76 FR 53150 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-25

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-8103-05; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

78 FR 8581 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14936-A; LLAK944000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that an...

76 FR 53150 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-25

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-10169, AA-10170; LLAK-965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 81524 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-28

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-40206, F-40207; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 22414 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-21

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-8103-05; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

75 FR 53332 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-31

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-11144; LLAK-962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

77 FR 72383 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-9660, AA-9662; LLAK-944000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 54787 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-02

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-19148-16, F-19148-35; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

75 FR 28816 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-24

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-22588, F-22603; LLAK-962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

75 FR 69457 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-19155-08; LLAK964000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

76 FR 57759 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-16

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14908-B; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

76 FR 23834 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-28

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-11015, AA-12590; LLAK-962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

77 FR 5048 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14951-A; LLAK965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

76 FR 5395 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-31

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-12252, AA-12250, AA-12280, AA-12291, AA-12292, AA-12293; LLAK- 962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43...

77 FR 35998 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14864-A and F-14864-A2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is...

77 FR 4057 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-26

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-8103-05; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

75 FR 38537 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-19155-22; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

75 FR 65644 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-10668; LLAK-962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

76 FR 61736 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-05

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-10233, AA-11482; LLAK-965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 61737 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-05

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-22300; LLAK-965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

75 FR 80838 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-23

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-11908, AA-11915, AA-11916, AA-11917, AA-11909, AA-11913, AA-11914; LLAK-962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As...

76 FR 45604 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-29

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-9373; LLAK-965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

78 FR 64002 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-25

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14860-A; LLAK940000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that an...

75 FR 8106 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-12124; LLAK-962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that an...

78 FR 7807 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-04

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14908-A, F-14908-B; LLAK944000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

75 FR 6694 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-10

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-21905-51; LLAK964000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that an...

75 FR 26785 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-12

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-19155-9; LLAK964000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

77 FR 72383 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-10282, AA-10291, AA-10292, AA-10369; LLAK-944000-L14100000-HY0000- P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d...

76 FR 13428 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-11

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6666-B; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

75 FR 65644 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-26

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-11937, AA-11938, AA-11939, AA-11940, AA-11944, AA-11943, AA-11941, AA-11936, AA-11933, AA-11928, AA-11929, AA-11931, AA-11932; LLAK- 962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION...

76 FR 55414 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-07

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14838-A; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

76 FR 55415 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-07

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-9428, AA-9752, AA-11237, AA-9755, AA-9837, AA-10075, AA-11467; LLAK-965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As...

77 FR 33231 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14901-A; LLAK965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that an...

76 FR 14684 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-17

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-22014; LLAK-962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that the...

75 FR 53331 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-31

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-40300, F-40313; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

75 FR 80838 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-23

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-19155-07; LLAK964000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that an...

76 FR 22413 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-04-21

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6694-A; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given that an...

76 FR 75899 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-05

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-9915, AA-9916, AA-9921, AA-9936, AA-9937, AA-9965; LLAK-965000- L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43...

75 FR 9427 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-02

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-8103-63, AA-8103-65, F-21902-06, F-21903-54, F-21903-55, F-21903- 56; LLAK-96400-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY...

75 FR 13297 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-8448-A; AA-8448-B; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 16804 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-25

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-8102-05, AA-8102-08, AA-8102-10, AA-8102-25, AA-8102-28, AA-8102- 37, AA-8102-47; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for...

78 FR 53158 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-28

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14866-A, F-14866-A2; LLAK940000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

77 FR 72383 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-05

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14933-A, F-14933-A2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

78 FR 27991 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-13

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14879-A, F-14879-A2; LLAK940000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 43340 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-20

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6682-B, AA-6682-D, AA-6682-E, AA-6682-G, AA-6682-H, AA-6682-I, AA- 6682-A2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance...

77 FR 21802 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14839-A, F-14839-A2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

77 FR 24218 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-23

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14849-A, F-14849-A2; LLAK965 000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

78 FR 62656 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-22

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6648-A, AA-6648-C, AA-6648-O; LLAK944000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is...

76 FR 73657 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-29

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14862-A, F-14862-A2; LLAK965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

78 FR 65354 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-31

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6683-G, AA-6683-A2; LLAK940000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

75 FR 43199 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-23

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14837-G2, F-14837-H2, F-14837-I2; LLAK964000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d...

76 FR 43340 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-07-20

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14920-A; F-14920-A2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 34248 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-13

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14936-A, F-14936-A2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

78 FR 57411 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14885-A, F-14885-A2; LLAK940000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

77 FR 24217 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-23

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14879-A, F-14879-A2; LLAK962000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

78 FR 76174 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-16

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-9014-A, AA-9014-A2; LLAK940000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

75 FR 55344 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-09-10

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14828-L, F-14935-J, F-14877-B, F-14877-E and F-14877-F, LLAK962000- L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43...

75 FR 8105 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-02-23

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14842-I, F-14842-J, F-14842-K, F-14851-I; LLAK-964000-L14100000- HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7...

76 FR 47234 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-04

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6705-E, AA-6705-K, AA-6705-A2, LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is...

77 FR 59220 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-26

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-19525-A, F-19525-C, F-19525-A2, F-19525-B2; LLAK965000-L14100000- KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance. SUMMARY: As required by 43 CFR 2650.7(d...

75 FR 27359 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-14

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6647-B, AA-6647-C, AA-6647-A2; LLAK964000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is...

77 FR 5047 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-01

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14871-A, F-14871-A2; LLAK965000-L14100000-HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is hereby given...

76 FR 3156 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-19

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6691-F, AA-6691-I, AA-6691-A2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d), notice is...

75 FR 13296 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6679-B, AA-6679-C, AA-6679-F, AA-6679-G, AA-6679-K, AA-6679-M, AA- 6679-A2, LLAK964000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of Decision Approving Lands for Conveyance...

75 FR 21033 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-04-22

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-6670-F, AA-6670-L, AA-6670-M, AA-6670-A2; LLAK964000-L14100000- HY0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As required by 43 CFR 2650.7(d...

75 FR 30051 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-28

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [F-14989-B, F-14989-C, F-14989-E2, F-14989-G2, F-14989-K2, F-14989-L2; LLAK965000-L14100000-KC0000-P] Alaska Native Claims Selection AGENCY: Bureau of Land Management, Interior. ACTION: Notice of decision approving lands for conveyance. SUMMARY: As...

75 FR 26784 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-12

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-11973, AA-11993, AA-11968, AA-11972, AA-12018, AA-12013, AA-12014, AA-12015, AA-12016, AA-12017, AA-11984, AA-11994, AA-11995, AA-11996, AA-12003, AA-12012, AA-11967, AA-12020, AA-12021; LLAK-962000- L14100000-HY0000-P] Alaska Native Claims...

Native timber harvests in southeast Alaska.

Treesearch

G. Knapp

1992-01-01

The Alaska Native Claims Settlement Act established 13 Native corporations in southeast Alaska. There are 12 "village" corporations and 1 "regional" corporation (Sealaska Corporation). The Native corporations were entitled to select about 540,000 acres of land out of the Tongass National Forest; about 95 percent have been conveyed. This study...

75 FR 38536 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... surface and subsurface estates for certain lands to Arctic Slope Regional Corporation, pursuant to the... published four times in the Arctic Sounder. DATES: Any party claiming a property interest in the lands...

78 FR 57411 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-18

... appealable decision will be issued by the Bureau of Land Management (BLM) to Arctic Slope Regional... be published once a week for four consecutive weeks in the Arctic Sounder. DATES: Any party claiming...

76 FR 3156 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-19

... located in: Seward Meridian, Alaska T. 26 N., R. 47 W., Sec. 3, those lands formerly within mining claim... claim recordation AA- 32365. Containing approximately 155 acres. T. 27 N., R. 47 W., Sec. 34, those... e-mail at ak[email protected] , or by telecommunication device (TTD) through the Federal...

75 FR 13297 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... for 118.47 acres, located southeast of the Native village of Hughes, Alaska. Notice of the decision...: The Bureau of Land Management by phone at 907-271-5960, or by e-mail at ak[email protected]ak.blm.gov...

78 FR 54481 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-09-04

... FIRS is available 24 hours a day, 7 days a week, to leave a message or question with the BLM. The BLM... a week for four consecutive weeks in the Fairbanks Daily News-Miner. DATES: Any party claiming a... requirements of 43 CFR part 4 within the following time limits: 1. Unknown parties, parties unable to be...

Stock, Corporations, and the Native Land Claims Settlement: One of a Series of Articles on the Native Land Claims.

ERIC Educational Resources Information Center

Conn, Stephen

As one in a series of articles written by different professionals concerned with Alaska Native land claims, this article focuses on the role of village and regional corporations as established under the Alaska Native Claims Settlement Act of 1972. Designed to stimulate careful political/historical reading and discussion at an advanced secondary or…

75 FR 1801 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-13

... Arctic Slope Regional Corporation when the surface estate is conveyed to Kuukpik Corporation. Notice of the decision will also be published four times in the Arctic Sounder. DATES: The time limits for...

75 FR 13296 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-19

... decision will also be published four times in the Anchorage Daily News. DATES: The time limits for filing... State Office, 222 West Seventh Avenue, 13, Anchorage, Alaska 99513-7504. FOR FURTHER INFORMATION CONTACT...

77 FR 26038 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

... transmitted by electronic means, such as facsimile or email, will not be accepted as timely filed. Parties who... . Persons who use a Telecommunications Device for the Deaf (TDD) may call the Federal Information Relay...

76 FR 16804 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-25

... Bureau of Land Management (BLM) will issue an appealable decision to Arctic Slope Regional Corporation.... Aggregating approximately 39,679 acres. Notice of the decision will also be published four times in the Arctic...

New Tribes for New Times: One of a Series of Articles on the Native Land Claims.

ERIC Educational Resources Information Center

Martin, Guy

As one in a series of eight articles written by different professionals concerned with Alaska Native land claims, this article focuses on potential economic development of local and regional areas via Native management of funds derived from the Alaska Native Claims Settlement Act. Designed to stimulate careful political/historical reading and…

77 FR 35998 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-15

.... Notices of appeal transmitted by electronic means, such as facsimile or email, will not be accepted as... Information Relay Service (FIRS) at 1-800-877-8339 to contact the BLM during normal business hours. In...

78 FR 50442 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-08-19

... appeal transmitted by electronic means, such as facsimile or email, will not be accepted as timely filed... Device for the Deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339 to...

78 FR 76318 - Alaska Native Claims Selections

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-17

.... Notices of appeal transmitted by electronic means, such as facsimile or email, will not be accepted as... Telecommunications Device for the Deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339...

76 FR 72212 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-22

... appeal transmitted by electronic means, such as facsimile or email, will not be accepted as timely filed... Information Relay Service (FIRS) at 1-800-877-8339 to contact the BLM during normal business hours. In...

77 FR 16256 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-20

... appeal. 3. Notices of appeal transmitted by electronic means, such as facsimile or email, will not be... call the Federal Information Relay Service (FIRS) at 1-800-877-8339 to contact the BLM during normal...

77 FR 21802 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-11

... appeal transmitted by electronic means, such as facsimile or email, will not be accepted as timely filed... Information Relay Service (FIRS) at 1-800-877-8339 to contact the BLM during normal business hours. In...

78 FR 10634 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-14

..., shall be deemed to have waived their rights. Notices of appeal transmitted by electronic means, such as... Information Relay Service (FIRS) at 1-800-877-8339 to contact the BLM during normal business hours. In...

78 FR 8582 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-06

... transmitted by electronic means, such as facsimile or email, will not be accepted as timely filed. ADDRESSES... Device for the Deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339 to...

77 FR 26038 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-05-02

.... Notices of appeal transmitted by electronic means, such as facsimile or email, will not be accepted as... Information Relay Service (FIRS) at 1-800-877-8339 to contact the BLM during normal business hours. In...

76 FR 67472 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-11-01

.... Notices of appeal transmitted by electronic means, such as facsimile or email, will not be accepted as... Information Relay Service (FIRS) at 1-(800) 877-8339 to contact the BLM during normal business hours. In...

78 FR 10634 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-14

... their rights. Notices of appeal transmitted by electronic means, such as facsimile or email, will not be... Telecommunications Device for the Deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339...

77 FR 24217 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2012-04-23

... have 30 days from the date of receipt to file an appeal. 3. Notices of appeal transmitted by electronic... Telecommunications Device for the Deaf (TDD) may call the Federal Information Relay Service (FIRS) at 1-800-877-8339...

78 FR 16527 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

... electronic means, such as facsimile or email, will not be accepted as timely filed. ADDRESSES: A copy of the... call the Federal Information Relay Service (FIRS) at 1-800-877-8339 to contact the BLM during normal...

75 FR 2154 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-01-14

... approximately 47,029 acres. Notice of the decision will also be published four times in the Tundra Drums. DATES... at ak[email protected]ak.blm.gov . Persons who use a telecommunication device (TTD) may call the...

75 FR 69457 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-12

..., AA-8102-30, AA-8102-31, AA-8102-32, AA-8102-33, AA-8102-34, AA-8102-47; LLAK965000-L14100000-KC0000-P... at 907-271-5960, by e-mail at ak[email protected] , or by telecommunication device (TTD...

76 FR 65530 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-21

... 26; Secs. 33, 35, and 36. Containing 3,689 acres. T. 21 N., R. 47 W., Sec. 34. Containing 457.50.... FOR FURTHER INFORMATION CONTACT: The BLM by phone at 907-271-5960 or by e-mail at ak.blm.conveyance...

76 FR 75899 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-05

...., Tracts C, D and E; Sec. 36. Containing approximately 2,327 acres. T. 47 S., R. 60 W., Sec. 4, lots 1 to 4... phone at (907) 271-5960 or by email at ak[email protected] . Persons who use a Telecommunications...

Future Land Use Planning Alternatives for Alaska: One of a Series of Articles on the Native Land Claims.

ERIC Educational Resources Information Center

Parker, Walter B.

As one in a series of eight articles written by different professionals concerned with Alaska Native land claims, this article focuses on land use planning alternatives after December of 1976 when the configuration of Alaska lands will have been largely finalized under the Alaska Native Claims Settlement Act of 1972. While this particular booklet…

Environmental Issues in the Land Claims: One of a Series of Articles on the Native Land Claims.

ERIC Educational Resources Information Center

Martin, Guy

As one in a series of eight articles written by different professionals concerned with Alaska Native land claims, this article focuses on the debate of environmental issues prior to passage of the Alaska Land Claims Settlement Act. Designed to stimulate careful political/historical reading and discussion at an advanced secondary or adult level,…

To What Extent Do Native and Non-Native Writers Make Use of Collocations?

ERIC Educational Resources Information Center

Durrant, Philip; Schmitt, Norbert

2009-01-01

Usage-based models claim that first language learning is based on the frequency-based analysis of memorised phrases. It is not clear though, whether adult second language learning works in the same way. It has been claimed that non-native language lacks idiomatic formulas, suggesting that learners neglect phrases, focusing instead on orthographic…

75 FR 51098 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-08-18

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-11956, AA-11991, AA-11992, AA-11983, AA-11990, AA-11962, AA-11946, AA-11947, AA-11964, AA-11951, AA-11989, AA-11952, AA-11959, AA-11988, AA-11948, AA-11949, AA-11980, AA-11985, AA-11950, AA-11986, AA-11981, AA-11982, AA-12004, AA-12005; LLAK...

75 FR 38537 - Alaska Native Claims Selection

Federal Register 2010, 2011, 2012, 2013, 2014

2010-07-02

... DEPARTMENT OF THE INTERIOR Bureau of Land Management [AA-11960, AA-12011, AA-12010, AA-11963, AA-11974, AA-11999, AA-12019, AA-12000, AA-12001, AA-12002, AA-11975, AA-11998, AA-11997, AA-11976, AA-11966, AA-11965, AA-12009, AA-12007, AA-12008, AA-11955, AA-11953, AA-11954, AA-12006, AA-11945, AA...

Alaska Native Land Claims. [Textbook].

ERIC Educational Resources Information Center

Arnold, Robert D.; And Others

Written for students at the secondary level, this textbook on Alaska Native land claims includes nine chapters, eight appendices, photographs, maps, graphs, bibliography, and an index. Chapters are titled as follows: (1) Earliest Times (Alaska's first settlers, eighteenth century territories, and other claimants); (2) American Indians and Their…

Alaska Native Land Claims. Workbook to Accompany Textbook.

ERIC Educational Resources Information Center

Hays, Lydia L.

Written as a companion to the secondary textbook, "Alaska Native Land Claims", this student workbook is organized via 9 units and 39 chapters which parallel the text's organizational format. Each unit presents unit goals and has anywhere from three to five subsections or chapters. Each titled chapter (e.g., Alaska's First Settlers)…

The Act of Claiming Higher Education as Indigenous Space: American Indian/Alaska Native Examples

ERIC Educational Resources Information Center

Windchief, Sweeney; Joseph, Darold H.

2015-01-01

This paper examines the concept of claiming postsecondary education as Indigenous space using curriculum, American Indian student services, and digital media. The intention of this manuscript is to address the disparities that are the result of assimilative educational practices in higher education for American Indians and Alaska Natives by…

The Digital Natives as Learners: Technology Use Patterns and Approaches to Learning

ERIC Educational Resources Information Center

Thompson, Penny

2013-01-01

This study investigated the claims made in the popular press about the "digital native" generation as learners. Because students' lives today are saturated with digital media at a time when their brains are still developing, many popular press authors claim that this generation of students thinks and learns differently than any generation that has…

Deontic reasoning as a target of selection: reply to Astington and Dack.

PubMed

Cummins, Denise Dellarosa

2013-12-01

In their discussion of young children's deontic reasoning performance, Astington and Dack (2013) made the following claims: (1) Children need more cues to elicit cogent social norm reasoning than adults require, namely, explicit reference to authority; (2) Deontic reasoning improves with age, and this is evidence against a nativist view; (3) All evolutionary explanations of deontic reasoning advantages require positing a ''domain-specific deontic reasoning module."; and (4) young children excel at deontic reasoning because it is easier. Here, I refute each claim. Instead, I argue that (1) Social norm reasoning is one type of deontic reasoning that has been the target of selective pressure; (2) Development does not preclude nativism; (3) Epistemic utterances make no greater processing demands than deontic utterances; and (4) both adult and child norm reasoning performance is strongly influenced by reference to or implication of authority. Copyright © 2013 Elsevier Inc. All rights reserved.

Arguing about innateness.

PubMed

Valian, Virginia

2014-07-01

This paper lays out the components of a language acquisition model, the interconnections among the components, and the differing stances of nativism and empiricism about syntax. After demonstrating that parsimony cannot decide between the two stances, the paper analyzes nine examples of evidence that have been used to argue for or against nativism, concluding that most pieces of evidence are either irrelevant or suggest that language is special but need not invoke innate ideas. Two pieces of evidence - the development of home sign languages and the acquisition of Determiners - do show not just that language is special but that the child has innate syntactic content. The existential claim that nativism makes - there is at least one innate syntactic idea - is an easier claim to verify than the universal claim that empiricism makes - there are no innate syntactic ideas.

Planning How to Use Land in Village Alaska: One of a Series of Articles on the Native Land Claims.

ERIC Educational Resources Information Center

Weeden, Bob

As one in a series of eight articles written by different professionals concerned with Alaska Native land claims, this article focuses on the influence of change and competition in land use planning. Designed to stimulate careful political/historical assessment at an advanced secondary or adult level, this booklet presents a vocabulary list, 9…

Immigrants’ use of emergency primary health care in Norway: a registry-based observational study

PubMed Central

2012-01-01

Background Emigrants are often a selected sample and in good health, but migration can have deleterious effects on health. Many immigrant groups report poor health and increased use of health services, and it is often claimed that they tend to use emergency primary health care (EPHC) services for non-urgent purposes. The aim of the present study was to analyse immigrants’ use of EPHC, and to analyse variations according to country of origin, reason for immigration, and length of stay in Norway. Methods We conducted a registry based study of all immigrants to Norway, and a subsample of immigrants from Poland, Germany, Iraq and Somalia, and compared them with native Norwegians. The material comprised all electronic compensation claims for EPHC in Norway during 2008. We calculated total contact rates, contact rates for selected diagnostic groups and for services given during consultations. Adjustments for a series of socio-demographic and socio-economic variables were done by multiple logistic regression analyses. Results Immigrants as a whole had a lower contact rate than native Norwegians (23.7% versus 27.4%). Total contact rates for Polish and German immigrants (mostly work immigrants) were 11.9% and 7.0%, but for Somalis and Iraqis (mostly asylum seekers) 31.8% and 33.6%. Half of all contacts for Somalis and Iraqis were for non-specific pain, and they had relatively more of their contacts during night than other groups. Immigrants’ rates of psychiatric diagnoses were low, but increased with length of stay in Norway. Work immigrants suffered less from respiratory and gastrointestinal infections, but had more injuries and higher need for sickness certification. All immigrant groups, except Germans, were more often given a sickness certificate than native Norwegians. Use of interpreter was reduced with increasing length of stay. All immigrant groups had an increased need for long consultations, while laboratory tests were most often used for Somalis and Iraqis. Conclusions Immigrants use EPHC services less than native Norwegians, but there are large variations among immigrant groups. Work immigrants from Germany and Poland use EPHC considerably less, while asylum seekers from Somalia and Iraq use these services more than native Norwegians. PMID:22958343

Alaska Natives & the Land.

ERIC Educational Resources Information Center

Arnold, Robert D.; And Others

Pursuant to the Native land claims within Alaska, this compilation of background data and interpretive materials relevant to a fair resolution of the Alaska Native problem seeks to record data and information on the Native peoples; the land and resources of Alaska and their uses by the people in the past and present; land ownership; and future…

36 CFR 51.83 - Sale of Native Handicrafts.

Code of Federal Regulations, 2010 CFR

2010-07-01

... in the Metalakatla Indian Community), Eskimo, or Aleut blood, or combination thereof. The term... includes, in the absence of a minimum blood quantum, any citizen of the United States who is regarded as an Alaska Native by the Alaska native village or native groups of which he or she claims to be a member and...

Students Writing Emails to Faculty: An Examination of E-Politeness among Native and Non-Native Speakers of English

ERIC Educational Resources Information Center

Biesenbach-Lucas, Sigrun

2007-01-01

This study combines interlanguage pragmatics and speech act research with computer-mediated communication and examines how native and non-native speakers of English formulate low- and high-imposition requests to faculty. While some research claims that email, due to absence of non-verbal cues, encourages informal language, other research has…

Promoting Communities of Practice among Non-Native Speakers of English in Online Discussions

ERIC Educational Resources Information Center

Kim, Hoe Kyeung

2011-01-01

An online discussion involving text-based computer-mediated communication has great potential for promoting equal participation among non-native speakers of English. Several studies claimed that online discussions could enhance the academic participation of non-native speakers of English. However, there is little research around participation…

Native Rights in Canada. Second Edition.

ERIC Educational Resources Information Center

Cumming, Peter A., Ed.; Mickenberg, Neil H., Ed.

Intended as a research and reference tool for Canada's native people and their legal advisers, this book is a comprehensive treatise on the law of aboriginal rights and treaties, the historical pattern of dealing with those rights, and alternative judicial and legislative solutions for the settlement of native claims. Secondarily, it is intended…

How Digital Native Learners Describe Themselves

ERIC Educational Resources Information Center

Thompson, Penny

2015-01-01

Eight university students from the "digital native" generation were interviewed about the connections they saw between technology use and learning, and also their reactions to the popular press claims about their generation. Themes that emerged from the interviews were coded to show patterns in how digital natives describe themselves.…

Institutional innovation in less than ideal conditions: management of commons by an Alaska Native village corporation

Treesearch

Dixie Dayo; Gary Kofinas

2010-01-01

Alaska Natives have experienced less than ideal conditions for engaging in management of their homeland commons. During the first 100 years after the Treaty of Cession of 1867, Alaska Natives received limited recognition by the United States. The Alaska Native Claims Settlement Act of 1971 (ANCSA) was signed into law by President Richard Nixon after tedious...

Alaska Native Rural Development: The NANA Experience. Occasional Paper No. 2.

ERIC Educational Resources Information Center

Gaffney, Michael J.

Faced with the need to build new social and economic institutions following the 1971 Alaska Native Claims Settlement Act, Alaska Natives formed 12 regional non-profit making corporations. One of these, Northwest Arctic Inupiat (NANA), is bringing a human resources development approach to the area in an effort to develop enduring economic and…

Native Hawaiians Study Commission: Report on the Culture, Needs and Concerns of Native Hawaiians. Final Report. Volume II. Claims of Conscience: A Dissenting Study of the Culture, Needs and Concerns of Native Hawaiians.

ERIC Educational Resources Information Center

Department of the Interior, Washington, DC.

Volume II of the final report of the Native Hawaiians Study Commission (NHSC) on the culture, needs, and concerns of native Hawaiians, this book contains a formal dissent to the conclusions and recommendations presented in Volume I made by three of the NHSC commissioners. Its principal criticism is that Volume I fails to address the underlying…

2016 American Indian/Alaska Native/Native Hawaiian Areas (AIANNH) Michigan, Minnesota, and Wisconsin

EPA Pesticide Factsheets

The TIGER/Line shapefiles and related database files (.dbf) are an extract of selected geographic and cartographic information from the U.S. Census Bureau's Master Address File / Topologically Integrated Geographic Encoding and Referencing (MAF/TIGER) Database (MTDB). The MTDB represents a seamless national file with no overlaps or gaps between parts, however, each TIGER/Line shapefile is designed to stand alone as an independent data set, or they can be combined to cover the entire nation. The American Indian/Alaska Native/Native Hawaiian (AIANNH) Areas Shapefile includes the following legal entities: federally recognized American Indian reservations and off-reservation trust land areas, state-recognized American Indian reservations, and Hawaiian home lands (HHLs). The statistical entities included are Alaska Native village statistical areas (ANVSAs), Oklahoma tribal statistical areas (OTSAs), tribal designated statistical areas (TDSAs), and state designated tribal statistical areas (SDTSAs). Joint use areas are also included in this shapefile refer to areas that are administered jointly and/or claimed by two or more American Indian tribes. The Census Bureau designates both legal and statistical joint use areas as unique geographic entities for the purpose of presenting statistical data. The Bureau of Indian Affairs (BIA) within the U.S. Department of the Interior (DOI) provides the list of federally recognized tribes and only provides legal boundary infor

44 CFR 79.2 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... authorized native organization, that has zoning and building code jurisdiction over a particular area having... of each claim (including building and contents payments) exceeding $5,000, and with the cumulative... (building payments only) have been made under such coverage, with cumulative amount of such claims exceeding...

44 CFR 79.2 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... authorized native organization, that has zoning and building code jurisdiction over a particular area having... of each claim (including building and contents payments) exceeding $5,000, and with the cumulative... (building payments only) have been made under such coverage, with cumulative amount of such claims exceeding...

A Summary of Changes in the Status of Alaska Natives.

ERIC Educational Resources Information Center

Alaska Univ., Anchorage. Inst. of Social and Economic Research.

Replication of 78 tables from the 1973 2(c) Report by the Secretary of the Interior using 1980 census information provided data to document the social and economic changes in the status of Alaska Natives since the passage of the Alaska Native Claims Settlement Act. Comparison of 1970 and 1980 data showed an average 2.4% growth rate in the Native…

A Philosopher's War on Poverty of the Stimulus Arguments: A Review of Fiona Cowie's "What's Within? Nativism Reconsidered"

ERIC Educational Resources Information Center

Schoneberger, Ted

2005-01-01

In "What's Within? Nativism Reconsidered" (1999) Fiona Cowie addresses three questions: (1) What is nativism? (2) What is meant by calling some trait "innate"? and (3) What types of evidence should be offered when claiming innateness? This review concentrates on these questions as they pertain to Chomsky's faculties-based account of language…

Native American Historic Context for the United States Military Academy, West Point, New York

DTIC Science & Technology

2006-04-01

Native Americans in the Hudson Highlands Pre-Contact Period A number of American Indian nations have over time either occupied the Hudson Valley...inability of Western legal institutions to grasp American Indian and Alaska Native claims that some places on the planet possess a degree of...archeological sites near the USMA. It contains a brief history of various Native American nations that may have been living in or using the West Point

25 CFR 256.2 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... construction must conform to applicable tribal, county, State, or national codes and to appropriate building... that is claimed to adversely affect the interested party making the request, as provided in part 2 of... (including lands owned by corporations established pursuant to the Alaska Native Claims Settlement Act...

Genetic signature of natural selection in first Americans

PubMed Central

G. Amorim, Carlos Eduardo; Nunes, Kelly; Meyer, Diogo; Comas, David; Bortolini, Maria Cátira; Salzano, Francisco Mauro; Hünemeier, Tábita

2017-01-01

When humans moved from Asia toward the Americas over 18,000 y ago and eventually peopled the New World they encountered a new environment with extreme climate conditions and distinct dietary resources. These environmental and dietary pressures may have led to instances of genetic adaptation with the potential to influence the phenotypic variation in extant Native American populations. An example of such an event is the evolution of the fatty acid desaturases (FADS) genes, which have been claimed to harbor signals of positive selection in Inuit populations due to adaptation to the cold Greenland Arctic climate and to a protein-rich diet. Because there was evidence of intercontinental variation in this genetic region, with indications of positive selection for its variants, we decided to compare the Inuit findings with other Native American data. Here, we use several lines of evidence to show that the signal of FADS-positive selection is not restricted to the Arctic but instead is broadly observed throughout the Americas. The shared signature of selection among populations living in such a diverse range of environments is likely due to a single and strong instance of local adaptation that took place in the common ancestral population before their entrance into the New World. These first Americans peopled the whole continent and spread this adaptive variant across a diverse set of environments. PMID:28193867

Financing Aboriginal Government: The Case of Canada's Eastern Arctic.

ERIC Educational Resources Information Center

Cozzetto, Don

1992-01-01

Describes financial strategies that promote financial autonomy of Native governments. Discusses the creation of trust funds with cash settlements of land claims, continued program funding by the federal government, and financial training for Native peoples in relation to the Nunavut agreement, which created an autonomous Inuit territory in Canada.…

77 FR 13137 - Draft Policy on Consultation with Alaska Native Claims Settlement Act Corporations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-05

... availability and request for comments. SUMMARY: The Department of the Interior is requesting comments on its... limited to: 1. ANCSA Corporation land, water areas and resources; 2. The ability of an ANCSA Corporation... the Department's discretion to engage in consultation. ANCSA Corporation--Any Alaska Native village...

It's Not a Poem. It's My Life: Navajo Singing Identities

ERIC Educational Resources Information Center

Roemer, Kenneth M.

2012-01-01

In this essay, the author aims to further complicate the blurrings of Native poetry and autobiography and to make a plea. His general "complicating" genre claim is that an overlooked but absolutely essential form of Native identity expression--that is both preliterate and contemporary--is the traditional song, especially songs that from a…

On the persistence and detectability of ancient Beothuk mitochondrial DNA genomes in living First Nations peoples.

PubMed

Collier, Ashley; Carr, Steven M

2018-03-29

Claims have long been made as to the survival to the present day of descendants of the Newfoundland Beothuk, a group generally accepted to have become extinct with the death of the last known member, Shanawdithit, in 1829. Interest has recently been revived by the availability of commercial genetic testing, which some claim can assign living individuals to specific Native American groups. We compare complete mitogenome sequences (16569 bp) from aDNA of eight distinct Beothuk lineages, including Shanawdithit's uncle Nonosabasut and his wife Demasduit, with three Newfoundland Mi'kmaq lineages and 21 other living Native Americans drawn from GenBank. A Newfoundland Mi'kmaq lineage in Haplogroup A is more similar to three Native Americans (1-3 SNPs) than to the most closely related Beothuk (24 SNPs). Nonosabasut in Haplogroup X is identical to a non-Beothuk Native American. Demasduit in Haplogroup C differs from three other Native Americans by 1-4 substitutions. Within a 2168 bp region of the HVS sequences available from living Mi'kmaq of the Miawpukek First Nation in Newfoundland, lineages in Haplogroups C, X, and A differ by 1, 4, and 8 substitutions, from the most similar Beothuk, and are more similar to other Native Americans. MtDNA genome sequences in living persons identical or similar to those of Beothuk do not necessarily indicate Beothuk ancestry. Mi'kmaq lineages cannot at this time be associated with any Beothuk lineages more closely than those of other Native Americans.

The Colonial Era. An Eyewitness History.

ERIC Educational Resources Information Center

Jaycox, Faith

To the explorer or colonist of the 16th and 17th centuries, North America was a vast and uncharted land. The continent appealed to European eyes--blind to the claims of the Native Americans who, to varying degrees of density, inhabited the entire continent--as an open field to claim, to exploit, and to settle. Once permanent settlements were…

Out of the Woods: The Making of the Maine Indian Claims Settlement Act

ERIC Educational Resources Information Center

Kotlowski, Dean J.

2006-01-01

"Maine appears out of the woods," the editor of the "Lewiston Evening Journal" opined, after President Jimmy Carter signed the Maine Indian Claims Settlement Act in 1980. That sigh of relief was heartfelt. During the 1970s, two Native American tribes, the Passamaquoddies and Penobscots, had sparked a long, statewide nightmare…

The Popular Profile of the Digital Learner: Technology Use Patterns and Approaches to Learning

ERIC Educational Resources Information Center

Thompson, Penny Marie

2012-01-01

The purpose of this study was to investigate the claims made in the popular press about the "digital native" generation as learners. Because students' lives today are saturated with digital media at a time when their brains are still developing, many popular press authors claim that this generation of students thinks and learns…

Discrimination in the TESOL Profession in Mexico: Voices and Perspectives of English as a Foreign Language Teachers

ERIC Educational Resources Information Center

Garcia-Ponce, Edgar Emmanuell; Lengeling, M. M.; Mora-Pablo, I.

2017-01-01

Over the last three decades, research has centred the attention on discrimination within TESOL motivated by issues concerning the distinction between native- and non-native English speaking teachers. However, based upon the authors' experience as English as a Foreign Language (EFL) teachers and researchers, it is claimed that discrimination in…

On the Applicability of Cultural Scripts in Teaching L2 Compliments

ERIC Educational Resources Information Center

Karimnia, Amin; Afghari, Akbar

2010-01-01

In this study, Natural Semantic Metalanguage (henceforth NSM) was used to carry out a comparative analysis. The compliment response behavior of native Persian speakers was compared with that of Native American English speakers to see if it can provide evidence for applicability of NSM model which is claimed to be universal. The descriptive…

Seven Hypotheses on Language Loss Causes and Cures.

ERIC Educational Resources Information Center

Crawford, James

Objective evidence indicates that despite public fears and the claims of those who would make English the official language of the United States, it is not English, but minority tongues that are threatened in this country today. In the last 5 years, educators have noticed a sharp decline in native language skills among Native American children.…

The Role of Interaction in Native Speaker Comprehension of Nonnative Speaker Speech.

ERIC Educational Resources Information Center

Polio, Charlene; Gass, Susan M.

1998-01-01

Because interaction gives language learners an opportunity to modify their speech upon a signal of noncomprehension, it should also have a positive effect on native speakers' (NS) comprehension of nonnative speakers (NNS). This study shows that interaction does help NSs comprehend NNSs, contrasting the claims of an earlier study that found no…

Land use maps of the Tanana and Purcell Mountain areas, Alaska, based on Earth Resources Technology Satellite imagery

NASA Technical Reports Server (NTRS)

Anderson, J. H. (Principal Investigator)

1974-01-01

The author has identified the following significant results. ERTS imagery in photographic format was used to make land use maps of two areas of special interest to native corporations under terms of the Alaska Native Claims Settlement Act. Land selections are to be made in these areas, and the maps should facilitate decisions because of their comprehensive presentation of resource distribution information. The ERTS images enabled mapping broadly-defined land use classes in large areas in a comparatively short time. Some aerial photography was used to identify colors and shades of gray on the various images. The 14 mapped land use categories are identified according to the classification system under development by the U.S. Geological Survey. These maps exemplify a series of about a dozen diverse Alaskan areas. The principal resource depicted is vegetation, and clearly shown are vegetation units of special importance, including stands possibly containing trees of commercial grade and stands constituting wildlife habitat.

The ancestry and affiliations of Kennewick Man.

PubMed

Rasmussen, Morten; Sikora, Martin; Albrechtsen, Anders; Korneliussen, Thorfinn Sand; Moreno-Mayar, J Víctor; Poznik, G David; Zollikofer, Christoph P E; de León, Marcia Ponce; Allentoft, Morten E; Moltke, Ida; Jónsson, Hákon; Valdiosera, Cristina; Malhi, Ripan S; Orlando, Ludovic; Bustamante, Carlos D; Stafford, Thomas W; Meltzer, David J; Nielsen, Rasmus; Willerslev, Eske

2015-07-23

Kennewick Man, referred to as the Ancient One by Native Americans, is a male human skeleton discovered in Washington state (USA) in 1996 and initially radiocarbon dated to 8,340-9,200 calibrated years before present (BP). His population affinities have been the subject of scientific debate and legal controversy. Based on an initial study of cranial morphology it was asserted that Kennewick Man was neither Native American nor closely related to the claimant Plateau tribes of the Pacific Northwest, who claimed ancestral relationship and requested repatriation under the Native American Graves Protection and Repatriation Act (NAGPRA). The morphological analysis was important to judicial decisions that Kennewick Man was not Native American and that therefore NAGPRA did not apply. Instead of repatriation, additional studies of the remains were permitted. Subsequent craniometric analysis affirmed Kennewick Man to be more closely related to circumpacific groups such as the Ainu and Polynesians than he is to modern Native Americans. In order to resolve Kennewick Man's ancestry and affiliations, we have sequenced his genome to ∼1× coverage and compared it to worldwide genomic data including for the Ainu and Polynesians. We find that Kennewick Man is closer to modern Native Americans than to any other population worldwide. Among the Native American groups for whom genome-wide data are available for comparison, several seem to be descended from a population closely related to that of Kennewick Man, including the Confederated Tribes of the Colville Reservation (Colville), one of the five tribes claiming Kennewick Man. We revisit the cranial analyses and find that, as opposed to genome-wide comparisons, it is not possible on that basis to affiliate Kennewick Man to specific contemporary groups. We therefore conclude based on genetic comparisons that Kennewick Man shows continuity with Native North Americans over at least the last eight millennia.

Of Hating, Hurting, and Coming to Terms with the English Language.

ERIC Educational Resources Information Center

Keeshig-Tobias, Lenore

2003-01-01

For Canada Natives, storytelling and describing dreams are the beginnings of literacy. Many elders survived abuse in residential schools because of language, and claim that one cannot be Indian without the language. This author works in English, yet her writings are informed by Native culture. Language can be a tool or a weapon; it depends on how…

To direct the Secretary of the Interior to convey certain Federal property located in the National Petroleum Reserve in Alaska to the Olgoonik Corporation, an Alaska Native Corporation established under the Alaska Native Claims Settlement Act.

THOMAS, 113th Congress

Rep. Young, Don [R-AK-At Large

2014-07-22

Senate - 11/17/2014 Received in the Senate and Read twice and referred to the Committee on Energy and Natural Resources. (All Actions) Tracker: This bill has the status Passed HouseHere are the steps for Status of Legislation:

Coast Guard: Efforts to Identify Arctic Requirements Are Ongoing, but More Communication about Agency Planning Efforts Would Be Beneficial

DTIC Science & Technology

2010-09-01

involve Indian tribal governments, such as certain Arctic indigenous communities in Alaska , in decisions that affect them.14 Finally, since the Arctic...primarily as vehicles for distributing land and monetary benefits to Alaska Natives to provide a fair and just settlement of aboriginal land claims in... Alaska Native stakeholders, as well as private or nonprofit organizations representing Arctic interests. These observations are not

The Impact of Nutrition and Health Claims on Consumer Perceptions and Portion Size Selection: Results from a Nationally Representative Survey.

PubMed

Benson, Tony; Lavelle, Fiona; Bucher, Tamara; McCloat, Amanda; Mooney, Elaine; Egan, Bernadette; Collins, Clare E; Dean, Moira

2018-05-22

Nutrition and health claims on foods can help consumers make healthier food choices. However, claims may have a 'halo' effect, influencing consumer perceptions of foods and increasing consumption. Evidence for these effects are typically demonstrated in experiments with small samples, limiting generalisability. The current study aimed to overcome this limitation through the use of a nationally representative survey. In a cross-sectional survey of 1039 adults across the island of Ireland, respondents were presented with three different claims (nutrition claim = "Low in fat"; health claim = "With plant sterols. Proven to lower cholesterol"; satiety claim = "Fuller for longer") on four different foods (cereal, soup, lasagne, and yoghurt). Participants answered questions on perceived healthiness, tastiness, and fillingness of the products with different claims and also selected a portion size they would consume. Claims influenced fillingness perceptions of some of the foods. However, there was little influence of claims on tastiness or healthiness perceptions or the portion size selected. Psychological factors such as consumers' familiarity with foods carrying claims and belief in the claims were the most consistent predictors of perceptions and portion size selection. Future research should identify additional consumer factors that may moderate the relationships between claims, perceptions, and consumption.

The Impact of Nutrition and Health Claims on Consumer Perceptions and Portion Size Selection: Results from a Nationally Representative Survey

PubMed Central

Benson, Tony; Lavelle, Fiona; McCloat, Amanda; Mooney, Elaine; Egan, Bernadette; Collins, Clare E.; Dean, Moira

2018-01-01

Nutrition and health claims on foods can help consumers make healthier food choices. However, claims may have a ‘halo’ effect, influencing consumer perceptions of foods and increasing consumption. Evidence for these effects are typically demonstrated in experiments with small samples, limiting generalisability. The current study aimed to overcome this limitation through the use of a nationally representative survey. In a cross-sectional survey of 1039 adults across the island of Ireland, respondents were presented with three different claims (nutrition claim = “Low in fat”; health claim = “With plant sterols. Proven to lower cholesterol”; satiety claim = “Fuller for longer”) on four different foods (cereal, soup, lasagne, and yoghurt). Participants answered questions on perceived healthiness, tastiness, and fillingness of the products with different claims and also selected a portion size they would consume. Claims influenced fillingness perceptions of some of the foods. However, there was little influence of claims on tastiness or healthiness perceptions or the portion size selected. Psychological factors such as consumers’ familiarity with foods carrying claims and belief in the claims were the most consistent predictors of perceptions and portion size selection. Future research should identify additional consumer factors that may moderate the relationships between claims, perceptions, and consumption. PMID:29789472

An invasive plant alters pollinator-mediated phenotypic selection on a native congener.

PubMed

Beans, Carolyn M; Roach, Deborah A

2015-01-01

• Recent studies suggest that invasive plants compete reproductively with native plants by reducing the quantity or quality of pollinator visits. Although these studies have revealed ecological consequences of pollinator-mediated competition between invasive and native plants, the evolutionary outcomes of these interactions remain largely unexplored.• We studied the ecological and evolutionary impact of pollinator-mediated competition with an invasive jewelweed, Impatiens glandulifera, on a co-occurring native congener, I. capensis. Using a pollinator choice experiment, a hand pollination experiment, and a selection analysis, we addressed the following questions: (1) Do native pollinators show preference for the invasive or native jewelweed, and do they move between the two species? (2) Does invasive jewelweed pollen inhibit seed production in the native plant? (3) Does the invasive jewelweed alter phenotypic selection on the native plant's floral traits?• The pollinator choice experiment showed that pollinators strongly preferred the invasive jewelweed. The hand pollination experiment demonstrated that invasive pollen inhibited seed production in the native plant. The selection analysis showed that the presence of the invasive jewelweed altered phenotypic selection on corolla height in the native plant.• Invasive plants have the potential to alter phenotypic selection on floral traits in native plant populations. If native plants can evolve in response to this altered selection pressure, the evolution of floral traits may play an important role in permitting long-term coexistence of native and invasive plants. © 2015 Botanical Society of America, Inc.

Dispersal and selection mediate hybridization between a native and invasive species

USGS Publications Warehouse

Kovach, Ryan P.; Muhlfeld, Clint C.; Boyer, Matthew C.; Lowe, Winsor H.; Allendorf, Fred W.; Luikart, Gordon

2015-01-01

Hybridization between native and non-native species has serious biological consequences, but our understanding of how dispersal and selection interact to influence invasive hybridization is limited. Here, we document the spread of genetic introgression between a native (Oncorhynchus clarkii) and invasive (Oncorhynchus mykiss) trout, and identify the mechanisms influencing genetic admixture. In two populations inhabiting contrasting environments, non-native admixture increased rapidly from 1984 to 2007 and was driven by surprisingly consistent processes. Individual admixture was related to two phenotypic traits associated with fitness: size at spawning and age of juvenile emigration. Fish with higher non-native admixture were larger and tended to emigrate at a younger age—relationships that are expected to confer fitness advantages to hybrid individuals. However, strong selection against non-native admixture was evident across streams and cohorts (mean selection coefficient against genotypes with non-native alleles (s) ¼ 0.60; s.e. ¼ 0.10). Nevertheless, hybridization was promoted in both streams by the continuous immigration of individuals with high levels of non-native admixture from other hybrid source populations. Thus, antagonistic relationships between dispersal and selection are mediating invasive hybridization between these fish, emphasizing that data on dispersal and natural selection are needed to fully understand the dynamics of introgression between native and non-native species. .

Biological activity analysis of native and recombinant streptokinase using clot lysis and chromogenic substrate assay.

PubMed

Mahboubi, Arash; Sadjady, Seyyed Kazem; Mirzaei Saleh Abadi, Mohammad; Azadi, Saeed; Solaimanian, Roya

2012-01-01

DETERMINATION OF STREPTOKINASE ACTIVITY IS USUALLY ACCOMPLISHED THROUGH TWO ASSAY METHODS: a) Clot lysis, b) Chromogenic substrate assay. In this study the biological activity of two streptokinase products, namely Streptase®, which is a native product and Heberkinasa®, which is a recombinant product, was determined against the third international reference standard using the two forementioned assay methods. The results indicated that whilst the activity of Streptase® was found to be 101 ± 4% and 97 ± 5% of the label claim with Clot lysis and Chromogenic substrate assay respectively, for Heberkinasa® the potency values obtained were 42 ± 5% and 92.5 ± 2% of the label claim respectively. To shed some light on the reason for this finding, the n-terminal sequence of the streptokinase molecules present in the two products was determined. The results showed slight differences in the amino acid sequence of the recombinant product in comparison to the native one at the amino terminus. This finding supports those of other workers who found that n-terminal sequence of the streptokinase molecule can have significant effect on the activity of this protein.

