fabricate patterns for investment casting in support of a Sandia-managed program called FASTCAST that integrates computational technologies and experimental data into the investment casting process. These processes are also used in the design iteration process to produce proof-of-concept models, hands-on models for design reviews, fit-check models, visual aids for manufacturing, and functional parts in assemblies. The DSPC process is currently being developed as a method of fabricating ceramic investment casting molds directly from a CAD solid model. Sandia is an Alpha machine test site for this process. This presentation will provide an overview of the SL and SLS processes and an update of our experience and success in integrating these technologies into the product development cycle. It will also provide a lead-in for a tour of the Rapid Prototyping Laboratory, where these processes will be demonstrated.

  20. Rapid prototyping applications at Sandia National Laboratories

    SciTech Connect

    Atwood, C.L.; McCarty, G.D.; Pardo, B.T.; Bryce, E.A.

    1994-02-01

    In an effort to reduce the cycle time for producing prototypical mechanical and electro-mechanical components, Sandia National Laboratories has integrated rapid prototyping processes into the design and manufacturing process. The processes currently in operation within the Rapid Prototyping Laboratory are Stereolithography (SL), Selective Laser Sintering (SLS), and Direct Shell Production Casting (DSPC). These emerging technologies have proven to be valuable tools for reducing lead times and fabrication costs. Sandia uses the SL and SLS processes to support internal product development efforts. Their primary use is to fabricate patterns for investment casting in support of a Sandia-managed program called FASTCAST that integrates computational technologies and experimental data into the investment casting process. These processes are also used in the design iteration process to produce proof-of-concept models, hands-on models for design reviews, fit-check models, visual aids for manufacturing, and functional parts in assemblies. The DSPC process is currently being developed as a method of fabricating ceramic investment casting molds directly from a CAD solid model. Sandia is an Alpha machine test site for this process. This presentation will provide an overview of the SL and SLS processes and an update of our experience and success in integrating these technologies into the product development cycle. It will also provide a lead-in for a tour of the Rapid Prototyping Laboratory, where these processes will be demonstrated.

  1. Battery testing at Argonne National Laboratory

    SciTech Connect

    DeLuca, W.H.; Gillie, K.R.; Kulaga, J.E.; Smaga, J.A.; Tummillo, A.F.; Webster, C.E.

    1993-03-25

    Argonne National Laboratory's Analysis Diagnostic Laboratory (ADL) tests advanced batteries under simulated electric and hybrid vehicle operating conditions. The ADL facilities also include a post-test analysis laboratory to determine, in a protected atmosphere if needed, component compositional changes and failure mechanisms. The ADL provides a common basis for battery performance characterization and life evaluations with unbiased application of tests and analyses. The battery evaluations and post-test examinations help identify factors that limit system performance and life, and the most-promising R D approaches for overcoming these limitations. Since 1991, performance characterizations and/or life evaluations have been conducted on eight battery technologies (Na/S, Li/S, Zn/Br, Ni/MH, Ni/Zn, Ni/Cd, Ni/Fe, and lead-acid). These evaluations were performed for the Department of Energy's. Office of Transportation Technologies, Electric and Hybrid Propulsion Division (DOE/OTT/EHP), and Electric Power Research Institute (EPRI) Transportation Program. The results obtained are discussed.

  2. Dual-benefit technologies at Sandia National Laboratories

    SciTech Connect

    Schaefer, D.W.

    1993-12-31

    What does the pulp and paper industry have in common with the desert southwest and nuclear weapons? As a representative of one of the Nations three nuclear weapons design laboratories (Los Alamos National Laboratory, Livermore National Laboratory and Sandia National Laboratories), my goal is to identify ``dual-benefit`` technologies where codevelopment will both strengthen the nation`s competitive position and enhance national security. In development of this presentation, I found more common elements than I could possibly survey in this brief period.

  3. Proposals for ORNL (Oak Ridge National Laboratory) support to Tiber LLNL (Lawrence Livermore National Laboratory). [Engineering Test Reactor

    SciTech Connect

    Berry, L.A.; Rosenthal, M.W.; Saltmarsh, M.J.; Shannon, T.E.; Sheffield, J.

    1987-01-27

    This document describes the interests and capabilities of Oak Ridge National Laboratory in their proposals to support the Lawrence Livermore National Laboratory (LLNL) Engineering Test Reactor (ETR) project. Five individual proposals are cataloged separately. (FI)

  4. Risk management at Los Alamos National Laboratory

    SciTech Connect

    Brooks, D.G.; Stack, D.W.

    1993-11-01

    Los Alamos National Laboratory has risk management programs at a number of administrative levels. Each line organization has responsibility for risk management for routine operations. The Facility Risk Management group (HS-3) is the Los Alamos organization with the primary responsibility for risk management including providing input and expertise to facilities and line managers in the management and documentation of ES&H hazards and risks associated with existing and new activities. One of the major contributions this group has made to laboratory risk management program is to develop and implement a hazard identification and classification methodology that is readily adaptable to continuously changing classification guidelines such as DOE-STD-1027. The increased emphasis on safety at Los Alamos has led to the formation of additional safety oversight organization such as the Integration and Coordination Office (ICO), which is responsible for prioritization of risk management activities. In the fall of 1991, nearly 170 DOE inspectors spent 6 weeks analyzing the environmental, safety, and health activities at Los Alamos. The result of this audit was a list of over 1000 findings, each indicating some deficiency in current Laboratory operations relative to DOE and other government regulation. The audit team`s findings were consolidated and ``action plans`` were developed to address the findings. This resulted in over 200 action plans with a total estimated cost of almost $1 billion. The Laboratory adopted a risk-based prioritization process to attempt to achieve as much risk reduction as possible with the available resources. This paper describes the risk based prioritization model that was developed.

  5. Radiometric sources for the Los Alamos National Laboratory calibration Laboratory

    SciTech Connect

    Maier, W.B. II; Holland, R.; Bender, S.; Byrd, D.; Michaud, F.D.; Moore, S.; O`Brian, T.R.

    1994-07-01

    Los Alamos is developing a laboratory that will support state of the art calibration of moderate-aperture instrumentation (< 40 cm diameter) having high spatial and thermal resolution. Highly accurate calibration in the reflected solar and thermal infrared spectral regions are required for newly developed instrumentation. Radiometric calibration of the instrumentation requires well-characterized, extensive sources of radiation from 0.45 to 12 {mu}m. For wavelengths above 2.5 {mu}m, blackbodies having temperature control and radiometric uniformity to within 100 mK are being designed and will be radiometrically characterized at the National Institute of Standards and Technology (NIST). For the spectral range 0.45--2.5 {mu}m, a ``whitebody`` integrating sphere equipped with tungsten-halogen lamps and enclosed inside a vacuum shroud will be used; this vacuum-compatible extensive standard diffuse source utilizes well-known technology and will be characterized at NIST`s existing facilities. Characterization of instrumental contrast performance for wavelengths, {lambda}, beyond 2.5 {mu}m will utilize a recently designed absolute variable-contrast IR radiometric calibrator, and preliminary data indicate that this calibrator will perform satisfactorily. Conceptual design and status of these extensive broad-band sources and of a monochromatic source to be used for spectral calibrations will be presented.

  6. POLLUTION PREVENTION OPPORTUNITY ASSESSMENT - MANUFACTURING AND FABRICATION REPAIR LABORATORY AT SANDIA NATIONAL LABORATORIES

    EPA Science Inventory

    These reports summarize pollution prevention opportunity assessments conducted jointly by EPA and DOE at the Geochemistry Laboratory and the Manufacturing and Fabrication Repair Laboratory at the Department of Energy's Sandia National Laboratories facility in Albuquerque, New Mex...

  7. POLLUTION PREVENTION OPPORTUNITY ASSESSMENT - MANUFACTURING AND FABRICATION REPAIR LABORATORY AT SANDIA NATIONAL LABORATORIES

    EPA Science Inventory

    These reports summarize pollution prevention opportunity assessments conducted jointly by EPA and DOE at the Geochemistry Laboratory and the Manufacturing and Fabrication Repair Laboratory at the Department of Energy's Sandia National Laboratories facility in Albuquerque, New Mex...

  8. Future National Reference Frames for the United States

    NASA Astrophysics Data System (ADS)

    Stone, W. A.

    2015-12-01

    The mission of the National Oceanic and Atmospheric Administration's National Geodetic Survey (NGS) is "to define, maintain and provide access to the National Spatial Reference System (NSRS) to meet our nation's economic, social, and environmental needs." NSRS is the nation's system of latitude, longitude, elevation, and related geophysical and geodetic models and tools, which provides a consistent spatial reference framework for the broad spectrum of geoscientific applications and other positioning-related requirements. Technological developments - notably Global Navigation Satellite Systems (GNSS) - and user accuracy requirements necessitate that NGS endeavor to modernize the NSRS. Preparations are underway by NGS for a comprehensive NSRS makeover, to be completed in 2022 and delivered through a new generation of horizontal and vertical datums (reference frames), featuring unprecedented accuracy, repeatability, and efficiency of access. This evolution is outlined in the "National Geodetic Survey Ten-Year Strategic Plan, 2013-2023." This presentation will outline the motivation for this effort and the history, current status and planned evolution of NSRS. Fundamental to the delivery of the future reference frame paradigm are new geometric and geopotential (elevation) frameworks. The new geometric reference frame, realized through GNSS Continuously Operating Reference Stations (CORS), will replace the North American Datum of 1983 (NAD83) and will provide the nationwide framework for determination of latitude, longitude, and ellipsoid height. Designed to complement the new geometric reference frame, a corresponding geopotential reference frame - based on a national gravimetric geoid and replacing the North American Vertical Datum of 1988 (NAVD88) - will be developed and co-released. The gravimetric geoid - or definitional reference surface (zero elevation) - for the future geopotential reference frame will be built in part from airborne gravimetric data collected in

  9. Oak Ridge National Laboratory Technology Logic Diagram. Indexes

    SciTech Connect

    Not Available

    1993-09-01

    The Decontamination and Decommissioning (D&D) Index provides a comprehensive list of site problems, problem area/constituents, remedial technologies, and regulatory terms discussed in the D&D sections of the Oak Ridge National Laboratory Technology Logic Diagram. All entries provide specific page numbers, or cross-reference entries that provide specific page numbers, in the D&D volumes (Vol. 1, Pt. A; Vol. 2, Pt. A; and appropriate parts of Vol. 3). The Oak Ridge National Laboratory Technology (TLD) was developed to provide a decision-support tool that relates environmental restoration (ER) and waste management (WM) problems at Oak Ridge National Laboratory (ORNL) to potential technologies that can remediate these problems. The TLD identifies the research, development, demonstration, testing, and evaluation needed to develop these technologies to a state that allows technology transfer and application to decontamination and decommissioning (D&D), remedial action (RA) and WM activities. It is essential that follow-on engineering studies be conducted to build on the output of this project. These studies will begin by selecting the most promising technologies identified in the TLD and finding an optimum mix of technologies that will provide a socially acceptable balance between cost and risk.

  10. Oak Ridge National Laboratory Institutional Plan, FY 1995--FY 2000

    SciTech Connect

    Not Available

    1994-11-01

    This report discusses the institutional plan for Oak Ridge National Laboratory for the next five years (1995-2000). Included in this report are the: laboratory director`s statement; laboratory mission, vision, and core competencies; laboratory plan; major laboratory initiatives; scientific and technical programs; critical success factors; summaries of other plans; and resource projections.

  11. National voluntary laboratory accreditation program: Thermal insulation materials. Handbook

    SciTech Connect

    Knab, L.I.

    1995-05-01

    NIST Handbook 150-15 presents the technical requirements of the National Voluntary Laboratory Accreditation Program (NVLAP) for Thermal Insulation Materials. It is intended for information and use by staff of accredited laboratories, those laboratories seeking accreditation, other laboratory accreditation systems, users of laboratory services, and others needing information on the requirements for accreditation under the Thermal Insulation Materials program.

  12. [The role of reference laboratories in animal health programmes in South America].

    PubMed

    Bergmann, I E

    2003-08-01

    The contribution of the Panamerican Foot and Mouth Disease (FMD) Centre (PANAFTOSA), as an OIE (World organisation for animal health) regional reference laboratory for the diagnosis of FMD and vesicular stomatitis, and for the control of the FMD vaccine, has been of fundamental importance to the development, implementation and harmonisation of modern laboratory procedures in South America. The significance of the work conducted by PANAFTOSA is particularly obvious when one considers the two pillars on which eradication programmes are based, namely: a well-structured regional laboratory network, and the creation of a system which allows technology and new developments to be transferred to Member Countries as quickly and efficiently as possible. Over the past decade, PANAFTOSA has kept pace with the changing epidemiological situation on the continent, and with developments in the international political and economical situation. This has involved the strengthening of quality policies, and the elaboration and implementation of diagnostic tools that make for more thorough epidemiological analyses. The integration of PANAFTOSA into the network of national laboratories and its cooperation with technical and scientific institutes, universities and the private sector means that local needs can be met, thanks to the design and rapid implementation of methodological tools which are validated using internationally accepted criteria. This collaboration, which ensures harmonisation of laboratory tests and enhances the quality of national Veterinary Services, serves to promote greater equity, a prerequisite for regional eradication strategies and this in turn, helps to increase competitiveness in the region.

  13. Battery research at Argonne National Laboratory

    SciTech Connect

    Thackeray, M.M.

    1997-10-01

    Argonne National Laboratory (ANL) has, for many years, been engaged in battery-related R and D programs for DOE and the transportation industry. In particular, from 1973 to 1995, ANL played a pioneering role in the technological development of the high-temperature (400 C) lithium-iron disulfide battery. With the emphasis of battery research moving away from high temperature systems toward ambient temperature lithium-based systems for the longer term, ANL has redirected its efforts toward the development of a lithium-polymer battery (60--80 C operation) and room temperature systems based on lithium-ion technologies. ANL`s lithium-polymer battery program is supported by the US Advanced Battery Consortium (USABC), 3M and Hydro-Quebec, and the lithium-ion battery R and D efforts by US industry and by DOE.

  14. Solar activities at Sandia National Laboratories

    SciTech Connect

    Klimas, P.C.; Hasti, D.E.

    1994-03-01

    The use of renewable energy technologies is typically thought of as an integral part of creating and sustaining an environment that maximizes the overall quality of life of the Earth`s present inhabitants and does not leave an undue burden on future generations. Sandia National Laboratories has been a leader in developing and deploying many of these technologies over the last two decades. A common but special aspect of all of these activities is that they are all conducted in cooperation with various types of partners. Some of these partners have an interest in seeing these systems grow in the marketplace, while others are primarily concerned with economic benefits that can come from immediate use of these renewable energy systems. This paper describes solar thermal and photovoltaic technology activities at Sandia that are intended to accelerate the commercialization of these solar systems.

  15. Adaptive Optics at Lawrence Livermore National Laboratory

    SciTech Connect

    Gavel, D T

    2003-03-10

    Adaptive optics enables high resolution imaging through the atmospheric by correcting for the turbulent air's aberrations to the light waves passing through it. The Lawrence Livermore National Laboratory for a number of years has been at the forefront of applying adaptive optics technology to astronomy on the world's largest astronomical telescopes, in particular at the Keck 10-meter telescope on Mauna Kea, Hawaii. The technology includes the development of high-speed electrically driven deformable mirrors, high-speed low-noise CCD sensors, and real-time wavefront reconstruction and control hardware. Adaptive optics finds applications in many other areas where light beams pass through aberrating media and must be corrected to maintain diffraction-limited performance. We describe systems and results in astronomy, medicine (vision science), and horizontal path imaging, all active programs in our group.

  16. Idaho National Laboratory Environmental Monitoring Plan

    SciTech Connect

    Joanne L. Knight

    2008-04-01

    This plan describes environmental monitoring as required by U.S. Department of Energy (DOE) Order 450.1, “Environmental Protection Program,” and additional environmental monitoring currently performed by other organizations in and around the Idaho National Laboratory (INL). The objective of DOE Order 450.1 is to implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations. This plan describes the organizations responsible for conducting environmental monitoring across the INL, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. This plan presents a summary of the overall environmental monitoring performed in and around the INL without duplicating detailed information in the various monitoring procedures and program plans currently used to conduct monitoring.

  17. Idaho National Laboratory Quarterly Occurrence Analysis

    SciTech Connect

    Mitchell, Lisbeth Ann

    2015-11-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of 85 reportable events (18 from the 4th Qtr FY-15 and 67 from the prior three reporting quarters), as well as 25 other issue reports (including events found to be not reportable and Significant Category A and B conditions) identified at INL during the past 12 months (8 from this quarter and 17 from the prior three quarters).

  18. Idaho National Laboratory Quarterly Performance Analysis

    SciTech Connect

    Mitchell, Lisbeth

    2014-11-01

    This report is published quarterly by the Idaho National Laboratory (INL) Quality and Performance Management Organization. The Department of Energy (DOE) Occurrence Reporting and Processing System (ORPS), as prescribed in DOE Order 232.2, “Occurrence Reporting and Processing of Operations Information,” requires a quarterly analysis of events, both reportable and not reportable, for the previous 12 months. This report is the analysis of 60 reportable events (23 from the 4th Qtr FY14 and 37 from the prior three reporting quarters) as well as 58 other issue reports (including not reportable events and Significant Category A and B conditions) identified at INL from July 2013 through October 2014. Battelle Energy Alliance (BEA) operates the INL under contract DE AC07 051D14517.

  19. Idaho National Laboratory Site Environmental Monitoring Plan

    SciTech Connect

    Joanne L. Knight

    2010-10-01

    This plan describes environmental monitoring as required by U.S. Department of Energy (DOE) Order 450.1, “Environmental Protection Program,” and additional environmental monitoring currently performed by other organizations in and around the Idaho National Laboratory (INL). The objective of DOE Order 450.1 is to implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations. This plan describes the organizations responsible for conducting environmental monitoring across the INL, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. This plan presents a summary of the overall environmental monitoring performed in and around the INL without duplicating detailed information in the various monitoring procedures and program plans currently used to conduct monitoring.

  20. Fleet Tools; NREL (National Renewable Energy Laboratory)

    SciTech Connect

    2015-04-01

    From beverage distributors to shipping companies and federal agencies, industry leaders turn to the National Renewable Energy Laboratory (NREL) to help green their fleet operations. Cost, efficiency, and reliability are top priorities for fleets, and NREL partners know the lab’s portfolio of tools can pinpoint fuel efficiency and emissions-reduction strategies that also support operational the bottom line. NREL is one of the nation’s foremost leaders in medium- and heavy-duty vehicle research and development (R&D) and the go-to source for credible, validated transportation data. NREL developers have drawn on this expertise to create tools grounded in the real-world experiences of commercial and government fleets. Operators can use this comprehensive set of technology- and fuel-neutral tools to explore and analyze equipment and practices, energy-saving strategies, and other operational variables to ensure meaningful performance, financial, and environmental benefits.

  1. Los Alamos National Laboratory transuranic database analysis

    SciTech Connect

    Christensen, D.V.; Rogers, P.S.Z.; Kosiewicz, S.T.; LeBrun, D.B.

    1997-02-01

    This paper represents an overview of analyses conducted on the TRU database maintained by the Los Alamos National Laboratory (LANL). This evaluation was conducted to support the ``TRU Waste Workoff Strategies`` document and provides an estimation of the waste volume that potentially could be certified and ready for shipment to (WIPP) in April of 1998. Criteria defined in the WIPP WAC, including container type, weight limits, plutonium fissile gram equivalents and decay heat, were used to evaluated the waste for compliance. LANL evaluated the containers by facility and by waste stream to determining the most efficient plan for characterization and certification of the waste. Evaluation of the waste presently in storage suggested that 40- 60% potentially meets the WIPP WAC Rev. 5 criteria.

  2. Idaho National Laboratory Site Environmental Monitoring Plan

    SciTech Connect

    Joanne L. Knight

    2012-08-01

    This plan describes environmental monitoring as required by U.S. Department of Energy (DOE) Order 450.1, “Environmental Protection Program,” and additional environmental monitoring currently performed by other organizations in and around the Idaho National Laboratory (INL). The objective of DOE Order 450.1 is to implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations. This plan describes the organizations responsible for conducting environmental monitoring across the INL, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. This plan presents a summary of the overall environmental monitoring performed in and around the INL without duplicating detailed information in the various monitoring procedures and program plans currently used to conduct monitoring.

  3. SAVANNAH RIVER NATIONAL LABORATORY HYDROGEN TECHNOLOGY RESEARCH

    SciTech Connect

    Danko, E

    2008-02-08

    The Savannah River National Laboratory (SRNL) is a U.S. Department of Energy research and development laboratory located at the Savannah River Site (SRS) near Aiken, South Carolina. SRNL has over 50 years of experience in developing and applying hydrogen technology, both through its national defense activities as well as through its recent activities with the DOE Hydrogen Programs. The hydrogen technical staff at SRNL comprises over 90 scientists, engineers and technologists, and it is believed to be the largest such staff in the U.S. SRNL has ongoing R&D initiatives in a variety of hydrogen storage areas, including metal hydrides, complex hydrides, chemical hydrides and carbon nanotubes. SRNL has over 25 years of experience in metal hydrides and solid-state hydrogen storage research, development and demonstration. As part of its defense mission at SRS, SRNL developed, designed, demonstrated and provides ongoing technical support for the largest hydrogen processing facility in the world based on the integrated use of metal hydrides for hydrogen storage, separation, and compression. The SRNL has been active in teaming with academic and industrial partners to advance hydrogen technology. A primary focus of SRNL's R&D has been hydrogen storage using metal and complex hydrides. SRNL and its Hydrogen Technology Research Laboratory have been very successful in leveraging their defense infrastructure, capabilities and investments to help solve this country's energy problems. SRNL has participated in projects to convert public transit and utility vehicles for operation using hydrogen fuel. Two major projects include the H2Fuel Bus and an Industrial Fuel Cell Vehicle (IFCV) also known as the GATOR{trademark}. Both of these projects were funded by DOE and cost shared by industry. These are discussed further in Section 3.0, Demonstration Projects. In addition to metal hydrides technology, the SRNL Hydrogen group has done extensive R&D in other hydrogen technologies, including

  4. Idaho National Laboratory Site Environmental Monitoring Plan

    SciTech Connect

    Jenifer Nordstrom

    2014-02-01

    This plan provides a high-level summary of environmental monitoring performed by various organizations within and around the Idaho National Laboratory (INL) Site as required by U.S. Department of Energy (DOE) Order 435.1, Radioactive Waste Management, and DOE Order 458.1, Radiation Protection of the Public and the Environment, Guide DOE/EH-0173T, Environmental Regulatory Guide for Radiological Effluent Monitoring and Environmental Surveillance, and in accordance with 40 Code of Federal Regulations (CFR) 61, National Emission Standards for Hazardous Air Pollutants. The purpose of these orders is to 1) implement sound stewardship practices that protect the air, water, land, and other natural and cultural resources that may be impacted by DOE operations, and 2) to establish standards and requirements for the operations of DOE and DOE contractors with respect to protection of the environment and members of the public against undue risk from radiation. This plan describes the organizations responsible for conducting environmental monitoring across the INL Site, the rationale for monitoring, the types of media being monitored, where the monitoring is conducted, and where monitoring results can be obtained. Detailed monitoring procedures, program plans, or other governing documents used by contractors or agencies to implement requirements are referenced in this plan. This plan covers all planned monitoring and environmental surveillance. Nonroutine activities such as special research studies and characterization of individual sites for environmental restoration are outside the scope of this plan.

  5. Los Alamos National Laboratory Waste Management Program

    SciTech Connect

    Lopez-Escobedo, G.M.; Hargis, K.M.; Douglass, C.R.

    2007-07-01

    Los Alamos National Laboratory's (LANL) waste management program is responsible for disposition of waste generated by many of the LANL programs and operations. LANL generates liquid and solid waste that can include radioactive, hazardous, and other constituents. Where practical, LANL hazardous and mixed wastes are disposed through commercial vendors; low-level radioactive waste (LLW) and radioactive asbestos-contaminated waste are disposed on site at LANL's Area G disposal cells, transuranic (TRU) waste is disposed at the Waste Isolation Pilot Plant (WIPP), and high-activity mixed wastes are disposed at the Nevada Test Site (NTS) after treatment by commercial vendors. An on-site radioactive liquid waste treatment facility (RLWTF) removes the radioactive constituents from liquid wastes and treated water is released through an NPDES permitted outfall. LANL has a very successful waste minimization program. Routine hazardous waste generation has been reduced over 90% since 1993. LANL has a DOE Order 450.1-compliant environmental management system (EMS) that is ISO 14001 certified; waste minimization is integral to setting annual EMS improvement objectives. Looking forward, under the new LANL management and operating contractor, Los Alamos National Security (LANS) LLC, a Zero Liquid Discharge initiative is being planned that should eliminate flow to the RLWTF NPDES-permitted outfall. The new contractor is also taking action to reduce the number of permitted waste storage areas, to charge generating programs directly for the cost to disposition waste, and to simplify/streamline the waste system. (authors)

  6. Opportunities and Challenges for Women in Physics in National Laboratories

    NASA Astrophysics Data System (ADS)

    Karplus Hartline, Beverly

    2010-02-01

    America's national laboratories have long been major players advancing science and technology, especially in physics and engineering. Both true government laboratories, like the National Institute of Standards and Technology (NIST), Naval Research Laboratory, and National Aeronautics and Space Administration (NASA), and contractor-operated laboratories, like most of the Department of Energy (DOE) laboratories, employ large numbers of physicists---mostly men, but increasing numbers of women. Among them are former astronaut Sally Ride, APS' 2009 President Cherry Murray, Nobel laureate Maria Goeppert Mayer, Leona Woods Marshall Libby, Elaine Oran, and Deborah Jin. Research at national laboratories also involve numerous high-school, undergraduate, and graduate students, along with post-doctoral fellows, thereby helping to launch many into physics careers. This presentation will discuss the opportunities, challenges, and climate for women in physics at national laboratories, from the perspective of a person with about 20 years experience as a researcher and manager at both NASA and DOE laboratories. )

  7. Technical Assistance Guide: Working with DOE National Laboratories (Brochure)

    SciTech Connect

    Not Available

    2012-07-01

    A fact sheet that provides an overview of FEMP's technical assistance through the Department of Energy's National Laboratories. The Federal Energy Management Program (FEMP) facilitates the Federal Government's implementation of sound, cost-effective energy management and investment practices to enhance the nation's energy security and environmental stewardship. To advance that mission, FEMP fosters collaboration between Federal agencies and U.S. Department of Energy (DOE) national laboratories. This guide outlines technical assistance capabilities and expertise at DOE national laboratories. Any laboratory assistance must be in accordance with Federal Acquisition Regulation (FAR) Subpart 35.017 requirements and the laboratory's designation as Federal Funded Research and Development Center (FFRDC) facilities.

  8. Brookhaven National Laboratory site environmental report for calendar year 1996

    SciTech Connect

    Schroeder, G.L.; Paquette, D.E.; Naidu, J.R.; Lee, R.J.; Briggs, S.L.K.

    1998-01-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and summarizes information about environmental compliance for 1996. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and of a variety of radionuclides and chemical compounds in the ambient air, soil, sewage effluent, surface water, groundwater, fauna, and vegetation were made at the Brookhaven National Laboratory site and at adjacent sites. The report also evaluates the Laboratory`s compliance with all applicable guides, standards, and limits for radiological and non-radiological emissions and effluents to the environment.

  9. Brook trout nutritional analysis for inclusion into the USDA National Nutrient Database for Standard Reference

    USDA-ARS?s Scientific Manuscript database

    Many species of wild game and fish that are legal to hunt or catch do not have nutrition information in the USDA National Nutrient Database for Standard Reference (SR). Among those species that lack nutrition information are brook trout. The research team worked with the Nutrient Data Laboratory wit...

  10. Power source evaluation capabilities at Sandia National Laboratories

    SciTech Connect

    Doughty, D.H.; Butler, P.C.

    1996-04-01

    Sandia National Laboratories maintains one of the most comprehensive power source characterization facilities in the U.S. National Laboratory system. This paper describes the capabilities for evaluation of fuel cell technologies. The facility has a rechargeable battery test laboratory and a test area for performing nondestructive and functional computer-controlled testing of cells and batteries.

  11. Laboratory Reference Spectroscopy of Icy Satellite Candidate Surface Materials (Invited)

    NASA Astrophysics Data System (ADS)

    Dalton, J. B.; Jamieson, C. S.; Shirley, J. H.; Pitman, K. M.; Kariya, M.; Crandall, P.

    2013-12-01

    The bulk of our knowledge of icy satellite composition continues to be derived from ultraviolet, visible and infrared remote sensing observations. Interpretation of remote sensing observations relies on availability of laboratory reference spectra of candidate surface materials. These are compared directly to observations, or incorporated into models to generate synthetic spectra representing mixtures of the candidate materials. Spectral measurements for the study of icy satellites must be taken under appropriate conditions (cf. Dalton, 2010; also http://mos.seti.org/icyworldspectra.html for a database of compounds) of temperature (typically 50 to 150 K), pressure (from 10-9 to 10-3 Torr), viewing geometry, (i.e., reflectance), and optical depth (must manifest near infrared bands but avoid saturation in the mid-infrared fundamentals). The Planetary Ice Characterization Laboratory (PICL) is being developed at JPL to provide robust reference spectra for icy satellite surface materials. These include sulfate hydrates, hydrated and hydroxylated minerals, and both organic and inorganic volatile ices. Spectral measurements are performed using an Analytical Spectral Devices FR3 portable grating spectrometer from .35 to 2.5 microns, and a Thermo-Nicolet 6500 Fourier-Transform InfraRed (FTIR) spectrometer from 1.25 to 20 microns. These are interfaced with the Basic Extraterrestrial Environment Simulation Testbed (BEEST), a vacuum chamber capable of pressures below 10-9 Torr with a closed loop liquid helium cryostat with custom heating element capable of temperatures from 30-800 Kelvins. To generate optical constants (real and imaginary index of refraction) for use in nonlinear mixing models (i.e., Hapke, 1981 and Shkuratov, 1999), samples are ground and sieved to six different size fractions or deposited at varying rates to provide a range of grain sizes for optical constants calculations based on subtractive Kramers-Kronig combined with Hapke forward modeling (Dalton and

  12. Oak Ridge National Laboratory institutional plan, FY 1996--FY 2001

    SciTech Connect

    1995-12-01

    This report discusses the institutional plan for Oak Ridge National Laboratory for the next five years. Included in the report are: laboratory director`s statement; laboratory mission, vision, and core competencies; laboratory strategic plan; major laboratory initiatives; scientific and technical programs; critical success factors; summaries of other plans; resource projections; appendix which contains data for site and facilities, user facility, science and mathematic education and human resources; and laboratory organization chart.

  13. The Role of a National Biocontainment Laboratory in Emergencies.

    PubMed

    Le Duc, James W; Ksiazek, Thomas G

    2015-01-01

    Over a decade ago, the National Institutes of Health awarded partial support for the construction and operation of 2 National Biocontainment Laboratories, with the condition that they would be available to assist in the event of public health emergencies-although how a biocontainment facility located on an academic campus might contribute was not defined. Here we offer examples of how one of these laboratories has contributed to a coordinated response to 2 recent international public health emergencies. Essential assets for success include highly trained and experienced staff, access to reference pathogens and reagents, cutting-edge knowledge of the field, appropriate biocontainment facilities, robust biosafety and biosecurity programs, and availability of modern instrumentation. The ability to marry the strengths of academia in basic and applied research with access to appropriate biocontainment facilities while drawing on a highly skilled cadre of experienced experts has proven extremely valuable in the response to recent national emergencies and will continue to do so in the future. Areas where additional planning and preparation are needed have also been identified through these experiences.

  14. Biosafety Practices and Emergency Response at the Idaho National Laboratory and Los Alamos National Laboratory

    SciTech Connect

    Frank F. Roberto; Dina M. Matz

    2008-03-01

    Strict federal regulations govern the possession, use, and transfer of pathogens and toxins with potential to cause harm to the public, either through accidental or deliberate means. Laboratories registered through either the Centers for Disease Control and Prevention (CDC), the U.S. Dept. of Agriculture (USDA), or both, must prepare biosafety, security, and incident response plans, conduct drills or exercises on an annual basis, and update plans accordingly. At the Idaho National Laboratory (INL), biosafety, laboratory, and emergency management staff have been working together for 2 years to satisfy federal and DOE/NNSA requirements. This has been done through the establishment of plans, training, tabletop and walk-through exercises and drills, and coordination with local and regional emergency response personnel. Responding to the release of infectious agents or toxins is challenging, but through familiarization with the nature of the hazardous biological substances or organisms, and integration with laboratory-wide emergency response procedures, credible scenarios are being used to evaluate our ability to protect workers, the public, and the environment from agents we must work with to provide for national biodefense.

  15. Los Alamos National Laboratory Prepares for Fire Season

    SciTech Connect

    L’Esperance, Manny

    2016-07-18

    Through the establishment of a Wildland Fire Program Office, and the Interagency Fire Base located on Laboratory property, Los Alamos National Laboratory is continuing and improving a program to prepare for wildland fire.

  16. Los Alamos National Laboratory Prepares for Fire Season

    ScienceCinema

    L’Esperance, Manny

    2016-08-10

    Through the establishment of a Wildland Fire Program Office, and the Interagency Fire Base located on Laboratory property, Los Alamos National Laboratory is continuing and improving a program to prepare for wildland fire.

  17. Transportation Deployment; NREL (National Renewable Energy Laboratory)

    SciTech Connect

    2015-06-01

    Automakers, commercial fleet operators, component manufacturers, and government agencies all turn to the U.S. Department of Energy’s National Renewable Energy Laboratory (NREL) to help put more green vehicles on the road. The lab’s independent analysis and evaluation pinpoint fuel-efficient and low-emission strategies to support economic and operational goals, while breaking down barriers to widespread adoption. Customized assessment of existing equipment and practices, energy-saving alternatives, operational considerations, and marketplace realities factor in the multitude of variables needed to ensure meaningful performance, financial, and environmental benefits. NREL provides integrated, unbiased, 360-degree sustainable transportation deployment expertise encompassing alternative fuels, advanced vehicles, and related infrastructure. Hands-on support comes from technical experts experienced in advanced vehicle technologies, fleet operations, and field data collection coupled with extensive modeling and analysis capabilities. The lab’s research team works closely with automakers and vehicle equipment manufacturers to test, analyze, develop, and evaluate high-performance fuel-efficient technologies that meet marketplace needs.

  18. Nanosatellite program at Sandia National Laboratories

    SciTech Connect

    Reynolds, D.A.; Kern, J.P.; Schoeneman, J.L.

