Science.gov

Sample records for needfor anew strategy

  1. [Changes produce old ghosts anew--the insecure Europe].

    PubMed

    Beland, H

    1993-04-01

    Since the fall of the Berlin Wall and the collapse of existing socialist dictatorships, some of the ghosts that we thought to have long since exorcised have returned to haunt us anew-aggressive forms of nationalism, which we have turned a blind eye to for decades, and a violent species of xenophobia on occasion openly homicidal in nature are prominent features of present-day European reality. In Beland's view, such alarming phenomena can only be controlled successfully if we can contrive-both on an individual and collective plan- to de-activate the psychic mechanism of projecting our own evils and flaws onto others (i.e. "foreigners") and to achieve what Melanie Klein calls the "depressive position", i.e. attain to a higher guilt tolerance. This, Beland contends, is the central utopia of European humanism.

  2. [Changes produce old ghosts anew--the insecure Europe].

    PubMed

    Beland, H

    1993-04-01

    Since the fall of the Berlin Wall and the collapse of existing socialist dictatorships, some of the ghosts that we thought to have long since exorcised have returned to haunt us anew-aggressive forms of nationalism, which we have turned a blind eye to for decades, and a violent species of xenophobia on occasion openly homicidal in nature are prominent features of present-day European reality. In Beland's view, such alarming phenomena can only be controlled successfully if we can contrive-both on an individual and collective plan- to de-activate the psychic mechanism of projecting our own evils and flaws onto others (i.e. "foreigners") and to achieve what Melanie Klein calls the "depressive position", i.e. attain to a higher guilt tolerance. This, Beland contends, is the central utopia of European humanism. PMID:8502760

  3. Starting Anew

    ERIC Educational Resources Information Center

    Lum, Lydia

    2006-01-01

    Hundreds of higher education faculty lost their jobs in the aftermath of Hurricane Katrina. New Orleans' colleges and universities were forced to cancel fall semester classes after the city's levee system failed, submerging 80 percent of the city just weeks before the academic year began. Damage assessments began even before the deadly storm's…

  4. Nationwide Standards Eyed Anew

    ERIC Educational Resources Information Center

    Olson, Lynn

    2005-01-01

    With the federal No Child Left Behind Act underscoring the wide variation in what states demand of their students, people on both sides of the political aisle are again making the case for national standards, curricula, and tests. It wasn't so long ago--during the Clinton and George H.W. Bush administrations--that similar proposals went down in…

  5. A New Poetry Anew.

    ERIC Educational Resources Information Center

    Grumman, Bob

    1994-01-01

    Classifies the various forms that exist in a type of poetry dubbed "burstnorm" poetry, a form of lyrical poetry. Differentiates burstnorm from two other types, "plaintext" and "songmode poetry." Describes three types of burstnorm poetry: surrealistic, pluraesthetic, and language poetry. Discusses further subtypes of each form. Presents a lesson in…

  6. The Birthday Problem Anew

    ERIC Educational Resources Information Center

    Braza, Peter A.

    2006-01-01

    Accurate and accessible expressions for the probability of having a matching birthday are obtained by using Stirling's formula and Taylor series. For interest, the results are applied to the planets of our solar system.

  7. Lessons: Katrina and Beginning Anew

    ERIC Educational Resources Information Center

    Kirylo, James D.

    2005-01-01

    New Orleans, fondly known in better days for its spectacular cuisine, cool jazz, and good times, was the leading story on television news broadcasts the world over when a massive hurricane came. As Katrina took its destructive path, culminating in the devastating rupture of ill-prepared levee systems, the world was riveted by stories about the…

  8. Health and Household Air Pollution from Solid Fuel Use: The Needfor Improved Exposure Assessment

    EPA Science Inventory

    Background: Nearly half the world’s population relies on solid fuel combustion to meet basic household energy needs (e.g., cooking and heating). Resulting air pollution exposures are estimated to cause 3% of the global burden of disease. Large variability and a lack of resource...

  9. Hair analysis for Delta9-tetrahydrocannabinolic acid A--new insights into the mechanism of drug incorporation of cannabinoids into hair.

    PubMed

    Auwärter, Volker; Wohlfarth, Ariane; Traber, Jessica; Thieme, Detlef; Weinmann, Wolfgang

    2010-03-20

    Differentiation between external contamination and incorporation of drugs or their metabolites from inside the body via blood, sweat or sebum is a general issue in hair analysis and of high concern when interpreting analytical results. In hair analysis for cannabinoids the most common target is Delta9-tetrahydrocannabinol (THC), sometimes cannabidiol (CBD) and cannabinol (CBN) are determined additionally. After repeated external contamination by cannabis smoke these analytes are known to be found in hair even after performing multiple washing steps. A widely accepted strategy to unequivocally prove active cannabis consumption is the analysis of hair extracts for the oxidative metabolite 11-nor-9-carboxy-THC (THC-COOH). Although the acidic nature of this metabolite suggests a lower rate of incorporation into the hair matrix compared to THC, it is not fully understood up to now why hair concentrations of THC-COOH are generally found to be much lower (mostly <10 pg/mg) than the corresponding THC concentrations. Delta9-Tetrahydrocannabinolic acid A (THCA A) is the preliminary end product of the THC biosynthesis in the cannabis plant. Unlike THC it is non-psychoactive and can be regarded as a 'precursor' of THC being largely decarboxylated when heated or smoked. The presented work shows for the first time that THCA A is not only detectable in blood and urine of cannabis consumers but also in THC positive hair samples. A pilot experiment performed within this study showed that after oral intake of THCA A on a regular basis no relevant incorporation into hair occurred. It can be concluded that THCA A in hair almost exclusively derives from external contamination e.g. by side stream smoke. Elevated temperatures during the analytical procedure, particularly under alkaline conditions, can lead to decarboxylation of THCA A and accordingly increase THC concentrations in hair. Additionally, it has to be kept in mind that in hair samples tested positive for THCA A at least a

  10. Effect of the β-propiolactone treatment on the adsorption and fusion of influenza A/Brisbane/59/2007 and A/New Caledonia/20/1999 virus H1N1 on a dimyristoylphosphatidylcholine/ganglioside GM3 mixed phospholipids monolayer at the air-water interface.

    PubMed

    Desbat, Bernard; Lancelot, Eloïse; Krell, Tino; Nicolaï, Marie-Claire; Vogel, Fred; Chevalier, Michel; Ronzon, Frédéric

    2011-11-15

    The production protocol of many whole cell/virion vaccines involves an inactivation step with β-propiolactone (BPL). Despite the widespread use of BPL, its mechanism of action is poorly understood. Earlier work demonstrated that BPL alkylates nucleotide bases, but its interaction with proteins has not been studied in depth. In the present study we use ellipsometry to analyze the influence of BPL treatment of two H1N1 influenza strains, A/Brisbane/59/2007 and A/New Caledonia/20/1999, which are used for vaccine production on an industrial scale. Analyses were conducted using a mixed lipid monolayer containing ganglioside GM3, which functions as the viral receptor. Our results show that BPL treatment of both strains reduces viral affinity for the mixed monolayer and also diminishes the capacity of viral domains to self-assemble. In another series of experiments, the pH of the subphase was reduced from 7.4 to 5 to provoke the pH-induced conformational change of hemagglutinin, which occurs following endocytosis into the endosome. In the presence of the native virus the pH decrease caused a reduction in domain size, whereas lipid layer thickness and surface pressure were increased. These observations are consistent with a fusion of the viral membrane with the lipid monolayer. Importantly, this fusion was not observed with adsorbed inactivated virus, which indicates that BPL treatment inhibits the first step of virus-membrane fusion. Our data also indicate that BPL chemically modifies hemagglutinin, which mediates the interaction with GM3.

  11. Perceiving Learning Anew: Social Interaction, Dignity, and Educational Rights

    ERIC Educational Resources Information Center

    Espinoza, Manuel Luis; Vossoughi, Shirin

    2014-01-01

    What are the origins of educational rights? In this essay, Espinoza and Vossoughi assert that educational rights are "produced," "affirmed," and "negated" not only through legislative and legal channels but also through an evolving spectrum of educational activities embedded in everyday life. Thus, they argue that the…

  12. Multiple symbiont acquisition strategies as an adaptive mechanism in the coral Stylophora pistillata.

    PubMed

    Byler, Kristen A; Carmi-Veal, Maya; Fine, Maoz; Goulet, Tamar L

    2013-01-01

    In obligate symbioses, the host's survival relies on the successful acquisition and maintenance of symbionts. Symbionts can either be transferred from parent to offspring via direct inheritance (vertical transmission) or acquired anew each generation from the environment (horizontal transmission). With vertical symbiont transmission, progeny benefit by not having to search for their obligate symbionts, and, with symbiont inheritance, a mechanism exists for perpetuating advantageous symbionts. But, if the progeny encounter an environment that differs from that of their parent, they may be disadvantaged if the inherited symbionts prove suboptimal. Conversely, while in horizontal symbiont acquisition host survival hinges on an unpredictable symbiont source, an individual host may acquire genetically diverse symbionts well suited to any given environment. In horizontal acquisition, however, a potentially advantageous symbiont will not be transmitted to subsequent generations. Adaptation in obligate symbioses may require mechanisms for both novel symbiont acquisition and symbiont inheritance. Using denaturing-gradient gel electrophoresis and real-time PCR, we identified the dinoflagellate symbionts (genus Symbiodinium) hosted by the Red Sea coral Stylophora pistillata throughout its ontogenesis and over depth. We present evidence that S. pistillata juvenile colonies may utilize both vertical and horizontal symbiont acquisition strategies. By releasing progeny with maternally derived symbionts, that are also capable of subsequent horizontal symbiont acquisition, coral colonies may acquire physiologically advantageous novel symbionts that are then perpetuated via vertical transmission to subsequent generations. With symbiont inheritance, natural selection can act upon the symbiotic variability, providing a mechanism for coral adaptation.

  13. Cetacean Strategies.

    ERIC Educational Resources Information Center

    Gilliland, Denise DelGrosso

    1991-01-01

    Suggested are activities about whales for children in schools not near the ocean. Activities designed to pique students' interest in whales and to investigate the size, breathing, buoyancy, and feeding strategies of whales are discussed. (CW)

  14. Strategies Unlimited.

    ERIC Educational Resources Information Center

    Blaga, Jeff; And Others

    Designed primarily for teachers of students in grades 7-12, the document presents over 60 social studies teaching strategies and lesson plans. Each lesson includes an overview, grade level information, suggested course/subject matter uses, objectives, suggested materials, student materials, and an instructional plan. Lesson topics fall into the…

  15. [Potentiation strategies].

    PubMed

    Doumy, Olivier; Bennabi, Djamila; El-Hage, Wissam; Allaïli, Najib; Bation, Rémy; Bellivier, Frank; Holtzmann, Jérôme; Bubrovszky, Maxime; Camus, Vincent; Charpeaud, Thomas; Courvoisier, Pierre; d'Amato, Thierry; Garnier, Marion; Haesebaert, Frédéric; Bougerol, Thierry; Lançon, Christophe; Moliere, Fanny; Nieto, Isabel; Richieri, Raphaëlle; Saba, Ghassen; Courtet, Philippe; Vaiva, Guillaume; Leboyer, Marion; Llorca, Pierre-Michel; Aouizerate, Bruno; Haffen, Emmanuel

    2016-03-01

    Lithium is among the most classically recommended add-on therapeutic strategy for the management of depressive patients showing unsuccessful response to standard antidepressant medications. The effectiveness of the add-on strategy with lithium requires achieving plasma levels above 0.5 mEq/L. Mood-stabilizing antiepileptic drugs such as carbamazepine, valproate derivatives or lamotrigine have not demonstrated conclusive therapeutic effects for the management of depressive patients showing unsuccessful response to standard antidepressant medications. Thyroid hormones are considered among the currently recommended add-on therapeutic strategy for the management of depressive patients showing unsuccessful response to standard antidepressant medications. The effectiveness of the add-on strategy with thyroid hormones requires achieving plasma concentration of TSH close to the lower limits at the normal range (0.4 μUI/L) or even below it. Second-generation antipsychotics such as aripiprazole or quetiapine have consistently demonstrated significant therapeutic effects for the management of depressive patients showing unsuccessful response to standard antidepressant medications. Second-generation antipsychotics however require the careful monitoring of both cardiovascular and metabolic adverse effects.

  16. A new strategy for in vivo spectral editing. Application to GABA editing using selective homonuclear polarization transfer spectroscopy

    NASA Astrophysics Data System (ADS)

    Shen, Jun; Yang, Jehoon; Choi, In-Young; Li, Shizhe Steve; Chen, Zhengguang

    2004-10-01

    A novel single-shot in vivo spectral editing method is proposed in which the signal to be detected, is regenerated anew from the thermal equilibrium magnetization of a source to which it is J-coupled. The thermal equilibrium magnetization of the signal to be detected together with those of overlapping signals are suppressed by single-shot gradient dephasing prior to the signal regeneration process. Application of this new strategy to in vivo GABA editing using selective homonuclear polarization transfer allows complete suppression of overlapping creatine and glutathione while detecting the GABA-4 methylene resonance at 3.02 ppm with an editing yield similar to that of conventional editing methods. The NAA methyl group at 2.02 ppm was simultaneously detected and can be used as an internal navigator echo for correcting the zero order phase and frequency shifts and as an internal reference for concentration. This new method has been demonstrated for robust in vivo GABA editing in the rat brain and for study of GABA synthesis after acute vigabatrin administration.

  17. Implementation Strategy

    NASA Technical Reports Server (NTRS)

    1983-01-01

    Meeting the identified needs of Earth science requires approaching EOS as an information system and not simply as one or more satellites with instruments. Six elements of strategy are outlined as follows: implementation of the individual discipline missions as currently planned; use of sustained observational capabilities offered by operational satellites without waiting for the launch of new mission; put first priority on the data system; deploy an Advanced Data Collection and Location System; put a substantial new observing capability in a low Earth orbit in such a way as to provide for sustained measurements; and group instruments to exploit their capabilities for synergism; maximize the scientific utility of the mission; and minimize the costs of implementation where possible.

  18. Young Children's Partitioning Strategies.

    ERIC Educational Resources Information Center

    Charles, Kathy; Nason, Rod

    2000-01-01

    Studies knowledge of young children's partitioning strategies by setting out not only to identify new partitioning strategies, but also to develop taxonomy for classifying young children's partitioning strategies in terms of their abilities. Provides taxonomy utilizing children's informal partitioning strategies as the foundation upon which to…

  19. Reading Strategies or Comprehension Monitoring Strategies?

    ERIC Educational Resources Information Center

    Yang, Yu-Fen

    2006-01-01

    In order to probe the relationship between reading strategies and comprehension monitoring strategies and how they function to help readers in comprehension process, the present study utilizes think-aloud and retrospective verbal reports to examine 20 EFL readers' performances in reading texts. The results reveal that the engagement of reading…

  20. Lifting off the Ground to Return Anew: Mediated Praxis, Transformative Learning, and Social Design Experiments

    ERIC Educational Resources Information Center

    Gutierrez, Kris D.; Vossoughi, Shirin

    2010-01-01

    This article examines a praxis model of teacher education and advances a new method for engaging novice teachers in reflective practice and robust teacher learning. Social design experiments--cultural historical formations designed to promote transformative learning for adults and children--are organized around expansive notions of learning and…

  1. The Continual Intercomparison of Radiation Codes (CIRC) Assessing Anew the Quality of GCM Radiation Algorithms

    NASA Technical Reports Server (NTRS)

    Oreopoulos, Lazaros; Mlawer, Eli

    2010-01-01

    The simulation of changes in the Earth's climate due to solar and thermal radiative processes with global climate models (GCMs) is highly complex, depending on the parameterization of a multitude of nonlinearly coupled physical processes. In contrast, the germ of global climate change, the radiative forcing from enhanced abundances of greenhouse gases, is relatively well understood. The impressive agreement between detailed radiation calculations and highly resolved spectral radiation measurements in the thermal infrared under cloudless conditions (see, for example, Fig. 1) instills confidence in our knowledge of the sources of gaseous absorption. That the agreement spans a broad range of temperature and humidity regimes using instruments mounted on surface, aircraft, and satellite platforms not only attests to our capability to accurately calculate radiative fluxes under present conditions, but also provides confidence in the spectroscopic basis for computation of fluxes under conditions that might characterize future global climate (e.g., radiative forcing). Alas, the computational costs of highly resolved spectral radiation calculations cannot be afforded presently in GCMs. Such calculations have instead been used as the foundation for approximations implemented in fast but generally less accurate algorithms performing the needed radiative transfer (RT) calculations in GCMs. Credible climate simulations by GCMs cannot be ensured without accurate solar and thermal radiative flux calculations under all types of sky conditions: pristine cloudless, aerosol-laden, and cloudy. The need for accuracy in RT calculations is not only important for greenhouse gas forcing scenarios, but is also profoundly needed for the robust simulation of many other atmospheric phenomena, such as convective processes.

  2. WILDLIFE RESEARCH STRATEGY

    EPA Science Inventory

    This document describes a strategy for conducting wildlife effects research within the U.S. Environmental Protection Agencys (EPA) National Health and Environmental Effects Research Laboratory (NHEERL). The NHEEL wildlife research strategy is designed to address critical researc...

  3. A Shuttle evolution strategy

    NASA Technical Reports Server (NTRS)

    Teixeira, Charles; Mallini, Charles

    1989-01-01

    An overview of a potential Space Shuttle evolution strategy is presented. A Shuttle development study which reviews past and ongoing studies, implements a Shuttle Enhancement Data Base, and develops a methodology and a strawman evolution strategy is discussed. The long-term goals of a Shuttle evolution strategy, including increased reliability, lower cost, robustness, resiliency, increased capability, and assured access are addressed.

  4. Strategies Against Poverty.

    ERIC Educational Resources Information Center

    Riessman, Frank

    The major antipoverty strategies of the 1960's are analyzed--the conflict model of Alinsky, the welfare crisis approach of Cloward and Piven, and the new careers viewpoint of Riessman and Pearl. The latter strategy is said to have a greater "multiplier effect" on poverty than other approaches. Discussed are such specific strategies in the human…

  5. Online Strategy Games.

    ERIC Educational Resources Information Center

    Dye, Bryan

    2002-01-01

    A strategy game is an online interactive game that requires thinking in order to be played at its best and whose winning strategy is not obvious. Provides information on strategy games that are written in Java or JavaScript and freely available on the web. (KHR)

  6. Hydrocarbon geoscience research strategy

    SciTech Connect

    Not Available

    1990-04-01

    This document outlines a strategy for oil and gas related research focused on optimizing the economic producibility of the Nation's resources. The Hydrocarbon Geoscience Strategy was developed by the Hydrocarbon Geoscience Research Coordinating Committee of the Department of Energy (DOE). This strategy forms the basis for the development of DOE Fossil Energy's Oil Research Program Implementation Plan and Natural Gas Program Implementation Plan. 24 refs., 5 figs., 3 tabs.

  7. Strategy for the Development of a DNB Local Predictive Approach Based on Neptune CFD Software

    SciTech Connect

    Haynes, Pierre-Antoine; Peturaud, Pierre; Montout, Michael; Hervieu, Eric

    2006-07-01

    The NEPTUNE project constitutes the thermal-hydraulics part of a long-term joint development program for the next generation of nuclear reactor simulation tools. This project is being carried through by EDF (Electricite de France) and CEA (Commissariat a l'Energie Atomique), with the co-sponsorship of IRSN (Institut de Radioprotection et de Surete Nucleaire) and AREVA NP. NEPTUNE is a multi-phase flow software platform that includes advanced physical models and numerical methods for each simulation scale (CFD, component, system). NEPTUNE also provides new multi-scale and multi-disciplinary coupling functionalities. This new generation of two-phase flow simulation tools aims at meeting major industrial needs. DNB (Departure from Nucleate Boiling) prediction in PWRs is one of the high priority needs, and this paper focuses on its anticipated improvement by means of a so-called 'Local Predictive Approach' using the NEPTUNE CFD code. We firstly present the ambitious 'Local Predictive Approach' anticipated for a better prediction of DNB, i.e. an approach that intends to result in CHF correlations based on relevant local parameters as provided by the CFD modeling. The associated requirements for the two-phase flow modeling are underlined as well as those for the good level of performance of the NEPTUNE CFD code; hence, the code validation strategy based on different experimental data base types (including separated effect and integral-type tests data) is depicted. Secondly, we present comparisons between low pressure adiabatic bubbly flow experimental data obtained on the DEDALE experiment and the associated numerical simulation results. This study anew shows the high potential of NEPTUNE CFD code, even if, with respect to the aforementioned DNB-related aim, there is still a need for some modeling improvements involving new validation data obtained in thermal-hydraulics conditions representative of PWR ones. Finally, we deal with one of these new experimental data needs

  8. Let Strategies Serve Literature

    ERIC Educational Resources Information Center

    Senechal, Diana

    2011-01-01

    When the teaching of strategies for understanding literature crowds out a close reading of literary works themselves, something is amiss in language arts instruction, and students lose out. This has become the case in too many elementary and even secondary classrooms today, Senechal believes. Using a strategy-based lesson proposed by Stephanie…

  9. MERCURY RESEARCH STRATEGY.

    EPA Science Inventory

    The USEPA's ORD is pleased to announce the availability of its Mercury Research Strategy. This strategy guides ORD's mercury research program and covers the FY2001-2005 time frame. ORD will use it to prepare a multi-year mercury research implementation plan in 2001. The Mercury R...

  10. Strategies: Hostos Community College.

    ERIC Educational Resources Information Center

    James, Selena; And Others

    1991-01-01

    Established as an institution dedicated to the urban poor, Hostos Community College (New York) has developed innovative strategies in dental hygiene education for the aspiring but academically deficient student and the compromised student with other obligations. Strategies used include remediation, innovative curricula, and recruitment tools. (MSE)

  11. Cooperative Learning Strategies.

    ERIC Educational Resources Information Center

    Barnes, Buckley; O'Farrell, Gail

    1990-01-01

    Presents essential characteristics and types of cooperative learning strategies for use in elementary social studies. Outlines exercises for forming teams and building team spirit. Points out such methods promote group interdependence and student responsibility for learning and teaching others. Highlights two cooperative group strategies, Jigsaw…

  12. Intervention Practices & Strategies.

    ERIC Educational Resources Information Center

    North Carolina State Dept. of Public Instruction, Raleigh. Div. of School Improvement.

    This document is designed as a resource to assist North Carolina schools in providing the best programs and strategies in the areas of acceleration, remediation, and intervention. The best practices described here are applicable to most students, including students with disabilities. The programs and strategies were validated as effective by the…

  13. Integrating Technology: Strategies.

    ERIC Educational Resources Information Center

    Kercher, Lydia

    Developed by participants in an inservice workshop at the University of Wyoming, this manual lists 26 educational strategies that make use of current educational technologies, their corresponding skill development, and the content areas involved. For example, one strategy listed is to have students create their own letterhead to be used throughout…

  14. Wildfire Prevention Strategies.

    ERIC Educational Resources Information Center

    National Wildlife Coordinating Group, Boise, ID.

    This document provides information and guidance on wildfire prevention strategies. Chapters include: (1) "Introduction"; (2) "How to Use this Guide"; (3) "Fire Cause Classification"; (4) "Relative Effectiveness"; (5) "Degree of Difficulty"; (6) "Intervention Techniques"; (7) "Prevention Activities"; (8) "Sample Prevention Strategies"; and (9)…

  15. Methods & Strategies: I Wonder...

    ERIC Educational Resources Information Center

    Stevenson, Anne

    2013-01-01

    "I Wonder" boards are a teaching strategy that can be used in the classroom, as well as during science learning opportunities in nonformal settings, such as after-school science programs or summer camps.This simple strategy has led to deeper science exploration in 4-H, as young people learn alongside program staff, teachers, or…

  16. Strategies for Competitive Volleyball.

    ERIC Educational Resources Information Center

    Fraser, Stephen D.

    This book deals with strategies and team tactics involved in the game of volleyball. It is not intended to be an instructional book on how to execute the various skills required to play volleyball but instead endeavors to detail and explain basic tactics and strategies involved in volleyball team play. Each chapter deals with major areas of team…

  17. Strategy as simple rules.

    PubMed

    Eisenhardt, K M; Sull, D N

    2001-01-01

    The success of Yahoo!, eBay, Enron, and other companies that have become adept at morphing to meet the demands of changing markets can't be explained using traditional thinking about competitive strategy. These companies have succeeded by pursuing constantly evolving strategies in market spaces that were considered unattractive according to traditional measures. In this article--the third in an HBR series by Kathleen Eisenhardt and Donald Sull on strategy in the new economy--the authors ask, what are the sources of competitive advantage in high-velocity markets? The secret, they say, is strategy as simple rules. The companies know that the greatest opportunities for competitive advantage lie in market confusion, but they recognize the need for a few crucial strategic processes and a few simple rules. In traditional strategy, advantage comes from exploiting resources or stable market positions. In strategy as simple rules, advantage comes from successfully seizing fleeting opportunities. Key strategic processes, such as product innovation, partnering, or spinout creation, place the company where the flow of opportunities is greatest. Simple rules then provide the guidelines within which managers can pursue such opportunities. Simple rules, which grow out of experience, fall into five broad categories: how- to rules, boundary conditions, priority rules, timing rules, and exit rules. Companies with simple-rules strategies must follow the rules religiously and avoid the temptation to change them too frequently. A consistent strategy helps managers sort through opportunities and gain short-term advantage by exploiting the attractive ones. In stable markets, managers rely on complicated strategies built on detailed predictions of the future. But when business is complicated, strategy should be simple. PMID:11189455

  18. The chief strategy officer.

    PubMed

    Breene, R Timothy S; Nunes, Paul F; Shill, Walter E

    2007-10-01

    They're nominally and ultimately responsible for strategy, but today's CEOs have less and less time to devote to it. As a result, CEOs are appointing "chief strategy officers"--executives specifically tasked with creating, communicating, executing, and sustaining a company's strategic initiatives. In this article, three authors from Accenture share the results of their research on this emerging organizational role. The typical CSO or top strategy executive is not a pure strategist, conducting long-range planning in relative isolation. Most CSOs consider themselves doers first, with the mandate, credentials, and desire to act as well as advise. They are seasoned executives with a strong strategy orientation who have usually worn many operations hats before taking on the role. Strategy executives are charged with three critical jobs that together form the very definition of strategy execution. First, they must clarify the company's strategy for themselves and for every business unit and function, ensuring that all employees understand the details of the strategic plan and how their work connects to corporate goals. Second, CSOs must drive immediate change. The focus of the job almost always quickly evolves from creating shared alignment around a vision to riding herd on the ensuing change effort. Finally, a CSO must drive decision making that sustains organizational change. He or she must be that person who, in the CEO's stead, can walk into any office and test whether the decisions being made are aligned with the strategy and are creating the desired results. When decisions below the executive suite aren't being made in accordance with strategy, much of the CSO's job involves learning why and quickly determining whether to stay the course or change tack.

  19. Typhoid fever vaccination strategies.

    PubMed

    Date, Kashmira A; Bentsi-Enchill, Adwoa; Marks, Florian; Fox, Kimberley

    2015-06-19

    Typhoid vaccination is an important component of typhoid fever prevention and control, and is recommended for public health programmatic use in both endemic and outbreak settings. We reviewed experiences with various vaccination strategies using the currently available typhoid vaccines (injectable Vi polysaccharide vaccine [ViPS], oral Ty21a vaccine, and injectable typhoid conjugate vaccine [TCV]). We assessed the rationale, acceptability, effectiveness, impact and implementation lessons of these strategies to inform effective typhoid vaccination strategies for the future. Vaccination strategies were categorized by vaccine disease control strategy (preemptive use for endemic disease or to prevent an outbreak, and reactive use for outbreak control) and vaccine delivery strategy (community-based routine, community-based campaign and school-based). Almost all public health typhoid vaccination programs used ViPS vaccine and have been in countries of Asia, with one example in the Pacific and one experience using the Ty21a vaccine in South America. All vaccination strategies were found to be acceptable, feasible and effective in the settings evaluated; evidence of impact, where available, was strongest in endemic settings and in the short- to medium-term. Vaccination was cost-effective in high-incidence but not low-incidence settings. Experience in disaster and outbreak settings remains limited. TCVs have recently become available and none are WHO-prequalified yet; no program experience with TCVs was found in published literature. Despite the demonstrated success of several typhoid vaccination strategies, typhoid vaccines remain underused. Implementation lessons should be applied to design optimal vaccination strategies using TCVs which have several anticipated advantages, such as potential for use in infant immunization programs and longer duration of protection, over the ViPS and Ty21a vaccines for typhoid prevention and control.

  20. Effective Search Strategies.

    ERIC Educational Resources Information Center

    Hlava, Marjorie M. K.; Knox, Douglas R.

    1979-01-01

    Discusses problem preparation and specification along with search strategies and techniques employed by an information scientist in assisting users of on-line data bases, and briefly reviews ways to save computer time. (CWM)

  1. Strategies for Success

    ERIC Educational Resources Information Center

    Tedrick, Lou; Sumsion, Zach; Smith, Mary; Cutshall, Charlie

    2012-01-01

    "Training" magazine taps 2012 Training Top 125 winners and Top 10 Hall of Famers to provide their learning and development best practices in each issue. This article looks at strategies to foster technology innovation and implementation and onboarding.

  2. Management strategies for fibromyalgia

    PubMed Central

    Le Marshall, Kim Francis; Littlejohn, Geoffrey Owen

    2011-01-01

    Clinical question What are the effective, evidence-based strategies available for the management of fibromyalgia? Conclusion There are a number of management strategies available with robust evidence to support their use in clinical practice. Definition Fibromyalgia is a complex pain syndrome characterized by widespread, chronic muscular pain and tenderness, disordered sleep, emotional distress, cognitive disturbance, and fatigue. Its prevalence is estimated to be 3%–5% in the population and higher yet in patients with comorbid rheumatic diseases. Level of evidence Systematic reviews, meta-analyses, randomized controlled trials (RCTs). Search sources PubMed, Cochrane Library, manual search Consumer summary Key messages for patients and clinicians are: There are many effective pharmacological management strategies available for fibromyalgia.A nonpharmacological, multicomponent approach utilizing education, aerobic exercise, psychological therapy, and other strategies is also effective for fibromyalgia.Despite the significant and, at times, disabling physical and psychological symptoms, fibromyalgia can be a manageable condition with a potentially good outcome.

  3. 'Net Search Strategies.

    ERIC Educational Resources Information Center

    Bell, Suzanne S.

    1997-01-01

    Provides strategies for effective Internet searches. Categorizes queries into four types and describes tools: subject lists; indexes/directories; keyword search engines; Usenet newsgroups; and special purpose search tools. Discusses the importance of deciphering information and adjusting to changes. (AEF)

  4. Strategies for Effective Outsourcing.

    ERIC Educational Resources Information Center

    Moneta, Larry; Dillon, William L.

    2001-01-01

    Emphasizes strategies that can be employed for effective outsourcing in higher education settings. Several models of outsourcing are identified and described, and examples of institutions using each model are provided. (GCP)

  5. WASTE RESEARCH STRATEGY

    EPA Science Inventory

    The Waste Research Strategy covers research necessary to support both the proper management of solid and hazardous wastes and the effective remediation of contaminated waste sites. This research includes improving the assessment of existing environmental risks, as well as develop...

  6. Children's Strategies in Measurement.

    ERIC Educational Resources Information Center

    Gholam, Ghada Khoury

    1994-01-01

    Discusses some results of the CSMS test which provides information for teachers on students' levels of understanding in secondary school mathematics, including comparison with a Piagetian task, identification of misconceptions, and description of naive strategies. (MKR)

  7. Quantitative Glycomics Strategies*

    PubMed Central

    Mechref, Yehia; Hu, Yunli; Desantos-Garcia, Janie L.; Hussein, Ahmed; Tang, Haixu

    2013-01-01

    The correlations between protein glycosylation and many biological processes and diseases are increasing the demand for quantitative glycomics strategies enabling sensitive monitoring of changes in the abundance and structure of glycans. This is currently attained through multiple strategies employing several analytical techniques such as capillary electrophoresis, liquid chromatography, and mass spectrometry. The detection and quantification of glycans often involve labeling with ionic and/or hydrophobic reagents. This step is needed in order to enhance detection in spectroscopic and mass spectrometric measurements. Recently, labeling with stable isotopic reagents has also been presented as a very viable strategy enabling relative quantitation. The different strategies available for reliable and sensitive quantitative glycomics are herein described and discussed. PMID:23325767

  8. Possible funding strategies

    NASA Technical Reports Server (NTRS)

    Davidson, T. F.

    1991-01-01

    Funding strategies are examined for the AIA rocket propulsion strategic plan. Either the government, industry, or universities can fund the project alone, or it was concluded, it works best if is a combination of these sources.

  9. Social strategies that work.

    PubMed

    Piskorski, Mikołaj Jan

    2011-11-01

    Although most companies have collected lots of friends and followers on social platforms such as Facebook, few have succeeded in generating profits there. That's because they merely port their digital strategies into social environments by broadcasting their commercial messages or seeking customer feedback. To succeed on social platforms, says Harvard Business School's Piskorski, businesses need to devise social strategies that are consistent with users' expectations and behavior in these venues--namely, people want to connect with other people, not with companies. The author defines successful social strategies as those that reduce costs or increase customers' willingness to pay by helping people establish or strengthen relationships through doing free work on a company's behalf. Citing successes at Zynga, eBay, American Express, and Yelp, Piskorski shows that social strategies can generate profits by helping people connect in exchange for tasks that benefit the company such as customer acquisition, marketing, and content creation. He lays out a systematic way to build a social strategy and shows how a major credit card company he advised used the method to roll out its own strategy. PMID:22111430

  10. Social strategies that work.

    PubMed

    Piskorski, Mikołaj Jan

    2011-11-01

    Although most companies have collected lots of friends and followers on social platforms such as Facebook, few have succeeded in generating profits there. That's because they merely port their digital strategies into social environments by broadcasting their commercial messages or seeking customer feedback. To succeed on social platforms, says Harvard Business School's Piskorski, businesses need to devise social strategies that are consistent with users' expectations and behavior in these venues--namely, people want to connect with other people, not with companies. The author defines successful social strategies as those that reduce costs or increase customers' willingness to pay by helping people establish or strengthen relationships through doing free work on a company's behalf. Citing successes at Zynga, eBay, American Express, and Yelp, Piskorski shows that social strategies can generate profits by helping people connect in exchange for tasks that benefit the company such as customer acquisition, marketing, and content creation. He lays out a systematic way to build a social strategy and shows how a major credit card company he advised used the method to roll out its own strategy.

  11. What's wrong with strategy?

    PubMed

    Campbell, A; Alexander, M

    1997-01-01

    Why is it that successful strategies are rarely developed as a result of formal planning processes? What is wrong with the way most companies go about developing strategy? Andrew Campbell and Marcus Alexander take a common sense look at why the planning frameworks managers use so often yield disappointing results. Companies often fail to distinguish between purpose (what an organization exists to do) and constraints (what an organization must do in order to survive), the authors say. Many executives mistakenly believe, for example, that satisfying stakeholders is an objective that drives thinking about strategy. In fact, it's a constraint, not an objective. Companies that don't win the loyalty of stakeholders will go out of business. Strategy is not about plans but about insights, the authors add. Strategy development is the process of discovering and understanding insights and should not be confused with planning, which is about turning insights into action. Furthermore, because executives develop most of their insights while actually doing the real work of running a business, it is important for companies not to separate strategy development from implementation. Is there a better way? The answer is not new planning processes or more effort. Instead, managers must understand two fundamental points: the benefit of having a well-articulated, stable purpose and the importance of discovering, understanding, documenting, and exploiting insights about how to create value.

  12. Creative critical-thinking strategies.

    PubMed

    Chubinski, S

    1996-01-01

    Are you looking for strategies to teach critical thinking? The author presents a variety of quick, creative strategies to facilitate teaching critical-thinking skills. These strategies engage students in their learning and are adaptable to any nursing course.

  13. Strategy as revolution.

    PubMed

    Hamel, G

    1996-01-01

    How often does the strategic-planning process start with senior executives asking what the rest of the organization can teach them about the future? Not often enough, argues Gary Hamel. In many companies, strategy making is an elitist procedure and ¿strategy¿ consists of nothing more than following the industry's rules. But more and more companies, intent on overturning the industrial order, are rewriting those rules. What can industry incumbents do? Either surrender the future to revolutionary challengers or revolutionize the way their companies create strategy. What is needed is not a tweak to the traditional strategic-planning process, Hamel says, but a new philosophical foundation: strategy is revolution. Hamel offers ten principles to help a company think about the challenge of creating truly revolutionary strategies. Perhaps the most fundamental principle is that so-called strategic planning doesn't produce true strategic innovation. The traditional planning process is little more than a rote procedure in which deeply held assumptions and industry conventions are reinforced rather than challenged. Such a process harnesses only a tiny proportion of an organization's creative potential. If there is to be any hope of industry revolution, senior managers must give up their monopoly on the creation of strategy. They must embrace a truly democratic process that can give voice to the revolutionaries that exist in every company. If senior managers are unwilling to do this, employees must become strategy activists. The opportunities for industry revolution are mostly unexplored. One thing is certain: if you don't let the revolutionaries challenge you from within, they will eventually challenge you from without--in the marketplace.

  14. Comprehensive national energy strategy

    SciTech Connect

    1998-04-01

    This Comprehensive National Energy Strategy sets forth a set of five common sense goals for national energy policy: (1) improve the efficiency of the energy system, (2) ensure against energy disruptions, (3) promote energy production and use in ways that respect health and environmental values, (4) expand future energy choices, and (5) cooperate internationally on global issues. These goals are further elaborated by a series of objectives and strategies to illustrate how the goals will be achieved. Taken together, the goals, objectives, and strategies form a blueprint for the specific programs, projects, initiatives, investments, and other actions that will be developed and undertaken by the Federal Government, with significant emphasis on the importance of the scientific and technological advancements that will allow implementation of this Comprehensive National Energy Strategy. Moreover, the statutory requirement of regular submissions of national energy policy plans ensures that this framework can be modified to reflect evolving conditions, such as better knowledge of our surroundings, changes in energy markets, and advances in technology. This Strategy, then, should be thought of as a living document. Finally, this plan benefited from the comments and suggestions of numerous individuals and organizations, both inside and outside of government. The Summary of Public Comments, located at the end of this document, describes the public participation process and summarizes the comments that were received. 8 figs.

  15. Fault Management Design Strategies

    NASA Technical Reports Server (NTRS)

    Day, John C.; Johnson, Stephen B.

    2014-01-01

    Development of dependable systems relies on the ability of the system to determine and respond to off-nominal system behavior. Specification and development of these fault management capabilities must be done in a structured and principled manner to improve our understanding of these systems, and to make significant gains in dependability (safety, reliability and availability). Prior work has described a fundamental taxonomy and theory of System Health Management (SHM), and of its operational subset, Fault Management (FM). This conceptual foundation provides a basis to develop framework to design and implement FM design strategies that protect mission objectives and account for system design limitations. Selection of an SHM strategy has implications for the functions required to perform the strategy, and it places constraints on the set of possible design solutions. The framework developed in this paper provides a rigorous and principled approach to classifying SHM strategies, as well as methods for determination and implementation of SHM strategies. An illustrative example is used to describe the application of the framework and the resulting benefits to system and FM design and dependability.

  16. Modified Cognitive Strategy Instruction: An Expository Writing Strategy

    ERIC Educational Resources Information Center

    Guzel-Ozmen, Ruya

    2009-01-01

    In this article, modified cognitive strategy instruction in writing (CSIW), a cognitive strategy instructional model is described. Modified CSIW was designed based on two effective instructional models: cognitive strategy instruction in writing (CSIW) and self-regulated strategy development (SRSD). Modified CSIW provides tailored instruction to…

  17. Language Learning Strategies and Communication Strategies: A Synthesis

    ERIC Educational Resources Information Center

    Husain, Kausar

    2006-01-01

    Since Selinker's (1972) historic invocation of language learning strategies (LLS) and communication strategies (CS) as two distinct processes involved in the development of interlanguage, it has become customary in SLA literature to distinguish the strategies of learning from the strategies of communication. It has been argued in this article that…

  18. Strategy under uncertainty.

    PubMed

    Courtney, H; Kirkland, J; Viguerie, P

    1997-01-01

    At the heart of the traditional approach to strategy lies the assumption that by applying a set of powerful analytic tools, executives can predict the future of any business accurately enough to allow them to choose a clear strategic direction. But what happens when the environment is so uncertain that no amount of analysis will allow us to predict the future? What makes for a good strategy in highly uncertain business environments? The authors, consultants at McKinsey & Company, argue that uncertainty requires a new way of thinking about strategy. All too often, they say, executives take a binary view: either they underestimate uncertainty to come up with the forecasts required by their companies' planning or capital-budging processes, or they overestimate it, abandon all analysis, and go with their gut instinct. The authors outline a new approach that begins by making a crucial distinction among four discrete levels of uncertainty that any company might face. They then explain how a set of generic strategies--shaping the market, adapting to it, or reserving the right to play at a later time--can be used in each of the four levels. And they illustrate how these strategies can be implemented through a combination of three basic types of actions: big bets, options, and no-regrets moves. The framework can help managers determine which analytic tools can inform decision making under uncertainty--and which cannot. At a broader level, it offers executives a discipline for thinking rigorously and systematically about uncertainty and its implications for strategy.

  19. Successful product realization strategies

    NASA Astrophysics Data System (ADS)

    Peeples, John; Boulton, William R.

    1995-02-01

    Product realization is the process of defining, designing, developing, and delivering products to the market. While the main thrust of this JTEC panel was to conduct a complete investigation of the state of Japanese low-cost electronic packaging technologies, it is very difficult to totally separate the development of technology and products from the product realization process. Japan's electronics firms adhere to a product realization strategy based on a strong customer focus, a consistent commitment to excellence in design, and a cost-effective approach to technology commercialization. The Japanese product-pull strategy has been a successful driver and influencing factor in every aspect of the product development cycle.

  20. Improving immunization strategies

    NASA Astrophysics Data System (ADS)

    Gallos, Lazaros K.; Liljeros, Fredrik; Argyrakis, Panos; Bunde, Armin; Havlin, Shlomo

    2007-04-01

    We introduce an immunization method where the percentage of required vaccinations for immunity are close to the optimal value of a targeted immunization scheme of highest degree nodes. Our strategy retains the advantage of being purely local, without the need for knowledge on the global network structure or identification of the highest degree nodes. The method consists of selecting a random node and asking for a neighbor that has more links than himself or more than a given threshold and immunizing him. We compare this method to other efficient strategies on three real social networks and on a scale-free network model and find it to be significantly more effective.

  1. Strategies for dracunculiasis eradication.

    PubMed Central

    Hopkins, D. R.; Ruiz-Tiben, E.

    1991-01-01

    In 1991 the Forty-fourth World Health Assembly declared the goal of eradicating dracunculiasis (guinea worm disease) by the end of 1995. This article summarizes the recommended strategies for surveillance and interventions in national dracunculiasis eradication programmes. It is based on personal experience with dracunculiasis programmes in Ghana, Nigeria and Pakistan. Three phases are described: establishment of a national programme office and conduct of a baseline survey; implementation of interventions; and case containment. The relevance of dracunculiasis eradication activities to strengthening of primary health care in the three countries is discussed briefly. Similar strategies would help eradicate this disease in the remaining endemic countries. PMID:1835673

  2. Successful product realization strategies

    NASA Technical Reports Server (NTRS)

    Peeples, John; Boulton, William R.

    1995-01-01

    Product realization is the process of defining, designing, developing, and delivering products to the market. While the main thrust of this JTEC panel was to conduct a complete investigation of the state of Japanese low-cost electronic packaging technologies, it is very difficult to totally separate the development of technology and products from the product realization process. Japan's electronics firms adhere to a product realization strategy based on a strong customer focus, a consistent commitment to excellence in design, and a cost-effective approach to technology commercialization. The Japanese product-pull strategy has been a successful driver and influencing factor in every aspect of the product development cycle.

  3. Essays on strategy VII

    SciTech Connect

    Gill, T.C.

    1990-01-01

    Revolutionary developments in Europe and their global reverberations since 1989 have affected certain aspects of our national strategy. This volume presents nine essays dealing imaginatively with the issues of the post-Cold War period. One of them addresses general US strategy for the 1990s. Three focus on high-level strategic matters: the future of flexible response, antisatellite weapons, and forward, mobile defenses. The others address US chemical weapons policy, use of civilian aircraft for defense airlift, neutrality of the Panama Canal after 1999, arms sales by China, and strategic defense at reduced cost.