20 CFR 405.410 - Selecting claims for Decision Review Board review.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Selecting claims for Decision Review Board review. 405.410 Section 405.410 Employees' Benefits SOCIAL SECURITY ADMINISTRATION ADMINISTRATIVE REVIEW... will not review claims based on the identity of the administrative law judge who decided the claim. (b...

Dispersal and selection mediate hybridization between a native and invasive species.

PubMed

Kovach, Ryan P; Muhlfeld, Clint C; Boyer, Matthew C; Lowe, Winsor H; Allendorf, Fred W; Luikart, Gordon

2015-01-22

Hybridization between native and non-native species has serious biological consequences, but our understanding of how dispersal and selection interact to influence invasive hybridization is limited. Here, we document the spread of genetic introgression between a native (Oncorhynchus clarkii) and invasive (Oncorhynchus mykiss) trout, and identify the mechanisms influencing genetic admixture. In two populations inhabiting contrasting environments, non-native admixture increased rapidly from 1984 to 2007 and was driven by surprisingly consistent processes. Individual admixture was related to two phenotypic traits associated with fitness: size at spawning and age of juvenile emigration. Fish with higher non-native admixture were larger and tended to emigrate at a younger age--relationships that are expected to confer fitness advantages to hybrid individuals. However, strong selection against non-native admixture was evident across streams and cohorts (mean selection coefficient against genotypes with non-native alleles (s) = 0.60; s.e. = 0.10). Nevertheless, hybridization was promoted in both streams by the continuous immigration of individuals with high levels of non-native admixture from other hybrid source populations. Thus, antagonistic relationships between dispersal and selection are mediating invasive hybridization between these fish, emphasizing that data on dispersal and natural selection are needed to fully understand the dynamics of introgression between native and non-native species. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

A Philosopher's War on Poverty of the Stimulus Arguments: A Review of Fiona Cowie's What's Within? Nativism Reconsidered.

PubMed

Schoneberger, Ted

2005-01-01

In What's Within? Nativism Reconsidered 1999 Fiona Cowie addresses three questions: (1) What is nativism? (2) What is meant by calling some trait "innate"? and (3) What types of evidence should be offered when claiming innateness? This review concentrates on these questions as they pertain to Chomsky's faculties-based account of language acquisition. In particular, this review focuses on Cowie's critique of three versions of the poverty of the stimulus argument (POSA): (1) the a posteriori POSA, (2) the logical problem POSA, and (3) the iterated POSA. In addition, counter arguments to her critique, and Cowie's response, in turn, to some of those counter arguments, are also reviewed.

78 FR 72711 - Notice of Intent To Repatriate Cultural Items: U.S. Department of the Interior, Bureau of Land...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-03

...The U.S. Department of the Interior, Bureau of Land Management (BLM), Alaska State Office, in consultation with the appropriate Indian tribes or Native Hawaiian organizations, has determined that the items listed in this notice meet the definition of unassociated funerary objects. Lineal descendants or representatives of any Indian tribe or Native Hawaiian organization not identified in this notice that wish to claim these items should submit a written request to the BLM Alaska State Office. If no additional claimants come forward, transfer of control of the items to the lineal descendants, Indian tribes, or Native Hawaiian organizations stated in this notice may proceed.

Selective herbicide applications for low impact vegetation management of exotic species and enhancement of native plant communities

Treesearch

Max Williamson

1998-01-01

Selective and specific management for the control of exotic (non-native) plants is necessary for preservation of native plant communities. Managers of federal, state, or county land holdings and parks, wildlife areas, recreation areas, and historic sites are frequently charged with selectively managing the enhancement of desirable or native plant communities. In...

Evaluation of an Ultrafast Molecular Rotor, Auramine O, as a Fluorescent Amyloid Marker.

PubMed

Mudliar, Niyati H; Sadhu, Biswajit; Pettiwala, Aafrin M; Singh, Prabhat K

2016-10-13

Recently, Auramine O (AuO) has been projected as a fluorescent fibril sensor, and it has been claimed that AuO has an advantage over the most extensively utilized fibril marker, Thioflavin-T (ThT), owing to the presence of an additional large red-shifted emission band for AuO, which was observed exclusively for AuO in the presence of fibrillar media and not in protein or buffer media. As fibrils are very rich in β-sheet structure, a fibril sensor should be more specific toward the β-sheet structure so as to produce a large contrast between the fibril form and native protein form, for efficient detection and in vitro mechanistic studies of fibrillation. However, in this report, we show that AuO interacts significantly with the native form of bovine serum albumin (BSA), which is an all-α-helical protein and lacks the β-sheet structure, which are the hallmarks of a fibrillar structure. This strong interaction of AuO with the native form of BSA leads to a large emission enhancement of AuO for the native protein itself, and leads to a low contrast between the BSA protein and its fibrils. More importantly, the large red-shifted emission band of AuO, reported in the presence of human insulin fibrils, and which was projected as its major advantage over ThT, is not observed in the presence of BSA fibrils as well as fibrils from other proteins, such as lysozyme, human serum albumin, and β-lactoglobulin. Thus, our results provide information on the universal applicability of the distinctive and claimed-to-be-advantageous photophysical features reported for AuO in human insulin fibrils towards fibrils from other proteins. Time-resolved fluorescence measurements also support the proposition of a strong interaction of AuO with native BSA. Additionally, tryptophan emission of the protein has been explored to further elucidate the binding mechanism of AuO with native BSA. Evaluation of thermodynamic parameters revealed that the binding of AuO with native BSA involved positive enthalpy and entropy changes, suggesting dominant contributions from hydrophobic and electrostatic interactions toward the association of AuO with native BSA. Molecular docking calculations have been performed to identify the principal binding location of AuO in native BSA.

Native Americans and state and local governments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rusco, E.R.

1991-10-01

Native Americans` concerns arising from the possibility of establishment of a nuclear repository for high level wastes at Yucca Mountain fall principally into two main categories. First, the strongest objection to the repository comes from traditional Western Shoshones. Their objections are based on a claim that the Western Shoshones still own Yucca Mountain and also on the assertion that putting high level nuclear wastes into the ground is a violation of their religious views regarding nature. Second, there are several reservations around the Yucca Mountain site that might be affected in various ways by building of the repository. There ismore » a question about how many such reservations there are, which can only be decided when more information is available. This report discusses two questions: the bearing of the continued vigorous assertion by traditionalist Western Shoshones of their land claim; and the extent to which Nevada state and local governments are able to understand and represent Indian viewpoints about Yucca Mountain.« less

SELECTING AND EVALUATING NATIVE PLANTS FOR REGION-SPECIFIC PHYTOTOXICITY TESTING

EPA Science Inventory

In this study, we evaluated methodology to determine risks to terrestrial native plant species from potential herbicide drift, focusing on 1) selection of native species for testing, 2) growth of these species, and 3) variability in herbicide response among native species and com...

A Philosopher's War on Poverty of the Stimulus Arguments: A Review of Fiona Cowie's What's Within? Nativism Reconsidered

PubMed Central

Schoneberger, Ted

2005-01-01

In What's Within? Nativism Reconsidered 1999 Fiona Cowie addresses three questions: (1) What is nativism? (2) What is meant by calling some trait “innate”? and (3) What types of evidence should be offered when claiming innateness? This review concentrates on these questions as they pertain to Chomsky's faculties-based account of language acquisition. In particular, this review focuses on Cowie's critique of three versions of the poverty of the stimulus argument (POSA): (1) the a posteriori POSA, (2) the logical problem POSA, and (3) the iterated POSA. In addition, counter arguments to her critique, and Cowie's response, in turn, to some of those counter arguments, are also reviewed. PMID:22477325

24 CFR 954.4 - Other Federal requirements.

Code of Federal Regulations, 2011 CFR

2011-04-01

... regional or village corporation as defined or established pursuant to the Alaska Native Claims Settlement..., and affordable dwelling unit in the building/complex upon completion of the project. (2) Temporary... building/complex upon completion of the project; and (D) The provisions of paragraph (e)(2)(i) of this...

Biopiracy and Native Knowledge: Indigenous Rights on the Last Frontier.

ERIC Educational Resources Information Center

Benjamin, Craig

1997-01-01

In the past few years, transnational corporations and university researchers received patents for traditional medicines and for food and textile plants used by indigenous peoples without returning any benefits to those peoples. In light of U.S. and Canadian government claims that traditional knowledge is not intellectual property, indigenous…

Chomsky's 'Ideal' Native Speaker: Sexism in Synchronic Linguistics.

ERIC Educational Resources Information Center

Stanley, Julia Penelope

Drawing on recent research on sexism in English and the ways in which social forces affect language structure, this paper shows how prescriptive statements about English have been incorporated into linguistic grammars as descriptions of language. It is claimed that Chomsky's "universal grammar" is masculinist and that it is contradicted…

Native American Higher Education in the United States.

ERIC Educational Resources Information Center

Carney, Cary Michael

This book presents a comprehensive history of higher education for American Indians. Following an introduction, chapter 2 covers the Colonial Period, from European contact to the establishment of the U.S. Government. Some of the earliest universities, most notably Harvard, Dartmouth, and William and Mary, specifically claimed to have had American…

Detecting Positive Selection of Korean Native Goat Populations Using Next-Generation Sequencing

PubMed Central

Lee, Wonseok; Ahn, Sojin; Taye, Mengistie; Sung, Samsun; Lee, Hyun-Jeong; Cho, Seoae; Kim, Heebal

2016-01-01

Goats (Capra hircus) are one of the oldest species of domesticated animals. Native Korean goats are a particularly interesting group, as they are indigenous to the area and were raised in the Korean peninsula almost 2,000 years ago. Although they have a small body size and produce low volumes of milk and meat, they are quite resistant to lumbar paralysis. Our study aimed to reveal the distinct genetic features and patterns of selection in native Korean goats by comparing the genomes of native Korean goat and crossbred goat populations. We sequenced the whole genome of 15 native Korean goats and 11 crossbred goats using next-generation sequencing (Illumina platform) to compare the genomes of the two populations. We found decreased nucleotide diversity in the native Korean goats compared to the crossbred goats. Genetic structural analysis demonstrated that the native Korean goat and crossbred goat populations shared a common ancestry, but were clearly distinct. Finally, to reveal the native Korean goat’s selective sweep region, selective sweep signals were identified in the native Korean goat genome using cross-population extended haplotype homozygosity (XP-EHH) and a cross-population composite likelihood ratio test (XP-CLR). As a result, we were able to identify candidate genes for recent selection, such as the CCR3 gene, which is related to lumbar paralysis resistance. Combined with future studies and recent goat genome information, this study will contribute to a thorough understanding of the native Korean goat genome. PMID:27989103

Detecting Positive Selection of Korean Native Goat Populations Using Next-Generation Sequencing.

PubMed

Lee, Wonseok; Ahn, Sojin; Taye, Mengistie; Sung, Samsun; Lee, Hyun-Jeong; Cho, Seoae; Kim, Heebal

2016-12-01

Goats ( Capra hircus ) are one of the oldest species of domesticated animals. Native Korean goats are a particularly interesting group, as they are indigenous to the area and were raised in the Korean peninsula almost 2,000 years ago. Although they have a small body size and produce low volumes of milk and meat, they are quite resistant to lumbar paralysis. Our study aimed to reveal the distinct genetic features and patterns of selection in native Korean goats by comparing the genomes of native Korean goat and crossbred goat populations. We sequenced the whole genome of 15 native Korean goats and 11 crossbred goats using next-generation sequencing (Illumina platform) to compare the genomes of the two populations. We found decreased nucleotide diversity in the native Korean goats compared to the crossbred goats. Genetic structural analysis demonstrated that the native Korean goat and crossbred goat populations shared a common ancestry, but were clearly distinct. Finally, to reveal the native Korean goat's selective sweep region, selective sweep signals were identified in the native Korean goat genome using cross-population extended haplotype homozygosity (XP-EHH) and a cross-population composite likelihood ratio test (XP-CLR). As a result, we were able to identify candidate genes for recent selection, such as the CCR3 gene, which is related to lumbar paralysis resistance. Combined with future studies and recent goat genome information, this study will contribute to a thorough understanding of the native Korean goat genome.

Vive la résistance: genome-wide selection against introduced alleles in invasive hybrid zones

USGS Publications Warehouse

Kovach, Ryan P.; Hand, Brian K.; Hohenlohe, Paul A.; Cosart, Ted F.; Boyer, Matthew C.; Neville, Helen H.; Muhlfeld, Clint C.; Amish, Stephen J.; Carim, Kellie; Narum, Shawn R.; Lowe, Winsor H.; Allendorf, Fred W.; Luikart, Gordon

2016-01-01

Evolutionary and ecological consequences of hybridization between native and invasive species are notoriously complicated because patterns of selection acting on non-native alleles can vary throughout the genome and across environments. Rapid advances in genomics now make it feasible to assess locus-specific and genome-wide patterns of natural selection acting on invasive introgression within and among natural populations occupying diverse environments. We quantified genome-wide patterns of admixture across multiple independent hybrid zones of native westslope cutthroat trout and invasive rainbow trout, the world's most widely introduced fish, by genotyping 339 individuals from 21 populations using 9380 species-diagnostic loci. A significantly greater proportion of the genome appeared to be under selection favouring native cutthroat trout (rather than rainbow trout), and this pattern was pervasive across the genome (detected on most chromosomes). Furthermore, selection against invasive alleles was consistent across populations and environments, even in those where rainbow trout were predicted to have a selective advantage (warm environments). These data corroborate field studies showing that hybrids between these species have lower fitness than the native taxa, and show that these fitness differences are due to selection favouring many native genes distributed widely throughout the genome.

Mitochondrial DNA analysis reveals substantial Native American ancestry in Puerto Rico.

PubMed

Martínez-Cruzado, J C; Toro-Labrador, G; Ho-Fung, V; Estévez-Montero, M A; Lobaina-Manzanet, A; Padovani-Claudio, D A; Sánchez-Cruz, H; Ortiz-Bermúdez, P; Sánchez-Crespo, A

2001-08-01

To estimate the maternal contribution of Native Americans to the human gene pool of Puerto Ricans--a population of mixed African, European, and Amerindian ancestry--the mtDNAs of two sample sets were screened for restriction fragment length polymorphisms (RFLPs) defining the four major Native American haplogroups. The sample set collected from people who claimed to have a maternal ancestor with Native American physiognomic traits had a statistically significant higher frequency of Native American mtDNAs (69.6%) than did the unbiased sample set (52.6%). This higher frequency suggests that, despite the fact that the native Taíno culture has been extinct for centuries, the Taíno contribution to the current population is considerable and some of the Taíno physiognomic traits are still present. Native American haplogroup frequency analysis shows a highly structured distribution, suggesting that the contribution of Native Americans foreign to Puerto Rico is minimal. Haplogroups A and C cover 56.0% and 35.6% of the Native American mtDNAs, respectively. No haplogroup D mtDNAs were found. Most of the linguistic, biological, and cultural evidence suggests that the Ceramic culture of the Taínos originated in or close to the Yanomama territory in the Amazon. However, the absence of haplogroup A in the Yanomami suggests that the Yanomami are not the only Taíno ancestors.

Inulin-type fructans: functional food ingredients.

PubMed

Roberfroid, Marcel B

2007-11-01

A food (ingredient) is regarded as functional if it is satisfactorily demonstrated to affect beneficially 1 or more target functions in the body beyond adequate nutritional effects. The term inulin-type fructans covers all beta(2<--1) linear fructans including native inulin (DP 2-60, DP(av) = 12), oligofructose (DP 2-8, DP(av) = 4), and inulin HP (DP 10-60, DP(av) = 25) as well as Synergy 1, a specific combination of oligofructose and inulin HP. Inulin-type fructans resist digestion and function as dietary fiber improving bowel habits. But, unlike most dietary fibers, their colonic fermentation is selective, thus causing significant changes in the composition of the gut microflora with increased and reduced numbers of potentially health-promoting bacteria and potentially harmful species, respectively. Both oligofructose and inulin act in this way and thus are prebiotic: they also induce changes in the colonic epithelium and in miscellaneous colonic functions. In particular, the claim "inulin-type fructans enhance calcium and magnesium absorption" is scientifically substantiated, and the most active product is oligofructose-enriched inulin (Synergy 1). A series of studies furthermore demonstrate that inulin-type fructans modulate the secretion of gastrointestinal peptides involved in appetite regulation as well as lipid metabolism. Moreover, a large number of animal studies and preliminary human data show that inulin-type fructans reduce the risk of colon carcinogenesis and improve the management of inflammatory bowel diseases. Inulin-type fructans are thus functional food ingredients that are eligible for enhanced function claims, but, as more human data become available, risk reduction claims will become scientifically substantiated.

Great Basin Native Plant Selection and Increase Project: 2012 progress report

Treesearch

Nancy Shaw; Mike Pellant

2013-01-01

The Interagency Native Plant Materials Development Program outlined in the 2002 USDA and USDI Report to Congress, USDI Bureau of Land Management programs and policies, and the Great Basin Restoration Initiative encourage the use of native species for rangeland rehabilitation and restoration where feasible. The Great Basin Native Plant Selection and Increase Project was...

77 FR 37605 - Registration of Claims to Copyright

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-22

... in selection and arrangement of exercises or of other uncopyrightable matter. The statement also... practices with respect to claims in ``compilation authorship,'' or the selection, coordination, or... registration based on the selection, coordination, or arrangement of uncopyrightable elements, because the...

Ethnic and gender differences in ideal body size and related attitudes among Asians, Native Hawaiians, and Whites.

PubMed

Townsend, Claire; Takishima-Lacasa, Julie Y; Latner, Janet D; Grandinetti, Andrew; Keawe'aimoku Kaholokula, Joseph

2014-08-01

Often overlooked explanations for the varied obesity rates across ethno-cultural groups include differences in attitudes toward excess weight, with certain populations assumed to have larger ideal body sizes (IBS). Past studies found ethnic and gender difference in IBS across and within different groups. This study examined the effects of ethnicity and gender, and their interaction, in accounting for differences in IBS and attitudes toward those ideals. Multiple regression analyses were used to better understand the effects of ethnicity and gender in accounting for differences in perceived IBS according to ethnic-specific and Western ideals and attitudes in 1,124 people of Native Hawaiian, Filipino, Japanese, and White ancestry. The analyses controlled for socio-demographics, body mass index, health-related behaviors, and psychosocial variables. The results indicated that Native Hawaiians selected larger ethnic IBS, Filipinos selected smaller ethnic IBS, and Native Hawaiians selected slightly smaller Western IBS than other ethnic groups. Overall, males selected larger IBS compared to females. Interaction analyses indicated that the relationship between ethnic IBS and attitude toward that IBS varied as a function of ethnicity, such that Native Hawaiians who selected a larger ethnic IBS held less favorable attitudes toward that IBS. The discrepancy between Native Hawaiians' selection of larger ethnic IBS as ideal and their less positive attitude toward that selection warrants more investigation. However, it does suggest that Native Hawaiians, on a personal level, do not prefer larger body sizes, which contradicts their perceptions of social norms. These findings have important implications for obesity interventions among Native Hawaiians.

Ethnic and Gender Differences in Ideal Body Size and Related Attitudes among Asians, Native Hawaiians, and Whites

PubMed Central

Takishima-Lacasa, Julie Y; Latner, Janet D; Grandinetti, Andrew; Keawe‘aimoku Kaholokula, Joseph

2014-01-01

Often overlooked explanations for the varied obesity rates across ethno-cultural groups include differences in attitudes toward excess weight, with certain populations assumed to have larger ideal body sizes (IBS). Past studies found ethnic and gender difference in IBS across and within different groups. This study examined the effects of ethnicity and gender, and their interaction, in accounting for differences in IBS and attitudes toward those ideals. Multiple regression analyses were used to better understand the effects of ethnicity and gender in accounting for differences in perceived IBS according to ethnic-specific and Western ideals and attitudes in 1,124 people of Native Hawaiian, Filipino, Japanese, and White ancestry. The analyses controlled for socio-demographics, body mass index, health-related behaviors, and psychosocial variables. The results indicated that Native Hawaiians selected larger ethnic IBS, Filipinos selected smaller ethnic IBS, and Native Hawaiians selected slightly smaller Western IBS than other ethnic groups. Overall, males selected larger IBS compared to females. Interaction analyses indicated that the relationship between ethnic IBS and attitude toward that IBS varied as a function of ethnicity, such that Native Hawaiians who selected a larger ethnic IBS held less favorable attitudes toward that IBS. The discrepancy between Native Hawaiians' selection of larger ethnic IBS as ideal and their less positive attitude toward that selection warrants more investigation. However, it does suggest that Native Hawaiians, on a personal level, do not prefer larger body sizes, which contradicts their perceptions of social norms. These findings have important implications for obesity interventions among Native Hawaiians. PMID:25157324

Influences of Native American land use on the Colonial Euro-American settlement of the South Carolina Piedmont

PubMed Central

Nelson, Donald R.

2018-01-01

We test the hypothesis that prehistoric Native American land use influenced the Euro-American settlement process in a South Carolina Piedmont landscape. Long term ecological studies demonstrate that land use legacies influence processes and trajectories in complex, coupled social and ecological systems. Native American land use likely altered the ecological and evolutionary feedback and trajectories of many North American landscapes. Yet, considerable debate revolves around the scale and extent of land use legacies of prehistoric Native Americans. At the core of this debate is the question of whether or not European colonists settled a mostly “wild” landscape or an already “humanized” landscape. We use statistical event analysis to model the effects of prehistoric Native American settlement on the rate of Colonial land grants (1749–1775). Our results reveal how abandoned Native American settlements were among the first areas claimed and homesteaded by Euro-Americans. We suggest that prehistoric land use legacies served as key focal nodes in the Colonial era settlement process. As a consequence, localized prehistoric land use legacies likely helped structure the long term, landscape- to regional-level ecological inheritances that resulted from Euro-American settlement. PMID:29596504

Influences of Native American land use on the Colonial Euro-American settlement of the South Carolina Piedmont.

PubMed

Coughlan, Michael R; Nelson, Donald R

2018-01-01

We test the hypothesis that prehistoric Native American land use influenced the Euro-American settlement process in a South Carolina Piedmont landscape. Long term ecological studies demonstrate that land use legacies influence processes and trajectories in complex, coupled social and ecological systems. Native American land use likely altered the ecological and evolutionary feedback and trajectories of many North American landscapes. Yet, considerable debate revolves around the scale and extent of land use legacies of prehistoric Native Americans. At the core of this debate is the question of whether or not European colonists settled a mostly "wild" landscape or an already "humanized" landscape. We use statistical event analysis to model the effects of prehistoric Native American settlement on the rate of Colonial land grants (1749-1775). Our results reveal how abandoned Native American settlements were among the first areas claimed and homesteaded by Euro-Americans. We suggest that prehistoric land use legacies served as key focal nodes in the Colonial era settlement process. As a consequence, localized prehistoric land use legacies likely helped structure the long term, landscape- to regional-level ecological inheritances that resulted from Euro-American settlement.

Native language change during early stages of second language learning.

PubMed

Bice, Kinsey; Kroll, Judith F

2015-11-11

Research on proficient bilinguals has demonstrated that both languages are always active, even when only one is required. The coactivation of the two languages creates both competition and convergence, facilitating the processing of cognate words, but slowing lexical access when there is a requirement to engage control mechanisms to select the target language. Critically, these consequences are evident in the native language (L1) as well as in the second language (L2). The present study questioned whether L1 changes can be detected at early stages of L2 learning and how they are modulated by L2 proficiency. Native English speakers learning Spanish performed an English (L1) lexical decision task that included cognates while event-related potentials were recorded. They also performed verbal fluency, working memory, and inhibitory control tasks. A group of matched monolinguals performed the same tasks in English only. The results revealed that intermediate learners demonstrate a reduced N400 for cognates compared with noncognates in English (L1), and an emerging effect is visually present in beginning learners as well; however, no behavioral cognate effect was present for either group. In addition, slower reaction times in English (L1) are related to a larger cognate N400 magnitude in English (L1) and Spanish (L2), and to better inhibitory control for learners but not for monolinguals. The results suggest that contrary to the claim that L2 affects L1 only when L2 speakers are highly proficient, L2 learning begins to impact L1 early in the development of the L2 skill.

Village Science. Teacher's Edition [and Student Edition].

ERIC Educational Resources Information Center

Dick, Alan

This science curriculum was written to inspire rural Alaskans, primarily Alaska Natives, to find science in their local environment. The author lived a subsistence lifestyle in the Alaskan bush for over 30 years and claims that understanding science has often kept him from being stuck out in the woods. Section 1, Skills, Tools, and Craftsmanship,…

49 CFR 23.3 - What do the terms used in this part mean?

Code of Federal Regulations, 2013 CFR

2013-10-01

... accordance with the Alaska Native Claims Settlement Act (43 U.S.C. 1601 et seq.) Car dealership means an establishment primarily engaged in the retail sale of new and/or used automobiles. Car dealerships frequently... industrial classification system, car dealerships are categorized in NAICS code 441110. Concession means one...

43 CFR Appendix A to Part 10 - Sample Summary

Code of Federal Regulations, 2011 CFR

2011-10-01

... cultural patrimony that are, or are likely to be, culturally affiliated with your Indian tribe or Native...,000 items from fifteen sites within the area recognized by the Indian Claims Commission as being part... objects of cultural patrimony in this collection that are, or are likely to be, culturally affiliated with...

Goals for Fourth World Peoples and Sovereignty Initiatives in the United States and New Zealand.

ERIC Educational Resources Information Center

Duffie, Mary Kay

1998-01-01

Compares national policies of the United States and New Zealand toward their indigenous populations, and sovereignty initiatives of Native Americans and Maoris. Discusses colonialist patterns, treaty relationships, historical policy trajectories, and sovereignty disputes. Examines Indian gaming and Maori land claims settlements as a means to gain…

Auditory detection of non-speech and speech stimuli in noise: Effects of listeners' native language background.

PubMed

Liu, Chang; Jin, Su-Hyun

2015-11-01

This study investigated whether native listeners processed speech differently from non-native listeners in a speech detection task. Detection thresholds of Mandarin Chinese and Korean vowels and non-speech sounds in noise, frequency selectivity, and the nativeness of Mandarin Chinese and Korean vowels were measured for Mandarin Chinese- and Korean-native listeners. The two groups of listeners exhibited similar non-speech sound detection and frequency selectivity; however, the Korean listeners had better detection thresholds of Korean vowels than Chinese listeners, while the Chinese listeners performed no better at Chinese vowel detection than the Korean listeners. Moreover, thresholds predicted from an auditory model highly correlated with behavioral thresholds of the two groups of listeners, suggesting that detection of speech sounds not only depended on listeners' frequency selectivity, but also might be affected by their native language experience. Listeners evaluated their native vowels with higher nativeness scores than non-native listeners. Native listeners may have advantages over non-native listeners when processing speech sounds in noise, even without the required phonetic processing; however, such native speech advantages might be offset by Chinese listeners' lower sensitivity to vowel sounds, a characteristic possibly resulting from their sparse vowel system and their greater cognitive and attentional demands for vowel processing.

32 CFR 536.2 - Claims authorities.

Code of Federal Regulations, 2012 CFR

2012-07-01

.../85256F33005C2B92/(JAGCNETDocID)/HOME?OPENDOCUMENT. Select the link “Claims Resources.” (1) Tort claims. (i) The... Secretary of Defense, the Secretary of Transportation, and the Secretary of Health and Human Services. (v... Claims Act (NGCA), 32 U.S.C. 715 (see subpart F of this part). (vii) Claims under International...

32 CFR 536.2 - Claims authorities.

Code of Federal Regulations, 2014 CFR

2014-07-01

.../85256F33005C2B92/(JAGCNETDocID)/HOME?OPENDOCUMENT. Select the link “Claims Resources.” (1) Tort claims. (i) The... Secretary of Defense, the Secretary of Transportation, and the Secretary of Health and Human Services. (v... Claims Act (NGCA), 32 U.S.C. 715 (see subpart F of this part). (vii) Claims under International...

Predation on the Invasive Copepod, Pseudodiaptomus forbesi, and Native Zooplankton in the Lower Columbia River: An Experimental Approach to Quantify Differences in Prey-Specific Feeding Rates

PubMed Central

Adams, Jesse B.; Bollens, Stephen M.; Bishop, John G.

2015-01-01

Invasive planktonic crustaceans have become a prominent feature of aquatic communities worldwide, yet their effects on food webs are not well known. The Asian calanoid copepod, Pseudodiaptomus forbesi, introduced to the Columbia River Estuary approximately 15 years ago, now dominates the late-summer zooplankton community, but its use by native aquatic predators is unknown. We investigated whether three species of planktivorous fishes (chinook salmon, three-spined stickleback, and northern pikeminnow) and one species of mysid exhibited higher feeding rates on native copepods and cladocerans relative to P. forbesi by conducting `single-prey’ feeding experiments and, additionally, examined selectivity for prey types with `two-prey’ feeding experiments. In single-prey experiments individual predator species showed no difference in feeding rates on native cyclopoid copepods (Cyclopidae spp.) relative to invasive P. forbesi, though wild-collected predators exhibited higher feeding rates on cyclopoids when considered in aggregate. In two-prey experiments, chinook salmon and northern pikeminnow both strongly selected native cladocerans (Daphnia retrocurva) over P. forbesi, and moreover, northern pikeminnow selected native Cyclopidae spp. over P. forbesi. On the other hand, in two-prey experiments, chinook salmon, three-spined stickleback and mysids were non- selective with respect to feeding on native cyclopoid copepods versus P. forbesi. Our results indicate that all four native predators in the Columbia River Estuary can consume the invasive copepod, P. forbesi, but that some predators select for native zooplankton over P. forbesi, most likely due to one (or both) of two possible underlying casual mechanisms: 1) differential taxon-specific prey motility and escape responses (calanoids > cyclopoids > daphnids) or 2) the invasive status of the zooplankton prey resulting in naivety, and thus lower feeding rates, of native predators feeding on invasive prey. PMID:26618851

Native American Adult Reader III.

ERIC Educational Resources Information Center

King, Lovern Root, Ed.

This reader, one of three designed to provide adults in basic education/GED programs with meaningful material based on Native American cultures, includes selections appropriate for advanced reading ability (grade 7 and above). The twelve readings focus on culture, history, and contemporary concerns of Native Americans. Each selection includes a…

Conjuring the Colonizer: Alternative Readings of Magic Realism in Sherman Alexie's "Reservation Blues"

ERIC Educational Resources Information Center

Belcher, Wendy

2007-01-01

Sherman Alexie's "Reservation Blues" has inspired both admiration and castigation. Critics such as Stephen Evans, Adrian C. Louis, Joseph Coulombe, and James Cox have praised Alexie's satiric upending of stereotypes about Native Americans, claiming that Alexie's work "uses stereotypes...of the...Indian, in new and entirely moral and ethical ways."…

Indian and Northern Affairs Annual Report, 1976-1977. Affaires Indiennes et du Nord Rapport Annuel, 1976-1977.

ERIC Educational Resources Information Center

Department of Indian Affairs and Northern Development, Ottawa (Ontario).

The report presents information on Indian and northern affairs in the areas of education, economics, Native claims, social and cultural development, conservation, and community development. Discussed are the Parks Canada Program which preserves Canada's natural and human heritage by means of national and historic parks and sites, and conservation…

A Review on Application of Computers in Education inside and outside of Iran

ERIC Educational Resources Information Center

Mahboudi, Hamid Reza; Farrokhi, Farahman; Ansarin, Ali Akbar

2017-01-01

This paper first presents an overview of the Digital Natives claim made by Prensky (2001) and its characteristics. Secondly, focusing on the Iranian context, the paper examines the reports of UNESCO Institute for Statistics (UIS, 2014), the present state of ICT integration in education in national research, and the present state of ICT integration…

Nutrition labelling, marketing techniques, nutrition claims and health claims on chip and biscuit packages from sixteen countries.

PubMed

Mayhew, Alexandra J; Lock, Karen; Kelishadi, Roya; Swaminathan, Sumathi; Marcilio, Claudia S; Iqbal, Romaina; Dehghan, Mahshid; Yusuf, Salim; Chow, Clara K

2016-04-01

Food packages were objectively assessed to explore differences in nutrition labelling, selected promotional marketing techniques and health and nutrition claims between countries, in comparison to national regulations. Cross-sectional. Chip and sweet biscuit packages were collected from sixteen countries at different levels of economic development in the EPOCH (Environmental Profile of a Community's Health) study between 2008 and 2010. Seven hundred and thirty-seven food packages were systematically evaluated for nutrition labelling, selected promotional marketing techniques relevant to nutrition and health, and health and nutrition claims. We compared pack labelling in countries with labelling regulations, with voluntary regulations and no regulations. Overall 86 % of the packages had nutrition labels, 30 % had health or nutrition claims and 87 % displayed selected marketing techniques. On average, each package displayed two marketing techniques and one health or nutrition claim. In countries with mandatory nutrition labelling a greater proportion of packages displayed nutrition labels, had more of the seven required nutrients present, more total nutrients listed and higher readability compared with those with voluntary or no regulations. Countries with no health or nutrition claim regulations had fewer claims per package compared with countries with regulations. Nutrition label regulations were associated with increased prevalence and quality of nutrition labels. Health and nutrition claim regulations were unexpectedly associated with increased use of claims, suggesting that current regulations may not have the desired effect of protecting consumers. Of concern, lack of regulation was associated with increased promotional marketing techniques directed at children and misleadingly promoting broad concepts of health.

32 CFR 1645.7 - Evaluation of claim.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Evaluation of claim. 1645.7 Section 1645.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.7 Evaluation of claim. (a) In evaluating a claim for classification in Class 4...

32 CFR 1645.7 - Evaluation of claim.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Evaluation of claim. 1645.7 Section 1645.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.7 Evaluation of claim. (a) In evaluating a claim for classification in Class 4...

32 CFR 1645.7 - Evaluation of claim.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Evaluation of claim. 1645.7 Section 1645.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.7 Evaluation of claim. (a) In evaluating a claim for classification in Class 4...

32 CFR 1645.7 - Evaluation of claim.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Evaluation of claim. 1645.7 Section 1645.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.7 Evaluation of claim. (a) In evaluating a claim for classification in Class 4...

32 CFR 1645.7 - Evaluation of claim.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Evaluation of claim. 1645.7 Section 1645.7 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.7 Evaluation of claim. (a) In evaluating a claim for classification in Class 4...

Legal action against health claims on foods and beverages marketed to youth.

PubMed

Rutkow, Lainie; Vernick, Jon S; Edwards, Danielle M; Rodman, Sarah O; Barry, Colleen L

2015-03-01

The prevalence of obesity among US children raises numerous health concerns. One pathway to reduce childhood obesity is by decreasing energy intake through the ingestion of fewer calories. Yet, food and beverage manufacturers often promote energy-dense items for children via varied health claims. Deceptive health claims are prohibited, and may be addressed through litigation or governmental regulatory efforts. While the amount of legal action against these potentially deceptive claims has increased, no comprehensive assessment has been conducted. This article, which analyzes litigation and governmental regulatory activities, considers key factors that may influence decisions to take legal action against potentially deceptive health claims on foods and beverages, including scientific support, forum selection, selection of plaintiffs, and potential public health impact.

Legal Action Against Health Claims on Foods and Beverages Marketed to Youth

PubMed Central

Vernick, Jon S.; Edwards, Danielle M.; Rodman, Sarah O.; Barry, Colleen L.

2015-01-01

The prevalence of obesity among US children raises numerous health concerns. One pathway to reduce childhood obesity is by decreasing energy intake through the ingestion of fewer calories. Yet, food and beverage manufacturers often promote energy-dense items for children via varied health claims. Deceptive health claims are prohibited, and may be addressed through litigation or governmental regulatory efforts. While the amount of legal action against these potentially deceptive claims has increased, no comprehensive assessment has been conducted. This article, which analyzes litigation and governmental regulatory activities, considers key factors that may influence decisions to take legal action against potentially deceptive health claims on foods and beverages, including scientific support, forum selection, selection of plaintiffs, and potential public health impact. PMID:25602904

Internet cigarette sales and Native American sovereignty: political and public health contexts.

PubMed

Samuel, Kari A; Ribisl, Kurt M; Williams, Rebecca S

2012-05-01

Internet cigarette vendors (ICVs) advertise low prices for tobacco products, subverting public health policy efforts to curtail smoking by raising prices. Many online retailers in the United States claim affiliation with Native American tribes and share in tribal tax-free status. Sales of discounted cigarettes from both online vendors and brick-and-mortar stores have angered non-Native retailers and triggered enforcement actions by state and federal governments in the United States concerned over lost cigarette excise tax revenue. Examination of the history and politics of cigarette sales on reservations and attempts to regulate Internet cigarette sales highlights the potential role for greater use of negotiated intergovernmental agreements to address reservation-based tobacco sales. Our review notes global parallels and explicates history and politics of such regulation in the United States, and offers background for collaborative efforts to regulate tobacco sales and decrease tobacco use.

Black Immigrants and Black Natives Attending Selective Colleges and Universities in the United States

ERIC Educational Resources Information Center

Massey, Douglas S.; Mooney, Margarita; Torres, Kimberly C.; Charles, Camille Z.

2007-01-01

This analysis uses data from the National Longitudinal Survey of Freshmen (NLSF) to study black immigrants and natives attending selective colleges and universities in the United States. In the NLSF, 747 black students were of native origin, and 281 were of immigrant origin, yielding an overall immigrant percentage of 27 percent. The…

Very Special Natives: The Evolving Role of Teachers as Informants in Educational Ethnography.

ERIC Educational Resources Information Center

Florio, Susan

Underlying the current use of ethnography in the study of teaching and learning is the assumption of an analogy between the school or classroom and culture. The claim of educational ethnography is that it discovers and describes the ways that members of the school community create and share meaning. Ethnographers aim to discover the operating…

Recognising English Accents in the Community: Omani Students' Accent Preferences and Perceptions of Nativeness

ERIC Educational Resources Information Center

Buckingham, Louisa

2015-01-01

Previous research has revealed that although EFL students may claim to prefer British/US accents they often have difficulty identifying them, especially when such accents may differ from "standard" accents presented in ELT materials. In the Gulf, English is widely used as a lingua franca or as a second language by the large expatriate…

We Are the New Nation (Nous Sommes La Nouvelle Nation). The Metis and National Native Policy.

ERIC Educational Resources Information Center

Daniels, Harry W.

A compilation of six policy statements, the booklet is intended to draw attention to the suppression of the rights of indigenous peoples (specifically, the Canadian Metis) by an inflexible federalist system of government, misguided national policies, and land claim settlements such as the 1978 COPE settlement. It is also intended to propose…

Shades of Cosmopolitanism: EFL Teachers' Perspectives on English Accents and Pronunciation Teaching in the Gulf

ERIC Educational Resources Information Center

Buckingham, Louisa

2015-01-01

Research suggests that passing for a native English speaker (NES) is often perceived as desirable by teachers of English as a Foreign Language (EFL) and employers, and students may claim to prefer certain NES accents as learning models. While this may be partly motivated by the prevalence of a particular regional accent in ESL contexts or…

Perception of intelligibility and qualities of non-native accented speakers.

PubMed

Fuse, Akiko; Navichkova, Yuliya; Alloggio, Krysteena

To provide effective treatment to clients, speech-language pathologists must be understood, and be perceived to demonstrate the personal qualities necessary for therapeutic practice (e.g., resourcefulness and empathy). One factor that could interfere with the listener's perception of non-native speech is the speaker's accent. The current study explored the relationship between how accurately listeners could understand non-native speech and their perceptions of personal attributes of the speaker. Additionally, this study investigated how listeners' familiarity and experience with other languages may influence their perceptions of non-native accented speech. Through an online survey, native monolingual and bilingual English listeners rated four non-native accents (i.e., Spanish, Chinese, Russian, and Indian) on perceived intelligibility and perceived personal qualities (i.e., professionalism, intelligence, resourcefulness, empathy, and patience) necessary for speech-language pathologists. The results indicated significant relationships between the perception of intelligibility and the perception of personal qualities (i.e., professionalism, intelligence, and resourcefulness) attributed to non-native speakers. However, these findings were not supported for the Chinese accent. Bilingual listeners judged the non-native speech as more intelligible in comparison to monolingual listeners. No significant differences were found in the ratings between bilingual listeners who share the same language background as the speaker and other bilingual listeners. Based on the current findings, greater perception of intelligibility was the key to promoting a positive perception of personal qualities such as professionalism, intelligence, and resourcefulness, important for speech-language pathologists. The current study found evidence to support the claim that bilinguals have a greater ability in understanding non-native accented speech compared to monolingual listeners. The results, however, did not confirm an advantage for bilingual listeners sharing the same language backgrounds with the non-native speaker over other bilingual listeners. Copyright © 2017 Elsevier Inc. All rights reserved.

An invasive plant alters phenotypic selection on the vegetative growth of a native congener.

PubMed

Beans, Carolyn M; Roach, Deborah A

2015-02-01

The ecological consequences of plant competition have frequently been tested, but the evolutionary outcomes of these interactions have gone largely unexplored. The study of species invasions can make an important contribution to this field of research by allowing us to watch ecological and evolutionary processes unfold as a novel species is integrated into a plant community. We explored the ecological and evolutionary impact of an invasive jewelweed, Impatiens glandulifera, on a closely related native congener, I. capensis and asked: (1) Does the presence of the invasive jewelweed alter the fitness of native jewelweed populations? (2) Does the invasive jewelweed affect the vegetative growth of the native congener? and (3) Does the invasive jewelweed alter phenotypic selection on the vegetative traits of the native congener? We used a greenhouse competition experiment, an invasive species removal field experiment, and a survey of natural populations. We show that when the invasive jewelweed is present, phenotypic selection favors native jewelweed individuals investing less in rapid upward growth and more in branching and fruiting potential through the production of nodes. This research demonstrates that invasive plants have the potential to greatly alter natural selection on native competitors. Studies investigating altered selection in invaded communities can reveal the potential evolutionary impact of invasive competitors, while deepening our understanding of the more general role of competition in driving plant evolution and permitting species coexistence. © 2015 Botanical Society of America, Inc.

The Function of Native American Storytelling as Means of Education in Luci Tapahonso's Selected Poems

ERIC Educational Resources Information Center

Saddam, Widad Allawi; Ya, Wan Roselezam Wan

2015-01-01

Native American storytelling has become a very vital issue in education. It preserves Native American history for the next generation and teaches them important lessons about the Native American culture. It also conveys moral meanings, knowledge and social values of the Native American people to the universe. More importantly, Native American…

Where do inmmigrants fare worse? Modeling workplace wage gap variation with longitudinal employer-employee data.

PubMed

Tomaskovic-Devey, Donald; Hällsten, Martin; Avent-Holt, Dustin

2015-01-01

The authors propose a strategy for observing and explaining workplace variance in categorically linked inequalities. Using Swedish economy-wide linked employer-employee panel data, the authors examine variation in workplace wage inequalities between native Swedes and non-Western immigrants. Consistent with relational inequality theory, the authors' findings are that immigrant-native wage gaps vary dramatically across workplaces, even net of strong human capital controls. The authors also find that, net of observed and fixed-effect controls for individual traits, workplace immigrant-native wage gaps decline with increased workplace immigrant employment and managerial representation and increase when job segregation rises. These results are stronger in high-inequality workplaces and for white-collar employees: contexts in which one expects status-based claims on organizational resources, the central causal mechanism identified by relational inequality theory, to be stronger. The authors conclude that workplace variation in the non-Western immigrant-native wage gaps is contingent on organizational variationin the relative power of groups and the institutional context in which that power is exercised.

43 CFR 2091.9-1 - Alaska Native selections.

Code of Federal Regulations, 2011 CFR

2011-10-01

... MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) SPECIAL LAWS AND RULES Segregation and Opening of Lands § 2091.9-1 Alaska Native selections. The segregation and opening of lands authorized for...

Elevated CO₂ does not offset greater water stress predicted under climate change for native and exotic riparian plants.

PubMed

Perry, Laura G; Shafroth, Patrick B; Blumenthal, Dana M; Morgan, Jack A; LeCain, Daniel R

2013-01-01

In semiarid western North American riparian ecosystems, increased drought and lower streamflows under climate change may reduce plant growth and recruitment, and favor drought-tolerant exotic species over mesic native species. We tested whether elevated atmospheric CO₂ might ameliorate these effects by improving plant water-use efficiency. We examined the effects of CO₂ and water availability on seedlings of two native (Populus deltoides spp. monilifera, Salix exigua) and three exotic (Elaeagnus angustifolia, Tamarix spp., Ulmus pumila) western North American riparian species in a CO₂-controlled glasshouse, using 1-m-deep pots with different water-table decline rates. Low water availability reduced seedling biomass by 70-97%, and hindered the native species more than the exotics. Elevated CO₂ increased biomass by 15%, with similar effects on natives and exotics. Elevated CO₂ increased intrinsic water-use efficiency (Δ¹³C(leaf) ), but did not increase biomass more in drier treatments than wetter treatments. The moderate positive effects of elevated CO₂ on riparian seedlings are unlikely to counteract the large negative effects of increased aridity projected under climate change. Our results suggest that increased aridity will reduce riparian seedling growth despite elevated CO₂, and will reduce growth more for native Salix and Populus than for drought-tolerant exotic species. No claim to original US government works. New Phytologist © 2012 New Phytologist Trust.

Neocolonialism and Contested Spiritual Landscapes in Modern American Astronomy

NASA Astrophysics Data System (ADS)

Swanner, L.

2017-12-01

In the second half of the twentieth century, Native American and Native Hawaiian activists clashed with the American astronomy community over telescope construction on sacred mountains. Multimillion dollar observatory projects planned for the Native Hawaiian sacred peak of Maunakea and the Native American sacred mountains of Kitt Peak and Mt. Graham in Arizona were stalled or abandoned following dramatic protests and legal disputes at each observatory site. Situating these controversies within the history of emerging Native rights movements in the United States, I argue that cultural gaps between pro- and anti-observatory groups are an artifact of what I shall call "neocolonialist science." Neocolonialist science, the domination and exploitation of Native lands by an occupying force for the purpose of practicing science, is also defined by the failure to acknowledge the impact of past and present conquests of Native land and cultural oppression. Despite astronomers' well-meaning attempts to demonstrate cultural sensitivity, the perception of telescopes as instruments of conquest has haunted each new observatory project. While astronomers typically see little connection between colonialism and the pursuit of knowledge, Native activists often see little distinction. Retained in inter-generational memory through oral tradition, the wounds of colonization remain fresh, and construction of telescopes on Native lands is often perceived as the latest attack on culture and sovereignty. These telescope controversies reveal that Big Science is surprisingly vulnerable to grassroots opposition, since religious claims on the mountain summits have severely restricted scientific development. To narrow the ideological divide between scientific and spiritual understandings of land use, I conclude that the future of science on sacred lands critically depends on acknowledging the colonialist past.