    1999-11-11

    The concept of building extremely small satellites which, either independently or as a collective, can perform missions which are comparable to their much larger cousins, has fascinated scientists and engineers for several years now. In addition to the now commonplace microelectronic integrated circuits, the more recent advent of technologies such as photonic integrated circuits (PIC's) and micro-electromechanical systems (MEMS) have placed such a goal within their grasp. Key to the acceptance of this technology will be the ability to manufacture these very small satellites in quantity without sacrificing their performance or versatility. In support of its nuclear treaty verification, proliferation monitoring and other remote sensing missions, Sandia National laboratories has had a 35-year history of providing highly capable systems, densely packaged for unintrusive piggyback missions on government satellites. As monitoring requirements have become more challenging and remote sensing technologies become more sophisticated, packaging greater capability into these systems has become a requirement. Likewise, dwindling budgets are pushing satellite programs toward smaller and smaller platforms, reinforcing the need for smaller, cheaper satellite systems. In the next step of its miniaturization plan, Sandia has begun development of technologies for a highly integrated miniature satellite. The focus of this development is to achieve nanosat or smaller dimensions while maintaining significant capability utilizing semiconductor wafer-level integration and, at the same time promoting affordability through modular generic construction.

  19. Geothermal materials development at Brookhaven National Laboratory

    SciTech Connect

    Kukacka, L.E.

    1997-12-31

    As part of the DOE/OGT response to recommendations and priorities established by industrial review of their overall R&D program, the Geothermal Materials Program at Brookhaven National Laboratory (BNL) is focusing on topics that can reduce O&M costs and increase competitiveness in foreign and domestic markets. Corrosion and scale control, well completion materials, and lost circulation control have high priorities. The first two topics are included in FY 1997 BNL activities, but work on lost circulation materials is constrained by budgetary limitations. The R&D, most of which is performed as cost-shared efforts with U.S. geothermal firms, is rapidly moving into field testing phases. FY 1996 and 1997 accomplishments in the development of lightweight CO{sub 2}-resistant cements for well completions; corrosion resistant, thermally conductive polymer matrix composites for heat exchange applications; and metallic, polymer and ceramic-based corrosion protective coatings are given in this paper. In addition, plans for work that commenced in March 1997 on thermally conductive cementitious grouting materials for use with geothermal heat pumps (GHP), are discussed.

  20. Sandia National Laboratories Medical Isotope Reactor concept.

    SciTech Connect

    Coats, Richard Lee; Dahl, James J.; Parma, Edward J., Jr.

    2010-04-01

    This report describes the Sandia National Laboratories Medical Isotope Reactor and hot cell facility concepts. The reactor proposed is designed to be capable of producing 100% of the U.S. demand for the medical isotope {sup 99}Mo. The concept is novel in that the fuel for the reactor and the targets for the {sup 99}Mo production are the same. There is no driver core required. The fuel pins that are in the reactor core are processed on a 7 to 21 day irradiation cycle. The fuel is low enriched uranium oxide enriched to less than 20% {sup 235}U. The fuel pins are approximately 1 cm in diameter and 30 to 40 cm in height, clad with Zircaloy (zirconium alloy). Approximately 90 to 150 fuel pins are arranged in the core in a water pool {approx}30 ft deep. The reactor power level is 1 to 2 MW. The reactor concept is a simple design that is passively safe and maintains negative reactivity coefficients. The total radionuclide inventory in the reactor core is minimized since the fuel/target pins are removed and processed after 7 to 21 days. The fuel fabrication, reactor design and operation, and {sup 99}Mo production processing use well-developed technologies that minimize the technological and licensing risks. There are no impediments that prevent this type of reactor, along with its collocated hot cell facility, from being designed, fabricated, and licensed today.

  1. Geothermal materials development at Brookhaven National Laboratory

    SciTech Connect

    Kukacka, L.E.

    1997-06-01

    As part of the DOE/OGT response to recommendations and priorities established by industrial review of their overall R and D program, the Geothermal Materials Program at Brookhaven National Laboratory (BNL) is focusing on topics that can reduce O and M costs and increase competitiveness in foreign and domestic markets. Corrosion and scale control, well completion materials, and lost circulation control have high priorities. The first two topics are included in FY 1997 BNL activities, but work on lost circulation materials is constrained by budgetary limitations. The R and D, most of which is performed as cost-shared efforts with US geothermal firms, is rapidly moving into field testing phases. FY 1996 and 1997 accomplishments in the development of lightweight CO{sub 2}-resistant cements for well completions; corrosion resistant, thermally conductive polymer matrix composites for heat exchange applications; and metallic, polymer and ceramic-based corrosion protective coatings are given in this paper. In addition, plans for work that commenced in March 1997 on thermally conductive cementitious grouting materials for use with geothermal heat pumps (GHP), are discussed.

  2. Instrumentation and telemetry at Sandia National Laboratories.

    SciTech Connect

    Not Available

    1992-01-01

    Sandia National Laboratories (SNL) is a Department of Energy multiprogram engineering and scientific facility with unique design, development, and test capabilities arising from their work in nuclear weapons, energy resources, defense systems, nuclear safeguards, and specialized scientific endeavors. To support these programs, they have developed instrumentation and telemetry expertise not available elsewhere. This technology is applicable to projects in government and industry. Since the 1950s, they have applied our technical competence to meet difficult challenges with innovative solutions to data acquisition and telemetry problems. Sandia - with experience in fields as diverse as parachute design and plasma physics, geology and rocket guidance, human factors and high-speed aerodynamics, non-destructive testing and satellite communications - can use the power of synergism among our many disciplines to solve your complex problems of data and acquisition and analysis. SNL solves difficult data acquisition problems for extreme environments with expertise in advanced telemetry techniques, high data rate telemetry design, specialized electronics packaging, MIL-STD-1553 communications, instrumentation development, real-time data analysis, project management, specialized testers and data encryption.

  3. Evaluation of molecular typing of foodborne pathogens in European reference laboratories from 2012 to 2013.

    PubMed

    Schjørring, Susanne; Niskanen, Taina; Torpdahl, Mia; Björkman, Jonas T; Nielsen, Eva Møller

    2016-12-15

    In 2012, the European Centre for Disease Prevention and Control (ECDC) initiated external quality assessment (EQA) schemes for molecular typing including the National Public Health Reference Laboratories in Europe. The overall aim for these EQA schemes was to enhance the European surveillance of food-borne pathogens by evaluating and improving the quality and comparability of molecular typing. The EQAs were organised by Statens Serum Institut (SSI) and included Salmonella enterica subsp. enterica, verocytotoxin-producing Escherichia coli (VTEC) and Listeria monocytogenes. Inter-laboratory comparable pulsed-field gel electrophoresis (PFGE) images were obtained from 10 of 17 of the participating laboratories for Listeria, 15 of 25 for Salmonella, but only nine of 20 for VTEC. Most problems were related to PFGE running conditions and/or incorrect use of image acquisition. Analysis of the gels was done in good accordance with the provided guidelines. Furthermore, we assessed the multilocus variable-number tandem repeat analysis (MLVA) scheme for S. Typhimurium. Of 15 laboratories, nine submitted correct results for all analysed strains, and four had difficulties with one strain only. In conclusion, both PFGE and MLVA are prone to variation in quality, and there is therefore a continuous need for standardisation and validation of laboratory performance for molecular typing methods of food-borne pathogens in the human public health sector. This article is copyright of The Authors, 2016.

  4. Evaluation of molecular typing of foodborne pathogens in European reference laboratories from 2012 to 2013

    PubMed Central

    Schjørring, Susanne; Niskanen, Taina; Torpdahl, Mia; Björkman, Jonas T; Nielsen, Eva Møller

    2016-01-01

    In 2012, the European Centre for Disease Prevention and Control (ECDC) initiated external quality assessment (EQA) schemes for molecular typing including the National Public Health Reference Laboratories in Europe. The overall aim for these EQA schemes was to enhance the European surveillance of food-borne pathogens by evaluating and improving the quality and comparability of molecular typing. The EQAs were organised by Statens Serum Institut (SSI) and included Salmonella enterica subsp. enterica, verocytotoxin-producing Escherichia coli (VTEC) and Listeria monocytogenes. Inter-laboratory comparable pulsed-field gel electrophoresis (PFGE) images were obtained from 10 of 17 of the participating laboratories for Listeria, 15 of 25 for Salmonella, but only nine of 20 for VTEC. Most problems were related to PFGE running conditions and/or incorrect use of image acquisition. Analysis of the gels was done in good accordance with the provided guidelines. Furthermore, we assessed the multilocus variable-number tandem repeat analysis (MLVA) scheme for S. Typhimurium. Of 15 laboratories, nine submitted correct results for all analysed strains, and four had difficulties with one strain only. In conclusion, both PFGE and MLVA are prone to variation in quality, and there is therefore a continuous need for standardisation and validation of laboratory performance for molecular typing methods of food-borne pathogens in the human public health sector. PMID:28006653

  5. National Vehicle and Fuel Emissions Laboratory (NVFEL)

    EPA Pesticide Factsheets

    NVFEL is the primary EPA research laboratory used for fuel and emissions testing. The laboratory supports emission standards for motor vehicles, engines, and fuels, as well as the development of automotive technology.

  6. Partnering at the National Laboratories: Catalysis as a Case Study

    SciTech Connect

    JACKSON,NANCY B.

    1999-09-14

    The role of the national laboratories, particularly the defense program laboratories, since the end of the cold war, has been a topic of continuing debate. The relationship of national laboratories to industry spurred debate which ranged from designating the labs as instrumental to maintaining U.S. economic competitiveness to concern over the perception of corporate welfare to questions regarding the industrial globalization and the possibility of U.S. taxpayer dollars supporting foreign entities. Less debated, but equally important, has been the national laboratories' potential competition with academia for federal research dollars and discussions detailing the role of each in the national research enterprise.

  7. Final Report National Laboratory Professional Development Workshop for Underrepresented Participants

    SciTech Connect

    Taylor, Valerie

    2016-11-07

    The 2013 CMD-IT National Laboratories Professional Development Workshop for Underrepresented Participants (CMD-IT NLPDev 2013) was held at the Oak Ridge National Laboratory campus in Oak Ridge, TN. from June 13 - 14, 2013. Sponsored by the Department of Energy (DOE) Advanced Scientific Computing Research Program, the primary goal of these workshops is to provide information about career opportunities in computational science at the various national laboratories and to mentor the underrepresented participants through community building and expert presentations focused on career success. This second annual workshop offered sessions to facilitate career advancement and, in particular, the strategies and resources needed to be successful at the national laboratories.

  8. Idaho National Laboratory Mission Accomplishments, Fiscal Year 2015

    SciTech Connect

    Allen, Todd Randall; Wright, Virginia Latta

    2015-09-01

    A summary of mission accomplishments for the research organizations at the Idaho National Laboratory for FY 2015. Areas include Nuclear Energy, National and Homeland Security, Science and Technology Addressing Broad DOE Missions; Collaborations; and Stewardship and Operation of Research Facilities.

  9. Technical Assistance Guide: Working with DOE National Laboratories (Brochure)

    SciTech Connect

    Not Available

    2010-06-01

    Guide to inform agencies of the capabilities and expertise of DOE national laboratories, as well as process and contacts for Federal agencies to enter work for others agreements with DOE national labs.

  10. 76 FR 17367 - National Voluntary Laboratory Accreditation Program; Operating Procedures

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-29

    ... Accreditation Program; Operating Procedures AGENCY: National Institute of Standards and Technology (NIST... National Institute of Standards and Technology (NIST), United States Department of Commerce, requests... Laboratory Accreditation Program (NVLAP). NIST proposes to revise the description of how NVLAP establishes...

  11. Idaho National Engineering Laboratory: Annual report, 1986

    SciTech Connect

    Not Available

    1986-01-01

    The INEL underwent a year of transition in 1986. Success with new business initiatives, the prospects of even better things to come, and increased national recognition provided the INEL with a glimpse of its promising and exciting future. Among the highlights were: selection of the INEL as the preferred site for the Special Isotope Separation Facility (SIS); the first shipments of core debris from the Three Mile Island Unit 2 reactor to the INEL; dedication of three new facilities - the Fluorinel Dissolution Process, the Remote Analytical Laboratory, and the Stored Waste Experimental Pilot Plant; groundbreaking for the Fuel Processing Restoration Facility; and the first IR-100 award won by the INEL, given for an innovative machine vision system. The INEL has been assigned project management responsibility for the SDI Office-sponsored Multimegawatt Space Reactor and the Air Force-sponsored Multimegawatt Terrestrial Power Plant Project. New Department of Defense initiatives have been realized in projects involving development of prototype defense electronics systems, materials research, and hazardous waste technology. While some of our major reactor safety research programs have been completed, the INEL continues as a leader in advanced reactor technologies development. In April, successful tests were conducted for the development of the Integral Fast Reactor. Other 1986 highlights included the INEL's increased support to the Office of Civilian Radioactive Waste Management for complying with the Nuclear Waste Policy Act of 1982. Major INEL activities included managing a cask procurement program, demonstrating fuel assembly consolidation, and testing spent fuel storage casks. In addition, the INEL supplied the Tennessee Valley Authority with management and personnel experienced in reactor technology, increased basic research programs at the Idaho Research Center, and made numerous outreach efforts to assist the economies of Idaho communities.

  12. Robot safety training at Lawrence Livermore National Laboratory

    SciTech Connect

    McMahon, T.T.; Sievers, R.H.

    1992-10-01

    The Lawrence Livermore National Laboratory (LLNL) is developing applications of commercially available and advanced robotics. These involve multiple installations of test and demonstration robots and extensive concurrent research and development projects. LLNL robotic applications use many researchers and technicians requiring access to the equipment on tight schedules, using sophisticated support and auxiliary equipment, with concurrent programming and hardware installation and modification. The early recognition of the special safety problems inherent with the equipment and development operations mandated a strict compliance with the best available safety guidance. This has resulted in safety input in the system design, equipment layout, means of safeguarding, and safety training as described in the current and proposed American National Standard for Industrial Robots and Robot Systems-Safety Requirements. LLNL has implemented a model robot safety training program that is required for all employees that interact with the fixed robotic systems. The LLNL experience and performance has led to the Laboratory being made responsible for preparation of the industrial robots safety chapter for the Department of Energy Technical Safety Reference Manual. This paper describes the robotic installations, the safety training courses, lessons learned from the training, and recommendations for future robot safety training.

  13. Environmental monitoring at Argonne National Laboratory. Annual report for 1983

    SciTech Connect

    Golchert, N.W.; Duffy, T.L.; Sedlet, J.

    1984-03-01

    The results of the environmental monitoring program at Argonne National Laboratory for 1983 are presented and discussed. To evaluate the effect of Argonne operations on the environment, measurements were made for a variety of radionuclides in air, surface water, soil, grass, bottom sediment, and milk; for a variety of chemical constituents in air, surface water, ground water, and Argonne effluent water; and of the environmental penetrating radiation dose. Sample collections and measurements were made at the site boundary and off the Argonne site for comparison purposes. Some on-site measurements were made to aid in the interpretation of the boundary and off-site data. The potential radiation dose to off-site population groups is also estimated. The results of the program are interpreted in terms of the sources and origin of the radioactive and chemical substances (natural, fallout, Argonne, and other) and are compared with applicable environmental quality standards. 19 references, 8 figures, 49 tables.

  14. Summary of failure analysis activities at Brookhaven National Laboratory

    SciTech Connect

    Cowgill, M.G.; Czajkowski, C.J.; Franz, E.M.

    1996-10-01

    Brookhaven National Laboratory has for many years conducted examinations related to the failures of nuclear materials and components. These examinations included the confirmation of root cause analyses, the determination of the causes of failure, identification of the species that accelerate corrosion, and comparison of the results of nondestructive examinations with those obtained by destructive examination. The results of those examinations, which had previously appeared in various formats (formal and informal reports, journal articles, etc.), have been collected together and summarized in the present report. The report is divided into sections according to the general subject matter (for example, corrosion, fatigue, etc.). Each section presents summaries of the information contained in specific reports and publications, all of which are fully identified as to title, authors, report number or journal reference, date of publication, and FIN number under which the work was performed.

  15. 60 Years of Great Science (Oak Ridge National Laboratory)

    DOE R&D Accomplishments Database

    2003-01-01

    This issue of Oak Ridge National Laboratory Review (vol. 36, issue 1) highlights Oak Ridge National Laboratory's contributions in more than 30 areas of research and related activities during the past 60 years and provides glimpses of current activities that are carrying on this heritage.

  16. Annual Report on the State of the DOE National Laboratories

    SciTech Connect

    2017-01-01

    This first Annual Report to Congress on the State of the DOE National Laboratories provides a comprehensive overview of the Lab system, covering S&T programs, management and strategic planning. The Department committed to prepare this report in response to recommendations from the Congressionally mandated Commission to Review the Effectiveness of the National Energy Laboratories (CRENEL) that the Department should better communicate the value that the Laboratories provide to the Nation. We expect that future annual reports will be much more compact, building on the extensive description of the Laboratories and of the governance structures that are part of this first report.

  17. National Bio-fuel Energy Laboratory

    SciTech Connect

    Jezierski, Kelly

    2010-12-27

    The National Biofuel Energy Laboratory or NBEL was a consortia consisting of non-profits, universities, industry, and OEM’s. NextEnergy Center (NEC) in Detroit, Michigan was the prime with Wayne State University as the primary subcontractor. Other partners included: Art Van Furniture; Biodiesel Industries Inc. (BDI); Bosch; Clean Emission Fluids (CEF); Delphi; Oakland University; U.S. TARDEC (The Army); and later Cummins Bridgeway. The program was awarded to NextEnergy by U.S. DOE-NREL on July 1, 2005. The period of performance was about five (5) years, ending June 30, 2010. This program was executed in two phases: 1.Phase I focused on bench-scale R&D and performance-property-relationships. 2.Phase II expanded those efforts into further engine testing, emissions testing, and on-road fleet testing of biodiesel using additional types of feedstock (i.e., corn, and choice white grease based). NextEnergy – a non-profit 501(c)(3) organization based in Detroit was originally awarded a $1.9 million grant from the U.S. Dept. of Energy for Phase I of the NBEL program. A few years later, NextEnergy and its partners received an additional $1.9MM in DOE funding to complete Phase II. The NBEL funding was completely exhausted by the program end date of June 30, 2010 and the cost share commitment of 20% minimum has been exceeded nearly two times over. As a result of the work performed by the NBEL consortia, the following successes were realized: 1.Over one hundred publications and presentations have been delivered by the NBEL consortia, including but not limited to: R&D efforts on algae-based biodiesel, novel heterogeneous catalysis, biodiesel properties from a vast array of feedstock blends, cold flow properties, engine testing results (several Society of Automotive Engineers [SAE] papers have been published on this research), emissions testing results, and market quality survey results. 2.One new spinoff company (NextCAT) was formed by two WSU Chemical Engineering professors

  18. Californium Electrodepositions at Oak Ridge National Laboratory

    SciTech Connect

    Boll, Rose Ann

    2015-01-01

    Electrodepositions of californium isotopes were successfully performed at Oak Ridge National Laboratory (ORNL) during the past year involving two different types of deposition solutions, ammonium acetate (NH4C2H3O2) and isobutanol ((CH3)2CHCH2OH). A californium product that was decay enriched in 251Cf was recovered for use in super-heavy element (SHE) research. This neutron-rich isotope, 251Cf, provides target material for SHE research for the potential discovery of heavier isotopes of Z=118. The californium material was recovered from aged 252Cf neutron sources in storage at ORNL. These sources have decayed for over 30 years, thus providing material with a very high 251Cf-to-252Cf ratio. After the source capsules were opened, the californium was purified and then electrodeposited using the isobutanol method onto thin titanium foils for use in an accelerator at the Joint Institute for Nuclear Research in Dubna, Russia. Another deposition method, ammonium acetate, was used to produce a deposition containing 1.7 0.1 Ci of 252Cf onto a stainless steel substrate. This was the largest single electrodeposition of 252Cf ever prepared. The 252Cf material was initially purified using traditional ion exchange media, such as AG50-AHIB and AG50-HCl, and further purified using a TEVA-NH4SCN system to remove any lanthanides, resulting in the recovery of 3.6 0.1 mg of purified 252Cf. The ammonium acetate deposition was run with a current of 1.0 amp, resulting in a 91.5% deposition yield. Purification and handling of the highly radioactive californium material created additional challenges in the production of these sources.

  19. Idaho National Laboratory Site Pollution Prevention Plan

    SciTech Connect

    E. D. Sellers

    2007-03-01

    It is the policy of the Department of Energy (DOE) that pollution prevention and sustainable environmental stewardship will be integrated into DOE operations as a good business practice to reduce environmental hazards, protect environmental resources, avoid pollution control costs, and improve operational efficiency and mission sustainability. In furtherance of this policy, DOE established five strategic, performance-based Pollution Prevention (P2) and Sustainable Environmental Stewardship goals and included them as an attachment to DOE O 450.1, Environmental Protection Program. These goals and accompanying strategies are to be implemented by DOE sites through the integration of Pollution Prevention into each site's Environmental Management System (EMS). This document presents a P2 and Sustainability Program and corresponding plan pursuant to DOE Order 450.1 and DOE O 435.1, Radioactive Waste Management. This plan is also required by the state of Idaho, pursuant to the Resource Conservation and Recovery Act (RCRA) partial permit. The objective of this document is to describe the Idaho National Laboratory (INL) Site P2 and Sustainability Program. The purpose of the program is to decrease the environmental footprint of the INL Site while providing enhanced support of its mission. The success of the program is dependent on financial and management support. The signatures on the previous page indicate INL, ICP, and AMWTP Contractor management support and dedication to the program. P2 requirements have been integrated into working procedures to ensure an effective EMS as part of an Integrated Safety Management System (ISMS). This plan focuses on programmatic functions which include environmentally preferable procurement, sustainable design, P2 and Sustainability awareness, waste generation and reduction, source reduction and recycling, energy management, and pollution prevention opportunity assessments. The INL Site P2 and Sustainability Program is administratively

  20. USDA National Nutrient Database for Standard Reference, Release 25

    USDA-ARS?s Scientific Manuscript database

    The USDA National Nutrient Database for Standard Reference, Release 25(SR25)contains data for over 8,100 food items for up to 146 food components. It replaces the previous release, SR24, issued in September 2011. Data in SR25 supersede values in the printed handbooks and previous electronic releas...

  1. USDA National Nutrient Database for Standard Reference, release 28

    USDA-ARS?s Scientific Manuscript database

    The USDA National Nutrient Database for Standard Reference, Release 28 contains data for nearly 8,800 food items for up to 150 food components. SR28 replaces the previous release, SR27, originally issued in August 2014. Data in SR28 supersede values in the printed handbooks and previous electronic...

  2. Pacific Northwest National Laboratory Institutional Plan FY 2004-2008

    SciTech Connect

    Quadrel, Marilyn J.

    2004-04-15

    This Institutional Plan for FY 2004-2008 is the principal annual planning document submitted to the Department of Energy's Office of Science by Pacific Northwest National Laboratory in Richland, Washington. This plan describes the Laboratory's mission, roles, and technical capabilities in support of Department of Energy priorities, missions, and plans. It also describes the Laboratory strategic plan, key planning assumptions, major research initiatives, and program strategy for fundamental science, energy resources, environmental quality, and national security.

  3. Brookhaven National Laboratory Institutional Plan FY2001--FY2005

    SciTech Connect

    Davis, S.

    2000-10-01

    Brookhaven National Laboratory is a multidisciplinary laboratory in the Department of Energy National Laboratory system and plays a lead role in the DOE Science and Technology mission. The Laboratory also contributes to the DOE missions in Energy Resources, Environmental Quality, and National Security. Brookhaven strives for excellence in its science research and in facility operations and manages its activities with particular sensitivity to environmental and community issues. The Laboratory's programs are aligned continuously with the goals and objectives of the DOE through an Integrated Planning Process. This Institutional Plan summarizes the portfolio of research and capabilities that will assure success in the Laboratory's mission in the future. It also sets forth BNL strategies for our programs and for management of the Laboratory. The Department of Energy national laboratory system provides extensive capabilities in both world class research expertise and unique facilities that cannot exist without federal support. Through these national resources, which are available to researchers from industry, universities, other government agencies and other nations, the Department advances the energy, environmental, economic and national security well being of the US, provides for the international advancement of science, and educates future scientists and engineers.

  4. Cold War Context Statement: Sandia National Laboratories, California Site

    SciTech Connect

    ULLRICH, REBECCA A.

    2003-01-01

    This document was prepared to support the Department of Energy's compliance with Sections 106 and 110 of the National Historic Preservation Act. It provides an overview of the historic context in which Sandia National Laboratories/California was created and developed. Establishing such a context allows for a reasonable and reasoned historical assessment of Sandia National Laboratories/California properties. The Cold War arms race provides the primary historical context for the SNL/CA built environment.

  5. Pacific Northwest National Laboratory institutional plan: FY 1996--2001

    SciTech Connect

    1996-01-01

    This report contains the operation and direction plan for the Pacific Northwest National Laboratory of the US Department of Energy. The topics of the plan include the laboratory mission and core competencies, the laboratory strategic plan; the laboratory initiatives in molecular sciences, microbial biotechnology, global environmental change, complex modeling of physical systems, advanced processing technology, energy technology development, and medical technologies and systems; core business areas, critical success factors, and resource projections.

  6. [Assessment of Hepatitis C Virus Diversity in Addition to the Frequency of Genotypes in Samples Analyzed Between 2009 and 2014 at the Reference Laboratory of National Health Institute Dr. Ricardo Jorge].

    PubMed

    Pádua, Elizabeth; Avó, Ana Patricia; Almeida, Catarina; Água Doce, Ivone; Cortes Martins, Helena

    2015-01-01

    The identification of genotypes was essential for the prognosis and treatment of hepatitis C virus chronic patients in recent years. The aims of the study were to know the frequency of genotypes diagnosed in the last six years at the laboratory, and reveal the contribution of an in-house assay for molecular characterization of viruses. The genotyping of hepatitis C virus by LiPA was performed in 923 samples, mostly from male individuals. The subtyping of hepatitis C virus by an in-house assay to target regions in the Core/E1 and/or NS5B was performed in 112 samples. We observed a high prevalence of genotype 1 (56.6%), with a frequency of subtype 1a four times higher compared to 1b. All cases of genotype 3 (27.5%) were subtype 3a. For the cases of genotype 4 (12.9%), it were identified subtypes 4a (65.5%), 4d (31%), 4b (1.7%) and 4c (1.7%). Recombinants intragenotype 2, the RF1_2k/1b, and mixed infections, were also identified. The most prevalent subtypes (1a and 3a) obtained are usually described in injecting drug users. Although most of the samples analysed match to inmates (78.4%), we cannot exclude any possible risk behaviors associated with illicit drug use. The high prevalence of subtype 1a, the frequency and diversity of genotype 4, and the identification of recombined virus suggest modification of the molecular pattern of hepatitis C virus infection described in the past. The in-house assay proved to be useful for the correct classification of hepatitis C virus and improving knowledge about the diversity of virus circulating in the country.

  7. References from Brazilian medical journals in national publications.

    PubMed

    Teixeira, Renan Kleber Costa; Botelho, Nara Macedo; Petroianu, Andy

    2013-01-01

    To assess whether there is a preference for international journal citation to the detriment of national ones in ten Brazilian medical journals, in two different periods. All references in the articles published in Arquivos Brasileiros de Oftalmologia, Revista Brasileira de Cirurgia Cardiovascular, Revista da Associação Médica Brasileira, São Paulo Medical Journal, Arquivos Brasileiros de Endocrinologia e Metabologia, Clinics, Jornal Brasileiro de Pneumologia, Revista da Sociedade Brasileira de Medicina Tropical, Revista Brasileira de Psiquiatria e Acta Ortopédica Brasileira in the years 2011 and 2007 were analyzed, assessing the number of articles published in national and international journals. A total of 36,125 references from 1,462 articles published in the 10 aforementioned journals were analyzed. Of the total number, 4.242 (11.74%) were from Brazilian journals. There was no significant difference between the two analyzed periods. A total of 453 (30,98%) of the articles studied non-cited brazilian papers,and 81 (5.54%) articles had more Brazilian than international references. Of total references analyzed, 11.74% were related to articles published in Brazilian journals. This number, when compared to the percentage of Brazilian articles published in the medical area, demonstrates a good number of citations of national articles. Copyright © 2012 Elsevier Editora Ltda. All rights reserved.

  8. An improved auto-generation system to obtain reference intervals for laboratory medicine.

    PubMed

    Kim, Hyung Hoi; Hong, Hae Sook; Kim, Shine Young; Tran, Tung; Lee, Ji Min; Kim, Hwa Sun; Cho, Hune

    2010-03-01

    Reference values are highly required parameters for all tests in the clinical laboratory, and the supplementary provision of reliable reference intervals is an important task for both clinical laboratories and diagnostic test manufacturers. Despite the progress that has been made in the conceptual aspects of reference intervals, in practice their use is still not completely satisfactory. Most of the laboratories have used various methods to calculate statistic-based reference intervals, and they have mainly focused on extracted data, yet its use is considerably limited. We had to deal with the inconvenience of using a number of programs (SPSS or SAS, MS Excel) in order to calculate the results of reference intervals. In order to obtain standardized reference intervals, we developed an integrated program that can calculate, by a nonparametric method, reference intervals with using the Clinical and Laboratory Standards Institute (CLSI) processes as its guideline. We also developed a grouping interface that enables users to customize classification of each group (age, gender, blood group, race, etc) when calculating reference intervals. To verify the developed program, we compared the reference intervals of the current data on 281 persons for 8 total areas, and the reference intervals were was already calculated beforehand with by using this new program. As a result, both results perfectly matched. This integrated program will be convenience for calculating reasonable values through continual datainspection at an inspection lab for calculating reference intervals. The newly developed program will improve the consistency and reliability of the statistics on reference intervals.

  9. U.S. Geological Survey Standard Reference Sample Project: Performance Evaluation of Analytical Laboratories

    USGS Publications Warehouse

    Long, H. Keith; Daddow, Richard L.; Farrar, Jerry W.

    1998-01-01

    Since 1962, the U.S. Geological Survey (USGS) has operated the Standard Reference Sample Project to evaluate the performance of USGS, cooperator, and contractor analytical laboratories that analyze chemical constituents of environmental samples. The laboratories are evaluated by using performance evaluation samples, called Standard Reference Samples (SRSs). SRSs are submitted to laboratories semi-annually for round-robin laboratory performance comparison purposes. Currently, approximately 100 laboratories are evaluated for their analytical performance on six SRSs for inorganic and nutrient constituents. As part of the SRS Project, a surplus of homogeneous, stable SRSs is maintained for purchase by USGS offices and participating laboratories for use in continuing quality-assurance and quality-control activities. Statistical evaluation of the laboratories results provides information to compare the analytical performance of the laboratories and to determine possible analytical deficiences and problems. SRS results also provide information on the bias and variability of different analytical methods used in the SRS analyses.

  10. Los Alamos National Laboratory Perchlorate Issues.

    SciTech Connect

    Hjeresen, Denny; Rae, Steve; Beers, Bob; Saladen, Mike; Barr, Alice; Pope, Alicia; Dziewinski, Lacek; Scott, Jim; Holcomb, Robert; Hollis, Diana; Leslie Dale,; Williams, Laurie; Strietelmeier, Betty; Carlson, Bryan; Alexander, Rick; Worland, Pete; Hanson, Steve; Stine, Jim; Hiskey, Mike; Archuleta, Jose; Kinkead, Scott; Sherrard, Ann; Longmire, Pat; Witkowski, Marc; Gard, Marvin

    2003-08-04

    This document reviews the chemical structure of the perchlorate anion and the uses of perchlorates, related health issues, applicable drinking water regulations, water supply system monitoring, current laboratory perchlorate use, management of perchlorate compound risks, potential perchlorate sites and sources, the search for a lower perchlorate detection limit, and treatment of perchlorate contamination.

  11. Use of a United States-based laboratory as a hematopathology reference center for a developing country: logistics and results.

    PubMed

    Deetz, C O; Scott, M G; Ladenson, J H; Seyoum, M; Hassan, A; Kreisel, F H; Nguyen, T T; Frater, J L

    2013-02-01

    With proper logistical support and sponsorship, a laboratory in an industrialized nation might be able to act as a reference laboratory for clinicians based in a developing country. We built on previous experience in the clinical laboratory to see whether a specialized histopathology service (hematopathology) could be provided to a developing country without the expertise or experience to do it in country. Over an 13-year period, 582 cases from 579 individuals were analyzed. Principal pathologic findings included acute leukemia in 84 cases (14%), dyspoiesis in one or more of the hematopoietic lineages in 65 cases (11%, including three cases with high-grade myelodysplasia), 23 cases (4%) with findings suspicious for a chronic myeloproliferative disorder, 35 cases (6%) with findings suspicious for a lymphoproliferative disorder, and infectious organisms (presumably Leishmania in most instances) in 9 (1%) of cases. Specimens from 45 cases (8%) were unsatisfactory owing to extreme hemodilution and/or specimen degeneration. With proper support, a medical laboratory in an industrialized nation may serve as a reference facility for a developing nation. The use of existing infrastructure may be remarkably effective to achieve optimal turnaround time. Although the lack of ancillary studies and follow-up biopsies limit the ability to achieve a definitive diagnosis in many cases, this must be viewed in the context of the limited ability to diagnose or manage hematopoietic neoplasia in developing nations. © 2012 Blackwell Publishing Ltd.

  12. Recommendation for the review of biological reference intervals in medical laboratories.

    PubMed

    Henny, Joseph; Vassault, Anne; Boursier, Guilaine; Vukasovic, Ines; Mesko Brguljan, Pika; Lohmander, Maria; Ghita, Irina; Andreu, Francisco A Bernabeu; Kroupis, Christos; Sprongl, Ludek; Thelen, Marc H M; Vanstapel, Florent J L A; Vodnik, Tatjana; Huisman, Willem; Vaubourdolle, Michel

    2016-12-01

    This document is based on the original recommendation of the Expert Panel on the Theory of Reference Values of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC), updated guidelines were recently published under the auspices of the IFCC and the Clinical and Laboratory Standards Institute (CLSI). This document summarizes proposals for recommendations on: (i) The terminology, which is often confusing, noticeably concerning the terms of reference limits and decision limits. (ii) The method for the determination of reference limits according to the original procedure and the conditions, which should be used. (iii) A simple procedure allowing the medical laboratories to fulfill the requirements of the regulation and standards. The updated document proposes to verify that published reference limits are applicable to the laboratory involved. Finally, the strengths and limits of the revised recommendations (especially the selection of the reference population, the maintenance of the analytical quality, the choice of the statistical method used…) will be briefly discussed.