  4. Prodrug Strategies for Paclitaxel.

    PubMed

    Meng, Ziyuan; Lv, Quanxia; Lu, Jun; Yao, Houzong; Lv, Xiaoqing; Jiang, Feng; Lu, Aiping; Zhang, Ge

    2016-01-01

    Paclitaxel is an anti-tumor agent with remarkable anti-tumor activity and wide clinical uses. However, it is also faced with various challenges especially for its poor water solubility and low selectivity for the target. To overcome these disadvantages of paclitaxel, approaches using small molecule modifications and macromolecule modifications have been developed by many research groups from all over the world. In this review, we discuss the different strategies especially prodrug strategies that are currently used to make paclitaxel more effective. PMID:27223283

  5. A new clustering strategy

    NASA Astrophysics Data System (ADS)

    Feng, Jian-xin; Tang, Jia-fu; Wang, Guang-xing

    2007-04-01

    On the basis of the analysis of clustering algorithm that had been proposed for MANET, a novel clustering strategy was proposed in this paper. With the trust defined by statistical hypothesis in probability theory and the cluster head selected by node trust and node mobility, this strategy can realize the function of the malicious nodes detection which was neglected by other clustering algorithms and overcome the deficiency of being incapable of implementing the relative mobility metric of corresponding nodes in the MOBIC algorithm caused by the fact that the receiving power of two consecutive HELLO packet cannot be measured. It's an effective solution to cluster MANET securely.

  6. Prodrug Strategies for Paclitaxel

    PubMed Central

    Meng, Ziyuan; Lv, Quanxia; Lu, Jun; Yao, Houzong; Lv, Xiaoqing; Jiang, Feng; Lu, Aiping; Zhang, Ge

    2016-01-01

    Paclitaxel is an anti-tumor agent with remarkable anti-tumor activity and wide clinical uses. However, it is also faced with various challenges especially for its poor water solubility and low selectivity for the target. To overcome these disadvantages of paclitaxel, approaches using small molecule modifications and macromolecule modifications have been developed by many research groups from all over the world. In this review, we discuss the different strategies especially prodrug strategies that are currently used to make paclitaxel more effective. PMID:27223283

  7. Strategies for Teaching Geometry to Younger Children.

    ERIC Educational Resources Information Center

    Fielker, David S.

    1979-01-01

    Topics discussed include: reasons for strategies; the use of a hierarchy of spaces from topological to Euclidean in teaching; structural strategies; pedagogical strategies; and mathematical strategies. (MP)

  8. Strategies for Reallocation.

    ERIC Educational Resources Information Center

    Newton, Robert R.

    2000-01-01

    Offers colleges and universities some strategies when reallocation of funds is necessary. Discussion focuses on the use of facilitating teams to help department chairpersons, active promotion of reallocation in funding proposals, use of analytical databases in decision making, use of program audits, taxation policies, decentralization of decision…

  9. Developing an Information Strategy

    ERIC Educational Resources Information Center

    Hanson, Terry

    2011-01-01

    The purpose of an information strategy is to highlight the extent to which a modern, complex organization depends on information, in all of its guises, and to consider how this strategic asset should be managed. This dependency has always been present and nowhere more so than in universities, whose very purpose is built around information and its…

  10. Strategies for Social Studies.

    ERIC Educational Resources Information Center

    Miller, Fred

    Past research recommends emphasis upon the development of thinking as a curricular objective and the use of Hilda Taba's teaching strategies for developing children's thinking. The purpose of this ESEA Title 3 in-service program was to produce teachers who could plan, implement, and evaluate teaching activities for each of Taba's cognitive tasks,…

  11. Campus Computing Strategies.

    ERIC Educational Resources Information Center

    McCredie, John W., Ed.

    Ten case studies that describe the planning process and strategies employed by colleges who use computing and communication systems are presented, based on a 1981-1982 study conducted by EDUCOM. An introduction by John W. McCredie summarizes several current and future effects of the rapid spread and integration of computing and communication…

  12. Environmental Education Strategy

    ERIC Educational Resources Information Center

    Bootrach, Pradit; Thiengkamol, Nongnapas; Thiengkamol, Tanarat Khoowaranyoo

    2015-01-01

    Data was collected from 403 primary school administrators in Maha Sarakham Province, Thailand, to develop causal relationship model of Administrator Characteristics (AC), Teacher Characteristics (TC) and Environmental Education Principle (EE) that affect Environmental Education Strategy (EES) through Inspiration of Public Mind for Environmental…

  13. Avian influenza control strategies

    Technology Transfer Automated Retrieval System (TEKTRAN)

    Control strategies for avian influenza in poultry vary depending on whether the goal is prevention, management, or eradication. Components used in control programs include: 1) education which includes communication, public awareness, and behavioral change, 2) changes to production and marketing sys...

  14. World Energy Strategies

    ERIC Educational Resources Information Center

    Lovins, Amory B.

    1974-01-01

    Examines possible energy options and outlines assessments and conclusions influencing recent top level energy thinking and planning. Indicates that no nation on earth appears to have either a coherent long-range energy strategy or the institutions needed to devise one. (JR)

  15. Young Children's Combinatoric Strategies.

    ERIC Educational Resources Information Center

    English, Lyn D.

    1991-01-01

    Fifty children, ranging in age from 4 to 10, were individually administered a series of tasks involving different combinations of 2 items selected from a discrete set of items. Analyses of their performances revealed a series of six, increasingly sophisticated, solution strategies ranging from random number selection of items to a systematic…

  16. Strategies for Teen Readers

    ERIC Educational Resources Information Center

    Coutant, Carolyn; Perchemlides, Natalia

    2005-01-01

    Genre-specific reading or comprehension strategies can help older, striving students comprehend expository and narrative texts. Students being taught to be strategic and methodical in their approach can create a generation of readers, who will be able to apply their critical thinking skills to any piece of text they encounter.

  17. Prereaders' Story Processing Strategies.

    ERIC Educational Resources Information Center

    Harlin, Rebecca P.

    A study examined prereaders' story processing strategies by assessing their performance on tasks that tapped their ability to (1) use story grammar and role playing, (2) retell a wordless picture book, (3) read a predictable book, (4) retell an oral story, (5) sequence pictured story events, and (6) fingerpoint-read a nursery rhyme. Parent…

  18. Novel antitussive strategies.

    PubMed

    Morjaria, Jaymin B; Dickinson, Rebecca S; Morice, Alyn H

    2013-04-01

    Acute and chronic cough represent one of the most common symptoms of medical importance but effective pharmacotherapy is, to all intents and purposes, absent. Numerous initiatives targeting the recently discovered tussive pathways are in progress. Here, we review the current antitussive armamentarium and provide an update on the novel strategies and compounds in development.

  19. [Inquiry Teaching Strategies.

    ERIC Educational Resources Information Center

    Strasser, Ben B.; Dalis, Gus T.

    The DALSTRA (DALis/STRAsser) Inquiry Teaching Strategy is a model of teacher behaviors regarding teaching as a process composed of three categories of actions: basic behaviors, goal-directed behaviors, and diagnostic behaviors. The materials in this document were designed for use in an inservice education program in DALSTRA inquiry methods, and…

  20. Facilitative Strategies in Action.

    ERIC Educational Resources Information Center

    Fuller, Thara M. A.; Haugabrook, Adrian K.

    2001-01-01

    Describes campus-based strategies to facilitate collaboration by examining the process of restructuring a division of student affairs as an educational partner with academic affairs. Describes three collaborative efforts at the University of Massachusetts Boston: the Beacon Leadership Project, the Diversity Research Initiative, and the Beacon…

  1. Marking Strategies in Italy.

    ERIC Educational Resources Information Center

    Gattullo, Mario

    1987-01-01

    Three types of student evaluation strategies used in Italy are described: (1) teacher's free comments; (2) standardized adjectives used as rating scales; and (3) numeric scores based on tests and other evaluation criteria. Implications of the third approach, which was implemented according to legislation in 1977, are discussed. (GDC)

  2. NASA science communications strategy

    NASA Technical Reports Server (NTRS)

    1995-01-01

    In 1994, the Clinton Administration issued a report, 'Science in the National Interest', which identified new national science goals. Two of the five goals are related to science communications: produce the finest scientists and engineers for the 21st century, and raise scientific and technological literacy of all Americans. In addition to the guidance and goals set forth by the Administration, NASA has been mandated by Congress under the 1958 Space Act to 'provide for the widest practicable and appropriate dissemination concerning its activities and the results thereof'. In addition to addressing eight Goals and Plans which resulted from a January 1994 meeting between NASA and members of the broader scientific, education, and communications community on the Public Communication of NASA's Science, the Science Communications Working Group (SCWG) took a comprehensive look at the way the Agency communicates its science to ensure that any changes the Agency made were long-term improvements. The SCWG developed a Science Communications Strategy for NASA and a plan to implement the Strategy. This report outlines a strategy from which effective science communications programs can be developed and implemented across the agency. Guiding principles and strategic themes for the strategy are provided, with numerous recommendations for improvement discussed within the respective themes of leadership, coordination, integration, participation, leveraging, and evaluation.

  3. Nitric oxide inhibition strategies

    PubMed Central

    Wong, Vivian (Wai Chong); Lerner, Ethan

    2015-01-01

    Nitric oxide is involved in many physiologic processes. There are efforts, described elsewhere in this volume, to deliver nitric oxide to tissues as a therapy. Nitric oxide also contributes to pathophysiologic processes. Inhibiting nitric oxide or its production can thus also be of therapeutic benefit. This article addresses such inhibitory strategies. PMID:26634146

  4. Technology Planning Strategies

    ERIC Educational Resources Information Center

    Decker, Kathy

    2004-01-01

    Effective planning strategies drive achievement of an overall technology goal to increase access to electronic information in real time in order to increase efficiency, productivity, and communication across campus. Planning relies on providing access, 'Anytime Anywhere' to student information, calendar, email, course management tools, and the…

  5. Intermittent search strategies

    NASA Astrophysics Data System (ADS)

    Bénichou, Olivier; Voituriez, Raphael

    2015-10-01

    The following sections are included: * Introduction * Animals looking for food * Model of intermittent search * Minimizing the search time * Should animals really perform Lévy strategies? * How does a protein find its target sequence on DNA? * Active intermittent transport in cells * Optimizing the kinetic rate constant * Robustness of the results * Conclusion * Bibliography

  6. Motivational Strategies That Work!

    ERIC Educational Resources Information Center

    Educators' Spotlight Digest, 2009

    2009-01-01

    This article presents K-12 motivational strategies that focus on different ideas school library media specialists can use to gain and sustain attention in the research topic. Some have come from recent submissions to the S.O.S. database of lesson plans and teaching ideas. A student-directed searching activity for college level library instruction…

  7. Effective Strategies for Reallocation.

    ERIC Educational Resources Information Center

    Hyatt, James A.

    1984-01-01

    Strategies for reallocation of resources that were used by five public colleges are discussed. Attention is directed to the efforts of institutions that are under severe political, economic, and time pressure. At each of the following schools that were visited, meetings were held with key administrators, faculty members, and students: the…

  8. NASA Education Communication Strategy

    ERIC Educational Resources Information Center

    National Aeronautics and Space Administration (NASA), 2008

    2008-01-01

    For the past 15 years, the number of American college students earning science, technology, engineering, and mathematics (STEM) degrees has continued to decrease. By 2010, it is projected the national demand for STEM employees will rise by 10 percent. The Education Communication Strategy identifies the steps National Aeronautics and Space…

  9. Strategy Retooled at Gates

    ERIC Educational Resources Information Center

    Robelen, Erik W.

    2008-01-01

    In rolling out plans last week to revamp its high school strategy and launch a major new effort on the postsecondary front, the Bill & Melinda Gates Foundation is undertaking a more sweeping approach to grantmaking that appears aimed at reshaping some core elements of the U.S. education system. The philanthropy's agenda on secondary schools…

  10. Strategies in transition

    NASA Technical Reports Server (NTRS)

    Diaz, Alphonso V.

    1993-01-01

    A new vision has emerged within the Office of Space Science and Applications (OSSA), and within the agency as a whole, for how to design missions to be responsive to the changing budget environment of the 1990s. The overall space science and applications program had to be looked at, restructuring the most expensive and complex projects to bring down costs and ensure their place in the mission queue of the future. The recent restructuring of some of OSSA's largest programs in development and the work to improve efficiency for those in operation is part of OSSA's effort to free funds for more frequent space science missions in the future. Instead of more great observatories, we are looking toward a new vision encompassing a level of great activity through small, frequent missions. The strategy developed for attaining this vision was to lower costs by reducing size and complexity through new technology, while at the same time making progress in space science. The strategy comprises two interwoven parts: the flight program strategy of each of the science disciplines and OSSA's new-technology strategy. The overall purpose of all OSSA's efforts to date has been to free resources for maximizing the space science program in a tough fiscal environment.

  11. Strategies for Success

    ERIC Educational Resources Information Center

    Training, 2012

    2012-01-01

    "Training" magazine taps 2012 Training Top 125 winners and Top 10 Hall of Famers to provide their learning and development best practices in each issue. In this article, Jamie Leitch (American Infrastructure) and Mary Beth Alexander (The Economical Insurance Group) share strategies for tuition reimbursement and professional designations.

  12. Strategies for Success

    ERIC Educational Resources Information Center

    Pruitt, Lisa; McGeough, David

    2011-01-01

    "Training" magazine taps 2011 Training Top 125 winners to provide their learning and development best practices in each issue. This article looks at strategies for aligning training with business goals and creating models to measure return-on-investment (ROI) and other financial metrics pertaining to training.

  13. Strategy use and strategy choice in fraction magnitude comparison.

    PubMed

    Fazio, Lisa K; DeWolf, Melissa; Siegler, Robert S

    2016-01-01

    We examined, on a trial-by-trial basis, fraction magnitude comparison strategies of adults with more and less mathematical knowledge. College students with high mathematical proficiency used a large variety of strategies that were well tailored to the characteristics of the problems and that were guaranteed to yield correct performance if executed correctly. Students with less mathematical proficiency sometimes used strategies similar to those of the mathematically proficient students, but often used flawed strategies that yielded inaccurate performance. As predicted by overlapping waves theory, increases in accuracy and speed were related to differences in strategy use, strategy choice, and strategy execution. When asked to choose the best strategy from among 3 possibilities-the strategy the student originally used, a correct alternative, and an incorrect alternative-students with lower fraction knowledge rarely switched from an original incorrect strategy to a correct alternative. This finding suggests that use of poor fraction magnitude comparison strategies stems in large part from lack of conceptual understanding of the requirements of effective strategies, rather than difficulty recalling or generating such strategies. (PsycINFO Database Record

  14. Children's workforce strategy.

    PubMed

    2005-08-01

    The Green Paper, Every child matters, recognised the crucial importance of the children's workforce to improving outcomes for children and young people. The Children's Workforce Strategy sets out the government's vision of a world-class children's workforce which is increasingly competent and confident, inspiring trust and respect from parents and carers as well as from children and young people themselves. The document sets out four major strategic challenges: to recruit more high quality staff into the children's workforce; to retain people in the workforce including by offering better development and career progression; to strengthen interagency and multi-disciplinary working; and to promote stronger leadership and management. The strategy builds on work already in hand and on existing good practice. It puts forward proposals to tackle each of the strategic challenges with action nationally and locally.

  15. [Ventilatory strategy for ARDS].

    PubMed

    Yoshida, Takeshi; Takegawa, Ryousuke; Ogura, Hiroshi

    2016-02-01

    Fifteen years have passed since lung protective strategy to the patients with acute respiratory distress syndrome (ARDS) established. Recently, the new Berlin Definition of ARDS has been developed and this classified ARDS into three stages (mild, moderate, and severe ARDS), depending on the PaO2/FiO2. After this new definition of ARDS, each treatment to the patients with ARDS should be considered, depending on the severity of lung injury, such as prone position to the patients with severe ARDS, muscle paralysis to the patients with severe ARDS. In this review article, we review the history of lung protective strategy and ARDS definition, discuss the novel physiological approaches to minimizing ventilator-induced lung injury, and highlight a numbers of experimental/clinical studies to support these concepts. PMID:26915253

  16. Prevention strategies for trichothecenes.

    PubMed

    Aldred, David; Magan, Naresh

    2004-10-10

    Contamination of cereal commodities with mycotoxins represents a significant hazard to consumer health and has thus received increasing attention from food safety authorities and legislators. For trichothecenes, and deoxynivalenol (DON) in particular, the imminent implementation of legislative limits has focused attention on ways to prevent entry of such mycotoxin contaminants into the food and feed chains. Knowledge of the pre- and post-harvest stages in the cereal production chain and in particular information on where prevention strategies can be implemented is being used to develop quality assurance systems for improving food safety. Information on the ecology of Fusarium species, breeding for resistance, more effective fungicides, potential for biological control and effective drying and storage and preservation systems, are all helping to develop effective preventative strategies for minimising consumer exposure to trichothecenes and other mycotoxins. PMID:15342093

  17. Children's word fluency strategies.

    PubMed

    Tallberg, I M; Carlsson, S; Lieberman, M

    2011-02-01

    Two word fluency tasks, the FAS letter fluency task and the "animal" semantic fluency task, were administered to 130 healthy Swedish-speaking children between 6 and 15 years of age. The main aim was to gather normative data on these word fluency tasks for Swedish-speaking children. Another purpose was to examine the switching and clustering strategies used, along with the occurrence of erroneous responses, in relation to demographic data and number of words retrieved. Both phonological and semantic analyses of switching and clustering were conducted. Higher age was found to be related to a more effective use of phonological and semantic switching and clustering strategies. The reference data resulting from this study may be of clinical value in examinations of children with various diagnoses, including language impairment.

  18. Biomaterial Strategies for Immunomodulation.

    PubMed

    Hotaling, Nathan A; Tang, Li; Irvine, Darrell J; Babensee, Julia E

    2015-01-01

    Strategies to enhance, suppress, or qualitatively shape the immune response are of importance for diverse biomedical applications, such as the development of new vaccines, treatments for autoimmune diseases and allergies, strategies for regenerative medicine, and immunotherapies for cancer. However, the intricate cellular and molecular signals regulating the immune system are major hurdles to predictably manipulating the immune response and developing safe and effective therapies. To meet this challenge, biomaterials are being developed that control how, where, and when immune cells are stimulated in vivo, and that can finely control their differentiation in vitro. We review recent advances in the field of biomaterials for immunomodulation, focusing particularly on designing biomaterials to provide controlled immunostimulation, targeting drugs and vaccines to lymphoid organs, and serving as scaffolds to organize immune cells and emulate lymphoid tissues. These ongoing efforts highlight the many ways in which biomaterials can be brought to bear to engineer the immune system.

  19. Retrievability Strategy Report

    SciTech Connect

    Gehner, P; Gilstrap, O J; Memory, R D; Wagner, R C

    1997-04-30

    Section 122 of the ''Nuclear Waste Policy Act'' requires that a repository be designed and constructed to permit retrieval of any spent fuel placed in such repository, during an appropriate period of operation of the facility, for one of these reasons: (1) to protect public health and safety, or the environment; and (2) to permit the recovery of the economically valuable contents of such spent fuel. The Act also requires the Secretary to specify an appropriate period of retrievability at the time of the design of a repository. The Secretary has not yet defined any such period. However, the Nuclear Regulatory Commission, in the Code of Federal Regulations Title 10 Part 60.111, requires the design of a geologic repository operations area to allow the retrieval of any or all waste on a reasonable schedule starting at any time up to 50 years after waste operations are initiated. NRC describes a reasonable schedule as one that would permit retrieval in about the same time as it took to construct the repository and emplace the waste. Based on the existing conceptual repository and waste package design and analysis, the Yucca Mountain Project described retrieval operations under normal and abnormal conditions in the 1988 ''Site Characterization Plan (SCP)'' document. In 1991, under the same design assumptions, the Project issued a ''Retrieval Strategy Report for a Potential High-Level Nuclear Waste Repository''. Both the conceptual design of the waste package and the emplacement methods have since changed significantly. This report presents the results of a study to determine whether and to what degree these design and other changes require a revision of the retrieval strategy and, if they do, to recommend a revised strategy. The aim of such a revised strategy was to inform decision makers on how to proceed with design to allow retrievability.

  20. The strategy of cramming.

    SciTech Connect

    Wos, L.; Mathematics and Computer Science

    2003-01-01

    Offered in this article is a new strategy, cramming, that can serve well in an attempt to answer an open question or in an attempt to find a shorter proof. Indeed, when the question can be answered by proving a conjunction, cramming can provide substantial assistance. The basis of the strategy rests with forcing so many steps of a subproof into the remainder of the proof that the desired answer is obtained. As for reduction in proof length, the literature shows that proof shortening (proof abridgment) was indeed of interest to some of the masters of logic, masters that include C. A. Meredith, A. Prior, and I. Thomas. The problem of proof shortening (as well as other aspects of simplification) is also central to the recent discovery by R. Thiele of Hilbert's twenty-fourth problem. Although that problem was not included in his 1900 Paris lecture (because he had not yet sufficiently formulated it), Hilbert stressed at various times in his life the importance of finding simpler proofs. Because a sharp reduction in proof length (of constructive proofs) is correlated with a significant reduction in the complexity of the object being constructed, the cramming strategy is relevant to circuit design and program synthesis. The most impressive success with the use of the cramming strategy concerns an abridgment of the Meredith-Prior abridging of the ukasiewicz proof for his shortest single axiom for the implicational fragment of two-valued sentential (or classical propositional) calculus. In the context of answering open questions, the most satisfying examples to date concern the study of the right-group calculus and the study of the modal logic C5. Various challenges are offered here.

  1. Space Science Enterprise Strategy

    NASA Technical Reports Server (NTRS)

    2003-01-01

    The 2003 Space Science Enterprise Strategy represents the efforts of hundreds of scientists, staff, and educators, as well as collaboration with the other NASA Enterprises. It reveals the progress we have made, our plans for the near future, and our opportunity to support the Agency's Mission to "explore the universe and search for life." Space science has made spectacular advances in the recent past, from the first baby pictures of the universe to the discovery of water ice on Mars. Each new discovery impels us to ask new questions or regard old ones in new ways. How did the universe begin? How did life arise? Are we alone? These questions continue to inspire all of us to keep exploring and searching. And, as we get closer to answers, we will continue to share our findings with the science community, educators, and the public as broadly and as rapidly as possible. In this Strategy, you will find science objectives that define NASA's quest for discovery. You will also find the framework of programs, such as flight missions and ground-based research, that will enable us to achieve these objectives. This Strategy is founded on recommendations from the community, as well as lessons learned from past programs, and maps the stepping-stones to the future of space science.

  2. Strategies for Estimating Discrete Quantities.

    ERIC Educational Resources Information Center

    Crites, Terry W.

    1993-01-01

    Describes the benchmark and decomposition-recomposition estimation strategies and presents five techniques to develop students' estimation ability. Suggests situations involving quantities of candy and popcorn in which the teacher can model those strategies for the students. (MDH)

  3. All strategy is local.

    PubMed

    Greenwald, Bruce; Kahn, Judd

    2005-09-01

    The aim of strategy is to master a market environment by understanding and anticipating the actions of other economic agents, especially competitors. A firm that has some sort of competitive advantage-privileged access to customers, for instance--will have relatively few competitors to contend with, since potential competitors without an advantage, if they have their wits about them, will stay away. Thus, competitive advantages are actually barriers to entry and vice versa. In markets that are exposed, by contrast, competition is intense. If the incumbents have even brief success in earning greater than normal returns on investments, new entrants will swarm in to grab a share of the profits. Sooner or later, the additional competition will push returns as far down as the firms' costs of capital. For firms operating in such markets, the only choice is to forget about strategy and run the business as efficiently as possible. Barriers to entry are easier to maintain in a competitive arena that is "local", either in the geographic sense or in the sense of being limited to one product or a handful of related ones. The two most powerful competitive advantages-customer captivity and economies of scale-are more achievable and sustainable in circumscribed markets of this kind. Their opposites are the open markets and host of rivals that are features of globalization. Compapies entering such markets risk frittering away the advantages they secured on smaller playing fields.., Ifa company wants to grow but still obtain superior returns, the authors argue, the best strategy is to dominate a series of discrete but preferably contiguous markets and then expand only at their edges. WalMart's diminishing margins over the past 15 years are strong evidence of the danger of proceeding otherwise. PMID:16171214

  4. Strategies for Teaching Astronomy

    NASA Astrophysics Data System (ADS)

    Bennett, J.

    2000-12-01

    No matter whether you are teaching school children, undergraduates, or colleagues, a few key strategies are always useful. I will present and give examples for the following five key strategies for teaching astronomy. 1. Provide a Contextual Framework: It is much easier to learn new facts or concepts if they can be ``binned" into some kind of pre-existing mental framework. Unless your listeners are already familiar with the basic ideas of modern astronomy (such as the hierarchy of structure in the universe, the scale of the universe, and the origin of the universe), you must provide this before going into the details of how we've developed this modern picture through history. 2. Create Conditions for Conceptual Change: Many people hold misconceptions about astronomical ideas. Therefore we cannot teach them the correct ideas unless we first help them unlearn their prior misconceptions. 3. Make the Material Relevant: It's human nature to be more interested in subjects that seem relevant to our lives. Therefore we must always show students the many connections between astronomy and their personal concerns, such as emphasizing how we are ``star stuff" (in the words of Carl Sagan), how studying other planets helps us understand our own, and so on. 4. Limit Use of Jargon: The number of new terms in many introductory astronomy books is larger than the number of words taught in many first courses in foreign language. This means the books are essentially teaching astronomy in a foreign language, which is a clear recipe for failure. We must find ways to replace jargon with plain language. 5. Challenge Your Students: Don't dumb your teaching down; by and large, students will rise to meet your expectations, as long as you follow the other strategies and practice good teaching.

  5. All strategy is local.

    PubMed

    Greenwald, Bruce; Kahn, Judd

    2005-09-01

    The aim of strategy is to master a market environment by understanding and anticipating the actions of other economic agents, especially competitors. A firm that has some sort of competitive advantage-privileged access to customers, for instance--will have relatively few competitors to contend with, since potential competitors without an advantage, if they have their wits about them, will stay away. Thus, competitive advantages are actually barriers to entry and vice versa. In markets that are exposed, by contrast, competition is intense. If the incumbents have even brief success in earning greater than normal returns on investments, new entrants will swarm in to grab a share of the profits. Sooner or later, the additional competition will push returns as far down as the firms' costs of capital. For firms operating in such markets, the only choice is to forget about strategy and run the business as efficiently as possible. Barriers to entry are easier to maintain in a competitive arena that is "local", either in the geographic sense or in the sense of being limited to one product or a handful of related ones. The two most powerful competitive advantages-customer captivity and economies of scale-are more achievable and sustainable in circumscribed markets of this kind. Their opposites are the open markets and host of rivals that are features of globalization. Compapies entering such markets risk frittering away the advantages they secured on smaller playing fields.., Ifa company wants to grow but still obtain superior returns, the authors argue, the best strategy is to dominate a series of discrete but preferably contiguous markets and then expand only at their edges. WalMart's diminishing margins over the past 15 years are strong evidence of the danger of proceeding otherwise.

  6. Strategy and the Internet.

    PubMed

    Porter, M E

    2001-03-01

    Many of the pioneers of Internet business, both dot-coms and established companies, have competed in ways that violate nearly every precept of good strategy. Rather than focus on profits, they have chased customers indiscriminately through discounting, channel incentives, and advertising. Rather than concentrate on delivering value that earns an attractive price from customers, they have pursued indirect revenues such as advertising and click-through fees. Rather than make trade-offs, they have rushed to offer every conceivable product or service. It did not have to be this way--and it does not have to be in the future. When it comes to reinforcing a distinctive strategy, Michael Porter argues, the Internet provides a better technological platform than previous generations of IT. Gaining competitive advantage does not require a radically new approach to business; it requires building on the proven principles of effective strategy. Porter argues that, contrary to recent thought, the Internet is not disruptive to most existing industries and established companies. It rarely nullifies important sources of competitive advantage in an industry; it often makes them even more valuable. And as all companies embrace Internet technology, the Internet itself will be neutralized as a source of advantage. Robust competitive advantages will arise instead from traditional strengths such as unique products, proprietary content, and distinctive physical activities. Internet technology may be able to fortify those advantages, but it is unlikely to supplant them. Porter debunks such Internet myths as first-mover advantage, the power of virtual companies, and the multiplying rewards of network effects. He disentangles the distorted signals from the marketplace, explains why the Internet complements rather than cannibalizes existing ways of doing business, and outlines strategic imperatives for dot-coms and traditional companies. PMID:11246925

  7. Strategy and the Internet.

    PubMed

    Porter, M E

    2001-03-01

    Many of the pioneers of Internet business, both dot-coms and established companies, have competed in ways that violate nearly every precept of good strategy. Rather than focus on profits, they have chased customers indiscriminately through discounting, channel incentives, and advertising. Rather than concentrate on delivering value that earns an attractive price from customers, they have pursued indirect revenues such as advertising and click-through fees. Rather than make trade-offs, they have rushed to offer every conceivable product or service. It did not have to be this way--and it does not have to be in the future. When it comes to reinforcing a distinctive strategy, Michael Porter argues, the Internet provides a better technological platform than previous generations of IT. Gaining competitive advantage does not require a radically new approach to business; it requires building on the proven principles of effective strategy. Porter argues that, contrary to recent thought, the Internet is not disruptive to most existing industries and established companies. It rarely nullifies important sources of competitive advantage in an industry; it often makes them even more valuable. And as all companies embrace Internet technology, the Internet itself will be neutralized as a source of advantage. Robust competitive advantages will arise instead from traditional strengths such as unique products, proprietary content, and distinctive physical activities. Internet technology may be able to fortify those advantages, but it is unlikely to supplant them. Porter debunks such Internet myths as first-mover advantage, the power of virtual companies, and the multiplying rewards of network effects. He disentangles the distorted signals from the marketplace, explains why the Internet complements rather than cannibalizes existing ways of doing business, and outlines strategic imperatives for dot-coms and traditional companies.

  8. Instructional Strategies: A Preliminary Taxonomy.

    ERIC Educational Resources Information Center

    Merrill, M. David; Wood, Norman D.

    This paper proposes that instruction consists of four relatively independent facets: learner aptitudes, content structure, delivery systems, and instructional strategies. The purpose of this paper is to develop a taxonomic vocabulary and a model for portraying instructional strategies. Instructional strategies are defined as sequences of two or…

  9. Operations Strategy with Paper Boats

    ERIC Educational Resources Information Center

    Sumukadas, Narendar

    2010-01-01

    When participants in introductory business courses encounter the term "operations strategy," it is not easy for them to appreciate what operations strategy is about, or how it fits with overall business strategy. This game breaks down highfalutin jargon into experiences that participants can readily relate to. While working in teams to make paper…

  10. Developing Local Lifelong Guidance Strategies.

    ERIC Educational Resources Information Center

    Watts, A. G.; Hawthorn, Ruth; Hoffbrand, Jill; Jackson, Heather; Spurling, Andrea

    1997-01-01

    Outlines the background, rationale, methodology, and outcomes of developing local lifelong guidance strategies in four geographic areas. Analyzes the main components of the strategies developed and addresses a number of issues relating to the process of strategy development. Explores implications for parallel work in other localities. (RJM)

  11. Using Multiple Bonding Strategies.

    PubMed

    Larson, Thomas D

    2015-01-01

    There are many ways to bond to tooth structure, some micro-mechanical some chemical, some a combination. Different dentin bonding materials have different bonding strengths to differently prepared surfaces, and because of differences in their nature, different areas of tooth structure present peculiar bonding challenges. This paper will review a variety of material types, elucidating their particular bonding strengths and commenting on improved bonding strategies to increase durability, strength, and favorable pulpal response. In this discussion, resin dentin bonding systems, glass ionomers, Gluma, resin cements, and newer combined products will br reviewed. PMID:26485903

  12. Strategies for safe injections.

    PubMed Central

    Battersby, A.; Feilden, R.; Stoeckel, P.; Da Silva, A.; Nelson, C.; Bass, A.

    1999-01-01

    In 1998, faced with growing international concern, WHO set out an approach for achieving injection safety that encompassed all elements from patients' expectations and doctors' prescribing habits to waste disposal. This article follows that lead and describes the implications of the approach for two injection technologies: sterilizable and disposable. It argues that focusing on any single technology diverts attention from the more fundamental need for health services to develop their own comprehensive strategies for safe injections. National health authorities will only be able to ensure that injections are administered safely if they take an approach that encompasses the whole system, and choose injection technologies that fit their circumstances. PMID:10680247

  13. INL Green Building Strategy

    SciTech Connect

    Jennifer Dalton

    2005-05-01

    Green buildings, also known as sustainable buildings, resource efficient buildings, and high performance buildings, are structures that minimize the impact on the environment by using less energy and water, reducing solid waste and pollutants, and limiting the depletion of natural resources. As Idaho National Laboratory (INL) becomes the nation’s premier nuclear energy research laboratory, the physical infrastructure will be established to help accomplish the mission. This infrastructure, particularly the buildings, should incorporate green design features in order to be environmentally responsible and reflect an image of progressiveness and innovation to the public and prospective employees. With this in mind, the recommendations described in this strategy are intended to form the INL foundation for green building standards. The recommendations in this strategy are broken down into three levels: Baseline Minimum, Leadership in Energy and Environmental Design (LEED)Certification, and Innovative. Baseline Minimum features should be included in all new occupied buildings no matter what the purpose or size. These features do not require significant research, design, or capital costs and yet they can reduce Operation and Maintenance (O&M) costs and produce more environmentally friendly buildings. LEED Certification features are more aggressive than the Baseline Minimums in that they require documentation, studies, and/or additional funding. Combined with the Baseline Minimums, many of the features in this level will need to be implemented to achieve the goal of LEED certification. LEED Silver certification should be the minimum goal for all new buildings (including office buildings, laboratories, cafeterias, and visitor centers) greater than 25,000 square feet or a total cost of $10 million. Innovative features can also contribute to LEED certification, but are less mainstream than those listed in the previous two levels. These features are identified as areas where

  14. Optimal GENCO bidding strategy

    NASA Astrophysics Data System (ADS)

    Gao, Feng

    Electricity industries worldwide are undergoing a period of profound upheaval. The conventional vertically integrated mechanism is being replaced by a competitive market environment. Generation companies have incentives to apply novel technologies to lower production costs, for example: Combined Cycle units. Economic dispatch with Combined Cycle units becomes a non-convex optimization problem, which is difficult if not impossible to solve by conventional methods. Several techniques are proposed here: Mixed Integer Linear Programming, a hybrid method, as well as Evolutionary Algorithms. Evolutionary Algorithms share a common mechanism, stochastic searching per generation. The stochastic property makes evolutionary algorithms robust and adaptive enough to solve a non-convex optimization problem. This research implements GA, EP, and PS algorithms for economic dispatch with Combined Cycle units, and makes a comparison with classical Mixed Integer Linear Programming. The electricity market equilibrium model not only helps Independent System Operator/Regulator analyze market performance and market power, but also provides Market Participants the ability to build optimal bidding strategies based on Microeconomics analysis. Supply Function Equilibrium (SFE) is attractive compared to traditional models. This research identifies a proper SFE model, which can be applied to a multiple period situation. The equilibrium condition using discrete time optimal control is then developed for fuel resource constraints. Finally, the research discusses the issues of multiple equilibria and mixed strategies, which are caused by the transmission network. Additionally, an advantage of the proposed model for merchant transmission planning is discussed. A market simulator is a valuable training and evaluation tool to assist sellers, buyers, and regulators to understand market performance and make better decisions. A traditional optimization model may not be enough to consider the distributed

  15. Strategies in managing asthma.

    PubMed Central

    Barker, A F

    1989-01-01

    The management of adult asthma involves a concerted effort to identify and remove or mollify inciting or triggering stimuli such as respiratory tract infections, gastric reflux, aspirin, beta-antagonists, and environmental agents; educate patients, using written treatment plans and pulmonary function monitoring; and properly use the antiasthmatic medications including beta-agonists, theophylline, anticholinergics, and corticosteroids, with an emphasis on aerosol delivery and the use of corticosteroids during exacerbations. This strategy is summarized with suggestions on therapy in emergency departments, during the transition from hospital to ambulatory care, before exercise, and during pregnancy. PMID:2660411

  16. Natural hazards science strategy

    USGS Publications Warehouse

    Holmes, Jr., Robert R.; Jones, Lucile M.; Eidenshink, Jeffery C.; Godt, Jonathan W.; Kirby, Stephen H.; Love, Jeffrey J.; Neal, Christina A.; Plant, Nathaniel G.; Plunkett, Michael L.; Weaver, Craig S.; Wein, Anne; Perry, Suzanne C.

    2012-01-01

    The mission of the U.S. Geological Survey (USGS) in natural hazards is to develop and apply hazard science to help protect the safety, security, and economic well-being of the Nation. The costs and consequences of natural hazards can be enormous, and each year more people and infrastructure are at risk. USGS scientific research - founded on detailed observations and improved understanding of the responsible physical processes - can help to understand and reduce natural hazard risks and to make and effectively communicate reliable statements about hazard characteristics, such as frequency, magnitude, extent, onset, consequences, and where possible, the time of future events. To accomplish its broad hazard mission, the USGS maintains an expert workforce of scientists and technicians in the earth sciences, hydrology, biology, geography, social and behavioral sciences, and other fields, and engages cooperatively with numerous agencies, research institutions, and organizations in the public and private sectors, across the Nation and around the world. The scientific expertise required to accomplish the USGS mission in natural hazards includes a wide range of disciplines that this report refers to, in aggregate, as hazard science. In October 2010, the Natural Hazards Science Strategy Planning Team (H-SSPT) was charged with developing a long-term (10-year) Science Strategy for the USGS mission in natural hazards. This report fulfills that charge, with a document hereinafter referred to as the Strategy, to provide scientific observations, analyses, and research that are critical for the Nation to become more resilient to natural hazards. Science provides the information that decisionmakers need to determine whether risk management activities are worthwhile. Moreover, as the agency with the perspective of geologic time, the USGS is uniquely positioned to extend the collective experience of society to prepare for events outside current memory. The USGS has critical statutory

  17. Avionics advanced development strategy

    NASA Technical Reports Server (NTRS)

    Dyer, D.

    1990-01-01

    Discussed here is the problem of how to put together an integrated, phased, and affordable avionics advanced development program that links and applies to operational, evolving, and developing programs/vehicles, as well as those in the planning phases. Collecting technology needs from individual programs/vehicles and proposed technology items from individual developers usually results in a mismatch and something that is unaffordable. A strategy to address this problem is outlined with task definitions which will lead to avionics advanced development items that will fit within an overall framework, prioritized to support budgeting, and support the scope of NASA space transportations needs.

  18. Using Multiple Bonding Strategies.

    PubMed

    Larson, Thomas D

    2015-01-01

    There are many ways to bond to tooth structure, some micro-mechanical some chemical, some a combination. Different dentin bonding materials have different bonding strengths to differently prepared surfaces, and because of differences in their nature, different areas of tooth structure present peculiar bonding challenges. This paper will review a variety of material types, elucidating their particular bonding strengths and commenting on improved bonding strategies to increase durability, strength, and favorable pulpal response. In this discussion, resin dentin bonding systems, glass ionomers, Gluma, resin cements, and newer combined products will br reviewed.

  19. CMS multicore scheduling strategy

    SciTech Connect

    Perez-Calero Yzquierdo, Antonio; Hernandez, Jose; Holzman, Burt; Majewski, Krista; McCrea, Alison

    2014-01-01

    In the next years, processor architectures based on much larger numbers of cores will be most likely the model to continue 'Moore's Law' style throughput gains. This not only results in many more jobs in parallel running the LHC Run 1 era monolithic applications, but also the memory requirements of these processes push the workernode architectures to the limit. One solution is parallelizing the application itself, through forking and memory sharing or through threaded frameworks. CMS is following all of these approaches and has a comprehensive strategy to schedule multicore jobs on the GRID based on the glideinWMS submission infrastructure. The main component of the scheduling strategy, a pilot-based model with dynamic partitioning of resources that allows the transition to multicore or whole-node scheduling without disallowing the use of single-core jobs, is described. This contribution also presents the experiences made with the proposed multicore scheduling schema and gives an outlook of further developments working towards the restart of the LHC in 2015.

  20. Patent protection strategies

    PubMed Central

    Gupta, Himanshu; Kumar, Suresh; Roy, Saroj Kumar; Gaud, R. S.

    2010-01-01

    It is widely recognized that the pharmaceutical industry faces serious financial challenges. Large numbers of blockbuster drugs are losing patent protection and going generic. The pipeline of new drugs is too sparse to fill the gap and generate a platform for future growth. Moreover, many of the new products are biologics with much narrower target patient populations and comparatively higher prices relative to traditional pharmaceuticals. So now the time has come for pharmaceutical scientists to have a better understanding of patent fundamentals. This need is illustrated by analyses of key scientific and legal issues that arose during recent patent infringement cases involving Prozac, Prilosec, and Buspar. Facing this scenario, the pharmaceutical industry has moved to accelerate drug development process and to adopt at the same time different strategies to extend the life time of the patent monopoly to provide the economic incentives and utilizing it for drug discovery and development. This review covers the need of patent protection and various strategies to extend the patent. PMID:21814422

  1. Searching strategies in Dictyostelium

    NASA Astrophysics Data System (ADS)

    Li, Liang; Cox, Edward

    2007-03-01

    Levy walks are known to be the best strategy for optimizing non-destructive search times, while an intermittent two-state searching process optimizes the destructive case. Here we ask about hunting strategy in Dictyostelium amoebae when they cannot know where their food is. We show that correlated random walks with two typical correlation time scales bias their search, improving the search outcome. Further analysis indicates that cell trajectories consist of runs and turns. Strikingly, amoebae remember the last turn, and have a strong turning preference away from the last turn. Autocorrelation analysis of turn sequences indicates that this tendency does not persist beyond the nth+1 turn. Computer simulations reveal that this bias contributes to the longer of the two correlation times. The search rules are essentially the same when cells are continuously stimulated by cAMP, with different persistence times and lengths. Interestingly, new pseudopods form in an orientation opposite to the following turn. One of the correlation timescales is approximately 30 seconds in all cases, thus indicating a short-lived cellular process, while the other is 9 to 15 minutes suggesting a process sensitive to external signals, perhaps pseudopod extensions during turning.

  2. What's your lab's strategy?

    PubMed

    Francis, Peter

    2016-07-01

    Important strategic choices cascade throughout a laboratory. Senior management should create a document that answers each of the five key questions explained on page 60. Once this has been detailed in writing, it remains important to disseminate the basics to all employees so they are singing the same tune. A useful way to accomplish this is through a coherent strategy statement that specifies three components: 1) objectives; 2) scope; and 3) advantages. Commercial and hospital outreach labs should be in business to win. It all starts with a definition of what winning looks like. To "participate" in your market contributes to mediocrity-and it's self-defeating. With no clear strategic direction of where-to-play and how-to-win choices that associate with the aspiration, a mission or vision statement can be frustrating rather than inspiring for employees. Articulate it plainly and concisely for everybody. With a care-fully prepared and designed strategy, you will be on your way to winning in the zero-sum game! PMID:27548928

  3. CMS multicore scheduling strategy

    NASA Astrophysics Data System (ADS)

    Pérez-Calero Yzquierdo, Antonio; Hernández, Jose; Holzman, Burt; Majewski, Krista; McCrea, Alison; Cms Collaboration

    2014-06-01

    In the next years, processor architectures based on much larger numbers of cores will be most likely the model to continue "Moore's Law" style throughput gains. This not only results in many more jobs in parallel running the LHC Run 1 era monolithic applications, but also the memory requirements of these processes push the workernode architectures to the limit. One solution is parallelizing the application itself, through forking and memory sharing or through threaded frameworks. CMS is following all of these approaches and has a comprehensive strategy to schedule multicore jobs on the GRID based on the glideinWMS submission infrastructure. The main component of the scheduling strategy, a pilot-based model with dynamic partitioning of resources that allows the transition to multicore or whole-node scheduling without disallowing the use of single-core jobs, is described. This contribution also presents the experiences made with the proposed multicore scheduling schema and gives an outlook of further developments working towards the restart of the LHC in 2015.