Where to Look for American Sign Language (ASL) Sublexical Structure in the Visual World: Reply to Salverda (2016)

ERIC Educational Resources Information Center

Lieberman, Amy M.; Borovsky, Arielle; Hatrak, Marla; Mayberry, Rachel I.

2016-01-01

In this reply to Salverda (2016), we address a critique of the claims made in our recent study of real-time processing of American Sign Language (ASL) signs using a novel visual world eye-tracking paradigm (Lieberman, Borovsky, Hatrak, & Mayberry, 2015). Salverda asserts that our data do not support our conclusion that native signers and…

The Indirect Empathic Approach to Claim Letters.

ERIC Educational Resources Information Center

Bell, James D.

1985-01-01

In discussing letter-writing methods for business communication classes, the article explains that claim letter formats other than the direct approach are not only legitimate, but also effective, and suggests that the approach selected should depend upon the circumstances surrounding the claim. (CT)

An update on the prevalence and incidence of epilepsy among older adults.

PubMed

Ip, Queeny; Malone, Daniel C; Chong, Jenny; Harris, Robin B; Labiner, David M

2018-01-01

To estimate the prevalence and incidence of epilepsy among beneficiaries of Arizona Medicare aged 65 and over. An analysis of Medicare administrative claims data for 2009-2011 for the State of Arizona was conducted. Epilepsy was defined as a beneficiary who had either≥one claim with diagnostic code of 345.xx (epilepsy) or at least two claims with diagnosis code of 780.3x (seizure) ≥30days apart. Stroke-related and psychiatric comorbidities were determined by diagnostic codes. Average annual prevalence and incidence were calculated and stratified by demographic characteristics and comorbidities. Odds ratios (OR) and 95% confidence intervals (CI) were calculated as measures of effect for prevalence and incidence and the chi-square statistic was calculated to compare the proportions of epilepsy cases with and without comorbidities (alpha=0.05). The overall average annual prevalence and incidence over the study period was 15.2/1000 and 6.1/1000, respectively. Relative to the 65-69 age group and White beneficiaries, the highest prevalence was observed for beneficiaries 85 years or older (19.8/1000, OR 1.66, 95% CI 1.53-1.81) and Native Americans (21.2/1000, OR 1.42, 95% CI 1.25-1.62). In contrast, the highest incidence rates were observed for beneficiaries 85 years and older (8.5/1000, OR 1.82, 95% CI 1.60-2.07) and for Black beneficiaries (8.7/1000, OR 1.44, 95% CI 1.12-1.86). The incidence rate for Native Americans was not significantly different from that for White beneficiaries (6.2/1000, OR 1.02, 95% CI 0.81-1.29). More than one quarter of all cases (25.7%) and 31% of incident cases had either stroke-related and/or psychiatric comorbidities (all p-values < 0.001). Epilepsy is a significant neurological disease among Medicare beneficiaries 65 years and older. Beneficiaries aged 85 and older and Black and Native Americans experienced higher rates of epilepsy than other demographic subgroups compared to White beneficiaries. Copyright © 2017 Elsevier B.V. All rights reserved.

A History and Case Study at a Selected Tribal College

ERIC Educational Resources Information Center

Oltrogge, Micheal P.

2010-01-01

"A History and Case Study at a Selected Tribal College" focuses on a tribally chartered two-year institution of higher education. The selected Tribal College serves Native American and non-Native American populations on two separate and distinct reservations and one urban location. This study surveys the history to answer basic foundational and…

Fusarium graminearum: pathogen or endophyte of North American grasses?

PubMed

Lofgren, Lotus A; LeBlanc, Nicholas R; Certano, Amanda K; Nachtigall, Jonny; LaBine, Kathryn M; Riddle, Jakob; Broz, Karen; Dong, Yanhong; Bethan, Bianca; Kafer, Christopher W; Kistler, H Corby

2018-02-01

Mycotoxin-producing Fusarium graminearum and related species cause Fusarium head blight on cultivated grasses, such as wheat and barley. However, these Fusarium species may have had a longer evolutionary history with North American grasses than with cultivated crops and may interact with the ancestral hosts in ways which are biochemically distinct. We assayed 25 species of asymptomatic native grasses for the presence of Fusarium species and confirmed infected grasses as hosts using re-inoculation tests. We examined seed from native grasses for the presence of mycotoxin-producing Fusarium species and evaluated the ability of these fungi to produce mycotoxins in both native grass and wheat hosts using biochemical analysis. Mycotoxin-producing Fusarium species were shown to be prevalent in phylogenetically diverse native grasses, colonizing multiple tissue types, including seeds, leaves and inflorescence structures. Artificially inoculated grasses accumulated trichothecenes to a much lesser extent than wheat, and naturally infected grasses showed little to no accumulation. Native North American grasses are commonly inhabited by Fusarium species, but appear to accommodate these toxigenic fungi differently from cultivated crops. This finding highlights how host identity and evolutionary history may influence the outcome of plant-fungal interactions and may inform future efforts in crop improvement. No claim to original US Government works. New Phytologist © 2017 New Phytologist Trust.

Using Self-reports or Claims to Assess Disease Prevalence: It's Complicated.

PubMed

St Clair, Patricia; Gaudette, Étienne; Zhao, Henu; Tysinger, Bryan; Seyedin, Roxanna; Goldman, Dana P

2017-08-01

Two common ways of measuring disease prevalence include: (1) using self-reported disease diagnosis from survey responses; and (2) using disease-specific diagnosis codes found in administrative data. Because they do not suffer from self-report biases, claims are often assumed to be more objective. However, it is not clear that claims always produce better prevalence estimates. Conduct an assessment of discrepancies between self-report and claims-based measures for 2 diseases in the US elderly to investigate definition, selection, and measurement error issues which may help explain divergence between claims and self-report estimates of prevalence. Self-reported data from 3 sources are included: the Health and Retirement Study, the Medicare Current Beneficiary Survey, and the National Health and Nutrition Examination Survey. Claims-based disease measurements are provided from Medicare claims linked to Health and Retirement Study and Medicare Current Beneficiary Survey participants, comprehensive claims data from a 20% random sample of Medicare enrollees, and private health insurance claims from Humana Inc. Prevalence of diagnosed disease in the US elderly are computed and compared across sources. Two medical conditions are considered: diabetes and heart attack. Comparisons of diagnosed diabetes and heart attack prevalence show similar trends by source, but claims differ from self-reports with regard to levels. Selection into insurance plans, disease definitions, and the reference period used by algorithms are identified as sources contributing to differences. Claims and self-reports both have strengths and weaknesses, which researchers need to consider when interpreting estimates of prevalence from these 2 sources.

Dietary Supplements and Health Aids - A Critical Evaluation Part 2 - Macronutrients and Fiber.

ERIC Educational Resources Information Center

Dubick, Michael A.

1983-01-01

Part 1 of this evaluation of dietary supplements and health aids (SE 533 788) focused on various therapeutic claims made for vitamins and minerals. This part examines health-promoting claims made for selected macronutrients and fiber. Macronutrients examined include selected proteins, amino acids, enzymes, carbohydrates, and lipids. (JN)

Critical assessment of claims regarding management of feral cats by trap-neuter-return.

PubMed

Longcore, Travis; Rich, Catherine; Sullivan, Lauren M

2009-08-01

Many jurisdictions have adopted programs to manage feral cats by trap-neuter-return (TNR), in which cats are trapped and sterilized, then returned to the environment to be fed and cared for by volunteer caretakers. Most conservation biologists probably do not realize the extent and growth of this practice and that the goal of some leading TNR advocates is that cats ultimately be recognized and treated as "protected wildlife." We compared the arguments put forth in support of TNR by many feral cat advocates with the scientific literature. Advocates promoting TNR often claim that feral cats harm wildlife only on islands and not on continents; fill a natural or realized niche; do not contribute to the decline of native species; and are insignificant vectors or reservoirs of disease. Advocates also frequently make claims about the effectiveness of TNR, including claims that colonies of feral cats are eventually eliminated by TNR and that managed colonies resist invasion by other cats. The scientific literature contradicts each of these claims. TNR of feral cats is primarily viewed and regulated as an animal welfare issue, but it should be seen as an environmental issue, and decisions to implement it should receive formal environmental assessment. Conservation scientists have a role to play by conducting additional research on the effects of feral cats on wildlife and by communicating sound scientific information about this problem to policy makers.

32 CFR 1645.2 - The claim for minister of religion classification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false The claim for minister of religion classification. 1645.2 Section 1645.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.2 The claim for minister of religion...

32 CFR 1645.2 - The claim for minister of religion classification.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false The claim for minister of religion classification. 1645.2 Section 1645.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.2 The claim for minister of religion...

32 CFR 1645.2 - The claim for minister of religion classification.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false The claim for minister of religion classification. 1645.2 Section 1645.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.2 The claim for minister of religion...

32 CFR 1645.2 - The claim for minister of religion classification.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false The claim for minister of religion classification. 1645.2 Section 1645.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.2 The claim for minister of religion...

32 CFR 1645.2 - The claim for minister of religion classification.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false The claim for minister of religion classification. 1645.2 Section 1645.2 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.2 The claim for minister of religion...

Design and Implementation of a 3D Multi-User Virtual World for Language Learning

ERIC Educational Resources Information Center

Ibanez, Maria Blanca; Garcia, Jose Jesus; Galan, Sergio; Maroto, David; Morillo, Diego; Kloos, Carlos Delgado

2011-01-01

The best way to learn is by having a good teacher and the best language learning takes place when the learner is immersed in an environment where the language is natively spoken. 3D multi-user virtual worlds have been claimed to be useful for learning, and the field of exploiting them for education is becoming more and more active thanks to the…

Federal repatriation legislation and the role of physical anthropology in repatriation.

PubMed

Ousley, Stephen D; Billeck, William T; Hollinger, R Eric

2005-01-01

Two laws governing the disposition of Native American human remains in museums and institutions have had a profound impact on anthropology, and especially physical anthropology. In contrast to the perception of constant conflict between Native Americans and physical anthropologists, the repatriation process based on these laws has been in large part harmonious between institutions and Native peoples in the US. Despite misconceptions, the Native American Graves Protection and Repatriation Act (NAPGRA; 25 United States Code (U.S.C.) 3001-3013) was not intended to halt further research on Native American remains in museums. In fact, court decisions have affirmed that the documentation of human remains produces information no other methods can provide, and provides necessary evidence to be incorporated and weighed, along with other evidence, in evaluating "cultural affiliation," the legal term for the required connection from federally recognized Native American groups to their ancestors. The wide variety of osteological data collected at the National Museum of Natural History (NMNH), Smithsonian Institution, have proven indispensable when evaluating cultural affiliation, especially when other information sources are unhelpful or ambiguous, and provide an empirical basis for determining the ancestry of individuals whose remains will be discovered in the future. To date, the claim-driven process at the NMNH has resulted in the affiliation and repatriation of more Native American remains than any other institution in the country. Repatriation experiences at the NMNH demonstrate the changing relationships between museums and Native peoples, the continuing important contributions that physical anthropology makes to the repatriation process, and the importance of physical anthropology in understanding the recent and ancient history of North America. (c) 2005 Wiley-Liss, Inc.

43 CFR 2650.4-7 - Public easements.

Code of Federal Regulations, 2014 CFR

2014-10-01

...-7 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) ALASKA NATIVE SELECTIONS Alaska Native Selections... all parties that participated in the development of the easement needs and information on major...

43 CFR 2650.4-7 - Public easements.

Code of Federal Regulations, 2013 CFR

2013-10-01

...-7 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) ALASKA NATIVE SELECTIONS Alaska Native Selections... all parties that participated in the development of the easement needs and information on major...

43 CFR 2650.4-7 - Public easements.

Code of Federal Regulations, 2012 CFR

2012-10-01

...-7 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND MANAGEMENT, DEPARTMENT OF THE INTERIOR LAND RESOURCE MANAGEMENT (2000) ALASKA NATIVE SELECTIONS Alaska Native Selections... all parties that participated in the development of the easement needs and information on major...

Plant compartment and biogeography affect microbiome composition in cultivated and native Agave species.

PubMed

Coleman-Derr, Devin; Desgarennes, Damaris; Fonseca-Garcia, Citlali; Gross, Stephen; Clingenpeel, Scott; Woyke, Tanja; North, Gretchen; Visel, Axel; Partida-Martinez, Laila P; Tringe, Susannah G

2016-01-01

Desert plants are hypothesized to survive the environmental stress inherent to these regions in part thanks to symbioses with microorganisms, and yet these microbial species, the communities they form, and the forces that influence them are poorly understood. Here we report the first comprehensive investigation of the microbial communities associated with species of Agave, which are native to semiarid and arid regions of Central and North America and are emerging as biofuel feedstocks. We examined prokaryotic and fungal communities in the rhizosphere, phyllosphere, leaf and root endosphere, as well as proximal and distal soil samples from cultivated and native agaves, through Illumina amplicon sequencing. Phylogenetic profiling revealed that the composition of prokaryotic communities was primarily determined by the plant compartment, whereas the composition of fungal communities was mainly influenced by the biogeography of the host species. Cultivated A. tequilana exhibited lower levels of prokaryotic diversity compared with native agaves, although no differences in microbial diversity were found in the endosphere. Agaves shared core prokaryotic and fungal taxa known to promote plant growth and confer tolerance to abiotic stress, which suggests common principles underpinning Agave-microbe interactions. No claim to US Government works. New Phytologist © 2015 New Phytologist Trust.

Ability Testing for Job Selection: Are the Economic Claims Justified?

ERIC Educational Resources Information Center

Levin, Henry M.

The use of ability testing for job selection has become widespread in the Federal Government and in the U.S. Employment Service, which assists private sector employers. The justification for the practice is based largely on research findings claiming a high level of validity for such tests in predicting job performance. More recently, such claims…

Important biological factors for utilizing native plant species

Treesearch

Loren E. Wiesner

1999-01-01

Native plant species are valuable resources for revegetation of disturbed ecosystems. The success of these plantings is dependent on the native species selected, quality of seed used, condition of the soil, environmental conditions before and after planting, planting equipment used, time of planting, and other factors. Most native species contain dormant seed. Dormancy...

SELECTING PLANT SPECIES FOR PESTICIDE REGISTRATION TESTS

EPA Science Inventory

Current test protocols used by the US EPA for the registration of pesticides examines plant responses of 10 crop species but may not examine regionally important native plants or crops. In order to test the efficiency of current test protocols we selected six native plant species...

32 CFR 536.12 - Commanding General, U.S. Army Medical Command.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 3 2011-07-01 2009-07-01 true Commanding General, U.S. Army Medical Command... AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.12 Commanding General, U.S. Army Medical Command. (a) After consulting with the Commander USARCS on the selection of medical claims...

32 CFR 536.12 - Commanding General, U.S. Army Medical Command.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 3 2012-07-01 2009-07-01 true Commanding General, U.S. Army Medical Command... AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.12 Commanding General, U.S. Army Medical Command. (a) After consulting with the Commander USARCS on the selection of medical claims...

32 CFR 536.12 - Commanding General, U.S. Army Medical Command.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 3 2014-07-01 2014-07-01 false Commanding General, U.S. Army Medical Command... AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.12 Commanding General, U.S. Army Medical Command. (a) After consulting with the Commander USARCS on the selection of medical claims...

32 CFR 536.12 - Commanding General, U.S. Army Medical Command.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 3 2010-07-01 2010-07-01 true Commanding General, U.S. Army Medical Command... AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.12 Commanding General, U.S. Army Medical Command. (a) After consulting with the Commander USARCS on the selection of medical claims...

32 CFR 536.12 - Commanding General, U.S. Army Medical Command.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 3 2013-07-01 2013-07-01 false Commanding General, U.S. Army Medical Command... AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.12 Commanding General, U.S. Army Medical Command. (a) After consulting with the Commander USARCS on the selection of medical claims...

32 CFR 1639.2 - The claim for Class 2-D.

Code of Federal Regulations, 2011 CFR

2011-07-01

... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF REGISTRANTS PREPARING FOR THE MINISTRY § 1639.2 The claim for Class 2-D. A claim to classification in Class 2-D must be made by the registrant in writing, such document being placed in his file folder. ...

32 CFR 1639.2 - The claim for Class 2-D.

Code of Federal Regulations, 2010 CFR

2010-07-01

... National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF REGISTRANTS PREPARING FOR THE MINISTRY § 1639.2 The claim for Class 2-D. A claim to classification in Class 2-D must be made by the registrant in writing, such document being placed in his file folder. ...

An exotic invasive plant selects for increased competitive tolerance, but not competitive suppression, in a native grass.

PubMed

Fletcher, Rebecca A; Callaway, Ragan M; Atwater, Daniel Z

2016-06-01

Exotic invasive plants can exert strong selective pressure for increased competitive ability in native plants. There are two fundamental components of competitive ability: suppression and tolerance, and the current paradigm that these components have equal influences on a species' overall competitive ability has been recently questioned. If these components do not have equal influences on overall ability, then selection on competitive tolerance and suppression may be disproportionate. We used naturally invaded communities to study the effects of selection caused by an invasive forb, Centaurea stoebe, on a native grass, Pseudoroegneria spicata. P. spicata plants were harvested from within dense C. stoebe patches and from nearby uninvaded areas, divided clonally into replicates, then transplanted into a common garden where they grew alone or competed with C. stoebe. We found that P. spicata plants collected from within C. stoebe patches were significantly more tolerant of competition with C. stoebe than P. spicata plants collected from uninvaded areas, but plants from inside invaded patches were not superior at suppressing C. stoebe. These results are consistent with the hypothesis that strong competitors may select for tolerance to competition more than for the ability to suppress neighbors. This has important implications for how native plant communities may respond to invasion over time, and how invasive and native species may ultimately coexist.

Great Basin Native Plant Selection and Increase Project FY08 Progress Report

Treesearch

Nancy Shaw; Mike Pellant

2009-01-01

The Interagency Native Plant Materials Development Program (USDI and USDA 2002), USDI Bureau of Land Management programs and policies, and the Great Basin Restoration Initiative encourage the use of native species for rangeland rehabilitation and restoration where feasible. This project was initiated to foster the development of native plant materials for use in the...

DETERMINING POTENTIAL RISK TO NATIVE PLANTS FROM HERBICIDE DRIFT: COMPARATIVE RESPONSE OF SELECTED CROP AND NATIVE PLANT SPECIES TO GLYPHOSATE AND SULFOMETURON

EPA Science Inventory

abstract/abstract

While native plant communities may be at risk from herbicide use, current crop-centric test procedures for pesticide registration may not adequately represent the sensitivity of native non-crop plants to herbicides. We are designing a protocol to determi...

Planning, Development, and Change in Bristol Bay: A High School Curriculum. Teacher Guide and Student Text. Unit III: 1991 and Beyond. Unit IV: International Perspective. Revised.

ERIC Educational Resources Information Center

Lipka, Jerry; Willer, Cristy

Written with the broad goal of involving high school students in Bristol Bay, Alaska, in the planning and design of their region's future, this combined teacher guide and student text contains the third and fourth units of a seven-unit curriculum. Unit III covers the terms of the Alaska Native Claims Settlement Act and the complicated issues…

Evidence of Adverse Selection in Iranian Supplementary Health Insurance Market

PubMed Central

Mahdavi, Gh; Izadi, Z

2012-01-01

Background: Existence or non-existence of adverse selection in insurance market is one of the important cases that have always been considered by insurers. Adverse selection is one of the consequences of asymmetric information. Theory of adverse selection states that high-risk individuals demand the insurance service more than low risk individuals do. Methods: The presence of adverse selection in Iran’s supplementary health insurance market is tested in this paper. The study group consists of 420 practitioner individuals aged 20 to 59. We estimate two logistic regression models in order to determine the effect of individual’s characteristics on decision to purchase health insurance coverage and loss occurrence. Using the correlation between claim occurrence and decision to purchase health insurance, the adverse selection problem in Iranian supplementary health insurance market is examined. Results: Individuals with higher level of education and income level purchase less supplementary health insurance and make fewer claims than others make and there is positive correlation between claim occurrence and decision to purchase supplementary health insurance. Conclusion: Our findings prove the evidence of the presence of adverse selection in Iranian supplementary health insurance market. PMID:23113209

Selecting Native Arbuscular Mycorrhizal Fungi to Promote Cassava Growth and Increase Yield under Field Conditions

PubMed Central

Séry, D. Jean-Marc; Kouadjo, Z. G. Claude; Voko, B. R. Rodrigue; Zézé, Adolphe

2016-01-01

The use of arbuscular mycorrhizal fungal (AMF) inoculation in sustainable agriculture is now widespread worldwide. Although the use of inoculants consisting of native AMF is highly recommended as an alternative to commercial ones, there is no strategy to allow the selection of efficient fungal species from natural communities. The objective of this study was (i) to select efficient native AMF species (ii) evaluate their impact on nematode and water stresses, and (iii) evaluate their impact on cassava yield, an important food security crop in tropical and subtropical regions. Firstly, native AMF communities associated with cassava rhizospheres in fields were collected from different areas and 7 AMF species were selected, based upon their ubiquity and abundance. Using these criteria, two morphotypes (LBVM01 and LBVM02) out of the seven AMF species selected were persistently dominant when cassava was used as a trap plant. LBVM01 and LBVM02 were identified as Acaulospora colombiana (most abundant) and Ambispora appendicula, respectively, after phylogenetic analyses of LSU-ITS-SSU PCR amplified products. Secondly, the potential of these two native AMF species to promote growth and enhance tolerance to root-knot nematode and water stresses of cassava (Yavo variety) was evaluated using single and dual inoculation in greenhouse conditions. Of the two AMF species, it was shown that A. colombiana significantly improved the growth of the cassava and enhanced tolerance to water stress. However, both A. colombiana and A. appendicula conferred bioprotective effects to cassava plants against the nematode Meloidogyne spp., ranging from resistance (suppression or reduction of the nematode reproduction) or tolerance (low or no suppression in cassava growth). Thirdly, the potential of these selected native AMF to improve cassava growth and yield was evaluated under field conditions, compared to a commercial inoculant. In these conditions, the A. colombiana single inoculation and the dual inoculation significantly improved cassava yield compared to the commercial inoculant. This is the first report on native AMF species exhibiting multiple benefits for cassava crop productivity, namely improved plant growth and yield, water stress tolerance and nematode resistance. PMID:28066381

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pham, Grace H.; Rana, Ambar S. J. B.; Korkmaz, E. Nihal

Ubiquitin (Ub) chains regulate a wide range of biological processes, and Ub chain connectivity is a critical determinant of the many regulatory roles that this post-translational modification plays in cells. To understand how distinct Ub chains orchestrate different biochemical events, we and other investigators have developed enzymatic and non-enzymatic methods to synthesize Ub chains of well-defined length and connectivity. A number of chemical approaches have been used to generate Ub oligomers connected by non-native linkages; however, few studies have examined the extent to which non-native linkages recapitulate the structural and functional properties associated with native isopeptide bonds. Here, we comparemore » the structure and function of Ub dimers bearing native and non-native linkages. Using small-angle X-ray scattering (SAXS) analysis, we show that scattering profiles for the two types of dimers are similar. Moreover, using an experimental structural library and atomistic simulations to fit the experimental SAXS profiles, we find that the two types of Ub dimers can be matched to analogous structures. An important application of non-native Ub oligomers is to probe the activity and selectivity of deubiquitinases. Through steady-state kinetic analyses, we demonstrate that different families of deubiquitinases hydrolyze native and non-native isopeptide linkages with comparable efficiency and selectivity. Considering the significant challenges associated with building topologically diverse native Ub chains, our results illustrate that chains harboring non-native linkages can serve as surrogate substrates for explorations of Ub function.« less

The impact of modern migrations on present-day multi-ethnic Argentina as recorded on the mitochondrial DNA genome.

PubMed

Catelli, María Laura; Alvarez-Iglesias, Vanesa; Gómez-Carballa, Alberto; Mosquera-Miguel, Ana; Romanini, Carola; Borosky, Alicia; Amigo, Jorge; Carracedo, Angel; Vullo, Carlos; Salas, Antonio

2011-08-30

The genetic background of Argentineans is a mosaic of different continental ancestries. From colonial to present times, the genetic contribution of Europeans and sub-Saharan Africans has superposed to or replaced the indigenous genetic 'stratum'. A sample of 384 individuals representing different Argentinean provinces was collected and genotyped for the first and the second mitochondrial DNA (mtDNA) hypervariable regions, and selectively genotyped for mtDNA SNPs. This data was analyzed together with additional 440 profiles from rural and urban populations plus 304 from Native American Argentineans, all available from the literature. A worldwide database was used for phylogeographic inferences, inter-population comparisons, and admixture analysis. Samples identified as belonging to hg (hg) H2a5 were sequenced for the entire mtDNA genome. Phylogenetic and admixture analyses indicate that only half of the Native American component in urban Argentineans might be attributed to the legacy of extinct ancestral Argentineans and that the Spanish genetic contribution is slightly higher than the Italian one. Entire H2a5 genomes linked these Argentinean mtDNAs to the Basque Country and improved the phylogeny of this Basque autochthonous clade. The fingerprint of African slaves in urban Argentinean mtDNAs was low and it can be phylogeographically attributed predominantly to western African. The European component is significantly more prevalent in the Buenos Aires province, the main gate of entrance for Atlantic immigration to Argentina, while the Native American component is larger in North and South Argentina. AMOVA, Principal Component Analysis and hgs/haplotype patterns in Argentina revealed an important level of genetic sub-structure in the country. Studies aimed to compare mtDNA frequency profiles from different Argentinean geographical regions (e.g., forensic and case-control studies) should take into account the important genetic heterogeneity of the country in order to prevent false positive claims of association in disease studies or inadequate evaluation of forensic evidence.

The impact of modern migrations on present-day multi-ethnic Argentina as recorded on the mitochondrial DNA genome

PubMed Central

2011-01-01

Background The genetic background of Argentineans is a mosaic of different continental ancestries. From colonial to present times, the genetic contribution of Europeans and sub-Saharan Africans has superposed to or replaced the indigenous genetic 'stratum'. A sample of 384 individuals representing different Argentinean provinces was collected and genotyped for the first and the second mitochondrial DNA (mtDNA) hypervariable regions, and selectively genotyped for mtDNA SNPs. This data was analyzed together with additional 440 profiles from rural and urban populations plus 304 from Native American Argentineans, all available from the literature. A worldwide database was used for phylogeographic inferences, inter-population comparisons, and admixture analysis. Samples identified as belonging to hg (hg) H2a5 were sequenced for the entire mtDNA genome. Results Phylogenetic and admixture analyses indicate that only half of the Native American component in urban Argentineans might be attributed to the legacy of extinct ancestral Argentineans and that the Spanish genetic contribution is slightly higher than the Italian one. Entire H2a5 genomes linked these Argentinean mtDNAs to the Basque Country and improved the phylogeny of this Basque autochthonous clade. The fingerprint of African slaves in urban Argentinean mtDNAs was low and it can be phylogeographically attributed predominantly to western African. The European component is significantly more prevalent in the Buenos Aires province, the main gate of entrance for Atlantic immigration to Argentina, while the Native American component is larger in North and South Argentina. AMOVA, Principal Component Analysis and hgs/haplotype patterns in Argentina revealed an important level of genetic sub-structure in the country. Conclusions Studies aimed to compare mtDNA frequency profiles from different Argentinean geographical regions (e.g., forensic and case-control studies) should take into account the important genetic heterogeneity of the country in order to prevent false positive claims of association in disease studies or inadequate evaluation of forensic evidence. PMID:21878127

The Study of Cardiovascular Health Outcomes in the Era of Claims Data: The Cardiovascular Health Study

PubMed Central

Psaty, Bruce M; Delaney, Joseph A; Arnold, Alice M; Curtis, Lesley H; Fitzpatrick, Annette L; Heckbert, Susan R; McKnight, Barbara; Ives, Diane; Gottdiener, John S; Kuller, Lewis H; Longstreth, W T

2015-01-01

Background Increasingly, the diagnostic codes from administrative claims data are being used as clinical outcomes. Methods and Results Data from the Cardiovascular Health Study (CHS) were used to compare event rates and risk-factor associations between adjudicated hospitalized cardiovascular events and claims-based methods of defining events. The outcomes of myocardial infarction (MI), stroke, and heart failure (HF) were defined in three ways: 1) the CHS adjudicated event (CHS[adj]); 2) selected ICD9 diagnostic codes only in the primary position for Medicare claims data from the Center for Medicare and Medicaid Services (CMS[1st]); and 3) the same selected diagnostic codes in any position (CMS[any]). Conventional claims-based methods of defining events had high positive predictive values (PPVs) but low sensitivities. For instance, the PPV of an ICD9 code of 410.×1 for a new acute MI in the first position was 90.6%, but this code identified only 53.8% of incident MIs. The observed event rates were low. For MI, the incidence was 14.9 events per 1000 person years for CHS[adj] MI, 8.6 for CMS[1st] and 12.2 for CMS[any]. In general, CVD risk factor associations were similar across the three methods of defining events. Indeed, traditional CVD risk factors were also associated with all first hospitalizations not due to an MI. Conclusions The use of diagnostic codes from claims data as clinical events, especially when restricted to primary diagnoses, leads to an underestimation of event rates. Additionally, claims-based events data represent a composite endpoint that includes the outcome of interest and selected (misclassified) non-event hospitalizations. PMID:26538580

Study of Cardiovascular Health Outcomes in the Era of Claims Data: The Cardiovascular Health Study.

PubMed

Psaty, Bruce M; Delaney, Joseph A; Arnold, Alice M; Curtis, Lesley H; Fitzpatrick, Annette L; Heckbert, Susan R; McKnight, Barbara; Ives, Diane; Gottdiener, John S; Kuller, Lewis H; Longstreth, W T

2016-01-12

Increasingly, the diagnostic codes from administrative claims data are being used as clinical outcomes. Data from the Cardiovascular Health Study (CHS) were used to compare event rates and risk factor associations between adjudicated hospitalized cardiovascular events and claims-based methods of defining events. The outcomes of myocardial infarction (MI), stroke, and heart failure were defined in 3 ways: the CHS adjudicated event (CHS[adj]), selected International Classification of Diseases, Ninth Edition diagnostic codes only in the primary position for Medicare claims data from the Center for Medicare & Medicaid Services (CMS[1st]), and the same selected diagnostic codes in any position (CMS[any]). Conventional claims-based methods of defining events had high positive predictive values but low sensitivities. For instance, the positive predictive value of International Classification of Diseases, Ninth Edition code 410.x1 for a new acute MI in the first position was 90.6%, but this code identified only 53.8% of incident MIs. The observed event rates for CMS[1st] were low. For MI, the incidence was 14.9 events per 1000 person-years for CHS[adj] MI, 8.6 for CMS[1st] MI, and 12.2 for CMS[any] MI. In general, cardiovascular disease risk factor associations were similar across the 3 methods of defining events. Indeed, traditional cardiovascular disease risk factors were also associated with all first hospitalizations not resulting from an MI. The use of diagnostic codes from claims data as clinical events, especially when restricted to primary diagnoses, leads to an underestimation of event rates. Additionally, claims-based events data represent a composite end point that includes the outcome of interest and selected (misclassified) nonevent hospitalizations. © 2015 American Heart Association, Inc.

To select or to wait? The importance of criterion setting in debates of competitive lexical selection.

PubMed

Nozari, Nazbanou; Hepner, Christopher R

2018-06-05

Competitive accounts of lexical selection propose that the activation of competitors slows down the selection of the target. Non-competitive accounts, on the other hand, posit that target response latencies are independent of the activation of competing items. In this paper, we propose a signal detection framework for lexical selection and show how a flexible selection criterion affects claims of competitive selection. Specifically, we review evidence from neurotypical and brain-damaged speakers and demonstrate that task goals and the state of the production system determine whether a competitive or a non-competitive selection profile arises. We end by arguing that there is conclusive evidence for a flexible criterion in lexical selection, and that integrating criterion shifts into models of language production is critical for evaluating theoretical claims regarding (non-)competitive selection.

Mediterranean species of Caulerpa are polyploid with smaller genomes in the invasive ones.

PubMed

Varela-Álvarez, Elena; Gómez Garreta, Amelia; Rull Lluch, Jordi; Salvador Soler, Noemi; Serrao, Ester A; Siguán, María Antonia Ribera

2012-01-01

Caulerpa species are marine green algae, which often act as invasive species with rapid clonal proliferation when growing outside their native biogeographical borders. Despite many publications on the genetics and ecology of Caulerpa species, their life history and ploidy levels are still to be resolved and are the subject of large controversy. While some authors claimed that the thallus found in nature has a haplodiplobiontic life cycle with heteromorphic alternation of generations, other authors claimed a diploid or haploid life cycle with only one generation involved. DAPI-staining with image analysis and microspectrophotometry were used to estimate relative nuclear DNA contents in three species of Caulerpa from the Mediterranean, at individual, population and species levels. Results show that ploidy levels and genome size vary in these three Caulerpa species, with a reduction in genome size for the invasive ones. Caulerpa species in the Mediterranean are polyploids in different life history phases; all sampled C. taxifolia and C. racemosa var. cylindracea were in haplophasic phase, but in C. prolifera, the native species, individuals were found in both diplophasic and haplophasic phases. Different levels of endopolyploidy were found in both C. prolifera and C. racemosa var. cylindracea. Life history is elucidated for the Mediterranean C. prolifera and it is hypothesized that haplophasic dominance in C. racemosa var. cylindracea and C. taxifolia is a beneficial trait for their invasive strategies.

U.S. Geological Survey activities related to American Indians and Alaska Natives: Fiscal years 2007 and 2008

USGS Publications Warehouse

Marcus, Susan M.

2010-01-01

In the late 1800s, John Wesley Powell, the second director of the U.S. Geological Survey (USGS), followed his interest in the tribes of the Great Basin and Colorado Plateau and studied their cultures, languages, and surroundings. From that early time, the USGS has recognized the importance of Native knowledge and living in harmony with nature as complements to the USGS mission to better understand the Earth. Combining traditional ecological knowledge with empirical studies allows the USGS and Native American governments, organizations, and people to increase their mutual understanding and respect for this land. The USGS is the earth and natural science bureau within the U.S. Department of the Interior (DOI) and is not responsible for regulations or land management. Climate change is a major current issue affecting Native lives and traditions throughout the United States. Climate projections for the coming century indicate an increasing probability for more frequent and more severe droughts in the Southwest, including the Navajo Nation. Erosion has claimed Native homes in Alaska. Fish have become inedible due to diseases that turn their flesh mushy. Native people who rely on or who are culturally sustained by hunting, fishing, and using local plants are living with climate change now. The traditional knowledge of Native peoples enriches and confirms the work of USGS scientists. The results are truly synergistic-greater than the sum of their parts. Traditional ecological knowledge is respected and increasingly used in USGS studies-when the holders of that knowledge choose to share it. The USGS respects the rights of Native people to maintain their patrimony of traditional ecological knowledge. The USGS studies can help Tribes, Native organizations, and natural resource professionals manage Native lands and resources with the best available unbiased data and information that can be added to their traditional knowledge. Wise Native leaders have noted that traditional ecological knowledge includes the connections between Earth and her denizens. From this perspective, it is the connections among these ?relatives? that needs to be nurtured. This perspective on nature is finding new adherents among Natives and non-Natives as understanding of climate change and other environmental conditions deepens. Although this report uses the term ?resources,? the USGS, through its interdisciplinary research, acknowledges the interconnectedness of the Earth and the things that live upon it.

[Use of nutrition marketing in products advertised on TV in Spain].

PubMed

Cuevas-Casado, I; Romero-Fernández, M M; Royo-Bordonada, M Á

2012-01-01

Nutrition marketing has generated a great amount of consumer interest; however, improper use of this type of marketing could mislead consumers. To describe the frequency and proper use in Spain of nutrition marketing for products advertised on television while analyzing their nutrient profile for comparison. Advertised food and drink products included in the study were selected after watching 80 hours of broadcasting of 4 Spanish television channels during May and June 2008. Upon purchase of the selected items, we estimated the frequency of use of the different nutrition marketing approaches, the proportion of nutritional and health claims meeting European regulations, and the proportion of less healthy products according to the United Kingdom Nutrient Profile Model UKNPM. Of the 88 products examined, 74% used nutrition marketing approaches. Half of the advertisements made nutrition claims and 42% health claims. The majority (89%) of the 83 nutrition claims met European regulations, with the category of "light products" being the least compliant with only 25% of products meeting regulations. Of the 37 product advertisements making health claims, 43% used authorized statements, of which, however, 75% also included unauthorized claims. Nutrient profile was less healthy in 55% of the products resorting to nutrition marketing. Lack of compliance with European regulations regarding nutrition and health claims, combined with the "less healthy" nutrient profile of many of the products marketed using these claims, may mislead Spanish consumers. To avoid this misinformation, it would be beneficial to: a) monitor level of adherence to regulations systematically; and b) introduce the use of nutrient profiles to approve these types of claims.

The role of habitat-selection in restricting invasive blue mussel advancement to protect native populations in San Francisco Bay

NASA Astrophysics Data System (ADS)

Mittal, N.; Saarman, N. P.; Pogson, G.

2013-12-01

Introduced species contribute to decline of biodiversity and ecosystem services. Introduced species threaten native species by increasing competition for space and resources, changing their habitat, and disrupting species interactions. Protecting native species is crucial to preserving ecosystem services (i.e. medicinal, agricultural, ecological, and cultural benefits) for future generations. In marine communities, the number of invasive species is dramatically increasing every year, further magnifying the negative impact on native species. This research determines if habitat-specific selection can protect native species from their invasive relatives, and could allow targeted habitat restoration for native species to maintain high levels of biodiversity. Blue mussels provide an ideal system for studying the impact of an invasive species (Mytilus galloprovincialis) on native mussels (M. trossulus), because M. galloprovincialis is marked as one of the world's 100 worst invasive species. Hybridization between M. galloprovincialis and M. trossulus occurs wherever their distributions overlap (i.e. Japan, Puget Sound, and central California). In central California, hybrids form in a broad variety of habitats ever since M. galloprovincialis was introduced about 100 years ago. The current level of threat posed to native mussels in central California is unknown. When population growth rate of an invasive species is higher than the native within a hybrid zone, the invader's genes become more prominent in the hybrids than the native species' genes. This uneven mix of genes and decrease of pure native mussels threatens to drive M. trossulus to extinction. Therefore, it is important to research which environment fosters highest success of pure native species. We conducted a field experiment in San Francisco Bay where mussels were reared in different habitats. We then collected samples and extracted DNA from each treatment, and genotyped them by a next-generation sequencing technique called 'RAD-tag' sequencing. We found that genotype distributions in the wild are consistent with habitat (e.g. temperature and salinity) playing a pivotal role in preventing the reproduction and hybridization between M. trossulus and M. galloprovincialis. We also found that growth and survival of invasive mussels was significantly affected by temperature and salinity conditions. These results support the hypothesis that habitat-specific selection can protect native mussels from their invasive relatives, and that targeted habitat restoration for native species could help conserve M. trossulus.

Risk adjustment model of credit life insurance using a genetic algorithm

NASA Astrophysics Data System (ADS)

Saputra, A.; Sukono; Rusyaman, E.

2018-03-01

In managing the risk of credit life insurance, insurance company should acknowledge the character of the risks to predict future losses. Risk characteristics can be learned in a claim distribution model. There are two standard approaches in designing the distribution model of claims over the insurance period i.e, collective risk model and individual risk model. In the collective risk model, the claim arises when risk occurs is called individual claim, accumulation of individual claim during a period of insurance is called an aggregate claim. The aggregate claim model may be formed by large model and a number of individual claims. How the measurement of insurance risk with the premium model approach and whether this approach is appropriate for estimating the potential losses occur in the future. In order to solve the problem Genetic Algorithm with Roulette Wheel Selection is used.

An Examination of Native and Immigrant Students' Social Networking Using the College Search and Selection Process

ERIC Educational Resources Information Center

Neimeyer, Bruce Carlton

2009-01-01

This dissertation explores the use of formal and informal networks through cyber- and traditional communication methods in the college search and selection process by native and immigrant students to examine various postulates and propositions of social capital theory. In addition, the analysis of cybernetworks used by disadvantaged, college bound…

Selecting plant species for ecological restoration: A perspective for land managers

Treesearch

Ray W. Brown; Michael C. Amacher

1999-01-01

We recommend in this paper that land managers adopt a policy of mandatory use of native plant species for revegetation and restoration of severe disturbances on wildlands throughout the Interior West. A review of the relative advantages and disadvantages of using introduced and native species suggests that selection criteria based on ecological adaptability and...

Does Hawaiian native forest conserve water? Lower uptake rates at tree and stand scale by Metrosideros polymorpha relative to plantation species

NASA Astrophysics Data System (ADS)

Kagawa, A. K.; Sack, L.; Duarte, T. K.; James, S. A.

2007-12-01

Native plants are often claimed to be conservative water users that enhance groundwater recharge compared to faster-growing non-native species that tend to dominate watersheds. This argument would have implications for motivating conservation and restoration of native forest in Hawai'i. However, few studies have examined differences in native and non-native plant transpiration (water use) at species or at stand level. Our aim was determine whether species matter to stand-level water use. We measured plant transpiration in a continuous mosaic of native forest and non-native tree plantation in Honaunau, Hawaii, focusing on endemic dominant tree Metrosideros polymorpha, alien timber trees Eucalyptus saligna and Fraxinus uhdei, and dominant understory Cibotium tree ferns. We measured xylem sap flow for six individuals of each species continuously for over eight weeks, and we estimated stand water use by scaling up these measurements using stand sapwood area and tree fern leaf area values obtained through vegetation surveys. Native forest dominant Metrosideros had the lowest rates of whole-tree daily water use at 8 kg day-1 (200kg m-2sapwood day-1), less than half the daily rates for Eucalyptus or Fraxinus; Metrosideros also had the lowest maximum transpiration rates of the three tree species. At the stand level, Fraxinus-dominated stands had higher water use than Eucalyptus- and Metrosideros- dominated stands due to the species' high sap flow rates, five-fold greater sapwood allocation, and the stands' two-fold greater dominant tree density. In Metrosideros-dominated stands, high Cibotium tree fern leaf area contributed to nearly 60% of water use, indicating the fern's critical role in forest water balance. Stand water use was influenced by factors at various scales, including species composition, stem density, tree sizes, and tree species' sapwood allocation, and was affected significantly by understory contributions. These findings highlight the importance of constituent species in forest water use, and in the case of this Hawaiian forest, indicate conservative water use by native forest.

Importance of Indigenous Breeds of Chicken for Rural Economy and Their Improvements for Higher Production Performance

PubMed Central

Padhi, Mahendra Kumar

2016-01-01

Indigenous/native breeds of chickens are playing an important role in rural economies in most of the developing and underdeveloped countries. They play a major role for the rural poor and marginalised section of the people with respect to their subsidiary income and also provide them with nutritious chicken egg and meat for their own consumption. Performance of native fowl can be improved by change in husbandry, feeding, and better health cover. However, genetic improvement may be made either through selection and crossbreeding or by utilisation of both selection and crossbreeding. Improvement through selection may be time consuming but the improvement will be permanent. Through crossbreeding improvement may be faster but research has to aim for the production of native-type birds with higher production potential. In the present review efforts have been made to present the importance of native fowl to rural economy and their improvement for higher production performance. PMID:27144053

Maternal smokeless tobacco use in Alaska Native women and singleton infant birth size.

PubMed

England, Lucinda J; Kim, Shin Y; Shapiro-Mendoza, Carrie K; Wilson, Hoyt G; Kendrick, Juliette S; Satten, Glen A; Lewis, Claire A; Whittern, Persenia; Tucker, Myra J; Callaghan, William M

2012-01-01

To examine the effects of maternal prenatal smokeless tobacco use on infant birth size. A retrospective medical record review of 502 randomly selected deliveries. Singleton deliveries to Alaska Native women residing in a defined geographical region in western Alaska, 1997-2005. A regional medical center's electronic records were used to identify singleton deliveries. Data on maternal tobacco exposure and pregnancy outcomes were abstracted from medical records. Logistic models were used to estimate adjusted mean birthweight, length and head circumference for deliveries to women who used no tobacco (n=121), used smokeless tobacco (n=237) or smoked cigarettes (n=59). Differences in mean birthweight, length and head circumference, 95% confidence intervals and p-values were calculated using non-users as the reference group. Infant birthweight, crown-heel length and head circumference. After adjustment for gestational age and other potential confounders, the mean birthweight of infants of smokeless tobacco users was reduced by 78 g compared with that of infants of non-users (p=0.18) and by 331 g in infants of smokers (p<0.01). No association was found between maternal smokeless tobacco use and infant length or infant head circumference. We found a modest but non-significant reduction in the birthweight of infants of smokeless tobacco users compared with infants of tobacco non-users. Because smokeless tobacco contains many toxic compounds that could affect other pregnancy outcomes, results of this study should not be construed to mean that smokeless tobacco use is safe during pregnancy. © 2011 Nordic Federation of Societies of Obstetrics and Gynecology No claim to original US government works.

Above- and below-ground effects of plant diversity depend on species origin: an experimental test with multiple invaders.

PubMed

Kuebbing, Sara E; Classen, Aimée T; Sanders, Nathan J; Simberloff, Daniel

2015-11-01

Although many plant communities are invaded by multiple nonnative species, we have limited information on how a species' origin affects ecosystem function. We tested how differences in species richness and origin affect productivity and seedling establishment. We created phylogenetically paired native and nonnative plant communities in a glasshouse experiment to test diversity-productivity relationships and responsible mechanisms (i.e. selection or complementarity effects). Additionally, we tested how productivity and associated mechanisms influenced seedling establishment. We used diversity-interaction models to describe how species' interactions influenced diversity-productivity relationships. Communities with more species had higher total biomass than did monoculture communities, but native and nonnative communities diverged in root : shoot ratios and the mechanism responsible for increased productivity: positive selection effect in nonnative communities and positive complementarity effect in native communities. Seedling establishment was 46% lower in nonnative than in native communities and was correlated with the average selection effect. Interspecific interactions contributed to productivity patterns, but the specific types of interactions differed between native and nonnative communities. These results reinforce findings that the diversity-productivity mechanisms in native and nonnative communities differ and are the first to show that these mechanisms can influence seedling establishment and that different types of interactions influence diversity-productivity relationships. © 2015 The Authors. New Phytologist © 2015 New Phytologist Trust.