  13. The Spanish National Reference Database for Ionizing Radiations (BANDRRI)

    PubMed

    Los Arcos JM; Bailador; Gonzalez; Gonzalez; Gorostiza; Ortiz; Sanchez; Shaw; Williart

    2000-03-01

    The Spanish National Reference Database for Ionizing Radiations (BANDRRI) is being implemented by a reasearch team in the frame of a joint project between CIEMAT (Unidad de Metrologia de Radiaciones Ionizantes and Direccion de Informatica) and the Universidad Nacional de Educacion a Distancia (UNED, Departamento de Mecanica y Departamento de Fisica de Materiales). This paper presents the main objectives of BANDRRI, its dynamic and relational data base structure, interactive Web accessibility and its main radionuclide-related contents at this moment.

  14. CONTROL TESTING OF THE UK NATIONAL NUCLEAR LABORATORY'S RADBALL TECHNOLOGY AT SAVANNAH RIVER NATIONAL LABORATORY

    SciTech Connect

    Farfan, E.

    2009-11-23

    The UK National Nuclear Laboratory (NNL) has developed a remote, non-electrical, radiation-mapping device known as RadBall (patent pending), which offers a means to locate and quantify radiation hazards and sources within contaminated areas of the nuclear industry. To date, the RadBall has been deployed in a number of technology trials in nuclear waste reprocessing plants at Sellafield in the UK. The trials have demonstrated the successful ability of the RadBall technology to be deployed and retrieved from active areas. The positive results from these initial deployment trials and the anticipated future potential of RadBall have led to the NNL partnering with the Savannah River National Laboratory (SRNL) to further underpin and strengthen the technical performance of the technology. RadBall consists of a colander-like outer shell that houses a radiation-sensitive polymer sphere. It has no power requirements and can be positioned in tight or hard-to reach places. The outer shell works to collimate radiation sources and those areas of the polymer sphere that are exposed react, becoming increasingly less transparent, in proportion to the absorbed dose. The polymer sphere is imaged in an optical-CT scanner which produces a high resolution 3D map of optical attenuation coefficients. Subsequent analysis of the optical attenuation maps provides information on the spatial distribution and strength of the sources in a given area forming a 3D characterization of the area of interest. This study completed at SRNL addresses key aspects of the testing of the RadBall technology. The first set of tests was performed at Savannah River Nuclear Solutions Health Physics Instrument Calibration Laboratory (HPICL) using various gamma-ray sources and an x-ray machine with known radiological characteristics. The objective of these preliminary tests was to identify the optimal dose and collimator thickness. The second set of tests involved a highly contaminated hot cell. The objective of

  15. B-cell subpopulations in children: National reference values

    PubMed Central

    Duchamp, Marie; Sterlin, Delphine; Diabate, Aminata; Uring-Lambert, Béatrice; Guérin-El Khourouj, Valérie; Le Mauff, Brigitte; Monnier, Delphine; Malcus, Christophe; Labalette, Myriam; Picard, Capucine

    2014-01-01

    Peripheral B-lymphocytes undergo a series of changes during the first few years of life. Encounters with foreign antigens lead to maturation and differentiation. Several primary antibody deficiencies (PADs) affecting B-cell development are associated with abnormalities in the composition and/or differentiation of B-cell compartments. The most recent international classifications of primary immunodeficiencies (PIDs) and common variable immunodeficiencies (CVID) have highlighted the importance of B-cell immunophenotyping and age-specific reference intervals for diagnostic purposes. We established national reference values for memory B-cell subpopulations, on the basis of CD27 and surface IgD expression in the peripheral blood of 242 healthy children. We report here the absolute counts and percentages of naive, switched and non-switched memory B-cells for seven age groups, from neonates to adults. We found that the naive B-cells percentage declined between the ages of 6 months and 8 years, after which it remained stable at about 70–80%. Memory B-cells are already present at birth and their numbers increase throughout childhood, stabilizing between the ages of 12 and 18 years. The definition of reference intervals for pediatric B-cell levels should facilitate the screening and diagnosis of various B-cell immunodeficiencies. This multicenter study, providing national reference values, should thus facilitate immunological diagnosis in children. PMID:25505547

  16. B-cell subpopulations in children: National reference values.

    PubMed

    Duchamp, Marie; Sterlin, Delphine; Diabate, Aminata; Uring-Lambert, Béatrice; Guérin-El Khourouj, Valérie; Le Mauff, Brigitte; Monnier, Delphine; Malcus, Christophe; Labalette, Myriam; Picard, Capucine

    2014-11-01

    Peripheral B-lymphocytes undergo a series of changes during the first few years of life. Encounters with foreign antigens lead to maturation and differentiation. Several primary antibody deficiencies (PADs) affecting B-cell development are associated with abnormalities in the composition and/or differentiation of B-cell compartments. The most recent international classifications of primary immunodeficiencies (PIDs) and common variable immunodeficiencies (CVID) have highlighted the importance of B-cell immunophenotyping and age-specific reference intervals for diagnostic purposes. We established national reference values for memory B-cell subpopulations, on the basis of CD27 and surface IgD expression in the peripheral blood of 242 healthy children. We report here the absolute counts and percentages of naive, switched and non-switched memory B-cells for seven age groups, from neonates to adults. We found that the naive B-cells percentage declined between the ages of 6 months and 8 years, after which it remained stable at about 70-80%. Memory B-cells are already present at birth and their numbers increase throughout childhood, stabilizing between the ages of 12 and 18 years. The definition of reference intervals for pediatric B-cell levels should facilitate the screening and diagnosis of various B-cell immunodeficiencies. This multicenter study, providing national reference values, should thus facilitate immunological diagnosis in children.

  17. DEMONSTRATION BULLETIN: IN SITU ELECTROKINETIC EXTRACTION SYSTEM - SANDIA NATIONAL LABORATORIES

    EPA Science Inventory

    Sandia National Laboratories (SNL) has developed an in situ soil remediation system that uses electrokinetic principles to remediate hexavalent chromium-contaminated unsaturated or partially saturated soils. The technology involves the in situ application of direct current to the...

  18. 1992 Environmental monitoring report, Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Culp, T.; Cox, W.; Hwang, H.; Irwin, M.; Jones, A.; Matz, B.; Molley, K.; Rhodes, W.; Stermer, D.; Wolff, T.

    1993-09-01

    This 1992 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. summaries of significant environmental compliance programs in progress, such as National Environmental Policy Act documentation, environmental permits, envirorunental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque, New Mexico, are included. The maximum offsite dose impact was calculated to be 0.0034 millirem. The total population within a 50-mile radius of Sandia National Laboratories/New Mexico received an estimated collective dose of 0.019 person-rem during 1992 from the laboratories` operations. As in the previous year, the 1992 operations at Sandia National Laboratories/New Mexico had no discernible impact on the general public or on the environment.

  19. 60 years of great science [Oak Ridge National Laboratory

    SciTech Connect

    2003-01-01

    This issue highlights Oak Ridge National Laboratory's contributions in more than 30 areas of research and related activities during the past 60 years and provides glimpses of current activities that are carrying on this heritage.

  20. NATIONAL ENVIRONMENTAL LABORATORY ACCREDITATION CONFERENCE (NELAC): CONSTITUTION, BYLAWS, AND STANDARDS

    EPA Science Inventory

    The principles and operating procedures for the National Environmental Laboratory Accreditation Conference (NELAC) are contained in the NELAC Constitution and Bylaws. The major portion of this document (standards) contains detailed requirements for accrediting environmental labo...

  1. 1993 Site environmental report Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Culp, T.A.; Cheng, C.F.; Cox, W.; Durand, N.; Irwin, M.; Jones, A.; Lauffer, F.; Lincoln, M.; McClellan, Y.; Molley, K.

    1994-11-01

    This 1993 report contains monitoring data from routine radiological and nonradiological environmental surveillance activities. Summaries of significant environmental compliance programs in progress, such as National Environmental Policy Act documentation, environmental permits, environmental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque, New Mexico, are included. The maximum offsite dose impact was calculated to be 0.0016 millirem. The total population within a 50-mile (80 kilometer) radius of Sandia National Laboratories/New Mexico received an estimated collective dose of 0.027 person-rem during 1993 from the laboratories operations, As in the previous year, the 1993 operations at Sandia National Laboratories/New Mexico had no discernible impact on the general public or on the environment. This report is prepared for the U.S. Department of Energy in compliance with DOE Order 5400.1.

  2. DEMONSTRATION BULLETIN: IN SITU ELECTROKINETIC EXTRACTION SYSTEM - SANDIA NATIONAL LABORATORIES

    EPA Science Inventory

    Sandia National Laboratories (SNL) has developed an in situ soil remediation system that uses electrokinetic principles to remediate hexavalent chromium-contaminated unsaturated or partially saturated soils. The technology involves the in situ application of direct current to the...

  3. High-temperature superconductor applications development at Argonne National Laboratory

    SciTech Connect

    Hull, J.R.; Poeppel, R.B.

    1992-02-09

    Developments at Argonne National Laboratory of near and intermediate term applications using high-temperature superconductors are discussed. Near-term applications of liquid-nitrogen depth sensors, current leads, and magnetic bearings are discussed in detail.

  4. NATIONAL ENVIRONMENTAL LABORATORY ACCREDITATION CONFERENCE (NELAC): CONSTITUTION, BYLAWS, AND STANDARDS

    EPA Science Inventory

    The principles and operating procedures for the National Environmental Laboratory Accreditation Conference (NELAC) are contained in the NELAC Constitution and Bylaws. The major portion of this document (standards) contains detailed requirements for accrediting environmental labo...

  5. Criticality emergency planning at Oak Ridge National Laboratory

    SciTech Connect

    Green, J.H.; Cain, G.C.

    1983-01-01

    A plan to protect personnel and control the spread of contamination in the event of a radiation accident at Oak Ridge National Laboratory (ORNL) is outlined. Procedures and personnel are presented. (ACK)

  6. High-temperature superconductor applications development at Argonne National Laboratory

    SciTech Connect

    Hull, J.R.; Poeppel, R.B.

    1992-02-09

    Developments at Argonne National Laboratory of near and intermediate term applications using high-temperature superconductors are discussed. Near-term applications of liquid-nitrogen depth sensors, current leads, and magnetic bearings are discussed in detail.

  7. Former Fermilab boss to lead Lawrence Berkeley National Laboratory

    NASA Astrophysics Data System (ADS)

    Gwynne, Peter

    2016-03-01

    Particle physicist Michael Witherell - current vice-chancellor for research at the University of California, Santa Barbara (UCSB) - has been appointed the next director of the Lawrence Berkeley National Laboratory (LBL).

  8. High-temperature superconductor applications development at Argonne National Laboratory

    NASA Astrophysics Data System (ADS)

    Hull, J. R.; Poeppel, R. B.

    1992-02-01

    Developments at Argonne National Laboratory of near and intermediate term applications using high-temperature superconductors are discussed. Near-term applications of liquid-nitrogen depth sensors, current leads, and magnetic bearings are discussed in detail.

  9. Transport Energy Impact Analysis; NREL (National Renewable Energy Laboratory)

    SciTech Connect

    Gonder, J.

    2015-05-13

    Presented at the Sustainable Transportation Energy Pathways Spring 2015 Symposium on May 13, 2015, this presentation by Jeff Gonder of the National Renewable Energy Laboratory (NREL) provides information about NREL's transportation energy impact analysis of connected and automated vehicles.

  10. Argonne National Laboratory Wins EPA Federal Green Challenge Award

    EPA Pesticide Factsheets

    CHICAGO -- The U.S. Environmental Protection Agency today announced that the Argonne National Laboratory has won Federal Green Challenge awards for waste reduction, transportation and electronics. The Challenge encourages federal agencies throughout the na

  11. New Datums for the Nation: Modernizing the United States National Spatial Reference System

    NASA Astrophysics Data System (ADS)

    Stone, W. A.; Caccamise, D. J., II

    2016-12-01

    The mission of the National Oceanic and Atmospheric Administration's National Geodetic Survey (NGS) is "to define, maintain and provide access to the National Spatial Reference System (NSRS) to meet our nation's economic, social, and environmental needs." NSRS is the nation's system of latitude, longitude, height (geometric and orthometric), and related geophysical and geodetic models and tools, which provides a consistent spatial reference framework for the broad spectrum of geoscientific applications and the majority of civilian positioning requirements. Technological developments - notably Global Navigation Satellite Systems (GNSS) - and user accuracy requirements necessitate that NGS modernize the NSRS. Preparations are underway by NGS for a comprehensive NSRS makeover, to be completed in 2022 and delivered through a new generation of horizontal and vertical datums (reference frames), featuring unprecedented accuracy, repeatability, and efficiency of access. This evolution is outlined in the "National Geodetic Survey Ten-Year Strategic Plan, 2013-2023." This poster will outline the motivations for this effort and the planned evolution of NSRS. New geometric and geopotential (elevation) frameworks are fundamental to the delivery of the future datum paradigms. The new geometric reference frame, realized through GPS/GNSS Continuously Operating Reference Stations (CORS), will replace the backbone North American Datum of 1983 (NAD83) and will provide a modern spatial latticework for determination of latitude, longitude, and ellipsoid height. Complementing the new geometric reference frame will be a co-released geopotential reference frame, based on a national gravimetric geoid and replacing the North American Vertical Datum of 1988 (NAVD88). The gravimetric geoid - or definitional reference surface (zero elevation) - for the future geopotential reference frame will be built from airborne gravimetric data collected in the ongoing NGS project - Gravity for the

  12. National strategic challenges and the role of Lawrence Livermore National Laboratory

    SciTech Connect

    Al-Ayat, R.A.; Chrzanowski, P.L.; Werne, R.W.

    1995-01-01

    The end of the Cold War was a water-shed event in history--an event that calls for re-evaluation of the basic assumptions and priorities of US national security that have gone essentially unchallenged for nearly 50 years. Central to this re-evaluation are the changing needs for federal Science and Technology (S and T) investment to underpin national and economic security and the role of the Department of Energy (DOE) national laboratories in fulfilling those needs. The three nuclear weapons laboratories-Los Alamos National Laboratory (LANL), Lawrence Livermore National Laboratory (LLNL), and Sandia National Laboratory (SNL)-are major constituents of DOE`s national laboratory system. They helped win the Cold War, and will undoubtedly continue to support US security S and T requirements. This paper discusses of the role these three laboratories, and LLNL in particular, can play in supporting the nation`s S and T priorities. The paper also highlights some of the changes that are necessary for the laboratories to effectively support the national S and T and economic competitiveness agenda. These issues are important to DOE and laboratory managers responsible for the development of strategic direction and implementation plans.

  13. External Quality Assessment Scheme for reference laboratories - review of 8 years' experience.

    PubMed

    Kessler, Anja; Siekmann, Lothar; Weykamp, Cas; Geilenkeuser, Wolf Jochen; Dreazen, Orna; Middle, Jonathan; Schumann, Gerhard

    2013-05-01

    We describe an External Quality Assessment Scheme (EQAS) intended for reference (calibration) laboratories in laboratory medicine and supervised by the Scientific Division of the International Federation of Clinical Chemistry and Laboratory Medicine and the responsible Committee on Traceability in Laboratory Medicine. The official EQAS website, RELA (www.dgkl-rfb.de:81), is open to interested parties. Information on all requirements for participation and results of surveys are published annually. As an additional feature, the identity of every participant in relation to the respective results is disclosed. The results of various groups of measurands (metabolites and substrates, enzymes, electrolytes, glycated hemoglobins, proteins, hormones, thyroid hormones, therapeutic drugs) are discussed in detail. The RELA system supports reference measurement laboratories preparing for accreditation according to ISO 17025 and ISO 15195. Participation in a scheme such as RELA is one of the requirements for listing of the services of a calibration laboratory by the Joint Committee on Traceability in Laboratory Medicine.

  14. Industrial ecology at Lawrence Livermore National Laboratory summary statement

    SciTech Connect

    Gilmartin, T.J.

    1996-05-21

    This statement summarizes Lawrence Livermore National Laboratory`s committment to making important scientific, technological, and business contributions to global sustainability. The quest has many aspects, some socio-political or economic and some technological, and some in which the soft and hard sciences become indistinguishable, as in visionary national strategies, like Holland`s, and futuristic regional and city development plans, like those of Kagoshima and Chattanooga.

  15. A plea for intra-laboratory reference limits. Part 1. General considerations and concepts for determination.

    PubMed

    Haeckel, Rainer; Wosniok, Werner; Arzideh, Farhad

    2007-01-01

    Accurate results for quantitative procedures can be useless if the reference limits for the interpretation of laboratory results are unreliable. Recent concepts for quality management systems require that laboratories pay more attention to identification and verification of reference limits. Scientific recommendations often claim that each laboratory should determine intra-laboratory reference limits, which should be reviewed periodically. This recommendation is currently neglected by most laboratories; instead they use reference limits from external sources, despite various problems of transference. Prospective and retrospective methods either using or neglecting disease prevalences (polymodal or unimodal concepts, respectively) and applying different statistical approaches for determining reference limits have been described. The various procedures are reviewed with regard to their diagnostic sensitivity, specificity and (non-)efficiency. The present gold standard is the reference limit concept according to IFCC recommendations (a unimodal prospective approach). This concept, together with trueness-based standardization, is the most useful basis for harmonization of the decision-making process with laboratory results, despite complex problems of traceability and transference. This harmonization is at present only achieved for a limited number of analytes for which SI units and traceability can be technically realized. For the majority of measurands in laboratory medicine, much research is still required and results cannot be expected in the near future. For these measurands, a need remains for internal, efficient and simple identification of population-based reference limits. Therefore, newer retrospective concepts were developed that use large data sets from laboratory information systems to derive intra-laboratory reference limits. These approaches appear promising and should be further developed.

  16. 2020 Foresight Forging the Future of Lawrence Livermore National Laboratory

    SciTech Connect

    Chrzanowski, P.

    2000-01-01

    The Lawrence Livermore National Laboratory (LLNL) of 2020 will look much different from the LLNL of today and vastly different from how it looked twenty years ago. We, the members of the Long-Range Strategy Project, envision a Laboratory not defined by one program--nuclear weapons research--but by several core programs related to or synergistic with LLNL's national security mission. We expect the Laboratory to be fully engaged with sponsors and the local community and closely partnering with other research and development (R&D) organizations and academia. Unclassified work will be a vital part of the Laboratory of 2020 and will visibly demonstrate LLNL's international science and technology strengths. We firmly believe that there will be a critical and continuing role for the Laboratory. As a dynamic and versatile multipurpose laboratory with a national security focus, LLNL will be applying its capabilities in science and technology to meet the needs of the nation in the 21st century. With strategic investments in science, outstanding technical capabilities, and effective relationships, the Laboratory will, we believe, continue to play a key role in securing the nation's future.

  17. The quality of veterinary in-clinic and reference laboratory biochemical testing.

    PubMed

    Rishniw, Mark; Pion, Paul D; Maher, Tammy

    2012-03-01

    Although evaluation of biochemical analytes in blood is common in veterinary practice, studies assessing the global quality of veterinary in-clinic and reference laboratory testing have not been reported. The aim of this study was to assess the quality of biochemical testing in veterinary laboratories using results obtained from analyses of 3 levels of assayed quality control materials over 5 days. Quality was assessed by comparison of calculated total error with quality requirements, determination of sigma metrics, use of a quality goal index to determine factors contributing to poor performance, and agreement between in-clinic and reference laboratory mean results. The suitability of in-clinic and reference laboratory instruments for statistical quality control was determined using adaptations from the computerized program, EZRules3. Reference laboratories were able to achieve desirable quality requirements more frequently than in-clinic laboratories. Across all 3 materials, > 50% of in-clinic analyzers achieved a sigma metric ≥ 6.0 for measurement of 2 analytes, whereas > 50% of reference laboratory analyzers achieved a sigma metric ≥ 6.0 for measurement of 6 analytes. Expanded uncertainty of measurement and ± total allowable error resulted in the highest mean percentages of analytes demonstrating agreement between in-clinic and reference laboratories. Owing to marked variation in bias and coefficient of variation between analyzers of the same and different types, the percentages of analytes suitable for statistical quality control varied widely. These findings reflect the current state-of-the-art with regard to in-clinic and reference laboratory analyzer performance and provide a baseline for future evaluations of the quality of veterinary laboratory testing. © 2012 American Society for Veterinary Clinical Pathology.

  18. Partnering with Sandia National Laboratories through alliances or consortia

    SciTech Connect

    Winchell, B.M.

    1994-12-01

    To better facilitate working with industry, groups of industrial participants, and partners in alliances or consortia, Sandia National Laboratories presents information helpful to those outside groups as to the forms of arrangements that may be used to better facilitate partnering relationships between Sandia National Laboratories and consortia or alliances of outside parties. It is expected that these alliances and consortia will include both large and small for-profit industrial concerns, as well as not-for-profit entities such as universities, institutes, other research facilities, and other nonprofit institutions or consortia containing institutions. The intent of this report is to provide such outside groups with information that will facilitate rapid interactions with Sandia National Laboratories through some of these forms of business which will be discussed in this report. These are not the only approaches to facilitating business interactions with Sandia National Laboratories and it is not intended that this report be legal advice or required approaches to doing business with Sandia National Laboratories. The intent of this report is merely to suggest ways in which Sandia National Laboratories can work with outside parties in the most expeditious manner.

  19. Partnering with Sandia National Laboratories through alliances or consortia

    SciTech Connect

    Winchell, B.M.

    1994-04-01

    To better facilitate working with industry, groups of industrial participants, and partners in alliances or consortia, Sandia National laboratories presents information helpful to those outside groups as to the forms of arrangements that may be used to better facilitate partnering relationships between Sandia National Laboratories and consortia or alliances of outside parties. It is expected that these alliances and consortia will include both large and small for-profit industrial concerns, as well as not-for-profit entities such as universities, institutes, other research facilities, and other nonprofit institutions or consortia containing institutions. The intent of this report is to provide such outside groups with information that will facilitate rapid interactions with Sandia National Laboratories through some of these forms of business which will be discussed in this report. These are not the only approaches to facilitating business interactions with Sandia National Laboratories and it is not intended that this report be legal advice or required approaches to doing business with Sandia National Laboratories. The intent of this report is merely to suggest ways in which Sandia National Laboratories can work with outside parties in the most expeditious manner.

  20. [Molecular diagnosis of HFE mutations in routine laboratories. Results of a survey from reference laboratories in France].

    PubMed

    Jouanolle, Anne-Marie; Gérolami, Victoria; Ged, Cécile; Grandchamp, Bernard; Le Gac, Gérald; Pissard, Serge; Rochette, Jacques; Aguilar-Martinez, Patricia

    2012-01-01

    HFE-related hemochromatosis (HFE hemochromatosis) or type 1 hemochromatosis is an autosomal recessive disease characterized by progressive iron overload usually expressed in adulthood. The HFE gene, located on the short arm of chromosome 6 (6p21.3), encodes a protein that plays a crucial role in iron metabolism by modulating hepcidin synthesis in the liver. Homozygosity for the p.Cys282Tyr mutation accounts for nearly 80% of cases of hemochromatosis in France. Genetic testing is the key investigation to confirm the diagnosis of HFE hemochromatosis. A survey on routine practices was carried out among the eight reference laboratories of the French national network on genetic iron disorders. The main findings from this survey are as follows: 1) the p.Cys282Tyr mutation must be searched for as an initial step to establish the diagnosis of HFE hemochromatosis. This is in agreement with the recommendations of the French Health Authority (HAS) published in 2005. In these recommendations, homozygosity for the p.Cys282Tyr mutation with at least elevated transferrin saturation, is considered the only genotype that confirms of the diagnosis of HFE hemochromatosis; 2) in combination with the p.Cys282Tyr mutation (compound heterozygous genotypes), the p.Ser65Cys and the p.His63Asp variants may contribute to the occurrence of mild iron overload; 3) family screening is mandatory following the detection of homozygous individuals for the p.Cys282Tyr mutation.

  1. Oak Ridge National Laboratory site data for safety-analysis report

    SciTech Connect

    Fitzpatrick, F.C.

    1982-12-01

    The Oak Ridge National Laboratory site data contained herein were compiled in support of the United States Department of Energy (USDOE) Oak Ridge Operations Office Order OR 5481.1. That order sets forth assignment of responsibilities for safety analysis and review responsibilities and provides guidance relative to the content and format of safety analysis reports. The information presented in this document is intended for use by reference in individual safety analysis reports where applicable to support accident analyses or the establishment of design bases of significance to safety, and it is applicable only to Oak Ridge National Laboratory facilities in Bethel and Melton Valleys. This information includes broad descriptions of the site characteristics, radioactive waste handling and monitoring practices, and the organization and operating policies at Oak Ridge National Laboratory. The historical background of the Laboratory is discussed briefly and the overall physical situation of the facilities is described in the following paragraphs.

  2. MODS accreditation process for regional reference laboratories in Peru: validation by GenoType® MTBDRplus.

    PubMed

    Coronel, J; Roper, M; Mitchell, S; Castillo, E; Gamarra, N; Drobniewski, F; Luna, G; Mendoza, A; Moore, D A J

    2010-11-01

    Although considerable effort has been put into the development and evaluation of new diagnostics for tuberculosis (TB) and multidrug-resistant TB (MDR-TB), little attention has thus far been paid to the technical aspects of initiating quality-assured routine service use. For implementation of the microscopic-observation drug susceptibility (MODS) methodology in the Peruvian reference laboratory network, a laboratory accreditation process was devised; MODS results from an expert reference laboratory (Universidad Peruana Cayetano Heredia [UPCH]) were used as the standard against which implementing laboratory MODS results were judged to ensure that, prior to use for patient care, implementing laboratories achieved the same high performance with MODS as previously demonstrated in the research laboratory. To evaluate the validity of MODS-based accreditation and the concordance of MODS drug susceptibility testing (DST) with molecular testing. Head-to-head comparison of MODS DST results from implementing Peruvian regional reference laboratories and the accrediting expert MODS laboratory (UPCH) with GenoType® MTBDRplus DST. The concordance of phenotypic MODS rifampicin (RMP) DST with GenoType MTBDRplus was respectively 97.4%, 97.9% and 97.1% for the two implementing regional laboratories and UPCH, and respectively 94.7%, 95.7% and 94.6% for isoniazid (INH) DST. High and consistent levels of MODS/MTBDRplus concordance for INH and RMP DST confirm the validity of the use of rapid methods as reference standards for accreditation.

  3. MODS accreditation process for regional reference laboratories in Peru: validation by GenoType® MTBDRplus

    PubMed Central

    Coronel, J.; Roper, M.; Mitchell, S.; Castillo, E.; Gamarra, N.; Drobniewski, F.; Luna, G.; Mendoza, A.; Moore, D. A. J.

    2011-01-01

    SUMMARY SETTING Although considerable effort has been put into the development and evaluation of new diagnostics for tuberculosis (TB) and multidrug-resistant TB (MDR-TB), little attention has thus far been paid to the technical aspects of initiating quality-assured routine service use. For implementation of the microscopic-observation drug susceptibility (MODS) methodology in the Peruvian reference laboratory network, a laboratory accreditation process was devised; MODS results from an expert reference laboratory (Universidad Peruana Cayetano Heredia [UPCH]) were used as the standard against which implementing laboratory MODS results were judged to ensure that, prior to use for patient care, implementing laboratories achieved the same high performance with MODS as previously demonstrated in the research laboratory. OBJECTIVE To evaluate the validity of MODS-based accreditation and the concordance of MODS drug susceptibility testing (DST) with molecular testing. DESIGN Head-to-head comparison of MODS DST results from implementing Peruvian regional reference laboratories and the accrediting expert MODS laboratory (UPCH) with GenoType® MTBDRplus DST. RESULTS The concordance of phenotypic MODS rifampicin (RMP) DST with GenoType MTBDRplus was respectively 97.4%, 97.9% and 97.1% for the two implementing regional laboratories and UPCH, and respectively 94.7%, 95.7% and 94.6% for isoniazid (INH) DST. CONCLUSION High and consistent levels of MODS/MTBDRplus concordance for INH and RMP DST confirm the validity of the use of rapid methods as reference standards for accreditation. PMID:20937190

  4. Implementing a network for electronic surveillance reporting from public health reference laboratories: an international perspective.

    PubMed Central

    Bean, N. H.; Martin, S. M.

    2001-01-01

    Electronic data reporting from public health laboratories to a central site provides a mechanism for public health officials to rapidly identify problems and take action to prevent further spread of disease. However, implementation of reference laboratory systems is much more complex than simply adopting new technology, especially in international settings. We describe three major areas to be considered by international organizations for successful implementation of electronic reporting systems from public health reference laboratories: benefits of electronic reporting, planning for system implementation (e.g., support, resources, data analysis, country sovereignty), and components of system initiation (e.g., authority, disease definition, feedback, site selection, assessing readiness, problem resolution). Our experience with implementation of electronic public health laboratory data management and reporting systems in the United States and working with international organizations to initiate similar efforts demonstrates that successful reference laboratory reporting can be implemented if surveillance issues and components are planned. PMID:11747687

  5. Site Environmental Report for 2012 Sandia National Laboratories California

    SciTech Connect

    Larsen, Barbara L.

    2013-05-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, manages and operates the laboratory for the Department of Energy’s National Nuclear Security Administration (NNSA). The NNSA Sandia Field Office administers the contract and oversees contractor operations at the site. This Site Environmental Report for 2012 was prepared in accordance with DOE Order 231.1B, Environment, Safety and Health Reporting (DOE 2011d). The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2012. General site and environmental program information is also included.

  6. Site environmental report for 2011. Sandia National Laboratories, California

    SciTech Connect

    Larsen, Barbara L.

    2012-05-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractoroperated laboratory. Sandia Corporation, a wholly-owned subsidiary of Lockheed Martin Corporation, manages and operates the laboratory for the Department of Energy’s National Nuclear Security Administration (NNSA). The NNSA Sandia Site Office administers the contract and oversees contractor operations at the site. This Site Environmental Report for 2011 was prepared in accordance with DOE Order 231.1B, Environment, Safety and Health Reporting (DOE 2011d). The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2011. General site and environmental program information is also included.

  7. Precision and manufacturing at the Lawrence Livermore National Laboratory

    SciTech Connect

    Saito, T.T.; Wasley, R.J.; Stowers, I.F.; Donaldson, R.R.; Thompson, D.C.

    1993-11-01

    Precision Engineering is one of Lawrence Livermore National Laboratory`s core strengths. This paper discusses the past and present current technology transfer efforts of LLNL`s Precision Engineering program and the Livermore Center for Advanced Manufacturing and Productivity (LCAMP). More than a year ago the Precision Machining Commercialization project embodied several successful methods of transferring high technology from the National Laboratories to industry. Currently LCAMP has already demonstrated successful technology transfer and is involved in a broad spectrum of current programs. In addition this paper discusses other technologies ripe for future transition including the Large Optics Diamond Turning Machine.

  8. National Renewable Energy Laboratory: 35 Years of Innovation (Brochure)

    SciTech Connect

    Not Available

    2012-04-01

    This brochure is an overview of NREL's innovations over the last 35 years. It includes the lab's history and a description of the laboratory of the future. The National Renewable Energy Laboratory (NREL) is the U.S. Department of Energy's (DOE) primary national laboratory for renewable energy and energy efficiency. NREL's work focuses on advancing renewable energy and energy efficiency technologies from concept to the commercial marketplace through industry partnerships. The Alliance for Sustainable Energy, LLC, a partnership between Battelle and MRIGlobal, manages NREL for DOE's Office of Energy Efficiency and Renewable Energy.

  9. Site environmental report for 2004 Sandia National Laboratories, California.

    SciTech Connect

    Larsen, Barbara L. (Sandia National Laboratories, Livermore, CA)

    2005-06-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a Lockheed Martin Company, operates the laboratory for the Department of Energy's (DOE) National Nuclear Security Administration. The DOE Sandia Site Office oversees operations at the site, using Sandia Corporation as a management and operating contractor. This Site Environmental Report for 2004 was prepared in accordance with DOE Order 231.1A. The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2004. General site and environmental program information is also included.

  10. Site environmental report for 2008 Sandia National Laboratories, California.

    SciTech Connect

    Larsen, Barbara L.

    2009-04-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor operated laboratory. Sandia Corporation, a Lockheed Martin Company, operates the laboratory for the Department of Energy's National Nuclear Security Administration (NNSA). The NNSA Sandia Site Office oversees operations at the site, using Sandia Corporation as a management and operating contractor. This Site Environmental Report for 2008 was prepared in accordance with DOE Order 231.1A (DOE 2004a). The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2008. General site and environmental program information is also included.

  11. Site environmental report for 2005 Sandia National Laboratories, California.

    SciTech Connect

    Larsen, Barbara L.

    2006-06-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a Lockheed Martin Company, operates the laboratory for the Department of Energy's (DOE) National Nuclear Security Administration (NNSA). The DOE/NNSA Sandia Site Office (SSO) oversees operations at the site, using Sandia Corporation as a management and operating contractor. This Site Environmental Report for 2005 was prepared in accordance with DOE Order 231.1A. The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2005. General site and environmental program information is also included.

  12. Site environmental report for 2006 Sandia National Laboratories, California.

    SciTech Connect

    Larsen, Barbara L.

    2007-06-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a Lockheed Martin Company, operates the laboratory for the Department of Energy's National Nuclear Security Administration (NNSA). The NNSA Sandia Site Office oversees operations at the site, using Sandia Corporation as a management and operating contractor. This Site Environmental Report for 2006 was prepared in accordance with DOE Order 231.1A (DOE 2004a). The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2006. General site and environmental program information is also included.

  13. Site Environmental Report for 2007: Sandia National Laboratories, California

    SciTech Connect

    Larsen, Barbara L.

    2008-06-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a Lockheed Martin Company, operates the laboratory for the Department of Energy’s National Nuclear Security Administration (NNSA). The NNSA Sandia Site Office oversees operations at the site, using Sandia Corporation as a management and operating contractor. This Site Environmental Report for 2007 was prepared in accordance with DOE Order 231.1A (DOE 2004a). The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2007. General site and environmental program information is also included.

  14. Site environmental report for 2003 Sandia National Laboratories, California.

    SciTech Connect

    Larsen, Barbara L.

    2004-06-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a Lockheed Martin Company, operates the laboratory for the Department of Energy's (DOE) National Nuclear Security Administration. The DOE Sandia Site Office oversees operations at the site, using Sandia Corporation as a management and operating contractor. This Site Environmental Report for 2003 was prepared in accordance with DOE Order 231.1A. The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2003. General site and environmental program information is also included.

  15. Strengthening the Nation's Educational Systems through Programs at Argonne National Laboratory.

    ERIC Educational Resources Information Center

    Tolbert, Margaret E. M.

    1996-01-01

    Describes the educational programs at the Argonne National Laboratory that contribute to the development of a technically trained and diverse national workforce. Discusses precollege and college/university programs. (JRH)

  16. NAROM- a national Laboratory for space education

    NASA Astrophysics Data System (ADS)

    Hansen, Arne Hjalmar; Østbø, Morten

    2002-07-01

    Despite a considerable growth in space related industry and scientific research over the past few decades, space related education has largely been neglected in our country. NAROM - the National Centre for Space Related Education - was formed last year to organize space related educational activities, to promote recruitment, to promote appreciation for the benefits of space activities, and to stimulate interest for science in general. This year, nine students from Narvik Engineering College have participated in the Hotel Payload Project (HPP) at Andøya Rocket Range. They have thus played an active and essential role in an ongoing engineering project.