  4. Gore proposes green strategy

    SciTech Connect

    1995-04-26

    A national environmental technology strategy laying out incentives for developing and using {open_quotes}green{close_quotes} technology was announced last week by Vice President Al Gore. The plan proposes a national goal of cutting waste 40%-50% and using 20%-25% less materials/unit of gross domestic product by Earth Day 2020. To meet that goal, the federal government aims to streamline environmental permitting, provide federal sites where US firms can test and demonstrate new technologies, create flexible regulation that encourages efficient and effective technologies, encourage research on pollution prevention, and improve monitoring data and information systems. The Administration says environmental technology is providing job growth twice that of the economy as a whole, and global markets are expected to rise from $300 billion to $500 billion by 2000. It adds that the US is the world market leader but only by a slim- and slipping-margin. Whereas previous federal support for environmental technologies focused on the front end of R&D and prototyping, the new strategy aims to bring technologies to market and encourage exports, according to the Administration`s National Commission for Employment Policy, which issued two reports last week. The commission says federal environmental policies now produce 68,000-80,000 jobs and contribute $3.5 billion-$3.7 billion to the economy.

  5. What's your lab's strategy?

    PubMed

    Francis, Peter

    2016-07-01

    Important strategic choices cascade throughout a laboratory. Senior management should create a document that answers each of the five key questions explained on page 60. Once this has been detailed in writing, it remains important to disseminate the basics to all employees so they are singing the same tune. A useful way to accomplish this is through a coherent strategy statement that specifies three components: 1) objectives; 2) scope; and 3) advantages. Commercial and hospital outreach labs should be in business to win. It all starts with a definition of what winning looks like. To "participate" in your market contributes to mediocrity-and it's self-defeating. With no clear strategic direction of where-to-play and how-to-win choices that associate with the aspiration, a mission or vision statement can be frustrating rather than inspiring for employees. Articulate it plainly and concisely for everybody. With a care-fully prepared and designed strategy, you will be on your way to winning in the zero-sum game!

  6. Mixed Strategies in cyclic competition

    NASA Astrophysics Data System (ADS)

    Intoy, Ben; Pleimling, Michel

    2015-03-01

    Physicists have been using evolutionary game theory to model and simulate cyclically competing species, with applications to lizard mating strategies and competing bacterial strains. However these models assume that each agent plays the same strategy, which is called a pure strategy in game theory, until they are beaten by a better strategy which they immediately adopt. We relax this constraint of an agent playing a single strategy by instead letting the agent pick its strategy randomly from a probability distribution, which is called a mixed strategy in game theory. This scheme is very similar to multiple occupancy models seen in the literature, the major difference being that interactions happen between sites rather than within them. Choosing strategies out of a distribution also has applications to economic/social systems such as the public goods game. We simulate a model of mixed strategy and cylic competition on a one-dimensional lattice with three and four strategies and find interesting spatial and stability properties depending on how discretized the choice of strategy is for the agents. This work is supported by the US National Science Foundation through Grant DMR-1205309.

  7. Dis-appearance and dys-appearance anew: living with excess skin and intestinal changes following weight loss surgery.

    PubMed

    Groven, Karen Synne; Råheim, Målfrid; Engelsrud, Gunn

    2013-08-01

    The aim of this article is to explore bodily changes following weight loss surgery. Our empirical material is based on individual interviews with 22 Norwegian women. To further analyze their experiences, we build primarily on the phenomenologist Drew Leder`s distinction between bodily dis-appearance and dys-appearance. Additionally, our analysis is inspired by Simone de Beauvoir, Merleau-Ponty and Julia Kristeva. Although these scholars have not directed their attention to obesity operations, they occupy a prime framework for shedding light on different dimensions of bodily change. In doing so, we were able to identify two main themes: The felt "inner" body versus the visible "surface" body and the "old" body versus the "new" body. In different, though interconnected ways, these main themes encompass tensions between changes the women experienced as contributing to a more "normal" and active life, feeling more accepted, and changes that generated ambivalence. In particular, their skin became increasingly problematic because it did not "shrink" like the rest of the body. On the contrary, it became looser and looser. Moreover, badsmelling folds of skin that wobbled, sweated and chafed at the smallest movement, aprons of fat hanging in front of their stomachs, batwing arms, thick flabby thighs and sagging breasts were described as a huge contrast to the positive response they received to their changed body shape when they were out and about with their clothes on. At the same time, they expressed ambivalence with regards to removing the excess skin by means of plastic surgery. Through their own and other women`s experiences they learned removing the excess skin by means of surgery could be a double-edged sword. By illuminating the experiences of the ones undergoing such changes our article offers new insight in a scholarly debate predominated by medical research documenting the positive outcomes of weight loss surgery.

  8. Seeing the World Anew: A Case Study of Ideas, Engagement, and Transfer in a 3 Year Old.

    ERIC Educational Resources Information Center

    Pugh, Kevin

    According to the philosophy of John Dewey, the goal of education is to provide students with an increased capacity for having worthwhile experiences. This paper draws on Dewey's writings to develop a theory of worthwhile experience, termed "idea-based experience." A model is proposed of how individuals are apprenticed into having an idea-based…

  9. The 'Jack Stone' or 'Mercedes Benz' sign--anew theory to explain the presence of gas within fissures in gallstones.

    PubMed

    Wright, F W

    1977-07-01

    Gas within clefts of fissures in gallstones is not a very common finding, but when it occurs is, characteristic and indicates the presence of one or more calculi. It closely resembles the appearance of a 'Jack Stone' but has previously been termed the 'Mercedes Benz' sign. Only a few cases have previously been recognised in the U.K. Most reported cases have been associated with biliary colic or cholecystitis. Various theories have been put forward to explain the presence of gas, but the author believes that the gas is released from solution by negative pressure within cholesterol stones undergoing internal fissuring due to their crystalline structure, i.e. the gas is released from solution from the small amount of fluid trapped in the calculus, in the same way that gas may be 'pulled' out of solution in a joint, a degenerate intervertebral disc or the fibro-cartilage of the symphysis pubis.

  10. To Begin the World Anew: Smart Grids and the Need for a Comprehensive U.S. Energy Policy

    SciTech Connect

    Foster, Nikolas AF

    2011-12-01

    The United States is in the midst of a monumental transformation of its electric power grid. Advances in information and communication technologies and grid measurement and control devices have initiated the transition toward a more resilient, sustainable and efficient future power grid. Deployment of these technologies is being driven by policies encouraging the shift to a greener grid, incorporating clean and low carbon energy; as well as rising consumer demand for smarter ways to use existing resources.

  11. Transplant Ethics: Let's Begin the Conversation Anew : A Critical Look at One Institute's Experience with Transplant Related Ethical Issues.

    PubMed

    Shafran, David; Smith, Martin L; Daly, Barbara J; Goldfarb, David

    2016-06-01

    Standardizing consultation processes is increasingly important as clinical ethics consultation (CEC) becomes more utilized in and vital to medical practice. Solid organ transplant represents a relatively nascent field replete with complex ethical issues that, while explored, have not been systematically classified. In this paper, we offer a proposed taxonomy that divides issues of resource allocation from viable solutions to the issue of organ shortage in transplant and then further distinguishes between policy and bedside level issues. We then identify all transplant related ethics consults performed at the Cleveland Clinic (CC) between 2008 and 2013 in order to identify how consultants conceptually framed their consultations by the domains they ascribe to the case. We code the CC domains to those in the Core Competencies for Healthcare Consultation Ethics in order to initiate a broader conversation regarding best practices in these highly complex cases. A discussion of the ethical issues underlying living donor and recipient related consults ensues. Finally, we suggest that the ethical domains prescribed in the Core Competencies provide a strong starting ground for a common intra-disciplinary language in the realm of formal CEC.

  12. The 'Jack Stone' or 'Mercedes Benz' sign--anew theory to explain the presence of gas within fissures in gallstones.

    PubMed

    Wright, F W

    1977-07-01

    Gas within clefts of fissures in gallstones is not a very common finding, but when it occurs is, characteristic and indicates the presence of one or more calculi. It closely resembles the appearance of a 'Jack Stone' but has previously been termed the 'Mercedes Benz' sign. Only a few cases have previously been recognised in the U.K. Most reported cases have been associated with biliary colic or cholecystitis. Various theories have been put forward to explain the presence of gas, but the author believes that the gas is released from solution by negative pressure within cholesterol stones undergoing internal fissuring due to their crystalline structure, i.e. the gas is released from solution from the small amount of fluid trapped in the calculus, in the same way that gas may be 'pulled' out of solution in a joint, a degenerate intervertebral disc or the fibro-cartilage of the symphysis pubis. PMID:872516

  13. [Other therapeutic strategies].

    PubMed

    Saba, Ghassen; Nieto, Isabel; Bation, Rémy; Allaïli, Najib; Bennabi, Djamila; Moliere, Fanny; Richieri, Raphaëlle; Holtzmann, Jérôme; Bubrovszky, Maxime; Camus, Vincent; Charpeaud, Thomas; Courtet, Philippe; Courvoisier, Pierre; Haesebaert, Frédéric; Doumy, Olivier; El-Hage, Wissam; Garnier, Marion; d'Amato, Thierry; Bougerol, Thierry; Lançon, Christophe; Haffen, Emmanuel; Llorca, Pierre-Michel; Vaiva, Guillaume; Bellivier, Frank; Leboyer, Marion; Aouizerate, Bruno

    2016-03-01

    Non-selective and irreversible MAOI have become as third or fourth-line strategy for the management of treatment-resistant depression. Non-selective and irreversible MAOI requires careful monitoring of drug interactions and dietary restrictions. Nutritional supplements such as omega-3 have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment. The glutamate antagonist ketamine has been found to produce beneficial effects in the management of treatment-resistant depression while administered alone. Dopamine and/or norepinephrine agonists, such as methylphenidate, modafinil or pramipexole, have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment. PMID:26995510

  14. Label fusion strategy selection.

    PubMed

    Robitaille, Nicolas; Duchesne, Simon

    2012-01-01

    Label fusion is used in medical image segmentation to combine several different labels of the same entity into a single discrete label, potentially more accurate, with respect to the exact, sought segmentation, than the best input element. Using simulated data, we compared three existing label fusion techniques-STAPLE, Voting, and Shape-Based Averaging (SBA)-and observed that none could be considered superior depending on the dissimilarity between the input elements. We thus developed an empirical, hybrid technique called SVS, which selects the most appropriate technique to apply based on this dissimilarity. We evaluated the label fusion strategies on two- and three-dimensional simulated data and showed that SVS is superior to any of the three existing methods examined. On real data, we used SVS to perform fusions of 10 segmentations of the hippocampus and amygdala in 78 subjects from the ICBM dataset. SVS selected SBA in almost all cases, which was the most appropriate method overall. PMID:22518113

  15. Strategies for joint appointments.

    PubMed

    Royle, J; Crooks, D L

    1985-01-01

    The structure and policies governing joint appointments discussed above, are developed primarily through cooperation and collaboration between nursing service and education institutions. The joint appointee participates in the process of negotiation of salary, benefits and role responsibilities and exploration of the implications of the appointment for personal career development. Implementation and maintenance of the appointment requires the collaborative efforts of the joint appointee with both contracting agencies. Factors influencing the functioning of joint appointees have been identified and strategies to facilitate functioning presented. The joint appointee must be independent in thought and action yet adaptable to work within the boundaries of two social systems with differing values and expectations. Nursing management, peers and students can provide the support needed to overcome the frustrations and to achieve the rewards inherent in successful implementation of an exciting and innovative role. PMID:3852805

  16. Anesthesiology and competitive strategy.

    PubMed

    Gross, Wendy L; Gold, Barbara

    2009-03-01

    Whether we like it or not, medicine is big business. The argument is sometimes made that standard management strategies from the business world do not apply to medicine because the economics and practice of medicine are unique--driven by science and rapid rates of change. But an exploding knowledge base, light-speed technological development, and ever-changing reimbursement schemes are not exclusive to medicine and health care. Some fundamental principles of finance, business management, and strategic development have evolved to deal with problems of rapid change. These principles do apply to modern medicine. The business side of anesthesia practice is off-putting to many clinicians. However, knowledge of the market forces at play can help enhance patient care, improve service, expand opportunities, and extend the perimeter of the discipline. The mission and current market position of anesthesiology practice are considered here. PMID:19361778

  17. Enrichment Strategies in Phosphoproteomics.

    PubMed

    Leitner, Alexander

    2016-01-01

    The comprehensive study of the phosphoproteome is heavily dependent on appropriate enrichment strategies that are most often, but not exclusively, carried out on the peptide level. In this chapter, I give an overview of the most widely used techniques. In addition to dedicated antibodies, phosphopeptides are enriched by their selective interaction with metals in the form of chelated metal ions or metal oxides. The negative charge of the phosphate group is also exploited in a variety of chromatographic fractionation methods that include different types of ion exchange chromatography, hydrophilic interaction chromatography (HILIC), and electrostatic repulsion HILIC (ERLIC) chromatography. Selected examples from the literature will demonstrate how a combination of these techniques with current high-performance mass spectrometry enables the identification of thousands of phosphorylation sites from various sample types. PMID:26584921

  18. [Other therapeutic strategies].

    PubMed

    Saba, Ghassen; Nieto, Isabel; Bation, Rémy; Allaïli, Najib; Bennabi, Djamila; Moliere, Fanny; Richieri, Raphaëlle; Holtzmann, Jérôme; Bubrovszky, Maxime; Camus, Vincent; Charpeaud, Thomas; Courtet, Philippe; Courvoisier, Pierre; Haesebaert, Frédéric; Doumy, Olivier; El-Hage, Wissam; Garnier, Marion; d'Amato, Thierry; Bougerol, Thierry; Lançon, Christophe; Haffen, Emmanuel; Llorca, Pierre-Michel; Vaiva, Guillaume; Bellivier, Frank; Leboyer, Marion; Aouizerate, Bruno

    2016-03-01

    Non-selective and irreversible MAOI have become as third or fourth-line strategy for the management of treatment-resistant depression. Non-selective and irreversible MAOI requires careful monitoring of drug interactions and dietary restrictions. Nutritional supplements such as omega-3 have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment. The glutamate antagonist ketamine has been found to produce beneficial effects in the management of treatment-resistant depression while administered alone. Dopamine and/or norepinephrine agonists, such as methylphenidate, modafinil or pramipexole, have been found to produce beneficial effects in the management of treatment-resistant depression when administered in combination with the ongoing antidepressant treatment.

  19. Three strategies for conservation

    NASA Technical Reports Server (NTRS)

    1975-01-01

    The three strategies considered as energy conservation oriented were given: national energy conservation, electrification, and diversification. The first one applies to the near term period (now-1985), the second one to the mid term (1985-2000), and the third one to the far term (2000- ). The rest of this section was focussed on the near term period. The following proposed actions were considered: (1) roll back the price of newly discovered oil, (2) force conversion of many power plants from gas and oil to coal, (3) freeze gasoline production for three years at 1972 levels, (4) mandate automobile mileage requirements, (5) require industry to improve energy efficiency, and (6) require manufacture of household appliances with greater efficiency. Each of these six actions was described and discussed in more detail.

  20. Cognition enhancement strategies.

    PubMed

    Bibb, James A; Mayford, Mark R; Tsien, Joe Z; Alberini, Cristina M

    2010-11-10

    Many mental disorders and neurodegenerative and neurodevelopmental diseases involve cognitive deficits. Remarkable advances and new technologies are providing a clearer picture of the molecular basis of cognition. In conjunction with an SFN2010 symposium, we provided here a brief overview of the molecular mechanisms of cognition, with emphasis on the development of treatments for cognitive disorders. Activity-dependent changes in gene expression and protein synthesis integrate with synapse selection to form memory circuits. A neuronal activity-dependent molecular tagging system that uses the gene expression program to record memory circuit formation represents one new tool to study cognition. Regulation of protein translation, protein degradation, cytoskeletal dynamics, extracellular matrix interactions, second messenger signaling, and neurotransmitter receptor trafficking and function are all components of synaptic remodeling essential for cognition. Selective targeting of specific effectors in these processes, such as NMDA receptors, may serve as an effective strategy to treat cognitive deficits.

  1. Diversity as strategy.

    PubMed

    Thomas, David A

    2004-09-01

    IBM's turnaround in the last decade is an impressive and well-documented business story. But behind that success is a less told people story, which explains how the corporation dramatically altered its already diverse composition and created millions of dollars in new business. By the time Lou Gerstner took the helm in 1993, IBM had a long history of progressive management when it came to civil rights and equal-opportunity employment. But Gerstner felt IBM wasn't taking full advantage of a diverse market for talent, nor was it maximizing the potential of its diverse customer and employee base. So in 1995, he launched a diversity task force initiative to uncover and understand differences among people within the organization and find ways to appeal to an even broader set of employees and customers. Gerstner established a task force for each of eight constituencies: Asians; blacks; the gay, lesbian, bisexual, transgendered community; Hispanics; white men; Native Americans; people with disabilities; and women. He asked the task forces to research four questions: What does your constituency need to feel welcome and valued at IBM? What can the corporation do, in partnership with your group, to maximize your constituency's productivity? What can the corporation do to influence your constituency's buying decisions so that IBM is seen as a preferred solution provider? And with which external organizations should IBM form relationships to better understand the needs of your constituency? The answers to these questions became the basis for IBM's diversity strategy. Thomas stresses that four factors are key to implementing any major change initiative: strong support from company leaders, an employee base that is fully engaged with the initiative, management practices that are integrated and aligned with the effort, and a strong and well-articulated business case for action. All four elements have helped IBM make diversity a key corporate strategy tied to real growth.

  2. Strategy as ecology.

    PubMed

    Iansiti, Marco; Levien, Roy

    2004-03-01

    Microsoft's and Wal-Mart's preeminence in modern business has been attributed to any number of factors--from the vision and drive of their founders to the companies' aggressive competitive practices. But the authors maintain that the success realized by these two very different companies is due only partly to the organizations themselves; a bigger factor is the success of the networks of companies with which Microsoft and Wal-Mart do business. Most companies today inhabit ecosystems--loose networks of suppliers, distributors, and outsourcers; makers of related products or services; providers of relevant technology; and other organizations that affect, and are affected by, the creation and delivery of a company's own offering. Despite being increasingly central to modern business, ecosystems are still poorly understood and even more poorly managed. The analogy between business networks and biological ecosystems can aid this understanding by vividly highlighting certain pivotal concepts. The moves that a company makes will, to varying degrees, affect the health of its business network, which in turn will ultimately affect the organization's performance--for ill as well as for good. Because a company, like an individual species in a biological ecosystem, ultimately shares its fate with the network as a whole, smart firms pursue strategies that will benefit everyone. So how can you promote the health and the stability of your own ecosystem, determine your place in it, and develop a strategy to match your role, thereby helping to ensure your company's well-being? It depends on your role--current and potential--within the network. Is your company a niche player, a keystone, or a dominator? The answer to this question may be different for different parts of your business. It may also change as your ecosystem changes. Knowing what to do requires understanding the ecosystem and your organization's role in it.

  3. Divestiture: strategy's missing link.

    PubMed

    Dranikoff, Lee; Koller, Tim; Schneider, Antoon

    2002-05-01

    Although most companies dedicate considerable time and attention to acquiring and creating businesses, few devote much effort to divestitures. But regularly divesting businesses--even good, healthy ones--ensures that remaining units reach their potential and that the overall company grows stronger. Drawing on extensive research into corporate performance over the last decade, McKinsey consultants Lee Dranikoff, Tim Koller, and Antoon Schneider show that an active divestiture strategy is essential to a corporation's long-term health and profitability. In particular, they say that companies that actively manage their businesses through acquisitions and divestitures create substantially more shareholder value than those that passively hold on to their businesses. Therefore, companies should avoid making divestitures only in response to pressure and instead make them part of a well-thought-out strategy. This article presents a five-step process for doing just that: prepare the organization, identify the best candidates for divestiture, execute the best deal, communicate the decision, and create new businesses. As the fifth step suggests, divestiture is not an end in itself. Rather, it is a means to a larger end: building a company that can grow and prosper over the long haul. Wise executives divest so that they can create new businesses and expand existing ones. All of the funds, management time, and support-function capacity that a divestiture frees up should therefore be reinvested in creating shareholder value. In some cases, this will mean returning money to shareholders. But more likely than not, it will mean investing in attractive growth opportunities. In companies as in the marketplace, creation and destruction go hand in hand; neither flourishes without the other.

  4. Supervisory Control Strategy Development

    SciTech Connect

    Gary D. Storrick; Bojan Petrovic

    2007-02-28

    Task 4 of this collaborative effort between ORNL, Brazil, and Westinghouse for the International Nuclear Energy Research Initiative entitled “Development of Advanced Instrumentation and Control for an Integrated Primary System Reactor” focused on the design of the hierarchical supervisory control for multiple-module units. The state of the IRIS plant design – specifically, the lack of a detailed secondary system design – made developing a detailed hierarchical control difficult at this time. However, other simultaneous and ongoing efforts have contributed to providing the needed information. This report summarizes the results achieved under Task 4 of this Financial Assistance Award. Section 1.2 describes the scope of this effort. Section 2 discusses the IRIS control functions. Next, it briefly reviews the current control concepts, and then reviews the maneuvering requirements for the IRIS plant. It closes by noting the benefits that automated sequences have in reducing operator workload. Section 3 examines reactor loading in the frequency domain to establish some guidelines for module operation, paying particular attention to strategies for using process steam for desalination and/or district heating. The final subsection discusses the implications for reactor control, and argues that using the envisioned percentage (up to 10%) of the NSSS thermal output for these purposes should not significantly affect the NSSS control strategies. Section 4 uses some very general economic assumptions to suggest how one should approach multi-module operation. It concludes that the well-known algorithms used for economic dispatching could be used to help manage a multi-unit IRIS site. Section 5 addresses the human performance factors of multi-module operation. Section 6 summarizes our conclusions.

  5. Strategy as ecology.

    PubMed

    Iansiti, Marco; Levien, Roy

    2004-03-01

    Microsoft's and Wal-Mart's preeminence in modern business has been attributed to any number of factors--from the vision and drive of their founders to the companies' aggressive competitive practices. But the authors maintain that the success realized by these two very different companies is due only partly to the organizations themselves; a bigger factor is the success of the networks of companies with which Microsoft and Wal-Mart do business. Most companies today inhabit ecosystems--loose networks of suppliers, distributors, and outsourcers; makers of related products or services; providers of relevant technology; and other organizations that affect, and are affected by, the creation and delivery of a company's own offering. Despite being increasingly central to modern business, ecosystems are still poorly understood and even more poorly managed. The analogy between business networks and biological ecosystems can aid this understanding by vividly highlighting certain pivotal concepts. The moves that a company makes will, to varying degrees, affect the health of its business network, which in turn will ultimately affect the organization's performance--for ill as well as for good. Because a company, like an individual species in a biological ecosystem, ultimately shares its fate with the network as a whole, smart firms pursue strategies that will benefit everyone. So how can you promote the health and the stability of your own ecosystem, determine your place in it, and develop a strategy to match your role, thereby helping to ensure your company's well-being? It depends on your role--current and potential--within the network. Is your company a niche player, a keystone, or a dominator? The answer to this question may be different for different parts of your business. It may also change as your ecosystem changes. Knowing what to do requires understanding the ecosystem and your organization's role in it. PMID:15029791

  6. The office of strategy management.

    PubMed

    Kaplan, Robert S; Norton, David P

    2005-10-01

    There is a disconnect in most companies between strategy formulation and strategy execution. On average, 95% of a company's employees are unaware of, or do not understand, its strategy. If employees are unaware of the strategy, they surely cannot help the organization implement it effectively. It doesn't have to be like this. For the past 15 years, the authors have studied companies that achieved performance breakthroughs by adopting the Balanced Scorecard and its associated tools to help them better communicate strategy to their employees and to guide and monitor the execution of that strategy. Some companies, of course, have achieved better, longer-lasting improvements than others. The organizations that have managed to sustain their strategic focus have typically established a new corporate-level unit to oversee all activities related to strategy: an office of strategy management (OS M). The OSM, in effect, acts as the CEO's chief of staff. It coordinates an array of tasks: communicating corporate strategy; ensuring that enterprise-level plans are translated into the plans of the various units and departments; executing strategic initiatives to deliver on the grand design; aligning employees' plans for competency development with strategic objectives; and testing and adapting the strategy to stay abreast of the competition. The OSM does not do all the work, but it facilitates the processes so that strategy is executed in an integrated fashion across the enterprise. Although the companies that Kaplan and Norton studied use the Balanced Scorecard as the framework for their strategy management systems, the authors say the lessons of the OSM are applicable even to companies that do not use it.

  7. The office of strategy management.

    PubMed

    Kaplan, Robert S; Norton, David P

    2005-10-01

    There is a disconnect in most companies between strategy formulation and strategy execution. On average, 95% of a company's employees are unaware of, or do not understand, its strategy. If employees are unaware of the strategy, they surely cannot help the organization implement it effectively. It doesn't have to be like this. For the past 15 years, the authors have studied companies that achieved performance breakthroughs by adopting the Balanced Scorecard and its associated tools to help them better communicate strategy to their employees and to guide and monitor the execution of that strategy. Some companies, of course, have achieved better, longer-lasting improvements than others. The organizations that have managed to sustain their strategic focus have typically established a new corporate-level unit to oversee all activities related to strategy: an office of strategy management (OS M). The OSM, in effect, acts as the CEO's chief of staff. It coordinates an array of tasks: communicating corporate strategy; ensuring that enterprise-level plans are translated into the plans of the various units and departments; executing strategic initiatives to deliver on the grand design; aligning employees' plans for competency development with strategic objectives; and testing and adapting the strategy to stay abreast of the competition. The OSM does not do all the work, but it facilitates the processes so that strategy is executed in an integrated fashion across the enterprise. Although the companies that Kaplan and Norton studied use the Balanced Scorecard as the framework for their strategy management systems, the authors say the lessons of the OSM are applicable even to companies that do not use it. PMID:16250626

  8. Leadership Strategies: Re-Conceptualising Strategy for Educational Leadership

    ERIC Educational Resources Information Center

    Eacott, Scott

    2011-01-01

    Strategy is a much debated concept in the field of educational leadership. This article draws on a variety of data from a larger research programme focused on reconceptualising strategy in the specific context of school leadership. Rather than offering a definitive voice, this article lays the foundations for further inquiry on the topic through a…

  9. Strategy Use and Strategy Choice in Fraction Magnitude Comparison

    ERIC Educational Resources Information Center

    Fazio, Lisa K.; DeWolf, Melissa; Siegler, Robert S.

    2016-01-01

    We examined, on a trial-by-trial basis, fraction magnitude comparison strategies of adults with more and less mathematical knowledge. College students with high mathematical proficiency used a large variety of strategies that were well tailored to the characteristics of the problems and that were guaranteed to yield correct performance if executed…

  10. [Feminist strategies 2].

    PubMed

    Gendron, C

    1993-06-01

    This article is the second in a two-part series promoting the use of feminist strategies in nursing. Part one--in last month's issue--identified some of the myths in nursing. It focused mainly on the traditional scientific research methods upon which nursing research is based. In part two, the author defines the feminist approach and attempts to demonstrate the way nurses can use this approach to focus nursing care on women's specific needs. This approach consists of recognizing the components of patriarchal ideology, its myths and the reality of women and men. Feminism has restored the credibility of intuition, good listening skills, compassion, commitment and tolerance. They were long believed to be "feminine" and passive. These qualities do not discredit the women who possess them--many of whom are nurses, rather, they add to their competence. How can feminist nursing knowledge shed light on the different factors specific to a woman's life? Menopause, nutrition and domestic violence are examples presented by the author to address this question. Once nurses increase their knowledge of these factors--that up until now were not identified as women's needs--they will be able to rely upon their own capabilities to develop new methods of data collection, communication skills and promotion of their own professionalism. Through these conclusions, the author praises the feminist movement.

  11. The Social Strategy Game

    PubMed Central

    Gurven, Michael; Kaplan, Hillard; Winking, Jeffrey

    2010-01-01

    This paper examines social determinants of resource competition among Tsimane Amerindian women of Bolivia. We introduce a semi-anonymous experiment (the Social Strategy Game) designed to simulate resource competition among women. Information concerning dyadic social relationships and demographic data were collected to identify variables influencing resource competition intensity, as measured by the number of beads one woman took from another. Relationship variables are used to test how the affiliative or competitive aspects of dyads affect the extent of prosociality in the game. Using a mixed-modeling procedure, we find that women compete with those with whom they are quarreling over accusations of meat theft, mate competition, and rumor spreading. They also compete with members of their social network and with those who were designated as cooperative helpers or as close kin. Women take fewer beads from desired friends, neighbors, and from those viewed as enemies. We interpret favoritism toward enemies as resulting from fear of retribution. Our results suggest that social relations among women are multifaceted and often cannot be simplified by exclusive focus on genetic relatedness, physical proximity, or reciprocity. We argue that a complex understanding of cooperation and competition among women may require important contextual information concerning relationship history in addition to typical features of resource ecology. PMID:20526460

  12. Marketing Strategy and Implementation

    SciTech Connect

    2010-05-31

    This report documents the marketing campaign that has been designed for middle and high school students in New Mexico to increase interest in participation in national security careers at the National Nuclear Security Administration. This marketing campaign builds on the research that was previously conducted, as well as the focus groups that were conducted. This work is a part of the National Nuclear Security Preparedness Project (NSPP) being performed under a Department of Energy (DOE) / National Nuclear Security Administration (NNSA) grant. Outcome analysis was performed to determine appropriate marketing strategies. The analysis was based upon focus groups with middle school and high school students, student interactions, and surveys completed by students to understand and gauge student interest in Science, Technology, Engineering, and Math (STEM) subjects, interest in careers at NNSA, future job considerations, and student desire to pursue post-secondary education. Further, through the focus groups, students were asked to attend a presentation on NNSA job opportunities and employee requirements. The feedback received from the students was utilized to develop the focus and components of the marketing campaign.

  13. Evaluating software testing strategies

    NASA Technical Reports Server (NTRS)

    Selby, R. W., Jr.; Basili, V. R.; Page, J.; Mcgarry, F. E.

    1984-01-01

    The strategies of code reading, functional testing, and structural testing are compared in three aspects of software testing: fault detection effectiveness, fault detection cost, and classes of faults detected. The major results are the following: (1) Code readers detected more faults than did those using the other techniques, while functional tester detected more faults than did structural testers; (2) Code readers had a higher fault detection rate than did those using the other methods, while there was no difference between functional testers and structural testers; (3) Subjects testing the abstract data type detected the most faults and had the highest fault detection rate, while individuals testing the database maintainer found the fewest faults and spent the most effort testing; (4) Subjects of intermediate and junior expertise were not different in number or percentage of faults found, fault detection rate, or fault detection effort; (5) subjects of advanced expertise found a greater number of faults than did the others, found a greater percentage of faults than did just those of junior expertise, and were not different from the others in either fault detection rate or effort; and (6) Code readers and functional testers both detected more omission faults and more control faults than did structural testers, while code readers detected more interface faults than did those using the other methods.

  14. Making strategy: learning by doing.

    PubMed

    Christensen, C M

    1997-01-01

    Companies find it difficult to change strategy for many reasons, but one stands out: strategic thinking is not a core managerial competence at most companies. Executives hone their capabilities by tackling problems over and over again. Changing strategy, however, is not usually a task that they face repeatedly. Once companies have found a strategy that works, they want to use it, not change it. Consequently, most managers do not develop a competence in strategic thinking. This Manager's Tool Kit presents a three-stage method executives can use to conceive and implement a creative and coherent strategy themselves. The first stage is to identify and map the driving forces that the company needs to address. The process of mapping provides strategy-making teams with visual representations of team members' assumptions, those pictures, in turn, enable managers to achieve consensus in determining the driving forces. Once a senior management team has formulated a new strategy, it must align the strategy with the company's resource-allocation process to make implementation possible. Senior management teams can translate their strategy into action by using aggregate project planning. And management teams that link strategy and innovation through that planning process will develop a competence in implementing strategic change. The author guides the reader through the three stages of strategy making by examining the case of a manufacturing company that was losing ground to competitors. After mapping the driving forces, the company's senior managers were able to devise a new strategy that allowed the business to maintain a competitive advantage in its industry.

  15. Space Station Freedom altitude strategy

    NASA Technical Reports Server (NTRS)

    Mcdonald, Brian M.; Teplitz, Scott B.

    1990-01-01

    The Space Station Freedom (SSF) altitude strategy provides guidelines and assumptions to determine an altitude profile for Freedom. The process for determining an altitude profile incorporates several factors such as where the Space Shuttle will rendezvous with the SSF, when reboosts must occur, and what atmospheric conditions exist causing decay. The altitude strategy has an influence on all areas of SSF development and mission planning. The altitude strategy directly affects the micro-gravity environment for experiments, propulsion and control system sizing, and Space Shuttle delivery manifests. Indirectly the altitude strategy influences almost every system and operation within the Space Station Program. Evolution of the SSF altitude strategy has been a very dynamic process over the past few years. Each altitude strategy in turn has emphasized a different consideration. Examples include a constant Space Shuttle rendezvous altitude for mission planning simplicity, or constant micro-gravity levels with its inherent emphasis on payloads, or lifetime altitudes to provide a safety buffer to loss of control conditions. Currently a new altitude strategy is in development. This altitude strategy will emphasize Space Shuttle delivery optimization. Since propellant is counted against Space Shuttle payload-to-orbit capacity, lowering the rendezvous altitude will not always increase the net payload-to-orbit, since more propellant would be required for reboost. This altitude strategy will also consider altitude biases to account for Space Shuttle launch slips and an unexpected worsening of atmospheric conditions. Safety concerns will define a lower operational altitude limit, while radiation levels will define upper altitude constraints. The evolution of past and current SSF altitude strategies and the development of a new altitude strategy which focuses on operational issues as opposed to design are discussed.

  16. Migration strategies of insects.

    PubMed

    Dingle, H

    1972-03-24

    Physiological and ecological results from a variety of species are consistent with what seem to be valid general statements concerning insect migration. These are as follows: (i)During migration locomotory functions are enhanced and vegetative functions such as feeding and reproduction are suppressed. (ii) Migration usually occurs prereproductively in the life of the adult insect (the oogenesis-flight syndrome). (iii)Since migrant individuals are usually prereproductive, their reproductive values, and hence colonizing abilities, are at or near maximum. (iv) Migrants usually reside in temporary habitats. (v)Migrants have a high potential for population increase, r, which is also advantageous for colonizers. (vi)Both the physiological and ecological parameters of migration are modifiable by environmental factors (that is, phenotypically modifiable)to suit the prevailing conditions. Taken together, these criteria establish a comprehensive theory and adumbrate the basic strategy for migrant insects. This basic strategy is modified to suit the ecological requirements of individual species. Comparative studies of these modifications are of considerable theoretical and practical interest, the more so since most economically important insects are migrants. No satisfactory general statements can as yet be made with respect to the genotype and migration. Certainly we expect colonizing populiations to possess genotypes favoring a high r, but genotypic variation in r depends on the heritabilities of life table statistics, and such measurements are yet to be made (10, 53). The fact that flight duration can be increased by appropriate selection in Oncopeltus fasciatus, and the demonstration of additive genetic variance for this trait in Lygaeus kalmii, suggest that heritability studies of migratory behavior would also be worth pursuing. Most interesting of course, will be possible genetic correlations between migration and life history parameters. Also, migration often

  17. Blue ocean strategy.

    PubMed

    Kim, W Chan; Mauborgne, Renée

    2004-10-01

    Despite a long-term decline in the circus industry, Cirque du Soleil profitably increased revenue 22-fold over the last ten years by reinventing the circus. Rather than competing within the confines of the existing industry or trying to steal customers from rivals, Cirque developed uncontested market space that made the competition irrelevant. Cirque created what the authors call a blue ocean, a previously unknown market space. In blue oceans, demand is created rather than fought over. There is ample opportunity for growth that is both profitable and rapid. In red oceans--that is, in all the industries already existing--companies compete by grabbing for a greater share of limited demand. As the market space gets more crowded, prospects for profits and growth decline. Products turn into commodities, and increasing competition turns the water bloody. There are two ways to create blue oceans. One is to launch completely new industries, as eBay did with online auctions. But it's much more common for a blue ocean to be created from within a red ocean when a company expands the boundaries of an existing industry. In studying more than 150 blue ocean creations in over 30 industries, the authors observed that the traditional units of strategic analysis--company and industry--are of limited use in explaining how and why blue oceans are created. The most appropriate unit of analysis is the strategic move, the set of managerial actions and decisions involved in making a major market-creating business offering. Creating blue oceans builds brands. So powerful is blue ocean strategy, in fact, that a blue ocean strategic move can create brand equity that lasts for decades. PMID:15559577

  18. Strategy as active waiting.

    PubMed

    Sull, Donald N

    2005-09-01

    Successful executives who cut their teeth in stable industries or in developed countries often stumble when they face more volatile markets. They falter, in part, because they assume they can gaze deep into the future and develop a long-term strategy that will confer a sustainable competitive advantage. But visibility into the future of volatile markets is sharply limited because so many different variables are in play. Factors such as technological innovation, customers' evolving needs, government policy, and changes in the capital markets interact with one another to create unexpected outcomes. Over the past six years, Donald Sull, an associate professor at London Business School, has led a research project examining some of the world's most volatile markets, from national markets like China and Brazil to industries like enterprise software, telecommunications, and airlines. One of the most striking findings from this research is the importance of taking action during comparative lulls in the storm. Huge business opportunities are relatively rare; they come along only once or twice in a decade. And, for the most part, companies can't manufacture those opportunities; changes in the external environment converge to make them happen. What managers can do is prepare for these golden opportunities by managing smart during the comparative calm of business as usual. During these periods of active waiting, leaders must probe the future and remain alert to anomalies that signal potential threats or opportunities; exercise restraint to preserve their war chests; and maintain discipline to keep the troops battle ready. When a golden opportunity or"sudden death"threat emerges, managers must have the courage to declare the main effort and concentrate resources to seize the moment.

  19. Blue ocean strategy.

    PubMed

    Kim, W Chan; Mauborgne, Renée

    2004-10-01

    Despite a long-term decline in the circus industry, Cirque du Soleil profitably increased revenue 22-fold over the last ten years by reinventing the circus. Rather than competing within the confines of the existing industry or trying to steal customers from rivals, Cirque developed uncontested market space that made the competition irrelevant. Cirque created what the authors call a blue ocean, a previously unknown market space. In blue oceans, demand is created rather than fought over. There is ample opportunity for growth that is both profitable and rapid. In red oceans--that is, in all the industries already existing--companies compete by grabbing for a greater share of limited demand. As the market space gets more crowded, prospects for profits and growth decline. Products turn into commodities, and increasing competition turns the water bloody. There are two ways to create blue oceans. One is to launch completely new industries, as eBay did with online auctions. But it's much more common for a blue ocean to be created from within a red ocean when a company expands the boundaries of an existing industry. In studying more than 150 blue ocean creations in over 30 industries, the authors observed that the traditional units of strategic analysis--company and industry--are of limited use in explaining how and why blue oceans are created. The most appropriate unit of analysis is the strategic move, the set of managerial actions and decisions involved in making a major market-creating business offering. Creating blue oceans builds brands. So powerful is blue ocean strategy, in fact, that a blue ocean strategic move can create brand equity that lasts for decades.

  20. Mapping your innovation strategy.

    PubMed

    Anthony, Scott D; Eyring, Matt; Gibson, Lib

    2006-05-01

    In the complex sport of American football, teams rely on playbooks as thick as the Manhattan phone directory. But when it comes to creating innovative growth businesses-which is at least as complicated as professional football--most companies have not developed detailed game plans. Indeed, many managers have concluded that a fog enshrouds the world of innovation, obscuring high-potential opportunities. The authors believe that companies can penetrate that fog by developing growth strategies based on disruptive innovations, as defined by Clayton Christensen. Such innovations conform to a pattern: They offer an entirely new solution; they perform adequately along traditional dimensions and much better along other dimensions that matter more to target customers; and they are not initially appealing to powerful incumbents. Companies can develop customized checklists, or playbooks, by combining this basic pattern with analysis of major innovations in their markets. The key early on is to focus not on detailed financial estimates--which will always guide companies toward the markets most hostile to disruptive innovations--but on how well the innovation fits the pattern of success. It's also crucial to encourage flexibility: Companies must be willing to kill projects that are going nowhere, exempt innovations from standard development processes, and avoid burdening project teams with extra financing, which can keep them heading in the wrong direction. Companies can create competitive advantage by becoming champions at defining the pattern of successful innovations and executing against it. But as that pattern becomes obvious--and others emerge-building a sustainable advantage on innovation competencies will again prove elusive.

  1. Marketing Strategy and Implementation

    SciTech Connect

    2010-09-30

    This report documents the preparation of materials for the marketing campaign that has been designed for middle and high school students in New Mexico to increase interest in participation in national security careers at the National Nuclear Security Administration. The materials and the marketing campaign build on the research that was previously completed, as well as the focus groups that were conducted. This work is a part of the National Nuclear Security Preparedness Project (NSPP). Previous research included outcome analysis to determine appropriate marketing strategies. The analysis was based upon focus groups with middle school and high school students, student interactions, and surveys completed by students to understand and gauge student interest in Science, Technology, Engineering, and Math (STEM) subjects, interest in careers at NNSA, future job considerations, and student desire to pursue post-secondary education. Further, through the focus groups, students were asked to attend a presentation on NNSA job opportunities and employee requirements. The feedback received from the students was utilized to develop the focus and components of a marketing campaign divided into DISCO (Discovering Intelligence and Security Career Opportunities) for the middle school age group and DISCO…..Your Way! for high school age groups. Both campaigns have an intertwined message that focuses on the education of students in the various national security career opportunities at NNSA using the STEM concepts and the notion that almost any career they can think of has a fit within NNSA. Further, a special emphasis has been placed on the importance of obtaining a national security clearance when working at NNSA and the steps that will need to be taken during middle school, high school, and college to be allowed this opportunity.

  2. Deterrence and nuclear strategy

    SciTech Connect

    Lodal, J.M.

    1980-01-01

    Mr. Lodal sees the social aspects of an effective deterrence policy as no less important than its technological aspects; further, programs and policies must be put in place that enhance social cohesion, that demonstrate the will to carry through on the strategy that we in the Western world subscribe to. It is the challenge of this political objective that most demands our attention. He feels that, if we are to remain secure, we must restore not only political cohesion to the Western alliance but a sensible political relationship between the United States and the Soviet Union as well. Such a relationship will of necessity provide for arms control. If we are able to maintain the arms control agreements reached to date, including the ABM treaty and SALT II, we will be a step ahead. It is to be hoped that the administration taking office in January of 1981 can restore order to our political relationships and avoid the necessity of a major defense program change such as the one suggested here. Unfortunately, the risk of this not happening is very real, according to Mr. Lodal. Therefore, the conceptualizing of concrete policies to improve our strategic nuclear posture becomes imperative. Adding limited defenses to our traditional doctrine is simply the best of a set of difficult choices. Such defenses would make our threatened use of battlefield nuclear weapons more credible, and they would restore a measure of extended deterrence; battlefield weapons could be used with the knowledge that only a massive Soviet attack would harm the US homeland. Thus, the defense would create a second firebreak in the ladder of escalation.

  3. Math Fact Strategies Research Project

    ERIC Educational Resources Information Center

    Boso, Annie

    2011-01-01

    An action research project was conducted in order to determine effective math fact strategies for first graders. The traditional way of teaching math facts included using timed tests and flashcards, with most students counting on their fingers or a number line. Six new research-based strategies were taught and analyzed to decide which methods…

  4. Mental Strategies for Peak Performance

    ERIC Educational Resources Information Center

    Wang, Jin

    2006-01-01

    A key to controlling competitive anxiety under pressure is to develop an effective attentional strategy to use before competition. This article: (1) examines the causes and psychological mechanics of pre-competitive anxiety; (2) provides athletes with an easily understandable mental strategy for practical use; and (3) provides coaches with…

  5. Environmental Strategies. Technical Assistance Packet.

    ERIC Educational Resources Information Center

    Join Together, Boston, MA.

    Families, schools, community organizations, and local practitioners have an important role to play in bringing about changes in the larger physical and psychosocial environment. The environmental strategies of policy, enforcement, education, communication, and collaboration can all have a significant impact. These environmental strategies for…

  6. Case Marking Strategies in Kope.

    ERIC Educational Resources Information Center

    Clifton, John

    Case marking strategies in Kope, a Papuan language of Papua New Guinea, are analyzed in light of previous claims that most Papuan languages have one strategy for marking core relations and another for marking peripheral relations. A brief grammatical overview illustrates how core and peripheral relations are marked in Kope, including nominal case…

  7. BLM Environmental Education National Strategy.

    ERIC Educational Resources Information Center

    Bureau of Land Management (Dept. of Interior), Washington, DC.

    This environmental education strategy was developed by a Bureau of Land Management (BLM) Washington Office Task Group in collaboration with staff at all levels of the BLM. The strategy calls for the BLM to expand its efforts in educating citizens about ecosystems and ecosystem management, and to establish environmental education as an integral…

  8. Instructional Strategies for Braille Literacy.

    ERIC Educational Resources Information Center

    Wormsley, Diane P., Ed.; D'Andrea, Frances Mary, Ed.