Symbols of pride or prejudice? Examining the impact of Native American sports mascots on stereotype application.

PubMed

Burkley, Melissa; Burkley, Edward; Andrade, Angela; Bell, Angela C

2017-01-01

For over 50 years, a debate has existed over the use of Native American sports mascots; however, few empirical studies on the topic exist. The present study examined if supraliminal exposure to Native American mascots results in the application of negative stereotypes toward Native American people. Results indicated that the effect of Native American mascots was moderated by people's racial attitudes toward Native people. When exposed to Native mascots, people with a prejudiced attitude rated a Native American individual more stereotypically aggressive than those with a non-prejudiced attitude. However, this pattern did not occur when people were exposed to White mascots or neutral images. Furthermore, this pattern was not evident when people evaluated a non-Native individual. This overall pattern of results indicates that Native American mascots selectively facilitate the application of negative stereotypes, resulting in harmful evaluations of Native American people.

Decarboxylative alkylation for site-selective bioconjugation of native proteins via oxidation potentials.

PubMed

Bloom, Steven; Liu, Chun; Kölmel, Dominik K; Qiao, Jennifer X; Zhang, Yong; Poss, Michael A; Ewing, William R; MacMillan, David W C

2018-02-01

The advent of antibody-drug conjugates as pharmaceuticals has fuelled a need for reliable methods of site-selective protein modification that furnish homogeneous adducts. Although bioorthogonal methods that use engineered amino acids often provide an elegant solution to the question of selective functionalization, achieving homogeneity using native amino acids remains a challenge. Here, we explore visible-light-mediated single-electron transfer as a mechanism towards enabling site- and chemoselective bioconjugation. Specifically, we demonstrate the use of photoredox catalysis as a platform to selectivity wherein the discrepancy in oxidation potentials between internal versus C-terminal carboxylates can be exploited towards obtaining C-terminal functionalization exclusively. This oxidation potential-gated technology is amenable to endogenous peptides and has been successfully demonstrated on the protein insulin. As a fundamentally new approach to bioconjugation this methodology provides a blueprint toward the development of photoredox catalysis as a generic platform to target other redox-active side chains for native conjugation.

Decarboxylative alkylation for site-selective bioconjugation of native proteins via oxidation potentials

NASA Astrophysics Data System (ADS)

Bloom, Steven; Liu, Chun; Kölmel, Dominik K.; Qiao, Jennifer X.; Zhang, Yong; Poss, Michael A.; Ewing, William R.; MacMillan, David W. C.

2018-02-01

The advent of antibody-drug conjugates as pharmaceuticals has fuelled a need for reliable methods of site-selective protein modification that furnish homogeneous adducts. Although bioorthogonal methods that use engineered amino acids often provide an elegant solution to the question of selective functionalization, achieving homogeneity using native amino acids remains a challenge. Here, we explore visible-light-mediated single-electron transfer as a mechanism towards enabling site- and chemoselective bioconjugation. Specifically, we demonstrate the use of photoredox catalysis as a platform to selectivity wherein the discrepancy in oxidation potentials between internal versus C-terminal carboxylates can be exploited towards obtaining C-terminal functionalization exclusively. This oxidation potential-gated technology is amenable to endogenous peptides and has been successfully demonstrated on the protein insulin. As a fundamentally new approach to bioconjugation this methodology provides a blueprint toward the development of photoredox catalysis as a generic platform to target other redox-active side chains for native conjugation.

The Guide for Choosing Native American Parenting Curricula.

ERIC Educational Resources Information Center

Wingo, Robin R.; Mertensmeyer, Carol

This guide is designed to help professionals working with Native American parents to be better prepared to select culturally sensitive materials, to program more effectively, and to draw from the richness within the Native American culture. The guide is one in a series of culturally specific guides produced as part of ParentLink's Review of…

Reintroducing native plants to the American West

Treesearch

Derek J. Tilley

2007-01-01

The Aberdeen PMC is working together with other team members of the Great Basin Restoration Initiative (USDI-BLM) and the Great Basin Native Plant Selection and Increase Project (USDAFS) to develop techniques to increase native plant diversity in crested wheatgrass monocultures. Since the early 1930s crested wheatgrass has been used in range seedings in the...

Effect of loss control service on reported injury incidence.

PubMed

Nave, Michael E; Veltri, Anthony

2004-01-01

A retrospective analysis evaluated the effectiveness of an insurance carrier's flexible loss control service strategy in reducing workers' compensation policyholders' reported injury and illness claims. To assess the effects of a loss control service strategy on workers' compensation claim frequency rates, on medical-only claim rates, on severity-claim rates, and on claim cost among a group of California employers. Eighty-two small- and medium-sized companies with workers' compensation policies expiring in 1999 were randomly selected from a population of policyholders assigned to loss control consultants for two or more years. Claim performance data were obtained for each company's first expired in-force policy year and its 1999 expired policy year. The retrospective design was combined with a control component based on a randomly selected comparison group of 45 companies whose first policy year with the insurer expired in 1999 and who received safety services from the loss control staff. The flexible loss control consultation service strategy was associated with lower average claim rates and costs. Companies assigned to a loss control consultant for two or more years (the "outcome group") had an average claim rate of 1.24 per $10,000 premium, compared with a rate of 1.62 in the "initial group" and a rate of 1.60 in the "comparison group." The average severity-claim rate of the outcome group was 0.32, compared with the initial-year and comparison-group means of 0.48 and 0.46, respectively. The average medical-only claim rate was 0.92, compared with the initial- and comparison-group means of 1.14 and 1.14. The outcome group's average loss ratio was over 10% lower than that of the initial and comparison groups. Statistical analysis indicated that differences among the groups' claim rates and severity-claim rates were [F=(2,206) 4.938, P=0.008] and [F=(2,206) 8.208, P<0.001], respectively. A loss control service strategy that provides service flexibility and develops partnership between employer and consultant can help reduce the frequency and severity of workers' compensation claims. Barriers to consultation service flexibility, both internal and external, should be identified and removed to enhance service efficacy.

A Selected Annotated Bibliography of Material Relating to Racism, Blacks, Chicanos, Native Americans and Multi-Ethnicity. Vol. 4.

ERIC Educational Resources Information Center

Michigan Education Association, East Lansing. Div. of Minority Affairs.

Volume Four of this selected annotated bibliography is composed of the most recently discovered materials, pertaining to blacks, Latinos, Native Americans, multi-ethnicity and racism. Like the three previous annotated bibliographies, it is considered to reflect only that material which is held to be most representative and most relevant in terms…

From Native-Like Selections to English Academic Performance: Exploring the Knowledge Base of English Bilinguals

ERIC Educational Resources Information Center

Gomari, Hamid; Marshall, Dylan

2017-01-01

Pawley and Syder (1983) pointed out that idiomatic expressions can be discussed in terms of nativelike selection (NLS), which refers to the ability of the native speaker to express his/her intended meaning using an expression that is not only grammatical but also nativelike. In the current study, Pearson's correlation coefficients were used to…

A Selected Annotated Bibliography of Material Relating to Racism, Blacks, Chicanos, Native Americans and Multi-Ethnicity. Vol. 2.

ERIC Educational Resources Information Center

Michigan Education Association, East Lansing. Div. of Minority Affairs.

The second in the series, this selected annotated bibliography deals with new and recently discovered materials that address racism, Blacks, Chicanos, native Americans, and multi-ethnicity. This bibliography is considered to be not all inclusive but to reflect only on that material which is considered to be most representative of the realities…

A Selected Annotated Bibliography of Material Relating to Racism, Blacks, Chicanos, Native Americans and Multi-Ethnicity. Vol. 3.

ERIC Educational Resources Information Center

Michigan Education Association, East Lansing. Div. of Minority Affairs.

The third in the series, this selected annotated bibliography is composed of the most recently discovered materials pertaining to Blacks, Latinos, Native Americans, multi-ethnicity, and racism. It is said to reflect only that material considered most representative and most relevant in terms of the involvement and contributions that Third World…

Infants' Selectively Pay Attention to the Information They Receive from a Native Speaker of Their Language.

PubMed

Marno, Hanna; Guellai, Bahia; Vidal, Yamil; Franzoi, Julia; Nespor, Marina; Mehler, Jacques

2016-01-01

From the first moments of their life, infants show a preference for their native language, as well as toward speakers with whom they share the same language. This preference appears to have broad consequences in various domains later on, supporting group affiliations and collaborative actions in children. Here, we propose that infants' preference for native speakers of their language also serves a further purpose, specifically allowing them to efficiently acquire culture specific knowledge via social learning. By selectively attending to informants who are native speakers of their language and who probably also share the same cultural background with the infant, young learners can maximize the possibility to acquire cultural knowledge. To test whether infants would preferably attend the information they receive from a speaker of their native language, we familiarized 12-month-old infants with a native and a foreign speaker, and then presented them with movies where each of the speakers silently gazed toward unfamiliar objects. At test, infants' looking behavior to the two objects alone was measured. Results revealed that infants preferred to look longer at the object presented by the native speaker. Strikingly, the effect was replicated also with 5-month-old infants, indicating an early development of such preference. These findings provide evidence that young infants pay more attention to the information presented by a person with whom they share the same language. This selectivity can serve as a basis for efficient social learning by influencing how infants' allocate attention between potential sources of information in their environment.

Dissecting Practical Intelligence Theory: Its Claims and Evidence.

ERIC Educational Resources Information Center

Gottfredson, Linda S.

2003-01-01

The two key theoretical propositions of "Practical Intelligence in Everyday Life" are made plausible only if one ignores considerable evidence contradicting them. The six key empirical claims rest primarily on the illusion of evidence enhanced by selective reporting of results. (SLD)

Frugivore-Mediated Selection in A Habitat Transformation Scenario

PubMed Central

Fontúrbel, Francisco E.; Medel, Rodrigo

2017-01-01

Plant-animal interactions are strong drivers of phenotypic evolution. However, the extent to which anthropogenic habitat transformation creates new selective scenarios for plant-animal interactions is a little explored subject. We examined the effects of native forest replacement by exotic Eucalyptus trees on the frugivore-mediated phenotypic selection coefficients imposed by the relict marsupial Dromiciops gliroides upon traits involved in frugivore attraction and germination success of the mistletoe Tristerix corymbosus (Loranthaceae). We found significant gradients for seed weight and sugar content along the native - transformed habitat gradient. While selection for larger seed weight was more relevant in native habitats, fruits with intermediate sugar content were promoted in transformed habitats. The spatial habitat structure and microclimate features such as the degree of sunlight received influenced the natural selection processes, as they correlated with the phenotypic traits analysed. The response of this plant-frugivore interaction to human disturbance seemed to be context-dependent, in which extremely transformed habitats would offer new opportunities for natural selection on dispersal-related traits. Even in recent transformation events like this, human disturbance acts as a strong contemporary evolution driver. PMID:28349942

Walking ATMs and the immigration spillover effect: The link between Latino immigration and robbery victimization.

PubMed

Barranco, Raymond E; Shihadeh, Edward S

2015-07-01

Media reports and prior research suggest that undocumented Latino migrants are disproportionately robbed because they rely on a cash-only economy and they are reluctant to report crimes to law-enforcement (the Walking ATM phenomenon). From this we generate two specific research questions. First, we probe for an immigration spillover effect - defined as increased native and documented Latino robbery victimization due to offenders' inability to distinguish between the statuses of potential victims. Second, we examine the oft-repeated claim that Blacks robbers disproportionately target Latino victims. Using National Incident-Based Reporting System (NIBRS) data from 282 counties, results show (1) support for an immigration spillover effect but, (2) no support for the claim that Latinos are disproportionately singled out by Black robbers. We discuss the implications of our findings. Copyright © 2015 Elsevier Inc. All rights reserved.

Analysis of Taiwan patents for the medicinal mushroom "Niu-Chang- Chih".

PubMed

Chen, Yu-Fen; Lu, Wen-Ling; Wu, Ming-Der; Yuan, Gwo-Fang

2013-04-01

"Niu-Chang-Chih" (Antrodia cinnanomea) is a medicinal mushroom that has only been collected from the aromatic tree, Cinnamomum kanehirai, which is native to Taiwan. A total of 105 Taiwan patent applications and patents for "Niu-Chang-Chih" were collected and analyzed. Patent applications and granted patents claiming newly identified functional components from "Niu-Chang-Chih," biologically pure cultures of the mushroom strain, and cultivation of "Niu-Chang-Chih" were examined. Several applications and patents claim identified active compounds from "Niu-Chang- Chih," which provide better patent protection. These newly identified functional compounds include cyclohexanones, maleic and succinic acid derivatives, labdane diterpenoids, and benzenoids. Newly identified functional proteins include a glutathione-dependent formaldehyde dehydrogenase (GFD), a glycoprotein named ACA1, and a laccase. Newly identified functional polysaccharides include ACP1, ACP2, and ACP3. The number of patents for newly identified compounds and their uses are expected to continue growing.

Assessment of health claims, content, and safety of herbal supplements containing Ginkgo biloba

PubMed Central

Fransen, Heidi P.; Pelgrom, Sylvia M.G.J.; Stewart-Knox, Barbara; de Kaste, Dries; Verhagen, Hans

2010-01-01

Background European Regulation 1924/2006 states that all health claims made on foods need to be substantiated scientifically. Objective To apply the PASSCLAIM criteria for the scientific substantiation of health claims on foods to herbal supplements containing Ginkgo biloba. Evaluation of three selected claimed health effects for G. biloba (improvement of blood circulation, improvement of symptoms of old age, and improvement of memory) was achieved through review of publicly available scientific data. A total of 35 human intervention studies were evaluated. Commercially available products claimed to contain mainly G. biloba (N=29) were randomly sampled in the Netherlands and analyzed for their content on ginkgo extract. Also, a toxicological risk assessment was performed. Results The three selected health claims investigated could not be substantiated. This was mainly because of a lack of data from studies in healthy volunteers. In most studies results performed with a 24% standardized G. biloba extract were described. However, our chemical analysis showed that 25 of the 29 sampled products did not contain the required minimum 24% standardized extract. Moreover, in most preparations the content of substances typical for G. biloba did not conform to what was declared on the label. Since toxicity data for G. biloba are very limited, a safety limit could not be established. Conclusions Evidence is lacking for three health claims of herbal products with G. biloba. Neither safety nor efficacy can be guaranteed at the recommended daily dose. The multidisciplinary approach described in this paper provides good insight into issues that are relevant for the evaluation of health claims for herbal food supplements. PMID:20927202

Great Basin Native Plant Selection and Increase Project: FY2010 Progress Report

Treesearch

Nancy Shaw; Mike Pellant

2011-01-01

The Interagency Native Plant Materials Development Program outlined in the 2002 Report to Congress (USDI and USDA 2002), USDI Bureau of Land Management programs and policies, and the Great Basin Restoration Initiative encourage the use of native species for rangeland rehabilitation and restoration where feasible. This project was initiated to foster the development of...

Great Basin Native Plant Selection and Increase Project: 2011 Progress Report

Treesearch

Nancy Shaw; Mike Pellant

2012-01-01

The Interagency native Plant Materials Development Program outlined in the 2002 Report to Congress (USDI and USDA 2002), USDI Bureau of Land Management programs and policies, and the Great Basin Restoration Initiative encourage the use of native species for rangeland rehabilitation and restoration where feasible. This project was initiated to foster the development of...

Comparative Academic Performance at the Baccalaureate Level Between Graduate Transferees at Nassau Community College and Native Students at Selected Public/Private Institutions.

ERIC Educational Resources Information Center

Fernandez, Thomas V., Jr.; And Others

The academic performance of 1973 graduate transferees from Nassau Community College (NCC) was compared at the baccalaureate level with 1975 native student graduates from 12 four-year public and private colleges and universities. These senior institutions were selected on the basis of the large number of NCC transferees they received. The…

Tolerance to wood preservatives by copper-tolerant wood-rot fungi native to south-central Chile.

PubMed

Guillén, Yudith; Navias, David; Machuca, Angela

2009-02-01

Understanding the effect of heavy metals and wood preservatives on the growth of wood-rot fungi native to a certain region may improve reliability in determining the effectiveness of antifungal products, particularly when dealing with new formulations. In this investigation, strains of copper-tolerant wood-rot fungi native to south-central Chile were evaluated against two preservatives: commercial chromated copper arsenate type C (CCA-C) and a new formulation with boron and silicon (BS). Thirteen native strains, mainly white-rot fungi, were selected for their high growth rates in solid medium containing 3 mM of copper. A short-term test was then carried out, consisting of adding cellulose disks impregnated with different concentrations of preservatives to solid culture media inoculated with selected copper tolerant strains. There was a great variability in interspecific and intraspecific responses to the presence of copper and preservatives in culture media. Among the native and commercial strains evaluated, the white-rot fungi Trametes versicolor 38 and mainly Ganoderma australe 100 were notable for their tolerance to all the CCA-C and BS concentrations. The brown-rot fungus Wolfiporia cocos, used as reference strain, showed a high tolerance to CCA-C, but not to BS preservative. T. versicolor 38 and G. australe 100 were selected for subsequent studies on preserved wood degradation.

Contemporary evolution during invasion: evidence for differentiation, natural selection, and local adaptation.

PubMed

Colautti, Robert I; Lau, Jennifer A

2015-05-01

Biological invasions are 'natural' experiments that can improve our understanding of contemporary evolution. We evaluate evidence for population differentiation, natural selection and adaptive evolution of invading plants and animals at two nested spatial scales: (i) among introduced populations (ii) between native and introduced genotypes. Evolution during invasion is frequently inferred, but rarely confirmed as adaptive. In common garden studies, quantitative trait differentiation is only marginally lower (~3.5%) among introduced relative to native populations, despite genetic bottlenecks and shorter timescales (i.e. millennia vs. decades). However, differentiation between genotypes from the native vs. introduced range is less clear and confounded by nonrandom geographic sampling; simulations suggest this causes a high false-positive discovery rate (>50%) in geographically structured populations. Selection differentials (¦s¦) are stronger in introduced than in native species, although selection gradients (¦β¦) are not, consistent with introduced species experiencing weaker genetic constraints. This could facilitate rapid adaptation, but evidence is limited. For example, rapid phenotypic evolution often manifests as geographical clines, but simulations demonstrate that nonadaptive trait clines can evolve frequently during colonization (~two-thirds of simulations). Additionally, QST-FST studies may often misrepresent the strength and form of natural selection acting during invasion. Instead, classic approaches in evolutionary ecology (e.g. selection analysis, reciprocal transplant, artificial selection) are necessary to determine the frequency of adaptive evolution during invasion and its influence on establishment, spread and impact of invasive species. These studies are rare but crucial for managing biological invasions in the context of global change. © 2015 John Wiley & Sons Ltd.

32 CFR 1657.4 - Consideration of claims.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 6 2010-07-01 2010-07-01 false Consideration of claims. 1657.4 Section 1657.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM OVERSEAS... reclassification, by the board having geographic jurisdiction over his permanent address within the United States...

32 CFR 1657.4 - Consideration of claims.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 32 National Defense 6 2011-07-01 2011-07-01 false Consideration of claims. 1657.4 Section 1657.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM OVERSEAS... reclassification, by the board having geographic jurisdiction over his permanent address within the United States...

32 CFR 1657.4 - Consideration of claims.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 32 National Defense 6 2013-07-01 2013-07-01 false Consideration of claims. 1657.4 Section 1657.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM OVERSEAS... reclassification, by the board having geographic jurisdiction over his permanent address within the United States...

32 CFR 1657.4 - Consideration of claims.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 32 National Defense 6 2012-07-01 2012-07-01 false Consideration of claims. 1657.4 Section 1657.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM OVERSEAS... reclassification, by the board having geographic jurisdiction over his permanent address within the United States...

32 CFR 1657.4 - Consideration of claims.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 32 National Defense 6 2014-07-01 2014-07-01 false Consideration of claims. 1657.4 Section 1657.4 National Defense Other Regulations Relating to National Defense SELECTIVE SERVICE SYSTEM OVERSEAS... reclassification, by the board having geographic jurisdiction over his permanent address within the United States...

Functional selectivity of G-protein-coupled receptors: from recombinant systems to native human cells.

PubMed

Seifert, Roland

2013-10-01

In the mid 1990s, it was assumed that a two-state model, postulating an inactive (R) state and an active (R*) state provides the molecular basis for GPCR activation. However, it became clear that this model could not accommodate many experimental observations. Accordingly, the two-state model was superseded by a multi-state model according to which any given ligand stabilizes a unique receptor conformation with distinct capabilities of activating down-stream G-proteins and β-arrestin. Much of this research was conducted with the β2-adrenoceptor in recombinant systems. At the molecular level, there is now no doubt anymore that ligand-specific receptor conformations, also referred to as functional selectivity, exist. This concept holds great potential for drug discovery in terms of developing drugs with higher selectivity for specific cells and/or cell functions and fewer side effects. A major challenge is the analysis for functional selectivity in native cells. Here, I discuss our current knowledge on functional selectivity of three representative GPCRs, the β2-adrenoceptor and the histamine H2- and H4-receptors, in recombinant systems and native human cells. Studies with human neutrophils and eosinophils support the concept of functional selectivity. A major strategy for the analysis of functional selectivity in native cells is to generate complete concentration/response curves with a large set of structurally diverse ligands for multiple parameters. Next, correlations of potencies and efficacies are analyzed, and deviations of the correlations from linearity are indicative for functional selectivity. Additionally, pharmacological inhibitors are used to dissect cell functions from each other. Copyright © 2013 Elsevier Inc. All rights reserved.

Women Are Better at Selecting Gifts than Men

PubMed Central

Pollmann, Monique M. H.; van Beest, Ilja

2013-01-01

There is a widespread belief that women are better at selecting gifts than men; however, this claim has not been assessed on the basis of objective criteria. The current studies do exactly that and show that women do indeed make better gift selections for others, regardless of the gender of the receiver and the type of relationship between the giver and receiver. We investigate the mediating role of different aspects of interpersonal sensitivity and reveal that differences in interpersonal interest (measured with an autism questionnaire), but not differences in interpersonal reactivity, explain gender differences in gift selection quality. The current studies thus present the first objective evidence for the claim that women are better in selecting gifts for others and also give an indication of why this is the case. PMID:24386082

Persistence of Native Trees in an Invaded Hawaiian Lowland Wet Forest: Experimental Evaluation of Light and Water Constraints

Treesearch

Jodie R. Schulten; T. Colleen Cole; Susan Cordell; Keiko M. Publico; Rebecca Ostertag; Jaime E. Enoka; Jené D. Michaud

2014-01-01

Hawaiian lowland wet forests are heavily invaded and their restoration is most likely to be successful if native species selected for restoration have efficient resource-use traits. We evaluated growth, survival, and ecophysiological responses of four native and four invasive species in a greenhouse experiment that simulated reduced light and water conditions commonly...

Community Health Representatives: A Valuable Resource for Providing Coronary Heart Disease Health Education Activities for Native Americans.

ERIC Educational Resources Information Center

Cleaver, Vicki L.

1989-01-01

This article addresses select health issues of Native Americans, emphasizing coronary heart disease (CHD). The link between lifestyle and CHD is discussed. CHD risk data from a study of 67 Community Health Representatives is presented, and the role these paraprofessionals can play in health education among Native Americans is discussed. (IAH)

Going on to Graduate or Professional School: Sources of Financial Aid and Educational Programs for Native Americans.

ERIC Educational Resources Information Center

McKusick, John A., Ed.

The booklet provides brief information on about 250 sources of financial aid and educational programs for Native Americans wanting to enter graduate or professional level study. Most of those listed have been selected because they are earmarked for minority group students as a general group or Native Americans specifically. Section I contains…

Claim validity of print advertisements found in otolaryngology journals.

PubMed

Del Signore, Anthony; Murr, Andrew H; Lustig, Lawrence R; Platt, Michael P; Jalisi, Scharukh; Pratt, Loring W; Spiegel, Jeffrey H

2011-08-01

To evaluate the accuracy and scientific evidence supporting product claims made in print advertisements within otolaryngology journals. Cross-sectional survey with literature review and multiple-reviewer evaluation. Fifty claims made within 23 unique advertisements found in prominent otolaryngology journals were selected. References to support the claims were provided within the advertisements or obtained through direct request to the manufacturer. Five academic otolaryngologists with distinct training and geographic practice locations reviewed the claims and supporting evidence. Each physician had substantial experience as an editorial reviewer, and several had specific training in research methodology and scientific methods. Of the 50 claims, only 14 were determined to be based on strong evidence (28%). With regard to the supporting references, 32 references were published sources (76%), while 3 references were package inserts and/or prescribing information (7%). Interobserver agreement among the reviewers overall was poor; however, when 3 or more of the reviewers were in agreement, only 10% of the claims were deemed correct (n = 5). Reviewers also noted that only 6% of the claims were considered well supported (n = 3). Advertisers make claims that appear in respectable journals, but greater than half of the claims reviewed were not supported by the provided reference materials.

Prevalence and description of selective mutism in immigrant and native families: a controlled study.

PubMed

Elizur, Yoel; Perednik, Ruth

2003-12-01

To assess the incidence of selective mutism (SM) in West Jerusalem's state preschools and evaluate social anxiety/phobia disposition (SAP), social competence (SC), markers of neurodevelopmental delay/disorder (NDD), mothers' psychological adjustment, and marital conflict in immigrant and native children with SM and their matched controls. Mothers of 9 immigrant and 10 native children with SM and their matched controls completed questionnaires evaluating themselves, their marriages, and their children. A response rate of 30% (19/64) was obtained. The general prevalence of SM was 0.76%, while the rate among immigrants was 2.2%. Except for mothers' adjustment, all immigrant/native group effects were significant. There were significant interactions between the SM/control and immigrant/native groups for SAP, NDD, and SC. Immigrant children with SM had higher SAP and SC scores and lower NDD scores than native children with SM. This study distinguished between homogenous (socially anxious) and comorbid children with SM. In this sample, the disorder appeared to be associated with a combination of a specific diathesis (SAP) with intrinsic (NDD) and/or environmental (family immigration) vulnerabilities. Marital discord appeared to be a general risk factor for SM.

Revisiting the Quinoxalinedione Scaffold in the Construction of New Ligands for the Ionotropic Glutamate Receptors.

PubMed

Demmer, Charles S; Rombach, David; Liu, Na; Nielsen, Birgitte; Pickering, Darryl S; Bunch, Lennart

2017-11-15

More than two decades ago, the quinoxalinedione scaffold was shown to act as an α-amino acid bioisoster. Following extensive structure-activity relationship (SAR) studies, the antagonists DNQX, CNQX, and NBQX in the ionotropic glutamate receptor field were identified. In this work, we revisit the quinoxalinedione scaffold and explore the incorporation of an acid functionality in the 6-position. The SAR studies disclose that by this strategy it was possible to tune in iGluR selectivity among the AMPA, NMDA, and KA receptors, and to some extent also obtain full receptor subtype selectivity. Highlights of the study of 44 new analogues are compound 2m being a high affinity ligand for native AMPA receptors (IC 50 = 0.48 μM), analogues 2e,f,h,k,v all displayed selectivity for native NMDA receptors, and compounds 2s,t,u are selective ligand for the GluK1 receptor. Most interestingly, compound 2w was shown to be a GluK3-preferring ligand with full selectivity over native AMPA, KA and NMDA receptors.

Obligate multivalent recognition of cell surface tomoregulin following selection from a multivalent phage antibody library.

PubMed

Heitner, Tara; Satozawa, Noboru; McLean, Kirk; Vogel, David; Cobb, Ronald R; Liu, Bing; Mahmoudi, Mithra; Finster, Silke; Larsen, Brent; Zhu, Ying; Zhou, Hongxing; Müller-Tiemann, Beate; Monteclaro, Felipe; Zhao, Xiao-Yan; Light, David R

2006-12-01

A therapeutic antibody candidate (AT-19) isolated using multivalent phage display binds native tomoregulin (TR) as a mul-timer not as a monomer. This report raises the importance of screening and selecting phage antibodies on native antigen and reemphasizes the possibility that potentially valuable antibodies are discarded when a monomeric phage display system is used for screening. A detailed live cell panning selection and screening method to isolate multivalently active antibodies is described. AT-19 is a fully human antibody recognizing the cell surface protein TR, a proposed prostate cancer target for therapeutic antibody internalization. AT-19 was isolated from a multivalent single-chain variable fragment (scFv) antibody library rescued with hyperphage. The required multivalency for isolation of AT-19 is supported by fluorescence activated cell sorting data demonstrating binding of the multivalent AT-19 phage particles at high phage concentrations and failure of monovalent particles to bind. Pure monomeric scFv AT-19 does not bind native receptor on cells, whereas dimeric scFv or immunoglobulin G binds with nanomolar affinity. The isolation of AT-19 antibody with obligate bivalent binding activity to native TR is attributed to the use of a multivalent display of scFv on phage and the method for selecting and screening by alternate use of 2 recombinant cell lines.

Behavioral variation post-invasion: resemblance in some, but not all, behavioral patterns among invasive and native praying mantids.

PubMed

Jones, Cameron; DiRienzo, Nicolas

2018-05-23

Animal invasions can be devastating for native species. Behavioral variation is known to influence animal invasions, yet comparatively less is known about how behavioral variation influences invasive-native species interactions. Here we examined how the mean and variance surrounding several behavioral traits in two sympatric species of praying mantis differ and how these behavioral types translate to actual prey capture success using the introduced European mantis, Mantis religiosa, and the native bordered mantis, Stagmomantis limbata. We assayed time spent in the open (risk proneness), response towards a novel prey, and voracity within a population of M. religiosa and S. limbata. We found that the native and invasive mantids displayed no differences in their average behavioral tendencies. The native exhibited significant levels of repeatability in voracity while the invasive did not. The lack of repeatability in the invasive appears to be driven by lower levels of among-individual variation in voracity. This may have evolutionary consequences for native S. limbata if it results in strong selection in native levels of mean and among-individual variation. Significant levels of among-individual differences were found in other behaviors (response to a novel prey and risk proneness) across species, suggesting less selection on invasive behavioral variation in these traits. Risk proneness and response towards a novel prey also formed a behavioral syndrome across species, yet neither behavior was correlated with voracity in either species. Our results illustrate the need to examine the ecological effects of behavioral variation of both invasive and native species to determine how that might impact invasive-native interactions. Copyright © 2018 Elsevier B.V. All rights reserved.

Do Wildfires Promote Woody Species Invasion in a Fire-Adapted Ecosystem? Post-fire Resprouting of Native and Non-native Woody Plants in Central Argentina.

PubMed

Herrero, M Lucrecia; Torres, Romina C; Renison, Daniel

2016-02-01

We asked whether prescribed fire could be a useful management tool to reduce invasion by non-native plants in an ecosystem where native plants are supposed to be adapted to fires. Specifically, we compare the post-fire resprouting response of native and non-native woody species in Chaco Serrano forest of central Argentina. The measurements were carried out in five burnt areas where we selected ten native and seven non-native species. Our response variables were (1) post-fire survival, (2) types of resprouts, and (3) the growth of the resprouts. Our main results show that one year after the fire, survivals of native and non-native species were 0.84 and 0.89, respectively, with variances in survival seven times smaller in the native species group. Type of resprout was also less variable in native species, while growth of the resprouts was similar in native and non-native groups. We interpret that in most cases, the burning a forest with mixed native and non-native plants through prescribed fires will not differentially stop the invasion by non-native woody species even in ecosystems which are presumed to be relatively resistant to fires such as our study area.

Non-native Ants Are Smaller than Related Native Ants.

PubMed

McGlynn, Terrence P

1999-12-01

I compare the sizes of non-native and native ants to evaluate how worker size may be related to the ability of a species to invade new habitats. I compare the size of 78 non-native ant species belonging to 26 genera with the size of native congeneric species; native ants are larger than non-native ants in 22 of 26 genera. Ants were sorted by genera into fighting and nonfighting groups, based on observations of interspecific interactions with other ant species. In all of the genera with monomorphic worker castes that fight during competition, the non-native species were smaller than the native species. The genera that engage in combat had a higher frequency of significantly smaller size in non-native ants. I selected Wasmannia auropunctata for further studies, to compare native and non-native populations. Specimens of W. auropunctata from non-native populations were smaller than conspecific counterparts from its native habitat. I consider hypotheses to explain why non-native ants are smaller in size than native ants, including the role of colony size in interspecific fights, changes in life history, the release from intraspecific fighting, and climate. The discovery that fighting non-natives are smaller than their closest native relatives may provide insight into the mechanisms for success of non-native species, as well as the role of worker size and colony size during interspecific competition.

Meal Counting and Claiming Manual.

ERIC Educational Resources Information Center

Food and Nutrition Service (USDA), Washington, DC.

This manual contains information about the selection and implementation of a meal counting and claiming system for the National School Lunch Program (NSLP) and the School Breakfast Program (BSP). Federal reimbursement is provided for each meal that meets program requirements and is served to an eligible student. Part 1 explains the six elements of…

European consumers and health claims: attitudes, understanding and purchasing behaviour.

PubMed

Wills, Josephine M; Storcksdieck genannt Bonsmann, Stefan; Kolka, Magdalena; Grunert, Klaus G

2012-05-01

Health claims on food products are often used as a means to highlight scientifically proven health benefits associated with consuming those foods. But do consumers understand and trust health claims? This paper provides an overview of recent research on consumers and health claims including attitudes, understanding and purchasing behaviour. A majority of studies investigated selective product-claim combinations, with ambiguous findings apart from consumers' self-reported generic interest in health claims. There are clear indications that consumer responses differ substantially according to the nature of carrier product, the type of health claim, functional ingredient used or a combination of these components. Health claims tend to be perceived more positively when linked to a product with an overall positive health image, whereas some studies demonstrate higher perceived credibility of products with general health claims (e.g. omega-3 and brain development) compared to disease risk reduction claims (e.g. bioactive peptides to reduce risk of heart disease), others report the opposite. Inconsistent evidence also exists on the correlation between having a positive attitude towards products with health claims and purchase intentions. Familiarity with the functional ingredient and/or its claimed health effect seems to result in a more favourable evaluation. Better nutritional knowledge, however, does not automatically lead to a positive attitude towards products carrying health messages. Legislation in the European Union requires that the claim is understood by the average consumer. As most studies on consumers' understanding of health claims are based on subjective understanding, this remains an area for more investigation.

Nutrition and health claims on healthy and less-healthy packaged food products in New Zealand.

PubMed

Al-Ani, Haya H; Devi, Anandita; Eyles, Helen; Swinburn, Boyd; Vandevijvere, Stefanie

2016-09-01

Nutrition and health claims are displayed to influence consumers' food choices. This study assessed the extent and nature of nutrition and health claims on the front-of-pack of 'healthy' and 'less-healthy' packaged foods in New Zealand. Foods from eight categories, for which consumption may affect the risk of obesity and diet-related chronic diseases, were selected from the 2014 Nutritrack database. The internationally standardised International Network for Food and Obesity/Non-Communicable Diseases Research, Monitoring and Action Support (INFORMAS) taxonomy was used to classify claims on packages. The Nutrient Profiling Scoring Criterion (NPSC) was used to classify products as 'healthy' or 'less healthy'. In total, 7526 products were included, with 47 % (n 3557) classified as 'healthy'. More than one-third of products displayed at least one nutrition claim and 15 % featured at least one health claim on the front-of-pack. Claims were found on one-third of 'less-healthy' products; 26 % of those products displayed nutrition claims and 7 % featured health claims. About 45 % of 'healthy' products displayed nutrition claims and 23 % featured health claims. Out of 7058 individual claims, the majority (69 %) were found on 'healthy' products. Cereals displayed the greatest proportion of nutrition and health claims (1503 claims on 564 products), of which one-third were displayed on 'less-healthy' cereals. Such claims could be misleading consumers' perceptions of nutritional quality of foods. It needs to be explored how current regulations on nutrition and health claims in New Zealand could be further strengthened (e.g. using the NPSC for nutrition claims, including general health claims as per the INFORMAS taxonomy) to ensure consumers are protected and not misled.

USING PHOTOVOICE WITH YOUTH TO DEVELOP A DRUG PREVENTION PROGRAM IN A RURAL HAWAIIAN COMMUNITY

PubMed Central

Helm, Susana; Lee, Wayde; Hanakahi, Vanda; Gleason, Krissy; McCarthy, Kayne

2015-01-01

Introduction Substance use represents a significant and persistent health disparity among Native Hawaiian youth and communities. A community-university participatory action research project was conducted to develop a Native Hawaiian model of drug prevention. Methods Ten youth participated in eight Photovoice focus groups. Focus group transcripts and the youths’ SHOWED (see, happening, our, why, empower, do) worksheets were analyzed. Results Emergent analyses are described regarding focus group theme identification and the meaning of each theme. Youth-selected exemplary photographs and researcher-selected exemplary quotations are provided. Implications Native Hawaiian drug prevention will be place-based in culturally significant community locations, experiential, and guided by multigenerational teaching and learning. PMID:25768388

The problems inherent in teaching technical writing and report writing to native Americans

NASA Technical Reports Server (NTRS)

Zukowski/faust, J.

1981-01-01

Teaching technical writing to Native Americans contending with a second language and culture is addressed. Learning difficulties arising from differences between native and acquired language and cultural systems are examined. Compartmentalized teaching, which presents the ideals of technical writing in minimal units, and skills development are considered. Rhetorical problems treated include logic of arrangement, selection of support and scope of detail, and time and space. Specific problems selected include the concept of promptness, the contextualization of purpose, interpersonal relationships, wordiness, mixture of registers, and the problem of abstracting. Four inductive procedures for students having writing and perception problems are included. Four sample exercises and a bibliography of 13 references are also included.

Are Front of Pack Claims Indicators of Nutrition Quality? Evidence from 2 Product Categories.

PubMed

Schaefer, Debra; Hooker, Neal H; Stanton, John L

2016-01-01

American grocery shoppers face an array of front of pack (FOP) nutrition and health claims when making food selections. Such systems have been categorized as summary or nutrient specific. Either type should help consumers make judgments about the nutrition quality of a product. This research tests if the type or quantity of FOP claims are indeed good indicators of objective nutrition quality. Claim and nutrition information from more than 2200 breakfast cereals and prepared meals launched between 2006 and 2010 were analyzed using binary and multinomial logistic regression models. Results suggest that no type or number of front of pack claims could distinguish "healthy" foods. However, some types and frequencies of FOP claims were significant predictors of higher or lower levels of certain key nutrients. Given the complex and crowded label environment in which these FOP claims reside, one may be concerned that such cues are not closely related to objective measures of nutrition quality. © 2015 Institute of Food Technologists®

Reclamation of skid roads with fiber mats and native vegetation: effects on erosion

Treesearch

shawn T. Grushecky; David w. McGill; William Grafton; John Edwards; Lisa Tager

2007-01-01

A research study was established to test the effectiveness of fiber mats and native seed mixtures in reducing soil erosion from newly-constructed skid roads in the Elk River Watershed in central West Virginia. Twelve road sections of equal grade were paired with a randomly-selected section receiving a fiber mat and native grass seed while the other road section was not...

Earth melter with rubble walls and method of use

DOEpatents

Chapman, Chris C.

1998-01-01

The present invention is an improvement to the earth melter described and claimed in U.S. Pat. No. 5,443,618. The improvement is the use of rubble for retaining walls. More specifically, the retaining walls rest on ground level and extend above ground level piling rubble around a melt zone. A portion of the melter may be below grade wherein sidewalls are formed by the relatively undisturbed native soil or rock, and the rubble may be used as a backfill liner for the below grade sidewalls.

Native American Children, Youth, and Families. Part 1. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, Ninety-Ninth Congress, Second Session (Seattle, WA, January 7, 1986).

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

The House Select Committee met to receive testimony from representatives of Northwest tribes about conditions affecting Native American children and their families. Eloise King of Colville Confederated Tribes (Washington) summarizes a wide range of human needs and recommends that Congress make funding available directly to tribes. John Navarro and…

Native American Children, Youth, and Families. Part 3. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, Ninety-Ninth Congress, Second Session (Albuquerque, NM, January 10, 1986).

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

As part of a weeklong investigation into conditions among Native American families and children, the House of Representatives Select Committee on Children, Youth, and Families met to hear testimony from tribal leaders, parents, young adults, and service providers from reservations and pueblos in New Mexico and Colorado. Topics include unemployment…

Race and nicotine replacement treatment outcomes among low-income smokers.

PubMed

Fu, Steven S; Burgess, Diana J; Hatsukami, Dorothy K; Noorbaloochi, Siamak; Clothier, Barbara A; Nugent, Sean; van Ryn, Michelle

2008-12-01

Prior research suggests that racial/ethnic minority smokers experience more difficulty with cessation than white smokers and access formal treatment less often. Minority smokers may respond differently to treatment interventions than white smokers. This prospective, observational cohort study compared long-term cessation outcomes among four racial/ethnic groups after an aided quit attempt using nicotine replacement therapy (NRT). A random cohort of smokers (N=1782) who recently filled a prescription for NRT was selected, stratified by race, using Minnesota Health Care Programs (e.g., Medicaid) pharmacy claims databases between July 2005 and September 2006. The primary outcome was 7-day point prevalence abstinence, which was assessed about 8 months after the NRT index prescription fill date using a mixed-mode survey protocol. The overall survey response was 58.2%. Overall, abstinence outcomes did not significantly vary by race. Unadjusted comparisons show that among survey respondents, at 8 months, 7-day point prevalence abstinence was 13.8% among whites, 13.6% among blacks, 14.1% among American Indians/Alaska Natives, and 20.7% among Asians (p=0.42). Similarly, the 30-day duration abstinence was 10.0% among whites, 11.5% among blacks, 8.9% among American Indians/Alaska Natives, and 18.3% among Asians (p=0.14). In multivariate analysis using propensity adjustment for potential confounding and response bias, there was no evidence that the effectiveness of NRT was lower for racial/ethnic minority smokers compared to white smokers. These findings indicate that racial/ethnic minorities are as likely to quit smoking at a level similar to whites when using cessation treatment that includes NRT. Given documented disparities in the use of evidence-based cessation treatments such as NRT, interventions are sorely needed to improve access and utilization of these treatments in racial/ethnic minority groups.

Spoilage of foods monitored by native fluorescence spectroscopy with selective excitation wavelength

NASA Astrophysics Data System (ADS)

Pu, Yang; Wang, Wubao; Alfano, Robert R.

2015-03-01

The modern food processing and storage environments require the real-time monitoring and rapid microbiological testing. Optical spectroscopy with selective excitation wavelengths can be the basis of a novel, rapid, reagent less, noncontact and non-destructive technique for monitoring the food spoilage. The native fluorescence spectra of muscle foods stored at 2-4°C (in refrigerator) and 20-24°C (in room temperature) were measured as a function of time with a selective excitation wavelength of 340nm. The contributions of the principal molecular components to the native fluorescence spectra of meat were measured spectra of each fluorophore: collagen, reduced nicotinamide adenine dinucleotide (NADH), and flavin. The responsible components were extracted using a method namely Multivariate Curve Resolution with Alternating Least-Squares (MCR-ALS). The native fluorescence combined with MCR-ALS can be used directly on the surface of meat to produce biochemically interpretable "fingerprints", which reflects the microbial spoilage of foods involved with the metabolic processes. The results show that with time elapse, the emission from NADH in meat stored at 24°C increases much faster than that at 4°C. This is because multiplying of microorganisms and catabolism are accompanied by the generation of NADH. This study presents changes of relative content of NADH may be used as criterion for detection of spoilage degree of meat using native fluorescence spectroscopy.

Analysis of native water, bed material, and elutriate samples of major Louisiana waterways, 1975

USGS Publications Warehouse

Demas, Charles R.

1976-01-01

The U.S. Geological Survey, in cooperation with the U.S. Army Corps of Engineers, conducted a series of elutriate studies in selected reaches of major navigable waterways of Louisiana. As defined by the U.S. Environmental Protection Agency, an elutriate is the supernatant resulting from the vigorous 30-minute shaking of one part bottom sediment from the dredging site with four parts water (vol/vol) collected from the dredging site followed by one hour settling time and appropriate centrifugation and a 0.45-micron filtration. The elutriate studies were initiated to evaluate possible environmental effects of proposed dredging activities in selected reaches of Louisiana waterways. The waterways investigated were the Mississippi River-Gulf Outlet, Breton Sound, Mississippi River downstream from Baton Rouge, Bayou Long, Intracoastal Waterway (east and west of the Harvey Canal), Three Rivers area, Ouachita River, Barataria Bay, Houma Navigation Canal, Atchafalaya Bay (Ship Channel), Berwick Bay, Intracoastal Waterway (Port Allen to Morgan City), Petite Anse area, and Calcasieu River and Ship Channel. The Geological Survey collected 227 samples of native water and bed (bottom) material from 130 different sites. These samples (as well as elutriates prepared from mixtures of native water and bed material) were analyzed for selected metal, pesticide, nutrient, and organic constituents. An additional 116 bed samples collected at 58 sites were analyzed for selected pesticides; and 4 additional native-water samples from 2 sites were analyzed for selected metal pesticide, nutrient, and organic constituents. (Woodard-USGS)

Nutrient composition of selected traditional native American plant foods

USDA-ARS?s Scientific Manuscript database

Ten wild plants (cattail narrow leaf shoots, chokecherries, beaked hazelnuts, lambsquarters, plains pricklypear, prairie turnips, stinging nettles, wild plums, raspberries, rose hips) from three Native American reservations in North Dakota were analyzed to expand composition information of tradition...

Novel optimum contribution selection methods accounting for conflicting objectives in breeding programs for livestock breeds with historical migration.