  17. Environmental Programs at Los Alamos National Laboratory

    SciTech Connect

    Jones, Patricia

    2012-07-11

    Summary of this project is: (1) Teamwork, partnering to meet goals - (a) Building on cleanup successes, (b) Solving legacy waste problems, (c) Protecting the area's environment; (2) Strong performance over the past three years - (a) Credibility from four successful Recovery Act Projects, (b) Met all Consent Order milestones, (c) Successful ramp-up of TRU program; (3) Partnership between the National Nuclear Security Administration's Los Alamos Site Office, DOE Carlsbad Field Office, New Mexico Environment Department, and contractor staff enables unprecedented cleanup progress; (4) Continued focus on protecting water resources; and (5) All consent order commitments delivered on time or ahead of schedule.

  18. Nuclear policy impacts at the national laboratories: maintaining the deterrence

    SciTech Connect

    Beck, James Bradley

    2010-08-24

    In this presentation, the author will discuss recent nuclear policy impacts, including the 2010 Nuclear Posture Review, and the impacts they have on maintaining the nuclear deterrent. Specifically, he will highlight some of the remaining questions and challenges that remain to the nation and to the national laboratories. (auth)

  19. 1995 Site environmental report Sandia National Laboratories, Albuquerque, New Mexico

    SciTech Connect

    Shyr, L.J.; Duncan, D.; Sanchez, R.

    1996-09-01

    This 1995 report contains data from routine radiological and non-radiological environmental monitoring activities. Summaries of significant environmental compliance programs in progress, such as National Environmental Policy Act documentation, environmental permits, environmental restoration and various waste management programs at Sandia National Laboratories in Albuquerque, New Mexico, are included.

  20. Solar energy at Sandia National Laboratories

    SciTech Connect

    1981-12-31

    Basic concepts for using the energy of the sun have been known for centuries. The challenge today, the goal of the Department of Energy`s National Solar Energy Program is to create the technology needed to establish solar energy as a practical, economical alternative to energy produced by depletable fuels--and to use that solar-produced energy in a wide variety of applications. To assist the DOE in this national effort, Sandia sponsors industrial and university research and development, manages a series of technical programs, operates solar experimental facilities, and carries out its own scientific and engineering research. This booklet describes their projects, their technical objectives, and explains how their experimental facilities are used to find the answers we`re seeking. Prospective participants from companies involved in solar-energy development or applications should find it especially useful since it outlines broad areas of opportunity. Projects include: central receiver technology; line-focus thermal technology; photovoltaic systems technology; wind turbine development; energy storage technology; and applied research in improved polycrystalline materials for solar cells and photoelectrolysis of water.

  1. Brookhaven National Laboratory site environmental report for calendar year 1995

    SciTech Connect

    Naidu, J.R.; Paquette, D.E.; Schroeder, G.L.

    1996-12-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and summarizes information about environmental compliance for 1995. To evaluate the effect of Brookhaven National Laboratory`s operations on the local environment, measurements of direct radiation, and of a variety of radionuclides and chemical compounds in the ambient air, soil, sewage effluent, surface water, groundwater, fauna, and vegetation were made at the Brookhaven National Laboratory site and at adjacent sites. The report also evaluates the Laboratory`s compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions and effluents to the environment. Areas of known contamination are subject to Remedial Investigation/Feasibility Studies under the Inter Agency Agreement established by the Department of Energy, Environmental Protection Agency and the New York Department of Environmental Conservation. Except for identified areas of soil and groundwater contamination, the environmental monitoring data has continued to demonstrate that compliance was achieved with the applicable environmental laws and regulations governing emission and discharge of materials to the environment. Also, the data show that the environmental impacts at Brookhaven National Laboratory are minimal and pose no threat to the public nor to the environment. This report meets the requirements of Department of Energy Orders 5484.1, Environmental Protection, Safety, and Health Protection Information reporting requirements and 5400.1, General Environmental Protection Programs.

  2. Standardization in laboratory medicine: Adoption of common reference intervals to the Croatian population

    PubMed Central

    Flegar-Meštrić, Zlata; Perkov, Sonja; Radeljak, Andrea

    2016-01-01

    Considering the fact that the results of laboratory tests provide useful information about the state of health of patients, determination of reference value is considered an intrinsic part in the development of laboratory medicine. There are still huge differences in the analytical methods used as well as in the associated reference intervals which could consequently significantly affect the proper assessment of patient health. In a constant effort to increase the quality of patients’ care, there are numerous international initiatives for standardization and/or harmonization of laboratory diagnostics in order to achieve maximum comparability of laboratory test results and improve patient safety. Through the standardization and harmonization processes of analytical methods the ability to create unique reference intervals is achieved. Such reference intervals could be applied globally in all laboratories using methods traceable to the same reference measuring system and analysing the biological samples from the populations with similar socio-demographic and ethnic characteristics. In this review we outlined the results of the harmonization processes in Croatia in the field of population based reference intervals for clinically relevant blood and serum constituents which are in accordance with ongoing activity for worldwide standardization and harmonization based on traceability in laboratory medicine. PMID:27019800

  3. An approach to establish the uncertainty budget of catalytic activity concentration measurements in a reference laboratory.

    PubMed

    Rami, Laura; Canalias, Francesca

    2015-04-01

    Reference laboratories providing reference services recognized by the Joint Committee for Traceability in Laboratory Medicine (JCTLM) must be accredited as calibration laboratories according to ISO 17025 and ISO 15195. These standards require laboratories to establish an uncertainty budget, in which the uncertainty contributions of the relevant uncertainty components are specified. We present a model to estimate the measurement uncertainty of creatine kinase catalytic activity concentration results obtained by IFCC primary reference measurement procedure. The measurement uncertainty has been estimated by following the next steps: 1) specification of the measurand; 2) identification of the most relevant uncertainty sources; 3) estimation of standard uncertainties by either type A or type B evaluation; 4) estimation of combined uncertainty while taking into account sensitivity coefficients, as well as existence of correlated uncertainty sources; and 5) estimation of expanded uncertainty with a defined coverage probability. The estimated expanded uncertainty was 2.2% (k=2). Uncertainty sources with a significant contribution to the measurement uncertainty were the following: pH adjustment (0.68%), absorbance accuracy (0.48%), wavelength adjustment (0.20%), reaction temperature (0.19%), volume fraction of sample (0.15%) and absorbance linearity (0.06%). The present model is an approach to establish the uncertainty budget of primary reference procedures for the measurement of the catalytic activity concentration of enzymes, and aims at being an example to be followed by other reference laboratories, as well as by laboratories that carry out primary reference measurement procedures.

  4. Reference materials and intercomparison samples available from the Environmental Monitoring Systems Laboratory - Las Vegas

    SciTech Connect

    Kantor, E.J.; Laska, P.R.

    1985-06-01

    Reference materials and intercomparison samples may be obtained by laboratories involved in the analysis of environmental samples containing radioactivity, pesticides, toxic inorganic species, or toxic organic species. These reference materials and intercomparison samples are available from the US Environmental Protection Agency's Quality Assurance Division located at the Environmental Monitoring Systems Laboratory in Las Vegas (EMSL-LV). These materials are useful for incorporation into a laboratory's quality control program for the evaluation of the precision and accuracy of analytical work. Media used for radiation reference materials are pitchblende, Monazite ore, uranium mill tailings, Mancos shale, fly ash, and water spiked with radionuclides. Radioactivity intercomparison samples consist of water, milk, air, urine, and a simulated diet slurry spiked with radionuclides. Media available for toxic organic reference materials are sludge, shale oil, and rag oil, and for intercomparison samples are soil and water. Characterized fly ash, foundry sludge, and river sediment serve as reference materials for toxic inorganics, while spiked soil and water serve as intercomparison samples. Finally, spiked adipose tissue, blood plasma, urine, and water comprise the pesticide intercomparison samples, and, after the disclosure of the true pesticide compositions and concentrations of these samples, the laboratory can use the samples as reference materials. The reference materials are generally available continuously, but the intercomparison samples are distributed on a scheduled basis and in some cases only to certain laboratories. 9 tables.

  5. A History of Building 828, Sandia National Laboratories

    SciTech Connect

    Ullrich, Rebecca

    1999-08-01

    This report documents the history of Building 828 in Sandia National Laboratories' Technical Area I. Building 828 was constructed in 1946 as a mechanical test laboratory for Los Alamos' Z-Division (later Sandia) as it moved to Sandia Base. The building has undergone significant remodeling over the years and has had a variety of occupants. The building was evaluated in compliance with the National Historic Preservation Act, but was not eligible for the National Register of Historic Places. Nevertheless, for many Labs employees, it was a symbol of Sandia's roots in World War II and the Manhattan Project.

  6. Pacific Northwest National Laboratory Institutional Plan FY 2001-2005

    SciTech Connect

    Fisher, Darrell R.; Pearson, Erik W.

    2000-12-29

    The Pacific Northwest National Laboratory Institutional Plan for FY 2001-2005 sets forth the laboratory's mission, roles, technical capabilities, and laboratory strategic plan. In the plan, major initiatives also are proposed and the transitioning initiatives are discussed. The Programmatic Strategy section details our strategic intent, roles, and research thrusts in each of the U.S. Department of Energy's mission areas. The Operations/Infrastructure Strategic Plan section includes information on the laboratory's human resources; environment, safety, and health management; safeguards and security; site and facilities management; information resources management; managaement procatices and standards; and communications and trust.

  7. Pacific Northwest National Laboratory Institutional Plan FY 2000-2004

    SciTech Connect

    Pearson, Erik W.

    2000-03-01

    The Pacific Northwest National Laboratory Institutional Plan for FY 2000-2004 sets forth the laboratory's mission, roles, technical capabilities, and laboratory strategic plan. In the plan, major initiatives also are proposed and the transitioning initiatives are discussed. The Programmatic Strategy section details our strategic intent, roles, and research thrusts in each of the U.S. Department of Energy's mission areas. The Operations/Infrastructure Strategic Plan section includes information on the laboratory's human resources; environment, safety, and health management; safeguards and security; site and facilities management; information resources management; management practices and standards; and communications and trust.

  8. Oak Ridge National Laboratory Review: Volume 24, No. 2, 1991

    SciTech Connect

    Krause, C.

    1991-01-01

    The Oak Ridge National Laboratory (ORNL) is a multiprogram, multipurpose laboratory that conducts research in the physical, chemical, and life sciences; in fusion, fission, and fossil energy; and in energy conservation and other energy-related technologies. This review outlines some current endeavors of the lab. A state of the laboratory presentation is given by director, Alvin Trivelpiece. Research of single crystals for welding is described. The Science Alliance, a partnership between ORNL and the University of Tennessee, is chronicled. And several incites into distinguished personnel at the laboratory are given. (GHH)

  9. Oak Ridge National Laboratory Review: Volume 24, No. 2, 1991

    SciTech Connect

    Krause, C.

    1991-12-31

    The Oak Ridge National Laboratory (ORNL) is a multiprogram, multipurpose laboratory that conducts research in the physical, chemical, and life sciences; in fusion, fission, and fossil energy; and in energy conservation and other energy-related technologies. This review outlines some current endeavors of the lab. A state of the laboratory presentation is given by director, Alvin Trivelpiece. Research of single crystals for welding is described. The Science Alliance, a partnership between ORNL and the University of Tennessee, is chronicled. And several incites into distinguished personnel at the laboratory are given. (GHH)

  10. Pathfinder radar development at Sandia National Laboratories

    NASA Astrophysics Data System (ADS)

    Castillo, Steven

    2016-05-01

    Since the invention of Synthetic Aperture Radar imaging in the 1950's, users or potential users have sought to exploit SAR imagery for a variety of applications including the earth sciences and defense. At Sandia Laboratories, SAR Research and Development and associated defense applications grew out of the nuclear weapons program in the 1980's and over the years has become a highly viable ISR sensor for a variety of tactical applications. Sandia SAR systems excel where real-­-time, high-­-resolution, all-­-weather, day or night surveillance is required for developing situational awareness. This presentation will discuss the various aspects of Sandia's airborne ISR capability with respect to issues related to current operational success as well as the future direction of the capability as Sandia seeks to improve the SAR capability it delivers into multiple mission scenarios. Issues discussed include fundamental radar capabilities, advanced exploitation techniques and human-­-computer interface (HMI) challenges that are part of the advances required to maintain Sandia's ability to continue to support ever changing and demanding mission challenges.

  11. Pacific Northwest National Laboratory institutional plan FY 1997--2002

    SciTech Connect

    1996-10-01

    Pacific Northwest National Laboratory`s core mission is to deliver environmental science and technology in the service of the nation and humanity. Through basic research fundamental knowledge is created of natural, engineered, and social systems that is the basis for both effective environmental technology and sound public policy. Legacy environmental problems are solved by delivering technologies that remedy existing environmental hazards, today`s environmental needs are addressed with technologies that prevent pollution and minimize waste, and the technical foundation is being laid for tomorrow`s inherently clean energy and industrial processes. Pacific Northwest National Laboratory also applies its capabilities to meet selected national security, energy, and human health needs; strengthen the US economy; and support the education of future scientists and engineers. Brief summaries are given of the various tasks being carried out under these broad categories.

  12. Evaluation of Radiometers in Full-Time Use at the National Renewable Energy Laboratory Solar Radiation Research Laboratory

    SciTech Connect

    Wilcox, S. M.; Myers, D. R.

    2008-12-01

    This report describes the evaluation of the relative performance of the complement of solar radiometers deployed at the National Renewable Energy Laboratory (NREL) Solar Radiation Research Laboratory (SRRL).

  13. Management of citation verification requests for multiple projects at Sandia National Laboratories

    SciTech Connect

    Crawford, C.S.

    1995-12-31

    Sandia National Laboratories` (SNL) Technical Library is now responsible for providing citation verification management support for all references cited in technical reports issued by the Nuclear Waste Management (NWM) Program. This paper dancing how this process is managed for the Yucca Mountain Site Characterization (YWP), Waste Isolation Pilot Plant (WIPP), Idaho National Engineering Laboratory (INEL), and Greater Confinement Disposal (GCD) projects. Since technical reports are the main product of these projects, emphasis is placed on meeting the constantly evolving needs of these customers in a timely and cost-effective manner.

  14. Characterizing groundwater at Oak Ridge National Laboratory hazardous waste sites

    SciTech Connect

    Wolf, D.A.; Tardiff, M.F.; Ketelle, R.H.

    1994-09-01

    The Oak Ridge National Laboratory (ORNL) is a large multipurpose US Department of Energy research facility located in East Tennessee on the Oak Ridge Reservation (ORR). The legacy of fifty years of operations at ORNL includes a variety of contaminated inactive facilities, research areas, and former waste disposal areas. At ORNL the majority of wastes were buried in shallow trenches above the water table. Groups of geographically contiguous areas, referred to as waste area groupings (WAGs), were defined for the Environmental Restoration Program so that a suitable monitoring system could be established. Thirteen WAGs at ORNL have been identified as potential sources of groundwater contamination. The main objective of the work described in this paper was to develop a systematic means for analyzing routine groundwater monitoring data from all WAGs to facilitate interpretation at a scale larger than individual monitoring points, to look for patterns that suggest general principles. In particular we wanted to determine whether specific geologic formations have discernable groundwater chemical signatures. The description of geologic formations in terms of their groundwater chemical signatures can be used in several practical ways. Positioning of down gradient sampling locations can be evaluated by comparing contaminant source and down gradient geochemistries. The geochemistry of contaminated seeps and springs can be used to suggest a likely stratigraphic association to the contaminant source. Also, the contaminant source location geochemistry and knowledge of the geologic unit`s potential for strata-bound flow can be used to predict exit pathways from contaminant sources.

  15. CULTURAL RESOURCE MANAGEMENT PLAN FOR BROOKHAVEN NATIONAL LABORATORY.

    SciTech Connect

    DAVIS, M.

    2005-04-01

    The Cultural Resource Management Plan (CRMP) for Brookhaven National Laboratory (BNL) provides an organized guide that describes or references all facets and interrelationships of cultural resources at BNL. This document specifically follows, where applicable, the format of the U.S. Department of Energy (DOE) Environmental Guidelines for Development of Cultural Resource Management Plans, DOE G 450.1-3 (9-22-04[m1]). Management strategies included within this CRMP are designed to adequately identify the cultural resources that BNL and DOE consider significant and to acknowledge associated management actions. A principal objective of the CRMP is to reduce the need for additional regulatory documents and to serve as the basis for a formal agreement between the DOE and the New York State Historic Preservation Officer (NYSHPO). The BNL CRMP is designed to be a ''living document.'' Each section includes identified gaps in the management plan, with proposed goals and actions for addressing each gap. The plan will be periodically revised to incorporate new documentation.

  16. Stirling engine research at national and university laboratories in Japan

    SciTech Connect

    Hane, G.J.; Hutchinson, R.A.

    1987-09-01

    Pacific Northwest Laboratory (PNL) reviewed research projects that are related to the development of Stirling engines and that are under way at Japanese national laboratories and universities. The research and development focused on component rather than on whole engine development. PNL obtained the information from a literature review and interviews conducted at the laboratories and universities. The universities have less equipment available and operate with smaller staffs for research than do the laboratories. In particular, the Mechanical Engineering Laboratory and the Aerospace Laboratory conduct high-quality component and fundamental work. Despite having less equipment, some of the researchers at the universities conduct high-quality fundamental research. As is typical in Japan, several of the university professors are very active in consulting and advisory capacities to companies engaged in Stirling engine development, and also with government and association advisory and technical committees. Contacts with these professors and selective examination of their research are good ways to keep abreast of Japanese Stirling developments.

  17. Oak Ridge National Laboratory Institutional Plan, FY 1991--FY 1996

    SciTech Connect

    Not Available

    1991-02-01

    The Oak Ridge National Laboratory -- one of DOE's major multiprogram laboratories -- focuses its resources on energy research and development (R D). To be able to meet these R D challenges, the Laboratory must achieve excellence in its operations relative to environmental, safety, and health (ES H) protection and to restore its aging facility infrastructure. ORNL's missions are carried out in compliance with all applicable ES H regulations. The Laboratory conducts applied R D in energy technologies -- in conservation; fission; magnetic fusion; health and environmental protection; waste management; renewable resources; and fossil energy. Experimental and theoretical research is undertaken to investigate fundamental problems in physical, chemical, materials, computational, biomedical, earth, and environmental sciences; to advance scientific knowledge; and to support energy technology R D. ORNL designs, builds, and operates unique research facilities for the benefit of university, industrial, and national laboratory researchers. The Laboratory serves as a catalyst in bringing national and international research elements together for important scientific and technical collaborations. ORNL helps to prepare the scientific and technical work force of the future by offering innovative and varied learning and R D experiences at the Laboratory for students and faculty from preschool level through postdoctoral candidates. The transfer of science and technology to US industries and universities is an integral component of ORNL's R D missions. ORNL also undertakes research and development for non-DOE sponsors when such work is synergistic with DOE mission. 66 figs., 55 tabs.

  18. A prototype catalogue: DOE National Laboratory technologies for infrastructure modernization

    SciTech Connect

    Currie, J.W.; Wilfert, G.L.; March, F.

    1990-01-01

    The purpose of this report is to provide the Office of Technology Assessment (OTA) with information about selected technologies under development in the Department of Energy (DOE) through its National Laboratory System and its Program Office operations. The technologies selected are those that have the potential to improve the performance of the nation's public works infrastructure. The product is a relational database that we refer to as a prototype catalogue of technologies.'' The catalogue contains over 100 entries of DOE-supported technologies having potential application to infrastructure-related problems. The work involved conceptualizing an approach, developing a framework for organizing technology information, and collecting samples of readily available data to be put into a prototype catalogue. In developing the catalogue, our objectives were to demonstrate the concept and provide readily available information to OTA. As such, the catalogue represents a preliminary product. The existing database is not exhaustive and likely represents only a fraction of relevant technologies developed by DOE. In addition, the taxonomy we used to classify technologies is based on the judgment of project staff and has received minimal review by individuals who have been involved in the development and testing of the technologies. Finally, end users will likely identify framework changes and additions that will strengthen the catalogue approach. The framework for the catalogue includes four components: a description of the technology, along with potential uses and other pertinent information; identification of the source of the descriptive information; identification of a person or group knowledgeable about the technology; and a classification of the described technology in terms of its type, application, life-cycle use, function, and readiness.

  19. Practical recommendations for strengthening national and regional laboratory networks in Africa in the Global Health Security era

    PubMed Central

    2016-01-01

    The role of national health laboratories in support of public health response has expanded beyond laboratory testing to include a number of other core functions such as emergency response, training and outreach, communications, laboratory-based surveillance and data management. These functions can only be accomplished by an efficient and resilient national laboratory network that includes public health, reference, clinical and other laboratories. It is a primary responsibility of the national health laboratory in the Ministry of Health to develop and maintain the national laboratory network in the country. In this article, we present practical recommendations based on 17 years of network development experience for the development of effective national laboratory networks. These recommendations and examples of current laboratory networks, are provided to facilitate laboratory network development in other states. The development of resilient, integrated laboratory networks will enhance each state’s public health system and is critical to the development of a robust national laboratory response network to meet global health security threats. PMID:28879137

  20. 36 CFR 1501.1 - Cross reference to National Park Service regulations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 36 Parks, Forests, and Public Property 3 2012-07-01 2012-07-01 false Cross reference to National... NATIONAL MEMORIAL TRUST GENERAL PROVISIONS § 1501.1 Cross reference to National Park Service regulations... (the Trust) adopts by cross reference the provisions of the National Park Service in 36 CFR chapter...

  1. 36 CFR 1501.1 - Cross reference to National Park Service regulations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 36 Parks, Forests, and Public Property 3 2014-07-01 2014-07-01 false Cross reference to National... NATIONAL MEMORIAL TRUST GENERAL PROVISIONS § 1501.1 Cross reference to National Park Service regulations... (the Trust) adopts by cross reference the provisions of the National Park Service in 36 CFR chapter...

  2. 76 FR 68179 - Environmental Management Site-Specific Advisory Board, Idaho National Laboratory

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-03

    ..., Idaho National Laboratory AGENCY: Department of Energy. ACTION: Notice of open meeting: correction... National Laboratory (76 FR 66917). This document makes a correction to that notice. FOR FURTHER...

  3. Assessment of the organizational structure and services of DOE National Laboratory Libraries

    SciTech Connect

    Dieden, K.

    1993-05-18

    This fieldwork assignment was created to assess the library and information services at the National Laboratories and to understand their organizational structures and the role of the library within those structures. The author`s goal was to collect the data and to evaluate the data and make appropriate recommendations for improving the quality of service at Lawrence Livermore National Laboratory Library. The objectives were: To develop a questionnaire which will be used in the reference interview; to contact a knowledgeable staff person at each facility and collect the information services data from that person; to identify innovative and unique services; to identify non-traditional methods of delivering information services to the scientific clientele; to obtain any user feedback on the services provided; and to identify the organization structure of each of the National laboratories and to determine the role of the library within those structures.

  4. 1994 Site Environmental Report Sandia National Laboratories Albuquerque, New Mexico

    SciTech Connect

    Shyr, L.J.; Wiggins, T.; White, B.B.

    1995-09-01

    This 1994 report contains data from routine radiological and nonradiological environmental monitoring activities. Summaries of significant environmental compliance programs in progress, such as National Environmental Policy Act documentation, environmental permits, environmental restoration, and various waste management programs for Sandia National Laboratories in Albuquerque, New Mexico, are included. The maximum off-site dose impact from air emissions was calculated to be 1.5 x 10{sup -4} millirem. The total population within a 50-mile radius of Sandia National Laboratories/New Mexico received an estimated collective dose of 0.012 person-rem during 1994 from the laboratories` operations. This report is prepared for the U.S. Department of Energy in compliance with DOE Order 5400.1.

  5. Comprehensive Reference Ranges for Hematology and Clinical Chemistry Laboratory Parameters Derived from Normal Nigerian Adults

    PubMed Central

    Miri-Dashe, Timzing; Osawe, Sophia; Tokdung, Monday; Daniel, Nenbammun; Choji, Rahila Pam; Mamman, Ille; Deme, Kurt; Damulak, Dapus; Abimiku, Alash’le

    2014-01-01

    Background Interpretation of laboratory test results with appropriate diagnostic accuracy requires reference or cutoff values. This study is a comprehensive determination of reference values for hematology and clinical chemistry in apparently healthy voluntary non-remunerated blood donors and pregnant women. Methods and findings Consented clients were clinically screened and counseled before testing for HIV, Hepatitis B, Hepatitis C and Syphilis. Standard national blood donors’ questionnaire was administered to consented blood donors. Blood from qualified volunteers was used for measurement of complete hematology and chemistry parameters. Blood samples were analyzed from a total of 383 participants, 124 (32.4%) males, 125 (32.6%) non-pregnant females and 134 pregnant females (35.2%) with a mean age of 31 years. Our results showed that the red blood cells count (RBC), Hemoglobin (HB) and Hematocrit (HCT) had significant gender difference (p = 0.000) but not for total white blood count (p>0.05) which was only significantly higher in pregnant verses non-pregnant women (p = 0.000). Hemoglobin and Hematocrit values were lower in pregnancy (P = 0.000). Platelets were significantly higher in females than men (p = 0.001) but lower in pregnant women (p = 0.001) with marked difference in gestational period. For clinical chemistry parameters, there was no significant difference for sodium, potassium and chloride (p>0.05) but gender difference exists for Bicarbonate (HCO3), Urea nitrogen, Creatinine as well as the lipids (p<0.05). Total bilirubin was significantly higher in males than females (p = 0.000). Significant differences exist for all chemistry parameters between pregnant and non-pregnant women in this study (p<0.05), except Amylase and total cholesterol (p>0.05). Conclusions Hematological and Clinical Chemistry reference ranges established in this study showed significant gender differences. Pregnant women also differed from non

  6. Overview of Sandia National Laboratories and Antenna Development Department

    SciTech Connect

    Brock, B.C.

    1994-04-01

    Sandia is a multiprogram R & D laboratory. It has responsibilities in the following areas: (1) defense programs; (2) energy and environment; and (3) work for others (DOD, NSA, etc.). In 1989, the National Competitiveness Technology Transfer Act added another responsibility -- contributions to industrial competitiveness. Sandia has two major laboratory locations, New Mexico and California, and two flight testing locations, Tonopah Test Range, Nevada and Kauai Test Facility, Hawaii. The last part of this talk was dedicated to antenna research at Sandia.

  7. National voluntary laboratory accreditation program: Energy efficient lighting products. Handbook

    SciTech Connect

    Galowin, L.S.; Hall, W.; Rossiter, W.J.

    1994-07-01

    The purpose of this handbook is to set out procedures and technical requirements for the National Voluntary Laboratory Accreditation Program (NVLAP) accreditation of laboratories which perform test methods covered by the Energy Efficient Lighting (EEL) Products program. It complements and supplements the NVLAP programmatic procedures and general requirements found in NIST Handbook 150 (PB94-178225). The interpretive comments and additional requirements contained in this handbook make the general NVLAP criteria specifically applicable to the EEL program.

  8. Radioactive target and source development at Argonne National Laboratory

    SciTech Connect

    Greene, J.P.; Ahmad, I.; Thomas, G.E.

    1992-10-01

    An increased demand for low-level radioactive targets has created the need for a laboratory dedicated to the production of these foils. A description is given of the radioactive target produced as well as source development work being performed at the Physics Division target facility of Argonne National Laboratory (ANL). Highlights include equipment used and the techniques employed. In addition, some examples of recent source preparation are given as well as work currently in progress.

  9. Radioactive target and source development at Argonne National Laboratory

    SciTech Connect

    Greene, J.P.; Ahmad, I.; Thomas, G.E.

    1992-01-01

    An increased demand for low-level radioactive targets has created the need for a laboratory dedicated to the production of these foils. A description is given of the radioactive target produced as well as source development work being performed at the Physics Division target facility of Argonne National Laboratory (ANL). Highlights include equipment used and the techniques employed. In addition, some examples of recent source preparation are given as well as work currently in progress.

  10. Site characteristics of Argonne National Laboratory in Illinois

    SciTech Connect

    Chang, Y.W.

    1995-01-01

    This report reviews the geology and topography of the Argonne National Laboratory, near Lemont, Illinois. It describes the thickness and stratigraphy of soils, glacial till, and bedrock in and adjacent to the laboratory and support facilities. Seismic surveys were also conducted through the area to help determine the values of seismic wave velocities in the glacial till which is important in determining the seismic hazard of the area. Borehole log descriptions are summarized along with information on area topography.

  11. Oak Ridge National Laboratory Next Generation Safeguards Initiative

    SciTech Connect

    Kirk, Bernadette Lugue; Eipeldauer, Mary D; Whitaker, J Michael

    2011-12-01

    In 2007, the Department of Energy's National Nuclear Security Administration (DOE/NNSA) Office of Nonproliferation and International Security (NA-24) completed a comprehensive review of the current and potential future challenges facing the international safeguards system. The review examined trends and events impacting the mission of international safeguards and the implications of expanding and evolving mission requirements on the legal authorities and institutions that serve as the foundation of the international safeguards system, as well as the technological, financial, and human resources required for effective safeguards implementation. The review's findings and recommendations were summarized in the report, 'International Safeguards: Challenges and Opportunities for the 21st Century (October 2007)'. One of the report's key recommendations was for DOE/NNSA to launch a major new program to revitalize the international safeguards technology and human resource base. In 2007, at the International Atomic Energy Agency's General Conference, then Secretary of Energy Samuel W. Bodman announced the newly created Next Generation Safeguards Initiative (NGSI). NGSI consists of five program elements: (1) Policy development and outreach; (2) Concepts and approaches; (3) Technology and analytical methodologies; (4) Human resource development; and (5) Infrastructure development. The ensuing report addresses the 'Human Resource Development (HRD)' component of NGSI. The goal of the HRD as defined in the NNSA Program Plan (November 2008) is 'to revitalize and expand the international safeguards human capital base by attracting and training a new generation of talent.' One of the major objectives listed in the HRD goal includes education and training, outreach to universities, professional societies, postdoctoral appointments, and summer internships at national laboratories. ORNL is a participant in the NGSI program, together with several DOE laboratories such as Pacific

  12. The pressing energy innovation challenge of the US National Laboratories

    NASA Astrophysics Data System (ADS)

    Anadon, Laura Diaz; Chan, Gabriel; Bin-Nun, Amitai Y.; Narayanamurti, Venkatesh

    2016-10-01

    Accelerating the development and deployment of energy technologies is a pressing challenge. Doing so will require policy reform that improves the efficacy of public research organizations and strengthens the links between public and private innovators. With their US$14 billion annual budget and unique mandates, the US National Laboratories have the potential to critically advance energy innovation, yet reviews of their performance find several areas of weak organizational design. Here, we discuss the challenges the National Laboratories face in engaging the private sector, increasing their contributions to transformative research, and developing culture and management practices to better support innovation. We also offer recommendations for how policymakers can address these challenges.

  13. Precision and manufacturing at the Lawrence Livermore National Laboratory

    NASA Technical Reports Server (NTRS)

    Saito, Theodore T.; Wasley, Richard J.; Stowers, Irving F.; Donaldson, Robert R.; Thompson, Daniel C.

    1994-01-01

    Precision Engineering is one of the Lawrence Livermore National Laboratory's core strengths. This paper discusses the past and present current technology transfer efforts of LLNL's Precision Engineering program and the Livermore Center for Advanced Manufacturing and Productivity (LCAMP). More than a year ago the Precision Machine Commercialization project embodied several successful methods of transferring high technology from the National Laboratories to industry. Currently, LCAMP has already demonstrated successful technology transfer and is involved in a broad spectrum of current programs. In addition, this paper discusses other technologies ripe for future transition including the Large Optics Diamond Turning Machine.

  14. Photographic as-builts for Argonne National Laboratory-West

    SciTech Connect

    Sherman, E.K.; Wiegand, C.V.

    1995-04-19

    Located 35 miles West of Idaho Falls, Idaho, Argonne National Laboratory-West operates a number of nuclear facilities for the Department of Energy (DOE) through the University of Chicago. Part of the present mission of Argonne National Laboratory-West includes shutdown of the EBR-II Reactor. In order to accomplish this task the Engineering-Drafting Department is exploring cost effective methods of providing as-building services. A new technology of integrating photographic images and AUTOCAD drawing files is considered one of those methods that shows promise.

  15. The changing role of the National Laboratories in materials research

    SciTech Connect

    Wadsworth, J.; Fluss, M.

    1995-06-02

    The role of the National Laboratories is summarized from the era of post World War II to the present time. The U.S. federal government policy for the National Laboratories and its influence on their materials science infrastructure is reviewed with respect to: determining overall research strategies, various initiatives to interact with industry (especially in recent years), building facilities that serve the nation, and developing leading edge research in the materials sciences. Despite reductions in support for research in the U.S. in recent years, and uncertainties regarding the specific policies for R&D in the U.S., there are strong roles for materials research at the National Laboratories. These roles will be centered on the abilities of the National Laboratories to field multidisciplinary teams, the use of unique cutting edge facilities, a focus on areas of strength within each of the labs, increased teaming and partnerships, and the selection of motivated research areas. It is hoped that such teaming opportunities will include new alliances with China, in a manner similar, perhaps, to those recently achieved between the U.S. and other countries.

  16. A study of technology transfer arrangements for national laboratories

    SciTech Connect

    Dorf, R.C.; Worthington, K.K.F.

    1987-08-25

    The transfer of technology to industrial partners and users is a complex task. The interactions between federal laboratories and industry and the market knowledge and ability to assess the needs of business users are beyond the charter of a federal laboratory. Therefore, new organizational mechanisms are required in order to obtain full commercial value from the laboratories' efforts. This paper will analyze cases of new ventures emerging from technology developed within federal laboratories. Seven models will be identified for technology transfer. These are the Information Dissemination Model, the Licensing Model, the Venture Capital Model, the Large Company-Joint Venture Model, the Incubator-Science Park Model, the Ferret Model, and the Agriculture Extension Model. Out of 13 laboratories, a Lawrence Livermore National Laboratory Partnership will be identified as having the greatest potential for successful implementation. The arrangement is a proposed consortium of the Lawrence Livermore National Laboratory, the University of California, venture capitalists, industrial firms, and federal and state agencies. 10 refs., 2 figs., 4 tabs.

  17. [Evaluation of the Malaria Evaluation Program in the national laboratory network in Colombia].