    This collection of readings is intended to provide teachers of children who are blind or visually impaired with guidelines and strategies for teaching the reading and writing of braille. The eight chapters are: (1) "Braille as the Primary Literacy Medium: General Guidelines and Strategies" (Diane P. Wormsley); (2) "Fostering Emergent Literacy"…

  9. Learning Strategy Instruction Innovation Configuration

    ERIC Educational Resources Information Center

    Schumaker, Jean B.

    2011-01-01

    One way of helping students with learning disabilities and other struggling students to be independent life-long learners is to teach them how to use learning strategies in efficient ways. Learning strategy instruction can provide students the opportunity to succeed in today's schools and meet rigorous standards, transforming ineffective learners…

  10. Successful Community College Election Strategies.

    ERIC Educational Resources Information Center

    King, D. Brian

    This study identifies successful election strategies employed by community colleges in bond issues or tax levy increase elections, and distills these strategies into a list of principles or rules that can be utilized by colleges in preparing for such an event. Results of case studies conducted at Maricopa (Arizona), Santa Monica (California), and…

  11. Improving Writing: Resources, Strategies, Assessments.

    ERIC Educational Resources Information Center

    Lenski, Susan Davis; Johns, Jerry L.

    Comprehensive and practical, this book provides resources, strategies, and assessments that seamlessly weave writing into everyday classroom routines. The resources in the book include reproducible student worksheets, transparency masters, teacher and student examples, and technology tips in the form of Web site addresses. Strategies throughout…

  12. National Drug Control Strategy. Update.

    ERIC Educational Resources Information Center

    Office of National Drug Control Policy, Washington, DC.

    President Bush's new National Drug Control Strategy for 2003 focuses on three core priorities: stopping drug use before it starts; healing America's drug users; and disrupting the market. The 2003 strategy reports progress toward meeting the President's goals of reducing drug use by 10 percent over 2 years, and 25 percent over 5 years. With regard…

  13. Strategy Notebook; Tools For Change.

    ERIC Educational Resources Information Center

    McEver, Catherine

    A detailed analysis of 76 major heuristic strategies or processes is provided in this supplementary text to the course, Tools for Change. Each strategy is conceptualized as a pair of active verbs which represent alternative, although not necessarily opposite, approaches to problem-solving. Some examples are: a) commit-defer; b) record-recall; c)…

  14. Leadership Strategies for Managing Conflict.

    ERIC Educational Resources Information Center

    Kormanski, Chuck

    1982-01-01

    Discusses the impact of conflict in small group development theory. Views conflict as a positive, normally occurring behavior and presents leadership strategies involving withdrawal, suppression, integration, compromise, and power. Examines situational contingencies and presents a rationale for strategy selection and intervention. (Author)

  15. National Drug Control Strategy, 2011

    ERIC Educational Resources Information Center

    Office of National Drug Control Policy, 2011

    2011-01-01

    In May of 2010, President Obama released the Administration's inaugural "National Drug Control Strategy". Based on the premise that drug use and its consequences pose a threat not just to public safety, but also to public health, the 2010 "Strategy" represented the first comprehensive rebalancing of Federal drug control policy in the nearly 40…

  16. Strategy Process in Higher Education

    ERIC Educational Resources Information Center

    Kettunen, Juha

    2010-01-01

    Higher education institutions educate those who are the most talented and best able to secure the future for the next generation. This study examines an efficient strategy process in higher education and emphasises the importance of sufficient dialogue during the process. The study describes the strategy process of the Turku University of Applied…

  17. Some Strategies for Environmental Remediation

    ERIC Educational Resources Information Center

    Peterson, Jerrold M.

    1975-01-01

    Analyzed are three strategies for reducing or eliminating environmental pollution: private market, legal, and effluent tax. Since private market solutions function well only with small numbers of parties and legal solutions oscillate too much, the author recommends effluent taxes. This strategy optimizes the abatement benefits and implementation…

  18. National Drug Control Strategy. Update

    ERIC Educational Resources Information Center

    Office of National Drug Control Policy, 2005

    2005-01-01

    The first National Drug Control Strategy set ambitious two and five-year performance based goals: (1) to lower the rate of drug use by 10 percent over 2 years among both youth and adults; and (2) to lower the rate by 25 percent over 5 years. The chapters in this updated version are keyed to the strategies three priorities: (1) Stopping Use Before…

  19. Students' Strategies for Exception Handling

    ERIC Educational Resources Information Center

    Rashkovits, Rami; Lavy, Ilana

    2011-01-01

    This study discusses and presents various strategies employed by novice programmers concerning exception handling. The main contributions of this paper are as follows: we provide an analysis tool to measure the level of assimilation of exception handling mechanism; we present and analyse strategies to handle exceptions; we present and analyse…

  20. Learning Strategies and Hypermedia Instruction.

    ERIC Educational Resources Information Center

    Hartley, Kendall

    2001-01-01

    Investigated the potential of incorporating learning strategy instruction into hypermedia learning materials in a high school computer class. Discusses results of a six-week intervention where the experimental group participated in learning strategy training in conjunction with hypermedia computer networking lessons and reports results of pre- and…

  1. Memory Strategies for College Students.

    ERIC Educational Resources Information Center

    Reetz, Linda J.

    Seven memory strategies that can be taught to college students with learning disabilities or students who have not learned essential study skills are described: the method of loci, pegwords, keywords, rote rehearsal, chaining, clustering, and first letter mnemonics. To help college faculty provide direct instruction in the memory strategies, the…

  2. Instructional Strategies to Facilitate Learning

    ERIC Educational Resources Information Center

    Lunenburg, Frederick C.; Irby, Beverly J.

    2011-01-01

    Teacher behavior research has shown that teacher behaviors, as well as specific teaching strategies, make a difference with regard to student achievement. Ten durable instructional strategies are discussed: set induction, stimulus variation, reinforcement, questioning, recognizing attending behavior, lecturing or direct instruction, planned…

  3. Individual Differences in Generalisation Strategies

    ERIC Educational Resources Information Center

    Crisp, Rebecca; Inglis, Matthew; Mason, John; Watson, Anne

    2012-01-01

    A common activity in school mathematics is to derive a function from a table of values. There are two general strategies one might adopt to determine the function f. First, one might try to determine a connection between a particular n and f(n), and then evaluate whether it holds for other values of n. An alternative strategy would be to look for…

  4. ALEGRA-HEDP validation strategy.

    SciTech Connect

    Garasi, Christopher Joseph; Mehlhorn, Thomas Alan; Trucano, Timothy Guy

    2006-01-01

    This report presents a initial validation strategy for specific SNL pulsed power program applications of the ALEGRA-HEDP radiation-magnetohydrodynamics computer code. The strategy is written to be (1) broadened and deepened with future evolution of particular specifications given in this version; (2) broadly applicable to computational capabilities other than ALEGRA-HEDP directed at the same pulsed power applications. The content and applicability of the document are highly constrained by the R&D thrust of the SNL pulsed power program. This means that the strategy has significant gaps, indicative of the flexibility required to respond to an ongoing experimental program that is heavily engaged in phenomena discovery.

  5. Spent nuclear fuel sampling strategy

    SciTech Connect

    Bergmann, D.W.

    1995-02-08

    This report proposes a strategy for sampling the spent nuclear fuel (SNF) stored in the 105-K Basins (105-K East and 105-K West). This strategy will support decisions concerning the path forward SNF disposition efforts in the following areas: (1) SNF isolation activities such as repackaging/overpacking to a newly constructed staging facility; (2) conditioning processes for fuel stabilization; and (3) interim storage options. This strategy was developed without following the Data Quality Objective (DQO) methodology. It is, however, intended to augment the SNF project DQOS. The SNF sampling is derived by evaluating the current storage condition of the SNF and the factors that effected SNF corrosion/degradation.

  6. Skin anti-aging strategies

    PubMed Central

    Ganceviciene, Ruta; Liakou, Aikaterini I.; Theodoridis, Athanasios; Makrantonaki, Evgenia; Zouboulis, Christos C.

    2012-01-01

    Skin aging is a complex biological process influenced by a combination of endogenous or intrinsic and exogenous or extrinsic factors. Because of the fact that skin health and beauty is considered one of the principal factors representing overall “well-being” and the perception of “health” in humans, several anti-aging strategies have been developed during the last years. It is the intention of this article to review the most important anti-aging strategies that dermatologists have nowadays in hand, including including preventive measurements, cosmetological strategies, topical and systemic therapeutic agents and invasive procedures. PMID:23467476

  7. Communication Strategies in the Written Medium

    ERIC Educational Resources Information Center

    Xhaferi, Brikena

    2012-01-01

    The field of second language acquisition has distinguished between two types of strategies: learning strategies and communication strategies. Learning strategies deal with the receptive domain of intake, memory, storage, and recall. Communication strategies pertain to the employment of verbal and nonverbal mechanisms for the productive…

  8. Demons, Dictionaries, and Spelling Strategies.

    ERIC Educational Resources Information Center

    Dodd, Anne Wescott

    1988-01-01

    Suggests that personal spelling dictionaries and spelling error analysis are strategies which will help students improve their spelling more than memorizing lists of unrelated words from spelling books. (MS)

  9. Prisons must develop dementia strategy.

    PubMed

    2016-08-01

    'The prison service badly needs a properly resourced national strategy for its rapidly growing population of older prisoners, to guide its staff in their management of age-related conditions, such as dementia'. PMID:27573969

  10. Interference of quantum market strategies

    NASA Astrophysics Data System (ADS)

    Piotrowski, Edward W.; Sładkowski, Jan; Syska, Jacek

    2003-02-01

    Recent development in quantum computation and quantum information theory allows to extend the scope of game theory for the quantum world. The paper is devoted to the analysis of interference of quantum strategies in quantum market games.

  11. Strategies for Success in Academe.

    ERIC Educational Resources Information Center

    Logan, Terry J.

    1989-01-01

    This article details some of the changes that have occurred in U.S. land-grant universities and colleges of agriculture, and the resulting issues and challenges facing faculty. Strategies for addressing these challenges are proposed. (Author/CW)

  12. Competitive Strategy in Continuing Education.

    ERIC Educational Resources Information Center

    Baden, Clifford

    1987-01-01

    Reviews strategic variables available to those planning continuing education marketing programs. Discusses generic competitive strategies: (1) overall cost leadership, (2) differentiation, and (3) specialization. Mentions several potential problems. (CH)

  13. Biofilms in wounds: management strategies.

    PubMed

    Rhoads, D D; Wolcott, R D; Percival, S L

    2008-11-01

    Biofilms probably induce a chronic and/or 'quiet' inflammation in the chronic wound and so delay healing. This paper reviews current strategies that can be used to suppress biofilms in chronic wounds until better options are available.

  14. Putting leadership back into strategy.

    PubMed

    Montgomery, Cynthia A

    2008-01-01

    In recent decades an infusion of economics has lent the study of strategy much needed theory and empirical evidence. Strategy consultants, armed with frameworks and techniques, have stepped forward to help managers analyze their industries and position their companies for strategic advantage. Strategy has come to be seen as an analytical problem to be solved. But, says Montgomery, the Timken Professor of Business Administration at Harvard Business School, the benefits of this rigorous approach have attendant costs: Strategy has become a competitive game plan, separate from the company's larger sense of purpose. The CEO's unique role as arbiter and steward of strategy has been eclipsed. And an overemphasis on sustainable competitive advantage has obscured the importance of making strategy a dynamic tool for guiding the company's development over time. For any company, intelligent guidance requires a clear sense of purpose, of what makes the organization truly distinctive. Purpose, Montgomery says, serves as both a constraint on activity and a guide to behavior. Creativity and insight are key to forging a compelling organizational purpose; analysis alone will never suffice. As the CEO--properly a company's chief strategist--translates purpose into practice, he or she must remain open to the possibility that the purpose itself may need to change. Lou Gerstner did this in the 1990s, when he decided that IBM would evolve to focus on applying technology rather than on inventing it. So did Steve Jobs, when he rescued Apple from a poorly performing strategy and expanded the company into attractive new businesses. Watching over strategy day in and day out is the CEO's greatest opportunity to shape the firm as well as outwit the competition.

  15. New strategies in O M

    SciTech Connect

    Seeley, R.S.

    1993-10-01

    Companies that provide operations and maintenance (O M) services to independent power plants are changing their strategies in response to increasing cost pressures on owners. O M contractors are fine-tuning their approaches in several ways. Global contracts, new controls, and computerization are some of their strategies they are using. With these new approaches O M contractors can improve their services and project owners bottom lines.

  16. Putting leadership back into strategy.

    PubMed

    Montgomery, Cynthia A

    2008-01-01

    In recent decades an infusion of economics has lent the study of strategy much needed theory and empirical evidence. Strategy consultants, armed with frameworks and techniques, have stepped forward to help managers analyze their industries and position their companies for strategic advantage. Strategy has come to be seen as an analytical problem to be solved. But, says Montgomery, the Timken Professor of Business Administration at Harvard Business School, the benefits of this rigorous approach have attendant costs: Strategy has become a competitive game plan, separate from the company's larger sense of purpose. The CEO's unique role as arbiter and steward of strategy has been eclipsed. And an overemphasis on sustainable competitive advantage has obscured the importance of making strategy a dynamic tool for guiding the company's development over time. For any company, intelligent guidance requires a clear sense of purpose, of what makes the organization truly distinctive. Purpose, Montgomery says, serves as both a constraint on activity and a guide to behavior. Creativity and insight are key to forging a compelling organizational purpose; analysis alone will never suffice. As the CEO--properly a company's chief strategist--translates purpose into practice, he or she must remain open to the possibility that the purpose itself may need to change. Lou Gerstner did this in the 1990s, when he decided that IBM would evolve to focus on applying technology rather than on inventing it. So did Steve Jobs, when he rescued Apple from a poorly performing strategy and expanded the company into attractive new businesses. Watching over strategy day in and day out is the CEO's greatest opportunity to shape the firm as well as outwit the competition. PMID:18271318

  17. Tax planning strategies for physicians.

    PubMed

    Pope, Thomas R; Schwartz, Richard W

    2002-07-01

    The development of tax reduction strategies is a critical aspect of both corporate and personal financial planning because taxes represent the largest annual expenditure for the majority of Americans. The categories of tax reduction strategies discussed include charitable-giving techniques, ways to maximize business deductions, shifting income to family members, education tax incentives, retirement planning, and small business tax considerations. One use for these tax savings is the enhancement of a corporation's capabilities to provide services to patients.

  18. Switching strategies to optimize search

    NASA Astrophysics Data System (ADS)

    Shlesinger, Michael F.

    2016-03-01

    Search strategies are explored when the search time is fixed, success is probabilistic and the estimate for success can diminish with time if there is not a successful result. Under the time constraint the problem is to find the optimal time to switch a search strategy or search location. Several variables are taken into account, including cost, gain, rate of success if a target is present and the probability that a target is present.

  19. Branch strategies - Modeling and optimization

    NASA Technical Reports Server (NTRS)

    Dubey, Pradeep K.; Flynn, Michael J.

    1991-01-01

    The authors provide a common platform for modeling different schemes for reducing the branch-delay penalty in pipelined processors as well as evaluating the associated increased instruction bandwidth. Their objective is twofold: to develop a model for different approaches to the branch problem and to help select an optimal strategy after taking into account additional i-traffic generated by branch strategies. The model presented provides a flexible tool for comparing different branch strategies in terms of the reduction it offers in average branch delay and also in terms of the associated cost of wasted instruction fetches. This additional criterion turns out to be a valuable consideration in choosing between two strategies that perform almost equally. More importantly, it provides a better insight into the expected overall system performance. Simple compiler-support-based low-implementation-cost strategies can be very effective under certain conditions. An active branch prediction scheme based on loop buffers can be as competitive as a branch-target-buffer based strategy.

  20. Hawaii Energy Strategy: Program guide

    SciTech Connect

    Not Available

    1992-09-01

    The Hawaii Energy Strategy program, or HES, is a set of seven projects which will produce an integrated energy strategy for the State of Hawaii. It will include a comprehensive energy vulnerability assessment with recommended courses of action to decrease Hawaii`s energy vulnerability and to better prepare for an effective response to any energy emergency or supply disruption. The seven projects are designed to increase understanding of Hawaii`s energy situation and to produce recommendations to achieve the State energy objectives of: Dependable, efficient, and economical state-wide energy systems capable of supporting the needs of the people, and increased energy self-sufficiency. The seven projects under the Hawaii Energy Strategy program include: Project 1: Develop Analytical Energy Forecasting Model for the State of Hawaii. Project 2: Fossil Energy Review and Analysis. Project 3: Renewable Energy Resource Assessment and Development Program. Project 4: Demand-Side Management Program. Project 5: Transportation Energy Strategy. Project 6: Energy Vulnerability Assessment Report and Contingency Planning. Project 7: Energy Strategy Integration and Evaluation System.

  1. A belief-based evolutionarily stable strategy.

    PubMed

    Deng, Xinyang; Wang, Zhen; Liu, Qi; Deng, Yong; Mahadevan, Sankaran

    2014-11-21

    As an equilibrium refinement of the Nash equilibrium, evolutionarily stable strategy (ESS) is a key concept in evolutionary game theory and has attracted growing interest. An ESS can be either a pure strategy or a mixed strategy. Even though the randomness is allowed in mixed strategy, the selection probability of pure strategy in a mixed strategy may fluctuate due to the impact of many factors. The fluctuation can lead to more uncertainty. In this paper, such uncertainty involved in mixed strategy has been further taken into consideration: a belief strategy is proposed in terms of Dempster-Shafer evidence theory. Furthermore, based on the proposed belief strategy, a belief-based ESS has been developed. The belief strategy and belief-based ESS can reduce to the mixed strategy and mixed ESS, which provide more realistic and powerful tools to describe interactions among agents.

  2. Public goods and metabolic strategies.

    PubMed

    Bachmann, Herwig; Bruggeman, Frank J; Molenaar, Douwe; Branco Dos Santos, Filipe; Teusink, Bas

    2016-06-01

    Microbial growth can be characterized by a limited set of macroscopic parameters such as growth rate, biomass yield and substrate affinity. Different culturing protocols for laboratory evolution have been developed to select mutant strains that have one specific macroscopic growth parameter improved. Some of those mutant strains display tradeoffs between growth parameters and changed metabolic strategies, for example, a shift from respiration to fermentation. Here we discuss recent studies suggesting that metabolic strategies and growth parameter tradeoffs originate from a common set of physicochemical and cellular constraints, associated with the allocation of intracellular resources over biosynthetic processes, mostly protein synthesis. This knowledge will give insight in ecological and biological concepts and can be used for metabolic and evolutionary engineering strategies.

  3. Novel therapeutic strategies for cardioprotection.

    PubMed

    Sluijter, Joost P G; Condorelli, Gianluigi; Davidson, Sean M; Engel, Felix B; Ferdinandy, Peter; Hausenloy, Derek J; Lecour, Sandrine; Madonna, Rosalinda; Ovize, Michel; Ruiz-Meana, Marisol; Schulz, Rainer; Van Laake, Linda W

    2014-10-01

    The morbidity and mortality from ischemic heart disease (IHD) remain significant worldwide. The treatment for acute myocardial infarction has improved over the past decades, including early reperfusion of occluded coronary arteries. Although it is essential to re-open the artery as soon as possible, paradoxically this leads to additional myocardial injury, called acute ischemia-reperfusion injury (IRI), for which currently no effective therapy is available. Therefore, novel therapeutic strategies are required to protect the heart from acute IRI in order to reduce myocardial infarction size, preserve cardiac function and improve clinical outcomes in patients with IHD. In this review article, we will first outline the pathophysiology of acute IRI and review promising therapeutic strategies for cardioprotection. These include novel aspects of mitochondrial function, epigenetics, circadian clocks, the immune system, microvesicles, growth factors, stem cell therapy and gene therapy. We discuss the therapeutic potential of these novel cardioprotective strategies in terms of pharmacological targeting and clinical application. PMID:24837132

  4. Ventilatory strategies in trauma patients

    PubMed Central

    Arora, Shubhangi; Singh, Preet Mohinder; Trikha, Anjan

    2014-01-01

    Lung injury in trauma patients can occur because of direct injury to lung or due to secondary effects of injury elsewhere for example fat embolism from a long bone fracture, or due to response to a systemic insult such as; acute respiratory distress syndrome (ARDS) secondary to sepsis or transfusion related lung injury. There are certain special situations like head injury where the primary culprit is not the lung, but the brain and the ventilator strategy is aimed at preserving the brain tissue and the respiratory system takes a second place. The present article aims to delineate the strategies addressing practical problems and challenges faced by intensivists dealing with trauma patients with or without healthy lungs. The lung protective strategies along with newer trends in ventilation are discussed. Ventilatory management for specific organ system trauma are highlighted and their physiological base is presented. PMID:24550626

  5. Winning Strategies in Congested Traffic

    NASA Astrophysics Data System (ADS)

    Járai-Szabó, Ferenc; Néda, Zoltán

    2012-09-01

    One-directional traffic on two-lanes is modeled in the framework of a spring-block type model. A fraction q of the cars are allowed to change lanes, following simple dynamical rules, while the other cars keep their initial lane. The advance of cars, starting from equivalent positions and following the two driving strategies is studied and compared. As a function of the parameter q the winning probability and the average gain in the advancement for the lane-changing strategy is computed. An interesting phase-transition like behavior is revealed and conclusions are drawn regarding the conditions when the lane changing strategy is the better option for the drivers.

  6. Novel therapeutic strategies for cardioprotection.

    PubMed

    Sluijter, Joost P G; Condorelli, Gianluigi; Davidson, Sean M; Engel, Felix B; Ferdinandy, Peter; Hausenloy, Derek J; Lecour, Sandrine; Madonna, Rosalinda; Ovize, Michel; Ruiz-Meana, Marisol; Schulz, Rainer; Van Laake, Linda W

    2014-10-01

    The morbidity and mortality from ischemic heart disease (IHD) remain significant worldwide. The treatment for acute myocardial infarction has improved over the past decades, including early reperfusion of occluded coronary arteries. Although it is essential to re-open the artery as soon as possible, paradoxically this leads to additional myocardial injury, called acute ischemia-reperfusion injury (IRI), for which currently no effective therapy is available. Therefore, novel therapeutic strategies are required to protect the heart from acute IRI in order to reduce myocardial infarction size, preserve cardiac function and improve clinical outcomes in patients with IHD. In this review article, we will first outline the pathophysiology of acute IRI and review promising therapeutic strategies for cardioprotection. These include novel aspects of mitochondrial function, epigenetics, circadian clocks, the immune system, microvesicles, growth factors, stem cell therapy and gene therapy. We discuss the therapeutic potential of these novel cardioprotective strategies in terms of pharmacological targeting and clinical application.

  7. Public goods and metabolic strategies.

    PubMed

    Bachmann, Herwig; Bruggeman, Frank J; Molenaar, Douwe; Branco Dos Santos, Filipe; Teusink, Bas

    2016-06-01

    Microbial growth can be characterized by a limited set of macroscopic parameters such as growth rate, biomass yield and substrate affinity. Different culturing protocols for laboratory evolution have been developed to select mutant strains that have one specific macroscopic growth parameter improved. Some of those mutant strains display tradeoffs between growth parameters and changed metabolic strategies, for example, a shift from respiration to fermentation. Here we discuss recent studies suggesting that metabolic strategies and growth parameter tradeoffs originate from a common set of physicochemical and cellular constraints, associated with the allocation of intracellular resources over biosynthetic processes, mostly protein synthesis. This knowledge will give insight in ecological and biological concepts and can be used for metabolic and evolutionary engineering strategies. PMID:27054480

  8. Cognitive strategies of university athletes.

    PubMed

    Madigan, R; Frey, R D; Matlock, T S

    1992-06-01

    Thirty-six college basketball players and skiers, both men and women, were interviewed about their use of cognitive processes to prepare themselves for competition. The interviews examined cognitive techniques for enhancing motor skills and developing competitive strategies. During the interviews the subjects engaged in some of their cognitive preparation strategies and then described the details of these experiences. All athletes reported that the use of cognitive strategies enhanced their performance. Their imagery was rich, detailed, and multisensory. An average of three sensory modalities were present in the imagery. Vision, kinesthesis, and touch were the most common sensory experiences reported, but audition, taste, and smell were also experienced by some athletes. Strong affective states, especially confidence and satisfaction, accompanied the imagery. Individual differences in the imagery used by the athletes were also found and may be related to individual differences in the athletes' cognitive styles.

  9. Regional strategies for global leadership.

    PubMed

    Ghemawat, Pankaj

    2005-12-01

    The leaders of such global powerhouses as GE, Wal-Mart, and Toyota seem to have grasped two crucial truths: First, far from becoming submerged by the rising tide of globalization, geographic and other regional distinctions may in fact be increasing in importance. Second, regionally focused strategies, used in conjunction with local and global initiatives, can significantly boost a company's performance. The business and economic data reveal a highly regionalized world. For example, trade within regions, rather than across them, drove the surge of international commerce in the second half of the twentieth century. Regionalization is also apparent in foreign direct investment, companies' international sales, and competition among the world's largest multinationals. Harvard Business School Professor Pankaj Ghemawat says that the most successful companies employ five types of regional strategies in addition to--or even instead of--global ones: home base, portfolio, hub, platform, and mandate. Some companies adopt the strategies in sequence, but the most nimble switch from one to another and combine approaches as their markets and businesses evolve. At Toyota, for example, exports from the home base continue to be substantial even as the company builds up an international manufacturing presence. And as Toyota achieves economies of scale and scope with a strong network of hubs, the company also pursues economies of specialization through interregional mandates. Embracing regional strategies requires flexibility and creativity. A company must decide what constitutes a region, choose the most appropriate strategies, and mesh those strategies with the organization's existing structures. In a world that is neither truly global nor truly local, finding ways of coordinating within and across regions can deliver a powerful competitive advantage. PMID:16334585

  10. Regional strategies for global leadership.

    PubMed

    Ghemawat, Pankaj

    2005-12-01

    The leaders of such global powerhouses as GE, Wal-Mart, and Toyota seem to have grasped two crucial truths: First, far from becoming submerged by the rising tide of globalization, geographic and other regional distinctions may in fact be increasing in importance. Second, regionally focused strategies, used in conjunction with local and global initiatives, can significantly boost a company's performance. The business and economic data reveal a highly regionalized world. For example, trade within regions, rather than across them, drove the surge of international commerce in the second half of the twentieth century. Regionalization is also apparent in foreign direct investment, companies' international sales, and competition among the world's largest multinationals. Harvard Business School Professor Pankaj Ghemawat says that the most successful companies employ five types of regional strategies in addition to--or even instead of--global ones: home base, portfolio, hub, platform, and mandate. Some companies adopt the strategies in sequence, but the most nimble switch from one to another and combine approaches as their markets and businesses evolve. At Toyota, for example, exports from the home base continue to be substantial even as the company builds up an international manufacturing presence. And as Toyota achieves economies of scale and scope with a strong network of hubs, the company also pursues economies of specialization through interregional mandates. Embracing regional strategies requires flexibility and creativity. A company must decide what constitutes a region, choose the most appropriate strategies, and mesh those strategies with the organization's existing structures. In a world that is neither truly global nor truly local, finding ways of coordinating within and across regions can deliver a powerful competitive advantage.

  11. Effective strategies for behavior change.

    PubMed

    Coleman, Mary Thoesen; Pasternak, Ryan H

    2012-06-01

    Strategies that are most effective in both prevention and management of chronic disease consider factors such as age, ethnicity, community, and technology. Most behavioral change strategies derive their components from application of the health belief model, the theory of reasoned action/theory of planned behavior, transtheoretical model, and social cognitive theory. Many tools such as the readiness ruler and personalized action plan form are available to assist health care teams to facilitate healthy behavior change. Primary care providers can support behavior changes by providing venues for peer interventions and family meetings and by making new partnerships with community organizations.

  12. Effective strategies for behavior change.

    PubMed

    Coleman, Mary Thoesen; Pasternak, Ryan H

    2012-06-01

    Strategies that are most effective in both prevention and management of chronic disease consider factors such as age, ethnicity, community, and technology. Most behavioral change strategies derive their components from application of the health belief model, the theory of reasoned action/theory of planned behavior, transtheoretical model, and social cognitive theory. Many tools such as the readiness ruler and personalized action plan form are available to assist health care teams to facilitate healthy behavior change. Primary care providers can support behavior changes by providing venues for peer interventions and family meetings and by making new partnerships with community organizations. PMID:22608867

  13. Implementation of Strategies in Continuing Education

    ERIC Educational Resources Information Center

    Kettunen, Juha

    2005-01-01

    Purpose--The purpose of this paper is to provide higher education institutions with strategies of continuing education and methods to communicate and implement these strategies. Design/methodology/approach--The balanced scorecard approach is used to implement the strategy. It translates the strategy into tangible objectives, measures and targets…

  14. E-Learning Strategy for Earning Learners

    ERIC Educational Resources Information Center

    Singaravelu, G.

    2011-01-01

    The study enlightens the effectiveness of e-learning strategy in learning English among the in-service teachers who are studying B.Ed in School of Distance Education, Bharathiar University, Coimbatore. E-learning strategy is a life long learning strategy for earning in-service teachers. It is a strategy of remaining in employment, which can be…

  15. Developing User Strategies in PVS: A Tutorial

    NASA Technical Reports Server (NTRS)

    Archer, Myla; diVito, Ben; Munoz, Cesar

    2003-01-01

    This tutorial provides an overview of the PVS strategy language, and explains how to define new PVS strategies and load them into PVS, and how to create a strategy package. It then discusses several useful techniques that can be used in developing user strategies, and provides examples that illustrate many of these techniques.

  16. Strategies of Second-Language Communication.

    ERIC Educational Resources Information Center

    Palmberg, Rolf

    1978-01-01

    The use of the term "strategy" in second language communication is discussed, and a typology of communication strategies is presented. Communication strategies are those systematic devices a second language learner uses in attempting to express precise meaning in the target language. Definitions of learning strategies and communication strategies…

  17. Homosexuality in Turkey: strategies for managing heterosexism.

    PubMed

    Bakacak, Ayça Gelgeç; Oktem, Pinar

    2014-01-01

    The goal of this study was to identify the strategies used by young homosexuals to manage their sexual minority status in Turkey. In-depth interviews were conducted with 15 self-identified homosexual university students. The data on the strategies employed by homosexuals suggested a categorization of these strategies into four interrelated areas: strategies employed in the process of self-acceptance; strategies to manage sexual stigma and prejudice; strategies specific to the coming-out process; and the strategies used while openly expressing their sexual identities.

  18. Query Evaluation: Strategies and Optimizations.

    ERIC Educational Resources Information Center

    Turtle, Howard; Flood, James

    1995-01-01

    Discusses two query evaluation strategies used in large text retrieval systems: (1) term-at-a-time; and (2) document-at-a-time. Describes optimization techniques that can reduce query evaluation costs. Presents simulation results that compare the performance of these optimization techniques when applied to natural language query evaluation. (JMV)

  19. Counselor Hypothesis-Testing Strategies.

    ERIC Educational Resources Information Center

    Strohmer, Douglas C.; Newman, Lisa J.

    1983-01-01

    Reports two experiments relevant to the questioning strategies counselors use in testing their hypotheses about clients. Results supported the idea that counselors are able to take a tentative hypothesis about a client and test its accuracy against additional independent, unbiased observations of the client. (LLL)

  20. Basic Interpreting Strategies for Parents.

    ERIC Educational Resources Information Center

    Luetke-Stahlman, Barbara

    1993-01-01

    Some deaf interpreting strategies are offered to parents of children who are deaf or hard of hearing. Parents are urged to utilize space in their interpreting, use name signs, utilize sight lines to distinguish characters in stories, use exaggerated signs to translate nursery rhymes, place themselves carefully at a public performance, and learn…

  1. A Strategy for Program Evaluation.

    ERIC Educational Resources Information Center

    Leinhardt, Gaea

    This paper proposes a strategy for in-house evaluations in the context of an educational research and development facility. The obstacles in conducting an evaluation of colleagues' programs are discussed; these fall into two categories. First, there is a set of problems that relate to conflicts inherent in judging the work of a colleague without…

  2. Classroom Strategies for Introductory Geology.

    ERIC Educational Resources Information Center

    Clemons, Joan

    1991-01-01

    The author describes her use of writing assignments, small-group discussions, note-taking strategies (learning logs), and professional simulations in an introductory geology course. The learning log process consists of note taking on one side of a divided page. After taking notes, students review the notes and record their questions, reactions,…

  3. Successful Strategies for Teaching & Learning.

    ERIC Educational Resources Information Center

    American Association of Community Colleges, Washington, DC. National Council of Instructional Administrators.

    Focusing on strategies for increasing student success in the community college, this monograph profiles winners of the National Council of Instructional Administrators (NCIA) exemplary program competition for 1994. First, background information on the competition is provided, indicating that it considers programs in three categories:…

  4. Strategies That Make Learning Last

    ERIC Educational Resources Information Center

    Willingham, Daniel T.

    2014-01-01

    Researchers have asked college students how they study, and the results show that most use four inefficient strategies that do not often work: (1) reading assigned chapter, trying to understand individual sentences as he goes but not necessarily ensuring he's got the overall gist; (2) marking what he takes to be important points with a…

  5. Reading Strategies and Hypertext Comprehension

    ERIC Educational Resources Information Center

    Salmeron, Ladislao, Canas, Jose J.; Kintsch, Walter; Fajardo, Immaculada

    2005-01-01

    The literature on assessing the cognitive processes involved in hypertext comprehension during the past 15 years has yielded contradictory results. In this article we explore a possible factor affecting this situation, mainly the fact that previous works did not control for the potential effects on comprehension of reading strategies in hypertext.…

  6. Rhetorical Strategy: A Dramatistic Interpretation.

    ERIC Educational Resources Information Center

    Cragan, John F.

    The focus of the dramatistic approach as a method of rhetorical criticism is the message rather than the speaker, audience, or situation. Using the approach developed by Ernest Bormann, the rhetorical critic examines man's symbolic reality and reacts to it by looking for strategies that are inherent in certain dramas. Conspiracy dramas are popular…

  7. A Generic Comprehension Instructional Strategy.

    ERIC Educational Resources Information Center

    Baumann, James F.

    1983-01-01

    Presents a practical strategy for teaching reading comprehension that is based on current research and consists of five steps: (1) introduction, (2) example, (3) direct instruction, (4) teacher-directed and (5) independent practice. Provides sample lessons for each step. (FL)

  8. Telestroke network business model strategies.

    PubMed

    Fanale, Christopher V; Demaerschalk, Bart M

    2012-10-01

    Our objective is to summarize the evidence that supports the reliability of telemedicine for diagnosis and efficacy in acute stroke treatment, identify strategies for funding the development of a telestroke network, and to present issues with respect to economic sustainability, cost effectiveness, and the status of reimbursement for telestroke.

  9. OBIS: Outdoor Biology Instructional Strategies.

    ERIC Educational Resources Information Center

    Donovan, Edward P.; Richmond, Robert F.

    The Outdoor Biology Instructional Strategies (OBIS) project began in 1972 to enable non-school youth groups (aged 10-15) to gain firsthand experiences in outdoor environments. This descriptive paper explains the program including its purpose and historical background. Specific objectives are to: (1) stimulate curiosity about local environments;…

  10. Outdoor Biology Instructional Strategies (OBIS)

    ERIC Educational Resources Information Center

    McCormack, Alan J.

    1974-01-01

    Provides an overview of the Outdoor Biology Instructional Strategies (OBIS) project. This program has as its rationale the idea that a basic understanding of ecosystems, populations, communities, food chains, and interactions of organisms with the environment is essential in making intelligent decisions about the environment. (PEB)

  11. Strategy Guideline. HVAC Equipment Sizing

    SciTech Connect

    Burdick, Arlan

    2012-02-01

    This guide describes the equipment selection of a split system air conditioner and furnace for an example house in Chicago, IL as well as a heat pump system for an example house in Orlando, FL. The required heating and cooling load information for the two example houses was developed in the Department of Energy Building America Strategy Guideline: Accurate Heating and Cooling Load Calculations.

  12. Strategies of School District Conflict.

    ERIC Educational Resources Information Center

    McGuire, Jean B.

    1984-01-01

    Focuses on conflict seen as the result of attempts to achieve desired outcomes in organizational "games." Conflict arises when conflictual behaviors are viewed as appropriate strategies to achieve goals. Data from two school districts are analyzed to examine the sources of conflict and to suggest means of conflict management. (Author/CS)

  13. Quantum strategies of quantum measurements

    NASA Astrophysics Data System (ADS)

    Li, Chuan-Feng; Zhang, Yong-Sheng; Huang, Yun-Feng; Guo, Guang-Can

    2001-03-01

    In the classical Monty Hall problem, one player can always win with probability 2/3. We generalize the problem to the quantum domain and show that a fair two-party zero-sum game can be carried out if the other player is permitted to adopt quantum measurement strategy.

  14. Quantum Strategies and Local Operations

    NASA Astrophysics Data System (ADS)

    Gutoski, Gus

    2010-02-01

    This thesis is divided into two parts. In Part I we introduce a new formalism for quantum strategies, which specify the actions of one party in any multi-party interaction involving the exchange of multiple quantum messages among the parties. This formalism associates with each strategy a single positive semidefinite operator acting only upon the tensor product of the input and output message spaces for the strategy. We establish three fundamental properties of this new representation for quantum strategies and we list several applications, including a quantum version of von Neumann's celebrated 1928 Min-Max Theorem for zero-sum games and an efficient algorithm for computing the value of such a game. In Part II we establish several properties of a class of quantum operations that can be implemented locally with shared quantum entanglement or classical randomness. In particular, we establish the existence of a ball of local operations with shared randomness lying within the space spanned by the no-signaling operations and centred at the completely noisy channel. The existence of this ball is employed to prove that the weak membership problem for local operations with shared entanglement is strongly NP-hard. We also provide characterizations of local operations in terms of linear functionals that are positive and "completely" positive on a certain cone of Hermitian operators, under a natural notion of complete positivity appropriate to that cone. We end the thesis with a discussion of the properties of no-signaling quantum operations.

  15. Reading Comprehension Strategy: Rainbow Dots

    ERIC Educational Resources Information Center

    Moore, Claire; Lo, Lusa

    2008-01-01

    An action research study was conducted using the Rainbow Dots strategy to evaluate its effectiveness on reading comprehension skills in a third-grade class with students both with and without a specific learning disability. Results of the study indicated that students' overall performances in reading comprehension have increased. Students also…

  16. Stage 2--Information Seeking Strategies

    ERIC Educational Resources Information Center

    Elsenberg, Michael B.

    2005-01-01

    A brief overview of one Big6 stage by Mike Eisenberg, followed by articles by two exemplary Big6 teachers, Barbara Jansen and Rob Darrow, offering practical uses of the Big6 in elementary and secondary situations is presented. The two-part nature of information seeking strategies that includes brainstorming and choosing is emphasized.

  17. Campus Networking Strategies: An Introduction.

    ERIC Educational Resources Information Center

    Roberts, Michael M.

    1988-01-01

    This article is adapted from the introduction to EDUCOM's forthcoming book, Campus Networking Strategies, which includes 10 case study chapters detailing academic experiences with computer networking. Topics discussed in the introduction include network issues for management, networking economics, engineering and telecommunications issues, and…

  18. STRATEGIES FOR SELF-EDUCATION.

    ERIC Educational Resources Information Center

    DILL, WILLIAM R.; AND OTHERS

    SEVENTY YOUNG MANAGERS, FACING THE CHALLENGE OF SELF EDUCATION, WERE QUESTIONED ON THEIR AGENDAS AND STRATEGIES FOR LEARNING, AND THEIR CHANCES FOR SUCCESS IN LEARNING. EXECUTIVES FOUND DIFFICULTY IN DESCRIBING AGENDAS BECAUSE THEY LACKED TIME, OR PRACTICE, OR A SENSE OF PERSONAL IDENTITY. MAIN PRESSURES FOR SELF EDUCATION WERE TO QUALIFY FOR…

  19. A strategy for company improvement.

    PubMed

    Howley, L

    2000-03-01

    Strategies based on the kaizen methodology are designed to continuously improve company performance without the need for large capital investments. This article looks at how one company used simple kaizen principles to its advantage, achieving 67% increase in productivity and 10% reduction in the standard cost of product.

  20. America 2000: An Education Strategy.

    ERIC Educational Resources Information Center

    Department of Education, Washington, DC.

    "America 2000" is a national strategy (not a federal program) designed to accomplish in nine years the six national education goals first articulated by the president and the state governors at the 1989 "Education Summit" in Charlottesville, Virginia. America 2000 is described as having four major "parts," and this booklet is organized around…

  1. Network strategies in election campaigns

    NASA Astrophysics Data System (ADS)

    Javarone, Marco Alberto

    2014-08-01

    This study considers a simple variation of the voter model with two competing parties. In particular, we represent the case of political elections, where people can choose to support one of the two candidates or to remain neutral. People operate within a social network and their opinions depend on those of the people with whom they interact. Therefore, they may change their opinions over time, which may mean supporting one particular candidate or none. Candidates attempt to gain people’s support by interacting with them, whether they are in the same social circle (i.e. neighbors) or not. In particular, candidates follow a strategy of interacting for a time with people they do not know (that is, people who are not their neighbors). Our analysis of the proposed model sought to establish which network strategies are the most effective for candidates to gain popular support. We found that the most suitable strategy depends on the topology of the social network. Finally, we investigated the role of charisma in these dynamics. Charisma is relevant in several social contexts, since charismatic people usually exercise a strong influence over others. Our results showed that candidates’ charisma is an important contributory factor to a successful network strategy in election campaigns.

  2. Strategies for Counseling Infertile Couples.

    ERIC Educational Resources Information Center

    Daniluk, Judith C.

    1991-01-01

    Presents specific intervention strategies that may serve to reinforce infertility experience as opportunity for personal and marital growth. Concludes through counseling clients may complete much of the emotional work required to reach a point of resolution and acceptance of their infertility. (Author/ABL)

  3. Strategies for Learning through Writing

    ERIC Educational Resources Information Center

    Lumpkin, Angela

    2014-01-01

    Students of all ages struggle with the multiple processes involved with writing, including planning, practice, and drafting multiple revisions. This article describes four structured writing assignments in an introductory college course, as well as eight specific strategies for helping students enhance their writing abilities.

  4. Children's Strategies on the Internet

    ERIC Educational Resources Information Center

    Dunkels, Elza

    2008-01-01

    This paper presents the results of an interview study of 104 12-year old children. The aim was to learn more about how children use the Internet, what they find negative on the Internet and what coping strategies they use. The media debate seems to display consensus regarding what threats the Internet poses to young people. However, this study…

  5. Intervention Strategies for Sexual Abuse.

    ERIC Educational Resources Information Center

    Rencken, Robert H.

    This book provides a framework for understanding the dimensions (scope, taxonomy, philosophy) and dynamics (individual, familial, and societal) of child sexual abuse. The major focus is on integrated intervention strategies for any professional who must work with incomplete information. Chapter 1 provides an overview of the problem of child sexual…

  6. Corporate Strategy an Evolutionary Review

    NASA Astrophysics Data System (ADS)

    Fellman, Philip V.

    As Richard Rumelt indicates in his book, "Fundamental Issues in Strategy: A Research Agenda", corporate strategy is a relatively recent discipline. While pioneers in the field like B.H. Liddell Hart and Bruce Henderson (later to found the Boston Consulting Group and creator of the famous BCG Growth-Share Matrix) began their research during the Second World War, the modern field of business strategy as an academic discipline, taught in schools and colleges of business emerged rather later. Rumelt provides an interesting chronicle in the introduction to his volume by noting that historically corporate strategy, even when taught as a capstone course, was not really an organized discipline. Typically, depending on the school's location and resources, the course would either be taught by the senior most professor in the department or by an outside lecturer from industry. The agenda tended to be very much instructor specific and idiosyncratic rather than drawing in any systematized fashion upon the subject matter of an organized discipline.

  7. Narrative as a Teaching Strategy

    ERIC Educational Resources Information Center

    Butcher, Susan E.