PubMed

Wang, Yu; Bennewitz, Jörn; Wellmann, Robin

2017-05-12

Optimum contribution selection (OCS) is effective for increasing genetic gain, controlling the rate of inbreeding and enables maintenance of genetic diversity. However, this diversity may be caused by high migrant contributions (MC) in the population due to introgression of genetic material from other breeds, which can threaten the conservation of small local populations. Therefore, breeding objectives should not only focus on increasing genetic gains but also on maintaining genetic originality and diversity of native alleles. This study aimed at investigating whether OCS was improved by including MC and modified kinships that account for breed origin of alleles. Three objective functions were considered for minimizing kinship, minimizing MC and maximizing genetic gain in the offspring generation, and we investigated their effects on German Angler and Vorderwald cattle. In most scenarios, the results were similar for Angler and Vorderwald cattle. A significant positive correlation between MC and estimated breeding values of the selection candidates was observed for both breeds, thus traditional OCS would increase MC. Optimization was performed under the condition that the rate of inbreeding did not exceed 1% and at least 30% of the maximum progress was achieved for all other criteria. Although traditional OCS provided the highest breeding values under restriction of classical kinship, the magnitude of MC in the progeny generation was not controlled. When MC were constrained or minimized, the kinship at native alleles increased compared to the reference scenario. Thus, in addition to constraining MC, constraining kinship at native alleles is required to ensure that native genetic diversity is maintained. When kinship at native alleles was constrained, the classical kinship was automatically lowered in most cases and more sires were selected. However, the average breeding value in the next generation was also lower than that obtained with traditional OCS. For local breeds with historical introgressions, current breeding programs should focus on increasing genetic gain and controlling inbreeding, as well as maintaining the genetic originality of the breeds and the diversity of native alleles via the inclusion of MC and kinship at native alleles in the OCS process.

Knowledge and practice of prevention of mother-to-child transmission of HIV among traditional birth attendants in Lagos State, Nigeria.

PubMed

Balogun, Mobolanle; Odeyemi, Kofo

2010-04-29

Traditional birth attendants (TBAs) assist most deliveries in Nigeria. Knowing and understanding all issues surrounding HIV/AIDS and Prevention of Mother-To-Child Transmission of HIV (PMTCT) can help them to protect themselves and others. This study aimed to assess the knowledge and practice of PMTCT amongst TBAs in Lagos, Nigeria. This was a cross-sectional survey. Multistage sampling method was used to select 108 registered TBAs in 2 local governments areas who were interviewed using a pre-tested questionnaire. All the respondents were aware of HIV but their awareness of PMTCT specifically was not as high. Only 8.3% of the respondents had good level of knowledge about HIV and PMTCT and up to 13% of them claimed to be able to cure HIV using native remedies. The practices of HIV counseling of patients and referral of patients for HIV testing were low and higher levels of knowledge positively influenced these practices significantly (p < 0.05). They were also deficient in certain measures to prevent infection of patients and themselves. Most of the TBAs did not have adequate knowledge and practice of PMTCT illustrating the need for periodic PMTCT training for TBAs.

Protein quality control in the early secretory pathway

PubMed Central

Anelli, Tiziana; Sitia, Roberto

2008-01-01

Eukaryotic cells are able to discriminate between native and non-native polypeptides, selectively transporting the former to their final destinations. Secretory proteins are scrutinized at the endoplasmic reticulum (ER)–Golgi interface. Recent findings reveal novel features of the underlying molecular mechanisms, with several chaperone networks cooperating in assisting the maturation of complex proteins and being selectively induced to match changing synthetic demands. ‘Public' and ‘private' chaperones, some of which enriched in specializes subregions, operate for most or selected substrates, respectively. Moreover, sequential checkpoints are distributed along the early secretory pathway, allowing efficiency and fidelity in protein secretion. PMID:18216874

Herbivore Preference for Native vs. Exotic Plants: Generalist Herbivores from Multiple Continents Prefer Exotic Plants That Are Evolutionarily Naïve

PubMed Central

Morrison, Wendy E.; Hay, Mark E.

2011-01-01

Enemy release and biotic resistance are competing, but not mutually exclusive, hypotheses addressing the success or failure of non-native plants entering a new region. Enemy release predicts that exotic plants become invasive by escaping their co-adapted herbivores and by being unrecognized or unpalatable to native herbivores that have not been selected to consume them. In contrast, biotic resistance predicts that native generalist herbivores will suppress exotic plants that will not have been selected to deter these herbivores. We tested these hypotheses using five generalist herbivores from North or South America and nine confamilial pairs of native and exotic aquatic plants. Four of five herbivores showed 2.4–17.3 fold preferences for exotic over native plants. Three species of South American apple snails (Pomacea sp.) preferred North American over South American macrophytes, while a North American crayfish Procambarus spiculifer preferred South American, Asian, and Australian macrophytes over North American relatives. Apple snails have their center of diversity in South America, but a single species (Pomacea paludosa) occurs in North America. This species, with a South American lineage but a North American distribution, did not differentiate between South American and North American plants. Its preferences correlated with preferences of its South American relatives rather than with preferences of the North American crayfish, consistent with evolutionary inertia due to its South American lineage. Tests of plant traits indicated that the crayfish responded primarily to plant structure, the apple snails primarily to plant chemistry, and that plant protein concentration played no detectable role. Generalist herbivores preferred non-native plants, suggesting that intact guilds of native, generalist herbivores may provide biotic resistance to plant invasions. Past invasions may have been facilitated by removal of native herbivores, introduction of non-native herbivores (which commonly prefer native plants), or both. PMID:21394202

20 CFR 404.2121 - Validation reviews.

Code of Federal Regulations, 2011 CFR

2011-04-01

...) General. We will conduct a validation review of a sample of the claims for payment filed by each State VR... by any State VR agency or alternate participant, if we determine that such review is necessary to ensure compliance with the requirements of this subpart. For each claim selected for review, the State VR...

20 CFR 404.2121 - Validation reviews.

Code of Federal Regulations, 2010 CFR

2010-04-01

...) General. We will conduct a validation review of a sample of the claims for payment filed by each State VR... by any State VR agency or alternate participant, if we determine that such review is necessary to ensure compliance with the requirements of this subpart. For each claim selected for review, the State VR...

20 CFR 404.2121 - Validation reviews.

Code of Federal Regulations, 2014 CFR

2014-04-01

...) General. We will conduct a validation review of a sample of the claims for payment filed by each State VR... by any State VR agency or alternate participant, if we determine that such review is necessary to ensure compliance with the requirements of this subpart. For each claim selected for review, the State VR...

20 CFR 404.2121 - Validation reviews.

Code of Federal Regulations, 2012 CFR

2012-04-01

...) General. We will conduct a validation review of a sample of the claims for payment filed by each State VR... by any State VR agency or alternate participant, if we determine that such review is necessary to ensure compliance with the requirements of this subpart. For each claim selected for review, the State VR...

20 CFR 404.2121 - Validation reviews.

Code of Federal Regulations, 2013 CFR

2013-04-01

...) General. We will conduct a validation review of a sample of the claims for payment filed by each State VR... by any State VR agency or alternate participant, if we determine that such review is necessary to ensure compliance with the requirements of this subpart. For each claim selected for review, the State VR...

Meta-Analysis of Inquiry-Based Instruction Research

NASA Astrophysics Data System (ADS)

Hasanah, N.; Prasetyo, A. P. B.; Rudyatmi, E.

2017-04-01

Inquiry-based instruction in biology has been the focus of educational research conducted by Unnes biology department students in collaboration with their university supervisors. This study aimed to describe the methodological aspects, inquiry teaching methods critically, and to analyse the results claims, of the selected four student research reports, grounded in inquiry, based on the database of Unnes biology department 2014. Four experimental quantitative research of 16 were selected as research objects by purposive sampling technique. Data collected through documentation study was qualitatively analysed regarding methods used, quality of inquiry syntax, and finding claims. Findings showed that the student research was still the lack of relevant aspects of research methodology, namely in appropriate sampling procedures, limited validity tests of all research instruments, and the limited parametric statistic (t-test) not supported previously by data normality tests. Their consistent inquiry syntax supported the four mini-thesis claims that inquiry-based teaching influenced their dependent variables significantly. In other words, the findings indicated that positive claims of the research results were not fully supported by good research methods, and well-defined inquiry procedures implementation.

Validation of an administrative claims-based diagnostic code for pneumonia in a US-based commercially insured COPD population

PubMed Central

Kern, David M; Davis, Jill; Williams, Setareh A; Tunceli, Ozgur; Wu, Bingcao; Hollis, Sally; Strange, Charlie; Trudo, Frank

2015-01-01

Objective To estimate the accuracy of claims-based pneumonia diagnoses in COPD patients using clinical information in medical records as the reference standard. Methods Selecting from a repository containing members’ data from 14 regional United States health plans, this validation study identified pneumonia diagnoses within a group of patients initiating treatment for COPD between March 1, 2009 and March 31, 2012. Patients with ≥1 claim for pneumonia (International Classification of Diseases Version 9-CM code 480.xx–486.xx) were identified during the 12 months following treatment initiation. A subset of 800 patients was randomly selected to abstract medical record data (paper based and electronic) for a target sample of 400 patients, to estimate validity within 5% margin of error. Positive predictive value (PPV) was calculated for the claims diagnosis of pneumonia relative to the reference standard, defined as a documented diagnosis in the medical record. Results A total of 388 records were reviewed; 311 included a documented pneumonia diagnosis, indicating 80.2% (95% confidence interval [CI]: 75.8% to 84.0%) of claims-identified pneumonia diagnoses were validated by the medical charts. Claims-based diagnoses in inpatient or emergency departments (n=185) had greater PPV versus outpatient settings (n=203), 87.6% (95% CI: 81.9%–92.0%) versus 73.4% (95% CI: 66.8%–79.3%), respectively. Claims-diagnoses verified with paper-based charts had similar PPV as the overall study sample, 80.2% (95% CI: 71.1%–87.5%), and higher PPV than those linked to electronic medical records, 73.3% (95% CI: 65.5%–80.2%). Combined paper-based and electronic records had a higher PPV, 87.6% (95% CI: 80.9%–92.6%). Conclusion Administrative claims data indicating a diagnosis of pneumonia in COPD patients are supported by medical records. The accuracy of a medical record diagnosis of pneumonia remains unknown. With increased use of claims data in medical research, COPD researchers can study pneumonia with confidence that claims data are a valid tool when studying the safety of COPD therapies that could potentially lead to increased pneumonia susceptibility or severity. PMID:26229461

Validation of an administrative claims-based diagnostic code for pneumonia in a US-based commercially insured COPD population.

PubMed

Kern, David M; Davis, Jill; Williams, Setareh A; Tunceli, Ozgur; Wu, Bingcao; Hollis, Sally; Strange, Charlie; Trudo, Frank

2015-01-01

To estimate the accuracy of claims-based pneumonia diagnoses in COPD patients using clinical information in medical records as the reference standard. Selecting from a repository containing members' data from 14 regional United States health plans, this validation study identified pneumonia diagnoses within a group of patients initiating treatment for COPD between March 1, 2009 and March 31, 2012. Patients with ≥1 claim for pneumonia (International Classification of Diseases Version 9-CM code 480.xx-486.xx) were identified during the 12 months following treatment initiation. A subset of 800 patients was randomly selected to abstract medical record data (paper based and electronic) for a target sample of 400 patients, to estimate validity within 5% margin of error. Positive predictive value (PPV) was calculated for the claims diagnosis of pneumonia relative to the reference standard, defined as a documented diagnosis in the medical record. A total of 388 records were reviewed; 311 included a documented pneumonia diagnosis, indicating 80.2% (95% confidence interval [CI]: 75.8% to 84.0%) of claims-identified pneumonia diagnoses were validated by the medical charts. Claims-based diagnoses in inpatient or emergency departments (n=185) had greater PPV versus outpatient settings (n=203), 87.6% (95% CI: 81.9%-92.0%) versus 73.4% (95% CI: 66.8%-79.3%), respectively. Claims-diagnoses verified with paper-based charts had similar PPV as the overall study sample, 80.2% (95% CI: 71.1%-87.5%), and higher PPV than those linked to electronic medical records, 73.3% (95% CI: 65.5%-80.2%). Combined paper-based and electronic records had a higher PPV, 87.6% (95% CI: 80.9%-92.6%). Administrative claims data indicating a diagnosis of pneumonia in COPD patients are supported by medical records. The accuracy of a medical record diagnosis of pneumonia remains unknown. With increased use of claims data in medical research, COPD researchers can study pneumonia with confidence that claims data are a valid tool when studying the safety of COPD therapies that could potentially lead to increased pneumonia susceptibility or severity.

A functional ABCA1 gene variant is associated with low HDL-cholesterol levels and shows evidence of positive selection in Native Americans

PubMed Central

Acuña-Alonzo, Víctor; Flores-Dorantes, Teresa; Kruit, Janine K.; Villarreal-Molina, Teresa; Arellano-Campos, Olimpia; Hünemeier, Tábita; Moreno-Estrada, Andrés; Ortiz-López, Ma Guadalupe; Villamil-Ramírez, Hugo; León-Mimila, Paola; Villalobos-Comparan, Marisela; Jacobo-Albavera, Leonor; Ramírez-Jiménez, Salvador; Sikora, Martin; Zhang, Lin-Hua; Pape, Terry D.; de Ángeles Granados-Silvestre, Ma; Montufar-Robles, Isela; Tito-Alvarez, Ana M.; Zurita-Salinas, Camilo; Bustos-Arriaga, José; Cedillo-Barrón, Leticia; Gómez-Trejo, Celta; Barquera-Lozano, Rodrigo; Vieira-Filho, Joao P.; Granados, Julio; Romero-Hidalgo, Sandra; Huertas-Vázquez, Adriana; González-Martín, Antonio; Gorostiza, Amaya; Bonatto, Sandro L.; Rodríguez-Cruz, Maricela; Wang, Li; Tusié-Luna, Teresa; Aguilar-Salinas, Carlos A.; Lisker, Ruben; Moises, Regina S.; Menjivar, Marta; Salzano, Francisco M.; Knowler, William C.; Bortolini, M. Cátira; Hayden, Michael R.; Baier, Leslie J.; Canizales-Quinteros, Samuel

2010-01-01

It has been suggested that the higher susceptibility of Hispanics to metabolic disease is related to their Native American heritage. A frequent cholesterol transporter ABCA1 (ATP-binding cassette transporter A1) gene variant (R230C, rs9282541) apparently exclusive to Native American individuals was associated with low high-density lipoprotein cholesterol (HDL-C) levels, obesity and type 2 diabetes in Mexican Mestizos. We performed a more extensive analysis of this variant in 4405 Native Americans and 863 individuals from other ethnic groups to investigate genetic evidence of positive selection, to assess its functional effect in vitro and to explore associations with HDL-C levels and other metabolic traits. The C230 allele was found in 29 of 36 Native American groups, but not in European, Asian or African individuals. C230 was observed on a single haplotype, and C230-bearing chromosomes showed longer relative haplotype extension compared with other haplotypes in the Americas. Additionally, single-nucleotide polymorphism data from the Human Genome Diversity Panel Native American populations were enriched in significant integrated haplotype score values in the region upstream of the ABCA1 gene. Cells expressing the C230 allele showed a 27% cholesterol efflux reduction (P< 0.001), confirming this variant has a functional effect in vitro. Moreover, the C230 allele was associated with lower HDL-C levels (P = 1.77 × 10−11) and with higher body mass index (P = 0.0001) in the combined analysis of Native American populations. This is the first report of a common functional variant exclusive to Native American and descent populations, which is a major determinant of HDL-C levels and may have contributed to the adaptive evolution of Native American populations. PMID:20418488

Native American Children, Youth, and Families. Part 2. Hearing before the Select Committee on Children, Youth, and Families. House of Representatives, Ninety-Ninth Congress, Second Session (Sacaton, AZ, January 9, 1986).

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

The House Select Committee met to hear testimony of six witnesses from tribes in the Phoenix, Arizona area concerning the status of Native American children and their families. General topics were the nature of existing human service programs, adequacy of federal funding, and magnitude of health and welfare needs. Tom White of the Gila River…

Analyses of native water, bottom material, elutriate samples, and dredged material from selected southern Louisiana waterways and selected areas in the Gulf of Mexico, 1979-81

USGS Publications Warehouse

Lurry, Dee L.

1983-01-01

The U.S. Geological Survey was requested by the U.S. Army Corps of Engineers, New Orleans District, to provide water-quality data to evaluate environmental effects of dredging activities in selected reaches of the Calcasieu River in southwestern Louisiana. Samples were collected from the upper and lower Calcasieu River between January 1980 and March 1981. Thirty-three samples (22 native-water and 11 effluent) were collected from eleven dredging sites. In addition, a series of elutriate studies were conducted between July 1979 and July 1981 to determine water quality as a basis for assessing possible environmental effects of proposed dredging activities in the following areas: Grand Bayou and Martins Canal near Happy Jack, unnamed bayou near Port Sulphur, Grand Bayou and Pipeline Canal near Port Sulphur and Bayou des Plantins near Empire; Mississippi River Gulf Outlet and Inner Harbor Navigation Canal; Southwest Pass; Barataria Bay; Atchafalaya Bay at Eugene Island; Calcasieu Ship Channel. Samples of native water and samples of bottom material were collected from 22 different sites and elutriate (mixtures of native water and bottom material) samples were prepared and analyzed. Four proposed ocean-disposal sites were sampled for bottom material only. Samples were analyzed for selected chemical and biological constituents and physical properties. (USGS)

Effects of electronic prescribing on formulary compliance and generic drug utilization in the ambulatory care setting: a retrospective analysis of administrative claims data.

PubMed

Ross, S Michael; Papshev, Diana; Murphy, Erin L; Sternberg, David J; Taylor, Jeffrey; Barg, Ronald

2005-06-01

Electronic prescribing (e-prescribing) provides formulary information at the point of care. The objective of this study was to assess the effects of e-prescribing on formulary compliance and generic utilization. This was a retrospective analysis of pharmacy claims data from a large national managed care organization. A sample of 95 providers using predominantly e-prescribing was randomly selected (e-prescriber group). A matched sample of 95 traditional prescribers was selected (traditional prescriber group), matched to the e-prescriber group by zip code and medical specialty. A total of 110,975 paid pharmacy claims, for the 12 months from August 1, 2001, through July 31, 2002, were analyzed to assess the effect of e-prescribing on formulary compliance and generic utilization. All paid pharmacy claims were examined for each group; for the e-prescriber group, this included all claims, not just those prescribed using an e-prescribing device. A written qualitative survey was distributed to physicians and office managers to assess e-prescribing usage, sources of formulary information, and effects of e-prescribing on office resources. Both predominantly e-prescribers and traditional prescribers demonstrated high levels of formulary compliance, 83.2% versus 82.8%, respectively (P=0.32). Formulary compliance for these groups did not differ from the overall prescriber population (82.0%). There was not a difference in generic drug utilization rates between e-prescribers and traditional prescribers (absolute rates 37.3% versus 36.9%, P=0.18). Qualitative survey responses supported previously reported research indicating reductions in calls both to and from pharmacies for prescription orders. An examination of paid pharmacy claims from a large, national managed care organization demonstrated no differences between predominantly e-prescribers and traditional prescribers in measures of formulary compliance or generic drug utilization. Future studies should examine keystroke data at the point of care to observe more detail about drug selection methods.

Vitamin-Fortified Snack Food May Lead Consumers to Make Poor Dietary Decisions.

PubMed

Verrill, Linda; Wood, Dallas; Cates, Sheryl; Lando, Amy; Zhang, Yuanting

2017-03-01

The US Food and Drug Administration's (FDA's) fortification policy discourages the fortification of certain foods, including sugars and snack foods such as cookies, candies, cakes, chips, and carbonated beverages, yet manufacturers sometimes add vitamins and minerals to snack foods. To assess whether vitamin-fortified snack foods affect consumers' information-seeking, purchase decisions, and product-related health perceptions. For this experimental study, participants were randomly assigned to study conditions to compare products that varied in product type, nutrition profile, and fortification and nutrient claim status. Data were collected via an online consumer panel. US adults aged 18 years and older were randomly selected from Research Now's e-panel online household panel. Data were collected during fall 2014 (N=5,076). Participants were randomly assigned to one of 24 conditions: two products (vegetable chip/potato chip), two nutrition profiles (healthier/less healthy), two fortification scenarios (not fortified/fortified), and three nutrient claim conditions (two no claim/one with claim). The design was not balanced; claims were not shown on products that were not vitamin fortified. Outcome measures were information-seeking (viewed the Nutrition Facts label), purchase decisions, perception of product healthfulness, and correct selection of product with the healthier nutrient profile. Logistic regression was used to test all models. Analyses was adjusted for general label use, consumes product, health status, age, sex, level of education, presence of children in the household, and race/ethnicity. When the snack food carried a nutrient claim for vitamin fortification, participants were 1) less likely to look for nutrition information on the Nutrition Facts label, 2) more likely to select the product for purchase, 3) more likely to perceive the product as healthier, and 4) less likely to correctly choose the healthier product. Snack foods that have been vitamin-fortified may cause consumers to make poor dietary decisions. Copyright © 2017 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

Enabling Linked Science in Global Climate Uncertainty Quantification (UQ) Research

NASA Astrophysics Data System (ADS)

Elsethagen, T.; Stephan, E.; Lin, G.; Williams, D.; Banks, E.

2012-12-01

This paper shares a real-world global climate UQ science use case and illustrates how a linked science application called Provenance Environment (ProvEn), currently being developed, enables and facilitates scientific teams to publish, share, link, and discover new links over their UQ research results. UQ results include terascale datasets that are published to an Earth Systems Grid Federation (ESGF) repository. ProvEn demonstrates how a scientific team conducting UQ studies can discover dataset links using its domain knowledgebase, allowing them to better understand the UQ study research objectives, the experimental protocol used, the resulting dataset lineage, related analytical findings, ancillary literature citations, along with the social network of scientists associated with the study. This research claims that scientists using this linked science approach will not only allow them to greatly benefit from understanding a particular dataset within a knowledge context, a benefit can also be seen by the cross reference of knowledge among the numerous UQ studies being stored in ESGF. ProvEn collects native forms of data provenance resources as the UQ study is carried out. The native data provenance resources can be collected from a variety of sources such as scripts, a workflow engine log, simulation log files, scientific team members etc. Schema alignment is used to translate the native forms of provenance into a set of W3C PROV-O semantic statements used as a common interchange format which will also contain URI references back to resources in the UQ study dataset for querying and cross referencing. ProvEn leverages Fedora Commons' digital object model in a Resource Oriented Architecture (ROA) (i.e. a RESTful framework) to logically organize and partition native and translated provenance resources by UQ study. The ROA also provides scientists the means to both search native and translated forms of provenance.

Rapid fixation of non-native alleles revealed by genome-wide SNP analysis of hybrid tiger salamanders.

PubMed

Fitzpatrick, Benjamin M; Johnson, Jarrett R; Kump, D Kevin; Shaffer, H Bradley; Smith, Jeramiah J; Voss, S Randal

2009-07-24

Hybrid zones represent valuable opportunities to observe evolution in systems that are unusually dynamic and where the potential for the origin of novelty and rapid adaptation co-occur with the potential for dysfunction. Recently initiated hybrid zones are particularly exciting evolutionary experiments because ongoing natural selection on novel genetic combinations can be studied in ecological time. Moreover, when hybrid zones involve native and introduced species, complex genetic patterns present important challenges for conservation policy. To assess variation of admixture dynamics, we scored a large panel of markers in five wild hybrid populations formed when Barred Tiger Salamanders were introduced into the range of California Tiger Salamanders. At three of 64 markers, introduced alleles have largely displaced native alleles within the hybrid populations. Another marker (GNAT1) showed consistent heterozygote deficits in the wild, and this marker was associated with embryonic mortality in laboratory F2's. Other deviations from equilibrium expectations were idiosyncratic among breeding ponds, consistent with highly stochastic demographic effects. While most markers retain native and introduced alleles in expected proportions, strong selection appears to be eliminating native alleles at a smaller set of loci. Such rapid fixation of alleles is detectable only in recently formed hybrid zones, though it might be representative of dynamics that frequently occur in nature. These results underscore the variable and mosaic nature of hybrid genomes and illustrate the potency of recombination and selection in promoting variable, and often unpredictable genetic outcomes. Introgression of a few, strongly selected introduced alleles should not necessarily affect the conservation status of California Tiger Salamanders, but suggests that genetically pure populations of this endangered species will be difficult to maintain.

Rapid fixation of non-native alleles revealed by genome-wide SNP analysis of hybrid tiger salamanders

PubMed Central

Fitzpatrick, Benjamin M; Johnson, Jarrett R; Kump, D Kevin; Shaffer, H Bradley; Smith, Jeramiah J; Voss, S Randal

2009-01-01

Background Hybrid zones represent valuable opportunities to observe evolution in systems that are unusually dynamic and where the potential for the origin of novelty and rapid adaptation co-occur with the potential for dysfunction. Recently initiated hybrid zones are particularly exciting evolutionary experiments because ongoing natural selection on novel genetic combinations can be studied in ecological time. Moreover, when hybrid zones involve native and introduced species, complex genetic patterns present important challenges for conservation policy. To assess variation of admixture dynamics, we scored a large panel of markers in five wild hybrid populations formed when Barred Tiger Salamanders were introduced into the range of California Tiger Salamanders. Results At three of 64 markers, introduced alleles have largely displaced native alleles within the hybrid populations. Another marker (GNAT1) showed consistent heterozygote deficits in the wild, and this marker was associated with embryonic mortality in laboratory F2's. Other deviations from equilibrium expectations were idiosyncratic among breeding ponds, consistent with highly stochastic demographic effects. Conclusion While most markers retain native and introduced alleles in expected proportions, strong selection appears to be eliminating native alleles at a smaller set of loci. Such rapid fixation of alleles is detectable only in recently formed hybrid zones, though it might be representative of dynamics that frequently occur in nature. These results underscore the variable and mosaic nature of hybrid genomes and illustrate the potency of recombination and selection in promoting variable, and often unpredictable genetic outcomes. Introgression of a few, strongly selected introduced alleles should not necessarily affect the conservation status of California Tiger Salamanders, but suggests that genetically pure populations of this endangered species will be difficult to maintain. PMID:19630983

Diagnostic tests and neurology care for Medicare beneficiaries with seizures: differences across racial groups.

PubMed

Pisu, Maria; Richman, Joshua S; Martin, Roy C; Kim, Yongin; Kratt, Polly; Clements, Kay; Funkhouser, Ellen; Knowlton, Robert; Faught, Edward

2012-08-01

Seizures and epilepsy are common in older adults especially in some minorities. Despite the importance of medical care to maximize seizure control, little is known about its quality across racial groups. One indicator of quality care is the receipt of electroencephalograms (EEG), and magnetic resonance imaging (MRIs) or computer tomography scans (CTs) after a first seizure. Neurologists' care is also important, given associated diagnosis and treatment challenges in older patients. To examine seizure-related care in the year after a first seizure for Medicare beneficiaries by race. Retrospective administrative claims analysis for 186,547 beneficiaries with claims for seizure or epilepsy in 2003-2005. Logistic regressions determined the association between care and race (White, Asian, African and Native Americans) adjusting for beneficiary, seizure, and community factors. EEGs, CTs or MRIs, and neurology visits. About 60% received EEGs, 80% had MRIs or CT scans, and only 55.9% had an EEG and CT scan or an MRI. CT use (74%) was higher than MRI use (41%). About 79% had neurology visits. Compared with Whites, Native Americans were less likely to have neurology visits (66.9% vs. 78.8%; adjusted odds ratio: 0.72; 95% CI, 0.55-0.92). No clinically significant differences (>5%) were found for care received by other minorities compared with Whites. Medicare beneficiaries with new-onset seizures commonly visit a neurologist, with some groups lagging behind. Use of some diagnostic tests is less common. Studies should continue investigating the quality of medical care for older adults with seizures.

Can invasions occur without change? A comparison of G-matrices and selection in the peach-potato aphid, Myzus persicae

PubMed Central

Bacigalupe, Leonardo D; Barrientos, Karin; Beckerman, Andrew P; Carter, Mauricio J; Figueroa, Christian C; Foster, Stephen P; Moore, Allen J; Silva, Andrea X; Nespolo, Roberto F

2013-01-01

Most evolutionary research on biological invasions has focused on changes seen between the native and invaded range for a particular species. However, it is likely that species that live in human-modified habitats in their native range might have evolved specific adaptations to those environments, which increase the likelihood of establishment and spread in similar human-altered environments. From a quantitative genetic perspective, this hypothesis suggests that both native and introduced populations should reside at or near the same adaptive peak. Therefore, we should observe no overall changes in the G (genetic variance–covariance) matrices between native and introduced ranges, and stabilizing selection on fitness-related traits in all populations. We tested these predictions comparing three populations of the worldwide pest Myzus persicae from the Middle East (native range) and the UK and Chile (separately introduced ranges). In general, our results provide mixed support for this idea, but further comparisons of other species are needed. In particular, we found that there has been some limited evolution in the studied traits, with the Middle East population differing from the UK and Chilean populations. This was reflected in the structure of the G-matrices, in which Chile differed from both UK and Middle East populations. Furthermore, the amount of genetic variation was massively reduced in Chile in comparison with UK and Middle East populations. Finally, we found no detectable selection on any trait in the three populations, but clones from the introduced ranges started to reproduce later, were smaller, had smaller offspring, and had lower reproductive fitness than clones from the native range. PMID:24455140

Expression and purification of native and functional influenza A virus matrix 2 proton selective ion channel.

PubMed

Desuzinges Mandon, Elodie; Traversier, Aurélien; Champagne, Anne; Benier, Lorraine; Audebert, Stéphane; Balme, Sébastien; Dejean, Emmanuel; Rosa Calatrava, Manuel; Jawhari, Anass

2017-03-01

Influenza A virus displays one of the highest infection rates of all human viruses and therefore represents a severe human health threat associated with an important economical challenge. Influenza matrix protein 2 (M2) is a membrane protein of the viral envelope that forms a proton selective ion channel. Here we report the expression and native isolation of full length active M2 without mutations or fusions. The ability of the influenza virus to efficiently infect MDCK cells was used to express native M2 protein. Using a Calixarene detergents/surfactants based approach; we were able to solubilize most of M2 from the plasma membrane and purify it. The tetrameric form of native M2 was maintained during the protein preparation. Mass spectrometry shows that M2 was phosphorylated in its cytoplasmic tail (serine 64) and newly identifies an acetylation of the highly conserved Lysine 60. ELISA shows that solubilized and purified M2 was specifically recognized by M2 antibody MAB65 and was able to displace the antibody from M2 MDCK membranes. Using a bilayer voltage clamp measurement assay, we demonstrate a pH dependent proton selective ion channel activity. The addition of the M2 ion channel blocker amantadine allows a total inhibition of the channel activity, illustrating therefore the specificity of purified M2 activity. Taken together, this work shows the production and isolation of a tetrameric and functional native M2 ion channel that will pave the way to structural and functional characterization of native M2, conformational antibody development, small molecules compounds screening towards vaccine treatment. Copyright © 2016 Elsevier Inc. All rights reserved.

Environmentally induced development costs underlie fitness tradeoffs.

PubMed

Walter, Greg M; Wilkinson, Melanie J; Aguirre, J David; Blows, Mark W; Ortiz-Barrientos, Daniel

2018-06-01

Local adaptation can lead to genotype-by-environment interactions, which can create fitness tradeoffs in alternative environments, and govern the distribution of biodiversity across geographic landscapes. Exploring the ecological circumstances that promote the evolution of fitness tradeoffs requires identifying how natural selection operates and during which ontogenetic stages natural selection is strongest. When organisms disperse to areas outside their natural range, tradeoffs might emerge when organisms struggle to reach key life history stages, or alternatively, die shortly after reaching life history stages if there are greater risks of mortality associated with costs to developing in novel environments. We used multiple populations from four ecotypes of an Australian native wildflower (Senecio pinnatifolius) in reciprocal transplants to explore how fitness tradeoffs arise across ontogeny. We then assessed whether the survival probability for plants from native and foreign populations was contingent on reaching key developmental stages. We found that fitness tradeoffs emerged as ontogeny progressed when native plants were more successful than foreign plants at reaching seedling establishment and maturity. Native and foreign plants that failed to reach seedling establishment died at the same rate, but plants from foreign populations died quicker than native plants after reaching seedling establishment, and died quicker regardless of whether they reached sexual maturity or not. Development rates were similar for native and foreign populations, but changed depending on the environment. Together, our results suggest that natural selection for environment-specific traits early in life history created tradeoffs between contrasting environments. Plants from foreign populations were either unable to develop to seedling establishment, or they suffered increased mortality as a consequence of reaching seedling establishment. The observation of tradeoffs together with environmentally dependent changes in development rate suggest that foreign environments induce organisms to develop at a rate different from their native habitat, incurring consequences for lifetime fitness and population divergence. © 2018 by the Ecological Society of America.

Confronting the Impact of Alcohol Labeling and Marketing on Native American Health and Culture. Hearing before the Select Committee on Children, Youth and Families. House of Representatives, One Hundred Second Congress, Second Session.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. House Select Committee on Children, Youth, and Families.

A congressional hearing examined the effects of alcohol labeling and marketing on Native American health and culture. The focus of the hearing was on "Crazy Horse" malt liquor, a product named for the spiritual and political leader of the Native American Sioux. Following opening remarks by presiding committee chairwoman, Patricia…

Development of Native American Culture and Art--Part 3. To Promote the Development of Native American Culture and Art. Hearing Before the Select Committee on Indian Affairs, United States Senate, Ninety-Seventh Congress, First Session on S. 792.

ERIC Educational Resources Information Center

Congress of the U.S., Washington, DC. Senate Select Committee on Indian Affairs.

The Select Committee on Indian Affairs met July 29, 1981 to hear testimony concerning S. 792, a bill to provide for the establishment of a national institute to preserve, revitalize, and disseminate Indian art and culture. Bill S. 792 was endorsed by senators from Oregon and Hawaii and, with certain reservations, by representatives of eight Indian…

Selective desulfurization of cysteine in the presence of Cys(Acm) in polypeptides obtained by native chemical ligation.

PubMed

Pentelute, Brad L; Kent, Stephen B H

2007-02-15

Increased versatility for the synthesis of proteins and peptides by native chemical ligation requires the ability to ligate at positions other than Cys. Here, we report that Raney nickel can be used under standard conditions for the selective desulfurization of Cys in the presence of Cys(Acm). This simple and practical tactic enables the more common Xaa-Ala junctions to be used as ligation sites for the chemical synthesis of Cys-containing peptides and proteins. [reaction: see text].

32 CFR 1645.6 - Considerations relevant to granting or denying a claim for Class 4-D.

Code of Federal Regulations, 2010 CFR

2010-07-01

... Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.6 Considerations relevant... registrant is requesting classification in Class 4-D because he is a regular minister of religion or because he is a duly ordained minister of religion. (b) If the registrant claims to be a duly ordained...

Too Much of a Good Thing: User Leadership at TPAC

ERIC Educational Resources Information Center

Connelly, Brett; Dalton, Tashia; Murphy, Derrick; Rosales, Daniel; Sudlow, Daniel; Havelka, Douglas

2016-01-01

TPAC is a small third party health claims business that was seeking avenues for revenue growth and opportunities to increase efficiency. One course of action that management selected to achieve these goals was a change in the software application used to process claims. The new application was adopted to increase the speed and accuracy of claims…

32 CFR 1645.6 - Considerations relevant to granting or denying a claim for Class 4-D.

Code of Federal Regulations, 2014 CFR

2014-07-01

... Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.6 Considerations relevant... registrant is requesting classification in Class 4-D because he is a regular minister of religion or because he is a duly ordained minister of religion. (b) If the registrant claims to be a duly ordained...

32 CFR 1645.6 - Considerations relevant to granting or denying a claim for Class 4-D.

Code of Federal Regulations, 2011 CFR

2011-07-01

... Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.6 Considerations relevant... registrant is requesting classification in Class 4-D because he is a regular minister of religion or because he is a duly ordained minister of religion. (b) If the registrant claims to be a duly ordained...

32 CFR 1645.6 - Considerations relevant to granting or denying a claim for Class 4-D.

Code of Federal Regulations, 2013 CFR

2013-07-01

... Defense SELECTIVE SERVICE SYSTEM CLASSIFICATION OF MINISTERS OF RELIGION § 1645.6 Considerations relevant... registrant is requesting classification in Class 4-D because he is a regular minister of religion or because he is a duly ordained minister of religion. (b) If the registrant claims to be a duly ordained...

Adaptive responses to cool climate promotes persistence of a non-native lizard

PubMed Central

While, Geoffrey M.; Williamson, Joseph; Prescott, Graham; Horváthová, Terézia; Fresnillo, Belén; Beeton, Nicholas J.; Halliwell, Ben; Michaelides, Sozos; Uller, Tobias

2015-01-01

Successful establishment and range expansion of non-native species often require rapid accommodation of novel environments. Here, we use common-garden experiments to demonstrate parallel adaptive evolutionary response to a cool climate in populations of wall lizards (Podarcis muralis) introduced from southern Europe into England. Low soil temperatures in the introduced range delay hatching, which generates directional selection for a shorter incubation period. Non-native lizards from two separate lineages have responded to this selection by retaining their embryos for longer before oviposition—hence reducing the time needed to complete embryogenesis in the nest—and by an increased developmental rate at low temperatures. This divergence mirrors local adaptation across latitudes and altitudes within widely distributed species and suggests that evolutionary responses to climate can be very rapid. When extrapolated to soil temperatures encountered in nests within the introduced range, embryo retention and faster developmental rate result in one to several weeks earlier emergence compared with the ancestral state. We show that this difference translates into substantial survival benefits for offspring. This should promote short- and long-term persistence of non-native populations, and ultimately enable expansion into areas that would be unattainable with incubation duration representative of the native range. PMID:25694617

Perception and Production of Singleton and Geminate Stops in Japanese: Implications for the Theory of Acoustic Invariance.

PubMed

Amano, Shigeaki; Hirata, Y

2015-01-01

The theory of relational acoustic invariance claims that there are stable acoustic properties in speech signals that correspond to a phonological feature, and that the perception system utilizes these acoustic properties for stable perception of a phoneme. The present study examines whether such an invariance exists in native listeners' perception of Japanese singleton and geminate stops despite variability in speaking rate and word length, and whether this perception corresponds to production. Native Japanese listeners identified singleton and geminate stops in continua of 3- and 4-mora words spoken at different speaking rates. Results indicated that the perception boundary is well predicted by a linear function with two variables: durations of stop closure and the (C)V(C)CV portion (with the contrasting stops underlined) of the 3- and 4-mora words. In addition, these two variables were in a consistent relationship for both perception and production of words containing 2-4 moras. The results support the relational acoustic invariance theory. © 2015 S. Karger AG, Basel.

Categorical Perception Beyond the Basic Level: The Case of Warm and Cool Colors.

PubMed

Holmes, Kevin J; Regier, Terry

2017-05-01

Categories can affect our perception of the world, rendering between-category differences more salient than within-category ones. Across many studies, such categorical perception (CP) has been observed for the basic-level categories of one's native language. Other research points to categorical distinctions beyond the basic level, but it does not demonstrate CP for such distinctions. Here we provide such a demonstration. Specifically, we show CP in English speakers for the non-basic distinction between "warm" and "cool" colors, claimed to represent the earliest stage of color lexicon evolution. Notably, the advantage for discriminating colors that straddle the warm-cool boundary was restricted to the right visual field-the same behavioral signature previously observed for basic-level categories. This pattern held in a replication experiment with increased power. Our findings show that categorical distinctions beyond the basic-level repertoire of one's native language are psychologically salient and may be spontaneously accessed during normal perceptual processing. Copyright © 2016 Cognitive Science Society, Inc.

Virtue ethics and the selection of children with impairments: a reply to Rosalind McDougall.

PubMed

Saenz, Carla

2010-11-01

In 'Parental Virtues: A New Way of Thinking about the Morality of Reproductive Actions' Rosalind McDougall proposes a virtue-based framework to assess the morality of child selection. Applying the virtue-based account to the selection of children with impairments does not lead, according to McDougall, to an unequivocal answer to the morality of selecting impaired children. In 'Impairment, Flourishing, and the Moral Nature of Parenthood,' she also applies the virtue-based account to the discussion of child selection, and claims that couples with an impairment are morally justified in selecting a child with the same impairment. This claim, she maintains, reveals that the flourishing of a child should be understood as requiring environment-specific characteristics. I argue that McDougall's argument begs the question. More importantly, it does not do justice to virtue ethics. I also question to what extent a virtue ethics framework can be successfully applied to discussions about the moral permissibility of reproductive actions. © 2009 Blackwell Publishing Ltd.

Virtue Ethics and the Selection of Children with Impairments A Reply to Rosalind McDougall

PubMed Central

Saenz, Carla

2009-01-01

In “Parental Virtues: A New Way of Thinking about the Morality of Reproductive Actions” Rosalind McDougall proposes a virtue-based framework to assess the morality of child selection. Applying the virtue-based account to the selection of children with impairments does not lead, according to McDougall, to an unequivocal answer to the morality of selecting impaired children. In “Impairment, Flourishing, and the Moral Nature of Parenthood,” she also applies the virtue-based account to the discussion of child selection, and claims that couples with an impairment are morally justified in selecting a child with the same impairment. This claim, she maintains, reveals that the flourishing of a child should be understood as requiring environment-specific characteristics. I argue that McDougall’s argument begs the question. More importantly, it does not do justice to virtue ethics. I also question to what extent a virtue ethics framework can be successfully applied to discussions about the moral permissibility of reproductive actions. PMID:19508307

Processes and patterns of interaction as units of selection: An introduction to ITSNTS thinking.

PubMed

Doolittle, W Ford; Inkpen, S Andrew

2018-04-17

Many practicing biologists accept that nothing in their discipline makes sense except in the light of evolution, and that natural selection is evolution's principal sense-maker. But what natural selection actually is (a force or a statistical outcome, for example) and the levels of the biological hierarchy (genes, organisms, species, or even ecosystems) at which it operates directly are still actively disputed among philosophers and theoretical biologists. Most formulations of evolution by natural selection emphasize the differential reproduction of entities at one or the other of these levels. Some also recognize differential persistence, but in either case the focus is on lineages of material things: even species can be thought of as spatiotemporally restricted, if dispersed, physical beings. Few consider-as "units of selection" in their own right-the processes implemented by genes, cells, species, or communities. "It's the song not the singer" (ITSNTS) theory does that, also claiming that evolution by natural selection of processes is more easily understood and explained as differential persistence than as differential reproduction. ITSNTS was formulated as a response to the observation that the collective functions of microbial communities (the songs) are more stably conserved and ecologically relevant than are the taxa that implement them (the singers). It aims to serve as a useful corrective to claims that "holobionts" (microbes and their animal or plant hosts) are aggregate "units of selection," claims that often conflate meanings of that latter term. But ITSNS also seems broadly applicable, for example, to the evolution of global biogeochemical cycles and the definition of ecosystem function.

The phytoremediation potential of native plants on New Zealand dairy farms.

PubMed

Hahner, Jason L; Robinson, Brett H; Hong-Tao, Zhong; Dickinson, Nicholas M

2014-01-01

Ecological restoration of marginal land and riparian zones in agricultural landscapes in New Zealand enhances the provision of above-ground ecosystem services. We investigated whether native endemic plant assemblages have remediation potential, through modifying soil nutrient and trace element mobility. Analysis of native plant foliage in situ indicated that selective uptake of a range of commonly deficient trace elements including Zn, B, Cu, Mn and Co could provide a browse crop to avoid deficiencies of these elements in livestock, although some native plants may enhance the risk of Mo and Cd toxicity. Native plant rhizospheres were found to modify soil physico-chemistry and are likely to influence lateral and vertical fluxes of chemical elements in drainage waters. Native plants on marginal land in agricultural landscapes could add value to dairy production systems whilst helping to resolve topical environmental issues.

SOIL QUALITY RECOVERY IN PREVIOUSLY FARMED FIELDS SEEDED TO PERENNIAL WARM SEASON NATIVE GRASS

EPA Science Inventory

A study of twelve Conservation Reserve Program sites in northeastern Kansas was conducted to determine native grass species and selected soil textures influence on soil quality recovery.
Plant productivity, plant carbon and nitrogen concentrations, total soil nitrogen and car...

Quantitative Trait Loci Mapping of Western Corn Rootworm (Coleoptera: Chrysomelidae) Host Plant Resistance in Two Populations of Doubled Haploid Lines in Maize (Zea mays L.).

PubMed

Bohn, Martin O; Marroquin, Juan J; Flint-Garcia, Sherry; Dashiell, Kenton; Willmot, David B; Hibbard, Bruce E

2018-02-09

Over the last 70 yr, more than 12,000 maize accessions have been screened for their level of resistance to western corn rootworm, Diabrotica virgifera virgifera (LeConte; Coleoptera: Chrysomelidae), larval feeding. Less than 1% of this germplasm was selected for initiating recurrent selection or other breeding programs. Selected genotypes were mostly characterized by large root systems and superior root regrowth after root damage caused by western corn rootworm larvae. However, no hybrids claiming native (i.e., host plant) resistance to western corn rootworm larval feeding are currently commercially available. We investigated the genetic basis of western corn rootworm resistance in maize materials with improved levels of resistance using linkage disequilibrium mapping approaches. Two populations of topcrossed doubled haploid maize lines (DHLs) derived from crosses between resistant and susceptible maize lines were evaluated for their level of resistance in three to four different environments. For each DHL topcross an average root damage score was estimated and used for quantitative trait loci (QTL) analysis. We found genomic regions contributing to western corn rootworm resistance on all maize chromosomes, except for chromosome 4. Models fitting all QTL simultaneously explained about 30 to 50% of the genotypic variance for root damage scores in both mapping populations. Our findings confirm the complex genetic structure of host plant resistance against western corn rootworm larval feeding in maize. Interestingly, three of these QTL regions also carry genes involved in ascorbate biosynthesis, a key compound we hypothesize is involved in the expression of western corn rootworm resistance. © The Author(s) 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Understanding the types of fraud in claims to South African medical schemes.

PubMed

Legotlo, T G; Mutezo, A

2018-03-28

Medical schemes play a significant role in funding private healthcare in South Africa (SA). However, the sector is negatively affected by the high rate of fraudulent claims. To identify the types of fraudulent activities committed in SA medical scheme claims. A cross-sectional qualitative study was conducted, adopting a case study strategy. A sample of 15 employees was purposively selected from a single medical scheme administration company in SA. Semi-structured interviews were conducted to collect data from study participants. A thematic analysis of the data was done using ATLAS.ti software (ATLAS.ti Scientific Software Development, Germany). The study population comprised the 17 companies that administer medical schemes in SA. Data were collected from 15 study participants, who were selected from the medical scheme administrator chosen as a case study. The study found that medical schemes were defrauded in numerous ways. The perpetrators of this type of fraud include healthcare service providers, medical scheme members, employees, brokers and syndicates. Medical schemes are mostly defrauded by the submission of false claims by service providers and syndicates. Fraud committed by medical scheme members encompasses the sharing of medical scheme benefits with non-members (card farming) and non-disclosure of pre-existing conditions at the application stage. The study concluded that perpetrators of fraud have found several ways of defrauding SA medical schemes regarding claims. Understanding and identifying the types of fraud events facing medical schemes is the initial step towards establishing methods to mitigate this risk. Future studies should examine strategies to manage fraudulent medical scheme claims.