    PubMed

    García, Marisol; Mendoza, Nohora

    2002-06-01

    In 1995, the Parasitology Group--National Reference Laboratory--at the Instituto Nacional de Salud (INS) started a national malaria diagnosis program with the Public Health Laboratory Network which included training, indirect quality control, external quality control, technical assistance, advisory, reference and counter-reference, together with an annual review of the program. The purpose of this study was to carry out a three year (1997-1999) analysis of the program. In the indirect quality control program, average positive and negative concordances of 98% and 97%, respectively, and a kappa index of 0.95 were obtained by the state public health laboratories. In the external quality control program, an average concordance of 74.2% was obtained with an 89.2% participation of the registered laboratories. At the municipal level, the indirect quality control had an average concordance of 91.4% in positivity, 92.5% concordance in negativity, and a kappa index of 0.84. On the other hand, indirect quality control has been scarcely implemented by the state public health laboratories in the municipalities under their jurisdiction. In general, the program shows a good performance, despite some economic and conflict-related difficulties in the country, because people responsible at all levels for the Malaria Program have permanently carried out all other activities of the network, either according to annual programming or upon request. However, it is important to improve its coverage and the participation in its activities.

  18. Patient Dose Reference Levels for Interventional Radiology: A National Approach

    SciTech Connect

    Vano, Eliseo Sanchez, R.; Fernandez, J. M.; Gallego, J. J.; Verdu, J. F.; Garay, M. Gonzalez de; Azpiazu, A.; Segarra, A.; Hernandez, M. T.; Canis, M.; Diaz, F.; Moreno, F.; Palmero, J.

    2009-01-15

    A set of patient dose reference levels (RLs) for fluoroscopically guided interventional procedures was obtained in a survey launched by the National Society of Interventional Radiology (IR), involving 10 public hospitals, as recommended by the European Medical Exposures Directive. A sample of 1391 dose values (kerma area product [KAP]) was collected randomly during clinical procedures for seven of the most frequent procedures. Third quartiles of the KAP distributions were used to set the RLs. A regular quality control of the X-ray systems and a calibration of the dose meters were performed during the survey. The fluoroscopy time and total number of digital subtraction angiography images per procedure were also analyzed. The RL values proposed were 12 Gy cm{sup 2} for fistulography (hemodialysis access; sample of 180 cases), 73 Gy cm{sup 2} for lower limb arteriography (685 cases), 89 Gy cm{sup 2} for renal arteriography (55 cases), 80 Gy cm{sup 2} for biliary drainage (205 cases), 289 Gy cm{sup 2} for hepatic chemoembolization (151 cases), 94 Gy cm{sup 2} for iliac stent (70 cases), and 236 Gy cm{sup 2} for uterine embolization (45 cases). The provisional national RL values are lower than those obtained in a similar survey carried out in the United States from 2002 to 2004. These new values could be used to improve the practice of centers consistently working with doses higher than the RLs. This national survey also had a positive impact, as it helped increase the awareness of the members of the National Society of IR on a topic as crucial as patient dose values and programs on radiation protection.

  19. Determination of elements in National Bureau of Standards' geological Standard Reference Materials by neutron activation analysis

    SciTech Connect

    Graham, C.C.; Glascock, M.D.; Carni, J.J.; Vogt, J.R.; Spalding, T.G.

    1982-08-01

    Instrumental neutron activation analysis (INAA) and prompt gamma neutron activation analysis (PGNAA) have been used to determine elemental concentrations in two recently issued National Bureau of Standards (NBS) Standard Reference Materials (SRM's). The results obtained are in good agreement with the certified and information values reported by NBS for those elements in each material for which comparisons are available. Average concentrations of 35 elements in SRM 278 obsidian rock and 32 elements in SRM 688 basalt rock are reported for comparison with results that may be obtained by other laboratories.

  20. Natural Gas Storage Research at Savannah River National Laboratory

    SciTech Connect

    Anton, Don; Sulic, Martin; Tamburello, David A.

    2015-05-04

    As an alternative to imported oil, scientists at the Department of Energy’s Savannah River National Laboratory are looking at abundant, domestically sourced natural gas, as an alternative transportation fuel. SRNL is investigating light, inexpensive, adsorbed natural gas storage systems that may fuel the next generation of automobiles.

  1. Safe use of wire rope at a national laboratory

    SciTech Connect

    Stinnett, L.

    1982-08-01

    The safety of wire-rope cables used in hoists and cranes for heavy equipment handling at the Sandia National Laboratories, one experience with cable failure, and the inspection and servicing procedures used as safety precautions when dealing with wire rope are discussed. (LCL)

  2. Systems modeling at the Idaho National Engineering Laboratory

    NASA Astrophysics Data System (ADS)

    Bray, Michael A.

    1994-12-01

    This paper describes two experiences in systems modeling at the Idaho National Engineering Laboratory. These experiences reinforce key points that bear on the use of systems modeling in analyzing health-care issues. The first point is that mental models are a crucial part of systems. The second point is that simulation uncovers long-term consequences of existing assumptions.

  3. Management of hazardous wastes Lawrence Livermore National Laboratory

    SciTech Connect

    Jackson, C.S.

    1993-11-01

    Lawrence Livermore National Laboratory (LLNL), during the course of numerous research activities, generates hazardous, radioactive, and mixed (radioactive and hazardous) wastes. The management of these waste materials is highly regulated in the United States (US). This paper focuses on the hazardous waste regulations that limit and prescribe waste management at LLNL.

  4. Insects of the Idaho National Laboratory: A compilation and review

    Treesearch

    Nancy Hampton

    2005-01-01

    Large tracts of important sagebrush (Artemisia L.) habitat in southeastern Idaho, including thousands of acres at the Idaho National Laboratory (INL), continue to be lost and degraded through wildland fire and other disturbances. The roles of most insects in sagebrush ecosystems are not well understood, and the effects of habitat loss and alteration...

  5. Amchitka Island Environmental Analysis at Idaho National Laboratory

    SciTech Connect

    Gracy Elias; W. F. Bauer; J.G. Eisenmenger; C.C. Jensen; B.K. Schuetz; T. C. Sorensen; B.M. White; A. L. Freeman; M. E. McIlwain

    2005-08-01

    The Idaho National Laboratory (INL) provided support to Consortium for Risk Evaluation with Stakeholder Participation (CRESP) in their activities which is supported by the Department of Energy (DOE) to assess the impact of past nuclear testing at Amchitka Island on the ecosystemof the island and surrounding ocean. INL participated in this project in three phases, Phase 1, Phase 2 and Phase 3.

  6. Natural Gas Storage Research at Savannah River National Laboratory

    ScienceCinema

    Anton, Don; Sulic, Martin; Tamburello, David A.

    2016-07-12

    As an alternative to imported oil, scientists at the Department of Energy’s Savannah River National Laboratory are looking at abundant, domestically sourced natural gas, as an alternative transportation fuel. SRNL is investigating light, inexpensive, adsorbed natural gas storage systems that may fuel the next generation of automobiles.

  7. Sandia National Laboratories, California Environmental Management System program manual.

    SciTech Connect

    Larsen, Barbara L.

    2013-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 436.1.

  8. Aqueous Nitrate Recovery Line at Los Alamos National Laboratory

    SciTech Connect

    Finstad, Casey Charles

    2016-06-15

    This powerpoint is part of the ADPSM Plutonium Engineering Lecture Series, which is an opportunity for new hires at LANL to get an overview of work done at TA55. It goes into detail about the aqueous nitrate recovery line at Los Alamos National Laboratory.

  9. COMPUTATIONAL SCIENCE AT BROOKHAVEN NATIONAL LABORATORY: THREE SELECTED TOPICS.

    SciTech Connect

    DAVENPORT,J.W.DENG,Y.GLIMM,J.SAMULYAK,R.

    2003-09-15

    We present an overview of computational science at Brookhaven National Laboratory (BNL), with selections from three areas: fluids, nanoscience, and biology. The work at BNL in each of these areas is itself very broad, and we select a few topics for presentation within each of them.

  10. THE NATIONAL EXPOSURE RESEARCH LABORATORY'S CONSOLIDATED HUMAN ACTIVITY DATABASE

    EPA Science Inventory

    EPA's National Exposure Research Laboratory (NERL) has combined data from 12 U.S. studies related to human activities into one comprehensive data system that can be accessed via the Internet. The data system is called the Consolidated Human Activity Database (CHAD), and it is ...

  11. Strategic Plan for the ORD National Exposure Research Laboratory (NERL)

    EPA Science Inventory

    The National Exposure Research Laboratory (NERL) has a valued reputation for supporting the Agency’s mission of protecting human health and the environment with multidisciplinary expertise that brings cutting-edge research and technology to address critical exposure questions and...

  12. Amchitka Island Environmental Analysis at Idaho National Laboratory

    SciTech Connect

    Gracy Elias; W. F. Bauer; J.G. Eisenmenger; C.C. Jensen; B.K. Schuetz; T. C. Sorensen; B.M. White; A. L. Freeman; M. E. McIlwain

    2005-08-01

    The Idaho National Laboratory (INL) provided support to Consortium for Risk Evaluation with Stakeholder Participation (CRESP) in their activities which is supported by the Department of Energy (DOE) to assess the impact of past nuclear testing at Amchitka Island on the ecosystemof the island and surrounding ocean. INL participated in this project in three phases, Phase 1, Phase 2 and Phase 3.

  13. Strategic Plan for the ORD National Exposure Research Laboratory (NERL)

    EPA Science Inventory

    The National Exposure Research Laboratory (NERL) has a valued reputation for supporting the Agency’s mission of protecting human health and the environment with multidisciplinary expertise that brings cutting-edge research and technology to address critical exposure questions and...

  14. Sandia National Laboratories, California Environmental Management System program manual

    SciTech Connect

    Larsen, Barbara L.

    2014-04-01

    The Sandia National Laboratories, California (SNL/CA) Environmental Management System (EMS) Program Manual documents the elements of the site EMS Program. The SNL/CA EMS Program conforms to the International Standard on Environmental Management Systems, ISO 14001:2004 and Department of Energy (DOE) Order 436.1.

  15. Waste management study: Process development at Lawrence Livermore National Laboratory

    SciTech Connect

    Not Available

    1984-12-01

    This report presents the results of an evaluation of the present Toxic Waste Control Operations at the Lawrence Livermore National Laboratory, evaluates the technologies most applicable to the treatment of toxic and hazardous wastes and presents conceptual designs of processes for the installation of a new decontamination and waste treatment facility (DWTF) for future treatment of these wastes.

  16. Essen and the National Physical Laboratory's atomic clock

    NASA Astrophysics Data System (ADS)

    Henderson, Dale

    2005-06-01

    To commemorate the fiftieth anniversary of the development of the first atomic frequency standard, we present some notes about the work of Louis Essen at the National Physical Laboratory. In addition, we publish below some personal recollections of Essen on his work, which have previously been available only on the Internet (http://www.btinternet.com/~time.lord/TheAtomicClock.htm).

  17. Successful neural network projects at the Idaho National Engineering Laboratory

    SciTech Connect

    Cordes, G.A.

    1991-01-01

    This paper presents recent and current projects at the Idaho National Engineering Laboratory (INEL) that research and apply neural network technology. The projects are summarized in the paper and their direct application to space reactor power and propulsion systems activities is discussed. 9 refs., 10 figs., 3 tabs.

  18. THE NATIONAL EXPOSURE RESEARCH LABORATORY'S COMPREHENSIVE HUMAN ACTIVITY DATABASE

    EPA Science Inventory

    EPA's National Exposure Research Laboratory (NERL) has combined data from nine U.S. studies related to human activities into one comprehensive data system that can be accessed via the world-wide web. The data system is called CHAD-Consolidated Human Activity Database-and it is ...

  19. THE NATIONAL EXPOSURE RESEARCH LABORATORY'S CONSOLIDATED HUMAN ACTIVITY DATABASE

    EPA Science Inventory

    EPA's National Exposure Research Laboratory (NERL) has combined data from 12 U.S. studies related to human activities into one comprehensive data system that can be accessed via the Internet. The data system is called the Consolidated Human Activity Database (CHAD), and it is ...

  20. THE NATIONAL EXPOSURE RESEARCH LABORATORY'S COMPREHENSIVE HUMAN ACTIVITY DATABASE

    EPA Science Inventory

    EPA's National Exposure Research Laboratory (NERL) has combined data from nine U.S. studies related to human activities into one comprehensive data system that can be accessed via the world-wide web. The data system is called CHAD-Consolidated Human Activity Database-and it is ...

  1. DESALINATION AND WATER TREATMENT RESEARCH AT SANDIA NATIONAL LABORATORIES.

    SciTech Connect

    Rigali, Mark J.; Miller, James E.; Altman, Susan J.; Biedermann, Laura; Brady, Patrick Vane.; Kuzio, Stephanie P.; Nenoff, Tina M.; Rempe, Susan

    2016-11-01

    Water is the backbone of our economy - safe and adequate supplies of water are vital for agriculture, industry, recreation, and human consumption. While our supply of water today is largely safe and adequate, we as a nation face increasing water supply challenges in the form of extended droughts, demand growth due to population increase, more stringent health-based regulation, and competing demands from a variety of users. To meet these challenges in the coming decades, water treatment technologies, including desalination, will contribute substantially to ensuring a safe, sustainable, affordable, and adequate water supply for the United States. This overview documents Sandia National Laboratories' (SNL, or Sandia) Water Treatment Program which focused on the development and demonstration of advanced water purification technologies as part of the larger Sandia Water Initiative. Projects under the Water Treatment Program include: (1) the development of desalination research roadmaps (2) our efforts to accelerate the commercialization of new desalination and water treatment technologies (known as the 'Jump-Start Program),' (3) long range (high risk, early stage) desalination research (known as the 'Long Range Research Program'), (4) treatment research projects under the Joint Water Reuse & Desalination Task Force, (5) the Arsenic Water Technology Partnership Program, (6) water treatment projects funded under the New Mexico Small Business Administration, (7) water treatment projects for the National Energy Technology Laboratory (NETL) and the National Renewable Energy Laboratory (NREL), (8) Sandia- developed contaminant-selective treatment technologies, and finally (9) current Laboratory Directed Research and Development (LDRD) funded desalination projects.

  2. Ergonomic assessments of three Idaho National Engineering Laboratory cafeterias

    SciTech Connect

    Ostrom, L.T.; Romero, H.A.; Gilbert, B.G.; Wilhelmsen, C.A.

    1993-05-01

    The Idaho National Engineering Laboratory is a Department of Energy facility that performs a variety of engineering and research projects. EG&G Idaho is the prime contractor for the laboratory and, as such, performs the support functions in addition to technical, research, and development functions. As a part of the EG&G Idaho Industrial Hygiene Initiative, ergonomic assessments were conducted at three Idaho National Engineering Laboratory Cafeterias. The purposes of the assessments were to determine whether ergonomic problems existed in the work places and, if so, to make recommendations to improve the work place and task designs. The study showed there were ergonomic problems in all three cafeterias assessed. The primary ergonomic stresses observed included wrist and shoulder stress in the dish washing task, postural stress in the dish washing and food preparation tasks, and back stress in the food handling tasks.

  3. Ergonomic assessments of three Idaho National Engineering Laboratory cafeterias

    SciTech Connect

    Ostrom, L.T.; Romero, H.A.; Gilbert, B.G.; Wilhelmsen, C.A.

    1993-01-01

    The Idaho National Engineering Laboratory is a Department of Energy facility that performs a variety of engineering and research projects. EG G Idaho is the prime contractor for the laboratory and, as such, performs the support functions in addition to technical, research, and development functions. As a part of the EG G Idaho Industrial Hygiene Initiative, ergonomic assessments were conducted at three Idaho National Engineering Laboratory Cafeterias. The purposes of the assessments were to determine whether ergonomic problems existed in the work places and, if so, to make recommendations to improve the work place and task designs. The study showed there were ergonomic problems in all three cafeterias assessed. The primary ergonomic stresses observed included wrist and shoulder stress in the dish washing task, postural stress in the dish washing and food preparation tasks, and back stress in the food handling tasks.

  4. Airbags to Martian Landers: Analyses at Sandia National Laboratories

    SciTech Connect

    Gwinn, K.W.

    1994-03-01

    A new direction for the national laboratories is to assist US business with research and development, primarily through cooperative research and development agreements (CRADAs). Technology transfer to the private sector has been very successful as over 200 CRADAs are in place at Sandia. Because of these cooperative efforts, technology has evolved into some new areas not commonly associated with the former mission of the national laboratories. An example of this is the analysis of fabric structures. Explicit analyses and expertise in constructing parachutes led to the development of a next generation automobile airbag; which led to the construction, testing, and analysis of the Jet Propulsion Laboratory Mars Environmental Survey Lander; and finally led to the development of CAD based custom garment designs using 3D scanned images of the human body. The structural analysis of these fabric structures is described as well as a more traditional example Sandia with the test/analysis correlation of the impact of a weapon container.

  5. [Los Alamos National Laboratory industrial applications and technology transfer

    SciTech Connect

    Not Available

    1992-09-30

    In October 1989, the Los Alamos Economic Development Corporation (LAEDC) entered into a contract with the Industrial Applications office (IAO) of Los Alamos National Laboratory (LANL) whereby the LAEDC was to provide support services to IAO. More specifically, according to the Statement of Work in this contract The Los Alamos Economic Development Corporation shall assist the Los Alamos National Laboratory Industrial Applications Office in establishing and strengthening connections between potential entrepreneurs at the Laboratory and the business assistance community throughout New Mexico, directed toward enhancing the number, of successful start up businesses spinning off the Laboratory's technology base.'' As part of this contract and subsequent modifications thereof, the LAEDC was to perform seven tasks: 1. Provide business planning assistance to potential entrepreneurs. 2. (Assist IAO in preparing and distributing) informational materials on technology transfer. 3. (Organize and manage) meetings and seminars on technology transfer and entrepreneurship. 4. Identify new opportunities for technology transfer. 5. (Identify and implement programs for the) recognition of Laboratory Entrepreneurs. 6. Training Lab personnel, in the area of technology transfer and Laboratory industrial interactions. 7. Review and summarize prior New Mexico economic development studies. The purpose of this report, is to summarize the accomplishments of the LAEDC under its contract with IAO, and to fulfill its reporting requirements. This report covers the period from October 1989 to September 1992.

  6. National laboratory policies and plans in sub-Saharan African countries: gaps and opportunities

    PubMed Central

    van der Broek, Ankie; Jansen, Christel; de Bruijn, Hilde; Schultsz, Constance

    2017-01-01

    Background The 2008 Maputo Declaration calls for the development of dedicated national laboratory policies and strategic plans supporting the enhancement of laboratory services in response to the long-lasting relegation of medical laboratory systems in sub-Saharan Africa. Objectives This study describes the extent to which laboratories are addressed in the national health policies and plans created directly following the 2008 momentum for laboratory strengthening. Method National health policies and plans from 39 sub-Saharan African countries, valid throughout and beyond 31 December 2010 were collected in March 2012 and analysed during 2013. Results Laboratories were addressed by all countries. Human resources were the most addressed topic (38/39) and finances and budget were the least addressed (< 5/39). Countries lagging behind in national laboratory strategic planning at the end of 2013 (17/39) were more likely to be francophone countries located in West-Central Africa (13/17) and have historically low HIV prevalence. The most common gaps anticipated to compromise the implementation of the policies and plans were the disconnect between policies and plans, under-developed finance sections and monitoring and evaluating frameworks, absence of points of reference to define gaps and shortages, and inappropriate governance structure. Conclusion The availability of laboratory policy and plan implementation can be improved by strictly applying a more standardised methodology for policy development, using harmonised norms to set targets for improvement and intensifying the establishment of directorates of laboratory services directly under the authority of Ministries of Health. Horizontal programmes such as the Global Health Security Agenda could provide the necessary impulse to take the least advanced countries on board. PMID:28879152

  7. The National Teacher Enhancement Program (K-8) coordinated by the Oak Ridge National Laboratory

    SciTech Connect

    Richmond, C.R.

    1991-01-01

    Teachers need help, not harassment. So do the establishments in which teachers practice their profession. Community resources must be marshalled to provide help to local schools and teachers. In 1990 the National Science Foundation (NSF) established a unique educational activity named the National Teacher Enhancement Program (NTEP). NSF took advantage of the Department of Energy (DOE) sponsored educational programs and resources at several large DOE contractor labs that had had prior experience with DOE supported teacher enhancement programs. While DOE concentrated on teacher enhancement activities for secondary teachers, the NSF concentrated on teachers from grades K-8. The Oak Ridge National Laboratory (ORNL) is the lead organization for both administering and coordinating the grant. Other participating laboratories are Argonne National Laboratory (ANL), Fermi National Accelerator Laboratory (FERMI), Battelle-Pacific Northwest Laboratory (PNL), Lawrence Livermore Laboratory (LLNL) with some support functions provided by Brookhaven National Laboratory (BNL) and the Oak Ridge Associated Universities (ORAU). The program calls for a three week duration workshop to be conducted at each lab followed by in-service training and other activities during the year. The NSF/NTEP protocol calls for networking among the participating organizations and some of the teachers. An assessment effort is also an integral part of the program. 2 refs.

  8. Origins and development of the National Laboratory System for public health testing.

    PubMed

    Astles, J Rex; White, Vanessa A; Williams, Laurina O

    2010-01-01

    Although not recognized as such, a National Laboratory System (NLS) has existed since the inception of public health laboratory (PHL) testing more than a century ago. The NLS has always relied upon the participation of clinical laboratories, both to report test results that represent public health threats and to submit specimens and isolates to PHLs for additional or confirmatory testing. Historically, a number of factors have hindered the strengthening of the relationships between clinical laboratories and PHLs, but the reality of bioterrorism and subsequent focus on strengthening public-private relationships has stimulated the development of a more robust NLS. Since 2002, there has been substantial strengthening of the NLS through the sharing of lessons learned from several demonstration projects. There is a growing emphasis on defining critical elements of the NLS, including the State Public Health Laboratory System (SPH Laboratory System) and the functions of the Laboratory Program Advisor, a position that every state should have at the center of its laboratory system's capacity-building. Additional strengthening of the NLS is occurring through (1) national biennial measurement of state PHLs' abilities to meet the Core Functions and Capabilities of State PHLs, (2) the new Laboratory System Improvement Program (L-SIP) for the SPH Laboratory System, and (3) sharing ideas to integrate and improve the SPH Laboratory System (e.g., using the L-SIP Online Resource Center). Public health emergencies, such as the recent H1N1 epidemic, illustrate and reinforce the need for a strong NLS within which federal, public health, and clinical (i.e., hospital and private reference) laboratories function in close collaboration.

  9. Prototype prosperity-diversity game for the Laboratory Development Division of Sandia National Laboratories

    SciTech Connect

    VanDevender, P.; Berman, M.; Savage, K.

    1996-02-01

    The Prosperity Game conducted for the Laboratory Development Division of National Laboratories on May 24--25, 1995, focused on the individual and organizational autonomy plaguing the Department of Energy (DOE)-Congress-Laboratories` ability to manage the wrenching change of declining budgets. Prosperity Games are an outgrowth and adaptation of move/countermove and seminar War Games. Each Prosperity Game is unique in that both the game format and the player contributions vary from game to game. This particular Prosperity Game was played by volunteers from Sandia National Laboratories, Eastman Kodak, IBM, and AT&T. Since the participants fully control the content of the games, the specific outcomes will be different when the team for each laboratory, Congress, DOE, and the Laboratory Operating Board (now Laboratory Operations Board) is composed of executives from those respective organizations. Nevertheless, the strategies and implementing agreements suggest that the Prosperity Games stimulate cooperative behaviors and may permit the executives of the institutions to safely explore the consequences of a family of DOE concert.

  10. Women in Physics: The Next Generation At Our National Laboratories

    NASA Astrophysics Data System (ADS)

    Krossa, Cheryl

    2001-04-01

    Just as a house must be built on a strong foundation, with each subsequent course of bricks placed upon those that went before, the advances of women in physics are built upon the accomplishments of those women who have gone before. How are we preparing for the next course of bricks? Where will the next generation of women in physics come from, and how are these women being prepared to take their place among your ranks? The United States Department of Energy is helping to mold the next generation of women in physics, in part, through the efforts of its fifteen national laboratories: Argonne, Brookhaven, Fermi, Idaho, Lawrence Berkeley, Lawrence Livermore, Los Alamos, Oak Ridge, Pacific Northwest, Princeton Plasma Physics, Sandia, National Energy Technology Laboratory, National Renewable Energy Laboratory, Stanford Linear Accelerator Center, and Thomas Jefferson National Accelerator Facility. This presentation will showcase some of the creative and innovative approaches these institutions are taking, from outreach to girls in elementary schools to executive appointments, to secure not only this nation's future, but that of women in physics.

  11. Photovoltaic Calibrations at the National Renewable Energy Laboratory and Uncertainty Analysis Following the ISO 17025 Guidelines

    SciTech Connect

    Emery, Keith

    2016-09-01

    The measurement of photovoltaic (PV) performance with respect to reference conditions requires measuring current versus voltage for a given tabular reference spectrum, junction temperature, and total irradiance. This report presents the procedures implemented by the PV Cell and Module Performance Characterization Group at the National Renewable Energy Laboratory (NREL) to achieve the lowest practical uncertainty. A rigorous uncertainty analysis of these procedures is presented, which follows the International Organization for Standardization (ISO) Guide to the Expression of Uncertainty in Measurement. This uncertainty analysis is required for the team’s laboratory accreditation under ISO standard 17025, “General Requirements for the Competence of Testing and Calibration Laboratories.” The report also discusses additional areas where the uncertainty can be reduced.

  12. SENIORLAB: a prospective observational study investigating laboratory parameters and their reference intervals in the elderly

    PubMed Central

    Risch, Martin; Nydegger, Urs; Risch, Lorenz

    2017-01-01

    Abstract Background: In clinical practice, laboratory results are often important for making diagnostic, therapeutic, and prognostic decisions. Interpreting individual results relies on accurate reference intervals and decision limits. Despite the considerable amount of resources in clinical medicine spent on elderly patients, accurate reference intervals for the elderly are rarely available. The SENIORLAB study set out to determine reference intervals in the elderly by investigating a large variety of laboratory parameters in clinical chemistry, hematology, and immunology. Methods/design: The SENIORLAB study is an observational, prospective cohort study. Subjectively healthy residents of Switzerland aged 60 years and older were included for baseline examination (n = 1467), where anthropometric measurements were taken, medical history was reviewed, and a fasting blood sample was drawn under optimal preanalytical conditions. More than 110 laboratory parameters were measured, and a biobank was set up. The study participants are followed up every 3 to 5 years for quality of life, morbidity, and mortality. The primary aim is to evaluate different laboratory parameters at age-related reference intervals. The secondary aims of this study include the following: identify associations between different parameters, identify diagnostic characteristics to diagnose different circumstances, identify the prevalence of occult disease in subjectively healthy individuals, and identify the prognostic factors for the investigated outcomes, including mortality. Discussion: To obtain better grounds to justify clinical decisions, specific reference intervals for laboratory parameters of the elderly are needed. Reference intervals are obtained from healthy individuals. A major obstacle when obtaining reference intervals in the elderly is the definition of health in seniors because individuals without any medical condition and any medication are rare in older adulthood. Reference

  13. Pacific Northwest National Laboratory institutional plan FY 1998--2002

    SciTech Connect

    1997-12-01

    Pacific Northwest National Laboratory`s core mission is to deliver environmental science and technology in the service of the nation and humanity. Through basic research the lab creates fundamental knowledge of natural, engineered, and social systems that is the basis for both effective environmental technology and sound public policy. They solve legacy environmental problems by delivering technologies that remedy existing environmental hazards, they address today`s environmental needs with technologies that prevent pollution and minimize waste, and they are laying the technical foundation for tomorrow`s inherently clean energy and industrial processes. The lab also applies their capabilities to meet selected national security, energy, and human health needs; strengthen the US economy; and support the education of future scientists and engineers. The paper summarizes individual research activities under each of these areas.

  14. The International Space Station: A National Science Laboratory

    NASA Technical Reports Server (NTRS)

    Giblin, Timothy W.

    2011-01-01

    After more than a decade of assembly missions and on the heels of the final voyage of Space Shuttle Discovery, the International Space Station (ISS) has reached assembly completion. With visiting spacecraft now docking with the ISS on a regular basis, the Station now serves as a National Laboratory to scientists back on Earth. ISS strengthens relationships among NASA, other Federal entities, higher educational institutions, and the private sector in the pursuit of national priorities for the advancement of science, technology, engineering, and mathematics. In this lecture we will explore the various areas of research onboard ISS to promote this advancement: (1) Human Research, (2) Biology & Biotechnology, (3) Physical & Material Sciences, (4) Technology, and (5) Earth & Space Science. The ISS National Laboratory will also open new paths for the exploration and economic development of space.

  15. A data automation system at Los Alamos National Laboratory.

    SciTech Connect

    Betts, S. E.; Schneider, C. M.; Pickrell, M. M.

    2001-01-01

    Idaho National Engineering and Environmental Laboratory (INEEL) has developed an automated computer program, Data Review Expert System (DRXS), for reviewing nondestructive assay (NDA) data. DRXS significantly reduces the data review time needed to meet characterization requirements for the Waste Isolation Pilot Plant (WIPP). Los Alamos National Laboratory (LANL) is in the process of developing a computer program, Software System Logic for Intelligent Certification (SSLIC), to automate other tasks associa ted with characterization of Transuranic Waste (TRU) samples. LANL has incorporated a version of DRXS specific to LANL's isotopic data into SSLIC. This version of SSLIC was audited by the National Transuranic Program on October, 24, 2001. This paper will present the results of the audit, and discuss future plans for SSLIC including the integration on the INEELLANL developed Rule Editor.

  16. Piloting a national laboratory electronic programme status reporting system.

    PubMed

    Cassim, Naseem; Coetzee, Lindi; Motlonye, Bahule; Mpele, Nobantu; Glencross, Deborah K

    2013-01-01

    The NHLS performs close to 4 million CD4 tests per annum for the public sector in South Africa through a network of 60 CD4 testing laboratories. CD4 laboratory data provides an assessment of the number of patients on ART and HIV-positive patients in the pre-ART wellness programs. This study aims to develop a laboratory based Comprehensive Care, Management and Treatment of HIV and AIDS (CCMT) programme status reporting system for CD4 testing at three health facilities in the Ekurhuleni health district using a newly developed CCMT request form, the Laboratory Information System (LIMS) and Corporate Data Warehouse (CDW). The study will generate monitoring and evaluation data to assist in the management of health facilities through a national electronic corporate data warehouse.

  17. Los Alamos National Laboratory support to IAEA environmental safeguards

    SciTech Connect

    Steiner, Robert E; Dry, Don E; Roensch, Fred R; Kinman, Will S; Roach, Jeff L; La Mont, Stephen P

    2010-12-01

    The nuclear and radiochemistry group provides sample preparation and analysis support to the International Atomic Energy Agency (IAEA) Network of Analytical Laboratories (NWAL). These analyses include both non-destructive (alpha and gamma-ray spectrometry) and destructive (thermal ionization mass spectrometry and inductively coupled plasma mass spectrometry) methods. On a bi-annual basis the NWAL laboratories are invited to meet to discuss program evolution and issues. During this meeting each participating laboratory summarizes their efforts over the previous two years. This presentation will present Los Alamos National Laboratories efforts in support of this program. Data showing results from sample and blank analysis will be presented along with capability enhancement and issues that arose over the previous two years.

  18. The Laser Safety Program at Los Alamos National Laboratory

    SciTech Connect

    Hyer, R.

    1997-02-01

    The Laser Safety Program at the Los Alamos National Laboratory was formalized in April, 1991, with the publication of a document, {open_quotes}Lasers,{close_quotes} modeled on the ANSIZ136.1 standard. This program has received such wide acceptance by the laser community and line managers that the original Laser Safety Program document has become a Laboratory standard on lasers. As a benchmark of the success of this program is that the Laboratory has experienced no disabling eye injuries because of laser operations since July, 1990, to be compared with a disabling laser eye injury that used to average one every eighteen months prior to the time the formal program was established. The Laboratory Laser Safety Program and program elements will be presented and discussed.

  19. Los Alamos National Laboratory: 21st century solutions to urgent national challenges

    SciTech Connect

    Mcbranch, Duncan

    2008-01-01

    Los Alamos National Laboratory has been called upon to meet urgent national challenges for more than 65 years. The people, tools, and technologies at Los Alamos are a world class resource that has proved decisive through our history, and are needed in the future. We offer expertise in nearly every science, technology, and engineering discipline, a unique integrated capability for large-scale computing and experimentation, and the proven ability to deliver solutions involving the most complex and difficult technical systems. This white paper outlines some emerging challenges and why the nation needs Los Alamos, the premier National Security Science Laboratory, to meet these challenges.

  20. Real-time laboratory exercises to test contingency plans for classical swine fever: experiences from two national laboratories.

    PubMed

    Koenen, F; Uttenthal, A; Meindl-Böhmer, A

    2007-12-01

    In order to adequately and efficiently handle outbreaks of contagious diseases such as classical swine fever (CSF), foot and mouth disease or highly pathogenic avian influenza, competent authorities and the laboratories involved have to be well prepared and must be in possession of functioning contingency plans. These plans should ensure that in the event of an outbreak access to facilities, equipment, resources, trained personnel, and all other facilities needed for the rapid and efficient eradication of the outbreak is guaranteed, and that the procedures to follow are well rehearsed. It is essential that these plans are established during 'peace-time' and are reviewed regularly. This paper provides suggestions on how to perform laboratory exercises to test preparedness and describes the experiences of two national reference laboratories for CSF. The major lesson learnt was the importance of a well-documented laboratory contingency plan. The major pitfalls encountered were shortage of space, difficulties in guaranteeing biosecurity and sufficient supplies of sterile equipment and consumables. The need for a standardised laboratory information management system, that is used by all those involved in order to reduce the administrative load, is also discussed.

  1. Croatian national reference Y-STR haplotype database.

    PubMed

    Mršić, Gordan; Gršković, Branka; Vrdoljak, Andro; Popović, Maja; Valpotić, Ivica; Anđelinović, Šimun; Stenzl, Vlastimil; Ehler, Edvard; Urban, Ludvik; Lacković, Gordana; Underhill, Peter; Primorac, Dragan

    2012-07-01

    A reference Y-chromosome short tandem repeat (STR) haplotype database is needed for Y-STR match interpretation as well as for national and regional characterization of populations. The aim of this study was to create a comprehensive Y-STR haplotype database of the Croatian contemporary population and to analyze substructure between the five Croatian regions. We carried out a statistical analysis of the data from previously performed genetic analyses collected during routine forensic work by the Forensic Science Centre "Ivan Vučetić". A total of 1,100 unrelated men from eastern, western, northern, southern and central Croatia were selected for the purpose of this study. Y-STRs were typed using the AmpFISTR Yfiler PCR amplification kit. Analysis of molecular variance calculated with the Y chromosome haplotype reference database online analysis tool included 16 population samples with 20,247 haplotypes. A total of 947 haplotypes were recorded, 848 of which were unique (89.5%). Haplotype diversity was 0.998, with the most frequent haplotype found in 9 of 1,100 men (0.82%). Locus diversity varied from 0.266 for DYS392 to 0.868 for DYS385. Discrimination capacity was 86.1%. Our results suggested high level of similarity among regional subpopulations within Croatia, except for mildly different southern Croatia. Relative resemblance was found with Bosnia and Herzegovina and Serbia. Whit Atheys' Haplogroup Predictor was used to estimate the frequencies of Y-chromosome haplogroups. I2a, R1a, E1b1b and R1b haplogroups were most frequent in all Croatian regions. These results are important in forensics and contribute to the population genetics and genetic background of the contemporary Croatian population.