    2006-01-01

    Research shows that those who are incarcerated, as a whole, have come from difficult past environments. This leads to having a different way of learning than most others who have had successful educational experiences. Because of this, my research project focused on exploring storytelling/narrative, as a teaching strategy, and how it influences…

  8. National Drug Control Strategy, 2006

    ERIC Educational Resources Information Center

    The White House, 2006

    2006-01-01

    This report presents a summary of the Fiscal Year 2007 Budget for the National Drug Control Strategy within the three key priority areas; education and community action, treatment and intervention, and disruption in the illegal drug market. The first chapter, "Stopping Drug Use Before It Starts," outlines the Administration's work to prevent the…

  9. Strategies for Mentoring Pedagogical Knowledge

    ERIC Educational Resources Information Center

    Hudson, Peter

    2013-01-01

    Fundamental for mentoring a preservice teacher is the mentor's articulation of pedagogical knowledge, which in this research draws upon specific practices, viz.: planning, timetabling lessons, preparation, teaching strategies, content knowledge, problem solving, questioning, classroom management, implementation, assessment and viewpoints for…

  10. Strategy Choices of Potential Entrepreneurs

    ERIC Educational Resources Information Center

    Alstete, Jeffrey W.

    2014-01-01

    The author examined the written business plans of 380 students who completed courses in entrepreneurship and small business management over an 11-year period. An analysis categorized the plans into five generic competitive strategy types, and the results found that 58% chose a traditional, focused differentiation approach. A large portion (28%)…

  11. Bilingual Education: Issues and Strategies.

    ERIC Educational Resources Information Center

    Padilla, Amado M., Ed.; And Others

    This collection of 16 studies examines the wide variety of issues surrounding bilingual education and reviews program design, evaluation, and classroom strategies. The following chapters review the 20-year history of bilingual education and concomitant political issues: (1) "Bilingual Education: Issues and Perspectives" (A. M. Padilla); and (2)…

  12. New Strategies in Cancer Nanomedicine.

    PubMed

    Tong, Rong; Kohane, Daniel S

    2016-01-01

    We review recent progress in cancer nanomedicine, including stimulus-responsive drug delivery systems and nanoparticles responding to light for phototherapy or tumor imaging. In addition, several new strategies to improve the circulation of nanoparticles in vivo, tumor penetration, and tumor targeting are discussed. The application of nanomedicine in cancer immunology, a relatively new type of cancer therapy, is also highlighted.

  13. Caring as a Managerial Strategy

    ERIC Educational Resources Information Center

    Kroth, Michael; Keeler, Carolyn

    2009-01-01

    The purpose of this article is to broaden the discourse about caring as a managerial strategy by describing caring from three perspectives: nursing, education, and management. The authors suggest that current organizational models inadequately address the caring connection between manager and employee. Definitions of managerial caring and care…

  14. Novel optical strategies for biodetection

    NASA Astrophysics Data System (ADS)

    Sakamuri, Rama M.; Wolfenden, Mark S.; Anderson, Aaron S.; Swanson, Basil I.; Schmidt, Jurgen S.; Mukundan, Harshini

    2013-09-01

    Although bio-detection strategies have significantly evolved in the past decade, they still suffer from many disadvantages. For one, current approaches still require confirmation of pathogen viability by culture, which is the `gold-standard' method, and can take several days to result. Second, current methods typically target protein and nucleic acid signatures and cannot be applied to other biochemical categories of biomarkers (e.g.; lipidated sugars). Lipidated sugars (e.g.; lipopolysaccharide, lipoarabinomannan) are bacterial virulence factors that are significant to pathogenicity. Herein, we present two different optical strategies for biodetection to address these two limitations. We have exploited bacterial iron sequestration mechanisms to develop a simple, specific assay for the selective detection of viable bacteria, without the need for culture. We are currently working on the use of this technology for the differential detection of two different bacteria, using siderophores. Second, we have developed a novel strategy termed `membrane insertion' for the detection of amphiphilic biomarkers (e.g. lipidated glycans) that cannot be detected by conventional approaches. We have extended this technology to the detection of small molecule amphiphilic virulence factors, such as phenolic glycolipid-1 from leprosy, which could not be directly detected before. Together, these strategies address two critical limitations in current biodetection approaches. We are currently working on the optimization of these methods, and their extension to real-world clinical samples.

  15. User benefits and funding strategies

    NASA Technical Reports Server (NTRS)

    Beauchamp, N. A.

    1975-01-01

    A three-step, systematic method is described for selecting relevant and highly beneficial payloads for the Interim Upper Stage (IUS) that will be used with the space shuttle until the space tug becomes available. Viable cost-sharing strategies which would maximize the number of IUS payloads and the benefits obtainable under a limited NASA budget were also determined.

  16. Five Strategies for Detecting Intelligence

    NASA Astrophysics Data System (ADS)

    Tough, Allen

    If highly intelligent life has evolved elsewhere in our galaxy, how might scientists detect it? This paper compares eleven search strategies on three dimensions. Which strategies are most likely to detect extraterrestrial intelligence or technology? Which strategies, if successful, will likely contribute a wealth of knowledge? What is the current status of actual projects? In order to detect evidence of extraterrestrial intelligence or technology many light-years from Earth, astronomers can search for (1) radio signals, using various approaches, (2) laser or other optical signals, (3) other incoming signals, or (4) signs of an astroengineering project or Dyson sphere. Scientists could also (5) broadcast a radio message asking distant civilizations to respond. Additional strategies arise because any civilizations in our galaxy are probably much older than us and will therefore have technology far beyond ours. A technologically sophisticated civilization could likely send a small but super-smart probe to explore our solar system. An alien probe in our solar system, beyond the Moon, might be detected (6) by ongoing astronomy and space exploration, or (7) by a dedicated search for evidence of a probe or its byproducts. If a super-smart probe has reached Earth, it might be detected (8) by routine military and intelligence monitoring, (9) by an invitation to ETI on the World Wide Web, (10) by achieving peace or some other threshold that the probe requires before contact, or (11) by developing rigorous new research designs to study anomalous phenomena.

  17. Probiotics in transition: novel strategies.

    PubMed

    Gosálbez, Luis; Ramón, Daniel

    2015-04-01

    Regulations regarding health claims made for probiotics demand their proven effectiveness and limit the array of microbial species regarded as safe for live consumption. Novel strategies such as moving to postbiotics and genetically modified probiotics may be necessary to increase the effectiveness of microbial products.

  18. Literacy: Development and Teaching Strategies.

    ERIC Educational Resources Information Center

    Orme, Liz; Masson, Susan

    This paper seeks to provide teachers with a sampling of before, during, and after reading strategies that are appropriate for use in K-12 classrooms. The paper first discusses diagnostic assessment methods in the classroom and presents activities which provide samples of informal diagnostic assessment. It then outlines some "before reading"…

  19. Strategies for the 1990s.

    ERIC Educational Resources Information Center

    Chaffee, Ellen Earle

    1990-01-01

    Eight strategies are recommended to higher education in the 1990s including committing to improving quality; stressing customer service; increasing use of data and analysis in management; developing data on outcomes issues, processes, and behaviors; and working cooperatively with elementary and secondary education. (MLW)

  20. Strategy Choice in Sociocultural Context.

    ERIC Educational Resources Information Center

    Ellis, Shari

    1997-01-01

    Recent research has documented the variety of memory strategies children have in their repertoires at different ages and with different degrees of task experience. Of growing importance is understanding the processes by which children choose among available approaches. Evidence suggests that sociocultural influences shape individual repertoires of…

  1. Behavioral Strategies for Psychological Intervention.

    ERIC Educational Resources Information Center

    Iowa State Dept. of Public Instruction, Des Moines. Div. of Pupil Personnel Services.

    Ten papers contributed by school psychologists or university educators working with school psychology programs review psychological theory and research on behavioral strategies for psychological intervention. Following an overview on the effective use of behavior modification in the school, nine behavior change methods are examined in terms of…

  2. A strategy for recovery: Report of the HST Strategy Panel

    NASA Technical Reports Server (NTRS)

    Brown, R. A. (Editor); Ford, H. C. (Editor)

    1991-01-01

    The panel met to identify and assess strategies for recovering the Hubble Space Telescope (HST) capabilities degraded by a spherical aberration. The panels findings and recommendations to correct the problem with HST are given. The optical solution is a pair of mirrors for each science instrument field of view. The Corrective Optics Space Telescope Axial Replacement (COSTAR) is the proposed device to carry and deploy the corrective optics. A 1993 servicing mission is planned.

  3. Fission power: an evolutionary strategy.

    PubMed

    Feiveson, H A; von Hippel, F; Williams, R H

    1979-01-26

    Motivated by concerns about the difficulty of safeguarding the large flows of plutonium in a breeder reactor fuel cycle, we explore the resource and economic implications of a strategy in which there is no nuclear weapons-usable material in fresh reactor fuel. The strategy involves the deployment of already developed types of advanced converter reactors which, unlike the breeder, can be operated effectively on proliferation-resistant once-through fuel cycles. Advanced converter reactors could be much more uranium-efficient on once-through fuel cycles than current systems and therefore could compete economically with breeders up to very high uranium prices. If necessary, the uranium requirements of an advanced converter reactor system could be reduced much further with the recycling of isotopically denatured uranium, but any commitment to a closed fuel cycle would be unnecessary for many decades.

  4. Relapsed Hodgkin Lymphoma: Management Strategies

    PubMed Central

    Montanari, Francesca; Diefenbach, Catherine

    2016-01-01

    Although Hodgkin lymphoma (HL) is largely curable with first-line therapy, approximately one-third of patients will not have a complete response to frontline treatment or will subsequently relapse. Only 50 % of these patients will be effectively salvaged with conventional therapies. The prognosis is particularly poor for those patients with chemotherapy refractory disease, who are unable to obtain even transient disease control, and for patients who relapse following high dose chemotherapy and autologous stem cell transplant. In this review, we summarize the most recent updates on the management of patients with relapsed HL, the role of novel therapies such as brentuximab vedotin, and an overview of promising new agents currently under investigation. We also discuss the role of consolidation strategies such as high-dose chemotherapy and autologous stem cell transplant, and reduced-intensity allogeneic hematopoietic stem cell transplant, and the need for new strategies in the elderly patient population. PMID:24942298

  5. Sound Strategies for Hearing Restoration

    PubMed Central

    Géléoc, Gwenaëlle S.G.; Holt, Jeffrey R.

    2014-01-01

    Hearing loss is the most common sensory deficit in humans with some estimates suggesting up to 300 million affected individuals worldwide. Both environmental and genetic factors contribute to hearing loss and can cause death of sensory cells and neurons. Since these cells do not regenerate, the damage tends to accumulate leading to profound deafness. Several biological strategies to restore auditory function are currently under investigation. Due to the success of cochlear implants, which offer partial recovery of auditory function for some profoundly deaf patients, potential biological therapies must extend hearing restoration to include greater auditory acuity and larger patient populations. Here we review the latest gene, stem-cell, and molecular strategies for restoring auditory function in animal models and the prospects for translating these approaches into viable clinical therapies. PMID:24812404

  6. Strategy for tactical cellular connectivity

    NASA Astrophysics Data System (ADS)

    Carlson, Frederick R.

    2011-06-01

    This paper proposes a strategy to unify four disparate networks under an Internet Protocol (IP) umbrella. The first network is the Army Warfighter Information Network - Tactical (WIN-T) area common user system. The second network is an extension to the area common user system using the Mobile Ad Hoc Interoperability Networking Gateway (MAINGATE) system. The third network is the Worldwide Interoperability for Microwave Access (WiMax) based wireless access network and the forth network is the 802.11 WiFi Network. It is the intent of this paper to propose a skeletal wireless strategy that at its core will create everything over IP (EoIP) and "Everything over IEEE" ("EoIEEE") standards at the tactical level of the battlefield.

  7. Properties of heuristic search strategies

    NASA Technical Reports Server (NTRS)

    Vanderbrug, G. J.

    1973-01-01

    A directed graph is used to model the search space of a state space representation with single input operators, an AND/OR is used for problem reduction representations, and a theorem proving graph is used for state space representations with multiple input operators. These three graph models and heuristic strategies for searching them are surveyed. The completeness, admissibility, and optimality properties of search strategies which use the evaluation function f = (1 - omega)g = omega(h) are presented and interpreted using a representation of the search process in the plane. The use of multiple output operators to imply dependent successors, and thus obtain a formalism which includes all three types of representations, is discussed.

  8. Interplay of approximate planning strategies.

    PubMed

    Huys, Quentin J M; Lally, Níall; Faulkner, Paul; Eshel, Neir; Seifritz, Erich; Gershman, Samuel J; Dayan, Peter; Roiser, Jonathan P

    2015-03-10

    Humans routinely formulate plans in domains so complex that even the most powerful computers are taxed. To do so, they seem to avail themselves of many strategies and heuristics that efficiently simplify, approximate, and hierarchically decompose hard tasks into simpler subtasks. Theoretical and cognitive research has revealed several such strategies; however, little is known about their establishment, interaction, and efficiency. Here, we use model-based behavioral analysis to provide a detailed examination of the performance of human subjects in a moderately deep planning task. We find that subjects exploit the structure of the domain to establish subgoals in a way that achieves a nearly maximal reduction in the cost of computing values of choices, but then combine partial searches with greedy local steps to solve subtasks, and maladaptively prune the decision trees of subtasks in a reflexive manner upon encountering salient losses. Subjects come idiosyncratically to favor particular sequences of actions to achieve subgoals, creating novel complex actions or "options." PMID:25675480

  9. Optimal strategies for familial searching.

    PubMed

    Kruijver, Maarten; Meester, Ronald; Slooten, Klaas

    2014-11-01

    Familial searching is the process of finding potential relatives of the donor of a crime scene profile in a DNA database. Several authors have proposed strategies for generating candidate lists of potential relatives. This paper reviews four strategies and investigates theoretical properties as well as empirical behavior, using a comprehensive simulation study on mock databases. The effectiveness of a familial search is shown to highly depend on the case profile as well as on the tuning parameters. We give recommendations for proceeding in an optimal way and on how to choose tuning parameters both in general and on a case-by-case basis. Additionally we treat searching heterogeneous databases (not all profiles comprise the same loci) and composite searching for multiple types of kinship. An R-package for reproducing results in a particular case is released to help decision-making in familial searching.

  10. Sound strategies for hearing restoration.

    PubMed

    Géléoc, Gwenaëlle S G; Holt, Jeffrey R

    2014-05-01

    Hearing loss is the most common sensory deficit in humans, with some estimates suggesting up to 300 million affected individuals worldwide. Both environmental and genetic factors contribute to hearing loss and can cause death of sensory cells and neurons. Because these cells do not regenerate, the damage tends to accumulate, leading to profound deafness. Several biological strategies to restore auditory function are currently under investigation. Owing to the success of cochlear implants, which offer partial recovery of auditory function for some profoundly deaf patients, potential biological therapies must extend hearing restoration to include greater auditory acuity and larger patient populations. Here, we review the latest gene, stem-cell, and molecular strategies for restoring auditory function in animal models and the prospects for translating these approaches into viable clinical therapies. PMID:24812404

  11. Therapy strategies in psoriatic arthritis.

    PubMed

    Coates, Laura C

    2015-01-01

    Psoriatic arthritis (PsA) is a heterogeneous condition with a myriad of different clinical presentations. It commonly affects the skin and musculoskeletal system causing psoriasis, peripheral arthritis, axial arthritis, enthesitis and dactylitis. Many patients also have related conditions, such as those within the metabolic syndrome and associated spondyloarthritis (SpA) conditions including inflammatory bowel disease and uveitis. Any therapeutic strategy must be tailored to the individual patient, taking into account her/his complete clinical presentation and comorbidities. New treatment recommendations from the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) provide evidence based recommendations on effective therapies for the management of each different manifestation of PsA, and how treatment may be affected by comorbidities (1). However, the limited evidence comparing different treatment strategies in PsA is recognised as a limitation in these recommendations and further information is detailed below.

  12. Ergonomics contributions to company strategies.

    PubMed

    Dul, Jan; Neumann, W Patrick

    2009-07-01

    Managers usually associate ergonomics with occupational health and safety and related legislation, not with business performance. In many companies, these decision makers seem not to be positively motivated to apply ergonomics for reasons of improving health and safety. In order to strengthen the position of ergonomics and ergonomists in the business and management world, we discuss company strategies and business goals to which ergonomics could contribute. Conceptual models are presented and examples are given to illustrate: (1) the present situation in which ergonomics is not part of regular planning and control cycles in organizations to ensure business performance; and (2) the desired situation in which ergonomics is an integrated part of strategy formulation and implementation. In order to realize the desired situation, considerable changes must take place within the ergonomics research, education and practice community by moving from a health ergonomics paradigm to a business ergonomics paradigm, without losing the health and safety goals.

  13. Radon mapping strategies in Austria.

    PubMed

    Gruber, V; Ringer, W; Wurm, G; Friedmann, H

    2015-11-01

    According to current European and international recommendations (e.g. by IAEA, WHO and European Union), countries shall identify high radon areas. In Austria, this task was initiated already in the early 1990s, which yielded the first Austrian Radon Potential Map. This map is still in use, updated with recent indoor radon data in 2012. The map is based on radon gas measurements in randomly selected dwellings, normalised to a standard situation. To meet the current (legal) requirements, uncertainties in the existing Austrian radon map should be reduced. A new indoor radon survey with a different sampling strategy was started, and possible mapping methods are studied and tested. In this paper, the methodology for the existing map as well as the planned strategies to improve this map is discussed.

  14. Wellness strategies for smaller businesses.

    PubMed

    Neely, Marc

    2012-01-01

    While innovative smaller companies are implementing employee wellness programs, many smaller firms may point to a lack of resources, such as staffing and financial resources, to establish and sustain a wellness program. The uncertain economy and rising health care costs have caused many smaller businesses to focus on core business strategies to keep the doors open and the business going. However, innovative companies realize that building a culture of health is a long-term business strategy directly related to improving the bottom line. This article highlights one company's approach to wellness and the results of the company's programs. It also outlines the components of a successful wellness program and suggests practical implementation steps for smaller businesses.

  15. Managing incontinence: women's normalizing strategies.

    PubMed

    Skoner, M M; Haylor, M J

    1993-01-01

    Women's strategies for managing urinary incontinence were examined in a grounded-theory study. The women's basic social concern was dealing with incontinence in a manner that enabled them to feel normal. Feeling normal meant being able to do what they wanted to do and needed to do to have a normal life-style as they perceived it. This goal was accomplished by normalizing incontinence and its management. Normalization was achieved by directing its course through self-management, accounting for it in terms of personal history and life experiences, and delaying medical counsel. These strategies are described. The findings provide fresh insights about women's response to incontinence and their practice of self-managing its consequences. PMID:8138472

  16. Immune Evasion Strategies of Glioblastoma

    PubMed Central

    Razavi, Seyed-Mostafa; Lee, Karen E.; Jin, Benjamin E.; Aujla, Parvir S.; Gholamin, Sharareh; Li, Gordon

    2016-01-01

    Glioblastoma (GBM) is the most devastating brain tumor, with associated poor prognosis. Despite advances in surgery and chemoradiation, the survival of afflicted patients has not improved significantly in the past three decades. Immunotherapy has been heralded as a promising approach in treatment of various cancers; however, the immune privileged environment of the brain usually curbs the optimal expected response in central nervous system malignancies. In addition, GBM cells create an immunosuppressive microenvironment and employ various methods to escape immune surveillance. The purpose of this review is to highlight the strategies by which GBM cells evade the host immune system. Further understanding of these strategies and the biology of this tumor will pave the way for developing novel immunotherapeutic approaches for treatment of GBM. PMID:26973839

  17. Analysis of pilot control strategy

    NASA Technical Reports Server (NTRS)

    Heffley, R. K.; Hanson, G. D.; Jewell, W. F.; Clement, W. F.

    1983-01-01

    Methods for nonintrusive identification of pilot control strategy and task execution dynamics are presented along with examples based on flight data. The specific analysis technique is Nonintrusive Parameter Identification Procedure (NIPIP), which is described in a companion user's guide (NASA CR-170398). Quantification of pilot control strategy and task execution dynamics is discussed in general terms followed by a more detailed description of how NIPIP can be applied. The examples are based on flight data obtained from the NASA F-8 digital fly by wire airplane. These examples involve various piloting tasks and control axes as well as a demonstration of how the dynamics of the aircraft itself are identified using NIPIP. Application of NIPIP to the AFTI/F-16 flight test program is discussed. Recommendations are made for flight test applications in general and refinement of NIPIP to include interactive computer graphics.

  18. Hermes rescue strategies during launch

    NASA Astrophysics Data System (ADS)

    Cledassou, Rodelphe

    Safety and rescue strategies during the launch of Hermes space plane by Ariane 5 are discussed. Before solid booster separation, the pilots must be ejected by seats which are later recovered. After solid booster separation it becomes possible to extract the plane, which can perform a reentry leading to an available landing site or to sea recovery. When there is no useful landing site, the plane can be injected on a downgraded orbit.

  19. Introduction strategies raise key questions.

    PubMed

    Finger, W R; Keller, S

    1995-09-01

    Key issues that must be considered before a new contraceptive is introduced center on the need for a trained provider to begin or terminate the method, its side effects, duration of use, method's ability to meet users' needs and preferences, and extra training or staff requirements. Logistics and economic issues to consider are identifying a dependable way of effectively supplying commodities, planning extra services needed for the method, and cost of providing the method. Each contraceptive method presents a different side effect pattern and burdens the service delivery setting differently. The strategy developed to introduce or expand the 3-month injectable Depo-Provera (DMPA) can be used for any method. It includes a needs assessment and addresses regulatory issues, service delivery policies and procedures, information and training, evaluation, and other concerns. Viet Nam's needs assessment showed that Norplant should not be introduced until the service delivery system becomes stronger. Any needs assessment for expansion of contraceptive services should cover sexually transmitted disease/HIV issues. A World Health Organization strategy helps officials identify the best method mix for local situations. Introductory strategies must aim to improve the quality of family planning programs and expand choices. Many begin by examining existing data and conducting interviews with policymakers, users, providers, and women's health advocates. Introductory programs for Norplant focus on provider training, adequate counseling and informed consent for users, and ready access to removal. They need a well-prepared service delivery infrastructure. The first phase of the DMPA introductory strategy for the Philippines comprised a social marketing campaign and DMPA introduction at public clinics in 10 pilot areas with strong service delivery. Successful AIDS prevention programs show that people tend to use barrier methods when they are available. USAID is currently studying

  20. Strategies that fit emerging markets.

    PubMed

    Khanna, Tarun; Palepu, Krishna G; Sinha, Jayant

    2005-06-01

    It's no easy task to identify strategies for entering new international markets or to decide which countries to do business with. Many firms simply go with what they know-and fall far short of their goals. Part of the problem is that emerging markets have "institutional voids": They lack specialized intermediaries, regulatory systems, and contract-enforcing methods. These gaps have made it difficult for multinationals to succeed in developing nations; thus, many companies have resisted investing there. That may be a mistake. If Western companies don't come up with good strategies for engaging with emerging markets, they are unlikely to remain competitive. Many firms choose their markets and strategies for the wrong reasons, relying on everything from senior managers' gut feelings to the behaviors of rivals. Corporations also depend on composite indexes for help making decisions. But these analyses can be misleading; they don't account for vital information about the soft infrastructures in developing nations. A better approach is to understand institutional variations between countries. The best way to do this, the authors have found, is by using the five contexts framework. The five contexts are a country's political and social systems, its degree of openness, its product markets, its labor markets, and its capital markets. By asking a series of questions that pertain to each ofthe five areas, executives can map the institutional contexts of any nation. When companies match their strategies to each country's contexts, they can take advantage of a location's unique strengths. But first firms should weigh the benefits against the costs. If they find that the risks of adaptation are too great, they should try to change the contexts in which they operate or simply stay away. PMID:15938439

  1. Strategies for cell membrane functionalization

    PubMed Central

    Armstrong, James PK

    2016-01-01

    The ability to rationally manipulate and augment the cytoplasmic membrane can be used to overcome many of the challenges faced by conventional cellular therapies and provide innovative opportunities when combined with new biotechnologies. The focus of this review is on emerging strategies used in cell functionalization, highlighting both pioneering approaches and recent developments. These will be discussed within the context of future directions in this rapidly evolving field. PMID:27229904

  2. TREAT Modeling and Simulation Strategy

    SciTech Connect

    DeHart, Mark David

    2015-09-01

    This report summarizes a four-phase process used to describe the strategy in developing modeling and simulation software for the Transient Reactor Test Facility. The four phases of this research and development task are identified as (1) full core transient calculations with feedback, (2) experiment modeling, (3) full core plus experiment simulation and (4) quality assurance. The document describes the four phases, the relationship between these research phases, and anticipated needs within each phase.

  3. Dispersion as a Survival Strategy

    NASA Astrophysics Data System (ADS)

    Junior, Valdivino Vargas; Machado, Fábio Prates; Roldán-Correa, Alejandro

    2016-08-01

    We consider stochastic growth models to represent population subject to catastrophes. We analyze the subject from different set ups considering or not spatial restrictions, whether dispersion is a good strategy to increase the population viability. We find out it strongly depends on the effect of a catastrophic event, the spatial constraints of the environment and the probability that each exposed individual survives when a disaster strikes.

  4. Communication patterns and allocation strategies.

    SciTech Connect

    Leung, Vitus Joseph; Mache, Jens Wolfgang; Bunde, David P.

    2004-01-01

    Motivated by observations about job runtimes on the CPlant system, we use a trace-driven microsimulator to begin characterizing the performance of different classes of allocation algorithms on jobs with different communication patterns in space-shared parallel systems with mesh topology. We show that relative performance varies considerably with communication pattern. The Paging strategy using the Hilbert space-filling curve and the Best Fit heuristic performed best across several communication patterns.

  5. Voyager navigation strategy and accuracy

    NASA Technical Reports Server (NTRS)

    Jones, J. B.; Mcdanell, J. P.; Bantell, M. H., Jr.; Chadwick, C.; Jacobson, R. A.; Miller, L. J.; Synnott, S. P.; Van Allen, R. E.

    1977-01-01

    The paper presents the results of the prelaunch navigation studies conducted for the Mariner spacecraft launched toward encounters with the giant planets. The navigation system and the strategy for using this system are described. The requirements on the navigation system demanded by the goals of the project are mentioned, and the predicted navigational capability relative to each of the requirements is discussed. Baseline navigation results for three possible trajectories are analyzed.

  6. Selected synthetic strategies to cyclophanes

    PubMed Central

    2015-01-01

    Summary In this review we cover various approaches to meta- and paracyclophanes involving popular reactions. Generally, we have included a strategy where the reaction was used for assembling the cyclophane skeleton for further functionalization. In several instances, after the cyclophane is made several popular reactions are used and these are not covered here. We included various natural products related to cyclophanes. To keep the length of the review at a manageable level the literature related to orthocyclophanes was not included. PMID:26425186

  7. Revision IPAA: strategies for success.

    PubMed

    Larson, David W

    2014-07-01

    The history of ileal pouch-anal anastomosis (IPAA) is one of success with durable surgical and functional results. However, pouch failure, due to infection, mechanical, or functional disability, represents a challenge to both surgeon and patient. Practicing surgeons who deal with the revision pouch face a variety of challenges. Success requires a strategy, which includes critical planning, preparation, and surgical techniques in order that surgeons continue to provide solutions and hope to patients.

  8. Stabilization strategies for unstable dynamics.

    PubMed

    Morasso, Pietro; Casadio, Maura; De Santis, Dalia; Nomura, Taishin; Rea, Francesco; Zenzeri, Jacopo

    2014-12-01

    The stabilization of the human standing posture was originally attributed to the stiffness of the ankle muscles but direct measurements of the ankle stiffness ruled out this hypothesis, leaving open the possibility for a feedback stabilization strategy driven by proprioceptive signals. This solution, however, could be implemented with two different kinds of control mechanisms, namely continuous or intermittent feedback. The debate is now settled and the latter solution seems to be the most plausible one. Moreover, stabilization of unstable dynamics is not limited to bipedal standing. Indeed many manipulation tasks can be described in the same framework and thus a very general protocol for addressing this kind of problems is the use of haptic virtual reality where instability is generated by some kind of divergent or saddle-like force field. Several studies demonstrated that human subjects can choose to adopt a stiffness or feedback strategy as a combination of biomechanical and task constraints and can learn to switch from one strategy to the other if it is feasible or to use one or the other is infeasible. Understanding such mechanisms is relevant, for example, for the design of novel ergonomic man-machine interfaces in difficult, unstable tasks. PMID:25453479

  9. U.S. space strategy

    NASA Astrophysics Data System (ADS)

    Robb, David W.

    1984-04-01

    Following the formal announcement of a national space strategy in August, President Ronald Reagan is moving ahead on many of his administration's declared objectives for strengthening the U.S. role in space-based research and space exploration.Possibly the most significant long-term aspect of the administration's national space strategy is its emphasis on international cooperation. While the U.S. space program in the 1960s and 1970s was fueled by intense competition in the race to be the first to put a man on the moon, it may very well be characterized through the beginning of the next century by the spirit of international collaboration. The national space strategy calls for “increased international cooperation in civil space activities,” particularly in the “development and utilization” of the space station. In addition, in late October, President Reagan announced the possibility of a joint U.S.-Soviet simulated space rescue mission. In his statement, Reagan said that the U.S. “is prepared to work with the Soviets on cooperation in space in programs which are mutually beneficial and productive.”

  10. Regenerative Strategies for Craniofacial Disorders

    PubMed Central

    Garland, Catharine B.; Pomerantz, Jason H.

    2012-01-01

    Craniofacial disorders present markedly complicated problems in reconstruction because of the complex interactions of the multiple, simultaneously affected tissues. Regenerative medicine holds promise for new strategies to improve treatment of these disorders. This review addresses current areas of unmet need in craniofacial reconstruction and emphasizes how craniofacial tissues differ from their analogs elsewhere in the body. We present a problem-based approach to illustrate current treatment strategies for various craniofacial disorders, to highlight areas of need, and to suggest regenerative strategies for craniofacial bone, fat, muscle, nerve, and skin. For some tissues, current approaches offer excellent reconstructive solutions using autologous tissue or prosthetic materials. Thus, new “regenerative” approaches would need to offer major advantages in order to be adopted. In other tissues, the unmet need is great, and we suggest the greatest regenerative need is for muscle, skin, and nerve. The advent of composite facial tissue transplantation and the development of regenerative medicine are each likely to add important new paradigms to our treatment of craniofacial disorders. PMID:23248598

  11. Do quantum strategies always win?

    NASA Astrophysics Data System (ADS)

    Anand, Namit; Benjamin, Colin

    2015-11-01

    In a seminal paper, Meyer (Phys Rev Lett 82:1052, 1999) described the advantages of quantum game theory by looking at the classical penny flip game. A player using a quantum strategy can win against a classical player almost 100 % of the time. Here we make a slight modification to the quantum game, with the two players sharing an entangled state to begin with. We then analyze two different scenarios: First in which quantum player makes unitary transformations to his qubit, while the classical player uses a pure strategy of either flipping or not flipping the state of his qubit. In this case, the quantum player always wins against the classical player. In the second scenario, we have the quantum player making similar unitary transformations, while the classical player makes use of a mixed strategy wherein he either flips or not with some probability " p." We show that in the second scenario, 100 % win record of a quantum player is drastically reduced and for a particular probability " p" the classical player can even win against the quantum player. This is of possible relevance to the field of quantum computation as we show that in this quantum game of preserving versus destroying entanglement a particular classical algorithm can beat the quantum algorithm.

  12. Strategies to Reduce Indoor Tanning

    PubMed Central

    Holman, Dawn M.; Fox, Kathleen A.; Glenn, Jeffrey D.; Guy, Gery P.; Watson, Meg; Baker, Katie; Cokkinides, Vilma; Gottlieb, Mark; Lazovich, DeAnn; Perna, Frank M.; Sampson, Blake P.; Seidenberg, Andrew B.; Sinclair, Craig; Geller, Alan C.

    2015-01-01

    Exposure to ultraviolet radiation from indoor tanning device use is associated with an increased risk of skin cancer, including risk of malignant melanoma, and is an urgent public health problem. By reducing indoor tanning, future cases of skin cancer could be prevented, along with the associated morbidity, mortality, and healthcare costs. On August 20, 2012, the CDC hosted a meeting to discuss the current body of evidence on strategies to reduce indoor tanning as well as research gaps. Using the Action Model to Achieve Healthy People 2020 Overarching Goals as a framework, the current paper provides highlights on the topics that were discussed, including (1) the state of the evidence on strategies to reduce indoor tanning; (2) the tools necessary to effectively assess, monitor, and evaluate the short- and long-term impact of interventions designed to reduce indoor tanning; and (3) strategies to align efforts at the national, state, and local levels through transdisciplinary collaboration and coordination across multiple sectors. Although many challenges and barriers exist, a coordinated, multilevel, transdisciplinary approach has the potential to reduce indoor tanning and prevent future cases of skin cancer. PMID:23683986

  13. Dietary strategies for weight management.

    PubMed

    Rolls, Barbara J

    2012-01-01

    In an 'obesogenic' environment, getting people to eat appropriate amounts is challenging. Several food-based strategies have the potential to promote satiety and moderate energy intake. Components of foods such as macronutrients and functional ingredients can affect satiety; however, for weight management a more comprehensive approach is needed that emphasizes behavioral strategies to improve the overall diet. Research shows that large portions of energy-dense foods facilitate overconsumption and that reductions in portion size and energy density are associated with reduced energy intake. While this suggests that people should eat smaller portions, recent data show that if people lower the energy density of their diet, they can continue to eat their usual amount of food while limiting calories. Furthermore, serving larger portions of low-energy-dense foods can be used strategically to encourage their consumption and reduce dietary energy density, and this has been shown to be associated with decreased energy intake while maintaining satiety. This new understanding of how portion size can be used positively to manage energy intake has the potential to help people achieve sustainable improvements in their energy intake and bodyweight. Science-based strategies that increase the availability of affordable nutrient-rich, lower energy-dense foods are urgently needed. PMID:23128764

  14. Updated NGNP Fuel Acquisition Strategy

    SciTech Connect

    David Petti; Tim Abram; Richard Hobbins; Jim Kendall

    2010-12-01

    A Next Generation Nuclear Plant (NGNP) fuel acquisition strategy was first established in 2007. In that report, a detailed technical assessment of potential fuel vendors for the first core of NGNP was conducted by an independent group of international experts based on input from the three major reactor vendor teams. Part of the assessment included an evaluation of the credibility of each option, along with a cost and schedule to implement each strategy compared with the schedule and throughput needs of the NGNP project. While credible options were identified based on the conditions in place at the time, many changes in the assumptions underlying the strategy and in externalities that have occurred in the interim requiring that the options be re-evaluated. This document presents an update to that strategy based on current capabilities for fuel fabrication as well as fuel performance and qualification testing worldwide. In light of the recent Pebble Bed Modular Reactor (PBMR) project closure, the Advanced Gas Reactor (AGR) fuel development and qualification program needs to support both pebble and prismatic options under the NGNP project. A number of assumptions were established that formed a context for the evaluation. Of these, the most important are: • Based on logistics associated with the on-going engineering design activities, vendor teams would start preliminary design in October 2012 and complete in May 2014. A decision on reactor type will be made following preliminary design, with the decision process assumed to be completed in January 2015. Thus, no fuel decision (pebble or prismatic) will be made in the near term. • Activities necessary for both pebble and prismatic fuel qualification will be conducted in parallel until a fuel form selection is made. As such, process development, fuel fabrication, irradiation, and testing for pebble and prismatic options should not negatively influence each other during the period prior to a decision on reactor type

  15. Coping Strategies in Psychiatric Clinical Research.

    ERIC Educational Resources Information Center

    Kraemer, Helena Chmura

    1981-01-01

    A broad range of strategies in sampling, measurement, design, execution, implementation, and analysis are examined. Specific strategies are suggested that tend to be successful in the real world of psychiatric clinical research. (Author)

  16. Pursuit and Evasion Strategies in Football.

    ERIC Educational Resources Information Center

    O'Connell, James

    1995-01-01

    Explores strategies in the situation of a runner trying to evade a tackler on a football field. Enables the student to test intuitive strategies in a familiar situation using simple graphical and numerical methods or direct experimentation. (JRH)

  17. Managing Change: Attitudes, Targets, Problems, and Strategies.

    ERIC Educational Resources Information Center

    Powell, Gary N.; Posner, Barry Z.

    1980-01-01

    Managers need to be skilled at diagnosing the demands of a situation and flexible in selecting and implementing a change strategy tailored to the demands. A model for selecting appropriate change strategies is presented. (Author)

  18. Picking the right transition strategy.

    PubMed

    Watkins, Michael D

    2009-01-01

    Leaders in transition reflexively rely on the skills and strategies that worked for them in the past. That's a mistake, says Watkins, whose research shows that executives moving into new roles must gain a deep understanding of the situation at hand and adapt to it. To help them accurately assess their organizations and tailor their strategies and styles accordingly, he developed the STARS framework. "STARS" is an acronym for the five common situations leaders move into: start-up, turnaround, accelerated growth, realignment, and sustaining success. Thus, the model outlines the challenges of launching a venture or project; saving a business or initiative that's in serious trouble; dealing with rapid expansion; reenergizing a once-leading company that's now facing problems; and following in the footsteps of a highly regarded leader with a strong legacy of success. Executives can accelerate their immersion in new roles by following certain fundamental principles: Organize to learn about the business, establish A-item priorities, define strategic intent, quickly build the leadership team, secure early wins, and create supportive alliances across the company. But the way those principles should be applied depends very much on the business situation, which the STARS framework can help leaders analyze. Turnarounds and realignments present especially distinct leadership challenges that call for particular transition strategies. Regardless of the business situation, leaders must figure out which things need to happen--perhaps a jump in market share or an expansion into different markets--for their business to achieve its goals. And they must determine which leadership style best fits the new culture they're joining. Armed with such clarity, executives can design effective plans to manage their organizations and themselves.

  19. Strategies to Prevent Preterm Birth

    PubMed Central

    Newnham, John P.; Dickinson, Jan E.; Hart, Roger J.; Pennell, Craig E.; Arrese, Catherine A.; Keelan, Jeffrey A.

    2014-01-01

    After several decades of research, we now have evidence that at least six interventions are suitable for immediate use in contemporary clinical practice within high-resource settings and can be expected to safely reduce the rate of preterm birth. These interventions involve strategies to prevent non-medically indicated late preterm birth; use of maternal progesterone supplementation; surgical closure of the cervix with cerclage; prevention of exposure of pregnant women to cigarette smoke; judicious use of fertility treatments; and dedicated preterm birth prevention clinics. Quantification of the extent of success is difficult to predict and will be dependent on other clinical, cultural, societal, and economic factors operating in each environment. Further success can be anticipated in the coming years as other research discoveries are translated into clinical practice, including new approaches to treating intra-uterine infection, improvements in maternal nutrition, and lifestyle modifications to ameliorate maternal stress. The widespread use of human papillomavirus vaccination in girls and young women will decrease the need for surgical interventions on the cervix and can be expected to further reduce the risk of early birth. Together, this array of clinical interventions, each based on a substantial body of evidence, is likely to reduce rates of preterm birth and prevent death and disability in large numbers of children. The process begins with an acceptance that early birth is not an inevitable and natural feature of human reproduction. Preventative strategies are now available and need to be applied. The best outcomes may come from developing integrated strategies designed specifically for each health-care environment. PMID:25477878

  20. INL High Performance Building Strategy

    SciTech Connect

    Jennifer D. Morton

    2010-02-01

    High performance buildings, also known as sustainable buildings and green buildings, are resource efficient structures that minimize the impact on the environment by using less energy and water, reduce solid waste and pollutants, and limit the depletion of natural resources while also providing a thermally and visually comfortable working environment that increases productivity for building occupants. As Idaho National Laboratory (INL) becomes the nation’s premier nuclear energy research laboratory, the physical infrastructure will be established to help accomplish this mission. This infrastructure, particularly the buildings, should incorporate high performance sustainable design features in order to be environmentally responsible and reflect an image of progressiveness and innovation to the public and prospective employees. Additionally, INL is a large consumer of energy that contributes to both carbon emissions and resource inefficiency. In the current climate of rising energy prices and political pressure for carbon reduction, this guide will help new construction project teams to design facilities that are sustainable and reduce energy costs, thereby reducing carbon emissions. With these concerns in mind, the recommendations described in the INL High Performance Building Strategy (previously called the INL Green Building Strategy) are intended to form the INL foundation for high performance building standards. This revised strategy incorporates the latest federal and DOE orders (Executive Order [EO] 13514, “Federal Leadership in Environmental, Energy, and Economic Performance” [2009], EO 13423, “Strengthening Federal Environmental, Energy, and Transportation Management” [2007], and DOE Order 430.2B, “Departmental Energy, Renewable Energy, and Transportation Management” [2008]), the latest guidelines, trends, and observations in high performance building construction, and the latest changes to the Leadership in Energy and Environmental Design

  1. On dormancy strategies in tardigrades.

    PubMed

    Guidetti, Roberto; Altiero, Tiziana; Rebecchi, Lorena

    2011-05-01

    In this review we analyze the dormancy strategies of metazoans inhabiting "hostile to life" habitats, which have a strong impact on their ecology and in particular on the traits of their life history. Tardigrades are here considered a model animal, being aquatic organisms colonizing terrestrial habitats. Tardigrades evolved a large variety of dormant stages that can be ascribed to diapause (encystment, cyclomorphosis, resting eggs) and cryptobiosis (anhydrobiosis, cryobiosis, anoxibiosis). In tardigrades, diapause and cryptobiosis can occur separately or simultaneously, consequently the adoption of one adaptive strategy is not necessarily an alternative to the adoption of the other. Encystment and cyclomorphosis are characterized by seasonal cyclic changes in morphology and physiology of the animals. They share several common features and their evolution is strictly linked to the molting process. A bet-hedging strategy with different patterns of egg hatching time has been observed in a tardigrade species. Four categories of eggs have been identified: subitaneous, delayed-hatching, abortive and diapause resting eggs, which needs a stimulus to hatch (rehydration after a period of desiccation). Cryptobiotic tardigrades are able to withstand desiccation (anhydrobiosis) and freezing (cryobiosis) at any stage of their life-cycle. This ability involves a complex array of factors working at molecular (bioprotectans), physiological and structural levels. Animal survival and the accumulation of molecular damage are related to the time spent in the cryptobiotic state, to the abiotic parameters during the cryptobiotic state, and to the conditions during initial and final phases of the process. Cryptobiosis evolved independently at least two times in tardigrades, in eutardigrades and in echiniscoids. Within each evolutionary line, the absence of cryptobiotic abilities is more related to selective pressures to local habitat adaptation than to phylogenetic relationships. The

  2. Vaccination strategies for Parkinson disease

    PubMed Central

    Romero-Ramos, Marina; von Euler Chelpin, Marianne; Sanchez-Guajardo, Vanesa

    2014-01-01

    Parkinson disease is the second most common neurodegenerative disease in the world, but there is currently no available cure for it. Current treatments only alleviate some of the symptoms for a few years, but they become ineffective in the long run and do not stop the disease. Therefore it is of outmost importance to develop therapeutic strategies that can prevent, stop, or cure Parkinson disease. A very promising target for these therapies is the peripheral immune system due to its probable involvement in the disease and its potential as a tool to modulate neuroinflammation. But for such strategies to be successful, we need to understand the particular state of the peripheral immune system during Parkinson disease in order to avoid its weaknesses. In this review we examine the available data regarding how dopamine regulates the peripheral immune system and how this regulation is affected in Parkinson disease; the specific cytokine profiles observed during disease progression and the alterations documented to date in patients’ peripheral blood mononuclear cells. We also review the different strategies used in Parkinson disease animal models to modulate the adaptive immune response to salvage dopaminergic neurons from cell death. After analyzing the evidence, we hypothesize the need to prime the immune system to restore natural tolerance against α-synuclein in Parkinson disease, including at the same time B and T cells, so that T cells can reprogram microglia activation to a beneficial pattern and B cell/IgG can help neurons cope with the pathological forms of α-synuclein. PMID:24670306

  3. On dormancy strategies in tardigrades.

    PubMed

    Guidetti, Roberto; Altiero, Tiziana; Rebecchi, Lorena

    2011-05-01

    In this review we analyze the dormancy strategies of metazoans inhabiting "hostile to life" habitats, which have a strong impact on their ecology and in particular on the traits of their life history. Tardigrades are here considered a model animal, being aquatic organisms colonizing terrestrial habitats. Tardigrades evolved a large variety of dormant stages that can be ascribed to diapause (encystment, cyclomorphosis, resting eggs) and cryptobiosis (anhydrobiosis, cryobiosis, anoxibiosis). In tardigrades, diapause and cryptobiosis can occur separately or simultaneously, consequently the adoption of one adaptive strategy is not necessarily an alternative to the adoption of the other. Encystment and cyclomorphosis are characterized by seasonal cyclic changes in morphology and physiology of the animals. They share several common features and their evolution is strictly linked to the molting process. A bet-hedging strategy with different patterns of egg hatching time has been observed in a tardigrade species. Four categories of eggs have been identified: subitaneous, delayed-hatching, abortive and diapause resting eggs, which needs a stimulus to hatch (rehydration after a period of desiccation). Cryptobiotic tardigrades are able to withstand desiccation (anhydrobiosis) and freezing (cryobiosis) at any stage of their life-cycle. This ability involves a complex array of factors working at molecular (bioprotectans), physiological and structural levels. Animal survival and the accumulation of molecular damage are related to the time spent in the cryptobiotic state, to the abiotic parameters during the cryptobiotic state, and to the conditions during initial and final phases of the process. Cryptobiosis evolved independently at least two times in tardigrades, in eutardigrades and in echiniscoids. Within each evolutionary line, the absence of cryptobiotic abilities is more related to selective pressures to local habitat adaptation than to phylogenetic relationships. The

  4. Estate Strategies: A Guide to Good Practice.

    ERIC Educational Resources Information Center

    Higher Education Funding Council for England, Bristol.