Can a native rodent species limit the invasive potential of a non-native rodent species in tropical agroforest habitats?

PubMed

Stuart, Alexander M; Prescott, Colin V; Singleton, Grant R

2016-06-01

Little is known about native and non-native rodent species interactions in complex tropical agroecosystems. We hypothesised that the native non-pest rodent Rattus everetti may be competitively dominant over the invasive pest rodent Rattus tanezumi within agroforests. We tested this experimentally by using pulse removal for three consecutive months to reduce populations of R. everetti in agroforest habitat, and assessed over 6 months the response of R. tanezumi and other rodent species. Following removal, R. everetti individuals rapidly immigrated into removal sites. At the end of the study period, R. tanezumi were larger and there was a significant shift in their microhabitat use with respect to the use of ground vegetation cover following the perturbation of R. everetti. Irrespective of treatment, R. tanezumi selected microhabitat with less tree canopy cover, indicative of severely disturbed habitat, whereas R. everetti selected microhabitat with a dense canopy. Our results suggest that sustained habitat disturbance in agroforests favours R. tanezumi, while the regeneration of agroforests towards a more natural state would favour native species and may reduce pest pressure in adjacent crops. In addition, the rapid recolonisation of R. everetti suggests this species would be able to recover from non-target impacts of short-term rodent pest control. © 2015 Society of Chemical Industry. © 2015 Society of Chemical Industry.

Perceiving non-native speech: Word segmentation

NASA Astrophysics Data System (ADS)

Mondini, Michèle; Miller, Joanne L.

2004-05-01

One important source of information listeners use to segment speech into discrete words is allophonic variation at word junctures. Previous research has shown that non-native speakers impose their native-language phonetic norms on their second language; as a consequence, non-native speech may (in some cases) exhibit altered patterns of allophonic variation at word junctures. We investigated the perceptual consequences of this for word segmentation by presenting native-English listeners with English word pairs produced either by six native-English speakers or six highly fluent, native-French speakers of English. The target word pairs had contrastive word juncture involving voiceless stop consonants (e.g., why pink/wipe ink; gray ties/great eyes; we cash/weak ash). The task was to identify randomized instances of each individual target word pair (as well as control pairs) by selecting one of four possible choices (e.g., why pink, wipe ink, why ink, wipe pink). Overall, listeners were more accurate in identifying target word pairs produced by the native-English speakers than by the non-native English speakers. These findings suggest that one contribution to the processing cost associated with listening to non-native speech may be the presence of altered allophonic information important for word segmentation. [Work supported by NIH/NIDCD.

Current and future developments in patents for quantitative trait loci in dairy cattle.

PubMed

Weller, Joel I

2007-01-01

Many studies have proposed that rates of genetic gain in dairy cattle can be increased by direct selection on the individual quantitative loci responsible for the genetic variation in these traits, or selection on linked genetic markers. The development of DNA-level genetic markers has made detection of QTL nearly routine in all major livestock species. The studies that attempted to detect genes affecting quantitative traits can be divided into two categories: analysis of candidate genes, and genome scans based on within-family genetic linkage. To date, 12 patent cooperative treaty (PCT) and US patents have been registered for DNA sequences claimed to be associated with effects on economic traits in dairy cattle. All claim effects on milk production, but other traits are also included in some of the claims. Most of the sequences found by the candidate gene approach are of dubious validity, and have been repeated in only very few independent studies. The two missense mutations on chromosomes 6 and 14 affecting milk concentration derived from genome scans are more solidly based, but the claims are also disputed. A few PCT in dairy cattle are commercialized as genetic tests where commercial dairy farmers are the target market.

Curriculum Guidelines: Native Hawaiian Curriculum Development Project.

ERIC Educational Resources Information Center

Kawakami, Alice J.; Aton, Kanani; Glendon, Crystal; Stewart, Roxane

The Na'imiloa (seeker of knowledge) program provides educational enrichment opportunities to gifted underachieving Native Hawaiian high school students. Developed by the University of Hawaii at Hilo and selected high schools, the program was designed to build upon students' talents, develop their self-esteem, and develop an awareness and…

Growing Up Native American. An Anthology.

ERIC Educational Resources Information Center

Riley, Patricia, Ed.

This anthology contains 22 essays and fictional writings about childhood by well-known Native American writers of the United States and Canada, from the 19th century to the 1990s. Selections include short stories, excerpts from novels, autobiographical sketches, and essays about the relationship between language and culture, family relationships,…

A Correlation Study of Secondary Education and Postsecondary Outcomes for Native Americans with Disabilities

ERIC Educational Resources Information Center

Graham, Deborah J.

2016-01-01

This nonexperimental quantitative correlation study examined relationships between select special education and standardized testing variables for a purposive homogeneous sample of Arizona secondary school districts with Native American populations, and the archival records for students with disabilities postsecondary outcomes between 2012 and…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gagne, Roderick B.; Hogan, J. Derek; McIntyre, Peter B.

1. Co-introductions of non-native parasites with non-native hosts can be a major driver of disease emergence in native species, but the conditions that promote the establishment and spread of nonnative parasites remain poorly understood. Here, we characterise the infection of a native host species by a non-native parasite relative to the distribution and density of the original non-native host species and a suite of organismal and environmental factors that have been associated with parasitism, but not commonly considered within a single system. 2. We examined the native Hawaiian goby Awaous stamineus across 23 catchments on five islands for infection bymore » the non-native nematode parasite Camallanus cotti. We used model selection to test whether parasite infection was associated with the genetic diversity, size and population density of native hosts, the distribution and density of non-native hosts, land use and water quality. 3. We found that the distribution of non-native C. cotti parasites has become decoupled from the non-native hosts that were primary vectors of introduction to the Hawaiian Islands. Although no single intrinsic or extrinsic factor was identified that best explains parasitism of A. stamineus by C. cotti, native host size, population density and water quality were consistently identified as influencing parasite intensity and prevalence. 4. The introduction of non-native species can indirectly influence native species through infection of co-introduced parasites. Here, we show that the effects of enemy addition can extend beyond the range of non-native hosts through the independent spread of non-native parasites. This suggests that control of non-native hosts is not sufficient to halt the spread of introduced parasites. Furthermore, designing importation regulations to prevent host parasite co-introductions can promote native species conservation, even in remote areas that may not seem susceptible to human influence.« less

Division of Attention Relative to Response Between Attended and Unattended Stimuli.

ERIC Educational Resources Information Center

Kantowitz, Barry H.

Research was conducted to investigate two general classes of human attention models, early-selection models which claim that attentional selecting precedes memory and meaning extraction mechanisms, and late-selection models which posit the reverse. This research involved two components: (1) the development of simple, efficient, computer-oriented…

Introduced species as evolutionary traps

USGS Publications Warehouse

Schlaepfer, Martin A.; Sherman, P.W.; Blossey, B.; Runge, M.C.

2005-01-01

Invasive species can alter environments in such a way that normal behavioural decision-making rules of native species are no longer adaptive. The evolutionary trap concept provides a useful framework for predicting and managing the impact of harmful invasive species. We discuss how native species can respond to changes in their selective regime via evolution or learning. We also propose novel management strategies to promote the long-term co-existence of native and introduced species in cases where the eradication of the latter is either economically or biologically unrealistic.

Nutrition-related claims on children's cereals: what do they mean to parents and do they influence willingness to buy?

PubMed

Harris, Jennifer L; Thompson, Jacqueline M; Schwartz, Marlene B; Brownell, Kelly D

2011-12-01

To examine parents' beliefs about the meaning of common front-of-package nutrition-related claims on children's cereals and determine whether the claims would make them more willing to buy the cereals. Parents viewed images of box fronts for children's cereals of below-average nutritional quality, as assessed by a validated nutrient profiling model. These boxes featured various nutrition-related claims including 'supports your child's immunity', 'whole grain', 'fibre', 'calcium and vitamin D' and 'organic'. Participants were provided possible meanings for these claims and asked to select any that applied with the option to write in additional meanings. They also indicated how the claim would affect their willingness to buy the product. Online survey. Parents with children between the ages of 2 and 11 years (n 306) recruited through an online panel. The majority of parents misinterpreted the meaning of claims commonly used on children's cereals. They inferred that cereals with claims were more nutritious overall and might provide specific health-related benefits for their children; and these beliefs predicted greater willingness to buy the cereals. These findings indicate that common front-of-package nutrition-related claims are potentially misleading, especially when placed on products with high levels of nutrients to limit (e.g. sugar, sodium) and low levels of other nutrients to encourage (e.g. fibre, protein). Additional regulation is needed to protect consumers in the USA.

Patient-reported outcomes to support medical product labeling claims: FDA perspective.

PubMed

Patrick, Donald L; Burke, Laurie B; Powers, John H; Scott, Jane A; Rock, Edwin P; Dawisha, Sahar; O'Neill, Robert; Kennedy, Dianne L

2007-01-01

This article concerns development and use of patient-reported outcomes (PROs) in clinical trials to evaluate medical products. A PRO is any report coming directly from patients, without interpretation by physicians or others, about how they function or feel in relation to a health condition and its therapy. PRO instruments are used to measure these patient reports. PROs provide a unique perspective on medical therapy, because some effects of a health condition and its therapy are known only to patients. Properly developed and evaluated PRO instruments also have the potential to provide more sensitive and specific measurements of the effects of medical therapies, thereby increasing the efficiency of clinical trials that attempt to measure the meaningful treatment benefits of those therapies. Poorly developed and evaluated instruments may provide misleading conclusions or data that cannot be used to support product labeling claims. We review selected major challenges from Food and Drug Administration's perspective in using PRO instruments, measures, and end points to support treatment benefit claims in product labeling. These challenges highlight the need for sponsors to formulate desired labeling claim(s) prospectively, to acquire and document information needed to support these claim(s), and to identify existing instruments or develop new and more appropriate PRO instruments for evaluating treatment benefit in the defined population in which they will seek claims.

The art and science of weed mapping

USGS Publications Warehouse

Barnett, David T.; Stohlgren, Thomas J.; Jarnevich, Catherine S.; Chong, Geneva W.; Ericson, Jenny A.; Davern, Tracy R.; Simonson, Sara E.

2007-01-01

Land managers need cost-effective and informative tools for non-native plant species management. Many local, state, and federal agencies adopted mapping systems designed to collect comparable data for the early detection and monitoring of non-native species. We compared mapping information to statistically rigorous, plot-based methods to better understand the benefits and compatibility of the two techniques. Mapping non-native species locations provided a species list, associated species distributions, and infested area for subjectively selected survey sites. The value of this information may be compromised by crude estimates of cover and incomplete or biased estimations of species distributions. Incorporating plot-based assessments guided by a stratified-random sample design provided a less biased description of non-native species distributions and increased the comparability of data over time and across regions for the inventory, monitoring, and management of non-native and native plant species.

Patent disclosure requirements for therapeutic antibody patents.

PubMed

De Luca, Carmela; Trifonova, Anastassia

2017-08-01

Therapeutic antibodies have grown to become an important product class within the biopharmaceutical market. A prerequisite to their commercialization is adequate patent protection. Disclosure requirements and the types of claims available in different jurisdictions can impact the scope of protection available for antibodies. Areas covered: A comparative review of statutory bases, patent office practices and selected decisions in Canada, the United States and the United Kingdom related to disclosure requirements is provided. Expert opinion: Differences in disclosure requirements exist in different jurisdictions which can impact the type of claims obtained and their survival when attacked in litigation. Including a wide variety of claim types is a key strategy to ensuring therapeutic antibodies are adequately protected. Method of use claims may provide advantages and broader protection in some circumstances and should also be considered.

Adaptive responses to cool climate promotes persistence of a non-native lizard.

PubMed

While, Geoffrey M; Williamson, Joseph; Prescott, Graham; Horváthová, Terézia; Fresnillo, Belén; Beeton, Nicholas J; Halliwell, Ben; Michaelides, Sozos; Uller, Tobias

2015-03-22

Successful establishment and range expansion of non-native species often require rapid accommodation of novel environments. Here, we use common-garden experiments to demonstrate parallel adaptive evolutionary response to a cool climate in populations of wall lizards (Podarcis muralis) introduced from southern Europe into England. Low soil temperatures in the introduced range delay hatching, which generates directional selection for a shorter incubation period. Non-native lizards from two separate lineages have responded to this selection by retaining their embryos for longer before oviposition--hence reducing the time needed to complete embryogenesis in the nest--and by an increased developmental rate at low temperatures. This divergence mirrors local adaptation across latitudes and altitudes within widely distributed species and suggests that evolutionary responses to climate can be very rapid. When extrapolated to soil temperatures encountered in nests within the introduced range, embryo retention and faster developmental rate result in one to several weeks earlier emergence compared with the ancestral state. We show that this difference translates into substantial survival benefits for offspring. This should promote short- and long-term persistence of non-native populations, and ultimately enable expansion into areas that would be unattainable with incubation duration representative of the native range. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

Southwestern Native American Studies: A Selected Bibliography.

ERIC Educational Resources Information Center

Stabler, Karen, Comp.

Conducting research in the field of Native American studies requires the use of many different materials in the library. This guide provides a bibliography of useful tools as well as a basic strategy to follow when researching the topic. The types of documents listed include: dictionaries and encyclopedias, guides and handbooks, journal articles,…

Growing media [Chapter 5

Treesearch

Douglass F. Jacobs; Thomas D. Landis; Tara Luna

2009-01-01

Selecting the proper growing medium is one of the most important considerations in nursery plant production. A growing medium can be defined as a substance through which roots grow and extract water and nutrients. In native plant nurseries, a growing medium can consist of native soil but is more commonly an "artificial soil" composed of materials such as peat...

Quantifying soil profile change caused by land use in central Missouri loess hillslopes

Treesearch

Samuel J. Indorante; John M. Kabrick; Brad D. Lee; Jon M. Maatta

2014-01-01

Three major challenges are present when studying anthropogenic impacts on soil profile properties: (i) site selection; (ii) sampling and modeling native and cultivated soil-landscape relationships; and (iii) graphically and statistically comparing native and cultivated sites to model soil profile changes. This study addressed those challenges by measuring and modeling...

Indian - Inuit - Metis: Selected Bibliography.

ERIC Educational Resources Information Center

Robinson, Paul

Designed to show that native authorship is flourishing, that excellent books by non-native writers are available, and that many small and a few large companies publish these works, this bibliography of more than 200 fiction and non-fiction listings written between 1966 and 1979 contains: (1) non-fiction and fiction books and materials by native…

Planning the future's forests with assisted migration

Treesearch

Mary I. Williams; R. Kasten Dumroese

2014-01-01

Studies show that changes in climate may exceed plant adaptation and migration. The mismatch in rates between climate change and plant adaptation and migration will pose significant challenges for practitioners that select, grow, and outplant native tree species. Native tree species and populations that are planted today must meet the climatic challenges that they will...

Selectivity in L1 Attrition: Differential Object Marking in Spanish Near-Native Speakers of English

ERIC Educational Resources Information Center

Chamorro, Gloria; Sturt, Patrick; Sorace, Antonella

2016-01-01

Previous research has shown L1 attrition to be restricted to structures at the interfaces between syntax and pragmatics, but not to occur with syntactic properties that do not involve such interfaces ("Interface Hypothesis", Sorace and Filiaci in "Anaphora resolution in near-native speakers of Italian." "Second Lang…

Negative Stereotypes Deconstructed and Transformed in the Experience of Native American Academics

ERIC Educational Resources Information Center

Dvorakova, Antonie

2018-01-01

This qualitative interdisciplinary study explored the responses of Native American academics to selected contingencies of their tribal identities. Negative stereotypes emerged as an important topic from the narratives of 20 male and 20 female tribal academics in a variety of disciplines whom the author interviewed at 28 universities across the…

Closing the Math Gap of Native American Students Identified as Learning Disabled

ERIC Educational Resources Information Center

Hankes, Judith; Skoning, Stacey; Fast, Gerald; Mason-Williams, Loretta

2013-01-01

This article serves as an overview of activities and selected assessment findings of a three-year research study titled, Closing the Mathematics Achievement Gap of Native American Students Identified as Learning Disabled Project (CMAG Project). Methods used were problem-based, consistent with those of Cognitively Guided Instruction, and culturally…

A priori assessment of reintroduction strategies for a native ungulate: Using HexSim to guide release site selection

EPA Science Inventory

Reintroduction of native species to unoccupied portions of their historical range is a common management strategy to enhance the future viability of animal populations. This approach has met with mixed success, due to unforeseen impacts caused by human or other factors. Some of t...

Nonnegative constraint analysis of key fluorophores within human breast cancer using native fluorescence spectroscopy excited by selective wavelength of 300 nm

NASA Astrophysics Data System (ADS)

Pu, Yang; Sordillo, Laura A.; Alfano, Robert R.

2015-03-01

Native fluorescence spectroscopy offers an important role in cancer discrimination. It is widely acknowledged that the emission spectrum of tissue is a superposition of spectra of various salient fluorophores. In this study, the native fluorescence spectra of human cancerous and normal breast tissues excited by selected wavelength of 300 nm are used to investigate the key building block fluorophores: tryptophan and reduced nicotinamide adenine dinucleotide (NADH). The basis spectra of these key fluorophores' contribution to the tissue emission spectra are obtained by nonnegative constraint analysis. The emission spectra of human cancerous and normal tissue samples are projected onto the fluorophore spectral subspace. Since previous studies indicate that tryptophan and NADH are key fluorophores related with tumor evolution, it is essential to obtain their information from tissue fluorescence but discard the redundancy. To evaluate the efficacy of for cancer detection, linear discriminant analysis (LDA) classifier is used to evaluate the sensitivity, and specificity. This research demonstrates that the native fluorescence spectroscopy measurements are effective to detect changes of fluorophores' compositions in tissues due to the development of cancer.

Data linkage of inpatient hospitalization and workers' claims data sets to characterize occupational falls.

PubMed

Bunn, Terry L; Slavova, Svetla; Bathke, Arne

2007-07-01

The identification of industry, occupation, and associated injury costs for worker falls in Kentucky have not been fully examined. The purpose of this study was to determine the associations between industry and occupation and 1) hospitalization length of stay; 2) hospitalization charges; and 3) workers' claims costs in workers suffering falls, using linked inpatient hospitalization discharge and workers' claims data sets. Hospitalization cases were selected with ICD-9-CM external cause of injury codes for falls and payer code of workers' claims for years 2000-2004. Selection criteria for workers'claims cases were International Association of Industrial Accident Boards and Commissions Electronic Data Interchange Nature (IAIABCEDIN) injuries coded as falls and/or slips. Common data variables between the two data sets such as date of birth, gender, date of injury, and hospital admission date were used to perform probabilistic data linkage using LinkSolv software. Statistical analysis was performed with non-parametric tests. Construction falls were the most prevalent for male workers and incurred the highest hospitalization and workers' compensation costs, whereas most female worker falls occurred in the services industry. The largest percentage of male worker falls was from one level to another, while the largest percentage of females experienced a fall, slip, or trip (not otherwise classified). When male construction worker falls were further analyzed, laborers and helpers had longer hospital stays as well as higher total charges when the worker fell from one level to another. Data linkage of hospitalization and workers' claims falls data provides additional information on industry, occupation, and costs that are not available when examining either data set alone.

Asymmetric mutations in the tetrameric R67 dihydrofolate reductase reveal high tolerance to active-site substitutions.

PubMed

Ebert, Maximilian C C J C; Morley, Krista L; Volpato, Jordan P; Schmitzer, Andreea R; Pelletier, Joelle N

2015-04-01

Type II R67 dihydrofolate reductase (DHFR) is a bacterial plasmid-encoded enzyme that is intrinsically resistant to the widely-administered antibiotic trimethoprim. R67 DHFR is genetically and structurally unrelated to E. coli chromosomal DHFR and has an unusual architecture, in that four identical protomers form a single symmetrical active site tunnel that allows only one substrate binding/catalytic event at any given time. As a result, substitution of an active-site residue has as many as four distinct consequences on catalysis, constituting an atypical model of enzyme evolution. Although we previously demonstrated that no single residue of the native active site is indispensable for function, library selection here revealed a strong bias toward maintenance of two native protomers per mutated tetramer. A variety of such "half-native" tetramers were shown to procure native-like catalytic activity, with similar KM values but kcat values 5- to 33-fold lower, illustrating a high tolerance for active-site substitutions. The selected variants showed a reduced thermal stability (Tm ∼12°C lower), which appears to result from looser association of the protomers, but generally showed a marked increase in resilience to heat denaturation, recovering activity to a significantly greater extent than the variant with no active-site substitutions. Our results suggest that the presence of two native protomers in the R67 DHFR tetramer is sufficient to provide native-like catalytic rate and thus ensure cellular proliferation. © 2014 The Protein Society.

Detecting the Population Structure and Scanning for Signatures of Selection in Horses (Equus caballus) From Whole-Genome Sequencing Data

PubMed Central

Zhang, Cheng; Ni, Pan; Ahmad, Hafiz Ishfaq; Gemingguli, M; Baizilaitibei, A; Gulibaheti, D; Fang, Yaping; Wang, Haiyang; Asif, Akhtar Rasool; Xiao, Changyi; Chen, Jianhai; Ma, Yunlong; Liu, Xiangdong; Du, Xiaoyong; Zhao, Shuhong

2018-01-01

Animal domestication gives rise to gradual changes at the genomic level through selection in populations. Selective sweeps have been traced in the genomes of many animal species, including humans, cattle, and dogs. However, little is known regarding positional candidate genes and genomic regions that exhibit signatures of selection in domestic horses. In addition, an understanding of the genetic processes underlying horse domestication, especially the origin of Chinese native populations, is still lacking. In our study, we generated whole genome sequences from 4 Chinese native horses and combined them with 48 publicly available full genome sequences, from which 15 341 213 high-quality unique single-nucleotide polymorphism variants were identified. Kazakh and Lichuan horses are 2 typical Asian native breeds that were formed in Kazakh or Northwest China and South China, respectively. We detected 1390 loss-of-function (LoF) variants in protein-coding genes, and gene ontology (GO) enrichment analysis revealed that some LoF-affected genes were overrepresented in GO terms related to the immune response. Bayesian clustering, distance analysis, and principal component analysis demonstrated that the population structure of these breeds largely reflected weak geographic patterns. Kazakh and Lichuan horses were assigned to the same lineage with other Asian native breeds, in agreement with previous studies on the genetic origin of Chinese domestic horses. We applied the composite likelihood ratio method to scan for genomic regions showing signals of recent selection in the horse genome. A total of 1052 genomic windows of 10 kB, corresponding to 933 distinct core regions, significantly exceeded neutral simulations. The GO enrichment analysis revealed that the genes under selective sweeps were overrepresented with GO terms, including “negative regulation of canonical Wnt signaling pathway,” “muscle contraction,” and “axon guidance.” Frequent exercise training in domestic horses may have resulted in changes in the expression of genes related to metabolism, muscle structure, and the nervous system.

Functional Trade-Offs in Promiscuous Enzymes Cannot Be Explained by Intrinsic Mutational Robustness of the Native Activity.

PubMed

Kaltenbach, Miriam; Emond, Stephane; Hollfelder, Florian; Tokuriki, Nobuhiko

2016-10-01

The extent to which an emerging new function trades off with the original function is a key characteristic of the dynamics of enzyme evolution. Various cases of laboratory evolution have unveiled a characteristic trend; a large increase in a new, promiscuous activity is often accompanied by only a mild reduction of the native, original activity. A model that associates weak trade-offs with "evolvability" was put forward, which proposed that enzymes possess mutational robustness in the native activity and plasticity in promiscuous activities. This would enable the acquisition of a new function without compromising the original one, reducing the benefit of early gene duplication and therefore the selection pressure thereon. Yet, to date, no experimental study has examined this hypothesis directly. Here, we investigate the causes of weak trade-offs by systematically characterizing adaptive mutations that occurred in two cases of evolutionary transitions in enzyme function: (1) from phosphotriesterase to arylesterase, and (2) from atrazine chlorohydrolase to melamine deaminase. Mutational analyses in various genetic backgrounds revealed that, in contrast to the prevailing model, the native activity is less robust to mutations than the promiscuous activity. For example, in phosphotriesterase, the deleterious effect of individual mutations on the native phosphotriesterase activity is much larger than their positive effect on the promiscuous arylesterase activity. Our observations suggest a revision of the established model: weak trade-offs are not caused by an intrinsic robustness of the native activity and plasticity of the promiscuous activity. We propose that upon strong adaptive pressure for the new activity without selection against the original one, selected mutations will lead to the largest possible increases in the new function, but whether and to what extent they decrease the old function is irrelevant, creating a bias towards initially weak trade-offs and the emergence of generalist enzymes.

College Selectivity and Degree Completion

ERIC Educational Resources Information Center

Heil, Scott; Reisel, Liza; Attewell, Paul

2014-01-01

How much of a difference does it make whether a student of a given academic ability enters a more or a less selective four-year college? Some studies claim that attending a more academically selective college markedly improves one's graduation prospects. Others report the reverse: an advantage from attending an institution where one's own skills…

Native Electrospray Ionization Mass Spectrometry Reveals Multiple Facets of Aptamer-Ligand Interactions: From Mechanism to Binding Constants.

PubMed

Gülbakan, Basri; Barylyuk, Konstantin; Schneider, Petra; Pillong, Max; Schneider, Gisbert; Zenobi, Renato

2018-06-20

Aptamers are oligonucleotide receptors obtained through an iterative selection process from random-sequence libraries. Though many aptamers for a broad range of targets with high affinity and selectivity have been generated, a lack of high-resolution structural data and the limitations of currently available biophysical tools greatly impede understanding of the mechanisms of aptamer-ligand interactions. Here we demonstrate that an approach based on native electrospray ionization mass spectrometry (ESI-MS) can be successfully applied to characterize aptamer-ligand complexes in all details. We studied an adenosine-binding aptamer (ABA), a l-argininamide-binding aptamer (LABA), and a cocaine-binding aptamer (CBA) and their noncovalent interactions with ligands by native ESI-MS and complemented these measurements by ion mobility spectrometry (IMS), isothermal titration calorimetry (ITC), and circular dichroism (CD) spectroscopy. The ligand selectivity of the aptamers and the respective complex stoichiometry could be determined by the native ESI-MS approach. The ESI-MS data can also help refining the binding model for aptamer-ligand complexes and deliver accurate aptamer-ligand binding affinities for specific and nonspecific binding events. For specific ligands, we found K d1 = 69.7 μM and K d2 = 5.3 μM for ABA (two binding sites); K d1 = 22.04 μM for LABA; and K d1 = 8.5 μM for CBA.

Predicting risk for medical malpractice claims using quality-of-care characteristics.

PubMed Central

Charles, S C; Gibbons, R D; Frisch, P R; Pyskoty, C E; Hedeker, D; Singha, N K

1992-01-01

The current fault-based tort system assumes that claims made against physicians are inversely related to the quality of care they provide. In this study we identified physician characteristics associated with elements of medical care that make physicians vulnerable to malpractice claims. A sample of physicians (n = 248) thought to be at high or low risk for claims was surveyed on various personal and professional characteristics. Statistical analysis showed that 9 characteristics predicted risk group. High risk was associated with increased age, surgical specialty, emergency department coverage, increased days away from practice, and the feeling that the litigation climate was "unfair." Low risk was associated with scheduling enough time to talk with patients, answering patients' telephone calls directly, feeling "satisfied" with practice arrangements, and acknowledging greater emotional distress. Prediction was more accurate for physicians in practice 15 years or less. We conclude that a relationship exists between a history of malpractice claims and selected physician characteristics. PMID:1462538

[Asbestos exposure in the petrochemical industry and interaction with other occupational risk factors: analysis of the last ten years INAIL data].

PubMed

Innocenzi, Mariano; Saldutti, Elisa; Bindi, Luciano; Di Giacobbe, Andrea; Mercadante, Lucina; Innocenzi, Ludovico

2013-01-01

The present study analyzes the trend of occupational diseases, in particular those asbestos-related, in the petrochemical industry from 2002 to 2011, taking into account the number of diseases claimed to and compensated by the National Institute for Insurance of Workplace Accidents and Occupational Diseases (INAIL), assessing risk factors and possible interactions. To identify the research areas, we selected INAIL cost codes, related to the petrochemical industry. In the last five years, over the total claims submitted by industrial workers, 54% of claims for asbestosis, 76.7% of claims for neoplastic diseases, and 78.6% of claims for pleural plaques have been compensated. In the petrochemical industry, such percentages are respectively 59.2%, 81.6% and 82.7%. These data suggest possible interactions between asbestos and other risk factors, particularly significant in the petrochemical industry, although difficult to identify, as well as an initial underestimation of asbestos exposure in this industry.

Ultra-processed family foods in Australia: nutrition claims, health claims and marketing techniques.

PubMed

Pulker, Claire Elizabeth; Scott, Jane Anne; Pollard, Christina Mary

2018-01-01

To objectively evaluate voluntary nutrition and health claims and marketing techniques present on packaging of high-market-share ultra-processed foods (UPF) in Australia for their potential impact on public health. Cross-sectional. Packaging information from five high-market-share food manufacturers and one retailer were obtained from supermarket and manufacturers' websites. Ingredients lists for 215 UPF were examined for presence of added sugar. Packaging information was categorised using a taxonomy of nutrition and health information which included nutrition and health claims and five common food marketing techniques. Compliance of statements and claims with the Australia New Zealand Food Standards Code and with Health Star Ratings (HSR) were assessed for all products. Almost all UPF (95 %) contained added sugars described in thirty-four different ways; 55 % of UPF displayed a HSR; 56 % had nutrition claims (18 % were compliant with regulations); 25 % had health claims (79 % were compliant); and 97 % employed common food marketing techniques. Packaging of 47 % of UPF was designed to appeal to children. UPF carried a mean of 1·5 health and nutrition claims (range 0-10) and 2·6 marketing techniques (range 0-5), and 45 % had HSR≤3·0/5·0. Most UPF packaging featured nutrition and health statements or claims despite the high prevalence of added sugars and moderate HSR. The degree of inappropriate or inaccurate statements and claims present is concerning, particularly on packaging designed to appeal to children. Public policies to assist parents to select healthy family foods should address the quality and accuracy of information provided on UPF packaging.

Expanding the use of administrative claims databases in conducting clinical real-world evidence studies in multiple sclerosis.

PubMed

Capkun, Gorana; Lahoz, Raquel; Verdun, Elisabetta; Song, Xue; Chen, Weston; Korn, Jonathan R; Dahlke, Frank; Freitas, Rita; Fraeman, Kathy; Simeone, Jason; Johnson, Barbara H; Nordstrom, Beth

2015-05-01

Administrative claims databases provide a wealth of data for assessing the effect of treatments in clinical practice. Our aim was to propose methodology for real-world studies in multiple sclerosis (MS) using these databases. In three large US administrative claims databases: MarketScan, PharMetrics Plus and Department of Defense (DoD), patients with MS were selected using an algorithm identified in the published literature and refined for accuracy. Algorithms for detecting newly diagnosed ('incident') MS cases were also refined and tested. Methodology based on resource and treatment use was developed to differentiate between relapses with and without hospitalization. When various patient selection criteria were applied to the MarketScan database, an algorithm requiring two MS diagnoses at least 30 days apart was identified as the preferred method of selecting patient cohorts. Attempts to detect incident MS cases were confounded by the limited continuous enrollment of patients in these databases. Relapse detection algorithms identified similar proportions of patients in the MarketScan and PharMetrics Plus databases experiencing relapses with (2% in both databases) and without (15-20%) hospitalization in the 1 year follow-up period, providing findings in the range of those in the published literature. Additional validation of the algorithms proposed here would increase their credibility. The methods suggested in this study offer a good foundation for performing real-world research in MS using administrative claims databases, potentially allowing evidence from different studies to be compared and combined more systematically than in current research practice.

Phytoremediation potential and ecological and phenological changes of native pioneer plants from weathered oil spill-impacted sites at tropical wetlands.

PubMed

Palma-Cruz, Felipe de J; Pérez-Vargas, Josefina; Rivera Casado, Noemí Araceli; Gómez Guzmán, Octavio; Calva-Calva, Graciano

2016-08-01

Pioneer native plant species from weathered oil spill-affected sites were selected to study their potential for phytoremediation on the basis of their ecological and phenological changes during the phytoremediation process. Experiments were conducted in field and in greenhouse. In field, native plants from aged oil spill-impacted sites with up 400 g of weathered petroleum hydrocarbons per kilogram soil were selected. In the impacted sites, the principal dominant plant species with potential for hydrocarbons removal were Cyperus laxus, Cyperus esculentus, and Ludwigia peploides. In greenhouse, the phenology of the selected plant species was drastically affected by the hydrocarbons level above 325 g total petroleum hydrocarbons (TPH) per kilogram soil after 2 years of phytoremediation of soils from the aged oil spill-impacted sites. From the phytoremediation treatments, a mix-culture of C. laxus, C. esculentus, and L. peploides in soil containing 325 g TPH/kg soil, from which 20.3 % were polyaromatic hydrocarbons (PAH) and 34.2 % were asphaltenes (ASF), was able to remove up 93 % of the TPH, while in unvegetated soil the TPH removal was 12.6 %. Furthermore, evaluation of the biodiversity and life forms of plant species in the impacted sites showed that phytoremediation with C. esculentus, alone or in a mix-culture with C. laxus and L. peploides, reduces the TPH to such extent that the native plant community was progressively reestablished by replacing the cultivated species resulting in the ecological recovery of the affected soil. These results demonstrate that native Cyperus species from weathered oil spill-affected sites, specifically C. esculentus and C. laxus, alone or in a mix-culture, have particular potential for phytoremediation of soils from tropical wetlands contaminated with weathered oil hydrocarbons.

Population mitogenomics provides insights into evolutionary history, source of invasions and diversifying selection in the House Crow (Corvus splendens).

PubMed

Krzemińska, Urszula; Morales, Hernán E; Greening, Chris; Nyári, Árpád S; Wilson, Robyn; Song, Beng Kah; Austin, Christopher M; Sunnucks, Paul; Pavlova, Alexandra; Rahman, Sadequr

2018-04-01

The House Crow (Corvus splendens) is a useful study system for investigating the genetic basis of adaptations underpinning successful range expansion. The species originates from the Indian subcontinent, but has successfully spread through a variety of thermal environments across Asia, Africa and Europe. Here, population mitogenomics was used to investigate the colonisation history and to test for signals of molecular selection on the mitochondrial genome. We sequenced the mitogenomes of 89 House Crows spanning four native and five invasive populations. A Bayesian dated phylogeny, based on the 13 mitochondrial protein-coding genes, supports a mid-Pleistocene (~630,000 years ago) divergence between the most distant genetic lineages. Phylogeographic patterns suggest that northern South Asia is the likely centre of origin for the species. Codon-based analyses of selection and assessments of changes in amino acid properties provide evidence of positive selection on the ND2 and ND5 genes against a background of purifying selection across the mitogenome. Protein homology modelling suggests that four amino acid substitutions inferred to be under positive selection may modulate coupling efficiency and proton translocation mediated by OXPHOS complex I. The identified substitutions are found within native House Crow lineages and ecological niche modelling predicts suitable climatic areas for the establishment of crow populations within the invasive range. Mitogenomic patterns in the invasive range of the species are more strongly associated with introduction history than climate. We speculate that invasions of the House Crow have been facilitated by standing genetic variation that accumulated due to diversifying selection within the native range.

On the Origin of the Canonical Nucleobases: An Assessment of Selection Pressures across Chemical and Early Biological Evolution

PubMed Central

Rios, Andro C.

2014-01-01

The native bases of RNA and DNA are prominent examples of the narrow selection of organic molecules upon which life is based. How did nature “decide” upon these specific heterocycles? Evidence suggests that many types of heterocycles could have been present on the early Earth. It is therefore likely that the contemporary composition of nucleobases is a result of multiple selection pressures that operated during early chemical and biological evolution. The persistence of the fittest heterocycles in the prebiotic environment towards, for example, hydrolytic and photochemical assaults, may have given some nucleobases a selective advantage for incorporation into the first informational polymers. The prebiotic formation of polymeric nucleic acids employing the native bases remains, however, a challenging problem to reconcile. Hypotheses have proposed that the emerging RNA world may have included many types of nucleobases. This is supported by the extensive utilization of non-canonical nucleobases in extant RNA and the resemblance of many of the modified bases to heterocycles generated in simulated prebiotic chemistry experiments. Selection pressures in the RNA world could have therefore narrowed the composition of the nucleic acid bases. Two such selection pressures may have been related to genetic fidelity and duplex stability. Considering these possible selection criteria, the native bases along with other related heterocycles seem to exhibit a certain level of fitness. We end by discussing the strength of the N-glycosidic bond as a potential fitness parameter in the early DNA world, which may have played a part in the refinement of the alphabetic bases. PMID:25284884

Assisted migration: What it means to nursery managers and tree planters

Treesearch

Mary I. Williams; R. Kasten Dumroese

2014-01-01

Projections indicate that natural plant adaptation and migration may not keep pace with climate changes. This mismatch in rates will pose significant challenges for practitioners that select, grow, and outplant native tree species. Populations of native tree species planted today must be able to meet the climatic challenges they will face during this century. One...

Polysemous Verbs and Modality in Native and Non-Native Argumentative Writing: A Corpus-Based Study

ERIC Educational Resources Information Center

Salazar, Danica; Verdaguer, Isabel

2009-01-01

The present study is a corpus-based analysis of a selection of polysemous lexical verbs used to express modality in student argumentative writing. Twenty-three lexical verbs were searched for in three 100,000-word corpora of argumentative essays written in English by American, Filipino and Spanish university students. Concordance lines were…

78 FR 28241 - Notice of Approval of Record of Decision for Plan To Protect and Restore Native Ecosystems by...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-14

... Non-Native Ungulates, Hawaii Volcanoes National Park, Hawaii AGENCY: National Park Service, Interior...: Hawaii Volcanoes National Park has selected and will implement Alternative D (identified as the agency... Superintendent, Hawaii Volcanoes National Park, P.O. Box 52, Hawaii National Park, HI 96718-0052 or via telephone...

What Shall Our Children Read? A Selected Bibliography of American Indian Literature for Young People.

ERIC Educational Resources Information Center

Blank, Ruth

The 178 titles in the annotated bibliography represent a variety of American Indian and Alaska Native topics and literature from 1953 to 1980 (primarily the 1970's). Serving as a guide for teachers and Native American parents, the bibliography alphabetically lists published material non-stereotypic of American Indians and suitable for teaching…

"Winds of Change" Magazine's 6th Annual College Guide for American Indians.

ERIC Educational Resources Information Center

Sorensen, Barbara, Ed.; Pierce, Dick, Ed.

1999-01-01

This guide provides college information tailored for American Indian and Alaska Native students, their families, and their counselors. The heart of the guide is a unique compilation of 199 schools selected because they have a supportive American Indian community and graduate a good percentage of their Native undergraduates. In a double-page…

Selected Bibliography of Spanish for Native Speaker Sources.

ERIC Educational Resources Information Center

Rodriguez Pino, Cecilia, Comp.

This bibliography was prepared for middle school and high school teachers participating in a conference at New Mexico State University (July 14-18, 1993), to assist in research and pedagogical endeavors in the teaching of Spanish to native speakers. It is presented in two parts. The first is a bibliography edited by Francisco J. Ronquillo, which…

A Novel Semi-biosynthetic Route for Artemisinin Production Using Engineered Substrate-Promiscuous P450BM3

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dietrich, Jeffrey; Yoshikuni, Yasuo; Fisher, Karl

2009-11-30

Production of fine heterologus pathways in microbial hosts is frequently hindered by insufficient knowledge of the native metabolic pathway and its cognate enzymes; often the pathway is unresolved and enzymes lack detailed characterization. An alternative paradigm to using native pathways is de novo pathway design using well-characterized, substrate-promiscuous enzymes. We demonstrate this concept using P450BM3 from Bacillus megaterium. Using a computer model, we illustrate how key P450BM3 activ site mutations enable binding of non-native substrate amorphadiene, incorporating these mutations into P450BM3 enabled the selective oxidation of amorphadiene arteminsinic-11s,12-epoxide, at titers of 250 mg L"1 in E. coli. We also demonstratemore » high-yeilding, selective transformations to dihydroartemisinic acid, the immediate precursor to the high value anti-malarial drug artemisinin.« less

Spread of an introduced parasite across the Hawaiian archipelago independent of its introduced host

DOE PAGES

Gagne, Roderick B.; Hogan, J. Derek; McIntyre, Peter B.; ...

2014-11-11

1. Co-introductions of non-native parasites with non-native hosts can be a major driver of disease emergence in native species, but the conditions that promote the establishment and spread of nonnative parasites remain poorly understood. Here, we characterise the infection of a native host species by a non-native parasite relative to the distribution and density of the original non-native host species and a suite of organismal and environmental factors that have been associated with parasitism, but not commonly considered within a single system. 2. We examined the native Hawaiian goby Awaous stamineus across 23 catchments on five islands for infection bymore » the non-native nematode parasite Camallanus cotti. We used model selection to test whether parasite infection was associated with the genetic diversity, size and population density of native hosts, the distribution and density of non-native hosts, land use and water quality. 3. We found that the distribution of non-native C. cotti parasites has become decoupled from the non-native hosts that were primary vectors of introduction to the Hawaiian Islands. Although no single intrinsic or extrinsic factor was identified that best explains parasitism of A. stamineus by C. cotti, native host size, population density and water quality were consistently identified as influencing parasite intensity and prevalence. 4. The introduction of non-native species can indirectly influence native species through infection of co-introduced parasites. Here, we show that the effects of enemy addition can extend beyond the range of non-native hosts through the independent spread of non-native parasites. This suggests that control of non-native hosts is not sufficient to halt the spread of introduced parasites. Furthermore, designing importation regulations to prevent host parasite co-introductions can promote native species conservation, even in remote areas that may not seem susceptible to human influence.« less

From Extraction of Local Structures of Protein Energy Landscapes to Improved Decoy Selection in Template-Free Protein Structure Prediction.

PubMed

Akhter, Nasrin; Shehu, Amarda

2018-01-19

Due to the essential role that the three-dimensional conformation of a protein plays in regulating interactions with molecular partners, wet and dry laboratories seek biologically-active conformations of a protein to decode its function. Computational approaches are gaining prominence due to the labor and cost demands of wet laboratory investigations. Template-free methods can now compute thousands of conformations known as decoys, but selecting native conformations from the generated decoys remains challenging. Repeatedly, research has shown that the protein energy functions whose minima are sought in the generation of decoys are unreliable indicators of nativeness. The prevalent approach ignores energy altogether and clusters decoys by conformational similarity. Complementary recent efforts design protein-specific scoring functions or train machine learning models on labeled decoys. In this paper, we show that an informative consideration of energy can be carried out under the energy landscape view. Specifically, we leverage local structures known as basins in the energy landscape probed by a template-free method. We propose and compare various strategies of basin-based decoy selection that we demonstrate are superior to clustering-based strategies. The presented results point to further directions of research for improving decoy selection, including the ability to properly consider the multiplicity of native conformations of proteins.

Significant genetic differentiation between native and introduced silver carp (Hypophthalmichthys molitrix) inferred from mtDNA analysis

USGS Publications Warehouse

Li, S.-F.; Xu, J.-W.; Yang, Q.-L.; Wang, C.H.; Chapman, D.C.; Lu, G.

2011-01-01

Silver carp Hypophthalmichthys molitrix (Cyprinidae) is native to China and has been introduced to over 80 countries. The extent of genetic diversity in introduced silver carp and the genetic divergence between introduced and native populations remain largely unknown. In this study, 241 silver carp sampled from three major native rivers and two non-native rivers (Mississippi River and Danube River) were analyzed using nucleotide sequences of mitochondrial COI gene and D-loop region. A total of 73 haplotypes were observed, with no haplotype found common to all the five populations and eight haplotypes shared by two to four populations. As compared with introduced populations, all native populations possess both higher haplotype diversity and higher nucleotide diversity, presumably a result of the founder effect. Significant genetic differentiation was revealed between native and introduced populations as well as among five sampled populations, suggesting strong selection pressures might have occurred in introduced populations. Collectively, this study not only provides baseline information for sustainable use of silver carp in their native country (i.e., China), but also offers first-hand genetic data for the control of silver carp in countries (e.g., the United States) where they are considered invasive.

Comment on "Flexible Asymmetric Supercapacitors Based on Nitrogen-Doped Graphene Hydrogels with Embedded Nickel Hydroxide Nanoplates".

PubMed

Vongehr, Sascha

2017-05-22

It is argued that the main claims of "Flexible Asymmetric Supercapacitors Based on Nitrogen-Doped Graphene Hydrogels with Embedded Nickel Hydroxide Nanoplates" are strongly exaggerated. By selecting first a subregion (ΔV) of the total voltage drop, the capacitance (C ΔV ) is inflated by 30 %. Then, by selecting different regions for different properties and using different ΔV values in different terms of a single expression for the energy density (E ΔV ), the value is doubled. A bending angle of only 45° is instead claimed to be 180°. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Vowel reduction in word-final position by early and late Spanish-English bilinguals.

PubMed

Byers, Emily; Yavas, Mehmet

2017-01-01

Vowel reduction is a prominent feature of American English, as well as other stress-timed languages. As a phonological process, vowel reduction neutralizes multiple vowel quality contrasts in unstressed syllables. For bilinguals whose native language is not characterized by large spectral and durational differences between tonic and atonic vowels, systematically reducing unstressed vowels to the central vowel space can be problematic. Failure to maintain this pattern of stressed-unstressed syllables in American English is one key element that contributes to a "foreign accent" in second language speakers. Reduced vowels, or "schwas," have also been identified as particularly vulnerable to the co-articulatory effects of adjacent consonants. The current study examined the effects of adjacent sounds on the spectral and temporal qualities of schwa in word-final position. Three groups of English-speaking adults were tested: Miami-based monolingual English speakers, early Spanish-English bilinguals, and late Spanish-English bilinguals. Subjects performed a reading task to examine their schwa productions in fluent speech when schwas were preceded by consonants from various points of articulation. Results indicated that monolingual English and late Spanish-English bilingual groups produced targeted vowel qualities for schwa, whereas early Spanish-English bilinguals lacked homogeneity in their vowel productions. This extends prior claims that schwa is targetless for F2 position for native speakers to highly-proficient bilingual speakers. Though spectral qualities lacked homogeneity for early Spanish-English bilinguals, early bilinguals produced schwas with near native-like vowel duration. In contrast, late bilinguals produced schwas with significantly longer durations than English monolinguals or early Spanish-English bilinguals. Our results suggest that the temporal properties of a language are better integrated into second language phonologies than spectral qualities. Finally, we examined the role of nonstructural variables (e.g. linguistic history measures) in predicting native-like vowel duration. These factors included: Age of L2 learning, amount of L1 use, and self-reported bilingual dominance. Our results suggested that different sociolinguistic factors predicted native-like reduced vowel duration than predicted native-like vowel qualities across multiple phonetic environments.