  2. Conceptual design of new metrology laboratories for the National Physical Laboratory, United Kingdom

    NASA Astrophysics Data System (ADS)

    Manning, Christopher J.

    1994-10-01

    The National Physical Laboratory is planning to house the Division of Mechanical and Optical Metrology and the Division of Material Metrology in a new purpose built laboratory building on its site at Teddington, London, England. The scientific staff were involved in identifying and agreeing the vibration performance requirements of the conceptual design. This was complemented by an extensive surgery of vibration levels within the existing facilities and ambient vibration studies at the proposed site. At one end of the site there is significant vibration input from road traffic. Some of the test equipment is also in itself a source of vibration input. These factors, together with normal occupancy inputs, footfalls and door slams, and a highly serviced building led to vibration being dominant in influencing the structural form. The resulting structural concept comprises three separate structural elements for vibration and geotechnical reasons. The laboratories most sensitive to disturbance by vibration are located at the end of the site farthest from local roads on a massive ground bearing slab. Less sensitive laboratories and those containing vibration sources are located on a massive slab in deep, piled foundations. A common central plant area is located alongside on its own massive slab. Medium sensitivity laboratories and offices are located at first floor level on a reinforced concrete suspended floor of maximum stiffness per unit mass. The whole design has been such as to permit upgrading of areas, eg office to laboratory; laboratory to `high sensitivity' laboratory, to cater for changes in future use of the building.

  3. GCR Simulator Reference Field and a Spectral Approach for Laboratory Simulation

    NASA Technical Reports Server (NTRS)

    Slaba, Tony C.; Blattnig, Steve R.; Norbury, John W.; Rusek, Adam; La Tessa, Chiara; Walker, Steven A.

    2015-01-01

    The galactic cosmic ray (GCR) simulator at the NASA Space Radiation Laboratory (NSRL) is intended to deliver the broad spectrum of particles and energies encountered in deep space to biological targets in a controlled laboratory setting. In this work, certain aspects of simulating the GCR environment in the laboratory are discussed. Reference field specification and beam selection strategies at NSRL are the main focus, but the analysis presented herein may be modified for other facilities. First, comparisons are made between direct simulation of the external, free space GCR field and simulation of the induced tissue field behind shielding. It is found that upper energy constraints at NSRL limit the ability to simulate the external, free space field directly (i.e. shielding placed in the beam line in front of a biological target and exposed to a free space spectrum). Second, variation in the induced tissue field associated with shielding configuration and solar activity is addressed. It is found that the observed variation is likely within the uncertainty associated with representing any GCR reference field with discrete ion beams in the laboratory, given current facility constraints. A single reference field for deep space missions is subsequently identified. Third, an approach for selecting beams at NSRL to simulate the designated reference field is presented. Drawbacks of the proposed methodology are discussed and weighed against alternative simulation strategies. The neutron component and track structure characteristics of the simulated field are discussed in this context.

  4. Progress in photovoltaic module calibration: results of a worldwide intercomparison between four reference laboratories

    NASA Astrophysics Data System (ADS)

    Dirnberger, D.; Kräling, U.; Müllejans, H.; Salis, E.; Emery, K.; Hishikawa, Y.; Kiefer, K.

    2014-10-01

    Measurement results from a worldwide intercomparison of photovoltaic module calibrations are presented. Four photovoltaic reference laboratories in the USA, Japan and Europe with different traceability chains, measurement equipment and procedures, and uncertainty estimation concepts, participated. Seven photovoltaic modules of different technologies were measured (standard and high-efficiency crystalline silicon, cadmium telluride, single and double-junction amorphous and micromorph silicon). The measurement results from all laboratories and for all devices agreed well. Maximum power for the crystalline silicon samples was within ±1.3% for all thin-film modules roughly within ±3%, which is an improvement compared to past intercomparisons. The agreement between the results was evaluated using a weighted mean as a reference value, which considers results-specific uncertainty, instead of the widely used unweighted arithmetic mean. A further statistical analysis of all deviations between results and the corresponding reference mean showed that the uncertainties estimated by the participating laboratories were realistic, with a slight tendency towards being too conservative. The observed deviations of results from the reference mean concerned mainly short-circuit current and fill factor. Module stability was monitored through repeated measurements at Fraunhofer ISE before and after measurements at each of the other participating laboratories. Based on these re-measurements, stability problems that occurred for some thin-film modules and influenced the results were analyzed and explained in detail.

  5. Clinical isolates and laboratory reference Candida species and strains have varying abilities to form biofilms.

    PubMed

    Alnuaimi, Ali D; O'Brien-Simpson, Neil M; Reynolds, Eric C; McCullough, Michael J

    2013-11-01

    Candida biofilms are a major virulence trait for this yeast. In this study, the biofilm-forming ability of the major medically important clinical and laboratory reference strains was compared. Biofilms were quantified using traditional methods, that is, crystal violet (CV), tetrazolium (XTT) reduction and colony-forming unit assays (CFU), and two new methods: an automated cell counter (ACC) and biofilm suspension turbidity (BST) method. Biofilms could be categorized based on biofilm biomass (high, medium and low) and growth state (high and low). Candida albicans genotypes, A, B and C, showed medium biofilm mass and low growth rate, and only one C. albicans laboratory strain, ATCC MYA-2719, matched this biofilm category. Of all non-albicans Candida species tested, only Candida dubliniensis and Candida glabrata laboratory and clinical isolates had similar biofilm development. The ACC and BST methods for measuring biofilm significantly correlated with CV and CFU biofilm mass measurements. Thus, biofilm mass can be rapidly assessed using biofilm disruptive/cellular nondestructive methods allowing yeast biofilm cells to be used for further analysis. In conclusion, Candida laboratory reference strains and clinical isolates have been shown to form biofilms at different rates; hence for validity, the selection of laboratory reference strains in biofilm studies may be critical for virulence assessment.

  6. Post Irradiation Capabilities at the Idaho National Laboratory

    SciTech Connect

    J. L. Schulthess; K. E. Rosenberg

    2011-05-01

    The U.S. Department of Energy (DOE), Office of Nuclear Energy (NE) oversees the efforts to ensure nuclear energy remains a viable option for the United States. A significant portion of these efforts are related to post-irradiation examinations (PIE) of highly activated fuel and materials that are subject to the extreme environment inside a nuclear reactor. As the lead national laboratory, Idaho National Laboratory (INL) has a rich history, experience, workforce and capabilities for performing PIE. However, new advances in tools and techniques for performing PIE now enable understanding the performance of fuels and materials at the nano-scale and smaller level. Examination at this level is critical since this is the scale at which irradiation damage occurs. The INL is on course to adopt these advanced tools and techniques to develop a comprehensive nuclear fuels and materials characterization capability that is unique in the world. Because INL has extensive PIE capabilities currently in place, a strong foundation exist to build upon as new capabilities are implemented and work load increases. In the recent past, INL has adopted significant capability to perform advanced PIE characterization. Looking forward, INL is planning for the addition of two facilities that will be built to meet the stringent demands of advanced tools and techniques for highly activated fuels and materials characterization. Dubbed the Irradiated Materials Characterization Laboratory (IMCL) and Advanced Post Irradiation Examination Capability , these facilities are next generation PIE laboratories designed to perform the work of PIE that cannot be performed in current DOE facilities. In addition to physical capabilities, INL has recently added two significant contributors to the Advanced Test Reactor-National Scientific User Facility (ATR-NSUF), Oak Ridge National Laboratory and University of California, Berkeley.

  7. Replacement of the Idaho National Engineering Laboratory Health Physics Instrumentation Laboratory

    SciTech Connect

    1995-05-01

    The DOE-Idaho Operations Office (DOE-ID) has prepared an environmental assessment (EA) on the replacement of the Idaho National Engineering Laboratory Health Physics Instrumentation Laboratory at the Idaho National Engineering Laboratory (INEL). The purpose of this project is to replace the existing Health Physics Instrumentation Laboratory (HPIL) with a new facility to provide a safe environment for maintaining and calibrating radiation detection instruments used at the Idaho National Engineering Laboratory. The existing HPIL facility provides portable health physics monitoring instrumentation and direct reading dosimetry procurement, maintenance and calibration of radiation detection instruments, and research and development support-services to the INEL and others. However, the existing facility was not originally designed for laboratory activities and does not provide an adequate, safe environment for calibration activities. The EA examined the potential environmental impacts of the proposed action and evaluated reasonable alternatives, including the no action alternative in accordance with the Council on Environmental Quality (CEQ) Regulations (40 CFR Parts 1500-1508). Based on the environmental analysis in the attached EA, the proposed action will not have a significant effect on the human environment within the meaning of the National Environmental Policy Act (NEPA) and 40 CFR Parts 1508.18 and 1508.27. The selected action (the proposed alternative) is composed of the following elements, each described or evaluated in the attached EA on the pages referenced. The proposed action is expected to begin in 1997 and will be completed within three years: design and construction of a new facility at the Central Facility Area of the INEL; operation of the facility, including instrument receipt, inspections and repairs, precision testing and calibration, and storage and issuance. The selected action will result in no significant environmental impacts.

  8. Sandia National Laboratories Institutional Plan FY1994--1999

    SciTech Connect

    Not Available

    1993-10-01

    This report presents a five year plan for the laboratory. This plan takes advantage of the technical strengths of the lab and its staff to address issues of concern to the nation on a scope much broader than Sandia`s original mission, while maintaining the general integrity of the laboratory. The plan proposes initiatives in a number of technologies which overlap the needs of its customers and the strengths of its staff. They include: advanced manufacturing technology; electronics; information and computational technology; transportation energy technology and infrastructure; environmental technology; energy research and technology development; biomedical systems engineering; and post-cold war defense imperatives.

  9. Brookhaven National Laboratory site environmental report for calendar year 1990

    SciTech Connect

    Miltenberger, R.P.; Royce, B.A.; Naidu, J.R.

    1992-01-01

    Brookhaven National Laboratory (BNL) carries out basic and applied research in the following fields: high-energy nuclear and solid state physics; fundamental material and structure properties and the interactions of matter; nuclear medicine, biomedical and environmental sciences; and selected energy technologies. In conducting these research activities, it is Laboratory policy to protect the health and safety of employees and the public, and to minimize the impact of BNL operations on the environment. This document is the BNL environmental report for the calendar year 1990 for the safety and Environmental Protection division and corners topics on effluents, surveillance, regulations, assessments, and compliance.

  10. Argonne National Laboratory-East evolution of solid waste management

    SciTech Connect

    Trychta, K.; McHenry, J.; Thuot, J.

    1996-07-01

    The purpose of this report is to provide the reader with a basic understanding of Argonne National Laboratory`s current general refuse disposal and material recycling programs, how they were developed, and where they are going. In order to better understand the current situation, a brief description of the facilities past practices is explained. ANL is a multi-program research and development center owned by DOE and operated by the University of Chicago. Argonne`s primary facilities are on a 1,700 acre site, 27 miles southwest of Chicago. Fifty-seven major buildings house approximately 4,500 employees at the site.

  11. Idaho National Engineering Laboratory Sewer System Upgrade Project. Environmental Assessment

    SciTech Connect

    Not Available

    1994-04-01

    The Department of Energy (DOE) has prepared an environmental assessment for a proposed Sewer System Upgrade Project at the Idaho National Engineering Laboratory (INEL) near Idaho Falls, Idaho. The proposed action would include activities conducted at the Central Facilities Area, Test Reactor Area, and the Containment Test Facility at the Test Area North at INEL. The proposed action would consist of replacing or remodeling the existing sewage treatment plants at the Central Facilities Area, Test Reactor Area, and Containment Test Facility. Also, a new sewage testing laboratory would be constructed at the Central Facilities Area. Finally, the proposed action would include replacing, repairing, and/or adding sewer lines in areas where needed.

  12. Lawrence Berkeley National Laboratory 1997 Site Environmental Report Vol. II

    SciTech Connect

    Thorson, Patrick.

    1998-09-30

    Volume II of the Site Environmental Report for 1997 is published by Ernest Orlando Lawrence Berkeley National Laboratory as a supplemental appendix to the report printed in volume I. Volume II contains the environmental monitoring and sampling data used to generate summary results in the main report for routine and nonroutine activities at the Laboratory (except for groundwater sampling data). Data presented in volume II are given in Systeme International (SI) units. The list below categorizes the volume II data sections with corresponding summary result tables in volume I: Stack Air, Ambient Air, Rainwater, Creeks, Creek Baseline Study, Hydraugers, Lakes, Stormwater, Sewer, Fixed Treatment Units, Soil, Sediment, Vegetation.

  13. Brookhaven National Laboratory site report for calendar year 1988

    SciTech Connect

    Miltenberger, R.P.; Royce, B.A.; Naidu, J.R.

    1989-06-01

    Brookhaven National Laboratory (BNL) is managed by Associated Universities Inc. (AUI). AUI was formed in 1946 by a group of nine universities whose purpose was to create and manage a laboratory in the Northeast in order to advance scientific research in areas of interest to universities, industry, and government. On January 31, 1947, the contract for BNL was approved by the Manhattan District of the Army Corps of Engineers and BNL was established on the former Camp Upton army camp. 54 refs., 21 figs., 78 tabs.

  14. 78 FR 66964 - International Space Station National Laboratory Advisory Committee; Charter Renewal

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-07

    ... SPACE ADMINISTRATION International Space Station National Laboratory Advisory Committee; Charter Renewal AGENCY: National Aeronautics and Space Administration (NASA). ACTION: Notice of renewal of the charter of the International Space Station National Laboratory Advisory Committee. SUMMARY: Pursuant to...

  15. Defining laboratory reference values and decision limits: populations, intervals, and interpretations.

    PubMed

    Boyd, James C

    2010-01-01

    This article provides a brief overview of various approaches that may be utilized for the analysis of human semen test results. Reference intervals are the most widely used tool for the interpretation of clinical laboratory results. Reference interval development has classically relied on concepts elaborated by the International Federation of Clinical Chemistry Expert Panel on Reference Values during the 1980s. These guidelines involve obtaining and classifying samples from a healthy population of at least 120 individuals and then identifying the outermost 5% of observations to use in defining limits for two-sided or one-sided reference intervals. More recently, decision limits based on epidemiological outcome analysis have also been introduced to aid in test interpretation. The reference population must be carefully defined on the basis of the intended clinical use of the underlying test. To determine appropriate reference intervals for use in male fertility assessment, a reference population of men with documented time to pregnancy of < 12 months would be most suitable. However, for epidemiological assessment of semen testing results, a reference population made up of unselected healthy men would be preferred. Although reference and decision limits derived for individual semen analysis test results will undoubtedly be the interpretational tools of choice in the near future, in the long term, multivariate methods for the interpretation of semen analysis alone or in combination with information from the female partner seem to represent better means for assessing the likelihood of achieving a successful pregnancy in a subfertile couple.

  16. Defining laboratory reference values and decision limits: populations, intervals, and interpretations

    PubMed Central

    Boyd, James C.

    2010-01-01

    This article provides a brief overview of various approaches that may be utilized for the analysis of human semen test results. Reference intervals are the most widely used tool for the interpretation of clinical laboratory results. Reference interval development has classically relied on concepts elaborated by the International Federation of Clinical Chemistry Expert Panel on Reference Values during the 1980s. These guidelines involve obtaining and classifying samples from a healthy population of at least 120 individuals and then identifying the outermost 5% of observations to use in defining limits for two-sided or one-sided reference intervals. More recently, decision limits based on epidemiological outcome analysis have also been introduced to aid in test interpretation. The reference population must be carefully defined on the basis of the intended clinical use of the underlying test. To determine appropriate reference intervals for use in male fertility assessment, a reference population of men with documented time to pregnancy of < 12 months would be most suitable. However, for epidemiological assessment of semen testing results, a reference population made up of unselected healthy men would be preferred. Although reference and decision limits derived for individual semen analysis test results will undoubtedly be the interpretational tools of choice in the near future, in the long term, multivariate methods for the interpretation of semen analysis alone or in combination with information from the female partner seem to represent better means for assessing the likelihood of achieving a successful pregnancy in a subfertile couple. PMID:20111086

  17. Services of the CDRH X-ray calibration laboratory and their traceability to National Standards

    SciTech Connect

    Cerra, F.; Heaton, H.T.

    1993-12-31

    The X-ray Calibration Laboratory (XCL) of the Center for Devices and Radiological Health (CDRH) provides calibration services for the Food and Drug Administration (FDA). The instruments calibrated are used by FDA and contract state inspectors to verify compliance with federal x-ray performance standards and for national surveys of x-ray trends. In order to provide traceability of measurements, the CDRH XCL is accredited by the National Voluntary Laboratory Accreditation Program (NVLAP) for reference, diagnostic, and x-ray survey instrument calibrations. In addition to these accredited services, the CDRH XCL also calibrates non-invasive kVp meters in single- and three-phase x-ray beams, and thermoluminescent dosimeter (TLD) chips used to measure CT beam profiles. The poster illustrates these services and shows the traceability links back to the National Standards.

  18. Customer satisfaction assessment at the Pacific Northwest National Laboratory

    SciTech Connect

    DN Anderson; ML Sours

    2000-03-23

    The Pacific Northwest National Laboratory (PNNL) is developing and implementing a customer satisfaction assessment program (CSAP) to assess the quality of research and development provided by the laboratory. This report presents the customer survey component of the PNNL CSAP. The customer survey questionnaire is composed of two major sections: Strategic Value and Project Performance. Both sections contain a set of questions that can be answered with a 5-point Likert scale response. The strategic value section consists of five questions that are designed to determine if a project directly contributes to critical future national needs. The project Performance section consists of nine questions designed to determine PNNL performance in meeting customer expectations. A statistical model for customer survey data is developed and this report discusses how to analyze the data with this model. The properties of the statistical model can be used to establish a gold standard or performance expectation for the laboratory, and then to assess progress. The gold standard is defined using laboratory management input--answers to four questions, in terms of the information obtained from the customer survey: (1) What should the average Strategic Value be for the laboratory project portfolio? (2) What Strategic Value interval should include most of the projects in the laboratory portfolio? (3) What should average Project Performance be for projects with a Strategic Value of about 2? (4) What should average Project Performance be for projects with a Strategic Value of about 4? To be able to provide meaningful answers to these questions, the PNNL customer survey will need to be fully implemented for several years, thus providing a link between management perceptions of laboratory performance and customer survey data.

  19. The laboratory efficiencies initiative: partnership for building a sustainable national public health laboratory system.

    PubMed

    Ridderhof, John C; Moulton, Anthony D; Ned, Renée M; Nicholson, Janet K A; Chu, May C; Becker, Scott J; Blank, Eric C; Breckenridge, Karen J; Waddell, Victor; Brokopp, Charles

    2013-01-01

    Beginning in early 2011, the Centers for Disease Control and Prevention and the Association of Public Health Laboratories launched the Laboratory Efficiencies Initiative (LEI) to help public health laboratories (PHLs) and the nation's entire PHL system achieve and maintain sustainability to continue to conduct vital services in the face of unprecedented financial and other pressures. The LEI focuses on stimulating substantial gains in laboratories' operating efficiency and cost efficiency through the adoption of proven and promising management practices. In its first year, the LEI generated a strategic plan and a number of resources that PHL directors can use toward achieving LEI goals. Additionally, the first year saw the formation of a dynamic community of practitioners committed to implementing the LEI strategic plan in coordination with state and local public health executives, program officials, foundations, and other key partners.

  20. The Laboratory Efficiencies Initiative: Partnership for Building a Sustainable National Public Health Laboratory System

    PubMed Central

    Moulton, Anthony D.; Ned, Renée M.; Nicholson, Janet K.A.; Chu, May C.; Becker, Scott J.; Blank, Eric C.; Breckenridge, Karen J.; Waddell, Victor; Brokopp, Charles

    2013-01-01

    Beginning in early 2011, the Centers for Disease Control and Prevention and the Association of Public Health Laboratories launched the Laboratory Efficiencies Initiative (LEI) to help public health laboratories (PHLs) and the nation's entire PHL system achieve and maintain sustainability to continue to conduct vital services in the face of unprecedented financial and other pressures. The LEI focuses on stimulating substantial gains in laboratories' operating efficiency and cost efficiency through the adoption of proven and promising management practices. In its first year, the LEI generated a strategic plan and a number of resources that PHL directors can use toward achieving LEI goals. Additionally, the first year saw the formation of a dynamic community of practitioners committed to implementing the LEI strategic plan in coordination with state and local public health executives, program officials, foundations, and other key partners. PMID:23997300

  1. Adult Hematology and Clinical Chemistry Laboratory Reference Ranges in a Zimbabwean Population

    PubMed Central

    Mandozana, Gibson; Tinago, Willard; Nhando, Nehemiah; Mgodi, Nyaradzo M.; Bwakura-Dangarembizi, Mutsawashe F.

    2016-01-01

    Background Laboratory reference ranges used for clinical care and clinical trials in various laboratories in Zimbabwe were derived from textbooks and research studies conducted more than ten years ago. Periodic verification of these ranges is essential to track changes over time. The purpose of this study was to establish hematology and chemistry laboratory reference ranges using more rigorous methods. Methods A community-based cross-sectional study was carried out in Harare, Chitungwiza, and Mutoko. A multistage sampling technique was used. Samples were transported from the field for analysis at the ISO15189 certified University of Zimbabwe-University of California San Francisco Central Research Laboratory. Hematology and clinical chemistry reference ranges lower and upper reference limits were estimated at the 2.5th and 97.5th percentiles respectively. Results A total of 769 adults (54% males) aged 18 to 55 years were included in the analysis. Median age was 28 [IQR: 23–35] years. Males had significantly higher red cell counts, hemoglobin, hematocrit, and mean corpuscular hemoglobin compared to females. Females had higher white cell counts, platelets, absolute neutrophil counts, and absolute lymphocyte counts compared to males. There were no gender differences in eosinophils, monocytes, and absolute basophil count. Males had significantly higher levels of urea, sodium, potassium, calcium, creatinine, amylase, total protein, albumin and liver enzymes levels compared to females. Females had higher cholesterol and lipase compared with males. There are notable differences in the white cell counts, neutrophils, cholesterol, and creatinine kinase when compared with the currently used reference ranges. Conclusion Data from this study provides new country specific reference ranges which should be immediately adopted for routine clinical care and accurate monitoring of adverse events in research studies. PMID:27812172

  2. Adult Hematology and Clinical Chemistry Laboratory Reference Ranges in a Zimbabwean Population.

    PubMed

    Samaneka, Wadzanai P; Mandozana, Gibson; Tinago, Willard; Nhando, Nehemiah; Mgodi, Nyaradzo M; Bwakura-Dangarembizi, Mutsawashe F; Munjoma, Marshall W; Gomo, Zvenyika A R; Chirenje, Zvavahera M; Hakim, James G

    2016-01-01

    Laboratory reference ranges used for clinical care and clinical trials in various laboratories in Zimbabwe were derived from textbooks and research studies conducted more than ten years ago. Periodic verification of these ranges is essential to track changes over time. The purpose of this study was to establish hematology and chemistry laboratory reference ranges using more rigorous methods. A community-based cross-sectional study was carried out in Harare, Chitungwiza, and Mutoko. A multistage sampling technique was used. Samples were transported from the field for analysis at the ISO15189 certified University of Zimbabwe-University of California San Francisco Central Research Laboratory. Hematology and clinical chemistry reference ranges lower and upper reference limits were estimated at the 2.5th and 97.5th percentiles respectively. A total of 769 adults (54% males) aged 18 to 55 years were included in the analysis. Median age was 28 [IQR: 23-35] years. Males had significantly higher red cell counts, hemoglobin, hematocrit, and mean corpuscular hemoglobin compared to females. Females had higher white cell counts, platelets, absolute neutrophil counts, and absolute lymphocyte counts compared to males. There were no gender differences in eosinophils, monocytes, and absolute basophil count. Males had significantly higher levels of urea, sodium, potassium, calcium, creatinine, amylase, total protein, albumin and liver enzymes levels compared to females. Females had higher cholesterol and lipase compared with males. There are notable differences in the white cell counts, neutrophils, cholesterol, and creatinine kinase when compared with the currently used reference ranges. Data from this study provides new country specific reference ranges which should be immediately adopted for routine clinical care and accurate monitoring of adverse events in research studies.

  3. Nuclear energy related capabilities at Sandia National Laboratories

    SciTech Connect

    Pickering, Susan Y.

    2014-02-01

    Sandia National Laboratories' technology solutions are depended on to solve national and global threats to peace and freedom. Through science and technology, people, infrastructure, and partnerships, part of Sandia's mission is to meet the national needs in the areas of energy, climate and infrastructure security. Within this mission to ensure clean, abundant, and affordable energy and water is the Nuclear Energy and Fuel Cycle Programs. The Nuclear Energy and Fuel Cycle Programs have a broad range of capabilities, with both physical facilities and intellectual expertise. These resources are brought to bear upon the key scientific and engineering challenges facing the nation and can be made available to address the research needs of others. Sandia can support the safe, secure, reliable, and sustainable use of nuclear power worldwide by incorporating state-of-the-art technologies in safety, security, nonproliferation, transportation, modeling, repository science, and system demonstrations.

  4. Role of the "National Reference Centre for Genetically Modified Organisms (GMO) detection" in the official control of food and feed.

    PubMed

    Ciabatti, I; Marchesi, U; Froiio, A; Paternò, A; Ruggeri, M; Amaddeo, D

    2005-08-01

    The National Reference Centre for Genetically Modified Organisms (GMO) detection was established in 2002 within the Istituto Zooprofilattico Sperimentale Lazio e Toscana, with the aim of providing scientific and technical support to the National Health System and to the Ministry of Health within the scope of the regulation of GMO use in food and feed.The recently adopted EU legislation on GMOs (Regulation CE no. 1829/2003 and no. 1830/2003) introduced more rigorous procedures for the authorisation, labelling and analytical control of food and feed consisting, containing or derived from GMOs. The National Reference Centre, besides its institutional tasks as one of the laboratories of the Italian National Health System, collects and analyses data and results of the national official control of GMOs; carries out scientific research aimed at developing, improving, validating and harmonising detection and quantification methods, in cooperation with other scientific institutions, the Community Reference Laboratory and within the European Network of GMOs laboratories (ENGL); collaborates with the Ministry of Health in the definition of control programmes and promotes educational and training initiatives. Objectives defined for 2004-2006, activities in progress and goals already achieved are presented.

  5. Los Alamos National Laboratory compliance with cultural resource management legislation

    SciTech Connect

    Olinger, C.E.; Rea, K.H.

    1984-01-01

    Cultural resources management is one aspect of NEPA-induced legislation increasingly affecting federal land managers. A number of regulations, some of them recent, outline management criteria for protecting cultural resources on federal land. Nearly all construction projects at the 11,135 hectare Los Alamos National Laboratory in northern New Mexico are affected by cultural resource management requirements. A substantial prehistoric Puebloan population occupied the Laboratory area from the 13th to the early 16th centuries. Grazing, timbering, and homesteading followed Indian occupation. Therefore, archaeological and historical ruins and artifacts are abundant. The Laboratory has developed a cultural resources management program which meets both legal and project planning requirements. The program operates in coordination with the New Mexico State Historical Preservation Office. Major elements of the Laboratory program are illustrated by a current project involving relocation of a homesteader's cabin located on land required for a major new facility. The Laboratory cultural resource management program couples routine oversight of all engineering design projects with onsite resource surveys and necessary mitigation prior to construction. The Laboratory has successfully protected major archaeological and historical ruins, although some problems remain. The cultural resource program is intended to be adjustable to new needs. A cultural resource management plan will provide long-term management guidance.

  6. Welcome to Los Alamos National Laboratory: A premier national security science laboratory

    SciTech Connect

    Wallace, Terry

    2012-06-25

    Dr Wallace presents visitors with an overview of LANL's national security science mission: stockpile stewardship, protecting against the nuclear threat, and energy security & emerging threats, which are underpinned by excellence in science/technology/engineering capabilities. He shows visitors a general Lab overview of budget, staff, and facilities before providing a more in-depth look at recent Global Security accomplishments and current programs.

  7. A virtual national laboratory for reengineering clinical translational science.

    PubMed

    Dilts, David M; Rosenblum, Daniel; Trochim, William M

    2012-01-25

    Clinical research is burdened by inefficiencies and complexities, with a poor record of trial completion, none of which is desirable. The Clinical and Translational Science Award (CTSA) Consortium, including more than 60 clinical research institutions, supports a unified national effort to become, in effect, a virtual national laboratory designed to identify, implement, evaluate, and extend process improvements across all parts of clinical research, from conception to completion. If adequately supported by academic health centers, industry, and funding agencies, the Consortium could become a test bed for improvements that can dramatically reduce wasteful complexity, thus increasing the likelihood of clinical trial completion.

  8. 1987 environmental monitoring report, Sandia National Laboratories, Livermore, California

    SciTech Connect

    Devlin, T.K.

    1988-04-01

    Sandia National Labortories conduct various research activities related to Department of Energy interests which have the potential for release of hazardous materials or radionuclides to the environment. A strict environmental control program places maximum emphasis on limiting releases. The environmental monitoring program conducted by Lawrence Livermore National Laboratory and augmented by Sandia is designed to measure the performance of the environmental controls. The program includes analysis of air, water, soil, vegetation, sewer effluent, ground water, and foodstuffs for various toxic, hazardous, or radioactive materials. Based on these studies, the releases of materials of concern at Sandia during 1987 were well below applicable Department of Energy standards. 8 refs., 3 figs., 12 tabs.

  9. Bradbury science museum: your window to Los Alamos National Laboratory

    SciTech Connect

    Deck, Linda Theresa

    2009-03-05

    The Bradbury Science Museum is the public's window to Los Alamos National Laboratory and supports the Community Program Office's mission to develop community support to accomplish LANL's national security and science mission. It does this by stimulating interest in and increasing basic knowledge of science and technology in northern New Mexico audiences, and increasing public understanding and appreciation of how LANL science and technology solve our global problems. In performing these prime functions, the Museum also preserves the history of scientific accomplishment at the Lab by collecting and preserving artifacts of scientific and historical importance.

  10. Parabolic Trouogh Optical Characterization at the National Renewable Energy Laboratory

    SciTech Connect

    Wendelin, T. J.

    2005-01-01

    Solar parabolic trough power plant projects are soon to be implemented in the United States and internationally. In addition to these new projects, parabolic trough power plants totaling approximately 350 MW already exist within the United States and have operated for close to 20 years. As such, the status of the technology exists within several different phases. Theses phases include R&D, manufacturing and installation, and operations and maintenance. One aspect of successful deployment of this technology is achieving and maintaining optical performance. Different optical tools are needed to assist in improving initial designs, provide quality control during manufacture and assembly, and help maintain performance during operation. This paper discusses several such tools developed at SunLab (a joint project of the National Renewable Laboratory and Sandia National Laboratories) for these purposes. Preliminary testing results are presented. Finally, plans for further tool development are discussed.

  11. Sandia National Laboratories, California proposed CREATE facility environmental baseline survey.

    SciTech Connect

    Catechis, Christopher Spyros

    2013-10-01

    Sandia National Laboratories, Environmental Programs completed an environmental baseline survey (EBS) of 12.6 acres located at Sandia National Laboratories/California (SNL/CA) in support of the proposed Collaboration in Research and Engineering for Advanced Technology and Education (CREATE) Facility. The survey area is comprised of several parcels of land within SNL/CA, County of Alameda, California. The survey area is located within T 3S, R 2E, Section 13. The purpose of this EBS is to document the nature, magnitude, and extent of any environmental contamination of the property; identify potential environmental contamination liabilities associated with the property; develop sufficient information to assess the health and safety risks; and ensure adequate protection for human health and the environment related to a specific property.

  12. Idaho National Laboratory Annual Report FY 2013 LDRD Project Summaries

    SciTech Connect

    Dena Tomchak

    2014-03-01

    The FY 2013 LDRD Annual Report is a compendium of the diverse research performed to develop and ensure the INL’s technical capabilities support the current and future DOE missions and national research priorities. LDRD is essential to INL—it provides a means for the Laboratory to maintain scientific and technical vitality while funding highly innovative, high-risk science and technology research and development (R&D) projects. The program enhances technical capabilities at the Laboratory, providing scientific and engineering staff with opportunities to explore proof-of-principle ideas, advanced studies of innovative concepts, and preliminary technical analyses. Established by Congress in 1991, the LDRD Program proves its benefit each year through new programs, intellectual property, patents, copyrights, national and international awards, and publications.

  13. Smoking patterns among Los Alamos National Laboratory employees

    SciTech Connect

    Mahoney, M.C.; Wilkinson, G.S.

    1987-06-01

    Smoking patterns among 5507 employees at Los Alamos National Laboratory were investigated for those who underwent physical examinations by occupational physicians from 1978 to 1983. More male than female employees smoked, although differences in smoking rates between the sexes were not as large as differences observed for national smoking rates. Employees over 40 were more likely to smoke than younger employees, males consumed more cigarettes than did females, and Anglo employees smoked more cigarettes than did Hispanic employees. Highly educated employees smoked less than did less-educated workers, and staff members exhibited the lowest rates of smoking. Smoking cessation programs for Laboratory employees should be directed toward those subpopulations with the highest rates of smoking. 31 refs., 8 figs., 1 tab.

  14. Summer Research Internship Program (FY94) Brookhaven National Laboratory

    SciTech Connect

    Toler, L.T.; Indusi, J.P.

    1995-02-01

    The Summer Research Internship Program is a new program that allows high school teachers to participate and assist scientific staff at national laboratories in specific research assignments. This participation allows the high school teachers to become familiar with new technology and have ``hands-on`` experience with experiments and equipment which utilize both mathematics and science skills. Teachers also have the opportunity to advance their new and well-developed software. This enlightenment and experience is brought back into their schools and classrooms in the hopes that their peers and students will realize the excitement that knowledge and education in the areas of mathematics and science can bring. The Safeguards, Safety and Nonproliferation Division of the Department of Advanced Technology at Brookhaven National Laboratory utilized five high school teachers during FY94 in various projects. The project assignments and internship activities are outlined in this paper.