    This guide explores key points in the development and execution of estate strategies for institutions of higher education, including: discussions on the benefits of an estate strategy; a list of self-assessment questions to consider; a breakdown of the strategy process, roles and responsibilities of various stakeholders; and the estate strategy…

  5. Strategies of Qualitative Inquiry. Third Edition

    ERIC Educational Resources Information Center

    Denzin, Norman K., Ed.; Lincoln, Yvonna S., Ed.

    2007-01-01

    "Strategies of Qualitative Inquiry, Third Edition," the second volume in the paperback version of "The SAGE Handbook of Qualitative Research, 3rd Edition," consists of Part III of the handbook ("Strategies of Inquiry"). "Strategies of Qualitative Inquiry, Third Edition" presents the major tactics--historically, the research methods--that…

  6. Teaching Reading Strategies to English Language Learners.

    ERIC Educational Resources Information Center

    Jenks, Christopher J.

    This paper discusses the importance of teaching English language learners (ELLs) three reading strategies to help facilitate a productive literacy environment, suggesting that students must be taught specific reading strategies in which purpose, comprehension, and memorization are facilitated. The first section presents a pre-reading strategy,…

  7. Request Strategies in British English and Japanese.

    ERIC Educational Resources Information Center

    Fukushima, Saeko

    1996-01-01

    Tests request strategies used by speakers of Japanese and British English in two culturally neutral situations likely to trigger a request. Concludes that the degree of imposition goes on a par with the number of politeness strategies but that there are differences in the types of strategies used: the British use conventional forms and supportive…

  8. Hawaii energy strategy report, October 1995

    SciTech Connect

    1995-10-01

    This is a report on the Hawaii Energy Strategy Program. The topics of the report include the a description of the program including an overview, objectives, policy statement and purpose and objectives; energy strategy policy development; energy strategy projects; current energy situation; modeling Hawaii`s energy future; energy forecasts; reducing energy demand; scenario assessment, and recommendations.

  9. Effective Social Interaction Strategies for Inclusive Settings

    ERIC Educational Resources Information Center

    Terpstra, Judith E.; Tamura, Ronald

    2008-01-01

    Many strategies and interventions exist in the education of young children with disabilities. One area of intervention is that of social interaction, including social skills instruction, peer interaction strategies, and play skills. Interaction and social skill strategies for use with children with and without disabilities for the purpose of…

  10. Teaching Reading Strategies in the School Library

    ERIC Educational Resources Information Center

    Walker, Christine; Shaw, Sarah

    2004-01-01

    Walker and Shaw link the teaching of ten commonly taught reading strategies such as sequencing, compare and contrast, and prediction to newly published picture book titles. Each chapter of the book provides a strategy, a graphic organizer to teach it with, and an in- depth modeled discussion of how to use the strategy with two or three books.…

  11. From Strategic Intent to Strategy: The "Gap"

    ERIC Educational Resources Information Center

    Knoess, Christoph

    2005-01-01

    "Strategic planning results in plans, not strategies." This admission by Gary Hamel, one of the foremost business thinkers of the times, sums up the dilemma of many institutions of higher education. While they each have a mission supported by a strategic plan, many don't seem to have a demonstrable strategy. An institution's strategy is not…

  12. Cosmetology Reading Strategies. 1980 Vocational Reading Series.

    ERIC Educational Resources Information Center

    Thornton, L. Jay; And Others

    Cosmetology Reading Strategies is one of five instructional guides in the Reading Strategies in Vocational Education Series. Developed to assist teachers working with students considered disadvantaged because of reading deficiency, the guide contains several strategies, suitable for adaptation, specifically related to cosmetology instruction. Each…

  13. Revealing the Effectivenesses of Communication Strategies

    ERIC Educational Resources Information Center

    Lin, Grace Hui Chin

    2013-01-01

    The purpose of this study is to report the history of communication strategy and highlight the importance of strategic competence. It provides the histories and characterizations of communication strategy. Besides, it presents from which perspectives these definitions of communication strategies were developed. Various earlier and latter…

  14. 40 CFR 52.07 - Control strategies.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Control strategies. 52.07 Section 52.07... PROMULGATION OF IMPLEMENTATION PLANS General Provisions § 52.07 Control strategies. (a) Each subpart specifies in what respects the control strategies are approved or disapproved. Where emission limitations...

  15. 40 CFR 52.07 - Control strategies.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... national standard which the requirement is intended to implement. (b) A control strategy may be disapproved... 40 Protection of Environment 3 2013-07-01 2013-07-01 false Control strategies. 52.07 Section 52.07... PROMULGATION OF IMPLEMENTATION PLANS General Provisions § 52.07 Control strategies. (a) Each subpart...

  16. 40 CFR 52.07 - Control strategies.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... national standard which the requirement is intended to implement. (b) A control strategy may be disapproved... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Control strategies. 52.07 Section 52.07... PROMULGATION OF IMPLEMENTATION PLANS General Provisions § 52.07 Control strategies. (a) Each subpart...

  17. 40 CFR 52.07 - Control strategies.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... national standard which the requirement is intended to implement. (b) A control strategy may be disapproved... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Control strategies. 52.07 Section 52.07... PROMULGATION OF IMPLEMENTATION PLANS General Provisions § 52.07 Control strategies. (a) Each subpart...

  18. 48 CFR 1034.004 - Acquisition strategy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... “lock in”. (b) The acquisition strategy shall be approved by a chartered interdisciplinary acquisition... 48 Federal Acquisition Regulations System 5 2013-10-01 2013-10-01 false Acquisition strategy. 1034... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 1034.004 Acquisition strategy. (a) A...

  19. 48 CFR 1034.004 - Acquisition strategy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... “lock in”. (b) The acquisition strategy shall be approved by a chartered interdisciplinary acquisition... 48 Federal Acquisition Regulations System 5 2014-10-01 2014-10-01 false Acquisition strategy. 1034... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 1034.004 Acquisition strategy. (a) A...

  20. Learning Strategies for Adolescents with Mild Disabilities

    ERIC Educational Resources Information Center

    Conderman, Greg; Koman, Kara; Schibelka, Mary; Higgin, Karen; Cooper, Cody; Butler, Jordyn

    2013-01-01

    Learning strategy instruction is an evidence-based practice for teaching adolescents with mild disabilities. However, researchers have not developed strategies for every content area or skill. Therefore, teachers need to be able develop strategies based on the needs of their students. This article reviews the process for developing and teaching…

  1. Language Learning Strategies and Its Training Model

    ERIC Educational Resources Information Center

    Liu, Jing

    2010-01-01

    This paper summarizes and reviews the literature regarding language learning strategies and it's training model, pointing out the significance of language learning strategies to EFL learners and an applicable and effective language learning strategies training model, which is beneficial both to EFL learners and instructors, is badly needed.

  2. Three Strategies for Effective Data Oversight

    ERIC Educational Resources Information Center

    Huwe, Terence K.

    2009-01-01

    This article discusses three strategies for building a data center or service. These strategies are: (1) "audit" a way to alliances; (2) "share" oversight but "own" the warehouse; and (3) join new professional "cultures." These strategies have more to do with people and organizations than technology since technology mirrors and amplifies what…

  3. Dealing with Resistance: Strategies for Effective Group.

    ERIC Educational Resources Information Center

    Higgs, Judith A.

    1992-01-01

    Describes strategies for dealing effectively with resistance in group therapy. Discusses resistant group members; reasons for resistance; group stages; and strategies for dealing with silence, laughter, excessive talking, monopolizing, and intellectualizing and generalizing. Includes discussion of experimental strategies to overcome group…

  4. Pricing Strategies for CD-ROM Products.

    ERIC Educational Resources Information Center

    Rowley, J. E.

    1994-01-01

    Pricing strategies for subscriptions and licenses for CD-ROMs are different for single users and networks. The basic components of pricing strategies are charges for subscription, connect line, display/print, telecommunication, session rate, special commands, and special services. Highlights selected supplier pricing strategies for single users…

  5. Reconnecting Strategy Instruction with Its Theoretical Roots

    ERIC Educational Resources Information Center

    Palincsar, Annemarie Sullivan; Schutz, Kristine M.

    2011-01-01

    This article revisits the rich theoretical and empirical literatures that undergird strategy instruction, with the goal of identifying a principled approach to the teaching of strategies to enhance reading and learning with text. Its purpose is to examine the question of why strategy instruction, as enacted in practice, might raise concerns among…

  6. 2011 National Drug Control Strategy. Executive Summary

    ERIC Educational Resources Information Center

    Office of National Drug Control Policy, 2011

    2011-01-01

    In May of 2010, President Obama released the Administration's inaugural "National Drug Control Strategy", a comprehensive approach to combat the public health and safety consequences posed by drug use. Now, a year later, the Administration is releasing its update building upon that initial "Strategy". The "Strategy" establishes ambitious goals to…

  7. Coping Strategies in Young Male Prisoners

    ERIC Educational Resources Information Center

    Mohino, Susana; Kirchner, Teresa; Forns, Maria

    2004-01-01

    The general aim of this study is to analyze diverse aspects relating to the use of coping strategies among prison inmates. The specific objectives are (a) to analyze which type of coping strategies predominate among prisoners, considering both the focus and the method; (b) to relate the use of coping strategies with variables related to the prison…

  8. The Challenge of Measuring Language Learning Strategies

    ERIC Educational Resources Information Center

    Woodrow, Lindy

    2005-01-01

    This article discusses the usefulness of using generic strategy inventories to assess language learning strategies (LLSs) across contexts. A review of the LLS research is presented with a critique of extant studies in relation to classification of strategies, methodological issues, and the predictability of language performance. The present…

  9. 24 CFR 954.103 - Housing strategy.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Housing strategy. 954.103 Section... INDIAN HOME PROGRAM Applying for Assistance § 954.103 Housing strategy. Grantees are not required to submit a housing strategy to receive HOME funds. However, the application must demonstrate how...

  10. 48 CFR 1034.004 - Acquisition strategy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 5 2011-10-01 2011-10-01 false Acquisition strategy. 1034... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 1034.004 Acquisition strategy. (a) A program manager's acquisition strategy written at the system or investment level in accordance with FAR...

  11. 48 CFR 3034.004 - Acquisition strategy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Acquisition strategy. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider... 48 Federal Acquisition Regulations System 7 2011-10-01 2011-10-01 false Acquisition strategy. 3034.004 Section 3034.004 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY,...

  12. 29 CFR 42.6 - Enforcement strategy.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Enforcement strategy. 42.6 Section 42.6 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.6 Enforcement strategy. (a) Each Regional Farm Labor... enforcement strategy for each protective statute pursuant to § 42.20(c)(3). The National Committee...

  13. 40 CFR 52.07 - Control strategies.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Control strategies. 52.07 Section 52.07... PROMULGATION OF IMPLEMENTATION PLANS General Provisions § 52.07 Control strategies. (a) Each subpart specifies in what respects the control strategies are approved or disapproved. Where emission limitations...

  14. 48 CFR 234.004 - Acquisition strategy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Acquisition strategy. 234..., DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION 234.004 Acquisition strategy. (1) See 209.570 for policy applicable to acquisition strategies that consider the use of lead...

  15. 48 CFR 234.004 - Acquisition strategy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Acquisition strategy. 234..., DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION 234.004 Acquisition strategy. (1) See 209.570 for policy applicable to acquisition strategies that consider the use of lead...

  16. 29 CFR 42.6 - Enforcement strategy.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 1 2011-07-01 2011-07-01 false Enforcement strategy. 42.6 Section 42.6 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.6 Enforcement strategy. (a) Each Regional Farm Labor... enforcement strategy for each protective statute pursuant to § 42.20(c)(3). The National Committee...

  17. 24 CFR 954.103 - Housing strategy.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Housing strategy. 954.103 Section... INDIAN HOME PROGRAM Applying for Assistance § 954.103 Housing strategy. Grantees are not required to submit a housing strategy to receive HOME funds. However, the application must demonstrate how...

  18. 48 CFR 34.004 - Acquisition strategy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Acquisition strategy. 34... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 34.004 Acquisition strategy. The program manager, as specified in agency procedures, shall develop an acquisition strategy tailored to the...

  19. 48 CFR 3034.004 - Acquisition strategy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Acquisition strategy. See (HSAR) 48 CFR 3009.570 for policy applicable to acquisition strategies that consider... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Acquisition strategy. 3034.004 Section 3034.004 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY,...

  20. 48 CFR 34.004 - Acquisition strategy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Acquisition strategy. 34... CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 34.004 Acquisition strategy. The program manager, as specified in agency procedures, shall develop an acquisition strategy tailored to the...

  1. Strategy Planning in Continuing Nursing Education.

    ERIC Educational Resources Information Center

    Aiken, Eula

    Corporate strategies that can be used in continuing nursing education programs are discussed, based on the Regional Action for Continuing Education in Nursing Education project. Attention is focused on strategies employed at Southern State University (SSU). A practical planning method was used to guide the process of corporate strategy formulation…

  2. Vocabulary Memorizing Strategies by Chinese University Students

    ERIC Educational Resources Information Center

    Yang, Wei-dong; Dai, Wei-ping

    2012-01-01

    The findings of the study indicate that students prefer to engage in the vocabulary learning strategies that would be most appealing to them and that would entail less manipulation of the language. Of the four vocabulary memorizing strategies cited in the study (rote repetition, structural associations, semantic strategies, and mnemonic keyword…

  3. Mining Social Entrepreneurship Strategies Using Topic Modeling.

    PubMed

    Chandra, Yanto; Jiang, Li Crystal; Wang, Cheng-Jun

    2016-01-01

    Despite the burgeoning research on social entrepreneurship (SE), SE strategies remain poorly understood. Drawing on extant research on the social activism and social change, empowerment and SE models, we explore, classify and validate the strategies used by 2,334 social entrepreneurs affiliated with the world's largest SE support organization, Ashoka. The results of the topic modeling of the social entrepreneurs' strategy profiles reveal that they employed a total of 39 change-making strategies that vary across resources (material versus symbolic strategies), specificity (general versus specific strategies), and mode of participation (mass versus elite participation strategies); they also vary across fields of practice and time. Finally, we identify six meta-SE strategies-a reduction from the 39 strategies-and identify four new meta-SE strategies (i.e., system reform, physical capital development, evidence-based practices, and prototyping) that have been overlooked in prior SE research. Our findings extend and deepen the research into SE strategies and offer a comprehensive model of SE strategies that advances theory, practice and policy making. PMID:26998970

  4. Mining Social Entrepreneurship Strategies Using Topic Modeling.

    PubMed

    Chandra, Yanto; Jiang, Li Crystal; Wang, Cheng-Jun

    2016-01-01

    Despite the burgeoning research on social entrepreneurship (SE), SE strategies remain poorly understood. Drawing on extant research on the social activism and social change, empowerment and SE models, we explore, classify and validate the strategies used by 2,334 social entrepreneurs affiliated with the world's largest SE support organization, Ashoka. The results of the topic modeling of the social entrepreneurs' strategy profiles reveal that they employed a total of 39 change-making strategies that vary across resources (material versus symbolic strategies), specificity (general versus specific strategies), and mode of participation (mass versus elite participation strategies); they also vary across fields of practice and time. Finally, we identify six meta-SE strategies-a reduction from the 39 strategies-and identify four new meta-SE strategies (i.e., system reform, physical capital development, evidence-based practices, and prototyping) that have been overlooked in prior SE research. Our findings extend and deepen the research into SE strategies and offer a comprehensive model of SE strategies that advances theory, practice and policy making.

  5. Hawaii energy strategy: Executive summary, October 1995

    SciTech Connect

    1995-10-01

    This is an executive summary to a report on the Hawaii Energy Strategy Program. The topics of the report include the a description of the program including an overview, objectives, policy statement and purpose and objectives; energy strategy policy development; energy strategy projects; current energy situation; modeling Hawaii`s energy future; energy forecasts; reducing energy demand; scenario assessment, and recommendations.

  6. Discrepant Stakeholder Perspectives on Graduate Employability Strategies

    ERIC Educational Resources Information Center

    Kinash, Shelley; Crane, Linda; Judd, Madelaine-Marie; Knight, Cecily

    2016-01-01

    A literature review identified 12 strategies that have been empirically linked to improvements in graduate employability. A survey methodology was used to investigate self-reported use and/or perspectives on these strategies among four stakeholder groups. The following questions were asked: to students--What strategies are you using to improve…

  7. Threaded Discussion Instructional Strategies and Student Performance

    ERIC Educational Resources Information Center

    Krull, Rodger Pratt

    2013-01-01

    Educators need insight into what instructional strategies are effective in the online environment, but few researchers have contrasted threaded discussion strategies and measures of student performance using a quantitative approach. Also, the effectiveness of threaded discussion strategies across all student generation groups or between genders is…

  8. Exploration strategies for hydrothermal deposits.

    PubMed

    Horn, R A

    1996-01-01

    With unlimited money the most certain strategy for finding most hydrothermal metal deposits would be by drilling to 5000 m at 50 m spacing. However, the cost would far outweigh the benefit of the discoveries. Geological knowledge and exploration techniques may be used to obtain the greatest benefit for minimum cost, and to concentrate human and material resources in the most economic way in areas with the highest probability of discovery. This paper reviews the economic theory of exploration based on expected value, and the application of geological concepts and exploration techniques to exploration for hydrothermal deposits. Exploration techniques for hydrothermal-systems on Mars would include geochemistry and particularly passive geophysical methods.

  9. Strategies to Combat Antimicrobial Resistance

    PubMed Central

    Uchil, Rajesh R; Kohli, Gurdeep Singh; Katekhaye, Vijay M

    2014-01-01

    The global burden of antimicrobial resistance is rising and is associated with increased morbidity and mortality in clinical and community setting. Spread of antibiotic resistance to different environmental niches and development of superbugs have further complicated the effective control strategies. International, national and local approaches have been advised for control and prevention of antimicrobial resistance. Rational use of antimicrobials, regulation on over-the-counter availability of antibiotics, improving hand hygiene and improving infection prevention and control are the major recommended approaches. Thorough understanding of resistance mechanism and innovation in new drugs and vaccines is the need. A multidisciplinary, collaborative, regulatory approach is demanded for combating antimicrobial resistance. PMID:25177596

  10. Immunocapture strategies in translational proteomics

    PubMed Central

    Fredolini, Claudia; Byström, Sanna; Pin, Elisa; Edfors, Fredrik; Tamburro, Davide; Iglesias, Maria Jesus; Häggmark, Anna; Hong, Mun-Gwan; Uhlen, Mathias; Nilsson, Peter; Schwenk, Jochen M

    2016-01-01

    Aiming at clinical studies of human diseases, antibody-assisted assays have been applied to biomarker discovery and toward a streamlined translation from patient profiling to assays supporting personalized treatments. In recent years, integrated strategies to couple and combine antibodies with mass spectrometry-based proteomic efforts have emerged, allowing for novel possibilities in basic and clinical research. Described in this review are some of the field’s current and emerging immunocapture approaches from an affinity proteomics perspective. Discussed are some of their advantages, pitfalls and opportunities for the next phase in clinical and translational proteomics. PMID:26558424

  11. Neuroprotective strategies in radical prostatectomy.

    PubMed

    Schiff, Jonathan D; Mulhall, John P

    2005-01-01

    In this section, authors from New York give their views on the various neuroprotective strategies for patients having a radical prostatectomy, such as the use of nerve grafts and other approaches. A joint study from Korea, the USA, Canada and the UK is presented in a paper on the importance of patient perception in the clinical assessment and management of BPH. There is also a review of robotic urological surgery. Finally, authors from New York give a review on the life of Isaac Newton. This is a new historical review in the journal, but one that will be of general interest.

  12. Mars Odyssey interplanetary navigation strategy

    NASA Technical Reports Server (NTRS)

    Mase, Robert A.; Antreasian, Peter G.; Bell, Julia L.

    2003-01-01

    The 2001 Mars Odyssey Mission has returned an orbiter to map the planet and search for water. The success of this mission has reestablished confidence in Mars exploration that will pave the way for future orbiters, landers, adn rovers. The spacecraft has completed its journey and is now in the orbital science-gathering phase of the primary mission, which will continue through August 2004. This paper will describe teh strategy that was designed to safely and accurately navigate the spacecraft to Mars, and also relate the in-flight experience.

  13. Adaptive strategy for joint measurements

    NASA Astrophysics Data System (ADS)

    Uola, Roope; Luoma, Kimmo; Moroder, Tobias; Heinosaari, Teiko

    2016-08-01

    We develop a technique to find simultaneous measurements for noisy quantum observables in finite-dimensional Hilbert spaces. We use the method to derive lower bounds for the noise needed to make incompatible measurements jointly measurable. Using our strategy together with recent developments in the field of one-sided quantum information processing we show that the attained lower bounds are tight for various symmetric sets of quantum measurements. We use this characterisation to prove the existence of so called 4-Specker sets, i.e. sets of four incompatible observables with compatible subsets in the qubit case.

  14. Strategies for treatment of dystonia.

    PubMed

    Dressler, Dirk; Altenmueller, Eckart; Bhidayasiri, Roongroj; Bohlega, Saeed; Chana, Pedro; Chung, Tae Mo; Frucht, Steven; Garcia-Ruiz, Pedro J; Kaelin, Alain; Kaji, Ryuji; Kanovsky, Petr; Laskawi, Rainer; Micheli, Federico; Orlova, Olga; Relja, Maja; Rosales, Raymond; Slawek, Jaroslaw; Timerbaeva, Sofia; Warner, Thomas T; Saberi, Fereshte Adib

    2016-03-01

    Treatment of dystonias is generally symptomatic. To produce sufficient therapy effects, therefore, frequently a multimodal and interdisciplinary therapeutic approach becomes necessary, combining botulinum toxin therapy, deep brain stimulation, oral antidystonic drugs, adjuvant drugs and rehabilitation therapy including physiotherapy, occupational therapy, re-training, speech therapy, psychotherapy and sociotherapy. This review presents the recommendations of the IAB-Interdisciplinary Working Group for Movement Disorders Special Task Force on Interdisciplinary Treatment of Dystonia. It reviews the different therapeutic modalities and outlines a strategy to adapt them to the dystonia localisation and severity of the individual patient. Hints to emerging and future therapies will be given. PMID:26370676

  15. Parking: an effective strategy described.

    PubMed

    Herring, Philip

    2013-11-01

    A hospital car park needs to balance the demands of patients, visitors, and staff, without, for example, compromising emergency vehicles' access to the Accident & Emergency Department. However, with car ownership on the rise, the half a million car parking spaces across all Trust sites in England may not be enough to meet future demand. Philip Herring, managing director of VINCI Park UK, which designs, finances, builds, and operates, car parks for a variety of sectors, argues that having in place an effective strategy for future parking is vital to meet the growing needs of patients, visitors, and staff, as well as budgetary and environmental commitments.

  16. Strategy for outer planets exploration

    NASA Technical Reports Server (NTRS)

    1975-01-01

    NASA's Planetary Programs Office formed a number of scientific working groups to study in depth the potential scientific return from the various candidate missions to the outer solar system. The results of these working group studies were brought together in a series of symposia to evaluate the potential outer planet missions and to discuss strategies for exploration of the outer solar system that were consistent with fiscal constraints and with anticipated spacecraft and launch vehicle capabilities. A logical, scientifically sound, and cost effective approach to exploration of the outer solar system is presented.

  17. Computer conferencing: Choices and strategies

    NASA Technical Reports Server (NTRS)

    Smith, Jill Y.

    1991-01-01

    Computer conferencing permits meeting through the computer while sharing a common file. The primary advantages of computer conferencing are that participants may (1) meet simultaneously or nonsimultaneously, and (2) contribute across geographic distance and time zones. Due to these features, computer conferencing offers a viable meeting option for distributed business teams. Past research and practice is summarized denoting practical uses of computer conferencing as well as types of meeting activities ill suited to the medium. Additionally, effective team strategies are outlined which maximize the benefits of computer conferencing.

  18. Osteoporosis: Prevention and Management Strategies

    PubMed Central

    Evers, Susan; Myers, Anita

    1987-01-01

    Osteoporosis is a major cause of morbidity in post-menopausal women. Strategies to prevent or delay bone loss in normal post-menopausal women and to reduce the risk of fractures in women with osteoporosis are within the scope of family practice. Certain factors, such as inadequate calcium intake, estrogen deficiency, cigarette smoking and lack of physical activity can be modified in peri- and post-menopausal women. For patients with osteoporosis, there is potential for lowering the risk of fractures by means of calcium supplements or other therapies, physical training and rehabilitation, and modification of factors associated with risk of falling. PMID:21267348

  19. Health promotion and prevention strategies.

    PubMed

    Bradbury-Golas, Kathleen

    2013-09-01

    Opiate dependency is a medical disorder that requires treatment intervention. Primary health care not only entails treatment of illness but also involves disease prevention and health promotion. Based on Pender's revised Health Promotion Model, a descriptive study comparing the health promoting behaviors/practices in abusing and recovering opiate-dependent drug users is analyzed. Using the Health Promoting Lifestyle Profile II, a comparative descriptive, exploratory, nonexperimental design study was conducted to identify key health-promoting behaviors in recovering opiate-dependent drug users. Prevention strategy recommendations are discussed, along with future research recommendations.

  20. A Phytoremediation Strategy for Arsenic

    SciTech Connect

    Meagher, Richard B.

    2005-06-01

    A Phytoremediation Strategy for Arsenic Progress Report May, 2005 Richard B. Meagher Principal Investigator Arsenic pollution affects the health of several hundred millions of people world wide, and an estimated 10 million Americans have unsafe levels of arsenic in their drinking water. However, few environmentally sound remedies for cleaning up arsenic contaminated soil and water have been proposed. Phytoremediation, the use of plants to extract and sequester environmental pollutants, is one new technology that offers an ecologically sound solution to a devastating problem. We propose that it is less disruptive to the environment to harvest and dispose of several thousand pounds per acre of contaminated aboveground plant material, than to excavate and dispose of 1 to 5 million pounds of contaminated soil per acre (assumes contamination runs 3 ft deep). Our objective is to develop a genetics-based phytoremediation strategy for arsenic removal that can be used in any plant species. This strategy requires the enhanced expression of several transgenes from diverse sources. Our working hypothesis is that organ-specific expression of several genes controlling the transport, electrochemical state, and binding of arsenic will result in the efficient extraction and hyperaccumulation of arsenic into aboveground plant tissues. This hypothesis is supported by theoretical arguments and strong preliminary data. We proposed six Specific Aims focused on testing and developing this arsenic phytoremediation strategy. During the first 18 months of the grant we made significant progress on five Specific Aims and began work on the sixth as summarized below. Specific Aim 1: Enhance plant arsenic resistance and greatly expand sinks for arsenite by expressing elevated levels of thiol-rich, arsenic-binding peptides. Hyperaccumulation of arsenic depends upon making plants that are both highly tolerant to arsenic and that have the capacity to store large amounts of arsenic aboveground

  1. Prodrug strategies in anticancer chemotherapy.

    PubMed

    Kratz, Felix; Müller, Ivonne A; Ryppa, Claudia; Warnecke, André

    2008-01-01

    The majority of clinically approved anticancer drugs are characterized by a narrow therapeutic window that results mainly from a high systemic toxicity of the drugs in combination with an evident lack of tumor selectivity. Besides the development of suitable galenic formulations such as liposomes or micelles, several promising prodrug approaches have been followed in the last decades with the aim of improving chemotherapy. In this review we elucidate the two main concepts that underlie the design of most anticancer prodrugs: drug targeting and controlled release of the drug at the tumor site. Consequently, active and passive targeting using tumor-specific ligands or macromolecular carriers are discussed as well as release strategies that are based on tumor-specific characteristics such as low pH or the expression of tumor-associated enzymes. Furthermore, other strategies such as ADEPT (antibody-directed enzyme prodrug therapy) and the design of self-eliminating structures are introduced. Chemical realization of prodrug approaches is illustrated by drug candidates that have or may have clinical importance.

  2. Strategy Guideline: HVAC Equipment Sizing

    SciTech Connect

    Burdick, A.

    2012-02-01

    The heating, ventilation, and air conditioning (HVAC) system is arguably the most complex system installed in a house and is a substantial component of the total house energy use. A right-sized HVAC system will provide the desired occupant comfort and will run efficiently. This Strategy Guideline discusses the information needed to initially select the equipment for a properly designed HVAC system. Right-sizing of an HVAC system involves the selection of equipment and the design of the air distribution system to meet the accurate predicted heating and cooling loads of the house. Right-sizing the HVAC system begins with an accurate understanding of the heating and cooling loads on a space; however, a full HVAC design involves more than just the load estimate calculation - the load calculation is the first step of the iterative HVAC design procedure. This guide describes the equipment selection of a split system air conditioner and furnace for an example house in Chicago, IL as well as a heat pump system for an example house in Orlando, Florida. The required heating and cooling load information for the two example houses was developed in the Department of Energy Building America Strategy Guideline: Accurate Heating and Cooling Load Calculations.

  3. Interventional strategies in early atherosclerosis.

    PubMed

    Gattone, Marinella; Giannuzzi, Pantaleo

    2006-03-01

    Atherosclerosis remains clinically mute for a long time and frequently manifests itself with an acute cardiovascular event; therefore, the possibility to detect the disease in a subclinical phase and to reduce or reverse its progression is an issue of relevance. Non-invasive diagnostic procedures such as B-mode ultrasonography of carotid intima-media thickness (CIMT), electron beam computed tomography (EBCT) and magnetic resonance angiography (MRA) allow to identify atherosclerotic disease in its early phases, to evaluate the disease progression and monitor the effects of interventions. In recent years, several therapeutic strategies have been adopted over time to slow early atherosclerosis in asymptomatic individuals at intermediate/high cardiovascular risk. Prospective trials employing multifactorial non-pharmacological interventions (diet, exercise, smoking cessation) have demonstrated a favorable effect on progression of atherosclerosis. Hence lifestyle modification may be an effective therapeutic strategy to be adopted as a first step and a highly cost-effective intervention in a preclinical setting involving a large number of individuals. Drugs should be considered as a second step or should be associated to further reduce the risk in individuals at high probability of future events, who require more intensive interventions. Reducing low-density lipoprotein levels, blood pressure and platelet aggregation seems to be the most effective intervention in these subjects, whereas the treatment of emerging coronary risk factors, e.g. oxidative stress, inflammatory activation and infections has not produced the expected protective effect. PMID:17125046

  4. Interplay of approximate planning strategies

    PubMed Central

    Huys, Quentin J. M.; Lally, Níall; Faulkner, Paul; Eshel, Neir; Seifritz, Erich; Gershman, Samuel J.; Dayan, Peter; Roiser, Jonathan P.

    2015-01-01

    Humans routinely formulate plans in domains so complex that even the most powerful computers are taxed. To do so, they seem to avail themselves of many strategies and heuristics that efficiently simplify, approximate, and hierarchically decompose hard tasks into simpler subtasks. Theoretical and cognitive research has revealed several such strategies; however, little is known about their establishment, interaction, and efficiency. Here, we use model-based behavioral analysis to provide a detailed examination of the performance of human subjects in a moderately deep planning task. We find that subjects exploit the structure of the domain to establish subgoals in a way that achieves a nearly maximal reduction in the cost of computing values of choices, but then combine partial searches with greedy local steps to solve subtasks, and maladaptively prune the decision trees of subtasks in a reflexive manner upon encountering salient losses. Subjects come idiosyncratically to favor particular sequences of actions to achieve subgoals, creating novel complex actions or “options.” PMID:25675480

  5. Strategies to Reduce Hospital Readmissions.

    PubMed

    Chirapongsathorn, Sakkarin; Talwalkar, Jayant A; Kamath, Patrick S

    2016-05-01

    After the Patient Protection and Affordable Care Act or "Obamacare" was signed into law in 2010, the problem of readmission has taken on a new sense of urgency. Hospitals with excess readmissions receive reduced reimbursement because readmission is considered to represent a poor quality measure in the healthcare delivery system. Cirrhosis places a major burden on the healthcare economy. Patients with cirrhosis frequently require hospitalization, and annual admission rates have doubled within 10 years. The costs of hospitalization associated with cirrhosis have also markedly increased. Readmissions create negative consequences for the patient and the family. Several strategies have been proposed to reduce the number of readmissions, but the efficacy of these strategies is questionable. Although the Model for End-Stage of Liver Disease (MELD) score can be a tool for risk stratification, many other factors are also independent risks for readmission. Studies aimed at the reduction of readmission in patients with cirrhosis are very limited, and much research is required before specific recommendations can be made to reduce readmissions.

  6. Perioperative anti-endotoxin strategies.

    PubMed

    Houdijk, A P; Meijer, C; Cuesta, M A; Meyer, S; Van Leeuwen, P A

    1997-01-01

    Lipopolysaccharides from the outer membrane of Gram-negative bacteria are potent stimuli for the production of numerous cytokines by the immune cells. The systemic inflammatory response to these gut-derived endotoxins is therefore dependent on the responsiveness of the immune system. This paper presents results on anti-endotoxin strategies and the responsiveness to endotoxin in animal models of liver failure. Following partial hepatectomy in the normal rat, anti-endotoxin treatment using the enteral endotoxin binder cholestyramine and the bactericidal permeability-increasing protein showed beneficial effects in terms of reducing the exaggerated metabolic and inflammatory responses. Similar beneficial effects of gut endotoxin restriction were found in bile duct ligated rats subjected to a laparotomy. The beneficial effects of anti-endotoxin strategies in these models were explained by completely different mechanisms. In partial hepatectomized rats the effects were explained by the direct inhibition of the stimulatory action of endotoxin on immune cells preventing an exaggerated inflammatory response. In contrast, in postoperative BDL rats the effects of anti-endotoxin therapy were explained by the restoration of endotoxin sensitivity of the immune cells resulting in an inflammatory response necessary for an adequate reaction to surgery. These different mechanism will be discussed in the light of the phenomenon of endotoxin tolerance.

  7. Optimization of BEV Charging Strategy

    NASA Astrophysics Data System (ADS)

    Ji, Wei

    This paper presents different approaches to optimize fast charging and workplace charging strategy of battery electric vehicle (BEV) drivers. For the fast charging analysis, a rule-based model was built to simulate BEV charging behavior. Monte Carlo analysis was performed to explore to the potential range of congestion at fast charging stations which could be more than four hours at the most crowded stations. Genetic algorithm was performed to explore the theoretical minimum waiting time at fast charging stations, and it can decrease the waiting time at the most crowded stations to be shorter than one hour. A deterministic approach was proposed as a feasible suggestion that people should consider to take fast charging when the state of charge is approaching 40 miles. This suggestion is hoped to help to minimize potential congestion at fast charging stations. For the workplace charging analysis, scenario analysis was performed to simulate temporal distribution of charging demand under different workplace charging strategies. It was found that if BEV drivers charge as much as possible and as late as possible at workplace, it could increase the utility of solar-generated electricity while relieve grid stress of extra intensive electricity demand at night caused by charging electric vehicles at home.

  8. AGING SYSTEM DESIGN DEVELOPMENT STRATEGY

    SciTech Connect

    J. Beesley

    2005-02-07

    This plan provides an overview, work to date, and the path forward for the design development strategy of the Aging cask for aging commercial spent nuclear fuel (CSNF) at the Yucca Mountain Project (YMP) repository site. Waste for subsurface emplacement at the repository includes US Department of Energy (DOE) high-level radioactive waste (HLW), DOE SNF, commercial fuel in dual-purpose canisters (DPCs), uncanistered bare fuel, naval fuel, and other waste types. Table 1-1 lists the types of radioactive materials that may be aged at YMP, and those materials that will not be placed in an aging cask or module. This plan presents the strategy for design development of the Aging system. The Aging system will not handle naval fuel, DOE HLW, MCOs, or DOE SNF since those materials will be delivered to the repository in a state and sequence that allows them to be placed into waste packages for emplacement. Some CSNF from nuclear reactors, especially CSNF that is thermally too hot for emplacement underground, will need to be aged at the repository.

  9. Improving containment strategies in biopharming.

    PubMed

    Murphy, Denis J

    2007-09-01

    This review examines the challenges of segregating biopharmed crops expressing pharmaceutical or veterinary agents from mainstream crops, particularly those destined for food or feed use. The strategy of using major food crops as production vehicles for the expression of pharmaceutical or veterinary agents is critically analysed in the light of several recent episodes of contamination of the human food chain by non-approved crop varieties. Commercially viable strategies to limit or avoid biopharming intrusion into the human food chain require the more rigorous segregation of food and non-food varieties of the same crop species via a range of either physical or biological methods. Even more secure segregation is possible by the use of non-food crops, non-crop plants or in vitro plant cultures as production platforms for biopharming. Such platforms already under development range from outdoor-grown Nicotiana spp. to glasshouse-grown Arabidopsis, lotus and moss. Amongst the more effective methods for biocontainment are the plastid expression of transgenes, inducible and transient expression systems, and physical containment of plants or cell cultures. In the current atmosphere of heightened concerns over food safety and biosecurity, the future of biopharming may be largely determined by the extent to which the sector is able to maintain public confidence via a more considered approach to containment and security of its plant production systems.

  10. Commitment strategies in hierarchical task network planning

    SciTech Connect

    Tsuneto, R.; Hendler, J.; Nau, D.; Erol, K.

    1996-12-31

    This paper compares three commitment strategies for HTN planning: (1) a strategy that delays variable bindings as much as possible; (2) a strategy in which no non-primitive task is expanded until all variable constraints are committed; and (3) a strategy that chooses between expansion and variable instantiation based on the number of branches that will be created in the search tree. Our results show that while there exist planning domains in which the first two strategies do well, the third does well over a broader range of planning domains.

  11. Investigation the Relationship among Language Learning Strategies, English Self-Efficacy, and Explicit Strategy Instructions

    ERIC Educational Resources Information Center

    Yang, Pei-Ling; Wang, Ai-Ling

    2015-01-01

    The present study aims to investigate the relationship among EFL college learners' language learning strategies, English self-efficacy, and explicit strategy instruction from the perspectives of Social Cognitive Theory. Three constructs, namely language learning strategies, English learning self-efficacy, and explicit strategy instruction, were…

  12. Working Memory, Strategy Knowledge, and Strategy Instruction in Children with Reading Disabilities

    ERIC Educational Resources Information Center

    Swanson, H. Lee; Kehler, Pam; Jerman, Olga

    2010-01-01

    Two experiments investigated the effects of strategy knowledge and strategy training on the working memory (WM) performance in children (ages 10-11) with and without reading disabilities (RD). Experiment 1 examined the relationship between strategy knowledge (stability of strategy choices) and WM performance as a function of initial, gain (cued),…

  13. A suicide prevention strategy for England.

    PubMed

    Mehlum, Lars

    2004-01-01

    Over the last decade an increasing number of countries have established national strategies for suicide prevention. In the autumn of 2002 the suicide prevention strategy for England was presented to the general public, introducing what could be called a second generation of national programs for suicide prevention. This strategy uses evidence-based criteria for its priorities more systematically than before. Furthermore, it has put an increased emphasis on goals being specific, preventive measures being practical, and the preventive potential being visible. Other guiding principles for this strategy are that suicide preventive measures and initiatives should be open to monitoring and evaluation, and that revisions and updates of the national strategy should be made regularly--thus constituting an evolving strategy. This paper examines the content of the new national strategy for suicide prevention in England and what new contributions to the field it may make.

  14. Antiviral Strategies Against Chikungunya Virus.

    PubMed

    Abdelnabi, Rana; Neyts, Johan; Delang, Leen

    2016-01-01

    In the last few decades the Chikungunya virus (CHIKV) has evolved from a geographically isolated pathogen to a virus that is widespread in many parts of Africa, Asia and recently also in Central- and South-America. Although CHIKV infections are rarely fatal, the disease can evolve into a chronic stage, which is characterized by persisting polyarthralgia and joint stiffness. This chronic CHIKV infection can severely incapacitate patients for weeks up to several years after the initial infection. Despite the burden of CHIKV infections, no vaccine or antivirals are available yet. The current therapy is therefore only symptomatic and consists of the administration of analgesics, antipyretics, and anti-inflammatory agents. Recently several molecules with various viral or host targets have been identified as CHIKV inhibitors. In this chapter, we summarize the current status of the development of antiviral strategies against CHIKV infections.

  15. Treatment strategy for Boerhaave's syndrome.

    PubMed

    Ochiai, T; Hiranuma, S; Takiguchi, N; Ito, K; Maruyama, M; Nagahama, T; Kawano, T; Nagai, K; Nishikage, T; Noguchi, N; Takamatsu, S; Kawamura, T; Teramoto, K; Iwai, T; Arii, S

    2004-01-01

    Esophageal rupture is a potentially mortal condition. Rapid and correct diagnosis, and urgent surgical treatment with esophagectomy is indicated, but conservative and other surgical treatments have also been reported recently. The treatment strategies for esophageal rupture are discussed here, based on our experiences with four cases during the last 10 years. They were admitted urgently and each was treated by a different method. Three of them underwent emergency operations, one undergoing primary closure of the ruptured esophagus, another received a T-tube insertion from the ruptured site with omental flap, and the third an esophagogastrectomy. The fourth case was treated conservatively. All patients survived and were discharged 36-144 days post treatment. One of them was readmitted for debridement of necrotic rib. In conclusion, the prompt and accurate diagnosis of esophageal rupture is crucial for a subsequent successful treatment. Conservative treatment or operation including esophagectomy will be determined by the severity of the condition.

  16. Successful strategies for competing networks

    NASA Astrophysics Data System (ADS)

    Aguirre, J.; Papo, D.; Buldú, J. M.

    2013-04-01

    Competitive interactions represent one of the driving forces behind evolution and natural selection in biological and sociological systems. For example, animals in an ecosystem may vie for food or mates; in a market economy, firms may compete over the same group of customers; sensory stimuli may compete for limited neural resources to enter the focus of attention. Here, we derive rules based on the spectral properties of the network governing the competitive interactions between groups of agents organized in networks. In the scenario studied here the winner of the competition, and the time needed to prevail, essentially depend on the way a given network connects to its competitors and on its internal structure. Our results allow assessment of the extent to which real networks optimize the outcome of their interaction, but also provide strategies through which competing networks can improve on their situation. The proposed approach is applicable to a wide range of systems that can be modelled as networks.

  17. Security solutions: strategy and architecture

    NASA Astrophysics Data System (ADS)

    Seto, Myron W. L.

    2002-04-01

    Producers of banknotes, other documents of value and brand name goods are being presented constantly with new challenges due to the ever increasing sophistication of easily-accessible desktop publishing and color copying machines, which can be used for counterfeiting. Large crime syndicates have also shown that they have the means and the willingness to invest large sums of money to mimic security features. To ensure sufficient and appropriate protection, a coherent security strategy has to be put into place. The feature has to be appropriately geared to fight against the different types of attacks and attackers, and to have the right degree of sophistication or ease of authentication depending upon by whom or where a check is made. Furthermore, the degree of protection can be considerably increased by taking a multi-layered approach and using an open platform architecture. Features can be stratified to encompass overt, semi-covert, covert and forensic features.

  18. [Therapeutic strategies against myasthenia gravis].