Vowel reduction in word-final position by early and late Spanish-English bilinguals

PubMed Central

2017-01-01

Vowel reduction is a prominent feature of American English, as well as other stress-timed languages. As a phonological process, vowel reduction neutralizes multiple vowel quality contrasts in unstressed syllables. For bilinguals whose native language is not characterized by large spectral and durational differences between tonic and atonic vowels, systematically reducing unstressed vowels to the central vowel space can be problematic. Failure to maintain this pattern of stressed-unstressed syllables in American English is one key element that contributes to a “foreign accent” in second language speakers. Reduced vowels, or “schwas,” have also been identified as particularly vulnerable to the co-articulatory effects of adjacent consonants. The current study examined the effects of adjacent sounds on the spectral and temporal qualities of schwa in word-final position. Three groups of English-speaking adults were tested: Miami-based monolingual English speakers, early Spanish-English bilinguals, and late Spanish-English bilinguals. Subjects performed a reading task to examine their schwa productions in fluent speech when schwas were preceded by consonants from various points of articulation. Results indicated that monolingual English and late Spanish-English bilingual groups produced targeted vowel qualities for schwa, whereas early Spanish-English bilinguals lacked homogeneity in their vowel productions. This extends prior claims that schwa is targetless for F2 position for native speakers to highly-proficient bilingual speakers. Though spectral qualities lacked homogeneity for early Spanish-English bilinguals, early bilinguals produced schwas with near native-like vowel duration. In contrast, late bilinguals produced schwas with significantly longer durations than English monolinguals or early Spanish-English bilinguals. Our results suggest that the temporal properties of a language are better integrated into second language phonologies than spectral qualities. Finally, we examined the role of nonstructural variables (e.g. linguistic history measures) in predicting native-like vowel duration. These factors included: Age of L2 learning, amount of L1 use, and self-reported bilingual dominance. Our results suggested that different sociolinguistic factors predicted native-like reduced vowel duration than predicted native-like vowel qualities across multiple phonetic environments. PMID:28384234

GEOTHERMAL ENVIRONMENTAL ASSESSMENT: BEHAVIOR OF SELECTED GEOTHERMAL BRINE CONTAMINANTS IN PLANTS AND SOILS

EPA Science Inventory

The behavior of selected elements found in the Roosevelt Hot Springs KGRA geothermal fluids was investigated in both plant and soil systems. The kinetics of these potential environmental containments were studied by using soil columns and selected cultivated and native plant spec...

Predatory functional response and prey choice identify predation differences between native/invasive and parasitised/unparasitised crayfish.

PubMed

Haddaway, Neal R; Wilcox, Ruth H; Heptonstall, Rachael E A; Griffiths, Hannah M; Mortimer, Robert J G; Christmas, Martin; Dunn, Alison M

2012-01-01

Invasive predators may change the structure of invaded communities through predation and competition with native species. In Europe, the invasive signal crayfish Pacifastacus leniusculus is excluding the native white clawed crayfish Austropotamobius pallipes. This study compared the predatory functional responses and prey choice of native and invasive crayfish and measured impacts of parasitism on the predatory strength of the native species. Invasive crayfish showed a higher (>10%) prey (Gammarus pulex) intake rate than (size matched) natives, reflecting a shorter (16%) prey handling time. The native crayfish also showed greater selection for crustacean prey over molluscs and bloodworm, whereas the invasive species was a more generalist predator. A. pallipes parasitised by the microsporidian parasite Thelohania contejeani showed a 30% reduction in prey intake. We suggest that this results from parasite-induced muscle damage, and this is supported by a reduced (38%) attack rate and increased (30%) prey handling time. Our results indicate that the per capita (i.e., functional response) difference between the species may contribute to success of the invader and extinction of the native species, as well as decreased biodiversity and biomass in invaded rivers. In addition, the reduced predatory strength of parasitized natives may impair their competitive abilities, facilitating exclusion by the invader.

The effects of native language on Indian English sounds and timing patterns

PubMed Central

Sirsa, Hema; Redford, Melissa A.

2013-01-01

This study explored whether the sound structure of Indian English (IE) varies with the divergent native languages of its speakers or whether it is similar regardless of speakers' native languages. Native Hindi (Indo-Aryan) and Telugu (Dravidian) speakers produced comparable phrases in IE and in their native languages. Naïve and experienced IE listeners were then asked to judge whether different sentences had been spoken by speakers with the same or different native language backgrounds. The findings were an interaction between listener experience and speaker background such that only experienced listeners appropriately distinguished IE sentences produced by speakers with different native language backgrounds. Naïve listeners were nonetheless very good at distinguishing between Hindi and Telugu phrases. Acoustic measurements on monophthongal vowels, select obstruent consonants, and suprasegmental temporal patterns all differentiated between Hindi and Telugu, but only 3 of the measures distinguished between IE produced by speakers of the different native languages. The overall results are largely consistent with the idea that IE has a target phonology that is distinct from the phonology of native Indian languages. The subtle L1 effects on IE may reflect either the incomplete acquisition of the target phonology or, more plausibly, the influence of sociolinguistic factors on the use and evolution of IE. PMID:24860200

The Effect of a Federal Controlled Substance Act Schedule Change on Hydrocodone Combination Products Claims in a Medicaid Population.

PubMed

Tran, Stephanie; Lavitas, Pavel; Stevens, Karen; Greenwood, Bonnie C; Clements, Karen; Alper, Caroline J; Lenz, Kimberly; Price, Mylissa; Hydery, Tasmina; Arnold, Jennifer L; Takeshita, Mito; Bacon, Rachel; Peristere, Justin P; Jeffrey, Paul L

2017-05-01

In 2012, hydrocodone combination products (HCPs) were the most prescribed medications in the United States. Under the Controlled Substance Act of 1970, hydrocodone alone was classified as a Schedule II drug, while HCPs were classified as Schedule III, indicating a lower risk for abuse and misuse. However, according to a Drug Enforcement Agency analysis, the addition of nonopioids has not been shown to diminish abuse potential of hydrocodone. In response to concerns for drug abuse and overdose, the Drug Enforcement Agency rescheduled HCPs to Schedule II in October 2014, with the intent of limiting overprescribing and increasing awareness of their abuse potential. However, it is unknown whether this has affected the overall claims for HCPs in a Medicaid population. To (a) compare the trend in HCP prescription claims with select non-HCP (opioid and nonopioid) analgesic claims before and after the HCP schedule change in the Massachusetts Medicaid fee-for-service/Primary Care Clinician plan population and (b) identify if there was a change in HCP new start member and claim characteristics before and after the HCP schedule change. This quasi-experimental, retrospective study used enrollment and pharmacy claims data to evaluate all members in the study population 1 year before and after the HCP schedule change. The number of claims for HCPs and select non-HCP analgesics was reported as the monthly rate per total population, and an interrupted time series analysis compared the change in the monthly rate of claims across groups. Members with 1 or more pharmacy claims for a new HCP prescription during a 5-month period before or after the HCP schedule change were analyzed to determine member demographics (age, gender, and number of claims) and claim characteristics (average daily dose, average quantity per claim, and days supply). The rate of HCP claims increased before and decreased after the HCP schedule change. Controlling for the trend during the period before the HCP schedule change, the rate of HCP claims per 1,000 members per month decreased at a greater rate than non-HCP analgesics in the period after the HCP schedule change (P < 0.001). The percentage of HCP claims for new start members decreased after the HCP schedule change (44.9% vs. 34.1% of all HCP claims pre- to post-schedule change; P < 0.001). In the group of new starts, there was not a significant difference in the average daily dose (26.3 mg vs. 26.4 mg; P = 0.69), while there was a decrease in average number of tablets dispensed per claim (from 37.1 to 20.3 tablets; P < 0.001) and an increase in the percentage of claims for a shorter days supply (from 57.7% to 81.6%; P < 0.001). The findings of this study suggest that the HCP schedule change may have contributed to the decrease in claims for HCPs in a Medicaid population. After the HCP schedule change, there was a trend towards decreased HCP use among new starts. No outside funding supported this study. The authors have nothing to disclose. Study concept and design were contributed by all authors except for Arnold and Clements. Tran, Arnold, and Clements took the lead in data collection, along with Peristere, and data interpretation was performed by all the authors, except Arnold. The manuscript was written primarily by Tran, along with Lavitas, Stevens, and Greenwood, and revised by all the authors except Arnold and Peristere. A poster of this research project was presented at the Academy of Managed Care Pharmacy's 2016 Annual Meeting in San Francisco, California, April 2016.

Bovine lactoferrin digested with human gastrointestinal enzymes inhibits replication of human echovirus 5 in cell culture.

PubMed

Furlund, Camilla B; Kristoffersen, Anja B; Devold, Tove G; Vegarud, Gerd E; Jonassen, Christine M

2012-07-01

Many infant formulas are enriched with lactoferrin (Lf) because of its claimed beneficial effects on health. Native bovine Lf (bLf) is known to inhibit in vitro replication of human enteroviruses, a group of pathogenic viruses that replicate in the gut as their primary infection site. On the basis of a model digestion and human gastrointestinal enzymes, we hypothesized that bLf could retain its antiviral properties against enterovirus in the gastrointestinal tract, either as an intact protein or through bioactive peptide fragments released by digestive enzymes. To test our hypothesis, bLf was digested with human gastric juice and duodenal juice in a 2-step in vitro digestion model. Two gastric pH levels and reduction conditions were used to simulate physiological conditions in adults and infants. The antiviral activity of native bLf and of the digested fractions was studied on echovirus 5 in vitro, using various assay conditions, addressing several mechanisms for replication inhibition. Both native and digested bLf fractions revealed a significant inhibitory effect, when added before or simultaneously with the virus onto the cells. Furthermore, a significant stronger sustained antiviral effect was observed when bLf was fully digested in the gastric phase with fast pH reduction to 2.5, compared with native bLf, suggesting the release of antiviral peptides from bLf during the human digestion process. In conclusion, this study demonstrates that bLf may have a role in the prevention of human gastrointestinal virus infection under physiological conditions and that food containing bLf may protect against infection in vivo. Copyright © 2012 Elsevier Inc. All rights reserved.

Evaluation of dynamic thiol/disulphide homeostasis as a novel indicator of oxidative stress in maple syrup urine disease patients under treatment.

PubMed

Zubarioglu, Tanyel; Kiykim, Ertugrul; Cansever, Mehmet Serif; Neselioglu, Salim; Aktuglu-Zeybek, Cigdem; Erel, Ozcan

2017-02-01

Maple syrup urine disease (MSUD) is a metabolic disorder that is caused by deficiency of branched-chain α-keto acid dehydrogenase complex. Although accumulation of toxic metabolites is associated with neurotoxicity, mechanisms underlying brain damage remain unclear. Aim of this study is to evaluate thiol/disulphide homeostasis as a novel indicator of oxidative stress in MSUD patients under treatment. Twenty patients with MSUD and 20 healthy individuals were included in study. All patients were under regular follow-up and had a good metabolic control. Serum native thiol (-SH), total thiol (-SH + -S-S-), disulphide (-S-S) levels were measured in all subjects. Disulphide/native thiol, disulphide/total thiol and native thiol/total thiol ratios were calculated from these values. Simultaneous blood sampling for plasma quantitative amino acid analysis was performed in both groups. Any significant difference was not observed in -SH, -SH + -S-S-, -S-S levels between two groups. In addition no increase of disulphide/native thiol and disulphide/total thiol ratios was detected in patient group. This study is the first study that evaluates dynamic thiol/disulphide homeostasis as an indicator of oxidative stress in MSUD patients. Among previous studies that were made to determine oxidative stress in treated MSUD patients, this study had the largest sample size also. In recent studies, it was claimed that oxidative stress could be responsible from neurotoxicity even in treated patients. Here, dynamic thiol/disulfide homeostasis status showed that providing good metabolic control in MSUD patients prevent oxidative stress. Under regular follow-up and good compliance with diet, additional antioxidant therapies would possibly not be necessary.

Constructing abortion as a social problem: "Sex selection" and the British abortion debate.

PubMed

Lee, Ellie

2017-02-01

Between February 2012 and March 2015, the claim that sex selection abortion was taking place in Britain and that action needed to be taken to stop it dominated debate in Britain about abortion. Situating an analysis in sociological and social psychological approaches to the construction of social problems, particularly those considering "feminised" re-framings of anti-abortion arguments, this paper presents an account of this debate. Based on analysis of media coverage, Parliamentary debate and official documents, we focus on claims about grounds (evidence) made to sustain the case that sex selection abortion is a British social problem and highlight how abortion was problematised in new ways. Perhaps most notable, we argue, was the level of largely unchallenged vilification of abortion doctors and providers, on the grounds that they are both law violators and participants in acts of discrimination and violence against women, especially those of Asian heritage. We draw attention to the role of claims made by feminists in the media and in Parliament about "gendercide" as part of this process and argue that those supportive of access to abortion need to critically assess both this aspect of the events and also consider arguments about the problems of "medical power" in the light of what took place.

Chemical analyses of elutriates, native water, and bottom material from the Chetco, Rogue, and Columbia rivers in western Oregon

USGS Publications Warehouse

Fuhrer, Gregory J.

1984-01-01

Chemical analyses of elutriates, bottom sediment, and water samples for selected metals, nutrients and organic compounds including insecticides, herbicides, and acid/neutral extractables have been made to provide data to determine short-term water-quality conditions associated with dredging operations in rivers and estuaries. Between April and August 1982, data were collected from the Chetco and Rogue River estuaries in southwestern Oregon, and from the mouth of the Columbia River in the northwestern Oregon to Cathlamet Bay, 18.2 miles upstream. In an elutriation test, bottom materials from a potential dredge site are mixed with native water - collected from either a dredge or disposal site - and the liquid portion of the mixture is removed, filtered, and chemically analyzed. Presented in this report are chemical and physical analyses of elutriates, native water, and bottom material for selected metals, ammonia, organic carbon, pesticides, particle size, and gas chromatographic/mass spectrometric semi-quantitative organic scans. Elutriate and bottom-material samples were screened specifically for phenolic compounds, particularly the chlorinated phenols; phenol was the only compound identified. Elutriate-test results showed variability for selected trace-metal concentrations of dissolved chemicals as follows: in micrograms per liter, arsenic ranged from < 1 to 15, cadmium from 1 to 210, copper from < 1 to 13, chromium from < 1 to 5, and nickel from 2 to 18. Results of computations to determine the amount of a constituent associated with bottom material and interstitial water and subsequently released (dissolved) into the elutriate-test native-mixing water are presented for selected trace metals. The highest elutriate-test release was 35 percent for manganese; the second highest, 5 percent for cadmium. All other computed releases were less than or equal to 1 percent. (USGS)

Reproductive habitat selection in alien and native populations of the genus Discoglossus

NASA Astrophysics Data System (ADS)

Escoriza, Daniel; Boix, Dani

2014-08-01

The existence of suitable breeding habitats is an important factor explaining the regional presence of an anuran species. This study examined patterns of habitat selection in populations of three species of the genus Discoglossus: Discoglossusgalganoi (south-western Iberian Peninsula), Discoglossusscovazzi (Morocco) and Discoglossuspictus (three different areas were included in the study: Sicily, Tunisia and north-eastern Iberian Peninsula). The populations of D. pictus on the Iberian Peninsula are allochthonous, and analysis of these patterns may provide insights into the processes that regulate the invasion phase. The hypotheses tested were: (i) congeneric species show the same patterns of habitat selection, and alien species have been established following these patterns; (ii) there are differences in species associations between assemblages structured deterministically and by chance, i.e. native versus invaded assemblages. The larval habitats of three species of this genus were characterized by measuring physical and chemical parameters of the water bodies. We examined the covariation between the presence of Discoglossus species and the species richness of sympatric anurans, and investigated a possible relationship between morphological similarity (as a proxy of functional group) and overlap in habitat use. The results showed that congeneric species are morphologically conservative and also select very similar types of aquatic habitat. The alien population and other sympatric species showed a high degree of overlap in habitat use, which was greater than that observed in the native assemblage with a similar functional richness. Species associations were not structured on the basis of morphological similarity in any of the assemblages. Among native populations, the presence of Discoglossus was either negatively correlated or not significantly correlated with species richness. Only the alien population showed a positive correlation between its presence and species richness, which suggests a loss of assemblage structure.

A Syntactic Account for the Power of Verbs within X-Phemism: A Corpus-Base Exploration

ERIC Educational Resources Information Center

Al-Rawi, Maather Mohammad; Al-Shurafa, Nuha Suleiman Daoud

2016-01-01

The main aim of this paper is to examine the syntactic status of a selected text-corpus focus, with a special focus on the verb within its Verb-Phrase. The major claim is that the power of the verb in its VP is loaded syntactically through which the speaker's desire of the doublespeak within X-Phemism is achieved. In order to fulfill this claim, a…

State of the science and challenges of breeding landscape plants with ecological function

PubMed Central

Wilde, H Dayton; Gandhi, Kamal J K; Colson, Gregory

2015-01-01

Exotic plants dominate esthetically-managed landscapes, which cover 30–40 million hectares in the United States alone. Recent ecological studies have found that landscaping with exotic plant species can reduce biodiversity on multiple trophic levels. To support biodiversity in urbanized areas, the increased use of native landscaping plants has been advocated by conservation groups and US federal and state agencies. A major challenge to scaling up the use of native species in landscaping is providing ornamental plants that are both ecologically functional and economically viable. Depending on ecological and economic constraints, accelerated breeding approaches could be applied to ornamental trait development in native plants. This review examines the impact of landscaping choices on biodiversity, the current status of breeding and selection of native ornamental plants, and the interdisciplinary research needed to scale up landscaping plants that can support native biodiversity. PMID:26504560

Cooperative Tertiary Interaction Network Guides RNA Folding

DOE Office of Scientific and Technical Information (OSTI.GOV)

Behrouzi, Reza; Roh, Joon Ho; Kilburn, Duncan

2013-04-08

Noncoding RNAs form unique 3D structures, which perform many regulatory functions. To understand how RNAs fold uniquely despite a small number of tertiary interaction motifs, we mutated the major tertiary interactions in a group I ribozyme by single-base substitutions. The resulting perturbations to the folding energy landscape were measured using SAXS, ribozyme activity, hydroxyl radical footprinting, and native PAGE. Double- and triple-mutant cycles show that most tertiary interactions have a small effect on the stability of the native state. Instead, the formation of core and peripheral structural motifs is cooperatively linked in near-native folding intermediates, and this cooperativity depends onmore » the native helix orientation. The emergence of a cooperative interaction network at an early stage of folding suppresses nonnative structures and guides the search for the native state. We suggest that cooperativity in noncoding RNAs arose from natural selection of architectures conducive to forming a unique, stable fold.« less

Status of native stream fishes within selected protected areas of Niobrara River in western Nebraska

USGS Publications Warehouse

Spurgeon, Jonathan J.; Stasiak, Richard H.; Cunningham, George R.; Pope, Kevin L.; Pegg, Mark A.

2014-01-01

Lotic systems within the Great Plains are characterized by highly fluctuating conditions through both space and time. Fishes inhabiting these systems have adopted specific life-history strategies to survive in such environments; however, anthropogenic disturbance to prairie streams has resulted in declines and extirpation of many native stream fishes. Terrestrial protected areas (i.e., parks and reserves) are designated to support native flora and fauna and, it is assumed, to provide protection to native fishes. We assessed the presence and relative abundance of stream fish populations within protected areas along the Niobrara River in western Nebraska based on data collected during 1979, 1989, 2008, and 2011. The spatial extent of protection, landscape changes resulting in degraded physiochemical parameters, and introduced species may reduce the effectiveness of these terrestrial protected areas in protecting native fishes in Great Plains stream environments.

Wet thermal accumulation modeling of germination of western U.S. rangeland species

Treesearch

Jennifer K. Rawlins

2009-01-01

The key to stopping high-frequency or catastrophic wildfires in the western U.S. is the successful restoration of burned lands to native plant communities. Developing models of establishment for invasive and native species will help in the selection of species for restoration projects that are able to establish and compete with invasive species given the abiotic...

Native plant development and restoration program for the Great Basin, USA

Treesearch

N. L. Shaw; M. Pellant; P. Olweli; S. L. Jensen; E. D. McArthur

2008-01-01

The Great Basin Native Plant Selection and Increase Project, organized by the USDA Bureau of Land Management, Great Basin Restoration Initiative and the USDA Forest Service, Rocky Mountain Research Station in 2000 as a multi-agency collaborative program (http://www.fs.fed.us/rm/boise/research/shrub/greatbasin.shtml), has the objective of improving the availability of...

Orchard Display Nursery evaluation summary (2005-2006)

Treesearch

Derek J. Tilley; Loren St. John

2006-01-01

The Orchard Display Nursery was planted on November 16, 2004 in cooperation with the Great Basin Native Plant Selection and Increase Project. The nursery includes 82 accessions of 27 native and introduced grass, forb and shrub species. Each accession was planted in 7 X 60 foot plots. See Tilley et al (2005) for descriptions of the species and accessions planted. The...

Release of native and amended boron from arid zone soils after varying incubation times

USDA-ARS?s Scientific Manuscript database

In this study we evaluated the boron (B) release from soils containing elevated native B and examined the extent to which incubation time affected B release. Five soils varying in initial pH and clay content were selected for the study. The soils were spiked with five varying doses of B as H3BO3 (...

The extent of selected non-native invasive plants on Missouri forestland

Treesearch

W. Keith Moser; Mark H. Hansen; Mark D. Nelson

2008-01-01

The Northern Research Station's Forest Inventory and Analysis Program (NRSFIA) collects forest-related data throughout a 24-state region in the northeastern United States, ranging from North Dakota to Maine and Kansas to Maryland. Based on discussions with stakeholders and others, NRS-FIA found that the impact of non-native invasive plants (NNIPs) may be known at...

Establishment of native species on a natural gas pipeline: the importance of seeding rate, aspect, and species selection

Treesearch

Melissa A. Thomas-Van Gundy; Pamela J. Edwards; Thomas M. Schuler

2018-01-01

With the increase in natural gas production in the United States, land managers need solutions and best practices to mitigate potential negative impacts of forest and soil disturbance and meet landowner objectives and desired conditions. Mitigation often includes the use of native seed mixes for maintaining plant diversity, controlling nonnative invasive species, and...

Small mammal communities and habitat selection in Northern Rocky Mountain bunchgrass: Implications for exotic plant invasions

Treesearch

Dean E. Pearson; Yvette K. Ortega; Kevin S. McKelvey; Leonard F. Ruggiero

2001-01-01

Agriculture and development have dramatically reduced the range of native bunchgrass habitats in the Northern Rocky Mountains, and the invasion of exotic plants threatens to greatly alter the remaining pristine prairie. Small mammals play many important roles in ecosystem functions, but little is known about small mammal community composition and structure in native...

5.0 Monitoring methods for forests vulnerable to non-native invasive pest species

Treesearch

David W. Williams; Michael E. Montgomery; Kathleen S. Shields; Richard A. Evans

2008-01-01

Non-native invasive species pose a serious threat to forest resources, requiring programs to monitor their spatial spread and the damage they inflict on forest ecosystems. Invasive species research in the Delaware River Basin (DRB) had three primary objectives: to develop and evaluate monitoring protocols for selected pests and resulting ecosystem damage at the IMRAs...

Persian Native Speakers Reading Persian and English Texts: Their Strategic Behavior to Overcome Syntactic and Semantic Problems

ERIC Educational Resources Information Center

Alimorad, Zahra

2015-01-01

This study aimed to discover semantic and syntactic problems Persian native speakers might have while reading English and Persian texts and different strategies they use to overcome those problems. To this end, a convenient sample of 40 intermediate students studying English Literature at Shiraz University was selected. Twenty of them were asked…

Use of Health Care Claims Data to Study Patients with Ophthalmologic Conditions

PubMed Central

Stein, Joshua D.; Lum, Flora; Lee, Paul P.; Rich, William L.; Coleman, Anne L.

2014-01-01

Objective To describe what information is or is not included in health care claims data, provide an overview of the main advantages and limitations of performing analyses using health care claims data, and offer general guidance on how to report and interpret findings of ophthalmology-related claims data analyses. Design Systematic review. Participants Not applicable. Methods A literature review and synthesis of methods for claims-based data analyses. Main Outcome Measures Not applicable. Results Some advantages of using claims data for analyses include large, diverse sample sizes, longitudinal follow-up, lack of selection bias, and potential for complex, multivariable modeling. The disadvantages include (a) the inherent limitations of claims data, such as incomplete, inaccurate, or missing data, or the lack of specific billing codes for some conditions; and (b) the inability, in some circumstances, to adequately evaluate the appropriateness of care. In general, reports of claims data analyses should include clear descriptions of the following methodological elements: the data source, the inclusion and exclusion criteria, the specific billing codes used, and the potential confounding factors incorporated in the multivariable models. Conclusions The use of claims data for research is expected to increase with the enhanced availability of data from Medicare and other sources. The use of claims data to evaluate resource use and efficiency and to determine the basis for supplementary payment methods for physicians is anticipated. Thus, it will be increasingly important for eye care providers to use accurate and descriptive codes for billing. Adherence to general guidance on the reporting of claims data analyses, as outlined in this article, is important to enhance the credibility and applicability of findings. Guidance on optimal ways to conduct and report ophthalmology-related investigations using claims data will likely continue to evolve as health services researchers refine the metrics to analyze large administrative data sets. PMID:24433971

Content analysis of false and misleading claims in television advertising for prescription and nonprescription drugs.

PubMed

Faerber, Adrienne E; Kreling, David H

2014-01-01

False and misleading advertising for drugs can harm consumers and the healthcare system, and previous research has demonstrated that physician-targeted drug advertisements may be misleading. However, there is a dearth of research comparing consumer-targeted drug advertising to evidence to evaluate whether misleading or false information is being presented in these ads. To compare claims in consumer-targeted television drug advertising to evidence, in order to evaluate the frequency of false or misleading television drug advertising targeted to consumers. A content analysis of a cross-section of television advertisements for prescription and nonprescription drugs aired from 2008 through 2010. We analyzed commercial segments containing prescription and nonprescription drug advertisements randomly selected from the Vanderbilt Television News Archive, a census of national news broadcasts. For each advertisement, the most-emphasized claim in each ad was identified based on claim iteration, mode of communication, duration and placement. This claim was then compared to evidence by trained coders, and categorized as being objectively true, potentially misleading, or false. Potentially misleading claims omitted important information, exaggerated information, made lifestyle associations, or expressed opinions. False claims were factually false or unsubstantiated. Of the most emphasized claims in prescription (n = 84) and nonprescription (n = 84) drug advertisements, 33 % were objectively true, 57 % were potentially misleading and 10 % were false. In prescription drug ads, there were more objectively true claims (43 %) and fewer false claims (2 %) than in nonprescription drug ads (23 % objectively true, 7 % false). There were similar numbers of potentially misleading claims in prescription (55 %) and nonprescription (61 %) drug ads. Potentially misleading claims are prevalent throughout consumer-targeted prescription and nonprescription drug advertising on television. These results are in conflict with proponents who argue the social value of drug advertising is found in informing consumers about drugs.

Selection of Native Tree Species for Subtropical Forest Restoration in Southwest China.

PubMed

Lu, Yang; Ranjitkar, Sailesh; Harrison, Rhett D; Xu, Jianchu; Ou, Xiaokun; Ma, Xuelan; He, Jun

2017-01-01

The use of native species in forest restoration has been increasingly recognized as an effective means of restoring ecosystem functions and biodiversity to degraded areas across the world. However, successful selection of species adapted to local conditions requires specific knowledge which is often lacking, especially in developing countries. In order to scale up forest restoration, experimental data on the responses of native species to propagation and restoration treatments across a range of local conditions are required. In this study, the restoration potential of 34 native tree species was evaluated based on nursery research and field planting experiments at a highly degraded site in a subtropical area of southwest China. We examined species performance in terms of germination rates as well as survival rates and growth over 2 years after planting. Of the 34 species examined, 25 had a germination percentage greater than 50%. Survivorship ranged from 0 to 97% across species and was greater than 50% for 20 species. Mean monthly growth increments varied between species. Pioneer species performed well, and 14 mid- and late-successional species performed reasonably well to very well in this study. However, the remaining 16 mid- and late-successional species performed poorly. These results indicate that carefully selected mid- and late-successional species can be effectively incorporated into mixed species plantings. This data can be used to inform restoration planning, helping to identify suitable species and so enhance the biodiversity and resilience of restored forests.

Selection of Native Tree Species for Subtropical Forest Restoration in Southwest China

PubMed Central

Lu, Yang; Ranjitkar, Sailesh; Harrison, Rhett D.; Xu, Jianchu; Ou, Xiaokun; Ma, Xuelan; He, Jun

2017-01-01

The use of native species in forest restoration has been increasingly recognized as an effective means of restoring ecosystem functions and biodiversity to degraded areas across the world. However, successful selection of species adapted to local conditions requires specific knowledge which is often lacking, especially in developing countries. In order to scale up forest restoration, experimental data on the responses of native species to propagation and restoration treatments across a range of local conditions are required. In this study, the restoration potential of 34 native tree species was evaluated based on nursery research and field planting experiments at a highly degraded site in a subtropical area of southwest China. We examined species performance in terms of germination rates as well as survival rates and growth over 2 years after planting. Of the 34 species examined, 25 had a germination percentage greater than 50%. Survivorship ranged from 0 to 97% across species and was greater than 50% for 20 species. Mean monthly growth increments varied between species. Pioneer species performed well, and 14 mid- and late-successional species performed reasonably well to very well in this study. However, the remaining 16 mid- and late-successional species performed poorly. These results indicate that carefully selected mid- and late-successional species can be effectively incorporated into mixed species plantings. This data can be used to inform restoration planning, helping to identify suitable species and so enhance the biodiversity and resilience of restored forests. PMID:28103281

EFL/ESL Textbook Selection in Korea and East Asia - Relevant Issues and Literature Review

NASA Astrophysics Data System (ADS)

Meurant, Robert C.

EFL/ESL departments periodically face the problem of textbook selection. Cogent issues are that non-native speakers will use L2 English mainly to communicate with other non-native English speakers, so an American accent is becoming less important. L2 English will mainly be used in computer-mediated communication, hence the importance of L2 Digital Literacy. The convergence of Information Communication Technologies is radically impacting Second Language Acquisition, which is integrating web-hosted Assessment and Learning Management Systems. EFL/ESL textbooks need to be compatible with blended learning, prepare students for a globalized world, and foster autonomous learning. I summarize five papers on EFL/ESL textbook evaluation and selection, and include relevant material for adaptation. Textbooks are major sources of contact with the target language, so selection is an important decision. Educators need to be systematic and objective in their approach, adopting a selection process that is open, transparent, accountable, participatory, informed and rigorous.

A Selective Mutism Arising from First Language Attrition, Successfully Treated with Paroxetine-CBT Combination Treatment.

PubMed

Serra, Agostino; Di Mauro, Paola; Andaloro, Claudio; Maiolino, Luigi; Pavone, Piero; Cocuzza, Salvatore

2015-10-01

After immersion in a foreign language, speakers often have difficulty retrieving native-language words and may experience a decrease in its proficiency, this phenomenon, in the non-pathological form, is known as first language attrition. Self-perception of this low native-language proficiency and apprehension occurring when speaking is expected and, may sometimes lead these people to a state of social anxiety and, in extreme forms, can involve the withholding of speech as a primitive tool for self-protection, linking them to selective mutism. We report an unusual case of selective mutism arising from first language attrition in an Italian girl after attending a two-year "German language school", who successfully responded to a paroxetine-cognitive behavioral treatment (CBT) combination treatment.

A Selective Mutism Arising from First Language Attrition, Successfully Treated with Paroxetine-CBT Combination Treatment

PubMed Central

Serra, Agostino; Di Mauro, Paola; Andaloro, Claudio; Maiolino, Luigi; Pavone, Piero

2015-01-01

After immersion in a foreign language, speakers often have difficulty retrieving native-language words and may experience a decrease in its proficiency, this phenomenon, in the non-pathological form, is known as first language attrition. Self-perception of this low native-language proficiency and apprehension occurring when speaking is expected and, may sometimes lead these people to a state of social anxiety and, in extreme forms, can involve the withholding of speech as a primitive tool for self-protection, linking them to selective mutism. We report an unusual case of selective mutism arising from first language attrition in an Italian girl after attending a two-year "German language school", who successfully responded to a paroxetine-cognitive behavioral treatment (CBT) combination treatment. PMID:26508972

Claimed effects, outcome variables and methods of measurement for health claims proposed under European Community Regulation 1924/2006 in the area of blood glucose and insulin concentrations.

PubMed

Martini, Daniela; Biasini, Beatrice; Zavaroni, Ivana; Bedogni, Giorgio; Musci, Marilena; Pruneti, Carlo; Passeri, Giovanni; Ventura, Marco; Galli, Daniela; Mirandola, Prisco; Vitale, Marco; Dei Cas, Alessandra; Bonadonna, Riccardo C; Del Rio, Daniele

2018-04-01

Most requests for authorization to bear health claims under Articles 13(5) and 14 related to blood glucose and insulin concentration/regulation presented to the European Food Safety Authority (EFSA) receive a negative opinion. Reasons for such decisions are mainly ascribable to poor substantiation of the claimed effects. In this scenario, a project was carried out aiming at critically analysing the outcome variables (OVs) and methods of measurement (MMs) to be used to substantiate health claims, with the final purpose to improve the quality of applications provided by stakeholders to EFSA. This manuscript provides a position statement of the experts involved in the project, reporting the results of an investigation aimed to collect, collate and critically analyse the information relevant to claimed effects (CEs), OVs and MMs related to blood glucose and insulin levels and homoeostasis compliant with Regulation 1924/2006. The critical analysis of OVs and MMs was performed with the aid of the pertinent scientific literature and was aimed at defining their appropriateness (alone or in combination with others) to support a specific CE. The results can be used to properly select OVs and MMs in a randomized controlled trial, for an effective substantiation of the claims, using the reference method(s) whenever available. Moreover, results can help EFSA in updating the guidance for the scientific requirements of health claims.

Algorithms to identify colonic ischemia, complications of constipation and irritable bowel syndrome in medical claims data: development and validation.

PubMed

Sands, Bruce E; Duh, Mei-Sheng; Cali, Clorinda; Ajene, Anuli; Bohn, Rhonda L; Miller, David; Cole, J Alexander; Cook, Suzanne F; Walker, Alexander M

2006-01-01

A challenge in the use of insurance claims databases for epidemiologic research is accurate identification and verification of medical conditions. This report describes the development and validation of claims-based algorithms to identify colonic ischemia, hospitalized complications of constipation, and irritable bowel syndrome (IBS). From the research claims databases of a large healthcare company, we selected at random 120 potential cases of IBS and 59 potential cases each of colonic ischemia and hospitalized complications of constipation. We sought the written medical records and were able to abstract 107, 57, and 51 records, respectively. We established a 'true' case status for each subject by applying standard clinical criteria to the available chart data. Comparing the insurance claims histories to the assigned case status, we iteratively developed, tested, and refined claims-based algorithms that would capture the diagnoses obtained from the medical records. We set goals of high specificity for colonic ischemia and hospitalized complications of constipation, and high sensitivity for IBS. The resulting algorithms substantially improved on the accuracy achievable from a naïve acceptance of the diagnostic codes attached to insurance claims. The specificities for colonic ischemia and serious complications of constipation were 87.2 and 92.7%, respectively, and the sensitivity for IBS was 98.9%. U.S. commercial insurance claims data appear to be usable for the study of colonic ischemia, IBS, and serious complications of constipation. (c) 2005 John Wiley & Sons, Ltd.

Indigenous traditional knowledge and substance abuse treatment outcomes: the problem of efficacy evaluation.

PubMed

Gone, Joseph P

2012-09-01

In the field of substance abuse treatment, American Indian and Alaska Native (AI/AN) communities have routinely incorporated ceremonial practices as one important component in the promotion of recovery and healing. The beneficial effects of such practices are frequently described as plainly apparent by community-based advocates, providers, and professionals alike. In the present era of evidence-based substance abuse intervention, however, indigenous integration of such practices raises questions pertaining to the systematic evaluation of treatment efficacy. The focus of this article is outcome evaluation. Although intervention outcome researchers recognize the randomized controlled trial as the "gold standard" against which claims of treatment efficacy are measured, AI/AN efficacy assertions grounded in indigenous traditional knowledge (ITK) reflect different concerns that have emerged in non-Western historical contexts. The interface between scientific and indigenous "ways of knowing" is explored here relative to efficacy claims about substance abuse treatment. Distinguishing features of both scientific knowing and ITK are summarized and compared. ITK has been described as personal and experiential, reflecting the primacy of autonomous individual knowing. In contrast, intervention scientists are skeptical of personal inference as a basis for efficacy evaluation. The evident divergence between these epistemic paradigms can result in potentially contradictory claims. Proper appraisal of the status and relevance of ITK for determining treatment efficacy requires further exploration of these marginalized approaches to knowledge. Intervention scientists who work in AI/AN communities should remain open to the legitimacy and role of ITKs in investigations of substance abuse treatment.

Nutrition labelling: purpose, scientific issues and challenges.

PubMed

Van den Wijngaart, Annoek W E M

2002-01-01

Nutrition labels describe the nutrient content of a food and are intended to guide the consumer in food selection. The nutrition information provided must be selected on the basis of consistency with dietary recommendations. Selection of the specific nutrients or food components to be listed should further take into account label space, the analytical feasibility of measuring the particular nutritional component within the food matrix, and the relative costs of such analyses. Nutrition information provided on labels should be truthful and not mislead consumers. At the same time, labelling regulations should provide incentives to manufacturers to develop products that promote public health and assist consumers in following dietary recommendations. It is likely that in many countries, there would be some segments of the population that would benefit from information about the composition of foods. In these cases, countries should consider the need to provide for appropriate labelling and its presentation relative to existing guidelines and approaches. As nutrition-labelling efforts have evolved, different approaches and legal requirements have been established. These create difficulties in developing and harmonizing nutrition information listings, which have broad international applications. For these reasons, the Codex Guidelines on Nutrition Labeling play an important role to provide guidance to member countries when they want to develop or update their national regulations and to encourage harmonization of national standards with international standards. These Guidelines are based on the principle that no food should be described or presented in a manner that is false, misleading or deceptive. The Guidelines include provisions for voluntary nutrient declaration, calculation and presentation of nutrient information. The Guidelines on Claims establish general principles to be followed and leave the definition of specific claims to national regulations. Definitions are provided for a number of claims (nutrient content, comparative claims, nutrient function claims) as well as general requirements concerning consumer information in relation with claims. Nutrition labelling by itself cannot solve nutrition problems. It should be seen as one of the elements of nutrition policy and should be envisaged in the larger perspective of consumer education, which in its turn is part of an overall development policy. Exchange of information at the regional and subregional level is important, as each country can learn from the experience of others and regional co-ordination and co-operation can be developed.

Non-native megaherbivores: the case for novel function to manage plant invasions on islands

PubMed Central

Hansen, Dennis M.

2015-01-01

There is a heated debate about whether all non-native species are ‘guilty until proven innocent’, or whether some should be accepted or even welcomed. Further fanning the flames, I here present a case where introductions of carefully vetted, non-native species could provide a net conservation benefit. On many islands, native megaherbivores (flightless birds, tortoises) recently went extinct. Here, rewilding with carefully selected non-native species as ecological replacements is increasingly considered a solution, reinstating a herbivory regime that largely benefits the native flora. Based on these efforts, I suggest that restoration practitioners working on islands without a history of native megaherbivores that are threatened by invasive plants should consider introducing a non-native island megaherbivore, and that large and giant tortoises are ideal candidates. Such tortoises would be equally useful on islands where eradication of invasive mammals has led to increased problems with invasive plants, or on islands that never had introduced mammalian herbivores, but where invasive plants are a problem. My proposal may seem radical, but the reversibility of using giant tortoises means that nothing is lost from trying, and that indeed much is to be gained. As an easily regulated adaptive management tool, it represents an innovative, hypothesis-driven ‘innocent until proven guilty’ approach. PMID:26194166

Selecting Capabilities for Quality of Life Measurement

ERIC Educational Resources Information Center

Robeyns, Ingrid

2005-01-01

The capability approach advocates that interpersonal comparisons be made in the space of functionings and capabilities. However, Amartya Sen has not specified which capabilities should be selected as the relevant ones. This has provoked two types of criticism. The stronger critique is Martha Nussbaum's claim that Sen should endorse one specific…

Telling Tales at Work: An Evolutionary Explanation

ERIC Educational Resources Information Center

Yang, Chulguen

2013-01-01

This article explores the adaptive functions of storytelling in the workplace from an evolutionary perspective. Based on the analysis of ethnographic studies on hunter-gatherer and modern work organizations, this article claims that storytelling, as an adapted cognitive device, was selectively retained by natural and sexual selection, because of…

Project Selection in the Design Studio: Absence of Learning Environments

ERIC Educational Resources Information Center

Basa, Inci

2010-01-01

Project selection is an essential matter of design teaching. Based on observations of a specific curriculum, the author claims that a wide repertoire of subjects including offices, restaurants, hotels, and other public places are used to prepare design students, but that schools and other "learning environments/ schools" are similarly…

Invasive alien plants benefit more from clonal integration in heterogeneous environments than natives.

PubMed

Wang, Yong-Jian; Müller-Schärer, Heinz; van Kleunen, Mark; Cai, Ai-Ming; Zhang, Ping; Yan, Rong; Dong, Bi-Cheng; Yu, Fei-Hai

2017-12-01

What confers invasive alien plants a competitive advantage over native plants remains open to debate. Many of the world's worst invasive alien plants are clonal and able to share resources within clones (clonal integration), particularly in heterogeneous environments. Here, we tested the hypothesis that clonal integration benefits invasive clonal plants more than natives and thus confers invasives a competitive advantage. We selected five congeneric and naturally co-occurring pairs of invasive alien and native clonal plants in China, and grew pairs of connected and disconnected ramets under heterogeneous light, soil nutrient and water conditions that are commonly encountered by alien plants during their invasion into new areas. Clonal integration increased biomass of all plants in all three heterogeneous resource environments. However, invasive plants benefited more from clonal integration than natives. Consequently, invasive plants produced more biomass than natives. Our results indicate that clonal integration may confer invasive alien clonal plants a competitive advantage over natives. Therefore, differences in the ability of clonal integration could potentially explain, at least partly, the invasion success of alien clonal plants in areas where resources are heterogeneously distributed. © 2017 The Authors. New Phytologist © 2017 New Phytologist Trust.

Activity of disaccharidases in arctic populations: evolutionary aspects disaccharidases in arctic populations.

PubMed

Kozlov, Andrew; Vershubsky, Galina; Borinskaya, Svetlana; Sokolova, Maria; Nuvano, Vladislav

2005-07-01

Disorders of dietary sugar assimilation occur more often among native people of the Arctic then in temperate climate inhabitants. It is hypothesized that the limited variety of natural exogenous sugars in the Arctic, and their low content in the traditional diets of native northerners in accordance with a "protein-lipid" type of metabolism weakened selection, favoring diversity of disaccharidase enzymes.

Amazonian forest restoration: an innovative system for native species selection based on phenological data and performance indices

Treesearch

Oliver H. Knowles; John A. Parrotta

1995-01-01

One hundred and sixty taxa of upland moist forest trees were studied with reference to their suitability for forest restoration on bauxite mined Iands in western Para State, Brazil. Over a 14-year period, field observations in native primary forests, nursery studies, and evaluations of over 600 ha of mixed-species reforestation areas were used to characterize fruiting...

A strategy for maximizing native plant material diversity for ecological restoration, germplasm conservation and genecology research

Treesearch

Berta Youtie; Nancy Shaw; Matt Fisk; Scott Jensen

2012-01-01

One of the most important steps in planning a restoration project is careful selection of ecologically adapted native plant material. As species-specific seed zone maps are not available for most species in the Artemisia tridentata ssp. wyomingensis (Wyoming big sagebrush) ecoregion in the Great Basin, USA, we are employing a provisional seed zone map based on annual...

Issues in the Education of American Indian and Alaska Native Students with Disabilities. ERIC Digest.

ERIC Educational Resources Information Center

Faircloth, Susan; Tippeconnic, John W., III

Over 10 percent of American Indian and Alaska Native (AI/AN) students in public schools and more than 18 percent of AI/AN students in Bureau of Indian Affairs and tribal schools are eligible for or placed in special education programs. This digest addresses four selected issues in the education of AI/AN students with disabilities. First, the 1997…

Improving predicted protein loop structure ranking using a Pareto-optimality consensus method.

PubMed

Li, Yaohang; Rata, Ionel; Chiu, See-wing; Jakobsson, Eric

2010-07-20

Accurate protein loop structure models are important to understand functions of many proteins. Identifying the native or near-native models by distinguishing them from the misfolded ones is a critical step in protein loop structure prediction. We have developed a Pareto Optimal Consensus (POC) method, which is a consensus model ranking approach to integrate multiple knowledge- or physics-based scoring functions. The procedure of identifying the models of best quality in a model set includes: 1) identifying the models at the Pareto optimal front with respect to a set of scoring functions, and 2) ranking them based on the fuzzy dominance relationship to the rest of the models. We apply the POC method to a large number of decoy sets for loops of 4- to 12-residue in length using a functional space composed of several carefully-selected scoring functions: Rosetta, DOPE, DDFIRE, OPLS-AA, and a triplet backbone dihedral potential developed in our lab. Our computational results show that the sets of Pareto-optimal decoys, which are typically composed of approximately 20% or less of the overall decoys in a set, have a good coverage of the best or near-best decoys in more than 99% of the loop targets. Compared to the individual scoring function yielding best selection accuracy in the decoy sets, the POC method yields 23%, 37%, and 64% less false positives in distinguishing the native conformation, indentifying a near-native model (RMSD < 0.5A from the native) as top-ranked, and selecting at least one near-native model in the top-5-ranked models, respectively. Similar effectiveness of the POC method is also found in the decoy sets from membrane protein loops. Furthermore, the POC method outperforms the other popularly-used consensus strategies in model ranking, such as rank-by-number, rank-by-rank, rank-by-vote, and regression-based methods. By integrating multiple knowledge- and physics-based scoring functions based on Pareto optimality and fuzzy dominance, the POC method is effective in distinguishing the best loop models from the other ones within a loop model set.