  15. Los Alamos National Laboratory capability reviews - FY 2011 status

    SciTech Connect

    Springer, Everett P

    2011-01-12

    Capability reviews are the Los Alamos National Laboratory approach to assess the quality of its science, technology, and engineering (STE), and its integration across the Laboratory. There are seven capability reviews in FY 2011 reviews. The Weapons Science and Engineering review will be replaced by the National Nuclear Security Administration's Predictive Science Panel for 2011 . Beginning in 2011, third-year LORD projects will be reviewed by capability review committees rather than the first-year LORD projects that have been performed for the last three years. This change addresses concerns from committees about reviewing a project before it had made any substantive progress. The current schedule, and chairs for the 2011 capability reviews is presented. The three-year cycle (2011-2013) for capability reviews are presented for planning purposes.

  16. Malignant melanoma incidence at the Los Alamos National Laboratory.

    PubMed

    Acquavella, J F; Tietjen, G L; Wilkinson, G S; Key, C R; Voelz, G L

    1982-04-17

    In an analysis of melanoma incidence for 1969 to 1978 among 11 308 workers at the Los Alamos National Laboratory in New Mexico 6 cases were detected in the total cohort, in which 5.69 cases would be expected (standardised incidence ratio [SIR] = 105; 90% confidence interval [CI] = 51,198) on the basis of incidence rates for the State of New Mexico, specific for age, sex, and ethnic origin. Among the White non-Hispanic men, 3 cases were detected, whereas 4.4 would be expected. The associated SIR of 68 (90% CI = 23, 163) does not suggest excess melanoma incidence in this subcohort. A direct comparison with Statewide incidence rates gave similar results. These results do not agree with the threefold excess of malignant melanoma incidence found among White male employees at the Lawrence Livermore National Laboratory.

  17. BROOKHAVEN NATIONAL LABORATORY SITE ENVIRONMENTAL REPORT FOR CALENDAR YEAR 1994.

    SciTech Connect

    NAIDU,J.R.; ROYCE,B.A.

    1995-05-01

    This report documents the results of the Environmental Monitoring Program at Brookhaven National Laboratory and presents summary information about environmental compliance for 1994. To evaluate the effect of Brookhaven National Laboratory's operations on the local environment, measurements of direct radiation, and a variety of radionuclides and chemical compounds in ambient air, soil, sewage effluent, surface water, groundwater, fauna and vegetation were made at the Brookhaven National Laboratory site and at sites adjacent to the Laboratory. Brookhaven National Laboratory's compliance with all applicable guides, standards, and limits for radiological and nonradiological emissions and effluents to the environment were evaluated. Among the permitted facilities, two instances of pH exceedances were observed at recharge basins, possibly related to rain-water run-off to these recharge basins. Also, the discharge from the Sewage Treatment Plant to the Peconic River exceeded. on ten occasions, one each for fecal coliform and 5-day Biochemical Oxygen Demand (avg.) and eight for ammonia nitrogen. The ammonia and Biochemical Oxygen Demand exceedances were attributed to the cold winter and the routine cultivation of the sand filter beds which resulted in the hydraulic overloading of the filter beds and the possible destruction of nitrifying bacteria. The on-set of warm weather and increased aeration of the filter beds via cultivation helped to alleviate this condition. The discharge of fecal coliform may also be linked to this occurrence, in that the increase in fecal coliform coincided with the increased cultivation of the sand filter beds. The environmental monitoring data has identified site-specific contamination of groundwater and soil. These areas are subject to Remedial Investigation/Feasibility Studies under the Inter Agency Agreement. Except for the above, the environmental monitoring data has continued to demonstrate that compliance was achieved with applicable

  18. Argonne National Laboratory institutional plan FY 2001--FY 2006.

    SciTech Connect

    Beggs, S.D.

    2000-12-07

    This Institutional Plan describes what Argonne management regards as the optimal future development of Laboratory activities. The document outlines the development of both research programs and support operations in the context of the nation's R and D priorities, the missions of the Department of Energy (DOE) and Argonne, and expected resource constraints. The Draft Institutional Plan is the product of many discussions between DOE and Argonne program managers, and it also reflects programmatic priorities developed during Argonne's summer strategic planning process. That process serves additionally to identify new areas of strategic value to DOE and Argonne, to which Laboratory Directed Research and Development funds may be applied. The Draft Plan is provided to the Department before Argonne's On-Site Review. Issuance of the final Institutional Plan in the fall, after further comment and discussion, marks the culmination of the Laboratory's annual planning cycle. Chapter II of this Institutional Plan describes Argonne's missions and roles within the DOE laboratory system, its underlying core competencies in science and technology, and six broad planning objectives whose achievement is considered critical to the future of the Laboratory. Chapter III presents the Laboratory's ''Science and Technology Strategic Plan,'' which summarizes key features of the external environment, presents Argonne's vision, and describes how Argonne's strategic goals and objectives support DOE's four business lines. The balance of Chapter III comprises strategic plans for 23 areas of science and technology at Argonne, grouped according to the four DOE business lines. The Laboratory's 14 major initiatives, presented in Chapter IV, propose important advances in key areas of fundamental science and technology development. The ''Operations and Infrastructure Strategic Plan'' in Chapter V includes strategic plans for human resources; environmental protection, safety, and health; site and

  19. Establishing a national biological laboratory safety and security monitoring program.

    PubMed

    Blaine, James W

    2012-12-01

    The growing concern over the potential use of biological agents as weapons and the continuing work of the Biological Weapons Convention has promoted an interest in establishing national biological laboratory biosafety and biosecurity monitoring programs. The challenges and issues that should be considered by governments, or organizations, embarking on the creation of a biological laboratory biosafety and biosecurity monitoring program are discussed in this article. The discussion focuses on the following questions: Is there critical infrastructure support available? What should be the program focus? Who should be monitored? Who should do the monitoring? How extensive should the monitoring be? What standards and requirements should be used? What are the consequences if a laboratory does not meet the requirements or is not willing to comply? Would the program achieve the results intended? What are the program costs? The success of a monitoring program can depend on how the government, or organization, responds to these questions.

  20. Gran Sasso National Laboratory: Outreach and communication activities

    NASA Astrophysics Data System (ADS)

    Antolini, R.; Di Giovanni, A.; Galeota, M.; Sebastiani, S.

    2010-01-01

    Due to its fascinating structures, the Gran Sasso National Laboratory (LNGS) offers huge opportunities for communication and outreach activities conceived for students and general public. A great effort is devoted to the organisation of the "OPEN DAY", in which the scientific staff of Gran Sasso introduces non expert people to the main relevant research topics of the laboratory through interactive demonstrations and particle detectors. In particular, a portable cosmic rays telescope has been realized: the detector is used by LNGS team in pubblic events as well as to promote the scientific activities of the Laboratory. In order to point out the importance of the scientific culture for young people, LNGS is involved in the organisation of several training courses for students and teachers focused on the improvement of the knowledge on modern physics topics. Since May 2008 is operating in Teramo the "Galileium", an interactive museum for physics and astrophysics.

  1. Annotated bibliography National Environmental Policy Act (NEPA) documents for Sandia National Laboratories

    SciTech Connect

    Harris, J.M.

    1995-04-01

    The following annotated bibliography lists documents prepared by the Department of Energy (DOE), and predecessor agencies, to meet the requirements of the National Environmental Policy Act (NEPA) for activities and facilities at Sandia National Laboratories sites. For each NEPA document summary information and a brief discussion of content is provided. This information may be used to reduce the amount of time or cost associated with NEPA compliance for future Sandia National Laboratories projects. This summary may be used to identify model documents, documents to use as sources of information, or documents from which to tier additional NEPA documents.

  2. The OIE World Animal Health Information System: the role of OIE Reference Laboratories and Collaborating Centres in disease reporting.

    PubMed

    Ben Jebara, K

    2010-12-01

    One of the main objectives of the World Organisation for Animal Health (OIE) is to ensure transparency in and knowledge of the world animal health situation. To achieve this objective, the OIE relies on its network of Member Countries, which is complemented by the activities of 221 Reference Laboratories (RLs) and Collaborating Centres. The RL mandate states that, in the case of positive results for diseases notifiable to the OIE, the laboratory should inform the OIE Delegate of the Member Country from which the samples originated and send a copy of the information to OIE Headquarters. However, since 2006 the OIE has received a lower than expected number of notifications from RLs, which implies eitherthat the majority of samples are sent to national laboratories or that some RLs are not fully complying with their mandate. The OIE sent a questionnaire to RLs in preparation for the Second Global Conference of OIE Reference Laboratories and Collaborating Centres (Paris, France, 21-23 June 2010). Two main factors emerged: the need for RLs to clarify their role and responsibilities in disease reporting and the need for an awareness campaign to sensitise national Veterinary Services to the importance of conducting more surveillance (and consequently of submitting samples to RLs) for all OIE-listed diseases. Reference laboratories indicated two main reasons for not sharing more data on positive samples with the OIE: i) a perceived contradiction between their mandate as OIE RLs and the standards of the International Organization for Standardization (ISO) dealing with confidentiality; and ii) certain Member Countries or stakeholders asking RLs not to share positive results with the OIE, for political or economic reasons. The OIE has put forward proposals to help RLs resolve these problems in future. The use of ISO standards must be clarified and there must be improved communication between the OIE and its RLs. A lack of transparency about a significant disease event can

  3. Sandia National Laboratories, California Waste Management Program annual report.

    SciTech Connect

    Brynildson, Mark E.

    2010-02-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Waste Management Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. This annual program report describes the activities undertaken during the past year, and activities planned in future years to implement the Waste Management (WM) Program, one of six programs that supports environmental management at SNL/CA.

  4. Oak Ridge National Laboratory Review. Volume 25, No. 1, 1992

    SciTech Connect

    Krause, C.; Pearce, J.; Zucker, A.

    1992-10-01

    This report presents brief descriptions of the following programs at Oak Ridge National Laboratory: The effects of pollution and climate change on forests; automation to improve the safety and efficiency of rearming battle tanks; new technologies for DNA sequencing; ORNL probes the human genome; ORNL as a supercomputer research center; paving the way to superconcrete made with polystyrene; a new look at supercritical water used in waste treatment; and small mammals as environmental monitors.

  5. Equipment qualification testing evaluation experiences at Sandia National Laboratories

    SciTech Connect

    Bustard, L.D.; Wyant, F.J.; Bonzon, L.L.; Gillen, K.T.

    1986-01-01

    The USNRC has sponsored a number of programs at Sandia National Laboratories specifically addressing safety-related equipment qualification. The most visible of these programs has been the Qualification Testing Evaluation (QTE) program. Other relevant programs have included the Equipment Qualification Methodology Research Test program (CAP). Over a ten year period these programs have collectively tested numerous types of safety-related equipment. Some insights and conclusions extracted from these testing experiences are summarized in this report.

  6. Idaho National Laboratory (INL) Sitewide Institutional Controls Plan

    SciTech Connect

    W. L. Jolley

    2006-07-27

    On November 9, 2002, the U.S. Environmental Protection Agency (EPA), the U.S. Department of Energy (DOE), and the Idaho Department of Environmental Quality approved the Record of Decision Experimental Breeder Reactor-I/Boiling Water Reactor Experiment Area and Miscellaneous Sites, which requires a Sitewide Institutional Controls Plan for the then Idaho National Engineering and Environmental Laboratory (now known as the Idaho National Laboratory). This document, first issued in June 2004, fulfilled that requirement. The revision is needed to provide an update as remedial actions are completed and new areas of concern are found. This Sitewide Institutional Controls Plan is based on guidance in the May 3, 1999, EPA Region 10 Final Policy on the Use of Institutional Controls at Federal Facilities; the September 29, 2000, EPA guidance Institutional Controls: A Site Manager's Guide to Identifying, Evaluating, and Selecting Institutional Controls at Superfund and RCRA Corrective Action Cleanups; and the April 9, 2003, DOE Policy 454.1, "Use of Institutional Controls." These policies establish measures that ensure short- and long-term effectiveness of institutional controls that protect human health and the environment at federal facility sites undergoing remedial action pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) and/or corrective action pursuant to the Resource Conservation and Recovery Act (RCRA). The site-specific institutional controls currently in place at the Idaho National Laboratory are documented in this Sitewide Institutional Controls Plan. This plan is being updated, along with the Idaho National Engineering and Environmental Laboratory Comprehensive Facilities and Land Use Plan, to reflect the progress of remedial activities and changes in CERCLA sites.

  7. Idaho National Laboratory FY12 Greenhouse Gas Report

    SciTech Connect

    Kimberly Frerichs

    2013-03-01

    A greenhouse gas (GHG) inventory is a systematic approach to account for the production and release of certain gases generated by an institution from various emission sources. The gases of interest are those that climate science has identified as related to anthropogenic global climate change. This document presents an inventory of GHGs generated during Fiscal Year (FY) 2012 by Idaho National Laboratory (INL), a Department of Energy (DOE) sponsored entity, located in southeastern Idaho.

  8. Idaho National Laboratory's FY11 Greenhouse Gas Report

    SciTech Connect

    Kimberly Frerichs

    2012-03-01

    A greenhouse gas (GHG) inventory is a systematic approach to account for the production and release of certain gases generated by an institution from various emission sources. The gases of interest are those that climate science has identified as related to anthropogenic global climate change. This document presents an inventory of GHGs generated during Fiscal Year (FY) 2011 by Idaho National Laboratory (INL), a Department of Energy (DOE)-sponsored entity, located in southeastern Idaho.

  9. Monolithic circuit development for RHIC at Oak Ridge National Laboratory

    SciTech Connect

    Alley, G.T.; Britton, C.L. Jr.; Kennedy, E.J.; Newport, D.F.; Wintenberg, A.L.; Young, G.R.

    1991-12-31

    The work performed for RHIC at Oak Ridge National Laboratory during FY 91 is presented in this paper. The work includes preamplifier, analog memory, and analog-digital converter development for Dimuon Pad Readout, and evaluation and development of preamplifier-shapers for silicon strip readout. The approaches for implementation are considered as well as measured data for the various circuits that have been developed.

  10. Strategic defense initiatives at Los Alamos National Laboratory

    SciTech Connect

    Rockwood, S.D.

    1985-01-01

    This presentation reviews the Strategic Defense Initiative (SDI) programs at Los Alamos National Laboratory, noting especially the needs for and applications of optics and optical technologies. Table I lists the various activities at Los Alamos contributing to SDI programs. The principal, nonnuclear SDI programs are: (1) the free-electron laser, and (2) neutral particle beams. Both should be considered as potential long-range-kill systems, but still in the futuristic category.

  11. Inertial Confinement Fusion Research at LOS Alamos National Laboratory

    NASA Astrophysics Data System (ADS)

    Batha, S. H.; Albright, B. J.; Alexander, D. J.; Barnes, Cris W.; Bradley, P. A.; Cobble, J. A.; Cooley, J. C.; Cooley, J. H.; Day, R. D.; DeFriend, K. A.; Delamater, N. D.; Dodd, E. S.; Fatherley, V. E.; Fernandez, J. C.; Flippo, K. A.; Grim, G. P.; Goldman, S. R.; Greenfield, S. R.; Herrmann, H. W.; Hoffman, N. M.; Holmes, R. L.; Johnson, R. P.; Keiter, P. A.; Kline, J. L.; Kyrala, G. A.; Lanier, N. E.; Loomis, E.; Lopez, F. E.; Luo, S.; Mack, J. M.; Magelssen, G. R.; Montgomery, D. S.; Nobile, A.; Oertel, J. A.; Reardon, P.; Rose, H. A.; Schmidt, D.; Schmitt, M. J.; Seifter, A.; Shimada, T.; Swift, D. C.; Tierney, T. E.; Welser-Sherrill, L.; Wilke, M. D.; Wilson, D. C.; Workman, J.; Yin, L.

    2009-07-01

    Inertial confinement fusion research at Los Alamos National Laboratory is focused on high-leverage areas of thermonuclear ignition to which LANL can apply its historic strengths and that are complementary to high-energy-density-physics topics. Using the Trident and Omega laser facilities, experiments are pursued in laser-plasma instabilities, symmetry, Be technologies, neutron and fusion-product diagnostics, and defect hydrodynamics.

  12. Application of optical interconnect technology at Lawrence Livermore National Laboratory

    SciTech Connect

    Haigh, R.E.; Lowry, M.E.; McCammon, K.; Hills, R.; Mitchell, R.; Sweider, D.

    1995-08-10

    Optical interconnects will be required to meet the information bandwidth requirements of future communication and computing applications. At Lawrence Livermore National Laboratory, the authors are involved in applying optical interconnect technologies in two distinct application areas: Multi-Gigabit/sec Computer Backplanes and Gigabit/sec Wide Area Networking using Wavelength Division Multiplexing. In this paper, the authors discuss their efforts to integrate optical interconnect technologies into prototype computing and communication systems.

  13. Los Alamos National Laboratory's high-performance data system

    SciTech Connect

    Mercier, C.; Chorn, G.; Christman, R.; Collins, B.

    1991-01-01

    Los Alamos National Laboratory is designing a High-Performance Data System (HPDS) that will provide storage for supercomputers requiring large files and fast transfer speeds. The HPDS will meet the performance requirements by managing data transfers from high-speed storage systems connected directly to a high-speed network. File and storage management software will be distributed in workstations. Network protocols will ensure reliable, wide-area network data delivery to support long-distance distributed processing. 3 refs., 2 figs.

  14. Implementing a lessons learned process at Sandia National Laboratories

    SciTech Connect

    Fosshage, Erik D.; Drewien, Celeste A.; Eras, Kenneth; Hartwig, Ronald Craig; Post, Debra S.; Stoecker, Nora Kathleen

    2016-01-01

    The Lessons Learned Process Improvement Team was tasked to gain an understanding of the existing lessons learned environment within the major programs at Sandia National Laboratories, identify opportunities for improvement in that environment as compared to desired attributes, propose alternative implementations to address existing inefficiencies, perform qualitative evaluations of alternative implementations, and recommend one or more near-term activities for prototyping and/or implementation. This report documents the work and findings of the team.

  15. Astronomy Applications of Adaptive Optics at Lawrence Livermore National Laboratory

    SciTech Connect

    Bauman, B J; Gavel, D T

    2003-04-23

    Astronomical applications of adaptive optics at Lawrence Livermore National Laboratory (LLNL) has a history that extends from 1984. The program started with the Lick Observatory Adaptive Optics system and has progressed through the years to lever-larger telescopes: Keck, and now the proposed CELT (California Extremely Large Telescope) 30m telescope. LLNL AO continues to be at the forefront of AO development and science.

  16. Sandia National Laboratories, California Hazardous Materials Management Program annual report.

    SciTech Connect

    Brynildson, Mark E.

    2011-02-01

    The annual program report provides detailed information about all aspects of the Sandia National Laboratories, California (SNL/CA) Hazardous Materials Management Program. It functions as supporting documentation to the SNL/CA Environmental Management System Program Manual. This program annual report describes the activities undertaken during the calender past year, and activities planned in future years to implement the Hazardous Materials Management Program, one of six programs that supports environmental management at SNL/CA.

  17. Highlighting High Performance Buildings: National Renewable Energy Laboratory's Visitors Center

    SciTech Connect

    2001-06-01

    The National Renewable Energy Laboratory Visitors Center, also known as the Dan Schaefer Federal Building, is a high-performance building located in Golden, Colorado. The 6,400-square-foot building incorporates passive solar heating, energy-efficient lighting, an evaporative cooling system, and other technologies to minimize energy costs and environmental impact. The Visitors Center displays a variety of interactive exhibits on energy efficiency and renewable energy, and the building includes an auditorium, a public reading room, and office space.

  18. Customer Satisfaction Assessment at the Pacific Northwest National Laboratory

    SciTech Connect

    Anderson, Dale N.; Sours, Mardell L.

    2000-03-20

    The Pacific Northwest National Laboratory (PNNL) is developing and implementing a customer satisfaction assessment program (CSAP) to assess the quality of research and development provided by the laboratory. We present the customer survey component of the PNNL CSAP. The customer survey questionnaire is composed of 2 major sections, Strategic Value and Project Performance. The Strategic Value section of the questionnaire consists of 5 questions that can be answered with a 5 point Likert scale response. These questions are designed to determine if a project is directly contributing to critical future national needs. The Project Performance section of the questionnaire consists of 9 questions that can be answered with a 5 point Likert scale response. These questions determine PNNL performance in meeting customer expectations. Many approaches could be used to analyze customer survey data. We present a statistical model that can accurately capture the random behavior of customer survey data. The properties of this statistical model can be used to establish a "gold standard'' or performance expectation for the laboratory, and then assess progress. The gold standard is defined from input from laboratory management --- answers to 4 simple questions, in terms of the information obtained from the CSAP customer survey, define the standard: *What should the average Strategic Value be for the laboratory project portfolio? *What Strategic Value interval should include most of the projects in the laboratory portfolio? *What should average Project Performance be for projects with a Strategic Value of about 2? *What should average Project Performance be for projects with a Strategic Value of about 4? We discuss how to analyze CSAP customer survey data with this model. Our discussion will include "lessons learned" and issues that can invalidate this type of assessment.

  19. Microscale chemistry technology exchange at Argonne National Laboratory - east.

    SciTech Connect

    Pausma, R.

    1998-06-04

    The Division of Educational Programs (DEP) at Argonne National Laboratory-East interacts with the education community at all levels to improve science and mathematics education and to provide resources to instructors of science and mathematics. DEP conducts a wide range of educational programs and has established an enormous audience of teachers, both in the Chicago area and nationally. DEP has brought microscale chemistry to the attention of this huge audience. This effort has been supported by the U.S. Department of Energy through the Environmental Management Operations organization within Argonne. Microscale chemistry is a teaching methodology wherein laboratory chemistry training is provided to students while utilizing very small amounts of reagents and correspondingly small apparatus. The techniques enable a school to reduce significantly the cost of reagents, the cost of waste disposal and the dangers associated with the manipulation of chemicals. The cost reductions are achieved while still providing the students with the hands-on laboratory experience that is vital to students who might choose to pursue careers in the sciences. Many universities and colleges have already begun to switch from macroscale to microscale chemistry in their educational laboratories. The introduction of these techniques at the secondary education level will lead to freshman being better prepared for the type of experimentation that they will encounter in college.

  20. Oak Ridge National Laboratory institutional plan, FY 1990--FY 1995

    SciTech Connect

    Not Available

    1989-11-01

    The Oak Ridge National Laboratory is one of DOE's major multiprogram energy laboratories. ORNL's program missions are (1) to conduct applied research and engineering development in support of DOE's programs in fusion, fission, fossil, renewables (biomass), and other energy technologies, and in the more efficient conversion and use of energy (conservation) and (2) to perform basic scientific research in selected areas of the physical and life sciences. These missions are to be carried out in compliance with environmental, safety, and health regulations. Transfer of science and technology is an integral component of our missions. A complementary mission is to apply the Laboratory's resources to other nationally important tasks when such work is synergistic with the program missions. Some of the issues addressed include education, international competitiveness, hazardous waste research and development, and selected defense technologies. In addition to the R D missions, ORNL performs important service roles for DOE; these roles include designing, building, and operating user facilities for the benefit of university and industrial researchers and supplying radioactive and stable isotopes that are not available from private industry. Scientific and technical efforts in support of the Laboratory's missions cover a spectrum of activities. In fusion, the emphasis is on advanced studies of toroidal confinement, plasma heating, fueling systems, superconducting magnets, first-wall and blanket materials, and applied plasma physics. 69 figs., 49 tabs.

  1. Universities and national laboratory roles in nuclear engineering

    NASA Astrophysics Data System (ADS)

    Sackett, J. I.

    Nuclear Engineering Education is being significantly challenged in the United States. The decline in enrollment generally and the reduction of the number of nuclear engineering departments has been well documented. These declines parallel a lack of new construction for nuclear power plants and a decline in research and development to support new plant design. Precisely at a time when innovation is needed to deal with many issues facing nuclear power, the number of qualified people to do so is being reduced. It is important that the University and National Laboratory Communities cooperate to address these issues. The Universities must increasingly identify challenges facing nuclear power that demand innovative solutions and pursue them. To be drawn into the technology the best students must see a future, a need and identify challenges that they can meet. The University community can provide that vision with help from the National Laboratories. It has been a major goal within the reactor development program at Argonne National Laboratory to establish the kind of program that can help accomplish this.

  2. Partnership Opportunities with the Oak Ridge National Laboratory

    SciTech Connect

    Kniel, C.; Payne, T.L.

    1999-11-14

    As a U.S. Department of Energy (DOE) Office of Science (SC) National Laboratory, the Oak Ridge National Lab (ORNL) participates in the Laboratory Technology Research (LTR) Program. The mission of the LTR Program is to advance science and technology, in support of DOE missions, toward innovative applications through cost-shared partnerships with the private sector. The benefits to industry participants include gaining access to world-class researchers and facilities, while the benefits to the ORNL researchers includes leveraging the declining government-provided funds. Thus, the importance placed upon industry partner satisfaction is large, especially if the LTR Program is to be sustained during episodes of government budget constraints. Realizing the critical nature of partner satisfaction, in 1998 the DOE-SC National Laboratories surveyed industrial partners to assess their satisfaction with the cooperative research projects in which they were involved. This paper will describe the survey methodology including development of the questionnaire and a summary of the responses (particularly those which are germane to the ORNL.) The results of the survey will be categorized as follows: (1) Desire to partner again with ORNL; (2) Benefits obtained by the company from the partnership; and (3) LTR Program ratings assigned in 11 key areas (i.e., quality of work, expertise, protection of intellectual property, value, facilities, understanding company needs, reliability of funding, schedule responsiveness, project management, contract negotiation, and contract administration.)

  3. Idaho National Laboratory Site Long-Term Stewardship Implementation Plan

    SciTech Connect

    B. E. Olaveson

    2006-07-27

    The U.S. Department of Energy has established long-term stewardship programs to protect human health and the environment at sites where residual contamination remains after site cleanup. At the Idaho National Laboratory Site, Comprehensive Environmental Response, Compensation, and Liability Act (CERLA) long-term stewardship activities performed under the aegis of regulatory agreements, the Federal Facility Agreement and Consent Order for the Idaho National Laboratory, and state and federal requirements are administered primarily under the direction of the Idaho Cleanup Project. It represents a subset of all on-going environmental activity at the Idaho National Laboratory Site. This plan provides a listing of applicable CERCLA long-term stewardship requirements and their planned and completed implementation goals. It proffers the Long-Term Stewardship Environmental Data Warehouse for Sitewide management of environmental data. This plan will be updated as needed over time, based on input from the U.S. Department of Energy, its cognizant subcontractors, and other local and regional stakeholders.

  4. Technology Innovation for the CTBT, the National Laboratory Contribution

    NASA Astrophysics Data System (ADS)

    Goldstein, W. H.

    2016-12-01

    The Comprehensive Nuclear-Test-Ban Treaty (CTBT) and its Protocol are the result of a long history of scientific engagement and international technical collaboration. The U.S. Department of Energy National Laboratories have been conducting nuclear explosive test-ban research for over 50 years and have made significant contributions to this legacy. Recent examples include the RSTT (regional seismic travel time) computer code and the Smart Sampler—both of these products are the result of collaborations among Livermore, Sandia, Los Alamos, and Pacific Northwest National Laboratories. The RSTT code enables fast and accurate seismic event locations using regional data. This code solves the long-standing problem of using teleseismic and regional seismic data together to locate events. The Smart Sampler is designed for use in On-site Inspections to sample soil gases to look for noble gas fission products from a potential underground nuclear explosive test. The Smart Sampler solves the long-standing problem of collecting soil gases without contaminating the sample with gases from the atmosphere by operating only during atmospheric low-pressure events. Both these products are being evaluated by the Preparatory Commission for the CTBT Organization and the international community. In addition to R&D, the National Laboratories provide experts to support U.S. policy makers in ongoing discussions such as CTBT Working Group B, which sets policy for the development of the CTBT monitoring and verification regime.

  5. Environmental Survey preliminary report, Argonne National Laboratory, Argonne, Illinois

    SciTech Connect

    Not Available

    1988-11-01

    This report presents the preliminary findings of the first phase of the Environmental Survey of the United States Department of Energy's (DOE) Argonne National Laboratory (ANL), conducted June 15 through 26, 1987. The Survey is being conducted by an interdisciplinary team of environmental specialists, led and managed by the Office of Environment, Safety and Health's Office of Environmental Audit. The team includes outside experts supplied by a private contractor. The objective of the Survey is to identify environmental problems and areas of environmental risk associated with ANL. The Survey covers all environmental media and all areas of environmental regulation. It is being performed in accordance with the DOE Environmental Survey Manual. The on-site phase of the Survey involves the review of existing site environmental data, observations of the operations carried on at ANL, and interviews with site personnel. The Survey team developed a Sampling and Analysis (S A) Plan to assist in further assessing certain of the environmental problems identified during its on-site activities. The S A Plan will be executed by the Oak Ridge National Laboratory (ORNL). When completed, the S A results will be incorporated into the Argonne National Laboratory Environmental Survey findings for inclusion in the Environmental Survey Summary Report. 75 refs., 24 figs., 60 tabs.

  6. Post Irradiation Capabilities at the Idaho National Laboratory

    SciTech Connect

    Schulthess, J.L.; Robert D. Mariani; Rory Kennedy; Doug Toomer

    2011-08-01

    The U.S. Department of Energy (DOE) Office of Nuclear Energy (NE) oversees the research, development, and demonstration activities that ensure nuclear energy remains a viable energy option for the United States. Fuel and material development through fabrication, irradiation, and characterization play a significant role in accomplishing the research needed to support nuclear energy. All fuel and material development requires the understanding of irradiation effects on the fuel performance and relies on irradiation experiments ranging from tests aimed at targeted scientific questions to integral effects under representative and prototypic conditions. The DOE recently emphasized a solution-driven, goal-oriented, science-based approach to nuclear energy development. Nuclear power systems and materials were initially developed during the latter half of the 20th century and greatly facilitated by the United States’ ability and willingness to conduct large-scale experiments. Fifty-two research and test reactors with associated facilities for performing fabrication and pre and post irradiation examinations were constructed at what is now Idaho National Laboratory (INL), another 14 at Oak Ridge National Laboratory (ORNL), and a few more at other national laboratory sites. Building on the scientific advances of the last several decades, our understanding of fundamental nuclear science, improvements in computational platforms, and other tools now enable technological advancements with less reliance on large-scale experimentation.

  7. Post Irradiation Capabilities at the Idaho National Laboratory

    SciTech Connect

    Schulthess, J.L.

    2011-08-01

    The U.S. Department of Energy (DOE) Office of Nuclear Energy (NE) oversees the research, development, and demonstration activities that ensure nuclear energy remains a viable energy option for the United States. Fuel and material development through fabrication, irradiation, and characterization play a significant role in accomplishing the research needed to support nuclear energy. All fuel and material development requires the understanding of irradiation effects on the fuel performance and relies on irradiation experiments ranging from tests aimed at targeted scientific questions to integral effects under representative and prototypic conditions. The DOE recently emphasized a solution-driven, goal-oriented, science-based approach to nuclear energy development. Nuclear power systems and materials were initially developed during the latter half of the 20th century and greatly facilitated by the United States ability and willingness to conduct large-scale experiments. Fifty-two research and test reactors with associated facilities for performing fabrication and pre and post irradiation examinations were constructed at what is now Idaho National Laboratory (INL), another 14 at Oak Ridge National Laboratory (ORNL), and a few more at other national laboratory sites. Building on the scientific advances of the last several decades, our understanding of fundamental nuclear science, improvements in computational platforms, and other tools now enable technological advancements with less reliance on large-scale experimentation.

  8. Energy and Water Conservation Assessment of the Radiochemical Processing Laboratory (RPL) at Pacific Northwest National Laboratory

    SciTech Connect

    Johnson, Stephanie R.; Koehler, Theresa M.; Boyd, Brian K.

    2014-05-31

    This report summarizes the results of an energy and water conservation assessment of the Radiochemical Processing Laboratory (RPL) at Pacific Northwest National Laboratory (PNNL). The assessment was performed in October 2013 by engineers from the PNNL Building Performance Team with the support of the dedicated RPL staff and several Facilities and Operations (F&O) department engineers. The assessment was completed for the Facilities and Operations (F&O) department at PNNL in support of the requirements within Section 432 of the Energy Independence and Security Act (EISA) of 2007.

  9. Establishing a China malaria diagnosis reference laboratory network for malaria elimination.

    PubMed

    Yin, Jian-hai; Yan, He; Huang, Fang; Li, Mei; Xiao, Hui-hui; Zhou, Shui-sen; Xia, Zhi-gui

    2015-01-28

    In China, the prevalence of malaria has reduced dramatically due to the elimination programme. The continued success of the programme will depend upon the accurate diagnosis of the disease in the laboratory. The basic requirements for this are a reliable malaria diagnosis laboratory network and quality management system to support case verification and source tracking. The baseline information of provincial malaria laboratories in the China malaria diagnosis reference laboratory network was collected and analysed, and a quality-assurance activity was carried out to assess their accuracies in malaria diagnosis by microscopy using WHO standards and PCR. By the end of 2013, nineteen of 24 provincial laboratories have been included in the network. In the study, a total of 168 staff were registered and there was no bias in their age, gender, education level, and position. Generally Plasmodium species were identified with great accuracy by microscopy and PCR. However, Plasmodium ovale was likely to be misdiagnosed as Plasmodium vivax by microscopy. China has established a laboratory network for primary malaria diagnosis which will cover a larger area. Currently, Plasmodium species can be identified fairly accurately by microscopy and PCR. However, laboratory staff need additional trainings on accurate identification of P. ovale microscopically and good performance of PCR operations.

  10. [Building and implementation of management system in laboratories of the National Institute of Hygiene].

    PubMed

    Rozbicka, Beata; Brulińska-Ostrowska, Elzbieta

    2008-01-01

    The rules of good laboratory practice have always been observed in the laboratories of National Institute of Hygiene (NIH) and the reliability of the results has been carefully cared after when performing tests for clients. In 2003 the laboratories performing analyses related to food safety were designated as the national reference laboratories. This, added to the necessity of compliance with work standards and requirements of EU legislation and to the need of confirmation of competence by an independent organisation, led to a decision to seek accreditation of Polish Centre of Accreditation (PCA). The following stages of building and implementation of management system were presented: training, modifications of Institute's organisational structure, elaboration of management system's documentation, renovation and refurbishment of laboratory facilities, implementation of measuring and test equipment's supervision, internal audits and management review. The importance of earlier experiences and achievements with regard to validation of analytical methods and guarding of the quality of the results through organisation and participation in proficiency tests was highlighted. Current status of accreditation of testing procedures used in NIH laboratories that perform analyses in the field of chemistry, microbiology, radiobiology and medical diagnostic tests was presented.