    PubMed

    Utsugisawa, Kimiaki; Nagane, Yuriko

    2013-05-01

    Many patients with myasthenia gravis (MG) still find it difficult to maintain daily activities due to chronic residual fatigability and long-term side effects of oral corticosteroids, since full remission is not common. Our analysis demonstrated that disease severity, oral corticosteroids, and depressive state are the major factors negatively associated with QOL, and that QOL of MM status patients taking < or = 5 mg prednisolne/day is identically good as that seen in CSR and is a target of treatment. In order to achieve early MM or better status with prednisolne < or = 5 mg/day, we advocate the early aggressive treatment strategy that can achieve early improvement by performing an aggressive therapy using combined treatment with plasmapheresis and high-dose intravenous methylprednisolone and then maintain an improved status using low-dose oral corticosteroids and calcineurin inhibitors. PMID:23777099

  19. Strategies to Minimize Antibiotic Resistance

    PubMed Central

    Lee, Chang-Ro; Cho, Ill Hwan; Jeong, Byeong Chul; Lee, Sang Hee

    2013-01-01

    Antibiotic resistance can be reduced by using antibiotics prudently based on guidelines of antimicrobial stewardship programs (ASPs) and various data such as pharmacokinetic (PK) and pharmacodynamic (PD) properties of antibiotics, diagnostic testing, antimicrobial susceptibility testing (AST), clinical response, and effects on the microbiota, as well as by new antibiotic developments. The controlled use of antibiotics in food animals is another cornerstone among efforts to reduce antibiotic resistance. All major resistance-control strategies recommend education for patients, children (e.g., through schools and day care), the public, and relevant healthcare professionals (e.g., primary-care physicians, pharmacists, and medical students) regarding unique features of bacterial infections and antibiotics, prudent antibiotic prescribing as a positive construct, and personal hygiene (e.g., handwashing). The problem of antibiotic resistance can be minimized only by concerted efforts of all members of society for ensuring the continued efficiency of antibiotics. PMID:24036486

  20. Control strategies for a telerobot

    NASA Technical Reports Server (NTRS)

    Ohara, John; Stasi, Bill

    1989-01-01

    One of the major issues impacting the utility of telerobotic systems for space is the development of effective control strategies. For near-term applications, telerobot control is likely to utilize teleoperation methodologies with integrated supervisory control capabilities to assist the operator. Two different approaches to telerobotic control are evaluated: bilateral force reflecting master controllers and proportional rate six degrees-of-freedom hand controllers. The controllers' performance of single manipulator arm tasks is compared. Simultaneous operation of both manipulator arms and complex multiaxis slave arm movements is investigated. Task times are significantly longer and fewer errors are committed with the hand controllers. The hand controllers are also rated significantly higher in cognitive and manual control workload on the two-arm task. The master controllers are rated significantly higher in physical workload. The implications of these findings for space teleoperations and higher levels of control are discussed.

  1. Treatment strategy for Boerhaave's syndrome.

    PubMed

    Ochiai, T; Hiranuma, S; Takiguchi, N; Ito, K; Maruyama, M; Nagahama, T; Kawano, T; Nagai, K; Nishikage, T; Noguchi, N; Takamatsu, S; Kawamura, T; Teramoto, K; Iwai, T; Arii, S

    2004-01-01

    Esophageal rupture is a potentially mortal condition. Rapid and correct diagnosis, and urgent surgical treatment with esophagectomy is indicated, but conservative and other surgical treatments have also been reported recently. The treatment strategies for esophageal rupture are discussed here, based on our experiences with four cases during the last 10 years. They were admitted urgently and each was treated by a different method. Three of them underwent emergency operations, one undergoing primary closure of the ruptured esophagus, another received a T-tube insertion from the ruptured site with omental flap, and the third an esophagogastrectomy. The fourth case was treated conservatively. All patients survived and were discharged 36-144 days post treatment. One of them was readmitted for debridement of necrotic rib. In conclusion, the prompt and accurate diagnosis of esophageal rupture is crucial for a subsequent successful treatment. Conservative treatment or operation including esophagectomy will be determined by the severity of the condition. PMID:15209751

  2. Antiviral Strategies Against Chikungunya Virus.

    PubMed

    Abdelnabi, Rana; Neyts, Johan; Delang, Leen

    2016-01-01

    In the last few decades the Chikungunya virus (CHIKV) has evolved from a geographically isolated pathogen to a virus that is widespread in many parts of Africa, Asia and recently also in Central- and South-America. Although CHIKV infections are rarely fatal, the disease can evolve into a chronic stage, which is characterized by persisting polyarthralgia and joint stiffness. This chronic CHIKV infection can severely incapacitate patients for weeks up to several years after the initial infection. Despite the burden of CHIKV infections, no vaccine or antivirals are available yet. The current therapy is therefore only symptomatic and consists of the administration of analgesics, antipyretics, and anti-inflammatory agents. Recently several molecules with various viral or host targets have been identified as CHIKV inhibitors. In this chapter, we summarize the current status of the development of antiviral strategies against CHIKV infections. PMID:27233277

  3. Targeted Strategies for Henipavirus Therapeutics

    PubMed Central

    Bossart, Katharine N; Bingham, John; Middleton, Deborah

    2007-01-01

    Hendra and Nipah viruses are related emergent paramyxoviruses that infect and cause disease in animals and humans. Disease manifests as a generalized vasculitis affecting multiple organs, but is the most severe in the respiratory and central nervous systems. The high case fatality and person-to-person transmission associated with the most recent NiV outbreaks, and the recent re-emergence of HeV, emphasize the importance and necessity of effective therapeutics for these novel agents. In recent years henipavirus research has revealed a more complete understanding of pathogenesis and, as a consequence, viable approaches towards vaccines and therapeutics have emerged. All strategies target early steps in viral replication including receptor binding and membrane fusion. Animal models have been developed, some of which may prove more valuable than others for evaluating the efficacy of therapeutic agents and regimes. Assessments of protective host immunity and drug pharmacokinetics will be crucial to the further advancement of therapeutic compounds. PMID:19440455

  4. Optimal intervention strategies for tuberculosis

    NASA Astrophysics Data System (ADS)

    Bowong, Samuel; Aziz Alaoui, A. M.

    2013-06-01

    This paper deals with the problem of optimal control of a deterministic model of tuberculosis (abbreviated as TB for tubercle bacillus). We first present and analyze an uncontrolled tuberculosis model which incorporates the essential biological and epidemiological features of the disease. The model is shown to exhibit the phenomenon of backward bifurcation, where a stable disease-free equilibrium co-exists with one or more stable endemic equilibria when the associated basic reproduction number is less than the unity. Based on this continuous model, the tuberculosis control is formulated and solved as an optimal control problem, indicating how control terms on the chemoprophylaxis and detection should be introduced in the population to reduce the number of individuals with active TB. Results provide a framework for designing the cost-effective strategies for TB with two intervention methods.

  5. Nuclear arms: ethics, strategy, politics

    SciTech Connect

    Woolsey, R.J.

    1984-01-01

    The range of debate over strategy and arms control today is broader than it was in the late 1950s and early 1960s. In part this is because the early 1980s debate has involved questioning of the fundamental notion of deterrence - by no less than the American Catholic bishops. Today's debate has also seen a national nuclear freeze campaign that, although its congressional supporters have held firmly to a bilateral approach, was tilted perceptibly towards unilateralism by noncongressional leaders at their national conference in February 1983. In one way or another the authors wrestle with different aspects of one central question: could the beginning steps for any consensus be possible, in today's climate, on strategic issues. Ethical issues are addressed in the first 3 papers: Charles Krauthammer, On Nuclear Morality; Patrick Glynn, The Moral Case for the Arms Buildup; and Michael Quinlarc, Thinking Deterrence Through. Three chapters on strategic considerations include: Brent Snowcroft, Understanding the US Strategic Arsenal; William J. Perry, Technological Prospects for US Strategic Forces; and Richard Burt, The Strategic and Political Lessons of INF. Arms control and politics is treated in chapters by: Walter B. Slocombe, Arms Control: Prospects; and Colin S. Gray, Arms Control: Problems. The nonnuclear dimensions of strategy are discussed in chapters by Amory B. and L. Hunter Lovins, Reducing Vulnerability - The Energy Jugular; and Robert Kupperman, Vulnerable America. The chapters on space and defense are: Hans Mark, Arms Control and Space Technology; and Newt Gingrich and John Madison, Space and National Defense. The concluding chapters are by Sen. Sam Nunn, The Need to Reshape Military Stategy; and the editor, R. James Woolsey, The Politics of Vulnerability, 1980-1983.

  6. Big Data - Smart Health Strategies

    PubMed Central

    2014-01-01

    Summary Objectives To select best papers published in 2013 in the field of big data and smart health strategies, and summarize outstanding research efforts. Methods A systematic search was performed using two major bibliographic databases for relevant journal papers. The references obtained were reviewed in a two-stage process, starting with a blinded review performed by the two section editors, and followed by a peer review process operated by external reviewers recognized as experts in the field. Results The complete review process selected four best papers, illustrating various aspects of the special theme, among them: (a) using large volumes of unstructured data and, specifically, clinical notes from Electronic Health Records (EHRs) for pharmacovigilance; (b) knowledge discovery via querying large volumes of complex (both structured and unstructured) biological data using big data technologies and relevant tools; (c) methodologies for applying cloud computing and big data technologies in the field of genomics, and (d) system architectures enabling high-performance access to and processing of large datasets extracted from EHRs. Conclusions The potential of big data in biomedicine has been pinpointed in various viewpoint papers and editorials. The review of current scientific literature illustrated a variety of interesting methods and applications in the field, but still the promises exceed the current outcomes. As we are getting closer towards a solid foundation with respect to common understanding of relevant concepts and technical aspects, and the use of standardized technologies and tools, we can anticipate to reach the potential that big data offer for personalized medicine and smart health strategies in the near future. PMID:25123721

  7. Novel Therapeutic Strategies for Dementia.

    PubMed

    Cacabelos, Ramón; Torrellas, Clara; Carrera, Iván; Cacabelos, Pablo; Corzo, Lola; Fernández-Novoa, Lucía; Tellado, Iván; Carril, Juan C; Aliev, Gjumrakch

    2016-01-01

    Dementia represents a major problem of health and disability, with a relevant economic impact on our society. Despite important advances in pathogenesis, diagnosis and treatment, its primary causes still remain elusive, accurate biomarkers are not well characterized, and the available pharmacological treatments are not cost-effective. Alzheimer disease (AD), the most prevalent form of dementia, is a polygenic/multifactorial/complex disorder in which hundreds of defective genes distributed across the human genome may contribute to its pathogenesis. Diverse environmental factors, cerebrovascular dysfunction, and epigenetic phenomena, together with structural and functional genomic dysfunctions lead to amyloid deposition, neurofibrillary tangle formation and premature neuronal death, the major neuropathological hallmarks of AD. For the past 20 years, over 1,000 different compounds have been studied as potential candidate drugs for the treatment of AD. About 50% of these substances are novel molecules obtained from natural sources. The candidate compounds can be classified according to their pharmacological properties and/or the AD-related pathogenic cascade to which they are addressed to halt disease progression. In addition to the Food and Drug Administration (FDA)-approved drugs since 1993 (tacrine, donepezil, rivastigmine, galantamine, memantine), most candidate strategies fall into 6 major categories: (i) novel cholinesterase inhibitors and neurotransmitter regulators, (ii) anti-amyloid beta (Aβ) treatments (amyloid-β protein precursor (APP) regulators, Aβ breakers, active and passive immunotherapy with vaccines and antibodies, β - and γ - secretase inhibitors or modulators), (iii) anti-tau treatments, (iv) pleiotropic products (most of them of natural origin), (v) epigenetic intervention, and (vi) combination therapies. The implementation of pharmacogenomic strategies will contribute to optimize drug development and therapeutics in AD and related disorders.

  8. Novel Therapeutic Strategies for Dementia.

    PubMed

    Cacabelos, Ramón; Torrellas, Clara; Carrera, Iván; Cacabelos, Pablo; Corzo, Lola; Fernández-Novoa, Lucía; Tellado, Iván; Carril, Juan C; Aliev, Gjumrakch

    2016-01-01

    Dementia represents a major problem of health and disability, with a relevant economic impact on our society. Despite important advances in pathogenesis, diagnosis and treatment, its primary causes still remain elusive, accurate biomarkers are not well characterized, and the available pharmacological treatments are not cost-effective. Alzheimer disease (AD), the most prevalent form of dementia, is a polygenic/multifactorial/complex disorder in which hundreds of defective genes distributed across the human genome may contribute to its pathogenesis. Diverse environmental factors, cerebrovascular dysfunction, and epigenetic phenomena, together with structural and functional genomic dysfunctions lead to amyloid deposition, neurofibrillary tangle formation and premature neuronal death, the major neuropathological hallmarks of AD. For the past 20 years, over 1,000 different compounds have been studied as potential candidate drugs for the treatment of AD. About 50% of these substances are novel molecules obtained from natural sources. The candidate compounds can be classified according to their pharmacological properties and/or the AD-related pathogenic cascade to which they are addressed to halt disease progression. In addition to the Food and Drug Administration (FDA)-approved drugs since 1993 (tacrine, donepezil, rivastigmine, galantamine, memantine), most candidate strategies fall into 6 major categories: (i) novel cholinesterase inhibitors and neurotransmitter regulators, (ii) anti-amyloid beta (Aβ) treatments (amyloid-β protein precursor (APP) regulators, Aβ breakers, active and passive immunotherapy with vaccines and antibodies, β - and γ - secretase inhibitors or modulators), (iii) anti-tau treatments, (iv) pleiotropic products (most of them of natural origin), (v) epigenetic intervention, and (vi) combination therapies. The implementation of pharmacogenomic strategies will contribute to optimize drug development and therapeutics in AD and related disorders

  9. Mining Social Entrepreneurship Strategies Using Topic Modeling

    PubMed Central

    2016-01-01

    Despite the burgeoning research on social entrepreneurship (SE), SE strategies remain poorly understood. Drawing on extant research on the social activism and social change, empowerment and SE models, we explore, classify and validate the strategies used by 2,334 social entrepreneurs affiliated with the world’s largest SE support organization, Ashoka. The results of the topic modeling of the social entrepreneurs’ strategy profiles reveal that they employed a total of 39 change-making strategies that vary across resources (material versus symbolic strategies), specificity (general versus specific strategies), and mode of participation (mass versus elite participation strategies); they also vary across fields of practice and time. Finally, we identify six meta-SE strategies―a reduction from the 39 strategies―and identify four new meta-SE strategies (i.e., system reform, physical capital development, evidence-based practices, and prototyping) that have been overlooked in prior SE research. Our findings extend and deepen the research into SE strategies and offer a comprehensive model of SE strategies that advances theory, practice and policy making. PMID:26998970

  10. Summary: analysis of alternative FBR development strategies

    SciTech Connect

    Burnham, J.B.

    1981-12-01

    This report summarizes the comparative evaluation of alternative strategies for the development of the commercial fast breeder reactor (FBR) in the United States. For planning purposes, a range of possible FBR development paths called strategies were selected for evaluation. These strategies, designed to be technically and economically feasible, were expressed in terms of the timing and nature of facilities/research and development programs required to reach full power operation of the first commercial FBR. Four of the seven strategies resulted in a large (1457 MWe) FBR as an end point, the other three in a 1000-MWe plant. Probability distributions were calculated for total strategy costs and time to completion. For the seven strategies analyzed, the costs (discounted 1980 dollars) ranged from $1.8 billion to $4.9 billion; the completion times ranged from 24 to 55 years.

  11. A competitive strategy for learning a polygon

    SciTech Connect

    Hoffmann, F.; Kriegel, K.; Icking, C.; Klein, R.

    1997-06-01

    We provide a competitive strategy for a mobile robot with vision, that has to explore an unknown simple polygon starting from and returning to a given point on the boundary. Our strategy creates a tour that does not exceed in length 133 times the length of the optimal watchman route. This paper is the first to describe a complete strategy and to give a proof for such a constant competitive factor.

  12. 8 strategies for hospital borrowers in 2011.

    PubMed

    Blake, James W; Jordahl, Eric A; Majka, Andrew J

    2011-04-01

    Given the likelihood that volatility and unexpected events will continue to challenge the capital markets, healthcare borrowers should implement the following strategic responses: Protect the organization's credit rating. Identify and address organizationwide risk. Establish a global capital strategy for the hospital. Diversify debt and investments. Anticipate challenges in the banking market. Anticipate challenges in the municipal bond market. Fully integrate leasing into the organization's capital structure strategy. Ensure the solidity of the organization's financial plan and future strategies. PMID:21548431

  13. A Viking satellite orbit trim strategy

    NASA Technical Reports Server (NTRS)

    Hintz, G. R.

    1971-01-01

    One strategy is submitted for meeting the varied and stringent requirements of the Viking Project on the control of the satellite orbit to obtain reconnaissance and to prepare for lander release. To satisfy these requirements, different orbit trim maneuver strategies were developed for two typical Viking missions. In addition, a summary of recent numerical results is included to show that this strategy satisfies the mission requirements which have been identified.

  14. Communication strategies in cosmetic surgery websites: an application of Taylor's six-segment message strategy wheel.

    PubMed

    Ahn, Ho-Young Anthony; Wu, Lei; Taylor, Ronald E

    2013-01-01

    Using Taylor's six-segment message strategy wheel as a theoretical framework, this study examines the communication approach (transmission or ritual) and message strategy (ego, social, sensory, routine, acute need, or ration) of cosmetic surgery websites. A content analysis revealed a fairly even division between transmission and ritual approaches. Ration strategy was the exclusive strategy in the websites adopting a transmission approach. No routine or acute need strategies were observed. Websites incorporating the ritual approach used ego, social, and sensory strategies. Human female models and natural objects were incorporated to deliver emotional persuasion. Implications for cosmetic surgery web marketers are discussed.

  15. Implementation strategies: recommendations for specifying and reporting.

    PubMed

    Proctor, Enola K; Powell, Byron J; McMillen, J Curtis

    2013-12-01

    Implementation strategies have unparalleled importance in implementation science, as they constitute the 'how to' component of changing healthcare practice. Yet, implementation researchers and other stakeholders are not able to fully utilize the findings of studies focusing on implementation strategies because they are often inconsistently labelled and poorly described, are rarely justified theoretically, lack operational definitions or manuals to guide their use, and are part of 'packaged' approaches whose specific elements are poorly understood. We address the challenges of specifying and reporting implementation strategies encountered by researchers who design, conduct, and report research on implementation strategies. Specifically, we propose guidelines for naming, defining, and operationalizing implementation strategies in terms of seven dimensions: actor, the action, action targets, temporality, dose, implementation outcomes addressed, and theoretical justification. Ultimately, implementation strategies cannot be used in practice or tested in research without a full description of their components and how they should be used. As with all intervention research, their descriptions must be precise enough to enable measurement and 'reproducibility.' We propose these recommendations to improve the reporting of implementation strategies in research studies and to stimulate further identification of elements pertinent to implementation strategies that should be included in reporting guidelines for implementation strategies.

  16. Strategy Guideline: High Performance Residential Lighting

    SciTech Connect

    Holton, J.

    2012-02-01

    The Strategy Guideline: High Performance Residential Lighting has been developed to provide a tool for the understanding and application of high performance lighting in the home. The high performance lighting strategies featured in this guide are drawn from recent advances in commercial lighting for application to typical spaces found in residential buildings. This guide offers strategies to greatly reduce lighting energy use through the application of high quality fluorescent and light emitting diode (LED) technologies. It is important to note that these strategies not only save energy in the home but also serve to satisfy the homeowner's expectations for high quality lighting.

  17. Implementation strategies: recommendations for specifying and reporting

    PubMed Central

    2013-01-01

    Implementation strategies have unparalleled importance in implementation science, as they constitute the ‘how to’ component of changing healthcare practice. Yet, implementation researchers and other stakeholders are not able to fully utilize the findings of studies focusing on implementation strategies because they are often inconsistently labelled and poorly described, are rarely justified theoretically, lack operational definitions or manuals to guide their use, and are part of ‘packaged’ approaches whose specific elements are poorly understood. We address the challenges of specifying and reporting implementation strategies encountered by researchers who design, conduct, and report research on implementation strategies. Specifically, we propose guidelines for naming, defining, and operationalizing implementation strategies in terms of seven dimensions: actor, the action, action targets, temporality, dose, implementation outcomes addressed, and theoretical justification. Ultimately, implementation strategies cannot be used in practice or tested in research without a full description of their components and how they should be used. As with all intervention research, their descriptions must be precise enough to enable measurement and ‘reproducibility.’ We propose these recommendations to improve the reporting of implementation strategies in research studies and to stimulate further identification of elements pertinent to implementation strategies that should be included in reporting guidelines for implementation strategies. PMID:24289295

  18. Sea Turtles and Strategies for Language Skills.

    ERIC Educational Resources Information Center

    Tippins, Deborah; And Others

    1993-01-01

    Describes teaching strategies, including science activities, for challenging students' misconceptions about turtles and helping limited-English-proficiency students enhance their language proficiency. (PR)

  19. Maneuver strategies for multi-planet missions.

    NASA Technical Reports Server (NTRS)

    Dwivedi, N. P.

    1972-01-01

    This paper compares a number of maneuver strategies for five multi-planet missions, including the single planet strategy of nulling the aim-plane and flight-time errors at the immediate target. Significant differences were found among the strategies in the amount of corrective propellant required and the residual miss at each target. In general, nulling or minimization of the residual miss at the next target was found to be superior to that at the immediate target, when error growth is not nulled early. The best strategy corrects aim-plane and flight-time errors at the next target.

  20. Developing a neighborhood primary care strategy.

    PubMed

    Halley, Marc D; Montijo, Sarah D; Gentz, Dale L; Miro, Lauri M

    2015-11-01

    For building and maintaining a primary care workforce to staff an integrated care delivery strategy, considerations include: > Geographic presence > Patient care modeling > Professional staffing. PMID:26685439

  1. Multigrid solution strategies for adaptive meshing problems

    NASA Technical Reports Server (NTRS)

    Mavriplis, Dimitri J.

    1995-01-01

    This paper discusses the issues which arise when combining multigrid strategies with adaptive meshing techniques for solving steady-state problems on unstructured meshes. A basic strategy is described, and demonstrated by solving several inviscid and viscous flow cases. Potential inefficiencies in this basic strategy are exposed, and various alternate approaches are discussed, some of which are demonstrated with an example. Although each particular approach exhibits certain advantages, all methods have particular drawbacks, and the formulation of a completely optimal strategy is considered to be an open problem.

  2. Speed Management Strategies; A Systematic Review

    PubMed Central

    Sadeghi-Bazargani, Homayoun; Saadati, Mohammad

    2016-01-01

    Objective: To systematically identify the various methods of speed management and their effects. Methods: A systematic search was performed in Science Direct, Ovid Medline, Scopus, PubMed and ProQuest databases from April to June 2015. Hand searching and reference of selected articles were used to improve article identification. Articles published after 1990 which had reported on efficacy/effectiveness of speed management strategies were included. Data were extracted using pre-defined extraction table. Results: Of the 803 retrieved articles, 22 articles were included in this review. Most of the included articles (63%) had before-after design and were done in European countries. Speed cameras, engineering schemes, intelligent speed adaption (ISA), speed limits and zones, vehicle activated sign and integrated strategies were the most common strategies reported in the literature. Various strategies had different effects on mean speed of the vehicles ranging from 1.6 to 10 km/h. Moreover, 8-65% and 11-71% reduction was reported in person injured accidents and fatal accidents, respectively as a result of employing various strategies. Conclusion: Literature revealed positive effects of various speed management strategies. Using various strategies was mostly dependent on road characteristics, driver’s attitude about the strategy as well as economic and technological capabilities of the country. Political support is considered as a main determinant in selecting speed management strategies. PMID:27540546

  3. Onychomycosis: Strategies to Minimize Recurrence.

    PubMed

    Gupta, Aditya K; Elewski, Boni E; Rosen, Ted; Caldwell, Bryan; Pariser, David M; Kircik, Leon H; Bhatia, Neal; Tosti, Antonella

    2016-03-01

    Recurrence (relapse or re-infection) in onychomycosis is common, occurring in 10% to 53% of patients. However, data on prevalence is limited as few clinical studies follow patients beyond 12 months. It has been suggested that recurrence after continuous terbinafine treatment may be less common than with intermittent or continuous itraconazole therapy, probably due to the fungicidal activity of terbinafine, although these differences tended not to be significant. Relapse rates also increase with time, peaking at month 36. Although a number of factors have been suggested to play a role in recurrence, only the co-existence of diabetes has been shown to have a significant impact. Data with topical therapy is sparse; a small study showed amorolfine prophylaxis may delay recurrence. High concentrations of efinaconazole have been reported in the nail two weeks' post-treatment suggesting twice monthly prophylaxis with topical treatments may be a realistic option, and may be an important consideration in diabetic patients with onychomycosis. Data suggest that prophylaxis may need to be continued for up to three years for optimal effect. Treating tinea pedis and any immediate family members is also critical. Other preventative strategies include avoiding communal areas where infection can spread (such as swimming pools), and decontaminating footwear. PMID:26954312

  4. CMP-compatible alignment strategy

    NASA Astrophysics Data System (ADS)

    Rouchouze, Eric; Darracq, Jean-Michel; Gemen, Jack

    1997-07-01

    As semiconductor technology continues its way towards smaller geometries, CMP has gained acceptance as the planarization technique for interconnect layers. Its benefits are well known, especially in terms of imaging. However, one of its major drawbacks is to make difficult the alignment of interconnect layers, since a planarized alignment mark is less visible for the stepper's alignment system. Usual workarounds include the clearing of process layers from the alignment mark before exposing the product layer. Although these workarounds provide a temporary solution, they are too costly to be viable in a mass production environment. In this experiment, a non-zero alignment strategy using new mark designs has been tested on the backend layers of a 0.35 micrometers CMOS process. New mark designs have been evaluated, where the space part of the gratings has been filled with 'segments' of various width, the purpose being to minimize the planarization effect of the metallization process. For the selection of the best mark design, several criteria have been taken into account: the stepper's built-in alignment diagnostic software provides information on the quality of the alignment signal. The most important criterion is the product overlay measurement and its repeatability. Marks cross sections using a FIB/SEM tool give indications on the mark profile after metal deposition.

  5. Prevention strategies in prostate cancer.

    PubMed

    Trottier, Greg; Lawrentschuk, N; Fleshner, N E

    2010-09-01

    Prostate cancer (PCa) prevention has been an exciting and controversial topic since the results of the Prostate Cancer Prevention Trial (PCPT) were published. With the recently published results of the reduce (Reduction by Dutasteride of Prostate Cancer Events) trial, interest in this topic is at a peak. Primary pca prevention will be unlikely to affect mortality significantly, but the reduction in overtreatment and the effect on quality of life from the avoidance of a cancer diagnosis are important factors to consider.This review provides a comparative update on the REDUCE and PCPT trials and some clinical recommendations. Other potential primary preventive strategies with statins, selective estrogen response modulators, and nutraceutical compounds-including current evidence for these agents and their roles in clinical practice-are discussed. Many substances that have been examined in the primary prevention of pca and for which clinical data are either negative or particularly weak are not covered.The future of PCa prevention continues to expand, with several ongoing clinical trials and much interest in tertiary prostate cancer prevention. PMID:20882132

  6. Innovative simulation strategies in education.

    PubMed

    Aebersold, Michelle; Tschannen, Dana; Bathish, Melissa

    2012-01-01

    The use of simulation in the undergraduate nursing curriculum is gaining popularity and is becoming a foundation of many nursing programs. The purpose of this paper is to highlight a new simulation teaching strategy, virtual reality (VR) simulation, which capitalizes on the technological skills of the new generation student. This small-scale pilot study focused on improving interpersonal skills in senior level nursing students using VR simulation. In this study, a repeated-measure design was used to evaluate the effectiveness of VR simulation on improving student's performance over a series of two VR scenarios. Using the Emergency Medicine Crisis Resource Management (EMCRM) tool, student performance was evaluated. Overall, the total EMCRM score improved but not significantly. The subscale areas of communication (P = .047, 95% CI: - 1.06, -.007) and professional behavior (P = .003, 95% CI: - 1.12, -.303) did show a significant improvement between the two scenario exposures. Findings from this study show the potential for virtual reality simulations to have an impact on nursing student performance.

  7. Mask strategy at International SEMATECH

    NASA Astrophysics Data System (ADS)

    Kimmel, Kurt R.

    2002-08-01

    International SEMATECH (ISMT) is a consortium consisting of 13 leading semiconductor manufacturers from around the globe. Its objective is to develop the infrastructure necessary for its member companies to realize the International Technology Roadmap for Semiconductors (ITRS) through efficiencies of shared development resources and knowledge. The largest area of effort is lithography, recognized as a crucial enabler for microelectronics technology progress. Within the Lithography Division, most of the efforts center on mask-related issues. The development strategy at International SEMATCH will be presented and the interlock of lithography projects clarified. Because of the limited size of the mask production equipment market, the business case is weak for aggressive investment commensurate with the pace of the International Technology Roadmap for Semiconductors. With masks becoming the overwhelming component of lithography cost, new ways of reducing or eliminating mask costs are being explored. Will mask technology survive without a strong business case? Will the mask industry limit the growth of the semiconductor industry? Are advanced masks worth their escalating cost? An analysis of mask cost from the perspective of mask value imparted to the user is presented with examples and generic formulas for the reader to apply independently. A key part to the success for both International SEMATECH and the industry globally will be partnerships on both the local level between mask-maker and mask-user, and the macro level where global collaborations will be necessary to resolve technology development cost challenges.

  8. Smoking Cessation Strategies in Pregnancy.

    PubMed

    Leung, Lesley W S; Davies, Gregory A

    2015-09-01

    Although pregnancy often motivates women to quit smoking, 20% to 25% will continue to smoke. Smoking is associated with adverse obstetric and neonatal outcomes such as placental abruption, stillbirth, preterm birth and sudden infant death syndrome, and it is therefore important to motivate women to quit during pregnancy. In this review, we explore the efficacy and evidence for safety of strategies for smoking cessation in pregnancy, including behavioural and pharmacologic therapies. The PubMed, Medline, EMBASE, and Cochrane databases (1990 to 2014) were accessed to identify relevant studies, using the search terms "smoking cessation," "pregnancy," "medicine, behavioural," "nicotine replacement products," "bupropion," and "varenicline." Studies were selected based on the levels of evidence presented by the Canadian Task Force on Preventative Health Care. Based on our review of the evidence, incentives combined with behavioural therapy appear to show the greatest promise for abstaining from smoking in the pregnant population. Nicotine replacement therapy administered in the form of gum may be better than using transdermal forms to avoid high levels of nicotine in the fetal circulation. One small trial demonstrated that bupropion is an effective aid for smoking cessation and that it does not appear to be associated with an increased risk of major congenital malformations. The currently available studies of varenicline in pregnancy are insufficient to provide evidence for the safety or efficacy of its use.

  9. Strategies to Increase Physical Activity

    PubMed Central

    Tuso, Phillip

    2015-01-01

    The benefits of physical activity are well known and well publicized. Healthy People 2020 has determined that physical activity is one of their key interventions to improve health in America. Despite wide acceptance that physical activity is a low-cost alternative to disease treatment and prevention, most Americans still do not exercise the recommended minimum of 150 minutes per week. Underpinning such recommendations is the growing concern that unless we change our behavior around active living, health care costs to treat preventable disease will become unsustainable and have a substantial impact on the financial health of the US. For this reason, physicians, health care executives, and community leaders are working together to improve total health for all Americans. One key intervention to prevent preventable diseases and to make health care more affordable is to increase the percentage of Americans who are physically active. No single intervention will increase activity rates, but a group of interventions working together in synergy may be the stimulus needed to get Americans moving. The five strategies discussed in this paper include 1) measure physical activity as a vital sign; 2) encourage patients to be physically active at least 150 minutes per week; 3) create healthy environments by making it easier for patients to be physically active where they live, learn, work, play, and pray; 4) monitor disease incidence of patients who are physically active vs those who are not physically active; and 5) spread best practices. PMID:26517440

  10. Toward a microgravity research strategy

    NASA Technical Reports Server (NTRS)

    1992-01-01

    Recommendations of the Committee on Microgravity Research (CMGR) of the Space Studies Board of the National Research Council are found in the Summary and Recommendations in the front of the report. The CMGR recommends a long-range research strategy. The main rationale for the microgravity research program should be to improve our fundamental scientific and technical knowledge base, particularly in the areas that are likely to lead to improvements in processing and manufacturing on earth. The CMGR recommends research be categorized as Biological science and technology, Combustion, Fluid science, Fundamental phenomena, Materials, and Processing science and technology. The committee also recommends that NASA apply a set of value criteria and measurement indicators to define the research and analysis program more clearly. The CMGR recommends that the funding level for research and analysis in microgravity science be established as a fixed percentage of the total program of NASA's Microgravity Science and Applications Division in order to build a strong scientific base for future experiments. The committee also recommends a cost-effective approach to experiments. Finally the CMGR recommends that a thorough technical review of the centers for commercial development of space be conducted to determine the quality of their activities and to ascertain to what degree their original mission has been accomplished.

  11. Infinite resources: the ultimate strategy

    SciTech Connect

    Goeller, H.E.; Zucker, A.

    1984-02-03

    If the author's projections of world demand for nonrenewable materials prove to be reasonably correct, then it seems highly likely that currently economic resources of many important elements will be in inadequate supply by 2100. At the same time, the prospects appear good that resources of more than 30 elements can be made virtually unlimited if sufficient R and D is invested. Eventually a number of elements will undoubtedly become too scarce and expensive to use except for a few vital purposes. However, there is plenty of time before resources of any limited material become completely economically depleted in which to develop adequate substitutes by using more plentiful materials. The ability to tailor new materials to set specifications is advancing rapidly, and our capabilities in this direction should grow with time if R and D in this area is adequately supported. Although a strategy of infinite resources may be difficult to pursue in the face of global political uncertainties, success would mean that future shortages will be at most only transient events and that a stable population of 8.5 billion people will not be imperiled or impoverished by the lack of materials required for civilized life. 20 references, 3 tables.

  12. Configuration Management Process Assessment Strategy

    NASA Technical Reports Server (NTRS)

    Henry, Thad

    2014-01-01

    Purpose: To propose a strategy for assessing the development and effectiveness of configuration management systems within Programs, Projects, and Design Activities performed by technical organizations and their supporting development contractors. Scope: Various entities CM Systems will be assessed dependent on Project Scope (DDT&E), Support Services and Acquisition Agreements. Approach: Model based structured against assessing organizations CM requirements including best practices maturity criteria. The model is tailored to the entity being assessed dependent on their CM system. The assessment approach provides objective feedback to Engineering and Project Management of the observed CM system maturity state versus the ideal state of the configuration management processes and outcomes(system). center dot Identifies strengths and risks versus audit gotcha's (findings/observations). center dot Used "recursively and iteratively" throughout program lifecycle at select points of need. (Typical assessments timing is Post PDR/Post CDR) center dot Ideal state criteria and maturity targets are reviewed with the assessed entity prior to an assessment (Tailoring) and is dependent on the assessed phase of the CM system. center dot Supports exit success criteria for Preliminary and Critical Design Reviews. center dot Gives a comprehensive CM system assessment which ultimately supports configuration verification activities.*

  13. Strategies of learning from failure.

    PubMed

    Edmondson, Amy C

    2011-04-01

    Many executives believe that all failure is bad (although it usually provides Lessons) and that Learning from it is pretty straightforward. The author, a professor at Harvard Business School, thinks both beliefs are misguided. In organizational life, she says, some failures are inevitable and some are even good. And successful learning from failure is not simple: It requires context-specific strategies. But first leaders must understand how the blame game gets in the way and work to create an organizational culture in which employees feel safe admitting or reporting on failure. Failures fall into three categories: preventable ones in predictable operations, which usually involve deviations from spec; unavoidable ones in complex systems, which may arise from unique combinations of needs, people, and problems; and intelligent ones at the frontier, where "good" failures occur quickly and on a small scale, providing the most valuable information. Strong leadership can build a learning culture-one in which failures large and small are consistently reported and deeply analyzed, and opportunities to experiment are proactively sought. Executives commonly and understandably worry that taking a sympathetic stance toward failure will create an "anything goes" work environment. They should instead recognize that failure is inevitable in today's complex work organizations.

  14. Taiwanese EFL Learners' Perceived Use of Online Reading Strategies

    ERIC Educational Resources Information Center

    Chen, Lisa Wen Chun

    2015-01-01

    Reading strategies are beneficial to learners' reading comprehension. The strategies can be divided into different categories, such as global reading strategies, problem solving strategies and support strategies. Most previous studies investigated the importance of reading strategies in the paper-based reading. However, relatively few studies…

  15. University Context and Strategy Making. ASHE 1988 Annual Meeting Paper.

    ERIC Educational Resources Information Center

    Hardy, Cynthia

    The way in which intraorganizational context can influence strategy making is shown by comparing six Canadian universities formulating retrenchment strategies. "Strategy" involves the components of the strategy, the process by which strategy is made, and the context in which strategy is formed. A variety of university contexts are identified with…

  16. Political strategy, business strategy, and the academic medical center: linking theory and practice.

    PubMed

    Souba, W W; Weitekamp, M R; Mahon, J F

    2001-09-01

    The purpose of this paper is to link external political strategy theory to a specific health care setting-that of the academic medical center (AMC). Political strategy encompasses those activities undertaken by AMCs to acquire, develop, and use power (clout, influence, and credibility) to gain an advantage in situations of conflict. It should be differentiated from internal politics, a topic that will not be dealt with in this review. Political strategy should also be distinguished from but not divorced from competitive strategy. As political and social action can change the competitive landscape and the rules of competition, AMCs must become adept in issues management and stakeholder management. The focus on political strategy is a reflection of the enormous changes in the external environment that have impacted AMCs in recent years. These changes have often emerged out of political and social action and they impact significantly on the organization's more traditional business strategies. We suggest that a tighter alignment between political and business strategies in the future will help ensure organizational survival and success. This article reviews the literature and theory in corporate political strategy and illustrates the application of political strategy with examples of issues and problems faced by AMCs. Models of political strategy are well crafted, and this article concludes with succinct observations on the use of political strategies to enhance the business-based strategies of AMCs. Although the focus is on AMCs, the use of political strategies is applicable to any health care institution.

  17. The Main Idea Strategy: A Strategy to Improve Reading Comprehension through Inferential Thinking

    ERIC Educational Resources Information Center

    Boudah, Daniel J.

    2014-01-01

    This article introduces the Main Idea Strategy, a strategy to improve the performance of students with disabilities and students who perform poorly on reading comprehension tasks. The rationale, research background, and detailed implementation information are presented.

  18. Parallel strategies for SAR processing

    NASA Astrophysics Data System (ADS)

    Segoviano, Jesus A.

    2004-12-01

    This article proposes a series of strategies for improving the computer process of the Synthetic Aperture Radar (SAR) signal treatment, following the three usual lines of action to speed up the execution of any computer program. On the one hand, it is studied the optimization of both, the data structures and the application architecture used on it. On the other hand it is considered a hardware improvement. For the former, they are studied both, the usually employed SAR process data structures, proposing the use of parallel ones and the way the parallelization of the algorithms employed on the process is implemented. Besides, the parallel application architecture classifies processes between fine/coarse grain. These are assigned to individual processors or separated in a division among processors, all of them in their corresponding architectures. For the latter, it is studied the hardware employed on the computer parallel process used in the SAR handling. The improvement here refers to several kinds of platforms in which the SAR process is implemented, shared memory multicomputers, and distributed memory multiprocessors. A comparison between them gives us some guidelines to follow in order to get a maximum throughput with a minimum latency and a maximum effectiveness with a minimum cost, all together with a limited complexness. It is concluded and described, that the approach consisting of the processing of the algorithms in a GNU/Linux environment, together with a Beowulf cluster platform offers, under certain conditions, the best compromise between performance and cost, and promises the major development in the future for the Synthetic Aperture Radar computer power thirsty applications in the next years.

  19. A Strategy for Mars Exopaleontology

    NASA Technical Reports Server (NTRS)

    Farmer, Jack D.; DesMarais, David J.; Chang, Sherwood (Technical Monitor)

    1995-01-01

    There is compelling geological evidence that the climate of early Mars was much more Earth-like, with a denser atmosphere and abundant surface water. Given that life developed on the Earth very quickly (between 4.2 and 3.5 Ga), it is quite plausible that life may have also developed on Mars during this early clement period. If Martian life developed, it is likely to have left behind a fossil record. Thus, an important focus for upcoming Mars missions is to explore for an ancient biosphere. This presents a set of goals and problems that are quite distinct from Exobiology. I call this new activity "Exopaleontology", whose core principles derive from studies of the Precambrian fossil record on Earth, biosedimentology and microbial fossilization. Such studies reveal that the most important factor favoring the long-term preservation of microbial fossils is rapid entombment of microorganisms by fine-grained, stable mineral phases such as silica, phosphate, carbonate and metal sulfides. Terrestrial environments where such aqueous mineral phases frequently entomb and preserve microorganisms include subaerial and subaqueous springs and shallow hydrothermal systems, evaporitic alkaline lakes, "hardpan" soils (e.g. calcretes, silcretes, ferracretes), and frozen soils or ground ice. With the exception of ice, which has a short crustal residence time, such deposits am known to retain a record of terrestrial life for billions of years. Current activities seek to refine and apply this strategy to the Mars Global Surveyor missions and beyond. Ongoing studies of microbial fossilization in each of the target environments identified above are aimed at improving our understanding of how biological information is incorporated into aqueous mineral deposits and preserved. Viking data is being used to target sites for high resolution orbital imaging and spectroscopy during upcoming Mars missions. Such data will provide a basis for selecting sites for future landed missions and eventually

  20. Energy strategy: Roadmap to consensus

    SciTech Connect

    Not Available

    1990-11-01

    The United States lacks a comprehensive approach to policy-making in the energy realm. Today, as in the past, individual constituency groups tend to focus on their particular aspect of the energy challenge. Many employ a decide-announce-defend'' approach to policy-making, setting out to secure a unilateral advantage for themselves. By so doing, they inevitably pit interest against interest. The result is a polarization of constituencies, and shortsighted policies designed to address the issue of the moment. The American Energy Assurance Council (AEAC) is a non-profit organization founded in 1987 for the sole purpose of facilitating progress toward a fair efficient wise, stable, and consensus-based national energy strategy. AEAC does not have a substantive policy agencies. Rather, we are committed to supporting a process whereby the many stakeholders and policy makers concerned with energy-related issues can come together in productive discourse, thereby overcoming ignorance of each other's positions. The Council seeks to act as a facilitative body, providing a safe'' context for inventive and creative thinking. We attempt to build a store of common knowledge, and to build on that store according to mutually agreed-upon groundrules, and employing sophisticated approaches to facilitation and mediation. This report, the National Energy Consensus Experiment (NECE), was an ambitious experiment in consensus-building. We learned a great deal from it, both in terms of substance and process, and we are convinced that it holds important lessons for others who may seek to build consensus in the public policy realm.

  1. Energy strategy: Roadmap to consensus

    SciTech Connect

    Not Available

    1990-11-01

    The United States lacks a comprehensive approach to policy-making in the energy realm. Today, as in the past, individual constituency groups tend to focus on their particular aspect of the energy challenge. Many employ a ``decide-announce-defend`` approach to policy-making, setting out to secure a unilateral advantage for themselves. By so doing, they inevitably pit interest against interest. The result is a polarization of constituencies, and shortsighted policies designed to address the issue of the moment. The American Energy Assurance Council (AEAC) is a non-profit organization founded in 1987 for the sole purpose of facilitating progress toward a fair efficient wise, stable, and consensus-based national energy strategy. AEAC does not have a substantive policy agencies. Rather, we are committed to supporting a process whereby the many stakeholders and policy makers concerned with energy-related issues can come together in productive discourse, thereby overcoming ignorance of each other`s positions. The Council seeks to act as a facilitative body, providing a ``safe`` context for inventive and creative thinking. We attempt to build a store of common knowledge, and to build on that store according to mutually agreed-upon groundrules, and employing sophisticated approaches to facilitation and mediation. This report, the National Energy Consensus Experiment (NECE), was an ambitious experiment in consensus-building. We learned a great deal from it, both in terms of substance and process, and we are convinced that it holds important lessons for others who may seek to build consensus in the public policy realm.