Improving predicted protein loop structure ranking using a Pareto-optimality consensus method

PubMed Central

2010-01-01

Background Accurate protein loop structure models are important to understand functions of many proteins. Identifying the native or near-native models by distinguishing them from the misfolded ones is a critical step in protein loop structure prediction. Results We have developed a Pareto Optimal Consensus (POC) method, which is a consensus model ranking approach to integrate multiple knowledge- or physics-based scoring functions. The procedure of identifying the models of best quality in a model set includes: 1) identifying the models at the Pareto optimal front with respect to a set of scoring functions, and 2) ranking them based on the fuzzy dominance relationship to the rest of the models. We apply the POC method to a large number of decoy sets for loops of 4- to 12-residue in length using a functional space composed of several carefully-selected scoring functions: Rosetta, DOPE, DDFIRE, OPLS-AA, and a triplet backbone dihedral potential developed in our lab. Our computational results show that the sets of Pareto-optimal decoys, which are typically composed of ~20% or less of the overall decoys in a set, have a good coverage of the best or near-best decoys in more than 99% of the loop targets. Compared to the individual scoring function yielding best selection accuracy in the decoy sets, the POC method yields 23%, 37%, and 64% less false positives in distinguishing the native conformation, indentifying a near-native model (RMSD < 0.5A from the native) as top-ranked, and selecting at least one near-native model in the top-5-ranked models, respectively. Similar effectiveness of the POC method is also found in the decoy sets from membrane protein loops. Furthermore, the POC method outperforms the other popularly-used consensus strategies in model ranking, such as rank-by-number, rank-by-rank, rank-by-vote, and regression-based methods. Conclusions By integrating multiple knowledge- and physics-based scoring functions based on Pareto optimality and fuzzy dominance, the POC method is effective in distinguishing the best loop models from the other ones within a loop model set. PMID:20642859

Experimental studies of adaptation in Clarkia xantiana. III. Phenotypic selection across a subspecies border.

PubMed

Anderson, Jill T; Eckhart, Vincent M; Geber, Monica A

2015-09-01

Sister taxa with distinct phenotypes often occupy contrasting environments in parapatric ranges, yet we generally do not know whether trait divergence reflects spatially varying selection. We conducted a reciprocal transplant experiment to test whether selection favors "native phenotypes" in two subspecies of Clarkia xantiana (Onagraceae), an annual plant in California. For four quantitative traits that differ between subspecies, we estimated phenotypic selection in subspecies' exclusive ranges and their contact zone in two consecutive years. We predicted that in the arid, pollinator-scarce eastern region, selection favors phenotypes of the native subspecies parviflora: small leaves, slow leaf growth, early flowering, and diminutive flowers. In the wetter, pollinator-rich, western range of subspecies xantiana, we expected selection for opposite phenotypes. We investigated pollinator contributions to selection by comparing naturally pollinated and pollen-supplemented individuals. For reproductive traits and for subspecies xantiana, selection generally matched expectations. The contact zone sometimes showed distinctive selection, and in ssp. parviflora selection sometimes favored nonnative phenotypes. Pollinators influenced selection on flowering time but not on flower size. Little temporal variation in selection occurred, possibly because of plastic trait responses across years. Though there were exceptions and some causes of selection remain obscure, phenotypic differentiation between subspecies appears to reflect spatially variable selection. © 2015 The Author(s). Evolution © 2015 The Society for the Study of Evolution.

Quality of claims, references and the presentation of risk results in medical journal advertising: a comparative study in Australia, Malaysia and the United States.

PubMed

Othman, Noordin; Vitry, Agnes I; Roughead, Elizabeth E

2010-05-29

Journal advertising is used by pharmaceutical companies to disseminate medicine information to doctors. The quality of claims, references and the presentation of risk results in Australia and the US has been questioned in several studies. No recent evidence is available on the quality of claims, references and the presentation of risk results in journal advertising in Australia and the US and no Malaysian data have been published. The aim of this study was to compare the quality of claims, references and the presentation of risk results in journal advertising in these three countries. A consecutive sample of 85 unique advertisements from each country was selected from journal advertising published between January 2004 to December 2006. Claims, references and the presentation of risk results in medical journal advertising were compared between the three countries. Less than one-third of the claims were unambiguous claims (Australia, 30%, Malaysia 17%, US, 23%). In Malaysia significantly less unambiguous claims were provided than in Australia and the US (P < 0.001). However, the unambiguous claims were supported by more references than other claims (80%). Most evidence was obtained from at least one randomized controlled trial, a systematic review or meta-analysis (Australia, 84%, Malaysia, 81%, US, 76%) with journal articles being the most commonly cited references in all countries. Data on file were significantly more likely to be cited in the US (17%) than in Australia (2%) and Malaysia (4%) (P < 0.001). Advertisements that provided quantitative information reported risk results exclusively as a relative risk reduction. The majority of claims were vague suggesting poor quality of claims in journal advertising in these three countries. Evidence from a randomized controlled trial, systematic review or meta- analysis was commonly cited to support claims. However, the more frequent use of data that have not been published and independently reviewed in the US compared to Australia and Malaysia raises questions on the quality of references in the US. The use of relative rather than absolute benefits may overemphasize the benefit of medicines which may leave doctors susceptible to misinterpreting information.

Quality of claims, references and the presentation of risk results in medical journal advertising: a comparative study in Australia, Malaysia and the United States

PubMed Central

2010-01-01

Background Journal advertising is used by pharmaceutical companies to disseminate medicine information to doctors. The quality of claims, references and the presentation of risk results in Australia and the US has been questioned in several studies. No recent evidence is available on the quality of claims, references and the presentation of risk results in journal advertising in Australia and the US and no Malaysian data have been published. The aim of this study was to compare the quality of claims, references and the presentation of risk results in journal advertising in these three countries. Methods A consecutive sample of 85 unique advertisements from each country was selected from journal advertising published between January 2004 to December 2006. Claims, references and the presentation of risk results in medical journal advertising were compared between the three countries. Results Less than one-third of the claims were unambiguous claims (Australia, 30%, Malaysia 17%, US, 23%). In Malaysia significantly less unambiguous claims were provided than in Australia and the US (P < 0.001). However, the unambiguous claims were supported by more references than other claims (80%). Most evidence was obtained from at least one randomized controlled trial, a systematic review or meta-analysis (Australia, 84%, Malaysia, 81%, US, 76%) with journal articles being the most commonly cited references in all countries. Data on file were significantly more likely to be cited in the US (17%) than in Australia (2%) and Malaysia (4%) (P < 0.001). Advertisements that provided quantitative information reported risk results exclusively as a relative risk reduction Conclusions The majority of claims were vague suggesting poor quality of claims in journal advertising in these three countries. Evidence from a randomized controlled trial, systematic review or meta- analysis was commonly cited to support claims. However, the more frequent use of data that have not been published and independently reviewed in the US compared to Australia and Malaysia raises questions on the quality of references in the US. The use of relative rather than absolute benefits may overemphasize the benefit of medicines which may leave doctors susceptible to misinterpreting information. PMID:20509953

Model-Selection Theory: The Need for a More Nuanced Picture of Use-Novelty and Double-Counting

PubMed Central

Steele, Katie; Werndl, Charlotte

2018-01-01

Abstract This article argues that common intuitions regarding (a) the specialness of ‘use-novel’ data for confirmation and (b) that this specialness implies the ‘no-double-counting rule’, which says that data used in ‘constructing’ (calibrating) a model cannot also play a role in confirming the model’s predictions, are too crude. The intuitions in question are pertinent in all the sciences, but we appeal to a climate science case study to illustrate what is at stake. Our strategy is to analyse the intuitive claims in light of prominent accounts of confirmation of model predictions. We show that on the Bayesian account of confirmation, and also on the standard classical hypothesis-testing account, claims (a) and (b) are not generally true; but for some select cases, it is possible to distinguish data used for calibration from use-novel data, where only the latter confirm. The more specialized classical model-selection methods, on the other hand, uphold a nuanced version of claim (a), but this comes apart from (b), which must be rejected in favour of a more refined account of the relationship between calibration and confirmation. Thus, depending on the framework of confirmation, either the scope or the simplicity of the intuitive position must be revised. 1 Introduction2 A Climate Case Study3 The Bayesian Method vis-à-vis Intuitions4 Classical Tests vis-à-vis Intuitions5 Classical Model-Selection Methods vis-à-vis Intuitions  5.1 Introducing classical model-selection methods  5.2 Two cases6 Re-examining Our Case Study7 Conclusion PMID:29780170

Model-Selection Theory: The Need for a More Nuanced Picture of Use-Novelty and Double-Counting.

PubMed

Steele, Katie; Werndl, Charlotte

2018-06-01

This article argues that common intuitions regarding (a) the specialness of 'use-novel' data for confirmation and (b) that this specialness implies the 'no-double-counting rule', which says that data used in 'constructing' (calibrating) a model cannot also play a role in confirming the model's predictions, are too crude. The intuitions in question are pertinent in all the sciences, but we appeal to a climate science case study to illustrate what is at stake. Our strategy is to analyse the intuitive claims in light of prominent accounts of confirmation of model predictions. We show that on the Bayesian account of confirmation, and also on the standard classical hypothesis-testing account, claims (a) and (b) are not generally true; but for some select cases, it is possible to distinguish data used for calibration from use-novel data, where only the latter confirm. The more specialized classical model-selection methods, on the other hand, uphold a nuanced version of claim (a), but this comes apart from (b), which must be rejected in favour of a more refined account of the relationship between calibration and confirmation. Thus, depending on the framework of confirmation, either the scope or the simplicity of the intuitive position must be revised. 1   Introduction 2   A Climate Case Study 3   The Bayesian Method vis-à-vis Intuitions 4   Classical Tests vis-à-vis Intuitions 5   Classical Model-Selection Methods vis-à-vis Intuitions    5.1   Introducing classical model-selection methods    5.2   Two cases 6   Re-examining Our Case Study 7   Conclusion .

ERP evidence for different strategies in the processing of case markers in native speakers and non-native learners

PubMed Central

Mueller, Jutta L; Hirotani, Masako; Friederici, Angela D

2007-01-01

Background The present experiments were designed to test how the linguistic feature of case is processed in Japanese by native and non-native listeners. We used a miniature version of Japanese as a model to compare sentence comprehension mechanisms in native speakers and non-native learners who had received training until they had mastered the system. In the first experiment we auditorily presented native Japanese speakers with sentences containing incorrect double nominatives and incorrect double accusatives, and with correct sentences. In the second experiment we tested trained non-natives with the same material. Based on previous research in German we expected an N400-P600 biphasic ERP response with specific modulations depending on the violated case and whether the listeners were native or non-native. Results For native Japanese participants the general ERP response to the case violations was an N400-P600 pattern. Double accusatives led to an additional enhancement of the P600 amplitude. For the learners a native-like P600 was present for double accusatives and for double nominatives. The additional negativity, however, was present in learners only for double nominative violations, and it was characterized by a different topographical distribution. Conclusion The results indicate that native listeners use case markers for thematic as well as syntactic structure building during incremental sentence interpretation. The modulation of the P600 component for double accusatives possibly reflects case specific syntactic restrictions in Japanese. For adult language learners later processes, as reflected in the P600, seem to be more native-like compared to earlier processes. The anterior distribution of the negativity and its selective emergence for canonical sentences were taken to suggest that the non-native learners resorted to a rather formal processing strategy whereby they relied to a large degree on the phonologically salient nominative case marker. PMID:17331265

Genetic analysis of ancestry, admixture and selection in Bolivian and Totonac populations of the New World.

PubMed

Watkins, W Scott; Xing, Jinchuan; Huff, Chad; Witherspoon, David J; Zhang, Yuhua; Perego, Ugo A; Woodward, Scott R; Jorde, Lynn B

2012-05-20

Populations of the Americas were founded by early migrants from Asia, and some have experienced recent genetic admixture. To better characterize the native and non-native ancestry components in populations from the Americas, we analyzed 815,377 autosomal SNPs, mitochondrial hypervariable segments I and II, and 36 Y-chromosome STRs from 24 Mesoamerican Totonacs and 23 South American Bolivians. We analyzed common genomic regions from native Bolivian and Totonac populations to identify 324 highly predictive Native American ancestry informative markers (AIMs). As few as 40-50 of these AIMs perform nearly as well as large panels of random genome-wide SNPs for predicting and estimating Native American ancestry and admixture levels. These AIMs have greater New World vs. Old World specificity than previous AIMs sets. We identify highly-divergent New World SNPs that coincide with high-frequency haplotypes found at similar frequencies in all populations examined, including the HGDP Pima, Maya, Colombian, Karitiana, and Surui American populations. Some of these regions are potential candidates for positive selection. European admixture in the Bolivian sample is approximately 12%, though individual estimates range from 0-48%. We estimate that the admixture occurred ~360-384 years ago. Little evidence of European or African admixture was found in Totonac individuals. Bolivians with pre-Columbian mtDNA and Y-chromosome haplogroups had 5-30% autosomal European ancestry, demonstrating the limitations of Y-chromosome and mtDNA haplogroups and the need for autosomal ancestry informative markers for assessing ancestry in admixed populations.

No evidence for increased performance of a specialist psyllid on invasive French broom

NASA Astrophysics Data System (ADS)

Herrera, Angelica M.; Carruthers, Raymond I.; Mills, Nicholas J.

2011-03-01

Some invasive plants perform better in their area of introduction than in their native region. This may be a consequence of rapid evolutionary change due to different selection pressures encountered in introduced regions. The Evolution of Increased Competitive Ability hypothesis (EICA) suggests that release from natural enemies results in selection of more vigorous plant genotypes as a result of plants allocating resources away from costly herbivore-resistance traits and toward increased growth. We tested the prediction that introduced plant genotypes of Genista monspessulana (Fabaceae) are less resistant to herbivory by a specialist psyllid, Arytinnis hakani (Hemiptera: Psyllidae) by measuring and comparing A. hakani performance on plants from native (southern France) and introduced (California, U.S.) populations. A. hakani performed equally well on plants from the native and introduced regions; there were no significant differences in psyllid egg and nymphal development, nymphal survival rates, female longevity or fecundity between the test plants. Egg survival rates were significantly higher on native populations, but the difference was minimal. These results provide preliminary evidence that native and introduced G. monspessulana populations are equally resistant to A. hakani and do not support the EICA hypothesis prediction of reduced investment in defense in introduced plant populations. Possible explanations for the lack of effects found in this study include the type of parameters measured and the feeding ecology of the herbivore used to test EICA, and finally, that evolutionary changes in plant defense in introduced G. monspessulana populations may not have occurred.

Stress-gradient hypothesis explains susceptibility to Bromus tectorum invasion and community stability in North America's semi-arid Artemisia tridentata wyomingensis ecosystems

USGS Publications Warehouse

Reisner, Michael D.; Doescher, Paul S.; Pyke, David A.

2015-01-01

Results/Conclusions: Cattle herbivory, a novel disturbance and selective force, was a significant component of two overlapping stress gradients most strongly associated with observed shifts in interactions. Facilitation and competition were strongest and most frequent at the highest and lowest stress levels along both gradients, respectively. Contrasting ecological optima among native and non-native beneficiaries led to strikingly different patterns of interactions. The four native bunchgrasses with the strongest competitive response abilities exhibited the strongest facilitation at their upper limits of stress tolerance, while the two non-natives exhibited the strongest competition at the highest stress levels, which coincided with their maximum abundance. Artemisia facilitation enhanced stability at intermediate stress levels by providing a refuge for native bunchgrasses, which in turn reduced the magnitude of B. tectorum invasion. However, facilitation was a destabilizing force at the highest stress levels when native bunchgrasses became obligate beneficiaries dependent on facilitation for their persistence. B. tectorum dominated these communities, and the next fire may convert them to annual grasslands.

TOUCHSTONE II: a new approach to ab initio protein structure prediction.

PubMed

Zhang, Yang; Kolinski, Andrzej; Skolnick, Jeffrey

2003-08-01

We have developed a new combined approach for ab initio protein structure prediction. The protein conformation is described as a lattice chain connecting C(alpha) atoms, with attached C(beta) atoms and side-chain centers of mass. The model force field includes various short-range and long-range knowledge-based potentials derived from a statistical analysis of the regularities of protein structures. The combination of these energy terms is optimized through the maximization of correlation for 30 x 60,000 decoys between the root mean square deviation (RMSD) to native and energies, as well as the energy gap between native and the decoy ensemble. To accelerate the conformational search, a newly developed parallel hyperbolic sampling algorithm with a composite movement set is used in the Monte Carlo simulation processes. We exploit this strategy to successfully fold 41/100 small proteins (36 approximately 120 residues) with predicted structures having a RMSD from native below 6.5 A in the top five cluster centroids. To fold larger-size proteins as well as to improve the folding yield of small proteins, we incorporate into the basic force field side-chain contact predictions from our threading program PROSPECTOR where homologous proteins were excluded from the data base. With these threading-based restraints, the program can fold 83/125 test proteins (36 approximately 174 residues) with structures having a RMSD to native below 6.5 A in the top five cluster centroids. This shows the significant improvement of folding by using predicted tertiary restraints, especially when the accuracy of side-chain contact prediction is >20%. For native fold selection, we introduce quantities dependent on the cluster density and the combination of energy and free energy, which show a higher discriminative power to select the native structure than the previously used cluster energy or cluster size, and which can be used in native structure identification in blind simulations. These procedures are readily automated and are being implemented on a genomic scale.

Non-native earthworms promote plant invasion by ingesting seeds and modifying soil properties

NASA Astrophysics Data System (ADS)

Clause, Julia; Forey, Estelle; Lortie, Christopher J.; Lambert, Adam M.; Barot, Sébastien

2015-04-01

Earthworms can have strong direct effects on plant communities through consumption and digestion of seeds, however it is unclear how earthworms may influence the relative abundance and composition of plant communities invaded by non-native species. In this study, earthworms, seed banks, and the standing vegetation were sampled in a grassland of central California. Our objectives were i) to examine whether the abundances of non-native, invasive earthworm species and non-native grassland plant species are correlated, and ii) to test whether seed ingestion by these worms alters the soil seed bank by evaluating the composition of seeds in casts relative to uningested soil. Sampling locations were selected based on historical land-use practices, including presence or absence of tilling, and revegetation by seed using Phalaris aquatica. Only non-native earthworm species were found, dominated by the invasive European species Aporrectodea trapezoides. Earthworm abundance was significantly higher in the grassland blocks dominated by non-native plant species, and these sites had higher carbon and moisture contents. Earthworm abundance was also positively related to increased emergence of non-native seedlings, but had no effect on that of native seedlings. Plant species richness and total seedling emergence were higher in casts than in uningested soils. This study suggests that there is a potential effect of non-native earthworms in promoting non-native and likely invasive plant species within grasslands, due to seed-plant-earthworm interactions via soil modification or to seed ingestion by earthworms and subsequent cast effects on grassland dynamics. This study supports a growing body of literature for earthworms as ecosystem engineers but highlights the relative importance of considering non-native-native interactions with the associated plant community.

Native fat globules of different sizes selected from raw milk: thermal and structural behavior.

PubMed

Michalski, Marie-Caroline; Ollivon, Michel; Briard, Valérie; Leconte, Nadine; Lopez, Christelle

2004-12-01

The aim of this study was to characterize differences in the thermal and structural behavior between different sized native milk fat globules. A novel microfiltration process permits the selection of native small fat globules (SFG, 1-3 microm) and large fat globules (LFG, >5 microm) in raw milk, that were analyzed by X-ray diffraction (XRD) coupled to differential scanning calorimetry (DSC). There were no major differences in triglyceride crystalline structures between SFG and LFG, after eliminating thermal history and the influence of cooling rates. The three main 3L and 2L crystalline structures appearing under slow cooling existed regardless of globule size. The supercooling increased for the SFG, mainly due to heterogeneous nucleation in winter milk, and also to compositional variations in spring milk. Differences appeared regarding stabilized crystalline forms at 20 degrees C and subsequent cooling: the SFG contained less 2L triglyceride structures than the LFG. These results can be important in dairy manufactures using tempering periods.

Selective attention to a talker's mouth in infancy: role of audiovisual temporal synchrony and linguistic experience.

PubMed

Hillairet de Boisferon, Anne; Tift, Amy H; Minar, Nicholas J; Lewkowicz, David J

2017-05-01

Previous studies have found that infants shift their attention from the eyes to the mouth of a talker when they enter the canonical babbling phase after 6 months of age. Here, we investigated whether this increased attentional focus on the mouth is mediated by audio-visual synchrony and linguistic experience. To do so, we tracked eye gaze in 4-, 6-, 8-, 10-, and 12-month-old infants while they were exposed either to desynchronized native or desynchronized non-native audiovisual fluent speech. Results indicated that, regardless of language, desynchronization disrupted the usual pattern of relative attention to the eyes and mouth found in response to synchronized speech at 10 months but not at any other age. These findings show that audio-visual synchrony mediates selective attention to a talker's mouth just prior to the emergence of initial language expertise and that it declines in importance once infants become native-language experts. © 2016 John Wiley & Sons Ltd.

Risky Business: Do Native Rodents Use Habitat and Odor Cues to Manage Predation Risk in Australian Deserts?

PubMed Central

Spencer, Emma E.; Crowther, Mathew S.; Dickman, Christopher R.

2014-01-01

In open, arid environments with limited shelter there may be strong selection on small prey species to develop behaviors that facilitate predator avoidance. Here, we predicted that rodents should avoid predator odor and open habitats to reduce their probability of encounter with potential predators, and tested our predictions using a native Australian desert rodent, the spinifex hopping-mouse (Notomys alexis). We tested the foraging and movement responses of N. alexis to non-native predator (fox and cat) odor, in sheltered and open macro- and microhabitats. Rodents did not respond to predator odor, perhaps reflecting the inconsistent selection pressure that is imposed on prey species in the desert environment due to the transience of predator-presence. However, they foraged primarily in the open and moved preferentially across open sand. The results suggest that N. alexis relies on escape rather than avoidance behavior when managing predation risk, with its bipedal movement probably allowing it to exploit open environments most effectively. PMID:24587396

Risky business: do native rodents use habitat and odor cues to manage predation risk in Australian deserts?

PubMed

Spencer, Emma E; Crowther, Mathew S; Dickman, Christopher R

2014-01-01

In open, arid environments with limited shelter there may be strong selection on small prey species to develop behaviors that facilitate predator avoidance. Here, we predicted that rodents should avoid predator odor and open habitats to reduce their probability of encounter with potential predators, and tested our predictions using a native Australian desert rodent, the spinifex hopping-mouse (Notomys alexis). We tested the foraging and movement responses of N. alexis to non-native predator (fox and cat) odor, in sheltered and open macro- and microhabitats. Rodents did not respond to predator odor, perhaps reflecting the inconsistent selection pressure that is imposed on prey species in the desert environment due to the transience of predator-presence. However, they foraged primarily in the open and moved preferentially across open sand. The results suggest that N. alexis relies on escape rather than avoidance behavior when managing predation risk, with its bipedal movement probably allowing it to exploit open environments most effectively.

John Adams's Montesquieuean Moment: Enlightened Historicism in the Discourses on Davila.

PubMed

Green, Jonathan

2016-01-01

At the outset of the French Revolution John Adams penned a series of Discourses of Davila, philosophical ruminations on the sixteenth-century French Wars of Religion. Recent historians have read these Discourses in terms of Adams's Machiavellianism-his conviction that men's passions lead to violence, if unrestrained. But this reading overlooks the extent to which Adams intended his Discourses as a particular investigation into the French nation's character, and into whether the revolutionaries could lay claim to a native, French tradition of mixed constitutional government. Situating the Discourses vis-à-vis Adams's contemporaneous reading of Montesquieu, this article argues for an underappreciated historicist dimension to his thought.

2016 Writing Contest Undergraduate Winner: The Relationship Between Medication Adherence and Total Healthcare Expenditures by Race/Ethnicity in Patients with Diabetes in Hawai'i.

PubMed

Sutton, Cori X; Carpenter, Dee-Ann; Sumida, Wesley; Taira, Deborah

2017-07-01

Diabetes is a costly, chronic disease that is becoming increasingly prevalent worldwide. Studies show that Native Hawaiians suffer from higher rates of diabetes and lower rates of medication adherence compared to Caucasians and Japanese. This study compared total annual healthcare expenditures of patients with diabetes in Hawai'i by race and ethnicity and determined whether any existing differences persisted after controlling for medication adherence and demographic factors. The study population consisted of 30,445 individuals, using administrative claims data from a large health plan in Hawai'i. Filipinos, Native Hawaiians, and Other Pacific Islanders had significantly lower medication adherence rates compared to other groups. These ethnic groups also had the lowest median healthcare costs. In contrast, Caucasians had one of the highest medication adherence rates coupled with the highest median annual healthcare expenditures at $5,132. Generalized linear regression models showed that after controlling for demographic factors and medication adherence, Japanese (RR=0.86, 95%CI [0.78, 0.94]), Chinese (RR=0.83, 95%CI [0.73, 0.95]), Filipinos (RR=0.74, 95%CI [0.67, 0.82]), and Native Hawaiians (RR=0.74, 95%CI [0.67, 0.82]) had significantly lower total healthcare costs compared to Caucasians. Costs for Other Pacific Islanders were not significantly different from those of Caucasians. This study provides evidence that total health-related cost is associated with a multitude of factors that further research may reveal.

Risk Adjustment, Reinsurance Improved Financial Outcomes For Individual Market Insurers With The Highest Claims.

PubMed

Jacobs, Paul D; Cohen, Michael L; Keenan, Patricia

2017-04-01

The Affordable Care Act (ACA) reformed the individual health insurance market. Because insurers can no longer vary their offers of coverage based on applicants' health status, the ACA established a risk adjustment program to equalize health-related cost differences across plans. The ACA also established a temporary reinsurance program to subsidize high-cost claims. To assess the impact of these programs, we compared revenues to claims costs for insurers in the individual market during the first two years of ACA implementation (2014 and 2015), before and after the inclusion of risk adjustment and reinsurance payments. Before these payments were included, for the 30 percent of insurers with the highest claims costs, claims (not including administrative expenses) exceeded premium revenues by $90-$397 per enrollee per month. The effect was reversed after these payments were included, with revenues exceeding claims costs by $0-$49 per month. The risk adjustment and reinsurance programs were relatively well targeted in the first two years. While there is ongoing discussion regarding the future of the ACA, our findings can shed light on how risk-sharing programs can address risk selection among insurers-a pervasive issue in all health insurance markets. Project HOPE—The People-to-People Health Foundation, Inc.

Experimental studies of adaptation in Clarkia xantiana. II. Fitness variation across a subspecies border.

PubMed

Geber, Monica A; Eckhart, Vincent M

2005-03-01

Because the range boundary is the locale beyond which a taxon fails to persist, it provides a unique opportunity for studying the limits on adaptive evolution. Adaptive constraints on range expansion are perplexing in view of widespread ecotypic differentiation by habitat and region within a species' range (regional adaptation) and rapid evolutionary response to novel environments. In this study of two parapatric subspecies, Clarkia xantiana ssp. xantiana and C. x. ssp. parviflora, we compared the fitness of population transplants within their native region, in a non-native region within the native range, and in the non-native range to assess whether range expansion might be limited by a greater intensity of selection on colonists of a new range versus a new region within the range. The combined range of the two subspecies spans a west-to-east gradient of declining precipitation in the Sierra Nevada of California, with ssp. xantiana in the west being replaced by ssp. parviflora in the east. Both subspecies had significantly higher fitness in the native range (range adaptation), whereas regional adaptation was weak and was found only in the predominantly outcrossing ssp. xantiana but was absent in the inbreeding ssp. parvifilora. Because selection intensity on transplants was much stronger in the non-native range relative to non-native regions, there is a larger adaptive barrier to range versus regional expansion. Three of five sequential fitness components accounted for regional and range adaptation, but only one of them, survivorship from germination to flowering, contributed to both. Flower number contributed to regional adaptation in ssp. xantiana and fruit set (number of fruits per flower) to range adaptation. Differential survivorship of the two taxa or regional populations of ssp. xantiana in non-native environments was attributable, in part, to biotic interactions, including competition, herbivory, and pollination. For example, low fruit set in ssp. xantiana in the east was likely due to the absence of its principal specialist bee pollinators in ssp. parviflora's range. Thus, convergence on self-fertilization may be necessary for ssp. xantiana to invade ssp. parviflora's range, but the evolution of outcrossing would not be required for ssp. parviflora to invade ssp. xantiana's range.

What kinds of conservatives does social psychology lack, and why?

PubMed

Ross, Lee

2015-01-01

Although Duarte et al.'s claims about the potential benefits of greater political diversity in the ranks of social psychology are apt, their discussion of the decline in such diversity, the role played by self-selection, and the specific domains they cite in discussing an anti-conservative bias raise issues that merit closer examination. The claim that sound research and analysis challenging liberal orthodoxies fails to receive a fair hearing in our journals and professional discourse is also disputed.

Evaluation of marketing claims, ingredients, and nutrient profiles of over-the-counter diets marketed for skin and coat health of dogs.

PubMed

Johnson, Lily N; Heinze, Cailin R; Linder, Deborah E; Freeman, Lisa M

2015-06-15

To evaluate marketing claims, ingredients, and nutrient profiles of over-the-counter diets marketed for skin and coat health of dogs. Cross-sectional study. 24 over-the-counter dry and canned diets marketed for skin and coat health of dogs. Data on marketing claims and ingredients were collected from diet packaging and manufacturer websites. Concentrations of selected nutrients were obtained by contacting the manufacturers and were compared against minimum values for Association of American Feed Control Officials Dog Food Nutrient Profiles for adult dog maintenance based on calorie content. Most diets incorporated marketing terms such as digestive health, sensitive, or premium that are poorly defined and may have limited relevance to skin, coat, or general health. The types and numbers of major ingredients (ie, potential to contribute protein to the diet) differed. The total number of unique major ingredients in each diet ranged from 3 to 8 (median, 5.5), but the total number of unique ingredients in each diet ranged from 28 to 68 (median, 38). Concentrations of nutrients associated with skin and coat condition also differed widely. Results indicated that the large variation among over-the-counter diets marketed for skin and coat health may cause confusion for owners during diet selection. Owners of a dog with dermatologic problems should consult their veterinarian to select a good-quality diet that meets specific nutrient goals.

Probiotic properties of native Lactobacillus spp. strains for dairy calves.

PubMed

Fernández, S; Fraga, M; Silveyra, E; Trombert, A N; Rabaza, A; Pla, M; Zunino, P

2018-04-10

The use of native microorganisms with probiotic capacity is an alternative tool for the treatment and prevention of several diseases that affect animals, such as neonatal calf diarrhoea. The selection of probiotic strains within a collection is based on different in vitro and in vivo assays, which predict their potential. The aim of this study was to characterise a group of native Lactobacillus spp. strains isolated from faeces of healthy calves using an in vitro approach and to assess their ability to colonise the gastrointestinal tract (GIT) of calves. Native Lactobacillus spp. strains were evaluated on their capacity to survive low pH conditions and bile salts presence, biofilm formation and adhesion to both mucus and Caco-2 cells. Based on the in vitro characterisation, four strains (Lactobacillus johnsonii TP1.1, Lactobacillus reuteri TP1.3B, L. johnsonii TP1.6 and Lactobacillus amylovorus TP8.7) were selected to evaluate their capacity to colonise and persist in the GIT of calves. The assessment of enteric persistence involved an in vivo assay with oral administration of probiotics and quantification in faeces of the administered bacterial species with real-time quantitative PCR (qPCR). The study was conducted using 15 calves (1-month-old) which were divided into five groups of three animals, four of which were treated with four different selected strains and one was the control group. Strains TP1.3B and TP1.6 managed to persist in treated animals until ten days after the end of the administration period, indicating that they could be promising candidates for the design of probiotics for calves.

Defining an essence of structure determining residue contacts in proteins.

PubMed

Sathyapriya, R; Duarte, Jose M; Stehr, Henning; Filippis, Ioannis; Lappe, Michael

2009-12-01

The network of native non-covalent residue contacts determines the three-dimensional structure of a protein. However, not all contacts are of equal structural significance, and little knowledge exists about a minimal, yet sufficient, subset required to define the global features of a protein. Characterisation of this "structural essence" has remained elusive so far: no algorithmic strategy has been devised to-date that could outperform a random selection in terms of 3D reconstruction accuracy (measured as the Ca RMSD). It is not only of theoretical interest (i.e., for design of advanced statistical potentials) to identify the number and nature of essential native contacts-such a subset of spatial constraints is very useful in a number of novel experimental methods (like EPR) which rely heavily on constraint-based protein modelling. To derive accurate three-dimensional models from distance constraints, we implemented a reconstruction pipeline using distance geometry. We selected a test-set of 12 protein structures from the four major SCOP fold classes and performed our reconstruction analysis. As a reference set, series of random subsets (ranging from 10% to 90% of native contacts) are generated for each protein, and the reconstruction accuracy is computed for each subset. We have developed a rational strategy, termed "cone-peeling" that combines sequence features and network descriptors to select minimal subsets that outperform the reference sets. We present, for the first time, a rational strategy to derive a structural essence of residue contacts and provide an estimate of the size of this minimal subset. Our algorithm computes sparse subsets capable of determining the tertiary structure at approximately 4.8 A Ca RMSD with as little as 8% of the native contacts (Ca-Ca and Cb-Cb). At the same time, a randomly chosen subset of native contacts needs about twice as many contacts to reach the same level of accuracy. This "structural essence" opens new avenues in the fields of structure prediction, empirical potentials and docking.

Defining an Essence of Structure Determining Residue Contacts in Proteins

PubMed Central

Sathyapriya, R.; Duarte, Jose M.; Stehr, Henning; Filippis, Ioannis; Lappe, Michael

2009-01-01

The network of native non-covalent residue contacts determines the three-dimensional structure of a protein. However, not all contacts are of equal structural significance, and little knowledge exists about a minimal, yet sufficient, subset required to define the global features of a protein. Characterisation of this “structural essence” has remained elusive so far: no algorithmic strategy has been devised to-date that could outperform a random selection in terms of 3D reconstruction accuracy (measured as the Ca RMSD). It is not only of theoretical interest (i.e., for design of advanced statistical potentials) to identify the number and nature of essential native contacts—such a subset of spatial constraints is very useful in a number of novel experimental methods (like EPR) which rely heavily on constraint-based protein modelling. To derive accurate three-dimensional models from distance constraints, we implemented a reconstruction pipeline using distance geometry. We selected a test-set of 12 protein structures from the four major SCOP fold classes and performed our reconstruction analysis. As a reference set, series of random subsets (ranging from 10% to 90% of native contacts) are generated for each protein, and the reconstruction accuracy is computed for each subset. We have developed a rational strategy, termed “cone-peeling” that combines sequence features and network descriptors to select minimal subsets that outperform the reference sets. We present, for the first time, a rational strategy to derive a structural essence of residue contacts and provide an estimate of the size of this minimal subset. Our algorithm computes sparse subsets capable of determining the tertiary structure at approximately 4.8 Å Ca RMSD with as little as 8% of the native contacts (Ca-Ca and Cb-Cb). At the same time, a randomly chosen subset of native contacts needs about twice as many contacts to reach the same level of accuracy. This “structural essence” opens new avenues in the fields of structure prediction, empirical potentials and docking. PMID:19997489

Predicting patterns of non-native plant invasions in Yosemite National Park, California, USA

USGS Publications Warehouse

Underwood, E.C.; Klinger, R.; Moore, P.E.

2004-01-01

One of the major issues confronting management of parks and reserves is the invasion of non-native plant species. Yosemite National Park is one of the largest and best-known parks in the United States, harbouring significant cultural and ecological resources. Effective management of non-natives would be greatly assisted by information on their potential distribution that can be generated by predictive modelling techniques. Our goal was to identify key environmental factors that were correlated with the percent cover of non-native species and then develop a predictive model using the Genetic Algorithm for Rule-set Production technique. We performed a series of analyses using community-level data on species composition in 236 plots located throughout the park. A total of 41 non-native species were recorded which occurred in 23.7% of the plots. Plots with non-natives occurred most frequently at low- to mid-elevations, in flat areas with other herbaceous species. Based on the community-level results, we selected elevation, slope, and vegetation structure as inputs into the GARP model to predict the environmental niche of non-native species. Verification of results was performed using plot data reserved from the model, which calculated the correct prediction of non-native species occurrence as 76%. The majority of the western, lower-elevation portion of the park was predicted to have relatively low levels of non-native species occurrence, with highest concentrations predicted at the west and south entrances and in the Yosemite Valley. Distribution maps of predicted occurrences will be used by management to: efficiently target monitoring of non-native species, prioritize control efforts according to the likelihood of non-native occurrences, and inform decisions relating to the management of non-native species in postfire environments. Our approach provides a valuable tool for assisting decision makers to better manage non-native species, which can be readily adapted to target non-native species in other locations.

A mechanistic assessment of seasonal microhabitat selection by drift-feeding rainbow trout Oncorhynchus mykiss in a southwestern headwater stream

USGS Publications Warehouse

Kalb, Bradley W.; Huntsman, Brock M.; Caldwell, Colleen A.; Bozek, Michael A.

2018-01-01

The positioning of fishes within a riverscape is dependent on the proximity of complementary habitats. In this study, foraging and non-foraging habitat were quantified monthly over an entire year for a rainbow trout (Oncorhynchus mykiss) population in an isolated, headwater stream in southcentral New Mexico. The stream follows a seasonal thermal and hydrologic pattern typical for a Southwestern stream and was deemed suitable for re-introduction of the native and close relative, Rio Grande cutthroat trout (O. clarkii virginalis). However, uncertainty associated with limited habitat needed to be resolved if repatriation of the native fish was to be successful. Habitat was evaluated using resource selection functions with a mechanistic drift-foraging model to explain trout distributions. Macroinvertebrate drift was strongly season- and temperature-dependent (lower in winter and spring, higher in summer and fall). Models identified stream depth as the most limiting factor for habitat selection across seasons and size-classes. Additionally, positions closer to cover were selected during the winter by smaller size-classes (0, 1, 2), while net energy intake was important during the spring for most size-classes (0, 1, 2, 3). Drift-foraging models identified that 81% of observed trout selected positions that could meet maintenance levels throughout the year. Moreover, 40% of selected habitats could sustain maximum growth. Stream positions occupied by rainbow trout were more energetically profitable than random sites regardless of season or size-class. Larger size-classes (3, 4+) were energetically more limited throughout the year than were smaller size-classes. This research suggests that habitat in the form of deep pools is of paramount importance for rainbow trout or native cutthroat trout.

English or Englishes? Outer and Expanding Circle Teachers' Awareness of and Attitudes towards Their Own Variants of English in ESL/EFL Teaching Contexts

ERIC Educational Resources Information Center

Monfared, Abbas; Khatib, Mohammad

2018-01-01

One of the challenging issues that has gained much attention, and has in fact sparked much debate, within the emergence and acquisition of World Englishes, is the Native- Non-native accent, especially its relationship with teachers' and learners' identity and selection of an appropriate pedagogic model. This paper investigates the attitudes of 260…

Chemical ecology and behavioral studies on the emerald ash borer: an update

Treesearch

Deepa Pureswaran; Therese Poland

2008-01-01

In 2006, we tested host selection and feeding preference of the emerald ash borer (EAB) on four species of ash species (green, black, white, and blue ash) that are native to North America but exotic to the beetle. For comparison, we also included Manchurian ash (which is native to the beetle) and European ash (which is exotic to the beetle) in the test. Beetles were...

Role of decaying logs and other organic seedbeds in natural regeneration of Hawaiian forest species on abandoned montane pasture

Treesearch

Paul G. Scowcroft

1992-01-01

Natural regeneration is one mechanism by which native mixed-species forests become reestablished on abandoned pasture. This study was done to determine patterns of and requirement for natural regeneration of native species in an open woodland after removal of cattle. Ten 50- by 50-m quadrats were randomly selected within a 16-ha exclosure located at 1,700-m elevation...

Intensive Selective Deer Browsing Favors Success of Asimina triloba (Paw Paw) a Native Tree Species

Treesearch

Mitchell A. Slater; Roger C. Anderson

2014-01-01

Although white-tailed deer (Odocoileus virginianus Zimmermann) are generalist herbivores, they can have significant effects on species composition and abundance of forest trees, especially when deer densities are high and most plant species are heavily browsed but a few are selectively avoided as browse. We evaluated effects of selective deer...

Trace elements in native and transplanted Fontinalis antipyretica and Platyhypnidium riparioides from rivers polluted by uranium mining.

PubMed

Kosior, Grzegorz; Steinnes, Eiliv; Samecka-Cymerman, Aleksandra; Lierhagen, Syverin; Kolon, Krzysztof; Dołhańczuk-Śródka, Agnieszka; Ziembik, Zbigniew

2017-03-01

The past uranium/polymetallic mining activities in the Sudety (SW Poland) left abandoned mines, pits, and dumps of waste rocks with trace elements and radionuclides which may erode or leach out and create a potential risk for the aquatic ecosystem, among others. In the present work four rivers affected by effluents from such mines were selected to evaluate the application of aquatic mosses for the bioindication of 56 elements. Naturally growing F. antipyretica and P. riparioides were compared with transplanted samples of the same species. The results demonstrate serious pollution of the examined rivers, especially with As, Ba, Fe, Mn, Pb, Ti, U and Zn, reaching extremely high concentrations in native moss samples. In the most polluted rivers native F. antipyretica and P. riparioides samples showed significantly higher concentrations of As, Ba, Cu, Fe, La, Nd, Ni, Pb, U and Zn than corresponding transplanted samples, whereas at less polluted sites a reverse situation was sometimes observed. Transplanted moss moved from clean to extremely polluted rivers probably protects itself against the accumulation of toxic elements by reducing their uptake. Selection of native or transplanted F. antipyretica and P. riparioides depended on the pollution load. Copyright © 2016. Published by Elsevier Ltd.

ClusPro: an automated docking and discrimination method for the prediction of protein complexes.

PubMed

Comeau, Stephen R; Gatchell, David W; Vajda, Sandor; Camacho, Carlos J

2004-01-01

Predicting protein interactions is one of the most challenging problems in functional genomics. Given two proteins known to interact, current docking methods evaluate billions of docked conformations by simple scoring functions, and in addition to near-native structures yield many false positives, i.e. structures with good surface complementarity but far from the native. We have developed a fast algorithm for filtering docked conformations with good surface complementarity, and ranking them based on their clustering properties. The free energy filters select complexes with lowest desolvation and electrostatic energies. Clustering is then used to smooth the local minima and to select the ones with the broadest energy wells-a property associated with the free energy at the binding site. The robustness of the method was tested on sets of 2000 docked conformations generated for 48 pairs of interacting proteins. In 31 of these cases, the top 10 predictions include at least one near-native complex, with an average RMSD of 5 A from the native structure. The docking and discrimination method also provides good results for a number of complexes that were used as targets in the Critical Assessment of PRedictions of Interactions experiment. The fully automated docking and discrimination server ClusPro can be found at http://structure.bu.edu

A Conceptual Characterization of Online Videos Explaining Natural Selection

ERIC Educational Resources Information Center

Bohlin, Gustav; Göransson, Andreas; Höst, Gunnar E.; Tibell, Lena A. E.

2017-01-01

Educational videos on the Internet comprise a vast and highly diverse source of information. Online search engines facilitate access to numerous videos claiming to explain natural selection, but little is known about the degree to which the video content match key evolutionary content identified as important in evolution education research. In…

A new strategy for controlling invasive weeds: selecting valuable native plants to defeat them

NASA Astrophysics Data System (ADS)

Li, Weihua; Luo, Jianning; Tian, Xingshan; Soon Chow, Wah; Sun, Zhongyu; Zhang, Taijie; Peng, Shaolin; Peng, Changlian

2015-06-01

To explore replacement control of the invasive weed Ipomoea cairica, we studied the competitive effects of two valuable natives, Pueraria lobata and Paederia scandens, on growth and photosynthetic characteristics of I. cairica, in pot and field experiments. When I. cairica was planted in pots with P. lobata or P. scandens, its total biomass decreased by 68.7% and 45.8%, and its stem length by 33.3% and 34.1%, respectively. The two natives depressed growth of the weed by their strong effects on its photosynthetic characteristics, including suppression of leaf biomass and the abundance of the CO2-fixing enzyme RUBISCO. The field experiment demonstrated that sowing seeds of P. lobata or P. scandens in plots where the weed had been largely cleared produced 11.8-fold or 2.5-fold as much leaf biomass of the two natives, respectively, as the weed. Replacement control by valuable native species is potentially a feasible and sustainable means of suppressing I. cairica.

A new strategy for controlling invasive weeds: selecting valuable native plants to defeat them

PubMed Central

Li, Weihua; Luo, Jianning; Tian, Xingshan; Soon Chow, Wah; Sun, Zhongyu; Zhang, Taijie; Peng, Shaolin; Peng, Changlian

2015-01-01

To explore replacement control of the invasive weed Ipomoea cairica, we studied the competitive effects of two valuable natives, Pueraria lobata and Paederia scandens, on growth and photosynthetic characteristics of I. cairica, in pot and field experiments. When I. cairica was planted in pots with P. lobata or P. scandens, its total biomass decreased by 68.7% and 45.8%, and its stem length by 33.3% and 34.1%, respectively. The two natives depressed growth of the weed by their strong effects on its photosynthetic characteristics, including suppression of leaf biomass and the abundance of the CO2-fixing enzyme RUBISCO. The field experiment demonstrated that sowing seeds of P. lobata or P. scandens in plots where the weed had been largely cleared produced 11.8-fold or 2.5-fold as much leaf biomass of the two natives, respectively, as the weed. Replacement control by valuable native species is potentially a feasible and sustainable means of suppressing I. cairica. PMID:26047489