  11. Pacific Northwest National Laboratory FY1996 midyear self-evaluation

    SciTech Connect

    1996-04-01

    As stated in our mission, the Laboratory is concentrated on DOE`s environmental quality mission and the scientific research required to support that mission. The Laboratory also supports the energy resources and national security missions in areas where an overlap between our core competencies and DOE`s goals exists. Our intent for fiscal year l996 is to focus our efforts on the critical outcomes necessary for us to meet DOE`s needs. Six Critical Outcomes were established and substantial progress has been made against five of those outcomes during the first half of the fiscal year. A summary of progress and key issues is provided. The Critical Outcomes are: Environmental Molecular Sciences Laboratory; Environmental Management; Scientific Excellence and Productivity; ES&H/Conduct of Operations; Leadership; and Economic Development. The Laboratory has also made a significant commitment to the implementation of a fully integrated self-assessment program. Efforts during the first half of the fiscal year have been focused on developing an approach for the overall program and implementation in selected organizations. The approach is holistic and focuses assessment on activities important to the successful completion of our critical outcomes. Progress towards full implementation of the integrated assessment program is meeting expectations in general, but significant effort still needs to be applied to obtain effective implementation across the Laboratory and to ensure integration with the business planning process.

  12. Termite-Susceptible Species of Wood for Inclusion as a Reference in Indonesian Standardized Laboratory Testing.

    PubMed

    Arinana; Tsunoda, Kunio; Herliyana, Elis N; Hadi, Yusuf S

    2012-03-28

    Standardized laboratory testing of wood and wood-based products against subterranean termites in Indonesia (SNI 01.7207-2006) (SNI) has no requirement for the inclusion of a comparative reference species of wood (reference control). This is considered a weakness of the Indonesian standard. Consequently, a study was undertaken to identify a suitable Indonesian species of community wood that could be used as a reference control. Four candidate species of community woods: Acacia mangium, Hevea brasiliensis, Paraserianthes falcataria and Pinus merkusii were selected for testing their susceptibility to feeding by Coptotermes formosanus. Two testing methods (SNI and the Japanese standard method JIS K 1571-2004) were used to compare the susceptibility of each species of wood. Included in the study was Cryptomeria japonica, the reference control specified in the Japanese standard. The results of the study indicated that P. merkusii is a suitable reference species of wood for inclusion in laboratory tests against subterranean termites, conducted in accordance with the Indonesian standard (SNI 01.7207-2006).

  13. 2016 Los Alamos National Laboratory Hazardous Waste Minimization Report

    SciTech Connect

    Salzman, Sonja L.; English, Charles Joe

    2016-12-02

    Waste minimization and pollution prevention are goals within the operating procedures of Los Alamos National Security, LLC (LANS). The US Department of Energy (DOE), inclusive of the National Nuclear Security Administration (NNSA) and the Office of Environmental Management, and LANS are required to submit an annual hazardous waste minimization report to the New Mexico Environment Department (NMED) in accordance with the Los Alamos National Laboratory (LANL or the Laboratory) Hazardous Waste Facility Permit. The report was prepared pursuant to the requirements of Section 2.9 of the LANL Hazardous Waste Facility Permit. This report describes the hazardous waste minimization program, which is a component of the overall Pollution Prevention (P2) Program, administered by the Environmental Stewardship Group (EPC-ES). This report also supports the waste minimization and P2 goals of the Associate Directorate of Environmental Management (ADEM) organizations that are responsible for implementing remediation activities and describes its programs to incorporate waste reduction practices into remediation activities and procedures. This report includes data for all waste shipped offsite from LANL during fiscal year (FY) 2016 (October 1, 2015 – September 30, 2016). LANS was active during FY2016 in waste minimization and P2 efforts. Multiple projects were funded that specifically related to reduction of hazardous waste. In FY2016, there was no hazardous, mixed-transuranic (MTRU), or mixed low-level (MLLW) remediation waste shipped offsite from the Laboratory. More non-remediation hazardous waste and MLLW was shipped offsite from the Laboratory in FY2016 compared to FY2015. Non-remediation MTRU waste was not shipped offsite during FY2016. These accomplishments and analysis of the waste streams are discussed in much more detail within this report.

  14. 36 CFR 1501.1 - Cross reference to National Park Service regulations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Cross reference to National Park Service regulations. 1501.1 Section 1501.1 Parks, Forests, and Public Property OKLAHOMA CITY NATIONAL MEMORIAL TRUST GENERAL PROVISIONS § 1501.1 Cross reference to National Park Service regulations...

  15. 36 CFR 1501.1 - Cross reference to National Park Service regulations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 36 Parks, Forests, and Public Property 3 2011-07-01 2011-07-01 false Cross reference to National Park Service regulations. 1501.1 Section 1501.1 Parks, Forests, and Public Property OKLAHOMA CITY NATIONAL MEMORIAL TRUST GENERAL PROVISIONS § 1501.1 Cross reference to National Park Service regulations...

  16. 36 CFR § 1501.1 - Cross reference to National Park Service regulations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 36 Parks, Forests, and Public Property 3 2013-07-01 2012-07-01 true Cross reference to National Park Service regulations. § 1501.1 Section § 1501.1 Parks, Forests, and Public Property OKLAHOMA CITY NATIONAL MEMORIAL TRUST GENERAL PROVISIONS § 1501.1 Cross reference to National Park Service regulations...

  17. An analysis of reference laboratory (send out) testing: an 8-year experience in a large academic medical center.

    PubMed

    MacMillan, Donna; Lewandrowski, Elizabeth; Lewandrowski, Kent

    2004-01-01

    Utilization of outside reference laboratories for selected laboratory testing is common in the United States. However, relatively little data exist in the literature describing the scope and impact of these services. In this study, we reviewed use of reference laboratory testing at the Massachusetts General Hospital, a large urban academic medical center in Boston, Massachusetts. A retrospective review of hospital and laboratory administrative records over an 8-year period from fiscal years (FY) 1995-2002. Over the 8 years studied, reference laboratory expenses increased 4.2-fold and totaled 12.4% of the total laboratory budget in FY 2002. Total reference laboratory test volume increased 4-fold to 68,328 tests in FY 2002 but represented only 1.06% of the total test volume in the hospital. The menu of reference laboratory tests comprised 946 tests (65.7% of the hospital test menu) compared to 494 (34.3%) of tests performed in house. The average unit cost of reference laboratory tests was essentially unchanged but was approximately 13 times greater than the average unit cost in the hospital laboratory. Much of the growth in reference laboratory cost can be attributed to the addition of new molecular, genetic, and microbiological assays. Four of the top 10 tests with the highest total cost in 2002 were molecular diagnostic tests that were recently added to the test menu. Reference laboratory testing comprises a major component of hospital clinical laboratory services. Although send out tests represent a small percentage of the total test volume, these services account for the majority of the hospital laboratory test menu and a disproportionate percentage of laboratory costs.

  18. Perspectives on Inclusive Education with Reference to United Nations

    ERIC Educational Resources Information Center

    Sharma, Arvind

    2015-01-01

    This essay explores inclusive education and explains the role of United Nations for imparting it to different nations. Undoubtedly, the UN and the United Nations Children's Fund (UNICEF) strive for all children to have equitable access to education as a basic human right. The Convention on the Rights of the Child (CRC) combined with the Convention…

  19. Low Energy Accelerator Laboratory Technical Area 53, Los Alamos National Laboratory. Environmental assessment

    SciTech Connect

    1995-04-01

    This Environmental Assessment (EA) analyzes the potential environmental impacts that would be expected to occur if the Department of Energy (DOE) were to construct and operate a small research and development laboratory building at Technical Area (TA) 53 at the Los Alamos National Laboratory (LANL), Los Alamos, New Mexico. DOE proposes to construct a small building to be called the Low Energy Accelerator Laboratory (LEAL), at a previously cleared, bladed, and leveled quarter-acre site next to other facilities housing linear accelerator research activities at TA-53. Operations proposed for LEAL would consist of bench-scale research, development, and testing of the initial section of linear particle accelerators. This initial section consists of various components that are collectively called an injector system. The anticipated life span of the proposed development program would be about 15 years.

  20. Radiological characterization plan for the Tritium Research Laboratory, Sandia National Laboratories/California

    SciTech Connect

    Garcia, T.

    1995-05-01

    In this Radiological Characterization Plan (RCP), the Health Protection Department, 8641 of Sandia National Laboratories/California provides specific information for an assessment of the radiological conditions of Building 968, the Tritium Research Laboratory (TRL), and the TRL Complex area. This RCP provides historical background information on each laboratory within the TRL Complex as related to both radiological conditions and hazardous materials. Since this plan chronicles past and present activities and outlines future actions, a final complex status report will follow the completion of this document. The Health Protection Department, 8641 anticipates that the TRL Complex will ultimately undergo a termination survey; however, this RCP does not include environmental surveys such as soil, vegetation, or ground water. The RCP does provide the basis for a final termination survey plan, when appropriate.

  1. The Lawrence Livermore National Laboratory (LLNL) multi-user Tandem Laboratory

    SciTech Connect

    Davis, J.C.

    1988-09-01

    An FN tandem laboratory, cofounded by several Lawrence Livermore National Laboratory Divisions, Sandia Livermore, and the University of California Regents, is now operational at Livermore. The accelerator, formerly the University of Washington injector, has been upgraded with SF/sub 6/, Dowlish tubes, and a NEC pelletron charging system. A conventional duoplasmatron, a tritium source, and two Cs sputtering sources will be fielded on the accelerator. Pulsed beams will be available from two source positions. The laboratory has been designed to accommodate up to 19 experimental positions with excellent optics and working vacuum. The facility is unshielded with both accelerator and radiological systems under the control of a distributed microprocessor system. Research activities at the tandem include nuclear physics and astrophysics, materials science and characterization programs, and accelerator mass spectrometry for archaeology, biomedical, environmental and geoscience investigators. 3 refs., 1 fig.

  2. Capacity building in national influenza laboratories--use of laboratory assessments to drive progress.

    PubMed

    Johnson, Lucinda E A; Muir-Paulik, Sarah A; Kennedy, Pam; Lindstrom, Steven; Balish, Amanda; Aden, Tricia; Moen, Ann C

    2015-11-06

    Laboratory testing is a fundamental component of influenza surveillance for detecting novel strains with pandemic potential and informing biannual vaccine strain selection. The United States (U.S.) Centers for Disease Control and Prevention (CDC), under the auspices of its WHO Collaborating Center for Influenza, is one of the major public health agencies which provides support globally to build national capacity for influenza surveillance. Our main objective was to determine if laboratory assessments supported capacity building efforts for improved global influenza surveillance. In 2010, 35 national influenza laboratories were assessed in 34 countries, using a standardized tool. Post-assessment, each laboratory received a report with a list of recommendations for improvement. Uptake of recommendations were reviewed 3.2 mean years after the initial assessments and categorized as complete, in-progress, no action or no update. This was a retrospective study; follow-up took place through routine project management rather than at a set time-point post-assessment. WHO data on National Influenza Centre (NIC) designation, External Quality Assessment Project (EQAP) participation and FluNet reporting was used to measure laboratory capacity longitudinally and independently of the assessments. All data was further stratified by World Bank country income category. At follow-up, 81% of 614 recommendations were either complete (350) or in-progress (145) for 32 laboratories (91% response rate). The number of countries reporting to FluNet and the number of specimens they reported annually increased between 2005, when they were first funded by CDC, and 2010, the assessment year (p < 0.01). Improvements were also seen in EQAP participation and NIC designation over time and more so for low and lower-middle income countries. Assessments using a standardized tool have been beneficial to improving laboratory-based influenza surveillance. Specific recommendations helped countries identify

  3. 2013 Los Alamos National Laboratory Hazardous Waste Minimization Report

    SciTech Connect

    Salzman, Sonja L.; English, Charles J.

    2015-08-24

    Waste minimization and pollution prevention are inherent goals within the operating procedures of Los Alamos National Security, LLC (LANS). The US Department of Energy (DOE) and LANS are required to submit an annual hazardous waste minimization report to the New Mexico Environment Department (NMED) in accordance with the Los Alamos National Laboratory (LANL or the Laboratory) Hazardous Waste Facility Permit. The report was prepared pursuant to the requirements of Section 2.9 of the LANL Hazardous Waste Facility Permit. This report describes the hazardous waste minimization program (a component of the overall Waste Minimization/Pollution Prevention [WMin/PP] Program) administered by the Environmental Stewardship Group (ENV-ES). This report also supports the waste minimization and pollution prevention goals of the Environmental Programs Directorate (EP) organizations that are responsible for implementing remediation activities and describes its programs to incorporate waste reduction practices into remediation activities and procedures. LANS was very successful in fiscal year (FY) 2013 (October 1-September 30) in WMin/PP efforts. Staff funded four projects specifically related to reduction of waste with hazardous constituents, and LANS won four national awards for pollution prevention efforts from the National Nuclear Security Administration (NNSA). In FY13, there was no hazardous, mixedtransuranic (MTRU), or mixed low-level (MLLW) remediation waste generated at the Laboratory. More hazardous waste, MTRU waste, and MLLW was generated in FY13 than in FY12, and the majority of the increase was related to MTRU processing or lab cleanouts. These accomplishments and analysis of the waste streams are discussed in much more detail within this report.

  4. On-site laboratory support of Oak Ridge National Laboratory environmental restoration field activities

    SciTech Connect

    Burn, J.L.E.

    1995-07-01

    A remedial investigation/feasibility study has been undertaken at Oak Ridge National Laboratory (ORNL). Bechtel National, Inc. and partners CH2M Hill, Ogden Environmental and Energy Services, and PEER Consultants are contracted to Lockheed Martin Energy Systems, performing this work for ORNL`s Environmental Restoration (ER) Program. An on-site Close Support Laboratory (CSL) established at the ER Field Operations Facility has evolved into a laboratory where quality analytical screening results can be provided rapidly (e.g., within 24 hours of sampling). CSL capabilities include three basic areas: radiochemistry, chromatography, and wet chemistry. Radiochemical analyses include gamma spectroscopy, tritium and carbon-14 screens using liquid scintillation analysis, and gross alpha and beta counting. Cerenkov counting and crown-ether-based separation are the two rapid methods used for radiostrontium determination in water samples. By extending count times where appropriate, method detection limits can match those achieved by off-site contract laboratories. Volatile organic compounds are detected by means of gas chromatography using either headspace or purge and trap sample introduction (based on EPA 601/602). Ionic content of water samples is determined using ion chromatography and alkalinity measurement. Ion chromatography is used to quantify both anions (based on EPA 300) and cations. Wet chemistry procedures performed at the CSL include alkalinity, pH (water and soil), soil resistivity, and dissolved/suspended solids. Besides environmental samples, the CSL routinely screens health and safety and waste management samples. The cost savings of the CSL are both direct and indirect.

  5. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2011.

    SciTech Connect

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  6. Argonne National Laboratory Annual Report of Laboratory Directed Research and Development program activities FY 2010.

    SciTech Connect

    2012-04-25

    As a national laboratory Argonne concentrates on scientific and technological challenges that can only be addressed through a sustained, interdisciplinary focus at a national scale. Argonne's eight major initiatives, as enumerated in its strategic plan, are Hard X-ray Sciences, Leadership Computing, Materials and Molecular Design and Discovery, Energy Storage, Alternative Energy and Efficiency, Nuclear Energy, Biological and Environmental Systems, and National Security. The purposes of Argonne's Laboratory Directed Research and Development (LDRD) Program are to encourage the development of novel technical concepts, enhance the Laboratory's research and development (R and D) capabilities, and pursue its strategic goals. projects are selected from proposals for creative and innovative R and D studies that require advance exploration before they are considered to be sufficiently developed to obtain support through normal programmatic channels. Among the aims of the projects supported by the LDRD Program are the following: establishment of engineering proof of principle, assessment of design feasibility for prospective facilities, development of instrumentation or computational methods or systems, and discoveries in fundamental science and exploratory development.

  7. Racial/Ethnic-Specific Reference Intervals for Common Laboratory Tests: A Comparison among Asians, Blacks, Hispanics, and White.

    PubMed

    Lim, Eunjung; Miyamura, Jill; Chen, John J

    2015-09-01

    Reference intervals (RIs) for common clinical laboratory tests are usually not developed separately for different subpopulations. The aim of this study was to investigate racial/ethnic differences in RIs of common biochemical and hematological laboratory tests using the National Health and Nutrition Examination Survey (NHANES) 2011-2012 data. This current study included 3,077 participants aged 18-65 years who reported their health status as "Excellent," "Very good," or "Good," with known race/ethnicity as white, black, Hispanic, or Asian. Quantile regression analyses adjusted for sex were conducted to evaluate racial/ethnic differences in the normal ranges of 38 laboratory tests. Significant racial/ethnic differences were found in almost all laboratory tests. Compared to whites, the normal range for Asians significantly shifted to higher values in globulin and total protein and to lower values in creatinine, hematocrit, hemoglobin, mean cell hemoglobin, mean cell hemoglobin concentration, and mean platelet volume. These results indicate that racial/ethnic subpopulations have unique distributions in the labortoary tests and race/ethnicity may need to be incorporated in the development of their RIs. Establishment of racial/ethnic-specific RIs may have significant clinical and public health implication for more accurate disease diagnosis and appropriate treatment to improve quality of patient care, especially for a state with diverse racial/ethnic subpopuations such as Hawai'i.

  8. Tiger Team assessment of the Idaho National Engineering Laboratory

    SciTech Connect

    McKenzie, Barbara J.; West, Stephanie G.; Jones, Olga G.; Kerr, Dorothy A.; Bieri, Rita A.; Sanderson, Nancy L.

    1991-08-01

    The purpose of the Safety and Health (S H) Subteam assessment was to determine the effectiveness of representative safety and health programs at the Idaho National Engineering Laboratory (INEL) site. Four Technical Safety Appraisal (TSA) Teams were assembled for this purpose by the US Department of Energy (DOE), Deputy Assistant Secretary for Safety and Quality Assurance, Office of Safety Appraisals (OSA). Team No. 1 reviewed EG G Idaho, Inc. (EG G Idaho) and the Department of Energy Field Office, Idaho (ID) Fire Department. Team No. 2 reviewed Argonne National Laboratory-West (ANL-W). Team No. 3 reviewed selected contractors at the INEL; specifically, Morrison Knudsen-Ferguson of Idaho Company (MK-FIC), Protection Technology of Idaho, Inc. (PTI), Radiological and Environmental Sciences Laboratory (RESL), and Rockwell-INEL. Team No. 4 provided an Occupational Safety and Health Act (OSHA)-type compliance sitewide assessment of INEL. The S H Subteam assessment was performed concurrently with assessments conducted by Environmental and Management Subteams. Performance was appraised in the following technical areas: Organization and Administration, Quality Verification, Operations, Maintenance, Training and Certification, Auxiliary Systems, Emergency Preparedness, Technical Support, Packaging and Transportation, Nuclear Criticality Safety, Security/Safety Interface, Experimental Activities, Site/Facility Safety Review, Radiological Protection, Personnel Protection, Worker Safety and Health (OSHA) Compliance, Fire Protection, Aviation Safety, Medical Services, and Firearms Safety.

  9. Site Environmental Report for 2010 Sandia National Laboratories, California.

    SciTech Connect

    Larsen, Barbara L.

    2011-06-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a Lockheed Martin Company, manages and operates the laboratory for the Department of Energy's National Nuclear Security Administration (NNSA). The NNSA Sandia Site Office administers the contract and oversees contractor operations at the site. This Site Environmental Report for 2010 was prepared in accordance with DOE Order 231.1A (DOE 2004a). The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2010. General site and environmental program information is also included. The Site Environmental Report is divided into ten chapters. Chapter 1, the Executive Summary, highlights compliance and monitoring results obtained in 2010. Chapter 2 provides a brief introduction to SNL/CA and the existing environment found on site. Chapter 3 summarizes SNL/CA's compliance activities with the major environmental requirements applicable to site operations. Chapter 4 presents information on environmental management, performance measures, and environmental programs. Chapter 5 presents the results of monitoring and surveillance activities in 2010. Chapter 6 discusses quality assurance. Chapters 7 through 9 provide supporting information for the report and Chapter 10 is the report distribution list.

  10. Tiger Team assessment of the Idaho National Engineering Laboratory

    SciTech Connect

    Not Available

    1991-08-01

    This report documents the Tiger Team Assessment of the Idaho National Engineering Laboratory (INEL) located in Idaho Falls, Idaho. INEL is a multiprogram, laboratory site of the US Department of Energy (DOE). Overall site management is provided by the DOE Field Office, Idaho; however, the DOE Field Office, Chicago has responsibility for the Argonne National Laboratory-West facilities and operations through the Argonne Area Office. In addition, the Idaho Branch Office of the Pittsburgh Naval Reactors Office has responsibility for the Naval Reactor Facility (NRF) at the INEL. The assessment included all DOE elements having ongoing program activities at the site except for the NRF. In addition, the Safety and Health Subteam did not review the Westinghouse Idaho Nuclear Company, Inc. facilities and operations. The Tiger Team Assessment was conducted from June 17 to August 2, 1991, under the auspices of the Office of Special Projects, Office of the Assistant Secretary for Environment, Safety and Health, Headquarters, DOE. The assessment was comprehensive, encompassing environmental, safety, and health (ES H) disciplines; management; and contractor and DOE self-assessments. Compliance with applicable federal, state, and local regulations; applicable DOE Orders; best management practices; and internal INEL site requirements was assessed. In addition, an evaluation of the adequacy and effectiveness of the DOE and the site contractors management of ES H/quality assurance programs was conducted.

  11. Tiger Team assessment of the Idaho National Engineering Laboratory

    SciTech Connect

    Goldberg, Edward S.; Keating, John J.

    1991-08-01

    The Management Subteam conducted a management assessment of Environment, Safety, and Health (ES H) programs and their implementation of Idaho National Engineering Laboratory (INEL). The objectives of the assessment were to: (1) evaluate the effectiveness of existing management functions and processes in terms of ensuring environmental compliance, and the health and safety of workers and the general public; and (2) identify probable root causes for ES H findings and concerns. Organizations reviewed were DOE-Headquarters: DOE Field Offices, Chicago (CH) and Idaho (ID); Argonne Area Offices, East (AAO-E) and West (AAO-W); Radiological and Environmental Sciences Laboratory (RESL); Argonne National Laboratory (ANL); EG G Idaho, Inc. (EG G); Westinghouse Idaho Nuclear Company, Inc. (WINCO); Rockwell-INEL; MK-Ferguson of Idaho Company (MK-FIC); and Protection Technology of Idaho, Inc. (PTI). The scope of the assessment covered the following ES H management issues: policies and procedures; roles, responsibilities, and authorities; management commitment; communication; staff development, training, and certification; recruitment; compliance management; conduct of operations; emergency planning and preparedness; quality assurance; self assessment; oversight activities; and cost plus award fee processes.

  12. Site environmental report for 2009 : Sandia National Laboratories, California.

    SciTech Connect

    Larsen, Barbara L.

    2010-06-01

    Sandia National Laboratories, California (SNL/CA) is a government-owned/contractor-operated laboratory. Sandia Corporation, a Lockheed Martin Company, operates the laboratory for the Department of Energy's National Nuclear Security Administration (NNSA). The NNSA Sandia Site Office oversees operations at the site, using Sandia Corporation as a management and operating contractor. This Site Environmental Report for 2009 was prepared in accordance with DOE Order 231.1A (DOE 2004a). The report provides a summary of environmental monitoring information and compliance activities that occurred at SNL/CA during calendar year 2009. General site and environmental program information is also included. The Site Environmental Report is divided into ten chapters. Chapter 1, the Executive Summary, highlights compliance and monitoring results obtained in 2009. Chapter 2 provides a brief introduction to SNL/CA and the existing environment found on site. Chapter 3 summarizes SNL/CA's compliance activities with the major environmental requirements applicable to site operations. Chapter 4 presents information on environmental management, performance measures, and environmental programs. Chapter 5 presents the results of monitoring and surveillance activities in 2009. Chapter 6 discusses quality assurance. Chapters 7 through 9 provide supporting information for the report and Chapter 10 is the report distribution list.

  13. Overview of photonics research at Lawrence Livermore National Laboratory

    SciTech Connect

    Roeske, F.; Deri, B.; Dijaili, S.; Lee, H.; Lowry, M.; McConaghy, C.; Patterson, F.; Pocha, M.; Strand, T.

    1994-05-01

    Much of Lawrence Livermore National Laboratory`s (LLNL) expertise in photonics was acquired in the execution of the Nuclear Testing mission. As LLNL refocuses its resources into areas that have dual benefit for the nation, their photonics program is beginning to apply these unique capabilities to key national issues involving high-speed communications, while retaining the expertise to apply the technology to defense missions. Much of the exciting work being done at LLNL will have applications in photonics systems and experiments to be used in space. The authors will describe research being conducted in the following areas: high-speed, 50 ohm, phased-matched modulators and their applications to digital links; promising new research on flat-panel displays that will be full color, fast response, very thin, and have a very high resolution; all optical switches that are extremely fast, integrable and do not have the latency problems that exist with current optical switches; semiconductor optical amplifiers that are monolithically integrable, more flexible and less expensive than existing fiber amplifiers; novel, semiconductor waveguide devices; and automated packaging techniques that will lower the cost of photonics components. Much of this research can directly benefit the development of space systems where reliability, size and cost are important considerations. Additional applications in commercial communications and in military system qualifies the photonics research at LLNL as multi-use technology.

  14. International Safeguards and the Pacific Northwest National Laboratory

    SciTech Connect

    Olsen, Khris B.; Smith, Leon E.; Frazar, Sarah L.; Kurzrok, Andrew J.; Orton, Christopher R.; Schanfein, Mark J.; Sayre, Amanda M.; Jones, Rebecca L.

    2016-07-21

    Established in 1965, Pacific Northwest National Laboratory’s (PNNL) strong technical ties and shared heritage with the nearby U.S. Department of Energy Hanford Site were central to the early development of expertise in nuclear fuel cycle signatures, separations chemistry, plutonium chemistry, environmental monitoring, modeling and analysis of reactor systems, and nuclear material safeguards and security. From these Hanford origins, PNNL has grown into a multi-program science and engineering enterprise that utilizes this diversity to strengthen the international safeguards regime. Today, PNNL supports the International Atomic Energy Agency (IAEA) in its mission to provide assurances to the international community that nations do not use nuclear materials and equipment outside of peaceful uses. PNNL also serves in the IAEA’s Network of Analytical Laboratories (NWAL) by providing analysis of environmental samples gathered around the world. PNNL is involved in safeguards research and development activities in support of many U.S. Government programs such as the National Nuclear Security Administration’s (NNSA) Office of Research and Development, NNSA Office of Nonproliferation and Arms Control, and the U.S. Support Program to IAEA Safeguards. In addition to these programs, PNNL invests internal resources including safeguards-specific training opportunities for staff, and laboratory-directed research and development funding to further ideas that may grow into new capabilities. This paper and accompanying presentation highlight some of PNNL’s contributions in technology development, implementation concepts and approaches, policy, capacity building, and human capital development, in the field of international safeguards.

  15. Argonne National Laboratory annual report of Laboratory Directed Research and Development Program Activities FY 2009.

    SciTech Connect

    Office of the Director

    2010-04-09

    I am pleased to submit Argonne National Laboratory's Annual Report on its Laboratory Directed Research and Development (LDRD) activities for fiscal year 2009. Fiscal year 2009 saw a heightened focus by DOE and the nation on the need to develop new sources of energy. Argonne scientists are investigating many different sources of energy, including nuclear, solar, and biofuels, as well as ways to store, use, and transmit energy more safely, cleanly, and efficiently. DOE selected Argonne as the site for two new Energy Frontier Research Centers (EFRCs) - the Institute for Atom-Efficient Chemical Transformations and the Center for Electrical Energy Storage - and funded two other EFRCs to which Argonne is a major partner. The award of at least two of the EFRCs can be directly linked to early LDRD-funded efforts. LDRD has historically seeded important programs and facilities at the lab. Two of these facilities, the Advanced Photon Source and the Center for Nanoscale Materials, are now vital contributors to today's LDRD Program. New and enhanced capabilities, many of which relied on LDRD in their early stages, now help the laboratory pursue its evolving strategic goals. LDRD has, since its inception, been an invaluable resource for positioning the Laboratory to anticipate, and thus be prepared to contribute to, the future science and technology needs of DOE and the nation. During times of change, LDRD becomes all the more vital for facilitating the necessary adjustments while maintaining and enhancing the capabilities of our staff and facilities. Although I am new to the role of Laboratory Director, my immediate prior service as Deputy Laboratory Director for Programs afforded me continuous involvement in the LDRD program and its management. Therefore, I can attest that Argonne's program adhered closely to the requirements of DOE Order 413.2b and associated guidelines governing LDRD. Our LDRD program management continually strives to be more efficient. In addition to

  16. Oak Ridge National Laboratory Institutional Plan FY 1984-FY 1989

    SciTech Connect

    Not Available

    1983-11-01

    In this plan, Oak Ridge National Laboratory (ORNL) continues to be committed to scientific and technological research that is based on technical excellence and innovation and that provides a foundation for and a stimulus to broader and more sustained economic growth. DOE is being asked to assist in establishing a new program for Laboratory cooperation with industry, beginning with an initial focus on materials science. The current Institutional Plan thus projects growth in the materials science area as well as in other basic physical science areas and suggests a new initiative designed to extend the various technology transfer activities and to make them more effective by using ORNL as the trial Laboratory for some of these different approaches. This Institutional Plan projects a stable future for ORNL, with only modest amounts of growth in selected areas of research for the FY 1984-FY 1989 planning cycle. Summaries of the overall picture of the proposed budget and personnel levels for the current planning cycle are included. Scientific programs, laboratory resource development, and private sector interactions are discussed.

  17. Brookhaven National Laboratory 2008 Site Environment Report Volume 1

    SciTech Connect

    Brookhaven National Laboratory

    2009-10-01

    Brookhaven National Laboratory (BNL) prepares an annual Site Environmental Report (SER) in accordance with DOE Order 231.1A, Environment, Safety and Health Reporting of the U.S. Department of Energy. The report is written to inform the public, regulators, employees, and other stakeholders of the Laboratory's environmental performance during the calendar year in review. Volume I of the SER summarizes environmental data; environmental management performance; compliance with applicable DOE, federal, state, and local regulations; and performance in restoration and surveillance monitoring programs. BNL has prepared annual SERs since 1971 and has documented nearly all of its environmental history since the Laboratory's inception in 1947. Volume II of the SER, the Groundwater Status Report, also is prepared annually to report on the status of and evaluate the performance of groundwater treatment systems at the Laboratory. Volume II includes detailed technical summaries of groundwater data and its interpretation, and is intended for internal BNL users, regulators, and other technically oriented stakeholders. A brief summary of the information contained in Volume II is included in this volume in Chapter 7, Groundwater Protection. Both reports are available in print and as downloadable files on the BNL web page at http://www.bnl.gov/ewms/ser/. An electronic version on compact disc is distributed with each printed report. In addition, a summary of Volume I is prepared each year to provide a general overview of the report, and is distributed with a compact disc containing the full report.

  18. International Space Station: National Laboratory Education Concept Development Report

    NASA Technical Reports Server (NTRS)

    2006-01-01

    The International Space Station (ISS) program has brought together 16 spacefaring nations in an effort to build a permanent base for human explorers in low-Earth orbit, the first stop past Earth in humanity's path into space. The ISS is a remarkably capable spacecraft, by significant margins the largest and most complex space vehicle ever built. Planned for completion in 2010, the ISS will provide a home for laboratories equipped with a wide array of resources to develop and test the technologies needed for future generations of space exploration. The resources of the only permanent base in space clearly have the potential to find application in areas beyond the research required to enable future exploration missions. In response to Congressional direction in the 2005 National Aeronautics and Space Administration (NASA) Authorization Act, NASA has begun to examine the value of these unique capabilities to other national priorities, particularly education. In early 2006, NASA invited education experts from other Federal agencies to participate in a Task Force charged with developing concepts for using the ISS for educational purposes. Senior representatives from the education offices of the Department of Defense, Department of Education, Department of Energy, National Institutes of Health, and National Science Foundation agreed to take part in the Task Force and have graciously contributed their time and energy to produce a plan that lays out a conceptual framework for potential utilization of the ISS for educational activities sponsored by Federal agencies as well as other future users.

  19. Food adulteration analysis without laboratory prepared or determined reference food adulterant values.

    PubMed

    Kalivas, John H; Georgiou, Constantinos A; Moira, Marianna; Tsafaras, Ilias; Petrakis, Eleftherios A; Mousdis, George A

    2014-04-01

    Quantitative analysis of food adulterants is an important health and economic issue that needs to be fast and simple. Spectroscopy has significantly reduced analysis time. However, still needed are preparations of analyte calibration samples matrix matched to prediction samples which can be laborious and costly. Reported in this paper is the application of a newly developed pure component Tikhonov regularization (PCTR) process that does not require laboratory prepared or reference analysis methods, and hence, is a greener calibration method. The PCTR method requires an analyte pure component spectrum and non-analyte spectra. As a food analysis example, synchronous fluorescence spectra of extra virgin olive oil samples adulterated with sunflower oil is used. Results are shown to be better than those obtained using ridge regression with reference calibration samples. The flexibility of PCTR allows including reference samples and is generic for use with other instrumental methods and food products. Copyright © 2013 Elsevier Ltd. All rights reserved.

  20. Lawrence Livermore National Laboratory Surface Water Protection: A Watershed Approach

    SciTech Connect

    Coty, J

    2009-03-16

    This surface water protection plan (plan) provides an overview of the management efforts implemented at Lawrence Livermore National Laboratory (LLNL) that support a watershed approach to protect surface water. This plan fulfills a requirement in the Department of Energy (DOE) Order 450.1A to demonstrate a watershed approach for surface water protection that protects the environment and public health. This plan describes the use of a watershed approach within which the Laboratory's current surface water management and protections efforts have been structured and coordinated. With more than 800 million acres of land in the U.S. under federal management and stewardship, a unified approach across agencies provides enhanced resource protection and cost-effectiveness. The DOE adopted, along with other federal agencies, the Unified Federal Policy for a Watershed Approach to Federal Land and Resource Management (UFP) with a goal to protect water quality and aquatic ecosystems on federal lands. This policy intends to prevent and/or reduce water pollution from federal activities while fostering a cost-effective watershed approach to federal land and resource management. The UFP also intends to enhance the implementation of existing laws (e.g., the Clean Water Act [CWA] and National Environmental Policy Act [NEPA]) and regulations. In addition, this provides an opportunity for the federal government to serve as a model for water quality stewardship using a watershed approach for federal land and resource activities that potentially impact surface water and its uses. As a federal land manager, the Laboratory is responsible for a small but important part of those 800 million acres of land. Diverse land uses are required to support the Laboratory's mission and provide an appropriate work environment for its staff. The Laboratory comprises two sites: its main site in Livermore, California, and the Experimental Test Site (Site 300), near Tracy, California. The main site is largely