  2. Immunotherapeutic strategies in autoimmune uveitis

    PubMed Central

    Papotto, Pedro Henrique; Marengo, Eliana Blini; Sardinha, Luiz Roberto; Goldberg, Anna Carla; Rizzo, Luiz Vicente

    2014-01-01

    Autoimmune uveitis is an organ-specific disorder characterized by irreversible lesions to the eye that predominantly affect people in their most productive years and is among the leading causes of visual deficit and blindness. Currently available therapies are effective in the treatment of a wide spectrum of uveitis, but are often associated with severe side effects. Here, we review ongoing research with promising immunomodulatory therapeutic strategies, describing their specific features, interactions and the responses triggered by the targeted immune molecules that aim to minimize clinical complications and the likelihood of disease relapse. We first review the main features of the disease, diagnostic tools, and traditional forms of therapy, as well as the animal models predominantly used to understand the pathogenesis and test the novel intervention approaches aiming to control the acute immune and inflammatory responses and to dampen chronic responses. Both exploratory research and clinical trials have targeted either the blockade of effector pathways or of their companion co-stimulatory molecules. Examples of targets are T cell receptors (CD3), their co-stimulatory receptors (CD28, CTLA-4) and corresponding ligands (B7-1 and B7-2, also known as CD80 and CD86), and cytokines like IL-2 and their receptors. Here, we summarize the available evidence on effectiveness of these treatments in human and experimental uveitis and highlight a novel CD28 antagonist monovalent Fab′ antibody, FR104, which has shown preclinical efficacy suppressing effector T cells while enhancing regulatory T cell function and immune tolerance in a humanized graft-versus-host disease (GVHD) mice model and is currently being tested in a mouse autoimmune uveitis model with encouraging results. PMID:24833504

  3. Are your physician-integration strategies sustainable?

    PubMed

    Pizzo, James J; Fitz, Todd

    2012-11-01

    Before embarking on a physician-integration strategy, hospitals and health systems should perform a detailed analysis of the following four critical areas to ensure that the strategy is competitive and sustainable: Strategic objectives; Financial resources; Requisite experience and functional capabilities; Organizational structure, culture, and commitment. PMID:23173364

  4. Children's Learning Strategies in Language Immersion Classrooms.

    ERIC Educational Resources Information Center

    Chamot, Anna Uhl; El-Dinary, Pamela Beard

    This paper reports on an investigation of learning strategy applications in elementary foreign language immersion classrooms. The focus of the paper is on identifying strategies more and less effective learners use for classroom reading and writing tasks in the target language. Think-aloud data from third grade and fourth grade students were…

  5. Computer Acquisition: The Carnegie-Mellon Strategy.

    ERIC Educational Resources Information Center

    McCredie, John W.

    1979-01-01

    Describes the strategy used at Carnegie-Mellon University for providing adequate services for the increasing demands of campus computing. This strategy combines the flexibility of leasing with the economy of outright purchase by acquiring smaller systems at frequent intervals and distributing processing. (CMV)

  6. Knowledge Strategies for Enhancing School Learning Capacity

    ERIC Educational Resources Information Center

    Cheng, Eric

    2012-01-01

    Purpose: The purpose of this paper is to identify the knowledge strategies applied in aided secondary schools in Hong Kong and to explore the predictive relationship between knowledge strategies and school learning capacity. Design/methodology/approach: A cross-sectional quantitative survey was designed to collect data from 427 teachers at 15…

  7. Motivational Strategies that Work! Fall 2006

    ERIC Educational Resources Information Center

    Educators' Spotlight Digest, 2006

    2006-01-01

    This column is a collaborative effort by library media specialists and K-16 educators who write about the motivational strategies that have worked for them in teaching IL skills. Motivational strategies include ways to gain and sustain attention, increase relevance for learning information literacy skills, build confidence in students' developing…

  8. Leadership Strategies for Community College Executives.

    ERIC Educational Resources Information Center

    Myran, Gunder; Baker, George A., III; Simone, Beverly; Zeiss, Tony

    This book on community college executive leadership strategies includes the following chapters: (1) "Leadership Strategies: An Overview" by Gunder Myran; (2) "Achieving Transformational Change" by George A. Baker, III; (3) "Strategic Elements of Organizational Design" by Gunder Myran; (4) "Strategic Dimensions of Policy Development" by Gunder…

  9. Pain Coping Strategies in Osteoarthritis Patients.

    ERIC Educational Resources Information Center

    Keefe, Francis J.; And Others

    1987-01-01

    Investigated the relation of pain coping strategies to pain, health status, and psychological distress in a group of osteoarthritis patients with chronic pain. Patients completed various questionnaires. Medical status variables were also used. The Pain Control and Rational Thinking factor derived from the Coping Strategies Questionnaire proved to…

  10. Teachers' Orientations towards Selecting Assessment Strategies

    ERIC Educational Resources Information Center

    Berry, Rita

    2010-01-01

    Background: The literature suggests two main types of orientations influencing teachers' choice of assessment strategies--"Knowledge acquisition and retention (K orientation)" and "Understanding and Conceptual change (U orientation)" with the former more directly related to surface learning types of assessment strategies and the latter more to do…

  11. Strategy: The logic of war and peace

    SciTech Connect

    Luttwak, E.N.

    1987-01-01

    This book expounds a new way of thinking about the conduct of war and the diplomacy of peace, a theory Luttwak calls ''paradoxical logic,'' and illustrates, through abundant historical examples, the failure of commonsense logic in matters of military strategy and international politics. Topics considered include nuclear weapons, military strategy, decision making, historical aspects, political aspects, global aspects, and warfare.

  12. Student Language Learning Strategies across Eight Disciplines.

    ERIC Educational Resources Information Center

    Peacock, Matthew; Ho, Belinda

    2003-01-01

    Investigated the use of 50 common second language learning strategies by English for academic purposes students across eight disciplines--building, business, computing, engineering, English, mathematics, primary education, and science--in a university in Hong Kong. Compared and contrasted strategy use across disciplines and examined relationships…

  13. A Marketing Strategy for Spanish for Business.

    ERIC Educational Resources Information Center

    Grosse, Christine Uber

    The development of a marketing strategy for business Spanish courses by means of situational analysis is described. The planner of marketing strategy must consider demand for a course, institutional acceptance, and financial support. A survey of 508 universities revealed a low level of demand for business Spanish which could potentially be…

  14. Implementation Strategies for Educational Intranet Resources.

    ERIC Educational Resources Information Center

    Herson, Katie; Sosabowski, Michael; Lloyd, Andrew; Flowers, Stephen; Paine, Cameron; Newton, Becci

    2000-01-01

    Describes two alternative strategies for intranet implementation based on experiences at the University of Brighton (United Kingdom). Highlights include differing degrees of staff and student utilization; barriers to success; a unified strategy for effective intranet implementation; and how to manage organizational resistance to change.…

  15. Teaching Strategies for K-4 General Music.

    ERIC Educational Resources Information Center

    Teaching Music, 1999

    1999-01-01

    Provides a strategy, from the book entitled "Strategies for Teaching K-4 General Music," that addresses Standard 6A of the National Standards for Music Education. Explains that students will identify characteristics that enables them to make decisions about the form of the composition in listening examples longer than classroom songs. (CMK)

  16. Reading Abilities and Strategies: A Short Introduction

    ERIC Educational Resources Information Center

    Liu, Feng

    2010-01-01

    This paper gives a short analysis of reading abilities and reading strategies. Much research has been done to investigate the nature of reading, though it's had to exactly define reading abilities and strategies. Different kinds of readings are discussed in this paper and distinctions are made between first language reading and second or foreign…

  17. A Case Study about Communication Strategies

    ERIC Educational Resources Information Center

    Lin, Grace Hui Chin

    2011-01-01

    The primary purpose of this case study was to identify what were Taiwanese University English as a Foreign Language (EFL) learners' perceptions about learning communication strategies. This study collected qualitative data about students' beliefs and attitudes as they learned communication strategies. The research question guiding the study was:…

  18. Quantum roulette: an extended quantum strategy

    NASA Astrophysics Data System (ADS)

    Wang, Xiang-Bin; Kwek, L. C.; Oh, C. H.

    2000-12-01

    In a recent paper, Meyer demonstrated that with a quantum computer, an analogous zero-sum classically strategic game played with quantum strategy essentially become a bias game under a mixture of quantum and classical strategy. To illustrate his point, Meyer used a quantum coin tossing event. In this Letter, we generalize Meyer's argument to an N-state game.

  19. Robust Derivation of Risk Reduction Strategies

    NASA Technical Reports Server (NTRS)

    Richardson, Julian; Port, Daniel; Feather, Martin

    2007-01-01

    Effective risk reduction strategies can be derived mechanically given sufficient characterization of the risks present in the system and the effectiveness of available risk reduction techniques. In this paper, we address an important question: can we reliably expect mechanically derived risk reduction strategies to be better than fixed or hand-selected risk reduction strategies, given that the quantitative assessment of risks and risk reduction techniques upon which mechanical derivation is based is difficult and likely to be inaccurate? We consider this question relative to two methods for deriving effective risk reduction strategies: the strategic method defined by Kazman, Port et al [Port et al, 2005], and the Defect Detection and Prevention (DDP) tool [Feather & Cornford, 2003]. We performed a number of sensitivity experiments to evaluate how inaccurate knowledge of risk and risk reduction techniques affect the performance of the strategies computed by the Strategic Method compared to a variety of alternative strategies. The experimental results indicate that strategies computed by the Strategic Method were significantly more effective than the alternative risk reduction strategies, even when knowledge of risk and risk reduction techniques was very inaccurate. The robustness of the Strategic Method suggests that its use should be considered in a wide range of projects.

  20. Assessment of two BWR accident management strategies

    SciTech Connect

    Hodge, S.A.; Petek, M.

    1991-01-01

    Candidate mitigative strategies for management of in-vessel events during the late phase (after core degradation has occurred) of postulated BWR severe accidents were considered at Oak Ridge National Laboratory (ORNL) during 1990. The identification of new strategies was subject to the constraint that they should, to the maximum extent possible, make use of the existing equipment and water resources of the BWR facilities and not require major equipment modifications or additions. As a result of this effort, two of these candidate strategies were recommended for additional assessment. The first is a strategy for containment flooding to maintain the core and structural debris within the reactor vessel in the event that vessel injection cannot be restored to terminate a severe accident sequence. The second strategy pertains to the opposite case, for which vessel injection would be restored after control blade melting had begun; its purpose is to provide an injection source of borated water at the concentration necessary to preclude criticality upon recovering a damaged BWR core. Assessments of these two strategies have been performed during 1991 under the auspices of the Detailed Assessment of BWR In-Vessel Strategies Program. This paper provides a discussion of the motivation for and purpose of these strategies and the potential for their success. 33 refs., 9 figs.

  1. Apology Strategies of Iranian Undergraduate Students

    ERIC Educational Resources Information Center

    Tehrani, Mohammad Dadkhah; Rezaei, Omid; Dezhara, Salman; Kafrani, Reza Soltani

    2012-01-01

    This study investigated the different primary and secondary strategies the Iranian EFL students use in different situations and the effect of gender on this. A questionnaire was developed based on Sugimoto's (1995) to compare the apology strategies used by male and female students, only gender was examined as a variable. The results showed that…

  2. Developing IEC Strategies for Population Programmes.

    ERIC Educational Resources Information Center

    Cohen, Sylvie I.

    1993-01-01

    Proposes a systematic and stepwise approach to the design of population information, education, and communication (IEC) strategies. Clarifies the role of IEC in population programs, details methodological steps to follow in IEC strategy development, and identifies types of research and sources of data needed. (MDH)

  3. Strategies of Administrative Control and Organizational Effectiveness

    ERIC Educational Resources Information Center

    Reimann, Bernard C.; Negandhi, Anant R.

    1975-01-01

    The results of a comparative study of 30 manufacturing firms in India indicated that the most effective organizations tended to choose a unidimensional strategy of administrative control. This strategy consisted of the use of formalized procedures to control decentralized decision-making with respect to both human and material resources. (Author)

  4. Scribing: A Technology-Based Instructional Strategy

    ERIC Educational Resources Information Center

    Harless, Patrick

    2011-01-01

    In this article, the author presents one instructional strategy--scribing--tailored to the Tablet PC. He illustrates the role of the scribe during discussion through two classroom examples: (1) generalizing the polygon sum theorem; and (2) proving the third angle theorem. Then he analyzes scribing as an instructional strategy as well as students'…

  5. Childlessness: Strategies for Coping with Infertility.

    ERIC Educational Resources Information Center

    Woollett, Anne

    1985-01-01

    Examines the coping strategies adopted by 50 infertile men and women. All interviewed had sought medical help, and many became knowledgeable about reproduction and infertility. Redefining the problem and managing negative concepts about infertility were other coping strategies. Seeking social support, positive identities, and other ways of meeting…

  6. Five Strategies for Questioning with Intention

    ERIC Educational Resources Information Center

    Costa, Arthur L.; Kallick, Bena

    2015-01-01

    Masterful teachers don't just ask a lot of questions; they ask questions in a purposeful way. In this article, Costa and Kallick describe five strategies that can help teachers become more purposeful in designing and posing questions. One strategy is to plan questions that elicit student thinking at various cognitive levels, from simple recall of…

  7. A Role Change Strategy: Decentralized Counseling.

    ERIC Educational Resources Information Center

    Sweet, Gilbert A.

    The debate over new counseling roles rages as some counselors are already adopting them. This paper describes alternative counseling-consulting interventions possible with teachers. It suggests a strategy for speeding the process of role change and encouraging counselor-teacher interaction. The strategy is that of decentralizing counseling offices…

  8. Thinking Broadly: Financing Strategies for Youth Programs

    ERIC Educational Resources Information Center

    Deich, Sharon G.; Hayes, Cheryl D.

    2007-01-01

    This publication is part of a series of tools and resources on financing and sustaining youth programming. These tools and resources are intended to help policymakers, program developers, and community leaders develop innovative strategies for implementing, financing, and sustaining effective programs and policies. This strategy brief presents a…

  9. Learning Visualization Strategies: A Qualitative Investigation

    ERIC Educational Resources Information Center

    Halpern, Daniel; Oh, Kyong Eun; Tremaine, Marilyn; Chiang, James; Bemis, Karen; Silver, Deborah

    2015-01-01

    The following study investigates the range of strategies individuals develop to infer and interpret cross-sections of three-dimensional objects. We focus on the identification of mental representations and problem-solving processes made by 11 individuals with the goal of building training applications that integrate the strategies developed by the…

  10. Language Learning Strategy Use and Reading Achievement

    ERIC Educational Resources Information Center

    Ghafournia, Narjes

    2014-01-01

    The current study investigated the differences across the varying levels of EFL learners in the frequency and choice of learning strategies. Using a reading test, questionnaire, and parametric statistical analysis, the findings yielded up discrepancies among the participants in the implementation of language-learning strategies concerning their…

  11. Language Learning Strategy Use across Proficiency Levels

    ERIC Educational Resources Information Center

    Zarei, Abbas, Ali; Baharestani, Nooshin

    2014-01-01

    To investigate the use of language learning strategies (LLS) by Iranian EFL learners across proficiency levels, a total of 180 Iranian adult female EFL learners were selected and divided into three different proficiency level groups. To collect data, Oxford's (1990) Strategy Inventory for Language Learning (SILL) was used. One-way ANOVA procedures…

  12. 78 FR 21275 - Station Blackout Mitigation Strategies

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-10

    ...; ] NUCLEAR REGULATORY COMMISSION 10 CFR Parts 50 and 52 RIN 3150-AJ08 Station Blackout Mitigation Strategies... plant licensees' station blackout mitigation strategies. Appendix A of the draft regulatory basis... document is one of the actions stemming from the NRC's lessons-learned efforts associated with the...

  13. Institutionalising Internationalisation Strategies in Engineering Education

    ERIC Educational Resources Information Center

    Tossavainen, Paivi J.

    2009-01-01

    Internationalising strategies in engineering education have been widely discussed. Globally, at European level, and in Finland, the strategies are formulated to internationalise higher education. Further, in Finland, the discussion of internationality in higher education is lively. Higher education internationalisation is defined through three…

  14. Strategies for Hard Times in Higher Education.

    ERIC Educational Resources Information Center

    Desfosses, Louis R.

    1996-01-01

    Planning and management strategies used in the private sector have practical applications for higher education in a period of systemic and organizational stress. Promising strategies include organizational delayering; employee empowerment; boundless thinking, problem-solving teams; accelerated processes; quality management and improvement; and…

  15. Implementing Low-Cost School Improvement Strategies.

    ERIC Educational Resources Information Center

    McDonnell, Lorraine M.

    1985-01-01

    Explores the link between the management of fiscal retrenchment and the need for more effective schools. Describes school improvement strategies based on the school effectiveness research and on past experience with educational change programs. A final section discusses the potential role of these strategies in the larger context of educational…

  16. Vocabulary Strategies for a Fourth Grade Classroom

    ERIC Educational Resources Information Center

    Howell, Gina

    2012-01-01

    For this project I worked with twelve of my fourth grade students from a local school in the southwestern part of Stokes County, North Carolina on increasing their vocabulary skills through the development and implementation of seven vocabulary strategies. During the Literature Review I came across the following seven strategies: Prediction;…

  17. Innovative Data Collection Strategies in Qualitative Research

    ERIC Educational Resources Information Center

    Onwuegbuzie, Anthony J.; Leech, Nancy L.; Collins, Kathleen M. T.

    2010-01-01

    This article provides an innovative meta-framework comprising strategies designed to guide qualitative data collection in the 21st century. We present a meta-framework comprising strategies for collecting data from interviews, focus groups, observations, and documents/material culture. We present a template for collecting nonverbal data during…

  18. Effective Online Instructional and Assessment Strategies

    ERIC Educational Resources Information Center

    Gaytan, Jorge; McEwen, Beryl C.

    2007-01-01

    The purpose of this study was to better understand the instructional and assessment strategies that are most effective in the online learning environment. Faculty and students identified several strategies for maintaining instructional quality in the online environment, including the importance of using a variety of instructional methods to appeal…

  19. Strategies for Creating New Venture Legitimacy

    ERIC Educational Resources Information Center

    Karlsson, Tomas; Middleton, Karen Williams

    2015-01-01

    New ventures, being heavily subjected to liabilities of newness, are seen to engage in legitimacy strategies to overcome these liabilities. Building on an adapted theoretical framework of organizational legitimacy, self-reported weekly diaries of twelve entrepreneurs were analysed to identify strategies used by new ventures to create legitimacy.…

  20. Out-of-the-Box Marketing Strategies.

    ERIC Educational Resources Information Center

    Smith, Joanna Warren

    1997-01-01

    The new definition of camp includes year-round camp programs for a variety of populations at multiple sites. Developing a marketing strategy involves creating a mission statement that is unique, publishing a year-round marketing strategy, delivering a consistent quality product, and getting people to talk about camp. Sidebar lists elements of how…

  1. National Drug Control Strategy. 2008 Annual Report

    ERIC Educational Resources Information Center

    Office of National Drug Control Policy, 2008

    2008-01-01

    This report presents the 2008 National Drug Control Strategy of the White House Office of National Drug Control Policy. The overarching goal of the President's Strategy is to reduce drug use in America through a balanced approach that focuses on stopping use before it starts, healing America's drug users, and disrupting the market for illegal…

  2. A strategy planner for NASA robotics applications

    NASA Technical Reports Server (NTRS)

    Brodd, S. S.

    1985-01-01

    Automatic strategy or task planning is an important element of robotics systems. A strategy planner under development at Goddard Space Flight Center automatically produces robot plans for assembly, disassembly, or repair of NASA spacecraft from computer aided design descriptions of the individual parts of the spacecraft.

  3. Teaching Effective Problem Solving Strategies for Interns

    ERIC Educational Resources Information Center

    Warren, Louis L.

    2005-01-01

    This qualitative study investigates what problem solving strategies interns learn from their clinical teachers during their internships. Twenty-four interns who completed their internship in the elementary grades shared what problem solving strategies had the greatest impact upon them in learning how to deal with problems during their internship.…

  4. 48 CFR 434.004 - Acquisition strategy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 48 Federal Acquisition Regulations System 4 2010-10-01 2010-10-01 false Acquisition strategy. 434.004 Section 434.004 Federal Acquisition Regulations System DEPARTMENT OF AGRICULTURE SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION General 434.004 Acquisition strategy. (a) The...

  5. Integrating Computer-Mediated Communication Strategy Instruction

    ERIC Educational Resources Information Center

    McNeil, Levi

    2016-01-01

    Communication strategies (CSs) play important roles in resolving problematic second language interaction and facilitating language learning. While studies in face-to-face contexts demonstrate the benefits of communication strategy instruction (CSI), there have been few attempts to integrate computer-mediated communication and CSI. The study…

  6. Two Strategies for Teaching Black Psychology.

    ERIC Educational Resources Information Center

    Fairchild, Halford H.

    This paper examines two strategies for the teaching of Black Psychology. The first strategy is designed for use in undergraduate and graduate seminars. It relies on a course structure that requires each student to complete a weekly reading assignment, to give an oral abstract to the rest of the seminar, and to write a weekly thought paper on a…

  7. College Enhancement Strategies and Socioeconomic Inequality

    ERIC Educational Resources Information Center

    Wolniak, Gregory C.; Wells, Ryan S.; Engberg, Mark E.; Manly, Catherine A.

    2016-01-01

    The study provides new information on the relationships between students' socioeconomic backgrounds, utilization of college enhancement strategies, and subsequent 4-year college enrollment. Enhancement strategies represent student behaviors used to bolster the competitiveness of a college application, such as Advanced Placement exams and a variety…

  8. The Spelling Strategies of Francophone Dyslexic Students

    ERIC Educational Resources Information Center

    Ruberto, Noémia; Daigle, Daniel; Ammar, Ahlem

    2016-01-01

    The development of spelling skill is a very difficult task for students with dyslexia. Spelling in French involves the consideration of various types of knowledge, procedures and strategies. This study aims to describe the spelling strategies of 32 dyslexic students (DYS) aged from 8 to 12 years and to establish links between spelling strategies…

  9. Improving Undergraduate Computer Instruction: Experiments and Strategies

    ERIC Educational Resources Information Center

    Kalman, Howard K.; Ellis, Maureen L.

    2007-01-01

    Today, undergraduate students enter college with increasingly more sophisticated computer skills compared to their counterparts of 20 years ago. However, many instructors are still using traditional instructional strategies to teach this new generation. This research study discusses a number of strategies that were employed to teach a…

  10. Improving Computer Instruction: Experiments and Strategies

    ERIC Educational Resources Information Center

    Kalman, Howard K.; Ellis, Maureen L.

    2004-01-01

    Today, undergraduate students enter college with increasingly more sophisticated computer skills compared to their counterparts of 20 years ago. However, instructors are still using traditional instructional strategies to teach this new generation. This research study examines strategies that instructors employ to teach introductory computer…

  11. 29 CFR 42.6 - Enforcement strategy.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 1 2014-07-01 2013-07-01 true Enforcement strategy. 42.6 Section 42.6 Labor Office of the Secretary of Labor COORDINATED ENFORCEMENT § 42.6 Enforcement strategy. (a) Each Regional Farm Labor Coordinated Enforcement Committee shall annually prepare, on a regional basis, a migrant farm...

  12. Key Actor Perceptions of Athletics Strategy

    ERIC Educational Resources Information Center

    Collins, William Thomas

    2012-01-01

    Athletics strategy refers to specific initiatives within the intercollegiate athletics program that are designed to meet the broader strategic goals of a post-secondary institution. This case focused on athletics strategy decisions that were enacted within the context of organizational change as Cartwright College, a pseudonym, transitioned from a…

  13. Students' Strategies Can Take Us off Guard

    ERIC Educational Resources Information Center

    Keiser, Jane M.

    2012-01-01

    An interesting change has been occurring in the author's middle school mathematics classes. Some students have become creative, free-thinking inventors. If they have had little experience with an operation, they invent strategies of their own. Sometimes these strategies have been well informed and supported by strong mental math skills and a good…

  14. Intrapreneurship: growing a successful hospital diversification strategy.

    PubMed

    Hannon, F

    1987-10-01

    The recent upheaval in the health care industry has left administrators scrambling after strategies that will ensure their organizations' survival. The author discusses Affiliated Healthcare Systems' successful use of a diversification strategy. Special attention is given to explaining how other organizations might use this system's experience to reduce the risks and increase the rewards inherent in this strategic alternative.

  15. Learning Reading Strategies with Online Discussion

    ERIC Educational Resources Information Center

    Liu, I-Fang; Ko, Hwa-Wei; Wu, Sheng-Yi

    2014-01-01

    Teachers experience difficulty demonstrating prediction strategies and leading discussions in traditional classrooms. It is also unclear whether online discussion can contribute to reading comprehension. The purpose of this study is to create an online reading system to investigate whether learners can acquire reading strategies and enhance their…

  16. Communication Strategies in the Foreign Language Classroom

    ERIC Educational Resources Information Center

    Houston, Tony

    2006-01-01

    The focus of the present study is to examine the communication strategies used by learners and teachers in the foreign language classroom. The data is from introductory Spanish classrooms at the university level. The author analyzed the data for instances of communications strategies according to taxonomy developed for ESL studies. Important…

  17. Self-Regulation and Learning Strategies

    ERIC Educational Resources Information Center

    Weinstein, Claire Ellen; Acee, Taylor W.; Jung, JaeHak

    2011-01-01

    Learning strategies are a bit difficult to define since the nomenclatures used in cognitive educational psychology as well as in strategic and self-regulated learning have not yet been standardized across and within these fields of study. The self-regulated use of learning strategies helps enable students to take more responsibility for their own…

  18. A National Strategy for Lifelong Learning.

    ERIC Educational Resources Information Center

    Coffield, Frank, Ed.

    The first paper of this set of 12 conference papers, "Nine Learning Fallacies and Their Replacement by a National Strategy for Lifelong Learning," by Frank Coffield, synthesizes the opinions of other participants, and goes beyond them to set forth an outline of a strategy for lifelong learning in the United Kingdom. Following this introductory…

  19. Teaching Strategies to Improve Algebra Learning

    ERIC Educational Resources Information Center

    Zbiek, Rose Mary; Larson, Matthew R.

    2015-01-01

    Improving student learning is the primary goal of every teacher of algebra. Teachers seek strategies to help all students learn important algebra content and develop mathematical practices. The new Institute of Education Sciences[IES] practice guide, "Teaching Strategies for Improving Algebra Knowledge in Middle and High School Students"…

  20. Hospital survival strategies for the 1980s.

    PubMed

    Bonney, R S

    1983-09-01

    Survival strategies for hospitals and hospital pharmacy departments are presented, and one hospital's development into a health-services system is described. Financial and competitive pressures are forcing institutions to develop new strategies for survival. The primary institutional strategy is diversification--both horizontal and vertical. Diversification can assist in the hospital's growth, increase its asset and revenue bases, and lead to the development of a health-care delivery system. Marketing to physicians and developing information systems are also critical strategies under a prospective payment system. Institutions will need to know the cost of providing care for specific diagnosis-related groups. Strategies must be employed to develop incentives to reduce inpatient acute-care services and to increase productivity. Physicians should be involved in all of the institutional strategies. Strategies for the pharmacy department are basically the same. Pharmacy departments should develop programs to reduce drug use (especially antibiotic use) and information systems that show the actual cost of providing services by diagnosis. The major corporate restructuring and diversification efforts of one hospital are described. The future of hospitals and pharmacy departments will depend on the successful application of the strategies discussed.

  1. Strategies in Urban Community Mental Health.

    ERIC Educational Resources Information Center

    Kellman, Sheppard G.; And Others

    The paper presents an outline for the development of a community mental health program based on assessment of a first grade population in an urban Negro neighborhood and involving a strategy that places primary emphasis on establishing ongoing community sanction and participation in policy-making. The strategy included the development of a…

  2. Evidence-Based Classroom Behaviour Management Strategies

    ERIC Educational Resources Information Center

    Parsonson, Barry S.

    2012-01-01

    This paper reviews a range of evidence-based strategies for application by teachers to reduce disruptive and challenging behaviours in their classrooms. These include a number of antecedent strategies intended to help minimise the emergence of problematic behaviours and a range of those which provide positive consequences for appropriate student…

  3. Motivational Strategies That Work! Winter 2007

    ERIC Educational Resources Information Center

    Educators' Spotlight Digest, 2007

    2007-01-01

    This column is a collaborative effort by library media specialists and K-16 educators who write about the motivational strategies that have worked for them in teaching information literacy (IL) skills. Motivational strategies include ways to gain and sustain attention, increase relevance for learning IL skills, build confidence in students'…

  4. Research of information classification and strategy intelligence extract algorithm based on military strategy hall

    NASA Astrophysics Data System (ADS)

    Chen, Lei; Li, Dehua; Yang, Jie

    2007-12-01

    Constructing virtual international strategy environment needs many kinds of information, such as economy, politic, military, diploma, culture, science, etc. So it is very important to build an information auto-extract, classification, recombination and analysis management system with high efficiency as the foundation and component of military strategy hall. This paper firstly use improved Boost algorithm to classify obtained initial information, then use a strategy intelligence extract algorithm to extract strategy intelligence from initial information to help strategist to analysis information.

  5. The specialized proresolving mediator 17-HDHA enhances the antibody-mediated immune response against influenza virus: Anew class of adjuvant?a

    PubMed Central

    Ramon, Sesquile; Baker, Steven F.; Sahler, Julie M.; Kim, Nina; Feldsott, Eric A.; Serhan, Charles N.; Martínez-Sobrido, Luis; Topham, David J.; Phipps, Richard P.

    2014-01-01

    Influenza viruses remain a critical global health concern. More efficacious vaccines are needed to protect against influenza virus, yet few adjuvants are approved for routine use. Specialized proresolving mediators (SPMs) are powerful endogenous bioactive regulators of inflammation, with great clinical translational properties. Here, we investigated the ability of the SPM 17-HDHA to enhance the adaptive immune response using an OVA immunization model and a pre-clinical influenza vaccination mouse model. Our findings revealed that mice immunized with OVA plus 17-HDHA or with H1N1-derived HA protein plus 17-HDHA increased antigen-specific antibody titers. 17-HDHA increased the number of antibody-secreting cells in vitro as well as the number of HA-specific antibody secreting cells present in the bone marrow. Importantly, the 17-HDHA-mediated increased antibody production was more protective against live pH1N1 influenza infection in mice. This is the first report on the biological effects of omega-3-derived SPMs on the humoral immune response. These findings illustrate a previously unknown biological link between proresolution signals and the adaptive immune system. Furthermore, this work has important implications for the understanding of B cell biology, as well as the development of new potential vaccine adjuvants. PMID:25392529

  6. Adaptive strategies for cumulative cultural learning.

    PubMed

    Ehn, Micael; Laland, Kevin

    2012-05-21

    The demographic and ecological success of our species is frequently attributed to our capacity for cumulative culture. However, it is not yet known how humans combine social and asocial learning to generate effective strategies for learning in a cumulative cultural context. Here we explore how cumulative culture influences the relative merits of various pure and conditional learning strategies, including pure asocial and social learning, critical social learning, conditional social learning and individual refiner strategies. We replicate the Rogers' paradox in the cumulative setting. However, our analysis suggests that strategies that resolved Rogers' paradox in a non-cumulative setting may not necessarily evolve in a cumulative setting, thus different strategies will optimize cumulative and non-cumulative cultural learning.

  7. Computational strategies for tire monitoring and analysis

    NASA Technical Reports Server (NTRS)

    Danielson, Kent T.; Noor, Ahmed K.; Green, James S.

    1995-01-01

    Computational strategies are presented for the modeling and analysis of tires in contact with pavement. A procedure is introduced for simple and accurate determination of tire cross-sectional geometric characteristics from a digitally scanned image. Three new strategies for reducing the computational effort in the finite element solution of tire-pavement contact are also presented. These strategies take advantage of the observation that footprint loads do not usually stimulate a significant tire response away from the pavement contact region. The finite element strategies differ in their level of approximation and required amount of computer resources. The effectiveness of the strategies is demonstrated by numerical examples of frictionless and frictional contact of the space shuttle Orbiter nose-gear tire. Both an in-house research code and a commercial finite element code are used in the numerical studies.

  8. Learning with repeated-game strategies.

    PubMed

    Ioannou, Christos A; Romero, Julian

    2014-01-01

    We use the self-tuning Experience Weighted Attraction model with repeated-game strategies as a computer testbed to examine the relative frequency, speed of convergence and progression of a set of repeated-game strategies in four symmetric 2 × 2 games: Prisoner's Dilemma, Battle of the Sexes, Stag-Hunt, and Chicken. In the Prisoner's Dilemma game, we find that the strategy with the most occurrences is the "Grim-Trigger." In the Battle of the Sexes game, a cooperative pair that alternates between the two pure-strategy Nash equilibria emerges as the one with the most occurrences. In the Stag-Hunt and Chicken games, the "Win-Stay, Lose-Shift" and "Grim-Trigger" strategies are the ones with the most occurrences. Overall, the pairs that converged quickly ended up at the cooperative outcomes, whereas the ones that were extremely slow to reach convergence ended up at non-cooperative outcomes. PMID:25126053

  9. Mixed-Strategy Chance Constrained Optimal Control

    NASA Technical Reports Server (NTRS)

    Ono, Masahiro; Kuwata, Yoshiaki; Balaram, J.

    2013-01-01

    This paper presents a novel chance constrained optimal control (CCOC) algorithm that chooses a control action probabilistically. A CCOC problem is to find a control input that minimizes the expected cost while guaranteeing that the probability of violating a set of constraints is below a user-specified threshold. We show that a probabilistic control approach, which we refer to as a mixed control strategy, enables us to obtain a cost that is better than what deterministic control strategies can achieve when the CCOC problem is nonconvex. The resulting mixed-strategy CCOC problem turns out to be a convexification of the original nonconvex CCOC problem. Furthermore, we also show that a mixed control strategy only needs to "mix" up to two deterministic control actions in order to achieve optimality. Building upon an iterative dual optimization, the proposed algorithm quickly converges to the optimal mixed control strategy with a user-specified tolerance.

  10. Innovative strategies in critical care education.

    PubMed

    Tainter, Christopher R; Wong, Nelson L; Bittner, Edward A

    2015-06-01

    The cadre of information pertinent to critical care medicine continues to expand at a tremendous pace, and we must adapt our strategies of medical education to keep up with the expansion. Differences in learners' characteristics can contribute to a mismatch with historical teaching strategies. Simulation is increasingly popular, but still far from universal. Emerging technology has the potential to improve our knowledge translation, but there is currently sparse literature describing these resources or their benefits and limitations. Directed strategies of assessment and feedback are often suboptimal. Even strategies of accreditation are evolving. This review attempts to summarize salient concepts, suggest resources, and highlight novel strategies to enhance practice and education in the challenging critical care environment.

  11. Cognitive Strategies in Mathematics, Part I: On Children's Strategies for Solving Simple Addition Problems.

    ERIC Educational Resources Information Center

    Braten, Ivar

    1998-01-01

    Demonstrates the merging of cognitive psychology, psychology of mathematics, and special education. Various models of children's addition strategies are reviewed and critiqued. Addition strategy with poor learners should be comprehensive and include interactions between strategies, knowledge, metacognition, motivation, and social factors. (MAK)

  12. Metacognitive Strategy Teaching in the ESL Oral Classroom: Ripple Effect on Non-Target Strategy Use

    ERIC Educational Resources Information Center

    Lam, Wendy Y. K.

    2010-01-01

    While strategy instruction research generally focuses on the effect of the teaching on learners' use of the strategies targeted for instruction, the present study examines the "wash over" effect on learners' use of pre-existing, non-target strategies. The study involved a treatment class and a comparison class in the ESL oral classroom in Hong…

  13. Population communication management training strategy.

    PubMed

    Bayan Salas, E

    1985-01-01

    The discussion presents some thoughts on a general training strategy in information/education/communication (IEC) management which might meet the needs of 3rd world countries. Management by objectives (MBO) has emerged as the central doctrine in management theory and practice since its initial formulation in 1954. Yet, little evidence exists to date of its successful application in IEC activities. Population IEC activities, being staff activities in a nonprofit, public sector program, are in the "twilight zone" of MBO where hasty efforts to comply with the form if not the substance of this management technique can lead to lower levels of performance and achievement than before the goal setting system was implemented. Yet, clearly, IEC managers need the benefits that management by objectives can bring if done properly. It is essential that IEC managers and workers stop looking at IEC materials as end products in themselves but rather as inputs to be combined with other inputs in realizing the desired output of voluntary behavioral change on a mass level. To overcome tendencies toward provincialism, all IEC managers should initially spend time working in other areas of the population program. The experience of using IEC materials and approaches in face-to-face transactions with potential acceptors is a prerequisite to the successful formulation of such materials and approaches. Training programs for IEC managers and supervisors should emphasize development of consensual decision making skills. The success or failure of the program depends on the ability of its workers to resolve potential conflicts between an individual's priorities and national priorities in a noncoercive manner. The social dynamics approach that seeks a conscious, voluntary, nonmanipulated shift of shared attitudes, opinions, feelings, and actions is the approach underlying the most successful population programs. All IEC managers and supervisors should be systematically trained in norm shifting

  14. Regional strategy tested in Caribbean.

    PubMed

    1984-01-01

    Barbados, St. Vincent, and St. Lucia have joined forces in the world's 1st regional Contraceptive Social Marketing (CSM) effort -- the Caribbean CSM. The Barbados Family Planning Association (BFPS) is overseeing the operation, which begins selling 2 contraceptive pills and a condom in early February. Costs and start-up times were shaved by adopting brand names and advertising materials from Jamaica's highly successful CSM project. Jamaica's popular "Panther" condom and "Perle" oral contraceptive (OC) are being used by the Caribbean CSM project. Perle's 9-year-old package has been redesigned and the Caribbean CSM project also is selling a 2nd, low-dose version called "Perle-LD." The products are manufactured in the US by Syntex as Noriday and Norminest, respectively. But the regional approach's financial gains also had a debit side, most notably a tripling of bureaucratic procedures. Part of project difficulties stem from differences among the 3 Caribbean countries. While sharing a common cultural heritage, St. Lucians speak a patois dialect in addition to the English prevalent on the other islands. The biggest hurdle was overcoming an economic disparity between Barbados and its less affluent neighbors, St. Vincent and St. Lucia. The CSM project decided to try a 2-tier product pricing strategy. In US currency, prices run $1.75 per cycle for both OCs on Barbados, but $1.26 on St. Vincent and St. Lucia. A Panther 3-pack costs 75 cents on Barbados and 42 cents on the othe 2 islands. The project is being promoted with generic family planning media advertisements. The project also has held physician orientation seminars on each island. The pilot program will be accompanied by retailer training seminars. In addition the project may introduce a spermicidal foaming tablet, once the US Food and Drug Administration approvs a new American-made product. The unique Caribbean CSM project may spread an idea as potent as the family planning message. Its success could transmit the

  15. Regional strategy tested in Caribbean.

    PubMed

    1984-01-01

    Barbados, St. Vincent, and St. Lucia have joined forces in the world's 1st regional Contraceptive Social Marketing (CSM) effort -- the Caribbean CSM. The Barbados Family Planning Association (BFPS) is overseeing the operation, which begins selling 2 contraceptive pills and a condom in early February. Costs and start-up times were shaved by adopting brand names and advertising materials from Jamaica's highly successful CSM project. Jamaica's popular "Panther" condom and "Perle" oral contraceptive (OC) are being used by the Caribbean CSM project. Perle's 9-year-old package has been redesigned and the Caribbean CSM project also is selling a 2nd, low-dose version called "Perle-LD." The products are manufactured in the US by Syntex as Noriday and Norminest, respectively. But the regional approach's financial gains also had a debit side, most notably a tripling of bureaucratic procedures. Part of project difficulties stem from differences among the 3 Caribbean countries. While sharing a common cultural heritage, St. Lucians speak a patois dialect in addition to the English prevalent on the other islands. The biggest hurdle was overcoming an economic disparity between Barbados and its less affluent neighbors, St. Vincent and St. Lucia. The CSM project decided to try a 2-tier product pricing strategy. In US currency, prices run $1.75 per cycle for both OCs on Barbados, but $1.26 on St. Vincent and St. Lucia. A Panther 3-pack costs 75 cents on Barbados and 42 cents on the othe 2 islands. The project is being promoted with generic family planning media advertisements. The project also has held physician orientation seminars on each island. The pilot program will be accompanied by retailer training seminars. In addition the project may introduce a spermicidal foaming tablet, once the US Food and Drug Administration approvs a new American-made product. The unique Caribbean CSM project may spread an idea as potent as the family planning message. Its success could transmit the

  16. Comparative Effectiveness of STEMI Regionalization Strategies

    PubMed Central

    Concannon, Thomas W.; Kent, David M.; Normand, Sharon-Lise; Newhouse, Joseph P.; Griffith, John L.; Cohen, Joshua; Beshansky, Joni R.; Wong, John B.; Aversano, Thomas; Selker, Harry P.

    2010-01-01

    BACKGROUND Primary percutaneous coronary intervention (PCI) is more effective on average than fibrinolytic therapy (FT) in the treatment of ST-segment elevation myocardial infarction (STEMI). Yet most U.S. hospitals are not equipped for PCI and FT is still widely used. This study evaluated the comparative effectiveness of STEMI regionalization strategies to increase the use of PCI against standard emergency transport and care. METHODS AND RESULTS We estimated incremental treatment costs and quality-adjusted life expectancies of 2,000 patients with STEMI who received PCI or FT in simulations of emergency care in a regional hospital system. To increase access to PCI across the system, we compared a base case strategy to 12 hospital-based strategies of building new PCI labs or extending the hours of existing labs, and one emergency medical services (EMS)-based strategy of transporting all patients with STEMI to existing PCI-capable hospitals. The base case resulted in 609 (569, 647) patients getting PCI. Hospital-based strategies increased the number of patients receiving PCI, the costs of care, and quality-adjusted life years (QALYs) saved, and were cost effective under a variety of conditions. An EMS-based strategy of transporting every patient to an existing PCI facility was less costly and more effective than all hospital expansion options. CONCLUSION Our results suggest that new construction and staffing of PCI labs may not be warranted if an EMS strategy is both available and feasible. PMID:20664025

  17. Evolutionary stability of mixed strategies on graphs

    NASA Astrophysics Data System (ADS)

    Li, Yan; Liu, Xinsheng; Claussen, Jens Christian

    2016-07-01

    Up to the present time, the study of evolutionary dynamics mostly focused on pure strategy games in finite discrete strategy space, either in well-mixed or structured populations. In this paper, we study mixed strategy games in continuous strategy space on graphs of degree k. Each player is arranged on a vertex of the graph. The edges denote the interaction between two individuals. In the limit of weak selection, we first derive the payoff functions of two mixed strategies under three different updating rules, named birth-death, death-birth and imitation. Then we obtain the conditions for a strategy being a continuously stable strategy (CSS), and we also confirm that the equilibrium distribution corresponding to the CSS is neighborhood attracting and strongly uninvadable. Finally, we apply our theory to the prisoner’s dilemma and the snowdrift game to obtain possible CSS. Simulations are performed for the two special games and the results are well consistent with the conclusions we made.

  18. Evolutionary stability of mixed strategies on graphs

    NASA Astrophysics Data System (ADS)

    Li, Yan; Liu, Xinsheng; Claussen, Jens Christian

    2016-07-01

    Up to the present time, the study of evolutionary dynamics mostly focused on pure strategy games in finite discrete strategy space, either in well-mixed or structured populations. In this paper, we study mixed strategy games in continuous strategy space on graphs of degree k. Each player is arranged on a vertex of the graph. The edges denote the interaction between two individuals. In the limit of weak selection, we first derive the payoff functions of two mixed strategies under three different updating rules, named birth–death, death–birth and imitation. Then we obtain the conditions for a strategy being a continuously stable strategy (CSS), and we also confirm that the equilibrium distribution corresponding to the CSS is neighborhood attracting and strongly uninvadable. Finally, we apply our theory to the prisoner’s dilemma and the snowdrift game to obtain possible CSS. Simulations are performed for the two special games and the results are well consistent with the conclusions we made.

  19. Improving epidemic control strategies by extended detection

    NASA Astrophysics Data System (ADS)

    Karp, Paweł; Dybiec, Bartłomiej; Kleczkowski, Adam

    2014-11-01

    Majority of epidemics eradication programs work in preventive responsive way. The lack of exact information about epidemiological status of individuals makes responsive actions less efficient. Here, we demonstrate that additional tests can significantly increase the efficiency of "blind" treatment (vaccination or culling). Eradication strategy consisting of "blind" treatment in very limited local neighborhood supplemented by extra tests in a little bit larger neighborhood is able to prevent invasion of even highly infectious diseases and to achieve this at a cost lower than for the "blind" strategy. The effectiveness of the extended strategy depends on such parameters as the test efficiency and test cost.

  20. Can rewiring strategy control the epidemic spreading?

    NASA Astrophysics Data System (ADS)

    Dong, Chao; Yin, Qiuju; Liu, Wenyang; Yan, Zhijun; Shi, Tianyu

    2015-11-01

    Relation existed in the social contact network can affect individuals' behaviors greatly. Considering the diversity of relation intimacy among network nodes, an epidemic propagation model is proposed by incorporating the link-breaking threshold, which is normally neglected in the rewiring strategy. The impact of rewiring strategy on the epidemic spreading in the weighted adaptive network is explored. The results show that the rewiring strategy cannot always control the epidemic prevalence, especially when the link-breaking threshold is low. Meanwhile, as well as strong links, weak links also play a significant role on epidemic spreading.